-- dump date 20120504_162753 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003875603.1 307066637 9728302 197..1558 1 NC_014494.1 Operon 1 Gene 1 COG0593 ATPase involved in DNA replication initiation; DNA replication initiation ATPase 1558 9728302 SPAP_0001 Streptococcus pneumoniae AP200 DNA replication initiation ATPase YP_003875603.1 197 D 574093 CDS YP_003875604.1 307066638 9726019 1717..2853 1 NC_014494.1 Operon 1 Gene 2 COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase sliding clamp subunit 2853 9726019 SPAP_0002 Streptococcus pneumoniae AP200 DNA polymerase sliding clamp subunit YP_003875604.1 1717 D 574093 CDS YP_003875605.1 307066639 9726020 2918..3112 1 NC_014494.1 Operon 2 Gene 1 COG4481 Uncharacterized protein conserved in bacteria; hypothetical protein 3112 9726020 SPAP_0003 Streptococcus pneumoniae AP200 hypothetical protein YP_003875605.1 2918 D 574093 CDS YP_003875606.1 307066640 9726021 3196..4311 1 NC_014494.1 Operon 3 Gene 1 COG0012 Predicted GTPase, probable translation factor; putative GTPase, probable translation factor 4311 9726021 SPAP_0004 Streptococcus pneumoniae AP200 putative GTPase, probable translation factor YP_003875606.1 3196 D 574093 CDS YP_003875607.1 307066641 9726022 4382..4951 1 NC_014494.1 Operon 3 Gene 2 COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 4951 9726022 SPAP_0005 Streptococcus pneumoniae AP200 peptidyl-tRNA hydrolase YP_003875607.1 4382 D 574093 CDS YP_003875608.1 307066642 9726023 4952..8461 1 NC_014494.1 Operon 3 Gene 3 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 8461 9726023 SPAP_0006 Streptococcus pneumoniae AP200 transcription-repair coupling factor YP_003875608.1 4952 D 574093 CDS YP_003875609.1 307066643 9726024 8519..8785 1 NC_014494.1 Operon 3 Gene 4 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosome-associated heat shock protein 8785 9726024 SPAP_0007 Streptococcus pneumoniae AP200 ribosome-associated heat shock protein YP_003875609.1 8519 D 574093 CDS YP_003875610.1 307066644 9726025 8778..9146 1 NC_014494.1 Operon 3 Gene 5 COG2919 Septum formation initiator; septum formation initiator 9146 9726025 SPAP_0008 Streptococcus pneumoniae AP200 septum formation initiator YP_003875610.1 8778 D 574093 CDS YP_003875611.1 307066645 9726026 9151..9273 1 NC_014494.1 Operon 3 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 9273 9726026 SPAP_0009 Streptococcus pneumoniae AP200 hypothetical protein YP_003875611.1 9151 D 574093 CDS YP_003875612.1 307066646 9726027 9266..10534 1 NC_014494.1 Operon 3 Gene 7 COG2367 Beta-lactamase class A; beta-lactamase class A 10534 9726027 SPAP_0010 Streptococcus pneumoniae AP200 beta-lactamase class A YP_003875612.1 9266 D 574093 CDS YP_003875613.1 307066647 9726028 10531..11808 1 NC_014494.1 Operon 3 Gene 8 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; putative ATPase 11808 9726028 SPAP_0011 Streptococcus pneumoniae AP200 putative ATPase YP_003875613.1 10531 D 574093 CDS YP_003875614.1 307066648 9726029 11812..12354 1 NC_014494.1 Operon 3 Gene 9 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 12354 9726029 SPAP_0012 Streptococcus pneumoniae AP200 hypoxanthine-guanine phosphoribosyltransferase YP_003875614.1 11812 D 574093 CDS YP_003875615.1 307066649 9726030 12370..14328 1 NC_014494.1 Operon 3 Gene 10 COG0465 ATP-dependent Zn proteases; ATP-dependent Zn protease 14328 9726030 SPAP_0013 Streptococcus pneumoniae AP200 ATP-dependent Zn protease YP_003875615.1 12370 D 574093 CDS YP_003875616.1 307066650 9726031 14450..14713 1 NC_014494.1 Operon 4 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 14713 9726031 SPAP_0014 Streptococcus pneumoniae AP200 hypothetical protein YP_003875616.1 14450 D 574093 CDS YP_003875617.1 307066651 9726038 complement(20410..20727) 1 NC_014494.1 Operon 5 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein 20727 9726038 SPAP_0021 Streptococcus pneumoniae AP200 transposase-like protein YP_003875617.1 20410 R 574093 CDS YP_003875618.1 307066652 9726039 complement(20951..21157) 1 NC_014494.1 Operon 6 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein 21157 9726039 SPAP_0022 Streptococcus pneumoniae AP200 transposase-like protein YP_003875618.1 20951 R 574093 CDS YP_003875619.1 307066653 9726040 21473..21709 1 NC_014494.1 Operon 7 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 21709 9726040 SPAP_0023 Streptococcus pneumoniae AP200 hypothetical protein YP_003875619.1 21473 D 574093 CDS YP_003875620.1 307066654 9726041 21898..23226 1 NC_014494.1 Operon 7 Gene 2 COG0104 Adenylosuccinate synthase; adenylosuccinate synthase 23226 9726041 SPAP_0024 Streptococcus pneumoniae AP200 adenylosuccinate synthase YP_003875620.1 21898 D 574093 CDS YP_003875621.1 307066655 9726042 complement(23468..24616) 1 NC_014494.1 Operon 8 Gene 1 COG0582 Integrase; integrase 24616 9726042 SPAP_0025 Streptococcus pneumoniae AP200 integrase YP_003875621.1 23468 R 574093 CDS YP_003875622.1 307066656 9726043 complement(24787..25587) 1 NC_014494.1 Operon 9 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 25587 9726043 SPAP_0026 Streptococcus pneumoniae AP200 hypothetical protein YP_003875622.1 24787 R 574093 CDS YP_003875623.1 307066657 9726044 complement(25714..26469) 1 NC_014494.1 Operon 9 Gene 2 COG2932 Predicted transcriptional regulator; putative transcriptional regulator 26469 9726044 SPAP_0027 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003875623.1 25714 R 574093 CDS YP_003875624.1 307066658 9726045 26643..26849 1 NC_014494.1 Operon 10 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 26849 9726045 SPAP_0028 Streptococcus pneumoniae AP200 hypothetical protein YP_003875624.1 26643 D 574093 CDS YP_003875625.1 307066659 9726046 26871..27032 1 NC_014494.1 hypothetical protein 27032 9726046 SPAP_0029 Streptococcus pneumoniae AP200 hypothetical protein YP_003875625.1 26871 D 574093 CDS YP_003875626.1 307066660 9726047 27066..27194 1 NC_014494.1 Operon 11 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 27194 9726047 SPAP_0030 Streptococcus pneumoniae AP200 hypothetical protein YP_003875626.1 27066 D 574093 CDS YP_003875627.1 307066661 9726048 complement(27157..27834) 1 NC_014494.1 Operon 12 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 27834 9726048 SPAP_0031 Streptococcus pneumoniae AP200 hypothetical protein YP_003875627.1 27157 R 574093 CDS YP_003875628.1 307066662 9726049 27889..28602 1 NC_014494.1 Operon 13 Gene 1 COG3617 Prophage antirepressor; prophage antirepressor 28602 9726049 SPAP_0032 Streptococcus pneumoniae AP200 prophage antirepressor YP_003875628.1 27889 D 574093 CDS YP_003875629.1 307066663 9726050 28615..28872 1 NC_014494.1 Operon 13 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 28872 9726050 SPAP_0033 Streptococcus pneumoniae AP200 hypothetical protein YP_003875629.1 28615 D 574093 CDS YP_003875630.1 307066664 9726051 28958..29278 1 NC_014494.1 Operon 14 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 29278 9726051 SPAP_0034 Streptococcus pneumoniae AP200 hypothetical protein YP_003875630.1 28958 D 574093 CDS YP_003875631.1 307066665 9726052 29294..29587 1 NC_014494.1 Operon 14 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 29587 9726052 SPAP_0035 Streptococcus pneumoniae AP200 hypothetical protein YP_003875631.1 29294 D 574093 CDS YP_003875632.1 307066666 9726053 29571..30407 1 NC_014494.1 similar to gp19 of Streptococcus mitis phage SM1; hypothetical protein 30407 9726053 SPAP_0036 Streptococcus pneumoniae AP200 hypothetical protein YP_003875632.1 29571 D 574093 CDS YP_003875633.1 307066667 9726054 30395..30553 1 NC_014494.1 Operon 14 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 30553 9726054 SPAP_0037 Streptococcus pneumoniae AP200 hypothetical protein YP_003875633.1 30395 D 574093 CDS YP_003875634.1 307066668 9726055 30547..31317 1 NC_014494.1 Operon 14 Gene 5 COG1484 DNA replication protein; DNA replication protein 31317 9726055 SPAP_0038 Streptococcus pneumoniae AP200 DNA replication protein YP_003875634.1 30547 D 574093 CDS YP_003875635.1 307066669 9726056 31332..31526 1 NC_014494.1 Operon 14 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 31526 9726056 SPAP_0039 Streptococcus pneumoniae AP200 hypothetical protein YP_003875635.1 31332 D 574093 CDS YP_003875636.1 307066670 9726057 31526..31753 1 NC_014494.1 Operon 14 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 31753 9726057 SPAP_0040 Streptococcus pneumoniae AP200 hypothetical protein YP_003875636.1 31526 D 574093 CDS YP_003875637.1 307066671 9726058 31746..31850 1 NC_014494.1 Operon 14 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 31850 9726058 SPAP_0041 Streptococcus pneumoniae AP200 hypothetical protein YP_003875637.1 31746 D 574093 CDS YP_003875638.1 307066672 9726059 31938..32147 1 NC_014494.1 Operon 14 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 32147 9726059 SPAP_0042 Streptococcus pneumoniae AP200 hypothetical protein YP_003875638.1 31938 D 574093 CDS YP_003875639.1 307066673 9726060 32119..32436 1 NC_014494.1 Operon 14 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 32436 9726060 SPAP_0043 Streptococcus pneumoniae AP200 hypothetical protein YP_003875639.1 32119 D 574093 CDS YP_003875640.1 307066674 9726061 32438..33133 1 NC_014494.1 Operon 14 Gene 11 Putative gene predicted by FgenesB; hypothetical protein 33133 9726061 SPAP_0044 Streptococcus pneumoniae AP200 hypothetical protein YP_003875640.1 32438 D 574093 CDS YP_003875641.1 307066675 9726062 33371..33724 1 NC_014494.1 Operon 15 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 33724 9726062 SPAP_0045 Streptococcus pneumoniae AP200 hypothetical protein YP_003875641.1 33371 D 574093 CDS YP_003875642.1 307066676 9726063 33706..34170 1 NC_014494.1 Operon 15 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 34170 9726063 SPAP_0046 Streptococcus pneumoniae AP200 hypothetical protein YP_003875642.1 33706 D 574093 CDS YP_003875643.1 307066677 9726064 34279..34821 1 NC_014494.1 Operon 16 Gene 1 COG0582 Integrase; integrase 34821 9726064 SPAP_0047 Streptococcus pneumoniae AP200 integrase YP_003875643.1 34279 D 574093 CDS YP_003875644.1 307066678 9726065 35027..35254 1 NC_014494.1 hypothetical protein 35254 9726065 SPAP_0048 Streptococcus pneumoniae AP200 hypothetical protein YP_003875644.1 35027 D 574093 CDS YP_003875645.1 307066679 9726066 35251..35568 1 NC_014494.1 similar to SAG1857 prophage LambdaSa2; HNH endonuclease family protein 35568 9726066 SPAP_0049 Streptococcus pneumoniae AP200 HNH endonuclease family protein YP_003875645.1 35251 D 574093 CDS YP_003875646.1 307066680 9726067 35705..36190 1 NC_014494.1 Operon 18 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 36190 9726067 SPAP_0050 Streptococcus pneumoniae AP200 hypothetical protein YP_003875646.1 35705 D 574093 CDS YP_003875647.1 307066681 9726068 36183..37895 1 NC_014494.1 Operon 18 Gene 2 COG4626 Phage terminase-like protein, large subunit; phage terminase-like protein large subunit 37895 9726068 SPAP_0051 Streptococcus pneumoniae AP200 phage terminase-like protein large subunit YP_003875647.1 36183 D 574093 CDS YP_003875648.1 307066682 9726069 37904..39046 1 NC_014494.1 similar to SAG1854 prophage LambdaSa2; hypothetical protein 39046 9726069 SPAP_0052 Streptococcus pneumoniae AP200 hypothetical protein YP_003875648.1 37904 D 574093 CDS YP_003875649.1 307066683 9726070 39093..39635 1 NC_014494.1 Operon 19 Gene 2 COG3740 Phage head maturation protease; phage head maturation protease 39635 9726070 SPAP_0053 Streptococcus pneumoniae AP200 phage head maturation protease YP_003875649.1 39093 D 574093 CDS YP_003875650.1 307066684 9726071 39650..40903 1 NC_014494.1 Operon 19 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 40903 9726071 SPAP_0054 Streptococcus pneumoniae AP200 hypothetical protein YP_003875650.1 39650 D 574093 CDS YP_003875651.1 307066685 9726072 40929..41264 1 NC_014494.1 Operon 19 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 41264 9726072 SPAP_0055 Streptococcus pneumoniae AP200 hypothetical protein YP_003875651.1 40929 D 574093 CDS YP_003875652.1 307066686 9726073 41261..41566 1 NC_014494.1 Operon 19 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 41566 9726073 SPAP_0056 Streptococcus pneumoniae AP200 hypothetical protein YP_003875652.1 41261 D 574093 CDS YP_003875653.1 307066687 9726074 41566..41913 1 NC_014494.1 Operon 19 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 41913 9726074 SPAP_0057 Streptococcus pneumoniae AP200 hypothetical protein YP_003875653.1 41566 D 574093 CDS YP_003875654.1 307066688 9726075 41900..42244 1 NC_014494.1 Operon 19 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 42244 9726075 SPAP_0058 Streptococcus pneumoniae AP200 hypothetical protein YP_003875654.1 41900 D 574093 CDS YP_003875655.1 307066689 9726076 42258..42926 1 NC_014494.1 Operon 19 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 42926 9726076 SPAP_0059 Streptococcus pneumoniae AP200 hypothetical protein YP_003875655.1 42258 D 574093 CDS YP_003875656.1 307066690 9726077 42928..43404 1 NC_014494.1 Operon 19 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 43404 9726077 SPAP_0060 Streptococcus pneumoniae AP200 hypothetical protein YP_003875656.1 42928 D 574093 CDS YP_003875657.1 307066691 9726078 43443..43571 1 NC_014494.1 Operon 19 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 43571 9726078 SPAP_0061 Streptococcus pneumoniae AP200 hypothetical protein YP_003875657.1 43443 D 574093 CDS YP_003875658.1 307066692 9726079 43591..46329 1 NC_014494.1 Operon 19 Gene 11 COG5280 Phage-related minor tail protein; phage-related minor tail protein 46329 9726079 SPAP_0062 Streptococcus pneumoniae AP200 phage-related minor tail protein YP_003875658.1 43591 D 574093 CDS YP_003875659.1 307066693 9726080 46326..47048 1 NC_014494.1 Operon 19 Gene 12 Putative gene predicted by FgenesB; hypothetical protein 47048 9726080 SPAP_0063 Streptococcus pneumoniae AP200 hypothetical protein YP_003875659.1 46326 D 574093 CDS YP_003875660.1 307066694 9726081 47049..56156 1 NC_014494.1 Operon 19 Gene 13 COG4926 Phage-related protein; PblB, putative 56156 9726081 SPAP_0064 Streptococcus pneumoniae AP200 PblB, putative YP_003875660.1 47049 D 574093 CDS YP_003875661.1 307066695 9726082 56250..56453 1 NC_014494.1 Operon 19 Gene 15 Putative gene predicted by FgenesB; hypothetical protein 56453 9726082 SPAP_0065 Streptococcus pneumoniae AP200 hypothetical protein YP_003875661.1 56250 D 574093 CDS YP_003875662.1 307066696 9726083 56456..56806 1 NC_014494.1 Operon 19 Gene 16 Putative gene predicted by FgenesB; hypothetical protein 56806 9726083 SPAP_0066 Streptococcus pneumoniae AP200 hypothetical protein YP_003875662.1 56456 D 574093 CDS YP_003875663.1 307066697 9726084 56816..57232 1 NC_014494.1 Operon 19 Gene 17 Putative gene predicted by FgenesB; hypothetical protein 57232 9726084 SPAP_0067 Streptococcus pneumoniae AP200 hypothetical protein YP_003875663.1 56816 D 574093 CDS YP_003875664.1 307066698 9726085 57236..57568 1 NC_014494.1 Operon 19 Gene 18 Putative gene predicted by FgenesB; hypothetical protein 57568 9726085 SPAP_0068 Streptococcus pneumoniae AP200 hypothetical protein YP_003875664.1 57236 D 574093 CDS YP_003875665.1 307066699 9726086 57572..58528 1 NC_014494.1 Operon 19 Gene 19 COG5263 FOG: autolysin; autolysin 58528 9726086 SPAP_0069 Streptococcus pneumoniae AP200 autolysin YP_003875665.1 57572 D 574093 CDS YP_003875666.1 307066700 9726087 complement(58666..58845) 1 NC_014494.1 Operon 20 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 58845 9726087 SPAP_0070 Streptococcus pneumoniae AP200 hypothetical protein YP_003875666.1 58666 R 574093 CDS YP_003875667.1 307066701 9726088 complement(58987..59142) 1 NC_014494.1 hypothetical protein 59142 9726088 SPAP_0071 Streptococcus pneumoniae AP200 hypothetical protein YP_003875667.1 58987 R 574093 CDS YP_003875668.1 307066702 9726089 59416..59883 1 NC_014494.1 Operon 21 Gene 1 COG0590 Cytosine/adenosine deaminases; cytosine/adenosine deaminase 59883 9726089 SPAP_0072 Streptococcus pneumoniae AP200 cytosine/adenosine deaminase YP_003875668.1 59416 D 574093 CDS YP_003875669.1 307066703 9726090 60069..60512 1 NC_014494.1 Operon 22 Gene 1 COG0756 dUTPase; dUTPase 60512 9726090 SPAP_0073 Streptococcus pneumoniae AP200 dUTPase YP_003875669.1 60069 D 574093 CDS YP_003875670.1 307066704 9726091 60514..61029 1 NC_014494.1 Operon 22 Gene 2 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 61029 9726091 SPAP_0074 Streptococcus pneumoniae AP200 fructose-2,6-bisphosphatase YP_003875670.1 60514 D 574093 CDS YP_003875671.1 307066705 9726092 61142..62404 1 NC_014494.1 Operon 23 Gene 1 COG1066 Predicted ATP-dependent serine protease; putative ATP-dependent serine protease 62404 9726092 SPAP_0075 Streptococcus pneumoniae AP200 putative ATP-dependent serine protease YP_003875671.1 61142 D 574093 CDS YP_003875672.1 307066706 9726093 62408..62974 1 NC_014494.1 Operon 23 Gene 2 COG0288 Carbonic anhydrase; carbonic anhydrase 62974 9726093 SPAP_0076 Streptococcus pneumoniae AP200 carbonic anhydrase YP_003875672.1 62408 D 574093 CDS YP_003875673.1 307066707 9726094 62999..63208 1 NC_014494.1 Operon 23 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 63208 9726094 SPAP_0077 Streptococcus pneumoniae AP200 hypothetical protein YP_003875673.1 62999 D 574093 CDS YP_003875674.1 307066708 9726095 63229..63813 1 NC_014494.1 Operon 23 Gene 4 COG2339 Predicted membrane protein; hypothetical protein 63813 9726095 SPAP_0078 Streptococcus pneumoniae AP200 hypothetical protein YP_003875674.1 63229 D 574093 CDS YP_003875675.1 307066709 9726096 63958..64926 1 NC_014494.1 Operon 24 Gene 1 COG0462 Phosphoribosylpyrophosphate synthetase; phosphoribosylpyrophosphate synthetase 64926 9726096 SPAP_0079 Streptococcus pneumoniae AP200 phosphoribosylpyrophosphate synthetase YP_003875675.1 63958 D 574093 CDS YP_003875676.1 307066710 9726097 complement(64862..65341) 1 NC_014494.1 Operon 25 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein 65341 9726097 SPAP_0080 Streptococcus pneumoniae AP200 transposase-like protein YP_003875676.1 64862 R 574093 CDS YP_003875677.1 307066711 9726098 complement(65467..65700) 1 NC_014494.1 Operon 26 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 65700 9726098 SPAP_0081 Streptococcus pneumoniae AP200 hypothetical protein YP_003875677.1 65467 R 574093 CDS YP_003875678.1 307066712 9726099 complement(66129..66338) 1 NC_014494.1 Operon 26 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 66338 9726099 SPAP_0082 Streptococcus pneumoniae AP200 hypothetical protein YP_003875678.1 66129 R 574093 CDS YP_003875679.1 307066713 9726100 66594..69263 1 NC_014494.1 Operon 27 Gene 1 COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; DNA polymerase I - 3'-5' exonuclease and polymerase domains 69263 9726100 SPAP_0083 Streptococcus pneumoniae AP200 DNA polymerase I - 3'-5' exonuclease and polymerase domains YP_003875679.1 66594 D 574093 CDS YP_003875680.1 307066714 9726101 69348..69785 1 NC_014494.1 Operon 27 Gene 2 COG1832 Predicted CoA-binding protein; putative CoA-binding protein 69785 9726101 SPAP_0084 Streptococcus pneumoniae AP200 putative CoA-binding protein YP_003875680.1 69348 D 574093 CDS YP_003875681.1 307066715 9726102 complement(69968..70978) 1 NC_014494.1 Operon 28 Gene 1 COG2855 Predicted membrane protein; hypothetical protein 70978 9726102 SPAP_0085 Streptococcus pneumoniae AP200 hypothetical protein YP_003875681.1 69968 R 574093 CDS YP_003875682.1 307066716 9726103 71127..72296 1 NC_014494.1 Operon 29 Gene 1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase 72296 9726103 SPAP_0086 Streptococcus pneumoniae AP200 aspartate/tyrosine/aromatic aminotransferase YP_003875682.1 71127 D 574093 CDS YP_003875683.1 307066717 9726104 72293..73063 1 NC_014494.1 Operon 29 Gene 2 COG1381 Recombinational DNA repair protein (RecF pathway); recombinational DNA repair ATPase 73063 9726104 SPAP_0087 Streptococcus pneumoniae AP200 recombinational DNA repair ATPase YP_003875683.1 72293 D 574093 CDS YP_003875684.1 307066718 9726105 73060..74052 1 NC_014494.1 Operon 29 Gene 3 COG0416 Fatty acid/phospholipid biosynthesis enzyme; fatty acid/phospholipid biosynthesis enzyme 74052 9726105 SPAP_0088 Streptococcus pneumoniae AP200 fatty acid/phospholipid biosynthesis enzyme YP_003875684.1 73060 D 574093 CDS YP_003875685.1 307066719 9726106 74058..74291 1 NC_014494.1 Operon 29 Gene 4 COG0236 Acyl carrier protein; acyl carrier protein 74291 9726106 SPAP_0089 Streptococcus pneumoniae AP200 acyl carrier protein YP_003875685.1 74058 D 574093 CDS YP_003875686.1 307066720 9726107 75065..75184 1 NC_014494.1 Operon 30 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 75184 9726107 SPAP_0090 Streptococcus pneumoniae AP200 hypothetical protein YP_003875686.1 75065 D 574093 CDS YP_003875687.1 307066721 9726108 75778..77931 1 NC_014494.1 Operon 31 Gene 1 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter 77931 9726108 SPAP_0091 Streptococcus pneumoniae AP200 bacteriocin/lantibiotic ABC exporter YP_003875687.1 75778 D 574093 CDS YP_003875688.1 307066722 9726109 77944..79293 1 NC_014494.1 Operon 31 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 79293 9726109 SPAP_0092 Streptococcus pneumoniae AP200 hypothetical protein YP_003875688.1 77944 D 574093 CDS YP_003875689.1 307066723 9726110 79463..80170 1 NC_014494.1 Operon 32 Gene 1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase 80170 9726110 SPAP_0093 Streptococcus pneumoniae AP200 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase YP_003875689.1 79463 D 574093 CDS YP_003875690.1 307066724 9726111 80227..83952 1 NC_014494.1 Operon 32 Gene 2 COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein 83952 9726111 SPAP_0094 Streptococcus pneumoniae AP200 phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein YP_003875690.1 80227 D 574093 CDS YP_003875691.1 307066725 9726112 84045..85487 1 NC_014494.1 Operon 32 Gene 3 COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase 85487 9726112 SPAP_0095 Streptococcus pneumoniae AP200 glutamine phosphoribosylpyrophosphate amidotransferase YP_003875691.1 84045 D 574093 CDS YP_003875692.1 307066726 9726113 85524..86546 1 NC_014494.1 Operon 32 Gene 4 protein supported gi|169632702|ref|YP_001706438.1| phosphoribosylaminoimidazole synthetase; hypothetical protein 86546 9726113 SPAP_0096 Streptococcus pneumoniae AP200 hypothetical protein YP_003875692.1 85524 D 574093 CDS YP_003875693.1 307066727 9726114 86543..87088 1 NC_014494.1 Operon 32 Gene 5 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; folate-dependent phosphoribosylglycinamide formyltransferase PurN 87088 9726114 SPAP_0097 Streptococcus pneumoniae AP200 folate-dependent phosphoribosylglycinamide formyltransferase PurN YP_003875693.1 86543 D 574093 CDS YP_003875694.1 307066728 9726115 87172..87681 1 NC_014494.1 Operon 33 Gene 1 COG4767 Glycopeptide antibiotics resistance protein; glycopeptide antibiotics resistance protein 87681 9726115 SPAP_0098 Streptococcus pneumoniae AP200 glycopeptide antibiotics resistance protein YP_003875694.1 87172 D 574093 CDS YP_003875695.1 307066729 9726116 87706..89253 1 NC_014494.1 Operon 33 Gene 2 COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); AICAR transformylase/IMP cyclohydrolase PurH 89253 9726116 SPAP_0099 Streptococcus pneumoniae AP200 AICAR transformylase/IMP cyclohydrolase PurH YP_003875695.1 87706 D 574093 CDS YP_003875696.1 307066730 9726117 89375..90637 1 NC_014494.1 Operon 33 Gene 3 COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine-glycine ligase 90637 9726117 SPAP_0100 Streptococcus pneumoniae AP200 phosphoribosylamine-glycine ligase YP_003875696.1 89375 D 574093 CDS YP_003875697.1 307066731 9726118 complement(90601..90801) 1 NC_014494.1 Operon 34 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 90801 9726118 SPAP_0101 Streptococcus pneumoniae AP200 hypothetical protein YP_003875697.1 90601 R 574093 CDS YP_003875698.1 307066732 9726119 91040..91528 1 NC_014494.1 Operon 35 Gene 1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylcarboxyaminoimidazole mutase 91528 9726119 SPAP_0102 Streptococcus pneumoniae AP200 phosphoribosylcarboxyaminoimidazole mutase YP_003875698.1 91040 D 574093 CDS YP_003875699.1 307066733 9726120 91515..92606 1 NC_014494.1 Operon 35 Gene 2 COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase 92606 9726120 SPAP_0103 Streptococcus pneumoniae AP200 phosphoribosylaminoimidazole carboxylase YP_003875699.1 91515 D 574093 CDS YP_003875700.1 307066734 9726121 92616..92843 1 NC_014494.1 Operon 35 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 92843 9726121 SPAP_0104 Streptococcus pneumoniae AP200 hypothetical protein YP_003875700.1 92616 D 574093 CDS YP_003875701.1 307066735 9726122 92906..94204 1 NC_014494.1 Operon 35 Gene 4 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 94204 9726122 SPAP_0105 Streptococcus pneumoniae AP200 adenylosuccinate lyase YP_003875701.1 92906 D 574093 CDS YP_003875702.1 307066736 9726123 complement(94259..98218) 1 NC_014494.1 Operon 36 Gene 1 protein supported gi|149001861|ref|ZP_01826834.1| 30S ribosomal protein S4; hypothetical protein 98218 9726123 SPAP_0106 Streptococcus pneumoniae AP200 hypothetical protein YP_003875702.1 94259 R 574093 CDS YP_003875703.1 307066737 9726124 complement(98512..99255) 1 NC_014494.1 Operon 37 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 99255 9726124 SPAP_0107 Streptococcus pneumoniae AP200 transcriptional regulator YP_003875703.1 98512 R 574093 CDS YP_003875704.1 307066738 9726125 99576..101363 1 NC_014494.1 Operon 38 Gene 1 COG1874 Beta-galactosidase; beta-galactosidase 101363 9726125 SPAP_0108 Streptococcus pneumoniae AP200 beta-galactosidase YP_003875704.1 99576 D 574093 CDS YP_003875705.1 307066739 9726126 101360..101836 1 NC_014494.1 Operon 38 Gene 2 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 101836 9726126 SPAP_0109 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB YP_003875705.1 101360 D 574093 CDS YP_003875706.1 307066740 9726127 101864..102769 1 NC_014494.1 Operon 38 Gene 3 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 102769 9726127 SPAP_0110 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC YP_003875706.1 101864 D 574093 CDS YP_003875707.1 307066741 9726128 102756..103571 1 NC_014494.1 Operon 38 Gene 4 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 103571 9726128 SPAP_0111 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID YP_003875707.1 102756 D 574093 CDS YP_003875708.1 307066742 9726129 103578..103982 1 NC_014494.1 Operon 38 Gene 5 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA 103982 9726129 SPAP_0112 Streptococcus pneumoniae AP200 PTS system mannose/fructose-specific transporter subunit IIA YP_003875708.1 103578 D 574093 CDS YP_003875709.1 307066743 9726130 104281..105447 1 NC_014494.1 Operon 39 Gene 1 COG2222 Predicted phosphosugar isomerases; putative phosphosugar isomerase 105447 9726130 SPAP_0113 Streptococcus pneumoniae AP200 putative phosphosugar isomerase YP_003875709.1 104281 D 574093 CDS YP_003875710.1 307066744 9726131 105563..106600 1 NC_014494.1 Operon 40 Gene 1 protein supported gi|15900011|ref|NP_344615.1| aldose 1-epimerase; hypothetical protein 106600 9726131 SPAP_0114 Streptococcus pneumoniae AP200 hypothetical protein YP_003875710.1 105563 D 574093 CDS YP_003875711.1 307066745 9726132 106762..107274 1 NC_014494.1 Operon 41 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 107274 9726132 SPAP_0115 Streptococcus pneumoniae AP200 hypothetical protein YP_003875711.1 106762 D 574093 CDS YP_003875712.1 307066746 9726133 107295..107930 1 NC_014494.1 Operon 41 Gene 2 COG5263 FOG: Choline binding protein I; choline binding protein I 107930 9726133 SPAP_0116 Streptococcus pneumoniae AP200 choline binding protein I YP_003875712.1 107295 D 574093 CDS YP_003875713.1 307066747 9726134 108382..113952 1 NC_014494.1 zinc metalloprotease ZmpC; hypothetical protein 113952 9726134 SPAP_0117 Streptococcus pneumoniae AP200 hypothetical protein YP_003875713.1 108382 D 574093 CDS YP_003875714.1 307066748 9726135 114308..115162 1 NC_014494.1 Operon 43 Gene 1 COG2514 Predicted ring-cleavage extradiol dioxygenase; putative ring-cleavage extradiol dioxygenase 115162 9726135 SPAP_0118 Streptococcus pneumoniae AP200 putative ring-cleavage extradiol dioxygenase YP_003875714.1 114308 D 574093 CDS YP_003875715.1 307066749 9726136 115268..115825 1 NC_014494.1 Operon 44 Gene 1 COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase 115825 9726136 SPAP_0119 Streptococcus pneumoniae AP200 acetyltransferase YP_003875715.1 115268 D 574093 CDS YP_003875716.1 307066750 9726137 116042..116806 1 NC_014494.1 Operon 45 Gene 1 COG2820 Uridine phosphorylase; Uridine phosphorylase 116806 9726137 SPAP_0120 Streptococcus pneumoniae AP200 Uridine phosphorylase YP_003875716.1 116042 D 574093 CDS YP_003875717.1 307066751 9726138 117419..118798 1 NC_014494.1 Operon 46 Gene 1 COG0168 Trk-type K+ transport systems, membrane components; Trk-type K+ transport systems membrane protein 118798 9726138 SPAP_0121 Streptococcus pneumoniae AP200 Trk-type K+ transport systems membrane protein YP_003875717.1 117419 D 574093 CDS YP_003875718.1 307066752 9726139 118812..119477 1 NC_014494.1 Operon 46 Gene 2 COG0569 K+ transport systems, NAD-binding component; K+ transport systems NAD-binding component 119477 9726139 SPAP_0122 Streptococcus pneumoniae AP200 K+ transport systems NAD-binding component YP_003875718.1 118812 D 574093 CDS YP_003875719.1 307066753 9726140 119612..119815 1 NC_014494.1 Operon 47 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 119815 9726140 SPAP_0123 Streptococcus pneumoniae AP200 hypothetical protein YP_003875719.1 119612 D 574093 CDS YP_003875720.1 307066754 9726141 119877..120050 1 NC_014494.1 Operon 47 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 120050 9726141 SPAP_0124 Streptococcus pneumoniae AP200 hypothetical protein YP_003875720.1 119877 D 574093 CDS YP_003875721.1 307066755 9726142 120117..120527 1 NC_014494.1 Operon 47 Gene 3 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 120527 9726142 SPAP_0125 Streptococcus pneumoniae AP200 glycosyltransferase YP_003875721.1 120117 D 574093 CDS YP_003875722.1 307066756 9726143 120643..122304 1 NC_014494.1 cell wall surface anchor family protein; hypothetical protein 122304 9726143 SPAP_0126 Streptococcus pneumoniae AP200 hypothetical protein YP_003875722.1 120643 D 574093 CDS YP_003875723.1 307066757 9726144 122471..123169 1 NC_014494.1 Operon 49 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 123169 9726144 SPAP_0127 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003875723.1 122471 D 574093 CDS YP_003875724.1 307066758 9726145 123166..124218 1 NC_014494.1 Operon 49 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 124218 9726145 SPAP_0128 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003875724.1 123166 D 574093 CDS YP_003875725.1 307066759 9726146 124413..125024 1 NC_014494.1 Operon 50 Gene 1 protein supported gi|15900029|ref|NP_344633.1| 30S ribosomal protein S4; hypothetical protein 125024 9726146 SPAP_0129 Streptococcus pneumoniae AP200 hypothetical protein YP_003875725.1 124413 D 574093 CDS YP_003875726.1 307066760 9726147 125209..125367 1 NC_014494.1 transposase-like protein, IS630 125367 9726147 SPAP_0130 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003875726.1 125209 D 574093 CDS YP_003875727.1 307066761 9726148 complement(125465..125605) 1 NC_014494.1 transposase-like protein, ISSpn2 125605 9726148 SPAP_0131 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003875727.1 125465 R 574093 CDS YP_003875728.1 307066762 9726149 125685..125945 1 NC_014494.1 Operon 53 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 125945 9726149 SPAP_0132 Streptococcus pneumoniae AP200 hypothetical protein YP_003875728.1 125685 D 574093 CDS YP_003875729.1 307066763 9726150 125860..126120 1 NC_014494.1 Operon 53 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 126120 9726150 SPAP_0133 Streptococcus pneumoniae AP200 hypothetical protein YP_003875729.1 125860 D 574093 CDS YP_003875730.1 307066764 9726151 126439..127368 1 NC_014494.1 Operon 54 Gene 1 COG4209 ABC-type polysaccharide transport system, permease component; polysaccharide ABC transporter permease 127368 9726151 SPAP_0134 Streptococcus pneumoniae AP200 polysaccharide ABC transporter permease YP_003875730.1 126439 D 574093 CDS YP_003875731.1 307066765 9726152 127382..128305 1 NC_014494.1 Operon 54 Gene 2 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 128305 9726152 SPAP_0135 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003875731.1 127382 D 574093 CDS YP_003875732.1 307066766 9726153 128409..129884 1 NC_014494.1 Operon 54 Gene 3 protein supported gi|15900035|ref|NP_344639.1| ABC transporter, substrate-binding protein; hypothetical protein 129884 9726153 SPAP_0136 Streptococcus pneumoniae AP200 hypothetical protein YP_003875732.1 128409 D 574093 CDS YP_003875733.1 307066767 9726154 130156..131142 1 NC_014494.1 Operon 55 Gene 1 COG1054 Predicted sulfurtransferase; putative sulfurtransferase 131142 9726154 SPAP_0137 Streptococcus pneumoniae AP200 putative sulfurtransferase YP_003875733.1 130156 D 574093 CDS YP_003875734.1 307066768 9726155 131264..132115 1 NC_014494.1 Operon 55 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 132115 9726155 SPAP_0138 Streptococcus pneumoniae AP200 hypothetical protein YP_003875734.1 131264 D 574093 CDS YP_003875735.1 307066769 9726156 complement(132196..133260) 1 NC_014494.1 Operon 56 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 133260 9726156 SPAP_0139 Streptococcus pneumoniae AP200 hypothetical protein YP_003875735.1 132196 R 574093 CDS YP_003875736.1 307066770 9726157 complement(133323..134234) 1 NC_014494.1 Operon 56 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 134234 9726157 SPAP_0140 Streptococcus pneumoniae AP200 hypothetical protein YP_003875736.1 133323 R 574093 CDS YP_003875737.1 307066771 9726158 complement(134227..134820) 1 NC_014494.1 Operon 56 Gene 3 COG4709 Predicted membrane protein; hypothetical protein 134820 9726158 SPAP_0141 Streptococcus pneumoniae AP200 hypothetical protein YP_003875737.1 134227 R 574093 CDS YP_003875738.1 307066772 9726159 complement(134807..135133) 1 NC_014494.1 Operon 56 Gene 4 COG1695 Predicted transcriptional regulators; putative transcriptional regulator 135133 9726159 SPAP_0142 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003875738.1 134807 R 574093 CDS YP_003875739.1 307066773 9726160 complement(135272..136438) 1 NC_014494.1 Operon 57 Gene 1 COG2807 Cyanate permease; cyanate permease 136438 9726160 SPAP_0143 Streptococcus pneumoniae AP200 cyanate permease YP_003875739.1 135272 R 574093 CDS YP_003875740.1 307066774 9726161 136496..137656 1 NC_014494.1 Operon 58 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 137656 9726161 SPAP_0144 Streptococcus pneumoniae AP200 glycosyltransferase YP_003875740.1 136496 D 574093 CDS YP_003875741.1 307066775 9726162 137695..139545 1 NC_014494.1 Operon 58 Gene 2 COG1086 Predicted nucleoside-diphosphate sugar epimerases; putative nucleoside-diphosphate sugar epimerase 139545 9726162 SPAP_0145 Streptococcus pneumoniae AP200 putative nucleoside-diphosphate sugar epimerase YP_003875741.1 137695 D 574093 CDS YP_003875742.1 307066776 9726163 complement(139805..140437) 1 NC_014494.1 Operon 59 Gene 1 COG0546 Predicted phosphatases; putative phosphatase 140437 9726163 SPAP_0146 Streptococcus pneumoniae AP200 putative phosphatase YP_003875742.1 139805 R 574093 CDS YP_003875743.1 307066777 9726164 complement(140459..141331) 1 NC_014494.1 Operon 59 Gene 2 COG1760 L-serine deaminase; L-serine deaminase 141331 9726164 SPAP_0147 Streptococcus pneumoniae AP200 L-serine deaminase YP_003875743.1 140459 R 574093 CDS YP_003875744.1 307066778 9726165 complement(141340..142011) 1 NC_014494.1 Operon 59 Gene 3 COG1760 L-serine deaminase; L-serine deaminase 142011 9726165 SPAP_0148 Streptococcus pneumoniae AP200 L-serine deaminase YP_003875744.1 141340 R 574093 CDS YP_003875745.1 307066779 9726166 142253..142840 1 NC_014494.1 Operon 60 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 142840 9726166 SPAP_0149 Streptococcus pneumoniae AP200 hypothetical protein YP_003875745.1 142253 D 574093 CDS YP_003875746.1 307066780 9726167 complement(142892..143212) 1 NC_014494.1 Operon 61 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 143212 9726167 SPAP_0150 Streptococcus pneumoniae AP200 hypothetical protein YP_003875746.1 142892 R 574093 CDS YP_003875747.1 307066781 9726168 complement(143420..143644) 1 NC_014494.1 Operon 62 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 143644 9726168 SPAP_0151 Streptococcus pneumoniae AP200 hypothetical protein YP_003875747.1 143420 R 574093 CDS YP_003875748.1 307066782 9726169 143643..143930 1 NC_014494.1 Operon 63 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 143930 9726169 SPAP_0152 Streptococcus pneumoniae AP200 hypothetical protein YP_003875748.1 143643 D 574093 CDS YP_003875749.1 307066783 9726170 143982..146090 1 NC_014494.1 Operon 63 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 146090 9726170 SPAP_0153 Streptococcus pneumoniae AP200 hypothetical protein YP_003875749.1 143982 D 574093 CDS YP_003875750.1 307066784 9726171 146087..146728 1 NC_014494.1 Operon 63 Gene 3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 146728 9726171 SPAP_0154 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003875750.1 146087 D 574093 CDS YP_003875751.1 307066785 9726172 146935..147741 1 NC_014494.1 Operon 64 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 147741 9726172 SPAP_0155 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003875751.1 146935 D 574093 CDS YP_003875752.1 307066786 9726173 147758..148954 1 NC_014494.1 Operon 64 Gene 2 COG0137 Argininosuccinate synthase; argininosuccinate synthase 148954 9726173 SPAP_0156 Streptococcus pneumoniae AP200 argininosuccinate synthase YP_003875752.1 147758 D 574093 CDS YP_003875753.1 307066787 9726174 148983..150374 1 NC_014494.1 Operon 64 Gene 3 COG0165 Argininosuccinate lyase; argininosuccinate lyase 150374 9726174 SPAP_0157 Streptococcus pneumoniae AP200 argininosuccinate lyase YP_003875753.1 148983 D 574093 CDS YP_003875754.1 307066788 9726175 complement(150561..151424) 1 NC_014494.1 Operon 65 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 151424 9726175 SPAP_0158 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003875754.1 150561 R 574093 CDS YP_003875755.1 307066789 9726176 151992..152228 1 NC_014494.1 Operon 66 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 152228 9726176 SPAP_0159 Streptococcus pneumoniae AP200 hypothetical protein YP_003875755.1 151992 D 574093 CDS YP_003875756.1 307066790 9726177 152206..152700 1 NC_014494.1 Operon 66 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 152700 9726177 SPAP_0160 Streptococcus pneumoniae AP200 hypothetical protein YP_003875756.1 152206 D 574093 CDS YP_003875757.1 307066791 9726178 152854..153066 1 NC_014494.1 Operon 67 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 153066 9726178 SPAP_0161 Streptococcus pneumoniae AP200 hypothetical protein YP_003875757.1 152854 D 574093 CDS YP_003875758.1 307066792 9726179 153440..153565 1 NC_014494.1 Operon 68 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 153565 9726179 SPAP_0162 Streptococcus pneumoniae AP200 hypothetical protein YP_003875758.1 153440 D 574093 CDS YP_003875759.1 307066793 9726180 153546..153791 1 NC_014494.1 Operon 68 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 153791 9726180 SPAP_0163 Streptococcus pneumoniae AP200 hypothetical protein YP_003875759.1 153546 D 574093 CDS YP_003875760.1 307066794 9726181 153948..155006 1 NC_014494.1 Operon 69 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 155006 9726181 SPAP_0164 Streptococcus pneumoniae AP200 hypothetical protein YP_003875760.1 153948 D 574093 CDS YP_003875761.1 307066795 9726182 155321..156298 1 NC_014494.1 Operon 70 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 156298 9726182 SPAP_0165 Streptococcus pneumoniae AP200 hypothetical protein YP_003875761.1 155321 D 574093 CDS YP_003875762.1 307066796 9726183 156675..157049 1 NC_014494.1 Operon 71 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 157049 9726183 SPAP_0166 Streptococcus pneumoniae AP200 hypothetical protein YP_003875762.1 156675 D 574093 CDS YP_003875763.1 307066797 9726184 157287..158159 1 NC_014494.1 Operon 72 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 158159 9726184 SPAP_0167 Streptococcus pneumoniae AP200 hypothetical protein YP_003875763.1 157287 D 574093 CDS YP_003875764.1 307066798 9726185 158215..158454 1 NC_014494.1 Operon 72 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 158454 9726185 SPAP_0168 Streptococcus pneumoniae AP200 hypothetical protein YP_003875764.1 158215 D 574093 CDS YP_003875765.1 307066799 9726186 158655..159179 1 NC_014494.1 Operon 73 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 159179 9726186 SPAP_0169 Streptococcus pneumoniae AP200 hypothetical protein YP_003875765.1 158655 D 574093 CDS YP_003875766.1 307066800 9726187 159658..159855 1 NC_014494.1 Operon 74 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 159855 9726187 SPAP_0170 Streptococcus pneumoniae AP200 hypothetical protein YP_003875766.1 159658 D 574093 CDS YP_003875767.1 307066801 9726188 160312..160551 1 NC_014494.1 Operon 75 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 160551 9726188 SPAP_0171 Streptococcus pneumoniae AP200 hypothetical protein YP_003875767.1 160312 D 574093 CDS YP_003875768.1 307066802 9726189 160536..160814 1 NC_014494.1 Operon 75 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 160814 9726189 SPAP_0172 Streptococcus pneumoniae AP200 hypothetical protein YP_003875768.1 160536 D 574093 CDS YP_003875769.1 307066803 9726190 161100..163379 1 NC_014494.1 Operon 76 Gene 1 COG5263 FOG: surface protein pspA precursor; surface protein pspA precursor 163379 9726190 SPAP_0173 Streptococcus pneumoniae AP200 surface protein pspA precursor YP_003875769.1 161100 D 574093 CDS YP_003875770.1 307066804 9726191 163780..164901 1 NC_014494.1 Operon 77 Gene 1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 164901 9726191 SPAP_0174 Streptococcus pneumoniae AP200 putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase YP_003875770.1 163780 D 574093 CDS YP_003875771.1 307066805 9726192 165042..165497 1 NC_014494.1 Operon 78 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 165497 9726192 SPAP_0175 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003875771.1 165042 D 574093 CDS YP_003875772.1 307066806 9726193 165507..167420 1 NC_014494.1 Operon 78 Gene 2 COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; NAD/FAD-utilizing enzyme apparently involved in cell division 167420 9726193 SPAP_0176 Streptococcus pneumoniae AP200 NAD/FAD-utilizing enzyme apparently involved in cell division YP_003875772.1 165507 D 574093 CDS YP_003875773.1 307066807 9726194 complement(167615..169294) 1 NC_014494.1 Operon 79 Gene 1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; putative metallo-beta-lactamase superfamily hydrolase 169294 9726194 SPAP_0177 Streptococcus pneumoniae AP200 putative metallo-beta-lactamase superfamily hydrolase YP_003875773.1 167615 R 574093 CDS YP_003875774.1 307066808 9726195 complement(169296..169529) 1 NC_014494.1 Operon 79 Gene 2 COG5503 Uncharacterized conserved small protein; hypothetical protein 169529 9726195 SPAP_0178 Streptococcus pneumoniae AP200 hypothetical protein YP_003875774.1 169296 R 574093 CDS YP_003875775.1 307066809 9726196 169809..170132 1 NC_014494.1 Operon 80 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 170132 9726196 SPAP_0179 Streptococcus pneumoniae AP200 hypothetical protein YP_003875775.1 169809 D 574093 CDS YP_003875776.1 307066810 9726197 complement(170154..170351) 1 NC_014494.1 Operon 81 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 170351 9726197 SPAP_0180 Streptococcus pneumoniae AP200 hypothetical protein YP_003875776.1 170154 R 574093 CDS YP_003875777.1 307066811 9726198 complement(170345..170497) 1 NC_014494.1 Operon 81 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 170497 9726198 SPAP_0181 Streptococcus pneumoniae AP200 hypothetical protein YP_003875777.1 170345 R 574093 CDS YP_003875778.1 307066812 9726199 complement(170499..170684) 1 NC_014494.1 Operon 81 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 170684 9726199 SPAP_0182 Streptococcus pneumoniae AP200 hypothetical protein YP_003875778.1 170499 R 574093 CDS YP_003875779.1 307066813 9726200 170862..171545 1 NC_014494.1 Operon 82 Gene 1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; inactive metal-dependent protease-like protein 171545 9726200 SPAP_0183 Streptococcus pneumoniae AP200 inactive metal-dependent protease-like protein YP_003875779.1 170862 D 574093 CDS YP_003875780.1 307066814 9726201 171542..171979 1 NC_014494.1 Operon 82 Gene 2 protein supported gi|15902174|ref|NP_357724.1| ribosomal protein alanine acetyltransferase; hypothetical protein 171979 9726201 SPAP_0184 Streptococcus pneumoniae AP200 hypothetical protein YP_003875780.1 171542 D 574093 CDS YP_003875781.1 307066815 9726202 171969..172979 1 NC_014494.1 Operon 82 Gene 3 protein supported gi|229232313|ref|ZP_04356740.1| (SSU ribosomal protein S18P)-alanine acetyltransferase; hypothetical protein 172979 9726202 SPAP_0185 Streptococcus pneumoniae AP200 hypothetical protein YP_003875781.1 171969 D 574093 CDS YP_003875782.1 307066816 9726203 complement(173019..173405) 1 NC_014494.1 Operon 83 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 173405 9726203 SPAP_0186 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003875782.1 173019 R 574093 CDS YP_003875783.1 307066817 9726204 complement(173396..174013) 1 NC_014494.1 Operon 83 Gene 2 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 174013 9726204 SPAP_0187 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003875783.1 173396 R 574093 CDS YP_003875784.1 307066818 9726205 complement(175031..175234) 1 NC_014494.1 Operon 84 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 175234 9726205 SPAP_0188 Streptococcus pneumoniae AP200 hypothetical protein YP_003875784.1 175031 R 574093 CDS YP_003875785.1 307066819 9726206 175756..176331 1 NC_014494.1 Operon 85 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 176331 9726206 SPAP_0190 Streptococcus pneumoniae AP200 hypothetical protein YP_003875785.1 175756 D 574093 CDS YP_003875786.1 307066820 9726207 176514..176798 1 NC_014494.1 Operon 86 Gene 1 COG0438 Glycosyltransferase; glycosyltransferase 176798 9726207 SPAP_0191 Streptococcus pneumoniae AP200 glycosyltransferase YP_003875786.1 176514 D 574093 CDS YP_003875787.1 307066821 9726208 176791..177744 1 NC_014494.1 Operon 86 Gene 2 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 177744 9726208 SPAP_0192 Streptococcus pneumoniae AP200 glycosyltransferase YP_003875787.1 176791 D 574093 CDS YP_003875788.1 307066822 9726209 177754..179370 1 NC_014494.1 Operon 86 Gene 3 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 179370 9726209 SPAP_0193 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003875788.1 177754 D 574093 CDS YP_003875789.1 307066823 9726210 179390..179977 1 NC_014494.1 Operon 86 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 179977 9726210 SPAP_0194 Streptococcus pneumoniae AP200 hypothetical protein YP_003875789.1 179390 D 574093 CDS YP_003875790.1 307066824 9726211 180007..180144 1 NC_014494.1 Operon 86 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 180144 9726211 SPAP_0195 Streptococcus pneumoniae AP200 hypothetical protein YP_003875790.1 180007 D 574093 CDS YP_003875791.1 307066825 9726212 180173..180499 1 NC_014494.1 Operon 86 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 180499 9726212 SPAP_0196 Streptococcus pneumoniae AP200 hypothetical protein YP_003875791.1 180173 D 574093 CDS YP_003875792.1 307066826 9726213 180519..180635 1 NC_014494.1 Operon 86 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 180635 9726213 SPAP_0197 Streptococcus pneumoniae AP200 hypothetical protein YP_003875792.1 180519 D 574093 CDS YP_003875793.1 307066827 9726214 180738..180965 1 NC_014494.1 Operon 87 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 180965 9726214 SPAP_0198 Streptococcus pneumoniae AP200 hypothetical protein YP_003875793.1 180738 D 574093 CDS YP_003875794.1 307066828 9726215 complement(180962..181339) 1 NC_014494.1 Operon 88 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 181339 9726215 SPAP_0199 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003875794.1 180962 R 574093 CDS YP_003875795.1 307066829 9726216 complement(181351..181776) 1 NC_014494.1 transposase-like protein, IS1515 181776 9726216 SPAP_0200 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003875795.1 181351 R 574093 CDS YP_003875796.1 307066830 9726217 182157..182585 1 NC_014494.1 Operon 89 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 182585 9726217 SPAP_0201 Streptococcus pneumoniae AP200 hypothetical protein YP_003875796.1 182157 D 574093 CDS YP_003875797.1 307066831 9726218 182597..183346 1 NC_014494.1 Operon 89 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 183346 9726218 SPAP_0202 Streptococcus pneumoniae AP200 hypothetical protein YP_003875797.1 182597 D 574093 CDS YP_003875798.1 307066832 9726219 183359..183496 1 NC_014494.1 Operon 89 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 183496 9726219 SPAP_0203 Streptococcus pneumoniae AP200 hypothetical protein YP_003875798.1 183359 D 574093 CDS YP_003875799.1 307066833 9726220 183510..184532 1 NC_014494.1 Operon 89 Gene 4 COG1004 Predicted UDP-glucose 6-dehydrogenase; putative UDP-glucose 6-dehydrogenase 184532 9726220 SPAP_0204 Streptococcus pneumoniae AP200 putative UDP-glucose 6-dehydrogenase YP_003875799.1 183510 D 574093 CDS YP_003875800.1 307066834 9726221 184927..185790 1 NC_014494.1 Operon 90 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 185790 9726221 SPAP_0205 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003875800.1 184927 D 574093 CDS YP_003875801.1 307066835 9726222 186076..186309 1 NC_014494.1 Operon 91 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 186309 9726222 SPAP_0206 Streptococcus pneumoniae AP200 hypothetical protein YP_003875801.1 186076 D 574093 CDS YP_003875802.1 307066836 9726223 186331..187008 1 NC_014494.1 Operon 91 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 187008 9726223 SPAP_0207 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003875802.1 186331 D 574093 CDS YP_003875803.1 307066837 9726224 187020..187685 1 NC_014494.1 Operon 91 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 187685 9726224 SPAP_0208 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003875803.1 187020 D 574093 CDS YP_003875804.1 307066838 9726225 187757..188983 1 NC_014494.1 Operon 91 Gene 4 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 188983 9726225 SPAP_0209 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003875804.1 187757 D 574093 CDS YP_003875805.1 307066839 9726226 complement(189218..189412) 1 NC_014494.1 Operon 92 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 189412 9726226 SPAP_0210 Streptococcus pneumoniae AP200 hypothetical protein YP_003875805.1 189218 R 574093 CDS YP_003875806.1 307066840 9726227 189483..190139 1 NC_014494.1 Operon 93 Gene 1 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); putative branched-chain amino acid permease 190139 9726227 SPAP_0211 Streptococcus pneumoniae AP200 putative branched-chain amino acid permease YP_003875806.1 189483 D 574093 CDS YP_003875807.1 307066841 9726228 190129..190452 1 NC_014494.1 Operon 93 Gene 2 COG4392 Predicted membrane protein; hypothetical protein 190452 9726228 SPAP_0212 Streptococcus pneumoniae AP200 hypothetical protein YP_003875807.1 190129 D 574093 CDS YP_003875808.1 307066842 9726229 190555..191385 1 NC_014494.1 Operon 94 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 191385 9726229 SPAP_0213 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003875808.1 190555 D 574093 CDS YP_003875809.1 307066843 9726230 191539..192393 1 NC_014494.1 Operon 95 Gene 1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; metal ion ABC transporter periplasmic protein/surface antigen 192393 9726230 SPAP_0214 Streptococcus pneumoniae AP200 metal ion ABC transporter periplasmic protein/surface antigen YP_003875809.1 191539 D 574093 CDS YP_003875810.1 307066844 9726231 192493..193866 1 NC_014494.1 Operon 95 Gene 2 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 193866 9726231 SPAP_0215 Streptococcus pneumoniae AP200 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases YP_003875810.1 192493 D 574093 CDS YP_003875811.1 307066845 9726232 193859..194920 1 NC_014494.1 Operon 95 Gene 3 COG1135 ABC-type metal ion transport system, ATPase component; metal ion ABC transporter ATPase 194920 9726232 SPAP_0216 Streptococcus pneumoniae AP200 metal ion ABC transporter ATPase YP_003875811.1 193859 D 574093 CDS YP_003875812.1 307066846 9726233 194922..195614 1 NC_014494.1 Operon 95 Gene 4 COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter permease 195614 9726233 SPAP_0217 Streptococcus pneumoniae AP200 metal ion ABC transporter permease YP_003875812.1 194922 D 574093 CDS YP_003875813.1 307066847 9726234 complement(195644..196213) 1 NC_014494.1 Operon 96 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 196213 9726234 SPAP_0218 Streptococcus pneumoniae AP200 hypothetical protein YP_003875813.1 195644 R 574093 CDS YP_003875814.1 307066848 9726235 196348..196962 1 NC_014494.1 Operon 97 Gene 1 COG5578 Predicted integral membrane protein; putative integral membrane protein 196962 9726235 SPAP_0219 Streptococcus pneumoniae AP200 putative integral membrane protein YP_003875814.1 196348 D 574093 CDS YP_003875815.1 307066849 9726236 197012..198610 1 NC_014494.1 Operon 97 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 198610 9726236 SPAP_0220 Streptococcus pneumoniae AP200 putative signal transduction protein YP_003875815.1 197012 D 574093 CDS YP_003875816.1 307066850 9726237 198622..199908 1 NC_014494.1 Operon 97 Gene 3 COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; CheY-like receiver/AraC DNA-binding domain-containing response regulator 199908 9726237 SPAP_0221 Streptococcus pneumoniae AP200 CheY-like receiver/AraC DNA-binding domain-containing response regulator YP_003875816.1 198622 D 574093 CDS YP_003875817.1 307066851 9726238 199960..200493 1 NC_014494.1 Operon 97 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 200493 9726238 SPAP_0222 Streptococcus pneumoniae AP200 hypothetical protein YP_003875817.1 199960 D 574093 CDS YP_003875818.1 307066852 9726239 200559..201041 1 NC_014494.1 Operon 98 Gene 1 COG1780 Protein involved in ribonucleotide reduction; ribonucleotide reduction protein 201041 9726239 SPAP_0223 Streptococcus pneumoniae AP200 ribonucleotide reduction protein YP_003875818.1 200559 D 574093 CDS YP_003875819.1 307066853 9726240 complement(201334..202596) 1 NC_014494.1 Operon 99 Gene 1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; Mn2+ and Fe2+ transporters of the NRAMP family 202596 9726240 SPAP_0224 Streptococcus pneumoniae AP200 Mn2+ and Fe2+ transporters of the NRAMP family YP_003875819.1 201334 R 574093 CDS YP_003875820.1 307066854 9726241 complement(202906..203364) 1 NC_014494.1 Operon 100 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 203364 9726241 SPAP_0225 Streptococcus pneumoniae AP200 hypothetical protein YP_003875820.1 202906 R 574093 CDS YP_003875821.1 307066855 9726242 complement(203361..203801) 1 NC_014494.1 Operon 100 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 203801 9726242 SPAP_0226 Streptococcus pneumoniae AP200 LytR/AlgR family response regulator YP_003875821.1 203361 R 574093 CDS YP_003875822.1 307066856 9726243 204157..206106 1 NC_014494.1 Operon 101 Gene 1 COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein 206106 9726243 SPAP_0227 Streptococcus pneumoniae AP200 DNA mismatch repair protein YP_003875822.1 204157 D 574093 CDS YP_003875823.1 307066857 9726244 complement(206431..206898) 1 NC_014494.1 Operon 102 Gene 1 COG0054 Riboflavin synthase beta-chain; riboflavin synthase beta-chain 206898 9726244 SPAP_0228 Streptococcus pneumoniae AP200 riboflavin synthase beta-chain YP_003875823.1 206431 R 574093 CDS YP_003875824.1 307066858 9726245 complement(206899..208104) 1 NC_014494.1 Operon 102 Gene 2 COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase 208104 9726245 SPAP_0229 Streptococcus pneumoniae AP200 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_003875824.1 206899 R 574093 CDS YP_003875825.1 307066859 9726246 complement(208124..208759) 1 NC_014494.1 Operon 102 Gene 3 COG0307 Riboflavin synthase alpha chain; riboflavin synthase alpha chain 208759 9726246 SPAP_0230 Streptococcus pneumoniae AP200 riboflavin synthase alpha chain YP_003875825.1 208124 R 574093 CDS YP_003875826.1 307066860 9726247 complement(208744..209844) 1 NC_014494.1 Operon 102 Gene 4 COG1985 Pyrimidine reductase, riboflavin biosynthesis; pyrimidine reductase, riboflavin biosynthesis 209844 9726247 SPAP_0231 Streptococcus pneumoniae AP200 pyrimidine reductase, riboflavin biosynthesis YP_003875826.1 208744 R 574093 CDS YP_003875827.1 307066861 9726248 209935..210144 1 NC_014494.1 Operon 103 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 210144 9726248 SPAP_0232 Streptococcus pneumoniae AP200 hypothetical protein YP_003875827.1 209935 D 574093 CDS YP_003875828.1 307066862 9726249 210250..210843 1 NC_014494.1 Operon 104 Gene 1 COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction resolvasome DNA-binding subunit 210843 9726249 SPAP_0233 Streptococcus pneumoniae AP200 Holliday junction resolvasome DNA-binding subunit YP_003875828.1 210250 D 574093 CDS YP_003875829.1 307066863 9726250 210853..211416 1 NC_014494.1 Operon 104 Gene 2 COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase 211416 9726250 SPAP_0234 Streptococcus pneumoniae AP200 3-methyladenine DNA glycosylase YP_003875829.1 210853 D 574093 CDS YP_003875830.1 307066864 9726251 211416..212090 1 NC_014494.1 Operon 104 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 212090 9726251 SPAP_0235 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003875830.1 211416 D 574093 CDS YP_003875831.1 307066865 9726252 complement(212245..213276) 1 NC_014494.1 Operon 105 Gene 1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; hypothetical protein 213276 9726252 SPAP_0236 Streptococcus pneumoniae AP200 hypothetical protein YP_003875831.1 212245 R 574093 CDS YP_003875832.1 307066866 9726253 complement(213531..214214) 1 NC_014494.1 Operon 106 Gene 1 COG4858 Uncharacterized membrane-bound protein conserved in bacteria; hypothetical protein 214214 9726253 SPAP_0237 Streptococcus pneumoniae AP200 hypothetical protein YP_003875832.1 213531 R 574093 CDS YP_003875833.1 307066867 9726254 complement(214226..215170) 1 NC_014494.1 Operon 106 Gene 2 COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter 215170 9726254 SPAP_0238 Streptococcus pneumoniae AP200 Mg2+ and Co2+ transporter YP_003875833.1 214226 R 574093 CDS YP_003875834.1 307066868 9726255 215302..218133 1 NC_014494.1 Operon 107 Gene 1 COG0178 Excinuclease ATPase subunit; excinuclease ATPase subunit 218133 9726255 SPAP_0239 Streptococcus pneumoniae AP200 excinuclease ATPase subunit YP_003875834.1 215302 D 574093 CDS YP_003875835.1 307066869 9726256 218126..219187 1 NC_014494.1 Operon 107 Gene 2 COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 219187 9726256 SPAP_0240 Streptococcus pneumoniae AP200 Xaa-Pro aminopeptidase YP_003875835.1 218126 D 574093 CDS YP_003875836.1 307066870 9726257 219319..219717 1 NC_014494.1 Operon 108 Gene 1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 219717 9726257 SPAP_0241 Streptococcus pneumoniae AP200 arsenate reductase-like glutaredoxin family protein YP_003875836.1 219319 D 574093 CDS YP_003875837.1 307066871 9726258 219783..220352 1 NC_014494.1 Operon 108 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 220352 9726258 SPAP_0242 Streptococcus pneumoniae AP200 hypothetical protein YP_003875837.1 219783 D 574093 CDS YP_003875838.1 307066872 9726259 220439..220705 1 NC_014494.1 Operon 109 Gene 1 COG4472 Uncharacterized protein conserved in bacteria; hypothetical protein 220705 9726259 SPAP_0243 Streptococcus pneumoniae AP200 hypothetical protein YP_003875838.1 220439 D 574093 CDS YP_003875839.1 307066873 9726260 220709..221128 1 NC_014494.1 Operon 109 Gene 2 COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); putative endonuclease 221128 9726260 SPAP_0244 Streptococcus pneumoniae AP200 putative endonuclease YP_003875839.1 220709 D 574093 CDS YP_003875840.1 307066874 9726261 221144..221449 1 NC_014494.1 Operon 109 Gene 3 COG3906 Uncharacterized protein conserved in bacteria; hypothetical protein 221449 9726261 SPAP_0245 Streptococcus pneumoniae AP200 hypothetical protein YP_003875840.1 221144 D 574093 CDS YP_003875841.1 307066875 9726262 221707..222957 1 NC_014494.1 Operon 110 Gene 1 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 222957 9726262 SPAP_0246 Streptococcus pneumoniae AP200 folylpolyglutamate synthase YP_003875841.1 221707 D 574093 CDS YP_003875842.1 307066876 9726263 223041..223499 1 NC_014494.1 Operon 110 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 223499 9726263 SPAP_0247 Streptococcus pneumoniae AP200 hypothetical protein YP_003875842.1 223041 D 574093 CDS YP_003875843.1 307066877 9726264 223672..225177 1 NC_014494.1 Operon 111 Gene 1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes; phosphatidylserine/ phosphatidylglycerophosphate/cardioli pin synthases-like enzyme 225177 9726264 SPAP_0248 Streptococcus pneumoniae AP200 phosphatidylserine/ phosphatidylglycerophosphate/cardioli pin synthases-like enzyme YP_003875843.1 223672 D 574093 CDS YP_003875844.1 307066878 9726265 225255..225398 1 NC_014494.1 Operon 111 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 225398 9726265 SPAP_0249 Streptococcus pneumoniae AP200 hypothetical protein YP_003875844.1 225255 D 574093 CDS YP_003875845.1 307066879 9726266 225435..226973 1 NC_014494.1 Operon 111 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 226973 9726266 SPAP_0250 Streptococcus pneumoniae AP200 hypothetical protein YP_003875845.1 225435 D 574093 CDS YP_003875846.1 307066880 9726267 227093..229300 1 NC_014494.1 Operon 112 Gene 1 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; oxygen-sensitive ribonucleoside-triphosphate reductase 229300 9726267 SPAP_0251 Streptococcus pneumoniae AP200 oxygen-sensitive ribonucleoside-triphosphate reductase YP_003875846.1 227093 D 574093 CDS YP_003875847.1 307066881 9726268 229312..229452 1 NC_014494.1 Operon 112 Gene 2 protein supported gi|15900139|ref|NP_344743.1| hypothetical protein SP_0203; hypothetical protein 229452 9726268 SPAP_0252 Streptococcus pneumoniae AP200 hypothetical protein YP_003875847.1 229312 D 574093 CDS YP_003875848.1 307066882 9726269 229496..230002 1 NC_014494.1 Operon 112 Gene 3 COG3981 Predicted acetyltransferase; putative acetyltransferase 230002 9726269 SPAP_0253 Streptococcus pneumoniae AP200 putative acetyltransferase YP_003875848.1 229496 D 574093 CDS YP_003875849.1 307066883 9726270 229995..230585 1 NC_014494.1 Operon 112 Gene 4 COG0602 Organic radical activating enzymes; organic radical activating enzyme 230585 9726270 SPAP_0254 Streptococcus pneumoniae AP200 organic radical activating enzyme YP_003875849.1 229995 D 574093 CDS YP_003875850.1 307066884 9726271 230582..231166 1 NC_014494.1 Operon 112 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 231166 9726271 SPAP_0255 Streptococcus pneumoniae AP200 hypothetical protein YP_003875850.1 230582 D 574093 CDS YP_003875851.1 307066885 9726272 231466..231774 1 NC_014494.1 Operon 113 Gene 1 protein supported gi|15900144|ref|NP_344748.1| 30S ribosomal protein S10; hypothetical protein 231774 9726272 SPAP_0256 Streptococcus pneumoniae AP200 hypothetical protein YP_003875851.1 231466 D 574093 CDS YP_003875852.1 307066886 9726273 231991..232617 1 NC_014494.1 Operon 113 Gene 2 protein supported gi|15900145|ref|NP_344749.1| 50S ribosomal protein L3; 50S ribosomal protein L3 232617 9726273 SPAP_0257 Streptococcus pneumoniae AP200 50S ribosomal protein L3 YP_003875852.1 231991 D 574093 CDS YP_003875853.1 307066887 9726274 232642..233265 1 NC_014494.1 Operon 113 Gene 3 protein supported gi|15900146|ref|NP_344750.1| 50S ribosomal protein L4; hypothetical protein 233265 9726274 SPAP_0258 Streptococcus pneumoniae AP200 hypothetical protein YP_003875853.1 232642 D 574093 CDS YP_003875854.1 307066888 9726275 233265..233561 1 NC_014494.1 Operon 113 Gene 4 protein supported gi|15900147|ref|NP_344751.1| 50S ribosomal protein L23; hypothetical protein 233561 9726275 SPAP_0259 Streptococcus pneumoniae AP200 hypothetical protein YP_003875854.1 233265 D 574093 CDS YP_003875855.1 307066889 9726276 233579..234412 1 NC_014494.1 Operon 113 Gene 5 protein supported gi|15900148|ref|NP_344752.1| 50S ribosomal protein L2; hypothetical protein 234412 9726276 SPAP_0260 Streptococcus pneumoniae AP200 hypothetical protein YP_003875855.1 233579 D 574093 CDS YP_003875856.1 307066890 9726277 234516..234797 1 NC_014494.1 Operon 113 Gene 6 protein supported gi|15900149|ref|NP_344753.1| 30S ribosomal protein S19; hypothetical protein 234797 9726277 SPAP_0261 Streptococcus pneumoniae AP200 hypothetical protein YP_003875856.1 234516 D 574093 CDS YP_003875857.1 307066891 9726278 complement(234658..235113) 1 NC_014494.1 Operon 114 Gene 1 protein supported gi|15902237|ref|NP_357787.1| hypothetical protein spr0193; hypothetical protein 235113 9726278 SPAP_0262 Streptococcus pneumoniae AP200 hypothetical protein YP_003875857.1 234658 R 574093 CDS YP_003875858.1 307066892 9726279 234809..235153 1 NC_014494.1 Operon 115 Gene 1 COG0091 Ribosomal protein L22; 50S ribosomal protein L22 235153 9726279 SPAP_0263 Streptococcus pneumoniae AP200 50S ribosomal protein L22 YP_003875858.1 234809 D 574093 CDS YP_003875859.1 307066893 9726280 235166..235819 1 NC_014494.1 Operon 115 Gene 2 protein supported gi|15900151|ref|NP_344755.1| 30S ribosomal protein S3; 30S ribosomal protein S3 235819 9726280 SPAP_0264 Streptococcus pneumoniae AP200 30S ribosomal protein S3 YP_003875859.1 235166 D 574093 CDS YP_003875860.1 307066894 9726281 235823..236236 1 NC_014494.1 Operon 115 Gene 3 protein supported gi|15900152|ref|NP_344756.1| 50S ribosomal protein L16; 50S ribosomal protein L16 236236 9726281 SPAP_0265 Streptococcus pneumoniae AP200 50S ribosomal protein L16 YP_003875860.1 235823 D 574093 CDS YP_003875861.1 307066895 9726282 236246..236452 1 NC_014494.1 Operon 115 Gene 4 protein supported gi|15900153|ref|NP_344757.1| 50S ribosomal protein L29; hypothetical protein 236452 9726282 SPAP_0266 Streptococcus pneumoniae AP200 hypothetical protein YP_003875861.1 236246 D 574093 CDS YP_003875862.1 307066896 9726283 236477..236737 1 NC_014494.1 Operon 115 Gene 5 protein supported gi|15900154|ref|NP_344758.1| 30S ribosomal protein S17; 30S ribosomal protein S17 236737 9726283 SPAP_0267 Streptococcus pneumoniae AP200 30S ribosomal protein S17 YP_003875862.1 236477 D 574093 CDS YP_003875863.1 307066897 9726284 236763..237131 1 NC_014494.1 Operon 115 Gene 6 protein supported gi|15900155|ref|NP_344759.1| 50S ribosomal protein L14; 50S ribosomal protein L14 237131 9726284 SPAP_0268 Streptococcus pneumoniae AP200 50S ribosomal protein L14 YP_003875863.1 236763 D 574093 CDS YP_003875864.1 307066898 9726285 237209..237514 1 NC_014494.1 Operon 115 Gene 7 protein supported gi|15900156|ref|NP_344760.1| 50S ribosomal protein L24; hypothetical protein 237514 9726285 SPAP_0269 Streptococcus pneumoniae AP200 hypothetical protein YP_003875864.1 237209 D 574093 CDS YP_003875865.1 307066899 9726286 237538..238080 1 NC_014494.1 Operon 115 Gene 8 protein supported gi|15900157|ref|NP_344761.1| 50S ribosomal protein L5; 50S ribosomal protein L5 238080 9726286 SPAP_0270 Streptococcus pneumoniae AP200 50S ribosomal protein L5 YP_003875865.1 237538 D 574093 CDS YP_003875866.1 307066900 9726287 238098..238367 1 NC_014494.1 Operon 115 Gene 9 protein supported gi|15900158|ref|NP_344762.1| 30S ribosomal protein S14; hypothetical protein 238367 9726287 SPAP_0271 Streptococcus pneumoniae AP200 hypothetical protein YP_003875866.1 238098 D 574093 CDS YP_003875867.1 307066901 9726288 238653..239051 1 NC_014494.1 Operon 115 Gene 10 protein supported gi|15900160|ref|NP_344764.1| 30S ribosomal protein S8; 30S ribosomal protein S8 239051 9726288 SPAP_0272 Streptococcus pneumoniae AP200 30S ribosomal protein S8 YP_003875867.1 238653 D 574093 CDS YP_003875868.1 307066902 9726289 239243..239779 1 NC_014494.1 Operon 115 Gene 11 protein supported gi|148996647|ref|ZP_01824365.1| 50S ribosomal protein L6; 50S ribosomal protein L6 239779 9726289 SPAP_0273 Streptococcus pneumoniae AP200 50S ribosomal protein L6 YP_003875868.1 239243 D 574093 CDS YP_003875869.1 307066903 9726290 239824..240219 1 NC_014494.1 Operon 115 Gene 12 protein supported gi|182683204|ref|YP_001834951.1| 50S ribosomal protein L18; 50S ribosomal protein L18 240219 9726290 SPAP_0274 Streptococcus pneumoniae AP200 50S ribosomal protein L18 YP_003875869.1 239824 D 574093 CDS YP_003875870.1 307066904 9726291 240237..240731 1 NC_014494.1 Operon 115 Gene 13 protein supported gi|15900163|ref|NP_344767.1| 30S ribosomal protein S5; 30S ribosomal protein S5 240731 9726291 SPAP_0275 Streptococcus pneumoniae AP200 30S ribosomal protein S5 YP_003875870.1 240237 D 574093 CDS YP_003875871.1 307066905 9726292 240703..240927 1 NC_014494.1 Operon 115 Gene 14 protein supported gi|182683206|ref|YP_001834953.1| 50S ribosomal protein L30; hypothetical protein 240927 9726292 SPAP_0276 Streptococcus pneumoniae AP200 hypothetical protein YP_003875871.1 240703 D 574093 CDS YP_003875872.1 307066906 9726293 241072..241512 1 NC_014494.1 Operon 115 Gene 15 protein supported gi|15900165|ref|NP_344769.1| 50S ribosomal protein L15; 50S ribosomal protein L15 241512 9726293 SPAP_0277 Streptococcus pneumoniae AP200 50S ribosomal protein L15 YP_003875872.1 241072 D 574093 CDS YP_003875873.1 307066907 9726294 241525..242835 1 NC_014494.1 Operon 115 Gene 16 COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 242835 9726294 SPAP_0278 Streptococcus pneumoniae AP200 preprotein translocase subunit SecY YP_003875873.1 241525 D 574093 CDS YP_003875874.1 307066908 9726295 242986..243624 1 NC_014494.1 Operon 115 Gene 17 COG0563 Adenylate kinase and related kinases; adenylate kinase-like kinase 243624 9726295 SPAP_0279 Streptococcus pneumoniae AP200 adenylate kinase-like kinase YP_003875874.1 242986 D 574093 CDS YP_003875875.1 307066909 9726296 243741..243959 1 NC_014494.1 Operon 116 Gene 1 protein supported gi|15900168|ref|NP_344772.1| translation initiation factor IF-1; hypothetical protein 243959 9726296 SPAP_0280 Streptococcus pneumoniae AP200 hypothetical protein YP_003875875.1 243741 D 574093 CDS YP_003875876.1 307066910 9726297 243984..244100 1 NC_014494.1 Operon 116 Gene 2 COG0257 Ribosomal protein L36; ribosomal protein L36 244100 9726297 SPAP_0281 Streptococcus pneumoniae AP200 ribosomal protein L36 YP_003875876.1 243984 D 574093 CDS YP_003875877.1 307066911 9726298 244118..244483 1 NC_014494.1 Operon 116 Gene 3 protein supported gi|15900170|ref|NP_344774.1| 30S ribosomal protein S13; 30S ribosomal protein S13 244483 9726298 SPAP_0282 Streptococcus pneumoniae AP200 30S ribosomal protein S13 YP_003875877.1 244118 D 574093 CDS YP_003875878.1 307066912 9726299 244501..244884 1 NC_014494.1 Operon 116 Gene 4 protein supported gi|15900171|ref|NP_344775.1| 30S ribosomal protein S11; 30S ribosomal protein S11 244884 9726299 SPAP_0283 Streptococcus pneumoniae AP200 30S ribosomal protein S11 YP_003875878.1 244501 D 574093 CDS YP_003875879.1 307066913 9726300 244927..245862 1 NC_014494.1 Operon 116 Gene 5 COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha/40 kD subunit 245862 9726300 SPAP_0284 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase subunit alpha/40 kD subunit YP_003875879.1 244927 D 574093 CDS YP_003875880.1 307066914 9726301 245874..246260 1 NC_014494.1 Operon 116 Gene 6 protein supported gi|15902260|ref|NP_357810.1| 50S ribosomal protein L17; hypothetical protein 246260 9726301 SPAP_0285 Streptococcus pneumoniae AP200 hypothetical protein YP_003875880.1 245874 D 574093 CDS YP_003875881.1 307066915 9726302 246525..246791 1 NC_014494.1 Operon 117 Gene 1 COG3830 ACT domain-containing protein; ACT domain-containing protein 246791 9726302 SPAP_0286 Streptococcus pneumoniae AP200 ACT domain-containing protein YP_003875881.1 246525 D 574093 CDS YP_003875882.1 307066916 9726303 246801..248138 1 NC_014494.1 Operon 117 Gene 2 COG2848 Uncharacterized conserved protein; hypothetical protein 248138 9726303 SPAP_0287 Streptococcus pneumoniae AP200 hypothetical protein YP_003875882.1 246801 D 574093 CDS YP_003875883.1 307066917 9726304 248382..249074 1 NC_014494.1 Operon 118 Gene 1 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 249074 9726304 SPAP_0288 Streptococcus pneumoniae AP200 fructose-2,6-bisphosphatase YP_003875883.1 248382 D 574093 CDS YP_003875884.1 307066918 9726305 complement(249177..250199) 1 NC_014494.1 Operon 119 Gene 1 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease 250199 9726305 SPAP_0289 Streptococcus pneumoniae AP200 Fe3+ ABC transporter permease YP_003875884.1 249177 R 574093 CDS YP_003875885.1 307066919 9726306 complement(250196..250564) 1 NC_014494.1 Operon 119 Gene 2 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease 250564 9726306 SPAP_0290 Streptococcus pneumoniae AP200 Fe3+ ABC transporter permease YP_003875885.1 250196 R 574093 CDS YP_003875886.1 307066920 9726307 complement(250812..251762) 1 NC_014494.1 Operon 119 Gene 3 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase 251762 9726307 SPAP_0291 Streptococcus pneumoniae AP200 spermidine/putrescine ABC transporter ATPase YP_003875886.1 250812 R 574093 CDS YP_003875887.1 307066921 9726308 complement(251915..252931) 1 NC_014494.1 Operon 119 Gene 4 COG1840 ABC-type Fe3+ transport system, periplasmic component; Fe3+ ABC transporter periplasmic protein 252931 9726308 SPAP_0292 Streptococcus pneumoniae AP200 Fe3+ ABC transporter periplasmic protein YP_003875887.1 251915 R 574093 CDS YP_003875888.1 307066922 9726309 complement(253148..253345) 1 NC_014494.1 Operon 120 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 253345 9726309 SPAP_0293 Streptococcus pneumoniae AP200 hypothetical protein YP_003875888.1 253148 R 574093 CDS YP_003875889.1 307066923 9726310 complement(253420..254196) 1 NC_014494.1 Operon 120 Gene 2 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate-formate lyase-activating enzyme 254196 9726310 SPAP_0294 Streptococcus pneumoniae AP200 pyruvate-formate lyase-activating enzyme YP_003875889.1 253420 R 574093 CDS YP_003875890.1 307066924 9726311 254318..255064 1 NC_014494.1 Operon 121 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 255064 9726311 SPAP_0295 Streptococcus pneumoniae AP200 sugar metabolism transcriptional regulator YP_003875890.1 254318 D 574093 CDS YP_003875891.1 307066925 9726312 255077..256057 1 NC_014494.1 Operon 121 Gene 2 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator 256057 9726312 SPAP_0296 Streptococcus pneumoniae AP200 transcriptional regulator YP_003875891.1 255077 D 574093 CDS YP_003875892.1 307066926 9726313 256252..256572 1 NC_014494.1 Operon 122 Gene 1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 256572 9726313 SPAP_0297 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIA YP_003875892.1 256252 D 574093 CDS YP_003875893.1 307066927 9726314 256618..256926 1 NC_014494.1 Operon 122 Gene 2 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 256926 9726314 SPAP_0298 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIB YP_003875893.1 256618 D 574093 CDS YP_003875894.1 307066928 9726315 256943..258241 1 NC_014494.1 Operon 122 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 258241 9726315 SPAP_0299 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003875894.1 256943 D 574093 CDS YP_003875895.1 307066929 9726316 258392..260830 1 NC_014494.1 Operon 123 Gene 1 COG1882 Pyruvate-formate lyase; pyruvate-formate lyase 260830 9726316 SPAP_0300 Streptococcus pneumoniae AP200 pyruvate-formate lyase YP_003875895.1 258392 D 574093 CDS YP_003875896.1 307066930 9726317 260849..261517 1 NC_014494.1 Operon 123 Gene 2 COG0176 Transaldolase; transaldolase 261517 9726317 SPAP_0301 Streptococcus pneumoniae AP200 transaldolase YP_003875896.1 260849 D 574093 CDS YP_003875897.1 307066931 9726318 261535..262623 1 NC_014494.1 Operon 123 Gene 3 COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 262623 9726318 SPAP_0302 Streptococcus pneumoniae AP200 glycerol dehydrogenase YP_003875897.1 261535 D 574093 CDS YP_003875898.1 307066932 9726319 263078..265579 1 NC_014494.1 Operon 124 Gene 1 COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 265579 9726319 SPAP_0303 Streptococcus pneumoniae AP200 leucyl-tRNA synthetase YP_003875898.1 263078 D 574093 CDS YP_003875899.1 307066933 9726320 265773..266468 1 NC_014494.1 Operon 125 Gene 1 protein supported gi|116627318|ref|YP_819937.1| acetyltransferase; hypothetical protein 266468 9726320 SPAP_0304 Streptococcus pneumoniae AP200 hypothetical protein YP_003875899.1 265773 D 574093 CDS YP_003875900.1 307066934 9726321 266480..266896 1 NC_014494.1 Operon 125 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 266896 9726321 SPAP_0305 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003875900.1 266480 D 574093 CDS YP_003875901.1 307066935 9726322 complement(267711..267803) 1 NC_014494.1 Operon 126 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 267803 9726322 SPAP_0306 Streptococcus pneumoniae AP200 hypothetical protein YP_003875901.1 267711 R 574093 CDS YP_003875902.1 307066936 9726323 267937..268935 1 NC_014494.1 Operon 127 Gene 1 COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction resolvasome helicase subunit 268935 9726323 SPAP_0307 Streptococcus pneumoniae AP200 Holliday junction resolvasome helicase subunit YP_003875902.1 267937 D 574093 CDS YP_003875903.1 307066937 9726324 268916..269023 1 NC_014494.1 Operon 127 Gene 2 COG3575 Uncharacterized protein conserved in bacteria; hypothetical protein 269023 9726324 SPAP_0308 Streptococcus pneumoniae AP200 hypothetical protein YP_003875903.1 268916 D 574093 CDS YP_003875904.1 307066938 9726325 269024..269488 1 NC_014494.1 Operon 127 Gene 3 COG3575 Uncharacterized protein conserved in bacteria; hypothetical protein 269488 9726325 SPAP_0309 Streptococcus pneumoniae AP200 hypothetical protein YP_003875904.1 269024 D 574093 CDS YP_003875905.1 307066939 9726326 269719..270477 1 NC_014494.1 Operon 128 Gene 1 COG0020 Undecaprenyl pyrophosphate synthase; Undecaprenyl pyrophosphate synthase 270477 9726326 SPAP_0310 Streptococcus pneumoniae AP200 Undecaprenyl pyrophosphate synthase YP_003875905.1 269719 D 574093 CDS YP_003875906.1 307066940 9726327 270486..271289 1 NC_014494.1 Operon 128 Gene 2 COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase 271289 9726327 SPAP_0311 Streptococcus pneumoniae AP200 CDP-diglyceride synthetase YP_003875906.1 270486 D 574093 CDS YP_003875907.1 307066941 9726328 271311..272570 1 NC_014494.1 Operon 128 Gene 3 COG0750 Predicted membrane-associated Zn-dependent proteases 1; hypothetical protein 272570 9726328 SPAP_0312 Streptococcus pneumoniae AP200 hypothetical protein YP_003875907.1 271311 D 574093 CDS YP_003875908.1 307066942 9726329 272583..274436 1 NC_014494.1 Operon 128 Gene 4 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 274436 9726329 SPAP_0313 Streptococcus pneumoniae AP200 prolyl-tRNA synthetase YP_003875908.1 272583 D 574093 CDS YP_003875909.1 307066943 9726330 274536..275915 1 NC_014494.1 Operon 129 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 275915 9726330 SPAP_0314 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003875909.1 274536 D 574093 CDS YP_003875910.1 307066944 9726331 276107..277915 1 NC_014494.1 Operon 130 Gene 1 COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine 6-phosphate synthetase 277915 9726331 SPAP_0315 Streptococcus pneumoniae AP200 glucosamine 6-phosphate synthetase YP_003875910.1 276107 D 574093 CDS YP_003875911.1 307066945 9726332 278186..279235 1 NC_014494.1 Operon 131 Gene 1 protein supported gi|15900201|ref|NP_344805.1| hypothetical protein SP_0267; hypothetical protein 279235 9726332 SPAP_0316 Streptococcus pneumoniae AP200 hypothetical protein YP_003875911.1 278186 D 574093 CDS YP_003875912.1 307066946 9726333 complement(279335..283177) 1 NC_014494.1 Operon 132 Gene 1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; type II secretory pathway pullulanase PulA-like glycosidase 283177 9726333 SPAP_0317 Streptococcus pneumoniae AP200 type II secretory pathway pullulanase PulA-like glycosidase YP_003875912.1 279335 R 574093 CDS YP_003875913.1 307066947 9726334 283594..284007 1 NC_014494.1 Operon 133 Gene 1 protein supported gi|15900205|ref|NP_344809.1| 30S ribosomal protein S12; 30S ribosomal protein S12 284007 9726334 SPAP_0318 Streptococcus pneumoniae AP200 30S ribosomal protein S12 YP_003875913.1 283594 D 574093 CDS YP_003875914.1 307066948 9726335 284027..284497 1 NC_014494.1 Operon 133 Gene 2 protein supported gi|15902293|ref|NP_357843.1| 30S ribosomal protein S7; 30S ribosomal protein S7 284497 9726335 SPAP_0319 Streptococcus pneumoniae AP200 30S ribosomal protein S7 YP_003875914.1 284027 D 574093 CDS YP_003875915.1 307066949 9726336 284922..287003 1 NC_014494.1 Operon 133 Gene 3 COG0480 Translation elongation factors (GTPases); translation elongation factor 287003 9726336 SPAP_0320 Streptococcus pneumoniae AP200 translation elongation factor YP_003875915.1 284922 D 574093 CDS YP_003875916.1 307066950 9726337 287107..291498 1 NC_014494.1 Operon 134 Gene 1 COG2176 DNA polymerase III, alpha subunit (gram-positive type); DNA polymerase III subunit alpha 291498 9726337 SPAP_0321 Streptococcus pneumoniae AP200 DNA polymerase III subunit alpha YP_003875916.1 287107 D 574093 CDS YP_003875917.1 307066951 9726338 291600..291863 1 NC_014494.1 Operon 135 Gene 1 COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 291863 9726338 SPAP_0322 Streptococcus pneumoniae AP200 DNA-damage-inducible protein J YP_003875917.1 291600 D 574093 CDS YP_003875918.1 307066952 9726339 291856..292134 1 NC_014494.1 Operon 135 Gene 2 COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 292134 9726339 SPAP_0323 Streptococcus pneumoniae AP200 hypothetical protein YP_003875918.1 291856 D 574093 CDS YP_003875919.1 307066953 9726340 292155..292307 1 NC_014494.1 Operon 135 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 292307 9726340 SPAP_0324 Streptococcus pneumoniae AP200 hypothetical protein YP_003875919.1 292155 D 574093 CDS YP_003875920.1 307066954 9726341 292329..293570 1 NC_014494.1 Operon 135 Gene 4 COG2309 Leucyl aminopeptidase (aminopeptidase T); leucyl aminopeptidase 293570 9726341 SPAP_0325 Streptococcus pneumoniae AP200 leucyl aminopeptidase YP_003875920.1 292329 D 574093 CDS YP_003875921.1 307066955 9726342 293580..293810 1 NC_014494.1 Operon 135 Gene 5 COG2261 Predicted membrane protein; hypothetical protein 293810 9726342 SPAP_0326 Streptococcus pneumoniae AP200 hypothetical protein YP_003875921.1 293580 D 574093 CDS YP_003875922.1 307066956 9726343 294078..294800 1 NC_014494.1 Operon 136 Gene 1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase 294800 9726343 SPAP_0327 Streptococcus pneumoniae AP200 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase YP_003875922.1 294078 D 574093 CDS YP_003875923.1 307066957 9726344 295017..296351 1 NC_014494.1 Operon 137 Gene 1 COG3579 Aminopeptidase C; aminopeptidase C 296351 9726344 SPAP_0328 Streptococcus pneumoniae AP200 aminopeptidase C YP_003875923.1 295017 D 574093 CDS YP_003875924.1 307066958 9726345 complement(296407..297318) 1 NC_014494.1 Operon 138 Gene 1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 297318 9726345 SPAP_0329 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID YP_003875924.1 296407 R 574093 CDS YP_003875925.1 307066959 9726346 complement(297342..298145) 1 NC_014494.1 Operon 138 Gene 2 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 298145 9726346 SPAP_0330 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC YP_003875925.1 297342 R 574093 CDS YP_003875926.1 307066960 9726347 complement(298173..299162) 1 NC_014494.1 Operon 138 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 299162 9726347 SPAP_0331 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB YP_003875926.1 298173 R 574093 CDS YP_003875927.1 307066961 9726348 complement(299394..300413) 1 NC_014494.1 Operon 139 Gene 1 COG1064 Zn-dependent alcohol dehydrogenases; Zn-dependent alcohol dehydrogenase 300413 9726348 SPAP_0332 Streptococcus pneumoniae AP200 Zn-dependent alcohol dehydrogenase YP_003875927.1 299394 R 574093 CDS YP_003875928.1 307066962 9726349 complement(300752..301564) 1 NC_014494.1 Operon 140 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 301564 9726349 SPAP_0333 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003875928.1 300752 R 574093 CDS YP_003875929.1 307066963 9726350 301754..303172 1 NC_014494.1 Operon 141 Gene 1 COG2252 Permeases; permease 303172 9726350 SPAP_0334 Streptococcus pneumoniae AP200 permease YP_003875929.1 301754 D 574093 CDS YP_003875930.1 307066964 9726351 303225..303932 1 NC_014494.1 Operon 141 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 303932 9726351 SPAP_0335 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003875930.1 303225 D 574093 CDS YP_003875931.1 307066965 9726352 304030..305001 1 NC_014494.1 Operon 142 Gene 1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase-like enzyme 305001 9726352 SPAP_0336 Streptococcus pneumoniae AP200 dihydropteroate synthase-like enzyme YP_003875931.1 304030 D 574093 CDS YP_003875932.1 307066966 9726353 305003..306325 1 NC_014494.1 Operon 142 Gene 2 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 306325 9726353 SPAP_0337 Streptococcus pneumoniae AP200 folylpolyglutamate synthase YP_003875932.1 305003 D 574093 CDS YP_003875933.1 307066967 9726354 306306..306860 1 NC_014494.1 Operon 142 Gene 3 COG0302 GTP cyclohydrolase I; GTP cyclohydrolase I 306860 9726354 SPAP_0338 Streptococcus pneumoniae AP200 GTP cyclohydrolase I YP_003875933.1 306306 D 574093 CDS YP_003875934.1 307066968 9726355 306903..307715 1 NC_014494.1 Operon 142 Gene 4 protein supported gi|148994682|ref|ZP_01823786.1| 50S ribosomal protein L13; hypothetical protein 307715 9726355 SPAP_0339 Streptococcus pneumoniae AP200 hypothetical protein YP_003875934.1 306903 D 574093 CDS YP_003875935.1 307066969 9726356 complement(307865..308182) 1 NC_014494.1 Operon 143 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 308182 9726356 SPAP_0340 Streptococcus pneumoniae AP200 hypothetical protein YP_003875935.1 307865 R 574093 CDS YP_003875936.1 307066970 9726357 308539..308985 1 NC_014494.1 Operon 144 Gene 1 protein supported gi|15900228|ref|NP_344832.1| 50S ribosomal protein L13; hypothetical protein 308985 9726357 SPAP_0341 Streptococcus pneumoniae AP200 hypothetical protein YP_003875936.1 308539 D 574093 CDS YP_003875937.1 307066971 9726358 309004..309396 1 NC_014494.1 Operon 144 Gene 2 protein supported gi|15902316|ref|NP_357866.1| 30S ribosomal protein S9; 30S ribosomal protein S9 309396 9726358 SPAP_0342 Streptococcus pneumoniae AP200 30S ribosomal protein S9 YP_003875937.1 309004 D 574093 CDS YP_003875938.1 307066972 9726359 complement(309657..310079) 1 NC_014494.1 Operon 145 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 310079 9726359 SPAP_0343 Streptococcus pneumoniae AP200 hypothetical protein YP_003875938.1 309657 R 574093 CDS YP_003875939.1 307066973 9726360 310226..310402 1 NC_014494.1 Operon 146 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 310402 9726360 SPAP_0344 Streptococcus pneumoniae AP200 hypothetical protein YP_003875939.1 310226 D 574093 CDS YP_003875940.1 307066974 9726361 310803..313016 1 NC_014494.1 Operon 147 Gene 1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; alpha-glucosidase 313016 9726361 SPAP_0345 Streptococcus pneumoniae AP200 alpha-glucosidase YP_003875940.1 310803 D 574093 CDS YP_003875941.1 307066975 9726362 complement(313238..313714) 1 NC_014494.1 Operon 148 Gene 1 COG0386 Glutathione peroxidase; glutathione peroxidase 313714 9726362 SPAP_0346 Streptococcus pneumoniae AP200 glutathione peroxidase YP_003875941.1 313238 R 574093 CDS YP_003875942.1 307066976 9726363 313937..317140 1 NC_014494.1 hyaluronidase; hypothetical protein 317140 9726363 SPAP_0347 Streptococcus pneumoniae AP200 hypothetical protein YP_003875942.1 313937 D 574093 CDS YP_003875943.1 307066977 9726364 317679..317912 1 NC_014494.1 Operon 150 Gene 1 protein supported gi|148996730|ref|ZP_01824448.1| 30S ribosomal protein S9; hypothetical protein 317912 9726364 SPAP_0348 Streptococcus pneumoniae AP200 hypothetical protein YP_003875943.1 317679 D 574093 CDS YP_003875944.1 307066978 9726365 complement(318288..318917) 1 NC_014494.1 Operon 151 Gene 1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase 318917 9726365 SPAP_0349 Streptococcus pneumoniae AP200 2-keto-3-deoxy-6-phosphogluconate aldolase YP_003875944.1 318288 R 574093 CDS YP_003875945.1 307066979 9726366 complement(318927..319928) 1 NC_014494.1 Operon 151 Gene 2 COG0524 Sugar kinases, ribokinase family; sugar kinase 319928 9726366 SPAP_0350 Streptococcus pneumoniae AP200 sugar kinase YP_003875945.1 318927 R 574093 CDS YP_003875946.1 307066980 9726367 complement(319959..320600) 1 NC_014494.1 Operon 151 Gene 3 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB 320600 9726367 SPAP_0351 Streptococcus pneumoniae AP200 ribose 5-phosphate isomerase RpiB YP_003875946.1 319959 R 574093 CDS YP_003875947.1 307066981 9726368 complement(320619..321434) 1 NC_014494.1 Operon 151 Gene 4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 321434 9726368 SPAP_0352 Streptococcus pneumoniae AP200 dehydrogenase YP_003875947.1 320619 R 574093 CDS YP_003875948.1 307066982 9726369 321706..322140 1 NC_014494.1 Operon 152 Gene 1 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA 322140 9726369 SPAP_0353 Streptococcus pneumoniae AP200 PTS system mannose/fructose-specific transporter subunit IIA YP_003875948.1 321706 D 574093 CDS YP_003875949.1 307066983 9726370 322152..323342 1 NC_014494.1 Operon 152 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 323342 9726370 SPAP_0354 Streptococcus pneumoniae AP200 hypothetical protein YP_003875949.1 322152 D 574093 CDS YP_003875950.1 307066984 9726371 323353..323844 1 NC_014494.1 Operon 152 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 323844 9726371 SPAP_0355 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB YP_003875950.1 323353 D 574093 CDS YP_003875951.1 307066985 9726372 323859..324638 1 NC_014494.1 Operon 152 Gene 4 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 324638 9726372 SPAP_0356 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC YP_003875951.1 323859 D 574093 CDS YP_003875952.1 307066986 9726373 324625..325443 1 NC_014494.1 Operon 152 Gene 5 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 325443 9726373 SPAP_0357 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID YP_003875952.1 324625 D 574093 CDS YP_003875953.1 307066987 9726374 325455..325736 1 NC_014494.1 Operon 152 Gene 6 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC 325736 9726374 SPAP_0358 Streptococcus pneumoniae AP200 preprotein translocase subunit YajC YP_003875953.1 325455 D 574093 CDS YP_003875954.1 307066988 9726375 325758..327659 1 NC_014494.1 Operon 152 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 327659 9726375 SPAP_0359 Streptococcus pneumoniae AP200 hypothetical protein YP_003875954.1 325758 D 574093 CDS YP_003875955.1 307066989 9726376 327719..328720 1 NC_014494.1 Operon 152 Gene 8 COG1609 Transcriptional regulators; transcriptional regulator 328720 9726376 SPAP_0360 Streptococcus pneumoniae AP200 transcriptional regulator YP_003875955.1 327719 D 574093 CDS YP_003875956.1 307066990 9726377 complement(328830..329165) 1 NC_014494.1 Operon 153 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 329165 9726377 SPAP_0361 Streptococcus pneumoniae AP200 hypothetical protein YP_003875956.1 328830 R 574093 CDS YP_003875957.1 307066991 9726378 complement(329176..329418) 1 NC_014494.1 Operon 153 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 329418 9726378 SPAP_0362 Streptococcus pneumoniae AP200 hypothetical protein YP_003875957.1 329176 R 574093 CDS YP_003875958.1 307066992 9726379 complement(329677..329970) 1 NC_014494.1 Operon 154 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 329970 9726379 SPAP_0363 Streptococcus pneumoniae AP200 hypothetical protein YP_003875958.1 329677 R 574093 CDS YP_003875959.1 307066993 9726380 complement(329986..330180) 1 NC_014494.1 Operon 154 Gene 2 COG1476 Predicted transcriptional regulators; putative transcriptional regulator 330180 9726380 SPAP_0364 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003875959.1 329986 R 574093 CDS YP_003875960.1 307066994 9726381 330346..331296 1 NC_014494.1 Operon 155 Gene 1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; putative S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis 331296 9726381 SPAP_0365 Streptococcus pneumoniae AP200 putative S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis YP_003875960.1 330346 D 574093 CDS YP_003875961.1 307066995 9726382 331308..331625 1 NC_014494.1 Operon 155 Gene 2 COG4839 Protein required for the initiation of cell division; cell division initiation protein 331625 9726382 SPAP_0366 Streptococcus pneumoniae AP200 cell division initiation protein YP_003875961.1 331308 D 574093 CDS YP_003875962.1 307066996 9726383 331629..333881 1 NC_014494.1 Operon 155 Gene 3 COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein FtsI 333881 9726383 SPAP_0367 Streptococcus pneumoniae AP200 cell division protein FtsI YP_003875962.1 331629 D 574093 CDS YP_003875963.1 307066997 9726384 333883..334863 1 NC_014494.1 Operon 155 Gene 4 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase 334863 9726384 SPAP_0368 Streptococcus pneumoniae AP200 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_003875963.1 333883 D 574093 CDS YP_003875964.1 307066998 9726385 335427..337532 1 NC_014494.1 Operon 156 Gene 1 protein supported gi|163764771|ref|ZP_02171825.1| ribosomal protein S8; hypothetical protein 337532 9726385 SPAP_0369 Streptococcus pneumoniae AP200 hypothetical protein YP_003875964.1 335427 D 574093 CDS YP_003875965.1 307066999 9726386 complement(337828..338310) 1 NC_014494.1 Operon 157 Gene 1 COG1854 LuxS protein involved in autoinducer AI2 synthesis; LuxS protein involved in autoinducer AI2 synthesis 338310 9726386 SPAP_0370 Streptococcus pneumoniae AP200 LuxS protein involved in autoinducer AI2 synthesis YP_003875965.1 337828 R 574093 CDS YP_003875966.1 307067000 9726387 complement(338405..339889) 1 NC_014494.1 Operon 157 Gene 2 COG4868 Uncharacterized protein conserved in bacteria; hypothetical protein 339889 9726387 SPAP_0371 Streptococcus pneumoniae AP200 hypothetical protein YP_003875966.1 338405 R 574093 CDS YP_003875967.1 307067001 9726388 340042..341652 1 NC_014494.1 Operon 158 Gene 1 COG0366 Glycosidases; glucan 1,6-alpha-glucosidase 341652 9726388 SPAP_0372 Streptococcus pneumoniae AP200 glucan 1,6-alpha-glucosidase YP_003875967.1 340042 D 574093 CDS YP_003875968.1 307067002 9726389 complement(341783..343192) 1 NC_014494.1 transposase-like protein, IS1202 343192 9726389 SPAP_0373 Streptococcus pneumoniae AP200 transposase-like protein, IS1202 YP_003875968.1 341783 R 574093 CDS YP_003875969.1 307067003 9726390 343368..344813 1 NC_014494.1 Operon 160 Gene 1 COG1316 Transcriptional regulator; integral membrane regulatory protein Wzg 344813 wzg 9726390 wzg Streptococcus pneumoniae AP200 integral membrane regulatory protein Wzg YP_003875969.1 343368 D 574093 CDS YP_003875970.1 307067004 9726391 344815..345546 1 NC_014494.1 Operon 160 Gene 2 COG4464 Capsular polysaccharide biosynthesis protein; protein-tyrosine phosphatase Wzh 345546 wzh 9726391 wzh Streptococcus pneumoniae AP200 protein-tyrosine phosphatase Wzh YP_003875970.1 344815 D 574093 CDS YP_003875971.1 307067005 9726392 345555..346247 1 NC_014494.1 Operon 160 Gene 3 COG3944 Capsular polysaccharide biosynthesis protein; capsular polysaccharide biosynthesis protein Wzd 346247 wzd 9726392 wzd Streptococcus pneumoniae AP200 capsular polysaccharide biosynthesis protein Wzd YP_003875971.1 345555 D 574093 CDS YP_003875972.1 307067006 9726393 346257..346946 1 NC_014494.1 Operon 160 Gene 4 COG0489 ATPases involved in chromosome partitioning; tyrosine-protein kinase Wze 346946 wze 9726393 wze Streptococcus pneumoniae AP200 tyrosine-protein kinase Wze YP_003875972.1 346257 D 574093 CDS YP_003875973.1 307067007 9726394 346961..348322 1 NC_014494.1 Operon 160 Gene 5 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase) 348322 wchA 9726394 wchA Streptococcus pneumoniae AP200 undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase) YP_003875973.1 346961 D 574093 CDS YP_003875974.1 307067008 9726395 348326..348775 1 NC_014494.1 Operon 160 Gene 6 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; putative glycosyl transferase enhancer 348775 wchJ 9726395 wchJ Streptococcus pneumoniae AP200 putative glycosyl transferase enhancer YP_003875974.1 348326 D 574093 CDS YP_003875975.1 307067009 9726396 348775..349254 1 NC_014494.1 Operon 160 Gene 7 COG5017 Uncharacterized conserved protein; putative glycosyl transferase 349254 wchK 9726396 wchK Streptococcus pneumoniae AP200 putative glycosyl transferase YP_003875975.1 348775 D 574093 CDS YP_003875976.1 307067010 9726397 349496..350593 1 NC_014494.1 Operon 161 Gene 1 COG0438 Glycosyltransferase; putative glycosyl transferase 350593 wcyK 9726397 wcyK Streptococcus pneumoniae AP200 putative glycosyl transferase YP_003875976.1 349496 D 574093 CDS YP_003875977.1 307067011 9726398 350615..351274 1 NC_014494.1 Operon 161 Gene 2 COG3955 Exopolysaccharide biosynthesis protein; putative acetyl transferase 351274 wcwC 9726398 wcwC Streptococcus pneumoniae AP200 putative acetyl transferase YP_003875977.1 350615 D 574093 CDS YP_003875978.1 307067012 9726399 351271..351993 1 NC_014494.1 Operon 161 Gene 3 COG3774 Mannosyltransferase OCH1 and related enzymes; putative glycosyl transferase 351993 wcrL 9726399 wcrL Streptococcus pneumoniae AP200 putative glycosyl transferase YP_003875978.1 351271 D 574093 CDS YP_003875979.1 307067013 9726400 351990..353162 1 NC_014494.1 oligosaccharide repeat unit polymerase Wzy 353162 wzy 9726400 wzy Streptococcus pneumoniae AP200 oligosaccharide repeat unit polymerase Wzy YP_003875979.1 351990 D 574093 CDS YP_003875980.1 307067014 9726401 353152..353652 1 NC_014494.1 Operon 161 Gene 5 COG0110 Acetyltransferase (isoleucine patch superfamily); putative acetyl transferase 353652 wcwT 9726401 wcwT Streptococcus pneumoniae AP200 putative acetyl transferase YP_003875980.1 353152 D 574093 CDS YP_003875981.1 307067015 9726402 353662..354849 1 NC_014494.1 Operon 161 Gene 6 COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; putative glycerol phosphotransferase 354849 wcwU 9726402 wcwU Streptococcus pneumoniae AP200 putative glycerol phosphotransferase YP_003875981.1 353662 D 574093 CDS YP_003875982.1 307067016 9726403 354806..356269 1 NC_014494.1 Operon 161 Gene 7 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx 356269 wzx 9726403 wzx Streptococcus pneumoniae AP200 flippase Wzx YP_003875982.1 354806 D 574093 CDS YP_003875983.1 307067017 9726404 356383..356775 1 NC_014494.1 Operon 162 Gene 1 COG0615 Cytidylyltransferase; CDP-glycerol-1-phosphate biosynthetic protein Gct 356775 gct 9726404 gct Streptococcus pneumoniae AP200 CDP-glycerol-1-phosphate biosynthetic protein Gct YP_003875983.1 356383 D 574093 CDS YP_003875984.1 307067018 9726405 357137..358165 1 NC_014494.1 putative acetyl transferase 358165 wcjE 9726405 wcjE Streptococcus pneumoniae AP200 putative acetyl transferase YP_003875984.1 357137 D 574093 CDS YP_003875985.1 307067019 9726406 358343..360325 1 NC_014494.1 Operon 164 Gene 1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic protein 360325 9726406 SPAP_0390 Streptococcus pneumoniae AP200 oligopeptide ABC transporter periplasmic protein YP_003875985.1 358343 D 574093 CDS YP_003875986.1 307067020 9726407 360329..360520 1 NC_014494.1 Operon 164 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 360520 9726407 SPAP_0391 Streptococcus pneumoniae AP200 hypothetical protein YP_003875986.1 360329 D 574093 CDS YP_003875987.1 307067021 9726408 360626..365929 1 NC_014494.1 cell wall surface anchor family protein; hypothetical protein 365929 9726408 SPAP_0392 Streptococcus pneumoniae AP200 hypothetical protein YP_003875987.1 360626 D 574093 CDS YP_003875988.1 307067022 9726409 complement(366096..368255) 1 NC_014494.1 Operon 166 Gene 1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase 368255 9726409 SPAP_0393 Streptococcus pneumoniae AP200 membrane carboxypeptidase YP_003875988.1 366096 R 574093 CDS YP_003875989.1 307067023 9726410 complement(368252..368848) 1 NC_014494.1 Operon 166 Gene 2 COG3331 Penicillin-binding protein-related factor A, putative recombinase; penicillin-binding protein-related factor A, putative recombinase 368848 9726410 SPAP_0394 Streptococcus pneumoniae AP200 penicillin-binding protein-related factor A, putative recombinase YP_003875989.1 368252 R 574093 CDS YP_003875990.1 307067024 9726411 368914..369441 1 NC_014494.1 Operon 167 Gene 1 COG4474 Uncharacterized protein conserved in bacteria; hypothetical protein 369441 9726411 SPAP_0395 Streptococcus pneumoniae AP200 hypothetical protein YP_003875990.1 368914 D 574093 CDS YP_003875991.1 307067025 9726412 369499..369840 1 NC_014494.1 Operon 167 Gene 2 COG3599 Cell division initiation protein; cell division initiation protein 369840 9726412 SPAP_0396 Streptococcus pneumoniae AP200 cell division initiation protein YP_003875991.1 369499 D 574093 CDS YP_003875992.1 307067026 9726413 complement(369829..370038) 1 NC_014494.1 Operon 168 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 370038 9726413 SPAP_0397 Streptococcus pneumoniae AP200 hypothetical protein YP_003875992.1 369829 R 574093 CDS YP_003875993.1 307067027 9726414 370326..371483 1 NC_014494.1 Operon 169 Gene 1 COG0116 Predicted N6-adenine-specific DNA methylase; putative N6-adenine-specific DNA methylase 371483 9726414 SPAP_0398 Streptococcus pneumoniae AP200 putative N6-adenine-specific DNA methylase YP_003875993.1 370326 D 574093 CDS YP_003875994.1 307067028 9726415 371496..372890 1 NC_014494.1 Operon 169 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 372890 9726415 SPAP_0399 Streptococcus pneumoniae AP200 hypothetical protein YP_003875994.1 371496 D 574093 CDS YP_003875995.1 307067029 9726416 372966..374390 1 NC_014494.1 Operon 169 Gene 3 COG0362 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 374390 9726416 SPAP_0400 Streptococcus pneumoniae AP200 6-phosphogluconate dehydrogenase YP_003875995.1 372966 D 574093 CDS YP_003875996.1 307067030 9726417 374402..375091 1 NC_014494.1 Operon 169 Gene 4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 375091 9726417 SPAP_0401 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003875996.1 374402 D 574093 CDS YP_003875997.1 307067031 9726418 375189..376208 1 NC_014494.1 Operon 169 Gene 5 COG5263 FOG: Choline binding protein F; choline binding protein F 376208 9726418 SPAP_0402 Streptococcus pneumoniae AP200 choline binding protein F YP_003875997.1 375189 D 574093 CDS YP_003875998.1 307067032 9726419 complement(376326..377582) 1 NC_014494.1 Operon 170 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 377582 9726419 SPAP_0403 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003875998.1 376326 R 574093 CDS YP_003875999.1 307067033 9726420 complement(377717..378187) 1 NC_014494.1 Operon 171 Gene 1 COG4403 Lantibiotic modifying enzyme; lantibiotic modifying enzyme 378187 9726420 SPAP_0404 Streptococcus pneumoniae AP200 lantibiotic modifying enzyme YP_003875999.1 377717 R 574093 CDS YP_003876000.1 307067034 9726421 complement(378087..378476) 1 NC_014494.1 Operon 171 Gene 2 COG4403 Lantibiotic modifying enzyme; lantibiotic modifying enzyme 378476 9726421 SPAP_0405 Streptococcus pneumoniae AP200 lantibiotic modifying enzyme YP_003876000.1 378087 R 574093 CDS YP_003876001.1 307067035 9726422 378436..378630 1 NC_014494.1 Operon 172 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 378630 9726422 SPAP_0406 Streptococcus pneumoniae AP200 hypothetical protein YP_003876001.1 378436 D 574093 CDS YP_003876002.1 307067036 9726423 379088..379417 1 NC_014494.1 Operon 173 Gene 1 COG5263 FOG: Choline binding protein C; choline binding protein C 379417 9726423 SPAP_0407 Streptococcus pneumoniae AP200 choline binding protein C YP_003876002.1 379088 D 574093 CDS YP_003876003.1 307067037 9726424 379539..380417 1 NC_014494.1 Operon 174 Gene 1 COG1577 Mevalonate kinase; mevalonate kinase 380417 9726424 SPAP_0408 Streptococcus pneumoniae AP200 mevalonate kinase YP_003876003.1 379539 D 574093 CDS YP_003876004.1 307067038 9726425 380399..381352 1 NC_014494.1 Operon 174 Gene 2 COG3407 Mevalonate pyrophosphate decarboxylase; mevalonate pyrophosphate decarboxylase 381352 9726425 SPAP_0409 Streptococcus pneumoniae AP200 mevalonate pyrophosphate decarboxylase YP_003876004.1 380399 D 574093 CDS YP_003876005.1 307067039 9726426 381339..382346 1 NC_014494.1 Operon 174 Gene 3 COG1577 Mevalonate kinase; mevalonate kinase 382346 9726426 SPAP_0410 Streptococcus pneumoniae AP200 mevalonate kinase YP_003876005.1 381339 D 574093 CDS YP_003876006.1 307067040 9726427 382330..383340 1 NC_014494.1 Operon 174 Gene 4 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 383340 9726427 SPAP_0411 Streptococcus pneumoniae AP200 L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase YP_003876006.1 382330 D 574093 CDS YP_003876007.1 307067041 9726428 383417..384115 1 NC_014494.1 Operon 174 Gene 5 COG4758 Predicted membrane protein; hypothetical protein 384115 9726428 SPAP_0412 Streptococcus pneumoniae AP200 hypothetical protein YP_003876007.1 383417 D 574093 CDS YP_003876008.1 307067042 9726429 384112..385107 1 NC_014494.1 Operon 174 Gene 6 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 385107 9726429 SPAP_0413 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003876008.1 384112 D 574093 CDS YP_003876009.1 307067043 9726430 385121..385753 1 NC_014494.1 Operon 174 Gene 7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; CheY-like receiver/HTH DNA-binding domain-containing response regulator 385753 9726430 SPAP_0414 Streptococcus pneumoniae AP200 CheY-like receiver/HTH DNA-binding domain-containing response regulator YP_003876009.1 385121 D 574093 CDS YP_003876010.1 307067044 9726431 385754..385963 1 NC_014494.1 Operon 174 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 385963 9726431 SPAP_0415 Streptococcus pneumoniae AP200 hypothetical protein YP_003876010.1 385754 D 574093 CDS YP_003876011.1 307067045 9726432 386346..386522 1 NC_014494.1 Operon 175 Gene 1 COG4912 Predicted DNA alkylation repair enzyme; putative DNA alkylation repair enzyme 386522 9726432 SPAP_0416 Streptococcus pneumoniae AP200 putative DNA alkylation repair enzyme YP_003876011.1 386346 D 574093 CDS YP_003876012.1 307067046 9726433 386672..387586 1 NC_014494.1 Operon 176 Gene 1 COG3591 V8-like Glu-specific endopeptidase; V8-like Glu-specific endopeptidase 387586 9726433 SPAP_0417 Streptococcus pneumoniae AP200 V8-like Glu-specific endopeptidase YP_003876012.1 386672 D 574093 CDS YP_003876013.1 307067047 9726434 388014..388244 1 NC_014494.1 Operon 177 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 388244 9726434 SPAP_0418 Streptococcus pneumoniae AP200 hypothetical protein YP_003876013.1 388014 D 574093 CDS YP_003876014.1 307067048 9726435 388438..389721 1 NC_014494.1 Operon 178 Gene 1 COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); FKBP-type peptidyl-prolyl cis-trans isomerase 389721 9726435 SPAP_0419 Streptococcus pneumoniae AP200 FKBP-type peptidyl-prolyl cis-trans isomerase YP_003876014.1 388438 D 574093 CDS YP_003876015.1 307067049 9726436 complement(389769..390446) 1 NC_014494.1 Operon 179 Gene 1 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha 390446 9726436 SPAP_0420 Streptococcus pneumoniae AP200 ATP-dependent exoDNAse (exonuclease V) subunit alpha YP_003876015.1 389769 R 574093 CDS YP_003876016.1 307067050 9726437 complement(390500..392134) 1 NC_014494.1 Operon 179 Gene 2 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha 392134 9726437 SPAP_0421 Streptococcus pneumoniae AP200 ATP-dependent exoDNAse (exonuclease V) subunit alpha YP_003876016.1 390500 R 574093 CDS YP_003876017.1 307067051 9726438 complement(392413..392913) 1 NC_014494.1 Operon 180 Gene 1 COG0681 Signal peptidase I; signal peptidase I 392913 9726438 SPAP_0422 Streptococcus pneumoniae AP200 signal peptidase I YP_003876017.1 392413 R 574093 CDS YP_003876018.1 307067052 9726439 complement(393031..393912) 1 NC_014494.1 Operon 181 Gene 1 COG1039 Ribonuclease HIII; ribonuclease HIII 393912 9726439 SPAP_0423 Streptococcus pneumoniae AP200 ribonuclease HIII YP_003876018.1 393031 R 574093 CDS YP_003876019.1 307067053 9726440 393999..394301 1 NC_014494.1 Operon 182 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 394301 9726440 SPAP_0424 Streptococcus pneumoniae AP200 hypothetical protein YP_003876019.1 393999 D 574093 CDS YP_003876020.1 307067054 9726441 394298..394846 1 NC_014494.1 Operon 182 Gene 2 COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein 394846 9726441 SPAP_0425 Streptococcus pneumoniae AP200 hypothetical protein YP_003876020.1 394298 D 574093 CDS YP_003876021.1 307067055 9726442 394950..397286 1 NC_014494.1 Operon 183 Gene 1 COG1193 Mismatch repair ATPase (MutS family); mismatch repair ATPase 397286 9726442 SPAP_0426 Streptococcus pneumoniae AP200 mismatch repair ATPase YP_003876021.1 394950 D 574093 CDS YP_003876022.1 307067056 9726443 397629..398951 1 NC_014494.1 Operon 184 Gene 1 COG1115 Na+/alanine symporter; Na+/alanine symporter 398951 9726443 SPAP_0427 Streptococcus pneumoniae AP200 Na+/alanine symporter YP_003876022.1 397629 D 574093 CDS YP_003876023.1 307067057 9726444 399169..399717 1 NC_014494.1 Operon 185 Gene 1 COG2128 Uncharacterized conserved protein; hypothetical protein 399717 9726444 SPAP_0428 Streptococcus pneumoniae AP200 hypothetical protein YP_003876023.1 399169 D 574093 CDS YP_003876024.1 307067058 9726445 399827..400726 1 NC_014494.1 Operon 186 Gene 1 COG1275 Tellurite resistance protein and related permeases; tellurite resistance protein-like permease 400726 9726445 SPAP_0429 Streptococcus pneumoniae AP200 tellurite resistance protein-like permease YP_003876024.1 399827 D 574093 CDS YP_003876025.1 307067059 9726446 complement(400751..402025) 1 NC_014494.1 Operon 187 Gene 1 COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase 402025 9726446 SPAP_0430 Streptococcus pneumoniae AP200 seryl-tRNA synthetase YP_003876025.1 400751 R 574093 CDS YP_003876026.1 307067060 9726447 complement(402239..402610) 1 NC_014494.1 Operon 188 Gene 1 COG4687 Uncharacterized protein conserved in bacteria; hypothetical protein 402610 9726447 SPAP_0431 Streptococcus pneumoniae AP200 hypothetical protein YP_003876026.1 402239 R 574093 CDS YP_003876027.1 307067061 9726448 complement(402613..403977) 1 NC_014494.1 Operon 188 Gene 2 COG0527 Aspartokinases; aspartokinase 403977 9726448 SPAP_0432 Streptococcus pneumoniae AP200 aspartokinase YP_003876027.1 402613 R 574093 CDS YP_003876028.1 307067062 9726449 404302..405087 1 NC_014494.1 Operon 189 Gene 1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/carnithine racemase 405087 9726449 SPAP_0433 Streptococcus pneumoniae AP200 enoyl-CoA hydratase/carnithine racemase YP_003876028.1 404302 D 574093 CDS YP_003876029.1 307067063 9726450 405181..405615 1 NC_014494.1 Operon 189 Gene 2 COG1846 Transcriptional regulators; transcriptional regulator 405615 9726450 SPAP_0434 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876029.1 405181 D 574093 CDS YP_003876030.1 307067064 9726451 405615..406589 1 NC_014494.1 Operon 189 Gene 3 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase 406589 9726451 SPAP_0435 Streptococcus pneumoniae AP200 3-oxoacyl-ACP synthase YP_003876030.1 405615 D 574093 CDS YP_003876031.1 307067065 9726452 406649..406873 1 NC_014494.1 Operon 189 Gene 4 COG0236 Acyl carrier protein; acyl carrier protein 406873 9726452 SPAP_0436 Streptococcus pneumoniae AP200 acyl carrier protein YP_003876031.1 406649 D 574093 CDS YP_003876032.1 307067066 9726453 406992..407966 1 NC_014494.1 Operon 190 Gene 1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase; dioxygenase 407966 9726453 SPAP_0437 Streptococcus pneumoniae AP200 dioxygenase YP_003876032.1 406992 D 574093 CDS YP_003876033.1 307067067 9726454 407959..408879 1 NC_014494.1 Operon 190 Gene 2 COG0331 (acyl-carrier-protein) S-malonyltransferase; (acyl-carrier-protein) S-malonyltransferase 408879 9726454 SPAP_0438 Streptococcus pneumoniae AP200 (acyl-carrier-protein) S-malonyltransferase YP_003876033.1 407959 D 574093 CDS YP_003876034.1 307067068 9726455 408913..409644 1 NC_014494.1 Operon 190 Gene 3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 409644 9726455 SPAP_0439 Streptococcus pneumoniae AP200 dehydrogenase YP_003876034.1 408913 D 574093 CDS YP_003876035.1 307067069 9726456 409666..410901 1 NC_014494.1 Operon 190 Gene 4 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-ACP synthase 410901 9726456 SPAP_0440 Streptococcus pneumoniae AP200 3-oxoacyl-ACP synthase YP_003876035.1 409666 D 574093 CDS YP_003876036.1 307067070 9726457 410904..411389 1 NC_014494.1 Operon 190 Gene 5 COG0511 Biotin carboxyl carrier protein; biotin carboxyl carrier protein 411389 9726457 SPAP_0441 Streptococcus pneumoniae AP200 biotin carboxyl carrier protein YP_003876036.1 410904 D 574093 CDS YP_003876037.1 307067071 9726458 411386..411808 1 NC_014494.1 Operon 190 Gene 6 COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase 411808 9726458 SPAP_0442 Streptococcus pneumoniae AP200 (3R)-hydroxymyristoyl-ACP dehydratase YP_003876037.1 411386 D 574093 CDS YP_003876038.1 307067072 9726459 411820..413187 1 NC_014494.1 Operon 190 Gene 7 COG0439 Biotin carboxylase; biotin carboxylase 413187 9726459 SPAP_0443 Streptococcus pneumoniae AP200 biotin carboxylase YP_003876038.1 411820 D 574093 CDS YP_003876039.1 307067073 9726460 413224..414090 1 NC_014494.1 Operon 190 Gene 8 COG0777 Acetyl-CoA carboxylase beta subunit; acetyl-Coa carboxylase subunit beta 414090 9726460 SPAP_0444 Streptococcus pneumoniae AP200 acetyl-Coa carboxylase subunit beta YP_003876039.1 413224 D 574093 CDS YP_003876040.1 307067074 9726461 414087..414854 1 NC_014494.1 Operon 190 Gene 9 COG0825 Acetyl-CoA carboxylase alpha subunit; acetyl-Coa carboxylase subunit alpha 414854 9726461 SPAP_0445 Streptococcus pneumoniae AP200 acetyl-Coa carboxylase subunit alpha YP_003876040.1 414087 D 574093 CDS YP_003876041.1 307067075 9726462 415013..415198 1 NC_014494.1 Operon 191 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 415198 9726462 SPAP_0446 Streptococcus pneumoniae AP200 hypothetical protein YP_003876041.1 415013 D 574093 CDS YP_003876042.1 307067076 9726463 415216..415689 1 NC_014494.1 Operon 191 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 415689 9726463 SPAP_0447 Streptococcus pneumoniae AP200 hypothetical protein YP_003876042.1 415216 D 574093 CDS YP_003876043.1 307067077 9726464 complement(415988..416410) 1 NC_014494.1 Operon 192 Gene 1 COG0781 Transcription termination factor; transcription termination factor 416410 9726464 SPAP_0448 Streptococcus pneumoniae AP200 transcription termination factor YP_003876043.1 415988 R 574093 CDS YP_003876044.1 307067078 9726465 complement(416403..416792) 1 NC_014494.1 Operon 192 Gene 2 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein 416792 9726465 SPAP_0449 Streptococcus pneumoniae AP200 hypothetical protein YP_003876044.1 416403 R 574093 CDS YP_003876045.1 307067079 9726466 complement(416814..417374) 1 NC_014494.1 EF-P/eIF-5A; Operon 192 Gene 3 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); translation elongation factor P / translation initiation factor 5A 417374 9726466 SPAP_0450 Streptococcus pneumoniae AP200 translation elongation factor P / translation initiation factor 5A YP_003876045.1 416814 R 574093 CDS YP_003876046.1 307067080 9726467 complement(417503..418945) 1 NC_014494.1 Operon 193 Gene 1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit B 418945 9726467 SPAP_0451 Streptococcus pneumoniae AP200 Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit B YP_003876046.1 417503 R 574093 CDS YP_003876047.1 307067081 9726468 complement(418945..420411) 1 NC_014494.1 Operon 193 Gene 2 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit A-like amidase 420411 9726468 SPAP_0452 Streptococcus pneumoniae AP200 Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit A-like amidase YP_003876047.1 418945 R 574093 CDS YP_003876048.1 307067082 9726469 complement(420411..420713) 1 NC_014494.1 Operon 193 Gene 3 COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit C 420713 9726469 SPAP_0453 Streptococcus pneumoniae AP200 Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit C YP_003876048.1 420411 R 574093 CDS YP_003876049.1 307067083 9726470 420926..422470 1 NC_014494.1 Operon 194 Gene 1 COG4108 Peptide chain release factor RF-3; peptide chain release factor RF-3 422470 9726470 SPAP_0454 Streptococcus pneumoniae AP200 peptide chain release factor RF-3 YP_003876049.1 420926 D 574093 CDS YP_003876050.1 307067084 9726471 422898..423095 1 NC_014494.1 Operon 195 Gene 1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide biosynthesis protein 423095 9726471 SPAP_0455 Streptococcus pneumoniae AP200 lipopolysaccharide biosynthesis protein YP_003876050.1 422898 D 574093 CDS YP_003876051.1 307067085 9726472 423498..423686 1 NC_014494.1 Operon 196 Gene 1 protein supported gi|15900358|ref|NP_344962.1| 50S ribosomal protein L28; hypothetical protein 423686 9726472 SPAP_0456 Streptococcus pneumoniae AP200 hypothetical protein YP_003876051.1 423498 D 574093 CDS YP_003876052.1 307067086 9726473 423843..424208 1 NC_014494.1 Operon 197 Gene 1 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein 424208 9726473 SPAP_0457 Streptococcus pneumoniae AP200 hypothetical protein YP_003876052.1 423843 D 574093 CDS YP_003876053.1 307067087 9726474 424211..425878 1 NC_014494.1 Operon 197 Gene 2 COG1461 Predicted kinase related to dihydroxyacetone kinase; putative kinase 425878 9726474 SPAP_0458 Streptococcus pneumoniae AP200 putative kinase YP_003876053.1 424211 D 574093 CDS YP_003876054.1 307067088 9726475 426078..427778 1 NC_014494.1 acetolactate synthase; pyruvate dehydrogenase (cytochrome); glyoxylate carboligase; l phosphonopyruvate decarboxylase; Operon 198 Gene 1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; thiamine pyrophosphate-requiring enzyme 427778 9726475 SPAP_0459 Streptococcus pneumoniae AP200 thiamine pyrophosphate-requiring enzyme YP_003876054.1 426078 D 574093 CDS YP_003876055.1 307067089 9726476 427771..428247 1 NC_014494.1 Operon 198 Gene 2 COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase small subunit 428247 9726476 SPAP_0460 Streptococcus pneumoniae AP200 acetolactate synthase small subunit YP_003876055.1 427771 D 574093 CDS YP_003876056.1 307067090 9726477 428313..429335 1 NC_014494.1 Operon 198 Gene 3 COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase 429335 9726477 SPAP_0461 Streptococcus pneumoniae AP200 ketol-acid reductoisomerase YP_003876056.1 428313 D 574093 CDS YP_003876057.1 307067091 9726478 429538..429678 1 NC_014494.1 Operon 199 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 429678 9726478 SPAP_0462 Streptococcus pneumoniae AP200 hypothetical protein YP_003876057.1 429538 D 574093 CDS YP_003876058.1 307067092 9726479 429916..430272 1 NC_014494.1 Operon 200 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 430272 9726479 SPAP_0463 Streptococcus pneumoniae AP200 hypothetical protein YP_003876058.1 429916 D 574093 CDS YP_003876059.1 307067093 9726480 430322..431572 1 NC_014494.1 Operon 200 Gene 2 COG1171 Threonine dehydratase; threonine dehydratase 431572 9726480 SPAP_0464 Streptococcus pneumoniae AP200 threonine dehydratase YP_003876059.1 430322 D 574093 CDS YP_003876060.1 307067094 9726481 432443..432658 1 NC_014494.1 Operon 201 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 432658 9726481 SPAP_0465 Streptococcus pneumoniae AP200 hypothetical protein YP_003876060.1 432443 D 574093 CDS YP_003876061.1 307067095 9726482 complement(432767..433507) 1 NC_014494.1 Operon 202 Gene 1 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase 433507 9726482 SPAP_0466 Streptococcus pneumoniae AP200 polar amino acid ABC transporter ATPase YP_003876061.1 432767 R 574093 CDS YP_003876062.1 307067096 9726483 complement(433507..435072) 1 NC_014494.1 Operon 202 Gene 2 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 435072 9726483 SPAP_0467 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003876062.1 433507 R 574093 CDS YP_003876063.1 307067097 9726484 435210..437099 1 NC_014494.1 Operon 203 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 437099 9726484 SPAP_0468 Streptococcus pneumoniae AP200 hypothetical protein YP_003876063.1 435210 D 574093 CDS YP_003876064.1 307067098 9726485 complement(437590..438210) 1 NC_014494.1 Operon 204 Gene 1 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 438210 9726485 SPAP_0469 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_1 YP_003876064.1 437590 R 574093 CDS YP_003876065.1 307067099 9726486 complement(438128..438421) 1 NC_014494.1 Operon 204 Gene 2 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 438421 9726486 SPAP_0470 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_1 YP_003876065.1 438128 R 574093 CDS YP_003876066.1 307067100 9726487 438676..439521 1 NC_014494.1 Operon 205 Gene 1 COG1968 Uncharacterized bacitracin resistance protein; hypothetical protein 439521 9726487 SPAP_0471 Streptococcus pneumoniae AP200 hypothetical protein YP_003876066.1 438676 D 574093 CDS YP_003876067.1 307067101 9726488 complement(439668..440729) 1 NC_014494.1 Operon 206 Gene 1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; nucleotidyltransferase/DnA polymerase involved in DnA repair 440729 9726488 SPAP_0472 Streptococcus pneumoniae AP200 nucleotidyltransferase/DnA polymerase involved in DnA repair YP_003876067.1 439668 R 574093 CDS YP_003876068.1 307067102 9726489 441077..443401 1 NC_014494.1 Operon 207 Gene 1 COG1882 Pyruvate-formate lyase; pyruvate-formate lyase 443401 9726489 SPAP_0473 Streptococcus pneumoniae AP200 pyruvate-formate lyase YP_003876068.1 441077 D 574093 CDS YP_003876069.1 307067103 9726490 complement(443768..443983) 1 NC_014494.1 Operon 208 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 443983 9726490 SPAP_0474 Streptococcus pneumoniae AP200 hypothetical protein YP_003876069.1 443768 R 574093 CDS YP_003876070.1 307067104 9726491 complement(444313..444597) 1 NC_014494.1 Operon 209 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 444597 9726491 SPAP_0475 Streptococcus pneumoniae AP200 hypothetical protein YP_003876070.1 444313 R 574093 CDS YP_003876071.1 307067105 9726492 complement(445209..445379) 1 NC_014494.1 Operon 210 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 445379 9726492 SPAP_0476 Streptococcus pneumoniae AP200 hypothetical protein YP_003876071.1 445209 R 574093 CDS YP_003876072.1 307067106 9726493 complement(446029..447252) 1 NC_014494.1 Operon 211 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 447252 9726493 SPAP_0477 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003876072.1 446029 R 574093 CDS YP_003876073.1 307067107 9726494 447420..448742 1 NC_014494.1 Operon 212 Gene 1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 448742 9726494 SPAP_0478 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003876073.1 447420 D 574093 CDS YP_003876074.1 307067108 9726495 448744..449217 1 NC_014494.1 Operon 212 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 449217 9726495 SPAP_0479 Streptococcus pneumoniae AP200 hypothetical protein YP_003876074.1 448744 D 574093 CDS YP_003876075.1 307067109 9726496 449235..450632 1 NC_014494.1 Operon 212 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 450632 9726496 SPAP_0480 Streptococcus pneumoniae AP200 hypothetical protein YP_003876075.1 449235 D 574093 CDS YP_003876076.1 307067110 9726497 450800..451144 1 NC_014494.1 Operon 213 Gene 1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 451144 9726497 SPAP_0481 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIA YP_003876076.1 450800 D 574093 CDS YP_003876077.1 307067111 9726498 451154..452566 1 NC_014494.1 Operon 213 Gene 2 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 452566 9726498 SPAP_0482 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003876077.1 451154 D 574093 CDS YP_003876078.1 307067112 9726499 452636..454312 1 NC_014494.1 Operon 213 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 454312 9726499 SPAP_0483 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003876078.1 452636 D 574093 CDS YP_003876079.1 307067113 9726500 complement(454438..455865) 1 NC_014494.1 Operon 214 Gene 1 COG0168 Trk-type K+ transport systems, membrane components; Trk-type K+ transport systems membrane protein 455865 9726500 SPAP_0484 Streptococcus pneumoniae AP200 Trk-type K+ transport systems membrane protein YP_003876079.1 454438 R 574093 CDS YP_003876080.1 307067114 9726501 complement(455881..457230) 1 NC_014494.1 Operon 214 Gene 2 COG0569 K+ transport systems, NAD-binding component; K+ transport systems NAD-binding component 457230 9726501 SPAP_0485 Streptococcus pneumoniae AP200 K+ transport systems NAD-binding component YP_003876080.1 455881 R 574093 CDS YP_003876081.1 307067115 9726502 457419..458267 1 NC_014494.1 Operon 215 Gene 1 COG1912 Uncharacterized conserved protein; hypothetical protein 458267 9726502 SPAP_0486 Streptococcus pneumoniae AP200 hypothetical protein YP_003876081.1 457419 D 574093 CDS YP_003876082.1 307067116 9726503 458282..458830 1 NC_014494.1 Operon 215 Gene 2 COG4720 Predicted membrane protein; hypothetical protein 458830 9726503 SPAP_0487 Streptococcus pneumoniae AP200 hypothetical protein YP_003876082.1 458282 D 574093 CDS YP_003876083.1 307067117 9726504 458837..459049 1 NC_014494.1 Operon 215 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 459049 9726504 SPAP_0488 Streptococcus pneumoniae AP200 hypothetical protein YP_003876083.1 458837 D 574093 CDS YP_003876084.1 307067118 9726505 459151..460833 1 NC_014494.1 Operon 216 Gene 1 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 460833 9726505 SPAP_0489 Streptococcus pneumoniae AP200 cobalt ABC transporter ATPase YP_003876084.1 459151 D 574093 CDS YP_003876085.1 307067119 9726506 460818..461648 1 NC_014494.1 Operon 216 Gene 2 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter 461648 9726506 SPAP_0490 Streptococcus pneumoniae AP200 cobalt ABC transporter permease CbiQ-like transporter YP_003876085.1 460818 D 574093 CDS YP_003876086.1 307067120 9726507 461841..462344 1 NC_014494.1 Operon 217 Gene 1 COG0219 Predicted rRNA methylase (SpoU class); putative rRNA methylase 462344 9726507 SPAP_0491 Streptococcus pneumoniae AP200 putative rRNA methylase YP_003876086.1 461841 D 574093 CDS YP_003876087.1 307067121 9726508 462797..463360 1 NC_014494.1 Operon 218 Gene 1 COG3601 Predicted membrane protein; hypothetical protein 463360 9726508 SPAP_0492 Streptococcus pneumoniae AP200 hypothetical protein YP_003876087.1 462797 D 574093 CDS YP_003876088.1 307067122 9726509 463374..464000 1 NC_014494.1 Operon 218 Gene 2 COG0671 Membrane-associated phospholipid phosphatase; membrane-associated phospholipid phosphatase 464000 9726509 SPAP_0493 Streptococcus pneumoniae AP200 membrane-associated phospholipid phosphatase YP_003876088.1 463374 D 574093 CDS YP_003876089.1 307067123 9726510 464028..464417 1 NC_014494.1 Operon 218 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 464417 9726510 SPAP_0494 Streptococcus pneumoniae AP200 hypothetical protein YP_003876089.1 464028 D 574093 CDS YP_003876090.1 307067124 9726511 464422..464871 1 NC_014494.1 Operon 218 Gene 4 COG1247 Sortase and related acyltransferases; sortase-like acyltransferase 464871 9726511 SPAP_0495 Streptococcus pneumoniae AP200 sortase-like acyltransferase YP_003876090.1 464422 D 574093 CDS YP_003876091.1 307067125 9726512 464999..465586 1 NC_014494.1 Operon 219 Gene 1 COG3343 DNA-directed RNA polymerase, delta subunit; DNA-directed RNA polymerase subunit delta 465586 9726512 SPAP_0496 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase subunit delta YP_003876091.1 464999 D 574093 CDS YP_003876092.1 307067126 9726513 465976..467583 1 NC_014494.1 Operon 220 Gene 1 COG0504 CTP synthase (UTP-ammonia lyase); CTP synthase 467583 9726513 SPAP_0497 Streptococcus pneumoniae AP200 CTP synthase YP_003876092.1 465976 D 574093 CDS YP_003876093.1 307067127 9726514 complement(468142..469773) 1 NC_014494.1 Operon 221 Gene 1 COG1283 Na+/phosphate symporter; Na+/phosphate symporter 469773 9726514 SPAP_0498 Streptococcus pneumoniae AP200 Na+/phosphate symporter YP_003876093.1 468142 R 574093 CDS YP_003876094.1 307067128 9726515 469975..470085 1 NC_014494.1 Operon 222 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 470085 9726515 SPAP_0499 Streptococcus pneumoniae AP200 hypothetical protein YP_003876094.1 469975 D 574093 CDS YP_003876095.1 307067129 9726516 470066..475006 1 NC_014494.1 Operon 222 Gene 2 COG4724 Endo-beta-N-acetylglucosaminidase D; endo-beta-N-acetylglucosaminidase D 475006 9726516 SPAP_0500 Streptococcus pneumoniae AP200 endo-beta-N-acetylglucosaminidase D YP_003876095.1 470066 D 574093 CDS YP_003876096.1 307067130 9726517 475096..476292 1 NC_014494.1 Operon 222 Gene 3 COG0126 3-phosphoglycerate kinase; 3-phosphoglycerate kinase 476292 9726517 SPAP_0501 Streptococcus pneumoniae AP200 3-phosphoglycerate kinase YP_003876096.1 475096 D 574093 CDS YP_003876097.1 307067131 9726518 476428..476955 1 NC_014494.1 Operon 223 Gene 1 COG4129 Predicted membrane protein; hypothetical protein 476955 9726518 SPAP_0502 Streptococcus pneumoniae AP200 hypothetical protein YP_003876097.1 476428 D 574093 CDS YP_003876098.1 307067132 9726519 477032..477388 1 NC_014494.1 Operon 223 Gene 2 COG0789 Predicted transcriptional regulators; putative transcriptional regulator 477388 9726519 SPAP_0503 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876098.1 477032 D 574093 CDS YP_003876099.1 307067133 9726520 477425..478771 1 NC_014494.1 Operon 223 Gene 3 COG0174 Glutamine synthetase; glutamine synthetase 478771 9726520 SPAP_0504 Streptococcus pneumoniae AP200 glutamine synthetase YP_003876099.1 477425 D 574093 CDS YP_003876100.1 307067134 9726521 478951..479100 1 NC_014494.1 Operon 224 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 479100 9726521 SPAP_0505 Streptococcus pneumoniae AP200 hypothetical protein YP_003876100.1 478951 D 574093 CDS YP_003876101.1 307067135 9726522 479800..480693 1 NC_014494.1 Operon 225 Gene 1 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 480693 9726522 SPAP_0506 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876101.1 479800 D 574093 CDS YP_003876102.1 307067136 9726523 complement(480789..481295) 1 NC_014494.1 Operon 226 Gene 1 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 481295 9726523 SPAP_0507 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876102.1 480789 R 574093 CDS YP_003876103.1 307067137 9726524 complement(481405..482202) 1 NC_014494.1 Operon 227 Gene 1 COG0582 Integrase; integrase 482202 9726524 SPAP_0508 Streptococcus pneumoniae AP200 integrase YP_003876103.1 481405 R 574093 CDS YP_003876104.1 307067138 9726525 complement(482259..482981) 1 NC_014494.1 Operon 227 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 482981 9726525 SPAP_0509 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876104.1 482259 R 574093 CDS YP_003876105.1 307067139 9726526 complement(483077..483826) 1 NC_014494.1 Operon 227 Gene 3 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 483826 9726526 SPAP_0510 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876105.1 483077 R 574093 CDS YP_003876106.1 307067140 9726527 complement(483826..485289) 1 NC_014494.1 Operon 227 Gene 4 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit 485289 9726527 SPAP_0511 Streptococcus pneumoniae AP200 type I restriction-modification system methyltransferase subunit YP_003876106.1 483826 R 574093 CDS YP_003876107.1 307067141 9726528 complement(485302..487635) 1 NC_014494.1 Operon 227 Gene 5 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I site-specific restriction-modification system protein R 487635 9726528 SPAP_0512 Streptococcus pneumoniae AP200 type I site-specific restriction-modification system protein R YP_003876107.1 485302 R 574093 CDS YP_003876108.1 307067142 9726529 488242..488751 1 NC_014494.1 Operon 228 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 488751 9726529 SPAP_0513 Streptococcus pneumoniae AP200 hypothetical protein YP_003876108.1 488242 D 574093 CDS YP_003876109.1 307067143 9726530 488915..489949 1 NC_014494.1 Operon 229 Gene 1 COG1420 Transcriptional regulator of heat shock gene; heat shock proteins transcriptional regulator 489949 9726530 SPAP_0514 Streptococcus pneumoniae AP200 heat shock proteins transcriptional regulator YP_003876109.1 488915 D 574093 CDS YP_003876110.1 307067144 9726531 489976..490500 1 NC_014494.1 Operon 229 Gene 2 COG0576 Molecular chaperone GrpE (heat shock protein); molecular chaperone GrpE 490500 9726531 SPAP_0515 Streptococcus pneumoniae AP200 molecular chaperone GrpE YP_003876110.1 489976 D 574093 CDS YP_003876111.1 307067145 9726532 490980..492803 1 NC_014494.1 Operon 229 Gene 3 COG0443 Molecular chaperone; molecular chaperone 492803 9726532 SPAP_0516 Streptococcus pneumoniae AP200 molecular chaperone YP_003876111.1 490980 D 574093 CDS YP_003876112.1 307067146 9726533 493562..494698 1 NC_014494.1 Operon 230 Gene 1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; DnaJ-class molecular chaperone with C-terminal Zn finger domain 494698 9726533 SPAP_0517 Streptococcus pneumoniae AP200 DnaJ-class molecular chaperone with C-terminal Zn finger domain YP_003876112.1 493562 D 574093 CDS YP_003876113.1 307067147 9726534 complement(494727..494903) 1 NC_014494.1 Operon 231 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 494903 9726534 SPAP_0518 Streptococcus pneumoniae AP200 hypothetical protein YP_003876113.1 494727 R 574093 CDS YP_003876114.1 307067148 9726535 complement(495065..495352) 1 NC_014494.1 Operon 232 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 495352 9726535 SPAP_0519 Streptococcus pneumoniae AP200 hypothetical protein YP_003876114.1 495065 R 574093 CDS YP_003876115.1 307067149 9726536 complement(495362..495772) 1 NC_014494.1 Operon 232 Gene 2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase 495772 9726536 SPAP_0520 Streptococcus pneumoniae AP200 diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase YP_003876115.1 495362 R 574093 CDS YP_003876116.1 307067150 9726537 495840..496571 1 NC_014494.1 Operon 233 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 496571 9726537 SPAP_0521 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003876116.1 495840 D 574093 CDS YP_003876117.1 307067151 9726538 496568..497617 1 NC_014494.1 Operon 233 Gene 2 COG4473 Predicted ABC-type exoprotein transport system, permease component; putative exoprotein ABC transporter permease 497617 9726538 SPAP_0522 Streptococcus pneumoniae AP200 putative exoprotein ABC transporter permease YP_003876117.1 496568 D 574093 CDS YP_003876118.1 307067152 9726539 complement(497785..498114) 1 NC_014494.1 Operon 234 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 498114 9726539 SPAP_0523 Streptococcus pneumoniae AP200 hypothetical protein YP_003876118.1 497785 R 574093 CDS YP_003876119.1 307067153 9726540 498391..498729 1 NC_014494.1 Operon 235 Gene 1 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 498729 9726540 SPAP_0524 Streptococcus pneumoniae AP200 LytR/AlgR family response regulator YP_003876119.1 498391 D 574093 CDS YP_003876120.1 307067154 9726541 498734..499471 1 NC_014494.1 Operon 235 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 499471 9726541 SPAP_0525 Streptococcus pneumoniae AP200 LytR/AlgR family response regulator YP_003876120.1 498734 D 574093 CDS YP_003876121.1 307067155 9726542 499485..500825 1 NC_014494.1 Operon 235 Gene 3 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 500825 9726542 SPAP_0526 Streptococcus pneumoniae AP200 putative signal transduction protein YP_003876121.1 499485 D 574093 CDS YP_003876122.1 307067156 9726543 complement(500869..501024) 1 NC_014494.1 Operon 236 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 501024 9726543 SPAP_0527 Streptococcus pneumoniae AP200 hypothetical protein YP_003876122.1 500869 R 574093 CDS YP_003876123.1 307067157 9726544 complement(501081..502442) 1 NC_014494.1 Operon 236 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 502442 9726544 SPAP_0528 Streptococcus pneumoniae AP200 hypothetical protein YP_003876123.1 501081 R 574093 CDS YP_003876124.1 307067158 9726545 complement(502453..504606) 1 NC_014494.1 Operon 236 Gene 3 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter 504606 9726545 SPAP_0529 Streptococcus pneumoniae AP200 bacteriocin/lantibiotic ABC exporter YP_003876124.1 502453 R 574093 CDS YP_003876125.1 307067159 9726546 504888..505142 1 NC_014494.1 Operon 237 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 505142 9726546 SPAP_0530 Streptococcus pneumoniae AP200 hypothetical protein YP_003876125.1 504888 D 574093 CDS YP_003876126.1 307067160 9726547 505158..505361 1 NC_014494.1 Operon 237 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 505361 9726547 SPAP_0531 Streptococcus pneumoniae AP200 hypothetical protein YP_003876126.1 505158 D 574093 CDS YP_003876127.1 307067161 9726548 505380..505589 1 NC_014494.1 Operon 237 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 505589 9726548 SPAP_0532 Streptococcus pneumoniae AP200 hypothetical protein YP_003876127.1 505380 D 574093 CDS YP_003876128.1 307067162 9726549 505605..505754 1 NC_014494.1 Operon 237 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 505754 9726549 SPAP_0533 Streptococcus pneumoniae AP200 hypothetical protein YP_003876128.1 505605 D 574093 CDS YP_003876129.1 307067163 9726550 506274..506435 1 NC_014494.1 Operon 238 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 506435 9726550 SPAP_0534 Streptococcus pneumoniae AP200 hypothetical protein YP_003876129.1 506274 D 574093 CDS YP_003876130.1 307067164 9726551 506445..506816 1 NC_014494.1 Operon 238 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 506816 9726551 SPAP_0535 Streptococcus pneumoniae AP200 hypothetical protein YP_003876130.1 506445 D 574093 CDS YP_003876131.1 307067165 9726552 complement(506939..507142) 1 NC_014494.1 Operon 239 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 507142 9726552 SPAP_0536 Streptococcus pneumoniae AP200 hypothetical protein YP_003876131.1 506939 R 574093 CDS YP_003876132.1 307067166 9726553 507178..507345 1 NC_014494.1 Operon 240 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 507345 9726553 SPAP_0537 Streptococcus pneumoniae AP200 hypothetical protein YP_003876132.1 507178 D 574093 CDS YP_003876133.1 307067167 9726554 507445..507828 1 NC_014494.1 Operon 240 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 507828 9726554 SPAP_0538 Streptococcus pneumoniae AP200 hypothetical protein YP_003876133.1 507445 D 574093 CDS YP_003876134.1 307067168 9726555 507880..508569 1 NC_014494.1 Operon 240 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 508569 9726555 SPAP_0539 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876134.1 507880 D 574093 CDS YP_003876135.1 307067169 9726556 508611..508859 1 NC_014494.1 Operon 240 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 508859 9726556 SPAP_0540 Streptococcus pneumoniae AP200 hypothetical protein YP_003876135.1 508611 D 574093 CDS YP_003876136.1 307067170 9726557 508889..509500 1 NC_014494.1 Operon 240 Gene 5 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 509500 9726557 SPAP_0541 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876136.1 508889 D 574093 CDS YP_003876137.1 307067171 9726558 509662..510456 1 NC_014494.1 Operon 241 Gene 1 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative choline kinase 510456 9726558 SPAP_0542 Streptococcus pneumoniae AP200 putative choline kinase YP_003876137.1 509662 D 574093 CDS YP_003876138.1 307067172 9726559 510453..511088 1 NC_014494.1 Operon 241 Gene 2 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; putative S-adenosylmethionine-dependent methyltransferase 511088 9726559 SPAP_0543 Streptococcus pneumoniae AP200 putative S-adenosylmethionine-dependent methyltransferase YP_003876138.1 510453 D 574093 CDS YP_003876139.1 307067173 9726560 511289..511693 1 NC_014494.1 Operon 242 Gene 1 COG0779 Uncharacterized protein conserved in bacteria; hypothetical protein 511693 9726560 SPAP_0544 Streptococcus pneumoniae AP200 hypothetical protein YP_003876139.1 511289 D 574093 CDS YP_003876140.1 307067174 9726561 511749..512873 1 NC_014494.1 Operon 242 Gene 2 COG0195 Transcription elongation factor; transcription elongation factor 512873 9726561 SPAP_0545 Streptococcus pneumoniae AP200 transcription elongation factor YP_003876140.1 511749 D 574093 CDS YP_003876141.1 307067175 9726562 512895..513188 1 NC_014494.1 Operon 242 Gene 3 COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; putative nucleic-acid-binding protein implicated in transcription termination 513188 9726562 SPAP_0546 Streptococcus pneumoniae AP200 putative nucleic-acid-binding protein implicated in transcription termination YP_003876141.1 512895 D 574093 CDS YP_003876142.1 307067176 9726563 513181..513480 1 NC_014494.1 Operon 242 Gene 4 protein supported gi|15900467|ref|NP_345071.1| hypothetical protein SP_0555; hypothetical protein 513480 9726563 SPAP_0547 Streptococcus pneumoniae AP200 hypothetical protein YP_003876142.1 513181 D 574093 CDS YP_003876143.1 307067177 9726564 513497..516289 1 NC_014494.1 Operon 242 Gene 5 COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor 2 516289 9726564 SPAP_0548 Streptococcus pneumoniae AP200 translation initiation factor 2 YP_003876143.1 513497 D 574093 CDS YP_003876144.1 307067178 9726565 516540..516890 1 NC_014494.1 Operon 242 Gene 6 COG0858 Ribosome-binding factor A; ribosome-binding factor A 516890 9726565 SPAP_0549 Streptococcus pneumoniae AP200 ribosome-binding factor A YP_003876144.1 516540 D 574093 CDS YP_003876145.1 307067179 9726566 517169..517948 1 NC_014494.1 Operon 243 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 517948 9726566 SPAP_0550 Streptococcus pneumoniae AP200 hypothetical protein YP_003876145.1 517169 D 574093 CDS YP_003876146.1 307067180 9726567 517950..518132 1 NC_014494.1 Operon 243 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 518132 9726567 SPAP_0551 Streptococcus pneumoniae AP200 hypothetical protein YP_003876146.1 517950 D 574093 CDS YP_003876147.1 307067181 9726568 518637..518870 1 NC_014494.1 Operon 244 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 518870 9726568 SPAP_0552 Streptococcus pneumoniae AP200 hypothetical protein YP_003876147.1 518637 D 574093 CDS YP_003876148.1 307067182 9726569 518870..520204 1 NC_014494.1 Operon 244 Gene 2 COG2461 Uncharacterized conserved protein; hypothetical protein 520204 9726569 SPAP_0553 Streptococcus pneumoniae AP200 hypothetical protein YP_003876148.1 518870 D 574093 CDS YP_003876149.1 307067183 9726570 520214..520468 1 NC_014494.1 Operon 244 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 520468 9726570 SPAP_0554 Streptococcus pneumoniae AP200 hypothetical protein YP_003876149.1 520214 D 574093 CDS YP_003876150.1 307067184 9726571 520564..520959 1 NC_014494.1 Operon 244 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 520959 9726571 SPAP_0555 Streptococcus pneumoniae AP200 hypothetical protein YP_003876150.1 520564 D 574093 CDS YP_003876151.1 307067185 9726572 521371..521820 1 NC_014494.1 Operon 245 Gene 1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 521820 9726572 SPAP_0556 Streptococcus pneumoniae AP200 hypothetical protein YP_003876151.1 521371 D 574093 CDS YP_003876152.1 307067186 9726573 521807..522367 1 NC_014494.1 Operon 245 Gene 2 protein supported gi|125718620|ref|YP_001035753.1| ribosomal protein N-acetylase; hypothetical protein 522367 9726573 SPAP_0557 Streptococcus pneumoniae AP200 hypothetical protein YP_003876152.1 521807 D 574093 CDS YP_003876153.1 307067187 9726574 522367..522945 1 NC_014494.1 Operon 245 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 522945 9726574 SPAP_0558 Streptococcus pneumoniae AP200 hypothetical protein YP_003876153.1 522367 D 574093 CDS YP_003876154.1 307067188 9726575 522938..525589 1 NC_014494.1 Operon 245 Gene 4 COG0525 Valyl-tRNA synthetase; Valyl-tRNA synthetase 525589 9726575 SPAP_0559 Streptococcus pneumoniae AP200 Valyl-tRNA synthetase YP_003876154.1 522938 D 574093 CDS YP_003876155.1 307067189 9726576 525660..526415 1 NC_014494.1 Operon 245 Gene 5 COG5048 FOG: Zn-finger; Zn-finger 526415 9726576 SPAP_0560 Streptococcus pneumoniae AP200 Zn-finger YP_003876155.1 525660 D 574093 CDS YP_003876156.1 307067190 9726577 526700..526801 1 NC_014494.1 Operon 246 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 526801 9726577 SPAP_0561 Streptococcus pneumoniae AP200 hypothetical protein YP_003876156.1 526700 D 574093 CDS YP_003876157.1 307067191 9726578 526925..527794 1 NC_014494.1 Operon 247 Gene 1 COG4951 Uncharacterized protein conserved in bacteria; hypothetical protein 527794 9726578 SPAP_0562 Streptococcus pneumoniae AP200 hypothetical protein YP_003876157.1 526925 D 574093 CDS YP_003876158.1 307067192 9726579 complement(527808..528185) 1 NC_014494.1 Operon 248 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 528185 9726579 SPAP_0563 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876158.1 527808 R 574093 CDS YP_003876159.1 307067193 9726580 complement(528198..528623) 1 NC_014494.1 transposase-like protein, IS1515 528623 9726580 SPAP_0564 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876159.1 528198 R 574093 CDS YP_003876160.1 307067194 9726581 528798..528944 1 NC_014494.1 Operon 249 Gene 1 COG1061 DNA or RNA helicases of superfamily II; DNA or RNA helicases of superfamily II 528944 9726581 SPAP_0565 Streptococcus pneumoniae AP200 DNA or RNA helicases of superfamily II YP_003876160.1 528798 D 574093 CDS YP_003876161.1 307067195 9726582 529040..530356 1 NC_014494.1 Operon 249 Gene 2 COG1061 DNA or RNA helicases of superfamily II; DNA or RNA helicases of superfamily II 530356 9726582 SPAP_0566 Streptococcus pneumoniae AP200 DNA or RNA helicases of superfamily II YP_003876161.1 529040 D 574093 CDS YP_003876162.1 307067196 9726583 530656..531495 1 NC_014494.1 Operon 250 Gene 1 COG3711 Transcriptional antiterminator; transcriptional antiterminator 531495 9726583 SPAP_0567 Streptococcus pneumoniae AP200 transcriptional antiterminator YP_003876162.1 530656 D 574093 CDS YP_003876163.1 307067197 9726584 531513..533351 1 NC_014494.1 Operon 250 Gene 2 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 533351 9726584 SPAP_0568 Streptococcus pneumoniae AP200 PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC YP_003876163.1 531513 D 574093 CDS YP_003876164.1 307067198 9726585 533364..534779 1 NC_014494.1 Operon 250 Gene 3 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 534779 9726585 SPAP_0569 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003876164.1 533364 D 574093 CDS YP_003876165.1 307067199 9726586 535325..536413 1 NC_014494.1 Operon 251 Gene 1 COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 536413 9726586 SPAP_0570 Streptococcus pneumoniae AP200 phenylalanyl-tRNA synthetase subunit alpha YP_003876165.1 535325 D 574093 CDS YP_003876166.1 307067200 9726587 536413..536922 1 NC_014494.1 Operon 251 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 536922 9726587 SPAP_0571 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003876166.1 536413 D 574093 CDS YP_003876167.1 307067201 9726588 536999..539404 1 NC_014494.1 Operon 251 Gene 3 COG0072 Phenylalanyl-tRNA synthetase beta subunit; phenylalanyl-tRNA synthetase subunit beta 539404 9726588 SPAP_0572 Streptococcus pneumoniae AP200 phenylalanyl-tRNA synthetase subunit beta YP_003876167.1 536999 D 574093 CDS YP_003876168.1 307067202 9726589 complement(539472..540473) 1 NC_014494.1 Operon 252 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 540473 9726589 SPAP_0573 Streptococcus pneumoniae AP200 hypothetical protein YP_003876168.1 539472 R 574093 CDS YP_003876169.1 307067203 9726590 540629..540853 1 NC_014494.1 transposase-like protein, IS1239 540853 9726590 SPAP_0574 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876169.1 540629 D 574093 CDS YP_003876170.1 307067204 9726591 540907..541035 1 NC_014494.1 Operon 253 Gene 2 COG2826 Transposase and inactivated derivatives, IS30 family; transposase-like protein, IS30 family 541035 9726591 SPAP_0575 Streptococcus pneumoniae AP200 transposase-like protein, IS30 family YP_003876170.1 540907 D 574093 CDS YP_003876171.1 307067205 9726592 541227..541424 1 NC_014494.1 Operon 254 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 541424 9726592 SPAP_0576 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876171.1 541227 D 574093 CDS YP_003876172.1 307067206 9726593 541685..543934 1 NC_014494.1 Operon 255 Gene 1 COG0620 Methionine synthase II (cobalamin-independent); methionine synthase II 543934 9726593 SPAP_0577 Streptococcus pneumoniae AP200 methionine synthase II YP_003876172.1 541685 D 574093 CDS YP_003876173.1 307067207 9726594 543998..544864 1 NC_014494.1 Operon 255 Gene 2 COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 544864 9726594 SPAP_0578 Streptococcus pneumoniae AP200 5,10-methylenetetrahydrofolate reductase YP_003876173.1 543998 D 574093 CDS YP_003876174.1 307067208 9726595 545549..547762 1 NC_014494.1 Operon 256 Gene 1 protein supported gi|62291006|ref|YP_222799.1| polynucleotide phosphorylase/polyadenylase; hypothetical protein 547762 9726595 SPAP_0579 Streptococcus pneumoniae AP200 hypothetical protein YP_003876174.1 545549 D 574093 CDS YP_003876175.1 307067209 9726596 547778..548395 1 NC_014494.1 Operon 256 Gene 2 COG1045 Serine acetyltransferase; serine acetyltransferase 548395 9726596 SPAP_0580 Streptococcus pneumoniae AP200 serine acetyltransferase YP_003876175.1 547778 D 574093 CDS YP_003876176.1 307067210 9726597 548407..549291 1 NC_014494.1 Operon 256 Gene 3 COG0456 Acetyltransferases; acetyltransferase 549291 9726597 SPAP_0581 Streptococcus pneumoniae AP200 acetyltransferase YP_003876176.1 548407 D 574093 CDS YP_003876177.1 307067211 9726598 549394..550716 1 NC_014494.1 Operon 257 Gene 1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 550716 9726598 SPAP_0582 Streptococcus pneumoniae AP200 cysteinyl-tRNA synthetase YP_003876177.1 549394 D 574093 CDS YP_003876178.1 307067212 9726599 550709..551095 1 NC_014494.1 Operon 257 Gene 2 protein supported gi|163764762|ref|ZP_02171816.1| ribosomal protein S13; hypothetical protein 551095 9726599 SPAP_0583 Streptococcus pneumoniae AP200 hypothetical protein YP_003876178.1 550709 D 574093 CDS YP_003876179.1 307067213 9726600 551099..551983 1 NC_014494.1 Operon 257 Gene 3 COG2508 Regulator of polyketide synthase expression; Regulator of polyketide synthase expression 551983 9726600 SPAP_0584 Streptococcus pneumoniae AP200 Regulator of polyketide synthase expression YP_003876179.1 551099 D 574093 CDS YP_003876180.1 307067214 9726601 552225..552824 1 NC_014494.1 Operon 258 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 552824 9726601 SPAP_0585 Streptococcus pneumoniae AP200 hypothetical protein YP_003876180.1 552225 D 574093 CDS YP_003876181.1 307067215 9726602 552970..553143 1 NC_014494.1 Operon 259 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 553143 9726602 SPAP_0586 Streptococcus pneumoniae AP200 hypothetical protein YP_003876181.1 552970 D 574093 CDS YP_003876182.1 307067216 9726603 553494..554771 1 NC_014494.1 Operon 260 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 554771 9726603 SPAP_0587 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003876182.1 553494 D 574093 CDS YP_003876183.1 307067217 9726604 554784..555431 1 NC_014494.1 Operon 260 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 555431 9726604 SPAP_0588 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876183.1 554784 D 574093 CDS YP_003876184.1 307067218 9726605 555483..556862 1 NC_014494.1 Operon 260 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 556862 9726605 SPAP_0589 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003876184.1 555483 D 574093 CDS YP_003876185.1 307067219 9726606 557174..557830 1 NC_014494.1 Operon 261 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 557830 9726606 SPAP_0590 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003876185.1 557174 D 574093 CDS YP_003876186.1 307067220 9726607 557827..559155 1 NC_014494.1 Operon 261 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 559155 9726607 SPAP_0591 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003876186.1 557827 D 574093 CDS YP_003876187.1 307067221 9726608 559296..560177 1 NC_014494.1 Operon 262 Gene 1 COG0191 Fructose/tagatose bisphosphate aldolase; fructose/tagatose bisphosphate aldolase 560177 9726608 SPAP_0592 Streptococcus pneumoniae AP200 fructose/tagatose bisphosphate aldolase YP_003876187.1 559296 D 574093 CDS YP_003876188.1 307067222 9726609 complement(560498..561688) 1 NC_014494.1 Operon 263 Gene 1 COG4097 Predicted ferric reductase; putative ferric reductase 561688 9726609 SPAP_0593 Streptococcus pneumoniae AP200 putative ferric reductase YP_003876188.1 560498 R 574093 CDS YP_003876189.1 307067223 9726610 complement(561946..562605) 1 NC_014494.1 Operon 264 Gene 1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 562605 9726610 SPAP_0594 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003876189.1 561946 R 574093 CDS YP_003876190.1 307067224 9726611 complement(562615..563292) 1 NC_014494.1 Operon 264 Gene 2 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 563292 9726611 SPAP_0595 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003876190.1 562615 R 574093 CDS YP_003876191.1 307067225 9726612 complement(563305..564099) 1 NC_014494.1 Operon 264 Gene 3 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 564099 9726612 SPAP_0596 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003876191.1 563305 R 574093 CDS YP_003876192.1 307067226 9726613 complement(564110..564868) 1 NC_014494.1 Operon 264 Gene 4 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase 564868 9726613 SPAP_0597 Streptococcus pneumoniae AP200 polar amino acid ABC transporter ATPase YP_003876192.1 564110 R 574093 CDS YP_003876193.1 307067227 9726614 565133..567367 1 NC_014494.1 Operon 265 Gene 1 COG0608 Single-stranded DNA-specific exonuclease; single-stranded DNA-specific exonuclease 567367 9726614 SPAP_0598 Streptococcus pneumoniae AP200 single-stranded DNA-specific exonuclease YP_003876193.1 565133 D 574093 CDS YP_003876194.1 307067228 9726615 567542..569203 1 NC_014494.1 Operon 266 Gene 1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; putative metallo-beta-lactamase superfamily hydrolase 569203 9726615 SPAP_0599 Streptococcus pneumoniae AP200 putative metallo-beta-lactamase superfamily hydrolase YP_003876194.1 567542 D 574093 CDS YP_003876195.1 307067229 9726616 569272..570051 1 NC_014494.1 Operon 266 Gene 2 COG0627 Predicted esterase; putative esterase 570051 9726616 SPAP_0600 Streptococcus pneumoniae AP200 putative esterase YP_003876195.1 569272 D 574093 CDS YP_003876196.1 307067230 9726617 570163..571383 1 NC_014494.1 Operon 267 Gene 1 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 571383 9726617 SPAP_0601 Streptococcus pneumoniae AP200 hypothetical protein YP_003876196.1 570163 D 574093 CDS YP_003876197.1 307067231 9726618 571388..572620 1 NC_014494.1 Operon 267 Gene 2 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 572620 9726618 SPAP_0602 Streptococcus pneumoniae AP200 hypothetical protein YP_003876197.1 571388 D 574093 CDS YP_003876198.1 307067232 9726619 572699..573400 1 NC_014494.1 Operon 267 Gene 3 COG5549 Predicted Zn-dependent protease; putative Zn-dependent protease 573400 9726619 SPAP_0603 Streptococcus pneumoniae AP200 putative Zn-dependent protease YP_003876198.1 572699 D 574093 CDS YP_003876199.1 307067233 9726620 573439..575286 1 NC_014494.1 Operon 267 Gene 4 COG0322 Nuclease subunit of the excinuclease complex; nuclease subunit of the excinuclease complex 575286 9726620 SPAP_0604 Streptococcus pneumoniae AP200 nuclease subunit of the excinuclease complex YP_003876199.1 573439 D 574093 CDS YP_003876200.1 307067234 9726621 575276..576109 1 NC_014494.1 Operon 267 Gene 5 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase 576109 9726621 SPAP_0605 Streptococcus pneumoniae AP200 diadenosine tetraphosphatase-like serine/threonine protein phosphatase YP_003876200.1 575276 D 574093 CDS YP_003876201.1 307067235 9726622 complement(576291..577091) 1 NC_014494.1 Operon 268 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 577091 9726622 SPAP_0606 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003876201.1 576291 R 574093 CDS YP_003876202.1 307067236 9726623 577165..577275 1 NC_014494.1 Operon 269 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 577275 9726623 SPAP_0607 Streptococcus pneumoniae AP200 hypothetical protein YP_003876202.1 577165 D 574093 CDS YP_003876203.1 307067237 9726624 577262..577867 1 NC_014494.1 Operon 269 Gene 2 COG0778 Nitroreductase; nitroreductase 577867 9726624 SPAP_0608 Streptococcus pneumoniae AP200 nitroreductase YP_003876203.1 577262 D 574093 CDS YP_003876204.1 307067238 9726625 577880..579280 1 NC_014494.1 Operon 269 Gene 3 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 579280 9726625 SPAP_0609 Streptococcus pneumoniae AP200 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases YP_003876204.1 577880 D 574093 CDS YP_003876205.1 307067239 9726626 579334..579912 1 NC_014494.1 Operon 269 Gene 4 protein supported gi|148988990|ref|ZP_01820390.1| hypothetical protein CGSSp6BS73_02415; hypothetical protein 579912 9726626 SPAP_0610 Streptococcus pneumoniae AP200 hypothetical protein YP_003876205.1 579334 D 574093 CDS YP_003876206.1 307067240 9726627 580072..580224 1 NC_014494.1 Operon 270 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 580224 9726627 SPAP_0611 Streptococcus pneumoniae AP200 hypothetical protein YP_003876206.1 580072 D 574093 CDS YP_003876207.1 307067241 9726628 580530..581855 1 NC_014494.1 Operon 271 Gene 1 COG1114 Branched-chain amino acid permeases; branched-chain amino acid permease 581855 9726628 SPAP_0612 Streptococcus pneumoniae AP200 branched-chain amino acid permease YP_003876207.1 580530 D 574093 CDS YP_003876208.1 307067242 9726629 581953..582990 1 NC_014494.1 Operon 272 Gene 1 COG1363 Cellulase M and related proteins; cellulase M-like proteins 582990 9726629 SPAP_0613 Streptococcus pneumoniae AP200 cellulase M-like proteins YP_003876208.1 581953 D 574093 CDS YP_003876209.1 307067243 9726630 582992..583453 1 NC_014494.1 Operon 272 Gene 2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase 583453 9726630 SPAP_0614 Streptococcus pneumoniae AP200 diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase YP_003876209.1 582992 D 574093 CDS YP_003876210.1 307067244 9726631 583479..584195 1 NC_014494.1 Operon 272 Gene 3 COG1876 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 584195 9726631 SPAP_0615 Streptococcus pneumoniae AP200 D-alanyl-D-alanine carboxypeptidase YP_003876210.1 583479 D 574093 CDS YP_003876211.1 307067245 9726632 584504..584929 1 NC_014494.1 Operon 273 Gene 1 protein supported gi|15900537|ref|NP_345141.1| 50S ribosomal protein L11; 50S ribosomal protein L11 584929 9726632 SPAP_0616 Streptococcus pneumoniae AP200 50S ribosomal protein L11 YP_003876211.1 584504 D 574093 CDS YP_003876212.1 307067246 9726633 585137..585826 1 NC_014494.1 Operon 273 Gene 2 protein supported gi|15900538|ref|NP_345142.1| 50S ribosomal protein L1; hypothetical protein 585826 9726633 SPAP_0617 Streptococcus pneumoniae AP200 hypothetical protein YP_003876212.1 585137 D 574093 CDS YP_003876213.1 307067247 9726634 complement(585915..586301) 1 NC_014494.1 Operon 274 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 586301 9726634 SPAP_0618 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876213.1 585915 R 574093 CDS YP_003876214.1 307067248 9726635 complement(586438..587220) 1 NC_014494.1 Operon 275 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 587220 9726635 SPAP_0619 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876214.1 586438 R 574093 CDS YP_003876215.1 307067249 9726636 587944..588306 1 NC_014494.1 Operon 276 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 588306 9726636 SPAP_0620 Streptococcus pneumoniae AP200 hypothetical protein YP_003876215.1 587944 D 574093 CDS YP_003876216.1 307067250 9726637 588705..588950 1 NC_014494.1 Operon 277 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 588950 9726637 SPAP_0621 Streptococcus pneumoniae AP200 hypothetical protein YP_003876216.1 588705 D 574093 CDS YP_003876217.1 307067251 9726638 complement(588878..589036) 1 NC_014494.1 Operon 278 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 589036 9726638 SPAP_0622 Streptococcus pneumoniae AP200 hypothetical protein YP_003876217.1 588878 R 574093 CDS YP_003876218.1 307067252 9726639 589351..590343 1 NC_014494.1 Operon 279 Gene 1 COG4586 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase 590343 9726639 SPAP_0623 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876218.1 589351 D 574093 CDS YP_003876219.1 307067253 9726640 590345..591163 1 NC_014494.1 Operon 279 Gene 2 COG4587 ABC-type uncharacterized transport system, permease component; ABC transporter permease 591163 9726640 SPAP_0624 Streptococcus pneumoniae AP200 ABC transporter permease YP_003876219.1 590345 D 574093 CDS YP_003876220.1 307067254 9726641 591165..591950 1 NC_014494.1 Operon 279 Gene 3 COG3694 ABC-type uncharacterized transport system, permease component; ABC transporter permease 591950 9726641 SPAP_0625 Streptococcus pneumoniae AP200 ABC transporter permease YP_003876220.1 591165 D 574093 CDS YP_003876221.1 307067255 9726642 591989..592093 1 NC_014494.1 Operon 279 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 592093 9726642 SPAP_0626 Streptococcus pneumoniae AP200 hypothetical protein YP_003876221.1 591989 D 574093 CDS YP_003876222.1 307067256 9726643 592252..592449 1 NC_014494.1 Operon 280 Gene 1 COG0456 Acetyltransferases; acetyltransferase 592449 9726643 SPAP_0627 Streptococcus pneumoniae AP200 acetyltransferase YP_003876222.1 592252 D 574093 CDS YP_003876223.1 307067257 9726644 complement(592725..592949) 1 NC_014494.1 Operon 281 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 592949 9726644 SPAP_0628 Streptococcus pneumoniae AP200 hypothetical protein YP_003876223.1 592725 R 574093 CDS YP_003876224.1 307067258 9726645 593182..593457 1 NC_014494.1 Operon 282 Gene 1 protein supported gi|148984022|ref|ZP_01817341.1| 50S ribosomal protein L1; hypothetical protein 593457 9726645 SPAP_0629 Streptococcus pneumoniae AP200 hypothetical protein YP_003876224.1 593182 D 574093 CDS YP_003876225.1 307067259 9726646 593771..599614 1 NC_014494.1 Operon 282 Gene 2 protein supported gi|148984022|ref|ZP_01817341.1| 50S ribosomal protein L1; hypothetical protein 599614 9726646 SPAP_0630 Streptococcus pneumoniae AP200 hypothetical protein YP_003876225.1 593771 D 574093 CDS YP_003876226.1 307067260 9726647 600241..600717 1 NC_014494.1 Operon 283 Gene 1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein 600717 9726647 SPAP_0631 Streptococcus pneumoniae AP200 PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein YP_003876226.1 600241 D 574093 CDS YP_003876227.1 307067261 9726648 600755..601003 1 NC_014494.1 Operon 283 Gene 2 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 601003 9726648 SPAP_0632 Streptococcus pneumoniae AP200 PTS system galactitol-specific transporter subunit IIB YP_003876227.1 600755 D 574093 CDS YP_003876228.1 307067262 9726649 601107..602582 1 NC_014494.1 Operon 283 Gene 3 COG3775 Phosphotransferase system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 602582 9726649 SPAP_0633 Streptococcus pneumoniae AP200 PTS system galactitol-specific transporter subunit IIC YP_003876228.1 601107 D 574093 CDS YP_003876229.1 307067263 9726650 602608..602799 1 NC_014494.1 Operon 283 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 602799 9726650 SPAP_0634 Streptococcus pneumoniae AP200 hypothetical protein YP_003876229.1 602608 D 574093 CDS YP_003876230.1 307067264 9726651 602887..609588 1 NC_014494.1 Operon 283 Gene 5 COG3250 Beta-galactosidase/beta-glucuronidase; beta-galactosidase/beta-glucuronidase 609588 9726651 SPAP_0635 Streptococcus pneumoniae AP200 beta-galactosidase/beta-glucuronidase YP_003876230.1 602887 D 574093 CDS YP_003876231.1 307067265 9726652 complement(609898..610452) 1 NC_014494.1 Operon 284 Gene 1 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_2 610452 9726652 SPAP_0636 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_2 YP_003876231.1 609898 R 574093 CDS YP_003876232.1 307067266 9726653 complement(610440..610685) 1 NC_014494.1 Operon 284 Gene 2 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_2 610685 9726653 SPAP_0637 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_2 YP_003876232.1 610440 R 574093 CDS YP_003876233.1 307067267 9726654 complement(610643..610846) 1 NC_014494.1 Operon 284 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 610846 9726654 SPAP_0638 Streptococcus pneumoniae AP200 hypothetical protein YP_003876233.1 610643 R 574093 CDS YP_003876234.1 307067268 9726655 complement(611024..612367) 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 612367 9726655 SPAP_0639 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876234.1 611024 R 574093 CDS YP_003876235.1 307067269 9726656 complement(612602..612946) 1 NC_014494.1 Operon 286 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 612946 9726656 SPAP_0640 Streptococcus pneumoniae AP200 hypothetical protein YP_003876235.1 612602 R 574093 CDS YP_003876236.1 307067270 9726657 613062..613562 1 NC_014494.1 Operon 287 Gene 1 COG1242 Predicted Fe-S oxidoreductase; putative Fe-S oxidoreductase 613562 9726657 SPAP_0641 Streptococcus pneumoniae AP200 putative Fe-S oxidoreductase YP_003876236.1 613062 D 574093 CDS YP_003876237.1 307067271 9726658 613563..614009 1 NC_014494.1 Operon 287 Gene 2 COG1242 Predicted Fe-S oxidoreductase; putative Fe-S oxidoreductase 614009 9726658 SPAP_0642 Streptococcus pneumoniae AP200 putative Fe-S oxidoreductase YP_003876237.1 613563 D 574093 CDS YP_003876238.1 307067272 9726659 613993..614550 1 NC_014494.1 Operon 287 Gene 3 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 614550 9726659 SPAP_0643 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003876238.1 613993 D 574093 CDS YP_003876239.1 307067273 9726660 614543..614797 1 NC_014494.1 Operon 287 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 614797 9726660 SPAP_0644 Streptococcus pneumoniae AP200 hypothetical protein YP_003876239.1 614543 D 574093 CDS YP_003876240.1 307067274 9726661 614809..616863 1 NC_014494.1 Operon 287 Gene 5 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; NhaP-type Na+/H+ and K+/H+ antiporter 616863 9726661 SPAP_0645 Streptococcus pneumoniae AP200 NhaP-type Na+/H+ and K+/H+ antiporter YP_003876240.1 614809 D 574093 CDS YP_003876241.1 307067275 9726662 617047..617907 1 NC_014494.1 Operon 288 Gene 1 COG1295 Predicted membrane protein; hypothetical protein 617907 9726662 SPAP_0646 Streptococcus pneumoniae AP200 hypothetical protein YP_003876241.1 617047 D 574093 CDS YP_003876242.1 307067276 9726663 618118..618828 1 NC_014494.1 Operon 289 Gene 1 COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 618828 9726663 SPAP_0647 Streptococcus pneumoniae AP200 cytochrome c biogenesis protein YP_003876242.1 618118 D 574093 CDS YP_003876243.1 307067277 9726664 618848..619414 1 NC_014494.1 Operon 289 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 619414 9726664 SPAP_0648 Streptococcus pneumoniae AP200 thiol-disulfide isomerase and thioredoxin YP_003876243.1 618848 D 574093 CDS YP_003876244.1 307067278 9726665 619425..620537 1 NC_014494.1 Operon 289 Gene 3 COG0225 Peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 620537 9726665 SPAP_0649 Streptococcus pneumoniae AP200 peptide methionine sulfoxide reductase YP_003876244.1 619425 D 574093 CDS YP_003876245.1 307067279 9726666 620805..621542 1 NC_014494.1 Operon 290 Gene 1 COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; CheY-like receiver/AraC DNA-binding domain-containing response regulator 621542 9726666 SPAP_0650 Streptococcus pneumoniae AP200 CheY-like receiver/AraC DNA-binding domain-containing response regulator YP_003876245.1 620805 D 574093 CDS YP_003876246.1 307067280 9726667 621539..623230 1 NC_014494.1 Operon 290 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 623230 9726667 SPAP_0651 Streptococcus pneumoniae AP200 putative signal transduction protein YP_003876246.1 621539 D 574093 CDS YP_003876247.1 307067281 9726668 623346..623909 1 NC_014494.1 Operon 291 Gene 1 COG4475 Uncharacterized protein conserved in bacteria; hypothetical protein 623909 9726668 SPAP_0652 Streptococcus pneumoniae AP200 hypothetical protein YP_003876247.1 623346 D 574093 CDS YP_003876248.1 307067282 9726669 623931..629594 1 NC_014494.1 zinc metalloprotease ZmpB; hypothetical protein 629594 9726669 SPAP_0653 Streptococcus pneumoniae AP200 hypothetical protein YP_003876248.1 623931 D 574093 CDS YP_003876249.1 307067283 9726670 629663..631384 1 NC_014494.1 Operon 292 Gene 1 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate/para-aminobenzoate synthases component I 631384 9726670 SPAP_0654 Streptococcus pneumoniae AP200 anthranilate/para-aminobenzoate synthases component I YP_003876249.1 629663 D 574093 CDS YP_003876250.1 307067284 9726671 631385..632002 1 NC_014494.1 Operon 292 Gene 2 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative alpha/beta superfamily hydrolase 632002 9726671 SPAP_0655 Streptococcus pneumoniae AP200 putative alpha/beta superfamily hydrolase YP_003876250.1 631385 D 574093 CDS YP_003876251.1 307067285 9726672 632052..633050 1 NC_014494.1 Operon 292 Gene 3 COG5263 FOG: Choline binding protein; choline binding protein 633050 9726672 SPAP_0656 Streptococcus pneumoniae AP200 choline binding protein YP_003876251.1 632052 D 574093 CDS YP_003876252.1 307067286 9726673 633177..634136 1 NC_014494.1 Operon 293 Gene 1 protein supported gi|116517028|ref|YP_816079.1| glucokinase; hypothetical protein 634136 9726673 SPAP_0657 Streptococcus pneumoniae AP200 hypothetical protein YP_003876252.1 633177 D 574093 CDS YP_003876253.1 307067287 9726674 634233..635072 1 NC_014494.1 Operon 293 Gene 2 COG0207 Thymidylate synthase; thymidylate synthase 635072 9726674 SPAP_0658 Streptococcus pneumoniae AP200 thymidylate synthase YP_003876253.1 634233 D 574093 CDS YP_003876254.1 307067288 9726675 complement(635120..635290) 1 NC_014494.1 Operon 294 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 635290 9726675 SPAP_0659 Streptococcus pneumoniae AP200 hypothetical protein YP_003876254.1 635120 R 574093 CDS YP_003876255.1 307067289 9726676 635387..636295 1 NC_014494.1 Operon 295 Gene 1 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase 636295 9726676 SPAP_0660 Streptococcus pneumoniae AP200 tRNA delta(2)-isopentenylpyrophosphate transferase YP_003876255.1 635387 D 574093 CDS YP_003876256.1 307067290 9726677 636288..637526 1 NC_014494.1 Operon 295 Gene 2 COG2262 GTPases; GTPase 637526 9726677 SPAP_0661 Streptococcus pneumoniae AP200 GTPase YP_003876256.1 636288 D 574093 CDS YP_003876257.1 307067291 9726678 637519..638142 1 NC_014494.1 Operon 295 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 638142 9726678 SPAP_0662 Streptococcus pneumoniae AP200 hypothetical protein YP_003876257.1 637519 D 574093 CDS YP_003876258.1 307067292 9726679 638157..639086 1 NC_014494.1 Operon 295 Gene 4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; metal-dependent hydrolases of the beta-lactamase superfamily III 639086 9726679 SPAP_0663 Streptococcus pneumoniae AP200 metal-dependent hydrolases of the beta-lactamase superfamily III YP_003876258.1 638157 D 574093 CDS YP_003876259.1 307067293 9726680 639107..639862 1 NC_014494.1 Operon 295 Gene 5 COG0300 Short-chain dehydrogenases of various substrate specificities; short-chain dehydrogenase of various substrate specificities 639862 9726680 SPAP_0664 Streptococcus pneumoniae AP200 short-chain dehydrogenase of various substrate specificities YP_003876259.1 639107 D 574093 CDS YP_003876260.1 307067294 9726681 complement(639916..640884) 1 NC_014494.1 Operon 296 Gene 1 COG0583 Transcriptional regulator; transcriptional regulator 640884 9726681 SPAP_0665 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876260.1 639916 R 574093 CDS YP_003876261.1 307067295 9726682 640888..641157 1 NC_014494.1 Operon 297 Gene 1 COG4483 Uncharacterized protein conserved in bacteria; hypothetical protein 641157 9726682 SPAP_0666 Streptococcus pneumoniae AP200 hypothetical protein YP_003876261.1 640888 D 574093 CDS YP_003876262.1 307067296 9726683 641157..641537 1 NC_014494.1 Operon 297 Gene 2 COG0607 Rhodanese-related sulfurtransferase; rhodanese-related sulfurtransferase 641537 9726683 SPAP_0667 Streptococcus pneumoniae AP200 rhodanese-related sulfurtransferase YP_003876262.1 641157 D 574093 CDS YP_003876263.1 307067297 9726684 641626..641853 1 NC_014494.1 Operon 297 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 641853 9726684 SPAP_0668 Streptococcus pneumoniae AP200 hypothetical protein YP_003876263.1 641626 D 574093 CDS YP_003876264.1 307067298 9726685 complement(641893..642618) 1 NC_014494.1 Operon 298 Gene 1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase 642618 9726685 SPAP_0669 Streptococcus pneumoniae AP200 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase YP_003876264.1 641893 R 574093 CDS YP_003876265.1 307067299 9726686 642780..644621 1 NC_014494.1 Operon 299 Gene 1 COG1217 Predicted membrane GTPase involved in stress response; putative membrane GTPase involved in stress response 644621 9726686 SPAP_0670 Streptococcus pneumoniae AP200 putative membrane GTPase involved in stress response YP_003876265.1 642780 D 574093 CDS YP_003876266.1 307067300 9726687 644641..644895 1 NC_014494.1 Operon 299 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 644895 9726687 SPAP_0671 Streptococcus pneumoniae AP200 hypothetical protein YP_003876266.1 644641 D 574093 CDS YP_003876267.1 307067301 9726688 645629..646669 1 NC_014494.1 Operon 300 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 646669 9726688 SPAP_0672 Streptococcus pneumoniae AP200 hypothetical protein YP_003876267.1 645629 D 574093 CDS YP_003876268.1 307067302 9726689 646844..647650 1 NC_014494.1 Operon 301 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 647650 9726689 SPAP_0673 Streptococcus pneumoniae AP200 hypothetical protein YP_003876268.1 646844 D 574093 CDS YP_003876269.1 307067303 9726690 647652..648293 1 NC_014494.1 Operon 301 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 648293 9726690 SPAP_0674 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876269.1 647652 D 574093 CDS YP_003876270.1 307067304 9726691 648397..649749 1 NC_014494.1 Operon 302 Gene 1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoylalanine-D-glutamate ligase 649749 9726691 SPAP_0675 Streptococcus pneumoniae AP200 UDP-N-acetylmuramoylalanine-D-glutamate ligase YP_003876270.1 648397 D 574093 CDS YP_003876271.1 307067305 9726692 649753..650811 1 NC_014494.1 Operon 302 Gene 2 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase 650811 9726692 SPAP_0676 Streptococcus pneumoniae AP200 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase YP_003876271.1 649753 D 574093 CDS YP_003876272.1 307067306 9726693 650821..652050 1 NC_014494.1 Operon 302 Gene 3 COG1589 Cell division septal protein; cell division septal protein 652050 9726693 SPAP_0677 Streptococcus pneumoniae AP200 cell division septal protein YP_003876272.1 650821 D 574093 CDS YP_003876273.1 307067307 9726694 652283..652984 1 NC_014494.1 Operon 303 Gene 1 COG0284 Orotidine-5'-phosphate decarboxylase; orotidine-5'-phosphate decarboxylase 652984 9726694 SPAP_0678 Streptococcus pneumoniae AP200 orotidine-5'-phosphate decarboxylase YP_003876273.1 652283 D 574093 CDS YP_003876274.1 307067308 9726695 653018..653650 1 NC_014494.1 Operon 303 Gene 2 COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 653650 9726695 SPAP_0679 Streptococcus pneumoniae AP200 orotate phosphoribosyltransferase YP_003876274.1 653018 D 574093 CDS YP_003876275.1 307067309 9726696 653883..654233 1 NC_014494.1 Operon 304 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 654233 9726696 SPAP_0680 Streptococcus pneumoniae AP200 hypothetical protein YP_003876275.1 653883 D 574093 CDS YP_003876276.1 307067310 9726697 654330..655094 1 NC_014494.1 Operon 304 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 655094 9726697 SPAP_0681 Streptococcus pneumoniae AP200 hypothetical protein YP_003876276.1 654330 D 574093 CDS YP_003876277.1 307067311 9726698 656207..656554 1 NC_014494.1 Operon 305 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 656554 9726698 SPAP_0682 Streptococcus pneumoniae AP200 hypothetical protein YP_003876277.1 656207 D 574093 CDS YP_003876278.1 307067312 9726699 656551..657198 1 NC_014494.1 Operon 305 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 657198 9726699 SPAP_0683 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003876278.1 656551 D 574093 CDS YP_003876279.1 307067313 9726700 complement(657285..658151) 1 NC_014494.1 Operon 306 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 658151 9726700 SPAP_0684 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003876279.1 657285 R 574093 CDS YP_003876280.1 307067314 9726701 complement(658163..658669) 1 NC_014494.1 Operon 306 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 658669 9726701 SPAP_0685 Streptococcus pneumoniae AP200 hypothetical protein YP_003876280.1 658163 R 574093 CDS YP_003876281.1 307067315 9726702 complement(658810..658920) 1 NC_014494.1 Operon 306 Gene 3 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase 658920 9726702 SPAP_0686 Streptococcus pneumoniae AP200 polar amino acid ABC transporter ATPase YP_003876281.1 658810 R 574093 CDS YP_003876282.1 307067316 9726703 complement(658921..659598) 1 NC_014494.1 Operon 306 Gene 4 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 659598 9726703 SPAP_0687 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003876282.1 658921 R 574093 CDS YP_003876283.1 307067317 9726704 complement(659558..660238) 1 NC_014494.1 Operon 306 Gene 5 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 660238 9726704 SPAP_0688 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003876283.1 659558 R 574093 CDS YP_003876284.1 307067318 9726705 660453..660599 1 NC_014494.1 Operon 307 Gene 1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 660599 9726705 SPAP_0689 Streptococcus pneumoniae AP200 L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase YP_003876284.1 660453 D 574093 CDS YP_003876285.1 307067319 9726706 660727..662217 1 NC_014494.1 Operon 308 Gene 1 COG1190 Lysyl-tRNA synthetase (class II); Lysyl-tRNA synthetase (class II) 662217 9726706 SPAP_0690 Streptococcus pneumoniae AP200 Lysyl-tRNA synthetase (class II) YP_003876285.1 660727 D 574093 CDS YP_003876286.1 307067320 9726707 662841..663977 1 NC_014494.1 Operon 309 Gene 1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 663977 9726707 SPAP_0691 Streptococcus pneumoniae AP200 L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase YP_003876286.1 662841 D 574093 CDS YP_003876287.1 307067321 9726708 664532..665200 1 NC_014494.1 Operon 310 Gene 1 COG0819 Putative transcription activator; putative transcriptional activator 665200 9726708 SPAP_0692 Streptococcus pneumoniae AP200 putative transcriptional activator YP_003876287.1 664532 D 574093 CDS YP_003876288.1 307067322 9726709 665562..666308 1 NC_014494.1 Operon 311 Gene 1 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 666308 9726709 SPAP_0693 Streptococcus pneumoniae AP200 hydroxyethylthiazole kinase YP_003876288.1 665562 D 574093 CDS YP_003876289.1 307067323 9726710 666310..666939 1 NC_014494.1 Operon 311 Gene 2 COG0352 Thiamine monophosphate synthase; thiamine monophosphate synthase 666939 9726710 SPAP_0694 Streptococcus pneumoniae AP200 thiamine monophosphate synthase YP_003876289.1 666310 D 574093 CDS YP_003876290.1 307067324 9726711 667498..668058 1 NC_014494.1 Operon 312 Gene 1 COG4721 Predicted membrane protein; hypothetical protein 668058 9726711 SPAP_0695 Streptococcus pneumoniae AP200 hypothetical protein YP_003876290.1 667498 D 574093 CDS YP_003876291.1 307067325 9726712 668059..669444 1 NC_014494.1 Operon 312 Gene 2 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 669444 9726712 SPAP_0696 Streptococcus pneumoniae AP200 cobalt ABC transporter ATPase YP_003876291.1 668059 D 574093 CDS YP_003876292.1 307067326 9726713 669446..670096 1 NC_014494.1 Operon 312 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 670096 9726713 SPAP_0697 Streptococcus pneumoniae AP200 hypothetical protein YP_003876292.1 669446 D 574093 CDS YP_003876293.1 307067327 9726714 670107..670799 1 NC_014494.1 Operon 312 Gene 4 COG0819 Putative transcription activator; putative transcriptional activator 670799 9726714 SPAP_0698 Streptococcus pneumoniae AP200 putative transcriptional activator YP_003876293.1 670107 D 574093 CDS YP_003876294.1 307067328 9726715 670804..671328 1 NC_014494.1 Operon 312 Gene 5 COG4732 Predicted membrane protein; hypothetical protein 671328 9726715 SPAP_0699 Streptococcus pneumoniae AP200 hypothetical protein YP_003876294.1 670804 D 574093 CDS YP_003876295.1 307067329 9726716 671328..672131 1 NC_014494.1 Operon 312 Gene 6 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 672131 9726716 SPAP_0700 Streptococcus pneumoniae AP200 hydroxyethylthiazole kinase YP_003876295.1 671328 D 574093 CDS YP_003876296.1 307067330 9726717 672124..672756 1 NC_014494.1 Operon 312 Gene 7 COG0352 Thiamine monophosphate synthase; thiamine monophosphate synthase 672756 9726717 SPAP_0701 Streptococcus pneumoniae AP200 thiamine monophosphate synthase YP_003876296.1 672124 D 574093 CDS YP_003876297.1 307067331 9726718 complement(672966..673757) 1 NC_014494.1 Operon 313 Gene 1 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 673757 9726718 SPAP_0702 Streptococcus pneumoniae AP200 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase YP_003876297.1 672966 R 574093 CDS YP_003876298.1 307067332 9726719 674123..674518 1 NC_014494.1 Operon 314 Gene 1 COG3682 Predicted transcriptional regulator; putative transcriptional regulator 674518 9726719 SPAP_0703 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876298.1 674123 D 574093 CDS YP_003876299.1 307067333 9726720 674529..674900 1 NC_014494.1 Operon 314 Gene 2 COG4633 Uncharacterized protein conserved in bacteria; hypothetical protein 674900 9726720 SPAP_0704 Streptococcus pneumoniae AP200 hypothetical protein YP_003876299.1 674529 D 574093 CDS YP_003876300.1 307067334 9726721 674910..677153 1 NC_014494.1 Operon 314 Gene 3 COG2217 Cation transport ATPase; cation transport ATPase 677153 9726721 SPAP_0705 Streptococcus pneumoniae AP200 cation transport ATPase YP_003876300.1 674910 D 574093 CDS YP_003876301.1 307067335 9726722 677360..679135 1 NC_014494.1 acetolactate synthase; pyruvate dehydrogenase (cytochrome); glyoxylate carboligase; phosphonopyruvate decarboxylase; Operon 315 Gene 1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; thiamine pyrophosphate-requiring enzyme 679135 9726722 SPAP_0706 Streptococcus pneumoniae AP200 thiamine pyrophosphate-requiring enzyme YP_003876301.1 677360 D 574093 CDS YP_003876302.1 307067336 9726723 679246..679593 1 NC_014494.1 Operon 316 Gene 1 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase 679593 9726723 SPAP_0707 Streptococcus pneumoniae AP200 lactoylglutathione lyase-like lyase YP_003876302.1 679246 D 574093 CDS YP_003876303.1 307067337 9726724 complement(679805..680218) 1 NC_014494.1 Operon 317 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 680218 9726724 SPAP_0708 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876303.1 679805 R 574093 CDS YP_003876304.1 307067338 9726725 complement(680250..680516) 1 NC_014494.1 transposase-like protein, ISSpn2 680516 9726725 SPAP_0709 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876304.1 680250 R 574093 CDS YP_003876305.1 307067339 9726726 complement(680872..680967) 1 NC_014494.1 transposase-like protein, ISSpn2 680967 9726726 SPAP_0710 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876305.1 680872 R 574093 CDS YP_003876306.1 307067340 9726727 681032..681313 1 NC_014494.1 Operon 319 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 681313 9726727 SPAP_0711 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003876306.1 681032 D 574093 CDS YP_003876307.1 307067341 9726728 681445..682389 1 NC_014494.1 Operon 320 Gene 1 COG1482 Phosphomannose isomerase; phosphomannose isomerase 682389 9726728 SPAP_0712 Streptococcus pneumoniae AP200 phosphomannose isomerase YP_003876307.1 681445 D 574093 CDS YP_003876308.1 307067342 9726729 complement(682410..683888) 1 NC_014494.1 Operon 321 Gene 1 COG0733 Na+-dependent transporters of the SNF family; Na+-dependent transporters of the SNF family 683888 9726729 SPAP_0713 Streptococcus pneumoniae AP200 Na+-dependent transporters of the SNF family YP_003876308.1 682410 R 574093 CDS YP_003876309.1 307067343 9726730 684054..684725 1 NC_014494.1 Operon 322 Gene 1 COG0789 Predicted transcriptional regulators; putative transcriptional regulator 684725 9726730 SPAP_0714 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876309.1 684054 D 574093 CDS YP_003876310.1 307067344 9726731 complement(684745..685200) 1 NC_014494.1 Operon 323 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 685200 9726731 SPAP_0715 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876310.1 684745 R 574093 CDS YP_003876311.1 307067345 9726732 complement(685220..686395) 1 NC_014494.1 Operon 323 Gene 2 COG2081 Predicted flavoproteins; putative flavoprotein 686395 9726732 SPAP_0716 Streptococcus pneumoniae AP200 putative flavoprotein YP_003876311.1 685220 R 574093 CDS YP_003876312.1 307067346 9726733 complement(686454..687299) 1 NC_014494.1 Operon 323 Gene 3 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein 687299 9726733 SPAP_0717 Streptococcus pneumoniae AP200 hypothetical protein YP_003876312.1 686454 R 574093 CDS YP_003876313.1 307067347 9726734 687424..687981 1 NC_014494.1 Operon 324 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 687981 9726734 SPAP_0718 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876313.1 687424 D 574093 CDS YP_003876314.1 307067348 9726735 688000..688467 1 NC_014494.1 Operon 324 Gene 2 COG2131 Deoxycytidylate deaminase; deoxycytidylate deaminase 688467 9726735 SPAP_0719 Streptococcus pneumoniae AP200 deoxycytidylate deaminase YP_003876314.1 688000 D 574093 CDS YP_003876315.1 307067349 9726736 688556..689185 1 NC_014494.1 Operon 324 Gene 3 COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 689185 9726736 SPAP_0720 Streptococcus pneumoniae AP200 uracil phosphoribosyltransferase YP_003876315.1 688556 D 574093 CDS YP_003876316.1 307067350 9726737 689359..689949 1 NC_014494.1 Operon 325 Gene 1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATp-dependent Clp protease 689949 9726737 SPAP_0721 Streptococcus pneumoniae AP200 ATp-dependent Clp protease YP_003876316.1 689359 D 574093 CDS YP_003876317.1 307067351 9726738 690028..690276 1 NC_014494.1 Operon 325 Gene 2 COG4471 Uncharacterized protein conserved in bacteria; hypothetical protein 690276 9726738 SPAP_0722 Streptococcus pneumoniae AP200 hypothetical protein YP_003876317.1 690028 D 574093 CDS YP_003876318.1 307067352 9726739 690377..691537 1 NC_014494.1 Operon 326 Gene 1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid ABC transporter periplasmic protein 691537 9726739 SPAP_0723 Streptococcus pneumoniae AP200 branched-chain amino acid ABC transporter periplasmic protein YP_003876318.1 690377 D 574093 CDS YP_003876319.1 307067353 9726740 691805..692674 1 NC_014494.1 Operon 326 Gene 2 COG0559 Branched-chain amino acid ABC-type transport system, permease components; branched-chain amino acid ABC transporter permease 692674 9726740 SPAP_0724 Streptococcus pneumoniae AP200 branched-chain amino acid ABC transporter permease YP_003876319.1 691805 D 574093 CDS YP_003876320.1 307067354 9726741 692678..693634 1 NC_014494.1 Operon 326 Gene 3 COG4177 ABC-type branched-chain amino acid transport system, permease component; branched-chain amino acid ABC transporter permease 693634 9726741 SPAP_0725 Streptococcus pneumoniae AP200 branched-chain amino acid ABC transporter permease YP_003876320.1 692678 D 574093 CDS YP_003876321.1 307067355 9726742 693634..694398 1 NC_014494.1 Operon 326 Gene 4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 694398 9726742 SPAP_0726 Streptococcus pneumoniae AP200 branched-chain amino acid ABC transporter ATPase YP_003876321.1 693634 D 574093 CDS YP_003876322.1 307067356 9726743 694398..695108 1 NC_014494.1 Operon 326 Gene 5 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 695108 9726743 SPAP_0727 Streptococcus pneumoniae AP200 branched-chain amino acid ABC transporter ATPase YP_003876322.1 694398 D 574093 CDS YP_003876323.1 307067357 9726744 695416..696072 1 NC_014494.1 Operon 327 Gene 1 COG0517 FOG: CBS domain; hypothetical protein 696072 9726744 SPAP_0728 Streptococcus pneumoniae AP200 hypothetical protein YP_003876323.1 695416 D 574093 CDS YP_003876324.1 307067358 9726745 696286..697275 1 NC_014494.1 Operon 328 Gene 1 COG1186 Protein chain release factor B; protein chain release factor B 697275 9726745 SPAP_0729 Streptococcus pneumoniae AP200 protein chain release factor B YP_003876324.1 696286 D 574093 CDS YP_003876325.1 307067359 9726746 697293..697985 1 NC_014494.1 Operon 328 Gene 2 COG2884 Predicted ATPase involved in cell division; putative ATPase 697985 9726746 SPAP_0730 Streptococcus pneumoniae AP200 putative ATPase YP_003876325.1 697293 D 574093 CDS YP_003876326.1 307067360 9726747 697978..698904 1 NC_014494.1 Operon 328 Gene 3 COG2177 Cell division protein; cell division protein 698904 9726747 SPAP_0731 Streptococcus pneumoniae AP200 cell division protein YP_003876326.1 697978 D 574093 CDS YP_003876327.1 307067361 9726748 698973..699068 1 NC_014494.1 Operon 329 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 699068 9726748 SPAP_0732 Streptococcus pneumoniae AP200 hypothetical protein YP_003876327.1 698973 D 574093 CDS YP_003876328.1 307067362 9726749 699190..701370 1 NC_014494.1 Operon 330 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 701370 9726749 SPAP_0733 Streptococcus pneumoniae AP200 PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC YP_003876328.1 699190 D 574093 CDS YP_003876329.1 307067363 9726750 701422..702237 1 NC_014494.1 Operon 330 Gene 2 COG3568 Metal-dependent hydrolase; metal-dependent hydrolase 702237 9726750 SPAP_0734 Streptococcus pneumoniae AP200 metal-dependent hydrolase YP_003876329.1 701422 D 574093 CDS YP_003876330.1 307067364 9726751 702377..703720 1 NC_014494.1 Operon 331 Gene 1 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase 703720 9726751 SPAP_0735 Streptococcus pneumoniae AP200 superfamily II DNA and RNA helicase YP_003876330.1 702377 D 574093 CDS YP_003876331.1 307067365 9726752 703935..705125 1 NC_014494.1 Operon 332 Gene 1 COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 705125 9726752 SPAP_0736 Streptococcus pneumoniae AP200 S-adenosylmethionine synthetase YP_003876331.1 703935 D 574093 CDS YP_003876332.1 307067366 9726753 705678..706613 1 NC_014494.1 Operon 333 Gene 1 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 706613 9726753 SPAP_0737 Streptococcus pneumoniae AP200 dihydroorotate dehydrogenase YP_003876332.1 705678 D 574093 CDS YP_003876333.1 307067367 9726754 706647..707684 1 NC_014494.1 Operon 333 Gene 2 COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 707684 9726754 SPAP_0738 Streptococcus pneumoniae AP200 DNA polymerase III subunit delta YP_003876333.1 706647 D 574093 CDS YP_003876334.1 307067368 9726755 707857..708462 1 NC_014494.1 Operon 334 Gene 1 protein supported gi|15900660|ref|NP_345264.1| superoxide dismutase, manganese-dependent; hypothetical protein 708462 9726755 SPAP_0739 Streptococcus pneumoniae AP200 hypothetical protein YP_003876334.1 707857 D 574093 CDS YP_003876335.1 307067369 9726756 708619..709149 1 NC_014494.1 Operon 335 Gene 1 COG4470 Uncharacterized protein conserved in bacteria; hypothetical protein 709149 9726756 SPAP_0740 Streptococcus pneumoniae AP200 hypothetical protein YP_003876335.1 708619 D 574093 CDS YP_003876336.1 307067370 9726757 709170..710255 1 NC_014494.1 Operon 335 Gene 2 COG0820 Predicted Fe-S-cluster redox enzyme; putative Fe-S-cluster redox enzyme 710255 9726757 SPAP_0741 Streptococcus pneumoniae AP200 putative Fe-S-cluster redox enzyme YP_003876336.1 709170 D 574093 CDS YP_003876337.1 307067371 9726758 710255..710737 1 NC_014494.1 Operon 335 Gene 3 COG4767 Glycopeptide antibiotics resistance protein; glycopeptide antibiotics resistance protein 710737 9726758 SPAP_0742 Streptococcus pneumoniae AP200 glycopeptide antibiotics resistance protein YP_003876337.1 710255 D 574093 CDS YP_003876338.1 307067372 9726759 710739..712280 1 NC_014494.1 Operon 335 Gene 4 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 712280 9726759 SPAP_0743 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876338.1 710739 D 574093 CDS YP_003876339.1 307067373 9726760 712446..713474 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 713474 9726760 SPAP_0744 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876339.1 712446 D 574093 CDS YP_003876340.1 307067374 9726761 713344..713790 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 713790 9726761 SPAP_0745 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876340.1 713344 D 574093 CDS YP_003876341.1 307067375 9726762 complement(714042..714845) 1 NC_014494.1 Operon 337 Gene 1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family 714845 9726762 SPAP_0746 Streptococcus pneumoniae AP200 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family YP_003876341.1 714042 R 574093 CDS YP_003876342.1 307067376 9726763 complement(714959..715150) 1 NC_014494.1 Operon 338 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 715150 9726763 SPAP_0747 Streptococcus pneumoniae AP200 hypothetical protein YP_003876342.1 714959 R 574093 CDS YP_003876343.1 307067377 9726764 complement(715629..715838) 1 NC_014494.1 Operon 339 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 715838 9726764 SPAP_0748 Streptococcus pneumoniae AP200 hypothetical protein YP_003876343.1 715629 R 574093 CDS YP_003876344.1 307067378 9726765 716008..716280 1 NC_014494.1 Operon 340 Gene 1 protein supported gi|148997148|ref|ZP_01824802.1| ribosomal protein S16; hypothetical protein 716280 9726765 SPAP_0749 Streptococcus pneumoniae AP200 hypothetical protein YP_003876344.1 716008 D 574093 CDS YP_003876345.1 307067379 9726766 716300..716539 1 NC_014494.1 Operon 340 Gene 2 COG1837 Predicted RNA-binding protein (contains KH domain); putative RNA-binding protein 716539 9726766 SPAP_0750 Streptococcus pneumoniae AP200 putative RNA-binding protein YP_003876345.1 716300 D 574093 CDS YP_003876346.1 307067380 9726767 717116..717904 1 NC_014494.1 Operon 341 Gene 1 protein supported gi|149007659|ref|ZP_01831276.1| 30S ribosomal protein S16; hypothetical protein 717904 9726767 SPAP_0751 Streptococcus pneumoniae AP200 hypothetical protein YP_003876346.1 717116 D 574093 CDS YP_003876347.1 307067381 9726768 717935..718060 1 NC_014494.1 Operon 341 Gene 2 COG0806 RimM protein, required for 16S rRNA processing; RimM protein, required for 16S rRNA processing 718060 9726768 SPAP_0752 Streptococcus pneumoniae AP200 RimM protein, required for 16S rRNA processing YP_003876347.1 717935 D 574093 CDS YP_003876348.1 307067382 9726769 718053..718454 1 NC_014494.1 Operon 341 Gene 3 COG0806 RimM protein, required for 16S rRNA processing; RimM protein, required for 16S rRNA processing 718454 9726769 SPAP_0753 Streptococcus pneumoniae AP200 RimM protein, required for 16S rRNA processing YP_003876348.1 718053 D 574093 CDS YP_003876349.1 307067383 9726770 718444..719163 1 NC_014494.1 Operon 341 Gene 4 COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA-(guanine-N1)-methyltransferase 719163 9726770 SPAP_0754 Streptococcus pneumoniae AP200 tRNA-(guanine-N1)-methyltransferase YP_003876349.1 718444 D 574093 CDS YP_003876350.1 307067384 9726771 719175..719513 1 NC_014494.1 Operon 341 Gene 5 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; oxygen-sensitive ribonucleoside-triphosphate reductase 719513 9726771 SPAP_0755 Streptococcus pneumoniae AP200 oxygen-sensitive ribonucleoside-triphosphate reductase YP_003876350.1 719175 D 574093 CDS YP_003876351.1 307067385 9726772 complement(719543..719863) 1 NC_014494.1 Operon 342 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 719863 9726772 SPAP_0756 Streptococcus pneumoniae AP200 hypothetical protein YP_003876351.1 719543 R 574093 CDS YP_003876352.1 307067386 9726773 719961..720176 1 NC_014494.1 Operon 343 Gene 1 COG4443 Uncharacterized protein conserved in bacteria; hypothetical protein 720176 9726773 SPAP_0757 Streptococcus pneumoniae AP200 hypothetical protein YP_003876352.1 719961 D 574093 CDS YP_003876353.1 307067387 9726774 complement(720380..720916) 1 NC_014494.1 Operon 344 Gene 1 COG1268 Uncharacterized conserved protein; hypothetical protein 720916 9726774 SPAP_0758 Streptococcus pneumoniae AP200 hypothetical protein YP_003876353.1 720380 R 574093 CDS YP_003876354.1 307067388 9726775 complement(721112..722458) 1 NC_014494.1 Operon 345 Gene 1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein 722458 9726775 SPAP_0759 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein YP_003876354.1 721112 R 574093 CDS YP_003876355.1 307067389 9726776 722744..723943 1 NC_014494.1 Operon 346 Gene 1 COG0845 Membrane-fusion protein; membrane-fusion protein 723943 9726776 SPAP_0760 Streptococcus pneumoniae AP200 membrane-fusion protein YP_003876355.1 722744 D 574093 CDS YP_003876356.1 307067390 9726777 723927..724628 1 NC_014494.1 Operon 346 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 724628 9726777 SPAP_0761 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876356.1 723927 D 574093 CDS YP_003876357.1 307067391 9726778 724630..725889 1 NC_014494.1 Operon 346 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 725889 9726778 SPAP_0762 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003876357.1 724630 D 574093 CDS YP_003876358.1 307067392 9726779 726013..728010 1 NC_014494.1 Operon 347 Gene 1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase 728010 9726779 SPAP_0763 Streptococcus pneumoniae AP200 methionyl-tRNA synthetase YP_003876358.1 726013 D 574093 CDS YP_003876359.1 307067393 9726780 728060..728341 1 NC_014494.1 Operon 347 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 728341 9726780 SPAP_0764 Streptococcus pneumoniae AP200 hypothetical protein YP_003876359.1 728060 D 574093 CDS YP_003876360.1 307067394 9726781 728431..728751 1 NC_014494.1 Operon 347 Gene 3 COG1695 Predicted transcriptional regulators; putative transcriptional regulator 728751 9726781 SPAP_0765 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876360.1 728431 D 574093 CDS YP_003876361.1 307067395 9726782 728755..729570 1 NC_014494.1 Operon 347 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 729570 9726782 SPAP_0766 Streptococcus pneumoniae AP200 hypothetical protein YP_003876361.1 728755 D 574093 CDS YP_003876362.1 307067396 9726783 729645..730571 1 NC_014494.1 Operon 347 Gene 5 COG4989 Predicted oxidoreductase; putative oxidoreductase 730571 9726783 SPAP_0767 Streptococcus pneumoniae AP200 putative oxidoreductase YP_003876362.1 729645 D 574093 CDS YP_003876363.1 307067397 9726784 730671..730907 1 NC_014494.1 Operon 348 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 730907 9726784 SPAP_0768 Streptococcus pneumoniae AP200 hypothetical protein YP_003876363.1 730671 D 574093 CDS YP_003876364.1 307067398 9726785 730900..731598 1 NC_014494.1 Operon 348 Gene 2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); fehydrogenase 731598 9726785 SPAP_0769 Streptococcus pneumoniae AP200 fehydrogenase YP_003876364.1 730900 D 574093 CDS YP_003876365.1 307067399 9726786 731609..732109 1 NC_014494.1 Operon 348 Gene 3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 732109 9726786 SPAP_0770 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876365.1 731609 D 574093 CDS YP_003876366.1 307067400 9726787 732087..732956 1 NC_014494.1 Operon 348 Gene 4 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; phosphoenolpyruvate synthase 732956 9726787 SPAP_0771 Streptococcus pneumoniae AP200 phosphoenolpyruvate synthase YP_003876366.1 732087 D 574093 CDS YP_003876367.1 307067401 9726788 732931..733371 1 NC_014494.1 Operon 348 Gene 5 COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein 733371 9726788 SPAP_0772 Streptococcus pneumoniae AP200 hypothetical protein YP_003876367.1 732931 D 574093 CDS YP_003876368.1 307067402 9726789 733494..736040 1 NC_014494.1 Operon 349 Gene 1 COG0308 Aminopeptidase N; aminopeptidase N 736040 9726789 SPAP_0773 Streptococcus pneumoniae AP200 aminopeptidase N YP_003876368.1 733494 D 574093 CDS YP_003876369.1 307067403 9726790 736148..736822 1 NC_014494.1 Operon 350 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 736822 9726790 SPAP_0774 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003876369.1 736148 D 574093 CDS YP_003876370.1 307067404 9726791 736812..738146 1 NC_014494.1 Operon 350 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 738146 9726791 SPAP_0775 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003876370.1 736812 D 574093 CDS YP_003876371.1 307067405 9726792 complement(738180..738467) 1 NC_014494.1 Operon 351 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 738467 9726792 SPAP_0776 Streptococcus pneumoniae AP200 hypothetical protein YP_003876371.1 738180 R 574093 CDS YP_003876372.1 307067406 9726793 738607..739536 1 NC_014494.1 Operon 352 Gene 1 COG0826 Collagenase and related proteases; collagenase-like protease 739536 9726793 SPAP_0777 Streptococcus pneumoniae AP200 collagenase-like protease YP_003876372.1 738607 D 574093 CDS YP_003876373.1 307067407 9726794 739736..742186 1 NC_014494.1 Operon 353 Gene 1 COG1199 Rad3-related DNA helicases; Rad3-related DNA helicase 742186 9726794 SPAP_0778 Streptococcus pneumoniae AP200 Rad3-related DNA helicase YP_003876373.1 739736 D 574093 CDS YP_003876374.1 307067408 9726795 742223..743446 1 NC_014494.1 Operon 353 Gene 2 COG0772 Bacterial cell division membrane protein; cell division membrane protein 743446 9726795 SPAP_0779 Streptococcus pneumoniae AP200 cell division membrane protein YP_003876374.1 742223 D 574093 CDS YP_003876375.1 307067409 9726796 743457..744011 1 NC_014494.1 Operon 353 Gene 3 COG0693 Putative intracellular protease/amidase; putative intracellular protease/amidase 744011 9726796 SPAP_0780 Streptococcus pneumoniae AP200 putative intracellular protease/amidase YP_003876375.1 743457 D 574093 CDS YP_003876376.1 307067410 9726797 744087..744659 1 NC_014494.1 Operon 353 Gene 4 COG0546 Predicted phosphatases; putative phosphatase 744659 9726797 SPAP_0781 Streptococcus pneumoniae AP200 putative phosphatase YP_003876376.1 744087 D 574093 CDS YP_003876377.1 307067411 9726798 744674..746620 1 NC_014494.1 Operon 353 Gene 5 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; type IIA topoisomerase subunit B 746620 9726798 SPAP_0782 Streptococcus pneumoniae AP200 type IIA topoisomerase subunit B YP_003876377.1 744674 D 574093 CDS YP_003876378.1 307067412 9726799 746702..748429 1 NC_014494.1 Operon 353 Gene 6 COG4477 Negative regulator of septation ring formation; Negative regulator of septation ring formation 748429 9726799 SPAP_0783 Streptococcus pneumoniae AP200 Negative regulator of septation ring formation YP_003876378.1 746702 D 574093 CDS YP_003876379.1 307067413 9726800 complement(749159..749482) 1 NC_014494.1 transposase-like protein, ISSpn_AP200_7 749482 9726800 SPAP_0784 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_7 YP_003876379.1 749159 R 574093 CDS YP_003876380.1 307067414 9726801 complement(749743..750042) 1 NC_014494.1 Operon 355 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 750042 9726801 SPAP_0785 Streptococcus pneumoniae AP200 hypothetical protein YP_003876380.1 749743 R 574093 CDS YP_003876381.1 307067415 9726802 complement(750207..750470) 1 NC_014494.1 Operon 356 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 750470 9726802 SPAP_0786 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876381.1 750207 R 574093 CDS YP_003876382.1 307067416 9726803 750722..751090 1 NC_014494.1 transposase-like protein, IS630 751090 9726803 SPAP_0787 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003876382.1 750722 D 574093 CDS YP_003876383.1 307067417 9726804 complement(751109..751369) 1 NC_014494.1 Operon 358 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 751369 9726804 SPAP_0788 Streptococcus pneumoniae AP200 hypothetical protein YP_003876383.1 751109 R 574093 CDS YP_003876384.1 307067418 9726805 751510..751692 1 NC_014494.1 Operon 359 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 751692 9726805 SPAP_0789 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003876384.1 751510 D 574093 CDS YP_003876385.1 307067419 9726806 complement(751899..754157) 1 NC_014494.1 Operon 360 Gene 1 protein supported gi|163764771|ref|ZP_02171825.1| ribosomal protein S8; hypothetical protein 754157 9726806 SPAP_0790 Streptococcus pneumoniae AP200 hypothetical protein YP_003876385.1 751899 R 574093 CDS YP_003876386.1 307067420 9726807 complement(754386..754616) 1 NC_014494.1 Operon 361 Gene 1 COG4703 Uncharacterized protein conserved in bacteria; hypothetical protein 754616 9726807 SPAP_0791 Streptococcus pneumoniae AP200 hypothetical protein YP_003876386.1 754386 R 574093 CDS YP_003876387.1 307067421 9726808 754806..755489 1 NC_014494.1 Operon 362 Gene 1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 755489 9726808 SPAP_0792 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003876387.1 754806 D 574093 CDS YP_003876388.1 307067422 9726809 755489..756223 1 NC_014494.1 Operon 362 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 756223 9726809 SPAP_0793 Streptococcus pneumoniae AP200 hypothetical protein YP_003876388.1 755489 D 574093 CDS YP_003876389.1 307067423 9726810 756377..757234 1 NC_014494.1 Operon 363 Gene 1 COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 757234 9726810 SPAP_0794 Streptococcus pneumoniae AP200 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase YP_003876389.1 756377 D 574093 CDS YP_003876390.1 307067424 9726811 757376..758248 1 NC_014494.1 Operon 364 Gene 1 COG0063 Predicted sugar kinase; putative sugar kinase 758248 9726811 SPAP_0795 Streptococcus pneumoniae AP200 putative sugar kinase YP_003876390.1 757376 D 574093 CDS YP_003876391.1 307067425 9726812 758530..759213 1 NC_014494.1 Operon 365 Gene 1 COG0120 Ribose 5-phosphate isomerase; ribose 5-phosphate isomerase 759213 9726812 SPAP_0796 Streptococcus pneumoniae AP200 ribose 5-phosphate isomerase YP_003876391.1 758530 D 574093 CDS YP_003876392.1 307067426 9726813 759227..760438 1 NC_014494.1 Operon 365 Gene 2 COG1015 Phosphopentomutase; phosphopentomutase 760438 9726813 SPAP_0797 Streptococcus pneumoniae AP200 phosphopentomutase YP_003876392.1 759227 D 574093 CDS YP_003876393.1 307067427 9726814 760440..760982 1 NC_014494.1 Operon 365 Gene 3 COG3797 Uncharacterized protein conserved in bacteria; hypothetical protein 760982 9726814 SPAP_0798 Streptococcus pneumoniae AP200 hypothetical protein YP_003876393.1 760440 D 574093 CDS YP_003876394.1 307067428 9726815 760998..761807 1 NC_014494.1 Operon 365 Gene 4 COG0005 Purine nucleoside phosphorylase; purine nucleoside phosphorylase 761807 9726815 SPAP_0799 Streptococcus pneumoniae AP200 purine nucleoside phosphorylase YP_003876394.1 760998 D 574093 CDS YP_003876395.1 307067429 9726816 762283..762678 1 NC_014494.1 Operon 366 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 762678 9726816 SPAP_0800 Streptococcus pneumoniae AP200 hypothetical protein YP_003876395.1 762283 D 574093 CDS YP_003876396.1 307067430 9726817 762733..763263 1 NC_014494.1 Operon 366 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 763263 9726817 SPAP_0801 Streptococcus pneumoniae AP200 hypothetical protein YP_003876396.1 762733 D 574093 CDS YP_003876397.1 307067431 9726818 763288..763800 1 NC_014494.1 Operon 366 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 763800 9726818 SPAP_0802 Streptococcus pneumoniae AP200 hypothetical protein YP_003876397.1 763288 D 574093 CDS YP_003876398.1 307067432 9726819 764454..765164 1 NC_014494.1 Operon 367 Gene 1 COG0813 Purine-nucleoside phosphorylase; purine-nucleoside phosphorylase 765164 9726819 SPAP_0803 Streptococcus pneumoniae AP200 purine-nucleoside phosphorylase YP_003876398.1 764454 D 574093 CDS YP_003876399.1 307067433 9726820 complement(765187..765711) 1 NC_014494.1 Operon 368 Gene 1 COG0563 Adenylate kinase and related kinases; adenylate kinase-like kinase 765711 9726820 SPAP_0804 Streptococcus pneumoniae AP200 adenylate kinase-like kinase YP_003876399.1 765187 R 574093 CDS YP_003876400.1 307067434 9726821 complement(765764..766015) 1 NC_014494.1 Operon 369 Gene 1 protein supported gi|242245117|ref|ZP_04799554.1| 30S ribosomal protein S20; hypothetical protein 766015 9726821 SPAP_0805 Streptococcus pneumoniae AP200 hypothetical protein YP_003876400.1 765764 R 574093 CDS YP_003876401.1 307067435 9726822 complement(766068..766988) 1 NC_014494.1 Operon 369 Gene 2 COG1072 Panthothenate kinase; panthothenate kinase 766988 9726822 SPAP_0806 Streptococcus pneumoniae AP200 panthothenate kinase YP_003876401.1 766068 R 574093 CDS YP_003876402.1 307067436 9726823 767178..767414 1 NC_014494.1 Operon 370 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 767414 9726823 SPAP_0807 Streptococcus pneumoniae AP200 hypothetical protein YP_003876402.1 767178 D 574093 CDS YP_003876403.1 307067437 9726824 767788..768378 1 NC_014494.1 Operon 371 Gene 1 COG2813 16S RNA G1207 methylase RsmC; 16S RNA G1207 methylase RsmC 768378 9726824 SPAP_0808 Streptococcus pneumoniae AP200 16S RNA G1207 methylase RsmC YP_003876403.1 767788 D 574093 CDS YP_003876404.1 307067438 9726825 768375..769652 1 NC_014494.1 Operon 371 Gene 2 COG0213 Thymidine phosphorylase; thymidine phosphorylase 769652 9726825 SPAP_0809 Streptococcus pneumoniae AP200 thymidine phosphorylase YP_003876404.1 768375 D 574093 CDS YP_003876405.1 307067439 9726826 769670..770332 1 NC_014494.1 Operon 371 Gene 3 COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 770332 9726826 SPAP_0810 Streptococcus pneumoniae AP200 deoxyribose-phosphate aldolase YP_003876405.1 769670 D 574093 CDS YP_003876406.1 307067440 9726827 770319..770708 1 NC_014494.1 Operon 371 Gene 4 COG0295 Cytidine deaminase; cytidine deaminase 770708 9726827 SPAP_0811 Streptococcus pneumoniae AP200 cytidine deaminase YP_003876406.1 770319 D 574093 CDS YP_003876407.1 307067441 9726828 770799..771851 1 NC_014494.1 Operon 371 Gene 5 COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; ABC transporter periplasmic protein/surface lipoprotein 771851 9726828 SPAP_0812 Streptococcus pneumoniae AP200 ABC transporter periplasmic protein/surface lipoprotein YP_003876407.1 770799 D 574093 CDS YP_003876408.1 307067442 9726829 771995..773530 1 NC_014494.1 Operon 371 Gene 6 COG3845 ABC-type uncharacterized transport systems, ATPase components; ABC transporter ATPase 773530 9726829 SPAP_0813 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876408.1 771995 D 574093 CDS YP_003876409.1 307067443 9726830 773523..774581 1 NC_014494.1 Operon 371 Gene 7 COG4603 ABC-type uncharacterized transport system, permease component; ABC transporter permease 774581 9726830 SPAP_0814 Streptococcus pneumoniae AP200 ABC transporter permease YP_003876409.1 773523 D 574093 CDS YP_003876410.1 307067444 9726831 774584..775540 1 NC_014494.1 Operon 371 Gene 8 COG1079 Uncharacterized ABC-type transport system, permease component; ABC transporter permease 775540 9726831 SPAP_0815 Streptococcus pneumoniae AP200 ABC transporter permease YP_003876410.1 774584 D 574093 CDS YP_003876411.1 307067445 9726832 775625..775837 1 NC_014494.1 Operon 371 Gene 9 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 775837 9726832 SPAP_0816 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876411.1 775625 D 574093 CDS YP_003876412.1 307067446 9726833 775974..776141 1 NC_014494.1 Operon 372 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 776141 9726833 SPAP_0817 Streptococcus pneumoniae AP200 hypothetical protein YP_003876412.1 775974 D 574093 CDS YP_003876413.1 307067447 9726834 776141..776974 1 NC_014494.1 Operon 372 Gene 2 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 776974 9726834 SPAP_0818 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876413.1 776141 D 574093 CDS YP_003876414.1 307067448 9726835 complement(777017..777658) 1 NC_014494.1 Operon 373 Gene 1 COG0344 Predicted membrane protein; hypothetical protein 777658 9726835 SPAP_0819 Streptococcus pneumoniae AP200 hypothetical protein YP_003876414.1 777017 R 574093 CDS YP_003876415.1 307067449 9726836 777794..779737 1 NC_014494.1 Operon 374 Gene 1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; type IIA topoisomerase subunit B 779737 9726836 SPAP_0820 Streptococcus pneumoniae AP200 type IIA topoisomerase subunit B YP_003876415.1 777794 D 574093 CDS YP_003876416.1 307067450 9726837 779752..779844 1 NC_014494.1 Operon 374 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 779844 9726837 SPAP_0821 Streptococcus pneumoniae AP200 hypothetical protein YP_003876416.1 779752 D 574093 CDS YP_003876417.1 307067451 9726838 779858..779983 1 NC_014494.1 Operon 374 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 779983 9726838 SPAP_0822 Streptococcus pneumoniae AP200 hypothetical protein YP_003876417.1 779858 D 574093 CDS YP_003876418.1 307067452 9726839 780193..782628 1 NC_014494.1 Operon 375 Gene 1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; type IIA topoisomerase subunit A 782628 9726839 SPAP_0823 Streptococcus pneumoniae AP200 type IIA topoisomerase subunit A YP_003876418.1 780193 D 574093 CDS YP_003876419.1 307067453 9726840 782760..783782 1 NC_014494.1 Operon 376 Gene 1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase 783782 9726840 SPAP_0824 Streptococcus pneumoniae AP200 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase YP_003876419.1 782760 D 574093 CDS YP_003876420.1 307067454 9726841 783838..784542 1 NC_014494.1 Operon 376 Gene 2 protein supported gi|148997067|ref|ZP_01824721.1| 30S ribosomal protein S1; hypothetical protein 784542 9726841 SPAP_0825 Streptococcus pneumoniae AP200 hypothetical protein YP_003876420.1 783838 D 574093 CDS YP_003876421.1 307067455 9726842 784607..785296 1 NC_014494.1 Operon 376 Gene 3 COG3819 Predicted membrane protein; hypothetical protein 785296 9726842 SPAP_0826 Streptococcus pneumoniae AP200 hypothetical protein YP_003876421.1 784607 D 574093 CDS YP_003876422.1 307067456 9726843 785293..786216 1 NC_014494.1 Operon 376 Gene 4 COG3817 Predicted membrane protein; hypothetical protein 786216 9726843 SPAP_0827 Streptococcus pneumoniae AP200 hypothetical protein YP_003876422.1 785293 D 574093 CDS YP_003876423.1 307067457 9726844 786231..786875 1 NC_014494.1 Operon 376 Gene 5 COG2039; N-terminal pyroglutamyl peptidase; pyrrolidone-carboxylate peptidase 786875 9726844 SPAP_0828 Streptococcus pneumoniae AP200 pyrrolidone-carboxylate peptidase YP_003876423.1 786231 D 574093 CDS YP_003876424.1 307067458 9726845 787043..787273 1 NC_014494.1 Operon 376 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 787273 9726845 SPAP_0829 Streptococcus pneumoniae AP200 hypothetical protein YP_003876424.1 787043 D 574093 CDS YP_003876425.1 307067459 9726848 787646..788848 1 NC_014494.1 Operon 377 Gene 1 protein supported gi|15902808|ref|NP_358358.1| 30S ribosomal protein S1; hypothetical protein 788848 9726848 SPAP_0832 Streptococcus pneumoniae AP200 hypothetical protein YP_003876425.1 787646 D 574093 CDS YP_003876426.1 307067460 9726849 complement(788933..789472) 1 NC_014494.1 Operon 378 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 789472 9726849 SPAP_0833 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876426.1 788933 R 574093 CDS YP_003876427.1 307067461 9726850 complement(789732..790250) 1 NC_014494.1 Operon 379 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 790250 9726850 SPAP_0834 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876427.1 789732 R 574093 CDS YP_003876428.1 307067462 9726851 790444..790941 1 NC_014494.1 Operon 380 Gene 1 protein supported gi|15900747|ref|NP_345351.1| hypothetical protein SP_0864; hypothetical protein 790941 9726851 SPAP_0835 Streptococcus pneumoniae AP200 hypothetical protein YP_003876428.1 790444 D 574093 CDS YP_003876429.1 307067463 9726852 790941..792596 1 NC_014494.1 Operon 380 Gene 2 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma/tau 792596 9726852 SPAP_0836 Streptococcus pneumoniae AP200 DNA polymerase III subunits gamma/tau YP_003876429.1 790941 D 574093 CDS YP_003876430.1 307067464 9726853 792624..792818 1 NC_014494.1 Operon 380 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 792818 9726853 SPAP_0837 Streptococcus pneumoniae AP200 hypothetical protein YP_003876430.1 792624 D 574093 CDS YP_003876431.1 307067465 9726854 792968..793738 1 NC_014494.1 Operon 381 Gene 1 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Fe-S cluster assemble ABC transporter ATPase 793738 9726854 SPAP_0838 Streptococcus pneumoniae AP200 Fe-S cluster assemble ABC transporter ATPase YP_003876431.1 792968 D 574093 CDS YP_003876432.1 307067466 9726855 793766..795028 1 NC_014494.1 Operon 381 Gene 2 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Fe-S cluster assemble ABC transporter permease 795028 9726855 SPAP_0839 Streptococcus pneumoniae AP200 Fe-S cluster assemble ABC transporter permease YP_003876432.1 793766 D 574093 CDS YP_003876433.1 307067467 9726856 795039..796265 1 NC_014494.1 Operon 381 Gene 3 COG0520 Selenocysteine lyase; selenocysteine lyase 796265 9726856 SPAP_0840 Streptococcus pneumoniae AP200 selenocysteine lyase YP_003876433.1 795039 D 574093 CDS YP_003876434.1 307067468 9726857 796252..796692 1 NC_014494.1 Operon 381 Gene 4 COG0822 NifU homolog involved in Fe-S cluster formation; NifU-like protein 796692 9726857 SPAP_0841 Streptococcus pneumoniae AP200 NifU-like protein YP_003876434.1 796252 D 574093 CDS YP_003876435.1 307067469 9726858 796746..798158 1 NC_014494.1 Operon 381 Gene 5 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Fe-S cluster assemble ABC transporter permease 798158 9726858 SPAP_0842 Streptococcus pneumoniae AP200 Fe-S cluster assemble ABC transporter permease YP_003876435.1 796746 D 574093 CDS YP_003876436.1 307067470 9726859 complement(798389..799630) 1 NC_014494.1 Operon 382 Gene 1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 799630 9726859 SPAP_0843 Streptococcus pneumoniae AP200 D-alanyl-D-alanine carboxypeptidase YP_003876436.1 798389 R 574093 CDS YP_003876437.1 307067471 9726860 799733..800842 1 NC_014494.1 Operon 383 Gene 1 COG0628 Predicted permease; putative permease 800842 9726860 SPAP_0844 Streptococcus pneumoniae AP200 putative permease YP_003876437.1 799733 D 574093 CDS YP_003876438.1 307067472 9726861 801772..801987 1 NC_014494.1 Operon 384 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 801987 9726861 SPAP_0845 Streptococcus pneumoniae AP200 hypothetical protein YP_003876438.1 801772 D 574093 CDS YP_003876439.1 307067473 9726863 802254..802994 1 NC_014494.1 Operon 384 Gene 3 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 802994 9726863 SPAP_0848 Streptococcus pneumoniae AP200 sugar metabolism transcriptional regulator YP_003876439.1 802254 D 574093 CDS YP_003876440.1 307067474 9726864 802991..803902 1 NC_014494.1 Operon 384 Gene 4 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB 803902 9726864 SPAP_0849 Streptococcus pneumoniae AP200 fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB YP_003876440.1 802991 D 574093 CDS YP_003876441.1 307067475 9726865 803899..805851 1 NC_014494.1 Operon 384 Gene 5 COG1299 Phosphotransferase system, fructose-specific IIC component; PTS system fructose-specific transporter subunit IIC 805851 9726865 SPAP_0850 Streptococcus pneumoniae AP200 PTS system fructose-specific transporter subunit IIC YP_003876441.1 803899 D 574093 CDS YP_003876442.1 307067476 9726866 805937..808240 1 NC_014494.1 Operon 384 Gene 6 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA segregation ATPase FtsK/SpoIIIE-like protein 808240 9726866 SPAP_0851 Streptococcus pneumoniae AP200 DNA segregation ATPase FtsK/SpoIIIE-like protein YP_003876442.1 805937 D 574093 CDS YP_003876443.1 307067477 9726867 complement(808284..808718) 1 NC_014494.1 Operon 385 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 808718 9726867 SPAP_0852 Streptococcus pneumoniae AP200 hypothetical protein YP_003876443.1 808284 R 574093 CDS YP_003876444.1 307067478 9726868 808881..809621 1 NC_014494.1 Operon 386 Gene 1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; transposase-like protein, IS1515 809621 9726868 SPAP_0853 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876444.1 808881 D 574093 CDS YP_003876445.1 307067479 9726869 809633..810010 1 NC_014494.1 Operon 386 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 810010 9726869 SPAP_0854 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876445.1 809633 D 574093 CDS YP_003876446.1 307067480 9726870 810036..811838 1 NC_014494.1 Operon 386 Gene 3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 811838 9726870 SPAP_0855 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876446.1 810036 D 574093 CDS YP_003876447.1 307067481 9726871 811848..812225 1 NC_014494.1 Operon 386 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 812225 9726871 SPAP_0856 Streptococcus pneumoniae AP200 hypothetical protein YP_003876447.1 811848 D 574093 CDS YP_003876448.1 307067482 9726872 812385..813527 1 NC_014494.1 Operon 387 Gene 1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine sulfinate desulfinase/cysteine desulfurase-like protein 813527 9726872 SPAP_0857 Streptococcus pneumoniae AP200 cysteine sulfinate desulfinase/cysteine desulfurase-like protein YP_003876448.1 812385 D 574093 CDS YP_003876449.1 307067483 9726873 813536..814750 1 NC_014494.1 Operon 387 Gene 2 COG0301 Thiamine biosynthesis ATP pyrophosphatase; thiamine biosynthesis ATP pyrophosphatase 814750 9726873 SPAP_0858 Streptococcus pneumoniae AP200 thiamine biosynthesis ATP pyrophosphatase YP_003876449.1 813536 D 574093 CDS YP_003876450.1 307067484 9726874 814885..815457 1 NC_014494.1 Operon 388 Gene 1 COG2819 Predicted hydrolase of the alpha/beta superfamily; putative alpha/beta superfamily hydrolase 815457 9726874 SPAP_0859 Streptococcus pneumoniae AP200 putative alpha/beta superfamily hydrolase YP_003876450.1 814885 D 574093 CDS YP_003876451.1 307067485 9726875 815720..816055 1 NC_014494.1 Operon 389 Gene 1 COG4947 Uncharacterized protein conserved in bacteria; hypothetical protein 816055 9726875 SPAP_0860 Streptococcus pneumoniae AP200 hypothetical protein YP_003876451.1 815720 D 574093 CDS YP_003876452.1 307067486 9726876 816052..816459 1 NC_014494.1 Operon 389 Gene 2 COG4947 Uncharacterized protein conserved in bacteria; hypothetical protein 816459 9726876 SPAP_0861 Streptococcus pneumoniae AP200 hypothetical protein YP_003876452.1 816052 D 574093 CDS YP_003876453.1 307067487 9726877 816472..817638 1 NC_014494.1 Operon 389 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 817638 9726877 SPAP_0862 Streptococcus pneumoniae AP200 hypothetical protein YP_003876453.1 816472 D 574093 CDS YP_003876454.1 307067488 9726878 818146..818859 1 NC_014494.1 Operon 390 Gene 1 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit 818859 9726878 SPAP_0863 Streptococcus pneumoniae AP200 type I restriction-modification system methyltransferase subunit YP_003876454.1 818146 D 574093 CDS YP_003876455.1 307067489 9726879 818937..819182 1 NC_014494.1 Operon 390 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 819182 9726879 SPAP_0864 Streptococcus pneumoniae AP200 hypothetical protein YP_003876455.1 818937 D 574093 CDS YP_003876456.1 307067490 9726880 819264..820037 1 NC_014494.1 Operon 391 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 820037 9726880 SPAP_0865 Streptococcus pneumoniae AP200 hypothetical protein YP_003876456.1 819264 D 574093 CDS YP_003876457.1 307067491 9726881 820034..820861 1 NC_014494.1 Operon 391 Gene 2 COG1484 DNA replication protein; DNA replication protein 820861 9726881 SPAP_0866 Streptococcus pneumoniae AP200 DNA replication protein YP_003876457.1 820034 D 574093 CDS YP_003876458.1 307067492 9726882 820854..821339 1 NC_014494.1 Operon 391 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 821339 9726882 SPAP_0867 Streptococcus pneumoniae AP200 hypothetical protein YP_003876458.1 820854 D 574093 CDS YP_003876459.1 307067493 9726883 821336..822070 1 NC_014494.1 Operon 391 Gene 4 COG3645 Uncharacterized phage-encoded protein; hypothetical protein 822070 9726883 SPAP_0868 Streptococcus pneumoniae AP200 hypothetical protein YP_003876459.1 821336 D 574093 CDS YP_003876460.1 307067494 9726884 822048..823859 1 NC_014494.1 similar to MGAS10750_Spy1683; TraG/TraD family member; type IV secretory pathway protein VirD4 823859 9726884 SPAP_0869 Streptococcus pneumoniae AP200 type IV secretory pathway protein VirD4 YP_003876460.1 822048 D 574093 CDS YP_003876461.1 307067495 9726885 823942..824412 1 NC_014494.1 Operon 391 Gene 6 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 824412 9726885 SPAP_0870 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876461.1 823942 D 574093 CDS YP_003876462.1 307067496 9726886 824681..824875 1 NC_014494.1 Operon 392 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 824875 9726886 SPAP_0871 Streptococcus pneumoniae AP200 hypothetical protein YP_003876462.1 824681 D 574093 CDS YP_003876463.1 307067497 9726887 824939..825457 1 NC_014494.1 Operon 392 Gene 2 COG4283 Uncharacterized conserved protein; hypothetical protein 825457 9726887 SPAP_0872 Streptococcus pneumoniae AP200 hypothetical protein YP_003876463.1 824939 D 574093 CDS YP_003876464.1 307067498 9726888 825495..825917 1 NC_014494.1 Operon 392 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 825917 9726888 SPAP_0873 Streptococcus pneumoniae AP200 hypothetical protein YP_003876464.1 825495 D 574093 CDS YP_003876465.1 307067499 9726889 825985..826602 1 NC_014494.1 Operon 392 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 826602 9726889 SPAP_0874 Streptococcus pneumoniae AP200 hypothetical protein YP_003876465.1 825985 D 574093 CDS YP_003876466.1 307067500 9726890 826824..827135 1 NC_014494.1 Operon 393 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 827135 9726890 SPAP_0875 Streptococcus pneumoniae AP200 hypothetical protein YP_003876466.1 826824 D 574093 CDS YP_003876467.1 307067501 9726891 827137..827352 1 NC_014494.1 Operon 393 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 827352 9726891 SPAP_0876 Streptococcus pneumoniae AP200 hypothetical protein YP_003876467.1 827137 D 574093 CDS YP_003876468.1 307067502 9726892 827363..828226 1 NC_014494.1 Operon 393 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 828226 9726892 SPAP_0877 Streptococcus pneumoniae AP200 hypothetical protein YP_003876468.1 827363 D 574093 CDS YP_003876469.1 307067503 9726893 828236..828526 1 NC_014494.1 Operon 393 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 828526 9726893 SPAP_0878 Streptococcus pneumoniae AP200 hypothetical protein YP_003876469.1 828236 D 574093 CDS YP_003876470.1 307067504 9726894 828528..828938 1 NC_014494.1 Operon 393 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 828938 9726894 SPAP_0879 Streptococcus pneumoniae AP200 hypothetical protein YP_003876470.1 828528 D 574093 CDS YP_003876471.1 307067505 9726895 828829..831252 1 NC_014494.1 Operon 393 Gene 6 COG3451 Type IV secretory pathway, VirB4 components; type IV secretory pathway, VirB4 component 831252 9726895 SPAP_0880 Streptococcus pneumoniae AP200 type IV secretory pathway, VirB4 component YP_003876471.1 828829 D 574093 CDS YP_003876472.1 307067506 9726896 831260..833839 1 NC_014494.1 Operon 393 Gene 7 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); cell wall-associated hydrolase 833839 9726896 SPAP_0881 Streptococcus pneumoniae AP200 cell wall-associated hydrolase YP_003876472.1 831260 D 574093 CDS YP_003876473.1 307067507 9726897 833854..834093 1 NC_014494.1 Operon 393 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 834093 9726897 SPAP_0882 Streptococcus pneumoniae AP200 hypothetical protein YP_003876473.1 833854 D 574093 CDS YP_003876474.1 307067508 9726898 834080..835663 1 NC_014494.1 Operon 393 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 835663 9726898 SPAP_0883 Streptococcus pneumoniae AP200 hypothetical protein YP_003876474.1 834080 D 574093 CDS YP_003876475.1 307067509 9726899 835678..836544 1 NC_014494.1 Operon 393 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 836544 9726899 SPAP_0884 Streptococcus pneumoniae AP200 hypothetical protein YP_003876475.1 835678 D 574093 CDS YP_003876476.1 307067510 9726900 836656..837231 1 NC_014494.1 Operon 394 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 837231 9726900 SPAP_0885 Streptococcus pneumoniae AP200 hypothetical protein YP_003876476.1 836656 D 574093 CDS YP_003876477.1 307067511 9726901 837224..838207 1 NC_014494.1 Operon 394 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 838207 9726901 SPAP_0886 Streptococcus pneumoniae AP200 hypothetical protein YP_003876477.1 837224 D 574093 CDS YP_003876478.1 307067512 9726902 838300..840021 1 NC_014494.1 Operon 395 Gene 1 COG0550 Topoisomerase IA; topoisomerase IA 840021 9726902 SPAP_0887 Streptococcus pneumoniae AP200 topoisomerase IA YP_003876478.1 838300 D 574093 CDS YP_003876479.1 307067513 9726903 840014..840979 1 NC_014494.1 Operon 395 Gene 2 COG0270 Site-specific DNA methylase; site-specific DNA methylase 840979 9726903 SPAP_0888 Streptococcus pneumoniae AP200 site-specific DNA methylase YP_003876479.1 840014 D 574093 CDS YP_003876480.1 307067514 9726904 840966..847262 1 NC_014494.1 Operon 395 Gene 3 COG4646 DNA methylase; DNA methylase 847262 9726904 SPAP_0889 Streptococcus pneumoniae AP200 DNA methylase YP_003876480.1 840966 D 574093 CDS YP_003876481.1 307067515 9726905 847818..849353 1 NC_014494.1 Operon 396 Gene 1 COG3344 Retron-type reverse transcriptase; retron-type reverse transcriptase 849353 9726905 SPAP_0890 Streptococcus pneumoniae AP200 retron-type reverse transcriptase YP_003876481.1 847818 D 574093 CDS YP_003876482.1 307067516 9726906 850994..851650 1 NC_014494.1 Operon 397 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 851650 9726906 SPAP_0891 Streptococcus pneumoniae AP200 hypothetical protein YP_003876482.1 850994 D 574093 CDS YP_003876483.1 307067517 9726907 852209..852835 1 NC_014494.1 Operon 398 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 852835 9726907 SPAP_0892 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876483.1 852209 D 574093 CDS YP_003876484.1 307067518 9726908 852920..853801 1 NC_014494.1 Operon 398 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 853801 9726908 SPAP_0893 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003876484.1 852920 D 574093 CDS YP_003876485.1 307067519 9726909 853734..855440 1 NC_014494.1 similar to MGAS10750_Spy170; tetronasin resistance transmembrane protein 855440 9726909 SPAP_0894 Streptococcus pneumoniae AP200 tetronasin resistance transmembrane protein YP_003876485.1 853734 D 574093 CDS YP_003876486.1 307067520 9726910 complement(856021..856227) 1 NC_014494.1 Operon 399 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 856227 9726910 SPAP_0895 Streptococcus pneumoniae AP200 hypothetical protein YP_003876486.1 856021 R 574093 CDS YP_003876487.1 307067521 9726911 856174..856905 1 NC_014494.1 Operon 400 Gene 1 COG0030 Dimethyladenosine transferase (rRNA methylation); dimethyladenosine transferase 856905 erm(TR) 9726911 erm(TR) Streptococcus pneumoniae AP200 dimethyladenosine transferase YP_003876487.1 856174 D 574093 CDS YP_003876488.1 307067522 9726912 857122..857646 1 NC_014494.1 Operon 401 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 857646 9726912 SPAP_0897 Streptococcus pneumoniae AP200 hypothetical protein YP_003876488.1 857122 D 574093 CDS YP_003876489.1 307067523 9726913 858667..859092 1 NC_014494.1 Operon 402 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 859092 9726913 SPAP_0898 Streptococcus pneumoniae AP200 hypothetical protein YP_003876489.1 858667 D 574093 CDS YP_003876490.1 307067524 9726914 859297..859650 1 NC_014494.1 Operon 403 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 859650 9726914 SPAP_0899 Streptococcus pneumoniae AP200 hypothetical protein YP_003876490.1 859297 D 574093 CDS YP_003876491.1 307067525 9726915 complement(860132..861472) 1 NC_014494.1 Operon 404 Gene 1 COG3843 Type IV secretory pathway, VirD2 components (relaxase); type IV secretory pathway, VirD2 components (relaxase) 861472 9726915 SPAP_0900 Streptococcus pneumoniae AP200 type IV secretory pathway, VirD2 components (relaxase) YP_003876491.1 860132 R 574093 CDS YP_003876492.1 307067526 9726916 complement(861465..861821) 1 NC_014494.1 Operon 404 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 861821 9726916 SPAP_0901 Streptococcus pneumoniae AP200 hypothetical protein YP_003876492.1 861465 R 574093 CDS YP_003876493.1 307067527 9726917 complement(862000..862335) 1 NC_014494.1 Operon 405 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 862335 9726917 SPAP_0902 Streptococcus pneumoniae AP200 hypothetical protein YP_003876493.1 862000 R 574093 CDS YP_003876494.1 307067528 9726918 complement(862328..862561) 1 NC_014494.1 Operon 405 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 862561 9726918 SPAP_0903 Streptococcus pneumoniae AP200 hypothetical protein YP_003876494.1 862328 R 574093 CDS YP_003876495.1 307067529 9726919 complement(862668..863150) 1 NC_014494.1 Operon 406 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 863150 9726919 SPAP_0904 Streptococcus pneumoniae AP200 hypothetical protein YP_003876495.1 862668 R 574093 CDS YP_003876496.1 307067530 9726920 complement(863159..863707) 1 NC_014494.1 Operon 406 Gene 2 COG2856 Predicted Zn peptidase; putative Zn peptidase 863707 9726920 SPAP_0905 Streptococcus pneumoniae AP200 putative Zn peptidase YP_003876496.1 863159 R 574093 CDS YP_003876497.1 307067531 9726921 complement(863716..864117) 1 NC_014494.1 Operon 406 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 864117 9726921 SPAP_0906 Streptococcus pneumoniae AP200 hypothetical protein YP_003876497.1 863716 R 574093 CDS YP_003876498.1 307067532 9726922 864267..864827 1 NC_014494.1 similar to MGAS10750_Spy1715; hypothetical protein 864827 9726922 SPAP_0907 Streptococcus pneumoniae AP200 hypothetical protein YP_003876498.1 864267 D 574093 CDS YP_003876499.1 307067533 9726923 865097..865507 1 NC_014494.1 Operon 407 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 865507 9726923 SPAP_0908 Streptococcus pneumoniae AP200 hypothetical protein YP_003876499.1 865097 D 574093 CDS YP_003876500.1 307067534 9726924 865984..866205 1 NC_014494.1 similar to HP Uuresero_01771 Ureaplasma urealyticum serovar 9; hypothetical protein 866205 9726924 SPAP_0909 Streptococcus pneumoniae AP200 hypothetical protein YP_003876500.1 865984 D 574093 CDS YP_003876501.1 307067535 9726925 866306..867976 1 NC_014494.1 Operon 409 Gene 1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase 867976 9726925 SPAP_0910 Streptococcus pneumoniae AP200 site-specific recombinase YP_003876501.1 866306 D 574093 CDS YP_003876502.1 307067536 9726926 867976..869646 1 NC_014494.1 similar to MGAS10750_Spy1718; site-specific recombinase 869646 9726926 SPAP_0911 Streptococcus pneumoniae AP200 site-specific recombinase YP_003876502.1 867976 D 574093 CDS YP_003876503.1 307067537 9726927 869639..871132 1 NC_014494.1 Operon 410 Gene 2 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase 871132 9726927 SPAP_0912 Streptococcus pneumoniae AP200 site-specific recombinase YP_003876503.1 869639 D 574093 CDS YP_003876504.1 307067538 9726928 871308..872099 1 NC_014494.1 Operon 411 Gene 1 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit 872099 9726928 SPAP_0913 Streptococcus pneumoniae AP200 type I restriction-modification system methyltransferase subunit YP_003876504.1 871308 D 574093 CDS YP_003876505.1 307067539 9726929 872112..872654 1 NC_014494.1 Operon 411 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 872654 9726929 SPAP_0914 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876505.1 872112 D 574093 CDS YP_003876506.1 307067540 9726930 872651..873238 1 NC_014494.1 Operon 411 Gene 3 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 873238 9726930 SPAP_0915 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876506.1 872651 D 574093 CDS YP_003876507.1 307067541 9726931 873298..873534 1 NC_014494.1 Operon 411 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 873534 9726931 SPAP_0916 Streptococcus pneumoniae AP200 hypothetical protein YP_003876507.1 873298 D 574093 CDS YP_003876508.1 307067542 9726932 873531..873944 1 NC_014494.1 Operon 411 Gene 5 COG3654 Prophage maintenance system killer protein; prophage maintenance system killer protein 873944 9726932 SPAP_0917 Streptococcus pneumoniae AP200 prophage maintenance system killer protein YP_003876508.1 873531 D 574093 CDS YP_003876509.1 307067543 9726933 874062..875027 1 NC_014494.1 Operon 412 Gene 1 COG0582 Integrase; integrase 875027 9726933 SPAP_0918 Streptococcus pneumoniae AP200 integrase YP_003876509.1 874062 D 574093 CDS YP_003876510.1 307067544 9726934 875050..875631 1 NC_014494.1 Operon 412 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 875631 9726934 SPAP_0919 Streptococcus pneumoniae AP200 restriction endonuclease S subunit YP_003876510.1 875050 D 574093 CDS YP_003876511.1 307067545 9726935 875661..879011 1 NC_014494.1 Operon 412 Gene 3 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I site-specific restriction-modification system protein R 879011 9726935 SPAP_0920 Streptococcus pneumoniae AP200 type I site-specific restriction-modification system protein R YP_003876511.1 875661 D 574093 CDS YP_003876512.1 307067546 9726936 879307..879552 1 NC_014494.1 Operon 413 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 879552 9726936 SPAP_0921 Streptococcus pneumoniae AP200 hypothetical protein YP_003876512.1 879307 D 574093 CDS YP_003876513.1 307067547 9726937 complement(879646..880116) 1 NC_014494.1 Operon 414 Gene 1 COG1438 Arginine repressor; arginine repressor 880116 9726937 SPAP_0922 Streptococcus pneumoniae AP200 arginine repressor YP_003876513.1 879646 R 574093 CDS YP_003876514.1 307067548 9726938 complement(880133..882406) 1 NC_014494.1 Operon 414 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 882406 9726938 SPAP_0923 Streptococcus pneumoniae AP200 hypothetical protein YP_003876514.1 880133 R 574093 CDS YP_003876515.1 307067549 9726939 882753..885854 1 NC_014494.1 Operon 415 Gene 1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 885854 9726939 SPAP_0924 Streptococcus pneumoniae AP200 DNA polymerase III subunit alpha YP_003876515.1 882753 D 574093 CDS YP_003876516.1 307067550 9726940 885937..886944 1 NC_014494.1 Operon 415 Gene 2 COG0205 6-phosphofructokinase; 6-phosphofructokinase 886944 9726940 SPAP_0925 Streptococcus pneumoniae AP200 6-phosphofructokinase YP_003876516.1 885937 D 574093 CDS YP_003876517.1 307067551 9726941 887003..888508 1 NC_014494.1 Operon 415 Gene 3 COG0469 Pyruvate kinase; pyruvate kinase 888508 9726941 SPAP_0926 Streptococcus pneumoniae AP200 pyruvate kinase YP_003876517.1 887003 D 574093 CDS YP_003876518.1 307067552 9726942 complement(888686..888928) 1 NC_014494.1 Operon 416 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 888928 9726942 SPAP_0927 Streptococcus pneumoniae AP200 hypothetical protein YP_003876518.1 888686 R 574093 CDS YP_003876519.1 307067553 9726943 complement(889582..889728) 1 NC_014494.1 Operon 417 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 889728 9726943 SPAP_0928 Streptococcus pneumoniae AP200 hypothetical protein YP_003876519.1 889582 R 574093 CDS YP_003876520.1 307067554 9726944 890272..891144 1 NC_014494.1 Operon 418 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 891144 9726944 SPAP_0929 Streptococcus pneumoniae AP200 hypothetical protein YP_003876520.1 890272 D 574093 CDS YP_003876521.1 307067555 9726945 complement(891251..891634) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 891634 9726945 SPAP_0930 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876521.1 891251 R 574093 CDS YP_003876522.1 307067556 9726946 891777..892088 1 NC_014494.1 Operon 420 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 892088 9726946 SPAP_0931 Streptococcus pneumoniae AP200 hypothetical protein YP_003876522.1 891777 D 574093 CDS YP_003876523.1 307067557 9726947 892092..892808 1 NC_014494.1 Operon 420 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 892808 9726947 SPAP_0932 Streptococcus pneumoniae AP200 hypothetical protein YP_003876523.1 892092 D 574093 CDS YP_003876524.1 307067558 9726948 complement(892937..893752) 1 NC_014494.1 Operon 421 Gene 1 COG3689 Predicted membrane protein; hypothetical protein 893752 9726948 SPAP_0933 Streptococcus pneumoniae AP200 hypothetical protein YP_003876524.1 892937 R 574093 CDS YP_003876525.1 307067559 9726949 complement(893749..894654) 1 NC_014494.1 Operon 421 Gene 2 COG0701 Predicted permeases; putative permease 894654 9726949 SPAP_0934 Streptococcus pneumoniae AP200 putative permease YP_003876525.1 893749 R 574093 CDS YP_003876526.1 307067560 9726950 complement(894655..894786) 1 NC_014494.1 Operon 421 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 894786 9726950 SPAP_0935 Streptococcus pneumoniae AP200 hypothetical protein YP_003876526.1 894655 R 574093 CDS YP_003876527.1 307067561 9726951 894674..894805 1 NC_014494.1 Operon 422 Gene 1 protein supported gi|148998378|ref|ZP_01825820.1| 50S ribosomal protein L21; hypothetical protein 894805 9726951 SPAP_0936 Streptococcus pneumoniae AP200 hypothetical protein YP_003876527.1 894674 D 574093 CDS YP_003876528.1 307067562 9726952 895066..897195 1 NC_014494.1 Operon 423 Gene 1 COG2183 Transcriptional accessory protein; transcriptional accessory protein 897195 9726952 SPAP_0937 Streptococcus pneumoniae AP200 transcriptional accessory protein YP_003876528.1 895066 D 574093 CDS YP_003876529.1 307067563 9726953 897182..897631 1 NC_014494.1 Operon 423 Gene 2 COG3091 Uncharacterized protein conserved in bacteria; hypothetical protein 897631 9726953 SPAP_0938 Streptococcus pneumoniae AP200 hypothetical protein YP_003876529.1 897182 D 574093 CDS YP_003876530.1 307067564 9726954 897690..897962 1 NC_014494.1 Operon 423 Gene 3 COG1983 Putative stress-responsive transcriptional regulator; putative stress-responsive transcriptional regulator 897962 9726954 SPAP_0939 Streptococcus pneumoniae AP200 putative stress-responsive transcriptional regulator YP_003876530.1 897690 D 574093 CDS YP_003876531.1 307067565 9726955 complement(898317..898508) 1 NC_014494.1 Operon 424 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 898508 9726955 SPAP_0940 Streptococcus pneumoniae AP200 hypothetical protein YP_003876531.1 898317 R 574093 CDS YP_003876532.1 307067566 9726956 898811..898921 1 NC_014494.1 Operon 425 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 898921 9726956 SPAP_0941 Streptococcus pneumoniae AP200 hypothetical protein YP_003876532.1 898811 D 574093 CDS YP_003876533.1 307067567 9726957 898936..899694 1 NC_014494.1 Operon 425 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 899694 9726957 SPAP_0942 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876533.1 898936 D 574093 CDS YP_003876534.1 307067568 9726958 899696..901684 1 NC_014494.1 Operon 425 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 901684 9726958 SPAP_0943 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003876534.1 899696 D 574093 CDS YP_003876535.1 307067569 9726959 complement(901726..902316) 1 NC_014494.1 Operon 426 Gene 1 COG1814 Uncharacterized membrane protein; hypothetical protein 902316 9726959 SPAP_0944 Streptococcus pneumoniae AP200 hypothetical protein YP_003876535.1 901726 R 574093 CDS YP_003876536.1 307067570 9726960 complement(902342..902869) 1 NC_014494.1 transposase-like protein, IS1239 902869 9726960 SPAP_0945 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876536.1 902342 R 574093 CDS YP_003876537.1 307067571 9726961 complement(902856..903440) 1 NC_014494.1 transposase-like protein, IS1239 903440 9726961 SPAP_0946 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876537.1 902856 R 574093 CDS YP_003876538.1 307067572 9726962 904055..905530 1 NC_014494.1 Operon 427 Gene 1 COG1982 Arginine/lysine/ornithine decarboxylases; arginine/lysine/ornithine decarboxylase 905530 9726962 SPAP_0947 Streptococcus pneumoniae AP200 arginine/lysine/ornithine decarboxylase YP_003876538.1 904055 D 574093 CDS YP_003876539.1 307067573 9726963 complement(905874..906527) 1 NC_014494.1 Operon 428 Gene 1 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 906527 9726963 SPAP_0948 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_1 YP_003876539.1 905874 R 574093 CDS YP_003876540.1 307067574 9726964 complement(906644..906766) 1 NC_014494.1 transposase-like protein, ISSpn_AP200_1 906766 9726964 SPAP_0949 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_1 YP_003876540.1 906644 R 574093 CDS YP_003876541.1 307067575 9726965 907022..907882 1 NC_014494.1 Operon 430 Gene 1 COG0421 Spermidine synthase; spermidine synthase 907882 9726965 SPAP_0950 Streptococcus pneumoniae AP200 spermidine synthase YP_003876541.1 907022 D 574093 CDS YP_003876542.1 307067576 9726966 907879..909138 1 NC_014494.1 Operon 430 Gene 2 COG1748 Saccharopine dehydrogenase and related proteins; Saccharopine dehydrogenase-like protein 909138 9726966 SPAP_0951 Streptococcus pneumoniae AP200 Saccharopine dehydrogenase-like protein YP_003876542.1 907879 D 574093 CDS YP_003876543.1 307067577 9726967 909138..910265 1 NC_014494.1 Operon 430 Gene 3 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 910265 9726967 SPAP_0952 Streptococcus pneumoniae AP200 diaminopimelate decarboxylase YP_003876543.1 909138 D 574093 CDS YP_003876544.1 307067578 9726968 910262..911347 1 NC_014494.1 Operon 430 Gene 4 COG2957 Peptidylarginine deiminase and related enzymes; peptidylarginine deiminase-like enzyme 911347 9726968 SPAP_0953 Streptococcus pneumoniae AP200 peptidylarginine deiminase-like enzyme YP_003876544.1 910262 D 574093 CDS YP_003876545.1 307067579 9726969 911357..912232 1 NC_014494.1 Operon 430 Gene 5 COG0388 Predicted amidohydrolase; putative amidohydrolase 912232 9726969 SPAP_0954 Streptococcus pneumoniae AP200 putative amidohydrolase YP_003876545.1 911357 D 574093 CDS YP_003876546.1 307067580 9726970 complement(912413..913222) 1 NC_014494.1 Operon 431 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 913222 9726970 SPAP_0955 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003876546.1 912413 R 574093 CDS YP_003876547.1 307067581 9726971 913494..913715 1 NC_014494.1 Operon 432 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 913715 9726971 SPAP_0956 Streptococcus pneumoniae AP200 hypothetical protein YP_003876547.1 913494 D 574093 CDS YP_003876548.1 307067582 9726972 913769..914440 1 NC_014494.1 Operon 432 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 914440 9726972 SPAP_0957 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876548.1 913769 D 574093 CDS YP_003876549.1 307067583 9726973 complement(914491..914688) 1 NC_014494.1 Operon 433 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein 914688 9726973 SPAP_0958 Streptococcus pneumoniae AP200 AraC-type DNA-binding domain-containing protein YP_003876549.1 914491 R 574093 CDS YP_003876550.1 307067584 9726974 914681..915589 1 NC_014494.1 Operon 434 Gene 1 COG0583 Transcriptional regulator; transcriptional regulator 915589 9726974 SPAP_0959 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876550.1 914681 D 574093 CDS YP_003876551.1 307067585 9726975 915586..916047 1 NC_014494.1 Operon 434 Gene 2 COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase 916047 9726975 SPAP_0960 Streptococcus pneumoniae AP200 lipoprotein signal peptidase YP_003876551.1 915586 D 574093 CDS YP_003876552.1 307067586 9726976 916037..916924 1 NC_014494.1 Operon 434 Gene 3 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 916924 9726976 SPAP_0961 Streptococcus pneumoniae AP200 23S RNA-specific pseudouridylate synthase YP_003876552.1 916037 D 574093 CDS YP_003876553.1 307067587 9726977 916927..918822 1 NC_014494.1 Operon 434 Gene 4 COG5263 FOG: Choline binding protein E CbpE; choline binding protein E CbpE 918822 9726977 SPAP_0962 Streptococcus pneumoniae AP200 choline binding protein E CbpE YP_003876553.1 916927 D 574093 CDS YP_003876554.1 307067588 9726978 918923..920032 1 NC_014494.1 Operon 435 Gene 1 COG0263 Glutamate 5-kinase; glutamate 5-kinase 920032 9726978 SPAP_0963 Streptococcus pneumoniae AP200 glutamate 5-kinase YP_003876554.1 918923 D 574093 CDS YP_003876555.1 307067589 9726979 920042..921304 1 NC_014494.1 Operon 435 Gene 2 COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase 921304 9726979 SPAP_0964 Streptococcus pneumoniae AP200 gamma-glutamyl phosphate reductase YP_003876555.1 920042 D 574093 CDS YP_003876556.1 307067590 9726980 921308..922105 1 NC_014494.1 Operon 435 Gene 3 COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 922105 9726980 SPAP_0965 Streptococcus pneumoniae AP200 pyrroline-5-carboxylate reductase YP_003876556.1 921308 D 574093 CDS YP_003876557.1 307067591 9726981 922325..922963 1 NC_014494.1 Operon 436 Gene 1 COG0125 Thymidylate kinase; thymidylate kinase 922963 9726981 SPAP_0966 Streptococcus pneumoniae AP200 thymidylate kinase YP_003876557.1 922325 D 574093 CDS YP_003876558.1 307067592 9726982 922960..923850 1 NC_014494.1 Operon 436 Gene 2 COG0470 ATPase involved in DNA replication; DNA replication ATPase 923850 9726982 SPAP_0967 Streptococcus pneumoniae AP200 DNA replication ATPase YP_003876558.1 922960 D 574093 CDS YP_003876559.1 307067593 9726983 923890..924207 1 NC_014494.1 Operon 436 Gene 3 COG4467 Uncharacterized protein conserved in bacteria; hypothetical protein 924207 9726983 SPAP_0968 Streptococcus pneumoniae AP200 hypothetical protein YP_003876559.1 923890 D 574093 CDS YP_003876560.1 307067594 9726984 924210..925079 1 NC_014494.1 Operon 436 Gene 4 COG0313 Predicted methyltransferases; putative methyltransferase 925079 9726984 SPAP_0969 Streptococcus pneumoniae AP200 putative methyltransferase YP_003876560.1 924210 D 574093 CDS YP_003876561.1 307067595 9726985 925306..925824 1 NC_014494.1 Operon 437 Gene 1 COG4283 Uncharacterized conserved protein; hypothetical protein 925824 9726985 SPAP_0970 Streptococcus pneumoniae AP200 hypothetical protein YP_003876561.1 925306 D 574093 CDS YP_003876562.1 307067596 9726986 925933..926070 1 NC_014494.1 Operon 438 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 926070 9726986 SPAP_0971 Streptococcus pneumoniae AP200 hypothetical protein YP_003876562.1 925933 D 574093 CDS YP_003876563.1 307067597 9726987 926077..926577 1 NC_014494.1 Operon 438 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 926577 9726987 SPAP_0972 Streptococcus pneumoniae AP200 hypothetical protein YP_003876563.1 926077 D 574093 CDS YP_003876564.1 307067598 9726988 complement(926574..926963) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 926963 9726988 SPAP_0973 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876564.1 926574 R 574093 CDS YP_003876565.1 307067599 9726989 complement(927048..927383) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 927383 9726989 SPAP_0974 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876565.1 927048 R 574093 CDS YP_003876566.1 307067600 9726990 927877..929211 1 NC_014494.1 Operon 440 Gene 1 COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; NAD(FAD)-utilizing enzyme possibly involved in translation 929211 9726990 SPAP_0975 Streptococcus pneumoniae AP200 NAD(FAD)-utilizing enzyme possibly involved in translation YP_003876566.1 927877 D 574093 CDS YP_003876567.1 307067601 9726991 929295..930032 1 NC_014494.1 Operon 440 Gene 2 COG0528 Uridylate kinase; Uridylate kinase 930032 9726991 SPAP_0976 Streptococcus pneumoniae AP200 Uridylate kinase YP_003876567.1 929295 D 574093 CDS YP_003876568.1 307067602 9726992 930041..930598 1 NC_014494.1 Operon 440 Gene 3 COG0233 Ribosome recycling factor; ribosome recycling factor 930598 9726992 SPAP_0977 Streptococcus pneumoniae AP200 ribosome recycling factor YP_003876568.1 930041 D 574093 CDS YP_003876569.1 307067603 9726993 930619..931512 1 NC_014494.1 Operon 440 Gene 4 COG2996 Uncharacterized protein conserved in bacteria; hypothetical protein 931512 9726993 SPAP_0978 Streptococcus pneumoniae AP200 hypothetical protein YP_003876569.1 930619 D 574093 CDS YP_003876570.1 307067604 9726994 931548..931736 1 NC_014494.1 Operon 440 Gene 5 COG4479 Uncharacterized protein conserved in bacteria; hypothetical protein 931736 9726994 SPAP_0979 Streptococcus pneumoniae AP200 hypothetical protein YP_003876570.1 931548 D 574093 CDS YP_003876571.1 307067605 9726995 931822..932790 1 NC_014494.1 Operon 441 Gene 1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; phosphate starvation-inducible protein PhoH 932790 9726995 SPAP_0980 Streptococcus pneumoniae AP200 phosphate starvation-inducible protein PhoH YP_003876571.1 931822 D 574093 CDS YP_003876572.1 307067606 9726996 932983..933483 1 NC_014494.1 Operon 442 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 933483 9726996 SPAP_0981 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003876572.1 932983 D 574093 CDS YP_003876573.1 307067607 9726997 933486..933713 1 NC_014494.1 Operon 442 Gene 2 COG3070 Regulator of competence-specific genes; regulator of competence-specific genes 933713 9726997 SPAP_0982 Streptococcus pneumoniae AP200 regulator of competence-specific genes YP_003876573.1 933486 D 574093 CDS YP_003876574.1 307067608 9726998 complement(934113..934388) 1 NC_014494.1 Operon 443 Gene 1 COG0686 Alanine dehydrogenase; alanine dehydrogenase 934388 9726998 SPAP_0983 Streptococcus pneumoniae AP200 alanine dehydrogenase YP_003876574.1 934113 R 574093 CDS YP_003876575.1 307067609 9726999 complement(934385..934573) 1 NC_014494.1 Operon 443 Gene 2 COG0686 Alanine dehydrogenase; alanine dehydrogenase 934573 9726999 SPAP_0984 Streptococcus pneumoniae AP200 alanine dehydrogenase YP_003876575.1 934385 R 574093 CDS YP_003876576.1 307067610 9727000 complement(934799..935224) 1 NC_014494.1 Operon 444 Gene 1 COG0686 Alanine dehydrogenase; alanine dehydrogenase 935224 9727000 SPAP_0985 Streptococcus pneumoniae AP200 alanine dehydrogenase YP_003876576.1 934799 R 574093 CDS YP_003876577.1 307067611 9727001 935401..935970 1 NC_014494.1 Operon 445 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 935970 9727001 SPAP_0986 Streptococcus pneumoniae AP200 acetyltransferase YP_003876577.1 935401 D 574093 CDS YP_003876578.1 307067612 9727002 936038..936688 1 NC_014494.1 Operon 445 Gene 2 COG1555 DNA uptake protein and related DNA-binding proteins; DNA uptake protein-like DNA-binding protein 936688 9727002 SPAP_0987 Streptococcus pneumoniae AP200 DNA uptake protein-like DNA-binding protein YP_003876578.1 936038 D 574093 CDS YP_003876579.1 307067613 9727003 936672..938912 1 NC_014494.1 Operon 445 Gene 3 COG0658 Predicted membrane metal-binding protein; putative membrane metal-binding protein 938912 9727003 SPAP_0988 Streptococcus pneumoniae AP200 putative membrane metal-binding protein YP_003876579.1 936672 D 574093 CDS YP_003876580.1 307067614 9727004 939311..939898 1 NC_014494.1 Operon 446 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 939898 9727004 SPAP_0989 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003876580.1 939311 D 574093 CDS YP_003876581.1 307067615 9727005 939902..941083 1 NC_014494.1 Operon 446 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 941083 9727005 SPAP_0990 Streptococcus pneumoniae AP200 hypothetical protein YP_003876581.1 939902 D 574093 CDS YP_003876582.1 307067616 9727006 941390..941920 1 NC_014494.1 Operon 447 Gene 1 protein supported gi|163801060|ref|ZP_02194960.1| 50S ribosomal protein L35; hypothetical protein 941920 9727006 SPAP_0991 Streptococcus pneumoniae AP200 hypothetical protein YP_003876582.1 941390 D 574093 CDS YP_003876583.1 307067617 9727007 941953..942153 1 NC_014494.1 Operon 447 Gene 2 protein supported gi|15900837|ref|NP_345441.1| 50S ribosomal protein L35; hypothetical protein 942153 9727007 SPAP_0992 Streptococcus pneumoniae AP200 hypothetical protein YP_003876583.1 941953 D 574093 CDS YP_003876584.1 307067618 9727008 942205..942564 1 NC_014494.1 Operon 447 Gene 3 protein supported gi|15900838|ref|NP_345442.1| 50S ribosomal protein L20; hypothetical protein 942564 9727008 SPAP_0993 Streptococcus pneumoniae AP200 hypothetical protein YP_003876584.1 942205 D 574093 CDS YP_003876585.1 307067619 9727009 942622..943002 1 NC_014494.1 Operon 447 Gene 4 protein supported gi|15900839|ref|NP_345443.1| lactoylglutathione lyase; hypothetical protein 943002 9727009 SPAP_0994 Streptococcus pneumoniae AP200 hypothetical protein YP_003876585.1 942622 D 574093 CDS YP_003876586.1 307067620 9727010 943252..944052 1 NC_014494.1 Operon 448 Gene 1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; 2-polyprenylphenol 6-hydroxylase 944052 9727010 SPAP_0995 Streptococcus pneumoniae AP200 2-polyprenylphenol 6-hydroxylase YP_003876586.1 943252 D 574093 CDS YP_003876587.1 307067621 9727011 944063..945001 1 NC_014494.1 Operon 448 Gene 2 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 945001 9727011 SPAP_0996 Streptococcus pneumoniae AP200 dihydroorotate dehydrogenase YP_003876587.1 944063 D 574093 CDS YP_003876588.1 307067622 9727012 945100..946944 1 NC_014494.1 Operon 448 Gene 3 COG5263 FOG: endo-beta-N-acetylglucosaminidase LytB; endo-beta-N-acetylglucosaminidase LytB 946944 9727012 SPAP_0997 Streptococcus pneumoniae AP200 endo-beta-N-acetylglucosaminidase LytB YP_003876588.1 945100 D 574093 CDS YP_003876589.1 307067623 9727013 complement(947005..948660) 1 NC_014494.1 Operon 449 Gene 1 COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; putative RNA-binding protein 948660 9727013 SPAP_0998 Streptococcus pneumoniae AP200 putative RNA-binding protein YP_003876589.1 947005 R 574093 CDS YP_003876590.1 307067624 9727014 948765..949262 1 NC_014494.1 Operon 450 Gene 1 COG0319 Predicted metal-dependent hydrolase; putative metal-dependent hydrolase 949262 9727014 SPAP_0999 Streptococcus pneumoniae AP200 putative metal-dependent hydrolase YP_003876590.1 948765 D 574093 CDS YP_003876591.1 307067625 9727015 949243..949638 1 NC_014494.1 Operon 450 Gene 2 COG0818 Diacylglycerol kinase; diacylglycerol kinase 949638 9727015 SPAP_1000 Streptococcus pneumoniae AP200 diacylglycerol kinase YP_003876591.1 949243 D 574093 CDS YP_003876592.1 307067626 9727016 949655..950554 1 NC_014494.1 Operon 450 Gene 3 COG1159 GTPase; GTPase 950554 9727016 SPAP_1001 Streptococcus pneumoniae AP200 GTPase YP_003876592.1 949655 D 574093 CDS YP_003876593.1 307067627 9727017 950603..951427 1 NC_014494.1 Operon 450 Gene 4 COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase 951427 9727017 SPAP_1002 Streptococcus pneumoniae AP200 formamidopyrimidine-DNA glycosylase YP_003876593.1 950603 D 574093 CDS YP_003876594.1 307067628 9727018 951427..952032 1 NC_014494.1 Operon 450 Gene 5 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 952032 9727018 SPAP_1003 Streptococcus pneumoniae AP200 dephospho-CoA kinase YP_003876594.1 951427 D 574093 CDS YP_003876595.1 307067629 9727019 complement(951916..952116) 1 NC_014494.1 Operon 451 Gene 1 protein supported gi|15902918|ref|NP_358468.1| hypothetical protein spr0874; hypothetical protein 952116 9727019 SPAP_1004 Streptococcus pneumoniae AP200 hypothetical protein YP_003876595.1 951916 R 574093 CDS YP_003876596.1 307067630 9727020 952019..953218 1 NC_014494.1 Operon 452 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 953218 9727020 SPAP_1005 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003876596.1 952019 D 574093 CDS YP_003876597.1 307067631 9727021 953218..953367 1 NC_014494.1 Operon 452 Gene 2 protein supported gi|15902920|ref|NP_358470.1| 50S ribosomal protein L33; hypothetical protein 953367 9727021 SPAP_1006 Streptococcus pneumoniae AP200 hypothetical protein YP_003876597.1 953218 D 574093 CDS YP_003876598.1 307067632 9727022 953407..953640 1 NC_014494.1 Operon 452 Gene 3 COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 953640 9727022 SPAP_1007 Streptococcus pneumoniae AP200 preprotein translocase subunit SecG YP_003876598.1 953407 D 574093 CDS YP_003876599.1 307067633 9727023 953742..956096 1 NC_014494.1 Operon 453 Gene 1 COG0557 Exoribonuclease R; exoribonuclease R 956096 9727023 SPAP_1008 Streptococcus pneumoniae AP200 exoribonuclease R YP_003876599.1 953742 D 574093 CDS YP_003876600.1 307067634 9727024 956059..956526 1 NC_014494.1 Operon 453 Gene 2 COG0691 tmRNA-binding protein; tmRNA-binding protein 956526 9727024 SPAP_1009 Streptococcus pneumoniae AP200 tmRNA-binding protein YP_003876600.1 956059 D 574093 CDS YP_003876601.1 307067635 9727025 956542..957402 1 NC_014494.1 Operon 453 Gene 3 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 957402 9727025 SPAP_1010 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003876601.1 956542 D 574093 CDS YP_003876602.1 307067636 9727026 957475..958428 1 NC_014494.1 Operon 454 Gene 1 COG4469 Competence protein; competence protein 958428 9727026 SPAP_1011 Streptococcus pneumoniae AP200 competence protein YP_003876602.1 957475 D 574093 CDS YP_003876603.1 307067637 9727027 958447..960249 1 NC_014494.1 Operon 454 Gene 2 COG1164 Oligoendopeptidase F; oligoendopeptidase F 960249 9727027 SPAP_1012 Streptococcus pneumoniae AP200 oligoendopeptidase F YP_003876603.1 958447 D 574093 CDS YP_003876604.1 307067638 9727028 960251..960964 1 NC_014494.1 Operon 454 Gene 3 COG4122 Predicted O-methyltransferase; putative O-methyltransferase 960964 9727028 SPAP_1013 Streptococcus pneumoniae AP200 putative O-methyltransferase YP_003876604.1 960251 D 574093 CDS YP_003876605.1 307067639 9727029 961031..961348 1 NC_014494.1 Operon 454 Gene 4 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961348 9727029 SPAP_1014 Streptococcus pneumoniae AP200 parvulin-like peptidyl-prolyl isomerase YP_003876605.1 961031 D 574093 CDS YP_003876606.1 307067640 9727030 961239..961619 1 NC_014494.1 Operon 454 Gene 5 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961619 9727030 SPAP_1015 Streptococcus pneumoniae AP200 parvulin-like peptidyl-prolyl isomerase YP_003876606.1 961239 D 574093 CDS YP_003876607.1 307067641 9727031 961675..961974 1 NC_014494.1 Operon 454 Gene 6 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961974 9727031 SPAP_1016 Streptococcus pneumoniae AP200 parvulin-like peptidyl-prolyl isomerase YP_003876607.1 961675 D 574093 CDS YP_003876608.1 307067642 9727032 complement(962093..962434) 1 NC_014494.1 Operon 455 Gene 1 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 962434 9727032 SPAP_1017 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876608.1 962093 R 574093 CDS YP_003876609.1 307067643 9727033 complement(962434..962625) 1 NC_014494.1 Operon 455 Gene 2 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 962625 9727033 SPAP_1018 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876609.1 962434 R 574093 CDS YP_003876610.1 307067644 9727034 complement(962714..962944) 1 NC_014494.1 Operon 456 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 962944 9727034 SPAP_1019 Streptococcus pneumoniae AP200 hypothetical protein YP_003876610.1 962714 R 574093 CDS YP_003876611.1 307067645 9727035 complement(963196..963816) 1 NC_014494.1 Operon 457 Gene 1 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 963816 9727035 SPAP_1020 Streptococcus pneumoniae AP200 fructose-2,6-bisphosphatase YP_003876611.1 963196 R 574093 CDS YP_003876612.1 307067646 9727036 complement(963816..964298) 1 NC_014494.1 Operon 457 Gene 2 COG2606 Uncharacterized conserved protein; hypothetical protein 964298 9727036 SPAP_1021 Streptococcus pneumoniae AP200 hypothetical protein YP_003876612.1 963816 R 574093 CDS YP_003876613.1 307067647 9727037 complement(964298..965140) 1 NC_014494.1 Operon 457 Gene 3 COG2035 Predicted membrane protein; hypothetical protein 965140 9727037 SPAP_1022 Streptococcus pneumoniae AP200 hypothetical protein YP_003876613.1 964298 R 574093 CDS YP_003876614.1 307067648 9727038 complement(965235..966035) 1 NC_014494.1 Operon 457 Gene 4 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); lyzozyme M1 (1,4-beta-N-acetylmuramidase) 966035 9727038 SPAP_1023 Streptococcus pneumoniae AP200 lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_003876614.1 965235 R 574093 CDS YP_003876615.1 307067649 9727039 966179..967558 1 NC_014494.1 Operon 458 Gene 1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); N-acetylglucosamine-1-phosphate uridyltransferase 967558 9727039 SPAP_1024 Streptococcus pneumoniae AP200 N-acetylglucosamine-1-phosphate uridyltransferase YP_003876615.1 966179 D 574093 CDS YP_003876616.1 307067650 9727040 967568..968113 1 NC_014494.1 Operon 458 Gene 2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 968113 9727040 SPAP_1025 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876616.1 967568 D 574093 CDS YP_003876617.1 307067651 9727041 968125..968439 1 NC_014494.1 Operon 458 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 968439 9727041 SPAP_1026 Streptococcus pneumoniae AP200 hypothetical protein YP_003876617.1 968125 D 574093 CDS YP_003876618.1 307067652 9727042 968456..969148 1 NC_014494.1 Operon 458 Gene 4 COG0775 Nucleoside phosphorylase; nucleoside phosphorylase 969148 9727042 SPAP_1027 Streptococcus pneumoniae AP200 nucleoside phosphorylase YP_003876618.1 968456 D 574093 CDS YP_003876619.1 307067653 9727043 969225..969716 1 NC_014494.1 Operon 458 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 969716 9727043 SPAP_1028 Streptococcus pneumoniae AP200 hypothetical protein YP_003876619.1 969225 D 574093 CDS YP_003876620.1 307067654 9727044 969814..970404 1 NC_014494.1 Operon 459 Gene 1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon-like 3'-5' exonuclease 970404 9727044 SPAP_1029 Streptococcus pneumoniae AP200 DNA polymerase III subunit epsilon-like 3'-5' exonuclease YP_003876620.1 969814 D 574093 CDS YP_003876621.1 307067655 9727045 970413..972176 1 NC_014494.1 Operon 459 Gene 2 COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 972176 9727045 SPAP_1030 Streptococcus pneumoniae AP200 glycerophosphoryl diester phosphodiesterase YP_003876621.1 970413 D 574093 CDS YP_003876622.1 307067656 9727046 972372..972755 1 NC_014494.1 transposase-like protein, IS630 972755 9727046 SPAP_1031 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003876622.1 972372 D 574093 CDS YP_003876623.1 307067657 9727047 complement(972761..973021) 1 NC_014494.1 Operon 461 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 973021 9727047 SPAP_1032 Streptococcus pneumoniae AP200 hypothetical protein YP_003876623.1 972761 R 574093 CDS YP_003876624.1 307067658 9727048 973202..973402 1 NC_014494.1 Operon 462 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 973402 9727048 SPAP_1033 Streptococcus pneumoniae AP200 hypothetical protein YP_003876624.1 973202 D 574093 CDS YP_003876625.1 307067659 9727049 973439..973843 1 NC_014494.1 Operon 462 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 973843 9727049 SPAP_1034 Streptococcus pneumoniae AP200 hypothetical protein YP_003876625.1 973439 D 574093 CDS YP_003876626.1 307067660 9727050 974208..974780 1 NC_014494.1 Operon 463 Gene 1 COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 974780 9727050 SPAP_1035 Streptococcus pneumoniae AP200 cytochrome c biogenesis protein YP_003876626.1 974208 D 574093 CDS YP_003876627.1 307067661 9727051 974791..975348 1 NC_014494.1 Operon 463 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 975348 9727051 SPAP_1036 Streptococcus pneumoniae AP200 thiol-disulfide isomerase and thioredoxin YP_003876627.1 974791 D 574093 CDS YP_003876628.1 307067662 9727052 975722..977113 1 NC_014494.1 Operon 464 Gene 1 COG0531 Amino acid transporters; amino acid transporter 977113 9727052 SPAP_1037 Streptococcus pneumoniae AP200 amino acid transporter YP_003876628.1 975722 D 574093 CDS YP_003876629.1 307067663 9727053 977256..978173 1 NC_014494.1 Operon 465 Gene 1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin 978173 9727053 SPAP_1038 Streptococcus pneumoniae AP200 metal ion ABC transporter periplasmic protein/surface adhesin YP_003876629.1 977256 D 574093 CDS YP_003876630.1 307067664 9727054 978181..979050 1 NC_014494.1 Operon 465 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 979050 9727054 SPAP_1039 Streptococcus pneumoniae AP200 hypothetical protein YP_003876630.1 978181 D 574093 CDS YP_003876631.1 307067665 9727055 979017..979736 1 NC_014494.1 Operon 465 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 979736 9727055 SPAP_1040 Streptococcus pneumoniae AP200 hypothetical protein YP_003876631.1 979017 D 574093 CDS YP_003876632.1 307067666 9727056 979724..980659 1 NC_014494.1 Operon 465 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 980659 9727056 SPAP_1041 Streptococcus pneumoniae AP200 hypothetical protein YP_003876632.1 979724 D 574093 CDS YP_003876633.1 307067667 9727057 981081..981461 1 NC_014494.1 Operon 466 Gene 1 COG3412 Uncharacterized protein conserved in bacteria; hypothetical protein 981461 9727057 SPAP_1042 Streptococcus pneumoniae AP200 hypothetical protein YP_003876633.1 981081 D 574093 CDS YP_003876634.1 307067668 9727058 981920..982633 1 NC_014494.1 Operon 467 Gene 1 COG1011 Predicted hydrolase (HAD superfamily); putative HD superfamily hydrolase 982633 9727058 SPAP_1043 Streptococcus pneumoniae AP200 putative HD superfamily hydrolase YP_003876634.1 981920 D 574093 CDS YP_003876635.1 307067669 9727059 982691..983293 1 NC_014494.1 Operon 467 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 983293 9727059 SPAP_1044 Streptococcus pneumoniae AP200 hypothetical protein YP_003876635.1 982691 D 574093 CDS YP_003876636.1 307067670 9727060 983429..984082 1 NC_014494.1 Operon 468 Gene 1 COG0692 Uracil DNA glycosylase; Uracil DNA glycosylase 984082 9727060 SPAP_1045 Streptococcus pneumoniae AP200 Uracil DNA glycosylase YP_003876636.1 983429 D 574093 CDS YP_003876637.1 307067671 9727061 984092..984556 1 NC_014494.1 Operon 468 Gene 2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 984556 9727061 SPAP_1046 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876637.1 984092 D 574093 CDS YP_003876638.1 307067672 9727062 984569..985837 1 NC_014494.1 Operon 468 Gene 3 COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase-like cyclic amidohydrolase 985837 9727062 SPAP_1047 Streptococcus pneumoniae AP200 dihydroorotase-like cyclic amidohydrolase YP_003876638.1 984569 D 574093 CDS YP_003876639.1 307067673 9727063 985851..986111 1 NC_014494.1 Operon 468 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 986111 9727063 SPAP_1048 Streptococcus pneumoniae AP200 hypothetical protein YP_003876639.1 985851 D 574093 CDS YP_003876640.1 307067674 9727064 986122..987483 1 NC_014494.1 Operon 468 Gene 5 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 987483 9727064 SPAP_1049 Streptococcus pneumoniae AP200 Na+-driven multidrug efflux pump YP_003876640.1 986122 D 574093 CDS YP_003876641.1 307067675 9727065 987637..988605 1 NC_014494.1 Operon 469 Gene 1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit alpha 988605 9727065 SPAP_1050 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit alpha YP_003876641.1 987637 D 574093 CDS YP_003876642.1 307067676 9727066 988636..989613 1 NC_014494.1 Operon 469 Gene 2 COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit beta 989613 9727066 SPAP_1051 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit beta YP_003876642.1 988636 D 574093 CDS YP_003876643.1 307067677 9727067 989831..990874 1 NC_014494.1 Operon 470 Gene 1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component-like protein 990874 9727067 SPAP_1052 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component-like protein YP_003876643.1 989831 D 574093 CDS YP_003876644.1 307067678 9727068 990920..992623 1 NC_014494.1 Operon 470 Gene 2 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein 992623 9727068 SPAP_1053 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein YP_003876644.1 990920 D 574093 CDS YP_003876645.1 307067679 9727069 992687..993676 1 NC_014494.1 Operon 470 Gene 3 COG0095 Lipoate-protein ligase A; lipoate-protein ligase A 993676 9727069 SPAP_1054 Streptococcus pneumoniae AP200 lipoate-protein ligase A YP_003876645.1 992687 D 574093 CDS YP_003876646.1 307067680 9727070 complement(993749..994819) 1 NC_014494.1 Operon 471 Gene 1 COG0582 Integrase; integrase 994819 9727070 SPAP_1055 Streptococcus pneumoniae AP200 integrase YP_003876646.1 993749 R 574093 CDS YP_003876647.1 307067681 9727071 complement(995403..996953) 1 NC_014494.1 Operon 472 Gene 1 COG0038 Chloride channel protein EriC; chloride channel protein EriC 996953 9727071 SPAP_1056 Streptococcus pneumoniae AP200 chloride channel protein EriC YP_003876647.1 995403 R 574093 CDS YP_003876648.1 307067682 9727072 complement(996969..997748) 1 NC_014494.1 Operon 472 Gene 2 COG0164 Ribonuclease HII; ribonuclease HII 997748 9727072 SPAP_1057 Streptococcus pneumoniae AP200 ribonuclease HII YP_003876648.1 996969 R 574093 CDS YP_003876649.1 307067683 9727073 complement(997735..998586) 1 NC_014494.1 Operon 472 Gene 3 COG1161 Predicted GTPases; putative GTPase 998586 9727073 SPAP_1058 Streptococcus pneumoniae AP200 putative GTPase YP_003876649.1 997735 R 574093 CDS YP_003876650.1 307067684 9727074 complement(999021..1004648) 1 NC_014494.1 immunoglobulin A1 protease; hypothetical protein 1004648 9727074 SPAP_1059 Streptococcus pneumoniae AP200 hypothetical protein YP_003876650.1 999021 R 574093 CDS YP_003876651.1 307067685 9727075 complement(1004857..1006035) 1 NC_014494.1 Operon 474 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1006035 9727075 SPAP_1060 Streptococcus pneumoniae AP200 hypothetical protein YP_003876651.1 1004857 R 574093 CDS YP_003876652.1 307067686 9727076 complement(1006430..1010080) 1 NC_014494.1 Operon 475 Gene 1 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit; contains helicase and exonuclease domains; ATP-dependent exoDNAse (exonuclease V) subunit beta 1010080 9727076 SPAP_1061 Streptococcus pneumoniae AP200 ATP-dependent exoDNAse (exonuclease V) subunit beta YP_003876652.1 1006430 R 574093 CDS YP_003876653.1 307067687 9727077 complement(1010077..1013376) 1 NC_014494.1 Operon 475 Gene 2 COG3857 ATP-dependent nuclease, subunit B; ATP-dependent nuclease subunit B 1013376 9727077 SPAP_1062 Streptococcus pneumoniae AP200 ATP-dependent nuclease subunit B YP_003876653.1 1010077 R 574093 CDS YP_003876654.1 307067688 9727078 1013860..1014207 1 NC_014494.1 transposase-like protein, IS630 1014207 9727078 SPAP_1063 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003876654.1 1013860 D 574093 CDS YP_003876655.1 307067689 9727079 1014542..1014724 1 NC_014494.1 Operon 477 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 1014724 9727079 SPAP_1064 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003876655.1 1014542 D 574093 CDS YP_003876656.1 307067690 9727080 complement(1015208..1016512) 1 NC_014494.1 Operon 478 Gene 1 COG0148 Enolase; enolase 1016512 9727080 SPAP_1065 Streptococcus pneumoniae AP200 enolase YP_003876656.1 1015208 R 574093 CDS YP_003876657.1 307067691 9727081 1016676..1017122 1 NC_014494.1 Operon 479 Gene 1 COG5506 Uncharacterized conserved protein; hypothetical protein 1017122 9727081 SPAP_1066 Streptococcus pneumoniae AP200 hypothetical protein YP_003876657.1 1016676 D 574093 CDS YP_003876658.1 307067692 9727082 complement(1017119..1018234) 1 NC_014494.1 Operon 480 Gene 1 COG1929 Glycerate kinase; glycerate kinase 1018234 9727082 SPAP_1067 Streptococcus pneumoniae AP200 glycerate kinase YP_003876658.1 1017119 R 574093 CDS YP_003876659.1 307067693 9727083 complement(1018243..1018572) 1 NC_014494.1 Operon 480 Gene 2 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase 1018572 9727083 SPAP_1068 Streptococcus pneumoniae AP200 phosphoserine phosphatase YP_003876659.1 1018243 R 574093 CDS YP_003876660.1 307067694 9727084 complement(1018517..1018888) 1 NC_014494.1 Operon 480 Gene 3 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase 1018888 9727084 SPAP_1069 Streptococcus pneumoniae AP200 phosphoserine phosphatase YP_003876660.1 1018517 R 574093 CDS YP_003876661.1 307067695 9727085 complement(1018947..1020380) 1 NC_014494.1 Operon 481 Gene 1 COG0297 Glycogen synthase; glycogen synthase 1020380 9727085 SPAP_1070 Streptococcus pneumoniae AP200 glycogen synthase YP_003876661.1 1018947 R 574093 CDS YP_003876662.1 307067696 9727086 complement(1020377..1021516) 1 NC_014494.1 Operon 481 Gene 2 COG0448 ADP-glucose pyrophosphorylase; ADP-glucose pyrophosphorylase 1021516 9727086 SPAP_1071 Streptococcus pneumoniae AP200 ADP-glucose pyrophosphorylase YP_003876662.1 1020377 R 574093 CDS YP_003876663.1 307067697 9727087 complement(1021506..1022648) 1 NC_014494.1 Operon 481 Gene 3 COG0448 ADP-glucose pyrophosphorylase; ADP-glucose pyrophosphorylase 1022648 9727087 SPAP_1072 Streptococcus pneumoniae AP200 ADP-glucose pyrophosphorylase YP_003876663.1 1021506 R 574093 CDS YP_003876664.1 307067698 9727088 complement(1022638..1024566) 1 NC_014494.1 Operon 481 Gene 4 COG0296 1,4-alpha-glucan branching enzyme; 1,4-alpha-glucan branching enzyme 1024566 9727088 SPAP_1073 Streptococcus pneumoniae AP200 1,4-alpha-glucan branching enzyme YP_003876664.1 1022638 R 574093 CDS YP_003876665.1 307067699 9727089 complement(1024942..1026366) 1 NC_014494.1 Operon 482 Gene 1 COG1012 NAD-dependent aldehyde dehydrogenases; NAD-dependent aldehyde dehydrogenase 1026366 9727089 SPAP_1074 Streptococcus pneumoniae AP200 NAD-dependent aldehyde dehydrogenase YP_003876665.1 1024942 R 574093 CDS YP_003876666.1 307067700 9727090 complement(1026911..1029190) 1 NC_014494.1 Operon 483 Gene 1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; type II secretory pathway pullulanase PulA-like glycosidase 1029190 9727090 SPAP_1075 Streptococcus pneumoniae AP200 type II secretory pathway pullulanase PulA-like glycosidase YP_003876666.1 1026911 R 574093 CDS YP_003876667.1 307067701 9727091 complement(1029302..1031248) 1 NC_014494.1 Operon 483 Gene 2 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase (contains BRCT domain type II) 1031248 9727091 SPAP_1076 Streptococcus pneumoniae AP200 NAD-dependent DNA ligase (contains BRCT domain type II) YP_003876667.1 1029302 R 574093 CDS YP_003876668.1 307067702 9727092 complement(1031353..1032531) 1 NC_014494.1 Operon 484 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 1032531 9727092 SPAP_1077 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003876668.1 1031353 R 574093 CDS YP_003876669.1 307067703 9727093 complement(1032611..1033474) 1 NC_014494.1 Operon 484 Gene 2 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1033474 9727093 SPAP_1078 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876669.1 1032611 R 574093 CDS YP_003876670.1 307067704 9727094 complement(1033477..1035378) 1 NC_014494.1 Operon 484 Gene 3 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 1035378 9727094 SPAP_1079 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876670.1 1033477 R 574093 CDS YP_003876671.1 307067705 9727095 complement(1035803..1036078) 1 NC_014494.1 Operon 485 Gene 1 COG0776 Bacterial nucleoid DNA-binding protein; nucleoid DNA-binding protein 1036078 9727095 SPAP_1080 Streptococcus pneumoniae AP200 nucleoid DNA-binding protein YP_003876671.1 1035803 R 574093 CDS YP_003876672.1 307067706 9727096 complement(1036184..1037023) 1 NC_014494.1 Operon 485 Gene 2 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein 1037023 9727096 SPAP_1081 Streptococcus pneumoniae AP200 hypothetical protein YP_003876672.1 1036184 R 574093 CDS YP_003876673.1 307067707 9727097 1037165..1038013 1 NC_014494.1 Operon 486 Gene 1 COG1284 Uncharacterized conserved protein; hypothetical protein 1038013 9727097 SPAP_1082 Streptococcus pneumoniae AP200 hypothetical protein YP_003876673.1 1037165 D 574093 CDS YP_003876674.1 307067708 9727098 complement(1038106..1039023) 1 NC_014494.1 Operon 487 Gene 1 COG0196 FAD synthase; FAD synthase 1039023 9727098 SPAP_1083 Streptococcus pneumoniae AP200 FAD synthase YP_003876674.1 1038106 R 574093 CDS YP_003876675.1 307067709 9727099 complement(1039312..1039482) 1 NC_014494.1 Operon 488 Gene 1 protein supported gi|148998378|ref|ZP_01825820.1| 50S ribosomal protein L21; hypothetical protein 1039482 9727099 SPAP_1084 Streptococcus pneumoniae AP200 hypothetical protein YP_003876675.1 1039312 R 574093 CDS YP_003876676.1 307067710 9727100 1039458..1039664 1 NC_014494.1 Operon 489 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1039664 9727100 SPAP_1085 Streptococcus pneumoniae AP200 hypothetical protein YP_003876676.1 1039458 D 574093 CDS YP_003876677.1 307067711 9727101 complement(1039975..1040268) 1 NC_014494.1 Operon 490 Gene 1 protein supported gi|111658016|ref|ZP_01408720.1| hypothetical protein SpneT_02000813; hypothetical protein 1040268 9727101 SPAP_1086 Streptococcus pneumoniae AP200 hypothetical protein YP_003876677.1 1039975 R 574093 CDS YP_003876678.1 307067712 9727102 complement(1040285..1040629) 1 NC_014494.1 Operon 490 Gene 2 protein supported gi|15900973|ref|NP_345577.1| hypothetical protein SP_1106; hypothetical protein 1040629 9727102 SPAP_1087 Streptococcus pneumoniae AP200 hypothetical protein YP_003876678.1 1040285 R 574093 CDS YP_003876679.1 307067713 9727103 complement(1040645..1040959) 1 NC_014494.1 Operon 490 Gene 3 protein supported gi|148985076|ref|ZP_01818319.1| ribosomal protein L21; hypothetical protein 1040959 9727103 SPAP_1088 Streptococcus pneumoniae AP200 hypothetical protein YP_003876679.1 1040645 R 574093 CDS YP_003876680.1 307067714 9727104 complement(1041178..1041846) 1 NC_014494.1 Operon 491 Gene 1 COG3619 Predicted membrane protein; hypothetical protein 1041846 9727104 SPAP_1089 Streptococcus pneumoniae AP200 hypothetical protein YP_003876680.1 1041178 R 574093 CDS YP_003876681.1 307067715 9727105 1042248..1042547 1 NC_014494.1 Operon 492 Gene 1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 1042547 9727105 SPAP_1090 Streptococcus pneumoniae AP200 hypothetical protein YP_003876681.1 1042248 D 574093 CDS YP_003876682.1 307067716 9727106 1042729..1043247 1 NC_014494.1 Operon 493 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 1043247 9727106 SPAP_1091 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876682.1 1042729 D 574093 CDS YP_003876683.1 307067717 9727107 1043528..1044055 1 NC_014494.1 Operon 494 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 1044055 9727107 SPAP_1092 Streptococcus pneumoniae AP200 transposase-like protein, IS1167 YP_003876683.1 1043528 D 574093 CDS YP_003876684.1 307067718 9727108 complement(1044316..1045290) 1 NC_014494.1 Operon 495 Gene 1 COG0280 Phosphotransacetylase; phosphotransacetylase 1045290 9727108 SPAP_1093 Streptococcus pneumoniae AP200 phosphotransacetylase YP_003876684.1 1044316 R 574093 CDS YP_003876685.1 307067719 9727109 complement(1045334..1046230) 1 NC_014494.1 Operon 495 Gene 2 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 1046230 9727109 SPAP_1094 Streptococcus pneumoniae AP200 23S RNA-specific pseudouridylate synthase YP_003876685.1 1045334 R 574093 CDS YP_003876686.1 307067720 9727110 complement(1046227..1047057) 1 NC_014494.1 Operon 495 Gene 3 COG0061 Predicted sugar kinase; putative sugar kinase 1047057 9727110 SPAP_1095 Streptococcus pneumoniae AP200 putative sugar kinase YP_003876686.1 1046227 R 574093 CDS YP_003876687.1 307067721 9727111 complement(1047029..1047700) 1 NC_014494.1 Operon 495 Gene 4 COG2357 Uncharacterized protein conserved in bacteria; hypothetical protein 1047700 9727111 SPAP_1096 Streptococcus pneumoniae AP200 hypothetical protein YP_003876687.1 1047029 R 574093 CDS YP_003876688.1 307067722 9727112 1047828..1048397 1 NC_014494.1 Operon 496 Gene 1 COG4116 Uncharacterized protein conserved in bacteria; hypothetical protein 1048397 9727112 SPAP_1097 Streptococcus pneumoniae AP200 hypothetical protein YP_003876688.1 1047828 D 574093 CDS YP_003876689.1 307067723 9727113 1048510..1049469 1 NC_014494.1 Operon 497 Gene 1 COG0462 Phosphoribosylpyrophosphate synthetase; phosphoribosylpyrophosphate synthetase 1049469 9727113 SPAP_1098 Streptococcus pneumoniae AP200 phosphoribosylpyrophosphate synthetase YP_003876689.1 1048510 D 574093 CDS YP_003876690.1 307067724 9727114 1049479..1050594 1 NC_014494.1 Operon 497 Gene 2 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine sulfinate desulfinase/cysteine desulfurase-like protein 1050594 9727114 SPAP_1099 Streptococcus pneumoniae AP200 cysteine sulfinate desulfinase/cysteine desulfurase-like protein YP_003876690.1 1049479 D 574093 CDS YP_003876691.1 307067725 9727115 1050599..1050946 1 NC_014494.1 Operon 497 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1050946 9727115 SPAP_1100 Streptococcus pneumoniae AP200 hypothetical protein YP_003876691.1 1050599 D 574093 CDS YP_003876692.1 307067726 9727116 1050954..1051169 1 NC_014494.1 Operon 497 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1051169 9727116 SPAP_1101 Streptococcus pneumoniae AP200 hypothetical protein YP_003876692.1 1050954 D 574093 CDS YP_003876693.1 307067727 9727117 1051252..1051893 1 NC_014494.1 Operon 498 Gene 1 COG2344 AT-rich DNA-binding protein; AT-rich DNA-binding protein 1051893 9727117 SPAP_1102 Streptococcus pneumoniae AP200 AT-rich DNA-binding protein YP_003876693.1 1051252 D 574093 CDS YP_003876694.1 307067728 9727118 1051911..1052600 1 NC_014494.1 Operon 498 Gene 2 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase 1052600 9727118 SPAP_1103 Streptococcus pneumoniae AP200 putative glutamine amidotransferase YP_003876694.1 1051911 D 574093 CDS YP_003876695.1 307067729 9727119 complement(1052597..1053277) 1 NC_014494.1 Operon 499 Gene 1 COG2003 DNA repair proteins; DNA repair protein 1053277 9727119 SPAP_1104 Streptococcus pneumoniae AP200 DNA repair protein YP_003876695.1 1052597 R 574093 CDS YP_003876696.1 307067730 9727120 complement(1053320..1055611) 1 NC_014494.1 Operon 499 Gene 2 COG0210 Superfamily I DNA and RNA helicases; superfamily I DNA and RNA helicase 1055611 9727120 SPAP_1105 Streptococcus pneumoniae AP200 superfamily I DNA and RNA helicase YP_003876696.1 1053320 R 574093 CDS YP_003876697.1 307067731 9727121 complement(1055783..1056268) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1056268 9727121 SPAP_1106 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876697.1 1055783 R 574093 CDS YP_003876698.1 307067732 9727122 complement(1056210..1056764) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1056764 9727122 SPAP_1107 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876698.1 1056210 R 574093 CDS YP_003876699.1 307067733 9727123 complement(1056989..1057849) 1 NC_014494.1 Operon 501 Gene 1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 1057849 9727123 SPAP_1108 Streptococcus pneumoniae AP200 methionine aminopeptidase YP_003876699.1 1056989 R 574093 CDS YP_003876700.1 307067734 9727124 complement(1057865..1059142) 1 NC_014494.1 Operon 501 Gene 2 COG4109 Predicted transcriptional regulator containing CBS domains; putative transcriptional regulator 1059142 9727124 SPAP_1109 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876700.1 1057865 R 574093 CDS YP_003876701.1 307067735 9727125 complement(1059135..1059686) 1 NC_014494.1 Operon 501 Gene 3 protein supported gi|116628248|ref|YP_820867.1| GNAT family acetyltransferase; hypothetical protein 1059686 9727125 SPAP_1110 Streptococcus pneumoniae AP200 hypothetical protein YP_003876701.1 1059135 R 574093 CDS YP_003876702.1 307067736 9727126 complement(1059702..1060961) 1 NC_014494.1 Operon 501 Gene 4 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine enolpyruvyl transferase 1060961 9727126 SPAP_1111 Streptococcus pneumoniae AP200 UDP-N-acetylglucosamine enolpyruvyl transferase YP_003876702.1 1059702 R 574093 CDS YP_003876703.1 307067737 9727127 1061104..1061229 1 NC_014494.1 Operon 502 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1061229 9727127 SPAP_1112 Streptococcus pneumoniae AP200 hypothetical protein YP_003876703.1 1061104 D 574093 CDS YP_003876704.1 307067738 9727128 complement(1062104..1062262) 1 NC_014494.1 Operon 503 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1062262 9727128 SPAP_1113 Streptococcus pneumoniae AP200 hypothetical protein YP_003876704.1 1062104 R 574093 CDS YP_003876705.1 307067739 9727129 complement(1062272..1063582) 1 NC_014494.1 Operon 503 Gene 2 COG0536 Predicted GTPase; putative GTPase 1063582 9727129 SPAP_1114 Streptococcus pneumoniae AP200 putative GTPase YP_003876705.1 1062272 R 574093 CDS YP_003876706.1 307067740 9727130 complement(1063646..1063780) 1 NC_014494.1 Operon 503 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1063780 9727130 SPAP_1115 Streptococcus pneumoniae AP200 hypothetical protein YP_003876706.1 1063646 R 574093 CDS YP_003876707.1 307067741 9727131 complement(1063839..1064015) 1 NC_014494.1 Operon 503 Gene 4 COG1983 Putative stress-responsive transcriptional regulator; putative stress-responsive transcriptional regulator 1064015 9727131 SPAP_1116 Streptococcus pneumoniae AP200 putative stress-responsive transcriptional regulator YP_003876707.1 1063839 R 574093 CDS YP_003876708.1 307067742 9727132 complement(1064046..1065371) 1 NC_014494.1 Operon 503 Gene 5 COG0438 Glycosyltransferase; glycosyltransferase 1065371 9727132 SPAP_1117 Streptococcus pneumoniae AP200 glycosyltransferase YP_003876708.1 1064046 R 574093 CDS YP_003876709.1 307067743 9727133 complement(1065387..1066430) 1 NC_014494.1 Operon 503 Gene 6 COG0438 Glycosyltransferase; glycosyltransferase 1066430 9727133 SPAP_1118 Streptococcus pneumoniae AP200 glycosyltransferase YP_003876709.1 1065387 R 574093 CDS YP_003876710.1 307067744 9727134 complement(1066545..1066874) 1 NC_014494.1 Operon 504 Gene 1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; putative metal-sulfur cluster biosynthetic enzyme 1066874 9727134 SPAP_1119 Streptococcus pneumoniae AP200 putative metal-sulfur cluster biosynthetic enzyme YP_003876710.1 1066545 R 574093 CDS YP_003876711.1 307067745 9727135 complement(1066888..1067997) 1 NC_014494.1 Operon 504 Gene 2 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) 1067997 9727135 SPAP_1120 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_003876711.1 1066888 R 574093 CDS YP_003876712.1 307067746 9727136 complement(1068000..1069760) 1 NC_014494.1 Operon 504 Gene 3 COG0358 DNA primase (bacterial type); DNA primase 1069760 9727136 SPAP_1121 Streptococcus pneumoniae AP200 DNA primase YP_003876712.1 1068000 R 574093 CDS YP_003876713.1 307067747 9727137 complement(1069869..1070501) 1 NC_014494.1 transposase-like protein, IS1239 1070501 9727137 SPAP_1122 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876713.1 1069869 R 574093 CDS YP_003876714.1 307067748 9727138 complement(1070651..1070821) 1 NC_014494.1 transposase-like protein, IS1239 1070821 9727138 SPAP_1123 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876714.1 1070651 R 574093 CDS YP_003876715.1 307067749 9727139 complement(1071093..1071851) 1 NC_014494.1 Operon 506 Gene 1 COG1101 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase 1071851 9727139 SPAP_1124 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876715.1 1071093 R 574093 CDS YP_003876716.1 307067750 9727140 complement(1071848..1072714) 1 NC_014494.1 Operon 506 Gene 2 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease 1072714 9727140 SPAP_1125 Streptococcus pneumoniae AP200 ABC transporter permease YP_003876716.1 1071848 R 574093 CDS YP_003876717.1 307067751 9727141 complement(1072783..1073787) 1 NC_014494.1 Operon 506 Gene 3 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic 1073787 9727141 SPAP_1126 Streptococcus pneumoniae AP200 ABC transporter periplasmic YP_003876717.1 1072783 R 574093 CDS YP_003876718.1 307067752 9727142 complement(1074200..1076896) 1 NC_014494.1 Operon 507 Gene 1 COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 1076896 9727142 SPAP_1127 Streptococcus pneumoniae AP200 phosphoenolpyruvate carboxylase YP_003876718.1 1074200 R 574093 CDS YP_003876719.1 307067753 9727143 complement(1076916..1078145) 1 NC_014494.1 Operon 507 Gene 2 COG0772 Bacterial cell division membrane protein; cell division membrane protein 1078145 9727143 SPAP_1128 Streptococcus pneumoniae AP200 cell division membrane protein YP_003876719.1 1076916 R 574093 CDS YP_003876720.1 307067754 9727144 complement(1078409..1078603) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1078603 9727144 SPAP_1129 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876720.1 1078409 R 574093 CDS YP_003876721.1 307067755 9727145 1078702..1078965 1 NC_014494.1 Operon 509 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1078965 9727145 SPAP_1130 Streptococcus pneumoniae AP200 hypothetical protein YP_003876721.1 1078702 D 574093 CDS YP_003876722.1 307067756 9727146 complement(1079052..1079273) 1 NC_014494.1 Operon 510 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1079273 9727146 SPAP_1131 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876722.1 1079052 R 574093 CDS YP_003876723.1 307067757 9727147 complement(1079953..1080705) 1 NC_014494.1 Operon 511 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 1080705 9727147 SPAP_1132 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003876723.1 1079953 R 574093 CDS YP_003876724.1 307067758 9727148 complement(1080757..1081164) 1 NC_014494.1 Operon 511 Gene 2 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 1081164 9727148 SPAP_1133 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003876724.1 1080757 R 574093 CDS YP_003876725.1 307067759 9727149 complement(1081166..1082110) 1 NC_014494.1 Operon 511 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1082110 9727149 SPAP_1134 Streptococcus pneumoniae AP200 hypothetical protein YP_003876725.1 1081166 R 574093 CDS YP_003876726.1 307067760 9727150 complement(1082251..1082616) 1 NC_014494.1 Operon 512 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 1082616 9727150 SPAP_1135 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876726.1 1082251 R 574093 CDS YP_003876727.1 307067761 9727151 complement(1082628..1083053) 1 NC_014494.1 transposase-like protein, IS1515 1083053 9727151 SPAP_1136 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003876727.1 1082628 R 574093 CDS YP_003876728.1 307067762 9727152 complement(1083079..1083282) 1 NC_014494.1 Operon 512 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1083282 9727152 SPAP_1137 Streptococcus pneumoniae AP200 hypothetical protein YP_003876728.1 1083079 R 574093 CDS YP_003876729.1 307067763 9727153 complement(1083306..1084334) 1 NC_014494.1 Operon 512 Gene 4 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1084334 9727153 SPAP_1138 Streptococcus pneumoniae AP200 UDP-glucose 4-epimerase YP_003876729.1 1083306 R 574093 CDS YP_003876730.1 307067764 9727154 complement(1084336..1085007) 1 NC_014494.1 Operon 512 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 1085007 9727154 SPAP_1139 Streptococcus pneumoniae AP200 hypothetical protein YP_003876730.1 1084336 R 574093 CDS YP_003876731.1 307067765 9727155 complement(1085010..1086104) 1 NC_014494.1 Operon 512 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 1086104 9727155 SPAP_1140 Streptococcus pneumoniae AP200 hypothetical protein YP_003876731.1 1085010 R 574093 CDS YP_003876732.1 307067766 9727156 complement(1086108..1086284) 1 NC_014494.1 Operon 512 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 1086284 9727156 SPAP_1141 Streptococcus pneumoniae AP200 hypothetical protein YP_003876732.1 1086108 R 574093 CDS YP_003876733.1 307067767 9727157 complement(1086636..1087358) 1 NC_014494.1 Operon 513 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1087358 9727157 SPAP_1142 Streptococcus pneumoniae AP200 hypothetical protein YP_003876733.1 1086636 R 574093 CDS YP_003876734.1 307067768 9727158 complement(1087345..1087764) 1 NC_014494.1 Operon 513 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1087764 9727158 SPAP_1143 Streptococcus pneumoniae AP200 hypothetical protein YP_003876734.1 1087345 R 574093 CDS YP_003876735.1 307067769 9727159 1088471..1089322 1 NC_014494.1 Operon 514 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1089322 9727159 SPAP_1144 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876735.1 1088471 D 574093 CDS YP_003876736.1 307067770 9727160 complement(1089363..1089950) 1 NC_014494.1 Operon 515 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1089950 9727160 SPAP_1145 Streptococcus pneumoniae AP200 hypothetical protein YP_003876736.1 1089363 R 574093 CDS YP_003876737.1 307067771 9727161 complement(1090089..1090289) 1 NC_014494.1 Operon 516 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1090289 9727161 SPAP_1146 Streptococcus pneumoniae AP200 hypothetical protein YP_003876737.1 1090089 R 574093 CDS YP_003876738.1 307067772 9727162 complement(1090325..1090519) 1 NC_014494.1 Operon 516 Gene 2 COG3843 Type IV secretory pathway, VirD2 components (relaxase); type IV secretory pathway, VirD2 components (relaxase) 1090519 9727162 SPAP_1147 Streptococcus pneumoniae AP200 type IV secretory pathway, VirD2 components (relaxase) YP_003876738.1 1090325 R 574093 CDS YP_003876739.1 307067773 9727163 complement(1090648..1091775) 1 NC_014494.1 Operon 517 Gene 1 COG0366 Glycosidases; glycosidase 1091775 9727163 SPAP_1148 Streptococcus pneumoniae AP200 glycosidase YP_003876739.1 1090648 R 574093 CDS YP_003876740.1 307067774 9727164 complement(1091938..1092822) 1 NC_014494.1 Operon 518 Gene 1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; sphingosine kinase 1092822 9727164 SPAP_1149 Streptococcus pneumoniae AP200 sphingosine kinase YP_003876740.1 1091938 R 574093 CDS YP_003876741.1 307067775 9727165 complement(1092934..1093788) 1 NC_014494.1 Operon 519 Gene 1 COG1397 ADP-ribosylglycohydrolase; ADP-ribosylglycohydrolase 1093788 9727165 SPAP_1150 Streptococcus pneumoniae AP200 ADP-ribosylglycohydrolase YP_003876741.1 1092934 R 574093 CDS YP_003876742.1 307067776 9727166 complement(1093846..1094604) 1 NC_014494.1 Operon 519 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1094604 9727166 SPAP_1151 Streptococcus pneumoniae AP200 hypothetical protein YP_003876742.1 1093846 R 574093 CDS YP_003876743.1 307067777 9727167 complement(1094666..1094860) 1 NC_014494.1 Operon 519 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1094860 9727167 SPAP_1152 Streptococcus pneumoniae AP200 hypothetical protein YP_003876743.1 1094666 R 574093 CDS YP_003876744.1 307067778 9727168 1095042..1095203 1 NC_014494.1 Operon 520 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1095203 9727168 SPAP_1153 Streptococcus pneumoniae AP200 hypothetical protein YP_003876744.1 1095042 D 574093 CDS YP_003876745.1 307067779 9727169 complement(1095175..1095741) 1 NC_014494.1 Operon 521 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1095741 9727169 SPAP_1154 Streptococcus pneumoniae AP200 hypothetical protein YP_003876745.1 1095175 R 574093 CDS YP_003876746.1 307067780 9727170 complement(1096009..1097688) 1 NC_014494.1 Operon 522 Gene 1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase 1097688 9727170 SPAP_1155 Streptococcus pneumoniae AP200 site-specific recombinase YP_003876746.1 1096009 R 574093 CDS YP_003876747.1 307067781 9727171 complement(1097779..1097940) 1 NC_014494.1 Operon 522 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1097940 9727171 SPAP_1156 Streptococcus pneumoniae AP200 hypothetical protein YP_003876747.1 1097779 R 574093 CDS YP_003876748.1 307067782 9727172 complement(1098624..1099352) 1 NC_014494.1 Operon 523 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1099352 9727172 SPAP_1157 Streptococcus pneumoniae AP200 hypothetical protein YP_003876748.1 1098624 R 574093 CDS YP_003876749.1 307067783 9727173 complement(1099479..1100006) 1 NC_014494.1 Operon 523 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1100006 9727173 SPAP_1158 Streptococcus pneumoniae AP200 hypothetical protein YP_003876749.1 1099479 R 574093 CDS YP_003876750.1 307067784 9727174 complement(1100192..1100365) 1 NC_014494.1 Operon 524 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1100365 9727174 SPAP_1159 Streptococcus pneumoniae AP200 hypothetical protein YP_003876750.1 1100192 R 574093 CDS YP_003876751.1 307067785 9727175 complement(1100439..1102079) 1 NC_014494.1 Operon 524 Gene 2 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha 1102079 9727175 SPAP_1160 Streptococcus pneumoniae AP200 ATP-dependent exoDNAse (exonuclease V) subunit alpha YP_003876751.1 1100439 R 574093 CDS YP_003876752.1 307067786 9727176 complement(1102389..1102703) 1 NC_014494.1 Operon 525 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1102703 9727176 SPAP_1161 Streptococcus pneumoniae AP200 hypothetical protein YP_003876752.1 1102389 R 574093 CDS YP_003876753.1 307067787 9727177 complement(1102762..1103007) 1 NC_014494.1 Operon 525 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1103007 9727177 SPAP_1162 Streptococcus pneumoniae AP200 hypothetical protein YP_003876753.1 1102762 R 574093 CDS YP_003876754.1 307067788 9727178 1102953..1103066 1 NC_014494.1 Operon 526 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1103066 9727178 SPAP_1163 Streptococcus pneumoniae AP200 hypothetical protein YP_003876754.1 1102953 D 574093 CDS YP_003876755.1 307067789 9727179 complement(1103575..1104369) 1 NC_014494.1 Operon 527 Gene 1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; cobalamin/Fe3+-siderophores ABC transporter ATPase 1104369 9727179 SPAP_1164 Streptococcus pneumoniae AP200 cobalamin/Fe3+-siderophores ABC transporter ATPase YP_003876755.1 1103575 R 574093 CDS YP_003876756.1 307067790 9727180 complement(1104369..1105376) 1 NC_014494.1 Operon 527 Gene 2 COG0609 ABC-type Fe3+-siderophore transport system, permease component; Fe3+-siderophore ABC transporter permease 1105376 9727180 SPAP_1165 Streptococcus pneumoniae AP200 Fe3+-siderophore ABC transporter permease YP_003876756.1 1104369 R 574093 CDS YP_003876757.1 307067791 9727181 complement(1105376..1105720) 1 NC_014494.1 Operon 527 Gene 3 COG0609 ABC-type Fe3+-siderophore transport system, permease component; Fe3+-siderophore ABC transporter permease 1105720 9727181 SPAP_1166 Streptococcus pneumoniae AP200 Fe3+-siderophore ABC transporter permease YP_003876757.1 1105376 R 574093 CDS YP_003876758.1 307067792 9727182 complement(1106373..1107398) 1 NC_014494.1 Operon 527 Gene 4 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; Fe3+-hydroxamate ABC transporter periplasmic protein 1107398 9727182 SPAP_1167 Streptococcus pneumoniae AP200 Fe3+-hydroxamate ABC transporter periplasmic protein YP_003876758.1 1106373 R 574093 CDS YP_003876759.1 307067793 9727183 complement(1107519..1107788) 1 NC_014494.1 Operon 528 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1107788 9727183 SPAP_1168 Streptococcus pneumoniae AP200 hypothetical protein YP_003876759.1 1107519 R 574093 CDS YP_003876760.1 307067794 9727184 complement(1107792..1108010) 1 NC_014494.1 Operon 528 Gene 2 COG3655 Predicted transcriptional regulator; putative transcriptional regulator 1108010 9727184 SPAP_1169 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003876760.1 1107792 R 574093 CDS YP_003876761.1 307067795 9727185 complement(1108748..1110379) 1 NC_014494.1 Operon 529 Gene 1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; SAM-dependent methyltransferase 1110379 9727185 SPAP_1170 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003876761.1 1108748 R 574093 CDS YP_003876762.1 307067796 9727186 complement(1110453..1111427) 1 NC_014494.1 Operon 530 Gene 1 COG4086 Predicted secreted protein; hypothetical protein 1111427 9727186 SPAP_1171 Streptococcus pneumoniae AP200 hypothetical protein YP_003876762.1 1110453 R 574093 CDS YP_003876763.1 307067797 9727187 complement(1111501..1112115) 1 NC_014494.1 Operon 530 Gene 2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase-like regulatory protein 1112115 9727187 SPAP_1172 Streptococcus pneumoniae AP200 soluble lytic murein transglycosylase-like regulatory protein YP_003876763.1 1111501 R 574093 CDS YP_003876764.1 307067798 9727188 complement(1112115..1113089) 1 NC_014494.1 Operon 530 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1113089 9727188 SPAP_1173 Streptococcus pneumoniae AP200 hypothetical protein YP_003876764.1 1112115 R 574093 CDS YP_003876765.1 307067799 9727189 complement(1113097..1114353) 1 NC_014494.1 Operon 530 Gene 4 COG0112 Glycine/serine hydroxymethyltransferase; glycine/serine hydroxymethyltransferase 1114353 9727189 SPAP_1174 Streptococcus pneumoniae AP200 glycine/serine hydroxymethyltransferase YP_003876765.1 1113097 R 574093 CDS YP_003876766.1 307067800 9727190 complement(1114415..1114846) 1 NC_014494.1 Operon 530 Gene 5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1114846 9727190 SPAP_1175 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003876766.1 1114415 R 574093 CDS YP_003876767.1 307067801 9727191 complement(1114848..1115450) 1 NC_014494.1 Operon 530 Gene 6 COG0009 Putative translation factor (SUA5); putative translation factor 1115450 9727191 SPAP_1176 Streptococcus pneumoniae AP200 putative translation factor YP_003876767.1 1114848 R 574093 CDS YP_003876768.1 307067802 9727192 complement(1115434..1116273) 1 NC_014494.1 Operon 530 Gene 7 COG2890 Methylase of polypeptide chain release factors; methylase of polypeptide chain release factors 1116273 9727192 SPAP_1177 Streptococcus pneumoniae AP200 methylase of polypeptide chain release factors YP_003876768.1 1115434 R 574093 CDS YP_003876769.1 307067803 9727193 complement(1116273..1117352) 1 NC_014494.1 Operon 530 Gene 8 COG0216 Protein chain release factor A; protein chain release factor A 1117352 9727193 SPAP_1178 Streptococcus pneumoniae AP200 protein chain release factor A YP_003876769.1 1116273 R 574093 CDS YP_003876770.1 307067804 9727194 complement(1117362..1117841) 1 NC_014494.1 Operon 530 Gene 9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1117841 9727194 SPAP_1179 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003876770.1 1117362 R 574093 CDS YP_003876771.1 307067805 9727195 complement(1117831..1118430) 1 NC_014494.1 Operon 530 Gene 10 COG1435 Thymidine kinase; thymidine kinase 1118430 9727195 SPAP_1180 Streptococcus pneumoniae AP200 thymidine kinase YP_003876771.1 1117831 R 574093 CDS YP_003876772.1 307067806 9727196 1118553..1118735 1 NC_014494.1 Operon 531 Gene 1 COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; hypothetical protein 1118735 9727196 SPAP_1181 Streptococcus pneumoniae AP200 hypothetical protein YP_003876772.1 1118553 D 574093 CDS YP_003876773.1 307067807 9727197 1118872..1120245 1 NC_014494.1 Operon 532 Gene 1 COG0486 Predicted GTPase; putative GTPase 1120245 9727197 SPAP_1182 Streptococcus pneumoniae AP200 putative GTPase YP_003876773.1 1118872 D 574093 CDS YP_003876774.1 307067808 9727198 complement(1120292..1121227) 1 NC_014494.1 Operon 533 Gene 1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase 1121227 9727198 SPAP_1183 Streptococcus pneumoniae AP200 dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_003876774.1 1120292 R 574093 CDS YP_003876775.1 307067809 9727199 complement(1121283..1122359) 1 NC_014494.1 Operon 533 Gene 2 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 1122359 9727199 SPAP_1184 Streptococcus pneumoniae AP200 aspartate-semialdehyde dehydrogenase YP_003876775.1 1121283 R 574093 CDS YP_003876776.1 307067810 9727201 complement(1123117..1123626) 1 NC_014494.1 Operon 534 Gene 1 COG4708 Predicted membrane protein; hypothetical protein 1123626 9727201 SPAP_1186 Streptococcus pneumoniae AP200 hypothetical protein YP_003876776.1 1123117 R 574093 CDS YP_003876777.1 307067811 9727202 1123749..1124180 1 NC_014494.1 Operon 535 Gene 1 COG2246 Predicted membrane protein; hypothetical protein 1124180 9727202 SPAP_1187 Streptococcus pneumoniae AP200 hypothetical protein YP_003876777.1 1123749 D 574093 CDS YP_003876778.1 307067812 9727203 1124262..1124639 1 NC_014494.1 Operon 535 Gene 2 COG1970 Large-conductance mechanosensitive channel; large-conductance mechanosensitive channel 1124639 9727203 SPAP_1188 Streptococcus pneumoniae AP200 large-conductance mechanosensitive channel YP_003876778.1 1124262 D 574093 CDS YP_003876779.1 307067813 9727204 complement(1124681..1125775) 1 NC_014494.1 Operon 536 Gene 1 COG0276 Protoheme ferro-lyase (ferrochelatase); protoheme ferro-lyase 1125775 9727204 SPAP_1189 Streptococcus pneumoniae AP200 protoheme ferro-lyase YP_003876779.1 1124681 R 574093 CDS YP_003876780.1 307067814 9727205 complement(1125853..1126032) 1 NC_014494.1 Operon 536 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1126032 9727205 SPAP_1190 Streptococcus pneumoniae AP200 hypothetical protein YP_003876780.1 1125853 R 574093 CDS YP_003876781.1 307067815 9727206 complement(1126077..1126685) 1 NC_014494.1 Operon 536 Gene 3 COG4509 Uncharacterized protein conserved in bacteria; sortase SrtG2 1126685 srtG2 9727206 srtG2 Streptococcus pneumoniae AP200 sortase SrtG2 YP_003876781.1 1126077 R 574093 CDS YP_003876782.1 307067816 9727207 complement(1126763..1127761) 1 NC_014494.1 Operon 537 Gene 1 COG4509 Uncharacterized protein conserved in bacteria; sortase SrtG1 1127761 srtG1 9727207 srtG1 Streptococcus pneumoniae AP200 sortase SrtG1 YP_003876782.1 1126763 R 574093 CDS YP_003876783.1 307067817 9727208 complement(1127779..1128975) 1 NC_014494.1 LPXTG containing cell wall anchored protein; pilus backbone; PitB 1128975 pitB 9727208 pitB Streptococcus pneumoniae AP200 PitB YP_003876783.1 1127779 R 574093 CDS YP_003876784.1 307067818 9727209 complement(1129020..1129571) 1 NC_014494.1 Operon 537 Gene 3 COG0681 Signal peptidase I; signal peptidase-like protein sipA 1129571 sipA 9727209 sipA Streptococcus pneumoniae AP200 signal peptidase-like protein sipA YP_003876784.1 1129020 R 574093 CDS YP_003876785.1 307067819 9727210 complement(1129571..1131397) 1 NC_014494.1 Operon 537 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1131397 9727210 SPAP_1195 Streptococcus pneumoniae AP200 hypothetical protein YP_003876785.1 1129571 R 574093 CDS YP_003876786.1 307067820 9727211 complement(1131653..1132156) 1 NC_014494.1 Operon 538 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1132156 9727211 SPAP_1196 Streptococcus pneumoniae AP200 hypothetical protein YP_003876786.1 1131653 R 574093 CDS YP_003876787.1 307067821 9727212 1132515..1133738 1 NC_014494.1 Operon 539 Gene 1 COG2195 Di- and tripeptidases; di- and tripeptidase 1133738 9727212 SPAP_1197 Streptococcus pneumoniae AP200 di- and tripeptidase YP_003876787.1 1132515 D 574093 CDS YP_003876788.1 307067822 9727213 complement(1133774..1134403) 1 NC_014494.1 Operon 540 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1134403 9727213 SPAP_1198 Streptococcus pneumoniae AP200 hypothetical protein YP_003876788.1 1133774 R 574093 CDS YP_003876789.1 307067823 9727214 complement(1134698..1134937) 1 NC_014494.1 Operon 541 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1134937 9727214 SPAP_1199 Streptococcus pneumoniae AP200 hypothetical protein YP_003876789.1 1134698 R 574093 CDS YP_003876790.1 307067824 9727215 complement(1134927..1135235) 1 NC_014494.1 Operon 541 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1135235 9727215 SPAP_1200 Streptococcus pneumoniae AP200 hypothetical protein YP_003876790.1 1134927 R 574093 CDS YP_003876791.1 307067825 9727216 complement(1136099..1139218) 1 NC_014494.1 Operon 542 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1139218 9727216 SPAP_1201 Streptococcus pneumoniae AP200 hypothetical protein YP_003876791.1 1136099 R 574093 CDS YP_003876792.1 307067826 9727217 complement(1139428..1140462) 1 NC_014494.1 Operon 543 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1140462 9727217 SPAP_1202 Streptococcus pneumoniae AP200 hypothetical protein YP_003876792.1 1139428 R 574093 CDS YP_003876793.1 307067827 9727218 complement(1140521..1141255) 1 NC_014494.1 Operon 543 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1141255 9727218 SPAP_1203 Streptococcus pneumoniae AP200 hypothetical protein YP_003876793.1 1140521 R 574093 CDS YP_003876794.1 307067828 9727219 complement(1141277..1141945) 1 NC_014494.1 Operon 543 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1141945 9727219 SPAP_1204 Streptococcus pneumoniae AP200 hypothetical protein YP_003876794.1 1141277 R 574093 CDS YP_003876795.1 307067829 9727220 complement(1142103..1144553) 1 NC_014494.1 Operon 544 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1144553 9727220 SPAP_1205 Streptococcus pneumoniae AP200 hypothetical protein YP_003876795.1 1142103 R 574093 CDS YP_003876796.1 307067830 9727221 complement(1144806..1146530) 1 NC_014494.1 Operon 545 Gene 1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); PTS system phosphoenolpyruvate-protein kinase 1146530 9727221 SPAP_1206 Streptococcus pneumoniae AP200 PTS system phosphoenolpyruvate-protein kinase YP_003876796.1 1144806 R 574093 CDS YP_003876797.1 307067831 9727222 complement(1146545..1146808) 1 NC_014494.1 Operon 545 Gene 2 COG1925 Phosphotransferase system, HPr-related proteins; PTS system HPr-related protein 1146808 9727222 SPAP_1207 Streptococcus pneumoniae AP200 PTS system HPr-related protein YP_003876797.1 1146545 R 574093 CDS YP_003876798.1 307067832 9727223 1147159..1147377 1 NC_014494.1 Operon 546 Gene 1 COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein 1147377 9727223 SPAP_1208 Streptococcus pneumoniae AP200 glutaredoxin-like protein YP_003876798.1 1147159 D 574093 CDS YP_003876799.1 307067833 9727224 1147458..1149617 1 NC_014494.1 Operon 546 Gene 2 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide reductase subunit alpha 1149617 9727224 SPAP_1209 Streptococcus pneumoniae AP200 ribonucleotide reductase subunit alpha YP_003876799.1 1147458 D 574093 CDS YP_003876800.1 307067834 9727225 1149805..1150767 1 NC_014494.1 Operon 546 Gene 3 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide reductase subunit beta 1150767 9727225 SPAP_1210 Streptococcus pneumoniae AP200 ribonucleotide reductase subunit beta YP_003876800.1 1149805 D 574093 CDS YP_003876801.1 307067835 9727226 1150949..1151710 1 NC_014494.1 Operon 547 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 1151710 9727226 SPAP_1211 Streptococcus pneumoniae AP200 sugar metabolism transcriptional regulator YP_003876801.1 1150949 D 574093 CDS YP_003876802.1 307067836 9727227 complement(1151995..1152246) 1 NC_014494.1 Operon 548 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1152246 9727227 SPAP_1212 Streptococcus pneumoniae AP200 hypothetical protein YP_003876802.1 1151995 R 574093 CDS YP_003876803.1 307067837 9727228 complement(1152289..1153695) 1 NC_014494.1 Operon 548 Gene 2 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 1153695 9727228 SPAP_1213 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003876803.1 1152289 R 574093 CDS YP_003876804.1 307067838 9727229 complement(1153910..1155604) 1 NC_014494.1 Operon 548 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1155604 9727229 SPAP_1214 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003876804.1 1153910 R 574093 CDS YP_003876805.1 307067839 9727230 complement(1155606..1155923) 1 NC_014494.1 Operon 548 Gene 4 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 1155923 9727230 SPAP_1215 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIA YP_003876805.1 1155606 R 574093 CDS YP_003876806.1 307067840 9727231 complement(1155959..1156795) 1 NC_014494.1 Operon 548 Gene 5 COG3711 Transcriptional antiterminator; transcriptional antiterminator 1156795 9727231 SPAP_1216 Streptococcus pneumoniae AP200 transcriptional antiterminator YP_003876806.1 1155959 R 574093 CDS YP_003876807.1 307067841 9727232 complement(1157029..1158009) 1 NC_014494.1 Operon 549 Gene 1 COG3684 Tagatose-1,6-bisphosphate aldolase; tagatose-1,6-bisphosphate aldolase 1158009 9727232 SPAP_1217 Streptococcus pneumoniae AP200 tagatose-1,6-bisphosphate aldolase YP_003876807.1 1157029 R 574093 CDS YP_003876808.1 307067842 9727233 complement(1158011..1158940) 1 NC_014494.1 Operon 549 Gene 2 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB 1158940 9727233 SPAP_1218 Streptococcus pneumoniae AP200 fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB YP_003876808.1 1158011 R 574093 CDS YP_003876809.1 307067843 9727234 complement(1158951..1159466) 1 NC_014494.1 Operon 549 Gene 3 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB 1159466 9727234 SPAP_1219 Streptococcus pneumoniae AP200 ribose 5-phosphate isomerase RpiB YP_003876809.1 1158951 R 574093 CDS YP_003876810.1 307067844 9727235 complement(1159497..1159922) 1 NC_014494.1 Operon 549 Gene 4 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB 1159922 9727235 SPAP_1220 Streptococcus pneumoniae AP200 ribose 5-phosphate isomerase RpiB YP_003876810.1 1159497 R 574093 CDS YP_003876811.1 307067845 9727236 complement(1160079..1160555) 1 NC_014494.1 Operon 550 Gene 1 COG2017 Galactose mutarotase and related enzymes; galactose mutarotase-like enzyme 1160555 9727236 SPAP_1221 Streptococcus pneumoniae AP200 galactose mutarotase-like enzyme YP_003876811.1 1160079 R 574093 CDS YP_003876812.1 307067846 9727237 complement(1160592..1161056) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1161056 9727237 SPAP_1222 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876812.1 1160592 R 574093 CDS YP_003876813.1 307067847 9727238 complement(1161215..1161397) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1161397 9727238 SPAP_1223 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876813.1 1161215 R 574093 CDS YP_003876814.1 307067848 9727239 complement(1161752..1162228) 1 NC_014494.1 Operon 552 Gene 1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein 1162228 9727239 SPAP_1224 Streptococcus pneumoniae AP200 PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein YP_003876814.1 1161752 R 574093 CDS YP_003876815.1 307067849 9727240 1162408..1162695 1 NC_014494.1 Operon 553 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1162695 9727240 SPAP_1225 Streptococcus pneumoniae AP200 hypothetical protein YP_003876815.1 1162408 D 574093 CDS YP_003876816.1 307067850 9727241 complement(1162776..1164599) 1 NC_014494.1 Operon 554 Gene 1 COG0481 Membrane GTPase LepA; membrane GTPase LepA 1164599 9727241 SPAP_1226 Streptococcus pneumoniae AP200 membrane GTPase LepA YP_003876816.1 1162776 R 574093 CDS YP_003876817.1 307067851 9727242 complement(1164678..1165406) 1 NC_014494.1 Operon 554 Gene 2 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase 1165406 9727242 SPAP_1227 Streptococcus pneumoniae AP200 diadenosine tetraphosphatase-like serine/threonine protein phosphatase YP_003876817.1 1164678 R 574093 CDS YP_003876818.1 307067852 9727243 complement(1165408..1167075) 1 NC_014494.1 Operon 554 Gene 3 COG0497 ATPase involved in DNA repair; DNA repair ATPase 1167075 9727243 SPAP_1228 Streptococcus pneumoniae AP200 DNA repair ATPase YP_003876818.1 1165408 R 574093 CDS YP_003876819.1 307067853 9727244 complement(1167082..1167513) 1 NC_014494.1 Operon 554 Gene 4 COG1438 Arginine repressor; arginine repressor 1167513 9727244 SPAP_1229 Streptococcus pneumoniae AP200 arginine repressor YP_003876819.1 1167082 R 574093 CDS YP_003876820.1 307067854 9727245 complement(1167506..1168321) 1 NC_014494.1 Operon 554 Gene 5 COG1189 Predicted rRNA methylase; putative rRNA methylase 1168321 9727245 SPAP_1230 Streptococcus pneumoniae AP200 putative rRNA methylase YP_003876820.1 1167506 R 574093 CDS YP_003876821.1 307067855 9727246 complement(1168314..1169189) 1 NC_014494.1 Operon 554 Gene 6 COG0142 Geranylgeranyl pyrophosphate synthase; geranylgeranyl pyrophosphate synthase 1169189 9727246 SPAP_1231 Streptococcus pneumoniae AP200 geranylgeranyl pyrophosphate synthase YP_003876821.1 1168314 R 574093 CDS YP_003876822.1 307067856 9727247 complement(1169186..1169398) 1 NC_014494.1 Operon 554 Gene 7 COG1722 Exonuclease VII small subunit; exonuclease VII small subunit 1169398 9727247 SPAP_1232 Streptococcus pneumoniae AP200 exonuclease VII small subunit YP_003876822.1 1169186 R 574093 CDS YP_003876823.1 307067857 9727248 complement(1169376..1170716) 1 NC_014494.1 Operon 554 Gene 8 COG1570 Exonuclease VII, large subunit; exonuclease VII large subunit 1170716 9727248 SPAP_1233 Streptococcus pneumoniae AP200 exonuclease VII large subunit YP_003876823.1 1169376 R 574093 CDS YP_003876824.1 307067858 9727249 complement(1170844..1171482) 1 NC_014494.1 Operon 555 Gene 1 COG0572 Uridine kinase; Uridine kinase 1171482 9727249 SPAP_1234 Streptococcus pneumoniae AP200 Uridine kinase YP_003876824.1 1170844 R 574093 CDS YP_003876825.1 307067859 9727250 complement(1171590..1171889) 1 NC_014494.1 Operon 556 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1171889 9727250 SPAP_1235 Streptococcus pneumoniae AP200 hypothetical protein YP_003876825.1 1171590 R 574093 CDS YP_003876826.1 307067860 9727251 complement(1171889..1171984) 1 NC_014494.1 Operon 556 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1171984 9727251 SPAP_1236 Streptococcus pneumoniae AP200 hypothetical protein YP_003876826.1 1171889 R 574093 CDS YP_003876827.1 307067861 9727252 complement(1172133..1173011) 1 NC_014494.1 Operon 557 Gene 1 COG0130 Pseudouridine synthase; pseudouridine synthase 1173011 9727252 SPAP_1237 Streptococcus pneumoniae AP200 pseudouridine synthase YP_003876827.1 1172133 R 574093 CDS YP_003876828.1 307067862 9727253 complement(1173112..1176042) 1 NC_014494.1 Operon 558 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1176042 9727253 SPAP_1238 Streptococcus pneumoniae AP200 hypothetical protein YP_003876828.1 1173112 R 574093 CDS YP_003876829.1 307067863 9727254 complement(1176030..1176227) 1 NC_014494.1 Operon 558 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1176227 9727254 SPAP_1239 Streptococcus pneumoniae AP200 hypothetical protein YP_003876829.1 1176030 R 574093 CDS YP_003876830.1 307067864 9727255 complement(1176239..1177513) 1 NC_014494.1 Operon 558 Gene 3 COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein 1177513 9727255 SPAP_1240 Streptococcus pneumoniae AP200 hypothetical protein YP_003876830.1 1176239 R 574093 CDS YP_003876831.1 307067865 9727256 complement(1177609..1178724) 1 NC_014494.1 Operon 559 Gene 1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase 1178724 9727256 SPAP_1241 Streptococcus pneumoniae AP200 O-acetylhomoserine sulfhydrylase YP_003876831.1 1177609 R 574093 CDS YP_003876832.1 307067866 9727257 complement(1178746..1178868) 1 NC_014494.1 Operon 559 Gene 2 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase 1178868 9727257 SPAP_1242 Streptococcus pneumoniae AP200 O-acetylhomoserine sulfhydrylase YP_003876832.1 1178746 R 574093 CDS YP_003876833.1 307067867 9727258 complement(1179016..1179813) 1 NC_014494.1 Operon 560 Gene 1 COG2116 Formate/nitrite family of transporters; formate/nitrite family transporter 1179813 9727258 SPAP_1243 Streptococcus pneumoniae AP200 formate/nitrite family transporter YP_003876833.1 1179016 R 574093 CDS YP_003876834.1 307067868 9727259 complement(1180058..1180801) 1 NC_014494.1 Operon 561 Gene 1 COG3764 Sortase (surface protein transpeptidase); sortase 1180801 9727259 SPAP_1244 Streptococcus pneumoniae AP200 sortase YP_003876834.1 1180058 R 574093 CDS YP_003876835.1 307067869 9727260 complement(1180801..1183269) 1 NC_014494.1 Operon 561 Gene 2 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; type IIA topoisomerase subunit A 1183269 9727260 SPAP_1245 Streptococcus pneumoniae AP200 type IIA topoisomerase subunit A YP_003876835.1 1180801 R 574093 CDS YP_003876836.1 307067870 9727261 1183463..1184449 1 NC_014494.1 Operon 562 Gene 1 COG0039 Malate/lactate dehydrogenases; malate/lactate dehydrogenase 1184449 9727261 SPAP_1246 Streptococcus pneumoniae AP200 malate/lactate dehydrogenase YP_003876836.1 1183463 D 574093 CDS YP_003876837.1 307067871 9727262 complement(1184798..1185493) 1 NC_014494.1 Operon 563 Gene 1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; K+ transport systems NAD-binding component 1185493 9727262 SPAP_1247 Streptococcus pneumoniae AP200 K+ transport systems NAD-binding component YP_003876837.1 1184798 R 574093 CDS YP_003876838.1 307067872 9727263 complement(1185540..1185803) 1 NC_014494.1 Operon 563 Gene 2 COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; cytotoxic translational repressor of toxin-antitoxin stability system 1185803 9727263 SPAP_1248 Streptococcus pneumoniae AP200 cytotoxic translational repressor of toxin-antitoxin stability system YP_003876838.1 1185540 R 574093 CDS YP_003876839.1 307067873 9727264 complement(1185796..1186038) 1 NC_014494.1 Operon 563 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1186038 9727264 SPAP_1249 Streptococcus pneumoniae AP200 hypothetical protein YP_003876839.1 1185796 R 574093 CDS YP_003876840.1 307067874 9727265 complement(1186129..1186938) 1 NC_014494.1 Operon 564 Gene 1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; metal-dependent hydrolases of the beta-lactamase superfamily I 1186938 9727265 SPAP_1250 Streptococcus pneumoniae AP200 metal-dependent hydrolases of the beta-lactamase superfamily I YP_003876840.1 1186129 R 574093 CDS YP_003876841.1 307067875 9727266 complement(1186940..1188289) 1 NC_014494.1 Operon 564 Gene 2 COG5002 Signal transduction histidine kinase; signal transduction histidine kinase 1188289 9727266 SPAP_1251 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003876841.1 1186940 R 574093 CDS YP_003876842.1 307067876 9727267 complement(1188282..1188986) 1 NC_014494.1 Operon 564 Gene 3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1188986 9727267 SPAP_1252 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003876842.1 1188282 R 574093 CDS YP_003876843.1 307067877 9727268 complement(1189041..1190216) 1 NC_014494.1 Operon 564 Gene 4 COG1194 A/G-specific DNA glycosylase; A/G-specific DNA glycosylase 1190216 9727268 SPAP_1253 Streptococcus pneumoniae AP200 A/G-specific DNA glycosylase YP_003876843.1 1189041 R 574093 CDS YP_003876844.1 307067878 9727269 complement(1190544..1192214) 1 NC_014494.1 Operon 565 Gene 1 COG2759 Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase 1192214 9727269 SPAP_1254 Streptococcus pneumoniae AP200 formyltetrahydrofolate synthetase YP_003876844.1 1190544 R 574093 CDS YP_003876845.1 307067879 9727270 1192444..1193133 1 NC_014494.1 Operon 566 Gene 1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; phosphopantothenoylcysteine synthetase/decarboxylase 1193133 9727270 SPAP_1255 Streptococcus pneumoniae AP200 phosphopantothenoylcysteine synthetase/decarboxylase YP_003876845.1 1192444 D 574093 CDS YP_003876846.1 307067880 9727271 1193145..1193696 1 NC_014494.1 Operon 566 Gene 2 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; phosphopantothenoylcysteine synthetase/decarboxylase 1193696 9727271 SPAP_1256 Streptococcus pneumoniae AP200 phosphopantothenoylcysteine synthetase/decarboxylase YP_003876846.1 1193145 D 574093 CDS YP_003876847.1 307067881 9727272 1193680..1194243 1 NC_014494.1 Operon 566 Gene 3 COG4684 Predicted membrane protein; hypothetical protein 1194243 9727272 SPAP_1257 Streptococcus pneumoniae AP200 hypothetical protein YP_003876847.1 1193680 D 574093 CDS YP_003876848.1 307067882 9727273 1194552..1195052 1 NC_014494.1 Operon 567 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1195052 9727273 SPAP_1258 Streptococcus pneumoniae AP200 hypothetical protein YP_003876848.1 1194552 D 574093 CDS YP_003876849.1 307067883 9727274 1195064..1195579 1 NC_014494.1 Operon 567 Gene 2 COG1827 Predicted small molecule binding protein (contains 3H domain); putative small molecule binding protein 1195579 9727274 SPAP_1259 Streptococcus pneumoniae AP200 putative small molecule binding protein YP_003876849.1 1195064 D 574093 CDS YP_003876850.1 307067884 9727275 complement(1195576..1196043) 1 NC_014494.1 Operon 568 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 1196043 9727275 SPAP_1260 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003876850.1 1195576 R 574093 CDS YP_003876851.1 307067885 9727276 complement(1196116..1196604) 1 NC_014494.1 Operon 568 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1196604 9727276 SPAP_1261 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003876851.1 1196116 R 574093 CDS YP_003876852.1 307067886 9727277 complement(1196570..1197133) 1 NC_014494.1 Operon 568 Gene 3 protein supported gi|116629704|ref|YP_814876.1| acetyltransferase; hypothetical protein 1197133 9727277 SPAP_1262 Streptococcus pneumoniae AP200 hypothetical protein YP_003876852.1 1196570 R 574093 CDS YP_003876853.1 307067887 9727278 complement(1197143..1199131) 1 NC_014494.1 Operon 568 Gene 4 COG0556 Helicase subunit of the DNA excision repair complex; DNA excision repair complex helicase 1199131 9727278 SPAP_1263 Streptococcus pneumoniae AP200 DNA excision repair complex helicase YP_003876853.1 1197143 R 574093 CDS YP_003876854.1 307067888 9727279 complement(1199208..1200161) 1 NC_014494.1 Operon 568 Gene 5 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 1200161 9727279 SPAP_1264 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876854.1 1199208 R 574093 CDS YP_003876855.1 307067889 9727280 1200331..1202496 1 NC_014494.1 Operon 569 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 1202496 9727280 SPAP_1265 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003876855.1 1200331 D 574093 CDS YP_003876856.1 307067890 9727281 1202496..1203236 1 NC_014494.1 Operon 569 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 1203236 9727281 SPAP_1266 Streptococcus pneumoniae AP200 hypothetical protein YP_003876856.1 1202496 D 574093 CDS YP_003876857.1 307067891 9727282 1203385..1204872 1 NC_014494.1 Operon 570 Gene 1 COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 1204872 9727282 SPAP_1267 Streptococcus pneumoniae AP200 glucose-6-phosphate 1-dehydrogenase YP_003876857.1 1203385 D 574093 CDS YP_003876858.1 307067892 9727283 complement(1204918..1206195) 1 NC_014494.1 Operon 571 Gene 1 protein supported gi|163762490|ref|ZP_02169555.1| ribosomal protein L28; hypothetical protein 1206195 9727283 SPAP_1268 Streptococcus pneumoniae AP200 hypothetical protein YP_003876858.1 1204918 R 574093 CDS YP_003876859.1 307067893 9727284 complement(1206199..1207017) 1 NC_014494.1 Operon 571 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1207017 9727284 SPAP_1269 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003876859.1 1206199 R 574093 CDS YP_003876860.1 307067894 9727285 complement(1207017..1207811) 1 NC_014494.1 Operon 571 Gene 3 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1207811 9727285 SPAP_1270 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003876860.1 1207017 R 574093 CDS YP_003876861.1 307067895 9727286 complement(1207808..1211347) 1 NC_014494.1 Operon 571 Gene 4 COG1196 Chromosome segregation ATPases; chromosome segregation ATPase 1211347 9727286 SPAP_1271 Streptococcus pneumoniae AP200 chromosome segregation ATPase YP_003876861.1 1207808 R 574093 CDS YP_003876862.1 307067896 9727287 complement(1211338..1212036) 1 NC_014494.1 Operon 571 Gene 5 COG0571 dsRNA-specific ribonuclease; dsRNA-specific ribonuclease 1212036 9727287 SPAP_1272 Streptococcus pneumoniae AP200 dsRNA-specific ribonuclease YP_003876862.1 1211338 R 574093 CDS YP_003876863.1 307067897 9727289 complement(1212354..1213340) 1 NC_014494.1 Operon 572 Gene 1 COG0516 IMP dehydrogenase/GMP reductase; IMP dehydrogenase/GMP reductase 1213340 9727289 SPAP_1274 Streptococcus pneumoniae AP200 IMP dehydrogenase/GMP reductase YP_003876863.1 1212354 R 574093 CDS YP_003876864.1 307067898 9727290 complement(1213515..1214834) 1 NC_014494.1 Operon 573 Gene 1 COG4268 McrBC 5-methylcytosine restriction system component; McrBC 5-methylcytosine restriction system component 1214834 9727290 SPAP_1275 Streptococcus pneumoniae AP200 McrBC 5-methylcytosine restriction system component YP_003876864.1 1213515 R 574093 CDS YP_003876865.1 307067899 9727291 complement(1214818..1216749) 1 NC_014494.1 Operon 573 Gene 2 COG1401 GTPase subunit of restriction endonuclease; restriction endonuclease GTPase subunit 1216749 9727291 SPAP_1276 Streptococcus pneumoniae AP200 restriction endonuclease GTPase subunit YP_003876865.1 1214818 R 574093 CDS YP_003876866.1 307067900 9727292 complement(1216913..1217074) 1 NC_014494.1 Operon 574 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1217074 9727292 SPAP_1277 Streptococcus pneumoniae AP200 hypothetical protein YP_003876866.1 1216913 R 574093 CDS YP_003876867.1 307067901 9727293 complement(1217335..1217478) 1 NC_014494.1 Operon 575 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1217478 9727293 SPAP_1278 Streptococcus pneumoniae AP200 hypothetical protein YP_003876867.1 1217335 R 574093 CDS YP_003876868.1 307067902 9727294 complement(1217697..1218056) 1 NC_014494.1 Operon 576 Gene 1 COG0066 3-isopropylmalate dehydratase small subunit; 3-isopropylmalate dehydratase small subunit 1218056 9727294 SPAP_1279 Streptococcus pneumoniae AP200 3-isopropylmalate dehydratase small subunit YP_003876868.1 1217697 R 574093 CDS YP_003876869.1 307067903 9727295 complement(1218060..1218329) 1 NC_014494.1 Operon 576 Gene 2 COG3326 Predicted membrane protein; hypothetical protein 1218329 9727295 SPAP_1280 Streptococcus pneumoniae AP200 hypothetical protein YP_003876869.1 1218060 R 574093 CDS YP_003876870.1 307067904 9727296 complement(1218326..1219363) 1 NC_014494.1 Operon 576 Gene 3 COG0473 Isocitrate/isopropylmalate dehydrogenase; isocitrate/isopropylmalate dehydrogenase 1219363 9727296 SPAP_1281 Streptococcus pneumoniae AP200 isocitrate/isopropylmalate dehydrogenase YP_003876870.1 1218326 R 574093 CDS YP_003876871.1 307067905 9727297 complement(1219375..1219794) 1 NC_014494.1 Operon 576 Gene 4 COG0119 Isopropylmalate/homocitrate/citramalate synthases; isopropylmalate/homocitrate/citramalate synthase 1219794 9727297 SPAP_1282 Streptococcus pneumoniae AP200 isopropylmalate/homocitrate/citramalate synthase YP_003876871.1 1219375 R 574093 CDS YP_003876872.1 307067906 9727298 complement(1219837..1220469) 1 NC_014494.1 Operon 576 Gene 5 COG0119 Isopropylmalate/homocitrate/citramalate synthases; isopropylmalate/homocitrate/citramalate synthase 1220469 9727298 SPAP_1283 Streptococcus pneumoniae AP200 isopropylmalate/homocitrate/citramalate synthase YP_003876872.1 1219837 R 574093 CDS YP_003876873.1 307067907 9727299 complement(1220488..1221144) 1 NC_014494.1 Operon 576 Gene 6 COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein 1221144 9727299 SPAP_1284 Streptococcus pneumoniae AP200 hypothetical protein YP_003876873.1 1220488 R 574093 CDS YP_003876874.1 307067908 9727300 complement(1221188..1221820) 1 NC_014494.1 Operon 576 Gene 7 COG3142 Uncharacterized protein involved in copper resistance; hypothetical protein 1221820 9727300 SPAP_1285 Streptococcus pneumoniae AP200 hypothetical protein YP_003876874.1 1221188 R 574093 CDS YP_003876875.1 307067909 9727301 complement(1221913..1222203) 1 NC_014494.1 Operon 577 Gene 1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein 1222203 9727301 SPAP_1286 Streptococcus pneumoniae AP200 hypothetical protein YP_003876875.1 1221913 R 574093 CDS YP_003876876.1 307067910 9727302 complement(1222379..1224466) 1 NC_014494.1 Operon 578 Gene 1 COG0550 Topoisomerase IA; topoisomerase IA 1224466 9727302 SPAP_1287 Streptococcus pneumoniae AP200 topoisomerase IA YP_003876876.1 1222379 R 574093 CDS YP_003876877.1 307067911 9727303 complement(1224633..1225676) 1 NC_014494.1 Operon 579 Gene 1 COG1808 Predicted membrane protein; hypothetical protein 1225676 9727303 SPAP_1288 Streptococcus pneumoniae AP200 hypothetical protein YP_003876877.1 1224633 R 574093 CDS YP_003876878.1 307067912 9727304 1226280..1226603 1 NC_014494.1 transposase-like protein, IS1239 1226603 9727304 SPAP_1289 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876878.1 1226280 D 574093 CDS YP_003876879.1 307067913 9727305 1226603..1227214 1 NC_014494.1 transposase-like protein, IS1239 1227214 9727305 SPAP_1290 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003876879.1 1226603 D 574093 CDS YP_003876880.1 307067914 9727306 complement(1227804..1228652) 1 NC_014494.1 Operon 581 Gene 1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; putative DNA uptake Rossmann fold nucleotide-binding protein 1228652 9727306 SPAP_1291 Streptococcus pneumoniae AP200 putative DNA uptake Rossmann fold nucleotide-binding protein YP_003876880.1 1227804 R 574093 CDS YP_003876881.1 307067915 9727307 complement(1228749..1229438) 1 NC_014494.1 Operon 581 Gene 2 COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes; CTP:phosphocholine cytidylyltransferase 1229438 9727307 SPAP_1292 Streptococcus pneumoniae AP200 CTP:phosphocholine cytidylyltransferase YP_003876881.1 1228749 R 574093 CDS YP_003876882.1 307067916 9727308 complement(1229450..1230340) 1 NC_014494.1 Operon 581 Gene 3 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease 1230340 9727308 SPAP_1293 Streptococcus pneumoniae AP200 drug/metabolite transporter (DMT) superfamily permease YP_003876882.1 1229450 R 574093 CDS YP_003876883.1 307067917 9727309 complement(1230318..1231187) 1 NC_014494.1 Operon 581 Gene 4 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative choline kinase 1231187 9727309 SPAP_1294 Streptococcus pneumoniae AP200 putative choline kinase YP_003876883.1 1230318 R 574093 CDS YP_003876884.1 307067918 9727310 complement(1231204..1232226) 1 NC_014494.1 Operon 581 Gene 5 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase 1232226 9727310 SPAP_1295 Streptococcus pneumoniae AP200 threonine dehydrogenase-like Zn-dependent dehydrogenase YP_003876884.1 1231204 R 574093 CDS YP_003876885.1 307067919 9727311 complement(1232231..1232938) 1 NC_014494.1 Operon 581 Gene 6 COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 4-diphosphocytidyl-2-methyl-D-erithritol synthase 1232938 9727311 SPAP_1296 Streptococcus pneumoniae AP200 4-diphosphocytidyl-2-methyl-D-erithritol synthase YP_003876885.1 1232231 R 574093 CDS YP_003876886.1 307067920 9727312 1233274..1234761 1 NC_014494.1 Operon 582 Gene 1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen and teichoic acid exporter membrane protein 1234761 9727312 SPAP_1297 Streptococcus pneumoniae AP200 O-antigen and teichoic acid exporter membrane protein YP_003876886.1 1233274 D 574093 CDS YP_003876887.1 307067921 9727313 1234771..1235574 1 NC_014494.1 Operon 582 Gene 2 COG3475 LPS biosynthesis protein; LPS biosynthesis protein 1235574 9727313 SPAP_1298 Streptococcus pneumoniae AP200 LPS biosynthesis protein YP_003876887.1 1234771 D 574093 CDS YP_003876888.1 307067922 9727314 1235576..1236385 1 NC_014494.1 Operon 582 Gene 3 COG3475 LPS biosynthesis protein; LPS biosynthesis protein 1236385 9727314 SPAP_1299 Streptococcus pneumoniae AP200 LPS biosynthesis protein YP_003876888.1 1235576 D 574093 CDS YP_003876889.1 307067923 9727315 complement(1236660..1239836) 1 NC_014494.1 Operon 583 Gene 1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoylphosphate synthase large subunit 1239836 9727315 SPAP_1300 Streptococcus pneumoniae AP200 carbamoylphosphate synthase large subunit YP_003876889.1 1236660 R 574093 CDS YP_003876890.1 307067924 9727316 complement(1240148..1241227) 1 NC_014494.1 Operon 584 Gene 1 COG0505 Carbamoylphosphate synthase small subunit; carbamoylphosphate synthase small subunit 1241227 9727316 SPAP_1301 Streptococcus pneumoniae AP200 carbamoylphosphate synthase small subunit YP_003876890.1 1240148 R 574093 CDS YP_003876891.1 307067925 9727317 complement(1241277..1242200) 1 NC_014494.1 Operon 584 Gene 2 COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic chain 1242200 9727317 SPAP_1302 Streptococcus pneumoniae AP200 aspartate carbamoyltransferase catalytic chain YP_003876891.1 1241277 R 574093 CDS YP_003876892.1 307067926 9727318 complement(1242219..1242740) 1 NC_014494.1 Operon 584 Gene 3 COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; pyrimidine operon attenuation protein/uracil phosphoribosyltransferase 1242740 9727318 SPAP_1303 Streptococcus pneumoniae AP200 pyrimidine operon attenuation protein/uracil phosphoribosyltransferase YP_003876892.1 1242219 R 574093 CDS YP_003876893.1 307067927 9727319 complement(1242951..1243580) 1 NC_014494.1 Operon 585 Gene 1 COG0177 Predicted EndoIII-related endonuclease; putative EndoIII-related endonuclease 1243580 9727319 SPAP_1304 Streptococcus pneumoniae AP200 putative EndoIII-related endonuclease YP_003876893.1 1242951 R 574093 CDS YP_003876894.1 307067928 9727320 complement(1243580..1244122) 1 NC_014494.1 Operon 585 Gene 2 COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; putative metal-binding, possibly nucleic acid-binding protein 1244122 9727320 SPAP_1305 Streptococcus pneumoniae AP200 putative metal-binding, possibly nucleic acid-binding protein YP_003876894.1 1243580 R 574093 CDS YP_003876895.1 307067929 9727321 1244292..1244609 1 NC_014494.1 Operon 586 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1244609 9727321 SPAP_1306 Streptococcus pneumoniae AP200 hypothetical protein YP_003876895.1 1244292 D 574093 CDS YP_003876896.1 307067930 9727322 complement(1244577..1244786) 1 NC_014494.1 Operon 587 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1244786 9727322 SPAP_1307 Streptococcus pneumoniae AP200 hypothetical protein YP_003876896.1 1244577 R 574093 CDS YP_003876897.1 307067931 9727323 1244848..1246407 1 NC_014494.1 Operon 588 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 1246407 9727323 SPAP_1308 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003876897.1 1244848 D 574093 CDS YP_003876898.1 307067932 9727324 complement(1246451..1247350) 1 NC_014494.1 Operon 589 Gene 1 COG0501 Zn-dependent protease with chaperone function; Zn-dependent protease with chaperone function 1247350 9727324 SPAP_1309 Streptococcus pneumoniae AP200 Zn-dependent protease with chaperone function YP_003876898.1 1246451 R 574093 CDS YP_003876899.1 307067933 9727325 complement(1247352..1247912) 1 NC_014494.1 Operon 589 Gene 2 COG1704 Uncharacterized conserved protein; hypothetical protein 1247912 9727325 SPAP_1310 Streptococcus pneumoniae AP200 hypothetical protein YP_003876899.1 1247352 R 574093 CDS YP_003876900.1 307067934 9727326 1248006..1248719 1 NC_014494.1 Operon 590 Gene 1 COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; putative S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division 1248719 9727326 SPAP_1311 Streptococcus pneumoniae AP200 putative S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division YP_003876900.1 1248006 D 574093 CDS YP_003876901.1 307067935 9727327 1248952..1250256 1 NC_014494.1 Operon 590 Gene 2 protein supported gi|168182407|ref|ZP_02617071.1| 50S ribosomal protein L18; hypothetical protein 1250256 9727327 SPAP_1312 Streptococcus pneumoniae AP200 hypothetical protein YP_003876901.1 1248952 D 574093 CDS YP_003876902.1 307067936 9727328 complement(1250451..1252022) 1 NC_014494.1 Operon 591 Gene 1 COG0541 Signal recognition particle GTPase; signal recognition particle GTPase 1252022 9727328 SPAP_1313 Streptococcus pneumoniae AP200 signal recognition particle GTPase YP_003876902.1 1250451 R 574093 CDS YP_003876903.1 307067937 9727329 complement(1252034..1252366) 1 NC_014494.1 Operon 591 Gene 2 COG2739 Uncharacterized protein conserved in bacteria; hypothetical protein 1252366 9727329 SPAP_1314 Streptococcus pneumoniae AP200 hypothetical protein YP_003876903.1 1252034 R 574093 CDS YP_003876904.1 307067938 9727330 complement(1252457..1252834) 1 NC_014494.1 Operon 591 Gene 3 protein supported gi|149007043|ref|ZP_01830712.1| 50S ribosomal protein L19; hypothetical protein 1252834 9727330 SPAP_1315 Streptococcus pneumoniae AP200 hypothetical protein YP_003876904.1 1252457 R 574093 CDS YP_003876905.1 307067939 9727331 1252906..1254210 1 NC_014494.1 Operon 592 Gene 1 COG1078 HD superfamily phosphohydrolases; HD superfamily phosphohydrolase 1254210 9727331 SPAP_1316 Streptococcus pneumoniae AP200 HD superfamily phosphohydrolase YP_003876905.1 1252906 D 574093 CDS YP_003876906.1 307067940 9727332 1254223..1255029 1 NC_014494.1 Operon 592 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1255029 9727332 SPAP_1317 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003876906.1 1254223 D 574093 CDS YP_003876907.1 307067941 9727333 1255072..1256070 1 NC_014494.1 Operon 592 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1256070 9727333 SPAP_1318 Streptococcus pneumoniae AP200 hypothetical protein YP_003876907.1 1255072 D 574093 CDS YP_003876908.1 307067942 9727335 complement(1256351..1256698) 1 NC_014494.1 Operon 593 Gene 1 protein supported gi|15901153|ref|NP_345757.1| 50S ribosomal protein L19; hypothetical protein 1256698 9727335 SPAP_1320 Streptococcus pneumoniae AP200 hypothetical protein YP_003876908.1 1256351 R 574093 CDS YP_003876909.1 307067943 9727336 complement(1256817..1257146) 1 NC_014494.1 Operon 594 Gene 1 COG0239 Integral membrane protein possibly involved in chromosome condensation; integral membrane protein 1257146 9727336 SPAP_1321 Streptococcus pneumoniae AP200 integral membrane protein YP_003876909.1 1256817 R 574093 CDS YP_003876910.1 307067944 9727337 complement(1257140..1257514) 1 NC_014494.1 Operon 594 Gene 2 protein supported gi|15901155|ref|NP_345759.1| chromosome condensation/camphor resistance protein CrcB; hypothetical protein 1257514 9727337 SPAP_1322 Streptococcus pneumoniae AP200 hypothetical protein YP_003876910.1 1257140 R 574093 CDS YP_003876911.1 307067945 9727338 complement(1257511..1257777) 1 NC_014494.1 Operon 594 Gene 3 COG1605 Chorismate mutase; chorismate mutase 1257777 9727338 SPAP_1323 Streptococcus pneumoniae AP200 chorismate mutase YP_003876911.1 1257511 R 574093 CDS YP_003876912.1 307067946 9727339 complement(1257893..1258336) 1 NC_014494.1 Operon 595 Gene 1 COG0716 Flavodoxins; flavodoxin 1258336 9727339 SPAP_1324 Streptococcus pneumoniae AP200 flavodoxin YP_003876912.1 1257893 R 574093 CDS YP_003876913.1 307067947 9727340 1258440..1259375 1 NC_014494.1 Operon 596 Gene 1 protein supported gi|149007035|ref|ZP_01830704.1| 50S ribosomal protein L31 type B; hypothetical protein 1259375 9727340 SPAP_1325 Streptococcus pneumoniae AP200 hypothetical protein YP_003876913.1 1258440 D 574093 CDS YP_003876914.1 307067948 9727341 1259429..1259713 1 NC_014494.1 Operon 596 Gene 2 protein supported gi|111658525|ref|ZP_01409191.1| hypothetical protein SpneT_02000352; hypothetical protein 1259713 9727341 SPAP_1326 Streptococcus pneumoniae AP200 hypothetical protein YP_003876914.1 1259429 D 574093 CDS YP_003876915.1 307067949 9727342 complement(1259770..1259988) 1 NC_014494.1 Operon 597 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1259988 9727342 SPAP_1327 Streptococcus pneumoniae AP200 hypothetical protein YP_003876915.1 1259770 R 574093 CDS YP_003876916.1 307067950 9727343 complement(1260296..1260547) 1 NC_014494.1 transposase-like protein, ISSpn2 1260547 9727343 SPAP_1328 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876916.1 1260296 R 574093 CDS YP_003876917.1 307067951 9727344 complement(1260641..1260736) 1 NC_014494.1 transposase-like protein, ISSpn2 1260736 9727344 SPAP_1329 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876917.1 1260641 R 574093 CDS YP_003876918.1 307067952 9727345 1261073..1262419 1 NC_014494.1 Operon 599 Gene 1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase/leucine dehydrogenase 1262419 9727345 SPAP_1330 Streptococcus pneumoniae AP200 glutamate dehydrogenase/leucine dehydrogenase YP_003876918.1 1261073 D 574093 CDS YP_003876919.1 307067953 9727346 complement(1262925..1263095) 1 NC_014494.1 Operon 600 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1263095 9727346 SPAP_1331 Streptococcus pneumoniae AP200 hypothetical protein YP_003876919.1 1262925 R 574093 CDS YP_003876920.1 307067954 9727347 complement(1263108..1263554) 1 NC_014494.1 Operon 600 Gene 2 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter 1263554 9727347 SPAP_1332 Streptococcus pneumoniae AP200 bacteriocin/lantibiotic ABC exporter YP_003876920.1 1263108 R 574093 CDS YP_003876921.1 307067955 9727348 complement(1263703..1264092) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1264092 9727348 SPAP_1333 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876921.1 1263703 R 574093 CDS YP_003876922.1 307067956 9727349 complement(1264185..1264508) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1264508 9727349 SPAP_1334 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003876922.1 1264185 R 574093 CDS YP_003876923.1 307067957 9727350 1264764..1264994 1 NC_014494.1 transposase-like protein, ISSpn2 1264994 9727350 SPAP_1335 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876923.1 1264764 D 574093 CDS YP_003876924.1 307067958 9727351 1264942..1265463 1 NC_014494.1 Operon 602 Gene 2 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 1265463 9727351 SPAP_1336 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003876924.1 1264942 D 574093 CDS YP_003876925.1 307067959 9727352 complement(1265734..1266030) 1 NC_014494.1 Operon 603 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1266030 9727352 SPAP_1337 Streptococcus pneumoniae AP200 hypothetical protein YP_003876925.1 1265734 R 574093 CDS YP_003876926.1 307067960 9727353 complement(1266043..1266186) 1 NC_014494.1 Operon 603 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1266186 9727353 SPAP_1338 Streptococcus pneumoniae AP200 hypothetical protein YP_003876926.1 1266043 R 574093 CDS YP_003876927.1 307067961 9727354 complement(1266188..1266475) 1 NC_014494.1 Operon 603 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1266475 9727354 SPAP_1339 Streptococcus pneumoniae AP200 hypothetical protein YP_003876927.1 1266188 R 574093 CDS YP_003876928.1 307067962 9727355 1267060..1267563 1 NC_014494.1 Operon 604 Gene 1 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1267563 9727355 SPAP_1340 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876928.1 1267060 D 574093 CDS YP_003876929.1 307067963 9727356 1267572..1268411 1 NC_014494.1 Operon 604 Gene 2 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1268411 9727356 SPAP_1341 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003876929.1 1267572 D 574093 CDS YP_003876930.1 307067964 9727357 complement(1268718..1268921) 1 NC_014494.1 Operon 605 Gene 1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1268921 9727357 SPAP_1342 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876930.1 1268718 R 574093 CDS YP_003876931.1 307067965 9727358 complement(1268997..1269608) 1 NC_014494.1 Operon 605 Gene 2 COG1394 Archaeal/vacuolar-type H+-ATPase subunit D; archaeal/vacuolar-type H+-ATPase subunit D 1269608 9727358 SPAP_1343 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit D YP_003876931.1 1268997 R 574093 CDS YP_003876932.1 307067966 9727359 complement(1269631..1271016) 1 NC_014494.1 Operon 605 Gene 3 COG1156 Archaeal/vacuolar-type H+-ATPase subunit B; archaeal/vacuolar-type H+-ATPase subunit B 1271016 9727359 SPAP_1344 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit B YP_003876932.1 1269631 R 574093 CDS YP_003876933.1 307067967 9727360 complement(1271017..1272792) 1 NC_014494.1 Operon 605 Gene 4 COG1155 Archaeal/vacuolar-type H+-ATPase subunit A; archaeal/vacuolar-type H+-ATPase subunit a 1272792 9727360 SPAP_1345 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit a YP_003876933.1 1271017 R 574093 CDS YP_003876934.1 307067968 9727361 complement(1272855..1273175) 1 NC_014494.1 Operon 605 Gene 5 COG1436 Archaeal/vacuolar-type H+-ATPase subunit F; archaeal/vacuolar-type H+-ATPase subunit F 1273175 9727361 SPAP_1346 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit F YP_003876934.1 1272855 R 574093 CDS YP_003876935.1 307067969 9727362 complement(1273165..1274172) 1 NC_014494.1 Operon 605 Gene 6 COG1527 Archaeal/vacuolar-type H+-ATPase subunit C; archaeal/vacuolar-type H+-ATPase subunit C 1274172 9727362 SPAP_1347 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit C YP_003876935.1 1273165 R 574093 CDS YP_003876936.1 307067970 9727363 complement(1274237..1274818) 1 NC_014494.1 Operon 605 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 1274818 9727363 SPAP_1348 Streptococcus pneumoniae AP200 hypothetical protein YP_003876936.1 1274237 R 574093 CDS YP_003876937.1 307067971 9727364 complement(1274852..1275328) 1 NC_014494.1 Operon 605 Gene 8 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K 1275328 9727364 SPAP_1349 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K YP_003876937.1 1274852 R 574093 CDS YP_003876938.1 307067972 9727365 complement(1275385..1277334) 1 NC_014494.1 Operon 605 Gene 9 COG1269 Archaeal/vacuolar-type H+-ATPase subunit I; archaeal/vacuolar-type H+-ATPase subunit I 1277334 9727365 SPAP_1350 Streptococcus pneumoniae AP200 archaeal/vacuolar-type H+-ATPase subunit I YP_003876938.1 1275385 R 574093 CDS YP_003876939.1 307067973 9727366 complement(1277324..1277647) 1 NC_014494.1 Operon 605 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 1277647 9727366 SPAP_1351 Streptococcus pneumoniae AP200 hypothetical protein YP_003876939.1 1277324 R 574093 CDS YP_003876940.1 307067974 9727367 complement(1277672..1278562) 1 NC_014494.1 Operon 605 Gene 11 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1278562 9727367 SPAP_1352 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003876940.1 1277672 R 574093 CDS YP_003876941.1 307067975 9727368 complement(1278719..1279828) 1 NC_014494.1 Operon 606 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein 1279828 9727368 SPAP_1353 Streptococcus pneumoniae AP200 putative dehydrogenases-like protein YP_003876941.1 1278719 R 574093 CDS YP_003876942.1 307067976 9727369 complement(1279868..1282090) 1 NC_014494.1 Operon 606 Gene 2 COG4409 Neuraminidase (sialidase); neuraminidase 1282090 9727369 SPAP_1354 Streptococcus pneumoniae AP200 neuraminidase YP_003876942.1 1279868 R 574093 CDS YP_003876943.1 307067977 9727370 complement(1282092..1282550) 1 NC_014494.1 Operon 606 Gene 3 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta 1282550 9727370 SPAP_1355 Streptococcus pneumoniae AP200 beta-galactosidase subunit beta YP_003876943.1 1282092 R 574093 CDS YP_003876944.1 307067978 9727371 complement(1282569..1284110) 1 NC_014494.1 Operon 606 Gene 4 COG0591 Na+/proline symporter; Na+/proline symporter 1284110 9727371 SPAP_1356 Streptococcus pneumoniae AP200 Na+/proline symporter YP_003876944.1 1282569 R 574093 CDS YP_003876945.1 307067979 9727372 complement(1284138..1285055) 1 NC_014494.1 Operon 606 Gene 5 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase 1285055 9727372 SPAP_1357 Streptococcus pneumoniae AP200 dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_003876945.1 1284138 R 574093 CDS YP_003876946.1 307067980 9727373 complement(1285080..1285781) 1 NC_014494.1 Operon 606 Gene 6 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; putative N-acetylmannosamine-6-phosphate epimerase 1285781 9727373 SPAP_1358 Streptococcus pneumoniae AP200 putative N-acetylmannosamine-6-phosphate epimerase YP_003876946.1 1285080 R 574093 CDS YP_003876947.1 307067981 9727374 complement(1285786..1286595) 1 NC_014494.1 Operon 606 Gene 7 COG1737 Transcriptional regulators; transcriptional regulator 1286595 9727374 SPAP_1359 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876947.1 1285786 R 574093 CDS YP_003876948.1 307067982 9727375 complement(1287229..1287585) 1 NC_014494.1 Operon 607 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 1287585 9727375 SPAP_1360 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876948.1 1287229 R 574093 CDS YP_003876949.1 307067983 9727376 complement(1287678..1287821) 1 NC_014494.1 Operon 607 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1287821 9727376 SPAP_1361 Streptococcus pneumoniae AP200 hypothetical protein YP_003876949.1 1287678 R 574093 CDS YP_003876950.1 307067984 9727377 complement(1287834..1288214) 1 NC_014494.1 Operon 607 Gene 3 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 1288214 9727377 SPAP_1362 Streptococcus pneumoniae AP200 arsenate reductase-like glutaredoxin family protein YP_003876950.1 1287834 R 574093 CDS YP_003876951.1 307067985 9727378 complement(1288372..1288557) 1 NC_014494.1 Operon 608 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1288557 9727378 SPAP_1363 Streptococcus pneumoniae AP200 hypothetical protein YP_003876951.1 1288372 R 574093 CDS YP_003876952.1 307067986 9727379 complement(1288778..1289956) 1 NC_014494.1 Operon 609 Gene 1 COG0270 Site-specific DNA methylase; site-specific DNA methylase 1289956 9727379 SPAP_1364 Streptococcus pneumoniae AP200 site-specific DNA methylase YP_003876952.1 1288778 R 574093 CDS YP_003876953.1 307067987 9727380 complement(1290183..1290524) 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 1290524 9727380 SPAP_1365 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876953.1 1290183 R 574093 CDS YP_003876954.1 307067988 9727381 complement(1290499..1290876) 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 1290876 9727381 SPAP_1366 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876954.1 1290499 R 574093 CDS YP_003876955.1 307067989 9727382 complement(1291111..1291377) 1 NC_014494.1 Operon 611 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1291377 9727382 SPAP_1367 Streptococcus pneumoniae AP200 hypothetical protein YP_003876955.1 1291111 R 574093 CDS YP_003876956.1 307067990 9727383 complement(1291280..1291534) 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 1291534 9727383 SPAP_1368 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003876956.1 1291280 R 574093 CDS YP_003876957.1 307067991 9727384 complement(1291796..1291975) 1 NC_014494.1 Operon 612 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1291975 9727384 SPAP_1369 Streptococcus pneumoniae AP200 hypothetical protein YP_003876957.1 1291796 R 574093 CDS YP_003876958.1 307067992 9727385 complement(1292155..1292292) 1 NC_014494.1 Operon 613 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1292292 9727385 SPAP_1370 Streptococcus pneumoniae AP200 hypothetical protein YP_003876958.1 1292155 R 574093 CDS YP_003876959.1 307067993 9727386 complement(1292425..1293744) 1 NC_014494.1 Operon 614 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1293744 9727386 SPAP_1371 Streptococcus pneumoniae AP200 hypothetical protein YP_003876959.1 1292425 R 574093 CDS YP_003876960.1 307067994 9727387 complement(1293747..1294487) 1 NC_014494.1 Operon 614 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1294487 9727387 SPAP_1372 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003876960.1 1293747 R 574093 CDS YP_003876961.1 307067995 9727388 complement(1294502..1296109) 1 NC_014494.1 Operon 614 Gene 3 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1296109 9727388 SPAP_1373 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003876961.1 1294502 R 574093 CDS YP_003876962.1 307067996 9727389 complement(1296106..1296900) 1 NC_014494.1 Operon 614 Gene 4 COG1770 Protease II; protease II 1296900 9727389 SPAP_1374 Streptococcus pneumoniae AP200 protease II YP_003876962.1 1296106 R 574093 CDS YP_003876963.1 307067997 9727390 complement(1298079..1300577) 1 NC_014494.1 Operon 615 Gene 1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 1300577 9727390 SPAP_1375 Streptococcus pneumoniae AP200 serine/threonine protein kinase YP_003876963.1 1298079 R 574093 CDS YP_003876964.1 307067998 9727391 complement(1300867..1301004) 1 NC_014494.1 Operon 616 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1301004 9727391 SPAP_1376 Streptococcus pneumoniae AP200 hypothetical protein YP_003876964.1 1300867 R 574093 CDS YP_003876965.1 307067999 9727392 complement(1301206..1301448) 1 NC_014494.1 Operon 617 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 1301448 9727392 SPAP_1377 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876965.1 1301206 R 574093 CDS YP_003876966.1 307068000 9727393 complement(1301600..1301791) 1 NC_014494.1 Operon 618 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 1301791 9727393 SPAP_1378 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003876966.1 1301600 R 574093 CDS YP_003876967.1 307068001 9727394 complement(1301884..1302027) 1 NC_014494.1 Operon 618 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1302027 9727394 SPAP_1379 Streptococcus pneumoniae AP200 hypothetical protein YP_003876967.1 1301884 R 574093 CDS YP_003876968.1 307068002 9727395 complement(1302040..1302420) 1 NC_014494.1 Operon 618 Gene 3 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 1302420 9727395 SPAP_1380 Streptococcus pneumoniae AP200 arsenate reductase-like glutaredoxin family protein YP_003876968.1 1302040 R 574093 CDS YP_003876969.1 307068003 9727396 complement(1302413..1302664) 1 NC_014494.1 Operon 618 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1302664 9727396 SPAP_1381 Streptococcus pneumoniae AP200 hypothetical protein YP_003876969.1 1302413 R 574093 CDS YP_003876970.1 307068004 9727397 complement(1302744..1302998) 1 NC_014494.1 Operon 618 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 1302998 9727397 SPAP_1382 Streptococcus pneumoniae AP200 hypothetical protein YP_003876970.1 1302744 R 574093 CDS YP_003876971.1 307068005 9727398 complement(1302998..1303168) 1 NC_014494.1 Operon 618 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 1303168 9727398 SPAP_1383 Streptococcus pneumoniae AP200 hypothetical protein YP_003876971.1 1302998 R 574093 CDS YP_003876972.1 307068006 9727399 complement(1303354..1303737) 1 NC_014494.1 Operon 619 Gene 1 protein supported gi|15458846|gb|AAL00015.1| 50S Ribosomal protein L12; hypothetical protein 1303737 9727399 SPAP_1384 Streptococcus pneumoniae AP200 hypothetical protein YP_003876972.1 1303354 R 574093 CDS YP_003876973.1 307068007 9727400 complement(1303798..1304361) 1 NC_014494.1 Operon 619 Gene 2 protein supported gi|182684314|ref|YP_001836061.1| 50S ribosomal protein L10; hypothetical protein 1304361 9727400 SPAP_1385 Streptococcus pneumoniae AP200 hypothetical protein YP_003876973.1 1303798 R 574093 CDS YP_003876974.1 307068008 9727401 complement(1304548..1305807) 1 NC_014494.1 Operon 620 Gene 1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; cytosine deaminase-like metal-dependent hydrolase 1305807 9727401 SPAP_1386 Streptococcus pneumoniae AP200 cytosine deaminase-like metal-dependent hydrolase YP_003876974.1 1304548 R 574093 CDS YP_003876975.1 307068009 9727402 complement(1306109..1307857) 1 NC_014494.1 Operon 621 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1307857 9727402 SPAP_1387 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003876975.1 1306109 R 574093 CDS YP_003876976.1 307068010 9727403 complement(1307859..1309583) 1 NC_014494.1 Operon 621 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1309583 9727403 SPAP_1388 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003876976.1 1307859 R 574093 CDS YP_003876977.1 307068011 9727404 complement(1309641..1310579) 1 NC_014494.1 Operon 621 Gene 3 COG0225 Peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 1310579 9727404 SPAP_1389 Streptococcus pneumoniae AP200 peptide methionine sulfoxide reductase YP_003876977.1 1309641 R 574093 CDS YP_003876978.1 307068012 9727405 complement(1310919..1311788) 1 NC_014494.1 Operon 622 Gene 1 COG0083 Homoserine kinase; homoserine kinase 1311788 9727405 SPAP_1390 Streptococcus pneumoniae AP200 homoserine kinase YP_003876978.1 1310919 R 574093 CDS YP_003876979.1 307068013 9727406 complement(1311790..1313076) 1 NC_014494.1 Operon 622 Gene 2 COG0460 Homoserine dehydrogenase; homoserine dehydrogenase 1313076 9727406 SPAP_1391 Streptococcus pneumoniae AP200 homoserine dehydrogenase YP_003876979.1 1311790 R 574093 CDS YP_003876980.1 307068014 9727407 complement(1313227..1313964) 1 NC_014494.1 Operon 623 Gene 1 COG4862 Negative regulator of genetic competence, sporulation and motility; Negative regulator of genetic competence, sporulation and motility 1313964 9727407 SPAP_1392 Streptococcus pneumoniae AP200 Negative regulator of genetic competence, sporulation and motility YP_003876980.1 1313227 R 574093 CDS YP_003876981.1 307068015 9727408 complement(1314164..1315198) 1 NC_014494.1 Operon 624 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1315198 9727408 SPAP_1393 Streptococcus pneumoniae AP200 hypothetical protein YP_003876981.1 1314164 R 574093 CDS YP_003876982.1 307068016 9727409 complement(1315227..1316534) 1 NC_014494.1 Operon 624 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1316534 9727409 SPAP_1394 Streptococcus pneumoniae AP200 hypothetical protein YP_003876982.1 1315227 R 574093 CDS YP_003876983.1 307068017 9727410 complement(1316676..1317662) 1 NC_014494.1 Operon 625 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1317662 9727410 SPAP_1395 Streptococcus pneumoniae AP200 glycosyltransferase YP_003876983.1 1316676 R 574093 CDS YP_003876984.1 307068018 9727411 complement(1317664..1318764) 1 NC_014494.1 Operon 625 Gene 2 COG0438 Glycosyltransferase; glycosyltransferase 1318764 9727411 SPAP_1396 Streptococcus pneumoniae AP200 glycosyltransferase YP_003876984.1 1317664 R 574093 CDS YP_003876985.1 307068019 9727412 complement(1318757..1319593) 1 NC_014494.1 Operon 625 Gene 3 COG3475 LPS biosynthesis protein; LPS biosynthesis protein 1319593 9727412 SPAP_1397 Streptococcus pneumoniae AP200 LPS biosynthesis protein YP_003876985.1 1318757 R 574093 CDS YP_003876986.1 307068020 9727413 complement(1319881..1321155) 1 NC_014494.1 Operon 626 Gene 1 COG1316 Transcriptional regulator; transcriptional regulator 1321155 9727413 SPAP_1398 Streptococcus pneumoniae AP200 transcriptional regulator YP_003876986.1 1319881 R 574093 CDS YP_003876987.1 307068021 9727414 complement(1321152..1322000) 1 NC_014494.1 Operon 626 Gene 2 COG0077 Prephenate dehydratase; prephenate dehydratase 1322000 9727414 SPAP_1399 Streptococcus pneumoniae AP200 prephenate dehydratase YP_003876987.1 1321152 R 574093 CDS YP_003876988.1 307068022 9727415 complement(1321997..1322473) 1 NC_014494.1 Operon 626 Gene 3 COG0703 Shikimate kinase; shikimate kinase 1322473 9727415 SPAP_1400 Streptococcus pneumoniae AP200 shikimate kinase YP_003876988.1 1321997 R 574093 CDS YP_003876989.1 307068023 9727416 complement(1322466..1323761) 1 NC_014494.1 Operon 626 Gene 4 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 5-enolpyruvylshikimate-3-phosphate synthase 1323761 9727416 SPAP_1401 Streptococcus pneumoniae AP200 5-enolpyruvylshikimate-3-phosphate synthase YP_003876989.1 1322466 R 574093 CDS YP_003876990.1 307068024 9727417 complement(1323841..1324002) 1 NC_014494.1 Operon 627 Gene 1 COG3679 Uncharacterized conserved protein; hypothetical protein 1324002 9727417 SPAP_1402 Streptococcus pneumoniae AP200 hypothetical protein YP_003876990.1 1323841 R 574093 CDS YP_003876991.1 307068025 9727418 complement(1324003..1324179) 1 NC_014494.1 Operon 627 Gene 2 COG3679 Uncharacterized conserved protein; hypothetical protein 1324179 9727418 SPAP_1403 Streptococcus pneumoniae AP200 hypothetical protein YP_003876991.1 1324003 R 574093 CDS YP_003876992.1 307068026 9727419 complement(1324190..1325293) 1 NC_014494.1 Operon 627 Gene 3 COG0287 Prephenate dehydrogenase; prephenate dehydrogenase 1325293 9727419 SPAP_1404 Streptococcus pneumoniae AP200 prephenate dehydrogenase YP_003876992.1 1324190 R 574093 CDS YP_003876993.1 307068027 9727420 complement(1325303..1326469) 1 NC_014494.1 Operon 627 Gene 4 COG0082 Chorismate synthase; chorismate synthase 1326469 9727420 SPAP_1405 Streptococcus pneumoniae AP200 chorismate synthase YP_003876993.1 1325303 R 574093 CDS YP_003876994.1 307068028 9727421 complement(1326479..1327546) 1 NC_014494.1 Operon 627 Gene 5 COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthetase 1327546 9727421 SPAP_1406 Streptococcus pneumoniae AP200 3-dehydroquinate synthetase YP_003876994.1 1326479 R 574093 CDS YP_003876995.1 307068029 9727422 complement(1327565..1328419) 1 NC_014494.1 Operon 627 Gene 6 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 1328419 9727422 SPAP_1407 Streptococcus pneumoniae AP200 shikimate 5-dehydrogenase YP_003876995.1 1327565 R 574093 CDS YP_003876996.1 307068030 9727423 complement(1328409..1329086) 1 NC_014494.1 Operon 627 Gene 7 COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase 1329086 9727423 SPAP_1408 Streptococcus pneumoniae AP200 3-dehydroquinate dehydratase YP_003876996.1 1328409 R 574093 CDS YP_003876997.1 307068031 9727424 complement(1329083..1330255) 1 NC_014494.1 Operon 627 Gene 8 COG1092 Predicted SAM-dependent methyltransferases; putative SAM-dependent methyltransferase 1330255 9727424 SPAP_1409 Streptococcus pneumoniae AP200 putative SAM-dependent methyltransferase YP_003876997.1 1329083 R 574093 CDS YP_003876998.1 307068032 9727425 complement(1330930..1332564) 1 NC_014494.1 Operon 628 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1332564 9727425 SPAP_1410 Streptococcus pneumoniae AP200 hypothetical protein YP_003876998.1 1330930 R 574093 CDS YP_003876999.1 307068033 9727426 complement(1332545..1333294) 1 NC_014494.1 Operon 628 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1333294 9727426 SPAP_1411 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003876999.1 1332545 R 574093 CDS YP_003877000.1 307068034 9727427 1333473..1334927 1 NC_014494.1 Operon 629 Gene 1 COG0366 Glycosidases; glycosidase 1334927 9727427 SPAP_1412 Streptococcus pneumoniae AP200 glycosidase YP_003877000.1 1333473 D 574093 CDS YP_003877001.1 307068035 9727428 complement(1335017..1337635) 1 NC_014494.1 Operon 630 Gene 1 COG0013 Alanyl-tRNA synthetase; alanyl-tRNa synthetase 1337635 9727428 SPAP_1413 Streptococcus pneumoniae AP200 alanyl-tRNa synthetase YP_003877001.1 1335017 R 574093 CDS YP_003877002.1 307068036 9727429 complement(1337657..1338142) 1 NC_014494.1 Operon 630 Gene 2 COG4894 Uncharacterized conserved protein; hypothetical protein 1338142 9727429 SPAP_1414 Streptococcus pneumoniae AP200 hypothetical protein YP_003877002.1 1337657 R 574093 CDS YP_003877003.1 307068037 9727430 complement(1338417..1338656) 1 NC_014494.1 Operon 631 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1338656 9727430 SPAP_1415 Streptococcus pneumoniae AP200 hypothetical protein YP_003877003.1 1338417 R 574093 CDS YP_003877004.1 307068038 9727431 complement(1338714..1339346) 1 NC_014494.1 Operon 631 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 1339346 9727431 SPAP_1416 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877004.1 1338714 R 574093 CDS YP_003877005.1 307068039 9727432 complement(1339793..1340863) 1 NC_014494.1 Operon 632 Gene 1 COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine-binding periplasmic protein 1340863 9727432 SPAP_1417 Streptococcus pneumoniae AP200 spermidine/putrescine-binding periplasmic protein YP_003877005.1 1339793 R 574093 CDS YP_003877006.1 307068040 9727433 complement(1340860..1341633) 1 NC_014494.1 Operon 632 Gene 2 COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease II 1341633 9727433 SPAP_1418 Streptococcus pneumoniae AP200 spermidine/putrescine ABC transporter permease II YP_003877006.1 1340860 R 574093 CDS YP_003877007.1 307068041 9727434 complement(1341630..1342436) 1 NC_014494.1 Operon 632 Gene 3 COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine ABC transporter permease I 1342436 9727434 SPAP_1419 Streptococcus pneumoniae AP200 spermidine/putrescine ABC transporter permease I YP_003877007.1 1341630 R 574093 CDS YP_003877008.1 307068042 9727435 complement(1342417..1343574) 1 NC_014494.1 Operon 632 Gene 4 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase 1343574 9727435 SPAP_1420 Streptococcus pneumoniae AP200 spermidine/putrescine ABC transporter ATPase YP_003877008.1 1342417 R 574093 CDS YP_003877009.1 307068043 9727436 complement(1343633..1344583) 1 NC_014494.1 Operon 632 Gene 5 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase 1344583 9727436 SPAP_1421 Streptococcus pneumoniae AP200 UDP-N-acetylmuramate dehydrogenase YP_003877009.1 1343633 R 574093 CDS YP_003877010.1 307068044 9727437 complement(1344695..1345246) 1 NC_014494.1 Operon 633 Gene 1 COG4377 Predicted membrane protein; hypothetical protein 1345246 9727437 SPAP_1422 Streptococcus pneumoniae AP200 hypothetical protein YP_003877010.1 1344695 R 574093 CDS YP_003877011.1 307068045 9727438 complement(1345257..1345448) 1 NC_014494.1 Operon 633 Gene 2 COG4377 Predicted membrane protein; hypothetical protein 1345448 9727438 SPAP_1423 Streptococcus pneumoniae AP200 hypothetical protein YP_003877011.1 1345257 R 574093 CDS YP_003877012.1 307068046 9727439 complement(1345458..1346189) 1 NC_014494.1 Operon 633 Gene 3 COG3527 Alpha-acetolactate decarboxylase; alpha-acetolactate decarboxylase 1346189 9727439 SPAP_1424 Streptococcus pneumoniae AP200 alpha-acetolactate decarboxylase YP_003877012.1 1345458 R 574093 CDS YP_003877013.1 307068047 9727440 1346331..1347602 1 NC_014494.1 Operon 634 Gene 1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; MocR family transcriptional regulator 1347602 9727440 SPAP_1425 Streptococcus pneumoniae AP200 MocR family transcriptional regulator YP_003877013.1 1346331 D 574093 CDS YP_003877014.1 307068048 9727441 complement(1347622..1348437) 1 NC_014494.1 Operon 635 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 1348437 9727441 SPAP_1426 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003877014.1 1347622 R 574093 CDS YP_003877015.1 307068049 9727442 complement(1348594..1349247) 1 NC_014494.1 Operon 636 Gene 1 COG0704 Phosphate uptake regulator; phosphate uptake regulator 1349247 9727442 SPAP_1427 Streptococcus pneumoniae AP200 phosphate uptake regulator YP_003877015.1 1348594 R 574093 CDS YP_003877016.1 307068050 9727443 complement(1349259..1350017) 1 NC_014494.1 Operon 636 Gene 2 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase 1350017 9727443 SPAP_1428 Streptococcus pneumoniae AP200 phosphate ABC transporter ATPase YP_003877016.1 1349259 R 574093 CDS YP_003877017.1 307068051 9727444 complement(1350030..1350833) 1 NC_014494.1 Operon 636 Gene 3 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase 1350833 9727444 SPAP_1429 Streptococcus pneumoniae AP200 phosphate ABC transporter ATPase YP_003877017.1 1350030 R 574093 CDS YP_003877018.1 307068052 9727445 complement(1350844..1351728) 1 NC_014494.1 Operon 636 Gene 4 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1351728 9727445 SPAP_1430 Streptococcus pneumoniae AP200 phosphate ABC transporter permease YP_003877018.1 1350844 R 574093 CDS YP_003877019.1 307068053 9727446 complement(1351718..1352635) 1 NC_014494.1 Operon 636 Gene 5 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1352635 9727446 SPAP_1431 Streptococcus pneumoniae AP200 phosphate ABC transporter permease YP_003877019.1 1351718 R 574093 CDS YP_003877020.1 307068054 9727447 complement(1352635..1353513) 1 NC_014494.1 Operon 636 Gene 6 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 1353513 9727447 SPAP_1432 Streptococcus pneumoniae AP200 phosphate ABC transporter substrate-binding protein YP_003877020.1 1352635 R 574093 CDS YP_003877021.1 307068055 9727448 complement(1354087..1355391) 1 NC_014494.1 Operon 637 Gene 1 COG0144 tRNA and rRNA cytosine-C5-methylases; tRNA and rRNA cytosine-C5-methylase 1355391 9727448 SPAP_1433 Streptococcus pneumoniae AP200 tRNA and rRNA cytosine-C5-methylase YP_003877021.1 1354087 R 574093 CDS YP_003877022.1 307068056 9727449 complement(1355392..1356165) 1 NC_014494.1 Operon 637 Gene 2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; fructose-1,6-bisphosphatase-like protein 1356165 9727449 SPAP_1434 Streptococcus pneumoniae AP200 fructose-1,6-bisphosphatase-like protein YP_003877022.1 1355392 R 574093 CDS YP_003877023.1 307068057 9727450 complement(1356155..1356433) 1 NC_014494.1 Operon 637 Gene 3 COG4476 Uncharacterized protein conserved in bacteria; hypothetical protein 1356433 9727450 SPAP_1435 Streptococcus pneumoniae AP200 hypothetical protein YP_003877023.1 1356155 R 574093 CDS YP_003877024.1 307068058 9727451 complement(1356433..1356834) 1 NC_014494.1 Operon 637 Gene 4 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 1356834 9727451 SPAP_1436 Streptococcus pneumoniae AP200 arsenate reductase-like glutaredoxin family protein YP_003877024.1 1356433 R 574093 CDS YP_003877025.1 307068059 9727452 complement(1357044..1357661) 1 NC_014494.1 Operon 638 Gene 1 COG4478 Predicted membrane protein; hypothetical protein 1357661 9727452 SPAP_1437 Streptococcus pneumoniae AP200 hypothetical protein YP_003877025.1 1357044 R 574093 CDS YP_003877026.1 307068060 9727453 complement(1357651..1358424) 1 NC_014494.1 Operon 638 Gene 2 COG0647 Predicted sugar phosphatases of the HAD superfamily; putative sugar phosphatase 1358424 9727453 SPAP_1438 Streptococcus pneumoniae AP200 putative sugar phosphatase YP_003877026.1 1357651 R 574093 CDS YP_003877027.1 307068061 9727454 complement(1358435..1359172) 1 NC_014494.1 Operon 638 Gene 3 COG3884 Acyl-ACP thioesterase; acyl-ACP thioesterase 1359172 9727454 SPAP_1439 Streptococcus pneumoniae AP200 acyl-ACP thioesterase YP_003877027.1 1358435 R 574093 CDS YP_003877028.1 307068062 9727455 complement(1359177..1360307) 1 NC_014494.1 Operon 638 Gene 4 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase-like Fe-S oxidoreductases 1360307 9727455 SPAP_1440 Streptococcus pneumoniae AP200 coproporphyrinogen III oxidase-like Fe-S oxidoreductases YP_003877028.1 1359177 R 574093 CDS YP_003877029.1 307068063 9727456 complement(1360391..1360780) 1 NC_014494.1 Operon 639 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1360780 9727456 SPAP_1441 Streptococcus pneumoniae AP200 hypothetical protein YP_003877029.1 1360391 R 574093 CDS YP_003877030.1 307068064 9727457 complement(1360796..1361179) 1 NC_014494.1 Operon 639 Gene 2 COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain; hypothetical protein 1361179 9727457 SPAP_1442 Streptococcus pneumoniae AP200 hypothetical protein YP_003877030.1 1360796 R 574093 CDS YP_003877031.1 307068065 9727458 complement(1361180..1361968) 1 NC_014494.1 Operon 639 Gene 3 COG0682 Prolipoprotein diacylglyceryltransferase; prolipoprotein diacylglyceryltransferase 1361968 9727458 SPAP_1443 Streptococcus pneumoniae AP200 prolipoprotein diacylglyceryltransferase YP_003877031.1 1361180 R 574093 CDS YP_003877032.1 307068066 9727459 complement(1361961..1362896) 1 NC_014494.1 Operon 639 Gene 4 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism; serine kinase of the HPr protein, regulates carbohydrate metabolism 1362896 9727459 SPAP_1444 Streptococcus pneumoniae AP200 serine kinase of the HPr protein, regulates carbohydrate metabolism YP_003877032.1 1361961 R 574093 CDS YP_003877033.1 307068067 9727460 complement(1363026..1363226) 1 NC_014494.1 Operon 640 Gene 1 protein supported gi|15903314|ref|NP_358864.1| 30S ribosomal protein S21; hypothetical protein 1363226 9727460 SPAP_1445 Streptococcus pneumoniae AP200 hypothetical protein YP_003877033.1 1363026 R 574093 CDS YP_003877034.1 307068068 9727461 complement(1363342..1364064) 1 NC_014494.1 Operon 641 Gene 1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase 1364064 9727461 SPAP_1446 Streptococcus pneumoniae AP200 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase YP_003877034.1 1363342 R 574093 CDS YP_003877035.1 307068069 9727462 1364188..1365228 1 NC_014494.1 Operon 642 Gene 1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine:tRNA-ribosyltransferase- isomerase 1365228 9727462 SPAP_1447 Streptococcus pneumoniae AP200 S-adenosylmethionine:tRNA-ribosyltransferase- isomerase YP_003877035.1 1364188 D 574093 CDS YP_003877036.1 307068070 9727463 complement(1365777..1366166) 1 NC_014494.1 Operon 643 Gene 1 COG5263 FOG: choline binding protein; choline binding protein 1366166 9727463 SPAP_1448 Streptococcus pneumoniae AP200 choline binding protein YP_003877036.1 1365777 R 574093 CDS YP_003877037.1 307068071 9727464 complement(1366901..1367002) 1 NC_014494.1 Operon 644 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1367002 9727464 SPAP_1449 Streptococcus pneumoniae AP200 hypothetical protein YP_003877037.1 1366901 R 574093 CDS YP_003877038.1 307068072 9727465 complement(1367620..1368171) 1 NC_014494.1 Operon 645 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 1368171 9727465 SPAP_1450 Streptococcus pneumoniae AP200 acetyltransferase YP_003877038.1 1367620 R 574093 CDS YP_003877039.1 307068073 9727466 complement(1368418..1369242) 1 NC_014494.1 Operon 646 Gene 1 COG0171 NAD synthase; NAD synthase 1369242 9727466 SPAP_1451 Streptococcus pneumoniae AP200 NAD synthase YP_003877039.1 1368418 R 574093 CDS YP_003877040.1 307068074 9727467 complement(1369239..1370699) 1 NC_014494.1 Operon 646 Gene 2 COG1488 Nicotinic acid phosphoribosyltransferase; nicotinic acid phosphoribosyltransferase 1370699 9727467 SPAP_1452 Streptococcus pneumoniae AP200 nicotinic acid phosphoribosyltransferase YP_003877040.1 1369239 R 574093 CDS YP_003877041.1 307068075 9727468 complement(1370815..1371303) 1 NC_014494.1 Operon 647 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1371303 9727468 SPAP_1453 Streptococcus pneumoniae AP200 hypothetical protein YP_003877041.1 1370815 R 574093 CDS YP_003877042.1 307068076 9727469 complement(1371293..1371502) 1 NC_014494.1 Operon 647 Gene 2 COG1476 Predicted transcriptional regulators; putative transcriptional regulator 1371502 9727469 SPAP_1454 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877042.1 1371293 R 574093 CDS YP_003877043.1 307068077 9727470 complement(1371966..1372616) 1 NC_014494.1 Operon 648 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1372616 9727470 SPAP_1455 Streptococcus pneumoniae AP200 hypothetical protein YP_003877043.1 1371966 R 574093 CDS YP_003877044.1 307068078 9727471 complement(1372632..1373351) 1 NC_014494.1 Operon 648 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1373351 9727471 SPAP_1456 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003877044.1 1372632 R 574093 CDS YP_003877045.1 307068079 9727472 complement(1373858..1374583) 1 NC_014494.1 Operon 649 Gene 1 COG0826 Collagenase and related proteases; collagenase-like protease 1374583 9727472 SPAP_1457 Streptococcus pneumoniae AP200 collagenase-like protease YP_003877045.1 1373858 R 574093 CDS YP_003877046.1 307068080 9727473 complement(1374846..1375157) 1 NC_014494.1 Operon 650 Gene 1 COG4357 Uncharacterized conserved protein; hypothetical protein 1375157 9727473 SPAP_1458 Streptococcus pneumoniae AP200 hypothetical protein YP_003877046.1 1374846 R 574093 CDS YP_003877047.1 307068081 9727474 complement(1375172..1376458) 1 NC_014494.1 Operon 650 Gene 2 COG0826 Collagenase and related proteases; collagenase-like protease 1376458 9727474 SPAP_1459 Streptococcus pneumoniae AP200 collagenase-like protease YP_003877047.1 1375172 R 574093 CDS YP_003877048.1 307068082 9727475 1377082..1377231 1 NC_014494.1 Operon 651 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1377231 9727475 SPAP_1460 Streptococcus pneumoniae AP200 hypothetical protein YP_003877048.1 1377082 D 574093 CDS YP_003877049.1 307068083 9727476 1377448..1377639 1 NC_014494.1 Operon 652 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1377639 9727476 SPAP_1461 Streptococcus pneumoniae AP200 hypothetical protein YP_003877049.1 1377448 D 574093 CDS YP_003877050.1 307068084 9727477 1377636..1378826 1 NC_014494.1 Operon 652 Gene 2 COG2189 Adenine specific DNA methylase Mod; adenine specific DNa methylase Mod 1378826 9727477 SPAP_1462 Streptococcus pneumoniae AP200 adenine specific DNa methylase Mod YP_003877050.1 1377636 D 574093 CDS YP_003877051.1 307068085 9727478 1379073..1379219 1 NC_014494.1 Operon 653 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1379219 9727478 SPAP_1463 Streptococcus pneumoniae AP200 hypothetical protein YP_003877051.1 1379073 D 574093 CDS YP_003877052.1 307068086 9727479 complement(1379341..1380333) 1 NC_014494.1 Operon 654 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein 1380333 9727479 SPAP_1464 Streptococcus pneumoniae AP200 AraC-type DNA-binding domain-containing protein YP_003877052.1 1379341 R 574093 CDS YP_003877053.1 307068087 9727480 1380493..1382247 1 NC_014494.1 Operon 655 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1382247 9727480 SPAP_1465 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877053.1 1380493 D 574093 CDS YP_003877054.1 307068088 9727481 1382231..1383952 1 NC_014494.1 Operon 655 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1383952 9727481 SPAP_1466 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877054.1 1382231 D 574093 CDS YP_003877055.1 307068089 9727482 1383963..1384547 1 NC_014494.1 Operon 655 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1384547 9727482 SPAP_1467 Streptococcus pneumoniae AP200 hypothetical protein YP_003877055.1 1383963 D 574093 CDS YP_003877056.1 307068090 9727483 1384547..1385242 1 NC_014494.1 Operon 655 Gene 4 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter 1385242 9727483 SPAP_1468 Streptococcus pneumoniae AP200 cobalt ABC transporter permease CbiQ-like transporter YP_003877056.1 1384547 D 574093 CDS YP_003877057.1 307068091 9727484 1385836..1386594 1 NC_014494.1 Operon 655 Gene 5 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 1386594 9727484 SPAP_1469 Streptococcus pneumoniae AP200 cobalt ABC transporter ATPase YP_003877057.1 1385836 D 574093 CDS YP_003877058.1 307068092 9727485 complement(1387382..1387771) 1 NC_014494.1 Operon 656 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_3 1387771 9727485 SPAP_1470 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_3 YP_003877058.1 1387382 R 574093 CDS YP_003877059.1 307068093 9727486 complement(1388142..1388447) 1 NC_014494.1 Operon 657 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_3 1388447 9727486 SPAP_1471 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_3 YP_003877059.1 1388142 R 574093 CDS YP_003877060.1 307068094 9727487 complement(1388825..1389148) 1 NC_014494.1 transposase-like protein, ISSpn_AP200_7 1389148 9727487 SPAP_1472 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_7 YP_003877060.1 1388825 R 574093 CDS YP_003877061.1 307068095 9727488 complement(1389129..1389314) 1 NC_014494.1 Operon 658 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1389314 9727488 SPAP_1473 Streptococcus pneumoniae AP200 hypothetical protein YP_003877061.1 1389129 R 574093 CDS YP_003877062.1 307068096 9727489 complement(1389618..1391180) 1 NC_014494.1 Operon 659 Gene 1 COG0519 GMP synthase, PP-ATPase domain/subunit; GMP synthase 1391180 9727489 SPAP_1474 Streptococcus pneumoniae AP200 GMP synthase YP_003877062.1 1389618 R 574093 CDS YP_003877063.1 307068097 9727490 1391322..1392020 1 NC_014494.1 Operon 660 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 1392020 9727490 SPAP_1475 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877063.1 1391322 D 574093 CDS YP_003877064.1 307068098 9727491 complement(1392063..1392959) 1 NC_014494.1 Operon 661 Gene 1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease 1392959 9727491 SPAP_1476 Streptococcus pneumoniae AP200 drug/metabolite transporter (DMT) superfamily permease YP_003877064.1 1392063 R 574093 CDS YP_003877065.1 307068099 9727492 complement(1392968..1393903) 1 NC_014494.1 Operon 661 Gene 2 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase class C-like penicillin binding protein 1393903 9727492 SPAP_1477 Streptococcus pneumoniae AP200 beta-lactamase class C-like penicillin binding protein YP_003877065.1 1392968 R 574093 CDS YP_003877066.1 307068100 9727493 complement(1393900..1394625) 1 NC_014494.1 Operon 661 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1394625 9727493 SPAP_1478 Streptococcus pneumoniae AP200 hypothetical protein YP_003877066.1 1393900 R 574093 CDS YP_003877067.1 307068101 9727494 complement(1394709..1395344) 1 NC_014494.1 Operon 662 Gene 1 COG2755 Lysophospholipase L1 and related esterases; lysophospholipase l1-like esterase 1395344 9727494 SPAP_1479 Streptococcus pneumoniae AP200 lysophospholipase l1-like esterase YP_003877067.1 1394709 R 574093 CDS YP_003877068.1 307068102 9727495 complement(1395346..1396170) 1 NC_014494.1 Operon 662 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1396170 9727495 SPAP_1480 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003877068.1 1395346 R 574093 CDS YP_003877069.1 307068103 9727496 complement(1396195..1396530) 1 NC_014494.1 Operon 662 Gene 3 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamate biosynthesis protein 1396530 9727496 SPAP_1481 Streptococcus pneumoniae AP200 poly-gamma-glutamate biosynthesis protein YP_003877069.1 1396195 R 574093 CDS YP_003877070.1 307068104 9727497 complement(1396531..1397043) 1 NC_014494.1 Operon 662 Gene 4 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamate biosynthesis protein 1397043 9727497 SPAP_1482 Streptococcus pneumoniae AP200 poly-gamma-glutamate biosynthesis protein YP_003877070.1 1396531 R 574093 CDS YP_003877071.1 307068105 9727498 complement(1397137..1397259) 1 NC_014494.1 Operon 663 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1397259 9727498 SPAP_1483 Streptococcus pneumoniae AP200 hypothetical protein YP_003877071.1 1397137 R 574093 CDS YP_003877072.1 307068106 9727499 1397772..1398383 1 NC_014494.1 Operon 664 Gene 1 COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase 1398383 9727499 SPAP_1484 Streptococcus pneumoniae AP200 N-formylmethionyl-tRNA deformylase YP_003877072.1 1397772 D 574093 CDS YP_003877073.1 307068107 9727500 1398395..1399156 1 NC_014494.1 Operon 664 Gene 2 protein supported gi|163764761|ref|ZP_02171815.1| ribosomal protein S11; hypothetical protein 1399156 9727500 SPAP_1485 Streptococcus pneumoniae AP200 hypothetical protein YP_003877073.1 1398395 D 574093 CDS YP_003877074.1 307068108 9727501 complement(1399196..1400107) 1 NC_014494.1 Operon 665 Gene 1 COG0492 Thioredoxin reductase; thioredoxin reductase 1400107 9727501 SPAP_1486 Streptococcus pneumoniae AP200 thioredoxin reductase YP_003877074.1 1399196 R 574093 CDS YP_003877075.1 307068109 9727502 complement(1400173..1400397) 1 NC_014494.1 Operon 665 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1400397 9727502 SPAP_1487 Streptococcus pneumoniae AP200 hypothetical protein YP_003877075.1 1400173 R 574093 CDS YP_003877076.1 307068110 9727503 complement(1400475..1401218) 1 NC_014494.1 Operon 666 Gene 1 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 1401218 9727503 SPAP_1488 Streptococcus pneumoniae AP200 hypothetical protein YP_003877076.1 1400475 R 574093 CDS YP_003877077.1 307068111 9727504 complement(1401218..1402018) 1 NC_014494.1 Operon 666 Gene 2 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 1402018 9727504 SPAP_1489 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003877077.1 1401218 R 574093 CDS YP_003877078.1 307068112 9727505 complement(1402176..1402532) 1 NC_014494.1 Operon 667 Gene 1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 1402532 9727505 SPAP_1490 Streptococcus pneumoniae AP200 arsenate reductase-like glutaredoxin family protein YP_003877078.1 1402176 R 574093 CDS YP_003877079.1 307068113 9727506 complement(1402545..1403057) 1 NC_014494.1 Operon 667 Gene 2 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated DNA-protein cysteine methyltransferase 1403057 9727506 SPAP_1491 Streptococcus pneumoniae AP200 methylated DNA-protein cysteine methyltransferase YP_003877079.1 1402545 R 574093 CDS YP_003877080.1 307068114 9727507 complement(1403057..1403551) 1 NC_014494.1 Operon 667 Gene 3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1403551 9727507 SPAP_1492 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877080.1 1403057 R 574093 CDS YP_003877081.1 307068115 9727508 1403686..1404132 1 NC_014494.1 Operon 668 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1404132 9727508 SPAP_1493 Streptococcus pneumoniae AP200 hypothetical protein YP_003877081.1 1403686 D 574093 CDS YP_003877082.1 307068116 9727509 1404129..1404776 1 NC_014494.1 Operon 668 Gene 2 COG1272 Predicted membrane protein, hemolysin III homolog; hypothetical protein 1404776 9727509 SPAP_1494 Streptococcus pneumoniae AP200 hypothetical protein YP_003877082.1 1404129 D 574093 CDS YP_003877083.1 307068117 9727510 complement(1404797..1405378) 1 NC_014494.1 Operon 669 Gene 1 COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis; putative glutamine amidotransferase 1405378 9727510 SPAP_1495 Streptococcus pneumoniae AP200 putative glutamine amidotransferase YP_003877083.1 1404797 R 574093 CDS YP_003877084.1 307068118 9727511 complement(1405379..1406254) 1 NC_014494.1 Operon 669 Gene 2 COG0214 Pyridoxine biosynthesis enzyme; pyridoxine biosynthesis enzyme 1406254 9727511 SPAP_1496 Streptococcus pneumoniae AP200 pyridoxine biosynthesis enzyme YP_003877084.1 1405379 R 574093 CDS YP_003877085.1 307068119 9727512 complement(1406406..1407785) 1 NC_014494.1 Operon 670 Gene 1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; hypothetical protein 1407785 9727512 SPAP_1497 Streptococcus pneumoniae AP200 hypothetical protein YP_003877085.1 1406406 R 574093 CDS YP_003877086.1 307068120 9727513 1408079..1409002 1 NC_014494.1 Operon 671 Gene 1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; membrane-associated lipoprotein involved in thiamine biosynthesis 1409002 9727513 SPAP_1498 Streptococcus pneumoniae AP200 membrane-associated lipoprotein involved in thiamine biosynthesis YP_003877086.1 1408079 D 574093 CDS YP_003877087.1 307068121 9727514 1409062..1409667 1 NC_014494.1 Operon 671 Gene 2 COG0431 Predicted flavoprotein; putative flavoprotein 1409667 9727514 SPAP_1499 Streptococcus pneumoniae AP200 putative flavoprotein YP_003877087.1 1409062 D 574093 CDS YP_003877088.1 307068122 9727515 1409686..1410930 1 NC_014494.1 Operon 671 Gene 3 COG2461 Uncharacterized conserved protein; hypothetical protein 1410930 9727515 SPAP_1500 Streptococcus pneumoniae AP200 hypothetical protein YP_003877088.1 1409686 D 574093 CDS YP_003877089.1 307068123 9727516 complement(1411153..1411410) 1 NC_014494.1 Operon 672 Gene 1 COG4224 Uncharacterized protein conserved in bacteria; hypothetical protein 1411410 9727516 SPAP_1501 Streptococcus pneumoniae AP200 hypothetical protein YP_003877089.1 1411153 R 574093 CDS YP_003877090.1 307068124 9727517 complement(1411452..1413488) 1 NC_014494.1 Operon 672 Gene 2 COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 1413488 9727517 SPAP_1502 Streptococcus pneumoniae AP200 glycyl-tRNA synthetase subunit beta YP_003877090.1 1411452 R 574093 CDS YP_003877091.1 307068125 9727518 complement(1413700..1414617) 1 NC_014494.1 Operon 672 Gene 3 COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha 1414617 9727518 SPAP_1503 Streptococcus pneumoniae AP200 glycyl-tRNA synthetase subunit alpha YP_003877091.1 1413700 R 574093 CDS YP_003877092.1 307068126 9727519 complement(1414812..1415573) 1 NC_014494.1 Operon 673 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1415573 9727519 SPAP_1504 Streptococcus pneumoniae AP200 hypothetical protein YP_003877092.1 1414812 R 574093 CDS YP_003877093.1 307068127 9727520 complement(1415846..1416688) 1 NC_014494.1 Operon 674 Gene 1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 1416688 9727520 SPAP_1505 Streptococcus pneumoniae AP200 aldo/keto reductase YP_003877093.1 1415846 R 574093 CDS YP_003877094.1 307068128 9727521 complement(1416802..1418193) 1 NC_014494.1 Operon 675 Gene 1 COG0726 Predicted xylanase/chitin deacetylase; putative xylanase/chitin deacetylase 1418193 9727521 SPAP_1506 Streptococcus pneumoniae AP200 putative xylanase/chitin deacetylase YP_003877094.1 1416802 R 574093 CDS YP_003877095.1 307068129 9727522 complement(1418428..1418805) 1 NC_014494.1 Operon 676 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1418805 9727522 SPAP_1507 Streptococcus pneumoniae AP200 hypothetical protein YP_003877095.1 1418428 R 574093 CDS YP_003877096.1 307068130 9727523 1419020..1419997 1 NC_014494.1 Operon 677 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein 1419997 9727523 SPAP_1508 Streptococcus pneumoniae AP200 putative dehydrogenases-like protein YP_003877096.1 1419020 D 574093 CDS YP_003877097.1 307068131 9727524 1419994..1421076 1 NC_014494.1 Operon 677 Gene 2 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase 1421076 9727524 SPAP_1509 Streptococcus pneumoniae AP200 superfamily II DNA and RNA helicase YP_003877097.1 1419994 D 574093 CDS YP_003877098.1 307068132 9727525 complement(1421235..1421648) 1 NC_014494.1 Operon 678 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 1421648 9727525 SPAP_1510 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003877098.1 1421235 R 574093 CDS YP_003877099.1 307068133 9727526 complement(1421680..1422033) 1 NC_014494.1 transposase-like protein, ISSpn2 1422033 9727526 SPAP_1511 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003877099.1 1421680 R 574093 CDS YP_003877100.1 307068134 9727527 complement(1422057..1422188) 1 NC_014494.1 transposase-like protein, ISSpn2 1422188 9727527 SPAP_1512 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003877100.1 1422057 R 574093 CDS YP_003877101.1 307068135 9727528 complement(1422572..1423768) 1 NC_014494.1 Operon 679 Gene 1 protein supported gi|119502908|ref|ZP_01624993.1| Ribosomal protein S19; hypothetical protein 1423768 9727528 SPAP_1513 Streptococcus pneumoniae AP200 hypothetical protein YP_003877101.1 1422572 R 574093 CDS YP_003877102.1 307068136 9727529 complement(1423932..1424885) 1 NC_014494.1 transposase-like protein, IS1239 1424885 9727529 SPAP_1514 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877102.1 1423932 R 574093 CDS YP_003877103.1 307068137 9727530 complement(1425923..1426792) 1 NC_014494.1 Operon 681 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease 1426792 9727530 SPAP_1515 Streptococcus pneumoniae AP200 glycerol uptake facilitator-like permease YP_003877103.1 1425923 R 574093 CDS YP_003877104.1 307068138 9727531 complement(1427016..1427537) 1 NC_014494.1 cell wall surface anchor family protein; hypothetical protein 1427537 9727531 SPAP_1516 Streptococcus pneumoniae AP200 hypothetical protein YP_003877104.1 1427016 R 574093 CDS YP_003877105.1 307068139 9727532 complement(1427495..1428601) 1 NC_014494.1 Operon 682 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1428601 9727532 SPAP_1517 Streptococcus pneumoniae AP200 hypothetical protein YP_003877105.1 1427495 R 574093 CDS YP_003877106.1 307068140 9727533 complement(1428712..1428963) 1 NC_014494.1 Operon 683 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1428963 9727533 SPAP_1518 Streptococcus pneumoniae AP200 hypothetical protein YP_003877106.1 1428712 R 574093 CDS YP_003877107.1 307068141 9727534 complement(1429306..1429605) 1 NC_014494.1 Operon 684 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_4 1429605 9727534 SPAP_1519 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_4 YP_003877107.1 1429306 R 574093 CDS YP_003877108.1 307068142 9727535 complement(1429825..1430040) 1 NC_014494.1 Operon 685 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1430040 9727535 SPAP_1520 Streptococcus pneumoniae AP200 hypothetical protein YP_003877108.1 1429825 R 574093 CDS YP_003877109.1 307068143 9727536 1430383..1432101 1 NC_014494.1 Operon 686 Gene 1 COG1109 Phosphomannomutase; phosphomannomutase 1432101 9727536 SPAP_1521 Streptococcus pneumoniae AP200 phosphomannomutase YP_003877109.1 1430383 D 574093 CDS YP_003877110.1 307068144 9727537 1432212..1432559 1 NC_014494.1 Operon 686 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 1432559 9727537 SPAP_1522 Streptococcus pneumoniae AP200 thiol-disulfide isomerase and thioredoxin YP_003877110.1 1432212 D 574093 CDS YP_003877111.1 307068145 9727538 complement(1432838..1433674) 1 NC_014494.1 Operon 687 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 1433674 9727538 SPAP_1523 Streptococcus pneumoniae AP200 amino acid ABC transporter/signal transduction system periplasmic domain-containing protein YP_003877111.1 1432838 R 574093 CDS YP_003877112.1 307068146 9727539 complement(1433687..1434316) 1 NC_014494.1 Operon 687 Gene 2 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase 1434316 9727539 SPAP_1524 Streptococcus pneumoniae AP200 polar amino acid ABC transporter ATPase YP_003877112.1 1433687 R 574093 CDS YP_003877113.1 307068147 9727540 complement(1434326..1434967) 1 NC_014494.1 Operon 687 Gene 3 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 1434967 9727540 SPAP_1525 Streptococcus pneumoniae AP200 amino acid ABC transporter permease YP_003877113.1 1434326 R 574093 CDS YP_003877114.1 307068148 9727541 complement(1435113..1436342) 1 NC_014494.1 Operon 688 Gene 1 COG0457 FOG: TPR repeat; TPR repeat protein 1436342 9727541 SPAP_1526 Streptococcus pneumoniae AP200 TPR repeat protein YP_003877114.1 1435113 R 574093 CDS YP_003877115.1 307068149 9727542 complement(1436332..1437498) 1 NC_014494.1 Operon 688 Gene 2 COG0628 Predicted permease; putative permease 1437498 9727542 SPAP_1527 Streptococcus pneumoniae AP200 putative permease YP_003877115.1 1436332 R 574093 CDS YP_003877116.1 307068150 9727543 1437642..1438655 1 NC_014494.1 Operon 689 Gene 1 COG2706 3-carboxymuconate cyclase; 3-carboxymuconate cyclase 1438655 9727543 SPAP_1528 Streptococcus pneumoniae AP200 3-carboxymuconate cyclase YP_003877116.1 1437642 D 574093 CDS YP_003877117.1 307068151 9727544 complement(1438700..1439119) 1 NC_014494.1 Operon 690 Gene 1 COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); F0F1-type ATP synthase subunit epsilon 1439119 9727544 SPAP_1529 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit epsilon YP_003877117.1 1438700 R 574093 CDS YP_003877118.1 307068152 9727545 complement(1439130..1440536) 1 NC_014494.1 Operon 690 Gene 2 COG0055 F0F1-type ATP synthase, beta subunit; F0F1-type ATP synthase subunit beta 1440536 9727545 SPAP_1530 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit beta YP_003877118.1 1439130 R 574093 CDS YP_003877119.1 307068153 9727546 complement(1440622..1441500) 1 NC_014494.1 Operon 690 Gene 3 COG0224 F0F1-type ATP synthase, gamma subunit; F0F1-type ATP synthase subunit gamma 1441500 9727546 SPAP_1531 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit gamma YP_003877119.1 1440622 R 574093 CDS YP_003877120.1 307068154 9727547 complement(1441516..1443021) 1 NC_014494.1 Operon 690 Gene 4 COG0056 F0F1-type ATP synthase, alpha subunit; F0F1-type ATP synthase subunit alpha 1443021 9727547 SPAP_1532 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit alpha YP_003877120.1 1441516 R 574093 CDS YP_003877121.1 307068155 9727548 complement(1443036..1443572) 1 NC_014494.1 Operon 690 Gene 5 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1-type ATP synthase subunit delta 1443572 9727548 SPAP_1533 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit delta YP_003877121.1 1443036 R 574093 CDS YP_003877122.1 307068156 9727549 complement(1443572..1444066) 1 NC_014494.1 Operon 690 Gene 6 COG0711 F0F1-type ATP synthase, subunit b; F0F1-type ATP synthase subunit b 1444066 9727549 SPAP_1534 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit b YP_003877122.1 1443572 R 574093 CDS YP_003877123.1 307068157 9727550 complement(1444080..1444796) 1 NC_014494.1 Operon 690 Gene 7 COG0356 F0F1-type ATP synthase, subunit a; F0F1-type ATP synthase subunit a 1444796 9727550 SPAP_1535 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit a YP_003877123.1 1444080 R 574093 CDS YP_003877124.1 307068158 9727551 complement(1444831..1445031) 1 NC_014494.1 Operon 690 Gene 8 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K 1445031 9727551 SPAP_1536 Streptococcus pneumoniae AP200 F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K YP_003877124.1 1444831 R 574093 CDS YP_003877125.1 307068159 9727552 complement(1445106..1446116) 1 NC_014494.1 transposase-like protein, IS1239 1446116 9727552 SPAP_1537 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877125.1 1445106 R 574093 CDS YP_003877126.1 307068160 9727553 complement(1446490..1446888) 1 NC_014494.1 Operon 691 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1446888 9727553 SPAP_1538 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877126.1 1446490 R 574093 CDS YP_003877127.1 307068161 9727554 complement(1447261..1447743) 1 NC_014494.1 Operon 692 Gene 1 COG0782 Transcription elongation factor; transcription elongation factor 1447743 9727554 SPAP_1539 Streptococcus pneumoniae AP200 transcription elongation factor YP_003877127.1 1447261 R 574093 CDS YP_003877128.1 307068162 9727555 complement(1447814..1449469) 1 NC_014494.1 Operon 692 Gene 2 COG1559 Predicted periplasmic solute-binding protein; putative periplasmic solute-binding protein 1449469 9727555 SPAP_1540 Streptococcus pneumoniae AP200 putative periplasmic solute-binding protein YP_003877128.1 1447814 R 574093 CDS YP_003877129.1 307068163 9727556 complement(1449550..1450044) 1 NC_014494.1 Operon 693 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1450044 9727556 SPAP_1541 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877129.1 1449550 R 574093 CDS YP_003877130.1 307068164 9727557 complement(1450041..1450505) 1 NC_014494.1 Operon 693 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1450505 9727557 SPAP_1542 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877130.1 1450041 R 574093 CDS YP_003877131.1 307068165 9727558 complement(1450515..1451849) 1 NC_014494.1 Operon 693 Gene 3 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate-alanine ligase 1451849 9727558 SPAP_1543 Streptococcus pneumoniae AP200 UDP-N-acetylmuramate-alanine ligase YP_003877131.1 1450515 R 574093 CDS YP_003877132.1 307068166 9727559 complement(1451860..1452477) 1 NC_014494.1 Operon 693 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1452477 9727559 SPAP_1544 Streptococcus pneumoniae AP200 hypothetical protein YP_003877132.1 1451860 R 574093 CDS YP_003877133.1 307068167 9727560 complement(1452525..1455623) 1 NC_014494.1 Operon 693 Gene 5 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; superfamily II DNA/RNA helicase 1455623 9727560 SPAP_1545 Streptococcus pneumoniae AP200 superfamily II DNA/RNA helicase YP_003877133.1 1452525 R 574093 CDS YP_003877134.1 307068168 9727561 complement(1455716..1456882) 1 NC_014494.1 Operon 694 Gene 1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities 1456882 9727561 SPAP_1546 Streptococcus pneumoniae AP200 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities YP_003877134.1 1455716 R 574093 CDS YP_003877135.1 307068169 9727562 complement(1456890..1457984) 1 NC_014494.1 Operon 694 Gene 2 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase/cystathionine gamma-synthase 1457984 9727562 SPAP_1547 Streptococcus pneumoniae AP200 cystathionine beta-lyase/cystathionine gamma-synthase YP_003877135.1 1456890 R 574093 CDS YP_003877136.1 307068170 9727563 complement(1458142..1458864) 1 NC_014494.1 Operon 695 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1458864 9727563 SPAP_1548 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877136.1 1458142 R 574093 CDS YP_003877137.1 307068171 9727564 complement(1458889..1459824) 1 NC_014494.1 Operon 695 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1459824 9727564 SPAP_1549 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877137.1 1458889 R 574093 CDS YP_003877138.1 307068172 9727565 complement(1459979..1461955) 1 NC_014494.1 Operon 696 Gene 1 protein supported gi|148997067|ref|ZP_01824721.1| 30S ribosomal protein S1; hypothetical protein 1461955 9727565 SPAP_1550 Streptococcus pneumoniae AP200 hypothetical protein YP_003877138.1 1459979 R 574093 CDS YP_003877139.1 307068173 9727566 complement(1462159..1463781) 1 NC_014494.1 Operon 697 Gene 1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen and teichoic acid exporter membrane protein 1463781 9727566 SPAP_1551 Streptococcus pneumoniae AP200 O-antigen and teichoic acid exporter membrane protein YP_003877139.1 1462159 R 574093 CDS YP_003877140.1 307068174 9727567 1463887..1465332 1 NC_014494.1 Operon 698 Gene 1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 1465332 9727567 SPAP_1552 Streptococcus pneumoniae AP200 UDP-N-acetylmuramyl tripeptide synthase YP_003877140.1 1463887 D 574093 CDS YP_003877141.1 307068175 9727568 complement(1465375..1465572) 1 NC_014494.1 Operon 699 Gene 1 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein 1465572 9727568 SPAP_1553 Streptococcus pneumoniae AP200 hypothetical protein YP_003877141.1 1465375 R 574093 CDS YP_003877142.1 307068176 9727569 complement(1465673..1466269) 1 NC_014494.1 Operon 700 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1466269 9727569 SPAP_1554 Streptococcus pneumoniae AP200 hypothetical protein YP_003877142.1 1465673 R 574093 CDS YP_003877143.1 307068177 9727570 complement(1466306..1466818) 1 NC_014494.1 Operon 700 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1466818 9727570 SPAP_1555 Streptococcus pneumoniae AP200 hypothetical protein YP_003877143.1 1466306 R 574093 CDS YP_003877144.1 307068178 9727571 complement(1466904..1467839) 1 NC_014494.1 Operon 700 Gene 3 COG1227 Inorganic pyrophosphatase/exopolyphosphatase; inorganic pyrophosphatase/exopolyphosphatase 1467839 9727571 SPAP_1556 Streptococcus pneumoniae AP200 inorganic pyrophosphatase/exopolyphosphatase YP_003877144.1 1466904 R 574093 CDS YP_003877145.1 307068179 9727572 complement(1467910..1468209) 1 NC_014494.1 Operon 700 Gene 4 COG2827 Predicted endonuclease containing a URI domain; putative endonuclease containing a URI domain 1468209 9727572 SPAP_1557 Streptococcus pneumoniae AP200 putative endonuclease containing a URI domain YP_003877145.1 1467910 R 574093 CDS YP_003877146.1 307068180 9727573 complement(1468199..1468948) 1 NC_014494.1 Operon 700 Gene 5 COG4123 Predicted O-methyltransferase; putative O-methyltransferase 1468948 9727573 SPAP_1558 Streptococcus pneumoniae AP200 putative O-methyltransferase YP_003877146.1 1468199 R 574093 CDS YP_003877147.1 307068181 9727574 complement(1469002..1469361) 1 NC_014494.1 Operon 700 Gene 6 protein supported gi|55820707|ref|YP_139149.1| hypothetical protein stu0628; hypothetical protein 1469361 9727574 SPAP_1559 Streptococcus pneumoniae AP200 hypothetical protein YP_003877147.1 1469002 R 574093 CDS YP_003877148.1 307068182 9727575 complement(1469363..1470763) 1 NC_014494.1 Operon 700 Gene 7 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1470763 9727575 SPAP_1560 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003877148.1 1469363 R 574093 CDS YP_003877149.1 307068183 9727576 complement(1471058..1471297) 1 NC_014494.1 Operon 701 Gene 1 protein supported gi|15901383|ref|NP_345987.1| 30S ribosomal protein S18; hypothetical protein 1471297 9727576 SPAP_1561 Streptococcus pneumoniae AP200 hypothetical protein YP_003877149.1 1471058 R 574093 CDS YP_003877150.1 307068184 9727577 complement(1471329..1471799) 1 NC_014494.1 Operon 701 Gene 2 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein 1471799 9727577 SPAP_1562 Streptococcus pneumoniae AP200 single-stranded DNA-binding protein YP_003877150.1 1471329 R 574093 CDS YP_003877151.1 307068185 9727578 complement(1471811..1472101) 1 NC_014494.1 Operon 701 Gene 3 protein supported gi|15901385|ref|NP_345989.1| 30S ribosomal protein S6; hypothetical protein 1472101 9727578 SPAP_1563 Streptococcus pneumoniae AP200 hypothetical protein YP_003877151.1 1471811 R 574093 CDS YP_003877152.1 307068186 9727579 complement(1472254..1473597) 1 NC_014494.1 Operon 702 Gene 1 COG0017 Aspartyl/asparaginyl-tRNA synthetases; aspartyl/asparaginyl-tRNA synthetase 1473597 9727579 SPAP_1564 Streptococcus pneumoniae AP200 aspartyl/asparaginyl-tRNA synthetase YP_003877152.1 1472254 R 574093 CDS YP_003877153.1 307068187 9727580 complement(1473616..1473981) 1 NC_014494.1 Operon 702 Gene 2 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase 1473981 9727580 SPAP_1565 Streptococcus pneumoniae AP200 lactoylglutathione lyase-like lyase YP_003877153.1 1473616 R 574093 CDS YP_003877154.1 307068188 9727581 complement(1473974..1475161) 1 NC_014494.1 Operon 702 Gene 3 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase 1475161 9727581 SPAP_1566 Streptococcus pneumoniae AP200 aspartate/tyrosine/aromatic aminotransferase YP_003877154.1 1473974 R 574093 CDS YP_003877155.1 307068189 9727582 complement(1475158..1475646) 1 NC_014494.1 Operon 702 Gene 4 COG5353 Uncharacterized protein conserved in bacteria; hypothetical protein 1475646 9727582 SPAP_1567 Streptococcus pneumoniae AP200 hypothetical protein YP_003877155.1 1475158 R 574093 CDS YP_003877156.1 307068190 9727583 1475967..1476515 1 NC_014494.1 Operon 703 Gene 1 COG0431 Predicted flavoprotein; putative flavoprotein 1476515 9727583 SPAP_1568 Streptococcus pneumoniae AP200 putative flavoprotein YP_003877156.1 1475967 D 574093 CDS YP_003877157.1 307068191 9727584 complement(1476793..1477521) 1 NC_014494.1 Operon 704 Gene 1 COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 1477521 9727584 SPAP_1569 Streptococcus pneumoniae AP200 hypothetical protein YP_003877157.1 1476793 R 574093 CDS YP_003877158.1 307068192 9727585 complement(1477600..1477779) 1 NC_014494.1 Operon 704 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1477779 9727585 SPAP_1570 Streptococcus pneumoniae AP200 hypothetical protein YP_003877158.1 1477600 R 574093 CDS YP_003877159.1 307068193 9727586 complement(1477931..1479526) 1 NC_014494.1 Operon 705 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1479526 9727586 SPAP_1571 Streptococcus pneumoniae AP200 hypothetical protein YP_003877159.1 1477931 R 574093 CDS YP_003877160.1 307068194 9727587 complement(1479538..1479948) 1 NC_014494.1 Operon 705 Gene 2 COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase 1479948 9727587 SPAP_1572 Streptococcus pneumoniae AP200 N-formylmethionyl-tRNA deformylase YP_003877160.1 1479538 R 574093 CDS YP_003877161.1 307068195 9727588 complement(1480064..1480855) 1 NC_014494.1 Operon 706 Gene 1 COG0625 Glutathione S-transferase; glutathione S-transferase 1480855 9727588 SPAP_1573 Streptococcus pneumoniae AP200 glutathione S-transferase YP_003877161.1 1480064 R 574093 CDS YP_003877162.1 307068196 9727589 complement(1480868..1483564) 1 NC_014494.1 Operon 706 Gene 2 COG0474 Cation transport ATPase; cation transport ATPase 1483564 9727589 SPAP_1574 Streptococcus pneumoniae AP200 cation transport ATPase YP_003877162.1 1480868 R 574093 CDS YP_003877163.1 307068197 9727590 1483868..1485052 1 NC_014494.1 Operon 707 Gene 1 COG0053 Predicted Co/Zn/Cd cation transporters; putative Co/Zn/Cd cation transporter 1485052 9727590 SPAP_1575 Streptococcus pneumoniae AP200 putative Co/Zn/Cd cation transporter YP_003877163.1 1483868 D 574093 CDS YP_003877164.1 307068198 9727591 complement(1485195..1487066) 1 NC_014494.1 Operon 708 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 1487066 9727591 SPAP_1576 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003877164.1 1485195 R 574093 CDS YP_003877165.1 307068199 9727592 complement(1487063..1488262) 1 NC_014494.1 Operon 708 Gene 2 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; tRNA nucleotidyltransferase/poly(A) polymerase 1488262 9727592 SPAP_1577 Streptococcus pneumoniae AP200 tRNA nucleotidyltransferase/poly(A) polymerase YP_003877165.1 1487063 R 574093 CDS YP_003877166.1 307068200 9727593 complement(1488259..1489026) 1 NC_014494.1 Operon 708 Gene 3 COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase 1489026 9727593 SPAP_1578 Streptococcus pneumoniae AP200 dihydrodipicolinate reductase YP_003877166.1 1488259 R 574093 CDS YP_003877167.1 307068201 9727594 complement(1489292..1490140) 1 NC_014494.1 Operon 709 Gene 1 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein 1490140 9727594 SPAP_1579 Streptococcus pneumoniae AP200 hypothetical protein YP_003877167.1 1489292 R 574093 CDS YP_003877168.1 307068202 9727595 complement(1490142..1490528) 1 NC_014494.1 Operon 709 Gene 2 COG4835 Uncharacterized protein conserved in bacteria; hypothetical protein 1490528 9727595 SPAP_1580 Streptococcus pneumoniae AP200 hypothetical protein YP_003877168.1 1490142 R 574093 CDS YP_003877169.1 307068203 9727596 complement(1490590..1491942) 1 NC_014494.1 Operon 709 Gene 3 COG1109 Phosphomannomutase; phosphomannomutase 1491942 9727596 SPAP_1581 Streptococcus pneumoniae AP200 phosphomannomutase YP_003877169.1 1490590 R 574093 CDS YP_003877170.1 307068204 9727597 complement(1491966..1492745) 1 NC_014494.1 Operon 709 Gene 4 COG4856 Uncharacterized protein conserved in bacteria; hypothetical protein 1492745 9727597 SPAP_1582 Streptococcus pneumoniae AP200 hypothetical protein YP_003877170.1 1491966 R 574093 CDS YP_003877171.1 307068205 9727598 complement(1492732..1493589) 1 NC_014494.1 Operon 709 Gene 5 COG1624 Uncharacterized conserved protein; hypothetical protein 1493589 9727598 SPAP_1583 Streptococcus pneumoniae AP200 hypothetical protein YP_003877171.1 1492732 R 574093 CDS YP_003877172.1 307068206 9727599 1493725..1494690 1 NC_014494.1 Operon 710 Gene 1 COG0492 Thioredoxin reductase; thioredoxin reductase 1494690 9727599 SPAP_1584 Streptococcus pneumoniae AP200 thioredoxin reductase YP_003877172.1 1493725 D 574093 CDS YP_003877173.1 307068207 9727600 complement(1494724..1495635) 1 NC_014494.1 Operon 711 Gene 1 COG1481 Uncharacterized protein conserved in bacteria; hypothetical protein 1495635 9727600 SPAP_1585 Streptococcus pneumoniae AP200 hypothetical protein YP_003877173.1 1494724 R 574093 CDS YP_003877174.1 307068208 9727601 complement(1495632..1496609) 1 NC_014494.1 Operon 711 Gene 2 COG0391 Uncharacterized conserved protein; hypothetical protein 1496609 9727601 SPAP_1586 Streptococcus pneumoniae AP200 hypothetical protein YP_003877174.1 1495632 R 574093 CDS YP_003877175.1 307068209 9727602 complement(1496606..1497496) 1 NC_014494.1 Operon 711 Gene 3 COG1660 Predicted P-loop-containing kinase; putative P-loop-containing kinase 1497496 9727602 SPAP_1587 Streptococcus pneumoniae AP200 putative P-loop-containing kinase YP_003877175.1 1496606 R 574093 CDS YP_003877176.1 307068210 9727603 complement(1497548..1497928) 1 NC_014494.1 Operon 712 Gene 1 COG0251 Putative translation initiation inhibitor, yjgF family; putative translation initiation inhibitor 1497928 9727603 SPAP_1588 Streptococcus pneumoniae AP200 putative translation initiation inhibitor YP_003877176.1 1497548 R 574093 CDS YP_003877177.1 307068211 9727604 complement(1497939..1498526) 1 NC_014494.1 Operon 712 Gene 2 COG0218 Predicted GTPase; putative GTPase 1498526 9727604 SPAP_1589 Streptococcus pneumoniae AP200 putative GTPase YP_003877177.1 1497939 R 574093 CDS YP_003877178.1 307068212 9727605 complement(1498535..1499767) 1 NC_014494.1 Operon 712 Gene 3 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease Clp, ATPase subunit 1499767 9727605 SPAP_1590 Streptococcus pneumoniae AP200 ATP-dependent protease Clp, ATPase subunit YP_003877178.1 1498535 R 574093 CDS YP_003877179.1 307068213 9727606 complement(1499799..1499969) 1 NC_014494.1 Operon 712 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1499969 9727606 SPAP_1591 Streptococcus pneumoniae AP200 hypothetical protein YP_003877179.1 1499799 R 574093 CDS YP_003877180.1 307068214 9727607 complement(1499969..1500475) 1 NC_014494.1 Operon 712 Gene 5 COG0262 Dihydrofolate reductase; dihydrofolate reductase 1500475 9727607 SPAP_1592 Streptococcus pneumoniae AP200 dihydrofolate reductase YP_003877180.1 1499969 R 574093 CDS YP_003877181.1 307068215 9727608 complement(1500605..1501123) 1 NC_014494.1 Operon 713 Gene 1 COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA-binding ferritin-like protein 1501123 9727608 SPAP_1593 Streptococcus pneumoniae AP200 DNA-binding ferritin-like protein YP_003877181.1 1500605 R 574093 CDS YP_003877182.1 307068216 9727609 complement(1501619..1503091) 1 NC_014494.1 Operon 714 Gene 1 COG5263 FOG: Glucan-binding domain (YG repeat); glucan-binding domain-containing protein 1503091 9727609 SPAP_1594 Streptococcus pneumoniae AP200 glucan-binding domain-containing protein YP_003877182.1 1501619 R 574093 CDS YP_003877183.1 307068217 9727610 complement(1503162..1503920) 1 NC_014494.1 Operon 714 Gene 2 COG0149 Triosephosphate isomerase; triosephosphate isomerase 1503920 9727610 SPAP_1595 Streptococcus pneumoniae AP200 triosephosphate isomerase YP_003877183.1 1503162 R 574093 CDS YP_003877184.1 307068218 9727611 complement(1504018..1504695) 1 NC_014494.1 Operon 715 Gene 1 COG3935 Putative primosome component and related proteins; putative primosome component-like protein 1504695 9727611 SPAP_1596 Streptococcus pneumoniae AP200 putative primosome component-like protein YP_003877184.1 1504018 R 574093 CDS YP_003877185.1 307068219 9727612 complement(1504704..1505648) 1 NC_014494.1 Operon 715 Gene 2 COG1897 Homoserine trans-succinylase; homoserine trans-succinylase 1505648 9727612 SPAP_1597 Streptococcus pneumoniae AP200 homoserine trans-succinylase YP_003877185.1 1504704 R 574093 CDS YP_003877186.1 307068220 9727613 1505688..1505843 1 NC_014494.1 Operon 716 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1505843 9727613 SPAP_1598 Streptococcus pneumoniae AP200 hypothetical protein YP_003877186.1 1505688 D 574093 CDS YP_003877187.1 307068221 9727614 complement(1505830..1506342) 1 NC_014494.1 Operon 717 Gene 1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein 1506342 9727614 SPAP_1599 Streptococcus pneumoniae AP200 adenine/guanine phosphoribosyltransferases-like PRPP-binding protein YP_003877187.1 1505830 R 574093 CDS YP_003877188.1 307068222 9727615 complement(1506429..1507187) 1 NC_014494.1 Operon 717 Gene 2 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 1507187 9727615 SPAP_1600 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003877188.1 1506429 R 574093 CDS YP_003877189.1 307068223 9727616 complement(1507688..1508818) 1 NC_014494.1 Operon 718 Gene 1 COG3839 ABC-type sugar transport systems, ATPase components; sugar ABC transporter ATPase 1508818 9727616 SPAP_1601 Streptococcus pneumoniae AP200 sugar ABC transporter ATPase YP_003877189.1 1507688 R 574093 CDS YP_003877190.1 307068224 9727618 complement(1509268..1509843) 1 NC_014494.1 Operon 719 Gene 2 COG1335 Amidases related to nicotinamidase; amidase 1509843 9727618 SPAP_1604 Streptococcus pneumoniae AP200 amidase YP_003877190.1 1509268 R 574093 CDS YP_003877191.1 307068225 9727619 complement(1509843..1510631) 1 NC_014494.1 Operon 719 Gene 3 COG4465 Pleiotropic transcriptional repressor; pleiotropic transcriptional repressor 1510631 9727619 SPAP_1605 Streptococcus pneumoniae AP200 pleiotropic transcriptional repressor YP_003877191.1 1509843 R 574093 CDS YP_003877192.1 307068226 9727620 complement(1510750..1511703) 1 NC_014494.1 transposase-like protein, IS1239 1511703 9727620 SPAP_1606 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877192.1 1510750 R 574093 CDS YP_003877193.1 307068227 9727621 complement(1512140..1513714) 1 NC_014494.1 Operon 721 Gene 1 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase 1513714 9727621 SPAP_1607 Streptococcus pneumoniae AP200 superfamily II DNA and RNA helicase YP_003877193.1 1512140 R 574093 CDS YP_003877194.1 307068228 9727622 complement(1513913..1515139) 1 NC_014494.1 Operon 722 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 1515139 9727622 SPAP_1608 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003877194.1 1513913 R 574093 CDS YP_003877195.1 307068229 9727623 1515333..1516649 1 NC_014494.1 Operon 723 Gene 1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein 1516649 9727623 SPAP_1609 Streptococcus pneumoniae AP200 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein YP_003877195.1 1515333 D 574093 CDS YP_003877196.1 307068230 9727624 1516748..1518091 1 NC_014494.1 Operon 723 Gene 2 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 1518091 9727624 SPAP_1610 Streptococcus pneumoniae AP200 UDP-N-acetylmuramyl tripeptide synthase YP_003877196.1 1516748 D 574093 CDS YP_003877197.1 307068231 9727625 1518091..1518873 1 NC_014494.1 Operon 723 Gene 3 COG3442 Predicted glutamine amidotransferase; putative glutamine amidotransferase 1518873 9727625 SPAP_1611 Streptococcus pneumoniae AP200 putative glutamine amidotransferase YP_003877197.1 1518091 D 574093 CDS YP_003877198.1 307068232 9727626 1518999..1520081 1 NC_014494.1 Operon 724 Gene 1 COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 1520081 9727626 SPAP_1612 Streptococcus pneumoniae AP200 Xaa-Pro aminopeptidase YP_003877198.1 1518999 D 574093 CDS YP_003877199.1 307068233 9727627 1520029..1520277 1 NC_014494.1 Operon 724 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1520277 9727627 SPAP_1613 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877199.1 1520029 D 574093 CDS YP_003877200.1 307068234 9727628 complement(1520494..1521228) 1 NC_014494.1 Operon 725 Gene 1 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1521228 9727628 SPAP_1614 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003877200.1 1520494 R 574093 CDS YP_003877201.1 307068235 9727629 complement(1521228..1521395) 1 NC_014494.1 Operon 725 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1521395 9727629 SPAP_1615 Streptococcus pneumoniae AP200 hypothetical protein YP_003877201.1 1521228 R 574093 CDS YP_003877202.1 307068236 9727630 complement(1521558..1521803) 1 NC_014494.1 Operon 726 Gene 1 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1521803 9727630 SPAP_1616 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn1 ISSpn3 YP_003877202.1 1521558 R 574093 CDS YP_003877203.1 307068237 9727631 complement(1521968..1522429) 1 NC_014494.1 Operon 727 Gene 1 COG4720 Predicted membrane protein; hypothetical protein 1522429 9727631 SPAP_1617 Streptococcus pneumoniae AP200 hypothetical protein YP_003877203.1 1521968 R 574093 CDS YP_003877204.1 307068238 9727632 complement(1522407..1523180) 1 NC_014494.1 Operon 727 Gene 2 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1523180 9727632 SPAP_1618 Streptococcus pneumoniae AP200 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase YP_003877204.1 1522407 R 574093 CDS YP_003877205.1 307068239 9727633 complement(1523170..1523919) 1 NC_014494.1 Operon 727 Gene 3 COG0101 Pseudouridylate synthase; pseudouridylate synthase 1523919 9727633 SPAP_1619 Streptococcus pneumoniae AP200 pseudouridylate synthase YP_003877205.1 1523170 R 574093 CDS YP_003877206.1 307068240 9727634 1524099..1524260 1 NC_014494.1 Operon 728 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1524260 9727634 SPAP_1620 Streptococcus pneumoniae AP200 hypothetical protein YP_003877206.1 1524099 D 574093 CDS YP_003877207.1 307068241 9727635 complement(1524232..1525383) 1 NC_014494.1 Operon 729 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 1525383 9727635 SPAP_1621 Streptococcus pneumoniae AP200 major facilitator superfamily permease YP_003877207.1 1524232 R 574093 CDS YP_003877208.1 307068242 9727636 complement(1525623..1526252) 1 NC_014494.1 Operon 730 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1526252 9727636 SPAP_1622 Streptococcus pneumoniae AP200 hypothetical protein YP_003877208.1 1525623 R 574093 CDS YP_003877209.1 307068243 9727637 complement(1526255..1526593) 1 NC_014494.1 Operon 730 Gene 2 COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; hypothetical protein 1526593 9727637 SPAP_1623 Streptococcus pneumoniae AP200 hypothetical protein YP_003877209.1 1526255 R 574093 CDS YP_003877210.1 307068244 9727638 complement(1526724..1527395) 1 NC_014494.1 Operon 731 Gene 1 COG0283 Cytidylate kinase; cytidylate kinase 1527395 9727638 SPAP_1624 Streptococcus pneumoniae AP200 cytidylate kinase YP_003877210.1 1526724 R 574093 CDS YP_003877211.1 307068245 9727639 complement(1527404..1527880) 1 NC_014494.1 Operon 731 Gene 2 protein supported gi|148997664|ref|ZP_01825228.1| hypothetical protein CGSSp11BS70_02114; hypothetical protein 1527880 9727639 SPAP_1625 Streptococcus pneumoniae AP200 hypothetical protein YP_003877211.1 1527404 R 574093 CDS YP_003877212.1 307068246 9727640 1527925..1528137 1 NC_014494.1 Operon 732 Gene 1 COG1141 Ferredoxin; ferredoxin 1528137 9727640 SPAP_1626 Streptococcus pneumoniae AP200 ferredoxin YP_003877212.1 1527925 D 574093 CDS YP_003877213.1 307068247 9727641 complement(1528188..1529150) 1 NC_014494.1 Operon 733 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1529150 9727641 SPAP_1627 Streptococcus pneumoniae AP200 glycosyltransferase YP_003877213.1 1528188 R 574093 CDS YP_003877214.1 307068248 9727642 complement(1529155..1530174) 1 NC_014494.1 Operon 733 Gene 2 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1530174 9727642 SPAP_1628 Streptococcus pneumoniae AP200 UDP-glucose 4-epimerase YP_003877214.1 1529155 R 574093 CDS YP_003877215.1 307068249 9727643 complement(1530430..1531533) 1 NC_014494.1 Operon 734 Gene 1 COG0665 Glycine/D-amino acid oxidases (deaminating); glycine/D-amino acid oxidase 1531533 9727643 SPAP_1629 Streptococcus pneumoniae AP200 glycine/D-amino acid oxidase YP_003877215.1 1530430 R 574093 CDS YP_003877216.1 307068250 9727644 complement(1531550..1532347) 1 NC_014494.1 Operon 734 Gene 2 COG0327 Uncharacterized conserved protein; hypothetical protein 1532347 9727644 SPAP_1630 Streptococcus pneumoniae AP200 hypothetical protein YP_003877216.1 1531550 R 574093 CDS YP_003877217.1 307068251 9727645 complement(1532444..1533013) 1 NC_014494.1 Operon 734 Gene 3 COG2384 Predicted SAM-dependent methyltransferase; putative SAM-dependent methyltransferase 1533013 9727645 SPAP_1631 Streptococcus pneumoniae AP200 putative SAM-dependent methyltransferase YP_003877217.1 1532444 R 574093 CDS YP_003877218.1 307068252 9727646 complement(1533115..1535451) 1 NC_014494.1 Operon 735 Gene 1 COG0474 Cation transport ATPase; cation transport ATPase 1535451 9727646 SPAP_1632 Streptococcus pneumoniae AP200 cation transport ATPase YP_003877218.1 1533115 R 574093 CDS YP_003877219.1 307068253 9727647 1535584..1536333 1 NC_014494.1 Operon 736 Gene 1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1536333 9727647 SPAP_1633 Streptococcus pneumoniae AP200 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_003877219.1 1535584 D 574093 CDS YP_003877220.1 307068254 9727648 complement(1536626..1537240) 1 NC_014494.1 Operon 737 Gene 1 COG4300 Predicted permease, cadmium resistance protein; putative cadmium resistance permease 1537240 9727648 SPAP_1634 Streptococcus pneumoniae AP200 putative cadmium resistance permease YP_003877220.1 1536626 R 574093 CDS YP_003877221.1 307068255 9727649 complement(1538055..1538324) 1 NC_014494.1 Operon 738 Gene 1 protein supported gi|15901462|ref|NP_346066.1| 30S ribosomal protein S15; 30S ribosomal protein S15 1538324 9727649 SPAP_1635 Streptococcus pneumoniae AP200 30S ribosomal protein S15 YP_003877221.1 1538055 R 574093 CDS YP_003877222.1 307068256 9727650 complement(1538465..1539094) 1 NC_014494.1 Operon 739 Gene 1 COG2910 Putative NADH-flavin reductase; putative NADH-flavin reductase 1539094 9727650 SPAP_1636 Streptococcus pneumoniae AP200 putative NADH-flavin reductase YP_003877222.1 1538465 R 574093 CDS YP_003877223.1 307068257 9727651 1539331..1539495 1 NC_014494.1 Operon 740 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1539495 9727651 SPAP_1637 Streptococcus pneumoniae AP200 hypothetical protein YP_003877223.1 1539331 D 574093 CDS YP_003877224.1 307068258 9727652 1539951..1540172 1 NC_014494.1 Operon 741 Gene 1 protein supported gi|148997678|ref|ZP_01825242.1| 30S ribosomal protein S15; hypothetical protein 1540172 9727652 SPAP_1638 Streptococcus pneumoniae AP200 hypothetical protein YP_003877224.1 1539951 D 574093 CDS YP_003877225.1 307068259 9727653 1540332..1542275 1 NC_014494.1 Operon 741 Gene 2 COG0441 Threonyl-tRNA synthetase; threonyl-tRNA synthetase 1542275 9727653 SPAP_1639 Streptococcus pneumoniae AP200 threonyl-tRNA synthetase YP_003877225.1 1540332 D 574093 CDS YP_003877226.1 307068260 9727654 complement(1542324..1543109) 1 NC_014494.1 Operon 742 Gene 1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 1543109 9727654 SPAP_1640 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003877226.1 1542324 R 574093 CDS YP_003877227.1 307068261 9727655 complement(1543291..1543968) 1 NC_014494.1 Operon 742 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1543968 9727655 SPAP_1641 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003877227.1 1543291 R 574093 CDS YP_003877228.1 307068262 9727656 1544124..1545197 1 NC_014494.1 Operon 743 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1545197 9727656 SPAP_1642 Streptococcus pneumoniae AP200 hypothetical protein YP_003877228.1 1544124 D 574093 CDS YP_003877229.1 307068263 9727657 complement(1545288..1545590) 1 NC_014494.1 Operon 744 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1545590 9727657 SPAP_1643 Streptococcus pneumoniae AP200 hypothetical protein YP_003877229.1 1545288 R 574093 CDS YP_003877230.1 307068264 9727658 complement(1545659..1546096) 1 NC_014494.1 Operon 744 Gene 2 COG1959 Predicted transcriptional regulator; putative transcriptional regulator 1546096 9727658 SPAP_1644 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877230.1 1545659 R 574093 CDS YP_003877231.1 307068265 9727659 complement(1546172..1547014) 1 NC_014494.1 Operon 744 Gene 3 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase 1547014 9727659 SPAP_1645 Streptococcus pneumoniae AP200 diadenosine tetraphosphatase-like serine/threonine protein phosphatase YP_003877231.1 1546172 R 574093 CDS YP_003877232.1 307068266 9727660 1547126..1547776 1 NC_014494.1 Operon 745 Gene 1 COG1321 Mn-dependent transcriptional regulator; Mn-dependent transcriptional regulator 1547776 9727660 SPAP_1646 Streptococcus pneumoniae AP200 Mn-dependent transcriptional regulator YP_003877232.1 1547126 D 574093 CDS YP_003877233.1 307068267 9727661 1547894..1548601 1 NC_014494.1 Operon 746 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1548601 9727661 SPAP_1647 Streptococcus pneumoniae AP200 hypothetical protein YP_003877233.1 1547894 D 574093 CDS YP_003877234.1 307068268 9727662 1548732..1549145 1 NC_014494.1 Operon 747 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1549145 9727662 SPAP_1648 Streptococcus pneumoniae AP200 hypothetical protein YP_003877234.1 1548732 D 574093 CDS YP_003877235.1 307068269 9727663 complement(1549128..1549298) 1 NC_014494.1 Operon 748 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1549298 9727663 SPAP_1649 Streptococcus pneumoniae AP200 hypothetical protein YP_003877235.1 1549128 R 574093 CDS YP_003877236.1 307068270 9727664 1549416..1549577 1 NC_014494.1 Operon 749 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1549577 9727664 SPAP_1650 Streptococcus pneumoniae AP200 hypothetical protein YP_003877236.1 1549416 D 574093 CDS YP_003877237.1 307068271 9727665 complement(1549616..1550059) 1 NC_014494.1 Operon 750 Gene 1 COG1490 D-Tyr-tRNAtyr deacylase; D-Tyr-tRNAtyr deacylase 1550059 9727665 SPAP_1651 Streptococcus pneumoniae AP200 D-Tyr-tRNAtyr deacylase YP_003877237.1 1549616 R 574093 CDS YP_003877238.1 307068272 9727666 complement(1550089..1552311) 1 NC_014494.1 Operon 750 Gene 2 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; guanosine polyphosphate pyrophosphohydrolase/synthetase 1552311 9727666 SPAP_1652 Streptococcus pneumoniae AP200 guanosine polyphosphate pyrophosphohydrolase/synthetase YP_003877238.1 1550089 R 574093 CDS YP_003877239.1 307068273 9727667 1552807..1552965 1 NC_014494.1 Operon 751 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1552965 9727667 SPAP_1653 Streptococcus pneumoniae AP200 hypothetical protein YP_003877239.1 1552807 D 574093 CDS YP_003877240.1 307068274 9727668 1553305..1553934 1 NC_014494.1 Operon 752 Gene 1 COG0491 Zn-dependent hydrolases, including glyoxylases; Zn-dependent hydrolase, including glyoxylases 1553934 9727668 SPAP_1654 Streptococcus pneumoniae AP200 Zn-dependent hydrolase, including glyoxylases YP_003877240.1 1553305 D 574093 CDS YP_003877241.1 307068275 9727669 complement(1554056..1555948) 1 NC_014494.1 Operon 753 Gene 1 COG3590 Predicted metalloendopeptidase; putative metalloendopeptidase 1555948 9727669 SPAP_1655 Streptococcus pneumoniae AP200 putative metalloendopeptidase YP_003877241.1 1554056 R 574093 CDS YP_003877242.1 307068276 9727670 1556239..1556961 1 NC_014494.1 Operon 754 Gene 1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn/Zn ABC transporter ATPase 1556961 9727670 SPAP_1656 Streptococcus pneumoniae AP200 Mn/Zn ABC transporter ATPase YP_003877242.1 1556239 D 574093 CDS YP_003877243.1 307068277 9727671 1556958..1557806 1 NC_014494.1 Operon 754 Gene 2 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease 1557806 9727671 SPAP_1657 Streptococcus pneumoniae AP200 Mn2+/Zn2+ ABC transporter permease YP_003877243.1 1556958 D 574093 CDS YP_003877244.1 307068278 9727672 1557838..1558767 1 NC_014494.1 Operon 754 Gene 3 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin 1558767 9727672 SPAP_1658 Streptococcus pneumoniae AP200 metal ion ABC transporter periplasmic protein/surface adhesin YP_003877244.1 1557838 D 574093 CDS YP_003877245.1 307068279 9727673 1558890..1559381 1 NC_014494.1 Operon 755 Gene 1 COG2077 Peroxiredoxin; peroxiredoxin 1559381 9727673 SPAP_1659 Streptococcus pneumoniae AP200 peroxiredoxin YP_003877245.1 1558890 D 574093 CDS YP_003877246.1 307068280 9727674 complement(1559477..1562185) 1 NC_014494.1 Operon 756 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 1562185 9727674 SPAP_1660 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003877246.1 1559477 R 574093 CDS YP_003877247.1 307068281 9727675 complement(1562187..1562888) 1 NC_014494.1 Operon 756 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1562888 9727675 SPAP_1661 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003877247.1 1562187 R 574093 CDS YP_003877248.1 307068282 9727676 complement(1563160..1565550) 1 NC_014494.1 Operon 757 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1565550 9727676 SPAP_1662 Streptococcus pneumoniae AP200 hypothetical protein YP_003877248.1 1563160 R 574093 CDS YP_003877249.1 307068283 9727677 complement(1565603..1566295) 1 NC_014494.1 Operon 757 Gene 2 COG0588 Phosphoglycerate mutase 1; phosphoglycerate mutase 1566295 9727677 SPAP_1663 Streptococcus pneumoniae AP200 phosphoglycerate mutase YP_003877249.1 1565603 R 574093 CDS YP_003877250.1 307068284 9727678 complement(1566910..1567170) 1 NC_014494.1 Operon 758 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1567170 9727678 SPAP_1664 Streptococcus pneumoniae AP200 hypothetical protein YP_003877250.1 1566910 R 574093 CDS YP_003877251.1 307068285 9727679 complement(1567618..1570410) 1 NC_014494.1 Operon 759 Gene 1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1570410 9727679 SPAP_1665 Streptococcus pneumoniae AP200 isoleucyl-tRNA synthetase YP_003877251.1 1567618 R 574093 CDS YP_003877252.1 307068286 9727680 complement(1570758..1571546) 1 NC_014494.1 Operon 760 Gene 1 COG3599 Cell division initiation protein; cell division initiation protein 1571546 9727680 SPAP_1666 Streptococcus pneumoniae AP200 cell division initiation protein YP_003877252.1 1570758 R 574093 CDS YP_003877253.1 307068287 9727681 complement(1571555..1572340) 1 NC_014494.1 Operon 760 Gene 2 protein supported gi|15901497|ref|NP_346101.1| ylmH protein; hypothetical protein 1572340 9727681 SPAP_1667 Streptococcus pneumoniae AP200 hypothetical protein YP_003877253.1 1571555 R 574093 CDS YP_003877254.1 307068288 9727682 complement(1572337..1572600) 1 NC_014494.1 Operon 760 Gene 3 COG0762 Predicted integral membrane protein; putative integral membrane protein 1572600 9727682 SPAP_1668 Streptococcus pneumoniae AP200 putative integral membrane protein YP_003877254.1 1572337 R 574093 CDS YP_003877255.1 307068289 9727683 complement(1572600..1573139) 1 NC_014494.1 Operon 760 Gene 4 COG1799 Uncharacterized protein conserved in bacteria; hypothetical protein 1573139 9727683 SPAP_1669 Streptococcus pneumoniae AP200 hypothetical protein YP_003877255.1 1572600 R 574093 CDS YP_003877256.1 307068290 9727684 complement(1573149..1573820) 1 NC_014494.1 Operon 760 Gene 5 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 1573820 9727684 SPAP_1670 Streptococcus pneumoniae AP200 hypothetical protein YP_003877256.1 1573149 R 574093 CDS YP_003877257.1 307068291 9727685 complement(1573825..1575084) 1 NC_014494.1 Operon 760 Gene 6 COG0206 Cell division GTPase; cell division GTPase 1575084 9727685 SPAP_1671 Streptococcus pneumoniae AP200 cell division GTPase YP_003877257.1 1573825 R 574093 CDS YP_003877258.1 307068292 9727686 complement(1575101..1576474) 1 NC_014494.1 Operon 760 Gene 7 COG0849 Actin-like ATPase involved in cell division; actin-like ATPase 1576474 9727686 SPAP_1672 Streptococcus pneumoniae AP200 actin-like ATPase YP_003877258.1 1575101 R 574093 CDS YP_003877259.1 307068293 9727687 complement(1576693..1577397) 1 NC_014494.1 Operon 761 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1577397 9727687 SPAP_1673 Streptococcus pneumoniae AP200 hypothetical protein YP_003877259.1 1576693 R 574093 CDS YP_003877260.1 307068294 9727688 complement(1577488..1578099) 1 NC_014494.1 Operon 761 Gene 2 COG1051 ADP-ribose pyrophosphatase; ADP-ribose pyrophosphatase 1578099 9727688 SPAP_1674 Streptococcus pneumoniae AP200 ADP-ribose pyrophosphatase YP_003877260.1 1577488 R 574093 CDS YP_003877261.1 307068295 9727689 complement(1578086..1579459) 1 NC_014494.1 Operon 761 Gene 3 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramyl pentapeptide synthase 1579459 9727689 SPAP_1675 Streptococcus pneumoniae AP200 UDP-N-acetylmuramyl pentapeptide synthase YP_003877261.1 1578086 R 574093 CDS YP_003877262.1 307068296 9727690 complement(1579543..1580586) 1 NC_014494.1 Operon 761 Gene 4 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine-D-alanine ligase-like ATP-grasp enzyme 1580586 9727690 SPAP_1676 Streptococcus pneumoniae AP200 D-alanine-D-alanine ligase-like ATP-grasp enzyme YP_003877262.1 1579543 R 574093 CDS YP_003877263.1 307068297 9727691 complement(1580762..1581358) 1 NC_014494.1 Operon 762 Gene 1 COG0353 Recombinational DNA repair protein (RecF pathway); recombinational DNA repair ATPase 1581358 9727691 SPAP_1677 Streptococcus pneumoniae AP200 recombinational DNA repair ATPase YP_003877263.1 1580762 R 574093 CDS YP_003877264.1 307068298 9727692 complement(1581369..1583411) 1 NC_014494.1 Operon 762 Gene 2 COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein FtsI 1583411 9727692 SPAP_1678 Streptococcus pneumoniae AP200 cell division protein FtsI YP_003877264.1 1581369 R 574093 CDS YP_003877265.1 307068299 9727693 1583626..1584477 1 NC_014494.1 Operon 763 Gene 1 COG1737 Transcriptional regulators; transcriptional regulator 1584477 9727693 SPAP_1679 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877265.1 1583626 D 574093 CDS YP_003877266.1 307068300 9727694 complement(1584493..1585377) 1 NC_014494.1 Operon 764 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1585377 9727694 SPAP_1680 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003877266.1 1584493 R 574093 CDS YP_003877267.1 307068301 9727695 complement(1585395..1586312) 1 NC_014494.1 Operon 764 Gene 2 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase 1586312 9727695 SPAP_1681 Streptococcus pneumoniae AP200 dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_003877267.1 1585395 R 574093 CDS YP_003877268.1 307068302 9727696 complement(1586481..1587125) 1 NC_014494.1 Operon 765 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1587125 9727696 SPAP_1682 Streptococcus pneumoniae AP200 hypothetical protein YP_003877268.1 1586481 R 574093 CDS YP_003877269.1 307068303 9727697 complement(1587208..1587402) 1 NC_014494.1 Operon 765 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1587402 9727697 SPAP_1683 Streptococcus pneumoniae AP200 hypothetical protein YP_003877269.1 1587208 R 574093 CDS YP_003877270.1 307068304 9727698 complement(1587412..1587756) 1 NC_014494.1 Operon 765 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1587756 9727698 SPAP_1684 Streptococcus pneumoniae AP200 hypothetical protein YP_003877270.1 1587412 R 574093 CDS YP_003877271.1 307068305 9727699 complement(1587853..1588305) 1 NC_014494.1 Operon 765 Gene 4 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta 1588305 9727699 SPAP_1685 Streptococcus pneumoniae AP200 beta-galactosidase subunit beta YP_003877271.1 1587853 R 574093 CDS YP_003877272.1 307068306 9727700 complement(1588578..1589417) 1 NC_014494.1 Operon 766 Gene 1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 1589417 9727700 SPAP_1686 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877272.1 1588578 R 574093 CDS YP_003877273.1 307068307 9727701 complement(1589433..1590320) 1 NC_014494.1 Operon 766 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1590320 9727701 SPAP_1687 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877273.1 1589433 R 574093 CDS YP_003877274.1 307068308 9727702 complement(1590551..1591879) 1 NC_014494.1 Operon 766 Gene 3 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 1591879 9727702 SPAP_1688 Streptococcus pneumoniae AP200 sugar ABC transporter periplasmic protein YP_003877274.1 1590551 R 574093 CDS YP_003877275.1 307068309 9727703 complement(1592004..1593521) 1 NC_014494.1 Operon 767 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 1593521 9727703 SPAP_1689 Streptococcus pneumoniae AP200 PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC YP_003877275.1 1592004 R 574093 CDS YP_003877276.1 307068310 9727704 complement(1593540..1594238) 1 NC_014494.1 Operon 767 Gene 2 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; putative N-acetylmannosamine-6-phosphate epimerase 1594238 9727704 SPAP_1690 Streptococcus pneumoniae AP200 putative N-acetylmannosamine-6-phosphate epimerase YP_003877276.1 1593540 R 574093 CDS YP_003877277.1 307068311 9727705 complement(1594412..1595515) 1 NC_014494.1 Operon 768 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein 1595515 9727705 SPAP_1691 Streptococcus pneumoniae AP200 putative dehydrogenases-like protein YP_003877277.1 1594412 R 574093 CDS YP_003877278.1 307068312 9727706 complement(1595527..1597146) 1 NC_014494.1 neuraminidase NanB 1597146 9727706 SPAP_1692 Streptococcus pneumoniae AP200 neuraminidase NanB YP_003877278.1 1595527 R 574093 CDS YP_003877279.1 307068313 9727707 1597188..1597613 1 NC_014494.1 transposase-like protein, IS1515 1597613 9727707 SPAP_1693 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877279.1 1597188 D 574093 CDS YP_003877280.1 307068314 9727708 1597659..1598003 1 NC_014494.1 transposase-like protein, IS1515 1598003 9727708 SPAP_1694 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877280.1 1597659 D 574093 CDS YP_003877281.1 307068315 9727709 complement(1598000..1598494) 1 NC_014494.1 neuraminidase NanB 1598494 9727709 SPAP_1695 Streptococcus pneumoniae AP200 neuraminidase NanB YP_003877281.1 1598000 R 574093 CDS YP_003877282.1 307068316 9727710 complement(1598512..1599345) 1 NC_014494.1 Operon 770 Gene 2 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 1599345 9727710 SPAP_1696 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877282.1 1598512 R 574093 CDS YP_003877283.1 307068317 9727711 complement(1599345..1600229) 1 NC_014494.1 Operon 770 Gene 3 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1600229 9727711 SPAP_1697 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877283.1 1599345 R 574093 CDS YP_003877284.1 307068318 9727712 complement(1600308..1601645) 1 NC_014494.1 Operon 770 Gene 4 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 1601645 9727712 SPAP_1698 Streptococcus pneumoniae AP200 sugar ABC transporter periplasmic protein YP_003877284.1 1600308 R 574093 CDS YP_003877285.1 307068319 9727713 complement(1601664..1602116) 1 NC_014494.1 Operon 770 Gene 5 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta 1602116 9727713 SPAP_1699 Streptococcus pneumoniae AP200 beta-galactosidase subunit beta YP_003877285.1 1601664 R 574093 CDS YP_003877286.1 307068320 9727714 complement(1603130..1606027) 1 NC_014494.1 Operon 771 Gene 1 COG4409 Neuraminidase (sialidase); neuraminidase 1606027 9727714 SPAP_1700 Streptococcus pneumoniae AP200 neuraminidase YP_003877286.1 1603130 R 574093 CDS YP_003877287.1 307068321 9727715 complement(1606315..1606542) 1 NC_014494.1 Operon 771 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1606542 9727715 SPAP_1701 Streptococcus pneumoniae AP200 hypothetical protein YP_003877287.1 1606315 R 574093 CDS YP_003877288.1 307068322 9727716 1606940..1607443 1 NC_014494.1 Operon 772 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1607443 9727716 SPAP_1702 Streptococcus pneumoniae AP200 hypothetical protein YP_003877288.1 1606940 D 574093 CDS YP_003877289.1 307068323 9727717 complement(1607797..1608777) 1 NC_014494.1 Operon 773 Gene 1 COG3458 Acetyl esterase (deacetylase); acetyl esterase 1608777 9727717 SPAP_1703 Streptococcus pneumoniae AP200 acetyl esterase YP_003877289.1 1607797 R 574093 CDS YP_003877290.1 307068324 9727718 complement(1609093..1611108) 1 NC_014494.1 Operon 774 Gene 1 COG1200 RecG-like helicase; RecG-like helicase 1611108 9727718 SPAP_1704 Streptococcus pneumoniae AP200 RecG-like helicase YP_003877290.1 1609093 R 574093 CDS YP_003877291.1 307068325 9727719 complement(1611127..1612230) 1 NC_014494.1 Operon 774 Gene 2 COG0787 Alanine racemase; alanine racemase 1612230 9727719 SPAP_1705 Streptococcus pneumoniae AP200 alanine racemase YP_003877291.1 1611127 R 574093 CDS YP_003877292.1 307068326 9727720 complement(1612220..1612588) 1 NC_014494.1 Operon 774 Gene 3 COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); phosphopantetheinyl transferase 1612588 9727720 SPAP_1706 Streptococcus pneumoniae AP200 phosphopantetheinyl transferase YP_003877292.1 1612220 R 574093 CDS YP_003877293.1 307068327 9727721 complement(1612627..1613658) 1 NC_014494.1 Operon 774 Gene 4 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase 1613658 9727721 SPAP_1707 Streptococcus pneumoniae AP200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase YP_003877293.1 1612627 R 574093 CDS YP_003877294.1 307068328 9727722 complement(1613660..1614691) 1 NC_014494.1 Operon 774 Gene 5 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase 1614691 9727722 SPAP_1708 Streptococcus pneumoniae AP200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase YP_003877294.1 1613660 R 574093 CDS YP_003877295.1 307068329 9727723 complement(1614772..1617285) 1 NC_014494.1 Operon 774 Gene 6 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA 1617285 9727723 SPAP_1709 Streptococcus pneumoniae AP200 preprotein translocase subunit SecA YP_003877295.1 1614772 R 574093 CDS YP_003877296.1 307068330 9727724 complement(1617746..1618378) 1 NC_014494.1 Operon 775 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1618378 9727724 SPAP_1710 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003877296.1 1617746 R 574093 CDS YP_003877297.1 307068331 9727725 complement(1618382..1618957) 1 NC_014494.1 Operon 775 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1618957 9727725 SPAP_1711 Streptococcus pneumoniae AP200 hypothetical protein YP_003877297.1 1618382 R 574093 CDS YP_003877298.1 307068332 9727726 complement(1619016..1619807) 1 NC_014494.1 Operon 775 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1619807 9727726 SPAP_1712 Streptococcus pneumoniae AP200 hypothetical protein YP_003877298.1 1619016 R 574093 CDS YP_003877299.1 307068333 9727727 complement(1619992..1620327) 1 NC_014494.1 Operon 776 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1620327 9727727 SPAP_1713 Streptococcus pneumoniae AP200 hypothetical protein YP_003877299.1 1619992 R 574093 CDS YP_003877300.1 307068334 9727728 complement(1620893..1622203) 1 NC_014494.1 Operon 777 Gene 1 COG1160 Predicted GTPases; putative GTPase 1622203 9727728 SPAP_1714 Streptococcus pneumoniae AP200 putative GTPase YP_003877300.1 1620893 R 574093 CDS YP_003877301.1 307068335 9727729 complement(1622217..1622930) 1 NC_014494.1 Operon 777 Gene 2 COG0778 Nitroreductase; nitroreductase 1622930 9727729 SPAP_1715 Streptococcus pneumoniae AP200 nitroreductase YP_003877301.1 1622217 R 574093 CDS YP_003877302.1 307068336 9727730 complement(1622927..1623823) 1 NC_014494.1 Operon 777 Gene 3 COG1484 DNA replication protein; DNA replication protein 1623823 9727730 SPAP_1716 Streptococcus pneumoniae AP200 DNA replication protein YP_003877302.1 1622927 R 574093 CDS YP_003877303.1 307068337 9727731 complement(1623824..1624993) 1 NC_014494.1 Operon 777 Gene 4 COG3611 Replication initiation/membrane attachment protein; Replication initiation/membrane attachment protein 1624993 9727731 SPAP_1717 Streptococcus pneumoniae AP200 Replication initiation/membrane attachment protein YP_003877303.1 1623824 R 574093 CDS YP_003877304.1 307068338 9727732 complement(1624994..1625467) 1 NC_014494.1 Operon 777 Gene 5 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; putative transcriptional regulator 1625467 9727732 SPAP_1718 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877304.1 1624994 R 574093 CDS YP_003877305.1 307068339 9727733 1625607..1625972 1 NC_014494.1 Operon 778 Gene 1 COG1725 Predicted transcriptional regulators; putative transcriptional regulator 1625972 9727733 SPAP_1719 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877305.1 1625607 D 574093 CDS YP_003877306.1 307068340 9727734 1625977..1626672 1 NC_014494.1 Operon 778 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1626672 9727734 SPAP_1720 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003877306.1 1625977 D 574093 CDS YP_003877307.1 307068341 9727735 1626689..1627456 1 NC_014494.1 Operon 778 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1627456 9727735 SPAP_1721 Streptococcus pneumoniae AP200 hypothetical protein YP_003877307.1 1626689 D 574093 CDS YP_003877308.1 307068342 9727736 complement(1627809..1629008) 1 NC_014494.1 Operon 779 Gene 1 COG1668 ABC-type Na+ efflux pump, permease component; Na+ efflux pump ABC transporter permease 1629008 9727736 SPAP_1722 Streptococcus pneumoniae AP200 Na+ efflux pump ABC transporter permease YP_003877308.1 1627809 R 574093 CDS YP_003877309.1 307068343 9727737 complement(1629005..1629898) 1 NC_014494.1 Operon 779 Gene 2 COG4152 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase 1629898 9727737 SPAP_1723 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003877309.1 1629005 R 574093 CDS YP_003877310.1 307068344 9727738 1630590..1630793 1 NC_014494.1 transposase-like protein, IS1239 1630793 9727738 SPAP_1724 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877310.1 1630590 D 574093 CDS YP_003877311.1 307068345 9727739 1631208..1631825 1 NC_014494.1 Operon 781 Gene 1 COG0398 Uncharacterized conserved protein; hypothetical protein 1631825 9727739 SPAP_1725 Streptococcus pneumoniae AP200 hypothetical protein YP_003877311.1 1631208 D 574093 CDS YP_003877312.1 307068346 9727740 complement(1632145..1633032) 1 NC_014494.1 Operon 782 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1633032 9727740 SPAP_1726 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003877312.1 1632145 R 574093 CDS YP_003877313.1 307068347 9727741 complement(1633181..1635118) 1 NC_014494.1 Operon 783 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 1635118 9727741 SPAP_1727 Streptococcus pneumoniae AP200 PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC YP_003877313.1 1633181 R 574093 CDS YP_003877314.1 307068348 9727742 complement(1635244..1635441) 1 NC_014494.1 Operon 784 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1635441 9727742 SPAP_1728 Streptococcus pneumoniae AP200 hypothetical protein YP_003877314.1 1635244 R 574093 CDS YP_003877315.1 307068349 9727743 1635494..1636948 1 NC_014494.1 Operon 785 Gene 1 COG1621 Beta-fructosidases (levanase/invertase); levanase/invertase 1636948 9727743 SPAP_1729 Streptococcus pneumoniae AP200 levanase/invertase YP_003877315.1 1635494 D 574093 CDS YP_003877316.1 307068350 9727744 1636929..1637894 1 NC_014494.1 Operon 785 Gene 2 COG1609 Transcriptional regulators; transcriptional regulator 1637894 9727744 SPAP_1730 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877316.1 1636929 D 574093 CDS YP_003877317.1 307068351 9727745 complement(1637929..1639203) 1 NC_014494.1 Operon 786 Gene 1 COG1257 Hydroxymethylglutaryl-CoA reductase; hydroxymethylglutaryl-CoA reductase 1639203 9727745 SPAP_1731 Streptococcus pneumoniae AP200 hydroxymethylglutaryl-CoA reductase YP_003877317.1 1637929 R 574093 CDS YP_003877318.1 307068352 9727746 complement(1639203..1640399) 1 NC_014494.1 Operon 786 Gene 2 COG3425 3-hydroxy-3-methylglutaryl CoA synthase; 3-hydroxy-3-methylglutaryl CoA synthase 1640399 9727746 SPAP_1732 Streptococcus pneumoniae AP200 3-hydroxy-3-methylglutaryl CoA synthase YP_003877318.1 1639203 R 574093 CDS YP_003877319.1 307068353 9727747 complement(1640506..1640793) 1 NC_014494.1 Operon 787 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1640793 9727747 SPAP_1733 Streptococcus pneumoniae AP200 hypothetical protein YP_003877319.1 1640506 R 574093 CDS YP_003877320.1 307068354 9727748 complement(1640822..1641121) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1641121 9727748 SPAP_1734 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003877320.1 1640822 R 574093 CDS YP_003877321.1 307068355 9727749 complement(1641509..1641958) 1 NC_014494.1 Operon 788 Gene 1 COG3610 Uncharacterized conserved protein; hypothetical protein 1641958 9727749 SPAP_1735 Streptococcus pneumoniae AP200 hypothetical protein YP_003877321.1 1641509 R 574093 CDS YP_003877322.1 307068356 9727750 complement(1641960..1642718) 1 NC_014494.1 Operon 788 Gene 2 COG2966 Uncharacterized conserved protein; hypothetical protein 1642718 9727750 SPAP_1736 Streptococcus pneumoniae AP200 hypothetical protein YP_003877322.1 1641960 R 574093 CDS YP_003877323.1 307068357 9727751 complement(1642833..1644812) 1 NC_014494.1 Operon 789 Gene 1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 1644812 9727751 SPAP_1737 Streptococcus pneumoniae AP200 serine/threonine protein kinase YP_003877323.1 1642833 R 574093 CDS YP_003877324.1 307068358 9727752 complement(1644809..1645549) 1 NC_014494.1 Operon 789 Gene 2 COG0631 Serine/threonine protein phosphatase; serine/threonine protein phosphatase 1645549 9727752 SPAP_1738 Streptococcus pneumoniae AP200 serine/threonine protein phosphatase YP_003877324.1 1644809 R 574093 CDS YP_003877325.1 307068359 9727753 complement(1645564..1646877) 1 NC_014494.1 Operon 789 Gene 3 COG0144 tRNA and rRNA cytosine-C5-methylases; tRNA and rRNA cytosine-C5-methylase 1646877 9727753 SPAP_1739 Streptococcus pneumoniae AP200 tRNA and rRNA cytosine-C5-methylase YP_003877325.1 1645564 R 574093 CDS YP_003877326.1 307068360 9727754 complement(1646870..1647805) 1 NC_014494.1 Operon 789 Gene 4 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 1647805 9727754 SPAP_1740 Streptococcus pneumoniae AP200 methionyl-tRNA formyltransferase YP_003877326.1 1646870 R 574093 CDS YP_003877327.1 307068361 9727755 complement(1647818..1650214) 1 NC_014494.1 Operon 789 Gene 5 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosomal protein N' 1650214 9727755 SPAP_1741 Streptococcus pneumoniae AP200 primosomal protein N' YP_003877327.1 1647818 R 574093 CDS YP_003877328.1 307068362 9727756 complement(1650280..1650594) 1 NC_014494.1 Operon 789 Gene 6 COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit K/omega 1650594 9727756 SPAP_1742 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase subunit K/omega YP_003877328.1 1650280 R 574093 CDS YP_003877329.1 307068363 9727757 complement(1650619..1651245) 1 NC_014494.1 Operon 789 Gene 7 COG0194 Guanylate kinase; guanylate kinase 1651245 9727757 SPAP_1743 Streptococcus pneumoniae AP200 guanylate kinase YP_003877329.1 1650619 R 574093 CDS YP_003877330.1 307068364 9727758 complement(1651375..1652988) 1 NC_014494.1 Operon 790 Gene 1 COG1418 Predicted HD superfamily hydrolase; putative HD superfamily hydrolase 1652988 9727758 SPAP_1744 Streptococcus pneumoniae AP200 putative HD superfamily hydrolase YP_003877330.1 1651375 R 574093 CDS YP_003877331.1 307068365 9727759 1652933..1653076 1 NC_014494.1 Operon 791 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1653076 9727759 SPAP_1745 Streptococcus pneumoniae AP200 hypothetical protein YP_003877331.1 1652933 D 574093 CDS YP_003877332.1 307068366 9727760 complement(1653179..1653433) 1 NC_014494.1 Operon 792 Gene 1 COG4115 Uncharacterized protein conserved in bacteria; hypothetical protein 1653433 9727760 SPAP_1746 Streptococcus pneumoniae AP200 hypothetical protein YP_003877332.1 1653179 R 574093 CDS YP_003877333.1 307068367 9727761 complement(1653437..1653691) 1 NC_014494.1 Operon 792 Gene 2 COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin of toxin-antitoxin stability system 1653691 9727761 SPAP_1747 Streptococcus pneumoniae AP200 antitoxin of toxin-antitoxin stability system YP_003877333.1 1653437 R 574093 CDS YP_003877334.1 307068368 9727762 complement(1653929..1655026) 1 NC_014494.1 Operon 793 Gene 1 COG1323 Predicted nucleotidyltransferase; putative nucleotidyltransferase 1655026 9727762 SPAP_1748 Streptococcus pneumoniae AP200 putative nucleotidyltransferase YP_003877334.1 1653929 R 574093 CDS YP_003877335.1 307068369 9727763 complement(1655036..1655782) 1 NC_014494.1 Operon 793 Gene 2 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 1655782 9727763 SPAP_1749 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003877335.1 1655036 R 574093 CDS YP_003877336.1 307068370 9727764 complement(1655885..1656238) 1 NC_014494.1 Operon 794 Gene 1 COG0799 Uncharacterized homolog of plant Iojap protein; plant Iojap-like protein 1656238 9727764 SPAP_1750 Streptococcus pneumoniae AP200 plant Iojap-like protein YP_003877336.1 1655885 R 574093 CDS YP_003877337.1 307068371 9727765 complement(1656251..1656751) 1 NC_014494.1 Operon 794 Gene 2 COG1335 Amidases related to nicotinamidase; amidase 1656751 9727765 SPAP_1751 Streptococcus pneumoniae AP200 amidase YP_003877337.1 1656251 R 574093 CDS YP_003877338.1 307068372 9727766 complement(1656752..1657345) 1 NC_014494.1 Operon 794 Gene 3 COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism; putative HD superfamily hydrolase 1657345 9727766 SPAP_1752 Streptococcus pneumoniae AP200 putative HD superfamily hydrolase YP_003877338.1 1656752 R 574093 CDS YP_003877339.1 307068373 9727767 complement(1657345..1657974) 1 NC_014494.1 Operon 794 Gene 4 COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinic acid mononucleotide adenylyltransferase 1657974 9727767 SPAP_1753 Streptococcus pneumoniae AP200 nicotinic acid mononucleotide adenylyltransferase YP_003877339.1 1657345 R 574093 CDS YP_003877340.1 307068374 9727768 complement(1658026..1658337) 1 NC_014494.1 Operon 794 Gene 5 protein supported gi|15901580|ref|NP_346184.1| hypothetical protein SP_1748; hypothetical protein 1658337 9727768 SPAP_1754 Streptococcus pneumoniae AP200 hypothetical protein YP_003877340.1 1658026 R 574093 CDS YP_003877341.1 307068375 9727769 complement(1658552..1659658) 1 NC_014494.1 Operon 795 Gene 1 COG1161 Predicted GTPases; putative GTPase 1659658 9727769 SPAP_1755 Streptococcus pneumoniae AP200 putative GTPase YP_003877341.1 1658552 R 574093 CDS YP_003877342.1 307068376 9727770 complement(1659661..1660188) 1 NC_014494.1 Operon 795 Gene 2 COG2179 Predicted hydrolase of the HAD superfamily; putative HAD superfamily hydrolase 1660188 9727770 SPAP_1756 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003877342.1 1659661 R 574093 CDS YP_003877343.1 307068377 9727771 complement(1660203..1661111) 1 NC_014494.1 Operon 795 Gene 3 COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter 1661111 9727771 SPAP_1757 Streptococcus pneumoniae AP200 Mg2+ and Co2+ transporter YP_003877343.1 1660203 R 574093 CDS YP_003877344.1 307068378 9727772 complement(1661168..1661728) 1 NC_014494.1 Operon 795 Gene 4 COG0668 Small-conductance mechanosensitive channel; small-conductance mechanosensitive channel 1661728 9727772 SPAP_1758 Streptococcus pneumoniae AP200 small-conductance mechanosensitive channel YP_003877344.1 1661168 R 574093 CDS YP_003877345.1 307068379 9727773 1661932..1662120 1 NC_014494.1 Operon 796 Gene 1 COG3633 Na+/serine symporter; Na+/serine symporter 1662120 9727773 SPAP_1759 Streptococcus pneumoniae AP200 Na+/serine symporter YP_003877345.1 1661932 D 574093 CDS YP_003877346.1 307068380 9727774 1662117..1663085 1 NC_014494.1 Operon 796 Gene 2 COG3633 Na+/serine symporter; Na+/serine symporter 1663085 9727774 SPAP_1760 Streptococcus pneumoniae AP200 Na+/serine symporter YP_003877346.1 1662117 D 574093 CDS YP_003877347.1 307068381 9727775 1663153..1664106 1 NC_014494.1 Operon 796 Gene 3 COG4129 Predicted membrane protein; hypothetical protein 1664106 9727775 SPAP_1761 Streptococcus pneumoniae AP200 hypothetical protein YP_003877347.1 1663153 D 574093 CDS YP_003877348.1 307068382 9727776 1664250..1664630 1 NC_014494.1 Operon 797 Gene 1 COG1846 Transcriptional regulators; transcriptional regulator 1664630 9727776 SPAP_1762 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877348.1 1664250 D 574093 CDS YP_003877349.1 307068383 9727777 1664730..1664951 1 NC_014494.1 Operon 798 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1664951 9727777 SPAP_1763 Streptococcus pneumoniae AP200 hypothetical protein YP_003877349.1 1664730 D 574093 CDS YP_003877350.1 307068384 9727778 1664968..1665282 1 NC_014494.1 Operon 798 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 1665282 9727778 SPAP_1764 Streptococcus pneumoniae AP200 thiol-disulfide isomerase and thioredoxin YP_003877350.1 1664968 D 574093 CDS YP_003877351.1 307068385 9727779 1665588..1666121 1 NC_014494.1 Operon 799 Gene 1 protein supported gi|148994988|ref|ZP_01823966.1| ribosomal protein L11 methyltransferase; hypothetical protein 1666121 9727779 SPAP_1765 Streptococcus pneumoniae AP200 hypothetical protein YP_003877351.1 1665588 D 574093 CDS YP_003877352.1 307068386 9727780 complement(1666331..1666999) 1 NC_014494.1 Operon 800 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease 1666999 9727780 SPAP_1766 Streptococcus pneumoniae AP200 glycerol uptake facilitator-like permease YP_003877352.1 1666331 R 574093 CDS YP_003877353.1 307068387 9727781 complement(1667110..1667901) 1 NC_014494.1 Operon 800 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1667901 9727781 SPAP_1767 Streptococcus pneumoniae AP200 hypothetical protein YP_003877353.1 1667110 R 574093 CDS YP_003877354.1 307068388 9727782 complement(1668326..1669090) 1 NC_014494.1 Operon 801 Gene 1 COG0842 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease 1669090 9727782 SPAP_1768 Streptococcus pneumoniae AP200 multidrug ABC transporter permease YP_003877354.1 1668326 R 574093 CDS YP_003877355.1 307068389 9727783 complement(1669083..1669853) 1 NC_014494.1 Operon 801 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1669853 9727783 SPAP_1769 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003877355.1 1669083 R 574093 CDS YP_003877356.1 307068390 9727784 1670102..1670779 1 NC_014494.1 Operon 802 Gene 1 COG0640 Predicted transcriptional regulators; putative transcriptional regulator 1670779 9727784 SPAP_1770 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877356.1 1670102 D 574093 CDS YP_003877357.1 307068391 9727785 complement(1670839..1672635) 1 NC_014494.1 Operon 803 Gene 1 COG1164 Oligoendopeptidase F; oligoendopeptidase F 1672635 9727785 SPAP_1771 Streptococcus pneumoniae AP200 oligoendopeptidase F YP_003877357.1 1670839 R 574093 CDS YP_003877358.1 307068392 9727786 complement(1672646..1673389) 1 NC_014494.1 Operon 803 Gene 2 COG1385 Uncharacterized protein conserved in bacteria; hypothetical protein 1673389 9727786 SPAP_1772 Streptococcus pneumoniae AP200 hypothetical protein YP_003877358.1 1672646 R 574093 CDS YP_003877359.1 307068393 9727787 complement(1673391..1674341) 1 NC_014494.1 Operon 803 Gene 3 protein supported gi|148997825|ref|ZP_01825389.1| ribosomal protein L11 methyltransferase; hypothetical protein 1674341 9727787 SPAP_1773 Streptococcus pneumoniae AP200 hypothetical protein YP_003877359.1 1673391 R 574093 CDS YP_003877360.1 307068394 9727788 complement(1674477..1674905) 1 NC_014494.1 Operon 804 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 1674905 9727788 SPAP_1774 Streptococcus pneumoniae AP200 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_003877360.1 1674477 R 574093 CDS YP_003877361.1 307068395 9727789 complement(1674886..1675974) 1 NC_014494.1 Operon 804 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1675974 9727789 SPAP_1775 Streptococcus pneumoniae AP200 hypothetical protein YP_003877361.1 1674886 R 574093 CDS YP_003877362.1 307068396 9727790 complement(1675993..1676463) 1 NC_014494.1 Operon 804 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1676463 9727790 SPAP_1776 Streptococcus pneumoniae AP200 hypothetical protein YP_003877362.1 1675993 R 574093 CDS YP_003877363.1 307068397 9727791 complement(1676754..1677206) 1 NC_014494.1 Operon 805 Gene 1 COG1598 Uncharacterized conserved protein; hypothetical protein 1677206 9727791 SPAP_1777 Streptococcus pneumoniae AP200 hypothetical protein YP_003877363.1 1676754 R 574093 CDS YP_003877364.1 307068398 9727792 complement(1677243..1677422) 1 NC_014494.1 Operon 805 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1677422 9727792 SPAP_1778 Streptococcus pneumoniae AP200 hypothetical protein YP_003877364.1 1677243 R 574093 CDS YP_003877365.1 307068399 9727793 complement(1677559..1677666) 1 NC_014494.1 Operon 806 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1677666 9727793 SPAP_1779 Streptococcus pneumoniae AP200 hypothetical protein YP_003877365.1 1677559 R 574093 CDS YP_003877366.1 307068400 9727794 complement(1677903..1678124) 1 NC_014494.1 Operon 807 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1678124 9727794 SPAP_1780 Streptococcus pneumoniae AP200 hypothetical protein YP_003877366.1 1677903 R 574093 CDS YP_003877367.1 307068401 9727795 1678416..1679687 1 NC_014494.1 Operon 808 Gene 1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; ATPase 1679687 9727795 SPAP_1781 Streptococcus pneumoniae AP200 ATPase YP_003877367.1 1678416 D 574093 CDS YP_003877368.1 307068402 9727797 complement(1680232..1681551) 1 NC_014494.1 Operon 809 Gene 1 COG1621 Beta-fructosidases (levanase/invertase); levanase/invertase 1681551 9727797 SPAP_1783 Streptococcus pneumoniae AP200 levanase/invertase YP_003877368.1 1680232 R 574093 CDS YP_003877369.1 307068403 9727798 complement(1681561..1683177) 1 NC_014494.1 Operon 809 Gene 2 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 1683177 9727798 SPAP_1784 Streptococcus pneumoniae AP200 sugar ABC transporter periplasmic protein YP_003877369.1 1681561 R 574093 CDS YP_003877370.1 307068404 9727799 complement(1683206..1684096) 1 NC_014494.1 Operon 809 Gene 3 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 1684096 9727799 SPAP_1785 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877370.1 1683206 R 574093 CDS YP_003877371.1 307068405 9727800 complement(1684107..1685024) 1 NC_014494.1 Operon 809 Gene 4 COG4209 ABC-type polysaccharide transport system, permease component; polysaccharide ABC transporter permease 1685024 9727800 SPAP_1786 Streptococcus pneumoniae AP200 polysaccharide ABC transporter permease YP_003877371.1 1684107 R 574093 CDS YP_003877372.1 307068406 9727801 complement(1685174..1686175) 1 NC_014494.1 Operon 810 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator 1686175 9727801 SPAP_1787 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877372.1 1685174 R 574093 CDS YP_003877373.1 307068407 9727802 complement(1686536..1688017) 1 NC_014494.1 Operon 811 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1688017 9727802 SPAP_1788 Streptococcus pneumoniae AP200 hypothetical protein YP_003877373.1 1686536 R 574093 CDS YP_003877374.1 307068408 9727803 1688460..1688624 1 NC_014494.1 Operon 812 Gene 1 COG2261 Predicted membrane protein; hypothetical protein 1688624 9727803 SPAP_1789 Streptococcus pneumoniae AP200 hypothetical protein YP_003877374.1 1688460 D 574093 CDS YP_003877375.1 307068409 9727804 1688708..1689274 1 NC_014494.1 Operon 812 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1689274 9727804 SPAP_1790 Streptococcus pneumoniae AP200 hypothetical protein YP_003877375.1 1688708 D 574093 CDS YP_003877376.1 307068410 9727805 1689286..1689456 1 NC_014494.1 Operon 812 Gene 3 COG5547 Small integral membrane protein; small integral membrane protein 1689456 9727805 SPAP_1791 Streptococcus pneumoniae AP200 small integral membrane protein YP_003877376.1 1689286 D 574093 CDS YP_003877377.1 307068411 9727806 1689495..1690103 1 NC_014494.1 Operon 812 Gene 4 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein 1690103 9727806 SPAP_1792 Streptococcus pneumoniae AP200 hypothetical protein YP_003877377.1 1689495 D 574093 CDS YP_003877378.1 307068412 9727807 1690134..1690337 1 NC_014494.1 Operon 812 Gene 5 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein 1690337 9727807 SPAP_1793 Streptococcus pneumoniae AP200 hypothetical protein YP_003877378.1 1690134 D 574093 CDS YP_003877379.1 307068413 9727808 complement(1690430..1690669) 1 NC_014494.1 Operon 813 Gene 1 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_5 1690669 9727808 SPAP_1794 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_5 YP_003877379.1 1690430 R 574093 CDS YP_003877380.1 307068414 9727809 1690948..1691193 1 NC_014494.1 Operon 814 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1691193 9727809 SPAP_1795 Streptococcus pneumoniae AP200 hypothetical protein YP_003877380.1 1690948 D 574093 CDS YP_003877381.1 307068415 9727810 complement(1691471..1691899) 1 NC_014494.1 Operon 815 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1691899 9727810 SPAP_1796 Streptococcus pneumoniae AP200 hypothetical protein YP_003877381.1 1691471 R 574093 CDS YP_003877382.1 307068416 9727811 complement(1692256..1693104) 1 NC_014494.1 Operon 816 Gene 1 COG1262 Uncharacterized conserved protein; hypothetical protein 1693104 9727811 SPAP_1797 Streptococcus pneumoniae AP200 hypothetical protein YP_003877382.1 1692256 R 574093 CDS YP_003877383.1 307068417 9727812 complement(1693101..1694576) 1 NC_014494.1 Operon 816 Gene 2 COG3119 Arylsulfatase A and related enzymes; arylsulfatase A-like enzyme 1694576 9727812 SPAP_1798 Streptococcus pneumoniae AP200 arylsulfatase A-like enzyme YP_003877383.1 1693101 R 574093 CDS YP_003877384.1 307068418 9727813 complement(1694900..1695397) 1 NC_014494.1 Operon 817 Gene 1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1695397 9727813 SPAP_1799 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003877384.1 1694900 R 574093 CDS YP_003877385.1 307068419 9727814 complement(1695339..1696256) 1 NC_014494.1 Operon 817 Gene 2 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1696256 9727814 SPAP_1800 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003877385.1 1695339 R 574093 CDS YP_003877386.1 307068420 9727815 complement(1696266..1696583) 1 NC_014494.1 Operon 817 Gene 3 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 1696583 9727815 SPAP_1801 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIA YP_003877386.1 1696266 R 574093 CDS YP_003877387.1 307068421 9727816 complement(1696600..1696917) 1 NC_014494.1 Operon 817 Gene 4 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 1696917 9727816 SPAP_1802 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIB YP_003877387.1 1696600 R 574093 CDS YP_003877388.1 307068422 9727817 complement(1696932..1697828) 1 NC_014494.1 Operon 817 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 1697828 9727817 SPAP_1803 Streptococcus pneumoniae AP200 hypothetical protein YP_003877388.1 1696932 R 574093 CDS YP_003877389.1 307068423 9727818 complement(1697831..1699093) 1 NC_014494.1 Operon 817 Gene 6 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1699093 9727818 SPAP_1804 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003877389.1 1697831 R 574093 CDS YP_003877390.1 307068424 9727819 1699373..1700551 1 NC_014494.1 Operon 818 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1700551 9727819 SPAP_1805 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003877390.1 1699373 D 574093 CDS YP_003877391.1 307068425 9727820 complement(1700779..1701225) 1 NC_014494.1 Operon 819 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 1701225 9727820 SPAP_1806 Streptococcus pneumoniae AP200 acetyltransferase YP_003877391.1 1700779 R 574093 CDS YP_003877392.1 307068426 9727821 1701295..1701954 1 NC_014494.1 Operon 820 Gene 1 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; type II secretory pathway, prepilin signal peptidase PulO-like peptidase 1701954 9727821 SPAP_1807 Streptococcus pneumoniae AP200 type II secretory pathway, prepilin signal peptidase PulO-like peptidase YP_003877392.1 1701295 D 574093 CDS YP_003877393.1 307068427 9727822 complement(1702006..1703157) 1 NC_014494.1 Operon 821 Gene 1 COG2856 Predicted Zn peptidase; putative Zn peptidase 1703157 9727822 SPAP_1808 Streptococcus pneumoniae AP200 putative Zn peptidase YP_003877393.1 1702006 R 574093 CDS YP_003877394.1 307068428 9727823 complement(1703172..1703903) 1 NC_014494.1 Operon 821 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1703903 9727823 SPAP_1809 Streptococcus pneumoniae AP200 hypothetical protein YP_003877394.1 1703172 R 574093 CDS YP_003877395.1 307068429 9727824 complement(1704205..1704981) 1 NC_014494.1 Operon 822 Gene 1 protein supported gi|148997862|ref|ZP_01825426.1| ribosomal protein L11 methyltransferase; hypothetical protein 1704981 9727824 SPAP_1810 Streptococcus pneumoniae AP200 hypothetical protein YP_003877395.1 1704205 R 574093 CDS YP_003877396.1 307068430 9727825 complement(1704974..1706197) 1 NC_014494.1 Operon 822 Gene 2 COG0133 Tryptophan synthase beta chain; tryptophan synthase beta chain 1706197 9727825 SPAP_1811 Streptococcus pneumoniae AP200 tryptophan synthase beta chain YP_003877396.1 1704974 R 574093 CDS YP_003877397.1 307068431 9727826 complement(1706175..1706774) 1 NC_014494.1 Operon 822 Gene 3 COG0135 Phosphoribosylanthranilate isomerase; phosphoribosylanthranilate isomerase 1706774 9727826 SPAP_1812 Streptococcus pneumoniae AP200 phosphoribosylanthranilate isomerase YP_003877397.1 1706175 R 574093 CDS YP_003877398.1 307068432 9727827 complement(1706761..1707528) 1 NC_014494.1 Operon 822 Gene 4 COG0134 Indole-3-glycerol phosphate synthase; indole-3-glycerol phosphate synthase 1707528 9727827 SPAP_1813 Streptococcus pneumoniae AP200 indole-3-glycerol phosphate synthase YP_003877398.1 1706761 R 574093 CDS YP_003877399.1 307068433 9727828 complement(1707525..1708529) 1 NC_014494.1 Operon 822 Gene 5 COG0547 Anthranilate phosphoribosyltransferase; anthranilate phosphoribosyltransferase 1708529 9727828 SPAP_1814 Streptococcus pneumoniae AP200 anthranilate phosphoribosyltransferase YP_003877399.1 1707525 R 574093 CDS YP_003877400.1 307068434 9727829 complement(1708540..1709106) 1 NC_014494.1 Operon 822 Gene 6 COG0512 Anthranilate/para-aminobenzoate synthases component II; anthranilate/para-aminobenzoate synthases component II 1709106 9727829 SPAP_1815 Streptococcus pneumoniae AP200 anthranilate/para-aminobenzoate synthases component II YP_003877400.1 1708540 R 574093 CDS YP_003877401.1 307068435 9727830 complement(1709103..1710464) 1 NC_014494.1 Operon 822 Gene 7 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate/para-aminobenzoate synthases component I 1710464 9727830 SPAP_1816 Streptococcus pneumoniae AP200 anthranilate/para-aminobenzoate synthases component I YP_003877401.1 1709103 R 574093 CDS YP_003877402.1 307068436 9727831 complement(1711605..1712606) 1 NC_014494.1 Operon 823 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator 1712606 9727831 SPAP_1817 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877402.1 1711605 R 574093 CDS YP_003877403.1 307068437 9727832 complement(1712714..1712905) 1 NC_014494.1 Operon 824 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1712905 9727832 SPAP_1818 Streptococcus pneumoniae AP200 hypothetical protein YP_003877403.1 1712714 R 574093 CDS YP_003877404.1 307068438 9727833 complement(1713178..1713888) 1 NC_014494.1 Operon 825 Gene 1 COG1285 Uncharacterized membrane protein; hypothetical protein 1713888 9727833 SPAP_1819 Streptococcus pneumoniae AP200 hypothetical protein YP_003877404.1 1713178 R 574093 CDS YP_003877405.1 307068439 9727834 complement(1713891..1715582) 1 NC_014494.1 Operon 825 Gene 2 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease 1715582 9727834 SPAP_1820 Streptococcus pneumoniae AP200 Fe3+ ABC transporter permease YP_003877405.1 1713891 R 574093 CDS YP_003877406.1 307068440 9727835 complement(1715594..1716604) 1 NC_014494.1 Operon 825 Gene 3 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase 1716604 9727835 SPAP_1821 Streptococcus pneumoniae AP200 spermidine/putrescine ABC transporter ATPase YP_003877406.1 1715594 R 574093 CDS YP_003877407.1 307068441 9727836 complement(1716708..1717775) 1 NC_014494.1 Operon 825 Gene 4 COG1840 ABC-type Fe3+ transport system, periplasmic component; Fe3+ ABC transporter periplasmic protein 1717775 9727836 SPAP_1822 Streptococcus pneumoniae AP200 Fe3+ ABC transporter periplasmic protein YP_003877407.1 1716708 R 574093 CDS YP_003877408.1 307068442 9727837 complement(1717800..1718459) 1 NC_014494.1 Operon 825 Gene 5 COG5255 Uncharacterized protein conserved in bacteria; hypothetical protein 1718459 9727837 SPAP_1823 Streptococcus pneumoniae AP200 hypothetical protein YP_003877408.1 1717800 R 574093 CDS YP_003877409.1 307068443 9727838 complement(1718639..1719649) 1 NC_014494.1 Operon 826 Gene 1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1719649 9727838 SPAP_1824 Streptococcus pneumoniae AP200 UDP-glucose 4-epimerase YP_003877409.1 1718639 R 574093 CDS YP_003877410.1 307068444 9727839 complement(1719662..1721137) 1 NC_014494.1 Operon 826 Gene 2 COG4468 Galactose-1-phosphate uridyltransferase; galactose-1-phosphate uridyltransferase 1721137 9727839 SPAP_1825 Streptococcus pneumoniae AP200 galactose-1-phosphate uridyltransferase YP_003877410.1 1719662 R 574093 CDS YP_003877411.1 307068445 9727840 complement(1721150..1721791) 1 NC_014494.1 Operon 826 Gene 3 COG0704 Phosphate uptake regulator; phosphate uptake regulator 1721791 9727840 SPAP_1826 Streptococcus pneumoniae AP200 phosphate uptake regulator YP_003877411.1 1721150 R 574093 CDS YP_003877412.1 307068446 9727841 complement(1721849..1722250) 1 NC_014494.1 Operon 826 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1722250 9727841 SPAP_1827 Streptococcus pneumoniae AP200 hypothetical protein YP_003877412.1 1721849 R 574093 CDS YP_003877413.1 307068447 9727842 complement(1722404..1722700) 1 NC_014494.1 Operon 827 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1722700 9727842 SPAP_1828 Streptococcus pneumoniae AP200 hypothetical protein YP_003877413.1 1722404 R 574093 CDS YP_003877414.1 307068448 9727843 complement(1722684..1724810) 1 NC_014494.1 Operon 827 Gene 2 COG5434 Endopolygalacturonase; endopolygalacturonase 1724810 9727843 SPAP_1829 Streptococcus pneumoniae AP200 endopolygalacturonase YP_003877414.1 1722684 R 574093 CDS YP_003877415.1 307068449 9727844 1725758..1725931 1 NC_014494.1 Operon 828 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1725931 9727844 SPAP_1830 Streptococcus pneumoniae AP200 hypothetical protein YP_003877415.1 1725758 D 574093 CDS YP_003877416.1 307068450 9727845 complement(1725973..1727199) 1 NC_014494.1 Operon 829 Gene 1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; hypothetical protein 1727199 9727845 SPAP_1831 Streptococcus pneumoniae AP200 hypothetical protein YP_003877416.1 1725973 R 574093 CDS YP_003877417.1 307068451 9727846 complement(1727242..1727934) 1 NC_014494.1 Operon 829 Gene 2 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; sugar transferase 1727934 9727846 SPAP_1832 Streptococcus pneumoniae AP200 sugar transferase YP_003877417.1 1727242 R 574093 CDS YP_003877418.1 307068452 9727847 complement(1728107..1729858) 1 NC_014494.1 Operon 830 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1729858 9727847 SPAP_1833 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877418.1 1728107 R 574093 CDS YP_003877419.1 307068453 9727848 complement(1729848..1731593) 1 NC_014494.1 Operon 830 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1731593 9727848 SPAP_1834 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877419.1 1729848 R 574093 CDS YP_003877420.1 307068454 9727849 complement(1731799..1732176) 1 NC_014494.1 Operon 831 Gene 1 COG2323 Predicted membrane protein; hypothetical protein 1732176 9727849 SPAP_1835 Streptococcus pneumoniae AP200 hypothetical protein YP_003877420.1 1731799 R 574093 CDS YP_003877421.1 307068455 9727850 complement(1732248..1732517) 1 NC_014494.1 Operon 831 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1732517 9727850 SPAP_1836 Streptococcus pneumoniae AP200 hypothetical protein YP_003877421.1 1732248 R 574093 CDS YP_003877422.1 307068456 9727851 complement(1732548..1732703) 1 NC_014494.1 Operon 831 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1732703 9727851 SPAP_1837 Streptococcus pneumoniae AP200 hypothetical protein YP_003877422.1 1732548 R 574093 CDS YP_003877423.1 307068457 9727852 1732837..1733664 1 NC_014494.1 Operon 832 Gene 1 COG0708 Exonuclease III; exonuclease III 1733664 9727852 SPAP_1838 Streptococcus pneumoniae AP200 exonuclease III YP_003877423.1 1732837 D 574093 CDS YP_003877424.1 307068458 9727853 1733676..1733927 1 NC_014494.1 Operon 832 Gene 2 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase 1733927 9727853 SPAP_1839 Streptococcus pneumoniae AP200 lactoylglutathione lyase-like lyase YP_003877424.1 1733676 D 574093 CDS YP_003877425.1 307068459 9727854 1733934..1734062 1 NC_014494.1 Operon 832 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1734062 9727854 SPAP_1840 Streptococcus pneumoniae AP200 hypothetical protein YP_003877425.1 1733934 D 574093 CDS YP_003877426.1 307068460 9727855 1734798..1734917 1 NC_014494.1 Operon 833 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1734917 9727855 SPAP_1841 Streptococcus pneumoniae AP200 hypothetical protein YP_003877426.1 1734798 D 574093 CDS YP_003877427.1 307068461 9727856 1734940..1735521 1 NC_014494.1 Operon 833 Gene 2 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein 1735521 9727856 SPAP_1842 Streptococcus pneumoniae AP200 adenine/guanine phosphoribosyltransferases-like PRPP-binding protein YP_003877427.1 1734940 D 574093 CDS YP_003877428.1 307068462 9727857 1735521..1736783 1 NC_014494.1 Operon 833 Gene 3 COG2233 Xanthine/uracil permeases; Xanthine/uracil permease 1736783 9727857 SPAP_1843 Streptococcus pneumoniae AP200 Xanthine/uracil permease YP_003877428.1 1735521 D 574093 CDS YP_003877429.1 307068463 9727858 complement(1736870..1737736) 1 NC_014494.1 Operon 834 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1737736 9727858 SPAP_1844 Streptococcus pneumoniae AP200 hypothetical protein YP_003877429.1 1736870 R 574093 CDS YP_003877430.1 307068464 9727859 complement(1737723..1738493) 1 NC_014494.1 Operon 834 Gene 2 COG0863 DNA modification methylase; DNA modification methylase 1738493 9727859 SPAP_1845 Streptococcus pneumoniae AP200 DNA modification methylase YP_003877430.1 1737723 R 574093 CDS YP_003877431.1 307068465 9727860 complement(1738519..1739373) 1 NC_014494.1 Operon 834 Gene 3 COG0338 Site-specific DNA methylase; site-specific DNA methylase 1739373 9727860 SPAP_1846 Streptococcus pneumoniae AP200 site-specific DNA methylase YP_003877431.1 1738519 R 574093 CDS YP_003877432.1 307068466 9727861 complement(1739530..1739934) 1 NC_014494.1 Operon 835 Gene 1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 1739934 9727861 SPAP_1847 Streptococcus pneumoniae AP200 hypothetical protein YP_003877432.1 1739530 R 574093 CDS YP_003877433.1 307068467 9727862 complement(1740004..1741485) 1 NC_014494.1 Operon 835 Gene 2 COG4468 Galactose-1-phosphate uridyltransferase; galactose-1-phosphate uridyltransferase 1741485 9727862 SPAP_1848 Streptococcus pneumoniae AP200 galactose-1-phosphate uridyltransferase YP_003877433.1 1740004 R 574093 CDS YP_003877434.1 307068468 9727863 complement(1741504..1742682) 1 NC_014494.1 Operon 835 Gene 3 COG0153 Galactokinase; galactokinase 1742682 9727863 SPAP_1849 Streptococcus pneumoniae AP200 galactokinase YP_003877434.1 1741504 R 574093 CDS YP_003877435.1 307068469 9727864 1742847..1743854 1 NC_014494.1 Operon 836 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator 1743854 9727864 SPAP_1850 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877435.1 1742847 D 574093 CDS YP_003877436.1 307068470 9727865 complement(1743900..1744937) 1 NC_014494.1 Operon 837 Gene 1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase 1744937 9727865 SPAP_1851 Streptococcus pneumoniae AP200 threonine dehydrogenase-like Zn-dependent dehydrogenase YP_003877436.1 1743900 R 574093 CDS YP_003877437.1 307068471 9727866 complement(1744938..1745291) 1 NC_014494.1 Operon 837 Gene 2 COG0789 Predicted transcriptional regulators; putative transcriptional regulator 1745291 9727866 SPAP_1852 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877437.1 1744938 R 574093 CDS YP_003877438.1 307068472 9727867 complement(1745535..1746425) 1 NC_014494.1 Operon 838 Gene 1 COG1230 Co/Zn/Cd efflux system component; Co/Zn/Cd efflux system protein 1746425 9727867 SPAP_1853 Streptococcus pneumoniae AP200 Co/Zn/Cd efflux system protein YP_003877438.1 1745535 R 574093 CDS YP_003877439.1 307068473 9727868 1746558..1747094 1 NC_014494.1 Operon 839 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 1747094 9727868 SPAP_1854 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877439.1 1746558 D 574093 CDS YP_003877440.1 307068474 9727869 complement(1747261..1748067) 1 NC_014494.1 Operon 840 Gene 1 COG3201 Nicotinamide mononucleotide transporter; nicotinamide mononucleotide transporter 1748067 9727869 SPAP_1855 Streptococcus pneumoniae AP200 nicotinamide mononucleotide transporter YP_003877440.1 1747261 R 574093 CDS YP_003877441.1 307068475 9727870 complement(1748412..1749932) 1 NC_014494.1 Operon 841 Gene 1 COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system; osmoprotectant binding protein; ABC transporter periplasmic glycine betaine/choline-binding (lipo)protein 1749932 9727870 SPAP_1856 Streptococcus pneumoniae AP200 ABC transporter periplasmic glycine betaine/choline-binding (lipo)protein YP_003877441.1 1748412 R 574093 CDS YP_003877442.1 307068476 9727871 complement(1749925..1750653) 1 NC_014494.1 Operon 841 Gene 2 COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; proline/glycine betaine ABC transporter ATPase 1750653 9727871 SPAP_1857 Streptococcus pneumoniae AP200 proline/glycine betaine ABC transporter ATPase YP_003877442.1 1749925 R 574093 CDS YP_003877443.1 307068477 9727872 complement(1750668..1751432) 1 NC_014494.1 Operon 841 Gene 3 COG4922 Uncharacterized protein conserved in bacteria; hypothetical protein 1751432 9727872 SPAP_1858 Streptococcus pneumoniae AP200 hypothetical protein YP_003877443.1 1750668 R 574093 CDS YP_003877444.1 307068478 9727873 complement(1751436..1751879) 1 NC_014494.1 Operon 841 Gene 4 COG1846 Transcriptional regulators; transcriptional regulator 1751879 9727873 SPAP_1859 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877444.1 1751436 R 574093 CDS YP_003877445.1 307068479 9727874 complement(1752561..1752857) 1 NC_014494.1 Operon 842 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1752857 9727874 SPAP_1860 Streptococcus pneumoniae AP200 hypothetical protein YP_003877445.1 1752561 R 574093 CDS YP_003877446.1 307068480 9727875 complement(1752879..1753943) 1 NC_014494.1 Operon 842 Gene 2 COG1363 Cellulase M and related proteins; cellulase M-like proteins 1753943 9727875 SPAP_1861 Streptococcus pneumoniae AP200 cellulase M-like proteins YP_003877446.1 1752879 R 574093 CDS YP_003877447.1 307068481 9727876 1754343..1755044 1 NC_014494.1 Operon 843 Gene 1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1755044 9727876 SPAP_1862 Streptococcus pneumoniae AP200 UDP-glucose 4-epimerase YP_003877447.1 1754343 D 574093 CDS YP_003877448.1 307068482 9727877 1755467..1756426 1 NC_014494.1 Operon 844 Gene 1 COG4606 ABC-type enterochelin transport system, permease component; enterochelin ABC transporter permease 1756426 9727877 SPAP_1863 Streptococcus pneumoniae AP200 enterochelin ABC transporter permease YP_003877448.1 1755467 D 574093 CDS YP_003877449.1 307068483 9727878 1756416..1757372 1 NC_014494.1 Operon 844 Gene 2 COG4605 ABC-type enterochelin transport system, permease component; enterochelin ABC transporter permease 1757372 9727878 SPAP_1864 Streptococcus pneumoniae AP200 enterochelin ABC transporter permease YP_003877449.1 1756416 D 574093 CDS YP_003877450.1 307068484 9727879 1757369..1758121 1 NC_014494.1 Operon 844 Gene 3 COG4604 ABC-type enterochelin transport system, ATPase component; enterochelin ABC transporter ATPase 1758121 9727879 SPAP_1865 Streptococcus pneumoniae AP200 enterochelin ABC transporter ATPase YP_003877450.1 1757369 D 574093 CDS YP_003877451.1 307068485 9727880 1758217..1759182 1 NC_014494.1 Operon 844 Gene 4 COG4607 ABC-type enterochelin transport system, periplasmic component; enterochelin ABC transporter periplasmic protein 1759182 9727880 SPAP_1866 Streptococcus pneumoniae AP200 enterochelin ABC transporter periplasmic protein YP_003877451.1 1758217 D 574093 CDS YP_003877452.1 307068486 9727881 complement(1759407..1759649) 1 NC_014494.1 Operon 845 Gene 1 COG0759 Uncharacterized conserved protein; hypothetical protein 1759649 9727881 SPAP_1867 Streptococcus pneumoniae AP200 hypothetical protein YP_003877452.1 1759407 R 574093 CDS YP_003877453.1 307068487 9727882 complement(1759649..1760371) 1 NC_014494.1 Operon 845 Gene 2 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase 1760371 9727882 SPAP_1868 Streptococcus pneumoniae AP200 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase YP_003877453.1 1759649 R 574093 CDS YP_003877454.1 307068488 9727883 complement(1760358..1760927) 1 NC_014494.1 Operon 845 Gene 3 COG1386 Predicted transcriptional regulator containing the HTH domain; putative transcriptional regulator 1760927 9727883 SPAP_1869 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877454.1 1760358 R 574093 CDS YP_003877455.1 307068489 9727884 complement(1760946..1761674) 1 NC_014494.1 Operon 845 Gene 4 COG1354 Uncharacterized conserved protein; hypothetical protein 1761674 9727884 SPAP_1870 Streptococcus pneumoniae AP200 hypothetical protein YP_003877455.1 1760946 R 574093 CDS YP_003877456.1 307068490 9727885 complement(1761678..1762415) 1 NC_014494.1 Operon 845 Gene 5 COG0582 Integrase; integrase 1762415 9727885 SPAP_1871 Streptococcus pneumoniae AP200 integrase YP_003877456.1 1761678 R 574093 CDS YP_003877457.1 307068491 9727886 complement(1762406..1762867) 1 NC_014494.1 Operon 845 Gene 6 COG0517 FOG: CBS domain; hypothetical protein 1762867 9727886 SPAP_1872 Streptococcus pneumoniae AP200 hypothetical protein YP_003877457.1 1762406 R 574093 CDS YP_003877458.1 307068492 9727887 complement(1762864..1763385) 1 NC_014494.1 Operon 845 Gene 7 COG0622 Predicted phosphoesterase; putative phosphoesterase 1763385 9727887 SPAP_1873 Streptococcus pneumoniae AP200 putative phosphoesterase YP_003877458.1 1762864 R 574093 CDS YP_003877459.1 307068493 9727888 complement(1763361..1764332) 1 NC_014494.1 Operon 845 Gene 8 protein supported gi|157155704|ref|YP_001464307.1| putative deoxyribonucleotide triphosphate pyrophosphatase; hypothetical protein 1764332 9727888 SPAP_1874 Streptococcus pneumoniae AP200 hypothetical protein YP_003877459.1 1763361 R 574093 CDS YP_003877460.1 307068494 9727889 complement(1764329..1765123) 1 NC_014494.1 Operon 845 Gene 9 COG0796 Glutamate racemase; glutamate racemase 1765123 9727889 SPAP_1875 Streptococcus pneumoniae AP200 glutamate racemase YP_003877460.1 1764329 R 574093 CDS YP_003877461.1 307068495 9727890 complement(1765344..1765580) 1 NC_014494.1 Operon 846 Gene 1 COG3763 Uncharacterized protein conserved in bacteria; hypothetical protein 1765580 9727890 SPAP_1876 Streptococcus pneumoniae AP200 hypothetical protein YP_003877461.1 1765344 R 574093 CDS YP_003877462.1 307068496 9727891 complement(1765836..1767461) 1 NC_014494.1 Operon 847 Gene 1 COG0366 Glycosidases; glycosidase 1767461 9727891 SPAP_1877 Streptococcus pneumoniae AP200 glycosidase YP_003877462.1 1765836 R 574093 CDS YP_003877463.1 307068497 9727892 complement(1767639..1769606) 1 NC_014494.1 Operon 847 Gene 2 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 1769606 9727892 SPAP_1878 Streptococcus pneumoniae AP200 PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC YP_003877463.1 1767639 R 574093 CDS YP_003877464.1 307068498 9727893 1769791..1770501 1 NC_014494.1 Operon 848 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 1770501 9727893 SPAP_1879 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877464.1 1769791 D 574093 CDS YP_003877465.1 307068499 9727894 complement(1770534..1771337) 1 NC_014494.1 Operon 849 Gene 1 COG1101 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase 1771337 9727894 SPAP_1880 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003877465.1 1770534 R 574093 CDS YP_003877466.1 307068500 9727895 complement(1771350..1771778) 1 NC_014494.1 Operon 849 Gene 2 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease 1771778 9727895 SPAP_1881 Streptococcus pneumoniae AP200 ABC transporter permease YP_003877466.1 1771350 R 574093 CDS YP_003877467.1 307068501 9727896 complement(1771787..1772227) 1 NC_014494.1 Operon 849 Gene 3 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease 1772227 9727896 SPAP_1882 Streptococcus pneumoniae AP200 ABC transporter permease YP_003877467.1 1771787 R 574093 CDS YP_003877468.1 307068502 9727897 complement(1772239..1772601) 1 NC_014494.1 Operon 849 Gene 4 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic 1772601 9727897 SPAP_1883 Streptococcus pneumoniae AP200 ABC transporter periplasmic YP_003877468.1 1772239 R 574093 CDS YP_003877469.1 307068503 9727898 complement(1772662..1773048) 1 NC_014494.1 Operon 849 Gene 5 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic 1773048 9727898 SPAP_1884 Streptococcus pneumoniae AP200 ABC transporter periplasmic YP_003877469.1 1772662 R 574093 CDS YP_003877470.1 307068504 9727899 complement(1773666..1774622) 1 NC_014494.1 Operon 850 Gene 1 protein supported gi|163765018|ref|ZP_02172066.1| ribosomal protein L9; hypothetical protein 1774622 9727899 SPAP_1885 Streptococcus pneumoniae AP200 hypothetical protein YP_003877470.1 1773666 R 574093 CDS YP_003877471.1 307068505 9727900 complement(1774603..1775670) 1 NC_014494.1 Operon 850 Gene 2 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide/oligopeptide/nickel ABC transporter ATPase 1775670 9727900 SPAP_1886 Streptococcus pneumoniae AP200 dipeptide/oligopeptide/nickel ABC transporter ATPase YP_003877471.1 1774603 R 574093 CDS YP_003877472.1 307068506 9727901 complement(1775679..1776605) 1 NC_014494.1 Operon 850 Gene 3 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease 1776605 9727901 SPAP_1887 Streptococcus pneumoniae AP200 dipeptide/oligopeptide/nickel ABC transporter permease YP_003877472.1 1775679 R 574093 CDS YP_003877473.1 307068507 9727902 complement(1776605..1778101) 1 NC_014494.1 Operon 850 Gene 4 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease 1778101 9727902 SPAP_1888 Streptococcus pneumoniae AP200 dipeptide/oligopeptide/nickel ABC transporter permease YP_003877473.1 1776605 R 574093 CDS YP_003877474.1 307068508 9727903 complement(1778168..1780147) 1 NC_014494.1 Operon 850 Gene 5 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic protein 1780147 9727903 SPAP_1889 Streptococcus pneumoniae AP200 oligopeptide ABC transporter periplasmic protein YP_003877474.1 1778168 R 574093 CDS YP_003877475.1 307068509 9727904 1780274..1780441 1 NC_014494.1 Operon 851 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1780441 9727904 SPAP_1890 Streptococcus pneumoniae AP200 hypothetical protein YP_003877475.1 1780274 D 574093 CDS YP_003877476.1 307068510 9727905 complement(1780833..1782026) 1 NC_014494.1 Operon 852 Gene 1 COG3307 Lipid A core - O-antigen ligase and related enzymes; lipid A core - O-antigen ligase-like enzyme 1782026 9727905 SPAP_1891 Streptococcus pneumoniae AP200 lipid A core - O-antigen ligase-like enzyme YP_003877476.1 1780833 R 574093 CDS YP_003877477.1 307068511 9727906 complement(1782164..1783606) 1 NC_014494.1 Operon 853 Gene 1 COG0366 Glycosidases; glycosidase 1783606 9727906 SPAP_1892 Streptococcus pneumoniae AP200 glycosidase YP_003877477.1 1782164 R 574093 CDS YP_003877478.1 307068512 9727907 complement(1783917..1784750) 1 NC_014494.1 Operon 854 Gene 1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 1784750 9727907 SPAP_1893 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877478.1 1783917 R 574093 CDS YP_003877479.1 307068513 9727908 complement(1784764..1785630) 1 NC_014494.1 Operon 854 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1785630 9727908 SPAP_1894 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877479.1 1784764 R 574093 CDS YP_003877480.1 307068514 9727909 complement(1785644..1786903) 1 NC_014494.1 Operon 854 Gene 3 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 1786903 9727909 SPAP_1895 Streptococcus pneumoniae AP200 sugar ABC transporter periplasmic protein YP_003877480.1 1785644 R 574093 CDS YP_003877481.1 307068515 9727910 complement(1786938..1789100) 1 NC_014494.1 Operon 854 Gene 4 COG3345 Alpha-galactosidase; alpha-galactosidase 1789100 9727910 SPAP_1896 Streptococcus pneumoniae AP200 alpha-galactosidase YP_003877481.1 1786938 R 574093 CDS YP_003877482.1 307068516 9727911 1789208..1790068 1 NC_014494.1 Operon 855 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein 1790068 9727911 SPAP_1897 Streptococcus pneumoniae AP200 AraC-type DNA-binding domain-containing protein YP_003877482.1 1789208 D 574093 CDS YP_003877483.1 307068517 9727912 1790065..1791000 1 NC_014494.1 Operon 855 Gene 2 COG0340 Biotin-(acetyl-CoA carboxylase) ligase; biotin-(acetyl-CoA carboxylase) ligase 1791000 9727912 SPAP_1898 Streptococcus pneumoniae AP200 biotin-(acetyl-CoA carboxylase) ligase YP_003877483.1 1790065 D 574093 CDS YP_003877484.1 307068518 9727933 complement(1797918..1799273) 1 NC_014494.1 Operon 856 Gene 1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; SAM-dependent methyltransferase 1799273 9727933 SPAP_1919 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003877484.1 1797918 R 574093 CDS YP_003877485.1 307068519 9727934 1799353..1800087 1 NC_014494.1 Operon 857 Gene 1 COG2137 Uncharacterized protein conserved in bacteria; hypothetical protein 1800087 9727934 SPAP_1920 Streptococcus pneumoniae AP200 hypothetical protein YP_003877485.1 1799353 D 574093 CDS YP_003877486.1 307068520 9727935 1800176..1800709 1 NC_014494.1 Operon 857 Gene 2 COG3557 Uncharacterized domain/protein associated with RNAses G and E; hypothetical protein 1800709 9727935 SPAP_1921 Streptococcus pneumoniae AP200 hypothetical protein YP_003877486.1 1800176 D 574093 CDS YP_003877487.1 307068521 9727936 complement(1801063..1801410) 1 NC_014494.1 Operon 858 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1801410 9727936 SPAP_1922 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877487.1 1801063 R 574093 CDS YP_003877488.1 307068522 9727937 complement(1801931..1802704) 1 NC_014494.1 Operon 859 Gene 1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 1802704 9727937 SPAP_1923 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003877488.1 1801931 R 574093 CDS YP_003877489.1 307068523 9727938 complement(1803152..1803478) 1 NC_014494.1 Operon 860 Gene 1 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 1803478 9727938 SPAP_1924 Streptococcus pneumoniae AP200 hypothetical protein YP_003877489.1 1803152 R 574093 CDS YP_003877490.1 307068524 9727939 complement(1803578..1803742) 1 NC_014494.1 Operon 860 Gene 2 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein 1803742 9727939 SPAP_1925 Streptococcus pneumoniae AP200 hypothetical protein YP_003877490.1 1803578 R 574093 CDS YP_003877491.1 307068525 9727940 complement(1803815..1803907) 1 NC_014494.1 Operon 860 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1803907 9727940 SPAP_1926 Streptococcus pneumoniae AP200 hypothetical protein YP_003877491.1 1803815 R 574093 CDS YP_003877492.1 307068526 9727941 complement(1804045..1805667) 1 NC_014494.1 Operon 861 Gene 1 protein supported gi|167855908|ref|ZP_02478658.1| 50S ribosomal protein L28; hypothetical protein 1805667 9727941 SPAP_1927 Streptococcus pneumoniae AP200 hypothetical protein YP_003877492.1 1804045 R 574093 CDS YP_003877493.1 307068527 9727942 complement(1805683..1805967) 1 NC_014494.1 Operon 861 Gene 2 COG0234 Co-chaperonin GroES (HSP10); co-chaperonin GroES 1805967 9727942 SPAP_1928 Streptococcus pneumoniae AP200 co-chaperonin GroES YP_003877493.1 1805683 R 574093 CDS YP_003877494.1 307068528 9727943 complement(1806237..1806632) 1 NC_014494.1 Operon 862 Gene 1 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein 1806632 9727943 SPAP_1929 Streptococcus pneumoniae AP200 single-stranded DNA-binding protein YP_003877494.1 1806237 R 574093 CDS YP_003877495.1 307068529 9727944 complement(1806710..1807471) 1 NC_014494.1 Operon 862 Gene 2 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short-chain alcohol dehydrogenase of unknown specificity 1807471 9727944 SPAP_1930 Streptococcus pneumoniae AP200 short-chain alcohol dehydrogenase of unknown specificity YP_003877495.1 1806710 R 574093 CDS YP_003877496.1 307068530 9727945 complement(1807504..1808130) 1 NC_014494.1 Operon 862 Gene 3 COG0073 EMAP domain; EMAP domain protein 1808130 9727945 SPAP_1931 Streptococcus pneumoniae AP200 EMAP domain protein YP_003877496.1 1807504 R 574093 CDS YP_003877497.1 307068531 9727946 complement(1808146..1808463) 1 NC_014494.1 Operon 862 Gene 4 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 1808463 9727946 SPAP_1932 Streptococcus pneumoniae AP200 thiol-disulfide isomerase and thioredoxin YP_003877497.1 1808146 R 574093 CDS YP_003877498.1 307068532 9727947 complement(1808460..1808729) 1 NC_014494.1 Operon 862 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 1808729 9727947 SPAP_1933 Streptococcus pneumoniae AP200 hypothetical protein YP_003877498.1 1808460 R 574093 CDS YP_003877499.1 307068533 9727948 complement(1809044..1809259) 1 NC_014494.1 Operon 863 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1809259 9727948 SPAP_1934 Streptococcus pneumoniae AP200 hypothetical protein YP_003877499.1 1809044 R 574093 CDS YP_003877500.1 307068534 9727949 complement(1809396..1810070) 1 NC_014494.1 Operon 864 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1810070 9727949 SPAP_1935 Streptococcus pneumoniae AP200 hypothetical protein YP_003877500.1 1809396 R 574093 CDS YP_003877501.1 307068535 9727950 complement(1810076..1810522) 1 NC_014494.1 Operon 864 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 1810522 9727950 SPAP_1936 Streptococcus pneumoniae AP200 LytR/AlgR family response regulator YP_003877501.1 1810076 R 574093 CDS YP_003877502.1 307068536 9727951 complement(1810624..1811139) 1 NC_014494.1 Operon 865 Gene 1 COG0671 Membrane-associated phospholipid phosphatase; membrane-associated phospholipid phosphatase 1811139 9727951 SPAP_1937 Streptococcus pneumoniae AP200 membrane-associated phospholipid phosphatase YP_003877502.1 1810624 R 574093 CDS YP_003877503.1 307068537 9727952 complement(1811136..1811498) 1 NC_014494.1 Operon 865 Gene 2 COG4898 Uncharacterized protein conserved in bacteria; hypothetical protein 1811498 9727952 SPAP_1938 Streptococcus pneumoniae AP200 hypothetical protein YP_003877503.1 1811136 R 574093 CDS YP_003877504.1 307068538 9727953 complement(1811564..1812580) 1 NC_014494.1 Operon 866 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1812580 9727953 SPAP_1939 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877504.1 1811564 R 574093 CDS YP_003877505.1 307068539 9727954 complement(1812602..1813423) 1 NC_014494.1 Operon 866 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1813423 9727954 SPAP_1940 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877505.1 1812602 R 574093 CDS YP_003877506.1 307068540 9727955 complement(1813440..1813910) 1 NC_014494.1 Operon 866 Gene 3 COG1846 Transcriptional regulators; transcriptional regulator 1813910 9727955 SPAP_1941 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877506.1 1813440 R 574093 CDS YP_003877507.1 307068541 9727956 complement(1814034..1814750) 1 NC_014494.1 Operon 867 Gene 1 COG0217 Uncharacterized conserved protein; hypothetical protein 1814750 9727956 SPAP_1942 Streptococcus pneumoniae AP200 hypothetical protein YP_003877507.1 1814034 R 574093 CDS YP_003877508.1 307068542 9727957 complement(1815631..1817046) 1 NC_014494.1 pneumolysin (thiol-activated cytolysin); hypothetical protein 1817046 9727957 SPAP_1943 Streptococcus pneumoniae AP200 hypothetical protein YP_003877508.1 1815631 R 574093 CDS YP_003877509.1 307068543 9727958 complement(1817057..1817467) 1 NC_014494.1 Operon 868 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1817467 9727958 SPAP_1944 Streptococcus pneumoniae AP200 hypothetical protein YP_003877509.1 1817057 R 574093 CDS YP_003877510.1 307068544 9727959 complement(1817460..1818068) 1 NC_014494.1 Operon 868 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1818068 9727959 SPAP_1945 Streptococcus pneumoniae AP200 hypothetical protein YP_003877510.1 1817460 R 574093 CDS YP_003877511.1 307068545 9727960 complement(1818081..1818539) 1 NC_014494.1 Operon 868 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1818539 9727960 SPAP_1946 Streptococcus pneumoniae AP200 hypothetical protein YP_003877511.1 1818081 R 574093 CDS YP_003877512.1 307068546 9727961 1818664..1818795 1 NC_014494.1 Operon 869 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1818795 9727961 SPAP_1947 Streptococcus pneumoniae AP200 hypothetical protein YP_003877512.1 1818664 D 574093 CDS YP_003877513.1 307068547 9727962 1818800..1819063 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1819063 9727962 SPAP_1948 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003877513.1 1818800 D 574093 CDS YP_003877514.1 307068548 9727963 complement(1819827..1820087) 1 NC_014494.1 Operon 870 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1820087 9727963 SPAP_1949 Streptococcus pneumoniae AP200 hypothetical protein YP_003877514.1 1819827 R 574093 CDS YP_003877515.1 307068549 9727964 complement(1820146..1820697) 1 NC_014494.1 Operon 870 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1820697 9727964 SPAP_1950 Streptococcus pneumoniae AP200 hypothetical protein YP_003877515.1 1820146 R 574093 CDS YP_003877516.1 307068550 9727965 complement(1820687..1820884) 1 NC_014494.1 Operon 870 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1820884 9727965 SPAP_1951 Streptococcus pneumoniae AP200 hypothetical protein YP_003877516.1 1820687 R 574093 CDS YP_003877517.1 307068551 9727966 complement(1820903..1821682) 1 NC_014494.1 Operon 870 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1821682 9727966 SPAP_1952 Streptococcus pneumoniae AP200 hypothetical protein YP_003877517.1 1820903 R 574093 CDS YP_003877518.1 307068552 9727967 complement(1822090..1822515) 1 NC_014494.1 Operon 871 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1822515 9727967 SPAP_1953 Streptococcus pneumoniae AP200 hypothetical protein YP_003877518.1 1822090 R 574093 CDS YP_003877519.1 307068553 9727968 complement(1822644..1822892) 1 NC_014494.1 Operon 872 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1822892 9727968 SPAP_1954 Streptococcus pneumoniae AP200 hypothetical protein YP_003877519.1 1822644 R 574093 CDS YP_003877520.1 307068554 9727969 complement(1823049..1823255) 1 NC_014494.1 Operon 873 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1823255 9727969 SPAP_1955 Streptococcus pneumoniae AP200 hypothetical protein YP_003877520.1 1823049 R 574093 CDS YP_003877521.1 307068555 9727970 complement(1823242..1823403) 1 NC_014494.1 Operon 873 Gene 2 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1823403 9727970 SPAP_1956 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877521.1 1823242 R 574093 CDS YP_003877522.1 307068556 9727971 complement(1823762..1824718) 1 NC_014494.1 Operon 874 Gene 1 COG5263 FOG: Glucan-binding domain (YG repeat); glucan-binding domain-containing protein 1824718 9727971 SPAP_1957 Streptococcus pneumoniae AP200 glucan-binding domain-containing protein YP_003877522.1 1823762 R 574093 CDS YP_003877523.1 307068557 9727972 complement(1825094..1826464) 1 NC_014494.1 Operon 875 Gene 1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1826464 9727972 SPAP_1958 Streptococcus pneumoniae AP200 Na+-driven multidrug efflux pump YP_003877523.1 1825094 R 574093 CDS YP_003877524.1 307068558 9727973 complement(1826771..1827937) 1 NC_014494.1 Operon 876 Gene 1 COG0468 RecA/RadA recombinase; recombinase A 1827937 9727973 SPAP_1959 Streptococcus pneumoniae AP200 recombinase A YP_003877524.1 1826771 R 574093 CDS YP_003877525.1 307068559 9727974 complement(1827992..1829248) 1 NC_014494.1 Operon 876 Gene 2 COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; putative nucleotide-utilizing enzyme 1829248 9727974 SPAP_1960 Streptococcus pneumoniae AP200 putative nucleotide-utilizing enzyme YP_003877525.1 1827992 R 574093 CDS YP_003877526.1 307068560 9727975 complement(1829333..1830349) 1 NC_014494.1 Operon 877 Gene 1 COG1316 Transcriptional regulator; transcriptional regulator 1830349 9727975 SPAP_1961 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877526.1 1829333 R 574093 CDS YP_003877527.1 307068561 9727976 complement(1830357..1830875) 1 NC_014494.1 Operon 877 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1830875 9727976 SPAP_1962 Streptococcus pneumoniae AP200 histone acetyltransferase HPA2-like acetyltransferase YP_003877527.1 1830357 R 574093 CDS YP_003877528.1 307068562 9727977 complement(1830865..1831308) 1 NC_014494.1 Operon 877 Gene 3 COG0802 Predicted ATPase or kinase; putative ATPase 1831308 9727977 SPAP_1963 Streptococcus pneumoniae AP200 putative ATPase YP_003877528.1 1830865 R 574093 CDS YP_003877529.1 307068563 9727978 complement(1831394..1832014) 1 NC_014494.1 Operon 877 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1832014 9727978 SPAP_1964 Streptococcus pneumoniae AP200 hypothetical protein YP_003877529.1 1831394 R 574093 CDS YP_003877530.1 307068564 9727979 complement(1832397..1833260) 1 NC_014494.1 Operon 878 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1833260 9727979 SPAP_1965 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877530.1 1832397 R 574093 CDS YP_003877531.1 307068565 9727980 1833606..1835621 1 NC_014494.1 Operon 879 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 1835621 9727980 SPAP_1966 Streptococcus pneumoniae AP200 hypothetical protein YP_003877531.1 1833606 D 574093 CDS YP_003877532.1 307068566 9727981 1835623..1836255 1 NC_014494.1 Operon 879 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1836255 9727981 SPAP_1967 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003877532.1 1835623 D 574093 CDS YP_003877533.1 307068567 9727982 1836396..1836674 1 NC_014494.1 Operon 880 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1836674 9727982 SPAP_1968 Streptococcus pneumoniae AP200 hypothetical protein YP_003877533.1 1836396 D 574093 CDS YP_003877534.1 307068568 9727983 complement(1837184..1837597) 1 NC_014494.1 Operon 881 Gene 1 COG0105 Nucleoside diphosphate kinase; nucleoside diphosphate kinase 1837597 9727983 SPAP_1969 Streptococcus pneumoniae AP200 nucleoside diphosphate kinase YP_003877534.1 1837184 R 574093 CDS YP_003877535.1 307068569 9727984 complement(1837708..1841385) 1 NC_014494.1 Operon 882 Gene 1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunits beta'/160 kD subunit 1841385 9727984 SPAP_1970 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase subunits beta'/160 kD subunit YP_003877535.1 1837708 R 574093 CDS YP_003877536.1 307068570 9727985 complement(1841418..1845029) 1 NC_014494.1 Operon 882 Gene 2 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta/140 kD subunit 1845029 9727985 SPAP_1971 Streptococcus pneumoniae AP200 DNA-directed RNA polymerase subunit beta/140 kD subunit YP_003877536.1 1841418 R 574093 CDS YP_003877537.1 307068571 9727987 complement(1845713..1847044) 1 NC_014494.1 Operon 883 Gene 1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysins-like protein 1847044 9727987 SPAP_1973 Streptococcus pneumoniae AP200 hemolysins-like protein YP_003877537.1 1845713 R 574093 CDS YP_003877538.1 307068572 9727988 complement(1847335..1848159) 1 NC_014494.1 Operon 884 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1848159 9727988 SPAP_1974 Streptococcus pneumoniae AP200 hypothetical protein YP_003877538.1 1847335 R 574093 CDS YP_003877539.1 307068573 9727989 complement(1848198..1848392) 1 NC_014494.1 Operon 884 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1848392 9727989 SPAP_1975 Streptococcus pneumoniae AP200 hypothetical protein YP_003877539.1 1848198 R 574093 CDS YP_003877540.1 307068574 9727990 complement(1848379..1849662) 1 NC_014494.1 Operon 884 Gene 3 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine enolpyruvyl transferase 1849662 9727990 SPAP_1976 Streptococcus pneumoniae AP200 UDP-N-acetylglucosamine enolpyruvyl transferase YP_003877540.1 1848379 R 574093 CDS YP_003877541.1 307068575 9727991 complement(1849686..1849916) 1 NC_014494.1 Operon 884 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1849916 9727991 SPAP_1977 Streptococcus pneumoniae AP200 hypothetical protein YP_003877541.1 1849686 R 574093 CDS YP_003877542.1 307068576 9727992 complement(1849974..1851011) 1 NC_014494.1 Operon 884 Gene 5 COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein 1851011 9727992 SPAP_1978 Streptococcus pneumoniae AP200 hypothetical protein YP_003877542.1 1849974 R 574093 CDS YP_003877543.1 307068577 9727993 complement(1850995..1851306) 1 NC_014494.1 Operon 884 Gene 6 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase 1851306 9727993 SPAP_1979 Streptococcus pneumoniae AP200 phosphopantetheine adenylyltransferase YP_003877543.1 1850995 R 574093 CDS YP_003877544.1 307068578 9727994 complement(1851315..1851482) 1 NC_014494.1 Operon 884 Gene 7 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase 1851482 9727994 SPAP_1980 Streptococcus pneumoniae AP200 phosphopantetheine adenylyltransferase YP_003877544.1 1851315 R 574093 CDS YP_003877545.1 307068579 9727995 complement(1851472..1852011) 1 NC_014494.1 Operon 884 Gene 8 COG0742 N6-adenine-specific methylase; N6-adenine-specific methylase 1852011 9727995 SPAP_1981 Streptococcus pneumoniae AP200 N6-adenine-specific methylase YP_003877545.1 1851472 R 574093 CDS YP_003877546.1 307068580 9727996 complement(1852076..1853068) 1 NC_014494.1 Operon 884 Gene 9 COG2502 Asparagine synthetase A; asparagine synthetase A 1853068 9727996 SPAP_1982 Streptococcus pneumoniae AP200 asparagine synthetase A YP_003877546.1 1852076 R 574093 CDS YP_003877547.1 307068581 9727997 complement(1853179..1853862) 1 NC_014494.1 Operon 885 Gene 1 COG0670 Integral membrane protein, interacts with FtsH; integral membrane protein 1853862 9727997 SPAP_1983 Streptococcus pneumoniae AP200 integral membrane protein YP_003877547.1 1853179 R 574093 CDS YP_003877548.1 307068582 9727998 complement(1853918..1854658) 1 NC_014494.1 Operon 885 Gene 2 COG0566 rRNA methylases; rRNA methylase 1854658 9727998 SPAP_1984 Streptococcus pneumoniae AP200 rRNA methylase YP_003877548.1 1853918 R 574093 CDS YP_003877549.1 307068583 9727999 1854692..1854970 1 NC_014494.1 Operon 886 Gene 1 COG1254 Acylphosphatases; acylphosphatase 1854970 9727999 SPAP_1985 Streptococcus pneumoniae AP200 acylphosphatase YP_003877549.1 1854692 D 574093 CDS YP_003877550.1 307068584 9728000 1855048..1855974 1 NC_014494.1 Operon 886 Gene 2 COG0706 Preprotein translocase subunit YidC; preprotein translocase subunit YidC 1855974 9728000 SPAP_1986 Streptococcus pneumoniae AP200 preprotein translocase subunit YidC YP_003877550.1 1855048 D 574093 CDS YP_003877551.1 307068585 9728001 complement(1856049..1856843) 1 NC_014494.1 Operon 887 Gene 1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate-formate lyase-activating enzyme 1856843 9728001 SPAP_1987 Streptococcus pneumoniae AP200 pyruvate-formate lyase-activating enzyme YP_003877551.1 1856049 R 574093 CDS YP_003877552.1 307068586 9728002 complement(1856969..1858219) 1 NC_014494.1 Operon 888 Gene 1 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 1858219 9728002 SPAP_1988 Streptococcus pneumoniae AP200 diaminopimelate decarboxylase YP_003877552.1 1856969 R 574093 CDS YP_003877553.1 307068587 9728003 complement(1858286..1859113) 1 NC_014494.1 Operon 888 Gene 2 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein 1859113 9728003 SPAP_1989 Streptococcus pneumoniae AP200 adenine/guanine phosphoribosyltransferases-like PRPP-binding protein YP_003877553.1 1858286 R 574093 CDS YP_003877554.1 307068588 9728004 complement(1859380..1860321) 1 NC_014494.1 Operon 889 Gene 1 COG3481 Predicted HD-superfamily hydrolase; putative HD superfamily hydrolase 1860321 9728004 SPAP_1990 Streptococcus pneumoniae AP200 putative HD superfamily hydrolase YP_003877554.1 1859380 R 574093 CDS YP_003877555.1 307068589 9728005 complement(1860311..1861567) 1 NC_014494.1 Operon 889 Gene 2 COG1322 Uncharacterized protein conserved in bacteria; hypothetical protein 1861567 9728005 SPAP_1991 Streptococcus pneumoniae AP200 hypothetical protein YP_003877555.1 1860311 R 574093 CDS YP_003877556.1 307068590 9728006 complement(1861569..1862231) 1 NC_014494.1 Operon 889 Gene 3 COG1564 Thiamine pyrophosphokinase; thiamine pyrophosphokinase 1862231 9728006 SPAP_1992 Streptococcus pneumoniae AP200 thiamine pyrophosphokinase YP_003877556.1 1861569 R 574093 CDS YP_003877557.1 307068591 9728007 complement(1862194..1862850) 1 NC_014494.1 Operon 889 Gene 4 COG0036 Pentose-5-phosphate-3-epimerase; pentose-5-phosphate-3-epimerase 1862850 9728007 SPAP_1993 Streptococcus pneumoniae AP200 pentose-5-phosphate-3-epimerase YP_003877557.1 1862194 R 574093 CDS YP_003877558.1 307068592 9728008 complement(1862861..1863739) 1 NC_014494.1 Operon 889 Gene 5 COG1162 Predicted GTPases; putative GTPase 1863739 9728008 SPAP_1994 Streptococcus pneumoniae AP200 putative GTPase YP_003877558.1 1862861 R 574093 CDS YP_003877559.1 307068593 9728009 complement(1863741..1864613) 1 NC_014494.1 Operon 889 Gene 6 COG0030 Dimethyladenosine transferase (rRNA methylation); dimethyladenosine transferase 1864613 9728009 SPAP_1995 Streptococcus pneumoniae AP200 dimethyladenosine transferase YP_003877559.1 1863741 R 574093 CDS YP_003877560.1 307068594 9728010 complement(1864744..1865052) 1 NC_014494.1 Operon 890 Gene 1 protein supported gi|111658872|ref|ZP_01409493.1| hypothetical protein SpneT_02000043; hypothetical protein 1865052 9728010 SPAP_1996 Streptococcus pneumoniae AP200 hypothetical protein YP_003877560.1 1864744 R 574093 CDS YP_003877561.1 307068595 9728011 complement(1865045..1865686) 1 NC_014494.1 Operon 890 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1865686 9728011 SPAP_1997 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter ATPase YP_003877561.1 1865045 R 574093 CDS YP_003877562.1 307068596 9728012 complement(1865688..1867718) 1 NC_014494.1 Operon 890 Gene 3 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 1867718 9728012 SPAP_1998 Streptococcus pneumoniae AP200 hypothetical protein YP_003877562.1 1865688 R 574093 CDS YP_003877563.1 307068597 9728013 complement(1867795..1868091) 1 NC_014494.1 Operon 890 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1868091 9728013 SPAP_1999 Streptococcus pneumoniae AP200 hypothetical protein YP_003877563.1 1867795 R 574093 CDS YP_003877564.1 307068598 9728014 complement(1868564..1868938) 1 NC_014494.1 Operon 891 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 1868938 9728014 SPAP_2000 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877564.1 1868564 R 574093 CDS YP_003877565.1 307068599 9728015 complement(1868950..1870197) 1 NC_014494.1 transposase-like protein, IS1515 1870197 9728015 SPAP_2001 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877565.1 1868950 R 574093 CDS YP_003877566.1 307068600 9728016 complement(1870269..1870829) 1 NC_014494.1 Operon 891 Gene 3 COG1658 Small primase-like proteins (Toprim domain); small primase-like protein 1870829 9728016 SPAP_2002 Streptococcus pneumoniae AP200 small primase-like protein YP_003877566.1 1870269 R 574093 CDS YP_003877567.1 307068601 9728017 complement(1870829..1871602) 1 NC_014494.1 Operon 891 Gene 4 COG0084 Mg-dependent DNase; Mg-dependent DNase 1871602 9728017 SPAP_2003 Streptococcus pneumoniae AP200 Mg-dependent DNase YP_003877567.1 1870829 R 574093 CDS YP_003877568.1 307068602 9728018 complement(1871907..1872572) 1 NC_014494.1 cell wall surface anchor family protein; hypothetical protein 1872572 9728018 SPAP_2004 Streptococcus pneumoniae AP200 hypothetical protein YP_003877568.1 1871907 R 574093 CDS YP_003877569.1 307068603 9728019 complement(1872835..1872969) 1 NC_014494.1 Operon 893 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1872969 9728019 SPAP_2005 Streptococcus pneumoniae AP200 hypothetical protein YP_003877569.1 1872835 R 574093 CDS YP_003877570.1 307068604 9728020 complement(1873114..1874328) 1 NC_014494.1 Operon 894 Gene 1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase 1874328 9728020 SPAP_2006 Streptococcus pneumoniae AP200 aspartate/tyrosine/aromatic aminotransferase YP_003877570.1 1873114 R 574093 CDS YP_003877571.1 307068605 9728021 complement(1874484..1874774) 1 NC_014494.1 Operon 894 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1874774 9728021 SPAP_2007 Streptococcus pneumoniae AP200 hypothetical protein YP_003877571.1 1874484 R 574093 CDS YP_003877572.1 307068606 9728022 1874939..1875391 1 NC_014494.1 Operon 895 Gene 1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein UspA-like nucleotide-binding protein 1875391 9728022 SPAP_2008 Streptococcus pneumoniae AP200 Universal stress protein UspA-like nucleotide-binding protein YP_003877572.1 1874939 D 574093 CDS YP_003877573.1 307068607 9728023 complement(1875426..1876814) 1 NC_014494.1 Operon 896 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1876814 9728023 SPAP_2009 Streptococcus pneumoniae AP200 putative HAD superfamily hydrolase YP_003877573.1 1875426 R 574093 CDS YP_003877574.1 307068608 9728024 1876880..1877842 1 NC_014494.1 Operon 897 Gene 1 COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D 1877842 9728024 SPAP_2010 Streptococcus pneumoniae AP200 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D YP_003877574.1 1876880 D 574093 CDS YP_003877575.1 307068609 9728025 complement(1878138..1879148) 1 NC_014494.1 Operon 898 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator 1879148 9728025 SPAP_2011 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877575.1 1878138 R 574093 CDS YP_003877576.1 307068610 9728026 complement(1879573..1880172) 1 NC_014494.1 Operon 899 Gene 1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; CheY-like receiver/HTH DNA-binding domain-containing response regulator 1880172 9728026 SPAP_2012 Streptococcus pneumoniae AP200 CheY-like receiver/HTH DNA-binding domain-containing response regulator YP_003877576.1 1879573 R 574093 CDS YP_003877577.1 307068611 9728027 complement(1880174..1881241) 1 NC_014494.1 Operon 899 Gene 2 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 1881241 9728027 SPAP_2013 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003877577.1 1880174 R 574093 CDS YP_003877578.1 307068612 9728028 complement(1881271..1882008) 1 NC_014494.1 Operon 899 Gene 3 COG0842 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease 1882008 9728028 SPAP_2014 Streptococcus pneumoniae AP200 multidrug ABC transporter permease YP_003877578.1 1881271 R 574093 CDS YP_003877579.1 307068613 9728029 complement(1882010..1882894) 1 NC_014494.1 Operon 899 Gene 4 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1882894 9728029 SPAP_2015 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase YP_003877579.1 1882010 R 574093 CDS YP_003877580.1 307068614 9728030 complement(1882881..1883075) 1 NC_014494.1 Operon 899 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 1883075 9728030 SPAP_2016 Streptococcus pneumoniae AP200 hypothetical protein YP_003877580.1 1882881 R 574093 CDS YP_003877581.1 307068615 9728031 complement(1883072..1883251) 1 NC_014494.1 Operon 899 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 1883251 9728031 SPAP_2017 Streptococcus pneumoniae AP200 hypothetical protein YP_003877581.1 1883072 R 574093 CDS YP_003877582.1 307068616 9728045 complement(1889968..1890345) 1 NC_014494.1 transposase-like protein, IS1239 1890345 9728045 SPAP_2031 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877582.1 1889968 R 574093 CDS YP_003877583.1 307068617 9728046 complement(1890381..1890923) 1 NC_014494.1 transposase-like protein, IS1239 1890923 9728046 SPAP_2032 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877583.1 1890381 R 574093 CDS YP_003877584.1 307068618 9728047 complement(1891211..1891690) 1 NC_014494.1 Operon 901 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1891690 9728047 SPAP_2033 Streptococcus pneumoniae AP200 hypothetical protein YP_003877584.1 1891211 R 574093 CDS YP_003877585.1 307068619 9728048 complement(1891812..1892348) 1 NC_014494.1 Operon 902 Gene 1 COG0250 Transcription antiterminator; transcription antiterminator 1892348 9728048 SPAP_2034 Streptococcus pneumoniae AP200 transcription antiterminator YP_003877585.1 1891812 R 574093 CDS YP_003877586.1 307068620 9728049 complement(1892403..1892579) 1 NC_014494.1 Operon 902 Gene 2 COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE 1892579 9728049 SPAP_2035 Streptococcus pneumoniae AP200 preprotein translocase subunit SecE YP_003877586.1 1892403 R 574093 CDS YP_003877587.1 307068621 9728050 1892491..1892691 1 NC_014494.1 Operon 903 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1892691 9728050 SPAP_2036 Streptococcus pneumoniae AP200 hypothetical protein YP_003877587.1 1892491 D 574093 CDS YP_003877588.1 307068622 9728051 complement(1892589..1892741) 1 NC_014494.1 Operon 904 Gene 1 protein supported gi|15903864|ref|NP_359414.1| 50S ribosomal protein L33; hypothetical protein 1892741 9728051 SPAP_2037 Streptococcus pneumoniae AP200 hypothetical protein YP_003877588.1 1892589 R 574093 CDS YP_003877589.1 307068623 9728052 complement(1892794..1894989) 1 NC_014494.1 Operon 904 Gene 2 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase 1894989 9728052 SPAP_2038 Streptococcus pneumoniae AP200 membrane carboxypeptidase YP_003877589.1 1892794 R 574093 CDS YP_003877590.1 307068624 9728053 1895076..1895951 1 NC_014494.1 Operon 905 Gene 1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 1895951 9728053 SPAP_2039 Streptococcus pneumoniae AP200 23S RNA-specific pseudouridylate synthase YP_003877590.1 1895076 D 574093 CDS YP_003877591.1 307068625 9728054 complement(1896018..1897025) 1 NC_014494.1 Operon 906 Gene 1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 1897025 9728054 SPAP_2040 Streptococcus pneumoniae AP200 glyceraldehyde-3-phosphate dehydrogenase YP_003877591.1 1896018 R 574093 CDS YP_003877592.1 307068626 9728055 complement(1897202..1898164) 1 NC_014494.1 Operon 907 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 1898164 9728055 SPAP_2041 Streptococcus pneumoniae AP200 antimicrobial peptide ABC transporter permease YP_003877592.1 1897202 R 574093 CDS YP_003877593.1 307068627 9728056 complement(1898225..1898407) 1 NC_014494.1 Operon 907 Gene 2 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 1898407 9728056 SPAP_2042 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003877593.1 1898225 R 574093 CDS YP_003877594.1 307068628 9728057 complement(1898723..1899088) 1 NC_014494.1 transposase-like protein, IS630 1899088 9728057 SPAP_2043 Streptococcus pneumoniae AP200 transposase-like protein, IS630 YP_003877594.1 1898723 R 574093 CDS YP_003877595.1 307068629 9728058 complement(1899201..1900073) 1 NC_014494.1 Operon 909 Gene 1 COG0157 Nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase 1900073 9728058 SPAP_2044 Streptococcus pneumoniae AP200 nicotinate-nucleotide pyrophosphorylase YP_003877595.1 1899201 R 574093 CDS YP_003877596.1 307068630 9728059 1900310..1901620 1 NC_014494.1 Operon 910 Gene 1 COG0471 Di- and tricarboxylate transporters; di- and tricarboxylate transporter 1901620 9728059 SPAP_2045 Streptococcus pneumoniae AP200 di- and tricarboxylate transporter YP_003877596.1 1900310 D 574093 CDS YP_003877597.1 307068631 9728060 complement(1901991..1902185) 1 NC_014494.1 Operon 911 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1902185 9728060 SPAP_2046 Streptococcus pneumoniae AP200 hypothetical protein YP_003877597.1 1901991 R 574093 CDS YP_003877598.1 307068632 9728061 complement(1902645..1903373) 1 NC_014494.1 Operon 912 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 1903373 9728061 SPAP_2047 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877598.1 1902645 R 574093 CDS YP_003877599.1 307068633 9728062 1903531..1904940 1 NC_014494.1 Operon 913 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 1904940 9728062 SPAP_2048 Streptococcus pneumoniae AP200 beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase YP_003877599.1 1903531 D 574093 CDS YP_003877600.1 307068634 9728063 1904958..1906253 1 NC_014494.1 Operon 913 Gene 2 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1906253 9728063 SPAP_2049 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIC YP_003877600.1 1904958 D 574093 CDS YP_003877601.1 307068635 9728064 1906258..1906566 1 NC_014494.1 Operon 913 Gene 3 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 1906566 9728064 SPAP_2050 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIB YP_003877601.1 1906258 D 574093 CDS YP_003877602.1 307068636 9728065 1906563..1906871 1 NC_014494.1 Operon 913 Gene 4 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 1906871 9728065 SPAP_2051 Streptococcus pneumoniae AP200 PTS system cellobiose-specific transporter subunit IIA YP_003877602.1 1906563 D 574093 CDS YP_003877603.1 307068637 9728066 complement(1907738..1910410) 1 NC_014494.1 Operon 914 Gene 1 COG1012 NAD-dependent aldehyde dehydrogenases; NAD-dependent aldehyde dehydrogenase 1910410 9728066 SPAP_2052 Streptococcus pneumoniae AP200 NAD-dependent aldehyde dehydrogenase YP_003877603.1 1907738 R 574093 CDS YP_003877604.1 307068638 9728067 complement(1910689..1911099) 1 NC_014494.1 Operon 915 Gene 1 COG4642 Uncharacterized protein conserved in bacteria; hypothetical protein 1911099 9728067 SPAP_2053 Streptococcus pneumoniae AP200 hypothetical protein YP_003877604.1 1910689 R 574093 CDS YP_003877605.1 307068639 9728068 complement(1911101..1911529) 1 NC_014494.1 Operon 915 Gene 2 COG0394 Protein-tyrosine-phosphatase; protein-tyrosine-phosphatase 1911529 9728068 SPAP_2054 Streptococcus pneumoniae AP200 protein-tyrosine-phosphatase YP_003877605.1 1911101 R 574093 CDS YP_003877606.1 307068640 9728069 complement(1911575..1911874) 1 NC_014494.1 Operon 915 Gene 3 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC 1911874 9728069 SPAP_2055 Streptococcus pneumoniae AP200 preprotein translocase subunit YajC YP_003877606.1 1911575 R 574093 CDS YP_003877607.1 307068641 9728070 complement(1911991..1913967) 1 NC_014494.1 Operon 916 Gene 1 COG0021 Transketolase; transketolase 1913967 9728070 SPAP_2056 Streptococcus pneumoniae AP200 transketolase YP_003877607.1 1911991 R 574093 CDS YP_003877608.1 307068642 9728071 complement(1914080..1915171) 1 NC_014494.1 Operon 917 Gene 1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; putative Zn-dependent hydrolase 1915171 9728071 SPAP_2057 Streptococcus pneumoniae AP200 putative Zn-dependent hydrolase YP_003877608.1 1914080 R 574093 CDS YP_003877609.1 307068643 9728072 complement(1915283..1916956) 1 NC_014494.1 Operon 918 Gene 1 COG3711 Transcriptional antiterminator; transcriptional antiterminator 1916956 9728072 SPAP_2058 Streptococcus pneumoniae AP200 transcriptional antiterminator YP_003877609.1 1915283 R 574093 CDS YP_003877610.1 307068644 9728073 complement(1917135..1917839) 1 NC_014494.1 Operon 919 Gene 1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; ribulose-5-phosphate 4-epimerase-like epimerase and aldolase 1917839 9728073 SPAP_2059 Streptococcus pneumoniae AP200 ribulose-5-phosphate 4-epimerase-like epimerase and aldolase YP_003877610.1 1917135 R 574093 CDS YP_003877611.1 307068645 9728074 complement(1917841..1918704) 1 NC_014494.1 Operon 919 Gene 2 COG3623 Putative L-xylulose-5-phosphate 3-epimerase; putative L-xylulose-5-phosphate 3-epimerase 1918704 9728074 SPAP_2060 Streptococcus pneumoniae AP200 putative L-xylulose-5-phosphate 3-epimerase YP_003877611.1 1917841 R 574093 CDS YP_003877612.1 307068646 9728075 complement(1918708..1919373) 1 NC_014494.1 Operon 919 Gene 3 COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-hexulose-6-phosphate synthase-like protein 1919373 9728075 SPAP_2061 Streptococcus pneumoniae AP200 3-hexulose-6-phosphate synthase-like protein YP_003877612.1 1918708 R 574093 CDS YP_003877613.1 307068647 9728076 complement(1919390..1919875) 1 NC_014494.1 Operon 919 Gene 4 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein 1919875 9728076 SPAP_2062 Streptococcus pneumoniae AP200 PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein YP_003877613.1 1919390 R 574093 CDS YP_003877614.1 307068648 9728077 complement(1919952..1920233) 1 NC_014494.1 Operon 919 Gene 5 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 1920233 9728077 SPAP_2063 Streptococcus pneumoniae AP200 PTS system galactitol-specific transporter subunit IIB YP_003877614.1 1919952 R 574093 CDS YP_003877615.1 307068649 9728078 complement(1920256..1921713) 1 NC_014494.1 Operon 919 Gene 6 COG3037 Uncharacterized protein conserved in bacteria; hypothetical protein 1921713 9728078 SPAP_2064 Streptococcus pneumoniae AP200 hypothetical protein YP_003877615.1 1920256 R 574093 CDS YP_003877616.1 307068650 9728079 complement(1921844..1922467) 1 NC_014494.1 Operon 920 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1922467 9728079 SPAP_2065 Streptococcus pneumoniae AP200 hypothetical protein YP_003877616.1 1921844 R 574093 CDS YP_003877617.1 307068651 9728080 complement(1922518..1923504) 1 NC_014494.1 Operon 920 Gene 2 COG1847 Predicted RNA-binding protein; putative RNA-binding protein 1923504 9728080 SPAP_2066 Streptococcus pneumoniae AP200 putative RNA-binding protein YP_003877617.1 1922518 R 574093 CDS YP_003877618.1 307068652 9728081 complement(1923523..1924329) 1 NC_014494.1 Operon 920 Gene 3 COG0706 Preprotein translocase subunit YidC; preprotein translocase subunit YidC 1924329 9728081 SPAP_2067 Streptococcus pneumoniae AP200 preprotein translocase subunit YidC YP_003877618.1 1923523 R 574093 CDS YP_003877619.1 307068653 9728082 complement(1924322..1924693) 1 NC_014494.1 Operon 920 Gene 4 COG0594 RNase P protein component; RNase P protein component 1924693 9728082 SPAP_2068 Streptococcus pneumoniae AP200 RNase P protein component YP_003877619.1 1924322 R 574093 CDS YP_003877620.1 307068654 9728083 complement(1924842..1926032) 1 NC_014494.1 Operon 921 Gene 1 COG0282 Acetate kinase; acetate kinase 1926032 9728083 SPAP_2069 Streptococcus pneumoniae AP200 acetate kinase YP_003877620.1 1924842 R 574093 CDS YP_003877621.1 307068655 9728084 complement(1926083..1927036) 1 NC_014494.1 Operon 921 Gene 2 COG0827 Adenine-specific DNA methylase; adenine-specific DNa methylase 1927036 9728084 SPAP_2070 Streptococcus pneumoniae AP200 adenine-specific DNa methylase YP_003877621.1 1926083 R 574093 CDS YP_003877622.1 307068656 9728085 complement(1927097..1927477) 1 NC_014494.1 Operon 921 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1927477 9728085 SPAP_2071 Streptococcus pneumoniae AP200 hypothetical protein YP_003877622.1 1927097 R 574093 CDS YP_003877623.1 307068657 9728086 complement(1927509..1927691) 1 NC_014494.1 Operon 921 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1927691 9728086 SPAP_2072 Streptococcus pneumoniae AP200 hypothetical protein YP_003877623.1 1927509 R 574093 CDS YP_003877624.1 307068658 9728087 complement(1927828..1928241) 1 NC_014494.1 Operon 922 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1928241 9728087 SPAP_2073 Streptococcus pneumoniae AP200 hypothetical protein YP_003877624.1 1927828 R 574093 CDS YP_003877625.1 307068659 9728088 complement(1928219..1928680) 1 NC_014494.1 Operon 922 Gene 2 COG4940 Competence protein ComGF; competence protein ComGF 1928680 9728088 SPAP_2074 Streptococcus pneumoniae AP200 competence protein ComGF YP_003877625.1 1928219 R 574093 CDS YP_003877626.1 307068660 9728089 complement(1928643..1928945) 1 NC_014494.1 Operon 922 Gene 3 COG2165 Type II secretory pathway, pseudopilin PulG; type II secretory pathway, pseudopilin PulG 1928945 9728089 SPAP_2075 Streptococcus pneumoniae AP200 type II secretory pathway, pseudopilin PulG YP_003877626.1 1928643 R 574093 CDS YP_003877627.1 307068661 9728090 complement(1928908..1929336) 1 NC_014494.1 Operon 922 Gene 4 COG2165 Type II secretory pathway, pseudopilin PulG; type II secretory pathway, pseudopilin PulG 1929336 9728090 SPAP_2076 Streptococcus pneumoniae AP200 type II secretory pathway, pseudopilin PulG YP_003877627.1 1928908 R 574093 CDS YP_003877628.1 307068662 9728091 complement(1929305..1929631) 1 NC_014494.1 Operon 922 Gene 5 COG4537 Competence protein ComGC; competence protein ComGC 1929631 9728091 SPAP_2077 Streptococcus pneumoniae AP200 competence protein ComGC YP_003877628.1 1929305 R 574093 CDS YP_003877629.1 307068663 9728092 complement(1929633..1930505) 1 NC_014494.1 Operon 922 Gene 6 COG1459 Type II secretory pathway, component PulF; type II secretory pathway, component PulF 1930505 9728092 SPAP_2078 Streptococcus pneumoniae AP200 type II secretory pathway, component PulF YP_003877629.1 1929633 R 574093 CDS YP_003877630.1 307068664 9728093 complement(1930597..1931538) 1 NC_014494.1 Operon 922 Gene 7 COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; type II secretory pathway, ATPase PulE/tfp pilus assembly pathway ATPase PilB 1931538 9728093 SPAP_2079 Streptococcus pneumoniae AP200 type II secretory pathway, ATPase PulE/tfp pilus assembly pathway ATPase PilB YP_003877630.1 1930597 R 574093 CDS YP_003877631.1 307068665 9728094 complement(1931614..1931799) 1 NC_014494.1 Operon 922 Gene 8 COG4699 Uncharacterized protein conserved in bacteria; hypothetical protein 1931799 9728094 SPAP_2080 Streptococcus pneumoniae AP200 hypothetical protein YP_003877631.1 1931614 R 574093 CDS YP_003877632.1 307068666 9728095 complement(1932130..1933188) 1 NC_014494.1 Operon 923 Gene 1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase 1933188 9728095 SPAP_2081 Streptococcus pneumoniae AP200 threonine dehydrogenase-like Zn-dependent dehydrogenase YP_003877632.1 1932130 R 574093 CDS YP_003877633.1 307068667 9728096 complement(1933351..1934502) 1 NC_014494.1 Operon 924 Gene 1 COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 1934502 9728096 SPAP_2082 Streptococcus pneumoniae AP200 N-acetylglucosamine-6-phosphate deacetylase YP_003877633.1 1933351 R 574093 CDS YP_003877634.1 307068668 9728097 complement(1934655..1936472) 1 NC_014494.1 Operon 925 Gene 1 COG1835 Predicted acyltransferases; putative acyltransferase 1936472 9728097 SPAP_2083 Streptococcus pneumoniae AP200 putative acyltransferase YP_003877634.1 1934655 R 574093 CDS YP_003877635.1 307068669 9728098 complement(1936573..1937715) 1 NC_014494.1 Operon 926 Gene 1 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; Queuine/archaeosine tRNA-ribosyltransferase 1937715 9728098 SPAP_2084 Streptococcus pneumoniae AP200 Queuine/archaeosine tRNA-ribosyltransferase YP_003877635.1 1936573 R 574093 CDS YP_003877636.1 307068670 9728099 1937845..1938702 1 NC_014494.1 Operon 927 Gene 1 COG5523 Predicted integral membrane protein; putative integral membrane protein 1938702 9728099 SPAP_2085 Streptococcus pneumoniae AP200 putative integral membrane protein YP_003877636.1 1937845 D 574093 CDS YP_003877637.1 307068671 9728100 complement(1938730..1939374) 1 NC_014494.1 Operon 928 Gene 1 COG2039; N-terminal pyroglutamyl peptidase; pyrrolidone-carboxylate peptidase 1939374 9728100 SPAP_2086 Streptococcus pneumoniae AP200 pyrrolidone-carboxylate peptidase YP_003877637.1 1938730 R 574093 CDS YP_003877638.1 307068672 9728101 complement(1939449..1939850) 1 NC_014494.1 Operon 928 Gene 2 COG3759 Predicted membrane protein; hypothetical protein 1939850 9728101 SPAP_2087 Streptococcus pneumoniae AP200 hypothetical protein YP_003877638.1 1939449 R 574093 CDS YP_003877639.1 307068673 9728102 complement(1939861..1940286) 1 NC_014494.1 Operon 928 Gene 3 COG1846 Transcriptional regulators; transcriptional regulator 1940286 9728102 SPAP_2088 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877639.1 1939861 R 574093 CDS YP_003877640.1 307068674 9728103 complement(1940609..1941721) 1 NC_014494.1 Operon 929 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1941721 9728103 SPAP_2089 Streptococcus pneumoniae AP200 hypothetical protein YP_003877640.1 1940609 R 574093 CDS YP_003877641.1 307068675 9728104 complement(1941887..1942507) 1 NC_014494.1 Operon 930 Gene 1 COG0546 Predicted phosphatases; putative phosphatase 1942507 9728104 SPAP_2090 Streptococcus pneumoniae AP200 putative phosphatase YP_003877641.1 1941887 R 574093 CDS YP_003877642.1 307068676 9728105 complement(1942511..1943791) 1 NC_014494.1 Operon 930 Gene 2 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 1943791 9728105 SPAP_2091 Streptococcus pneumoniae AP200 Na+-driven multidrug efflux pump YP_003877642.1 1942511 R 574093 CDS YP_003877643.1 307068677 9728106 complement(1943852..1945336) 1 NC_014494.1 Operon 931 Gene 1 COG0498 Threonine synthase; threonine synthase 1945336 9728106 SPAP_2092 Streptococcus pneumoniae AP200 threonine synthase YP_003877643.1 1943852 R 574093 CDS YP_003877644.1 307068678 9728107 complement(1945412..1945945) 1 NC_014494.1 Operon 931 Gene 2 COG3572 Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase 1945945 9728107 SPAP_2093 Streptococcus pneumoniae AP200 gamma-glutamylcysteine synthetase YP_003877644.1 1945412 R 574093 CDS YP_003877645.1 307068679 9728108 1945919..1946344 1 NC_014494.1 transposase-like protein, IS1515 1946344 9728108 SPAP_2094 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877645.1 1945919 D 574093 CDS YP_003877646.1 307068680 9728109 1946356..1946733 1 NC_014494.1 Operon 932 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 1946733 9728109 SPAP_2095 Streptococcus pneumoniae AP200 transposase-like protein, IS1515 YP_003877646.1 1946356 D 574093 CDS YP_003877647.1 307068681 9728110 complement(1946747..1947562) 1 NC_014494.1 Operon 933 Gene 1 COG3572 Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase 1947562 9728110 SPAP_2096 Streptococcus pneumoniae AP200 gamma-glutamylcysteine synthetase YP_003877647.1 1946747 R 574093 CDS YP_003877648.1 307068682 9728127 complement(1954033..1954467) 1 NC_014494.1 Operon 936 Gene 1 COG0295 Cytidine deaminase; cytidine deaminase 1954467 9728127 SPAP_2115 Streptococcus pneumoniae AP200 cytidine deaminase YP_003877648.1 1954033 R 574093 CDS YP_003877649.1 307068683 9728128 complement(1954481..1955941) 1 NC_014494.1 Operon 936 Gene 2 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl- and glutaminyl-tRNA synthetase 1955941 9728128 SPAP_2116 Streptococcus pneumoniae AP200 glutamyl- and glutaminyl-tRNA synthetase YP_003877649.1 1954481 R 574093 CDS YP_003877650.1 307068684 9728129 complement(1956065..1957414) 1 NC_014494.1 Operon 937 Gene 1 COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase 1957414 9728129 SPAP_2117 Streptococcus pneumoniae AP200 glucose-6-phosphate isomerase YP_003877650.1 1956065 R 574093 CDS YP_003877651.1 307068685 9728130 complement(1957584..1958273) 1 NC_014494.1 Operon 938 Gene 1 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase 1958273 9728130 SPAP_2118 Streptococcus pneumoniae AP200 putative glutamine amidotransferase YP_003877651.1 1957584 R 574093 CDS YP_003877652.1 307068686 9728131 complement(1958412..1960178) 1 NC_014494.1 Operon 939 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1960178 9728131 SPAP_2119 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877652.1 1958412 R 574093 CDS YP_003877653.1 307068687 9728132 1960331..1960639 1 NC_014494.1 Operon 940 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1960639 9728132 SPAP_2120 Streptococcus pneumoniae AP200 hypothetical protein YP_003877653.1 1960331 D 574093 CDS YP_003877654.1 307068688 9728133 complement(1960970..1962664) 1 NC_014494.1 Operon 941 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1962664 9728133 SPAP_2121 Streptococcus pneumoniae AP200 multidrug ABC transporter ATPase and permease YP_003877654.1 1960970 R 574093 CDS YP_003877655.1 307068689 9728134 complement(1962811..1965345) 1 NC_014494.1 Operon 942 Gene 1 COG0249 Mismatch repair ATPase (MutS family); mismatch repair ATPase 1965345 9728134 SPAP_2122 Streptococcus pneumoniae AP200 mismatch repair ATPase YP_003877655.1 1962811 R 574093 CDS YP_003877656.1 307068690 9728135 complement(1965396..1965842) 1 NC_014494.1 Operon 942 Gene 2 COG1438 Arginine repressor; arginine repressor 1965842 9728135 SPAP_2123 Streptococcus pneumoniae AP200 arginine repressor YP_003877656.1 1965396 R 574093 CDS YP_003877657.1 307068691 9728136 1965978..1967669 1 NC_014494.1 Operon 943 Gene 1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase 1967669 9728136 SPAP_2124 Streptococcus pneumoniae AP200 arginyl-tRNA synthetase YP_003877657.1 1965978 D 574093 CDS YP_003877658.1 307068692 9728137 complement(1967984..1968448) 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 1968448 9728137 SPAP_2125 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003877658.1 1967984 R 574093 CDS YP_003877659.1 307068693 9728138 1968766..1969014 1 NC_014494.1 Operon 945 Gene 1 COG3542 Uncharacterized conserved protein; hypothetical protein 1969014 9728138 SPAP_2126 Streptococcus pneumoniae AP200 hypothetical protein YP_003877659.1 1968766 D 574093 CDS YP_003877660.1 307068694 9728139 1969098..1969352 1 NC_014494.1 Operon 945 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1969352 9728139 SPAP_2127 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003877660.1 1969098 D 574093 CDS YP_003877661.1 307068695 9728140 1969375..1969806 1 NC_014494.1 Operon 945 Gene 3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1969806 9728140 SPAP_2128 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003877661.1 1969375 D 574093 CDS YP_003877662.1 307068696 9728141 1969807..1971138 1 NC_014494.1 Operon 945 Gene 4 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 1971138 9728141 SPAP_2129 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003877662.1 1969807 D 574093 CDS YP_003877663.1 307068697 9728142 1971305..1972180 1 NC_014494.1 Operon 945 Gene 5 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 1972180 9728142 SPAP_2130 Streptococcus pneumoniae AP200 phosphate ABC transporter substrate-binding protein YP_003877663.1 1971305 D 574093 CDS YP_003877664.1 307068698 9728143 1972346..1973161 1 NC_014494.1 Operon 945 Gene 6 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1973161 9728143 SPAP_2131 Streptococcus pneumoniae AP200 phosphate ABC transporter permease YP_003877664.1 1972346 D 574093 CDS YP_003877665.1 307068699 9728144 1973154..1973969 1 NC_014494.1 Operon 945 Gene 7 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1973969 9728144 SPAP_2132 Streptococcus pneumoniae AP200 phosphate ABC transporter permease YP_003877665.1 1973154 D 574093 CDS YP_003877666.1 307068700 9728145 1973971..1974723 1 NC_014494.1 Operon 945 Gene 8 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase 1974723 9728145 SPAP_2133 Streptococcus pneumoniae AP200 phosphate ABC transporter ATPase YP_003877666.1 1973971 D 574093 CDS YP_003877667.1 307068701 9728146 1974738..1975388 1 NC_014494.1 Operon 945 Gene 9 COG0704 Phosphate uptake regulator; phosphate uptake regulator 1975388 9728146 SPAP_2134 Streptococcus pneumoniae AP200 phosphate uptake regulator YP_003877667.1 1974738 D 574093 CDS YP_003877668.1 307068702 9728147 1975456..1975881 1 NC_014494.1 transposase-like protein, IS1380 ISSpn5 1975881 9728147 SPAP_2135 Streptococcus pneumoniae AP200 transposase-like protein, IS1380 ISSpn5 YP_003877668.1 1975456 D 574093 CDS YP_003877669.1 307068703 9728148 complement(1976055..1976435) 1 NC_014494.1 Operon 947 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1976435 9728148 SPAP_2136 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877669.1 1976055 R 574093 CDS YP_003877670.1 307068704 9728149 1976647..1977663 1 NC_014494.1 Operon 948 Gene 1 COG0240 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1977663 9728149 SPAP_2137 Streptococcus pneumoniae AP200 glycerol-3-phosphate dehydrogenase YP_003877670.1 1976647 D 574093 CDS YP_003877671.1 307068705 9728150 1977685..1978584 1 NC_014494.1 Operon 948 Gene 2 COG1210 UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase 1978584 9728150 SPAP_2138 Streptococcus pneumoniae AP200 UDP-glucose pyrophosphorylase YP_003877671.1 1977685 D 574093 CDS YP_003877672.1 307068706 9728151 complement(1978651..1979328) 1 NC_014494.1 Operon 949 Gene 1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); hypothetical protein 1979328 9728151 SPAP_2139 Streptococcus pneumoniae AP200 hypothetical protein YP_003877672.1 1978651 R 574093 CDS YP_003877673.1 307068707 9728152 complement(1979312..1979851) 1 NC_014494.1 Operon 949 Gene 2 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1979851 9728152 SPAP_2140 Streptococcus pneumoniae AP200 5-formyltetrahydrofolate cyclo-ligase YP_003877673.1 1979312 R 574093 CDS YP_003877674.1 307068708 9728153 complement(1979863..1980993) 1 NC_014494.1 Operon 949 Gene 3 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; metal-dependent amidase/aminoacylase/carboxypeptidase 1980993 9728153 SPAP_2141 Streptococcus pneumoniae AP200 metal-dependent amidase/aminoacylase/carboxypeptidase YP_003877674.1 1979863 R 574093 CDS YP_003877675.1 307068709 9728154 complement(1981061..1981759) 1 NC_014494.1 Operon 949 Gene 4 COG2171 Tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate N-succinyltransferase 1981759 9728154 SPAP_2142 Streptococcus pneumoniae AP200 tetrahydrodipicolinate N-succinyltransferase YP_003877675.1 1981061 R 574093 CDS YP_003877676.1 307068710 9728155 complement(1981989..1983104) 1 NC_014494.1 Operon 950 Gene 1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease 1983104 9728155 SPAP_2143 Streptococcus pneumoniae AP200 drug/metabolite transporter (DMT) superfamily permease YP_003877676.1 1981989 R 574093 CDS YP_003877677.1 307068711 9728156 complement(1982965..1985430) 1 NC_014494.1 Operon 950 Gene 2 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase 1985430 9728156 SPAP_2144 Streptococcus pneumoniae AP200 membrane carboxypeptidase YP_003877677.1 1982965 R 574093 CDS YP_003877678.1 307068712 9728157 1985572..1986828 1 NC_014494.1 Operon 951 Gene 1 COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 1986828 9728157 SPAP_2145 Streptococcus pneumoniae AP200 tyrosyl-tRNA synthetase YP_003877678.1 1985572 D 574093 CDS YP_003877679.1 307068713 9728158 complement(1986906..1988969) 1 NC_014494.1 Operon 952 Gene 1 COG2217 Cation transport ATPase; cation transport ATPase 1988969 9728158 SPAP_2146 Streptococcus pneumoniae AP200 cation transport ATPase YP_003877679.1 1986906 R 574093 CDS YP_003877680.1 307068714 9728159 complement(1988971..1989249) 1 NC_014494.1 Operon 952 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1989249 9728159 SPAP_2147 Streptococcus pneumoniae AP200 hypothetical protein YP_003877680.1 1988971 R 574093 CDS YP_003877681.1 307068715 9728160 1989401..1990249 1 NC_014494.1 Operon 953 Gene 1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 1990249 9728160 SPAP_2148 Streptococcus pneumoniae AP200 SAM-dependent methyltransferase YP_003877681.1 1989401 D 574093 CDS YP_003877682.1 307068716 9728161 complement(1990363..1990533) 1 NC_014494.1 Operon 954 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1990533 9728161 SPAP_2149 Streptococcus pneumoniae AP200 hypothetical protein YP_003877682.1 1990363 R 574093 CDS YP_003877683.1 307068717 9728162 1990870..1991442 1 NC_014494.1 Operon 955 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1991442 9728162 SPAP_2150 Streptococcus pneumoniae AP200 hypothetical protein YP_003877683.1 1990870 D 574093 CDS YP_003877684.1 307068718 9728163 complement(1991432..1991572) 1 NC_014494.1 Operon 956 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1991572 9728163 SPAP_2151 Streptococcus pneumoniae AP200 hypothetical protein YP_003877684.1 1991432 R 574093 CDS YP_003877685.1 307068719 9728164 1991609..1991809 1 NC_014494.1 Operon 957 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1991809 9728164 SPAP_2152 Streptococcus pneumoniae AP200 hypothetical protein YP_003877685.1 1991609 D 574093 CDS YP_003877686.1 307068720 9728165 complement(1991983..1992129) 1 NC_014494.1 Operon 958 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1992129 9728165 SPAP_2153 Streptococcus pneumoniae AP200 hypothetical protein YP_003877686.1 1991983 R 574093 CDS YP_003877687.1 307068721 9728166 complement(1992487..1994745) 1 NC_014494.1 Operon 959 Gene 1 COG0058 Glucan phosphorylase; glucan phosphorylase 1994745 9728166 SPAP_2154 Streptococcus pneumoniae AP200 glucan phosphorylase YP_003877687.1 1992487 R 574093 CDS YP_003877688.1 307068722 9728167 complement(1994771..1996288) 1 NC_014494.1 Operon 959 Gene 2 COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 1996288 9728167 SPAP_2155 Streptococcus pneumoniae AP200 4-alpha-glucanotransferase YP_003877688.1 1994771 R 574093 CDS YP_003877689.1 307068723 9728168 1996838..1998109 1 NC_014494.1 Operon 960 Gene 1 COG2182 Maltose-binding periplasmic proteins/domains; maltose-binding periplasmic protein 1998109 9728168 SPAP_2156 Streptococcus pneumoniae AP200 maltose-binding periplasmic protein YP_003877689.1 1996838 D 574093 CDS YP_003877690.1 307068724 9728169 1998205..1998948 1 NC_014494.1 Operon 960 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1998948 9728169 SPAP_2157 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877690.1 1998205 D 574093 CDS YP_003877691.1 307068725 9728170 1998960..1999511 1 NC_014494.1 Operon 960 Gene 3 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1999511 9728170 SPAP_2158 Streptococcus pneumoniae AP200 sugar ABC transporter permease YP_003877691.1 1998960 D 574093 CDS YP_003877692.1 307068726 9728171 1999513..2000355 1 NC_014494.1 Operon 960 Gene 4 COG3833 ABC-type maltose transport systems, permease component; maltose ABC transporter permease 2000355 9728171 SPAP_2159 Streptococcus pneumoniae AP200 maltose ABC transporter permease YP_003877692.1 1999513 D 574093 CDS YP_003877693.1 307068727 9728172 2000608..2001408 1 NC_014494.1 Operon 961 Gene 1 COG5521 Predicted integral membrane protein; putative integral membrane protein 2001408 9728172 SPAP_2160 Streptococcus pneumoniae AP200 putative integral membrane protein YP_003877693.1 2000608 D 574093 CDS YP_003877694.1 307068728 9728173 2001418..2002404 1 NC_014494.1 Operon 961 Gene 2 COG1609 Transcriptional regulators; transcriptional regulator 2002404 9728173 SPAP_2161 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877694.1 2001418 D 574093 CDS YP_003877695.1 307068729 9728174 complement(2002740..2003681) 1 NC_014494.1 Operon 962 Gene 1 COG1284 Uncharacterized conserved protein; hypothetical protein 2003681 9728174 SPAP_2162 Streptococcus pneumoniae AP200 hypothetical protein YP_003877695.1 2002740 R 574093 CDS YP_003877696.1 307068730 9728175 complement(2003659..2005422) 1 NC_014494.1 Operon 962 Gene 2 COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase 2005422 9728175 SPAP_2163 Streptococcus pneumoniae AP200 aspartyl-tRNA synthetase YP_003877696.1 2003659 R 574093 CDS YP_003877697.1 307068731 9728176 complement(2005541..2005732) 1 NC_014494.1 Operon 963 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2005732 9728176 SPAP_2164 Streptococcus pneumoniae AP200 hypothetical protein YP_003877697.1 2005541 R 574093 CDS YP_003877698.1 307068732 9728177 complement(2005774..2006004) 1 NC_014494.1 Operon 963 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 2006004 9728177 SPAP_2165 Streptococcus pneumoniae AP200 hypothetical protein YP_003877698.1 2005774 R 574093 CDS YP_003877699.1 307068733 9728178 complement(2006022..2006663) 1 NC_014494.1 Operon 963 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 2006663 9728178 SPAP_2166 Streptococcus pneumoniae AP200 putative metal-dependent membrane protease YP_003877699.1 2006022 R 574093 CDS YP_003877700.1 307068734 9728179 complement(2006675..2007409) 1 NC_014494.1 Operon 963 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 2007409 9728179 SPAP_2167 Streptococcus pneumoniae AP200 hypothetical protein YP_003877700.1 2006675 R 574093 CDS YP_003877701.1 307068735 9728180 complement(2007412..2007609) 1 NC_014494.1 Operon 963 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 2007609 9728180 SPAP_2168 Streptococcus pneumoniae AP200 hypothetical protein YP_003877701.1 2007412 R 574093 CDS YP_003877702.1 307068736 9728181 complement(2007609..2007815) 1 NC_014494.1 Operon 963 Gene 6 COG1476 Predicted transcriptional regulators; putative transcriptional regulator 2007815 9728181 SPAP_2169 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877702.1 2007609 R 574093 CDS YP_003877703.1 307068737 9728182 complement(2007825..2008139) 1 NC_014494.1 Operon 963 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 2008139 9728182 SPAP_2170 Streptococcus pneumoniae AP200 hypothetical protein YP_003877703.1 2007825 R 574093 CDS YP_003877704.1 307068738 9728183 complement(2008435..2009724) 1 NC_014494.1 Operon 964 Gene 1 COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase 2009724 9728183 SPAP_2171 Streptococcus pneumoniae AP200 histidyl-tRNA synthetase YP_003877704.1 2008435 R 574093 CDS YP_003877705.1 307068739 9728184 complement(2009802..2011049) 1 NC_014494.1 Operon 964 Gene 2 protein supported gi|148990506|ref|ZP_01821647.1| ribosomal protein L11 methyltransferase; hypothetical protein 2011049 9728184 SPAP_2172 Streptococcus pneumoniae AP200 hypothetical protein YP_003877705.1 2009802 R 574093 CDS YP_003877706.1 307068740 9728185 complement(2011239..2012090) 1 NC_014494.1 Operon 965 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 2012090 9728185 SPAP_2173 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877706.1 2011239 R 574093 CDS YP_003877707.1 307068741 9728186 2012214..2012555 1 NC_014494.1 Operon 966 Gene 1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; putative metal-sulfur cluster biosynthetic enzyme 2012555 9728186 SPAP_2174 Streptococcus pneumoniae AP200 putative metal-sulfur cluster biosynthetic enzyme YP_003877707.1 2012214 D 574093 CDS YP_003877708.1 307068742 9728187 2012682..2012873 1 NC_014494.1 Operon 967 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2012873 9728187 SPAP_2175 Streptococcus pneumoniae AP200 hypothetical protein YP_003877708.1 2012682 D 574093 CDS YP_003877709.1 307068743 9728188 complement(2012899..2014602) 1 NC_014494.1 Operon 968 Gene 1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxyacid dehydratase/phosphogluconate dehydratase 2014602 9728188 SPAP_2176 Streptococcus pneumoniae AP200 dihydroxyacid dehydratase/phosphogluconate dehydratase YP_003877709.1 2012899 R 574093 CDS YP_003877710.1 307068744 9728189 complement(2014835..2015764) 1 NC_014494.1 Operon 969 Gene 1 COG3958 Transketolase, C-terminal subunit; transketolase 2015764 9728189 SPAP_2177 Streptococcus pneumoniae AP200 transketolase YP_003877710.1 2014835 R 574093 CDS YP_003877711.1 307068745 9728190 complement(2015764..2016621) 1 NC_014494.1 Operon 969 Gene 2 COG3959 Transketolase, N-terminal subunit; transketolase 2016621 9728190 SPAP_2178 Streptococcus pneumoniae AP200 transketolase YP_003877711.1 2015764 R 574093 CDS YP_003877712.1 307068746 9728191 complement(2016625..2017971) 1 NC_014494.1 Operon 969 Gene 3 COG3037 Uncharacterized protein conserved in bacteria; hypothetical protein 2017971 9728191 SPAP_2179 Streptococcus pneumoniae AP200 hypothetical protein YP_003877712.1 2016625 R 574093 CDS YP_003877713.1 307068747 9728192 complement(2017984..2018268) 1 NC_014494.1 Operon 969 Gene 4 protein supported gi|15901944|ref|NP_346548.1| PTS system, IIB component, putative; hypothetical protein 2018268 9728192 SPAP_2180 Streptococcus pneumoniae AP200 hypothetical protein YP_003877713.1 2017984 R 574093 CDS YP_003877714.1 307068748 9728193 complement(2018272..2020302) 1 NC_014494.1 Operon 969 Gene 5 COG3711 Transcriptional antiterminator; transcriptional antiterminator 2020302 9728193 SPAP_2181 Streptococcus pneumoniae AP200 transcriptional antiterminator YP_003877714.1 2018272 R 574093 CDS YP_003877715.1 307068749 9728194 2020493..2021500 1 NC_014494.1 Operon 970 Gene 1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit 2021500 9728194 SPAP_2182 Streptococcus pneumoniae AP200 membrane protease subunit YP_003877715.1 2020493 D 574093 CDS YP_003877716.1 307068750 9728195 2021503..2021703 1 NC_014494.1 Operon 970 Gene 2 COG4877 Uncharacterized protein conserved in bacteria; hypothetical protein 2021703 9728195 SPAP_2183 Streptococcus pneumoniae AP200 hypothetical protein YP_003877716.1 2021503 D 574093 CDS YP_003877717.1 307068751 9728196 2021854..2022036 1 NC_014494.1 Operon 971 Gene 1 protein supported gi|15901948|ref|NP_346552.1| 50S ribosomal protein L32; hypothetical protein 2022036 9728196 SPAP_2184 Streptococcus pneumoniae AP200 hypothetical protein YP_003877717.1 2021854 D 574093 CDS YP_003877718.1 307068752 9728197 2022052..2022201 1 NC_014494.1 Operon 971 Gene 2 protein supported gi|15901949|ref|NP_346553.1| 50S ribosomal protein L33; hypothetical protein 2022201 9728197 SPAP_2185 Streptococcus pneumoniae AP200 hypothetical protein YP_003877718.1 2022052 D 574093 CDS YP_003877719.1 307068753 9728198 complement(2022694..2024259) 1 NC_014494.1 Operon 972 Gene 1 COG5263 FOG: Choline binding protein PcpA; choline binding protein PcpA 2024259 9728198 SPAP_2186 Streptococcus pneumoniae AP200 choline binding protein PcpA YP_003877719.1 2022694 R 574093 CDS YP_003877720.1 307068754 9728199 2024594..2024776 1 NC_014494.1 Operon 973 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2024776 9728199 SPAP_2187 Streptococcus pneumoniae AP200 hypothetical protein YP_003877720.1 2024594 D 574093 CDS YP_003877721.1 307068755 9728200 2024721..2025107 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 2025107 9728200 SPAP_2188 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003877721.1 2024721 D 574093 CDS YP_003877722.1 307068756 9728201 2025124..2025423 1 NC_014494.1 transposase-like protein, IS1381 ISSpn7 2025423 9728201 SPAP_2189 Streptococcus pneumoniae AP200 transposase-like protein, IS1381 ISSpn7 YP_003877722.1 2025124 D 574093 CDS YP_003877723.1 307068757 9728202 complement(2025495..2025821) 1 NC_014494.1 Operon 974 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2025821 9728202 SPAP_2190 Streptococcus pneumoniae AP200 hypothetical protein YP_003877723.1 2025495 R 574093 CDS YP_003877724.1 307068758 9728203 complement(2026148..2028028) 1 NC_014494.1 Operon 975 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2028028 9728203 SPAP_2191 Streptococcus pneumoniae AP200 hypothetical protein YP_003877724.1 2026148 R 574093 CDS YP_003877725.1 307068759 9728204 complement(2028022..2028891) 1 NC_014494.1 Operon 975 Gene 2 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 2028891 9728204 SPAP_2192 Streptococcus pneumoniae AP200 transcriptional regulator/sugar kinase YP_003877725.1 2028022 R 574093 CDS YP_003877726.1 307068760 9728205 complement(2028975..2031620) 1 NC_014494.1 Operon 975 Gene 3 COG0383 Alpha-mannosidase; alpha-mannosidase 2031620 9728205 SPAP_2193 Streptococcus pneumoniae AP200 alpha-mannosidase YP_003877726.1 2028975 R 574093 CDS YP_003877727.1 307068761 9728206 complement(2031711..2032991) 1 NC_014494.1 Operon 975 Gene 4 COG3538 Uncharacterized conserved protein; hypothetical protein 2032991 9728206 SPAP_2194 Streptococcus pneumoniae AP200 hypothetical protein YP_003877727.1 2031711 R 574093 CDS YP_003877728.1 307068762 9728207 2033162..2035246 1 NC_014494.1 Operon 976 Gene 1 COG3537 Putative alpha-1,2-mannosidase; putative alpha-1,2-mannosidase 2035246 9728207 SPAP_2195 Streptococcus pneumoniae AP200 putative alpha-1,2-mannosidase YP_003877728.1 2033162 D 574093 CDS YP_003877729.1 307068763 9728208 complement(2035286..2036965) 1 NC_014494.1 Operon 977 Gene 1 COG3669 Alpha-L-fucosidase; alpha-L-fucosidase 2036965 9728208 SPAP_2196 Streptococcus pneumoniae AP200 alpha-L-fucosidase YP_003877729.1 2035286 R 574093 CDS YP_003877730.1 307068764 9728209 2037720..2038949 1 NC_014494.1 Operon 978 Gene 1 protein supported gi|148984445|ref|ZP_01817733.1| 50S ribosomal protein L33; hypothetical protein 2038949 9728209 SPAP_2197 Streptococcus pneumoniae AP200 hypothetical protein YP_003877730.1 2037720 D 574093 CDS YP_003877731.1 307068765 9728210 2039007..2040023 1 NC_014494.1 Operon 978 Gene 2 COG0078 Ornithine carbamoyltransferase; ornithine carbamoyltransferase 2040023 9728210 SPAP_2198 Streptococcus pneumoniae AP200 ornithine carbamoyltransferase YP_003877731.1 2039007 D 574093 CDS YP_003877732.1 307068766 9728211 2040188..2041135 1 NC_014494.1 Operon 978 Gene 3 COG0549 Carbamate kinase; carbamate kinase 2041135 9728211 SPAP_2199 Streptococcus pneumoniae AP200 carbamate kinase YP_003877732.1 2040188 D 574093 CDS YP_003877733.1 307068767 9728212 2041344..2042855 1 NC_014494.1 Operon 979 Gene 1 COG1288 Predicted membrane protein; hypothetical protein 2042855 9728212 SPAP_2200 Streptococcus pneumoniae AP200 hypothetical protein YP_003877733.1 2041344 D 574093 CDS YP_003877734.1 307068768 9728213 2042877..2044208 1 NC_014494.1 Operon 979 Gene 2 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 2044208 9728213 SPAP_2201 Streptococcus pneumoniae AP200 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases YP_003877734.1 2042877 D 574093 CDS YP_003877735.1 307068769 9728214 complement(2044613..2044777) 1 NC_014494.1 Operon 980 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2044777 9728214 SPAP_2202 Streptococcus pneumoniae AP200 hypothetical protein YP_003877735.1 2044613 R 574093 CDS YP_003877736.1 307068770 9728215 complement(2044749..2044904) 1 NC_014494.1 Operon 980 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 2044904 9728215 SPAP_2203 Streptococcus pneumoniae AP200 hypothetical protein YP_003877736.1 2044749 R 574093 CDS YP_003877737.1 307068771 9728216 complement(2044892..2045155) 1 NC_014494.1 Operon 980 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 2045155 9728216 SPAP_2204 Streptococcus pneumoniae AP200 hypothetical protein YP_003877737.1 2044892 R 574093 CDS YP_003877738.1 307068772 9728217 complement(2045542..2046441) 1 NC_014494.1 Operon 981 Gene 1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit 2046441 9728217 SPAP_2205 Streptococcus pneumoniae AP200 membrane protease subunit YP_003877738.1 2045542 R 574093 CDS YP_003877739.1 307068773 9728218 complement(2046571..2047722) 1 NC_014494.1 Operon 982 Gene 1 COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase 2047722 9728218 SPAP_2206 Streptococcus pneumoniae AP200 alcohol dehydrogenase YP_003877739.1 2046571 R 574093 CDS YP_003877740.1 307068774 9728219 complement(2047868..2049634) 1 NC_014494.1 Operon 983 Gene 1 COG2407 L-fucose isomerase and related proteins; L-fucose isomerase-like protein 2049634 9728219 SPAP_2207 Streptococcus pneumoniae AP200 L-fucose isomerase-like protein YP_003877740.1 2047868 R 574093 CDS YP_003877741.1 307068775 9728220 complement(2049691..2052807) 1 NC_014494.1 Operon 983 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 2052807 9728220 SPAP_2208 Streptococcus pneumoniae AP200 hypothetical protein YP_003877741.1 2049691 R 574093 CDS YP_003877742.1 307068776 9728221 complement(2052817..2055111) 1 NC_014494.1 Operon 983 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 2055111 9728221 SPAP_2209 Streptococcus pneumoniae AP200 hypothetical protein YP_003877742.1 2052817 R 574093 CDS YP_003877743.1 307068777 9728222 complement(2055170..2055970) 1 NC_014494.1 Operon 984 Gene 1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 2055970 9728222 SPAP_2210 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID YP_003877743.1 2055170 R 574093 CDS YP_003877744.1 307068778 9728223 complement(2055967..2056740) 1 NC_014494.1 Operon 984 Gene 2 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 2056740 9728223 SPAP_2211 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC YP_003877744.1 2055967 R 574093 CDS YP_003877745.1 307068779 9728224 complement(2056765..2057235) 1 NC_014494.1 Operon 984 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 2057235 9728224 SPAP_2212 Streptococcus pneumoniae AP200 PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB YP_003877745.1 2056765 R 574093 CDS YP_003877746.1 307068780 9728225 complement(2057226..2057669) 1 NC_014494.1 Operon 984 Gene 4 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA 2057669 9728225 SPAP_2213 Streptococcus pneumoniae AP200 PTS system mannose/fructose-specific transporter subunit IIA YP_003877746.1 2057226 R 574093 CDS YP_003877747.1 307068781 9728226 complement(2057650..2058090) 1 NC_014494.1 Operon 984 Gene 5 COG4154 Fucose dissimilation pathway protein FucU; fucose dissimilation pathway protein FucU 2058090 9728226 SPAP_2214 Streptococcus pneumoniae AP200 fucose dissimilation pathway protein FucU YP_003877747.1 2057650 R 574093 CDS YP_003877748.1 307068782 9728227 complement(2058102..2058740) 1 NC_014494.1 Operon 984 Gene 6 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; ribulose-5-phosphate 4-epimerase-like epimerase and aldolase 2058740 9728227 SPAP_2215 Streptococcus pneumoniae AP200 ribulose-5-phosphate 4-epimerase-like epimerase and aldolase YP_003877748.1 2058102 R 574093 CDS YP_003877749.1 307068783 9728228 complement(2058855..2060258) 1 NC_014494.1 Operon 985 Gene 1 COG1070 Sugar (pentulose and hexulose) kinases; sugar (pentulose and hexulose) kinase 2060258 9728228 SPAP_2216 Streptococcus pneumoniae AP200 sugar (pentulose and hexulose) kinase YP_003877749.1 2058855 R 574093 CDS YP_003877750.1 307068784 9728229 2060434..2061207 1 NC_014494.1 Operon 986 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 2061207 9728229 SPAP_2217 Streptococcus pneumoniae AP200 sugar metabolism transcriptional regulator YP_003877750.1 2060434 D 574093 CDS YP_003877751.1 307068785 9728230 2062027..2062125 1 NC_014494.1 Operon 987 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2062125 9728230 SPAP_2218 Streptococcus pneumoniae AP200 hypothetical protein YP_003877751.1 2062027 D 574093 CDS YP_003877752.1 307068786 9728231 complement(2062378..2063883) 1 NC_014494.1 Operon 988 Gene 1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin 2063883 9728231 SPAP_2219 Streptococcus pneumoniae AP200 metal ion ABC transporter periplasmic protein/surface adhesin YP_003877752.1 2062378 R 574093 CDS YP_003877753.1 307068787 9728232 complement(2063893..2064699) 1 NC_014494.1 Operon 988 Gene 2 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease 2064699 9728232 SPAP_2220 Streptococcus pneumoniae AP200 Mn2+/Zn2+ ABC transporter permease YP_003877753.1 2063893 R 574093 CDS YP_003877754.1 307068788 9728233 complement(2064692..2065396) 1 NC_014494.1 Operon 988 Gene 3 COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn/Zn ABC transporter ATPase 2065396 9728233 SPAP_2221 Streptococcus pneumoniae AP200 Mn/Zn ABC transporter ATPase YP_003877754.1 2064692 R 574093 CDS YP_003877755.1 307068789 9728234 complement(2065396..2065836) 1 NC_014494.1 Operon 988 Gene 4 COG1846 Transcriptional regulators; transcriptional regulator 2065836 9728234 SPAP_2222 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877755.1 2065396 R 574093 CDS YP_003877756.1 307068790 9728235 complement(2065991..2066497) 1 NC_014494.1 Operon 989 Gene 1 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) 2066497 9728235 SPAP_2223 Streptococcus pneumoniae AP200 protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) YP_003877756.1 2065991 R 574093 CDS YP_003877757.1 307068791 9728236 complement(2066472..2067260) 1 NC_014494.1 Operon 989 Gene 2 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) 2067260 9728236 SPAP_2224 Streptococcus pneumoniae AP200 protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) YP_003877757.1 2066472 R 574093 CDS YP_003877758.1 307068792 9728237 complement(2067253..2067492) 1 NC_014494.1 Operon 989 Gene 3 COG0236 Acyl carrier protein; acyl carrier protein 2067492 9728237 SPAP_2225 Streptococcus pneumoniae AP200 acyl carrier protein YP_003877758.1 2067253 R 574093 CDS YP_003877759.1 307068793 9728238 complement(2067506..2068750) 1 NC_014494.1 Operon 989 Gene 4 COG1696 Predicted membrane protein involved in D-alanine export; hypothetical protein 2068750 9728238 SPAP_2226 Streptococcus pneumoniae AP200 hypothetical protein YP_003877759.1 2067506 R 574093 CDS YP_003877760.1 307068794 9728239 complement(2068747..2070297) 1 NC_014494.1 Operon 989 Gene 5 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase modules-like protein 2070297 9728239 SPAP_2227 Streptococcus pneumoniae AP200 non-ribosomal peptide synthetase modules-like protein YP_003877760.1 2068747 R 574093 CDS YP_003877761.1 307068795 9728240 complement(2070680..2071384) 1 NC_014494.1 Operon 990 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease 2071384 9728240 SPAP_2228 Streptococcus pneumoniae AP200 glycerol uptake facilitator-like permease YP_003877761.1 2070680 R 574093 CDS YP_003877762.1 307068796 9728241 complement(2071454..2073280) 1 NC_014494.1 Operon 990 Gene 2 COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 2073280 9728241 SPAP_2229 Streptococcus pneumoniae AP200 glycerol-3-phosphate dehydrogenase YP_003877762.1 2071454 R 574093 CDS YP_003877763.1 307068797 9728242 complement(2073322..2074830) 1 NC_014494.1 Operon 990 Gene 3 COG0554 Glycerol kinase; glycerol kinase 2074830 9728242 SPAP_2230 Streptococcus pneumoniae AP200 glycerol kinase YP_003877763.1 2073322 R 574093 CDS YP_003877764.1 307068798 9728243 complement(2074989..2076416) 1 NC_014494.1 Operon 991 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2076416 9728243 SPAP_2231 Streptococcus pneumoniae AP200 hypothetical protein YP_003877764.1 2074989 R 574093 CDS YP_003877765.1 307068799 9728244 2076581..2077453 1 NC_014494.1 Operon 992 Gene 1 COG1281 Disulfide bond chaperones of the HSP33 family; HSP33 family disulfide bond chaperone 2077453 9728244 SPAP_2232 Streptococcus pneumoniae AP200 HSP33 family disulfide bond chaperone YP_003877765.1 2076581 D 574093 CDS YP_003877766.1 307068800 9728245 2077440..2078420 1 NC_014494.1 Operon 992 Gene 2 COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase 2078420 9728245 SPAP_2233 Streptococcus pneumoniae AP200 tRNA-dihydrouridine synthase YP_003877766.1 2077440 D 574093 CDS YP_003877767.1 307068801 9728246 complement(2078650..2080857) 1 NC_014494.1 Operon 993 Gene 1 COG5263 FOG: Choline binding protein A; choline binding protein A 2080857 9728246 SPAP_2234 Streptococcus pneumoniae AP200 choline binding protein A YP_003877767.1 2078650 R 574093 CDS YP_003877768.1 307068802 9728247 complement(2080936..2081463) 1 NC_014494.1 Operon 993 Gene 2 COG1755 Uncharacterized protein conserved in bacteria; hypothetical protein 2081463 9728247 SPAP_2235 Streptococcus pneumoniae AP200 hypothetical protein YP_003877768.1 2080936 R 574093 CDS YP_003877769.1 307068803 9728248 complement(2081546..2082886) 1 NC_014494.1 Operon 994 Gene 1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 2082886 9728248 SPAP_2236 Streptococcus pneumoniae AP200 signal transduction histidine kinase YP_003877769.1 2081546 R 574093 CDS YP_003877770.1 307068804 9728249 complement(2082883..2083536) 1 NC_014494.1 Operon 994 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 2083536 9728249 SPAP_2237 Streptococcus pneumoniae AP200 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator YP_003877770.1 2082883 R 574093 CDS YP_003877771.1 307068805 9728250 complement(2083845..2086277) 1 NC_014494.1 Operon 995 Gene 1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATPase 2086277 9728250 SPAP_2238 Streptococcus pneumoniae AP200 ATPase YP_003877771.1 2083845 R 574093 CDS YP_003877772.1 307068806 9728251 complement(2086279..2086737) 1 NC_014494.1 Operon 995 Gene 2 COG4463 Transcriptional repressor of class III stress genes; transcriptional repressor of class III stress genes 2086737 9728251 SPAP_2239 Streptococcus pneumoniae AP200 transcriptional repressor of class III stress genes YP_003877772.1 2086279 R 574093 CDS YP_003877773.1 307068807 9728252 complement(2086856..2087584) 1 NC_014494.1 Operon 996 Gene 1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; nitrate/sulfonate/bicarbonate ABC transporter ATPase 2087584 9728252 SPAP_2240 Streptococcus pneumoniae AP200 nitrate/sulfonate/bicarbonate ABC transporter ATPase YP_003877773.1 2086856 R 574093 CDS YP_003877774.1 307068808 9728253 complement(2087584..2088591) 1 NC_014494.1 Operon 996 Gene 2 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 2088591 9728253 SPAP_2241 Streptococcus pneumoniae AP200 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_003877774.1 2087584 R 574093 CDS YP_003877775.1 307068809 9728254 complement(2088630..2089388) 1 NC_014494.1 Operon 996 Gene 3 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; nitrate/sulfonate/bicarbonate ABC transporter permease 2089388 9728254 SPAP_2242 Streptococcus pneumoniae AP200 nitrate/sulfonate/bicarbonate ABC transporter permease YP_003877775.1 2088630 R 574093 CDS YP_003877776.1 307068810 9728255 complement(2089351..2089641) 1 NC_014494.1 Operon 996 Gene 4 COG0011 Uncharacterized conserved protein; hypothetical protein 2089641 9728255 SPAP_2243 Streptococcus pneumoniae AP200 hypothetical protein YP_003877776.1 2089351 R 574093 CDS YP_003877777.1 307068811 9728256 complement(2089897..2091153) 1 NC_014494.1 Operon 997 Gene 1 COG3942 Choline binding protein D; choline binding protein D 2091153 9728256 SPAP_2244 Streptococcus pneumoniae AP200 choline binding protein D YP_003877777.1 2089897 R 574093 CDS YP_003877778.1 307068812 9728257 complement(2091332..2091598) 1 NC_014494.1 Operon 998 Gene 1 COG4466 Uncharacterized protein conserved in bacteria; hypothetical protein 2091598 9728257 SPAP_2245 Streptococcus pneumoniae AP200 hypothetical protein YP_003877778.1 2091332 R 574093 CDS YP_003877779.1 307068813 9728258 complement(2091600..2092952) 1 NC_014494.1 Operon 998 Gene 2 COG0305 Replicative DNA helicase; Replicative DNA helicase 2092952 9728258 SPAP_2246 Streptococcus pneumoniae AP200 Replicative DNA helicase YP_003877779.1 2091600 R 574093 CDS YP_003877780.1 307068814 9728259 complement(2092996..2093448) 1 NC_014494.1 Operon 998 Gene 3 protein supported gi|15902011|ref|NP_346615.1| 50S ribosomal protein L9; hypothetical protein 2093448 9728259 SPAP_2247 Streptococcus pneumoniae AP200 hypothetical protein YP_003877780.1 2092996 R 574093 CDS YP_003877781.1 307068815 9728260 complement(2093445..2095319) 1 NC_014494.1 Operon 998 Gene 4 COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain; putative signaling protein 2095319 9728260 SPAP_2248 Streptococcus pneumoniae AP200 putative signaling protein YP_003877781.1 2093445 R 574093 CDS YP_003877782.1 307068816 9728261 complement(2095554..2096102) 1 NC_014494.1 Operon 999 Gene 1 protein supported gi|148984509|ref|ZP_01817797.1| ribosomal subunit interface protein; hypothetical protein 2096102 9728261 SPAP_2249 Streptococcus pneumoniae AP200 hypothetical protein YP_003877782.1 2095554 R 574093 CDS YP_003877783.1 307068817 9728262 complement(2096182..2096520) 1 NC_014494.1 Operon 999 Gene 2 COG1040 Predicted amidophosphoribosyltransferases; putative amidophosphoribosyltransferase 2096520 9728262 SPAP_2250 Streptococcus pneumoniae AP200 putative amidophosphoribosyltransferase YP_003877783.1 2096182 R 574093 CDS YP_003877784.1 307068818 9728263 complement(2096841..2098139) 1 NC_014494.1 Operon 1000 Gene 1 COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein); superfamily II DNA/RNA helicase 2098139 9728263 SPAP_2251 Streptococcus pneumoniae AP200 superfamily II DNA/RNA helicase YP_003877784.1 2096841 R 574093 CDS YP_003877785.1 307068819 9728264 2098195..2098830 1 NC_014494.1 Operon 1001 Gene 1 COG1739 Uncharacterized conserved protein; hypothetical protein 2098830 9728264 SPAP_2252 Streptococcus pneumoniae AP200 hypothetical protein YP_003877785.1 2098195 D 574093 CDS YP_003877786.1 307068820 9728265 2099115..2100035 1 NC_014494.1 Operon 1002 Gene 1 protein supported gi|148988856|ref|ZP_01820271.1| 50S ribosomal protein L9; hypothetical protein 2100035 9728265 SPAP_2253 Streptococcus pneumoniae AP200 hypothetical protein YP_003877786.1 2099115 D 574093 CDS YP_003877787.1 307068821 9728266 complement(2100232..2100501) 1 NC_014494.1 Operon 1003 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_6 2100501 9728266 SPAP_2254 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_6 YP_003877787.1 2100232 R 574093 CDS YP_003877788.1 307068822 9728267 2100667..2100933 1 NC_014494.1 Operon 1004 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 2100933 9728267 SPAP_2255 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn2 YP_003877788.1 2100667 D 574093 CDS YP_003877789.1 307068823 9728268 complement(2101124..2101411) 1 NC_014494.1 Operon 1005 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_7 2101411 9728268 SPAP_2256 Streptococcus pneumoniae AP200 transposase-like protein, ISSpn_AP200_7 YP_003877789.1 2101124 R 574093 CDS YP_003877790.1 307068824 9728269 complement(2101657..2102697) 1 NC_014494.1 Operon 1006 Gene 1 COG0264 Translation elongation factor Ts; translation elongation factor Ts 2102697 9728269 SPAP_2257 Streptococcus pneumoniae AP200 translation elongation factor Ts YP_003877790.1 2101657 R 574093 CDS YP_003877791.1 307068825 9728270 complement(2102776..2103636) 1 NC_014494.1 Operon 1006 Gene 2 protein supported gi|242244394|ref|ZP_04798831.1| 30S ribosomal protein S2; 30S ribosomal protein S2 2103636 9728270 SPAP_2258 Streptococcus pneumoniae AP200 30S ribosomal protein S2 YP_003877791.1 2102776 R 574093 CDS YP_003877792.1 307068826 9728271 complement(2103779..2104957) 1 NC_014494.1 Operon 1007 Gene 1 COG3883 Uncharacterized protein conserved in bacteria; hypothetical protein 2104957 9728271 SPAP_2259 Streptococcus pneumoniae AP200 hypothetical protein YP_003877792.1 2103779 R 574093 CDS YP_003877793.1 307068827 9728272 complement(2105050..2105544) 1 NC_014494.1 Operon 1007 Gene 2 COG2891 Cell shape-determining protein; cell shape-determining protein 2105544 9728272 SPAP_2260 Streptococcus pneumoniae AP200 cell shape-determining protein YP_003877793.1 2105050 R 574093 CDS YP_003877794.1 307068828 9728273 complement(2105544..2106362) 1 NC_014494.1 Operon 1007 Gene 3 COG1792 Cell shape-determining protein; cell shape-determining protein 2106362 9728273 SPAP_2261 Streptococcus pneumoniae AP200 cell shape-determining protein YP_003877794.1 2105544 R 574093 CDS YP_003877795.1 307068829 9728274 complement(2106421..2107215) 1 NC_014494.1 Operon 1007 Gene 4 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter 2107215 9728274 SPAP_2262 Streptococcus pneumoniae AP200 cobalt ABC transporter permease CbiQ-like transporter YP_003877795.1 2106421 R 574093 CDS YP_003877796.1 307068830 9728275 complement(2107208..2108047) 1 NC_014494.1 Operon 1007 Gene 5 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 2108047 9728275 SPAP_2263 Streptococcus pneumoniae AP200 cobalt ABC transporter ATPase YP_003877796.1 2107208 R 574093 CDS YP_003877797.1 307068831 9728276 complement(2108032..2108859) 1 NC_014494.1 Operon 1007 Gene 6 protein supported gi|229849245|ref|ZP_04469311.1| LSU ribosomal protein L17P; hypothetical protein 2108859 9728276 SPAP_2264 Streptococcus pneumoniae AP200 hypothetical protein YP_003877797.1 2108032 R 574093 CDS YP_003877798.1 307068832 9728277 complement(2108856..2109401) 1 NC_014494.1 Operon 1007 Gene 7 COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthase 2109401 9728277 SPAP_2265 Streptococcus pneumoniae AP200 phosphatidylglycerophosphate synthase YP_003877798.1 2108856 R 574093 CDS YP_003877799.1 307068833 9728278 complement(2109412..2110233) 1 NC_014494.1 Operon 1007 Gene 8 COG1426 Uncharacterized protein conserved in bacteria; hypothetical protein 2110233 9728278 SPAP_2266 Streptococcus pneumoniae AP200 hypothetical protein YP_003877799.1 2109412 R 574093 CDS YP_003877800.1 307068834 9728279 complement(2110275..2111558) 1 NC_014494.1 Operon 1007 Gene 9 COG0612 Predicted Zn-dependent peptidases; putative Zn-dependent peptidase 2111558 9728279 SPAP_2267 Streptococcus pneumoniae AP200 putative Zn-dependent peptidase YP_003877800.1 2110275 R 574093 CDS YP_003877801.1 307068835 9728280 complement(2111555..2112805) 1 NC_014494.1 Operon 1007 Gene 10 COG0612 Predicted Zn-dependent peptidases; putative Zn-dependent peptidase 2112805 9728280 SPAP_2268 Streptococcus pneumoniae AP200 putative Zn-dependent peptidase YP_003877801.1 2111555 R 574093 CDS YP_003877802.1 307068836 9728281 2112964..2113332 1 NC_014494.1 Operon 1008 Gene 1 protein supported gi|15904072|ref|NP_359622.1| hypothetical protein spr2031; hypothetical protein 2113332 9728281 SPAP_2269 Streptococcus pneumoniae AP200 hypothetical protein YP_003877802.1 2112964 D 574093 CDS YP_003877803.1 307068837 9728282 2113335..2114432 1 NC_014494.1 Operon 1008 Gene 2 COG1195 Recombinational DNA repair ATPase (RecF pathway); recombinational DNA repair ATPase 2114432 9728282 SPAP_2270 Streptococcus pneumoniae AP200 recombinational DNA repair ATPase YP_003877803.1 2113335 D 574093 CDS YP_003877804.1 307068838 9728283 complement(2114483..2115961) 1 NC_014494.1 Operon 1009 Gene 1 COG0516 IMP dehydrogenase/GMP reductase; IMP dehydrogenase/GMP reductase 2115961 9728283 SPAP_2271 Streptococcus pneumoniae AP200 IMP dehydrogenase/GMP reductase YP_003877804.1 2114483 R 574093 CDS YP_003877805.1 307068839 9728284 complement(2116113..2117138) 1 NC_014494.1 Operon 1010 Gene 1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 2117138 9728284 SPAP_2272 Streptococcus pneumoniae AP200 tryptophanyl-tRNA synthetase YP_003877805.1 2116113 R 574093 CDS YP_003877806.1 307068840 9728285 2117344..2118966 1 NC_014494.1 Operon 1011 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 2118966 9728285 SPAP_2273 Streptococcus pneumoniae AP200 ABC transporter ATPase YP_003877806.1 2117344 D 574093 CDS YP_003877807.1 307068841 9728286 2119028..2121580 1 NC_014494.1 Operon 1011 Gene 2 COG4485 Predicted membrane protein; hypothetical protein 2121580 9728286 SPAP_2274 Streptococcus pneumoniae AP200 hypothetical protein YP_003877807.1 2119028 D 574093 CDS YP_003877808.1 307068842 9728287 complement(2121681..2121995) 1 NC_014494.1 Operon 1012 Gene 1 COG1511 Predicted membrane protein; hypothetical protein 2121995 9728287 SPAP_2275 Streptococcus pneumoniae AP200 hypothetical protein YP_003877808.1 2121681 R 574093 CDS YP_003877809.1 307068843 9728288 complement(2122023..2123138) 1 NC_014494.1 Operon 1012 Gene 2 COG1511 Predicted membrane protein; hypothetical protein 2123138 9728288 SPAP_2276 Streptococcus pneumoniae AP200 hypothetical protein YP_003877809.1 2122023 R 574093 CDS YP_003877810.1 307068844 9728289 2123369..2123836 1 NC_014494.1 Operon 1013 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 2123836 9728289 SPAP_2277 Streptococcus pneumoniae AP200 transcriptional regulator YP_003877810.1 2123369 D 574093 CDS YP_003877811.1 307068845 9728292 complement(2124154..2124906) 1 NC_014494.1 Operon 1014 Gene 1 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 2124906 9728292 SPAP_2280 Streptococcus pneumoniae AP200 LytR/AlgR family response regulator YP_003877811.1 2124154 R 574093 CDS YP_003877812.1 307068846 9728293 complement(2124903..2126228) 1 NC_014494.1 Operon 1014 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 2126228 9728293 SPAP_2281 Streptococcus pneumoniae AP200 putative signal transduction protein YP_003877812.1 2124903 R 574093 CDS YP_003877813.1 307068847 9728294 complement(2126413..2126931) 1 NC_014494.1 transposase-like protein, IS1239 2126931 9728294 SPAP_2283 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877813.1 2126413 R 574093 CDS YP_003877814.1 307068848 9728295 complement(2126951..2127253) 1 NC_014494.1 transposase-like protein, IS1239 2127253 9728295 SPAP_2284 Streptococcus pneumoniae AP200 transposase-like protein, IS1239 YP_003877814.1 2126951 R 574093 CDS YP_003877815.1 307068849 9728296 complement(2127476..2127622) 1 NC_014494.1 Operon 1016 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2127622 9728296 SPAP_2285 Streptococcus pneumoniae AP200 hypothetical protein YP_003877815.1 2127476 R 574093 CDS YP_003877816.1 307068850 9728298 complement(2127905..2128384) 1 NC_014494.1 Operon 1016 Gene 2 COG1576 Uncharacterized conserved protein; hypothetical protein 2128384 9728298 SPAP_2287 Streptococcus pneumoniae AP200 hypothetical protein YP_003877816.1 2127905 R 574093 CDS YP_003877817.1 307068851 9728299 2128555..2129748 1 NC_014494.1 Operon 1017 Gene 1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; trypsin-like serine protease 2129748 9728299 SPAP_2288 Streptococcus pneumoniae AP200 trypsin-like serine protease YP_003877817.1 2128555 D 574093 CDS YP_003877818.1 307068852 9728300 2129806..2130564 1 NC_014494.1 Operon 1017 Gene 2 COG1475 Predicted transcriptional regulators; putative transcriptional regulator 2130564 9728300 SPAP_2289 Streptococcus pneumoniae AP200 putative transcriptional regulator YP_003877818.1 2129806 D 574093 CDS