-- dump date   	20120504_162613
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
553482000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
553482000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000003	Walker A motif; other site
553482000004	ATP binding site [chemical binding]; other site
553482000005	Walker B motif; other site
553482000006	arginine finger; other site
553482000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
553482000008	DnaA box-binding interface [nucleotide binding]; other site
553482000009	HMMPfam hit to PF00308, Bacterial dnaA protein, score 6.5e-116
553482000010	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000011	HMMPfam hit to PF08299, Bacterial dnaA protein helix-turn-helix, score 7.6e-36
553482000012	PS01008 DnaA protein signature.
553482000013	DNA polymerase III subunit beta; Validated; Region: PRK05643
553482000014	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
553482000015	putative DNA binding surface [nucleotide binding]; other site
553482000016	dimer interface [polypeptide binding]; other site
553482000017	beta-clamp/clamp loader binding surface; other site
553482000018	beta-clamp/translesion DNA polymerase binding surface; other site
553482000019	HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-te, score 1.9e-25
553482000020	HMMPfam hit to PF02767, DNA polymerase III beta subunit, cent, score 8e-32
553482000021	HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-te, score 2.9e-30
553482000022	Bacterial protein of unknown function (DUF951); Region: DUF951; cl01864
553482000023	HMMPfam hit to PF06107, Bacterial protein of unknown function (DUF95, score 1.5e-44
553482000024	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000025	non-specific DNA binding site [nucleotide binding]; other site
553482000026	salt bridge; other site
553482000027	sequence-specific DNA binding site [nucleotide binding]; other site
553482000028	HMMPfam hit to PF01381, Helix-turn-helix, score 2.8e-18
553482000029	Predicted helix-turn-helix motif with score 2169.000, SD 6.57 at aa 17-38, sequence LSQDALAEKLFISRQAISKWEN
553482000030	1 transmembrane helix predicted for SEQ0004 by TMHMM2.0 at aa 99-117
553482000031	GTP-binding protein YchF; Reviewed; Region: PRK09601
553482000032	YchF GTPase; Region: YchF; cd01900
553482000033	G1 box; other site
553482000034	GTP/Mg2+ binding site [chemical binding]; other site
553482000035	Switch I region; other site
553482000036	G2 box; other site
553482000037	Switch II region; other site
553482000038	G3 box; other site
553482000039	G4 box; other site
553482000040	G5 box; other site
553482000041	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
553482000042	HMMPfam hit to PF01926, GTPase of unknown function, score 7.1e-35
553482000043	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000044	HMMPfam hit to PF06071, Protein of unknown function (DUF933), score 2.9e-61
553482000045	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
553482000046	putative active site [active]
553482000047	catalytic residue [active]
553482000048	HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 4.3e-81
553482000049	PS01196 Peptidyl-tRNA hydrolase signature 2.
553482000050	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
553482000051	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
553482000052	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482000053	ATP binding site [chemical binding]; other site
553482000054	putative Mg++ binding site [ion binding]; other site
553482000055	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482000056	nucleotide binding region [chemical binding]; other site
553482000057	ATP-binding site [chemical binding]; other site
553482000058	TRCF domain; Region: TRCF; cl04088
553482000059	HMMPfam hit to PF02559, CarD-like/TRCF domain, score 1e-50
553482000060	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 4.4e-06
553482000061	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.1e-40
553482000062	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000063	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8.4e-19
553482000064	HMMPfam hit to PF03461, TRCF domain, score 6.1e-35
553482000065	MatE; Region: MatE; cl10513
553482000066	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1e-05
553482000067	14 transmembrane helices predicted for SEQ0008 by TMHMM2.0 at aa 17-37, 52-74, 81-103, 118-140, 159-181, 185-202, 223-245, 281-303, 315-337, 347-369, 382-404, 409-426, 433-455 and 460-482
553482000068	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000069	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
553482000070	HMMPfam hit to PF01479, S4 domain, score 2.3e-10
553482000071	Septum formation initiator; Region: DivIC; cl11433
553482000072	1 transmembrane helix predicted for SEQ0010 by TMHMM2.0 at aa 37-54
553482000073	HMMPfam hit to PF04977, Septum formation initiator, score 2.2e-21
553482000074	Beta-lactamase class A [Defense mechanisms]; Region: PenP; COG2367
553482000075	SH3-like domain; Region: SH3_8; pfam13457
553482000076	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482000077	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000078	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
553482000079	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
553482000080	Ligand Binding Site [chemical binding]; other site
553482000081	B3/4 domain; Region: B3_4; cl11458
553482000082	HMMPfam hit to PF01171, PP-loop family, score 7e-85
553482000083	1 transmembrane helix predicted for SEQ0013 by TMHMM2.0 at aa 21-43
553482000084	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000085	active site
553482000086	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.2e-33
553482000087	FtsH Extracellular; Region: FtsH_ext; pfam06480
553482000088	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
553482000089	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000090	Walker A motif; other site
553482000091	ATP binding site [chemical binding]; other site
553482000092	Walker B motif; other site
553482000093	arginine finger; other site
553482000094	Peptidase family M41; Region: Peptidase_M41; pfam01434
553482000095	2 transmembrane helices predicted for SEQ0015 by TMHMM2.0 at aa 13-31 and 134-156
553482000096	HMMPfam hit to PF06480, FtsH Extracellular, score 1.1e-35
553482000097	HMMPfam hit to PF00004, ATPase family associated with various c, score 1.4e-91
553482000098	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000099	PS00674 AAA-protein family signature.
553482000100	HMMPfam hit to PF01434, Peptidase family M41, score 2e-108
553482000101	amino acid transporter; Region: 2A0306; TIGR00909
553482000102	Spore germination protein; Region: Spore_permease; cl15802
553482000103	Spore germination protein; Region: Spore_permease; cl15802
553482000104	HMMPfam hit to PF00324, Amino acid permease, score 1.3e-25
553482000105	12 transmembrane helices predicted for SEQ0016 by TMHMM2.0 at aa 48-70, 74-96, 108-130, 171-193, 200-222, 237-259, 280-302, 331-353, 374-396, 401-418, 431-453 and 457-479
553482000106	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000107	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000108	rod shape-determining protein MreC; Region: MreC; pfam04085
553482000109	1 transmembrane helix predicted for SEQ0017 by TMHMM2.0 at aa 9-31
553482000110	HMMPfam hit to PF04085, rod shape-determining protein MreC, score 2.2e-23
553482000111	6 transmembrane helices predicted for SEQ0018 by TMHMM2.0 at aa 7-29, 33-52, 57-74, 78-100, 107-126 and 136-158
553482000112	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
553482000113	NlpC/P60 family; Region: NLPC_P60; cl11438
553482000114	HMMPfam hit to PF05257, CHAP domain, score 2.7e-38
553482000115	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02269
553482000116	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
553482000117	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000118	active site
553482000119	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482000120	PS00114 Phosphoribosyl pyrophosphate synthetase signature.
553482000121	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 7.8e-35
553482000122	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482000123	Recombination protein O N terminal; Region: RecO_N; cl15812
553482000124	DNA repair protein RecO; Region: reco; TIGR00613
553482000125	Recombination protein O C terminal; Region: RecO_C; pfam02565
553482000126	HMMPfam hit to PF02565, Recombination protein O, score 2.4e-15
553482000127	PS00190 Cytochrome c family heme-binding site signature.
553482000128	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl00390
553482000129	HMMPfam hit to PF02504, Fatty acid synthesis protein, score 7.8e-129
553482000130	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482000131	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-06
553482000132	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
553482000133	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
553482000134	ATP binding site [chemical binding]; other site
553482000135	active site
553482000136	substrate binding site [chemical binding]; other site
553482000137	HMMPfam hit to PF01259, SAICAR synthetase, score 3.2e-106
553482000138	PS01057 SAICAR synthetase signature 1.
553482000139	PS01058 SAICAR synthetase signature 2.
553482000140	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
553482000141	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
553482000142	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
553482000143	dimerization interface [polypeptide binding]; other site
553482000144	ATP binding site [chemical binding]; other site
553482000145	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
553482000146	dimerization interface [polypeptide binding]; other site
553482000147	ATP binding site [chemical binding]; other site
553482000148	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
553482000149	putative active site [active]
553482000150	catalytic triad [active]
553482000151	1 transmembrane helix predicted for SEQ0026 by TMHMM2.0 at aa 7-29
553482000152	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1e-31
553482000153	PS01159 WW/rsp5/WWP domain signature.
553482000154	amidophosphoribosyltransferase; Provisional; Region: PRK07272
553482000155	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
553482000156	active site
553482000157	tetramer interface [polypeptide binding]; other site
553482000158	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000159	active site
553482000160	PS00443 Glutamine amidotransferases class-II active site.
553482000161	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 4.1e-36
553482000162	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.4e-10
553482000163	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482000164	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
553482000165	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
553482000166	dimerization interface [polypeptide binding]; other site
553482000167	putative ATP binding site [chemical binding]; other site
553482000168	HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 1.2e-70
553482000169	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1.1e-43
553482000170	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
553482000171	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
553482000172	active site
553482000173	substrate binding site [chemical binding]; other site
553482000174	cosubstrate binding site; other site
553482000175	catalytic site [active]
553482000176	HMMPfam hit to PF00551, Formyl transferase, score 1.6e-55
553482000177	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
553482000178	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
553482000179	purine monophosphate binding site [chemical binding]; other site
553482000180	dimer interface [polypeptide binding]; other site
553482000181	putative catalytic residues [active]
553482000182	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
553482000183	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
553482000184	HMMPfam hit to PF02142, MGS-like domain, score 9.1e-52
553482000185	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 2.2e-143
553482000186	Surface antigen [General function prediction only]; Region: COG3942
553482000187	NlpC/P60 family; Region: NLPC_P60; cl11438
553482000188	Bacterial SH3 domain; Region: SH3_3; cl02551
553482000189	HMMPfam hit to PF08460, Bacterial SH3 domain, score 8.9e-21
553482000190	HMMPfam hit to PF05257, CHAP domain, score 7.9e-29
553482000191	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
553482000192	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
553482000193	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482000194	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
553482000195	HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N d, score 1.4e-41
553482000196	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP, score 1.7e-119
553482000197	HMMPfam hit to PF08442, ATP-grasp domain, score 0.0042
553482000198	HMMPfam hit to PF02655, ATP-grasp domain, score 0.0011
553482000199	PS00184 Phosphoribosylglycinamide synthetase signature.
553482000200	HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C d, score 1.9e-13
553482000201	AIR carboxylase; Region: AIRC; cl00310
553482000202	HMMPfam hit to PF00731, AIR carboxylase, score 7.4e-90
553482000203	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
553482000204	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482000205	HMMPfam hit to PF02222, ATP-grasp domain, score 7e-64
553482000206	HMMPfam hit to PF02655, ATP-grasp domain, score 0.00061
553482000207	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae hypothetical protein UniProt:Q3D9U7 (EMBL:AAJR01000013 (317 aa) fasta scores: E()=0.0018, 66.667% id in 30 aa. Downstream CDS, SEQ0036a is similar to an internal region of the same protein.
553482000208	gene remnant. Upstream CDS, SEQ0036 is similar to the N-terminus of the same protein. Similar to an internal region of Streptococcus agalactiae COH1 hypothetical protein UniProt:Q3D9U7 (EMBL:AAJR01000013 (317 aa) fasta scores: E()=6.7, 35.484% id in 31 aa
553482000209	adenylosuccinate lyase; Provisional; Region: PRK07492
553482000210	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
553482000211	tetramer interface [polypeptide binding]; other site
553482000212	active site
553482000213	HMMPfam hit to PF00206, Lyase, score 8.8e-92
553482000214	PS00163 Fumarate lyases signature.
553482000215	CDS contains a frameshift after codon 77. Similar to Streptococcus pyogenes serotype M3 transcriptional regulator UniProt:Q1JP26 (EMBL:CP000259 (303 aa) fasta scores: E()=1.4e-83, 74.257% id in 303 aa
553482000216	HMMPfam hit to PF01381, Helix-turn-helix, score 6.2e-07
553482000217	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
553482000218	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000219	Walker A motif; other site
553482000220	ATP binding site [chemical binding]; other site
553482000221	Walker B motif; other site
553482000222	arginine finger; other site
553482000223	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
553482000224	HMMPfam hit to PF05496, Holliday junction DNA helicase ruvB N-termin, score 2.4e-26
553482000225	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.3e-26
553482000226	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.0002
553482000227	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000228	HMMPfam hit to PF05491, Holliday junction DNA helicase ruvB C-termin, score 1.5e-52
553482000229	Low molecular weight phosphatase family; Region: LMWPc; cd00115
553482000230	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
553482000231	active site
553482000232	HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 3.7e-33
553482000233	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
553482000234	1 transmembrane helix predicted for SEQ0042 by TMHMM2.0 at aa 20-39
553482000235	HMMPfam hit to PF02493, MORN repeat, score 3.5e-05
553482000236	HMMPfam hit to PF02493, MORN repeat, score 0.001
553482000237	HMMPfam hit to PF02493, MORN repeat, score 0.00052
553482000238	OpgC protein; Region: OpgC_C; cl00792
553482000239	Acyltransferase family; Region: Acyl_transf_3; pfam01757
553482000240	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
553482000241	catalytic triad [active]
553482000242	catalytic triad [active]
553482000243	oxyanion hole [active]
553482000244	HMMPfam hit to PF01757, Acyltransferase family, score 7.1e-31
553482000245	11 transmembrane helices predicted for SEQ0043 by TMHMM2.0 at aa 5-23, 27-49, 69-90, 131-153, 166-188, 192-214, 235-257, 261-283, 295-317, 327-349 and 370-392
553482000246	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
553482000247	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
553482000248	putative catalytic cysteine [active]
553482000249	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
553482000250	putative active site [active]
553482000251	metal binding site [ion binding]; metal-binding site
553482000252	HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 3.4e-07
553482000253	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000254	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.3e-142
553482000255	PS00913 Iron-containing alcohol dehydrogenases signature 1.
553482000256	PS00060 Iron-containing alcohol dehydrogenases signature 2.
553482000257	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286
553482000258	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
553482000259	catalytic Zn binding site [ion binding]; other site
553482000260	structural Zn binding site [ion binding]; other site
553482000261	NAD(P) binding site [chemical binding]; other site
553482000262	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.4e-37
553482000263	PS00059 Zinc-containing alcohol dehydrogenases signature.
553482000264	HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.7e-36
553482000265	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
553482000266	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
553482000267	NAD binding site [chemical binding]; other site
553482000268	substrate binding site [chemical binding]; other site
553482000269	catalytic Zn binding site [ion binding]; other site
553482000270	tetramer interface [polypeptide binding]; other site
553482000271	structural Zn binding site [ion binding]; other site
553482000272	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 9.5e-49
553482000273	PS00190 Cytochrome c family heme-binding site signature.
553482000274	PS00059 Zinc-containing alcohol dehydrogenases signature.
553482000275	HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.2e-39
553482000276	genomic island
553482000277	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482000278	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482000279	The MRP (Mutidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export.  They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins.  The ABCC subfamily contains transporters with a...; Region: ABCC_MRP_Like; cd03228
553482000280	Walker A/P-loop; other site
553482000281	ATP binding site [chemical binding]; other site
553482000282	Q-loop/lid; other site
553482000283	ABC transporter signature motif; other site
553482000284	Walker B; other site
553482000285	D-loop; other site
553482000286	H-loop/switch region; other site
553482000287	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.1e-05
553482000288	5 transmembrane helices predicted for SEQ0047 by TMHMM2.0 at aa 12-34, 49-71, 124-146, 150-169 and 235-257
553482000289	HMMPfam hit to PF00005, ABC transporter, score 4.6e-27
553482000290	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000291	CDS contains a frameshift after codon 214. Similar to Enterococcus faecalis (Streptococcus faecalis) HesA/MoeB/ThiF family protein UniProt:Q835P7 (EMBL:AE016830 (377 aa) fasta scores: E()=8.8e-21, 28.609% id in 381 aa
553482000292	HMMPfam hit to PF00899, ThiF family, score 1.3e-08
553482000293	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482000294	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482000295	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 0.00016
553482000296	PS00143 Insulinase family, zinc-binding region signature.
553482000297	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 0.00018
553482000298	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000299	non-specific DNA binding site [nucleotide binding]; other site
553482000300	salt bridge; other site
553482000301	sequence-specific DNA binding site [nucleotide binding]; other site
553482000302	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482000303	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-05
553482000304	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
553482000305	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants, cyanobacteria; Region: Thr-synth_2; cd01560
553482000306	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482000307	catalytic residue [active]
553482000308	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.8e-08
553482000309	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
553482000310	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
553482000311	MatE; Region: MatE; cl10513
553482000312	MatE; Region: MatE; cl10513
553482000313	HMMPfam hit to PF01554, MatE, score 9e-21
553482000314	9 transmembrane helices predicted for SEQ0053 by TMHMM2.0 at aa 27-49, 53-75, 87-109, 129-151, 163-182, 186-208, 306-328, 343-365 and 387-409
553482000315	HMMPfam hit to PF01554, MatE, score 1.3e-27
553482000316	Ribosomal protein S10p/S20e; Region: Ribosomal_S10; cl00314
553482000317	HMMPfam hit to PF00338, Ribosomal protein S10p/S20e, score 7.5e-60
553482000318	PS00361 Ribosomal protein S10 signature.
553482000319	Ribosomal protein L3; Region: Ribosomal_L3; cl00324
553482000320	HMMPfam hit to PF00297, Ribosomal protein L3, score 1.7e-92
553482000321	PS00474 Ribosomal protein L3 signature.
553482000322	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
553482000323	HMMPfam hit to PF00573, Ribosomal protein L4/L1 family, score 2.4e-72
553482000324	Ribosomal protein L23; Region: Ribosomal_L23; cl00326
553482000325	HMMPfam hit to PF00276, Ribosomal protein L23, score 3.1e-32
553482000326	PS00050 Ribosomal protein L23 signature.
553482000327	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
553482000328	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
553482000329	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
553482000330	HMMPfam hit to PF00181, Ribosomal Proteins L2, RNA binding dom, score 8e-48
553482000331	HMMPfam hit to PF03947, Ribosomal Proteins L2, C-terminal doma, score 8.8e-87
553482000332	PS00467 Ribosomal protein L2 signature.
553482000333	Ribosomal protein S19; Region: Ribosomal_S19; cl00350
553482000334	HMMPfam hit to PF00203, Ribosomal protein S19, score 3.1e-51
553482000335	PS00323 Ribosomal protein S19 signature.
553482000336	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
553482000337	putative translocon binding site; other site
553482000338	protein-rRNA interface [nucleotide binding]; other site
553482000339	HMMPfam hit to PF00237, Ribosomal protein L22p/L17e, score 2.3e-60
553482000340	PS00464 Ribosomal protein L22 signature.
553482000341	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
553482000342	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
553482000343	G-X-X-G motif; other site
553482000344	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
553482000345	HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal domai, score 4.9e-29
553482000346	HMMPfam hit to PF07650, KH domain, score 4.8e-23
553482000347	HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal domai, score 1.4e-50
553482000348	PS00548 Ribosomal protein S3 signature.
553482000349	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
553482000350	23S rRNA interface [nucleotide binding]; other site
553482000351	5S rRNA interface [nucleotide binding]; other site
553482000352	putative antibiotic binding site [chemical binding]; other site
553482000353	L25 interface [polypeptide binding]; other site
553482000354	L27 interface [polypeptide binding]; other site
553482000355	HMMPfam hit to PF00252, Ribosomal protein L16, score 1.2e-82
553482000356	PS00586 Ribosomal protein L16 signature 1.
553482000357	PS00701 Ribosomal protein L16 signature 2.
553482000358	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
553482000359	23S rRNA interface [nucleotide binding]; other site
553482000360	putative translocon interaction site; other site
553482000361	signal recognition particle (SRP54) interaction site; other site
553482000362	L23 interface [polypeptide binding]; other site
553482000363	trigger factor interaction site; other site
553482000364	HMMPfam hit to PF00831, Ribosomal L29 protein, score 2.1e-28
553482000365	Ribosomal protein S17; Region: Ribosomal_S17; cl00351
553482000366	HMMPfam hit to PF00366, Ribosomal protein S17, score 1.6e-36
553482000367	PS00056 Ribosomal protein S17 signature.
553482000368	Ribosomal protein L14p/L23e; Region: Ribosomal_L14; cl00328
553482000369	PS00049 Ribosomal protein L14 signature.
553482000370	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
553482000371	KOW motif; Region: KOW; cl00354
553482000372	HMMPfam hit to PF00467, KOW motif, score 6.6e-09
553482000373	PS01108 Ribosomal protein L24 signature.
553482000374	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
553482000375	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
553482000376	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
553482000377	HMMPfam hit to PF00281, Ribosomal protein L5, score 7.2e-30
553482000378	PS00358 Ribosomal protein L5 signature.
553482000379	HMMPfam hit to PF00673, ribosomal L5P family C-terminus, score 5.9e-53
553482000380	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
553482000381	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 9.7e-20
553482000382	PS00527 Ribosomal protein S14 signature.
553482000383	Ribosomal protein S8; Region: Ribosomal_S8; cl00330
553482000384	HMMPfam hit to PF00410, Ribosomal protein S8, score 4.8e-76
553482000385	PS00053 Ribosomal protein S8 signature.
553482000386	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
553482000387	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
553482000388	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
553482000389	HMMPfam hit to PF00347, Ribosomal protein L6, score 1.5e-24
553482000390	HMMPfam hit to PF00347, Ribosomal protein L6, score 2.2e-30
553482000391	PS00525 Ribosomal protein L6 signature 1.
553482000392	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
553482000393	5S rRNA interface [nucleotide binding]; other site
553482000394	L27 interface [polypeptide binding]; other site
553482000395	23S rRNA interface [nucleotide binding]; other site
553482000396	L5 interface [polypeptide binding]; other site
553482000397	HMMPfam hit to PF00861, Ribosomal L18p/L5e family, score 7.2e-56
553482000398	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
553482000399	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
553482000400	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
553482000401	HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal domai, score 1.3e-42
553482000402	PS00585 Ribosomal protein S5 signature.
553482000403	PS00589 PTS HPR component serine phosphorylation site signature.
553482000404	HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal domai, score 6.2e-35
553482000405	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
553482000406	23S rRNA binding site [nucleotide binding]; other site
553482000407	HMMPfam hit to PF00327, Ribosomal protein L30p/L7e, score 2.8e-14
553482000408	PS00634 Ribosomal protein L30 signature.
553482000409	Ribosomal protein L18e/L15; Region: Ribosomal_L18e; cl12022
553482000410	HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal re, score 5.3e-59
553482000411	HMMPfam hit to PF00256, Ribosomal protein L15, score 3.1e-11
553482000412	PS00475 Ribosomal protein L15 signature.
553482000413	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
553482000414	SecY translocase; Region: SecY; pfam00344
553482000415	10 transmembrane helices predicted for SEQ0075 by TMHMM2.0 at aa 20-42, 66-88, 117-139, 149-168, 175-197, 212-234, 267-289, 304-326, 368-390 and 395-414
553482000416	HMMPfam hit to PF00344, eubacterial secY protein, score 5.7e-167
553482000417	PS00755 Protein secY signature 1.
553482000418	PS00756 Protein secY signature 2.
553482000419	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482000420	adenylate kinase; Reviewed; Region: adk; PRK00279
553482000421	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
553482000422	AMP-binding site [chemical binding]; other site
553482000423	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
553482000424	HMMPfam hit to PF00406, Adenylate kinase, score 2e-86
553482000425	PS00113 Adenylate kinase signature.
553482000426	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
553482000427	rRNA binding site [nucleotide binding]; other site
553482000428	predicted 30S ribosome binding site; other site
553482000429	HMMPfam hit to PF00575, S1 RNA binding domain, score 3.2e-13
553482000430	HMMPfam hit to PF01176, Translation initiation factor 1A / IF-1, score 1.5e-35
553482000431	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
553482000432	PS00828 Ribosomal protein L36 signature.
553482000433	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
553482000434	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
553482000435	HMMPfam hit to PF00416, Ribosomal protein S13/S18, score 5.3e-55
553482000436	PS00646 Ribosomal protein S13 signature.
553482000437	Ribosomal protein S11; Region: Ribosomal_S11; cl00332
553482000438	HMMPfam hit to PF00411, Ribosomal protein S11, score 2.1e-72
553482000439	PS00054 Ribosomal protein S11 signature.
553482000440	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
553482000441	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
553482000442	alphaNTD homodimer interface [polypeptide binding]; other site
553482000443	alphaNTD - beta interaction site [polypeptide binding]; other site
553482000444	alphaNTD - beta' interaction site [polypeptide binding]; other site
553482000445	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; cl11613
553482000446	HMMPfam hit to PF01193, RNA polymerase Rpb3/Rpb11 dimerisation, score 6e-26
553482000447	HMMPfam hit to PF01000, RNA polymerase Rpb3/RpoA insert domain, score 1.5e-55
553482000448	HMMPfam hit to PF03118, Bacterial RNA polymerase, alpha chain C, score 1.3e-31
553482000449	Ribosomal protein L17; Region: Ribosomal_L17; cl00356
553482000450	HMMPfam hit to PF01196, Ribosomal protein L17, score 1.7e-62
553482000451	PS01167 Ribosomal protein L17 signature.
553482000452	Similar to the C-terminal region of Streptococcus mutans transposase UniProt:Q8DTK6 (EMBL:AE014133 (46 aa) blastp scores: E()=5e-04
553482000453	CDS contains a nonsense mutation (amber) after codon 115
553482000454	2 transmembrane helices predicted for SEQ0085 by TMHMM2.0 at aa 43-62 and 90-112
553482000455	1 transmembrane helix predicted for SEQ0086 by TMHMM2.0 at aa 73-95
553482000456	Domain of unknown function (DUF4176); Region: DUF4176; cl01867
553482000457	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482000458	10 transmembrane helices predicted for SEQ0089 by TMHMM2.0 at aa 13-35, 40-62, 75-94, 99-121, 161-183, 216-237, 250-272, 282-299, 306-323 and 343-365
553482000459	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000460	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000461	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482000462	2 transmembrane helices predicted for SEQ0090 by TMHMM2.0 at aa 13-32 and 375-392
553482000463	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.9e-13
553482000464	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-14
553482000465	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-16
553482000466	HMMPfam hit to PF00746, Gram positive anchor, score 1.3e-07
553482000467	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482000468	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
553482000469	nudix motif; other site
553482000470	HMMPfam hit to PF00293, NUDIX domain, score 4.3e-22
553482000471	PS00893 mutT domain signature.
553482000472	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
553482000473	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482000474	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
553482000475	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.3e-18
553482000476	HMMPfam hit to PF08544, GHMP kinases C terminal, score 3e-09
553482000477	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482000478	Helix-turn-helix domains; Region: HTH; cl00088
553482000479	HMMPfam hit to PF01047, MarR family, score 6.7e-14
553482000480	HMMPfam hit to PF08279, HTH domain, score 0.0028
553482000481	Predicted helix-turn-helix motif with score 2017.000, SD 6.06 at aa 52-73, sequence LTNTDLAKRLNISQAAVTKAIK
553482000482	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
553482000483	ABC component of the metal-type transporters.  This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc.  The ATPases of this group of transporters are very similar to members of...; Region: ABC_Metallic_Cations; cd03235
553482000484	HMMPfam hit to PF00005, ABC transporter, score 2.6e-47
553482000485	PS00211 ABC transporters family signature.
553482000486	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482000487	ABC-ATPase subunit  interface; other site
553482000488	dimer interface [polypeptide binding]; other site
553482000489	putative PBP binding regions; other site
553482000490	HMMPfam hit to PF00950, ABC 3 transport family, score 1.7e-90
553482000491	7 transmembrane helices predicted for SEQ0095 by TMHMM2.0 at aa 10-32, 53-75, 85-107, 134-156, 176-198, 219-241 and 245-267
553482000492	HMMPfam hit to PF01032, FecCD transport family, score 0.004
553482000493	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
553482000494	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
553482000495	active site
553482000496	HIGH motif; other site
553482000497	dimer interface [polypeptide binding]; other site
553482000498	KMSKS motif; other site
553482000499	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
553482000500	HMMPfam hit to PF01479, S4 domain, score 1.2e-06
553482000501	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 2.6e-116
553482000502	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482000503	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
553482000504	Transglycosylase; Region: Transgly; cl07896
553482000505	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482000506	1 transmembrane helix predicted for SEQ0097 by TMHMM2.0 at aa 38-60
553482000507	HMMPfam hit to PF00912, Transglycosylase, score 1.6e-76
553482000508	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482000509	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 7.9e-15
553482000510	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000511	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
553482000512	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl04593
553482000513	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
553482000514	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
553482000515	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl04593
553482000516	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
553482000517	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
553482000518	RPB1 interaction site [polypeptide binding]; other site
553482000519	RPB10 interaction site [polypeptide binding]; other site
553482000520	RPB11 interaction site [polypeptide binding]; other site
553482000521	RPB3 interaction site [polypeptide binding]; other site
553482000522	RPB12 interaction site [polypeptide binding]; other site
553482000523	HMMPfam hit to PF04563, RNA polymerase beta subunit, score 3e-55
553482000524	HMMPfam hit to PF04561, RNA polymerase Rpb2, domain, score 1.9e-08
553482000525	HMMPfam hit to PF04565, RNA polymerase Rpb2, domain, score 1.6e-39
553482000526	HMMPfam hit to PF00562, RNA polymerase Rpb2, domain, score 1.4e-211
553482000527	PS01166 RNA polymerases beta chain signature.
553482000528	HMMPfam hit to PF04560, RNA polymerase Rpb2, domain, score 1.1e-49
553482000529	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
553482000530	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
553482000531	RNA polymerase Rpb1, domain 2; Region: RNA_pol_Rpb1_2; cl11591
553482000532	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
553482000533	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
553482000534	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
553482000535	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
553482000536	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
553482000537	G-loop; other site
553482000538	DNA binding site [nucleotide binding]
553482000539	HMMPfam hit to PF04997, RNA polymerase Rpb1, domain, score 2.2e-142
553482000540	HMMPfam hit to PF00623, RNA polymerase Rpb1, domain, score 1.3e-83
553482000541	HMMPfam hit to PF04983, RNA polymerase Rpb1, domain, score 6.3e-71
553482000542	HMMPfam hit to PF05000, RNA polymerase Rpb1, domain, score 4.2e-23
553482000543	HMMPfam hit to PF04998, RNA polymerase Rpb1, domain, score 1.7e-78
553482000544	gene remnant. Similar to C-terminal region Streptococcus pneumoniae IS1167 transposase UniProt:Q97SC5 (EMBL:AE005672 (422 aa) fasta scores: E()=5e-12, 65.714% id in 70 aa
553482000545	Acyltransferase family; Region: Acyl_transf_3; pfam01757
553482000546	10 transmembrane helices predicted for SEQ0103 by TMHMM2.0 at aa 13-35, 50-67, 87-104, 119-141, 154-176, 196-215, 228-247, 252-271, 284-306 and 316-338
553482000547	Protein of unknown function (DUF1033); Region: DUF1033; cl11549
553482000548	HMMPfam hit to PF06279, Protein of unknown function (DUF1033), score 6.2e-68
553482000549	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4652
553482000550	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
553482000551	8 transmembrane helices predicted for SEQ0105 by TMHMM2.0 at aa 5-24, 153-175, 203-225, 229-260, 273-295, 563-585, 605-627 and 631-650
553482000552	HMMPfam hit to PF07242, Protein of unknown function (DUF1430), score 4.1e-37
553482000553	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482000554	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482000555	Walker A/P-loop; other site
553482000556	ATP binding site [chemical binding]; other site
553482000557	Q-loop/lid; other site
553482000558	ABC transporter signature motif; other site
553482000559	Walker B; other site
553482000560	D-loop; other site
553482000561	H-loop/switch region; other site
553482000562	HMMPfam hit to PF00005, ABC transporter, score 8.7e-53
553482000563	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000564	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000565	Type II/IV secretion system protein; Region: T2SE; pfam00437
553482000566	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482000567	Walker A motif; other site
553482000568	ATP binding site [chemical binding]; other site
553482000569	Walker B motif; other site
553482000570	HMMPfam hit to PF00437, Type II/IV secretion system protein, score 4e-30
553482000571	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000572	PS00662 Bacterial type II secretion system protein E signature.
553482000573	Type II secretion system (T2SS), protein F; Region: T2SF; cl00906
553482000574	Type II secretion system (T2SS), protein F; Region: T2SF; cl00906
553482000575	HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 5.1e-16
553482000576	3 transmembrane helices predicted for SEQ0108 by TMHMM2.0 at aa 124-146, 161-183 and 315-337
553482000577	HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 9.4e-20
553482000578	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
553482000579	HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 6.8e-06
553482000580	1 transmembrane helix predicted for SEQ0109 by TMHMM2.0 at aa 15-37
553482000581	1 transmembrane helix predicted for SEQ0110 by TMHMM2.0 at aa 7-29
553482000582	Type II secretory pathway pseudopilin; Region: PulG; pfam11773
553482000583	1 transmembrane helix predicted for SEQ0111 by TMHMM2.0 at aa 12-34
553482000584	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
553482000585	1 transmembrane helix predicted for SEQ0112 by TMHMM2.0 at aa 9-31
553482000586	PS00012 Phosphopantetheine attachment site.
553482000587	1 transmembrane helix predicted for SEQ0113 by TMHMM2.0 at aa 9-31
553482000588	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000589	Helix-turn-helix domains; Region: HTH; cl00088
553482000590	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482000591	HMMPfam hit to PF01527, Transposase, score 0.00062
553482000592	HMMPfam hit to PF02178, no description, score 0.21
553482000594	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
553482000595	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482000596	Acetokinase family; Region: Acetate_kinase; cl01029
553482000597	propionate/acetate kinase; Provisional; Region: PRK12379
553482000598	HMMPfam hit to PF00871, Acetokinase family, score 4.1e-196
553482000599	PS01076 Acetate and butyrate kinases family signature 2.
553482000600	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000601	Helix-turn-helix domains; Region: HTH; cl00088
553482000602	HMMPfam hit to PF01527, Transposase, score 0.00051
553482000603	putative transposase OrfB; Reviewed; Region: PHA02517
553482000604	HTH-like domain; Region: HTH_21; pfam13276
553482000605	Integrase core domain; Region: rve; cl01316
553482000606	Integrase core domain; Region: rve_3; cl15866
553482000607	HMMPfam hit to PF00665, Integrase core domain, score 7.5e-38
553482000608	3 transmembrane helices predicted for SEQ0121 by TMHMM2.0 at aa 7-29, 104-126 and 147-169
553482000609	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482000610	PRD domain; Region: PRD; cl15445
553482000611	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482000612	P-loop; other site
553482000613	active site
553482000614	phosphorylation site [posttranslational modification]
553482000615	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482000616	active site
553482000617	phosphorylation site [posttranslational modification]
553482000618	HMMPfam hit to PF00874, PRD domain, score 1.2e-14
553482000619	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 9.8e-27
553482000620	PS00372 PTS EIIA domains phosphorylation site signature 2.
553482000621	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
553482000622	P-loop; other site
553482000623	active site
553482000624	phosphorylation site [posttranslational modification]
553482000625	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1.4e-26
553482000626	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
553482000627	HMMPfam hit to PF04215, sugar-specific permease, SgaT/UlaA, score 2.6e-113
553482000628	11 transmembrane helices predicted for SEQ0124 by TMHMM2.0 at aa 4-26, 33-55, 86-108, 115-137, 141-163, 220-242, 257-279, 311-333, 337-359, 371-393 and 416-438
553482000629	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
553482000630	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000631	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
553482000632	TPP-binding site [chemical binding]; other site
553482000633	dimer interface [polypeptide binding]; other site
553482000634	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 1.2e-19
553482000635	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
553482000636	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
553482000637	PYR/PP interface [polypeptide binding]; other site
553482000638	dimer interface [polypeptide binding]; other site
553482000639	TPP binding site [chemical binding]; other site
553482000640	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482000641	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.4e-15
553482000642	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 2e-16
553482000643	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
553482000644	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
553482000645	active site
553482000646	Zn binding site [ion binding]; other site
553482000647	HMMPfam hit to PF05649, Peptidase family M13, score 1.2e-171
553482000648	HMMPfam hit to PF01431, Peptidase family M13, score 2.5e-73
553482000649	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482000650	elongation factor Ts; Provisional; Region: tsf; PRK09377
553482000651	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
553482000652	Elongation factor TS; Region: EF_TS; pfam00889
553482000653	HMMPfam hit to PF00889, Elongation factor TS, score 2.7e-54
553482000654	HMMPfam hit to PF00627, UBA/TS-N domain, score 5.5e-12
553482000655	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
553482000656	rRNA interaction site [nucleotide binding]; other site
553482000657	S8 interaction site; other site
553482000658	putative laminin-1 binding site; other site
553482000659	HMMPfam hit to PF00318, Ribosomal protein S2, score 1.5e-100
553482000660	PS00962 Ribosomal protein S2 signature 1.
553482000661	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
553482000662	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
553482000663	catalytic residue [active]
553482000664	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
553482000665	catalytic residues [active]
553482000666	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482000667	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482000668	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 5.9e-51
553482000669	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 1.7e-17
553482000670	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
553482000671	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.0026
553482000672	peroxiredoxin; Region: AhpC; TIGR03137
553482000673	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
553482000674	dimer interface [polypeptide binding]; other site
553482000675	decamer (pentamer of dimers) interface [polypeptide binding]; other site
553482000676	catalytic triad [active]
553482000677	peroxidatic and resolving cysteines [active]
553482000678	HMMPfam hit to PF00578, AhpC/TSA family, score 7.7e-90
553482000679	HMMPfam hit to PF08534, Redoxin, score 6e-14
553482000680	prophage phiSeq1
553482000681	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
553482000682	Int/Topo IB signature motif; other site
553482000683	HMMPfam hit to PF00589, Phage integrase family, score 4.5e-19
553482000684	PemK-like protein; Region: PemK; cl00995
553482000685	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482000686	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000687	non-specific DNA binding site [nucleotide binding]; other site
553482000688	salt bridge; other site
553482000689	sequence-specific DNA binding site [nucleotide binding]; other site
553482000690	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482000691	Catalytic site [active]
553482000692	HMMPfam hit to PF00717, Peptidase S24-like, score 4.8e-17
553482000693	HMMPfam hit to PF01381, Helix-turn-helix, score 1.7e-15
553482000694	Predicted helix-turn-helix motif with score 2380.000, SD 7.29 at aa 16-37, sequence VSVEELAKKLGVSKTTIYRYEK
553482000695	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482000696	non-specific DNA binding site [nucleotide binding]; other site
553482000697	salt bridge; other site
553482000698	sequence-specific DNA binding site [nucleotide binding]; other site
553482000699	Predicted helix-turn-helix motif with score 1591.000, SD 4.61 at aa 16-37, sequence TTQQAVADSIGIDRSTFYRKMK
553482000700	KTSC domain; Region: KTSC; pfam13619
553482000701	Predicted helix-turn-helix motif with score 1182.000, SD 3.21 at aa 38-59, sequence LNKKQISKMLGVDPKTFDVRFN
553482000702	Helix-turn-helix domains; Region: HTH; cl00088
553482000703	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
553482000704	RecT family; Region: RecT; cl04285
553482000705	HMMPfam hit to PF03837, RecT family, score 2.4e-66
553482000706	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
553482000707	CDS contains a frameshift after codon 18. Similar to Streptococcus pyogenes serotype M18 phage protein UniProt:Q8P088 (EMBL:AE010065 (137 aa) fasta scores: E()=5.3e-45, 96.350% id in 137 aa. Possible alternative translational start site after codon 24 which may generate a functional protein. Similar to Streptococcus pyogenes serotype M18 phage protein UniProt:Q8P1S1 (EMBL:AE010005 (113 aa) fasta scores: E()=3.6e-36, 98.230% id in 113 aa
553482000708	Protein of unknwon function (DUF3310); Region: DUF3310; pfam11753
553482000709	YopX protein; Region: YopX; cl09859
553482000710	1 transmembrane helix predicted for SEQ0157 by TMHMM2.0 at aa 26-45
553482000711	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482000712	HMMPfam hit to PF01555, DNA methylase, score 1.2e-05
553482000713	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000714	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000715	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482000716	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 2.4e-20
553482000717	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
553482000718	ParB-like nuclease domain; Region: ParBc; cl02129
553482000719	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
553482000720	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482000721	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.8e-11
553482000722	HMMPfam hit to PF01555, DNA methylase, score 7.9e-15
553482000723	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000724	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000725	Phage terminase large subunit; Region: Terminase_3; cl12054
553482000726	Terminase-like family; Region: Terminase_6; pfam03237
553482000727	HMMPfam hit to PF03237, Terminase-like family, score 1.6e-27
553482000728	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000729	phage portal protein, putative, A118 family; Region: A118_put_portal; TIGR01542
553482000730	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482000731	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
553482000732	HMMPfam hit to PF06152, Phage minor capsid protein, score 5.5e-213
553482000733	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482000734	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
553482000735	Minor capsid protein; Region: Minor_capsid_1; pfam10665
553482000736	Minor capsid protein; Region: Minor_capsid_2; pfam11114
553482000737	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
553482000738	PS00018 EF-hand calcium-binding domain.
553482000739	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
553482000740	HMMPfam hit to PF06854, Bacteriophage Gp15 protein, score 3.8e-126
553482000741	tape measure domain; Region: tape_meas_nterm; TIGR02675
553482000742	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
553482000743	linker region; other site
553482000744	4 transmembrane helices predicted for SEQ0180 by TMHMM2.0 at aa 305-327, 334-356, 397-419 and 432-454
553482000745	Phage-related protein [Function unknown]; Region: COG4722; cl15832
553482000746	Phage tail protein; Region: Sipho_tail; pfam05709
553482000747	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482000748	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482000749	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.4e-06
553482000750	gp58-like protein; Region: Gp58; pfam07902
553482000751	HMMPfam hit to PF07902, gp58-like protein, score 0
553482000752	PS00043 Bacterial regulatory proteins, gntR family signature.
553482000753	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482000754	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 2.9e-93
553482000755	Holin family; Region: Phage_holin_4; cl01989
553482000756	HMMPfam hit to PF05105, Holin family, score 4e-23
553482000757	3 transmembrane helices predicted for SEQ0188 by TMHMM2.0 at aa 16-38, 53-75 and 80-99
553482000758	1 transmembrane helix predicted for SEQ0189 by TMHMM2.0 at aa 7-29
553482000759	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482000760	NlpC/P60 family; Region: NLPC_P60; cl11438
553482000761	Bacterial SH3 domain; Region: SH3_3; cl02551
553482000762	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.7e-19
553482000763	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482000764	HMMPfam hit to PF05257, CHAP domain, score 5.1e-25
553482000765	HMMPfam hit to PF08460, Bacterial SH3 domain, score 3.5e-09
553482000766	Predicted helix-turn-helix motif with score 1031.000, SD 2.70 at aa 16-37, sequence ITTYKIGKKIGESTQFLDRYKN
553482000767	1 transmembrane helix predicted for SEQ0194 by TMHMM2.0 at aa 5-22
553482000768	Predicted helix-turn-helix motif with score 1139.000, SD 3.07 at aa 186-207, sequence TRIRDIALKFNIPETTLRGRYQ
553482000769	Predicted helix-turn-helix motif with score 1368.000, SD 3.85 at aa 83-104, sequence NKVSDLADKYGINQATLRNGIA
553482000770	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; Region: CSP_CDS; cd04458
553482000771	DNA-binding site [nucleotide binding]; DNA binding site
553482000772	RNA-binding motif; other site
553482000773	HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 1.5e-43
553482000774	PS00352 'Cold-shock' DNA-binding domain signature.
553482000775	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; cl01850
553482000776	PS00430 TonB-dependent receptor proteins signature 1.
553482000777	HMMPfam hit to PF05848, Firmicute transcriptional repressor of class, score 1e-99
553482000778	Predicted helix-turn-helix motif with score 1287.000, SD 3.57 at aa 26-47, sequence IKRSMLADSFQVVPSQINYVIK
553482000779	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
553482000780	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000781	Walker A motif; other site
553482000782	ATP binding site [chemical binding]; other site
553482000783	Walker B motif; other site
553482000784	arginine finger; other site
553482000785	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000786	Walker A motif; other site
553482000787	ATP binding site [chemical binding]; other site
553482000788	Walker B motif; other site
553482000789	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
553482000790	HMMPfam hit to PF02861, Clp amino terminal domain, score 0.036
553482000791	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000792	HMMPfam hit to PF02861, Clp amino terminal domain, score 0.27
553482000793	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.3e-07
553482000794	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000795	PS00870 Chaperonins clpA/B signature 1.
553482000796	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.4e-100
553482000797	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 6.3e-05
553482000798	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000799	PS00871 Chaperonins clpA/B signature 2.
553482000800	1 transmembrane helix predicted for SEQ0202 by TMHMM2.0 at aa 7-24
553482000801	1 transmembrane helix predicted for SEQ0203 by TMHMM2.0 at aa 7-24
553482000802	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is 'interfacial activation', the process of becoming...; Region: Lipase; cl14883
553482000803	nucleophilic elbow; other site
553482000804	catalytic triad; other site
553482000805	putative transposase OrfB; Reviewed; Region: PHA02517
553482000806	HTH-like domain; Region: HTH_21; pfam13276
553482000807	Integrase core domain; Region: rve; cl01316
553482000808	Integrase core domain; Region: rve_3; cl15866
553482000809	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482000810	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000811	Helix-turn-helix domains; Region: HTH; cl00088
553482000812	HMMPfam hit to PF01527, Transposase, score 0.00062
553482000813	HMMPfam hit to PF02178, no description, score 0.21
553482000814	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482000815	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
553482000816	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
553482000817	ring oligomerisation interface [polypeptide binding]; other site
553482000818	ATP/Mg binding site [chemical binding]; other site
553482000819	stacking interactions; other site
553482000820	hinge regions; other site
553482000821	HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 4.5e-195
553482000822	PS00296 Chaperonins cpn60 signature.
553482000823	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
553482000824	oligomerisation interface [polypeptide binding]; other site
553482000825	mobile loop; other site
553482000826	roof hairpin; other site
553482000827	HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 2e-32
553482000828	PS00681 Chaperonins cpn10 signature.
553482000829	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000830	Helix-turn-helix domains; Region: HTH; cl00088
553482000831	HMMPfam hit to PF01527, Transposase, score 0.00051
553482000832	putative transposase OrfB; Reviewed; Region: PHA02517
553482000833	HTH-like domain; Region: HTH_21; pfam13276
553482000834	Integrase core domain; Region: rve; cl01316
553482000835	Integrase core domain; Region: rve_3; cl15866
553482000836	HMMPfam hit to PF00665, Integrase core domain, score 2.2e-37
553482000837	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
553482000838	putative active site [active]
553482000839	nucleotide binding site [chemical binding]; other site
553482000840	nudix motif; other site
553482000841	putative metal binding site [ion binding]; other site
553482000842	HMMPfam hit to PF00293, NUDIX domain, score 1.1e-14
553482000843	PS00893 mutT domain signature.
553482000844	CDS contains a frameshift after codon 207. Similar to Streptococcus ratti MutR-like protein UniProt:Q3YB74 (EMBL:DQ145753 (292 aa) fasta scores: E()=7e-56, 56.842% id in 285 aa
553482000845	2 transmembrane helices predicted for SEQ0216 by TMHMM2.0 at aa 21-43 and 74-96
553482000846	9 transmembrane helices predicted for SEQ0217 by TMHMM2.0 at aa 13-35, 93-112, 119-141, 161-183, 204-226, 241-263, 297-319, 323-345 and 357-376
553482000847	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
553482000848	3 transmembrane helices predicted for SEQ0218 by TMHMM2.0 at aa 7-29, 56-78 and 138-155
553482000849	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482000850	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482000851	Walker A/P-loop; other site
553482000852	ATP binding site [chemical binding]; other site
553482000853	Q-loop/lid; other site
553482000854	ABC transporter signature motif; other site
553482000855	Walker B; other site
553482000856	D-loop; other site
553482000857	H-loop/switch region; other site
553482000858	HMMPfam hit to PF00005, ABC transporter, score 3.3e-08
553482000859	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000860	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000861	4 transmembrane helices predicted for SEQ0220 by TMHMM2.0 at aa 13-32, 47-69, 76-95 and 115-134
553482000862	4 transmembrane helices predicted for SEQ0221 by TMHMM2.0 at aa 5-27, 68-85, 92-114 and 129-151
553482000863	Predicted membrane protein [Function unknown]; Region: COG4640
553482000864	1 transmembrane helix predicted for SEQ0222 by TMHMM2.0 at aa 13-32
553482000865	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
553482000866	PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and...; Region: PseudoU_synth_RluCD_like; cd02869
553482000867	active site
553482000868	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.6e-47
553482000869	PS01129 Rlu family of pseudouridine synthase signature.
553482000870	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
553482000871	Transglutaminase-like superfamily; Region: Transglut_core; cl10469
553482000872	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
553482000873	homotrimer interaction site [polypeptide binding]; other site
553482000874	putative active site [active]
553482000875	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 0.0017
553482000876	Transglycosylase; Region: Transgly; cl07896
553482000877	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
553482000878	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482000879	1 transmembrane helix predicted for SEQ0227 by TMHMM2.0 at aa 100-122
553482000880	HMMPfam hit to PF00912, Transglycosylase, score 3e-80
553482000881	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000882	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.5e-44
553482000883	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000884	Ribosomal protein L33; Region: Ribosomal_L33; cl00383
553482000885	HMMPfam hit to PF00471, Ribosomal protein L33, score 5.1e-12
553482000886	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
553482000887	1 transmembrane helix predicted for SEQ0229 by TMHMM2.0 at aa 26-48
553482000888	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
553482000889	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
553482000890	putative homodimer interface [polypeptide binding]; other site
553482000891	KOW motif; Region: KOW; cl00354
553482000892	HMMPfam hit to PF02357, Transcription termination factor nusG, score 8e-52
553482000893	HMMPfam hit to PF00467, KOW motif, score 1.4e-07
553482000894	Helix-turn-helix domains; Region: HTH; cl00088
553482000895	Helix-turn-helix domains; Region: HTH; cl00088
553482000896	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482000897	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 3.7e-13
553482000898	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 3.3e-29
553482000899	Predicted helix-turn-helix motif with score 1528.000, SD 4.39 at aa 103-124, sequence ASLDDLAEALFISLSTLKRLIR
553482000900	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 4.9e-33
553482000901	gene remnant. CDS lacks an N-terminal signal sequence which is required for processing of this cell surface-anchored protein. Similar to the C-terminus of Streptococcus pyogenes serotype M18 Streptococcal protective antigen Spa UniProt:Q8NZA4 (EMBL:AE010108 (570 aa) fasta scores: E()=9.3e-13, 44.062% id in 320 aa
553482000902	HMMPfam hit to PF00746, Gram positive anchor, score 1.1e-08
553482000903	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482000904	1 transmembrane helix predicted for SEQ0232 by TMHMM2.0 at aa 251-273
553482000905	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
553482000906	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
553482000907	HIGH motif; other site
553482000908	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
553482000909	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482000910	active site
553482000911	KMSKS motif; other site
553482000912	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
553482000913	tRNA binding surface [nucleotide binding]; other site
553482000914	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 1.1e-12
553482000915	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482000916	HMMPfam hit to PF08264, Anticodon-binding domain, score 4.7e-07
553482000917	1 transmembrane helix predicted for SEQ0235 by TMHMM2.0 at aa 4-26
553482000918	CDS lacks appropriate translational start site and therefore does not have an intact N-terminal signal sequence. Similar to Streptococcus pneumoniae hypothetical protein SPR1549 UniProt:Q8CYF3 (EMBL:AE008523 (130 aa) fasta scores: E()=2.6e-11, 38.400% id in 125 aa
553482000919	6 transmembrane helices predicted for SEQ0237 by TMHMM2.0 at aa 7-26, 66-88, 109-131, 165-187, 194-216 and 236-253
553482000920	5 transmembrane helices predicted for SEQ0238 by TMHMM2.0 at aa 3-25, 60-82, 109-131, 141-163 and 176-198
553482000921	CDS contains a nonsense mutation (ochre) after codon 128. Similar to Streptococcus pneumoniae ABC transporter, ATP-binding protein UniProt:Q97PD4 (EMBL:AE005672 (210 aa) fasta scores: E()=1.8e-26, 52.913% id in 206 aa
553482000922	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000923	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
553482000924	HMMPfam hit to PF04215, sugar-specific permease, SgaT/UlaA, score 2.7e-250
553482000925	11 transmembrane helices predicted for SEQ0241 by TMHMM2.0 at aa 15-34, 41-63, 101-123, 132-154, 160-177, 237-257, 277-296, 339-361, 365-384, 397-419 and 434-456
553482000926	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
553482000927	P-loop; other site
553482000928	active site
553482000929	phosphorylation site [posttranslational modification]
553482000930	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1e-25
553482000931	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482000932	active site
553482000933	phosphorylation site [posttranslational modification]
553482000934	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 8.4e-34
553482000935	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
553482000936	active site
553482000937	dimer interface [polypeptide binding]; other site
553482000938	magnesium binding site [ion binding]; other site
553482000939	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 1.8e-55
553482000940	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
553482000941	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
553482000942	AP (apurinic/apyrimidinic) site pocket; other site
553482000943	DNA interaction; other site
553482000944	Metal-binding active site; metal-binding site
553482000945	HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 4e-45
553482000946	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
553482000947	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
553482000948	intersubunit interface [polypeptide binding]; other site
553482000949	active site
553482000950	Zn2+ binding site [ion binding]; other site
553482000951	HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 7.1e-96
553482000952	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000953	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482000954	PRD domain; Region: PRD; cl15445
553482000955	PRD domain; Region: PRD; cl15445
553482000956	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482000957	P-loop; other site
553482000958	active site
553482000959	phosphorylation site [posttranslational modification]
553482000960	HMMPfam hit to PF08279, HTH domain, score 0.001
553482000961	HMMPfam hit to PF00874, PRD domain, score 9.6e-15
553482000962	HMMPfam hit to PF00874, PRD domain, score 5.2e-16
553482000963	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482000964	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
553482000965	This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea.  This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily.  The characteristic feature of these...; Region: ABC_Pro_Gly_Bertaine; cd03294
553482000966	Walker A/P-loop; other site
553482000967	ATP binding site [chemical binding]; other site
553482000968	Q-loop/lid; other site
553482000969	ABC transporter signature motif; other site
553482000970	Walker B; other site
553482000971	D-loop; other site
553482000972	H-loop/switch region; other site
553482000973	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
553482000974	HMMPfam hit to PF00005, ABC transporter, score 4e-64
553482000975	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000976	PS00211 ABC transporters family signature.
553482000977	HMMPfam hit to PF00571, CBS domain pair, score 8.6e-13
553482000978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482000979	dimer interface [polypeptide binding]; other site
553482000980	conserved gate region; other site
553482000981	putative PBP binding loops; other site
553482000982	ABC-ATPase subunit interface; other site
553482000983	NMT1-like family; Region: NMT1_2; cl15260
553482000984	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
553482000985	7 transmembrane helices predicted for SEQ0251 by TMHMM2.0 at aa 48-67, 72-91, 98-120, 144-166, 215-237, 252-269 and 292-314
553482000986	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.4e-31
553482000987	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482000988	HMMPfam hit to PF04069, Substrate binding domain of ABC-type gly, score 3e-93
553482000989	DNA polymerase I; Provisional; Region: PRK05755
553482000990	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
553482000991	active site
553482000992	metal binding site 1 [ion binding]; metal-binding site
553482000993	putative 5' ssDNA interaction site; other site
553482000994	metal binding site 3; metal-binding site
553482000995	metal binding site 2 [ion binding]; metal-binding site
553482000996	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
553482000997	putative DNA binding site [nucleotide binding]; other site
553482000998	putative metal binding site [ion binding]; other site
553482000999	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
553482001000	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
553482001001	active site
553482001002	DNA binding site [nucleotide binding]
553482001003	catalytic site [active]
553482001004	HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 1.7e-93
553482001005	HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 5.8e-56
553482001006	HMMPfam hit to PF01612, 3'-5' exonuclease, score 0.011
553482001007	HMMPfam hit to PF00476, DNA polymerase family A, score 6.7e-212
553482001008	PS00447 DNA polymerase family A signature.
553482001009	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001010	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001011	HMMPfam hit to PF02629, CoA binding domain, score 1.1e-06
553482001012	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
553482001013	metal binding site 2 [ion binding]; metal-binding site
553482001014	putative DNA binding helix; other site
553482001015	metal binding site 1 [ion binding]; metal-binding site
553482001016	dimer interface [polypeptide binding]; other site
553482001017	structural Zn2+ binding site [ion binding]; other site
553482001018	HMMPfam hit to PF01475, Ferric uptake regulator family, score 6.8e-50
553482001019	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482001020	HMMPfam hit to PF00746, Gram positive anchor, score 1.8e-07
553482001021	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001022	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482001023	NPCBM/NEW2 domain; Region: NPCBM; cl07060
553482001024	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
553482001025	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.5e-05
553482001026	1 transmembrane helix predicted for SEQ0257 by TMHMM2.0 at aa 21-40
553482001027	HMMPfam hit to PF08305, NPCBM domain, score 1.2e-16
553482001028	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.63
553482001029	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2.3
553482001030	HMMPfam hit to PF00754, F5/8 type C domain, score 1.7e-12
553482001031	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001032	Protein of unknown function (DUF975); Region: DUF975; cl10504
553482001033	HMMPfam hit to PF06161, Protein of unknown function (DUF975), score 4e-79
553482001034	5 transmembrane helices predicted for SEQ0258 by TMHMM2.0 at aa 28-50, 60-82, 121-143, 153-175 and 220-242
553482001035	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
553482001036	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
553482001037	HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase, score 4.8e-145
553482001038	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482001039	1 transmembrane helix predicted for SEQ0260 by TMHMM2.0 at aa 13-35
553482001040	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.5e-12
553482001041	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.4e-12
553482001042	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.4e-12
553482001043	HMMPfam hit to PF00746, Gram positive anchor, score 1.5e-11
553482001044	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001045	putative transposase OrfB; Reviewed; Region: PHA02517
553482001046	HTH-like domain; Region: HTH_21; pfam13276
553482001047	Integrase core domain; Region: rve; cl01316
553482001048	Integrase core domain; Region: rve_3; cl15866
553482001049	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482001050	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001051	Helix-turn-helix domains; Region: HTH; cl00088
553482001052	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001053	HMMPfam hit to PF02178, no description, score 0.21
553482001054	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001055	Zinc finger domain containing protein (CHY type) [Function unknown]; Region: COG4357
553482001056	CHY zinc finger; Region: zf-CHY; pfam05495
553482001057	HMMPfam hit to PF05495, CHY zinc finger, score 4e-25
553482001058	PS00190 Cytochrome c family heme-binding site signature.
553482001059	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl01942
553482001060	5 transmembrane helices predicted for SEQ0264 by TMHMM2.0 at aa 15-37, 49-71, 86-108, 115-137 and 147-169
553482001061	HMMPfam hit to PF02632, BioY family, score 3e-18
553482001062	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482001063	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
553482001064	nucleoside/Zn binding site; other site
553482001065	dimer interface [polypeptide binding]; other site
553482001066	catalytic motif [active]
553482001067	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 6.7e-34
553482001068	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482001069	PS00041 Bacterial regulatory proteins, araC family signature.
553482001070	Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain [Cell division and chromosome partitioning]; Region: CYK3; COG5279
553482001071	Transglutaminase-like superfamily; Region: Transglut_core; cl10469
553482001072	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001073	1 transmembrane helix predicted for SEQ0268 by TMHMM2.0 at aa 13-35
553482001074	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
553482001075	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
553482001076	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
553482001077	DXD motif; other site
553482001078	5 transmembrane helices predicted for SEQ0269 by TMHMM2.0 at aa 7-29, 33-55, 319-341, 351-370 and 377-394
553482001079	HMMPfam hit to PF03142, Chitin synthase, score 0.0039
553482001080	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.1e-31
553482001081	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
553482001082	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001083	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
553482001084	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001085	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 5.5e-58
553482001086	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.0011
553482001087	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 1.6e-36
553482001088	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 6.6e-06
553482001089	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
553482001090	active site
553482001091	tetramer interface; other site
553482001092	HMMPfam hit to PF00483, Nucleotidyl transferase, score 3.2e-20
553482001093	gene remnant. Similar to the N-terminal region of Streptococcus pyogenes serotype M1 integral membrane protein (rhomboid family) UniProt:Q491A8 (EMBL:CP000017 (223 aa) fasta scores: E()=6.5e-33, 70.229% id in 131 aa
553482001094	HMMPfam hit to PF01694, Rhomboid family, score 2.6e-05
553482001095	3 transmembrane helices predicted for SEQ0273 by TMHMM2.0 at aa 12-34, 61-83 and 96-115
553482001096	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; cl00360
553482001097	HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 1.4e-43
553482001098	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001100	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001101	Helix-turn-helix domains; Region: HTH; cl00088
553482001102	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001103	HMMPfam hit to PF02178, no description, score 0.21
553482001104	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001105	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482001106	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482001107	1 transmembrane helix predicted for SEQ0280 by TMHMM2.0 at aa 48-70
553482001108	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1e-10
553482001109	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.1e-10
553482001110	HMMPfam hit to PF00746, Gram positive anchor, score 1.5e-08
553482001111	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001112	2 transmembrane helices predicted for SEQ0281 by TMHMM2.0 at aa 13-35 and 117-139
553482001113	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
553482001114	HMMPfam hit to PF03829, PTS system glucitol/sorbitol-specific IIA, score 3.2e-56
553482001115	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
553482001116	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
553482001117	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
553482001118	HMMPfam hit to PF07663, Sorbitol phosphotransferase enzyme II C-t, score 2e-51
553482001119	2 transmembrane helices predicted for SEQ0283 by TMHMM2.0 at aa 185-207 and 222-244
553482001120	HMMPfam hit to PF03612, Sorbitol phosphotransferase enzyme II N-t, score 7.5e-111
553482001121	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
553482001122	HMMPfam hit to PF03608, PTS system enzyme II sorbitol-specific facto, score 3.8e-135
553482001123	3 transmembrane helices predicted for SEQ0284 by TMHMM2.0 at aa 25-47, 68-90 and 141-160
553482001124	Glucitol operon activator protein (GutM); Region: GutM; cl01890
553482001125	HMMPfam hit to PF06923, Glucitol operon activator protein (GutM), score 1.4e-66
553482001126	1 transmembrane helix predicted for SEQ0285 by TMHMM2.0 at aa 4-23
553482001127	Helix-turn-helix domains; Region: HTH; cl00088
553482001128	PRD domain; Region: PRD; cl15445
553482001129	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482001130	P-loop; other site
553482001131	active site
553482001132	phosphorylation site [posttranslational modification]
553482001133	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482001134	active site
553482001135	phosphorylation site [posttranslational modification]
553482001136	HMMPfam hit to PF00874, PRD domain, score 7.3e-12
553482001137	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 0.0025
553482001138	HMMPfam hit to PF08279, HTH domain, score 1.1e-09
553482001139	Predicted helix-turn-helix motif with score 1780.000, SD 5.25 at aa 73-94, sequence LVIDDLADEIGVSRSTINKDLK
553482001140	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
553482001141	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
553482001142	active site
553482001143	dimer interface [polypeptide binding]; other site
553482001144	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
553482001145	dimer interface [polypeptide binding]; other site
553482001146	active site
553482001147	HMMPfam hit to PF00342, Phosphoglucose isomerase, score 1e-153
553482001148	PS00765 Phosphoglucose isomerase signature 1.
553482001149	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
553482001150	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
553482001151	Substrate binding site; other site
553482001152	Mg++ binding site; other site
553482001153	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
553482001154	active site
553482001155	substrate binding site [chemical binding]; other site
553482001156	CoA binding site [chemical binding]; other site
553482001157	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 14
553482001158	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.2
553482001159	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 36
553482001160	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 42
553482001161	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.99
553482001162	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 9.6
553482001163	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 4.2
553482001164	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.6e-10
553482001165	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
553482001166	active site
553482001167	tetramer interface; other site
553482001168	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.1e-18
553482001169	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
553482001170	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001171	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
553482001172	HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate deh, score 1.2e-70
553482001173	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 1.4e-80
553482001174	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 0.00046
553482001175	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482001176	Helix-turn-helix domains; Region: HTH; cl00088
553482001177	HMMPfam hit to PF01047, MarR family, score 2.4e-13
553482001178	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001179	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482001180	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482001181	Walker A/P-loop; other site
553482001182	ATP binding site [chemical binding]; other site
553482001183	Q-loop/lid; other site
553482001184	ABC transporter signature motif; other site
553482001185	Walker B; other site
553482001186	D-loop; other site
553482001187	H-loop/switch region; other site
553482001188	7 transmembrane helices predicted for SEQ0292 by TMHMM2.0 at aa 12-34, 52-74, 95-114, 124-146, 153-175, 235-257 and 264-286
553482001189	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.4e-21
553482001190	HMMPfam hit to PF00005, ABC transporter, score 4.9e-50
553482001191	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001192	PS00211 ABC transporters family signature.
553482001193	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001194	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482001195	MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins.  ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic...; Region: ABCC_MsbA; cd03251
553482001196	Walker A/P-loop; other site
553482001197	ATP binding site [chemical binding]; other site
553482001198	Q-loop/lid; other site
553482001199	ABC transporter signature motif; other site
553482001200	Walker B; other site
553482001201	D-loop; other site
553482001202	H-loop/switch region; other site
553482001203	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 6e-27
553482001204	5 transmembrane helices predicted for SEQ0293 by TMHMM2.0 at aa 16-33, 82-104, 154-173, 178-200 and 257-279
553482001205	PS00046 Histone H2A signature.
553482001206	HMMPfam hit to PF00005, ABC transporter, score 1.2e-55
553482001207	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001208	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
553482001209	HMMPfam hit to PF02677, Uncharacterized BCR, COG1636, score 1e-46
553482001210	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
553482001211	trimer interface [polypeptide binding]; other site
553482001212	active site
553482001213	HMMPfam hit to PF00692, dUTPase, score 1.7e-17
553482001214	DNA repair protein RadA; Provisional; Region: PRK11823
553482001215	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
553482001216	Walker A motif/ATP binding site; other site
553482001217	ATP binding site [chemical binding]; other site
553482001218	Walker B motif; other site
553482001219	Subunit ChlI of Mg-chelatase; Region: ChlI; cl12214
553482001220	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001221	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
553482001222	active site clefts [active]
553482001223	zinc binding site [ion binding]; other site
553482001224	dimer interface [polypeptide binding]; other site
553482001225	HMMPfam hit to PF00484, Carbonic anhydrase, score 1.2e-13
553482001226	Mitochondrial biogenesis AIM24; Region: AIM24; cl00884
553482001227	HMMPfam hit to PF01987, Protein of unknown function DUF124, score 3.8e-84
553482001228	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
553482001229	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
553482001230	active site
553482001231	HIGH motif; other site
553482001232	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
553482001233	active site
553482001234	KMSKS motif; other site
553482001235	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 4.3e-158
553482001236	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482001237	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482001238	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482001239	6 transmembrane helices predicted for SEQ0301 by TMHMM2.0 at aa 5-27, 45-67, 79-101, 116-138, 155-177 and 187-209
553482001240	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9.2e-07
553482001241	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482001242	6 transmembrane helices predicted for SEQ0302 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 111-133, 150-172 and 182-199
553482001243	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482001244	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482001245	active site
553482001246	phosphorylation site [posttranslational modification]
553482001247	intermolecular recognition site; other site
553482001248	dimerization interface [polypeptide binding]; other site
553482001249	LytTr DNA-binding domain; Region: LytTR; cl04498
553482001250	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.4e-07
553482001251	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 6.3e-26
553482001252	Ribonuclease P; Region: Ribonuclease_P; cl00457
553482001253	HMMPfam hit to PF00825, Ribonuclease P, score 4.8e-28
553482001254	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
553482001255	5 transmembrane helices predicted for SEQ0305 by TMHMM2.0 at aa 13-32, 52-74, 129-151, 171-193 and 206-228
553482001256	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001257	HMMPfam hit to PF02096, 60Kd inner membrane protein, score 4.4e-56
553482001258	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
553482001259	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
553482001260	G-X-X-G motif; other site
553482001261	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
553482001262	RxxxH motif; other site
553482001263	HMMPfam hit to PF01424, R3H domain, score 1.6e-11
553482001264	gene remnant. Similar to an internal region of Streptococcus thermophilus transposase Tnp1193 UniProt:Q5LYW0 (EMBL:CP000024 (448 aa) fasta scores: E()=1.9e-05, 45.333% id in 75 aa
553482001265	LXG domain of WXG superfamily; Region: LXG; pfam04740
553482001266	Possible gene remnant
553482001267	Nicotine adenine dinucleotide glycohydrolase (NADase); Region: NADase_NGA; pfam07461
553482001268	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001269	CDS contains a nonsense mutation (ochre) after codon 109
553482001270	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
553482001271	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
553482001272	putative active site cavity [active]
553482001273	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epi, score 5e-125
553482001274	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
553482001275	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482001276	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
553482001277	active site turn [active]
553482001278	phosphorylation site [posttranslational modification]
553482001279	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.2e-95
553482001280	10 transmembrane helices predicted for SEQ0316 by TMHMM2.0 at aa 12-34, 49-81, 88-110, 115-134, 155-177, 192-214, 263-285, 315-337, 344-366 and 371-393
553482001281	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 5.5e-14
553482001282	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482001283	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
553482001284	HPr interaction site; other site
553482001285	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482001286	active site
553482001287	phosphorylation site [posttranslational modification]
553482001288	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 3.1e-48
553482001289	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482001290	Helix-turn-helix domains; Region: HTH; cl00088
553482001291	Winged helix-turn helix; Region: HTH_29; pfam13551
553482001292	Helix-turn-helix domains; Region: HTH; cl00088
553482001293	Integrase core domain; Region: rve; cl01316
553482001294	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482001295	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001296	Ribosomal protein L34; Region: Ribosomal_L34; cl00370
553482001297	PS00784 Ribosomal protein L34 signature.
553482001298	CDS contains a nonsense mutation (amber) after codon 144. Similar to Streptococcus pyogenes serotype M3 N-acetylmannosamine-6-phosphate 2-epimerase NanE UniProt:Q8K8P4 (EMBL:AE014074 (234 aa) fasta scores: E()=9.5e-62, 76.923% id in 234 aa
553482001299	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epi, score 1.4e-118
553482001300	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
553482001301	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482001302	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.1e-27
553482001303	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001304	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001305	dimer interface [polypeptide binding]; other site
553482001306	conserved gate region; other site
553482001307	putative PBP binding loops; other site
553482001308	ABC-ATPase subunit interface; other site
553482001309	5 transmembrane helices predicted for SEQ0322 by TMHMM2.0 at aa 12-34, 70-92, 105-127, 158-180 and 264-286
553482001310	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-14
553482001311	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001312	dimer interface [polypeptide binding]; other site
553482001313	conserved gate region; other site
553482001314	putative PBP binding loops; other site
553482001315	ABC-ATPase subunit interface; other site
553482001316	PS00430 TonB-dependent receptor proteins signature 1.
553482001317	6 transmembrane helices predicted for SEQ0323 by TMHMM2.0 at aa 12-34, 76-98, 107-129, 134-156, 182-204 and 239-261
553482001318	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.3e-24
553482001319	Domain of unknown function (DUF386); Region: DUF386; cl01047
553482001320	HMMPfam hit to PF04074, Domain of unknown function (DUF386), score 2e-39
553482001321	Protein of unknown function, DUF624; Region: DUF624; cl02369
553482001322	5 transmembrane helices predicted for SEQ0325 by TMHMM2.0 at aa 26-48, 82-104, 117-139, 154-176 and 183-205
553482001323	HMMPfam hit to PF04854, Protein of unknown function, DUF624, score 1.6e-07
553482001324	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001325	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
553482001326	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
553482001327	catalytic residue [active]
553482001328	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 8e-35
553482001329	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001330	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482001331	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
553482001332	HMMPfam hit to PF00480, ROK family, score 8.8e-27
553482001333	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001334	gene remnant. Similar to the N-terminal region of Streptococcus suis acetyl xylan esterase UniProt:Q8RR40 (EMBL:AB071365 (323 aa) fasta scores: E()=8.5e-20, 55.319% id in 94 aa
553482001335	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
553482001336	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
553482001337	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
553482001338	putative active site [active]
553482001339	HMMPfam hit to PF01380, SIS domain, score 1.9e-11
553482001340	HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 0.0006
553482001341	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
553482001342	active site
553482001343	HMMPfam hit to PF01026, TatD related DNase, score 1.8e-122
553482001344	PS01137 Uncharacterized protein family UPF0006 signature 1.
553482001345	PS01091 Uncharacterized protein family UPF0006 signature 3.
553482001346	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
553482001347	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
553482001348	putative active site [active]
553482001349	putative metal binding site [ion binding]; other site
553482001350	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
553482001351	HMMPfam hit to PF01751, Toprim domain, score 2.7e-07
553482001352	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001353	HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase, score 7.8e-77
553482001354	PS01131 Ribosomal RNA adenine dimethylases signature.
553482001355	GTPase RsgA; Reviewed; Region: PRK00098
553482001356	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
553482001357	RNA binding site [nucleotide binding]; other site
553482001358	homodimer interface [polypeptide binding]; other site
553482001359	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
553482001360	GTPase/Zn-binding domain interface [polypeptide binding]; other site
553482001361	GTP/Mg2+ binding site [chemical binding]; other site
553482001362	G4 box; other site
553482001363	G1 box; other site
553482001364	Switch I region; other site
553482001365	G2 box; other site
553482001366	G3 box; other site
553482001367	Switch II region; other site
553482001368	HMMPfam hit to PF03193, Protein of unknown function, DUF258, score 9.8e-153
553482001369	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001370	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
553482001371	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
553482001372	substrate binding site [chemical binding]; other site
553482001373	hexamer interface [polypeptide binding]; other site
553482001374	metal binding site [ion binding]; metal-binding site
553482001375	HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase family, score 1.6e-107
553482001376	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase /, score 0.002
553482001377	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
553482001378	PS01086 Ribulose-phosphate 3-epimerase family signature 2.
553482001379	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
553482001380	Thiamine pyrophosphokinase; Region: TPK; cd07995
553482001381	active site
553482001382	dimerization interface [polypeptide binding]; other site
553482001383	thiamine binding site [chemical binding]; other site
553482001384	HMMPfam hit to PF04263, Thiamin pyrophosphokinase, catalytic d, score 5.7e-43
553482001385	HMMPfam hit to PF04265, Thiamin pyrophosphokinase, vitamin B1, score 1.7e-19
553482001386	hypothetical protein; Provisional; Region: PRK11281
553482001387	RmuC family; Region: RmuC; pfam02646
553482001388	1 transmembrane helix predicted for SEQ0336 by TMHMM2.0 at aa 3-22
553482001389	HMMPfam hit to PF02646, RmuC family, score 5.7e-138
553482001390	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
553482001391	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is inactive in...; Region: YhaM_OBF_like; cd04492
553482001392	generic binding surface II; other site
553482001393	generic binding surface I; other site
553482001394	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482001395	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 0.0052
553482001396	HMMPfam hit to PF01966, HD domain, score 4e-05
553482001397	pur operon repressor; Provisional; Region: PRK09213
553482001398	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
553482001399	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482001400	active site
553482001401	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 6.1e-17
553482001402	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
553482001403	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
553482001404	S17 interaction site [polypeptide binding]; other site
553482001405	S8 interaction site; other site
553482001406	16S rRNA interaction site [nucleotide binding]; other site
553482001407	streptomycin interaction site [chemical binding]; other site
553482001408	23S rRNA interaction site [nucleotide binding]; other site
553482001409	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
553482001410	HMMPfam hit to PF00164, Ribosomal protein S12, score 1e-64
553482001411	PS00055 Ribosomal protein S12 signature.
553482001412	Ribosomal protein S7p/S5e; Region: Ribosomal_S7; cl00313
553482001413	HMMPfam hit to PF00177, Ribosomal protein S7p/S5e, score 2e-81
553482001414	PS00052 Ribosomal protein S7 signature.
553482001415	elongation factor G; Reviewed; Region: PRK00007
553482001416	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
553482001417	G1 box; other site
553482001418	putative GEF interaction site [polypeptide binding]; other site
553482001419	GTP/Mg2+ binding site [chemical binding]; other site
553482001420	Switch I region; other site
553482001421	G2 box; other site
553482001422	G3 box; other site
553482001423	Switch II region; other site
553482001424	G4 box; other site
553482001425	G5 box; other site
553482001426	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
553482001427	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
553482001428	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
553482001429	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7.1e-113
553482001430	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001431	PS00301 GTP-binding elongation factors signature.
553482001432	HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.3e-18
553482001433	HMMPfam hit to PF03764, Elongation factor G, domain IV, score 5.7e-67
553482001434	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1e-46
553482001435	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001436	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
553482001437	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl15856
553482001438	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 1.5e-78
553482001439	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
553482001440	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 2.5e-99
553482001441	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482001442	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001443	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cl00198
553482001444	Phosphoglycerate kinase; Region: PGK; pfam00162
553482001445	substrate binding site [chemical binding]; other site
553482001446	hinge regions; other site
553482001447	ADP binding site [chemical binding]; other site
553482001448	catalytic site [active]
553482001449	HMMPfam hit to PF00162, Phosphoglycerate kinase, score 1.4e-179
553482001450	PS00111 Phosphoglycerate kinase signature.
553482001451	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
553482001452	4 transmembrane helices predicted for SEQ0349 by TMHMM2.0 at aa 21-43, 58-80, 87-109 and 114-136
553482001453	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
553482001454	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
553482001455	DNA binding residues [nucleotide binding]
553482001456	putative dimer interface [polypeptide binding]; other site
553482001457	HMMPfam hit to PF00376, MerR family regulatory protein, score 4.5e-10
553482001458	glutamine synthetase, type I; Region: GlnA; TIGR00653
553482001459	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
553482001460	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
553482001461	HMMPfam hit to PF03951, Glutamine synthetase, beta-Grasp domain, score 3e-14
553482001462	PS00180 Glutamine synthetase signature 1.
553482001463	HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 2.2e-152
553482001464	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
553482001465	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
553482001466	peptide binding site [polypeptide binding]; other site
553482001467	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001468	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2.8e-76
553482001469	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
553482001470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001471	dimer interface [polypeptide binding]; other site
553482001472	conserved gate region; other site
553482001473	putative PBP binding loops; other site
553482001474	ABC-ATPase subunit interface; other site
553482001475	6 transmembrane helices predicted for SEQ0353 by TMHMM2.0 at aa 9-31, 94-116, 128-150, 165-184, 225-247 and 275-297
553482001476	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.5e-49
553482001477	Predicted helix-turn-helix motif with score 1106.000, SD 2.95 at aa 200-221, sequence TDYIQLARAKGLTKRQVTRRHA
553482001478	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
553482001479	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
553482001480	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001481	dimer interface [polypeptide binding]; other site
553482001482	conserved gate region; other site
553482001483	putative PBP binding loops; other site
553482001484	ABC-ATPase subunit interface; other site
553482001485	5 transmembrane helices predicted for SEQ0354 by TMHMM2.0 at aa 42-64, 142-164, 191-213, 253-275 and 307-329
553482001486	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.6e-44
553482001487	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
553482001488	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482001489	Walker A/P-loop; other site
553482001490	ATP binding site [chemical binding]; other site
553482001491	Q-loop/lid; other site
553482001492	ABC transporter signature motif; other site
553482001493	Walker B; other site
553482001494	D-loop; other site
553482001495	H-loop/switch region; other site
553482001496	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482001497	HMMPfam hit to PF00005, ABC transporter, score 3.9e-56
553482001498	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001499	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 2.2e-27
553482001500	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
553482001501	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482001502	Walker A/P-loop; other site
553482001503	ATP binding site [chemical binding]; other site
553482001504	Q-loop/lid; other site
553482001505	ABC transporter signature motif; other site
553482001506	Walker B; other site
553482001507	D-loop; other site
553482001508	H-loop/switch region; other site
553482001509	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482001510	HMMPfam hit to PF00005, ABC transporter, score 2.2e-61
553482001511	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001512	PS00211 ABC transporters family signature.
553482001513	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 2.3e-08
553482001514	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
553482001515	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482001516	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
553482001517	HMMPfam hit to PF07521, RNA-metabolising metallo-beta-lactamase, score 1.4e-14
553482001518	PS01292 Uncharacterized protein family UPF0036 signature
553482001519	Protein of unknown function (DUF1447); Region: DUF1447; cl11492
553482001520	HMMPfam hit to PF07288, Protein of unknown function (DUF1447), score 5.9e-50
553482001521	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl14000
553482001522	HMMPfam hit to PF00814, Glycoprotease family, score 2.3e-54
553482001523	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
553482001524	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482001525	Coenzyme A binding pocket [chemical binding]; other site
553482001526	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.6e-15
553482001527	UGMP family protein; Validated; Region: PRK09604
553482001528	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl14000
553482001529	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
553482001530	HMMPfam hit to PF00814, Glycoprotease family, score 1.2e-76
553482001531	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
553482001532	putative active site [active]
553482001533	5 transmembrane helices predicted for SEQ0362 by TMHMM2.0 at aa 12-34, 49-71, 84-106, 126-148 and 304-326
553482001534	HMMPfam hit to PF02698, DUF218 domain, score 7.9e-48
553482001535	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
553482001536	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 2.1e-17
553482001537	HI0933-like protein; Region: HI0933_like; pfam03486
553482001538	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001539	HMMPfam hit to PF03486, HI0933-like protein, score 6e-207
553482001540	HMMPfam hit to PF00890, FAD binding domain, score 0.0042
553482001541	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 0.00028
553482001542	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00026
553482001543	Helix-turn-helix domains; Region: HTH; cl00088
553482001544	Predicted helix-turn-helix motif with score 1868.000, SD 5.55 at aa 22-43, sequence KTVSELADILGVSRQAVNNRVK
553482001545	HMMPfam hit to PF04394, Protein of unknown function, DUF536, score 5e-14
553482001546	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482001547	active site
553482001548	substrate binding site [chemical binding]; other site
553482001549	catalytic site [active]
553482001550	HMMPfam hit to PF00929, Exonuclease, score 3.2e-14
553482001551	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
553482001552	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
553482001553	DNA binding residues [nucleotide binding]
553482001554	dimer interface [polypeptide binding]; other site
553482001555	Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 5-26, sequence YSTGELAKAAGVTVRTVQYYDK
553482001556	HMMPfam hit to PF00376, MerR family regulatory protein, score 2.7e-12
553482001557	2 transmembrane helices predicted for SEQ0367 by TMHMM2.0 at aa 143-165 and 169-188
553482001558	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
553482001559	HMMPfam hit to PF02575, Uncharacterised BCR, YbaB family COG0718, score 1.9e-38
553482001560	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001561	1 transmembrane helix predicted for SEQ0369 by TMHMM2.0 at aa 21-43
553482001562	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-39
553482001563	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001564	Helix-turn-helix domains; Region: HTH; cl00088
553482001565	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001566	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001567	HMMPfam hit to PF02178, no description, score 0.21
553482001568	putative transposase OrfB; Reviewed; Region: PHA02517
553482001569	HTH-like domain; Region: HTH_21; pfam13276
553482001570	Integrase core domain; Region: rve; cl01316
553482001571	Integrase core domain; Region: rve_3; cl15866
553482001572	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482001573	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482001574	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
553482001575	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482001576	dimer interface [polypeptide binding]; other site
553482001577	phosphorylation site [posttranslational modification]
553482001578	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482001579	ATP binding site [chemical binding]; other site
553482001580	Mg2+ binding site [ion binding]; other site
553482001581	G-X-G motif; other site
553482001582	2 transmembrane helices predicted for SEQ0374 by TMHMM2.0 at aa 7-29 and 39-61
553482001583	HMMPfam hit to PF00672, HAMP domain, score 5.6e-08
553482001584	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-15
553482001585	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.4e-37
553482001586	1 transmembrane helix predicted for SEQ0375 by TMHMM2.0 at aa 242-261
553482001587	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1.8e-19
553482001588	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1.4e-19
553482001589	HMMPfam hit to PF02986, Fibronectin binding repeat, score 8.8e-18
553482001590	HMMPfam hit to PF02986, Fibronectin binding repeat, score 8.8e-18
553482001591	HMMPfam hit to PF02986, Fibronectin binding repeat, score 6.7e-18
553482001592	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 3.9e-27
553482001593	Helix-turn-helix domains; Region: HTH; cl00088
553482001594	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482001595	Helix-turn-helix domains; Region: HTH; cl00088
553482001596	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482001597	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 5e-06
553482001598	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 6.7e-16
553482001599	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 5.7e-32
553482001600	7 transmembrane helices predicted for SEQ0379 by TMHMM2.0 at aa 7-24, 34-56, 76-98, 113-132, 153-172, 177-194 and 201-223
553482001601	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 7.3e-19
553482001602	CDS contains a nonsense mutation (opal) after codon 40. Similar to Streptococcus pyogenes serotype M1 repressor-phage associated (transcriptional regulator) UniProt:Q99Y57 (EMBL:AE006612 (124 aa) fasta scores: E()=2.5e-32, 85.593% id in 118 aa
553482001603	HMMPfam hit to PF01381, Helix-turn-helix, score 3.2e-07
553482001604	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482001605	non-specific DNA binding site [nucleotide binding]; other site
553482001606	salt bridge; other site
553482001607	sequence-specific DNA binding site [nucleotide binding]; other site
553482001608	HMMPfam hit to PF01381, Helix-turn-helix, score 6.8e-11
553482001609	Predicted helix-turn-helix motif with score 1876.000, SD 5.58 at aa 22-43, sequence KTQKELSALTGISVRTLARYEK
553482001610	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
553482001611	HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 6.2e-20
553482001612	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
553482001613	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; cl07696
553482001614	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; cl08482
553482001615	HMMPfam hit to PF08530, X-Pro dipeptidyl-peptidase C-terminal n, score 6.6e-78
553482001616	HMMPfam hit to PF02129, X-Pro dipeptidyl-peptidase (S15 family), score 6.7e-151
553482001617	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
553482001618	Helix-turn-helix domains; Region: HTH; cl00088
553482001619	HMMPfam hit to PF00325, Bacterial regulatory proteins, crp family, score 0.00017
553482001620	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482001621	Major Facilitator Superfamily; Region: MFS_1; pfam07690
553482001622	putative substrate translocation pore; other site
553482001623	12 transmembrane helices predicted for SEQ0385 by TMHMM2.0 at aa 13-35, 45-64, 76-98, 108-127, 134-156, 166-188, 209-231, 241-263, 276-295, 300-322, 335-357 and 372-389
553482001624	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001625	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
553482001626	Ligand Binding Site [chemical binding]; other site
553482001627	HMMPfam hit to PF00582, Universal stress protein family, score 4.6e-21
553482001628	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
553482001629	amphipathic channel; other site
553482001630	Asn-Pro-Ala signature motifs; other site
553482001631	HMMPfam hit to PF00230, Major intrinsic protein, score 2.6e-14
553482001632	6 transmembrane helices predicted for SEQ0387 by TMHMM2.0 at aa 5-27, 42-64, 71-93, 143-165, 196-218 and 259-281
553482001633	PS00221 MIP family signature.
553482001634	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
553482001635	active site
553482001636	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482001637	HMMPfam hit to PF00144, Beta-lactamase, score 1.3e-52
553482001638	PS00146 Beta-lactamase class-A active site.
553482001639	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
553482001640	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
553482001641	HMMPfam hit to PF01228, Glycine radical, score 3.1e-41
553482001642	PS00850 Glycine radical signature.
553482001643	HMMPfam hit to PF02901, Pyruvate formate lyase, score 0
553482001644	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
553482001645	active site
553482001646	DNA polymerase IV; Validated; Region: PRK02406
553482001647	DNA binding site [nucleotide binding]
553482001648	HMMPfam hit to PF00817, impB/mucB/samB family, score 2.4e-103
553482001649	4 transmembrane helices predicted for SEQ0393 by TMHMM2.0 at aa 16-38, 69-91, 98-120 and 125-143
553482001650	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
553482001651	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
553482001652	DNA binding site [nucleotide binding]
553482001653	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482001654	Family description; Region: UvrD_C_2; cl15862
553482001655	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001656	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
553482001657	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
553482001658	Catalytic site [active]
553482001659	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
553482001660	HMMPfam hit to PF00717, Peptidase S24-like, score 1.3e-20
553482001661	PS00760 Signal peptidases I lysine active site.
553482001662	PS00501 Signal peptidases I serine active site.
553482001663	1 transmembrane helix predicted for SEQ0395 by TMHMM2.0 at aa 7-26
553482001664	ribonuclease HIII; Provisional; Region: PRK00996
553482001665	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
553482001666	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
553482001667	RNA/DNA hybrid binding site [nucleotide binding]; other site
553482001668	active site
553482001669	HMMPfam hit to PF01351, Ribonuclease HII, score 4.7e-62
553482001670	Colicin V production protein; Region: Colicin_V; cl00567
553482001671	HMMPfam hit to PF02674, Colicin V production protein, score 2.4e-44
553482001672	4 transmembrane helices predicted for SEQ0398 by TMHMM2.0 at aa 2-19, 23-40, 80-102 and 122-144
553482001673	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
553482001674	MutS2 homologs in bacteria and eukaryotes.  The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also...; Region: ABC_MutS2; cd03280
553482001675	Walker A/P-loop; other site
553482001676	ATP binding site [chemical binding]; other site
553482001677	Q-loop/lid; other site
553482001678	ABC transporter signature motif; other site
553482001679	Walker B; other site
553482001680	D-loop; other site
553482001681	H-loop/switch region; other site
553482001682	Smr domain; Region: Smr; cl02619
553482001683	HMMPfam hit to PF00488, MutS domain V, score 5.9e-15
553482001684	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001685	HMMPfam hit to PF01713, Smr domain, score 4.1e-35
553482001686	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001687	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
553482001688	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482001689	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482001690	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482001691	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 2.9e-27
553482001692	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3e-50
553482001693	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 0.00044
553482001694	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.5e-28
553482001695	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482001696	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001697	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
553482001698	catalytic residues [active]
553482001699	HMMPfam hit to PF00085, Thioredoxin, score 4.3e-32
553482001700	PS00194 Thioredoxin family active site.
553482001701	Mnd1 family; Region: Mnd1; pfam03962
553482001702	HMMPfam hit to PF00746, Gram positive anchor, score 0.00015
553482001703	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001704	1 transmembrane helix predicted for SEQ0402 by TMHMM2.0 at aa 13-35
553482001705	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
553482001706	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
553482001707	minor groove reading motif; other site
553482001708	helix-hairpin-helix signature motif; other site
553482001709	substrate binding pocket [chemical binding]; other site
553482001710	active site
553482001711	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
553482001712	DNA binding and oxoG recognition site [nucleotide binding]
553482001713	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 2e-06
553482001714	gene remnant. Similar to the C-terminal region of Streptococcus mutans hypothetical protein UniProt:Q8DTE7 (EMBL:AE014133 (125 aa) fasta scores: E()=2.9e-12, 72.340% id in 47 aa
553482001715	Ribosomal protein S6; Region: Ribosomal_S6; cl00414
553482001716	HMMPfam hit to PF01250, Ribosomal protein S6, score 2.7e-28
553482001717	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
553482001718	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482001719	dimer interface [polypeptide binding]; other site
553482001720	ssDNA binding site [nucleotide binding]; other site
553482001721	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482001722	HMMPfam hit to PF00436, Single-strand binding protein family, score 4.7e-32
553482001723	PS00583 pfkB family of carbohydrate kinases signature 1.
553482001724	Ribosomal protein S18; Region: Ribosomal_S18; cl00373
553482001725	HMMPfam hit to PF01084, Ribosomal protein S18, score 6.2e-34
553482001726	PS00057 Ribosomal protein S18 signature.
553482001727	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001728	Helix-turn-helix domains; Region: HTH; cl00088
553482001729	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001730	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001731	HMMPfam hit to PF02178, no description, score 0.21
553482001732	putative transposase OrfB; Reviewed; Region: PHA02517
553482001733	HTH-like domain; Region: HTH_21; pfam13276
553482001734	Integrase core domain; Region: rve; cl01316
553482001735	Integrase core domain; Region: rve_3; cl15866
553482001736	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482001737	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
553482001738	HMMPfam hit to PF06570, Protein of unknown function (DUF1129), score 2.5e-135
553482001739	4 transmembrane helices predicted for SEQ0414 by TMHMM2.0 at aa 84-106, 116-138, 151-173 and 183-202
553482001740	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
553482001741	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085; cl00459
553482001742	HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 2.6e-07
553482001743	2 transmembrane helices predicted for SEQ0415 by TMHMM2.0 at aa 255-277 and 287-309
553482001744	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
553482001745	The excision repair protein UvrA domain I; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_I; cd03270
553482001746	The excision repair protein UvrA domain I; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_I; cd03270
553482001747	The excision repair protein UvrA domain II; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_II; cd03271
553482001748	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001749	PS00190 Cytochrome c family heme-binding site signature.
553482001750	PS00211 ABC transporters family signature.
553482001751	HMMPfam hit to PF00005, ABC transporter, score 6.5e-33
553482001752	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001753	PS00190 Cytochrome c family heme-binding site signature.
553482001754	PS00211 ABC transporters family signature.
553482001755	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
553482001756	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
553482001757	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
553482001758	active site
553482001759	HMMPfam hit to PF00557, metallopeptidase family M24, score 3.4e-63
553482001760	PS00491 Aminopeptidase P and proline dipeptidase signature.
553482001761	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
553482001762	catalytic motif [active]
553482001763	Zn binding site [ion binding]; other site
553482001764	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 1.2e-31
553482001765	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482001766	Helix-turn-helix domains; Region: HTH; cl00088
553482001767	Winged helix-turn helix; Region: HTH_29; pfam13551
553482001768	Helix-turn-helix domains; Region: HTH; cl00088
553482001769	Integrase core domain; Region: rve; cl01316
553482001770	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482001771	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001772	elongation factor P; Validated; Region: PRK00529
553482001773	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
553482001774	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
553482001775	RNA binding site [nucleotide binding]; other site
553482001776	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
553482001777	RNA binding site [nucleotide binding]; other site
553482001778	HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 1.5e-18
553482001779	HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 4.3e-12
553482001780	PS01275 Elongation factor P signature.
553482001781	Asp23 family; Region: Asp23; cl00574
553482001782	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 7.5e-41
553482001783	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
553482001784	putative RNA binding site [nucleotide binding]; other site
553482001785	HMMPfam hit to PF01029, NusB family, score 1.3e-29
553482001786	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482001787	CDS contains a nonsense mutation (ochre) in comparison to SZO16200
553482001788	CDS contains a nonsense mutation (opal) in comparison to SZO16190
553482001789	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482001790	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482001791	DNA binding site [nucleotide binding]
553482001792	domain linker motif; other site
553482001793	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
553482001794	dimerization interface [polypeptide binding]; other site
553482001795	ligand binding site [chemical binding]; other site
553482001796	sodium binding site [ion binding]; other site
553482001797	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3.4e-05
553482001798	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001799	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.2e-10
553482001800	Predicted helix-turn-helix motif with score 1960.000, SD 5.86 at aa 3-24, sequence AKLTDVAALAGVSPTTVSRVIN
553482001801	PS00356 Bacterial regulatory proteins, lacI family signature.
553482001802	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
553482001803	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
553482001804	substrate binding [chemical binding]; other site
553482001805	active site
553482001806	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
553482001807	HMMPfam hit to PF08244, Glycosyl hydrolases family 32 C termi, score 2.2e-13
553482001808	HMMPfam hit to PF00251, Glycosyl hydrolases family 32 N termi, score 1.4e-127
553482001809	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
553482001810	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482001811	active site turn [active]
553482001812	phosphorylation site [posttranslational modification]
553482001813	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482001814	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
553482001815	HPr interaction site; other site
553482001816	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482001817	active site
553482001818	phosphorylation site [posttranslational modification]
553482001819	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 9.1e-19
553482001820	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482001821	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.1e-45
553482001822	10 transmembrane helices predicted for SEQ0431 by TMHMM2.0 at aa 111-132, 152-174, 181-203, 213-235, 254-276, 291-313, 334-354, 364-386, 391-413 and 433-455
553482001823	PS00044 Bacterial regulatory proteins, lysR family signature.
553482001824	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.4e-66
553482001825	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482001826	Endo-beta-N-acetylglucosaminidases are bacterial chitinases that hydrolyze the chitin core of various asparagine (N)-linked glycans and glycoproteins. The endo-beta-N-acetylglucosaminidases have a glycosyl hydrolase family 18 (GH18) catalytic domain; Region: GH18_EndoS-like; cd06542
553482001827	active site
553482001828	PS01095 Chitinases family 18 active site.
553482001829	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482001830	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
553482001831	HMMPfam hit to PF00480, ROK family, score 1.2e-69
553482001832	PS01125 ROK family signature.
553482001833	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
553482001834	Phosphomannose isomerase type I; Region: PMI_typeI; cl15429
553482001835	HMMPfam hit to PF01238, Phosphomannose isomerase type I, score 7.5e-98
553482001836	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
553482001837	SecA preprotein cross-linking domain; Region: SecA_PP_bind; cl03078
553482001838	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482001839	nucleotide binding region [chemical binding]; other site
553482001840	ATP-binding site [chemical binding]; other site
553482001841	SEC-C motif; Region: SEC-C; pfam02810
553482001842	HMMPfam hit to PF07517, SecA DEAD-like domain, score 1.7e-199
553482001843	HMMPfam hit to PF01043, SecA preprotein cross-linking domain, score 3.3e-61
553482001844	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.015
553482001845	PS01312 Protein secA signatures.
553482001846	HMMPfam hit to PF07516, SecA Wing and Scaffold domain, score 7.9e-68
553482001847	HMMPfam hit to PF02810, SEC-C motif, score 3.7e-07
553482001848	PS00200 Rieske iron-sulfur protein signature 2.
553482001849	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
553482001850	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1.2e-14
553482001851	alanine racemase; Reviewed; Region: alr; PRK00053
553482001852	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
553482001853	active site
553482001854	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
553482001855	dimer interface [polypeptide binding]; other site
553482001856	substrate binding site [chemical binding]; other site
553482001857	catalytic residues [active]
553482001858	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.2e-93
553482001859	PS00395 Alanine racemase pyridoxal-phosphate attachment site.
553482001860	HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 1e-66
553482001861	putative transposase OrfB; Reviewed; Region: PHA02517
553482001862	HTH-like domain; Region: HTH_21; pfam13276
553482001863	Integrase core domain; Region: rve; cl01316
553482001864	Integrase core domain; Region: rve_3; cl15866
553482001865	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482001866	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001867	Helix-turn-helix domains; Region: HTH; cl00088
553482001868	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001869	HMMPfam hit to PF02178, no description, score 0.21
553482001870	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001871	Surface antigen [General function prediction only]; Region: COG3942
553482001872	NlpC/P60 family; Region: NLPC_P60; cl11438
553482001873	HMMPfam hit to PF05257, CHAP domain, score 1.2e-45
553482001874	HMMPfam hit to PF07550, Protein of unknown function (DUF1533), score 0.00011
553482001875	HMMPfam hit to PF07550, Protein of unknown function (DUF1533), score 1.9e-13
553482001876	HMMPfam hit to PF05031, Iron Transport-associated domain, score 4.4e-06
553482001877	PS00018 EF-hand calcium-binding domain.
553482001878	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.25
553482001879	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.38
553482001880	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.3
553482001881	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.9
553482001882	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1
553482001883	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.4
553482001884	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.6
553482001885	HMMPfam hit to PF05031, Iron Transport-associated domain, score 1.2e-30
553482001886	1 transmembrane helix predicted for SEQ0444 by TMHMM2.0 at aa 767-786
553482001887	Cell surface heme-binding protein Shp; Region: HemeBinding_Shp; pfam11545
553482001888	2 transmembrane helices predicted for SEQ0445 by TMHMM2.0 at aa 13-32 and 271-290
553482001889	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
553482001890	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482001891	intersubunit interface [polypeptide binding]; other site
553482001892	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001893	HMMPfam hit to PF01497, Periplasmic binding protein, score 3.5e-29
553482001894	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482001895	ABC-ATPase subunit  interface; other site
553482001896	dimer interface [polypeptide binding]; other site
553482001897	putative PBP binding regions; other site
553482001898	9 transmembrane helices predicted for SEQ0447 by TMHMM2.0 at aa 21-43, 69-91, 103-122, 126-148, 155-177, 199-221, 249-271, 286-303 and 310-332
553482001899	HMMPfam hit to PF01032, FecCD transport family, score 1.1e-86
553482001900	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001901	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
553482001902	ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea.  Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC...; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
553482001903	Walker A/P-loop; other site
553482001904	ATP binding site [chemical binding]; other site
553482001905	Q-loop/lid; other site
553482001906	ABC transporter signature motif; other site
553482001907	Walker B; other site
553482001908	D-loop; other site
553482001909	H-loop/switch region; other site
553482001910	HMMPfam hit to PF00005, ABC transporter, score 6.7e-49
553482001911	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001912	PS00211 ABC transporters family signature.
553482001913	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
553482001914	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482001915	Walker A/P-loop; other site
553482001916	ATP binding site [chemical binding]; other site
553482001917	Q-loop/lid; other site
553482001918	ABC transporter signature motif; other site
553482001919	Walker B; other site
553482001920	D-loop; other site
553482001921	H-loop/switch region; other site
553482001922	5 transmembrane helices predicted for SEQ0449 by TMHMM2.0 at aa 29-51, 66-88, 143-165, 169-188 and 260-282
553482001923	PS00041 Bacterial regulatory proteins, araC family signature.
553482001924	HMMPfam hit to PF00005, ABC transporter, score 7.1e-40
553482001925	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001926	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001927	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482001928	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482001929	Walker A/P-loop; other site
553482001930	ATP binding site [chemical binding]; other site
553482001931	Q-loop/lid; other site
553482001932	ABC transporter signature motif; other site
553482001933	Walker B; other site
553482001934	D-loop; other site
553482001935	H-loop/switch region; other site
553482001936	7 transmembrane helices predicted for SEQ0450 by TMHMM2.0 at aa 21-43, 56-78, 85-102, 135-157, 164-183, 248-270 and 277-299
553482001937	HMMPfam hit to PF00005, ABC transporter, score 2.8e-39
553482001938	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001939	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; cl09823
553482001940	5 transmembrane helices predicted for SEQ0451 by TMHMM2.0 at aa 10-32, 39-61, 76-98, 111-133 and 164-186
553482001941	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001942	Cobalt transport protein; Region: CbiQ; cl00463
553482001943	HMMPfam hit to PF02361, Cobalt transport protein, score 4.7e-05
553482001944	4 transmembrane helices predicted for SEQ0452 by TMHMM2.0 at aa 20-42, 47-69, 76-98 and 113-131
553482001945	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
553482001946	Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota.  The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed.  This ABC...; Region: ABC_cobalt_CbiO_domain1; cd03225
553482001947	Walker A/P-loop; other site
553482001948	ATP binding site [chemical binding]; other site
553482001949	Q-loop/lid; other site
553482001950	ABC transporter signature motif; other site
553482001951	Walker B; other site
553482001952	D-loop; other site
553482001953	H-loop/switch region; other site
553482001954	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482001955	Walker A/P-loop; other site
553482001956	ATP binding site [chemical binding]; other site
553482001957	ABC transporter; Region: ABC_tran; pfam00005
553482001958	Q-loop/lid; other site
553482001959	ABC transporter signature motif; other site
553482001960	Walker B; other site
553482001961	D-loop; other site
553482001962	H-loop/switch region; other site
553482001963	HMMPfam hit to PF00005, ABC transporter, score 4.8e-43
553482001964	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
553482001965	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001966	PS00211 ABC transporters family signature.
553482001967	HMMPfam hit to PF00005, ABC transporter, score 1.8e-30
553482001968	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001969	PS00211 ABC transporters family signature.
553482001970	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
553482001971	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
553482001972	generic binding surface II; other site
553482001973	ssDNA binding site; other site
553482001974	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482001975	ATP binding site [chemical binding]; other site
553482001976	putative Mg++ binding site [ion binding]; other site
553482001977	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482001978	nucleotide binding region [chemical binding]; other site
553482001979	ATP-binding site [chemical binding]; other site
553482001980	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.4e-34
553482001981	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001982	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.9e-21
553482001983	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
553482001984	active site
553482001985	homotetramer interface [polypeptide binding]; other site
553482001986	homodimer interface [polypeptide binding]; other site
553482001987	HMMPfam hit to PF00710, Asparaginase, score 2.3e-142
553482001988	PS00144 Asparaginase / glutaminase active site signature 1.
553482001989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482001990	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482001991	active site
553482001992	motif I; other site
553482001993	motif II; other site
553482001994	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482001995	MazG nucleotide pyrophosphohydrolase domain; Region: MazG; cl00345
553482001996	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 4.2e-05
553482001997	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.1e-10
553482001998	PS01228 Hypothetical cof family signature 1.
553482001999	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 2.3e-80
553482002000	Predicted helix-turn-helix motif with score 986.000, SD 2.55 at aa 71-92, sequence LTRDKVLYQNQLPKSTIYKIIR
553482002001	PS01229 Hypothetical cof family signature 2.
553482002002	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
553482002003	Ligand Binding Site [chemical binding]; other site
553482002004	HMMPfam hit to PF00582, Universal stress protein family, score 9.6e-21
553482002005	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
553482002006	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482002007	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482002008	homodimer interface [polypeptide binding]; other site
553482002009	catalytic residue [active]
553482002010	HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.2e-45
553482002011	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012
553482002012	transcriptional repressor CodY; Validated; Region: PRK04158
553482002013	CodY GAF-like domain; Region: CodY; pfam06018
553482002014	Helix-turn-helix domains; Region: HTH; cl00088
553482002015	HMMPfam hit to PF06018, CodY GAF-like domain, score 4.3e-121
553482002016	HMMPfam hit to PF08279, HTH domain, score 0.00042
553482002017	HMMPfam hit to PF08222, CodY helix-turn-helix domain, score 3.5e-38
553482002018	Predicted helix-turn-helix motif with score 1428.000, SD 4.05 at aa 205-226, sequence LTASVIADRIGITRSVIVNALR
553482002019	Isochorismatase family; Region: Isochorismatase; pfam00857
553482002020	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
553482002021	catalytic triad [active]
553482002022	conserved cis-peptide bond; other site
553482002023	HMMPfam hit to PF00857, Isochorismatase family, score 1e-16
553482002024	Glu-tRNAGln amidotransferase C subunit; Region: Glu-tRNAGln; cl00495
553482002025	HMMPfam hit to PF02686, Glu-tRNAGln amidotransferase C subunit, score 3.3e-14
553482002026	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
553482002027	Amidase; Region: Amidase; cl11426
553482002028	HMMPfam hit to PF01425, Amidase, score 1.4e-184
553482002029	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
553482002030	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
553482002031	GatB domain; Region: GatB_Yqey; cl11497
553482002032	HMMPfam hit to PF02934, PET112 family, N terminal region, score 1.5e-143
553482002033	HMMPfam hit to PF01162, PET112 family, C terminal region, score 2.8e-29
553482002034	HMMPfam hit to PF02637, GatB/Yqey domain, score 1.9e-58
553482002035	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
553482002036	EamA-like transporter family; Region: EamA; cl01037
553482002037	10 transmembrane helices predicted for SEQ0464 by TMHMM2.0 at aa 7-29, 33-55, 75-94, 99-118, 125-147, 152-174, 183-205, 215-237, 250-267 and 277-296
553482002038	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.6e-12
553482002039	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002040	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.3e-16
553482002041	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
553482002042	2 transmembrane helices predicted for SEQ0465 by TMHMM2.0 at aa 2-19 and 53-75
553482002043	HMMPfam hit to PF04226, Transglycosylase associated protein, score 1.8e-12
553482002044	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
553482002045	1 transmembrane helix predicted for SEQ0466 by TMHMM2.0 at aa 17-39
553482002046	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
553482002047	HMMPfam hit to PF01842, ACT domain, score 0.0033
553482002048	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
553482002049	HMMPfam hit to PF05167, Uncharacterized ACR (DUF711), score 2.2e-270
553482002050	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002051	catalytic core [active]
553482002052	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002053	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.5e-37
553482002054	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
553482002055	1 transmembrane helix predicted for SEQ0470 by TMHMM2.0 at aa 7-26
553482002056	HMMPfam hit to PF02557, D-alanyl-D-alanine carboxypeptidase, score 1.8e-50
553482002057	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482002058	1 transmembrane helix predicted for SEQ0471 by TMHMM2.0 at aa 7-29
553482002059	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 0.002
553482002060	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
553482002061	HrcA protein C terminal domain; Region: HrcA; pfam01628
553482002062	HMMPfam hit to PF01628, HrcA protein C terminal domain, score 1.8e-52
553482002063	HMMPfam hit to PF02809, no description, score 0.59
553482002064	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
553482002065	dimer interface [polypeptide binding]; other site
553482002066	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
553482002067	HMMPfam hit to PF01025, GrpE, score 2.9e-59
553482002068	PS01071 grpE protein signature.
553482002069	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
553482002070	HMMPfam hit to PF00012, Hsp70 protein, score 0
553482002071	PS00297 Heat shock hsp70 proteins family signature 1.
553482002072	PS00329 Heat shock hsp70 proteins family signature 2.
553482002073	PS01036 Heat shock hsp70 proteins family signature 3.
553482002074	chaperone protein DnaJ; Provisional; Region: PRK14276
553482002075	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
553482002076	HSP70 interaction site [polypeptide binding]; other site
553482002077	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
553482002078	substrate binding site [polypeptide binding]; other site
553482002079	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
553482002080	Zn binding sites [ion binding]; other site
553482002081	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
553482002082	dimer interface [polypeptide binding]; other site
553482002083	HMMPfam hit to PF00226, DnaJ domain, score 6.7e-33
553482002084	PS00636 Nt-dnaJ domain signature.
553482002085	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482002086	HMMPfam hit to PF00684, DnaJ central domain (4 repeats), score 2.7e-33
553482002087	PS00637 CXXCXGXG dnaJ domain signature.
553482002088	PS00190 Cytochrome c family heme-binding site signature.
553482002089	PS00190 Cytochrome c family heme-binding site signature.
553482002090	HMMPfam hit to PF01556, DnaJ C terminal region, score 2.5e-66
553482002091	enoyl-CoA hydratase; Provisional; Region: PRK07260
553482002092	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
553482002093	substrate binding site [chemical binding]; other site
553482002094	oxyanion hole (OAH) forming residues; other site
553482002095	trimer interface [polypeptide binding]; other site
553482002096	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.9e-23
553482002097	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482002098	Helix-turn-helix domains; Region: HTH; cl00088
553482002099	HMMPfam hit to PF03965, Penicillinase repressor, score 0.0016
553482002100	HMMPfam hit to PF01047, MarR family, score 2.9e-19
553482002101	Predicted helix-turn-helix motif with score 1065.000, SD 2.81 at aa 50-71, sequence VTPSDIARELMVTLGTVTTSLN
553482002102	PS00215 Mitochondrial energy transfer proteins signature.
553482002103	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
553482002104	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
553482002105	dimer interface [polypeptide binding]; other site
553482002106	active site
553482002107	CoA binding pocket [chemical binding]; other site
553482002108	HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 7.3e-47
553482002109	HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 5.3e-45
553482002110	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482002111	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 5.1e-12
553482002112	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
553482002113	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
553482002114	FMN binding site [chemical binding]; other site
553482002115	substrate binding site [chemical binding]; other site
553482002116	putative catalytic residue [active]
553482002117	HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 1.3e-107
553482002118	PS00912 Dihydroorotate dehydrogenase signature 2.
553482002119	Acyl transferase domain; Region: Acyl_transf_1; cl08282
553482002120	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
553482002121	HMMPfam hit to PF00698, Acyl transferase domain, score 2.4e-16
553482002122	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
553482002123	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
553482002124	NAD(P) binding site [chemical binding]; other site
553482002125	homotetramer interface [polypeptide binding]; other site
553482002126	homodimer interface [polypeptide binding]; other site
553482002127	active site
553482002128	HMMPfam hit to PF00106, short chain dehydrogenase, score 4e-47
553482002129	HMMPfam hit to PF07993, Male sterility protein, score 0.0008
553482002130	PS00061 Short-chain dehydrogenases/reductases family signature.
553482002131	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482002132	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
553482002133	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
553482002134	dimer interface [polypeptide binding]; other site
553482002135	active site
553482002136	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.8e-65
553482002137	PS00606 Beta-ketoacyl synthases active site.
553482002138	PS00098 Thiolases acyl-enzyme intermediate signature.
553482002139	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 6.3e-59
553482002140	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
553482002141	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
553482002142	carboxyltransferase (CT) interaction site; other site
553482002143	biotinylation site [posttranslational modification]; other site
553482002144	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 7.4e-25
553482002145	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
553482002146	HMMPfam hit to PF07977, FabA-like domain, score 1.5e-68
553482002147	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
553482002148	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482002149	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482002150	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; cl08365
553482002151	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 6.9e-43
553482002152	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 4.3e-95
553482002153	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482002154	PS00238 Visual pigments (opsins) retinal binding site.
553482002155	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482002156	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 2.4e-53
553482002157	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
553482002158	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl15772
553482002159	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl15772
553482002160	HMMPfam hit to PF03255, Acetyl co-enzyme A carboxylase carboxyltrans, score 7.3e-22
553482002161	seryl-tRNA synthetase; Provisional; Region: PRK05431
553482002162	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
553482002163	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme bound...; Region: SerRS_core; cd00770
553482002164	dimer interface [polypeptide binding]; other site
553482002165	active site
553482002166	motif 1; other site
553482002167	motif 2; other site
553482002168	motif 3; other site
553482002169	HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 9.3e-70
553482002170	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482002171	HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain, score 2.4e-44
553482002172	OpgC protein; Region: OpgC_C; cl00792
553482002173	Acyltransferase family; Region: Acyl_transf_3; pfam01757
553482002174	9 transmembrane helices predicted for SEQ0490 by TMHMM2.0 at aa 31-53, 65-87, 102-124, 131-150, 165-183, 190-209, 213-235, 242-262 and 282-304
553482002175	Domain of unknown function (DUF956); Region: DUF956; cl01917
553482002176	HMMPfam hit to PF06115, Domain of unknown function (DUF956), score 2.8e-75
553482002177	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
553482002178	4 transmembrane helices predicted for SEQ0492 by TMHMM2.0 at aa 125-147, 181-203, 260-277 and 284-302
553482002179	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
553482002180	7 transmembrane helices predicted for SEQ0493 by TMHMM2.0 at aa 4-21, 33-55, 65-87, 99-121, 144-166, 187-206 and 221-243
553482002181	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 2.2e-137
553482002182	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
553482002183	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482002184	active pocket/dimerization site; other site
553482002185	active site
553482002186	phosphorylation site [posttranslational modification]
553482002187	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482002188	active site
553482002189	phosphorylation site [posttranslational modification]
553482002190	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 7.2e-87
553482002191	HMMPfam hit to PF03610, PTS system fructose IIA component, score 9.2e-55
553482002192	CDS contains a frameshift after codon 128. Frameshift occurs at a poly T pentamer. Similar to Streptococcus pyogenes serotype M18 hypothetical protein Spym18_1809 UniProt:Q8NZP0 (EMBL:AE010088 (270 aa) fasta scores: E()=3.1e-86, 83.704% id in 270 aa
553482002193	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 5.2e-06
553482002194	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
553482002195	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; cl00668
553482002196	HMMPfam hit to PF00860, Permease family, score 3.8e-09
553482002197	10 transmembrane helices predicted for SEQ0497 by TMHMM2.0 at aa 20-42, 49-71, 91-113, 125-147, 196-218, 225-247, 257-276, 379-413, 433-455 and 468-485
553482002198	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
553482002199	HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079, score 5.1e-39
553482002200	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002201	putative acetyltransferase YhhY; Provisional; Region: PRK10140
553482002202	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482002203	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.9e-11
553482002204	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
553482002205	1 transmembrane helix predicted for SEQ0500 by TMHMM2.0 at aa 7-29
553482002206	HMMPfam hit to PF03816, Cell envelope-related transcriptional a, score 5.6e-79
553482002207	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
553482002208	HIT family signature motif; other site
553482002209	catalytic residue [active]
553482002210	HMMPfam hit to PF01230, HIT domain, score 1.7e-38
553482002211	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482002212	This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity.  In bacteria and archaea, these transporters usually include an ATP-binding...; Region: ABC_DR_subfamily_A; cd03230
553482002213	Walker A/P-loop; other site
553482002214	ATP binding site [chemical binding]; other site
553482002215	Q-loop/lid; other site
553482002216	ABC transporter signature motif; other site
553482002217	Walker B; other site
553482002218	D-loop; other site
553482002219	H-loop/switch region; other site
553482002220	HMMPfam hit to PF00005, ABC transporter, score 2e-44
553482002221	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002222	PS00211 ABC transporters family signature.
553482002223	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
553482002224	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
553482002225	HMMPfam hit to PF05975, Bacterial ABC transporter protein EcsB, score 5.2e-146
553482002226	8 transmembrane helices predicted for SEQ0507 by TMHMM2.0 at aa 19-41, 56-78, 103-122, 126-148, 229-248, 253-275, 296-313 and 317-335
553482002227	Phosphotransferase enzyme family; Region: APH; pfam01636
553482002228	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: APH_ChoK_like; cd05120
553482002229	active site
553482002230	ATP binding site [chemical binding]; other site
553482002231	substrate binding site [chemical binding]; other site
553482002232	HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 3.1e-31
553482002233	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482002234	S-adenosylmethionine binding site [chemical binding]; other site
553482002235	HMMPfam hit to PF02390, methyltransferase, score 7.6e-57
553482002236	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M1 phi5005.3 integrase UniProt:Q48X40 (EMBL:CP000017 (359 aa) fasta scores: E()=7.5e-08, 79.310% id in 29 aa
553482002237	gene remnant. Similar to an internal region of Streptococcus pyogenes serotype M6 transposase UniProt:Q5XBP0 (EMBL:CP000003 (74 aa) fasta scores: E()=3.8e-06, 73.077% id in 26 aa
553482002238	gene remnant. Similar to the C-terminal region of Lactobacillus plantarum integral membrane protein UniProt:Q88TN7 (EMBL:AL935260 (183 aa) fasta scores: E()=0.5, 42.222% id in 45 aa
553482002239	1 transmembrane helix predicted for SEQ0511 by TMHMM2.0 at aa 20-42
553482002240	gene remnant. CDS lacks appropriate translational start site
553482002241	HMMPfam hit to PF02576, Uncharacterised BCR, YhbC family COG0779, score 3.9e-53
553482002242	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
553482002243	NusA N-terminal domain; Region: NusA_N; pfam08529
553482002244	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
553482002245	RNA binding site [nucleotide binding]; other site
553482002246	homodimer interface [polypeptide binding]; other site
553482002247	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cl00098
553482002248	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
553482002249	G-X-X-G motif; other site
553482002250	HMMPfam hit to PF08529, NusA N-terminal domain, score 1.2e-56
553482002251	HMMPfam hit to PF00575, S1 RNA binding domain, score 0.0001
553482002252	HMMPfam hit to PF00013, KH domain, score 0.029
553482002253	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
553482002254	putative RNA binding cleft [nucleotide binding]; other site
553482002255	HMMPfam hit to PF04296, Protein of unknown function (DUF448), score 1.6e-34
553482002256	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
553482002257	HMMPfam hit to PF01248, Ribosomal protein L7Ae/L30e/S12e/Gadd4, score 2.1e-21
553482002258	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
553482002259	translation initiation factor IF-2; Region: IF-2; TIGR00487
553482002260	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
553482002261	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
553482002262	G1 box; other site
553482002263	putative GEF interaction site [polypeptide binding]; other site
553482002264	GTP/Mg2+ binding site [chemical binding]; other site
553482002265	Switch I region; other site
553482002266	G2 box; other site
553482002267	G3 box; other site
553482002268	Switch II region; other site
553482002269	G4 box; other site
553482002270	G5 box; other site
553482002271	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
553482002272	Translation-initiation factor 2; Region: IF-2; pfam11987
553482002273	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
553482002274	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 2.5e-13
553482002275	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 3.6e-22
553482002276	PS00215 Mitochondrial energy transfer proteins signature.
553482002277	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 9.9e-55
553482002278	HMMPfam hit to PF01926, GTPase of unknown function, score 3.8e-08
553482002279	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002280	HMMPfam hit to PF03144, Elongation factor Tu domain, score 6.1e-11
553482002281	Ribosome-binding factor A; Region: RBFA; cl00542
553482002282	HMMPfam hit to PF02033, Ribosome-binding factor A, score 2.8e-27
553482002283	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482002284	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
553482002285	HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 5e-29
553482002286	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
553482002287	Helix-turn-helix domains; Region: HTH; cl00088
553482002288	HMMPfam hit to PF03965, Penicillinase repressor, score 9.3e-45
553482002289	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
553482002290	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
553482002291	metal-binding site [ion binding]
553482002292	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
553482002293	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482002294	HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.7e-15
553482002295	PS01047 Heavy-metal-associated domain.
553482002296	8 transmembrane helices predicted for SEQ0522 by TMHMM2.0 at aa 95-117, 127-144, 165-187, 192-214, 348-370, 380-402, 689-711 and 715-737
553482002297	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002298	HMMPfam hit to PF00122, E1-E2 ATPase, score 1.2e-94
553482002299	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002300	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.2e-35
553482002301	PS00154 E1-E2 ATPases phosphorylation site.
553482002302	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
553482002303	1 transmembrane helix predicted for SEQ0524 by TMHMM2.0 at aa 45-62
553482002304	LemA family; Region: LemA; cl00742
553482002305	HMMPfam hit to PF04011, LemA family, score 1.2e-08
553482002306	2 transmembrane helices predicted for SEQ0525 by TMHMM2.0 at aa 5-20 and 136-158
553482002307	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482002308	Helix-turn-helix domains; Region: HTH; cl00088
553482002309	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482002310	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 5.3e-67
553482002311	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 9.1e-15
553482002312	HMMPfam hit to PF08279, HTH domain, score 0.0011
553482002313	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
553482002314	HMMPfam hit to PF02502, Ribose/Galactose Isomerase, score 9.3e-45
553482002315	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
553482002316	HMMPfam hit to PF02502, Ribose/Galactose Isomerase, score 3.3e-42
553482002317	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
553482002318	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
553482002319	putative substrate binding site [chemical binding]; other site
553482002320	putative ATP binding site [chemical binding]; other site
553482002321	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 2.1e-58
553482002322	PS00583 pfkB family of carbohydrate kinases signature 1.
553482002323	PS00584 pfkB family of carbohydrate kinases signature 2.
553482002324	gene remnant. The CDS appears to be truncated at the C-terminus. Similar to the N-terminal region of Streptococcus pyogenes serotype M18 tagatose 1,6-diphosphate aldolase 1 LacD1 UniProt:P63704 (EMBL:AE010082 (325 aa) fasta scores: E()=2.2e-20, 77.528% id in 89 aa
553482002325	gene remnant. The CDS appears to be truncated at the N-terminus. Similar to C-terminus of Staphylococcus aureus (strain MSSA476) 6-phospho-beta-galactosidase LacG UniProt:Q6G7C5 (EMBL:BX571857 (470 aa) fasta scores: E()=5.7e-41, 80.597% id in 134 aa
553482002326	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 3.8e-08
553482002327	Domain of unknown function (DUF4300); Region: DUF4300; pfam14133
553482002328	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002329	Predicted membrane protein [Function unknown]; Region: COG2860
553482002330	UPF0126 domain; Region: UPF0126; pfam03458
553482002331	UPF0126 domain; Region: UPF0126; pfam03458
553482002332	6 transmembrane helices predicted for SEQ0533 by TMHMM2.0 at aa 5-27, 32-54, 67-86, 90-112, 119-141 and 161-183
553482002333	HMMPfam hit to PF03458, UPF0126 domain, score 1.7e-27
553482002334	HMMPfam hit to PF03458, UPF0126 domain, score 6.5e-33
553482002335	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482002336	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482002337	active site
553482002338	motif I; other site
553482002339	motif II; other site
553482002340	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482002341	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00061
553482002342	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 9.3e-08
553482002343	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 7.6e-78
553482002344	PS01229 Hypothetical cof family signature 2.
553482002345	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482002346	Helix-turn-helix domains; Region: HTH; cl00088
553482002347	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.3e-06
553482002348	Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 45-66, sequence ITISELVARAGVSRNAFYRNYS
553482002349	Uncharacterized protein, DegV family COG1307; Region: DegV; cl00577
553482002350	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 3.9e-67
553482002351	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
553482002352	1 transmembrane helix predicted for SEQ0537 by TMHMM2.0 at aa 9-31
553482002353	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
553482002354	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
553482002355	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
553482002356	PhoU domain; Region: PhoU; pfam01895
553482002357	PhoU domain; Region: PhoU; pfam01895
553482002358	8 transmembrane helices predicted for SEQ0538 by TMHMM2.0 at aa 4-21, 41-60, 65-87, 99-121, 131-148, 173-195, 210-232 and 245-267
553482002359	HMMPfam hit to PF02690, Na+/Pi-cotransporter, score 1.1e-74
553482002360	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002361	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
553482002362	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
553482002363	active site
553482002364	dimer interface [polypeptide binding]; other site
553482002365	HMMPfam hit to PF01979, Amidohydrolase family, score 9e-06
553482002366	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
553482002367	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
553482002368	active site
553482002369	catalytic tetrad [active]
553482002370	HMMPfam hit to PF00248, Aldo/keto reductase family, score 7.6e-109
553482002371	PS00798 Aldo/keto reductase family signature 1.
553482002372	PS00062 Aldo/keto reductase family signature 2.
553482002373	PS00063 Aldo/keto reductase family active site signature.
553482002374	gene remnant. Similar to an internal region of Lactobacillus salivarius subsp. salivarius (strain ucc118) ABC transporter, ATP-binding protein UniProt:Q1WV92 (EMBL:CP000233 (661 aa) fasta scores: E()=0.0006, 48.485% id in 66 aa
553482002375	Phospholipid methyltransferase; Region: PEMT; cl00763
553482002376	3 transmembrane helices predicted for SEQ0542 by TMHMM2.0 at aa 35-52, 59-81 and 122-144
553482002377	HMMPfam hit to PF04140, Isoprenylcysteine carboxyl methyltransferase, score 3.1e-47
553482002378	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
553482002379	dimer interface [polypeptide binding]; other site
553482002380	motif 1; other site
553482002381	active site
553482002382	motif 2; other site
553482002383	motif 3; other site
553482002384	HMMPfam hit to PF02091, Glycyl-tRNA synthetase alpha subunit, score 2.8e-219
553482002385	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482002386	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
553482002387	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
553482002388	HMMPfam hit to PF02092, Glycyl-tRNA synthetase beta subunit, score 5.2e-226
553482002389	HMMPfam hit to PF05746, DALR anticodon binding domain, score 0.00022
553482002390	Bacterial protein of unknown function (DUF896); Region: DUF896; cl01722
553482002391	HMMPfam hit to PF05979, Bacterial protein of unknown function (DUF89, score 2.9e-42
553482002392	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
553482002393	putative FMN binding site [chemical binding]; other site
553482002394	NADPH bind site [chemical binding]; other site
553482002395	bacteriocin biosynthesis cyclodehydratase, SagC family; Region: cyclo_dehy_ocin; TIGR03603
553482002396	Uncharacterized conserved protein [Function unknown]; Region: COG1944; cl09146
553482002397	YcaO-like family; Region: YcaO; pfam02624
553482002398	HMMPfam hit to PF02624, YcaO-like family, score 1.2e-07
553482002399	CAAX protease self-immunity; Region: Abi; cl00558
553482002400	5 transmembrane helices predicted for SEQ0550 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 147-169 and 182-204
553482002401	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 0.00021
553482002402	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002403	6 transmembrane helices predicted for SEQ0551 by TMHMM2.0 at aa 4-21, 42-64, 84-106, 134-156, 160-182 and 189-211
553482002404	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482002405	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482002406	Walker A/P-loop; other site
553482002407	ATP binding site [chemical binding]; other site
553482002408	Q-loop/lid; other site
553482002409	ABC transporter signature motif; other site
553482002410	Walker B; other site
553482002411	D-loop; other site
553482002412	H-loop/switch region; other site
553482002413	HMMPfam hit to PF00005, ABC transporter, score 1.8e-66
553482002414	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002415	PS00211 ABC transporters family signature.
553482002416	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
553482002417	ABC-2 type transporter; Region: ABC2_membrane; cl11417
553482002418	6 transmembrane helices predicted for SEQ0553 by TMHMM2.0 at aa 20-39, 182-204, 225-247, 262-284, 289-311 and 345-367
553482002419	HMMPfam hit to PF01061, ABC-2 type transporter, score 8.8e-07
553482002420	ABC-2 type transporter; Region: ABC2_membrane; cl11417
553482002421	6 transmembrane helices predicted for SEQ0554 by TMHMM2.0 at aa 20-42, 182-204, 225-247, 257-279, 292-314 and 345-367
553482002422	HMMPfam hit to PF01061, ABC-2 type transporter, score 1.2e-13
553482002423	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002424	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482002425	TQXA domain; Region: TQXA_dom; TIGR03934
553482002426	2 transmembrane helices predicted for SEQ0555 by TMHMM2.0 at aa 9-31 and 385-404
553482002427	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 5.6e-09
553482002428	gene remnant. CDS lacks an N-terminal signal sequence, therefore it will not be processed correctly. Similar to the C-terminal region of Streptococcus equi subsp. equi collagen-like protein G SclG UniProt:Q1I0L6 (EMBL:DQ158083 (397 aa) fasta scores: E()=4.6e-25, 36.929% id in 241 aa
553482002429	1 transmembrane helix predicted for SEQ0556 by TMHMM2.0 at aa 395-414
553482002430	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.6e-11
553482002431	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.3e-12
553482002432	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002433	CutC family; Region: CutC; cl01218
553482002434	HMMPfam hit to PF03932, CutC family, score 2.5e-116
553482002435	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482002436	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.4e-05
553482002437	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
553482002438	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
553482002439	DNA binding site [nucleotide binding]
553482002440	active site
553482002441	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, score 2e-39
553482002442	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
553482002443	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
553482002444	ArsC family; Region: ArsC; pfam03960
553482002445	putative ArsC-like catalytic residues; other site
553482002446	putative TRX-like catalytic residues [active]
553482002447	HMMPfam hit to PF03960, ArsC family, score 1.8e-29
553482002448	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
553482002449	active site
553482002450	DNA binding site [nucleotide binding]
553482002451	putative phosphate binding site [ion binding]; other site
553482002452	putative catalytic site [active]
553482002453	metal binding site A [ion binding]; metal-binding site
553482002454	AP binding site [nucleotide binding]; other site
553482002455	metal binding site B [ion binding]; metal-binding site
553482002456	PS00728 AP endonucleases family 1 signature 3.
553482002457	PS00726 AP endonucleases family 1 signature 1.
553482002458	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482002459	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
553482002460	putative active site [active]
553482002461	catalytic triad [active]
553482002462	PA_C5a_like: Protease-associated domain containing proteins like Streptococcus pyogenes C5a peptidase. This group contains various PA domain-containing proteins similar to S. pyogenes C5a, including, i) Vpr, a minor extracellular serine protease from...; Region: PA_C5a_like; cd02133
553482002463	putative integrin binding motif; other site
553482002464	PA/protease domain interface [polypeptide binding]; other site
553482002465	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
553482002466	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
553482002467	HMMPfam hit to PF04650, YSIRK type signal peptide, score 3.6e-07
553482002468	1 transmembrane helix predicted for SEQ0563 by TMHMM2.0 at aa 12-34
553482002469	HMMPfam hit to PF00082, Subtilase family, score 6.3e-41
553482002470	PS00136 Serine proteases, subtilase family, aspartic acid active site.
553482002471	PS00137 Serine proteases, subtilase family, histidine active site.
553482002472	HMMPfam hit to PF02225, PA domain, score 4.2e-13
553482002473	PS00138 Serine proteases, subtilase family, serine active site.
553482002474	HMMPfam hit to PF06280, Domain of Unknown Function (DUF1034), score 6.8e-46
553482002475	HMMPfam hit to PF00746, Gram positive anchor, score 8.2e-05
553482002476	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002477	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002478	3 transmembrane helices predicted for SEQ0564 by TMHMM2.0 at aa 5-27, 37-59 and 87-109
553482002479	CDS contains a frameshift around codon 182. Similar to Streptococcus equi M-like protein precursor emmszw60 UniProt:Q54071 (EMBL:U04620 (376 aa) fasta scores: E()=3.4e-14, 34.615% id in 390 aa
553482002480	1 transmembrane helix predicted for SEQ0566 by TMHMM2.0 at aa 13-35
553482002481	HMMPfam hit to PF00746, Gram positive anchor, score 1.6e-11
553482002482	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002483	1 transmembrane helix predicted for SEQ0567 by TMHMM2.0 at aa 112-134
553482002484	Protein of unknown function (DUF1275); Region: DUF1275; cl01453
553482002485	4 transmembrane helices predicted for SEQ0568 by TMHMM2.0 at aa 12-34, 65-87, 94-116 and 178-200
553482002486	HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 9e-76
553482002487	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
553482002488	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
553482002489	active site
553482002490	HIGH motif; other site
553482002491	KMSKS motif; other site
553482002492	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
553482002493	tRNA binding surface [nucleotide binding]; other site
553482002494	anticodon binding site; other site
553482002495	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
553482002496	dimer interface [polypeptide binding]; other site
553482002497	putative tRNA-binding site [nucleotide binding]; other site
553482002498	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002499	HMMPfam hit to PF01588, tRNA binding domain, score 2.8e-30
553482002500	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
553482002501	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
553482002502	dimer interface [polypeptide binding]; other site
553482002503	putative radical transfer pathway; other site
553482002504	diiron center [ion binding]; other site
553482002505	tyrosyl radical; other site
553482002506	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 3e-38
553482002507	1 transmembrane helix predicted for SEQ0570 by TMHMM2.0 at aa 170-192
553482002508	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
553482002509	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 3e-73
553482002510	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07187
553482002511	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
553482002512	Class I ribonucleotide reductase; Region: RNR_I; cd01679
553482002513	active site
553482002514	dimer interface [polypeptide binding]; other site
553482002515	catalytic residues [active]
553482002516	effector binding site; other site
553482002517	R2 peptide binding site; other site
553482002518	HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 5.4e-35
553482002519	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 2.5e-25
553482002520	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 2e-164
553482002521	PS00089 Ribonucleotide reductase large subunit signature.
553482002522	gene remnant generated by the insertion of the an IS element and subsequent recombination events
553482002523	putative transposase OrfB; Reviewed; Region: PHA02517
553482002524	HTH-like domain; Region: HTH_21; pfam13276
553482002525	Integrase core domain; Region: rve; cl01316
553482002526	Integrase core domain; Region: rve_3; cl15866
553482002527	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482002528	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482002529	Helix-turn-helix domains; Region: HTH; cl00088
553482002530	HMMPfam hit to PF01527, Transposase, score 0.00062
553482002531	HMMPfam hit to PF02178, no description, score 0.21
553482002532	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482002533	CDS is truncated by the insertion of the upstream IS element
553482002534	1 transmembrane helix predicted for SEQ0576 by TMHMM2.0 at aa 94-116
553482002535	CDS contains a frameshift after codon 13. Frameshift occurs at a poly T hexamer
553482002536	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; cl01868
553482002537	1 transmembrane helix predicted for SEQ0579 by TMHMM2.0 at aa 210-232
553482002538	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
553482002539	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482002540	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482002541	1 transmembrane helix predicted for SEQ0580 by TMHMM2.0 at aa 213-235
553482002542	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 3.4e-38
553482002543	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002544	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 2.4e-24
553482002545	Domain of unknown function (DUF4176); Region: DUF4176; cl01867
553482002549	HMMPfam hit to PF01610, Transposase, score 1.3e-06
553482002550	Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 130-151, sequence EAFTHIAAKLAISTSTVYHKLK
553482002551	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
553482002552	6 transmembrane helices predicted for SEQ0587 by TMHMM2.0 at aa 10-32, 51-73, 88-110, 130-152, 172-194 and 207-226
553482002553	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembran, score 1.8e-56
553482002554	PS00086 Cytochrome P450 cysteine heme-iron ligand signature.
553482002555	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
553482002556	catalytic residues [active]
553482002557	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002558	HMMPfam hit to PF08534, Redoxin, score 1.3e-26
553482002559	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
553482002560	methionine sulfoxide reductase B; Provisional; Region: PRK00222; cl15841
553482002561	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
553482002562	1 transmembrane helix predicted for SEQ0589 by TMHMM2.0 at aa 7-29
553482002563	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 1.4e-83
553482002564	HMMPfam hit to PF01641, SelR domain, score 2.7e-81
553482002565	Response regulator receiver domain; Region: Response_reg; pfam00072
553482002566	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482002567	active site
553482002568	phosphorylation site [posttranslational modification]
553482002569	intermolecular recognition site; other site
553482002570	dimerization interface [polypeptide binding]; other site
553482002571	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
553482002572	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482002573	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.8e-36
553482002574	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 8.7e-06
553482002575	Predicted helix-turn-helix motif with score 1473.000, SD 4.20 at aa 159-180, sequence LTLKSLSSQLGFSPNYLSVLIK
553482002576	PS00041 Bacterial regulatory proteins, araC family signature.
553482002577	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2e-12
553482002578	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482002579	Cache domain; Region: Cache_1; pfam02743
553482002580	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
553482002581	dimerization interface [polypeptide binding]; other site
553482002582	Histidine kinase; Region: His_kinase; pfam06580
553482002583	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482002584	ATP binding site [chemical binding]; other site
553482002585	Mg2+ binding site [ion binding]; other site
553482002586	G-X-G motif; other site
553482002587	2 transmembrane helices predicted for SEQ0591 by TMHMM2.0 at aa 10-29 and 281-303
553482002588	HMMPfam hit to PF02743, Cache domain, score 1.6e-17
553482002589	HMMPfam hit to PF00672, HAMP domain, score 3.2e-13
553482002590	HMMPfam hit to PF06580, Histidine kinase, score 1e-42
553482002591	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP9, score 6e-11
553482002592	Protein of unknown function (DUF419); Region: DUF419; cl15265
553482002593	HMMPfam hit to PF04237, Protein of unknown function (DUF419), score 1.5e-37
553482002594	PS00213 Lipocalin signature.
553482002595	B3/4 domain; Region: B3_4; cl11458
553482002596	HMMPfam hit to PF03483, B3/4 domain, score 2.6e-26
553482002597	Uncharacterized conserved protein [Function unknown]; Region: COG3760
553482002598	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
553482002599	putative deacylase active site [active]
553482002600	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 8e-08
553482002601	Arginine repressor [Transcription]; Region: ArgR; COG1438
553482002602	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482002603	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
553482002604	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 2.7e-25
553482002605	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 3.8e-24
553482002606	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
553482002607	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
553482002608	ligand binding site [chemical binding]; other site
553482002609	flexible hinge region; other site
553482002610	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
553482002611	putative switch regulator; other site
553482002612	non-specific DNA interactions [nucleotide binding]; other site
553482002613	DNA binding site [nucleotide binding]
553482002614	sequence specific DNA binding site [nucleotide binding]; other site
553482002615	putative cAMP binding site [chemical binding]; other site
553482002616	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 2.1e-17
553482002617	HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 3.4e-07
553482002618	Predicted helix-turn-helix motif with score 2209.000, SD 6.71 at aa 177-198, sequence LTTTDIAQMSGTTRETVSHVFR
553482002619	Amidinotransferase; Region: Amidinotransf; cl12043
553482002620	HMMPfam hit to PF02274, Amidinotransferase, score 3.2e-204
553482002621	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482002622	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482002623	Coenzyme A binding pocket [chemical binding]; other site
553482002624	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.4e-14
553482002625	ornithine carbamoyltransferase; Validated; Region: PRK02102
553482002626	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
553482002627	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482002628	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 8.3e-70
553482002629	PS00097 Aspartate and ornithine carbamoyltransferases signature.
553482002630	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 2.2e-79
553482002631	C4-dicarboxylate anaerobic carrier; Region: DcuC; cl15356
553482002632	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.8e-242
553482002633	13 transmembrane helices predicted for SEQ0600 by TMHMM2.0 at aa 13-35, 79-98, 119-138, 148-170, 175-197, 201-223, 261-279, 312-334, 341-363, 378-400, 407-429, 444-466 and 479-496
553482002634	hypothetical protein; Provisional; Region: PRK07205
553482002635	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
553482002636	active site
553482002637	metal binding site [ion binding]; metal-binding site
553482002638	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 7e-24
553482002639	Predicted helix-turn-helix motif with score 1077.000, SD 2.86 at aa 422-443, sequence IVLADAYRAMDIYAEAIYRLTR
553482002640	carbamate kinase; Reviewed; Region: PRK12686
553482002641	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
553482002642	putative substrate binding site [chemical binding]; other site
553482002643	nucleotide binding site [chemical binding]; other site
553482002644	nucleotide binding site [chemical binding]; other site
553482002645	homodimer interface [polypeptide binding]; other site
553482002646	HMMPfam hit to PF00696, Amino acid kinase family, score 3.7e-97
553482002647	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
553482002648	dimer interface [polypeptide binding]; other site
553482002649	active site
553482002650	HMMPfam hit to PF03590, Aspartate-ammonia ligase, score 6.1e-179
553482002651	Methyltransferase domain; Region: Methyltransf_31; pfam13847
553482002652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482002653	S-adenosylmethionine binding site [chemical binding]; other site
553482002654	HMMPfam hit to PF03602, Conserved hypothetical protein, score 5.3e-91
553482002655	PS00092 N-6 Adenine-specific DNA methylases signature.
553482002656	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
553482002657	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
553482002658	active site
553482002659	(T/H)XGH motif; other site
553482002660	HMMPfam hit to PF01467, Cytidylyltransferase, score 5.3e-25
553482002661	HMMPfam hit to PF08218, Citrate lyase ligase C-terminal domain, score 0.0018
553482002662	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
553482002663	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
553482002664	protein binding site [polypeptide binding]; other site
553482002665	1 transmembrane helix predicted for SEQ0606 by TMHMM2.0 at aa 9-31
553482002666	Protein of unknown function (DUF1027); Region: DUF1027; cl09961
553482002667	HMMPfam hit to PF06265, Protein of unknown function (DUF1027), score 9.8e-57
553482002668	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
553482002669	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482002670	FeS/SAM binding site; other site
553482002671	6 transmembrane helices predicted for SEQ0610 by TMHMM2.0 at aa 4-21, 71-93, 108-130, 132-154, 169-186 and 193-212
553482002672	HMMPfam hit to PF01478, Type IV leader peptidase family, score 7.6e-11
553482002673	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002674	Ferritin-like domain; Region: Ferritin; pfam00210
553482002675	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
553482002676	dimerization interface [polypeptide binding]; other site
553482002677	DPS ferroxidase diiron center [ion binding]; other site
553482002678	ion pore; other site
553482002679	HMMPfam hit to PF00210, Ferritin-like domain, score 1.5e-33
553482002680	PS00818 Dps protein family signature 1.
553482002681	Bacterial protein of unknown function (DUF910); Region: DUF910; cl11543
553482002682	HMMPfam hit to PF06014, Bacterial protein of unknown function (DUF91, score 2e-35
553482002683	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
553482002684	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
553482002685	HMMPfam hit to PF00480, ROK family, score 3e-42
553482002686	PS01125 ROK family signature.
553482002687	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002688	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
553482002689	active site residue [active]
553482002690	1 transmembrane helix predicted for SEQ0614 by TMHMM2.0 at aa 4-26
553482002691	HMMPfam hit to PF00581, Rhodanese-like domain, score 8.3e-07
553482002692	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
553482002693	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
553482002694	G1 box; other site
553482002695	putative GEF interaction site [polypeptide binding]; other site
553482002696	GTP/Mg2+ binding site [chemical binding]; other site
553482002697	Switch I region; other site
553482002698	G2 box; other site
553482002699	G3 box; other site
553482002700	Switch II region; other site
553482002701	G4 box; other site
553482002702	G5 box; other site
553482002703	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
553482002704	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
553482002705	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.8e-68
553482002706	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002707	PS00301 GTP-binding elongation factors signature.
553482002708	HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.8e-17
553482002709	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 2.1e-27
553482002710	Protein of unknown function (DUF3165); Region: DUF3165; pfam11364
553482002711	3 transmembrane helices predicted for SEQ0616 by TMHMM2.0 at aa 2-19, 25-47 and 56-73
553482002712	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
553482002713	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482002714	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482002715	HMMPfam hit to PF08245, Mur ligase middle domain, score 1.7e-64
553482002716	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 5.3e-17
553482002717	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
553482002718	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
553482002719	active site
553482002720	homodimer interface [polypeptide binding]; other site
553482002721	HMMPfam hit to PF03033, Glycosyltransferase family, score 7.2e-38
553482002722	HMMPfam hit to PF04101, Glycosyltransferase family, score 1.5e-24
553482002723	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
553482002724	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
553482002725	Cell division protein FtsQ; Region: FtsQ; pfam03799
553482002726	1 transmembrane helix predicted for SEQ0619 by TMHMM2.0 at aa 115-137
553482002727	HMMPfam hit to PF08478, POTRA domain, FtsQ-type, score 9.8e-16
553482002728	HMMPfam hit to PF03799, Cell division protein FtsQ, score 2.6e-28
553482002729	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
553482002730	Cell division protein FtsA; Region: FtsA; cl11496
553482002731	Cell division protein FtsA; Region: FtsA; cl11496
553482002732	Domain of unknown function (DUF3484); Region: DUF3484; pfam11983
553482002733	HMMPfam hit to PF02491, Cell division protein FtsA, score 7.2e-70
553482002734	HMMPfam hit to PF02491, Cell division protein FtsA, score 4.8e-47
553482002735	cell division protein FtsZ; Validated; Region: PRK09330
553482002736	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
553482002737	nucleotide binding site [chemical binding]; other site
553482002738	SulA interaction site; other site
553482002739	HMMPfam hit to PF00091, Tubulin/FtsZ family, GTPase domain, score 4.7e-96
553482002740	PS01134 FtsZ protein signature 1.
553482002741	HMMPfam hit to PF03953, Tubulin/FtsZ family, C-terminal domain, score 7.7e-24
553482002742	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
553482002743	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
553482002744	catalytic residue [active]
553482002745	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 1.1e-07
553482002746	PS01211 Uncharacterized protein family UPF0001 signature.
553482002747	Protein of unknown function (DUF552); Region: DUF552; cl00775
553482002748	HMMPfam hit to PF04472, Protein of unknown function (DUF552), score 2.5e-45
553482002749	YGGT family; Region: YGGT; cl00508
553482002750	HMMPfam hit to PF02325, YGGT family, score 1.4e-26
553482002751	2 transmembrane helices predicted for SEQ0624 by TMHMM2.0 at aa 7-29 and 59-81
553482002752	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
553482002753	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482002754	RNA binding surface [nucleotide binding]; other site
553482002755	HMMPfam hit to PF01479, S4 domain, score 1.4e-10
553482002756	DivIVA protein; Region: DivIVA; pfam05103
553482002757	DivIVA domain; Region: DivI1A_domain; TIGR03544
553482002758	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
553482002759	HMMPfam hit to PF05103, DivIVA protein, score 8.8e-112
553482002760	isoleucyl-tRNA synthetase; Provisional; Region: ileS; PRK13804
553482002761	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482002762	active site
553482002763	HIGH motif; other site
553482002764	nucleotide binding site [chemical binding]; other site
553482002765	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
553482002766	active site
553482002767	KMSKS motif; other site
553482002768	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
553482002769	tRNA binding surface [nucleotide binding]; other site
553482002770	anticodon binding site; other site
553482002771	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 8.8e-274
553482002772	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482002773	HMMPfam hit to PF08264, Anticodon-binding domain, score 1.9e-54
553482002774	HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 8.9e-05
553482002775	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
553482002776	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
553482002777	nudix motif; other site
553482002778	HMMPfam hit to PF00293, NUDIX domain, score 7.9e-12
553482002779	PS00893 mutT domain signature.
553482002780	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
553482002781	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482002782	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
553482002783	Walker A motif; other site
553482002784	ATP binding site [chemical binding]; other site
553482002785	Walker B motif; other site
553482002786	arginine finger; other site
553482002787	UvrB/uvrC motif; Region: UVR; pfam02151
553482002788	ATP-dependent protease Clp, ATPase subunit [Posttranslational modification, protein turnover, chaperones]; Region: ClpX; COG1219
553482002789	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482002790	Walker A motif; other site
553482002791	ATP binding site [chemical binding]; other site
553482002792	Walker B motif; other site
553482002793	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
553482002794	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00022
553482002795	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.7e-99
553482002796	PS00871 Chaperonins clpA/B signature 2.
553482002797	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002798	HMMPfam hit to PF02151, UvrB/uvrC motif, score 0.00014
553482002799	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.3e-10
553482002800	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00072
553482002801	PS00870 Chaperonins clpA/B signature 1.
553482002802	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002803	Protein of unknown function (DUF1797); Region: DUF1797; cl11550
553482002804	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482002805	HMMPfam hit to PF00746, Gram positive anchor, score 1.7e-10
553482002806	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002807	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-16
553482002808	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 4.5e-10
553482002809	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
553482002810	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482002811	dimer interface [polypeptide binding]; other site
553482002812	conserved gate region; other site
553482002813	putative PBP binding loops; other site
553482002814	ABC-ATPase subunit interface; other site
553482002815	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.7e-26
553482002816	3 transmembrane helices predicted for SEQ0634 by TMHMM2.0 at aa 15-37, 50-72 and 196-218
553482002817	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002818	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482002819	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482002820	HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, repectively.  Histidine permease is a multisubunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP.  HisP...; Region: ABC_HisP_GlnQ_permeases; cd03262
553482002821	Walker A/P-loop; other site
553482002822	ATP binding site [chemical binding]; other site
553482002823	Q-loop/lid; other site
553482002824	ABC transporter signature motif; other site
553482002825	Walker B; other site
553482002826	D-loop; other site
553482002827	H-loop/switch region; other site
553482002828	HMMPfam hit to PF00005, ABC transporter, score 5.8e-69
553482002829	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002830	PS00211 ABC transporters family signature.
553482002831	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
553482002832	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
553482002833	active site
553482002834	substrate binding site [chemical binding]; other site
553482002835	metal binding site [ion binding]; metal-binding site
553482002836	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 1.1e-56
553482002837	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482002838	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 0.017
553482002839	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 0.012
553482002840	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 0.029
553482002841	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14179
553482002842	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
553482002843	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
553482002844	homodimer interface [polypeptide binding]; other site
553482002845	NADP binding site [chemical binding]; other site
553482002846	substrate binding site [chemical binding]; other site
553482002847	HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohyd, score 1.2e-66
553482002848	PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
553482002849	HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohyd, score 9.8e-110
553482002850	PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
553482002851	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
553482002852	putative substrate binding site [chemical binding]; other site
553482002853	putative ATP binding site [chemical binding]; other site
553482002854	1 transmembrane helix predicted for SEQ0639 by TMHMM2.0 at aa 24-46
553482002855	HMMPfam hit to PF01256, Carbohydrate kinase, score 2.3e-66
553482002856	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002857	PS01050 Uncharacterized protein family UPF0031 signature 2.
553482002858	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
553482002859	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
553482002860	generic binding surface II; other site
553482002861	generic binding surface I; other site
553482002862	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.3e-14
553482002863	HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 8.5e-42
553482002864	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
553482002865	HMMPfam hit to PF02609, Exonuclease VII small subunit, score 1.1e-28
553482002866	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
553482002867	substrate binding pocket [chemical binding]; other site
553482002868	chain length determination region; other site
553482002869	substrate-Mg2+ binding site; other site
553482002870	catalytic residues [active]
553482002871	aspartate-rich region 1; other site
553482002872	active site lid residues [active]
553482002873	aspartate-rich region 2; other site
553482002874	HMMPfam hit to PF00348, Polyprenyl synthetase, score 1.9e-61
553482002875	PS00723 Polyprenyl synthetases signature 1.
553482002876	PS00444 Polyprenyl synthetases signature 2.
553482002877	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
553482002878	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
553482002879	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
553482002880	HMMPfam hit to PF01479, S4 domain, score 0.013
553482002881	HMMPfam hit to PF01728, FtsJ-like methyltransferase, score 0.00016
553482002882	Arginine repressor [Transcription]; Region: ArgR; COG1438
553482002883	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482002884	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 1.9e-24
553482002885	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 5.2e-19
553482002886	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
553482002887	RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and...; Region: ABC_RecN; cd03241
553482002888	Walker A/P-loop; other site
553482002889	ATP binding site [chemical binding]; other site
553482002890	Q-loop/lid; other site
553482002891	RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and...; Region: ABC_RecN; cd03241
553482002892	Q-loop/lid; other site
553482002893	ABC transporter signature motif; other site
553482002894	Walker B; other site
553482002895	D-loop; other site
553482002896	H-loop/switch region; other site
553482002897	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.8e-11
553482002898	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002899	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002900	Uncharacterized protein, DegV family COG1307; Region: DegV; cl00577
553482002901	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 3.6e-69
553482002902	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
553482002903	active site
553482002904	catalytic triad [active]
553482002905	oxyanion hole [active]
553482002906	1 transmembrane helix predicted for SEQ0648 by TMHMM2.0 at aa 5-27
553482002907	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 4.8e-22
553482002908	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; cl11548
553482002909	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
553482002910	IHF dimer interface [polypeptide binding]; other site
553482002911	IHF - DNA interface [nucleotide binding]; other site
553482002912	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1.1e-51
553482002913	PS00045 Bacterial histone-like DNA-binding proteins signature.
553482002914	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cd00233
553482002915	active site
553482002916	conformational flexibility of ligand binding pocket; other site
553482002917	ADP-ribosylating toxin turn-turn motif; other site
553482002918	HMMPfam hit to PF03496, Clostridial binary toxin A, score 5.6e-09
553482002919	1 transmembrane helix predicted for SEQ0651 by TMHMM2.0 at aa 15-32
553482002920	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482002921	Ferroportin1 (FPN1); Region: FPN1; pfam06963
553482002922	10 transmembrane helices predicted for SEQ0652 by TMHMM2.0 at aa 71-90, 94-116, 137-156, 160-182, 218-240, 255-274, 281-300, 304-326, 338-360 and 370-392
553482002923	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482002924	non-specific DNA binding site [nucleotide binding]; other site
553482002925	salt bridge; other site
553482002926	sequence-specific DNA binding site [nucleotide binding]; other site
553482002927	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482002928	HMMPfam hit to PF01381, Helix-turn-helix, score 2.9e-06
553482002929	1 transmembrane helix predicted for SEQ0654 by TMHMM2.0 at aa 4-24
553482002930	Dihydroorotate dehydrogenase [Nucleotide transport and metabolism]; Region: PyrD; COG0167
553482002931	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
553482002932	active site
553482002933	FMN binding site [chemical binding]; other site
553482002934	substrate binding site [chemical binding]; other site
553482002935	catalytic residues [active]
553482002936	homodimer interface [polypeptide binding]; other site
553482002937	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 9.9e-110
553482002938	PS00912 Dihydroorotate dehydrogenase signature 2.
553482002939	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002940	catalytic core [active]
553482002941	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002942	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.9e-44
553482002943	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
553482002944	Helix-turn-helix domains; Region: HTH; cl00088
553482002945	3H domain; Region: 3H; pfam02829
553482002946	HMMPfam hit to PF08279, HTH domain, score 1.2e-15
553482002947	Predicted helix-turn-helix motif with score 1167.000, SD 3.16 at aa 21-42, sequence ISATSLAKALGVSRQVIVGDIA
553482002948	HMMPfam hit to PF02829, 3H domain, score 2.8e-24
553482002949	5 transmembrane helices predicted for SEQ0658 by TMHMM2.0 at aa 10-32, 45-67, 72-94, 107-129 and 144-166
553482002950	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
553482002951	HMMPfam hit to PF01226, Formate/nitrite transporter, score 7.8e-39
553482002952	6 transmembrane helices predicted for SEQ0659 by TMHMM2.0 at aa 23-45, 60-82, 103-125, 156-178, 191-213 and 223-245
553482002953	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002954	PS01005 Formate and nitrite transporters signature 1.
553482002955	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002956	PS00213 Lipocalin signature.
553482002957	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
553482002958	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482002959	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482002960	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482002961	1 transmembrane helix predicted for SEQ0660 by TMHMM2.0 at aa 16-35
553482002962	HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 1.3e-37
553482002963	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 8.7e-86
553482002964	recombination protein RecR; Reviewed; Region: recR; PRK00076
553482002965	RecR protein; Region: RecR; pfam02132
553482002966	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
553482002967	putative active site [active]
553482002968	putative metal-binding site [ion binding]; other site
553482002969	tetramer interface [polypeptide binding]; other site
553482002970	HMMPfam hit to PF02132, RecR protein, score 7.6e-20
553482002971	PS01300 RecR protein signature.
553482002972	HMMPfam hit to PF01751, Toprim domain, score 3e-16
553482002973	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
553482002974	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
553482002975	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482002976	HMMPfam hit to PF01820, D-ala D-ala ligase N-terminus, score 3.6e-36
553482002977	PS00843 D-alanine--D-alanine ligase signature 1.
553482002978	HMMPfam hit to PF07478, D-ala D-ala ligase C-terminus, score 1.3e-94
553482002979	HMMPfam hit to PF02222, ATP-grasp domain, score 0.002
553482002980	PS00844 D-alanine--D-alanine ligase signature 2.
553482002981	putative transposase OrfB; Reviewed; Region: PHA02517
553482002982	HTH-like domain; Region: HTH_21; pfam13276
553482002983	Integrase core domain; Region: rve; cl01316
553482002984	Integrase core domain; Region: rve_3; cl15866
553482002985	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482002986	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482002987	Helix-turn-helix domains; Region: HTH; cl00088
553482002988	HMMPfam hit to PF01527, Transposase, score 0.00062
553482002989	HMMPfam hit to PF02178, no description, score 0.21
553482002990	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482002991	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
553482002992	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482002993	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482002994	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482002995	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 1.2e-11
553482002996	HMMPfam hit to PF08245, Mur ligase middle domain, score 9.4e-52
553482002997	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 5.2e-07
553482002998	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; cl02331
553482002999	5 transmembrane helices predicted for SEQ0668 by TMHMM2.0 at aa 11-33, 46-65, 121-143, 156-175 and 195-217
553482003000	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
553482003001	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
553482003002	G1 box; other site
553482003003	putative GEF interaction site [polypeptide binding]; other site
553482003004	GTP/Mg2+ binding site [chemical binding]; other site
553482003005	Switch I region; other site
553482003006	G2 box; other site
553482003007	G3 box; other site
553482003008	Switch II region; other site
553482003009	G4 box; other site
553482003010	G5 box; other site
553482003011	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
553482003012	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1e-66
553482003013	PS00301 GTP-binding elongation factors signature.
553482003014	HMMPfam hit to PF03144, Elongation factor Tu domain, score 4.5e-13
553482003015	PS00732 Ribosomal protein S16 signature.
553482003016	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
553482003017	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
553482003018	ATP binding site [chemical binding]; other site
553482003019	Mg++ binding site [ion binding]; other site
553482003020	motif III; other site
553482003021	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482003022	nucleotide binding region [chemical binding]; other site
553482003023	ATP-binding site [chemical binding]; other site
553482003024	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.5e-72
553482003025	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003026	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
553482003027	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.9e-35
553482003028	K+ potassium transporter; Region: K_trans; cl15781
553482003029	12 transmembrane helices predicted for SEQ0671 by TMHMM2.0 at aa 12-34, 54-76, 103-125, 140-162, 169-191, 220-242, 249-271, 291-313, 334-356, 371-393, 400-422 and 426-448
553482003030	HMMPfam hit to PF02705, K+ potassium transporter, score 1.4e-37
553482003031	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003032	putative transposase OrfB; Reviewed; Region: PHA02517
553482003033	HTH-like domain; Region: HTH_21; pfam13276
553482003034	Integrase core domain; Region: rve; cl01316
553482003035	Integrase core domain; Region: rve_3; cl15866
553482003036	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482003037	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003038	Helix-turn-helix domains; Region: HTH; cl00088
553482003039	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003040	HMMPfam hit to PF02178, no description, score 0.21
553482003041	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003042	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
553482003043	GIY-YIG motif/motif A; other site
553482003044	putative active site [active]
553482003045	putative metal binding site [ion binding]; other site
553482003046	HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 7e-23
553482003047	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
553482003048	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482003049	HMMPfam hit to PF05175, Methyltransferase small domain, score 5.3e-05
553482003050	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003051	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
553482003052	putative acyl-acceptor binding pocket; other site
553482003053	2 transmembrane helices predicted for SEQ0676 by TMHMM2.0 at aa 12-34 and 228-250
553482003054	HMMPfam hit to PF01553, Acyltransferase, score 3.9e-25
553482003055	SLBB domain; Region: SLBB; pfam10531
553482003056	comEA protein; Region: comE; TIGR01259
553482003057	1 transmembrane helix predicted for SEQ0677 by TMHMM2.0 at aa 17-39
553482003058	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
553482003059	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
553482003060	Competence protein; Region: Competence; cl00471
553482003061	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482003062	9 transmembrane helices predicted for SEQ0678 by TMHMM2.0 at aa 5-27, 32-51, 236-255, 270-292, 319-341, 370-392, 399-421, 436-458 and 465-487
553482003063	HMMPfam hit to PF03772, Competence protein, score 1.3e-38
553482003064	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
553482003065	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
553482003066	HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 2e-115
553482003067	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
553482003068	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
553482003069	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
553482003070	HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 2.2e-42
553482003071	HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 3e-61
553482003072	PS00088 Manganese and iron superoxide dismutases signature.
553482003073	Protein of unknown function (DUF3114); Region: DUF3114; pfam11311
553482003074	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
553482003075	Queuosine biosynthesis protein; Region: Queuosine_synth; cl00523
553482003076	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 6.3e-118
553482003077	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
553482003078	active site
553482003079	trimer interface [polypeptide binding]; other site
553482003080	allosteric site; other site
553482003081	active site lid [active]
553482003082	hexamer (dimer of trimers) interface [polypeptide binding]; other site
553482003083	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 6.8e-41
553482003084	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482003085	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
553482003086	PseudoU_synth_RsuA: Pseudouridine synthase, Escherichia coli RsuA like. This group is comprised of eukaryotic and bacterial proteins similar to Escherichia coli RsuA. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA...; Region: PseudoU_synth_RsuA; cd02553
553482003087	active site
553482003088	uracil binding [chemical binding]; other site
553482003089	HMMPfam hit to PF01479, S4 domain, score 2.5e-07
553482003090	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 7.2e-15
553482003091	PS01149 Rsu family of pseudouridine synthase signature.
553482003092	HMMPfam hit to PF06054, Competence protein CoiA-like family, score 4.7e-27
553482003093	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003094	Helix-turn-helix domains; Region: HTH; cl00088
553482003095	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003096	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003097	HMMPfam hit to PF02178, no description, score 0.21
553482003098	putative transposase OrfB; Reviewed; Region: PHA02517
553482003099	HTH-like domain; Region: HTH_21; pfam13276
553482003100	Integrase core domain; Region: rve; cl01316
553482003101	Integrase core domain; Region: rve_3; cl15866
553482003102	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003103	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
553482003104	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
553482003105	active site
553482003106	Zn binding site [ion binding]; other site
553482003107	HMMPfam hit to PF08439, Oligopeptidase F, score 1.2e-24
553482003108	HMMPfam hit to PF01432, Peptidase family M3, score 6e-148
553482003109	Predicted acetyltransferase [General function prediction only]; Region: COG3981
553482003110	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482003111	Coenzyme A binding pocket [chemical binding]; other site
553482003112	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.6e-10
553482003113	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
553482003114	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482003115	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003116	motif II; other site
553482003117	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.4e-22
553482003118	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
553482003119	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482003120	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003121	motif II; other site
553482003122	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.1e-25
553482003123	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
553482003124	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003125	S-adenosylmethionine binding site [chemical binding]; other site
553482003126	HMMPfam hit to PF01596, O-methyltransferase, score 6.8e-13
553482003127	HMMPfam hit to PF08241, Methyltransferase domain, score 6.2e-09
553482003128	HMMPfam hit to PF08242, Methyltransferase domain, score 6e-05
553482003129	foldase protein PrsA; Reviewed; Region: PRK12450
553482003130	SurA N-terminal domain; Region: SurA_N_3; cl07813
553482003131	PPIC-type PPIASE domain; Region: Rotamase; cl08278
553482003132	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003133	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
553482003134	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; Region: AlaRS_core; cd00673
553482003135	motif 1; other site
553482003136	active site
553482003137	motif 2; other site
553482003138	motif 3; other site
553482003139	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469
553482003140	DHHA1 domain; Region: DHHA1; pfam02272
553482003141	HMMPfam hit to PF01411, tRNA synthetases class II (A), score 5.3e-260
553482003142	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482003143	HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase seco, score 5.8e-23
553482003144	HMMPfam hit to PF02272, DHHA1 domain, score 4.8e-15
553482003145	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
553482003146	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 4.5e-31
553482003147	Catalytic NodB homology domain of Streptococcus pneumoniae peptidoglycan deacetylase PgdA, Bacillus subtilis BsYjeA protein, and their bacterial homologs; Region: CE4_SpPgdA_BsYjeA_like; cd10947
553482003148	NodB motif; other site
553482003149	active site
553482003150	catalytic site [active]
553482003151	Zn binding site [ion binding]; other site
553482003152	1 transmembrane helix predicted for SEQ0697 by TMHMM2.0 at aa 5-27
553482003153	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 2.8e-52
553482003154	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003155	ATP binding site [chemical binding]; other site
553482003156	putative Mg++ binding site [ion binding]; other site
553482003157	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482003158	nucleotide binding region [chemical binding]; other site
553482003159	ATP-binding site [chemical binding]; other site
553482003160	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.5e-25
553482003161	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.7e-36
553482003162	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
553482003163	Sugar specificity; other site
553482003164	Pyrimidine base specificity; other site
553482003165	ATP-binding site [chemical binding]; other site
553482003166	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 3.7e-54
553482003167	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003168	Protein of unknown function (DUF1294); Region: DUF1294; cl01311
553482003169	3 transmembrane helices predicted for SEQ0700 by TMHMM2.0 at aa 13-32, 47-69 and 76-98
553482003170	HMMPfam hit to PF06961, Protein of unknown function (DUF1294), score 7.6e-29
553482003171	Protease prsW family; Region: PrsW-protease; cl15823
553482003172	6 transmembrane helices predicted for SEQ0701 by TMHMM2.0 at aa 9-31, 41-63, 75-97, 117-139, 191-208 and 237-259
553482003173	GAF domain; Region: GAF; cl15785
553482003174	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
553482003175	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482003176	Walker A motif; other site
553482003177	ATP binding site [chemical binding]; other site
553482003178	Walker B motif; other site
553482003179	arginine finger; other site
553482003180	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
553482003181	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 9.3e-11
553482003182	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003183	Helix-turn-helix domains; Region: HTH; cl00088
553482003184	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
553482003185	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
553482003186	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
553482003187	HMMPfam hit to PF02237, Biotin protein ligase C terminal domain, score 1.7e-09
553482003188	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 0.0025
553482003189	HMMPfam hit to PF08279, HTH domain, score 4.4e-16
553482003190	Predicted helix-turn-helix motif with score 1186.000, SD 3.23 at aa 18-39, sequence VSGEYLAEQLKLSRTSVWKSIK
553482003191	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482003192	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482003193	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003194	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
553482003195	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
553482003196	Substrate binding site [chemical binding]; other site
553482003197	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003198	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.034
553482003199	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.00026
553482003200	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.016
553482003201	HMMPfam hit to PF00560, Leucine Rich Repeat, score 2
553482003202	HMMPfam hit to PF00560, Leucine Rich Repeat, score 7
553482003203	S-adenosylmethionine synthetase; Validated; Region: PRK05250
553482003204	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
553482003205	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
553482003206	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
553482003207	HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-te, score 2.4e-48
553482003208	HMMPfam hit to PF02772, S-adenosylmethionine synthetase, cent, score 1e-78
553482003209	PS00376 S-adenosylmethionine synthetase signature 1.
553482003210	HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-te, score 1.5e-82
553482003211	PS00377 S-adenosylmethionine synthetase signature 2.
553482003212	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
553482003213	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
553482003214	hinge; other site
553482003215	active site
553482003216	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 1.2e-100
553482003217	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003218	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003219	putative transposase OrfB; Reviewed; Region: PHA02517
553482003220	HTH-like domain; Region: HTH_21; pfam13276
553482003221	Integrase core domain; Region: rve; cl01316
553482003222	Integrase core domain; Region: rve_3; cl15866
553482003223	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003225	Helix-turn-helix domains; Region: HTH; cl00088
553482003226	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003227	HMMPfam hit to PF02178, no description, score 0.21
553482003228	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003229	MFS/sugar transport protein; Region: MFS_2; pfam13347
553482003230	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
553482003231	11 transmembrane helices predicted for SEQ0711 by TMHMM2.0 at aa 34-56, 91-113, 117-134, 155-177, 192-214, 255-277, 287-306, 313-335, 345-364, 404-426 and 441-463
553482003232	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
553482003233	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
553482003234	substrate binding site [chemical binding]; other site
553482003235	ATP binding site [chemical binding]; other site
553482003236	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 3.4e-16
553482003237	beta-D-glucuronidase; Provisional; Region: PRK10150
553482003238	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; cl08371
553482003239	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
553482003240	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl15381
553482003241	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.7e-42
553482003242	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 2.3e-12
553482003243	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 4.8e-93
553482003244	PS00719 Glycosyl hydrolases family 2 signature 1.
553482003245	Transcriptional regulators [Transcription]; Region: FadR; COG2186
553482003246	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003247	DNA-binding site [nucleotide binding]; DNA binding site
553482003248	FCD domain; Region: FCD; cl11656
553482003249	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.5e-18
553482003250	PS00043 Bacterial regulatory proteins, gntR family signature.
553482003251	Predicted helix-turn-helix motif with score 1121.000, SD 3.00 at aa 29-50, sequence PNEYELAQDLEVGRSTIREAVR
553482003252	HMMPfam hit to PF07729, FCD domain, score 2.4e-31
553482003253	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
553482003254	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
553482003255	active site
553482003256	intersubunit interface [polypeptide binding]; other site
553482003257	catalytic residue [active]
553482003258	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.9e-31
553482003259	Glucuronate isomerase; Region: UxaC; cl00829
553482003260	HMMPfam hit to PF02614, Glucuronate isomerase, score 1.2e-165
553482003261	mannonate dehydratase; Provisional; Region: PRK03906
553482003262	mannonate dehydratase; Region: uxuA; TIGR00695
553482003263	HMMPfam hit to PF03786, D-mannonate dehydratase (UxuA), score 9.7e-183
553482003264	putative D-mannonate oxidoreductase, classical (c) SDR; Region: mannonate_red_SDR_c; cd08935
553482003265	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
553482003266	putative NAD(P) binding site [chemical binding]; other site
553482003267	active site
553482003268	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.8e-10
553482003269	PS00061 Short-chain dehydrogenases/reductases family signature.
553482003270	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
553482003271	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00022
553482003272	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
553482003273	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
553482003274	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 7.8e-22
553482003275	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482003276	GA module; Region: GA; cl08325
553482003277	B domain; Region: IgG_binding_B; pfam01378
553482003278	B domain; Region: IgG_binding_B; pfam01378
553482003279	HMMPfam hit to PF01468, GA module, score 7.2e-17
553482003280	HMMPfam hit to PF01378, B domain, score 3.2e-29
553482003281	HMMPfam hit to PF01378, B domain, score 2.7e-34
553482003282	HMMPfam hit to PF00746, Gram positive anchor, score 1e-12
553482003283	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003284	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482003285	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482003286	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.9e-10
553482003287	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
553482003288	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003289	DNA-binding site [nucleotide binding]; DNA binding site
553482003290	DRTGG domain; Region: DRTGG; cl12147
553482003291	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
553482003292	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
553482003293	active site 2 [active]
553482003294	active site 1 [active]
553482003295	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 0.0045
553482003296	HMMPfam hit to PF08279, HTH domain, score 0.0038
553482003297	Predicted helix-turn-helix motif with score 1136.000, SD 3.06 at aa 20-41, sequence VSVRSISNHLKVSDGTAYRAIK
553482003298	HMMPfam hit to PF07085, DRTGG domain, score 2.1e-53
553482003299	HMMPfam hit to PF00571, CBS domain pair, score 1.7e-24
553482003300	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
553482003301	active site
553482003302	HMMPfam hit to PF00557, metallopeptidase family M24, score 2.8e-39
553482003303	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
553482003304	HMMPfam hit to PF03631, Ribonuclease BN-like family, score 2.4e-81
553482003305	5 transmembrane helices predicted for SEQ0725 by TMHMM2.0 at aa 35-57, 133-155, 183-205, 217-239 and 254-276
553482003306	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
553482003307	3-phosphoshikimate 1-carboxyvinyltransferase; Region: aroA; TIGR01356
553482003308	hinge; other site
553482003309	active site
553482003310	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 6.3e-137
553482003311	PS00104 EPSP synthase signature 1.
553482003312	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003313	shikimate kinase; Reviewed; Region: aroK; PRK00131
553482003314	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
553482003315	ADP binding site [chemical binding]; other site
553482003316	magnesium binding site [ion binding]; other site
553482003317	putative shikimate binding site; other site
553482003318	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003319	HMMPfam hit to PF01202, Shikimate kinase, score 7.6e-53
553482003320	PS01128 Shikimate kinase signature.
553482003321	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
553482003322	1 transmembrane helix predicted for SEQ0728 by TMHMM2.0 at aa 148-167
553482003323	HMMPfam hit to PF03816, Cell envelope-related transcriptional a, score 2.5e-79
553482003324	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
553482003325	TRAM domain; Region: TRAM; cl01282
553482003326	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
553482003327	HMMPfam hit to PF01938, TRAM domain, score 6e-09
553482003328	HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 8.8e-07
553482003329	ICESe1
553482003330	Helix-turn-helix domains; Region: HTH; cl00088
553482003331	HMMPfam hit to PF06970, Replication initiator protein A (RepA) N-ter, score 6.6e-37
553482003332	hypothetical protein; Validated; Region: PRK08116
553482003333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482003334	Walker A motif; other site
553482003335	ATP binding site [chemical binding]; other site
553482003336	Walker B motif; other site
553482003337	PS00190 Cytochrome c family heme-binding site signature.
553482003338	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003339	Protein of unknown function (DUF3801); Region: DUF3801; pfam12687
553482003340	CDS contains a frameshifts after codons 94 and 480
553482003341	2 transmembrane helices predicted for SEQ0733 by TMHMM2.0 at aa 21-43 and 69-91
553482003342	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003343	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
553482003344	generic binding surface II; other site
553482003345	generic binding surface I; other site
553482003346	Maff2 family; Region: Maff2; pfam12750
553482003347	2 transmembrane helices predicted for SEQ0737 by TMHMM2.0 at aa 7-28 and 48-70
553482003348	CDS contains a nonsense mutation (opal) after codon 107. Similar to Clostridium difficile membrane protein UniProt:Q188K5 (EMBL:AM180355 (287 aa) fasta scores: E()=3.2e-96, 96.875% id in 288 aa
553482003349	1 transmembrane helix predicted for SEQ0738 by TMHMM2.0 at aa 64-86
553482003350	3 transmembrane helices predicted for SEQ0739 by TMHMM2.0 at aa 56-78, 114-136 and 151-173
553482003351	1 transmembrane helix predicted for SEQ0740 by TMHMM2.0 at aa 7-24
553482003352	PrgI family protein; Region: PrgI; pfam12666
553482003353	2 transmembrane helices predicted for SEQ0741 by TMHMM2.0 at aa 21-43 and 47-69
553482003354	AAA-like domain; Region: AAA_10; pfam12846
553482003355	Domain of unknown function DUF87; Region: DUF87; pfam01935
553482003356	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003357	Predicted helix-turn-helix motif with score 1329.000, SD 3.71 at aa 653-674, sequence GDREILARKLKISLPQLRYVTN
553482003358	NlpC/P60 family; Region: NLPC_P60; cl11438
553482003359	1 transmembrane helix predicted for SEQ0743 by TMHMM2.0 at aa 360-382
553482003360	Domain of unknown function (DUF4366); Region: DUF4366; pfam14283
553482003361	2 transmembrane helices predicted for SEQ0745 by TMHMM2.0 at aa 12-34 and 452-474
553482003362	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003363	CDS is truncated by the insertion of the downstream IS element and subsequent deletion events. Similar to N-terminal region of Clostridium difficile DNA topoisomerase UniProt:Q188K6 (EMBL:AM180355 (568 aa) fasta scores: E()=3.4e-86, 89.734% id in 263 aa
553482003364	HMMPfam hit to PF01751, Toprim domain, score 3e-21
553482003365	putative transposase OrfB; Reviewed; Region: PHA02517
553482003366	HTH-like domain; Region: HTH_21; pfam13276
553482003367	Integrase core domain; Region: rve; cl01316
553482003368	Integrase core domain; Region: rve_3; cl15866
553482003369	HMMPfam hit to PF00665, Integrase core domain, score 3.6e-35
553482003370	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003371	Helix-turn-helix domains; Region: HTH; cl00088
553482003372	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003373	HMMPfam hit to PF02178, no description, score 0.21
553482003374	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003375	CDS is truncated by the insertion of the upstream IS element and subsequent deletion events. Similar to Clostridium difficile DNA topoisomerase UniProt:Q188K6 (EMBL:AM180355 (568 aa) fasta scores: E()=1.8e-23, 89.655% id in 87 aa
553482003376	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
553482003377	HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 2.8e-07
553482003378	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
553482003379	Divergent AAA domain; Region: AAA_4; pfam04326
553482003380	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
553482003381	Helix-turn-helix domains; Region: HTH; cl00088
553482003382	non-specific DNA interactions [nucleotide binding]; other site
553482003383	DNA binding site [nucleotide binding]
553482003384	sequence specific DNA binding site [nucleotide binding]; other site
553482003385	putative cAMP binding site [chemical binding]; other site
553482003386	HMMPfam hit to PF04326, Divergent AAA domain, score 4e-21
553482003387	Predicted helix-turn-helix motif with score 1981.000, SD 5.93 at aa 434-455, sequence ITRKAIADEAGVSVKTIERAIK
553482003388	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003389	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
553482003390	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
553482003391	putative active site [active]
553482003392	putative NTP binding site [chemical binding]; other site
553482003393	putative nucleic acid binding site [nucleotide binding]; other site
553482003394	Type II intron maturase; Region: Intron_maturas2; pfam01348
553482003395	HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent, score 2.2e-73
553482003396	HMMPfam hit to PF01348, Type II intron maturase, score 1.5e-06
553482003397	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.00019
553482003398	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482003399	Predicted helix-turn-helix motif with score 1355.000, SD 3.80 at aa 24-45, sequence MKNSELMEKAEVSRSTFYKMKN
553482003400	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
553482003401	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003402	S-adenosylmethionine binding site [chemical binding]; other site
553482003403	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482003404	HMMPfam hit to PF07669, Eco57I restriction endonuclease, score 6.4e-06
553482003405	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003406	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
553482003407	HMMPfam hit to PF06616, BsuBI/PstI restriction endonuclease C-t, score 2.7e-89
553482003408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003409	Helix-turn-helix domains; Region: HTH; cl00088
553482003410	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003411	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003412	HMMPfam hit to PF02178, no description, score 0.21
553482003413	putative transposase OrfB; Reviewed; Region: PHA02517
553482003414	HTH-like domain; Region: HTH_21; pfam13276
553482003415	Integrase core domain; Region: rve; cl01316
553482003416	Integrase core domain; Region: rve_3; cl15866
553482003417	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003418	Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIR2-like; cd01406
553482003419	TIR domain; Region: TIR_2; cl15770
553482003420	gene remnant. Similar to the C-terminal region of Clostridium difficile 630 mobilization protein UniProt:Q188L0 (EMBL:AM180355 (443 aa) fasta scores: E()=4.6e-32, 87.879% id in 132 aa
553482003421	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
553482003422	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003423	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003424	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482003425	catalytic core [active]
553482003426	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.5e-39
553482003427	hypothetical protein; Provisional; Region: PRK11770
553482003428	Domain of unknown function (DUF307); Region: DUF307; pfam03733
553482003429	Domain of unknown function (DUF307); Region: DUF307; pfam03733
553482003430	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 3.6e-21
553482003431	3 transmembrane helices predicted for SEQ0766 by TMHMM2.0 at aa 15-37, 50-72 and 77-99
553482003432	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 1.9e-13
553482003433	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
553482003434	putative deacylase active site [active]
553482003435	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 1.2e-54
553482003436	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl01942
553482003437	5 transmembrane helices predicted for SEQ0768 by TMHMM2.0 at aa 13-35, 50-69, 74-96, 111-133 and 154-176
553482003438	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
553482003439	PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis.  PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b.  Both domains are required for...; Region: GH25_PlyB-like; cd06523
553482003440	active site
553482003441	HMMPfam hit to PF01183, Glycosyl hydrolases family, score 2e-06
553482003442	1 transmembrane helix predicted for SEQ0769 by TMHMM2.0 at aa 7-24
553482003443	5 transmembrane helices predicted for SEQ0770 by TMHMM2.0 at aa 10-29, 36-58, 68-90, 103-125 and 135-157
553482003444	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003445	10 transmembrane helices predicted for SEQ0771 by TMHMM2.0 at aa 21-43, 48-70, 77-99, 103-121, 165-187, 242-264, 285-307, 311-328, 341-363 and 368-390
553482003446	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
553482003447	catalytic residues [active]
553482003448	dimer interface [polypeptide binding]; other site
553482003449	HMMPfam hit to PF00255, Glutathione peroxidase, score 3e-50
553482003450	PS00763 Glutathione peroxidases signature 2.
553482003451	PS00460 Glutathione peroxidases selenocysteine active site.
553482003452	CDS contains a frameshift after codon 126. Frameshift occurs at a poly A octamer
553482003453	HMMPfam hit to PF01432, Peptidase family M3, score 1.2e-33
553482003454	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482003455	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl14656
553482003456	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
553482003457	HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase, score 1.6e-86
553482003458	PS00781 Phosphoenolpyruvate carboxylase active site 1.
553482003459	PS00393 Phosphoenolpyruvate carboxylase active site 2.
553482003460	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
553482003461	HMMPfam hit to PF01098, Cell cycle protein, score 2.4e-91
553482003462	8 transmembrane helices predicted for SEQ0777 by TMHMM2.0 at aa 13-35, 50-72, 77-99, 179-198, 203-225, 302-324, 337-359 and 364-386
553482003463	putative transposase OrfB; Reviewed; Region: PHA02517
553482003464	HTH-like domain; Region: HTH_21; pfam13276
553482003465	Integrase core domain; Region: rve; cl01316
553482003466	Integrase core domain; Region: rve_3; cl15866
553482003467	HMMPfam hit to PF00665, Integrase core domain, score 1.8e-39
553482003468	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003469	Helix-turn-helix domains; Region: HTH; cl00088
553482003470	HMMPfam hit to PF01527, Transposase, score 0.0014
553482003471	HMMPfam hit to PF02178, no description, score 0.21
553482003472	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003473	gene remnant. Similar to the C-terminal region of Streptococcus thermophilus peptide-2 ABC exporter family, ATP binding/membrane-spannin protein UniProt:Q5M3B9 (EMBL:CP000023 (523 aa) fasta scores: E()=9.4e-18, 42.246% id in 187 aa
553482003474	HMMPfam hit to PF00005, ABC transporter, score 6.1e-35
553482003475	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003476	PS00211 ABC transporters family signature.
553482003477	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482003478	The MRP (Mutidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export.  They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins.  The ABCC subfamily contains transporters with a...; Region: ABCC_MRP_Like; cd03228
553482003479	Walker A/P-loop; other site
553482003480	ATP binding site [chemical binding]; other site
553482003481	Q-loop/lid; other site
553482003482	ABC transporter signature motif; other site
553482003483	Walker B; other site
553482003484	D-loop; other site
553482003485	H-loop/switch region; other site
553482003486	5 transmembrane helices predicted for SEQ0781 by TMHMM2.0 at aa 7-29, 52-74, 115-137, 147-166 and 231-253
553482003487	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003488	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003489	HMMPfam hit to PF00005, ABC transporter, score 3.6e-32
553482003490	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003491	PS00211 ABC transporters family signature.
553482003492	peptide chain release factor 2; Validated; Region: prfB; PRK00578
553482003493	RF-1 domain; Region: RF-1; cl02875
553482003494	RF-1 domain; Region: RF-1; cl02875
553482003495	HMMPfam hit to PF03462, PCRF domain, score 2.4e-58
553482003496	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 1.3e-64
553482003497	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
553482003498	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003499	Walker A/P-loop; other site
553482003500	ATP binding site [chemical binding]; other site
553482003501	Q-loop/lid; other site
553482003502	ABC transporter signature motif; other site
553482003503	Walker B; other site
553482003504	D-loop; other site
553482003505	H-loop/switch region; other site
553482003506	HMMPfam hit to PF00005, ABC transporter, score 3.4e-61
553482003507	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003508	PS00211 ABC transporters family signature.
553482003509	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
553482003510	FtsX-like permease family; Region: FtsX; cl15850
553482003511	4 transmembrane helices predicted for SEQ0784 by TMHMM2.0 at aa 23-45, 183-205, 235-257 and 282-304
553482003512	HMMPfam hit to PF02687, Predicted permease, score 3.5e-34
553482003513	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482003514	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK07246
553482003515	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482003516	active site
553482003517	catalytic site [active]
553482003518	substrate binding site [chemical binding]; other site
553482003519	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003520	ATP binding site [chemical binding]; other site
553482003521	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003522	HMMPfam hit to PF00929, Exonuclease, score 2.8e-35
553482003523	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003524	prophage phiSeq2
553482003525	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
553482003526	DNA binding site [nucleotide binding]
553482003527	Int/Topo IB signature motif; other site
553482003528	active site
553482003529	catalytic residues [active]
553482003530	HMMPfam hit to PF00589, Phage integrase family, score 1e-06
553482003531	ORF059 IMV protein VP55; Provisional; Region: PHA02688
553482003532	2 transmembrane helices predicted for SEQ0788 by TMHMM2.0 at aa 36-58 and 62-84
553482003533	Domain of unknown function (DUF955); Region: DUF955; cl01076
553482003534	HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 1.1e-20
553482003535	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482003536	non-specific DNA binding site [nucleotide binding]; other site
553482003537	salt bridge; other site
553482003538	sequence-specific DNA binding site [nucleotide binding]; other site
553482003539	HMMPfam hit to PF01381, Helix-turn-helix, score 9.5e-11
553482003540	Predicted helix-turn-helix motif with score 1486.000, SD 4.25 at aa 17-38, sequence ISIAKLEENLGLSKNAIYAIKR
553482003541	putative transposase OrfB; Reviewed; Region: PHA02517
553482003542	HTH-like domain; Region: HTH_21; pfam13276
553482003543	Integrase core domain; Region: rve; cl01316
553482003544	Integrase core domain; Region: rve_3; cl15866
553482003545	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003546	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003547	Helix-turn-helix domains; Region: HTH; cl00088
553482003548	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003549	HMMPfam hit to PF02178, no description, score 0.21
553482003550	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003551	HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 0.015
553482003552	Predicted helix-turn-helix motif with score 1749.000, SD 5.14 at aa 36-57, sequence LTREKVADRLNMSPATFDKYYR
553482003553	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
553482003554	HMMPfam hit to PF05565, Siphovirus Gp157, score 1.3e-48
553482003555	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482003556	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 4.3e-06
553482003557	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003558	ERF superfamily; Region: ERF; pfam04404
553482003559	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
553482003560	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482003561	dimer interface [polypeptide binding]; other site
553482003562	ssDNA binding site [nucleotide binding]; other site
553482003563	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482003564	HMMPfam hit to PF00436, Single-strand binding protein family, score 9.7e-32
553482003565	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
553482003566	polymerase nucleotide-binding site; other site
553482003567	DNA-binding residues [nucleotide binding]; DNA binding site
553482003568	nucleotide binding site [chemical binding]; other site
553482003569	primase nucleotide-binding site [nucleotide binding]; other site
553482003570	Primase C terminal 1 (PriCT-1); Region: PriCT_1; cl07362
553482003571	Virulence-associated protein E; Region: VirE; pfam05272
553482003572	HMMPfam hit to PF05272, Virulence-associated protein E, score 1.3e-77
553482003573	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003574	1 transmembrane helix predicted for SEQ0806 by TMHMM2.0 at aa 7-26
553482003575	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003576	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482003577	HMMPfam hit to PF01555, DNA methylase, score 2e-51
553482003578	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003579	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003580	CDS contains a frameshift after codon 263. Similar to Streptococcus pyogenes serotype M6 DNA-cytosine methyltransferase UniProt:Q5XBD5 (EMBL:CP000003 (422 aa) fasta scores: E()=2.1e-31, 31.860% id in 430 aa
553482003581	HMMPfam hit to PF00145, C-5 cytosine-specific DNA methylase, score 4.3e-54
553482003582	PS00094 C-5 cytosine-specific DNA methylases active site.
553482003583	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482003584	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482003585	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 8.8e-25
553482003586	3 transmembrane helices predicted for SEQ0811 by TMHMM2.0 at aa 24-46, 56-75 and 88-107
553482003587	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
553482003588	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
553482003589	HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 1.7e-18
553482003590	YcfA-like protein; Region: YcfA; cl00752
553482003591	HMMPfam hit to PF07927, YcfA-like protein, score 1.2e-20
553482003592	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
553482003593	HMMPfam hit to PF01844, HNH endonuclease, score 2.4e-06
553482003594	Phage terminase, small subunit; Region: Terminase_4; cl01525
553482003595	HMMPfam hit to PF05119, Phage terminase, small subunit, score 4.7e-21
553482003596	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
553482003597	Phage Terminase; Region: Terminase_1; pfam03354
553482003598	HMMPfam hit to PF03354, Phage Terminase, score 1.2e-121
553482003599	2 transmembrane helices predicted for SEQ0821 by TMHMM2.0 at aa 5-27 and 32-51
553482003600	Phage portal protein; Region: Phage_portal; pfam04860
553482003601	Phage-related protein [Function unknown]; Region: COG4695; cl01923
553482003602	HMMPfam hit to PF04860, Phage portal protein, score 5.1e-35
553482003603	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
553482003604	oligomer interface [polypeptide binding]; other site
553482003605	active site residues [active]
553482003606	HMMPfam hit to PF00574, Clp protease, score 1.7e-24
553482003607	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
553482003608	Phage capsid family; Region: Phage_capsid; pfam05065
553482003609	HMMPfam hit to PF05065, Phage capsid family, score 2.4e-111
553482003610	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003611	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
553482003612	oligomerization interface [polypeptide binding]; other site
553482003613	Phage head-tail joining protein; Region: Phage_H_T_join; cl11461
553482003614	Bacteriophage protein of unknown function (DUF646); Region: DUF646; cl12124
553482003615	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
553482003616	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
553482003617	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
553482003618	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482003619	Predicted helix-turn-helix motif with score 1118.000, SD 2.99 at aa 685-706, sequence KKDLKLAEKLGLSQETIEEIRR
553482003620	Phage-related protein [Function unknown]; Region: COG4722; cl15832
553482003621	Phage tail protein; Region: Sipho_tail; pfam05709
553482003622	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482003623	ATP-dependent protease La; Region: lon; TIGR00763
553482003624	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003625	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 6.5e-06
553482003626	gp58-like protein; Region: Gp58; pfam07902
553482003627	HMMPfam hit to PF07902, gp58-like protein, score 0
553482003628	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482003629	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 3e-95
553482003630	1 transmembrane helix predicted for SEQ0842 by TMHMM2.0 at aa 4-26
553482003631	1 transmembrane helix predicted for SEQ0843 by TMHMM2.0 at aa 21-43
553482003632	1 transmembrane helix predicted for SEQ0844 by TMHMM2.0 at aa 7-29
553482003633	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482003634	NlpC/P60 family; Region: NLPC_P60; cl11438
553482003635	Bacterial SH3 domain; Region: SH3_3; cl02551
553482003636	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 6.3e-18
553482003637	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482003638	HMMPfam hit to PF05257, CHAP domain, score 1.2e-32
553482003639	HMMPfam hit to PF08460, Bacterial SH3 domain, score 2.3e-07
553482003640	Protein of unknown function (DUF4065); Region: DUF4065; cl01445
553482003641	3 transmembrane helices predicted for SEQ0847 by TMHMM2.0 at aa 167-189, 204-226 and 258-277
553482003642	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; cl09771
553482003643	PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; Region: PLA2_like; cl05417
553482003644	primary metal binding site; other site
553482003645	catalytic residues [active]
553482003646	1 transmembrane helix predicted for SEQ0849 by TMHMM2.0 at aa 5-27
553482003647	3 transmembrane helices predicted for SEQ0850 by TMHMM2.0 at aa 12-29, 39-61 and 68-90
553482003648	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
553482003649	aspartate aminotransferase; Provisional; Region: PRK05764
553482003650	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482003651	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482003652	homodimer interface [polypeptide binding]; other site
553482003653	catalytic residue [active]
553482003654	HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.7e-94
553482003655	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
553482003656	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
553482003657	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
553482003658	putative dimer interface [polypeptide binding]; other site
553482003659	putative anticodon binding site; other site
553482003660	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
553482003661	homodimer interface [polypeptide binding]; other site
553482003662	motif 1; other site
553482003663	motif 2; other site
553482003664	active site
553482003665	motif 3; other site
553482003666	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.5e-17
553482003667	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 1.5e-96
553482003668	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482003669	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482003670	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003671	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003672	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003673	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.4e-11
553482003674	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.6e-14
553482003675	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1e-13
553482003676	HMMPfam hit to PF00746, Gram positive anchor, score 1.1e-06
553482003677	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003678	1 transmembrane helix predicted for SEQ0855 by TMHMM2.0 at aa 342-359
553482003679	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
553482003680	Predicted P-loop-containing kinase [General function prediction only]; Region: COG1660
553482003681	HMMPfam hit to PF03668, P-loop ATPase protein family, score 9.1e-126
553482003682	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003683	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003684	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cd07044
553482003685	Uncharacterized protein family UPF0052; Region: UPF0052; pfam01933
553482003686	dimer interface [polypeptide binding]; other site
553482003687	phosphate binding site [ion binding]; other site
553482003688	HMMPfam hit to PF01933, Uncharacterised protein family UPF0052, score 4.9e-146
553482003689	PS01036 Heat shock hsp70 proteins family signature 3.
553482003690	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
553482003691	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
553482003692	HMMPfam hit to PF02650, Uncharacterized BCR, COG1481, score 1.5e-64
553482003693	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
553482003694	Peptidase family C69; Region: Peptidase_C69; pfam03577
553482003695	HMMPfam hit to PF03577, Peptidase family C69, score 1.1e-273
553482003696	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
553482003697	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
553482003698	metal binding site [ion binding]; metal-binding site
553482003699	YodA lipocalin-like domain; Region: YodA; cl01365
553482003700	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 3.4e-82
553482003701	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482003702	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003703	DNA-binding site [nucleotide binding]; DNA binding site
553482003704	UTRA domain; Region: UTRA; cl01230
553482003705	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-14
553482003706	PS00043 Bacterial regulatory proteins, gntR family signature.
553482003707	Predicted helix-turn-helix motif with score 1586.000, SD 4.59 at aa 30-51, sequence LSERELSDLFGVSRITIRLALK
553482003708	HMMPfam hit to PF07702, UTRA domain, score 1.5e-43
553482003709	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
553482003710	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
553482003711	dimer interface [polypeptide binding]; other site
553482003712	active site
553482003713	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
553482003714	putative active site [active]
553482003715	HMMPfam hit to PF01380, SIS domain, score 5e-06
553482003716	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003717	HMMPfam hit to PF01380, SIS domain, score 0.022
553482003718	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
553482003719	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 3e-103
553482003720	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482003721	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003722	DNA-binding site [nucleotide binding]; DNA binding site
553482003723	UTRA domain; Region: UTRA; cl01230
553482003724	HMMPfam hit to PF07702, UTRA domain, score 6.6e-05
553482003725	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 6.9e-13
553482003726	Predicted helix-turn-helix motif with score 1112.000, SD 2.97 at aa 31-52, sequence YTEAELIKRFHVSSITIIRALK
553482003727	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 1.2e-170
553482003728	HMMPfam hit to PF02449, Beta-galactosidase, score 0.00023
553482003729	putative transposase OrfB; Reviewed; Region: PHA02517
553482003730	HTH-like domain; Region: HTH_21; pfam13276
553482003731	Integrase core domain; Region: rve; cl01316
553482003732	Integrase core domain; Region: rve_3; cl15866
553482003733	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003734	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003735	Helix-turn-helix domains; Region: HTH; cl00088
553482003736	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003737	HMMPfam hit to PF02178, no description, score 0.21
553482003738	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003739	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482003740	active site
553482003741	phosphorylation site [posttranslational modification]
553482003742	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 1.3e-66
553482003743	CDS contains a nonsense mutation (ochre) after codon 139. Similar to Streptococcus pneumoniae R6 Phosphotransferase system sugar-specific EIIC component PTS-EIIC UniProt:Q8DRL2 (EMBL:AE008390 (301 aa) fasta scores: E()=3.9e-61, 69.435% id in 301 aa
553482003744	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1.9e-17
553482003745	6 transmembrane helices predicted for SEQ0871 by TMHMM2.0 at aa 21-43, 47-69, 143-165, 175-197, 204-226 and 241-263
553482003746	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
553482003747	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 1.4e-103
553482003748	5 transmembrane helices predicted for SEQ0872 by TMHMM2.0 at aa 115-132, 136-158, 179-201, 225-244 and 253-270
553482003749	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482003750	active pocket/dimerization site; other site
553482003751	active site
553482003752	phosphorylation site [posttranslational modification]
553482003753	HMMPfam hit to PF03610, PTS system fructose IIA component, score 1.1e-26
553482003754	Ribosomal protein L31; Region: Ribosomal_L31; cl00377
553482003755	HMMPfam hit to PF01197, Ribosomal protein L31, score 2.4e-21
553482003756	PS01143 Ribosomal protein L31 signature.
553482003757	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
553482003758	DHH family; Region: DHH; pfam01368
553482003759	DHHA1 domain; Region: DHHA1; pfam02272
553482003760	HMMPfam hit to PF02272, DHHA1 domain, score 3.6e-06
553482003761	HMMPfam hit to PF01368, DHH family, score 5.6e-43
553482003762	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482003763	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.2e-09
553482003764	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
553482003765	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482003766	active site
553482003767	HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 2.6e-54
553482003768	HMMPfam hit to PF02828, L27 domain, score 0.035
553482003769	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
553482003770	HMMPfam hit to PF00258, Flavodoxin, score 1.6e-28
553482003771	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 0.00041
553482003772	PS00201 Flavodoxin signature.
553482003773	Chorismate mutase type II; Region: CM_2; cl00693
553482003774	HMMPfam hit to PF01817, Chorismate mutase type II, score 9.7e-24
553482003775	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
553482003776	Voltage gated chloride channel; Region: Voltage_CLC; pfam00654
553482003777	Cl- selectivity filter; other site
553482003778	Cl- binding residues [ion binding]; other site
553482003779	pore gating glutamate residue; other site
553482003780	dimer interface [polypeptide binding]; other site
553482003781	10 transmembrane helices predicted for SEQ0880 by TMHMM2.0 at aa 17-36, 51-73, 94-111, 146-168, 173-195, 215-237, 256-278, 320-339, 346-368 and 372-391
553482003782	HMMPfam hit to PF00654, Voltage gated chloride channel, score 5e-11
553482003783	Ribosomal protein L19; Region: Ribosomal_L19; cl00406
553482003784	PS01015 Ribosomal protein L19 signature.
553482003785	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482003786	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
553482003787	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 2.1e-05
553482003788	1 transmembrane helix predicted for SEQ0882 by TMHMM2.0 at aa 25-42
553482003789	Predicted helix-turn-helix motif with score 975.000, SD 2.51 at aa 4-25, sequence LTRKQKKEGIDMSKSRRRNWKS
553482003790	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482003791	non-specific DNA binding site [nucleotide binding]; other site
553482003792	salt bridge; other site
553482003793	sequence-specific DNA binding site [nucleotide binding]; other site
553482003794	HMMPfam hit to PF01381, Helix-turn-helix, score 7e-15
553482003795	Predicted helix-turn-helix motif with score 1899.000, SD 5.65 at aa 18-39, sequence INQTQMAALAGVSRQTISLIER
553482003796	Protein of unknown function (DUF3169); Region: DUF3169; pfam11368
553482003797	6 transmembrane helices predicted for SEQ0884 by TMHMM2.0 at aa 20-42, 62-81, 108-130, 140-162, 204-226 and 230-247
553482003798	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
553482003799	putative ion selectivity filter; other site
553482003800	Voltage gated chloride channel; Region: Voltage_CLC; pfam00654
553482003801	putative pore gating glutamate residue; other site
553482003802	11 transmembrane helices predicted for SEQ0885 by TMHMM2.0 at aa 7-29, 33-55, 62-79, 157-179, 186-208, 223-245, 258-280, 295-317, 324-346, 356-378 and 385-407
553482003803	HMMPfam hit to PF00654, Voltage gated chloride channel, score 2.3e-07
553482003804	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
553482003805	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
553482003806	dimer interface [polypeptide binding]; other site
553482003807	putative radical transfer pathway; other site
553482003808	diiron center [ion binding]; other site
553482003809	tyrosyl radical; other site
553482003810	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 1.7e-61
553482003811	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
553482003812	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
553482003813	Class I ribonucleotide reductase; Region: RNR_I; cd01679
553482003814	active site
553482003815	dimer interface [polypeptide binding]; other site
553482003816	catalytic residues [active]
553482003817	effector binding site; other site
553482003818	R2 peptide binding site; other site
553482003819	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 5.3e-130
553482003820	PS00089 Ribonucleotide reductase large subunit signature.
553482003821	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 1.2e-26
553482003822	HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 2.2e-42
553482003823	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
553482003824	catalytic residues [active]
553482003825	HMMPfam hit to PF00462, Glutaredoxin, score 9.6e-16
553482003826	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
553482003827	dimerization domain swap beta strand [polypeptide binding]; other site
553482003828	regulatory protein interface [polypeptide binding]; other site
553482003829	active site
553482003830	regulatory phosphorylation site [posttranslational modification]; other site
553482003831	HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 5.5e-52
553482003832	PS00369 PTS HPR component histidine phosphorylation site signature.
553482003833	PS00589 PTS HPR component serine phosphorylation site signature.
553482003834	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
553482003835	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
553482003836	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; cl01586
553482003837	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl09155
553482003838	HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 1.4e-59
553482003839	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 1.7e-40
553482003840	PS00370 PEP-utilizing enzymes phosphorylation site signature.
553482003841	HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 1.1e-193
553482003842	PS00742 PEP-utilizing enzymes signature 2.
553482003843	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
553482003844	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
553482003845	tetrameric interface [polypeptide binding]; other site
553482003846	activator binding site; other site
553482003847	NADP binding site [chemical binding]; other site
553482003848	substrate binding site [chemical binding]; other site
553482003849	catalytic residues [active]
553482003850	HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7.9e-180
553482003851	PS00070 Aldehyde dehydrogenases cysteine active site.
553482003852	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
553482003853	10 transmembrane helices predicted for SEQ0892 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 115-137, 150-169, 173-192, 194-216, 288-310, 323-345 and 360-382
553482003854	HMMPfam hit to PF01098, Cell cycle protein, score 9.2e-70
553482003855	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
553482003856	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003857	motif II; other site
553482003858	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.5e-14
553482003859	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
553482003860	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482003861	Mg2+ binding site [ion binding]; other site
553482003862	G-X-G motif; other site
553482003863	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
553482003864	anchoring element; other site
553482003865	dimer interface [polypeptide binding]; other site
553482003866	ATP binding site [chemical binding]; other site
553482003867	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
553482003868	active site
553482003869	putative metal-binding site [ion binding]; other site
553482003870	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
553482003871	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 7.1e-27
553482003872	HMMPfam hit to PF00204, DNA gyrase B, score 1.4e-92
553482003873	HMMPfam hit to PF01751, Toprim domain, score 3.9e-09
553482003874	PS00177 DNA topoisomerase II signature.
553482003875	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 1.2e-46
553482003876	septation ring formation regulator EzrA; Provisional; Region: PRK04778
553482003877	1 transmembrane helix predicted for SEQ0895 by TMHMM2.0 at aa 5-27
553482003878	HMMPfam hit to PF06160, Septation ring formation regulator, EzrA, score 0
553482003879	Protein of unknown function (DUF1694); Region: DUF1694; cl02318
553482003880	HMMPfam hit to PF07997, Protein of unknown function (DUF1694), score 6.8e-39
553482003881	enolase; Provisional; Region: eno; PRK00077
553482003882	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
553482003883	dimer interface [polypeptide binding]; other site
553482003884	metal binding site [ion binding]; metal-binding site
553482003885	substrate binding pocket [chemical binding]; other site
553482003886	HMMPfam hit to PF03952, Enolase, N-terminal domain, score 2e-68
553482003887	HMMPfam hit to PF00113, Enolase, C-terminal TIM barrel domain, score 1.3e-164
553482003888	PS00164 Enolase signature.
553482003890	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl11422
553482003891	HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 2.3e-15
553482003892	HAD superfamily (subfamily IA) hydrolase, TIGR02253; Region: CTE7
553482003893	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003894	motif II; other site
553482003895	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0007
553482003896	Predicted extracellular nuclease [General function prediction only]; Region: COG2374
553482003897	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
553482003898	generic binding surface II; other site
553482003899	generic binding surface I; other site
553482003900	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
553482003901	generic binding surface I; other site
553482003902	generic binding surface II; other site
553482003903	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
553482003904	putative catalytic site [active]
553482003905	putative metal binding site [ion binding]; other site
553482003906	putative phosphate binding site [ion binding]; other site
553482003907	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3e-17
553482003908	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003909	1 transmembrane helix predicted for SEQ0904 by TMHMM2.0 at aa 900-919
553482003910	QueT transporter; Region: QueT; cl01932
553482003911	HMMPfam hit to PF06177, Protein of unknown function (DUF988), score 6.4e-97
553482003912	5 transmembrane helices predicted for SEQ0905 by TMHMM2.0 at aa 10-32, 45-67, 71-93, 109-131 and 135-157
553482003913	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
553482003914	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
553482003915	nucleotide binding pocket [chemical binding]; other site
553482003916	K-X-D-G motif; other site
553482003917	catalytic site [active]
553482003918	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
553482003919	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
553482003920	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
553482003921	Dimer interface [polypeptide binding]; other site
553482003922	BRCT sequence motif; other site
553482003923	HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 6.3e-153
553482003924	PS01055 NAD-dependent DNA ligase signature 1.
553482003925	HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 3e-46
553482003926	PS01056 NAD-dependent DNA ligase signature 2.
553482003927	HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc fing, score 5.1e-13
553482003928	HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain, score 8.4e-15
553482003929	putative lipid kinase; Reviewed; Region: PRK13055
553482003930	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255
553482003931	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255
553482003932	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 6.1e-44
553482003933	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482003934	carbohydrate binding site [chemical binding]; other site
553482003935	pullulanase, type I; Region: pulA_typeI; TIGR02104
553482003936	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
553482003937	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
553482003938	Ca binding site [ion binding]; other site
553482003939	active site
553482003940	catalytic site [active]
553482003941	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 5.1e-07
553482003942	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 8.4e-11
553482003943	CDS contains a frameshift after codon 270. Frameshift occurs at a poly G pentamer. Similar to Streptococcus mutans 1,4-alpha-glucan branching enzyme GlgB UniProt:Q8DT52 (EMBL:AE014133 (628 aa) fasta scores: E()=1.1e-209, 74.682% id in 628 aa
553482003944	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 3e-18
553482003945	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
553482003946	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
553482003947	ligand binding site; other site
553482003948	oligomer interface; other site
553482003949	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
553482003950	dimer interface [polypeptide binding]; other site
553482003951	N-terminal domain interface [polypeptide binding]; other site
553482003952	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5.5e-77
553482003953	PS00808 ADP-glucose pyrophosphorylase signature 1.
553482003954	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 48
553482003955	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.022
553482003956	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
553482003957	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
553482003958	active site
553482003959	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
553482003960	dimer interface [polypeptide binding]; other site
553482003961	N-terminal domain interface [polypeptide binding]; other site
553482003962	sulfate 1 binding site; other site
553482003963	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.5e-05
553482003964	glycogen synthase; Provisional; Region: glgA; PRK00654
553482003965	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
553482003966	ADP-binding pocket [chemical binding]; other site
553482003967	homodimer interface [polypeptide binding]; other site
553482003968	HMMPfam hit to PF08323, Starch synthase catalytic domain, score 4.1e-133
553482003969	HMMPfam hit to PF00534, Glycosyl transferases group, score 6.9e-05
553482003970	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
553482003971	homodimer interface [polypeptide binding]; other site
553482003972	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
553482003973	active site pocket [active]
553482003974	HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 0
553482003975	ATP synthase subunit C; Region: ATP-synt_C; cl00466
553482003976	HMMPfam hit to PF00137, ATP synthase subunit C, score 0.00057
553482003977	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003978	2 transmembrane helices predicted for SEQ0915 by TMHMM2.0 at aa 4-26 and 42-64
553482003979	PS00605 ATP synthase c subunit signature.
553482003980	ATP synthase A chain; Region: ATP-synt_A; cl00413
553482003981	HMMPfam hit to PF00119, ATP synthase A chain, score 2.3e-50
553482003982	5 transmembrane helices predicted for SEQ0916 by TMHMM2.0 at aa 15-37, 75-97, 112-134, 167-189 and 199-221
553482003983	PS00449 ATP synthase a subunit signature.
553482003984	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003985	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
553482003986	Plant ATP synthase F0; Region: YMF19; cl07975
553482003987	HMMPfam hit to PF00430, ATP synthase B/B' CF(0), score 6.8e-21
553482003988	1 transmembrane helix predicted for SEQ0917 by TMHMM2.0 at aa 12-34
553482003989	Plant ATP synthase F0; Region: YMF19; cl07975
553482003990	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
553482003991	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
553482003992	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; cl15275
553482003993	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
553482003994	beta subunit interaction interface [polypeptide binding]; other site
553482003995	Walker A motif; other site
553482003996	ATP binding site [chemical binding]; other site
553482003997	Walker B motif; other site
553482003998	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
553482003999	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 1.4e-20
553482004000	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 3.6e-116
553482004001	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004002	PS00152 ATP synthase alpha and beta subunits signature.
553482004003	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 6.1e-37
553482004004	ATP synthase; Region: ATP-synt; cl00365
553482004005	F0F1 ATP synthase subunit gamma; Provisional; Region: PRK13422
553482004006	HMMPfam hit to PF00231, ATP synthase, score 2.6e-122
553482004007	PS00153 ATP synthase gamma subunit signature.
553482004008	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
553482004009	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; cl15275
553482004010	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
553482004011	alpha subunit interaction interface [polypeptide binding]; other site
553482004012	Walker A motif; other site
553482004013	ATP binding site [chemical binding]; other site
553482004014	Walker B motif; other site
553482004015	inhibitor binding site; inhibition site
553482004016	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
553482004017	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 8.5e-26
553482004018	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.1e-98
553482004019	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004020	PS00152 ATP synthase alpha and beta subunits signature.
553482004021	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 7.8e-48
553482004022	ATP synthase CF1 epsilon subunit; Region: atpE; CHL00063
553482004023	ATP synthase, Delta/Epsilon chain, beta-sandwich domain; Region: ATP-synt_DE_N; cl10033
553482004024	ATP synthase, Delta/Epsilon chain, long alpha-helix domain; Region: ATP-synt_DE; pfam00401
553482004025	HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta, score 3.6e-30
553482004026	HMMPfam hit to PF00401, ATP synthase, Delta/Epsilon chain, long, score 1.4e-08
553482004027	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004028	Helix-turn-helix domains; Region: HTH; cl00088
553482004029	HMMPfam hit to PF01527, Transposase, score 0.00051
553482004030	putative transposase OrfB; Reviewed; Region: PHA02517
553482004031	HTH-like domain; Region: HTH_21; pfam13276
553482004032	Integrase core domain; Region: rve; cl01316
553482004033	Integrase core domain; Region: rve_3; cl15866
553482004034	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-39
553482004035	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
553482004036	2 transmembrane helices predicted for SEQ0925 by TMHMM2.0 at aa 7-26 and 41-60
553482004037	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
553482004038	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
553482004039	hinge; other site
553482004040	active site
553482004041	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 3e-129
553482004042	PS00041 Bacterial regulatory proteins, araC family signature.
553482004043	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
553482004044	1 transmembrane helix predicted for SEQ0927 by TMHMM2.0 at aa 12-34
553482004045	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482004046	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
553482004047	1 transmembrane helix predicted for SEQ0928 by TMHMM2.0 at aa 7-29
553482004048	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 2.9e-12
553482004049	PS01070 DNA/RNA non-specific endonucleases active site.
553482004050	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
553482004051	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
553482004052	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
553482004053	dimer interface [polypeptide binding]; other site
553482004054	motif 1; other site
553482004055	active site
553482004056	motif 2; other site
553482004057	motif 3; other site
553482004058	HMMPfam hit to PF02912, Aminoacyl tRNA synthetase class II, N, score 3.2e-28
553482004059	HMMPfam hit to PF01409, tRNA synthetases class II core domain, score 2.2e-170
553482004060	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482004061	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
553482004062	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
553482004063	putative tRNA-binding site [nucleotide binding]; other site
553482004064	B3/4 domain; Region: B3_4; cl11458
553482004065	tRNA synthetase B5 domain; Region: B5; cl08394
553482004066	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
553482004067	dimer interface [polypeptide binding]; other site
553482004068	motif 1; other site
553482004069	motif 3; other site
553482004070	motif 2; other site
553482004071	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; cl08386
553482004072	HMMPfam hit to PF01588, tRNA binding domain, score 3.1e-20
553482004073	HMMPfam hit to PF03483, B3/4 domain, score 2.6e-94
553482004074	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004075	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004076	HMMPfam hit to PF03484, tRNA synthetase B5 domain, score 2.5e-24
553482004077	HMMPfam hit to PF03147, Ferredoxin-fold anticodon binding domain, score 2e-27
553482004078	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004079	FtsX-like permease family; Region: FtsX; cl15850
553482004080	4 transmembrane helices predicted for SEQ0931 by TMHMM2.0 at aa 13-35, 240-262, 282-304 and 324-346
553482004081	HMMPfam hit to PF02687, Predicted permease, score 2.8e-21
553482004082	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004083	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482004084	Walker A/P-loop; other site
553482004085	ATP binding site [chemical binding]; other site
553482004086	Q-loop/lid; other site
553482004087	ABC transporter signature motif; other site
553482004088	Walker B; other site
553482004089	D-loop; other site
553482004090	H-loop/switch region; other site
553482004091	HMMPfam hit to PF00005, ABC transporter, score 1.6e-53
553482004092	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004093	PS00211 ABC transporters family signature.
553482004094	1 transmembrane helix predicted for SEQ0933 by TMHMM2.0 at aa 13-32
553482004095	HMMPfam hit to PF01468, GA module, score 3.3e-19
553482004096	HMMPfam hit to PF00746, Gram positive anchor, score 6.2e-12
553482004097	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004098	CDS contains a nonsense mutation (ochre) after codon 43. Similar to Streptococcus agalactiae serotype Ia transcriptional regulator, TetR family UniProt:Q3K2A4 (EMBL:CP000114 (176 aa) fasta scores: E()=1.4e-13, 31.765% id in 170 aa
553482004099	Collagen binding domain; Region: Collagen_bind; pfam05737
553482004100	Collagen-binding protein B domain, mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by the repetitive B region; the B region has one to four 23 kDa repeat units (B1-B4). The B repeat...; Region: CollagenBindB; cd00222
553482004101	putative Ca2+ binding sites [ion binding]; other site
553482004102	domain interaction interfaces; other site
553482004103	putative ligand binding motif; other site
553482004104	Collagen-binding protein B domain, mediates bacterial adherence to collagen; the primary sequence has a non-repetitive, collagen-binding A region, followed by the repetitive B region; the B region has one to four 23 kDa repeat units (B1-B4). The B repeat...; Region: CollagenBindB; cd00222
553482004105	putative Ca2+ binding sites [ion binding]; other site
553482004106	domain interaction interfaces; other site
553482004107	putative ligand binding motif; other site
553482004108	HMMPfam hit to PF05737, Collagen binding domain, score 1.7e-60
553482004109	HMMPfam hit to PF05738, Cna protein B-type domain, score 0.00033
553482004110	HMMPfam hit to PF05738, Cna protein B-type domain, score 1.7e-07
553482004111	HMMPfam hit to PF05738, Cna protein B-type domain, score 0.032
553482004112	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004113	1 transmembrane helix predicted for SEQ0935 by TMHMM2.0 at aa 624-646
553482004114	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
553482004115	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl01383
553482004116	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482004117	HMMPfam hit to PF05738, Cna protein B-type domain, score 1.3e-08
553482004118	HMMPfam hit to PF00746, Gram positive anchor, score 0.00046
553482004119	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004120	1 transmembrane helix predicted for SEQ0936 by TMHMM2.0 at aa 453-475
553482004121	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
553482004122	active site
553482004123	catalytic site [active]
553482004124	2 transmembrane helices predicted for SEQ0937 by TMHMM2.0 at aa 5-27 and 241-263
553482004125	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004126	HMMPfam hit to PF04203, Sortase family, score 2e-57
553482004127	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482004128	Mac 1; Region: Mac-1; pfam09028
553482004129	HMMPfam hit to PF04650, YSIRK type signal peptide, score 0.00048
553482004130	1 transmembrane helix predicted for SEQ0938 by TMHMM2.0 at aa 21-43
553482004131	HMMPfam hit to PF00746, Gram positive anchor, score 4.1e-10
553482004132	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004133	1 transmembrane helix predicted for SEQ0939 by TMHMM2.0 at aa 389-411
553482004134	gene remnant. Similar to the N-terminal region of Shewanella frigidimarina ISSod11, transposase. UniProt:Q3NJZ7 (EMBL:AAIV01000012 (196 aa) fasta scores: E()=3.8e-09, 28.571% id in 105 aa
553482004135	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482004136	pullulanase, extracellular, Gram-positive; Region: pullulan_Gpos; TIGR02102
553482004137	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482004138	carbohydrate binding site [chemical binding]; other site
553482004139	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482004140	carbohydrate binding site [chemical binding]; other site
553482004141	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
553482004142	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
553482004143	Ca binding site [ion binding]; other site
553482004144	active site
553482004145	catalytic site [active]
553482004146	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.3e-07
553482004147	2 transmembrane helices predicted for SEQ0944 by TMHMM2.0 at aa 25-47 and 1210-1232
553482004148	HMMPfam hit to PF03714, Bacterial pullanase-associated domain, score 1.9e-41
553482004149	HMMPfam hit to PF03714, Bacterial pullanase-associated domain, score 2.9e-30
553482004150	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 3.5e-15
553482004151	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.9e-11
553482004152	HMMPfam hit to PF00746, Gram positive anchor, score 7.8e-05
553482004153	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004154	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
553482004155	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
553482004156	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482004157	DNA binding residues [nucleotide binding]
553482004158	PS00217 Sugar transport proteins signature 2.
553482004159	HMMPfam hit to PF04542, Sigma-70 region, score 1.5e-14
553482004160	PS01063 Sigma-70 factors ECF subfamily signature.
553482004161	HMMPfam hit to PF08281, Sigma-70, region, score 7.1e-09
553482004162	HMMPfam hit to PF04545, Sigma-70, region, score 0.0005
553482004163	Predicted integral membrane protein [Function unknown]; Region: COG5660
553482004164	Putative zinc-finger; Region: zf-HC2; cl15806
553482004165	1 transmembrane helix predicted for SEQ0946 by TMHMM2.0 at aa 78-100
553482004166	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
553482004167	putative metal binding residues [ion binding]; other site
553482004168	signature motif; other site
553482004169	dimer interface [polypeptide binding]; other site
553482004170	polyP binding site; other site
553482004171	active site
553482004172	substrate binding site [chemical binding]; other site
553482004173	acceptor-phosphate pocket; other site
553482004174	magnesium transport protein MgtC; Provisional; Region: PRK15385
553482004175	3 transmembrane helices predicted for SEQ0948 by TMHMM2.0 at aa 20-42, 64-86 and 99-121
553482004176	Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 42-63, sequence HTGTAYSKKFNVSLMTLTVLTA
553482004177	CotH protein; Region: CotH; pfam08757
553482004178	1 transmembrane helix predicted for SEQ0949 by TMHMM2.0 at aa 7-25
553482004179	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
553482004180	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
553482004181	DXD motif; other site
553482004182	4 transmembrane helices predicted for SEQ0951 by TMHMM2.0 at aa 13-35, 350-372, 379-401 and 421-443
553482004183	HMMPfam hit to PF03142, Chitin synthase, score 0.00028
553482004184	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.2e-27
553482004185	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482004186	ATP-dependent nuclease subunit B; Region: rexB_recomb; TIGR02774
553482004187	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
553482004188	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
553482004189	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
553482004190	HMMPfam hit to PF00580, UvrD/REP helicase, score 3.2e-82
553482004191	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004192	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482004193	transaminase; Validated; Region: PRK07324
553482004194	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482004195	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482004196	homodimer interface [polypeptide binding]; other site
553482004197	catalytic residue [active]
553482004198	HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.7e-29
553482004199	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0024
553482004200	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
553482004201	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482004202	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482004203	substrate binding pocket [chemical binding]; other site
553482004204	membrane-bound complex binding site; other site
553482004205	hinge residues; other site
553482004206	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.8e-56
553482004207	Ribosomal protein S21; Region: Ribosomal_S21; cl00529
553482004208	HMMPfam hit to PF01165, Ribosomal protein S21, score 1.1e-30
553482004209	PS01181 Ribosomal protein S21 signature.
553482004210	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
553482004211	2 transmembrane helices predicted for SEQ0958 by TMHMM2.0 at aa 13-35 and 68-87
553482004212	PS01327 Large-conductance mechanosensitive channels mscL family signature.
553482004213	DNA primase; Validated; Region: dnaG; PRK05667
553482004214	CHC2 zinc finger; Region: zf-CHC2; cl15369
553482004215	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
553482004216	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
553482004217	active site
553482004218	metal binding site [ion binding]; metal-binding site
553482004219	interdomain interaction site; other site
553482004220	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
553482004221	HMMPfam hit to PF01807, CHC2 zinc finger, score 9.6e-45
553482004222	HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal domai, score 1.3e-51
553482004223	HMMPfam hit to PF01751, Toprim domain, score 1.4e-16
553482004224	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
553482004225	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
553482004226	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
553482004227	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
553482004228	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
553482004229	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482004230	DNA binding residues [nucleotide binding]
553482004231	HMMPfam hit to PF03979, Sigma-70 factor, region, score 1.5e-05
553482004232	HMMPfam hit to PF00140, Sigma-70 factor, region, score 2.2e-15
553482004233	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-29
553482004234	PS00715 Sigma-70 factors family signature 1.
553482004235	HMMPfam hit to PF04539, Sigma-70 region, score 4.5e-41
553482004236	Predicted helix-turn-helix motif with score 985.000, SD 2.54 at aa 234-255, sequence PTPEQIAERMEMTPDKVREILK
553482004237	HMMPfam hit to PF04545, Sigma-70, region, score 1.3e-24
553482004238	Predicted helix-turn-helix motif with score 1807.000, SD 5.34 at aa 327-348, sequence RTLEDVGKVFNVTRERIRQIEA
553482004239	PS00716 Sigma-70 factors family signature 2.
553482004240	Domain of unknown function DUF59; Region: DUF59; cl00941
553482004241	HMMPfam hit to PF01883, Domain of unknown function DUF59, score 1.7e-38
553482004242	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
553482004243	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
553482004244	NADP binding site [chemical binding]; other site
553482004245	active site
553482004246	putative substrate binding site [chemical binding]; other site
553482004247	HMMPfam hit to PF04321, RmlD substrate binding domain, score 4.1e-143
553482004248	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00023
553482004249	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.1e-18
553482004250	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.1e-05
553482004251	HMMPfam hit to PF07993, Male sterility protein, score 0.00036
553482004252	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
553482004253	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482004254	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
553482004255	Probable Catalytic site; other site
553482004256	HMMPfam hit to PF00535, Glycosyl transferase family, score 4e-21
553482004257	ABC-2 type transporter; Region: ABC2_membrane; cl11417
553482004258	HMMPfam hit to PF01061, ABC-2 type transporter, score 1e-15
553482004259	6 transmembrane helices predicted for SEQ0965 by TMHMM2.0 at aa 28-50, 65-87, 107-129, 144-166, 173-195 and 235-257
553482004260	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
553482004261	ABC_KpsT_Wzt   The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export.  Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and...; Region: ABC_KpsT_Wzt; cd03220
553482004262	Walker A/P-loop; other site
553482004263	ATP binding site [chemical binding]; other site
553482004264	Q-loop/lid; other site
553482004265	ABC transporter signature motif; other site
553482004266	Walker B; other site
553482004267	D-loop; other site
553482004268	H-loop/switch region; other site
553482004269	HMMPfam hit to PF00005, ABC transporter, score 2.3e-39
553482004270	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004271	PS00211 ABC transporters family signature.
553482004272	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
553482004273	active site
553482004274	HMMPfam hit to PF00535, Glycosyl transferase family, score 5.9e-32
553482004275	Rhamnan synthesis protein F; Region: RgpF; cl01529
553482004276	HMMPfam hit to PF05045, Rhamnan synthesis protein F, score 3.3e-280
553482004277	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
553482004278	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
553482004279	Ligand binding site; other site
553482004280	Putative Catalytic site; other site
553482004281	DXD motif; other site
553482004282	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.2e-31
553482004283	3 transmembrane helices predicted for SEQ0970 by TMHMM2.0 at aa 4-21, 34-56 and 66-85
553482004284	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
553482004285	MatE; Region: MatE; cl10513
553482004286	12 transmembrane helices predicted for SEQ0971 by TMHMM2.0 at aa 13-35, 46-63, 83-102, 112-134, 147-164, 168-186, 207-226, 246-268, 295-317, 332-354, 361-380 and 385-407
553482004287	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004288	Predicted membrane protein [Function unknown]; Region: COG4713
553482004289	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl15769
553482004290	12 transmembrane helices predicted for SEQ0972 by TMHMM2.0 at aa 15-33, 40-57, 61-80, 151-173, 178-200, 227-244, 259-281, 294-316, 370-392, 405-427, 442-461 and 473-490
553482004291	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482004292	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
553482004293	HMMPfam hit to PF00534, Glycosyl transferases group, score 7.4e-28
553482004294	Sulfatase; Region: Sulfatase; cl10460
553482004295	8 transmembrane helices predicted for SEQ0974 by TMHMM2.0 at aa 18-40, 57-74, 136-158, 163-185, 195-217, 222-241, 269-291 and 303-325
553482004296	HMMPfam hit to PF00884, Sulfatase, score 4.4e-56
553482004297	UDP-glucose 4-epimerase; Region: PLN02240
553482004298	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
553482004299	NAD binding site [chemical binding]; other site
553482004300	homodimer interface [polypeptide binding]; other site
553482004301	active site
553482004302	substrate binding site [chemical binding]; other site
553482004303	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0043
553482004304	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.4e-78
553482004305	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 3.6e-07
553482004306	HMMPfam hit to PF07993, Male sterility protein, score 0.0016
553482004307	peptidase T; Region: peptidase-T; TIGR01882
553482004308	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
553482004309	metal binding site [ion binding]; metal-binding site
553482004310	dimer interface [polypeptide binding]; other site
553482004311	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
553482004312	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 0.00027
553482004313	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
553482004314	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 3.4e-22
553482004315	2 transmembrane helices predicted for SEQ0977 by TMHMM2.0 at aa 20-38 and 45-67
553482004316	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
553482004317	Lysin domain, found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function; Region: LysM; cl00107
553482004318	1 transmembrane helix predicted for SEQ0979 by TMHMM2.0 at aa 30-52
553482004319	cytidylate kinase; Provisional; Region: cmk; PRK00023
553482004320	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
553482004321	CMP-binding site; other site
553482004322	The sites determining sugar specificity; other site
553482004323	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004324	HMMPfam hit to PF02224, Cytidylate kinase, score 4.3e-63
553482004325	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
553482004326	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
553482004327	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
553482004328	HMMPfam hit to PF05198, Translation initiation factor IF-3, N-termin, score 1.1e-47
553482004329	PS00938 Initiation factor 3 signature.
553482004330	HMMPfam hit to PF00707, Translation initiation factor IF-3, C-termin, score 1.4e-44
553482004331	Ribosomal protein L35; Region: Ribosomal_L35p; cl00392
553482004332	HMMPfam hit to PF01632, Ribosomal protein L35, score 7.4e-20
553482004333	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
553482004334	23S rRNA binding site [nucleotide binding]; other site
553482004335	L21 binding site [polypeptide binding]; other site
553482004336	L13 binding site [polypeptide binding]; other site
553482004337	HMMPfam hit to PF00453, Ribosomal protein L20, score 3.2e-66
553482004338	PS00937 Ribosomal protein L20 signature.
553482004339	Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 63-84, sequence TRINAAARMNGLSYSQLMHGLK
553482004340	3 transmembrane helices predicted for SEQ0984 by TMHMM2.0 at aa 7-26, 105-127 and 134-156
553482004341	HMMPfam hit to PF00746, Gram positive anchor, score 1.7e-05
553482004342	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004343	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
553482004344	Sulfatase; Region: Sulfatase; cl10460
553482004345	HMMPfam hit to PF00884, Sulfatase, score 7.2e-30
553482004346	5 transmembrane helices predicted for SEQ0985 by TMHMM2.0 at aa 13-35, 45-67, 74-96, 126-148 and 161-180
553482004347	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004348	Helix-turn-helix domains; Region: HTH; cl00088
553482004349	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004350	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004351	HMMPfam hit to PF02178, no description, score 0.21
553482004352	putative transposase OrfB; Reviewed; Region: PHA02517
553482004353	HTH-like domain; Region: HTH_21; pfam13276
553482004354	Integrase core domain; Region: rve; cl01316
553482004355	Integrase core domain; Region: rve_3; cl15866
553482004356	HMMPfam hit to PF00665, Integrase core domain, score 1.2e-37
553482004357	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
553482004358	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
553482004359	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
553482004360	3-dehydroquinate dehydratase, type I; Region: aroD; TIGR01093
553482004361	active site
553482004362	catalytic residue [active]
553482004363	dimer interface [polypeptide binding]; other site
553482004364	HMMPfam hit to PF01487, Type I 3-dehydroquinase, score 1.3e-39
553482004365	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
553482004366	Tetramer interface [polypeptide binding]; other site
553482004367	active site
553482004368	FMN-binding site [chemical binding]; other site
553482004369	HMMPfam hit to PF01264, Chorismate synthase, score 2.3e-161
553482004370	PS00787 Chorismate synthase signature 1.
553482004371	PS00788 Chorismate synthase signature 2.
553482004372	Protein of unknown function (DUF964); Region: DUF964; cl01483
553482004373	HMMPfam hit to PF06133, Protein of unknown function (DUF964), score 3.9e-56
553482004374	glutathione reductase; Validated; Region: PRK06116
553482004375	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482004376	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482004377	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00095
553482004378	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.7e-64
553482004379	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482004380	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.4e-30
553482004381	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 8.8e-51
553482004382	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK13108
553482004383	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
553482004384	cysteine desulfurase DndA; Region: DNA_S_dndA; TIGR03235
553482004385	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482004386	catalytic residue [active]
553482004387	HMMPfam hit to PF00266, Aminotransferase class-V, score 5.9e-71
553482004388	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0014
553482004389	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482004390	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
553482004391	THUMP domain; Region: THUMP; cl12076
553482004392	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
553482004393	Ligand Binding Site [chemical binding]; other site
553482004394	HMMPfam hit to PF02926, THUMP domain, score 5.4e-15
553482004395	HMMPfam hit to PF02568, Thiamine biosynthesis protein (ThiI), score 7.3e-94
553482004396	HMMPfam hit to PF06508, ExsB, score 0.0012
553482004397	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004398	Mac 1; Region: Mac-1; pfam09028
553482004399	1 transmembrane helix predicted for SEQ0999 by TMHMM2.0 at aa 12-34
553482004400	1 transmembrane helix predicted for SEQ1001 by TMHMM2.0 at aa 15-37
553482004401	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
553482004402	5 transmembrane helices predicted for SEQ1002 by TMHMM2.0 at aa 15-34, 55-74, 89-111, 143-162 and 172-194
553482004403	6 transmembrane helices predicted for SEQ1003 by TMHMM2.0 at aa 13-35, 58-80, 110-132, 160-182, 189-211 and 235-257
553482004404	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482004405	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482004406	Walker A/P-loop; other site
553482004407	ATP binding site [chemical binding]; other site
553482004408	Q-loop/lid; other site
553482004409	ABC transporter signature motif; other site
553482004410	Walker B; other site
553482004411	D-loop; other site
553482004412	H-loop/switch region; other site
553482004413	HMMPfam hit to PF00005, ABC transporter, score 9.9e-34
553482004414	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004415	Predicted transcriptional regulators [Transcription]; Region: COG1725
553482004416	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004417	DNA-binding site [nucleotide binding]; DNA binding site
553482004418	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.4e-10
553482004419	Predicted helix-turn-helix motif with score 1258.000, SD 3.47 at aa 35-56, sequence PTVREYAEIAGVNPNTMQRALT
553482004420	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK07279
553482004421	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
553482004422	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
553482004423	generic binding surface II; other site
553482004424	generic binding surface I; other site
553482004425	HMMPfam hit to PF02811, PHP domain, score 1.1e-07
553482004426	HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 5.3e-242
553482004427	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3.3e-11
553482004428	putative transposase OrfB; Reviewed; Region: PHA02517
553482004429	HTH-like domain; Region: HTH_21; pfam13276
553482004430	Integrase core domain; Region: rve; cl01316
553482004431	Integrase core domain; Region: rve_3; cl15866
553482004432	HMMPfam hit to PF00665, Integrase core domain, score 1.2e-37
553482004433	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004434	Helix-turn-helix domains; Region: HTH; cl00088
553482004435	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004436	HMMPfam hit to PF02178, no description, score 0.21
553482004437	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004438	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
553482004439	active site
553482004440	ADP/pyrophosphate binding site [chemical binding]; other site
553482004441	dimerization interface [polypeptide binding]; other site
553482004442	allosteric effector site; other site
553482004443	fructose-1,6-bisphosphate binding site; other site
553482004444	HMMPfam hit to PF00365, Phosphofructokinase, score 3.8e-173
553482004445	pyruvate kinase; Provisional; Region: PRK05826
553482004446	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl09155
553482004447	domain interfaces; other site
553482004448	active site
553482004449	HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 1.9e-203
553482004450	HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 0.0022
553482004451	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 9.7e-51
553482004452	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
553482004453	conjugative transfer signal peptidase TraF; Region: TraF_Ti; TIGR02771
553482004454	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
553482004455	1 transmembrane helix predicted for SEQ1013 by TMHMM2.0 at aa 9-28
553482004456	HMMPfam hit to PF00717, Peptidase S24-like, score 0.0004
553482004457	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
553482004458	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
553482004459	glutaminase active site [active]
553482004460	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
553482004461	dimer interface [polypeptide binding]; other site
553482004462	active site
553482004463	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
553482004464	dimer interface [polypeptide binding]; other site
553482004465	active site
553482004466	PS00443 Glutamine amidotransferases class-II active site.
553482004467	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 7.4e-29
553482004468	HMMPfam hit to PF01380, SIS domain, score 2.7e-30
553482004469	HMMPfam hit to PF01380, SIS domain, score 8.4e-17
553482004470	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
553482004471	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
553482004472	PhnA protein; Region: PhnA; pfam03831
553482004473	HMMPfam hit to PF08274, PhnA Zinc-Ribbon, score 3.8e-14
553482004474	HMMPfam hit to PF03831, PhnA protein, score 2.6e-35
553482004475	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004476	dimer interface [polypeptide binding]; other site
553482004477	conserved gate region; other site
553482004478	ABC-ATPase subunit interface; other site
553482004479	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.8e-33
553482004480	3 transmembrane helices predicted for SEQ1016 by TMHMM2.0 at aa 15-37, 50-72 and 179-201
553482004481	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004482	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482004483	Walker A/P-loop; other site
553482004484	ATP binding site [chemical binding]; other site
553482004485	Q-loop/lid; other site
553482004486	ABC transporter signature motif; other site
553482004487	Walker B; other site
553482004488	D-loop; other site
553482004489	H-loop/switch region; other site
553482004490	HMMPfam hit to PF00005, ABC transporter, score 8e-56
553482004491	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004492	PS00211 ABC transporters family signature.
553482004493	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482004494	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482004495	substrate binding pocket [chemical binding]; other site
553482004496	membrane-bound complex binding site; other site
553482004497	hinge residues; other site
553482004498	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004499	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.1e-80
553482004500	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
553482004501	Cation efflux family; Region: Cation_efflux; cl00316
553482004502	HMMPfam hit to PF01545, Cation efflux family, score 2.2e-90
553482004503	4 transmembrane helices predicted for SEQ1019 by TMHMM2.0 at aa 15-37, 84-106, 116-138 and 184-206
553482004504	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
553482004505	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
553482004506	HMMPfam hit to PF01235, Sodium:alanine symporter family, score 2.1e-165
553482004507	11 transmembrane helices predicted for SEQ1020 by TMHMM2.0 at aa 25-47, 71-93, 103-125, 155-177, 192-214, 221-238, 248-270, 316-338, 358-380, 385-407 and 422-444
553482004508	PS00873 Sodium:alanine symporter family signature.
553482004509	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
553482004510	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482004511	Family description; Region: UvrD_C_2; cl15862
553482004512	HMMPfam hit to PF00580, UvrD/REP helicase, score 1.2e-222
553482004513	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004514	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
553482004515	3 transmembrane helices predicted for SEQ1022 by TMHMM2.0 at aa 4-26, 33-55 and 60-82
553482004516	HMMPfam hit to PF04226, Transglycosylase associated protein, score 2.4e-14
553482004517	2 transmembrane helices predicted for SEQ1023 by TMHMM2.0 at aa 7-26 and 57-79
553482004518	Small integral membrane protein (DUF2273); Region: DUF2273; cl11575
553482004519	2 transmembrane helices predicted for SEQ1024 by TMHMM2.0 at aa 7-29 and 33-55
553482004520	Asp23 family; Region: Asp23; cl00574
553482004521	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 1.5e-40
553482004522	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482004523	PS00327 Bacterial rhodopsins retinal binding site.
553482004524	CsbD-like; Region: CsbD; cl15799
553482004525	HMMPfam hit to PF05532, CsbD-like, score 4.7e-21
553482004526	Asp23 family; Region: Asp23; cl00574
553482004527	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 3.2e-42
553482004528	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004529	DNA-binding site [nucleotide binding]; DNA binding site
553482004530	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15357
553482004531	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.7e-09
553482004532	Predicted helix-turn-helix motif with score 1173.000, SD 3.18 at aa 36-57, sequence KSRTTIASTFKVSPETARKGLN
553482004533	HMMPfam hit to PF02080, TrkA-C domain, score 3.8e-15
553482004534	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482004535	Helix-turn-helix domains; Region: HTH; cl00088
553482004536	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.3e-06
553482004537	Predicted helix-turn-helix motif with score 1070.000, SD 2.83 at aa 28-49, sequence ITVSDLTKKAGVNRGTFYLHYR
553482004538	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004539	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482004540	Walker A/P-loop; other site
553482004541	ATP binding site [chemical binding]; other site
553482004542	Q-loop/lid; other site
553482004543	ABC transporter signature motif; other site
553482004544	Walker B; other site
553482004545	D-loop; other site
553482004546	H-loop/switch region; other site
553482004547	HMMPfam hit to PF00005, ABC transporter, score 3.3e-59
553482004548	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004549	PS00211 ABC transporters family signature.
553482004550	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004551	FtsX-like permease family; Region: FtsX; cl15850
553482004552	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004553	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482004554	FtsX-like permease family; Region: FtsX; cl15850
553482004555	8 transmembrane helices predicted for SEQ1031 by TMHMM2.0 at aa 21-43, 344-366, 397-419, 439-461, 517-539, 750-769, 803-825 and 840-862
553482004556	HMMPfam hit to PF02687, Predicted permease, score 6.2e-29
553482004557	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004558	HMMPfam hit to PF02687, Predicted permease, score 2.1e-22
553482004559	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
553482004560	Predicted membrane protein [Function unknown]; Region: COG4129
553482004561	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
553482004562	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
553482004563	HMMPfam hit to PF06081, Bacterial protein of unknown function (DUF93, score 5e-133
553482004564	4 transmembrane helices predicted for SEQ1033 by TMHMM2.0 at aa 15-37, 58-80, 84-106 and 119-141
553482004565	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004566	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
553482004567	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
553482004568	PS00659 Glycosyl hydrolases family 5 signature.
553482004569	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
553482004570	PseudoU_synth_EcTruB: Pseudouridine synthase, Escherichia coli TruB like. This group consists of bacterial pseudouridine synthases similar to E. coli TruB and Mycobacterium tuberculosis TruB. Pseudouridine synthases catalyze the isomerization of specific...; Region: PseudoU_synth_EcTruB; cd02573
553482004571	RNA binding site [nucleotide binding]; other site
553482004572	active site
553482004573	HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N term, score 8.2e-73
553482004574	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
553482004575	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
553482004576	active site
553482004577	Riboflavin kinase; Region: Flavokinase; cl03312
553482004578	HMMPfam hit to PF06574, FAD synthetase, score 3.5e-60
553482004579	HMMPfam hit to PF01687, Riboflavin kinase, score 2.3e-51
553482004580	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
553482004581	ArsC family; Region: ArsC; pfam03960
553482004582	putative catalytic residues [active]
553482004583	thiol/disulfide switch; other site
553482004584	HMMPfam hit to PF03960, ArsC family, score 1.2e-58
553482004585	Uncharacterized protein family (UPF0223); Region: UPF0223; cl11484
553482004586	HMMPfam hit to PF05256, Uncharacterised protein family (UPF0223), score 6.2e-55
553482004587	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
553482004588	active site
553482004589	HMMPfam hit to PF00459, Inositol monophosphatase family, score 2e-30
553482004590	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
553482004591	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004592	S-adenosylmethionine binding site [chemical binding]; other site
553482004593	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; cl01283
553482004594	HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 4.2e-24
553482004595	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004596	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482004597	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.7e-08
553482004598	1 transmembrane helix predicted for SEQ1042 by TMHMM2.0 at aa 7-26
553482004599	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004600	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004601	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004602	dimer interface [polypeptide binding]; other site
553482004603	conserved gate region; other site
553482004604	putative PBP binding loops; other site
553482004605	ABC-ATPase subunit interface; other site
553482004606	7 transmembrane helices predicted for SEQ1043 by TMHMM2.0 at aa 24-46, 90-112, 127-149, 156-178, 207-229, 242-264 and 279-301
553482004607	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.9e-22
553482004608	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
553482004609	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004610	dimer interface [polypeptide binding]; other site
553482004611	conserved gate region; other site
553482004612	putative PBP binding loops; other site
553482004613	ABC-ATPase subunit interface; other site
553482004614	4 transmembrane helices predicted for SEQ1044 by TMHMM2.0 at aa 12-34, 66-88, 109-131 and 258-280
553482004615	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.9e-36
553482004616	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482004617	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
553482004618	Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient.  The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes.  The PstS protein...; Region: ABC_PstB_phosphate_transporter; cd03260
553482004619	Walker A/P-loop; other site
553482004620	ATP binding site [chemical binding]; other site
553482004621	Q-loop/lid; other site
553482004622	ABC transporter signature motif; other site
553482004623	Walker B; other site
553482004624	D-loop; other site
553482004625	H-loop/switch region; other site
553482004626	HMMPfam hit to PF00005, ABC transporter, score 2e-49
553482004627	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004628	PS00211 ABC transporters family signature.
553482004629	phosphate transporter ATP-binding protein; Provisional; Region: PRK14239
553482004630	Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient.  The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes.  The PstS protein...; Region: ABC_PstB_phosphate_transporter; cd03260
553482004631	Walker A/P-loop; other site
553482004632	ATP binding site [chemical binding]; other site
553482004633	Q-loop/lid; other site
553482004634	ABC transporter signature motif; other site
553482004635	Walker B; other site
553482004636	D-loop; other site
553482004637	H-loop/switch region; other site
553482004638	HMMPfam hit to PF00005, ABC transporter, score 2.4e-51
553482004639	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004640	PS00211 ABC transporters family signature.
553482004641	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
553482004642	PhoU domain; Region: PhoU; pfam01895
553482004643	PhoU domain; Region: PhoU; pfam01895
553482004644	HMMPfam hit to PF01895, PhoU family, score 9.4e-31
553482004645	HMMPfam hit to PF01895, PhoU family, score 6.7e-12
553482004646	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
553482004647	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
553482004648	Zn binding site [ion binding]; other site
553482004649	HMMPfam hit to PF01433, Peptidase family M1, score 1.1e-168
553482004650	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482004651	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482004652	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482004653	active site
553482004654	phosphorylation site [posttranslational modification]
553482004655	intermolecular recognition site; other site
553482004656	dimerization interface [polypeptide binding]; other site
553482004657	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482004658	DNA binding site [nucleotide binding]
553482004659	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-25
553482004660	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3e-14
553482004661	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482004662	dimer interface [polypeptide binding]; other site
553482004663	phosphorylation site [posttranslational modification]
553482004664	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482004665	ATP binding site [chemical binding]; other site
553482004666	Mg2+ binding site [ion binding]; other site
553482004667	G-X-G motif; other site
553482004668	2 transmembrane helices predicted for SEQ1050 by TMHMM2.0 at aa 7-29 and 177-199
553482004669	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.4e-10
553482004670	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.1e-33
553482004671	1 transmembrane helix predicted for SEQ1051 by TMHMM2.0 at aa 15-34
553482004672	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is 'interfacial activation', the process of becoming...; Region: Lipase; cl14883
553482004673	nucleophilic elbow; other site
553482004674	catalytic triad; other site
553482004675	PS00120 Lipases, serine active site.
553482004676	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004677	Ribosomal protein S20; Region: Ribosomal_S20p; cl00384
553482004678	HMMPfam hit to PF01649, Ribosomal protein S20, score 8.5e-20
553482004679	pantothenate kinase; Provisional; Region: PRK05439
553482004680	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point in...; Region: PanK; cd02025
553482004681	ATP-binding site [chemical binding]; other site
553482004682	CoA-binding site [chemical binding]; other site
553482004683	Mg2+-binding site [ion binding]; other site
553482004684	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 4.2e-07
553482004685	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004687	S-adenosylmethionine binding site [chemical binding]; other site
553482004688	HMMPfam hit to PF05175, Methyltransferase small domain, score 1.8e-73
553482004689	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482004690	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
553482004691	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
553482004692	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
553482004693	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; cl06734
553482004694	HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 1.2e-22
553482004695	HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 2.6e-30
553482004696	PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature.
553482004697	HMMPfam hit to PF07831, Pyrimidine nucleoside phosphorylase C, score 2.4e-25
553482004698	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
553482004699	intersubunit interface [polypeptide binding]; other site
553482004700	active site
553482004701	catalytic residue [active]
553482004702	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 2.6e-81
553482004703	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
553482004704	active site
553482004705	catalytic motif [active]
553482004706	Zn binding site [ion binding]; other site
553482004707	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 1.2e-20
553482004708	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482004709	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
553482004710	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
553482004711	ligand binding site [chemical binding]; other site
553482004712	HMMPfam hit to PF02608, Basic membrane protein, score 1.4e-73
553482004713	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004714	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004715	PS00227 Tubulin subunits alpha, beta, and gamma signature.
553482004716	PS00146 Beta-lactamase class-A active site.
553482004717	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
553482004718	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482004719	Walker A/P-loop; other site
553482004720	ATP binding site [chemical binding]; other site
553482004721	Q-loop/lid; other site
553482004722	ABC transporter signature motif; other site
553482004723	Walker B; other site
553482004724	D-loop; other site
553482004725	H-loop/switch region; other site
553482004726	This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos).  The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses; Region: ABC_Carb_Monos_II; cd03215
553482004727	HMMPfam hit to PF00005, ABC transporter, score 2.5e-52
553482004728	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004729	HMMPfam hit to PF00005, ABC transporter, score 5.7e-20
553482004730	PS00211 ABC transporters family signature.
553482004731	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
553482004732	TM-ABC transporter signature motif; other site
553482004733	10 transmembrane helices predicted for SEQ1063 by TMHMM2.0 at aa 9-31, 51-70, 75-97, 107-129, 134-156, 194-213, 242-264, 268-290, 295-317 and 322-344
553482004734	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.4e-55
553482004735	CDS contains a frameshift after codon 47. Frameshift occurs at a poly G octamer. Similar to Streptococcus pyogenes serotype M3 sugar ABC transporter UniProt:Q878Q1 (EMBL:BA000034 (318 aa) fasta scores: E()=3.7e-103, 92.453% id in 318 aa
553482004736	2 transmembrane helices predicted for SEQ1064 by TMHMM2.0 at aa 4-26 and 39-61
553482004737	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 5.8e-05
553482004738	6 transmembrane helices predicted for SEQ1065 by TMHMM2.0 at aa 20-42, 77-94, 120-142, 146-168, 173-195 and 205-227
553482004739	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482004740	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482004741	HMMPfam hit to PF01610, Transposase, score 1.5e-47
553482004742	Predicted helix-turn-helix motif with score 1424.000, SD 4.04 at aa 118-139, sequence KALTHIASKLAISTSTVYRKLK
553482004743	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
553482004744	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
553482004745	active site
553482004746	substrate binding site [chemical binding]; other site
553482004747	metal binding site [ion binding]; metal-binding site
553482004748	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 0.0012
553482004749	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 2e-05
553482004750	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 0.0092
553482004751	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 1.7e-56
553482004752	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482004753	Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 75-96, sequence ESKGEAAKKAGVAIAYDSRHFS
553482004754	putative transposase OrfB; Reviewed; Region: PHA02517
553482004755	HTH-like domain; Region: HTH_21; pfam13276
553482004756	Integrase core domain; Region: rve; cl01316
553482004757	Integrase core domain; Region: rve_3; cl15866
553482004758	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482004759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004760	Helix-turn-helix domains; Region: HTH; cl00088
553482004761	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004762	HMMPfam hit to PF02178, no description, score 0.21
553482004763	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004764	Predicted membrane protein [Function unknown]; Region: COG4684
553482004765	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
553482004766	5 transmembrane helices predicted for SEQ1072 by TMHMM2.0 at aa 15-37, 62-84, 99-121, 128-150 and 165-187
553482004767	phosphopantothenoylcysteine decarboxylase; Validated; Region: PRK07313
553482004768	Flavoprotein; Region: Flavoprotein; cl08021
553482004769	HMMPfam hit to PF02441, Flavoprotein, score 6.1e-47
553482004770	DNA / pantothenate metabolism flavoprotein; Region: DFP; cl04410
553482004771	HMMPfam hit to PF04127, DNA / pantothenate metabolism flavoprotein, score 1.6e-62
553482004772	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
553482004773	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
553482004774	Potassium binding sites [ion binding]; other site
553482004775	Cesium cation binding sites [ion binding]; other site
553482004776	HMMPfam hit to PF01268, Formate--tetrahydrofolate ligase, score 0
553482004777	PS00721 Formate--tetrahydrofolate ligase signature 1.
553482004778	CDS contains a frameshift after codon 58 and a nonsense mutation (ochre) after codon 105. CDS appears to be truncated at the C-terminus and lacks a LPxTG motif. Similar to the N-terminal region of Streptococcus agalactiae serotype III hypothetical protein gbs0451 UniProt:Q8E6V8 (EMBL:AL766845 (1233 aa) fasta scores: E()=2.4e-101, 41.704% id in 1115 aa
553482004779	HMMPfam hit to PF00082, Subtilase family, score 2.8e-06
553482004780	HMMPfam hit to PF02225, PA domain, score 3.7e-17
553482004781	PS00138 Serine proteases, subtilase family, serine active site.
553482004782	HMMPfam hit to PF06280, Domain of Unknown Function (DUF1034), score 4.8e-22
553482004783	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
553482004784	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
553482004785	putative active site [active]
553482004786	catalytic site [active]
553482004787	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
553482004788	putative active site [active]
553482004789	catalytic site [active]
553482004790	3 transmembrane helices predicted for SEQ1078 by TMHMM2.0 at aa 20-42, 52-74 and 79-101
553482004791	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 3.7e-10
553482004792	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 5.9e-06
553482004793	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004794	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
553482004795	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482004796	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl15856
553482004797	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 5.1e-45
553482004798	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 1.7e-78
553482004799	ATP cone domain; Region: ATP-cone; pfam03477
553482004800	HMMPfam hit to PF03477, ATP cone domain, score 4e-26
553482004801	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004802	DNA-binding site [nucleotide binding]; DNA binding site
553482004803	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482004804	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482004805	homodimer interface [polypeptide binding]; other site
553482004806	catalytic residue [active]
553482004807	HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.4e-05
553482004808	Predicted helix-turn-helix motif with score 1266.000, SD 3.50 at aa 174-195, sequence HRMEQLATSLGLPYQTIERDVN
553482004809	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 2.2e-11
553482004810	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 28-49, sequence PSIRQLSQQYHCSKDTVQRALL
553482004811	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
553482004812	dimer interface [polypeptide binding]; other site
553482004813	pyridoxal binding site [chemical binding]; other site
553482004814	ATP binding site [chemical binding]; other site
553482004815	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004816	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl01942
553482004817	6 transmembrane helices predicted for SEQ1084 by TMHMM2.0 at aa 7-25, 29-46, 66-88, 98-115, 122-141 and 145-164
553482004818	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482004819	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
553482004820	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482004821	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482004822	ABC transporter; Region: ABC_tran_2; pfam12848
553482004823	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482004824	HMMPfam hit to PF00005, ABC transporter, score 1e-42
553482004825	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004826	PS00211 ABC transporters family signature.
553482004827	HMMPfam hit to PF00005, ABC transporter, score 4.6e-35
553482004828	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004829	PS00211 ABC transporters family signature.
553482004830	CDS contains a frameshift after codon 160. Similar to Streptococcus pyogenes serotype M1 hypothetical protein Spy1158 (hypothetical protein). UniProt:Q99ZN0 (EMBL:AE006557 (303 aa) fasta scores: E()=2.5e-80, 76.254% id in 299 aa
553482004831	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 2.6e-26
553482004832	Haemolysin-III related; Region: HlyIII; cl03831
553482004833	6 transmembrane helices predicted for SEQ1090 by TMHMM2.0 at aa 20-42, 49-71, 106-128, 141-160, 164-186 and 193-215
553482004834	HMMPfam hit to PF03006, Haemolysin-III related, score 1.5e-59
553482004835	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
553482004836	Methyltransferase domain; Region: Methyltransf_31; pfam13847
553482004837	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004838	S-adenosylmethionine binding site [chemical binding]; other site
553482004839	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 0.00059
553482004840	HMMPfam hit to PF08241, Methyltransferase domain, score 3.1e-25
553482004841	HMMPfam hit to PF08242, Methyltransferase domain, score 6.9e-11
553482004842	Cupin domain; Region: Cupin_2; cl09118
553482004843	HMMPfam hit to PF07883, Cupin domain, score 6.5e-10
553482004844	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482004845	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482004846	active site
553482004847	phosphorylation site [posttranslational modification]
553482004848	intermolecular recognition site; other site
553482004849	dimerization interface [polypeptide binding]; other site
553482004850	LytTr DNA-binding domain; Region: LytTR; cl04498
553482004851	HMMPfam hit to PF00072, Response regulator receiver domain, score 0.00028
553482004852	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 1.4e-25
553482004853	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482004854	ABC-type multidrug transport system, ATPase component.  The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily.  ABC transporters are a large family of proteins involved in the...; Region: ABC_drug_resistance_like; cd03264
553482004855	Walker A/P-loop; other site
553482004856	ATP binding site [chemical binding]; other site
553482004857	Q-loop/lid; other site
553482004858	ABC transporter signature motif; other site
553482004859	Walker B; other site
553482004860	D-loop; other site
553482004861	H-loop/switch region; other site
553482004862	HMMPfam hit to PF00005, ABC transporter, score 4.1e-47
553482004863	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004864	PS00211 ABC transporters family signature.
553482004865	CDS is truncated by the insertion of the downstream IS element. Similar to the C-terminal region of Streptococcus agalactiae serotype III hypothetical protein GBS1941 UniProt:Q8E322 (EMBL:AL766854 (384 aa) fasta scores: E()=4.9e-60, 52.023% id in 346 aa
553482004866	5 transmembrane helices predicted for SEQ1098 by TMHMM2.0 at aa 17-39, 160-182, 207-229, 266-288 and 295-317
553482004867	putative transposase OrfB; Reviewed; Region: PHA02517
553482004868	HTH-like domain; Region: HTH_21; pfam13276
553482004869	Integrase core domain; Region: rve; cl01316
553482004870	Integrase core domain; Region: rve_3; cl15866
553482004871	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482004872	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004873	Helix-turn-helix domains; Region: HTH; cl00088
553482004874	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004875	HMMPfam hit to PF02178, no description, score 0.21
553482004876	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004877	CDS is truncated by the insertion of the upstream IS element
553482004878	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
553482004879	catalytic residues [active]
553482004880	catalytic nucleophile [active]
553482004881	Recombinase; Region: Recombinase; pfam07508
553482004882	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
553482004883	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 0.00042
553482004884	HMMPfam hit to PF07508, Recombinase, score 1.7e-22
553482004885	gene remnant. CDS is truncated by recombination event. N-terminal region of the this CDS is SEQ1276. Similar to the C-terminal region of Streptococcus suis ABC transporter permease UniProt:Q8VVF9 (EMBL:AJ416309 (257 aa) fasta scores: E()=1.2e-35, 71.939% id in 196 aa
553482004886	HMMPfam hit to PF00005, ABC transporter, score 3.9e-34
553482004887	PS00211 ABC transporters family signature.
553482004888	mevalonate kinase; Region: mevalon_kin; TIGR00549
553482004889	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482004890	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.2e-14
553482004891	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1.5e-12
553482004892	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
553482004893	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.5e-11
553482004894	PS00627 GHMP kinases ATP-binding domain.
553482004895	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1e-08
553482004896	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
553482004897	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482004898	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 2.5e-07
553482004899	HMMPfam hit to PF08544, GHMP kinases C terminal, score 9.8e-08
553482004900	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
553482004901	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
553482004902	homotetramer interface [polypeptide binding]; other site
553482004903	FMN binding site [chemical binding]; other site
553482004904	homodimer contacts [polypeptide binding]; other site
553482004905	putative active site [active]
553482004906	putative substrate binding site [chemical binding]; other site
553482004907	HMMPfam hit to PF01070, FMN-dependent dehydrogenase, score 2e-05
553482004908	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
553482004909	homodimer interface [polypeptide binding]; other site
553482004910	NAD binding site [chemical binding]; other site
553482004911	catalytic residues [active]
553482004912	substrate binding pocket [chemical binding]; other site
553482004913	flexible flap; other site
553482004914	'initiating' condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the...; Region: init_cond_enzymes; cd00827
553482004915	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
553482004916	dimer interface [polypeptide binding]; other site
553482004917	active site
553482004918	HMMPfam hit to PF08540, Hydroxymethylglutaryl-coenzyme A synth, score 1.9e-11
553482004919	HMMPfam hit to PF01154, Hydroxymethylglutaryl-coenzyme A synth, score 7.7e-08
553482004920	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
553482004921	dimerization interface [polypeptide binding]; other site
553482004922	active site
553482004923	HMMPfam hit to PF00303, Thymidylate synthase, score 4e-105
553482004924	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
553482004925	folate binding site [chemical binding]; other site
553482004926	NADP+ binding site [chemical binding]; other site
553482004927	HMMPfam hit to PF00186, Dihydrofolate reductase, score 1.1e-26
553482004928	PS00075 Dihydrofolate reductase signature.
553482004929	2 transmembrane helices predicted for SEQ1112 by TMHMM2.0 at aa 5-24 and 31-53
553482004930	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
553482004931	ClpX C4-type zinc finger; Region: zf-C4_ClpX; cl05964
553482004932	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482004933	Walker A motif; other site
553482004934	ATP binding site [chemical binding]; other site
553482004935	Walker B motif; other site
553482004936	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
553482004937	HMMPfam hit to PF06689, ClpX C4-type zinc finger, score 1.2e-23
553482004938	HMMPfam hit to PF07724, ATPase family associated with various cell, score 1.1e-80
553482004939	HMMPfam hit to PF00004, ATPase family associated with various cell, score 5.9e-06
553482004940	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004941	Predicted GTPase [General function prediction only]; Region: COG0218
553482004942	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
553482004943	G1 box; other site
553482004944	GTP/Mg2+ binding site [chemical binding]; other site
553482004945	Switch I region; other site
553482004946	G2 box; other site
553482004947	G3 box; other site
553482004948	Switch II region; other site
553482004949	G4 box; other site
553482004950	G5 box; other site
553482004951	HMMPfam hit to PF01926, GTPase of unknown function, score 5.2e-35
553482004952	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004953	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
553482004954	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
553482004955	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004956	1 transmembrane helix predicted for SEQ1116 by TMHMM2.0 at aa 974-991
553482004957	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482004958	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
553482004959	Walker A motif; other site
553482004960	ATP binding site [chemical binding]; other site
553482004961	Walker B motif; other site
553482004962	arginine finger; other site
553482004963	UvrB/uvrC motif; Region: UVR; pfam02151
553482004964	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482004965	Walker A motif; other site
553482004966	ATP binding site [chemical binding]; other site
553482004967	Walker B motif; other site
553482004968	arginine finger; other site
553482004969	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
553482004970	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 8.3e-05
553482004971	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 6.6e-77
553482004972	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004973	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.3e-12
553482004974	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004975	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
553482004976	active site
553482004977	multimer interface [polypeptide binding]; other site
553482004978	HMMPfam hit to PF00334, Nucleoside diphosphate kinase, score 3.5e-58
553482004979	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
553482004980	1 transmembrane helix predicted for SEQ1119 by TMHMM2.0 at aa 13-35
553482004981	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 3.6e-28
553482004982	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
553482004983	putative active site [active]
553482004984	putative metal binding site [ion binding]; other site
553482004985	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 1.5e-38
553482004986	1 transmembrane helix predicted for SEQ1120 by TMHMM2.0 at aa 13-35
553482004987	homoserine dehydrogenase; Provisional; Region: PRK06349
553482004988	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482004989	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
553482004990	HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 1.6e-24
553482004991	HMMPfam hit to PF00742, Homoserine dehydrogenase, score 3.2e-81
553482004992	PS01042 Homoserine dehydrogenase signature.
553482004993	homoserine kinase; Provisional; Region: PRK01212
553482004994	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482004995	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.2e-19
553482004996	PS00627 GHMP kinases ATP-binding domain.
553482004997	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1e-08
553482004998	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
553482004999	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482005000	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 0.021
553482005001	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
553482005002	homodecamer interface [polypeptide binding]; other site
553482005003	GTP cyclohydrolase I; Provisional; Region: PLN03044
553482005004	active site
553482005005	putative catalytic site residues [active]
553482005006	zinc binding site [ion binding]; other site
553482005007	GTP-CH-I/GFRP interaction surface; other site
553482005008	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 9.1e-54
553482005009	PS00859 GTP cyclohydrolase I signature 1.
553482005010	PS00860 GTP cyclohydrolase I signature 2.
553482005011	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
553482005012	dihydropteroate synthase; Region: DHPS; TIGR01496
553482005013	substrate binding pocket [chemical binding]; other site
553482005014	dimer interface [polypeptide binding]; other site
553482005015	inhibitor binding site; inhibition site
553482005016	PS00792 Dihydropteroate synthase signature 1.
553482005017	HMMPfam hit to PF00809, Pterin binding enzyme, score 5.2e-104
553482005018	PS00793 Dihydropteroate synthase signature 2.
553482005019	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
553482005020	homooctamer interface [polypeptide binding]; other site
553482005021	active site
553482005022	HMMPfam hit to PF02152, Dihydroneopterin aldolase, score 2.1e-43
553482005023	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
553482005024	catalytic center binding site [active]
553482005025	ATP binding site [chemical binding]; other site
553482005026	HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosph, score 2.4e-65
553482005027	PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
553482005028	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
553482005029	FAD binding domain; Region: FAD_binding_4; pfam01565
553482005030	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
553482005031	HMMPfam hit to PF01565, FAD binding domain, score 4.3e-34
553482005032	HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine red, score 2.3e-37
553482005033	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
553482005034	PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D.  PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required...; Region: ABC_PotA_N; cd03300
553482005035	Walker A/P-loop; other site
553482005036	ATP binding site [chemical binding]; other site
553482005037	Q-loop/lid; other site
553482005038	ABC transporter signature motif; other site
553482005039	Walker B; other site
553482005040	D-loop; other site
553482005041	H-loop/switch region; other site
553482005042	TOBE domain; Region: TOBE_2; cl01440
553482005043	HMMPfam hit to PF00005, ABC transporter, score 8.5e-65
553482005044	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005045	PS00211 ABC transporters family signature.
553482005046	HMMPfam hit to PF08402, TOBE domain, score 4.8e-08
553482005047	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
553482005048	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
553482005049	6 transmembrane helices predicted for SEQ1130 by TMHMM2.0 at aa 7-29, 61-83, 90-112, 139-161, 202-224 and 239-258
553482005050	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0039
553482005051	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482005052	dimer interface [polypeptide binding]; other site
553482005053	conserved gate region; other site
553482005054	putative PBP binding loops; other site
553482005055	ABC-ATPase subunit interface; other site
553482005056	7 transmembrane helices predicted for SEQ1131 by TMHMM2.0 at aa 7-29, 62-84, 97-119, 124-146, 174-193, 198-217 and 230-249
553482005057	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.4e-11
553482005058	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
553482005059	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482005060	1 transmembrane helix predicted for SEQ1132 by TMHMM2.0 at aa 5-24
553482005061	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.5e-15
553482005062	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005063	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
553482005064	Voltage gated chloride channel; Region: Voltage_CLC; pfam00654
553482005065	Cl- selectivity filter; other site
553482005066	Cl- binding residues [ion binding]; other site
553482005067	pore gating glutamate residue; other site
553482005068	dimer interface [polypeptide binding]; other site
553482005069	H+/Cl- coupling transport residue; other site
553482005070	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
553482005071	10 transmembrane helices predicted for SEQ1133 by TMHMM2.0 at aa 17-39, 59-78, 156-178, 191-213, 226-248, 268-288, 309-331, 335-354, 367-389 and 402-424
553482005072	HMMPfam hit to PF00654, Voltage gated chloride channel, score 4.1e-46
553482005073	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005074	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
553482005075	active site
553482005076	catalytic triad [active]
553482005077	oxyanion hole [active]
553482005078	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1.8e-07
553482005079	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; cl00465
553482005080	8 transmembrane helices predicted for SEQ1135 by TMHMM2.0 at aa 17-34, 49-68, 88-110, 180-202, 248-270, 274-296, 305-327 and 342-364
553482005081	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 1.2e-23
553482005082	hypothetical protein; Reviewed; Region: PRK00024
553482005083	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
553482005084	MPN+ (JAMM) motif; other site
553482005085	Zinc-binding site [ion binding]; other site
553482005086	HMMPfam hit to PF04002, RadC, DNA repair protein, score 7e-68
553482005087	PS01302 DNA repair protein radC family signature.
553482005088	Peptidase C26; Region: Peptidase_C26; pfam07722
553482005089	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
553482005090	catalytic triad [active]
553482005091	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.1e-05
553482005092	HMMPfam hit to PF07722, Peptidase C26, score 1.2e-100
553482005093	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
553482005094	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
553482005095	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005096	HMMPfam hit to PF02629, CoA binding domain, score 9.6e-33
553482005097	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005098	HMMPfam hit to PF06971, DNA-binding protein N-terminu, score 8.2e-28
553482005099	Predicted helix-turn-helix motif with score 1210.000, SD 3.31 at aa 33-54, sequence ASSKQIADAMGIDSATVRRDFS
553482005100	Putative amino acid metabolism; Region: DUF1831; pfam08866
553482005101	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
553482005102	cysteine desulfurase DndA; Region: DNA_S_dndA; TIGR03235
553482005103	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482005104	catalytic residue [active]
553482005105	HMMPfam hit to PF00266, Aminotransferase class-V, score 1.5e-86
553482005106	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005107	PS00729 AP endonucleases family 2 signature 1.
553482005108	HMMPfam hit to PF01212, Beta-eliminating lyase, score 7.8e-06
553482005109	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482005110	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02458
553482005111	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
553482005112	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482005113	active site
553482005114	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 3.4e-17
553482005115	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
553482005116	putative active site [active]
553482005117	putative metal binding residues [ion binding]; other site
553482005118	signature motif; other site
553482005119	putative triphosphate binding site [ion binding]; other site
553482005120	HMMPfam hit to PF01928, CYTH domain, score 2.6e-39
553482005121	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
553482005122	synthetase active site [active]
553482005123	NTP binding site [chemical binding]; other site
553482005124	metal binding site [ion binding]; metal-binding site
553482005125	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 9.6e-49
553482005126	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255
553482005127	HMMPfam hit to PF01513, ATP-NAD kinase, score 1.8e-41
553482005128	PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and...; Region: PseudoU_synth_RluCD_like; cd02869
553482005129	active site
553482005130	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 9.4e-51
553482005131	PS01129 Rlu family of pseudouridine synthase signature.
553482005132	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl00390
553482005133	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
553482005134	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 1.1e-163
553482005135	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
553482005136	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
553482005137	putative NAD(P) binding site [chemical binding]; other site
553482005138	homotetramer interface [polypeptide binding]; other site
553482005139	homodimer interface [polypeptide binding]; other site
553482005140	active site
553482005141	HMMPfam hit to PF00106, short chain dehydrogenase, score 4.5e-26
553482005142	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00042
553482005143	PS00061 Short-chain dehydrogenases/reductases family signature.
553482005144	CDS contains a nonsense mutation (achre) after codon 172. Similar to Streptococcus pyogenes serotype M3 ABC transporter Prot:Q8K7I8 (EMBL:AE014074 (242 aa) fasta scores: E()=9.3e-68, 87.190% id in 242 aa
553482005145	HMMPfam hit to PF00005, ABC transporter, score 2.2e-18
553482005146	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005147	PS00211 ABC transporters family signature.
553482005148	CDS contains a nonsense mutation (opal) after codon 198. Similar to Streptococcus pyogenes serotype M3 ABC transporter (binding protein) UniProt:Q8K7I7 (EMBL:AE014074 (508 aa) fasta scores: E()=5.7e-132, 81.102% id in 508 aa
553482005149	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-13
553482005150	5 transmembrane helices predicted for SEQ1151 by TMHMM2.0 at aa 23-45, 52-74, 78-97, 147-169 and 179-197
553482005151	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482005152	HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 1.5e-81
553482005153	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
553482005154	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine...; Region: IMPDH; cd00381
553482005155	active site
553482005156	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 1.9e-148
553482005157	Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins [Nucleotide transport and metabolism]; Region: Apt; COG0503
553482005158	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482005159	active site
553482005160	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.9e-17
553482005161	putative transposase OrfB; Reviewed; Region: PHA02517
553482005162	HTH-like domain; Region: HTH_21; pfam13276
553482005163	Integrase core domain; Region: rve; cl01316
553482005164	Integrase core domain; Region: rve_3; cl15866
553482005165	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482005166	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005167	Helix-turn-helix domains; Region: HTH; cl00088
553482005168	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005169	HMMPfam hit to PF02178, no description, score 0.21
553482005170	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005171	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
553482005172	active site 1 [active]
553482005173	dimer interface [polypeptide binding]; other site
553482005174	hexamer interface [polypeptide binding]; other site
553482005175	active site 2 [active]
553482005176	HMMPfam hit to PF01361, Tautomerase enzyme, score 4.4e-26
553482005177	thymidine kinase; Provisional; Region: PRK04296
553482005178	HMMPfam hit to PF00265, Thymidine kinase, score 3.5e-67
553482005179	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005180	PS00603 Thymidine kinase cellular-type signature.
553482005181	peptide chain release factor 1; Validated; Region: prfA; PRK00591
553482005182	RF-1 domain; Region: RF-1; cl02875
553482005183	RF-1 domain; Region: RF-1; cl02875
553482005184	HMMPfam hit to PF03462, PCRF domain, score 2e-64
553482005185	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 9.5e-61
553482005186	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
553482005187	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482005188	S-adenosylmethionine binding site [chemical binding]; other site
553482005189	HMMPfam hit to PF05175, Methyltransferase small domain, score 5.9e-11
553482005190	HMMPfam hit to PF08242, Methyltransferase domain, score 4.6e-06
553482005191	HMMPfam hit to PF08241, Methyltransferase domain, score 0.00021
553482005192	PS00092 N-6 Adenine-specific DNA methylases signature.
553482005193	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
553482005194	HMMPfam hit to PF01300, yrdC domain, score 1.5e-37
553482005195	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
553482005196	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482005197	Coenzyme A binding pocket [chemical binding]; other site
553482005198	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.4e-12
553482005199	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
553482005200	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
553482005201	dimer interface [polypeptide binding]; other site
553482005202	glycine-pyridoxal phosphate binding site [chemical binding]; other site
553482005203	active site
553482005204	folate binding site [chemical binding]; other site
553482005205	HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 1.3e-229
553482005206	PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
553482005207	37-kD nucleoid-associated bacterial protein; Region: NA37; cl15473
553482005208	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482005209	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
553482005210	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482005211	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482005212	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.9e-45
553482005213	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005214	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.9e-32
553482005215	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 3.3e-07
553482005216	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
553482005217	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
553482005218	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482005219	NAD binding site [chemical binding]; other site
553482005220	dimer interface [polypeptide binding]; other site
553482005221	substrate binding site [chemical binding]; other site
553482005222	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 3.1e-77
553482005223	PS00064 L-lactate dehydrogenase active site.
553482005224	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 3.2e-78
553482005225	DNA gyrase subunit A; Validated; Region: PRK05560
553482005226	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA...; Region: TOP4c; cd00187
553482005227	CAP-like domain; other site
553482005228	active site
553482005229	primary dimer interface [polypeptide binding]; other site
553482005230	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005231	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005232	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005233	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005234	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005235	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005236	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 8e-304
553482005237	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.5e-13
553482005238	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.9e-17
553482005239	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 5.2e-14
553482005240	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.8e-13
553482005241	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.9e-14
553482005242	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 4.5e-12
553482005243	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
553482005244	active site
553482005245	catalytic site [active]
553482005246	1 transmembrane helix predicted for SEQ1171 by TMHMM2.0 at aa 4-21
553482005247	HMMPfam hit to PF04203, Sortase family, score 5.8e-55
553482005248	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
553482005249	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
553482005250	putative metal binding site [ion binding]; other site
553482005251	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 5.2e-19
553482005252	PS00934 Glyoxalase I signature 1.
553482005253	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482005254	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
553482005255	intersubunit interface [polypeptide binding]; other site
553482005256	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 4.9e-76
553482005257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005258	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482005259	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
553482005260	HMMPfam hit to PF06207, Protein of unknown function (DUF1002), score 4.5e-99
553482005261	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482005262	HMMPfam hit to PF02388, FemAB family, score 7.7e-20
553482005263	signal recognition particle protein; Provisional; Region: PRK10867
553482005264	SRP54-type protein, helical bundle domain; Region: SRP54_N; cl03758
553482005265	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
553482005266	P loop; other site
553482005267	GTP binding site [chemical binding]; other site
553482005268	Signal peptide binding domain; Region: SRP_SPB; pfam02978
553482005269	HMMPfam hit to PF02978, Signal peptide binding domain, score 8.4e-55
553482005270	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 5.4e-119
553482005271	PS00300 SRP54-type proteins GTP-binding domain signature.
553482005272	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005273	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 1.1e-31
553482005274	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482005275	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
553482005276	HMMPfam hit to PF04297, helix-turn-helix protein, YlxM, score 3.5e-60
553482005277	HMMPfam hit to PF04967, HTH DNA binding domain, score 0.00014
553482005278	HMMPfam hit to PF08281, Sigma-70, region, score 6.6e-05
553482005279	Predicted helix-turn-helix motif with score 1959.000, SD 5.86 at aa 36-57, sequence YSLAEIAEEFGVSRQAVYDNIK
553482005280	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482005281	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482005282	DNA-binding site [nucleotide binding]; DNA binding site
553482005283	UTRA domain; Region: UTRA; cl01230
553482005284	HMMPfam hit to PF07702, UTRA domain, score 1.2e-46
553482005285	Predicted helix-turn-helix motif with score 1149.000, SD 3.10 at aa 161-182, sequence QTLTSNGYEIGKSQQTIYAKIA
553482005286	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.9e-23
553482005287	PS00043 Bacterial regulatory proteins, gntR family signature.
553482005288	Predicted helix-turn-helix motif with score 1494.000, SD 4.28 at aa 28-49, sequence PSERDLAEHFEVSRMTLRQAIT
553482005289	GMP synthase; Reviewed; Region: guaA; PRK00074
553482005290	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
553482005291	AMP/PPi binding site [chemical binding]; other site
553482005292	candidate oxyanion hole; other site
553482005293	catalytic triad [active]
553482005294	potential glutamine specificity residues [chemical binding]; other site
553482005295	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
553482005296	ATP Binding subdomain [chemical binding]; other site
553482005297	Dimerization subdomain; other site
553482005298	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.5e-55
553482005299	PS00442 Glutamine amidotransferases class-I active site.
553482005300	HMMPfam hit to PF00958, GMP synthase C terminal domain, score 5e-55
553482005301	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482005302	non-specific DNA binding site [nucleotide binding]; other site
553482005303	salt bridge; other site
553482005304	sequence-specific DNA binding site [nucleotide binding]; other site
553482005305	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482005306	Catalytic site [active]
553482005307	HMMPfam hit to PF00717, Peptidase S24-like, score 1.9e-17
553482005308	HMMPfam hit to PF01381, Helix-turn-helix, score 3.5e-12
553482005309	Predicted helix-turn-helix motif with score 2505.000, SD 7.72 at aa 18-39, sequence ISQEQLGQLLGVNKMTISNWEK
553482005310	GtrA-like protein; Region: GtrA; cl00971
553482005311	4 transmembrane helices predicted for SEQ1185 by TMHMM2.0 at aa 7-29, 34-56, 77-96 and 120-139
553482005312	HMMPfam hit to PF04138, GtrA-like protein, score 5.3e-15
553482005313	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
553482005314	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
553482005315	DNA binding site [nucleotide binding]
553482005316	Int/Topo IB signature motif; other site
553482005317	active site
553482005318	HMMPfam hit to PF00589, Phage integrase family, score 4.6e-13
553482005319	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482005320	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482005321	ATP binding site [chemical binding]; other site
553482005322	Mg2+ binding site [ion binding]; other site
553482005323	G-X-G motif; other site
553482005324	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9e-26
553482005325	2 transmembrane helices predicted for SEQ1187 by TMHMM2.0 at aa 9-31 and 35-57
553482005326	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482005327	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482005328	active site
553482005329	phosphorylation site [posttranslational modification]
553482005330	intermolecular recognition site; other site
553482005331	dimerization interface [polypeptide binding]; other site
553482005332	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482005333	DNA binding site [nucleotide binding]
553482005334	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.1e-20
553482005335	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482005336	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-19
553482005337	2 transmembrane helices predicted for SEQ1189 by TMHMM2.0 at aa 47-69 and 84-106
553482005338	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005339	Helix-turn-helix domains; Region: HTH; cl00088
553482005340	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005341	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005342	HMMPfam hit to PF02178, no description, score 0.21
553482005343	putative transposase OrfB; Reviewed; Region: PHA02517
553482005344	HTH-like domain; Region: HTH_21; pfam13276
553482005345	Integrase core domain; Region: rve; cl01316
553482005346	Integrase core domain; Region: rve_3; cl15866
553482005347	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005348	7 transmembrane helices predicted for SEQ1192 by TMHMM2.0 at aa 21-43, 53-75, 105-127, 147-169, 190-212, 222-244 and 280-302
553482005349	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482005350	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482005351	Walker A/P-loop; other site
553482005352	ATP binding site [chemical binding]; other site
553482005353	Q-loop/lid; other site
553482005354	ABC transporter signature motif; other site
553482005355	Walker B; other site
553482005356	D-loop; other site
553482005357	H-loop/switch region; other site
553482005358	HMMPfam hit to PF00005, ABC transporter, score 2.1e-62
553482005359	PS00211 ABC transporters family signature.
553482005360	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005361	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
553482005362	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482005363	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482005364	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482005365	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482005366	oxaloacetate decarboxylase; Provisional; Region: PRK12331
553482005367	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
553482005368	active site
553482005369	catalytic residues [active]
553482005370	metal binding site [ion binding]; metal-binding site
553482005371	homodimer binding site [polypeptide binding]; other site
553482005372	HMMPfam hit to PF02436, Conserved carboxylase domain, score 2.3e-58
553482005373	HMMPfam hit to PF00682, HMGL-like, score 2.1e-46
553482005374	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
553482005375	HMMPfam hit to PF03802, Apo-citrate lyase phosphoribosyl-dephospho-C, score 6.7e-79
553482005376	Citrate lyase, alpha subunit (CitF); Region: CitF; pfam04223
553482005377	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482005378	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482005379	HMMPfam hit to PF04223, Citrate lyase, alpha subunit (CitF), score 0
553482005380	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl09155
553482005381	HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 2.1e-118
553482005382	Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082
553482005383	HMMPfam hit to PF04953, Citrate lyase, gamma subunit, score 8.2e-63
553482005384	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; cl01458
553482005385	1 transmembrane helix predicted for SEQ1202 by TMHMM2.0 at aa 13-35
553482005386	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
553482005387	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacet, score 8.5e-263
553482005388	9 transmembrane helices predicted for SEQ1203 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 105-127, 134-156, 166-187, 208-230, 281-303 and 345-367
553482005389	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
553482005390	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
553482005391	carboxyltransferase (CT) interaction site; other site
553482005392	biotinylation site [posttranslational modification]; other site
553482005393	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 4.5e-25
553482005394	PS00188 Biotin-requiring enzymes attachment site.
553482005395	C4-dicarboxylate anaerobic carrier; Region: DcuC; cl15356
553482005396	Citrate transporter; Region: CitMHS; pfam03600
553482005397	13 transmembrane helices predicted for SEQ1206 by TMHMM2.0 at aa 2-19, 24-46, 85-107, 122-153, 160-182, 197-219, 258-275, 280-299, 319-341, 356-375, 382-404, 409-431 and 443-465
553482005398	HMMPfam hit to PF03600, Citrate transporter, score 1.3e-136
553482005399	PS00211 ABC transporters family signature.
553482005400	Transcriptional regulators [Transcription]; Region: GntR; COG1802
553482005401	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482005402	DNA-binding site [nucleotide binding]; DNA binding site
553482005403	FCD domain; Region: FCD; cl11656
553482005404	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 9.8e-07
553482005405	Predicted helix-turn-helix motif with score 1180.000, SD 3.21 at aa 43-64, sequence INEKEFSIALNISRTPIRYALG
553482005406	HMMPfam hit to PF07729, FCD domain, score 8.1e-05
553482005407	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
553482005408	HMMPfam hit to PF01874, ATP:dephospho-CoA triphosphoribosyl transfer, score 5.8e-61
553482005409	PS00881 Protein splicing signature.
553482005410	CDS contains a frameshift at a polyA pentamer
553482005411	3 transmembrane helices predicted for SEQ1209 by TMHMM2.0 at aa 4-26, 63-85 and 125-147
553482005412	3 transmembrane helices predicted for SEQ1210 by TMHMM2.0 at aa 20-42, 82-104 and 137-159
553482005413	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
553482005414	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482005415	active site
553482005416	nucleotide binding site [chemical binding]; other site
553482005417	HIGH motif; other site
553482005418	KMSKS motif; other site
553482005419	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.1e-05
553482005420	HMMPfam hit to PF08218, Citrate lyase ligase C-terminal domain, score 1.8e-99
553482005421	putative transposase OrfB; Reviewed; Region: PHA02517
553482005422	HTH-like domain; Region: HTH_21; pfam13276
553482005423	Integrase core domain; Region: rve; cl01316
553482005424	Integrase core domain; Region: rve_3; cl15866
553482005425	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005426	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005427	Helix-turn-helix domains; Region: HTH; cl00088
553482005428	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005429	HMMPfam hit to PF02178, no description, score 0.21
553482005430	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005431	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482005432	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482005433	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482005434	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482005435	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
553482005436	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005437	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 3.5e-184
553482005438	PS01281 Glucose inhibited division protein A family signature 2.
553482005439	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
553482005440	5 transmembrane helices predicted for SEQ1217 by TMHMM2.0 at aa 52-74, 95-114, 129-151, 178-197 and 212-234
553482005441	DNA topoisomerase I; Validated; Region: PRK05582
553482005442	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
553482005443	active site
553482005444	interdomain interaction site; other site
553482005445	putative metal-binding site [ion binding]; other site
553482005446	nucleotide binding site [chemical binding]; other site
553482005447	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
553482005448	domain I; other site
553482005449	DNA binding groove [nucleotide binding]
553482005450	phosphate binding site [ion binding]; other site
553482005451	domain II; other site
553482005452	domain III; other site
553482005453	nucleotide binding site [chemical binding]; other site
553482005454	catalytic site [active]
553482005455	domain IV; other site
553482005456	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
553482005457	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
553482005458	HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 3.8e-14
553482005459	HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 2.1e-15
553482005460	HMMPfam hit to PF01131, DNA topoisomerase, score 6.4e-170
553482005461	PS00396 Prokaryotic DNA topoisomerase I active site.
553482005462	HMMPfam hit to PF01751, Toprim domain, score 1.5e-33
553482005463	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
553482005464	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
553482005465	HMMPfam hit to PF02481, SMF family, score 6.3e-83
553482005466	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
553482005467	RNA/DNA hybrid binding site [nucleotide binding]; other site
553482005468	active site
553482005469	HMMPfam hit to PF01351, Ribonuclease HII, score 1.2e-71
553482005470	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005471	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
553482005472	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
553482005473	GTP/Mg2+ binding site [chemical binding]; other site
553482005474	G4 box; other site
553482005475	G5 box; other site
553482005476	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005477	G1 box; other site
553482005478	G1 box; other site
553482005479	GTP/Mg2+ binding site [chemical binding]; other site
553482005480	Switch I region; other site
553482005481	G2 box; other site
553482005482	G2 box; other site
553482005483	G3 box; other site
553482005484	G3 box; other site
553482005485	Switch II region; other site
553482005486	Switch II region; other site
553482005487	G4 box; other site
553482005488	G5 box; other site
553482005489	HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-19
553482005490	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005491	CDS contains a nonsense mutation (amber) after codon 138. Similar to Streptococcus pneumoniae ABC transporter, ATP-binding protein UniProt:Q97NR1 (EMBL:AE005672 (210 aa) fasta scores: E()=1.7e-55, 89.048% id in 210 aa
553482005492	Predicted helix-turn-helix motif with score 1005.000, SD 2.61 at aa 96-117, sequence LKLGLIGQKLNKSEQTMRQKQA
553482005493	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005494	gene remnant. Similar to the C-terminal region of Streptococcus pneumoniae hypothetical protein UniProt:Q9ZHB2 (EMBL:AF068902 (493 aa) fasta scores: E()=1.1e-36, 42.014% id in 288 aa
553482005495	HMMPfam hit to PF07242, Protein of unknown function (DUF1430), score 1.2e-43
553482005496	3 transmembrane helices predicted for SEQ1225 by TMHMM2.0 at aa 185-207, 227-249 and 253-273
553482005497	gene remnant; Similar to internal region of S. zooepidemicus protein SZO09950
553482005498	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005499	Helix-turn-helix domains; Region: HTH; cl00088
553482005500	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005501	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005502	HMMPfam hit to PF02178, no description, score 0.21
553482005503	putative transposase OrfB; Reviewed; Region: PHA02517
553482005504	HTH-like domain; Region: HTH_21; pfam13276
553482005505	Integrase core domain; Region: rve; cl01316
553482005506	Integrase core domain; Region: rve_3; cl15866
553482005507	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005508	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
553482005509	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
553482005510	catalytic residues [active]
553482005511	catalytic nucleophile [active]
553482005512	Recombinase; Region: Recombinase; pfam07508
553482005513	HMMPfam hit to PF07508, Recombinase, score 1.1e-16
553482005514	ICESe2
553482005515	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005516	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 0.00013
553482005517	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; Region: RpoD; COG0568
553482005518	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482005519	DNA binding residues [nucleotide binding]
553482005520	HMMPfam hit to PF04545, Sigma-70, region, score 5.8e-08
553482005521	HMMPfam hit to PF08281, Sigma-70, region, score 0.0027
553482005522	Predicted helix-turn-helix motif with score 1283.000, SD 3.56 at aa 100-121, sequence KTLTEVAKQRDTNPMKISRLRN
553482005523	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005524	Q-loop/lid; other site
553482005525	ABC transporter signature motif; other site
553482005526	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
553482005527	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482005528	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482005529	PS00120 Lipases, serine active site.
553482005530	1 transmembrane helix predicted for SEQ1233 by TMHMM2.0 at aa 5-27
553482005531	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
553482005532	HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 0.00022
553482005533	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005534	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482005535	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005536	Walker A/P-loop; other site
553482005537	ATP binding site [chemical binding]; other site
553482005538	Q-loop/lid; other site
553482005539	ABC transporter signature motif; other site
553482005540	Walker B; other site
553482005541	D-loop; other site
553482005542	H-loop/switch region; other site
553482005543	HMMPfam hit to PF00005, ABC transporter, score 5.3e-59
553482005544	PS00211 ABC transporters family signature.
553482005545	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005546	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2e-05
553482005547	6 transmembrane helices predicted for SEQ1235 by TMHMM2.0 at aa 21-43, 63-85, 143-161, 165-183, 251-273 and 277-296
553482005548	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005549	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482005550	MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins.  ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic...; Region: ABCC_MsbA; cd03251
553482005551	Walker A/P-loop; other site
553482005552	ATP binding site [chemical binding]; other site
553482005553	Q-loop/lid; other site
553482005554	ABC transporter signature motif; other site
553482005555	Walker B; other site
553482005556	D-loop; other site
553482005557	H-loop/switch region; other site
553482005558	HMMPfam hit to PF00005, ABC transporter, score 1.1e-57
553482005559	PS00211 ABC transporters family signature.
553482005560	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005561	5 transmembrane helices predicted for SEQ1236 by TMHMM2.0 at aa 21-43, 58-80, 142-164, 250-272 and 279-296
553482005562	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.8e-12
553482005563	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
553482005564	Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota.  The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed.  This ABC...; Region: ABC_cobalt_CbiO_domain1; cd03225
553482005565	Walker A/P-loop; other site
553482005566	ATP binding site [chemical binding]; other site
553482005567	Q-loop/lid; other site
553482005568	ABC transporter signature motif; other site
553482005569	Walker B; other site
553482005570	D-loop; other site
553482005571	H-loop/switch region; other site
553482005572	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005573	Walker A/P-loop; other site
553482005574	ATP binding site [chemical binding]; other site
553482005575	Q-loop/lid; other site
553482005576	ABC transporter signature motif; other site
553482005577	Walker B; other site
553482005578	D-loop; other site
553482005579	H-loop/switch region; other site
553482005580	HMMPfam hit to PF00005, ABC transporter, score 1.8e-41
553482005581	PS00211 ABC transporters family signature.
553482005582	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005583	HMMPfam hit to PF00005, ABC transporter, score 6.2e-39
553482005584	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005585	Cobalt transport protein; Region: CbiQ; cl00463
553482005586	HMMPfam hit to PF02361, Cobalt transport protein, score 0.00031
553482005587	3 transmembrane helices predicted for SEQ1238 by TMHMM2.0 at aa 15-37, 49-71 and 81-103
553482005588	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; cl09823
553482005589	6 transmembrane helices predicted for SEQ1239 by TMHMM2.0 at aa 12-29, 33-55, 62-79, 84-103, 110-132 and 159-181
553482005590	Condensation domain; Region: Condensation; pfam00668
553482005591	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005592	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005593	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005594	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482005595	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 0.00013
553482005596	HMMPfam hit to PF08241, Methyltransferase domain, score 0.0019
553482005597	HMMPfam hit to PF08242, Methyltransferase domain, score 8.6e-10
553482005598	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 5.4e-06
553482005599	HMMPfam hit to PF00668, Condensation domain, score 2e-12
553482005600	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
553482005601	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482005603	S-adenosylmethionine binding site [chemical binding]; other site
553482005604	HMMPfam hit to PF08241, Methyltransferase domain, score 6.5e-07
553482005605	HMMPfam hit to PF08242, Methyltransferase domain, score 1.2e-18
553482005606	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ro, score 1.3e-22
553482005607	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482005608	Condensation domain; Region: Condensation; pfam00668
553482005609	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005610	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005611	AMP-binding enzyme; Region: AMP-binding; cl15778
553482005612	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005613	peptide synthase; Provisional; Region: PRK12467
553482005614	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482005615	Condensation domain; Region: Condensation; pfam00668
553482005616	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005617	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005618	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482005619	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.7e-10
553482005620	PS00012 Phosphopantetheine attachment site.
553482005621	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 5e-16
553482005622	HMMPfam hit to PF00668, Condensation domain, score 1.3e-33
553482005623	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.8e-10
553482005624	PS00455 AMP-binding domain signature.
553482005625	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.1e-14
553482005626	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005627	HMMPfam hit to PF00668, Condensation domain, score 4.5e-43
553482005628	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
553482005629	AMP-binding enzyme; Region: AMP-binding; cl15778
553482005630	HMMPfam hit to PF00501, AMP-binding enzyme, score 2.2e-86
553482005631	PS00455 AMP-binding domain signature.
553482005632	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
553482005633	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
553482005634	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 8.5e-06
553482005635	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
553482005636	HMMPfam hit to PF00975, Thioesterase domain, score 7.2e-43
553482005637	Helix-turn-helix domains; Region: HTH; cl00088
553482005638	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
553482005639	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
553482005640	HMMPfam hit to PF01047, MarR family, score 0.0022
553482005641	HMMPfam hit to PF01325, Iron dependent repressor, N-terminal D, score 4.8e-07
553482005642	Predicted helix-turn-helix motif with score 1163.000, SD 3.15 at aa 28-49, sequence VRNIDIVDKLGVARATVTHMLR
553482005643	1 transmembrane helix predicted for SEQ1247 by TMHMM2.0 at aa 20-42
553482005644	Relaxase/Mobilisation nuclease domain; Region: Relaxase; cl01584
553482005645	HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 5.6e-44
553482005646	4 transmembrane helices predicted for SEQ1251 by TMHMM2.0 at aa 5-27, 58-80, 93-115 and 130-148
553482005647	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
553482005648	generic binding surface II; other site
553482005649	generic binding surface I; other site
553482005650	HMMPfam hit to PF00436, Single-strand binding protein family, score 0.0087
553482005651	Uncharacterized conserved protein [Function unknown]; Region: COG4983
553482005652	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005653	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005654	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482005655	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005656	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005657	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0011
553482005658	HMMPfam hit to PF02384, N-6 DNA Methylase, score 0.00028
553482005659	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482005660	PS00092 N-6 Adenine-specific DNA methylases signature.
553482005661	DNA topoisomerase III; Provisional; Region: PRK07726
553482005662	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
553482005663	active site
553482005664	putative interdomain interaction site [polypeptide binding]; other site
553482005665	putative metal-binding site [ion binding]; other site
553482005666	putative nucleotide binding site [chemical binding]; other site
553482005667	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
553482005668	domain I; other site
553482005669	DNA binding groove [nucleotide binding]
553482005670	phosphate binding site [ion binding]; other site
553482005671	domain II; other site
553482005672	domain III; other site
553482005673	nucleotide binding site [chemical binding]; other site
553482005674	catalytic site [active]
553482005675	domain IV; other site
553482005676	HMMPfam hit to PF01131, DNA topoisomerase, score 2.7e-95
553482005677	PS00396 Prokaryotic DNA topoisomerase I active site.
553482005678	HMMPfam hit to PF01751, Toprim domain, score 2.7e-21
553482005679	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; cl00973
553482005680	Predicted helix-turn-helix motif with score 1063.000, SD 2.81 at aa 228-249, sequence GKIIDLLEKLKINEAFLKRWQA
553482005681	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
553482005682	Domain of unknown function (DUF4404); Region: DUF4404; pfam14357
553482005683	Domain of unknown function (DUF4366); Region: DUF4366; pfam14283
553482005684	2 transmembrane helices predicted for SEQ1259 by TMHMM2.0 at aa 5-27 and 453-475
553482005685	1 transmembrane helix predicted for SEQ1261 by TMHMM2.0 at aa 415-437
553482005686	PS00018 EF-hand calcium-binding domain.
553482005687	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005688	HMMPfam hit to PF01555, DNA methylase, score 1.1e-67
553482005689	PS00093 N-4 cytosine-specific DNA methylases signature.
553482005690	AAA-like domain; Region: AAA_10; pfam12846
553482005691	Predicted helix-turn-helix motif with score 1355.000, SD 3.80 at aa 744-765, sequence TDRDILAKKLNISKHQLSYVTN
553482005692	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005693	PrgI family protein; Region: PrgI; pfam12666
553482005694	2 transmembrane helices predicted for SEQ1264 by TMHMM2.0 at aa 26-43 and 47-69
553482005695	1 transmembrane helix predicted for SEQ1265 by TMHMM2.0 at aa 13-32
553482005696	5 transmembrane helices predicted for SEQ1266 by TMHMM2.0 at aa 49-71, 92-109, 168-190, 210-232 and 242-264
553482005697	Maff2 family; Region: Maff2; pfam12750
553482005698	2 transmembrane helices predicted for SEQ1267 by TMHMM2.0 at aa 7-28 and 48-70
553482005699	1 transmembrane helix predicted for SEQ1268 by TMHMM2.0 at aa 5-24
553482005700	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482005701	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482005702	Walker A/P-loop; other site
553482005703	ATP binding site [chemical binding]; other site
553482005704	Q-loop/lid; other site
553482005705	ABC transporter signature motif; other site
553482005706	Walker B; other site
553482005707	D-loop; other site
553482005708	H-loop/switch region; other site
553482005709	HMMPfam hit to PF00005, ABC transporter, score 5.9e-43
553482005710	PS00211 ABC transporters family signature.
553482005711	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005712	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
553482005713	8 transmembrane helices predicted for SEQ1270 by TMHMM2.0 at aa 7-29, 188-210, 236-258, 273-295, 316-338, 593-611, 648-670 and 685-707
553482005714	Bacteriocin (Lactococcin_972); Region: Lactococcin_972; cl09891
553482005715	gene remnant. Similar to the C-terminal region of Enterococcus faecalis VanSG UniProt:Q9KHM2 (EMBL:AF253562 (367 aa) fasta scores: E()=3.5e-12, 31.841% id in 201 aa
553482005716	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.2e-12
553482005717	Similar to the N-terminal region of Geobacter uraniumreducens RF4 hypothetical protein UniProt:Q2DIN1 (EMBL:AAON01000083 (285 aa) fasta scores: E()=4.2e-39, 55.251% id in 219 aa. CDS is truncated by the insertion of the downstream conjugative transposon and IS element
553482005718	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
553482005719	ParB-like nuclease domain; Region: ParBc; cl02129
553482005720	Predicted helix-turn-helix motif with score 1106.000, SD 2.95 at aa 176-197, sequence DSRKTLGKEYNLSGASIARYLR
553482005721	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.6e-15
553482005722	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
553482005723	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
553482005724	P-loop; other site
553482005725	Magnesium ion binding site [ion binding]; other site
553482005726	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
553482005727	Magnesium ion binding site [ion binding]; other site
553482005728	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.8e-52
553482005729	gene remnant. CDS is truncated by recombination event. C-terminal region of the this CDS is SEQ1103. Similar to the N-terminal region of bacillus thuringiensis serovar israelensis multidrug/protein/lipid ABC transporter family, ATP-binding permease protein UniProt:Q3ER17 (EMBL:AAJM01000217 (588 aa) fasta scores: E()=9.9e-30, 30.179% id in 391 aa
553482005730	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.7e-20
553482005731	4 transmembrane helices predicted for SEQ1276 by TMHMM2.0 at aa 13-35, 64-83, 139-161 and 166-183
553482005732	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005733	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482005734	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005735	Walker A/P-loop; other site
553482005736	ATP binding site [chemical binding]; other site
553482005737	Q-loop/lid; other site
553482005738	ABC transporter signature motif; other site
553482005739	Walker B; other site
553482005740	D-loop; other site
553482005741	H-loop/switch region; other site
553482005742	HMMPfam hit to PF00005, ABC transporter, score 4.7e-54
553482005743	PS00211 ABC transporters family signature.
553482005744	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005745	6 transmembrane helices predicted for SEQ1277 by TMHMM2.0 at aa 13-35, 55-77, 124-146, 151-173, 239-261 and 276-298
553482005746	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.2e-21
553482005747	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
553482005748	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
553482005749	putative active site [active]
553482005750	putative metal binding site [ion binding]; other site
553482005751	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
553482005752	1 transmembrane helix predicted for SEQ1278 by TMHMM2.0 at aa 5-27
553482005753	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 6e-09
553482005754	PS00786 5'-nucleotidase signature 2.
553482005755	HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 9e-49
553482005756	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482005757	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
553482005758	active site
553482005759	catalytic residues [active]
553482005760	metal binding site [ion binding]; metal-binding site
553482005761	HMMPfam hit to PF01327, Polypeptide deformylase, score 5.3e-11
553482005762	glutamate dehydrogenase; Provisional; Region: PRK09414
553482005763	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
553482005764	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
553482005765	NAD(P) binding site [chemical binding]; other site
553482005766	HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 3.4e-132
553482005767	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005768	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 4.8e-85
553482005769	CDS contains a frameshift after codon 288, due to the insertion of 4 nucleotides. Similar to Streptococcus agalactiae ABC transporter, ATP-binding/permease protein UniProt:Q3D0Y9 (EMBL:AAJS01000036 (589 aa) fasta scores: E()=4.1e-132, 76.061% id in 589 aa
553482005770	HMMPfam hit to PF00005, ABC transporter, score 3.5e-60
553482005771	PS00211 ABC transporters family signature.
553482005772	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005773	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
553482005774	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.6e-34
553482005775	5 transmembrane helices predicted for SEQ1282 by TMHMM2.0 at aa 20-42, 62-84, 152-169, 173-192 and 260-282
553482005776	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005777	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482005778	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482005779	Walker A/P-loop; other site
553482005780	ATP binding site [chemical binding]; other site
553482005781	Q-loop/lid; other site
553482005782	ABC transporter signature motif; other site
553482005783	Walker B; other site
553482005784	D-loop; other site
553482005785	H-loop/switch region; other site
553482005786	HMMPfam hit to PF00005, ABC transporter, score 5e-52
553482005787	PS00211 ABC transporters family signature.
553482005788	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005789	6 transmembrane helices predicted for SEQ1283 by TMHMM2.0 at aa 20-37, 52-74, 129-151, 156-175, 237-259 and 274-296
553482005790	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 5.4e-30
553482005791	CDS contains a frameshift after codon 442. Frameshift occurs at a poly A hexamer. Similar to Streptococcus pyogenes serotype M3 ABC transporter ATP-binding protein Uup UniProt:Q1JHD9 (EMBL:CP000260 (625 aa) fasta scores: E()=3.2e-115, 78.115% id in 626 aa
553482005792	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005793	HMMPfam hit to PF00005, ABC transporter, score 5.8e-39
553482005794	PS00211 ABC transporters family signature.
553482005795	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005796	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
553482005797	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
553482005798	active site
553482005799	NTP binding site [chemical binding]; other site
553482005800	metal binding triad [ion binding]; metal-binding site
553482005801	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
553482005802	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482005803	HMMPfam hit to PF01743, Poly A polymerase family, score 5e-58
553482005804	Uncharacterized protein, DegV family COG1307; Region: DegV; cl00577
553482005805	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 1e-76
553482005806	Protein of unknown function (DUF1149); Region: DUF1149; cl11551
553482005807	HMMPfam hit to PF06619, Protein of unknown function (DUF1149), score 5.8e-95
553482005808	putative transposase OrfB; Reviewed; Region: PHA02517
553482005809	HTH-like domain; Region: HTH_21; pfam13276
553482005810	Integrase core domain; Region: rve; cl01316
553482005811	Integrase core domain; Region: rve_3; cl15866
553482005812	HMMPfam hit to PF00665, Integrase core domain, score 5.4e-39
553482005813	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005814	Helix-turn-helix domains; Region: HTH; cl00088
553482005815	HMMPfam hit to PF01527, Transposase, score 0.00051
553482005816	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482005817	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.5e-36
553482005818	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005819	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15357
553482005820	transmembrane helices; other site
553482005821	HMMPfam hit to PF00939, Sodium:sulfate symporter transmembrane, score 3e-06
553482005822	12 transmembrane helices predicted for SEQ1292 by TMHMM2.0 at aa 12-29, 39-61, 74-96, 125-147, 168-187, 207-229, 257-274, 279-298, 311-333, 353-375, 395-417 and 427-449
553482005823	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005824	4 transmembrane helices predicted for SEQ1295 by TMHMM2.0 at aa 5-23, 38-60, 85-107 and 111-133
553482005825	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005826	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482005827	non-specific DNA binding site [nucleotide binding]; other site
553482005828	salt bridge; other site
553482005829	sequence-specific DNA binding site [nucleotide binding]; other site
553482005830	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-17
553482005831	Predicted helix-turn-helix motif with score 1884.000, SD 5.60 at aa 14-35, sequence ITQEELASILEVSRQTIGSLEN
553482005832	Transposase IS200 like; Region: Y1_Tnp; cl00848
553482005833	HMMPfam hit to PF01797, Transposase IS200 like, score 1.3e-54
553482005834	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482005835	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 8.7e-27
553482005836	1 transmembrane helix predicted for SEQ1298 by TMHMM2.0 at aa 21-40
553482005837	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482005838	active site
553482005839	phosphorylation site [posttranslational modification]
553482005840	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
553482005841	P-loop; other site
553482005842	active site
553482005843	phosphorylation site [posttranslational modification]
553482005844	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482005845	10 transmembrane helices predicted for SEQ1299 by TMHMM2.0 at aa 295-317, 338-360, 370-392, 399-421, 441-462, 474-496, 524-546, 558-580, 595-617 and 624-643
553482005846	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3.6e-14
553482005847	PS00044 Bacterial regulatory proteins, lysR family signature.
553482005848	PS00583 pfkB family of carbohydrate kinases signature 1.
553482005849	HMMPfam hit to PF02379, PTS system, Fructose specific IIB subuni, score 1.7e-51
553482005850	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phos, score 8.9e-25
553482005851	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
553482005852	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
553482005853	putative substrate binding site [chemical binding]; other site
553482005854	putative ATP binding site [chemical binding]; other site
553482005855	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.3e-56
553482005856	PS00584 pfkB family of carbohydrate kinases signature 2.
553482005857	PS00583 pfkB family of carbohydrate kinases signature 1.
553482005858	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482005859	Helix-turn-helix domains; Region: HTH; cl00088
553482005860	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482005861	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 1.1e-38
553482005862	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 3.1e-10
553482005863	Predicted helix-turn-helix motif with score 985.000, SD 2.54 at aa 10-31, sequence VALEDLMQLLSSSESTVRRDLD
553482005864	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
553482005865	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005866	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
553482005867	HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 9.1e-55
553482005868	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 5.3e-58
553482005869	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005870	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482005871	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
553482005872	8 transmembrane helices predicted for SEQ1303 by TMHMM2.0 at aa 16-38, 48-70, 109-131, 141-163, 184-206, 216-238, 266-288 and 308-330
553482005873	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
553482005874	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005875	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482005876	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2.5e-13
553482005877	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 2.7e-10
553482005878	1 transmembrane helix predicted for SEQ1304 by TMHMM2.0 at aa 5-24
553482005879	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
553482005880	HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase, score 7.9e-74
553482005881	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
553482005882	RimM N-terminal domain; Region: RimM; pfam01782
553482005883	Photosynthetic reaction center (RC) complex, subunit H;  RC is an integral membrane protein-pigment complex which catalyzes light-induced reduction of ubiquinone to ubiquinol, generating a transmembrane electrochemical gradient of protons used to produce...; Region: PRCH; cl09959
553482005884	HMMPfam hit to PF05239, PRC-barrel domain, score 1.3e-17
553482005885	HMMPfam hit to PF01782, RimM N-terminal domain, score 7.4e-34
553482005886	gene remnant
553482005887	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
553482005888	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cl00098
553482005889	Ribosomal protein S16; Region: Ribosomal_S16; cl00368
553482005890	HMMPfam hit to PF00886, Ribosomal protein S16, score 1.9e-30
553482005891	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
553482005892	5 transmembrane helices predicted for SEQ1309 by TMHMM2.0 at aa 15-34, 54-76, 86-108, 143-162 and 172-194
553482005893	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482005894	FtsX-like permease family; Region: FtsX; cl15850
553482005895	HMMPfam hit to PF02687, Predicted permease, score 4.4e-45
553482005896	4 transmembrane helices predicted for SEQ1310 by TMHMM2.0 at aa 20-42, 284-306, 337-359 and 366-388
553482005897	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482005898	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482005899	Walker A/P-loop; other site
553482005900	ATP binding site [chemical binding]; other site
553482005901	Q-loop/lid; other site
553482005902	ABC transporter signature motif; other site
553482005903	Walker B; other site
553482005904	D-loop; other site
553482005905	H-loop/switch region; other site
553482005906	HMMPfam hit to PF00005, ABC transporter, score 1e-60
553482005907	PS00211 ABC transporters family signature.
553482005908	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005909	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
553482005910	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
553482005911	1 transmembrane helix predicted for SEQ1312 by TMHMM2.0 at aa 16-33
553482005912	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
553482005913	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482005914	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482005915	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
553482005916	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482005917	ATP-grasp domain; Region: ATP-grasp_4; cl03087
553482005918	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
553482005919	IMP binding site; other site
553482005920	dimer interface [polypeptide binding]; other site
553482005921	interdomain contacts; other site
553482005922	partial ornithine binding site; other site
553482005923	HMMPfam hit to PF02142, MGS-like domain, score 7.5e-26
553482005924	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.2e-32
553482005925	HMMPfam hit to PF02655, ATP-grasp domain, score 9.6e-06
553482005926	HMMPfam hit to PF02222, ATP-grasp domain, score 0.00013
553482005927	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.00047
553482005928	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482005929	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482005930	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.9e-27
553482005931	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 1e-60
553482005932	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 7.2e-139
553482005933	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482005934	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482005935	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 6.1e-56
553482005936	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
553482005937	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; cl03056
553482005938	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
553482005939	catalytic site [active]
553482005940	subunit interface [polypeptide binding]; other site
553482005941	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.7e-65
553482005942	PS00442 Glutamine amidotransferases class-I active site.
553482005943	HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small ch, score 1.9e-87
553482005944	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
553482005945	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
553482005946	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482005947	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 3.2e-32
553482005948	Predicted helix-turn-helix motif with score 1181.000, SD 3.21 at aa 236-257, sequence FSKEDYHRQFGLTEERYRRLKD
553482005949	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 1.4e-39
553482005950	PS00097 Aspartate and ornithine carbamoyltransferases signature.
553482005951	uracil transporter; Provisional; Region: PRK10720
553482005952	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
553482005953	11 transmembrane helices predicted for SEQ1316 by TMHMM2.0 at aa 26-48, 55-77, 87-109, 120-142, 152-174, 176-198, 237-259, 310-332, 342-364, 376-394 and 399-416
553482005954	HMMPfam hit to PF00860, Permease family, score 2.9e-105
553482005955	PS01116 Xanthine/uracil permeases family signature.
553482005956	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482005957	active site
553482005958	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.1e-16
553482005959	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
553482005960	5 transmembrane helices predicted for SEQ1318 by TMHMM2.0 at aa 13-32, 52-74, 81-103, 143-165 and 172-194
553482005961	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
553482005962	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482005963	RNA binding surface [nucleotide binding]; other site
553482005964	PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and...; Region: PseudoU_synth_RluCD_like; cd02869
553482005965	active site
553482005966	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 5.9e-71
553482005967	PS01129 Rlu family of pseudouridine synthase signature.
553482005968	HMMPfam hit to PF01479, S4 domain, score 7.4e-09
553482005969	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
553482005970	lipoprotein signal peptidase; Provisional; Region: PRK14787
553482005971	HMMPfam hit to PF01252, Signal peptidase (SPase) II, score 9.1e-44
553482005972	3 transmembrane helices predicted for SEQ1320 by TMHMM2.0 at aa 61-79, 84-103 and 123-145
553482005973	Transcriptional regulator [Transcription]; Region: LysR; COG0583
553482005974	Helix-turn-helix domains; Region: HTH; cl00088
553482005975	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482005976	dimerization interface [polypeptide binding]; other site
553482005977	HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-12
553482005978	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.8e-18
553482005979	PS00044 Bacterial regulatory proteins, lysR family signature.
553482005980	Predicted helix-turn-helix motif with score 1362.000, SD 3.83 at aa 16-37, sequence GTFREAASKLFVSQPSLSVSVK
553482005981	Ribosomal L27 protein; Region: Ribosomal_L27; cl00359
553482005982	HMMPfam hit to PF01016, Ribosomal L27 protein, score 1.2e-47
553482005983	PS00831 Ribosomal protein L27 signature.
553482005984	Protein of unknown function (DUF464); Region: DUF464; cl01080
553482005985	HMMPfam hit to PF04327, Protein of unknown function (DUF464), score 2.5e-29
553482005986	Ribosomal prokaryotic L21 protein; Region: Ribosomal_L21p; cl00382
553482005987	HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein, score 5.1e-56
553482005988	PS01169 Ribosomal protein L21 signature.
553482005989	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
553482005990	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
553482005991	putative active site [active]
553482005992	putative metal binding site [ion binding]; other site
553482005993	1 transmembrane helix predicted for SEQ1325 by TMHMM2.0 at aa 12-34
553482005994	Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978
553482005995	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005996	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482005997	11 transmembrane helices predicted for SEQ1327 by TMHMM2.0 at aa 13-35, 45-64, 76-95, 99-116, 137-159, 169-188, 229-251, 264-286, 306-335, 361-383 and 388-407
553482005998	CDS contains frameshifts after codons 286 and 326. Similar to Lactococcus lactis hypothetical protein UniProt:O87250 (EMBL:AE001272 (614 aa) fasta scores: E()=2e-32, 32.921% id in 647 aa
553482005999	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482006000	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482006001	putative transposase OrfB; Reviewed; Region: PHA02517
553482006002	HTH-like domain; Region: HTH_21; pfam13276
553482006003	Integrase core domain; Region: rve; cl01316
553482006004	Integrase core domain; Region: rve_3; cl15866
553482006005	HMMPfam hit to PF00665, Integrase core domain, score 5.4e-39
553482006006	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006007	Helix-turn-helix domains; Region: HTH; cl00088
553482006008	HMMPfam hit to PF01527, Transposase, score 0.00051
553482006009	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482006010	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482006011	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482006012	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482006013	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
553482006014	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
553482006015	RNA binding site [nucleotide binding]; other site
553482006016	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
553482006017	RNA binding site [nucleotide binding]; other site
553482006018	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482006019	RNA binding site [nucleotide binding]; other site
553482006020	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists of...; Region: S1_RPS1_repeat_hs4; cd05692
553482006021	RNA binding site [nucleotide binding]; other site
553482006022	HMMPfam hit to PF00575, S1 RNA binding domain, score 3e-30
553482006023	HMMPfam hit to PF00575, S1 RNA binding domain, score 2.5e-27
553482006024	HMMPfam hit to PF00575, S1 RNA binding domain, score 3.5e-15
553482006025	HMMPfam hit to PF00575, S1 RNA binding domain, score 0.004
553482006026	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
553482006027	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
553482006028	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
553482006029	homodimer interface [polypeptide binding]; other site
553482006030	substrate-cofactor binding pocket; other site
553482006031	catalytic residue [active]
553482006032	HMMPfam hit to PF01063, Aminotransferase class IV, score 9.8e-115
553482006033	PS00770 Aminotransferases class-IV signature.
553482006034	DNA topoisomerase IV, A subunit, Gram-positive; Region: parC_Gpos; TIGR01061
553482006035	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA...; Region: TOP4c; cd00187
553482006036	CAP-like domain; other site
553482006037	active site
553482006038	primary dimer interface [polypeptide binding]; other site
553482006039	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482006040	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.045
553482006041	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 9.6e-11
553482006042	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.1
553482006043	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 9.2e-05
553482006044	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.062
553482006045	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 7.6e-278
553482006046	DNA topoisomerase IV, B subunit, Gram-positive; Region: parE_Gpos; TIGR01058
553482006047	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482006048	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
553482006049	anchoring element; other site
553482006050	dimer interface [polypeptide binding]; other site
553482006051	ATP binding site [chemical binding]; other site
553482006052	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
553482006053	active site
553482006054	putative metal-binding site [ion binding]; other site
553482006055	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
553482006056	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 4.5e-44
553482006057	HMMPfam hit to PF01751, Toprim domain, score 0.00085
553482006058	PS00177 DNA topoisomerase II signature.
553482006059	HMMPfam hit to PF00204, DNA gyrase B, score 1.6e-86
553482006060	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 1e-29
553482006061	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
553482006062	6 transmembrane helices predicted for SEQ1341 by TMHMM2.0 at aa 5-27, 42-61, 68-90, 105-127, 134-156 and 166-183
553482006063	HMMPfam hit to PF02660, Domain of unknown function DUF, score 3.7e-52
553482006064	dihydroorotase; Validated; Region: pyrC; PRK09357
553482006065	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482006066	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
553482006067	active site
553482006068	HMMPfam hit to PF01979, Amidohydrolase family, score 9.1e-19
553482006069	HMMPfam hit to PF07969, Amidohydrolase family, score 0.00052
553482006070	PS00483 Dihydroorotase signature 2.
553482006071	PS00482 Dihydroorotase signature 1.
553482006072	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
553482006073	ligand binding site [chemical binding]; other site
553482006074	active site
553482006075	UGI interface [polypeptide binding]; other site
553482006076	catalytic site [active]
553482006077	PS00130 Uracil-DNA glycosylase signature.
553482006078	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482006079	Coenzyme A binding pocket [chemical binding]; other site
553482006080	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-16
553482006081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006082	dimer interface [polypeptide binding]; other site
553482006083	conserved gate region; other site
553482006084	putative PBP binding loops; other site
553482006085	ABC-ATPase subunit interface; other site
553482006086	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.5e-29
553482006087	5 transmembrane helices predicted for SEQ1345 by TMHMM2.0 at aa 20-42, 54-76, 80-102, 123-145 and 184-202
553482006088	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006089	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006090	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006091	substrate binding pocket [chemical binding]; other site
553482006092	membrane-bound complex binding site; other site
553482006093	hinge residues; other site
553482006094	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2.6e-69
553482006095	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
553482006096	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006097	amidase; Provisional; Region: PRK06529
553482006098	Amidase; Region: Amidase; cl11426
553482006099	HMMPfam hit to PF01425, Amidase, score 9.9e-74
553482006100	PS00571 Amidases signature.
553482006101	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482006102	Coenzyme A binding pocket [chemical binding]; other site
553482006103	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.8e-12
553482006104	orotate phosphoribosyltransferase; Validated; Region: pyrE; PRK00455
553482006105	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482006106	active site
553482006107	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.8e-28
553482006108	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482006109	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
553482006110	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase contains two...; Region: OMP_decarboxylase_like; cd04725
553482006111	active site
553482006112	dimer interface [polypeptide binding]; other site
553482006113	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 5.5e-76
553482006114	PS00156 Orotidine 5'-phosphate decarboxylase active site.
553482006115	Transcriptional regulator [Transcription]; Region: LysR; COG0583
553482006116	Helix-turn-helix domains; Region: HTH; cl00088
553482006117	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482006118	dimerization interface [polypeptide binding]; other site
553482006119	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 3.7e-19
553482006120	Predicted helix-turn-helix motif with score 1543.000, SD 4.44 at aa 16-37, sequence GSMNEAAKQLFITQPSLSNAVK
553482006121	PS00044 Bacterial regulatory proteins, lysR family signature.
553482006122	CRISPR/Cas system-associated protein Csm6; Region: Csm6_III-A; cl09873
553482006123	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
553482006124	HMMPfam hit to PF00896, Phosphorylase family, score 1.2e-102
553482006125	PS01240 Purine and other phosphorylases family 2 signature.
553482006126	Sulfatase; Region: Sulfatase; cl10460
553482006127	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
553482006128	HMMPfam hit to PF08342, Phosphopentomutase N-terminal, score 9.1e-47
553482006129	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
553482006130	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482006131	active site
553482006132	dimer interface [polypeptide binding]; other site
553482006133	HMMPfam hit to PF06026, Ribose 5-phosphate isomerase A (phosph, score 2.6e-95
553482006134	Domain of unknown function (DUF4176); Region: DUF4176; cl01867
553482006135	4 transmembrane helices predicted for SEQ1358 by TMHMM2.0 at aa 52-74, 89-111, 151-173 and 188-210
553482006136	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006137	4 transmembrane helices predicted for SEQ1359 by TMHMM2.0 at aa 53-75, 90-112, 154-176 and 191-213
553482006138	4 transmembrane helices predicted for SEQ1360 by TMHMM2.0 at aa 53-75, 90-112, 150-172 and 185-207
553482006139	gene remnant. Similar to the C-terminal region of Streptococcus agalactiae serotype Ia uncharacterized protein UniProt:Q3K164 (EMBL:CP000114) (104 aa) fasta scores: E()=4.8e-14, 50.0% id in 74 aa
553482006140	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
553482006141	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
553482006142	trmE is a tRNA modification GTPase; Region: trmE; cd04164
553482006143	G1 box; other site
553482006144	GTP/Mg2+ binding site [chemical binding]; other site
553482006145	Switch I region; other site
553482006146	G2 box; other site
553482006147	Switch II region; other site
553482006148	G3 box; other site
553482006149	G4 box; other site
553482006150	G5 box; other site
553482006151	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
553482006152	HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-45
553482006153	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006154	dipeptidase PepV; Reviewed; Region: PRK07318
553482006155	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
553482006156	active site
553482006157	metal binding site [ion binding]; metal-binding site
553482006158	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 8.9e-32
553482006159	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
553482006160	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
553482006161	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
553482006162	dimer interface [polypeptide binding]; other site
553482006163	FMN binding site [chemical binding]; other site
553482006164	HMMPfam hit to PF00881, Nitroreductase family, score 6.8e-18
553482006165	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
553482006166	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
553482006167	GIY-YIG motif/motif A; other site
553482006168	active site
553482006169	catalytic site [active]
553482006170	putative DNA binding site [nucleotide binding]; other site
553482006171	metal binding site [ion binding]; metal-binding site
553482006172	UvrB/uvrC motif; Region: UVR; pfam02151
553482006173	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
553482006174	HMMPfam hit to PF08459, UvrC Helix-hairpin-helix N-terminal, score 5.7e-88
553482006175	HMMPfam hit to PF02151, UvrB/uvrC motif, score 8.6e-09
553482006176	HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 2.6e-33
553482006177	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482006178	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
553482006179	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.4e-07
553482006180	1 transmembrane helix predicted for SEQ1369 by TMHMM2.0 at aa 7-26
553482006181	Response regulator receiver domain; Region: Response_reg; pfam00072
553482006182	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482006183	active site
553482006184	phosphorylation site [posttranslational modification]
553482006185	intermolecular recognition site; other site
553482006186	dimerization interface [polypeptide binding]; other site
553482006187	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482006188	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
553482006189	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482006190	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6.6e-06
553482006191	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6.7e-10
553482006192	Predicted helix-turn-helix motif with score 1260.000, SD 3.48 at aa 165-186, sequence IMIGQLAHDLGYSESHLYHLAK
553482006193	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-16
553482006194	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482006195	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
553482006196	Histidine kinase; Region: His_kinase; pfam06580
553482006197	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482006198	Mg2+ binding site [ion binding]; other site
553482006199	G-X-G motif; other site
553482006200	HMMPfam hit to PF06580, Histidine kinase, score 4.7e-30
553482006201	2 transmembrane helices predicted for SEQ1371 by TMHMM2.0 at aa 21-43 and 254-276
553482006202	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
553482006203	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 1.9e-134
553482006204	5 transmembrane helices predicted for SEQ1372 by TMHMM2.0 at aa 35-52, 126-148, 155-174, 232-249 and 256-274
553482006205	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
553482006206	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 8.7e-38
553482006207	7 transmembrane helices predicted for SEQ1373 by TMHMM2.0 at aa 4-23, 30-52, 62-84, 96-118, 143-165, 178-200 and 210-232
553482006208	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
553482006209	active site
553482006210	phosphorylation site [posttranslational modification]
553482006211	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 6.8e-71
553482006212	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
553482006213	active pocket/dimerization site; other site
553482006214	active site
553482006215	phosphorylation site [posttranslational modification]
553482006216	HMMPfam hit to PF03610, PTS system fructose IIA component, score 0.00028
553482006217	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
553482006218	8 transmembrane helices predicted for SEQ1376 by TMHMM2.0 at aa 22-44, 57-79, 84-106, 118-140, 150-172, 257-279, 289-308 and 315-337
553482006219	HMMPfam hit to PF03601, Conserved hypothetical protein, score 1.4e-129
553482006220	methionine sulfoxide reductase B; Provisional; Region: PRK00222; cl15841
553482006221	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
553482006222	HMMPfam hit to PF01641, SelR domain, score 3.1e-79
553482006223	GTP-binding protein LepA; Provisional; Region: PRK05433
553482006224	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
553482006225	G1 box; other site
553482006226	putative GEF interaction site [polypeptide binding]; other site
553482006227	GTP/Mg2+ binding site [chemical binding]; other site
553482006228	Switch I region; other site
553482006229	G2 box; other site
553482006230	G3 box; other site
553482006231	Switch II region; other site
553482006232	G4 box; other site
553482006233	G5 box; other site
553482006234	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
553482006235	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
553482006236	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
553482006237	HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 2.5e-82
553482006238	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 3.6e-41
553482006239	HMMPfam hit to PF03144, Elongation factor Tu domain, score 9.4e-06
553482006240	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.1e-71
553482006241	PS00301 GTP-binding elongation factors signature.
553482006242	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006243	gene remnant. Similar to the C-terminal region of Streptococcus agalactiae hypothetical protein UniProt:Q3D902 (EMBL:AAJR01000020 (133 aa) fasta scores: E()=2.4e-14, 56.522% id in 92 aa
553482006244	2 transmembrane helices predicted for SEQ1380 by TMHMM2.0 at aa 27-46 and 59-81
553482006245	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482006246	Class II bacteriocin; Region: Bacteriocin_II; pfam01721
553482006247	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M3 bacteriocin processing peptidase/bacteriocin export ABC transporter UniProt:Q1J803 (EMBL:CP000262 (717 aa) fasta scores: E()=3e-32, 81.935% id in 155 aa
553482006248	HMMPfam hit to PF00005, ABC transporter, score 7.3e-19
553482006249	PS00211 ABC transporters family signature.
553482006250	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482006251	CDS contains nonsense mutations (ochre and amber) after codons 204 and 284. Similar to Streptococcus pneumoniae transport protein ComB UniProt:P36498 (EMBL:AE005672 (449 aa) fasta scores: E()=3.8e-43, 34.824% id in 425 aa
553482006252	COMC family; Region: ComC; pfam03047
553482006253	HMMPfam hit to PF08128, Double glycine cleavage site bacterio, score 2.6e-11
553482006255	HMMPfam hit to PF01797, Transposase IS200 like, score 4.8e-23
553482006256	Transposase IS200 like; Region: Y1_Tnp; cl00848
553482006257	HMMPfam hit to PF01797, Transposase IS200 like, score 9.7e-54
553482006258	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
553482006259	core dimer interface [polypeptide binding]; other site
553482006260	L10 interface [polypeptide binding]; other site
553482006261	L11 interface [polypeptide binding]; other site
553482006262	putative EF-Tu interaction site [polypeptide binding]; other site
553482006263	putative EF-G interaction site [polypeptide binding]; other site
553482006264	HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal dom, score 4.3e-37
553482006265	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
553482006266	23S rRNA interface [nucleotide binding]; other site
553482006267	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
553482006268	HMMPfam hit to PF00466, Ribosomal protein L10, score 2.2e-28
553482006269	Protein of unknown function (DUF1461); Region: DUF1461; cl01862
553482006270	4 transmembrane helices predicted for SEQ1392 by TMHMM2.0 at aa 7-29, 91-113, 120-142 and 178-200
553482006271	HMMPfam hit to PF07314, Protein of unknown function (DUF1461), score 1.2e-81
553482006272	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482006273	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006274	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
553482006275	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006276	active site
553482006277	motif I; other site
553482006278	motif II; other site
553482006279	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006280	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.8e-22
553482006281	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
553482006282	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
553482006283	active site
553482006284	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
553482006285	active site 2 [active]
553482006286	active site 1 [active]
553482006287	HMMPfam hit to PF01643, Acyl-ACP thioesterase, score 4.1e-95
553482006288	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
553482006289	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482006290	FeS/SAM binding site; other site
553482006291	HemN C-terminal domain; Region: HemN_C; pfam06969
553482006292	HMMPfam hit to PF06969, HemN C-terminal region, score 4.7e-45
553482006293	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
553482006294	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
553482006295	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
553482006296	active site
553482006297	substrate binding site [chemical binding]; other site
553482006298	metal binding site [ion binding]; metal-binding site
553482006299	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 4e-06
553482006300	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 4.8e-24
553482006301	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 2.5e-20
553482006302	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 2.5e-58
553482006303	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482006304	YbbR-like protein; Region: YbbR; pfam07949
553482006305	YbbR-like protein; Region: YbbR; pfam07949
553482006306	HMMPfam hit to PF07949, YbbR-like protein, score 0.00012
553482006307	HMMPfam hit to PF07949, YbbR-like protein, score 9.8e-13
553482006308	HMMPfam hit to PF07949, YbbR-like protein, score 1.9e-13
553482006309	1 transmembrane helix predicted for SEQ1398 by TMHMM2.0 at aa 7-29
553482006310	Uncharacterized conserved protein [Function unknown]; Region: COG1624
553482006311	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
553482006312	HMMPfam hit to PF02457, Domain of unknown function DUF147, score 8.4e-59
553482006313	3 transmembrane helices predicted for SEQ1399 by TMHMM2.0 at aa 15-37, 49-71 and 81-100
553482006314	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
553482006315	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482006316	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
553482006317	HMMPfam hit to PF08245, Mur ligase middle domain, score 1.1e-06
553482006318	HMMPfam hit to PF08353, Domain of unknown function (DUF1727), score 7e-55
553482006319	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
553482006320	catalytic triad [active]
553482006321	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 4.3e-49
553482006322	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
553482006323	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
553482006324	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
553482006325	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 1.7e-22
553482006326	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
553482006327	E3 interaction surface; other site
553482006328	lipoyl attachment site [posttranslational modification]; other site
553482006329	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
553482006330	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482006331	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482006332	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1e-52
553482006333	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 1.2e-05
553482006334	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 1.4e-60
553482006335	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.2e-27
553482006336	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482006337	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.5e-22
553482006338	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
553482006339	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
553482006340	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
553482006341	E3 interaction surface; other site
553482006342	lipoyl attachment site [posttranslational modification]; other site
553482006343	e3 binding domain; Region: E3_binding; pfam02817
553482006344	e3 binding domain; Region: E3_binding; pfam02817
553482006345	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; cl02008
553482006346	HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 8.6e-116
553482006347	HMMPfam hit to PF02817, e3 binding domain, score 3.4e-15
553482006348	HMMPfam hit to PF02817, e3 binding domain, score 1.2e-16
553482006349	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 3e-22
553482006350	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
553482006351	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
553482006352	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
553482006353	alpha subunit interface [polypeptide binding]; other site
553482006354	TPP binding site [chemical binding]; other site
553482006355	heterodimer interface [polypeptide binding]; other site
553482006356	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482006357	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 5.9e-55
553482006358	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.1e-64
553482006359	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
553482006360	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
553482006361	tetramer interface [polypeptide binding]; other site
553482006362	TPP-binding site [chemical binding]; other site
553482006363	heterodimer interface [polypeptide binding]; other site
553482006364	phosphorylation loop region [posttranslational modification]
553482006365	HMMPfam hit to PF00676, Dehydrogenase E1 component, score 6.6e-106
553482006366	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
553482006367	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482006368	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482006369	ABC transporter; Region: ABC_tran_2; pfam12848
553482006370	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482006371	HMMPfam hit to PF00005, ABC transporter, score 2.5e-32
553482006372	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006373	HMMPfam hit to PF00005, ABC transporter, score 5.2e-46
553482006374	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006375	Predicted esterase [General function prediction only]; Region: COG0627
553482006376	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482006377	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482006378	HMMPfam hit to PF02230, Phospholipase/Carboxylesterase, score 0.0017
553482006379	HMMPfam hit to PF00756, esterase, score 1.3e-05
553482006380	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
553482006381	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482006382	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
553482006383	HMMPfam hit to PF07521, RNA-metabolising metallo-beta-lactamase, score 3e-11
553482006384	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
553482006385	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482006386	Walker A/P-loop; other site
553482006387	ATP binding site [chemical binding]; other site
553482006388	Q-loop/lid; other site
553482006389	ABC transporter signature motif; other site
553482006390	Walker B; other site
553482006391	D-loop; other site
553482006392	H-loop/switch region; other site
553482006393	HMMPfam hit to PF00005, ABC transporter, score 2e-43
553482006394	PS00211 ABC transporters family signature.
553482006395	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006396	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
553482006397	TM-ABC transporter signature motif; other site
553482006398	8 transmembrane helices predicted for SEQ1411 by TMHMM2.0 at aa 9-28, 54-76, 83-105, 125-147, 176-195, 205-227, 234-256 and 260-282
553482006399	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 8.2e-23
553482006400	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006401	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482006402	zinc binding site [ion binding]; other site
553482006403	putative ligand binding site [chemical binding]; other site
553482006404	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 5e-129
553482006405	1 transmembrane helix predicted for SEQ1412 by TMHMM2.0 at aa 5-23
553482006406	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
553482006407	Domain of unknown function (DUF814); Region: DUF814; pfam05670
553482006408	HMMPfam hit to PF05833, Fibronectin-binding protein A N-terminus (Fb, score 3.2e-228
553482006409	HMMPfam hit to PF05670, Domain of unknown function (DUF814), score 8.7e-39
553482006410	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
553482006411	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
553482006412	binding surface
553482006413	TPR motif; other site
553482006414	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
553482006415	binding surface
553482006416	TPR motif; other site
553482006417	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2e-05
553482006418	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
553482006419	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; cl00465
553482006420	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 3.9e-71
553482006421	7 transmembrane helices predicted for SEQ1415 by TMHMM2.0 at aa 18-40, 49-71, 86-108, 178-200, 240-262, 269-291 and 332-354
553482006422	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
553482006423	putative active site [active]
553482006424	nucleotide binding site [chemical binding]; other site
553482006425	nudix motif; other site
553482006426	putative metal binding site [ion binding]; other site
553482006427	HMMPfam hit to PF00293, NUDIX domain, score 4.3e-26
553482006428	PS00893 mutT domain signature.
553482006429	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
553482006430	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
553482006431	NAD binding site [chemical binding]; other site
553482006432	substrate binding site [chemical binding]; other site
553482006433	homodimer interface [polypeptide binding]; other site
553482006434	active site
553482006435	HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00023
553482006436	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.1e-05
553482006437	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 8.6e-79
553482006438	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0042
553482006439	HMMPfam hit to PF07993, Male sterility protein, score 4.8e-08
553482006440	Cupin domain; Region: Cupin_2; cl09118
553482006441	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 2.1e-14
553482006442	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
553482006443	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
553482006444	substrate binding site; other site
553482006445	tetramer interface; other site
553482006446	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5e-119
553482006447	FAD dependent oxidoreductase; Region: DAO; pfam01266
553482006448	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.8e-64
553482006449	Uncharacterized conserved protein [Function unknown]; Region: COG0327
553482006450	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
553482006451	HMMPfam hit to PF01784, NIF3 (NGG1p interacting factor 3), score 7.3e-95
553482006452	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482006453	HMMPfam hit to PF04816, Family of unknown function (DUF633), score 8e-108
553482006454	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
553482006455	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
553482006456	minor groove reading motif; other site
553482006457	helix-hairpin-helix signature motif; other site
553482006458	substrate binding pocket [chemical binding]; other site
553482006459	active site
553482006460	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
553482006461	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482006462	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 5.8e-08
553482006463	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
553482006464	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
553482006465	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482006466	active site
553482006467	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.2e-46
553482006468	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482006469	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; cl12126
553482006470	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
553482006471	DHH family; Region: DHH; pfam01368
553482006472	DHHA1 domain; Region: DHHA1; pfam02272
553482006473	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
553482006474	HMMPfam hit to PF02272, DHHA1 domain, score 3e-12
553482006475	HMMPfam hit to PF01368, DHH family, score 1.2e-50
553482006476	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
553482006477	classical (c) SDRs; Region: SDR_c; cd05233
553482006478	NAD(P) binding site [chemical binding]; other site
553482006479	active site
553482006480	HMMPfam hit to PF00106, short chain dehydrogenase, score 7e-23
553482006481	PS00061 Short-chain dehydrogenases/reductases family signature.
553482006482	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482006483	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
553482006484	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
553482006485	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
553482006486	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
553482006487	HflX GTPase family; Region: HflX; cd01878
553482006488	G1 box; other site
553482006489	GTP/Mg2+ binding site [chemical binding]; other site
553482006490	Switch I region; other site
553482006491	G2 box; other site
553482006492	G3 box; other site
553482006493	Switch II region; other site
553482006494	G4 box; other site
553482006495	G5 box; other site
553482006496	HMMPfam hit to PF01926, GTPase of unknown function, score 1.2e-36
553482006497	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006498	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482006499	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
553482006500	HMMPfam hit to PF01715, IPP transferase, score 8.1e-66
553482006501	1 transmembrane helix predicted for SEQ1432 by TMHMM2.0 at aa 7-29
553482006502	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006503	1 transmembrane helix predicted for SEQ1433 by TMHMM2.0 at aa 7-29
553482006504	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482006505	active site
553482006506	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 5.4e-05
553482006507	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006508	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
553482006509	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
553482006510	HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 4.3e-183
553482006511	PS00102 Phosphorylase pyridoxal-phosphate attachment site.
553482006512	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
553482006513	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
553482006514	HMMPfam hit to PF02446, 4-alpha-glucanotransferase, score 2.2e-191
553482006515	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482006516	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482006517	DNA binding site [nucleotide binding]
553482006518	domain linker motif; other site
553482006519	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
553482006520	putative dimerization interface [polypeptide binding]; other site
553482006521	putative ligand binding site [chemical binding]; other site
553482006522	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.9e-08
553482006523	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.4e-08
553482006524	Predicted helix-turn-helix motif with score 2360.000, SD 7.22 at aa 2-23, sequence VTIKDVALKAGVNPSTVSRVLK
553482006525	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
553482006526	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482006527	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.8e-26
553482006528	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006529	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006530	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006531	dimer interface [polypeptide binding]; other site
553482006532	conserved gate region; other site
553482006533	ABC-ATPase subunit interface; other site
553482006534	8 transmembrane helices predicted for SEQ1439 by TMHMM2.0 at aa 47-69, 98-120, 162-184, 222-244, 257-279, 309-331, 352-374 and 419-441
553482006535	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-12
553482006536	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006537	ABC-type maltose transport systems, permease component [Carbohydrate transport and metabolism]; Region: MalG; COG3833
553482006538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006539	dimer interface [polypeptide binding]; other site
553482006540	conserved gate region; other site
553482006541	putative PBP binding loops; other site
553482006542	ABC-ATPase subunit interface; other site
553482006543	6 transmembrane helices predicted for SEQ1440 by TMHMM2.0 at aa 9-31, 75-97, 110-129, 139-161, 182-204 and 242-264
553482006544	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-17
553482006545	PS00041 Bacterial regulatory proteins, araC family signature.
553482006546	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006547	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006548	Helix-turn-helix domains; Region: HTH; cl00088
553482006549	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482006550	HMMPfam hit to PF01527, Transposase, score 0.00062
553482006551	HMMPfam hit to PF02178, no description, score 0.21
553482006552	putative transposase OrfB; Reviewed; Region: PHA02517
553482006553	HTH-like domain; Region: HTH_21; pfam13276
553482006554	Integrase core domain; Region: rve; cl01316
553482006555	Integrase core domain; Region: rve_3; cl15866
553482006556	HMMPfam hit to PF00665, Integrase core domain, score 9.5e-38
553482006557	Predicted integral membrane protein [Function unknown]; Region: COG5521
553482006558	4 transmembrane helices predicted for SEQ1443 by TMHMM2.0 at aa 27-49, 176-198, 219-241 and 245-264
553482006559	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006560	dimer interface [polypeptide binding]; other site
553482006561	conserved gate region; other site
553482006562	putative PBP binding loops; other site
553482006563	ABC-ATPase subunit interface; other site
553482006564	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.8e-24
553482006565	5 transmembrane helices predicted for SEQ1444 by TMHMM2.0 at aa 21-43, 81-103, 115-137, 142-164 and 250-272
553482006566	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006567	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006568	dimer interface [polypeptide binding]; other site
553482006569	conserved gate region; other site
553482006570	putative PBP binding loops; other site
553482006571	ABC-ATPase subunit interface; other site
553482006572	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.5e-20
553482006573	8 transmembrane helices predicted for SEQ1445 by TMHMM2.0 at aa 34-56, 71-93, 127-149, 196-218, 230-252, 291-313, 338-357 and 401-423
553482006574	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006575	Alpha amylase catalytic domain found in maltogenic amylases, cyclodextrin glycosyltransferase, and related proteins; Region: AmyAc_AmyMalt_CGTase_like; cd11320
553482006576	Ca binding site [ion binding]; other site
553482006577	active site
553482006578	catalytic site [active]
553482006579	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
553482006580	IPT domain (domain D) of cyclodextrin glycosyltransferase (CGTase) and similar enzymes. These enzymes are involved in the enzymatic hydrolysis of alpha-1,4 linkages of starch polymers and belong to the glycosyl hydrolase family 13. Most consist of three...; Region: IPT_CGTD; cd00604
553482006581	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cl15347
553482006582	starch-binding site 2 [chemical binding]; other site
553482006583	starch-binding site 1 [chemical binding]; other site
553482006584	HMMPfam hit to PF00686, Starch binding domain, score 1.1e-15
553482006585	HMMPfam hit to PF01833, IPT/TIG domain, score 1.4e-10
553482006586	HMMPfam hit to PF02806, Alpha amylase, C-terminal all-beta do, score 1.1e-25
553482006587	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 7.9e-110
553482006588	PS00962 Ribosomal protein S2 signature 1.
553482006589	maltodextrin glucosidase; Provisional; Region: PRK10785
553482006590	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
553482006591	homodimer interface [polypeptide binding]; other site
553482006592	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
553482006593	active site
553482006594	homodimer interface [polypeptide binding]; other site
553482006595	catalytic site [active]
553482006596	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.6e-91
553482006597	HMMPfam hit to PF02903, Alpha amylase, N-terminal ig-like dom, score 3.7e-10
553482006598	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
553482006599	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482006600	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.8e-39
553482006601	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006602	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482006603	HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 4e-18
553482006604	1 transmembrane helix predicted for SEQ1449 by TMHMM2.0 at aa 5-22
553482006605	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
553482006606	DltD N-terminal region; Region: DltD_N; pfam04915
553482006607	DltD central region; Region: DltD_M; pfam04918
553482006608	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
553482006609	HMMPfam hit to PF04914, DltD C-terminal region, score 1.8e-79
553482006610	HMMPfam hit to PF04918, DltD central region, score 3e-70
553482006611	HMMPfam hit to PF04915, DltD N-terminal region, score 3.3e-38
553482006612	1 transmembrane helix predicted for SEQ1450 by TMHMM2.0 at aa 5-27
553482006613	Phosphopantetheine attachment site; Region: PP-binding; cl09936
553482006614	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
553482006615	9 transmembrane helices predicted for SEQ1452 by TMHMM2.0 at aa 13-35, 40-57, 64-81, 91-113, 118-136, 193-215, 236-258, 336-358 and 379-401
553482006616	HMMPfam hit to PF03062, MBOAT family, score 2.6e-96
553482006617	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
553482006618	AMP-binding enzyme; Region: AMP-binding; cl15778
553482006619	PS00455 AMP-binding domain signature.
553482006620	excinuclease ABC subunit B; Provisional; Region: PRK05298
553482006621	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482006622	ATP binding site [chemical binding]; other site
553482006623	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482006624	nucleotide binding region [chemical binding]; other site
553482006625	ATP-binding site [chemical binding]; other site
553482006626	Ultra-violet resistance protein B; Region: UvrB; pfam12344
553482006627	HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.6e-08
553482006628	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 7.7e-20
553482006629	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 8.7e-06
553482006630	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006631	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006632	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006633	substrate binding pocket [chemical binding]; other site
553482006634	membrane-bound complex binding site; other site
553482006635	hinge residues; other site
553482006636	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006637	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006638	substrate binding pocket [chemical binding]; other site
553482006639	membrane-bound complex binding site; other site
553482006640	hinge residues; other site
553482006641	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006642	dimer interface [polypeptide binding]; other site
553482006643	conserved gate region; other site
553482006644	putative PBP binding loops; other site
553482006645	ABC-ATPase subunit interface; other site
553482006646	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 2.2e-75
553482006647	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 4.8e-74
553482006648	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.3e-28
553482006649	4 transmembrane helices predicted for SEQ1455 by TMHMM2.0 at aa 518-540, 553-575, 595-617 and 691-713
553482006650	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006651	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482006652	HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, repectively.  Histidine permease is a multisubunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP.  HisP...; Region: ABC_HisP_GlnQ_permeases; cd03262
553482006653	Walker A/P-loop; other site
553482006654	ATP binding site [chemical binding]; other site
553482006655	Q-loop/lid; other site
553482006656	ABC transporter signature motif; other site
553482006657	Walker B; other site
553482006658	D-loop; other site
553482006659	H-loop/switch region; other site
553482006660	HMMPfam hit to PF00005, ABC transporter, score 7.4e-66
553482006661	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006662	PS00211 ABC transporters family signature.
553482006663	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482006664	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482006665	11 transmembrane helices predicted for SEQ1457 by TMHMM2.0 at aa 21-43, 74-96, 103-125, 167-189, 209-231, 251-273, 280-299, 319-341, 371-393, 398-420 and 425-447
553482006666	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.5e-62
553482006667	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
553482006668	hydrophobic ligand binding site; other site
553482006669	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482006670	active site
553482006671	methionine cluster; other site
553482006672	phosphorylation site [posttranslational modification]
553482006673	metal binding site [ion binding]; metal-binding site
553482006674	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 6.4e-38
553482006675	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482006676	active site
553482006677	P-loop; other site
553482006678	phosphorylation site [posttranslational modification]
553482006679	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 2.3e-41
553482006680	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482006681	Helix-turn-helix domains; Region: HTH; cl00088
553482006682	Helix-turn-helix domains; Region: HTH; cl00088
553482006683	PRD domain; Region: PRD; cl15445
553482006684	PRD domain; Region: PRD; cl15445
553482006685	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482006686	P-loop; other site
553482006687	active site
553482006688	phosphorylation site [posttranslational modification]
553482006689	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
553482006690	active site
553482006691	phosphorylation site [posttranslational modification]
553482006692	HMMPfam hit to PF00874, PRD domain, score 5.2e-16
553482006693	HMMPfam hit to PF00874, PRD domain, score 2.9e-16
553482006694	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 1.1e-21
553482006695	Predicted helix-turn-helix motif with score 1309.000, SD 3.65 at aa 114-135, sequence WDFEELCQELYISRTTLNHVLA
553482006696	HMMPfam hit to PF08279, HTH domain, score 6.1e-16
553482006697	Predicted helix-turn-helix motif with score 1653.000, SD 4.82 at aa 21-42, sequence VSSATLAKAIGMSDRTVRKYLK
553482006698	Bacterial protein of unknown function (DUF871); Region: DUF871; cl15404
553482006699	HMMPfam hit to PF05913, Bacterial protein of unknown function (DUF87, score 2e-186
553482006700	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
553482006701	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.2e-112
553482006702	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
553482006703	HMMPfam hit to PF04973, Nicotinamide mononucleotide transport, score 5.4e-43
553482006704	8 transmembrane helices predicted for SEQ1464 by TMHMM2.0 at aa 12-29, 33-51, 56-78, 82-101, 122-139, 144-163, 170-192 and 197-219
553482006705	GTPase CgtA; Reviewed; Region: obgE; PRK12297
553482006706	GTP1/OBG; Region: GTP1_OBG; pfam01018
553482006707	Obg GTPase; Region: Obg; cd01898
553482006708	G1 box; other site
553482006709	GTP/Mg2+ binding site [chemical binding]; other site
553482006710	Switch I region; other site
553482006711	G2 box; other site
553482006712	G3 box; other site
553482006713	Switch II region; other site
553482006714	G4 box; other site
553482006715	G5 box; other site
553482006716	Domain of unknown function (DUF1967); Region: DUF1967; cl07779
553482006717	HMMPfam hit to PF01926, GTPase of unknown function, score 3.6e-40
553482006718	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006719	HMMPfam hit to PF01018, GTP1/OBG, score 9e-83
553482006720	CDS contains a 408 bp internal deletion. Similar to Streptococcus thermophilus aminopeptidase PepS UniProt:Q9X4A7 (EMBL:AF102860 (413 aa) fasta scores: E()=4.9e-47, 54.237% id in 236 aa
553482006721	HMMPfam hit to PF02073, Thermophilic metalloprotease (M29), score 2.3e-28
553482006722	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482006723	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482006724	RNA binding surface [nucleotide binding]; other site
553482006725	PseudoU_synth_RsuA: Pseudouridine synthase, Escherichia coli RsuA like. This group is comprised of eukaryotic and bacterial proteins similar to Escherichia coli RsuA. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA...; Region: PseudoU_synth_RsuA; cd02553
553482006726	active site
553482006727	uracil binding [chemical binding]; other site
553482006728	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 3.4e-19
553482006729	PS01149 Rsu family of pseudouridine synthase signature.
553482006730	HMMPfam hit to PF01479, S4 domain, score 1.4e-11
553482006731	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
553482006732	benzoate transport; Region: 2A0115; TIGR00895
553482006733	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482006734	putative substrate translocation pore; other site
553482006735	HMMPfam hit to PF00083, Sugar (and other) transporter, score 7.8e-06
553482006736	12 transmembrane helices predicted for SEQ1470 by TMHMM2.0 at aa 13-35, 50-69, 82-104, 108-130, 137-159, 163-185, 223-245, 260-279, 286-305, 311-333, 346-368 and 372-394
553482006737	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
553482006738	hypothetical protein; Provisional; Region: PRK13663
553482006739	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006740	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
553482006741	CoenzymeA binding site [chemical binding]; other site
553482006742	subunit interaction site [polypeptide binding]; other site
553482006743	PHB binding site; other site
553482006744	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482006745	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482006746	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00091
553482006747	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482006748	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
553482006749	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 6.9e-26
553482006750	2 transmembrane helices predicted for SEQ1476 by TMHMM2.0 at aa 72-89 and 94-113
553482006751	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006752	Helix-turn-helix domains; Region: HTH; cl00088
553482006753	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482006754	HMMPfam hit to PF01527, Transposase, score 0.00062
553482006755	HMMPfam hit to PF02178, no description, score 0.21
553482006756	putative transposase OrfB; Reviewed; Region: PHA02517
553482006757	HTH-like domain; Region: HTH_21; pfam13276
553482006758	Integrase core domain; Region: rve; cl01316
553482006759	Integrase core domain; Region: rve_3; cl15866
553482006760	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482006761	CDS contains a frameshift around codon 199. Similar to Streptococcus agalactiae serotype V hyaluronidase UniProt:Q8DZB2 (EMBL:AE014246 (1072 aa) fasta scores: E()=6e-166, 45.253% id in 1085 aa, and to Streptococcus agalactiae serotype III hyaluronidase HylB UniProt:Q53591 (EMBL:AL766849 (984 aa) fasta scores: E()=8.3e-163, 47.197% id in 981 aa
553482006762	HMMPfam hit to PF02884, Polysaccharide lyase family 8, C-terminal b, score 0.00027
553482006763	HMMPfam hit to PF02278, Polysaccharide lyase family 8, super-sandwi, score 2.3e-120
553482006764	HMMPfam hit to PF08124, Polysaccharide lyase family 8, N terminal a, score 1.3e-155
553482006765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006766	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
553482006767	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
553482006768	active site
553482006769	intersubunit interface [polypeptide binding]; other site
553482006770	catalytic residue [active]
553482006771	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.1e-28
553482006772	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
553482006773	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
553482006774	substrate binding site [chemical binding]; other site
553482006775	ATP binding site [chemical binding]; other site
553482006776	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.2e-10
553482006777	hypothetical protein; Provisional; Region: PRK09273
553482006778	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
553482006779	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
553482006780	HMMPfam hit to PF06562, ribose 5-phosphate isomerase (DUF11, score 1.1e-152
553482006781	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
553482006782	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
553482006783	NADP binding site [chemical binding]; other site
553482006784	homodimer interface [polypeptide binding]; other site
553482006785	active site
553482006786	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.4e-26
553482006787	PS00061 Short-chain dehydrogenases/reductases family signature.
553482006788	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482006789	active pocket/dimerization site; other site
553482006790	active site
553482006791	phosphorylation site [posttranslational modification]
553482006792	HMMPfam hit to PF03610, PTS system fructose IIA component, score 1.5e-34
553482006793	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
553482006794	HMMPfam hit to PF07470, Glycosyl Hydrolase Family, score 2e-120
553482006795	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482006796	active site
553482006797	phosphorylation site [posttranslational modification]
553482006798	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 1.8e-74
553482006799	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
553482006800	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1.1e-97
553482006801	6 transmembrane helices predicted for SEQ1488 by TMHMM2.0 at aa 5-27, 32-54, 97-119, 140-162, 177-199 and 211-233
553482006802	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
553482006803	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 2.1e-128
553482006804	5 transmembrane helices predicted for SEQ1489 by TMHMM2.0 at aa 100-122, 137-159, 180-202, 228-245 and 250-272
553482006805	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482006806	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482006807	DNA binding site [nucleotide binding]
553482006808	domain linker motif; other site
553482006809	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
553482006810	putative dimerization interface [polypeptide binding]; other site
553482006811	putative ligand binding site [chemical binding]; other site
553482006812	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.9e-05
553482006813	Predicted helix-turn-helix motif with score 1618.000, SD 4.70 at aa 5-26, sequence VTINDIADLAKTSKTTVSFYLN
553482006814	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 7.1e-06
553482006815	CDS contains a nonsense mutation (ochre) in comparison to SZO06550
553482006816	CDS contains a nonsense mutation (opal) in comparison to SZO06550
553482006817	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
553482006818	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; cl02930
553482006819	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
553482006820	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
553482006821	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482006822	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
553482006823	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 3.4e-19
553482006824	8 transmembrane helices predicted for SEQ1497 by TMHMM2.0 at aa 65-82, 86-105, 253-275, 285-307, 682-704, 756-778, 827-849 and 859-881
553482006825	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.7e-19
553482006826	PS00154 E1-E2 ATPases phosphorylation site.
553482006827	HMMPfam hit to PF00122, E1-E2 ATPase, score 1e-100
553482006828	HMMPfam hit to PF00690, Cation transporter/ATPase, N-terminus, score 2.4e-27
553482006829	Domain of unknown function (DUF1934); Region: DUF1934; cl01870
553482006830	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
553482006831	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482006832	Zn2+ binding site [ion binding]; other site
553482006833	Mg2+ binding site [ion binding]; other site
553482006834	HMMPfam hit to PF01966, HD domain, score 9.4e-09
553482006835	sugar phosphate phosphatase; Provisional; Region: PRK10513
553482006836	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006837	active site
553482006838	motif I; other site
553482006839	motif II; other site
553482006840	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482006841	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 7.9e-06
553482006842	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0018
553482006843	PS01228 Hypothetical cof family signature 1.
553482006844	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 2.4e-94
553482006845	PS01229 Hypothetical cof family signature 2.
553482006846	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482006847	HMMPfam hit to PF02388, FemAB family, score 7.5e-12
553482006848	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482006849	HMMPfam hit to PF02388, FemAB family, score 2.7e-120
553482006850	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
553482006851	substrate binding site [chemical binding]; other site
553482006852	dimer interface [polypeptide binding]; other site
553482006853	catalytic triad [active]
553482006854	HMMPfam hit to PF00121, Triosephosphate isomerase, score 2.7e-138
553482006855	PS00171 Triosephosphate isomerase active site.
553482006856	elongation factor Tu; Reviewed; Region: PRK00049
553482006857	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
553482006858	G1 box; other site
553482006859	GEF interaction site [polypeptide binding]; other site
553482006860	GTP/Mg2+ binding site [chemical binding]; other site
553482006861	Switch I region; other site
553482006862	G2 box; other site
553482006863	G3 box; other site
553482006864	Switch II region; other site
553482006865	G4 box; other site
553482006866	G5 box; other site
553482006867	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
553482006868	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
553482006869	Antibiotic Binding Site [chemical binding]; other site
553482006870	HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 3.6e-59
553482006871	HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.1e-23
553482006872	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 5.6e-101
553482006873	PS00301 GTP-binding elongation factors signature.
553482006874	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006875	Viral enhancin protein; Region: Enhancin; pfam03272
553482006876	Viral enhancin protein; Region: Enhancin; pfam03272
553482006877	Viral enhancin protein; Region: Enhancin; pfam03272
553482006878	CDS contains a frameshift around codon 108. Similar to Streptococcus agalactiae hypothetical protein UniProt:Q3D6L8 (EMBL:AAJR01000060 (315 aa) fasta scores: E()=4.9e-23, 32.320% id in 362 aa
553482006879	1 transmembrane helix predicted for SEQ1508 by TMHMM2.0 at aa 20-42
553482006880	RNA polymerase sigma factor, SigM family; Region: SigM_subfam; TIGR02950
553482006881	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482006882	DNA binding residues [nucleotide binding]
553482006883	HMMPfam hit to PF04545, Sigma-70, region, score 6.4e-08
553482006884	HMMPfam hit to PF08281, Sigma-70, region, score 3.8e-16
553482006885	Protein of unknown function (DUF4237); Region: DUF4237; pfam14021
553482006886	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
553482006887	gene remnant. C-terminus is similar to the C-terminal region of Listeria monocytogenes serotype 4b hypothetical protein UniProt:Q724Y9 (EMBL:AE017262 (236 aa) fasta scores: E()=9.8e-26, 45.745% id in 188 aa
553482006888	putative transposase OrfB; Reviewed; Region: PHA02517
553482006889	HTH-like domain; Region: HTH_21; pfam13276
553482006890	Integrase core domain; Region: rve; cl01316
553482006891	Integrase core domain; Region: rve_3; cl15866
553482006892	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482006893	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006894	Helix-turn-helix domains; Region: HTH; cl00088
553482006895	Helix-turn-helix domains; Region: HTH; cl00088
553482006896	HMMPfam hit to PF02178, no description, score 0.21
553482006897	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482006898	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
553482006899	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006900	motif II; other site
553482006901	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.9e-23
553482006902	CDS contains a frameshift after codon 106. Frameshift occurs at a poly T hexamer. Similar to Streptococcus agalactiae serotype Ia drug:H+ antiporter-2 (Dha2) family protein UniProt:Q3JZI6 (EMBL:CP000114 (499 aa) fasta scores: E()=8.1e-121, 68.852% id in 488 aa
553482006903	11 transmembrane helices predicted for SEQ1523 by TMHMM2.0 at aa 10-32, 39-61, 71-91, 112-134, 138-155, 175-197, 212-234, 241-260, 270-292, 313-330 and 358-380
553482006904	3 transmembrane helices predicted for SEQ1524 by TMHMM2.0 at aa 17-39, 54-73 and 85-107
553482006905	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
553482006906	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
553482006907	dimer interface [polypeptide binding]; other site
553482006908	putative anticodon binding site; other site
553482006909	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
553482006910	motif 1; other site
553482006911	active site
553482006912	motif 2; other site
553482006913	motif 3; other site
553482006914	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.1e-17
553482006915	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 6.9e-119
553482006916	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482006917	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482006918	1 transmembrane helix predicted for SEQ1527 by TMHMM2.0 at aa 13-35
553482006919	gene remnant. Fragment contains a nonsense mutation (ochre) after codon 43. Similar to Streptococcus thermophilus transposase Tnpsth1 UniProt:Q5M4U1 (EMBL:CP000023 (289 aa) fasta scores: E()=7.4e-07, 50.847% id in 59 aa
553482006920	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; cl01839
553482006921	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
553482006922	Peptidase family U32; Region: Peptidase_U32; cl03113
553482006923	HMMPfam hit to PF01136, Peptidase family U32, score 1.3e-131
553482006924	PS01276 Peptidase family U32 signature.
553482006925	Peptidase family U32; Region: Peptidase_U32; cl03113
553482006926	HMMPfam hit to PF01136, Peptidase family U32, score 1.1e-76
553482006927	Helix-turn-helix domains; Region: HTH; cl00088
553482006928	Winged helix-turn helix; Region: HTH_29; pfam13551
553482006929	Helix-turn-helix domains; Region: HTH; cl00088
553482006930	Integrase core domain; Region: rve; cl01316
553482006931	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482006932	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006933	Protein of unknown function (DUF3270); Region: DUF3270; pfam11674
553482006934	2 transmembrane helices predicted for SEQ1534 by TMHMM2.0 at aa 60-82 and 87-109
553482006935	YtxH-like protein; Region: YtxH; cl02079
553482006936	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
553482006937	HMMPfam hit to PF06103, Bacterial protein of unknown function (DUF94, score 1.5e-45
553482006938	1 transmembrane helix predicted for SEQ1536 by TMHMM2.0 at aa 4-26
553482006939	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
553482006940	HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 2.5e-133
553482006941	5 transmembrane helices predicted for SEQ1537 by TMHMM2.0 at aa 15-33, 46-68, 83-105, 165-187 and 224-246
553482006942	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006943	PS01311 Prolipoprotein diacylglyceryl transferase signature.
553482006944	DRTGG domain; Region: DRTGG; cl12147
553482006945	HPr kinase/phosphorylase; Provisional; Region: PRK05428
553482006946	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
553482006947	Hpr binding site; other site
553482006948	active site
553482006949	homohexamer subunit interaction site [polypeptide binding]; other site
553482006950	HMMPfam hit to PF07475, HPr Serine kinase C-terminus, score 2.6e-70
553482006951	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006952	HMMPfam hit to PF02603, HPr Serine kinase N terminus, score 3.7e-28
553482006953	PspC domain; Region: PspC; cl00864
553482006954	HMMPfam hit to PF04024, PspC domain, score 1.4e-21
553482006955	1 transmembrane helix predicted for SEQ1540 by TMHMM2.0 at aa 34-56
553482006956	hypothetical protein; Provisional; Region: PRK04351
553482006957	SprT homologues; Region: SprT; cl01182
553482006958	HMMPfam hit to PF03926, metallopeptidase (SprT family), score 6.8e-65
553482006959	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
553482006960	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
553482006961	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination.  HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes...; Region: RuvC_resolvase; cl00243
553482006962	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
553482006963	RNA binding site [nucleotide binding]; other site
553482006964	HMMPfam hit to PF00575, S1 RNA binding domain, score 2.1e-19
553482006965	Predicted helix-turn-helix motif with score 1224.000, SD 3.36 at aa 583-604, sequence VNLEEMAEQLTLGQETLKDIIA
553482006966	PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
553482006967	Predicted helix-turn-helix motif with score 1623.000, SD 4.71 at aa 4-25, sequence MNHQNISEALGVTPKQISQVLT
553482006968	phosphate transporter ATP-binding protein; Provisional; Region: PRK14240
553482006969	Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient.  The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes.  The PstS protein...; Region: ABC_PstB_phosphate_transporter; cd03260
553482006970	Walker A/P-loop; other site
553482006971	ATP binding site [chemical binding]; other site
553482006972	Q-loop/lid; other site
553482006973	ABC transporter signature motif; other site
553482006974	Walker B; other site
553482006975	D-loop; other site
553482006976	H-loop/switch region; other site
553482006977	HMMPfam hit to PF00005, ABC transporter, score 5.3e-59
553482006978	PS00211 ABC transporters family signature.
553482006979	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006980	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
553482006981	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006982	dimer interface [polypeptide binding]; other site
553482006983	conserved gate region; other site
553482006984	putative PBP binding loops; other site
553482006985	ABC-ATPase subunit interface; other site
553482006986	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-23
553482006987	6 transmembrane helices predicted for SEQ1545 by TMHMM2.0 at aa 9-30, 60-82, 95-117, 122-144, 176-198 and 241-263
553482006988	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006989	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
553482006990	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006991	dimer interface [polypeptide binding]; other site
553482006992	conserved gate region; other site
553482006993	putative PBP binding loops; other site
553482006994	ABC-ATPase subunit interface; other site
553482006995	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
553482006996	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-11
553482006997	6 transmembrane helices predicted for SEQ1546 by TMHMM2.0 at aa 13-35, 74-96, 109-131, 141-163, 201-223 and 258-280
553482006998	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482006999	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482007000	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007001	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
553482007002	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007003	dimer interface [polypeptide binding]; other site
553482007004	phosphorylation site [posttranslational modification]
553482007005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007006	ATP binding site [chemical binding]; other site
553482007007	Mg2+ binding site [ion binding]; other site
553482007008	G-X-G motif; other site
553482007009	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.7e-43
553482007010	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.7e-19
553482007011	2 transmembrane helices predicted for SEQ1548 by TMHMM2.0 at aa 7-24 and 29-51
553482007012	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007013	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007014	active site
553482007015	phosphorylation site [posttranslational modification]
553482007016	intermolecular recognition site; other site
553482007017	dimerization interface [polypeptide binding]; other site
553482007018	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007019	DNA binding site [nucleotide binding]
553482007020	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.7e-26
553482007021	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-43
553482007022	Predicted permeases [General function prediction only]; Region: COG0701
553482007023	Predicted permease; Region: DUF318; pfam03773
553482007024	HMMPfam hit to PF03773, Predicted permease, score 9.4e-121
553482007025	7 transmembrane helices predicted for SEQ1551 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 122-144, 211-233, 240-262 and 277-299
553482007026	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007027	Domain of unknown function (DUF1980); Region: DUF1980; cl01492
553482007028	3 transmembrane helices predicted for SEQ1552 by TMHMM2.0 at aa 7-24, 39-61 and 82-104
553482007029	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
553482007030	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.2e-155
553482007031	PS00572 Glycosyl hydrolases family 1 active site.
553482007032	PS00653 Glycosyl hydrolases family 1 N-terminal signature.
553482007033	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
553482007034	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482007035	active site turn [active]
553482007036	phosphorylation site [posttranslational modification]
553482007037	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482007038	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
553482007039	HPr interaction site; other site
553482007040	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482007041	active site
553482007042	phosphorylation site [posttranslational modification]
553482007043	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.1e-63
553482007044	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482007045	9 transmembrane helices predicted for SEQ1554 by TMHMM2.0 at aa 106-128, 143-165, 172-194, 204-226, 246-268, 283-305, 352-374, 389-411 and 424-446
553482007046	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.3e-33
553482007047	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007048	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 1.8e-15
553482007049	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482007050	transcriptional antiterminator BglG; Provisional; Region: PRK09772
553482007051	CAT RNA binding domain; Region: CAT_RBD; cl03904
553482007052	PRD domain; Region: PRD; cl15445
553482007053	PRD domain; Region: PRD; cl15445
553482007054	HMMPfam hit to PF00874, PRD domain, score 4.7e-15
553482007055	HMMPfam hit to PF00874, PRD domain, score 5.6e-20
553482007056	PS00654 Transcriptional antiterminators bglG family signature.
553482007057	HMMPfam hit to PF03123, CAT RNA binding domain, score 2.3e-29
553482007058	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK13108
553482007059	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
553482007060	SRP54-type protein, helical bundle domain; Region: SRP54_N; cl03758
553482007061	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
553482007062	P loop; other site
553482007063	GTP binding site [chemical binding]; other site
553482007064	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 1.1e-112
553482007065	PS00300 SRP54-type proteins GTP-binding domain signature.
553482007066	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007067	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 5.4e-15
553482007068	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482007069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007070	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00012
553482007071	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 3.6e-80
553482007072	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.3e-08
553482007073	PS01228 Hypothetical cof family signature 1.
553482007074	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007075	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482007076	active site
553482007077	motif I; other site
553482007078	motif II; other site
553482007079	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007080	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.0012
553482007081	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 7.6e-71
553482007082	1 transmembrane helix predicted for SEQ1559 by TMHMM2.0 at aa 5-22
553482007083	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482007084	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482007085	Walker A/P-loop; other site
553482007086	ATP binding site [chemical binding]; other site
553482007087	Q-loop/lid; other site
553482007088	ABC transporter signature motif; other site
553482007089	Walker B; other site
553482007090	D-loop; other site
553482007091	H-loop/switch region; other site
553482007092	HMMPfam hit to PF00005, ABC transporter, score 1.7e-48
553482007093	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007094	8 transmembrane helices predicted for SEQ1561 by TMHMM2.0 at aa 7-25, 138-160, 189-211, 221-243, 263-282, 559-581, 602-624 and 628-647
553482007095	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007096	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is 'interfacial activation', the process of becoming...; Region: Lipase; cl14883
553482007097	nucleophilic elbow; other site
553482007098	catalytic triad; other site
553482007099	1 transmembrane helix predicted for SEQ1565 by TMHMM2.0 at aa 10-29
553482007100	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
553482007101	Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function.  Barmotin belongs to the SMC protein family. SMC proteins are large; Region: ABC_SMC_barmotin; cd03278
553482007102	Walker A/P-loop; other site
553482007103	ATP binding site [chemical binding]; other site
553482007104	Q-loop/lid; other site
553482007105	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; cl05797
553482007106	Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function.  Barmotin belongs to the SMC protein family. SMC proteins are large; Region: ABC_SMC_barmotin; cd03278
553482007107	ABC transporter signature motif; other site
553482007108	Walker B; other site
553482007109	D-loop; other site
553482007110	H-loop/switch region; other site
553482007111	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 9.2e-110
553482007112	HMMPfam hit to PF06470, SMC proteins Flexible Hinge Domain, score 3.9e-28
553482007113	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007114	ribonuclease III; Reviewed; Region: rnc; PRK00102
553482007115	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
553482007116	dimerization interface [polypeptide binding]; other site
553482007117	active site
553482007118	metal binding site [ion binding]; metal-binding site
553482007119	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
553482007120	dsRNA binding site [nucleotide binding]; other site
553482007121	HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 2.8e-18
553482007122	HMMPfam hit to PF00636, RNase3 domain, score 9.7e-47
553482007123	PS00517 Ribonuclease III family signature.
553482007124	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482007125	Helix-turn-helix domains; Region: HTH; cl00088
553482007126	Helix-turn-helix domains; Region: HTH; cl00088
553482007127	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482007128	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482007129	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 5.2e-45
553482007130	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 1.5e-21
553482007131	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 6.1e-10
553482007132	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482007133	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482007134	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 1.3e-52
553482007135	PS00018 EF-hand calcium-binding domain.
553482007136	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 3e-19
553482007137	PS00092 N-6 Adenine-specific DNA methylases signature.
553482007138	Restriction endonuclease FokI, recognition domain; Region: FokI_N; pfam02981
553482007139	Restriction endonuclease FokI, catalytic domain; Region: FokI_C; pfam02980
553482007140	Restriction endonuclease FokI, C terminal; Region: Endonuc-FokI_C; pfam09254
553482007141	HMMPfam hit to PF02980, Restriction endonuclease FokI, catalytic dom, score 1.2e-32
553482007142	putative transposase OrfB; Reviewed; Region: PHA02517
553482007143	HTH-like domain; Region: HTH_21; pfam13276
553482007144	Integrase core domain; Region: rve; cl01316
553482007145	Integrase core domain; Region: rve_3; cl15866
553482007146	HMMPfam hit to PF00665, Integrase core domain, score 1.8e-37
553482007147	CDS contains a frameshift after codon 142. Insertion of additional bases at the frameshift has introduced 11 extra residues. Similar to Streptococcus pyogenes serotype M3 transposase. UniProt:Q1J650 (EMBL:CP000262 (177 aa) fasta scores: E()=2.8e-36, 76.923% id in 182 aa
553482007148	HMMPfam hit to PF02178, no description, score 0.21
553482007149	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007150	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
553482007151	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
553482007152	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
553482007153	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007154	dimer interface [polypeptide binding]; other site
553482007155	phosphorylation site [posttranslational modification]
553482007156	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007157	ATP binding site [chemical binding]; other site
553482007158	Mg2+ binding site [ion binding]; other site
553482007159	G-X-G motif; other site
553482007160	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.2e-40
553482007161	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.5e-20
553482007162	HMMPfam hit to PF00989, PAS fold, score 9.9e-08
553482007163	1 transmembrane helix predicted for SEQ1576 by TMHMM2.0 at aa 5-27
553482007164	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007165	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007166	active site
553482007167	phosphorylation site [posttranslational modification]
553482007168	intermolecular recognition site; other site
553482007169	dimerization interface [polypeptide binding]; other site
553482007170	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007171	DNA binding site [nucleotide binding]
553482007172	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.7e-24
553482007173	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.3e-42
553482007174	Protein of unknown function (DUF3114); Region: DUF3114; pfam11311
553482007175	acyl-CoA synthetase; Validated; Region: PRK07638
553482007176	AMP-binding enzyme; Region: AMP-binding; cl15778
553482007177	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007178	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
553482007179	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
553482007180	dimer interface [polypeptide binding]; other site
553482007181	active site
553482007182	HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 3.1e-19
553482007183	1 transmembrane helix predicted for SEQ1580 by TMHMM2.0 at aa 311-333
553482007184	HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.2e-15
553482007185	Predicted helix-turn-helix motif with score 1100.000, SD 2.93 at aa 148-169, sequence AGAERVAQAYQMTPSQLNQWTL
553482007186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007187	Helix-turn-helix domains; Region: HTH; cl00088
553482007188	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007189	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007190	HMMPfam hit to PF02178, no description, score 0.21
553482007191	putative transposase OrfB; Reviewed; Region: PHA02517
553482007192	HTH-like domain; Region: HTH_21; pfam13276
553482007193	Integrase core domain; Region: rve; cl01316
553482007194	Integrase core domain; Region: rve_3; cl15866
553482007195	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007196	gene remnant. CDS is truncated by the insertion of the downstream IS element and subsequent deletion events. Similar to the N-terminal region of Streptococcus pyogenes lantibiotic transport ATP-binding protein Srtf UniProt:P0C0E2 (EMBL:AB030831 (229 aa) fasta scores: E()=2.6e-06, 44.554% id in 101 aa
553482007197	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007198	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007199	dimer interface [polypeptide binding]; other site
553482007200	phosphorylation site [posttranslational modification]
553482007201	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007202	ATP binding site [chemical binding]; other site
553482007203	Mg2+ binding site [ion binding]; other site
553482007204	G-X-G motif; other site
553482007205	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.5e-14
553482007206	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-12
553482007207	2 transmembrane helices predicted for SEQ1586 by TMHMM2.0 at aa 20-42 and 149-171
553482007208	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007209	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007210	active site
553482007211	phosphorylation site [posttranslational modification]
553482007212	intermolecular recognition site; other site
553482007213	dimerization interface [polypeptide binding]; other site
553482007214	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007215	DNA binding site [nucleotide binding]
553482007216	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.6e-19
553482007217	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-32
553482007218	Peptidase S8 family domain in Lantiobiotic (lanthionine-containing antibiotics) specific proteases; Region: Peptidases_S8_Lantibiotic_specific_protease; cd07482
553482007219	active site
553482007220	catalytic triad [active]
553482007221	HMMPfam hit to PF00082, Subtilase family, score 5.8e-29
553482007222	PS00138 Serine proteases, subtilase family, serine active site.
553482007223	PS00136 Serine proteases, subtilase family, aspartic acid active site.
553482007224	PS00430 TonB-dependent receptor proteins signature 1.
553482007226	gene remnant. Fragment contains nonsense and frameshift mutations
553482007227	gene remnant. Similar to N-terminal region of Streptococcus suis transposase OrfA UniProt:Q300F6 (EMBL:AAFA02000034 (178 aa) fasta scores: E()=4.4, 39.535% id in 43 aa
553482007228	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
553482007229	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
553482007230	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469
553482007231	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
553482007232	active site
553482007233	dimer interface [polypeptide binding]; other site
553482007234	motif 1; other site
553482007235	motif 2; other site
553482007236	motif 3; other site
553482007237	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
553482007238	anticodon binding site; other site
553482007239	HMMPfam hit to PF03129, Anticodon binding domain, score 3e-29
553482007240	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 2.6e-55
553482007241	HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase se, score 4.8e-25
553482007242	HMMPfam hit to PF02824, TGS domain, score 1.1e-14
553482007243	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482007244	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
553482007245	putative ADP-binding pocket [chemical binding]; other site
553482007246	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.7e-25
553482007247	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
553482007248	HMMPfam hit to PF00534, Glycosyl transferases group, score 3.3e-09
553482007249	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
553482007250	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
553482007251	active site
553482007252	Na/Ca binding site [ion binding]; other site
553482007253	catalytic site [active]
553482007254	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
553482007255	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 3.8e-69
553482007256	catabolite control protein A; Region: ccpA; TIGR01481
553482007257	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482007258	DNA binding site [nucleotide binding]
553482007259	domain linker motif; other site
553482007260	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
553482007261	dimerization interface [polypeptide binding]; other site
553482007262	effector binding site; other site
553482007263	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 6.6e-07
553482007264	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 5.4e-13
553482007265	Predicted helix-turn-helix motif with score 2166.000, SD 6.56 at aa 7-28, sequence ITIYDVAREAGVSMATVSRVVN
553482007266	PS00356 Bacterial regulatory proteins, lacI family signature.
553482007267	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
553482007268	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
553482007269	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
553482007270	active site
553482007271	HMMPfam hit to PF00557, metallopeptidase family M24, score 1.6e-74
553482007272	PS00491 Aminopeptidase P and proline dipeptidase signature.
553482007273	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482007274	The MRP (Mutidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export.  They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins.  The ABCC subfamily contains transporters with a...; Region: ABCC_MRP_Like; cd03228
553482007275	Walker A/P-loop; other site
553482007276	ATP binding site [chemical binding]; other site
553482007277	Q-loop/lid; other site
553482007278	ABC transporter signature motif; other site
553482007279	Walker B; other site
553482007280	D-loop; other site
553482007281	H-loop/switch region; other site
553482007282	HMMPfam hit to PF00005, ABC transporter, score 5.8e-36
553482007283	PS00211 ABC transporters family signature.
553482007284	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007285	5 transmembrane helices predicted for SEQ1598 by TMHMM2.0 at aa 13-35, 50-72, 120-142, 147-169 and 230-252
553482007286	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482007287	non-specific DNA binding site [nucleotide binding]; other site
553482007288	salt bridge; other site
553482007289	sequence-specific DNA binding site [nucleotide binding]; other site
553482007290	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482007291	HMMPfam hit to PF01381, Helix-turn-helix, score 4.5e-08
553482007292	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
553482007293	dimer interface [polypeptide binding]; other site
553482007294	FMN binding site [chemical binding]; other site
553482007295	HMMPfam hit to PF00881, Nitroreductase family, score 1.6e-47
553482007296	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
553482007297	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
553482007298	Ligand binding site; other site
553482007299	Putative Catalytic site; other site
553482007300	DXD motif; other site
553482007301	HMMPfam hit to PF00535, Glycosyl transferase family, score 1.9e-31
553482007302	2 transmembrane helices predicted for SEQ1601 by TMHMM2.0 at aa 230-252 and 264-286
553482007303	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
553482007304	SmpB-tmRNA interface; other site
553482007305	HMMPfam hit to PF01668, SmpB protein, score 2.1e-36
553482007306	PS01317 Protein smpB signature.
553482007307	ribonuclease R; Region: RNase_R; TIGR02063
553482007308	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482007309	RNB domain; Region: RNB; pfam00773
553482007310	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase play an important...; Region: S1_RNase_R; cd04471
553482007311	RNA binding site [nucleotide binding]; other site
553482007312	HMMPfam hit to PF00575, S1 RNA binding domain, score 1.7e-12
553482007313	PS01175 Ribonuclease II family signature.
553482007314	HMMPfam hit to PF00773, RNB-like protein, score 2.3e-97
553482007315	HMMPfam hit to PF08206, Ribonuclease B OB domain, score 2.5e-20
553482007316	Preprotein translocase SecG subunit; Region: SecG; cl09123
553482007317	HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 1.8e-30
553482007318	2 transmembrane helices predicted for SEQ1604 by TMHMM2.0 at aa 5-22 and 53-75
553482007319	Ribosomal protein L33; Region: Ribosomal_L33; cl00383
553482007320	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482007321	TQXA domain; Region: TQXA_dom; TIGR03934
553482007322	2 transmembrane helices predicted for SEQ1606 by TMHMM2.0 at aa 9-31 and 603-622
553482007323	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.1e-13
553482007324	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.5e-09
553482007325	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.8e-14
553482007326	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 4.9e-15
553482007327	CDS contains a nonsense mutation (ochre) after codon 214
553482007328	1 transmembrane helix predicted for SEQ1607 by TMHMM2.0 at aa 9-31
553482007329	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.7e-14
553482007330	1 transmembrane helix predicted for SEQ1608 by TMHMM2.0 at aa 72-91
553482007331	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
553482007332	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
553482007333	CoA-binding site [chemical binding]; other site
553482007334	ATP-binding [chemical binding]; other site
553482007335	HMMPfam hit to PF01121, Dephospho-CoA kinase, score 7.7e-49
553482007336	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007337	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
553482007338	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
553482007339	DNA binding site [nucleotide binding]
553482007340	catalytic residue [active]
553482007341	H2TH interface [polypeptide binding]; other site
553482007342	putative catalytic residues [active]
553482007343	turnover-facilitating residue; other site
553482007344	intercalation triad [nucleotide binding]; other site
553482007345	8OG recognition residue [nucleotide binding]; other site
553482007346	putative reading head residues; other site
553482007347	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
553482007348	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
553482007349	HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 2e-10
553482007350	HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycosylase H2, score 1.9e-42
553482007351	HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase N-, score 8.3e-51
553482007352	Beta-galactosidase; Region: Glyco_hydro_42; cl03154
553482007353	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 6.4e-175
553482007354	HMMPfam hit to PF02449, Beta-galactosidase, score 0.00029
553482007355	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482007356	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
553482007357	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
553482007358	active site
553482007359	catalytic residues [active]
553482007360	Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; Region: LamG; cl00102
553482007361	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
553482007362	catalytic site [active]
553482007363	Asp-box motif; other site
553482007364	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
553482007365	Asp-box motif; other site
553482007366	catalytic site [active]
553482007367	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.4
553482007368	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.038
553482007369	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.51
553482007370	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.085
553482007371	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 1.4e-19
553482007372	HMMPfam hit to PF02018, Carbohydrate binding domain, score 0.00028
553482007373	1 transmembrane helix predicted for SEQ1612 by TMHMM2.0 at aa 20-42
553482007374	PS00099 Thiolases active site.
553482007375	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.9e-06
553482007376	CDS contains a frameshift around codon 313. Similar to Listeria monocytogenes PTS system, cellobiose-specific, IIC component UniProt:Q4ETL0 (EMBL:AADQ01000007 (454 aa) fasta scores: E()=2.5e-72, 47.556% id in 450 aa
553482007377	2 transmembrane helices predicted for SEQ1613 by TMHMM2.0 at aa 43-65 and 95-114
553482007378	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3.5e-20
553482007379	6 transmembrane helices predicted for SEQ1614 by TMHMM2.0 at aa 31-53, 73-95, 107-129, 173-192, 212-231 and 254-276
553482007380	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482007381	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482007382	10 transmembrane helices predicted for SEQ1615 by TMHMM2.0 at aa 34-56, 76-93, 100-122, 137-159, 180-202, 217-239, 241-263, 293-312, 350-372 and 402-424
553482007383	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.2e-73
553482007384	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482007385	active site
553482007386	methionine cluster; other site
553482007387	phosphorylation site [posttranslational modification]
553482007388	metal binding site [ion binding]; metal-binding site
553482007389	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 1.6e-39
553482007390	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482007391	active site
553482007392	P-loop; other site
553482007393	phosphorylation site [posttranslational modification]
553482007394	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 4.2e-33
553482007395	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482007396	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482007397	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
553482007398	Predicted helix-turn-helix motif with score 1378.000, SD 3.88 at aa 23-44, sequence ISRIDISKLTHITPATVGAITK
553482007399	HMMPfam hit to PF00480, ROK family, score 5e-09
553482007400	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
553482007401	nudix motif; other site
553482007402	HMMPfam hit to PF00293, NUDIX domain, score 3.5e-19
553482007403	PS00893 mutT domain signature.
553482007404	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007405	Helix-turn-helix domains; Region: HTH; cl00088
553482007406	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007407	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007408	HMMPfam hit to PF02178, no description, score 0.21
553482007409	putative transposase OrfB; Reviewed; Region: PHA02517
553482007410	HTH-like domain; Region: HTH_21; pfam13276
553482007411	Integrase core domain; Region: rve; cl01316
553482007412	Integrase core domain; Region: rve_3; cl15866
553482007413	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007414	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
553482007415	Na+-H+ antiporter family; Region: Na_H_antiport_2; cl15264
553482007416	HMMPfam hit to PF02447, GntP family permease, score 7.4e-05
553482007417	12 transmembrane helices predicted for SEQ1623 by TMHMM2.0 at aa 4-21, 28-50, 65-87, 108-130, 150-172, 185-207, 239-261, 268-285, 307-329, 342-364, 387-409 and 422-441
553482007418	HMMPfam hit to PF03600, Citrate transporter, score 1.7e-37
553482007419	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007420	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482007421	3-hydroxybutyrate dehydrogenase; Region: PHB_DH; TIGR01963
553482007422	NAD(P) binding site [chemical binding]; other site
553482007423	active site
553482007424	HMMPfam hit to PF00106, short chain dehydrogenase, score 5e-21
553482007425	PS00061 Short-chain dehydrogenases/reductases family signature.
553482007426	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482007427	HMMPfam hit to PF01144, Coenzyme A transferase, score 4.1e-48
553482007428	PS01274 CoA transferases signature 2.
553482007429	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482007430	HMMPfam hit to PF01144, Coenzyme A transferase, score 1e-77
553482007431	PS01273 CoA transferases signature 1.
553482007432	putative acyltransferase; Provisional; Region: PRK05790
553482007433	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
553482007434	dimer interface [polypeptide binding]; other site
553482007435	active site
553482007436	HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 4e-70
553482007437	PS00099 Thiolases active site.
553482007438	PS00737 Thiolases signature 2.
553482007439	HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 9.8e-154
553482007440	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
553482007441	Helix-turn-helix domains; Region: HTH; cl00088
553482007442	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482007443	dimerization interface [polypeptide binding]; other site
553482007444	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.1e-09
553482007445	Predicted helix-turn-helix motif with score 1789.000, SD 5.28 at aa 17-38, sequence FNLSRTAQQLYISQPTLSIMIN
553482007446	HMMPfam hit to PF03466, LysR substrate binding domain, score 5.8e-12
553482007447	6 transmembrane helices predicted for SEQ1629 by TMHMM2.0 at aa 17-39, 154-176, 208-230, 265-287, 294-316 and 353-375
553482007448	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482007449	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482007450	ABC-type multidrug transport system, ATPase component.  The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily.  ABC transporters are a large family of proteins involved in the...; Region: ABC_drug_resistance_like; cd03264
553482007451	Walker A/P-loop; other site
553482007452	ATP binding site [chemical binding]; other site
553482007453	Q-loop/lid; other site
553482007454	ABC transporter signature motif; other site
553482007455	Walker B; other site
553482007456	D-loop; other site
553482007457	H-loop/switch region; other site
553482007458	HMMPfam hit to PF00005, ABC transporter, score 4.1e-52
553482007459	PS00211 ABC transporters family signature.
553482007460	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007461	LytTr DNA-binding domain; Region: LytTR; cl04498
553482007462	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M6 hypothetical protein UniProt:Q5XDG1 (EMBL:CP000003 (84 aa) fasta scores: E()=3.8e-11, 66.667% id in 48 aa
553482007463	GTPase Era; Reviewed; Region: era; PRK00089
553482007464	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
553482007465	G1 box; other site
553482007466	GTP/Mg2+ binding site [chemical binding]; other site
553482007467	Switch I region; other site
553482007468	G2 box; other site
553482007469	Switch II region; other site
553482007470	G3 box; other site
553482007471	G4 box; other site
553482007472	G5 box; other site
553482007473	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cl00098
553482007474	HMMPfam hit to PF07650, KH domain, score 7.1e-29
553482007475	HMMPfam hit to PF01926, GTPase of unknown function, score 6.3e-40
553482007476	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007477	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; cl00526
553482007478	2 transmembrane helices predicted for SEQ1634 by TMHMM2.0 at aa 41-63 and 103-125
553482007479	HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 3.2e-48
553482007480	PS01069 Prokaryotic diacylglycerol kinase signature.
553482007481	Uncharacterized protein family UPF0054; Region: UPF0054; cl00402
553482007482	HMMPfam hit to PF02130, Uncharacterized protein family UPF0054, score 8.4e-26
553482007483	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482007484	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482007485	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-07
553482007486	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
553482007487	putative uracil binding site [chemical binding]; other site
553482007488	putative active site [active]
553482007489	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482007490	HMMPfam hit to PF02562, PhoH-like protein, score 1.6e-136
553482007491	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007492	Protein of unknown function (DUF1250); Region: DUF1250; cl11485
553482007493	HMMPfam hit to PF06855, Protein of unknown function (DUF1250), score 1.1e-27
553482007494	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
553482007495	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 2.5e-80
553482007496	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
553482007497	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482007498	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482007499	ribosome recycling factor; Reviewed; Region: frr; PRK00083
553482007500	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are 'recycled' and ready for another round of...; Region: RRF; cd00520
553482007501	hinge region; other site
553482007502	HMMPfam hit to PF01765, Ribosome recycling factor, score 9.6e-94
553482007503	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
553482007504	putative nucleotide binding site [chemical binding]; other site
553482007505	uridine monophosphate binding site [chemical binding]; other site
553482007506	homohexameric interface [polypeptide binding]; other site
553482007507	HMMPfam hit to PF00696, Amino acid kinase family, score 3.6e-59
553482007508	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482007509	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482007510	Walker A/P-loop; other site
553482007511	ATP binding site [chemical binding]; other site
553482007512	Q-loop/lid; other site
553482007513	ABC transporter signature motif; other site
553482007514	Walker B; other site
553482007515	D-loop; other site
553482007516	H-loop/switch region; other site
553482007517	HMMPfam hit to PF00005, ABC transporter, score 2.3e-53
553482007518	PS00211 ABC transporters family signature.
553482007519	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007520	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482007521	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
553482007522	Walker A/P-loop; other site
553482007523	ATP binding site [chemical binding]; other site
553482007524	Q-loop/lid; other site
553482007525	ABC transporter signature motif; other site
553482007526	Walker B; other site
553482007527	D-loop; other site
553482007528	H-loop/switch region; other site
553482007529	HMMPfam hit to PF00005, ABC transporter, score 2.5e-38
553482007530	PS00211 ABC transporters family signature.
553482007531	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007532	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
553482007533	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
553482007534	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007535	dimer interface [polypeptide binding]; other site
553482007536	conserved gate region; other site
553482007537	putative PBP binding loops; other site
553482007538	ABC-ATPase subunit interface; other site
553482007539	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-28
553482007540	6 transmembrane helices predicted for SEQ1646 by TMHMM2.0 at aa 5-27, 70-92, 99-118, 122-144, 189-211 and 231-253
553482007541	nickel ABC transporter, permease subunit NikB; Region: nickel_nikB; TIGR02789
553482007542	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007543	dimer interface [polypeptide binding]; other site
553482007544	conserved gate region; other site
553482007545	putative PBP binding loops; other site
553482007546	ABC-ATPase subunit interface; other site
553482007547	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.5e-43
553482007548	6 transmembrane helices predicted for SEQ1647 by TMHMM2.0 at aa 5-27, 94-116, 129-151, 166-183, 225-247 and 267-289
553482007549	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
553482007550	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
553482007551	substrate binding site [chemical binding]; other site
553482007552	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.4e-81
553482007553	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007554	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482007555	TQXA domain; Region: TQXA_dom; TIGR03934
553482007556	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.1e-06
553482007557	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 3.3e-15
553482007558	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 3.8e-07
553482007559	1 transmembrane helix predicted for SEQ1649 by TMHMM2.0 at aa 491-510
553482007560	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
553482007561	mRNA/rRNA interface [nucleotide binding]; other site
553482007562	HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family, score 4.7e-117
553482007563	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
553482007564	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
553482007565	23S rRNA interface [nucleotide binding]; other site
553482007566	L7/L12 interface [polypeptide binding]; other site
553482007567	putative thiostrepton binding site; other site
553482007568	L25 interface [polypeptide binding]; other site
553482007569	PS00359 Ribosomal protein L11 signature.
553482007570	HMMPfam hit to PF00298, Ribosomal protein L11, RNA binding do, score 4.1e-41
553482007571	HMMPfam hit to PF03946, Ribosomal protein L11, N-terminal dom, score 5.1e-35
553482007572	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482007573	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482007574	DNA binding site [nucleotide binding]
553482007575	domain linker motif; other site
553482007576	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI family, score 8.9e-13
553482007577	Predicted helix-turn-helix motif with score 2253.000, SD 6.86 at aa 5-26, sequence VTIKDVAREAGVSVATVSYVIN
553482007578	PS00356 Bacterial regulatory proteins, lacI family signature.
553482007579	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
553482007580	3 transmembrane helices predicted for SEQ1653 by TMHMM2.0 at aa 7-29, 58-80 and 93-115
553482007581	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
553482007582	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482007583	Ftsk gamma domain; Region: Ftsk_gamma; cl09645
553482007584	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 5.4e-76
553482007585	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007586	5 transmembrane helices predicted for SEQ1655 by TMHMM2.0 at aa 49-68, 78-100, 107-129, 144-166 and 173-195
553482007587	peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional; Region: PRK10791
553482007588	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
553482007589	active site
553482007590	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007591	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 3e-43
553482007592	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482007593	ABC-ATPase subunit  interface; other site
553482007594	dimer interface [polypeptide binding]; other site
553482007595	putative PBP binding regions; other site
553482007596	7 transmembrane helices predicted for SEQ1658 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 137-159, 179-201, 214-236 and 246-268
553482007597	HMMPfam hit to PF00950, ABC 3 transport family, score 1.2e-127
553482007598	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007599	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
553482007600	ABC component of the metal-type transporters.  This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc.  The ATPases of this group of transporters are very similar to members of...; Region: ABC_Metallic_Cations; cd03235
553482007601	HMMPfam hit to PF00005, ABC transporter, score 8.1e-51
553482007602	PS00211 ABC transporters family signature.
553482007603	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007604	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
553482007605	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
553482007606	metal binding site [ion binding]; metal-binding site
553482007607	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 1.3e-142
553482007608	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007609	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
553482007610	Helix-turn-helix domains; Region: HTH; cl00088
553482007611	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
553482007612	FeoA domain; Region: FeoA; cl00838
553482007613	HMMPfam hit to PF01047, MarR family, score 0.0002
553482007614	HMMPfam hit to PF01325, Iron dependent repressor, N-terminal D, score 1.5e-11
553482007615	Predicted helix-turn-helix motif with score 1322.000, SD 3.69 at aa 22-43, sequence ISNKMVAERMKVSAPAVSEMIK
553482007616	HMMPfam hit to PF02742, Iron dependent repressor, metal bindin, score 8e-23
553482007617	HMMPfam hit to PF04023, FeoA domain, score 1.1e-12
553482007618	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
553482007619	HMMPfam hit to PF01048, Phosphorylase family, score 1.2e-65
553482007620	1 transmembrane helix predicted for SEQ1663 by TMHMM2.0 at aa 61-80
553482007621	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482007622	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
553482007623	dimer interface [polypeptide binding]; other site
553482007624	ADP-ribose binding site [chemical binding]; other site
553482007625	active site
553482007626	nudix motif; other site
553482007627	metal binding site [ion binding]; metal-binding site
553482007628	HMMPfam hit to PF00293, NUDIX domain, score 4.5e-20
553482007629	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
553482007630	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
553482007631	Substrate binding site; other site
553482007632	Mg++ binding site; other site
553482007633	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
553482007634	active site
553482007635	substrate binding site [chemical binding]; other site
553482007636	CoA binding site [chemical binding]; other site
553482007637	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 14
553482007638	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.2
553482007639	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 36
553482007640	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 42
553482007641	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.99
553482007642	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 9.8
553482007643	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 4.2
553482007644	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.6e-10
553482007645	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
553482007646	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482007647	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; cl11611
553482007648	HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.21
553482007649	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 7.5e-34
553482007650	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 1.4e-09
553482007651	CDS contains a nonsense mutation (opal) after codon 50. Similar to Streptococcus agalactiae hypothetical protein UniProt:Q3CZK4 (EMBL:AAJS01000069 (150 aa) fasta scores: E()=3.7e-37, 68.493% id in 146 aa
553482007652	HMMPfam hit to PF06171, Protein of unknown function (DUF984), score 1.1e-62
553482007653	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
553482007654	classical (c) SDRs; Region: SDR_c; cd05233
553482007655	NAD(P) binding site [chemical binding]; other site
553482007656	active site
553482007657	HMMPfam hit to PF00106, short chain dehydrogenase, score 9e-20
553482007658	PS00061 Short-chain dehydrogenases/reductases family signature.
553482007659	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
553482007660	CDS contains a frameshift after codon 33. CDS is intact in Streptococcus zooepidemicus
553482007661	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 7.4e-13
553482007662	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
553482007663	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482007664	active site
553482007665	HIGH motif; other site
553482007666	nucleotide binding site [chemical binding]; other site
553482007667	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
553482007668	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
553482007669	active site
553482007670	KMSKS motif; other site
553482007671	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
553482007672	tRNA binding surface [nucleotide binding]; other site
553482007673	anticodon binding site; other site
553482007674	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
553482007675	HMMPfam hit to PF08264, Anticodon-binding domain, score 2.7e-60
553482007676	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 0
553482007677	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482007678	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
553482007679	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482007680	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482007681	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
553482007682	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-11
553482007683	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; cl11613
553482007684	Predicted helix-turn-helix motif with score 1067.000, SD 2.82 at aa 138-159, sequence WTEAELLALKGIGPATISKLKE
553482007685	Domain of unknown function (DUF1912); Region: DUF1912; pfam08930
553482007686	gene remnan. Similar to an internal region of Streptococcus pyogenes serotype M28 hypothetical exported protein UniProt:Q48S92 (EMBL:CP000056 (452 aa) fasta scores: E()=0.00019, 63.333% id in 30 aa
553482007687	gene remnant. Similar to an internal region of Streptococcus agalactiae DNA-damage-inducible protein J UniProt:Q3DLB5 (EMBL:AAJP01000028 (97 aa) fasta scores: E()=0.0039, 55.000% id in 40 aa
553482007688	NeuB family; Region: NeuB; cl00496
553482007689	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
553482007690	HMMPfam hit to PF00793, DAHP synthetase I family, score 8.8e-84
553482007691	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
553482007692	active site
553482007693	dimer interface [polypeptide binding]; other site
553482007694	metal binding site [ion binding]; metal-binding site
553482007695	HMMPfam hit to PF01761, 3-dehydroquinate synthase, score 6.8e-124
553482007696	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
553482007697	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007698	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
553482007699	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
553482007700	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
553482007701	shikimate binding site; other site
553482007702	NAD(P) binding site [chemical binding]; other site
553482007703	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 9.1e-13
553482007704	PS00579 Ribosomal protein L29 signature.
553482007705	HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 8.8e-43
553482007706	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; cl08371
553482007707	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
553482007708	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; cl15381
553482007709	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 6.1e-08
553482007710	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 0.00056
553482007711	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1e-46
553482007712	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
553482007713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007714	active site
553482007715	phosphorylation site [posttranslational modification]
553482007716	intermolecular recognition site; other site
553482007717	dimerization interface [polypeptide binding]; other site
553482007718	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482007719	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.1e-08
553482007720	PS00041 Bacterial regulatory proteins, araC family signature.
553482007721	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2e-05
553482007722	Predicted helix-turn-helix motif with score 1138.000, SD 3.06 at aa 398-419, sequence LTLKAVSDRLHINGVYLGQRFK
553482007723	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.6e-29
553482007724	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482007725	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
553482007726	Histidine kinase; Region: His_kinase; pfam06580
553482007727	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482007728	HMMPfam hit to PF06580, Histidine kinase, score 1.8e-38
553482007729	HMMPfam hit to PF00672, HAMP domain, score 1.1e-08
553482007730	2 transmembrane helices predicted for SEQ1684 by TMHMM2.0 at aa 26-48 and 280-302
553482007731	Protein of unknown function, DUF624; Region: DUF624; cl02369
553482007732	5 transmembrane helices predicted for SEQ1685 by TMHMM2.0 at aa 20-42, 71-93, 98-120, 140-162 and 169-187
553482007733	HMMPfam hit to PF04854, Protein of unknown function, DUF624, score 5.9e-22
553482007734	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
553482007735	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
553482007736	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 6.4e-09
553482007737	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007738	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
553482007739	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007740	dimer interface [polypeptide binding]; other site
553482007741	ABC-ATPase subunit interface; other site
553482007742	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.7e-09
553482007743	6 transmembrane helices predicted for SEQ1687 by TMHMM2.0 at aa 21-43, 85-107, 120-142, 152-174, 195-217 and 274-293
553482007744	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007745	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
553482007746	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007747	putative PBP binding loops; other site
553482007748	dimer interface [polypeptide binding]; other site
553482007749	ABC-ATPase subunit interface; other site
553482007750	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.2e-10
553482007751	6 transmembrane helices predicted for SEQ1688 by TMHMM2.0 at aa 20-42, 88-110, 123-145, 175-197, 221-243 and 284-306
553482007752	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482007753	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482007754	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
553482007755	HMMPfam hit to PF00480, ROK family, score 1.6e-23
553482007756	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
553482007757	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; cl15460
553482007758	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482007759	HMMPfam hit to PF07971, Glycosyl hydrolase family, score 2e-196
553482007760	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
553482007761	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.6e-94
553482007762	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
553482007763	HMMPfam hit to PF07555, Hyaluronidase, score 9e-160
553482007764	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482007765	DNA-binding site [nucleotide binding]; DNA binding site
553482007766	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482007767	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
553482007768	ligand binding site [chemical binding]; other site
553482007769	dimerization interface [polypeptide binding]; other site
553482007770	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.5e-05
553482007771	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fami, score 3e-22
553482007772	Protein of unknown function (DUF1237); Region: DUF1237; cl15402
553482007773	HMMPfam hit to PF06824, Protein of unknown function (DUF1237), score 2.5e-304
553482007774	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
553482007775	Glycosyl hydrolases family 38 N-terminal domain; Region: Glyco_hydro_38; pfam01074
553482007776	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
553482007777	HMMPfam hit to PF01074, Glycosyl hydrolases family, score 1.6e-28
553482007778	HMMPfam hit to PF07748, Glycosyl hydrolases family 38 C-termi, score 3.8e-07
553482007779	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482007780	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482007781	Walker A/P-loop; other site
553482007782	ATP binding site [chemical binding]; other site
553482007783	Q-loop/lid; other site
553482007784	ABC transporter signature motif; other site
553482007785	Walker B; other site
553482007786	D-loop; other site
553482007787	H-loop/switch region; other site
553482007788	PS00294 Prenyl group binding site (CAAX box).
553482007789	HMMPfam hit to PF00005, ABC transporter, score 1.7e-51
553482007790	PS00211 ABC transporters family signature.
553482007791	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007792	8 transmembrane helices predicted for SEQ1698 by TMHMM2.0 at aa 5-23, 145-167, 196-217, 227-249, 269-288, 558-580, 600-622 and 627-649
553482007793	CDS contains a nonsense mutation (opal) after codon 48. Similar to Streptococcus pyogenes serotype M3 hypothetical exported protein UniProt:Q1JF40 (EMBL:CP000260 (101 aa) fasta scores: E()=4.7e-09, 34.694% id in 98 aa
553482007794	1 transmembrane helix predicted for SEQ1699 by TMHMM2.0 at aa 13-35
553482007795	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
553482007796	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482007797	Coenzyme A binding pocket [chemical binding]; other site
553482007798	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2e-09
553482007799	4 transmembrane helices predicted for SEQ1701 by TMHMM2.0 at aa 13-32, 38-60, 77-99 and 109-131
553482007800	putative transposase OrfB; Reviewed; Region: PHA02517
553482007801	HTH-like domain; Region: HTH_21; pfam13276
553482007802	Integrase core domain; Region: rve; cl01316
553482007803	Integrase core domain; Region: rve_3; cl15866
553482007804	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007805	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007806	Helix-turn-helix domains; Region: HTH; cl00088
553482007807	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007808	HMMPfam hit to PF02178, no description, score 0.21
553482007809	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007810	2 transmembrane helices predicted for SEQ1704 by TMHMM2.0 at aa 5-20 and 41-63
553482007811	1 transmembrane helix predicted for SEQ1705 by TMHMM2.0 at aa 41-63
553482007812	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007813	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482007814	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the 'double-glycine' leader peptides from the precursors of various bacteriocins; Region: Peptidase_C39B; cd02418
553482007815	ABC-type bacteriocin transporter; Region: bacteriocin_ABC; TIGR01193
553482007816	putative active site [active]
553482007817	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
553482007818	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482007819	Walker A/P-loop; other site
553482007820	ATP binding site [chemical binding]; other site
553482007821	Q-loop/lid; other site
553482007822	ABC transporter signature motif; other site
553482007823	Walker B; other site
553482007824	D-loop; other site
553482007825	H-loop/switch region; other site
553482007826	HMMPfam hit to PF03412, Peptidase C39 family, score 2.1e-64
553482007827	4 transmembrane helices predicted for SEQ1709 by TMHMM2.0 at aa 168-190, 202-224, 279-301 and 308-330
553482007828	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 8.3e-63
553482007829	HMMPfam hit to PF00005, ABC transporter, score 4e-52
553482007830	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007831	PS00211 ABC transporters family signature.
553482007832	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
553482007833	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
553482007834	1 transmembrane helix predicted for SEQ1710 by TMHMM2.0 at aa 19-41
553482007835	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007836	Double glycine cleavage site bacteriolysin; Region: Antimicrobial16; pfam08128
553482007837	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482007838	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482007839	7 transmembrane helices predicted for SEQ1711 by TMHMM2.0 at aa 4-22, 29-51, 55-77, 84-106, 121-142, 162-181 and 191-210
553482007840	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482007841	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007842	active site
553482007843	phosphorylation site [posttranslational modification]
553482007844	intermolecular recognition site; other site
553482007845	dimerization interface [polypeptide binding]; other site
553482007846	LytTr DNA-binding domain; Region: LytTR; cl04498
553482007847	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 8.3e-27
553482007848	HMMPfam hit to PF00072, Response regulator receiver domain, score 9.5e-05
553482007849	1 transmembrane helix predicted for SEQ1713 by TMHMM2.0 at aa 42-64
553482007850	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007851	Bacteriocin class II with double-glycine leader peptide; Region: Bacteriocin_IIc; pfam10439
553482007852	2 transmembrane helices predicted for SEQ1714 by TMHMM2.0 at aa 34-56 and 60-82
553482007853	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007854	TRAM domain; Region: TRAM; cl01282
553482007855	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
553482007856	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
553482007857	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482007858	S-adenosylmethionine binding site [chemical binding]; other site
553482007859	HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 7.8e-06
553482007860	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
553482007861	PS01230 RNA methyltransferase trmA family signature 1.
553482007862	HMMPfam hit to PF01938, TRAM domain, score 2.8e-10
553482007863	Predicted helix-turn-helix motif with score 1096.000, SD 2.92 at aa 293-314, sequence WTTQELLDIPGVGKQMIARLKR
553482007864	RecX family; Region: RecX; cl00936
553482007865	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007866	HMMPfam hit to PF02631, RecX family, score 3.8e-05
553482007867	Protein of unknown function (DUF402); Region: DUF402; cl00979
553482007868	HMMPfam hit to PF04167, Protein of unknown function (DUF402), score 1.2e-40
553482007869	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
553482007870	Similar to the N-terminal region of Streptococcus suis IS1167 transposase UniProt:Q2ZXS6 (EMBL:AAFA02000136 (191 aa) fasta scores: E()=2.6e-09, 37.736% id in 106 aa
553482007871	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482007872	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482007873	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482007874	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482007875	RaiA ('ribosome-associated inhibitor A', also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site; Region: RaiA; cd00552
553482007876	30S subunit binding site; other site
553482007877	HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 7.5e-31
553482007878	CDS contains a frameshift after codon 9. Similar to Streptococcus pyogenes serotype M3 comF operon protein ComFC UniProt:Q1JKR1 (EMBL:CP000259 (221 aa) fasta scores: E()=1.8e-42, 54.955% id in 222 aa
553482007879	prophage phiSeq3
553482007880	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482007881	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 2e-08
553482007882	1 transmembrane helix predicted for SEQ1727 by TMHMM2.0 at aa 12-34
553482007883	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482007884	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 2.6e-07
553482007885	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
553482007886	NlpC/P60 family; Region: NLPC_P60; cl11438
553482007887	Bacterial SH3 domain; Region: SH3_3; cl02551
553482007888	HMMPfam hit to PF08460, Bacterial SH3 domain, score 8.5e-09
553482007889	HMMPfam hit to PF05257, CHAP domain, score 1.6e-24
553482007890	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 7e-19
553482007891	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482007892	1 transmembrane helix predicted for SEQ1730 by TMHMM2.0 at aa 21-43
553482007893	1 transmembrane helix predicted for SEQ1731 by TMHMM2.0 at aa 4-26
553482007894	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482007895	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 1.2e-93
553482007896	gp58-like protein; Region: Gp58; pfam07902
553482007897	HMMPfam hit to PF07902, gp58-like protein, score 0
553482007898	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482007899	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.4e-05
553482007900	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482007901	ATP-dependent protease La; Region: lon; TIGR00763
553482007902	Phage-related protein [Function unknown]; Region: COG4722; cl15832
553482007903	Phage tail protein; Region: Sipho_tail; pfam05709
553482007904	Phage-related protein [Function unknown]; Region: COG5412
553482007905	6 transmembrane helices predicted for SEQ1739 by TMHMM2.0 at aa 500-522, 549-571, 586-608, 621-643, 717-739 and 760-782
553482007906	Phage protein; Region: DUF3647; cl10335
553482007907	Phage major tail protein 2; Region: Phage_tail_2; cl11463
553482007908	HMMPfam hit to PF06199, Phage major tail protein, score 2.2e-05
553482007909	Phage major tail protein 2; Region: Phage_tail_2; cl11463
553482007910	HMMPfam hit to PF06199, Phage major tail protein, score 1.3e-24
553482007911	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
553482007912	Bacteriophage protein of unknown function (DUF646); Region: DUF646; cl12124
553482007913	HMMPfam hit to PF07772, TP901-1 ORF40-like protein, score 6.2e-31
553482007914	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
553482007915	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
553482007916	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
553482007917	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
553482007918	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482007919	PS00063 Aldo/keto reductase family active site signature.
553482007920	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
553482007921	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
553482007922	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
553482007923	metal binding triad [ion binding]; metal-binding site
553482007924	HMMPfam hit to PF04233, Phage Mu protein F like protein, score 2.9e-09
553482007925	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
553482007926	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482007927	HMMPfam hit to PF05133, Phage portal protein, SPP1 Gp6-like, score 1.1e-123
553482007928	Phage terminase large subunit; Region: Terminase_3; cl12054
553482007929	Terminase-like family; Region: Terminase_6; pfam03237
553482007930	HMMPfam hit to PF04466, Phage terminase large subunit, score 2.8e-92
553482007931	HMMPfam hit to PF07570, Protein of unknown function (DUF1545), score 9.7e-21
553482007932	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007933	putative transposase OrfB; Reviewed; Region: PHA02517
553482007934	HTH-like domain; Region: HTH_21; pfam13276
553482007935	Integrase core domain; Region: rve; cl01316
553482007936	Integrase core domain; Region: rve_3; cl15866
553482007937	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482007938	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007939	Helix-turn-helix domains; Region: HTH; cl00088
553482007940	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007941	HMMPfam hit to PF02178, no description, score 0.21
553482007942	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007943	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482007944	non-specific DNA binding site [nucleotide binding]; other site
553482007945	salt bridge; other site
553482007946	sequence-specific DNA binding site [nucleotide binding]; other site
553482007947	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482007948	Catalytic site [active]
553482007949	Predicted helix-turn-helix motif with score 1334.000, SD 3.73 at aa 32-53, sequence TKQVELSKATGIPPSTLTGYVK
553482007950	HMMPfam hit to PF00717, Peptidase S24-like, score 5.4e-17
553482007951	Domain of unknown function (DUF4041); Region: DUF4041; pfam13250
553482007952	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
553482007953	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
553482007954	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
553482007955	catalytic residues [active]
553482007956	catalytic nucleophile [active]
553482007957	Presynaptic Site I dimer interface [polypeptide binding]; other site
553482007958	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
553482007959	Synaptic Flat tetramer interface [polypeptide binding]; other site
553482007960	Synaptic Site I dimer interface [polypeptide binding]; other site
553482007961	DNA binding site [nucleotide binding]
553482007962	Recombinase; Region: Recombinase; pfam07508
553482007963	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
553482007964	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 2.9e-31
553482007965	PS00397 Site-specific recombinases active site.
553482007966	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007967	HMMPfam hit to PF07508, Recombinase, score 1.4e-25
553482007968	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0037
553482007969	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007970	Uncharacterized conserved protein [Function unknown]; Region: COG1739
553482007971	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
553482007972	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
553482007973	HMMPfam hit to PF01205, Uncharacterized protein family UPF0029, score 2.1e-57
553482007974	PS00910 Uncharacterized protein family UPF0029 signature.
553482007975	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
553482007976	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
553482007977	dimer interface [polypeptide binding]; other site
553482007978	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482007979	catalytic residue [active]
553482007980	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.2e-113
553482007981	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
553482007982	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482007983	RNA binding site [nucleotide binding]; other site
553482007984	HMMPfam hit to PF00575, S1 RNA binding domain, score 5.7e-15
553482007985	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482007986	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007987	active site
553482007988	motif I; other site
553482007989	motif II; other site
553482007990	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
553482007991	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
553482007992	peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional; Region: PRK10791
553482007993	active site
553482007994	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 9.6e-53
553482007995	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
553482007996	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.0036
553482007997	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 5.5e-56
553482007998	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0028
553482007999	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
553482008000	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482008001	active site
553482008002	phosphorylation site [posttranslational modification]
553482008003	intermolecular recognition site; other site
553482008004	dimerization interface [polypeptide binding]; other site
553482008005	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
553482008006	DNA binding residues [nucleotide binding]
553482008007	dimerization interface [polypeptide binding]; other site
553482008008	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.8e-23
553482008009	PS00622 Bacterial regulatory proteins, luxR family signature.
553482008010	HMMPfam hit to PF00072, Response regulator receiver domain, score 7.6e-28
553482008011	Histidine kinase; Region: HisKA_3; pfam07730
553482008012	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482008013	ATP binding site [chemical binding]; other site
553482008014	Mg2+ binding site [ion binding]; other site
553482008015	G-X-G motif; other site
553482008016	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.3e-13
553482008017	HMMPfam hit to PF07730, Histidine kinase, score 1.1e-22
553482008018	2 transmembrane helices predicted for SEQ1772 by TMHMM2.0 at aa 7-25 and 45-67
553482008019	Predicted membrane protein [Function unknown]; Region: COG4758
553482008020	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
553482008021	3 transmembrane helices predicted for SEQ1773 by TMHMM2.0 at aa 7-24, 28-45 and 52-84
553482008022	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
553482008023	Catalytic domain of Protein Kinases; Region: PKc; cd00180
553482008024	active site
553482008025	ATP binding site [chemical binding]; other site
553482008026	substrate binding site [chemical binding]; other site
553482008027	activation loop (A-loop); other site
553482008028	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
553482008029	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
553482008030	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
553482008031	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
553482008032	HMMPfam hit to PF03793, PASTA domain, score 6.6e-09
553482008033	HMMPfam hit to PF03793, PASTA domain, score 8.9e-10
553482008034	HMMPfam hit to PF03793, PASTA domain, score 9.2e-11
553482008035	1 transmembrane helix predicted for SEQ1774 by TMHMM2.0 at aa 342-364
553482008036	HMMPfam hit to PF07714, Protein tyrosine kinase, score 6.7e-20
553482008037	HMMPfam hit to PF00069, Protein kinase domain, score 4.1e-55
553482008038	HMMPfam hit to PF01163, RIO1 family, score 0.00073
553482008039	PS00108 Serine/Threonine protein kinases active-site signature.
553482008040	PS00107 Protein kinases ATP-binding region signature.
553482008041	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
553482008042	active site
553482008043	HMMPfam hit to PF00481, Protein phosphatase 2C, score 3.8e-07
553482008044	16S rRNA methyltransferase B; Provisional; Region: PRK14902
553482008045	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
553482008046	putative RNA binding site [nucleotide binding]; other site
553482008047	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
553482008048	HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 1.1e-42
553482008049	PS01153 NOL1/NOP2/sun family signature.
553482008050	HMMPfam hit to PF01029, NusB family, score 7.4e-30
553482008051	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
553482008052	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
553482008053	putative active site [active]
553482008054	substrate binding site [chemical binding]; other site
553482008055	putative cosubstrate binding site; other site
553482008056	catalytic site [active]
553482008057	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
553482008058	substrate binding site [chemical binding]; other site
553482008059	HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 2.3e-35
553482008060	HMMPfam hit to PF00551, Formyl transferase, score 1.4e-36
553482008061	primosome assembly protein PriA; Validated; Region: PRK05580
553482008062	primosome assembly protein PriA; Validated; Region: PRK05580
553482008063	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482008064	ATP binding site [chemical binding]; other site
553482008065	putative Mg++ binding site [ion binding]; other site
553482008066	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008067	nucleotide binding region [chemical binding]; other site
553482008068	ATP-binding site [chemical binding]; other site
553482008069	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.1e-07
553482008070	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 7.1e-25
553482008071	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.5e-29
553482008072	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008073	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
553482008074	HMMPfam hit to PF01192, RNA polymerase Rpb6, score 4e-14
553482008075	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
553482008076	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
553482008077	catalytic site [active]
553482008078	G-X2-G-X-G-K; other site
553482008079	HMMPfam hit to PF00625, Guanylate kinase, score 3.5e-46
553482008080	hypothetical protein; Provisional; Region: PRK00106
553482008081	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482008082	HMMPfam hit to PF01966, HD domain, score 8.3e-24
553482008083	HMMPfam hit to PF00013, KH domain, score 4.3e-10
553482008084	1 transmembrane helix predicted for SEQ1781 by TMHMM2.0 at aa 2-24
553482008085	S-Ribosylhomocysteinase (LuxS); Region: LuxS; cl00802
553482008086	HMMPfam hit to PF02664, S-Ribosylhomocysteinase (LuxS), score 1.2e-44
553482008087	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008088	Helix-turn-helix domains; Region: HTH; cl00088
553482008089	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008090	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008091	HMMPfam hit to PF02178, no description, score 0.21
553482008092	putative transposase OrfB; Reviewed; Region: PHA02517
553482008093	HTH-like domain; Region: HTH_21; pfam13276
553482008094	Integrase core domain; Region: rve; cl01316
553482008095	Integrase core domain; Region: rve_3; cl15866
553482008096	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482008097	1 transmembrane helix predicted for SEQ1785 by TMHMM2.0 at aa 168-190
553482008098	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
553482008099	THUMP domain; Region: THUMP; cl12076
553482008100	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482008101	HMMPfam hit to PF01170, RNA methylase family UPF0020, score 1.1e-64
553482008102	PS00092 N-6 Adenine-specific DNA methylases signature.
553482008103	cell division protein GpsB; Provisional; Region: PRK14127
553482008104	DivIVA domain; Region: DivI1A_domain; TIGR03544
553482008105	HMMPfam hit to PF05103, DivIVA protein, score 1e-27
553482008106	Protein of unknown function (DUF1273); Region: DUF1273; cl01859
553482008107	HMMPfam hit to PF06908, Protein of unknown function (DUF1273), score 6e-105
553482008108	Recombination protein U; Region: RecU; cl01314
553482008109	PS00030 Eukaryotic RNA-binding region RNP-1 signature.
553482008110	Transglycosylase; Region: Transgly; cl07896
553482008111	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
553482008112	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482008113	1 transmembrane helix predicted for SEQ1790 by TMHMM2.0 at aa 17-39
553482008114	HMMPfam hit to PF00912, Transglycosylase, score 7.5e-84
553482008115	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 8.3e-20
553482008116	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008117	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
553482008118	trimer interface [polypeptide binding]; other site
553482008119	active site
553482008120	G bulge; other site
553482008121	HMMPfam hit to PF03051, Peptidase C1-like family, score 7.2e-300
553482008122	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482008123	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008124	PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site.
553482008125	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
553482008126	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
553482008127	homodimer interface [polypeptide binding]; other site
553482008128	NAD binding pocket [chemical binding]; other site
553482008129	ATP binding pocket [chemical binding]; other site
553482008130	Mg binding site [ion binding]; other site
553482008131	active-site loop [active]
553482008132	HMMPfam hit to PF02540, NAD synthase, score 4.1e-100
553482008133	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
553482008134	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
553482008135	active site
553482008136	HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 3.7e-10
553482008137	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
553482008138	HMMPfam hit to PF00324, Amino acid permease, score 1.5e-86
553482008139	12 transmembrane helices predicted for SEQ1794 by TMHMM2.0 at aa 26-48, 53-72, 92-114, 129-151, 158-180, 210-232, 252-270, 290-312, 342-364, 374-396, 409-431 and 436-453
553482008140	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008141	PS00218 Amino acid permeases signature.
553482008142	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
553482008143	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482008144	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482008145	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 4.6e-41
553482008146	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 7.1e-25
553482008147	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
553482008148	Protein of unknown function (DUF4059); Region: DUF4059; pfam13268
553482008149	2 transmembrane helices predicted for SEQ1796 by TMHMM2.0 at aa 13-30 and 50-72
553482008150	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482008151	HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, repectively.  Histidine permease is a multisubunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP.  HisP...; Region: ABC_HisP_GlnQ_permeases; cd03262
553482008152	Walker A/P-loop; other site
553482008153	ATP binding site [chemical binding]; other site
553482008154	Q-loop/lid; other site
553482008155	ABC transporter signature motif; other site
553482008156	Walker B; other site
553482008157	D-loop; other site
553482008158	H-loop/switch region; other site
553482008159	HMMPfam hit to PF00005, ABC transporter, score 8.6e-69
553482008160	PS00211 ABC transporters family signature.
553482008161	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008162	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008163	dimer interface [polypeptide binding]; other site
553482008164	conserved gate region; other site
553482008165	putative PBP binding loops; other site
553482008166	ABC-ATPase subunit interface; other site
553482008167	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-17
553482008168	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482008169	Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 165-186, sequence TGEIEAAKSLGMTSAQVYRRVI
553482008170	3 transmembrane helices predicted for SEQ1798 by TMHMM2.0 at aa 57-79, 92-114 and 129-151
553482008171	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482008172	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482008173	substrate binding pocket [chemical binding]; other site
553482008174	membrane-bound complex binding site; other site
553482008175	hinge residues; other site
553482008176	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 5.4e-50
553482008177	1 transmembrane helix predicted for SEQ1799 by TMHMM2.0 at aa 7-29
553482008178	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
553482008179	DEAD-like helicases superfamily; Region: DEXDc; smart00487
553482008180	ATP binding site [chemical binding]; other site
553482008181	Mg++ binding site [ion binding]; other site
553482008182	motif III; other site
553482008183	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008184	nucleotide binding region [chemical binding]; other site
553482008185	ATP-binding site [chemical binding]; other site
553482008186	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 3.5e-26
553482008187	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.7e-53
553482008188	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
553482008189	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
553482008190	Mg++ binding site [ion binding]; other site
553482008191	putative catalytic motif [active]
553482008192	putative substrate binding site [chemical binding]; other site
553482008193	10 transmembrane helices predicted for SEQ1802 by TMHMM2.0 at aa 4-26, 47-69, 79-98, 119-138, 148-170, 177-196, 200-219, 226-248, 252-274 and 317-334
553482008194	HMMPfam hit to PF00953, Glycosyl transferase family, score 1.5e-59
553482008195	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
553482008196	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482008197	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482008198	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
553482008199	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
553482008200	HMMPfam hit to PF03793, PASTA domain, score 1.5e-10
553482008201	HMMPfam hit to PF03793, PASTA domain, score 6.9e-07
553482008202	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.2e-90
553482008203	HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 6e-46
553482008204	PS00430 TonB-dependent receptor proteins signature 1.
553482008205	1 transmembrane helix predicted for SEQ1803 by TMHMM2.0 at aa 26-48
553482008206	Septum formation initiator; Region: DivIC; cl11433
553482008207	HMMPfam hit to PF04977, Septum formation initiator, score 0.00019
553482008208	1 transmembrane helix predicted for SEQ1804 by TMHMM2.0 at aa 27-46
553482008209	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
553482008210	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482008211	HMMPfam hit to PF01795, MraW methylase family, score 8.9e-191
553482008212	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
553482008213	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
553482008214	putative catalytic cysteine [active]
553482008215	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
553482008216	nucleotide binding site [chemical binding]; other site
553482008217	homotetrameric interface [polypeptide binding]; other site
553482008218	putative phosphate binding site [ion binding]; other site
553482008219	putative allosteric binding site; other site
553482008220	HMMPfam hit to PF00696, Amino acid kinase family, score 4.5e-61
553482008221	1 transmembrane helix predicted for SEQ1810 by TMHMM2.0 at aa 10-25
553482008222	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008223	Helix-turn-helix domains; Region: HTH; cl00088
553482008224	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008225	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008226	HMMPfam hit to PF02178, no description, score 0.21
553482008227	putative transposase OrfB; Reviewed; Region: PHA02517
553482008228	HTH-like domain; Region: HTH_21; pfam13276
553482008229	Integrase core domain; Region: rve; cl01316
553482008230	Integrase core domain; Region: rve_3; cl15866
553482008231	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482008232	12 transmembrane helices predicted for SEQ1814 by TMHMM2.0 at aa 48-65, 75-97, 125-147, 152-174, 190-212, 248-267, 319-341, 356-378, 407-429, 433-455, 479-501 and 511-531
553482008233	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008234	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482008235	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482008236	This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity.  In bacteria and archaea, these transporters usually include an ATP-binding...; Region: ABC_DR_subfamily_A; cd03230
553482008237	Walker A/P-loop; other site
553482008238	ATP binding site [chemical binding]; other site
553482008239	Q-loop/lid; other site
553482008240	ABC transporter signature motif; other site
553482008241	Walker B; other site
553482008242	D-loop; other site
553482008243	H-loop/switch region; other site
553482008244	HMMPfam hit to PF00005, ABC transporter, score 5.6e-42
553482008245	PS00211 ABC transporters family signature.
553482008246	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008247	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482008248	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482008249	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482008250	1 transmembrane helix predicted for SEQ1817 by TMHMM2.0 at aa 9-31
553482008251	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 6.5e-11
553482008252	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.3e-14
553482008253	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.5e-15
553482008254	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.6e-14
553482008255	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 5e-12
553482008256	HMMPfam hit to PF00746, Gram positive anchor, score 6.2e-12
553482008257	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482008258	transketolase; Reviewed; Region: PRK05899
553482008259	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
553482008260	TPP-binding site [chemical binding]; other site
553482008261	dimer interface [polypeptide binding]; other site
553482008262	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
553482008263	PYR/PP interface [polypeptide binding]; other site
553482008264	dimer interface [polypeptide binding]; other site
553482008265	TPP binding site [chemical binding]; other site
553482008266	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482008267	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 0.00029
553482008268	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 9.9e-63
553482008269	PS00802 Transketolase signature 2.
553482008270	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 6.1e-202
553482008271	PS00801 Transketolase signature 1.
553482008272	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
553482008273	active site
553482008274	intersubunit interactions; other site
553482008275	catalytic residue [active]
553482008276	HMMPfam hit to PF00923, Transaldolase, score 7.1e-53
553482008277	PS01054 Transaldolase signature 1.
553482008278	glycerol kinase; Provisional; Region: glpK; PRK00047
553482008279	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
553482008280	N- and C-terminal domain interface [polypeptide binding]; other site
553482008281	active site
553482008282	MgATP binding site [chemical binding]; other site
553482008283	catalytic site [active]
553482008284	metal binding site [ion binding]; metal-binding site
553482008285	glycerol binding site [chemical binding]; other site
553482008286	homotetramer interface [polypeptide binding]; other site
553482008287	homodimer interface [polypeptide binding]; other site
553482008288	FBP binding site [chemical binding]; other site
553482008289	protein IIAGlc interface [polypeptide binding]; other site
553482008290	PS00014 Endoplasmic reticulum targeting sequence.
553482008291	HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 1.2e-76
553482008292	PS00445 FGGY family of carbohydrate kinases signature 2.
553482008293	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 3e-116
553482008294	PS00933 FGGY family of carbohydrate kinases signature 1.
553482008295	Peptidase propeptide and YPEB domain; Region: PepSY; cl15815
553482008296	Peptidase propeptide and YPEB domain; Region: PepSY; cl15815
553482008297	HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.0015
553482008298	HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.00039
553482008299	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008300	2 transmembrane helices predicted for SEQ1822 by TMHMM2.0 at aa 2-19 and 29-63
553482008301	gene remnant
553482008302	Predicted methyltransferases [General function prediction only]; Region: COG0313
553482008303	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 7.6e-40
553482008304	PS01296 Uncharacterized protein family UPF0011 signature.
553482008305	TSC-22/dip/bun family; Region: TSC22; cl01853
553482008306	HMMPfam hit to PF06156, Protein of unknown function (DUF972), score 3.9e-63
553482008307	PSP1 C-terminal conserved region; Region: PSP1; cl00770
553482008308	HMMPfam hit to PF04468, PSP1 C-terminal conserved region, score 2.7e-26
553482008309	DNA polymerase III subunit delta'; Validated; Region: PRK07276
553482008310	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482008311	thymidylate kinase; Validated; Region: tmk; PRK00698
553482008312	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
553482008313	TMP-binding site; other site
553482008314	ATP-binding site [chemical binding]; other site
553482008315	HMMPfam hit to PF02223, Thymidylate kinase, score 6.6e-67
553482008316	PS01331 Thymidylate kinase signature.
553482008317	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008318	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; cl11453
553482008319	Protein of unknown function (DUF964); Region: DUF964; cl01483
553482008320	HMMPfam hit to PF07050, Protein of unknown function (DUF1333), score 2.3e-25
553482008321	Clp protease; Region: CLP_protease; pfam00574
553482008322	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
553482008323	oligomer interface [polypeptide binding]; other site
553482008324	active site residues [active]
553482008325	HMMPfam hit to PF00574, Clp protease, score 5.3e-120
553482008326	PS00382 Endopeptidase Clp histidine active site.
553482008327	PS00381 Endopeptidase Clp serine active site.
553482008328	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482008329	active site
553482008330	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.3e-15
553482008331	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
553482008332	MatE; Region: MatE; cl10513
553482008333	12 transmembrane helices predicted for SEQ1834 by TMHMM2.0 at aa 21-43, 58-77, 98-117, 132-154, 194-216, 302-324, 336-358, 373-395, 407-426, 431-448, 468-490 and 500-522
553482008334	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 9.1e-10
553482008335	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022
553482008336	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482008337	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482008338	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482008339	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 0.0075
553482008340	HMMPfam hit to PF08245, Mur ligase middle domain, score 2.9e-34
553482008341	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 2.2e-19
553482008342	PS00030 Eukaryotic RNA-binding region RNP-1 signature.
553482008343	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
553482008344	ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea.  Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC...; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
553482008345	Walker A/P-loop; other site
553482008346	ATP binding site [chemical binding]; other site
553482008347	Q-loop/lid; other site
553482008348	ABC transporter signature motif; other site
553482008349	Walker B; other site
553482008350	D-loop; other site
553482008351	H-loop/switch region; other site
553482008352	HMMPfam hit to PF00005, ABC transporter, score 6.4e-49
553482008353	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008354	PS00211 ABC transporters family signature.
553482008355	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
553482008356	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
553482008357	putative ligand binding residues [chemical binding]; other site
553482008358	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008359	HMMPfam hit to PF01497, Periplasmic binding protein, score 9.6e-41
553482008360	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482008361	ABC-ATPase subunit  interface; other site
553482008362	dimer interface [polypeptide binding]; other site
553482008363	putative PBP binding regions; other site
553482008364	10 transmembrane helices predicted for SEQ1838 by TMHMM2.0 at aa 19-41, 68-90, 103-120, 125-147, 160-179, 184-201, 206-228, 243-274, 286-303 and 318-335
553482008365	HMMPfam hit to PF01032, FecCD transport family, score 3.5e-94
553482008366	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
553482008367	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482008368	ABC-ATPase subunit  interface; other site
553482008369	dimer interface [polypeptide binding]; other site
553482008370	putative PBP binding regions; other site
553482008371	9 transmembrane helices predicted for SEQ1839 by TMHMM2.0 at aa 7-29, 57-79, 92-109, 119-141, 148-170, 198-220, 241-263, 283-305 and 312-329
553482008372	HMMPfam hit to PF01032, FecCD transport family, score 1.8e-80
553482008373	PS00215 Mitochondrial energy transfer proteins signature.
553482008374	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
553482008375	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
553482008376	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
553482008377	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
553482008378	DHHA2 domain; Region: DHHA2; pfam02833
553482008379	HMMPfam hit to PF02833, DHHA2 domain, score 4e-53
553482008380	HMMPfam hit to PF01368, DHH family, score 6e-16
553482008381	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
553482008382	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482008383	FeS/SAM binding site; other site
553482008384	PS01087 Radical activating enzymes signature.
553482008385	PS00190 Cytochrome c family heme-binding site signature.
553482008386	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
553482008387	Domain of unknown function DUF21; Region: DUF21; pfam01595
553482008388	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
553482008389	Transporter associated domain; Region: CorC_HlyC; cl08393
553482008390	HMMPfam hit to PF03471, Transporter associated domain, score 6.8e-23
553482008391	HMMPfam hit to PF00571, CBS domain pair, score 4e-24
553482008392	HMMPfam hit to PF01595, Domain of unknown function DUF21, score 2.2e-73
553482008393	4 transmembrane helices predicted for SEQ1844 by TMHMM2.0 at aa 10-29, 71-93, 103-125 and 137-159
553482008394	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482008395	HMMPfam hit to PF06962, rRNA methylase, score 9.1e-81
553482008396	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase; Region: APH; cd05150
553482008397	active site
553482008398	ATP binding site [chemical binding]; other site
553482008399	Phosphotransferase enzyme family; Region: APH; pfam01636
553482008400	antibiotic binding site [chemical binding]; other site
553482008401	HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 2.1e-18
553482008402	PS00109 Tyrosine protein kinases specific active-site signature.
553482008403	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
553482008404	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
553482008405	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
553482008406	active site
553482008407	6 transmembrane helices predicted for SEQ1848 by TMHMM2.0 at aa 7-29, 58-80, 87-109, 124-146, 153-175 and 185-202
553482008408	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl01942
553482008409	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
553482008410	5 transmembrane helices predicted for SEQ1849 by TMHMM2.0 at aa 15-37, 44-66, 86-105, 117-139 and 159-181
553482008411	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482008412	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is 'interfacial activation', the process of becoming...; Region: Lipase; cl14883
553482008413	nucleophilic elbow; other site
553482008414	catalytic triad; other site
553482008415	PS00120 Lipases, serine active site.
553482008416	1 transmembrane helix predicted for SEQ1853 by TMHMM2.0 at aa 12-31
553482008417	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae serotype III hypothetical protein GBS1967 UniProt:Q8E2Z6 (EMBL:AL766855 (402 aa) fasta scores: E()=0.024, 35.366% id in 82 aa. Similar to the N-terminal region of SEQ1052, 52.000% identity (53.425% ungapped) in 75 aa overlap (5-79:3-75)
553482008418	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae CJB111 uncharacterized protein UniProt:Q3DDH3 (EMBL:AAJQ01000032) (71 aa) fasta scores: E()=0.61, 38.182% id in 55 aa
553482008419	1 transmembrane helix predicted for SEQ1857 by TMHMM2.0 at aa 15-34
553482008420	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
553482008421	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 5.2e-42
553482008422	Haemolytic domain; Region: Haemolytic; cl00506
553482008423	HMMPfam hit to PF01809, Domain of unknown function DUF37, score 8.6e-35
553482008424	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482008425	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482008426	RNA binding surface [nucleotide binding]; other site
553482008427	Pseudouridine synthases  are responsible for the synthesis of pseudouridine from uracil in ribosomal RNA. The RsuA subfamily includes Pseudouridine Synthase similar to Ribosomal small subunit pseudouridine 516 synthase. Most of the proteins in this...; Region: PseudoU_synth_RsuA_like; cd02870
553482008428	active site
553482008429	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.1e-23
553482008430	PS01149 Rsu family of pseudouridine synthase signature.
553482008431	HMMPfam hit to PF01479, S4 domain, score 3.5e-15
553482008432	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
553482008433	HMMPfam hit to PF04079, transcriptional regulators (Ypuh-li, score 3.1e-75
553482008434	Predicted helix-turn-helix motif with score 1232.000, SD 3.38 at aa 19-40, sequence LSLRQLASLLELTPTALQQQLD
553482008435	ScpA/B protein; Region: ScpA_ScpB; cl00598
553482008436	HMMPfam hit to PF02616, ScpA/B protein, score 1.1e-22
553482008437	site-specific tyrosine recombinase XerD-like protein; Reviewed; Region: xerD; PRK02436
553482008438	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
553482008439	DNA binding site [nucleotide binding]
553482008440	Int/Topo IB signature motif; other site
553482008441	active site
553482008442	catalytic residues [active]
553482008443	HMMPfam hit to PF00589, Phage integrase family, score 0.02
553482008444	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
553482008445	HMMPfam hit to PF00571, CBS domain pair, score 3.7e-21
553482008446	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
553482008447	active site
553482008448	metal binding site [ion binding]; metal-binding site
553482008449	homotetramer interface [polypeptide binding]; other site
553482008450	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008451	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 0.00011
553482008452	putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Reviewed; Region: PRK02491
553482008453	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
553482008454	active site
553482008455	dimerization interface [polypeptide binding]; other site
553482008456	HMMPfam hit to PF01725, Ham1 family, score 3.5e-66
553482008457	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008458	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
553482008459	HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 1.5e-100
553482008460	PS00924 Aspartate and glutamate racemases signature 2.
553482008461	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008462	Uncharacterized protein family (UPF0154); Region: UPF0154; cl01536
553482008463	HMMPfam hit to PF03672, Uncharacterised protein family (UPF0154), score 5.1e-19
553482008464	1 transmembrane helix predicted for SEQ1869 by TMHMM2.0 at aa 4-26
553482008465	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
553482008466	HMMPfam hit to PF01027, Uncharacterised protein family UPF0005, score 4e-21
553482008467	7 transmembrane helices predicted for SEQ1870 by TMHMM2.0 at aa 21-43, 58-76, 83-105, 110-129, 142-159, 163-182 and 202-224
553482008468	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482008469	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
553482008470	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
553482008471	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
553482008472	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 3e-49
553482008473	HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 1.6e-15
553482008474	putative transposase OrfB; Reviewed; Region: PHA02517
553482008475	HTH-like domain; Region: HTH_21; pfam13276
553482008476	Integrase core domain; Region: rve; cl01316
553482008477	Integrase core domain; Region: rve_3; cl15866
553482008478	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482008479	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008480	Helix-turn-helix domains; Region: HTH; cl00088
553482008481	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008482	HMMPfam hit to PF02178, no description, score 0.21
553482008483	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008484	Acylphosphatase; Region: Acylphosphatase; cl00551
553482008485	HMMPfam hit to PF00708, Acylphosphatase, score 2.5e-07
553482008486	PS00150 Acylphosphatase signature 1.
553482008487	OxaA-like protein precursor; Provisional; Region: PRK02463
553482008488	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
553482008489	5 transmembrane helices predicted for SEQ1878 by TMHMM2.0 at aa 7-26, 58-80, 135-157, 177-199 and 220-242
553482008490	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008491	HMMPfam hit to PF02096, 60Kd inner membrane protein, score 1.1e-36
553482008492	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008493	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
553482008494	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
553482008495	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
553482008496	HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 2.2e-16
553482008497	PS00830 Prokaryotic transcription elongation factors signature 2.
553482008498	HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 3e-24
553482008499	YceG-like family; Region: YceG; pfam02618
553482008500	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
553482008501	dimerization interface [polypeptide binding]; other site
553482008502	HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 8.4e-138
553482008503	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008504	1 transmembrane helix predicted for SEQ1880 by TMHMM2.0 at aa 157-179
553482008505	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
553482008506	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482008507	Coenzyme A binding pocket [chemical binding]; other site
553482008508	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.7e-10
553482008509	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
553482008510	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482008511	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482008512	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482008513	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 9.7e-20
553482008514	HMMPfam hit to PF08245, Mur ligase middle domain, score 5.8e-27
553482008515	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 3.5e-37
553482008516	SWIM zinc finger; Region: SWIM; cl15408
553482008517	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
553482008518	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482008519	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482008520	ATP binding site [chemical binding]; other site
553482008521	putative Mg++ binding site [ion binding]; other site
553482008522	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008523	nucleotide binding region [chemical binding]; other site
553482008524	ATP-binding site [chemical binding]; other site
553482008525	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.3e-25
553482008526	PS00697 ATP-dependent DNA ligase AMP-binding site.
553482008527	HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 3.2e-60
553482008528	HMMPfam hit to PF08455, Bacterial SNF2 helicase associated, score 4.5e-128
553482008529	HMMPfam hit to PF04434, SWIM zinc finger, score 4.5e-07
553482008530	GTP-binding protein Der; Reviewed; Region: PRK00093
553482008531	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
553482008532	G1 box; other site
553482008533	GTP/Mg2+ binding site [chemical binding]; other site
553482008534	Switch I region; other site
553482008535	G2 box; other site
553482008536	Switch II region; other site
553482008537	G3 box; other site
553482008538	G4 box; other site
553482008539	G5 box; other site
553482008540	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
553482008541	G1 box; other site
553482008542	GTP/Mg2+ binding site [chemical binding]; other site
553482008543	Switch I region; other site
553482008544	G2 box; other site
553482008545	G3 box; other site
553482008546	Switch II region; other site
553482008547	G4 box; other site
553482008548	G5 box; other site
553482008549	HMMPfam hit to PF01926, GTPase of unknown function, score 4.1e-41
553482008550	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008551	HMMPfam hit to PF01926, GTPase of unknown function, score 8.5e-46
553482008552	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008553	primosomal protein DnaI; Reviewed; Region: PRK08939
553482008554	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
553482008555	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482008556	Walker A motif; other site
553482008557	ATP binding site [chemical binding]; other site
553482008558	Walker B motif; other site
553482008559	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008560	HMMPfam hit to PF07319, Primosomal protein DnaI N-terminus, score 2.7e-45
553482008561	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
553482008562	HMMPfam hit to PF07261, Replication initiation and membrane attachme, score 6.7e-07
553482008563	Predicted helix-turn-helix motif with score 979.000, SD 2.52 at aa 359-380, sequence TSQEEQAKLEQFKQAALKRLEN
553482008564	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
553482008565	ATP cone domain; Region: ATP-cone; pfam03477
553482008566	HMMPfam hit to PF03477, ATP cone domain, score 2.2e-33
553482008567	PS00190 Cytochrome c family heme-binding site signature.
553482008568	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
553482008569	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
553482008570	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482008571	dimer interface [polypeptide binding]; other site
553482008572	phosphorylation site [posttranslational modification]
553482008573	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482008574	ATP binding site [chemical binding]; other site
553482008575	Mg2+ binding site [ion binding]; other site
553482008576	G-X-G motif; other site
553482008577	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.8e-31
553482008578	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.8e-17
553482008579	HMMPfam hit to PF00672, HAMP domain, score 1.1e-10
553482008580	2 transmembrane helices predicted for SEQ1889 by TMHMM2.0 at aa 20-42 and 187-209
553482008581	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482008582	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482008583	active site
553482008584	phosphorylation site [posttranslational modification]
553482008585	intermolecular recognition site; other site
553482008586	dimerization interface [polypeptide binding]; other site
553482008587	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482008588	DNA binding site [nucleotide binding]
553482008589	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.6e-19
553482008590	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.6e-40
553482008591	PS00217 Sugar transport proteins signature 2.
553482008592	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
553482008593	HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 5.4e-43
553482008594	Peptidase family M48; Region: Peptidase_M48; cl12018
553482008595	HMMPfam hit to PF01435, Peptidase family M48, score 5.7e-20
553482008596	4 transmembrane helices predicted for SEQ1892 by TMHMM2.0 at aa 13-35, 45-67, 157-179 and 194-216
553482008597	LemA family; Region: LemA; cl00742
553482008598	HMMPfam hit to PF04011, LemA family, score 6.5e-108
553482008599	1 transmembrane helix predicted for SEQ1893 by TMHMM2.0 at aa 4-26
553482008600	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008601	S-adenosylmethionine binding site [chemical binding]; other site
553482008602	HMMPfam hit to PF02527, Glucose inhibited division protein, score 9.4e-58
553482008603	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
553482008604	Cation transport protein; Region: TrkH; cl10514
553482008605	9 transmembrane helices predicted for SEQ1895 by TMHMM2.0 at aa 15-37, 49-67, 77-99, 128-150, 160-182, 195-217, 242-261, 365-384 and 419-441
553482008606	HMMPfam hit to PF02386, Cation transport protein, score 3.9e-59
553482008607	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
553482008608	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482008609	HMMPfam hit to PF02254, TrkA-N domain, score 9.2e-38
553482008610	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
553482008611	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 2.9e-112
553482008612	9 transmembrane helices predicted for SEQ1897 by TMHMM2.0 at aa 17-39, 43-65, 78-100, 136-158, 178-200, 210-232, 287-309, 324-346 and 353-375
553482008613	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008614	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
553482008615	HMMPfam hit to PF05525, Branched-chain amino acid transport p, score 4.7e-206
553482008616	12 transmembrane helices predicted for SEQ1898 by TMHMM2.0 at aa 7-29, 39-61, 78-97, 117-136, 148-170, 192-214, 234-256, 296-318, 331-353, 357-376, 385-407 and 427-449
553482008617	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008618	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
553482008619	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6e-13
553482008620	4 transmembrane helices predicted for SEQ1899 by TMHMM2.0 at aa 32-54, 75-97, 166-188 and 201-220
553482008621	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
553482008622	MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport.  Other members of this system include the MetP permease and  the MetQ substrate binding protein.  ABC...; Region: ABC_MetN_methionine_transporter; cd03258
553482008623	Walker A/P-loop; other site
553482008624	ATP binding site [chemical binding]; other site
553482008625	Q-loop/lid; other site
553482008626	ABC transporter signature motif; other site
553482008627	Walker B; other site
553482008628	D-loop; other site
553482008629	H-loop/switch region; other site
553482008630	NIL domain; Region: NIL; cl09633
553482008631	HMMPfam hit to PF00005, ABC transporter, score 2.3e-67
553482008632	PS00211 ABC transporters family signature.
553482008633	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008634	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
553482008635	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_4; cd05681
553482008636	metal binding site [ion binding]; metal-binding site
553482008637	dimer interface [polypeptide binding]; other site
553482008638	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 7.2e-27
553482008639	Predicted helix-turn-helix motif with score 1057.000, SD 2.79 at aa 363-384, sequence YTLGEMSYRSDLSSSAISQLIA
553482008640	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.2e-08
553482008641	NMT1-like family; Region: NMT1_2; cl15260
553482008642	HMMPfam hit to PF03180, NLPA lipoprotein, score 2.5e-112
553482008643	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008644	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482008645	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482008646	substrate binding pocket [chemical binding]; other site
553482008647	membrane-bound complex binding site; other site
553482008648	hinge residues; other site
553482008649	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.2e-75
553482008650	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008651	Transcriptional regulator; Region: Transcrip_reg; cl00361
553482008652	HMMPfam hit to PF01709, Domain of unknown function DUF28, score 4.2e-125
553482008653	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
553482008654	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
553482008655	DNA binding residues [nucleotide binding]
553482008656	dimer interface [polypeptide binding]; other site
553482008657	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
553482008658	HMMPfam hit to PF07739, TipAS antibiotic-recognition domain, score 4.6e-35
553482008659	HMMPfam hit to PF00376, MerR family regulatory protein, score 5e-06
553482008660	hypothetical protein; Provisional; Region: PRK13670
553482008661	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482008662	HMMPfam hit to PF05636, Protein of unknown function (DUF795), score 4.6e-178
553482008663	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
553482008664	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008665	S-adenosylmethionine binding site [chemical binding]; other site
553482008666	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 1.2e-05
553482008667	HMMPfam hit to PF08241, Methyltransferase domain, score 2.3e-21
553482008668	HMMPfam hit to PF08242, Methyltransferase domain, score 4.6e-18
553482008669	Oligomerisation domain; Region: Oligomerisation; cl00519
553482008670	HMMPfam hit to PF02410, Domain of unknown function DUF143, score 1.4e-43
553482008671	Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism]; Region: COG1713
553482008672	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482008673	HMMPfam hit to PF01966, HD domain, score 2.5e-11
553482008674	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
553482008675	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
553482008676	active site
553482008677	(T/H)XGH motif; other site
553482008678	HMMPfam hit to PF01467, Cytidylyltransferase, score 3.9e-61
553482008679	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
553482008680	HMMPfam hit to PF01985, CRS1 / YhbY domain, score 4.6e-34
553482008681	GTPase YqeH; Provisional; Region: PRK13796
553482008682	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
553482008683	GTP/Mg2+ binding site [chemical binding]; other site
553482008684	G4 box; other site
553482008685	G5 box; other site
553482008686	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482008687	G1 box; other site
553482008688	G1 box; other site
553482008689	GTP/Mg2+ binding site [chemical binding]; other site
553482008690	G2 box; other site
553482008691	Switch I region; other site
553482008692	G2 box; other site
553482008693	Switch I region; other site
553482008694	G3 box; other site
553482008695	G3 box; other site
553482008696	Switch II region; other site
553482008697	Switch II region; other site
553482008698	G4 box; other site
553482008699	HMMPfam hit to PF01926, GTPase of unknown function, score 7.6e-11
553482008700	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008701	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
553482008702	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482008703	active site
553482008704	motif I; other site
553482008705	motif II; other site
553482008706	PS00678 Trp-Asp (WD) repeats signature.
553482008707	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
553482008708	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482008709	Walker A/P-loop; other site
553482008710	ATP binding site [chemical binding]; other site
553482008711	Q-loop/lid; other site
553482008712	ABC transporter signature motif; other site
553482008713	Walker B; other site
553482008714	D-loop; other site
553482008715	H-loop/switch region; other site
553482008716	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482008717	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 1.6e-07
553482008718	HMMPfam hit to PF00005, ABC transporter, score 7.4e-53
553482008719	PS00211 ABC transporters family signature.
553482008720	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008721	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
553482008722	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
553482008723	Walker A/P-loop; other site
553482008724	ATP binding site [chemical binding]; other site
553482008725	Q-loop/lid; other site
553482008726	ABC transporter signature motif; other site
553482008727	Walker B; other site
553482008728	D-loop; other site
553482008729	H-loop/switch region; other site
553482008730	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482008731	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 8.5e-23
553482008732	HMMPfam hit to PF00005, ABC transporter, score 5e-69
553482008733	PS00211 ABC transporters family signature.
553482008734	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008735	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
553482008736	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
553482008737	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.6e-37
553482008738	6 transmembrane helices predicted for SEQ1917 by TMHMM2.0 at aa 42-64, 110-132, 145-167, 171-193, 214-236 and 274-296
553482008739	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008740	dimer interface [polypeptide binding]; other site
553482008741	conserved gate region; other site
553482008742	putative PBP binding loops; other site
553482008743	ABC-ATPase subunit interface; other site
553482008744	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.5e-52
553482008745	6 transmembrane helices predicted for SEQ1918 by TMHMM2.0 at aa 9-31, 287-309, 321-343, 358-380, 419-441 and 461-483
553482008746	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
553482008747	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
553482008748	peptide binding site [polypeptide binding]; other site
553482008749	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2e-48
553482008750	PS01040 Bacterial extracellular solute-binding proteins, family 5 signature.
553482008751	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008752	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
553482008753	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482008754	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
553482008755	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008756	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 2.1e-106
553482008757	PS00307 Legume lectins beta-chain signature.
553482008758	HMMPfam hit to PF07943, Penicillin-binding protein 5, C-termina, score 1.9e-09
553482008759	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
553482008760	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
553482008761	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 1.3e-96
553482008762	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
553482008763	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
553482008764	2 transmembrane helices predicted for SEQ1922 by TMHMM2.0 at aa 5-23 and 368-390
553482008765	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 6e-37
553482008766	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008767	Helix-turn-helix domains; Region: HTH; cl00088
553482008768	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008769	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008770	HMMPfam hit to PF02178, no description, score 0.21
553482008772	Uncharacterized protein family (UPF0051); Region: UPF0051; cl03223
553482008773	FeS assembly protein SufB; Region: sufB; TIGR01980
553482008774	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 8.1e-116
553482008775	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
553482008776	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
553482008777	trimerization site [polypeptide binding]; other site
553482008778	active site
553482008779	HMMPfam hit to PF01592, NifU-like N terminal domain, score 3.4e-28
553482008780	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
553482008781	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
553482008782	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482008783	catalytic residue [active]
553482008784	HMMPfam hit to PF00266, Aminotransferase class-V, score 6.2e-216
553482008785	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012
553482008786	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482008787	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
553482008788	Uncharacterized protein family (UPF0051); Region: UPF0051; cl03223
553482008789	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 4.4e-49
553482008790	FeS assembly ATPase SufC; Region: sufC; TIGR01978
553482008791	ABC-type transport system involved in Fe-S cluster assembly, ATPase component.  Biosynthesis of iron-sulfur clusters (Fe-S) depends on multiprotein systems.  The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under...; Region: ABC_FeS_Assembly; cd03217
553482008792	Walker A/P-loop; other site
553482008793	ATP binding site [chemical binding]; other site
553482008794	Q-loop/lid; other site
553482008795	ABC transporter signature motif; other site
553482008796	Walker B; other site
553482008797	D-loop; other site
553482008798	H-loop/switch region; other site
553482008799	HMMPfam hit to PF00005, ABC transporter, score 5.5e-31
553482008800	PS00211 ABC transporters family signature.
553482008801	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008802	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
553482008803	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
553482008804	Mg++ binding site [ion binding]; other site
553482008805	putative catalytic motif [active]
553482008806	substrate binding site [chemical binding]; other site
553482008807	11 transmembrane helices predicted for SEQ1931 by TMHMM2.0 at aa 10-31, 52-71, 81-103, 110-129, 144-163, 175-197, 201-218, 225-244, 254-276, 306-328 and 333-355
553482008808	HMMPfam hit to PF00953, Glycosyl transferase family, score 6e-41
553482008809	Negative regulator of genetic competence (MecA); Region: MecA; cl02022
553482008810	HMMPfam hit to PF05389, Negative regulator of genetic competence (Me, score 1.2e-113
553482008811	Predicted helix-turn-helix motif with score 1036.000, SD 2.72 at aa 84-105, sequence LNFEDLADLGDISQMTPEDFFR
553482008812	Bacitracin resistance protein BacA; Region: BacA; cl00858
553482008813	8 transmembrane helices predicted for SEQ1933 by TMHMM2.0 at aa 2-24, 44-66, 87-105, 115-133, 154-176, 186-208, 221-243 and 258-275
553482008814	HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 2.9e-119
553482008815	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482008816	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482008817	substrate binding pocket [chemical binding]; other site
553482008818	membrane-bound complex binding site; other site
553482008819	hinge residues; other site
553482008820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008821	dimer interface [polypeptide binding]; other site
553482008822	conserved gate region; other site
553482008823	putative PBP binding loops; other site
553482008824	ABC-ATPase subunit interface; other site
553482008825	4 transmembrane helices predicted for SEQ1934 by TMHMM2.0 at aa 5-24, 298-320, 360-382 and 473-495
553482008826	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 1.1e-35
553482008827	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-23
553482008828	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482008829	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482008830	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482008831	Walker A/P-loop; other site
553482008832	ATP binding site [chemical binding]; other site
553482008833	Q-loop/lid; other site
553482008834	ABC transporter signature motif; other site
553482008835	Walker B; other site
553482008836	D-loop; other site
553482008837	H-loop/switch region; other site
553482008838	HMMPfam hit to PF00005, ABC transporter, score 2.2e-62
553482008839	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008840	PS00211 ABC transporters family signature.
553482008841	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
553482008842	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_4; cd03407
553482008843	HMMPfam hit to PF01145, SPFH domain / Band, score 4.3e-41
553482008844	1 transmembrane helix predicted for SEQ1937 by TMHMM2.0 at aa 4-26
553482008845	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
553482008846	DAK2 domain; Region: Dak2; cl03685
553482008847	Uncharacterized protein, DegV family COG1307; Region: DegV; cl00577
553482008848	HMMPfam hit to PF02734, DAK2 domain, score 1.1e-75
553482008849	Asp23 family; Region: Asp23; cl00574
553482008850	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 1.9e-53
553482008851	Ribosomal L28 family; Region: Ribosomal_L28; cl00367
553482008852	HMMPfam hit to PF00830, Ribosomal L28 family, score 3.1e-24
553482008853	1 transmembrane helix predicted for SEQ1941 by TMHMM2.0 at aa 15-34
553482008854	PS00099 Thiolases active site.
553482008855	gene remnant. Similar to an internal region of Streptococcus thermophilus integrase Int UniProt:Q9L4G5 (EMBL:AJ243106 (448 aa) fasta scores: E()=0.032, 36.957% id in 46 aa
553482008856	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
553482008857	hypothetical protein; Provisional; Region: PRK08185
553482008858	intersubunit interface [polypeptide binding]; other site
553482008859	active site
553482008860	zinc binding site [ion binding]; other site
553482008861	Na+ binding site [ion binding]; other site
553482008862	PS00806 Fructose-bisphosphate aldolase class-II signature 2.
553482008863	PS00602 Fructose-bisphosphate aldolase class-II signature 1.
553482008864	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482008865	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
553482008866	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
553482008867	1 transmembrane helix predicted for SEQ1944 by TMHMM2.0 at aa 9-31
553482008868	CTP synthetase; Validated; Region: pyrG; PRK05380
553482008869	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
553482008870	Catalytic site [active]
553482008871	active site
553482008872	UTP binding site [chemical binding]; other site
553482008873	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
553482008874	active site
553482008875	putative oxyanion hole; other site
553482008876	catalytic triad [active]
553482008877	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 9.1e-69
553482008878	HMMPfam hit to PF06418, CTP synthase N-terminus, score 6.4e-216
553482008879	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; cl01319
553482008880	HMMPfam hit to PF05066, DNA-directed RNA polymerase delta subun, score 1.6e-98
553482008881	trigger factor; Provisional; Region: tig; PRK01490
553482008882	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl11587
553482008883	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
553482008884	HMMPfam hit to PF05698, Bacterial trigger factor protein (TF) C-ter, score 1.1e-67
553482008885	Predicted helix-turn-helix motif with score 987.000, SD 2.55 at aa 382-403, sequence KEINDLAAEYSMPVEQVRSLLS
553482008886	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomera, score 1.5e-27
553482008887	HMMPfam hit to PF05697, Bacterial trigger factor protein (TF), score 5.1e-58
553482008888	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac1_AmyA; cd11315
553482008889	active site
553482008890	Ca binding site [ion binding]; other site
553482008891	catalytic site [active]
553482008892	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
553482008893	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.3e-48
553482008894	Mechanosensitive ion channel; Region: MS_channel; pfam00924
553482008895	3 transmembrane helices predicted for SEQ1950 by TMHMM2.0 at aa 15-37, 72-94 and 104-126
553482008896	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 2.9e-53
553482008897	Protein of unknown function (DUF436); Region: DUF436; cl01860
553482008898	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl01942
553482008899	4 transmembrane helices predicted for SEQ1952 by TMHMM2.0 at aa 7-26, 53-75, 95-117 and 130-147
553482008900	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
553482008901	dimer interface [polypeptide binding]; other site
553482008902	substrate binding site [chemical binding]; other site
553482008903	ATP binding site [chemical binding]; other site
553482008904	HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 5.4e-66
553482008905	HMMPfam hit to PF01256, Carbohydrate kinase, score 0.00022
553482008906	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
553482008907	PseudoU_synth_EcTruA: Pseudouridine synthase, Escherichia coli TruA like. This group consists of eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA, Pseudomonas aeruginosa truA and human pseudouridine synthase-like 1 (PUSL1); Region: PseudoU_synth_EcTruA; cd02570
553482008908	dimerization interface 3.5A [polypeptide binding]; other site
553482008909	active site
553482008910	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.8e-31
553482008911	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 5.2e-38
553482008912	aspartate kinase; Reviewed; Region: PRK09034
553482008913	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
553482008914	putative catalytic residues [active]
553482008915	putative nucleotide binding site [chemical binding]; other site
553482008916	putative aspartate binding site [chemical binding]; other site
553482008917	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
553482008918	allosteric regulatory residue; other site
553482008919	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
553482008920	HMMPfam hit to PF00696, Amino acid kinase family, score 3.3e-33
553482008921	PS00324 Aspartokinase signature.
553482008922	HMMPfam hit to PF01842, ACT domain, score 0.75
553482008923	HMMPfam hit to PF01842, ACT domain, score 2.4e-08
553482008924	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482008925	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482008926	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482008927	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482008928	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482008929	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.034
553482008930	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.0072
553482008931	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 6.3e-10
553482008932	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 7.2e-35
553482008933	1 transmembrane helix predicted for SEQ1957 by TMHMM2.0 at aa 5-27
553482008934	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482008935	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
553482008936	intersubunit interface [polypeptide binding]; other site
553482008937	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 4.9e-115
553482008938	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482008939	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008940	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl01383
553482008941	1 transmembrane helix predicted for SEQ1959 by TMHMM2.0 at aa 487-509
553482008942	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008943	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008944	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
553482008945	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255
553482008946	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 1.8e-34
553482008947	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
553482008948	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482008949	DNA binding site [nucleotide binding]
553482008950	domain linker motif; other site
553482008951	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
553482008952	putative dimerization interface [polypeptide binding]; other site
553482008953	putative ligand binding site [chemical binding]; other site
553482008954	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI family, score 3.7e-10
553482008955	Predicted helix-turn-helix motif with score 2116.000, SD 6.39 at aa 2-23, sequence VTLKDIAALAKVSPATVSRVLN
553482008956	PS00356 Bacterial regulatory proteins, lacI family signature.
553482008957	galactokinase; Provisional; Region: PRK05322
553482008958	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
553482008959	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482008960	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
553482008961	PS00106 Galactokinase signature.
553482008962	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.4e-19
553482008963	PS00627 GHMP kinases ATP-binding domain.
553482008964	PS00012 Phosphopantetheine attachment site.
553482008965	HMMPfam hit to PF08544, GHMP kinases C terminal, score 6.7e-15
553482008966	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
553482008967	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
553482008968	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
553482008969	HMMPfam hit to PF01087, Galactose-1-phosphate uridyl transfer, score 7.5e-89
553482008970	HMMPfam hit to PF02744, Galactose-1-phosphate uridyl transfer, score 6.4e-89
553482008971	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
553482008972	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
553482008973	NAD binding site [chemical binding]; other site
553482008974	homodimer interface [polypeptide binding]; other site
553482008975	active site
553482008976	substrate binding site [chemical binding]; other site
553482008977	HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00068
553482008978	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 2.5e-76
553482008979	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 4.6e-05
553482008980	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 8.8e-09
553482008981	HMMPfam hit to PF07993, Male sterility protein, score 0.00044
553482008982	Galactose mutarotase and related enzymes [Carbohydrate transport and metabolism]; Region: GalM; COG2017
553482008983	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
553482008984	active site
553482008985	catalytic residues [active]
553482008986	HMMPfam hit to PF01263, Aldose 1-epimerase, score 3e-79
553482008987	PS00545 Aldose 1-epimerase active site.
553482008988	gene remnant. CDS contains at least two frameshifts. Similar to an internal region of Streptococcus pneumoniae transposase, IS200 family UniProt:Q97CV4 (EMBL:AE005672 (157 aa) fasta scores: E()=3.6e-16, 58.750% id in 80 aa
553482008989	gene remnant. CDS contains several frameshift and nonsense mutations. Similar to the C-terminal region of Streptococcus suis transposase UniProt:Q2ZZ41 (EMBL:AAFA02000065 (430 aa) fasta scores: E()=1.3e-25, 50.000% id in 192 aa
553482008990	genomic island
553482008991	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl11422
553482008992	HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 9.7e-13
553482008993	RelB antitoxin; Region: RelB; cl01171
553482008994	HMMPfam hit to PF04221, RelB antitoxin, score 0.011
553482008995	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
553482008996	Divergent AAA domain; Region: AAA_4; pfam04326
553482008997	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
553482008998	HMMPfam hit to PF04326, Divergent AAA domain, score 3.2e-10
553482008999	PS00215 Mitochondrial energy transfer proteins signature.
553482009000	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
553482009001	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
553482009002	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482009003	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482009004	ATP binding site [chemical binding]; other site
553482009005	putative Mg++ binding site [ion binding]; other site
553482009006	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
553482009007	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009008	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 6e-49
553482009009	HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 2.7e-51
553482009010	AAA domain; Region: AAA_13; pfam13166
553482009011	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009012	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009013	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009014	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
553482009015	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009016	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.8e-17
553482009017	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.9e-18
553482009018	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 8e-10
553482009019	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
553482009020	HsdM N-terminal domain; Region: HsdM_N; pfam12161
553482009021	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482009022	HMMPfam hit to PF02384, N-6 DNA Methylase, score 1.1e-169
553482009023	PS00092 N-6 Adenine-specific DNA methylases signature.
553482009024	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
553482009025	Predicted helix-turn-helix motif with score 1500.000, SD 4.30 at aa 45-66, sequence VRMAALSRWLDVSTTTLQKWTR
553482009026	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009027	non-specific DNA binding site [nucleotide binding]; other site
553482009028	salt bridge; other site
553482009029	sequence-specific DNA binding site [nucleotide binding]; other site
553482009030	Temperature dependent protein affecting M2 dsRNA replication; Region: MKT1_N; pfam12247
553482009031	HMMPfam hit to PF01381, Helix-turn-helix, score 3.7e-10
553482009032	Predicted helix-turn-helix motif with score 1361.000, SD 3.82 at aa 14-35, sequence KKIKSISEALDISYPTLSSYNQ
553482009033	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
553482009034	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
553482009035	Int/Topo IB signature motif; other site
553482009036	HMMPfam hit to PF00589, Phage integrase family, score 1.3e-19
553482009037	Ribosomal protein S9/S16; Region: Ribosomal_S9; cl00334
553482009038	HMMPfam hit to PF00380, Ribosomal protein S9/S16, score 6.5e-59
553482009039	PS00360 Ribosomal protein S9 signature.
553482009040	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
553482009041	23S rRNA interface [nucleotide binding]; other site
553482009042	L3 interface [polypeptide binding]; other site
553482009043	HMMPfam hit to PF00572, Ribosomal protein L13, score 2.8e-68
553482009044	PS00783 Ribosomal protein L13 signature.
553482009045	Uncharacterized protein, DegV family COG1307; Region: DegV; cl00577
553482009046	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 5.3e-72
553482009047	YacP-like NYN domain; Region: NYN_YacP; cl01491
553482009048	HMMPfam hit to PF05991, Protein of unknown function (DUF901), score 1.1e-82
553482009049	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
553482009050	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
553482009051	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
553482009052	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 9e-62
553482009053	HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 1.8e-12
553482009054	2 transmembrane helices predicted for SEQ1990 by TMHMM2.0 at aa 7-29 and 237-259
553482009055	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
553482009056	active site
553482009057	metal binding site [ion binding]; metal-binding site
553482009058	dimerization interface [polypeptide binding]; other site
553482009059	1 transmembrane helix predicted for SEQ1991 by TMHMM2.0 at aa 5-27
553482009060	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
553482009061	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
553482009062	active site
553482009063	HIGH motif; other site
553482009064	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
553482009065	KMSKS motif; other site
553482009066	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
553482009067	tRNA binding surface [nucleotide binding]; other site
553482009068	anticodon binding site; other site
553482009069	HMMPfam hit to PF01406, tRNA synthetases class I (C) catalytic d, score 1.6e-185
553482009070	serine O-acetyltransferase; Region: cysE; TIGR01172
553482009071	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
553482009072	trimer interface [polypeptide binding]; other site
553482009073	active site
553482009074	substrate binding site [chemical binding]; other site
553482009075	CoA binding site [chemical binding]; other site
553482009076	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009077	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 10
553482009078	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.6
553482009079	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 9
553482009080	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
553482009081	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
553482009082	RNase E interface [polypeptide binding]; other site
553482009083	trimer interface [polypeptide binding]; other site
553482009084	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
553482009085	RNase E interface [polypeptide binding]; other site
553482009086	trimer interface [polypeptide binding]; other site
553482009087	active site
553482009088	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
553482009089	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
553482009090	RNA binding site [nucleotide binding]; other site
553482009091	HMMPfam hit to PF00575, S1 RNA binding domain, score 1e-21
553482009092	HMMPfam hit to PF00013, KH domain, score 1.9e-15
553482009093	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 2.4e-25
553482009094	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 1.5e-43
553482009095	HMMPfam hit to PF03726, Polyribonucleotide nucleotidyltransferase,, score 3e-09
553482009096	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 1.8e-13
553482009097	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 2.3e-27
553482009098	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009099	Helix-turn-helix domains; Region: HTH; cl00088
553482009100	HMMPfam hit to PF01527, Transposase, score 0.00051
553482009101	putative transposase OrfB; Reviewed; Region: PHA02517
553482009102	HTH-like domain; Region: HTH_21; pfam13276
553482009103	Integrase core domain; Region: rve; cl01316
553482009104	Integrase core domain; Region: rve_3; cl15866
553482009105	HMMPfam hit to PF00665, Integrase core domain, score 2.2e-37
553482009106	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
553482009107	16S/18S rRNA binding site [nucleotide binding]; other site
553482009108	S13e-L30e interaction site [polypeptide binding]; other site
553482009109	25S rRNA binding site [nucleotide binding]; other site
553482009110	HMMPfam hit to PF00312, Ribosomal protein S15, score 1.9e-34
553482009111	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482009112	TQXA domain; Region: TQXA_dom; TIGR03934
553482009113	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009114	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009115	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009116	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009117	2 transmembrane helices predicted for SEQ1999 by TMHMM2.0 at aa 12-34 and 450-469
553482009118	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1e-15
553482009119	HMMPfam hit to PF02986, Fibronectin binding repeat, score 2.1e-15
553482009120	HMMPfam hit to PF02986, Fibronectin binding repeat, score 6e-13
553482009121	HMMPfam hit to PF02986, Fibronectin binding repeat, score 0.0044
553482009122	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.6e-25
553482009123	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
553482009124	active site
553482009125	catalytic residues [active]
553482009126	metal binding site [ion binding]; metal-binding site
553482009127	HMMPfam hit to PF01327, Polypeptide deformylase, score 2e-86
553482009128	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
553482009129	HMMPfam hit to PF02525, Flavodoxin-like fold, score 3.8e-05
553482009130	HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 4.4e-18
553482009131	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482009132	Helix-turn-helix domains; Region: HTH; cl00088
553482009133	HMMPfam hit to PF01047, MarR family, score 1.4e-21
553482009134	DNA polymerase III PolC; Validated; Region: polC; PRK00448
553482009135	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
553482009136	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
553482009137	generic binding surface II; other site
553482009138	generic binding surface I; other site
553482009139	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482009140	active site
553482009141	substrate binding site [chemical binding]; other site
553482009142	catalytic site [active]
553482009143	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
553482009144	HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 3.2e-191
553482009145	HMMPfam hit to PF02811, PHP domain, score 9.8e-34
553482009146	HMMPfam hit to PF00929, Exonuclease, score 5e-41
553482009147	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3.4e-06
553482009148	Bacterial protein of unknown function (DUF925); Region: DUF925; cl01435
553482009149	HMMPfam hit to PF06042, Bacterial protein of unknown function (DUF92, score 2.6e-78
553482009150	prolyl-tRNA synthetase; Provisional; Region: PRK09194
553482009151	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; Region: class_II_aaRS-like_core; cl00268
553482009152	motif 1; other site
553482009153	dimer interface [polypeptide binding]; other site
553482009154	active site
553482009155	motif 2; other site
553482009156	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
553482009157	putative deacylase active site [active]
553482009158	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; Region: class_II_aaRS-like_core; cl00268
553482009159	active site
553482009160	motif 3; other site
553482009161	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
553482009162	anticodon binding site; other site
553482009163	HMMPfam hit to PF03129, Anticodon binding domain, score 1.6e-18
553482009164	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associa, score 5.5e-35
553482009165	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.4e-46
553482009166	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482009167	RIP metalloprotease RseP; Region: TIGR00054
553482009168	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
553482009169	active site
553482009170	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
553482009171	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
553482009172	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
553482009173	putative substrate binding region [chemical binding]; other site
553482009174	HMMPfam hit to PF02163, Peptidase family M50, score 1.2e-95
553482009175	5 transmembrane helices predicted for SEQ2006 by TMHMM2.0 at aa 4-26, 169-191, 300-322, 343-365 and 392-411
553482009176	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482009177	Cytidylyltransferase family; Region: CTP_transf_1; cl00347
553482009178	HMMPfam hit to PF01148, Cytidylyltransferase family, score 7.9e-95
553482009179	PS01315 Phosphatidate cytidylyltransferase signature.
553482009180	7 transmembrane helices predicted for SEQ2007 by TMHMM2.0 at aa 7-29, 49-68, 80-97, 107-126, 135-157, 172-191 and 196-218
553482009181	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
553482009182	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
553482009183	catalytic residue [active]
553482009184	putative FPP diphosphate  binding site; other site
553482009185	putative FPP binding hydrophobic cleft; other site
553482009186	dimer interface [polypeptide binding]; other site
553482009187	putative IPP diphosphate binding site; other site
553482009188	HMMPfam hit to PF01255, undecaprenyl diphosphate syntha, score 6.4e-109
553482009189	PS01066 Undecaprenyl pyrophosphate synthetase family signature.
553482009190	Preprotein translocase subunit; Region: YajC; cl00806
553482009191	HMMPfam hit to PF02699, Preprotein translocase subunit, score 2.7e-09
553482009192	1 transmembrane helix predicted for SEQ2009 by TMHMM2.0 at aa 5-19
553482009193	CDS contains a nonsense mutation (amber) after codon 17. Similar to Streptococcus pyogenes serotype M6 thioredoxin UniProt:Q5X9U2 (EMBL:CP000003 (124 aa) fasta scores: E()=9.8e-22, 57.391% id in 115 aa
553482009194	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
553482009195	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
553482009196	Ca binding site [ion binding]; other site
553482009197	active site
553482009198	catalytic site [active]
553482009199	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 5.3e-136
553482009200	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
553482009201	The N-terminal ATPase domain of the maltose transporter, MalK.  ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles.  ABC transporters contain two...; Region: ABC_MalK_N; cd03301
553482009202	Walker A/P-loop; other site
553482009203	ATP binding site [chemical binding]; other site
553482009204	Q-loop/lid; other site
553482009205	ABC transporter signature motif; other site
553482009206	Walker B; other site
553482009207	D-loop; other site
553482009208	H-loop/switch region; other site
553482009209	TOBE domain; Region: TOBE_2; cl01440
553482009210	HMMPfam hit to PF08402, TOBE domain, score 2.4e-10
553482009211	HMMPfam hit to PF03459, TOBE domain, score 2.1e-08
553482009212	HMMPfam hit to PF00005, ABC transporter, score 5.3e-57
553482009213	PS00211 ABC transporters family signature.
553482009214	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009215	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
553482009216	Helix-turn-helix domains; Region: HTH; cl00088
553482009217	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 0.0044
553482009218	Staphylokinase/Streptokinase family; Region: Staphylokinase; pfam02821
553482009219	HMMPfam hit to PF02821, Staphylokinase/Streptokinase family, score 4.5e-10
553482009220	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
553482009221	putative active site [active]
553482009222	dimerization interface [polypeptide binding]; other site
553482009223	putative tRNAtyr binding site [nucleotide binding]; other site
553482009224	HMMPfam hit to PF02580, D-Tyr-tRNA(Tyr) deacylase, score 2.1e-80
553482009225	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
553482009226	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
553482009227	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
553482009228	synthetase active site [active]
553482009229	NTP binding site [chemical binding]; other site
553482009230	metal binding site [ion binding]; metal-binding site
553482009231	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
553482009232	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
553482009233	HMMPfam hit to PF01842, ACT domain, score 1.5e-07
553482009234	HMMPfam hit to PF02824, TGS domain, score 1.6e-27
553482009235	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 3.4e-47
553482009236	HMMPfam hit to PF01966, HD domain, score 3.9e-14
553482009237	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482009238	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482009239	HMMPfam hit to PF00746, Gram positive anchor, score 5.2e-12
553482009240	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009241	HMMPfam hit to PF04650, YSIRK type signal peptide, score 4.3e-12
553482009242	YSIRK-targeted surface antigen transcriptional regulator; Region: adjacent_YSIRK; TIGR04094
553482009243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482009244	Predicted helix-turn-helix motif with score 2064.000, SD 6.22 at aa 309-330, sequence VTTAELAQHFNMSESKLRQIFK
553482009245	PS00041 Bacterial regulatory proteins, araC family signature.
553482009246	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-07
553482009247	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
553482009248	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 1.1e-67
553482009249	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
553482009250	putative catalytic site [active]
553482009251	putative metal binding site [ion binding]; other site
553482009252	putative phosphate binding site [ion binding]; other site
553482009253	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 4.4e-09
553482009254	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482009255	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
553482009256	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482009257	active site turn [active]
553482009258	phosphorylation site [posttranslational modification]
553482009259	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
553482009260	HPr interaction site; other site
553482009261	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482009262	active site
553482009263	phosphorylation site [posttranslational modification]
553482009264	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 2.4e-53
553482009265	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482009266	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 3.8e-16
553482009267	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482009268	9 transmembrane helices predicted for SEQ2021 by TMHMM2.0 at aa 20-42, 57-79, 86-108, 141-163, 184-206, 312-329, 341-358, 363-385 and 418-440
553482009269	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3e-45
553482009270	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482009271	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482009272	DNA binding site [nucleotide binding]
553482009273	domain linker motif; other site
553482009274	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
553482009275	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00015
553482009276	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 3.2e-10
553482009277	Predicted helix-turn-helix motif with score 2421.000, SD 7.43 at aa 2-23, sequence VTIKDVARLAGVSPSTASRAIN
553482009278	PS00356 Bacterial regulatory proteins, lacI family signature.
553482009279	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385; cl00611
553482009280	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
553482009281	HMMPfam hit to PF04452, Protein of unknown function (DUF558), score 2.6e-91
553482009282	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
553482009283	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482009284	S-adenosylmethionine binding site [chemical binding]; other site
553482009285	HMMPfam hit to PF06325, Ribosomal protein L11 methyltransfera, score 3e-157
553482009286	HMMPfam hit to PF05175, Methyltransferase small domain, score 7.3e-07
553482009287	HMMPfam hit to PF08241, Methyltransferase domain, score 0.0015
553482009288	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482009289	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482009290	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009291	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 1.3e-05
553482009292	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.0049
553482009293	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_23; cd04682
553482009294	nudix motif; other site
553482009295	HMMPfam hit to PF00293, NUDIX domain, score 4.7e-11
553482009296	ASC-1 homology domain, subfamily similar to Pyrococcus furiosus Pf0470. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_PF0470_like; cd06555
553482009297	HMMPfam hit to PF07060, ProFAR isomerase associated, score 2e-17
553482009298	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
553482009299	aminodeoxychorismate synthase; Provisional; Region: PRK07508
553482009300	chorismate binding enzyme; Region: Chorismate_bind; cl10555
553482009301	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate...; Region: PLPDE_IV; cl00224
553482009302	substrate-cofactor binding pocket; other site
553482009303	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482009304	catalytic residue [active]
553482009305	HMMPfam hit to PF00425, chorismate binding enzyme, score 3.6e-70
553482009306	PS00770 Aminotransferases class-IV signature.
553482009307	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
553482009308	Glutamine amidotransferase class-I; Region: GATase; pfam00117
553482009309	glutamine binding [chemical binding]; other site
553482009310	catalytic triad [active]
553482009311	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 4.7e-66
553482009312	PS00442 Glutamine amidotransferases class-I active site.
553482009313	recombination factor protein RarA; Reviewed; Region: PRK13342
553482009314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482009315	Walker A motif; other site
553482009316	ATP binding site [chemical binding]; other site
553482009317	Walker B motif; other site
553482009318	arginine finger; other site
553482009319	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
553482009320	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.4e-17
553482009321	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00056
553482009322	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009323	putative transposase OrfB; Reviewed; Region: PHA02517
553482009324	HTH-like domain; Region: HTH_21; pfam13276
553482009325	Integrase core domain; Region: rve; cl01316
553482009326	Integrase core domain; Region: rve_3; cl15866
553482009327	HMMPfam hit to PF00665, Integrase core domain, score 7.5e-38
553482009328	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009329	Helix-turn-helix domains; Region: HTH; cl00088
553482009330	HMMPfam hit to PF01527, Transposase, score 0.00051
553482009331	CDS is truncated by the insertion of the downstream prophage. N-terminal region is similar to the N-terminus of Streptococcus pyogenes serotype M18 repressor protein UniProt:Q8P1T3 (EMBL:AE010005 (254 aa) fasta scores: E()=0.00048, 36.232% id in 138 aa
553482009332	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-15
553482009333	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009334	Predicted helix-turn-helix motif with score 1936.000, SD 5.78 at aa 26-47, sequence KTQKELAKLIGVTKQTIINDEK
553482009335	prophage phiSeq4
553482009336	Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123
553482009337	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482009338	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 9e-17
553482009339	PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2.
553482009340	HMMPfam hit to PF01123, Staphylococcal/Streptococcal toxin, O, score 1.6e-29
553482009341	1 transmembrane helix predicted for SEQ2036 by TMHMM2.0 at aa 13-35
553482009342	Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123
553482009343	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482009344	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 1.3e-25
553482009345	PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2.
553482009346	PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1.
553482009347	HMMPfam hit to PF01123, Staphylococcal/Streptococcal toxin, O, score 1.4e-32
553482009348	1 transmembrane helix predicted for SEQ2037 by TMHMM2.0 at aa 13-35
553482009349	NlpC/P60 family; Region: NLPC_P60; cl11438
553482009350	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
553482009351	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
553482009352	active site
553482009353	Bacterial SH3 domain; Region: SH3_3; cl02551
553482009354	HMMPfam hit to PF01183, Glycosyl hydrolases family, score 1.2e-75
553482009355	HMMPfam hit to PF05257, CHAP domain, score 4.2e-30
553482009356	1 transmembrane helix predicted for SEQ2039 by TMHMM2.0 at aa 7-29
553482009357	Bacteriophage holin; Region: Phage_holin_1; cl02344
553482009358	HMMPfam hit to PF04531, Bacteriophage holin, score 6.9e-51
553482009359	1 transmembrane helix predicted for SEQ2040 by TMHMM2.0 at aa 12-30
553482009360	1 transmembrane helix predicted for SEQ2041 by TMHMM2.0 at aa 5-24
553482009361	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482009362	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 6.3e-106
553482009363	gp58-like protein; Region: Gp58; pfam07902
553482009364	HMMPfam hit to PF07902, gp58-like protein, score 0
553482009365	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482009366	Hyaluronidase protein (HylP); Region: Hyaluronidase_1; pfam07212
553482009367	HMMPfam hit to PF07212, Hyaluronidase protein (HylP), score 6e-212
553482009368	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482009369	ribonuclease D; Provisional; Region: PRK10829
553482009370	HMMPfam hit to PF06605, Protein of unknown function (DUF1142), score 0.00056
553482009371	hypothetical protein; Region: PHA01795
553482009372	Phage tail protein; Region: Sipho_tail; pfam05709
553482009373	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009374	tape measure domain; Region: tape_meas_nterm; TIGR02675
553482009375	PS00678 Trp-Asp (WD) repeats signature.
553482009376	4 transmembrane helices predicted for SEQ2048 by TMHMM2.0 at aa 619-641, 648-670, 674-696 and 709-731
553482009377	Phage protein; Region: DUF3647; cl10335
553482009378	Phage major tail protein 2; Region: Phage_tail_2; cl11463
553482009379	HMMPfam hit to PF06199, Phage major tail protein, score 1.3e-91
553482009380	Bacteriophage protein of unknown function (DUF646); Region: DUF646; cl12124
553482009381	HMMPfam hit to PF07772, TP901-1 ORF40-like protein, score 2.3e-37
553482009382	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
553482009383	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
553482009384	1 transmembrane helix predicted for SEQ2059 by TMHMM2.0 at aa 27-49
553482009385	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
553482009386	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
553482009387	HMMPfam hit to PF04233, Phage Mu protein F like protein, score 7.2e-06
553482009388	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482009389	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
553482009390	HMMPfam hit to PF05133, Phage portal protein, SPP1 Gp6-like, score 3.3e-59
553482009391	Phage terminase large subunit; Region: Terminase_3; cl12054
553482009392	Terminase-like family; Region: Terminase_6; pfam03237
553482009393	HMMPfam hit to PF04466, Phage terminase large subunit, score 8e-90
553482009394	HMMPfam hit to PF07570, Protein of unknown function (DUF1545), score 1.3e-21
553482009395	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009396	Terminase small subunit; Region: Terminase_2; cl01513
553482009397	HMMPfam hit to PF03592, Terminase small subunit, score 2.1e-53
553482009398	phage transcriptional activator, RinA family; Region: phage_rinA; TIGR01636
553482009399	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482009400	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 8.4e-41
553482009401	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482009402	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482009403	ATP binding site [chemical binding]; other site
553482009404	putative Mg++ binding site [ion binding]; other site
553482009405	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482009406	nucleotide binding region [chemical binding]; other site
553482009407	ATP-binding site [chemical binding]; other site
553482009408	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.015
553482009409	HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 6.1e-07
553482009410	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
553482009411	Phage associated DNA primase [General function prediction only]; Region: COG3378
553482009412	D5 N terminal like; Region: D5_N; cl07360
553482009413	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
553482009414	HMMPfam hit to PF03288, Poxvirus D5 protein-like, score 3.6e-133
553482009415	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009416	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_A; cd08642
553482009417	active site
553482009418	DNA binding site [nucleotide binding]
553482009419	catalytic site [active]
553482009420	PS00447 DNA polymerase family A signature.
553482009421	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
553482009422	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
553482009423	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009424	CDS contains a frameshift after codon 21 due to a 4 nucleotide deletion. Similar to Streptococcus pyogenes serotype M1 phage protein. UniProt:Q48X51 (EMBL:CP000017 (50 aa) fasta scores: E()=5.3e-17, 96.000% id in 50 aa
553482009425	PS00018 EF-hand calcium-binding domain.
553482009426	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482009427	Predicted helix-turn-helix motif with score 1346.000, SD 3.77 at aa 20-41, sequence IKKSDLAAAYGLNRQEVTNILS
553482009428	1 transmembrane helix predicted for SEQ2084 by TMHMM2.0 at aa 236-258
553482009429	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009430	non-specific DNA binding site [nucleotide binding]; other site
553482009431	salt bridge; other site
553482009432	sequence-specific DNA binding site [nucleotide binding]; other site
553482009433	HMMPfam hit to PF01381, Helix-turn-helix, score 1.7e-08
553482009434	Predicted helix-turn-helix motif with score 1133.000, SD 3.05 at aa 17-38, sequence ITLIQLEETLEYSRNTLYKLKT
553482009435	Domain of unknown function (DUF955); Region: DUF955; cl01076
553482009436	HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 1.8e-17
553482009437	PS00011 Vitamin K-dependent carboxylation domain.
553482009438	Tn1545-related conjugative transposon integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes bacterial (gram positive) and phage integrases, including those similar to Tn1545, Tn5252, and...; Region: INT_Tn1545_C; cd01199
553482009439	Int/Topo IB signature motif; other site
553482009440	HMMPfam hit to PF00589, Phage integrase family, score 2.5e-19
553482009441	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482009442	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482009443	putative transposase OrfB; Reviewed; Region: PHA02517
553482009444	HTH-like domain; Region: HTH_21; pfam13276
553482009445	Integrase core domain; Region: rve; cl01316
553482009446	Integrase core domain; Region: rve_3; cl15866
553482009447	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482009448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009449	Helix-turn-helix domains; Region: HTH; cl00088
553482009450	HMMPfam hit to PF01527, Transposase, score 0.00062
553482009451	HMMPfam hit to PF02178, no description, score 0.21
553482009452	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482009453	CDS is truncated by the insertion of the upstream IS element and lacks an appropriate translational start site
553482009454	11 transmembrane helices predicted for SEQ2094 by TMHMM2.0 at aa 12-34, 44-63, 75-94, 98-120, 140-162, 172-194, 232-254, 264-286, 306-328, 353-375 and 380-402
553482009455	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482009456	topology modulation protein; Provisional; Region: PRK07261
553482009457	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482009458	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009459	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482009460	1 transmembrane helix predicted for SEQ2098 by TMHMM2.0 at aa 6-28
553482009461	CDS contains a nonsense mutation (ochre) after codon 7
553482009462	1 transmembrane helix predicted for SEQ2099 by TMHMM2.0 at aa 5-27
553482009463	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
553482009464	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl01383
553482009465	HMMPfam hit to PF00746, Gram positive anchor, score 4.4e-11
553482009466	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009467	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482009468	HMMPfam hit to PF00746, Gram positive anchor, score 8.5e-10
553482009469	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009470	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.1e-11
553482009471	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 8.6e-13
553482009472	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482009473	catalytic core [active]
553482009474	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 4.5e-34
553482009475	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
553482009476	putative dimer interface [polypeptide binding]; other site
553482009477	catalytic triad [active]
553482009478	HMMPfam hit to PF02016, LD-carboxypeptidase, score 1.5e-39
553482009479	PS00308 Legume lectins alpha-chain signature.
553482009480	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
553482009481	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
553482009482	dimer interface [polypeptide binding]; other site
553482009483	active site
553482009484	metal binding site [ion binding]; metal-binding site
553482009485	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 2.1e-78
553482009486	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
553482009487	active site
553482009488	intersubunit interactions; other site
553482009489	catalytic residue [active]
553482009490	HMMPfam hit to PF00923, Transaldolase, score 9.1e-26
553482009491	PS00958 Transaldolase active site.
553482009492	pyruvate formate-lyase; Region: PFL2-3; TIGR01774
553482009493	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
553482009494	dimer interface [polypeptide binding]; other site
553482009495	active site
553482009496	glycine loop; other site
553482009497	HMMPfam hit to PF01228, Glycine radical, score 3.2e-22
553482009498	PS00850 Glycine radical signature.
553482009499	HMMPfam hit to PF02901, Pyruvate formate lyase, score 2.6e-182
553482009500	PS00063 Aldo/keto reductase family active site signature.
553482009501	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl00557
553482009502	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482009503	10 transmembrane helices predicted for SEQ2107 by TMHMM2.0 at aa 28-50, 70-92, 101-120, 135-157, 186-208, 223-245, 288-310, 347-369, 374-396 and 400-417
553482009504	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.5e-103
553482009505	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009506	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482009507	active site
553482009508	P-loop; other site
553482009509	phosphorylation site [posttranslational modification]
553482009510	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 2.5e-40
553482009511	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482009512	active site
553482009513	methionine cluster; other site
553482009514	phosphorylation site [posttranslational modification]
553482009515	metal binding site [ion binding]; metal-binding site
553482009516	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 1.4e-33
553482009517	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
553482009518	Helix-turn-helix domains; Region: HTH; cl00088
553482009519	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
553482009520	HMMPfam hit to PF04198, sugar-binding domain, score 3.3e-96
553482009521	Predicted helix-turn-helix motif with score 1610.000, SD 4.67 at aa 21-42, sequence KSQTAISKQMNIYRTTVCRMLA
553482009522	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482009523	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482009524	DNA-binding site [nucleotide binding]; DNA binding site
553482009525	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
553482009526	active site
553482009527	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 3.3e-35
553482009528	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 3.6e-19
553482009529	HMMPfam hit to PF08279, HTH domain, score 3.7e-07
553482009530	PS00894 Bacterial regulatory proteins, deoR family signature.
553482009531	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
553482009532	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482009533	FeS/SAM binding site; other site
553482009534	PS00473 Gonadotropin-releasing hormones signature.
553482009535	PS01087 Radical activating enzymes signature.
553482009536	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
553482009537	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
553482009538	GDP-binding site [chemical binding]; other site
553482009539	ACT binding site; other site
553482009540	IMP binding site; other site
553482009541	HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 6.4e-304
553482009542	PS00513 Adenylosuccinate synthetase active site.
553482009543	PS01266 Adenylosuccinate synthetase GTP-binding site.
553482009544	2 transmembrane helices predicted for SEQ2114 by TMHMM2.0 at aa 13-32 and 37-54
553482009545	Uncharacterized protein involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TelA; COG3853
553482009546	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009547	Helix-turn-helix domains; Region: HTH; cl00088
553482009548	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482009549	HMMPfam hit to PF01527, Transposase, score 0.00062
553482009550	HMMPfam hit to PF02178, no description, score 0.21
553482009552	CDS is truncated by the insertion of the upstream IS element and subsequent deletion events. CDS lacks appropriate translational start site. Similar to Streptococcus agalactiae transcriptional regulator, AraC family UniProt:Q3DB93 (EMBL:AAJR01000002 (402 aa) fasta scores: E()=2e-86, 60.825% id in 388 aa
553482009553	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.4e-05
553482009554	Predicted helix-turn-helix motif with score 1451.000, SD 4.13 at aa 310-331, sequence LKVSDIAKHLYISESHLRAVFK
553482009555	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
553482009556	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
553482009557	dimerization interface [polypeptide binding]; other site
553482009558	domain crossover interface; other site
553482009559	redox-dependent activation switch; other site
553482009560	HMMPfam hit to PF01430, Hsp33 protein, score 1.4e-151
553482009561	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
553482009562	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
553482009563	FMN binding site [chemical binding]; other site
553482009564	active site
553482009565	catalytic residues [active]
553482009566	substrate binding site [chemical binding]; other site
553482009567	HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 0.00052
553482009568	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 0.043
553482009569	HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 2.1e-102
553482009570	PS01136 Uncharacterized protein family UPF0034 signature.
553482009571	CDS contains a nonsense mutation (ochre) after codon 119. Similar to Streptococcus pyogenes serotype M1 deoxyguanosine kinase/deoxyadenosine kinase(i) subunit (deoxyadenosine kinase/deoxyguanosine kinase. UniProt:Q9A1S5 (EMBL:AE006482 (213 aa) fasta scores: E()=7.5e-65, 90.610% id in 213 aa
553482009572	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009573	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
553482009574	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482009575	Walker A/P-loop; other site
553482009576	ATP binding site [chemical binding]; other site
553482009577	Q-loop/lid; other site
553482009578	ABC transporter signature motif; other site
553482009579	Walker B; other site
553482009580	D-loop; other site
553482009581	H-loop/switch region; other site
553482009582	HMMPfam hit to PF00005, ABC transporter, score 1.4e-40
553482009583	PS00211 ABC transporters family signature.
553482009584	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009585	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
553482009586	TM-ABC transporter signature motif; other site
553482009587	7 transmembrane helices predicted for SEQ2126 by TMHMM2.0 at aa 10-28, 41-63, 83-105, 129-151, 209-228, 235-257 and 267-282
553482009588	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.1e-21
553482009589	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482009590	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
553482009591	zinc binding site [ion binding]; other site
553482009592	putative ligand binding site [chemical binding]; other site
553482009593	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 4.5e-81
553482009594	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009595	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482009596	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
553482009597	zinc binding site [ion binding]; other site
553482009598	putative ligand binding site [chemical binding]; other site
553482009599	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 5.4e-73
553482009600	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009601	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482009602	dimer interface [polypeptide binding]; other site
553482009603	ssDNA binding site [nucleotide binding]; other site
553482009604	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482009605	HMMPfam hit to PF00436, Single-strand binding protein family, score 1.3e-23
553482009606	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482009607	S-adenosylmethionine binding site [chemical binding]; other site
553482009608	HMMPfam hit to PF08241, Methyltransferase domain, score 8.8e-15
553482009609	HMMPfam hit to PF08242, Methyltransferase domain, score 2e-11
553482009610	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
553482009611	putative tRNA-binding site [nucleotide binding]; other site
553482009612	HMMPfam hit to PF01588, tRNA binding domain, score 9.2e-18
553482009613	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
553482009614	catalytic residues [active]
553482009615	HMMPfam hit to PF00085, Thioredoxin, score 2.7e-05
553482009616	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
553482009617	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
553482009618	metal binding site [ion binding]; metal-binding site
553482009619	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482009620	HMMPfam hit to PF05343, M42 glutamyl aminopeptidase, score 1.6e-133
553482009621	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482009622	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
553482009623	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.003
553482009624	HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depe, score 2.4e-51
553482009625	PS00521 Delta 1-pyrroline-5-carboxylate reductase signature.
553482009626	4 transmembrane helices predicted for SEQ2136 by TMHMM2.0 at aa 21-43, 47-69, 96-118 and 122-141
553482009627	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009628	CAAX protease self-immunity; Region: Abi; cl00558
553482009629	7 transmembrane helices predicted for SEQ2137 by TMHMM2.0 at aa 17-36, 46-68, 81-103, 116-138, 151-173, 177-194 and 201-223
553482009630	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 5.8e-18
553482009631	CDS contains a frameshift after codon 69. Similar to Streptococcus mutans hypothetical protein UniProt:Q8DS59 (EMBL:AE014133 (146 aa) fasta scores: E()=2.9e-13, 36.429% id in 140 aa
553482009632	2 transmembrane helices predicted for SEQ2138 by TMHMM2.0 at aa 33-55 and 59-81
553482009633	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009634	2 transmembrane helices predicted for SEQ2139 by TMHMM2.0 at aa 21-43 and 47-69
553482009635	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009636	non-specific DNA binding site [nucleotide binding]; other site
553482009637	salt bridge; other site
553482009638	sequence-specific DNA binding site [nucleotide binding]; other site
553482009639	HMMPfam hit to PF01381, Helix-turn-helix, score 6.9e-17
553482009640	Predicted helix-turn-helix motif with score 2084.000, SD 6.28 at aa 14-35, sequence ISQADLADMMCVTRQTIISLEK
553482009641	Protein of unknown function (DUF328); Region: DUF328; cl01143
553482009642	HMMPfam hit to PF03883, Protein of unknown function (DUF328), score 3.3e-85
553482009643	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
553482009644	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482009645	FeS/SAM binding site; other site
553482009646	Predicted acetyltransferase [General function prediction only]; Region: COG3981
553482009647	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482009648	Coenzyme A binding pocket [chemical binding]; other site
553482009649	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-11
553482009650	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
553482009651	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482009652	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 4.5e-14
553482009653	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
553482009654	ATP cone domain; Region: ATP-cone; pfam03477
553482009655	Class III ribonucleotide reductase; Region: RNR_III; cd01675
553482009656	effector binding site; other site
553482009657	active site
553482009658	Zn binding site [ion binding]; other site
553482009659	glycine loop; other site
553482009660	HMMPfam hit to PF01228, Glycine radical, score 2.8e-30
553482009661	PS00850 Glycine radical signature.
553482009662	HMMPfam hit to PF03477, ATP cone domain, score 5.5e-29
553482009663	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
553482009664	11 transmembrane helices predicted for SEQ2147 by TMHMM2.0 at aa 35-57, 90-112, 125-147, 152-174, 186-200, 204-221, 228-250, 276-298, 311-330, 340-362 and 382-404
553482009665	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
553482009666	Protein of unknown function (DUF1292); Region: DUF1292; cl01608
553482009667	HMMPfam hit to PF06949, Protein of unknown function (DUF1292), score 4.3e-55
553482009668	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination.  HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes...; Region: RuvC_resolvase; cl00243
553482009669	HMMPfam hit to PF03652, Uncharacterised protein family (UPF0081), score 2.2e-51
553482009670	Bacterial protein of unknown function (DUF965); Region: DUF965; cl01857
553482009671	HMMPfam hit to PF06135, Bacterial protein of unknown function (DUF96, score 4.8e-51
553482009672	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
553482009673	ArsC family; Region: ArsC; pfam03960
553482009674	putative catalytic residues [active]
553482009675	thiol/disulfide switch; other site
553482009676	HMMPfam hit to PF03960, ArsC family, score 1.5e-53
553482009677	recombinase A; Provisional; Region: recA; PRK09354
553482009678	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
553482009679	hexamer interface [polypeptide binding]; other site
553482009680	Walker A motif; other site
553482009681	ATP binding site [chemical binding]; other site
553482009682	Walker B motif; other site
553482009683	HMMPfam hit to PF00154, recA bacterial DNA recombination protein, score 2.3e-234
553482009684	PS00321 recA signature.
553482009685	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009686	competence damage-inducible protein A; Provisional; Region: PRK00549
553482009687	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
553482009688	putative MPT binding site; other site
553482009689	Competence-damaged protein; Region: CinA; cl00666
553482009690	HMMPfam hit to PF02464, Competence-damaged protein, score 2.7e-64
553482009691	HMMPfam hit to PF00994, molybdopterin binding domain, score 5.3e-47
553482009692	3 transmembrane helices predicted for SEQ2154 by TMHMM2.0 at aa 7-29, 39-61 and 68-90
553482009693	PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; Region: PLA2_like; cl05417
553482009694	primary metal binding site; other site
553482009695	catalytic residues [active]
553482009696	1 transmembrane helix predicted for SEQ2155 by TMHMM2.0 at aa 13-35
553482009697	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009698	non-specific DNA binding site [nucleotide binding]; other site
553482009699	salt bridge; other site
553482009700	sequence-specific DNA binding site [nucleotide binding]; other site
553482009701	HMMPfam hit to PF01381, Helix-turn-helix, score 2.9e-06
553482009702	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
553482009703	HMMPfam hit to PF03352, Methyladenine glycosylase, score 3.7e-88
553482009704	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
553482009705	RuvA N terminal domain; Region: RuvA_N; pfam01330
553482009706	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
553482009707	HMMPfam hit to PF07499, RuvA, C-terminal domain, score 5.8e-17
553482009708	HMMPfam hit to PF01330, RuvA N terminal domain, score 9.8e-26
553482009709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482009710	Major Facilitator Superfamily; Region: MFS_1; pfam07690
553482009711	putative substrate translocation pore; other site
553482009712	12 transmembrane helices predicted for SEQ2159 by TMHMM2.0 at aa 16-35, 40-62, 75-93, 98-120, 141-160, 165-187, 218-236, 256-278, 291-310, 314-336, 349-371 and 381-400
553482009713	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009714	PS00216 Sugar transport proteins signature 1.
553482009715	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
553482009716	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482009717	ATP binding site [chemical binding]; other site
553482009718	Mg2+ binding site [ion binding]; other site
553482009719	G-X-G motif; other site
553482009720	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
553482009721	ATP binding site [chemical binding]; other site
553482009722	MutL C terminal dimerisation domain; Region: MutL_C; cl07336
553482009723	HMMPfam hit to PF01119, DNA mismatch repair protein, C-termina, score 1e-40
553482009724	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 2.6e-06
553482009725	PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature.
553482009726	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
553482009727	MutS domain I; Region: MutS_I; pfam01624
553482009728	MutS domain II; Region: MutS_II; pfam05188
553482009729	MutS family domain IV; Region: MutS_IV; pfam05190
553482009730	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482009731	Walker A/P-loop; other site
553482009732	ATP binding site [chemical binding]; other site
553482009733	Q-loop/lid; other site
553482009734	ABC transporter signature motif; other site
553482009735	Walker B; other site
553482009736	D-loop; other site
553482009737	H-loop/switch region; other site
553482009738	HMMPfam hit to PF00488, MutS domain V, score 2.6e-151
553482009739	PS00486 DNA mismatch repair proteins mutS family signature.
553482009740	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009741	HMMPfam hit to PF05192, MutS domain III, score 1.1e-93
553482009742	HMMPfam hit to PF05190, MutS family domain IV, score 2.3e-37
553482009743	HMMPfam hit to PF05188, MutS domain II, score 5.2e-28
553482009744	HMMPfam hit to PF01624, MutS domain I, score 1.6e-70
553482009745	Protein of unknown function (DUF964); Region: DUF964; cl01483
553482009746	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482009747	arginine repressor; Region: argR_whole; TIGR01529
553482009748	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
553482009749	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 1.1e-24
553482009750	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 1.1e-24
553482009751	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
553482009752	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; cl04104
553482009753	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
553482009754	active site
553482009755	HIGH motif; other site
553482009756	KMSK motif region; other site
553482009757	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
553482009758	tRNA binding surface [nucleotide binding]; other site
553482009759	anticodon binding site; other site
553482009760	HMMPfam hit to PF03485, Arginyl tRNA synthetase N terminal do, score 1.9e-29
553482009761	HMMPfam hit to PF00750, tRNA synthetases class I (R), score 4.3e-101
553482009762	HMMPfam hit to PF05746, DALR anticodon binding domain, score 7e-50
553482009763	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
553482009764	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482009765	ABC transporter; Region: ABC_tran_2; pfam12848
553482009766	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
553482009767	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482009768	HMMPfam hit to PF00005, ABC transporter, score 3.9e-25
553482009769	PS00211 ABC transporters family signature.
553482009770	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009771	HMMPfam hit to PF00005, ABC transporter, score 2.7e-20
553482009772	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009773	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009774	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009775	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009776	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; cl10498
553482009777	6 transmembrane helices predicted for SEQ2166 by TMHMM2.0 at aa 13-30, 40-62, 74-96, 111-133, 153-172 and 177-199
553482009778	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.3e-22
553482009779	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 4.9e-25
553482009780	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009781	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009782	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009783	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; cl10498
553482009784	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.8e-17
553482009785	5 transmembrane helices predicted for SEQ2167 by TMHMM2.0 at aa 12-34, 49-71, 78-95, 110-132 and 156-178
553482009786	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 6.4e-20
553482009787	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009788	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009789	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009790	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; cl10498
553482009791	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 3.6e-26
553482009792	5 transmembrane helices predicted for SEQ2168 by TMHMM2.0 at aa 41-63, 83-105, 112-130, 140-162 and 183-205
553482009793	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.8e-23
553482009794	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
553482009795	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
553482009796	dimer interface [polypeptide binding]; other site
553482009797	anticodon binding site; other site
553482009798	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of the...; Region: AspRS_core; cd00777
553482009799	homodimer interface [polypeptide binding]; other site
553482009800	motif 1; other site
553482009801	active site
553482009802	motif 2; other site
553482009803	GAD domain; Region: GAD; pfam02938
553482009804	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of the...; Region: AspRS_core; cd00777
553482009805	motif 3; other site
553482009806	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 2.8e-216
553482009807	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482009808	HMMPfam hit to PF02938, GAD domain, score 2.2e-33
553482009809	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482009810	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 4.5e-23
553482009811	ABC-2 type transporter; Region: ABC2_membrane; cl11417
553482009812	6 transmembrane helices predicted for SEQ2170 by TMHMM2.0 at aa 25-47, 57-79, 100-122, 137-159, 166-185 and 219-241
553482009813	HMMPfam hit to PF01061, ABC-2 type transporter, score 0.00031
553482009814	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482009815	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482009816	Walker A/P-loop; other site
553482009817	ATP binding site [chemical binding]; other site
553482009818	Q-loop/lid; other site
553482009819	ABC transporter signature motif; other site
553482009820	Walker B; other site
553482009821	D-loop; other site
553482009822	H-loop/switch region; other site
553482009823	HMMPfam hit to PF00005, ABC transporter, score 4.3e-38
553482009824	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009825	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482009826	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482009827	active site
553482009828	phosphorylation site [posttranslational modification]
553482009829	intermolecular recognition site; other site
553482009830	dimerization interface [polypeptide binding]; other site
553482009831	LytTr DNA-binding domain; Region: LytTR; cl04498
553482009832	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.2e-10
553482009833	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 2.9e-15
553482009834	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
553482009835	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482009836	7 transmembrane helices predicted for SEQ2173 by TMHMM2.0 at aa 5-23, 36-53, 57-79, 86-108, 118-137, 157-179 and 189-211
553482009837	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
553482009838	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: HisRS-like_core; cd00773
553482009839	dimer interface [polypeptide binding]; other site
553482009840	motif 1; other site
553482009841	active site
553482009842	motif 2; other site
553482009843	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
553482009844	anticodon binding site; other site
553482009845	HMMPfam hit to PF03129, Anticodon binding domain, score 9.2e-16
553482009846	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482009847	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 2.9e-57
553482009848	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009849	Ribosomal L32p protein family; Region: Ribosomal_L32p; cl09115
553482009850	HMMPfam hit to PF01783, Ribosomal L32p protein family, score 8.2e-21
553482009851	Ribosomal protein L33; Region: Ribosomal_L33; cl00383
553482009852	HMMPfam hit to PF00471, Ribosomal protein L33, score 1e-17
553482009853	Protein of unknown function (DUF4065); Region: DUF4065; cl01445
553482009854	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
553482009855	metal binding triad [ion binding]; metal-binding site
553482009856	IncA protein; Region: IncA; pfam04156
553482009857	B-cell receptor-associated protein 31-like; Region: Bap31; cl02219
553482009858	HMMPfam hit to PF00746, Gram positive anchor, score 3.1e-05
553482009859	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009860	1 transmembrane helix predicted for SEQ2180 by TMHMM2.0 at aa 594-616
553482009861	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009862	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
553482009863	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
553482009864	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
553482009865	9 transmembrane helices predicted for SEQ2181 by TMHMM2.0 at aa 21-43, 124-143, 155-177, 181-203, 216-238, 243-265, 278-297, 301-323 and 335-357
553482009866	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482009867	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
553482009868	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482009869	active site
553482009870	phosphorylation site [posttranslational modification]
553482009871	intermolecular recognition site; other site
553482009872	dimerization interface [polypeptide binding]; other site
553482009873	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
553482009874	DNA binding residues [nucleotide binding]
553482009875	dimerization interface [polypeptide binding]; other site
553482009876	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-18
553482009877	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 7.2e-14
553482009878	Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 154-175, sequence YSNEKISKKLYISRRTVDTHVS
553482009879	Pseudomonas avirulence D protein (AvrD); Region: AvrD; pfam05655
553482009880	HMMPfam hit to PF05655, Pseudomonas avirulence D protein (AvrD), score 1.2e-09
553482009881	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009882	putative transposase OrfB; Reviewed; Region: PHA02517
553482009883	HTH-like domain; Region: HTH_21; pfam13276
553482009884	Integrase core domain; Region: rve; cl01316
553482009885	Integrase core domain; Region: rve_3; cl15866
553482009886	HMMPfam hit to PF00665, Integrase core domain, score 4.8e-37
553482009887	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009888	Helix-turn-helix domains; Region: HTH; cl00088
553482009889	HMMPfam hit to PF01527, Transposase, score 0.00051
553482009890	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009891	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482009892	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
553482009893	Walker A/P-loop; other site
553482009894	ATP binding site [chemical binding]; other site
553482009895	Q-loop/lid; other site
553482009896	ABC transporter signature motif; other site
553482009897	Walker B; other site
553482009898	D-loop; other site
553482009899	H-loop/switch region; other site
553482009900	HMMPfam hit to PF00005, ABC transporter, score 4.6e-61
553482009901	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009902	PS00211 ABC transporters family signature.
553482009903	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
553482009904	FtsX-like permease family; Region: FtsX; cl15850
553482009905	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
553482009906	FtsX-like permease family; Region: FtsX; cl15850
553482009907	8 transmembrane helices predicted for SEQ2189 by TMHMM2.0 at aa 32-54, 273-295, 315-337, 360-382, 437-459, 641-663, 690-712 and 732-754
553482009908	HMMPfam hit to PF02687, Predicted permease, score 8.3e-21
553482009909	HMMPfam hit to PF02687, Predicted permease, score 6.7e-16
553482009910	IncA protein; Region: IncA; pfam04156
553482009911	B-cell receptor-associated protein 31-like; Region: Bap31; cl02219
553482009912	Gram positive anchor; Region: Gram_pos_anchor; cl15427
553482009913	2 transmembrane helices predicted for SEQ2190 by TMHMM2.0 at aa 21-38 and 641-663
553482009914	HMMPfam hit to PF00746, Gram positive anchor, score 5.8e-06
553482009915	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009916	Domain of unknown function (DUF368); Region: DUF368; cl00893
553482009917	HMMPfam hit to PF04018, Domain of unknown function (DUF368), score 1e-107
553482009918	8 transmembrane helices predicted for SEQ2191 by TMHMM2.0 at aa 13-35, 48-70, 80-102, 115-137, 152-174, 186-204, 219-236 and 249-271
553482009919	HMMPfam hit to PF00293, NUDIX domain, score 1.4e-07
553482009920	PS00893 mutT domain signature.
553482009921	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009922	Helix-turn-helix domains; Region: HTH; cl00088
553482009923	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482009924	HMMPfam hit to PF01527, Transposase, score 0.00062
553482009925	HMMPfam hit to PF02178, no description, score 0.21
553482009926	putative transposase OrfB; Reviewed; Region: PHA02517
553482009927	HTH-like domain; Region: HTH_21; pfam13276
553482009928	Integrase core domain; Region: rve; cl01316
553482009929	Integrase core domain; Region: rve_3; cl15866
553482009930	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482009931	Helix-turn-helix domains; Region: HTH; cl00088
553482009932	HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 1.9e-18
553482009933	Protein of unknown function (DUF1700); Region: DUF1700; cl01933
553482009934	Protein of unknown function (DUF1700); Region: DUF1700; cl01933
553482009935	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
553482009936	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
553482009937	Predicted membrane protein [Function unknown]; Region: COG1511
553482009938	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
553482009939	ABC-2 type transporter; Region: ABC2_membrane; cl11417
553482009940	6 transmembrane helices predicted for SEQ2199 by TMHMM2.0 at aa 13-35, 577-599, 619-641, 651-670, 675-697 and 730-752
553482009941	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482009942	Helix-turn-helix domains; Region: HTH; cl00088
553482009943	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.6e-05
553482009944	Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 28-49, sequence VTTVQLAKMAGISRSSFYTHYK
553482009945	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
553482009946	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
553482009947	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482009948	RNA binding surface [nucleotide binding]; other site
553482009949	HMMPfam hit to PF01479, S4 domain, score 1.8e-23
553482009950	PS00632 Ribosomal protein S4 signature.
553482009951	HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domai, score 5.9e-26
553482009952	Protein of unknown function (DUF1021); Region: DUF1021; cl01852
553482009953	HMMPfam hit to PF06257, Protein of unknown function (DUF1021), score 4.8e-40
553482009954	replicative DNA helicase; Provisional; Region: PRK05748
553482009955	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
553482009956	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
553482009957	Walker A motif; other site
553482009958	ATP binding site [chemical binding]; other site
553482009959	Walker B motif; other site
553482009960	DNA binding loops [nucleotide binding]
553482009961	HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 1.9e-136
553482009962	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009963	HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 5e-47
553482009964	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
553482009965	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
553482009966	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
553482009967	HMMPfam hit to PF03948, Ribosomal protein L9, C-terminal domai, score 1.3e-16
553482009968	HMMPfam hit to PF01281, Ribosomal protein L9, N-terminal domai, score 9.6e-18
553482009969	PS00651 Ribosomal protein L9 signature.
553482009970	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
553482009971	DHH family; Region: DHH; pfam01368
553482009972	DHHA1 domain; Region: DHHA1; pfam02272
553482009973	HMMPfam hit to PF02272, DHHA1 domain, score 1.2e-12
553482009974	HMMPfam hit to PF01368, DHH family, score 6.7e-41
553482009975	2 transmembrane helices predicted for SEQ2205 by TMHMM2.0 at aa 4-26 and 33-52
553482009976	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
553482009977	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482009978	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
553482009979	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 2.7e-263
553482009980	PS01281 Glucose inhibited division protein A family signature 2.
553482009981	PS01280 Glucose inhibited division protein A family signature 1.
553482009982	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
553482009983	nudix motif; other site
553482009984	HMMPfam hit to PF00293, NUDIX domain, score 1.3e-10
553482009985	PS00893 mutT domain signature.
553482009986	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
553482009987	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
553482009988	HMMPfam hit to PF01171, PP-loop family, score 0.074
553482009989	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
553482009990	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
553482009991	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
553482009992	putative L-serine binding site [chemical binding]; other site
553482009993	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 1.6e-50
553482009994	HMMPfam hit to PF01842, ACT domain, score 3e-07
553482009995	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
553482009996	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
553482009997	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 2.9e-107
553482009998	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482009999	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010000	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
553482010001	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482010002	motif II; other site
553482010003	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.9e-15
553482010004	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482010005	HMMPfam hit to PF06737, Transglycosylase-like domain, score 1.2e-19
553482010006	1 transmembrane helix predicted for SEQ2212 by TMHMM2.0 at aa 12-31
553482010007	Cobalt transport protein; Region: CbiQ; cl00463
553482010008	4 transmembrane helices predicted for SEQ2213 by TMHMM2.0 at aa 25-57, 72-94, 106-128 and 245-262
553482010009	HMMPfam hit to PF02361, Cobalt transport protein, score 2.8e-64
553482010010	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13649
553482010011	Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota.  The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed.  This ABC...; Region: ABC_cobalt_CbiO_domain1; cd03225
553482010012	Walker A/P-loop; other site
553482010013	ATP binding site [chemical binding]; other site
553482010014	Q-loop/lid; other site
553482010015	ABC transporter signature motif; other site
553482010016	Walker B; other site
553482010017	D-loop; other site
553482010018	H-loop/switch region; other site
553482010019	HMMPfam hit to PF00005, ABC transporter, score 7.3e-55
553482010020	PS00211 ABC transporters family signature.
553482010021	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010022	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13650
553482010023	Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota.  The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed.  This ABC...; Region: ABC_cobalt_CbiO_domain1; cd03225
553482010024	Walker A/P-loop; other site
553482010025	ATP binding site [chemical binding]; other site
553482010026	Q-loop/lid; other site
553482010027	ABC transporter signature motif; other site
553482010028	Walker B; other site
553482010029	D-loop; other site
553482010030	H-loop/switch region; other site
553482010031	HMMPfam hit to PF00005, ABC transporter, score 4.5e-58
553482010032	PS00211 ABC transporters family signature.
553482010033	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010034	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
553482010035	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 1.4e-36
553482010036	3 transmembrane helices predicted for SEQ2216 by TMHMM2.0 at aa 21-43, 78-100 and 140-162
553482010037	PS00379 CDP-alcohol phosphatidyltransferases signature.
553482010038	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
553482010039	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
553482010040	1 transmembrane helix predicted for SEQ2217 by TMHMM2.0 at aa 172-194
553482010041	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482010042	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
553482010043	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482010044	Uncharacterized protein family (UPF0160); Region: UPF0160; cl01749
553482010045	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 1.2e-15
553482010046	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 1.8e-08
553482010047	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482010048	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482010049	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 5.3e-28
553482010050	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
553482010051	HMMPfam hit to PF01479, S4 domain, score 0.0089
553482010052	recombination protein F; Reviewed; Region: recF; PRK00064
553482010053	RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage.  When replication is prematurely disrupted by DNA damage, several recF pathway gene products play critical roles processing the arrested replication...; Region: ABC_RecF; cd03242
553482010054	Walker A/P-loop; other site
553482010055	ATP binding site [chemical binding]; other site
553482010056	Q-loop/lid; other site
553482010057	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482010058	ABC transporter signature motif; other site
553482010059	Walker B; other site
553482010060	D-loop; other site
553482010061	H-loop/switch region; other site
553482010062	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.5e-09
553482010063	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010064	PS00617 RecF protein signature 1.
553482010065	PS00618 RecF protein signature 2.
553482010066	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
553482010067	9 transmembrane helices predicted for SEQ2222 by TMHMM2.0 at aa 5-22, 32-51, 58-80, 114-133, 153-175, 179-200, 207-229, 234-256 and 268-285
553482010068	HMMPfam hit to PF06800, Sugar transport protein, score 8e-154
553482010069	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is 'interfacial activation', the process of becoming...; Region: Lipase; cl14883
553482010070	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482010071	Helix-turn-helix domains; Region: HTH; cl00088
553482010072	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482010073	HMMPfam hit to PF01527, Transposase, score 0.00062
553482010074	HMMPfam hit to PF02178, no description, score 0.21
553482010076	1 transmembrane helix predicted for SEQ2227 by TMHMM2.0 at aa 4-21
553482010077	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
553482010078	HMMPfam hit to PF07006, Protein of unknown function (DUF1310), score 5.7e-21
553482010079	1 transmembrane helix predicted for SEQ2228 by TMHMM2.0 at aa 21-43
553482010080	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
553482010081	HMMPfam hit to PF07006, Protein of unknown function (DUF1310), score 6.1e-23
553482010082	1 transmembrane helix predicted for SEQ2229 by TMHMM2.0 at aa 4-23
553482010083	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
553482010084	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
553482010085	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key...; Region: CBS_pair_IMPDH; cd04601
553482010086	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine...; Region: IMPDH; cd00381
553482010087	active site
553482010088	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 2.9e-241
553482010089	HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 0.0052
553482010090	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 0.0046
553482010091	PS00487 IMP dehydrogenase / GMP reductase signature.
553482010092	HMMPfam hit to PF00571, CBS domain pair, score 1.8e-28
553482010093	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
553482010094	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
553482010095	active site
553482010096	HIGH motif; other site
553482010097	dimer interface [polypeptide binding]; other site
553482010098	KMSKS motif; other site
553482010099	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 7.2e-84
553482010100	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482010101	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482010102	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482010103	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482010104	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; cl10498
553482010105	5 transmembrane helices predicted for SEQ2232 by TMHMM2.0 at aa 5-27, 47-69, 103-122, 142-164 and 171-190
553482010106	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 9.9e-23
553482010107	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 5.8e-21
553482010108	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
553482010109	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
553482010110	Walker A/P-loop; other site
553482010111	ATP binding site [chemical binding]; other site
553482010112	Q-loop/lid; other site
553482010113	ABC transporter signature motif; other site
553482010114	Walker B; other site
553482010115	D-loop; other site
553482010116	H-loop/switch region; other site
553482010117	ABC transporter; Region: ABC_tran_2; pfam12848
553482010118	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
553482010119	HMMPfam hit to PF00005, ABC transporter, score 3.3e-44
553482010120	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010121	HMMPfam hit to PF00005, ABC transporter, score 8.4e-19
553482010122	PS00211 ABC transporters family signature.
553482010123	Predicted membrane protein [Function unknown]; Region: COG4485
553482010124	14 transmembrane helices predicted for SEQ2234 by TMHMM2.0 at aa 13-35, 77-99, 106-125, 135-152, 159-178, 193-215, 228-250, 290-312, 319-336, 351-373, 378-400, 405-427, 434-456 and 831-853
553482010125	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010126	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010127	Uncharacterized conserved protein [Function unknown]; Region: COG1576; cl00679
553482010128	Predicted SPOUT methyltransferase; Region: SPOUT_MTase; pfam02590
553482010129	HMMPfam hit to PF02590, Uncharacterized ACR, COG1576, score 2.2e-92
553482010130	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cl00149
553482010131	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
553482010132	protein binding site [polypeptide binding]; other site
553482010133	1 transmembrane helix predicted for SEQ2237 by TMHMM2.0 at aa 10-32
553482010134	HMMPfam hit to PF00089, Trypsin, score 7e-16
553482010135	ParB-like nuclease domain; Region: ParBc; cl02129
553482010136	ParB-like partition proteins; Region: parB_part; TIGR00180
553482010137	KorB domain; Region: KorB; pfam08535
553482010138	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.1e-36
553482010139	Predicted helix-turn-helix motif with score 1642.000, SD 4.78 at aa 119-140, sequence MTHEDIATYMGKSRPYISNTIR