-- dump date 20120504_161812 -- class Genbank::CDS -- table cds_note -- id note YP_001312323.1 conjugal transfer system TraA; oriT nicking enzyme YP_001312324.1 KEGG: sme:SMa1798 Kup2 potassium uptake protein YP_001312325.1 PFAM: protein of unknown function DUF454; KEGG: sme:SMb20557 hypothetical protein YP_001312326.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20538 putative solute-binding protein YP_001312327.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20537 putative transcriptional regulator protein YP_001312328.1 KEGG: sme:SMb20536 hypothetical protein YP_001312329.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMb20535 putative dehydrogenase protein YP_001312330.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20534 hypothetical protein YP_001312331.1 KEGG: mlo:mll2216 hypothetical protein YP_001312332.1 PFAM: RES domain protein; KEGG: mlo:mll2215 hypothetical protein YP_001312333.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMa0719 hypothetical protein YP_001312334.1 PFAM: regulatory protein IclR; SMP-30/Gluconolaconase/LRE domain protein; Transcriptional regulator IclR; KEGG: sme:SMa0717 putative calcium binding transcriptional regulatory protein YP_001312335.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: sme:SMa0715 putative UDP-glucose 4-epimerase YP_001312336.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: atc:AGR_pAT_681 probable sugC protein YP_001312337.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0711 putative ABC transporter permease protein, MalFG family YP_001312338.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0710 putative ABC transporter, sugar permease protein YP_001312339.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMa0709 putative ABC sugar transport system sugar binding protein YP_001312340.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMa0708 putative isomerase YP_001312341.1 PFAM: dihydrodipicolinate synthetase; KEGG: sme:SMa0707 dihydrodipicolinate synthase, putative YP_001312342.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: sme:SMa0705 putative DgoK2 2-dehydro-3-deoxygalactonokinase YP_001312344.1 PFAM: short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; KR domain protein; KEGG: sme:SMb20511 short chain dehydrogenase YP_001312345.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMb20510 probable galactonate dehydratase protein YP_001312346.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20509 putative transcriptional regulator protein YP_001312347.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20508 putative ABC transporter periplasmic sugar-binding protein YP_001312348.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001312349.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001312350.1 KEGG: sme:SMb20504 putative ABC transporter periplasmic sugar-binding protein YP_001312351.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20503 putative sugar ABC transporter ATP-binding protein YP_001312352.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20502 putative sugar ABC transporter permease protein YP_001312353.1 PFAM: putative sugar-binding domain protein; KEGG: sme:SMb20501 putative transcriptional regulator protein YP_001312354.1 PFAM: aldo/keto reductase; KEGG: sme:SMb20500 putative aldoketo reductase protein YP_001312355.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20499 putative glycerol-3-phosphate dehydrogenase protein YP_001312356.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sme:SMb20498 hypothetical protein YP_001312357.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMb20497 putative L-xylulose kinase protein YP_001312358.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: sme:SMb20496 probable GMC oxidoreductase protein YP_001312359.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bja:bll5958 hypothetical protein YP_001312360.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ret:RHE_CH01008 hypothetical protein YP_001312361.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: sme:SMa1516 NADH dehydrogenase I chain H YP_001312362.1 TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sme:SMa1519 putative oxidoreductase YP_001312363.1 PFAM: CBS domain containing protein; KEGG: sme:SMa1521 hypothetical protein YP_001312364.1 PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMa1523 NADH dehydrogenase I chain G YP_001312365.1 TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: sme:SMa1525 NADH dehydrogenase I chain F YP_001312366.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: sme:SMa1526 NADH dehydrogenase I chain E YP_001312367.1 TIGRFAM: NADH dehydrogenase I, D subunit; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: sme:SMa1529 NADH dehydrogenase I chain D YP_001312368.1 TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sme:SMa1531 NADH dehydrogenase I chain C YP_001312369.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001312370.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; KEGG: sme:SMa1533 NADH dehydrogenase I chain A YP_001312371.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sme:SMa1535 NADH dehydrogenase I chain N YP_001312372.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sme:SMa1536 NuoM2 NADH-Ubiquinone/plastoquinone (complex I) oxidoreductase YP_001312373.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001312375.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001312376.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: sme:SMa1544 NADH dehydrogenase I chain K YP_001312377.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: sme:SMa1545 putative oxidoreductase YP_001312378.1 KEGG: rle:pRL100452 hypothetical protein YP_001312379.1 PFAM: class II aldolase/adducin family protein; KEGG: sme:SMb20490 putative L-fuculose phosphate aldolase protein YP_001312380.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMb20489 putative carbohydrate kinase protein YP_001312381.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20488 hypothetical protein YP_001312382.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20487 putative sugar ABC transporter permease protein YP_001312383.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20486 putative sugar ABC transporter permease protein YP_001312384.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20485 putative sugar ABC transporter ATP-binding protein YP_001312385.1 KEGG: sme:SMb20484 putative ABC transporter periplasmic sugar-binding protein YP_001312386.1 PFAM: regulatory protein LacI; KEGG: sme:SMb20483 putative catabolite repressor protein YP_001312387.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMb20482 hypothetical protein YP_001312388.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: sme:SMb20481 putative asparagine synthetase (glutamine amidotransferase) protein YP_001312389.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20480 putative transcriptional regulator protein YP_001312390.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20479 putative dipeptide ABC transporter ATP-binding protein YP_001312391.1 PFAM: binding-protein-dependent transport systems inner membrane component; ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb20478 putative dipeptide ABC transporter permease and ATP-binding protein YP_001312392.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20477 putative didpeptide ABC transporter permease protein YP_001312393.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb20476 putative ABC transporter periplasmic dipeptide-binding protein YP_001312395.1 KEGG: bur:Bcep18194_B1716 membrane protein-like YP_001312396.1 SMART: Rhodanese domain protein; KEGG: ret:RHE_CH02717 putative superoxide dismutase SodM-like protein YP_001312397.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: rle:RL3184 putative chromate transport protein YP_001312398.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bsu:BG10628 similar to glucose 1-dehydrogenase YP_001312399.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: rxy:Rxyl_0938 NAD-dependent epimerase/dehydratase YP_001312400.1 PFAM: basic membrane lipoprotein; KEGG: rxy:Rxyl_0155 basic membrane lipoprotein YP_001312401.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bsu:BG12350 simple sugar transport system ATP-binding protein YP_001312402.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20126 putative sugar ABC transporter permease protein YP_001312403.1 PFAM: inner-membrane translocator; KEGG: sma:SAV6654 putative sugar ABC transporter permease protein YP_001312404.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: bcl:ABC3205 inosine-uridine preferring nucleoside hydrolase YP_001312405.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: ppr:PBPRA2062 putstive inosine-uridine preferring nucleoside hydrolase family protein YP_001312406.1 PFAM: isochorismatase hydrolase; KEGG: chy:CHY_0679 isochorismatase family protein YP_001312407.1 PFAM: regulatory protein MarR; KEGG: mag:amb1485 transcriptional regulator YP_001312408.1 PFAM: protein of unknown function DUF1185; KEGG: mlo:mll4877 hypothetical protein YP_001312409.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: mlo:mlr4788 N-methylhydantoinase B YP_001312410.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: mlo:mlr4786 N-methylhydantoinase A (mikimopine-lactam hydrogenase) YP_001312411.1 PFAM: peptidase M42 family protein; KEGG: sme:SMb20466 hypothetical glucanase protein YP_001312412.1 KEGG: sme:SMb20465 hypothetical protein YP_001312413.1 KEGG: sme:SMb20464 hypothetical protein YP_001312414.1 PFAM: protein of unknown function DUF995; KEGG: sme:SMb20463 hypothetical protein YP_001312415.1 KEGG: sme:SMb20462 putative cellulase H precursor protein YP_001312416.1 PFAM: protein of unknown function DUF995; KEGG: sme:SMb20461 hypothetical protein YP_001312417.1 KEGG: sme:SMb20460 putative cellulose synthase protein YP_001312418.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb20459 putative UDP-glucose 4-epimerase protein YP_001312419.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: sme:SMb20458 putative dTDP-glucose 4,6-dehydratase protein YP_001312420.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMb20457 putative transcriptional regulator transcription regulator protein YP_001312421.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20456 putative dehydrogenasereductase protein YP_001312422.1 PFAM: regulatory protein TetR; KEGG: sme:SMb20455 putative transcriptional regulator protein YP_001312423.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMb20454 hypothetical protein YP_001312424.1 KEGG: sme:SMb20452 hypothetical protein YP_001312425.1 KEGG: sme:SMb20451 hypothetical protein YP_001312426.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sme:SMb20450 putative regulatory protein YP_001312427.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb20449 putative methyltransferase protein YP_001312428.1 KEGG: sme:SMb20448 hypothetical protein YP_001312429.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: sme:SMb20447 hypothetical protein YP_001312430.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001312431.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20445 putative alcohol dehydrogenase protein YP_001312432.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20444 hypothetical protein YP_001312433.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb20443 putative permease protein YP_001312434.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb20442 putative periplasmic solute-binding protein YP_001312435.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20441 putative transcriptional regulator protein YP_001312436.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20436 putative nitrate transporter protein YP_001312437.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001312438.1 TIGRFAM: Ectoine utilization protein EutE; PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: sme:SMb20435 hypothetical protein YP_001312439.1 TIGRFAM: Ectoine utilization protein EutD; PFAM: creatinase; peptidase M24; KEGG: sme:SMb20434 putative hydrolasepeptidase protein YP_001312440.1 putative cyclodeaminase YP_001312441.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_001312442.1 TIGRFAM: Ectoine utilization protein EutA; PFAM: Asp/Glu racemase; KEGG: sme:SMb20431 hypothetical arylmalonate decarboxylase protein YP_001312443.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; Ectoine/hydroxyectoine ABC transporter permease protein EhuD; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20430 putative amino acid ABC transporter permease protein YP_001312444.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; Ectoine/hydroxyectoine ABC transporter permease protein EhuC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20429 putative amino acid ABC transporter permease protein YP_001312445.1 TIGRFAM: Ectoine/hydroxyEctoine ABC transporter solute-binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMb20428 putative ABC transporter amino acid-binding protein YP_001312446.1 TIGRFAM: Ectoine/hydroxyectoine ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20427 putative amino acid ABC transporter ATP-binding protein YP_001312447.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMb20426 hypothetical transcriptional regulator protein YP_001312448.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMb20425 putative transcriptional regulator protein YP_001312449.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20424 putative succinate-semialdehyde dehydrogenase protein YP_001312450.1 PFAM: aminotransferase class-III; KEGG: sme:SMb20423 hypothetical protein YP_001312451.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20422 putative oxidoreductase protein YP_001312452.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMb20420 putative glutathione S-transferase protein YP_001312453.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001312454.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20418 probable glycerol-3-phosphate ABC transporter permease protein YP_001312455.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20417 probable glycerol-3-phosphate ABC transporter permease protein YP_001312456.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20416 probable ABC transporter periplasmic glycerol-3-phosphate-binding protein precursor YP_001312457.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb20415 putative oxidoreductase protein YP_001312458.1 KEGG: sme:SMb20414 hypothetical protein YP_001312459.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMb20410 putative glycine-betaine-binding protein YP_001312460.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20409 putative hydroxybutyrate dehydrogenase protein YP_001312461.1 PFAM: Acetone carboxylase gamma subunit; KEGG: sme:SMb20408 hypothetical protein YP_001312462.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: sme:SMb20407 putative N-methylhydantoinase, hydantoin utiliztion protein YP_001312463.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: sme:SMb20406 putative hydantoin utilization protein A YP_001312464.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: sme:SMb20405 putative transcriptional regulator protein YP_001312465.1 KEGG: sme:SMb20401 hypothetical protein YP_001312466.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001312467.1 KEGG: sme:SMb20400 hypothetical protein YP_001312468.1 KEGG: sme:SMb20399 hypothetical protein YP_001312469.1 PFAM: metallophosphoesterase; KEGG: sme:SMb20398 hypothetical protein YP_001312470.1 PFAM: ribulose bisphosphate carboxylase large chain; KEGG: sme:SMb20393 putative ribulose bisphosphate carboxylaseoxygenase, large subunit protein YP_001312471.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001312472.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20391 putative cellulose synthase catalytic subunit protein YP_001312473.1 KEGG: sme:SMb20390 hypothetical protein YP_001312474.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: sme:SMb20389 hypothetical protein YP_001312475.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20388 putative NADPH:quinone oxidoreductase protein YP_001312476.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMb20387 putative transcriptional regulator protein YP_001312477.1 KEGG: sme:SMb20386 hypothetical protein YP_001312478.1 KEGG: sme:SMb20385 hypothetical protein YP_001312479.1 PFAM: peptidase M19 renal dipeptidase; KEGG: sme:SMb20384 putative dipeptidase protein YP_001312480.1 KEGG: sme:SMb20383 putative ABC transporter periplasmic solute-binding protein YP_001312481.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20382 putative ABC transporter permease protein YP_001312482.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20381 putative ABC transporter permease protein YP_001312483.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20380 putative ABC transporter ATP-binding protein YP_001312484.1 PFAM: aminotransferase class-III; KEGG: sme:SMb20379 hypothetical protein YP_001312485.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20378 putative aldehyde dehydrogenase protein YP_001312486.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMb20377 putative translation initiation inhibitor protein YP_001312487.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMb20376 hypothetical protein YP_001312488.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20375 putative transcriptional regulator protein YP_001312489.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb20374 putative periplasmic substrate-binding protein YP_001312490.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb20373 hypothetical protein YP_001312491.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20372 hypothetical protein YP_001312492.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001312493.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20370 putative ATP-binding transport protein YP_001312494.1 PFAM: protein of unknown function DUF214; KEGG: sme:SMb20369 conserved hypothetical protein YP_001312495.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sme:SMb20368 hypothetical protein YP_001312496.1 PFAM: regulatory protein TetR; KEGG: sme:SMb20367 putative transcriptional regulator protein YP_001312497.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb20366 putative transcriptional regulator protein YP_001312498.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20365 putative ABC transporter iron-binding protein YP_001312499.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20364 putative iron ABC transporter permease protein YP_001312500.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20363 putative iron ABC transporter ATP-binding protein YP_001312501.1 PFAM: inositol monophosphatase; KEGG: sme:SMb20362 putative inositol monophosphatase protein YP_001312503.1 KEGG: rpb:RPB_4397 transport system permease protein YP_001312504.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sus:Acid_3006 short-chain dehydrogenase/reductase SDR YP_001312505.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: sme:SMb20361 putative ionic voltage-gated channel protein YP_001312506.1 KEGG: sme:SMb20360 hypothetical protein YP_001312507.1 KEGG: sme:SMb20359 hypothetical protein YP_001312508.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; histidine kinase A domain protein; KEGG: sme:SMb20358 putative regulatory protein YP_001312509.1 PFAM: response regulator receiver; KEGG: sme:SMb20357 putative histidine kinase protein YP_001312510.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMb20356 putative sensory histidine kinase protein YP_001312511.1 KEGG: sme:SMb20355 hypothetical protein YP_001312512.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb20353 putative oxidoreductase protein YP_001312513.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20352 probable sugar ABC transporter permease protein YP_001312514.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20351 probable sugar ABC transporter ATP-binding protein YP_001312515.1 KEGG: sme:SMb20350 hypothetical protein YP_001312516.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20349 probable ABC transporter sugar-binding protein YP_001312517.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: sme:SMb20348 hypothetical protein YP_001312518.1 PFAM: regulatory protein TetR; KEGG: sme:SMb20347 putative transcriptional regulator protein YP_001312519.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMb20346 putative efflux protein YP_001312520.1 PFAM: acriflavin resistance protein; KEGG: sme:SMb20345 putative efflux protein YP_001312521.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: sme:SMb20344 putative transcriptional regulator protein YP_001312522.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sme:SMb20343 isoquinoline 1-oxidoreductase, alpha ubunit YP_001312523.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMb20342 putative soquinoline 1-oxidoreductase beta subunit YP_001312524.1 KEGG: sme:SMb20341 hypothetical protein YP_001312526.1 KEGG: sme:SMb20340 hypothetical protein YP_001312527.1 KEGG: sme:SMb20339 hypothetical protein YP_001312528.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20338 putative efflux protein YP_001312529.1 PFAM: regulatory protein TetR; KEGG: sme:SMb20337 putative transcriptional regulator protein YP_001312530.1 KEGG: sme:SMb20336 hypothetical protein YP_001312531.1 PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: sme:SMb20335 hypothetical protein YP_001312532.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: sit:TM1040_3285 outer membrane autotransporter barrel YP_001312533.1 PFAM: protein of unknown function DUF323; KEGG: sme:SMb20334 hypothetical protein YP_001312534.1 KEGG: rle:RL2862 hypothetical protein YP_001312535.1 KEGG: sme:SMa0690 hypothetical protein YP_001312536.1 KEGG: rle:pRL110217 hypothetical protein YP_001312537.1 PFAM: sulfatase; KEGG: rba:RB3877 aryl-sulfate sulphohydrolase YP_001312538.1 KEGG: bja:bll4740 nonspecific acid phosphatase precursor YP_001312539.1 PFAM: response regulator receiver; KEGG: bch:Bcen2424_3199 two component transcriptional regulator, LuxR family YP_001312540.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: bja:blr4774 two-component response regulator YP_001312541.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMa0939 probable sensor histidine kinase of two-component system YP_001312542.1 KEGG: rle:RL1907 putative transmembrane protein YP_001312543.1 PFAM: YidE/YbjL duplication domain protein; KEGG: zmo:ZMO1681 aspartate:alanine antiporter YP_001312544.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: rle:RL1917 hypothetical protein YP_001312545.1 PFAM: protein of unknown function DUF58; KEGG: rle:RL1916 hypothetical protein YP_001312546.1 KEGG: reh:H16_A1606 hypothetical membrane associated protein YP_001312547.1 PFAM: von Willebrand factor type A; KEGG: reu:Reut_A2888 von Willebrand factor, type A YP_001312548.1 PFAM: von Willebrand factor type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rle:RL1913 putative transmembrane protein YP_001312549.1 KEGG: reh:H16_A1609 hypothetical membrane spanning protein YP_001312550.1 PFAM: sulfatase; KEGG: rba:RB9498 arylsulfatase YP_001312551.1 KEGG: sme:SMb20331 hypothetical protein YP_001312552.1 PFAM: oxidoreductase domain protein; KEGG: sme:SMb20330 probable trehalosemaltose utilization protein, function YP_001312553.1 PFAM: protein of unknown function DUF1037; KEGG: sme:SMb20329 probable ThuA protein, function YP_001312554.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20328 probable trehalosemaltose transporter ATP-binding protein YP_001312555.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20327 probable trehalosemaltose transporter permease protein YP_001312556.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20326 probable trehalosemaltose transporter permease protein YP_001312557.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20325 probable trehalosemaltose-binding protein YP_001312558.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20324 putative ThuR, regulatory protein for trehalosemaltose transport system YP_001312559.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20323 putative transcriptional regulator protein YP_001312560.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb20322 hypothetical protein YP_001312561.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20321 hypothetical protein YP_001312562.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb20320 hypothetical protein YP_001312563.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMb20319 hypothetical protein YP_001312564.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20318 putative sugar ABC transporter permease protein YP_001312565.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20317 putative sugar ABC transporter ATP-binding protein YP_001312566.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20316 putative ABC transporter periplasmic sugar-binding protein YP_001312567.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20315 putative sugar ABC transporter permease protein YP_001312568.1 PFAM: Dak kinase; KEGG: sme:SMb20314 putative dihydroxyacetone kinase protein YP_001312569.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: sme:SMb20313 putative dihydroxyacetone kinase protein YP_001312570.1 PFAM: Dak kinase; putative sugar-binding domain protein; KEGG: sme:SMb20312 putative transcriptional regulator protein YP_001312571.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: sme:SMb20307 putative dihydroxyacetone kinase protein YP_001312572.1 PFAM: transposase IS4 family protein; KEGG: nha:Nham_2758 transposase, IS4 YP_001312573.1 KEGG: sme:SMb20303 hypothetical protein YP_001312574.1 KEGG: rle:RL0552 hypothetical protein YP_001312575.1 KEGG: sme:SMb20302 hypothetical protein YP_001312576.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: sme:SMb20300 putative adenylate cyclase protein YP_001312577.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_001312578.1 PFAM: dihydrodipicolinate synthetase; KEGG: sme:SMb20298 hypothetical protein YP_001312579.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20297 putative permease protein YP_001312580.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb20296 putative permease protein YP_001312581.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb20295 putative ABC transporter periplasmic substrate-binding protein YP_001312582.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001312583.1 KEGG: sme:SMb20293 hypothetical protein YP_001312584.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: sme:SMb20292 hypothetical immunogenic protein YP_001312585.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20291 hypothetical protein transmembrane YP_001312586.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20290 putative transcriptional regulator protein YP_001312587.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMb20289 putative permease protein YP_001312588.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMb20288 hypothetical protein YP_001312589.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMb20287 hypothetical protein YP_001312590.1 PFAM: NAD/NADP octopine/nopaline dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: sme:SMb20286 hypothetical protein YP_001312591.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20285 putative transcriptional regulator protein YP_001312592.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20284 putative ABC transporter periplasmic spermidineputrescine-binding protein YP_001312593.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20283 probable spermidineputrescine ABC transporter permease protein YP_001312594.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20282 probable spermidineputrescine ABC transporter permease protein YP_001312595.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20281 probable spermidineputrescine ABC transporter ATP-binding protein YP_001312596.1 KEGG: sme:SMb20280 hypothetical protein YP_001312597.1 KEGG: sme:SMb20279 hypothetical protein YP_001312598.1 TIGRFAM: uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMb20278 hypothetical protein YP_001312599.1 PFAM: aminotransferase class-III; KEGG: sme:SMb20277 hypothetical protein YP_001312600.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMb20276 putative transcriptional regulator protein YP_001312601.1 PFAM: protein of unknown function DUF849; KEGG: sme:SMb20275 hypothetical protein YP_001312602.1 KEGG: sme:SMb20274 hypothetical protein YP_001312603.1 KEGG: sme:SMb20273 hypothetical protein YP_001312604.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20272 putative transporter protein YP_001312605.1 PFAM: OsmC family protein; KEGG: sme:SMb20271 putative redox protein YP_001312606.1 PFAM: proline racemase; KEGG: sme:SMb20270 putative proline racemase protein YP_001312607.1 PFAM: protein of unknown function DUF126; protein of unknown function DUF521; KEGG: sme:SMb20269 hypothetical protein YP_001312608.1 PFAM: proline racemase; KEGG: sme:SMb20268 putative proline racemase protein YP_001312609.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20267 putative D-amino acid dehydrogenase protein YP_001312610.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20266 putative amino acid ABC transporter ATP-binding protein YP_001312611.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20265 putative amino acid ABC transporter permease protein YP_001312612.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20264 putative amino acid ABC transporter permease protein YP_001312613.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMb20263 putative ABC transporter periplasmic amino acid-binding protein YP_001312614.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20262 putative semialdehyde dehydrogenase protein YP_001312615.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: sme:SMb20261 putative malate dehydrogenase protein YP_001312616.1 PFAM: protein of unknown function DUF1232; KEGG: sme:SMb20260 hypothetical protein YP_001312617.1 PFAM: peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; KEGG: sme:SMb20028 hypothetical protein YP_001312618.1 PFAM: dihydrodipicolinate synthetase; KEGG: sme:SMb20259 putative dihydrodipicolinate synthase protein YP_001312619.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20258 putative transcriptional regulator protein YP_001312620.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMb20257 putative adenylate cyclase protein YP_001312621.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMb20256 hypothetical protein YP_001312622.1 PFAM: protein of unknown function DUF1003; KEGG: sme:SMb20255 hypothetical protein YP_001312623.1 KEGG: sme:SMb20254 hypothetical protein YP_001312624.1 KEGG: sme:SMb20253 hypothetical protein YP_001312625.1 KEGG: sme:SMb20252 hypothetical protein YP_001312626.1 KEGG: sme:SMb20251 hypothetical protein YP_001312627.1 PFAM: Phosphoglycerate mutase; KEGG: sme:SMb20250 hypothetical protein YP_001312628.1 PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; KEGG: sme:SMb20249 myo-inositol-1-phosphate synthase YP_001312629.1 KEGG: sme:SMb20248 hypothetical protein YP_001312630.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb20247 putative oxidoreductase protein YP_001312631.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20246 putative oxidoreductase protein YP_001312632.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KR domain protein; KEGG: sme:SMb20245 putative NDP-glucose dehydrataseepimerase protein YP_001312633.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb20244 putative CDP-tyvelose-2-epimerase protein YP_001312634.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb20243 putative glycosyltransferase protein YP_001312635.1 KEGG: sme:SMb20242 hypothetical protein YP_001312636.1 KEGG: sme:SMb20241 hypothetical protein YP_001312637.1 KEGG: sme:SMb20240 hypothetical protein YP_001312638.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: sme:SMb20239 putative dTDP-glucose 4,6-dehydratase protein YP_001312639.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb20238 hypothetical protein YP_001312640.1 KEGG: mes:Meso_2789 hypothetical protein YP_001312641.1 KEGG: sme:SMb20236 hypothetical protein YP_001312642.1 KEGG: sme:SMb20229 probable nutrient deprivation-induced protein YP_001312643.1 KEGG: sme:SMb20228 putative nutrient deprivation-induced protein YP_001312644.1 KEGG: sme:SMb20227 probable nutrient deprivation-induced protein YP_001312645.1 KEGG: sme:SMb20226 hypothetical protein YP_001312646.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sme:SMb20225 probable osmotically inducible sensory protein YP_001312647.1 KEGG: mes:Meso_3515 hypothetical protein YP_001312649.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMb20222 hypothetical protein YP_001312650.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMb20219 putative response regulator protein YP_001312651.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMb20218 putative sensor histidine kinase protein YP_001312652.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMb20217 hypothetical protein YP_001312653.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMb20216 putative epoxide hydrolase protein YP_001312654.1 PFAM: ThiJ/PfpI domain protein; KEGG: sme:SMb20212 hypothetical protein YP_001312655.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20211 putative transcriptional regulator protein YP_001312656.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMb20210 putative oxidoreductase protein YP_001312657.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: sme:SMb20209 hypothetical protein YP_001312658.1 TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sme:SMb20208 probable pyrroloquinoline quinone synthesis protein E YP_001312659.1 PFAM: coenzyme PQQ synthesis D; KEGG: sme:SMb20207 putative pyrroloquinoline quinone synthesis protein D YP_001312660.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001312661.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001312662.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20203 probable transcriptional regulator protein YP_001312663.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001312664.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: sme:SMb20201 putative phosphoribulokinase protein YP_001312665.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001312666.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001312667.1 type III RuBisCO; involved in carbon fixation YP_001312668.1 PFAM: ribulose bisphosphate carboxylase small chain; KEGG: sme:SMb20197 putative ribulose-1,5-bisphosphate carboxylase small subunit protein YP_001312669.1 TIGRFAM: CbxX/CfqX monofunctional; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: sme:SMb20196 probable CbbX protein YP_001312670.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: sme:SMb20195 putative pentose-5-phosphate-3-epimerase protein YP_001312671.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMb20194 hypothetical protein YP_001312672.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001312673.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001312674.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb20185 putative ABC-2 type transport system permease protein YP_001312675.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20184 putative ABC transporter ATP-binding protein YP_001312676.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20183 putative ABC transporter ATP-binding protein YP_001312677.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20182 putative ABC transporter protein YP_001312678.1 KEGG: sme:SMb20181 putative ABC transporter periplasmic solute-binding protein YP_001312679.1 KEGG: sme:SMb20180 hypothetical protein YP_001312680.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: WD-40 repeat protein; KEGG: sme:SMb20179 hypothetical protein YP_001312681.1 KEGG: sme:SMb20178 hypothetical protein YP_001312682.1 KEGG: sme:SMb20177 hypothetical protein YP_001312683.1 KEGG: sme:SMb20176 hypothetical protein YP_001312684.1 SMART: extracellular solute-binding protein family 3; KEGG: sme:SMb20175 putative methanol oxidation protein YP_001312685.1 KEGG: sme:SMb20174 putative cytochrome c protein YP_001312686.1 PFAM: Pyrrolo-quinoline quinone; KEGG: sme:SMb20173 putative methanol dehydrogenase protein, large subunit YP_001312687.1 PFAM: cytochrome c class I; KEGG: sme:SMb20172 putative cytochrome c protein YP_001312688.1 TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; KEGG: sme:SMb20171 putative S-formylglutathione hydrolase protein YP_001312689.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20170 probable glutathione-dependent formaldehyde dehydrogenase protein YP_001312690.1 KEGG: sme:SMb20169 hypothetical protein YP_001312691.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMb20168 hypothetical protein YP_001312692.1 PFAM: Sulphur oxidation protein SoxZ; KEGG: sme:SMb20167 hypothetical protein YP_001312693.1 KEGG: sme:SMb20166 hypothetical protein YP_001312694.1 KEGG: sme:SMb20165 hypothetical protein YP_001312695.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMb20164 putative sensor histidine kinase protein YP_001312696.1 PFAM: domain of unknown function DUF1745; KEGG: sme:SMb20163 hypothetical protein YP_001312697.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMb20162 putative transcriptional regulator protein YP_001312698.1 KEGG: rpe:RPE_0841 hypothetical protein YP_001312699.1 KEGG: mlo:msl0999 hypothetical protein YP_001312700.1 PFAM: Dual specificity protein phosphatase; KEGG: sme:SMb20160 hypothetical protein YP_001312701.1 PFAM: inositol monophosphatase; KEGG: sme:SMb20159 putative inositol monophosphatase protein YP_001312702.1 KEGG: sme:SMb20158 hypothetical ABC transporter periplasmic solute-binding protein YP_001312703.1 KEGG: sme:SMb20157 hypothetical ABC transporter periplasmic solute-binding protein YP_001312704.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20156 putative ABC transporter ATP-binding protein YP_001312705.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20155 putative ABC transporter permease protein YP_001312706.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb20154 putative transcriptional regulator protein YP_001312707.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; PFAM: Na+cotransporter; KEGG: sme:SMb20153 hypothetical protein transmembrane YP_001312708.1 PFAM: metallophosphoesterase; KEGG: sme:SMb20152 hypothetical protein YP_001312709.1 KEGG: sme:SMb20151 hypothetical protein YP_001312710.1 PFAM: inositol monophosphatase; KEGG: sme:SMb20150 putative inositol monophosphatase protein YP_001312711.1 PFAM: alpha/beta hydrolase fold; KEGG: ret:RHE_CH02571 probable chloride peroxidase protein YP_001312712.1 PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: sme:SMa1814 putative dioxygenase YP_001312713.1 PFAM: DoxX family protein; KEGG: sme:SMa1817 hypothetical protein YP_001312714.1 PFAM: Amidohydrolase 3; KEGG: rle:pRL120453 putative transcriptional regulatory protein YP_001312715.1 PFAM: protein of unknown function DUF1427; KEGG: sme:SMa1820 hypothetical protein YP_001312716.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMa1821 hypothetical protein YP_001312717.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMa1822 hypothetical protein YP_001312718.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMa1823 hypothetical protein YP_001312719.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMa1825 hypothetical protein YP_001312720.1 PFAM: manganese containing catalase; KEGG: rba:RB10727 manganese-containing catalase YP_001312721.1 KEGG: sme:SMb20149 hypothetical protein YP_001312722.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20148 putative transcriptional regulator protein YP_001312723.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sme:SMb20147 putative alcohol dehydrogenase protein YP_001312724.1 TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; KEGG: sme:SMb20146 4-hydroxythreonine-4-phosphate dehydrogenase 2 YP_001312725.1 KEGG: sme:SMb20145 hypothetical protein YP_001312726.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb20144 putative ABC transporter oligopeptide-binding protein YP_001312727.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20143 putative oligopeptide ABC transporter permease protein YP_001312728.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20142 putative oligopeptide ABC transporter permease protein YP_001312729.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb20141 putative oligopeptide ABC transporter ATP-binding protein YP_001312730.1 PFAM: dihydrodipicolinate synthetase; KEGG: sme:SMb20140 putative dihydrodipicolinate synthase protein YP_001312731.1 PFAM: monooxygenase FAD-binding; KEGG: msm:MSMEG_5719 oxidoreductase YP_001312732.1 PFAM: secretion protein HlyD family protein; KEGG: mag:amb3998 multidrug resistance efflux pump YP_001312733.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20698 putative transport protein, similar to E. coli multidrug resistance protein EmrB YP_001312734.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: ret:RHE_CH01194 probable adenylate cyclase protein YP_001312735.1 PFAM: regulatory protein TetR; KEGG: cvi:CV0711 probable transcriptional regulator, TetR family YP_001312736.1 KEGG: sme:SMb20139 hypothetical protein YP_001312737.1 PFAM: beta-lactamase domain protein; KEGG: mes:Meso_3529 beta-lactamase-like YP_001312738.1 PFAM: amidohydrolase 2; KEGG: sme:SMb20138 hypothetical protein YP_001312739.1 PFAM: amidohydrolase 2; KEGG: sme:SMb20137 hypothetical protein YP_001312740.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: sme:SMb20136 hypothetical protein YP_001312741.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: sme:SMb20135 putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase protein YP_001312742.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMb20134 putative permease protein YP_001312743.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sme:SMb20133 hypothetical protein YP_001312744.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMb20132 probable aldehyde oxidase and xanthine dehydrogenase family protein transmembrane YP_001312745.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sme:SMb20131 putative oxidoreductase protein YP_001312746.1 PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: sme:SMb20130 putative dehydrogenase protein YP_001312747.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20129 putative transcriptional regulator protein YP_001312748.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMb20128 putative deaminase protein YP_001312749.1 PFAM: basic membrane lipoprotein; KEGG: sme:SMb20127 putative simple sugar transport system substrate-binding protein YP_001312750.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20126 putative sugar ABC transporter permease protein YP_001312751.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20125 putative sugar ABC transporter permease protein YP_001312752.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20124 putative sugar ABC transporter ATP-binding protein YP_001312753.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20123 putative transcriptional regulator protein YP_001312754.1 PFAM: PfkB domain protein; KEGG: dra:DR1525 carbohydrate kinase, PfkB family YP_001312755.1 PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: ctc:CTC02530 Cys/Met metabolism lyase (PLP-dependent) YP_001312756.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oih:OB0776 sugar ABC transporter permease YP_001312757.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oih:OB0775 sugar ABC transporter permease YP_001312758.1 PFAM: extracellular solute-binding protein family 1; KEGG: bcl:ABC0436 sugar ABC transporter substrate-binding protein YP_001312759.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: pmu:PM1714 hypothetical HI0143 YP_001312760.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: bja:bll8013 putative phosphoribosylanthranilate isomerase YP_001312761.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb20117 hypothetical sugar transferase protein YP_001312762.1 PFAM: Amylo-alpha-16-glucosidase; KEGG: sme:SMb20116 hypothetical protein YP_001312763.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001312764.1 PFAM: Dimethylmenaquinone methyltransferase; KEGG: sme:SMb20114 hypothetical protein YP_001312765.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMb20113 putative dehydrogenase protein YP_001312766.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMb20112 hypothetical protein YP_001312767.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb20111 putative oligopeptide ABC transporter ATP-binding protein YP_001312768.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20110 putative oligopeptide ABC transporter permease protein YP_001312769.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20109 putative oligopeptide ABC transporter permease protein YP_001312770.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb20108 putative ABC transporter periplasmic oligopeptide-binding protein YP_001312771.1 KEGG: sme:SMb20107 hypothetical protein YP_001312772.1 PFAM: regulatory protein GntR HTH; protein of unknown function UPF0074; GntR domain protein; KEGG: sme:SMb20106 putative transcriptional regulator protein YP_001312773.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20105 putative transcriptional regulator protein YP_001312774.1 KEGG: sme:SMb20103 putative monooxygenase protein YP_001312775.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_L_281 hypothetical protein YP_001312776.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: sme:SMb20102 putative acetoin catabolism regulatory protein YP_001312777.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001312778.1 KEGG: sme:SMb20100 putative dehydrogenase protein YP_001312779.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMb20099 putative trehalose synthase protein YP_001312780.1 PFAM: protein of unknown function DUF1362; KEGG: sme:SMb20098 hypothetical protein YP_001312781.1 PFAM: molybdopterin dehydrogenase FAD-binding; FAD linked oxidase domain protein; D-arabinono-14-lactone oxidase; KEGG: sme:SMb20097 hypothetical oxidoreductase protein YP_001312782.1 PFAM: protein of unknown function DUF1362; KEGG: sme:SMb20096 hypothetical protein YP_001312783.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sme:SMb20095 putative pyruvate oxidase protein YP_001312784.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sme:SMb20094 putative phospholipase protein YP_001312785.1 KEGG: sme:SMb20093 hypothetical protein YP_001312786.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMb20092 hypothetical protein YP_001312787.1 PFAM: protein of unknown function DUF892; KEGG: sme:SMb20091 hypothetical protein YP_001312788.1 KEGG: sme:SMb20089 hypothetical protein YP_001312789.1 TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; Erythromycin esterase; KEGG: sme:SMb20088 hypothetical fusion protein YP_001312790.1 KEGG: sme:SMb20087 hypothetical protein YP_001312792.1 PFAM: protein of unknown function DUF1328; KEGG: sme:SMb20084 hypothetical protein transmembrane YP_001312794.1 KEGG: sme:SMb20083 hypothetical protein YP_001312795.1 KEGG: sme:SMb20082 hypothetical protein YP_001312796.1 PFAM: metallophosphoesterase; KEGG: sme:SMb20081 hypothetical protein YP_001312797.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMb20080 putative alcohol dehydrogenase protein YP_001312798.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMb20079 putative hemolysin-adenlyate cyclase protein YP_001312799.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMb20078 putative nitratenitrite response regulator protein YP_001312800.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sme:SMb20077 putative sensor histidine kinase protein YP_001312801.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20076 short chain dehydrogenase YP_001312802.1 KEGG: sme:SMb20075 hypothetical protein YP_001312803.1 KEGG: sme:SMb20074 hypothetical protein YP_001312804.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20073 putative oxidoreductase protein YP_001312805.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20072 putative rhizopine binding protein YP_001312806.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20071 putative efflux protein YP_001312807.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sme:SMb20070 putative sulfate permease protein YP_001312808.1 PFAM: major facilitator superfamily MFS_1; KEGG: mes:Meso_1534 major facilitator superfamily MFS_1 YP_001312809.1 PFAM: protein of unknown function DUF1458; KEGG: sme:SMb20068 hypothetical protein YP_001312810.1 PFAM: intradiol ring-cleavage dioxygenase; KEGG: sme:SMb21380 putative dioxygenase, slightly similar to catechol 1,2-dioxygenase protein YP_001312811.1 KEGG: sme:SMb20066 hypothetical protein YP_001312812.1 KEGG: ret:RHE_CH02153 hypothetical protein YP_001312813.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: rru:Rru_A2242 glutathione-dependent formaldehyde-activating, GFA YP_001312814.1 KEGG: sme:SMb20065 hypothetical protein YP_001312815.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMa0376 putative hydrolase YP_001312816.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_L_1752 hypothetical protein YP_001312817.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: atc:AGR_L_1754 hypothetical protein YP_001312818.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb20059 hypothetical protein YP_001312819.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20058 putative ABC transporter ATP-binding protein YP_001312820.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: sme:SMb20057 putative ABC transporter permease protein YP_001312821.1 PFAM: periplasmic binding protein; KEGG: sme:SMb20056 putative ABC transporter periplasmic solute-binding protein YP_001312823.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMb20055 putative transcriptional regulator protein YP_001312824.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMb20054 putative non-heme chloroperoxidase protein YP_001312825.1 KEGG: sme:SMb20050 hypothetical protein YP_001312826.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001312827.1 PFAM: UbiC transcription regulator-associated domain protein; KEGG: sme:SMb20048 putative transcriptional regulator protein YP_001312828.1 KEGG: sme:SMb20047 hypothetical protein YP_001312829.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMb20046 probable replication protein A YP_001312830.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; RepB plasmid partition; KEGG: sme:SMb20045 probable replication protein B YP_001312831.1 PFAM: replication protein C; KEGG: sme:SMb20044 probable replication protein C YP_001312832.1 KEGG: sme:SMb20043 hypothetical protein YP_001312833.1 PFAM: protein of unknown function DUF1612; KEGG: sme:SMb20042 hypothetical protein YP_001312834.1 KEGG: sme:SMb20041 hypothetical protein YP_001312835.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMb20040 hypothetical protein transmembrane YP_001312836.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMb20039 putative transcriptional regulator protein YP_001312837.1 KEGG: sme:SMb20032 hypothetical protein YP_001312838.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001312839.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMb20029 hypothetical protein YP_001312840.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: rsp:RSP_7395 transcriptional regulator, MerR family YP_001312841.1 KEGG: bur:Bcep18194_A5272 hypothetical protein YP_001312842.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: sme:SMb20027 hypothetical protein YP_001312843.1 PFAM: protein of unknown function DUF1468; KEGG: sme:SMb20026 hypothetical protein YP_001312844.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20025 hypothetical protein YP_001312845.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sme:SMb20024 pseudouridylate synthase YP_001312846.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: sme:SMb20023 N-methylhydantoinase / 5-oxoprolinase (ATP-hydrolysing) YP_001312847.1 PFAM: dienelactone hydrolase; KEGG: sme:SMb20022 hypothetical protein YP_001312849.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMb20021 putative transcriptional regulator protein YP_001312850.1 PFAM: dehydrogenase E1 component; Transketolase central region; Transketolase domain protein; KEGG: sme:SMb20020 putative pyruvate dehydrogenase E1 component,alpha and beta subunits protein YP_001312851.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sme:SMb20019 putative dihydrolipoamide succinyltransferase protein YP_001312852.1 KEGG: sme:SMb20018 putative sugar ABC transporter periplasmic sugar-binding protein ABC transporter YP_001312853.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20017 putative sugar ABC transporter ATP-binding protein ABC transporter YP_001312854.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20016 putative sugar ABC transporter permease protein ABC transporter YP_001312855.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20015 putative sugar ABC transporter permease protein ABC transporter YP_001312856.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20014 putative transcriptional regulator protein YP_001312857.1 PFAM: oxidoreductase domain protein; KEGG: sme:SMb20013 hypothetical protein YP_001312859.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Vitamin K epoxide reductase; Male sterility domain; KEGG: sme:SMb20012 hypothetical protein YP_001312860.1 PFAM: zinc/iron permease; KEGG: sme:SMb20011 zinc transporter, ZIP family YP_001312861.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth YP_001312862.1 PFAM: Catalase domain protein; KEGG: sme:SMb20007 probable catalase C protein YP_001312863.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: sme:SMb20006 hypothetical protein YP_001312864.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMb20005 putative glutathione S-transferase protein YP_001312865.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20004 putative GstR-like transcriptional regulator protein YP_001312866.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001312867.1 KEGG: sme:SMa1635 hypothetical protein YP_001312868.1 KEGG: sme:SMa0121 hypothetical protein YP_001312869.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia and high GC gram-positive bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the R. leguminosarum protein in this cluster is transcribed under anaerobic conditions and is not necessary for growth YP_001312870.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20002 probable lactose transport ATP-binding protein YP_001312871.1 PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: sme:SMb21655 probable beta-galactosidase protein YP_001312872.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21654 probable lactose uptake ABC transporter permease protein YP_001312873.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21653 probable lactose uptake ABC transporter permease protein YP_001312874.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21652 probable lactose uptake ABC transporter periplasmic solute-binding protein precursor YP_001312875.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21650 putative transcriptional regulator, LacI family protein YP_001312876.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: sme:SMb21649 alpha-galactoside utilization transcriptional regulator, AraC family protein YP_001312877.1 PFAM: glycoside hydrolase family 4; KEGG: sme:SMb21648 alpha-galactosidase (melibiase) protein YP_001312878.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb21647 alpha-galactoside ABC transporter periplasmic solute-binding protein precursor YP_001312879.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21646 putative ABC transporter permease protein YP_001312880.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21645 putative ABC transporter permease protein YP_001312881.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21644 putative ABC transporter ATP-binding protein YP_001312882.1 PFAM: glycoside hydrolase family 4; KEGG: sme:SMb21643 probable alpha-galactosidase (melibiase) protein YP_001312883.1 PFAM: protein of unknown function DUF992; KEGG: sme:SMb21642 hypothetical protein YP_001312884.1 TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: sme:SMb21641 putative regulator of phenylacetic acid degradation, ArsR family protein YP_001312885.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001312886.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001312887.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: sme:SMb21638 putative phenylacetic acid degradation protein YP_001312888.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: sme:SMb21637 putative phenylacetic acid degradation protein YP_001312889.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMb21636 putative ferredoxin reductase electron transfer component protein YP_001312890.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001312891.1 PFAM: thioesterase superfamily protein; KEGG: sme:SMb21634 putative acyl-CoA thioester hydrolase protein YP_001312892.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001312893.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: sme:SMb21632 putative 3-hydroxyacyl-CoA dehydrogenase protein YP_001312894.1 TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: sme:SMb21631 putative carboxynorspermidine decarboxylase protein YP_001312895.1 PFAM: Saccharopine dehydrogenase; KEGG: sme:SMb21630 hypothetical protein YP_001312896.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rle:RL4378 putative LacI family transcriptional regulator YP_001312897.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20634 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001312898.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20633 putative sugar uptake ABC transporter permease protein YP_001312899.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20632 putative sugar uptake ABC transporter permease protein YP_001312900.1 PFAM: protein of unknown function DUF1680; KEGG: sme:SMb20631 hypothetical protein YP_001312901.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20630 putative sugar uptake ABC transporter ATP-binding protein YP_001312902.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001312903.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rle:RL2856 putative transmembrane lysine/arginine export protein YP_001312904.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: mlo:mll6377 threonine efflux protein YP_001312905.1 PFAM: dihydrodipicolinate synthetase; KEGG: mlo:mll6376 dihydrodipicolinate synthetase YP_001312906.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMb20626 putative transcriptional regulator, AraC family protein YP_001312907.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20625 drug:H+ antiporter-1, DHA1 family YP_001312908.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001312909.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001312910.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001312911.1 TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20616 putative thiamine biosynthesis oxidoreductase protein YP_001312912.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001312913.1 KEGG: sme:SMb20614 hypothetical protein YP_001312914.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sme:SMb20613 C4-dicarboxylate transport transcriptional regulatory protein YP_001312915.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMb20612 C4-dicarboxylate transport sensor protein YP_001312916.1 involved in the transport of C4-dicarboxylates across the membrane YP_001312917.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMb20610 putative two-component response regulator protein YP_001312918.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMb20609 putative two-component sensor histidine kinase protein YP_001312919.1 PFAM: regulatory protein ArsR; KEGG: sme:SMb20608 putative transcriptional regulator, ArsR family protein YP_001312920.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMb20607 hypothetical protein YP_001312921.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMb20606 hypothetical protein YP_001312922.1 KEGG: sme:SMb20605 putative ureashort-chain amide or branched-chain amino acid uptake ABC transporter periplasmic solute-binding protein precursor YP_001312923.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20604 putative ureashort-chain amide or branched-chain amino acid uptake ABC transporter permease protein, possibly fusion protein YP_001312924.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20603 putative ureashort-chain amide or branched-chain amino acid uptake ABC transporter permease protein YP_001312925.1 PFAM: ABC transporter related; KEGG: sme:SMb20602 putative ureashort-chain amide or branched-chain amino acid uptake ABC transporter ATP-binding protein YP_001312926.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21707 putative ureashort-chain amide or branched-chain amino acid uptake ABC transporter ATP-binding protein YP_001312927.1 KEGG: sme:SMb20600 hypothetical protein YP_001312928.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; RepB plasmid partition; KEGG: sme:SMb20599 putative smb01f11-replication protein YP_001312929.1 PFAM: regulatory protein MerR; Cobyrinic acid ac-diamide synthase; KEGG: sme:SMb20598 probable replication protein YP_001312930.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: atc:AGR_L_2979 hypothetical protein YP_001312931.1 PFAM: protein of unknown function DUF949; KEGG: atc:AGR_L_2977 hypothetical protein YP_001312932.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: sme:SMb20595 putative cell division protein FtsK like protein YP_001312933.1 PFAM: blue (type 1) copper domain protein; KEGG: sme:SMb20594 putative amicyanin precursor protein YP_001312934.1 KEGG: sme:SMb20593 hypothetical protein YP_001312935.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001312936.1 catalyzes the hydrolysis of acylphosphate YP_001312937.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: sme:SMb20585 putative gamma-glutamyltranspeptidase protein YP_001312938.1 PFAM: oxidoreductase molybdopterin binding; KEGG: sme:SMb20584 hypothetical protein YP_001312939.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: rle:RL3904 putative AraC family transcriptional regulator for P-hydroxybenzoate hydroxylase YP_001312940.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001312941.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20582 putative transcriptional regulator, LysR family protein YP_001312942.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20581 putative 4-hydroxyphenylpyruvate dioxygenase protein YP_001312943.1 TIGRFAM: pca operon transcription factor PcaQ; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20580 putative transcriptional activator of the pca operon, LysR family protein YP_001312944.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; Ndr family protein; KEGG: sme:SMb20579 putative beta-ketoadipate enol-lactone hydrolase protein YP_001312945.1 TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMb20578 putative gamma carboxymuconolactone decarboxylase protein YP_001312946.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: sme:SMb20577 protocatechuate 3,4-dioxygenase, beta subunit YP_001312947.1 TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: sme:SMb20576 putative protocatechuate 3,4-dioxygenase alpha chain protein YP_001312948.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_001312949.1 KEGG: sme:SMb20574 putative maltooligosyl trehalose synthase protein; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_001312950.1 PFAM: NADPH-dependent FMN reductase; KEGG: sme:SMb20573 putative NADH-dependent FMN reductase protein YP_001312951.1 KEGG: sme:SMb21691 putative nitrilotriacetate monooxygenase component A protein YP_001312952.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20571 putative aliphatic sulfonate uptake ABC transporter permease protein YP_001312953.1 PFAM: NMT1/THI5 like domain protein; KEGG: sme:SMb20570 putative aliphatic sulfonates uptake ABC transporter periplasmic solute-binding protein precursor YP_001312954.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20569 putative ABC transporter ATP-binding protein YP_001312955.1 PFAM: Extracellular ligand-binding receptor; KEGG: sme:SMb20568 putative amino acid uptake ABC transporter solute-binding protein, LeuIle/Val-binding protein family YP_001312956.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20787 putative branched-chain amino acid uptake ABC transporter permease protein YP_001312957.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20786 putative branched-chain amino acid uptake ABC transporter permease protein YP_001312958.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20785 putative branched-chain amino acid uptake ABC transporter ATP-binding protein YP_001312959.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20784 putative branched-chain amino acid uptake ABC transporter ATP-binding protein YP_001312960.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20773 putative transcriptional regulator, GntR family protein YP_001312961.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001312962.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20771 hypothetical protein YP_001312963.1 KEGG: sme:SMb20770 hypothetical protein YP_001312964.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: sme:SMb20769 hypothetical protein YP_001312965.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20768 hypothetical protein YP_001312966.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_001312967.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sme:SMb20765 putative acetyltransferase protein YP_001312968.1 TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20764 putative phosphonate uptake ABC transporter ATP-binding protein YP_001312969.1 TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20763 putative phosphonate uptake ABC transporter ATP-binding protein YP_001312970.1 PFAM: phosphonate metabolism PhnJ; KEGG: sme:SMb20762 putative C-P (carbon-phosphorus) lyase component protein YP_001312971.1 PFAM: phosphonate metabolism; KEGG: sme:SMb20761 putative C-P (carbon-phosphorus) lyase component protein YP_001312972.1 PFAM: phosphonate metabolism; KEGG: sme:SMb20760 putative C-P (carbon-phosphorus) lyase component protein YP_001312973.1 PFAM: phosphonate metabolism PhnG; KEGG: sme:SMb20759 putative C-P (carbon-phosphorus lyase component protein YP_001312974.1 TIGRFAM: phosphonates metabolism transcriptional regulator PhnF; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMb20758 putative transcriptional regulator, GntR or ArsR family protein YP_001312975.1 MDM; functions in conversion of succinate to propionate YP_001312976.1 PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: sme:SMb20756 putative propionyl-CoA carboxylase alpha chain protein YP_001312977.1 PFAM: carboxyl transferase; KEGG: sme:SMb20755 putative propionyl-CoA carboxylase beta chain protein YP_001312978.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: sme:SMb20754 hypothetical protein YP_001312979.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMb20753 putative acyl-CoA dehydrogenase protein YP_001312980.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001312981.1 TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMb20751 putative 3-hydroxyisobutyrate dehydrogenase protein YP_001312982.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20750 putative dehydrogense, possibly gluconate 5-dehydrogenase protein YP_001312983.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sme:SMb20749 putative D-mannonate oxidoreductase protein YP_001312984.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20748 putative glycosyltransferase protein YP_001312985.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rxy:Rxyl_2600 transcriptional regulator, LacI family YP_001312986.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc00340 putative oxidoreductase protein YP_001312987.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMb20747 hypothetical enzyme, haloacid dehalogenaseepoxide hydrolase family protein YP_001312988.1 KEGG: sme:SMb20746 hypothetical protein YP_001312989.1 PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sme:SMb20745 putative glutatmine synthetase II protein YP_001312990.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: atc:AGR_pAT_528 hypothetical protein YP_001312991.1 KEGG: xcb:XC_1509 hypothetical protein YP_001312992.1 KEGG: sme:SMb20727 hypothetical protein YP_001312993.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: sme:SMb20726 conserved hypothetical membrane protein YP_001312994.1 KEGG: sme:SMb20725 putative tricarboxylic transport membrane protein YP_001312995.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20724 putative tricarboxylic transport membrane protein YP_001312996.1 KEGG: sme:SMb20723 putative iron ABC transporter periplasmic solute-binding protein precursor YP_001312997.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMb20722 putative two-component response regulator protein YP_001312998.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: sme:SMb20721 putative two-component sensor histidine kinase protein YP_001312999.1 KEGG: sme:SMb20720 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313000.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20719 putative sugar uptake ABC transporter permease protein YP_001313001.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20718 putative sugar uptake ABC transporter ATP-binding protein YP_001313002.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20717 putative transcriptional regulator, LacI family protein YP_001313004.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20714 putative sugar uptake ABC transporter permease protein YP_001313005.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20713 putative sugar uptake ABC transporter ATP-binding protein YP_001313006.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20712 putative rhizopine uptake ABC transporter periplasmic solute-binding protein precursor YP_001313007.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20711 putative Ioli protein YP_001313008.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMb20710 putative dehydrogenase protein YP_001313009.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_001313010.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: sme:SMb20708 putative methylated-DNA--protein-cysteine methyltransferase YP_001313011.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMb20707 putative adenylate cyclase protein YP_001313012.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMb20706 putative amino acid uptake ABC transporter periplasmic solute-binding protein precursor YP_001313013.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMb20705 hypothetical protein YP_001313014.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001313015.1 PFAM: PEBP family protein; KEGG: sme:SMb20703 hypothetical protein YP_001313016.1 TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; PAS fold domain protein; KEGG: rpa:RPA3316 possible chemotaxis cheB/cheR fusion protein YP_001313017.1 PFAM: response regulator receiver; KEGG: ret:RHE_PF00072 probable two-component response regulator protein YP_001313018.1 PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; KEGG: sme:SMb20702 putative regulatory protein, possibly two-component response regulator YP_001313019.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: sme:SMb20701 hypothetical protein YP_001313020.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMb20700 hypothetical protein YP_001313021.1 PFAM: secretion protein HlyD family protein; KEGG: sme:SMb20699 putative protein secretion protein, HlyD family, similar to E. coli EmrK YP_001313022.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20698 putative transport protein, similar to E. coli multidrug resistance protein EmrB YP_001313023.1 PFAM: peptidase M20; KEGG: sme:SMb20697 putative peptidase, similar to arginine utilization protein RocB YP_001313024.1 PFAM: extracellular solute-binding protein family 1; KEGG: rde:RD1_3953 sugar ABC transporter, substrate-binding domain, putative YP_001313025.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3700 binding-protein-dependent transport systems inner membrane component YP_001313026.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_3950 putative sugar ABC transporter, permease protein YP_001313027.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rde:RD1_3954 sugar ABC transporter, ATP-binding protein, putative YP_001313028.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001313030.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rde:RD1_3945 dehydrogenase YP_001313031.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: rde:RD1_3944 transcriptional regulatory protein, LacI family, putative YP_001313032.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: rde:RD1_3942 cupin domain protein YP_001313033.1 KEGG: rde:RD1_3940 hypothetical protein YP_001313034.1 PFAM: Amidase; KEGG: syg:sync_2679 enantiomer-selective amidase YP_001313035.1 PFAM: alpha/beta hydrolase fold; KEGG: rpb:RPB_4141 alpha/beta hydrolase protein YP_001313036.1 PFAM: protein of unknown function DUF1486; KEGG: jan:Jann_4086 hypothetical protein YP_001313037.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMb20689 probable exodeoxyribonuclease III protein YP_001313038.1 KEGG: sme:SMb20688 hypothetical protein YP_001313039.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMb20687 hypothetical protein YP_001313040.1 TIGRFAM: Ku family containing protein; PFAM: Ku domain protein; KEGG: sme:SMb20686 putative ATP-dependent DNA ligase protein YP_001313041.1 TIGRFAM: DNA ligase D; DNA ligase D 3'-phosphoesterase domain; DNA polymerase LigD polymerase domain; DNA polymerase LigD ligase region; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sme:SMb20685 hypothetical protein YP_001313042.1 PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: sme:SMb20684 hypothetical protein YP_001313043.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20683 putative transcriptional regulator, LysR family protein YP_001313044.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMc04171 putative hemolysin-type calcium-binding protein YP_001313045.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMb20682 putative acetate operon repressor IclR protein YP_001313046.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001313047.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20680 putative hydroxypyruvate isomerase protein YP_001313048.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMb20679 putative tartronate semialdehyde reductase protein YP_001313049.1 PFAM: MOFRL domain protein; KEGG: sme:SMb20678 putative hydroxypyruvate reductase protein YP_001313050.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001313051.1 PFAM: protein of unknown function DUF930; KEGG: sme:SMb20676 hypothetical protein YP_001313052.1 PFAM: protein of unknown function DUF1349; KEGG: sme:SMb20675 hypothetical protein YP_001313053.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20674 putative transcriptional regulator, LacI family protein YP_001313054.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20673 putative sugar uptake ABC transporter ATP-binding protein YP_001313055.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20672 putative sugar uptake ABC transporter permease protein YP_001313056.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20671 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313057.1 PFAM: type III effector Hrp-dependent outers; KEGG: sme:SMb20670 hypothetical protein YP_001313058.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb20669 conserved hypothetical protein, possibly hydroxypyruvate isomerase YP_001313059.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: sme:SMb20668 3-hydroxyisobutyrate dehydrogenase YP_001313060.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20667 putative transcriptional regulator, LacI family protein YP_001313061.1 PFAM: class II aldolase/adducin family protein; KEGG: sme:SMb20666 hypothetical protein YP_001313062.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb20664 putative transcriptional regulator, GntR family protein YP_001313063.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb20663 hypothetical protein YP_001313064.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20662 putative oxidoreductase protein YP_001313065.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20661 putative sugar uptake ABC transporter ATP-binding protein YP_001313066.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20660 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313067.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20659 putative sugar uptake ABC transporter permease protein YP_001313068.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20658 putative sugar uptake ABC transporter permease protein YP_001313069.1 KEGG: sme:SMb20657 hypothetical membrane protein YP_001313070.1 PFAM: aldo/keto reductase; KEGG: sme:SMb20656 putative oxidoreductase protein YP_001313071.1 KEGG: sme:SMb20654 hypothetical protein YP_001313072.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: sme:SMb20652 putative asparagine synthetase protein YP_001313073.1 KEGG: sme:SMb20651 hypothetical protein YP_001313074.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMb20650 putative long-chain fatty-acid-CoA ligase protein YP_001313075.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001313077.1 KEGG: sme:SMb20647 hypothetical protein YP_001313078.1 blocks the formation of polar Z-ring septums YP_001313079.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMb21523 putative cell division inhibitor protein YP_001313080.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001313081.1 KEGG: sme:SMb21521 hypothetical exported protein, glycine-rich YP_001313082.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMb21520 putative two-component response regulator protein YP_001313083.1 PFAM: ATP-binding region ATPase domain protein; KEGG: sme:SMb21519 putative two-component sensor histidine kinase protein YP_001313084.1 KEGG: sme:SMb21518 hypothetical protein YP_001313085.1 PFAM: EAL domain protein; KEGG: sme:SMb21517 hypothetical protein YP_001313086.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMb21516 hypothetical protein YP_001313087.1 KEGG: sme:SMb21515 hypothetical protein YP_001313088.1 TIGRFAM: modification methylase, HemK family; PFAM: putative RNA methylase; methyltransferase small; KEGG: sme:SMb21514 putative modification methylase protein YP_001313089.1 PFAM: polysaccharide biosynthesis protein; KEGG: sme:SMb21513 putative cell-surface polysaccharide exporter protein, PST family YP_001313090.1 KEGG: sme:SMb21512 hypothetical membrane protein YP_001313091.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: sme:SMb21506 putative auxiliar protein involved in export of cell surface polysaccharides, MPA1 family without cytosolic domain, slightly ExoP-like YP_001313092.1 PFAM: O-antigen polymerase; KEGG: sme:SMb21505 putative membrane protein, similar to Wzy-like polysaccharide polymerase ExoQ YP_001313093.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMb21504 putative protein, slightly similar to carbohydrate deacetylase YP_001313094.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21503 putative glycosyltransferase protein YP_001313095.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: sme:SMb21502 putative glycosyltransferase protein YP_001313096.1 KEGG: sme:SMb21501 hypothetical membrane protein YP_001313097.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb21500 putative glycosyltransferase protein YP_001313098.1 KEGG: sme:SMb21499 hypothetical protein YP_001313099.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sme:SMb21498 putative acriflavin resistence protein YP_001313100.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMb21497 putative acriflavin resistance protein YP_001313101.1 KEGG: sme:SMa0034 possible protease YP_001313102.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMb21493 putative transcriptional regulator, AsnC family protein YP_001313103.1 PFAM: protein of unknown function DUF922; KEGG: sme:SMb21492 hypothetical protein YP_001313104.1 PFAM: protein of unknown function DUF992; KEGG: sme:SMb21491 hypothetical protein YP_001313105.1 PFAM: Surfeit locus 1 family protein; KEGG: rle:pRL110038 putative surfeit locus protein 1 YP_001313106.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: rle:pRL110039 putative cytochrome o ubiquinol oxidase protein CyoD YP_001313107.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMb21489 putative cytochrome o ubiquinol oxidase chain III protein YP_001313108.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome c oxidase subunit I; KEGG: sme:SMb21488 putative cytochrome o ubiquinol oxidase chain I protein YP_001313109.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: sme:SMb21487 putative cytochrome o ubiquinol oxidase chain II protein YP_001313110.1 PFAM: General substrate transporter; KEGG: sme:SMb21486 putative metabolite transport protein YP_001313111.1 KEGG: rsp:RSP_0947 hypothetical protein YP_001313112.1 KEGG: sme:SMb21687 hypothetical protein YP_001313113.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMb21484 putative RNA polymerase sigma-E factor (sigma-24) protein YP_001313114.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMb21483 hypothetical protein YP_001313115.1 KEGG: sme:SMb21482 hypothetical protein YP_001313116.1 PFAM: CBS domain containing protein; KEGG: sme:SMb21481 hypothetical protein YP_001313117.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21480 hypothetical protein YP_001313118.1 KEGG: sme:SMb21479 hypothetical protein YP_001313119.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001313120.1 KEGG: sme:SMb21473 hypothetical protein YP_001313121.1 PFAM: protein of unknown function DUF1452; KEGG: sme:SMb21472 hypothetical protein YP_001313122.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21471 hypothetical protein YP_001313123.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21470 hypothetical protein YP_001313124.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21469 hypothetical protein YP_001313125.1 PFAM: protein of unknown function DUF475; KEGG: sme:SMb21468 hypothetical protein YP_001313126.1 KEGG: sme:SMb21467 hypothetical protein YP_001313127.1 TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21466 ABC transporter ATP-binding protein YP_001313128.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: sme:SMb21465 protein secretion protein, HlyD family YP_001313129.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMb21464 putative transcriptional regulator, gntR family protein YP_001313130.1 PFAM: glycoside hydrolase family 4; KEGG: sme:SMb21463 putative glycosyl hydrolase, probable 6-phospho-beta-glucosidases protein YP_001313131.1 PFAM: PfkB domain protein; KEGG: sme:SMb21462 putative sugar kinase protein YP_001313132.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21461 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313133.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21460 putative sugar uptake ABC transporter ATP-binding protein YP_001313134.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21459 putative sugar uptake ABC transporter permease protein YP_001313135.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21458 putative sugar uptake ABC transporter permease protein YP_001313136.1 KEGG: sme:SMb21456 hypothetical protein YP_001313137.1 PFAM: protein of unknown function DUF763; KEGG: sme:SMb21455 hypothetical protein YP_001313138.1 KEGG: sme:SMb21454 hypothetical protein YP_001313140.1 KEGG: sme:SMb21452 hypothetical protein YP_001313142.1 KEGG: sme:SMb21450 hypothetical protein YP_001313143.1 KEGG: sme:SMb21449 probable glutathione S-transferase protein YP_001313144.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: sme:SMb21448 putative DNA polymerase related protein YP_001313145.1 TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMb21447 putative 1,4-alpha-glucan branching enzyme protein YP_001313146.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMb21446 probable glycosyl hydrolase protein YP_001313147.1 KEGG: sme:SMb21445 putative DNA topoisomerase I protein YP_001313148.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sme:SMb21444 osmotic sensory protein YP_001313149.1 KEGG: sme:SMb21443 hypothetical protein YP_001313150.1 KEGG: atc:AGR_C_2256 hypothetical protein YP_001313151.1 PFAM: CBS domain containing protein; KEGG: sme:SMb21441 putative inosine-5'-monophosphate dehydrogenase protein YP_001313153.1 KEGG: sme:SMb21440 hypothetical protein YP_001313154.1 PFAM: UbiE/COQ5 methyltransferase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb21433 putative methyl-transferase, S-adenosyl-L-methionine (SAM)-MTase protein YP_001313155.1 PFAM: periplasmic binding protein; KEGG: atc:AGR_L_2862 putative iron complex transport system substrate-binding protein YP_001313156.1 PFAM: transport system permease protein; KEGG: sme:SMb21430 putative iron ABC transporter permease protein YP_001313157.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21429 putative iron ABC transporter ATP-binding protein YP_001313158.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: sme:SMb21415 putative oxidoreductase, oxygen dependent, FAD-dependent protein YP_001313159.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: sme:SMb21414 putative amino acid decarboxylase, pyridoxal-dependent protein YP_001313160.1 PFAM: Calcium-binding EF-hand-containing protein; KEGG: sme:SMb21413 hypothetical protein YP_001313161.1 PFAM: protein of unknown function DUF488; KEGG: sme:SMb21412 hypothetical protein YP_001313162.1 KEGG: rle:pRL120245 hypothetical protein YP_001313163.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb21410 putative methyltransferase, S-Adenosyl-L-methionine (SAM)-MTase protein YP_001313164.1 KEGG: reu:Reut_B5200 putative uncharacterized protein conserved in bacteria putative lipoprotein YP_001313166.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: sme:SMb20475 hypothetical protein YP_001313167.1 KEGG: sme:SMb20474 hypothetical protein YP_001313168.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1782 putative LysR-family transcriptional regulator YP_001313169.1 PFAM: transmembrane pair domain protein; KEGG: sme:SMa1780 hypothetical protein YP_001313170.1 KEGG: sme:SMb20513 hypothetical protein YP_001313171.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMa1582 hypothetical protein YP_001313172.1 PFAM: protein of unknown function DUF1486; KEGG: sme:SMa1589 hypothetical protein YP_001313173.1 KEGG: sme:SMb21030 hypothetical protein YP_001313174.1 KEGG: rle:RL1066 putative transmembrane protein YP_001313175.1 KEGG: rle:RL1067 hypothetical protein YP_001313176.1 KEGG: rle:RL0486 hypothetical protein YP_001313177.1 PFAM: regulatory protein TetR; KEGG: sco:SCO4454 transcriptional regulator YP_001313178.1 PFAM: protein of unknown function DUF1486; KEGG: mlo:mll8193 hypothetical protein YP_001313179.1 KEGG: ret:RHE_PE00376 hypothetical protein YP_001313180.1 PFAM: TspO/MBR family protein; KEGG: sme:SMa1079 TspO tryptophan rich sensory protein homologue YP_001313181.1 PFAM: protein of unknown function DUF378; KEGG: sme:SMa1078 hypothetical protein YP_001313182.1 PFAM: beta-Ig-H3/fasciclin; KEGG: sme:SMa1077 Nex18 symbiotically induced conserved protein YP_001313183.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: ret:RHE_PE00372 hypothetical protein YP_001313184.1 KEGG: sme:SMc01547 hypothetical protein YP_001313185.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bja:bll6530 transcriptional regulatory protein YP_001313186.1 PFAM: major facilitator superfamily MFS_1; KEGG: rle:pRL110158 putative transcription regulatory protein YP_001313187.1 KEGG: rle:pRL110145 hypothetical protein YP_001313188.1 PFAM: Carboxymuconolactone decarboxylase; Cupin 2 conserved barrel domain protein; KEGG: bxe:Bxe_B1954 hypothetical protein YP_001313189.1 KEGG: tde:TDE0356 hypothetical protein YP_001313190.1 KEGG: sme:SMc01546 hypothetical protein YP_001313191.1 KEGG: rle:RL1210 hypothetical protein YP_001313192.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: rle:pRL110542 putative cold shock protein YP_001313193.1 KEGG: ret:RHE_CH00434 hypothetical protein YP_001313194.1 KEGG: atc:AGR_pAT_759 hypothetical protein YP_001313195.1 KEGG: sme:SMc00281 hypothetical signal peptide protein YP_001313196.1 PFAM: helix-turn-helix domain protein; KEGG: noc:Noc_2930 transcriptional regulator, XRE family YP_001313197.1 PFAM: HipA domain protein; KEGG: ppd:Ppro_0263 HipA domain protein YP_001313198.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20904 putative sugar uptake ABC transporter ATP-binding protein YP_001313199.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20903 putative sugar uptake ABC transporter permease protein YP_001313200.1 TIGRFAM: D-xylose ABC transporter, periplasmic substrate-binding protein; KEGG: sme:SMb20902 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313201.1 KEGG: sme:SMb20901 putative transcriptional regulator protein YP_001313202.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb20899 hypothetical myo-inositol dehydrogenase protein YP_001313203.1 KEGG: sme:SMb20898 hypothetical protein YP_001313204.1 KEGG: sme:SMb20897 hypothetical protein YP_001313205.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20896 probable transcriptional regulator, LysR family, possibly activator of the expression of ChvE protein YP_001313206.1 KEGG: sme:SMb20895 probable sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313207.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20894 probable sugar uptake ABC transporter ATP-binding protein YP_001313208.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20893 probable sugar uptake ABC transporter permease protein YP_001313209.1 PFAM: protein of unknown function DUF1238; KEGG: sme:SMb20892 hypothetical protein YP_001313210.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20891 putative dehydrogenase, possibly aldehyde dehydrogenase protein YP_001313211.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001313212.1 KEGG: sme:SMb20889 hypothetical glycine-rich protein YP_001313213.1 PFAM: transglutaminase domain protein; transglutaminase domain protein; KEGG: sme:SMb20888 hypothetical protein YP_001313214.1 PFAM: protein of unknown function DUF403; KEGG: sme:SMb20887 hypothetical protein YP_001313215.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: sme:SMb20886 hypothetical protein YP_001313216.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMb20885 hypothetical protein YP_001313217.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sme:SMb20880 putative ATP-dependent RNA helicase protein YP_001313218.1 KEGG: sme:SMb20879 hypothetical protein YP_001313219.1 PFAM: protein of unknown function DUF752; KEGG: sme:SMb20878 hypothetical protein YP_001313220.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20877 putative oxidoreductase, possibly D-amino acid oxidase protein YP_001313221.1 PFAM: protein of unknown function DUF1045; KEGG: sme:SMb20876 hypothetical protein YP_001313222.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMb20875 hypothetical protein YP_001313223.1 KEGG: sme:SMb20874 hypothetical protein YP_001313224.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001313225.1 TIGRFAM: Hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: sme:SMb20872 conserved hypothetical protein, transthyretin-like protein YP_001313226.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: sme:SMb20850 putative L-lactate dehydrogenase (cytochrome) protein YP_001313227.1 Catalyzes the deamination of guanine YP_001313228.1 PFAM: protein of unknown function DUF989; KEGG: sme:SMb20848 conserved hypothetical membrane protein, paralogue of Y21292 YP_001313229.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20847 putative transcriptional regulator, LysR family protein YP_001313230.1 KEGG: sme:SMb21676 hypothetical protein YP_001313231.1 TIGRFAM: Xanthine dehydrogenase molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMb20846 probable xanthine dehydrogenase protein YP_001313232.1 TIGRFAM: Xanthine dehydrogenase small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: sme:SMb21011 probable xanthine dehydrogenase protein YP_001313233.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb21010 D-beta-hydroxybutyrate dehydrogenase protein YP_001313234.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: sme:SMb21009 probable glycerol kinase, similar to sugar kinases protein YP_001313235.1 PFAM: regulatory protein ArsR; KEGG: sme:SMb21008 putative transcriptional regulator, ArsR family protein YP_001313236.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMb21007 hypothetical protein YP_001313237.1 KEGG: mes:Meso_0629 hypothetical protein YP_001313238.1 PFAM: Domain of unknown function DUF1801; KEGG: sme:SMb21005 hypothetical protein YP_001313239.1 PFAM: Domain of unknown function DUF1801; KEGG: rle:RL2762 hypothetical protein YP_001313240.1 PFAM: luciferase family protein; KEGG: sme:SMb21003 putative oxidoreductase protein YP_001313241.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_001313242.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: sme:SMb21000 putative transport protein YP_001313243.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001313244.1 KEGG: sme:SMb20998 hypothetical protein YP_001313245.1 PFAM: NnrUfamily protein; KEGG: sme:SMb20997 putative membrane protein, similar to periplasmic nitrate reductase NnuR YP_001313246.1 KEGG: sme:SMb20996 hypothetical protein YP_001313247.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001313248.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: sme:SMb20994 hypothetical protein YP_001313249.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMb20993 putative FMNH2-dependent monooxygenase protein YP_001313250.1 similar to Y20991; KEGG: sme:SMb20992 conserved hypothetical protein, similar to Y20991 YP_001313251.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20991 conserved hypothetical protein, similar to Y20992, slightly similar to monooxygenase YP_001313252.1 PFAM: protein of unknown function DUF107; KEGG: sme:SMb20990 probable membrane protein necessary for nodulation competitiveness YP_001313253.1 PFAM: band 7 protein; KEGG: sme:SMb20989 putative stomatin-like protein YP_001313254.1 PFAM: NUDIX hydrolase; KEGG: sme:SMb20988 hypothetical protein YP_001313255.1 TIGRFAM: siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMb20987 putative siroheme synthetase protein YP_001313256.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sme:SMb20986 putative nitrate reductase, large subunit protein YP_001313257.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMb20985 putative nitrite reductase [NAD(P)H], small subunit protein YP_001313258.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sme:SMb20984 putative nitrite reductase [NAD(P)H], large subunit protein YP_001313260.1 KEGG: sme:SMb21114 putative nitrate transport protein YP_001313261.1 PFAM: response regulator receiver; ANTAR domain protein; KEGG: rle:RL1994 putative two component assimilatory nitrate reductase regulator response regulatory protein YP_001313262.1 PFAM: TfuA domain protein core; KEGG: sme:SMb21116 putative protein, similar to gene related to biosynthesis of peptide antibiotic trifolitoxin YP_001313263.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMb21117 putative transcriptional regulator protein YP_001313264.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: sme:SMb21119 putative gluconokinase protein YP_001313265.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMb21121 putative isovaleryl-CoA dehydrogenase protein YP_001313266.1 PFAM: carboxyl transferase; KEGG: sme:SMb21122 putative methylcrotonoyl-CoA carboxylase non-biotinylated subunit protein YP_001313267.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMb21123 hypothetical membrane-anchored protein, similar to putative translation initiation inhibitor YP_001313268.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: sme:SMb21124 putative methylcrotonoyl-CoA carboxylase biotinylated subunit protein YP_001313269.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_001313270.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001313271.1 KEGG: sme:SMb21127 hypothetical protein YP_001313272.1 PFAM: RES domain protein; KEGG: sme:SMb21128 conserved hypothetical membrane-anchored protein YP_001313273.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMb21129 putative oxidoreductase protein YP_001313274.1 TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21130 putative sulfate uptake ABC transporter ATP-binding protein YP_001313275.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21131 putative sulfate uptake ABC transporter permease protein YP_001313276.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21132 putative sulfate uptake ABC transporter permease protein YP_001313277.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21133 putative sulfate uptake ABC transporter periplasmic solute-binding protein precursor, similar to Y11244 YP_001313278.1 PFAM: alanine racemase domain protein; KEGG: sme:SMb21134 putative amino acid processing enzyme, similar to low specificity D-threonine aldolase protein YP_001313279.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMb21135 putative amino acid uptake ABC transporter periplasmic solute-binding protein precursor YP_001313280.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21136 putative amino acid uptake ABC transporter permease protein YP_001313281.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21137 putative amino acid uptake ABC transporter permease protein YP_001313282.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21138 putative amino acid uptake ABC transporter ATP-binding protein YP_001313283.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMb21139 putative protein, similar to translation initiation inhibitors YP_001313284.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMb21140 putative transcriptional regulator protein YP_001313285.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21216 putative sugar uptake ABC transporter ATP-binding protein YP_001313286.1 PFAM: PfkB domain protein; KEGG: sme:SMb21217 putative sugar kinase protein YP_001313287.1 PFAM: sugar isomerase (SIS); KEGG: sme:SMb21218 putative sugar-processing enzyme, possibly aminotransferase protein YP_001313288.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21219 putative sugar uptake ABC transporter permease protein YP_001313289.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21220 putative sugar uptake ABC transporter permease protein YP_001313290.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21221 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313291.1 PFAM: ROK family protein; KEGG: sme:SMb21222 putative transcriptional regulator protein YP_001313292.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001313293.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_001313294.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: sme:SMb21225 putative inositol monophosphatase, possibly involved in PAPS metabolism protein YP_001313295.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sme:SMb21226 putative histidinol phosphatase YP_001313296.1 undetermined role; similar to CarB protein but much smaller YP_001313297.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb21228 putative nucleotide sugar epimerase dehydratase protein YP_001313298.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMb21229 putative calcium-binding exported protein YP_001313299.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21230 putative glycosyltransferase protein YP_001313300.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21231 putative glycosyltransferase protein YP_001313301.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: sme:SMb21232 putative nucleotide sugar epimerase dehydratase protein YP_001313302.1 PFAM: formyl transferase domain protein; KEGG: sme:SMb21235 putative formyltransferase, similar to methionyl-tRNA(fMet) N-formyltransferase protein YP_001313303.1 KEGG: sme:SMb21236 putative ATPGTP-binding protein YP_001313304.1 C-terminal domain similar to sulfotransferase protein; KEGG: sme:SMb21237 putative enzyme, C-terminal domain similar to sulfotransferase protein YP_001313305.1 KEGG: sme:SMb21239 putative pectate lysase, possibly truncated due to chromosomal point mutation or sequencing artefact protein YP_001313306.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: sme:SMb21240 putative MPA1 family protein YP_001313307.1 KEGG: sme:SMb21241 hypothetical protein YP_001313308.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21242 putative glycosyltransferase protein YP_001313309.1 PFAM: sulfotransferase; KEGG: sme:SMb21243 putative sulfotransferase protein YP_001313310.1 PFAM: polysaccharide biosynthesis protein; KEGG: sme:SMb21244 putative membrane protein, similar to putative polysaccharide transporter YP_001313311.1 PFAM: polysaccharide export protein; KEGG: sme:SMb21245 putative OMA family outer membrane protein precursor, similar to ExoF YP_001313312.1 PFAM: sugar transferase; KEGG: sme:SMb21246 putative glycosyltransferase, possibly periplasmic protein YP_001313313.1 PFAM: LmbE family protein; KEGG: sme:SMb21247 conserved hypothetical protein, possibly membrane-associated YP_001313314.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMb21248 putative aminotransferase protein YP_001313315.1 PFAM: sulfotransferase; KEGG: sme:SMb21249 putative sulfotransferase protein YP_001313316.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21250 putative glycosyltransferase protein YP_001313317.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMb21251 conserved hypothetical membrane protein, similar to Y1058 YP_001313318.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21252 putative glycosyltransferase protein YP_001313319.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMb21253 hypothetical protein YP_001313320.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMb21254 hypothetical protein YP_001313321.1 KEGG: sme:SMb21255 hypothetical protein YP_001313322.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sme:SMb21256 putative nucleotide sugar oxidase protein YP_001313323.1 KEGG: rle:pRL110055 putative adenylate cyclase YP_001313324.1 KEGG: sme:SMb21259 hypothetical exported protein precursor YP_001313325.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb21260 putative mureinpeptideoligopeptide ABC transporter ATP-binding protein YP_001313326.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb21261 putative mureinpeptideoligopeptide ABC transporter periplasmic solute-binding protein precursor YP_001313327.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21262 putative mureinpeptideoligopeptide ABC transporter permease protein YP_001313328.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21263 putative mureinpeptideoligopeptide ABC transporter permease protein YP_001313329.1 KEGG: sme:SMb21264 putative membrane-anchored protein, slightly similar to UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase YP_001313330.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21265 putative glycosyltransferase protein YP_001313331.1 PFAM: Glycosyltransferase 28 domain; KEGG: sme:SMb21266 putative protein, slightly similar to UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase YP_001313332.1 KEGG: mlo:mll3253 hypothetical protein YP_001313333.1 PFAM: ABC transporter transmembrane region; ABC transporter related; KEGG: sme:SMb21269 putative ATP-binding component of an ABC transporter with an unusual central domain protein YP_001313334.1 PFAM: cyclic nucleotide-binding; KEGG: sme:SMb21270 putative transcriptional regulator protein YP_001313335.1 TIGRFAM: methyltransferase FkbM family; KEGG: sme:SMb21271 hypothetical nucleotide-binding protein YP_001313336.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb21272 putative LacI family transcritional regulator protein YP_001313337.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21273 putative spermidineputrescine ABC transporter periplasmic solute-binding protein precursor YP_001313338.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21274 putative spermidineputrescine ABC transporter permeasee protein YP_001313339.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21275 putative spermidineputrescine ABC transporter permease protein YP_001313340.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21276 putative spermidineputrescine ABC transporter ATP-binding protein YP_001313341.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: sme:SMb21277 putative inosine-uridine preferring nucleoside hydrolase protein YP_001313342.1 PFAM: amidohydrolase; KEGG: sme:SMb21278 probable adenine deaminase protein YP_001313344.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sme:SMb21279 putative amidohydrolase, similar to hippurate hydrolase protein YP_001313345.1 Involved in nucleotide synthesis and salvage YP_001313346.1 PFAM: protein of unknown function DUF411; KEGG: ret:RHE_PE00238 hypothetical protein YP_001313347.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sme:SMb21281 putative integral membrane transporter protein, xanthineuracil permeases family YP_001313348.1 KEGG: rru:Rru_A1249 kinase-like YP_001313349.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMb21284 putative enzyme, similar to uricase protein YP_001313350.1 TIGRFAM: Hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: sme:SMb21285 conserved hypothetical protein, transthyretin-like protein YP_001313351.1 TIGRFAM: Xanthine dehydrogenase small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: sme:SMb21286 probable xanthine dehydrogenase protein YP_001313352.1 TIGRFAM: Xanthine dehydrogenase molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMb21287 putative xanthine dehydrogenase protein YP_001313353.1 TIGRFAM: Xanthine dehydrogenase accessory protein XdhC; PFAM: protein of unknown function DUF182; KEGG: sme:SMb21288 probable xanthine dehydrogenase protein YP_001313354.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb21291 putative transcriptional regulator, LysR family protein YP_001313355.1 PFAM: protein of unknown function DUF989; KEGG: sme:SMb21292 conserved hypothetical membrane protein, paralogue of Y20848 YP_001313356.1 Catalyzes the deamination of guanine YP_001313357.1 PFAM: heat shock protein Hsp20; KEGG: sme:SMb21295 putative small heat shock protein, HSP20 family YP_001313358.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21296 hypothetical protein YP_001313359.1 TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: sme:SMb21297 probable bifunctional penicillin-binding protein YP_001313360.1 PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: sme:SMb21299 putative transcriptional regulator, DeoR family protein YP_001313361.1 TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sme:SMb21300 putative deoxyribose-phosphate aldolase protein YP_001313362.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb21301 putatively membrane-anchored aldehyde dehydrogenase protein YP_001313363.1 PFAM: RbsD or FucU transport; KEGG: sme:SMb21302 similar to protein from fucose degradation operon YP_001313364.1 PFAM: OsmC family protein; KEGG: sme:SMb21303 hypothetical membrane-anchored protein YP_001313365.1 PFAM: amidinotransferase; KEGG: sme:SMb21304 putative NG,NG-dimethylarginine dimethylaminohydrolase (dimethylargininase) protein YP_001313366.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_001313367.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMb21144 putative choline uptake ABC transporter periplasmic solute-binding protein precursor YP_001313368.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21145 putative choline uptake ABC transporter permease protein YP_001313369.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21146 putative choline uptake ABC transporter ATP-binding protein YP_001313370.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21147 putative choline uptake ABC transporter permease protein YP_001313371.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb21148 putative oxidoreductase protein YP_001313372.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21149 putative sugar uptake ABC transporter permease protein YP_001313373.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21150 putative sugar uptake ABC transporter permease protein YP_001313374.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21151 putative periplasmic solute-binding protein of a sugar uptake ABC transporter system YP_001313375.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21152 putative sugar uptake ABC transporter ATP-binding protein YP_001313376.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMb21153 putative acetyltransferase protein YP_001313377.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMb21154 hypothetical protein, bleomycin resistance protein family YP_001313378.1 PFAM: uncharacterised conserved protein UCP012702; MlrC domain protein; KEGG: sme:SMb21155 hypothetical protein YP_001313379.1 KEGG: sme:SMb21156 hypothetical protein YP_001313380.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMb21157 putative translation initiation inhibitor protein YP_001313381.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMb21158 putative transcriptional regulator, probably of sugar phosphate metabolism protein YP_001313382.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb21159 short chain dehydrogenase YP_001313383.1 PFAM: glycoside hydrolase family 20; KEGG: sme:SMb21160 putative glycosyl hydrolase, similar to beta-N-acetylhexosaminidases protein YP_001313384.1 PFAM: uncharacterised conserved protein UCP012702; MlrC domain protein; KEGG: sme:SMb21161 hypothetical protein YP_001313385.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb21162 putative integral membrane transporter protein YP_001313386.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001313387.1 PFAM: N-formylglutamate amidohydrolase; KEGG: sme:SMb21164 putative formiminoglutamase protein YP_001313388.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001313389.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001313390.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb21168 putative integral membrane transporter protein YP_001313391.1 PFAM: regulatory protein ArsR; KEGG: sme:SMb21169 putative transcriptional regulator, ArsR family protein YP_001313392.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: sme:SMb21170 putative guanylate kinase, also similar to E. coli PhnN protein YP_001313393.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMb21171 putative enzyme protein YP_001313394.1 PFAM: protein of unknown function DUF1045; KEGG: rle:RL0165 hypothetical protein YP_001313395.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21174 phosphate uptake ABC transporter permease protein YP_001313396.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21175 phosphate uptake ABC transporter permease protein YP_001313397.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: sme:SMb21176 phosphate uptake ABC transporter periplasmic solute-binding protein precursor YP_001313398.1 TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21177 phosphate uptake ABC transporter ATP-binding protein YP_001313399.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb21179 putative FAD-dependent glycerol-3-phosphate dehydrogenase protein YP_001313400.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb21180 putative transcriptional regulator, LysR family protein YP_001313401.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMb21181 putative glutaryl-CoA dehydrogenase protein YP_001313402.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sme:SMb21182 putative conserved membrane-anchored protein YP_001313403.1 molecular chaperone YP_001313404.1 catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs YP_001313405.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001313406.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sme:SMb21185 putative succinate-semialdehyde dehydrogenase (NAD(P)+) protein YP_001313407.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001313408.1 PFAM: regulatory protein MerR; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: sme:SMb21187 putative protein, similar to transcriptional regulators MerR and LacI family YP_001313409.1 PFAM: acyltransferase 3; KEGG: sme:SMb21188 putative acyltransferase, possibly surface-saccharide specific acetyltransferase protein YP_001313410.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb21189 putative glycosyltransferase protein YP_001313411.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb21190 putative glycosyltransferase protein YP_001313412.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21191 putative surface saccharide exporting ABC transporter protein, consisting of ATP-binding and membrane-spanning domains YP_001313413.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001313414.1 KEGG: sme:SMb21195 hypothetical protein YP_001313415.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb21196 putative oligopeptide uptake ABC transporter periplasmic solute-binding protein precursor YP_001313416.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21197 putative oligopeptide uptake ABC transporter permease protein YP_001313417.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21198 putative oligopeptide uptake ABC transporter permease protein YP_001313418.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb21199 putative oligopeptide uptake ABC transporter ATP-binding protein, consisting of 2 fused ATP-binding domains YP_001313419.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sme:SMb21200 putative two-component response regulator protein YP_001313420.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMb21201 putative two-component sensor histidine kinase protein YP_001313421.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMb21202 hypothetical protein YP_001313422.1 PFAM: phospholipase/Carboxylesterase; KEGG: sme:SMb21203 putative esteraselipase/thioesterase protein YP_001313423.1 TIGRFAM: prevent-host-death family protein; KEGG: tbd:Tbd_2423 prevent-host-death protein YP_001313424.1 KEGG: hha:Hhal_0789 PilT protein domain protein YP_001313425.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb21204 putative ABC transporter permease protein YP_001313426.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb21205 putative ABC transporter permease protein YP_001313427.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21206 putative ABC transporter ATP-binding protein, consisting of 2 fused ATP-binding domains YP_001313428.1 PFAM: secretion protein HlyD family protein; KEGG: sme:SMb21207 putative protein secretion protein, HlyD family YP_001313429.1 PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: sme:SMb21208 putative transcriptional regulator, TetR family protein YP_001313430.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01989 hypothetical protein YP_001313431.1 KEGG: sme:SMb21212 hypothetical protein YP_001313432.1 PFAM: metallophosphoesterase; KEGG: sme:SMb21213 putative serinethreonine protein phosphatase YP_001313433.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMb21214 putative 2-deoxyglucose-6-phosphate phosphatase protein YP_001313434.1 KEGG: sme:SMb21307 hypothetical protein YP_001313435.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21308 putative glycosyltransferase, forming alpha glycosyl linkages protein YP_001313436.1 KEGG: sme:SMb21309 hypothetical protein YP_001313437.1 KEGG: sme:SMb21310 putative membrane-anchored protein YP_001313438.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21311 putative glycosyltransferase, forming alpha-gylcosyl linkages protein YP_001313439.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb21312 putative methyltransferase protein YP_001313440.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb21313 putative bifunctional glycosyltransferase, forming alpha-glycosyl and beta-glycosyl linkages protein YP_001313441.1 KEGG: sme:SMb21314 putative secreted calcium-binding protein YP_001313442.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: sme:SMb21315 putative protein secretion protein, HlyD family membrane fusion protein, secretes ExpE1 YP_001313443.1 TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21316 putative ABC transporter protein, fused ATP-binding and membrane-spanning components, secretes ExpE1 YP_001313444.1 PFAM: regulatory protein MarR; KEGG: sme:SMb21317 transcriptional activator of exopolysaccharide II synthesis, MarR family protein YP_001313445.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21318 putative glycosyltransferase, forming alpha-glycosyl linkages protein YP_001313446.1 KEGG: sme:SMb21319 putative membrane-anchored protein YP_001313447.1 PFAM: glycosyl transferase family 2; glycosyl transferase group 1; KEGG: sme:SMb21320 putative bifunctional glycosyltransferase, forming beta-glycosyl and alpha-glycosyl linkages protein YP_001313448.1 PFAM: polysaccharide pyruvyl transferase; KEGG: sme:SMb21321 putative membrane-anchored protein YP_001313449.1 PFAM: polysaccharide pyruvyl transferase; KEGG: sme:SMb21322 putative membrane-anchored protein YP_001313450.1 KEGG: sme:SMb21323 putative protein, probably exported to periplasma YP_001313451.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sme:SMb21324 putative glucose-1-phosphate thymidyltransferase protein YP_001313452.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; KEGG: sme:SMb21325 putative dTDP-4-dehydrorhamnose 3,5-epimerase protein YP_001313453.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb21326 putative dTDP-D-glucose 4,6-dehydratase protein YP_001313454.1 PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb21327 putative dTDP-4-dehydrorhamnose reductase protein YP_001313455.1 KEGG: sme:SMb21328 putative Sir2-like transcriptional silencer protein YP_001313456.1 KEGG: sme:SMb21329 hypothetical exported peptide protein YP_001313457.1 PFAM: CsbD family protein; KEGG: sme:SMb21330 hypothetical protein with amino acid permeases signature YP_001313458.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sme:SMb21332 hypothetical protein YP_001313459.1 KEGG: sme:SMb21333 hypothetical protein YP_001313460.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMb21334 hypothetical exported glutamine-rich protein YP_001313461.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMb21335 conserved putative membrane protein, possibly a permease YP_001313462.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMb21336 putative transcriptional regulator, AraC family protein YP_001313463.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sme:SMb21337 putative iron-sulfur-binding protein, probably subunit of an oxidoreductase like aldehyde oxidase or xanthine dehydrogenase YP_001313464.1 PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: sme:SMb21338 putative molybdopterin binding protein, probably subunit of an oxidoreductase like aldehyde oxidase or xanthine dehydrogenase YP_001313465.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: xcb:XC_3780 oxidoreductase YP_001313466.1 PFAM: Phytanoyl-CoA dioxygenase; KEGG: sme:SMb21341 hypothetical protein YP_001313467.1 PFAM: inner-membrane translocator; KEGG: sme:SMb21342 putative sugar uptake ABC transporter permease protein YP_001313468.1 PFAM: inner-membrane translocator; KEGG: sme:SMb21343 putative sugar uptake ABC transporter permease protein YP_001313469.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21344 putative sugar uptake ABC transporter ATP-binding protein YP_001313470.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21345 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313471.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21346 putative transcriptional regulator, LacI family protein YP_001313472.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMb21347 putative pectin degradation protein YP_001313473.1 TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb21348 putative 2-deoxy-D-gluconate 3-dehydrogenase protein YP_001313474.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001313475.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb21350 putative transcriptional regulator, GntR family protein YP_001313476.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb21351 putative C4-dicarboxylate large membrane transport protein YP_001313477.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb21352 putative C4-dicarboxylate small membrane transport protein YP_001313478.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb21353 putative periplasmic C4-dicarboxylate transport protein YP_001313479.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001313480.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb21355 putative oxidoreductase protein YP_001313481.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN; KEGG: sme:SMb21356 conserved hypothetical membrane protein YP_001313482.1 KEGG: sme:SMb21357 hypothetical membrane protein YP_001313483.1 KEGG: sme:SMb21361 hypothetical membrane-anchored protein YP_001313484.1 KEGG: sme:SMb21362 hypothetical membrane-anchored protein YP_001313485.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN; KEGG: sme:SMb21363 conserved hypothetical membrane protein YP_001313486.1 similar to L-sorbosone dehydrogenase protein; KEGG: sme:SMb21364 putative membrane-anchored oxidoreductase, similar to L-sorbosone dehydrogenase protein YP_001313487.1 KEGG: sme:SMb21365 hypothetical membrane protein YP_001313488.1 KEGG: sme:SMb21366 hypothetical membrane protein YP_001313489.1 KEGG: sme:SMb21367 putative cytochrome c class I protein, probably cytochrome c4 YP_001313490.1 TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: sme:SMb21368 putative cytochrome c oxidase chain II protein YP_001313491.1 PFAM: sodium/calcium exchanger membrane region; KEGG: sme:SMb21369 hypothetical protein YP_001313492.1 TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I; KEGG: sme:SMb21370 putative cytochrome c oxidase chain I protein YP_001313493.1 KEGG: sme:SMb21371 hypothetical membrane protein YP_001313494.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb21372 putative transcriptional regulator, LacI family protein YP_001313495.1 PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: sme:SMb21373 putative sugar kinase protein YP_001313496.1 PFAM: PfkB domain protein; KEGG: sme:SMb21374 putative sugar kinase, PfkB family protein YP_001313497.1 PFAM: inner-membrane translocator; KEGG: sme:SMb21375 putative sugar uptake ABC transporter permease protein YP_001313498.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21376 putative sugar uptake ABC transporter ATP-binding protein YP_001313499.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21377 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313500.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMb21378 hypothetical protein YP_001313501.1 PFAM: protein of unknown function DUF427; KEGG: sme:SMb21379 hypothetical protein YP_001313504.1 KEGG: sme:SMb21395 hypothetical protein YP_001313505.1 KEGG: sme:SMb20922 hypothetical protein YP_001313506.1 KEGG: sme:SMb20922 hypothetical protein YP_001313507.1 PFAM: BA14K family protein; KEGG: sme:SMa0639 hypothetical protein YP_001313508.1 KEGG: sme:SMb20921 hypothetical protein YP_001313509.1 KEGG: sme:SMb20920 hypothetical secreted protein YP_001313510.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_pAT_530 hypothetical protein YP_001313511.1 PFAM: IS66 Orf2 family protein; KEGG: rle:pRL70145 putative transposase related protein YP_001313512.1 PFAM: transposase IS66; KEGG: ret:RHE_CH03056 probable insertion sequence transposase protein YP_001313513.1 KEGG: sme:SMb20920 hypothetical secreted protein YP_001313514.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: jan:Jann_4239 lipopolysaccharide biosynthesis YP_001313515.1 KEGG: jan:Jann_4240 ATPases involved in chromosome partitioning-like YP_001313516.1 PFAM: glycosyl transferase family 2; KEGG: ace:Acel_1912 glycosyl transferase, family 2 YP_001313517.1 KEGG: syc:syc1984_c hypothetical protein YP_001313518.1 KEGG: nha:Nham_4600 feruloyl esterase YP_001313519.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: mmr:Mmar10_2515 glycosyl transferase, WecB/TagA/CpsF family YP_001313520.1 PFAM: glycosyl transferase family 2; KEGG: pen:PSEEN2450 glycosyl transferase, group 2 family protein YP_001313521.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; KEGG: ret:RHE_CH03244 mannose-1-phosphate guanylyltransferase (GDP) protein YP_001313522.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: rle:RL3674 putative phosphomannomutase YP_001313523.1 KEGG: aau:AAur_2156 hypothetical protein YP_001313525.1 KEGG: nar:Saro_3228 hypothetical protein YP_001313526.1 PFAM: sugar transferase; KEGG: pde:Pden_0842 undecaprenyl-phosphate galactose phosphotransferase YP_001313527.1 PFAM: regulatory protein LuxR; KEGG: rle:pRL90149 putative transcriptional regulator YP_001313528.1 PFAM: glycosyl transferase family 2; KEGG: aau:AAur_2155 putative glycosyl transferase / polysaccharide biosynthesis domain protein YP_001313529.1 PFAM: glycosyl transferase group 1; KEGG: lxx:Lxx04950 glycosyl transferase YP_001313530.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: rle:pRL90150 putative hexapeptide repeat acetyltransferase YP_001313531.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; homoserine dehydrogenase NAD-binding; KEGG: rle:pRL90151 putative GFO/IDH/MocA family oxidoreductase YP_001313532.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rle:pRL90152 putative pleiotropic regulator YP_001313533.1 KEGG: ret:RHE_CH01366 hypothetical protein YP_001313534.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ret:RHE_CH01367 probable UDP-glucose 4-epimerase protein YP_001313535.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rle:pRL90155 putative DegT/DnrJ/EryC1/StrS family aminotransferase YP_001313536.1 PFAM: polysaccharide biosynthesis protein; KEGG: ret:RHE_CH01369 hypothetical protein YP_001313537.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mlo:mlr7553 dTDP-6-deoxy-L-mannose-dehydrogenase YP_001313538.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mlo:mlr7552 dTDP-D-glucose-4,6-dehydratase YP_001313539.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; KEGG: sme:SMb21325 putative dTDP-4-dehydrorhamnose 3,5-epimerase protein YP_001313540.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: mlo:mlr7550 glucose-1-phosphate thymidylyltransferase YP_001313541.1 PFAM: polysaccharide export protein; KEGG: rle:pRL90158 putative exopolysaccharide production protein YP_001313542.1 PFAM: regulatory protein LuxR; KEGG: atc:AGR_L_3006 hypothetical protein YP_001313543.1 KEGG: bms:BRA0772 hypothetical protein YP_001313544.1 PFAM: cyclic nucleotide-binding; KEGG: sme:SMb21079 putative transcriptional regulator protein YP_001313545.1 KEGG: sme:SMc03284 hypothetical/unknown protein YP_001313546.1 PFAM: regulatory protein LuxR; KEGG: sme:SMb21080 putative response regulator protein YP_001313547.1 KEGG: sme:SMc00940 hypothetical protein YP_001313548.1 KEGG: sme:SMc02316 hypothetical protein YP_001313550.1 PFAM: response regulator receiver; KEGG: sme:SMa0293 response regulator YP_001313553.1 KEGG: sme:SMb21682 hypothetical protein YP_001313554.1 KEGG: sme:SMb20913 hypothetical protein YP_001313555.1 PFAM: ATP dependent DNA ligase; KEGG: sme:SMb20912 putative ATP-dependent DNA ligase protein YP_001313556.1 KEGG: sme:SMb20911 hypothetical protein YP_001313557.1 KEGG: sme:SMb20910 hypothetical protein YP_001313559.1 KEGG: sme:SMb21681 hypothetical protein YP_001313560.1 KEGG: sme:SMb21680 hypothetical protein YP_001313561.1 PFAM: protein of unknown function DUF1452; KEGG: sme:SMb20908 hypothetical protein YP_001313563.1 KEGG: psb:Psyr_2843 C-5 cytosine-specific DNA methylase YP_001313565.1 KEGG: sme:SMb20548 hypothetical protein YP_001313566.1 KEGG: sme:SMb20548 hypothetical protein YP_001313568.1 TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine-binding; KEGG: rpe:RPE_3305 acyl carrier protein YP_001313569.1 KEGG: sme:SMb21026 hypothetical exopeptide protein YP_001313570.1 KEGG: mlo:mll4695 hypothetical protein YP_001313572.1 KEGG: mlo:mlr8001 hypothetical protein YP_001313573.1 PFAM: Transglycosylase-associated protein; KEGG: sme:SMa1766 hypothetical protein YP_001313574.1 PFAM: protein of unknown function DUF937; KEGG: sme:SMa1765 hypothetical protein YP_001313575.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMb21525 putative transcriptional regulator protein YP_001313576.1 TIGRFAM: taurine ABC transporter, periplasmic binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein family 3; KEGG: sme:SMb21526 putative taurine uptake ABC transporter periplasmic solute-binding protein precursor YP_001313577.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21527 putative taurin uptake ABC transporter ATP-binding protein YP_001313578.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21528 putative taurine uptake ABC transporter permease protein YP_001313579.1 PFAM: protein of unknown function DUF1486; KEGG: sme:SMb21670 taurine dehydrogenase small subunit YP_001313580.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb21529 taurine dehydrogenase large subunit YP_001313581.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: reh:H16_A2746 transcriptional regulator, IclR-family YP_001313582.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: reh:H16_B1851 glucose-methanol-choline oxidoreductase YP_001313583.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pde:Pden_4279 major facilitator superfamily MFS_1 YP_001313584.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_001313585.1 PFAM: conserved hypothetical protein 698; KEGG: sme:SMb21531 hypothetical protein YP_001313586.1 TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: sme:SMb21532 putative phosphate acetyltransferase protein YP_001313587.1 PFAM: regulatory protein GntR HTH; regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: sme:SMb21533 putative transcriptional regulator, GntR family protein YP_001313588.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMb21534 putative dehydrogenase protein YP_001313589.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb21535 putative transcriptional regulator, LysR family protein YP_001313590.1 PFAM: Na+cotransporter; PhoU family protein; KEGG: sme:SMb21536 hypothetical protein YP_001313591.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_001313592.1 TIGRFAM: phosphonoacetate hydrolase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: sme:SMb21538 putative phosphonoacetate hydrolase protein YP_001313593.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb21539 putative aldehyde dehydrogenase protein YP_001313594.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21540 putative iron uptake ABC transporter periplasmic solute-binding protein precursor YP_001313595.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21541 putative iron ABC transporter ATP-binding protein YP_001313596.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21542 putative iron uptake ABC transporter permease protein YP_001313597.1 PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: sme:SMa0599 hypothetical protein YP_001313598.1 KEGG: sme:SMa0601 hypothetical protein YP_001313599.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: sme:SMa0610 hypothetical protein YP_001313600.1 KEGG: rle:RL2265 hypothetical protein YP_001313601.1 KEGG: sme:SMc00958 hypothetical/unknown protein YP_001313602.1 PFAM: Integrase catalytic region; KEGG: sme:SMa2047 TRm24 putative transposase YP_001313603.1 PFAM: Integrase catalytic region; KEGG: ret:RHE_PA00137 putative insertion sequence transposase protein YP_001313604.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMb21570 putative NADH-dependent oxidase protein YP_001313605.1 PFAM: regulatory protein TetR; KEGG: sme:SMb21571 putative transcriptional regulator TetR family protein YP_001313606.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMb21572 putative amino acid uptake ABC transporter periplasmic solute-binding protein precursor YP_001313607.1 PFAM: Peptidoglycan-binding domain 1 protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMb21573 hypothetical protein YP_001313608.1 PFAM: Glutathione S-transferase domain; KEGG: rle:RL1444 putative glutathione S-transferase I YP_001313609.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb21575 putative transport protein YP_001313610.1 PFAM: regulatory protein ArsR; KEGG: sme:SMb21576 putative regulatory protein, ArsR family YP_001313612.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: pde:Pden_5003 cupin 2, conserved barrel domain protein YP_001313613.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc03937 putative adenylate/guanylate cyclase protein YP_001313614.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sme:SMb21578 putative copper-transporting P-type ATPase protein YP_001313615.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sme:SMb21579 putative transcriptional regulator, merR family protein YP_001313616.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMb21581 putative glycosyltransferase YP_001313617.1 PFAM: Exopolysaccharide synthesis ExoD; KEGG: sme:SMb21582 putative ExoD-like membrane protein YP_001313618.1 KEGG: sme:SMb21583 hypothetical protein YP_001313619.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: sme:SMb21045 putative reverse transcriptasematurase protein YP_001313621.1 KEGG: sme:SMb21584 hypothetical protein YP_001313622.1 PFAM: protein of unknown function DUF1704; KEGG: sme:SMb21585 hypothetical protein YP_001313623.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001313624.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21587 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313625.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21588 putative sugar uptake ABC transporter ATP-binding protein YP_001313626.1 PFAM: inner-membrane translocator; KEGG: sme:SMb21589 putative sugar uptake ABC transporter permease protein YP_001313627.1 membrane component of a putative sugar ABC transporter system YP_001313628.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMb21591 putative transcriptional regulator, GntR family protein YP_001313629.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21592 putative sugar uptake ABC transporter ATP-binding protein YP_001313630.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21593 putative sugar uptake ABC transporter permease protein YP_001313631.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21594 putative sugar uptake ABC transporter permease protein YP_001313632.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21595 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313633.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMb21596 hypothetical protein YP_001313634.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMb21597 putative exported oxidoreductase protein YP_001313635.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMb21598 putative transcriptional regulator protein YP_001313636.1 KEGG: sme:SMb21599 hypothetical protein YP_001313637.1 PFAM: beta-lactamase; KEGG: sme:SMb21600 putative exported beta-lactamase protein YP_001313638.1 PFAM: CBS domain containing protein; peptidase M50; KEGG: sme:SMb20925 hypothetical protein YP_001313639.1 KEGG: sme:SMb20926 hypothetical protein YP_001313640.1 PFAM: protein of unknown function DUF305; KEGG: rme:Rmet_2287 protein of unknown function DUF305 YP_001313641.1 KEGG: sme:SMb20927 hypothetical protein YP_001313642.1 PFAM: peptidase S41; SMART: PDZ/DHR/GLGF domain protein; KEGG: sme:SMb20928 putative exported carboxyl-terminal protease protein YP_001313643.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20929 putative sugar uptake ABC transporter permease protein YP_001313644.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20930 putative sugar uptake ABC transporter ATP-binding protein YP_001313645.1 KEGG: sme:SMb20931 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313646.1 PFAM: glycoside hydrolase family 16; Hemolysin-type calcium-binding region; KEGG: sme:SMb20932 endo-1,3-1,4-beta-glycanase, C-terminal secretion signal protein YP_001313647.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: sme:SMb20933 putative two-component sensor histidine kinase protein YP_001313648.1 PFAM: response regulator receiver; KEGG: sme:SMb20934 putative two-component response regulator protein YP_001313649.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMb20935 putative transcriptional regulator protein YP_001313651.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; KEGG: sme:SMb20937 putative ABC transporter protein consisting of fused ATP-binding and permease components YP_001313652.1 PFAM: Radical SAM domain protein; KEGG: sme:SMb20938 hypothetical protein YP_001313653.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: sme:SMb20939 6-pyruvoyltetrahydropterin synthase YP_001313654.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: sme:SMb20940 hypothetical protein YP_001313655.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: rsp:RSP_2053 possible transporter, RarD family, DMT superfamily YP_001313656.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20941 msbA-like saccharide exporting ABC transporter protein, consisting of ATP-binding and permease domains YP_001313657.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMb20942 UDP glucose 4-epimerase protein YP_001313658.1 PFAM: acyltransferase 3; KEGG: sme:SMb20943 acetyltransferase protein YP_001313659.1 PFAM: O-antigen polymerase; KEGG: sme:SMb20944 putative polysaccharide polymerase, similar to Wzy protein YP_001313660.1 PFAM: polysaccharide export protein; KEGG: sme:SMb20945 hypothetical outer membrane protein, similar to Wza, OMA family YP_001313661.1 PFAM: sugar transferase; KEGG: sme:SMb20946 galactosyltransferase protein YP_001313662.1 KEGG: sme:SMb20947 posttranscriptional regulator, repressor protein YP_001313663.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20948 glucosyltransferase protein YP_001313664.1 PFAM: ExoV-like protein; KEGG: sme:SMb20949 putative pyruvyltransferase protein YP_001313665.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb21690 glucosyltransferase protein YP_001313666.1 PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: sme:SMb20950 putative transport protein, similar to Wzx YP_001313667.1 KEGG: sme:SMb20952 hypothetical protein YP_001313668.1 KEGG: sme:SMb20954 succinyltransferase protein YP_001313669.1 PFAM: glycoside hydrolase family 16; KEGG: sme:SMb20955 endo-beta-1,3-1,4-glycanase protein YP_001313670.1 KEGG: sme:SMb20956 putative glucosyltransferase protein YP_001313671.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20957 glucosyltransferase protein YP_001313672.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20958 glucosyltransferase protein YP_001313673.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMb20959 glucosyltransferase protein YP_001313674.1 PFAM: Nucleotidyl transferase; KEGG: sme:SMb20960 UDPglucose pyrophosphorylase protein YP_001313675.1 TIGRFAM: exopolysaccharide transport protein family; PFAM: lipopolysaccharide biosynthesis protein; KEGG: sme:SMb20961 protein tyrosine kinase, MPA1 family, involved in succinoglycan chain-length determination YP_001313676.1 TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: sme:SMb20962 probable phoshomethylpyrimidine kinase protein YP_001313677.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMb20964 putative anti-oxidant protein, AhpCTSA family YP_001313678.1 PFAM: beta-lactamase; KEGG: sme:SMb20965 putative exported enzyme, similar to 6-aminohexanoate-dimer hydrolase protein YP_001313679.1 PFAM: MaoC domain protein dehydratase; KEGG: sme:SMb20978 hypothetical protein YP_001313680.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMb20979 putative large C4-dicarboxylate uptake permease protein, DedA family protein YP_001313681.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMb20980 putative small C4-dicarboxylate uptake permease protein YP_001313682.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMb20981 putative C4-dicarboxylate transporter periplasmic solute-binding protein precursor YP_001313683.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ret:RHE_PE00430 probable mandelate racemase protein YP_001313684.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMb21112 putative bifunctional enzyme 2-hydroxyhepta-2,4-diene-1,7-dioatesomerase 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase protein YP_001313685.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: sme:SMb21111 putative oxidoreductase, red superfamily protein YP_001313686.1 PFAM: MaoC domain protein dehydratase; KEGG: sme:SMb21110 putative MaoC-like (monoamine oxidase-like) protein, similar to NodN YP_001313687.1 PFAM: oxidoreductase domain protein; KEGG: sme:SMb21109 putative oxidoreductase protein YP_001313688.1 PFAM: protein of unknown function DUF718; KEGG: sme:SMb21108 conserved hypothetical protein, similar to Y03002 YP_001313689.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMb21107 putative mandelate racemase or evolutionary related enzyme of the mandelate racemase muconate lactonizing enzyme family protein YP_001313690.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb21106 putative sugar uptake ABC transporter ATP-binding protein YP_001313691.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21105 putative sugar uptake ABC transporter permease protein YP_001313692.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21104 putative sugar uptake ABC transporter permease protein YP_001313693.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21103 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001313694.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMb21102 putative transcriptional regulator protein YP_001313695.1 PFAM: amidohydrolase 2; KEGG: sme:SMb21101 conserved hypothetical membrane-anchored protein YP_001313696.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMb21100 putative saccharide deacetylase, slightly similar to NodB protein YP_001313697.1 PFAM: MmgE/PrpD family protein; KEGG: bam:Bamb_6463 MmgE/PrpD family protein YP_001313698.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMb21097 putative amino acid uptake ABC transporter periplasmic solute-binding protein precursor YP_001313699.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21096 putative amino acid transporter ABC transporter ATP-binding protein YP_001313700.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21095 putative amino acid uptake ABC transporter permease protein YP_001313701.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001313702.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb21093 putative transcriptional regulator, LysR family protein YP_001313703.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMb21092 putative acetyltransferase protein YP_001313704.1 PFAM: glycoside hydrolase family 25; KEGG: sme:SMb21091 putative cell-wall lytic enzyme, similar to muramidase protein YP_001313705.1 KEGG: sme:SMb21090 conserved hypothetical membrane-anchored protein YP_001313706.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: mlo:mll7158 hypothetical protein YP_001313707.1 PFAM: Capsule polysaccharide biosynthesis protein; KEGG: sme:SMb20834 probable surface saccharide synthesis protein, possibly involved in chain-length determination YP_001313708.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb20833 putative cell surface polysaccharide export ABC-2 transporter permease protein, close relative of Y20822wzm2 YP_001313709.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20832 putative cell surface polysaccharide export ABC-2 transporter ATP-binding protein YP_001313710.1 KEGG: sme:SMb20831 putative polysaccharide export-assoiated protein YP_001313711.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: sme:SMc02268 putative capsule expression protein YP_001313712.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMc02252 probable UDP-glucose 4-epimerase protein YP_001313713.1 PFAM: Capsule polysaccharide biosynthesis protein; KEGG: sme:SMb20823 putative cell surface saccharide synthesis protein, possibly involved in chain-length determination, truncated N-terminus YP_001313714.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMb20829 putative secreted calcium-binding protein YP_001313716.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: cjj:CJJ81176_1436 putative glycosyl transferase YP_001313717.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb20822 putative cell surface polysaccharide export ABC-2 transporter permease protein, close relative to wzm1Y20833 YP_001313718.1 PFAM: Ketopantoate hydroxymethyltransferase; KEGG: sme:SMb20821 putative ATPGTP-binding hydroxymethyltransferase protein YP_001313719.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMb20820 putative ferredoxin reductase protein YP_001313720.1 TIGRFAM: Rieske [2Fe-2S] domain protein, MocE subfamily; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMb20819 putative ferredoxin of the Rieseke type protein YP_001313721.1 PFAM: fatty acid desaturase; KEGG: sme:SMb20818 putative hydrocarbon oxygenase protein YP_001313722.1 PFAM: regulatory protein LacI; KEGG: sme:SMb20817 putative transcriptional regulator, LacI family protein YP_001313723.1 PFAM: AsmA family protein; KEGG: sme:SMb20815 putative protein, similar to protein involved in assembly of outer membrane proteins YP_001313724.1 KEGG: sme:SMb20814 hypothetical protein YP_001313725.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20813 putative lipid A + LPS core exporting ABC transporter protein, consisting of ATP-binding and permease domains YP_001313726.1 KEGG: sme:SMb20812 conserved hypothetical protein, possibly membrane-anchored YP_001313727.1 KEGG: sme:SMb20811 hypothetical protein YP_001313728.1 PFAM: acyltransferase 3; KEGG: sme:SMb20810 putative membrane-located cell surface saccharide saccharide acetylase protein YP_001313729.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: sme:SMb20809 putative protein involved in assembly, operation or regulation of an export machinery for a cell surface saccharide YP_001313730.1 KEGG: sme:SMb20808 putative membrane-anchored protein YP_001313731.1 PFAM: glycosyl transferase family 39; KEGG: sme:SMb20807 hypothetical protein YP_001313732.1 KEGG: sme:SMb20806 hypothetical protein YP_001313733.1 KEGG: sme:SMb20805 putative glycosyltransferase protein YP_001313734.1 KEGG: sme:SMb20804 putative membrane-anchored protein YP_001313735.1 KEGG: sme:SMb20803 probable 3-deoxy-manno-octulosonate cytidylyltransferase (CMP KDO transferase) protein YP_001313736.1 PFAM: protein of unknown function DUF23; KEGG: sme:SMb20563 hypothetical protein YP_001313737.1 KEGG: sme:SMb20562 hypothetical protein YP_001313738.1 KEGG: sme:SMb20043 hypothetical protein YP_001313739.1 PFAM: Heavy metal transport/detoxification protein; KEGG: sme:SMb20560 hypothetical protein YP_001313740.1 KEGG: sme:SMa1033 hypothetical protein YP_001313741.1 KEGG: sme:SMa1036 hypothetical protein YP_001313742.1 KEGG: sme:SMa1037 hypothetical protein YP_001313743.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sme:SMa1038 putative copper-containing oxidase YP_001313744.1 PFAM: blue (type 1) copper domain protein; KEGG: sme:SMa1041 putative copper oxidase, possibly exported YP_001313745.1 KEGG: sme:SMa1043 hypothetical protein YP_001313746.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMb21229 putative calcium-binding exported protein YP_001313747.1 KEGG: sme:SMb21035 hypothetical protein YP_001313748.1 KEGG: sme:SMb21036 hypothetical protein YP_001313749.1 PFAM: helix-turn-helix domain protein; KEGG: pde:Pden_3368 transcriptional regulator, XRE family YP_001313750.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb21037 putative oligopeptidemurein peptide ABC transporter periplasmic solute-binding protein precursor YP_001313751.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21038 putative oligopeptidemurein peptide ABC transporter permease protein YP_001313752.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21039 putative oligopeptidemurein peptide ABC transporter permease protein YP_001313753.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb21040 putative oligopeptidemurein peptide ABC transporter ATP-binding protein YP_001313754.1 possibly related to processing of cell wall amino acids; KEGG: sme:SMb21041 conserved putative protein, possibly related to processing of cell wall amino acids YP_001313755.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001313756.1 PFAM: protein of unknown function DUF736; KEGG: nwi:Nwi_0840 protein of unknown function DUF736 YP_001313758.1 PFAM: protein of unknown function DUF736; KEGG: nwi:Nwi_0840 protein of unknown function DUF736 YP_001313759.1 KEGG: rle:pRL80113 hypothetical protein YP_001313760.1 PFAM: Integrase catalytic region; KEGG: sme:SMc03283 putative transposase for insertion sequence ISRM18 YP_001313762.1 PFAM: Conjugal transfer TraD family protein; KEGG: rle:pRL70084 putative conjugal transfer protein YP_001313763.1 PFAM: TraC family protein; KEGG: ret:RHE_PA00158 conjugal transfer protein C YP_001313764.1 KEGG: nha:Nham_4172 ISSpo6, transposase orf A YP_001313765.1 TIGRFAM: Arsenate resistance ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: sal:Sala_2537 NADPH-dependent FMN reductase YP_001313766.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sal:Sala_2405 arsenical-resistance protein YP_001313767.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: rpa:RPA2257 arsenate reductase pump modifier YP_001313768.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: rpc:RPC_0618 protein tyrosine phosphatase YP_001313769.1 SMART: regulatory protein ArsR; KEGG: mes:Meso_4198 transcriptional regulator, ArsR family YP_001313770.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: sme:SMa1326 hypothetical protein YP_001313771.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMa1327 putative hydrolase YP_001313772.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMc03108 hypothetical calcium-binding protein YP_001313773.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa1367 putative dehdyrogenase YP_001313774.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMa1368 hypothetical protein YP_001313775.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa1370 probable ABC transporter ATP-binding protein YP_001313776.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa1371 probable ABC transporter ATP-binding protein YP_001313777.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1374 probable ABC transporter permease YP_001313778.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1373 probable ABC transporter permease YP_001313779.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa1375 probable ABC transporter, periplasmic solute-binding protein YP_001313780.1 PFAM: Amidase; KEGG: sme:SMa1377 putative amidase YP_001313782.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa1379 putative ABC transporter, periplasmic solute-binding protein YP_001313783.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMa1381 hypothetical protein YP_001313784.1 PFAM: ferredoxin; KEGG: sco:SCO6290 hypothetical protein YP_001313785.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMa1386 putative oxidoreductase YP_001313786.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1387 putative LysR-type transcriptional regulator YP_001313787.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: mlo:mll7935 transcriptional regulator YP_001313788.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001313789.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa1434 probable ABC transporter, ATP-binding protein YP_001313790.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1435 probable ABC transporter permease YP_001313791.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1437 probable ABC transporter permease YP_001313792.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa1438 putative ABC transporter, periplasmic solute-binding protein YP_001313793.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001313794.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa1442 putative GntR-family transcription factor YP_001313795.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sme:SMa1447 putative transmembrane transport protein YP_001313796.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pol:Bpro_3677 enoyl-CoA hydratase/isomerase YP_001313797.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; KEGG: mpt:Mpe_B0541 methylmalonyl-CoA mutase YP_001313798.1 TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase; KEGG: mpt:Mpe_B0540 putative transport system kinase YP_001313799.1 PFAM: cobalamin B12-binding domain protein; KEGG: mpt:Mpe_B0538 methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) YP_001313800.1 PFAM: aminotransferase class-III; KEGG: atc:AGR_pAT_435 hypothetical protein YP_001313801.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: atc:AGR_pAT_436 hypothetical protein YP_001313802.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: atc:AGR_L_644 PcaR protein YP_001313803.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; KEGG: atc:AGR_L_1055GM 3-oxoacid CoA-transferase subunit A YP_001313804.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; KEGG: atc:AGR_L_642 3-oxoacid CoA-transferase subunit B YP_001313805.1 TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: sme:SMb20589 putative beta-ketoadipyl CoA thiolase protein YP_001313806.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: sme:SMa1450 robable acyl-CoA thiolase YP_001313807.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa1452 probable 3-hydroxyacyl-CoA dehydrogenase YP_001313808.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMa1454 putative transcription factor YP_001313809.1 PFAM: RES domain protein; KEGG: sme:SMa1455 hypothetical protein YP_001313810.1 KEGG: sme:SMa1456 hypothetical protein YP_001313811.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: sme:SMa1459 putative malate dehydrogenase YP_001313812.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMa1461 putative muconate cycloisomerase YP_001313813.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMa1462 putative ABC transport protein YP_001313814.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1465 putative ABC transporter permease YP_001313815.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa1466 probable ABC transporter ATP binding protein YP_001313816.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1467 probable inner-membrane permease YP_001313817.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMa1471 hypothetical protein YP_001313818.1 PFAM: peptidase M24; KEGG: sme:SMa1473 putative aminopeptidase YP_001313819.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMa1476 putative AraC-family transcription regulator YP_001313820.1 PFAM: trimethylamine methyltransferase; KEGG: sme:SMa1478 putative methyltransferase YP_001313821.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1480 probable LysR-type activator YP_001313822.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMa1483 putative dimethylglycine dehydrogenase YP_001313823.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: sme:SMa1548 hypothetical protein YP_001313824.1 PFAM: regulatory protein LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system YP_001313825.1 PFAM: MCP methyltransferase CheR-type; Tetratricopeptide TPR_2 repeat protein; KEGG: sme:SMa1552 putative methyltransferase - chemotaxis YP_001313826.1 PFAM: CheW domain protein; KEGG: sme:SMa1554 putative purine-binding chemotaxis protein CheW YP_001313827.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein YP_001313828.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis YP_001313829.1 PFAM: CheB methylesterase; KEGG: sme:SMa1561 probable CheB2 chemotaxis methylesterase YP_001313830.1 PFAM: type II secretion system protein; KEGG: sme:SMa1562 hypothetical protein YP_001313831.1 PFAM: type II secretion system protein; KEGG: sme:SMa1564 hypothetical protein YP_001313832.1 PFAM: type II secretion system protein E; KEGG: sme:SMa1568 probable CpaF2 pilus assembly protein YP_001313833.1 PFAM: Flp/Fap pilin component; KEGG: sme:SMa1570 probable PilA2 pilus assembly protein YP_001313834.1 PFAM: TadE family protein; KEGG: sme:SMa1572 hypothetical protein YP_001313835.1 PFAM: TadE family protein; KEGG: sme:SMa1573 probable CpaE2 pilus assembly protein YP_001313836.1 PFAM: SAF domain protein; KEGG: sme:SMa1576 probable CpaB2 pilus assembly protein YP_001313837.1 PFAM: peptidase A24A prepilin type IV; KEGG: sme:SMa1578 prepilin peptidase CpaA YP_001313838.1 KEGG: sme:SMa1579 hypothetical protein YP_001313839.1 KEGG: sme:SMa1580 hypothetical protein YP_001313840.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMa0166 hypothetical protein YP_001313841.1 KEGG: sme:SMa0164 hypothetical protein YP_001313842.1 PFAM: type II and III secretion system protein; transport-associated; KEGG: sme:SMa0163 probable PilQ pilus assembly protein YP_001313843.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0160 putative GntR-family transcription regulator YP_001313844.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMa0157 hypothetical protein YP_001313845.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMa0155 hypothetical protein YP_001313846.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMa0151 hypothetical protein YP_001313847.1 PFAM: Malonyl-CoA decarboxylase; KEGG: sme:SMa0151 hypothetical protein YP_001313848.1 catalyzes the formation of malonyl-CoA from malonate and CoA YP_001313849.1 activates RNA polymerase to cleave back-tracked RNA during elongational pausing YP_001313850.1 KEGG: sme:SMa0148 hypothetical protein YP_001313851.1 KEGG: sme:SMa0146 hypothetical protein YP_001313852.1 KEGG: sme:SMa0144 hypothetical protein YP_001313853.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMa0143 putative RpoE6 RNA polymerase sigma factor YP_001313854.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: sme:SMa0142 possible protease YP_001313855.1 KEGG: sme:SMa0117 hypothetical protein YP_001313856.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: sme:SMa0116 putative DnaJ/CbpA-type protein YP_001313857.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rle:RL2065 hypothetical protein YP_001313858.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMa0185 possible transmembrane-transport protein YP_001313859.1 KEGG: ret:RHE_CH01058 hypothetical protein YP_001313860.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: bja:bll3153 hypothetical protein YP_001313861.1 PFAM: transposase IS4 family protein; KEGG: nha:Nham_2758 transposase, IS4 YP_001313862.1 KEGG: sme:SMa0254 hypothetical protein YP_001313863.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE4 domain protein; KEGG: sme:SMa0137 putative kinase/esterase YP_001313864.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMa0136 hypothetical protein YP_001313865.1 KEGG: atc:AGR_pAT_414 hypothetical protein YP_001313866.1 KEGG: sme:SMa0134 hypothetical protein YP_001313867.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sme:SMb20069 putative amino acid carrier protein YP_001313869.1 KEGG: sme:SMa0132 hypothetical protein YP_001313870.1 PFAM: fatty acid desaturase; KEGG: sme:SMa0130 putative fatty acid desaturase YP_001313871.1 KEGG: sme:SMa0128 hypothetical protein YP_001313872.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMa0126 putative cold shock protein YP_001313873.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa0110 putative ABC transporter ATP-binding protein YP_001313874.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa0108 putative ABC transporter, ATP-binding protein YP_001313875.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0106 putative ABC transporter, permease YP_001313876.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0105 putative ABC transporter permease protein YP_001313877.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa0104 putative ABC transporter, periplasmic solute-binding protein YP_001313878.1 PFAM: Amidohydrolase 3; KEGG: sme:SMa0101 hypothetical protein YP_001313879.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0097 putative transcriptional regulator YP_001313880.1 PFAM: peptidase S58 DmpA; KEGG: sme:SMa0095 putative D-aminopeptidase YP_001313881.1 PFAM: aminotransferase class IV; KEGG: sme:SMa0093 putative D-alanine aminotransferase YP_001313882.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMa2111 hypothetical protein YP_001313883.1 PFAM: regulatory protein MerR; Cobyrinic acid ac-diamide synthase; KEGG: sme:SMa2395 RepA2 replication protein YP_001313884.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; RepB plasmid partition; KEGG: sme:SMa2393 RepB2 replication protein YP_001313885.1 PFAM: replication protein C; KEGG: sme:SMa2391 RepC2 replication protein YP_001313886.1 PFAM: protein of unknown function DUF1127 YP_001313887.1 PFAM: periplasmic nitrate reductase NapE; KEGG: sme:SMa1241 NapE component of periplasmic nitrate reductase YP_001313888.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sme:SMa1240 NapF Ferredoxin component of periplasmic nitrate reductase YP_001313889.1 PFAM: NapD family protein; KEGG: sme:SMa1239 NapD component of periplasmic nitrate reductase YP_001313890.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001313891.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: sme:SMa1233 NapB periplasmic nitrate reductase YP_001313892.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: sme:SMa1232 NapC membrane protein, e-donor to periplasmic nitrate reductase YP_001313893.1 KEGG: sme:SMa0661 hypothetical protein YP_001313894.1 transcriptional regulator that positively regulated fixLJ operon; upregulated transcription by FixJ; part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes YP_001313895.1 KEGG: sme:SMa0663 hypothetical protein YP_001313896.1 KEGG: sme:SMa0664 hypothetical protein YP_001313897.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMa0665 hypothetical protein YP_001313898.1 KEGG: sme:SMa0667 hypothetical protein YP_001313899.1 PFAM: secretion protein HlyD family protein; KEGG: sme:SMa0669 hypothetical protein YP_001313900.1 PFAM: protein of unknown function DUF344; KEGG: sme:SMa0670 probable regulatory protein YP_001313901.1 KEGG: sme:SMa0674 hypothetical protein YP_001313902.1 TIGRFAM: calcium/proton antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: sme:SMa0675 cation (Ca) exchange protein, possible YP_001313903.1 SMART: extracellular solute-binding protein family 3; KEGG: sme:SMa0677 glutamate/aspartate transport protein, putative YP_001313904.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001313905.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sme:SMa0680 amino acid (ornithine, lysine, arginine) decarboxylase, probable YP_001313906.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sme:SMa0682 decarboxylase, probable (lysine, ornithine, arginine) YP_001313907.1 PFAM: cation efflux protein; KEGG: sme:SMa0683 hypothetical protein YP_001313908.1 PFAM: amino acid permease-associated region; KEGG: sme:SMa0684 probable transport protein YP_001313909.1 KEGG: sme:SMa0687 hypothetical protein YP_001313910.1 KEGG: sme:SMa0689 hypothetical protein YP_001313911.1 KEGG: sme:SMa0690 hypothetical protein YP_001313912.1 catalyzes the degradation of arginine to citruline and ammonia YP_001313913.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_001313914.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001313915.1 KEGG: sme:SMa0699 hypothetical protein YP_001313917.1 KEGG: rle:RL1645 hypothetical protein YP_001313918.1 PFAM: glycosyl transferase family 2; type IV pilus assembly PilZ; KEGG: rle:RL1646 putative cellulose synthase catalytic subunit [UDP-forming] YP_001313919.1 PFAM: cellulose synthase subunit B; KEGG: rle:RL1647 putative cellulose synthase protein YP_001313920.1 PFAM: glycoside hydrolase family 8; KEGG: ret:RHE_CH01544 endoglucanase (glycoside hydrolase) protein YP_001313921.1 KEGG: rle:RL1649 hypothetical protein YP_001313922.1 KEGG: atu:Atu4891 IS 426 transposase YP_001313923.1 KEGG: sme:SMa0210 hypothetical protein YP_001313924.1 KEGG: sme:SMa1750 hypothetical protein YP_001313925.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMa0319 putative AraC-type regulator YP_001313926.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa0320 putative oxidoreductase YP_001313927.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMa0322 hypothetical protein YP_001313928.1 PFAM: protein of unknown function DUF1330; KEGG: sme:SMa0323 hypothetical protein YP_001313929.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sme:SMa0325 hypothetical protein YP_001313930.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa0326 putative short-chain dehydrogenase YP_001313931.1 PFAM: DoxX family protein; KEGG: pfl:PFL_2372 SURF4 domain protein YP_001313932.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001313933.1 PFAM: protein of unknown function DUF1486; KEGG: sme:SMa0337 hypothetical protein YP_001313934.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa0339 putative oxidoreductase protein YP_001313935.1 stationary phase protein that binds TrpR repressor YP_001313936.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: sme:SMa0349 hypothetical protein YP_001313937.1 PFAM: Pirin domain protein; KEGG: sme:SMa0352 hypothetical protein YP_001313938.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0353 putative LysR-type regulator YP_001313939.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc00814 hypothetical signal peptide protein YP_001313940.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mxa:MXAN_0707 transcriptional regulator, AraC family YP_001313941.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMa1677 hypothetical protein YP_001313943.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMa1676 hypothetical protein YP_001313944.1 PFAM: Citrate transporter; KEGG: mgm:Mmc1_1409 citrate transporter YP_001313945.1 PFAM: peptidase M20; peptidase M42 family protein; peptidase dimerisation domain protein; KEGG: bja:bll2699 hypothetical protein YP_001313946.1 PFAM: AbgT putative transporter; KEGG: cpe:CPE0072 hypothetical protein YP_001313947.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mlo:mlr6727 transcriptional regulator YP_001313948.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0222 putative GntR-family transcriptional regulator YP_001313949.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMa0220 putative aldehyde YP_001313950.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMa0218 putative ABC transporter, periplasmic solute-binding protein YP_001313951.1 PFAM: inner-membrane translocator; KEGG: sme:SMa0217 putative ABC transporter, permease YP_001313952.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa0216 putative ABC transporter, ATP-binding protein YP_001313953.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1660 putative acetyltransferase YP_001313954.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sme:SMa1711 probable ArgI2 arginase YP_001313955.1 KEGG: sme:SMa1445 hypothetical protein YP_001313956.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001313957.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: reh:H16_B1020 predicted extracellular nuclease YP_001313958.1 PFAM: putative esterase; phospholipase/Carboxylesterase; KEGG: sme:SMb20552 hypothetical protein YP_001313960.1 KEGG: sme:SMc01548 hypothetical protein YP_001313961.1 KEGG: sme:SMa0287 hypothetical protein YP_001313962.1 TIGRFAM: putative integral membrane protein TIGR02587; KEGG: sme:SMa0288 hypothetical protein YP_001313963.1 KEGG: sme:SMa0291 hypothetical protein YP_001313964.1 PFAM: protein of unknown function DUF159; KEGG: ret:RHE_PF00147 hypothetical protein YP_001313965.1 KEGG: sme:SMa0421 hypothetical protein YP_001313966.1 PFAM: Glutathione S-transferase domain; KEGG: pde:Pden_2579 glutathione S-transferase, N-terminal domain YP_001313967.1 KEGG: sme:SMa0259 hypothetical protein YP_001313968.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMa0260 GabD3 succinate-semialdehyde dehdyrogenase YP_001313969.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sme:SMa0263 putative alcohol YP_001313970.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: sme:SMa0265 putative malate dehydrogenase YP_001313971.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0267 putative GntR-family regulator YP_001313972.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa0270 probable ABC transporter, ATP-binding protein YP_001313973.1 PFAM: inner-membrane translocator; KEGG: sme:SMa0271 putative ABC transporter - permease YP_001313974.1 KEGG: sme:SMa0273 putative ABC transporter, periplasmic solute-binding protein YP_001313975.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: sme:SMa0275 hypothetical protein YP_001313976.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMa1358 hypothetical protein YP_001313977.1 KEGG: mag:amb3465 predicted protein tyrosine phosphatase YP_001313979.1 3'-5' exonuclease of DNA polymerase III YP_001313980.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMa0089 hypothetical protein YP_001313981.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: xcb:XC_4261 transcriptional regulator YP_001313982.1 KEGG: sme:SMa1769 hypothetical protein YP_001313983.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1720 putative LysR-family transcriptional regulator YP_001313984.1 PFAM: amidohydrolase; KEGG: sme:SMa1718 putative AdeC4 adenine deaminase YP_001313985.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMa1717 putative integral membrane transporter YP_001313986.1 TIGRFAM: adenine deaminase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMa1715 putative AdeC3 adenine deaminase YP_001313987.1 PFAM: Hemolysin-type calcium-binding region; peptidase domain protein; KEGG: sme:SMb21543 putative outer membrane secretion protein YP_001313988.1 KEGG: sme:SMb21544 hypothetical protein YP_001313989.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: pde:Pden_4515 3-demethylubiquinone-9 3-methyltransferase YP_001313990.1 PFAM: NmrA family protein; KEGG: sme:SMa1957 hypothetical protein YP_001313991.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1956 putative LysR-family transcriptional regulator YP_001313992.1 PFAM: protein of unknown function DUF344; KEGG: sme:SMa0172 hypothetical protein YP_001313993.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMa1927 hypothetical protein YP_001313994.1 PFAM: cation transporter; KEGG: sme:SMa1691 putative TrkH-like protein YP_001313995.1 KEGG: sme:SMa0031 hypothetical protein YP_001313996.1 PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; Peptidase M10 serralysin; SMART: peptidase metallopeptidase; KEGG: sme:SMa0034 possible protease YP_001313997.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMa1945 hypothetical protein YP_001313998.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1943 putative transcriptional regulator YP_001313999.1 stationary phase protein that binds TrpR repressor YP_001314000.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pde:Pden_4563 transcriptional regulator, LysR family YP_001314001.1 PFAM: Glutathione S-transferase domain; KEGG: reu:Reut_B3491 glutathione S-transferase, N-terminal:glutathione S-transferase, C-terminal YP_001314002.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: rme:Rmet_1798 hypothetical protein YP_001314003.1 PFAM: regulatory protein ArsR; KEGG: mlo:mll3772 transcriptional regulator YP_001314004.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa0187 putative oxidoreductase YP_001314007.1 KEGG: sme:SMa1919 hypothetical protein YP_001314008.1 KEGG: sme:SMa1918 hypothetical protein YP_001314009.1 KEGG: sme:SMa1635 hypothetical protein YP_001314011.1 KEGG: sme:SMa1910 hypothetical protein YP_001314014.1 KEGG: sme:SMa1907 hypothetical protein YP_001314015.1 KEGG: atc:AGR_C_2256 hypothetical protein YP_001314016.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: atc:AGR_L_3316 hypothetical protein YP_001314017.1 PFAM: oxidoreductase domain protein; aldo/keto reductase; Oxidoreductase domain; homoserine dehydrogenase NAD-binding; KEGG: ret:RHE_PB00146 probable oxidoreductase protein YP_001314018.1 KEGG: atu:Atu5057 hypothetical protein YP_001314019.1 PFAM: aminotransferase class V; KEGG: sme:SMa1495 putative serine-pyruvate transaminase YP_001314020.1 KEGG: bja:blr6214 putative cytochrome c protein YP_001314022.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sme:SMa0196 putative gluconolactonase precursor YP_001314023.1 PFAM: inner-membrane translocator; KEGG: rle:pRL120287 putative permease component of ABC transporter YP_001314024.1 PFAM: inner-membrane translocator; KEGG: rle:pRL120286 putative permease component of ABC transporter YP_001314025.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rle:pRL120285 putative ATP-binding component of ABC transporter YP_001314026.1 KEGG: sme:SMa0203 putative ABC transporter YP_001314027.1 PFAM: ATP-binding region ATPase domain protein; KEGG: ret:RHE_PF00480 probable two-component sensor histidine kinase protein YP_001314028.1 PFAM: response regulator receiver; SMART: regulatory protein LuxR; KEGG: ret:RHE_PF00479 probable two-component response regulator protein YP_001314029.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMa2301 putative response regulator YP_001314030.1 KEGG: rle:RL2742 hypothetical protein YP_001314031.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: rle:RL2741 putative transmembrane thioredoxin/DipZ protein YP_001314032.1 PFAM: regulatory protein TetR; KEGG: sme:SMa2387 hypothetical protein YP_001314033.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa2385 probable ABC transporter, ATP-binding protein YP_001314034.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMa2383 probable oxidoreductase YP_001314035.1 PFAM: regulatory protein TetR; KEGG: sme:SMa2381 hypothetical protein YP_001314036.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: sme:SMa2379 catalase/peroxidase YP_001314037.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMa2377 putative transmembrane transport protein YP_001314038.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001314039.1 PFAM: inner-membrane translocator; KEGG: sme:SMa2369 putative ABC transporter, permease YP_001314040.1 PFAM: inner-membrane translocator; KEGG: sme:SMa2367 putative ABC transporter, permease YP_001314041.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa2365 probable ABC transporter, ATP-binding protein YP_001314042.1 PFAM: Amidase; KEGG: sme:SMa2363 putative amidase YP_001314043.1 PFAM: basic membrane lipoprotein; KEGG: sme:SMa2361 hypothetical protein YP_001314044.1 PFAM: aminotransferase class-III; KEGG: sme:SMc02413 putative aminotransferase protein YP_001314045.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMc02412 hypothetical protein YP_001314046.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02360 putative branched chain amino acid transport system permease ABC transporter protein YP_001314047.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02359 putative high-affinity branched-chain amino acid transport permease ABC transporter protein YP_001314048.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02358 putative high-affinity branched-chain amino acid transport ATP-binding ABC transporter protein YP_001314049.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02357 putative high-affinity branched-chain amino acid transport ATP-binding ABC transporter protein YP_001314050.1 PFAM: Extracellular ligand-binding receptor; KEGG: sme:SMc02356 putative branched chain amino acid binding periplasmic ABC transporter protein YP_001314051.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMc02355 hypothetical protein YP_001314052.1 PFAM: N-formylglutamate amidohydrolase; KEGG: sme:SMc02354 hypothetical protein YP_001314053.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMc02353 hypothetical protein YP_001314054.1 PFAM: glutamine synthetase catalytic region; KEGG: sme:SMc02352 putative glutamine synthetase protein YP_001314055.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001314056.1 PFAM: sodium/hydrogen exchanger; KEGG: rru:Rru_A1350 sodium/hydrogen exchanger YP_001314057.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMa2357 putative adenylate cyclase YP_001314058.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001314059.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMa2353 probable oxidoreductase YP_001314060.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sme:SMa2349 probable oxidoreductase YP_001314061.1 KEGG: sme:SMa2335 hypothetical protein YP_001314062.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001314063.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001314064.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001314065.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: sme:SMa2327 probable sensor protein YP_001314066.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMa2325 probable transcriptional regulator YP_001314067.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMa2359 hypothetical protein YP_001314068.1 PFAM: CBS domain containing protein; HPP family protein?; KEGG: sme:SMc02600 CBS domain-containing membrane protein YP_001314069.1 KEGG: sme:SMc02602 hypothetical protein YP_001314070.1 KEGG: sme:SMb20545 hypothetical protein YP_001314071.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sme:SMa2295 probable penicillin-binding protein YP_001314072.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa2293 probable beta lactamase transcriptional activator YP_001314073.1 PFAM: protein of unknown function DUF1127; KEGG: ret:RHE_PE00401 hypothetical protein YP_001314074.1 KEGG: sme:SMc02277 hypothetical unknown protein YP_001314075.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: sme:SMc02594 hypothetical protein YP_001314076.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pol:Bpro_3233 transcriptional regulator, LysR family YP_001314077.1 PFAM: autoinducer synthesis protein; KEGG: ret:RHE_PA00179 autoinducer synthesis protein I YP_001314078.1 VirB11 family protein; ATPase YP_001314079.1 PFAM: Conjugal transfer protein TrbC; KEGG: ret:RHE_PA00177 conjugal transfer protein C YP_001314080.1 PFAM: Conjugal transfer TrbD family protein; KEGG: ret:RHE_PA00176 conjugal transfer protein D YP_001314081.1 type IV secretion system ATPase; VirB4 family YP_001314082.1 TIGRFAM: P-type conjugative transfer protein TrbJ; KEGG: ret:RHE_PA00174 conjugal transfer protein J YP_001314084.1 TIGRFAM: P-type conjugative transfer protein TrbL; PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: ret:RHE_PA00173 conjugal transfer protein L YP_001314085.1 PFAM: Conjugal transfer protein; KEGG: ret:RHE_PA00172 conjugal transfer protein F YP_001314086.1 TIGRFAM: P-type conjugative transfer protein TrbG; PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: ret:RHE_PA00171 conjugal transfer protein G YP_001314087.1 KEGG: ret:RHE_PA00170 conjugal transfer protein H YP_001314088.1 PFAM: conjugation TrbI family protein; KEGG: ret:RHE_PA00169 conjugal transfer protein I YP_001314089.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: ret:RHE_PA00167 conjugal transfer transcriptional regulator protein, LuxR family YP_001314090.1 KEGG: ret:RHE_PA00166 conjugal transfer transcriptional regulator (repressor) protein YP_001314091.1 PFAM: helix-turn-helix domain protein; KEGG: bja:bsr0055 probable transcriptional regulator YP_001314092.1 PFAM: TraB family protein; KEGG: ret:RHE_PA00161 conjugal transfer protein B YP_001314093.1 TIGRFAM: Peptidase S26C conjugative transfer signal peptidase TraF; KEGG: ret:RHE_PA00160 conjugal transfer protein F YP_001314094.1 conjugal transfer system TraA; oriT nicking enzyme YP_001314095.1 PFAM: TraC family protein; KEGG: ret:RHE_PA00158 conjugal transfer protein C YP_001314096.1 PFAM: Conjugal transfer TraD family protein; KEGG: rle:pRL70084 putative conjugal transfer protein YP_001314097.1 VirD4 family YP_001314098.1 KEGG: mxa:MXAN_0377 hypothetical protein YP_001314099.1 PFAM: WGR domain protein; KEGG: rle:pRL70021 hypothetical protein YP_001314100.1 PFAM: protein of unknown function DUF736; KEGG: rle:pRL80113 hypothetical protein YP_001314101.1 PFAM: helix-turn-helix domain protein; KEGG: hne:HNE_0784 DNA-binding protein YP_001314102.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: pde:Pden_2612 sulphate transporter YP_001314103.1 KEGG: pde:Pden_2611 putative transcriptional regulator, XRE family YP_001314104.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: sus:Acid_7643 phage integrase family protein YP_001314105.1 PFAM: phage integrase family protein; KEGG: rme:Rmet_1272 phage integrase YP_001314106.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: mlo:mll6042 integrase/recombinase YP_001314107.1 PFAM: domain of unknown function DUF1738; KEGG: nha:Nham_0574 antirestriction protein YP_001314109.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001314110.1 possibly related to processing of cell wall amino acids; KEGG: sme:SMb21041 conserved putative protein, possibly related to processing of cell wall amino acids YP_001314111.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMb21040 putative oligopeptidemurein peptide ABC transporter ATP-binding protein YP_001314112.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21039 putative oligopeptidemurein peptide ABC transporter permease protein YP_001314113.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21038 putative oligopeptidemurein peptide ABC transporter permease protein YP_001314114.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMb21037 putative oligopeptidemurein peptide ABC transporter periplasmic solute-binding protein precursor YP_001314115.1 PFAM: helix-turn-helix domain protein; KEGG: pde:Pden_3368 transcriptional regulator, XRE family YP_001314116.1 KEGG: sme:SMb21036 hypothetical protein YP_001314117.1 KEGG: bmb:BruAb1_0291 hypothetical protein YP_001314118.1 KEGG: rle:pRL120653 hypothetical protein YP_001314119.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: rle:RL0595 putative cold shock protein YP_001314121.1 KEGG: mlo:mlr9078 hypothetical protein YP_001314122.1 PFAM: RES domain protein; KEGG: sme:SMa2279 hypothetical protein YP_001314123.1 KEGG: sme:SMa2259 hypothetical protein YP_001314125.1 KEGG: rme:Rmet_2595 hypothetical protein YP_001314127.1 PFAM: phage integrase family protein; KEGG: sme:SMa2257 possible integrase-like protein YP_001314128.1 PFAM: PilT protein domain protein; KEGG: nha:Nham_4577 PilT protein-like YP_001314129.1 KEGG: mlo:msl5079 hypothetical protein YP_001314130.1 KEGG: azo:azo1600 conserved hypothetical protein YP_001314131.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tbd:Tbd_1491 adenine specific DNA-methyltransferase YP_001314132.1 PFAM: type III restriction protein res subunit; KEGG: tbd:Tbd_1492 type III restriction-modification enzyme helicase subunit YP_001314133.1 KEGG: sco:SCO3291 regulatory protein YP_001314134.1 KEGG: bba:Bd1459 hypothetical protein YP_001314135.1 PFAM: UvrD/REP helicase; KEGG: ade:Adeh_2512 UvrD/REP helicase YP_001314137.1 KEGG: mmr:Mmar10_1479 transcriptional regulator YP_001314138.1 KEGG: nar:Saro_0348 hypothetical protein YP_001314140.1 KEGG: nha:Nham_4172 ISSpo6, transposase orf A YP_001314141.1 KEGG: ade:Adeh_3543 hypothetical protein YP_001314143.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR_2 repeat protein; KEGG: sme:SMa0570 putative CyaF4 adenylate cyclase YP_001314144.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMa1727 putative hydrolase YP_001314145.1 PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: mlo:mll9026 transposase YP_001314147.1 KEGG: bja:bll1928 hypothetical protein YP_001314148.1 PFAM: Domain of unknown function DUF1814; KEGG: bja:bll1927 hypothetical protein YP_001314149.1 PFAM: PfkB domain protein; KEGG: bsu:BG13998 similar to opine catabolism protein YP_001314150.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rsp:RSP_3939 transcriptional regulator, LacI family YP_001314151.1 PFAM: extracellular solute-binding protein family 3; KEGG: fal:FRAAL5986 putative arginine transport protein (ABC superfamily, peri_bind) YP_001314152.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bxe:Bxe_C1161 ABC polar amino acid family transporter, inner membrane subunit YP_001314153.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nfa:nfa18910 putative ABC transporter ATP-binding protein YP_001314154.1 PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: mlo:mlr3204 ornithine cyclodeaminase YP_001314155.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: bsu:BG13997 similar to transcriptional regulator (GntR family) YP_001314156.1 PFAM: sugar isomerase (SIS); KEGG: bsu:BG14002 similar to opine catabolism protein YP_001314157.1 PFAM: FAD dependent oxidoreductase; KEGG: pde:Pden_1191 FAD dependent oxidoreductase YP_001314158.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: cac:CAC3499 predicted endonuclease YP_001314159.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pde:Pden_4951 NADH:flavin oxidoreductase/NADH oxidase YP_001314161.1 PFAM: FAD linked oxidase domain protein; KEGG: reh:H16_B1827 FAD/FMN-containing dehydrogenase YP_001314162.1 PFAM: extracellular solute-binding protein family 1; KEGG: reh:H16_B1828 ABC-type transporter, periplasmic component: POPT family YP_001314163.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: reh:H16_B1829 ABC-type transporter, ATPase component: POPT family YP_001314164.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: reh:H16_B1830 ABC-type transporter, duplicated permease domains YP_001314165.1 PFAM: dihydrodipicolinate synthetase; KEGG: bbr:BB1108 putative dihydrodipicolinate synthase YP_001314166.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: reh:H16_B1833 transcriptional regulator, IclR-family YP_001314167.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001314168.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: pde:Pden_4877 L-lactate dehydrogenase (cytochrome) YP_001314169.1 TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: sme:SMa0483 putative inositol monophosphatase YP_001314170.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: bja:bll3011 virulence-associated protein I YP_001314171.1 PFAM: plasmid maintenance system killer; KEGG: hne:HNE_2665 plasmid maintenance system killer protein YP_001314172.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase subunit FdhD; KEGG: sit:TM1040_3756 formate dehydrogenase family accessory protein FdhD YP_001314173.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001314174.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001314175.1 KEGG: mes:Meso_2452 hypothetical protein YP_001314176.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: mes:Meso_2451 formate dehydrogenase, gamma subunit YP_001314177.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mes:Meso_2450 4Fe-4S ferredoxin, iron-sulfur binding YP_001314178.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mes:Meso_2449 twin-arginine translocation pathway signal YP_001314179.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: mes:Meso_2448 twin-arginine translocation pathway signal YP_001314180.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: mes:Meso_2447 cytoplasmic chaperone TorD YP_001314181.1 KEGG: mes:Meso_2446 hypothetical protein YP_001314182.1 KEGG: mes:Meso_2445 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001314183.1 KEGG: mes:Meso_2444 hypothetical protein YP_001314184.1 KEGG: mes:Meso_2443 hypothetical protein YP_001314185.1 KEGG: mes:Meso_2442 hypothetical protein YP_001314186.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mes:Meso_2441 4Fe-4S ferredoxin, iron-sulfur binding YP_001314187.1 PFAM: WD-40 repeat protein; cytochrome c class I; KEGG: mes:Meso_2440 WD-40 repeat YP_001314188.1 KEGG: mes:Meso_2439 hypothetical protein YP_001314189.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: mes:Meso_2438 DNA binding domain, excisionase family YP_001314190.1 KEGG: mes:Meso_2437 binding-protein-dependent transport systems inner membrane component YP_001314191.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mes:Meso_2436 ABC transporter related YP_001314192.1 KEGG: mes:Meso_2435 extracellular solute-binding protein, family 1 YP_001314193.1 PFAM: molybdopterin binding domain; MoeA domain protein domain IV; KEGG: mes:Meso_2434 molybdopterin binding domain YP_001314194.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: mes:Meso_2433 molybdenum cofactor synthesis domain YP_001314195.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: bxe:Bxe_A1506 hypothetical protein YP_001314196.1 KEGG: sme:SMa1597 putative fimbrial chaperone protein YP_001314197.1 TIGRFAM: yecA family protein; KEGG: sme:SMc03284 hypothetical/unknown protein YP_001314198.1 PFAM: transposase IS66; KEGG: bms:BRA0556 IS66 family element, orf3, putative YP_001314199.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: sme:SMb21045 putative reverse transcriptasematurase protein YP_001314200.1 PFAM: transposase IS66; KEGG: sme:SMc03280 putative transposase number 3 for insertion sequence ISRM28 YP_001314201.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMc03279 putative transposase number 2 for insertion sequence ISRM28 YP_001314202.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03278 putative transposase number 1 for insertion sequence ISRM28 YP_001314203.1 PFAM: isochorismatase hydrolase; KEGG: rle:RL1850 putative isochorismatase family protein YP_001314204.1 KEGG: ret:RHE_PF00543 hypothetical protein YP_001314205.1 PFAM: alpha/beta hydrolase fold; Epoxide hydrolase domain protein; KEGG: mlo:mlr6682 epoxide hydrolase YP_001314206.1 PFAM: response regulator receiver; KEGG: pfo:Pfl_2250 response regulator receiver domain protein (CheY) YP_001314207.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: pfo:Pfl_2251 PAS/PAC sensor signal transduction histidine kinase YP_001314208.1 PFAM: response regulator receiver; KEGG: pfo:Pfl_2250 response regulator receiver domain protein (CheY) YP_001314209.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: pfo:Pfl_2251 PAS/PAC sensor signal transduction histidine kinase YP_001314210.1 KEGG: aba:Acid345_0842 hypothetical protein YP_001314211.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20211 putative transcriptional regulator protein YP_001314212.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ret:RHE_PF00545 hypothetical protein YP_001314213.1 PFAM: alpha/beta hydrolase fold; Epoxide hydrolase domain protein; KEGG: bch:Bcen2424_3503 epoxide hydrolase domain protein YP_001314214.1 PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; KEGG: sme:SMb20214 putative oxidoreductase protein YP_001314215.1 catalyzes the formation of pyruvate from D-cysteine YP_001314216.1 PFAM: NADPH-dependent FMN reductase; KEGG: pde:Pden_0330 NADPH-dependent FMN reductase YP_001314218.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ret:RHE_PF00542 probable enoyl-CoA hydratase protein YP_001314219.1 PFAM: Endoribonuclease L-PSP; KEGG: ret:RHE_PF00541 hypothetical protein YP_001314220.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ret:RHE_PF00540 probable oxidoreductase protein YP_001314221.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: ret:RHE_PF00539 probable dioxygenase protein YP_001314222.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: pol:Bpro_1488 protein of unknown function DUF1228 YP_001314223.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: pfo:Pfl_5708 two component transcriptional regulator, LuxR family YP_001314225.1 PFAM: ThiJ/PfpI domain protein; KEGG: ret:RHE_PF00538 hypothetical protein YP_001314226.1 KEGG: rle:RL1855 hypothetical protein YP_001314228.1 PFAM: alpha/beta hydrolase fold; KEGG: ret:RHE_PF00536 probable epoxide hydrolase protein YP_001314229.1 PFAM: aldehyde dehydrogenase; KEGG: ret:RHE_PF00534 probable aldehyde dehydrogenase protein YP_001314231.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: pfo:Pfl_2251 PAS/PAC sensor signal transduction histidine kinase YP_001314232.1 KEGG: par:Psyc_1582 MFS Ni2+ efflux pump NreB YP_001314235.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: rle:RL3793 putative LacI family transcriptional regulator YP_001314236.1 PFAM: extracellular solute-binding protein family 5; KEGG: rle:RL3794 putative solute-binding component of ABC transporter YP_001314237.1 PFAM: protein of unknown function DUF187; KEGG: rle:RL3795 hypothetical protein YP_001314238.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL3796 putative transmembrane component of ABC transporter YP_001314239.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL3797 putative transmembrane component of ABC transporter YP_001314240.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: rle:RL3798 putative ATP-binding component of ABC transporter YP_001314241.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mes:Meso_4459 xylose isomerase-like TIM barrel YP_001314242.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rle:RL3800 putative oxidoreductase YP_001314243.1 PFAM: MOFRL domain protein; KEGG: ret:RHE_CH01794 hydroxypyruvate reductase protein YP_001314244.1 KEGG: atc:AGR_L_701 hypothetical protein YP_001314245.1 KEGG: ret:RHE_CH03919 hypothetical protein YP_001314246.1 PFAM: OsmC family protein; KEGG: ret:RHE_CH03920 putative stress-induced OsmC-like protein YP_001314247.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rme:Rmet_4523 short-chain dehydrogenase/reductase SDR YP_001314248.1 KEGG: ret:RHE_CH03921 hypothetical protein YP_001314249.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ret:RHE_CH03922 probable transcriptional regulator protein, LysR family YP_001314250.1 KEGG: rle:pRL110579 putative transmembrane protein YP_001314251.1 PFAM: alpha/beta hydrolase fold; OsmC family protein; KEGG: sme:SMa1898 putative redox protein YP_001314252.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001314253.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001314254.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1893 putative LysR-family transcriptional activator YP_001314255.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rle:RL2731 putative two-component sensor histidine kinase transcriptional regulatory protein YP_001314256.1 PFAM: KaiA binding; SMART: AAA ATPase; KEGG: rle:RL2732 putative protein kinase YP_001314257.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: rle:pRL120741 hypothetical protein YP_001314258.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mlo:mlr3587 ALPHA-GLUCOSIDES TRANSPORT ATP-BINDING PROTEIN AGLK YP_001314259.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mll3588 sugar transporter integral membrane protein (permease) YP_001314260.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mll3589 sugar transporter integral membrane protein (permease) YP_001314261.1 PFAM: extracellular solute-binding protein family 1; KEGG: mlo:mll3590 sugar transporter sugar binding protein YP_001314262.1 PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: mlo:mll3591 alpha-L-arabinofuranosidase YP_001314263.1 PFAM: regulatory protein ArsR; transcriptional regulator TrmB; KEGG: mlo:mll3592 hypothetical protein YP_001314265.1 KEGG: azo:azo2433 short-chain dehydrogenase family protein YP_001314266.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMa1869 putative deaminase YP_001314267.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMa1867 putative AsnC (lrp)-family transcriptional activator YP_001314268.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa1864 putative ABC transporter, ATP-binding protein YP_001314269.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1863 putative ABC transporter, permease protein YP_001314270.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1862 putative ABC transporter, permease protein YP_001314271.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa1860 putative ABC transporter, periplasmic solute-binding protein YP_001314272.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); KEGG: sme:SMa1857 hypothetical protein YP_001314273.1 PFAM: aminotransferase class-III; KEGG: sme:SMa1855 hypothetical protein YP_001314274.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1853 hypothetical protein YP_001314275.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMa1851 putative dehalogenase YP_001314276.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMa1850 putative oxidoreductase YP_001314277.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sme:SMa1848 GabD5 succinate semialdehyde dehdyrogenase YP_001314278.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001314279.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMa1844 putative aldehyde YP_001314280.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: sme:SMa1840 hypothetical protein YP_001314281.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMa1838 hypothetical protein YP_001314282.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001314283.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1835 hypothetical protein YP_001314284.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00807 putative transport transmembrane protein YP_001314285.1 PFAM: high-affinity nickel-transporter; KEGG: sme:SMa1644 hypothetical protein YP_001314286.1 PFAM: SNARE associated Golgi protein; KEGG: atc:AGR_L_3254 hypothetical protein YP_001314287.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMa1641 probable NreB protein YP_001314288.1 PFAM: protein of unknown function DUF156; KEGG: rle:RL1176 hypothetical protein YP_001314289.1 KEGG: sme:SMa1638 hypothetical protein YP_001314290.1 KEGG: maq:Maqu_3196 putative ORF1 (plasmid pTOM9) YP_001314291.1 KEGG: maq:Maqu_3197 putative (L31491) ORF2; putative (plasmid pTOM9) YP_001314292.1 KEGG: rle:RL1179 hypothetical protein YP_001314293.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa1654 putative GntR-family transcriptional regulator YP_001314294.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa1651 putative ABC transporter, periplasmic solute-binding protein YP_001314295.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1650 putative ABC transporter, permease protein YP_001314296.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1649 putative ABC transporter, permease protein YP_001314297.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa1647 putative ABC transporter, ATP-binding protein YP_001314298.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa1646 putative ABC transporter, ATP-binding protein YP_001314299.1 PFAM: Integrase catalytic region; KEGG: bja:bll1940 putative transposase YP_001314300.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: ret:RHE_PA00081 probable insertion sequence ATP-binding protein, IS21 family YP_001314301.1 KEGG: rle:pRL110217 hypothetical protein YP_001314303.1 KEGG: mlo:mlr2577 hypothetical protein YP_001314304.1 KEGG: sme:SMc01774 hypothetical protein YP_001314306.1 PFAM: response regulator receiver; KEGG: sme:SMa1688 putative two-component response regulator YP_001314307.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMa1686 putative two-component response regulator YP_001314308.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMa0939 probable sensor histidine kinase of two-component system YP_001314309.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: mlo:mll5470 hypothetical protein YP_001314310.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: rde:RD1_3749 hypothetical protein YP_001314312.1 KEGG: bsu:BG10456 tunicamycin resistance protein YP_001314313.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMa0175 hypothetical protein YP_001314314.1 KEGG: sme:SMa2101 probable nitrilotriacetate monooxygenase component A YP_001314315.1 KEGG: sme:SMa2099 hypothetical protein YP_001314316.1 PFAM: monooxygenase FAD-binding; KEGG: sme:SMa2097 hypothetical protein YP_001314317.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sme:SMa2095 hypothetical protein YP_001314318.1 KEGG: sme:SMa2093 hypothetical protein YP_001314319.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMa2091 hypothetical protein YP_001314320.1 KEGG: sme:SMa2087 hypothetical protein YP_001314321.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa2085 probable ABC transporter, permease protein YP_001314322.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa2083 probable ABC transporter, permease protein YP_001314323.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa2081 probable ABC transporter, ATP-binding protein YP_001314324.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMa2079 probable ABC transporter, ATP-binding protein YP_001314325.1 PFAM: aldo/keto reductase; KEGG: sme:SMa2077 probable oxidoreductase YP_001314326.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMa2075 probable extracellular solute-binding protein, family 5 YP_001314327.1 PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMa2073 hypothetical protein YP_001314328.1 PFAM: Ion transport 2 domain protein; KEGG: rme:Rmet_1713 ion transport 2 YP_001314329.1 PFAM: protein of unknown function UPF0118; KEGG: bxe:Bxe_A3174 hypothetical protein YP_001314330.1 KEGG: rle:RL2870 putative transmembrane protein YP_001314331.1 PFAM: secretion protein HlyD family protein; KEGG: rle:RL2871 putative transmembrane efflux pump YP_001314333.1 KEGG: ret:RHE_PE00297 putative plasmid stabilization protein YP_001314334.1 KEGG: ret:RHE_PE00296 putative plasmid stability protein YP_001314335.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein; KEGG: mlo:mll4364 hypothetical protein YP_001314336.1 KEGG: sme:SMa1702 hypothetical 21.7 KDA protein in syrb 5'region (ORF4) YP_001314337.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMa1698 SyrB regulatory protein YP_001314338.1 KEGG: sme:SMa1697 hypothetical protein YP_001314340.1 PFAM: helix-turn-helix domain protein; KEGG: sus:Acid_2062 putative transcriptional regulator, XRE family YP_001314341.1 PFAM: HipA domain protein; KEGG: neu:NE1310 possible HipA protein YP_001314342.1 KEGG: gbe:GbCGDNIH1_1624 hypothetical membrane spanning protein YP_001314343.1 PFAM: glycosyl transferase group 1; KEGG: sde:Sde_0148 glycoside hydrolase, family 10 YP_001314344.1 PFAM: UDP-galactopyranose mutase; KEGG: xcb:XC_3769 UDP-galactopyranose mutase YP_001314345.1 PFAM: oxidoreductase domain protein; glycosyl transferase group 1; Oxidoreductase domain; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mkm:Mkms_3977 alcohol dehydrogenase, zinc-binding domain protein YP_001314346.1 PFAM: glycosyl transferase group 1; KEGG: mfa:Mfla_1193 hypothetical protein YP_001314349.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; sterile alpha motif SAM protein; Sterile alpha motif homology 2; SMART: Tetratricopeptide domain protein; KEGG: bja:blr2238 putative adenylate cyclase YP_001314350.1 KEGG: pen:PSEEN4433 subtilisin-like serine protease YP_001314351.1 KEGG: bja:blr6214 putative cytochrome c protein YP_001314353.1 PFAM: cyclic nucleotide-binding; KEGG: neu:NE1296 cyclic nucleotide-binding domain:cAMP-dependent protein kinase YP_001314354.1 PFAM: regulatory protein TetR; KEGG: ret:RHE_PC00210 probable transcriptional regulator protein, TetR family YP_001314355.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001314357.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rle:pRL110073 putative GntR family transcriptional regulator YP_001314358.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rde:RD1_0742 C4-dicarboxylate-binding protein, putative YP_001314359.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: pol:Bpro_2207 tripartite ATP-independent periplasmic transporter, DctQ component YP_001314360.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: jan:Jann_4136 TRAP dicarboxylate transporter-DctM subunit YP_001314361.1 PFAM: dehydroquinase class II; KEGG: rle:pRL110076 putative 3-dehydroquinate dehydratase YP_001314362.1 PFAM: protein of unknown function DUF1428; KEGG: sme:SMc01560 hypothetical protein YP_001314363.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rru:Rru_A3712 lysine exporter protein (LysE/YggA) YP_001314364.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: rle:RL3232 hypothetical protein YP_001314365.1 PFAM: regulatory protein MarR; KEGG: rle:RL3231 putative MarR family transcriptional regulator YP_001314366.1 PFAM: NmrA family protein; KEGG: ade:Adeh_1014 NmrA-like YP_001314368.1 PFAM: Integrase catalytic region; KEGG: atc:AGR_L_547 hypothetical protein YP_001314369.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_L_545 hypothetical protein YP_001314370.1 KEGG: sme:SMa1700 hypothetical protein YP_001314373.1 PFAM: Epoxide hydrolase domain protein; KEGG: bch:Bcen2424_3503 epoxide hydrolase domain protein YP_001314374.1 PFAM: aldehyde dehydrogenase; KEGG: rme:Rmet_1898 aldehyde dehydrogenase YP_001314375.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1632 putative LysR-family transcriptional regulator YP_001314376.1 KEGG: sme:SMc01549 hypothetical protein YP_001314377.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pde:Pden_3155 methyltransferase type 12 YP_001314378.1 KEGG: csa:Csal_1011 beta-lactamase-like protein YP_001314379.1 PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pfo:Pfl_2276 transcriptional regulatory protein-like YP_001314382.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMa1176 hypothetical protein YP_001314384.1 KEGG: rle:pRL100192 hypothetical protein YP_001314385.1 KEGG: rle:pRL100193 hypothetical protein YP_001314386.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mpt:Mpe_A1005 transcriptional regulatory protein YP_001314387.1 PFAM: HWE histidine kinase; KEGG: sme:SMa1696 hypothetical protein YP_001314388.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bld:BLi03843 ribose ABC transporter (ATP-binding protein); RBL02966 YP_001314389.1 KEGG: sme:SMa0067 putative ABC transporter, periplasmic solute-binding protein YP_001314390.1 PFAM: inner-membrane translocator; KEGG: tte:TTE0764 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_001314391.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sco:SCO0364 putative enoyl-CoA hydratase YP_001314392.1 KEGG: sco:SCO0363 putative integral membrane protein YP_001314393.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sco:SCO0362 racemase YP_001314394.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: rxy:Rxyl_0531 short-chain dehydrogenase/reductase SDR YP_001314395.1 KEGG: sco:SCO0366 hypothetical protein YP_001314396.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mlo:mll1734 hypothetical protein YP_001314397.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: mlo:mll1735 hypothetical protein YP_001314398.1 PFAM: regulatory protein LacI; KEGG: bxe:Bxe_B0437 transcriptional regulator, LacI family YP_001314399.1 SMART: response regulator receiver; KEGG: sme:SMa2065 hypothetical protein YP_001314400.1 PFAM: HWE histidine kinase; KEGG: sme:SMa2063 hypothetical protein YP_001314401.1 PFAM: Circadian clock protein KaiC central region; KaiA binding; SMART: AAA ATPase; KEGG: sme:SMa2061 hypothetical protein YP_001314402.1 PFAM: alpha/beta hydrolase fold; KEGG: mlo:mll5743 hypothetical protein YP_001314403.1 PFAM: OmpA/MotB domain protein; KEGG: sme:SMa0626 hypothetical protein YP_001314404.1 KEGG: rle:RL2260 hypothetical protein YP_001314405.1 KEGG: sme:SMa0627 aquaporin Z YP_001314406.1 PFAM: transposase IS3/IS911 family protein; KEGG: atu:Atu4891 IS 426 transposase YP_001314407.1 PFAM: sulfatase; KEGG: rle:pRL110221 putative arylsulfatase YP_001314408.1 KEGG: sme:SMa1682 NapD-like protein YP_001314409.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMa1680 hypothetical protein YP_001314410.1 KEGG: rle:RL2259 hypothetical protein YP_001314411.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMa0937 hypothetical protein YP_001314413.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: sme:SMa1903 putative protease YP_001314414.1 PFAM: CheB methylesterase; KEGG: sme:SMb20514 putative protein-glutamate methyltransferase protein YP_001314415.1 TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: sme:SMb20515 putative chemotaxis methyltransferase protein YP_001314416.1 KEGG: sme:SMb20516 putative response regulator protein YP_001314417.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ret:RHE_CH02595 probable acetyltransferase protein YP_001314418.1 KEGG: mlo:mlr3274 hypothetical protein YP_001314419.1 KEGG: bam:Bamb_5027 hypothetical protein YP_001314420.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: ret:RHE_PF00439 transcriptional regulator (activator) protein, LuxR family YP_001314422.1 PFAM: Asp/Glu racemase; KEGG: sme:SMc02427 putative hydantoin racemase protein YP_001314423.1 KEGG: sme:SMc02426 hypothetical protein YP_001314424.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc02425 putative transcription regulator protein YP_001314425.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc02424 putative oligopeptide transport ATP-binding ABC transporter protein YP_001314426.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc02423 putative oligopeptide transport ATP-binding ABC transporter protein YP_001314427.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline YP_001314428.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001314429.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02419 putative peptide transport system permease protein YP_001314430.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02418 putative peptide transport system permease ABC transporter protein YP_001314431.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc02417 putative peptide-binding periplasmic ABC transporter protein YP_001314432.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc02415 putative peptide-binding periplasmic ABC transporter protein YP_001314433.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMc02414 putative hydrolase protein YP_001314434.1 catalyzes the formation of 5-dehydro-D-gluconate from D-gluconate YP_001314435.1 PFAM: WGR domain protein; KEGG: atc:AGR_pAT_bx353 hypothetical protein YP_001314436.1 KEGG: nha:Nham_4512 hypothetical protein YP_001314437.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: nha:Nham_4513 prevent-host-death protein YP_001314438.1 PFAM: helix-turn-helix domain protein; KEGG: pde:Pden_1547 transcriptional regulator, XRE family YP_001314439.1 PFAM: HipA domain protein; KEGG: pde:Pden_1548 HipA domain protein YP_001314440.1 PFAM: Prophage CP4-57 regulatory; KEGG: mes:Meso_0497 phage transcriptional regulator, AlpA YP_001314441.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: bxe:Bxe_A3013 putative oxidoreductase, short-chain dehydrogenase/reductase YP_001314442.1 KEGG: sme:SMa0985 putative LysR-family transcriptional regulator YP_001314444.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: pfo:Pfl_2767 NADP oxidoreductase, coenzyme F420-dependent YP_001314445.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pfo:Pfl_2766 NADP oxidoreductase, coenzyme F420-dependent YP_001314446.1 PFAM: regulatory protein MarR; KEGG: pst:PSPTO_0818 transcriptional regulator, MarR family YP_001314448.1 PFAM: beta-lactamase domain protein; KEGG: atc:AGR_L_1113 hypothetical protein YP_001314449.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: sme:SMb20865 hypothetical protein YP_001314450.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMb20864 hypothetical protein YP_001314451.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMb20863 hypothetical protein YP_001314452.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMb20861 putative dehydrogenase, oxidoreductase FAD flavoprotein YP_001314453.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMb20860 putative non-heme haloperodidase, possibly chloroperoxidase protein YP_001314454.1 KEGG: sme:SMb21677 hypothetical exported protein signal peptide YP_001314455.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMb20859 putative transcriptional regulator, AraC family protein YP_001314456.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMb20871 putative dehydrogenasereductase, short-chain dehydrogenase/reductase protein YP_001314457.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20870 putative transcriptional regulator, LysR family protein YP_001314459.1 PFAM: Aldose 1-epimerase; KEGG: sme:SMa0077 hypothetical protein YP_001314460.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001314461.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa0072 putative ABC transporter ATP-binding protein YP_001314462.1 PFAM: inner-membrane translocator; KEGG: sme:SMa0070 putative ABC transporter permease YP_001314463.1 KEGG: sme:SMa0067 putative ABC transporter, periplasmic solute-binding protein YP_001314464.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0065 putative GntR-family transcriptional regulator YP_001314465.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMa0064 hypothetical protein YP_001314466.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0063 putative GntR-family transcriptional regulator YP_001314467.1 KEGG: rsp:RSP_4082 hypothetical protein YP_001314468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0062 putative GntR-family transcriptional regulator YP_001314469.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sme:SMa0060 putative regucalcin YP_001314470.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMa0059 hypothetical protein YP_001314471.1 PFAM: N-acylglucosamine 2-epimerase; KEGG: sme:SMa0058 hypothetical protein YP_001314472.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sus:Acid_2667 mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001314473.1 PFAM: regulatory protein TetR; KEGG: sme:SMa0190 hypothetical protein YP_001314474.1 KEGG: nfa:nfa27470 hypothetical protein YP_001314475.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: pau:PA14_53810 hypothetical protein YP_001314476.1 KEGG: sme:SMa0044 hypothetical protein YP_001314477.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMa0041 probable quinone oxidoreductase YP_001314478.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0039 probable LysR-family protein YP_001314479.1 KEGG: sme:SMc01337 hypothetical/unknown protein YP_001314480.1 PFAM: creatinase; peptidase M24; KEGG: sme:SMa1329 putative proline dipeptidase YP_001314481.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMa1331 hypothetical protein YP_001314482.1 KEGG: sme:SMa1332 hypothetical protein YP_001314483.1 PFAM: protein of unknown function UPF0261; KEGG: sme:SMa1334 hypothetical protein YP_001314484.1 PFAM: regulatory protein TetR; KEGG: ret:RHE_PF00373 probable transcriptional regulator protein, TetR family YP_001314485.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMa1337 putative sugar ABC transporter, periplasmic solute-binding protein YP_001314486.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1339 probable ABC transporter, permease protein YP_001314487.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1341 probable ABC transporter, permease protein YP_001314489.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMa1344 putative ABC transporter, ATP-binding protein YP_001314490.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMa1345 probable ABC transporter ATP-binding protein YP_001314491.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMa1347 putative phosphoglycerate dehydrogenase YP_001314492.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa1349 putative GntR-family transcriptional regulator YP_001314493.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ret:RHE_PF00381 putative mandelate racemase protein YP_001314494.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMa1353 putative epimerase YP_001314495.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMa1354 putative epimerase YP_001314496.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMa1497 putative Gst12 glutathione-S-transferase YP_001314497.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Rieske [2Fe-2S] domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa1500 putative oxidoreductase/oxygenase YP_001314498.1 KEGG: sme:SMa1501 hypothetical protein YP_001314499.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa1505 putative GntR-family transcriptional regulator YP_001314500.1 PFAM: basic membrane lipoprotein; KEGG: sme:SMa1507 hypothetical protein YP_001314501.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa1509 probable ATP transporter, ATP-binding protein YP_001314502.1 PFAM: inner-membrane translocator; KEGG: sme:SMa1513 putative ABC transporter permease YP_001314503.1 PFAM: inner-membrane translocator; KEGG: sme:SMa1514 putative ABC transporter permease YP_001314504.1 PFAM: DNA polymerase beta domain protein region; KEGG: pde:Pden_4803 adenylyltransferase YP_001314505.1 PFAM: major facilitator superfamily MFS_1; KEGG: mlo:mll7282 similar to multidrug-efflux transporter YP_001314506.1 PFAM: regulatory protein AsnC/Lrp family; LexA DNA-binding domain protein; KEGG: mlo:mlr7283 transcriptional regulator YP_001314507.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: atc:AGR_pAT_5 hypothetical protein YP_001314508.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_pAT_9 glutamine transport system permease proetin / ATP-binding proetin YP_001314509.1 PFAM: extracellular solute-binding protein family 3; KEGG: atc:AGR_pAT_12 GlnH homolog YP_001314510.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_pAT_13 transcriptional repressor YP_001314511.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA2152 hypothetical protein YP_001314512.1 PFAM: putative sugar-binding domain protein; KEGG: sme:SMb20619 putative regulatory protein YP_001314513.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20620 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_001314514.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20621 putative sugar uptake ABC transporter permease protein YP_001314515.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20622 putative sugar uptake ABC transporter ATP-binding protein YP_001314516.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_001314517.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001314518.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa2341 putative LysR-family transcriptional regulator YP_001314519.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa2343 putative oxidoreductase YP_001314520.1 KEGG: hne:HNE_0020 hypothetical protein YP_001314521.1 PFAM: Rieske [2Fe-2S] domain protein; FAD dependent oxidoreductase; KEGG: sme:SMc02428 putative oxidoreductase protein YP_001314522.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; KEGG: mlo:mlr9681 sensory transduction histidine kinase YP_001314523.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMa2069 probable ABC transporter, sulfate-binding protein YP_001314524.1 KEGG: sme:SMa2299 hypothetical protein YP_001314526.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sme:SMb21550 hypothetical protein YP_001314527.1 PFAM: Rhodanese domain protein; KEGG: sme:SMb21549 putative exported sulfurtransferase, rhodanese protein YP_001314528.1 PFAM: UvrD/REP helicase; KEGG: sme:SMa2321 putative UvrD2 DNA helicase YP_001314529.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pfl:PFL_2331 transcriptional regulator, LysR family YP_001314530.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: vei:Veis_2905 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001314531.1 PFAM: Dimethylmenaquinone methyltransferase; KEGG: bpa:BPP1802 hypothetical protein YP_001314532.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20724 putative tricarboxylic transport membrane protein YP_001314533.1 KEGG: atc:AGR_C_4484 putative tricarboxylic transport membrane protein YP_001314534.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: dge:Dgeo_0831 protein of unknown function DUF112, transmembrane YP_001314535.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: oih:OB2846 malate dehydrogenase YP_001314536.1 PFAM: globin; KEGG: sme:SMc02351 hypothetical protein YP_001314537.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: trehalose-phosphatase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: rsp:RSP_0949 putative trehalose-6-phosphate phosphatase YP_001314538.1 TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase family 20; KEGG: sme:SMa0233 probable OtsA trehalose-6-phosphate synthase YP_001314539.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa0036 putative ABC transporter ATP-binding protein YP_001314540.1 KEGG: mbb:BCG_0404c hypothetical protein YP_001314541.1 KEGG: hch:HCH_00187 hypothetical protein YP_001314542.1 KEGG: sme:SMa1201 hypothetical protein YP_001314543.1 KEGG: rle:RL0531 putative transmembrane protein YP_001314544.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sme:SMa0622 FixS2 nitrogen fixation protein YP_001314545.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sme:SMa0621 FixI2 E1-E2 type cation ATPase YP_001314546.1 KEGG: sme:SMa0620 hypothetical protein YP_001314548.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: sme:SMa0617 FixP3 cytochrome c oxidase membrane anchored subunit YP_001314549.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sme:SMa0616 FixQ3 nitrogen fixation protein YP_001314550.1 CcoO; FixO YP_001314551.1 CcoN; FixN YP_001314552.1 PFAM: cyclic nucleotide-binding; KEGG: sme:SMa1207 FixK-like regulatory protein YP_001314553.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sme:SMa1208 FixS1 nitrogen fixation protein YP_001314554.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sme:SMa1209 FixI1 copper transport ATPase YP_001314555.1 PFAM: FixH family protein; KEGG: sme:SMa1210 FixH nitrogen fixation protein YP_001314556.1 TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; KEGG: sme:SMa1211 FixG iron sulfur membrane protein YP_001314557.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: sme:SMa1213 FixP1 Di-heme cytochrome c YP_001314558.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sme:SMa1214 FixQ1 cbb3-type cytochrome oxidase YP_001314559.1 CcoO; FixO YP_001314560.1 CcoN; FixN YP_001314561.1 KEGG: sme:SMa0760 FixT2 transcription regulator YP_001314562.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMa0753 hypothetical protein with localized conservation YP_001314563.1 KEGG: rle:pRL100167 putative transposase YP_001314564.1 KEGG: nha:Nham_4600 feruloyl esterase YP_001314565.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0757 NodD2 nod box-dependent transcription activator YP_001314568.1 PFAM: LysR substrate-binding; KEGG: rle:pRL120548 putative LysR family transcriptional regulator YP_001314569.1 PFAM: virulence factor family protein; KEGG: atc:AGR_C_4582 virulence gene acvB product YP_001314570.1 PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; KEGG: sme:SMc00611 hypothetical transmembrane protein YP_001314571.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: rpa:RPA2432 putative signal transduction histidine kinase with response regulator receiver domain YP_001314572.1 PFAM: response regulator receiver; KEGG: rpc:RPC_2871 response regulator receiver domain protein (CheY-like) YP_001314573.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rpd:RPD_2430 ATP-binding region, ATPase-like YP_001314574.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: mca:MCA2474 sigma-54 dependent DNA-binding response regulator YP_001314575.1 PFAM: protein of unknown function DUF1614; KEGG: mtp:Mthe_0756 protein of unknown function DUF1614 YP_001314576.1 PFAM: protein of unknown function DUF1003; KEGG: mlo:mlr0821 hypothetical protein YP_001314578.1 KEGG: mlo:mlr8178 hypothetical protein YP_001314579.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: rle:pRL120675 hypothetical protein YP_001314580.1 KEGG: eli:ELI_14595 hypothetical protein YP_001314581.1 KEGG: mlo:mlr9230 hypothetical protein YP_001314582.1 PFAM: WGR domain protein; KEGG: rle:pRL100216 hypothetical protein YP_001314583.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: hch:HCH_02020 predicted transcriptional regulator YP_001314584.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: pfl:PFL_2854 lipoprotein, putative YP_001314586.1 KEGG: nwi:Nwi_2847 probable ISRm2011-2 transposase protein YP_001314587.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMa0753 hypothetical protein with localized conservation YP_001314588.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit YP_001314589.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMa0751 putative aromatic-ring hydroxylating dioxygenase, alpha-subunit YP_001314590.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0750 probable LysR-family transcriptional activator YP_001314591.1 KEGG: rle:RL1148 hypothetical protein YP_001314593.1 PFAM: glycoside hydrolase 15-related; KEGG: ret:RHE_PF00442 putative glucoamylase protein YP_001314594.1 KEGG: ret:RHE_PF00443 putative dehydrogenase large subunit protein YP_001314595.1 KEGG: ret:RHE_PF00444 hypothetical protein YP_001314596.1 KEGG: ret:RHE_PF00445 hypothetical protein YP_001314597.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ret:RHE_PF00446 probable myo-inositol catabolism protein YP_001314598.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ret:RHE_PF00447 hypothetical protein YP_001314599.1 PFAM: beta-lactamase domain protein; KEGG: ret:RHE_PF00448 putative metallo-beta-lactamase superfamily protein YP_001314600.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: ret:RHE_PF00449 putative pyruvate decarboxylase protein YP_001314601.1 PFAM: ROSMUCR transcriptional regulator; KEGG: sme:SMa0748 putative MucR family transcriptional regulatory protein YP_001314604.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sme:SMc04263 putative amino acid carrier transmembrane protein YP_001314606.1 PFAM: NUDIX hydrolase; KEGG: ret:RHE_CH00948 putative NTP pyrophosphohydrolase protein, MuT/NUDIX family YP_001314608.1 PFAM: Integrase catalytic region; KEGG: sme:SMc03283 putative transposase for insertion sequence ISRM18 YP_001314609.1 KEGG: rle:pRL70076 5.1.4 YP_001314610.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001314611.1 PFAM: glutamine synthetase catalytic region; KEGG: atc:AGR_L_1262 glutamine synthetase III (glutamate--ammonia ligase III) (GSIII) YP_001314612.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; dihydroorotate dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: rle:pRL110555 putative glutamate synthase [NADPH] large chain precursor YP_001314613.1 PFAM: glutamate synthase alpha subunit domain protein; KEGG: atc:AGR_L_1266 putative oxidoreductase protein YP_001314614.1 PFAM: glutamine amidotransferase class-II; KEGG: atc:AGR_L_1268 hypothetical protein YP_001314615.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: atc:AGR_L_1270 hypothetical protein YP_001314617.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: gox:GOX1386 hypothetical protein YP_001314619.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_L_545 hypothetical protein YP_001314622.1 KEGG: sme:SMb20783 putative transposase of insertion sequence ISRm2011-2, orfA protein YP_001314623.1 PFAM: ROSMUCR transcriptional regulator; KEGG: sme:SMa0748 putative MucR family transcriptional regulatory protein YP_001314624.1 PFAM: oxidoreductase molybdopterin binding; KEGG: ret:RHE_CH02958 putative sulfite oxidase protein YP_001314625.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: atu:Atu4018 two component sensor kinase YP_001314626.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rsp:RSP_3088 two component transcriptional regulator, winged helix family YP_001314627.1 KEGG: maq:Maqu_3215 hypothetical protein YP_001314628.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: atc:AGR_L_1668 putative membrane protein YP_001314629.1 PFAM: transposase mutator type; KEGG: sme:SMa1356 TRm3 transposase YP_001314630.1 KEGG: maq:Maqu_3215 hypothetical protein YP_001314631.1 PFAM: cytochrome B561; KEGG: ajs:Ajs_0510 cytochrome b561 YP_001314633.1 PFAM: K potassium transporter; KEGG: sme:SMa1798 Kup2 potassium uptake protein YP_001314635.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMa0753 hypothetical protein with localized conservation YP_001314636.1 KEGG: rle:RL1148 hypothetical protein YP_001314638.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ret:RHE_PF00449 putative pyruvate decarboxylase protein YP_001314639.1 KEGG: mlo:msl9199 hypothetical protein YP_001314640.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sma:SAV1553 methyltransferase YP_001314641.1 PFAM: ROSMUCR transcriptional regulator; KEGG: sme:SMa0748 putative MucR family transcriptional regulatory protein YP_001314644.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sme:SMc04263 putative amino acid carrier transmembrane protein YP_001314646.1 PFAM: NUDIX hydrolase; KEGG: ret:RHE_CH00948 putative NTP pyrophosphohydrolase protein, MuT/NUDIX family YP_001314648.1 PFAM: Cold-shock protein DNA-binding; Ribonuclease B OB region domain; SMART: Cold shock protein; KEGG: sme:SMa0738 probable CspA6 cold shock protein transcriptional regulator YP_001314650.1 KEGG: atc:AGR_C_824 hypothetical protein YP_001314651.1 KEGG: sme:SMb20921 hypothetical protein YP_001314652.1 KEGG: sme:SMb21395 hypothetical protein YP_001314653.1 KEGG: sme:SMb21396 hypothetical protein YP_001314654.1 KEGG: sme:SMb21396 hypothetical protein YP_001314655.1 PFAM: helix-turn-helix domain protein; KEGG: ret:RHE_CH00142 putative transcriptional regulator protein, Cro/CI family YP_001314658.1 KEGG: sme:SMb21026 hypothetical exopeptide protein YP_001314659.1 TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine-binding; KEGG: rpe:RPE_3305 acyl carrier protein YP_001314660.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001314661.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001314662.1 SMART: nuclease (SNase domain protein); KEGG: sme:SMb21662 putative periplasmic protein YP_001314663.1 PFAM: peptidase C1A papain; KEGG: cph:Cpha266_2670 peptidase C1A, papain YP_001314664.1 PFAM: Lanthionine synthetase C family protein; KEGG: pmf:P9303_21071 possible MrsD-like protein YP_001314666.1 TIGRFAM: yecA family protein; KEGG: sme:SMc03284 hypothetical/unknown protein YP_001314667.1 PFAM: transposase IS66; KEGG: bms:BRA0556 IS66 family element, orf3, putative YP_001314668.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: sme:SMb21045 putative reverse transcriptasematurase protein YP_001314670.1 PFAM: transposase IS66; KEGG: sme:SMc03280 putative transposase number 3 for insertion sequence ISRM28 YP_001314671.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMc03279 putative transposase number 2 for insertion sequence ISRM28 YP_001314673.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: aav:Aave_2380 methyltransferase type 11 YP_001314674.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001314675.1 PFAM: thiamineS protein; KEGG: cya:CYA_0300 MoaD family protein YP_001314678.1 PFAM: protein of unknown function DUF181; KEGG: mtp:Mthe_1401 uncharacterized domain protein YP_001314679.1 PFAM: TfuA domain protein core; KEGG: mxa:MXAN_2398 hypothetical protein YP_001314680.1 PFAM: protein of unknown function DUF181; KEGG: pde:Pden_3472 hypothetical protein YP_001314685.1 KEGG: nha:Nham_4172 ISSpo6, transposase orf A YP_001314687.1 KEGG: bms:BR0533 ISBm1, transposase orfA YP_001314688.1 KEGG: pst:PSPTO_4873 hypothetical protein YP_001314689.1 KEGG: pst:PSPTO_4873 hypothetical protein YP_001314690.1 PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL70144 putative insertion sequence protein YP_001314692.1 PFAM: Integrase catalytic region; KEGG: sus:Acid_6862 integrase, catalytic region YP_001314693.1 KEGG: bja:blr8219 putative transposase YP_001314695.1 PFAM: tyrosinase; KEGG: nmu:Nmul_A0920 tyrosinase YP_001314696.1 KEGG: nha:Nham_1020 hypothetical protein YP_001314697.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: hch:HCH_03584 putative multicopper oxidases YP_001314698.1 KEGG: sme:SMb21395 hypothetical protein YP_001314699.1 PFAM: helix-turn-helix domain protein; KEGG: ret:RHE_CH00142 putative transcriptional regulator protein, Cro/CI family YP_001314700.1 KEGG: bms:BR0533 ISBm1, transposase orfA YP_001314701.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: ret:RHE_PF00141 putative kinase protein YP_001314702.1 PFAM: Pectate lyase/Amb allergen; KEGG: xcb:XC_3591 pectate lyase YP_001314703.1 PFAM: carbonic anhydrase; KEGG: sme:SMa0045 probable carbonic anhydrase, Cah YP_001314704.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20891 putative dehydrogenase, possibly aldehyde dehydrogenase protein YP_001314705.1 KEGG: rle:pRL70127 hypothetical protein YP_001314706.1 coupling protein TraG/VirD4 family YP_001314707.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: atc:AGR_pTi_15 probable virG gene YP_001314708.1 KEGG: sme:SMb21224 putative sulfate adenylyltransferase subunit 1 adenylsulfate kinase protein YP_001314709.1 KEGG: ret:RHE_PA00037 hypothetical protein YP_001314710.1 KEGG: gox:GOX2729 transposase YP_001314711.1 ATPase YP_001314712.1 PFAM: conjugation TrbI family protein; KEGG: atc:AGR_pTi_13 probable virB10 gene YP_001314713.1 TIGRFAM: P-type conjugative transfer protein VirB9; PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: atc:AGR_pTi_12 probable virB9 gene YP_001314714.1 PFAM: VirB8 family protein; KEGG: atc:AGR_pTi_11 probable virB8 gene YP_001314715.1 KEGG: atc:AGR_pTi_missing T-DNA transfer lipoprotein (virB7) YP_001314716.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: atc:AGR_pTi_10 virB6 protein YP_001314717.1 KEGG: atc:AGR_pTi_9 probable virB5 gene YP_001314718.1 TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE TrbE VirB component of type IV transporter system; KEGG: atc:AGR_pTi_8 VIRB4 protein precursor YP_001314719.1 PFAM: type IV secretory pathway VirB3 family protein; KEGG: atc:AGR_pTi_bx137 T-DNA transfer exported protein (virB3) YP_001314720.1 PFAM: VIRB2 type IV secretion fmaily protein; KEGG: atc:AGR_pTi_4 probable virB2 gene YP_001314721.1 PFAM: Lytic transglycosylase catalytic; KEGG: atc:AGR_pTi_3 ORF1 (virB1) (AA 1 - 252) YP_001314723.1 KEGG: nha:Nham_4600 feruloyl esterase YP_001314724.1 KEGG: bms:BR0533 ISBm1, transposase orfA YP_001314725.1 KEGG: bms:BR0533 ISBm1, transposase orfA YP_001314728.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001314729.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMa0876 NolF secretion protein YP_001314730.1 PFAM: acriflavin resistance protein; KEGG: sme:SMa0875 NolG efflux transporter YP_001314731.1 functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001314732.1 KEGG: sme:SMa0872 hypothetical protein ORF 110 YP_001314733.1 PFAM: regulatory protein LysR; KEGG: sme:SMa0870 NodD1 transcription regulator YP_001314734.1 catalyzes the transfer of a fatty acyl group onto Nod factor, beta-(1,4)-N-acetylglucosamine oligosaccharide YP_001314735.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMa0868 NodB chitooligosaccharide deacetylase YP_001314736.1 PFAM: glycosyl transferase family 2; chitin synthase; KEGG: sme:SMa0866 NodC N-acetylglucosaminyltransferase YP_001314737.1 ATP-binding subunit; with NodJ is involved in the export of lipo-chitin oligosaccharide; involved in nodulation induction YP_001314738.1 TIGRFAM: ABC-2 type transporter, NodJ family; PFAM: ABC-2 type transporter; KEGG: sme:SMa0863 NodJ membrane transport protein YP_001314739.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_001314740.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001314741.1 catalyzes the formation of 3-hydroxyacyl-ACP from 3-keto-acyl-ACP; in the rhizobia this protein interacts with NodF to allow for the synthesis of highly polyunsaturated fatty acids necessary for nodulation YP_001314742.1 PFAM: Beta-ketoacyl synthase; KEGG: sme:SMa0853 NodE beta ketoacyl ACP synthase YP_001314743.1 KEGG: sme:SMa0852 NodF acyl carrier protein YP_001314744.1 KEGG: sme:SMa0851 NodH sulfotransferase YP_001314745.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03301 putative transposase number 1 for insertion sequence ISRM26 YP_001314746.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMc03300 putative transposase number 2 for insertion sequence ISRM26 YP_001314747.1 PFAM: transposase IS66; KEGG: sme:SMc03298 putative transposase number 3 for insertion sequence ISRM26 YP_001314748.1 PFAM: phage integrase family protein; KEGG: sus:Acid_3311 phage integrase family protein YP_001314749.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0849 SyrM transcriptional regulator YP_001314750.1 KEGG: sme:SMa0848 hypothetical protein YP_001314753.1 PFAM: regulatory protein LysR; KEGG: sme:SMa0840 NodD3 transcriptional regulator YP_001314754.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_4315 transposase IS116/IS110/IS902 YP_001314755.1 KEGG: sme:SMa0838 SyrA protein involved in EPS production YP_001314756.1 TIGRFAM: Ferredoxin III 4[4Fe-4S] nif-specific; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sme:SMa0834 FdxB ferredoxin III YP_001314757.1 PFAM: protein of unknown function DUF683; KEGG: mlo:msr5868 hypothetical protein YP_001314758.1 TIGRFAM: nitrogen fixation protein NifX; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: sme:SMa0831 NifX nitrogen fixation protein YP_001314759.1 functions with NifN to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001314760.1 TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: oxidoreductase/nitrogenase component 1; KEGG: sme:SMa0829 NifK nitrogenase Fe-Mo beta chain YP_001314761.1 TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase component 1; KEGG: sme:SMa0827 NifD nitrogenase Fe-Mo alpha chain YP_001314762.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; in R. etli there are three essentially identical copies of nifH which are actively expressed during symbiosis YP_001314763.1 KEGG: sme:SMa0824 hypothetical protein YP_001314764.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: sme:SMa0822 FixA electron transfer flavoprotein beta chain YP_001314765.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: sme:SMa0819 FixB electron transfer flavoprotein alpha chain YP_001314766.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMa0817 FixC oxidoreductase YP_001314767.1 KEGG: sme:SMa0816 FixX ferredoxin-like protein YP_001314768.1 TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sme:SMa0815 NifA transcriptional activator YP_001314769.1 TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein; KEGG: sme:SMa0814 NifB FeMo cofactor biosynthesis protein YP_001314770.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sme:SMa0811 FdxN ferredoxin YP_001314771.1 PFAM: NifT/FixU family protein; KEGG: sme:SMa0810 FixU nitrogen fixation protein YP_001314772.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMb20935 putative transcriptional regulator protein YP_001314773.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: mlo:mll9195 transposase YP_001314774.1 PFAM: Integrase catalytic region; KEGG: atc:AGR_L_547 hypothetical protein YP_001314775.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_L_545 hypothetical protein YP_001314776.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMa0806 probable SyrB-like regulator YP_001314777.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sme:SMa0805 GabD4 succinate-semialdehyde dehdyrogenase YP_001314778.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMa0803 putative ABC-transporter ATP-binding protein YP_001314779.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0802 putative ABC transporter, permease protein YP_001314780.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0800 putative ABC transporter, permease protein YP_001314781.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMa0799 putative ABC transporter, periplasmic solute-binding protein YP_001314782.1 PFAM: NIPSNAP family containing protein; KEGG: sme:SMa0797 hypothetical protein YP_001314783.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMa0796 probable aldehyde dehydrogenase YP_001314784.1 PFAM: luciferase family protein; KEGG: sme:SMa0794 hypothetical protein YP_001314785.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMa0793 hypothetical protein with local similarity YP_001314786.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMa0792 hypothetical protein with local similarity YP_001314787.1 PFAM: protein of unknown function DUF1185; KEGG: sme:SMa0791 hypothetical protein with local similarity YP_001314788.1 KEGG: sme:SMa0790 hypothetical protein YP_001314789.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: atc:AGR_L_1259 hypothetical protein YP_001314790.1 KEGG: nha:Nham_4172 ISSpo6, transposase orf A YP_001314791.1 KEGG: gox:GOX2729 transposase YP_001314792.1 KEGG: sme:SMa0774 NoeB host specific nodulation protein YP_001314793.1 KEGG: sme:SMa0773 NoeA host specific nodulation protein YP_001314795.1 KEGG: sme:SMa0772 NodL Nod factor acetyltransferase YP_001314796.1 PFAM: Heavy metal transport/detoxification protein; KEGG: sme:SMa1209 FixI1 copper transport ATPase YP_001314797.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: sme:SMa1213 FixP1 Di-heme cytochrome c YP_001314798.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sme:SMa1214 FixQ1 cbb3-type cytochrome oxidase YP_001314799.1 CcoO; FixO YP_001314800.1 CcoN; FixN YP_001314801.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: sme:SMa1223 conserved hypothetical protein (ORF151) YP_001314802.1 transcriptional regulator that positively regulated fixLJ operon; upregulated transcription by FixJ; part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes YP_001314803.1 PFAM: transposase IS111A/IS1328/IS1533; KEGG: hne:HNE_3101 ISHne5, transposase YP_001314804.1 response regulator for histidine kinase FixL; part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes YP_001314805.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sme:SMa1229 FixL oxygen regulated histidine kinase YP_001314806.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: sme:SMa1243 Azu1 pseudoazurin (blue copper protein) YP_001314807.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: sme:SMa1245 putative crp/fnr-like transcriptional regulator YP_001314808.1 PFAM: protein of unknown function DUF323; KEGG: sme:SMa1247 NirV periplasmic nitrate reductase YP_001314809.1 TIGRFAM: nitrite reductase, copper-containing; PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sme:SMa1250 putative NirK Cu-nitrite reductase YP_001314810.1 PFAM: NnrS family protein; KEGG: sme:SMa1252 putative uncharacterized protein involved in response to NO YP_001314811.1 PFAM: protein of unknown function DUF59; KEGG: sme:SMa1255 hypothetical protein YP_001314812.1 KEGG: sme:SMa1256 hypothetical protein YP_001314813.1 KEGG: sme:SMa1259 hypothetical protein YP_001314814.1 KEGG: sme:SMa1261 hypothetical protein YP_001314815.1 KEGG: bmb:BruAb1_0666 hypothetical protein YP_001314816.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001314817.1 PFAM: von Willebrand factor type A; KEGG: sme:SMa1269 NorD protein required for nitric oxide reductase (Nor) activity YP_001314818.1 PFAM: ATPase associated with various cellular activities AAA_5; CbbQ/NirQ/NorQ domain protein; KEGG: sme:SMa1272 NorQ protein required for nitric oxide reductase activity YP_001314819.1 PFAM: cytochrome c oxidase subunit I; KEGG: sme:SMa1273 NorB nitric oxide reductase YP_001314820.1 PFAM: cytochrome c class I; KEGG: sme:SMa1276 NorC nitric oxide reductase YP_001314821.1 KEGG: bja:bsr3213 hypothetical protein YP_001314822.1 PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMa1279 NorE protein involved in nitric oxide reduction YP_001314823.1 KEGG: atc:AGR_L_947 hypothetical protein YP_001314824.1 KEGG: rle:pRL90022 hypothetical protein YP_001314825.1 PFAM: NnrUfamily protein; KEGG: sme:SMa1283 probable NnrU protein YP_001314826.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001314827.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: sme:SMa1288 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001314828.1 KEGG: sme:SMa1289 hypothetical protein YP_001314829.1 PFAM: peptidase U32; KEGG: sme:SMa1291 probable proteinase YP_001314830.1 KEGG: sme:SMa1294 hypothetical protein YP_001314832.1 KEGG: sme:SMc02590 hypothetical protein YP_001314833.1 KEGG: sme:SMc02591 hypothetical protein YP_001314834.1 KEGG: sme:SMc02592 hypothetical protein YP_001314835.1 KEGG: sme:SMc02593 hypothetical protein YP_001314836.1 KEGG: mag:amb3605 hypothetical protein YP_001314837.1 KEGG: sme:SMa0403 hypothetical protein YP_001314838.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMa0402 putative GntR-type regulator YP_001314839.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMa0400 putative zinc-binding YP_001314840.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001314841.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0396 putative ABC transporter, permease YP_001314842.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0394 putative ABC transporter, permease YP_001314843.1 KEGG: sme:SMa0392 ABC transporter, periplasmic solute-binding protein YP_001314844.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMa0391 putative ABC transporter, ATP-binding protein YP_001314845.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMa0389 putative dehydrogenase YP_001314846.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate and L-glutamate from L-histidinol phosphate and 2-oxoglutarate YP_001314847.1 KEGG: mes:Meso_0173 hypothetical protein YP_001314848.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: btl:BALH_3308 transcriptional regulator, LysR family YP_001314849.1 KEGG: sme:SMc00591 hypothetical/unknown signal peptide protein YP_001314850.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: aha:AHA_3966 DNA-binding response regulator YP_001314852.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pde:Pden_3232 histidine kinase YP_001314853.1 PFAM: cytochrome c class I; KEGG: sme:SMa1487 probable C-type cytochrome YP_001314854.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hne:HNE_2483 putative isoquinoline 1-oxidoreductase, alpha subunit YP_001314855.1 KEGG: sme:SMa1833 probable L-sorbosone dehydrogenase YP_001314856.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1602 putative LysR-family transcriptional regulator YP_001314857.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sme:SMa1604 putative oxidoreductase YP_001314858.1 KEGG: bja:bll1417 hypothetical protein YP_001314860.1 PFAM: glycoside hydrolase family 25; KEGG: bms:BRA0487 glycosyl hydrolase, family 25 YP_001314863.1 PFAM: homocysteine S-methyltransferase; KEGG: mes:Meso_0624 homocysteine S-methyltransferase YP_001314864.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03250 hypothetical protein YP_001314865.1 PFAM: IS66 Orf2 family protein; KEGG: nha:Nham_3807 IS66 Orf2 like YP_001314866.1 PFAM: transposase IS66; KEGG: nha:Nham_2793 transposase IS66 YP_001314867.1 TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; PAS fold domain protein; KEGG: ret:RHE_PF00076 chemotaxis methyltransferase protein YP_001314868.1 PFAM: CheB methylesterase; MCP methyltransferase CheR-type; KEGG: rfr:Rfer_2355 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor YP_001314870.1 KEGG: sme:SMa1875 putative reverse transcriptase YP_001314871.1 PFAM: transposase mutator type; KEGG: rpc:RPC_3939 transposase, mutator type YP_001314872.1 PFAM: protein of unknown function DUF1452; KEGG: sme:SMb21472 hypothetical protein YP_001314873.1 KEGG: sme:SMb21683 hypothetical protein YP_001314874.1 PFAM: MgtC/SapB transporter; KEGG: sus:Acid_7726 MgtC/SapB transporter YP_001314875.1 KEGG: rpc:RPC_3624 hypothetical protein YP_001314876.1 PFAM: Pyrrolo-quinoline quinone; KEGG: sus:Acid_6912 pyrrolo-quinoline quinone YP_001314877.1 SMART: extracellular solute-binding protein family 3; KEGG: sus:Acid_6911 extracellular solute-binding protein, family 3 YP_001314878.1 PFAM: cytochrome c class I; KEGG: mlo:mll9632 cytochrome c oxidase subunit III YP_001314879.1 TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; KEGG: ret:RHE_PB00065 probable cytochrome c oxidase subunit II protein YP_001314880.1 TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I; KEGG: ret:RHE_PB00064 probable cytochrome c oxidase subunit I protein YP_001314881.1 KEGG: ret:RHE_PB00063 putative cytochrome c oxidase subunit III protein YP_001314882.1 KEGG: sus:Acid_6906 hypothetical protein YP_001314883.1 KEGG: sus:Acid_6905 hypothetical protein YP_001314884.1 KEGG: sme:SMb21396 hypothetical protein YP_001314886.1 TIGRFAM: yecA family protein; KEGG: sme:SMc03284 hypothetical/unknown protein YP_001314887.1 PFAM: transposase IS66; KEGG: bms:BRA0556 IS66 family element, orf3, putative YP_001314888.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMc03279 putative transposase number 2 for insertion sequence ISRM28 YP_001314889.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03278 putative transposase number 1 for insertion sequence ISRM28 YP_001314890.1 PFAM: polysaccharide biosynthesis protein; KEGG: sme:SMb21244 putative membrane protein, similar to putative polysaccharide transporter YP_001314891.1 PFAM: K potassium transporter; KEGG: sme:SMa1798 Kup2 potassium uptake protein YP_001314892.1 PFAM: ROSMUCR transcriptional regulator; KEGG: sme:SMa0748 putative MucR family transcriptional regulatory protein YP_001314893.1 KEGG: sme:SMa1697 hypothetical protein YP_001314894.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMb20935 putative transcriptional regulator protein YP_001314896.1 PFAM: helix-turn-helix domain protein; KEGG: mes:Meso_4238 transcriptional regulator, XRE family YP_001314897.1 KEGG: mes:Meso_4163 hypothetical protein YP_001314898.1 KEGG: mes:Meso_4164 hypothetical protein YP_001314899.1 PFAM: mobilisation protein; KEGG: mes:Meso_4165 hypothetical protein YP_001314900.1 KEGG: mes:Meso_4166 hypothetical protein YP_001314902.1 PFAM: protein of unknown function DUF1486; KEGG: gvi:glr0227 hypothetical protein YP_001314903.1 PFAM: beta-lactamase domain protein; KEGG: mes:Meso_3529 beta-lactamase-like YP_001314904.1 PFAM: manganese containing catalase; KEGG: rba:RB10727 manganese-containing catalase YP_001314905.1 KEGG: ret:RHE_PF00060 hypothetical protein YP_001314907.1 PFAM: protein of unknown function DUF1214; KEGG: mkm:Mkms_3213 protein of unknown function DUF1214 YP_001314908.1 PFAM: TRAG family protein; KEGG: mes:Meso_4169 TraG protein YP_001314909.1 TIGRFAM: P-type DNA transfer ATPase VirB11; PFAM: type II secretion system protein E; KEGG: mes:Meso_4170 type II secretion system protein E YP_001314910.1 PFAM: conjugation TrbI family protein; KEGG: mes:Meso_4171 conjugation TrbI-like protein YP_001314911.1 TIGRFAM: P-type conjugative transfer protein VirB9; PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: mes:Meso_4172 conjugal transfer protein TrbG/VirB9/CagX YP_001314912.1 PFAM: VirB8 family protein; KEGG: mes:Meso_4173 VirB8 YP_001314913.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: mes:Meso_4174 TrbL/VirB6 plasmid conjugal transfer protein YP_001314915.1 KEGG: mes:Meso_4175 conjugal transfer protein YP_001314916.1 PFAM: Lytic transglycosylase catalytic; KEGG: mes:Meso_4176 lytic transglycosylase, catalytic YP_001314917.1 TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE TrbE VirB component of type IV transporter system; KEGG: mes:Meso_4177 type IV secretion/conjugal transfer ATPase, VirB4 family YP_001314918.1 PFAM: type IV secretory pathway VirB3 family protein; KEGG: mes:Meso_4178 type IV secretory pathway, VirB3-like YP_001314919.1 PFAM: VIRB2 type IV secretion fmaily protein; KEGG: mes:Meso_4179 VirB2 type IV secretion YP_001314920.1 PFAM: Lytic transglycosylase catalytic; KEGG: mes:Meso_4180 lytic transglycosylase, catalytic YP_001314921.1 KEGG: mes:Meso_4181 hypothetical protein YP_001314922.1 KEGG: mes:Meso_4182 succinoglycan biosynthesis protein ExoI-like YP_001314923.1 PFAM: nuclease (SNase domain protein); KEGG: mes:Meso_4183 nuclease (SNase-like) YP_001314925.1 KEGG: mes:Meso_4184 hypothetical protein YP_001314929.1 KEGG: rle:pRL80128 hypothetical protein YP_001314930.1 KEGG: rle:pRL80130 putative transmembrane protein YP_001314932.1 PFAM: Integrase catalytic region; KEGG: sme:SMa2047 TRm24 putative transposase YP_001314933.1 KEGG: sme:SMc01196 hypothetical protein YP_001314934.1 PFAM: Integrase catalytic region; KEGG: ret:RHE_PA00137 putative insertion sequence transposase protein YP_001314937.1 PFAM: tyrosinase; KEGG: nmu:Nmul_A0920 tyrosinase YP_001314938.1 KEGG: bur:Bcep18194_C6987 hypothetical protein YP_001314939.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: hch:HCH_03584 putative multicopper oxidases YP_001314940.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02119 probable general L-amino acid transport permease ABC transporter protein YP_001314941.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02120 probable general L-amino acid transport permease ABC transporter protein YP_001314942.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02121 probable general L-amino acid transport ATP-binding ABC transporter protein YP_001314945.1 KEGG: sme:SMc02709 hypothetical/unknown protein YP_001314946.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: bxe:Bxe_B1680 Ca2+/H+ antiporter, CaCA family YP_001314948.1 PFAM: plasmid stabilization system; KEGG: rle:pRL120676 hypothetical protein YP_001314949.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: rle:pRL120675 hypothetical protein YP_001314950.1 KEGG: gox:GOX2729 transposase YP_001314951.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: IS1111A/IS1328/IS1533 family transposase; K07486 transposase YP_001314952.1 KEGG: nha:Nham_4600 feruloyl esterase YP_001314953.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate YP_001314954.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: bja:bll0240 transcriptional regulatory protein YP_001314955.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03301 putative transposase number 1 for insertion sequence ISRM26 YP_001314956.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: sus:Acid_7643 phage integrase family protein YP_001314957.1 PFAM: phage integrase family protein; KEGG: mlo:mll6043 integrase/recombinase YP_001314958.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding domain protein; SMART: AAA ATPase; KEGG: sme:SMa0776 TRm23b IS ATP-binding protein YP_001314959.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: bja:bll2236 putative 4'-phosphopantetheinyl transferase YP_001314960.1 KEGG: mlo:mlr4158 hypothetical protein YP_001314961.1 KEGG: plu:plu4884 hypothetical protein YP_001314962.1 KEGG: rpb:RPB_4281 hypothetical protein YP_001314963.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: plu:plu2670 hypothetical protein YP_001314964.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: psb:Psyr_2616 amino acid adenylation YP_001314966.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ret:RHE_PE00064 probable transcriptional regulator protein, LysR family YP_001314967.1 KEGG: mlo:mlr6364 cytochrome P-450 YP_001314968.1 KEGG: nha:Nham_4600 feruloyl esterase YP_001314969.1 KEGG: bms:BR0533 ISBm1, transposase orfA YP_001314971.1 TIGRFAM: putative addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: mlo:mlr9262 hypothetical protein YP_001314972.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: mlo:msr9263 hypothetical protein YP_001314973.1 KEGG: ret:RHE_PA00097 hypothetical protein YP_001314974.1 PFAM: transposase IS66; KEGG: ret:RHE_PA00098 probable insertion sequence transposase protein, IS66 family YP_001314975.1 PFAM: IS66 Orf2 family protein; KEGG: ret:RHE_PA00099 putative insertion sequence transposase protein YP_001314976.1 PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL70041 putative insertion sequence protein YP_001314977.1 PFAM: autoinducer synthesis protein; KEGG: atc:AGR_pTi_91 autoinducer synthesis protein TraI YP_001314978.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: rle:pRL70001 putative replication protein A YP_001314979.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; RepB plasmid partition; KEGG: rle:pRL70002 putative replication protein B YP_001314980.1 PFAM: replication protein C; KEGG: rle:pRL70003 putative replication protein YP_001314981.1 KEGG: eli:ELI_14595 hypothetical protein YP_001314982.1 KEGG: sme:SMa2259 hypothetical protein YP_001314984.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: nha:Nham_4513 prevent-host-death protein YP_001314985.1 PFAM: PilT protein domain protein; KEGG: mpt:Mpe_A3783 hypothetical protein YP_001314986.1 PFAM: restriction endonuclease; KEGG: son:SO0304 hypothetical endonuclease YP_001314987.1 SMART: TIR protein; KEGG: hne:HNE_0284 hypothetical protein YP_001314988.1 KEGG: rpd:RPD_3631 conserved hypothetical protein, interruption-N YP_001314990.1 PFAM: Integrase catalytic region; KEGG: atc:AGR_L_547 hypothetical protein YP_001314991.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_L_545 hypothetical protein YP_001314992.1 KEGG: vei:Veis_3661 hypothetical protein YP_001314994.1 PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL70041 putative insertion sequence protein YP_001314995.1 PFAM: IS66 Orf2 family protein; KEGG: ret:RHE_PA00099 putative insertion sequence transposase protein YP_001314996.1 PFAM: transposase IS66; KEGG: ret:RHE_PA00098 probable insertion sequence transposase protein, IS66 family YP_001314997.1 KEGG: ret:RHE_PA00097 hypothetical protein YP_001314998.1 KEGG: atc:AGR_L_551 hypothetical protein YP_001314999.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: nha:Nham_3924 IstB-like ATP-binding protein YP_001315000.1 PFAM: Integrase catalytic region; KEGG: nha:Nham_3923 integrase, catalytic region YP_001315001.1 PFAM: purine or other phosphorylase family 1; response regulator receiver; KEGG: bch:Bcen2424_3737 response regulator receiver protein YP_001315002.1 PFAM: response regulator receiver; KEGG: nmu:Nmul_A0543 response regulator receiver domain protein (CheY-like) YP_001315003.1 KEGG: bch:Bcen2424_3739 hypothetical protein YP_001315004.1 PFAM: glycoside hydrolase family 24; KEGG: bqu:BQ11590 phage related lysozyme YP_001315006.1 PFAM: glycoside hydrolase family 25; KEGG: mlo:mll7449 similar to autolytic lysozyme YP_001325696.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001325697.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001325698.1 PFAM: DGPFAETKE family protein; KEGG: sme:SMc01151 conserved hypothetical protein YP_001325699.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01150 putative RNA polymerase sigma-70 factor, ECF subfamily YP_001325700.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMc01149 hypothetical protein YP_001325701.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01148 PhnB protein YP_001325702.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001325703.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001325704.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01145 hypothetical protein YP_001325705.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001325706.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001325707.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001325708.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sme:SMc01141 probable nitrogen regulatory IIA protein YP_001325709.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: sme:SMc01140 probable sigma54 modulation protein YP_001325710.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001325711.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01138 probable ABC transporter ATP-binding protein YP_001325712.1 PFAM: OstA family protein; KEGG: sme:SMc01137 hypothetical transmembrane protein YP_001325713.1 PFAM: protein of unknown function DUF1239; KEGG: sme:SMc01136 hypothetical protein YP_001325715.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: sme:SMc01135 putative protease IV transmembrane protein YP_001325716.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001325717.1 KEGG: sme:SMc01133 hypothetical protein YP_001325718.1 PFAM: carbon monoxide dehydrogenase subunit G; KEGG: sme:SMc01132 hypothetical protein YP_001325719.1 KEGG: sme:SMc01131 hypothetical protein YP_001325720.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sme:SMc01130 putative tRNA/rRNA methyltransferase protein YP_001325721.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001325722.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc01128 putative sensor histidine kinase transmembrane protein YP_001325723.1 KEGG: sme:SMc01127 hypothetical protein YP_001325724.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001325725.1 This protein performs the mismatch recognition step during the DNA repair process YP_001325726.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001325727.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: sme:SMc01123 putative virulence factor MVIN homolog transmembrane protein YP_001325728.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01122 hypothetical protein YP_001325729.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001325730.1 PFAM: UspA domain protein; KEGG: sme:SMc01120 hypothetical protein YP_001325731.1 PFAM: nitrogen-fixing NifU domain protein; Scaffold protein Nfu/NifU; KEGG: sme:SMc01119 hypothetical protein YP_001325732.1 PFAM: peptidase M22 glycoprotease; KEGG: sme:SMc01118 hypothetical protein YP_001325733.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01117 putative acetyltransferase protein YP_001325734.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc01116 putative acyltransferase transmembrane protein YP_001325735.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001325736.1 PFAM: PhoH family protein; KEGG: sme:SMc01114 hypothetical PHOH-like protein YP_001325737.1 PFAM: protein of unknown function UPF0054; KEGG: sme:SMc01113 conserved hypothetical protein YP_001325738.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: sme:SMc01112 hypothetical protein YP_001325739.1 Transfers the fatty acyl group on membrane lipoproteins YP_001325740.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMc01110 DNA-binding protein YP_001325741.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001325742.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001325743.1 PFAM: protein of unknown function DUF1150; KEGG: sme:SMc01107 hypothetical protein YP_001325744.1 PFAM: heat shock protein Hsp20; KEGG: sme:SMc01106 probable small heat shock protein YP_001325745.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: sme:SMc01105 putative nucleoside hydrolase protein YP_001325746.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: sme:SMc01104 probable chemoreceptor (methyl-accepting chemotaxis) transmembrane protein YP_001325747.1 PFAM: PfkB domain protein; KEGG: sme:SMc01103 probable ribokinase protein YP_001325748.1 PFAM: protein of unknown function DUF195; KEGG: sme:SMc01102 hypothetical protein YP_001325749.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001325750.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001325751.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001325752.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sme:SMb20776 putative adenylate cyclase protein YP_001325753.1 PFAM: TonB-dependent receptor; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMb20775 hypothetical exported protein, TonB-dependent receptor protein YP_001325754.1 KEGG: sme:SMb20774 hypothetical membrane protein YP_001325755.1 KEGG: sme:SMc01097 hypothetical/unknown transmembrane protein YP_001325756.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001325757.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sme:SMc01095 probable multidrug-efflux system transmembrane protein YP_001325758.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc01094 putative multidrug efflux system transmembrane protein YP_001325759.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: sme:SMc01093 putative esterase protein YP_001325760.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01092 putative transcription regulator protein YP_001325761.1 KEGG: sme:SMc01091 hypothetical protein YP_001325762.1 PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc01090 putative ATP-dependent RNA helicase protein YP_001325763.1 PFAM: protein of unknown function DUF805; KEGG: sme:SMc01089 hypothetical protein YP_001325764.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001325765.1 PFAM: conserved hypothetical protein 730; KEGG: sme:SMc01731 hypothetical protein YP_001325766.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; pyrimidine 5'-nucleotidase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc01730 hypothetical protein YP_001325767.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc01729 hypothetical protein YP_001325768.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Ada metal-binding domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMc01728 putative transcription regulator protein YP_001325769.1 KEGG: sme:SMc01727 hypothetical protein YP_001325770.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001325771.1 KEGG: sme:SMc01725 hypothetical protein YP_001325772.1 PFAM: membrane protein of uknown function UCP014873; KEGG: sme:SMc01723 hypothetical protein YP_001325773.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001325774.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001325775.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001325776.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001325777.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sme:SMc01719 probable chemoreceptor (methyl-accepting chemotaxis) transmembrane protein YP_001325778.1 PFAM: SNARE associated Golgi protein; KEGG: sme:SMc01718 hypothetical protein YP_001325779.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sme:SMc01717 putative mercuric reductase protein YP_001325780.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc01716 putative sensor histidine kinase transmembrane protein YP_001325781.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: sme:SMc01708 hypothetical protein YP_001325782.1 PFAM: Invasion associated locus B family protein; KEGG: sme:SMc01707 conserved hypothetical signal peptide protein YP_001325783.1 KEGG: sme:SMc01706 conserved hypothetical signal peptide protein YP_001325784.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sme:SMc01705 hypothetical protein YP_001325785.1 PFAM: Protein of unknown function DUF1810; KEGG: sme:SMc01703 hypothetical protein YP_001325786.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: sme:SMc01701 hypothetical protein YP_001325787.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain YP_001325788.1 PFAM: protein of unknown function UPF0153; KEGG: sme:SMc02180 hypothetical protein YP_001325789.1 PFAM: metallophosphoesterase; KEGG: sme:SMc02179 hypothetical protein YP_001325790.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sme:SMc02178 hypothetical protein YP_001325791.1 KEGG: sme:SMc02177 hypothetical protein YP_001325792.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sme:SMc02176 putative adenylate cyclase transmembrane protein YP_001325793.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: sme:SMc02175 putative transcription regulator protein YP_001325794.1 PFAM: DoxX family protein; KEGG: sme:SMc02174 hypothetical protein YP_001325795.1 PFAM: RbsD or FucU transport; KEGG: sme:SMc02173 fucose operon fucU protein YP_001325796.1 PFAM: ROK family protein; KEGG: sme:SMc02172 putative transcription regulator protein YP_001325797.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMc02171 putative periplasmic binding ABC transporter protein YP_001325798.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02170 putative permease ABC transporter protein YP_001325799.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02169 putative ATP-binding ABC transporter protein YP_001325800.1 KEGG: sme:SMc02167 hypothetical protein YP_001325801.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001325802.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001325803.1 PFAM: PfkB domain protein; KEGG: sme:SMc02164 probable fructokinase protein YP_001325804.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001325805.1 activates fatty acids by binding to coenzyme A YP_001325806.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMc02160 putative permease transmembrane transport protein YP_001325807.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc02159 hypothetical protein YP_001325808.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc02158 putative acyltransferase protein YP_001325809.1 PFAM: phosphatidate cytidylyltransferase; KEGG: sme:SMc02157 hypothetical protein YP_001325810.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: sme:SMc02150 hypothetical protein YP_001325811.1 KEGG: sme:SMc02149 hypothetical protein YP_001325812.1 PFAM: protein of unknown function DUF344; KEGG: sme:SMc02148 hypothetical protein YP_001325813.1 TIGRFAM: Phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: sme:SMc02147 probable phosphate regulon sensor histidine kinase transmembrane protein YP_001325814.1 KEGG: sme:SMc02146 putative phosphate-binding periplasmic protein YP_001325815.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_C_740 phosphate ABC transporter (permease) YP_001325816.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02143 putative phosphate transport system permease ABC transporter protein YP_001325817.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001325818.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: sme:SMc02141 probable phosphate transport system transcriptional regulator protein YP_001325819.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc02140 phosphate regulon transcriptional regulatory protein YP_001325820.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aminoglycoside acetyltransferase (6') type I YP_001325821.1 PFAM: GcrA cell cycle regulator; KEGG: sme:SMc02139 hypothetical protein YP_001325822.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001325823.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001325824.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001325825.1 protein associated with Co2+ and Mg2+ efflux YP_001325826.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001325827.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc02134 hypothetical protein YP_001325828.1 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis YP_001325829.1 Catalyzes the deamination of dCTP to form dUTP YP_001325830.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMc02219 putative amino acid-binding periplasmic protein YP_001325831.1 KEGG: sme:SMc02220 hypothetical protein YP_001325832.1 KEGG: sme:SMc02221 hypothetical protein YP_001325833.1 KEGG: sme:SMc02222 hypothetical protein YP_001325834.1 PFAM: peptidase S24 S26A and S26B; KEGG: sme:SMc02223 putative transcription regulator protein YP_001325835.1 PFAM: sodium/calcium exchanger membrane region; KEGG: sme:SMc02224 putative calcium/proton antiporter transmembrane protein YP_001325836.1 PFAM: helix-turn-helix HxlR type; KEGG: sme:SMc02225 hypothetical protein YP_001325837.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMc02226 hypothetical protein YP_001325838.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: sme:SMc02227 putative fatty oxidation complex alpha subunit includes: enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, 3-hydroxybutyryl-CoA epimerase transmembrane protein YP_001325839.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001325840.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: sme:SMc02229 putative acyl-CoA dehydrogenase protein YP_001325841.1 PFAM: Peptidoglycan-binding domain 1 protein; Sel1 domain protein repeat-containing protein; KEGG: sme:SMc02230 hypothetical protein YP_001325842.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMc02232 hypothetical transmembrane protein YP_001325843.1 KEGG: sme:SMc02234 hypothetical protein YP_001325844.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMa0112 hypothetical protein YP_001325845.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc02235 putative transcription regulator protein YP_001325846.1 PFAM: metallophosphoesterase; KEGG: sme:SMc02236 hypothetical protein YP_001325847.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc02237 putative ATP-dependent helicase protein YP_001325848.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; Helix-turn-helix type 11 domain protein; KEGG: sme:SMc02238 hypothetical protein YP_001325849.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMc02239 hypothetical protein YP_001325850.1 PFAM: protein of unknown function DUF161; KEGG: sme:SMc02240 hypothetical protein YP_001325851.1 PFAM: Tetratricopeptide TPR_2 repeat protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc02241 hypothetical protein YP_001325852.1 KEGG: sme:SMc02242 hypothetical protein YP_001325853.1 PFAM: SCP-like extracellular; KEGG: sme:SMc02243 hypothetical protein YP_001325854.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sme:SMc02244 putative transmembrane protein YP_001325855.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001325856.1 PFAM: protein of unknown function DUF952; KEGG: sme:SMc02246 hypothetical protein YP_001325857.1 KEGG: sme:SMc02247 conserved hypothetical signal peptide protein YP_001325858.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc02248 putative transcription regulator protein YP_001325859.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein YP_001325860.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001325861.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001325862.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: sme:SMc02252 probable UDP-glucose 4-epimerase protein YP_001325863.1 TIGRFAM: chorismate mutase related enzymes; PFAM: Chorismate mutase; KEGG: sme:SMc02253 putative salicylate biosynthesis protein YP_001325864.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: sme:SMc02254 putative quinol oxidase subunit II transmembrane protein YP_001325865.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sme:SMc02255 putative quinol oxidase subunit I transmembrane protein YP_001325866.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sme:SMc02256 putative hippurate hydrolase protein YP_001325867.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02257 putative transport system permease ABC transporter protein YP_001325868.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02258 putative transport system permease ABC transporter protein YP_001325869.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMc02259 putative periplasmic binding ABC transporter protein YP_001325870.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02260 putative ATP-binding ABC transporter protein YP_001325871.1 PFAM: regulatory protein TetR; KEGG: sme:SMc02261 putative transcription regulator protein YP_001325872.1 PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sme:SMc02262 putative aminotransferase protein YP_001325873.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sme:SMc02263 acetolactate synthase large subunit YP_001325874.1 KEGG: sme:SMc02264 hypothetical protein YP_001325875.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001325876.1 KEGG: sme:SMc02266 hypothetical protein YP_001325877.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_3677 ABC sugar transporter, ATPase subunit YP_001325878.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rsp:RSP_3676 transcriptional regulator, GntR family YP_001325879.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: rsp:RSP_3675 esterase/lipase/thioesterase YP_001325880.1 PFAM: extracellular solute-binding protein family 1; KEGG: rsp:RSP_3674 ABC sugar transporter, periplasmic binding protein YP_001325881.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3673 ABC sugar transporter, inner membrane subunit YP_001325882.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3672 ABC sugar transporter, inner membrane subunit YP_001325883.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rsp:RSP_3671 putative D-tagatose 3-epimerase YP_001325884.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: rsp:RSP_3670 putative oxidoreductase myo-inositol 2-dehydrogenase YP_001325885.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: sme:SMc02267 hypothetical protein YP_001325886.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: sme:SMc02268 putative capsule expression protein YP_001325887.1 PFAM: Capsule polysaccharide biosynthesis protein; KEGG: sme:SMc02269 capsular polysaccharide biosynthesis/export protein YP_001325888.1 PFAM: sulfatase; KEGG: sme:SMc02270 capsular polysaccharide biosynthesis/export transmembrane protein YP_001325889.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02271 ribitol type dehydrogenase protein YP_001325890.1 PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sme:SMc02272 acyl-transferase transferase protein YP_001325891.1 PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase ; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein YP_001325892.1 PFAM: polysaccharide export protein; KEGG: sme:SMc02274 capsule polysaccharide exporter protein YP_001325893.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMc02275 probable pyrazinamidase/nicotinamidase (includes: pyrazinamidase, nicotinamidase) protein YP_001325894.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001325895.1 KEGG: sme:SMc02277 hypothetical unknown protein YP_001325896.1 KEGG: sme:SMc02278 hypothetical unknown transmembrane protein YP_001325897.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sme:SMa1905 putative MrcB penicillin binding protein B YP_001325899.1 KEGG: sme:SMc02304 hypothetical protein YP_001325900.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001325901.1 KEGG: sme:SMc02306 hypothetical protein YP_001325902.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001325903.1 PFAM: uncharacterised conserved protein UCP032146; KEGG: sme:SMc02308 hypothetical protein YP_001325904.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sme:SMc02309 putative arsenate reductase protein YP_001325905.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001325906.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001325907.1 PFAM: protein of unknown function DUF329; KEGG: sme:SMc02312 zinc-binding protein YP_001325908.1 KEGG: rso:RSc0974 probable transmembrane protein YP_001325909.1 KEGG: sme:SMc02314 hypothetical protein YP_001325910.1 KEGG: sme:SMc02315 hypothetical unknown protein YP_001325911.1 KEGG: sme:SMc02316 hypothetical protein YP_001325912.1 PFAM: protein of unknown function DUF930; KEGG: sme:SMc02317 hypothetical signal peptide protein YP_001325913.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sme:SMc02318 hypothetical protein YP_001325914.1 KEGG: sme:SMc02319 hypothetical unknown protein YP_001325915.1 PFAM: Transglycosylase-associated protein; KEGG: sme:SMc02320 hypothetical protein YP_001325916.1 TIGRFAM: L-rhamnose catabolism isomerase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc02321 putative sugar isomerase protein YP_001325917.1 TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: class II aldolase/adducin family protein; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02322 short chain dehydrogenase YP_001325918.1 PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: sme:SMc02323 putative transcription regulator protein YP_001325919.1 TIGRFAM: rhamnose ABC transporter, periplasmic rhamnose-binding protein; KEGG: sme:SMc02324 putative periplasmic binding ABC transporter protein YP_001325920.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02325 putative ATP-binding ABC transporter protein YP_001325921.1 PFAM: inner-membrane translocator; KEGG: sme:SMc03000 putative permease ABC transporter protein YP_001325922.1 PFAM: inner-membrane translocator; KEGG: sme:SMc03001 putative permease ABC transporter protein YP_001325923.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: sme:SMc03002 conserved hypothetical protein YP_001325924.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc03003 hypothetical protein YP_001325926.1 PFAM: chemotaxis sensory transducer; KEGG: sme:SMc03004 putative chemoreceptor (methyl-accepting chemotaxis protein) YP_001325927.1 KEGG: sme:SMc03005 putative chemotaxis protein CheX YP_001325928.1 PFAM: response regulator receiver; KEGG: sme:SMc03006 chemotaxis regulator protein YP_001325929.1 PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: sme:SMc03007 chemotaxis protein (sensory transduction histidine kinase) YP_001325930.1 PFAM: CheW domain protein; KEGG: sme:SMc03008 chemotaxis protein YP_001325931.1 PFAM: MCP methyltransferase CheR-type; KEGG: sme:SMc03009 chemotaxis protein methyltransferase YP_001325932.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001325933.1 PFAM: response regulator receiver; KEGG: sme:SMc03011 chemotaxis regulator protein YP_001325934.1 stimulates methylation of MCP proteins; catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_001325935.1 KEGG: sme:SMc03013 hypothetical protein YP_001325936.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001325937.1 PFAM: regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; KEGG: sme:SMc03015 putative transcription regulator protein YP_001325938.1 PFAM: regulatory protein LuxR; KEGG: sme:SMc03016 putative transcription regulator protein YP_001325939.1 KEGG: sme:SMc03017 hypothetical protein YP_001325940.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001325941.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001325942.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: sme:SMc03020 flagellar motor switch protein YP_001325943.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: sme:SMc03021 flagellar motor switch transmembrane protein YP_001325944.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001325945.1 PFAM: protein of unknown function DUF1217; KEGG: sme:SMc03023 hypothetical protein YP_001325946.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001325947.1 involved in type III protein export during flagellum assembly YP_001325948.1 KEGG: sme:SMc03026 hypothetical protein YP_001325949.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella YP_001325950.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001325951.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001325952.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella YP_001325953.1 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella YP_001325954.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001325955.1 KEGG: sme:SMc03033 hypothetical protein YP_001325956.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001325957.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sme:SMc03035 flagellar transmembrane protein YP_001325958.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001325959.1 PFAM: flagellin domain protein; KEGG: sme:SMc03037 flagellin A protein YP_001325960.1 PFAM: flagellin domain protein; KEGG: sme:SMc03038 flagellin B protein YP_001325961.1 PFAM: flagellin domain protein; KEGG: sme:SMc03039 probable flagellin D protein YP_001325962.1 PFAM: flagellin domain protein; KEGG: sme:SMc03040 flagellin protein YP_001325964.1 KEGG: sme:SMc03041 hypothetical protein YP_001325965.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001325966.1 a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation YP_001325967.1 KEGG: sme:SMc03044 chemotaxis protein (motility protein D) YP_001325968.1 PFAM: Lytic transglycosylase catalytic; KEGG: sme:SMc03045 hypothetical protein YP_001325969.1 PFAM: transcriptional regulator domain protein; KEGG: sme:SMc03046 putative transcription regulator protein YP_001325970.1 the hook connects flagellar basal body to the flagellar filament YP_001325971.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001325972.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella YP_001325973.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001325974.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001325975.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001325976.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum YP_001325977.1 membrane protein involved in the flagellar export apparatus YP_001325978.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001325979.1 KEGG: sme:SMc03056 hypothetical protein YP_001325980.1 KEGG: sme:SMc03071 hypothetical protein YP_001325981.1 KEGG: sme:SMc03072 hypothetical protein YP_001325982.1 KEGG: sme:SMc03057 hypothetical protein YP_001325983.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMc03058 putative glycosyltransferase protein YP_001325984.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001325985.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMc03060 putative transcription regulator protein YP_001325986.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc03061 alpha-glucosides-binding periplasmic ABC transporter protein YP_001325987.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03062 alpha-glucosides transport system permease ABC transporter protein YP_001325988.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03063 alpha-glucosides transport system permease ABC transporter protein YP_001325989.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMc03064 probable alpha-glucosidase protein YP_001325990.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc03065 alpha-glucosides transport ATP-binding ABC transporter protein YP_001325991.1 KEGG: sme:SMc03066 hypothetical unknown protein YP_001325992.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001325993.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: sme:SMc03069 6-phosphogluconolactonase protein YP_001325994.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001325995.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc00761 putative oxidoreductase protein YP_001325996.1 PFAM: glutamine synthetase catalytic region; KEGG: sme:SMc00762 putative glutamine synthetase protein YP_001325997.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc00763 hypothetical protein YP_001325998.1 KEGG: sme:SMc00764 hypothetical/unknown transmembrane protein YP_001325999.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sme:SMc00765 probable methyl-accepting chemotaxis protein YP_001326000.1 PFAM: regulatory protein LysR; KEGG: sme:SMc00766 putative transcription regulator protein YP_001326001.1 KEGG: sme:SMc00767 hypothetical protein YP_001326002.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sme:SMc00768 isocitrate lyase YP_001326003.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: sme:SMc00769 hypothetical protein YP_001326004.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc00770 probable putrescine-binding periplasmic protein YP_001326005.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc00771 probable putrescine transport ATP-binding protein YP_001326006.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00772 probable putrescine transport system permease protein YP_001326007.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00773 probable putrescine transport system permease protein YP_001326008.1 PFAM: AsmA family protein; KEGG: sme:SMc00838 hypothetical protein YP_001326009.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_001326010.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00775 putative iron(III) permease protein YP_001326011.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc00776 putative sensor histidine kinase protein YP_001326012.1 TIGRFAM: phasin; KEGG: sme:SMc00777 hypothetical protein YP_001326013.1 PFAM: regulatory protein LuxR; KEGG: pde:Pden_3582 response regulator receiver protein YP_001326014.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00778 putative oxidoreductase protein YP_001326015.1 TIGRFAM: FAD-linked oxidoreductase; PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00779 putative FAD-dependent oxidoreductase protein YP_001326016.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00780 putative transcription regulator protein YP_001326017.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sme:SMc00781 putative malonic semialdehyde oxidative decarboxylase protein YP_001326018.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: sme:SMc00782 hypothetical protein YP_001326019.1 PFAM: peptidase M48 Ste24p; KEGG: sme:SMc00783 hypothetical protein YP_001326020.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc00784 putative iron binding protein YP_001326021.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons YP_001326022.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc00786 probable periplasmic dipeptide-binding protein YP_001326023.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00787 probable dipeptide transport system permease protein YP_001326024.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00788 probable dipeptide transport system permease protein YP_001326025.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00789 probable dipeptide transport ATP-binding ABC transporter protein YP_001326026.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc00790 probable dipeptide transport ATP-binding ABC transporter protein YP_001326027.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMc00791 hypothetical protein YP_001326028.1 KEGG: sme:SMc00792 hypothetical protein YP_001326029.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMc00793 putative permease protein YP_001326030.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_001326032.1 PFAM: 17 kDa surface antigen; KEGG: sme:SMc00795 hypothetical protein YP_001326034.1 PFAM: protein of unknown function DUF1328; KEGG: sme:SMc00796 hypothetical protein YP_001326035.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc00797 putative oxidoreductase protein YP_001326036.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rxy:Rxyl_2603 twin-arginine translocation pathway signal YP_001326037.1 PFAM: inner-membrane translocator; KEGG: msm:MSMEG_1373 ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_001326038.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rxy:Rxyl_2601 ABC transporter related YP_001326039.1 TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: rha:RHA1_ro08464 probable acetylornithine deacetylase YP_001326040.1 KEGG: sme:SMc00798 hypothetical protein YP_001326041.1 PFAM: MgtC/SapB transporter; KEGG: sme:SMc00799 hypothetical transmembrane protein YP_001326042.1 KEGG: sme:SMc00800 hypothetical protein YP_001326043.1 KEGG: sme:SMc00801 hypothetical protein YP_001326044.1 KEGG: sme:SMc00802 hypothetical protein YP_001326045.1 KEGG: rle:RL3128 putative transmembrane protein YP_001326046.1 PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: sme:SMc00803 hypothetical protein YP_001326047.1 KEGG: sme:SMc00804 hypothetical protein YP_001326048.1 KEGG: sme:SMc00805 hypothetical protein YP_001326049.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMc00806 hypothetical protein YP_001326050.1 KEGG: rpd:RPD_2550 hypothetical protein YP_001326051.1 KEGG: saz:Sama_3338 conserved hypothetical protein YP_001326052.1 PFAM: regulatory protein TetR; KEGG: gvi:gll0188 TetR family transcriptional regulatory protein YP_001326053.1 PFAM: Uncharacterized protein UPF0065; KEGG: pde:Pden_3075 uncharacterized protein UPF0065 YP_001326054.1 KEGG: pde:Pden_3074 putative tricarboxylic transport membrane protein YP_001326055.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: pde:Pden_3073 protein of unknown function DUF112, transmembrane YP_001326056.1 PFAM: GntR domain protein; KEGG: pde:Pden_3072 transcriptional regulator, GntR family YP_001326057.1 catalyzes the conversion of citrate to isocitrate YP_001326058.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1632 putative LysR-family transcriptional regulator YP_001326059.1 KEGG: sme:SMa1630 hypothetical protein YP_001326060.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: sme:SMa1629 short chain dehydrogenase YP_001326061.1 PFAM: regulatory protein MarR; KEGG: rle:pRL120291 putative MarR family transcriptional regulator YP_001326062.1 KEGG: rle:pRL120290 hypothetical protein YP_001326063.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rle:pRL120289 putative choline dehydrogenase YP_001326064.1 PFAM: Ppx/GppA phosphatase; KEGG: sme:SMc00810 exopolyphosphatase YP_001326065.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: sme:SMc00811 probable cell division protein YP_001326066.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc00812 hypothetical protein YP_001326067.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001326068.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: rbe:RBE_1274 transposase and inactivated derivative YP_001326069.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00813 putative transport transmembrane protein YP_001326070.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc00814 hypothetical signal peptide protein YP_001326071.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001326072.1 PFAM: protein of unknown function DUF1123; KEGG: sme:SMc00816 hypothetical protein YP_001326073.1 PFAM: dienelactone hydrolase; KEGG: sme:SMc00817 putative carboxymethylenebutenolidase (dienelactone hydrolase) protein YP_001326074.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00818 putative hydrogen peroxide-inducible genes activator (morphology and auto-aggregation control protein). YP_001326075.1 PFAM: Catalase domain protein; KEGG: sme:SMc00819 catalase hydroperoxidase HPII(III) protein YP_001326076.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00820 putative transcriptional regulator protein YP_001326077.1 KEGG: sme:SMc00821 hypothetical protein YP_001326078.1 KEGG: sme:SMc00824 hypothetical protein YP_001326079.1 TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GCS2; KEGG: sme:SMc00825 putative glutamate--cysteine ligase precursor protein YP_001326080.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001326081.1 PFAM: phosphate transporter; KEGG: sme:SMc00827 putative transport transmembrane protein YP_001326082.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc00828 hypothetical protein YP_001326083.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc00829 putative transcription regulator protein YP_001326084.1 KEGG: sme:SMc00830 hypothetical protein YP_001326085.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00831 hypothetical transcription regulator protein YP_001326086.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00832 probable glycolate oxidase subunit protein YP_001326087.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00833 probable glycolate oxidase subunit protein YP_001326088.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: sme:SMc00926 probable glycolate oxidase iron-sulfur subunit protein YP_001326089.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc00925 putative signal peptide protein YP_001326090.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc00924 hypothetical protein YP_001326091.1 PFAM: methyladenine glycosylase; KEGG: sme:SMc00923 probable DNA-3-methyladenine glycosylase I protein YP_001326092.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sme:SMc00922 putative transporter transmembrane protein YP_001326093.1 PFAM: protein of unknown function DUF305; KEGG: sme:SMc00921 hypothetical signal peptide protein YP_001326094.1 KEGG: sme:SMc00931 hypothetical/unknown protein YP_001326095.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001326096.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001326097.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001326098.1 PFAM: Glutathione S-transferase domain; KEGG: rle:RL0881 putative glutathione S-transferase YP_001326099.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc00914 putative oxidoreductase protein YP_001326100.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001326101.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001326102.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc00910 hypothetical protein YP_001326103.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001326104.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme YP_001326105.1 KEGG: sme:SMc00907 hypothetical protein YP_001326106.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00906 putative acetyltransferase protein YP_001326107.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sme:SMc00905 putative deaminase protein YP_001326108.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sme:SMc00904 ribosomal large subunit pseudouridine synthase B YP_001326109.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: sme:SMc00902 hypothetical protein YP_001326110.1 PFAM: Patatin; KEGG: sme:SMc00930 hypothetical transmembrane protein YP_001326111.1 PFAM: porin; KEGG: mlo:mlr0810 outer membrane protein YP_001326112.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: sme:SMc00898 probable glutathione-regulated potassium-efflux system transmembrane protein YP_001326113.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sme:SMc00897 PmbA protein YP_001326114.1 PFAM: inositol monophosphatase; KEGG: sme:SMc00896 putative sulfite biosynthesis protein YP_001326115.1 KEGG: sme:SMc00895 hypothetical protein YP_001326116.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001326117.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc00893 putative phosphoglycolate phosphatase YP_001326118.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001326119.1 KEGG: sme:SMc00933 hypothetical protein YP_001326120.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001326121.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc00888 putative contains A 2-component receiver domain protein YP_001326122.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: sme:SMc00887 hypothetical protein YP_001326123.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00929 putative transcription regulator protein YP_001326124.1 PFAM: trimethylamine methyltransferase; KEGG: sme:SMc00886 hypothetical protein YP_001326125.1 PFAM: PRC-barrel domain protein; KEGG: sme:SMc00885 hypothetical transmembrane signal peptide protein YP_001326126.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001326127.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sme:SMc00883 hypothetical protein YP_001326128.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001326129.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: sme:SMc00881 putative 2-dehydro-3-deoxygalactonokinase protein YP_001326130.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00880 probable oxidoreductase protein YP_001326131.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMc00879 putative transcription regulator protein YP_001326132.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: sme:SMc00878 putative transcription regulator protein YP_001326133.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: sme:SMc00877 putative transcription regulator protein YP_001326134.1 PFAM: protein of unknown function DUF59; KEGG: sme:SMc00876 putative MRP protein homolog ATP-binding YP_001326135.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: sme:SMc00874 probable magnesium and cobalt transport transmembrane protein YP_001326136.1 PFAM: K potassium transporter; KEGG: sme:SMc00873 probable KUP system potassium uptake transmembrane protein YP_001326137.1 PFAM: cell wall hydrolase SleB; KEGG: sme:SMc00928 hypothetical signal peptide protein YP_001326138.1 KEGG: sme:SMc00872 putative FOF1 ATP synthase, subunit I transmembrane protein YP_001326139.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001326140.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001326141.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_001326142.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001326143.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001326144.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sme:SMc00866 hypothetical protein YP_001326145.1 KEGG: sme:SMc00865 hypothetical protein YP_001326146.1 KEGG: sme:SMc00864 hypothetical/unknown protein YP_001326147.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: sme:SMc00863 probable molybdenum cofactor biosynthesis protein B YP_001326148.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001326149.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc00861 hypothetical signal peptide protein YP_001326150.1 PFAM: Polyprenyl synthetase; KEGG: sme:SMc00860 putative octaprenyl-diphosphate synthase protein YP_001326151.1 KEGG: sme:SMc00859 hypothetical/unknown protein YP_001326152.1 PFAM: methyltransferase small; KEGG: sme:SMc00858 hypothetical protein YP_001326153.1 PFAM: peptidase S49; KEGG: sme:SMc00857 putative protease protein YP_001326154.1 KEGG: sme:SMc00856 hypothetical protein YP_001326155.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001326156.1 PFAM: LemA family protein; KEGG: sme:SMc00853 hypothetical transmembrane protein YP_001326157.1 KEGG: sme:SMc00852 hypothetical transmembrane signal peptide protein YP_001326158.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001326159.1 PFAM: protein of unknown function DUF523; KEGG: sme:SMc00850 hypothetical protein YP_001326160.1 KEGG: vei:Veis_3475 plasmid stability protein StbC YP_001326161.1 PFAM: PilT protein domain protein; KEGG: vei:Veis_3474 PilT protein domain protein YP_001326162.1 KEGG: sme:SMc00849 hypothetical protein YP_001326163.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001326164.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: sme:SMc00992 hypothetical protein YP_001326165.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc00991 putative putrescine-binding periplasmic protein YP_001326166.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00990 putative fosmidomycin resistance antibiotic resistance transmembrane protein YP_001326167.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: sme:SMc00994 putative transcription regulator protein YP_001326168.1 PFAM: MltA-interacting MipA family protein; KEGG: sme:SMc00989 hypothetical signal peptide protein YP_001326169.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001326170.1 KEGG: sme:SMc00987 hypothetical protein YP_001326171.1 PFAM: protein of unknown function DUF1217; KEGG: sme:SMc00986 hypothetical protein YP_001326172.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00985 putative oxidoreductase protein YP_001326173.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC domain; KEGG: sme:SMc00984 putative translation factor YP_001326174.1 KEGG: sme:SMc00983 hypothetical/unknown protein YP_001326175.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMc00982 putative dioxygenase protein YP_001326176.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMc00981 putative ferredoxin protein YP_001326177.1 PFAM: glycoside hydrolase family 25; KEGG: sme:SMc00980 hypothetical protein YP_001326178.1 PFAM: BA14K family protein; KEGG: sme:SMc00979 hypothetical protein YP_001326179.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMc00977 putative acyl-CoA dehydrogenase protein YP_001326180.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001326181.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: sme:SMc00975 probable chemoreceptor (methyl-accepting chemotaxis) transmembrane protein YP_001326182.1 PFAM: (Uracil-5)-methyltransferase; KEGG: sme:SMc00974 putative RNA methyltransferase protein YP_001326183.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: sme:SMc00973 putative hemolysin YP_001326184.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001326185.1 PFAM: Pirin domain protein; KEGG: sme:SMc00971 hypothetical protein YP_001326186.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001326187.1 PFAM: histone deacetylase superfamily; KEGG: sme:SMc00969 hypothetical protein YP_001326188.1 PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00968 putative oxidoreductase protein YP_001326189.1 PFAM: thioesterase superfamily protein; KEGG: sme:SMc00967 hypothetical protein YP_001326190.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: sme:SMc00966 putative acetyl-CoA acyltransferase protein YP_001326191.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00965 hypothetical protein YP_001326192.1 PFAM: BioY protein; KEGG: sme:SMc00964 hypothetical transmembrane protein YP_001326193.1 PFAM: cobalt transport protein; KEGG: sme:SMc00963 hypothetical transmembrane protein YP_001326194.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00962 putative ATP-binding ABC transporter protein YP_001326195.1 PFAM: protein of unknown function DUF1006; KEGG: sme:SMc00961 hypothetical protein YP_001326196.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sme:SMc00960 TldD protein YP_001326197.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; KEGG: sme:SMc00068 hypothetical protein YP_001326198.1 PFAM: polysaccharide deacetylase; KEGG: sme:SMc00001 hypothetical protein YP_001326199.1 KEGG: eba:ebA2590 hypothetical protein YP_001326200.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001326201.1 KEGG: sme:SMc00002 hypothetical protein YP_001326202.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: sme:SMc00003 putative chaperone protein YP_001326203.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001326204.1 PFAM: Phosphoglycerate mutase; KEGG: sme:SMc00006 hypothetical protein YP_001326205.1 PFAM: protein of unknown function DUF1344; KEGG: sme:SMc00070 conserved hypothetical signal peptide protein YP_001326206.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001326207.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: sme:SMc00008 probable riboflavin biosynthesis protein RIBA includes: GTP cyclohydrolase II 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001326208.1 PFAM: Invasion associated locus B family protein; KEGG: sme:SMc00071 hypothetical protein YP_001326209.1 TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome C oxidase subunit II transmembrane region; KEGG: sme:SMc00009 cytochrome c oxidase subunit II YP_001326210.1 TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I; KEGG: sme:SMc00010 cytochrome c oxidase subunit I YP_001326211.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001326212.1 KEGG: sme:SMc00130 hypothetical protein YP_001326213.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001326214.1 PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc00013 cytochrome c oxidase subunit III YP_001326215.1 KEGG: mlo:mlr7497 hypothetical protein YP_001326216.1 PFAM: protein of unknown function DUF983; KEGG: sme:SMc00014 hypothetical/unknown transmembrane protein YP_001326217.1 PFAM: Surfeit locus 1 family protein; KEGG: sme:SMc00085 putative cytochrome oxidase complex biogenesis factor transmembrane protein YP_001326218.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001326219.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001326220.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001326221.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMc00072 hypothetical peroxiredoxin protein YP_001326222.1 KEGG: sme:SMc00073 hypothetical protein YP_001326223.1 PFAM: protein of unknown function DUF179; KEGG: sme:SMc00019 putative transcriptional regulator YP_001326224.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; KEGG: sme:SMc00074 hypothetical transmembrane signal peptide protein YP_001326225.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00075 probable ribosomal-protein-alanine acetyltransferase YP_001326226.1 PFAM: peptidase M16 domain protein; KEGG: sme:SMc00451 putative processing protease protein YP_001326227.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001326228.1 KEGG: sme:SMc00020 hypothetical protein YP_001326229.1 PFAM: Extracellular ligand-binding receptor; KEGG: sme:SMc00078 probable LEU/ILE/VAL-binding protein YP_001326230.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc00079 hypothetical protein YP_001326231.1 PFAM: regulatory protein ArsR; Helix-turn-helix type 11 domain protein; KEGG: sme:SMc00080 hypothetical protein YP_001326232.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: sme:SMc00021 adenine DNA methyltransferase protein YP_001326233.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc00081 hypothetical protein YP_001326234.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sme:SMc00452 probable A/G-specific adenine glycosylase protein YP_001326235.1 PFAM: protein of unknown function DUF1159; KEGG: sme:SMc00022 hypothetical protein YP_001326236.1 PFAM: DSBA oxidoreductase; KEGG: sme:SMc00023 hypothetical protein YP_001326237.1 PFAM: protein of unknown function DUF559; KEGG: ret:RHE_CH01424 hypothetical protein YP_001326238.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein; KEGG: sme:SMc00024 putative chromosome partition protein YP_001326239.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001326240.1 KEGG: sme:SMc00083 hypothetical/unknown protein YP_001326241.1 KEGG: sme:SMc00084 hypothetical/unknown protein YP_001326242.1 KEGG: sme:SMc00026 hypothetical protein YP_001326243.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc00087 putative hydrolase protein YP_001326244.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMc00028 hypothetical protein YP_001326245.1 KEGG: sme:SMc00088 hypothetical/unknown transmembrane protein YP_001326246.1 KEGG: sme:SMc00029 hypothetical/unknown protein YP_001326247.1 SMART: helix-turn-helix domain protein; KEGG: sme:SMc00089 hypothetical protein YP_001326248.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001326249.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001326250.1 TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: sme:SMc00092 probable phosphoadenosine phosphosulfate reductase PAPS reductase, thioredoxin dependent padops reductase 3'-phosphoadenylylsulfate sulfotransferase cysteine biosynthesis protein YP_001326251.1 KEGG: sme:SMc00030 hypothetical/unknown signal peptide protein YP_001326252.1 KEGG: sme:SMc00031 hypothetical/unknown transmembrane protein YP_001326253.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001326254.1 catalyzes the formation of betaine from betaine aldehyde YP_001326255.1 PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein YP_001326256.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001326257.1 KEGG: sme:SMc00032 hypothetical protein YP_001326258.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: sme:SMc00033 hypothetical protein YP_001326259.1 TIGRFAM: Quinone oxidoreductase putative PIG3; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00034 putative oxidoreductase protein YP_001326260.1 KEGG: sme:SMc00096 hypothetical/unknown protein YP_001326261.1 PFAM: L-asparaginase II; KEGG: sme:SMc00035 hypothetical protein YP_001326262.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00036 putative glutathione S-transferase protein YP_001326263.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00037 putative transcription regulator protein YP_001326264.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00097 putative glutathione S-transferase protein YP_001326265.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: sme:SMc00038 hypothetical protein YP_001326266.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc00039 hypothetical protein YP_001326267.1 PFAM: regulatory protein MarR; transcriptional regulator TrmB; KEGG: sme:SMc00098 putative transcription regulator protein YP_001326268.1 PFAM: OsmC family protein; KEGG: sme:SMc00040 hypothetical protein YP_001326269.1 PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: sme:SMc00100 hypothetical protein YP_001326270.1 KEGG: sme:SMc00041 hypothetical protein YP_001326271.1 PFAM: aldo/keto reductase; KEGG: sme:SMc00101 putative oxidoreductase protein YP_001326272.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001326273.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc00103 putative alpha-halocarboxylic acid dehalogenase protein YP_001326274.1 KEGG: sme:SMc00104 hypothetical protein YP_001326275.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00105 putative oxidoreductase transmembrane protein YP_001326276.1 PFAM: aminotransferase class IV; KEGG: sme:SMc00042 branched-chain amino acid aminotransferase YP_001326277.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc00106 hypothetical protein YP_001326278.1 PFAM: manganese and iron superoxide dismutase; KEGG: sme:SMc00043 probable superoxide dismutase Fe protein YP_001326279.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: sme:SMc00107 putative transcription regulator protein YP_001326280.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc00044 putative amino acid efflux protein YP_001326281.1 PFAM: cytochrome c class II; KEGG: sme:SMc00045 putative cytochrome c signal peptide protein YP_001326282.1 KEGG: sme:SMc00086 putative diheme cytochrome c-type signal peptide protein YP_001326283.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00108 putative acetyltransferase protein YP_001326284.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sme:SMc00109 putative transcription regulator protein YP_001326285.1 PFAM: beta-lactamase; KEGG: sme:SMc00047 putative beta-lactamase signal peptide protein YP_001326286.1 PFAM: Pyrrolo-quinoline quinone; KEGG: sme:SMc00110 probable glucose dehydrogenase (pyrroloquinoline-quinone) protein YP_001326287.1 PFAM: protein of unknown function UPF0061; KEGG: sme:SMc00453 hypothetical protein YP_001326288.1 PFAM: homocysteine S-methyltransferase; KEGG: rle:RL1357 putative homocysteine S-methyltransferase YP_001326289.1 PFAM: protein of unknown function DUF1697; KEGG: rle:RL1359 hypothetical protein YP_001326290.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: sme:SMc00114 probable protease II oligopeptidase B hydrolase serine protease protein YP_001326291.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: xcb:XC_3052 transcriptional regulator YP_001326292.1 KEGG: pen:PSEEN1394 hypothetical protein YP_001326293.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc00115 hypothetical protein YP_001326294.1 PFAM: UspA domain protein; KEGG: sme:SMc00048 hypothetical protein YP_001326295.1 KEGG: sme:SMc00049 hypothetical protein YP_001326296.1 PFAM: Hly-III family protein; KEGG: sme:SMc00455 hypothetical transmembrane protein YP_001326297.1 KEGG: sme:SMc00116 hypothetical protein YP_001326298.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001326299.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_001326300.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001326301.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001326302.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001326303.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001326304.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001326305.1 PFAM: ROSMUCR transcriptional regulator; KEGG: sme:SMc00058 transcription regulator protein YP_001326306.1 PFAM: Fe-S metabolism associated SufE; KEGG: sme:SMc00118 conserved hypothetical protein YP_001326307.1 KEGG: sme:SMc00456 hypothetical protein YP_001326308.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc00059 putative sensor histidine kinase protein YP_001326309.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMc00060 hypothetical protein YP_001326310.1 PFAM: protein of unknown function DUF1491; KEGG: sme:SMc00061 hypothetical protein YP_001326311.1 KEGG: sme:SMc00120 hypothetical protein YP_001326312.1 PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: sme:SMc00062 hypothetical protein YP_001326313.1 KEGG: sme:SMc00063 hypothetical protein YP_001326315.1 KEGG: sme:SMc00128 hypothetical protein YP_001326316.1 PFAM: protein of unknown function DUF1214; KEGG: sme:SMc00457 hypothetical protein YP_001326317.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sme:SMc00122 putative penicillin-binding protein YP_001326318.1 PFAM: protein of unknown function UPF0153; KEGG: sme:SMc00064 hypothetical protein YP_001326319.1 KEGG: sme:SMc00123 hypothetical protein YP_001326320.1 KEGG: sme:SMc00065 conserved hypothetical signal peptide protein YP_001326321.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc00458 probable transcription regulator protein YP_001326322.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc00129 probable sensor histidine kinase protein YP_001326323.1 KEGG: sme:SMc00067 probable outer-membranne lipoprotein YP_001326324.1 KEGG: sme:SMc02361 cytochrome C-type biogenesis transmembrane protein YP_001326325.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001326326.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: sme:SMc02363 cytochrome C-type biogenesis transmembrane protein YP_001326327.1 PFAM: cytochrome C biogenesis protein; KEGG: sme:SMc02364 cytochrome C-type biogenesis transmembrane protein YP_001326328.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc02365 protease precursor protein YP_001326329.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc02366 putative transcription regulator protein YP_001326330.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc02367 putative sensor histidine kinase transmembrane protein YP_001326331.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001326332.1 KEGG: sme:SMc02369 putative sensor histidine kinase transmembrane protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001326333.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: sme:SMc02370 probable aminopeptidase N protein YP_001326334.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc02371 hypothetical protein YP_001326335.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc02372 putative transport transmembrane protein YP_001326336.1 KEGG: sme:SMc02373 hypothetical unknown protein YP_001326337.1 KEGG: sme:SMc02374 hypothetical unknown protein YP_001326338.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: sme:SMc02375 putative DNA polymerase bacteriophage-type YP_001326339.1 KEGG: sme:SMc02376 putative heat shock protein YP_001326340.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: sme:SMc02377 probable electron transfer flavoprotein-ubiquinone oxidoreductase YP_001326341.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02378 putative periplasmic binding transmembrane protein YP_001326342.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02379 putative permease protein YP_001326343.1 TIGRFAM: Alcohol dehydrogenase. zinc-binding type 1; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc02380 putative oxidoreductase transmembrane protein YP_001326344.1 PFAM: helix-turn-helix HxlR type; KEGG: sme:SMc02381 hypothetical protein YP_001326345.1 PFAM: diacylglycerol kinase catalytic region; KEGG: sme:SMc02382 hypothetical protein YP_001326346.1 PFAM: glycosyl transferase family 39; KEGG: sme:SMc02383 hypothetical protein YP_001326347.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMc02384 putative glycosyltransferase transmembrane protein YP_001326348.1 KEGG: sme:SMc02385 hypothetical protein YP_001326349.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001326350.1 PFAM: protein of unknown function UPF0060; KEGG: sme:SMc02387 hypothetical transmembrane protein YP_001326351.1 KEGG: sme:SMc02388 hypothetical unknown transmembrane protein YP_001326352.1 KEGG: sme:SMc02389 hypothetical unknown transmembrane protein YP_001326353.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc02390 putative glutathione S-transferase protein YP_001326354.1 KEGG: sme:SMc02391 hypothetical protein YP_001326355.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sme:SMc02392 hypothetical protein YP_001326356.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate YP_001326359.1 PFAM: porin; KEGG: sme:SMc02396 probable outer membrane protein YP_001326360.1 PFAM: phage integrase family protein; KEGG: sme:SMc02397 putative integrase protein YP_001326361.1 PFAM: porin; KEGG: sme:SMc02396 probable outer membrane protein YP_001326362.1 PFAM: BA14K family protein; KEGG: sme:SMc02401 hypothetical protein YP_001326363.1 PFAM: Lytic transglycosylase catalytic; KEGG: sme:SMc02403 putative murein transglycosylase protein YP_001326364.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001326365.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001326366.1 PFAM: protein of unknown function DUF88; KEGG: sme:SMc02407 hypothetical protein YP_001326367.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001326368.1 KEGG: sme:SMc02659 putative guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001326369.1 KEGG: sme:SMc02656 hypothetical unknown protein YP_001326370.1 KEGG: sme:SMc02655 hypothetical protein YP_001326371.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001326372.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; KEGG: sme:SMc02653 probable signal peptidase I transmembrane protein YP_001326373.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001326374.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001326375.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: sme:SMc02646 hypothetical protein YP_001326376.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc02645 putative cyclopropane-fatty-acyl-phospholipid synthase protein YP_001326377.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: sme:SMc02644 hypothetical protein YP_001326378.1 KEGG: sme:SMc02642 hypothetical signal peptide protein YP_001326379.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sme:SMc02641 UDP-glucose 6-dehydrogenase protein YP_001326380.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMc02640 UDP-glucuronic acid epimerase protein YP_001326381.1 PFAM: regulatory protein ArsR; KEGG: sme:SMc02639 putative transcription regulator protein YP_001326382.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMc02638 hypothetical protein YP_001326383.1 KEGG: sme:SMc02637 hypothetical protein YP_001326384.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001326385.1 PFAM: protein of unknown function DUF839; KEGG: sme:SMc02634 hypothetical transmembrane protein YP_001326386.1 KEGG: sme:SMc02633 hypothetical protein YP_001326387.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sme:SMc02632 hypothetical protein YP_001326388.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: sme:SMc02631 hypothetical protein YP_001326389.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc02603 putative transport transmembrane protein YP_001326390.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001326391.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001326392.1 TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; KEGG: sme:SMc02598 probable nicotinate-nucleotide pyrophosphorylase carboxylating protein YP_001326393.1 PFAM: superoxide dismutase copper/zinc binding; KEGG: sme:SMc02597 putative superoxide dismutase Cu-Zn precursor (bacteriocuprein) transmembrane protein YP_001326394.1 KEGG: sme:SMc02565 hypothetical protein YP_001326395.1 KEGG: sme:SMc02561 hypothetical protein YP_001326396.1 KEGG: sme:SMc02559 hypothetical protein YP_001326397.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc02558 hypothetical protein YP_001326398.1 KEGG: sme:SMc02557 hypothetical protein YP_001326399.1 KEGG: sme:SMc02556 hypothetical protein YP_001326400.1 KEGG: sme:SMc02555 conserved hypothetical signal peptide protein YP_001326401.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc02554 hypothetical protein YP_001326402.1 PFAM: protein of unknown function DUF159; KEGG: sme:SMc02553 hypothetical protein YP_001326403.1 KEGG: sme:SMc02552 hypothetical unknown protein YP_001326404.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001326405.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc02550 hypothetical protein YP_001326406.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc02549 hypothetical protein YP_001326407.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc02548 hypothetical protein YP_001326408.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc02547 putative proline iminopeptidase protein YP_001326409.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: sme:SMc02546 2-isopropylmalate synthase YP_001326410.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc02545 hypothetical transmembrane protein YP_001326411.1 PFAM: conserved hypothetical protein 730; KEGG: sme:SMc02544 hypothetical protein YP_001326412.1 PFAM: Peptidoglycan-binding LysM; KEGG: sme:SMc02543 hypothetical protein YP_001326413.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00550 probable ABC transporter ATP-binding transmembrane protein YP_001326414.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001326415.1 TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc00552 putative CDP-diacylglycerol--serine O-phosphatidyltransferase transmembrane protein YP_001326416.1 PFAM: transposase IS4 family protein; KEGG: nha:Nham_2758 transposase, IS4 YP_001326417.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00553 putative oxidoreductase protein YP_001326418.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001326419.1 PFAM: Colicin V production protein; KEGG: sme:SMc00555 putative colicin V production homolog transmembrane protein YP_001326420.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001326421.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; KEGG: sme:SMc00557 putative alanine racemase protein YP_001326422.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: sme:SMc00558 putative transcription regulator protein YP_001326423.1 PFAM: AzlC family protein; KEGG: sme:SMc00559 hypothetical protein YP_001326424.1 PFAM: branched-chain amino acid transport; KEGG: sme:SMc00560 hypothetical protein YP_001326425.1 unwinds double stranded DNA YP_001326426.1 PFAM: regulatory protein MarR; KEGG: sme:SMc00562 putative transcription regulator protein YP_001326427.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00563 putative transport protein transmembrane YP_001326428.1 PFAM: secretion protein HlyD family protein; KEGG: sme:SMc00564 putative transport protein transmembrane YP_001326429.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001326430.1 KEGG: sme:SMc00566 hypothetical protein YP_001326431.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001326432.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001326433.1 KEGG: sme:SMc00569 hypothetical protein YP_001326434.1 PFAM: aldo/keto reductase; KEGG: sme:SMc00570 putative oxidoreductase protein YP_001326435.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sme:SMc00571 acyl-carrier-protein S-malonyltransferase YP_001326436.1 catalyzes the formation of 3-hydroxyacyl-ACP from 3-keto-acyl-ACP; in the rhizobia this protein interacts with NodF to allow for the synthesis of highly polyunsaturated fatty acids necessary for nodulation YP_001326437.1 carries the fatty acid chain in fatty acid biosynthesis YP_001326438.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001326439.1 PFAM: aminodeoxychorismate lyase; KEGG: sme:SMc00575 hypothetical protein YP_001326440.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bur:Bcep18194_C6721 acetolactate synthase, large subunit YP_001326441.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: pfl:PFL_5026 cobalamin synthesis protein/P47K family protein YP_001326442.1 PFAM: Amidohydrolase 3; KEGG: pfl:PFL_5025 amidohydrolase family protein YP_001326443.1 KEGG: mlo:mll7671 hypothetical protein YP_001326444.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: mlo:mlr7672 transcriptional regulator YP_001326445.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mlo:mlr7674 ABC transporter, ATP-binding protein YP_001326446.1 KEGG: mlo:mlr7676 ABC transporter, binding protein YP_001326447.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr7677 ABC transporter, permease protein YP_001326448.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr7678 ABC transporter, permease protein YP_001326449.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: sme:SMc00576 hypothetical protein YP_001326450.1 Essential for recycling GMP and indirectly, cGMP YP_001326451.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001326452.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001326453.1 PFAM: SurA domain; KEGG: sme:SMc00581 putative survival protein surA precursor (peptidyl-prolyl cis-trans isomerase SurA) YP_001326454.1 PFAM: Organic solvent tolerance protein; KEGG: sme:SMc00582 organic solvent tolerance protein YP_001326455.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sme:SMc00583 hypothetical, transmembrane protein YP_001326456.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sme:SMc00584 hypothetical transmembrane protein YP_001326457.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001326458.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001326459.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc00588 putative D-galactose 1-dehydrogenase protein YP_001326460.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00589 hypothetical protein YP_001326461.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00590 putative ABC transporter ATP-binding protein YP_001326462.1 KEGG: sme:SMc00591 hypothetical/unknown signal peptide protein YP_001326463.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00592 hypothetical, transmembrane protein YP_001326464.1 PFAM: DinB family protein; KEGG: sme:SMc00593 hypothetical protein YP_001326465.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00594 putative beta-etherase (beta-aryl ether cleaving enzyme) protein YP_001326466.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001326467.1 KEGG: sme:SMc00596 hypothetical protein YP_001326468.1 PFAM: protein of unknown function DUF1470; KEGG: sme:SMc00597 hypothetical protein YP_001326469.1 PFAM: inner-membrane translocator; KEGG: sme:SMc00598 putative branched-chain amino acid transport permease protein YP_001326470.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: sme:SMc00599 probable molybdopterin MPT converting factor, subunit 2 protein YP_001326471.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: sme:SMc00600 probable molybdopterin MPT converting factor, subunit 1 protein YP_001326472.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc00601 probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase transmembrane protein YP_001326473.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001326474.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00603 short chain dehydrogenase YP_001326475.1 PFAM: porin; KEGG: sme:SMc00604 probable outer membrane protein YP_001326476.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00605 hypothetical zinc finger domain C2H2 type protein YP_001326477.1 PFAM: ribonuclease T2; KEGG: sme:SMc00606 putative ribonuclease protein YP_001326478.1 KEGG: sme:SMc00607 hypothetical signal peptide protein YP_001326479.1 PFAM: protein of unknown function DUF519; KEGG: sme:SMc00608 hypothetical protein YP_001326480.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMc00609 putative anaerobic dimethyl sulfoxide reductase chain A protein YP_001326481.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc00610 hypothetical protein YP_001326482.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001326483.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001326484.1 PFAM: protein of unknown function UPF0118; KEGG: sme:SMc00616 putative permease protein YP_001326485.1 KEGG: sme:SMc00617 hypothetical protein YP_001326486.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001326487.1 PFAM: Ppx/GppA phosphatase; KEGG: sme:SMc00619 hypothetical protein YP_001326488.1 KEGG: sme:SMc00620 hypothetical signal peptide protein YP_001326489.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc00621 adenylate cyclase 2 protein YP_001326490.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: sme:SMc00622 probable ribonuclease D protein YP_001326491.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sme:SMc01754 putative oxidoreductase protein YP_001326492.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc01755 putative transport transmembrane protein YP_001326493.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001326494.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001326495.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia have multiple copies of the groEL gene which are active under different environmental conditions; the S. meliloti protein in this cluster is not associated with a groES gene YP_001326496.1 KEGG: sme:SMc01759 hypothetical protein YP_001326497.1 KEGG: sme:SMc01760 hypothetical protein YP_001326498.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001326499.1 PFAM: regulatory protein ArsR; KEGG: sme:SMc01762 putative transcription regulator protein YP_001326500.1 KEGG: sme:SMc01763 hypothetical protein YP_001326501.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001326502.1 PFAM: RDD domain containing protein; KEGG: sme:SMc01765 hypothetical protein YP_001326503.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001326504.1 KEGG: sme:SMc01767 hypothetical protein YP_001326505.1 PFAM: regulatory protein MarR; KEGG: sme:SMc01768 putative transcription regulator protein YP_001326506.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMc01769 hypothetical protein YP_001326507.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001326508.1 PFAM: ATP-cone domain protein; KEGG: sme:SMc01771 ATP-cone domain protein YP_001326509.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: sme:SMc01772 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001326510.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001326511.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01775 putative acetyltransferase protein YP_001326512.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001326513.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001326514.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc01779 putative transport transmembrane protein YP_001326515.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001326516.1 PFAM: SmpA/OmlA domain protein; KEGG: sme:SMc01781 hypothetical protein YP_001326517.1 PFAM: Ubiquinol-cytochrome C chaperone; KEGG: sme:SMc01782 hypothetical protein YP_001326518.1 KEGG: sme:SMc01783 hypothetical protein YP_001326519.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001326520.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001326521.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001326522.1 PFAM: regulatory protein MerR; KEGG: sme:SMc01787 putative transcription regulator protein YP_001326523.1 KEGG: sme:SMc01788 hypothetical protein YP_001326530.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa0557 LysR family transcriptional regulator, probable YP_001326531.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sme:SMa0558 hypothetical protein YP_001326532.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: atu:Atu0206 hypothetical protein YP_001326533.1 PFAM: aldo/keto reductase; KEGG: bfr:BF2073 probable aldo/keto reductase YP_001326534.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMa0559 4-carboxymuconolactone decarboxylase, putative YP_001326535.1 KEGG: sme:SMa0561 hypothetical protein YP_001326536.1 PFAM: glucose sorbosone dehydrogenase; KEGG: sme:SMa0564 conserved hypothetical protein, possible oxidoreductase YP_001326537.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: bja:bll4598 hypothetical protein YP_001326539.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rle:pRL110382 putative D-xylulose reductase YP_001326540.1 KEGG: sme:SMc01791 hypothetical protein YP_001326541.1 PFAM: sugar transferase; KEGG: sme:SMc01792 putative sugar transferase protein YP_001326542.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMc01793 putative glycosyltransferase protein YP_001326543.1 PFAM: polysaccharide export protein; KEGG: sme:SMc01794 putative polysaccharide export system periplasmic transmembrane protein YP_001326544.1 TIGRFAM: exopolysaccharide transport protein family; PFAM: lipopolysaccharide biosynthesis protein; KEGG: sme:SMc01795 putative polysaccharide synthesis/transport transmembrane protein YP_001326545.1 KEGG: sme:SMc01796 hypothetical protein YP_001326546.1 PFAM: metallophosphoesterase; KEGG: sme:SMc01798 hypothetical protein YP_001326547.1 KEGG: sme:SMc01799 conserved hypothetical signal peptide protein YP_001326548.1 PFAM: cytochrome oxidase assembly; KEGG: sme:SMc01800 putative cytochrome C oxidase assembly transmembrane protein YP_001326549.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001326550.1 catalyzes the formation of putrescine from agmatine YP_001326551.1 forms a direct contact with the tRNA during translation YP_001326552.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001326553.1 PFAM: thioesterase superfamily protein; KEGG: sme:SMc01805 hypothetical protein YP_001326554.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001326555.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc01807 hypothetical protein YP_001326556.1 PFAM: CoA-binding domain protein; KEGG: sme:SMc01808 hypothetical protein YP_001326557.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_001326558.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: sme:SMc01810 hypothetical protein YP_001326559.1 PFAM: cytochrome P450; KEGG: sme:SMc01812 putative cytochrome P450-like monooxygenase protein YP_001326560.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMc01813 hypothetical protein YP_001326561.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sme:SMc04448 hypothetical protein YP_001326562.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001326563.1 binds and unfolds substrates as part of the ClpXP protease YP_001326564.1 KEGG: sme:SMc01905 probable ATP-dependent protease LA protein; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001326565.1 PFAM: histone family protein DNA-binding protein; KEGG: sme:SMc01906 histone-like protein YP_001326566.1 KEGG: sme:SMc01907 hypothetical protein YP_001326567.1 PFAM: regulatory protein MarR; KEGG: sme:SMc01908 putative transcription regulator protein YP_001326568.1 PFAM: metallophosphoesterase; KEGG: sme:SMc01909 hypothetical protein YP_001326569.1 KEGG: sme:SMc01910 hypothetical protein YP_001326570.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: sme:SMc01911 hypothetical protein YP_001326571.1 KEGG: mes:Meso_4324 Rv0623-like transcription factor YP_001326573.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: bja:bll6292 probable Hemolysin secretion protein D YP_001326574.1 TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: xft:PD1412 toxin secretion ABC transporter ATP-binding protein YP_001326575.1 KEGG: sil:SPO3673 type I secretion target repeat protein YP_001326576.1 KEGG: sha:SH0326 hypothetical protein YP_001326578.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326579.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001326580.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326581.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326582.1 KEGG: sme:SMc01916 hypothetical signal peptide protein YP_001326583.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326584.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001326585.1 KEGG: sme:SMc01919 putative NADH dehydrogenase I chain E YP_001326586.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326587.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326588.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326589.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326590.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326591.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001326592.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326593.1 Catalyzes the transfer of electrons from NADH to quinone YP_001326594.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: sme:SMc01928 probable biotin--[acetyl-CoA-carboxylase] synthetase protein YP_001326595.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: sme:SMc01929 hypothetical protein YP_001326596.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01930 hypothetical protein YP_001326597.1 PFAM: protein of unknown function DUF1467; KEGG: sme:SMc01931 hypothetical protein YP_001326598.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc01990 putative ferredoxin reductase protein YP_001326599.1 TIGRFAM: Rieske [2Fe-2S] domain protein, MocE subfamily; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMc01993 putative dioxygenase ferredoxin protein YP_001326600.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc02016 putative ferredoxin reductase protein YP_001326601.1 PFAM: Sterol desaturase; KEGG: sme:SMc02017 hypothetical protein YP_001326603.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc02018 hypothetical protein YP_001326604.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02019 putative permease ABC transporter protein YP_001326605.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02020 putative ATP binding ABC transporter protein YP_001326606.1 KEGG: sme:SMc02021 putative periplasmic binding ABC transporter protein YP_001326607.1 PFAM: regulatory protein LacI; KEGG: sme:SMc02022 putative transcription regulator protein YP_001326608.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001326609.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: sme:SMc01935 ABC transporter, permease protein YP_001326610.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01376 putative ATP-binding ABC transporter protein YP_001326611.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001326612.1 PFAM: Peptidoglycan-binding domain 1 protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc01374 hypothetical protein YP_001326613.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001326614.1 KEGG: sme:SMc01372 hypothetical protein YP_001326615.1 PFAM: response regulator receiver; KEGG: sme:SMc01371 putative 2-component receiver domain protein YP_001326616.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP YP_001326617.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001326618.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc01368 putative transport transmembrane protein YP_001326619.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc01367 hypothetical protein YP_001326620.1 PFAM: protein of unknown function DUF983; KEGG: sme:SMc01366 hypothetical protein YP_001326621.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B OB region domain; KEGG: sme:SMc01365 putative exoribonuclease II protein YP_001326622.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001326623.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: sme:SMc01363 DNA processing chain A YP_001326624.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001326625.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001326626.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001326627.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMc01359 putative oxidoreductase protein YP_001326628.1 PFAM: Auxin Efflux Carrier; KEGG: sme:SMc01358 hypothetical transmembrane protein YP_001326629.1 KEGG: sme:SMc01357 hypothetical protein YP_001326630.1 KEGG: sme:SMc01356 hypothetical protein YP_001326631.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001326632.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_001326633.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001326634.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001326635.1 KEGG: sme:SMc01351 hypothetical protein YP_001326636.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001326637.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01349 hypothetical protein YP_001326638.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis YP_001326639.1 KEGG: sme:SMc01347 hypothetical protein YP_001326640.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001326641.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001326642.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001326643.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001326644.1 PFAM: DSBA oxidoreductase; KEGG: sme:SMc01342 putative outer membrane protein YP_001326645.1 TIGRFAM: ribonuclease, Rne/Rng family; KEGG: sme:SMc01336 probable ribonuclease E protein YP_001326647.1 PFAM: cell wall hydrolase/autolysin; KEGG: sme:SMc01335 probable N-acetylmuramoyl-L-alanine amidase amic precursor transmembrane protein YP_001326648.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sme:SMc01334 probable penicillin-binding 1A transmembrane protein YP_001326649.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA YP_001326650.1 KEGG: sme:SMc01332 hypothetical/unknown protein YP_001326651.1 catalyzes the phosphorylation of NAD to NADP YP_001326652.1 KEGG: mlo:mll2032 hypothetical protein YP_001326653.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01330 putative transcription regulator protein YP_001326654.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sme:SMc01329 probable acyl carrier protein phosphodiesterase YP_001326655.1 KEGG: sme:SMc01328 hypothetical protein YP_001326656.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sme:SMc01327 putative tRNA/rRNA methyltransferase protein YP_001326657.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001326658.1 KEGG: sme:SMc01325 hypothetical/unknown protein YP_001326659.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMc01324 putative oxidoreductase protein YP_001326660.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001326661.1 Modulates Rho-dependent transcription termination YP_001326662.1 binds directly to 23S ribosomal RNA YP_001326663.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001326664.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001326665.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001326666.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001326667.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001326668.1 KEGG: sme:SMc01315 hypothetical protein YP_001326669.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001326670.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001326671.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001326672.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001326673.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001326674.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001326675.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001326676.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001326677.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001326678.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001326679.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001326680.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001326681.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001326682.1 one of the stabilizing components for the large ribosomal subunit YP_001326683.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001326684.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001326685.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001326686.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001326687.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001326688.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001326689.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001326690.1 binds 5S rRNA along with protein L5 and L25 YP_001326691.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001326692.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001326693.1 late assembly protein YP_001326694.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001326695.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001326696.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001326697.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001326698.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001326699.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001326700.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001326701.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001326702.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc01280 probable protease protein YP_001326703.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: sme:SMc01279 putative ATPase YP_001326704.1 PFAM: small multidrug resistance protein; KEGG: sme:SMc01278 probable chaperone homologue transmembrane protein YP_001326705.1 PFAM: ATP12 ATPase; KEGG: sme:SMc01277 hypothetical protein YP_001326706.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc01276 putative phosphoglycolate phosphatase protein YP_001326707.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; KEGG: sme:SMc01275 probable ribosomal large subunit pseudouridine synthase C protein YP_001326708.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001326709.1 TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; KEGG: sme:SMc01273 putative S-formylglutathione hydrolase protein YP_001326710.1 PFAM: protein of unknown function DUF1345; KEGG: sme:SMc01272 hypothetical protein YP_001326711.1 PFAM: protein of unknown function DUF188; KEGG: sme:SMc01271 conserved hypothetical protein YP_001326712.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc01270 probable alcohol dehydrogenase class III + glutathione-dependent formaldehyde dehydrogenase protein YP_001326713.1 PFAM: helix-turn-helix domain protein; bacteriophage CI repressor; KEGG: sme:SMc01269 putative transcription regulator protein YP_001326714.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001326715.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: sme:SMc01267 serine protein kinase YP_001326716.1 PFAM: protein of unknown function DUF444; KEGG: sme:SMc01266 hypothetical protein YP_001326717.1 PFAM: SpoVR family protein; KEGG: sme:SMc01265 hypothetical protein YP_001326718.1 KEGG: sme:SMc01264 hypothetical protein YP_001326719.1 KEGG: sme:SMc01263 hypothetical protein YP_001326720.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001326721.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: sme:SMc01261 putative transporter transmembrane protein YP_001326722.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sme:SMc01260 putative transcription regulator protein YP_001326723.1 PFAM: protein of unknown function DUF1624; KEGG: sme:SMc01258 hypothetical protein YP_001326724.1 PFAM: protein of unknown function DUF599; KEGG: sme:SMc01257 hypothetical protein YP_001326725.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: sme:SMc01256 probable L-serine dehydratase protein YP_001326726.1 PFAM: uncharacterised conserved protein UCP032025; KEGG: sme:SMc00995 hypothetical protein YP_001326727.1 KEGG: sme:SMc01068 hypothetical/unknown protein YP_001326728.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; KEGG: sme:SMc00996 putative penicillin-binding protein YP_001326729.1 KEGG: sme:SMc00997 hypothetical protein YP_001326730.1 PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: sme:SMc00998 conserved hypothetical signal peptide protein YP_001326731.1 PFAM: type IV pilus assembly PilZ; KEGG: sme:SMc00999 hypothetical protein YP_001326732.1 PFAM: protein of unknown function DUF1457; KEGG: sme:SMc01000 hypothetical protein YP_001326733.1 PFAM: Rhomboid family protein; KEGG: sme:SMc01001 hypothetical protein YP_001326734.1 PFAM: CBS domain containing protein; KEGG: sme:SMc01002 hypothetical protein YP_001326735.1 PFAM: Patatin; KEGG: sme:SMc01003 hypothetical protein YP_001326736.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001326737.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001326738.1 PFAM: nitrogen-fixing NifU domain protein; KEGG: sme:SMc01006 hypothetical protein YP_001326739.1 PFAM: protein of unknown function DUF37; KEGG: sme:SMc01007 hypothetical protein YP_001326740.1 KEGG: sme:SMc01008 hypothetical protein YP_001326741.1 PFAM: protein of unknown function DUF1697; KEGG: sme:SMc01009 hypothetical protein YP_001326742.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001326743.1 KEGG: sme:SMc01011 hypothetical protein YP_001326744.1 PFAM: nitroreductase; KEGG: sme:SMc01012 hypothetical protein YP_001326745.1 KEGG: sme:SMc01013 hypothetical protein YP_001326746.1 PFAM: HpcH/HpaI aldolase; KEGG: sme:SMc01014 hypothetical protein YP_001326747.1 KEGG: sme:SMc01015 hypothetical protein YP_001326748.1 KEGG: sme:SMc01016 hypothetical protein YP_001326749.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01017 putative acetyltransferase protein YP_001326750.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001326751.1 KEGG: sme:SMc01019 hypothetical protein YP_001326752.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc01020 hypothetical protein YP_001326753.1 PFAM: YceI family protein; KEGG: sme:SMc01021 hypothetical protein YP_001326754.1 PFAM: cytochrome B561; KEGG: sme:SMc01022 putative cytochrome b transmembrane protein YP_001326755.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001326756.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: sme:SMc01024 preprotein translocase SecG subunit YP_001326757.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001326758.1 KEGG: sme:SMc01026 hypothetical/unknown protein YP_001326759.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001326760.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001326761.1 KEGG: pfa:PF13_0056 hypothetical protein YP_001326762.1 PFAM: Septum formation initiator; KEGG: sme:SMc01029 hypothetical protein YP_001326763.1 PFAM: dehydrogenase E1 component; KEGG: sme:SMc01030 pyruvate dehydrogenase alpha2 subunit protein YP_001326764.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_001326765.1 TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sme:SMc01032 dihydrolipoamide S-acetyltransferase protein YP_001326766.1 PFAM: lipolytic protein G-D-S-L family; KEGG: sme:SMc01033 probable arylesterase protein YP_001326767.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01034 hypothetical protein YP_001326768.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001326769.1 PFAM: Transglycosylase-associated protein; KEGG: sme:SMc01036 hypothetical protein YP_001326770.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001326771.1 PFAM: cyclase/dehydrase; KEGG: sme:SMc01038 hypothetical protein YP_001326772.1 PFAM: CinA domain protein; KEGG: sme:SMc01039 putative competence-damage protein YP_001326773.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations YP_001326774.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; dihydroorotate dehydrogenase; KEGG: sme:SMc01041 putative NifR3-like protein YP_001326775.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; KEGG: sme:SMc01042 nitrogen regulation protein YP_001326776.1 TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sme:SMc01043 nitrogen assimilation regulatory protein YP_001326777.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc01044 probable nitrogen regulation transmembrane protein YP_001326778.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sme:SMc01045 probable nitrogen regulation protein YP_001326779.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001326780.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_001326781.1 Stimulates the elongation of poly(A) tails YP_001326782.1 PFAM: GTP-binding protein HSR1-related; KEGG: sme:SMc01049 putative GTP-binding protein YP_001326783.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001326784.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sme:SMc01052 hypothetical protein YP_001326785.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc01053 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase YP_001326786.1 KEGG: sme:SMc01054 hypothetical protein YP_001326787.1 PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: sme:SMc02124 putative sulfite reductase YP_001326788.1 PFAM: uncharacterised conserved protein UCP030820; KEGG: sme:SMc02123 hypothetical protein YP_001326789.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMc02122 probable ferredoxin--NADP reductase protein YP_001326790.1 KEGG: sme:SMb20783 putative transposase of insertion sequence ISRm2011-2, orfA protein YP_001326791.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02121 probable general L-amino acid transport ATP-binding ABC transporter protein YP_001326792.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02120 probable general L-amino acid transport permease ABC transporter protein YP_001326793.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02119 probable general L-amino acid transport permease ABC transporter protein YP_001326794.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; SMART: extracellular solute-binding protein family 3; KEGG: sme:SMc02118 probable general L-amino acid-binding periplasmic ABC transporter protein YP_001326795.1 catalyzes the formation of L-homocysteine from cystathionine YP_001326796.1 PFAM: monooxygenase FAD-binding; KEGG: sme:SMc02116 putative salicylate hydroxylase protein YP_001326797.1 KEGG: sme:SMc02115 hypothetical unknown protein YP_001326798.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc02114 hypothetical protein YP_001326799.1 TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; KEGG: sme:SMc02113 probable serine acetyltransferase protein YP_001326800.1 KEGG: sme:SMc02112 hypothetical unknown protein YP_001326801.1 TIGRFAM: phasin family protein; KEGG: sme:SMc02111 hypothetical protein YP_001326802.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001326803.1 TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: sme:SMc02109 probable ATP-dependent CLP protease ATP-binding subunit protein YP_001326804.1 PFAM: AzlC family protein; KEGG: sme:SMc02108 hypothetical protein YP_001326805.1 KEGG: sme:SMc02107 hypothetical unknown transmembrane protein YP_001326806.1 PFAM: histidine triad (HIT) protein; KEGG: sme:SMc02106 probable Hit-like protein YP_001326807.1 PFAM: protein of unknown function DUF482; KEGG: sme:SMc02105 hypothetical protein YP_001326808.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: sme:SMc02104 conserved hypothetical protein YP_001326809.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMc02103 hypothetical protein YP_001326810.1 PFAM: Domain of unknown function DUF1849; KEGG: sme:SMc02102 hypothetical protein YP_001326812.1 PFAM: ROK family protein; KEGG: bmb:BruAb2_1125 ROK family protein YP_001326813.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bmb:BruAb2_1124 taurine ABC transporter, permease protein YP_001326814.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bms:BRA1187 taurine ABC transporter, ATP-binding protein YP_001326815.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: bmb:BruAb2_1122 taurine ABC transporter, taurine-binding protein YP_001326816.1 PFAM: sulfatase; KEGG: aor:AO090012000003 beta-glucosidase-related glycosidases Pfam: Sulfatase Glyco_hydro_3 Glyco_hydro_3_C FG-GAP YP_001326817.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001326818.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001326819.1 Catalyzes the phosphorylation of UMP to UDP YP_001326820.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001326821.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001326822.1 PFAM: phosphatidate cytidylyltransferase; KEGG: sme:SMc02096 probable phosphatidate cytidylyltransferase transmembrane protein YP_001326823.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; KEGG: sme:SMc02095 hypothetical transmembrane protein YP_001326824.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sme:SMc02094 putative outer membrane transmembrane protein YP_001326825.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001326826.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001326827.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001326828.1 PFAM: protein of unknown function DUF1009; KEGG: sme:SMc02090 hypothetical protein YP_001326829.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001326830.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001326831.1 PFAM: ComEC/Rec2-related protein; KEGG: sme:SMc02086 hypothetical protein YP_001326832.1 TIGRFAM: TonB-system energizer ExbB type-1; PFAM: MotA/TolQ/ExbB proton channel; KEGG: sme:SMc02085 probable biopolymer transport transmembrane protein YP_001326833.1 TIGRFAM: TonB system transport protein ExbD type-1; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sme:SMc02084 probable biopolymer transport transmembrane protein YP_001326834.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc02083 putative methyltransferase (PCM-like) transmembrane protein YP_001326835.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: sme:SMc02082 putative outer membrane secretion protein YP_001326836.1 KEGG: sme:SMc02081 hypothetical protein YP_001326837.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001326838.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: sme:SMc02079 putative outer membrane protein YP_001326839.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sme:SMc02078 exopolysaccharide biosynthesis regulatory protein YP_001326840.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMc02077 putative exodeoxyribonuclease III protein YP_001326841.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sme:SMc02076 putative cardiolipin synthetase transmembrane protein YP_001326842.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: sme:SMc02075 hypothetical protein YP_001326843.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001326844.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001326845.1 PFAM: Sporulation domain protein; KEGG: sme:SMc02072 hypothetical protein YP_001326846.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein YP_001326847.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: sme:SMc02070 putative segregation and condensation protein A YP_001326848.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: sme:SMc02069 putative segregation and condensation protein B YP_001326849.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02068 putative ABC transporter ATP-binding protein YP_001326850.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001326851.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001326852.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: sme:SMc02065 putative SEC-independent translocase transmembrane protein YP_001326853.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001326854.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001326855.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001326856.1 KEGG: sme:SMc02061 biotin-regulated protein YP_001326857.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: sme:SMc02060 lipoprotein precursor YP_001326858.1 PFAM: protein of unknown function DUF815; KEGG: sme:SMc02059 hypothetical protein YP_001326859.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: sme:SMc02058 probable YAJC protein YP_001326860.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001326861.1 PFAM: protein of unknown function DUF498; KEGG: sme:SMc02056 hypothetical protein YP_001326862.1 KEGG: sme:SMc02055 putative phytoene synthase protein YP_001326863.1 KEGG: sme:SMc02054 hypothetical protein YP_001326864.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001326865.1 PFAM: protein of unknown function DUF1127; KEGG: sme:SMc02052 hypothetical protein YP_001326866.1 PFAM: protein of unknown function DUF1127; KEGG: sme:SMc02051 hypothetical protein YP_001326867.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001326868.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001326869.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001326870.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001326871.1 KEGG: rle:RL0897 hypothetical protein YP_001326872.1 PFAM: protein of unknown function DUF461; nuclear export factor GLE1; KEGG: sme:SMc01242 signal peptide protein YP_001326873.1 KEGG: sme:SMc01241 hypothetical protein YP_001326874.1 KEGG: sme:SMc01239 hypothetical/unknown transmembrane protein YP_001326875.1 KEGG: rpe:RPE_2428 hypothetical protein YP_001326876.1 KEGG: rpb:RPB_2537 hypothetical protein YP_001326877.1 KEGG: rpe:RPE_2430 integrase, catalytic region YP_001326878.1 KEGG: bms:BR0728 hypothetical protein YP_001326882.1 PFAM: PilT protein domain protein; KEGG: rle:RL2176 hypothetical protein YP_001326883.1 KEGG: rpe:RPE_1494 hypothetical protein YP_001326884.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: mes:Meso_4426 transcriptional regulator, MerR family YP_001326886.1 KEGG: rle:RL1929 hypothetical protein YP_001326887.1 PFAM: peptidase M41; AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: rle:RL1930 putative ATP-dependent hydrolase protein YP_001326890.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: rle:RL1932 putative modification methylase YP_001326891.1 KEGG: xcv:XCV4346 hypothetical protein YP_001326892.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_4; KEGG: bja:blr6267 transcriptional regulator YP_001326893.1 PFAM: protein of unknown function DUF336; KEGG: ret:RHE_CH02038 hypothetical protein YP_001326894.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ret:RHE_CH02037 probable short-chain dehydrogenase protein YP_001326895.1 KEGG: ret:RHE_CH02036 hypothetical protein YP_001326896.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pfo:Pfl_3278 short-chain dehydrogenase/reductase SDR YP_001326897.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: sme:SMb21555 putative potassium-efflux protein YP_001326898.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rle:pRL80073 putative cysteine desulfurase YP_001326899.1 PFAM: ChaC family protein; KEGG: rle:pRL100236 putative cation transport protein ChaC YP_001326901.1 PFAM: metallophosphoesterase; KEGG: rle:RL1938 putative phosphatase YP_001326902.1 KEGG: vch:VCA0361 hypothetical protein YP_001326903.1 KEGG: rru:Rru_A0810 hypothetical protein YP_001326904.1 KEGG: rru:Rru_A0809 hypothetical protein YP_001326905.1 PFAM: transposase IS3/IS911 family protein; KEGG: sme:SMc03278 putative transposase number 1 for insertion sequence ISRM28 YP_001326906.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMc03279 putative transposase number 2 for insertion sequence ISRM28 YP_001326907.1 PFAM: transposase IS66; KEGG: sme:SMc03280 putative transposase number 3 for insertion sequence ISRM28 YP_001326908.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: sme:SMb21045 putative reverse transcriptasematurase protein YP_001326909.1 PFAM: transposase IS66; KEGG: bms:BRA0556 IS66 family element, orf3, putative YP_001326910.1 TIGRFAM: yecA family protein; KEGG: sme:SMc03284 hypothetical/unknown protein YP_001326911.1 KEGG: rru:Rru_A0809 hypothetical protein YP_001326912.1 KEGG: bps:BPSL0567 hypothetical protein YP_001326913.1 KEGG: dps:DP2304 hypothetical protein YP_001326914.1 KEGG: rle:RL2176 hypothetical protein YP_001326915.1 PFAM: Patatin; KEGG: rpd:RPD_2292 patatin YP_001326916.1 KEGG: mes:Meso_0549 hypothetical protein YP_001326917.1 KEGG: rle:RL1943 hypothetical protein YP_001326918.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001326919.1 PFAM: protein of unknown function DUF72; KEGG: sme:SMc01236 hypothetical protein YP_001326920.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001326921.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001326922.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMa1680 hypothetical protein YP_001326923.1 KEGG: sme:SMa1682 NapD-like protein YP_001326924.1 PFAM: sulfatase; KEGG: sme:SMa1683 putative arylsulfatase YP_001326925.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: sme:SMc01232 hypothetical transmembrane protein YP_001326926.1 negatively supercoils closed circular double-stranded DNA YP_001326927.1 PFAM: Lytic transglycosylase catalytic; KEGG: sme:SMc01230 putative transglycosylase transmembrane protein YP_001326928.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01229 putative acetyltransferase (antibiotic resistance) protein YP_001326929.1 PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: sme:SMc01228 putative antibiotic resistance (kinase) protein YP_001326930.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sme:SMc01227 putative glycerol trinitrate (GTN) reductase protein YP_001326931.1 SMART: regulatory protein ArsR; KEGG: sme:SMc01226 putative transcription regulator protein YP_001326932.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01225 putative transcription regulator protein YP_001326933.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc01224 probable thioredoxin reductase protein YP_001326934.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc01223 putative transcription regulator protein YP_001326935.1 PFAM: glycosyl transferase family 2; KEGG: sme:SMc01222 putative lipopolysaccharide core biosynthesis glycosyl transferase protein YP_001326936.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMc01221 putative lipopolysaccharide core biosynthesis glycosyl transferase protein YP_001326937.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMc01220 putative lipopolysaccharide core biosynthesis glycosyl transferase protein YP_001326938.1 PFAM: glycosyl transferase group 1; KEGG: sme:SMc01219 putative lipopolysaccharide core biosynthesis mannosyltransferase protein YP_001326939.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001326940.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc01217 putative transport transmembrane protein YP_001326941.1 KEGG: sme:SMc01216 hypothetical protein YP_001326942.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001326943.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc01214 putative zinc-containing alcohol dehydrogenase protein YP_001326944.1 PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: sme:SMc01213 hypothetical transmembrane protein YP_001326945.1 PFAM: aldo/keto reductase; KEGG: rle:RL3415 putative oxidoreductase YP_001326946.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rru:Rru_A2875 transcriptional regulator, LysR family YP_001326947.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sme:SMc01212 putative transport transmembrane protein YP_001326948.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sme:SMc01211 hypothetical transmembrane protein YP_001326949.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001326950.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sme:SMc01700 putative peptidyl-prolyl cis-trans isomerase A signal peptide protein YP_001326951.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sme:SMc01208 putative peptidyl-prolyl cis-trans isomerase B protein YP_001326952.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001326953.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001326954.1 PFAM: short-chain dehydrogenase/reductase SDR; SEC-C motif domain protein; KEGG: sme:SMc01204 putative transmembrane oxidoreductase protein oxidoreductase YP_001326955.1 KEGG: rle:RL3837 hypothetical protein YP_001326956.1 PFAM: Isoprenylcysteine carboxyl methyltransferase; KEGG: sme:SMc01203 hypothetical protein YP_001326957.1 KEGG: sme:SMc01202 putative lipoprotein YP_001326958.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc01200 hypothetical protein YP_001326959.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc01698 putative oxidoreductase protein YP_001326960.1 PFAM: major facilitator superfamily MFS_1; KEGG: rle:RL2426 putative transmembrane protein YP_001326961.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_4; KEGG: sme:SMc01198 hypothetical protein YP_001326962.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: pde:Pden_2817 glutathione-dependent formaldehyde-activating, GFA YP_001326963.1 KEGG: mlo:mll7009 hypothetical protein YP_001326964.1 PFAM: type III effector Hrp-dependent outers; KEGG: sme:SMb20394 hypothetical protein YP_001326965.1 PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: sme:SMb21565 hypothetical protein YP_001326966.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia and the high GC gram-positive bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the S. meliloti protein in this cluster is associated with a groES gene and is required for regulation of the early genes involved in nodular formation YP_001326967.1 PFAM: chaperonin Cpn10; KEGG: ret:RHE_CH01238 10 kDa chaperonin, heat shock protein YP_001326968.1 PFAM: Usg family protein; KEGG: sme:SMb21568 hypothetical conserved hyothetical protein, in Caulobacter crescentus located in trpFBA operon YP_001326969.1 KEGG: ret:RHE_PF00328 hypothetical protein YP_001326970.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sme:SMa0257 probable methylamine YP_001326971.1 PFAM: Integrase catalytic region; KEGG: ret:RHE_PA00137 putative insertion sequence transposase protein YP_001326972.1 PFAM: Integrase catalytic region; KEGG: sme:SMa2047 TRm24 putative transposase YP_001326973.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc01194 putative PhnP protein YP_001326974.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sme:SMc01193 putative deoxyribonuclease YP_001326975.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001326976.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001326977.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001326978.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: sme:SMc01188 putative penicillin-binding precursor (D-alanyl-D-alanine carboxypeptidase fraction A) transmembrane protein YP_001326979.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: sme:SMc01187 putative RARE lipoprotein A precursor YP_001326981.1 KEGG: rle:pRL90054 hypothetical protein YP_001326983.1 KEGG: bmb:BruAb1_0291 hypothetical protein YP_001326984.1 KEGG: atc:AGR_pAT_554 hypothetical protein YP_001326987.1 KEGG: rle:RL2955 hypothetical protein YP_001326990.1 TIGRFAM: DNA polymerase LigD ligase region; PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sme:SMb20912 putative ATP-dependent DNA ligase protein YP_001326991.1 KEGG: sme:SMb20913 hypothetical protein YP_001326992.1 KEGG: sme:SMb21682 hypothetical protein YP_001326994.1 KEGG: csa:Csal_1402 hypothetical protein YP_001326995.1 KEGG: mes:Meso_0246 hypothetical protein YP_001326996.1 KEGG: sit:TM1040_0827 hypothetical protein YP_001326997.1 PFAM: glycoside hydrolase family 24; Peptidoglycan-binding domain 1 protein; KEGG: mlo:mll0441 hypothetical protein YP_001326999.1 KEGG: nha:Nham_2983 hypothetical protein YP_001327000.1 KEGG: mlo:mlr8544 hypothetical protein YP_001327002.1 KEGG: mes:Meso_0235 hypothetical protein YP_001327005.1 KEGG: pde:Pden_1001 hypothetical protein YP_001327006.1 TIGRFAM: phage tape measure protein; KEGG: pde:Pden_3596 phage tape measure protein YP_001327008.1 KEGG: pde:Pden_0999 hypothetical protein YP_001327009.1 KEGG: pde:Pden_0998 hypothetical protein YP_001327010.1 KEGG: pde:Pden_0996 gene transfer agent YP_001327011.1 TIGRFAM: phage protein, HK97 gp10 family; PFAM: TP901-1 ORF40 family protein; KEGG: pde:Pden_0997 phage protein, HK97 GP10 family YP_001327012.1 TIGRFAM: phage head-tail adaptor, putative YP_001327013.1 KEGG: nha:Nham_1715 hypothetical protein YP_001327014.1 KEGG: mav:MAV_0791 hypothetical protein YP_001327015.1 KEGG: sce:YOL155C ORF YP_001327016.1 KEGG: mlo:mll0461 hypothetical protein YP_001327017.1 KEGG: sit:TM1040_1619 phage conserved hypothetical protein, phiE125 gp8 YP_001327018.1 KEGG: nha:Nham_2488 hypothetical protein YP_001327019.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: phage major capsid protein HK97; KEGG: mes:Meso_1895 phage major capsid protein, HK97 family YP_001327020.1 TIGRFAM: phage prohead protease, HK97 family; PFAM: peptidase U35 phage prohead HK97; KEGG: dvl:Dvul_0868 phage prohead protease, HK97 family YP_001327021.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: dvl:Dvul_0869 phage portal protein, HK97 family YP_001327022.1 PFAM: phage Terminase; KEGG: bpm:BURPS1710b_1642 phage terminase, large subunit, putative YP_001327023.1 TIGRFAM: phage terminase, small subunit, putative, P27 family; KEGG: bpm:BURPS1710b_1678 phage terminase, small subunit, putative, P27 family YP_001327024.1 KEGG: cth:Cthe_1731 HNH endonuclease YP_001327025.1 KEGG: sme:SMa1361 hypothetical protein YP_001327031.1 KEGG: mag:amb0358 hypothetical protein YP_001327033.1 PFAM: phage integrase family protein; KEGG: atc:AGR_L_2007 hypothetical protein YP_001327034.1 KEGG: hch:HCH_03235 hypothetical protein YP_001327035.1 KEGG: sme:SMc01239 hypothetical/unknown transmembrane protein YP_001327036.1 Represses a number of genes involved in the response to DNA damage YP_001327037.1 KEGG: sme:SMc01182 hypothetical protein YP_001327038.1 KEGG: sme:SMc01181 putative transmembrane protein YP_001327039.1 KEGG: sme:SMc01180 hypothetical protein YP_001327041.1 PFAM: beta-lactamase domain protein; KEGG: aba:Acid345_3957 beta-lactamase-like YP_001327042.1 KEGG: sme:SMb20921 hypothetical protein YP_001327043.1 PFAM: small multidrug resistance protein; KEGG: sme:SMc01179 putative multidrug transmembrane resistance signal peptide protein YP_001327044.1 PFAM: small multidrug resistance protein; KEGG: sme:SMc01178 putative multidrug transmembrane resistance signal peptide protein YP_001327045.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc01175 putative oxidoreductase protein YP_001327046.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001327047.1 PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: sme:SMc01173 hypothetical protein YP_001327048.1 PFAM: Rhodanese domain protein; KEGG: sme:SMc01172 putative thiosulfate sulfurtransferase protein YP_001327049.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01171 hypothetical protein YP_001327050.1 PFAM: protein of unknown function DUF1203; KEGG: sme:SMc01170 hypothetical protein YP_001327051.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; alanine dehydrogenase/PNT domain protein; KEGG: sme:SMc01169 probable alanine dehydrogenase oxidoreductase protein YP_001327052.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc01168 putative transcription regulator protein YP_001327053.1 KEGG: sme:SMc00935 hypothetical protein YP_001327054.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001327055.1 PFAM: cation transporter; KEGG: sme:SMc00937 probable TRK system potassium uptake transmembrane protein YP_001327056.1 KEGG: sme:SMc00938 hypothetical/unknown protein YP_001327058.1 KEGG: sme:SMc01789 hypothetical signal peptide protein YP_001327060.1 PFAM: DGPFAETKE family protein; KEGG: sme:SMc00939 hypothetical protein YP_001327061.1 KEGG: sme:SMc00940 hypothetical protein YP_001327063.1 KEGG: sme:SMc00941 hypothetical/unknown protein YP_001327064.1 KEGG: sme:SMc00942 hypothetical protein YP_001327065.1 stationary phase protein that binds TrpR repressor YP_001327066.1 PFAM: molybdopterin binding domain; KEGG: sme:SMc00944 hypothetical protein YP_001327067.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001327068.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: sme:SMc00946 hypothetical protein YP_001327069.1 PFAM: nitrogen regulatory protein P-II; KEGG: atc:AGR_C_3252 nitrogen regulatory protein P-II YP_001327070.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein YP_001327071.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: sme:SMc00949 hypothetical protein YP_001327072.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ret:RHE_CH02680 probable ferrichrome ABC transporter, ATP-binding protein YP_001327073.1 PFAM: transport system permease protein; KEGG: ret:RHE_CH02681 probable ferrichrome ABC transporter, permease protein YP_001327074.1 PFAM: transport system permease protein; KEGG: ret:RHE_CH02682 probable ferrichrome ABC transporter, permease protein YP_001327075.1 PFAM: periplasmic binding protein; KEGG: ret:RHE_CH02683 probable ferrichrome ABC transporter, substrate-binding protein YP_001327076.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ret:RHE_PB00016 probable transcriptional regulator protein, LysR family YP_001327077.1 PFAM: Invasion associated locus B family protein; KEGG: sme:SMc00950 putative signal peptide protein YP_001327078.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc00951 hypothetical transmembrane protein YP_001327079.1 PFAM: DSBA oxidoreductase; KEGG: sme:SMc00952 hypothetical protein YP_001327080.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc04450 probable transcription-repair coupling factor (TRCF) protein YP_001327081.1 PFAM: protein of unknown function DUF339; KEGG: sme:SMc00227 hypothetical protein YP_001327082.1 catalyzes branch migration in Holliday junction intermediates YP_001327083.1 PFAM: protein of unknown function DUF502; KEGG: sme:SMc00229 hypothetical protein YP_001327084.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00230 putative acetyltransferase YP_001327085.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001327086.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001327087.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; PFAM: Na+cotransporter; KEGG: sme:SMc00233 putative phosphate:Na+ symporter, PNaS family YP_001327088.1 KEGG: sme:SMc00234 putative peptidyl-prolyl CIS-trans isomerase protein YP_001327089.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001327090.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001327091.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001327092.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: sme:SMc00238 probable molybdopterin biosynthesis protein YP_001327093.1 KEGG: sme:SMc00239 hypothetical protein YP_001327094.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sme:SMc00240 hypothetical transmembrane protein YP_001327095.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc00241 putative transcription regulator protein YP_001327096.1 PFAM: basic membrane lipoprotein; KEGG: sme:SMc00242 hypothetical signal peptide protein YP_001327097.1 PFAM: inner-membrane translocator; KEGG: sme:SMc00244 putative transport system permease ABC transporter protein YP_001327098.1 PFAM: inner-membrane translocator; KEGG: sme:SMc00243 putative transport system permease ABC transporter protein YP_001327099.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00245 putative ABC transporter ATP-binding protein YP_001327100.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00246 probable quinone oxidoreductase protein YP_001327101.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc00247 phosphatidylcholine synthase YP_001327102.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: sme:SMc00316 2-octaprenyl-6-methoxyphenyl hydroxylase YP_001327103.1 PFAM: Auxin Efflux Carrier; KEGG: sme:SMc00317 hypothetical transmembrane protein YP_001327104.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: sme:SMc00248 putative cytochrome C-type biogenesis protein YP_001327105.1 TIGRFAM: methyltransferase FkbM family; KEGG: rpd:RPD_2545 methyltransferase FkbM YP_001327106.1 KEGG: sme:SMc00251 hypothetical protein YP_001327107.1 TIGRFAM: Ku family containing protein; PFAM: Ku domain protein; KEGG: sme:SMb21406 hypothetical protein YP_001327108.1 TIGRFAM: Ku family containing protein; PFAM: Ku domain protein; KEGG: sme:SMb21407 hypothetical protein YP_001327109.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ade:Adeh_0876 methyltransferase type 11 YP_001327110.1 KEGG: sme:SMc00252 hypothetical signal peptide protein YP_001327111.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMc00253 hypothetical signal peptide protein YP_001327112.1 PFAM: protein of unknown function DUF1236; KEGG: sme:SMc00254 hypothetical protein YP_001327113.1 KEGG: sme:SMc00255 hypothetical protein YP_001327114.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMc00256 putative transcription regulator protein YP_001327115.1 PFAM: porin; KEGG: sme:SMc00257 probable outer-membrane protein YP_001327116.1 KEGG: sme:SMc00258 hypothetical signal peptide protein YP_001327117.1 KEGG: sme:SMc00259 hypothetical protein YP_001327118.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00260 putative oxidoreductase protein YP_001327119.1 activates fatty acids by binding to coenzyme A YP_001327120.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001327121.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sme:SMc00263 putative transcription regulator protein YP_001327122.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00264 putative oxidoreductase protein YP_001327123.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMc00265 putative periplasmic binding protein YP_001327124.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMc00266 putative transmembrane protein YP_001327125.1 KEGG: sme:SMc00280 hypothetical protein YP_001327126.1 KEGG: sme:SMc00249 hypothetical protein YP_001327127.1 PFAM: ETC complex I subunit conserved region; KEGG: sme:SMc00287 putative oxidoreductase protein YP_001327128.1 PFAM: protein of unknown function DUF192; KEGG: sme:SMc00288 hypothetical signal peptide protein YP_001327129.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMc00289 putative cold shock transcription regulator protein YP_001327130.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc00290 probable lactoylglutathione lyase methylglyoxalase protein YP_001327131.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: sme:SMc00291 hypothetical lipoprotein YP_001327132.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: sme:SMc00292 probable single-stranded-DNA-specific exonuclease protein YP_001327133.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001327134.1 PFAM: aminotransferase class I and II; KEGG: sme:SMc00294 probable aminotransferase protein YP_001327135.1 KEGG: sme:SMc00295 hypothetical protein YP_001327136.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: sme:SMc00296 poly3-hydroxybutyrate polymerase protein YP_001327137.1 Regulatory factor involved in maltose metabolism YP_001327138.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001327139.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001327140.1 PFAM: beta-lactamase; KEGG: sme:SMa1953 putative beta-lactamase YP_001327141.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMa1954 putative LysR-family transcriptional regulator YP_001327142.1 catalyzes the conversion of NADPH to NADH YP_001327143.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; FeS assembly scaffold SufA; PFAM: HesB/YadR/YfhF-family protein; KEGG: sme:SMc00301 hypothetical protein YP_001327144.1 TIGRFAM: FeS assembly SUF system protein; PFAM: protein of unknown function DUF59; KEGG: sme:SMc00302 hypothetical protein YP_001327145.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc00533 putative pyridoxal-phosphate-dependent aminotransferase protein YP_001327146.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: sme:SMc00532 hypothetical protein YP_001327147.1 TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00531 putative ABC transporter ATP-binding protein YP_001327148.1 with SufCD activates cysteine desulfurase SufS YP_001327149.1 PFAM: aminotransferase class V; KEGG: sme:SMc00529 putative pyridoxal-phosphate-dependent aminotransferase protein YP_001327150.1 KEGG: sme:SMc00528 hypothetical protein YP_001327151.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMb20523 hypothetical protein transmembrane YP_001327152.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001327153.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001327154.1 KEGG: sme:SMc00525 hypothetical protein YP_001327155.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMc00524 putative bacterioferritin comigratory protein YP_001327156.1 PFAM: protein of unknown function DUF455; KEGG: ret:RHE_CH02263 hypothetical protein YP_001327157.1 PFAM: peptidase M23B; KEGG: sme:SMc00539 hypothetical protein YP_001327158.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc00522 putative ATP-dependent RNA helicase protein YP_001327159.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc00521 hypothetical protein YP_001327160.1 PFAM: TfoX domain protein; KEGG: sme:SMc00520 hypothetical protein YP_001327161.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; molybdopterin binding domain; KEGG: sme:SMc00519 hypothetical protein YP_001327162.1 KEGG: sme:SMc00518 xanthine dehydrogenase accessory factor YP_001327163.1 PFAM: protein of unknown function DUF182; KEGG: sme:SMc00517 hypothetical protein YP_001327164.1 PFAM: VWA containing CoxE family protein; KEGG: sme:SMc00516 hypothetical protein YP_001327165.1 PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; KEGG: sme:SMc00515 hypothetical protein YP_001327166.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sme:SMc00514 putative monooxygenase protein YP_001327167.1 PFAM: Extracellular ligand-binding receptor; KEGG: sme:SMc00513 putative amino acid-binding periplasmic protein YP_001327168.1 PFAM: peptidase S58 DmpA; KEGG: sme:SMc00512 hypothetical protein YP_001327169.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: sme:SMc00511 probable D-ribulose-5-phosphate 3-epimerase protein YP_001327170.1 KEGG: sme:SMc00510 hypothetical protein YP_001327171.1 KEGG: sme:SMc00509 hypothetical protein YP_001327172.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001327173.1 PFAM: type IV pilus assembly PilZ; KEGG: sme:SMc00507 hypothetical/unknown protein YP_001327174.1 KEGG: sme:SMc00506 hypothetical protein YP_001327175.1 PFAM: protein of unknown function DUF1234; KEGG: sme:SMc00505 hypothetical protein YP_001327176.1 PFAM: protein of unknown function DUF1476; KEGG: sme:SMc00496 hypothetical protein YP_001327177.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001327178.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_001327179.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001327180.1 KEGG: sme:SMc00492 hypothetical protein YP_001327181.1 KEGG: sme:SMc00491 hypothetical protein YP_001327182.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMc00490 putative transcription regulator protein YP_001327183.1 KEGG: sme:SMc00489 hypothetical/unknown signal peptide protein YP_001327184.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001327185.1 PFAM: BolA family protein; KEGG: sme:SMc00487 hypothetical protein YP_001327186.1 KEGG: atc:AGR_C_3399 hypothetical protein YP_001327187.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sme:SMc00538 monothiol glutaredoxin YP_001327188.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00537 putative transport protein YP_001327189.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00536 putative transport protein YP_001327190.1 PFAM: inositol monophosphatase; KEGG: sme:SMc00535 hypothetical protein YP_001327191.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001327192.1 catalyzes the formation of glutamate from glutamine YP_001327193.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001327194.1 SMART: AAA ATPase; KEGG: sme:SMc00484 hypothetical protein YP_001327195.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001327196.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sme:SMc00482 hypothetical protein YP_001327197.1 KEGG: sme:SMc00481 hypothetical protein YP_001327198.1 Converts isocitrate to alpha ketoglutarate YP_001327199.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001327200.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001327201.1 PFAM: Indigoidine synthase A family protein; KEGG: sme:SMc00472 hypothetical protein YP_001327202.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc00471 putative sensor histidine kinase transmembrane protein YP_001327203.1 KEGG: sme:SMc00470 hypothetical protein YP_001327204.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sme:SMc00469 putative dnaK suppresor protein YP_001327205.1 PFAM: Phosphoglycerate mutase; KEGG: sme:SMc00468 hypothetical protein YP_001327206.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: sme:SMc00467 hypothetical protein YP_001327207.1 PFAM: conserved hypothetical protein 1620; KEGG: sme:SMc00466 hypothetical protein YP_001327208.1 KEGG: sme:SMc00548 conserved hypothetical signal peptide protein YP_001327209.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sme:SMc00465 probable 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase protein YP_001327210.1 TIGRFAM: dihydroneopterin aldolase; KEGG: sme:SMc00463 probable dihydroneopterin aldolase DhnA lyase folate biosynthesis protein YP_001327211.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; KEGG: sme:SMc00462 probable dihydropteroate synthase antibiotic resistance transferase folate protein YP_001327212.1 PFAM: protein of unknown function DUF922; KEGG: sme:SMc00194 hypothetical protein YP_001327213.1 PFAM: ferredoxin; KEGG: sme:SMc00192 probable ferredoxin, 2FE-2S FdiI electron transport iron-sulfur protein YP_001327214.1 PFAM: Hpt domain protein; KEGG: sme:SMc00191 hypothetical protein YP_001327215.1 PFAM: chemotaxis sensory transducer; KEGG: sme:SMc00190 hypothetical protein YP_001327216.1 PFAM: cytochrome c1; KEGG: sme:SMc00189 ubiquinol-cytochrome c reductase cytochrome c1 subunit YP_001327217.1 PFAM: Cytochrome b/b6 domain; KEGG: sme:SMc00188 ubiquinol-cytochrome c reductase cytochrome b subunit YP_001327218.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMc00187 ubiquinol-cytochrome c reductase iron-sulfur subunit YP_001327219.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein YP_001327220.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00185 putative ABC transporter ATP-binding transmembrane transmembrane protein YP_001327221.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sme:SMc00184 putative tRNA/rRNA methyltransferase protein YP_001327222.1 PFAM: NADPH-dependent FMN reductase; KEGG: sme:SMc00183 hypothetical protein YP_001327223.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sme:SMc00182 putative transcription regulator protein YP_001327224.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00196 putative transport protein transmembrane YP_001327225.1 KEGG: sme:SMc00181 hypothetical protein YP_001327226.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001327227.1 PFAM: transport-associated; KEGG: sme:SMc00179 hypothetical/unknown protein YP_001327228.1 PFAM: protein of unknown function DUF330; KEGG: sme:SMc00177 hypothetical protein YP_001327229.1 PFAM: Mammalian cell entry related domain protein; KEGG: sme:SMc00176 conserved hypothetical protein YP_001327230.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00175 putative ABC transporter ATP-binding protein YP_001327231.1 PFAM: protein of unknown function DUF140; KEGG: sme:SMc00174 hypothetical transmembrane protein YP_001327232.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sme:SMc00459 putative mandelate racemase / muconate cycloisomerase YP_001327233.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00172 putative transport protein transmembrane YP_001327234.1 PFAM: metallophosphoesterase; KEGG: sme:SMc00171 hypothetical protein YP_001327235.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_001327236.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc00170 putative transcription regulator HSL-dependent protein YP_001327237.1 PFAM: autoinducer synthesis protein; KEGG: sme:SMc00168 putative autoinducer synthase protein YP_001327238.1 KEGG: sme:SMc00167 conserved hypothetical signal peptide protein YP_001327239.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: sme:SMc00166 putative oxidoreductase NAD protein YP_001327240.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00165 short chain dehydrogenase YP_001327241.1 PFAM: Ankyrin; KEGG: sus:Acid_2197 ankyrin YP_001327242.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001327243.1 PFAM: sulfatase; KEGG: sme:SMc00195 cyclic beta-1,2-glucan modification transmembrane protein YP_001327244.1 KEGG: sme:SMc00157 hypothetical protein YP_001327245.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc00156 hypothetical protein YP_001327246.1 TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; KEGG: sme:SMc00155 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001327247.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001327248.1 KEGG: sme:SMc00153 hypothetical protein YP_001327249.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001327250.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001327251.1 KEGG: sme:SMc00150 hypothetical protein YP_001327252.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001327253.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: sme:SMc00148 hypothetical protein YP_001327254.1 KEGG: sme:SMc00147 hypothetical protein YP_001327255.1 PFAM: regulatory protein MarR; KEGG: sme:SMc00146 putative transcription regulator protein YP_001327256.1 PFAM: protein of unknown function DUF971; KEGG: sme:SMc00145 hypothetical protein YP_001327257.1 KEGG: sme:SMc00145 hypothetical protein YP_001327258.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001327259.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00197 hypothetical protein YP_001327260.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001327261.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: sme:SMc00142 probable molybdopterin-guanine dinucleotide biosynthesis protein YP_001327262.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mgm:Mmc1_2003 Sel1 domain protein repeat-containing protein YP_001327263.1 PFAM: OmpA/MotB domain protein; KEGG: sme:SMc00141 hypothetical protein YP_001327264.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: sme:SMc00140 putative amino-acid binding periplasmic protein YP_001327265.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00139 putative amino acid transport system permease protein YP_001327266.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00138 putative amino acid transport system permease protein YP_001327267.1 PFAM: Usg family protein; KEGG: sme:SMc00137 hypothetical protein YP_001327268.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00136 putative oxidoreductase protein YP_001327269.1 KEGG: sme:SMc00135 hypothetical protein YP_001327270.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; Methyltransferase type 11; Methyltransferase type 12; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc00134 hypothetical protein YP_001327271.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMc00133 putative oxidoreductase protein YP_001327272.1 KEGG: sme:SMc00132 hypothetical protein YP_001327273.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc00131 putative transcription regulator protein YP_001327274.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: sme:SMc04210 hypothetical protein YP_001327275.1 PFAM: nuclease (SNase domain protein); KEGG: sme:SMc04211 hypothetical protein YP_001327276.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc04212 putative sensor histidine kinase transmembrane protein YP_001327277.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001327278.1 PFAM: diacylglycerol kinase; KEGG: sme:SMc04213 diacylglycerol kinase protein YP_001327279.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001327280.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001327281.1 PFAM: protein of unknown function DUF1289; KEGG: sme:SMc04216 hypothetical protein YP_001327282.1 KEGG: sme:SMc04217 hypothetical transmembrane signal peptide protein YP_001327283.1 PFAM: ABC-2 type transporter; KEGG: sme:SMc04218 putative transport transmembrane protein YP_001327284.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc04219 putative ATP-binding ABC transporter protein YP_001327285.1 PFAM: regulatory protein ArsR; KEGG: sme:SMc04220 putative transcription regulator protein YP_001327286.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMa1057 hypothetical protein YP_001327287.1 PFAM: Extensin family protein; KEGG: sme:SMc04225 hypothetical protein YP_001327288.1 PFAM: protease inhibitor Kazal-type; SMART: proteinase inhibitor I1 Kazal; KEGG: sme:SMc04226 hypothetical lipoprotein transmembrane YP_001327289.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Cache type 2 domain protein; KEGG: sme:SMc04227 probable chemoreceptor (methyl-accepting chemotaxis) transmembrane protein YP_001327290.1 PFAM: thioesterase superfamily protein; KEGG: sme:SMc04228 putative acyl-CoA thioester hydrolase YP_001327291.1 KEGG: sme:SMc04229 hypothetical protein YP_001327292.1 PFAM: protein of unknown function DUF486; KEGG: sme:SMc04230 hypothetical transmembrane signal peptide protein YP_001327293.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001327294.1 KEGG: sme:SMc04232 hypothetical glycine rich transmembrane protein YP_001327295.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sme:SMc04233 hypothetical DnaJ domain protein YP_001327296.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMc04234 putative cold shock-like transcription regulator protein YP_001327297.1 PFAM: dihydrouridine synthase DuS; KEGG: sme:SMc04235 tRNA-dihydrouridine synthase A YP_001327298.1 PFAM: phage integrase family protein; KEGG: pfl:PFL_1976 site-specific recombinase, phage integrase family YP_001327299.1 KEGG: sdn:Sden_1215 hypothetical protein YP_001327302.1 KEGG: rle:RL1144 hypothetical protein YP_001327303.1 KEGG: mlo:mlr2725 hypothetical protein YP_001327304.1 KEGG: mlo:mlr9067 hypothetical protein YP_001327305.1 PFAM: Thioredoxin domain; KEGG: sme:SMc02761 probable thioredoxin protein YP_001327306.1 PFAM: Necrosis inducing; KEGG: bld:BLi01595 hypothetical protein YP_001327307.1 KEGG: atc:AGR_C_824 hypothetical protein YP_001327308.1 KEGG: sme:SMc04183 putative transmembrane protein YP_001327310.1 KEGG: psp:PSPPH_2395 hypothetical protein YP_001327311.1 KEGG: pae:PA0643 hypothetical protein YP_001327313.1 KEGG: rsp:RSP_2990 hypothetical protein YP_001327314.1 KEGG: aba:Acid345_3157 hypothetical protein YP_001327315.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_001327318.1 KEGG: rsp:RSP_2351 hypothetical protein YP_001327321.1 KEGG: nha:Nham_1419 phage major tail protein, TP901-1 YP_001327325.1 KEGG: lma:LmjF34.0690 hypothetical protein, conserved YP_001327326.1 PFAM: phage major capsid protein E; KEGG: hch:HCH_02898 type II secretory pathway, pullulanase PulA and related glycosidase YP_001327327.1 KEGG: gox:GOX2342 hypothetical protein YP_001327328.1 KEGG: bxe:Bxe_A3062 hypothetical protein YP_001327329.1 PFAM: peptidase S49; KEGG: rsp:RSP_3784 peptidase U7 YP_001327330.1 TIGRFAM: phage portal protein, lambda family; PFAM: phage portal protein lambda; KEGG: gox:GOX2339 bacteriophage capsid structural protein YP_001327332.1 PFAM: phage terminase GpA; KEGG: mca:MCA2658 prophage LambdaMc01, terminase, large subunit YP_001327334.1 KEGG: xfa:XF0515 hypothetical protein YP_001327335.1 PFAM: transcription antitermination protein NusG; KEGG: atc:AGR_C_797 transcription antitermination protein NusG YP_001327336.1 KEGG: atc:AGR_C_796 hypothetical protein YP_001327337.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb21471 hypothetical protein YP_001327338.1 KEGG: atc:AGR_C_795 hypothetical protein YP_001327339.1 PFAM: MT-A70 family protein; KEGG: mgm:Mmc1_2604 MT-A70 family protein YP_001327344.1 KEGG: mes:Meso_1194 hypothetical protein YP_001327345.1 PFAM: peptidase S24 S26A and S26B; SMART: helix-turn-helix domain protein; KEGG: nha:Nham_3352 putative phage repressor YP_001327349.1 KEGG: pde:Pden_0257 hypothetical protein YP_001327350.1 KEGG: mlo:mlr8516 hypothetical protein YP_001327351.1 KEGG: mkm:Mkms_2959 HNH endonuclease YP_001327352.1 KEGG: bam:Bamb_2416 hypothetical protein YP_001327353.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sme:SMa1727 putative hydrolase YP_001327355.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; sterile alpha motif SAM protein; Sterile alpha motif homology 2; KEGG: sme:SMa1591 putative adenylate cyclase YP_001327356.1 KEGG: sme:SMb21682 hypothetical protein YP_001327357.1 KEGG: rle:pRL110469 hypothetical protein YP_001327358.1 KEGG: sme:SMb21683 hypothetical protein YP_001327359.1 KEGG: sme:SMc04236 putative glycine-rich cell wall structural transmembrane protein YP_001327360.1 KEGG: sme:SMc04237 hypothetical protein YP_001327361.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMc04238 hypothetical protein YP_001327362.1 KEGG: sme:SMc04239 hypothetical protein YP_001327363.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc04240 hypothetical protein YP_001327364.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sme:SMc04241 putative acetyltransferase protein YP_001327365.1 KEGG: sme:SMc04242 putative zinc uptake regulation protein YP_001327366.1 PFAM: ABC-3 protein; KEGG: sme:SMc04243 probable high-affinity zinc uptake system membrane ABC transporter protein YP_001327367.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc04244 probable high-affinity zinc uptake system ATP-binding ABC transporter protein YP_001327368.1 PFAM: periplasmic solute binding protein; KEGG: sme:SMc04245 probable high-affinity zinc uptake system ABC transporter protein YP_001327369.1 PFAM: LmbE family protein; KEGG: vei:Veis_0048 LmbE family protein YP_001327370.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: jan:Jann_1287 ABC transporter related YP_001327371.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sco:SCO1063 putative sugar transport integral membrane protein YP_001327372.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mpa:MAP1768c sugar ABC transporter, permease protein YP_001327373.1 PFAM: extracellular solute-binding protein family 1; KEGG: gvi:glr3199 sugar binding protein YP_001327375.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: ret:RHE_PA00081 probable insertion sequence ATP-binding protein, IS21 family YP_001327376.1 PFAM: Integrase catalytic region; KEGG: bja:bll1940 putative transposase YP_001327377.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpa:RPA1110 putative 3-oxoacyl-acyl carrier protein reductase YP_001327378.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rsp:RSP_3893 transcriptional regulator, GntR family YP_001327379.1 KEGG: sme:SMc04246 hypothetical transmembrane signal peptide protein YP_001327380.1 PFAM: glycoside hydrolase family 43; KEGG: sme:SMc04247 putative beta-xylosidase protein YP_001327381.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMc04248 hypothetical protein YP_001327382.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMc04249 hypothetical protein YP_001327383.1 PFAM: histidinol dehydrogenase; KEGG: reh:H16_A1694 histidinol dehydrogenase YP_001327384.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: csa:Csal_2087 transcriptional regulator, XRE family with cupin sensor protein YP_001327385.1 PFAM: extracellular solute-binding protein family 1; KEGG: bmb:BruAb2_0855 hypothetical spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein YP_001327386.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bmb:BruAb2_0854 hypothetical spermidine/putrescine ABC transporter, ATP-binding protein YP_001327387.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bms:BRA0328 spermidine/putrescine ABC transporter, permease protein, putative YP_001327388.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1751 putative ABC transporter, permease protein YP_001327389.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMc04251 putative mannitol-binding periplasmic signal peptide protein YP_001327391.1 PFAM: aldo/keto reductase; KEGG: sme:SMc04252 putative oxidoreductase protein YP_001327392.1 PFAM: oxidoreductase domain protein; dihydrodipicolinate reductase; homoserine dehydrogenase NAD-binding; KEGG: sme:SMc04253 putative oxidoreductase protein YP_001327393.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc04254 hypothetical protein YP_001327394.1 PFAM: glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: sme:SMc04255 putative beta-mannosidase protein YP_001327395.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc04256 putative ATP-binding ABC transporter protein YP_001327396.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04257 putative transport system permease ABC transporter protein YP_001327397.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04258 putative transport system permease ABC transporter protein YP_001327398.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc04259 putative periplasmic binding ABC transporter signal peptide protein YP_001327400.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMc04260 putative transcription regulator protein YP_001327401.1 KEGG: sme:SMc04261 hypothetical protein YP_001327402.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001327403.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMc04264 putative transcription regulator protein YP_001327404.1 KEGG: sme:SMc04265 hypothetical protein YP_001327405.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc04266 hypothetical protein YP_001327406.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001327407.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc04270 putative dehydrogenase protein YP_001327408.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001327409.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001327410.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: sme:SMc04277 putative (3R)-hydroxymyristoyl-[acyl carrier] dehydratase transmembrane protein YP_001327411.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001327412.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: atc:AGR_C_2948 probable transcriptional activator (ORF-240) YP_001327413.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001327414.1 PFAM: aminotransferase class I and II; KEGG: sme:SMc04281 probable cobalamin biosynthesis protein pyridoxal-phosphate-dependent aminotransferase YP_001327415.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001327416.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc04284 probable uroporphyrin-III C-methyltransferase protein YP_001327417.1 KEGG: sme:SMc04285 probable cobalamin biosynthesis protein YP_001327418.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMc04286 hypothetical transmembrane protein YP_001327419.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc04288 putative peptide transport ATP-binding ABC transporter protein YP_001327420.1 PFAM: Acetamidase/Formamidase; KEGG: sme:SMc04290 hypothetical protein YP_001327421.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc04293 putative peptide-binding periplasmic ABC transporter protein YP_001327422.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04294 putative peptide transport system permease ABC transporter protein YP_001327423.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04295 putative peptide transport system permease ABC transporter protein YP_001327424.1 PFAM: ANTAR domain protein; KEGG: sme:SMc04297 putative transcription regulator protein YP_001327425.1 KEGG: sme:SMc04301 putative regulator protein YP_001327426.1 KEGG: rpe:RPE_3246 PilT protein domain protein YP_001327427.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: atc:AGR_L_3039 hypothetical protein YP_001327428.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001327429.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001327430.1 TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sme:SMc04304 probable cobalamine biosynthesis protein YP_001327431.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001327432.1 KEGG: sme:SMc04306 hypothetical protein YP_001327433.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sme:SMc04307 putative adenylate/guanylate cyclase transmembrane protein YP_001327434.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc04308 putative oxidoreductase protein YP_001327435.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001327436.1 KEGG: sme:SMc04310 hypothetical protein YP_001327437.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc04311 hypothetical transmembrane protein YP_001327438.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc04439 putative glycine betaine transport ATP-binding ABC transporter protein YP_001327439.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: sme:SMc04314 hypothetical protein YP_001327440.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc04315 putative transcription regulator protein YP_001327441.1 catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine YP_001327442.1 PFAM: acyltransferase 3; KEGG: rde:RD1_B0055 acyltransferase family protein YP_001327443.1 KEGG: sme:SMc04328 hypothetical lipoprotein signal peptide YP_001327444.1 KEGG: sme:SMc04329 hypothetical protein YP_001327445.1 PFAM: trimethylamine methyltransferase; KEGG: sme:SMc04330 putative trimethylamine methyltransferase protein YP_001327446.1 PFAM: Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: sme:SMc04331 putative dimethylamine corrinoid protein YP_001327447.1 KEGG: sme:SMc04333 hypothetical protein YP_001327448.1 PFAM: Entericidin EcnAB; KEGG: ret:RHE_CH02170 hypothetical protein YP_001327449.1 KEGG: sme:SMc04335 hypothetical lipoprotein transmembrane YP_001327450.1 PFAM: BA14K family protein; KEGG: sme:SMc04336 hypothetical transmembrane signal peptide protein YP_001327451.1 KEGG: sme:SMc04337 hypothetical protein YP_001327452.1 KEGG: sme:SMc04339 hypothetical protein YP_001327453.1 PFAM: methylenetetrahydrofolate reductase; KEGG: sme:SMc04340 putative oxidoreductase protein YP_001327454.1 catalyzes the transfer of the N5-methyl group from (6S)-methyl tetrahydrofolate to the cobalt center of a corrinoid iron-sulfur protein YP_001327455.1 KEGG: sme:SMc04345 hypothetical protein YP_001327456.1 PFAM: ferredoxin; KEGG: sme:SMc04347 hypothetical protein YP_001327457.1 PFAM: Chloramphenicol phosphotransferase family protein; KEGG: sme:SMc04451 putative chloramphenicol phosphotransferase protein YP_001327458.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc04163 putative transcription regulator protein YP_001327459.1 KEGG: sme:SMc04164 hypothetical protein YP_001327460.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc04165 putative oxidoreductase protein YP_001327461.1 KEGG: sme:SMc04166 hypothetical protein YP_001327462.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: sme:SMc04167 putative histidine-rich transporter transmembrane protein YP_001327463.1 PFAM: protein of unknown function DUF156; KEGG: sme:SMc04168 hypothetical protein YP_001327464.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMc04169 putative transcription regulator protein YP_001327465.1 PFAM: response regulator receiver; KEGG: sme:SMc04170 putative two 2-component receiver domains protein YP_001327466.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sme:SMc04171 putative hemolysin-type calcium-binding protein YP_001327467.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: sme:SMc04173 hypothetical protein YP_001327468.1 KEGG: sme:SMc04174 hypothetical signal peptide protein YP_001327469.1 PFAM: Integral membrane protein TerC; KEGG: sme:SMc04175 putative transmembrane protein YP_001327470.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMc04176 putative transmembrane protein YP_001327471.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc04177 hypothetical protein YP_001327472.1 PFAM: protein of unknown function DUF924; KEGG: sme:SMc04178 hypothetical protein YP_001327473.1 PFAM: Citrate transporter; TrkA-C domain protein; KEGG: sme:SMc04179 putative transmembrane protein YP_001327474.1 KEGG: sme:SMc04180 putative transmembrane protein YP_001327475.1 KEGG: sme:SMc04181 putative transmembrane protein YP_001327476.1 KEGG: sme:SMc04182 hypothetical protein YP_001327477.1 KEGG: sme:SMb20921 hypothetical protein YP_001327478.1 KEGG: sme:SMc04183 putative transmembrane protein YP_001327479.1 TIGRFAM: methyltransferase FkbM family; KEGG: rpd:RPD_2545 methyltransferase FkbM YP_001327480.1 KEGG: gvi:gll2178 hypothetical protein YP_001327482.1 KEGG: mmr:Mmar10_2764 hypothetical protein YP_001327483.1 KEGG: sme:SMc04186 hypothetical protein YP_001327484.1 KEGG: mmu:239611 mucin 19 YP_001327485.1 KEGG: mes:Meso_0238 hypothetical protein YP_001327487.1 KEGG: mlo:mll0449 hypothetical protein YP_001327489.1 KEGG: mlo:mll0452 hypothetical protein YP_001327490.1 KEGG: mes:Meso_0233 hypothetical protein YP_001327492.1 KEGG: zmo:ZMO0389 constituent protein YP_001327500.1 KEGG: zmo:ZMO0387 major head protein YP_001327505.1 KEGG: nfa:nfa27910 hypothetical protein YP_001327508.1 KEGG: zmo:ZMO0380 putative portal protein YP_001327509.1 PFAM: protein of unknown function DUF264; KEGG: sme:SMc04187 probable DNA packaging protein GP2 YP_001327510.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc04188 hypothetical protein YP_001327511.1 KEGG: sme:SMc04189 hypothetical protein YP_001327512.1 KEGG: sme:SMc04190 conserved hypothetical signal peptide protein YP_001327513.1 KEGG: sme:SMc04191 hypothetical protein YP_001327516.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: ret:RHE_PA00081 probable insertion sequence ATP-binding protein, IS21 family YP_001327517.1 PFAM: Integrase catalytic region; KEGG: bja:bll1940 putative transposase YP_001327518.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001327519.1 KEGG: sme:SMc04194 putative transmembrane protein YP_001327521.1 PFAM: BA14K family protein; KEGG: sme:SMa0639 hypothetical protein YP_001327522.1 KEGG: sme:SMc04196 hypothetical protein YP_001327523.1 PFAM: Chromosomal replication initiator DnaA domain; KEGG: sme:SMc04197 hypothetical protein YP_001327524.1 PFAM: peptidase S24 S26A and S26B; KEGG: sme:SMc04198 putative phage repressor protein YP_001327525.1 KEGG: sme:SMc04199 hypothetical protein YP_001327526.1 KEGG: sme:SMc04200 hypothetical signal peptide protein YP_001327527.1 PFAM: pentapeptide repeat protein; KEGG: sme:SMc04201 putative signal peptide protein YP_001327528.1 PFAM: import inner membrane translocase subunit Tim44; KEGG: sme:SMc04202 putative transmembrane protein YP_001327529.1 KEGG: sme:SMc04209 hypothetical protein YP_001327530.1 KEGG: sme:SMc04267 hypothetical protein YP_001327531.1 PFAM: Thioredoxin domain; KEGG: sme:SMc02761 probable thioredoxin protein YP_001327532.1 PFAM: Necrosis inducing; KEGG: bld:BLi01595 hypothetical protein YP_001327533.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rba:RB9386 probable FixW protein YP_001327534.1 KEGG: sme:SMb20920 hypothetical secreted protein YP_001327536.1 KEGG: sme:SMb20518 hypothetical protein YP_001327537.1 KEGG: sme:SMb21395 hypothetical protein YP_001327540.1 KEGG: pen:PSEEN4173 hypothetical protein YP_001327541.1 KEGG: pae:PA0643 hypothetical protein YP_001327543.1 KEGG: rsp:RSP_2990 hypothetical protein YP_001327544.1 KEGG: aba:Acid345_3157 hypothetical protein YP_001327549.1 KEGG: mes:Meso_1231 hypothetical protein YP_001327551.1 KEGG: mes:Meso_1230 hypothetical protein YP_001327552.1 KEGG: mes:Meso_1229 hypothetical protein YP_001327553.1 KEGG: mes:Meso_1228 hypothetical protein YP_001327554.1 KEGG: mes:Meso_1226 hypothetical protein YP_001327555.1 KEGG: mes:Meso_1224 hypothetical protein YP_001327556.1 KEGG: mes:Meso_1223 hypothetical protein YP_001327558.1 similar to Y20302; KEGG: sme:SMb21028 conserved hypothetical protein, similar to Y20302 YP_001327559.1 KEGG: mes:Meso_1220 hypothetical protein YP_001327560.1 KEGG: mlo:mlr8010 hypothetical protein YP_001327561.1 KEGG: mlo:mlr8009 hypothetical protein YP_001327562.1 KEGG: mlo:mlr8007 hypothetical protein YP_001327563.1 KEGG: mlo:mlr8006 hypothetical protein YP_001327564.1 TIGRFAM: phage-associated protein, HI1409 family; KEGG: mlo:mlr8004 hypothetical protein YP_001327565.1 PFAM: protein of unknown function DUF264; KEGG: gox:GOX2457 phage DNA Packaging protein YP_001327566.1 KEGG: gox:GOX2458 phage terminase small subunit YP_001327572.1 TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine-binding; KEGG: bhe:BH05360 acyl carrier protein YP_001327573.1 KEGG: sme:SMb20548 hypothetical protein YP_001327574.1 PFAM: GcrA cell cycle regulator YP_001327577.1 PFAM: protein of unknown function DUF1064; KEGG: lin:lin0099 hypothetical protein YP_001327580.1 KEGG: rpb:RPB_0521 hypothetical protein YP_001327581.1 PFAM: protein of unknown function DUF982; KEGG: sme:SMb20546 hypothetical protein YP_001327583.1 KEGG: nar:Saro_2694 hypothetical protein YP_001327584.1 KEGG: mes:Meso_0214 hypothetical protein YP_001327585.1 KEGG: sme:SMc04009 hypothetical protein YP_001327586.1 KEGG: nha:Nham_2404 hypothetical protein YP_001327587.1 PFAM: peptidase S24 S26A and S26B; KEGG: mlo:mll8500 repressor protein C YP_001327589.1 KEGG: mlo:mll7982 hypothetical protein YP_001327590.1 PFAM: phage Gp37Gp68 family protein; KEGG: mlo:mlr7981 ABC transporter, ATP-binding protein YP_001327593.1 PFAM: siphovirus Gp157 family protein; KEGG: mlo:mll7978 hypothetical protein YP_001327594.1 TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: mlo:mll7977 hypothetical protein YP_001327595.1 KEGG: sit:TM1040_0782 hypothetical protein YP_001327597.1 PFAM: protein of unknown function DUF1643; KEGG: sme:SMb20554 hypothetical protein YP_001327600.1 KEGG: mag:amb2709 integrase YP_001327601.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sme:SMc04271 hypothetical protein YP_001327602.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc04272 hypothetical protein YP_001327603.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMc04274 hypothetical protein YP_001327604.1 KEGG: sme:SMc04276 hypothetical signal peptide protein YP_001327606.1 KEGG: sme:SMc04280 hypothetical signal peptide protein YP_001327607.1 KEGG: sme:SMc04280 hypothetical signal peptide protein YP_001327608.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMc04283 putative transmembrane protein YP_001327609.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMc04287 hypothetical protein YP_001327610.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMc04289 hypothetical protein YP_001327611.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc04292 probable adenylate/guanylate cyclase protein YP_001327612.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001327613.1 KEGG: sme:SMc04298 hypothetical protein YP_001327614.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: sme:SMc04299 hypothetical protein YP_001327615.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc04300 probable ferric iron transport ATP-binding protein YP_001327616.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04316 probable ferric iron transport system permease protein YP_001327617.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc04317 iron-binding periplasmic protein YP_001327618.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMc04318 cold shock transcription regulator protein YP_001327619.1 KEGG: sme:SMc04319 hypothetical protein YP_001327620.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001327621.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: rle:RL1309 putative transmembrane protein YP_001327622.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc04321 putative glutathione S-transferase protein YP_001327623.1 PFAM: aldo/keto reductase; KEGG: sme:SMc04322 putative oxidoreductase protein YP_001327624.1 PFAM: aminotransferase class I and II; KEGG: sme:SMc04323 probable aminotransferase protein YP_001327625.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ret:RHE_CH02733 probable SAM-dependent methyltransferase protein YP_001327626.1 KEGG: sme:SMc04324 hypothetical protein YP_001327627.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc04338 hypothetical protein YP_001327628.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc04341 putative amino acid-binding periplasmic protein YP_001327629.1 KEGG: sme:SMc04343 putative adenylate/guanylate cyclase transmembrane protein YP_001327630.1 KEGG: sme:SMc04344 hypothetical signal peptide protein YP_001327631.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001327632.1 PFAM: regulatory protein TetR; KEGG: sme:SMc04348 putative transcription regulator protein YP_001327633.1 PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: sme:SMc04352 conserved hypothetical signal peptide protein YP_001327634.1 KEGG: sme:SMc04357 putative glycine-rich protein YP_001327635.1 KEGG: sme:SMc04359 putative transmembrane protein YP_001327636.1 PFAM: aminoglycoside phosphotransferase; KEGG: sme:SMc04360 hypothetical protein YP_001327637.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: sme:SMc04452 putative NADH dehydrogenase transmembrane protein YP_001327638.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc01403 putative transcription regulator protein YP_001327639.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: sme:SMc01404 putative aspartate racemase protein YP_001327640.1 PFAM: helix-turn-helix HxlR type; KEGG: sme:SMc01493 hypothetical protein YP_001327641.1 PFAM: dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: sme:SMc01405 hypothetical protein YP_001327642.1 PFAM: protein of unknown function DUF983; KEGG: rle:RL1423 putative transmembrane protein YP_001327643.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMc01406 putative transcription regulator protein YP_001327644.1 KEGG: sme:SMb20473 hypothetical protein YP_001327645.1 PFAM: Carbamoyltransferase; KEGG: sme:SMb20472 putative nodulation protein YP_001327646.1 KEGG: sme:SMb20471 hypothetical protein YP_001327647.1 KEGG: sme:SMb20470 hypothetical protein YP_001327648.1 KEGG: sme:SMb20469 hypothetical protein YP_001327649.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMb20468 putative sensory transduction DNA-binding response regulator protein YP_001327650.1 PFAM: acyltransferase 3; KEGG: hch:HCH_02732 predicted acyltransferase YP_001327651.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001327652.1 PFAM: protein of unknown function DUF899 thioredoxin family protein; KEGG: sme:SMc01408 hypothetical protein YP_001327653.1 KEGG: sme:SMc01409 hypothetical protein YP_001327654.1 PFAM: 17 kDa surface antigen; KEGG: sme:SMc01410 putative lipoprotein transmembrane YP_001327655.1 KEGG: sme:SMc01489 hypothetical signal peptide protein YP_001327656.1 KEGG: sme:SMc01490 hypothetical protein YP_001327657.1 KEGG: sme:SMc01411 hypothetical protein YP_001327658.1 PFAM: TfuA domain protein core; KEGG: sme:SMc01412 hypothetical protein YP_001327659.1 PFAM: protein of unknown function DUF181; KEGG: sme:SMc01413 hypothetical protein YP_001327660.1 SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc01491 conserved hypothetical protein YP_001327662.1 KEGG: sme:SMc01492 probable suppressor of E.coli rpoH thermosensitive mutation transmembrane protein YP_001327663.1 KEGG: sme:SMc01414 exodeoxyribonuclease V YP_001327664.1 PFAM: putative ammonia monooxygenase; KEGG: sme:SMc01415 putative transmembrane protein YP_001327665.1 PFAM: Secreted repeat of unknown function; KEGG: sme:SMc01418 hypothetical signal peptide protein YP_001327666.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein YP_001327667.1 KEGG: sme:SMc01420 hypothetical protein YP_001327668.1 PFAM: nitrile hydratase beta subunit; KEGG: sme:SMc01423 probable nitrile hydratase subunit beta protein YP_001327669.1 TIGRFAM: nitrile hydratase, alpha subunit; PFAM: Nitrile hydratase alpha chain; KEGG: sme:SMc01424 probable nitrile hydratase subunit alpha protein YP_001327670.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc01425 hypothetical protein YP_001327671.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc01426 hypothetical protein YP_001327672.1 KEGG: sme:SMc01427 hypothetical protein YP_001327673.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMc01428 probable cold shock transcription regulator protein YP_001327674.1 PFAM: aldo/keto reductase; KEGG: sme:SMc01429 putative oxidoreductase protein YP_001327675.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001327676.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sme:SMc01431 acetolactate synthase large subunit YP_001327677.1 PFAM: protein of unknown function DUF87; KEGG: sme:SMc01432 hypothetical protein YP_001327678.1 KEGG: sme:SMc01433 hypothetical protein YP_001327679.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001327680.1 TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc01494 putative phosphoserine phosphatase protein YP_001327681.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01437 putative acetyl transferase protein YP_001327682.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sme:SMc01438 putative protease precursor signal peptide protein YP_001327683.1 PFAM: amino acid-binding ACT domain protein; KEGG: sme:SMc01439 hypothetical protein YP_001327684.1 KEGG: mlo:msl1453 hypothetical protein YP_001327685.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: sme:SMc01440 putative hydrolase serine protease transmembrane protein YP_001327686.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: sme:SMc01441 putative membrane bound protease protein YP_001327687.1 PFAM: dihydrofolate reductase region; KEGG: sme:SMc01442 probable dihydrofolate reductase protein YP_001327688.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc01443 putative glutathione S-transferase protein YP_001327689.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001327690.1 KEGG: sme:SMc01445 hypothetical protein YP_001327691.1 KEGG: sme:SMc01446 hypothetical protein YP_001327692.1 KEGG: sme:SMc01447 hypothetical protein YP_001327694.1 KEGG: sme:SMc01449 hypothetical protein YP_001327695.1 PFAM: protein of unknown function DUF1321; KEGG: sme:SMc01450 hypothetical protein YP_001327696.1 KEGG: sme:SMc01451 hypothetical protein YP_001327697.1 KEGG: sme:SMc01452 hypothetical protein YP_001327698.1 KEGG: sme:SMc01454 hypothetical protein YP_001327699.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc01455 putative D-lactate dehydrogenase (cytochrome) protein YP_001327700.1 PFAM: Protein of unknown function DUF1772; KEGG: sme:SMc01456 hypothetical protein YP_001327701.1 PFAM: acriflavin resistance protein; KEGG: sme:SMc01457 putative transport transmembrane protein YP_001327702.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc01458 putative transport protein YP_001327703.1 PFAM: cyclase family protein; KEGG: sme:SMc01459 hypothetical transmembrane protein YP_001327704.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sme:SMc01460 hypothetical protein YP_001327705.1 PFAM: UvrD/REP helicase; KEGG: sme:SMc01461 probable DNA helicase II protein YP_001327706.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; homoserine dehydrogenase NAD-binding; KEGG: jan:Jann_1468 oxidoreductase-like YP_001327707.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: mlo:mll7360 hypothetical protein YP_001327708.1 KEGG: mlo:mll4958 hypothetical protein YP_001327709.1 KEGG: mlo:mll7366 ABC transporter binding protein YP_001327710.1 PFAM: inner-membrane translocator; KEGG: mlo:mll7365 ABC transporter permease protein YP_001327711.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mlo:mll7362 ABC sugar transport ATP binding protein YP_001327712.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01462 putative acetyltransferase protein YP_001327713.1 PFAM: phosphoribosyltransferase; KEGG: sme:SMc01463 hypothetical protein YP_001327714.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMc01464 hypothetical protein YP_001327715.1 PFAM: CreA family protein; KEGG: sme:SMc01465 putative CREA protein YP_001327716.1 KEGG: sme:SMc01467 hypothetical signal peptide protein YP_001327717.1 KEGG: sme:SMc01467 hypothetical signal peptide protein YP_001327718.1 PFAM: CheW domain protein; KEGG: sme:SMc01468 probable chemotaxis protein YP_001327719.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sme:SMc01469 probable methyl accepting chemotaxis transmembrane protein YP_001327720.1 KEGG: sme:SMc01470 hypothetical signal peptide protein YP_001327721.1 PFAM: electron transport protein SCO1/SenC; KEGG: sme:SMc01471 putative cytochrome c oxidase assembly factor transmembrane protein YP_001327722.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001327723.1 PFAM: creatinase; peptidase M24; KEGG: sme:SMc01885 putative aminopeptidase P protein YP_001327724.1 KEGG: sme:SMc01884 hypothetical signal peptide protein YP_001327725.1 PFAM: branched-chain amino acid transport; KEGG: sme:SMc01883 hypothetical protein YP_001327726.1 PFAM: AzlC family protein; KEGG: sme:SMc01882 hypothetical protein YP_001327727.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001327728.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001327729.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01879 hypothetical protein YP_001327730.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL120007 putative permease component of ABC transporter YP_001327731.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mll0851 putative multiple sugar transport system permease protein YP_001327732.1 PFAM: extracellular solute-binding protein family 1; KEGG: bch:Bcen2424_4775 extracellular solute-binding protein, family 1 YP_001327733.1 PFAM: sulfatase; KEGG: sus:Acid_1528 sulfatase YP_001327734.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rpa:RPA3471 ABC transporter, ATP-binding protein YP_001327735.1 KEGG: rle:RL1496 putative sugar isomerase family protein YP_001327736.1 PFAM: sulfatase; KEGG: stm:STM0886 putative sulfatase YP_001327737.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: xcb:XC_2486 galactose-binding protein regulator YP_001327738.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001327739.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: sme:SMc01877 probable DNA repair protein YP_001327740.1 KEGG: sme:SMc01876 hypothetical transmembrane protein YP_001327741.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001327742.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001327743.1 PFAM: cell division protein FtsA; KEGG: sme:SMc01873 cell division protein YP_001327744.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein FtsQ-type; KEGG: sme:SMc01872 cell division transmembrane protein YP_001327745.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001327746.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001327747.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sme:SMc01869 putative transport transmembrane protein YP_001327748.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001327749.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001327750.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001327751.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: sme:SMc01865 probable cell division protein FTSW peptidoglycan synthesis YP_001327752.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001327753.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001327754.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sme:SMc01862 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_001327755.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001327756.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sme:SMc01860 probable penicillin-binding transmembrane protein YP_001327757.1 KEGG: sme:SMc01859 hypothetical protein YP_001327758.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: sme:SMc01858 S-adenosyl-methyltransferase YP_001327759.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001327760.1 catalyzes the formation of pyruvate from serine YP_001327761.1 catalyzes the oxidative deamination of D-amino acids YP_001327762.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001327763.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: pde:Pden_4905 methenyltetrahydrofolate cyclohydrolase YP_001327764.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: mag:amb2339 glycine/serine hydroxymethyltransferase YP_001327765.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pol:Bpro_4368 transcriptional regulator, LysR family YP_001327766.1 PFAM: extracellular solute-binding protein family 3; KEGG: bja:bll2909 probable amino acid binding protein YP_001327767.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: hch:HCH_05808 ABC-type amino acid transport system, permease component YP_001327768.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ana:alr4166 polar amino acid transport system permease protein YP_001327769.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: maq:Maqu_3047 ABC transporter related YP_001327770.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc01856 putative sarcosine oxidase protein YP_001327771.1 PFAM: Lytic transglycosylase catalytic; KEGG: sme:SMc01855 hypothetical protein YP_001327772.1 PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sme:SMc01854 N-acetylmuramoyl-L-alanine amidase YP_001327773.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sme:SMc01853 DnaJ-like protein YP_001327774.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate YP_001327775.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc01851 putative amino acid efflux protein YP_001327776.1 PFAM: Lytic transglycosylase catalytic; KEGG: sme:SMc01850 hypothetical protein YP_001327777.1 PFAM: beta-lactamase; KEGG: sme:SMc01849 putative hydrolase transmembrane protein YP_001327778.1 KEGG: sme:SMc01848 hypothetical protein YP_001327779.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc01847 putative methyltransferase protein YP_001327780.1 PFAM: glycoside hydrolase family 25; KEGG: sme:SMc01846 putative hydrolase glycosidase protein YP_001327781.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMc01845 putative transglycosylase transmembrane protein YP_001327782.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc01844 hypothetical protein YP_001327783.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: sme:SMc01843 probable 5,10-methylenetetrahydrofolate reductase oxidoreductase protein YP_001327784.1 PFAM: regulatory protein ArsR; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc01842 putative methyltransferase transcription regulator protein YP_001327785.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001327786.1 KEGG: sme:SMc02819 putative ribonuclease protein YP_001327787.1 KEGG: sme:SMc02818 hypothetical protein YP_001327788.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc02817 hypothetical protein YP_001327789.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_001327790.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001327791.1 PFAM: protein of unknown function DUF442; KEGG: sme:SMc01573 hypothetical protein YP_001327792.1 KEGG: sme:SMc01574 hypothetical protein YP_001327793.1 PFAM: Peptidoglycan-binding domain 1 protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc01575 hypothetical protein YP_001327794.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc01576 putative oxidoreductase protein YP_001327795.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc01579 hypothetical protein YP_001327796.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sme:SMc01582 putative alcohol dehydrogenase protein YP_001327797.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc01588 putative aldehyde dehydrogenase protein YP_001327798.1 PFAM: glutamine synthetase catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase YP_001327799.1 PFAM: amino acid permease-associated region; KEGG: sme:SMc01597 putative amino-acid permease protein YP_001327800.1 PFAM: N-formylglutamate amidohydrolase; KEGG: sme:SMc01600 hypothetical protein YP_001327801.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMc01602 hypothetical protein YP_001327802.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01605 putative periplasmic binding ABC transporter protein YP_001327803.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01606 putative permease protein YP_001327804.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01607 putative permease protein YP_001327805.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01608 putative ATP-binding ABC transporter protein YP_001327806.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001327807.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMc01610 putative transcription regulator protein YP_001327808.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sme:SMc01611 putative ferrichrome-iron receptor precursor protein YP_001327809.1 PFAM: creatinase; peptidase M24; KEGG: bms:BR1062 proline dipeptidase YP_001327810.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rle:pRL100267 putative ATP-binding component of ABC transporter YP_001327811.1 PFAM: protein of unknown function DUF1680; KEGG: rle:pRL100266 hypothetical protein YP_001327812.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL100265 putative permease component of ABC transporter YP_001327813.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:pRL100264 putative permease component of ABC transporter YP_001327814.1 PFAM: extracellular solute-binding protein family 1; KEGG: rle:pRL100263 putative substrate-binding component of ABC transporter YP_001327815.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rle:pRL100262 putative transcriptional regulator YP_001327816.1 KEGG: sme:SMa0370 hypothetical protein YP_001327817.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001327818.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001327819.1 PFAM: regulatory protein DeoR; regulatory protein ArsR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: sme:SMc01615 putative transcription regulator protein YP_001327820.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc01616 putative D-erythrulose-1-phosphate dehydrogenase protein YP_001327821.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc01617 hypothetical protein YP_001327822.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc01618 putative carbohydrate kinase protein YP_001327823.1 PFAM: class II aldolase/adducin family protein; KEGG: sme:SMc01619 hypothetical protein YP_001327824.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001327825.1 PFAM: class II aldolase/adducin family protein; KEGG: sme:SMc01621 putative L-fuculose phosphate aldolase protein YP_001327826.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc01622 putative phosphoglycerate dehydrogenase YP_001327827.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc01623 putative erythritol kinase protein YP_001327828.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01624 putative ABC transporter ATP-binding protein YP_001327829.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01625 putative ABC transporter ATP-binding protein YP_001327830.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01626 putative permease ABC transporter protein YP_001327831.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01627 putative permease ABC transporter protein YP_001327832.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01628 putative periplasmic binding ABC transporter protein YP_001327833.1 PFAM: putative sugar-binding domain protein; KEGG: sme:SMc01629 putative ery operon repressor transcription regulator protein YP_001327834.1 PFAM: regulatory protein LuxR; KEGG: sme:SMc01630 putative transcription regulator protein YP_001327835.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01631 probable ATP-binding ABC transporter protein YP_001327836.1 KEGG: sme:SMc01632 putative periplasmic binding ABC transporter protein YP_001327837.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01633 putative permease ABC transporter protein YP_001327838.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01634 putative permease ABC transporter protein YP_001327839.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc01635 putative oxidoreductase protein YP_001327840.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sme:SMc01636 putative transcription regulator protein YP_001327841.1 PFAM: protein of unknown function DUF849; KEGG: sme:SMc01637 hypothetical protein YP_001327842.1 Converts (S)-3-hydroxyacyl-CoA to 3-oxyacyl-CoA; may also act as a thioesterase YP_001327843.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sme:SMc01639 putative acyl-CoA dehydrogenase protein YP_001327844.1 PFAM: CoA-binding domain protein; KEGG: sme:SMc01640 putative acyl-CoA synthetase protein YP_001327845.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001327846.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc01642 putative periplasmic binding protein YP_001327847.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01643 putative permease ABC transporter protein YP_001327848.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01644 putative permease ABC transporter protein YP_001327849.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01645 putative ABC transporter ATP-binding protein YP_001327850.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMc01646 hypothetical protein YP_001327851.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc01647 putative periplasmic binding protein YP_001327852.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase domain protein; KEGG: sme:SMc01648 hypothetical protein YP_001327853.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: sme:SMc01650 putative esterase/lipase protein YP_001327854.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01651 putative transcription regulator protein YP_001327855.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01652 putative ABC transporter protein YP_001327856.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01653 putative ATP-binding ABC transporter protein YP_001327857.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01654 putative permease ABC transporter protein YP_001327858.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01655 putative permease ABC transporter protein YP_001327859.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001327860.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sme:SMc01657 putative ferrichrome-iron receptor precursor protein YP_001327861.1 PFAM: ferric iron reductase; KEGG: sme:SMc01658 putative transport protein YP_001327862.1 PFAM: periplasmic binding protein; KEGG: sme:SMc01659 putative transport transmembrane protein YP_001327863.1 KEGG: sme:SMc01660 hypothetical protein YP_001327864.1 PFAM: trimethylamine methyltransferase; KEGG: sme:SMc01661 putative methyltransferase protein YP_001327865.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc01662 putative sarcosine dehydrogenase YP_001327866.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc01663 putative dimethylglycine dehydrogenase precursor YP_001327867.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01664 putative transcription regulator protein YP_001327868.1 KEGG: sme:SMc01665 hypothetical protein YP_001327869.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_001327870.1 SMART: helix-turn-helix domain protein; KEGG: rru:Rru_A3065 transcriptional regulator, XRE family YP_001327871.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01667 hypothetical protein YP_001327872.1 PFAM: regulatory protein TetR; KEGG: sme:SMc01668 putative transcription regulator protein YP_001327873.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001327874.1 KEGG: sme:SMc01670 hypothetical transmembrane protein YP_001327875.1 KEGG: sme:SMc01671 hypothetical protein YP_001327876.1 PFAM: protein of unknown function DUF1194; KEGG: ret:RHE_CH02690 hypothetical protein YP_001327877.1 KEGG: sme:SMc01540 hypothetical protein YP_001327878.1 PFAM: protein of unknown function DUF181; KEGG: sme:SMc01541 hypothetical protein YP_001327879.1 KEGG: sme:SMc01542 hypothetical protein YP_001327880.1 KEGG: sme:SMc01543 hypothetical protein YP_001327881.1 PFAM: aminoglycoside 3-N-acetyltransferase; KEGG: sme:SMc02813 probable aminoglycoside N3'-acetyltransferase protein YP_001327882.1 PFAM: helix-turn-helix domain protein; KEGG: atu:Atu5113 transcriptional regulator YP_001327883.1 PFAM: protein of unknown function DUF541; KEGG: sme:SMc01556 hypothetical protein YP_001327884.1 KEGG: sme:SMc01557 hypothetical signal peptide protein YP_001327885.1 PFAM: protein of unknown function DUF1486; KEGG: sme:SMc01558 hypothetical protein YP_001327886.1 PFAM: protein of unknown function UPF0047; KEGG: sme:SMc01559 hypothetical protein YP_001327887.1 PFAM: protein of unknown function DUF1428; KEGG: sme:SMc01560 hypothetical protein YP_001327888.1 KEGG: sme:SMc01561 putative transmembrane protein YP_001327889.1 PFAM: GYD family protein; KEGG: sme:SMc01562 hypothetical protein YP_001327890.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001327891.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001327892.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001327893.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc01566 probable ATP-dependent DNA helicase protein YP_001327894.1 synthesizes RNA primers at the replication forks YP_001327895.1 PFAM: GatB/Yqey domain protein; KEGG: sme:SMc01568 hypothetical protein YP_001327896.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001327897.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01570 putative transcription regulator protein YP_001327898.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc01571 putative oxidoreductase protein YP_001327899.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: sme:SMc01572 putative oxidoreductase protein YP_001327900.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001327901.1 KEGG: sme:SMc01580 hypothetical protein YP_001327902.1 KEGG: sme:SMc01581 hypothetical protein YP_001327903.1 PFAM: glucose sorbosone dehydrogenase; KEGG: sme:SMc01583 hypothetical protein YP_001327904.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc01584 hypothetical protein YP_001327905.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sme:SMc01585 putative cold shock transcription regulator protein YP_001327906.1 KEGG: sme:SMc01586 hypothetical protein YP_001327907.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc01587 hypothetical protein YP_001327908.1 KEGG: sme:SMc01589 hypothetical protein YP_001327909.1 PFAM: protein of unknown function DUF1236; SH3 type 3 domain protein; KEGG: sme:SMc01590 hypothetical protein YP_001327910.1 KEGG: sme:SMc01591 hypothetical protein YP_001327911.1 PFAM: regulatory protein MarR; KEGG: sme:SMc01592 putative transcription regulator protein YP_001327912.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc01593 putative transcription regulator protein YP_001327913.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc01595 putative sensor histidine kinase transmembrane protein YP_001327914.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: sme:SMc04456 putative chaperone protein YP_001327915.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pae:PA3124 probable transcriptional regulator YP_001327916.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001327917.1 PFAM: Protein of unknown function DUF1790; KEGG: sme:SMc02678 hypothetical protein YP_001327918.1 PFAM: protein of unknown function DUF526; KEGG: sme:SMc03744 hypothetical protein YP_001327919.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001327920.1 PFAM: protein of unknown function DUF185; KEGG: sme:SMc02682 hypothetical protein YP_001327921.1 PFAM: protein of unknown function DUF152; KEGG: sme:SMc02683 conserved hypothetical protein YP_001327922.1 PFAM: creatinase; peptidase M24; KEGG: sme:SMc02684 putative hydrolase/peptidase protein YP_001327923.1 KEGG: sme:SMc02685 hypothetical protein YP_001327924.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001327925.1 KEGG: sme:SMc02687 hypothetical protein YP_001327926.1 PFAM: protein of unknown function DUF779; KEGG: sme:SMc02688 hypothetical protein YP_001327927.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc02689 probable aldehyde dehydrogenase protein YP_001327928.1 PFAM: helix-turn-helix Fis-type; GAF domain protein; KEGG: sme:SMc02690 hypothetical protein YP_001327929.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; KEGG: sme:SMc02691 putative membrane transport protein YP_001327930.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001327931.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001327932.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001327933.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001327934.1 KEGG: ret:RHE_CH03032 hypothetical protein YP_001327935.1 PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc02696 hypothetical protein YP_001327936.1 PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc02697 hypothetical protein YP_001327937.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001327938.1 KEGG: sme:SMc02699 hypothetical protein YP_001327939.1 PFAM: Polynucleotide adenylyltransferase region; KEGG: sme:SMc02700 tRNA nucleotidyltransferase (CCA-adding enzyme) YP_001327940.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc02701 hypothetical protein YP_001327941.1 PFAM: protein of unknown function DUF1285; KEGG: sme:SMc02702 hypothetical protein YP_001327942.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sme:SMc02703 methanol dehydrogenase regulatory protein YP_001327943.1 PFAM: protein of unknown function DUF58; KEGG: sme:SMc02704 hypothetical protein YP_001327944.1 TIGRFAM: conserved hypothetical membrane protein; KEGG: sme:SMc02705 hypothetical protein YP_001327945.1 KEGG: sme:SMc02706 hypothetical protein YP_001327946.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01545 hypothetical protein YP_001327947.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02707 hypothetical protein YP_001327948.1 KEGG: sme:SMc02708 putative glutathione S-transferase YP_001327949.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc02711 hypothetical protein YP_001327950.1 PFAM: metallophosphoesterase; KEGG: sme:SMc02712 hypothetical protein YP_001327951.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc02713 putative RNA polymerase sigma-E factor (sigma-24) protein YP_001327952.1 KEGG: sme:SMc02714 hypothetical protein YP_001327953.1 PFAM: Rv0623 family protein transcription factor; KEGG: sme:SMc02716 conserved hypothetical protein YP_001327954.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: sme:SMc02717 2-isopropylmalate synthase YP_001327955.1 KEGG: sme:SMc02718 hypothetical/unknown protein YP_001327956.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001327957.1 PFAM: HupE/UreJ protein; KEGG: atc:AGR_C_4126 hupe protein precursor YP_001327958.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rle:RL2080 putative acetyltransferase YP_001327959.1 PFAM: aminoglycoside phosphotransferase; KEGG: sme:SMc02722 putative aminoglycoside 3'-phosphotransferase protein YP_001327960.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001327961.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: sme:SMc02724 hypothetical protein YP_001327962.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II YP_001327963.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sme:SMc02726 putative iron transport protein YP_001327964.1 PFAM: Extensin family protein; KEGG: sme:SMc02727 hypothetical protein YP_001327965.2 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001327966.1 KEGG: sme:SMc02729 hypothetical protein YP_001327967.1 KEGG: sme:SMc02730 hypothetical protein YP_001327968.1 PFAM: protein of unknown function DUF559; KEGG: sme:SMc02732 hypothetical protein YP_001327969.1 KEGG: sme:SMc02733 hypothetical protein YP_001327970.1 KEGG: sme:SMc02734 hypothetical protein YP_001327971.1 KEGG: sme:SMc02735 hypothetical protein YP_001327972.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02737 putative glycine betaine-binding ABC transporter protein YP_001327973.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02738 putative glycine betaine transport system permease ABC transporter protein YP_001327974.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02739 putative glycine betaine transport ATP-binding ABC transporter protein YP_001327975.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: sme:SMc04457 hypothetical protein YP_001327976.1 PFAM: regulatory protein ArsR; KEGG: ret:RHE_CH03089 transcriptional regulator protein (repressor of nodulation genes), ArsR family YP_001327977.1 KEGG: sme:SMc01535 hypothetical protein YP_001327978.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMb20235 putative sugar ABC transporter ATP-binding protein YP_001327979.1 KEGG: sme:SMb20234 hypothetical protein YP_001327980.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20233 putative sugar ABC transporter permease protein YP_001327981.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20232 putative suagr ABC transporter permease protein YP_001327982.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb20231 putative ABC transporter sugar-binding protein YP_001327983.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20230 probable smc22-r protein YP_001327984.1 catalyze the conversion of beta amino acids to the corresponding beta keto acid with pyruvate as the amine acceptor YP_001327985.1 TIGRFAM: adenine deaminase; PFAM: amidohydrolase; KEGG: sme:SMc01533 putative adenine deaminase protein YP_001327986.1 TIGRFAM: addiction module antidote protein, HigA family; KEGG: bhe:BH06620 virulence-associated protein YP_001327987.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMc01532 putative alpha-glycosylase protein YP_001327988.1 PFAM: PfkB domain protein; KEGG: sme:SMc01531 putative 2-dehydro-3-deoxygluconokinase protein YP_001327989.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01529 putative dipeptide transport ATP-binding ABC transporter protein YP_001327990.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01528 putative dipeptide transport ATP-binding ABC transporter protein YP_001327991.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01527 putative dipeptide transport system permease ABC transporter protein YP_001327992.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01526 putative dipeptide transport system permease ABC transporter protein YP_001327993.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc01525 putative dipeptide binding periplasmic protein YP_001327994.1 PFAM: peptidase M19 renal dipeptidase; KEGG: sme:SMc01524 putative dipeptidase protein YP_001327995.1 PFAM: small multidrug resistance protein; KEGG: sme:SMc01523 putative methyl viologen/ethidium resistance transmembrane protein YP_001327996.1 PFAM: regulatory protein TetR; KEGG: sme:SMc01522 hypothetical protein YP_001327997.1 PFAM: globin; KEGG: sme:SMc01520 hypothetical protein YP_001327998.1 PFAM: protein of unknown function DUF423; KEGG: sme:SMc01519 hypothetical protein YP_001327999.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sme:SMc01518 hypothetical protein YP_001328000.1 KEGG: sme:SMc01517 hypothetical protein YP_001328001.1 KEGG: sme:SMc01516 hypothetical protein YP_001328002.1 TIGRFAM: TonB family protein; KEGG: sme:SMc01515 TonB protein YP_001328003.1 KEGG: sme:SMc01514 hypothetical protein YP_001328004.1 KEGG: sme:SMc01747 hypothetical protein YP_001328005.1 PFAM: Haemin-degrading family protein; KEGG: sme:SMc01513 putative hemin transport protein YP_001328006.1 PFAM: periplasmic binding protein; KEGG: sme:SMc01512 putative hemin binding periplasmic transmembrane protein YP_001328007.1 PFAM: transport system permease protein; KEGG: sme:SMc01511 putative hemin transport system permease transmembrane protein YP_001328008.1 with HmuTU is involved in the transport of hemin YP_001328009.1 KEGG: sme:SMc01509 hypothetical protein YP_001328010.1 KEGG: sme:SMc01508 hypothetical protein YP_001328011.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; HWE histidine kinase; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc01507 hypothetical protein YP_001328012.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001328013.1 KEGG: sme:SMc01505 hypothetical protein YP_001328014.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_001328015.1 KEGG: sus:Acid_3306 hypothetical protein YP_001328016.1 KEGG: rle:pRL120547 putative MFS family transporter protein YP_001328017.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rle:pRL120548 putative LysR family transcriptional regulator YP_001328018.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc01503 putative sugar kinase protein YP_001328019.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sme:SMc01502 putative hydrolase phosphatase protein YP_001328020.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sme:SMc01501 probable mannitol 2-dehydrogenase protein YP_001328021.1 Converts D-sorbitol to L-sorbose YP_001328022.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01499 probable ATP-binding transport ABC transporter protein YP_001328023.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01498 probable sorbitol/mannitol transport inner membrane protein YP_001328024.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01497 probable sorbitol/mannitol transport inner membrane transmembrane protein YP_001328025.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01496 probable sorbitol-binding periplasmic protein YP_001328026.1 PFAM: putative sugar-binding domain protein; KEGG: sme:SMc01495 probable transcription regulator protein YP_001328027.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001328028.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001328029.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc01816 putative oxidoreductase protein YP_001328030.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01817 putative transcription regulator protein YP_001328031.1 PFAM: ferredoxin; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc01818 putative adenylate cyclase transmembrane protein YP_001328032.1 PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: sme:SMc01819 putative transcription regulator protein YP_001328033.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001328034.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001328035.1 PFAM: Cupin domain protein; Cupin 2 conserved barrel domain protein; KEGG: sme:SMc01822 hypothetical protein YP_001328036.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01823 putative ATP-binding ABC transporter protein YP_001328037.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc01824 hypothetical protein YP_001328038.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01825 putative permease ABC transporter protein YP_001328039.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01826 putative permease ABC transporter protein YP_001328040.1 PFAM: NMT1/THI5 like domain protein; KEGG: sme:SMc01827 hypothetical protein YP_001328041.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc01828 putative transport transmembrane protein YP_001328042.1 PFAM: acriflavin resistance protein; KEGG: sme:SMc01829 putative transport transmembrane protein YP_001328043.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: sme:SMa1207 FixK-like regulatory protein YP_001328044.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: sme:SMc01830 probable urease accessory protein YP_001328045.1 PFAM: Urease accessory protein UreF; KEGG: sme:SMc01831 putative urease accessory protein YP_001328046.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_001328047.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sme:SMc01833 hypothetical protein YP_001328048.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMc01834 hypothetical protein YP_001328049.1 KEGG: ret:RHE_CH03304 probable urease-associated protein YP_001328050.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001328051.1 KEGG: sme:SMc01838 putative urease accessory protein YP_001328052.1 PFAM: protein of unknown function DUF1311; KEGG: sme:SMc02046 hypothetical protein YP_001328053.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001328054.1 PFAM: protein of unknown function DUF1272; KEGG: sme:SMc01940 hypothetical protein YP_001328055.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001328056.1 PFAM: Urease accessory protein UreD; KEGG: sme:SMc01942 probable urease accessory protein YP_001328057.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc01943 2-hydroxyacid dehydrogenase YP_001328058.1 PFAM: Peptidase A1 pepsin; KEGG: dme:Dmel_CG33128 CG33128 YP_001328059.1 PFAM: Extracellular ligand-binding receptor; KEGG: sme:SMc01946 putative leucine-specific binding protein precursor YP_001328060.1 KEGG: sme:SMc01947 hypothetical protein YP_001328061.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01948 probable high-affinity branched-chain amino acid transport ATP-binding ABC transporter protein YP_001328062.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01949 probable high-affinity branched-chain amino acid transport ATP-binding ABC transporter protein YP_001328063.1 PFAM: inner-membrane translocator; KEGG: sme:SMc01950 probable high-affinity branched-chain amino acid transport permease ABC transporter protein YP_001328064.1 PFAM: inner-membrane translocator; KEGG: sme:SMc01951 probable high-affinity branched-chain amino acid transport permease ABC transporter protein YP_001328065.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: sme:SMc01952 putative transmembrane protein YP_001328066.1 KEGG: sme:SMc01953 putative 2-component receiver domain protein YP_001328067.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: sme:SMc01954 putative transcription regulator protein YP_001328068.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc01955 putative oxidoreductase protein YP_001328069.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01956 hypothetical protein YP_001328070.1 PFAM: NADPH-dependent FMN reductase; KEGG: sme:SMc01960 putative oxidoreductase protein YP_001328071.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01961 hypothetical protein YP_001328072.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sme:SMc01962 hypothetical protein YP_001328073.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01963 putative spermidine/putrescine transport system permease ABC transporter protein YP_001328074.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01964 putative spermidine/putrescine transport system permease ABC transporter protein YP_001328075.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01965 putative spermidine/putrescine transport ATP-binding ABC transporter protein YP_001328076.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01966 putative spermidine/putrescine-binding periplasmic ABC transporter protein YP_001328077.1 TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sme:SMc01967 putative agmatinase protein YP_001328078.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc01968 putative transcription regulator protein YP_001328079.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sme:SMc01969 hypothetical protein YP_001328080.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc01970 hypothetical protein YP_001328081.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc01971 putative aldehyde dehydrogenase protein YP_001328082.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc01972 putative oxidoreductase protein YP_001328083.1 PFAM: glutamine synthetase catalytic region; KEGG: sme:SMc01973 putative homologous to A glutamine synthetase protein YP_001328084.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc01974 putative transcription regulator protein YP_001328085.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc01975 putative transcription regulator protein YP_001328086.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc01976 hypothetical protein YP_001328087.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc01977 putative sugar-binding periplasmic ABC transporter protein YP_001328088.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01978 putative sugar transport system permease ABC transporter protein YP_001328089.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01979 putative sugar transport system permease ABC transporter protein YP_001328090.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01980 putative sugar transport system ATP-binding ABC transporter protein YP_001328091.1 PFAM: cytochrome c class I; KEGG: sme:SMc01981 putative cytochrome c transmembrane protein YP_001328092.1 PFAM: cytochrome c oxidase subunit II; KEGG: sme:SMc01982 cytochrome c oxidase subunit II YP_001328093.1 TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I; KEGG: sme:SMc01983 cytochrome c oxidase subunit I YP_001328094.1 PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc01984 cytochrome c oxidase subunit III YP_001328095.1 PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc01985 cytochrome c oxidase subunit III YP_001328096.1 KEGG: sme:SMc01986 hypothetical protein YP_001328097.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); KEGG: sme:SMc01987 putative dehydrogenase protein YP_001328098.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMb20716 hypothetical protein YP_001328099.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMb20715 putative transcriptional regulator, LysR family protein YP_001328100.1 PFAM: regulatory protein TetR; KEGG: rsp:RSP_1486 regulatory protein, TetR family YP_001328101.1 KEGG: jan:Jann_2415 hypothetical protein YP_001328102.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; KEGG: sme:SMc02024 hypothetical protein YP_001328103.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc02025 putative dipeptide-binding periplasmic protein YP_001328104.1 KEGG: sme:SMc02026 putative beta-lactamase precursor protein YP_001328105.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc02027 putative dipeptide transport ATP-binding ABC transporter protein YP_001328106.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02028 putative dipeptide transport system permease ABC transporter protein YP_001328107.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02029 putative dipeptide transport system permease ABC transporter protein YP_001328108.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc02030 putative transcription regulator protein YP_001328109.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02031 putative permease protein YP_001328110.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02032 putative ATP-binding ABC transporter protein YP_001328111.1 KEGG: sme:SMc02033 putative periplasmic binding protein YP_001328112.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02034 putative oxidoreductase protein YP_001328113.1 PFAM: aldehyde dehydrogenase; KEGG: mpt:Mpe_A0361 lactaldehyde dehydrogenase YP_001328114.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ter:Tery_0562 alcohol dehydrogenase, zinc-binding YP_001328115.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mes:Meso_3153 short-chain dehydrogenase/reductase SDR YP_001328116.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: mes:Meso_3152 cupin 2, conserved barrel YP_001328117.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: vei:Veis_0884 glucose-methanol-choline oxidoreductase YP_001328118.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mlo:mll7151 sugar ABC transporter, ATP-binding protein YP_001328119.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: pfu:PF1933 putative sugar transport ATP-hydrolyzing YP_001328121.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_2612 binding-protein-dependent transport systems inner membrane component YP_001328122.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dge:Dgeo_2820 binding-protein-dependent transport systems inner membrane component YP_001328123.1 PFAM: extracellular solute-binding protein family 1; KEGG: she:Shewmr4_1212 extracellular solute-binding protein, family 1 YP_001328124.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: sme:SMc02035 putative malate dehydrogenase YP_001328125.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc02036 putative transcription regulator protein YP_001328126.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02037 putative oxidoreductase protein YP_001328127.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001328128.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02039 putative oxidoreductase protein YP_001328129.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02041 putative oxidoreductase protein YP_001328130.1 catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate YP_001328131.1 TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: sme:SMc02043 probable KHG/KDPG aldolase (includes: 4-hydroxy-2-oxoglutarate aldolase, 2-dehydro-3-deoxyphosphogluconate aldolase) protein YP_001328132.1 KEGG: sme:SMc02044 hypothetical protein YP_001328133.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc02045 putative oxidoreductase protein YP_001328134.1 KEGG: sme:SMc02332 hypothetical protein YP_001328135.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMc02460 hypothetical protein YP_001328136.1 TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sme:SMc02333 putative deoxyribose-phosphate aldolase YP_001328137.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc02334 putative pentose kinase transmembrane protein YP_001328138.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc02335 putative pentose kinase protein YP_001328139.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc02336 putative oxidoreductase protein YP_001328140.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02452 putative transport system permease ABC transporter protein YP_001328141.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02337 putative ATP-binding ABC transporter protein YP_001328142.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMc02338 putative periplasmic binding ABC transporter protein YP_001328143.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02339 putative oxidoreductase protein YP_001328144.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMc02340 putative transcription regulator protein YP_001328145.1 PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc02341 putative sugar kinase protein YP_001328146.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001328147.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sme:SMa0252 hypothetical protein YP_001328148.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sme:SMa0250 conserved hypothetical DedA-like protein YP_001328149.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: sme:SMa0249 hypothetical protein YP_001328150.1 KEGG: sme:SMa0247 hypothetical protein YP_001328151.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMa0246 putative GntR-family transcriptional regulator YP_001328152.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMa0244 hypothetical protein YP_001328153.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMa0241 hypothetical protein YP_001328154.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMa0237 putative D-threonine YP_001328155.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001328156.1 KEGG: rso:RS05859 probable peptide synthetase protein YP_001328157.1 PFAM: periplasmic binding protein; KEGG: atu:Atu3688 ABC transporter, membrane spanning protein [iron(III) dicitrate] YP_001328158.1 PFAM: transport system permease protein; KEGG: atc:AGR_L_2296 iron(III) dicitrate transport system permease protein FecC YP_001328159.1 PFAM: transport system permease protein; KEGG: atc:AGR_L_2295 iron(III) dicitrate transport system permease protein FecD YP_001328160.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_L_2292 iron (III) dicitrate transport system (permease) YP_001328161.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: atc:AGR_L_2303 hypothetical protein YP_001328162.1 PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: pde:Pden_4240 FAD-binding 9, siderophore-interacting domain protein YP_001328163.1 PFAM: peptidase M23B; KEGG: sme:SMc02432 hypothetical protein YP_001328164.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: sme:SMc02433 probable ATP-dependent protease (heat shock protein) YP_001328165.1 KEGG: sme:SMc02434 hypothetical protein YP_001328166.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; ribosomal L11 methyltransferase; KEGG: sme:SMc02435 putative methyltransferase protein YP_001328167.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001328168.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: sme:SMc02437 phosphotransferase system, enzyme I YP_001328169.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001328170.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ret:RHE_CH01179 probable ABC transporter, ATP-binding protein YP_001328171.1 Involved in ubiquinone biosynthesis YP_001328172.1 PFAM: protein of unknown function DUF1178; KEGG: sme:SMc02441 hypothetical protein YP_001328173.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sme:SMc02442 putative hydrolase protein YP_001328174.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: sme:SMc02443 probable glutaredoxin 3 protein YP_001328175.1 PFAM: phosphoribosyltransferase; KEGG: sme:SMc02444 hypothetical protein YP_001328176.1 KEGG: sme:SMc02445 hypothetical protein YP_001328177.1 PFAM: Flp/Fap pilin component; KEGG: sme:SMc02446 putative pilus assembly protein PilA YP_001328178.1 KEGG: sme:SMc02447 hypothetical protein YP_001328179.1 PFAM: NUDIX hydrolase; KEGG: sme:SMc02448 putative mutator protein 7,8-dihydro-8-oxoguanine-triphosphatase YP_001328180.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02449 putative acetyltransferase protein YP_001328181.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001328182.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: sme:SMc02451 putative outer membrane protein YP_001328183.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001328184.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00744 putative transport protein transmembrane YP_001328185.1 PFAM: multi antimicrobial extrusion protein MatE; polysaccharide biosynthesis protein; KEGG: sme:SMc00743 hypothetical protein YP_001328186.1 KEGG: sme:SMc00742 hypothetical protein YP_001328187.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00741 putative fatty-acid-CoA ligase protein YP_001328188.1 KEGG: sme:SMc00738 hypothetical protein YP_001328189.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sme:SMc00737 hypothetical protein YP_001328190.1 PFAM: HhH-GPD family protein; KEGG: sme:SMc00736 putative DNA-3-methyladenine glycosidase II protein YP_001328191.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001328192.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN; KEGG: sme:SMc00734 putative ribonuclease RNase BN (RBN) transmembrane protein YP_001328193.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00733 short chain dehydrogenase YP_001328194.1 KEGG: sme:SMc00732 hypothetical protein YP_001328195.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: sme:SMc00731 hypothetical protein YP_001328196.1 PFAM: Rhomboid family protein; KEGG: sme:SMc00730 hypothetical protein YP_001328197.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: sme:SMc00729 putative electron transfer flavoprotein beta-subunit beta-ETF flavoprotein small subunit YP_001328198.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: sme:SMc00728 putative electron transfer flavoprotein alpha-subunit alpha-ETF flavoprotein YP_001328199.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001328200.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMc00726 putative thiol:disulfide interchange redox-active center transmembrane protein YP_001328201.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001328202.1 KEGG: sme:SMc00724 hypothetical/unknown protein YP_001328203.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: sme:SMc00723 probable diaminopimelate DAP decarboxylase protein YP_001328204.1 KEGG: sme:SMc00722 hypothetical protein YP_001328205.1 PFAM: response regulator receiver; KEGG: sme:SMc00720 putative 2-component receiver domain protein YP_001328206.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: sme:SMc00719 hypoxanthine-guanine phosphoribosyltransferase YP_001328207.1 KEGG: sme:SMc00718 hypothetical protein YP_001328208.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00717 putative ATP-binding ABC transporter protein YP_001328209.1 KEGG: sme:SMc00716 hypothetical transmembrane protein YP_001328210.1 PFAM: protein of unknown function DUF218; KEGG: sme:SMc00715 hypothetical protein YP_001328211.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc00714 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (PlsC) protein YP_001328212.1 PFAM: ChaC family protein; KEGG: sme:SMc00713 putative cation transport protein YP_001328213.1 KEGG: sme:SMc00712 hypothetical protein YP_001328214.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate YP_001328215.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001328216.1 PFAM: Methyltransferase type 11; KEGG: sme:SMc00709 hypothetical protein YP_001328217.1 PFAM: beta-lactamase domain protein; KEGG: sme:SMc00708 putative hydroxyacylglutathione hydrolase (glyoxalase II) (GLX II) protein YP_001328218.1 PFAM: protein of unknown function DUF985; KEGG: sme:SMc00707 hypothetical protein YP_001328219.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00706 hypothetical protein YP_001328220.1 KEGG: sme:SMc00705 conserved hypothetical signal peptide protein YP_001328221.1 required for 70S ribosome assembly YP_001328222.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: sme:SMc00703 hypothetical protein YP_001328223.1 KEGG: sme:SMc00702 hypothetical signal peptide protein YP_001328224.1 KEGG: sme:SMc00701 probable cobalamin biosynthesis protein; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase CobT subunit; SMART: von Willebrand factor type A YP_001328225.1 TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities AAA_5; KEGG: sme:SMc00700 probable cobalamin biosynthesis protein YP_001328226.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sme:SMc00699 hypothetical protein YP_001328227.1 PFAM: BolA family protein; KEGG: sme:SMc00698 putative transcription regulator protein YP_001328228.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sme:SMc00697 hypothetical protein YP_001328229.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001328230.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001328231.1 KEGG: sme:SMc00692 hypothetical signal peptide protein YP_001328232.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001328233.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001328234.1 PFAM: protein of unknown function DUF949; KEGG: sme:SMc00689 hypothetical lipoprotein YP_001328235.1 PFAM: SirA family protein; KEGG: sme:SMc00688 hypothetical protein YP_001328236.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sme:SMc00684 hypothetical protein YP_001328237.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: sme:SMc00683 putative penicillin-binding protein YP_001328238.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sme:SMc00682 putative hippurate hydrolase protein YP_001328239.1 PFAM: regulatory protein AsnC/Lrp family; regulatory protein ArsR; KEGG: sme:SMc00681 probable leucine-responsive regulatorY protein YP_001328240.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00680 putative zinc-type alcohol dehydrogenase protein YP_001328241.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: sme:SMc00679 putative transcription regulator protein YP_001328242.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc00678 putative transcription regulator protein YP_001328243.1 PFAM: aminoglycoside phosphotransferase; peptidase M23B; aminotransferase class-III; KEGG: sme:SMc00677 hypothetical protein YP_001328244.1 SMART: extracellular solute-binding protein family 3; KEGG: sme:SMc00676 putative amino acid-binding periplasmic signal peptide protein YP_001328245.1 PFAM: aminoglycoside phosphotransferase; aminotransferase class-III; KEGG: sme:SMc00675 hypothetical protein YP_001328246.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMc00674 putative histidine utilization repressor transcription regulator protein YP_001328247.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001328248.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc00672 histidine-binding periplasmic signal peptide protein YP_001328249.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc00671 histidine transport system permease ABC transporter protein YP_001328250.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc00670 histidine transport ATP-binding ABC transporter protein YP_001328251.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: sme:SMc00669 putative histidine ammonia-lyase protein YP_001328252.1 PFAM: nucleoside recognition domain protein; KEGG: sme:SMc00668 hypothetical, transmembrane protein YP_001328253.1 PFAM: protein of unknown function DUF886; KEGG: sme:SMc00667 hypothetical protein YP_001328254.1 KEGG: sme:SMc00666 hypothetical protein YP_001328255.1 KEGG: sme:SMc00665 hypothetical/unknown protein YP_001328256.1 KEGG: sme:SMc00664 hypothetical signal peptide protein YP_001328257.1 KEGG: sme:SMc00663 hypothetical protein YP_001328258.1 KEGG: sme:SMc00662 hypothetical/unknown protein YP_001328259.1 KEGG: sme:SMc00660 hypothetical signal peptide protein YP_001328260.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMc01714 hypothetical protein YP_001328261.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sme:SMc01715 hypothetical protein YP_001328262.1 KEGG: pfo:Pfl_2954 beta-lactamase-like YP_001328263.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMa1724 hypothetical protein YP_001328264.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMa1725 putative AraC-family transcriptional regulator YP_001328265.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001328266.1 PFAM: regulatory protein LuxR; KEGG: sme:SMc00658 putative transcription regulator protein YP_001328267.1 PFAM: protein of unknown function DUF1153; KEGG: sme:SMc00657 hypothetical protein YP_001328268.1 KEGG: sme:SMc00656 hypothetical protein YP_001328269.1 KEGG: sme:SMc00655 hypothetical protein YP_001328270.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc00654 response regulator,controls chromosomal replication initiation protein YP_001328272.1 PFAM: response regulator receiver; KEGG: sme:SMc00653 putative 2-component receiver domain protein YP_001328273.1 KEGG: sme:SMc00652 hypothetical protein YP_001328274.1 PFAM: uncharacterised conserved protein UCP033924; KEGG: sme:SMc00651 hypothetical protein YP_001328275.1 KEGG: sme:SMc00650 hypothetical protein YP_001328276.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sme:SMc00649 putative tRNA/rRNA methyltransferase protein YP_001328277.1 KEGG: sme:SMc00648 hypothetical protein YP_001328278.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sme:SMc00647 putative ribosomal large subunit pseudouridine synthase protein YP_001328279.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001328280.1 KEGG: sme:SMc00644 hypothetical protein YP_001328281.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001328282.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00642 hypothetical protein YP_001328283.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001328284.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001328285.1 KEGG: sme:SMc00639 putative heat resistant agglutinin 1 signal peptide protein YP_001328286.1 PFAM: porin opacity type; KEGG: sme:SMc00638 putative heat resistant agglutinin 1 protein YP_001328287.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001328288.1 KEGG: sme:SMc04459 probable metalloprotease transmembrane protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001328289.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: sme:SMc02940 hypothetical protein YP_001328290.1 TIGRFAM: Tol-Pal system YbgF; KEGG: sme:SMc02941 hypothetical protein YP_001328291.1 TIGRFAM: Peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: sme:SMc02942 probable peptidoglycan-associated lipoprotein precursor YP_001328292.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001328293.1 KEGG: sme:SMc03956 hypothetical signal peptide protein YP_001328294.1 TIGRFAM: Biopolymer transport TolR; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sme:SMc03957 putative transport transmembrane protein YP_001328295.1 TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: sme:SMc03958 putative transport transmembrane protein YP_001328296.1 TIGRFAM: DNA ligase D; DNA ligase D 3'-phosphoesterase domain; DNA polymerase LigD polymerase domain; DNA polymerase LigD ligase region; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sme:SMc03959 hypothetical protein YP_001328297.1 TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: sme:SMc03960 hypothetical protein YP_001328298.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: sme:SMc03961 sulfolipid (UDP-sulfoquinovose) biosynthesis protein YP_001328299.1 PFAM: glycosyl transferase family 8; KEGG: sme:SMc04081 glycosyl transferase (sulfolipid biosynthesis) protein YP_001328300.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMc03963 sulfolipid biosynthesis protein YP_001328301.1 PFAM: metallophosphoesterase; KEGG: sme:SMc03964 hypothetical transmembrane protein YP_001328302.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001328303.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001328304.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001328305.1 PFAM: luciferase family protein; KEGG: sme:SMc03968 putative oxidoreductase protein YP_001328306.1 PFAM: protein of unknown function DUF28; KEGG: sme:SMc03969 hypothetical protein YP_001328307.1 KEGG: sme:SMc03970 hypothetical protein YP_001328308.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sme:SMc03971 probable multidrug-efflux system transmembrane protein YP_001328309.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc03972 putative multidrug efflux system transmembrane protein YP_001328310.1 PFAM: metallophosphoesterase; KEGG: sme:SMc03973 hypothetical protein YP_001328311.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: sme:SMc03974 hypothetical protein YP_001328312.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc03975 putative transcription regulator protein YP_001328313.1 PFAM: protein of unknown function DUF710; KEGG: sme:SMc03976 hypothetical protein YP_001328314.1 KEGG: sme:SMc03977 hypothetical protein YP_001328315.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001328316.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: sme:SMc03979 glyceraldehyde-3-phosphate dehydrogenase YP_001328317.1 PFAM: protein of unknown function DUF1089; KEGG: sme:SMc03980 hypothetical protein YP_001328318.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001328319.1 PFAM: fructose-bisphosphate aldolase class-I; KEGG: sme:SMc03983 probable fructose-bisphosphate aldolase class I protein YP_001328320.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sme:SMc03984 hypothetical protein YP_001328321.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc03985 probable adenylate/guanylate cyclase protein YP_001328322.1 KEGG: sme:SMc03986 hypothetical protein YP_001328323.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc03987 putative transport transmembrane protein YP_001328324.1 PFAM: protein of unknown function DUF1192; KEGG: sme:SMc03988 hypothetical protein YP_001328325.1 PFAM: protein of unknown function DUF1465; KEGG: sme:SMc03989 hypothetical protein YP_001328326.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001328327.1 TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03991 probable ABC transporter ATP-binding transmembrane protein YP_001328328.1 PFAM: OmpA/MotB domain protein; KEGG: sme:SMc03992 hypothetical transmembrane protein YP_001328329.1 KEGG: sme:SMc03993 hypothetical protein YP_001328330.1 PFAM: inositol monophosphatase; KEGG: sme:SMc03994 putative myo-inositol-1(or 4)-monophosphatase YP_001328331.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sme:SMc03995 hypothetical protein YP_001328332.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole YP_001328333.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMc03997 hypothetical transmembrane protein YP_001328334.1 PFAM: regulatory protein ArsR; KEGG: sme:SMc03998 hypothetical transcription regulator protein YP_001328335.1 PFAM: protein of unknown function DUF465; KEGG: sme:SMc03999 hypothetical protein YP_001328336.1 PFAM: protein of unknown function DUF465; KEGG: sme:SMc04000 hypothetical protein YP_001328337.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: sme:SMc04001 probable phosphoribosylaminoimidazole carboxylase catalytic subunit protein YP_001328338.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001328339.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001328340.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc04004 hypothetical signal peptide protein YP_001328341.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001328342.1 PFAM: protein of unknown function DUF1036; KEGG: sme:SMc04006 hypothetical protein YP_001328343.1 PFAM: N-formylglutamate amidohydrolase; KEGG: sme:SMc04007 hypothetical protein YP_001328344.1 PFAM: protein of unknown function DUF1244; KEGG: sme:SMc04008 hypothetical protein YP_001328345.1 KEGG: sme:SMc04009 hypothetical protein YP_001328347.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: sme:SMc04010 hypothetical protein YP_001328348.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sme:SMc04011 putative sigma-54-dependent transcription regulator protein YP_001328349.1 TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F; KEGG: sme:SMc04012 putative oligoendopeptidase F protein YP_001328350.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_001328351.1 KEGG: sme:SMc04014 4-amino-4-deoxychorismate lyase YP_001328352.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMc04015 hypothetical protein YP_001328353.1 PFAM: homospermidine synthase; KEGG: sme:SMc04016 probable homospermidine synthase protein YP_001328354.1 KEGG: sme:SMc04017 probable outer membrane lipoprotein YP_001328355.1 PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sme:SMc04018 probable 5'-nucleotidase precursor (signal peptide) protein YP_001328356.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001328357.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: ret:RHE_PA00028 putative glycerol-3-phosphate dehydrogenase (NAD(P)+) protein YP_001328358.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: ret:RHE_PA00027 probable oxidoreductase protein, short-chain dehydrogenase reductase family YP_001328359.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ret:RHE_PA00026 probable sugar ABC transporter, ATP-binding protein YP_001328360.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ret:RHE_PA00025 probable oxidoreductase protein, short-chain dehydrogenase-reductase family YP_001328361.1 PFAM: extracellular solute-binding protein family 1; KEGG: rde:RD1_3621 ABC transporter, substrate-binding protein, putative YP_001328362.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_3620 sugar ABC transporter permease protein, putative YP_001328363.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_3619 ABC transporter, permease protein, putative YP_001328364.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001328365.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; KEGG: ret:RHE_PA00023 putative hydrolase protein YP_001328366.1 PFAM: 3-dehydroquinate synthase; KEGG: ret:RHE_PA00022 putative glycerol 1-phosphate dehydrogenase protein (L-arabinose utilization protein) protein YP_001328367.1 PFAM: putative sugar-binding domain protein; KEGG: ret:RHE_PA00021 putative transcriptional regulator protein, AsnC/GntR family YP_001328368.1 PFAM: carbohydrate kinase FGGY; KEGG: ret:RHE_PA00020 xylulokinase protein YP_001328369.1 PFAM: band 7 protein; KEGG: sme:SMc04020 hypothetical protein YP_001328370.1 PFAM: protein of unknown function DUF107; KEGG: sme:SMc04021 hypothetical protein YP_001328371.1 KEGG: sme:SMc04022 hypothetical protein YP_001328372.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sme:SMc04023 probable UTP--glucose-1-phosphate uridylyltransferase protein YP_001328373.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMc04024 putative membrane-bound lytic murein transglycosylase protein YP_001328374.1 PFAM: protein of unknown function DUF459; KEGG: sme:SMc04025 hypothetical protein YP_001328375.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001328376.1 PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein YP_001328377.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc04029 putative low specificity L-threonine aldolase protein YP_001328378.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rle:RL4087 putative LysR family transcriptional regulator YP_001328379.1 PFAM: Bile acid:sodium symporter; KEGG: sme:SMc04030 hypothetical protein YP_001328380.1 PFAM: heat shock protein Hsp20; KEGG: sme:SMc04040 probable heat shock protein YP_001328381.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc04041 probable lysophospholipase L2 protein YP_001328382.1 TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: sme:SMc04042 putative monophosphatase protein YP_001328383.1 PFAM: N-formylglutamate amidohydrolase; KEGG: sme:SMc04043 hypothetical protein YP_001328384.1 PFAM: response regulator receiver; KEGG: sme:SMc04044 putative 2-component receiver domain protein YP_001328385.1 PFAM: HicB family protein; KEGG: sme:SMa1990 hypothetical protein YP_001328386.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: pcu:pc0710 hypothetical protein YP_001328388.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001328389.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc04046 hypothetical protein YP_001328390.1 PFAM: regulatory protein MarR; KEGG: rle:RL0596 putative MarR family transcriptional regulator YP_001328391.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: sme:SMc04047 probable pseudoazurin (blue copper protein) YP_001328392.1 KEGG: sme:SMc04048 putative cytochrome c protein YP_001328393.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: sme:SMc04049 putative sulfite oxidase protein YP_001328394.1 KEGG: sme:SMc04050 hypothetical protein YP_001328395.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein YP_001328396.1 PFAM: regulatory protein MarR; KEGG: sme:SMc04052 putative transcription regulator protein YP_001328397.1 PFAM: protein of unknown function DUF1579; KEGG: sme:SMc04053 hypothetical protein YP_001328398.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc04054 hypothetical protein YP_001328399.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc04055 putative transcription regulator protein YP_001328400.1 PFAM: aldo/keto reductase; KEGG: sme:SMc04056 putative oxidoreductase protein YP_001328401.1 PFAM: protein of unknown function DUF403; protein of unknown function DUF404; protein of unknown function DUF407; KEGG: sme:SMc04057 hypothetical protein YP_001328402.1 PFAM: transglutaminase domain protein; transglutaminase domain protein; KEGG: sme:SMc04058 hypothetical protein YP_001328403.1 SMART: von Willebrand factor type A; KEGG: sme:SMc04059 hypothetical protein YP_001328404.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: sme:SMc04460 probable glycogen phosphorylase protein YP_001328405.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001328406.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001328407.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001328408.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001328409.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sme:SMc03926 probable glycosyl hydrolase protein YP_001328410.1 PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc03927 putative nodulation protein YP_001328411.1 KEGG: sme:SMc03928 hypothetical protein YP_001328412.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc03929 putative zinc-type alcohol dehydrogenase transmembrane protein YP_001328413.1 KEGG: sfu:Sfum_2194 hypothetical protein YP_001328414.1 TIGRFAM: sarcosine oxidase, gamma subunit family; PFAM: Sarcosine oxidase gamma subunit; KEGG: sme:SMc03930 putative sarcosine oxidase gamma subunit protein YP_001328415.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; KEGG: sme:SMc03931 putative sarcosine oxidase alpha subunit transmembrane protein YP_001328416.1 TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: sme:SMc03932 putative sarcosine oxidase delta subunit protein YP_001328417.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc03933 putative sarcosine oxidase subunit B protein YP_001328418.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001328419.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sme:SMc03935 hypothetical protein YP_001328420.1 PFAM: protein of unknown function DUF992; KEGG: sme:SMc03936 conserved hypothetical signal peptide protein YP_001328421.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc03937 putative adenylate/guanylate cyclase protein YP_001328422.1 PFAM: NAD(P) transhydrogenase beta subunit; KEGG: sme:SMc03938 probable NAD(P) transhydrogenase subunit beta transmembrane protein YP_001328423.1 KEGG: sme:SMc03939 probable NAD(P) transhydrogenase subunit alpha PART 2 transmembrane protein YP_001328424.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sme:SMc03950 probable proton-translocating nicotinamide nucleotide transhydrogenase subunit protein YP_001328425.1 PFAM: aa3 type cytochrome c oxidase subunit IV; KEGG: sme:SMc03941 hypothetical protein YP_001328426.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein; KEGG: sme:SMc03942 hypothetical protein YP_001328427.1 PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: sme:SMc03943 hypothetical protein YP_001328428.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc04462 glycerate dehydrogenase YP_001328429.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sme:SMc02975 putative phosphoenolpyruvate carboxykinase regulator transcription regulator protein YP_001328430.1 PFAM: regulatory protein MarR; KEGG: sme:SMc02976 putative transcription regulator protein YP_001328431.1 PFAM: Creatininase; KEGG: sme:SMc02977 putative creatinine amidohydrolase YP_001328432.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sme:SMc02978 hypothetical protein YP_001328433.1 SMART: WD-40 repeat protein; KEGG: sme:SMc02979 hypothetical protein YP_001328434.1 KEGG: sme:SMc02980 hypothetical protein YP_001328435.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc02981 putative amino acid efflux transmembrane protein YP_001328436.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02982 hypothetical protein YP_001328437.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: sme:SMc02983 putative ornithine, dap, or arginine decarboxylase protein YP_001328438.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc02984 putative transcription regulator protein YP_001328439.1 PFAM: protein of unknown function DUF1007; KEGG: sme:SMc02985 hypothetical protein YP_001328440.1 PFAM: high-affinity nickel-transporter; KEGG: sme:SMc02986 hypothetical protein YP_001328441.1 KEGG: sme:SMc02989 hypothetical protein YP_001328442.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc03151 hypothetical protein YP_001328443.1 PFAM: protein of unknown function DUF533; KEGG: sme:SMc03152 hypothetical protein YP_001328444.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001328445.1 PFAM: adenylate cyclase; KEGG: sme:SMc03154 hypothetical protein YP_001328446.1 PFAM: CHAD domain containing protein; KEGG: sme:SMc03155 hypothetical protein YP_001328447.1 PFAM: Rhodanese domain protein; KEGG: sme:SMc03156 conserved hypothetical protein YP_001328448.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sme:SMc03157 putative outer membrane lipoprotein transmembrane YP_001328449.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03158 putative permease ABC transporter protein YP_001328450.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03159 putative ATP-binding ABC transporter protein YP_001328451.1 PFAM: glycoside hydrolase family 1; KEGG: sme:SMc03160 probable beta-glucosidase protein YP_001328452.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc03161 putative oxidoreductase protein YP_001328453.1 PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc03162 hypothetical protein YP_001328454.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001328455.1 KEGG: mlo:mll5035 hypothetical protein YP_001328456.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: sme:SMc03164 putative xylulose kinase protein YP_001328457.1 PFAM: regulatory protein LacI; KEGG: sme:SMc03165 putative transcription regulator protein YP_001328458.1 PFAM: peptidase S41; KEGG: ctc:CTC01801 hypothetical protein YP_001328459.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc03167 putative multidrug efflux system protein YP_001328460.1 PFAM: secretion protein HlyD family protein; KEGG: sme:SMc03168 putative multidrug efflux system protein YP_001328461.1 PFAM: regulatory protein TetR; KEGG: sme:SMc03169 putative transcription regulator protein YP_001328462.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: sme:SMc03170 putative transcription regulator protein YP_001328463.1 PFAM: Integral membrane protein TerC; KEGG: sme:SMc03171 hypothetical protein YP_001328464.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001328465.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001328466.1 KEGG: sme:SMc03174 hypothetical unknown transmembrane protein YP_001328467.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: sme:SMc03175 putative nucleoside hydrolase protein YP_001328468.1 KEGG: sme:SMc03176 putative mRNA 3-end processing factor YP_001328469.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001328470.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE domain protein; PAS fold-3 domain protein; KEGG: sme:SMc03178 hypothetical protein YP_001328471.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001328472.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001328473.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001328474.1 PFAM: cation antiporter; KEGG: sme:SMc03182 multicomponent K+:H+ antiporter subunit E YP_001328475.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001328476.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+ antiporter subunit; KEGG: sme:SMc03184 PH adaptation potassium efflux system G transmembrane protein YP_001328477.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03187 probable precorrin-4 C11-methyltransferase protein YP_001328478.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc03188 probable precorrin-6Y C5,15-methyltransferase (decarboxylating) protein YP_001328479.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001328480.1 catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine YP_001328481.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001328482.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001328483.1 TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: sme:SMc03193 probable cobalamin biosynthesis protein YP_001328484.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_001328485.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001328486.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc03196 putative molybdate-binding periplasmic ABC transporter protein YP_001328487.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001328488.1 TIGRFAM: molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase; KEGG: sme:SMc03198 putative molybdenum transport ATP-binding ABC transporter protein YP_001328489.1 PFAM: regulatory protein LysR; KEGG: sme:SMc03199 putative molybdenum transport associated protein YP_001328490.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc03200 putative amino acid deaminase transmembrane protein YP_001328491.1 PFAM: dehydrogenase E1 component; KEGG: sme:SMc03201 probable 2-oxoisovalerate dehydrogenase alpha subunit protein YP_001328492.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: sme:SMc03202 probable 2-oxoisovalerate dehydrogenase beta subunit protein YP_001328493.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sme:SMc03203 probable lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex protein YP_001328494.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001328495.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001328496.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: sme:SMc03206 maleylacetoacetate isomerase (glutathione transferase ZETA 1) protein YP_001328497.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sme:SMc03207 putative aromatic amino acid degradation protein YP_001328498.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_001328499.1 PFAM: regulatory protein MarR; KEGG: sme:SMc03209 putative transcription regulator protein YP_001328500.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc03210 putative transcription regulator protein YP_001328501.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc03211 putative 4-hydroxyphenylpyruvate dioxygenase protein YP_001328502.1 PFAM: regulatory protein LuxR; KEGG: sme:SMc03150 putative transcription regulator protein YP_001328503.1 KEGG: sme:SMc03149 hypothetical protein YP_001328504.1 KEGG: sme:SMc03145 hypothetical unknown protein YP_001328505.1 PFAM: Tetratricopeptide TPR_4; KEGG: sme:SMc03144 hypothetical protein YP_001328506.1 KEGG: sme:SMc03143 hypothetical protein YP_001328507.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mlo:mll2297 hypothetical protein YP_001328508.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMc03140 putative transcription regulator protein YP_001328509.1 PFAM: sugar isomerase (SIS); KEGG: sme:SMc03139 hypothetical protein YP_001328510.1 PFAM: PfkB domain protein; KEGG: sme:SMc03138 putative sugar kinase protein YP_001328511.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03135 putative amino-acid transport system ATP-binding ABC transporter protein YP_001328512.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc03134 hypothetical protein YP_001328513.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03133 putative amino-acid transport system permease ABC transporter protein YP_001328514.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc03132 putative oxidoreductase protein YP_001328515.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMc03131 putative amino acid-binding periplasmic ABC transporter protein YP_001328516.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc03130 hypothetical protein YP_001328517.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: sme:SMc03129 putative glycerophosphoryl diester phosphodiesterase YP_001328518.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03128 putative transport system permease ABC transporter protein YP_001328519.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03127 putative transport system permease ABC transporter protein YP_001328520.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc03126 putative transport system ATP-binding ABC transporter protein YP_001328521.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc03125 putative transport system ATP-binding ABC transporter protein YP_001328522.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc03124 putative periplasmic binding ABC transporter protein YP_001328523.1 PFAM: putative sugar-binding domain protein; KEGG: sme:SMc03123 putative transcriptional regulator protein YP_001328524.1 KEGG: rpe:RPE_4065 PilT protein domain protein YP_001328525.1 PFAM: Integrase catalytic region; KEGG: atc:AGR_L_547 hypothetical protein YP_001328526.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_L_545 hypothetical protein YP_001328527.1 KEGG: fra:Francci3_0246 Rv0623-like transcription factor YP_001328528.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc03122 putative transcription regulator protein YP_001328529.1 KEGG: sme:SMc03121 putative periplasmic binding ABC transporter protein YP_001328530.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03120 putative ATP-binding ABC transporter protein YP_001328531.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03119 putative ATP-binding ABC transporter protein YP_001328532.1 PFAM: inner-membrane translocator; KEGG: sme:SMc03118 putative permease ABC transporter protein YP_001328533.1 PFAM: inner-membrane translocator; KEGG: sme:SMc03117 putative permease ABC transporter protein YP_001328534.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: sme:SMc03116 putative alcohol dehydrogenase protein YP_001328535.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001328536.1 PFAM: N-acylglucosamine 2-epimerase; KEGG: sme:SMc03111 mannose-6-phosphate isomerase protein YP_001328537.1 PFAM: protein of unknown function DUF336; KEGG: sme:SMc03110 conserved hypothetical protein YP_001328538.1 PFAM: ROK family protein; KEGG: sme:SMc03109 hypothetical protein YP_001328539.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: rle:pRL100052 putative cold shock protein CspA YP_001328541.1 PFAM: PRC-barrel domain protein; KEGG: sme:SMb20522 hypothetical protein YP_001328542.1 KEGG: rle:RL0462 putative transmembrane protein YP_001328543.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sme:SMc03106 hypothetical protein YP_001328544.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001328545.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001328546.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: sme:SMc03103 putative carbon monoxide dehydrogenase medium subunit transmembrane protein YP_001328547.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: sme:SMc03102 putative carbon monoxide dehydrogenase large subunit transmembrane protein YP_001328548.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sme:SMc03101 putative carbon monoxide dehydrogenase small subunit protein YP_001328549.1 PFAM: 17 kDa surface antigen; KEGG: sme:SMc03100 hypothetical protein YP_001328550.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc03099 putative adenylate cyclase protein YP_001328551.1 PFAM: alpha/beta hydrolase fold; KEGG: sme:SMc03098 hypothetical protein YP_001328552.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sme:SMc03097 putative outer membrane protein YP_001328553.1 PFAM: protein of unknown function DUF490; KEGG: sme:SMc03096 hypothetical signal peptide protein YP_001328554.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc03093 hypothetical protein YP_001328555.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc03092 putative transcription regulator protein YP_001328556.1 TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sme:SMc03091 probable arginase protein YP_001328557.1 PFAM: CheW domain protein; KEGG: sme:SMc03090 putative chemotaxis protein YP_001328558.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: sme:SMc03087 probable chemoreceptor (methyl-accepting chemotaxis protein) YP_001328559.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: hne:HNE_2108 ISHne4, transposase YP_001328560.1 KEGG: sme:SMc03086 putative NAD-dependent formate dehydrogenase delta subunit protein YP_001328561.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001328562.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMc04444 probable NAD-dependent formate dehydrogenase alpha subunit protein YP_001328563.1 PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: sme:SMc02525 putative NAD-dependent formate dehydrogenase beta subunit protein YP_001328564.1 catalyzes the oxidation of formate to carbon dioxide and hydrogen using NAD or NADP as the acceptor YP_001328565.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc02523 putative transcription regulator protein YP_001328566.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02522 putative oxidoreductase protein YP_001328567.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: sme:SMc02521 putative glycerol-3-phosphate regulon repressor transcription regulator protein YP_001328568.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001328569.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02519 putative ATP-binding ABC transporter protein YP_001328570.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02518 putative ATP-binding ABC transporter protein YP_001328571.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02517 putative transport system permease ABC transporter protein YP_001328572.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02516 putative transport system permease ABC transporter protein YP_001328573.1 KEGG: sme:SMc02515 hypothetical protein YP_001328574.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc02514 putative multiple sugar transport system substrate-binding protein YP_001328575.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMc02512 putative permease transmembrane protein YP_001328576.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc02511 hypothetical protein YP_001328577.1 PFAM: ferric-uptake regulator; KEGG: sme:SMc02510 probable ferric uptake regulation protein YP_001328578.1 PFAM: periplasmic solute binding protein; KEGG: sme:SMc02509 putative iron-binding periplasmic ABC transporter protein YP_001328579.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02508 putative iron transport ATP-binding ABC transporter protein YP_001328580.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: sme:SMc02507 putative iron transport system membrane ABC transporter protein YP_001328581.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: sme:SMc02506 putative iron transport system membrane ABC transporter protein YP_001328582.1 KEGG: sme:SMc02505 hypothetical protein YP_001328583.1 PFAM: regulatory protein AsnC/Lrp family; Helix-turn-helix type 11 domain protein; KEGG: sme:SMc02504 putative transcription regulator protein YP_001328584.1 PFAM: Saccharopine dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sme:SMc02503 hypothetical protein YP_001328585.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001328586.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001328587.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001328588.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001328589.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001328590.1 KEGG: sme:SMc02497 hypothetical protein YP_001328591.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001328592.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001328593.1 KEGG: sme:SMc02494 hypothetical protein YP_001328594.1 KEGG: sme:SMc02492 hypothetical protein YP_001328595.1 KEGG: sme:SMc02491 hypothetical protein YP_001328596.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc02490 hypothetical protein YP_001328597.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001328598.1 PFAM: GumN family protein; KEGG: sme:SMc02488 hypothetical protein YP_001328599.1 KEGG: atc:AGR_C_4769 hypothetical protein YP_001328600.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001328601.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02486 putative oxidoreductase protein YP_001328602.1 KEGG: sme:SMc02485 conserved hypothetical signal peptide protein YP_001328603.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc02484 putative amino acid efflux transmembrane protein YP_001328604.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001328605.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001328606.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001328607.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001328608.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001328609.1 PFAM: AFG1-family ATPase; KEGG: sme:SMc02478 hypothetical protein YP_001328610.1 PFAM: outer membrane lipoprotein omp19; KEGG: sme:SMc02475 putative outer membrane lipoprotein precursor YP_001328611.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc02474 putative ATP-binding ABC transporter protein YP_001328612.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02473 putative transport system permease ABC transporter protein YP_001328613.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02472 putative transport system permease ABC transporter protein YP_001328614.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc02471 putative periplasmic binding ABC transporter protein YP_001328615.1 PFAM: ROK family protein; KEGG: sme:SMc02470 putative transcription regulator protein YP_001328616.1 PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; KEGG: sme:SMc02469 putative oxidoreductase protein YP_001328617.1 KEGG: sme:SMc02468 hypothetical protein YP_001328619.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A; KEGG: sme:SMc02467 probable peptide methionine sulfoxide reductase protein YP_001328620.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001328621.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001328622.1 TIGRFAM: Succinate dehydrogenase hydrophobic membrane anchor; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sme:SMc02464 probable succinate dehydrogenase membrane anchor subunit protein YP_001328623.1 TIGRFAM: Succinate dehydrogenase cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sme:SMc02463 probable succinate dehydrogenase cytochrome B-556 subunit transmembrane protein YP_001328624.1 KEGG: sme:SMc03225 hypothetical/unknown protein YP_001328625.1 KEGG: sme:SMc03226 hypothetical protein YP_001328626.1 PFAM: protein of unknown function DUF55; KEGG: sme:SMc03227 hypothetical protein YP_001328627.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001328628.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001328629.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001328630.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001328631.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001328632.1 KEGG: sme:SMc03233 hypothetical protein YP_001328633.1 PFAM: HemY domain protein; KEGG: sme:SMc03234 hypothetical protein YP_001328634.1 PFAM: protein of unknown function DUF1332; KEGG: sme:SMc03235 hypothetical protein YP_001328635.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001328636.1 PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: sme:SMc03237 putative transport transmembrane protein YP_001328637.1 PFAM: protein of unknown function YGGT; KEGG: sme:SMc03238 hypothetical protein YP_001328638.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001328639.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc03241 hypothetical protein YP_001328640.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: sme:SMc03242 probable GTP-binding protein (tyrosine phosphorylated protein A) YP_001328641.1 PFAM: Alkaline phosphatase; KEGG: sme:SMc03243 putative alkaline phosphatase transmembrane protein YP_001328642.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: bte:BTH_I1202 transcriptional regulator, GntR family YP_001328643.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: mlo:mll5423 unknown protein YP_001328644.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mll5422 ABC transporter permease protein YP_001328645.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tth:TTC0795 amino acid ABC transporter, ATP-binding protein YP_001328646.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; KEGG: gvi:gll2601 probable aminotransferase YP_001328647.1 catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides YP_001328648.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001328649.1 KEGG: sme:SMc03746 hypothetical/unknown protein YP_001328650.1 KEGG: sme:SMc03747 hypothetical protein YP_001328651.1 KEGG: bja:bll7663 hypothetical protein YP_001328653.1 PFAM: isochorismatase hydrolase; KEGG: sme:SMb20491 hypothetical protein YP_001328654.1 KEGG: rsp:RSP_7172 hypothetical protein YP_001328655.1 TIGRFAM: esterase, PHB depolymerase family; KEGG: rsp:RSP_3990 poly (3-hydroxybutyrate ) depolymerase YP_001328656.1 KEGG: rle:RL0064 hypothetical protein YP_001328657.1 PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: rle:RL0065 putative glycosyl transferase YP_001328658.1 PFAM: Phosphoglycerate mutase; KEGG: sus:Acid_7225 phosphoglycerate mutase YP_001328659.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: rle:RL0066 putative xylulose-5-phosphate phosphoketolase YP_001328660.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_1112 alcohol dehydrogenase YP_001328661.1 PFAM: CBS domain containing protein; transport-associated; KEGG: sme:SMa0636 hypothetical protein YP_001328664.1 KEGG: sme:SMa0633 hypothetical protein YP_001328665.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sme:SMa0630 hypothetical protein YP_001328666.1 PFAM: protein of unknown function DUF1212; KEGG: lbu:LBUL_0807 hypothetical protein YP_001328667.1 PFAM: ribosomal protein L21; KEGG: sme:SMc03770 50S ribosomal protein L21 YP_001328668.1 involved in the peptidyltransferase reaction during translation YP_001328669.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc03773 hypothetical protein YP_001328670.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc03774 hypothetical protein YP_001328671.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001328672.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001328673.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001328674.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001328675.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sme:SMc03780 hypothetical protein YP_001328676.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001328677.1 PFAM: peptidase M23B; KEGG: sme:SMc03782 hypothetical signal peptide protein YP_001328678.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; KEGG: sme:SMc03783 putative carboxy-terminal processing protease precursor signal peptide protein YP_001328679.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: sme:SMc03784 hypothetical protein YP_001328680.1 hydrolyzes diadenosine polyphosphate YP_001328681.1 TIGRFAM: bacterioferritin; PFAM: Ferritin Dps family protein; KEGG: sme:SMc03786 probable bacterioferritin (BFR) (cytochrome B-1) (cytochrome B-557) protein YP_001328682.1 KEGG: sme:SMc03787 hypothetical protein YP_001328683.1 TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; KEGG: sme:SMc03788 putative DNA polymerase III alpha chain protein YP_001328684.1 KEGG: sme:SMc03789 hypothetical protein YP_001328685.1 KEGG: sme:SMc03790 hypothetical protein YP_001328686.1 PFAM: protein of unknown function DUF1025; KEGG: sme:SMc03791 hypothetical protein YP_001328687.1 KEGG: sme:SMc03792 hypothetical protein YP_001328688.1 PFAM: HpcH/HpaI aldolase; KEGG: sme:SMc03793 probable citrate lyase beta chain (citrase) (citryl-CoA lyase subunit) protein YP_001328689.1 KEGG: sme:SMc03794 hypothetical/unknown transmembrane protein YP_001328690.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001328691.1 PFAM: Endoribonuclease L-PSP; KEGG: sme:SMc03796 hypothetical protein YP_001328692.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001328693.1 PFAM: Aldose 1-epimerase; KEGG: sme:SMc03798 probable aldose 1-epimerase protein YP_001328694.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rsp:RSP_2371 3-oxoacyl-(acyl-carrier protein) reductase / short-chain dehydrogenase/reductase SDR YP_001328695.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: dge:Dgeo_2865 short-chain dehydrogenase/reductase SDR YP_001328696.1 PFAM: carbohydrate kinase FGGY; KEGG: pac:PPA2321 sugar kinase, putative xylulose kinase YP_001328697.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sil:SPO3789 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein YP_001328698.1 PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: vei:Veis_2228 alpha/beta hydrolase fold YP_001328699.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: gsu:GSU2436 dehydrogenase complex, E1 component, beta subunit YP_001328700.1 PFAM: dehydrogenase E1 component; KEGG: tte:TTE0186 Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit YP_001328701.1 PFAM: inner-membrane translocator; KEGG: vfi:VF1446 ribose transport system permease protein RbsC YP_001328702.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: hch:HCH_02469 ABC-type sugar transport system, ATPase component YP_001328703.1 KEGG: jan:Jann_2406 periplasmic binding protein/LacI transcriptional regulator YP_001328704.1 PFAM: putative sugar-binding domain protein; KEGG: vei:Veis_2010 transcriptional regulator, DeoR family YP_001328705.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sme:SMc03800 hypothetical protein YP_001328706.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sme:SMc03801 putative thioredoxin protein YP_001328707.1 PFAM: peptidase S16 lon domain protein; KEGG: sme:SMc03802 hypothetical protein YP_001328708.1 PFAM: protein of unknown function DUF343; KEGG: sme:SMc03803 hypothetical protein YP_001328709.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sme:SMc03804 putative 2-octaprenyl-6-methoxyphenol hydroxylase YP_001328710.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: sme:SMc03805 probable acyl-CoA thioesterase II protein YP_001328711.1 PFAM: nitrogen regulatory protein P-II; KEGG: sme:SMc03806 probable nitrogen regulatory protein PII 2 YP_001328712.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: sme:SMc03807 probable ammonium transporter protein YP_001328713.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sme:SMc03808 putative cell division transmembrane protein YP_001328714.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: sme:SMc03809 hypothetical protein YP_001328715.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sme:SMc03818 putative exodeoxyribonuclease III protein YP_001328716.1 PFAM: cyclic nucleotide-binding; KEGG: sme:SMc03819 hypothetical protein YP_001328717.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc03820 putative transcription regulator protein YP_001328718.1 KEGG: sme:SMc03821 hypothetical protein YP_001328719.1 PFAM: Phosphoglycerate mutase; KEGG: sme:SMc03822 hypothetical protein YP_001328720.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001328721.1 KEGG: mlo:mll4273 hypothetical protein YP_001328722.1 PFAM: regulatory protein MarR; KEGG: sme:SMc03824 putative transcription regulator protein YP_001328723.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc03825 putative transport protein YP_001328724.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001328725.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc03827 putative amino acid efflux transmembrane protein YP_001328726.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03828 putative ATP-binding ABC transporter protein YP_001328727.1 PFAM: inner-membrane translocator; KEGG: sme:SMc03829 putative transport system permease ABC transporter protein YP_001328728.1 PFAM: protein of unknown function DUF534; KEGG: sme:SMc03830 hypothetical protein YP_001328729.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; KEGG: sme:SMc03831 hypothetical protein YP_001328730.1 KEGG: sme:SMc03832 conserved hypothetical signal peptide protein YP_001328731.1 PFAM: protein of unknown function DUF1232; KEGG: sme:SMc03833 hypothetical protein YP_001328732.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001328733.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: sme:SMc03835 putative 2'-5' RNA ligase protein YP_001328734.1 PFAM: lipolytic protein G-D-S-L family; KEGG: sme:SMc03836 putative acyl-CoA thioesterase I protein YP_001328735.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03837 putative ATP-binding ABC transporter protein YP_001328736.1 PFAM: protein of unknown function DUF214; KEGG: sme:SMc03838 hypothetical transmembrane protein YP_001328737.1 PFAM: protein of unknown function UPF0005; KEGG: sme:SMc03839 hypothetical transmembrane protein YP_001328738.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc03840 putative acetyltransferase (antibiotic resistance) protein YP_001328739.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001328740.1 KEGG: sme:SMc03842 hypothetical protein YP_001328741.1 PFAM: regulatory protein ArsR; KEGG: sme:SMc03843 putative transcription regulator protein YP_001328742.1 KEGG: sme:SMc03844 hypothetical protein YP_001328743.1 PFAM: protein of unknown function DUF1223; KEGG: sme:SMc03845 hypothetical protein YP_001328744.1 Catalyzes the conversion of citrate to isocitrate YP_001328745.1 ATP-binding protein; required for proper cytochrome c maturation YP_001328746.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: sme:SMc03848 putative heme exporter B (cytochrome C-type biogenesis protein) transmembrane YP_001328747.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: sme:SMc03849 putative heme exporter C (cytochrome C-type biogenesis protein) transmembrane YP_001328748.1 PFAM: Heme exporter protein D (CcmD); KEGG: sme:SMc03850 putative heme exporter D (cytochrome c-type biogenesis protein) transmembrane YP_001328749.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sme:SMc03851 putative thiol:disulfide interchange protein (cytochrome C biogenesis protein) YP_001328750.1 KEGG: sme:SMc03852 hypothetical protein YP_001328751.1 Involved in cell division; probably involved in intracellular septation YP_001328752.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; KEGG: sme:SMc03854 putative cell division protein YP_001328753.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; KEGG: sme:SMc03855 hypothetical protein YP_001328754.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001328755.1 KEGG: atc:AGR_C_4888 hypothetical protein YP_001328756.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; KEGG: sme:SMc03857 probable signal recognition particle protein (fifty-four homolog) YP_001328757.1 catalyzes the interconversion of chorismate to prephenate YP_001328758.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001328759.1 Essential for efficient processing of 16S rRNA YP_001328760.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001328761.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMc03862 hypothetical transmembrane protein YP_001328762.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001328763.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: sme:SMc03864 putative amino acid-binding periplasmic (signal peptide) ABC transporter protein YP_001328764.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03865 putative amino-acid transport system permease ABC transporter protein YP_001328765.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03866 putative ATP-binding ABC transporter protein YP_001328766.1 TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: sme:SMc03867 hypothetical protein YP_001328767.1 KEGG: sme:SMc03868 hypothetical protein YP_001328768.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001328769.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001328770.1 TIGRFAM: ABC transporter, ATPase subunit, ThiQ subfamily; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03871 putative ATP-binding ABC transporter protein YP_001328771.1 PFAM: peptidase M48 Ste24p; KEGG: sme:SMc03872 hypothetical protein YP_001328772.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production YP_001328773.1 PFAM: transcription factor CarD; KEGG: sme:SMc03874 CarD family transcriptional regulator YP_001328774.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sme:SMc03875 putative ferredoxin protein YP_001328775.1 PFAM: RNA-binding S4 domain protein; KEGG: sme:SMc03876 hypothetical heat shock-like protein YP_001328776.1 PFAM: helicase domain protein; KEGG: sme:SMc03877 hypothetical protein YP_001328777.1 TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc03878 acetoacetyl-CoA reductase protein YP_001328778.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001328779.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein; KEGG: sme:SMc03880 hypothetical protein YP_001328780.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001328781.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc03882 putative glutathione S-transferase protein YP_001328782.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001328783.1 PFAM: Polyprenyl synthetase; KEGG: sme:SMc03884 probable geranyltranstransferase protein YP_001328784.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001328785.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: atc:AGR_C_3482 short chain dehydrogenase YP_001328786.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_C_3484 ribose ABC transporter (ATP-binding protein) YP_001328787.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_C_3486 bifunctional carbohydrate binding and transport protein YP_001328788.1 PFAM: inner-membrane translocator; KEGG: atc:AGR_C_3488 bifunctional carbohydrate binding and transport protein YP_001328789.1 PFAM: Transketolase domain protein; KEGG: rle:RL2719 putative ferredoxin YP_001328790.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: ret:RHE_CH02397 transketolase C-terminal subunit protein YP_001328791.1 PFAM: carbohydrate kinase FGGY; KEGG: atc:AGR_C_3493 glycerol kinase YP_001328792.1 PFAM: putative sugar-binding domain protein; KEGG: ret:RHE_CH02395 probable transcriptional regulator protein YP_001328793.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: atc:AGR_C_3496 hypothetical protein YP_001328794.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001328795.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc03889 putative transport protein YP_001328796.1 PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: sme:SMc03890 putative transcription regulator protein YP_001328797.1 PFAM: extracellular solute-binding protein family 3; KEGG: sme:SMc03891 putative amino acid-binding periplasmic ABC transporter protein YP_001328798.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc03893 putative amino-acid transport system permease ABC transporter protein YP_001328799.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc03894 putative amino-acid ABC transporter ATP-binding protein YP_001328800.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001328801.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: sme:SMc03896 putative transcription regulator protein YP_001328803.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA YP_001328804.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pol:Bpro_2210 transcriptional regulator, GntR family YP_001328805.1 PFAM: sulfatase; KEGG: ppu:PP_0077 choline sulfatase YP_001328806.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; NMT1/THI5 like domain protein; KEGG: bsu:BG10656 aliphatic sulfonates transport system substrate-binding protein YP_001328807.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mac:MA0063 sulfonate ABC transporter, ATP-binding protein YP_001328809.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mta:Moth_1974 binding-protein-dependent transport systems inner membrane component YP_001328810.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pst:PSPTO_5321 taurine ABC transporter, permease protein YP_001328811.1 PFAM: aldo/keto reductase; KEGG: sma:SAV7284 oxidoreductase YP_001328812.1 PFAM: amidohydrolase 2; KEGG: pol:Bpro_2213 amidohydrolase 2 YP_001328813.1 KEGG: sme:SMc04381 hypothetical protein YP_001328814.1 PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: sme:SMc04382 beta-(1,2)-glucan production associated transmembrane protein YP_001328815.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc04882 probable transcription regulator protein YP_001328816.1 PFAM: protein of unknown function DUF1338; KEGG: sme:SMc04383 hypothetical protein YP_001328817.1 PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc04384 putative oxidoreductase protein YP_001328818.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc04385 putative aldehyde dehydrogenase transmembrane protein YP_001328819.1 PFAM: aminotransferase class I and II; KEGG: sme:SMc04386 aspartate aminotransferase B protein YP_001328820.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: sme:SMc04387 putative aldehyde dehydrogenase protein YP_001328821.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001328822.1 PFAM: MOFRL domain protein; KEGG: sme:SMc04389 putative hydroxypyruvate reductase protein YP_001328823.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: sme:SMc04390 putative L-sorbose dehydrogenase, FAD dependent protein YP_001328824.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001328825.1 KEGG: sme:SMc04392 putative dehydrogenase transmembrane protein YP_001328826.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc04393 putative ATP-binding ABC transporter protein YP_001328827.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04394 putative transport system permease ABC transporter protein YP_001328828.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04395 putative transport system permease ABC transporter protein YP_001328829.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc04396 putative periplasmic binding protein YP_001328830.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc04397 putative L-sorbosone dehydrogenase, NADP dependent protein YP_001328831.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sme:SMc04398 putative enoyl-CoA hydratase protein YP_001328832.1 PFAM: coenzyme A transferase; KEGG: sme:SMc04399 putative acyl-CoA transferase protein YP_001328833.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc04400 putative oxidoreductase protein YP_001328834.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMc04401 putative transcription regulator protein YP_001328835.1 PFAM: protein of unknown function DUF993; KEGG: sme:SMc04402 hypothetical protein YP_001328836.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: sme:SMc04403 probable peptidyl-dipeptidase A protein YP_001328837.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001328838.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sme:SMc04406 hypothetical protein YP_001328839.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sme:SMc04407 putative transport transmembrane protein YP_001328840.1 KEGG: sme:SMc04409 hypothetical protein YP_001328841.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001328842.1 TIGRFAM: lytic murein transglycosylase; KEGG: sme:SMc04411 putative membrane-bound lytic murein transglycosylase signal peptide protein YP_001328843.1 KEGG: nha:Nham_4172 ISSpo6, transposase orf A YP_001328844.1 PFAM: carbonic anhydrase; KEGG: sme:SMc04083 putative carbonic anhydrase protein YP_001328845.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001328846.1 PFAM: NAD-glutamate dehydrogenase; KEGG: sme:SMc04085 hypothetical protein YP_001328847.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc04087 putative transmembrane protein YP_001328848.1 involved in de novo purine biosynthesis YP_001328849.1 PFAM: Heparinase II/III family protein; KEGG: sme:SMc04089 hypothetical protein YP_001328850.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: sme:SMc04090 hypothetical SUN protein YP_001328851.1 putative metalloprotease YP_001328852.1 PFAM: protein of unknown function DUF1674; KEGG: sme:SMc04092 hypothetical protein YP_001328853.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001328854.1 PFAM: protein of unknown function DUF1013; KEGG: sme:SMc04094 hypothetical protein YP_001328855.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc04095 putative acyl-CoA synthetase protein YP_001328856.1 PFAM: alanine racemase domain protein; KEGG: sme:SMc02812 hypothetical protein YP_001328857.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001328858.1 KEGG: sme:SMc02803 hypothetical protein YP_001328859.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001328860.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: sme:SMc02801 probable chromosome partitioning protein PARB YP_001328861.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sme:SMc02800 probable chromosome partitioning protein PARA YP_001328862.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001328863.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001328864.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001328865.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001328866.1 PFAM: conserved hypothetical protein 701; KEGG: sme:SMc02795 hypothetical protein YP_001328867.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001328868.1 PFAM: protein of unknown function DUF299; KEGG: sme:SMc02793 hypothetical protein YP_001328869.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001328870.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001328871.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001328872.1 3'-5' exonuclease of DNA polymerase III YP_001328873.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001328874.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: sme:SMc02787 hypothetical transmembrane protein YP_001328875.1 PFAM: import inner membrane translocase subunit Tim44; KEGG: sme:SMc02786 putative translocase transmembrane protein YP_001328876.1 PFAM: MltA domain protein; 3D domain protein; KEGG: sme:SMc02785 putative lytic murein transglycosylase A protein YP_001328877.1 PFAM: Smr protein/MutS2; KEGG: sme:SMc02784 hypothetical protein YP_001328878.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMc02783 hypothetical protein YP_001328879.1 negatively supercoils closed circular double-stranded DNA YP_001328880.1 PFAM: nitroreductase; KEGG: sme:SMc02781 putative oxidoreductase protein YP_001328881.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sme:SMc02780 probable succinate-semialdehyde dehydrogenase [NADP+] protein YP_001328882.1 PFAM: HpcH/HpaI aldolase; KEGG: sme:SMc02778 putative hydroxyacid aldolase protein YP_001328883.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc02777 putative transcription regulator protein YP_001328884.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: sme:SMc02776 putative altronate hydrolase protein YP_001328885.1 PFAM: aldo/keto reductase; KEGG: sme:SMc02775 putative L-fucose dehydrogenase (D-threo aldose 1-dehydrogenase) protein YP_001328886.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMc02774 putative ABC transporter periplasmic binding protein YP_001328887.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02773 putative ABC transporter ATP-binding protein YP_001328888.1 PFAM: inner-membrane translocator; KEGG: sme:SMc02772 putative sugar ABC transporter permease protein YP_001328889.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc02771 putative zinc-type alcohol dehydrogenase protein YP_001328890.1 PFAM: plasmid stabilization system; KEGG: sme:SMa0473 hypothetical protein YP_001328891.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: nha:Nham_4666 RelB antitoxin YP_001328892.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: sme:SMc02770 hypothetical protein YP_001328893.1 KEGG: sme:SMc02769 hypothetical protein YP_001328894.1 PFAM: protein of unknown function DUF45; KEGG: sme:SMc02768 hypothetical protein YP_001328895.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001328896.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001328897.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001328898.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001328899.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: sme:SMc02763 probable folc bifunctional protein (folylpolyglutamate synthase / dihydrofolate synthase) YP_001328900.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sme:SMc02761 probable thioredoxin protein YP_001328901.1 TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: sme:SMc02760 putative ATP-dependent nuclease/helicase protein YP_001328902.1 TIGRFAM: Double-strand break repair protein AddB; KEGG: sme:SMc02759 hypothetical protein YP_001328903.1 PFAM: Nucleotidyl transferase; KEGG: sme:SMc02758 putative nucleotidyl transferase protein YP_001328904.1 PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: sme:SMc02757 hypothetical protein YP_001328905.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02756 putative sensor histidine kinase protein YP_001328906.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001328907.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: sme:SMc02754 putative phosphocarrier HPR transmembrane protein YP_001328908.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sme:SMc02753 putative IIA component of PTS system protein YP_001328909.1 KEGG: sme:SMc02752 hypothetical protein YP_001328910.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sme:SMc04446 histidine kinase sensory transmembrane protein YP_001328911.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMc02560 transcriptional regulatory protein YP_001328912.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001328913.1 PFAM: Class I peptide chain release factor; KEGG: sme:SMc02563 hypothetical protein YP_001328914.1 PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: sme:SMc02564 hypothetical protein YP_001328915.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: sme:SMc02566 probable DNA repair system specific for alkylated DNA protein YP_001328916.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001328917.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001328918.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001328919.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001328920.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001328921.1 KEGG: sme:SMc02573 hypothetical protein YP_001328922.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001328923.1 heat shock protein involved in degradation of misfolded proteins YP_001328924.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein YP_001328925.1 heat shock protein involved in degradation of misfolded proteins YP_001328926.1 PFAM: protein of unknown function DUF1402; KEGG: sme:SMc02578 hypothetical protein YP_001328927.1 PFAM: cytochrome P450; KEGG: sme:SMc02579 putative cytochrome P450 monooxygenase protein YP_001328928.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: sme:SMc02580 hypothetical protein YP_001328929.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001328930.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sme:SMc02582 hypothetical protein YP_001328931.1 PFAM: protein of unknown function DUF1052; KEGG: sme:SMc02583 hypothetical protein YP_001328932.1 PFAM: response regulator receiver; KEGG: sme:SMc02584 transcription regulator protein YP_001328933.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02585 sensor histidine kinase transmembrane protein YP_001328934.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases; KEGG: sme:SMc02586 ATP-dependent helicase protein YP_001328935.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02587 putative ATP-binding ABC transporter protein YP_001328936.1 KEGG: sme:SMc02588 putative permease ABC transporter protein YP_001328937.1 KEGG: sme:SMc02589 conserved hypothetical protein YP_001328938.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: sit:TM1040_3231 periplasmic sensor hybrid histidine kinase YP_001328939.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sit:TM1040_3232 two component transcriptional regulator, winged helix family YP_001328940.1 PFAM: extracellular solute-binding protein family 1; KEGG: rde:RD1_1059 iron ABC transporter iron-binding protein, putative YP_001328941.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bmb:BruAb2_0512 ABC transporter, ATP-binding protein YP_001328943.1 PFAM: Sarcosine oxidase gamma subunit; KEGG: sme:SMc02605 putative sarcosine oxidase gamma subunit protein YP_001328944.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc02606 putative sarcosine oxidase alpha subunit transmembrane protein YP_001328945.1 TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: sme:SMc02607 sarcosine oxidase delta subunit protein YP_001328946.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: sme:SMc02608 sarcosine oxidase beta subunit protein YP_001328947.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: sme:SMc02609 putative transcription regulator protein YP_001328948.1 PFAM: glutamine amidotransferase class-II; KEGG: sme:SMc02610 putative amidotransferase protein YP_001328949.1 PFAM: glutamate synthase alpha subunit domain protein; KEGG: sme:SMc02611 putative oxidoreductase protein YP_001328950.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: sme:SMc02612 putative oxidoreductase protein YP_001328951.1 PFAM: glutamine synthetase catalytic region; KEGG: sme:SMc02613 glutamine synthetase III protein YP_001328952.1 KEGG: sme:SMc02614 hypothetical protein YP_001328953.1 KEGG: sme:SMc02615 hypothetical signal peptide protein YP_001328954.1 PFAM: amino acid permease-associated region; KEGG: sme:SMc02616 putative permease transmembrane protein YP_001328955.1 KEGG: sme:SMc02617 hypothetical protein YP_001328956.1 KEGG: sme:SMc02618 hypothetical protein YP_001328957.1 KEGG: sme:SMc02619 hypothetical protein YP_001328958.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: sme:SMc02620 hypothetical protein YP_001328959.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: ttj:TTHA0473 peptide ABC transporter, ATP-binding protein YP_001328960.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: dge:Dgeo_1341 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like protein YP_001328961.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpa:RPA1472 putative dipeptide transport permease protein YP_001328962.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ecs:ECs2089 putative transport protein YP_001328963.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: nca:Noca_0080 5-oxoprolinase (ATP-hydrolyzing) YP_001328964.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: nca:Noca_0079 5-oxoprolinase (ATP-hydrolyzing) YP_001328965.1 PFAM: extracellular solute-binding protein family 5; KEGG: ecs:ECs2091 putative hemin-binding lipoprotein YP_001328966.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: rfr:Rfer_3227 transcriptional regulator, XRE family with cupin sensor domain YP_001328967.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001328968.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rle:pRL110552 putative aminomethyltransferase/glycine cleavage protein YP_001328969.1 KEGG: sme:SMc04152 hypothetical protein YP_001328970.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMc04151 putative ferredoxin protein YP_001328971.1 KEGG: sme:SMc04150 hypothetical protein YP_001328972.1 PFAM: flavin-containing monooxygenase FMO; KEGG: sme:SMc04149 putative oxidoreductase protein YP_001328973.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc04148 putative aminomethyltransferase protein YP_001328974.1 PFAM: amino acid permease-associated region; KEGG: sme:SMc04147 putative permease protein YP_001328975.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sme:SMc04145 hypothetical protein YP_001328976.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001328977.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sme:SMc04143 putative transcription regulator protein YP_001328978.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: sme:SMc04142 hypothetical protein YP_001328979.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc04141 putative glutathione S-transferase protein YP_001328980.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc04140 putative ATP-binding ABC transporter protein YP_001328981.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc04139 putative oxidoreductase protein YP_001328982.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc04138 putative oxidoreductase protein YP_001328983.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04137 putative transport system permease ABC transporter protein YP_001328984.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc04136 putative transport system permease ABC transporter protein YP_001328985.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc04135 putative periplasmic binding ABC transporter protein YP_001328986.1 PFAM: regulatory protein TetR; KEGG: sme:SMc04134 putative transcription regulator protein YP_001328987.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc04133 putative oxidoreductase protein YP_001328988.1 PFAM: protein of unknown function DUF993; KEGG: sme:SMc04132 hypothetical protein YP_001328989.1 KEGG: sme:SMc04131 hypothetical protein YP_001328990.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc04130 hypothetical protein YP_001328991.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; homoserine dehydrogenase NAD-binding; KEGG: sme:SMc04129 putative oxidoreductase protein YP_001328992.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sme:SMc04128 putative heavy metal transporting ATPase protein YP_001328993.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc04127 putative ATP-binding ABC transporter protein YP_001328994.1 PFAM: inner-membrane translocator; KEGG: sme:SMc04126 putative transport system permease ABC transporter protein YP_001328995.1 PFAM: inner-membrane translocator; KEGG: sme:SMc04125 putative transport system permease ABC transporter protein YP_001328996.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001328997.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001328998.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001328999.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001329000.1 catalyzes the formation of inosine from adenosine YP_001329001.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001329002.1 KEGG: sme:SMc04118 hypothetical protein YP_001329003.1 PFAM: TadE family protein; KEGG: sme:SMc04117 hypothetical protein YP_001329004.1 KEGG: sme:SMc04115 hypothetical protein YP_001329005.1 PFAM: Flp/Fap pilin component; KEGG: sme:SMc04114 putative pilin subunit protein YP_001329006.1 PFAM: peptidase A24A prepilin type IV; KEGG: sme:SMc04113 prepilin peptidase CpaA YP_001329007.1 PFAM: SAF domain protein; KEGG: sme:SMc04112 putative pilus assembly signal peptide protein YP_001329008.1 PFAM: type II and III secretion system protein; transport-associated; KEGG: sme:SMc04111 putative pilus assembly transmembrane protein YP_001329009.1 TIGRFAM: pilus (Caulobacter type) biogenesis lipoprotein CpaD; KEGG: sme:SMc04110 pilus assembly protein cpaD YP_001329010.1 KEGG: sme:SMc04109 putative response regulator protein YP_001329011.1 PFAM: type II secretion system protein E; KEGG: sme:SMc02820 putative pilus assembly protein YP_001329012.1 PFAM: type II secretion system protein; KEGG: sme:SMc02821 hypothetical protein YP_001329013.1 PFAM: type II secretion system protein; KEGG: sme:SMc02822 hypothetical protein YP_001329014.1 PFAM: Tetratricopeptide TPR_4; KEGG: sme:SMc02824 hypothetical protein YP_001329015.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: sme:SMc02825 putative aminopeptidase protein YP_001329016.1 PFAM: regulatory protein MarR; KEGG: sme:SMc02826 putative transcription regulator protein YP_001329017.1 PFAM: NLP/P60 protein; KEGG: sme:SMc02827 hypothetical protein YP_001329018.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc02828 putative hydroxyacid dehydrogenase protein YP_001329019.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: sme:SMc02829 putative ATP-binding ABC transporter protein YP_001329020.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02830 putative permease ABC transporter protein YP_001329021.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02831 putative permease ABC transporter protein YP_001329022.1 PFAM: extracellular solute-binding protein family 5; KEGG: sme:SMc02832 putative periplasmic binding protein YP_001329023.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001329024.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001329025.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001329026.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02836 putative ATP-binding ABC transporter protein YP_001329027.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001329028.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001329029.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: sme:SMc02841 putative methylated-DNA--protein-cysteine methyltransferase transcription regulator YP_001329030.1 KEGG: sme:SMc02842 hypothetical protein YP_001329031.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sme:SMc02843 probable endonuclease III protein YP_001329032.1 PFAM: regulatory protein TetR; KEGG: sme:SMc02844 putative transcription regulator protein YP_001329033.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc02845 putative antibiotic resistance protein YP_001329034.1 PFAM: PfkB domain protein; KEGG: sme:SMc02846 putative sugar kinase protein YP_001329035.1 PFAM: protein of unknown function DUF1058; SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: sme:SMc02848 hypothetical protein YP_001329036.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc02849 2-hydroxyacid dehydrogenase YP_001329037.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001329038.1 PFAM: regulatory protein MarR; KEGG: sme:SMc02851 putative transcription regulator protein YP_001329039.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sme:SMc02852 hypothetical protein YP_001329040.1 KEGG: sme:SMc02853 hypothetical transmembrane protein YP_001329041.1 KEGG: sme:SMc02854 hypothetical signal peptide protein YP_001329042.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc02855 hypothetical protein YP_001329043.1 PFAM: Pyrimidine dimer DNA glycosylase; KEGG: bmb:BruAb2_0604 endonuclease V YP_001329044.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sme:SMc02856 putative penicillin-binding protein YP_001329045.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001329046.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001329047.1 KEGG: sme:SMc02859 hypothetical protein YP_001329048.1 PFAM: protein of unknown function DUF1326; KEGG: sme:SMc02860 hypothetical protein YP_001329049.1 PFAM: phosphate transporter; KEGG: sme:SMc02861 phosphate transport transmembrane protein YP_001329050.1 PFAM: protein of unknown function DUF47; KEGG: sme:SMc02862 PIT accessory protein YP_001329051.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001329052.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001329053.1 PFAM: regulatory protein TetR; Tetracycline transcriptional repressor MAATS-type domain protein; KEGG: sme:SMc02866 putative transcription regulator protein YP_001329054.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sme:SMc02867 putative multidrug-efflux system transmembrane protein YP_001329055.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc02868 putative multidrug efflux system protein YP_001329056.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc02869 putative ATP-binding ABC transporter protein YP_001329057.1 PFAM: oxidoreductase domain protein; KEGG: sme:SMc02870 putative oxidoreductase protein YP_001329058.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02871 putative permease ABC transporter protein YP_001329059.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02872 putative permease ABC transporter protein YP_001329061.1 PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMc02873 putative periplasmic binding (signal peptide) ABC transporter protein YP_001329062.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001329063.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sme:SMc02875 hypothetical protein YP_001329064.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMc02876 putative transcription regulator protein YP_001329065.1 PFAM: sugar isomerase (SIS); KEGG: sme:SMc02877 putative glucosamine-6-phosphate isomerase YP_001329066.1 TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: sme:SMc02878 probable N-acetylglucosamine-6-phosphate deacetylase protein YP_001329067.1 PFAM: CutC family protein; KEGG: sme:SMc02879 copper homeostasis protein YP_001329068.1 PFAM: ROK family protein; KEGG: sme:SMc02880 hypothetical protein YP_001329069.1 PFAM: Amidase; KEGG: sme:SMc02881 putative amidase protein YP_001329070.1 putative role in sulfur assimilation YP_001329071.1 PFAM: SlyX family protein; KEGG: sme:SMc02883 slyX protein, putative YP_001329072.1 PFAM: basic membrane lipoprotein; KEGG: sme:SMc02884 putative lipoprotein PRECURSOR YP_001329073.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001329074.1 KEGG: sme:SMc02886 conserved hypothetical signal peptide protein YP_001329075.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc02893 putative transcription regulator protein YP_001329076.1 PFAM: transport-associated; KEGG: sme:SMc02894 hypothetical protein YP_001329077.1 PFAM: Auxin Efflux Carrier; KEGG: sme:SMc02895 hypothetical transmembrane protein YP_001329078.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001329079.1 PFAM: cytochrome c class I; KEGG: sme:SMc02897 putative cytochrome c transmembrane protein YP_001329080.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001329081.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001329082.1 PFAM: protein of unknown function DUF1127; KEGG: sme:SMc02900 hypothetical protein YP_001329083.1 PFAM: NUDIX hydrolase; NADH pyrophosphatase-like ; Zinc ribbon NADH pyrophosphatase; KEGG: sme:SMc02903 putative NADH pyrophosphatase YP_001329084.1 PFAM: histidine triad (HIT) protein; KEGG: sme:SMc02904 hypothetical protein YP_001329085.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001329086.1 PFAM: conserved hypothetical protein 103; KEGG: sme:SMc02906 conserved hypothetical protein YP_001329087.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc02907 putative amino acid efflux transmembrane protein YP_001329088.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001329089.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMc02909 putative transglycosylase transmembrane protein YP_001329090.1 PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: sme:SMc02910 putative transport transmembrane protein YP_001329091.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001329092.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001329093.1 PFAM: protein of unknown function DUF448; KEGG: sme:SMc02913 hypothetical protein YP_001329094.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001329095.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001329096.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001329097.1 PFAM: HWE histidine kinase; KEGG: sme:SMc00322 hypothetical protein YP_001329098.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001329099.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; SMART: KH domain protein; KEGG: sme:SMc00324 probable polyribonucleotide nucleotidyltransferase protein YP_001329100.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: sme:SMc00325 hypothetical protein YP_001329101.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001329102.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001329103.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001329104.1 PFAM: ferric-uptake regulator; KEGG: sme:SMc00329 putative iron response regulator protein YP_001329105.1 PFAM: protein of unknown function UPF0126; KEGG: sme:SMc00330 putative transmembrane protein YP_001329106.1 PFAM: protein of unknown function DUF218; KEGG: sme:SMc00331 hypothetical protein YP_001329108.1 KEGG: sme:SMc00332 hypothetical protein YP_001329109.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001329110.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001329111.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001329112.1 KEGG: sme:SMc00336 hypothetical protein YP_001329113.1 KEGG: sme:SMc00337 hypothetical/unknown protein YP_001329114.1 KEGG: sme:SMc00338 hypothetical protein YP_001329115.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; KEGG: sme:SMc00339 adenylate cyclase 1 protein YP_001329116.1 KEGG: sme:SMc00341 hypothetical protein YP_001329117.1 PFAM: 3'-5' exonuclease; KEGG: sme:SMc00342 ribonuclease D YP_001329118.1 TIGRFAM: conserved hypothetical selenoprotein; PFAM: Selenoprotein W-related; KEGG: sme:SMc00345 selenoprotein W-related protein YP_001329119.1 PFAM: DoxX family protein; KEGG: sme:SMc00346 hypothetical protein YP_001329120.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001329121.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: mmr:Mmar10_0575 glutathione-dependent formaldehyde-activating, GFA YP_001329122.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001329123.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00350 putative transport transmembrane protein YP_001329124.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: sme:SMc00351 hypothetical protein YP_001329125.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00352 putative acetyltransferase protein YP_001329126.1 PFAM: Exopolysaccharide synthesis ExoD; KEGG: sme:SMc00353 putative transmembrane protein YP_001329128.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: sme:SMc00354 hypothetical protein YP_001329129.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: sme:SMc00355 lysine 2,3-aminomutase YP_001329130.1 PFAM: tRNA synthetase class II (D K and N); KEGG: sme:SMc00356 putative lysyl-tRNA synthetase protein YP_001329131.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001329132.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMc00358 putative cyclopropane-fatty-acyl-phospholipid synthase protein YP_001329133.1 PFAM: Rubrerythrin; protein of unknown function DUF125 transmembrane; KEGG: sme:SMc00359 hypothetical protein YP_001329134.1 PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: sme:SMc00360 hypothetical protein YP_001329135.1 KEGG: sme:SMc00361 hypothetical protein YP_001329136.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001329137.1 PFAM: ribosomal protein L35; KEGG: sme:SMc00363 50S ribosomal protein L35 YP_001329138.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001329139.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001329140.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001329141.1 KEGG: sme:SMc00367 hypothetical protein YP_001329142.1 PFAM: aldo/keto reductase; KEGG: rle:RL0272 putative aldo-keto reductase/oxidoreductase YP_001329143.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sme:SMc00370 putative transcription regulator protein YP_001329144.1 PFAM: protein of unknown function DUF892; KEGG: sme:SMc00371 hypothetical protein YP_001329145.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc00372 short chain dehydrogenase YP_001329146.1 KEGG: sme:SMc00373 hypothetical/unknown protein YP_001329147.1 PFAM: aldo/keto reductase; KEGG: sme:SMc00374 putative oxidoreductase transmembrane protein YP_001329148.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc00375 putative oxidoreductase protein YP_001329149.1 KEGG: sme:SMc00376 hypothetical protein YP_001329150.1 PFAM: helix-turn-helix domain protein; KEGG: sme:SMc00377 hypothetical protein YP_001329151.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001329152.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: sme:SMc00379 putative oxidoreductase protein YP_001329153.1 PFAM: regulatory protein MarR; KEGG: sme:SMc00380 putative transcription regulator protein YP_001329154.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00381 hypothetical protein YP_001329155.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein YP_001329156.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eli:ELI_09040 hypothetical protein YP_001329157.1 PFAM: peptidase M29 aminopeptidase II; KEGG: sme:SMc00382 probable aminopeptidase protein YP_001329158.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00383 putative glutathione S-transferase protein YP_001329159.1 PFAM: regulatory protein MarR; KEGG: sme:SMc00384 putative transcription regulation protein YP_001329160.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sme:SMc00385 hypothetical protein YP_001329161.1 PFAM: arsenate reductase and related; KEGG: sme:SMc00386 hypothetical protein YP_001329162.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001329163.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: sme:SMc00388 hypothetical protein YP_001329164.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: ret:RHE_CH01077 hypothetical protein YP_001329165.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: ret:RHE_CH01078 hypothetical protein YP_001329166.1 PFAM: regulatory protein ArsR; KEGG: ret:RHE_CH01079 probable transcriptional regulator protein, ArsR family YP_001329167.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: sme:SMc01712 putative L-lactate dehydrogenase (cytochrome) protein YP_001329168.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001329169.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001329170.1 PFAM: thioesterase superfamily protein; KEGG: sme:SMc00396 hypothetical protein YP_001329171.1 PFAM: TspO/MBR family protein; KEGG: atc:AGR_C_485 mitochondrial benzodiazepine receptor/sensory transduction protein YP_001329172.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc00397 hypothetical protein YP_001329173.1 PFAM: uncharacterised conserved protein UCP028101; KEGG: sme:SMc00460 hypothetical protein YP_001329174.1 PFAM: surface antigen variable number repeat protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: mag:amb3772 hemolysin activation/secretion protein YP_001329175.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; KEGG: mag:amb3773 large exoprotein involved in heme utilization or adhesion YP_001329176.1 SMART: Parallel beta-helix repeat; Integrin alpha beta-propellor repeat protein; KEGG: dps:DP1520 hypothetical protein YP_001329177.1 PFAM: Invasion associated locus B family protein; KEGG: mlo:mll2844 invasion-like protein YP_001329178.1 KEGG: sme:SMc00400 hypothetical signal peptide protein YP_001329179.1 PFAM: protein of unknown function DUF1111; KEGG: sme:SMc00401 hypothetical protein YP_001329180.1 KEGG: sme:SMc00402 putative iron-regulated protein YP_001329181.1 PFAM: Fmu (Sun) domain protein; KEGG: sme:SMc00403 hypothetical NOL1/NOP2/SUN family signature protein YP_001329182.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: sme:SMc00404 putative rare lipoprotein A YP_001329184.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: sme:SMc00405 hypothetical protein YP_001329185.1 PFAM: HEAT domain containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: sme:SMc00406 hypothetical 4FE-4S ferredoxins, iron-sulfur binding region signature protein YP_001329186.1 PFAM: Glutathione S-transferase domain; KEGG: sme:SMc00407 putative glutathione S-transferase protein YP_001329187.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001329188.1 KEGG: sme:SMc00409 hypothetical signal peptide protein YP_001329189.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: sme:SMc00410 putative oxidoreductase protein YP_001329190.1 PFAM: protein of unknown function DUF1330; KEGG: sme:SMc00411 hypothetical protein YP_001329191.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001329192.1 PFAM: Phosphoglycerate mutase; KEGG: sme:SMc00413 hypothetical protein YP_001329193.1 KEGG: sme:SMc00414 hypothetical protein YP_001329194.1 binds the polymerase to DNA and acts as a sliding clamp YP_001329195.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sme:SMc00416 hypothetical protein YP_001329196.1 PFAM: protein of unknown function UPF0102; KEGG: sme:SMc00418 predicted endonuclease YP_001329197.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001329198.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sme:SMc00420 magnesium chelatase family protein YP_001329199.1 PFAM: SH3 domain protein; Variant SH3 domain protein; KEGG: bca:BCE_3400 SH3 domain protein YP_001329200.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sme:SMc00421 probable cysteine synthase A (O-acetylserine sulfhydrylase A) protein YP_001329201.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sme:SMc00423 putative amino acid efflux protein YP_001329202.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00424 hypothetical protein YP_001329203.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sme:SMc00425 putative transcription regulator protein YP_001329204.1 catalyzes the formation of dUMP from dUTP YP_001329205.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: sme:SMc00427 peptide chain release factor RF-3 YP_001329206.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sme:SMc00428 putative transmembrane protein YP_001329207.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: sme:SMc00429 putative transcription regulator protein YP_001329208.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: sme:SMc00431 hypothetical protein YP_001329209.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sme:SMc00432 putative myo-inositol catabolism protein YP_001329210.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sme:SMc00433 putative myo-inositoL catabolism protein YP_001329211.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sme:SMc01166 putative malonic semialdehyde oxidative decarboxylase protein YP_001329212.1 PFAM: PfkB domain protein; KEGG: sme:SMc01165 putative sugar kinase protein YP_001329213.1 PFAM: sugar isomerase (SIS); KEGG: sme:SMc01164 hypothetical protein YP_001329214.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sme:SMc01163 putative oxidoreductase protein YP_001329215.1 KEGG: sme:SMc01162 hypothetical protein YP_001329216.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001329217.1 PFAM: protein of unknown function UPF0074; Helix-turn-helix type 11 domain protein; KEGG: sme:SMc01160 hypothetical protein YP_001329218.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMc01159 putative oxidoreductase protein YP_001329219.1 PFAM: Ankyrin; KEGG: sme:SMc01158 hypothetical protein YP_001329220.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc01157 3-oxoacyl-[acyl-carrier protein] reductase YP_001329221.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: sme:SMc01156 probable ubiquinone biosynthesis protein YP_001329222.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001329223.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001329224.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA