-- dump date 20120504_161515 -- class Genbank::CDS -- table cds_note -- id note YP_748702.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_748703.1 KEGG: son:SO0009 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_748704.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_748705.1 KEGG: son:SO0011 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_748706.1 SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO0013 hypothetical protein YP_748707.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_748708.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_748709.1 KEGG: son:SO0016 DNA-3-methyladenine glycosidase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_748710.1 PFAM: amidohydrolase; WD40 domain protein beta Propeller; KEGG: son:SO0017 hypothetical amidohydrolase YP_748711.1 KEGG: son:SO0018 hypothetical protein YP_748712.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_748713.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_748714.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_748715.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_748716.1 PFAM: protein of unknown function UPF0029; KEGG: son:SO0023 conserved hypothetical protein TIGR00257 YP_748717.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: son:SO0024 potassium uptake protein TrkH YP_748718.1 KEGG: son:SO0025 protoporphyrinogen oxidase YP_748719.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0026 transcriptional regulator, ArsR family YP_748720.1 KEGG: son:SO0027 protoporphyrinogen oxidase YP_748721.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: son:SO0028 potassium uptake protein TrkH YP_748722.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_748723.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: son:SO0030 Sun protein YP_748724.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: son:SO0031 methionyl-tRNA formyltransferase YP_748725.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_748726.1 PFAM: Peptidoglycan-binding LysM; KEGG: son:SO0033 LysM domain protein YP_748727.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: son:SO0034 DNA processing protein DprA, putative YP_748728.1 PFAM: protein of unknown function DUF494; KEGG: son:SO0035 Smg protein YP_748729.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: son:SO0036 topoisomerase DNA-binding C4 zinc finger domain protein YP_748730.1 PFAM: SUA5/yciO/yrdC, N-terminal domain protein; KEGG: son:SO0037 Sua5/YciO/YrdC/YwlC family protein YP_748731.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_748732.1 PFAM: globin; KEGG: son:SO0039 hypothetical globin YP_748733.1 PFAM: amidohydrolase; KEGG: pha:PSHAa1729 enzyme YP_748734.1 PFAM: amidohydrolase; KEGG: cps:CPS_3629 amidohydrolase family protein YP_748735.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_748736.1 KEGG: vfi:VF2534 hypothetical protein YP_748737.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO3556 cyclic nucleotide phosphodiesterase, putative YP_748738.1 KEGG: son:SO0042 carbonic anhydrase, family 3 YP_748739.1 KEGG: son:SO4734 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_748740.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO4733 lysophospholipase L2 YP_748741.1 PFAM: protein of unknown function DUF885; KEGG: son:SO4732 hypothetical protein YP_748742.1 catalyzes the formation of inosine from adenosine YP_748743.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_748744.1 PFAM: protein of unknown function DUF833; KEGG: son:SO0126 hypothetical protein YP_748745.1 KEGG: son:SO0127 hypothetical protein YP_748746.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO0129 conserved hypothetical protein TIGR00427 YP_748748.1 PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: son:SO0130 protease, putative YP_748749.1 PFAM: Chorismate lyase; KEGG: son:SO0131 putative chorismate--pyruvate lyase YP_748750.1 PFAM: flagellar basal body-associated protein FliL; KEGG: son:SO0132 flagellar protein FliL, putative YP_748751.1 PFAM: protein of unknown function DUF890; KEGG: ppr:PBPRB0892 hypothetical SAM-dependent methyltransferase YP_748752.1 PFAM: formate dehydrogenase, subunit FdhD; KEGG: son:SO4503 formate dehydrogenase accessory protein FdhD, putative YP_748753.1 KEGG: son:SO4504 hypothetical protein YP_748754.1 KEGG: son:SO4505 hypothetical protein YP_748755.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein YP_748756.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO4507 TorA specific chaperone, putative YP_748757.1 TIGRFAM: Twin-arginine translocation pathway signal; KEGG: son:SO4508 hypothetical protein YP_748758.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO4509 formate dehydrogenase, alpha subunit YP_748759.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4510 formate dehydrogenase, iron-sulfur subunit YP_748760.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: son:SO4511 formate dehydrogenase, C subunit, putative YP_748761.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: ilo:IL1764 lipoprotein A family protein YP_748763.1 KEGG: cps:CPS_2860 hypothetical protein YP_748764.1 KEGG: jan:Jann_3567 hypothetical protein YP_748765.1 PFAM: alpha/beta hydrolase fold; KEGG: ilo:IL1807 alpha/beta superfamily hydrolase YP_748766.1 KEGG: cps:CPS_2539 ZIP zinc transporter family protein YP_748767.1 KEGG: atc:AGR_C_3952 hypothetical protein YP_748768.1 KEGG: vfi:VF1386 acetyltransferase, GNAT family YP_748769.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: pha:PSHAb0256 transporter involved in threonine and homoserine efflux YP_748772.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: vfi:VF2138 two-component sensor histidine kinase YP_748773.1 PFAM: small multidrug resistance protein; KEGG: sec:SC050 quaternary ammonium compound resistance protein YP_748774.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: cac:CAC3392 NADH-dependent butanol dehydrogenase YP_748775.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: dps:DP1867 similar to transcription regulator (AraC-type) YP_748776.1 KEGG: vpa:VPA1414 hypothetical protein YP_748777.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_748778.1 PFAM: PfkB domain protein; KEGG: son:SO4458 carbohydrate kinase, PfkB family YP_748779.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: son:SO4456 hypothetical protein YP_748780.1 KEGG: son:SO4455 hypothetical protein YP_748781.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO4454 methyl-accepting chemotaxis protein YP_748782.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: son:SO4453 electron transfer flavoprotein-ubiquinone oxidoreductase, putative YP_748783.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_748784.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_748785.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: son:SO4450 molybdenum cofactor biosynthesis protein D YP_748786.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: son:SO4449 molybdenum cofactor biosynthesis protein E YP_748787.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO4448 molybdenum ABC transporter, periplasmic molybdenum-binding protein YP_748788.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4447 molybdenum ABC transporter, permease protein YP_748789.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO4446 molybdenum ABC transporter, ATP-binding protein YP_748790.1 KEGG: son:SO4429 hypothetical protein YP_748791.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4428 DNA-binding response regulator YP_748792.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase YP_748793.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: pha:PSHAa1657 23S rRNA pseudouridylate synthase YP_748794.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4425 GGDEF family protein YP_748795.1 PFAM: protein of unknown function UPF0057; KEGG: vpa:VPA0409 plasma membrane protein involved in salt tolerance YP_748796.1 KEGG: son:SO4421 hypothetical protein YP_748797.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_748798.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: son:SO0138 molybdopterin biosynthesis MoeA protein YP_748799.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: son:SO0145 hypothetical URI domain endonuclease YP_748800.1 KEGG: hch:HCH_00813 hypothetical protein YP_748801.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: son:SO0152 hypothetical carboxypeptidase YP_748802.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_748803.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_748804.1 PFAM: RNA-binding S4 domain protein; KEGG: son:SO0164 heat shock protein 15 YP_748805.1 TIGRFAM: general secretion pathway protein C; KEGG: son:SO0165 general secretion pathway protein C YP_748806.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: son:SO0166 general secretion pathway protein D YP_748807.1 KEGG: son:SO0167 general secretion pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_748808.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: son:SO0168 general secretion pathway protein F YP_748809.1 TIGRFAM: general secretion pathway protein G; PFAM: methylation site containing protein; Bacterial type II secretion system protein G; KEGG: son:SO0169 general secretion pathway protein G YP_748810.1 TIGRFAM: general secretion pathway protein H; Prepilin-type cleavage/methylation-like; KEGG: son:SO0170 general secretion pathway protein H YP_748811.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; methylation site containing protein; KEGG: son:SO0171 general secretion pathway protein I YP_748812.1 TIGRFAM: general secretion pathway protein J; PFAM: methylation site containing protein; KEGG: son:SO0172 general secretion pathway protein J YP_748813.1 PFAM: General secretion pathway protein K; KEGG: son:SO0173 general secretion pathway protein K YP_748814.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: son:SO0174 general secretion pathway protein L YP_748815.1 PFAM: General secretion pathway M protein; KEGG: son:SO0175 general secretion pathway protein M YP_748816.1 PFAM: type II secretion system protein N; KEGG: son:SO0176 general secretion pathway protein N YP_748817.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family YP_748818.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_748819.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: son:SO0191 cysQ protein YP_748820.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_748821.1 catalyzes the formation of selenophosphate from selenide and ATP YP_748822.1 KEGG: son:SO0193 transcriptional regulator, TetR family YP_748823.1 PFAM: phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; KEGG: son:SO0194 acyltransferase family protein YP_748824.1 PFAM: fatty acid desaturase; KEGG: son:SO0197 fatty acid desaturase, family 1 YP_748825.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_748826.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_748827.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_748828.1 PFAM: RNP-1 like RNA-binding protein; KEGG: son:SO0208 RNA-binding protein YP_748829.1 KEGG: son:SOA0117 hypothetical protein YP_748830.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_748831.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_748832.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_748833.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_748834.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_748835.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_748836.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_748837.1 KEGG: son:SO0219 transcription antitermination protein NusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_748838.1 binds directly to 23S ribosomal RNA YP_748839.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_748840.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_748841.1 PFAM: ribosomal protein L7/L12; KEGG: son:SO0223 50S ribosomal protein L7/L12 YP_748842.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_748843.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_748844.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_748845.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_748846.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_748847.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_748848.1 PFAM: ribosomal protein S10; KEGG: son:SO0230 30S ribosomal protein S10 YP_748849.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_748850.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_748851.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_748852.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_748853.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_748854.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_748855.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_748856.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_748857.1 one of the stabilizing components for the large ribosomal subunit YP_748858.1 PFAM: ribosomal protein S17; KEGG: son:SO0240 30S ribosomal subunit protein S17 YP_748859.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_748860.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_748861.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_748862.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_748863.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_748864.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_748865.1 binds 5S rRNA along with protein L5 and L25 YP_748866.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_748867.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_748868.1 late assembly protein YP_748869.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_748870.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_748871.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_748872.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_748873.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_748874.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_748875.1 is a component of the macrolide binding site in the peptidyl transferase center YP_748876.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_748877.1 PFAM: Heme exporter protein D (CcmD); KEGG: son:SO0260 heme exporter protein CcmD YP_748878.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: son:SO0261 heme exporter protein CcmC YP_748879.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: son:SO0262 heme exporter protein CcmB YP_748880.1 ATP-binding protein; required for proper cytochrome c maturation YP_748881.1 PFAM: cytochrome c, class I; KEGG: son:SO0264 cytochrome c YP_748882.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0265 cytochrome c-type biogenesis protein CcmH YP_748883.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: son:SO0266 cytochrome c-type biogenesis protein CcmF YP_748884.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: son:SO0267 thiol:disulfide interchange protein DsbE YP_748885.1 PFAM: cytochrome C biogenesis protein; KEGG: son:SO0268 cytochrome c-type biogenesis protein CcmH YP_748886.1 PFAM: Redoxin domain protein; KEGG: son:SO0269 thioredoxin, putative YP_748887.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: son:SO0272 competence/damage-inducible protein CinA YP_748888.1 KEGG: son:SO1096 hypothetical protein YP_748889.1 PFAM: protein of unknown function DUF1439; KEGG: son:SO0273 hypothetical protein YP_748890.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_748891.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_748892.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_748893.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_748894.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_748895.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_748896.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_748897.1 KEGG: vfi:VF2053 hypothetical protein YP_748898.1 KEGG: cps:CPS_0837 hypothetical protein YP_748899.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: hch:HCH_06939 FOG: GGDEF domain YP_748900.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: gox:GOX0587 membrane-bound aldehyde dehydrogenase, large subunit YP_748901.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: gox:GOX0586 membrane-bound aldehyde dehydrogenase, small subunit YP_748902.1 PFAM: cytochrome c, class I; KEGG: gox:GOX0585 cytochrome c subunit of aldehyde dehydrogenase YP_748905.1 PFAM: PepSY-associated TM helix domain protein; KEGG: pfo:Pfl_0927 aspartate kinase YP_748906.1 PFAM: Pirin domain protein domain protein; Cupin 2, conserved barrel domain protein; KEGG: vpa:VPA0042 hypothetical protein YP_748907.1 PFAM: DoxX family protein; KEGG: vpa:VPA0043 hypothetical protein YP_748908.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3318 transcriptional regulator, LysR family YP_748909.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl_5034 major facilitator superfamily MFS_1 YP_748910.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ppr:PBPRB1652 putative transcriptional regulator, LysR family YP_748911.1 PFAM: aldo/keto reductase; KEGG: xcb:XC_0279 oxidoreductase YP_748912.1 PFAM: regulatory protein, MerR; KEGG: sde:Sde_1934 putative transcriptional regulator, MerR family YP_748913.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: ilo:IL1218 cation transport ATPase YP_748914.1 KEGG: ilo:IL1217 likely secreted protein containing plastocyanin domain YP_748915.1 KEGG: ilo:IL1543 hypothetical protein YP_748916.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO4640 antioxidant, AhpC/Tsa family YP_748917.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO4635 methyl-accepting chemotaxis protein YP_748918.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_748919.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_748921.1 converts protoheme IX and farnesyl diphosphate to heme O YP_748922.1 PFAM: cytochrome C oxidase subunit IV; KEGG: cvi:CV3993 cytochrome o ubiquinol oxidase subunit IV YP_748923.1 PFAM: cytochrome c oxidase, subunit III; KEGG: pha:PSHAa2229 cytochrome o ubiquinol oxidase subunit III (ubiquinol oxidase chain C) YP_748924.1 PFAM: cytochrome c oxidase, subunit I; KEGG: pha:PSHAa2230 ubiquinol oxidase polypeptide I (cytochrome o subunit 1) (oxidase BO(3) subunit 1) (cytochrome o ubiquinol oxidase subunit 1) (ubiquinol oxidase chain A) YP_748925.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: pha:PSHAa2231 ubiquinol oxidase polypeptide II (cytochrome o subunit 2) (oxidase BO(3) subunit 2) (cytochrome o ubiquinol oxidase subunit 2) (ubiquinol oxidase chain B) YP_748927.1 PFAM: regulatory protein, TetR; KEGG: ppr:PBPRB1080 hypothetical protein YP_748928.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ppr:PBPRB1079 hypothetical oxidoreductase protein YP_748929.1 PFAM: regulatory protein RecX; KEGG: vfi:VFA0909 putative regulatory protein RecX YP_748930.1 PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II YP_748931.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: hch:HCH_06874 aconitate hydratase 1 YP_748932.1 KEGG: tbd:Tbd_2287 putative integral membrane protein YP_748933.1 TIGRFAM: acetoin reductases; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ilo:IL0792 acetoin(diacetyl) reductase YP_748934.1 KEGG: bce:BC2320 hypothetical protein YP_748935.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: vpa:VP0152 transcription elongation factor GreB YP_748936.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein YP_748937.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: vfi:VFA0210 integral membrane protein YP_748938.1 PFAM: diacylglycerol kinase; KEGG: pha:PSHAa2773 diacylglycerol kinase (DAGK) YP_748939.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: vfi:VFA0211 transcriptional regulator YP_748940.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: pha:PSHAa2776 sensor transduction kinase (copper resistance) YP_748941.1 PFAM: sulfatase; KEGG: son:SO4628 sulfatase YP_748942.1 KEGG: son:SO4627 hypothetical protein YP_748943.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: son:SO4626 bioH protein YP_748944.1 KEGG: son:SO4625 competence protein ComF YP_748945.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_748946.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: cvi:CV0705 probable FkbP-type peptidyl-prolyl cis-trans isomerase YP_748947.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; phospholipase/Carboxylesterase; KEGG: son:SO4618 prolyl oligopeptidase family protein YP_748948.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO4617 DNA-damage-inducible protein F YP_748949.1 PFAM: polysaccharide deacetylase; KEGG: son:SO4616 polysaccharide deacetylase family protein YP_748950.1 PFAM: electron transport protein SCO1/SenC; KEGG: son:SO4615 SCO1/SenC family protein YP_748951.1 converts protoheme IX and farnesyl diphosphate to heme O YP_748952.1 PFAM: cytochrome oxidase assembly; KEGG: son:SO4613 cytochrome oxidase assembly protein, putative YP_748953.1 KEGG: son:SO4612 hypothetical protein YP_748954.1 KEGG: son:SO4611 hypothetical protein YP_748955.1 KEGG: son:SO4610 hypothetical protein YP_748956.1 PFAM: cytochrome c oxidase, subunit III; KEGG: son:SO4609 cytochrome c oxidase subunit III YP_748957.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_748958.1 PFAM: cytochrome c oxidase, subunit I; KEGG: son:SO4607 cytochrome c oxidase, subunit I YP_748959.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region; KEGG: son:SO4606 cytochrome c oxidase, subunit II YP_748960.1 KEGG: son:SO4604 hypothetical protein YP_748961.1 Represses a number of genes involved in the response to DNA damage YP_748962.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_748963.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: son:SO4601 tryptophan-specific transport protein YP_748964.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO4600 antigen, putative YP_748967.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SOA0153 heavy metal efflux pump, CzcA family YP_748968.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SOA0154 heavy metal efflux protein, putative YP_748969.1 KEGG: son:SO4597 heavy metal efflux system protein, putative YP_748970.1 KEGG: son:SOA0156 hypothetical protein YP_748971.1 KEGG: cps:CPS_0735 hypothetical protein YP_748972.1 KEGG: cps:CPS_0734 hypothetical protein YP_748973.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO4591 tetraheme cytochrome c YP_748975.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: son:SO4587 putative methylase YP_748976.1 KEGG: son:SO4586 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; SMART: AAA ATPase YP_748977.1 KEGG: son:SO4585 cell division ABC transporter, ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_748978.1 PFAM: protein of unknown function DUF214; KEGG: son:SO4584 cell division ABC transporter, permease protein FtsX YP_748979.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_748980.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO4576 O-succinylbenzoic acid--CoA ligase YP_748981.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_748982.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO4574 hydrolase, alpha/beta fold family YP_748983.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_748984.1 KEGG: son:SO4563 hypothetical protein YP_748985.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: son:SO4567 transcriptional regulator, AsnC family YP_748986.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_748987.1 PFAM: protein of unknown function DUF1332; KEGG: son:SO4562 hypothetical protein YP_748988.1 KEGG: son:SO4561 hypothetical protein YP_748989.1 KEGG: son:SO4560 hypothetical protein YP_748990.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO4559 hypothetical protein YP_748991.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: cps:CPS_3372 putative transporter YP_748994.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; Male sterility C-terminal; KEGG: pha:PSHAa2082 hypothetical protein YP_748997.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4556 transcriptional regulator, LysR family YP_748998.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4555 drug resistance transporter, Bcr/CflA family protein YP_749000.1 PFAM: DTW domain containing protein; KEGG: son:SO4554 hypothetical protein YP_749001.1 KEGG: son:SO4551 hypothetical protein YP_749002.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4550 methyltransferase domain protein YP_749003.1 KEGG: ilo:IL0586 metal-dependent hydrolase of the aminoacylase-2/carboxypeptidase-Z family; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_749004.1 PFAM: peptidase M16 domain protein; KEGG: son:SO4537.2 hypothetical Zn-dependent peptidase YP_749005.1 PFAM: peptidase M16 domain protein; KEGG: ppr:PBPRB1337 hypothetical protein YP_749006.1 KEGG: son:SO4535 hypothetical protein YP_749007.1 KEGG: son:SO3676 hypothetical protein YP_749008.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: son:SO4529 RNA methyltransferase, TrmH family, group 2 YP_749009.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pha:PSHAa2520 mechanosensitive channel protein YP_749010.1 PFAM: protein of unknown function UPF0057; KEGG: rru:Rru_A2519 hypothetical protein YP_749011.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA YP_749012.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4477 transcriptional regulatory protein CpxR YP_749013.1 KEGG: son:SO0975 hypothetical protein YP_749014.1 KEGG: son:SO4476 spheroplast protein y precursor, putative YP_749015.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: son:SO4475 cation efflux family protein YP_749016.1 PFAM: catalytic domain of components of various dehydrogenase complexes; KEGG: xft:PD1809 dihydrolipoamide acetyltranferase YP_749017.1 KEGG: pca:Pcar_0332 hypothetical protein YP_749018.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: reu:Reut_B5552 alpha/beta hydrolase fold:biotin/lipoyl attachment YP_749019.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: reu:Reut_B5551 transketolase, central region:transketolase, C-terminal YP_749020.1 PFAM: dehydrogenase, E1 component; KEGG: bur:Bcep18194_A5140 pyruvate dehydrogenase (lipoamide) YP_749021.1 KEGG: son:SO4472 nitrogen regulation protein NR(I); TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_749022.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4471 nitrogen regulation protein YP_749023.1 KEGG: son:SO4470 hypothetical protein YP_749024.1 PFAM: protein of unknown function DUF1255; KEGG: son:SO4467 hypothetical protein YP_749025.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: son:SO4408 virulence regulator BipA YP_749026.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_749027.1 KEGG: rfr:Rfer_2487 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_749028.1 PFAM: methylation site containing protein; KEGG: hch:HCH_06146 type II secretory pathway, pseudopilin PulG YP_749029.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: pha:PSHAa0053 transcriptional regulator YP_749030.1 KEGG: son:SO4403 hypothetical protein YP_749031.1 KEGG: son:SO4402 hypothetical protein YP_749032.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_749033.1 PFAM: D-tyrosyl-tRNA(Tyr) deacylase; KEGG: son:SO4398 D-Tyr-tRNA(Tyr) deacylase YP_749034.1 TIGRFAM: thioesterase domain, putative; KEGG: son:SO4397 hypothetical acetyltransferase YP_749035.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_749036.1 PFAM: electron transport protein SCO1/SenC; KEGG: sde:Sde_0045 GGDEF YP_749037.1 PFAM: chemotaxis sensory transducer; KEGG: pha:PSHAb0277 putative methyl-accepting chemotaxis protein YP_749038.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_749039.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_749040.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: son:SO4381 thioester dehydrase family protein YP_749041.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_749042.1 KEGG: son:SO4379 hypothetical protein YP_749043.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: son:SO4378 FAD-binding protein YP_749044.1 KEGG: son:SO4377 hypothetical protein YP_749045.1 KEGG: son:SO4376 hypothetical protein YP_749046.1 KEGG: son:SO4375 hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_749047.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO4374 histidine ammonia-lyase, putative YP_749048.1 PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: son:SO4373 glycosyl transferase, group 2 family protein YP_749049.1 KEGG: son:SO4372 thioester dehydrase family protein YP_749050.1 KEGG: son:SO4371 hypothetical protein YP_749051.1 KEGG: son:SO4370 hypothetical protein YP_749052.1 carries the fatty acid chain in fatty acid biosynthesis YP_749053.1 KEGG: son:SO4368 acyl carrier protein, putative YP_749054.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO4367 acyltransferase family protein YP_749055.1 KEGG: son:SO4366 hypothetical protein YP_749056.1 KEGG: son:SO4365 hypothetical protein YP_749057.1 catalyzes branch migration in Holliday junction intermediates YP_749058.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO0351 DNA-binding response regulator, LuxR family YP_749059.1 PFAM: histidine kinase, dimerisation and phosphoacceptor region; KEGG: son:SO0352 sensor histidine kinase, putative YP_749060.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0353 TPR domain protein YP_749061.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: son:SO0354 sodium/calcium exchanger YP_749062.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0355 AMP-binding protein YP_749063.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: son:SO0358 endoribonuclease L-PSP, putative YP_749064.1 KEGG: son:SO0359 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_749065.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_749066.1 Essential for recycling GMP and indirectly, cGMP YP_749067.1 KEGG: son:SO0362 hypothetical protein YP_749068.1 PFAM: aminoglycoside phosphotransferase; KEGG: son:SO0364 hypothetical protein YP_749069.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_749070.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: son:SO0280 penicillin-binding protein 1A YP_749071.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: son:SO0281 type IV pilus biogenesis protein PilM YP_749072.1 PFAM: Fimbrial assembly family protein; KEGG: son:SO0282 type IV pilus biogenesis protein PilN YP_749073.1 PFAM: Pilus assembly protein, PilO; KEGG: son:SO0283 type IV pilus biogenesis protein PilO YP_749074.1 PFAM: Pilus assembly protein, PilQ; KEGG: son:SO0284 type IV pilus biogenesis protein PilP YP_749075.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain protein; KEGG: son:SO0285 type IV pilus biogenesis protein PilQ YP_749076.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_749077.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_749078.1 PFAM: Sporulation domain protein; KEGG: son:SO0288 DamX domain protein YP_749079.1 KEGG: son:SO0289 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_749080.1 KEGG: son:SO0290 hypothetical protein YP_749081.1 KEGG: son:SO0291 hypothetical protein YP_749082.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: son:SO0292 ribulose-phosphate 3-epimerase YP_749083.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0293 phosphoglycolate phosphatase YP_749084.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_749085.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0295 transcriptional regulator, LysR family YP_749086.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO0296 integral membrane domain protein YP_749087.1 PFAM: transport-associated; KEGG: son:SO0297 lipoprotein, putative YP_749088.1 TIGRFAM: phosphoheptose isomerase; KEGG: son:SO0298 phosphoheptose isomerase YP_749089.1 PFAM: protein of unknown function UPF0102; KEGG: son:SO0299 predicted endonuclease YP_749090.1 PFAM: LppC family lipoprotein; KEGG: son:SO0300 lipoprotein, putative YP_749091.1 TIGRFAM: Protein of unknown function UPF0011; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO0301 hypothetical methyltransferase YP_749092.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: xcb:XC_2846 iron receptor YP_749093.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sde:Sde_2885 histidine kinase YP_749094.1 KEGG: son:SO0306 hypothetical protein YP_749095.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO0308 hypothetical protein YP_749096.1 KEGG: son:SO0309 hypothetical protein YP_749097.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO0311 hypothetical Fe-S oxidoreductase YP_749098.1 KEGG: son:SO0321 hypothetical protein YP_749099.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: son:SO4548 transposase, IS110 family YP_749101.1 KEGG: lpn:lpg2572 hypothetical protein YP_749102.1 KEGG: son:SO0322 hypothetical protein YP_749103.1 KEGG: son:SO0323 hypothetical protein YP_749104.1 KEGG: son:SO0324 hypothetical protein YP_749105.1 KEGG: son:SO0326 hypothetical protein YP_749107.1 PFAM: protein of unknown function UPF0061; KEGG: son:SO0330 hypothetical protein YP_749108.1 KEGG: son:SO0331 hypothetical protein YP_749109.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_749110.1 PFAM: DSBA oxidoreductase; KEGG: son:SO0333 thiol:disulfide interchange protein DsbA YP_749111.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO0334 hypothetical protein YP_749112.1 PFAM: protein of unknown function DUF904; KEGG: son:SO0335 hypothetical protein YP_749113.1 PFAM: Endoribonuclease L-PSP; KEGG: son:SO0337 hypothetical translation initiation inhibitor, YjgF family YP_749114.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_749115.1 KEGG: son:SO0341 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_749116.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0347 acyltransferase family protein YP_749117.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0348 acyltransferase family protein YP_749118.1 KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_749119.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO4351 CBS domain protein YP_749120.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_749121.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_749122.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_749123.1 KEGG: son:SO4346 acetolactate synthase small subunit YP_749124.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_749125.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_749126.1 PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V YP_749127.1 PFAM: protein of unknown function DUF526; KEGG: son:SO4329 hypothetical protein YP_749128.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: son:SO4325 ATP-dependent DNA helicase Rep YP_749129.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: son:SO4324 GGDEF domain protein YP_749130.1 PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO4323 GGDEF domain protein YP_749131.1 KEGG: son:SO4322 hypothetical protein YP_749132.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO4321 OmpA family protein YP_749133.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: son:SO4320 agglutination protein YP_749134.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: son:SO4319 HlyD family secretion protein YP_749135.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; peptidase C39, bacteriocin processing; SMART: AAA ATPase; KEGG: son:SO4318 toxin secretion ATP-binding protein YP_749136.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A; Cadherin; KEGG: pfo:Pfl_0133 von Willebrand factor, type A YP_749137.1 PFAM: HemY domain protein; KEGG: son:SO4316 HemY protein YP_749138.1 PFAM: protein of unknown function DUF513, hemX; KEGG: son:SO4315 hemX protein YP_749139.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: son:SO4314 uroporphyrinogen-III synthase YP_749140.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_749141.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_749142.1 PFAM: Frataxin family protein; KEGG: son:SO4311 CyaY protein YP_749143.1 KEGG: son:SO4310 hypothetical protein YP_749144.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: son:SO4309 diaminopimelate decarboxylase YP_749145.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_749146.1 PFAM: protein of unknown function DUF484; KEGG: son:SO4307 hypothetical protein YP_749147.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO4306 integrase/recombinase XerC YP_749148.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4305 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_749149.1 PFAM: AAA-4 family protein; KEGG: son:SO4303 hypothetical protein YP_749150.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: son:SO4302 hypothetical protein YP_749151.1 PFAM: Kelch repeat-containing protein; Kelch repeat protein; KEGG: cps:CPS_3966 kelch motif domain protein YP_749152.1 PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV YP_749153.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_749154.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase; KEGG: son:SO0394 tRNA-dihydrouridine synthase B YP_749155.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_749156.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_749157.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_749158.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_749159.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_749160.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: son:SO0406 thioredoxin 1 YP_749161.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_749162.1 PFAM: Ppx/GppA phosphatase; KEGG: son:SO0408 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase YP_749163.1 KEGG: son:SO0409 hypothetical protein YP_749164.1 PFAM: Integrase, catalytic region; KEGG: par:Psyc_0937 putative transposase OrfB YP_749165.1 KEGG: dde:Dde_2987 transposase YP_749166.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_749167.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, transmembrane region; KEGG: son:SO4207 GGDEF domain protein YP_749168.1 PFAM: TatD-related deoxyribonuclease; KEGG: son:SO4206 hydrolase, TatD family YP_749169.1 KEGG: son:SO4205 hypothetical protein YP_749170.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: son:SO4204 Sec-independent periplasmic protein translocation protein TatC YP_749171.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: son:SO4203 Sec-independent protein translocase protein TatB YP_749172.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: son:SO4202 Sec-independent protein translocase protein TatA YP_749173.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: son:SO4201 ubiquinone biosynthesis protein AarF YP_749174.1 PFAM: protein of unknown function DUF1243; KEGG: son:SO4200 conserved hypothetical protein YP_749175.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4199 ubiquinone/menaquinone biosynthesis methlytransferase UbiE YP_749176.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: son:SO4198 arginase family protein YP_749177.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_749178.1 KEGG: son:SO4196 hypothetical protein YP_749179.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: son:SO4195 PAP2 family protein YP_749180.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO4194 hypothetical protein YP_749181.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_749182.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_749184.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: cps:CPS_0650 sensor histidine kinase YP_749185.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sde:Sde_3703 response regulator receiver domain protein (CheY-like) YP_749186.1 KEGG: cps:CPS_0652 hypothetical protein YP_749187.1 KEGG: sde:Sde_3701 hypothetical protein YP_749188.1 KEGG: cps:CPS_4285 acetyltransferase, GNAT family YP_749189.1 PFAM: FAD dependent oxidoreductase; KEGG: cps:CPS_1461 putative oxidoreductase YP_749190.1 PFAM: Na+/H+ antiporter NhaC; KEGG: pha:PSHAa1677 Na+/H+ antiporter NnaC YP_749191.1 KEGG: son:SO0439 hypothetical protein YP_749192.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_749193.1 involved in de novo purine biosynthesis YP_749194.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_749195.1 PFAM: permease; KEGG: son:SO0444 hypothetical protein YP_749197.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0523 transcriptional regulator, LysR family YP_749198.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO0524 HlyD family secretion protein YP_749199.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0525 drug resistance transporter, EmrB/QacA family protein YP_749200.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0526 acetyltransferase, GNAT family YP_749201.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0527 hypothetical protein YP_749202.1 PFAM: porin, Gram-negative type; KEGG: son:SO3896 outer membrane porin, putative YP_749203.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: son:SO3895 HesA/MoeB/ThiF family protein YP_749204.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO3894 sensor histidine kinase YP_749205.1 KEGG: son:SO3892 hypothetical protein YP_749206.1 KEGG: ppr:PBPRA2831 conserved hypothetical protein YP_749207.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; 4-vinyl reductase, 4VR; SMART: AAA ATPase; KEGG: gme:Gmet_2116 transcriptional regulator, fis family YP_749208.1 KEGG: son:SO3056 tetraheme cytochrome c YP_749209.1 KEGG: ilo:IL2008 secreted protein of porin family YP_749210.1 KEGG: dsy:DSY2606 putative fumarate reductase flavoprotein subunit; TIGRFAM: Twin-arginine translocation pathway signal; flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase YP_749212.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: son:SO3800 serine protease, subtilase family YP_749213.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_749214.1 PFAM: pseudouridine synthase; KEGG: hch:HCH_04661 pseudouridylate synthases, 23S RNA-specific YP_749215.1 KEGG: son:SO0973 hypothetical protein YP_749216.1 KEGG: son:SO0971 hypothetical protein YP_749217.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO0968 D-lactate dehydrogenase YP_749218.1 PFAM: dienelactone hydrolase; KEGG: pha:PSHAa2188 hydrolase YP_749219.1 KEGG: son:SO0961 hypothetical protein YP_749220.1 KEGG: son:SO0960 hypothetical spermidine synthase YP_749221.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO0958 alkyl hydroperoxide reductase, C subunit YP_749222.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0956 alkyl hydroperoxide reductase, F subunit YP_749223.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: hch:HCH_06069 methyl-accepting chemotaxis protein YP_749224.1 KEGG: son:SO4008 hypothetical protein YP_749225.1 KEGG: son:SO4007 hypothetical protein YP_749226.1 KEGG: son:SO4006 hypothetical protein YP_749227.1 KEGG: son:SO4005 hypothetical protein YP_749228.1 PFAM: sodium:dicarboxylate symporter; KEGG: son:SO4004 proton/glutamate symporter, putative YP_749230.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_749231.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: son:SO3990 dipeptidyl peptidase IV YP_749232.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO3988 aerobic respiration control protein ArcA YP_749233.1 KEGG: son:SO3987 hypothetical protein YP_749234.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_749235.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO3985 hypothetical protein YP_749236.1 PFAM: peptidase M50; KEGG: son:SO0823 hypothetical protein YP_749237.1 KEGG: son:SO0824 hypothetical protein YP_749238.1 PFAM: protein of unknown function DUF342; KEGG: son:SO0826 hypothetical protein YP_749239.1 PFAM: methyltransferase small; Methyltransferase small, N-terminal domain protein; KEGG: son:SO0828 ribosomal RNA small subunit methyltransferase C YP_749240.1 PFAM: Alkaline phosphatase; KEGG: son:SO0830 alkaline phosphatase YP_749241.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_749242.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_749243.1 PFAM: Endonuclease I; KEGG: son:SO0833 endonuclease I YP_749244.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: son:SO0834 sprT protein, putative YP_749245.1 KEGG: son:SO0835 hypothetical protein YP_749246.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0839 transcriptional regulator, LysR family YP_749247.1 PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO0840 acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase YP_749248.1 KEGG: son:SO0841 GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein, family 3 YP_749249.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_749250.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0843 transcriptional regulator, LysR family YP_749251.1 KEGG: son:SO0845 cytochrome c-type protein NapB YP_749252.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_749253.1 KEGG: son:SO0855 hypothetical protein YP_749254.1 PFAM: protein of unknown function DUF214; KEGG: son:SO0856 putative ABC transport system permease protein YP_749255.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0857 ABC transporter, ATP-binding protein YP_749256.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: son:SO0861 hypothetical protein YP_749257.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_749258.1 KEGG: son:SO0863 hypothetical protein YP_749259.1 PFAM: regulatory protein, LuxR; KEGG: son:SO0864 transcriptional regulator, LuxR family YP_749260.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: son:SO1068 hypothetical protein YP_749261.1 KEGG: son:SO1069 hypothetical protein YP_749262.1 PFAM: Catalase domain protein; KEGG: son:SO1070 catalase YP_749263.1 PFAM: adenylate cyclase; KEGG: son:SO3769 hypothetical protein YP_749264.1 PFAM: protein of unknown function DUF47; KEGG: son:SO3770 conserved hypothetical protein TIGR00153 YP_749265.1 PFAM: phosphate transporter; KEGG: son:SO3771 phosphate transporter, putative YP_749266.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: son:SO3772 SH3 domain protein YP_749267.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_749268.1 KEGG: vpa:VPA0120 hypothetical protein YP_749269.1 PFAM: Na+/H+ antiporter NhaC; KEGG: son:SO1087 Na+/H+ antiporter family protein YP_749270.1 KEGG: son:SO1086 hypothetical protein YP_749271.1 TIGRFAM: Pseudouridine synthase, Rsu; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pha:PSHAa0085 ribosomal RNA pseudouridylate synthase YP_749272.1 KEGG: son:SO1075 hypothetical protein YP_749273.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: son:SO1074 tyrosine-specific transport protein, putative YP_749274.1 PFAM: protein of unknown function UPF0016; KEGG: son:SO1071 hypothetical protein YP_749275.1 KEGG: pha:PSHAb0212 hypothetical protein YP_749276.1 KEGG: son:SO0974 hypothetical protein YP_749277.1 PFAM: regulatory protein, MarR; KEGG: son:SO0977 transcriptional regulator, MarR family YP_749278.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_749279.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: son:SO0986 chromate transporter, putative YP_749280.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: son:SO0987 methyl-accepting chemotaxis protein YP_749281.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: cps:CPS_4083 peptide chain release factor 2, programmed frameshift YP_749282.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_749283.1 PFAM: thioesterase superfamily protein; KEGG: vpa:VPA0775 hypothetical protein YP_749284.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: vch:VCA0644 NADH oxidase, putative YP_749285.1 PFAM: ferric-uptake regulator; KEGG: aci:ACIAD0910 negative regulator of ferric iron uptake YP_749286.1 PFAM: protein of unknown function DUF134; KEGG: ppr:PBPRB1238 putative DNA-binding protein YP_749287.1 SMART: WD-40 repeat protein; KEGG: cps:CPS_0436 hypothetical protein YP_749288.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_749289.1 KEGG: cps:CPS_1933 sensory box/GGDEF/EAL domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_749290.1 KEGG: son:SO4593 hypothetical protein YP_749291.1 PFAM: peptidase S41; KEGG: pha:PSHAa0289 hypothetical protein YP_749292.1 KEGG: pha:PSHAa0288 hypothetical protein YP_749293.1 PFAM: OmpA/MotB domain protein; KEGG: hch:HCH_04311 outer membrane protein and related peptidoglycan-associated (LipO)protein YP_749294.1 PFAM: protein of unknown function UPF0126; KEGG: son:SO3342 hypothetical protein YP_749299.1 KEGG: ilo:IL0291 hypothetical protein YP_749300.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2; KEGG: vpa:VPA1447 putative transcriptional regulator, LuxR family YP_749301.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_749302.1 PFAM: protein of unknown function DUF72; KEGG: ppr:PBPRA1111 hypothetical protein YP_749303.1 KEGG: pfo:Pfl_4564 hypothetical protein YP_749304.1 KEGG: ilo:IL0121 hypothetical protein YP_749305.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1049 acetyltransferase, GNAT family YP_749306.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO3388 ATP-dependent RNA helicase, DEAD box family YP_749307.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: protein of unknown function DUF839; KEGG: son:SO2385 hypothetical protein YP_749308.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vch:VCA0890 glyoxylase I family protein YP_749309.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rpa:RPA3480 putative outer membrane receptor for iron transport YP_749310.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: aci:ACIAD0531 putative hydroxylase YP_749311.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4568 formate-dependent nitrite reductase, nrfD protein YP_749312.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: vfi:VF1552 thiosulfate reductase electron transport subunit YP_749313.1 KEGG: eca:ECA1876 cytochrome C-type protein YP_749315.1 PFAM: regulatory protein, LysR; KEGG: son:SO4571 transcriptional regulator, LysR family YP_749316.1 PFAM: Mg2 transporter protein, CorA family protein; KEGG: son:SO3984 magnesium transporter, putative YP_749317.1 PFAM: Uncharacterised conserved protein UCP006287; KEGG: son:SO3983 hypothetical protein YP_749318.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO3982 DNA-binding nitrate/nitrite response regulator YP_749319.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: son:SO3981 nitrate/nitrite sensor protein NarQ YP_749320.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_749321.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO0761 nitrogen regulatory protein P-II 1 YP_749322.1 PFAM: Rh family protein/ammonium transporter; KEGG: son:SO0760 ammonium transporter YP_749323.1 KEGG: son:SO0758 hypothetical protein YP_749324.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0757 TPR domain protein YP_749325.1 KEGG: mag:amb0186 ABC-type amino acid transport/signal transduction systems YP_749326.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_749327.1 KEGG: son:SO0755 hypothetical protein YP_749328.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0754 ABC transporter, ATP-binding protein YP_749329.1 KEGG: son:SO0753 hypothetical protein YP_749330.1 KEGG: son:SO0752 hypothetical protein YP_749331.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: son:SO0750 glutamate synthase, putative YP_749332.1 KEGG: son:SO0748 hypothetical protein YP_749333.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO0747 ferredoxin--NADP reductase YP_749334.1 PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO0744 iron(III) ABC transporter, periplasmic iron(III)-binding protein YP_749335.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO0743 iron(III) ABC transporter, permease protein YP_749336.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: son:SO0742 iron(III) ABC transporter, ATP-binding protein YP_749337.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: son:SO0740 melanin biosynthesis protein TyrA, putative YP_749338.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_749339.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: son:SO0923 hypothetical protein YP_749340.1 KEGG: son:SO0924 hypothetical protein YP_749341.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0926 acetyltransferase, GNAT family YP_749342.1 KEGG: son:SO0927 hypothetical protein YP_749343.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vch:VC0317 hypothetical protein YP_749344.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_749345.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_749346.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_749347.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_749348.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_749349.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: plu:plu0798 hypothetical protein YP_749350.1 PFAM: protein of unknown function DUF481; KEGG: son:SO0934 hypothetical protein YP_749351.1 KEGG: son:SO0940 transcriptional regulator-related protein YP_749353.1 KEGG: son:SO0942 hypothetical protein YP_749354.1 KEGG: son:SO0943 sensory box protein, putative YP_749355.1 PFAM: Radical SAM domain protein; KEGG: son:SO0944 hypothetical protein YP_749356.1 PFAM: acriflavin resistance protein; KEGG: son:SO0945 AcrB/AcrD/AcrF family protein YP_749357.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SO0946 hypothetical protein YP_749358.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_749359.1 PFAM: methyltransferase small; KEGG: son:SO0948 hypothetical protein YP_749360.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: son:SO0949 branched-chain amino acid transport system II carrier protein BrnQ YP_749361.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO0950 integrase/recombinase XerD YP_749362.1 KEGG: son:SO0951 thiol:disulfide interchange protein DsbC YP_749363.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: son:SO0952 single-stranded-DNA-specific exonuclease RecJ YP_749364.1 KEGG: son:SO3580 putative lipoprotein YP_749365.1 KEGG: pha:PSHAa0933 pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_749366.1 PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726 YP_749367.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: son:SO3577 clpB protein YP_749368.1 KEGG: son:SO3576 hypothetical protein YP_749369.1 KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_749370.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_749371.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_749372.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_749373.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_749374.1 PFAM: porin, Gram-negative type; KEGG: cps:CPS_3847 porin YP_749375.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_749376.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_749377.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_749378.1 TIGRFAM: anaerobic c4-dicarboxylate antiporter, Dcu family; PFAM: anaerobic c4-dicarboxylate membrane transporter; KEGG: vfi:VF2354 anaerobic C4-dicarboxylate transporter YP_749379.1 catalyzes the formation of fumarate from aspartate YP_749380.1 KEGG: vpa:VPA0374 periplasmic L-asparaginase II; TIGRFAM: L-asparaginases, type II; PFAM: Asparaginase/glutaminase YP_749381.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_749382.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_749383.1 KEGG: vpa:VP1880 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_749384.1 PFAM: aromatic amino acid permease; KEGG: vpa:VP1879 serine transporter YP_749385.1 PFAM: YheO domain protein; KEGG: vvy:VV1021 hypothetical protein YP_749386.1 KEGG: son:SO1159 hypothetical protein YP_749387.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; FR47 domain protein; KEGG: son:SO1160 ribosomal-protein-alanine acetyltransferase YP_749388.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_749389.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_749390.1 PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein YP_749391.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase YP_749392.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: son:SO1165 rare lipoprotein A YP_749393.1 TIGRFAM: lytic murein transglycosylase B; KEGG: son:SO1166 membrane-bound lytic transglycosylase, putative YP_749394.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: son:SO1167 rod shape-determining protein RodA YP_749395.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: son:SO1168 penicillin-binding protein 2 YP_749396.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_749397.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: son:SO1170 iojap domain protein YP_749398.1 KEGG: son:SO1171 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_749399.1 KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_749400.1 PFAM: Rare lipoprotein B; KEGG: son:SO1173 rare lipoprotein B YP_749401.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_749402.1 PFAM: protein of unknown function DUF1451; KEGG: son:SO1175 hypothetical protein YP_749404.1 PFAM: methylation site containing protein; KEGG: son:SO1176 hypothetical protein YP_749405.1 Transfers the fatty acyl group on membrane lipoproteins YP_749406.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: son:SO1178 magnesium and cobalt efflux protein CorC YP_749407.1 PFAM: protein of unknown function UPF0054; KEGG: son:SO1179 conserved hypothetical protein TIGR00043 YP_749408.1 PFAM: PhoH family protein; KEGG: son:SO1180 PhoH family protein YP_749409.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_749411.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; KEGG: son:SO1183 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_749412.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_749413.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_749414.1 PFAM: Patatin; KEGG: pha:PSHAb0541 putative hydrolase similar to YjjU YP_749415.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_749416.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_749417.1 PFAM: outer membrane lipoprotein LolB; KEGG: son:SO3835 outer membrane lipoprotein LolB YP_749418.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_749419.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_749420.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Methyltransferase type 12; KEGG: son:SO3832 hemK family protein YP_749421.1 PFAM: Invasion gene expression up-regulator, SirB; KEGG: son:SO3830 hypothetical protein YP_749422.1 KEGG: son:SO3829 hypothetical protein YP_749423.1 PFAM: protein of unknown function DUF819; KEGG: son:SO3828 hypothetical protein YP_749424.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_749425.1 KEGG: son:SO3822 hypothetical protein YP_749426.1 KEGG: son:SO3817 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_749427.1 PFAM: VanZ family protein; KEGG: son:SO3816 hypothetical protein YP_749428.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_749429.1 KEGG: son:SO0792 hypothetical protein YP_749430.1 PFAM: OmpA domain protein transmembrane region-containing protein; KEGG: vpa:VP0636 putative outer membrane protein A YP_749431.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: ppr:PBPRB0036 putative Cold shock-like protein YP_749432.1 KEGG: son:SO0793 hypothetical protein YP_749433.1 KEGG: bbr:BB0920 hypothetical protein YP_749434.1 TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: cps:CPS_1756 hypothetical protein YP_749435.1 KEGG: mhu:Mhun_2822 spore coat assembly protein-like YP_749437.1 KEGG: ppr:PBPRB1083 hypothetical protein YP_749438.1 PFAM: Rh family protein/ammonium transporter; KEGG: ppr:PBPRB0379 putative ammonium permease YP_749439.1 KEGG: cps:CPS_0669 lipid-transfer protein YP_749440.1 KEGG: par:Psyc_1394 hypothetical protein YP_749441.1 PFAM: DSBA oxidoreductase; KEGG: pst:PSPTO4177 2-hydroxychromene-2-carboxylate isomerase family protein YP_749442.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA1964 putative molybdopterin oxidoreductase YP_749443.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD; KEGG: pfo:Pfl_0280 formate dehydrogenase, subunit FdhD YP_749444.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VPA0961 putative transcriptional regulator YP_749445.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO1850 DnaJ domain protein YP_749446.1 KEGG: son:SO1849 hypothetical protein YP_749447.1 KEGG: son:SO1848 hypothetical protein YP_749448.1 KEGG: son:SO1846 hypothetical protein YP_749449.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_749450.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_749451.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: nwi:Nwi_1214 glyoxalase/bleomycin resistance protein/dioxygenase YP_749452.1 PFAM: sodium:dicarboxylate symporter; KEGG: oih:OB1282 H(+):sodium-glutamate symporter YP_749453.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pha:PSHAa2647 conserved protein of unknown function with GGDEF domain YP_749454.1 PFAM: NUDIX hydrolase; KEGG: ppr:PBPRB0617 putative MutT/NUDIX family protein YP_749455.1 KEGG: ppr:PBPRA3144 putative pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_749456.1 TIGRFAM: gamma-glutamyl phosphate reductase; KEGG: pha:PSHAa0280 gamma-glutamyl phosphate reductase YP_749457.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_749458.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: cps:CPS_3463 proline/sodium symporter YP_749459.1 PFAM: regulatory protein, TetR; KEGG: psb:Psyr_2754 regulatory protein, TetR YP_749460.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: psb:Psyr_2753 zinc-containing alcohol dehydrogenase superfamily YP_749461.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO1500 sensory box protein YP_749462.1 KEGG: gme:Gmet_1668 putative transmembrane protein YP_749463.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: gme:Gmet_1669 TonB-dependent receptor, plug YP_749464.1 KEGG: ppr:PBPRB1424 hypothetical protein YP_749465.1 PFAM: peptidase S45, penicillin amidase; KEGG: son:SO0918 aculeacin A acylase YP_749466.1 PFAM: carbon starvation protein CstA; KEGG: pha:PSHAb0210 cold-shock regulated carbon starvation protein A YP_749467.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4404 iron-sulfur cluster-binding protein YP_749468.1 KEGG: son:SO1975 zinc carboxypeptidase-related protein YP_749469.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO1976 hydrolase, alpha/beta fold family YP_749470.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vvy:VVA0252 transcriptional regulator YP_749471.1 PFAM: deoxyribodipyrimidine photolyase-related protein; KEGG: son:SO4169 hypothetical protein YP_749472.1 KEGG: csa:Csal_0772 hypothetical protein YP_749473.1 PFAM: DNA photolyase, FAD-binding; KEGG: pha:PSHAa2200 deoxyribodipyrimidine photolyase YP_749474.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: son:SO0768 putative NADH-flavin reductase YP_749475.1 PFAM: KAP P-loop domain protein; KEGG: sar:SAR1897 hypothetical protein YP_749476.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VP2378 transcriptional regulator, LysR family YP_749477.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: vch:VC2323 hypothetical protein YP_749478.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: ilo:IL0308 hypothetical protein YP_749479.1 KEGG: son:SO3571 hypothetical protein YP_749480.1 PFAM: pseudouridine synthase; KEGG: cps:CPS_3679 RNA pseudouridine synthase family protein YP_749481.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_749482.1 PFAM: sulfotransferase; KEGG: rru:Rru_A1463 sulfotransferase YP_749483.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: vfi:VFA1052 sulfate transporter YP_749484.1 PFAM: UspA domain protein; KEGG: plt:Plut_0944 UspA-related nucleotide-binding protein YP_749485.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO0988 formate dehydrogenase, alpha subunit YP_749486.1 PFAM: protein of unknown function DUF541; KEGG: son:SO4070 hypothetical protein YP_749487.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: reu:Reut_A1003 regulatory protein, LysR:LysR, substrate-binding YP_749488.1 PFAM: class II aldolase/adducin family protein; KEGG: rso:RSc1767 hypothetical protein YP_749489.1 PFAM: Bile acid:sodium symporter; KEGG: syn:sll1428 P3 protein YP_749490.1 KEGG: son:SO1695 sensory box/GGDEF family protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: PAS domain containing protein YP_749491.1 KEGG: son:SO1698 hypothetical protein YP_749492.1 PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO1699 transcriptional regulator YP_749493.1 PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein; KEGG: bja:bll0134 2-dehydropantoate 2-reductase YP_749494.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: cps:CPS_1348 putative Xaa-Pro dipeptidase YP_749495.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: syf:Synpcc7942_1811 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor YP_749496.1 PFAM: regulatory protein, MarR; KEGG: pae:PA2849 probable transcriptional regulator YP_749497.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: vpa:VPA1416 putative oxidoreductase YP_749498.1 PFAM: ThiJ/PfpI domain protein; KEGG: psp:PSPPH_3239 ThiJ/PfpI family protein YP_749499.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: pha:PSHAb0122 putative glutathione S-transferase YP_749500.1 KEGG: cps:CPS_1725 hypothetical protein YP_749501.1 KEGG: son:SO3722 hypothetical protein YP_749502.1 PFAM: major facilitator superfamily MFS_1; KEGG: sde:Sde_0120 transporter, MFS superfamily YP_749503.1 KEGG: cps:CPS_0693 hypothetical protein YP_749504.1 KEGG: cps:CPS_0694 putative lipoprotein YP_749505.1 PFAM: protein of unknown function DUF1111; KEGG: cps:CPS_0695 putative lipoprotein YP_749506.1 KEGG: son:SO3720 protoporphyrinogen oxidase YP_749507.1 KEGG: son:SO3719 hypothetical protein YP_749508.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_4921 substrate-binding transcriptional regulator, LysR family YP_749509.1 PFAM: aldo/keto reductase; KEGG: pha:PSHAa0541 oxidoreductase, aldo/keto reductase YP_749510.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: cps:CPS_0985 putative alpha amylase YP_749511.1 PFAM: DSBA oxidoreductase; KEGG: son:SO3718 thiol:disulfide interchange protein, DsbA family YP_749512.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO3716 DnaJ domain protein YP_749513.1 KEGG: son:SO0807 hypoxanthine-guanine phosphoribosyltransferase YP_749514.1 PFAM: peptidase U32; KEGG: son:SO3797 peptidase, U32 family YP_749515.1 KEGG: son:SO0808 hypothetical protein YP_749517.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO0815 TonB-dependent receptor C-terminal domain protein YP_749518.1 KEGG: son:SO0816 hypothetical protein YP_749519.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0817 transcriptional activator protein MetR YP_749520.1 PFAM: protein of unknown function DUF1458; KEGG: rso:RS05065 hypothetical protein YP_749521.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: son:SO3861 iron-sulfur cluster-binding protein YP_749522.1 KEGG: cps:CPS_0629 GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_749523.1 KEGG: son:SO3856 hypothetical protein YP_749524.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_749525.1 PFAM: protein of unknown function DUF1456; KEGG: son:SO3852 hypothetical protein YP_749526.1 KEGG: vpa:VP2681 putative manganese transporter YP_749527.1 PFAM: membrane-flanked domain; KEGG: son:SO3849 hypothetical protein YP_749528.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAa0840 TonB-dependent receptor YP_749529.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: sme:SMb20420 putative glutathione S-transferase protein YP_749530.1 KEGG: son:SO3848 hypothetical protein YP_749531.1 KEGG: son:SO3847 hypothetical protein YP_749532.1 KEGG: son:SO3846 hypothetical protein YP_749533.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: son:SO3844 peptidase, M13 family YP_749534.1 TIGRFAM: Pseudouridine synthase, Rsu; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ssn:SSO_2239 16S pseudouridylate 516 synthase YP_749535.1 KEGG: son:SO3842 hypothetical protein YP_749536.1 KEGG: son:SO3841 hypothetical protein YP_749537.1 PFAM: sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO3840 RNA polymerase sigma-70 factor, ECF subfamily YP_749538.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3838 methyl-accepting chemotaxis protein YP_749539.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_749540.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pca:Pcar_2715 small-conductance mechanosensitive channel YP_749541.1 KEGG: pca:Pcar_2714 hypothetical protein YP_749542.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_749543.1 KEGG: ilo:IL0065 predicted transcription negative regulator YP_749544.1 PFAM: Negative transcriptional regulator; KEGG: gka:GK0739 transcriptional repressor of sporulation and degradative enzyme production YP_749545.1 PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_1258 putative MFS transporter family protein YP_749546.1 KEGG: vfi:VFA0727 hypothetical cytosolic protein YP_749547.1 PFAM: methylation site containing protein; KEGG: son:SO3781 hypothetical protein YP_749548.1 KEGG: nmu:Nmul_A1768 hypothetical protein YP_749549.1 PFAM: cytochrome c, class I; KEGG: pae:PA4619 probable C-type cytochrome YP_749550.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: bur:Bcep18194_B1542 (2Fe-2S)-binding protein YP_749551.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: pfo:Pfl_1905 twin-arginine translocation pathway signal YP_749552.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3582 methyl-accepting chemotaxis protein YP_749553.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: son:SO1708 4-hydroxybutyrate coenzyme A transferase YP_749555.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: sde:Sde_3077 response regulator receiver domain protein (CheY-like) YP_749556.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_749557.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_749558.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: son:SO0452 thioredoxin 2 YP_749559.1 KEGG: vch:VCA0425 hypothetical protein YP_749560.1 KEGG: ppr:PBPRA1069 hypothetical protein YP_749561.1 PFAM: lipase, class 3; KEGG: vvy:VVA0214 predicted lipase YP_749562.1 KEGG: ppr:PBPRA1068 hypothetical protein YP_749563.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_749564.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO1031 alpha-ribazole-5'-phosphate phosphatase, putative YP_749565.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1033 iron-compound ABC transporter, ATP-binding protein, putative YP_749566.1 PFAM: transport system permease protein; KEGG: son:SO1034 iron-compound ABC transporter, permease protein YP_749567.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_749568.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_749569.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: son:SO1037 cobinamide kinase/cobinamide phosphate guanylyltransferase YP_749570.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_749571.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_749572.1 SMART: extracellular solute-binding protein, family 3; KEGG: hch:HCH_00910 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_749573.1 PFAM: helix-turn-helix, HxlR type; KEGG: cps:CPS_1319 transcriptional regulator YP_749574.1 PFAM: aldehyde dehydrogenase; KEGG: cps:CPS_1321 aldehyde dehydrogenase (NAD) family protein YP_749575.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: cps:CPS_1322 oxidoreductase, 2OG-Fe(II) oxygenase family YP_749577.1 PFAM: pseudouridine synthase; KEGG: vfi:VFA0485 ribosomal large subunit pseudouridine synthase A YP_749578.1 PFAM: beta-lactamase domain protein; KEGG: bce:BC3440 beta-lactamase, type II YP_749579.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRB0453 hypothetical protein YP_749580.1 PFAM: ABC-1 domain protein; KEGG: vpa:VPA1239 putative ABC transporter YP_749581.1 PFAM: sulfotransferase; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: eli:ELI_00455 TPR domain protein YP_749582.1 PFAM: SEC-C motif domain protein; Aspartyl/Asparaginyl beta-hydroxylase; KEGG: cps:CPS_4429 aspartyl/asparaginyl beta-hydroxylase family protein YP_749583.1 PFAM: sulfotransferase; SEC-C motif domain protein; KEGG: tbd:Tbd_0299 hypothetical protein YP_749584.1 PFAM: isochorismatase hydrolase; KEGG: son:SO0762 isochorismatase family protein YP_749585.1 KEGG: son:SO3711 hypothetical protein YP_749586.1 PFAM: periplasmic binding protein; KEGG: son:SO3709 ABC transporter, periplasmic substrate-binding protein, putative YP_749587.1 KEGG: sec:SC147 hypothetical protein YP_749588.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SO3694 HlyD family secretion protein YP_749589.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3692 ABC transporter, ATP-binding protein YP_749590.1 PFAM: protein of unknown function DUF214; KEGG: xcv:XCV3757 ABC transporter permease YP_749591.1 PFAM: protein of unknown function DUF214; KEGG: son:SO3690 ABC transporter, permease protein YP_749592.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: son:SO3689 sigma-54 dependent nitrogen response regulator YP_749593.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3688 nitrogen regulation protein NtrY, putative YP_749594.1 KEGG: cps:CPS_3405 hypothetical protein YP_749595.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: cps:CPS_3406 hypothetical protein YP_749596.1 KEGG: cps:CPS_3407 putative lipoprotein YP_749597.1 KEGG: son:SO3708 hypothetical protein YP_749598.1 KEGG: son:SO3591 hypothetical protein YP_749599.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: vpa:VP2915 hypothetical protein YP_749600.1 KEGG: son:SO3587 hypothetical protein YP_749601.1 KEGG: pha:PSHAa2038 uridylyltransferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase, beta domain protein region; metal-dependent phosphohydrolase, HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase, HD region YP_749602.1 TIGRFAM: Pseudouridine synthase, Rsu; PFAM: pseudouridine synthase; KEGG: cps:CPS_4413 putative ribosomal small subunit pseudouridine synthase A YP_749603.1 PFAM: regulatory protein, LysR; KEGG: son:SO1661 transcriptional regulator, LysR family YP_749604.1 KEGG: son:SO1659 decaheme cytochrome c YP_749605.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO1505 transporter, putative YP_749606.1 PFAM: SEC-C motif domain protein; KEGG: ppr:PBPRA1441 hypothetical protein YP_749607.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_749608.1 PFAM: DNA polymerase III chi subunit, HolC; KEGG: son:SO3423 DNA polymerase III, chi subunit YP_749609.1 KEGG: ilo:IL0309 hypothetical protein YP_749610.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pfo:Pfl_4320 transcriptional regulator, LysR family YP_749611.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hch:HCH_02025 short-chain alcohol dehydrogenase-like protein YP_749612.1 SMART: extracellular solute-binding protein, family 3; KEGG: bba:Bd2855 putative ABC amino acid transporter solute binding protein YP_749613.1 uncharacterized member of the major facilitator superfamily (MFS) YP_749614.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2374 transcriptional regulator, LysR family YP_749615.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_749616.1 PFAM: permease YjgP/YjgQ family protein; KEGG: son:SO1369 hypothetical protein YP_749617.1 PFAM: permease YjgP/YjgQ family protein; KEGG: son:SO1370 hypothetical protein YP_749618.1 PFAM: RDD domain containing protein; KEGG: son:SO1371 hypothetical protein YP_749619.1 KEGG: son:SO1372 hypothetical protein YP_749620.1 PFAM: protein of unknown function DUF486; KEGG: son:SO1373 hypothetical protein YP_749621.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1374 acetyltransferase, GNAT family YP_749622.1 KEGG: eli:ELI_10435 hypothetical protein YP_749623.1 KEGG: hch:HCH_04001 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_749624.1 KEGG: son:SO1380 hypothetical protein YP_749625.1 KEGG: son:SO3597 hypothetical protein YP_749626.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO3596 hypothetical protein YP_749627.1 PFAM: regulatory protein, TetR; KEGG: son:SO3684 transcriptional regulator, TetR family YP_749628.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO3683 coniferyl aldehyde dehydrogenase YP_749629.1 PFAM: UspA domain protein; KEGG: son:SO3681 universal stress protein family YP_749630.1 PFAM: protein of unknown function DUF924; KEGG: ilo:IL1577 hypothetical protein YP_749631.1 PFAM: membrane-flanked domain; KEGG: sde:Sde_3047 serine/threonine protein kinase YP_749632.1 PFAM: membrane-flanked domain; KEGG: sde:Sde_3048 hypothetical protein YP_749633.1 KEGG: son:SO3679 hypothetical protein YP_749634.1 PFAM: Mg2 transporter protein, CorA family protein; KEGG: bsu:BG12913 similar to divalent cation transport protein YP_749635.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: son:SO1098 hypothetical alkylated DNA repair protein YP_749636.1 PFAM: BolA family protein; KEGG: son:SO1099 bolA protein YP_749637.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: son:SO1100 extracellular solute-binding protein, family 7 YP_749638.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_749639.1 KEGG: son:SO1102 TonB-dependent receptor C-terminal region domain lipoprotein YP_749640.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_749641.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_749642.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_749643.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_749644.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_749645.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_749646.1 PFAM: ApbE family lipoprotein; KEGG: son:SO1109 thiamin biosynthesis lipoprotein ApbE YP_749647.1 PFAM: protein of unknown function DUF539; KEGG: son:SO1110 hypothetical protein YP_749648.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: son:SO1111 bacterioferritin subunit 2 YP_749649.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: son:SO1112 bacterioferritin subunit 1 YP_749650.1 KEGG: ppr:PBPRA2528 hypothetical protein YP_749651.1 PFAM: Ankyrin; KEGG: ppr:PBPRA2368 hypothetical protein YP_749652.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_749653.1 KEGG: son:SO1115 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_749654.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: son:SO1117 cytosol aminopeptidase, putative YP_749656.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: son:SO1120 xanthine/uracil permease family protein YP_749657.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_749658.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_749659.1 KEGG: son:SO1123 hypothetical protein YP_749660.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_749661.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_749662.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO1136 ATP-dependent RNA helicase, DEAD box family YP_749663.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO1137 hypothetical protein YP_749664.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1139 peptidyl-prolyl cis-trans isomerase FklB YP_749665.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_749666.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_749667.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_749668.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: son:SO1191 transcription elongation factor GreA YP_749669.1 KEGG: ppr:PBPRB0499 hypothetical protein YP_749670.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_749671.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_749672.1 PFAM: protein of unknown function UPF0044; KEGG: son:SO1195 putative RNA-binding protein containing KH domain YP_749673.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_749674.1 KEGG: son:SO1197 cell division protein FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_749675.1 KEGG: son:SO1198 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_749676.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_749677.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_749678.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: son:SO1201 preprotein translocase, SecG subunit YP_749679.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_749680.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_749681.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_749682.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_749683.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_749684.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_749685.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO1208 GGDEF domain protein YP_749686.1 KEGG: son:SO1209 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_749687.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_749688.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_749690.1 PFAM: TatD-related deoxyribonuclease; KEGG: son:SO1213 hydrolase, TatD family YP_749691.1 TIGRFAM: nucleoside transporter; PFAM: Na dependent nucleoside transporter; nucleoside recognition domain protein; Na dependent nucleoside transporter domain protein; KEGG: son:SO1214 NupC family protein YP_749692.1 PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: son:SO1215 outer membrane protein OmpK, putative YP_749693.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_749694.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_749695.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_749696.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_749697.1 KEGG: son:SO1222 membrane protein YP_749698.1 KEGG: son:SO1223 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_749699.1 KEGG: son:SO1224 hypothetical protein YP_749700.1 PFAM: type IV pilus assembly PilZ; KEGG: son:SO1225 hypothetical protein YP_749701.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_749702.1 PFAM: type IV pilus assembly PilZ; KEGG: son:SO1227 hypothetical protein YP_749703.1 PFAM: nucleoside recognition domain protein; KEGG: son:SO1245 hypothetical protein YP_749704.1 PFAM: peptidase U32; KEGG: son:SO1248 hypothetical peptidase YP_749705.1 PFAM: peptidase U32; KEGG: son:SO1249 peptidase, U32 family YP_749706.1 KEGG: son:SO1250 hypothetical protein YP_749707.1 KEGG: son:SO1251 ferredoxin, 4Fe-4S YP_749708.1 KEGG: rfr:Rfer_1881 Ig-like, group 2 YP_749709.1 PFAM: Ig domain protein, group 2 domain protein; KEGG: lil:LA3075 surface protein Lk90-like protein YP_749710.1 KEGG: rfr:Rfer_3548 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_749711.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: gme:Gmet_2223 transcriptional regulator, NifA subfamily, fis family YP_749712.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1251 ferredoxin, 4Fe-4S YP_749713.1 PFAM: peptidase U32; KEGG: son:SO1252 peptidase, U32 family YP_749714.1 KEGG: son:SO1254 hypothetical protein YP_749715.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO1255 cyclic nucleotide phosphodiesterase, putative YP_749716.1 PFAM: thioesterase superfamily protein; KEGG: son:SO1256 hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_749717.1 KEGG: son:SO1260 hypothetical amino acid ABC transporter YP_749718.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; KEGG: bca:BCE5479 sensory box/GGDEF family protein YP_749719.1 PFAM: protein of unknown function DUF88; KEGG: son:SO3490 hypothetical protein YP_749720.1 PFAM: acriflavin resistance protein; KEGG: son:SO3484 AcrB/AcrD/AcrF family protein YP_749721.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3483 HlyD family secretion protein YP_749722.1 KEGG: ppr:PBPRA1873 hypothetical protein YP_749723.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_749724.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_749725.1 TIGRFAM: Ribonucleotide reductase regulator NrdR-like; PFAM: ATP-cone domain protein; KEGG: son:SO3470 ATP-cone domain protein YP_749726.1 KEGG: son:SO3469 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; Riboflavin-specific deaminase-like; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_749727.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_749728.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: son:SO3467 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II, putative YP_749729.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_749730.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_749731.1 KEGG: son:SO3464 thiamin-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_749732.1 PFAM: phosphatidylglycerophosphatase A; KEGG: son:SO3463 phosphatidylglycerophosphatase A YP_749733.1 KEGG: son:SO2460 hypothetical protein YP_749734.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: son:SO3462 DNA repair protein RecN YP_749735.1 PFAM: Auxin Efflux Carrier; KEGG: son:SO3461 transporter, putative YP_749736.1 KEGG: son:SO3459 hypothetical protein YP_749737.1 PFAM: protein of unknown function DUF416; KEGG: son:SO3458 hypothetical protein YP_749738.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_749739.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_749740.1 KEGG: son:SO3455 GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_749741.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_749742.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_749743.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_749744.1 PFAM: Septum formation initiator; KEGG: son:SO3439 cell division protein FtsB YP_749745.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_749746.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_749747.1 PFAM: tRNA pseudouridine synthase D, TruD; KEGG: son:SO3436 tRNA pseudouridine synthase D YP_749748.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_749749.1 KEGG: son:SO3434 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_749750.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: son:SO3433 lipoprotein NlpD YP_749751.1 TIGRFAM: RNA polymerase sigma factor RpoS; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: son:SO3432 RNA polymerase sigma-38 factor YP_749752.1 This protein performs the mismatch recognition step during the DNA repair process YP_749753.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_749754.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_749755.1 affects carbohydrate metabolism; has regulatory role in many processes YP_749756.1 TIGRFAM: sodium pump decarboxylases, gamma subunit; PFAM: sodium pump decarboxylase, gamma subunit; KEGG: vvy:VV2800 oxaloacetate decarboxylase, gamma subunit YP_749757.1 catalyzes the formation of pyruvate from oxaloacetate YP_749758.1 KEGG: vpa:VP2543 oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_749759.1 KEGG: cps:CPS_3313 putative lipoprotein YP_749760.1 PFAM: sodium:dicarboxylate symporter; KEGG: son:SO3562 proton/glutamate symporter, putative YP_749761.1 KEGG: son:SO3561 hypothetical protein YP_749762.1 PFAM: peptidase M16 domain protein; KEGG: son:SO3560 peptidase, M16 family YP_749763.1 involved in the first step of glutathione biosynthesis YP_749764.1 KEGG: son:SO3558 hypothetical protein YP_749765.1 KEGG: son:SO3557 hypothetical protein YP_749766.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_749767.1 KEGG: son:SO3554 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_749768.1 PFAM: von Willebrand factor, type A; KEGG: son:SO3552 von Willebrand factor type A domain protein YP_749769.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO3551 RNA polymerase sigma-70 factor, ECF subfamily YP_749770.1 KEGG: son:SO3550 hypothetical protein YP_749771.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; KEGG: son:SO3411 protease, putative YP_749772.1 PFAM: OsmC family protein; KEGG: son:SO3409 OsmC/Ohr family protein YP_749774.1 PFAM: DSBA oxidoreductase; KEGG: ppr:PBPRB0337 hypothetical 2-hydroxychromene-2-carboxylateisomerase family protein YP_749775.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO3403 ribosomal subunit interface protein YP_749776.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cps:CPS_4684 GGDEF domain protein YP_749777.1 PFAM: protein of unknown function DUF28; KEGG: son:SO3401 hypothetical protein YP_749778.1 KEGG: son:SO3395 hypothetical protein YP_749779.1 PFAM: regulatory protein, TetR; KEGG: son:SO3393 transcriptional regulator, TetR family YP_749780.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ppr:PBPRB1366 putative NADH-dependent flavin oxidoreductase YP_749781.1 PFAM: protein kinase; leucine-rich repeat protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein, typical subtype; KEGG: son:SO4016 hypothetical protein YP_749782.1 KEGG: bte:BTH_II1256 thioredoxin YP_749783.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: cps:CPS_1298 alkylphosphonate utilization operon protein PhnA YP_749784.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: hhe:HH1827 hypothetical protein YP_749785.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_749786.1 PFAM: cyclase/dehydrase; KEGG: son:SO1474 hypothetical protein YP_749787.1 PFAM: protein of unknown function UPF0125; KEGG: son:SO1475 hypothetical protein YP_749788.1 PFAM: SmpA/OmlA domain protein; KEGG: son:SO1476 small protein A YP_749789.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO1478 methylase, putative YP_749790.1 KEGG: son:SO1479 hypothetical protein YP_749791.1 KEGG: son:SO1480 GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_749792.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_749793.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: son:SO1484 isocitrate lyase YP_749794.1 PFAM: GAF domain protein; KEGG: son:SO3337 hypothetical protein YP_749795.1 KEGG: son:SO3336 hypothetical protein YP_749796.1 PFAM: protein of unknown function DUF980; KEGG: son:SO3335 hypothetical protein YP_749797.1 KEGG: son:SO3332 transcriptional regulator, CopG family YP_749798.1 KEGG: son:SO3331 hypothetical protein YP_749799.1 KEGG: cps:CPS_4821 hypothetical protein YP_749800.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO3324 acetyltransferase, GNAT family YP_749801.1 KEGG: son:SO3325 NrfJ-related protein YP_749802.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: son:SO3317 5'-nucleotidase, putative YP_749803.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: son:SO3316 hypothetical protein YP_749804.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_749805.1 KEGG: son:SO3314 fimbrial biogenesis and twitching motility protein, putative; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_749806.1 KEGG: son:SO3313 hypothetical protein YP_749807.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_749808.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_749809.1 KEGG: son:SO3310 hypothetical protein YP_749810.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_749811.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_749812.1 KEGG: cps:CPS_0070 hypothetical protein YP_749814.1 PFAM: cytochrome B561; KEGG: bba:Bd1410 putative Ni,Fe-hydrogenase I cytochrome b subunit YP_749815.1 PFAM: Redoxin domain protein; KEGG: son:SO2100 thioredoxin family protein YP_749816.1 KEGG: son:SO2101 lipoprotein, putative YP_749817.1 KEGG: son:SO2102 hypothetical protein YP_749818.1 PFAM: ApbE family lipoprotein; KEGG: son:SO2103 ApbE family protein YP_749819.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2104 DNA-binding response regulator YgiX, putative YP_749820.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2105 sensor protein YgiY, putative YP_749821.1 KEGG: son:SO4649 hypothetical protein YP_749822.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4648 sensor histidine kinase YP_749823.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4647 DNA-binding response regulator YP_749824.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: son:SO4646 hypothetical protein YP_749825.1 KEGG: son:SO4645 hypothetical protein YP_749826.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: son:SO3969 OmpA family protein YP_749827.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_749828.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_749829.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_749830.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: son:SO3291 cytidine/deoxycytidylate deaminase family protein YP_749831.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_749832.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_749833.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: son:SO3286 cytochrome bd-I oxidase subunit I YP_749834.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II YP_749835.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: ppr:PBPRA2556 hypothetical protein YP_749836.1 KEGG: hch:HCH_03970 protein required for attachment to host cells YP_749837.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3282 methyl-accepting chemotaxis protein YP_749838.1 PFAM: acriflavin resistance protein; KEGG: son:SO3279 AcrB/AcrD/AcrF family protein YP_749839.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SO3278 hypothetical protein YP_749840.1 PFAM: regulatory protein, TetR; KEGG: son:SO3277 transcriptional regulator, TetR family YP_749841.1 KEGG: son:SO3276 hypothetical protein YP_749842.1 PFAM: protein of unknown function DUF400; KEGG: son:SO3256 hypothetical protein YP_749843.1 KEGG: son:SO3257 hypothetical protein YP_749844.1 KEGG: son:SO3258 hypothetical protein YP_749845.1 KEGG: son:SO3274 hypothetical protein YP_749846.1 KEGG: son:SO3275 hypothetical protein YP_749847.1 PFAM: FlgN family protein; KEGG: son:SO3255 flagellar biosynthetic protein FlgN YP_749848.1 PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: son:SO3254 negative regulator of flagellin synthesis FlgM YP_749849.1 required for the assembly of the flagellar basal body P-ring YP_749850.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO3252 chemotaxis protein CheV YP_749851.1 PFAM: MCP methyltransferase, CheR-type; KEGG: son:SO3251 chemotaxis protein methyltransferase CheR YP_749852.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_749853.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_749854.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_749855.1 the hook connects flagellar basal body to the flagellar filament YP_749856.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_749857.1 makes up the distal portion of the flagellar basal body rod YP_749858.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_749859.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_749860.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_749861.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: son:SO3239.3 hypothetical flagellar hook-associated protein YP_749862.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_749863.1 PFAM: flagellin domain protein; KEGG: pae:PA1092 flagellin type B YP_749864.1 PFAM: flagellin domain protein; KEGG: pae:PA1092 flagellin type B YP_749865.1 PFAM: flagellar protein FlaG protein; KEGG: son:SO3236 flagellin FlaG YP_749866.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: son:SO3235 flagellar hook-associated protein FliD YP_749867.1 KEGG: son:SO3234 hypothetical protein YP_749868.1 flagellin specific chaperone YP_749869.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase; KEGG: son:SO3232 flagellar regulatory protein A YP_749870.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: son:SO3231 flagellar regulatory protein B YP_749871.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: son:SO3230 flagellar regulatory protein C YP_749872.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: son:SO3229 flagellar hook-basal body complex protein FliE YP_749873.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_749874.1 One of three proteins involved in switching the direction of the flagellar rotation YP_749875.1 binds to and inhibits the function of flagella specific ATPase FliI YP_749876.1 involved in type III protein export during flagellum assembly YP_749877.1 TIGRFAM: flagellar export protein FliJ; KEGG: son:SO3224 flagellar protein FliJ YP_749878.1 PFAM: flagellar hook-length control protein; KEGG: son:SO3223 flagellar hook-length control protein FliK YP_749879.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_749880.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_749881.1 One of three proteins involved in switching the direction of the flagellar rotation YP_749882.1 PFAM: flagellar biosynthesis protein, FliO; KEGG: son:SO3219 flagellar protein FliO YP_749883.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_749884.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: son:SO3217 flagellar biosynthetic protein FliQ YP_749885.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_749886.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_749887.1 membrane protein involved in the flagellar export apparatus YP_749888.1 positive regulator of class III flagellar genes YP_749889.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO3211 flagellar biosynthetic protein FlhG YP_749890.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_749891.1 PFAM: response regulator receiver; KEGG: son:SO3209 chemotaxis protein CheY YP_749892.1 PFAM: Chemotaxis phosphatase, CheZ; KEGG: son:SO3208 chemotaxis protein CheZ YP_749893.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: son:SO3207 chemotaxis protein YP_749894.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_749895.1 KEGG: son:SO3205 hypothetical protein YP_749896.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO3204 ParA family protein YP_749897.1 PFAM: CheW domain protein; KEGG: son:SO3203 CheW domain protein YP_749898.1 PFAM: CheW domain protein; KEGG: son:SO3202 purine-binding chemotaxis protein CheW YP_749899.1 KEGG: son:SO3200 hypothetical protein YP_749900.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase YP_749901.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO1579 hypothetical protein YP_749902.1 PFAM: protein of unknown function DUF785; KEGG: ilo:IL0498 predicted aspartyl protease YP_749903.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: vfi:VF0658 ribosomal protein S6 modification protein YP_749904.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO1583 hypothetical protein YP_749905.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: ilo:IL0032 methyl-accepting chemotaxis protein (PAS/PAC and MSP doamins) YP_749906.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_4528 methyl-accepting chemotaxis protein YP_749907.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1585 fumarylacetoacetate hydrolase family protein YP_749908.1 KEGG: son:SO1588 hypothetical protein YP_749909.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: son:SO1597 hypothetical protein YP_749910.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: son:SO1599 multi-domain beta-ketoacyl synthase YP_749911.1 KEGG: ppr:PBPRA1459 omega-3 polyunsaturated fatty acid synthase PfaB YP_749912.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KEGG: ppr:PBPRA1460 omega-3 polyunsaturated fatty acid synthase PfaA YP_749913.1 KEGG: son:SO1603 transcriptional regulator, putative YP_749914.1 KEGG: sde:Sde_3560 hypothetical protein YP_749915.1 KEGG: sde:Sde_3561 sigma-70 factor YP_749916.1 KEGG: sde:Sde_3562 hypothetical protein YP_749917.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sde:Sde_3563 ATPase YP_749919.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: hch:HCH_02603 FOG: TPR repeat YP_749920.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: hch:HCH_02602 hypothetical protein YP_749921.1 KEGG: sde:Sde_3567 hypothetical protein YP_749922.1 KEGG: sde:Sde_3568 helix-turn-helix, AraC type YP_749923.1 KEGG: hch:HCH_02599 hypothetical protein YP_749924.1 KEGG: sde:Sde_3552 lipoprotein, putative YP_749925.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: hch:HCH_02597 thiol-disulfide isomerase and thioredoxins YP_749926.1 KEGG: hch:HCH_02596 hypothetical protein YP_749927.1 PFAM: protein of unknown function DUF1058; SH3, type 3 domain protein; KEGG: sde:Sde_3549 hypothetical protein YP_749928.1 KEGG: hch:HCH_02594 hypothetical protein YP_749929.1 KEGG: hch:HCH_02593 hypothetical protein YP_749930.1 KEGG: hch:HCH_02592 hypothetical protein YP_749931.1 TIGRFAM: Twin-arginine translocation pathway signal; KEGG: hch:HCH_02591 hypothetical protein YP_749932.1 KEGG: sty:HCM2.0093c hypothetical protein YP_749933.1 KEGG: sty:STY3192 hypothetical protein YP_749935.1 PFAM: ApbE family lipoprotein; KEGG: sde:Sde_3569 membrane protein YP_749936.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: son:SO1604 4'-phosphopantetheinyl transferase family protein YP_749937.1 PFAM: beta-lactamase domain protein; KEGG: son:SO1606 metallo-beta-lactamase superfamily protein YP_749938.1 PFAM: regulatory protein, LysR; KEGG: son:SO1607 transcriptional regulator, LysR family YP_749939.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_749940.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_749941.1 KEGG: son:SO4019 hypothetical protein YP_749942.1 KEGG: son:SO1610 hypothetical protein YP_749943.1 KEGG: son:SO1611 hypothetical protein YP_749944.1 KEGG: son:SO1612 hypothetical protein YP_749945.1 KEGG: pha:PSHAa1976 hypothetical protein YP_749946.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1614 acetyltransferase, GNAT family YP_749947.1 KEGG: son:SO1615 hypothetical protein YP_749948.1 PFAM: Semialdehyde dehydrogenase, NAD - binding; oxidoreductase domain protein; Oxidoreductase, C-terminal domain protein; KEGG: yps:YPTB2178 putative oxidoreductase YP_749950.1 KEGG: son:SO1617 hypothetical protein YP_749951.1 KEGG: son:SO1618 hypothetical protein YP_749952.1 PFAM: protein of unknown function DUF446; KEGG: son:SO1619 hypothetical protein YP_749953.1 PFAM: pseudouridine synthase; KEGG: vfi:VF0613 tRNA pseudouridine synthase C YP_749954.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_749955.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: son:SO1623 PTS system, glucose-specific IIBC component YP_749956.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_749957.1 PFAM: CBS domain containing protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: mag:amb0553 response regulator YP_749958.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_749959.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_749960.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_749961.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_749962.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_749963.1 Catalyzes the phosphorylation of UMP to UDP YP_749964.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_749965.1 KEGG: son:SO1633 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_749966.1 PFAM: phosphatidate cytidylyltransferase; KEGG: son:SO1634 phosphatidate cytidylyltransferase YP_749967.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_749968.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: son:SO1636 membrane-associated zinc metalloprotease, putative YP_749969.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: son:SO1637 bacterial surface antigen YP_749970.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: son:SO1638 outer membrane protein OmpH YP_749971.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_749972.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_749973.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_749974.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_749975.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_749976.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_749977.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; tRNA(Ile)-lysidine synthetase-like; PFAM: PP-loop domain protein; KEGG: son:SO1645 cell cycle protein MesJ YP_749978.1 PFAM: peptidase M28; KEGG: son:SO2198 hypothetical aminopeptidase YP_749980.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: sde:Sde_3077 response regulator receiver domain protein (CheY-like) YP_749981.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvu:VV11783 acetyltransferase YP_749982.1 PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: vch:VC2333 ribosomal protein S6 modification protein-related protein YP_749983.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO1646 GGDEF family protein YP_749984.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: son:SO1647 glutathione-regulated potassium-efflux system protein KefB, putative YP_749985.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pha:PSHAb0332 putative RNA polymerase sigma factor YP_749986.1 KEGG: pha:PSHAb0331 hypothetical protein YP_749987.1 KEGG: pha:PSHAb0330 conserved protein of unknown function; putative secreted protein YP_749988.1 KEGG: pha:PSHAb0329 putative unknown lipoprotein YP_749989.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: pha:PSHAb0328 putative orphan protein; putative signal peptide YP_749990.1 KEGG: pha:PSHAb0327 hypothetical protein YP_749991.1 PFAM: SNF2-related protein; helicase domain protein; zinc finger, SWIM domain protein; SMART: DEAD/DEAH box helicase domain protein; KEGG: son:SO1651 Snf2 family protein YP_749992.1 KEGG: pha:PSHAb0422 putative orphan protein YP_749993.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_749994.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_749995.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: dsy:DSY3515 hypothetical protein YP_749996.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: syn:slr1627 hypothetical protein YP_749997.1 PFAM: DTW domain containing protein; KEGG: cps:CPS_2423 hypothetical protein YP_749998.1 PFAM: glycoside hydrolase, family 3 domain protein; PA14 domain protein; KEGG: sde:Sde_2674 ribosome-binding factor A YP_749999.1 KEGG: sde:Sde_1104 hypothetical protein YP_750000.1 PFAM: FAD dependent oxidoreductase; tryptophan halogenase; KEGG: sde:Sde_1104 hypothetical protein YP_750001.1 SMART: transcription factor jumonji, jmjC domain protein; KEGG: sde:Sde_2829 PASs1-related protein YP_750002.1 PFAM: SapC family protein; KEGG: sde:Sde_2830 SapC related protein YP_750003.1 PFAM: tryptophan halogenase; KEGG: cps:CPS_3699 putative tryptophan halogenase YP_750004.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: xcv:XCV4138 TonB-dependent outer membrane receptor YP_750005.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cps:CPS_3709 galactose operon repressor YP_750006.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_3732 sugar:cation symporter family protein YP_750007.1 PFAM: glycoside hydrolase, family 1; KEGG: cps:CPS_3706 beta-glucosidase YP_750008.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_3705 glucose/galactose transporter family protein YP_750009.1 PFAM: glycoside hydrolase, family 3 domain protein; KEGG: sde:Sde_0245 beta-glucosidase YP_750010.1 PFAM: glycoside hydrolase, family 16; KEGG: vvy:VVA0140 beta-glucanase YP_750011.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: son:SO1655 cysQ protein YP_750012.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_750013.1 PFAM: protein of unknown function DUF218; KEGG: son:SO1657 hypothetical protein YP_750014.1 KEGG: son:SO1658 hypothetical protein YP_750015.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: son:SO0883 hypothetical protein YP_750016.1 PFAM: protein of unknown function DUF583; KEGG: son:SO1662 hypothetical Ccm2-related protein YP_750017.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1663 ferredoxin-type protein NapF YP_750018.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: son:SO1664 UDP-glucose 4-epimerase YP_750019.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_750020.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_750021.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: PAS domain containing protein; AAA ATPase; KEGG: son:SO1669 transcriptional regulatory protein TyrR YP_750022.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1670 fumarylacetoacetate hydrolase family protein YP_750023.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain protein; KEGG: son:SO1671 glutathione S-transferase family protein YP_750024.1 PFAM: protein of unknown function DUF925; KEGG: son:SO1672 hypothetical protein YP_750025.1 receptor for colicin S4 YP_750026.1 KEGG: son:SO1674 short chain dehydrogenase family protein YP_750027.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_750028.1 KEGG: bba:Bd3766 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_750029.1 KEGG: son:SO1677 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_750030.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: son:SO1678 methylmalonate-semialdehyde dehydrogenase YP_750031.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal; KEGG: son:SO1679 acyl-CoA dehydrogenase family protein YP_750032.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_750033.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: son:SO1681 enoyl-CoA hydratase/isomerase family protein YP_750034.1 KEGG: son:SO1682 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_750035.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_750036.1 KEGG: son:SO1685 hypothetical protein YP_750037.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: pha:PSHAa1329 hypothetical protein YP_750038.1 KEGG: vpa:VPA0405 hypothetical protein YP_750040.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1690 ABC transporter, ATP-binding protein YP_750041.1 KEGG: son:SO1702 hypothetical protein YP_750042.1 PFAM: alpha/beta hydrolase fold; KEGG: cgb:cg1295 predicted hydrolase or acyltransferase (alpha/beta hydrolase superfamily) YP_750043.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: cps:CPS_1937 methyl-accepting chemotaxis protein YP_750044.1 PFAM: protein of unknown function DUF1415; KEGG: son:SO1715 hypothetical protein YP_750045.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO1716 transporter, LysE family YP_750046.1 KEGG: son:SO1718 hypothetical protein YP_750047.1 PFAM: amino acid-binding ACT domain protein; KEGG: son:SO1722 ACT domain protein YP_750048.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1723 phosphate ABC transporter, permease protein, putative YP_750049.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1724 phosphate ABC transporter, permease protein, putative YP_750050.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_750051.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_750052.1 KEGG: son:SO1736 hypothetical protein YP_750053.1 SMART: HNH nuclease; KEGG: son:SO1738 hypothetical protein YP_750054.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO1739 hypothetical protein YP_750055.1 KEGG: son:SO1741 hypothetical protein YP_750056.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_750057.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO1743 hydrolase, alpha/beta hydrolase fold family YP_750058.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_750059.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: ppr:PBPRA1465 steroid dehydrogenase YP_750060.1 KEGG: son:SO1812 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_750062.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: pha:PSHAa1795 hypothetical protein YP_750063.1 KEGG: pha:PSHAa1794 hypothetical protein YP_750064.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: ppr:PBPRA2675 putative nucleotide sugar dehydrogenase YP_750065.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: ppr:PBPRA0207 putative nucleotide sugar epimerase YP_750066.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: hch:HCH_04683 glycosyltransferase YP_750067.1 PFAM: glycosyl transferase, group 1; KEGG: pfo:Pfl_2819 glycosyl transferase, group 1 YP_750068.1 PFAM: glycosyl transferase, group 1; KEGG: hch:HCH_04684 glycosyltransferase YP_750069.1 KEGG: pfo:Pfl_2821 O-antigen polymerase YP_750070.1 PFAM: glycosyl transferase, family 2; KEGG: pfo:Pfl_2822 glycosyl transferase, family 2 YP_750071.1 PFAM: polysaccharide biosynthesis protein; KEGG: pfo:Pfl_2823 polysaccharide biosynthesis protein YP_750072.1 PFAM: sugar transferase; KEGG: pha:PSHAa1783 UDP-glucose lipid carrier transferase YP_750073.1 KEGG: pha:PSHAa1782 hypothetical protein YP_750074.1 PFAM: polysaccharide export protein; KEGG: pha:PSHAa1781 polysaccharide export-related protein YP_750075.1 PFAM: lipopolysaccharide biosynthesis; KEGG: pha:PSHAa1780 exopolysaccharide biosynthesis protein YP_750076.1 PFAM: PHP C-terminal domain protein; KEGG: pha:PSHAa1779 capsular polysaccharide biosynthesis, CapC YP_750077.1 KEGG: pha:PSHAa1778 hypothetical protein YP_750078.1 PFAM: O-antigen polymerase; KEGG: pha:PSHAa1797 hypothetical protein YP_750079.1 KEGG: ppr:PBPRA2674 putative UTP-glucose-1-phosphateuridylyltransferase, galU; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_750080.1 PFAM: FAD dependent oxidoreductase; KEGG: son:SO3073 hypothetical protein YP_750081.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO3072 3-oxoacyl-(acyl-carrier-protein) synthase I YP_750082.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO3071 erythronate-4-phosphate dehydrogenase YP_750083.1 KEGG: son:SO3070 aspartate semialdehyde dehydrogenese; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_750084.1 KEGG: son:SO3069 putative membrane protein YP_750085.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_750086.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3067 FolC bifunctional protein YP_750087.1 PFAM: Sporulation domain protein; KEGG: son:SO3066 DedD protein YP_750088.1 PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein YP_750089.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_750090.1 KEGG: cps:CPS_2668 conserved hypothetical protein YP_750091.1 decatenates replicating daughter chromosomes YP_750092.1 KEGG: pha:PSHAa1583 peptide methionine sulfoxide reductase MsrA 2 (protein-methionine-S-oxide reductase 2) (peptide Met(O) reductase 2); TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_750093.1 KEGG: cvi:CV3595 hypothetical protein YP_750094.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_1392 transcriptional regulator, LysR family YP_750095.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cps:CPS_1391 oxidoreductase, zinc-binding YP_750096.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: rba:RB1487 hypothetical protein YP_750097.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vpa:VPA0595 ATP-binding component of molybdate transport system YP_750098.1 PFAM: Redoxin domain protein; KEGG: tbd:Tbd_0156 hypothetical protein YP_750099.1 PFAM: nitroreductase; KEGG: pha:PSHAa1234 major NAD(P)H-flavin oxidoreductase YP_750100.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO3055 proline iminopeptidase YP_750101.1 PFAM: beta-lactamase domain protein; KEGG: son:SO3054 metallo-beta-lactamase family protein YP_750102.1 PFAM: protein of unknown function DUF182; KEGG: son:SO3051 hypothetical xanthine dehydrogenase accessory factor YP_750103.1 KEGG: son:SO3050 hypothetical protein YP_750104.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: son:SO3049 isoquinoline 1-oxidoreductase, alpha subunit, putative YP_750105.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: son:SO3048 isoquinoline 1-oxidoreductase, beta subunit, putative YP_750106.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vch:VCA0773 methyl-accepting chemotaxis protein YP_750107.1 KEGG: cps:CPS_0912 hypothetical protein YP_750108.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: cps:CPS_0913 sensory box sensor/GGDEF/EAL domain protein YP_750109.1 KEGG: cps:CPS_0914 hypothetical protein YP_750110.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_750111.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_750112.1 Involved in cell division; probably involved in intracellular septation YP_750113.1 KEGG: hch:HCH_00813 hypothetical protein YP_750114.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_750115.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_750116.1 Phosphoribosylanthranilate isomerase; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_750117.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_750118.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_750119.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_750120.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: son:SO3017 TrpH family protein YP_750121.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain protein; KEGG: son:SO3016 Sua5/YciO/YrdC/YwlC family protein YP_750122.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: son:SO3015 putative segregation and condensation protein A YP_750123.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: son:SO3014 putative segregation and condensation protein B YP_750124.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0701 transcriptional regulator, LysR family YP_750125.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRA2319 hypothetical membrane-fusion protein YP_750126.1 PFAM: acriflavin resistance protein; KEGG: ppr:PBPRA2318 hypothetical transporter, AcrB/D/F family YP_750127.1 TIGRFAM: Pseudouridine synthase, Rsu; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: eca:ECA2291 putative RNA pseudouridylate synthase YP_750129.1 PFAM: histone family protein DNA-binding protein; KEGG: son:SO1863 DNA-binding protein, HU family YP_750130.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: son:SO2109 hypothetical protein YP_750131.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; protein of unknown function DUF882; Peptidase M15A; KEGG: son:SO2110 hypothetical protein YP_750132.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_750133.1 PFAM: protein of unknown function DUF490; KEGG: son:SO2113 hypothetical protein YP_750134.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: son:SO2114 hypothetical protein YP_750135.1 PFAM: peptidase T2, asparaginase 2; KEGG: son:SO2115 asparaginase family protein YP_750136.1 PFAM: CBS domain containing protein; KEGG: son:SO2228 CBS domain protein YP_750137.1 KEGG: son:SO2229 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD/DEAH box helicase domain protein YP_750138.1 KEGG: son:SO2917 hypothetical protein YP_750139.1 KEGG: son:SO2650 hypothetical protein YP_750140.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_750141.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_750142.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_750143.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_750144.1 PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; KEGG: son:SO2757 membrane protein, putative YP_750145.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cps:CPS_3474 antioxidant, AhpC/Tsa family YP_750146.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_750147.1 PFAM: OmpA/MotB domain protein; KEGG: cps:CPS_3471 sodium-type flagellar protein MotY YP_750148.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: son:SO2752 conserved hypothetical protein TIGR00051 YP_750149.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO2751 MotA/TolQ/ExbB proton channel family protein YP_750150.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: son:SO2750 tolr protein YP_750151.1 PFAM: TolA family protein; KEGG: son:SO2749 tolA protein YP_750152.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_750153.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO2747 peptidoglycan-associated lipoprotein YP_750154.1 KEGG: son:SO2746 hypothetical protein YP_750155.1 KEGG: pha:PSHAa0696 hypothetical protein YP_750156.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_750157.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; KEGG: son:SO2744 helicase YP_750158.1 KEGG: cps:CPS_2494 hypothetical protein YP_750159.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_750160.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2742 sensor histidine kinase/response regulator YP_750161.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: pae:PA1655 probable glutathione S-transferase YP_750162.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ppr:PBPRA3127 putative lysine efflux permease YP_750163.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_750164.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_750165.1 KEGG: son:SO2740 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_750166.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aminotransferase, class I and II; aminotransferase class-III; KEGG: son:SO2739 8-amino-7-oxononanoate synthase YP_750167.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO2738 biotin synthesis protein BioC YP_750168.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_750169.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO2197 GGDEF family protein YP_750170.1 KEGG: son:SO2199 hypothetical protein YP_750171.1 PFAM: protein of unknown function DUF413; KEGG: son:SO2201 hypothetical protein YP_750172.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family YP_750173.1 PFAM: diacylglycerol kinase; KEGG: son:SO2203 diacylglycerol kinase YP_750174.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_750175.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: son:SO2208 phosphotyrosine protein phosphatase YP_750176.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_750177.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: son:SO2589 isopenicillin-N synthase YP_750178.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_750179.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: son:SO2785 ribonuclease E YP_750180.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sfx:S1170 pseudouridylate synthase YP_750181.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pha:PSHAa1814 phosphoglycolate phosphatase, contains a phosphatase-like domain YP_750182.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: vvy:VV1269 Maf-like protein YP_750183.1 PFAM: protein of unknown function DUF177; KEGG: son:SO2781 hypothetical protein YP_750184.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_750185.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_750186.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_750187.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: son:SO2777 malonyl CoA-acyl carrier protein transacylase YP_750188.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO2776 3-oxoacyl-[acyl-carrier protein] reductase YP_750189.1 carries the fatty acid chain in fatty acid biosynthesis YP_750190.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO2774 3-oxoacyl-(acyl-carrier-protein) synthase II YP_750191.1 PFAM: thioesterase superfamily protein; KEGG: son:SO2772 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_750192.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: son:SO2771 2-hydroxy-3-oxopropionate reductase YP_750193.1 KEGG: son:SO2727 cytochrome c3 YP_750194.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: vpa:VPA1065 putative nitrate reductase, large subunit protein YP_750195.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: vvy:VVA0956 uroporphyrinogen-III methylase YP_750196.1 PFAM: glycosyl transferase, family 3; KEGG: ppr:PBPRB0206 hypothetical protein YP_750197.1 PFAM: ANTAR domain protein; KEGG: tcx:Tcr_1151 response regulator receiver (CheY-like) and ANTAR domain protein YP_750198.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: vvu:VV20390 NAD(P)H-nitrite reductase YP_750199.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; KEGG: ppr:PBPRA1427 putative nitrite reductase (NAD(P)H) smallsubunit YP_750200.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_4950 nitrate permease YP_750201.1 PFAM: protein kinase; SMART: tyrosine protein kinase; protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: hch:HCH_05817 serine/threonine protein kinase YP_750202.1 PFAM: Curlin associated repeat protein; KEGG: bur:Bcep18194_B2589 hypothetical protein YP_750203.1 PFAM: Curlin associated repeat protein; KEGG: son:SO0865 hypothetical protein YP_750204.1 PFAM: Curlin associated repeat protein; KEGG: ppu:PP3398 curli fiber surface-exposed nucleator CsgB, putative YP_750205.1 PFAM: Curlin associated repeat protein; KEGG: pfo:Pfl_1996 curlin associated YP_750206.1 PFAM: regulatory protein, LuxR; KEGG: son:SO2725 transcriptional regulator, LuxR family YP_750207.1 KEGG: vfi:VF2407 CsgE-like protein YP_750208.1 KEGG: vfi:VF2406 curli production assembly/transport component CsgF precursor YP_750209.1 PFAM: Curli production assembly/transport component CsgG; KEGG: vfi:VF2405 curli production assembly/transport component CsgG precursor YP_750210.1 PFAM: peptidase M61 domain protein; KEGG: son:SO2724 protease, putative YP_750211.1 PFAM: histidine triad (HIT) protein; KEGG: son:SO2723 HIT family protein YP_750212.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: son:SO2722 hypothetical protein YP_750213.1 PFAM: thioesterase superfamily protein; KEGG: son:SO2721 hypothetical protein YP_750214.1 PFAM: protein of unknown function DUF1425; KEGG: son:SO2720 hypothetical protein YP_750215.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO2715 TonB-dependent receptor YP_750216.1 KEGG: son:SO2714 hypothetical protein YP_750217.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: son:SO2713 transporter, putative YP_750218.1 KEGG: son:SO2712 hypothetical protein YP_750219.1 KEGG: son:SO2711 hypothetical protein YP_750220.1 PFAM: DoxX family protein; KEGG: son:SO2710 hypothetical protein YP_750221.1 PFAM: nitroreductase; KEGG: son:SO2708 nitroreductase family protein YP_750222.1 KEGG: sdn:Sden_2314 hypothetical protein YP_750223.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain protein; KEGG: ppr:PBPRB1270 hypothetical protein YP_750224.1 PFAM: Rhodanese domain protein; KEGG: son:SO2290 rhodanese domain protein YP_750225.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ade:Adeh_3473 diguanylate cyclase (GGDEF domain) YP_750226.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_750227.1 molecular chaperone YP_750228.1 PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein YP_750229.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_750230.1 PFAM: PfkB domain protein; KEGG: son:SO2020 inosine-guanosine kinase YP_750231.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_750232.1 KEGG: son:SO2022 hypothetical protein YP_750233.1 KEGG: son:SO2024 hypothetical protein YP_750234.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cps:CPS_4941 sensory box/GGDEF domain protein YP_750235.1 KEGG: son:SO2858 hypothetical protein YP_750236.1 PFAM: Na+/solute symporter; KEGG: son:SO2857 sodium/solute symporter family protein YP_750237.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: son:SO2856 CBS domain protein YP_750238.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease YP_750239.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_750240.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: son:SO2852 transcriptional regulator, GntR family YP_750241.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_750242.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_750243.1 PFAM: Integrase, catalytic region; KEGG: pha:PSHAa0416 transposase YP_750244.1 PFAM: IstB domain protein ATP-binding protein; KEGG: pha:PSHAa0414 transposase YP_750245.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_750246.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_750247.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_750248.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_750249.1 PFAM: secretion protein HlyD family protein; KEGG: hch:HCH_01961 membrane-fusion protein YP_750250.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: dar:Daro_0987 ABC-2:ABC transporter related YP_750251.1 PFAM: ABC-2 type transporter; KEGG: sec:SC3514 putative ABC superfamily (atp_bind/membrane) transport protein YP_750252.1 KEGG: son:SO4012 hypothetical protein YP_750253.1 PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A YP_750254.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; KEGG: vpa:VPA0335 SoxR protein YP_750255.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO3586 glyoxalase family protein YP_750256.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_750257.1 putative metalloprotease YP_750258.1 KEGG: son:SO3389 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_750259.1 KEGG: rso:RSc3095 putative serine-rich protein YP_750261.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: pca:Pcar_0361 sensor histidine kinase YP_750262.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cps:CPS_3305 DNA-binding response regulator BaeR YP_750263.1 KEGG: son:SO2179 hypothetical protein YP_750264.1 PFAM: peptidase M23B; KEGG: son:SO2180 peptidase, M23/M37 family YP_750265.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: vvu:VV21212 hypothetical protein YP_750266.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppr:PBPRA2314 putative FAD-dependent dehydrogenase YP_750267.1 KEGG: gsu:GSU1169 hypothetical protein YP_750268.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_750269.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ppr:PBPRA2923 hypothetical protein YP_750270.1 KEGG: vfi:VF1779 tellurite resistance protein TehB YP_750271.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_750272.1 detoxifies nitric oxide using NADH YP_750273.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: hch:HCH_04858 transcriptional regulator YP_750274.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: hch:HCH_04860 permease of the major facilitator superfamily YP_750276.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvu:VV20941 histone acetyltransferase HPA2 YP_750277.1 PFAM: protein of unknown function DUF991; KEGG: son:SO2182 hypothetical protein YP_750278.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: son:SO2183 hypothetical protein YP_750279.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: sde:Sde_2579 hypothetical protein YP_750280.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1918 MATE efflux family protein YP_750281.1 KEGG: son:SO1921 hypothetical protein YP_750282.1 KEGG: son:SO2799 lipoprotein, putative YP_750283.1 PFAM: glutaredoxin; KEGG: son:SO2797 hypothetical protein YP_750284.1 PFAM: protein of unknown function DUF748; KEGG: son:SO2796 hypothetical protein YP_750285.1 KEGG: aci:ACIAD2379 putative acetyltransferase YP_750286.1 KEGG: son:SO2794 hypothetical protein YP_750287.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO2793 glyoxalase family protein YP_750288.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO2792 hypothetical protein YP_750289.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_2540 acetyltransferase, GNAT family YP_750290.1 PFAM: Integral membrane protein TerC; KEGG: hch:HCH_06655 membrane protein TerC, possibly involved in tellurium resistance YP_750291.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_750292.1 KEGG: cps:CPS_3135 hypothetical protein YP_750293.1 PFAM: peptidase M28; KEGG: son:SO2766 hypothetical protein YP_750294.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO2762 nagD protein YP_750295.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO2581 long-chain-fatty-acid--CoA ligase YP_750297.1 KEGG: vvy:VV1912 hypothetical protein YP_750298.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_750299.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_750300.1 KEGG: son:SO3714 sugar-binding protein, putative YP_750301.1 PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: pha:PSHAb0018 putative Zn-dependent enzyme YP_750302.1 PFAM: Glutathione S-transferase, N-terminal domain protein; KEGG: pha:PSHAb0017 putative glutathione S-transferase family protein YP_750303.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pha:PSHAb0014 putative transcriptional regulatory protein (LysR family) YP_750304.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_750305.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_750307.1 KEGG: son:SO1154 hypothetical protein YP_750310.1 catalyzes the formation of L-homocysteine from cystathionine YP_750311.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2192 sensor histidine kinase YP_750312.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2193 DNA-binding response regulator YP_750313.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO2194 OmpA family protein YP_750314.1 PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: son:SO2195 inter-alpha-trypsin inhibitor domain protein YP_750315.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: son:SO2196 LPXTG-site transpeptidase family protein YP_750316.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_750317.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: son:SO2279 acetolactate synthase large subunit YP_750318.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO2280 bicyclomycin resistance protein YP_750319.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: pha:PSHAa2458 sulfate permease protein YP_750320.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO3563 SM-20 domain protein YP_750321.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO2850 acetyltransferase, GNAT family YP_750322.1 KEGG: son:SO2848 hypothetical protein YP_750323.1 PFAM: Uncharacterised conserved protein UCP025560; KEGG: cps:CPS_4712 hypothetical protein YP_750324.1 KEGG: son:SO2063 hypothetical protein YP_750325.1 KEGG: son:SO2064 hypothetical protein YP_750326.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_750327.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_750328.1 PFAM: phage integrase family protein; KEGG: cps:CPS_2015 site-specific recombinase, phage integrase family YP_750329.1 KEGG: son:SO3007 hypothetical protein YP_750332.1 KEGG: son:SO2664 hypothetical protein YP_750335.1 KEGG: sao:SAOUHSC_00163 hypothetical protein YP_750336.1 KEGG: sao:SAOUHSC_00164 hypothetical protein YP_750337.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; KEGG: pae:PA0906 probable transcriptional regulator YP_750338.1 conserved in bacteria, prophage-related; KEGG: hch:HCH_00596 uncharacterized protein conserved in bacteria, prophage-related YP_750340.1 KEGG: son:SO2987 hypothetical protein YP_750341.1 KEGG: sdn:Sden_3264 hypothetical protein YP_750342.1 KEGG: hit:NTHI1724 hypothetical protein YP_750343.1 PFAM: replication P family protein; KEGG: hch:HCH_00598 hypothetical protein YP_750344.1 PFAM: phage integrase family protein; KEGG: vvy:VVA0857 phage integrase YP_750345.1 PFAM: helix-turn-helix domain protein; KEGG: sdn:Sden_3260 transciptional regulator YP_750347.1 PFAM: putative esterase; KEGG: cps:CPS_4960 putative esterase YP_750351.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: sde:Sde_3077 response regulator receiver domain protein (CheY-like) YP_750352.1 PFAM: protein of unknown function DUF1311; KEGG: rbe:RBE_0642 hypothetical protein YP_750354.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ppr:PBPRB0776 putative adenylate cyclase CyaB YP_750355.1 KEGG: ssn:SSO_1885 hypothetical bacteriophage protein YP_750360.1 PFAM: glycoside hydrolase, family 24; KEGG: son:SO0659 lysozyme, putative YP_750363.1 PFAM: phage DNA packaging Nu1; KEGG: ssn:SSO_2431 bacteriophage DNA packaging protein YP_750364.1 PFAM: phage terminase GpA; KEGG: ecs:ECs1630 terminase large subunit YP_750365.1 KEGG: ecs:ECs2962 hypothetical protein YP_750366.1 TIGRFAM: phage portal protein, lambda family; PFAM: phage portal protein, lambda; KEGG: stm:STM0911 hypothetical protein YP_750367.1 PFAM: peptidase S14, ClpP; KEGG: stm:STM0912 ATP-dependent protease YP_750368.1 KEGG: stm:STM1034 putative RecA/RadA recombinase YP_750372.1 KEGG: hch:HCH_02903 hypothetical protein YP_750373.1 TIGRFAM: phage tape measure protein; KEGG: son:SO0680 hypothetical protein YP_750375.1 KEGG: son:SO0682 hypothetical protein YP_750376.1 KEGG: son:SO0683 hypothetical protein YP_750378.1 KEGG: son:SO0688 hypothetical protein YP_750379.1 KEGG: sdn:Sden_3237 hypothetical protein YP_750380.1 KEGG: son:SO2789 hypothetical protein YP_750381.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_750382.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: son:SO2787 cold shock domain family protein YP_750383.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1865 ABC transporter, ATP-binding protein YP_750384.1 PFAM: ABC-2 type transporter; KEGG: son:SO1866 hypothetical protein YP_750385.1 PFAM: protein of unknown function DUF480; KEGG: son:SO1867 hypothetical protein YP_750386.1 KEGG: son:SO1868 hypothetical protein YP_750387.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_750388.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative YP_750390.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_750391.1 PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein YP_750392.1 PFAM: YceI family protein; KEGG: son:SO2893 hypothetical protein YP_750393.1 KEGG: son:SO2891 hypothetical protein YP_750394.1 PFAM: protein of unknown function DUF785; KEGG: vfi:VFA0277 hypothetical protein YP_750395.1 PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: son:SO1844 extracellular nuclease, putative YP_750396.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_750397.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_750398.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_750399.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_750400.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pha:PSHAa2182 mechanosensitive ion channel YP_750401.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_750402.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_750403.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_750404.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_750405.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_750406.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_750407.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_750408.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_750409.1 KEGG: pha:PSHAb0167 putative GGDEF sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_750410.1 KEGG: sde:Sde_0294 putative transcriptional regulator, fis family YP_750411.1 TIGRFAM: Twin-arginine translocation pathway signal; KEGG: cps:CPS_3489 hypothetical protein YP_750413.1 PFAM: permease; KEGG: cps:CPS_3357 putative permease YP_750414.1 KEGG: rpa:RPA3557 thiol-disulfide isomerase and thioredoxins YP_750415.1 SMART: helicase c2; KEGG: son:SO2081 ATP-dependent helicase, DinG family YP_750416.1 PFAM: peptidase M22, glycoprotease; KEGG: son:SO2586 hypothetical protein YP_750417.1 KEGG: son:SO2585 hypothetical protein YP_750418.1 KEGG: son:SO2584 hypothetical protein YP_750419.1 KEGG: son:SO2583 hypothetical protein YP_750420.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO2582 hydrolase, alpha/beta fold family YP_750421.1 Activates fatty acids by binding to coenzyme A YP_750422.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: son:SO2580 ribonuclease D YP_750423.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_750424.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO2577 septum site-determining protein MinD YP_750425.1 blocks the formation of polar Z-ring septums YP_750426.1 PFAM: protein of unknown function DUF709; KEGG: son:SO2575 hypothetical protein YP_750427.1 KEGG: ilo:IL1824 membrane-bound lytic murein transglycosylase YP_750428.1 PFAM: protein of unknown function UPF0153; KEGG: son:SO2573 hypothetical protein YP_750429.1 PFAM: Disulphide bond formation protein DsbB; KEGG: son:SO2887 disulfide bond formation protein b YP_750430.1 involved in regulation of intracellular pH under alkaline conditions YP_750431.1 Multifunctional regulator of fatty acid metabolism YP_750432.1 PFAM: SpoVR family protein; KEGG: son:SO2884 hypothetical protein YP_750433.1 PFAM: protein of unknown function DUF444; KEGG: son:SO2883 hypothetical protein YP_750434.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: son:SO2882 hypothetical Ser protein kinas YP_750435.1 PFAM: manganese and iron superoxide dismutase; KEGG: son:SO2881 superoxide dismutase, Fe YP_750436.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: son:SO2880 glutaredoxin domain protein YP_750437.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: son:SO2879 uracil permease YP_750438.1 KEGG: son:SO2878 hypothetical protein YP_750439.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_750440.1 KEGG: son:SO2876 hypothetical protein YP_750441.1 KEGG: son:SO2872 hypothetical protein YP_750442.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: son:SO2871 arsenate reductase, putative YP_750443.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO2869 hypothetical protein YP_750444.1 PFAM: SirA family protein; KEGG: son:SO2868 hypothetical protein YP_750445.1 PFAM: protein of unknown function UPF0118; KEGG: son:SO2867 permease PerM, putative YP_750446.1 KEGG: son:SO2479 hypothetical protein YP_750447.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_750448.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO2477 alcohol dehydrogenase, iron-containing YP_750449.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO2476 polysaccharide biosynthesis protein YP_750450.1 PFAM: carbonic anhydrase; KEGG: son:SO2474 carbonic anhydrase family protein YP_750451.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO2473 hydrolase, alpha/beta fold family YP_750452.1 PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: son:SO2472 D-alanyl-D-alanine carboxypeptidase-related protein YP_750453.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_750454.1 TIGRFAM: conserved hypothetical protein; PFAM: arsenate reductase and related; KEGG: son:SO2470 hypothetical protein YP_750455.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_750456.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: son:SO2237 phosphotransferase system, enzyme I YP_750457.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: son:SO2238 phosphocarrier protein HPr YP_750458.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO2240 methyl-accepting chemotaxis protein YP_750459.1 KEGG: son:SO2241 hypothetical protein YP_750460.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: son:SO2244 transcriptional regulator, LacI family YP_750461.1 PFAM: protein of unknown function DUF808; KEGG: son:SO1151 hypothetical protein YP_750462.1 PFAM: protein of unknown function DUF805; KEGG: stm:STM3234 putative inner membrane protein YP_750463.1 PFAM: glycoside hydrolase 15-related; KEGG: son:SO2459 glucoamylase YP_750464.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO2458 transporter, putative YP_750465.1 KEGG: son:SO2450 alpha-glucosidase YP_750466.1 PFAM: protein of unknown function DUF358; KEGG: ppr:PBPRA1526 hypothetical protein YP_750467.1 KEGG: cps:CPS_0256 hypothetical protein YP_750468.1 PFAM: proton/sugar symporter, LacY; major facilitator superfamily MFS_1; KEGG: pab:PAB0874 hypothetical protein YP_750469.1 PFAM: UspA domain protein; KEGG: mma:MM3222 hypothetical protein YP_750470.1 KEGG: rfr:Rfer_4032 hypothetical protein YP_750471.1 KEGG: eca:ECA2743 hypothetical protein YP_750472.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: son:SO2156 alpha amylase family protein YP_750473.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: pha:PSHAa1354 alpha-amylase YP_750474.1 PFAM: tryptophan halogenase; KEGG: pha:PSHAa1353 tryptophan halogenase YP_750475.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAa1352 TonB-dependent receptor protein YP_750476.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: son:SO2213 alpha-glucosidase YP_750477.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_3705 glucose/galactose transporter family protein YP_750478.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO2215 sun protein, putative YP_750479.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: son:SO2216 sensory box protein YP_750480.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: son:SO2216 sensory box protein YP_750481.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: pha:PSHAa1718 alanine dehydrogenase YP_750482.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_750483.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: son:SO2306 cell division protein FtsK, putative YP_750484.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: son:SO2307 outer membrane lipoprotein carrier protein LolA YP_750485.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO2308 ATPase, AAA family YP_750486.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_750487.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_750488.1 PFAM: DsrC family protein; KEGG: son:SO2379 putative sulfite reductase YP_750489.1 KEGG: son:SO2378 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_750490.1 PFAM: DsrE family protein; KEGG: son:SO2377 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_750491.1 PFAM: DsrE family protein; KEGG: son:SO2376 DsrE-related protein YP_750492.1 PFAM: protein of unknown function UPF0005; KEGG: son:SO2375 membrane protein, putative YP_750493.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2374 transcriptional regulator, LysR family YP_750494.1 KEGG: nmu:Nmul_A0181 hypothetical protein YP_750495.1 PFAM: ABC-1 domain protein; KEGG: xcb:XC_2511 ubiquinone biosynthesis protein YP_750496.1 PFAM: chemotaxis sensory transducer; KEGG: cps:CPS_4961 methyl-accepting chemotaxis protein YP_750497.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: vfi:VF2515 glycine betaine transporter YP_750498.1 3'-5' exonuclease of DNA polymerase III YP_750499.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: vfi:VF2513 cyclic nucleotide binding protein/2 CBS domains YP_750500.1 PFAM: protein of unknown function DUF214; KEGG: pca:Pcar_0817 hypothetical protein YP_750501.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tbd:Tbd_1413 ABC transporter ATPase YP_750502.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: tbd:Tbd_1414 secretion protein HlyD YP_750503.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: pha:PSHAa2878 curved DNA-binding protein, co-chaperone of DnaK (HSP40) YP_750504.1 KEGG: pha:PSHAa2877 hypothetical protein YP_750505.1 KEGG: dps:DP0206 probable glycine betaine/L-proline transport ATP-binding protein (ProV); TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_750506.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dps:DP0207 probable glycine betaine/L-proline transport system permease protein (ProW) YP_750507.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_750508.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_750509.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; KEGG: cac:CAC0490 predicted sugar kinase, N-terminal region - uncharacterized conserved protein YP_750510.1 KEGG: cps:CPS_1821 acyltransferase family protein YP_750511.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: cps:CPS_4619 HD domain protein YP_750512.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: ppu:PP1869 hypothetical protein YP_750513.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family YP_750514.1 PFAM: transmembrane pair domain protein; KEGG: cps:CPS_0422 hypothetical protein YP_750515.1 KEGG: cps:CPS_4709 hypothetical protein YP_750516.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: cps:CPS_3420 DNA-binding response regulator, LuxR family YP_750517.1 PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: cps:CPS_3419 sensory box sensor histidine kinase/response regulator YP_750518.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_3417 putative branched-chain amino acid ABC transporter, ATP-binding protein YP_750519.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cps:CPS_3416 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding YP_750520.1 PFAM: inner-membrane translocator; KEGG: cps:CPS_3415 putative branched-chain amino acid ABC transporter, permease protein YP_750521.1 PFAM: inner-membrane translocator; KEGG: cps:CPS_3414 putative branched-chain amino acid ABC transporter, permease protein YP_750522.1 KEGG: cps:CPS_3413 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein YP_750523.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_3412 putative branched chain amino acid ABC transporter, ATP-binding protein YP_750524.1 KEGG: cps:CPS_3411 putative phenylacetate-coenzyme A ligase YP_750525.1 PFAM: thioesterase superfamily protein; KEGG: cps:CPS_3410 hypothetical protein YP_750526.1 KEGG: vfi:VF1080 hypothetical protein YP_750527.1 PFAM: Ferritin, Dps family protein; KEGG: tcx:Tcr_1226 ferritin and Dps YP_750528.1 PFAM: regulatory protein, TetR; KEGG: vfi:VF1081 transcriptional regulator, TetR family YP_750529.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: pha:PSHAb0545 putative amino acid permease YP_750530.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4173 sensor histidine kinase YP_750531.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: son:SO4172 DNA-binding response regulator YP_750532.1 PFAM: transposase, IS4 family protein; KEGG: ret:RHE_CH01332 probable insertion sequence transposase protein, IS10 YP_750533.1 KEGG: ava:Ava_2971 WD-40 repeat YP_750534.1 KEGG: ana:all3488 unknown protein YP_750535.1 PFAM: protein of unknown function UPF0061; KEGG: pmt:PMT1392 conserved hypotheical protein YP_750536.1 KEGG: ilo:IL0571 hypothetical protein YP_750537.1 KEGG: pha:PSHAa1929 hypothetical protein YP_750538.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: son:SO1520 hypothetical protein YP_750539.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1519 iron-sulfur cluster-binding protein YP_750540.1 PFAM: protein of unknown function DUF162; KEGG: son:SO1518 hypothetical protein YP_750541.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3460 transcriptional regulator, LysR family YP_750542.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pha:PSHAa1776 transcriptional regulator YP_750543.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_750544.1 KEGG: cps:CPS_2821 putative 2-methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase YP_750545.1 Catalyzes the conversion of citrate to isocitrate YP_750546.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: pfo:Pfl_1767 protein of unknown function DUF453 YP_750547.1 PFAM: sodium/hydrogen exchanger; KEGG: son:SO2537 sodium/hydrogen exchanger family protein YP_750548.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_750549.1 KEGG: son:SO1878 glycine cleavage system transcriptional repressor, putative YP_750550.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_750551.1 PFAM: NlpBDapX family lipoprotein; KEGG: son:SO1880 lipoprotein-34 NlpB YP_750552.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO1881 HlyD family-related protein YP_750553.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: bur:Bcep18194_A4725 phenylacetic acid degradation-related protein YP_750554.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_750555.1 PFAM: glutamine amidotransferase, class-II; KEGG: son:SO2535 hypothetical amidotransferase YP_750556.1 KEGG: son:SO2533 hypothetical protein YP_750557.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: son:SO2532 methylated-DNA--protein-cysteine methyltransferase, putative YP_750558.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: son:SO2447 channel protein, hemolysin III family subfamily YP_750560.1 PFAM: Rhomboid family protein; KEGG: son:SO2504 hypothetical protein YP_750561.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: son:SO2503 ExsB protein YP_750562.1 KEGG: son:SO2501 radical activating enzyme YP_750563.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: vch:VC1061 cysteine synthase/cystathionine beta-synthase family protein YP_750564.1 KEGG: son:SO2500 hypothetical protein YP_750565.1 KEGG: hch:HCH_01260 hypothetical protein YP_750566.1 KEGG: son:SO2499 hypothetical protein YP_750567.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: son:SO2498 sensory box protein YP_750568.1 PFAM: SEC-C motif domain protein; KEGG: son:SO2497 conserved hypothetical protein YP_750569.1 KEGG: son:SO2495.1 hypothetical protein YP_750570.1 PFAM: Smr protein/MutS2; KEGG: son:SO2495 Smr domain protein YP_750571.1 PFAM: peptidase M2, peptidyl-dipeptidase A; KEGG: son:SO2494 zinc-dependent metallopeptidase YP_750572.1 PFAM: regulatory protein, TetR; KEGG: son:SO2493 transcriptional regulator, TetR family YP_750573.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_750574.1 PFAM: pyruvate kinase; KEGG: son:SO2491 pyruvate kinase II YP_750575.1 Represses the expression of the zwf, eda, glp and gap YP_750576.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_750577.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: son:SO2488 6-phosphogluconolactonase YP_750578.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_750579.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_750580.1 KEGG: son:SO4492 hypothetical protein YP_750581.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: dps:DP1920 hypothetical protein YP_750582.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: son:SO2136 aldehyde-alcohol dehydrogenase YP_750583.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pha:PSHAb0206 putative unknown enzyme YP_750584.1 PFAM: putative sugar-binding domain protein; KEGG: pha:PSHAa1504 transcriptional regulator YP_750585.1 KEGG: pha:PSHAb0207 putative nucleoside transport protein YP_750586.1 PFAM: transposase, IS4 family protein; KEGG: ret:RHE_CH01332 probable insertion sequence transposase protein, IS10 YP_750587.1 PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase rossman, N-terminal domain protein; KEGG: pha:PSHAb0208 D-mannonate oxidoreductase YP_750588.1 PFAM: PfkB domain protein; KEGG: pha:PSHAb0209 putative carbohydrate kinase YP_750589.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_750590.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO2484 hypothetical protein YP_750591.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_750592.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_750593.1 KEGG: son:SO2329 hypothetical protein YP_750594.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_750595.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: son:SO2331 hypothetical protein YP_750596.1 KEGG: son:SO2332 hypothetical protein YP_750597.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: son:SO2333 hydrolase, alpha/beta fold family YP_750598.1 negative modulator of the initiation of chromosome replication YP_750599.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_750600.1 KEGG: pha:PSHAa2581 hypothetical protein YP_750601.1 KEGG: son:SO4405 catalase/peroxidase HPI; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_750602.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: vpa:VPA0609 hypothetical protein YP_750603.1 KEGG: dar:Daro_1852 hypothetical protein YP_750604.1 KEGG: son:SO2394 penicillin-binding protein 4; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_750605.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_750606.1 PFAM: DTW domain containing protein; KEGG: son:SO2387 conserved hypothetical protein YP_750607.1 KEGG: son:SO2381 hypothetical protein YP_750608.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein YP_750609.1 KEGG: vfi:VF0709 hypothetical protein YP_750610.1 serine protease inhibitor, inhibits trypsin and other proteases YP_750611.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO2049 GGDEF family protein YP_750612.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: son:SO2116 acetyltransferase, GNAT family YP_750613.1 PFAM: acriflavin resistance protein; KEGG: cps:CPS_4483 AcrB/AcrD/AcrF family protein YP_750614.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: cps:CPS_4484 efflux transporter, RND family, MFP subunit subfamily YP_750615.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_0919 hypothetical protein YP_750616.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO2303 thioredoxin reductase YP_750617.1 KEGG: son:SO2337 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_750618.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_750619.1 PFAM: dehydrogenase, E1 component; KEGG: son:SO2339 alpha keto acid dehydrogenase complex, E1 component, alpha subunit YP_750620.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: son:SO2340 alpha keto acid dehydrogenase complex, E1 component, beta subunit YP_750621.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: son:SO2341 alpha keto acid dehydrogenase complex, E2 component YP_750622.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_750623.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO4053 methyl-accepting chemotaxis protein YP_750624.1 KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_750625.1 KEGG: son:SO2346 hypothetical protein YP_750626.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_750627.1 PFAM: regulatory protein, MarR; KEGG: cps:CPS_1337 transcriptional regulator, MarR family YP_750628.1 TIGRFAM: conserved hypothetical protein; KEGG: cps:CPS_4008 hypothetical protein YP_750629.1 KEGG: cps:CPS_1335 putative transporter, BCCT family protein YP_750630.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_750631.1 catalyzes the formation of betaine from betaine aldehyde YP_750632.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_750633.1 KEGG: cps:CPS_2680 hypothetical protein YP_750634.1 PFAM: phage integrase family protein; KEGG: cps:CPS_2062 site-specific recombinase, phage integrase family YP_750635.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: vvy:VV0273 hypothetical protein YP_750636.1 KEGG: vvy:VV0274 hypothetical protein YP_750637.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: plu:plu4319 type I site-specific deoxyribonuclease HsdM YP_750638.1 PFAM: restriction modification system DNA specificity domain; KEGG: hit:NTHI0315 putative type I restriction-modification system specificity protein YP_750639.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: tde:TDE2641 Fic family protein YP_750640.1 KEGG: plu:plu4322 type I site-specific deoxyribonuclease HsdR; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD/DEAH box helicase domain protein YP_750642.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: cps:CPS_1440 neutral zinc metallopeptidase, M13 family YP_750643.1 PFAM: protein of unknown function DUF330; KEGG: mca:MCA0364 lipoprotein, putative YP_750644.1 PFAM: Mammalian cell entry related domain protein; KEGG: dde:Dde_1983 putative paraquat-inducible protein B YP_750645.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dde:Dde_1984 ATPase YP_750646.1 PFAM: protein of unknown function DUF140; KEGG: dde:Dde_1985 ABC transporter permease protein YP_750647.1 PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein YP_750648.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein YP_750650.1 KEGG: son:SO4593 hypothetical protein YP_750651.1 KEGG: pha:PSHAa0302 hypothetical protein YP_750652.1 PFAM: protein of unknown function DUF411; KEGG: par:Psyc_1592 hypothetical protein YP_750653.1 TIGRFAM: Twin-arginine translocation pathway signal; copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: ppu:PP5380 copper resistance protein A YP_750654.1 PFAM: copper resistance B precursor; KEGG: tbd:Tbd_1325 probable copper resistance protein B YP_750655.1 PFAM: copper resistance protein CopC; KEGG: pha:PSHAb0009 putative copper resistance (CopC-like) YP_750656.1 PFAM: copper resistance D domain protein; KEGG: pha:PSHAb0008 putative copper export protein YP_750657.1 KEGG: pha:PSHAb0007 putative orphan protein YP_750658.1 KEGG: ppr:PBPRB1405 putative DNA-binding protein YP_750659.1 KEGG: vfi:VF1433 hypothetical protein YP_750660.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: cps:CPS_1875 sigma-54 dependent transcriptional regulator YP_750661.1 KEGG: cps:CPS_1881 hypothetical protein YP_750662.1 PFAM: beta-lactamase domain protein; KEGG: pmu:PM1479 hypothetical Synechosystis sp. YP_750663.1 PFAM: Rhodanese domain protein; KEGG: ilo:IL1695 rhodanese-related sulfurtransferase YP_750664.1 PFAM: protein of unknown function DUF81; KEGG: ttj:TTHA0835 conserved hypothetical membrane protein YP_750665.1 PFAM: beta-lactamase domain protein; KEGG: ilo:IL1442 Zn-dependent hydrolase, glyoxylase family YP_750666.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpb:RPB_4601 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_750667.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2409 transcriptional regulator, LysR family YP_750668.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: son:SO2408 radical activating enzyme YP_750669.1 KEGG: son:SO2407 hypothetical protein YP_750670.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tcx:Tcr_0379 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor YP_750671.1 PFAM: alpha/beta hydrolase fold; KEGG: bsu:BG12442 similar to hydrolase YP_750672.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: son:SO2564 transglycosylase, Slt family YP_750673.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO4694 hypothetical protein YP_750674.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_750675.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_750676.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: son:SO1230 sensor histidine kinase/response regulator TorS YP_750677.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_750678.1 TIGRFAM: Twin-arginine translocation pathway signal; trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: son:SO1232 trimethylamine-N-oxide reductase YP_750679.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO1233 tetraheme cytochrome c YP_750680.1 PFAM: periplasmic nitrate reductase NapE; KEGG: son:SO1234 warning TorE protein YP_750681.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO4157 DNA-binding response regulator YP_750682.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4155 sensor histidine kinase YP_750683.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO4062 polysulfide reductase, subunit A YP_750684.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4061 polysulfide reductase, subunit B YP_750685.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4060 polysulfide reductase, subunit C YP_750687.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: pha:PSHAa0258 regulator of nucleoside diphosphate kinase YP_750688.1 KEGG: vfi:VF1777 hypothetical protein YP_750690.1 PFAM: protein of unknown function DUF450; KEGG: ppr:PBPRA1804 putative type I restriction enzyme R protein YP_750691.1 PFAM: phage integrase family protein; KEGG: son:SO2370 site-specific recombinase, phage integrase family YP_750693.1 KEGG: son:SO2365 hypothetical protein YP_750694.1 CcoN; FixN YP_750695.1 CcoO; FixO YP_750696.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: son:SO2362 cytochrome c oxidase, cbb3-type, CcoQ subunit YP_750697.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: son:SO2361 cytochrome c oxidase, cbb3-type, subunit III YP_750698.1 KEGG: son:SO2360 hypothetical protein YP_750699.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: son:SO2359 cation transport ATPase, E1-E2 family YP_750700.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: son:SO2358 cytochrome oxidase maturation protein, cbb3-type YP_750701.1 KEGG: son:SO2357 hypothetical protein YP_750702.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_750703.1 with UspC and UspD is involved in resistance to UV irradiation YP_750704.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_750705.1 KEGG: son:SO2353 hypothetical protein YP_750706.1 PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; KEGG: son:SO2352 bax protein, putative YP_750707.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: son:SO2351 hypothetical protein YP_750708.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_750709.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_750710.1 PFAM: ribosomal protein L35; KEGG: son:SO2301 50S ribosomal protein L35 YP_750711.1 PFAM: initiation factor 3; KEGG: son:SO2300 translation initiation factor IF-3 YP_750712.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_750713.1 KEGG: son:SO2297 hypothetical protein YP_750714.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_750715.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO2295 MATE efflux family protein YP_750716.1 PFAM: aldehyde dehydrogenase; KEGG: bja:bll3998 probable succinate-semialdehyde dehydrogenase [NADP+] YP_750717.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: alcohol dehydrogenase, iron-containing YP_750718.1 KEGG: pha:PSHAa1766 hypothetical protein YP_750719.1 KEGG: tcx:Tcr_1936 hypothetical protein YP_750720.1 KEGG: tcx:Tcr_1933 uncharacterized conserved coiled coil protein YP_750721.1 KEGG: pha:PSHAb0310 hypothetical protein YP_750722.1 PFAM: protein of unknown function DUF885; KEGG: xcv:XCV4134 putative secreted protein YP_750723.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: cps:CPS_1177 acyl-CoA dehydrogenase family protein YP_750724.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: eli:ELI_09015 TonB-dependent receptor YP_750725.1 PFAM: nitroreductase; KEGG: tcx:Tcr_0408 nitroreductase YP_750726.1 PFAM: alpha/beta hydrolase fold; KEGG: rso:RSc1770 probable hydrolase protein YP_750727.1 KEGG: bja:bll1370 hypothetical protein YP_750728.1 PFAM: Bile acid:sodium symporter; KEGG: syn:sll1428 P3 protein YP_750729.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_750730.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ccr:CC0353 enoyl-CoA hydratase/isomerase family protein YP_750731.1 PFAM: alpha/beta hydrolase fold; KEGG: cps:CPS_4105 hypothetical protein YP_750732.1 KEGG: gsu:GSU0193 L-sorbosone dehydrogenase, putative YP_750733.1 KEGG: bfr:BF0537 hypothetical protein YP_750734.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_750735.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_750736.1 KEGG: vfi:VFA1144 hypothetical cytosolic protein YP_750737.1 PFAM: Integrase, catalytic region; KEGG: pha:PSHAa0416 transposase YP_750738.1 PFAM: IstB domain protein ATP-binding protein; KEGG: pha:PSHAa0414 transposase YP_750739.1 KEGG: bpm:BURPS1710b_0124 GDSL-like lipase/acylhydrolase domain protein YP_750740.1 PFAM: alpha/beta hydrolase fold; KEGG: ccr:CC1175 haloalkane dehalogenase, putative YP_750741.1 KEGG: pha:PSHAa0678 hypothetical protein YP_750742.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: pha:PSHAa0679 ATPase YP_750743.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sil:SPO1845 oxidoreductase, molybdopterin-binding YP_750744.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: ilo:IL0315 predicted NADP-dependent oxidoreductases YP_750745.1 KEGG: pha:PSHAb0546 hypothetical protein YP_750746.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cps:CPS_1189 long-chain-fatty-acid--CoA ligase YP_750747.1 KEGG: sma:SAV1384 putative acyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_750748.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ccr:CC2093 3-oxoacyl-(acyl-carrier-protein) reductase, putative YP_750749.1 PFAM: MaoC domain protein dehydratase; KEGG: eli:ELI_12095 MaoC domain protein YP_750750.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: psp:PSPPH_0495 acyl-CoA dehydrogenase family protein YP_750751.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bur:Bcep18194_B3036 short-chain dehydrogenase/reductase SDR YP_750752.1 PFAM: aminoglycoside phosphotransferase; KEGG: bur:Bcep18194_B3038 aminoglycoside phosphotransferase YP_750753.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal; KEGG: ppu:PP2437 acyl-CoA dehydrogenase, putative YP_750754.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: psb:Psyr_1011 NADH:flavin oxidoreductase/NADH oxidase YP_750755.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pfo:Pfl_3419 short-chain dehydrogenase/reductase SDR YP_750756.1 PFAM: Phosphoglycerate mutase; KEGG: aci:ACIAD1884 putative phosphoglycerate mutase related protein YP_750757.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rso:RSc2018 probable transcription regulator protein YP_750758.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; extracellular solute-binding protein, family 3; PAS fold-3 domain protein; PAS fold-4 domain protein; KEGG: gme:Gmet_3085 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) YP_750759.1 KEGG: son:SO4042 hydratase/decarboxylase family protein YP_750760.1 KEGG: ppr:PBPRA1435 hypothetical protein YP_750761.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO2525 ABC transporter, ATP-binding protein YP_750762.1 PFAM: peptidase U32; KEGG: ppr:PBPRA1758 putative collagenase family protease YP_750763.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAa2457 TonB-dependent receptor YP_750764.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: pha:PSHAa1750 tartronate semialdehyde reductase (TSAR) YP_750765.1 PFAM: protein of unknown function UPF0153; KEGG: cps:CPS_2168 conserved hypothetical protein YP_750767.1 KEGG: ava:Ava_B0313 hypothetical protein YP_750768.1 KEGG: ana:alr4914 unknown protein YP_750769.1 KEGG: ana:alr4911 unknown protein YP_750771.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase domain protein; KEGG: sma:SAV2928 DNA repair helicase YP_750772.1 PFAM: protein of unknown function DUF262; KEGG: hpj:jhp0462 hypothetical protein YP_750773.1 KEGG: eca:ECA2874 hypothetical protein YP_750774.1 KEGG: eca:ECA2875 putative ATP-binding protein YP_750775.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: eca:ECA2876 putative phage-related protein YP_750776.1 PFAM: aminotransferase, class V; KEGG: ecu:ECU11_1770 cysteine desulfurase YP_750777.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: pha:PSHAb0513 putative secreted hydrolase YP_750778.1 KEGG: son:SO2518 hypothetical protein YP_750779.1 PFAM: protein of unknown function DUF74; KEGG: cps:CPS_2458 hypothetical protein YP_750780.1 PFAM: protein of unknown function DUF302; KEGG: cps:CPS_2735 hypothetical protein YP_750781.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_0124 short chain dehydrogenase family protein YP_750782.1 KEGG: vpa:VPA0774 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_750783.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: vpa:VPA0773 N-ethylmaleimide reductase YP_750784.1 PFAM: MscS Mechanosensitive ion channel; KEGG: vpa:VPA1439 hypothetical protein YP_750786.1 KEGG: vfi:VF1324 hypothetical protein YP_750787.1 KEGG: son:SO2099 hydrogenase small chain; TIGRFAM: hydrogenase (NiFe) small subunit HydA; Twin-arginine translocation pathway signal; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_750788.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: son:SO2098 hydrogenase large chain YP_750789.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: son:SO2097 quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit YP_750790.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: son:SO2096 hydrogenase expression/formation protein YP_750791.1 KEGG: son:SO2095 hypothetical protein YP_750792.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain protein; zinc finger, HypF domain protein; KEGG: son:SO2094 hydrogenase maturation protein HypF YP_750793.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: son:SO2093 hydrogenase accessory protein HypB YP_750794.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF YP_750795.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: son:SO2091 hydrogenase expression/formation protein HypD YP_750796.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: son:SO2090 hydrogenase expression/formation protein HypE YP_750797.1 PFAM: hydrogenase expression/synthesis, HypA; KEGG: son:SO2089 hydrogenase expression/formation protein HypA YP_750799.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal; KEGG: son:SO2395 acyl-CoA dehydrogenase family protein YP_750800.1 KEGG: son:SO2517 hypothetical protein YP_750801.1 KEGG: son:SO2396 hypothetical protein YP_750802.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO2397 short chain dehydrogenase YP_750803.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_750804.1 KEGG: son:SO2399 hypothetical protein YP_750805.1 PFAM: protein of unknown function DUF1049; KEGG: son:SO2400 hypothetical protein YP_750806.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_750807.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_750808.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_750809.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_750810.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_750811.1 KEGG: son:SO0919 serine transporter, putative YP_750812.1 KEGG: son:SO2905 O-methyltransferase, putative YP_750813.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_750814.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; KEGG: son:SO2411 DNA gyrase subunit A YP_750815.1 Involved in ubiquinone biosynthesis YP_750816.1 KEGG: son:SO2414 phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_750817.1 Catalyzes the rate-limiting step in dNTP synthesis YP_750818.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_750819.1 PFAM: ferredoxin; KEGG: son:SO2417 iron-sulfur cluster-binding protein YP_750820.1 KEGG: pha:PSHAa0636 hypothetical protein YP_750821.1 KEGG: cps:CPS_3364 hypothetical protein YP_750822.1 KEGG: vpa:VP1356 hypothetical protein YP_750823.1 PFAM: protein of unknown function RIO1; KEGG: son:SO3973 RIO1/ZK632.3/MJ0444 family, putative YP_750824.1 PFAM: Calcium-binding EF-hand-containing protein; KEGG: tdn:Tmden_1322 hypothetical protein YP_750825.1 KEGG: hch:HCH_06678 hypothetical protein YP_750826.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ilo:IL1575 L-2-haloalkanoic acid dehalogenase, HAD superfamily YP_750827.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: vpa:VPA1298 putative glutathione S-transferase YP_750828.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO2419 2,4-dienoyl-CoA reductase, putative YP_750829.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: son:SO2420 signal peptide peptidase SppA, 67K type YP_750830.1 converts asparagine to aspartate and ammonia YP_750831.1 PFAM: protein of unknown function DUF1315; KEGG: son:SO2422 hypothetical protein YP_750832.1 KEGG: son:SO2423 hypothetical protein YP_750833.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: son:SO2424 zinc carboxypeptidase domain protein YP_750834.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2426 DNA-binding response regulator YP_750835.1 PFAM: protein of unknown function DUF885; KEGG: son:SO2570 lipoprotein, putative YP_750836.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_750837.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: vfi:VF1790 ATP-dependent RNA helicase YP_750838.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO2137 multiple antibiotic resistance protein YP_750839.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: son:SO2223 peptidase, putative YP_750840.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: son:SO2222 fumarate hydratase, class I, anaerobic, putative YP_750841.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: son:SO2221 para-aminobenzoate synthase, component I YP_750842.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: par:Psyc_0418 probable glutathione S-transferase YP_750843.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: son:SO1755 phosphoglucomutase/phosphomannomutase family protein YP_750844.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ilo:IL2271 outer membrane protein YP_750845.1 PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: son:SO1499 glycogen synthase YP_750846.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_750847.1 KEGG: son:SO1496 glycogen phosphorylase family protein; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_750848.1 KEGG: son:SO1495 glycogen operon protein; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_750849.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_750850.1 KEGG: son:SO1493 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_750851.1 PFAM: NUDIX hydrolase; KEGG: son:SO2220 MutT/nudix family protein YP_750852.1 KEGG: son:SO2219 hypothetical protein YP_750853.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_750854.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_750855.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO2507 GGDEF domain protein YP_750856.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: son:SO2508 RnfAE/NqrDE family protein YP_750857.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_750858.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_750859.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_750860.1 TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein; KEGG: son:SO2512 electron transport complex protein RnfG YP_750861.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_750862.1 KEGG: son:SO2514 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_750863.1 KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_750864.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_750865.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_750866.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_750867.1 PFAM: protein of unknown function DUF28; KEGG: son:SO2432 conserved hypothetical protein TIGR01033 YP_750868.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_750869.1 KEGG: son:SO2434 extracellular solute-binding proteins, family 3/GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein, family 3 YP_750870.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO2435 methyltransferase, putative YP_750871.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO2436 methyltransferase, putative YP_750872.1 PFAM: protein of unknown function DUF785; KEGG: ppr:PBPRA1108 hypothetical protein YP_750873.1 KEGG: vvu:VV12151 gonadoliberin III-related protein YP_750874.1 TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: vpa:VP1040 hypothetical protein YP_750875.1 KEGG: son:SO2437 hypothetical protein YP_750876.1 KEGG: vvy:VVA0454 hypothetical protein YP_750877.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2438 transcriptional regulator, LysR family YP_750878.1 KEGG: son:SO2439 SrpA-related protein YP_750879.1 KEGG: son:SO2439.2 hypothetical methyl-accepting chemotaxis protein YP_750880.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_750881.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_750882.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: son:SO2442 thiS protein, putative YP_750883.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: son:SO2443 thiF protein, putative YP_750884.1 KEGG: son:SO2444 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_750885.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_750886.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4077 TonB-dependent receptor, putative YP_750887.1 KEGG: son:SO2557 hypothetical protein YP_750888.1 KEGG: son:SO2559 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_750889.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_750890.1 PFAM: Methyltransferase type 11; KEGG: son:SO2562 hypothetical protein YP_750891.1 PFAM: beta-lactamase domain protein; KEGG: vpa:VP2295 putative hydroxyacylglutathione hydrolase GloB YP_750892.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: son:SO2564 transglycosylase, Slt family YP_750893.1 PFAM: AsmA family protein; KEGG: son:SO2566 AsmA protein YP_750894.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_750895.1 KEGG: son:SO2569 hypothetical protein YP_750896.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: ilo:IL1296 methyl-accepting chemotaxis protein YP_750897.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: reu:Reut_A1003 regulatory protein, LysR:LysR, substrate-binding YP_750898.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal; KEGG: ilo:IL1487 acyl-CoA dehydrogenase YP_750899.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pst:PSPTO1627 short chain dehydrogenase YP_750900.1 PFAM: aminoglycoside phosphotransferase; KEGG: ilo:IL1486 predicted aminoglycoside phosphotransferase YP_750901.1 PFAM: Phosphoglycerate mutase; KEGG: pae:PA1831 hypothetical protein YP_750902.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ilo:IL1485 short chain dehydrogenase family protein YP_750903.1 PFAM: protein of unknown function DUF1379; KEGG: son:SO2591 hypothetical protein YP_750904.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_750905.1 PFAM: NAD-glutamate dehydrogenase; KEGG: son:SO2593 hypothetical protein YP_750906.1 KEGG: son:SO2594 hypothetical protein YP_750907.1 KEGG: son:SO2595 BNR repeat protein YP_750908.1 PFAM: protein of unknown function DUF1329; KEGG: son:SO2596 hypothetical protein YP_750909.1 PFAM: protein of unknown function DUF1302; KEGG: son:SO2597 hypothetical protein YP_750910.1 KEGG: son:SO2598 hypothetical protein YP_750911.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO2600 aminopeptidase N YP_750912.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_750913.1 affects solute and DNA transport through an unknown mechanism YP_750914.1 KEGG: son:SO2603 GAF domain-containing protein YP_750915.1 PFAM: YebG family protein; KEGG: son:SO2604 hypothetical protein YP_750916.1 PFAM: Paraquat-inducible protein A; KEGG: son:SO2604.1 hypothetical protein YP_750917.1 PFAM: Paraquat-inducible protein A; KEGG: ppr:PBPRA1925 hypothetical uncharacterized paraquat-inducible protein A YP_750918.1 PFAM: Mammalian cell entry related domain protein; KEGG: son:SO2606 PqiB family protein YP_750919.1 PFAM: nucleoside recognition domain protein; KEGG: son:SO2607 spore maturation protein A-related protein YP_750920.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_750921.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: son:SO2610 hydrolase, TatD family YP_750922.1 KEGG: son:SO2611 type IV pilus biogenesis protein pilZ YP_750923.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: son:SO2612 DNA polymerase III, delta prime subunit YP_750924.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_750925.1 PFAM: aminodeoxychorismate lyase; KEGG: son:SO2614 conserved hypothetical protein TIGR00247 YP_750926.1 PFAM: aminotransferase, class IV; KEGG: son:SO2615 4-amino-4-deoxychorismate lyase YP_750927.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_750928.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_750929.1 KEGG: son:SO2618 ATP-binding protein, Mrp/Nbp35 family YP_750930.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_750931.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: vvy:VV2526 putative TrkA family protein YP_750932.1 PFAM: protein of unknown function DUF34; KEGG: son:SO2621 conserved hypothetical protein TIGR00486 YP_750933.1 KEGG: ilo:IL1378 hypothetical protein YP_750934.1 PFAM: 17 kDa surface antigen; KEGG: son:SO2622 hypothetical protein YP_750935.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_750936.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_750937.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_750938.1 KEGG: son:SO2626 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_750939.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_750940.1 KEGG: son:SO2628 stress response protein CspD; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_750941.1 KEGG: son:SO2629 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_750942.1 KEGG: pha:PSHAa1688 ribosomal large subunit pseudouridine synthase E (pseudouridylate synthase) (uracil hydrolyase); TIGRFAM: Pseudouridine synthase, Rsu; PFAM: pseudouridine synthase YP_750943.1 PFAM: NUDIX hydrolase; KEGG: son:SO2631 MutT/nudix family protein YP_750944.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_750945.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_750946.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_750947.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: son:SO2636 hypothetical protein YP_750948.1 KEGG: son:SO2637 hypothetical protein YP_750949.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: son:SO2638 leucine dehydrogenase YP_750950.1 PFAM: metallophosphoesterase; KEGG: son:SO1239 hypothetical protein YP_750951.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO1238 acyltransferase family protein YP_750952.1 PFAM: CBS domain containing protein; KEGG: son:SO1237 acetoin utilization protein AcuB, putative YP_750953.1 KEGG: son:SO2639 hypothetical protein YP_750954.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: son:SO4043 TonB domain protein YP_750955.1 PFAM: protein of unknown function DUF1538; KEGG: ppr:PBPRA2812 putative PTS system mannose-specific, factor IIC YP_750956.1 PFAM: protein of unknown function DUF1538; KEGG: ppr:PBPRA2811 hypothetical PTS system mannose-specific, factor IIC YP_750957.1 KEGG: vvy:VV0993 putative nitrogen regulatory protein P-II YP_750958.1 PFAM: CBS domain containing protein; KEGG: ppr:PBPRA2809 hypothetical protein YP_750959.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ppr:PBPRA1401 hypothetical transcriptional regulator, LysR family YP_750960.1 KEGG: ppr:PBPRA1400 hypothetical protein YP_750961.1 PFAM: oxidoreductase domain protein; KEGG: lpn:lpg1321 oxidoreductase YP_750962.1 PFAM: NUDIX hydrolase; KEGG: son:SO0464 MutT/nudix family protein YP_750963.1 KEGG: cps:CPS_3134 hypothetical protein YP_750965.1 PFAM: cation antiporter; KEGG: rru:Rru_A1641 cation antiporter YP_750966.1 PFAM: multiple resistance and pH regulation protein F; KEGG: rru:Rru_A1640 multiple resistance and pH regulation protein F YP_750967.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: rru:Rru_A1639 Na+/H+ antiporter subunit YP_750968.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_750969.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L; KEGG: rru:Rru_A1636 NADH-ubiquinone oxidoreductase, chain 4L YP_750970.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: rba:RB1431 putative multicomponent Na+:H+ antiporter subunit D YP_750971.1 KEGG: rba:RB1431 putative multicomponent Na+:H+ antiporter subunit D YP_750972.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: rru:Rru_A1634 NADH dehydrogenase (quinone) YP_750973.1 KEGG: rru:Rru_A1633 hypothetical protein YP_750974.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_750975.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: noc:Noc_2130 cation transporting ATPase, E1-E2 type YP_750976.1 PFAM: protein of unknown function DUF125, transmembrane; KEGG: dps:DP2435 hypothetical protein YP_750977.1 PFAM: protein of unknown function DUF211; KEGG: dps:DP2436 hypothetical protein YP_750978.1 PFAM: regulatory protein, MarR; KEGG: son:SO2640 transcriptional regulator, MarR family YP_750979.1 KEGG: son:SO2642 hypothetical protein YP_750980.1 PFAM: FAD linked oxidase domain protein; KEGG: son:SO2643 oxidoreductase, FAD-binding, putative YP_750981.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_750982.1 PFAM: protein of unknown function DUF299; KEGG: son:SO2645 hypothetical protein YP_750983.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_750984.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO1387 HD domain protein YP_750985.1 PFAM: protein of unknown function DUF541; KEGG: ilo:IL1781 hypothetical protein YP_750986.1 PFAM: Phosphoglycerate mutase; KEGG: cps:CPS_0333 hypothetical protein YP_750988.1 PFAM: thioesterase superfamily protein; KEGG: son:SO2647 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_750989.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: son:SO2648 DNA-binding response regulator, LuxR family YP_750990.1 PFAM: protein of unknown function DUF938; KEGG: son:SO2050 hypothetical protein YP_750991.1 PFAM: Aldose 1-epimerase; KEGG: son:SO2769 hypothetical protein YP_750992.1 KEGG: son:SO4430 hypothetical protein YP_750993.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_750994.1 PFAM: phospholipase/Carboxylesterase; KEGG: son:SO1999 phospholipase/carboxylesterase family protein YP_750995.1 KEGG: son:SO1998 hypothetical protein YP_750996.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1995 peptidyl-prolyl cis-trans isomerase, FkbP family YP_750997.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: son:SO1994 membrane-bound lytic transglycolase-related protein YP_750998.1 KEGG: son:SO1991 hypothetical protein YP_750999.1 KEGG: son:SO1990 hypothetical protein YP_751000.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO1989 chemotaxis protein CheV YP_751001.1 SMART: peptidase S16, lon domain protein; KEGG: son:SO1987 ATP-dependent protease La (LON) domain protein YP_751002.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO1986 RNA polymerase sigma-70 factor, ECF subfamily YP_751003.1 TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: son:SO1985 transcriptional activator, putative YP_751005.1 KEGG: son:SO1978 hypothetical protein YP_751006.1 PFAM: protein of unknown function DUF307; KEGG: son:SO1977 hypothetical protein YP_751007.1 PFAM: protein of unknown function DUF55; KEGG: son:SO1969 hypothetical protein YP_751008.1 PFAM: protein of unknown function DUF124; KEGG: son:SO1966 conserved hypothetical protein TIGR00266 YP_751009.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family YP_751010.1 PFAM: homogentisate 1,2-dioxygenase; KEGG: son:SO1963 homogentisate 1,2-dioxygenase YP_751011.1 KEGG: son:SO1962 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_751012.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO1954 transporter, LysE family YP_751013.1 PFAM: protein of unknown function DUF482; KEGG: son:SO1953 hypothetical protein YP_751014.1 KEGG: son:SO1952 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_751015.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: hch:HCH_06069 methyl-accepting chemotaxis protein YP_751016.1 KEGG: vvu:VV12353 hypothetical protein YP_751017.1 KEGG: sde:Sde_0340 hypothetical protein YP_751018.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: bfs:BF3021 putative peptidyl-dipeptidase YP_751019.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_751020.1 KEGG: son:SO1939 hypothetical protein YP_751021.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_751022.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_751023.1 PFAM: Auxin Efflux Carrier; KEGG: pha:PSHAa0980 hypothetical protein YP_751024.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: son:SO1933 succinyl-CoA synthetase alpha chain YP_751025.1 catalyzes the interconversion of succinyl-CoA and succinate YP_751026.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: son:SO1931 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) YP_751027.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_751028.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_751029.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_751030.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: son:SO1927.1 hypothetical succinate dehydrogenase, hydrophobic subunit YP_751031.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: son:SO1927 succinate dehydrogenase, cytochrome b556 subunit YP_751032.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_751034.1 KEGG: eli:ELI_07940 putative bacteriophage-acquired protein YP_751035.1 KEGG: vpa:VP1109 hypothetical protein YP_751038.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; KEGG: ppr:PBPRA0678 hypothetical nucleotidyltransferase YP_751039.1 KEGG: ppr:PBPRA0677 hypothetical protein YP_751041.1 PFAM: PAAR repeat-containing protein; KEGG: vpa:VPA1025 hypothetical protein YP_751043.1 PFAM: Rhs element Vgr protein; KEGG: ppr:PBPRA0675 hypothetical protein YP_751044.1 PFAM: protein of unknown function DUF796; KEGG: vpa:VPA1027 hypothetical protein YP_751045.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: ppr:PBPRA0673 putative ATPase with chaperone activity YP_751046.1 PFAM: protein of unknown function DUF1305; KEGG: vpa:VPA1029 hypothetical protein YP_751047.1 PFAM: protein of unknown function DUF879; KEGG: ppr:PBPRA0671 hypothetical protein YP_751048.1 PFAM: protein of unknown function DUF1316; KEGG: vvy:VVA0983 hypothetical protein YP_751049.1 PFAM: virulence protein, SciE type; KEGG: ppr:PBPRA0669 hypothetical protein YP_751050.1 PFAM: protein of unknown function DUF877; KEGG: ppr:PBPRA0668 hypothetical protein YP_751051.1 PFAM: protein of unknown function DUF877; KEGG: ppr:PBPRA0667 hypothetical protein YP_751052.1 PFAM: Uncharacterised conserved protein UCP028301; KEGG: vpa:VPA1035 hypothetical protein YP_751053.1 PFAM: ImpA domain protein; KEGG: ppr:PBPRA0665 hypothetical protein YP_751054.1 PFAM: protein phosphatase 2C domain protein; KEGG: vvy:VVA0989 probable phosphoprotein phosphatase YP_751055.1 KEGG: ppr:PBPRA0663 hypothetical protein YP_751056.1 PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: ppr:PBPRA0662 hypothetical protein YP_751057.1 PFAM: OmpA/MotB domain protein; KEGG: ppr:PBPRA0661 hypothetical protein YP_751058.1 PFAM: protein of unknown function DUF876; KEGG: ppr:PBPRA0660 hypothetical protein YP_751059.1 KEGG: vpa:VPA1042 hypothetical protein YP_751060.1 PFAM: Forkhead-associated protein; KEGG: ppr:PBPRA0658 FHA domain-containing protein YP_751061.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ppr:PBPRA0657 hypothetical serine/threonine protein kinase YP_751062.1 PFAM: OmpA/MotB domain protein; KEGG: pfo:Pfl_1066 OmpA/MotB YP_751063.1 KEGG: son:SO2529 hypothetical protein YP_751064.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO1925 HlyD family secretion protein YP_751065.1 PFAM: acriflavin resistance protein; KEGG: son:SO1924 AcrB/AcrD/AcrF family protein YP_751066.1 PFAM: acriflavin resistance protein; KEGG: son:SO1923 AcrB/AcrD/AcrF family protein YP_751067.1 PFAM: beta-lactamase domain protein; KEGG: ilo:IL0617 Zn-dependent hydrolase, glyoxylase family YP_751068.1 KEGG: hit:NTHI1650 hypothetical protein YP_751069.1 PFAM: protein of unknown function DUF343; KEGG: son:SO2800 hypothetical protein YP_751070.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_751071.1 KEGG: son:SO2802 ABC transporter, ATP-binding protein MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_751072.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: son:SO2803 DNA internalization-related competence protein ComEC/Rec2 YP_751073.1 KEGG: son:SO2804 hypothetical protein YP_751074.1 PFAM: regulatory protein, MarR; KEGG: vfi:VFA0025 transcriptional regulator, MarR family YP_751075.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: pha:PSHAb0539 putative protein involved in iron transport YP_751076.1 KEGG: son:SO1746 hypothetical protein YP_751077.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bpm:BURPS1710b_2160 ribosomal-protein-serine acetyltransferase YP_751078.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: son:SO2259 lipoprotein releasing system transmembrane protein LolC, putative YP_751079.1 KEGG: son:SO2258 lipoprotein releasing system ATP-binding protein LolD; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_751080.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: son:SO2257 lipoprotein releasing system transmembrane protein LolE YP_751081.1 KEGG: son:SO2256 hypothetical protein YP_751082.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; KEGG: son:SO2255 transcription-repair coupling factor YP_751083.1 KEGG: son:SO2254 hypothetical protein YP_751084.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_751085.1 KEGG: son:SO2248 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_751086.1 PFAM: CreA family protein; KEGG: cps:CPS_1436 CreA protein YP_751087.1 KEGG: son:SO2189 conserved hypothetical protein YP_751089.1 PFAM: conserved hypothetical protein 103; KEGG: son:SO2014 conserved hypothetical protein TIGR00103 YP_751090.1 KEGG: son:SO2013 DNA polymerase III, gamma and tau subunits; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_751091.1 KEGG: son:SO2012 adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_751092.1 PFAM: protein of unknown function DUF454; KEGG: son:SO2011 hypothetical protein YP_751093.1 KEGG: son:SO2010 hypothetical protein YP_751094.1 KEGG: son:SO2009 hypothetical protein YP_751095.1 PFAM: protein of unknown function DUF692; KEGG: son:SO2008 hypothetical protein YP_751096.1 KEGG: son:SO2007 hypothetical protein YP_751097.1 PFAM: dihydrouridine synthase, DuS; KEGG: son:SO2006 NifR3/Smm1 family protein YP_751098.1 KEGG: son:SO2005 DksA-type zinc finger protein YP_751099.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO2427 TonB-dependent receptor, putative YP_751100.1 PFAM: nucleoside diphosphate kinase; KEGG: pha:PSHAb0142 nucleoside diphosphate kinase YP_751101.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO2270 ribosomal protein S6 modification protein YP_751102.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: son:SO2269 ferredoxin, 2Fe-2S YP_751103.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_751104.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_751105.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: son:SO2266 HesB/YadR/YfhF family protein YP_751106.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: son:SO2265 NifU family protein YP_751107.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_751108.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: son:SO2263 Rrf2 family protein YP_751109.1 TIGRFAM: serine O-acetyltransferase; KEGG: son:SO2262 serine acetyltransferase YP_751110.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: son:SO2261 RNA methyltransferase, TrmH family, group 1 YP_751111.1 PFAM: inositol monophosphatase; KEGG: son:SO2260 extragenic suppressor protein SuhB YP_751112.1 PFAM: phosphate-starvation-inducible E; KEGG: son:SO2806 hypothetical protein YP_751113.1 PFAM: type IV pilus assembly PilZ; KEGG: son:SO2807 hypothetical protein YP_751114.1 KEGG: son:SO2808 hypothetical protein YP_751115.1 KEGG: son:SO2809 RepA domain protein YP_751116.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: son:SO2822 sensor histidine kinase YP_751117.1 unknown function; when overproduced it confers drug-resistance YP_751118.1 PFAM: carbon starvation protein CstA; KEGG: vpa:VP0540 putative carbon starvation protein A YP_751119.1 KEGG: son:SO2827 hypothetical protein YP_751120.1 KEGG: son:SO2830 hypothetical protein YP_751121.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_751122.1 KEGG: son:SO2832 hypothetical protein YP_751123.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1482 TonB-dependent receptor, putative YP_751124.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: bur:Bcep18194_B2709 NADH-flavin oxidoreductase/NADH oxidase YP_751125.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_751126.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_751127.1 PFAM: Patatin; KEGG: son:SO2836 hypothetical protein YP_751128.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2838 ATP-dependent RNA helicase, DEAD box family YP_751129.1 KEGG: son:SO2839 hypothetical protein YP_751130.1 PFAM: protein of unknown function DUF45; KEGG: son:SO2840 hypothetical protein YP_751131.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ilo:IL1591 glyoxalase/dioxygenase superfamily protein YP_751132.1 KEGG: bur:Bcep18194_B0771 GCN5-related N-acetyltransferase YP_751133.1 PFAM: peptidase M23B; Opacity-associated protein A; KEGG: son:SO2842 peptidase, M23/M37 family YP_751134.1 PFAM: SMC domain protein; KEGG: eca:ECA1108 exonuclease YP_751135.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_751136.1 PFAM: protein of unknown function DUF81; KEGG: son:SO2846 hypothetical protein YP_751137.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ppr:PBPRA1938 putative short-chain dehydrogenase YP_751138.1 KEGG: son:SO1487 hypothetical protein YP_751139.1 PFAM: protein of unknown function DUF1260; KEGG: son:SO1836 hypothetical protein YP_751140.1 PFAM: RNA-binding S4 domain protein; KEGG: son:SO1835 hypothetical protein YP_751141.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: son:SO2861 hypothetical protein YP_751142.1 KEGG: son:SO2862 HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_751143.1 KEGG: son:SO2863 hypothetical protein YP_751144.1 KEGG: son:SO2896 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: helix-hairpin-helix motif; BRCT domain protein; NAD-dependent DNA ligase; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold YP_751145.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA, C-terminal FtsZ-binding region; KEGG: son:SO2897 cell division protein ZipA YP_751146.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: son:SO2898 SMC family protein YP_751147.1 putative role in sulfur assimilation YP_751148.1 KEGG: son:SO2900 hypothetical protein YP_751149.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: hch:HCH_06018 response regulator containing a CheY-like receiver domain and a GGDEF domain YP_751150.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_751151.1 TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: son:SO2903 cysteine synthase A YP_751152.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vvy:VVA0738 transcriptional regulator YP_751153.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: son:SO2911 formate transporter, putative YP_751154.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: xcv:XCV2894 TonB-dependent outer membrane receptor YP_751155.1 KEGG: ppr:PBPRA2749 hypothetical integral membrane protein YP_751156.1 KEGG: son:SO2912 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_751157.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_751158.1 PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein YP_751159.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_751160.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_751161.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_751162.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_751163.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: cps:CPS_1195 intimin/invasin family protein YP_751164.1 PFAM: sodium:dicarboxylate symporter; KEGG: son:SO1948 sodium:dicarboxylate symporter family protein YP_751165.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO0765 threonine efflux protein, putative YP_751166.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cps:CPS_3311 putative phosphonate ABC transporter, permease protein YP_751167.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_3310 putative phosphonate ABC transporter, ATP-binding protein YP_751168.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: cps:CPS_3309 putative phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_751169.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO1946 transcriptional regulatory protein PhoP YP_751170.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO1945 sensor protein PhoQ YP_751171.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO1944 hypothetical protein YP_751172.1 KEGG: son:SO1942 HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_751173.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein, CorA family protein; KEGG: son:SO1941 magnesium and cobalt transport protein CorA YP_751174.1 PFAM: 37kDa nucleoid-associated protein; KEGG: son:SO2177 hypothetical protein YP_751175.1 PFAM: protein of unknown function DUF1414; KEGG: son:SO2176 hypothetical protein YP_751176.1 PFAM: sulfatase; KEGG: son:SO2175 hypothetical protein YP_751177.1 KEGG: aci:ACIAD0819 hypothetical protein; putative signal peptide YP_751178.1 KEGG: cte:CT1157 hypothetical protein YP_751179.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: ssp:SSP0073 putative restriction endonuclease YP_751180.1 PFAM: Ankyrin; KEGG: ani:AN8019.2 hypothetical protein YP_751181.1 KEGG: gsu:GSU3414 hypothetical protein YP_751182.1 PFAM: Glutathione S-transferase, N-terminal domain protein; Glutathione S-transferase, C-terminal domain protein; KEGG: cps:CPS_1156 glutathione-S-transferase domain protein YP_751183.1 KEGG: ppr:PBPRA1945 hypothetical protein YP_751184.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sil:SPO0261 hypothetical protein YP_751185.1 activates fatty acids by binding to coenzyme A YP_751186.1 KEGG: pha:PSHAa1151 two-component member protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; MHYT domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_751187.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: pha:PSHAa1150 response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase) YP_751188.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pha:PSHAa2207 carbohydrates permease YP_751189.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: cps:CPS_3978 oxidoreductase, FAD/FMN-binding YP_751190.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0295 transcriptional regulator, LysR family YP_751191.1 KEGG: son:SO3623 tetraheme cytochrome c YP_751192.1 TIGRFAM: Twin-arginine translocation pathway signal; flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO3058 flavocytochrome c flavin subunit, putative YP_751193.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_3977 transcriptional regulator, LysR family YP_751194.1 PFAM: glutathione synthase; glutathione synthase, ATP-binding; KEGG: vfi:VF0976 glutathione synthetase YP_751195.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_751196.1 SMART: regulatory protein, ArsR; KEGG: vpa:VPA0462 hypothetical protein YP_751197.1 PFAM: permease; KEGG: vfi:VFA0175 hypothetical membrane spanning protein YP_751198.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: son:SO2045 cation efflux family protein YP_751199.1 PFAM: regulatory protein, MarR; KEGG: vpa:VPA1286 putative transcriptional regulator YP_751201.1 KEGG: cps:CPS_4861 hypothetical protein YP_751202.1 KEGG: cps:CPS_4862 hypothetical protein YP_751203.1 PFAM: peptidase M56, BlaR1; KEGG: noc:Noc_0291 hypothetical protein YP_751204.1 PFAM: Penicillinase repressor; KEGG: noc:Noc_0290 penicillinase repressor YP_751205.1 KEGG: pha:PSHAa1267 hypothetical protein YP_751206.1 KEGG: son:SO1947 hypothetical protein YP_751207.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_751208.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_751209.1 PFAM: protein of unknown function DUF195; KEGG: son:SO2041 hypothetical protein YP_751210.1 PFAM: Lytic transglycosylase, catalytic; KEGG: son:SO2040 soluble lytic murein transglycosylase, putative YP_751211.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: son:SO2153 MoxR protein YP_751212.1 PFAM: protein of unknown function DUF58; KEGG: son:SO2151 hypothetical protein YP_751213.1 PFAM: transglutaminase domain protein; KEGG: son:SO2150 transglutaminase family protein YP_751214.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; KEGG: son:SO2149 exodeoxyribonuclease V, gamma subunit YP_751215.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: son:SO2148 exodeoxyribonuclease V, beta subunit YP_751216.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: son:SO2147 exodeoxyribonuclease V, alpha subunit YP_751217.1 KEGG: bur:Bcep18194_C6910 hypothetical protein YP_751221.1 KEGG: pha:PSHAb0268 putative orphan protein YP_751222.1 PFAM: Alkaline phosphatase; KEGG: cps:CPS_3932 alkaline phosphatase family protein YP_751223.1 PFAM: Alkaline phosphatase; KEGG: cps:CPS_3933 alkaline phosphatase family protein YP_751224.1 KEGG: pha:PSHAa2975 hypothetical protein ; secreted protein YP_751225.1 KEGG: vvu:VV12469 excinuclease ATPase subunit YP_751226.1 PFAM: protein of unknown function UPF0153; KEGG: ppr:PBPRA2316 hypothetical protein YP_751227.1 KEGG: ilo:IL2513 hypothetical protein YP_751228.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein; KEGG: ilo:IL2512 uncharacterized iron-regulated membrane protein YP_751229.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_2724 FhuE receptor YP_751230.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_751231.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: cps:CPS_1055 cytochrome c-type protein NapC YP_751232.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: ppr:PBPRA2029 hypothetical periplasmic nitrate reductase small subunit precursor YP_751233.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_751234.1 PFAM: NapD family protein; KEGG: son:SO0849 napD protein YP_751235.1 PFAM: periplasmic nitrate reductase NapE; KEGG: cps:CPS_1060 NapE protein YP_751236.1 KEGG: son:SO2919 hypothetical protein YP_751237.1 PFAM: protein of unknown function UPF0118; KEGG: son:SO2920 hypothetical protein YP_751238.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_751239.1 TIGRFAM: conserved hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal; domain of unknown function DUF1731; KEGG: son:SO2922 hypothetical protein YP_751240.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0997 transcriptional regulator, LysR family YP_751241.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO0996 glyoxalase family protein YP_751242.1 TIGRFAM: Pseudouridine synthase, Rsu; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ppr:PBPRB1023 hypothetical ribosomal small subunit pseudouridine synthase A YP_751243.1 KEGG: par:Psyc_1092 hypothetical protein YP_751244.1 KEGG: vch:VCA0343 hypothetical protein YP_751245.1 PFAM: protein of unknown function DUF214; KEGG: son:SO2926 ABC transporter, permease, putative YP_751246.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO2927 ABC transporter, ATP-binding protein YP_751247.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: son:SO2928 acyl-CoA thioesterase I, putative YP_751248.1 KEGG: son:SO2929 hypothetical protein YP_751249.2 SohB; periplasmic protein; member of the peptidase S49 family YP_751250.1 KEGG: son:SO2934 hypothetical protein YP_751251.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO2935 short chain dehydrogenase YP_751252.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: Helix-hairpin-helix DNA-binding, class 1; KEGG: son:SO1813 DNA-binding protein, putative YP_751253.1 PFAM: conserved hypothetical protein 1620; KEGG: son:SO1811 hypothetical protein YP_751254.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: son:SO1810 hypothetical ATPase YP_751255.1 PFAM: PspC domain protein; KEGG: son:SO1809 phage shock protein C YP_751256.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_751257.1 PFAM: PspA/IM30 family protein; KEGG: son:SO1807 phage shock protein A YP_751258.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO1806 psp operon transcriptional activator YP_751259.1 PFAM: extracellular solute-binding protein, family 5; KEGG: son:SO1805 peptide ABC transporter, periplasmic peptide-binding protein YP_751260.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1804 peptide ABC transporter, permease protein YP_751261.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1803 peptide ABC transporter, permease protein YP_751262.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: son:SO1802 peptide ABC transporter, ATP-binding protein YP_751263.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1801 peptide ABC transporter, ATP-binding protein YP_751264.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_751265.1 TIGRFAM: flavocytochrome c; PFAM: glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0970 fumarate reductase flavoprotein subunit precursor YP_751266.1 PFAM: porin, Gram-negative type; KEGG: son:SO3896 outer membrane porin, putative YP_751267.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2561 transcriptional regulator, LysR family YP_751268.1 PFAM: protein of unknown function DUF819; KEGG: son:SO3828 hypothetical protein YP_751269.1 PFAM: transcription activator, effector binding; SMART: helix-turn-helix- domain containing protein, AraC type; KEGG: bja:blr4000 transcriptional regulatory protein YP_751270.1 PFAM: pentapeptide repeat protein; KEGG: son:SO4064 mcbg protein, putative YP_751271.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO1798 peptidyl-prolyl cis-trans isomerase D YP_751272.1 PFAM: histone family protein DNA-binding protein; KEGG: son:SO1797 DNA-binding protein, HU family YP_751273.1 KEGG: son:SO1796 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_751274.1 binds and unfolds substrates as part of the ClpXP protease YP_751275.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_751276.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_751277.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_751278.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_751279.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO1790 peptidyl-prolyl cis-trans isomerase B YP_751280.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_751281.1 PFAM: tRNA hydroxylase; KEGG: son:SO1788 tRNA-hydroxylase YP_751282.1 KEGG: ilo:IL0684 hypothetical protein YP_751284.1 PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD/DEAH box helicase domain protein; KEGG: pha:PSHAa2091 type I restriction-modification system endonuclease; DEAD/DEAH box helicase motif YP_751285.1 KEGG: bfr:BF2854 hypothetical protein YP_751286.1 PFAM: restriction modification system DNA specificity domain; KEGG: pha:PSHAa2093 type I restriction-modification system, S subunit YP_751287.1 PFAM: N-6 DNA methylase; KEGG: pha:PSHAa2094 type I restriction-modification system, M subunit; N-6 adenine-specific DNA methylase YP_751289.1 PFAM: plasmid recombination enzyme; KEGG: ana:alr9001 similar to mobilization protein YP_751290.1 PFAM: tRNA hydroxylase; KEGG: pha:PSHAa2068 tRNA-hydroxylase YP_751291.1 PFAM: Recombinase; KEGG: pst:PSPTO2317 hypothetical protein YP_751292.1 KEGG: ppr:PBPRA2472 putative tRNA-(MSA)-hydroxylase YP_751293.1 PFAM: protein of unknown function DUF1282; KEGG: son:SO1787 hypothetical protein YP_751294.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_751295.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; KEGG: son:SO1784 ferrous iron transport protein B YP_751296.1 PFAM: FeoA family protein; KEGG: son:SO1783 ferrous iron transport protein A YP_751297.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1834 acetyltransferase, GNAT family YP_751298.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO1832 peptidyl-prolyl cis-trans isomerase C YP_751299.1 PFAM: protein of unknown function DUF885; KEGG: son:SO1831 hypothetical protein YP_751300.1 SMART: Tetratricopeptide domain protein; KEGG: son:SO1829 TPR domain protein YP_751301.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: son:SO1828 TonB2 protein YP_751302.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: son:SO1827 TonB system transport protein ExbD2 YP_751303.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO1826 TonB system transport protein ExbB2 YP_751304.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO1825 MotA/TolQ/ExbB proton channel family protein YP_751305.1 KEGG: son:SO1824 hypothetical protein YP_751306.1 PFAM: Methyltransferase type 11; KEGG: pha:PSHAa1988 S-adenosyl-L-methionine-dependent methyltransferase YP_751307.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: vpa:VP0168 putative iron complex outermembrane recepter protein YP_751308.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_751309.1 helicase involved in DNA repair and perhaps also replication YP_751310.1 PFAM: protein of unknown function DUF81; KEGG: son:SO1818 hypothetical protein YP_751311.1 KEGG: son:SO1817 primosomal replication protein N'', putative YP_751312.1 KEGG: son:SO1816 hypothetical protein YP_751313.1 PFAM: histone deacetylase superfamily; KEGG: son:SO1815 histone deacetylase/AcuC/AphA family protein YP_751314.1 KEGG: son:SO1814 hypothetical protein YP_751315.1 KEGG: son:SO1779 decaheme cytochrome c YP_751316.1 KEGG: son:SO1778 decaheme cytochrome c YP_751317.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1777 decaheme cytochrome c MtrA YP_751318.1 KEGG: son:SO1776 outer membrane protein precursor MtrB YP_751319.1 PFAM: sugar diacid recognition domain protein; KEGG: son:SO1774 hypothetical sugar diacid utilization regulator YP_751320.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: son:SO1771 permease, GntP family YP_751321.1 PFAM: glycerate kinase; KEGG: son:SO1770 glycerate kinase YP_751322.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: son:SO1769 glutamate decarboxylase, putative YP_751323.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: son:SO4548 transposase, IS110 family YP_751324.1 KEGG: vvy:VVA1570 putative integrase YP_751326.1 KEGG: son:SO1862 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_751327.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_751328.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_751329.1 PFAM: protein of unknown function UPF0047; KEGG: eca:ECA3688 hypothetical protein YP_751330.1 SMART: PKD domain containing protein; KEGG: vfi:VFA0516 hypothetical protein YP_751331.1 KEGG: ppr:PBPRA1203 putative PTS system, glucose-specific IIBC; TIGRFAM: PTS system, glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC YP_751332.1 PFAM: PEP-utilizing enzyme; KEGG: pst:PSPTO0954 phosphoenolpyruvate-protein phosphotransferase,EI/HPr/EIIA components YP_751333.1 KEGG: cps:CPS_3258 sensory box/GGDEF/GAF/EAL domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_751334.1 KEGG: son:SO1857 hypothetical ATP-dependent protease YP_751335.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_751336.1 PFAM: ribosome modulation factor; KEGG: son:SO1855 ribosome modulation factor YP_751337.1 KEGG: son:SO1854 hypothetical protein YP_751338.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_751339.1 PFAM: glutaredoxin 2; KEGG: son:SO1852 hypothetical protein YP_751340.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_751341.1 PFAM: Rhodanese domain protein; KEGG: ade:Adeh_0436 rhodanese-like YP_751342.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: son:SO3075 RNA methyltransferase, TrmH family, putative YP_751343.1 KEGG: son:SO3076 hypothetical protein YP_751344.1 PFAM: ATP-NAD/AcoX kinase; KEGG: son:SO3077 hypothetical protein YP_751345.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: son:SO3078 major facilitator family protein, putative YP_751346.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_751347.1 involved in methylation of ribosomal protein L3 YP_751348.1 PFAM: Smr protein/MutS2; KEGG: son:SO3081 Smr domain protein YP_751349.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: son:SO3082 phosphohistidine phosphatase SixA YP_751350.1 PFAM: peptidase M16 domain protein; KEGG: son:SO3083 peptidase, M16 family YP_751351.1 KEGG: son:SO3084 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_751352.1 KEGG: hsa:176 aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) YP_751354.1 KEGG: sdn:Sden_1531 hypothetical protein YP_751355.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_751356.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_751357.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: son:SO3090 MoxR domain protein YP_751358.1 PFAM: protein of unknown function DUF58; KEGG: son:SO3091 hypothetical protein YP_751359.1 KEGG: son:SO3092 hypothetical protein YP_751360.1 PFAM: von Willebrand factor, type A; KEGG: son:SO3093 von Willebrand factor type A domain protein YP_751361.1 PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO3094 TPR domain protein YP_751362.1 KEGG: son:SO3095 hypothetical protein YP_751363.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_751364.1 KEGG: son:SO3097 hypothetical protein YP_751365.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: bha:BH0660 sodium/proline symporter YP_751366.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO3099 long-chain fatty acid transport protein, putative YP_751367.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3102 AcrA/AcrE family protein YP_751368.1 PFAM: acriflavin resistance protein; KEGG: son:SO3103 AcrB/AcrD/AcrF family protein YP_751369.1 KEGG: son:SO3104 hypothetical protein YP_751370.1 PFAM: Rhodanese domain protein; KEGG: son:SO3105 phage shock protein E YP_751371.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: son:SO3106 cold-active serine alkaline protease YP_751372.1 PFAM: CBS domain containing protein; KEGG: cps:CPS_1349 CBS domain protein YP_751373.1 PFAM: YaeQ family protein; KEGG: son:SO3107 hypothetical protein YP_751374.1 TIGRFAM: siroheme synthase; KEGG: son:SO3108 precorrin-2 oxidase / ferrochelatase YP_751375.1 PFAM: Rhodanese domain protein; KEGG: cya:CYA_1705 rhodanese domain protein YP_751376.1 KEGG: son:SO3109 hypothetical protein YP_751377.1 KEGG: sde:Sde_2410 hypothetical protein YP_751378.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_751379.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_751380.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_751381.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_751382.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_751383.1 PFAM: protein of unknown function DUF479; KEGG: son:SO3116 hypothetical protein YP_751384.1 PFAM: Redoxin domain protein; KEGG: son:SO3117 thioredoxin, putative YP_751385.1 PFAM: pseudouridine synthase; KEGG: hch:HCH_04661 pseudouridylate synthases, 23S RNA-specific YP_751386.1 involved in the import of serine and threonine coupled with the import of sodium YP_751387.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO3123 chemotaxis protein CheV YP_751388.1 SMART: protein tyrosine phosphatase, catalytic region; KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative YP_751389.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: ppr:PBPRB0199 putative ATP-dependent RNA helicase YP_751390.1 KEGG: son:SO3126 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_751391.1 PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: son:SO3127 Ada regulatory protein, putative YP_751392.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3128 ABC transporter, ATP-binding/permease protein, putative YP_751393.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_751394.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: son:SO3134 C4-dicarboxylate-binding periplasmic protein YP_751395.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: son:SO3135 C4-dicarboxylate transporter, putative YP_751396.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: son:SO3136 C4-dicarboxylate transport protein YP_751397.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO3136.1 hypothetical two-component sensor histidine kinase protein YP_751398.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO3138 C4-dicarboxylate transport transcriptional regulatory protein YP_751399.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO1917 multidrug resistance protein, putative YP_751400.1 KEGG: son:SO1913 hypothetical protein YP_751401.1 KEGG: son:SO1912 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_751402.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: son:SO1910 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_751403.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_751404.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mag:amb2304 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase YP_751405.1 PFAM: regulatory protein, MerR; KEGG: son:SO1898 transcriptional regulator, putative YP_751406.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal; KEGG: son:SO1897 isovaleryl-CoA dehydrogenase YP_751407.1 PFAM: carboxyl transferase; KEGG: son:SO1896 3-methylcrotonyl-CoA carboxylase beta subunit YP_751408.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: son:SO1895 enoyl-CoA hydratase YP_751409.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO1894 3-methylcrotonyl-CoA carboxylase alpha subunit YP_751410.1 PFAM: pyruvate carboxyltransferase; KEGG: son:SO1893 hydroxymethylglutaryl-CoA lyase YP_751411.1 KEGG: son:SO1892 acetate CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_751412.1 KEGG: son:SO1891 3-oxoacid CoA-transferase subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_751413.1 KEGG: son:SO2355 universal stress protein family YP_751414.1 PFAM: cation antiporter; KEGG: noc:Noc_1287 cation antiporter YP_751415.1 KEGG: noc:Noc_1286 multiple resistance and pH regulation protein F YP_751416.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_751417.1 KEGG: noc:Noc_1284 hypothetical protein YP_751418.1 KEGG: bja:blr7318 hypothetical protein YP_751419.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L; KEGG: noc:Noc_1282 NADH-ubiquinone oxidoreductase, chain 4L YP_751420.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: noc:Noc_1281 NADH dehydrogenase (quinone) YP_751421.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: noc:Noc_1280 NADH dehydrogenase (quinone) YP_751422.1 KEGG: noc:Noc_1279 NADH/ubiquinone/plastoquinone (complex I) YP_751423.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: son:SO2768 acyl-CoA dehydrogenase family protein YP_751424.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_751425.1 PFAM: Na+/H+ antiporter NhaC; KEGG: vfi:VF1630 Na(+)/H(+) antiporter YP_751426.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: son:SO3144 electron transfer flavoprotein, alpha subunit YP_751427.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: son:SO3145 electron transfer flavoprotein, beta subunit YP_751428.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: son:SO3146 DNA-binding protein, H-NS family YP_751429.1 KEGG: son:SO3150 lipoprotein, putative YP_751430.1 PFAM: protein of unknown function UPF0066; KEGG: son:SO3151 hypothetical protein YP_751431.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO3152 acetyltransferase, CysE/LacA/LpxA/NodL family YP_751432.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_751433.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO3162 sensor histidine kinase YP_751434.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: vvu:VV20465 response regulator YP_751435.1 PFAM: Patatin; KEGG: son:SO3155 hypothetical protein YP_751436.1 KEGG: son:SO3163 lipoprotein YP_751437.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: cvi:CV4012 glucose-1-phosphate thymidylyltransferase YP_751438.1 KEGG: son:SO3160 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_751439.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: son:SO3167 dTDP-glucose 4,6-dehydratase YP_751440.1 PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: syf:Synpcc7942_2099 dTDP-4-dehydrorhamnose reductase YP_751441.1 KEGG: son:SO1572 hypothetical protein YP_751442.1 PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO1565 magnesium transporter, putative YP_751443.1 PFAM: glutathione peroxidase; KEGG: son:SO1563 glutathione peroxidase YP_751444.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO1561 peptidase, M1 family YP_751445.1 TIGRFAM: phosphate binding protein; KEGG: son:SO1560 phosphate-binding protein YP_751446.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: son:SO1559 phosphate regulon sensor protein PhoR YP_751447.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO1558 phosphate regulon response regulator PhoB YP_751448.1 PFAM: porin, Gram-negative type; KEGG: son:SO1557 outer membrane porin, putative YP_751449.1 Required for efficient pilin antigenic variation YP_751450.1 PFAM: Glutathione S-transferase, N-terminal domain protein; KEGG: ilo:IL2586 glutathione S-transferase related protein YP_751451.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: pha:PSHAb0471 hypothetical protein YP_751452.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO1552 TPR domain protein YP_751453.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO1551 GGDEF domain protein YP_751454.1 PFAM: conserved hypothetical protein 730; KEGG: son:SO1550 hypothetical protein YP_751455.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_751456.1 KEGG: son:SO1548 hypothetical protein YP_751457.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: son:SO1539 hypothetical protein YP_751458.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_751459.1 KEGG: son:SO1536 hypothetical protein YP_751460.1 PFAM: protein of unknown function DUF423; KEGG: son:SO1535 hypothetical protein YP_751461.1 KEGG: son:SO1534 hypothetical protein YP_751462.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_751464.1 Required for the synthesis of the thiazole moiety YP_751465.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_751466.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_751467.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: vvy:VV0870 exonuclease VII small subunit YP_751468.1 PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase YP_751469.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_751470.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_751471.1 catalyzes the phosphorylation of NAD to NADP YP_751472.1 PFAM: L-lactate permease; KEGG: son:SO1522 L-lactate permease, putative YP_751473.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: son:SO1521 iron-sulfur cluster-binding protein YP_751474.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: son:SO1502 cobalamin synthesis protein/P47K family protein YP_751475.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO1501 ATP-dependent RNA helicase, DEAD box family YP_751476.1 KEGG: son:SO1500 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_751477.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO1490 alcohol dehydrogenase II YP_751478.1 KEGG: son:SO1489 hypothetical protein YP_751479.1 PFAM: thioesterase superfamily protein; KEGG: son:SO1486 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_751480.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase YP_751481.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO3341 antioxidant, AhpC/TSA family YP_751482.1 PFAM: MscS Mechanosensitive ion channel; KEGG: son:SO3340 hypothetical small-conductance mechanosensitive channel YP_751483.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO3339 OmpA family protein YP_751484.1 PFAM: response regulator receiver; KEGG: son:SO3196 response regulator YP_751485.1 PFAM: VacJ family lipoprotein; KEGG: son:SO3197 vacJ lipoprotein, putative YP_751486.1 KEGG: son:SO3198 hypothetical protein YP_751487.1 KEGG: son:SO3199 FlhB domain protein YP_751489.1 KEGG: son:SO2736 hypothetical protein YP_751490.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: cvi:CV3504 probable two-component response regulator YP_751491.1 KEGG: cvi:CV1621 probable sensor/response regulatory hybrid protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_751492.1 KEGG: ava:Ava_4197 hypothetical protein YP_751493.1 PFAM: Redoxin domain protein; KEGG: pha:PSHAa1831 AhpC-TSA YP_751494.1 PFAM: regulatory protein, TetR; KEGG: rba:RB4571 hypothetical protein YP_751495.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: pha:PSHAa0132 hydrolase YP_751496.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: plt:Plut_1539 receptor, putative YP_751497.1 PFAM: regulatory protein, MerR; KEGG: cps:CPS_1955 transcriptional regulator, MerR family YP_751498.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: pha:PSHAa0443 RNAse YP_751499.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_751500.1 TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: msu:MS0967 CpsG protein YP_751501.1 KEGG: ppr:PBPRA2674 putative UTP-glucose-1-phosphateuridylyltransferase, galU; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_751502.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4; KEGG: cps:CPS_2091 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_751503.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4; KEGG: ppr:PBPRA2673 hypothetical undecaprenylphosphateN-acetylglucosamine 1-phosphate transferase YP_751504.1 PFAM: glycosyl transferase, group 1; KEGG: sbo:SBO_0859 putative glycosyl transferase YP_751505.1 KEGG: vvy:VV0303 dTDP-6-deoxy-D-xylo-4-hexulose-3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_751506.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: vvy:VV0302 dTDP-4-dehydrorhamnose reductase YP_751507.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: vfi:VF0167 Glucose-1-phosphate thymidylyltransferase YP_751508.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal; KEGG: vfi:VF0166 dTDP-glucose 4,6-dehydratase YP_751509.1 KEGG: syn:slr2125 hypothetical protein YP_751510.1 PFAM: glycosyl transferase, family 2; KEGG: cac:CAC2174 glycosyltransferase YP_751511.1 KEGG: aci:ACIAD3337 hypothetical protein YP_751512.1 PFAM: polysaccharide biosynthesis protein; KEGG: bba:Bd1688 putative polysaccharide biosynthesis protein CpsL YP_751513.1 TIGRFAM: HAD-superfamily phosphatase, subfamily IIIC; KEGG: nmu:Nmul_A2515 FkbH domain YP_751514.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: gvi:glr3777 probable oxidoreductase YP_751515.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: gvi:glr3776 phosphoglycerate dehydrogenase YP_751516.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: gvi:glr3775 hypothetical protein YP_751517.1 PFAM: glycosyl transferase, family 2; KEGG: gvi:glr3774 hypothetical protein YP_751518.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: ret:RHE_CH00852 probable gluconolactonase protein (calcium-binding regucalcin-like) YP_751519.1 PFAM: lipopolysaccharide biosynthesis; KEGG: son:SO3191 chain length determinant protein YP_751520.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_751521.1 PFAM: polysaccharide export protein; KEGG: son:SO3193 polysaccharide biosynthesis protein YP_751522.1 KEGG: son:SO3194 transcriptional activator rfaH, putative; TIGRFAM: transcriptional activator RfaH; PFAM: transcription antitermination protein NusG; SMART: NGN domain protein YP_751523.1 KEGG: son:SO3343 hypothetical protein YP_751524.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: cps:CPS_0506 putative sucrose phosphorylase YP_751525.1 KEGG: cps:CPS_0507 hypothetical protein YP_751526.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_751527.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_751528.1 PFAM: protein of unknown function DUF179; KEGG: son:SO3346 putative transcriptional regulator YP_751529.1 involved in start site selection during the initiation of translation YP_751530.1 PFAM: ferrochelatase; KEGG: son:SO3348 ferrochelatase YP_751531.1 PFAM: glutathione peroxidase; KEGG: son:SO3349 glutathione peroxidase, putative YP_751532.1 KEGG: cps:CPS_4910 hypothetical protein YP_751533.1 PFAM: type II secretion system protein E; KEGG: son:SO3350 twitching motility protein PilU YP_751534.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SO4268 ISSod2, transposase OrfA YP_751535.1 PFAM: Integrase, catalytic region; KEGG: xcv:XCV3412 ISxac2 transposase YP_751536.1 KEGG: son:SO3350 twitching motility protein PilU YP_751537.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: son:SO3351 twitching motility protein PilT YP_751538.1 TIGRFAM: Protein of unknown function UPF0001; PFAM: alanine racemase domain protein; KEGG: son:SO3352 conserved hypothetical protein TIGR00044 YP_751539.1 KEGG: son:SO3354 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_751540.1 PFAM: protein of unknown function YGGT; KEGG: son:SO3355 hypothetical protein YP_751541.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF167; KEGG: son:SO3356 hypothetical protein YP_751542.1 KEGG: son:SO3357 hypothetical protein YP_751543.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_751544.1 KEGG: son:SO3359 oxygen-independent coproporphyrinogen III oxidase, putative; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_751545.1 PFAM: protein of unknown function DUF885; KEGG: son:SO3361 hypothetical protein YP_751546.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3363 transcriptional regulator, LysR family YP_751547.1 KEGG: son:SO3364 hypothetical protein YP_751548.1 catalyzes the formation of glutamate from glutamine YP_751549.1 PFAM: protein of unknown function DUF469; KEGG: son:SO3366 hypothetical protein YP_751550.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_751551.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: son:SO3368 A/G-specific adenine glycosylase YP_751552.1 PFAM: Fe(II) trafficking protein YggX; KEGG: son:SO3369 hypothetical protein YP_751553.1 PFAM: YceI family protein; KEGG: son:SO3370 hypothetical protein YP_751554.1 PFAM: cytochrome B561; KEGG: son:SO3371 hypothetical cytochrome B561 YP_751555.1 PFAM: SapC family protein; KEGG: pha:PSHAa1142 hypothetical protein YP_751556.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO3517 NADH dehydrogenase YP_751557.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO3519 nitrogen regulatory protein P-II 1 YP_751558.1 TIGRFAM: Prepilin-type cleavage/methylation-like; KEGG: son:SO3520 type IV pilus biogenesis protein, putative YP_751559.1 PFAM: methylation site containing protein; KEGG: son:SO3521 type IV pilus biogenesis protein, putative YP_751560.1 PFAM: methylation site containing protein; KEGG: son:SO3524 type IV pilus biogenesis protein PilE YP_751561.1 KEGG: son:SO3525 type IV pilin biogenesis protein, putative YP_751562.1 KEGG: son:SO3526 type IV pilus assembly protein PilX YP_751563.1 TIGRFAM: Prepilin-type cleavage/methylation-like; KEGG: son:SO3527 type IV pilus assembly protein PilW YP_751564.1 TIGRFAM: type IV pilus modification protein PilV; PFAM: methylation site containing protein; KEGG: son:SO3528 type IV pilus assembly protein PilV YP_751565.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_751566.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3530 peptidyl-prolyl cis-trans isomerase FkbP YP_751567.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_751568.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_751569.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: son:SO3533 riboflavin biosynthesis protein RibF YP_751570.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: son:SO3534 MviN protein YP_751571.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_751572.1 PFAM: regulatory protein, ArsR; KEGG: son:SO3538 transcriptional regulator HlyU YP_751573.1 PFAM: peptidase M20; peptidase M28; KEGG: son:SO3539 peptidase, M28D family YP_751574.1 PFAM: protein of unknown function DUF328; KEGG: son:SO3540 hypothetical protein YP_751575.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: son:SO3541 sodium:alanine symporter family protein YP_751576.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: son:SO3542 putative phosphoketolase YP_751577.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO3545 OmpA family protein YP_751578.1 KEGG: son:SO3546 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_751579.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_751580.1 KEGG: son:SO3548 hypothetical protein YP_751581.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: son:SO3549 hypothetical protein YP_751582.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_751583.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_751584.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_751585.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD YP_751586.1 KEGG: son:SO3418 hypothetical protein YP_751587.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: son:SO3419 trp operon repressor YP_751588.1 PFAM: cytochrome c, class II; KEGG: son:SO3420 cytochrome c' YP_751589.1 PFAM: cytochrome B561; KEGG: son:SO3421 b-type cytochrome, putative YP_751590.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO3422 ribosomal subunit interface protein YP_751591.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase YP_751592.1 KEGG: son:SO1365 hypothetical protein YP_751593.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_751594.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_751595.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_751596.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_751597.1 Essential for efficient processing of 16S rRNA YP_751598.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_751599.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_751600.1 PFAM: cytochrome c assembly protein; KEGG: son:SO1355 hypothetical protein YP_751601.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO1354 hemolysin protein, putative YP_751602.1 PFAM: protein of unknown function DUF962; KEGG: son:SO1353 hypothetical protein YP_751603.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_751604.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_751605.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO; KEGG: son:SO1350 DNA repair protein RecO YP_751606.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_751607.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_751608.1 KEGG: son:SO1347 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_751609.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_751610.1 PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: son:SO1345 sigma-E factor regulatory protein RseC YP_751611.1 PFAM: MucB/RseB family protein; KEGG: son:SO1344 sigma-E factor regulatory protein RseB YP_751612.1 PFAM: Anti sigma-E protein RseA domain protein; KEGG: son:SO1343 sigma-E factor negative regulatory protein YP_751613.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_751614.1 catalyzes the formation of oxaloacetate from L-aspartate YP_751615.1 KEGG: son:SO1340 hypothetical protein YP_751616.1 PFAM: protein of unknown function DUF339; KEGG: son:SO1339 hypothetical protein YP_751617.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_751618.1 KEGG: son:SO1337 hypothetical protein YP_751619.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_751620.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_751621.1 PFAM: protein of unknown function DUF81; KEGG: son:SO1333 hypothetical protein YP_751622.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: son:SO1332 phosphoenolpyruvate-protein phosphotransferase PtsP YP_751623.1 hydrolyzes diadenosine polyphosphate YP_751624.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_751625.1 KEGG: son:SO1329 adenylate cyclase-related protein YP_751626.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1328 transcriptional regulator, LysR family YP_751627.1 PFAM: Hpt domain protein; KEGG: son:SO1327 sensor histidine kinase-related protein YP_751628.1 KEGG: son:SO1326 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_751629.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_751630.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_751631.1 PFAM: type IV pilus assembly PilZ; KEGG: vfi:VF1838 hypothetical protein YP_751632.1 PFAM: iron permease FTR1; KEGG: ilo:IL0111 high-affinity Fe2+/Pb2+ permease YP_751633.1 KEGG: pha:PSHAb0233 hypothetical protein YP_751634.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAb0232 putative TonB dependent receptor YP_751635.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pha:PSHAb0231 mercuric reductase (Hg(II) reductase) YP_751636.1 PFAM: protein of unknown function DUF547; KEGG: pha:PSHAb0230 putative secreted protein similar to a protein present in D.psychrophila YP_751637.1 KEGG: pha:PSHAb0229 putative ABC-type transport system, periplasmic component YP_751638.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pha:PSHAb0228 putative ABC-type transport system, permease component YP_751639.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pha:PSHAb0227 putative ABC transporter ATP-binding YP_751640.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pha:PSHAb0226 putative CDP-alcohol phosphatidyltransferase or phosphatidylglycerophosphate synthase YP_751641.1 KEGG: par:Psyc_1393 possible sterol desaturase YP_751642.1 PFAM: chemotaxis sensory transducer; KEGG: son:SO1144 methyl-accepting chemotaxis protein YP_751643.1 PFAM: EAL domain protein; KEGG: ilo:IL1784 disrupted signaling protein (xGGDEF and EAL domains) YP_751644.1 PFAM: purine and other phosphorylases, family 1; KEGG: son:SO1322 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase YP_751645.1 KEGG: son:SO1321 CobD-related protein YP_751646.1 KEGG: son:SO1320 hypothetical protein YP_751647.1 PFAM: protein of unknown function UPF0126; KEGG: son:SO1319 hypothetical protein YP_751648.1 KEGG: son:SO1318 hypothetical protein YP_751649.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_751650.1 PFAM: peptidase M23B; KEGG: son:SO1314 peptidase, M23/M37 family YP_751651.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_751652.1 KEGG: son:SO1306 hypothetical protein YP_751653.1 KEGG: son:SO1305 hypothetical protein YP_751654.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_751655.1 KEGG: son:SO1303 hypothetical protein YP_751656.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: son:SO1302 chloride channel YP_751657.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_751658.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_751659.1 PFAM: Citrate transporter; KEGG: sde:Sde_2571 endonuclease III/Nth YP_751660.1 KEGG: son:SO1298 general secretion pathway protein B YP_751661.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: son:SO1297 general secretion pathway protein A YP_751662.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; KEGG: vfi:VF2244 tRNA nucleotidyltransferase YP_751663.1 KEGG: son:SO1295 major outer membrane lipoprotein, putative YP_751664.1 KEGG: tcr:508693.190 hypothetical protein Pfam: Plasmodium_HRP TolA PROSITE: GLU_RICH YP_751665.1 KEGG: son:SO1294 ribosomal RNA large subunit methyltransferase A, putative YP_751666.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_751667.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: son:SO1292 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_751668.1 TIGRFAM: dihydroneopterin aldolase; KEGG: son:SO1291 dihydroneopterin aldolase YP_751669.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_751670.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_751671.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_751672.1 PFAM: GatB/Yqey domain protein; KEGG: son:SO1287 hypothetical protein YP_751673.1 KEGG: son:SO1286 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain protein; SMART: Toprim sub domain protein YP_751674.1 TIGRFAM: RNA polymerase sigma factor RpoD; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70, non-essential domain protein; sigma-70 region 1.2; KEGG: son:SO1284 RNA polymerase sigma-70 factor YP_751675.1 KEGG: hch:HCH_00813 hypothetical protein YP_751676.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; Cache domain protein; KEGG: tdn:Tmden_0836 diguanylate cyclase (GGDEF domain) YP_751677.1 PFAM: protein of unknown function DUF599; KEGG: son:SO3776 hypothetical protein YP_751678.1 PFAM: pseudouridine synthase; KEGG: pha:PSHAa1206 23S rRNA pseudouridylate synthase YP_751679.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO1278 methyl-accepting chemotaxis protein YP_751680.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_751681.1 KEGG: son:SO1275 succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_751682.1 PFAM: FAD dependent oxidoreductase; KEGG: son:SO1274 probable oxidoreductase YP_751683.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1273 polyamine ABC transporter, permease protein YP_751684.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1272 polyamine ABC transporter, permease protein YP_751685.1 KEGG: son:SO1271 polyamine ABC transporter, ATP-binding protein; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_751686.1 PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO1270 polyamine ABC transporter, periplasmic polyamine-binding protein YP_751687.1 PFAM: aminotransferase class-III; KEGG: cps:CPS_4663 aminotransferase, class III YP_751688.1 PFAM: glutamine synthetase, catalytic region; KEGG: son:SO1268 glutamine synthetase YP_751689.1 PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: son:SO1267 hypothetical glutamine amidotransferase YP_751690.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: son:SO1265 transcriptional regulator, putative YP_751691.1 PFAM: FAD dependent oxidoreductase; KEGG: son:SO1264 hypothetical oxidoreductase YP_751693.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_751694.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_751695.1 KEGG: vvy:VV2226 hypothetical protein YP_751696.1 PFAM: Rhodanese domain protein; KEGG: son:SO1261 mercaptopyruvate sulfurtransferase YP_751697.1 KEGG: hch:HCH_02647 hypothetical protein YP_751698.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO3496 aldehyde dehydrogenase YP_751699.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_751700.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hch:HCH_01157 methylmalonate-semialdehyde dehydrogenase YP_751701.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: son:SO3501 hypothetical protein YP_751702.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO3502 hypothetical protein YP_751704.1 KEGG: son:SO3374 hypothetical protein YP_751705.1 KEGG: son:SO3376 hypothetical protein YP_751706.1 KEGG: son:SO3377 hypothetical protein YP_751707.1 KEGG: son:SO3378 hypothetical protein YP_751708.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO3379 cyclopropane-fatty-acyl-phospholipid synthase YP_751709.1 PFAM: protein of unknown function DUF1365; KEGG: son:SO3380 hypothetical protein YP_751710.1 PFAM: amine oxidase; KEGG: son:SO3381 hypothetical protein YP_751711.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO3382 oxidoreductase, short-chain dehydrogenase/reductase family YP_751712.1 PFAM: protein of unknown function DUF1486; KEGG: son:SO3383 transcriptional regulator-related protein YP_751713.1 PFAM: cytochrome c552; KEGG: stm:STM4277 nitrite reductase periplasmic cytochrome c552 YP_751714.1 PFAM: NnrS family protein; KEGG: vch:VC2330 putative uncharacterized protein involved in response to NO YP_751715.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: son:SO3384 deoxyribodipyrimidine photolyase YP_751716.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: son:SO3386 hypothetical protein YP_751717.1 PFAM: protein of unknown function DUF368; KEGG: son:SO1400 hypothetical protein YP_751718.1 KEGG: cps:CPS_4932 hypothetical protein YP_751719.1 PFAM: band 7 protein; KEGG: son:SO0445 HflC protein, putative YP_751720.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: son:SO1396 hypothetical protein YP_751721.1 PFAM: protein of unknown function DUF1294; KEGG: son:SO1395 membrane protein,putative YP_751722.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_751723.1 PFAM: peptidase M24; KEGG: cps:CPS_1459 metallopeptidase, M24 family YP_751724.1 PFAM: peptidase M24; KEGG: son:SO1388 aminopeptidase P, putative YP_751725.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: son:SO1236 xanthine/uracil permease family protein YP_751726.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_751727.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_751728.1 TIGRFAM: F0F1-ATPase subunit, putative; KEGG: mba:Mbar_A3104 H(+)-transporting ATP synthase, gene 1 YP_751729.1 KEGG: rfr:Rfer_1164 hypothetical protein YP_751730.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_751731.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_751732.1 KEGG: mac:MA2435 H(+)-transporting ATP synthase, subunit B YP_751733.1 produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit YP_751734.1 PFAM: H+transporting two-sector ATPase, gamma subunit; KEGG: rfr:Rfer_1169 H+-transporting two-sector ATPase, gamma subunit YP_751735.1 PFAM: MltA-interacting MipA family protein; KEGG: vch:VC1318 outer membrane protein OmpV YP_751736.1 KEGG: ccr:CC0125 hypothetical protein YP_751737.1 KEGG: vvu:VV21138 hypothetical protein YP_751738.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sde:Sde_0291 helix-turn-helix, AraC type YP_751739.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cps:CPS_1426 transcriptional regulatory protein RstA YP_751740.1 KEGG: sde:Sde_0289 hypothetical protein YP_751741.1 PFAM: MltA-interacting MipA family protein; KEGG: sde:Sde_0288 hypothetical protein YP_751742.1 PFAM: regulatory protein, MarR; KEGG: ppr:PBPRB1248 hypothetical transcriptional regulator, MarR family YP_751744.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: cps:CPS_4882 hypothetical protein YP_751745.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO1383 ATP-dependent RNA helicase, DEAD box family YP_751746.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO1381 hypothetical protein YP_751747.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_751748.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO3631 glycerate dehydrogenase YP_751749.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_751750.1 PFAM: Nucleotidyl transferase; KEGG: son:SO3634 nucleotidyltransferase family protein YP_751751.1 PFAM: aminoglycoside phosphotransferase; KEGG: son:SO3635 hypothetical phosphotransferase YP_751752.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: son:SO3636 organic solvent tolerance protein YP_751753.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO3637 survival protein surA YP_751754.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_751755.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_751756.1 protein associated with Co2+ and Mg2+ efflux YP_751757.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_751758.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3642 methyl-accepting chemotaxis protein YP_751759.1 KEGG: son:SO3645 hypothetical protein YP_751760.1 PFAM: dihydrofolate reductase region; KEGG: son:SO3646 dihydrofolate reductase YP_751761.1 KEGG: son:SO3647 hypothetical protein YP_751762.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO3648 hypothetical protein YP_751763.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_751764.1 involved in the peptidyltransferase reaction during translation YP_751765.1 PFAM: ribosomal protein L21; KEGG: son:SO3652 ribosomal protein L21 YP_751766.1 PFAM: Polyprenyl synthetase; KEGG: son:SO3653 octaprenyl-diphosphate synthase YP_751767.1 TIGRFAM: uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase superfamily; KEGG: son:SO3654 uracil-DNA glycosylase YP_751768.1 PFAM: methylation site containing protein; KEGG: son:SO3655 pilin, putative YP_751769.1 KEGG: son:SO3656 hypothetical protein YP_751770.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO3657 transporter, LysE family YP_751771.1 KEGG: son:SO3659 thiol:disulfide interchange protein, putative YP_751772.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAb0299 putative TonB-dependent outer membrane receptor YP_751773.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO3664 long-chain-fatty-acid--CoA ligase YP_751774.1 KEGG: son:SO3665 ABC transporter, ATP-binding/permease protein, putative; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_751775.1 PFAM: methylation site containing protein; KEGG: ppr:PBPRA3276 putative MSHA pilin protein MshA YP_751776.1 KEGG: cps:CPS_4848 hypothetical protein YP_751777.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: son:SO1097 putative ribosomal RNA small subunit methyltransferase D YP_751778.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pha:PSHAa1739 regulatory protein, GntR YP_751779.1 KEGG: pha:PSHAa1749 alginate lyase precursor YP_751780.1 PFAM: Heparinase II/III family protein; KEGG: pha:PSHAa1748 chondroitin AC/alginate lyase YP_751781.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: pha:PSHAa1747 pectin degradation protein (sugar phosphate isomerase) YP_751782.1 PFAM: major facilitator superfamily MFS_1; KEGG: sde:Sde_3282 putative hexuronate transporter YP_751783.1 PFAM: PfkB domain protein; KEGG: pha:PSHAa1745 ketodeoxygluconokinase YP_751784.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO0151 hypothetical SAM-dependent methyltransferase YP_751785.1 KEGG: son:SO3807 sterol desaturase family protein YP_751786.1 KEGG: son:SO3808 hypothetical protein YP_751787.1 KEGG: son:SO3811 lipoprotein, putative YP_751788.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO3812 peptidyl-prolyl cis-trans isomerase A YP_751789.1 KEGG: son:SO3813 hypothetical protein YP_751790.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3814 AmpG protein, putative YP_751791.1 specifically modifies tRNA at position G18 YP_751792.1 PFAM: polysaccharide deacetylase; KEGG: cps:CPS_3729 polysaccharide deacetylase family protein YP_751793.1 KEGG: cps:CPS_1552 hypothetical protein YP_751794.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ppr:PBPRA1226 hypothetical protein YP_751795.1 KEGG: ppr:PBPRA1944 hypothetical protein YP_751796.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: sde:Sde_1409 signal transduction histidine kinase-like YP_751797.1 KEGG: mag:amb1049 ABC-type phosphate/phosphonate transport system YP_751798.1 KEGG: ilo:IL1414 catalase; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_751800.1 PFAM: beta-lactamase; KEGG: sil:SPO0810 6-aminohexanoate-dimer hydrolase, putative YP_751801.1 KEGG: son:SO1432 hypothetical protein YP_751802.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO1431 hypothetical protein YP_751803.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1430 anaerobic dimethyl sulfoxide reductase, B subunit YP_751804.1 TIGRFAM: Twin-arginine translocation pathway signal; anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO1429 anaerobic dimethyl sulfoxide reductase, A subunit YP_751805.1 KEGG: son:SO1428 outer membrane protein YP_751806.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1427 decaheme cytochrome c YP_751807.1 KEGG: vvy:VV1376 hypothetical protein YP_751808.1 PFAM: lipase, class 3; KEGG: vvy:VVA0214 predicted lipase YP_751809.1 KEGG: vvy:VV1376 hypothetical protein YP_751811.1 PFAM: CBS domain containing protein; KEGG: son:SO0805 CBS domain protein YP_751812.1 KEGG: cps:CPS_3694 hypothetical protein YP_751813.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_751814.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: hch:HCH_02324 transcriptional regulator YP_751815.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_751816.1 KEGG: son:SO0784 hypothetical protein YP_751818.1 TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; KEGG: mth:MTH830 hypothetical protein YP_751820.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_751821.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_751822.1 PFAM: transposase, IS4 family protein; KEGG: ret:RHE_CH01332 probable insertion sequence transposase protein, IS10 YP_751824.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_751825.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_751826.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_751827.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family YP_751828.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0777 2-octaprenyl-6-methoxyphenol hydroxylase YP_751829.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: son:SO0776 hypothetical protein YP_751830.1 PFAM: protein of unknown function DUF710; KEGG: son:SO0775 hypothetical protein YP_751831.1 KEGG: cpe:CPE1877 probable glycerophosphodiester phosphodiesterase YP_751833.1 KEGG: cfa:484672 similar to fls485 YP_751834.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: son:SO0774 5-formyltetrahydrofolate cyclo-ligase family protein YP_751835.1 KEGG: son:SO1095 O-acetylhomoserine (thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_751836.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: son:SO0772 oxidoreductase, short chain dehydrogenase/reductase family YP_751837.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_751838.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_751839.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: son:SO0771 hypothetical protein YP_751840.1 KEGG: cps:CPS_0516 oxidoreductase, short-chain dehydrogenase/reductase family YP_751841.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cps:CPS_0943 D-beta-hydroxybutyrate dehydrogenase YP_751842.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: cps:CPS_0941 putative lipase YP_751843.1 PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_0940 major facilitator family transporter YP_751844.1 TIGRFAM: PAS sensor protein; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: cps:CPS_0939 sensory box sensor histidine kinase/response regulator YP_751845.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: cps:CPS_0937 DNA-binding response regulator, LuxR family YP_751846.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAa2947 TonB-dependent receptor YP_751847.1 TIGRFAM: esterase, PHB depolymerase family; KEGG: cps:CPS_0935 putative polyhydroxyalkanoate depolymerase YP_751848.1 oxidizes malate to oxaloacetate YP_751849.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0920 acetyltransferase, GNAT family YP_751850.1 PFAM: ribonuclease H; KEGG: ppr:PBPRA1876 hypothetical ribonuclease HI YP_751851.1 KEGG: son:SO0150 lipoprotein, putative YP_751852.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_751853.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0916 putative acetyltransferase YP_751854.1 SMART: Ankyrin YP_751855.1 PFAM: aldo/keto reductase; KEGG: son:SO0900 oxidoreductase, aldo/keto reductase family YP_751856.1 TIGRFAM: cysteine desulfurases, SufS subfamily; PFAM: aminotransferase, class V; KEGG: son:SO3789 aminotransferase, class V YP_751857.1 PFAM: Fe-S metabolism associated SufE; KEGG: son:SO3790 hypothetical protein YP_751858.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: peptidase M19, renal dipeptidase; KEGG: son:SO3791 renal dipeptidase family protein YP_751859.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_751860.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: vpa:VP0295 putative sodium/sulfate symporter YP_751861.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_751862.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_751863.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO3728 uroporphyrin-III C-methyltransferase YP_751864.1 PFAM: phospholipase A1; KEGG: hch:HCH_01113 outer membrane phospholipase A YP_751865.1 KEGG: son:SO3733 hypothetical protein YP_751866.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_751867.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_751868.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: son:SO3738 sulfite reductase (NADPH) flavoprotein alpha-component YP_751869.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_751870.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_751871.1 KEGG: chy:CHY_1906 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_751872.1 KEGG: son:SO4011 hypothetical protein YP_751873.1 PFAM: regulatory protein, TetR; KEGG: son:SO3743 transcriptional regulator, TetR family YP_751874.1 KEGG: son:SO3744 hypothetical protein YP_751875.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_751876.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: son:SO3746 lipid A biosynthesis lauroyl acyltransferase YP_751878.1 PFAM: nitroreductase; KEGG: cps:CPS_3676 nitroreductase family protein YP_751879.1 KEGG: bba:Bd1175 nucleoside-diphosphate-sugar epimerase YP_751880.1 KEGG: son:SO3777 hypothetical protein YP_751881.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_751882.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_751883.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_751884.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_751885.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_751886.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_751887.2 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_751888.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_751889.1 KEGG: son:SO3782 hypothetical protein YP_751890.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO3783 ATP-dependent RNA helicase, DEAD box family YP_751891.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_751892.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: son:SO0895 pirin family protein YP_751893.1 KEGG: son:SO2446 hypothetical protein YP_751894.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: vch:VCA0988 methyl-accepting chemotaxis protein YP_751895.1 KEGG: vpa:VP0089 hypothetical protein YP_751896.1 KEGG: vpa:VP0088 hypothetical protein YP_751897.1 PFAM: PepSY-associated TM helix domain protein; KEGG: son:SO0449 hypothetical protein YP_751898.1 KEGG: son:SO0448 hypothetical protein YP_751899.1 KEGG: son:SO0447 hypothetical protein YP_751900.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: bpa:BPP0079 ferric siderophore receptor YP_751901.1 KEGG: son:SO1940 hypothetical protein YP_751902.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rru:Rru_A3391 putative diguanylate cyclase (GGDEF domain) YP_751903.1 KEGG: ppr:PBPRA1285 hypothetical protein YP_751904.1 KEGG: bca:BCE1051 hypothetical protein YP_751905.1 KEGG: vvy:VVA0209 hypothetical protein YP_751906.1 PFAM: ABC-2 type transporter; KEGG: son:SO3801 ABC transporter, permease protein YP_751907.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3802 ABC transporter, ATP-binding protein YP_751908.1 KEGG: son:SO3803 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_751909.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: son:SO3804 phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative YP_751910.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO3805 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_751911.1 PFAM: branched-chain amino acid transport; KEGG: son:SO1759 hypothetical protein YP_751912.1 PFAM: AzlC family protein; KEGG: son:SO1760 AzlC family protein YP_751913.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1065 FKBP-type peptidyl-prolyl cis-trans isomerase FkpA YP_751914.1 PFAM: WD-40 repeat protein; KEGG: son:SO1064 hypothetical WD domain protein YP_751915.1 PFAM: SlyX family protein; KEGG: son:SO1063 SlyX protein YP_751916.1 KEGG: son:SO1062 polypeptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_751917.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO1061 TPR domain protein YP_751918.1 KEGG: son:SO1060 hypothetical protein YP_751919.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO1059 aminopeptidase N YP_751920.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: son:SO1148 hypothetical protein YP_751921.1 KEGG: cps:CPS_0513 hypothetical protein YP_751922.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: vvu:VV20013 predicted phosphatase YP_751923.1 KEGG: vpa:VPA1560 hypothetical protein YP_751924.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: cps:CPS_1747 hypothetical protein YP_751925.1 KEGG: son:SO4050 hypothetical protein YP_751926.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO4051 HlyD family secretion protein YP_751927.1 PFAM: regulatory protein, MarR; KEGG: son:SO4052 transcriptional regulator, MarR family YP_751928.1 KEGG: rfr:Rfer_1886 putative nitric oxide reductase (subunit B) transmembrane protein YP_751929.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_751930.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: son:SO3748 LysM domain protein YP_751931.1 PFAM: protein of unknown function DUF583; KEGG: son:SO1662 hypothetical Ccm2-related protein YP_751932.1 PFAM: AFG1-family ATPase; KEGG: son:SO3756 hypothetical ATPase YP_751933.1 KEGG: ilo:IL2440 hypothetical protein YP_751934.1 PFAM: protein of unknown function DUF897; KEGG: son:SO3758 hypothetical protein YP_751935.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: son:SO3759 GGDEF domain protein YP_751936.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_751937.1 KEGG: son:SO3761 hypothetical protein YP_751938.1 PFAM: protein of unknown function DUF350; KEGG: son:SO3762 hypothetical protein YP_751939.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_751940.1 KEGG: son:SO3764 hypothetical protein YP_751941.1 PFAM: PspA/IM30 family protein; KEGG: son:SO3765 hypothetical protein YP_751942.1 KEGG: son:SO3766 hypothetical protein YP_751943.1 KEGG: son:SO3767 hypothetical protein YP_751944.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: son:SO3768 ion transporter YP_751945.1 KEGG: son:SO0633 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_751946.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; KEGG: son:SO0632 ATP-dependent helicase HrpB YP_751947.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO0628 GGDEF domain protein YP_751948.1 KEGG: son:SO0627 putative 2'-5' RNA ligase YP_751949.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_751950.1 Regulatory factor involved in maltose metabolism YP_751951.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: son:SO0874 DnaK suppressor protein YP_751952.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: son:SO0873 glutamyl-tRNA synthetase domain protein YP_751953.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region; KEGG: son:SO0872 tRNA nucleotidyltransferase (CCA-adding enzyme) YP_751954.1 KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_751955.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_751956.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_751957.1 KEGG: son:SO0868 hypothetical protein YP_751958.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO0886 hypothetical protein YP_751959.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0885 ABC transporter, ATP-binding protein YP_751960.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO0884 hypothetical protein YP_751961.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: son:SO0882 oxidoreductase, GMC family YP_751962.1 KEGG: son:SO0881 hypothetical protein YP_751963.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO0880 hypothetical protein YP_751964.1 KEGG: son:SO0879 hypothetical protein YP_751965.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: son:SO0878 phosphoribulokinase YP_751966.1 PFAM: Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO0625 hypothetical protein YP_751967.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_751968.1 KEGG: son:SO0623 hypothetical protein YP_751969.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO0622 DNA-binding response regulator YP_751970.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO0621 sensor histidine kinase YP_751971.1 KEGG: son:SO0620 hypothetical protein YP_751972.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_751973.2 PFAM: arginine N-succinyltransferase beta subunit; KEGG: son:SO0618 arginine N-succinyltransferase YP_751974.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_751975.1 KEGG: son:SO0615 hypothetical protein YP_751976.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: son:SO0614 dipeptidyl peptidase IV, putative YP_751977.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: son:SO0613 para-aminobenzoate synthase glutamine amidotransferase, component II YP_751978.1 PFAM: Stringent starvation protein B; KEGG: son:SO0612 stringent starvation protein b YP_751979.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_751980.1 PFAM: cytochrome c1; KEGG: son:SO0610 ubiquinol-cytochrome c reductase cytochrome c1 subunit YP_751981.1 PFAM: Cytochrome b/b6, N-terminal domain protein; Cytochrome b/b6, C-terminal domain protein; KEGG: son:SO0609 ubiquinol-cytochrome c reductase, cytochrome b YP_751982.1 KEGG: son:SO0608 ubiquinol-cytochrome c reductase iron-sulfur subunit; TIGRFAM: Twin-arginine translocation pathway signal; ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_751983.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: son:SO0606 hflC protein YP_751984.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: son:SO0605 hflK protein YP_751985.1 PFAM: GTP-binding protein, HSR1-related; KEGG: son:SO0604 GTP-binding protein HflX YP_751986.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; KEGG: son:SO0603 host factor-I protein YP_751987.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_751988.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_751989.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: son:SO0600 N-acetylmuramoyl-L-alanine amidase YP_751990.1 PFAM: protein of unknown function UPF0079; KEGG: son:SO0599 conserved hypothetical protein TIGR00150 YP_751991.1 KEGG: son:SO0595 hypothetical protein YP_751992.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_751993.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_751994.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_751995.1 PFAM: protein of unknown function DUF6, transmembrane; UAA transporter; KEGG: cps:CPS_3514 membrane protein YP_751996.1 PFAM: MscS Mechanosensitive ion channel; KEGG: son:SO0588 transporter, putative YP_751997.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: son:SO0587 glycerophosphoryl diester phosphodiesterase YP_751998.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO0585 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_751999.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: son:SO0583 bacterioferritin-associated ferredoxin YP_752000.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_752001.1 PFAM: glucose sorbosone dehydrogenase; KEGG: son:SO3898 L-sorbosone dehydrogenase, putative YP_752002.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_752003.1 PFAM: protein of unknown function UPF0227; KEGG: son:SO3900 hypothetical protein YP_752004.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein; KEGG: son:SO3901 lacZ expression regulator YP_752005.1 PFAM: protein of unknown function DUF1249; KEGG: son:SO3902 hypothetical protein YP_752006.1 KEGG: son:SO3903 ADP-ribose pyrophosphatase; TIGRFAM: Nucleoside diphosphate pyrophosphatase; PFAM: NUDIX hydrolase YP_752007.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_752008.1 KEGG: son:SO3905 hypothetical protein YP_752009.1 KEGG: son:SO3906 hypothetical protein YP_752010.1 PFAM: protein of unknown function DUF461; KEGG: son:SO3907 hypothetical protein YP_752011.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: son:SO3908 enoyl-CoA hydratase/isomerase family protein YP_752012.1 KEGG: son:SO3909 hypothetical protein YP_752013.1 KEGG: son:SO3910 hypothetical protein YP_752014.1 KEGG: dde:Dde_2987 transposase YP_752015.1 PFAM: Integrase, catalytic region; KEGG: par:Psyc_0937 putative transposase OrfB YP_752016.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS; KEGG: son:SO3912 TIM-barrel protein, yjbN family YP_752017.1 KEGG: son:SO0147 hypothetical protein YP_752018.1 PFAM: Cupin 2, conserved barrel domain protein YP_752019.1 PFAM: CheC domain protein; KEGG: son:SO3915 putative chemotaxis protein CheX YP_752020.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_752021.1 KEGG: son:SO3917 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_752022.1 KEGG: son:SO3918 hypothetical protein YP_752023.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_752024.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_752025.1 binds single-stranded DNA at the primosome assembly site YP_752026.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_752027.1 PFAM: protein of unknown function DUF481; KEGG: son:SO3931 putative salt-induced outer membrane protein YP_752028.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3933 hypothetical protein YP_752029.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_752030.1 KEGG: son:SO3935 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain protein; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_752031.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO3936 sodium-type flagellar protein MotX YP_752032.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_752033.1 KEGG: son:SO3938 hypothetical protein YP_752034.1 forms a direct contact with the tRNA during translation YP_752035.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_752036.1 PFAM: AFG1-family ATPase; KEGG: son:SO3941 hypothetical protein YP_752037.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3942 serine protease, HtrA/DegQ/DegS family YP_752038.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS YP_752039.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_752040.1 PFAM: BolA family protein; KEGG: son:SO3949 BolA/YrbA family protein YP_752041.1 KEGG: son:SO3950 SpoIIAA family protein YP_752042.1 PFAM: toluene tolerance family protein; KEGG: son:SO3951 hypothetical protein YP_752043.1 PFAM: Mammalian cell entry related domain protein; KEGG: son:SO3952 mce-related protein YP_752044.1 PFAM: protein of unknown function DUF140; KEGG: son:SO3953 putative membrane protein YP_752045.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3954 ABC transporter, ATP-binding protein, putative YP_752046.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: ppr:PBPRA3249 putative Ca2+/Na+ antiporter YP_752047.1 KEGG: son:SO3956 carbohydrate isomerase, KpsF/GutQ family; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_752048.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_752049.1 PFAM: protein of unknown function DUF1239; KEGG: son:SO3958 hypothetical protein YP_752050.1 PFAM: OstA family protein; KEGG: son:SO3959 hypothetical protein YP_752051.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3960 ABC transporter, ATP-binding protein YP_752052.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_752053.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO3962 ribosomal subunit interface protein YP_752054.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: son:SO3963 nitrogen regulatory IIA protein YP_752055.1 PFAM: Uncharacterised P-loop ATPase protein UPF0042; KEGG: son:SO3964 hypothetical protein YP_752056.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: son:SO3965 phosphocarrier protein NPR YP_752057.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO3966 magnesium transporter YP_752058.1 KEGG: son:SO3972 hypothetical transposase YP_752059.1 KEGG: cvi:CV1620 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_752060.1 KEGG: vch:VC1349 sensory box sensor histidine kinase/response regulator YP_752061.1 KEGG: vch:VC1369 hypothetical protein YP_752062.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: vch:VC1370 GGDEF family protein YP_752063.1 KEGG: son:SO0508 hypothetical protein YP_752064.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: son:SO0506 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases YP_752065.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_752066.1 KEGG: sai:Saci_1672 conserved crenarchaeal protein YP_752067.1 PFAM: deoxyUTP pyrophosphatase YP_752068.1 KEGG: cgb:cg3155 deoxycytidine triphosphate deaminase YP_752070.1 KEGG: ilo:IL2088 predicted hydrolase of the alpha/beta superfamily YP_752071.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_752072.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_752073.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VPA0365 putative transcriptional regulator protein YP_752074.1 PFAM: band 7 protein; KEGG: son:SO4128 SPFH domain/Band 7 family protein YP_752075.1 PFAM: band 7 protein; KEGG: son:SO4129 SPFH domain/Band 7 family protein YP_752076.1 PFAM: protein of unknown function DUF107; KEGG: son:SO4130 hypothetical protein YP_752077.1 KEGG: son:SO4131 hypothetical protein YP_752078.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_752079.1 KEGG: son:SO4134 hypothetical protein YP_752080.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: son:SO4136 decarboxylase, pyridoxal-dependent YP_752081.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pha:PSHAa0714 mechanosensitive channel protein YP_752082.1 TIGRFAM: ribokinase; PFAM: regulatory protein, DeoR; PfkB domain protein; Helix-turn-helix, type 11 domain protein; Phosphomethylpyrimidine kinase type-1; KEGG: ecc:c2492 putative carbohydrate kinase YP_752083.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: ppr:PBPRB1417 hypothetical inosine-uridine preferring nucleoside hydrolase YP_752084.1 KEGG: cps:CPS_1160 hypothetical protein YP_752085.1 PFAM: helix-turn-helix domain protein; KEGG: cps:CPS_1159 DNA-binding protein YP_752086.1 SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO0528 hypothetical protein YP_752087.1 PFAM: SEC-C motif domain protein; NERD domain protein; KEGG: ppr:PBPRB1686 hypothetical SecA-related protein YP_752088.1 KEGG: vfi:VFA0705 hypothetical protein YP_752089.1 PFAM: Integrase, catalytic region; KEGG: pha:PSHAa0416 transposase YP_752090.1 PFAM: IstB domain protein ATP-binding protein; KEGG: pha:PSHAa0414 transposase YP_752091.1 KEGG: vfi:VFA0705 hypothetical protein YP_752092.1 KEGG: vfi:VFA0704 hypothetical protein YP_752093.1 PFAM: type III restriction enzyme, res subunit; KEGG: ppr:PBPRA1805 hypothetical protein YP_752094.1 KEGG: ppr:PBPRA1806 hypothetical protein YP_752095.1 PFAM: helix-turn-helix domain protein; KEGG: vvy:VV0142 predicted transcriptional regulator YP_752097.1 KEGG: vfi:VFA1144 hypothetical cytosolic protein YP_752098.1 PFAM: small multidrug resistance protein; KEGG: son:SOA0159 multidrug efflux transporter YP_752099.1 PFAM: putative esterase; KEGG: son:SOA0160 esterase, putative YP_752100.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SOA0161 zinc-binding dehydrogenase YP_752101.1 PFAM: zinc finger, DksA/TraR C4-type; KEGG: pae:PA4870 hypothetical protein YP_752102.1 KEGG: pst:PSPTO5035 glutathione synthetase YP_752103.1 TIGRFAM: glutamate--cysteine ligase; KEGG: pfl:PFL_0273 glutamate--cysteine ligase YP_752104.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vch:VC1890 NADH dehydrogenase YP_752105.1 KEGG: hch:HCH_02210 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_752106.1 PFAM: IstB domain protein ATP-binding protein; KEGG: pha:PSHAa0414 transposase YP_752107.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_752108.1 KEGG: ppr:PBPRB1571 hypothetical protein YP_752109.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_752110.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SOA0164 iron-containing alcohol dehydrogenase YP_752111.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SOA0165 transcriptional regulator, LysR family YP_752112.1 KEGG: psp:PSPPH_1146 TetR family transcriptional regulator-like protein YP_752113.1 PFAM: phage integrase family protein; KEGG: pst:PSPTO3615 site-specific recombinase, phage integrase family YP_752114.1 KEGG: psp:PSPPH_1148 hypothetical protein YP_752115.1 PFAM: phage integrase family protein; KEGG: psp:PSPPH_1149 site-specific recombinase, phage integrase family YP_752116.1 PFAM: phage integrase family protein; KEGG: vvu:VV20655 integrase YP_752117.1 PFAM: AAA-4 family protein; KEGG: tcx:Tcr_0336 hypothetical protein YP_752118.1 TIGRFAM: conserved hypothetical protein; KEGG: nmu:Nmul_A0917 hypothetical protein YP_752119.1 KEGG: son:SOA0173 hypothetical protein YP_752120.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SO4268 ISSod2, transposase OrfA YP_752121.1 PFAM: Integrase, catalytic region; KEGG: xcv:XCV1296 ISxac2 transposase YP_752122.1 KEGG: son:SOA0013 umuD protein YP_752123.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein YP_752125.1 PFAM: outer membrane efflux protein; KEGG: cps:CPS_1957 putative RND efflux system protein YP_752126.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: rpa:RPA2055 possible RND divalent metal cation efflux membrane fusion protein CzcB precursor YP_752127.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: rpa:RPA2056 RND divalent metal cation efflux transporter CzcA YP_752129.1 KEGG: vvy:VV0140 integrase YP_752130.1 PFAM: Group II intron, maturase-specific domain protein; KEGG: plt:Plut_1820 RNA-directed DNA polymerase YP_752131.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: pfl:PFL_5893 Cd(II)/Pb(II)-responsive transcriptional regulator YP_752132.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: pfl:PFL_5892 cadmium-translocating P-type ATPase YP_752133.1 TIGRFAM: lipoprotein signal peptidase; PFAM: phosphoesterase, PA-phosphatase related; peptidase A8, signal peptidase II; KEGG: ilo:IL0633 lipoprotein signal peptidase YP_752134.1 PFAM: Resolvase, N-terminal domain protein; Resolvase helix-turn-helix domain protein; KEGG: sty:HCM1.168 resolvase YP_752135.1 PFAM: transposase Tn3 family protein; KEGG: sec:SC008 transposase YP_752136.1 PFAM: transposase Tn3 family protein; KEGG: reu:Reut_D6457 transposase Tn3 YP_752137.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pha:PSHAb0288 putative cation efflux protein YP_752138.1 KEGG: tdn:Tmden_0321 PAP2 superfamily protein YP_752139.1 PFAM: transposase Tn3 family protein; KEGG: reu:Reut_D6457 transposase Tn3 YP_752140.1 PFAM: transposase Tn3 family protein; KEGG: reu:Reut_D6457 transposase Tn3 YP_752141.1 PFAM: plasmid stabilization system; KEGG: son:SOA0088 plasmid stabilization protein ParE, putative YP_752142.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: son:SOA0087 hypothetical protein YP_752143.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pae:PA0397 probable cation efflux system protein YP_752144.1 PFAM: Resolvase, N-terminal domain protein; Resolvase helix-turn-helix domain protein; KEGG: rru:Rru_B0010 resolvase YP_752145.1 KEGG: bur:Bcep18194_A3305 hypothetical protein YP_752146.1 PFAM: Resolvase, N-terminal domain protein; KEGG: son:SOA0086 site-specific recombinase, resolvase family YP_752147.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: son:SO2048 membrane protein, putative YP_752148.1 KEGG: xac:XAC2430 Tn5044 transposase YP_752149.1 KEGG: psp:PSPPH_1146 TetR family transcriptional regulator-like protein YP_752150.1 PFAM: phage integrase family protein; KEGG: pst:PSPTO3615 site-specific recombinase, phage integrase family YP_752151.1 KEGG: psp:PSPPH_1148 hypothetical protein YP_752152.1 PFAM: phage integrase family protein; KEGG: psp:PSPPH_1149 site-specific recombinase, phage integrase family YP_752154.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: plt:Plut_1820 RNA-directed DNA polymerase YP_752155.1 TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: tbd:Tbd_1341 mercuric reductase MerA YP_752156.1 PFAM: MerC mercury resistance protein; KEGG: neu:NE0840 putative mercury transport protein YP_752157.1 TIGRFAM: mercuric transport protein periplasmic component; PFAM: Heavy metal transport/detoxification protein; KEGG: ilo:IL1645 periplasmic mercuric ion binding protein, MerP YP_752158.1 PFAM: Mercuric transport protein MerT; KEGG: sty:HCM1.234c putative mercuric transport protein YP_752159.1 TIGRFAM: Hg(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: pol:Bpro_2232 transcriptional regulator, MerR family YP_752160.1 KEGG: cps:CPS_0186 hypothetical protein YP_752161.1 PFAM: phage integrase family protein; KEGG: cps:CPS_0185 putative site-specific recombinase, phage integrase family YP_752162.1 PFAM: phage integrase family protein; KEGG: cps:CPS_0184 site-specific recombinase, phage integrase family YP_752163.1 KEGG: son:SO0528 hypothetical protein YP_752165.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_752166.1 KEGG: son:SO0581 hypothetical protein YP_752167.1 PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: son:SO0579 serine/threonine protein kinase, putative YP_752168.1 KEGG: son:SO0578 hypothetical protein YP_752169.1 KEGG: son:SO0577 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_752170.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_0977 TonB-dependent receptor YP_752171.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cps:CPS_0978 transcription regulator, LacI family YP_752172.1 PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_0981 hypothetical protein YP_752173.1 PFAM: glycoside hydrolase, family 37; KEGG: cbu:CBU_1346 trehalase YP_752174.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: son:SO0576 PhoH family protein YP_752175.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_752176.1 KEGG: son:SO0573 hypothetical protein YP_752177.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_752178.1 PFAM: response regulator receiver; KEGG: son:SO0570 response regulator YP_752179.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO0569 sensory box/GGDEF family protein YP_752180.1 PFAM: protein of unknown function DUF1260; KEGG: son:SO0568 hypothetical protein YP_752181.1 KEGG: son:SO0567 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase YP_752182.1 PFAM: ABC-3 protein; KEGG: son:SO0566 ABC 3 transport family protein YP_752183.1 PFAM: periplasmic solute binding protein; KEGG: son:SO0565 adhesion protein, putative YP_752184.1 KEGG: son:SO0564 hypothetical protein YP_752185.1 KEGG: son:SO1155 hypothetical protein YP_752186.1 KEGG: son:SO0563 hypothetical protein YP_752187.1 KEGG: son:SO0562 hypothetical protein YP_752188.1 PFAM: MscS Mechanosensitive ion channel; KEGG: vfi:VFA1107 mechanosensitive ion channel YP_752189.1 PFAM: MaoC domain protein dehydratase; KEGG: son:SO0559 MaoC domain protein YP_752190.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO0558 smtA protein YP_752191.1 PFAM: GumN family protein; KEGG: son:SO0557 hypothetical protein YP_752192.1 KEGG: son:SO0556 hypothetical protein YP_752193.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: son:SO0555 hypothetical protein YP_752194.1 KEGG: son:SO0554 hypothetical protein YP_752195.1 KEGG: son:SO0551 hypothetical protein YP_752196.1 KEGG: son:SO0550 hypothetical protein YP_752197.1 PFAM: response regulator receiver; KEGG: son:SO0549 chemotaxis protein CheY/response regulator receiver domain protein YP_752198.1 PFAM: histone family protein DNA-binding protein; KEGG: son:SO0548 DNA-binding protein, HU family YP_752199.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO0547 hypothetical protein YP_752200.1 KEGG: son:SO0543 hypothetical protein YP_752201.1 KEGG: cjr:CJE1262 general glycosylation pathway protein YP_752202.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF1704; KEGG: son:SO0542 hypothetical protein YP_752203.1 KEGG: ppr:PBPRA2313 hypothetical membrane protein YP_752204.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRA2312 putative ABC-type multidrug transport system, ATPase component YP_752205.1 PFAM: ABC-2 type transporter; KEGG: ppr:PBPRA2311 putative transmembrane protein YP_752207.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: ppr:PBPRB1320 putative sodium/alanine symporter YP_752208.1 KEGG: lic:LIC12691 hypothetical protein YP_752209.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: ilo:IL0788 DSBH domain containing protein YP_752210.1 KEGG: sdn:Sden_0645 hypothetical protein YP_752211.1 KEGG: son:SO4047 cytochrome c family protein YP_752212.1 KEGG: son:SO4048 cytochrome c family protein YP_752213.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_752214.1 PFAM: protein of unknown function DUF1097; KEGG: son:SO3047 hypothetical protein YP_752215.1 KEGG: cps:CPS_3145 hypothetical protein YP_752216.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_752217.1 KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_752218.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_752219.1 PFAM: protein of unknown function DUF81; KEGG: son:SO4058 hypothetical protein YP_752220.1 KEGG: son:SO4142 cytochrome c family protein YP_752221.1 KEGG: son:SO4143 hypothetical protein YP_752222.1 KEGG: son:SO4144 cytochrome c, putative YP_752223.1 PFAM: pseudouridine synthase; KEGG: rfr:Rfer_1895 pseudouridine synthase YP_752224.1 SMART: peptidase S16, lon domain protein; KEGG: son:SO4182 ATP-dependent protease La (LON) domain protein, putative YP_752225.1 KEGG: ilo:IL1449 alpha/beta superfamily hydrolase YP_752226.1 PFAM: conserved hypothetical protein 22; KEGG: son:SO4189 hypothetical protein YP_752227.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_752228.1 PFAM: Integrase, catalytic region; KEGG: par:Psyc_0937 putative transposase OrfB YP_752229.1 KEGG: dde:Dde_2987 transposase YP_752230.1 KEGG: son:SO0454 hypothetical protein YP_752231.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: son:SO0455 hypothetical transporter YP_752232.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: son:SO0456 immunogenic-related protein YP_752233.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: pha:PSHAa2187 hypothetical protein YP_752234.1 KEGG: pha:PSHAb0519 hypothetical protein YP_752235.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_752236.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: eba:ebA5328 conserved hypothetical protein, predicted radical-SAM emzyme YP_752237.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ppr:PBPRB1018 putative deoxycytidylate deaminase YP_752240.1 KEGG: noc:Noc_0526 hypothetical protein YP_752242.1 KEGG: son:SO0090 hypothetical protein YP_752243.1 KEGG: cps:CPS_1152 hypothetical protein YP_752244.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_752245.1 KEGG: pca:Pcar_3022 probable integral membrane protein YP_752246.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_3993 TonB-dependent receptor YP_752247.1 KEGG: cps:CPS_3994 putative lipoprotein YP_752249.1 PFAM: sodium/hydrogen exchanger; KEGG: bfs:BF2202 putative Na+/H+ exchanger YP_752250.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; peptidase M56, BlaR1; KEGG: xac:XAC3362 TonB-like protein YP_752251.1 PFAM: Penicillinase repressor; KEGG: ccr:CC1640 transcriptional regulator, BlaI family YP_752252.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SO0520 heavy metal efflux pump, CzcA family YP_752253.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SO0519 cation efflux protein, putative YP_752255.1 KEGG: son:SO0516 hypothetical protein YP_752256.1 KEGG: son:SO0515 hypothetical protein YP_752257.1 KEGG: son:SO0514 hypothetical protein YP_752258.1 PFAM: Class I peptide chain release factor; KEGG: son:SO0513 hypothetical protein YP_752259.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_752260.1 KEGG: pha:PSHAa1486 hypothetical protein YP_752261.1 KEGG: son:SO2451 hypothetical protein YP_752262.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Alkaline phosphatase; KEGG: son:SO0806 alkaline phosphatase, putative YP_752263.1 PFAM: OsmC family protein; KEGG: vvy:VVA1125 predicted redox protein YP_752264.1 PFAM: luciferase family protein; KEGG: pha:PSHAb0540 putative alkanal monooxygenase (FMN-linked) YP_752265.1 KEGG: son:SO1504 hypothetical protein YP_752266.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cps:CPS_0824 oxidoreductase, short-chain dehydrogenase/reductase family YP_752267.1 PFAM: helix-turn-helix, HxlR type; KEGG: cps:CPS_0823 transcriptional regulator YP_752268.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: son:SO0541 metallo-beta-lactamase family protein YP_752269.1 PFAM: porin, Gram-negative type; KEGG: son:SO1821 outer membrane porin, putative YP_752270.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO2572 peptidyl-prolyl cis-trans isomerase B YP_752271.1 KEGG: pha:PSHAa2344 hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_752272.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rba:RB2931 conserved hypothetical protein-putative acetyltransferase YP_752273.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: vvy:VVA0651 GGDEF family protein YP_752274.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO1364 iron-sulfur cluster-binding protein YP_752275.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_752276.1 KEGG: vpa:VP0375 putative lipoprotein YP_752277.1 KEGG: son:SO0114 hypothetical protein YP_752278.1 KEGG: son:SO2181 hypothetical protein YP_752279.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: son:SO3564 peptidyl-dipeptidase Dcp YP_752281.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_752282.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_752284.1 KEGG: xcb:XC_2154 hypothetical protein YP_752285.1 PFAM: protein of unknown function DUF1499; KEGG: dps:DP1404 hypothetical protein YP_752286.1 KEGG: pha:PSHAb0267 hypothetical protein YP_752287.1 PFAM: DSBA oxidoreductase; KEGG: reu:Reut_A2829 DsbA oxidoreductase YP_752288.1 PFAM: band 7 protein; KEGG: son:SO1377 hypothetical protein YP_752289.1 PFAM: protein of unknown function DUF1449; KEGG: son:SO1376 hypothetical protein YP_752290.1 PFAM: alpha/beta hydrolase fold; KEGG: pfl:PFL_0960 hydrolase, alpha/beta fold family YP_752291.1 PFAM: protein of unknown function DUF81; KEGG: rfr:Rfer_1586 protein of unknown function DUF81 YP_752292.1 KEGG: son:SO0492 hypothetical flavoprotein oxygenase YP_752293.1 KEGG: vfi:VF1129 hypothetical protein YP_752294.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vvy:VVA0239 hypothetical protein YP_752295.1 KEGG: ppr:PBPRB1268 hypothetical protein YP_752296.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: son:SO3588 gpr1/fun34/YaaH family protein YP_752297.1 KEGG: son:SO0941 hypothetical protein YP_752298.1 PFAM: transcriptional regulator domain protein; KEGG: son:SO0940 transcriptional regulator-related protein YP_752299.1 KEGG: son:SO0939 cytochrome c, putative YP_752300.1 KEGG: son:SO0938 hypothetical protein YP_752301.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: son:SO2047 prolyl oligopeptidase family protein YP_752302.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: ppr:PBPRB0852 putative peptidyl-prolyl cis-trans isomerase C YP_752303.1 KEGG: neu:NE1275 hypothetical protein YP_752304.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: cps:CPS_0753 alkaline serine protease, subtilase family YP_752306.1 KEGG: son:SO0721 hypothetical protein YP_752308.1 PFAM: peptidase domain protein; PGAP1 family protein; KEGG: vvy:VVA0946 hypothetical protein YP_752309.1 PFAM: regulatory protein, MarR; KEGG: vpa:VP1763 transcriptional regulator, MarR family YP_752310.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: vpa:VP1764 putative transmembrane protein YP_752311.1 KEGG: cps:CPS_0512 putative lipoprotein YP_752312.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: pae:PA4486 4-carboxymuconolactone decarboxylase YP_752313.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: son:SO0733 cold shock domain family protein YP_752314.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: pae:PA2096 probable transcriptional regulator YP_752315.1 KEGG: bur:Bcep18194_C7122 flavin-containing monooxygenase FMO YP_752316.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: pae:PA2099 short chain dehydrogenase YP_752317.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: rpa:RPA2425 putative lipase/esterase YP_752319.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4069 hypothetical protein YP_752321.1 PFAM: Uncharacterized protein UPF0114; KEGG: son:SO3997 hypothetical protein YP_752322.1 PFAM: helix-turn-helix domain protein; KEGG: son:SO0705 transcriptional regulator, Cro/CI family YP_752323.1 PFAM: NERD domain protein; KEGG: pha:PSHAb0100 putative orphan protein YP_752324.1 PFAM: protein of unknown function DUF88; KEGG: syn:slr1870 hypothetical protein YP_752325.1 KEGG: pgi:PG1436 ATPase, putative YP_752326.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_752327.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_752328.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO0702 MATE efflux family protein YP_752329.1 KEGG: pha:PSHAb0447 hypothetical protein YP_752330.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: son:SO0698 FxsA protein YP_752331.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: son:SO0697 periplasmic divalent cation tolerance protein CutA YP_752332.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_752333.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: son:SO0695 glutathione-regulated potassium-efflux system protein KefC, putative YP_752334.1 KEGG: son:SO0694 galactokinase; TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_752335.1 PFAM: Aldose 1-epimerase; KEGG: son:SO0693 aldose 1-epimerase YP_752336.1 KEGG: vpa:VPA0336 hypothetical protein YP_752337.1 KEGG: son:SO0691 hypothetical protein YP_752338.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing YP_752339.1 KEGG: cps:CPS_4859 putative cation efflux protein YP_752340.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_752341.1 PFAM: histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: pfl:PFL_5112 sensor histidine kinase YP_752342.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_04130 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_752343.1 PFAM: acriflavin resistance protein; KEGG: hch:HCH_04131 cation/multidrug efflux pump YP_752344.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: hch:HCH_04132 membrane-fusion protein YP_752345.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: hch:HCH_04133 outer membrane protein YP_752346.1 PFAM: alpha/beta hydrolase fold; KEGG: ccr:CC1175 haloalkane dehalogenase, putative YP_752347.1 KEGG: son:SO1432 hypothetical protein YP_752348.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO1431 hypothetical protein YP_752349.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1430 anaerobic dimethyl sulfoxide reductase, B subunit YP_752350.1 TIGRFAM: Twin-arginine translocation pathway signal; anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO1429 anaerobic dimethyl sulfoxide reductase, A subunit YP_752351.1 KEGG: son:SO1428 outer membrane protein YP_752352.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1427 decaheme cytochrome c YP_752354.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: ade:Adeh_2101 two component, sigma54 specific, transcriptional regulator, fis family YP_752355.1 PFAM: ATP-binding region, ATPase domain protein domain protein; SMART: extracellular solute-binding protein, family 3; KEGG: gsu:GSU3419 sensor histidine kinase YP_752356.1 KEGG: son:SO0970 fumarate reductase flavoprotein subunit precursor; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_752357.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRA1918 putative glyoxalase family protein YP_752358.1 PFAM: outer membrane porin; KEGG: tdn:Tmden_1456 hypothetical protein YP_752359.1 KEGG: ade:Adeh_2097 hypothetical protein YP_752360.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: dsy:DSY3663 putative fumarate reductase flavoprotein subunit YP_752361.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: gsu:GSU3396 transcriptional regulator, GntR family YP_752362.1 PFAM: Tannase and feruloyl esterase; KEGG: reu:Reut_B4873 feruloyl esterase YP_752363.1 KEGG: noc:Noc_2228 hypothetical protein YP_752364.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_752365.1 PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ppu:PP0808 flavohemoprotein YP_752366.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: noc:Noc_0207 protein phosphatase 2C-like, stage II sporulation E YP_752367.1 PFAM: toluene tolerance family protein; KEGG: gme:Gmet_0784 toluene tolerance YP_752368.1 PFAM: Mammalian cell entry related domain protein; KEGG: pca:Pcar_0449 putative ABC transport system substrate-binding protein YP_752369.1 PFAM: protein of unknown function DUF140; KEGG: pca:Pcar_0447 putative ABC transport system permease protein YP_752370.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mag:amb0331 ABC-type transport system YP_752371.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mag:amb0333 anti-anti-sigma regulatory factor YP_752372.1 KEGG: mag:amb0334 serine phosphatase RsbU YP_752373.1 PFAM: VacJ family lipoprotein; KEGG: ilo:IL1097 surface lipoprotein YP_752374.1 KEGG: hch:HCH_02263 hypothetical protein YP_752375.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: son:SO1652 putative histidinol phosphatase YP_752376.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: son:SO4028 single-strand binding protein YP_752377.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4029 transporter, putative YP_752378.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: son:SO4030 excinuclease ABC, A subunit YP_752379.1 PFAM: peptidase M28; KEGG: son:SO4032 hypothetical protein YP_752380.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO4034 ATP-dependent RNA helicase DeaD YP_752381.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4040 integral membrane domain protein YP_752382.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_752383.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_2724 FhuE receptor YP_752384.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; Endonuclease/exonuclease/phosphatase; KEGG: son:SO1066 extracellular nuclease YP_752385.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vvy:VVA0728 methyl-accepting chemotaxis protein YP_752386.1 KEGG: son:SO4018 hypothetical protein YP_752387.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: son:SO4078 PmbA protein YP_752388.1 PFAM: protein of unknown function DUF615; KEGG: son:SO4079 hypothetical protein YP_752389.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: son:SO4080 hypothetical protein YP_752391.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_4160 substrate-binding transcriptional regulator, LysR family YP_752392.1 KEGG: cps:CPS_4161 hypothetical protein YP_752393.1 KEGG: son:SO4087 conserved hypothetical protein YP_752394.1 KEGG: son:SO4088 conserved hypothetical protein YP_752395.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO4089 HlyD family secretion protein YP_752396.1 PFAM: outer membrane efflux protein; KEGG: son:SO4090 outer membrane efflux protein YP_752397.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: son:SO4091 TldD protein YP_752398.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: son:SO4092 hydrolase, carbon-nitrogen family YP_752399.1 TIGRFAM: conserved hypothetical protein; KEGG: son:SO4093 hypothetical protein YP_752400.1 involved in the processing of the 5'end of 16S rRNA YP_752401.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO4095 maf protein YP_752402.1 PFAM: Rod shape-determining protein MreD; KEGG: son:SO4096 rod shape-determining protein MreD YP_752403.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_752404.1 functions in MreBCD complex in some organisms YP_752405.1 KEGG: son:SO4100 MSHA biogenesis protein MshQ YP_752406.1 KEGG: son:SO4101 MSHA biogenesis protein MshP YP_752407.1 PFAM: methylation site containing protein; KEGG: son:SO4102 MSHA biogenesis protein MshO YP_752408.1 PFAM: methylation site containing protein; KEGG: son:SO4103 MSHA pilin protein MshD YP_752409.1 PFAM: methylation site containing protein; KEGG: son:SO4104 MSHA pilin protein MshC YP_752410.1 PFAM: methylation site containing protein; KEGG: son:SO4105 MSHA pilin protein MshA YP_752411.1 PFAM: methylation site containing protein; KEGG: son:SO4106 MSHA pilin protein MshB YP_752412.1 KEGG: son:SO4107 hypothetical protein YP_752413.1 PFAM: type II secretion system protein; KEGG: son:SO4108 MSHA biogenesis protein MshG YP_752414.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: son:SO4109 MSHA biogenesis protein MshE YP_752415.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO4110 MSHA biogenesis protein MshN, putative YP_752416.1 KEGG: son:SO4111 MSHA biogenesis protein MshM YP_752417.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain protein; KEGG: son:SO4112 MSHA biogenesis protein MshL YP_752418.1 KEGG: son:SO4113 MSHA biogenesis protein MshK YP_752419.1 KEGG: son:SO4114 MSHA biogenesis protein MshJ YP_752420.1 KEGG: vch:VC0399 MSHA biogenesis protein MshI YP_752421.1 KEGG: son:SO4114.2 hypothetical biogenesis protein MshI YP_752422.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_752423.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: son:SO4118 malate oxidoreductase, putative YP_752424.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_752425.1 KEGG: son:SO4121 hypothetical protein YP_752426.1 KEGG: son:SO4121 hypothetical protein YP_752427.1 TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; KEGG: son:SO4122 primosomal protein N' YP_752428.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_752429.1 PFAM: Sporulation domain protein; KEGG: son:SO4124 cell division protein FtsN, putative YP_752430.1 heat shock protein involved in degradation of misfolded proteins YP_752431.1 heat shock protein involved in degradation of misfolded proteins YP_752432.1 PFAM: protein of unknown function DUF971; KEGG: son:SO4164 hypothetical protein YP_752436.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: son:SO4548 transposase, IS110 family YP_752437.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_752438.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_752439.1 PFAM: Patatin; KEGG: son:SO0428 hypothetical protein YP_752440.1 KEGG: son:SO0427 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_752441.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_752442.1 KEGG: son:SO0425 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_752443.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_752444.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_752445.1 involved in regulation of beta-lactamase; putative signaling protein YP_752446.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: son:SO0421 AmpD protein YP_752447.1 KEGG: ppr:PBPRA3199 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_752448.1 PFAM: Fimbrial protein pilin; methylation site containing protein; KEGG: xcb:XC_1058 pilin YP_752449.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: son:SO0416 type IV pilus biogenesis protein PilB YP_752450.1 PFAM: type II secretion system protein; KEGG: son:SO0415 type IV pilus biogenesis protein PilC YP_752451.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; KEGG: son:SO0414 leader peptidase (prepilin peptidase) / N-methyltransferase YP_752452.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_752453.1 PFAM: protein of unknown function DUF1342; KEGG: son:SO0412 hypothetical protein YP_752454.1 PFAM: protein of unknown function DUF329; KEGG: son:SO0411 hypothetical protein YP_752455.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: son:SO0410 mutator mutT protein YP_752456.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_752457.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_752458.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_752459.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_752460.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_752461.1 PFAM: peptidase M23B; KEGG: son:SO4212 peptidase, M23/M37 family YP_752462.1 KEGG: son:SO4213 hypothetical protein YP_752463.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_752464.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_752465.1 PFAM: cell division protein FtsA; KEGG: son:SO4216 cell division protein FtsA YP_752466.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type; KEGG: son:SO4217 cell division protein FtsQ YP_752467.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_752468.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_752469.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: son:SO4220 cell division protein FtsW YP_752470.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_752471.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_752472.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO4223 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_752473.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_752474.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: son:SO4225 peptidoglycan synthetase FtsI YP_752475.1 PFAM: cell division protein FtsL; KEGG: son:SO4226 cell division protein FtsL YP_752476.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: son:SO4227 putative S-adenosyl methionine adenyltransferase YP_752477.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_752478.1 KEGG: son:SO4229 hypothetical protein YP_752479.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: son:SO4230 glycerol kinase YP_752480.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO4232 long-chain fatty acid transport protein YP_752481.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_752482.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_752483.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_752484.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_752485.1 KEGG: son:SO4240 hypothetical protein YP_752486.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO4241 ATP-dependent DNA helicase RecQ YP_752487.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: son:SO4242 hypothetical protein YP_752488.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein YP_752489.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_752490.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_752491.1 required for 70S ribosome assembly YP_752492.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_752493.1 KEGG: son:SO4249 DNA/pantothenate metabolism flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_752494.1 catalyzes the formation of dUMP from dUTP YP_752495.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_752496.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: son:SO4252 prolyl oligopeptidase family protein YP_752497.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: son:SO4252 prolyl oligopeptidase family protein YP_752498.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_752499.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_752500.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_752501.1 TIGRFAM: conserved hypothetical protein; PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: son:SO4257 conserved hypothetical protein TIGR00255 YP_752502.1 KEGG: nfa:nfa34960 hypothetical protein YP_752503.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase C-terminal domain protein; KEGG: nfa:nfa34950 hypothetical protein YP_752504.1 PFAM: protein of unknown function DUF1006; KEGG: son:SO4332 hypothetical protein YP_752505.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_752506.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; KEGG: son:SO0368 helicase YP_752507.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: son:SO0367 hypothetical protein YP_752508.1 KEGG: son:SO0366 hypothetical protein YP_752509.1 TIGRFAM: Twin-arginine translocation pathway signal; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0365 hypothetical permeases of the major facilitator superfamily YP_752511.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_752512.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_752513.1 PFAM: alpha/beta hydrolase fold; KEGG: vvy:VV1990 lactonizing lipase YP_752514.1 KEGG: aci:ACIAD3308 lipase chaperone YP_752515.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: vpa:VPA1656 ferric vibrioferrin receptor YP_752516.1 PFAM: chemotaxis sensory transducer; KEGG: ppr:PBPRB1866 hypothetical methyl-accepting chemotaxis protein YP_752517.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: pha:PSHAa2408 transcriptional regulator (AraC/XylS) YP_752518.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa2409 permease YP_752519.1 PFAM: HPP family protein; KEGG: tdn:Tmden_1127 HPP YP_752520.1 KEGG: pha:PSHAb0203 putative SmvA (YddG) efflux protein YP_752521.1 PFAM: protein of unknown function DUF548; KEGG: son:SO4658 hypothetical protein YP_752522.1 PFAM: protein of unknown function DUF519; KEGG: son:SO4659 hypothetical protein YP_752523.1 PFAM: peptidase M20; peptidase M28; KEGG: ilo:IL1071 probable aminopeptidase fused to fibronectin type 3 domain YP_752524.1 PFAM: Lytic transglycosylase, catalytic; KEGG: son:SO4660 transglycosylase SLT domain protein YP_752525.1 KEGG: son:SO4662 lemA protein YP_752526.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: son:SO4692 AcrB/AcrD/AcrF family protein YP_752527.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO4693 multidrug resistance protein, AcrA/AcrE family YP_752528.1 KEGG: vfi:VFA0087 outer membrane protein RomA YP_752529.1 PFAM: regulatory protein, TetR; KEGG: vvy:VVA1153 transcriptional regulator YP_752530.1 KEGG: son:SO4696 hypothetical 3-methyladenine DNA glycosylase YP_752531.1 KEGG: son:SO4698 hypothetical protein YP_752532.1 DHBP synthase; functions during riboflavin biosynthesis YP_752533.1 KEGG: sru:SRU_1646 hypothetical protein YP_752534.1 SMART: helix-turn-helix domain protein; KEGG: tcx:Tcr_2183 transcriptional regulator, XRE family YP_752535.1 KEGG: lpp:lpp0491 hypothetical protein YP_752536.1 PFAM: regulatory protein, MerR; KEGG: vpa:VPA1142 putative transcriptional regulator, MerR family YP_752537.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: vpa:VPA1141 gamma-carboxymuconolactone decarboxylase YP_752538.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: son:SO4699 oligopeptidase A YP_752539.1 KEGG: son:SO4700 hypothetical protein YP_752540.1 KEGG: son:SO4701 hypothetical protein YP_752541.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_752542.1 PFAM: Integrase, catalytic region; KEGG: bja:bll1855 putative transposase YP_752543.1 PFAM: sodium/sulphate symporter; KEGG: bpe:BP0380 putative sodium:sulfate symportert YP_752545.1 PFAM: adenylate cyclase; KEGG: bfs:BF0324 hypothetical protein YP_752546.1 PFAM: phosphate-selective porin O and P; KEGG: noc:Noc_2418 phosphate-selective porin O and P YP_752548.1 PFAM: protein of unknown function DUF47; KEGG: tma:TM0914 hypothetical protein YP_752549.1 PFAM: phosphate transporter; KEGG: tma:TM0917 phosphate permease, putative YP_752550.1 KEGG: cps:CPS_1942 hypothetical protein YP_752551.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: cps:CPS_1943 cation efflux system protein CzcA YP_752552.1 KEGG: cps:CPS_1944 hypothetical protein YP_752553.1 KEGG: ilo:IL0061 outer membrane protein YP_752554.1 PFAM: regulatory protein, LuxR; KEGG: cps:CPS_1945 hypothetical protein YP_752556.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ret:RHE_CH02498 probable transcriptional regulator protein, LysR family YP_752557.1 TIGRFAM: anaerobic c4-dicarboxylate antiporter, Dcu family; PFAM: anaerobic c4-dicarboxylate membrane transporter; KEGG: vfi:VF2354 anaerobic C4-dicarboxylate transporter YP_752558.1 KEGG: son:SO1412 hypothetical protein YP_752560.1 KEGG: son:SO3623 tetraheme cytochrome c YP_752561.1 TIGRFAM: Twin-arginine translocation pathway signal; flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO3624 flavocytochrome c flavin subunit YP_752562.1 KEGG: cps:CPS_3986 hypothetical protein YP_752563.1 PFAM: protein of unknown function DUF347; KEGG: mlo:mlr4456 putative integral membrane protein YP_752564.1 PFAM: protein of unknown function DUF347; KEGG: dar:Daro_2299 protein of unknown function DUF347 YP_752565.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: dar:Daro_2298 response regulator receiver:transcriptional regulatory protein, C-terminal YP_752566.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: bur:Bcep18194_A5020 periplasmic sensor signal transduction histidine kinase YP_752567.1 PFAM: helix-turn-helix domain protein; KEGG: son:SO4705 transcriptional regulator, putative YP_752568.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_752569.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO3660.1 hypothetical ferredoxin YP_752570.1 KEGG: son:SO3660 sigma-54 dependent transcriptional regulator/sensory box protein; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; AAA ATPase YP_752571.1 PFAM: Paraquat-inducible protein A; KEGG: son:SO4710 hypothetical protein YP_752572.1 KEGG: psp:PSPPH_3940 hypothetical protein YP_752573.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: ilo:IL0935 signaling protein with a sensor domain, HAMP, GGDEF and EAL domains YP_752574.1 KEGG: ilo:IL0934 hypothetical protein YP_752575.1 PFAM: globin; KEGG: pha:PSHAa0458 protozoan/cyanobacterial globin protein YP_752576.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO4711 HD domain protein YP_752577.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: son:SO4713 menaquinone-specific isochorismate synthase, putative YP_752578.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: son:SO4715 hypothetical protein YP_752579.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4717 sensor histidine kinase YP_752580.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO4718 sigma-54 dependent response regulator YP_752581.1 KEGG: son:SO4719 putative sulfate transport system substrate-binding protein YP_752582.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4720 ABC transporter, permease protein YP_752583.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO4721 ABC transporter, ATP-binding protein YP_752584.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: son:SO4722 molybdopterin-guanine dinucleotide biosynthesis protein YP_752585.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: son:SO4723 molybdopterin biosynthesis MoeA protein, putative YP_752586.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_752587.1 KEGG: son:SO4725 hypothetical protein YP_752588.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_752589.1 KEGG: son:SO4685 hypothetical protein YP_752590.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_752591.1 PFAM: glycosyl transferase, family 25; KEGG: msu:MS0446 glycosyltransferase involved in LPS biosynthesis YP_752592.1 KEGG: hit:NTHI0649 ADP-heptose--lipooligosaccharide heptosyltransferase III YP_752593.1 TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: pca:Pcar_0024 ADP-L-glycero-D-mannoheptose-6-epimerase YP_752594.1 TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: cps:CPS_4205 glycerol-3-phosphate cytidyltransferase YP_752595.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: gox:GOX2059 hypothetical protein YP_752596.1 KEGG: reu:Reut_A2557 glycosyl transferase, family 9 YP_752597.1 PFAM: glycosyl transferase, family 8 YP_752598.1 PFAM: glycosyl transferase, family 9; KEGG: son:SO4678 heptosyl transferase, glycosyltransferase family 9 protein YP_752599.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_752600.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: son:SO4676 3-deoxy-D-manno-octulosonic-acid (KDO) transferase YP_752601.1 PFAM: regulatory protein, TetR; KEGG: son:SO4675 transcriptional regulator, TetR family YP_752602.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_752603.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_752604.1 PFAM: Rhodanese domain protein; KEGG: son:SO4672 glpE protein YP_752605.1 PFAM: Rhomboid family protein; KEGG: son:SO4671 glpG protein YP_752606.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO4670 enhancing lycopene biosynthesis protein YP_752607.1 KEGG: son:SO4669 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_752608.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_752609.1 PFAM: cytochrome c, class I; KEGG: son:SO4666 cytochrome c YP_752610.1 KEGG: son:SO4727 hypothetical protein YP_752611.1 KEGG: son:SO4728 hypothetical protein YP_752612.1 KEGG: son:SO4729 hypothetical protein YP_752613.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0123 acyltransferase family protein YP_752614.1 PFAM: alpha/beta hydrolase fold; KEGG: bha:BH2279 hypothetical protein YP_752615.1 PFAM: MscS Mechanosensitive ion channel; KEGG: son:SO0121 hypothetical small-conductance mechanosensitive channel YP_752616.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_752617.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_752618.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: son:SO0096 histidine utilization repressor YP_752619.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_752620.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pha:PSHAa1832 cryptic haloacid dehalogenase 1 (partial) YP_752621.1 PFAM: Amidohydrolase 3; KEGG: cps:CPS_2795 amidohydrolase family protein YP_752622.1 KEGG: son:SO0637 hypothetical protein YP_752623.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvu:VV12537 putative acetyltransferase YP_752624.1 PFAM: Integrase, catalytic region; KEGG: xcv:XCV3412 ISxac2 transposase YP_752625.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SO4268 ISSod2, transposase OrfA YP_752627.1 KEGG: son:SO3280 hypothetical protein YP_752628.1 PFAM: protein of unknown function DUF885; KEGG: cps:CPS_3202 putative lipoprotein YP_752629.1 KEGG: ilo:IL2526 predicted hydrolase of the alpha/beta superfamily YP_752630.1 TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0084 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_752631.1 KEGG: son:SO2207 hypothetical protein YP_752632.1 PFAM: thioesterase superfamily protein; KEGG: son:SO0080 hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_752633.1 KEGG: son:SO0079 hypothetical protein YP_752634.1 PFAM: thioesterase superfamily protein; KEGG: son:SO0077 hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_752636.1 KEGG: pfl:PFL_0585 hypothetical protein YP_752637.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0075 AMP-binding family protein YP_752638.1 KEGG: son:SO0074 hypothetical protein YP_752639.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0073 ABC transporter, ATP-binding protein YP_752640.1 PFAM: regulatory protein GntR, HTH; KEGG: son:SO0072 transcriptional regulator, GntR family YP_752641.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: son:SO0071 hydrolase, alpha/beta hydrolase fold family YP_752642.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA YP_752643.1 PFAM: ABC-2 type transporter; KEGG: son:SO0069 transport protein, putative YP_752644.1 KEGG: son:SO0068 hypothetical protein YP_752645.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; CHASE4 domain protein; KEGG: vch:VC2285 GGDEF family protein YP_752646.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_752647.1 PFAM: methylation site containing protein; KEGG: son:SO4105 MSHA pilin protein MshA YP_752648.1 PFAM: regulatory protein, TetR; KEGG: son:SO3494 transcriptional regulator, TetR family YP_752649.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3493 RND multidrug efflux membrane fusion protein MexE YP_752650.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: son:SO3492 RND multidrug efflux transporter MexF YP_752651.1 PFAM: PfkB domain protein; KEGG: cps:CPS_2648 carbohydrate kinase, PfkB family YP_752652.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ccr:CC1136 TonB-dependent receptor YP_752653.1 PFAM: major facilitator superfamily MFS_1; KEGG: ccr:CC1133 transporter, putative YP_752654.1 KEGG: atc:AGR_pTi_251 sucrose phosphorylase SplA; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_752655.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hch:HCH_04796 transcriptional regulator YP_752656.1 PFAM: NLP/P60 protein; KEGG: son:SO0061 lipoprotein, NLP/P60 family YP_752657.1 PFAM: regulatory protein, TetR; KEGG: nmu:Nmul_A1967 transcriptional regulator, TetR family YP_752659.1 PFAM: transport-associated; KEGG: pha:PSHAa0325 hypothetical protein YP_752661.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: vpa:VP0080 putative sigma-54 interacting response regulator transcription regulator protein YP_752662.1 PFAM: Dual specificity protein phosphatase; diacylglycerol kinase, catalytic region; KEGG: pha:PSHAb0333 methylglyoxal synthase YP_752663.1 KEGG: pha:PSHAa0536 hypothetical protein YP_752664.1 PFAM: protein of unknown function DUF1328; KEGG: pha:PSHAa0537 hypothetical protein YP_752665.1 PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_3354 hypothetical protein YP_752666.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_752667.1 PFAM: Bile acid:sodium symporter; KEGG: cps:CPS_3442 putative arsenical-resistance protein YP_752668.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; regulatory protein, ArsR; KEGG: cps:CPS_3358 transcriptional regulator, ArsR family YP_752669.1 KEGG: gsu:GSU1927 sensory box/response regulator; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; SMART: PAS domain containing protein YP_752670.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: tbd:Tbd_1268 multi-sensor hybrid histidine kinase YP_752671.1 KEGG: hch:HCH_02557 hypothetical protein YP_752672.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: gme:Gmet_1669 TonB-dependent receptor, plug YP_752673.1 KEGG: hch:HCH_02557 hypothetical protein YP_752674.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: gme:Gmet_1669 TonB-dependent receptor, plug YP_752675.1 PFAM: SpoVT/AbrB domain protein; KEGG: xac:XACa0028 plasmid stable inheritance protein I YP_752676.1 KEGG: hch:HCH_03615 hypothetical protein YP_752677.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_752678.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_752681.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0054 conserved hypothetical protein TIGR00275 YP_752682.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_752683.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_752684.1 PFAM: Rhodanese domain protein; KEGG: son:SO0050 rhodanese domain protein YP_752685.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_752686.1 PFAM: peptidase M23B; KEGG: son:SO0048 peptidase, M23/M37 family YP_752687.1 PFAM: protein of unknown function DUF610, YibQ; KEGG: son:SO0046 hypothetical protein YP_752688.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: son:SO0045 Rrf2 family protein YP_752689.1 PFAM: protein of unknown function UPF0153; KEGG: son:SO0044 hypothetical protein YP_752690.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_752691.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_752692.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4737 iron-sulfur cluster-binding protein YP_752693.1 KEGG: son:SO4738 hypothetical protein YP_752694.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_752695.1 KEGG: son:SO4740 hypothetical protein YP_752696.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_4692 methyl-accepting chemotaxis protein YP_752697.1 PFAM: PepSY-associated TM helix domain protein; KEGG: cps:CPS_4600 hypothetical protein YP_752698.1 PFAM: FMN-binding domain protein; KEGG: cps:CPS_4601 hypothetical protein YP_752699.1 PFAM: phosphate-selective porin O and P; KEGG: cps:CPS_4602 hypothetical protein YP_752700.1 KEGG: sde:Sde_2848 histidine kinase YP_752701.1 SMART: PUA domain containing protein; KEGG: son:SO1149 hypothetical SAM-dependent methyltransferase YP_752702.1 PFAM: protein of unknown function DUF805; KEGG: cps:CPS_3606 hypothetical protein YP_752703.1 PFAM: protein of unknown function DUF450; KEGG: vpa:VPA1572 hypothetical protein YP_752704.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_752705.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: son:SO4742 transcriptional regulator, DeoR family YP_752706.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4743 TonB-dependent receptor, putative YP_752707.1 KEGG: son:SO4745 glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_752708.1 TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: H+transporting two-sector ATPase, delta/epsilon subunit; KEGG: son:SO4746 ATP synthase F1, epsilon subunit YP_752709.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_752710.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_752711.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_752712.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_752713.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_752714.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_752715.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_752716.1 PFAM: ATP synthase I chain; KEGG: son:SO4754 ATP synthase protein I YP_752717.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: son:SO4755 ParB family protein YP_752718.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO4756 ParA family protein YP_752719.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_752720.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_752721.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_752722.1 PFAM: putative esterase; KEGG: ppr:PBPRA0783 putative esterase YP_752723.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ppr:PBPRA0784 putative alcohol dehydrogenase class III YP_752724.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2053 transcriptional regulator, LysR family YP_752725.1 KEGG: vpa:VPA0793 DNA polymerase III epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_752726.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_752727.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: son:SO0004 inner membrane protein, 60 kDa YP_752728.1 PFAM: protein of unknown function DUF37; KEGG: son:SO0005 conserved hypothetical protein TIGR00278 YP_752729.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_752730.1 in Escherichia coli transcription of this gene is enhanced by polyamines