-- dump date 20140620_062918 -- class Genbank::CDS -- table cds_note -- id note YP_001471678.1 PFAM: late control D family protein; KEGG: drm:Dred_1216 phage late control D family protein YP_001471679.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: syc:syc0782_c putative bacteriophage protein YP_001471680.1 KEGG: drm:Dred_1214 hypothetical protein YP_001471681.1 PFAM: major tail tube protein; KEGG: drm:Dred_1213 phage major tail tube protein YP_001471682.1 KEGG: drm:Dred_1212 hypothetical protein YP_001471683.1 KEGG: drm:Dred_1210 hypothetical protein YP_001471684.1 KEGG: dsy:DSY2180 hypothetical protein YP_001471685.1 KEGG: spu:585658 hypothetical LOC585658 YP_001471686.1 PFAM: major capsid protein E; KEGG: drm:Dred_1207 hypothetical protein YP_001471688.1 PFAM: peptidase S14 ClpP; KEGG: bam:Bamb_1874 peptidase S14, ClpP YP_001471689.1 TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: drm:Dred_1204 phage portal protein, lambda family YP_001471690.1 PFAM: terminase GpA; KEGG: drm:Dred_1203 phage terminase GpA YP_001471691.1 KEGG: mgm:Mmc1_2754 hypothetical protein YP_001471692.1 PFAM: ParB domain protein nuclease; KEGG: pde:Pden_2068 ParB domain protein nuclease YP_001471693.1 KEGG: xfa:XF0515 hypothetical protein YP_001471694.1 PFAM: ParB domain protein nuclease YP_001471695.1 PFAM: ParB domain protein nuclease; KEGG: ecv:APECO1_517 putative transcriptional regulator YP_001471696.1 KEGG: ent:Ent638_0796 hypothetical protein YP_001471697.1 KEGG: eci:UTI89_C0932 putative endolysin YP_001471698.1 KEGG: rso:RSc1933 probable phage-related transmembrane protein YP_001471699.1 KEGG: ypi:YpsIP31758_2212 hypothetical protein YP_001471700.1 KEGG: yps:YPTB1765 putative GP46 [bacteriophage N15] pir||T13133 protein GP46-... YP_001471701.1 PFAM: protein of unknown function DUF551 YP_001471702.1 KEGG: ecs:ECs1950 hypothetical protein YP_001471704.1 KEGG: pca:Pcar_0531 hypothetical protein YP_001471705.1 PFAM: HNH endonuclease; KEGG: stm:PSLT094.1N hypothetical protein YP_001471706.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: eci:UTI89_C5088 hypothetical protein YP_001471707.1 KEGG: stt:t1914 putative methyltransferase YP_001471708.1 KEGG: ana:all7370 hypothetical protein YP_001471710.1 KEGG: asa:ASA_P4G021 hypothetical protein YP_001471713.1 PFAM: protein of unknown function DUF1064; KEGG: amt:Amet_2598 protein of unknown function DUF1064 YP_001471715.1 KEGG: ypm:YP_pCRY27 ATPase involved in chromosome partitioning YP_001471716.1 KEGG: ecs:ECs1505 hypothetical protein YP_001471717.1 PFAM: helix-turn-helix domain protein; KEGG: pfl:PFL_5188 helix-turn-helix domain protein, putative YP_001471718.1 KEGG: bbr:BB3160 hypothetical protein YP_001471719.1 KEGG: sec:SC2625 putative bacteriophage protein YP_001471720.1 KEGG: reu:Reut_D6449 hypothetical protein YP_001471721.1 PFAM: replication initiation protein; KEGG: sgl:SGP1_0012 replication associated protein RepA1 YP_001471722.1 PFAM: tail assembly chaperone gp38; KEGG: spt:SPA2605 putative phage gene YP_001471723.1 KEGG: bte:BTH_II1333 phage-related tail fiber protein YP_001471724.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: xft:PD1096 phage-related tail protein YP_001471725.1 PFAM: Baseplate J family protein; KEGG: drm:Dred_1220 baseplate J family protein YP_001471727.1 KEGG: drm:Dred_1218 hypothetical protein YP_001471728.1 TIGRFAM: phage baseplate assembly protein V; KEGG: plu:plu3426 hypothetical protein YP_001476239.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001476240.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001476241.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001476242.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001476243.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001476244.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001476245.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001476246.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001476247.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001476248.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001476249.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001476250.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE4201 putative phosphate-binding periplasmic protein YP_001476251.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001476252.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001476253.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001476254.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001476255.1 PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE4193 putative periplasmic solute-binding protein YP_001476256.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE4191 ABC transporter permease YP_001476257.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE4190 putative amino acid transport system permease YP_001476258.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001476259.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: yps:YPTB3953 xanthine/uracil permease family protein YP_001476260.1 KEGG: pfl:PFL_5500 hypothetical protein YP_001476261.1 PFAM: NADPH-dependent FMN reductase; KEGG: yen:YE4184 putative NAD(P)H-dependent FMN reductase YP_001476262.1 KEGG: eca:ECA4463 hypothetical protein YP_001476263.1 KEGG: sbo:SBO_4340 lysine:N6-hydroxylase YP_001476264.1 PFAM: beta-lactamase domain protein; KEGG: sec:SC2881 putative metal-dependent hydrolase of the beta-lactamase superfamily II YP_001476265.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001476266.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001476267.1 PFAM: protein of unknown function DUF37; KEGG: yps:YPTB3947 hypothetical protein YP_001476268.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001476269.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001476270.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001476271.1 binds the polymerase to DNA and acts as a sliding clamp YP_001476272.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001476273.1 negatively supercoils closed circular double-stranded DNA YP_001476274.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001476275.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: yen:YE4167 pyridoxal-phosphate dependent enzyme YP_001476276.1 PFAM: YheO domain protein; KEGG: bvi:Bcep1808_0785 transcriptional regulator, fis family YP_001476277.1 PFAM: major facilitator superfamily MFS_1; KEGG: bch:Bcen2424_3541 major facilitator superfamily MFS_1 YP_001476278.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pol:Bpro_3531 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001476279.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: eca:ECA4419 galactonate operon transcriptional repressor YP_001476280.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: eca:ECA4418 2-dehydro-3-deoxygalactonokinase YP_001476281.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001476282.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4416 DgoA protein [includes: 2-dehydro-3-deoxyphosphogalactonate aldolase; galactonate dehydratase] YP_001476283.1 TIGRFAM: phosphoglycerate transporter; d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4415 putative D-galactonate transporter YP_001476284.1 KEGG: yen:YE4166 hypothetical protein YP_001476285.1 PFAM: protein of unknown function DUF1375; KEGG: eca:ECA4404 putative lipoprotein YP_001476286.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001476287.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001476288.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ypp:YPDSF_0014 membrane protein YP_001476289.1 PFAM: PilT protein domain protein; KEGG: ret:RHE_PF00555 hypothetical protein YP_001476290.1 KEGG: ecs:ECs4816 hypothetical protein YP_001476291.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001476292.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001476293.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: eca:ECA2757 hypothetical protein YP_001476294.1 PFAM: plasmid stabilization system; KEGG: eca:ECA2758 hypothetical protein YP_001476295.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yen:YE4159 putative D-isomer specific 2-hydroxyacid dehydrogenase YP_001476296.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ent:Ent638_0168 major facilitator superfamily MFS_1 YP_001476297.1 PFAM: PfkB domain protein; KEGG: kpn:KPN_03913 putative kinase YP_001476298.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_03912 putative sugar phosphate isomerase/epimerase YP_001476299.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_03911 putative transcriptional regulator YP_001476300.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: yen:YE4156 putative lipoprotein YP_001476301.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0081 putative GNAT-family acetyltransferase YP_001476302.1 KEGG: yen:YE4152 DNA-3-methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001476303.1 KEGG: spt:SPA2157 outer membrane esterase; TIGRFAM: outer membrane autotransporter barrel domain; PFAM: lipolytic protein G-D-S-L family; Autotransporter beta- domain protein YP_001476304.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: yen:YE1026 LuxR-family transcriptional regulator YP_001476305.1 PFAM: autoinducer synthesis protein; KEGG: eca:ECA0105 N-acylhomoserine lactone synthesis protein YP_001476306.1 PFAM: major facilitator superfamily MFS_1; KEGG: bmb:BruAb1_1939 major facilitator family transporter YP_001476307.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001476308.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001476309.1 KEGG: yen:YE4149 hypothetical protein YP_001476310.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: yen:YE4148 PTS system, mannitol-specific IIABC component YP_001476311.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yen:YE4147 mannitol-1-phosphate 5-dehydrogenase YP_001476312.1 Acts as a repressor of the mtlAD operon YP_001476313.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: yen:YE4145 putative inner membrane protein YP_001476314.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE4144 putative transcriptional regulator YP_001476315.1 KEGG: yen:YE4143 hypothetical protein YP_001476316.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pfo:Pfl_2883 hypothetical protein YP_001476317.1 PFAM: 3-alpha domain protein; MOSC domain containing protein; KEGG: yen:YE4140 hypothetical protein YP_001476318.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE4139 methyl-accepting chemotaxis protein II YP_001476319.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001476320.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001476321.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: ypi:YpsIP31758_4119 aerobic formate dehydrogenase, alpha subunit, proteobacterial-type YP_001476322.1 KEGG: yen:YE4135 formate dehydrogenase-o, major subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001476323.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: ypi:YpsIP31758_4118 putative aerobic formate dehydrogenase, iron-sulfur subunit YP_001476324.1 cytochrome b556(FDO) component; heme containing YP_001476325.1 required for the formation of active formate dehydrogenase YP_001476326.1 KEGG: ypi:YpsIP31758_0230 putative lipoprotein YP_001476327.1 PFAM: Glutathione S-transferase domain; KEGG: ent:Ent638_0139 glutathione S-transferase, C-terminal domain YP_001476328.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001476329.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: yen:YE4130 selenocysteinyl-tRNA-specific translation factor YP_001476330.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_4110 multidrug translocase MdfA YP_001476331.1 KEGG: yen:YE4126 hypothetical protein YP_001476332.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: yen:YE4125 putative transcriptional regulator YP_001476333.1 PFAM: isochorismatase hydrolase; KEGG: yen:YE4124 putative member of isochorismatase hydrolase family YP_001476334.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_001476335.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: yen:YE4123 xylulose kinase YP_001476336.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001476337.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001476338.1 with XylFH is part of the high affinity xylose ABC transporter YP_001476339.1 PFAM: inner-membrane translocator; KEGG: yen:YE4119 sugar transport system permease protein YP_001476340.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypi:YpsIP31758_4098 xylose operon regulatory protein YP_001476341.1 PFAM: DNA polymerase beta domain protein region; KEGG: lpp:plpp0094 hypothetical protein YP_001476342.1 KEGG: lpp:plpp0093 hypothetical protein YP_001476343.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pap:PSPA7_2742 probable transcriptional regulator YP_001476344.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_001476345.1 KEGG: yps:YPTB3589 hypothetical protein YP_001476346.1 PFAM: integrase family protein; KEGG: ypp:YPDSF_3775 phage integrase YP_001476347.1 KEGG: fps:FP1554 hypothetical protein YP_001476348.1 KEGG: sus:Acid_2422 hypothetical protein YP_001476349.1 KEGG: sus:Acid_2423 hypothetical protein YP_001476350.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: syf:Synpcc7942_1725 regulatory protein GntR, HTH YP_001476351.1 KEGG: sun:SUN_0924 acetyltransferase, GNAT family YP_001476352.1 KEGG: ecs:ECs4463 hypothetical protein YP_001476353.1 PFAM: secretion protein HlyD family protein; KEGG: ent:Ent638_0138 secretion protein HlyD family protein YP_001476354.1 PFAM: regulatory protein LuxR; KEGG: ypi:YpsIP31758_0720 transcriptional regulator, LuxR family YP_001476355.1 KEGG: oan:Oant_1359 hypothetical protein YP_001476356.1 KEGG: pat:Patl_3324 hypothetical protein YP_001476357.1 PFAM: histidine triad (HIT) protein; KEGG: har:HEAR2858 conserved hypothetical protein YP_001476358.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: pol:Bpro_4573 transcriptional regulator, LacI family YP_001476359.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: csa:Csal_1758 short-chain dehydrogenase/reductase SDR YP_001476360.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: bte:BTH_II0984 TRAP transporter, DctM subunit subfamily, putative YP_001476361.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: bte:BTH_II0985 bacterial extracellular solute-binding protein, family 7 superfamily YP_001476362.1 KEGG: yen:YE4092 hypothetical protein YP_001476363.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: pfl:PFL_4587 TDP-glucose-4,6-dehydratase-related protein YP_001476364.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bbt:BBta_7356 putative transcriptional regulator, LysR family YP_001476365.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bxe:Bxe_B2157 putative short-chain dehydrogenase/reductase SDR YP_001476366.1 SMART: metal-dependent phosphohydrolase HD region; KEGG: hch:HCH_02572 guanosine polyphosphate pyrophosphohydrolase/synthetases YP_001476367.1 PFAM: regulatory protein MarR; KEGG: sgl:SG0020 transcriptional regulator YP_001476368.1 PFAM: OsmC family protein; KEGG: yen:YE4091 putative osmotic/stress related protein YP_001476369.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001476370.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: ypi:YpsIP31758_4080 transcriptional regulatory protein UhpA YP_001476371.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001476372.1 membrane protein regulates uhpT expression YP_001476373.1 KEGG: gur:Gura_0613 hypothetical protein YP_001476374.1 KEGG: gme:Gmet_2969 hypothetical protein YP_001476375.1 KEGG: sbl:Sbal_3083 chitinase; PFAM: glycoside hydrolase family 18; Chitinase A domain protein; SMART: PKD domain containing protein; chitinase II YP_001476376.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE4083 periplasmic dipeptide transport protein YP_001476377.1 transports peptides consisting of two or three amino acids YP_001476378.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE4081 dipeptide transport system permease protein YP_001476379.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001476380.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001476381.1 KEGG: yen:YE4078 putative inner membrane protein possibly involved in cellulose synthesis YP_001476382.1 KEGG: eca:ECA4365 hypothetical protein YP_001476383.1 KEGG: yen:YE4077 hypothetical protein YP_001476384.1 KEGG: yen:YE4076 hypothetical protein YP_001476385.1 PFAM: YhjQ family protein; KEGG: yen:YE4075 hypothetical protein YP_001476386.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_001476387.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001476388.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001476389.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_001476390.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli YP_001476391.1 involved in the transport of C4-dicarboxylates across the membrane YP_001476392.1 PFAM: peptidase M16 domain protein; KEGG: yen:YE4066 putative insulinase family protease YP_001476393.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: kpn:KPN_04275 peptidyl-prolyl cis-trans isomerase C (rotamase C) YP_001476394.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001476395.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001476396.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001476397.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sdy:SDY_3968 thioredoxin 1 YP_001476398.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001476399.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: ypi:YpsIP31758_0182 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001476400.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001476401.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: yen:YE0171 UDP-N-acetylglucosamine 2-epimerase YP_001476402.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001476403.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_0186 dTDP-glucose 4,6-dehydratase YP_001476404.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: ypi:YpsIP31758_0187 glucose-1-phosphate thymidylyltransferase YP_001476405.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_0188 TDP-D-fucosamine acetyltransferase YP_001476406.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001476407.1 PFAM: polysaccharide biosynthesis protein; KEGG: yen:YE0177 putative lipopolysaccharide biosynthesis protein YP_001476408.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001476409.1 enterobacterial common antigen polymerase YP_001476410.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: ypi:YpsIP31758_0193 glycosyl transferase, WecB/TagA/CpsF family YP_001476411.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001476413.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: yen:YE0184 putative protoheme IX biogenesis protein YP_001476414.1 PFAM: protein of unknown function DUF513 hemX; KEGG: yen:YE0185 putative uroporphyrin-III C-methyltransferase YP_001476415.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001476416.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001476417.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001476418.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001476419.1 KEGG: ypp:YPDSF_3463 lipoprotein YP_001476420.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001476421.1 PFAM: protein of unknown function DUF484; KEGG: ypi:YpsIP31758_0206 hypothetical protein YP_001476422.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001476423.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001476424.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001476425.1 KEGG: kpn:KPN_02730 hypothetical protein YP_001476426.1 responsible for the influx of magnesium ions YP_001476427.1 PFAM: putative ammonia monooxygenase; KEGG: eca:ECA4176 putative membrane protein YP_001476428.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_0215 RarD protein YP_001476429.1 PFAM: thioesterase superfamily protein; KEGG: ypi:YpsIP31758_0216 thioesterase family protein YP_001476430.1 catalyzes the hydrolysis of phosphatidylcholine YP_001476431.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001476432.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: yen:YE0205 threonine efflux protein YP_001476433.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4170 homoserine/homoserine lactone efflux protein YP_001476434.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001476435.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001476436.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001476437.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001476438.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001476439.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001476440.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001476441.1 KEGG: eca:ECA4355 putative lipoprotein YP_001476442.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: yen:YE0216 hypothetical protein YP_001476443.1 PFAM: SirA family protein; KEGG: ypi:YpsIP31758_0232 sulfurtransferase TusA YP_001476444.1 KEGG: plu:plu0508 hypothetical protein YP_001476445.1 KEGG: plu:plu0509 hypothetical protein YP_001476446.1 KEGG: stt:t3689 hypothetical protein YP_001476447.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001476448.1 KEGG: eca:ECA2785 metalloprotease; PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; Peptidase M10 serralysin; SMART: peptidase metallopeptidase YP_001476449.1 PFAM: metalloprotease inhibitor I38; KEGG: pap:PSPA7_4142 alkaline proteinase inhibitor AprI YP_001476450.1 PFAM: YhhN family protein; KEGG: yen:YE0219 hypothetical protein YP_001476451.1 PFAM: regulatory protein LuxR YP_001476452.1 PFAM: CblD family pilus biogenesis initiator protein; KEGG: stt:t2547 putative fimbrail protein YP_001476453.1 KEGG: spt:SPA2453 outermembrane fimbrial usher protein YP_001476454.1 PFAM: CS1 type fimbrial major subunit; KEGG: sec:SC0301 putative fimbrial subunit YP_001476455.1 KEGG: stt:t2550 putative fimbrial protein YP_001476456.1 PFAM: integrase family protein; KEGG: stm:STM0716 putative phage integrase YP_001476457.1 PFAM: protein of unknown function DUF1145; KEGG: yen:YE0223 hypothetical protein YP_001476458.1 catalyzes the methylation of 16S rRNA at position G966 YP_001476459.1 KEGG: yen:YE0225 cell division protein; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001476460.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001476461.1 putative ABC transporter, membrane protein YP_001476462.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001476463.1 KEGG: pen:PSEEN2727 hypothetical protein YP_001476464.1 KEGG: pen:PSEEN2726 hypothetical protein YP_001476465.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB0225 putative acetyltransferase YP_001476466.1 PFAM: Extracellular ligand-binding receptor; KEGG: yen:YE0230 branched-chain amino acid-binding protein YP_001476467.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001476468.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001476469.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001476470.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001476471.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA4336 putative aminotransferase YP_001476472.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001476473.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001476474.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001476475.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001476476.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001476478.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypp:YPDSF_3407 membrane protein YP_001476479.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0262 transcriptional regulator MetR YP_001476480.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001476481.1 PFAM: dienelactone hydrolase; KEGG: ypi:YpsIP31758_0265 dienelactone hydrolase family protein YP_001476482.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001476483.1 KEGG: yen:YE0252 hypothetical protein YP_001476484.1 KEGG: ypi:YpsIP31758_0269 DedA family protein YP_001476485.1 PFAM: protein of unknown function DUF195; KEGG: ypi:YpsIP31758_0270 RmuC domain protein YP_001476486.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001476487.1 PFAM: Sterol-binding domain protein; KEGG: yen:YE0257 hypothetical protein YP_001476488.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001476489.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: plu:plu4410 sec-independent protein translocase protein YP_001476490.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: yps:YPTB0259 sec-independent protein translocase protein TatB YP_001476491.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001476492.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001476493.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001476494.1 TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: eca:ECA0204 transcriptional activator YP_001476495.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001476496.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001476497.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001476498.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001476499.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001476500.1 PFAM: major facilitator superfamily MFS_1; KEGG: aha:AHA_1632 probable MFS transporter YP_001476501.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001476502.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: ypi:YpsIP31758_0285 hypothetical protein YP_001476503.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: yps:YPTB0270 Trk system potassium uptake protein TrkH YP_001476504.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001476505.1 KEGG: eca:ECA0213 UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD linked oxidase domain protein; UDP-N-acetylenolpyruvoylglucosamine reductase domain protein YP_001476506.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001476507.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001476508.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001476509.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001476510.1 Modulates Rho-dependent transcription termination YP_001476511.1 PFAM: ribosomal protein L11; KEGG: sgl:SG0130 50S ribosomal protein L11 YP_001476512.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001476513.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001476514.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001476515.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001476516.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001476517.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001476518.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001476519.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001476520.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis adenylyltransferase YP_001476521.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001476522.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001476523.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001476524.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001476525.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001476526.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001476527.1 PFAM: protein of unknown function DUF416; KEGG: yen:YE0299 hypothetical protein YP_001476528.1 histone-like DNA-binding protein YP_001476529.1 PFAM: protein of unknown function DUF1481; KEGG: yen:YE0301 hypothetical protein YP_001476530.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001476531.1 involved in de novo purine biosynthesis YP_001476532.1 PFAM: coagulation factor 5/8 type domain protein; type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: fno:Fnod_0251 hypothetical protein YP_001476533.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001476534.1 PFAM: protein of unknown function DUF485; KEGG: yen:YE0308 hypothetical protein YP_001476535.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001476536.1 PFAM: sodium:dicarboxylate symporter; KEGG: yen:YE0310 proton glutamate symport protein YP_001476537.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: yen:YE2451 putative lipoprotein YP_001476538.1 PFAM: protein of unknown function DUF81; KEGG: yen:YE3446 hypothetical protein YP_001476539.1 KEGG: eca:ECA0516 hypothetical protein YP_001476540.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: plu:plu1031 unnamed protein product; similar to DNA helicase YP_001476541.1 KEGG: stt:t4228 hypothetical protein YP_001476542.1 KEGG: eca:ECA0552 hypothetical protein YP_001476543.1 KEGG: plu:plu1034 hypothetical protein YP_001476544.1 KEGG: eca:ECA0522A hypothetical protein YP_001476545.1 KEGG: plu:plu1035 hypothetical protein YP_001476546.1 PFAM: Domain of unknown function DUF1845; KEGG: plu:plu1036 hypothetical protein YP_001476548.1 decatenates replicating daughter chromosomes YP_001476549.1 KEGG: plu:plu1038 hypothetical protein YP_001476550.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: yen:YE3844 single-strand binding protein YP_001476551.1 KEGG: ent:Ent638_1532 helix-turn-helix-domain containing protein, AraC type YP_001476553.1 KEGG: dra:DR_1587 hypothetical protein YP_001476554.1 KEGG: mca:MCA0276 killer suppression protein HigA, putative YP_001476555.1 PFAM: protein of unknown function DUF955; KEGG: bxe:Bxe_A0212 hypothetical protein YP_001476556.1 KEGG: bxe:Bxe_A0213 hypothetical protein YP_001476557.1 PFAM: thymidylate synthase; KEGG: bxe:Bxe_A0214 putative thymidylate synthase YP_001476558.1 KEGG: pap:PSPA7_4470 type IV B pilus protein YP_001476559.1 KEGG: stt:t4255 hypothetical protein YP_001476560.1 KEGG: eca:ECA0555 hypothetical protein YP_001476561.1 PFAM: Lytic transglycosylase catalytic; KEGG: eca:ECA0556 hypothetical protein YP_001476562.1 KEGG: eca:ECA0557 hypothetical protein YP_001476563.1 PFAM: restriction endonuclease; KEGG: eca:ECA0558 hypothetical protein YP_001476564.1 KEGG: eca:ECA0560 putative plasmid transfer protein YP_001476565.1 KEGG: eca:ECA0561 hypothetical protein YP_001476566.1 KEGG: eca:ECA0563 hypothetical protein YP_001476567.1 PFAM: plasmid conserved hypothetical protein RAQPRD; KEGG: eca:ECA0564 hypothetical protein YP_001476568.1 KEGG: eca:ECA0565 hypothetical protein YP_001476569.1 KEGG: plu:plu1080 hypothetical protein YP_001476570.1 KEGG: eca:ECA0567 hypothetical protein YP_001476571.1 KEGG: eca:ECA0568 hypothetical protein YP_001476572.1 KEGG: eca:ECA0569 hypothetical protein YP_001476573.1 KEGG: eca:ECA0570 hypothetical protein YP_001476574.1 KEGG: eca:ECA0572 putative lipoprotein YP_001476575.1 KEGG: eca:ECA0573 putative plasmid-related protein YP_001476576.1 KEGG: eca:ECA0574 hypothetical protein YP_001476577.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pst:PSPTO_2960 pyridoxal-phosphate dependent enzyme family/ornithine cyclodeaminase family protein YP_001476578.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: vei:Veis_1206 ornithine cyclodeaminase/mu-crystallin YP_001476579.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: ava:Ava_C0007 condensation domain YP_001476580.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: bce:BC2456 peptide synthetase YP_001476581.1 PFAM: Thioesterase; KEGG: bte:BTH_I2357 thioesterase type II YP_001476582.1 PFAM: phosphoribosylglycinamide synthetase; KEGG: ypm:YP_3384 acetyl-CoA carboxylase YP_001476584.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: sus:Acid_4624 asparagine synthase (glutamine-hydrolyzing) YP_001476585.1 KEGG: bja:blr2082 hypothetical protein YP_001476586.1 PFAM: protein of unknown function DUF1525; KEGG: eca:ECA0576 hypothetical protein YP_001476587.1 PFAM: protein of unknown function DUF1527; KEGG: eca:ECA0577 hypothetical protein YP_001476588.1 KEGG: eca:ECA0578 hypothetical protein YP_001476589.1 KEGG: eca:ECA0579 hypothetical protein YP_001476590.1 KEGG: eca:ECA0580 hypothetical protein YP_001476591.1 KEGG: eca:ECA0581 hypothetical protein YP_001476592.1 KEGG: osa:4352161 Os12g0450200 YP_001476593.1 KEGG: kpn:KPN_pKPN3p05885 transposase YP_001476594.1 PFAM: Integrase catalytic region; KEGG: bvi:Bcep1808_7234 integrase, catalytic region YP_001476595.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pst:PSPTO_B0039 transposase/IS protein YP_001476596.1 PFAM: transposase Tn3 family protein; KEGG: ent:Ent638_4224 transposase Tn3 family protein YP_001476597.1 PFAM: transposase IS3/IS911 family protein; KEGG: pae:PA0983 hypothetical protein YP_001476598.1 PFAM: DinB family protein; KEGG: eca:ECA0612 hypothetical protein YP_001476599.1 KEGG: sen:SACE_4169 esterase/lipase YP_001476600.1 PFAM: regulatory protein TetR; KEGG: fal:FRAAL5169 putative TetR-family transcriptional regulator YP_001476601.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ypi:YpsIP31758_2550 paraquat-inducible protein A YP_001476602.1 PFAM: Mammalian cell entry related domain protein; KEGG: yen:YE1574 putative paraquat-inducible protein B YP_001476603.1 PFAM: protein of unknown function DUF330; KEGG: yen:YE1575 putative lipoprotein protein YP_001476604.1 PFAM: plasmid conserved hypothetical protein RAQPRD; KEGG: eca:ECA0564 hypothetical protein YP_001476605.1 KEGG: ppu:PP_5396 ISPpu14, transposase Orf3 YP_001476607.1 KEGG: pfl:PFL_2517 hypothetical protein YP_001476608.1 KEGG: rha:RHA1_ro01207 hypothetical protein YP_001476609.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: psp:PSPPH_3647 lipase YP_001476610.1 PFAM: regulatory protein MarR; KEGG: sfr:Sfri_0578 transcriptional regulator, MarR family protein YP_001476611.1 PFAM: transposase IS3/IS911 family protein; KEGG: yen:YE1810 insertion element protein YP_001476612.1 PFAM: Integrase catalytic region; KEGG: sec:SC173 hypothetical protein B YP_001476613.1 PFAM: Catalase domain protein; KEGG: bch:Bcen2424_3898 catalase YP_001476614.1 PFAM: Ankyrin; KEGG: xcb:XC_4036 ankyrin-like protein YP_001476615.1 KEGG: kpn:KPN_pKPN5p08239 hypothetical protein YP_001476617.1 PFAM: Resolvase domain; KEGG: psp:PSPPH_A0101 DNA invertase YP_001476618.1 TIGRFAM: YD repeat protein; KEGG: sbm:Shew185_0579 YD repeat protein YP_001476620.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: xfa:XF1743 esterase YP_001476621.1 KEGG: sco:SCO7479 integral membrane protein YP_001476622.1 KEGG: psp:PSPPH_B0058 site-specific recombinase, phage integrase family YP_001476623.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001476624.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001476626.1 KEGG: plu:plu1152 hypothetical protein YP_001476627.1 KEGG: sty:HCM2.0043 hypothetical protein YP_001476630.1 KEGG: stt:t4289 hypothetical protein YP_001476631.1 PFAM: domain of unknown function DUF1738; KEGG: yen:YE3460 hypothetical protein YP_001476632.1 KEGG: yen:YE3459 hypothetical protein YP_001476633.1 PFAM: protein of unknown function DUF1281; KEGG: ypi:YpsIP31758_3689 hypothetical protein YP_001476634.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_2523 oxidoreductase, short chain dehydrogenase/reductase family protein YP_001476635.1 PFAM: regulatory protein LuxR; KEGG: asa:ASA_P5G023 hypothetical protein YP_001476636.1 PFAM: protein of unknown function DUF1528; Relaxase; KEGG: eca:ECA0613 hypothetical protein YP_001476637.1 PFAM: integrase family protein; KEGG: plu:plu1166 hypothetical protein YP_001476638.1 PFAM: regulatory protein TetR; KEGG: ypk:y0598 hypothetical protein YP_001476639.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001476640.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001476641.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001476642.1 catalyzes the formation of fumarate from aspartate YP_001476643.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: yen:YE0352 hypothetical protein YP_001476644.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001476645.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; KEGG: stm:STM4330 chaperone Hsp60 with peptide-dependent ATPase activity, affects cell division YP_001476646.1 KEGG: ypi:YpsIP31758_3674 hypothetical protein YP_001476647.1 KEGG: yen:YE0356 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001476648.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001476649.1 PFAM: Entericidin EcnAB; KEGG: sec:SC4214 putative entericidin A precursor YP_001476650.1 PFAM: Entericidin EcnAB; KEGG: eca:ECA3975 entericidin B YP_001476651.1 PFAM: small multidrug resistance protein; KEGG: stm:STM4338 putative DMT superfamily transport protein YP_001476652.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001476653.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001476654.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001476655.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001476656.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001476657.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ypi:YpsIP31758_3664 mechanosensitive ion channel domain protein YP_001476658.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001476659.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001476660.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001476661.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: eca:ECA3940 putative 4Fe-4S binding protein YP_001476662.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: yen:YE0372 hypothetical protein YP_001476663.1 possibly involved in cell wall synthesis YP_001476664.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: yen:YE0374 putative N-acetylmuramoyl-L-alanine amidase-family protein YP_001476665.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001476666.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001476667.1 Stimulates the elongation of poly(A) tails YP_001476668.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001476669.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001476670.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001476671.1 KEGG: ypi:YpsIP31758_3649 hypothetical protein YP_001476672.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001476673.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001476674.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001476675.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001476676.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001476677.1 PFAM: protein of unknown function DUF350; KEGG: eca:ECA3620 hypothetical protein YP_001476678.1 PFAM: protein of unknown function DUF1471; KEGG: ent:Ent638_0367 protein of unknown function DUF1471 YP_001476679.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001476680.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001476681.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE0389 hypothetical protein YP_001476682.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001476683.1 binds single-stranded DNA at the primosome assembly site YP_001476684.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001476685.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001476686.1 PFAM: protein of unknown function DUF488; KEGG: yen:YE2509 hypothetical protein YP_001476687.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: yen:YE0397 hypothetical protein YP_001476688.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001476689.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001476690.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001476691.1 PFAM: conserved hypothetical protein; KEGG: yen:YE0401 hypothetical protein YP_001476692.1 PFAM: protein of unknown function DUF1107; KEGG: ent:Ent638_0395 protein of unknown function DUF1107 YP_001476693.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ypi:YpsIP31758_3627 CBS/transporter associated domain protein YP_001476694.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001476695.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: ypi:YpsIP31758_3625 surface antigen/outer membrane protein, OMP85 family YP_001476696.1 PFAM: protein of unknown function DUF490; KEGG: yen:YE0406 hypothetical protein YP_001476697.1 PFAM: AIG2 family protein; KEGG: yen:YE0407 hypothetical protein YP_001476698.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001476699.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE0409 methyl-accepting chemotaxis protein YP_001476700.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001476701.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: yps:YPTB0457 UDP-N-acetylmuramate:L-Ala-D-Glu-meso- diaminopime late ligase YP_001476702.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE0412 hypothetical protein YP_001476703.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE0412 hypothetical protein YP_001476704.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001476705.1 oxidizes malate to oxaloacetate YP_001476706.1 KEGG: ypi:YpsIP31758_3615 sugar fermentation stimulation protein B YP_001476707.1 KEGG: ypi:YpsIP31758_3614 hypothetical protein YP_001476708.1 PFAM: Polyprenyl synthetase; KEGG: eca:ECA0689 octaprenyl-diphosphate synthase YP_001476709.1 PFAM: ribosomal protein L21; KEGG: eca:ECA0690 50S ribosomal protein L21 YP_001476710.1 involved in the peptidyltransferase reaction during translation YP_001476711.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_3610 integral membrane protein YP_001476712.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001476713.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE0422 two-component system sensor protein YP_001476714.1 response regulator in two-component regulatory system with BasS YP_001476715.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001476716.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: yen:YE0425 transcription elongation factor YP_001476717.1 PFAM: protein of unknown function UPF0044; KEGG: stm:STM3298.S putative RNA-binding protein YP_001476718.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001476719.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001476720.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001476721.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001476722.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: yen:YE0431 protein-export membrane protein YP_001476723.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001476724.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001476725.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001476726.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001476727.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001476728.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001476729.1 KEGG: yen:YE0438 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001476730.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001476731.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001476732.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: ypi:YpsIP31758_3810 YeeE/YedE family protein YP_001476733.1 PFAM: SirA family protein; KEGG: net:Neut_1003 SirA family protein YP_001476734.1 PFAM: luciferase family protein; KEGG: yen:YE0442 hypothetical protein YP_001476735.1 PFAM: secretion protein HlyD family protein; KEGG: plu:plu4516 unnamed protein product; highly similar to membrane fusion protein (MFP) of ABC transport system YP_001476736.1 PFAM: ABC-2 type transporter; KEGG: plu:plu4515 unnamed protein product; similar to permease protein of ABC transport system YP_001476737.1 PFAM: ABC-2 type transporter; KEGG: plu:plu4514 unnamed protein product; similar to permease protein of ABC transport system YP_001476738.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: ent:Ent638_0491 cupin 4 family protein YP_001476739.1 PFAM: peptidase U32; KEGG: yen:YE0449 hypothetical protein YP_001476740.1 PFAM: peptidase U32; KEGG: ent:Ent638_3595 peptidase U32 YP_001476741.1 PFAM: Sterol-binding domain protein; KEGG: yen:YE0451 putative lipid carrier protein YP_001476742.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE0452 putative acetyltransferase YP_001476743.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: yen:YE0453 hypothetical protein YP_001476744.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001476745.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: yen:YE0455 ornithine decarboxylase, inducible YP_001476746.1 KEGG: ypp:YPDSF_3277 hypothetical protein YP_001476747.1 KEGG: ypi:YpsIP31758_3569 hypothetical protein YP_001476748.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001476749.1 KEGG: rpe:RPE_3116 putative acetyltransferase (virginiamycin, streptogramin A, chloramphenicol) YP_001476750.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ypi:YpsIP31758_3567 putative phosphonate metabolism ribose 1,5-bisphosphokinase PhnN YP_001476751.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ypn:YPN_0624 PhnM protein YP_001476752.1 KEGG: ypp:YPDSF_3272 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_001476753.1 KEGG: yen:YE0473 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_001476754.1 PFAM: phosphonate metabolism PhnJ; KEGG: ypi:YpsIP31758_3563 phosphonate metabolism protein PhnJ YP_001476755.1 PFAM: phosphonate metabolism; KEGG: ypi:YpsIP31758_3562 phosphonate metabolism protein PhnI YP_001476756.1 PFAM: phosphonate metabolism; KEGG: yen:YE0476 PhnH protein YP_001476757.1 PFAM: phosphonate metabolism PhnG; KEGG: yen:YE0477 PhnG protein YP_001476758.1 may be involved in phosphonate uptake and biodegradation YP_001476759.1 PFAM: permease; KEGG: ssn:SSON_3297 hypothetical protein YP_001476760.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001476761.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001476762.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE0483 putative LysR-family transcriptional regulatory protein YP_001476763.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: yen:YE0484 putative oxidoreductase YP_001476764.1 KEGG: yen:YE3773 putative trehalose-6-phosphate hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_001476765.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001476766.1 KEGG: ssn:SSON_PB07 entry exclusion protein 2 YP_001476767.1 PFAM: Colicin D; KEGG: ypm:YP_3568 putative colicin immunity protein YP_001476768.1 PFAM: S-type Pyocin domain protein; KEGG: pap:PSPA7_3037 killer protein of pyocin S3 YP_001476769.1 KEGG: sgl:SG1235 hypothetical protein YP_001476770.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001476771.1 P-type ATPase involved in magnesium influx YP_001476772.1 PFAM: Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, catalytic core; KEGG: ent:Ent638_0442 beta-N-acetylhexosaminidase YP_001476773.1 PFAM: 20S proteasome A and B subunits; KEGG: yen:YE3772 hypothetical protein YP_001476774.1 PFAM: transglutaminase domain protein; transglutaminase domain protein; KEGG: yen:YE3771 hypothetical protein YP_001476775.1 PFAM: protein of unknown function DUF403; KEGG: yen:YE3770 hypothetical protein YP_001476776.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: yen:YE3769 hypothetical protein YP_001476777.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: yen:YE3768 hypothetical protein YP_001476778.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001476779.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001476780.1 PFAM: transport system permease protein; KEGG: eca:ECA4256 putative iron(III) ABC transporter permease protein YP_001476781.1 PFAM: periplasmic binding protein; KEGG: eca:ECA4255 putative iron(III) ABC transporter, periplasmic-binding protein YP_001476782.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA4254 putative iron(III) ABC transporter ATP-binding protein YP_001476783.1 KEGG: kpn:KPN_04792 hypothetical protein YP_001476784.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: kpn:KPN_04798 putative transcriptional regulator (N-terminal); putative sugar-binding domain of regulator protein (C-terminal) YP_001476785.1 PFAM: amidohydrolase; D-aminoacylase domain protein; Amidohydrolase 3; KEGG: kpn:KPN_04793 hypothetical protein YP_001476786.1 PFAM: Endoribonuclease L-PSP; KEGG: kpn:KPN_04794 hypothetical protein YP_001476787.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE0491 ABC transporter, substrate binding protein YP_001476788.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: yen:YE0494 ornithine carbamoyltransferase chain I YP_001476789.1 PFAM: protein of unknown function DUF1260; KEGG: yen:YE0495 hypothetical protein YP_001476790.1 PFAM: tRNA--hydroxylase; KEGG: ent:Ent638_0461 tRNA--hydroxylase YP_001476791.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: bte:BTH_II0331 GMC oxidoreductase YP_001476792.1 PFAM: acyltransferase 3; KEGG: apl:APL_1465 hypothetical protein YP_001476793.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypp:YPDSF_3254 acetyltransferase YP_001476794.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001476795.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001476796.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001476797.1 PFAM: permease YjgP/YjgQ family protein; KEGG: ypi:YpsIP31758_3542 putative permease YP_001476798.1 PFAM: permease YjgP/YjgQ family protein; KEGG: yen:YE0502 hypothetical protein YP_001476799.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: shn:Shewana3_2962 filamentation induced by cAMP protein Fic YP_001476800.1 PFAM: carbonic anhydrase; KEGG: kpn:KPN_02014 putative carbonic anhydrase YP_001476801.1 PFAM: helix-turn-helix domain protein; KEGG: ent:Ent638_2034 putative transcriptional regulator, XRE family YP_001476802.1 KEGG: kpn:KPN_04693 hypothetical protein YP_001476804.1 PFAM: ATP-binding region ATPase domain protein; KEGG: azo:azo0358 putative two-component sensor kinase YP_001476805.1 PFAM: Restriction endonuclease EcoRII; KEGG: acr:Acry_3581 hypothetical protein YP_001476806.1 PFAM: DNA mismatch endonuclease vsr; KEGG: plu:plu0339 very short patch repair protein (DNA mismatch endonuclease) (Vsr mismatch endonuclease) (V.EcoKDcm) YP_001476807.1 KEGG: plu:plu0338 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001476808.1 KEGG: eca:ECA0128 hypothetical protein YP_001476809.1 PFAM: glycoside hydrolase family 1; KEGG: sdy:SDY_2912 6-phospho-beta-glucosidase YP_001476810.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001476811.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ent:Ent638_3187 regulatory protein, LacI YP_001476812.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: mmw:Mmwyl1_0262 transcriptional regulator, AraC family YP_001476813.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: mmw:Mmwyl1_0263 drug resistance transporter, Bcr/CflA subfamily YP_001476814.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: eca:ECA1189 hypothetical protein YP_001476815.1 PFAM: protein of unknown function DUF466; KEGG: eca:ECA1188 hypothetical protein YP_001476816.1 PFAM: carbon starvation protein CstA; KEGG: eca:ECA1187 putative carbon starvation protein YP_001476817.1 PFAM: glycosyl transferase family 20; KEGG: pol:Bpro_3918 alpha,alpha-trehalose-phosphate synthase YP_001476818.1 PFAM: glutamine synthetase catalytic region; KEGG: kpn:KPN_01021 putative glutamine synthetase YP_001476819.1 KEGG: pap:PSPA7_2489 hypothetical protein YP_001476820.1 KEGG: kpn:KPN_01908 putative receptor YP_001476822.1 KEGG: stt:t4360 hypothetical protein YP_001476823.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02052 putative transcriptional regulator (LysR family) YP_001476824.1 KEGG: pap:PSPA7_3295 probable CoA transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001476825.1 KEGG: pap:PSPA7_3294 probable CoA transferase, subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001476826.1 KEGG: ppu:PP_4636 beta-ketothiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001476827.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: kpn:KPN_02056 3-hydroxybutyryl-CoA dehydrogenase YP_001476828.1 PFAM: Citrate transporter; KEGG: pfl:PFL_3575 hypothetical protein YP_001476829.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001476830.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_3814 helix-turn-helix-domain containing protein AraC type YP_001476831.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: yen:YE0593 putative right origin-binding protein YP_001476832.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sgl:SG1042 hypothetical protein YP_001476833.1 PFAM: putative transposase YhgA family protein; KEGG: stm:PSLT051 putative cytoplasmic protein YP_001476834.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: eca:ECA0929 biopolymer transport protein YP_001476835.1 TIGRFAM: TonB family protein; KEGG: eca:ECA0928 TonB-like protein YP_001476836.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA0927 TonB-dependent receptor YP_001476837.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: eca:ECA0926 putative biopolymer transport protein YP_001476838.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: eca:ECA0925 putative phospholipase YP_001476839.1 PFAM: peptidase S58 DmpA; KEGG: pfo:Pfl_3533 peptidase S58, DmpA YP_001476840.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: aav:Aave_4746 methylmalonate-semialdehyde dehydrogenase YP_001476841.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001476842.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rfr:Rfer_0374 transcriptional regulator, LysR family YP_001476843.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001476844.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001476845.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: cte:CT0951 alcohol dehydrogenase, iron-containing YP_001476846.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: plu:plu4288 hypothetical protein YP_001476847.1 PFAM: FAD dependent oxidoreductase; KEGG: plu:plu4287 unnamed protein product; highly similar to probable oxidoreductase YP_001476848.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: plu:plu4286 hypothetical protein YP_001476849.1 PFAM: alpha/beta hydrolase fold; KEGG: sco:SCO6966 lipase YP_001476850.1 PFAM: histone deacetylase superfamily; KEGG: kpn:KPN_00530 putative deacetylase YP_001476851.1 PFAM: major facilitator superfamily MFS_1; KEGG: pau:PA14_15270 putative permease YP_001476852.1 PFAM: regulatory protein LuxR; KEGG: plu:plu4274 hypothetical protein YP_001476853.1 PFAM: amino acid permease-associated region; KEGG: plu:plu4273 hypothetical protein YP_001476854.1 KEGG: plu:plu4272 hypothetical protein YP_001476855.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_00526 putative 3-ketoacyl-(acyl-carrier-protein) reductase YP_001476856.1 KEGG: bpm:BURPS1710b_A2463 MoaF YP_001476857.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001476858.1 TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; KEGG: plu:plu0991 homoprotocatechuate degradation operon regulator YP_001476859.1 KEGG: plu:plu0990 hypothetical protein; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase YP_001476860.1 KEGG: plu:plu0989 similar to C-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)]; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG2 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase YP_001476861.1 TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: kpn:KPN_04787 4-hydroxyphenylacetate catabolism YP_001476862.1 KEGG: kpn:KPN_04786 4-hydroxyphenylacetate catabolism; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B YP_001476863.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: plu:plu0986 5-carboxymethyl-2-hydroxy-muconic acid isomerase YP_001476864.1 KEGG: ssn:SSON_4495 2-oxo-hept-3-ene-1,7-dioate hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase YP_001476865.1 KEGG: ssn:SSON_4494 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (HHED aldolase); TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase YP_001476866.1 TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4406 putative 4-hydroxyphenylacetate permease YP_001476867.1 TIGRFAM: 4-hydroxyphenylacetate catabolism regulatory protein HpaA; PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: kpn:KPN_04781 4-hydroxyphenylacetate catabolism YP_001476868.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: stm:STM1099 4-hydroxyphenylacetate catabolism YP_001476869.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: plu:plu0974 4-hydroxyphenylacetic acid hydroxylase YP_001476870.1 this protein has no known enzymatic function YP_001476871.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: bvi:Bcep1808_3378 GntR domain protein YP_001476872.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_2412 oxidoreductase, short chain dehydrogenase/reductase family protein YP_001476873.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ypi:YpsIP31758_2411 fumarylacetoacetate hydrolase family protein YP_001476874.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ypi:YpsIP31758_2410 mandelate racemase/muconate lactonizing enzyme family protein YP_001476875.1 PFAM: amidohydrolase 2; KEGG: bvi:Bcep1808_3379 amidohydrolase 2 YP_001476876.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bvi:Bcep1808_3383 short-chain dehydrogenase/reductase SDR YP_001476877.1 KEGG: rfr:Rfer_3138 hypothetical protein YP_001476878.1 TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cff:CFF8240_1066 L-fucose:H+ symporter permease YP_001476879.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: yen:YE0557 HmsT protein YP_001476880.1 PFAM: protein of unknown function DUF1435; KEGG: eca:ECA0738 hypothetical protein YP_001476881.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE0559 LysR-family regulatory protein YP_001476882.1 PFAM: aldo/keto reductase; KEGG: eca:ECA0736 putative aldo/keto reductase YP_001476883.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001476884.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001476885.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001476886.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001476887.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ypi:YpsIP31758_3503 osmotically induced periplasmic protein OsmY YP_001476888.1 PFAM: protein of unknown function DUF1328; KEGG: kpn:KPN_04833 putative amino acid/amine transport protein YP_001476889.1 KEGG: eca:ECA0471 hypothetical protein YP_001476890.1 PFAM: Patatin; KEGG: yen:YE0567 hypothetical protein YP_001476891.1 PFAM: TatD-related deoxyribonuclease; KEGG: ypp:YPDSF_3199 metalloenzyme YP_001476892.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: ecv:APECO1_2528 hypothetical protein YP_001476893.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ypm:YP_3746 putative Na+ dependent nucleosidetransporter-family protein YP_001476894.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001476895.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001476896.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001476897.1 TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: yen:YE0574 purine nucleoside phosphorylase YP_001476898.1 PFAM: HipA domain protein; KEGG: yen:YE0575 putative DNA-binding protein YP_001476899.1 KEGG: yps:YPTB0585 membrane protein, transcribed divergently from SerB YP_001476900.1 catalyzes the formation of serine from O-phosphoserine YP_001476901.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001476902.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001476903.1 TIGRFAM: Alcohol dehydrogenase. zinc-binding type 1; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: yen:YE0581 putative oxidoreductase YP_001476904.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE0582 putative LysR-family transcriptional regulatory protein YP_001476905.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001476906.1 PFAM: OmpA/MotB domain protein; KEGG: ypi:YpsIP31758_3488 OmpA family protein YP_001476907.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: yen:YE0586 hypothetical protein YP_001476908.1 KEGG: yen:YE0587 hypothetical protein YP_001476909.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001476910.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001476911.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001476912.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001476913.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: yen:YE0593 putative right origin-binding protein YP_001476914.1 PFAM: CreA family protein; KEGG: ypi:YpsIP31758_3479 CreA protein YP_001476915.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE0595 aerobic respiration control protein YP_001476916.1 member of the SPOUT superfamily of methyltransferases YP_001476917.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001476918.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001476919.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001476920.1 PFAM: protein of unknown function DUF328; KEGG: yen:YE0603 hypothetical protein YP_001476921.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: plu:plu2791 unnamed protein product; highly similar to probable amino acid transport protein YaaJ, sodium-dependent of Escherichia coli YP_001476922.1 KEGG: yen:YE0604 transaldolase B; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001476923.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001476924.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE0606 putative transport protein YP_001476925.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: yen:YE0608 hypothetical protein YP_001476926.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001476927.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001476928.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001476929.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001476930.1 PFAM: ribosomal protein S20; KEGG: eca:ECA3878 30S ribosomal protein S20 YP_001476931.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001476932.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001476933.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001476934.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ypp:YPDSF_3155 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001476935.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001476936.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pmy:Pmen_0810 transcriptional regulator, LysR family YP_001476937.1 PFAM: Pyoverdine biosynthesis protein; KEGG: eca:ECA3381 pyoverdine biosynthesis protein YP_001476938.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA; KEGG: eca:ECA3380 pyoverdine biosynthesis protein YP_001476939.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: glycosyl transferase family 28; KEGG: eca:ECA3379 putative glycosyltransferase YP_001476940.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bxe:Bxe_A0545 putative short-chain dehydrogenase/reductase, FabG-like YP_001476941.1 PFAM: dihydrodipicolinate synthetase; KEGG: vvy:VVA1582 putative dihydrodipicolinate synthase YP_001476942.1 KEGG: vvy:VVA1581 putative dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_001476943.1 PFAM: major facilitator superfamily MFS_1; KEGG: rso:RSc2352 probable permease transmembrane protein YP_001476944.1 KEGG: ecs:ECs3819 galactose-proton symport of transport system; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001476945.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: vvy:VVA1573 hypothetical protein YP_001476946.1 PFAM: dihydrodipicolinate reductase; KEGG: eca:ECA3872 dihydrodipicolinate reductase YP_001476947.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001476948.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001476949.1 Required for full activity of KefC, a potassium-proton antiporter YP_001476950.1 transport system that facilitates potassium-efflux YP_001476951.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA3867 putative LysE-type translocator YP_001476952.1 PFAM: protein of unknown function DUF1212; KEGG: yps:YPTB0626 putative transmembrane protein YP_001476953.2 KEGG: ypi:YpsIP31758_3450 hypothetical protein YP_001476954.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001476955.1 PFAM: protein of unknown function DUF839; KEGG: pfl:PFL_5696 Tat (twin-arginine translocation) pathway signal sequence domain protein YP_001476956.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001476957.1 protein associated with Co2+ and Mg2+ efflux YP_001476958.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001476959.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001476960.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001476961.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001476962.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001476963.1 PFAM: pseudouridine synthase; KEGG: eca:ECA3854 ribosomal large subunit pseudouridine synthase A YP_001476964.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001476965.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001476966.1 PFAM: SNARE associated Golgi protein; KEGG: yen:YE0639 putative DedA-family membrane protein YP_001476967.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001476968.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: eca:ECA3848 acetolactate synthase isozyme I large subunit YP_001476969.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001476970.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001476971.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001476972.1 activates sgrS under glucose-phosphate stress conditions YP_001476974.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE0648 sugar efflux transporter YP_001476975.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rfr:Rfer_1465 anion transporter YP_001476976.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001476977.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001476978.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001476979.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001476980.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001476981.1 PFAM: AMP-dependent synthetase and ligase; KEGG: ypi:YpsIP31758_3402 AMP binding protein YP_001476982.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001476983.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001476984.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001476985.1 PFAM: protein of unknown function DUF1144; KEGG: ypi:YpsIP31758_3397 hypothetical protein YP_001476986.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001476987.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: ypi:YpsIP31758_3395 S-adenosyl-methyltransferase MraW YP_001476988.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001476989.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: yen:YE0666 penicillin-binding protein 3 YP_001476990.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001476991.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: ypp:YPDSF_3091 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate--D-alanyl-D-alanyl ligase YP_001476992.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001476993.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001476994.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001476995.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001476996.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001476997.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001476998.1 involved in septum formation YP_001476999.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001477000.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001477001.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001477002.1 KEGG: ypi:YpsIP31758_3380 hypothetical protein YP_001477003.1 secM translational pause allows for the initiation of secA translation YP_001477004.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001477005.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: yen:YE0682 mutator protein MutT YP_001477006.1 PFAM: protein of unknown function DUF329; KEGG: ecc:c0121 zinc-binding protein YP_001477007.1 PFAM: protein of unknown function DUF1342; KEGG: yen:YE0684 hypothetical protein YP_001477008.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001477009.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001477010.1 PFAM: type II secretion system protein; KEGG: ypi:YpsIP31758_3372 putative protein transport protein HofC YP_001477011.1 PFAM: type II secretion system protein E; KEGG: eca:ECA3799 protein transport protein YP_001477012.1 KEGG: yen:YE0690 putative prepilin peptidase dependent protein D precursor YP_001477013.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001477014.1 involved in regulation of beta-lactamase; putative signaling protein YP_001477015.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001477016.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001477017.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: ent:Ent638_0696 iron-sulfur cluster assembly accessory protein YP_001477018.1 KEGG: eca:ECA3305 putative lipoprotein YP_001477019.1 PFAM: protein of unknown function UPF0126; KEGG: yen:YE0737 hypothetical protein YP_001477020.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001477021.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001477022.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001477023.1 protease Do; required at high temperature; degrades damaged proteins YP_001477024.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001477025.1 KEGG: pmy:Pmen_1734 RNA methyltransferase, TrmA family YP_001477026.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001477027.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001477028.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001477029.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001477030.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pap:PSPA7_2666 hypothetical protein YP_001477031.1 KEGG: pfl:PFL_1327 hypothetical protein YP_001477032.1 KEGG: pfl:PFL_3514 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Aluminium resistance family protein YP_001477033.1 KEGG: psb:Psyr_4832 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase YP_001477034.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pae:PA5094 putative glycine betaine/proline transport system ATP-binding protein YP_001477035.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pau:PA14_67280 putative amino acid transporter permease protein YP_001477036.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: pfo:Pfl_0362 substrate-binding region of ABC-type glycine betaine transport system YP_001477037.1 PFAM: amino acid permease-associated region; KEGG: yen:YE4093 amino acid permease YP_001477038.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001477039.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001477041.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: reh:H16_B2293 4-hydroxybenzoate transporter, MFS-type AAHS family YP_001477042.1 PFAM: Radical SAM domain protein; KEGG: ypi:YpsIP31758_3313 radical SAM domain protein YP_001477043.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ypi:YpsIP31758_3312 putative 6-pyruvoyl tetrahydrobiopterin synthase YP_001477044.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001477045.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001477046.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001477047.1 KEGG: asa:ASA_P5G104 hypothetical protein YP_001477048.1 KEGG: yen:YE0485 hypothetical protein YP_001477049.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_001477051.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: yen:YE0761 siroheme synthase YP_001477052.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001477053.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001477054.1 PFAM: adenylylsulfate kinase; KEGG: yps:YPTB0767 adenylylsulfate kinase YP_001477055.1 KEGG: yen:YE0766 hypothetical protein YP_001477056.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3539 amino acid ABC transporter, ATP-binding protein YP_001477057.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3538 amino acid ABC transporter YP_001477058.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: eca:ECA3537 amino acid-binding protein YP_001477059.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001477060.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: ypi:YpsIP31758_3299 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001477061.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001477062.1 catalyzes the modification of U13 in tRNA(Glu) YP_001477063.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001477064.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001477065.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001477066.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001477067.1 This protein performs the mismatch recognition step during the DNA repair process YP_001477068.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001477069.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001477070.1 PFAM: glycoside hydrolase family 1; KEGG: yen:YE0969 putative glycosyl hydrolase YP_001477071.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001477072.1 PFAM: YdjC family protein; KEGG: ypi:YpsIP31758_1095 UPF0249 protein ChbG YP_001477073.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE0827 hypothetical protein YP_001477074.1 PFAM: CinA domain protein; KEGG: ypi:YpsIP31758_3241 competence/damage-inducible protein CinA domain protein YP_001477075.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001477076.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001477077.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001477078.1 PFAM: carbon storage regulator; KEGG: plu:plu1251 carbon storage regulator homolog YP_001477079.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001477080.1 KEGG: yen:YE0837 hypothetical protein YP_001477081.1 involved in the first step of glutathione biosynthesis YP_001477082.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001477083.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: yen:YE0840 hypothetical protein YP_001477084.1 PFAM: cytochrome c assembly protein; KEGG: yps:YPTB0832 hypothetical protein YP_001477085.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001477086.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001477087.1 Essential for efficient processing of 16S rRNA YP_001477088.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001477089.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001477090.1 PFAM: transcriptional activator Ogr/delta; KEGG: ecv:APECO1_14 Ogr YP_001477091.1 PFAM: late control D family protein; KEGG: yps:YPTB1739 similar to D protein bacteriophage 186 and P2 YP_001477092.1 PFAM: P2 GpU family protein; KEGG: yps:YPTB1740 putative phage tail protein YP_001477093.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: ent:Ent638_1357 phage tail-like protein YP_001477094.1 PFAM: P2 GpE family protein; KEGG: kpn:KPN_04861 putative prophage tail protein YP_001477095.1 PFAM: tail E family protein; KEGG: yps:YPTB1743 putative tail protein gpE P2 bacteriophage YP_001477096.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: yps:YPTB1744 putative tail tube protein FII (bacteriophage P2) YP_001477097.1 PFAM: tail sheath protein; KEGG: yps:YPTB1745 putative tail sheath protein (P2 and 186 bacteriophage) YP_001477098.1 PFAM: tail assembly chaperone gp38; KEGG: sgl:SG0710 hypothetical protein YP_001477099.1 PFAM: tail fiber repeat 2 protein; KEGG: plu:plu0021 hypothetical protein YP_001477100.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: yen:YE1663 phage tail protein YP_001477101.1 PFAM: Baseplate J family protein; KEGG: yps:YPTB1749 probable bacteriophage protein YP_001477102.1 PFAM: GPW/gp25 family protein; KEGG: yps:YPTB1750 possible phage-related protein YP_001477103.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: yps:YPTB1751 putative phage-related baseplate assembly protein YP_001477104.1 PFAM: P2 phage tail completion R family protein; KEGG: yps:YPTB1850 gpR [Enterobacteria phage P2] YP_001477105.1 PFAM: glycoside hydrolase family 24; KEGG: yps:YPTB1755 putative phage lysozyme YP_001477106.1 KEGG: yps:YPTB1756 putative prophage Hp1 family holin YP_001477107.1 PFAM: tail X family protein; KEGG: yps:YPTB1757 putative phage-related tail protein YP_001477108.1 PFAM: replication gene A; KEGG: ecv:APECO1_4464 putative phage replication initiation protein YP_001477109.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: yen:YE1687 hypothetical 8.2 kDa protein in gpa 5'region YP_001477110.1 KEGG: yps:YPTB1768 similar to gpB bacteriophage P2 YP_001477111.1 PFAM: CI repressor; KEGG: ecc:c0934 hypothetical protein YP_001477112.1 PFAM: protein of unknown function DUF481; KEGG: ypi:YpsIP31758_3223 hypothetical protein YP_001477113.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001477114.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001477115.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001477116.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: ypi:YpsIP31758_3216 ribosomal subunit interface protein YP_001477117.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001477118.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001477119.1 PFAM: protein of unknown function DUF152; KEGG: yen:YE0892 hypothetical protein YP_001477120.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: yen:YE0893 Clp ATPase YP_001477121.1 KEGG: yen:YE0895 putative lipoprotein YP_001477122.1 KEGG: yen:YE0896 hypothetical protein YP_001477123.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: yen:YE0897 putative acyltransferase YP_001477124.1 KEGG: yen:YE0898 putative acyl carrier protein YP_001477125.1 carries the fatty acid chain in fatty acid biosynthesis YP_001477126.1 KEGG: yen:YE0900 putative inner membrane protein YP_001477127.1 KEGG: yen:YE0901 putative AMP-binding protein YP_001477128.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: yen:YE0902 putative dehydratase YP_001477129.1 PFAM: glycosyl transferase family 2; KEGG: yen:YE0903 putative bifunctional glycosyl transferase/acyl transferase YP_001477130.1 PFAM: thioesterase superfamily protein; KEGG: yen:YE0904 putative thioesterase YP_001477131.1 KEGG: yen:YE0905 putative outer-membrane lipoprotein carrier protein YP_001477132.1 KEGG: yen:YE0906 putative inner membrane protein YP_001477133.1 KEGG: yen:YE0907 putative lipoprotein YP_001477134.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001477135.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: yen:YE0909 putative dehydratase YP_001477136.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001477137.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001477138.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001477139.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE0914 putative LysR-family transcriptional regulatory protein YP_001477140.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_00223 putative drug efflux protein YP_001477141.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sgl:SG0587 hypothetical protein YP_001477142.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001477143.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_1052 metallo-beta-lactamase family protein YP_001477144.1 PFAM: Methyltransferase type 11; KEGG: yen:YE0920 hypothetical protein YP_001477145.1 PFAM: ribonuclease H; KEGG: ypi:YpsIP31758_1054 RNase H YP_001477146.1 3'-5' exonuclease of DNA polymerase III YP_001477147.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: kpn:KPN_01790 putative allantoin permease YP_001477148.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: kpn:KPN_01789 hypothetical transcriptional regulator YP_001477149.1 PFAM: Asp/Glu racemase; KEGG: kpn:KPN_01788 putative hydantoin racemase YP_001477150.1 PFAM: polysaccharide deacetylase; KEGG: ypi:YpsIP31758_1058 polysaccharide deacetylase family protein YP_001477151.1 KEGG: nmu:Nmul_D2814 transcriptional regulator, XRE family YP_001477152.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypi:YpsIP31758_0710 TonB-dependent siderophore receptor YP_001477153.1 KEGG: ypi:YpsIP31758_0711 aerobactin siderophore biosynthesis protein IucD YP_001477154.1 PFAM: IucA/IucC family protein; KEGG: ypp:YPDSF_0526 siderophore biosynthesis protein IucC YP_001477155.1 KEGG: ypi:YpsIP31758_0713 aerobactin siderophore biosynthesis protein IucB YP_001477156.1 PFAM: IucA/IucC family protein; KEGG: ypi:YpsIP31758_0714 aerobactin siderophore biosynthesis protein IucA YP_001477157.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_0530 membrane protein YP_001477158.1 PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: eca:ECA0065 hypothetical protein YP_001477159.1 PFAM: plasmid stabilization system; KEGG: plu:plu2306 hypothetical protein YP_001477160.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: plu:plu2305 hypothetical protein YP_001477161.1 KEGG: ypi:YpsIP31758_3195 hypothetical protein YP_001477162.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001477163.1 KEGG: ypi:YpsIP31758_3193 hypothetical protein YP_001477164.1 PFAM: gamma-glutamyltranspeptidase; KEGG: eca:ECA3497 putative gamma-glutamyltranspeptidase YP_001477165.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: eca:ECA3496 putative transcriptional regulator YP_001477166.1 PFAM: extracellular solute-binding protein family 3; KEGG: ypi:YpsIP31758_3190 amino acid ABC transporter, periplasmic amino acid-binding protein YP_001477167.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA3494 putative amino acid ABC transporter, permease protein YP_001477168.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3188 amino acid ABC transporter, permease protein YP_001477169.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3492 putative amino acid ABC transporter, ATP-binding protein YP_001477170.1 PFAM: aminotransferase class V; KEGG: eca:ECA3491 purine catabolism protein YP_001477171.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001477172.1 KEGG: nca:Noca_1144 putative urate oxidase, N-terminal YP_001477173.1 PFAM: Transthyretin; KEGG: sen:SACE_6735 transthyretin YP_001477174.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ypi:YpsIP31758_3184 hydrolase, carbon-nitrogen family YP_001477175.1 catalyzes the transfer of an amino moiety YP_001477176.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_001477177.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: eca:ECA3486 enolase-phosphatase YP_001477178.1 PFAM: Acireductone dioxygenase ARD; KEGG: yen:YE3231 dioxygenase YP_001477179.1 KEGG: eca:ECA3477 methylthioribose-1-phosphate isomerase; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_001477180.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_001477181.1 PFAM: Hok/gef cell toxic protein; KEGG: sty:HCM1.290c putative stable plasmid inheritance protein YP_001477182.1 PFAM: Hok/gef cell toxic protein; KEGG: sty:HCM1.290c putative stable plasmid inheritance protein YP_001477183.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001477184.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001477185.1 PFAM: glutamine amidotransferase class-II; KEGG: yps:YPTB0885 hypothetical protein YP_001477186.1 PFAM: protein of unknown function DUF949; KEGG: ypi:YpsIP31758_3169 hypothetical protein YP_001477187.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001477188.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001477189.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001477190.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001477191.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001477192.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001477193.1 PFAM: ApbE family lipoprotein; KEGG: yen:YE3214 thiamine biosynthesis lipoprotein YP_001477194.1 PFAM: protein of unknown function DUF539; KEGG: yen:YE3213 hypothetical protein YP_001477195.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: kpn:KPN_00246 hypothetical protein YP_001477196.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001477197.1 KEGG: yen:YE3206 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001477198.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001477199.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001477200.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001477201.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001477202.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001477203.1 PFAM: GCN5-related N-acetyltransferase; KEGG: stm:STM3653 putative acetyltransferase YP_001477205.1 KEGG: eca:ECA3962 hypothetical protein YP_001477206.1 PFAM: cytochrome B561; KEGG: eca:ECA0823 cytochrome B561 YP_001477207.1 PFAM: extracellular solute-binding protein family 5; KEGG: kpn:KPN_01918 dipeptide transport protein YP_001477208.1 PFAM: condensation domain protein; KEGG: bme:BMEII0076 enterobactin synthetase component F YP_001477209.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: vvy:VVA1309 ferric vulnibactin outer membrane receptor YP_001477210.1 PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: vvu:VV2_0830 non-ribosomal peptide synthetase modules YP_001477211.1 KEGG: kpn:KPN_01908 putative receptor YP_001477212.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: ent:Ent638_2072 flavin reductase domain protein, FMN-binding YP_001477215.1 PFAM: DSBA oxidoreductase; KEGG: sgl:SG2236 thiol:disulfide interchange protein YP_001477216.1 activator of genes involved in phenylacetic acid catabolism YP_001477217.1 PFAM: aldehyde dehydrogenase; KEGG: kpn:KPN_01455 phenylacetaldehyde dehydrogenase YP_001477218.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: aha:AHA_0057 lysine exporter protein YP_001477219.1 with TehA confers resistance to tellurite YP_001477220.1 PFAM: protein of unknown function DUF1615; KEGG: eca:ECA0433 putative lipoprotein YP_001477221.1 PFAM: Glutathione S-transferase domain; KEGG: bxe:Bxe_A4031 putative glutathione S-transferase YP_001477222.1 PFAM: alpha/beta hydrolase fold; KEGG: sen:SACE_1904 alpha/beta hydrolase YP_001477223.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rsq:Rsph17025_3347 hypothetical protein YP_001477224.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bxe:Bxe_B0109 putative pyruvate decarboxylase YP_001477225.1 catalyzes the transfer of palmitate to lipid A YP_001477226.1 KEGG: yen:YE0521 hypothetical protein YP_001477227.1 PFAM: protein of unknown function DUF333; KEGG: sfx:S1546 hypothetical protein YP_001477228.1 KEGG: psb:Psyr_4917 heat shock protein DnaJ, N-terminal YP_001477229.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: rsp:RSP_3064 transcriptional regulator, DeoR family YP_001477230.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ent:Ent638_0487 glyoxalase/bleomycin resistance protein/dioxygenase YP_001477231.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: reh:H16_B1922 transcriptional regulator, LysR-family YP_001477232.1 PFAM: Pirin domain protein; KEGG: bte:BTH_I1747 pirin family protein YP_001477233.1 PFAM: isochorismatase hydrolase; KEGG: pfl:PFL_4072 hydrolase, isochorismatase family YP_001477234.1 KEGG: kpn:KPN_02155 hypothetical protein YP_001477235.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: pfl:PFL_2261 protein of unknown function, DUF393 family YP_001477236.1 KEGG: ypi:YpsIP31758_3147 hypothetical protein YP_001477237.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pfl:PFL_3320 acetyltransferase, GNAT family YP_001477238.1 KEGG: pap:PSPA7_1156 hypothetical protein YP_001477239.1 SMART: helix-turn-helix domain protein; KEGG: eca:ECA3469 putative DNA-binding protein YP_001477240.1 PFAM: UbiE/COQ5 methyltransferase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: yen:YE3193 hypothetical protein YP_001477241.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001477242.1 KEGG: eca:ECA0924 hypothetical protein YP_001477243.1 PFAM: low temperature requirement A; KEGG: oan:Oant_2126 low temperature requirement A YP_001477244.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE3192 hypothetical protein YP_001477245.1 KEGG: ypp:YPDSF_2845 methyltransferase YP_001477246.1 PFAM: GCN5-related N-acetyltransferase; KEGG: oan:Oant_1313 GCN5-related N-acetyltransferase YP_001477247.1 PFAM: periplasmic binding protein; KEGG: yen:YE3190 hypothetical protein YP_001477248.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yen:YE3189 putative hydroxamate-type ferrisiderophore receptor YP_001477249.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pap:PSPA7_2969 probable acetyltransferase YP_001477250.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001477251.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bur:Bcep18194_B1773 transcriptional regulator, AraC family YP_001477252.1 KEGG: cvi:CV_3714 hypothetical protein YP_001477253.1 KEGG: kpn:KPN_00333 hypothetical protein YP_001477254.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: bja:bll3245 transcriptional regulatory protein YP_001477255.1 PFAM: Oligopeptide transporter OPT superfamily protein; KEGG: vei:Veis_1103 oligopeptide transporter OPT superfamily protein YP_001477256.1 PFAM: protein of unknown function DUF1177; KEGG: vei:Veis_1102 protein of unknown function DUF1177 YP_001477257.1 PFAM: AroM family protein; KEGG: ssn:SSON_0366 protein of aro operon, regulated by AroR YP_001477258.1 PFAM: protein of unknown function DUF1255; KEGG: ypi:YpsIP31758_3142 hypothetical protein YP_001477259.1 Required for efficient pilin antigenic variation YP_001477260.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: ypi:YpsIP31758_4031 sensory box histidine kinase/response regulator YP_001477261.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_0289 ABC transporter related YP_001477262.1 PFAM: inner-membrane translocator; KEGG: kpn:KPN_04488 putative carbohydrate ABC transport system permease YP_001477263.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_04487 D-ribose periplasmic binding protein YP_001477264.1 PFAM: protein of unknown function DUF1498; KEGG: yps:YPTB3804 hypothetical protein YP_001477265.1 KEGG: ypi:YpsIP31758_4026 putative fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II YP_001477266.1 PFAM: PfkB domain protein; KEGG: yps:YPTB3802 PfkB family carbohydrate kinase YP_001477267.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ent:Ent638_0283 two component transcriptional regulator, winged helix family YP_001477268.1 PFAM: ROK family protein; KEGG: kpn:KPN_00337 possible NAGC-like transcriptional regulator YP_001477269.1 KEGG: ypi:YpsIP31758_3738 prevent-host-death family protein YP_001477270.1 PFAM: PilT protein domain protein; KEGG: nmc:NMC1584 hypothetical protein YP_001477271.1 TIGRFAM: exonuclease SbcC; PFAM: SMC domain protein; KEGG: ypp:YPDSF_2840 hypothetical protein YP_001477272.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001477273.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_3136 phosphate regulon transcriptional regulatory protein PhoB YP_001477274.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001477275.1 TIGRFAM: phosphate binding protein; KEGG: eca:ECA1112 putative phosphate binding protein YP_001477276.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001477277.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: yen:YE3179 branched-chain amino acid transport system II carrier protein YP_001477278.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001477280.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ypi:YpsIP31758_1534 transporter, small conductance mechanosensitive ion channel (MscS) family YP_001477281.1 PFAM: glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: yen:YE3177 putative maltodextrin glucosidase YP_001477282.1 PFAM: regulatory protein LuxR; KEGG: gme:Gmet_2158 two component transcriptional regulator, LuxR family YP_001477283.1 PFAM: Fimbrial protein; KEGG: shm:Shewmr7_3393 fimbrial protein YP_001477284.1 PFAM: Fimbrial protein; KEGG: ent:Ent638_1072 fimbrial protein YP_001477285.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: kpn:KPN_00277 putative fimbrial usher YP_001477286.1 PFAM: pili assembly chaperone; KEGG: sec:SC0176 putative fimbrial chaparone YP_001477287.1 PFAM: Fimbrial protein; KEGG: shm:Shewmr7_3393 fimbrial protein YP_001477288.1 PFAM: integrase family protein; KEGG: ecv:APECO1_1681 hypothetical protein YP_001477289.1 KEGG: yen:YE3175 gamma-glutamyltranspeptidase precursor; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001477290.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ypi:YpsIP31758_3126 antioxidant, AhpC/TSA family YP_001477291.1 PFAM: protein of unknown function DUF479; KEGG: yen:YE3173 hypothetical protein YP_001477292.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001477293.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001477294.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001477295.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001477296.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001477297.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: stm:STM1387 response regulator YP_001477298.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: yen:YE1614 tetrathionate reductase complex: sensory transduction histidine kinase YP_001477299.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yen:YE1615 tetrathionate reductase subunit B YP_001477300.1 PFAM: Polysulphide reductase NrfD; KEGG: yen:YE1616 tetrathionate reductase subunit C YP_001477301.1 PFAM: molydopterin dinucleotide-binding region; KEGG: yen:YE1617 tetrathionate reductase subunit A YP_001477302.1 KEGG: eca:ECA1124 putative lipoprotein YP_001477303.1 PFAM: ATP-cone domain protein; KEGG: ypi:YpsIP31758_3118 transcriptional regulator, NrdR family YP_001477304.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001477305.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001477306.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001477307.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001477308.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001477309.1 PFAM: aldo/keto reductase; KEGG: ecp:ECP_0478 putative oxidoreductase YP_001477310.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001477311.1 PFAM: Polyprenyl synthetase; KEGG: yen:YE3154 geranyltranstransferase YP_001477312.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001477313.1 Required for the synthesis of the thiazole moiety YP_001477314.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA1135 4-methyl-5b-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_001477315.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001477316.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001477317.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE3146 putative transporter YP_001477318.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001477319.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: ypi:YpsIP31758_3101 cytochrome o ubiquinol oxidase, subunit IV YP_001477320.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: yen:YE3143 cytochrome o ubiquinol oxidase subunit III YP_001477321.1 KEGG: yen:YE3142 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: Cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome c oxidase subunit I YP_001477322.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: yen:YE3141 cytochrome o ubiquinol oxidase subunit II YP_001477323.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001477324.1 PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein YP_001477325.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001477326.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001477327.1 KEGG: yen:YE3134 ATP-dependent Clp protease proteolytic subunit ClpP; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14 ClpP YP_001477328.1 binds and unfolds substrates as part of the ClpXP protease YP_001477329.1 KEGG: yen:YE3132 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001477330.1 PFAM: histone family protein DNA-binding protein; KEGG: sdy:SDY_0292 DNA-binding protein HU-beta YP_001477331.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: yen:YE3130 peptidyl-prolyl cis-trans isomerase D YP_001477332.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eca:ECA1153 hypothetical protein YP_001477333.1 PFAM: thioesterase superfamily protein; KEGG: ent:Ent638_0910 thioesterase superfamily protein YP_001477334.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001477335.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE3126 hypothetical protein YP_001477336.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: yen:YE3125 putative haloacid dehalogenase-like hydrolase YP_001477337.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: yen:YE3124 putative pyridoxal-phosphate dependent protein YP_001477338.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: yen:YE3123 probable AsnC-family regulatory protein YP_001477339.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3122 probable ABC transporter (ATP-binding protein) YP_001477340.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3121 probable ATP transporter (ATP-binding protein) YP_001477341.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001477342.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: yen:YE3119 probable ammonium transporter YP_001477343.1 KEGG: yps:YPTB0975 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001477344.1 KEGG: yen:YE3117 putative lipoprotein YP_001477345.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: yen:YE3116 putative 6-O-methylguanine DNA methyltransferase family protein YP_001477346.1 PFAM: beta-lactamase domain protein; KEGG: stt:t1012 putative hydrolase YP_001477347.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: kpn:KPN_02555 putative xanthine/uracil/vitamin C permease YP_001477348.1 PFAM: amidohydrolase; KEGG: kpn:KPN_02554 putative amidohydrolase YP_001477349.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02553 putative transcriptional regulator (LysR family) YP_001477350.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001477351.1 KEGG: yen:YE3114 hypothetical protein YP_001477352.1 KEGG: yps:YPTB0980 hypothetical protein YP_001477353.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3111 ABC transport system ATP-binding protein YP_001477354.1 PFAM: ABC-3 protein; KEGG: yen:YE3110 putative ABC-transporter membrane protein YP_001477355.1 PFAM: periplasmic solute binding protein; KEGG: yen:YE3109 periplasmic solute binding protein YP_001477356.1 PFAM: ribosomal protein L36; KEGG: stm:STM0470 putative 50S ribosomal protein L36 (second copy) YP_001477357.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001477358.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE3101 multidrug efflux protein YP_001477359.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: yen:YE3100 multidrug efflux protein YP_001477360.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001477361.1 PFAM: DsrE family protein; KEGG: ypi:YpsIP31758_3065 DsrE family protein YP_001477362.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001477363.1 KEGG: yen:YE3096 hypothetical protein YP_001477364.1 PFAM: Primosomal replication priB and priC; KEGG: ypi:YpsIP31758_3062 primosomal replication protein N'' YP_001477365.1 PFAM: protein of unknown function DUF454; KEGG: yps:YPTB0990 hypothetical protein YP_001477366.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001477367.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001477368.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3058 conserved hypothetical protein TIGR00103 YP_001477369.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001477370.1 molecular chaperone YP_001477371.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001477372.1 PFAM: sugar diacid recognition domain protein; KEGG: sec:SC2489 putative regulatory protein YP_001477373.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: sec:SC2488 putative permease YP_001477374.1 PFAM: glycerate kinase; KEGG: ypi:YpsIP31758_4052 glycerate kinase YP_001477375.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001477376.1 PFAM: PfkB domain protein; KEGG: yen:YE3069 inosine-guanosine kinase YP_001477377.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001477378.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypn:YPN_0996 membrane efflux protein YP_001477379.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001477380.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: yen:YE3063 hypothetical protein YP_001477381.1 PFAM: GumN family protein; KEGG: eca:ECA1192 hypothetical protein YP_001477382.1 PFAM: Heavy metal transport/detoxification protein; KEGG: yen:YE3061 putative cation-transporting ATPase YP_001477383.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: yen:YE3060 putative regulatory protein YP_001477384.1 PFAM: protein of unknown function DUF107; KEGG: yen:YE3059 hypothetical protein YP_001477385.1 PFAM: band 7 protein; KEGG: yen:YE3058 hypothetical protein YP_001477386.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001477387.1 PFAM: Thioredoxin domain; KEGG: yen:YE3057 putative thioredoxin YP_001477388.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: yen:YE3056 probable short-chain dehydrogenase YP_001477389.1 PFAM: lipolytic protein G-D-S-L family; KEGG: ypi:YpsIP31758_3021 GDSL-like lipase/acylhydrolase family protein YP_001477390.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_2717 ABC transporter ATP-binding protein YP_001477391.1 PFAM: protein of unknown function DUF214; KEGG: yen:YE3053 putative permease YP_001477392.1 KEGG: ent:Ent638_3347 sugar transporter; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001477393.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) YP_001477394.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001477395.1 KEGG: ypi:YpsIP31758_3017 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001477396.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001477397.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ent:Ent638_0979 peptidylprolyl isomerase YP_001477398.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001477399.1 KEGG: yen:YE3046 hypothetical protein YP_001477400.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001477402.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ret:RHE_PD00126 probable aryl-alcohol dehydrogenase protein YP_001477403.1 KEGG: nfa:nfa43510 hypothetical protein YP_001477404.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pfo:Pfl_2479 NADH:flavin oxidoreductase/NADH oxidase YP_001477405.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bur:Bcep18194_B1199 zinc-containing alcohol dehydrogenase superfamily YP_001477406.1 PFAM: DSBA oxidoreductase; KEGG: bur:Bcep18194_B1200 DsbA oxidoreductase YP_001477407.1 KEGG: bur:Bcep18194_B1201 hypothetical protein YP_001477408.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bur:Bcep18194_B1198 transcriptional regulator, AraC family YP_001477409.1 KEGG: ent:Ent638_3518 beta-lactamase domain protein YP_001477410.1 PFAM: aldo/keto reductase; KEGG: msm:MSMEG_1304 rhizopine catabolism protein YP_001477411.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mlo:mll1582 probable transcriptional regulator YP_001477412.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: eca:ECA3603 putative flavodoxin YP_001477413.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE1 domain protein; KEGG: pen:PSEEN2260 diguanylate cyclase (GGDEF) domain YP_001477414.1 PFAM: Cold-shock protein DNA-binding; KEGG: yps:YPTB1087 hypothetical protein YP_001477415.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cvi:CV_3594 hypothetical protein YP_001477416.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2153 ABC transporter, ATP-binding protein YP_001477417.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2154 putative ABC transporter, permease YP_001477418.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2155 putative acetyltransferase YP_001477419.1 KEGG: ent:Ent638_2090 hypothetical protein YP_001477420.1 KEGG: eca:ECA2160 putative peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001477421.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001477422.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bld:BLi04103 putative bicyclomycin resistance protein YP_001477423.1 PFAM: regulatory protein TetR; KEGG: ecs:ECs1862 putative transcription regulatory protein YP_001477424.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: ypi:YpsIP31758_2957 CrcB protein YP_001477425.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein; KEGG: yen:YE3010 putative diguanylate cyclase/phosphodiesterase domain 1 protein YP_001477426.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001477427.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001477428.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001477429.1 PFAM: protein of unknown function DUF493; KEGG: sgl:SG0794 hypothetical protein YP_001477430.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001477431.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: yen:YE3004 rare lipoprotein A precursor YP_001477432.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: yen:YE3003 rod shape-determining protein YP_001477433.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: yen:YE3002 penicillin-binding protein 2 YP_001477434.1 PFAM: protein of unknown function DUF163; KEGG: ypi:YpsIP31758_2948 conserved hypothetical protein TIGR00246 YP_001477435.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: stm:STM0642 hypothetical protein YP_001477436.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001477437.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001477438.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001477439.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001477440.1 PFAM: protein of unknown function DUF1451; KEGG: yen:YE2995 hypothetical protein YP_001477441.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: sec:SC1637 acyl carrier protein phosphodiesterase YP_001477442.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001477443.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2994 putative glutamate/aspartate transport ATP-binding protein YP_001477444.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1312 glutamate/aspartate transport system permease protein YP_001477445.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2992 putative glutamate/aspartate transport system permease YP_001477446.1 PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE2991 putative amino acid-binding protein precursor YP_001477447.1 Transfers the fatty acyl group on membrane lipoproteins YP_001477448.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: yen:YE2988 hypothetical protein YP_001477449.1 PFAM: protein of unknown function UPF0054; KEGG: sec:SC0696 putative metal-dependent hydrolase YP_001477450.1 PFAM: PhoH family protein; KEGG: ypi:YpsIP31758_2916 PhoH family protein YP_001477451.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: stm:STM4289 putative alkylphosphonate uptake protein in phosphonate metabolism YP_001477452.1 KEGG: yen:YE2985 putative tRNA-thiotransferase; TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB YP_001477453.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001477454.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001477455.1 PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; Fibronectin type III domain protein; KEGG: pfl:PFL_2091 chitinase YP_001477456.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE2982 putative N-acetylglucosamine metabolism protein YP_001477457.1 PFAM: ROK family protein; KEGG: yen:YE2981 putative N-acetylglucosamine regulatory protein YP_001477458.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001477459.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001477460.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001477461.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001477462.1 PFAM: outer membrane porin; KEGG: ecv:APECO1_1383 hypothetical protein YP_001477463.1 KEGG: yen:YE2975 putative lipoprotein YP_001477464.1 PFAM: Carbohydrate-binding chitobiase/hexosaminidase-type domain protein; glycoside hydrolase family 20 domain protein; Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, catalytic core; KEGG: yen:YE2974 chitobiase precursor YP_001477465.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE0648 sugar efflux transporter YP_001477466.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) YP_001477468.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001477469.1 TIGRFAM: flavodoxin; PFAM: flavodoxin/nitric oxide synthase; KEGG: yen:YE2972 flavodoxin 1 YP_001477470.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: ypi:YpsIP31758_2899 transcriptional regulator, CopG family YP_001477471.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: yen:YE2969 hypothetical protein YP_001477472.1 negative modulator of the initiation of chromosome replication YP_001477473.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001477474.1 PFAM: transcriptional regulator PadR family protein; KEGG: ypi:YpsIP31758_0905 transcriptional regulator, PadR family YP_001477475.1 KEGG: yen:YE1258 hypothetical protein YP_001477476.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001477477.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001477478.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001477479.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001477480.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001477481.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001477482.1 KEGG: eca:ECA1344 hypothetical protein YP_001477483.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: eca:ECA1348 hypothetical protein YP_001477484.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001477485.1 PFAM: cyclic-AMP phosphodiesterase class-II; KEGG: yen:YE2956 putative 3',5'-cyclic-nucleotide phosphodiesterase YP_001477486.1 PFAM: protein of unknown function DUF34; KEGG: eca:ECA1350 hypothetical protein YP_001477487.1 PFAM: Allophanate hydrolase subunit 1; KEGG: yen:YE2955A hypothetical protein YP_001477488.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: yps:YPTB2909 hypothetical protein YP_001477489.1 PFAM: LamB/YcsF family protein; KEGG: yen:YE2953 hypothetical protein YP_001477490.1 PFAM: protein of unknown function DUF969; KEGG: ypi:YpsIP31758_1118 hypothetical protein YP_001477491.1 PFAM: protein of unknown function DUF979; KEGG: ypi:YpsIP31758_1119 hypothetical protein YP_001477492.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_001477493.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001477494.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001477495.1 TIGRFAM: Succinate dehydrogenase cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: yps:YPTB1143 succinate dehydrogenase cytochrome b-556 subunit YP_001477496.1 TIGRFAM: Succinate dehydrogenase hydrophobic membrane anchor; KEGG: yen:YE2947 succinate dehydrogenase hydrophobic membrane anchor protein YP_001477497.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001477498.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001477499.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001477500.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001477501.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001477502.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: ent:Ent638_1229 succinyl-CoA synthetase, alpha subunit YP_001477503.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: eca:ECA1365 cytochrome D ubiquinol oxidase subunit I YP_001477504.1 KEGG: yen:YE2938 cytochrome d ubiquinol oxidase subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001477505.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sdy:SDY_0682 putative outer membrane lipoprotein YP_001477506.1 TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: eca:ECA1368 hypothetical protein YP_001477507.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001477508.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001477509.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001477510.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001477511.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001477512.1 TIGRFAM: Peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: yen:YE2931 peptidoglycan-associated lipoprotein Pal YP_001477513.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001477514.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001477515.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: yen:YE2927 intergral membrane NMN transport protein PnuC YP_001477516.1 involved in zinc efflux across the cytoplasmic membrane YP_001477517.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: extracellular solute-binding protein family 3; KEGG: pfo:Pfl_1864 Hpt sensor hybrid histidine kinase YP_001477518.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: pfl:PFL_2955 DNA-binding response regulator, LuxR family YP_001477519.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001477520.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001477521.1 PFAM: PsiF repeat protein; KEGG: yen:YE2921 putative starvation-inducible protein YP_001477522.1 KEGG: yps:YPTB1168 aldose 1-epimerase (mutarotase); TIGRFAM: galactose mutarotase; PFAM: Aldose 1-epimerase YP_001477523.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001477524.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001477525.1 PFAM: Abortive infection protein; KEGG: ypi:YpsIP31758_2854 CAAX amino terminal protease family protein YP_001477526.1 PFAM: isochorismatase hydrolase; KEGG: aha:AHA_3239 isochorismatase family protein YP_001477527.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001477528.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001477529.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: mms:mma_0066 TonB-dependent receptor YP_001477530.1 PFAM: periplasmic binding protein; KEGG: msm:MSMEG_4561 ABC Fe3+-siderophores transporter, periplasmic binding protein YP_001477531.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pau:PA14_39660 hypothetical protein YP_001477532.1 PFAM: transport system permease protein; KEGG: msm:MSMEG_4559 ABC transporter, membrane spanning protein YP_001477533.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cmi:CMM_0365 putative Fe3+-siderophore ABC transporter, ATPase component YP_001477534.1 KEGG: ypi:YpsIP31758_2851 hypothetical protein YP_001477535.1 with ModCB is involved in the high-affinity transport of molybdate YP_001477536.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001477537.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001477538.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001477539.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001477540.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001477541.1 PFAM: protein of unknown function DUF1232; KEGG: gme:Gmet_2189 protein of unknown function DUF1232 YP_001477542.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001477543.1 KEGG: eca:ECA2825 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001477544.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001477545.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: ypi:YpsIP31758_2842 biotin biosynthesis protein BioC YP_001477546.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001477548.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2903 putative amino acid transporter YP_001477549.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001477550.1 KEGG: ypi:YpsIP31758_2838 hypothetical protein YP_001477551.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: ypi:YpsIP31758_2837 hypothetical protein YP_001477552.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001477553.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: kpn:KPN_00811 molybdopterin biosynthesis protein B YP_001477554.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001477555.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001477556.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001477557.1 PFAM: protein of unknown function UPF0005; KEGG: eca:ECA2812 putative membrane protein YP_001477558.1 PFAM: ABC-2 type transporter; KEGG: ypi:YpsIP31758_2815 ABC transporter, permease protein YP_001477559.1 PFAM: ABC-2 type transporter; KEGG: yen:YE2893 hypothetical protein YP_001477560.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2813 ABC transporter, ATP-binding protein YP_001477561.1 PFAM: secretion protein HlyD family protein; KEGG: yen:YE2891 HlyD family secretion protein YP_001477562.1 PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: ypi:YpsIP31758_2811 transcriptional regulator, TetR family YP_001477563.1 this helicase is not essential cell growth YP_001477564.1 PFAM: secretion protein HlyD family protein; KEGG: ppu:PP_1272 multidrug efflux MFS membrane fusion protein, putative YP_001477565.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl_0142 major facilitator superfamily MFS_1 YP_001477566.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ftn:FTN_0720 transcriptional regulator, IclR family YP_001477567.1 PFAM: UspA domain protein; KEGG: pen:PSEEN4556 universal stress protein family YP_001477568.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sco:SCO2696 2-hydroxyacid-family dehydrogenase YP_001477569.1 PFAM: dihydrouridine synthase DuS; KEGG: ypi:YpsIP31758_2808 tRNA-dihydrouridine synthase YP_001477570.1 PFAM: N-acetyltransferase; KEGG: mxa:MXAN_1194 N-acetyltransferase family protein YP_001477571.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_B0248 transcriptional regulator, LysR family YP_001477572.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pfl:PFL_0285 hypothetical protein YP_001477573.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02452 putative bacterial regulatory protein, LysR YP_001477575.1 PFAM: polysaccharide biosynthesis protein; KEGG: afw:Anae109_1236 polysaccharide biosynthesis protein YP_001477576.1 KEGG: bca:BCE_5388 hypothetical protein YP_001477577.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pin:Ping_2316 transcriptional regulator, substrate-binding of LysR family protein YP_001477578.1 KEGG: yen:YE2064 hypothetical protein YP_001477579.1 PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2147 L-asparagine permease YP_001477580.1 PFAM: transmembrane pair domain protein; KEGG: pau:PA14_28430 hypothetical protein YP_001477581.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pap:PSPA7_2479 probable transcriptional regulator YP_001477582.1 PFAM: SNARE associated Golgi protein; KEGG: sdy:SDY_2152 hypothetical protein YP_001477583.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; S-adenosyl-L-homocysteine hydrolase, NAD binding; KEGG: kpn:KPN_02462 putative S-adenosylhomocysteine hydrolase YP_001477584.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001477585.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: oan:Oant_1566 3-demethylubiquinone-9 3-methyltransferase YP_001477587.1 PFAM: protein of unknown function DUF808; KEGG: pap:PSPA7_3434 hypothetical protein YP_001477588.1 PFAM: GCN5-related N-acetyltransferase; KEGG: kpn:KPN_02570 hypothetical acetyltransferase YP_001477589.1 PFAM: regulatory protein MerR; Albicidin resistance; Transcription regulator MerR DNA binding; KEGG: kpn:KPN_02240 putative albicidin resistance protein YP_001477590.1 KEGG: ecs:ECs4710 hypothetical protein YP_001477591.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: eca:ECA1498 lipoprotein-28 precursor YP_001477592.1 PFAM: protein of unknown function DUF1460; KEGG: pfl:PFL_0370 lipoprotein, putative YP_001477593.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pfo:Pfl_2189 GCN5-related N-acetyltransferase YP_001477594.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: kpn:KPN_04414 UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase YP_001477595.1 PFAM: protein of unknown function DUF1282; KEGG: yen:YE2135 hypothetical protein YP_001477596.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001477597.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: kpn:KPN_01674 methionine aminopeptidase YP_001477598.1 KEGG: pen:PSEEN1416 hypothetical protein YP_001477599.1 KEGG: yen:YE3211 D-alanine--D-alanine ligase A; TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; D-alanine--D-alanine ligase domain protein YP_001477600.1 PFAM: extracellular solute-binding protein family 3; KEGG: bam:Bamb_0110 extracellular solute-binding protein, family 3 YP_001477601.1 catalyzes the transfer of an amino moiety YP_001477602.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_4813 transcriptional regulator, LysR family YP_001477603.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: eca:ECA2790 periplasmic beta-glucosidase YP_001477604.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3096 ABC-transporter periplasmic-binding component YP_001477605.1 PFAM: transport system permease protein; KEGG: eca:ECA3095 ABC transporter permease protein YP_001477606.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hin:HI1470 putative iron transport system ATP-binding protein YP_001477607.1 KEGG: kpn:KPN_02127 molybdate transport protein (ABC superfamily, peri_bind) YP_001477609.1 KEGG: ent:Ent638_4322 cobyrinic acid a,c-diamide synthase YP_001477610.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: yen:YE2881 hypothetical protein YP_001477611.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ngo:NGO1928 putative acetyltransferase YP_001477612.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_2438 transcriptional regulator, LysR family YP_001477613.1 PFAM: major facilitator superfamily MFS_1; KEGG: nfa:nfa29650 putative transporter YP_001477614.1 PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_3518 carbohydrate kinase, FGGY family YP_001477615.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE0523 hypothetical protein YP_001477616.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: pfo:Pfl_2164 lysine exporter protein (LysE/YggA) YP_001477617.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: psa:PST_2925 transcriptional regulator, AraC family YP_001477618.1 PFAM: protein of unknown function RIO1; KEGG: yen:YE1747 hypothetical protein YP_001477619.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001477620.1 PFAM: protein of unknown function DUF799; KEGG: eca:ECA4458 putative lipoprotein YP_001477621.1 KEGG: yen:YE1235 putative lipoprotein YP_001477622.1 PFAM: Curli production assembly/transport component CsgG; KEGG: eca:ECA4460 putative lipoprotein YP_001477623.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; KEGG: shn:Shewana3_3368 transcriptional regulator, MarR family with acetyltransferase activity YP_001477624.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE2851 hypothetical protein YP_001477625.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE2851 hypothetical protein YP_001477626.1 PFAM: regulatory protein TetR; KEGG: sgl:SG2094 putative transcriptional repressor YP_001477627.1 PFAM: NLPA lipoprotein; KEGG: ent:Ent638_1773 NlpA lipoprotein YP_001477628.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_1772 binding-protein-dependent transport systems inner membrane component YP_001477629.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_1771 ABC transporter related YP_001477630.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pap:PSPA7_3901 acetyltransferase, GNAT family YP_001477631.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bte:BTH_I0388 transcriptional regulator, LysR family YP_001477632.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bca:BCE_3496 quinone oxidoreductase YP_001477633.1 KEGG: ppf:Pput_4568 hypothetical protein YP_001477634.1 KEGG: ypi:YpsIP31758_2801 hypothetical protein YP_001477635.1 PFAM: isochorismatase hydrolase; KEGG: she:Shewmr4_1847 isochorismatase hydrolase YP_001477636.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pae:PA1827 probable short-chain dehydrogenase YP_001477637.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_B1001 transcriptional regulator, LysR family YP_001477638.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001477639.1 PFAM: major facilitator superfamily MFS_1; KEGG: ecj:JW4319 predicted transporter YP_001477640.1 PFAM: GntR domain protein; KEGG: ecj:JW5792 predicted DNA-binding transcriptional regulator YP_001477641.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ecs:ECs5318 putative oxidoreductase YP_001477642.1 KEGG: yen:YE2878 putative ABC transport ATP-binding subunit; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001477643.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: yen:YE2877 putative substrate-binding periplasmic transport protein YP_001477644.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2797 phosphonate ABC transporter, permease protein YP_001477645.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2796 phosphonate ABC transporter, permease protein YP_001477646.1 PFAM: protein of unknown function DUF1456; KEGG: yps:YPTB1227 hypothetical protein YP_001477647.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE2573 methyl-accepting chemotaxis protein YP_001477648.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: kpn:KPN_04684 putative sulfate transporter YP_001477649.1 PFAM: carbonic anhydrase; KEGG: kpn:KPN_04685 putative carbonic anhdrase YP_001477650.1 catalyzes the hydrolysis of allophanate YP_001477651.1 TIGRFAM: urea amidolyase related protein; Urea carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: pmy:Pmen_0703 UreA amidolyase related protein YP_001477652.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: eca:ECA2143 GntR-family transcriptional regulator YP_001477653.1 KEGG: ent:Ent638_1988 putative substrate-binding periplasmic transport protein YP_001477654.1 PFAM: inner-membrane translocator; KEGG: yen:YE2872 putative branched-chain amino acid transport system, permease component YP_001477655.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB1230 ABC type branched-chain amino acid transporter, permease protein YP_001477656.1 PFAM: ABC transporter related; KEGG: eca:ECA2147 putative ABC transport ATP-binding subunit YP_001477657.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA2148 putative ABC transport ATP-binding subunit YP_001477658.1 KEGG: xau:Xaut_3206 hypothetical protein YP_001477660.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pfl:PFL_2567 acetyltransferase, GNAT family, putative YP_001477661.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: nwi:Nwi_2327 hypothetical protein YP_001477662.1 KEGG: rle:RL4058 hypothetical protein YP_001477663.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rle:RL4055 putative LysR family transcriptional regulator YP_001477664.1 PFAM: Rhodanese domain protein; KEGG: yen:YE2868 putative sulfurtransferase YP_001477665.1 KEGG: yen:YE2059 putative virulence factor YP_001477666.1 PFAM: virulence protein SrfB; KEGG: yen:YE2058 putative virulence factor YP_001477667.1 KEGG: eca:ECA2219 putative virulence effector protein YP_001477668.1 PFAM: NUDIX hydrolase; KEGG: ssa:SSA_0239 7,8-dihydro-8-oxoguanine-triphosphatase, putative YP_001477669.1 PFAM: protein of unknown function DUF523; KEGG: eca:ECA1770 hypothetical protein YP_001477671.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bld:BLi02818 hypothetical protein YP_001477672.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: pfo:Pfl_5531 aminotransferase, class I and II YP_001477673.1 KEGG: pfo:Pfl_5530 hypothetical protein YP_001477674.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yen:YE2867 hypothetical protein YP_001477675.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bxe:Bxe_C0113 major facilitator superfamily (MFS) transporter YP_001477676.1 PFAM: fatty acid desaturase; KEGG: yen:YE2866 putative fatty acid desaturase YP_001477677.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: yen:YE2865 putative substrate-binding transport protein YP_001477678.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2785 quaternary amine uptake ABC transporter (QAT) family, permease protein YP_001477679.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1238 ABC type choline/glycine/betaine transporter, ATP-binding subunit YP_001477680.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2783 quaternary amine uptake ABC transporter (QAT) family, permease protein YP_001477681.1 KEGG: yen:YE2861 hypothetical protein YP_001477682.1 KEGG: plu:plu1523 hypothetical protein YP_001477683.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_2779 integral membrane protein YP_001477684.1 KEGG: yen:YE4157 hypothetical protein YP_001477685.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE4158 putative transport protein YP_001477686.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: sco:SCO6802 DNA-binding protein YP_001477687.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_3493 probable acetyltransferase protein YP_001477688.1 TIGRFAM: 5'-nucleotidase, lipoprotein e(P4) family; PFAM: acid phosphatase (Class B); KEGG: oan:Oant_2497 5'-nucleotidase, lipoprotein E(P4) family YP_001477689.1 PFAM: GCN5-related N-acetyltransferase; KEGG: kpn:KPN_04800 putative N-acetyltransferase YP_001477690.1 PFAM: porin Gram-negative type; KEGG: yen:YE2856 outer membrane protein C2 YP_001477691.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: rfr:Rfer_2441 carboxymuconolactone decarboxylase YP_001477692.1 KEGG: cvi:CV_3287 probable tautomerase YP_001477693.1 helicase involved in DNA repair and perhaps also replication YP_001477694.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: kpn:KPN_02209 putative regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system YP_001477695.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ret:RHE_CH00327 putative transporter permease protein YP_001477696.1 SMART: helix-turn-helix domain protein; KEGG: rpa:RPA1926 possible transcriptional regulator, XRE family YP_001477697.1 PFAM: major facilitator superfamily MFS_1; KEGG: rpa:RPA1925 putative transmembrane protein YP_001477698.1 PFAM: Negative transcriptional regulator; KEGG: mlo:mll0013 transcriptional regulator YP_001477699.1 PFAM: glycosyl transferase family 3; KEGG: ypp:YPDSF_1932 glycosyl transferase YP_001477700.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: yen:YE2852 putative peptidase YP_001477701.1 KEGG: son:SO0492 hypothetical flavoprotein oxygenase YP_001477702.1 PFAM: protein of unknown function DUF890; KEGG: yen:YE2849 hypothetical protein YP_001477703.1 KEGG: jan:Jann_4218 allergen V5/TPX-1 related YP_001477704.1 KEGG: ypp:YPDSF_1927 chemotactic transducer; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001477705.1 PFAM: regulatory protein TetR; KEGG: aha:AHA_0553 transcriptional regulator, TetR family YP_001477706.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cbh:CLC_0910 acetyltransferase, GNAT family YP_001477707.1 KEGG: lwe:lwe1084 hydrolase family protein YP_001477708.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sec:SC0822 paral putative transport protein YP_001477709.1 similar to ATP-binding component of ABC transporters YP_001477710.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001477711.1 similar to periplasmic-binding component of ABC transporters YP_001477712.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: yen:YE2844 DksA/TraR C4-type zinc finger protein YP_001477713.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001477714.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_1296 hypothetical protein YP_001477715.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_1500 integral membrane protein YP_001477716.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001477717.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ent:Ent638_1888 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001477718.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2048 LysR-family transcriptional regulatory protein YP_001477719.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bxe:Bxe_B0244 putative acetyltransferase, GnaT family YP_001477720.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001477721.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: eca:ECA4330 putative isomerase YP_001477722.1 PFAM: class II aldolase/adducin family protein; KEGG: yen:YE2502 putative class II aldolase-family protein YP_001477723.1 PFAM: type III effector Hrp-dependent outers; KEGG: eca:ECA4328 hypothetical protein YP_001477724.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: eca:ECA4327 putative oxidoreductase YP_001477725.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: eca:ECA4325 DeoR-family trancriptional regulator YP_001477727.1 PFAM: oxidoreductase molybdopterin binding; KEGG: psb:Psyr_3371 oxidoreductase, molybdopterin binding YP_001477728.1 KEGG: psp:PSPPH_3292 HupC/HyaC/HydC family protein YP_001477729.1 KEGG: pau:PA14_64560 hypothetical protein YP_001477730.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pae:PA4885 two-component response regulator YP_001477731.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: psb:Psyr_3375 heavy metal sensor kinase YP_001477732.1 PFAM: transcriptional regulator domain protein; KEGG: ecp:ECP_4609 hypothetical protein YP_001477733.1 PFAM: regulatory protein LuxR; KEGG: reh:H16_B1626 response regulator, NarL-family YP_001477734.1 KEGG: ecs:ECs0323 hypothetical protein YP_001477735.1 KEGG: kpn:KPN_00292 hypothetical protein YP_001477736.1 KEGG: kpn:KPN_00293 putative enzyme YP_001477737.1 KEGG: kpn:KPN_00294 putative receptor YP_001477738.1 KEGG: kpn:KPN_00295 hypothetical protein YP_001477739.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_0544 periplasmic sensor signal transduction histidine kinase YP_001477740.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bur:Bcep18194_C6809 two component transcriptional regulator, winged helix family YP_001477741.1 KEGG: mms:mma_3541 thiosulfate reductase cytochrome b subunit (membrane anchoring protein) YP_001477742.1 PFAM: oxidoreductase molybdopterin binding; KEGG: pol:Bpro_2730 oxidoreductase, molybdopterin binding YP_001477743.1 TIGRFAM: Pentapeptide MXKDX repeat protein; KEGG: pol:Bpro_0540 hypothetical protein YP_001477744.1 proton-motive-force-driven choline transporter YP_001477745.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001477746.1 catalyzes the formation of betaine from betaine aldehyde YP_001477747.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001477748.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: pap:PSPA7_1539 hypothetical protein YP_001477750.1 PFAM: EAL domain protein; KEGG: kpn:KPN_03274 hypothetical protein YP_001477751.1 PFAM: Fimbrial protein; KEGG: bpd:BURPS668_2033 fimbrial protein YP_001477752.1 PFAM: pili assembly chaperone; KEGG: kpn:KPN_02985 probable pilin chaperone YP_001477753.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: kpn:KPN_02986 outer membrane protein; export and assembly of type 1 fimbriae YP_001477754.1 KEGG: pae:PA0498 hypothetical protein YP_001477755.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sgl:SG0402 right origin-binding protein YP_001477756.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001477757.1 PFAM: NmrA family protein; KEGG: stp:Strop_2997 NmrA family protein YP_001477758.1 PFAM: regulatory protein TetR; KEGG: oan:Oant_1673 transcriptional regulator, TetR family YP_001477759.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_237 hypothetical protein YP_001477760.1 PFAM: Alkaline phosphatase; KEGG: yen:YE2068 alkaline phosphatase precursor YP_001477761.1 PFAM: Glutathione S-transferase domain; KEGG: mlo:mlr4954 glutathione S-transferase YP_001477762.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: mlo:mll4602 hypothetical protein YP_001477763.1 KEGG: pfl:PFL_3428 hypothetical protein YP_001477764.1 KEGG: hch:HCH_03746 hypothetical protein YP_001477765.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001477766.1 PFAM: carbonic anhydrase; KEGG: bam:Bamb_5945 carbonate dehydratase YP_001477767.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001477771.1 KEGG: mes:Meso_3017 hypothetical protein YP_001477772.1 SMART: AAA ATPase; KEGG: ret:RHE_PE00189 hypothetical protein YP_001477773.1 PFAM: helix-turn-helix domain protein; KEGG: plu:plu4475 hypothetical protein YP_001477775.1 PFAM: Resolvase domain; KEGG: gox:GOX2728 truncated transposon gamma-delta resolvase YP_001477776.1 PFAM: Resolvase domain; Recombinase; KEGG: mms:mma_3169 site-specific recombinase YP_001477777.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA3010 ABC transporter ATP-binding protein YP_001477778.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001477779.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001477780.1 PFAM: protein of unknown function DUF924; KEGG: yen:YE2827 hypothetical protein YP_001477781.1 PFAM: peptidase T2 asparaginase 2; KEGG: eca:ECA0132 L-asparaginase YP_001477782.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: eca:ECA2835 putative ABC transporter ATP-binding protein YP_001477783.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2834 putative ABC transporter periplasmic binding protein YP_001477784.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2833 putative ABC transporter permease protein YP_001477785.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_1326 binding-protein-dependent transport systems inner membrane component YP_001477786.1 PFAM: Post-segregation antitoxin CcdA; KEGG: yen:YE3481 gyrase inhibitor antitoxin YP_001477787.1 PFAM: CcdB protein; KEGG: yen:YE3480 cytotoxic protein YP_001477788.1 KEGG: yen:YE2822 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001477789.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: yen:YE2821 probable alcohol dehydrogenase YP_001477790.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2820 putative LysR-family transcriptional regulatory protein YP_001477791.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: yen:YE2819 hypothetical protein YP_001477792.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001477793.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: yen:YE2817 hypothetical protein YP_001477794.1 negative regulator of the mglBAC operon for galactose utilization YP_001477795.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE2815 galactose-binding protein YP_001477796.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001477797.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001477798.1 PFAM: protein of unknown function DUF218; KEGG: yen:YE2795 hypothetical protein YP_001477799.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001477800.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001477801.1 PFAM: LrgB family protein; KEGG: yen:YE2791 hypothetical protein YP_001477802.1 PFAM: LrgA family protein; KEGG: yen:YE2790 hypothetical protein YP_001477803.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE2789 putative multidrug resistance protein YP_001477804.1 PFAM: protein of unknown function DUF559; KEGG: pla:Plav_1553 protein of unknown function DUF559 YP_001477805.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001477806.1 KEGG: yen:YE2784 hypothetical protein YP_001477807.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sgl:SG0972 hypothetical protein YP_001477808.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001477809.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001477810.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001477811.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_001477812.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: yen:YE2779 hypothetical protein YP_001477813.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: yen:YE2778 UTP-glucose-1-phosphate uridylyltransferase YP_001477814.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: yen:YE2777 UTP-glucose-1-phosphate uridylyltransferase YP_001477815.1 PFAM: polysaccharide export protein; KEGG: eca:ECA1417 putative polysaccharide export protein YP_001477816.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: kpn:KPN_02511 protein tyrosine phosphatase YP_001477817.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: kpn:KPN_02510 tyrosine autokinase YP_001477819.1 PFAM: glycosyl transferase group 1; KEGG: mba:Mbar_A0239 mannosyltransferase YP_001477820.1 PFAM: glycosyl transferase group 1; KEGG: cac:CAC3057 glycosyltransferase YP_001477822.1 PFAM: glycosyl transferase group 1; KEGG: bfr:BF3922 probable mannosyltransferase YP_001477823.1 PFAM: polysaccharide biosynthesis protein; KEGG: fjo:Fjoh_2240 polysaccharide biosynthesis protein YP_001477824.1 PFAM: glycosyl transferase group 1; KEGG: bha:BH3663 lipopolysaccharide biosynthesis YP_001477825.1 KEGG: pst:PSPTO_5546 hypothetical protein YP_001477826.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_001477827.1 KEGG: ava:Ava_4160 VCBS YP_001477828.1 KEGG: plu:plu0657 ATP-binding protein PrtB; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001477829.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: plu:plu0658 membrane fusion protein PrtC YP_001477830.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: plu:plu0659 outer membrane protein PrtD YP_001477831.1 KEGG: eca:ECA1438 mannose-1-phosphate guanylyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_001477832.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: ent:Ent638_2662 phosphomannomutase YP_001477833.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) YP_001477834.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: eca:ECA1416 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_001477835.1 PFAM: glycosyl transferase group 1; KEGG: sdy:SDY_PA04 RfpB YP_001477836.1 PFAM: glycosyl transferase group 1; KEGG: asa:ASA_1456 glycosyltransferase YP_001477838.1 PFAM: polysaccharide biosynthesis protein; KEGG: vfi:VF0170 flippase YP_001477840.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001477841.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001477842.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001477843.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001477844.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001477845.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001477846.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001477847.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001477848.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001477849.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: yen:YE2764 hypothetical protein YP_001477850.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pae:PA1145 probable transcriptional regulator YP_001477851.1 TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bmn:BMA10247_A0674 agmatinase YP_001477852.1 PFAM: Na+/solute symporter; KEGG: pae:PA1418 probable sodium:solute symport protein YP_001477853.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: reh:H16_A0087 putative Mg2+ and Co2+ transporter YP_001477854.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_01386 histone acetyltransferase HPA2/related acetyltransferase YP_001477855.1 PFAM: Glutathione S-transferase domain; KEGG: pfl:PFL_1771 glutathione S-transferase YP_001477856.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; KEGG: yen:YE1464 putative hydrolase YP_001477857.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: yen:YE1465 putative iron/ascorbate oxidoreductase family protein YP_001477858.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: yen:YE1469 putative cystathionine gamma-synthase YP_001477859.1 PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: yen:YE1470 cystathionine beta-lyase YP_001477860.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: yen:YE1471 D-alanyl-D-alanine carboxypeptidase YP_001477861.1 KEGG: yen:YE1472 L-serine dehydratase 2; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001477862.1 TIGRFAM: serine transporter; PFAM: aromatic amino acid permease; KEGG: yen:YE1473 serine transporter YP_001477863.1 PFAM: regulatory protein DeoR; KEGG: yen:YE1474 deoxyribose operon repressor YP_001477864.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001477865.1 KEGG: yen:YE2065 hypothetical protein YP_001477866.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: yen:YE1476 putative permease YP_001477867.1 KEGG: yen:YE1477 hypothetical protein YP_001477868.1 PFAM: purine or other phosphorylase family 1; KEGG: btl:BALH_2989 putative 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase YP_001477869.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001477870.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pfl:PFL_3440 serine/threonine dehydratase family protein YP_001477871.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: yen:YE1478 TrkA, potassium channel-family protein YP_001477872.1 KEGG: eca:ECA2682 hypothetical protein YP_001477873.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001477874.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001477875.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: stm:STM0875 ribosomal protein S6 modification protein YP_001477876.1 KEGG: ypi:YpsIP31758_2646 hypothetical protein YP_001477877.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_2645 putrescine ABC transporter, periplasmic putrescine binding protein YP_001477878.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001477879.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1486 putrescine transport system permease protein YP_001477880.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2642 putrescine ABC transporter, permease protein YP_001477881.1 KEGG: eca:ECA2673 hypothetical protein YP_001477882.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001477883.1 KEGG: psb:Psyr_3832 prevent-host-death protein YP_001477884.1 KEGG: ypi:YpsIP31758_2639 arginine ABC transporter, periplasmic substrate-binding protein ArtJ; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001477885.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001477886.1 with ArtPMJI transports arginine across the inner membrane YP_001477887.1 KEGG: yen:YE1495 arginine-binding periplasmic protein 1 precursor; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001477888.1 With ArtMQJI transports arginine across the inner membrane YP_001477889.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001477890.1 PFAM: protein of unknown function DUF74; KEGG: eca:ECA2666 hypothetical protein YP_001477891.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: eca:ECA2665 putative N-acetylmuramoyl-L-alanine amidase YP_001477892.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: yen:YE1503 hypothetical protein YP_001477893.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ypi:YpsIP31758_2621 NAD dependent epimerase/dehydratase family protein YP_001477894.1 PFAM: protein of unknown function DUF1294; KEGG: stm:STM1632 putative inner membrane protein YP_001477895.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001477896.1 catalyzes the formation of acetate from pyruvate YP_001477897.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: eca:ECA2663 NADH oxidoreductase YP_001477898.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001477899.1 PFAM: protein of unknown function DUF340 membrane; KEGG: yen:YE1511 hypothetical protein YP_001477900.1 KEGG: ypi:YpsIP31758_2614 hypothetical protein YP_001477901.1 PFAM: protein of unknown function DUF535; KEGG: yen:YE1513 putative virulence factor YP_001477902.1 confers macrolide resistance via active drug efflux YP_001477903.1 with MacA is involved in the export of macrolide YP_001477904.1 KEGG: stm:STM0943 similar to CspA but not cold shock induced; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_001477905.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001477906.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001477907.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001477908.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001477909.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001477910.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001477911.1 PFAM: Glutathione S-transferase domain; KEGG: pfo:Pfl_2442 glutathione S-transferase-like YP_001477912.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_4591 transcriptional regulator, LysR family YP_001477913.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: yen:YE1523 thioredoxin reductase YP_001477914.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001477915.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: yen:YE1525 putative cell division protein YP_001477916.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001477917.1 PFAM: magnesium chelatase ChlI subunit; AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: yen:YE1527 putative ATPase protein YP_001477918.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001477919.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: kpn:KPN_01580 putative dimethyl sulfoxide reductase, major subunit YP_001477920.1 TIGRFAM: Dimethylsulfoxide reductase chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: kpn:KPN_00927 anaerobic dimethyl sulfoxide (DMSO) reductase, subunit B YP_001477921.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: ypp:YPDSF_3037 anaerobic dimethyl sulfoxide reductase chain C YP_001477922.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001477923.1 KEGG: plu:plu2183 hypothetical protein YP_001477924.1 KEGG: plu:plu2184 hypothetical protein YP_001477925.1 KEGG: plu:plu2185 hypothetical protein YP_001477926.1 PFAM: NUDIX hydrolase; KEGG: ppr:PBPRB0736 hypothetical protein YP_001477927.1 PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein YP_001477928.1 KEGG: plu:plu2181 hypothetical protein YP_001477929.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: plu:plu2182 hypothetical protein YP_001477930.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; KEGG: plu:plu2186 hypothetical protein YP_001477931.1 PFAM: Indigoidine synthase A family protein; KEGG: plu:plu2187 hypothetical protein YP_001477932.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1530 hypothetical protein YP_001477933.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001477934.1 KEGG: yen:YE1532 formate acetyltransferase 1; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001477935.1 PFAM: formate/nitrite transporter; KEGG: yen:YE1533 putative formate transporter 1 YP_001477936.1 PFAM: protein of unknown function DUF181; KEGG: ypi:YpsIP31758_2587 hypothetical protein YP_001477937.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001477938.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001477939.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001477940.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001477941.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001477942.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001477943.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: yen:YE1542 hypothetical protein YP_001477944.1 involved in the transport of lipid A across the inner membrane YP_001477945.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001477946.1 PFAM: protein of unknown function DUF1338; KEGG: pen:PSEEN5405 hypothetical protein YP_001477947.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yen:YE1546 putative cold shock protein CspE2 YP_001477948.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypi:YpsIP31758_2574 cold shock DNA-binding domain protein YP_001477949.1 PFAM: protein of unknown function DUF1006; KEGG: cvi:CV_0245 hypothetical protein YP_001477950.1 PFAM: protein of unknown function DUF343; KEGG: ypi:YpsIP31758_2572 hypothetical protein YP_001477951.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001477952.1 KEGG: yen:YE1551 hypothetical protein YP_001477953.1 PFAM: protein of unknown function DUF218; KEGG: yen:YE1552 putative inner membrane protein YP_001477954.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001477955.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001477956.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001477957.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001477958.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: yen:YE1557 hypothetical protein YP_001477959.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: yen:YE1558 hypothetical protein YP_001477960.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2561 metallo-beta-lactamase family protein YP_001477961.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001477962.1 PFAM: porin Gram-negative type; KEGG: stm:STM1473 outer membrane protein N precursor YP_001477963.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001477964.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001477965.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sun:SUN_1205 signal transduction response regulator YP_001477966.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: yps:YPTB1438 putative aminopeptidase N YP_001477967.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001477968.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_0355 putative ABC aliphatic sulfonates transporter, permease subunit YP_001477969.1 catalyzes the release of sulfite from alkanesulfonates YP_001477970.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_001477971.1 PFAM: NADPH-dependent FMN reductase; KEGG: ypi:YpsIP31758_0352 NADPH-dependent FMN reductase YP_001477972.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001477973.1 PFAM: protein of unknown function DUF1379; KEGG: yen:YE1569 hypothetical protein YP_001477974.1 PFAM: ferredoxin; MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: yen:YE1570 putative iron-sulfur binding protein YP_001477975.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001477976.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001477977.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: yen:YE1573 putative paraquat-inducible protein A YP_001477978.1 PFAM: Mammalian cell entry related domain protein; KEGG: eca:ECA2532 paraquat-inducible protein B YP_001477979.1 PFAM: protein of unknown function DUF330; KEGG: yen:YE1575 putative lipoprotein protein YP_001477980.1 PFAM: ribosome modulation factor; KEGG: stm:STM1066 ribosome modulation factor (involved in dimerization of 70S ribosomes) YP_001477981.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001477982.1 PFAM: helix-turn-helix HxlR type; KEGG: yen:YE1577 hypothetical protein YP_001477983.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001477984.1 KEGG: yen:YE1579 putative Lon protease YP_001477985.1 PFAM: protein of unknown function DUF1047; KEGG: yen:YE1580 hypothetical protein YP_001477986.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001477987.1 PFAM: cell division inhibitor SulA; KEGG: yen:YE1582 putative cell division inhibitor YP_001477988.1 PFAM: TfoX domain protein; KEGG: yen:YE1583 hypothetical protein YP_001477989.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: yen:YE1584 hypothetical protein YP_001477990.1 PFAM: protein of unknown function DUF307; KEGG: yen:YE1585 hypothetical protein YP_001477991.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001477992.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001477993.1 KEGG: yen:YE1588 hypothetical protein YP_001477994.1 PFAM: CoA-binding domain protein; KEGG: yen:YE1589 hypothetical protein YP_001477995.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: ent:Ent638_1478 hemimethylated DNA binding protein YP_001477996.1 SMART: PUA domain containing protein; KEGG: yps:YPTB1463 hypothetical protein YP_001477997.1 PFAM: acylphosphatase; KEGG: yen:YE1596 putative acylphosphatase YP_001477998.1 PFAM: DsrC family protein; KEGG: ypi:YpsIP31758_2529 sulfurtransferase TusE YP_001477999.1 PFAM: protein of unknown function UPF0005; KEGG: eca:ECA1763 putative membrane protein YP_001478000.1 KEGG: ypi:YpsIP31758_0746 hypothetical protein YP_001478001.1 KEGG: ypi:YpsIP31758_0749 hypothetical protein YP_001478002.1 PFAM: protein of unknown function DUF1219; KEGG: yps:YPTB3866 hypothetical protein YP_001478003.1 PFAM: YagBYeeUYfjZ family protein; KEGG: yps:YPTB3867 hypothetical protein YP_001478004.1 PFAM: DNA repair protein RadC; KEGG: yps:YPTB3868 hypothetical protein YP_001478005.1 PFAM: Antirestriction protein; KEGG: ypi:YpsIP31758_0752 antirestriction protein, ArdB family YP_001478006.1 PFAM: O-antigen polymerase; KEGG: yen:YE1727 putative inner membrane protein YP_001478007.1 TIGRFAM: lipopolysaccharide heptosyltransferase III, putative; PFAM: glycosyl transferase family 9; KEGG: ypp:YPDSF_3215 lipopolysaccharide core biosynthesis protein YP_001478008.1 KEGG: aha:AHA_1082 hypothetical protein YP_001478012.1 KEGG: ecc:c3652 hypothetical protein YfjI YP_001478013.1 KEGG: ecc:c3648 hypothetical protein YP_001478014.1 PFAM: conserved hypothetical protein; KEGG: ent:Ent638_2916 uncharacterised conserved protein UCP028301 YP_001478015.1 PFAM: protein of unknown function DUF877; KEGG: ent:Ent638_2915 protein of unknown function DUF877 YP_001478016.1 PFAM: protein of unknown function DUF876; KEGG: kpn:KPN_01324 hypothetical protein YP_001478017.1 KEGG: kpn:KPN_01325 hypothetical protein YP_001478018.1 PFAM: OmpA/MotB domain protein; KEGG: kpn:KPN_01326 putative outer membrane protein YP_001478019.1 PFAM: protein of unknown function DUF796; KEGG: kpn:KPN_01327 hypothetical protein YP_001478020.1 PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: kpn:KPN_01328 putative protease YP_001478021.1 PFAM: Rhs element Vgr protein; KEGG: kpn:KPN_01329 hypothetical protein YP_001478022.1 KEGG: plu:plu3245 hypothetical protein YP_001478023.1 KEGG: plu:plu3242 hypothetical protein YP_001478024.1 KEGG: plu:plu3242 hypothetical protein YP_001478025.1 KEGG: plu:plu3243 hypothetical protein YP_001478026.1 KEGG: plu:plu3241 hypothetical protein YP_001478027.1 PFAM: PAAR repeat-containing protein; KEGG: plu:plu3240 hypothetical protein YP_001478028.1 KEGG: plu:plu3239 hypothetical protein YP_001478029.1 PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: kpn:KPN_01342 hypothetical protein YP_001478030.1 PFAM: ImpA domain protein; KEGG: ypi:YpsIP31758_2492 ImpA domain protein YP_001478031.1 PFAM: protein of unknown function DUF879; KEGG: kpn:KPN_01347 hypothetical protein YP_001478032.1 PFAM: protein of unknown function DUF1305; KEGG: ypi:YpsIP31758_0801 hypothetical protein YP_001478033.1 KEGG: ypi:YpsIP31758_2487 hypothetical protein YP_001478034.1 PFAM: GPW/gp25 family protein; KEGG: ypi:YpsIP31758_2486 hypothetical protein YP_001478035.1 PFAM: ImpA domain protein; KEGG: ent:Ent638_2906 ImpA domain protein YP_001478036.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: kpn:KPN_pKPN3p05958 secondary glycine betaine transporter BetU YP_001478038.1 PFAM: cytochrome c class I; KEGG: yen:YE1369 putative dehydrogenase, cytochrome c subunit YP_001478039.1 KEGG: yen:YE1370 putative dehydrogenase subunit YP_001478040.1 KEGG: yen:YE1370A putative dehydrogenase subunit YP_001478041.1 PFAM: DNA/RNA non-specific endonuclease; KEGG: ypi:YpsIP31758_B0090 putative endonuclease YP_001478042.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: ecv:APECO1_516 Rac prophage; potassium transporter subunit YP_001478044.1 stationary phase protein that binds TrpR repressor YP_001478045.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: aha:AHA_3853 transporter, LysE family YP_001478046.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_4583 CDA peptide synthetase I YP_001478047.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: ppf:Pput_3508 transcriptional regulator, XRE family YP_001478048.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pst:PSPTO_3470 hypothetical protein YP_001478049.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: yen:YE1944 putative membrane permease YP_001478050.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: yen:YE1945 4-hydroxyphenylacetate 3-monooxygenase coupling protein YP_001478051.1 PFAM: alpha/beta hydrolase fold; KEGG: yen:YE1947 putative hydrolase YP_001478052.1 PFAM: Endoribonuclease L-PSP; KEGG: yen:YE1948 hypothetical protein YP_001478053.1 PFAM: isochorismatase hydrolase; KEGG: yen:YE1949 putative isochorismatase YP_001478054.1 PFAM: luciferase family protein; KEGG: yen:YE1950 alkanesulfonate monooxygenase YP_001478055.1 PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: yen:YE1951 putative TetR-family transcriptional regulatory protein YP_001478056.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001478057.1 KEGG: ypi:YpsIP31758_0269 DedA family protein YP_001478058.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE3018 hypothetical protein YP_001478059.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV1350 putative enoyl-CoA hydratase YP_001478060.1 PFAM: major facilitator superfamily MFS_1; KEGG: rru:Rru_A0797 major facilitator transporter superfamily MFS_1 YP_001478061.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001478062.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: csa:Csal_0301 beta-ketoadipyl CoA thiolase YP_001478063.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: pin:Ping_0657 3-hydroxybutyryl-CoA dehydrogenase YP_001478064.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: bvi:Bcep1808_6456 autoinducer-binding domain protein YP_001478065.1 PFAM: UspA domain protein; KEGG: eca:ECA1769 hypothetical protein YP_001478066.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: kpn:KPN_04791 putative dehydrogenase YP_001478067.1 PFAM: amino acid permease-associated region; KEGG: pfl:PFL_1414 amino acid transporter, putative YP_001478068.1 PFAM: aldehyde dehydrogenase; KEGG: pae:PA2217 probable aldehyde dehydrogenase YP_001478069.1 PFAM: dihydrodipicolinate synthetase; KEGG: bch:Bcen2424_4139 dihydrodipicolinate synthetase YP_001478070.1 PFAM: helix-turn-helix- domain containing protein AraC type; PAS fold-4 domain protein; KEGG: plu:plu2244 hypothetical protein YP_001478071.1 PFAM: proline racemase; KEGG: pap:PSPA7_4122 hypothetical protein YP_001478072.1 PFAM: FAD dependent oxidoreductase; KEGG: plu:plu2242 hypothetical protein YP_001478073.1 PFAM: ferredoxin; KEGG: bam:Bamb_3552 ferredoxin YP_001478074.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bur:Bcep18194_B1891 pyridine nucleotide-disulphide oxidoreductase YP_001478075.1 KEGG: plu:plu3625 hypothetical protein YP_001478077.1 KEGG: yen:YE2300 hypothetical protein YP_001478078.1 KEGG: yen:YE1832 hypothetical protein YP_001478079.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001478080.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001478081.1 KEGG: ypi:YpsIP31758_2251 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001478082.1 KEGG: plu:plu2537 hypothetical protein YP_001478083.1 SMART: helix-turn-helix domain protein; KEGG: plu:plu2536 hypothetical protein YP_001478085.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: pfo:Pfl_0722 transcriptional regulator, RpiR family YP_001478086.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: plu:plu2754 PTS system, cellobiose-specific IIB component YP_001478087.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: kpn:KPN_04368 putative PEP-dependent phosphotransferase enzyme III YP_001478088.1 PFAM: glycoside hydrolase family 4; KEGG: ypi:YpsIP31758_3951 6-phospho-beta-glucosidase YP_001478089.1 KEGG: kpn:KPN_04650 putative phosphotransferase protein; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PTS system, cellobiose-specific IIC subunit; PFAM: phosphotransferase system EIIC YP_001478090.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001478091.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; Osmosensory transporter coiled coil; KEGG: yen:YE3594 proline/betaine transporter YP_001478092.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: ppd:Ppro_2218 RND efflux system, outer membrane lipoprotein, NodT family YP_001478093.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: sgl:SG1459 putative ABC transporter ATP-binding component YP_001478094.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sgl:SG1458 putative secretion protein YP_001478095.1 KEGG: sgl:SG1153 hypothetical protein YP_001478096.1 KEGG: yen:YE2596 hypothetical protein YP_001478098.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001478099.1 KEGG: yen:YE1603 hypothetical protein YP_001478100.1 required for the transfer of succinyl residues to the glucan backbone YP_001478101.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001478102.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001478103.1 PFAM: protein of unknown function DUF1375; KEGG: yps:YPTB2492 hypothetical protein YP_001478104.1 KEGG: bte:BTH_II1582 hypothetical protein YP_001478105.1 KEGG: spt:SPA1698 acidic protein MsyB; multicopy suppressor of SecY YP_001478106.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: kpn:KPN_03016 putative isopropylmalate/homocitrate/citramalate synthase YP_001478107.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: ent:Ent638_3166 transcriptional regulator, AraC family YP_001478108.1 PFAM: regulatory protein ArsR; KEGG: cvi:CV_0084 probable transcriptional regulator, ArsR family YP_001478109.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: cvi:CV_0083 hypothetical protein YP_001478110.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: nmu:Nmul_A1684 YeeE/YedE YP_001478111.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vfi:VFA0660 prolyl endopeptidase YP_001478112.1 KEGG: ent:Ent638_0823 amino acid/peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001478113.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1610 putative MFS-family transport protein YP_001478114.1 PFAM: YCII-related; KEGG: yen:YE1740 hypothetical protein YP_001478115.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001478116.1 KEGG: eca:ECA1780 putative NADH-dependent flavin oxidoreductase YP_001478117.1 PFAM: Rhodanese domain protein; KEGG: ypi:YpsIP31758_1560 rhodanese domain protein YP_001478118.1 PFAM: YceI family protein; KEGG: yen:YE1254 hypothetical protein YP_001478119.1 PFAM: cytochrome B561; KEGG: yen:YE1253 hypothetical protein YP_001478120.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001478121.1 KEGG: ypi:YpsIP31758_1562 hypothetical protein YP_001478122.1 PFAM: regulatory protein LuxR; KEGG: yen:YE1621 putative LuxR-family regulatory protein YP_001478123.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001478124.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001478125.1 KEGG: eca:ECA1785 hypothetical protein YP_001478126.1 PFAM: DinI family protein; KEGG: yen:YE1624 DNA-damage-inducible protein I YP_001478127.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001478128.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE1626 hypothetical protein YP_001478129.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001478130.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001478131.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: ent:Ent638_1602 maf protein YP_001478132.1 PFAM: protein of unknown function DUF177; KEGG: yen:YE1630 hypothetical protein YP_001478133.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001478134.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001478135.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001478136.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: yen:YE1634 malonyl CoA-acyl carrier protein transacylase YP_001478137.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001478138.1 carries the fatty acid chain in fatty acid biosynthesis YP_001478139.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001478140.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001478141.1 PFAM: aminodeoxychorismate lyase; KEGG: yen:YE1639 hypothetical protein YP_001478142.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001478143.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001478144.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: yen:YE1642 putative deoxyribonuclease YP_001478145.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001478146.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001478147.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: bbt:BBta_1556 manganese/divalent cation transport protein (NRAMP family) YP_001478148.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: yen:YE3354 putative oxidoreductase YP_001478149.1 PFAM: helix-turn-helix HxlR type; KEGG: eca:ECA0746 putative transcriptional regulator YP_001478150.1 PFAM: extracellular solute-binding protein family 3; KEGG: eca:ECA2157 ABC transporter, substrate binding protein YP_001478151.1 PFAM: histidine triad (HIT) protein; KEGG: ypi:YpsIP31758_1588 histidine triad nucleotide-binding protein HinT YP_001478152.1 PFAM: protein of unknown function DUF1425; KEGG: ypi:YpsIP31758_1589 putative lipoprotein YP_001478153.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: eca:ECA1811 putative lipoprotein YP_001478154.1 PFAM: aminoglycoside phosphotransferase; KEGG: ypi:YpsIP31758_1591 thiamine kinase YP_001478155.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001478156.1 PFAM: protein of unknown function UPF0227; KEGG: ypi:YpsIP31758_1593 hypothetical protein YP_001478157.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: yen:YE1707 NADH dehydrogenase YP_001478158.1 PFAM: 17 kDa surface antigen; KEGG: eci:UTI89_C1238 hypothetical protein YcfJ YP_001478159.1 PFAM: protein of unknown function UPF0074; KEGG: kpn:KPN_02971 putative transcriptional regulator YP_001478160.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: kpn:KPN_02970 integral transmembrane protein; acridine resistance YP_001478161.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ent:Ent638_1891 efflux transporter, RND family, MFP subunit YP_001478162.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: kpn:KPN_02968 putative helix-turn-helix, AraC type YP_001478163.1 KEGG: lpc:LPC_0954 peptide transport protein; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001478164.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yen:YE2422 putative oxidoreductase YP_001478165.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypi:YpsIP31758_2053 putative phosphoesterase YP_001478166.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein YP_001478167.1 PFAM: protein of unknown function DUF533; KEGG: eca:ECA1747 hypothetical protein YP_001478168.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: yen:YE1789 oligopeptidase B YP_001478169.1 3'-5' exonuclease activity on single or double-strand DNA YP_001478170.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: pap:PSPA7_6338 RNA polymerase-binding protein DksA YP_001478171.1 KEGG: ypp:YPDSF_1342 proline iminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_001478172.1 PFAM: DNA polymerase II beta subunit; KEGG: eca:ECA2475 DNA polymerase III, theta subunit YP_001478173.1 PFAM: Ferritin Dps family protein; KEGG: yen:YE1795 ferritin YP_001478174.1 PFAM: copper resistance protein CopC; KEGG: yen:YE1796 putative copper resistance protein YP_001478175.1 PFAM: copper resistance D domain protein; KEGG: ypi:YpsIP31758_2338 copper resistance protein D YP_001478176.1 KEGG: yen:YE1798 hypothetical protein YP_001478177.1 PFAM: GCN5-related N-acetyltransferase; KEGG: kpn:KPN_00583 putative GCN5-related N-acetyltransferase YP_001478178.1 KEGG: bpe:BP2072 putative lipoprotein YP_001478179.1 KEGG: asa:ASA_2363 hypothetical protein YP_001478180.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001478181.1 KEGG: plu:plu3628 hypothetical protein YP_001478182.1 PFAM: helix-turn-helix domain protein; KEGG: rpe:RPE_4746 transcriptional regulator, XRE family YP_001478186.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pap:PSPA7_4416 transcriptional regulator, LysR family YP_001478187.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pap:PSPA7_4414 aryl-alcohol dehydrogenase (benzyl alcoholdehydrogenase) (badh) YP_001478188.1 KEGG: pap:PSPA7_4413 hypothetical protein YP_001478189.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001478190.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001478191.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sme:SMb20498 hypothetical protein YP_001478192.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_00509 putative periplasmic binding protein YP_001478193.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_00510 putative ABC transporter YP_001478194.1 PFAM: inner-membrane translocator; KEGG: kpn:KPN_00511 putative bacterial inner-membrane translocator YP_001478195.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hch:HCH_01166 ABC-type sugar transport system, periplasmic component YP_001478196.1 KEGG: mem:Memar_0550 hypothetical protein YP_001478197.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: spt:SPA0252 putative lipoprotein precursor YP_001478198.1 KEGG: aba:Acid345_3568 hypothetical protein YP_001478199.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: stm:STM3820 putative cytochrome c peroxidase YP_001478200.1 PFAM: UspA domain protein; KEGG: ppr:PBPRA0125 putative universal stress protein A YP_001478201.1 KEGG: vvy:VV2646 putative isomerase YP_001478202.1 KEGG: ecs:ECs3961 hypothetical protein YP_001478203.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ecj:JW3046 DNA-binding transcriptional repressor YP_001478204.1 in Escherichia coli this is the second beta-galactosidase system YP_001478205.1 in Escherichia coli this is the second beta-galactosidase system YP_001478206.1 PFAM: amino acid permease-associated region; KEGG: ecp:ECP_3169 hypothetical transporter YgjI YP_001478207.1 PFAM: regulatory protein ArsR; KEGG: rle:RL1168 putative HTH family transcriptional regulator YP_001478208.1 KEGG: sme:SMc03842 hypothetical protein YP_001478209.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001478210.1 KEGG: pen:PSEEN4400 hypothetical protein YP_001478211.1 KEGG: pen:PSEEN4401 hypothetical protein YP_001478212.1 KEGG: sfu:Sfum_1629 hypothetical protein YP_001478213.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001478214.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: nis:NIS_1014 sulfate transporter YP_001478215.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001478216.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001478217.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001478218.1 KEGG: ypi:YpsIP31758_2069 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein YP_001478219.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001478220.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001478221.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001478222.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001478223.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: yen:YE2429 hypothetical protein YP_001478224.1 KEGG: yen:YE2428 hypothetical protein YP_001478225.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001478226.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001478227.1 PFAM: protein of unknown function DUF336; KEGG: yen:YE1367 hypothetical protein YP_001478228.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: yen:YE2425 putative inner membrane protein YP_001478229.1 KEGG: yen:YE1709 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001478230.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pol:Bpro_3215 pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001478231.1 PFAM: YheO domain protein; KEGG: yen:YE3210 hypothetical protein YP_001478232.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001478233.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001478234.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001478235.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001478236.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001478237.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: kpn:KPN_04017 putative sugar isomerase YP_001478238.1 PFAM: glycoside hydrolase family 4; KEGG: kpn:KPN_04016 putative glycoside hydrolase, family 4 YP_001478239.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: kpn:KPN_04015 phosphotransferase system PTS YP_001478240.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001478241.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: ecv:APECO1_1289 hypothetical oxidoreductase YP_001478242.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: yen:YE1716 hypothetical protein YP_001478243.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: yen:YE1717 sensor protein kinase YP_001478244.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001478245.1 PFAM: cytochrome c class I; KEGG: pap:PSPA7_2974 probable cytochrome c precursor YP_001478246.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: bxe:Bxe_A4095 putative gluconate dehydrogenase YP_001478247.1 KEGG: bam:Bamb_3645 hypothetical protein YP_001478248.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: oan:Oant_4139 putative transcriptional regulator, GntR family YP_001478249.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pcr:Pcryo_0836 GCN5-related N-acetyltransferase YP_001478250.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE2480 putative acetyltransferase YP_001478251.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001478252.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001478253.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001478254.1 PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_1613 hydrolase, NUDIX family YP_001478255.1 PFAM: pseudouridine synthase; KEGG: yen:YE1724 putative pseudouridine synthase YP_001478256.1 Converts isocitrate to alpha ketoglutarate YP_001478258.1 KEGG: ava:Ava_2063 hypothetical protein YP_001478259.1 PFAM: integrase family protein; KEGG: ecj:JW1126 predicted integrase YP_001478260.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001478261.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001478263.1 KEGG: ent:Ent638_2623 hypothetical protein YP_001478264.1 KEGG: sit:TM1040_1659 hypothetical protein YP_001478265.1 PFAM: peptidase S24 and S26 domain protein; KEGG: ent:Ent638_2620 putative phage repressor YP_001478266.1 KEGG: plu:plu3476 hypothetical protein YP_001478267.1 KEGG: sec:SC0986 Gifsy-2 prophage lysozyme YP_001478271.1 PFAM: DNA polymerase II beta subunit; KEGG: plu:plu2690 DNA polymerase III, theta subunit YP_001478272.1 PFAM: DNA packaging Nu1; KEGG: ssn:SSON_2431 bacteriophage DNA packaging protein YP_001478273.1 PFAM: terminase GpA; KEGG: ecs:ECs1630 terminase large subunit YP_001478274.1 KEGG: tcx:Tcr_0695 phage tail sheath protein YP_001478275.1 PFAM: P2 GpU family protein; KEGG: syf:Synpcc7942_0751 hypothetical protein YP_001478276.1 PFAM: late control D family protein; KEGG: sdy:SDY_1080 hypothetical protein YP_001478277.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: ent:Ent638_0915 putative transcriptional regulator, AsnC family YP_001478278.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: stt:t1016 putative membrane protein YP_001478279.1 KEGG: yen:YE1725 isocitrate dehydrogenase YP_001478280.1 KEGG: kpn:KPN_00743 cell envelope integrity inner membrane protein TolA YP_001478281.1 PFAM: protein of unknown function UPF0118; KEGG: eca:ECA0120 hypothetical protein YP_001478282.1 TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: pen:PSEEN1931 4-oxalocrotonate tautomerase YP_001478283.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pol:Bpro_3414 short-chain dehydrogenase/reductase SDR YP_001478284.1 PFAM: regulatory protein LacI; KEGG: kpn:KPN_01795 putative periplasmic binding protein/LacI transcriptional regulator YP_001478285.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_01796 putative epimerase/isomerase YP_001478286.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: kpn:KPN_01797 hypothetical oxidoreductase YP_001478287.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: swi:Swit_2158 glutathione-dependent formaldehyde-activating, GFA YP_001478289.1 PFAM: Domain of unknown function DUF1835; KEGG: bat:BAS2610 hypothetical protein YP_001478290.1 PFAM: pentapeptide repeat protein; KEGG: ppr:PBPRB0125 hypothetical protein YP_001478292.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eca:ECA2471 cold shock protein YP_001478293.1 PFAM: isochorismatase hydrolase; KEGG: bbr:BB1080 putative isochorismatase YP_001478294.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vco:VC0395_A1193 oxidoreductase, short-chain dehydrogenase/reductase family YP_001478295.1 PFAM: FAD dependent oxidoreductase; KEGG: kpn:KPN_01017 probable oxidoreductase YP_001478296.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_001478297.1 regulates genes involved in putrescine degradation YP_001478298.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_001478299.1 PFAM: glutamine synthetase catalytic region; KEGG: ecs:ECs1874 putative glutamine synthetase YP_001478300.1 PFAM: amino acid permease-associated region; KEGG: kpn:KPN_01022 putative amino acid/amine transport protein YP_001478301.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ent:Ent638_2056 protein of unknown function DUF6, transmembrane YP_001478303.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: ecv:APECO1_1599 nucleoside-specific channel-forming protein Tsx YP_001478304.1 KEGG: kpn:KPN_02024 hypothetical protein YP_001478305.1 catalyzes the interconversion of chorismate to prephenate YP_001478306.1 PFAM: beta-lactamase; KEGG: oan:Oant_3736 beta-lactamase YP_001478307.1 PFAM: N-formylglutamate amidohydrolase; KEGG: yen:YE2462 putative N-formylglutamate amidohydrolase YP_001478308.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001478309.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: yen:YE2460 putative GntR-family transcriptional regulatory protein YP_001478310.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001478311.1 PFAM: protein of unknown function DUF886; KEGG: yen:YE2458 hypothetical protein YP_001478312.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_03263 putative bacterial regulatory protein, LacI YP_001478313.1 KEGG: sdy:SDY_2558 sucrose hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32 YP_001478314.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001478315.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ent:Ent638_0364 major facilitator superfamily MFS_1 YP_001478316.1 PFAM: cytochrome c class I; KEGG: yen:YE1086 putative cytochrome c YP_001478317.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: har:HEAR2557 glucose dehydrogenase YP_001478318.1 KEGG: pfo:Pfl_4264 twin-arginine translocation pathway signal YP_001478319.1 PFAM: protein of unknown function DUF336; KEGG: pmy:Pmen_0200 protein of unknown function DUF336 YP_001478320.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; Phosphogluconate dehydrogenase, NAD-binding, putative-like; KEGG: kpn:KPN_04046 putative dehydrogenase YP_001478321.1 PFAM: protein of unknown function DUF453; KEGG: kpn:KPN_04047 hypothetical protein YP_001478322.1 TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; PFAM: Dimethylmenaquinone methyltransferase; KEGG: ppf:Pput_3204 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase YP_001478323.1 PFAM: LmbE family protein; KEGG: ppf:Pput_1362 LmbE family protein YP_001478324.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppu:PP_2516 transcriptional regulator, LysR family YP_001478325.1 KEGG: pen:PSEEN2021 3-dehydroquinate dehydratase, type II; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: dehydroquinase class II YP_001478326.1 PFAM: amidohydrolase 2; KEGG: ppf:Pput_2198 amidohydrolase 2 YP_001478327.1 extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway YP_001478328.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_04052 putative general substrate transporter YP_001478329.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001478330.1 PFAM: Citrate carrier protein; KEGG: yen:YE2507 putative citrate/sodium-family symporter YP_001478335.1 PFAM: protein of unknown function DUF437; KEGG: yen:YE1853 hypothetical protein YP_001478336.1 KEGG: rle:RL2800 hypothetical protein YP_001478337.1 PFAM: protein of unknown function DUF1480; KEGG: ypi:YpsIP31758_1660 hypothetical protein YP_001478338.1 PFAM: Spore coat U domain protein; KEGG: yen:YE1856 hypothetical protein YP_001478339.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yen:YE1857 probable outer membrane usher protein YP_001478340.1 KEGG: yen:YE1858 putative chaperone protein YP_001478341.1 PFAM: Spore coat U domain protein; KEGG: yen:YE1859 hypothetical protein YP_001478342.1 PFAM: Spore coat U domain protein; KEGG: yps:YPTB2382 hypothetical protein YP_001478343.1 PFAM: Spore coat U domain protein; KEGG: yen:YE1861 hypothetical protein YP_001478344.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001478345.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: yen:YE1865 hypothetical protein YP_001478346.1 PFAM: GAF domain protein; KEGG: ypi:YpsIP31758_1670 hypothetical protein YP_001478347.1 affects solute and DNA transport through an unknown mechanism YP_001478348.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001478349.1 putative metalloprotease YP_001478350.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1875 putative transport protein YP_001478351.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: yen:YE1877 IclR-family transcriptional regulatory protein YP_001478352.1 PFAM: sodium:dicarboxylate symporter; KEGG: yen:YE1879 putative transport protein YP_001478353.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: yen:YE1880 hypothetical protein YP_001478354.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001478355.1 KEGG: xau:Xaut_4145 conserved hypothetical membrane-bound protease YP_001478356.1 KEGG: yen:YE1891 putative yfeABCD locus regulator YP_001478357.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: yen:YE1896 hypothetical protein YP_001478358.1 PFAM: GCN5-related N-acetyltransferase; KEGG: plu:plu3509 hypothetical protein YP_001478359.1 PFAM: ABC-3 protein; KEGG: yen:YE1897 chelated iron transport system membrane protein YP_001478360.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: ypi:YpsIP31758_1703 chelated iron ABC transporter, permease protein YfeC YP_001478361.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE1899 ATP-binding transport protein YP_001478362.1 PFAM: periplasmic solute binding protein; KEGG: eca:ECA2392 periplasmic chelated iron-binding protein YP_001478363.1 KEGG: kpn:KPN_02184 hypothetical protein YP_001478364.1 PFAM: Lytic transglycosylase catalytic; KEGG: yps:YPTB2346 putative membrane-bound lytic murein transglycosylase YP_001478365.1 KEGG: kpn:KPN_02084 hypothetical protein YP_001478366.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: kpn:KPN_02083 monooxygenase, FAD-binding; glucose-methanol-choline oxidoreductase YP_001478367.1 PFAM: cytochrome c class I; KEGG: kpn:KPN_02082 gluconate dehydrogenase cytochrome c subunit, putative YP_001478368.1 KEGG: asa:ASA_3891 serine transporter YP_001478369.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3241 ABC transporter, substrate binding protein YP_001478370.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001478372.1 KEGG: plu:plu2637 hypothetical protein YP_001478373.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001478374.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001478375.1 PFAM: ribosomal protein L35; KEGG: yen:YE1914 50S ribosomal protein L35 YP_001478376.1 TIGRFAM: ribosomal protein L20; KEGG: ypi:YpsIP31758_1715 ribosomal protein L20 YP_001478377.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001478378.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001478379.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001478380.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001478381.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001478382.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001478383.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001478384.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001478385.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001478386.1 PFAM: polysaccharide deacetylase; KEGG: yen:YE2189 hypothetical protein YP_001478387.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001478388.1 KEGG: yen:YE2187 hypothetical protein YP_001478389.1 KEGG: ypi:YpsIP31758_1731 hypothetical protein YP_001478390.1 PFAM: NLP/P60 protein; KEGG: yen:YE2185 putative lipoprotein YP_001478391.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001478392.1 PFAM: EAL domain protein; KEGG: eca:ECA1841 hypothetical protein YP_001478393.1 PFAM: protein of unknown function UPF0061; KEGG: ypi:YpsIP31758_1734 hypothetical protein YP_001478394.1 with HmuTU is involved in the transport of hemin YP_001478395.1 PFAM: transport system permease protein; KEGG: yen:YE0328 hemin transport system permease protein HmuU YP_001478396.1 PFAM: periplasmic binding protein; KEGG: ypi:YpsIP31758_3803 hemin ABC transporter, periplasmic hemin-binding protein YP_001478397.1 PFAM: Haemin-degrading family protein; KEGG: yen:YE0330 hemin transport protein YP_001478398.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yen:YE0331 hemin receptor precursor YP_001478399.1 KEGG: yen:YE0332 hemin uptake protein YP_001478400.1 PFAM: glutathione peroxidase; KEGG: pae:PA2826 probable glutathione peroxidase YP_001478401.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001478402.1 PFAM: protein of unknown function DUF299; KEGG: yen:YE2177 hypothetical protein YP_001478403.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001478404.1 PFAM: protein of unknown function UPF0118; KEGG: ypi:YpsIP31758_1738 hypothetical protein YP_001478405.1 PFAM: FAD linked oxidase domain protein; KEGG: yen:YE2174 hypothetical protein YP_001478406.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA1857 hypothetical protein YP_001478407.1 KEGG: eca:ECA1858 hypothetical protein YP_001478408.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001478409.1 with SufCD activates cysteine desulfurase SufS YP_001478410.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001478411.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: ypi:YpsIP31758_1744 FeS assembly protein SufD YP_001478412.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ypp:YPDSF_0748 selenocysteine lyase YP_001478413.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001478414.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: yen:YE2166 hypothetical protein YP_001478415.1 PFAM: LPP repeat-containing protein; KEGG: yen:YE2165 major outer membrane lipoprotein YP_001478416.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001478417.1 KEGG: ent:Ent638_3287 cupin 2, conserved barrel domain protein YP_001478418.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001478419.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001478420.1 KEGG: rsq:Rsph17025_0056 hypothetical protein YP_001478421.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001478422.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001478423.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_0759 LysR-family transcriptional regulatory protein YP_001478424.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001478425.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001478426.1 PFAM: NLP/P60 protein; KEGG: yen:YE2156 hypothetical protein YP_001478427.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: ypi:YpsIP31758_1758 monothiol glutaredoxin GrxD YP_001478428.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001478429.1 KEGG: yen:YE2153 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001478430.1 KEGG: plu:plu3987 unnamed protein product; some similarities with isopentenyl-diphosphate delta-isomerase (IPP isomerase) (isopentenyl pyrophosphate isomerase); TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1; PFAM: NUDIX hydrolase YP_001478431.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001478432.1 PFAM: regulatory protein TetR; KEGG: yen:YE2151 TetR-family transcriptional regulatory protein YP_001478433.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001478434.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: pmy:Pmen_0809 3-beta hydroxysteroid dehydrogenase/isomerase YP_001478435.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pmy:Pmen_0810 transcriptional regulator, LysR family YP_001478436.1 PFAM: protein of unknown function DUF1289; KEGG: yen:YE2149 hypothetical protein YP_001478437.1 PFAM: aldo/keto reductase; KEGG: yen:YE2148 putative aldo/keto reductase YP_001478438.1 PFAM: Hemolysin-type calcium-binding region; lipase class 3; KEGG: plu:plu2313 hypothetical protein YP_001478439.1 PFAM: superoxide dismutase copper/zinc binding; KEGG: psp:PSPPH_1224 superoxide dismutase, Cu-Zn YP_001478440.1 PFAM: Fusaric acid resistance protein conserved region; KEGG: yen:YE2147 hypothetical protein YP_001478441.1 PFAM: secretion protein HlyD family protein; KEGG: yen:YE2146 putative HlyD-family protein YP_001478442.1 PFAM: protein of unknown function DUF1656; KEGG: yen:YE2145 putative inner membrane protein YP_001478443.1 Transcription regulator that can both activate or repress expression YP_001478444.1 PFAM: 17 kDa surface antigen; KEGG: sgl:SG1444 outer membrane lipoprotein YP_001478445.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001478446.1 KEGG: yen:YE2141 putative lipoprotein YP_001478447.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001478448.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001478449.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001478450.1 PFAM: Glutathione S-transferase domain; KEGG: yen:YE2137 glutathione S-transferase YP_001478451.1 TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; KEGG: pfl:PFL_3321 dihydrodipicolinate synthase YP_001478452.1 KEGG: yen:YE2136 hypothetical protein YP_001478453.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sme:SMc02632 hypothetical protein YP_001478454.1 KEGG: cvi:CV_2861 hypothetical protein YP_001478455.1 PFAM: Endoribonuclease L-PSP; KEGG: vpa:VP1797 hypothetical protein YP_001478456.1 PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: pau:PA14_40450 streptomycin 3''-phosphotransferase YP_001478457.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: psp:PSPPH_1841 auxin-binding protein, putative YP_001478458.1 PFAM: MEKHLA domain protein; KEGG: psb:Psyr_0755 hypothetical protein YP_001478459.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: plu:plu0511 unnamed protein product; highly similar to benzoate membrane transport protein YP_001478460.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: eca:ECA4472 putative DNA-binding protein YP_001478461.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: xcv:XCV0685 putative prolyl oligopeptidase precursor YP_001478462.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001478463.1 KEGG: kpn:KPN_01970 endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001478464.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001478465.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001478466.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001478467.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1991 putative AraC-family transcriptional regulatory protein YP_001478468.1 TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: ypi:YpsIP31758_1896 electron transport complex, RnfABCDGE type, C subunit YP_001478469.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001478470.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: yen:YE1994 hypothetical protein YP_001478471.1 KEGG: yen:YE1996 hypothetical protein YP_001478472.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001478473.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001478474.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE2003 L-arabinose-binding periplasmic protein precursor YP_001478475.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001478476.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001478477.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001478478.1 PFAM: Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain protein; Oxidoreductase domain; KEGG: yen:YE2007 putative oxidoreductase YP_001478479.1 KEGG: yen:YE2008 hypothetical protein YP_001478480.1 catalyzes the formation of inosine from adenosine YP_001478481.1 KEGG: kpn:KPN_04198 putative serine protease YP_001478482.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: kpn:KPN_04197 putative PTS family enzyme IIA component YP_001478483.1 KEGG: eca:ECA2355 hypothetical protein YP_001478484.1 KEGG: kpn:KPN_04196 putative ketose-bisphosphate aldolase, class-II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II YP_001478485.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001478486.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: kpn:KPN_04194 putative PTS family enzyme II component YP_001478487.1 PFAM: phosphofructokinase; KEGG: kpn:KPN_04193 putative 6-phosphofructokinase YP_001478488.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: bch:Bcen2424_0941 transcriptional regulator, DeoR family YP_001478489.1 PFAM: NUDIX hydrolase; KEGG: bvi:Bcep1808_0859 NUDIX hydrolase YP_001478490.1 KEGG: bch:Bcen2424_0943 hypothetical protein YP_001478491.1 PFAM: aminotransferase class I and II; KEGG: yen:YE2010 putative aminotransferase YP_001478492.1 TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, maltose and glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component YP_001478493.1 PFAM: integrase family protein; KEGG: yen:YE2364 putative phage integrase YP_001478494.1 PFAM: protein of unknown function DUF1233 excisionase putative; KEGG: ypm:YP_1930 putative phage excisionase YP_001478495.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001478496.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001478497.1 PFAM: acyltransferase 3; KEGG: ret:RHE_CH00500 probable acyltransferase protein YP_001478498.1 PFAM: lipolytic protein G-D-S-L family; KEGG: vvu:VV1_1768 lysophospholipase L1 YP_001478499.1 KEGG: yen:YE2011 PTS system, maltose and glucose-specific IIAbc component YP_001478500.1 regulates malXY which are involved in maltose-glucose transport YP_001478501.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bam:Bamb_4361 transcriptional regulator, LysR family YP_001478502.1 PFAM: beta-lactamase; KEGG: sbl:Sbal_2086 beta-lactamase YP_001478503.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vpa:VP1676 putative transcriptional regulator YP_001478504.1 PFAM: beta-lactamase; KEGG: bpd:BURPS668_A1860 putative esterase YP_001478505.1 PFAM: protein of unknown function DUF945; KEGG: yen:YE2014 hypothetical protein YP_001478506.1 TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: yen:YE2015 mannose-6-phosphate isomerase YP_001478507.1 KEGG: reu:Reut_A2446 probable signal peptide protein YP_001478508.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001478509.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001478510.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE2021 hypothetical protein YP_001478511.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2022 probable LysR-family transcriptional regulator YP_001478512.1 PFAM: ROK family protein; KEGG: yen:YE2023 putative ROK family transcriptional regulatory protein YP_001478513.1 KEGG: yen:YE2024 putative dethiobiotin synthetase; TIGRFAM: dethiobiotin synthase; PFAM: Cobyrinic acid ac-diamide synthase YP_001478514.1 PFAM: Chloride channel core; KEGG: yen:YE2025 hypothetical protein YP_001478515.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2256 putative transporter YP_001478516.1 PFAM: protein of unknown function DUF1161; KEGG: ypi:YpsIP31758_1866 putative lipoprotein YP_001478517.1 PFAM: protein of unknown function DUF1283; KEGG: yen:YE2026 hypothetical protein YP_001478518.1 PFAM: protein of unknown function UPF0060; KEGG: yen:YE2027 hypothetical protein YP_001478519.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001478520.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bch:Bcen2424_3796 GCN5-related N-acetyltransferase YP_001478521.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE2029 putative membrane transport protein YP_001478522.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: vei:Veis_1240 ABC transporter related YP_001478523.1 PFAM: PfkB domain protein; KEGG: ret:RHE_CH03378 probable sugar kinase protein YP_001478524.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21219 putative sugar uptake ABC transporter permease protein YP_001478525.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: smd:Smed_4556 binding-protein-dependent transport systems inner membrane component YP_001478526.1 PFAM: extracellular solute-binding protein family 1; KEGG: ret:RHE_CH03374 probable sugar ABC transporter, substrate-binding protein YP_001478527.1 PFAM: ROK family protein; KEGG: cvi:CV_2895 probable transcriptional regulator protein YP_001478528.1 TIGRFAM: Guanine deaminase; PFAM: amidohydrolase; KEGG: ppr:PBPRA1930 putative guanine aminohydrolase YP_001478529.1 TIGRFAM: Xanthine dehydrogenase small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: pst:PSPTO_3660 xanthine dehydrogenase, N-terminal subunit YP_001478530.1 KEGG: pau:PA14_44740 xanthine dehydrogenase; TIGRFAM: Xanthine dehydrogenase molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding YP_001478531.1 TIGRFAM: Xanthine dehydrogenase accessory protein XdhC; PFAM: protein of unknown function DUF182; KEGG: pau:PA14_44760 putative xanthine dehydrogenase accessory factor X YP_001478532.1 KEGG: vei:Veis_4629 fumarylacetoacetate (FAA) hydrolase YP_001478533.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vei:Veis_4630 glyoxalase/bleomycin resistance protein/dioxygenase YP_001478534.1 PFAM: alpha/beta hydrolase fold; KEGG: bvi:Bcep1808_4725 alpha/beta hydrolase fold YP_001478535.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: xac:XAC0249 peptidyl-dipeptidase YP_001478536.1 PFAM: major facilitator superfamily MFS_1; KEGG: ppu:PP_3940 major facilitator family transporter YP_001478537.1 PFAM: isochorismatase hydrolase; KEGG: ppf:Pput_1896 isochorismatase hydrolase YP_001478538.1 PFAM: Asp/Glu racemase; KEGG: ppf:Pput_1895 Asp/Glu racemase YP_001478539.1 PFAM: alpha/beta hydrolase fold; KEGG: ppu:PP_3943 hydrolase, alpha/beta fold family YP_001478540.1 PFAM: monooxygenase FAD-binding; KEGG: ppf:Pput_1893 monooxygenase, FAD-binding YP_001478541.1 KEGG: ppf:Pput_1892 hypothetical protein YP_001478542.1 PFAM: regulatory protein MarR; KEGG: reu:Reut_A2508 regulatory protein, MarR YP_001478543.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_1890 (2Fe-2S)-binding domain protein YP_001478544.1 PFAM: cytochrome c class I; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: ppu:PP_3948 aldehyde dehydrogenase family protein, putative/cytochrome c family protein, putative YP_001478545.1 PFAM: secretion protein HlyD family protein; KEGG: pau:PA14_10350 putative secretion protein YP_001478546.1 PFAM: ABC transporter transmembrane region; ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase; KEGG: bps:BPSL3093 colicin V processing peptidase YP_001478547.1 PFAM: monooxygenase FAD-binding; KEGG: kpn:KPN_01663 putative flavoprotein monooxygenase YP_001478548.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: swi:Swit_3976 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001478549.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: bch:Bcen2424_4406 (2Fe-2S)-binding domain protein YP_001478550.1 PFAM: cytochrome c class I; KEGG: bch:Bcen2424_5380 cytochrome c, class I YP_001478551.1 PFAM: Cupin domain protein; Cupin 2 conserved barrel domain protein; KEGG: plu:plu2325 putative oxalate decarboxylase YP_001478552.1 TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: eca:ECA0860 PTS system, IIabc component YP_001478553.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0859 beta-glucosidase YP_001478554.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: eca:ECA0858 putative beta-glucoside operon antiterminator YP_001478555.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_1186 transcriptional regulator, LysR family YP_001478556.1 PFAM: Chromate transporter; KEGG: bbr:BB1316 putative chromate transporter YP_001478557.1 PFAM: Chromate transporter; KEGG: bxe:Bxe_B2837 chromate transporter YP_001478558.1 PFAM: metalloprotease inhibitor I38; KEGG: eca:ECA2784 protease inhibitor YP_001478559.1 KEGG: rso:RSc1273 putative lipoprotein YP_001478560.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pcr:Pcryo_1332 GCN5-related N-acetyltransferase YP_001478561.1 PFAM: alpha/beta hydrolase fold; KEGG: pst:PSPTO_3264 hydrolase, alpha/beta fold family YP_001478562.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: bch:Bcen2424_4610 glucose-methanol-choline oxidoreductase YP_001478563.1 KEGG: bch:Bcen2424_4611 hypothetical protein YP_001478564.1 PFAM: cytochrome c class I; KEGG: bch:Bcen2424_4612 cytochrome c, class I YP_001478565.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yen:YE1742 putative inner membrane protein YP_001478566.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1743 putative AraC-family transcriptional regulatory protein YP_001478567.1 KEGG: eca:ECA2819 hypothetical protein YP_001478568.1 PFAM: major facilitator superfamily MFS_1; KEGG: sgl:SG0019 putative transport protein YP_001478569.1 KEGG: eca:ECA2249 hypothetical protein YP_001478570.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001478571.1 KEGG: eca:ECA2241 hypothetical protein YP_001478572.1 PFAM: protein of unknown function DUF172; KEGG: ypi:YpsIP31758_2237 prevent-host-death family protein YP_001478573.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aav:Aave_2184 GCN5-related N-acetyltransferase YP_001478574.1 KEGG: bte:BTH_II1440 hypothetical protein YP_001478575.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001478576.1 PFAM: extracellular solute-binding protein family 5; KEGG: ecs:ECs2091 putative hemin-binding lipoprotein YP_001478577.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1571 putative transport system permease protein YP_001478578.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ecs:ECs2089 putative transport protein YP_001478579.1 KEGG: ecj:JW1479 D-Ala-D-Ala transporter subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001478580.1 KEGG: ecs:ECs2087 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001478581.1 TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; KEGG: ypi:YpsIP31758_1025 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase YP_001478582.1 PFAM: major facilitator superfamily MFS_1; KEGG: bxe:Bxe_B0529 major facilitator superfamily (MFS) efflux pump YP_001478583.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rpe:RPE_2870 transcriptional regulator, LysR family YP_001478584.1 KEGG: kpn:KPN_04460 hypothetical protein YP_001478585.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: kpn:KPN_01815 cell elongation, e phase; peptidoglycan synthetase; penicillin-binding protein 2 YP_001478586.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: yen:YE1767 peptidoglycan synthetase YP_001478587.1 KEGG: pae:PA3497 hypothetical protein YP_001478588.1 KEGG: stm:STM1705 osmotically inducible lipoprotein YP_001478589.1 KEGG: sfv:SFV_0578 hypothetical protein YP_001478590.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0854 ABC transporter, ATP-binding protein YP_001478591.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0855 ABC transporter permease protein YP_001478592.1 PFAM: extracellular solute-binding protein family 3; KEGG: eca:ECA0856 ABC transporter, periplasmic binding protein YP_001478593.1 KEGG: ava:Ava_1266 xenobiotic compound monooxygenase, DszA family, A subunit YP_001478594.1 PFAM: MmgE/PrpD family protein; KEGG: eca:ECA3784 hypothetical protein YP_001478595.1 KEGG: bpe:BP0300 putative esterase YP_001478596.1 PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_0977 major facilitator superfamily MFS_1 YP_001478597.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_L_1189 hypothetical protein YP_001478598.1 KEGG: ent:Ent638_1138 hypothetical protein YP_001478599.1 KEGG: eca:ECA1405 putative exported protein YP_001478600.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_001478601.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KR domain protein; KEGG: ppu:PP_2986 oxidoreductase, putative YP_001478602.1 PFAM: regulatory protein TetR; KEGG: bur:Bcep18194_B1225 transcriptional regulator, TetR family YP_001478605.1 KEGG: rru:Rru_A1375 hypothetical protein YP_001478607.1 KEGG: rru:Rru_A1377 hypothetical protein YP_001478610.1 SMART: Hedgehog/intein hint domain protein; KEGG: plu:plu1731 hypothetical protein YP_001478612.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: csa:Csal_1436 helix-turn-helix protein, CopG YP_001478613.1 KEGG: maq:Maqu_2906 conserved hypothetical spermidine synthase YP_001478614.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: asa:ASA_3149 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase YP_001478615.1 PFAM: conserved hypothetical protein; KEGG: ecc:c3738 hypothetical protein YP_001478616.1 KEGG: eca:ECA2785 metalloprotease; PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; Peptidase M10 serralysin; SMART: peptidase metallopeptidase YP_001478617.1 PFAM: membrane attack complex component/perforin/complement C9; KEGG: cmi:CMM_2382 hypothetical protein, putative perforin YP_001478618.1 KEGG: ecv:APECO1_2952 arsenate reductase ArsC; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_001478619.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: ent:Ent638_4256 arsenical pump membrane protein YP_001478620.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001478621.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: PAS domain containing protein; AAA ATPase; KEGG: psp:PSPPH_2337 sigma-54 dependent transcriptional regulator YP_001478622.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: pst:PSPTO_3047 myo-inositol 2-dehydrogenase, putative YP_001478623.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: psp:PSPPH_2335 AP endonuclease, family 2 superfamily YP_001478624.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: kpn:KPN_00509 putative periplasmic binding protein YP_001478625.1 PFAM: amidinotransferase; KEGG: yen:YE2045 putative hydrolase YP_001478626.1 PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE2044 amino acid-binding periplasmic protein precursor YP_001478627.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2043 amino acid transport system permease protein YP_001478628.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cvi:CV_3087 histidine transport system membrane protein M YP_001478629.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: yen:YE2040 probable leucine-responsive regulatory protein YP_001478630.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: yen:YE2039 hypothetical protein YP_001478631.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: maq:Maqu_0009 ABC transporter related YP_001478632.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001478633.1 PFAM: regulatory protein LuxR; KEGG: gme:Gmet_2158 two component transcriptional regulator, LuxR family YP_001478635.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: bch:Bcen2424_1755 fimbrial biogenesis outer membrane usher protein YP_001478636.1 member of the periplasmic pilus chaperone family of proteins YP_001478637.1 PFAM: protein of unknown function DUF1120; KEGG: bch:Bcen2424_1753 protein of unknown function DUF1120 YP_001478638.1 PFAM: integrase family protein; KEGG: ecv:APECO1_1681 hypothetical protein YP_001478639.1 PFAM: aldehyde dehydrogenase; KEGG: pae:PA4022 probable aldehyde dehydrogenase YP_001478640.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: kpn:KPN_02992 putative helix-turn-helix, fis-type YP_001478641.1 PFAM: extracellular solute-binding protein family 3; KEGG: eca:ECA2156 ABC transporter, substrate binding protein YP_001478642.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: atc:AGR_C_2202 copper-transporting ATPase YP_001478643.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; KEGG: acb:A1S_1949 putative diguanylate cyclase/phosphodiesterase YP_001478644.1 PFAM: Pyrrolo-quinoline quinone; KEGG: atc:AGR_L_2936 probable quinate dehydrogenase YP_001478645.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: atu:Atu2171 hydrolase YP_001478646.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_03313 putative bacterial regulatory protein, LysR YP_001478647.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: eca:ECA2244 L-2,4-diaminobutyrate decarboxylase YP_001478648.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_001478649.1 KEGG: aha:AHA_3686 histidine kinase-response regulator hybrid protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001478651.1 TIGRFAM: high-affinity nickel-transporter; KEGG: plu:plu2170 putative high-affinity nickel-transport protein YP_001478652.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: yen:YE3600 hydrogenase maturation protein YP_001478653.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: kpn:KPN_02090 formate dehydrogenase H, selenopolypeptide subunit YP_001478654.1 involved in electron transport from formate to hydrogen YP_001478655.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_001478656.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: kpn:KPN_03055 processing of HycE (part of the FHL complex) YP_001478657.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ent:Ent638_3192 NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001478658.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_001478659.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: stm:STM2849 hydrogenase 3 large subunit YP_001478660.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: kpn:KPN_03059 hydrogenase 3, membrane subunit (part of FHL complex) YP_001478661.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: spt:SPA2709 NADH dehydrogenase subunit N YP_001478662.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stm:STM2852 hydrogenase-3 iron-sulfur subunit YP_001478663.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_001478664.1 plays a role in hydrogenase nickel cofactor insertion YP_001478665.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_001478666.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: yen:YE2796 putative hydrogenase isoenzymes formation protein YP_001478667.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: yen:YE3602 hydrogenase isoenzymes formation protein YP_001478668.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sec:SC2791 putative hydrogenase expression/formation protein YP_001478669.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons YP_001478670.1 KEGG: sgl:SGP2_0007 hypothetical protein YP_001478671.1 KEGG: pst:PSPTO_2895 hypothetical protein YP_001478672.1 KEGG: pfl:PFL_2568 sensory box transcriptional regulator, LuxR family; TIGRFAM: PAS sensor protein; PFAM: regulatory protein LuxR; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001478673.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: aor:AO090102000042 predicted iron-dependent peroxidase YP_001478674.1 KEGG: cvi:CV_2052 hypothetical protein YP_001478675.1 PFAM: protein of unknown function DUF336; KEGG: mpt:Mpe_A1588 hypothetical protein YP_001478676.1 KEGG: aau:AAur_1002 putative RNase H YP_001478677.1 PFAM: NUDIX hydrolase; KEGG: mms:mma_2565 MutT/NUDIX-family hydrolase YP_001478678.1 PFAM: FAD dependent oxidoreductase; KEGG: pen:PSEEN3588 oxidase YP_001478679.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001478680.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001478681.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rso:RSp0505 2-hydroxyacid dehydrogenase YP_001478682.1 KEGG: plu:plu3520 hypothetical protein YP_001478683.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: plu:plu3519 unnamed protein product; highly similar to outer membrane receptor protein YP_001478684.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0049 transcriptional regulator, LysR family YP_001478685.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_0048 major facilitator superfamily MFS_1 YP_001478686.1 KEGG: ent:Ent638_0047 conserved hypothetical signal peptide protein YP_001478687.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: stm:STM1609 TDT family, K+-tellurite ethidium and proflavin transport protein YP_001478688.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bpl:BURPS1106A_A0260 transcriptional regulator, LysR family YP_001478689.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: bxe:Bxe_B2110 NAD(P)H dehydrogenase (quinone) YP_001478690.1 PFAM: FAD linked oxidase domain protein; KEGG: ecv:APECO1_3760 putative FAD containing dehydrogenase YP_001478691.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ecs:ECs3630 putative oxidoreductase YP_001478692.1 PFAM: major facilitator superfamily MFS_1; KEGG: ecj:JW2746 predicted transporter YP_001478693.1 PFAM: carbohydrate kinase FGGY; KEGG: ecv:APECO1_3757 putative sugar kinase YgcE YP_001478694.1 PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: ecs:ECs3623 putative anti-terminator regulatory protein YP_001478695.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2501 putative LysR-family transcriptional regulator YP_001478696.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1874 transporter protein YP_001478697.1 PFAM: Formaldehyde-activating enzyme (Fae); KEGG: ypi:YpsIP31758_1542 hypothetical protein YP_001478698.1 PFAM: aldo/keto reductase; KEGG: ypi:YpsIP31758_1541 oxidoreductase, aldo/keto reductase family YP_001478699.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: yen:YE3793 succinate-semialdehyde dehydrogenase YP_001478700.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; KEGG: pfl:PFL_3482 transcriptional regulator, MarR family/acetyl transferase, GNAT family YP_001478701.1 PFAM: amino acid permease-associated region; KEGG: plu:plu3105 unnamed protein product; similar to D-serine/D-alanine/glycine transporter YP_001478702.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: kpn:KPN_01492 putative glutamic dehyrogenase-like protein YP_001478703.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro03779 long-chain-fatty-acid--CoA ligase YP_001478704.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: kpn:KPN_01321 putative intracellular protease/amidase YP_001478705.1 PFAM: protein of unknown function DUF1493 YP_001478706.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: yen:YE0445 probable outer membrane efflux lipoprotein YP_001478707.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE0444 multidrug efflux protein YP_001478708.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3586 efflux transporter, RND family, MFP subunit YP_001478709.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_0043 drug resistance transporter, EmrB/QacA subfamily YP_001478710.1 PFAM: regulatory protein TetR; KEGG: bxe:Bxe_B1778 transcriptional regulator, TetR family YP_001478711.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: pen:PSEEN4632 peptidylarginine deiminase, PPADH family YP_001478712.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_2369 transcriptional regulator, LysR family YP_001478713.1 KEGG: pap:PSPA7_4047 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001478714.1 KEGG: xcb:XC_2212 hypothetical protein YP_001478715.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aav:Aave_0714 GCN5-related N-acetyltransferase YP_001478716.1 PFAM: helix-turn-helix domain protein; KEGG: eca:ECA3650 putative DNA-binding protein YP_001478717.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA3651 hypothetical protein YP_001478718.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: shn:Shewana3_4234 transposase, IS605 OrfB family YP_001478719.1 PFAM: cytochrome c class I; KEGG: pae:PA1600 probable cytochrome c YP_001478720.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: pae:PA1601 probable aldehyde dehydrogenase YP_001478721.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: pau:PA14_43780 putative oxidoreductase YP_001478722.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: azo:azo0369 probable cysteine desulphurase YP_001478723.1 KEGG: mpt:Mpe_A0024 hypothetical protein YP_001478724.1 KEGG: mpt:Mpe_A0026 serine O-acetyltransferase YP_001478725.1 SMART: Rhodanese domain protein; KEGG: mpt:Mpe_A0027 hypothetical protein YP_001478726.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypp:YPDSF_1946 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_001478727.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yps:YPTB2567 putative 2-ketogluconate transporter, ACS family-MFS superfamily YP_001478728.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE1415 putative LacI-family regulatory protein YP_001478729.1 PFAM: glycoside hydrolase family 1; KEGG: yen:YE1417 6-phospho-beta-glucosidase YP_001478730.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: kpn:KPN_01948 putative oxidoreductase YP_001478731.1 KEGG: kpn:KPN_01949 intradiol ring-cleavage dioxygenase; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase YP_001478732.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: stm:STM1625 putative transcriptional regulator YP_001478733.1 KEGG: kpn:KPN_01543 putative 4-carboxymuconolactone decarboxylase; TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase YP_001478734.1 TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: kpn:KPN_01541 putative fumarate lyase YP_001478735.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001478736.1 TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_03917 putative permeases of the major facilitator superfamily YP_001478737.1 KEGG: kpn:KPN_01544 hypothetical protein YP_001478738.1 KEGG: kpn:KPN_04100 hypothetical protein YP_001478739.1 KEGG: kpn:KPN_04099 putative outer membrane protein YP_001478740.1 KEGG: kpn:KPN_01798 hypothetical protein YP_001478741.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_00382 general substrate transporter YP_001478742.1 PFAM: regulatory protein TetR; KEGG: ent:Ent638_0520 transcriptional regulator, TetR family YP_001478743.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: kpn:KPN_01537 putative transcriptional repressor (IclR family) YP_001478744.1 catalyzes the formation of pyruvate from serine YP_001478745.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: mes:Meso_0138 3-demethylubiquinone-9 3-methyltransferase YP_001478746.1 PFAM: protein of unknown function DUF1428; KEGG: ent:Ent638_0929 protein of unknown function DUF1428 YP_001478747.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pen:PSEEN2260 diguanylate cyclase (GGDEF) domain YP_001478748.1 KEGG: pdi:BDI_0439 putative glycosyltransferase YP_001478749.1 KEGG: ypi:YpsIP31758_0711 aerobactin siderophore biosynthesis protein IucD YP_001478750.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: pin:Ping_2381 alpha-D-1,4-glucosidase YP_001478751.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rso:RSc2140 probable sugar ATP-binding ABC transporter protein YP_001478752.1 PFAM: glycoside hydrolase family 4; KEGG: mag:amb2735 alpha-galactosidase/6-phospho-beta-glucosidase YP_001478753.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bms:BRA0306 sugar ABC transporter, permease protein YP_001478754.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_00203 ABC-type sugar transport system, permease components YP_001478755.1 PFAM: extracellular solute-binding protein family 1; KEGG: csa:Csal_0258 extracellular solute-binding protein, family 1 YP_001478756.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB0712 hypothetical transcriptional regulator YP_001478757.1 PFAM: MscS Mechanosensitive ion channel; KEGG: yen:YE0322 putative inner-membrane transport protein YP_001478758.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2048 ABC transporter related YP_001478759.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: nha:Nham_1450 cation diffusion facilitator family transporter YP_001478760.1 PFAM: CBS domain containing protein; MgtE integral membrane region; KEGG: kpn:KPN_03856 putative Mg/Co/Ni transporter MgtE YP_001478761.1 PFAM: transposase IS605 OrfB; KEGG: sfv:SFV_1675 putative virulence protein YP_001478762.1 KEGG: eca:ECA1942 putative periplasmic oligopeptide-binding protein YP_001478763.1 PFAM: extracellular solute-binding protein family 1; KEGG: yen:YE1241 iron(III)-binding periplasmic protein YP_001478764.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1240 iron(III)-transport system permease YP_001478765.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1348 iron(III) ABC transporter, ATP-binding protein YP_001478766.1 TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: vei:Veis_1261 translation elongation factor G YP_001478767.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA1517 hypothetical protein YP_001478768.1 PFAM: periplasmic binding protein; KEGG: prw:PsycPRwf_0745 periplasmic binding protein YP_001478769.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: eca:ECA1518 AraC-family transcriptional regulator YP_001478770.1 PFAM: aldehyde dehydrogenase; KEGG: atc:AGR_L_2660 hypothetical protein YP_001478771.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bur:Bcep18194_B3090 esterase/lipase/thioesterase YP_001478772.1 PFAM: alpha/beta hydrolase fold; KEGG: bur:Bcep18194_B3091 alpha/beta hydrolase YP_001478773.1 PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: pfl:PFL_3507 AP endonuclease family 2 protein YP_001478774.1 PFAM: regulatory protein TetR; KEGG: bur:Bcep18194_B3093 transcriptional regulator, TetR family YP_001478775.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: bur:Bcep18194_B0543 hypothetical protein YP_001478776.1 PFAM: K potassium transporter; KEGG: bra:BRADO1466 potassium transport system, low affinity (KUP family) YP_001478777.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bam:Bamb_3505 transcriptional regulator, LysR family YP_001478778.1 PFAM: inner-membrane translocator; KEGG: bxe:Bxe_A0822 ABC branched chain amino acid family transporter, inner membrane subunit YP_001478779.1 PFAM: inner-membrane translocator; KEGG: rso:RSc2439 probable amino-acid transmembrane ABC transporter protein YP_001478780.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rme:Rmet_2864 ABC transporter-related protein YP_001478781.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bte:BTH_I0788 branched-chain amino acid ABC transporter, ATP-binding protein YP_001478782.1 PFAM: Extracellular ligand-binding receptor; KEGG: bam:Bamb_3506 extracellular ligand-binding receptor YP_001478783.1 KEGG: bur:Bcep18194_B1949 hypothetical protein YP_001478784.1 KEGG: bxe:Bxe_A1427 amidase, hydantoinase/carbamoylase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001478785.1 PFAM: regulatory protein ArsR; KEGG: mms:mma_1896 transcriptional regulator, ArsR family YP_001478786.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mms:mma_1897 hypothetical protein YP_001478787.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: kpn:KPN_01510 putative Mg2+ and Co2+ transporters YP_001478788.1 PFAM: phosphate transporter; KEGG: pfo:Pfl_4319 phosphate transporter YP_001478789.1 PFAM: protein of unknown function DUF344; KEGG: bur:Bcep18194_B1834 protein of unknown function DUF344 YP_001478790.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bxe:Bxe_A1545 peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001478791.1 PFAM: luciferase family protein; KEGG: bch:Bcen2424_6567 luciferase family protein YP_001478792.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: aav:Aave_0017 transcriptional regulator, GntR family YP_001478794.1 PFAM: glutamine amidotransferase class-I; KEGG: cvi:CV_3746 glutamine amidotransferase YP_001478795.1 TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: kpn:KPN_02766 pyridoxine kinase YP_001478796.1 PFAM: type IV pilus assembly PilZ; YcgR family protein; KEGG: ent:Ent638_2358 YcgR family protein YP_001478797.1 PFAM: N-formylglutamate amidohydrolase; KEGG: yen:YE2073 hypothetical protein YP_001478798.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: eca:ECA4119 putative acyltransferase YP_001478799.1 KEGG: pac:PPA1958 hypothetical protein YP_001478800.1 PFAM: extracellular solute-binding protein family 1; KEGG: cpr:CPR_0476 ABC transporter, substrate-binding protein YP_001478801.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bcz:BCZK1635 sugar ABC transporter, permease YP_001478802.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bcz:BCZK1636 sugar ABC transporter, permease YP_001478803.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: amt:Amet_0894 ABC transporter related YP_001478804.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: dre:556929 zgc:154075 YP_001478805.1 PFAM: ROK family protein; KEGG: pin:Ping_1332 ROK family protein YP_001478806.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: plu:plu0832 putative aga operon transcriptional repressor YP_001478807.1 TIGRFAM: Sugar isomerase AgaS; PFAM: sugar isomerase (SIS); KEGG: plu:plu0834 putative tagatose-6-phosphate ketose/aldose isomerase YP_001478808.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001478810.1 KEGG: ypi:YpsIP31758_1834 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding YP_001478811.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001478812.1 with UspC and UspD is involved in resistance to UV irradiation YP_001478813.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001478814.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001478815.1 PFAM: protein of unknown function DUF1471; KEGG: ypi:YpsIP31758_1829 hypothetical protein YP_001478816.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_1828 putative arginine/ornithine antiporter ArcD YP_001478817.1 KEGG: ypi:YpsIP31758_1827 hypothetical protein YP_001478818.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA2018 short chain dehydrogenase YP_001478819.1 response regulator in two-component regulatory system with RstB YP_001478820.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1825 sensor protein RstB YP_001478821.1 PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: yen:YE2085 putative carboxypeptidase YP_001478822.1 KEGG: ecj:JW5826 acid shock-inducible periplasmic protein YP_001478823.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: yen:YE2087 possible protease YP_001478824.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001478825.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001478826.1 PFAM: conserved hypothetical protein; KEGG: yen:YE2095 hypothetical protein YP_001478827.1 KEGG: kpn:KPN_01452 hypothetical protein YP_001478828.1 KEGG: yen:YE2097 hypothetical protein YP_001478829.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_1808 fermentative lactate dehydrogenase YP_001478830.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: ypi:YpsIP31758_1807 heat shock protein HslJ YP_001478831.1 KEGG: yen:YE2099 putative lipoprotein YP_001478832.1 PFAM: small multidrug resistance protein; KEGG: yen:YE2101 quaternary ammonium compound-resistance protein YP_001478833.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: yen:YE2102 putative pyruvate-flavodoxin oxidoreductase YP_001478834.1 PFAM: peptidase S24 and S26 domain protein; KEGG: stm:STM1998 error-prone repair: SOS-response transcriptional repressors (LexA homologs, RecA-mediated autopeptidases) YP_001478835.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: ecc:c1632 umuC protein YP_001478836.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001478837.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: psa:PST_3709 lactoylglutathione lyase YP_001478838.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: yen:YE2107 CorA-like Mg2+ transporter protein YP_001478839.1 KEGG: aav:Aave_3037 hypothetical protein YP_001478840.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2110 putative periplasmic murein peptide-binding protein YP_001478842.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pap:PSPA7_4415 alcohol dehydrogenase, zinc-binding YP_001478843.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: yen:YE2111 hypothetical protein YP_001478844.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: yps:YPTB2260 putative mandelate racemase / muconate lactonizing protein YP_001478845.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001478846.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001478847.1 PFAM: conserved hypothetical protein; KEGG: yen:YE2117 hypothetical protein YP_001478848.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: yen:YE2118 hypothetical protein YP_001478849.1 KEGG: gvi:gll4242 unknown protein YP_001478850.1 TIGRFAM: shock protein PspD; KEGG: ent:Ent638_2166 phage shock protein D YP_001478851.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001478852.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001478853.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001478854.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001478855.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: csa:Csal_0192 cobalamin synthesis protein, P47K YP_001478856.1 KEGG: pst:PSPTO_2579 carbonic anhydrase-related protein YP_001478857.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001478858.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2125 peptide transport periplasmic protein precursor YP_001478859.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2126 peptide transport system permease protein YP_001478860.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE2127 peptide transport system permease protein YP_001478861.1 KEGG: yen:YE2128 peptide transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001478862.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1780 peptide ABC transporter, ATP-binding protein SapF YP_001478863.1 TIGRFAM: uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: ypi:YpsIP31758_1779 hypothetical protein YP_001478864.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2132 LysR-family transcriptional regulatory protein YP_001478865.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001478866.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yen:YE1983 putative oxidoreductase YP_001478867.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001478868.1 PFAM: carbon starvation protein CstA; KEGG: yen:YE1981 putative carbon starvation protein A YP_001478869.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001478870.1 KEGG: yen:YE0645 putative pyruvate formate-lyase 3 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein YP_001478871.1 KEGG: yen:YE0646 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001478872.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sec:SC1699 putative regulatory protein, DeoR family YP_001478873.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001478874.1 KEGG: ypi:YpsIP31758_1911 putative lipoprotein YP_001478875.1 involved in start site selection during the initiation of translation YP_001478876.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001478877.1 PFAM: protein of unknown function DUF1471; KEGG: kpn:KPN_00833 hypothetical protein YP_001478878.1 KEGG: ypi:YpsIP31758_1914 hypothetical protein YP_001478879.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: yen:YE1968 hypothetical protein YP_001478880.1 PFAM: protein of unknown function DUF1049; KEGG: ypm:YP_2023 hypothetical protein YP_001478881.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: eca:ECA1944 phosphatidylglycerophosphatase B YP_001478882.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001478883.1 Catalyzes the conversion of citrate to isocitrate YP_001478884.1 KEGG: bch:Bcen2424_5419 hypothetical protein YP_001478885.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001478886.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001478887.1 KEGG: yps:YPTB2139 hypothetical protein YP_001478888.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001478889.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypm:YP_2012 short chain dehydrogenase YP_001478890.1 KEGG: ypi:YpsIP31758_1927 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001478891.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001478892.1 KEGG: nfa:nfa52190 putative dioxygenase YP_001478893.1 KEGG: cps:CPS_1624 hypothetical protein YP_001478894.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: ypi:YpsIP31758_1929 SUA5/YciO/YrdC/YwlC family protein YP_001478895.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypi:YpsIP31758_1930 PHP domain protein YP_001478896.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001478897.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001478898.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001478899.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001478900.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001478901.1 KEGG: ypi:YpsIP31758_1937 tryptophan synthase, alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase alpha chain YP_001478902.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ypi:YpsIP31758_1939 putative phospholipid-binding domain protein YP_001478903.1 receptor for colicin S4 YP_001478904.1 PFAM: protein of unknown function UPF0259; KEGG: yen:YE2218 hypothetical protein YP_001478905.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: ypi:YpsIP31758_1943 sulfate permease family protein YP_001478906.1 Involved in cell division; probably involved in intracellular septation YP_001478907.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_001478908.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rso:RSc1014 probable transcriptional regulatory DNA-binding repressor transcription regulator protein YP_001478909.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: slo:Shew_3859 inosine/uridine-preferring nucleoside hydrolase YP_001478910.1 PFAM: major facilitator superfamily MFS_1; KEGG: spc:Sputcn32_1658 major facilitator superfamily MFS_1 YP_001478911.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001478912.1 PFAM: protein of unknown function DUF208; KEGG: sbo:SBO_1709 hypothetical protein YP_001478913.1 PFAM: YCII-related; KEGG: ent:Ent638_2288 YCII-related YP_001478915.1 PFAM: regulatory protein TetR; KEGG: pau:PA14_47610 putative transcriptional regulator YP_001478916.1 PFAM: major facilitator superfamily MFS_1; KEGG: pau:PA14_47640 putative major facilitator superfamily (MFS) transporter YP_001478917.1 PFAM: Ferritin Dps family protein; KEGG: vco:VC0395_A2381 DPS family protein YP_001478918.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001478919.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001478920.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: bbt:BBta_2220 glycerol-3-phosphate regulon repressor, transcriptional regulator protein, DeoR family YP_001478921.1 PFAM: carbohydrate kinase FGGY; KEGG: pae:PA1487 probable carbohydrate kinase YP_001478922.1 PFAM: Ethanolamine utilisation protein EutH; KEGG: pae:PA1491 probable transporter YP_001478923.1 KEGG: pae:PA1492 hypothetical protein YP_001478924.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vei:Veis_1679 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001478925.1 PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: pfl:PFL_0501 oxidoreductase, FAD-binding YP_001478926.1 KEGG: yen:YE2229 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001478927.1 KEGG: yen:YE2230 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001478928.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1822 OppC YP_001478929.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2323 oligopeptide transport system permease protein YP_001478930.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2233 periplasmic oligopeptide-binding protein precursor YP_001478931.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE2234 periplasmic oligopeptide-binding protein precursor YP_001478932.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: yen:YE2237 hypothetical protein YP_001478933.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: yen:YE2238 aldehyde-alcohol dehydrogenase YP_001478934.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001478935.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: ypi:YpsIP31758_1966 DNA-binding protein H-NS YP_001478936.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: kpn:KPN_02492 uridine diphosphate galacturonate 4-epimerase YP_001478937.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sgl:SG1368 putative UDP-glucose dehydrogenase YP_001478938.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001478939.1 PFAM: response regulator receiver; KEGG: yen:YE2243 probable response regulator YP_001478940.1 PFAM: Patatin; KEGG: yen:YE2244 hypothetical protein YP_001478941.1 PFAM: SEC-C motif domain protein; KEGG: yen:YE2246 hypothetical protein YP_001478942.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001478943.1 PFAM: conserved hypothetical protein; KEGG: psa:PST_1098 hypothetical protein YP_001478944.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001478945.1 PFAM: NUDIX hydrolase; KEGG: yen:YE2255 putative pyrophosphohydrolase YP_001478946.1 PFAM: protein of unknown function DUF1496; KEGG: yen:YE2256 hypothetical protein YP_001478947.1 decatenates replicating daughter chromosomes YP_001478948.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001478949.1 KEGG: yen:YE2258 selenide, water dikinase; TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001478950.1 PFAM: nitroreductase; KEGG: ypi:YpsIP31758_1981 nitroreductase family protein YP_001478951.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001478952.1 converts asparagine to aspartate and ammonia YP_001478953.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001478954.1 PFAM: glycoside hydrolase family 18; SMART: chitinase II; KEGG: kpn:KPN_01201 putative chitinase II YP_001478955.1 PFAM: protein of unknown function DUF1315; KEGG: yen:YE2263 hypothetical protein YP_001478956.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001478957.1 KEGG: ypi:YpsIP31758_1987 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001478958.1 PFAM: Aldose 1-epimerase; KEGG: yps:YPTB2082 hypothetical protein YP_001478959.1 PFAM: MltA-interacting MipA family protein; KEGG: ypi:YpsIP31758_1990 MltA-interacting protein YP_001478960.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: yen:YE2272 hypothetical protein YP_001478961.1 PFAM: protein of unknown function DUF444; KEGG: yen:YE2273 hypothetical protein YP_001478962.1 KEGG: bur:Bcep18194_A4761 hypothetical protein YP_001478963.1 PFAM: protein of unknown function UPF0057; KEGG: eca:ECA2844 hypothetical protein YP_001478964.1 KEGG: eca:ECA1771 hypothetical protein YP_001478965.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yen:YE0323 ferrioxamine receptor precursor YP_001478968.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1552 ABC transporter ATP-binding protein YP_001478969.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA1551 ABC transporter ATP binding protein YP_001478970.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1549 putative ABC transporter substrate-binding protein YP_001478971.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA1548 putative transport system membrane protein YP_001478972.1 KEGG: sec:SC0331 endodeoxyribonuclease YP_001478973.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1996 drug resistance transporter, Bcr/CflA family YP_001478974.1 KEGG: ent:Ent638_2362 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001478975.1 catalyzes the oxidative deamination of D-amino acids YP_001478976.1 PFAM: SpoVR family protein; KEGG: ypi:YpsIP31758_1998 SpoVR family protein YP_001478977.1 Multifunctional regulator of fatty acid metabolism YP_001478978.1 involved in regulation of intracellular pH under alkaline conditions YP_001478979.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001478980.1 PFAM: protein of unknown function UPF0153; KEGG: yen:YE2365 hypothetical protein YP_001478981.1 KEGG: ent:Ent638_1759 protein of unknown function DUF883, ElaB YP_001478982.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: yen:YE2366 putative fumarylacetoacetate hydrolase family protein YP_001478983.1 TIGRFAM: lytic murein transglycosylase; KEGG: yen:YE2367 putative lipoprotein YP_001478984.1 PFAM: protein of unknown function DUF709; KEGG: ecv:APECO1_292 hypothetical protein YP_001478985.1 blocks the formation of polar Z-ring septums YP_001478986.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001478987.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001478988.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: ypp:YPDSF_1046 ribonuclease D YP_001478989.1 Activates fatty acids by binding to coenzyme A YP_001478990.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: yen:YE2376 putative lipoprotein YP_001478991.1 PFAM: peptidase M22 glycoprotease; KEGG: ypi:YpsIP31758_2016 peptidase family M22, nonpeptidase-like protein YP_001478992.1 SMART: helicase c2; DEAD-like helicases; KEGG: ypi:YpsIP31758_2017 hypothetical protein YP_001478993.1 PFAM: Endoribonuclease L-PSP; KEGG: plu:plu2128 hypothetical protein YP_001478994.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001478995.1 PFAM: small multidrug resistance protein; KEGG: yen:YE2381 putative inner membrane protein YP_001478996.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001478997.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001478998.1 Represses the expression of the zwf, eda, glp and gap YP_001478999.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001479000.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001479001.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; Opacity-associated protein A domain protein; KEGG: ypi:YpsIP31758_2026 peptidase, M23 family YP_001479002.1 involved in transport of zinc(II) with ZnuA and C YP_001479003.1 involved in transport of zinc(II) with ZnuA and C YP_001479004.1 involved in transport of zinc(II) with ZnuA and C YP_001479005.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001479006.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001479007.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001479008.1 PFAM: protein of unknown function DUF28; KEGG: eca:ECA2494 hypothetical protein YP_001479009.1 PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_2034 putative dATP pyrophosphohydrolase YP_001479010.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001479011.1 TIGRFAM: putative regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; KEGG: aeh:Mlg_0229 putative regulatory protein, FmdB family YP_001479012.1 PFAM: isochorismatase hydrolase; KEGG: yen:YE2398 putative isochorismatase YP_001479013.1 PFAM: protein of unknown function DUF72; KEGG: yen:YE2399 hypothetical protein YP_001479014.1 KEGG: yen:YE2400 hypothetical protein YP_001479015.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ypi:YpsIP31758_2038 putative methyltransferase YP_001479016.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; KEGG: yen:YE2402 hypothetical protein YP_001479017.1 PFAM: CutC family protein; KEGG: yen:YE2403 putative copper homeostasis protein YP_001479018.1 PFAM: aminotransferase class I and II; KEGG: aha:AHA_3110 putative aminotransferase B YP_001479019.1 PFAM: protein of unknown function DUF991; KEGG: ecv:APECO1_925 hypothetical protein YP_001479020.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001479021.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: yen:YE2409 hypothetical protein YP_001479022.1 PFAM: oxidoreductase domain protein; KEGG: yps:YPTB2025 putative oxidoreductase YP_001479023.1 PFAM: protein of unknown function DUF480; KEGG: stm:STM1168 putative cytoplasmic protein YP_001479024.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE2412 ribosomal-protein-alanine acetyltransferase YP_001479025.1 Confers resistance to norfloxacin and enoxacin YP_001479027.1 cofactor involved in the reduction of disulfides YP_001479028.1 PFAM: ABC-1 domain protein; KEGG: sfr:Sfri_1807 ABC-1 domain protein YP_001479029.1 PFAM: protein of unknown function DUF1439; KEGG: yen:YE2419 putative lipoprotein YP_001479030.1 secreted protein; unknown function YP_001479031.1 PFAM: protein of unknown function DUF437; KEGG: yen:YE1787 hypothetical protein YP_001479032.1 PFAM: YebG family protein; KEGG: yen:YE1786 hypothetical protein YP_001479033.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001479034.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001479035.1 PFAM: protein of unknown function UPF0181; KEGG: ypi:YpsIP31758_2352 hypothetical protein YP_001479036.1 PFAM: glycosyl transferase family 2; KEGG: ecp:ECP_3716 putative glycosyl transferase YibD YP_001479037.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: yps:YPTB1649 para-aminobenzoate synthase component I YP_001479038.1 PFAM: NUDIX hydrolase; KEGG: yen:YE1780 MutT-family protein YP_001479039.1 KEGG: ypi:YpsIP31758_2355 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001479040.1 PFAM: EAL domain protein; KEGG: ent:Ent638_2384 diguanylate phosphodiesterase YP_001479041.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: ypi:YpsIP31758_2367 membrane protein TerC family/CBS domain protein YP_001479042.1 KEGG: yps:YPTB1634 PTS system, mannose-specific IIAB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component; PTS system sorbose subfamily IIB component YP_001479043.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: ypi:YpsIP31758_2369 PTS system, mannose/fructose/sorbose family, IIC component YP_001479044.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001479045.1 PFAM: protein of unknown function DUF986; KEGG: ypi:YpsIP31758_2371 hypothetical protein YP_001479046.1 PFAM: protein of unknown function DUF204; KEGG: yen:YE1772 hypothetical protein YP_001479047.1 PFAM: major facilitator superfamily MFS_1; KEGG: vei:Veis_4582 drug resistance transporter, EmrB/QacA subfamily YP_001479048.1 SMART: regulatory protein ArsR; KEGG: ccr:CC_3070 transcriptional regulator, ArsR family YP_001479049.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001479050.1 PFAM: protein of unknown function DUF152; KEGG: ypk:y2562 hypothetical protein YP_001479051.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yps:YPTB1624 cold shock protein YP_001479052.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2754 metallo-beta-lactamase family protein YP_001479054.1 PFAM: amino acid permease-associated region; KEGG: yen:YE1761 aromatic amino acid transport protein YP_001479055.1 KEGG: ypi:YpsIP31758_2382 hypothetical protein YP_001479056.1 KEGG: ypi:YpsIP31758_2383 hypothetical protein YP_001479057.1 KEGG: yps:YPTB1618 hypothetical protein YP_001479058.1 KEGG: plu:plu2786 hypothetical protein YP_001479059.1 KEGG: ypi:YpsIP31758_2385 hypothetical protein YP_001479060.1 KEGG: ypi:YpsIP31758_2386 hypothetical protein YP_001479061.1 KEGG: kpn:KPN_01028 hypothetical protein YP_001479062.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1753 AraC-family transcriptional regulatory protein YP_001479063.1 PFAM: protein of unknown function DUF1304; KEGG: kpn:KPN_01507 hypothetical protein YP_001479064.1 PFAM: Pirin domain protein; KEGG: csa:Csal_1778 pirin-like protein YP_001479065.1 PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: stm:STM2795 hypothetical protein YP_001479066.1 PFAM: protein of unknown function DUF1482; KEGG: kpn:KPN_02353 hypothetical protein YP_001479068.1 PFAM: porin Gram-negative type; KEGG: yen:YE2463 outer membrane porin protein YP_001479069.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001479070.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001479071.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001479072.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: yen:YE2468 arginine N-succinyltransferase YP_001479073.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001479074.1 PFAM: extracellular solute-binding protein family 1; KEGG: vvy:VVA0125 ABC-type sugar transport system, periplasmic component YP_001479075.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vvy:VVA0126 ABC-type sugar transport system, permease component YP_001479076.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vvy:VVA0127 ABC-type sugar transport system, permease component YP_001479077.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: gbe:GbCGDNIH1_2202 cytosol aminopeptidase YP_001479078.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_0607 ABC transporter related YP_001479079.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: smd:Smed_4293 periplasmic binding protein/LacI transcriptional regulator YP_001479080.1 PFAM: peptidase T2 asparaginase 2; KEGG: ftn:FTN_0588 asparaginase YP_001479081.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: psp:PSPPH_3647 lipase YP_001479082.1 KEGG: kpn:KPN_02023 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001479083.1 KEGG: kpn:KPN_02022 putative ABC transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001479084.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_02021 oligopeptide ABC transporter, permease protein YP_001479085.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_02020 oligopeptide ABC transporter, permease YP_001479086.1 PFAM: extracellular solute-binding protein family 5; KEGG: kpn:KPN_02019 putative oligopeptide ABC transporter, oligopeptide-binding protein YP_001479087.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE2470 putative GntR-family regulatory protein YP_001479088.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: yen:YE2471 putative cytochrome oxidase subunit YP_001479089.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: yen:YE2472 putative cytochrome oxidase subunit YP_001479090.1 KEGG: pfl:PFL_5362 hypothetical protein YP_001479091.1 PFAM: fatty acid desaturase; KEGG: eca:ECA0116 putative fatty acid desaturase YP_001479092.1 PFAM: fatty acid desaturase; KEGG: eca:ECA0115 putative fatty acid desaturase YP_001479093.1 PFAM: fatty acid hydroxylase; KEGG: eca:ECA0114 hypothetical protein YP_001479094.1 KEGG: eca:ECA0113 hypothetical protein YP_001479095.1 TIGRFAM: putative adenylate-forming enzyme; KEGG: ypi:YpsIP31758_2104 hypothetical protein YP_001479096.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2106 metallo-beta-lactamase family protein YP_001479097.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2107 NAD-dependent epimerase/dehydratase family protein YP_001479098.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: yps:YPTB1971 putative 3-oxoacyl-(acyl-carrier-protein) synthase III YP_001479100.1 PFAM: integrase family protein; KEGG: plu:plu0419 recombinase, type 1 fimbriae regulatory protein YP_001479101.1 PFAM: Fimbrial protein; KEGG: shm:Shewmr7_3393 fimbrial protein YP_001479102.1 PFAM: pili assembly chaperone; KEGG: sec:SC0176 putative fimbrial chaparone YP_001479103.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: kpn:KPN_00277 putative fimbrial usher YP_001479104.1 PFAM: Fimbrial protein; KEGG: ent:Ent638_1072 fimbrial protein YP_001479105.1 PFAM: Fimbrial protein; KEGG: ent:Ent638_1068 fimbrial protein YP_001479106.1 PFAM: Fimbrial protein; KEGG: kpn:KPN_03292 fimbrial morphology YP_001479107.1 PFAM: Fimbrial protein; KEGG: shm:Shewmr7_3393 fimbrial protein YP_001479108.1 PFAM: regulatory protein LuxR; KEGG: aha:AHA_1023 DNA-binding response regulator, LuxR family YP_001479109.1 KEGG: kpn:KPN_02211 nitrate reductase 1, cytochrome b(NR), gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_001479110.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: eca:ECA2033 respiratory nitrate reductase 1 delta chain YP_001479111.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: eca:ECA2032 respiratory nitrate reductase 1 beta chain YP_001479112.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain YP_001479114.1 PFAM: glycosyl transferase family 2; KEGG: pha:PSHAa1789 glycosyl transferase, 2 YP_001479115.1 PFAM: glycosyl transferase family 2; KEGG: bsu:BG11868 similar to capsular polysaccharide biosynthesis YP_001479116.1 PFAM: Carbohydrate-binding CenC domain protein; KEGG: ehi:10.t00010 hypothetical protein Pfam: CBM_4_9 YP_001479117.1 PFAM: glycosyl transferase family 2; KEGG: ecs:ECs2845 putative glycosyl transferase YP_001479118.1 PFAM: glycosyl transferase group 1; KEGG: gox:GOX0630 lipopolysaccharide core biosynthesis protein WbcM YP_001479119.1 PFAM: glycosyl transferase family 2; KEGG: sgl:SG0982 hypothetical protein YP_001479120.1 KEGG: sgl:SG1244 hypothetical protein YP_001479121.1 PFAM: polysaccharide biosynthesis protein; KEGG: ana:all4430 probable polysaccharide biosynthesis protein YP_001479122.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA1419 tyrosine-protein kinase YP_001479123.1 PFAM: polysaccharide export protein; KEGG: eca:ECA1417 putative polysaccharide export protein YP_001479124.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: eca:ECA1416 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_001479125.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tde:TDE1439 epimerase/dehydratase, putative YP_001479126.1 PFAM: transcriptional regulator domain protein; KEGG: vvy:VVA0492 hypothetical protein YP_001479127.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: spt:SPA1108 nitrite extrusion protein (nitrite facilitator) YP_001479128.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA2029 nitrate/nitrite sensor kinase YP_001479129.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_001479130.1 KEGG: ent:Ent638_2319 putative invasin YP_001479131.1 PFAM: peptidase A24A prepilin type IV; KEGG: yen:YE3574 type 4 prepilin-like proteins leader peptide processing enzyme YP_001479132.1 PFAM: PEBP family protein; KEGG: reu:Reut_B3733 YbhB and YbcL YP_001479133.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA2989 uroporphyrin-III C-methyltransferase YP_001479134.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA2990 nitrate reductase YP_001479135.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; Rieske [2Fe-2S] domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit YP_001479136.1 KEGG: eca:ECA2992 nitrate transport protein; TIGRFAM: nitrate ABC transporter, ATPase subunits C and D; PFAM: ABC transporter related; SMART: AAA ATPase YP_001479137.1 TIGRFAM: nitrate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA2993 nitrate transporter permease component YP_001479138.1 KEGG: eca:ECA2994 nitrate-binding proteint YP_001479139.1 PFAM: ANTAR domain protein; Nitrate and nitrite sensing domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator YP_001479140.1 PFAM: extracellular solute-binding protein family 5; KEGG: psp:PSPPH_2742 ABC transporter, periplasmic oligopeptide-binding protein YP_001479141.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_2060 ABC transporter related YP_001479142.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mmw:Mmwyl1_2059 ABC transporter related YP_001479143.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2058 binding-protein-dependent transport systems inner membrane component YP_001479144.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mmw:Mmwyl1_2057 binding-protein-dependent transport systems inner membrane component YP_001479145.1 PFAM: extracellular solute-binding protein family 5; KEGG: mmw:Mmwyl1_2056 extracellular solute-binding protein family 5 YP_001479146.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE2474 putative LysR-family transcriptional regulatory protein YP_001479147.1 PFAM: ChaC family protein; AIG2 family protein; KEGG: ecs:ECs1723 cation transport regulator YP_001479148.1 PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: yen:YE2476 hypothetical protein YP_001479149.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ypi:YpsIP31758_2124 calcium/proton antiporter YP_001479150.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: kpn:KPN_02997 hypothetical protein YP_001479151.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: dsy:DSY2332 putative anaerobic DMSO reductase chain A precursor YP_001479152.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dsy:DSY2331 putative anaerobic DMSO reductase chain B iron-sulfur subunit YP_001479153.1 KEGG: dsy:DSY2330 putative anaerobic DMSO reductase chain C anchor subunit YP_001479154.1 PFAM: PhoH family protein; KEGG: ypi:YpsIP31758_2125 putative PhoH protein YP_001479155.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ent:Ent638_2099 TonB-dependent siderophore receptor YP_001479156.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: yps:YPTB1727 putative iron-dependent peroxidase YP_001479157.1 KEGG: yen:YE1939 hypothetical protein YP_001479158.1 PFAM: iron permease FTR1; KEGG: ypp:YPDSF_1271 membrane protein YP_001479159.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: yen:YE1934 proline permease YP_001479160.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001479161.1 PFAM: YcfA family protein; KEGG: ypn:YPN_2306 hypothetical protein YP_001479162.1 PFAM: protein of unknown function UPF0150; KEGG: ypi:YpsIP31758_2305 hypothetical protein YP_001479163.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2514 putative amino-acid ABC transporter (ATP-binding protein) YP_001479164.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2273 amino acid ABC transporter, permease protein YP_001479165.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: yen:YE2516 putative cystine-binding periplasmic protein YP_001479166.1 catalyzes the formation of pyruvate from D-cysteine YP_001479167.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001479168.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001479169.1 PFAM: flagellin domain protein; KEGG: stt:t0918 flagellin YP_001479170.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: yen:YE2524 flagellar hook-associated protein 2 YP_001479171.1 flagellin specific chaperone YP_001479172.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001479173.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE2527 putative AraC-family transcriptional regulatory protein YP_001479175.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: eca:ECA1727 flagellar hook-basal body complex protein YP_001479176.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001479177.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001479178.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001479179.1 involved in type III protein export during flagellum assembly YP_001479180.1 rod/hook and filament chaperone YP_001479181.1 PFAM: flagellar hook-length control protein; KEGG: ypi:YpsIP31758_2295 flagellar hook-length control protein YP_001479182.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001479183.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001479184.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001479185.1 PFAM: flagellar biosynthesis protein FliO; KEGG: ypi:YpsIP31758_2301 flagellar protein FliO YP_001479186.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001479187.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001479188.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001479189.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: yen:YE2550 flagellar hook-associated protein 3 YP_001479190.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001479191.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001479192.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001479193.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001479194.1 makes up the distal portion of the flagellar basal body rod YP_001479195.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Yersinia contains two copies of this and other flagella genes YP_001479196.1 the hook connects flagellar basal body to the flagellar filament YP_001479197.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001479198.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001479199.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001479200.1 PFAM: SAF domain protein; KEGG: yen:YE2561 flagella basal body P-ring formation protein FlgA YP_001479201.1 regulates the flagellar specific sigma28 transcription factor YP_001479202.1 PFAM: FlgN family protein; KEGG: yen:YE2563 flagella synthesis protein FlgN YP_001479203.1 KEGG: swi:Swit_0156 transcriptional regulator-like protein YP_001479204.1 PFAM: flagellar FlhE family protein; KEGG: ypi:YpsIP31758_2332 flagellar protein FlhE YP_001479205.1 membrane protein involved in the flagellar export apparatus YP_001479206.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Yersinia has 2 copies of flhB; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella YP_001479207.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001479208.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001479209.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001479210.1 methylates the MCP YP_001479211.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE2573 methyl-accepting chemotaxis protein YP_001479212.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yen:YE2575 methyl-accepting chemotaxis protein YP_001479213.1 PFAM: CheW domain protein; KEGG: ypi:YpsIP31758_1639 chemotaxis protein CheW YP_001479214.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001479215.1 PFAM: OmpA/MotB domain protein; KEGG: yen:YE2578 chemotaxis MotB protein YP_001479216.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001479217.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001479218.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001479219.1 PFAM: Haemolysin expression modulating family protein; KEGG: ecp:ECP_1570 hypothetical protein YdgT YP_001479220.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001479221.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: yen:YE2584 putative oxidoreductase YP_001479222.1 KEGG: rso:RSp0259 probable pyrrolidone-carboxylate peptidase protein; TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15 pyroglutamyl peptidase I YP_001479223.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO6255 putative transcriptional regulatory protein, LysR-family YP_001479226.1 KEGG: bpa:BPP0727 putative lipoprotein YP_001479227.1 PFAM: protein of unknown function DUF876; KEGG: bbr:BB0814 hypothetical protein YP_001479228.1 PFAM: OmpA/MotB domain protein; KEGG: bbr:BB0815 hypothetical protein YP_001479229.1 PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: bbr:BB0816 hypothetical protein YP_001479230.1 KEGG: bbr:BB0817 hypothetical protein YP_001479231.1 PFAM: ImpA domain protein; KEGG: bbr:BB0799 hypothetical protein YP_001479232.1 PFAM: conserved hypothetical protein; KEGG: azo:azo3895 putative cytoplasmic protein,SciH YP_001479233.1 PFAM: protein of unknown function DUF877; KEGG: bbr:BB0801 hypothetical protein YP_001479234.1 PFAM: protein of unknown function DUF796; KEGG: aav:Aave_1465 protein of unknown function DUF796 YP_001479235.1 PFAM: Forkhead-associated protein; KEGG: azo:azo3884 hypothetical regulatory protein YP_001479236.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: aav:Aave_1469 protein serine/threonine phosphatase YP_001479238.1 PFAM: virulence protein SciE type; KEGG: bbr:BB0803 hypothetical protein YP_001479239.1 PFAM: GPW/gp25 family protein; KEGG: bbr:BB0804 hypothetical protein YP_001479240.1 PFAM: protein of unknown function DUF879; KEGG: bbr:BB0805 hypothetical protein YP_001479241.1 PFAM: protein of unknown function DUF1305; KEGG: bbr:BB0807 hypothetical protein YP_001479242.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: pmy:Pmen_2331 ATPase AAA-2 domain protein YP_001479243.1 SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: azo:azo3888 putative serine/threonine kinase YP_001479244.1 PFAM: Rhs element Vgr protein; KEGG: bbr:BB0793 hypothetical protein YP_001479245.1 PFAM: Domain of unknown function DUF1795; KEGG: rso:RSc3427 hypothetical protein YP_001479246.1 PFAM: PAAR repeat-containing protein; KEGG: rso:RSc3426 probable transmembrane protein YP_001479247.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: ppf:Pput_1073 ADP-ribosyl-(dinitrogen reductase) hydrolase YP_001479248.1 PFAM: protein of unknown function DUF796; KEGG: bpa:BPP0716 hypothetical protein YP_001479250.1 PFAM: transcription activator effector binding; KEGG: yen:YE2070 DNA gyrase inhibitory protein YP_001479251.1 PFAM: tryptophan 23-dioxygenase; KEGG: mxa:MXAN_7400 putative tryptophan 2,3-dioxygenase YP_001479252.1 PFAM: MaoC domain protein dehydratase; KEGG: stp:Strop_0462 MaoC domain protein dehydratase YP_001479253.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: stp:Strop_0460 ornithine cyclodeaminase/mu-crystallin YP_001479254.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001479255.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001479256.1 PFAM: HpcH/HpaI aldolase; KEGG: stp:Strop_0459 HpcH/HpaI aldolase YP_001479257.1 PFAM: aminotransferase class I and II; KEGG: stp:Strop_0458 aminotransferase, class I and II YP_001479258.1 KEGG: stp:Strop_0457 transcription factor jumonji, JmjC domain protein YP_001479259.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_2693 major facilitator superfamily MFS_1 YP_001479260.1 PFAM: creatinase; peptidase M24; KEGG: sfr:Sfri_3046 peptidase M24 YP_001479261.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001479262.1 detoxifies nitric oxide using NADH YP_001479263.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001479264.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: psb:Psyr_2034 outer membrane autotransporter barrel YP_001479265.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: kpn:KPN_01537 putative transcriptional repressor (IclR family) YP_001479266.1 KEGG: kpn:KPN_01538 acetyl-CoA:acetoacetyl-CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001479267.1 KEGG: kpn:KPN_01539 acetyl-CoA:acetoacetyl-CoA transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001479268.1 TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: kpn:KPN_01540 acetyl-CoA acetyltransferase YP_001479269.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: kpn:KPN_01542 putative 3-oxoadipate enol-lactonase II YP_001479271.1 KEGG: fjo:Fjoh_2212 hypothetical protein YP_001479272.1 KEGG: csa:Csal_1644 hypothetical protein YP_001479273.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: ypp:YPDSF_1786 Mg(2+) transport ATPase protein B YP_001479274.1 PFAM: MgtC/SapB transporter; KEGG: yen:YE2586 Mg(2+) transport ATPase protein C YP_001479275.1 KEGG: aha:AHA_0614 hypothetical protein YP_001479276.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pfo:Pfl_4383 L-carnitine dehydratase/bile acid-inducible protein F YP_001479277.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bbr:BB1863 putative LysR-family transcriptional regulator YP_001479278.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: sen:SACE_3828 putative amino acid decarboxylase,pyridoxal-dependent protein YP_001479279.1 PFAM: regulatory protein LuxR; KEGG: sgl:SG1239 colanic acid capsular biosynthesis activation protein A YP_001479280.1 KEGG: eca:ECA1682 hypothetical protein YP_001479281.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yen:YE2590 cold shock-like protein CspC2 YP_001479282.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: ent:Ent638_2297 ion transport protein YP_001479284.1 KEGG: kpn:KPN_00420 hypothetical protein YP_001479285.1 TIGRFAM: Quinone oxidoreductase putative PIG3; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypi:YpsIP31758_1628 putative NAD(P)H quinone oxidoreductase, PIG3 family YP_001479286.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: psa:PST_1930 hypothetical protein YP_001479287.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: rha:RHA1_ro02434 hypothetical protein YP_001479288.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bra:BRADO3708 putative transcriptional regulatory protein, LysR family YP_001479289.1 PFAM: protein of unknown function DUF937; KEGG: bte:BTH_I2206 bacterial protein of unknown function (DUF937) family YP_001479290.1 PFAM: Transglycosylase-associated protein; KEGG: ypi:YpsIP31758_2800 hypothetical protein YP_001479291.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_A5815 transcriptional regulator, LysR family YP_001479292.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: atc:AGR_L_1000 short chain dehydrogenase YP_001479293.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: bpd:BURPS668_1165 VOC metalloenzyme family protein YP_001479295.1 KEGG: ecs:ECs3276 hypothetical protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB YP_001479296.1 KEGG: ece:Z5815 putative transposase YP_001479297.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: eca:ECA3148 putative regulator YP_001479298.1 KEGG: ypi:YpsIP31758_1624 hypothetical protein YP_001479299.1 PFAM: SMC domain protein; KEGG: cvi:CV_1280 hypothetical protein YP_001479300.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001479301.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001479302.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001479303.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein YP_001479304.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: eco:b1391 phenylacetic acid degradation protein YP_001479305.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ecj:JW1387 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_001479306.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ecj:JW1388 enoyl-CoA hydratase-isomerase YP_001479307.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001479308.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001479309.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: ecj:JW1391 predicted thioesterase YP_001479310.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001479311.1 TIGRFAM: phenylacetate-CoA ligase; KEGG: kpn:KPN_01479 phenylacetate-CoA ligase YP_001479312.1 TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: ecj:JW1394 DNA-binding transcriptional regulator, aryl-CoA responsive YP_001479313.1 TIGRFAM: phenylacetic acid degradation protein PaaY; KEGG: ecj:JW1395 predicted hexapeptide repeat acetyltransferase YP_001479314.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pfl:PFL_2405 hypothetical protein YP_001479315.1 PFAM: amino acid permease-associated region; KEGG: pfl:PFL_0763 amino acid permease YP_001479316.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001479317.1 PFAM: Endoribonuclease L-PSP; KEGG: bur:Bcep18194_B3155 endoribonuclease L-PSP YP_001479318.1 KEGG: pde:Pden_5100 esterase/lipase-like protein YP_001479319.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_2626 transcriptional regulator, LysR family YP_001479320.1 PFAM: Glutathione S-transferase domain; KEGG: mag:amb1272 glutathione S-transferase YP_001479321.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mms:mma_2628 hypothetical protein YP_001479322.1 PFAM: Glycogen synthesis protein YP_001479323.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: acr:Acry_0274 succinic semialdehyde dehydrogenase YP_001479324.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rme:Rmet_1778 glyoxalase/bleomycin resistance protein/dioxygenase YP_001479326.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: eca:ECA3135 hypothetical protein YP_001479327.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3724 putative LysR-family transcriptional regulatory protein YP_001479328.1 PFAM: Pyrrolo-quinoline quinone; KEGG: stm:STM0169 glucose dehydrogenase YP_001479330.1 TIGRFAM: oligosaccharide/H+ symporter, major facilitator superfamily (MFS); PFAM: proton/sugar symporter LacY; major facilitator superfamily MFS_1; KEGG: eca:ECA1489 lactose permease YP_001479331.1 PFAM: glycoside hydrolase family 4; KEGG: bha:BH2228 melibiase (alpha-galactosidase) YP_001479332.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: cbe:Cbei_4446 transcriptional regulator, AraC family YP_001479333.1 PFAM: chitin-binding domain 3 protein; KEGG: vco:VC0395_1137 putative chitinase YP_001479334.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: stm:STM2013 putative transport protein YP_001479335.1 KEGG: yen:YE3575 putative secretion protein YP_001479336.1 PFAM: isochorismatase hydrolase; KEGG: sbl:Sbal_0487 isochorismatase hydrolase YP_001479337.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: bxe:Bxe_A0705 transcriptional regulator, AraC family YP_001479338.1 PFAM: protein of unknown function DUF980; KEGG: yen:YE2610 hypothetical protein YP_001479339.1 KEGG: eca:ECA1481 hypothetical protein YP_001479340.1 PFAM: beta-lactamase domain protein; KEGG: spt:SPA1006 putative hydrolase YP_001479341.1 KEGG: mms:mma_2406 hypothetical protein YP_001479342.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb20366 putative transcriptional regulator protein YP_001479343.1 PFAM: extracellular solute-binding protein family 1; KEGG: bov:BOV_A0676 ABC transporter, periplasmic substrate-binding protein YP_001479344.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oan:Oant_3844 binding-protein-dependent transport systems inner membrane component YP_001479345.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: oan:Oant_3843 ABC transporter related YP_001479346.1 PFAM: inositol monophosphatase; KEGG: bme:BMEII0568 myo-inositol-1(or 4)-monophosphatase YP_001479347.1 KEGG: kpn:KPN_01710 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001479348.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: kpn:KPN_01709 putative helix-turn-helix, AraC type YP_001479349.1 PFAM: luciferase family protein; KEGG: eca:ECA3097 monooxygenase YP_001479350.1 PFAM: TENA/THI-4 domain protein; KEGG: kpn:KPN_01799 putative ABC transporter YP_001479351.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_01800 putative ABC transporter YP_001479352.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: kpn:KPN_01801 binding-protein-dependent transport systems inner membrane component YP_001479353.1 PFAM: NLPA lipoprotein; NMT1/THI5 like domain protein; KEGG: hip:CGSHiEE_01225 thiamine biosynthesis protein YP_001479354.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001479355.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001479356.1 PFAM: protein of unknown function UPF0187; KEGG: kpn:KPN_01826 hypothetical protein YP_001479357.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001479359.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: psb:Psyr_2945 regulatory protein, LysR:LysR, substrate-binding YP_001479360.1 PFAM: major facilitator superfamily MFS_1; KEGG: sco:SCO3915 putative transmembrane efflux protein YP_001479361.1 KEGG: ent:Ent638_1881 hypothetical protein YP_001479362.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001479363.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001479364.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pau:PA14_49780 probable fosfomycin resistance protein YP_001479365.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: plu:plu2641 hypothetical protein YP_001479366.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3958 probable transporter YP_001479367.1 PFAM: acriflavin resistance protein; KEGG: ent:Ent638_1874 acriflavin resistance protein YP_001479368.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ent:Ent638_1873 efflux transporter, RND family, MFP subunit YP_001479369.1 PFAM: regulatory protein TetR; KEGG: eca:ECA2931 TetR-family transcriptional regulator YP_001479370.1 PFAM: peptidase S45 penicillin amidase; KEGG: swi:Swit_0920 peptidase S45, penicillin amidase YP_001479371.1 KEGG: mmw:Mmwyl1_1177 hypothetical protein YP_001479372.1 KEGG: mmw:Mmwyl1_1176 hypothetical protein YP_001479373.1 KEGG: eca:ECA0060 hypothetical protein YP_001479374.1 PFAM: nitroreductase; KEGG: psp:PSPPH_1550 nitroreductase family protein YP_001479375.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bbr:BB2390 putative LysR-family transcriptional regulator YP_001479376.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: bpe:BP2156 hypothetical protein YP_001479377.1 PFAM: glycosyl transferase family 9; KEGG: sfu:Sfum_0372 glycosyl transferase, family 9 YP_001479378.1 PFAM: O-antigen polymerase; KEGG: sgl:SG0240 putative lipid A core surface polymer ligase YP_001479379.1 KEGG: sgl:SG2197 putative lipopolysaccharide glycosyltransferase YP_001479380.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: eca:ECA0070 hypothetical protein YP_001479381.1 PFAM: luciferase family protein; KEGG: bbt:BBta_4850 hypothetical protein YP_001479382.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0072 ABC transporter ATP-binding protein YP_001479383.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0073 ABC transporter permease protein YP_001479384.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0074 ABC transporter permease protein YP_001479385.1 PFAM: extracellular solute-binding protein family 5; KEGG: kpn:KPN_01854 nickel transport protein (ABC superfamily, peri_bind) YP_001479387.1 PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: pfo:Pfl_4187 metal-dependent hydrolase YP_001479388.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_1767 transcriptional regulator, LysR family YP_001479389.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: rpa:RPA1722 alkylated DNA repair protein YP_001479390.1 TIGRFAM: RarD protein, DMT superfamily transporter; KEGG: pen:PSEEN3058 chloramphenicol-sensitive protein RarD YP_001479391.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: eca:ECA0474 enterobactin synthetase component D (4'-phosphopantetheinyl transferase) YP_001479392.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase YP_001479393.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: yen:YE2647 citrate carrier YP_001479394.1 PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: sec:SC0648 putative modifier of citrate lyase protein YP_001479395.1 PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; KEGG: yen:YE2649 putative apo-citrate lyase phosphoribosyl-dephospho-CoA transferase YP_001479396.1 KEGG: yen:YE2650 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit YP_001479397.1 KEGG: yen:YE2651 putative citrate lyase beta chain; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase YP_001479398.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_001479399.1 KEGG: yen:YE2653 [citrate [pro-3s]-lyase] ligase; TIGRFAM: cytidyltransferase-related domain; citrate lyase ligase; PFAM: GCN5-related N-acetyltransferase; Citrate lyase ligase domain protein YP_001479400.1 PFAM: response regulator receiver; KEGG: yen:YE2655 response regulator protein YP_001479401.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001479402.1 PFAM: Ketopantoate reductase ApbA/PanE domain protein; KEGG: eca:ECA1579 probable ketopantoate reductase YP_001479403.1 PFAM: Domain of unknown function DUF1852; KEGG: eca:ECA3125 hypothetical protein YP_001479404.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001479405.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: ecj:JW0884 conserved hypothetical protein YP_001479406.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2184 putative transcriptional regulator LysR-type YP_001479407.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_02282 putative permease of the major facilitator superfamily YP_001479408.1 PFAM: extracellular solute-binding protein family 1; KEGG: kpn:KPN_02281 molybdate transport protein (ABC superfamily, peri_bind) YP_001479409.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02280 putative transcriptional regulator (LysR family) YP_001479410.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ent:Ent638_2281 alcohol dehydrogenase, zinc-binding domain protein YP_001479411.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ent:Ent638_2278 short-chain dehydrogenase/reductase SDR YP_001479412.1 PFAM: regulatory protein TetR; KEGG: ent:Ent638_2276 transcriptional regulator, TetR family YP_001479413.1 this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable reaction at the extreme temperatures these organisms live under YP_001479414.1 PFAM: amidinotransferase; KEGG: ckl:CKL_2196 hypothetical protein YP_001479415.1 PFAM: amino acid permease-associated region; KEGG: ctc:CTC00932 putative amino acid permease RocC YP_001479416.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: pth:PTH_0506 ornithine carbamoyltransferase YP_001479417.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_2911 transcriptional regulator, LysR family YP_001479418.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: bch:Bcen2424_0726 catalase/peroxidase HPI YP_001479419.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_01822 putative transport protein YP_001479420.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_2000 major facilitator superfamily MFS_1 YP_001479421.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: bsu:BG11855 unknown YP_001479422.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bsu:BG12214 hypothetical protein YP_001479423.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: mlo:mlr1005 transcriptional regulator YP_001479424.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: bch:Bcen2424_5163 aspartyl/asparaginyl beta-hydroxylase YP_001479425.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2495 ABC transporter related YP_001479426.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ent:Ent638_2494 ABC transporter related YP_001479427.1 PFAM: inner-membrane translocator; KEGG: ent:Ent638_2493 inner-membrane translocator YP_001479428.1 PFAM: inner-membrane translocator; KEGG: ent:Ent638_2492 inner-membrane translocator YP_001479429.1 PFAM: Extracellular ligand-binding receptor; KEGG: ent:Ent638_2491 extracellular ligand-binding receptor YP_001479430.1 KEGG: eca:ECA1632 hypothetical protein YP_001479431.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pae:PA2921 probable transcriptional regulator YP_001479432.1 KEGG: pau:PA14_26260 putative hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001479433.1 PFAM: extracellular solute-binding protein family 3; KEGG: bur:Bcep18194_B2597 ABC amino acid transporter, periplasmic ligand binding protein YP_001479434.1 PFAM: protein of unknown function DUF496; KEGG: ypi:YpsIP31758_2417 hypothetical protein YP_001479435.1 KEGG: yen:YE2756 hypothetical protein YP_001479436.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: ypi:YpsIP31758_1649 N-acetylmuramoyl-L-alanine amidase, family 2 YP_001479437.1 PFAM: peptidase S24 and S26 domain protein; KEGG: sgl:SG1826 putative transcriptional regulator YP_001479438.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: kpn:KPN_03122 hemolysin F YP_001479440.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001479441.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2566 putative amino acid permease YP_001479442.1 PFAM: glutamine synthetase catalytic region; KEGG: ecj:JW5201 gamma-Glu-putrescine synthase YP_001479443.1 regulates genes involved in putrescine degradation YP_001479444.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE2762 putative ABC transport system ATP-binding protein YP_001479445.1 PFAM: inner-membrane translocator; KEGG: yen:YE2763 ribose transport system, permease protein YP_001479446.1 YiuR; outer membrane siderophore receptor YP_001479447.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE1460 putative siderophore ABC transporter, ATP-binding subunit YP_001479448.1 PFAM: transport system permease protein; KEGG: ypi:YpsIP31758_2668 ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein YP_001479449.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rpa:RPA3076 putative diguanylate cyclase (GGDEF) YP_001479450.1 PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2670 lysine-specific permease LysP YP_001479451.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE1457 putative LysR-family transcriptional regulatory protein YP_001479452.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_2674 hypothetical protein YP_001479453.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001479454.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001479455.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001479456.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001479457.1 PFAM: NUDIX hydrolase; KEGG: yen:YE1446 putative Mut family protein YP_001479458.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: yen:YE1445 cytochrome c-type protein YP_001479459.1 KEGG: yen:YE1444 putative molybdopterin-containing oxidoreductase; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001479460.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2730 sugar efflux transporter YP_001479461.1 PFAM: protein of unknown function UPF0153; KEGG: ypi:YpsIP31758_2696 hypothetical protein YP_001479462.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: yen:YE1442 putative tryptophan-specific transport protein YP_001479463.1 TIGRFAM: elongation factor P-like protein YeiP; PFAM: Elongation factor P/YeiP protein; Elongation factor KOW domain protein; Elongation factor P; KEGG: ypi:YpsIP31758_2698 elongation factor P-like protein YP_001479464.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001479465.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yen:YE1438 putative D-mannonate oxidoreductase YP_001479466.1 KEGG: yen:YE1436 hypothetical protein YP_001479467.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: ypp:YPDSF_2417 cobalamin synthesis protein YP_001479468.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: yen:YE1434 hypothetical protein YP_001479470.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001479471.1 PFAM: EAL domain protein; KEGG: ypi:YpsIP31758_2710 protein rtn YP_001479472.1 PFAM: extracellular solute-binding protein family 5; KEGG: yen:YE1430 putative substrate-binding transport protein YP_001479473.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1429 putative ABC transporter integral membrane subunit YP_001479474.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2713 ABC transporter, permease protein YP_001479475.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2714 ABC transporter, ATP-binding protein YP_001479476.1 KEGG: eca:ECA2740 hypothetical protein YP_001479477.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001479478.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001479479.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: yen:YE1423 putative DEAD box helicase family protein YP_001479480.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001479481.1 PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein YP_001479482.1 PFAM: protein of unknown function DUF1414; KEGG: ypm:YP_0880 hypothetical protein YP_001479483.1 PFAM: sulfatase; KEGG: yen:YE1419 hypothetical protein YP_001479484.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001479485.1 PFAM: beta-lactamase domain protein; KEGG: sec:SC3660 putative Zn-dependent hydrolase, including glyoxylases YP_001479486.1 PFAM: regulatory protein LysR; KEGG: stm:STM3736 putative transcriptional regulator YP_001479487.1 PFAM: protein of unknown function DUF1348; KEGG: ypi:YpsIP31758_2759 hypothetical protein YP_001479488.1 PFAM: regulatory protein TetR; KEGG: ypi:YpsIP31758_2760 transcriptional regulator, TetR family YP_001479489.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rpa:RPA2469 putative lactoylglutathione lyase YP_001479490.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001479491.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1399 hypothetical protein YP_001479492.1 PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: yen:YE1398 putative two component sensor kinase YP_001479493.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001479494.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: yps:YPTB1257 two component sensor kinase/response regulator protein RcsC YP_001479495.1 negatively supercoils closed circular double-stranded DNA YP_001479496.1 Involved in ubiquinone biosynthesis YP_001479497.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001479498.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001479499.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001479500.1 PFAM: Hok/gef cell toxic protein; KEGG: kpn:KPN_03921 putative hok/gef cell toxic protein YP_001479501.1 TIGRFAM: molybdenum cofactor synthesis domain; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: yen:YE1383 hypothetical protein YP_001479502.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ypi:YpsIP31758_2774 tyrosine-specific transport protein YP_001479503.1 PFAM: YfaZ family protein; KEGG: ypi:YpsIP31758_2775 putative outer membrane protein YP_001479504.1 PFAM: Catalase domain protein; KEGG: yen:YE1380 catalase YP_001479505.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: yps:YPTB2556 O-succinylbenzoic acid--CoA ligase YP_001479506.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001479507.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001479508.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001479509.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001479510.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: yps:YPTB2561 menaquinone-specific isochorismate synthase YP_001479511.1 PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: ent:Ent638_4245 glycosyltransferase 36 YP_001479512.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sfv:SFV_2337 hypothetical protein YP_001479513.1 NAD-binding YP_001479514.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001479515.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE1364 putative LacI-family transcriptional regulatory protein YP_001479516.1 PFAM: protein of unknown function DUF1097; KEGG: yen:YE1358 hypothetical protein YP_001479517.1 PFAM: major facilitator superfamily MFS_1; KEGG: asa:ASA_3608 multi-drug efflux transporter YP_001479518.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: reu:Reut_A0878 probable transmembrane protein YP_001479519.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: psp:PSPPH_4848 hypothetical protein YP_001479520.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: stp:Strop_3951 thiamine pyrophosphate enzyme domain protein TPP-binding YP_001479521.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aha:AHA_0743 regulatory protein, LysR:LysR, substrate-binding YP_001479522.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479523.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479524.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001479525.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479526.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479527.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479528.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479529.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479530.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001479531.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479532.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001479533.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001479534.1 Catalyzes the transfer of electrons from NADH to quinone YP_001479535.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2588 LysR-family transcriptional regulatory protein YP_001479536.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001479537.1 KEGG: yen:YE1340 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_001479538.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: yps:YPTB2592 probable sodium:sulfate symporter YP_001479539.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE1337 putative haloacid dehalogenase-like hydrolase YP_001479540.1 PFAM: YfbU family protein; KEGG: yen:YE1336 hypothetical protein YP_001479541.1 PFAM: protein of unknown function DUF412; KEGG: yen:YE1335 hypothetical protein YP_001479542.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001479543.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001479544.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA3042 putative NUDIX hydrolase YP_001479545.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: ypi:YpsIP31758_1434 phosphodiesterase, MJ0936 family YP_001479546.1 PFAM: Glutathione S-transferase domain; KEGG: eca:ECA3044 putative glutathione-S transferase YP_001479547.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001479548.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; domain of unknown function DUF1731; KEGG: ypi:YpsIP31758_1432 NAD dependent epimerase/dehydratase family protein YP_001479549.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE1321 histidine transport ATP-binding protein HisP YP_001479550.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yen:YE1320 histidine transport system permease protein HisM YP_001479551.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1429 histidine ABC transporter, permease protein HisQ YP_001479552.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: yen:YE1318 histidine-binding periplasmic protein YP_001479553.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001479554.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001479555.1 membrane protein required for colicin V production YP_001479556.1 PFAM: Sporulation domain protein; KEGG: yen:YE1313 hypothetical protein YP_001479557.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: yen:YE1312 putative FolC bifunctional protein YP_001479558.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001479559.1 PFAM: SNARE associated Golgi protein; KEGG: kpn:KPN_02707 putative integral membrane protein YP_001479560.1 KEGG: eca:ECA3058 tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase YP_001479561.1 PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: ypi:YpsIP31758_1419 aspartate-semialdehyde dehydrogenase family protein YP_001479562.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yps:YPTB2620 putative D-isomer specific 2-hydroxyacid dehydrogenase YP_001479563.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE1306 putative AraC-family regulatory protein YP_001479564.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yen:YE1305 hypothetical protein YP_001479565.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: plu:plu3178 two-component sensor kinase YP_001479566.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: plu:plu3179 two-component response regulator YP_001479568.1 PFAM: conserved hypothetical protein; KEGG: plu:plu3181 putative tricarboxylic transport membrane protein YP_001479569.1 KEGG: stm:STM2787 tricarboxylic transport YP_001479570.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: plu:plu3183 TctA protein YP_001479571.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vco:VC0395_0977 antibiotic acetyltransferase YP_001479572.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yen:YE1304 putative inner membrane protein YP_001479573.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE1303 hypothetical protein YP_001479574.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: yen:YE1302 putative metal resistance protein YP_001479575.1 PFAM: DSBA oxidoreductase; KEGG: yen:YE1301 putative metal resistance protein YP_001479576.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: yen:YE1300 putative metal resistance protein YP_001479577.1 KEGG: yen:YE1299 putative metal resistance protein YP_001479578.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001479579.1 PFAM: major facilitator superfamily MFS_1; KEGG: ace:Acel_1471 major facilitator superfamily MFS_1 YP_001479580.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bvi:Bcep1808_5016 GCN5-related N-acetyltransferase YP_001479581.1 PFAM: Carbamoyltransferase; KEGG: yen:YE0544 putative transferase YP_001479582.1 KEGG: bvi:Bcep1808_5012 hypothetical protein YP_001479583.1 KEGG: bvi:Bcep1808_5012 hypothetical protein YP_001479584.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rba:RB4127 probable secreted protein YP_001479585.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001479586.1 PFAM: Citrate transporter; KEGG: yen:YE1297 putative inner membrane protein YP_001479587.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001479588.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: yen:YE3630 putative cation efflux system protein YP_001479589.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: yen:YE3629 putative efflux system protein YP_001479590.1 PFAM: outer membrane efflux protein; KEGG: yen:YE3628 outer membrane efflux protein YP_001479591.1 KEGG: yen:YE3627 hypothetical protein YP_001479592.1 KEGG: eca:ECA1387 hypothetical protein YP_001479593.1 KEGG: stm:STM3392 putative outer membrane lipoprotein YP_001479594.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001479595.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001479596.1 PFAM: YfcL protein; KEGG: kpn:KPN_02715 hypothetical protein YP_001479597.1 PFAM: protein of unknown function DUF462; KEGG: yen:YE1284 hypothetical protein YP_001479598.1 PFAM: protein of unknown function DUF81; KEGG: yen:YE1283 hypothetical protein YP_001479599.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001479600.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001479601.1 involved in methylation of ribosomal protein L3 YP_001479602.1 PFAM: Smr protein/MutS2; KEGG: yen:YE1279 hypothetical protein YP_001479603.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: yen:YE1278 putative phosphohistidine phosphatase YP_001479604.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001479605.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001479606.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA3080 hypothetical protein YP_001479607.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: kpn:KPN_02726 long-chain fatty acid transport protein (outer membrane flp protein) YP_001479608.1 PFAM: VacJ family lipoprotein; KEGG: ypi:YpsIP31758_1396 lipoprotein VacJ YP_001479609.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: yen:YE1271 VacJ lipoprotein YP_001479610.1 PFAM: cytochrome C biogenesis protein; KEGG: ypp:YPDSF_2019 cytochrome c-type biogenesis protein YP_001479611.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: yen:YE1269 thiol:disulfide interchange protein DsbE YP_001479612.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: yen:YE1268 putative cytochrome c-type biogenesis protein YP_001479613.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001479614.1 PFAM: Heme exporter protein D (CcmD); KEGG: yen:YE1266 putative heme exporter protein D YP_001479615.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: yen:YE1265 putative heme exporter protein C YP_001479616.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: ypi:YpsIP31758_1388 heme exporter protein CcmB YP_001479617.1 ATP-binding protein; required for proper cytochrome c maturation YP_001479618.1 KEGG: yen:YE1262 putative inner membrane protein YP_001479619.1 KEGG: kpn:KPN_02277 putative nucleoprotein/polynucleotide-associated enzyme YP_001479620.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001479622.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: gsu:GSU3388 hypothetical protein YP_001479623.1 KEGG: stt:t4290 hypothetical protein YP_001479624.1 KEGG: kpn:KPN_00475 putative outer membrane protein YP_001479625.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001479626.1 KEGG: yen:YE1233 hypothetical protein YP_001479627.1 PFAM: aminotransferase class I and II; KEGG: yen:YE1231 putative aminotransferase YP_001479628.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE1230 putative acetyltransferase YP_001479629.1 PFAM: protein of unknown function DUF1479; KEGG: yen:YE1229 hypothetical protein YP_001479630.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: yen:YE1228 two-component system histidine kinase YP_001479631.1 PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: yen:YE1227 putative two-component system response-regulator YP_001479632.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1226 putative membrane transport protein YP_001479633.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001479634.1 PFAM: Chloride channel core; KEGG: ecc:c2928 hypothetical protein YP_001479635.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: yen:YE1289 putative aspartate/glutamate racemase YP_001479636.1 PFAM: transmembrane pair domain protein; KEGG: yen:YE1224 hypothetical protein YP_001479637.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE1223 putative LysR-family transcriptional regulatory protein YP_001479638.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yen:YE1222 indole-3-pyruvate decarboxylase YP_001479639.1 PFAM: aldo/keto reductase; KEGG: yen:YE1221 putative ion channel protein YP_001479640.1 KEGG: ypi:YpsIP31758_1328 hypothetical protein YP_001479641.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: yen:YE1219 manganese transport protein MntH YP_001479642.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: yen:YE1217 nucleoside permease YP_001479643.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001479644.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_001479645.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: kpn:KPN_00613 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase YP_001479646.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_001479647.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: kpn:KPN_00611 isochorismate synthase YP_001479648.1 with FepCDG is involved in the transport of ferric enterobactin YP_001479649.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_001479650.1 with FepBCG is involved in the transport of ferric enterobactin YP_001479651.1 with FepBCD is involved in the transport of ferric enterobactin YP_001479652.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ecj:JW0580 iron-enterobactin transporter subunit YP_001479653.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_001479654.1 PFAM: MbtH domain protein; KEGG: tfu:Tfu_1863 putative conserved protein MbtH YP_001479655.1 PFAM: putative esterase; KEGG: yen:YE3622 enterochelin esterase YP_001479656.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001479657.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2801 periplasmic dipeptide transport protein YP_001479658.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_001479659.1 PFAM: alpha-acetolactate decarboxylase; KEGG: yen:YE4016 alpha-acetolactate decarboxylase YP_001479660.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cvi:CV_4290 probable transcriptional regulator LysR-family YP_001479661.1 PFAM: Ethanolamine ammonia-lyase light chain; KEGG: kpn:KPN_00306 ethanolamine ammonia-lyase small subunit YP_001479662.1 PFAM: Ethanolamine ammonia lyase large subunit; KEGG: asa:ASA_0956 ethanolamine ammonia-lyase, large subunit YP_001479663.1 PFAM: protein of unknown function DUF925; KEGG: yen:YE1214 hypothetical protein YP_001479664.1 KEGG: yen:YE1213 hypothetical protein YP_001479665.1 PFAM: RES domain protein; KEGG: plu:plu1483 hypothetical protein YP_001479666.1 KEGG: plu:plu1482 hypothetical protein YP_001479667.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_2936 transcriptional regulator, LysR family YP_001479668.1 PFAM: Bile acid:sodium symporter; KEGG: ssn:SSON_2498 putative cytochrome oxidase YP_001479669.1 KEGG: ypi:YpsIP31758_1322 hypothetical protein YP_001479670.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001479671.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001479672.1 putative role in sulfur assimilation YP_001479673.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001479674.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: eca:ECA0893 PTS system phosphocarrier protein YP_001479675.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001479676.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001479677.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1202 putative two-component system sensor kinase YP_001479678.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yen:YE1201 putative two-component system response regulator YP_001479679.1 TIGRFAM: cysteine synthase; cysteine synthase B; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypi:YpsIP31758_1303 cysteine synthase B YP_001479680.1 KEGG: yen:YE1197 sulfate transport ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001479681.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001479682.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1300 sulfate/thiosulfate ABC transporter, permease protein CysT YP_001479683.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_1299 sulfate/thiosulfate ABC transporter, periplasmic sulfate/thiosulfate-binding protein YP_001479684.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: ypp:YPDSF_2130 hypothetical protein YP_001479685.1 PFAM: protein of unknown function DUF1131; KEGG: ypi:YpsIP31758_1290 putative lipoprotein YP_001479686.1 KEGG: kpn:KPN_02776 hypothetical protein YP_001479687.1 PFAM: conserved hypothetical protein; KEGG: yen:YE1185 hypothetical protein YP_001479688.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ent:Ent638_2955 GCN5-related N-acetyltransferase YP_001479689.1 PFAM: cell wall hydrolase/autolysin; KEGG: ent:Ent638_2956 N-acetylmuramoyl-L-alanine amidase YP_001479690.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001479691.1 PFAM: protein of unknown function DUF188; KEGG: yen:YE1167 hypothetical protein YP_001479692.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sbo:SBO_P082 colicin Js sensitive receptor protein YP_001479693.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: plu:plu2716 protease II (oligopeptidase B) YP_001479694.1 TIGRFAM: TonB family protein; KEGG: sbo:SBO_P083 TonB-like colicin Js sensitive putative membrane protein YP_001479695.1 PFAM: protein of unknown function DUF399; KEGG: plu:plu2718 hypothetical protein YP_001479696.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2798 probable S-methylmethionine permease YP_001479697.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_001479698.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001479699.1 KEGG: ypk:y0188 hypothetical protein YP_001479700.1 KEGG: yen:YE1672 putative phagelysin YP_001479701.1 TIGRFAM: phage holin, lambda family; PFAM: Holin phage lambda; KEGG: spt:SPA2398 lysis (holin) YP_001479702.1 KEGG: sde:Sde_3870 chitinase; PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; SMART: chitinase II YP_001479703.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aav:Aave_0757 transcriptional regulator, LysR family YP_001479704.1 PFAM: chitin-binding domain 3 protein; KEGG: bca:BCE_2855 chitin binding protein, putative YP_001479705.1 KEGG: eca:ECA0862 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001479706.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001479707.1 PFAM: UreE urease accessory domain protein; KEGG: ypi:YpsIP31758_1080 urease accessory protein UreE YP_001479708.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sgl:SG1549 putative right origin-binding protein YP_001479709.1 PFAM: NUDIX hydrolase; KEGG: yen:YE1161 hypothetical protein YP_001479710.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001479711.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001479712.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001479713.1 PFAM: NapD family protein; KEGG: ypp:YPDSF_2144 hypothetical protein YP_001479714.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ypi:YpsIP31758_1271 ferredoxin-type protein NapF YP_001479715.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: eca:ECA1900 nitrate/nitrite sensor protein YP_001479716.1 PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: yen:YE1153 nitrate/nitrite response regulator protein NarP YP_001479717.1 KEGG: ypi:YpsIP31758_1269 hypothetical protein YP_001479718.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yen:YE1151 multidrug efflux protein YP_001479719.1 KEGG: yen:YE1151 multidrug efflux protein YP_001479720.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ent:Ent638_1099 TonB-dependent receptor YP_001479721.1 KEGG: ent:Ent638_1100 putative receptor YP_001479722.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: azo:azo2994 probable TonB-dependent receptor YP_001479723.1 KEGG: yen:YE1149 hypothetical protein YP_001479724.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bja:blr1088 putative GNAT family acetyltransferase YP_001479725.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_2792 probable acetyltransferase YP_001479726.1 PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1256 hypothetical protein YP_001479727.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001479728.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: ypi:YpsIP31758_1254 D-alanyl-D-alanine carboxypeptidase family protein YP_001479729.1 KEGG: yen:YE1145 hypothetical protein YP_001479730.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001479731.1 PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF699 ATPase putative; KEGG: yps:YPTB2778 putative acetyltransferase YP_001479732.1 PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: ypi:YpsIP31758_1250 metalloprotease-like protein YP_001479733.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001479734.1 PFAM: NlpBDapX family lipoprotein; KEGG: yen:YE1138 lipoprotein YP_001479735.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001479736.1 negative transcriptional regulator of the gcvTHP operon YP_001479737.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001479738.1 PFAM: protein of unknown function UPF0118; KEGG: yen:YE1133 hypothetical protein YP_001479739.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: plu:plu4154 hypothetical protein YP_001479740.1 PFAM: regulatory protein AsnC/Lrp family; Helix-turn-helix type 11 domain protein; KEGG: plu:plu4153 hypothetical protein YP_001479741.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: swi:Swit_2959 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001479742.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: swi:Swit_2958 transcriptional regulator, BadM/Rrf2 family YP_001479743.1 PFAM: peptidase M48 Ste24p; KEGG: eca:ECA1259 hypothetical protein YP_001479744.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1238 arsenate reductase (glutaredoxin) YP_001479745.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001479746.1 KEGG: kpn:KPN_01758 putative cell envelope integrity inner membrane protein TolA YP_001479747.1 PFAM: Transglycosylase-associated protein; KEGG: eca:ECA2044 hypothetical protein YP_001479748.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypi:YpsIP31758_1236 uracil permease YP_001479749.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001479750.1 KEGG: yen:YE1127 putative phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001479751.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001479752.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: csa:Csal_0195 plasmid stabilization system YP_001479753.1 KEGG: pst:PSPTOA0058 hypothetical protein YP_001479754.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_1232 spermidine N(1)-acetyltransferase YP_001479755.1 PFAM: protein of unknown function DUF596; KEGG: pmu:PM1634 unknown YP_001479756.1 KEGG: plu:plu3577 hypothetical protein YP_001479757.1 PFAM: protein of unknown function DUF596; KEGG: xft:PD2117 hypothetical protein YP_001479758.1 KEGG: xft:PD1240 hypothetical protein YP_001479759.1 KEGG: plu:plu3577 hypothetical protein YP_001479760.1 PFAM: protein of unknown function DUF596; KEGG: xft:PD1241 hypothetical protein YP_001479761.1 KEGG: xft:PD2116 hemagglutinin-like secreted protein YP_001479762.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001479763.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB2800 putative ABC phosphate transporter, permease subunit YP_001479764.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1228 phosphate ABC transporter, permease protein PstC YP_001479765.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001479766.1 PFAM: Ppx/GppA phosphatase; KEGG: ypi:YpsIP31758_1226 exopolyphosphatase YP_001479767.1 PFAM: EAL domain protein; SMART: GGDEF domain containing protein; KEGG: kpn:KPN_02828 putative cytochrome c-type biogenesis protein YP_001479768.1 KEGG: ypi:YpsIP31758_1225 hypothetical protein YP_001479769.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: yen:YE1117 putative divalent cation transport protein YP_001479770.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: ypi:YpsIP31758_3614 hypothetical protein YP_001479771.1 PFAM: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; Ada metal-binding domain protein; AlkA domain protein; KEGG: reh:H16_B2551 DNA-3-methyladenine glycosylase II, adenosine deaminase YP_001479772.1 KEGG: yen:YE1115 putative heat shock protein YP_001479773.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pat:Patl_0113 GCN5-related N-acetyltransferase YP_001479774.1 KEGG: asa:ASA_4263 predicted kinase YP_001479775.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3182 probable oxidoreductase YP_001479776.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001479777.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001479778.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001479779.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE1106 hypothetical protein YP_001479780.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yen:YE1105 two-component system, sensor kinase YP_001479781.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001479782.1 PFAM: PilT protein domain protein; KEGG: hso:HS_1769 hypothetical protein YP_001479783.1 PFAM: SpoVT/AbrB domain protein; KEGG: apl:APL_0666 hypothetical protein YP_001479784.1 PFAM: protein of unknown function DUF1508; KEGG: ypi:YpsIP31758_1209 hypothetical protein YP_001479785.1 PFAM: peptidase U32; KEGG: yen:YE1100 putative protease YP_001479786.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001479787.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 putative starvation sensing mandelate racemase / muconate lactonizing enzyme YP_001479788.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: kpn:KPN_03621 putative dehydrogenase, NAD(P)-binding, starvation-sensing protein YP_001479789.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_03622 putative transport protein YP_001479790.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 probable carbohydrate oxidoreductase YP_001479791.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: eca:ECA0921 GntR-family transcriptional regulator YP_001479792.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001479793.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: yen:YE1098 PTS system, glucitol/sorbitol-specific IIC2 component YP_001479794.1 KEGG: yen:YE1097 PTS system, glucitol/sorbitol-specific IIBC component; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein YP_001479795.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001479796.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_001479797.1 regulator for glucitol utilization YP_001479798.1 regulates genes involved in glucitol utilization YP_001479799.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_001479800.1 PFAM: Inhibitor of vertebrate lysozyme; KEGG: yps:YPTB2822 hypothetical protein YP_001479801.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001479802.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001479803.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE1087 putative acetyltransferase YP_001479804.1 PFAM: major facilitator superfamily MFS_1; KEGG: ecj:JW3845 predicted transporter YP_001479805.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ecs:ECs4795 hypothetical protein YP_001479806.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: ecs:ECs4794 putative transcriptional regulator YP_001479807.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0370 hypothetical protein YP_001479808.1 PFAM: helix-turn-helix HxlR type; KEGG: pfl:PFL_3943 hypothetical protein YP_001479809.1 PFAM: Fels-1 Propage domain protein; KEGG: bpd:BURPS668_1560 putative prophage protein YP_001479810.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ypi:YpsIP31758_2990 RNA pseudouridine synthase family protein YP_001479811.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: psp:PSPPH_0790 autotransporter, putative YP_001479812.1 KEGG: bam:Bamb_5719 hypothetical protein YP_001479813.1 PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: reh:H16_B0523 response regulator, NarL-family YP_001479814.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: reh:H16_B0524 signal transduction histidine kinase containing a receiver domain (hybrid) YP_001479815.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV492 enoyl-CoA hydratase YP_001479816.1 PFAM: helix-turn-helix HxlR type; KEGG: sma:SAV491 transcriptional regulator YP_001479817.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_2338 probable ribosomal-protein-alanine N-acetyltransferase YP_001479818.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdn:Sden_3182 major facilitator superfamily MFS_1 YP_001479819.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001479820.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001479821.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001479822.1 PFAM: glycoside hydrolase family 31; KEGG: ypi:YpsIP31758_0924 glycosyl hydrolase, family 31 protein YP_001479823.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0926 putative hexuronate transporter YP_001479824.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_0927 sugar-binding transcriptional regulator, LacI family YP_001479825.1 PFAM: peptidase M4 thermolysin; Peptidase M4 thermolysin; KEGG: eca:ECA3211 extracellular metalloprotease YP_001479826.1 KEGG: eca:ECA3212 hypothetical protein YP_001479827.1 PFAM: protein of unknown function DUF1407; KEGG: yen:YE1079 hypothetical protein YP_001479828.1 PFAM: Auxin Efflux Carrier; KEGG: yen:YE1078 hypothetical protein YP_001479829.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001479830.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001479831.1 KEGG: yen:YE1075 hypothetical protein YP_001479832.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001479833.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001479834.1 PFAM: helix-turn-helix domain protein; KEGG: ecv:APECO1_4008 hypothetical protein YP_001479835.1 KEGG: yen:YE1071 putative fimbrial biogenesis protein; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001479836.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001479837.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001479838.1 penicillin-insensitive transglycosylase/transpeptidase YP_001479839.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: yen:YE1066 hypothetical protein YP_001479840.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_1855 sugar-binding transcriptional regulator, LacI family YP_001479841.1 PFAM: Na+/H+ antiporter NhaC; KEGG: ypi:YpsIP31758_1856 Na+/H+ antiporter NhaC YP_001479842.1 PFAM: aminotransferase class I and II; KEGG: ypi:YpsIP31758_1857 aminotransferase, classes I and II YP_001479843.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001479844.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001479845.1 PFAM: protein of unknown function DUF528; KEGG: ecp:ECP_2529 hypothetical protein YfhJ YP_001479846.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: plu:plu3278 ferredoxin, 2Fe-2S YP_001479847.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001479848.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001479849.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001479850.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: ypi:YpsIP31758_1169 FeS cluster assembly scaffold IscU YP_001479851.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001479852.1 regulates the expression of the iscRSUA operon YP_001479853.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: ypi:YpsIP31758_1166 RNA methyltransferase, TrmH family, group 1 YP_001479854.1 PFAM: inositol monophosphatase; KEGG: ypi:YpsIP31758_1165 inositol-1-monophosphatase YP_001479855.1 PFAM: high-affinity nickel-transporter; KEGG: yen:YE1052 hypothetical protein YP_001479856.1 PFAM: protein of unknown function DUF1007; KEGG: yen:YE1051 hypothetical protein YP_001479857.1 PFAM: PRD domain protein; KEGG: ypa:YPA_2343 putative RNA-binding protein YP_001479858.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001479859.1 TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: amt:Amet_3027 cytidine deaminase YP_001479860.1 PFAM: protein of unknown function DUF1355; KEGG: stm:STM1381 putative cytoplasmic protein YP_001479861.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ent:Ent638_2927 nucleoside transporter YP_001479862.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001479863.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001479864.1 PFAM: cytochrome c class I; KEGG: asa:ASA_2963 cytochrome c, class I YP_001479865.1 KEGG: aha:AHA_2947 twin-arginine translocation pathway signal YP_001479866.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001479867.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pfo:Pfl_1045 binding-protein-dependent transport systems inner membrane component YP_001479868.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pen:PSEEN1240 ABC transporter, permease protein YP_001479869.1 KEGG: pfo:Pfl_1047 spermidine/putrescine ABC transporter ATP-binding subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001479870.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 putative transport protein YP_001479871.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001479872.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfo:Pfl_1050 transcriptional regulator, LysR family YP_001479873.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001479874.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001479875.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; SMART: AAA ATPase; KEGG: yen:YE1037 two-component system response regulator YP_001479876.1 KEGG: ypp:YPDSF_2259 lipoprotein YP_001479877.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1150 putative sensor-like histidine kinase YfhK YP_001479878.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001479879.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001479880.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ypi:YpsIP31758_1145 tRNA-specific adenosine deaminase YP_001479881.1 KEGG: yen:YE1029 putative integral membrane protein YP_001479882.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ent:Ent638_0142 iron-containing alcohol dehydrogenase YP_001479883.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: ypi:YpsIP31758_1144 HAD hydrolase YfhB YP_001479884.1 PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ent:Ent638_3046 phosphotransferase system, EIIC YP_001479885.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001479886.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE1025 putative RpiR-family transcriptional regulatory protein YP_001479887.1 PFAM: sulfatase; KEGG: asu:Asuc_1041 sulfatase YP_001479888.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ecv:APECO1_3969 putative 4Fe-4S cluster-containing protein YP_001479889.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001479890.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001479891.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001479892.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001479893.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001479894.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001479895.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001479896.1 KEGG: yen:YE1014 hypothetical protein YP_001479897.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001479898.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001479899.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: ypi:YpsIP31758_1130 sigma E factor negative regulatory protein YP_001479900.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001479901.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001479902.1 PFAM: methyltransferase small; KEGG: yps:YPTB2899 hypothetical protein YP_001479903.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001479904.1 PFAM: Ankyrin; KEGG: yen:YE1006 putative phospholipase A accessory protein YP_001479905.1 KEGG: yen:YE1005 phospholipase A YP_001479906.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001479907.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001479908.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001479909.1 catalyzes the phosphorylation of NAD to NADP YP_001479910.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ypi:YpsIP31758_2889 DNA repair protein RecN YP_001479911.1 PFAM: SmpA/OmlA domain protein; KEGG: stm:STM2685 small membrane protein A YP_001479912.1 PFAM: protein of unknown function UPF0125; KEGG: ypi:YpsIP31758_2891 hypothetical protein YP_001479913.1 PFAM: cyclase/dehydrase; KEGG: yen:YE0995 hypothetical protein YP_001479914.1 TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; KEGG: yen:YE0994 SsrA-binding protein (small protein B) YP_001479915.1 PFAM: HipA domain protein; KEGG: vvy:VV0798 hypothetical protein YP_001479916.1 KEGG: vco:VC0395_A0339 putative transcriptional regulator YP_001479917.1 PFAM: secretion protein HlyD family protein; KEGG: ent:Ent638_0138 secretion protein HlyD family protein YP_001479918.1 KEGG: ecs:ECs4463 hypothetical protein YP_001479919.1 KEGG: ecv:APECO1_577 hypothetical protein YP_001479920.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0144 transcriptional regulator, LysR family YP_001479921.1 KEGG: ent:Ent638_3560 VirG-like protein YP_001479922.1 KEGG: kpn:KPN_03581 hypothetical protein YP_001479923.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3067 acriflavine resistance protein A YP_001479924.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: stm:STM0475 RND family, acridine efflux pump YP_001479925.1 PFAM: MltA-interacting MipA family protein; KEGG: ypi:YpsIP31758_1990 MltA-interacting protein YP_001479926.1 KEGG: bch:Bcen2424_3890 hypothetical protein YP_001479927.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA1768 putative acetyltransferase YP_001479928.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: yen:YE1959 hypothetical protein YP_001479929.1 KEGG: ent:Ent638_3304 hypothetical protein YP_001479930.1 PFAM: DoxX family protein; KEGG: bxe:Bxe_B1209 hypothetical protein YP_001479931.1 PFAM: Smr protein/MutS2; KEGG: stm:STM1658 hypothetical protein YP_001479932.1 KEGG: yen:YE0939 hypothetical protein YP_001479933.1 KEGG: ypi:YpsIP31758_1068 hypothetical protein YP_001479934.1 KEGG: yen:YE0937 hypothetical protein YP_001479935.1 PFAM: major facilitator superfamily MFS_1; KEGG: ecj:JW5945 predicted transporter YP_001479936.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yen:YE0935 AraC-family transcriptional regulator YP_001479937.1 KEGG: yen:YE0934 hypothetical protein YP_001479938.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_1086 transcriptional regulator, LysR family YP_001479939.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_1087 major facilitator superfamily MFS_1 YP_001479940.1 KEGG: stm:STM2910 putative cytoplasmic protein YP_001479941.1 required for growth and survival under moderately acid conditions YP_001479942.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: yen:YE0932 putative inner membrane protein YP_001479943.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yen:YE0931 putative GntR-family transcriptional regulatory protein YP_001479944.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: yen:YE0930 hypothetical protein YP_001479945.1 TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: ypi:YpsIP31758_1065 glutaredoxin-related protein NrdH YP_001479946.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001479947.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001479948.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001479949.1 KEGG: azo:azo3076 conserved hypothetical protein YP_001479950.1 PFAM: protein of unknown function DUF1289; KEGG: pol:Bpro_4154 YbaK/prolyl-tRNA synthetase associated region YP_001479951.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xau:Xaut_1016 short-chain dehydrogenase/reductase SDR YP_001479952.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rle:RL3780 putative LysR family transcriptional regulator YP_001479953.1 PFAM: beta-lactamase domain protein; KEGG: mpt:Mpe_A1376 methyl parathion hydrolase YP_001479954.1 PFAM: Citrate carrier protein; KEGG: eca:ECA2576 citrate/acetate antiporter YP_001479955.1 PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: eca:ECA2577 two-component sensor kinase YP_001479956.1 PFAM: response regulator receiver; KEGG: eca:ECA2578 two-component response regulator YP_001479957.1 KEGG: yen:YE0925 glycine betaine/L-proline transport ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001479958.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001479959.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001479960.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001479961.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pen:PSEEN1556 transcriptional regulator, LysR family YP_001479962.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypn:YPN_0833 sugar transporter YP_001479963.1 PFAM: AzlC family protein; KEGG: ypi:YpsIP31758_3198 putative azaleucine resistance protein AzlC YP_001479964.1 KEGG: yen:YE3239 hypothetical protein YP_001479965.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001479966.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: yen:YE3241 probable outer membrane efflux protein YP_001479967.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: yen:YE3242 multidrug resistance protein A YP_001479968.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3202 multidrug resistance protein B YP_001479969.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: yen:YE3244 putative tRNA/rRNA methyltransferase YP_001479970.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ypi:YpsIP31758_3204 thioredoxin 2 YP_001479971.1 PFAM: DTW domain containing protein; KEGG: yen:YE3246 hypothetical protein YP_001479972.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: yps:YPTB0851 putative acyl-CoA synthetase, NAD(P)-binding, ATP-binding YP_001479973.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001479974.1 KEGG: yen:YE3251 hypothetical protein YP_001479975.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA3522 alpha-ketoglutarate permease YP_001479976.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001479977.1 part of the metNIQ transport system for methionine YP_001479978.1 part of the MetNIQ methionine uptake system YP_001479979.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: yen:YE3255 putative lipoprotein YP_001479980.1 KEGG: ypi:YpsIP31758_1040 putative lipoprotein YP_001479981.1 PFAM: protein of unknown function UPF0066; KEGG: yps:YPTB2977 hypothetical protein YP_001479982.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001479983.1 PFAM: copper resistance lipoprotein NlpE; KEGG: yen:YE3259 putative copper homeostasis lipoprotein YP_001479984.1 PFAM: Class I peptide chain release factor; KEGG: yen:YE3260 hypothetical protein YP_001479985.1 PFAM: YaeQ family protein; KEGG: ypi:YpsIP31758_1035 hypothetical protein YP_001479986.1 PFAM: protein of unknown function UPF0253; KEGG: ypi:YpsIP31758_1034 hypothetical protein YP_001479987.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: sbo:SBO_0177 hypothetical protein YP_001479988.1 PFAM: cytochrome c class I; KEGG: ypi:YpsIP31758_1032 cytochrome c family protein YP_001479989.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001479990.1 KEGG: kpn:KPN_00501 putative di-/tripeptide transport protein (POT family); TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001479991.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpn:KPN_00500 lysine decarboxylase 1 YP_001479992.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_001479993.1 regulates the cadBA operon YP_001479994.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: yen:YE3266 hypothetical protein YP_001479995.1 KEGG: pap:PSPA7_4568 hypothetical protein YP_001479996.1 PFAM: regulatory protein MarR; regulatory protein Crp; regulatory protein ArsR; KEGG: pau:PA14_52070 probable transcriptional regulator YP_001479997.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: yen:YE3267 lysine decarboxylase, constitutive YP_001479998.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001479999.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001480000.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001480001.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001480002.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001480003.1 TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: eci:UTI89_C0195 (3R)-hydroxymyristol acyl carrier protein dehydratase YP_001480004.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001480005.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: yps:YPTB2994 cationic 19 kDa outer membrane protein precursor YP_001480006.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001480007.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001480008.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001480009.1 KEGG: yen:YE3279 undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001480010.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001480011.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001480012.1 Catalyzes the phosphorylation of UMP to UDP YP_001480013.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001480014.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001480015.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001480016.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001480017.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001480018.1 KEGG: yen:YE3288 hypothetical protein YP_001480019.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001480020.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001480021.1 PFAM: protein of unknown function DUF446; KEGG: yen:YE3291 hypothetical protein YP_001480022.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bxe:Bxe_A0282 major facilitator superfamily (MFS) transporter YP_001480023.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001480024.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001480025.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1019 lysine decarboxylase family protein YP_001480026.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001480027.1 KEGG: ypi:YpsIP31758_1001 hypothetical protein YP_001480028.1 PFAM: protein of unknown function DUF423; KEGG: yen:YE3299 hypothetical protein YP_001480029.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001480030.1 PFAM: protein of unknown function DUF903; KEGG: yen:YE3302 lipoprotein YP_001480031.1 PFAM: aminotransferase class V; KEGG: kpn:KPN_03161 cysteine sulfinate desulfinase YP_001480032.1 PFAM: Fe-S metabolism associated SufE; KEGG: yps:YPTB3019 hypothetical protein YP_001480033.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: yps:YPTB3020 hypothetical protein YP_001480034.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001480035.1 PFAM: cell wall hydrolase/autolysin; KEGG: yen:YE3307 N-acetylmuramoyl-L-alanine amidase AmiC precursor YP_001480036.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001480037.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001480038.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001480039.1 PFAM: peptidase M16 domain protein; KEGG: yen:YE3311 protease III precursor YP_001480040.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001480041.1 KEGG: eca:ECA0992 putative prepilin peptidase dependent protein c precursor YP_001480042.1 KEGG: yen:YE3314 hypothetical protein YP_001480043.1 KEGG: ypi:YpsIP31758_0986 putative prepilin peptidase dependent protein YP_001480044.1 KEGG: yen:YE3316 hypothetical protein YP_001480045.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001480046.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001480047.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001480048.1 hydrolyzes diadenosine polyphosphate YP_001480049.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001480050.1 PFAM: Integral membrane protein TerC; KEGG: yen:YE3323 putative integral membrane protein YP_001480051.1 PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3050 hypothetical protein YP_001480052.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001480053.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE3326 hypothetical protein YP_001480054.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001480055.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yen:YE3330 putative biotin sulfoxide reductas2 YP_001480056.1 controls transcription of galETKM YP_001480057.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3643 GnaT-family acetyltransferase YP_001480058.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA3649 transcriptional repressor of carbon metabolism YP_001480059.1 PFAM: helix-turn-helix domain protein; KEGG: mmw:Mmwyl1_0665 putative transcriptional regulator, XRE family YP_001480060.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001480061.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001480062.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0971 transporter, major facilitator family YP_001480063.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0969 substrate-binding transcriptional regulator, LysR family YP_001480064.1 PFAM: beta-lactamase domain protein; KEGG: yps:YPTB3049 hypothetical protein YP_001480065.1 KEGG: rso:RSc1444 hypothetical protein YP_001480066.1 KEGG: spt:SPA0730 hypothetical protein YP_001480067.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase; KEGG: mms:mma_0271 ABC-type transport system, permease and ATPase components YP_001480068.1 PFAM: PTS system fructose subfamily IIA component; KEGG: plu:plu0838 unnamed protein product; similar to putative PTS system IIA component YadI of Escherichia coli YP_001480069.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: plu:plu0837 PTS system, N-acetylgalactosamine-specific IID component (EIID-AGA) (N-acetylgalactosamine-permease IID component) (phosphotransferase enzyme II, D component) YP_001480070.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: plu:plu0836 PTS system, N-acetylgalactosamine-specific IIC component 1 (EIIC-AGA) (N-acetylgalactosamine-permease IIC component 1) YP_001480071.1 KEGG: plu:plu0835 PTS system, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA') (N-acetylgalactosamine-permease IIB component 2) (phosphotransferase enzyme II, B component 2); TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component YP_001480072.1 PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: plu:plu0833 putative tagatose 6-phosphate kinase AgaZ YP_001480073.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: plu:plu0832 putative aga operon transcriptional repressor YP_001480074.1 PFAM: major facilitator superfamily MFS_1; KEGG: stm:STM1278 putative MFS family transport protein (amino acid/amine transport) YP_001480076.1 efflux pump for the antibacterial peptide microcin J25 YP_001480077.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pin:Ping_1689 transcriptional regulator, substrate-binding of LysR family protein YP_001480078.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: ppr:PBPRA2223 hypothetical L-lactate permease (LctP) YP_001480079.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001480080.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02460 putative transcriptional regulator (LysR family) YP_001480081.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: kpn:KPN_02461 putative 4-oxalocrotonate tautomerase YP_001480082.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1082 putative ABC transport protein with fused ATP binding and permease domains YP_001480083.1 KEGG: ypi:YpsIP31758_0502 hypothetical protein YP_001480084.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_001480085.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_001480086.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ent:Ent638_0201 putative cold-shock DNA-binding domain protein YP_001480087.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001480088.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_0767 transcriptional regulator, LysR family YP_001480089.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pmy:Pmen_4578 short-chain dehydrogenase/reductase SDR YP_001480090.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ava:Ava_3459 short-chain dehydrogenase/reductase SDR YP_001480091.1 PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2487 aldehyde dehydrogenase family protein YP_001480092.1 KEGG: vco:VC0395_A0804 hypothetical protein YP_001480093.1 KEGG: vpa:VP1253 NifS-related protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V YP_001480094.1 PFAM: Prophage CP4-57 regulatory; KEGG: ecv:APECO1_4024 putative phage regulatory protein YP_001480099.1 KEGG: ecv:APECO1_4054 hypothetical protein YP_001480101.1 PFAM: Lytic transglycosylase catalytic; KEGG: ecv:APECO1_4052 hypothetical protein YP_001480102.1 KEGG: net:Neut_1492 hypothetical protein YP_001480104.1 KEGG: ece:Z1446 unknown protein encoded by bacteriophage BP-933W YP_001480105.1 PFAM: P4 alpha zinc-binding domain protein; KEGG: eca:ECA2754 putative prophage primase YP_001480107.1 KEGG: ecc:c1487 hypothetical protein YP_001480108.1 PFAM: AntA/AntB antirepressor domain protein; KEGG: sbo:SBO_3650 putative anti-repressor protein YP_001480109.1 PFAM: Prophage CP4-57 regulatory; KEGG: yen:YE0975A hypothetical protein YP_001480111.1 PFAM: integrase family protein; KEGG: ypn:YPN_3086 integrase YP_001480112.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001480113.1 5'-3' single-stranded-DNA-specific exonuclease YP_001480114.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001480115.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001480116.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001480117.1 PFAM: Inner membrane CreD family protein; KEGG: yen:YE3382 hypothetical protein YP_001480118.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001480119.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001480120.1 PFAM: protein of unknown function DUF1434; KEGG: yen:YE3385 hypothetical protein YP_001480121.1 PFAM: protein of unknown function DUF339; KEGG: kpn:KPN_03325 hypothetical protein YP_001480122.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001480123.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: yps:YPTB3176 putative hemolysin III YP_001480124.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eca:ECA0756 hypothetical protein YP_001480125.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bch:Bcen2424_4787 major facilitator superfamily MFS_1 YP_001480126.1 KEGG: bbr:BB2981 hypothetical protein YP_001480127.1 PFAM: Amidase; KEGG: bbr:BB2998 putative amidase YP_001480128.1 KEGG: bbr:BB2999 hypothetical protein YP_001480129.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: xau:Xaut_0040 transcriptional regulator, GntR family YP_001480130.1 KEGG: vei:Veis_5032 putative cytoplasmic protein YP_001480131.1 PFAM: protein of unknown function DUF497; KEGG: gur:Gura_2272 protein of unknown function DUF497 YP_001480132.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_03338 putative oxidoreductase YP_001480133.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bch:Bcen2424_4924 two component transcriptional regulator, winged helix family YP_001480134.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eba:ebA6233 sensor histidine kinase YP_001480135.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: swi:Swit_2294 alcohol dehydrogenase, zinc-binding domain protein YP_001480136.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: dps:DP0247 similar to serine protease YP_001480137.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001480138.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: yen:YE3392 glycine cleavage system H protein YP_001480139.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001480140.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: yen:YE3394 putative monooxygenase YP_001480141.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001480142.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001480143.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001480144.1 PFAM: protein of unknown function DUF710; KEGG: yen:YE3398 hypothetical protein YP_001480145.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ypp:YPDSF_0601 5-formyltetrahydrofolate cyclo-ligase-family protein YP_001480146.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001480147.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001480148.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001480149.1 PFAM: protein of unknown function DUF541; KEGG: yen:YE3403 hypothetical protein YP_001480150.1 Involved in the export of arginine YP_001480151.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ecv:APECO1_2876 predicted DNA-binding transcriptional repressor YP_001480152.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pmu:PM1251 ribose transport ATP-binding protein YP_001480153.1 PFAM: inner-membrane translocator; KEGG: pmu:PM1250 ribose transport system permease YP_001480154.1 KEGG: pmu:PM1249 unknown YP_001480155.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: pmu:PM1248 gluconolactonase YP_001480156.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_001480157.1 PFAM: conserved hypothetical protein; KEGG: pmu:PM1255 hypothetical E.coli YP_001480158.1 PFAM: major facilitator superfamily MFS_1; KEGG: reh:H16_B1218 MFS transporter YP_001480159.1 PFAM: carbohydrate kinase FGGY; KEGG: eci:UTI89_C4124 cryptic L-xylulose kinase YP_001480160.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_001480161.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001480162.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001480163.1 PFAM: pseudouridine synthase; KEGG: yen:YE2636 putative ribosomal large subunit pseudouridine synthase YP_001480164.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: rso:RS01667 putative 4-hydroxybenzoate transporter transmembrane protein YP_001480165.1 PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: ypi:YpsIP31758_0851 transporter, small conductance mechanosensitive ion channel (MscS) family YP_001480166.1 PFAM: protein of unknown function DUF1345; KEGG: yen:YE0004 hypothetical protein YP_001480167.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001480168.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001480169.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001480170.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: yps:YPTB2770 probable ABC transporter, ATP-binding subunit YP_001480171.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1259 ABC transporter, permease protein YP_001480172.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2772 putative ABC transporter, periplasmmic iron binding protein YP_001480173.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: aav:Aave_1958 protein of unknown function DUF6, transmembrane YP_001480174.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: bcy:Bcer98_3652 export-related chaperone CsaA YP_001480175.1 KEGG: aor:AO090026000386 predicted protein YP_001480176.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: yen:YE3179 branched-chain amino acid transport system II carrier protein YP_001480177.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001480178.1 PFAM: peptidase M48 Ste24p; KEGG: ypi:YpsIP31758_0845 peptidase, M48 family YP_001480179.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: kpn:KPN_03360 putative pyruvate decarboxylase YP_001480180.1 PFAM: aldehyde dehydrogenase; KEGG: kpn:KPN_03361 putative aldehyde dehydrogenase YP_001480181.1 catalyzes the formation of L-aspartate to iminoaspartate in NAD(+) biosynthesis YP_001480182.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: kpn:KPN_03363 putative short-chain dehydrogenase YP_001480183.1 PFAM: alpha/beta hydrolase fold; KEGG: csa:Csal_0139 alpha/beta hydrolase YP_001480184.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: csa:Csal_0138 cupin 2 protein YP_001480185.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_03365 putative permease (MFS superfamily) YP_001480186.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: kpn:KPN_03366 putative ferredoxin reductase subunit YP_001480187.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: kpn:KPN_03367 putative glyoxalase/bleomycin resistance protein/dioxygenas YP_001480188.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: kpn:KPN_03368 putative bacterial regulatory proteins, IclR YP_001480189.1 member of a large family of NAD or NADP-dependent oxidoreductases; paralogs occur in many bacteria YP_001480190.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: kpn:KPN_03370 3-phenylpropionate dioxygenase, alpha subunit YP_001480191.1 KEGG: csa:Csal_0131 hypothetical protein YP_001480192.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: kpn:KPN_03371 putative ferredoxin YP_001480193.1 PFAM: major facilitator superfamily MFS_1; KEGG: kpn:KPN_03372 putative transport protein YP_001480194.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001480195.1 catalyzes the formation of putrescine from agmatine YP_001480196.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001480197.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001480198.1 PFAM: Hok/gef cell toxic protein; KEGG: sty:HCM1.290c putative stable plasmid inheritance protein YP_001480199.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001480200.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001480201.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001480202.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001480203.1 KEGG: sec:SC4187 putative periplasmic or exported protein YP_001480204.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001480205.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001480206.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: eca:ECA3315 2'-5' RNA ligase YP_001480207.1 PFAM: sugar fermentation stimulation protein; KEGG: ypi:YpsIP31758_3337 sugar fermentation stimulation protein YP_001480208.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: kpn:KPN_00145 DnaK suppressor protein YP_001480209.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: ypi:YpsIP31758_3339 glutamyl-Q tRNA(Asp) synthetase YP_001480210.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001480211.1 KEGG: ypi:YpsIP31758_3341 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_001480212.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: eca:ECA0007 two-component system sensor kinase YP_001480213.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: eca:ECA0008 two-component system response regulator YP_001480214.1 KEGG: ypk:y0786 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_001480215.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001480216.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001480217.1 PFAM: polysaccharide deacetylase; KEGG: ypi:YpsIP31758_3346 polysaccharide deacetylase family protein YP_001480218.1 PFAM: ABC-2 type transporter; KEGG: eca:ECA3324 ABC transporter integral membrane protein YP_001480219.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE0715 putative ABC transporter, ATP-binding protein YP_001480220.1 PFAM: carbonic anhydrase; KEGG: eca:ECA3327 putative carbonic anhydrase YP_001480221.1 KEGG: yps:YPTB0723 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001480222.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001480223.1 KEGG: yen:YE0711 hypothetical protein YP_001480224.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001480225.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001480226.1 KEGG: yen:YE1045 DNA-binding protein YP_001480227.1 PFAM: PRD domain protein; KEGG: yen:YE3102 hypothetical protein YP_001480228.1 PFAM: alanine racemase domain protein; KEGG: yen:YE3103 hypothetical protein YP_001480229.1 PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: yen:YE3104 metalloenzyme superfamily protein YP_001480230.1 PFAM: conserved hypothetical protein; KEGG: yen:YE0706 hypothetical protein YP_001480231.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001480232.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001480233.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001480234.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001480235.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001480236.1 PFAM: amino acid permease-associated region; KEGG: yen:YE0695 aromatic amino acid transport protein YP_001480237.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3792 hypothetical protein YP_001480238.1 PFAM: glycoside hydrolase family 43; KEGG: eca:ECA3793 putatuve glycosysl hydrolase YP_001480239.1 PFAM: cytochrome c class I; KEGG: rme:Rmet_1417 cytochrome c, class I YP_001480240.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rme:Rmet_1416 (2Fe-2S)-binding YP_001480241.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: bur:Bcep18194_B1541 aldehyde oxidase YP_001480242.1 KEGG: pfo:Pfl_4167 hypothetical protein YP_001480243.1 PFAM: protein of unknown function DUF182; KEGG: ppf:Pput_1633 protein of unknown function DUF182 YP_001480244.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sgl:SG0402 right origin-binding protein YP_001480245.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sfv:SFV_1628 fumarate hydratase class I, aerobic YP_001480246.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: yen:YE3424 hypothetical protein YP_001480247.1 PFAM: Endonuclease I; KEGG: ypi:YpsIP31758_0839 endonuclease I YP_001480248.1 PFAM: protein of unknown function DUF558; KEGG: ecv:APECO1_3575 hypothetical protein YP_001480249.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001480250.1 PFAM: protein of unknown function DUF179; KEGG: sgl:SG2023 hypothetical protein YP_001480251.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001480252.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein YP_001480253.1 PFAM: alanine racemase domain protein; KEGG: yps:YPTB3213 hypothetical protein YP_001480254.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001480255.1 PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein YP_001480256.1 PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein YP_001480257.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001480258.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001480259.1 PFAM: protein of unknown function DUF29; KEGG: plu:plu2339 hypothetical protein YP_001480260.1 KEGG: yen:YE3508 hypothetical protein YP_001480261.1 KEGG: jan:Jann_3434 hypothetical protein YP_001480262.1 KEGG: yen:YE3439 hypothetical protein YP_001480263.1 catalyzes the formation of glutamate from glutamine YP_001480264.1 PFAM: protein of unknown function DUF469; KEGG: yen:YE3441 hypothetical protein YP_001480265.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001480266.1 KEGG: yen:YE3443 A/G-specific adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001480267.1 PFAM: Fe(II) trafficking protein YggX; KEGG: eca:ECA0975 hypothetical protein YP_001480268.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001480269.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: asa:ASA_3304 GGDEF domain protein YP_001480270.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ypp:YPDSF_0554 ornithine decarboxylase YP_001480271.1 PFAM: integrase family protein; KEGG: eca:ECA0614 putative phage integrase YP_001480272.1 PFAM: protein of unknown function DUF1528; Relaxase; KEGG: eca:ECA0613 hypothetical protein YP_001480273.1 KEGG: eca:ECA0611 hypothetical protein YP_001480274.1 PFAM: response regulator receiver; BetR domain protein; KEGG: sec:SC042 hypothetical protein YP_001480275.1 KEGG: sec:SC041 hypothetical protein YP_001480276.1 KEGG: sec:SC040 hypothetical protein YP_001480277.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sec:SC039 hypothetical protein YP_001480278.1 KEGG: plu:plu1163 hypothetical protein YP_001480279.1 PFAM: protein of unknown function DUF1281; KEGG: ypi:YpsIP31758_3689 hypothetical protein YP_001480280.1 KEGG: yen:YE3459 hypothetical protein YP_001480281.1 PFAM: domain of unknown function DUF1738; KEGG: yen:YE3460 hypothetical protein YP_001480282.1 KEGG: stt:t4289 hypothetical protein YP_001480284.1 KEGG: stt:t4282 hypothetical protein YP_001480285.1 KEGG: plu:plu1152 hypothetical protein YP_001480287.1 KEGG: stt:t4291 UV protection protein YP_001480288.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: gbe:GbCGDNIH1_1880 hydrolase (HAD superfamily) YP_001480289.1 KEGG: mlo:mll9370 hypothetical protein YP_001480290.1 PFAM: aminotransferase class I and II; KEGG: bha:BH1695 aspartate aminotransferase YP_001480291.1 PFAM: protein of unknown function DUF201; KEGG: gka:GK2762 hypothetical protein YP_001480292.1 KEGG: bca:BCE_A0170 phosphoribosylglycinamide synthetase, ATP-grasp (A) domain protein YP_001480293.1 PFAM: major facilitator superfamily MFS_1; KEGG: btk:BT9727_3150 possible membrane protein; TGF-beta receptor, type I/II extracellular region YP_001480294.1 KEGG: eca:ECA0580 hypothetical protein YP_001480295.1 KEGG: eca:ECA0579 hypothetical protein YP_001480296.1 KEGG: eca:ECA0578 hypothetical protein YP_001480297.1 PFAM: protein of unknown function DUF1527; KEGG: eca:ECA0577 hypothetical protein YP_001480298.1 PFAM: protein of unknown function DUF1525; KEGG: eca:ECA0576 hypothetical protein YP_001480299.1 KEGG: kpn:KPN_01180 putative glycosyl transferase YP_001480300.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: ypi:YpsIP31758_0510 adhesin/haemagluttinin repeat protein YP_001480301.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: rso:RS02577 probable activation/secretion protein YP_001480302.1 PFAM: transposase IS3/IS911 family protein; KEGG: sec:SC174 hypothetical protein A YP_001480303.1 KEGG: sec:SC173 hypothetical protein B YP_001480304.1 PFAM: Integrase catalytic region; KEGG: ypp:YPDSF_4015 hypothetical protein YP_001480305.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: ypi:YpsIP31758_3536 type I restriction-modification system, M subunit YP_001480306.1 PFAM: restriction modification system DNA specificity domain; KEGG: shn:Shewana3_4163 restriction modification system DNA specificity domain YP_001480307.1 KEGG: shn:Shewana3_4164 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases YP_001480308.1 KEGG: eca:ECA0574 hypothetical protein YP_001480309.1 KEGG: eca:ECA0573 putative plasmid-related protein YP_001480310.1 KEGG: eca:ECA0572 putative lipoprotein YP_001480311.1 KEGG: eca:ECA0570 hypothetical protein YP_001480312.1 KEGG: eca:ECA0569 hypothetical protein YP_001480313.1 KEGG: eca:ECA0568 hypothetical protein YP_001480314.1 KEGG: eca:ECA0567 hypothetical protein YP_001480315.1 KEGG: plu:plu1080 hypothetical protein YP_001480316.1 KEGG: eca:ECA0565 hypothetical protein YP_001480317.1 PFAM: plasmid conserved hypothetical protein RAQPRD; KEGG: eca:ECA0564 hypothetical protein YP_001480318.1 KEGG: eca:ECA0561 hypothetical protein YP_001480319.1 KEGG: eca:ECA0560 putative plasmid transfer protein YP_001480320.1 PFAM: restriction endonuclease; KEGG: eca:ECA0558 hypothetical protein YP_001480321.1 KEGG: eca:ECA0557 hypothetical protein YP_001480322.1 PFAM: Lytic transglycosylase catalytic; KEGG: eca:ECA0556 hypothetical protein YP_001480323.1 KEGG: eca:ECA0555 hypothetical protein YP_001480324.1 KEGG: stt:t4255 hypothetical protein YP_001480325.1 KEGG: pap:PSPA7_4470 type IV B pilus protein YP_001480326.1 KEGG: acr:Acry_3623 hypothetical protein YP_001480327.1 KEGG: acr:Acry_3624 hypothetical protein YP_001480328.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: yen:YE3844 single-strand binding protein YP_001480329.1 KEGG: plu:plu1038 hypothetical protein YP_001480330.1 decatenates replicating daughter chromosomes YP_001480332.1 PFAM: Domain of unknown function DUF1845; KEGG: plu:plu1036 hypothetical protein YP_001480333.1 KEGG: plu:plu1035 hypothetical protein YP_001480334.1 KEGG: eca:ECA0522A hypothetical protein YP_001480335.1 KEGG: plu:plu1034 hypothetical protein YP_001480336.1 KEGG: eca:ECA0552 hypothetical protein YP_001480337.1 KEGG: stt:t4228 hypothetical protein YP_001480338.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: plu:plu1031 unnamed protein product; similar to DNA helicase YP_001480339.1 KEGG: eca:ECA0516 hypothetical protein YP_001480340.1 PFAM: integrase family protein; KEGG: plu:plu1166 hypothetical protein YP_001480341.1 PFAM: protein of unknown function DUF1528; Relaxase; KEGG: plu:plu1165 hypothetical protein YP_001480342.1 PFAM: regulatory protein LuxR; KEGG: asa:ASA_P5G023 hypothetical protein YP_001480343.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_2523 oxidoreductase, short chain dehydrogenase/reductase family protein YP_001480344.1 PFAM: protein of unknown function DUF1281; KEGG: ypi:YpsIP31758_3689 hypothetical protein YP_001480345.1 KEGG: yen:YE3459 hypothetical protein YP_001480346.1 PFAM: domain of unknown function DUF1738; KEGG: yen:YE3460 hypothetical protein YP_001480347.1 KEGG: stt:t4289 hypothetical protein YP_001480349.1 PFAM: helix-turn-helix domain protein; KEGG: yen:YE3496A putative DNA-binding protein YP_001480350.1 KEGG: plu:plu1152 hypothetical protein YP_001480352.1 KEGG: ypk:y2721 hypothetical protein YP_001480353.1 PFAM: ThiJ/PfpI domain protein; KEGG: plu:plu3545 hypothetical protein YP_001480354.1 KEGG: vpa:VP2147 hypothetical protein YP_001480356.1 PFAM: transcriptional regulator domain protein; KEGG: eca:ECA0944 hypothetical protein YP_001480357.1 KEGG: yen:YE3563 hypothetical protein YP_001480360.1 KEGG: plt:Plut_0869 hypothetical protein YP_001480361.1 PFAM: Fimbrial protein; KEGG: plu:plu0776 MrfG protein YP_001480362.1 KEGG: plu:plu0775 MrfF protein YP_001480363.1 PFAM: Fimbrial protein; KEGG: plu:plu0774 MrfE protein YP_001480364.1 KEGG: plu:plu0774 MrfE protein YP_001480365.1 PFAM: Fimbrial protein; KEGG: plu:plu0774 MrfE protein YP_001480366.1 PFAM: Fimbrial protein; KEGG: plu:plu0773 MrfX protein YP_001480367.1 PFAM: pili assembly chaperone; KEGG: yen:YE0782 pili chaperone protein YP_001480368.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: plu:plu0416 hypothetical protein YP_001480369.1 PFAM: Fimbrial protein; KEGG: plu:plu0770 MrfB protein YP_001480370.1 PFAM: Fimbrial protein; KEGG: ent:Ent638_0401 fimbrial protein YP_001480371.1 KEGG: plu:plu3508 hypothetical protein YP_001480372.1 PFAM: regulatory protein LuxR; KEGG: pol:Bpro_4296 two component transcriptional regulator, LuxR family YP_001480373.1 KEGG: kpn:KPN_00129 hypothetical protein YP_001480374.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: kpn:KPN_00128 hypothetical protein YP_001480375.1 PFAM: Fimbrial protein; KEGG: plu:plu0507 hypothetical protein YP_001480376.1 PFAM: pili assembly chaperone; KEGG: plu:plu0506 hypothetical protein YP_001480377.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: plu:plu0505 hypothetical protein YP_001480378.1 KEGG: plu:plu0504 hypothetical protein YP_001480381.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001480382.1 PFAM: transposase IS3/IS911 family protein; KEGG: psa:PST_3402 ISxac3 transposase YP_001480383.1 KEGG: eca:ECA0580 hypothetical protein YP_001480384.1 KEGG: eca:ECA0579 hypothetical protein YP_001480385.1 KEGG: eca:ECA0578 hypothetical protein YP_001480386.1 PFAM: protein of unknown function DUF1527; KEGG: eca:ECA0577 hypothetical protein YP_001480387.1 PFAM: protein of unknown function DUF1525; KEGG: eca:ECA0576 hypothetical protein YP_001480388.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: kpn:KPN_02993 putative transcriptional regulator (LysR family) YP_001480389.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: kpn:KPN_02994 acyl carrier protein phosphodiesterase YP_001480390.1 KEGG: eca:ECA0574 hypothetical protein YP_001480391.1 KEGG: eca:ECA0573 putative plasmid-related protein YP_001480392.1 KEGG: eca:ECA0572 putative lipoprotein YP_001480393.1 KEGG: eca:ECA0570 hypothetical protein YP_001480394.1 KEGG: eca:ECA0569 hypothetical protein YP_001480395.1 KEGG: eca:ECA0568 hypothetical protein YP_001480396.1 KEGG: eca:ECA0567 hypothetical protein YP_001480397.1 KEGG: plu:plu1080 hypothetical protein YP_001480398.1 KEGG: eca:ECA0565 hypothetical protein YP_001480399.1 PFAM: plasmid conserved hypothetical protein RAQPRD; KEGG: eca:ECA0564 hypothetical protein YP_001480400.1 KEGG: eca:ECA0561 hypothetical protein YP_001480401.1 KEGG: eca:ECA0560 putative plasmid transfer protein YP_001480402.1 PFAM: restriction endonuclease; KEGG: eca:ECA0558 hypothetical protein YP_001480403.1 KEGG: eca:ECA0557 hypothetical protein YP_001480404.1 PFAM: Lytic transglycosylase catalytic; KEGG: eca:ECA0556 hypothetical protein YP_001480405.1 KEGG: eca:ECA0555 hypothetical protein YP_001480406.1 KEGG: stt:t4255 hypothetical protein YP_001480407.1 KEGG: xac:XAC3619 hypothetical protein YP_001480409.1 PFAM: Rhs element Vgr protein; KEGG: bbr:BB0793 hypothetical protein YP_001480410.1 KEGG: bpa:BPP0711 hypothetical protein YP_001480411.1 KEGG: bbr:BB0806 hypothetical protein YP_001480412.1 PFAM: pentapeptide repeat protein; KEGG: bbr:BB0796 hypothetical protein YP_001480413.1 PFAM: pentapeptide repeat protein; KEGG: bbr:BB0795 hypothetical protein YP_001480414.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE0513 putative acetyltransferase YP_001480415.1 PFAM: regulatory protein LuxR; KEGG: yen:YE0514 putative transcriptional regulator YP_001480416.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: yen:YE0515 putative permease YP_001480417.1 SMART: helix-turn-helix domain protein; KEGG: plu:plu1490 hypothetical protein YP_001480418.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: plu:plu1489 hypothetical protein YP_001480419.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001480420.1 PFAM: phosphoesterase; protein of unknown function DUF756; KEGG: pfl:PFL_3126 phospholipase C YP_001480421.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: plu:plu3727 putative transcriptional regulator AbgR YP_001480422.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: plu:plu3726 aminobenzoyl-glutamate utilization protein A YP_001480423.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: plu:plu3725 aminobenzoyl-glutamate utilization protein B YP_001480424.1 PFAM: AbgT putative transporter; KEGG: plu:plu3724 aminobenzoyl-glutamate transport protein YP_001480425.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_001480426.1 KEGG: plu:plu1882 hypothetical protein YP_001480427.1 TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yen:YE0552 PTS system, sucrose-specific IIBC component YP_001480428.1 KEGG: yen:YE0551 sucrose-6-phosphate hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32 YP_001480429.1 KEGG: yen:YE0550A sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator YP_001480430.1 PFAM: plasmid stabilization system; KEGG: plu:plu4282 hypothetical protein YP_001480431.1 TIGRFAM: putative addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: plu:plu4283 hypothetical protein YP_001480432.1 TIGRFAM: TonB system transport protein ExbD type-1; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: plu:plu3940 biopolymer transport protein ExbD YP_001480433.1 TIGRFAM: TonB-system energizer ExbB type-1; PFAM: MotA/TolQ/ExbB proton channel; KEGG: ypm:YP_2997 TonB complex protein YP_001480434.1 catalyzes the formation of L-homocysteine from cystathionine YP_001480435.1 PFAM: SNARE associated Golgi protein; KEGG: ypi:YpsIP31758_0589 hypothetical protein YP_001480436.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: yen:YE3649 AraC-family regulatory protein YP_001480437.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA0350 putative iron-containing alcohol dehydrogenase YP_001480438.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001480439.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: ppr:PBPRA1494 putative torD protein YP_001480440.1 KEGG: ppr:PBPRA1495 putative trimethylamine-N-oxide reductase 1 precursor; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001480441.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: ecv:APECO1_89 cytochrome c-type protein TorC YP_001480442.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: pap:PSPA7_3030 transcriptional regulator, GntR family, with aminotransferase domain YP_001480443.1 PFAM: glycoside hydrolase family 1; KEGG: kpn:KPN_01961 6-phospho-beta-glucosidase A YP_001480444.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: vfi:VF0607 PTS system, diacetylchitobiose-specific IIA component YP_001480445.1 KEGG: ent:Ent638_0526 PTS system, lactose/cellobiose family IIC subunit; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_001480446.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: eca:ECA4435 pts system, IIb component YP_001480447.1 PFAM: Aldose 1-epimerase; KEGG: ecj:JW2528 conserved hypothetical protein YP_001480448.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 putative oxidoreductase YP_001480449.1 PFAM: inner-membrane translocator; KEGG: sbo:SBO_2572 putative transport system permease protein YP_001480450.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_2595 putative ATP-binding component of a transport system YP_001480451.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecc:c3070 ABC transporter Periplasmic binding protein yphF precursor YP_001480452.1 KEGG: kpn:KPN_02872 putative general substrate transporter; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001480453.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ecv:APECO1_3982 hypothetical protein YP_001480454.1 PFAM: ROK family protein; KEGG: sdy:SDY_2740 putative NAGC-like transcriptional regulator YP_001480455.1 PFAM: Lytic transglycosylase catalytic; KEGG: yps:YPTB2346 putative membrane-bound lytic murein transglycosylase YP_001480456.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: yen:YE3653 hypothetical protein YP_001480457.1 PFAM: integrase family protein; KEGG: plu:plu0768 MrfI protein YP_001480458.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bte:BTH_I2369 transcriptional regulator, AraC family domain protein YP_001480459.1 KEGG: bxe:Bxe_A4151 hypothetical protein YP_001480460.1 PFAM: cytochrome B561; KEGG: ppr:PBPRB0313 hypothetical protein YP_001480461.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_001480462.1 KEGG: eca:ECA3114 general secretion pathway lipoprotein YP_001480463.1 PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: asa:ASA_0411 type IV prepilin peptidase TapD YP_001480465.1 PFAM: General secretion pathway L; KEGG: spc:Sputcn32_3559 general secretion pathway protein L YP_001480466.1 PFAM: General secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K YP_001480467.1 TIGRFAM: general secretion pathway protein J; KEGG: yen:YE3570a putative general secretion pathway protein J precursor YP_001480468.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: yen:YE3570 general secretion pathway protein I precursor YP_001480469.1 TIGRFAM: general secretion pathway protein H; KEGG: asa:ASA_3779 general secretion pathway protein H YP_001480470.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: eca:ECA3106 general secretion pathway protein G YP_001480471.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: eca:ECA3107 general secretion pathway protein F YP_001480472.1 KEGG: aha:AHA_0570 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001480473.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpn:KPN_00160 pullulanase D protein YP_001480474.1 KEGG: yen:YE3564 general secretion pathway protein C YP_001480475.1 KEGG: ypi:YpsIP31758_0951 hypothetical protein YP_001480476.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2823 xanthosine transporter XapB YP_001480477.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001480478.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sec:SC2417 regulator for XapA (LysR family) YP_001480479.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: yen:YE3654 putative cell division protein YP_001480480.1 KEGG: ypi:YpsIP31758_0582 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001480481.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001480482.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: ypi:YpsIP31758_0580 putative NADH-quinone reductase MdaB YP_001480483.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: yen:YE3658 hypothetical protein YP_001480484.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0579 substrate-binding transcriptional regulator, LysR family YP_001480485.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001480486.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001480487.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: ypp:YPDSF_0448 Icc-like protein YP_001480488.1 PFAM: protein of unknown function DUF1249; KEGG: ent:Ent638_3446 protein of unknown function DUF1249 YP_001480489.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001480490.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001480491.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001480492.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_001480493.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: yen:YE0541 hypothetical protein YP_001480494.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001480495.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: yen:YE0539 glycerol dehydrogenase YP_001480496.1 KEGG: eca:ECA0329 hypothetical protein YP_001480497.1 PFAM: glutathionylspermidine synthase; KEGG: yen:YE3667 hypothetical protein YP_001480498.1 catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate YP_001480499.1 KEGG: pdi:BDI_3293 putative thermophilic glucose-6-phosphate isomerase-like protein YP_001480500.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: aha:AHA_2339 fructose permease IID component YP_001480501.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: aha:AHA_2340 PTS system, fructose(mannose)-specific IIC YP_001480502.1 PFAM: PTS system sorbose subfamily IIB component; KEGG: aha:AHA_2341 PTS system mannose-specific EIIAB component (EIIAB-man) YP_001480503.1 PFAM: PTS system fructose subfamily IIA component; KEGG: aha:AHA_2342 PTS system, mannose/fructose/sorbose family, IIA component YP_001480504.1 KEGG: aha:AHA_2343 hypothetical protein YP_001480505.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: aha:AHA_2344 maltose regulon regulatory protein MalI YP_001480506.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001480507.1 PFAM: zinc/iron permease; KEGG: ecv:APECO1_3371 zinc transporter ZupT YP_001480508.1 DHBP synthase; functions during riboflavin biosynthesis YP_001480509.1 PFAM: protein of unknown function DUF526; KEGG: yen:YE3671 hypothetical protein YP_001480510.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001480511.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001480512.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001480513.1 PFAM: adenylate cyclase; KEGG: yen:YE3675 hypothetical protein YP_001480514.1 SMART: SH3 domain protein; KEGG: ypi:YpsIP31758_0561 hypothetical protein YP_001480515.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001480516.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001480517.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001480518.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001480519.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001480520.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001480521.1 synthesizes RNA primers at the replication forks YP_001480522.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001480523.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: eca:ECA0679 G/U mismatch-specific DNA glycosylase YP_001480524.1 PFAM: HPP family protein?; KEGG: reh:H16_A0686 CBS-domain-containing membrane protein YP_001480525.1 PFAM: Glutathione S-transferase domain; KEGG: yen:YE1848 putative transferase YP_001480526.1 PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: kpn:KPN_03823 probable aromatic amino acid transporter YP_001480527.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: eca:ECA2054 succinate-semialdehyde dehydrogenase [NADP+] YP_001480528.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001480529.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: pin:Ping_0569 transcriptional regulator (GntR family) with HTH domain YP_001480530.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_03920 putative ATP-binding component of a transport system YP_001480531.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypi:YpsIP31758_0501 2,4-dienoyl-coa reductase YP_001480532.1 PFAM: helix-turn-helix domain protein; KEGG: pha:PSHAa0452 transcriptional regulator YP_001480533.1 PFAM: HipA domain protein; KEGG: mmw:Mmwyl1_4376 HipA domain protein YP_001480534.1 PFAM: methyltransferase small; KEGG: ypi:YpsIP31758_0500 methyltransferase family protein YP_001480535.1 PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein YP_001480536.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: plu:plu2984 hypothetical protein YP_001480537.1 PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein YP_001480538.1 PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase YP_001480539.1 PFAM: glutamine amidotransferase class-I; KEGG: bpe:BP1437 glutamine amidotransferase YP_001480540.1 PFAM: Integral membrane protein TerC; KEGG: yen:YE3703 putative drug efflux protein YP_001480541.1 involved in the import of serine and threonine coupled with the import of sodium YP_001480542.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: ypi:YpsIP31758_0493 altronate dehydratase YP_001480543.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001480544.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0644 galacturonate transporter YP_001480545.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001480546.1 KEGG: yen:YE3711 putative lipoprotein YP_001480547.1 PFAM: SNARE associated Golgi protein; KEGG: ypi:YpsIP31758_0487 hypothetical protein YP_001480548.1 KEGG: yen:YE3713 hypothetical protein YP_001480549.1 PFAM: protein of unknown function DUF1090; KEGG: ypi:YpsIP31758_0485 hypothetical protein YP_001480550.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: ypi:YpsIP31758_0483 hypothetical protein YP_001480551.1 KEGG: yen:YE3716 hypothetical protein YP_001480552.1 KEGG: eca:ECA0637 hypothetical protein YP_001480553.1 PFAM: DoxX family protein; KEGG: yen:YE3718 hypothetical protein YP_001480554.1 KEGG: yen:YE3719 hypothetical protein YP_001480555.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3720 LysR-family transcriptional regulatory protein YP_001480556.1 PFAM: Pirin domain protein; KEGG: yen:YE3721 hypothetical protein YP_001480557.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ypi:YpsIP31758_0476 putative tetrapyrrole methylase YP_001480558.1 PFAM: LppC family lipoprotein; KEGG: yen:YE3727 hypothetical protein YP_001480559.1 PFAM: protein of unknown function UPF0102; KEGG: ypi:YpsIP31758_0474 hypothetical protein YP_001480560.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001480561.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: eca:ECA0319 putative lipoprotein YP_001480562.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001480563.1 PFAM: ThiJ/PfpI domain protein; KEGG: yen:YE3732 enhancing lycopene biosynthesis protein 2 YP_001480564.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001480565.1 KEGG: yen:YE3734 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001480566.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001480567.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001480568.1 PFAM: Stringent starvation protein B; KEGG: ecv:APECO1_3216 stringent starvation protein B YP_001480569.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001480570.1 forms a direct contact with the tRNA during translation YP_001480571.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001480572.1 PFAM: AFG1-family ATPase; KEGG: yen:YE3742 hypothetical protein YP_001480573.1 PFAM: protein of unknown function DUF1043; KEGG: yen:YE3743 hypothetical protein YP_001480574.1 KEGG: eca:ECA0303 exported protease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001480575.1 KEGG: sfv:SFV_3262 protease; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001480576.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001480577.1 PFAM: BolA family protein; KEGG: yen:YE3747 BolA-like protein YP_001480578.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: ypi:YpsIP31758_0452 putative anti-anti-sigma factor YP_001480579.1 PFAM: toluene tolerance family protein; KEGG: eca:ECA0298 hypothetical protein YP_001480580.1 PFAM: Mammalian cell entry related domain protein; KEGG: eca:ECA0297 putative exported protein YP_001480581.1 PFAM: protein of unknown function DUF140; KEGG: yen:YE3751 hypothetical protein YP_001480582.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_001480583.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001480584.1 KEGG: yen:YE3754 hypothetical protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001480585.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001480586.1 PFAM: protein of unknown function DUF1239; KEGG: yen:YE3756 hypothetical protein YP_001480587.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001480588.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3758 probable ABC transporter ATP-binding protein YP_001480589.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001480590.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001480591.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: yen:YE3761 nitrogen regulatory IIA protein YP_001480592.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_0438 P-loop ATPase protein family YP_001480593.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: yen:YE3763 putative phosphocarrier protein YP_001480594.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; M trans-acting positive regulator; PRD domain protein; Helix-turn-helix type 11 domain protein; KEGG: yen:YE3777 putative transcriptional regulator YP_001480595.1 KEGG: yen:YE3778 hypothetical protein YP_001480596.1 PFAM: protein of unknown function DUF1341; KEGG: ent:Ent638_0431 protein of unknown function DUF1341 YP_001480597.1 TIGRFAM: pyridoxal phosphate-dependent enzyme, putative; PFAM: L-seryl-tRNA selenium transferase; KEGG: yen:YE3780 possible L-seryl-tRNA selenocysteine synthase YP_001480598.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001480599.1 KEGG: yen:YE3782 putative inner membrane protein YP_001480600.1 KEGG: yen:YE3783 hypothetical protein YP_001480601.1 KEGG: yen:YE3784 hypothetical protein YP_001480602.1 KEGG: yen:YE3785 hypothetical protein YP_001480603.1 PFAM: PRD domain protein; KEGG: yen:YE3786 hypothetical protein YP_001480604.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001480605.1 PFAM: cytochrome b562; KEGG: yen:YE3788 putative cytochrome YP_001480606.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001480607.1 KEGG: pna:Pnap_0994 uncharacterized conserved small protein-like protein YP_001480608.1 PFAM: protein of unknown function DUF891; KEGG: spt:SPA3745 hypothetical protein YP_001480609.1 PFAM: protein of unknown function DUF615; KEGG: yen:YE3790 hypothetical protein YP_001480610.1 PFAM: Barstar (barnase inhibitor); KEGG: yen:YE3791 putative ribonuclease inhibitor YP_001480611.1 PFAM: guanine-specific ribonuclease N1 and T1; KEGG: ypi:YpsIP31758_0423 ribonuclease Ba YP_001480612.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001480613.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001480614.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001480615.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3797 probable LysR-family transcriptional regulatory protein YP_001480617.1 KEGG: sfr:Sfri_3475 hypothetical protein YP_001480618.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: aau:AAur_3646 putative inosine-uridine preferring nucleoside hydrolase (IunH) YP_001480620.1 KEGG: ypi:YpsIP31758_0514 hypothetical protein YP_001480622.1 KEGG: ypi:YpsIP31758_0514 hypothetical protein YP_001480624.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: eci:UTI89_C4946 putative member of ShlA/HecA/FhaA exoprotein family YP_001480625.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: ent:Ent638_0052 polypeptide-transport-associated domain protein, ShlB-type YP_001480626.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001480627.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ypi:YpsIP31758_0404 hydrolase, carbon-nitrogen family protein YP_001480628.1 KEGG: yen:YE3800 hypothetical protein YP_001480629.1 involved in the processing of the 5'end of 16S rRNA YP_001480630.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001480631.1 part of cell wall structural complex MreBCD; transmembrane component YP_001480632.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001480633.1 functions in MreBCD complex in some organisms YP_001480634.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001480635.1 TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypi:YpsIP31758_0396 putative quinone oxidoreductase, YhdH/YhfP family protein YP_001480636.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001480637.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001480638.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001480639.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: eca:ECA0261 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_001480640.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001480641.1 PFAM: protein of unknown function DUF997; KEGG: ent:Ent638_3695 protein of unknown function DUF997 YP_001480642.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001480643.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001480644.1 PFAM: carbonic anhydrase; KEGG: eca:ECA0257 carbonic anhydrase YP_001480645.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; dihydroorotate dehydrogenase; KEGG: ypi:YpsIP31758_0386 dihydrouridine synthase YP_001480646.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001480647.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001480648.1 KEGG: ent:Ent638_1664 CTP synthase YP_001480649.1 PFAM: LrgB family protein; KEGG: yen:YE3837 putative inner membrane protein YP_001480650.1 PFAM: LrgA family protein; KEGG: ent:Ent638_0272 LrgA family protein YP_001480651.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3838 putative LysR family transcriptional regulator YP_001480652.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: yen:YE3839 putative putative Na(+)/H(+) exchanger protein YP_001480653.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: yps:YPTB3600 putative xanthine/uracil permease YP_001480654.1 KEGG: reh:H16_B2255 lactoylglutathione lyase YP_001480655.1 PFAM: Glutathione S-transferase domain; KEGG: yen:YE3841 putative glutathione S transferase YP_001480656.1 KEGG: yen:YE3390 hypothetical protein YP_001480657.1 PFAM: protein of unknown function DUF1471; KEGG: yen:YE2851 hypothetical protein YP_001480658.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_1861 transcriptional regulator, LysR family YP_001480659.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mms:mma_1860 oxidoreductase, short chain dehydrogenase/reductase family YP_001480660.1 PFAM: Lytic transglycosylase catalytic; SMART: extracellular solute-binding protein family 3; KEGG: kpn:KPN_04447 putative periplasmic binding protein of transport system YP_001480661.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: yen:YE3844 single-strand binding protein YP_001480662.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001480663.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bvi:Bcep1808_3188 alcohol dehydrogenase, zinc-binding domain protein YP_001480664.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: ent:Ent638_0939 transferase hexapeptide repeat containing protein YP_001480665.1 PFAM: protein of unknown function DUF419; KEGG: yen:YE3846 hypothetical protein YP_001480666.1 PFAM: protein of unknown function UPF0047; KEGG: kpn:KPN_04443 hypothetical protein YP_001480667.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001480668.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: eca:ECA3668 AsnC-family transcriptional regulator YP_001480669.1 PFAM: extracellular solute-binding protein family 3; KEGG: pfo:Pfl_3814 extracellular solute-binding protein, family 3 YP_001480670.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001480671.1 unwinds double stranded DNA YP_001480672.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA3663 quinone oxidoreductase YP_001480673.1 PFAM: protein of unknown function DUF1311; KEGG: pen:PSEEN0989 hypothetical protein YP_001480674.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001480675.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: stt:t4149 tRNA-dihydrouridine synthase A YP_001480676.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: ent:Ent638_3118 TPR repeat-containing protein YP_001480677.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: ret:RHE_CH00746 RNA polymerase sigma factor protein (sigma-24) YP_001480678.1 KEGG: pfo:Pfl_2886 predicted transmembrane transcriptional regulator (anti-sigma-factor) YP_001480679.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001480680.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001480681.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: kpn:KPN_04432 DNA-damage-inducible protein F YP_001480682.1 Represses a number of genes involved in the response to DNA damage YP_001480683.1 PFAM: diacylglycerol kinase; KEGG: sec:SC4115 diacylglycerol kinase YP_001480684.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001480685.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001480686.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001480687.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yen:YE3588 putative transporter protein YP_001480688.1 KEGG: yen:YE3589 LacI family regulatory protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_001480689.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: yen:YE3590 putative hydrolase YP_001480690.1 PFAM: Maltose operon periplasmic; KEGG: yen:YE3861 maltose operon periplasmic protein YP_001480691.1 porin involved in the transport of maltose and maltodextrins YP_001480692.1 with malEFG is involved in import of maltose/maltodextrin YP_001480693.1 KEGG: yps:YPTB3644 hypothetical protein YP_001480694.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001480695.1 with MalKGE is involved in maltose transport into the cell YP_001480696.1 with MalKFE is involved in the transport of maltose into the cell YP_001480697.1 PFAM: phosphate-starvation-inducible E; KEGG: yen:YE3869 hypothetical protein YP_001480698.1 KEGG: kpn:KPN_02513 hypothetical protein YP_001480699.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001480700.1 PFAM: sodium/hydrogen exchanger; KEGG: asa:ASA_3754 sodium/hydrogen exchanger family protein YP_001480701.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001480702.1 PFAM: Bile acid:sodium symporter; KEGG: kpn:KPN_04411 putative cytochrome oxidase YP_001480703.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: plu:plu0317 PhlA hemolysin secretion/activation protein PhlB YP_001480704.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: yps:YPTB3652 hemolysin YP_001480705.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; KEGG: eca:ECA3983 putative sodium/phosphate cotransporter YP_001480706.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: pau:PA14_21910 putative ATP-binding component of ABC transporter YP_001480707.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pap:PSPA7_1872 probable permease of ABC transporter YP_001480708.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pfl:PFL_4389 ABC transporter, permease protein YP_001480709.1 KEGG: pau:PA14_21940 hypothetical protein YP_001480710.1 PFAM: extracellular solute-binding protein family 1; KEGG: pau:PA14_21960 putative ABC transporter, periplasmic substrate-binding protein YP_001480711.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: pmy:Pmen_1333 transcriptional regulator, GntR family YP_001480712.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001480713.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001480714.1 KEGG: ppr:PBPRA2781 hypothetical protein YP_001480715.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_001480716.1 KEGG: sbo:SBO_3365 hypothetical protein YP_001480717.1 KEGG: yen:YE1040 putative integral membrane protein YP_001480718.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: reh:H16_B1238 acid phosphatase YP_001480719.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001480720.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: plu:plu0498 low-affinity gluconate transporter (gluconate permease) (Gnt-I system) YP_001480721.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001480722.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001480723.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001480724.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: ypi:YpsIP31758_0295 isocitrate lyase YP_001480725.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001480726.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001480727.1 KEGG: yen:YE3883 putative transferase YP_001480728.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001480729.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001480730.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: kpn:KPN_03684 putative DNA topoisomerase YP_001480731.1 PFAM: protein of unknown function DUF494; KEGG: eca:ECA3997 Smg protein YP_001480732.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: yen:YE3888 hypothetical protein YP_001480733.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001480734.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001480735.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001480736.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001480737.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001480738.1 PFAM: protein of unknown function DUF331; KEGG: yen:YE3894 hypothetical protein YP_001480739.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001480740.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001480741.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001480742.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001480743.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001480744.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001480745.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001480746.1 late assembly protein YP_001480747.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001480748.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001480749.1 binds 5S rRNA along with protein L5 and L25 YP_001480750.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001480751.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001480752.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001480753.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001480754.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001480755.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001480756.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001480757.1 one of the stabilizing components for the large ribosomal subunit YP_001480758.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001480759.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001480760.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001480761.1 PFAM: ribosomal protein S19/S15; KEGG: plu:plu4722 30S ribosomal protein S19 YP_001480762.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001480763.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001480764.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001480765.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001480766.1 PFAM: ribosomal protein S10; KEGG: ypi:YpsIP31758_3916 ribosomal protein S10 YP_001480767.1 iron storage protein YP_001480768.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yps:YPTB3701 putative bacterioferritin-associated ferredoxin YP_001480769.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001480770.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001480771.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001480772.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001480773.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001480774.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001480775.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001480776.1 PFAM: YheO domain protein; KEGG: yen:YE3934 putative DNA-binding protein YP_001480777.1 rotamase YP_001480778.1 PFAM: SlyX family protein; KEGG: ype:YPO0194 SlyX protein YP_001480779.1 rotamase YP_001480780.1 PFAM: conserved hypothetical protein; KEGG: yen:YE3939 hypothetical protein YP_001480781.1 involved in potassium efflux YP_001480782.1 required for KefB activity YP_001480783.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yen:YE3942 putative ATPase component of an ABC transporter YP_001480784.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001480785.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3936 taurine ABC transporter, permease protein YP_001480786.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001480787.1 with TauB and TauC is responsible for taurine uptake. YP_001480788.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bra:BRADO0445 putative oxidoreductase/dehydrogenase protein YP_001480789.1 PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_00539 putative xylose isomerase-like TIM barrel YP_001480790.1 PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: rba:RB3338 probable myo-inositol 2-dehydrogenase YP_001480791.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: asu:Asuc_0358 nucleoside:H symporter YP_001480794.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA1397 LacI-family transcriptional regulator YP_001480795.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: yen:YE3949 hypothetical protein YP_001480796.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4059 hypothetical protein YP_001480797.1 PFAM: alpha/beta hydrolase fold; KEGG: yen:YE3951 hypothetical protein YP_001480798.1 PFAM: protein of unknown function UPF0270; KEGG: yen:YE3952 hypothetical protein YP_001480799.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: yen:YE3953 phosphoribulokinase 1 YP_001480800.1 PFAM: OsmC family protein; KEGG: ypi:YpsIP31758_3944 OsmC family protein YP_001480801.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001480802.1 TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ent:Ent638_3785 integral membrane protein, YccS/YhfK family YP_001480803.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001480804.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001480805.1 PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: ypi:YpsIP31758_3949 hypothetical protein YP_001480806.1 KEGG: pmy:Pmen_3761 hypothetical protein YP_001480807.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: neu:NE0552 hypothetical protein YP_001480808.1 unknown function; when overproduced it confers drug-resistance YP_001480809.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: GAF domain protein; KEGG: ecv:APECO1_4423 putative sensory kinase in two-component system with YehT YP_001480810.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: yen:YE3960 peptidyl-prolyl cis-trans isomerase A YP_001480811.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; KEGG: plu:plu2756 PTS system, cellobiose-specific IIA component (EIIA-CEL) (cellobiose-permease IIA component) (phosphotransferase enzyme II, A component) (EIII-CEL) YP_001480812.1 PFAM: glycoside hydrolase family 4; KEGG: ypi:YpsIP31758_3951 6-phospho-beta-glucosidase YP_001480813.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_3952 sugar-binding transcriptional regulator, LacI family YP_001480814.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE3963 conserved integral membrane protein YP_001480815.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001480816.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yen:YE3965 nitrite reductase YP_001480817.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001480818.1 member of the FNT family of formate and nitrite transporters YP_001480819.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001480820.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001480821.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001480822.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: stm:STM3483 ribulose-phosphate 3-epimerase YP_001480823.1 KEGG: yen:YE3972 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001480824.1 PFAM: Sporulation domain protein; KEGG: yen:YE3973 hypothetical protein YP_001480825.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001480826.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001480827.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001480828.1 KEGG: eca:ECA4095 hypothetical protein YP_001480830.1 PFAM: Fimbrial assembly family protein; KEGG: ypp:YPDSF_0073 membrane protein YP_001480831.1 KEGG: yps:YPTB3755 hypothetical protein YP_001480832.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001480833.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001480834.1 PFAM: Intracellular growth attenuator IgaA; KEGG: yen:YE3982 hypothetical protein YP_001480835.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE3983 hypothetical protein YP_001480836.1 PFAM: RNA-binding S4 domain protein; KEGG: yen:YE3984 heat shock protein 15 YP_001480837.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001480838.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001480839.1 KEGG: pmy:Pmen_1046 hypothetical protein YP_001480840.1 PFAM: PilT protein domain protein; KEGG: csa:Csal_1070 PilT protein-like protein YP_001480841.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001480842.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001480843.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rso:RSc2243 probable transcription regulator protein YP_001480844.1 PFAM: aldehyde dehydrogenase; KEGG: bur:Bcep18194_B3062 aldehyde dehydrogenase YP_001480845.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: swi:Swit_3059 gentisate 1,2-dioxygenase YP_001480846.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pna:Pnap_2474 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_001480847.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001480848.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: yen:YE4000 putative transcription accessory protein YP_001480849.1 PFAM: FeoA family protein; KEGG: yen:YE3999 hypothetical ferrous iron transport protein A YP_001480850.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001480851.1 PFAM: Protein of unknown function DUF1920; KEGG: yen:YE3997 ferrous iron transport protein C YP_001480852.1 PFAM: protein of unknown function DUF1471; KEGG: ypi:YpsIP31758_3987 hypothetical protein YP_001480853.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA4132 putative biotin biosynthesis protein YP_001480854.1 involved in high-affinity gluconate transport YP_001480855.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001480856.1 amylomaltase; acts to release glucose from maltodextrins YP_001480857.1 KEGG: yen:YE3991 phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_001480858.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001480859.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001480860.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001480861.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001480862.1 KEGG: dvu:DVU1708 hypothetical protein YP_001480863.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001480864.1 KEGG: ypp:YPDSF_3303 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_001480865.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001480866.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001480867.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001480868.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001480869.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001480870.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001480871.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001480872.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: ypp:YPDSF_3319 gluconate permease YP_001480873.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB3798 gluconate utilization system Gnt-I transcriptional repressor YP_001480874.1 PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: ypi:YpsIP31758_4023 YhhW family protein YP_001480875.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE4024 hypothetical protein YP_001480876.1 PFAM: peptidase S58 DmpA; KEGG: hne:HNE_3147 peptidase, T4 family YP_001480877.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: yen:YE4025 hypothetical protein YP_001480878.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: kpn:KPN_04676 putative epimerase/isomerase YP_001480879.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yen:YE4026 myo-inositol 2-dehydrogenase YP_001480880.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yen:YE4027 putative thiamine pyrophosphate-dependent protein YP_001480881.1 PFAM: PfkB domain protein; KEGG: yen:YE4028 putative carbohydrate kinase YP_001480882.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yen:YE4029 hypothetical protein YP_001480883.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: yen:YE4030 hypothetical protein YP_001480884.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: yen:YE4031 putative aldehyde dehydrogenase YP_001480885.1 KEGG: stm:STM4418 sugar transporter; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001480886.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: stm:STM4435 putative cytoplasmic protein YP_001480887.1 PFAM: conserved hypothetical protein; KEGG: stm:STM0503 putative YbbM family transport protein, metal resistance protein YP_001480888.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: kpn:KPN_00468 putative ATP-binding component of a transport system YP_001480889.1 KEGG: plu:plu3508 hypothetical protein YP_001480890.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ent:Ent638_0982 peptidylprolyl isomerase, FKBP-type YP_001480891.1 KEGG: kpn:KPN_00129 hypothetical protein YP_001480892.1 PFAM: Fimbrial protein; KEGG: yps:YPTB3364 putative mannose-resistant Proteus-like fimbrial protein YP_001480893.1 PFAM: Fimbrial protein; KEGG: aha:AHA_0519 fimbrial protein YP_001480894.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: aha:AHA_0521 outer membrane usher protein YP_001480895.1 PFAM: pili assembly chaperone; KEGG: ypi:YpsIP31758_0615 chaperone protein PapD YP_001480896.1 PFAM: Fimbrial protein; KEGG: plu:plu0769 MrfA protein YP_001480897.1 KEGG: asa:ASA_3729 type I pilus assembly protein FimE YP_001480898.1 PFAM: Fimbrial protein; KEGG: asa:ASA_3730 type I pilus assembly protein FimF YP_001480899.1 PFAM: O-antigen polymerase; KEGG: asa:ASA_1459 lipid A core - O-antigen ligase YP_001480900.1 PFAM: regulatory protein LuxR; KEGG: stt:t2311 fimbriae w protein YP_001480901.1 KEGG: pen:PSEEN1860 hypothetical protein YP_001480902.1 PFAM: regulatory protein AsnC/Lrp family; Helix-turn-helix type 11 domain protein; KEGG: aci:ACIAD1283 putative transcription regulator (AsnC family) YP_001480903.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: fjo:Fjoh_3994 short-chain dehydrogenase/reductase SDR YP_001480905.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mms:mma_2322 transcriptional regulator, LysR family YP_001480906.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: tte:TTE2131 NADH:flavin oxidoreductase, Old Yellow enzyme family YP_001480907.1 KEGG: pap:PSPA7_4413 hypothetical protein YP_001480908.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bte:BTH_I2369 transcriptional regulator, AraC family domain protein YP_001480909.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypn:YPN_3615 hypothetical protein YP_001480910.1 PFAM: phosphate transporter; KEGG: yen:YE4048 phosphate transport protein YP_001480911.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001480912.1 PFAM: UspA domain protein; KEGG: sdy:SDY_3567 universal stress protein; broad regulatory function? YP_001480913.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001480914.1 KEGG: ypi:YpsIP31758_0364 carbohydrate uptake (CUT2 family) ABC transporter, periplasmic carbohydrate-binding protein YP_001480915.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0365 carbohydrate uptake (CUT2 family) ABC transporter, ATP-binding protein YP_001480916.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0366 carbohydrate uptake (CUT2 family) ABC transporter, permease protein YP_001480917.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0367 carbohydrate uptake (CUT2 family) ABC transporter, permease protein YP_001480918.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_0368 pentulose kinase, FGGY family YP_001480919.1 PFAM: sugar isomerase (SIS); KEGG: ypi:YpsIP31758_0369 SIS domain protein YP_001480920.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: eca:ECA0053 putative phosphodiesterase YP_001480921.1 predicted SAM-dependent methyltransferase YP_001480922.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: yps:YPTB3816 oligopeptidase A YP_001480923.1 PFAM: regulatory protein GntR HTH; KEGG: sde:Sde_1768 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit YP_001480924.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsh:Rsph17029_0257 TRAP dicarboxylate transporter, DctM subunit YP_001480925.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: ecv:APECO1_2070 C4-dicarboxylate transport system permease small protein YP_001480926.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: oan:Oant_3902 TRAP dicarboxylate transporter, DctP subunit YP_001480927.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA4382 putative zinc-binding dehydrogenase YP_001480928.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ent:Ent638_3295 2-deoxy-D-gluconate 3-dehydrogenase YP_001480929.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: pol:Bpro_3962 mandelate racemase/muconate lactonizing enzyme YP_001480930.1 PFAM: histidine triad (HIT) protein; KEGG: stm:STM3167 putative diadenosine tetraphosphatehydrolase YP_001480931.1 PFAM: Amidase; KEGG: bte:BTH_II1476 6-aminohexanoate-cyclic-dimer hydrolase YP_001480932.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bpl:BURPS1106A_A0260 transcriptional regulator, LysR family YP_001480933.1 PFAM: protein of unknown function DUF437; KEGG: eca:ECA0252 hypothetical protein YP_001480934.1 PFAM: protein of unknown function DUF519; KEGG: yen:YE4055 hypothetical protein YP_001480935.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001480936.1 PFAM: O-antigen polymerase; KEGG: yen:YE0777 putative inner membrane protein YP_001480937.1 KEGG: plu:plu0777 MrfH protein YP_001480938.1 PFAM: Fimbrial protein; KEGG: plu:plu0776 MrfG protein YP_001480939.1 KEGG: plu:plu0775 MrfF protein YP_001480940.1 KEGG: plu:plu0774 MrfE protein YP_001480942.1 PFAM: Fimbrial protein; KEGG: plu:plu0773 MrfX protein YP_001480943.1 PFAM: pili assembly chaperone; KEGG: yen:YE0782 pili chaperone protein YP_001480944.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: plu:plu0416 hypothetical protein YP_001480945.1 PFAM: Fimbrial protein; KEGG: plu:plu0770 MrfB protein YP_001480946.1 PFAM: Fimbrial protein; KEGG: yen:YE0779 putative mannose-resistant/Proteus-like fimbrial protein YP_001480947.1 PFAM: transcriptional regulator domain protein; KEGG: eca:ECA0944 hypothetical protein YP_001480949.1 PFAM: transcriptional regulator domain protein; KEGG: eca:ECA0944 hypothetical protein YP_001480950.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: rso:RS02477 probable hemagglutinin-related protein YP_001480951.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: eca:ECA0391 putative activator or transporter protein of haemolysin-like protein YP_001480952.1 PFAM: DinB family protein; KEGG: bch:Bcen2424_1988 DinB family protein YP_001480953.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: atc:AGR_pAT_203 hypothetical protein YP_001480954.1 KEGG: bxe:Bxe_B2768 hypothetical protein YP_001480955.1 PFAM: oxidoreductase molybdopterin binding; KEGG: bxe:Bxe_B1772 hypothetical protein YP_001480956.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sec:SC039 hypothetical protein YP_001480957.1 PFAM: response regulator receiver; BetR domain protein; KEGG: bxe:Bxe_B1770 response regulator receiver domain protein(CheY) YP_001480958.1 TIGRFAM: outer membrane autotransporter barrel domain; autotransporter-associated beta strand repeat protein; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Autotransporter beta- domain protein; KEGG: pfo:Pfl_2684 outer membrane autotransporter barrel YP_001480959.1 TIGRFAM: outer membrane autotransporter barrel domain; autotransporter-associated beta strand repeat protein; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Autotransporter beta- domain protein; KEGG: pfo:Pfl_2684 outer membrane autotransporter barrel YP_001480960.1 PFAM: regulatory protein TetR; KEGG: yps:YPTB0195 putative TetR-family regulatory protein YP_001480961.1 PFAM: protein of unknown function UPF0261; KEGG: yps:YPTB0196 hypothetical protein YP_001480962.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001480963.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001480964.1 regulator of pathogenicity factor RpfF; involved in synthesis of a diffusible signal factor involved in the regulation of extracellular enzymes YP_001480965.1 TIGRFAM: putative ribonuclease; PFAM: ribonuclease BN; KEGG: yen:YE4060 hypothetical protein YP_001480966.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA0769 probable transporter YP_001480967.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: yen:YE4061 CDP-diacylglycerol pyrophosphatase YP_001480968.1 PFAM: AsmA family protein; KEGG: yen:YE4062 hypothetical protein YP_001480969.1 in Escherichia coli this protein is involved in flagellar function YP_001480970.1 TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: yps:YPTB3829 possible tautomerase enzyme YP_001480971.1 PFAM: PfkB domain protein; KEGG: ypi:YpsIP31758_4062 2-dehydro-3-deoxygluconokinase YP_001480972.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001480973.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001480974.1 KEGG: eca:ECA4224 hypothetical protein YP_001480976.1 KEGG: sfr:Sfri_3972 hypothetical protein YP_001480977.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001480978.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001480979.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001480980.1 KEGG: yen:YE0149 acetolactate synthase isozyme II small subunit YP_001480981.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001480982.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: kpn:KPN_01755 putative transporter YP_001480983.1 KEGG: eca:ECA4230 probable magnesium-chelatase; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001480984.1 PFAM: protein of unknown function DUF413; KEGG: yen:YE0146 hypothetical protein YP_001480985.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001480986.1 membrane component of a putative sugar ABC transporter system YP_001480987.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB0129 ABC ribose/sugar transporter, permease domain YP_001480988.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_3519 sugar transport system ATP-binding protein YP_001480989.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yen:YE0141 putative periplasmic protein precursor YP_001480990.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001480991.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001480992.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001480993.1 PFAM: protein of unknown function DUF1422; KEGG: eca:ECA4240 hypothetical protein YP_001480994.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001480995.1 catalyzes the conversion of NADPH to NADH YP_001480996.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001480997.1 KEGG: yen:YE0132 putative peroxiredoxin/glutaredoxin family protein; TIGRFAM: glutaredoxin-family domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; glutaredoxin; glutaredoxin 2; Redoxin domain protein YP_001480998.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001480999.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001481000.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001481001.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001481002.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001481003.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001481004.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001481005.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001481006.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001481007.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001481008.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001481009.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001481010.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001481011.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001481012.1 TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: yen:YE0106 cell division protein YP_001481013.1 heat shock protein involved in degradation of misfolded proteins YP_001481014.1 heat shock protein involved in degradation of misfolded proteins YP_001481015.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001481016.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001481017.1 PFAM: protein of unknown function DUF904; KEGG: yen:YE0101 hypothetical protein YP_001481018.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: eca:ECA4266 glycerol uptake facilitator protein YP_001481019.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: yen:YE0099 glycerol kinase YP_001481020.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001481021.1 multidrug efflux protein involved in adaptation to low energy shock YP_001481022.1 KEGG: ppr:PBPRA0239 hypothetical protein YP_001481023.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: yen:YE0096 ferredoxin--NADP reductase YP_001481024.1 PFAM: protein of unknown function DUF805; KEGG: yen:YE0095 hypothetical protein YP_001481025.1 PFAM: protein of unknown function DUF1454; KEGG: yen:YE0094 hypothetical protein YP_001481026.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001481027.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_0090 sulfate ABC transporter, sulfate-binding protein YP_001481028.1 KEGG: stm:STM4062 6-phosphofructokinase I; TIGRFAM: 6-phosphofructokinase; PFAM: phosphofructokinase YP_001481029.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001481030.1 KEGG: stm:STM4060 periplasmic repressor of cpx regulon by interaction with CpxA, rescue from transitory stresses YP_001481031.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001481032.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001481033.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001481034.1 KEGG: yen:YE3598 hypothetical protein YP_001481035.1 catalyzes the O-acetylation of serine YP_001481036.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001481037.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001481038.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: yen:YE0079 glutaredoxin YP_001481039.1 PFAM: Rhodanese domain protein; KEGG: yen:YE0078 hypothetical protein YP_001481040.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001481041.2 PFAM: peptidase M23B; KEGG: ypi:YpsIP31758_0074 peptidase, M23 family domain protein YP_001481042.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: yen:YE0075 hypothetical protein YP_001481043.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sdy:SDY_4094 biodegradative arginine decarboxylase YP_001481044.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001481045.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001481046.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001481047.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001481048.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: ypi:YpsIP31758_0068 lipopolysaccharide heptosyltransferase I YP_001481049.1 KEGG: sgl:SG2197 putative lipopolysaccharide glycosyltransferase YP_001481050.1 PFAM: O-antigen polymerase; KEGG: sgl:SG0240 putative lipid A core surface polymer ligase YP_001481051.1 PFAM: glycosyl transferase family 9; KEGG: sfu:Sfum_0372 glycosyl transferase, family 9 YP_001481052.1 KEGG: plu:plu4850 WalW protein YP_001481053.1 TIGRFAM: lipopolysaccharide heptosyltransferase III, putative; PFAM: glycosyl transferase family 9; KEGG: plu:plu4853 lipopolysaccharide core biosynthesis glycosyl transferase RfaQ YP_001481054.1 PFAM: glycosyl transferase group 1; KEGG: kpn:KPN_03969 glucuronic acid transferase YP_001481055.1 PFAM: glycosyl transferase group 1; KEGG: sgl:SG2200 putative lipopolysaccharide glycosyltransferase YP_001481056.1 PFAM: glycosyl transferase family 9; KEGG: dar:Daro_0162 glycosyl transferase, family 9 YP_001481057.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001481058.1 PFAM: glycosyl transferase family 2; KEGG: yen:YE0068 lipopolysaccharide core biosynthesis glycosyl transferase YP_001481059.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001481060.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001481061.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001481062.1 required for 70S ribosome assembly YP_001481063.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001481064.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001481065.1 catalyzes the formation of dUMP from dUTP YP_001481066.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001481067.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001481068.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001481069.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: yen:YE0057 hypothetical protein YP_001481070.1 PFAM: Pyrrolo-quinoline quinone; KEGG: psb:Psyr_3930 quinoprotein YP_001481071.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: sen:SACE_4169 esterase/lipase YP_001481072.1 PFAM: regulatory protein TetR; KEGG: fal:FRAAL5169 putative TetR-family transcriptional regulator YP_001481073.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ypi:YpsIP31758_2550 paraquat-inducible protein A YP_001481074.1 PFAM: Mammalian cell entry related domain protein; KEGG: yen:YE1574 putative paraquat-inducible protein B YP_001481075.1 PFAM: protein of unknown function DUF330; KEGG: yen:YE1575 putative lipoprotein protein YP_001481076.1 PFAM: Strictosidine synthase; SMP-30/Gluconolaconase/LRE domain protein; KEGG: mgi:Mflv_4863 strictosidine synthase YP_001481077.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yen:YE3797 probable LysR-family transcriptional regulatory protein YP_001481078.1 KEGG: mmr:Mmar10_2665 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001481079.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bur:Bcep18194_C7556 short-chain dehydrogenase/reductase SDR YP_001481080.1 PFAM: AMP-dependent synthetase and ligase; KEGG: reh:H16_A2076 long-chain-fatty-acid--CoA ligase YP_001481082.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: yen:YE0051 nucleoside permease YP_001481083.1 KEGG: yen:YE0050 hypothetical protein YP_001481084.1 PFAM: protein of unknown function UPF0126; KEGG: ypi:YpsIP31758_0043 hypothetical protein YP_001481085.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_2915 transcriptional regulator, LysR family YP_001481086.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfl:PFL_2916 major facilitator family transporter YP_001481087.1 Essential for recycling GMP and indirectly, cGMP YP_001481088.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001481089.1 KEGG: yen:YE0045 guanosine-3',5'-bisbis(diphosphate) 3'-pyrophosphydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001481090.1 specifically modifies tRNA at position G18 YP_001481091.1 catalyzes branch migration in Holliday junction intermediates YP_001481092.1 PFAM: sodium/glutamate symporter; KEGG: ypi:YpsIP31758_0036 sodium/glutamate symporter YP_001481093.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypi:YpsIP31758_0034 xanthine permease YP_001481094.1 PFAM: AsmA family protein; KEGG: yen:YE0040 possible exported protein YP_001481095.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Carbohydrate-binding family V/XII; KEGG: mxa:MXAN_1967 putative peptidase, S8 (subtilisin) family YP_001481096.1 TIGRFAM: thioesterase domain, putative; PFAM: GCN5-related N-acetyltransferase; Thioesterase putative; KEGG: ypi:YpsIP31758_0032 acetyltransferase, GNAT family/thioesterase domain YP_001481097.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001481098.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001481099.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yen:YE0030 hypothetical protein YP_001481100.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: eca:ECA0030 GTP-binding regulatory protein YP_001481101.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001481102.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001481103.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001481104.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001481105.1 PFAM: protein of unknown function DUF414; KEGG: yen:YE0023 hypothetical protein YP_001481106.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001481107.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001481108.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: kpn:KPN_04171 putative endonuclease YP_001481109.1 PFAM: DSBA oxidoreductase; KEGG: yen:YE0020 secreted thiol:disulfide interchange protein DsbA YP_001481110.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001481111.1 PFAM: protein of unknown function DUF1040; KEGG: yen:YE0018 hypothetical protein YP_001481112.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001481113.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001481114.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: yen:YE0014 putative GntR-family transcriptional regulator YP_001481115.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB0010 MFS multidrug:H+ antiporter YP_001481116.1 DNA-binding transcriptional repressor of ribose metabolism YP_001481117.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001481118.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001481119.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001481120.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001481121.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001481122.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001481123.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001481124.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001481125.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001481126.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001481127.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001481128.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001481129.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA