-- dump date 20120504_163123 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_140435.1 55821994 3166013 186..1550 1 NC_006449.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1550 dnaA 3166013 dnaA Streptococcus thermophilus CNRZ1066 chromosome replication initiator DnaA YP_140435.1 186 D 299768 CDS YP_140436.1 55821995 3166960 1705..2841 1 NC_006449.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2841 dnaN 3166960 dnaN Streptococcus thermophilus CNRZ1066 DNA polymerase III subunit beta YP_140436.1 1705 D 299768 CDS YP_140437.1 55821996 3166659 2892..3083 1 NC_006449.1 hypothetical protein 3083 3166659 str0003 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140437.1 2892 D 299768 CDS YP_140438.1 55821997 3166054 3296..4411 1 NC_006449.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4411 3166054 str0004 Streptococcus thermophilus CNRZ1066 GTP-dependent nucleic acid-binding protein EngD YP_140438.1 3296 D 299768 CDS YP_140439.1 55821998 3167020 4484..5053 1 NC_006449.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 5053 pth 3167020 pth Streptococcus thermophilus CNRZ1066 peptidyl-tRNA hydrolase YP_140439.1 4484 D 299768 CDS YP_140440.1 55821999 3166956 5046..8552 1 NC_006449.1 transcription repair coupling factor 8552 trcF 3166956 trcF Streptococcus thermophilus CNRZ1066 transcription repair coupling factor YP_140440.1 5046 D 299768 CDS YP_140441.1 55822000 3166977 8738..9013 1 NC_006449.1 hypothetical protein 9013 3166977 str0007 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140441.1 8738 D 299768 CDS YP_140442.1 55822001 3167055 8997..9368 1 NC_006449.1 MesJ/Ycf62 family cell-cycle protein 9368 divIC 3167055 divIC Streptococcus thermophilus CNRZ1066 MesJ/Ycf62 family cell-cycle protein YP_140442.1 8997 D 299768 CDS YP_140443.1 55822002 3167058 9496..10788 1 NC_006449.1 hypothetical protein 10788 3167058 str0009 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140443.1 9496 D 299768 CDS YP_140444.1 55822003 3167012 10788..12053 1 NC_006449.1 cell-cycle protein MesJ/Ycf62 family 12053 3167012 str0010 Streptococcus thermophilus CNRZ1066 cell-cycle protein MesJ/Ycf62 family YP_140444.1 10788 D 299768 CDS YP_140445.1 55822004 3167061 12135..12677 1 NC_006449.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 12677 hpt 3167061 hpt Streptococcus thermophilus CNRZ1066 hypoxanthine-guanine phosphoribosyltransferase YP_140445.1 12135 D 299768 CDS YP_140446.1 55822005 3167022 12693..14660 1 NC_006449.1 cell division protein 14660 ftsH 3167022 ftsH Streptococcus thermophilus CNRZ1066 cell division protein YP_140446.1 12693 D 299768 CDS YP_140447.1 55822006 3166542 complement(14678..14899) 1 NC_006449.1 truncated; hypothetical protein 14899 3166542 str0013 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140447.1 14678 R 299768 CDS YP_140448.1 55822007 3166316 complement(14978..15703) 1 NC_006449.1 truncated; hypothetical protein 15703 3166316 str0014 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140448.1 14978 R 299768 CDS YP_140449.1 55822008 3166980 complement(15621..15905) 1 NC_006449.1 truncated; hypothetical protein 15905 3166980 str0015 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140449.1 15621 R 299768 CDS YP_140450.1 55822009 3167026 16063..16347 1 NC_006449.1 truncated; hypothetical protein 16347 3167026 str0016 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140450.1 16063 D 299768 CDS YP_140451.1 55822010 3167015 16409..16624 1 NC_006449.1 truncated; hypothetical protein 16624 3167015 str0017 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140451.1 16409 D 299768 CDS YP_140452.1 55822011 3166736 16573..16911 1 NC_006449.1 truncated; hypothetical protein 16911 3166736 str0018 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140452.1 16573 D 299768 CDS YP_140453.1 55822012 3167040 16871..17413 1 NC_006449.1 truncated; hypothetical protein 17413 3167040 str0019 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140453.1 16871 D 299768 CDS YP_140454.1 55822013 3167009 24266..25096 1 NC_006449.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 25096 mreC 3167009 mreC Streptococcus thermophilus CNRZ1066 rod shape-determining protein MreC YP_140454.1 24266 D 299768 CDS YP_140455.1 55822014 3165734 25044..25622 1 NC_006449.1 rod shape-determining protein MreD 25622 mreD 3165734 mreD Streptococcus thermophilus CNRZ1066 rod shape-determining protein MreD YP_140455.1 25044 D 299768 CDS YP_140456.1 55822015 3167014 25707..27164 1 NC_006449.1 glucan binding protein 27164 pcsB 3167014 pcsB Streptococcus thermophilus CNRZ1066 glucan binding protein YP_140456.1 25707 D 299768 CDS YP_140457.1 55822016 3167038 27366..28343 1 NC_006449.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 28343 prsA1 3167038 prsA1 Streptococcus thermophilus CNRZ1066 ribose-phosphate pyrophosphokinase YP_140457.1 27366 D 299768 CDS YP_140458.1 55822017 3167101 complement(28385..28660) 1 NC_006449.1 truncated; truncated IS1193 transposase 28660 3167101 str0024 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_140458.1 28385 R 299768 CDS YP_140459.1 55822018 3167065 29442..30626 1 NC_006449.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 30626 araT 3167065 araT Streptococcus thermophilus CNRZ1066 aromatic amino acid aminotransferase YP_140459.1 29442 D 299768 CDS YP_140460.1 55822019 3166661 30613..31386 1 NC_006449.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 31386 recO 3166661 recO Streptococcus thermophilus CNRZ1066 DNA repair protein RecO YP_140460.1 30613 D 299768 CDS YP_140461.1 55822020 3167008 31602..32606 1 NC_006449.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 32606 plsX 3167008 plsX Streptococcus thermophilus CNRZ1066 glycerol-3-phosphate acyltransferase PlsX YP_140461.1 31602 D 299768 CDS YP_140462.1 55822021 3166788 32633..32851 1 NC_006449.1 acyl carrier protein 32851 acpP1 3166788 acpP1 Streptococcus thermophilus CNRZ1066 acyl carrier protein YP_140462.1 32633 D 299768 CDS YP_140463.1 55822022 3167013 33136..33843 1 NC_006449.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 33843 purC 3167013 purC Streptococcus thermophilus CNRZ1066 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_140463.1 33136 D 299768 CDS YP_140464.1 55822023 3167010 33875..37624 1 NC_006449.1 phosphoribosylformylglycinamidine synthase II 37624 purL 3167010 purL Streptococcus thermophilus CNRZ1066 phosphoribosylformylglycinamidine synthase II YP_140464.1 33875 D 299768 CDS YP_140465.1 55822024 3166939 37793..39232 1 NC_006449.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 39232 purF 3166939 purF Streptococcus thermophilus CNRZ1066 amidophosphoribosyltransferase YP_140465.1 37793 D 299768 CDS YP_140466.1 55822025 3167025 39263..40282 1 NC_006449.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 40282 purM 3167025 purM Streptococcus thermophilus CNRZ1066 phosphoribosylaminoimidazole synthetase YP_140466.1 39263 D 299768 CDS YP_140467.1 55822026 3165661 40282..40836 1 NC_006449.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 40836 purN 3165661 purN Streptococcus thermophilus CNRZ1066 phosphoribosylglycinamide formyltransferase YP_140467.1 40282 D 299768 CDS YP_140468.1 55822027 3166965 40854..42452 1 NC_006449.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 42452 purH 3166965 purH Streptococcus thermophilus CNRZ1066 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_140468.1 40854 D 299768 CDS YP_140469.1 55822028 3167052 42710..43081 1 NC_006449.1 truncated; hypothetical protein 43081 3167052 str0036 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140469.1 42710 D 299768 CDS YP_140470.1 55822029 3167002 43135..43467 1 NC_006449.1 truncated; hypothetical protein 43467 3167002 str0037 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140470.1 43135 D 299768 CDS YP_140471.1 55822030 3166999 43636..43743 1 NC_006449.1 truncated; hypothetical protein 43743 3166999 str0038 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140471.1 43636 D 299768 CDS YP_140472.1 55822031 3167011 complement(43848..44687) 1 NC_006449.1 cell wall protein precursor, choline binding protein 44687 cbpD1 3167011 cbpD1 Streptococcus thermophilus CNRZ1066 cell wall protein precursor, choline binding protein YP_140472.1 43848 R 299768 CDS YP_140473.1 55822032 3167034 44995..46257 1 NC_006449.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 46257 purD 3167034 purD Streptococcus thermophilus CNRZ1066 phosphoribosylamine--glycine ligase YP_140473.1 44995 D 299768 CDS YP_140474.1 55822033 3167037 46591..47091 1 NC_006449.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 47091 purE 3167037 purE Streptococcus thermophilus CNRZ1066 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_140474.1 46591 D 299768 CDS YP_140475.1 55822034 3165630 47078..48169 1 NC_006449.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 48169 purK 3165630 purK Streptococcus thermophilus CNRZ1066 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_140475.1 47078 D 299768 CDS YP_140476.1 55822035 3166990 48362..49117 1 NC_006449.1 hypothetical protein 49117 3166990 str0043 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140476.1 48362 D 299768 CDS YP_140477.1 55822036 3166220 49189..49353 1 NC_006449.1 hypothetical protein 49353 3166220 str0044 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140477.1 49189 D 299768 CDS YP_140478.1 55822037 3167054 49632..50930 1 NC_006449.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 50930 purB1 3167054 purB1 Streptococcus thermophilus CNRZ1066 adenylosuccinate lyase YP_140478.1 49632 D 299768 CDS YP_140479.1 55822038 3166944 complement(51794..53485) 1 NC_006449.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 53485 argS 3166944 argS Streptococcus thermophilus CNRZ1066 arginyl-tRNA synthetase YP_140479.1 51794 R 299768 CDS YP_140480.1 55822039 3166485 53610..54068 1 NC_006449.1 arginine repressor ArgR 54068 argR 3166485 argR Streptococcus thermophilus CNRZ1066 arginine repressor ArgR YP_140480.1 53610 D 299768 CDS YP_140481.1 55822040 3167021 54068..54427 1 NC_006449.1 hypothetical protein 54427 3167021 str0049 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140481.1 54068 D 299768 CDS YP_140482.1 55822041 3167043 54420..56978 1 NC_006449.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 56978 mutS1 3167043 mutS1 Streptococcus thermophilus CNRZ1066 DNA mismatch repair protein MutS YP_140482.1 54420 D 299768 CDS YP_140483.1 55822042 3167491 complement(57225..57467) 1 NC_006449.1 hypothetical protein 57467 3167491 str0051 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140483.1 57225 R 299768 CDS YP_140484.1 55822043 3167053 complement(57481..57855) 1 NC_006449.1 hypothetical protein 57855 3167053 str0052 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140484.1 57481 R 299768 CDS YP_140485.1 55822044 3166353 58079..58384 1 NC_006449.1 hypothetical protein 58384 3166353 str0053 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140485.1 58079 D 299768 CDS YP_140486.1 55822045 3167000 58436..60379 1 NC_006449.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 60379 mutL 3167000 mutL Streptococcus thermophilus CNRZ1066 DNA mismatch repair protein YP_140486.1 58436 D 299768 CDS YP_140487.1 55822046 3167003 60506..60730 1 NC_006449.1 hypothetical protein 60730 3167003 str0055 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140487.1 60506 D 299768 CDS YP_140488.1 55822047 3167047 60882..61472 1 NC_006449.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 61472 ruvA 3167047 ruvA Streptococcus thermophilus CNRZ1066 Holliday junction DNA helicase RuvA YP_140488.1 60882 D 299768 CDS YP_140489.1 55822048 3166996 61479..61655 1 NC_006449.1 truncated; 3-methyl-adenine DNA glycosylase I 61655 3166996 str0057 Streptococcus thermophilus CNRZ1066 3-methyl-adenine DNA glycosylase I YP_140489.1 61479 D 299768 CDS YP_140490.1 55822049 3166341 61789..62034 1 NC_006449.1 truncated; 3-methyl-adenine DNA glycosylase I 62034 3166341 str0058 Streptococcus thermophilus CNRZ1066 3-methyl-adenine DNA glycosylase I YP_140490.1 61789 D 299768 CDS YP_140491.1 55822050 3166998 62130..63401 1 NC_006449.1 competence damage-inducible protein A 63401 cinA 3166998 cinA Streptococcus thermophilus CNRZ1066 competence damage-inducible protein A YP_140491.1 62130 D 299768 CDS YP_140492.1 55822051 3166817 63437..64591 1 NC_006449.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 64591 recA 3166817 recA Streptococcus thermophilus CNRZ1066 recombinase A YP_140492.1 63437 D 299768 CDS YP_140493.1 55822052 3165856 64768..65166 1 NC_006449.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 65166 spxA 3165856 spxA Streptococcus thermophilus CNRZ1066 transcriptional regulator Spx YP_140493.1 64768 D 299768 CDS YP_140494.1 55822053 3166966 71574..75968 1 NC_006449.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 75968 polC 3166966 polC Streptococcus thermophilus CNRZ1066 DNA polymerase III PolC YP_140494.1 71574 D 299768 CDS YP_140495.1 55822054 3166487 76132..77373 1 NC_006449.1 aminopeptidase 77373 pepS 3166487 pepS Streptococcus thermophilus CNRZ1066 aminopeptidase YP_140495.1 76132 D 299768 CDS YP_140496.1 55822055 3165702 77393..77623 1 NC_006449.1 hypothetical protein 77623 3165702 str0064 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140496.1 77393 D 299768 CDS YP_140497.1 55822056 3167006 77826..78155 1 NC_006449.1 truncated; MarR family transcriptional regulator 78155 3167006 str0065 Streptococcus thermophilus CNRZ1066 MarR family transcriptional regulator YP_140497.1 77826 D 299768 CDS YP_140498.1 55822057 3166970 78273..78824 1 NC_006449.1 hypothetical protein 78824 3166970 str0066 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140498.1 78273 D 299768 CDS YP_140499.1 55822058 3167051 complement(78874..79416) 1 NC_006449.1 truncated; hypothetical protein 79416 3167051 str0067 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140499.1 78874 R 299768 CDS YP_140500.1 55822059 3166543 complement(79376..79639) 1 NC_006449.1 truncated; hypothetical protein 79639 3166543 str0069 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140500.1 79376 R 299768 CDS YP_140501.1 55822060 3166196 complement(79766..80038) 1 NC_006449.1 hypothetical protein 80038 3166196 str0070 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140501.1 79766 R 299768 CDS YP_140502.1 55822061 3166687 complement(80256..80693) 1 NC_006449.1 truncated; bacteriocin self-immunity protein , truncated 80693 3166687 str0071 Streptococcus thermophilus CNRZ1066 bacteriocin self-immunity protein , truncated YP_140502.1 80256 R 299768 CDS YP_140503.1 55822062 3166997 complement(80690..81208) 1 NC_006449.1 truncated; bacteriocin self-immunity protein , truncated 81208 3166997 str0072 Streptococcus thermophilus CNRZ1066 bacteriocin self-immunity protein , truncated YP_140503.1 80690 R 299768 CDS YP_140504.1 55822063 3166967 81731..82498 1 NC_006449.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 82498 rpsB 3166967 rpsB Streptococcus thermophilus CNRZ1066 30S ribosomal protein S2 YP_140504.1 81731 D 299768 CDS YP_140505.2 161936385 3166937 82609..83649 1 NC_006449.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 83649 tsf 3166937 tsf Streptococcus thermophilus CNRZ1066 elongation factor Ts YP_140505.2 82609 D 299768 CDS YP_140506.1 55822065 3167036 complement(83760..84230) 1 NC_006449.1 small multidrug export related protein 84230 qacE 3167036 qacE Streptococcus thermophilus CNRZ1066 small multidrug export related protein YP_140506.1 83760 R 299768 CDS YP_140507.1 55822066 3167005 84474..84929 1 NC_006449.1 class III stress genes transcriptional regulator 84929 ctsR 3167005 ctsR Streptococcus thermophilus CNRZ1066 class III stress genes transcriptional regulator YP_140507.1 84474 D 299768 CDS YP_140508.1 55822067 3167016 84930..87380 1 NC_006449.1 ATP-dependent Clp protease, ATP-binding subunit 87380 clpC 3167016 clpC Streptococcus thermophilus CNRZ1066 ATP-dependent Clp protease, ATP-binding subunit YP_140508.1 84930 D 299768 CDS YP_140509.1 55822068 3166993 complement(87508..88077) 1 NC_006449.1 truncated; D-alanyl-D-alanine carboxypeptidase, truncated 88077 3166993 str0078 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine carboxypeptidase, truncated YP_140509.1 87508 R 299768 CDS YP_140510.1 55822069 3166521 complement(88345..88740) 1 NC_006449.1 truncated; D-alanyl-D-alanine carboxypeptidase, truncated 88740 3166521 str0079 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine carboxypeptidase, truncated YP_140510.1 88345 R 299768 CDS YP_140511.1 55822070 3167018 complement(88910..90178) 1 NC_006449.1 D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 90178 dacA1 3167018 dacA1 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein YP_140511.1 88910 R 299768 CDS YP_140512.1 55822071 3167004 90366..92591 1 NC_006449.1 polynucleotide phosphorylase 92591 pnpA 3167004 pnpA Streptococcus thermophilus CNRZ1066 polynucleotide phosphorylase YP_140512.1 90366 D 299768 CDS YP_140513.1 55822072 3167017 92600..93370 1 NC_006449.1 hypothetical protein 93370 3167017 str0082 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140513.1 92600 D 299768 CDS YP_140514.1 55822073 3166992 93434..94063 1 NC_006449.1 serine acetyltransferase 94063 cysE1 3166992 cysE1 Streptococcus thermophilus CNRZ1066 serine acetyltransferase YP_140514.1 93434 D 299768 CDS YP_140515.1 55822074 3166134 94445..95788 1 NC_006449.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 95788 cysS 3166134 cysS Streptococcus thermophilus CNRZ1066 cysteinyl-tRNA synthetase YP_140515.1 94445 D 299768 CDS YP_140516.1 55822075 3167007 95781..96182 1 NC_006449.1 hypothetical protein 96182 3167007 str0085 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140516.1 95781 D 299768 CDS YP_140517.1 55822076 3166989 96465..96620 1 NC_006449.1 hypothetical protein 96620 3166989 str0086 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140517.1 96465 D 299768 CDS YP_140518.1 55822077 3167045 96696..96884 1 NC_006449.1 hypothetical protein 96884 3167045 str0087 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140518.1 96696 D 299768 CDS YP_140519.1 55822078 3165960 97246..97989 1 NC_006449.1 tRNA/rRNA methyltransferase 97989 trmH 3165960 trmH Streptococcus thermophilus CNRZ1066 tRNA/rRNA methyltransferase YP_140519.1 97246 D 299768 CDS YP_140520.1 55822079 3166094 97992..98507 1 NC_006449.1 hypothetical protein 98507 3166094 str0089 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140520.1 97992 D 299768 CDS YP_140521.1 55822080 3166954 98516..99376 1 NC_006449.1 hypothetical protein 99376 3166954 str0090 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140521.1 98516 D 299768 CDS YP_140522.1 55822081 3167029 99785..100177 1 NC_006449.1 hypothetical protein 100177 3167029 str0091 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140522.1 99785 D 299768 CDS YP_140523.1 55822082 3166987 100325..101281 1 NC_006449.1 2-dehydropantoate 2-reductase 101281 panE 3166987 panE Streptococcus thermophilus CNRZ1066 2-dehydropantoate 2-reductase YP_140523.1 100325 D 299768 CDS YP_140524.1 55822083 3166959 101490..101936 1 NC_006449.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 101936 rplM 3166959 rplM Streptococcus thermophilus CNRZ1066 50S ribosomal protein L13 YP_140524.1 101490 D 299768 CDS YP_140525.1 55822084 3167032 101964..102356 1 NC_006449.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 102356 rpsI 3167032 rpsI Streptococcus thermophilus CNRZ1066 30S ribosomal protein S9 YP_140525.1 101964 D 299768 CDS YP_140526.1 55822085 3167062 complement(102513..102755) 1 NC_006449.1 truncated; integrase/recombinase , truncated 102755 3167062 str0095 Streptococcus thermophilus CNRZ1066 integrase/recombinase , truncated YP_140526.1 102513 R 299768 CDS YP_140527.1 55822086 3166893 102830..103108 1 NC_006449.1 truncated; transcriptional regulator , truncated 103108 3166893 str0096 Streptococcus thermophilus CNRZ1066 transcriptional regulator , truncated YP_140527.1 102830 D 299768 CDS YP_140528.1 55822087 3167059 103358..103462 1 NC_006449.1 hypothetical protein 103462 3167059 str0097 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140528.1 103358 D 299768 CDS YP_140529.1 55822088 3166936 104313..106439 1 NC_006449.1 truncated; lantibiotic biosynthesis protein, truncated 106439 3166936 str0098 Streptococcus thermophilus CNRZ1066 lantibiotic biosynthesis protein, truncated YP_140529.1 104313 D 299768 CDS YP_140530.1 55822089 3167019 106477..107700 1 NC_006449.1 lantibiotic biosynthesis protein 107700 labC 3167019 labC Streptococcus thermophilus CNRZ1066 lantibiotic biosynthesis protein YP_140530.1 106477 D 299768 CDS YP_140531.1 55822090 3165959 107724..108989 1 NC_006449.1 lantibiotic efflux protein 108989 labT 3165959 labT Streptococcus thermophilus CNRZ1066 lantibiotic efflux protein YP_140531.1 107724 D 299768 CDS YP_140532.1 55822091 3166979 109218..109730 1 NC_006449.1 hypothetical protein 109730 3166979 str0101 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140532.1 109218 D 299768 CDS YP_140533.1 55822092 3167031 complement(111053..111295) 1 NC_006449.1 truncated; hypothetical protein 111295 3167031 str0102 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140533.1 111053 R 299768 CDS YP_140534.1 55822093 3167064 complement(111777..112556) 1 NC_006449.1 hypothetical protein 112556 3167064 str0103 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140534.1 111777 R 299768 CDS YP_140535.1 55822094 3167098 complement(112553..112831) 1 NC_006449.1 hypothetical protein 112831 3167098 str0104 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140535.1 112553 R 299768 CDS YP_140536.1 55822095 3165961 113202..114200 1 NC_006449.1 IS1239 transposase 114200 tnp1239 3165961 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_140536.1 113202 D 299768 CDS YP_140537.1 55822096 3166972 complement(114322..114816) 1 NC_006449.1 truncated; hypothetical protein 114816 3166972 str0106 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140537.1 114322 R 299768 CDS YP_140538.1 55822097 3166307 complement(115087..115275) 1 NC_006449.1 truncated; truncated IS1216 transposase 115275 3166307 str0107 Streptococcus thermophilus CNRZ1066 truncated IS1216 transposase YP_140538.1 115087 R 299768 CDS YP_140539.1 55822098 3167122 complement(115281..115775) 1 NC_006449.1 truncated; truncated IS1216 transposase 115775 3167122 str0108 Streptococcus thermophilus CNRZ1066 truncated IS1216 transposase YP_140539.1 115281 R 299768 CDS YP_140540.1 55822099 3165828 115922..116197 1 NC_006449.1 truncated; hypothetical protein 116197 3165828 str0109 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140540.1 115922 D 299768 CDS YP_140541.1 55822100 3167060 116191..116787 1 NC_006449.1 truncated; hypothetical protein 116787 3167060 str0110 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140541.1 116191 D 299768 CDS YP_140542.1 55822101 3166958 116806..117141 1 NC_006449.1 truncated; hypothetical protein 117141 3166958 str0111 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140542.1 116806 D 299768 CDS YP_140543.1 55822102 3167095 117462..117728 1 NC_006449.1 ACT domain-containing protein; hypothetical protein 117728 3167095 str0112 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140543.1 117462 D 299768 CDS YP_140544.1 55822103 3167104 117740..119083 1 NC_006449.1 hypothetical protein 119083 3167104 str0113 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140544.1 117740 D 299768 CDS YP_140545.1 55822104 3167068 119200..119904 1 NC_006449.1 phosphoglycerate mutase 119904 gpmB 3167068 gpmB Streptococcus thermophilus CNRZ1066 phosphoglycerate mutase YP_140545.1 119200 D 299768 CDS YP_140546.1 55822105 3166102 119891..120688 1 NC_006449.1 D-alanyl-D-alanine-carboxypeptidase 120688 dacB 3166102 dacB Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine-carboxypeptidase YP_140546.1 119891 D 299768 CDS YP_140547.1 55822106 3166942 120685..121269 1 NC_006449.1 peptidoglycan hydrolase 121269 mur3 3166942 mur3 Streptococcus thermophilus CNRZ1066 peptidoglycan hydrolase YP_140547.1 120685 D 299768 CDS YP_140548.1 55822107 3167121 121462..122544 1 NC_006449.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 122544 hrcA 3167121 hrcA Streptococcus thermophilus CNRZ1066 heat-inducible transcription repressor YP_140548.1 121462 D 299768 CDS YP_140549.1 55822108 3167127 122528..123109 1 NC_006449.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 123109 grpE 3167127 grpE Streptococcus thermophilus CNRZ1066 heat shock protein GrpE YP_140549.1 122528 D 299768 CDS YP_140550.1 55822109 3167030 123238..125061 1 NC_006449.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 125061 dnaK 3167030 dnaK Streptococcus thermophilus CNRZ1066 molecular chaperone DnaK YP_140550.1 123238 D 299768 CDS YP_140551.1 55822110 3166089 125488..126621 1 NC_006449.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 126621 dnaJ 3166089 dnaJ Streptococcus thermophilus CNRZ1066 molecular chaperone DnaJ YP_140551.1 125488 D 299768 CDS YP_140552.1 55822111 3165781 126727..127473 1 NC_006449.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 127473 truA 3165781 truA Streptococcus thermophilus CNRZ1066 tRNA pseudouridine synthase A YP_140552.1 126727 D 299768 CDS YP_140553.1 55822112 3165964 127466..128227 1 NC_006449.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 128227 thiD 3165964 thiD Streptococcus thermophilus CNRZ1066 phosphomethylpyrimidine kinase YP_140553.1 127466 D 299768 CDS YP_140554.1 55822113 3167134 128318..128686 1 NC_006449.1 hypothetical protein 128686 3167134 str0124 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140554.1 128318 D 299768 CDS YP_140555.1 55822114 3167077 140630..142597 1 NC_006449.1 oligopeptide ABC transporter substrate-binding protein 142597 amiA2 3167077 amiA2 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein YP_140555.1 140630 D 299768 CDS YP_140556.1 55822115 3166963 complement(142635..143546) 1 NC_006449.1 truncated; truncated IS1193 transposase 143546 3166963 str0126 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_140556.1 142635 R 299768 CDS YP_140557.1 55822116 3165967 144465..144893 1 NC_006449.1 truncated; aminoacylase/N-acyl-L-amino acid amidohydrolase, truncated 144893 3165967 str0127 Streptococcus thermophilus CNRZ1066 aminoacylase/N-acyl-L-amino acid amidohydrolase, truncated YP_140557.1 144465 D 299768 CDS YP_140558.1 55822117 3165968 144966..146165 1 NC_006449.1 cyclopropane-fatty-acyl-phospholipid synthase 146165 cfa 3165968 cfa Streptococcus thermophilus CNRZ1066 cyclopropane-fatty-acyl-phospholipid synthase YP_140558.1 144966 D 299768 CDS YP_140559.1 55822118 3166776 complement(146395..146889) 1 NC_006449.1 truncated; truncated IS1193 transposase 146889 3166776 str0129 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_140559.1 146395 R 299768 CDS YP_140560.1 55822119 3166950 147643..148140 1 NC_006449.1 transcriptional regulator 148140 comX 3166950 comX Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140560.1 147643 D 299768 CDS YP_140561.1 55822120 3165712 complement(148240..149082) 1 NC_006449.1 mechanosensitive ion channel MscS 149082 3165712 str0131 Streptococcus thermophilus CNRZ1066 mechanosensitive ion channel MscS YP_140561.1 148240 R 299768 CDS YP_140562.1 55822121 3167048 149223..150506 1 NC_006449.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 150506 tig 3167048 tig Streptococcus thermophilus CNRZ1066 trigger factor YP_140562.1 149223 D 299768 CDS YP_140563.1 55822122 3165965 150664..151245 1 NC_006449.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 151245 rpoE 3165965 rpoE Streptococcus thermophilus CNRZ1066 DNA-directed RNA polymerase subunit delta YP_140563.1 150664 D 299768 CDS YP_140564.1 55822123 3166962 151496..153100 1 NC_006449.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 153100 pyrG 3166962 pyrG Streptococcus thermophilus CNRZ1066 CTP synthetase YP_140564.1 151496 D 299768 CDS YP_140565.1 55822124 3165969 153195..153665 1 NC_006449.1 hypothetical protein 153665 3165969 str0135 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140565.1 153195 D 299768 CDS YP_140566.1 55822125 3165963 153799..154128 1 NC_006449.1 truncated; MutT/nudix family protein, truncated 154128 3165963 str0136 Streptococcus thermophilus CNRZ1066 MutT/nudix family protein, truncated YP_140566.1 153799 D 299768 CDS YP_140567.1 55822126 3167073 154128..155081 1 NC_006449.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 155081 prmA 3167073 prmA Streptococcus thermophilus CNRZ1066 ribosomal protein L11 methyltransferase YP_140567.1 154128 D 299768 CDS YP_140568.1 55822127 3166982 155082..155825 1 NC_006449.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 155825 3166982 str0138 Streptococcus thermophilus CNRZ1066 16S ribosomal RNA methyltransferase RsmE YP_140568.1 155082 D 299768 CDS YP_140569.1 55822128 3167078 156325..156504 1 NC_006449.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 156504 3167078 str0139 Streptococcus thermophilus CNRZ1066 cyclo-nucleotide phosphodiesterase, truncated YP_140569.1 156325 D 299768 CDS YP_140570.1 55822129 3165971 156461..156709 1 NC_006449.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 156709 3165971 str0140 Streptococcus thermophilus CNRZ1066 cyclo-nucleotide phosphodiesterase, truncated YP_140570.1 156461 D 299768 CDS YP_140571.1 55822130 3165972 156657..157454 1 NC_006449.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 157454 3165972 str0141 Streptococcus thermophilus CNRZ1066 cyclo-nucleotide phosphodiesterase, truncated YP_140571.1 156657 D 299768 CDS YP_140572.1 55822131 3165973 157466..158593 1 NC_006449.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 158593 3165973 str0142 Streptococcus thermophilus CNRZ1066 cyclo-nucleotide phosphodiesterase, truncated YP_140572.1 157466 D 299768 CDS YP_140573.1 55822132 3165974 complement(158580..159107) 1 NC_006449.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 159107 nrdI 3165974 nrdI Streptococcus thermophilus CNRZ1066 flavoprotein NrdI YP_140573.1 158580 R 299768 CDS YP_140574.1 55822133 3165966 159207..161426 1 NC_006449.1 (p)ppGpp synthetase 161426 relA 3165966 relA Streptococcus thermophilus CNRZ1066 (p)ppGpp synthetase YP_140574.1 159207 D 299768 CDS YP_140575.1 55822134 3166792 161439..161882 1 NC_006449.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 161882 dtd 3166792 dtd Streptococcus thermophilus CNRZ1066 D-tyrosyl-tRNA(Tyr) deacylase YP_140575.1 161439 D 299768 CDS YP_140576.1 55822135 3167093 162323..162607 1 NC_006449.1 truncated; 1,6-alpha-glucanhydrolase, truncated 162607 3167093 str0147 Streptococcus thermophilus CNRZ1066 1,6-alpha-glucanhydrolase, truncated YP_140576.1 162323 D 299768 CDS YP_140577.1 55822136 3165970 162555..163052 1 NC_006449.1 truncated; 1,6-alpha-glucanhydrolase, truncated 163052 3165970 str0148 Streptococcus thermophilus CNRZ1066 1,6-alpha-glucanhydrolase, truncated YP_140577.1 162555 D 299768 CDS YP_140578.1 55822137 3165957 163088..163858 1 NC_006449.1 truncated; 1,6-alpha-glucanhydrolase, truncated 163858 3165957 str0149 Streptococcus thermophilus CNRZ1066 1,6-alpha-glucanhydrolase, truncated YP_140578.1 163088 D 299768 CDS YP_140579.1 55822138 3167084 164159..165409 1 NC_006449.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 165409 ilvA 3167084 ilvA Streptococcus thermophilus CNRZ1066 threonine dehydratase YP_140579.1 164159 D 299768 CDS YP_140580.1 55822139 3166804 complement(165570..166184) 1 NC_006449.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 166184 def 3166804 def Streptococcus thermophilus CNRZ1066 peptide deformylase YP_140580.1 165570 R 299768 CDS YP_140581.1 55822140 3166791 complement(166286..166924) 1 NC_006449.1 transcriptional regulator 166924 3166791 str0152 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140581.1 166286 R 299768 CDS YP_140582.1 55822141 3165976 167031..168194 1 NC_006449.1 major facilitator transporter 168194 msf 3165976 msf Streptococcus thermophilus CNRZ1066 major facilitator transporter YP_140582.1 167031 D 299768 CDS YP_140583.1 55822142 3165988 168343..168612 1 NC_006449.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 168612 rpsO 3165988 rpsO Streptococcus thermophilus CNRZ1066 30S ribosomal protein S15 YP_140583.1 168343 D 299768 CDS YP_140584.1 55822143 3166983 complement(168842..169423) 1 NC_006449.1 hypothetical protein 169423 3166983 str0155 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140584.1 168842 R 299768 CDS YP_140585.1 55822144 3167046 169991..170161 1 NC_006449.1 hypothetical protein 170161 3167046 str0156 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140585.1 169991 D 299768 CDS YP_140586.1 55822145 3165962 170248..170355 1 NC_006449.1 hypothetical protein 170355 3165962 str0157 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140586.1 170248 D 299768 CDS YP_140587.1 55822146 3166389 complement(170442..171182) 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 171182 3166389 str0158 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_140587.1 170442 R 299768 CDS YP_140588.1 55822147 3166957 complement(171182..172732) 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 172732 3166957 str0159 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_140588.1 171182 R 299768 CDS YP_140589.1 55822148 3165977 172923..173789 1 NC_006449.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 173789 uppP 3165977 uppP Streptococcus thermophilus CNRZ1066 undecaprenyl pyrophosphate phosphatase YP_140589.1 172923 D 299768 CDS YP_140590.1 55822149 3165975 complement(173935..174150) 1 NC_006449.1 hypothetical protein 174150 3165975 str0161 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140590.1 173935 R 299768 CDS YP_140591.1 55822150 3165794 174416..175165 1 NC_006449.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 175165 mecA 3165794 mecA Streptococcus thermophilus CNRZ1066 adaptor protein YP_140591.1 174416 D 299768 CDS YP_140592.1 55822151 3166974 175169..176326 1 NC_006449.1 polysaccharide biosynthesis protein 176326 rgpG 3166974 rgpG Streptococcus thermophilus CNRZ1066 polysaccharide biosynthesis protein YP_140592.1 175169 D 299768 CDS YP_140593.1 55822152 3165979 176454..177257 1 NC_006449.1 ABC transporter ATP binding protein 177257 3165979 str0164 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140593.1 176454 D 299768 CDS YP_140594.1 55822153 3167099 177294..178556 1 NC_006449.1 hypothetical protein 178556 3167099 str0165 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140594.1 177294 D 299768 CDS YP_140595.1 55822154 3166994 178610..179842 1 NC_006449.1 class V aminotransferase 179842 nifS1 3166994 nifS1 Streptococcus thermophilus CNRZ1066 class V aminotransferase YP_140595.1 178610 D 299768 CDS YP_140596.1 55822155 3165981 179808..180263 1 NC_006449.1 NifU family protein 180263 nifU 3165981 nifU Streptococcus thermophilus CNRZ1066 NifU family protein YP_140596.1 179808 D 299768 CDS YP_140597.1 55822156 3166075 180343..181761 1 NC_006449.1 hypothetical protein 181761 3166075 str0168 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140597.1 180343 D 299768 CDS YP_140598.1 55822157 3165982 182045..182251 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter substrate binding protein, truncated 182251 3165982 str0169 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter substrate binding protein, truncated YP_140598.1 182045 D 299768 CDS YP_140599.1 55822158 3165983 182309..183079 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter substrate binding protein, truncated 183079 3165983 str0170 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter substrate binding protein, truncated YP_140599.1 182309 D 299768 CDS YP_140600.1 55822159 3167027 183003..183278 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter permease, truncated 183278 3167027 str0171 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter permease, truncated YP_140600.1 183003 D 299768 CDS YP_140601.1 55822160 3165991 183384..183857 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter permease, truncated 183857 3165991 str0172 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter permease, truncated YP_140601.1 183384 D 299768 CDS YP_140602.1 55822161 3166292 183885..184322 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter permease, truncated 184322 3166292 str0173 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter permease, truncated YP_140602.1 183885 D 299768 CDS YP_140603.1 55822162 3167105 184294..184536 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter ATP binding protein, truncated 184536 3167105 str0174 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter ATP binding protein, truncated YP_140603.1 184294 D 299768 CDS YP_140604.1 55822163 3165984 184566..184769 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter ATP binding protein, truncated 184769 3165984 str0175 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter ATP binding protein, truncated YP_140604.1 184566 D 299768 CDS YP_140605.1 55822164 3166945 184732..185145 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter ATP binding protein, truncated 185145 3166945 str0176 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter ATP binding protein, truncated YP_140605.1 184732 D 299768 CDS YP_140606.1 55822165 3165978 185040..185378 1 NC_006449.1 truncated; dipeptide/oligopeptide ABC transporter ATP binding protein, truncated 185378 3165978 str0177 Streptococcus thermophilus CNRZ1066 dipeptide/oligopeptide ABC transporter ATP binding protein, truncated YP_140606.1 185040 D 299768 CDS YP_140607.1 55822166 3165987 185380..186318 1 NC_006449.1 oligopeptidepermease 186318 optF 3165987 optF Streptococcus thermophilus CNRZ1066 oligopeptidepermease YP_140607.1 185380 D 299768 CDS YP_140608.1 55822167 3165986 186542..186796 1 NC_006449.1 hypothetical protein 186796 3165986 str0179 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140608.1 186542 D 299768 CDS YP_140609.1 55822168 3167126 186856..187743 1 NC_006449.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 187743 hslO 3167126 hslO Streptococcus thermophilus CNRZ1066 heat shock protein 33 YP_140609.1 186856 D 299768 CDS YP_140610.1 55822169 3167107 187661..188713 1 NC_006449.1 transcriptional regulator 188713 nifR 3167107 nifR Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140610.1 187661 D 299768 CDS YP_140611.1 55822170 3166969 188916..189779 1 NC_006449.1 MutR family transcriptional regulator 189779 3166969 str0182 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_140611.1 188916 D 299768 CDS YP_140612.1 55822171 3167071 190049..192388 1 NC_006449.1 protein kinase 192388 3167071 str0183 Streptococcus thermophilus CNRZ1066 protein kinase YP_140612.1 190049 D 299768 CDS YP_140613.1 55822172 3167115 192389..193657 1 NC_006449.1 peptide-efflux protein 193657 3167115 str0184 Streptococcus thermophilus CNRZ1066 peptide-efflux protein YP_140613.1 192389 D 299768 CDS YP_140614.1 55822173 3167123 193751..194206 1 NC_006449.1 zinc transport transcriptional repressor 194206 adcR 3167123 adcR Streptococcus thermophilus CNRZ1066 zinc transport transcriptional repressor YP_140614.1 193751 D 299768 CDS YP_140615.1 55822174 3167001 194208..194915 1 NC_006449.1 zinc ABC transporter ATP-binding protein 194915 adcC 3167001 adcC Streptococcus thermophilus CNRZ1066 zinc ABC transporter ATP-binding protein YP_140615.1 194208 D 299768 CDS YP_140616.1 55822175 3166953 194881..195720 1 NC_006449.1 zinc ABC transporter permease 195720 adcB 3166953 adcB Streptococcus thermophilus CNRZ1066 zinc ABC transporter permease YP_140616.1 194881 D 299768 CDS YP_140617.1 55822176 3165989 195882..196820 1 NC_006449.1 malate ABC transporter permease 196820 3165989 str0188 Streptococcus thermophilus CNRZ1066 malate ABC transporter permease YP_140617.1 195882 D 299768 CDS YP_140618.1 55822177 3167063 196956..197366 1 NC_006449.1 truncated; PTS system glucose-specific transporter subunit IIABC, truncated 197366 3167063 str0189 Streptococcus thermophilus CNRZ1066 PTS system glucose-specific transporter subunit IIABC, truncated YP_140618.1 196956 D 299768 CDS YP_140619.1 55822178 3165990 197378..197596 1 NC_006449.1 truncated; PTS system glucose-specific transporter subunit IIABC, truncated 197596 3165990 str0190 Streptococcus thermophilus CNRZ1066 PTS system glucose-specific transporter subunit IIABC, truncated YP_140619.1 197378 D 299768 CDS YP_140620.1 55822179 3165985 197612..198538 1 NC_006449.1 truncated; PTS system glucose-specific transporter subunit IIABC, truncated 198538 3165985 str0191 Streptococcus thermophilus CNRZ1066 PTS system glucose-specific transporter subunit IIABC, truncated YP_140620.1 197612 D 299768 CDS YP_140621.1 55822180 3167023 198489..199157 1 NC_006449.1 truncated; PTS system glucose-specific transporter subunit IIABC, truncated 199157 3167023 str0192 Streptococcus thermophilus CNRZ1066 PTS system glucose-specific transporter subunit IIABC, truncated YP_140621.1 198489 D 299768 CDS YP_140622.1 55822181 3167072 199198..200070 1 NC_006449.1 hypothetical protein 200070 3167072 str0193 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140622.1 199198 D 299768 CDS YP_140623.1 55822182 3167056 200155..201528 1 NC_006449.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 201528 pgi 3167056 pgi Streptococcus thermophilus CNRZ1066 glucose-6-phosphate isomerase YP_140623.1 200155 D 299768 CDS YP_140624.2 161936384 3167079 201717..202433 1 NC_006449.1 hypothetical protein 202433 3167079 str0195 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140624.2 201717 D 299768 CDS YP_140625.1 55822184 3166971 202560..202898 1 NC_006449.1 preprotein translocase subunit YajC 202898 yajC 3166971 yajC Streptococcus thermophilus CNRZ1066 preprotein translocase subunit YajC YP_140625.1 202560 D 299768 CDS YP_140626.1 55822185 3166975 203027..203776 1 NC_006449.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 203776 uppS 3166975 uppS Streptococcus thermophilus CNRZ1066 undecaprenyl pyrophosphate synthase YP_140626.1 203027 D 299768 CDS YP_140627.1 55822186 3166981 203789..204583 1 NC_006449.1 phosphatidate cytidylyltransferase 204583 cdsA 3166981 cdsA Streptococcus thermophilus CNRZ1066 phosphatidate cytidylyltransferase YP_140627.1 203789 D 299768 CDS YP_140628.1 55822187 3165992 204600..205862 1 NC_006449.1 processing of a peptide sex pheromone 205862 eep 3165992 eep Streptococcus thermophilus CNRZ1066 processing of a peptide sex pheromone YP_140628.1 204600 D 299768 CDS YP_140629.1 55822188 3167175 205933..207795 1 NC_006449.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 207795 proS 3167175 proS Streptococcus thermophilus CNRZ1066 prolyl-tRNA synthetase YP_140629.1 205933 D 299768 CDS YP_140630.1 55822189 3167165 208373..210352 1 NC_006449.1 ABC transporter permease 210352 3167165 str0201 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_140630.1 208373 D 299768 CDS YP_140631.1 55822190 3167124 210352..211155 1 NC_006449.1 ABC transporter ATP binding protein 211155 3167124 str0202 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140631.1 210352 D 299768 CDS YP_140632.2 161936383 3167094 211323..211610 1 NC_006449.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 211610 groES 3167094 groES Streptococcus thermophilus CNRZ1066 co-chaperonin GroES YP_140632.2 211323 D 299768 CDS YP_140633.1 55822192 3167089 211659..213278 1 NC_006449.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 213278 groEL 3167089 groEL Streptococcus thermophilus CNRZ1066 molecular chaperone GroEL YP_140633.1 211659 D 299768 CDS YP_140634.1 55822193 3167155 213372..213830 1 NC_006449.1 truncated; hypothetical protein 213830 3167155 str0205 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140634.1 213372 D 299768 CDS YP_140635.1 55822194 3167534 213884..214216 1 NC_006449.1 truncated; hypothetical protein 214216 3167534 str0206 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140635.1 213884 D 299768 CDS YP_140636.1 55822195 3167213 214274..214492 1 NC_006449.1 truncated; hypothetical protein 214492 3167213 str0207 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140636.1 214274 D 299768 CDS YP_140637.1 55822196 3166722 complement(214685..214912) 1 NC_006449.1 hypothetical protein 214912 3166722 str0208 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140637.1 214685 R 299768 CDS YP_140638.1 55822197 3167171 complement(215503..215808) 1 NC_006449.1 hypothetical protein 215808 3167171 str0209 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140638.1 215503 R 299768 CDS YP_140639.1 55822198 3167044 complement(215808..215999) 1 NC_006449.1 hypothetical protein 215999 3167044 str0210 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140639.1 215808 R 299768 CDS YP_140640.1 55822199 3167209 complement(216319..217191) 1 NC_006449.1 ribosomal large subunit pseudouridine synthase D 217191 3167209 str0211 Streptococcus thermophilus CNRZ1066 ribosomal large subunit pseudouridine synthase D YP_140640.1 216319 R 299768 CDS YP_140641.1 55822200 3165996 217257..219584 1 NC_006449.1 penicillin-binding protein 2A 219584 pbp2A 3165996 pbp2A Streptococcus thermophilus CNRZ1066 penicillin-binding protein 2A YP_140641.1 217257 D 299768 CDS YP_140642.1 55822201 3167290 219633..219785 1 NC_006449.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 219785 rpmG 3167290 rpmG Streptococcus thermophilus CNRZ1066 50S ribosomal protein L33 YP_140642.1 219633 D 299768 CDS YP_140643.1 55822202 3167128 219794..219970 1 NC_006449.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 219970 secE 3167128 secE Streptococcus thermophilus CNRZ1066 preprotein translocase subunit SecE YP_140643.1 219794 D 299768 CDS YP_140644.1 55822203 3166941 220167..220706 1 NC_006449.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 220706 nusG 3166941 nusG Streptococcus thermophilus CNRZ1066 transcription antitermination protein NusG YP_140644.1 220167 D 299768 CDS YP_140645.1 55822204 3167075 220828..221316 1 NC_006449.1 hypothetical protein 221316 3167075 str0216 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140645.1 220828 D 299768 CDS YP_140646.1 55822205 3166986 complement(221448..221789) 1 NC_006449.1 truncated; hypothetical protein 221789 3166986 str0217 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140646.1 221448 R 299768 CDS YP_140647.1 55822206 3167161 complement(222042..222278) 1 NC_006449.1 truncated; hypothetical protein 222278 3167161 str0218 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140647.1 222042 R 299768 CDS YP_140648.1 55822207 3167160 complement(222253..223017) 1 NC_006449.1 DeoR family transcriptional regulator 223017 3167160 str0219 Streptococcus thermophilus CNRZ1066 DeoR family transcriptional regulator YP_140648.1 222253 R 299768 CDS YP_140649.1 55822208 3167536 223191..225692 1 NC_006449.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 225692 leuS 3167536 leuS Streptococcus thermophilus CNRZ1066 leucyl-tRNA synthetase YP_140649.1 223191 D 299768 CDS YP_140650.1 55822209 3167211 225781..225972 1 NC_006449.1 hypothetical protein 225972 3167211 str0221 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140650.1 225781 D 299768 CDS YP_140651.1 55822210 3167042 226003..226140 1 NC_006449.1 hypothetical protein 226140 3167042 str0222 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140651.1 226003 D 299768 CDS YP_140652.1 55822211 3167138 complement(226461..227459) 1 NC_006449.1 IS1239 transposase 227459 tnp1239 3167138 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_140652.1 226461 R 299768 CDS YP_140653.1 55822212 3167151 227646..228158 1 NC_006449.1 truncated; acyl-CoA thioesterase 228158 3167151 str0224 Streptococcus thermophilus CNRZ1066 acyl-CoA thioesterase YP_140653.1 227646 D 299768 CDS YP_140654.1 55822213 3167176 228109..228867 1 NC_006449.1 truncated; acyl-CoA thioesterase 228867 3167176 str0225 Streptococcus thermophilus CNRZ1066 acyl-CoA thioesterase YP_140654.1 228109 D 299768 CDS YP_140655.2 161936382 3166001 229161..230615 1 NC_006449.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 230615 pncB 3166001 pncB Streptococcus thermophilus CNRZ1066 nicotinate phosphoribosyltransferase YP_140655.2 229161 D 299768 CDS YP_140656.1 55822215 3167202 230627..231448 1 NC_006449.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 231448 nadE 3167202 nadE Streptococcus thermophilus CNRZ1066 NAD synthetase YP_140656.1 230627 D 299768 CDS YP_140657.1 55822216 3167216 231464..231904 1 NC_006449.1 hypothetical protein 231904 3167216 str0228 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140657.1 231464 D 299768 CDS YP_140658.1 55822217 3167289 232006..233343 1 NC_006449.1 cysteine aminopeptidase 233343 pepC 3167289 pepC Streptococcus thermophilus CNRZ1066 cysteine aminopeptidase YP_140658.1 232006 D 299768 CDS YP_140659.1 55822218 3167529 complement(233453..235816) 1 NC_006449.1 penicillin-binding protein 1A 235816 pbp1A 3167529 pbp1A Streptococcus thermophilus CNRZ1066 penicillin-binding protein 1A YP_140659.1 233453 R 299768 CDS YP_140660.1 55822219 3167092 complement(235816..236412) 1 NC_006449.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 236412 recU 3167092 recU Streptococcus thermophilus CNRZ1066 Holliday junction-specific endonuclease YP_140660.1 235816 R 299768 CDS YP_140661.1 55822220 3166976 236489..237004 1 NC_006449.1 hypothetical protein 237004 3166976 str0232 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140661.1 236489 D 299768 CDS YP_140662.1 55822221 3167191 237113..237445 1 NC_006449.1 GpsB; guiding PBP1 shuttling; similar to DivIVA; cell division protein GpsB 237445 3167191 str0233 Streptococcus thermophilus CNRZ1066 cell division protein GpsB YP_140662.1 237113 D 299768 CDS YP_140663.1 55822222 3167088 237972..239144 1 NC_006449.1 hypothetical protein 239144 3167088 str0234 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140663.1 237972 D 299768 CDS YP_140664.1 55822223 3167120 239147..241009 1 NC_006449.1 hypothetical protein 241009 3167120 str0235 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140664.1 239147 D 299768 CDS YP_140665.1 55822224 3167286 241237..242235 1 NC_006449.1 IS1239 transposase 242235 tnp1239 3167286 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_140665.1 241237 D 299768 CDS YP_140666.1 55822225 3167106 242365..245460 1 NC_006449.1 ATP-dependent RNA helicase 245460 snf 3167106 snf Streptococcus thermophilus CNRZ1066 ATP-dependent RNA helicase YP_140666.1 242365 D 299768 CDS YP_140667.1 55822226 3167189 245616..246332 1 NC_006449.1 hypothetical protein 246332 3167189 str0238 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140667.1 245616 D 299768 CDS YP_140668.1 55822227 3167267 246344..247687 1 NC_006449.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 247687 murC 3167267 murC Streptococcus thermophilus CNRZ1066 UDP-N-acetylmuramate--L-alanine ligase YP_140668.1 246344 D 299768 CDS YP_140669.1 55822228 3167028 247788..248132 1 NC_006449.1 acetyltransferase 248132 3167028 str0240 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_140669.1 247788 D 299768 CDS YP_140670.1 55822229 3167199 248340..250316 1 NC_006449.1 aminodeoxychorismate lyase 250316 pabC 3167199 pabC Streptococcus thermophilus CNRZ1066 aminodeoxychorismate lyase YP_140670.1 248340 D 299768 CDS YP_140671.1 55822230 3167201 250400..250882 1 NC_006449.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 250882 greA 3167201 greA Streptococcus thermophilus CNRZ1066 transcription elongation factor GreA YP_140671.1 250400 D 299768 CDS YP_140672.1 55822231 3166711 251287..251775 1 NC_006449.1 truncated; hypothetical protein 251775 3166711 str0244 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140672.1 251287 D 299768 CDS YP_140673.1 55822232 3167114 complement(251831..252748) 1 NC_006449.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 252748 3167114 str0245 Streptococcus thermophilus CNRZ1066 OxaA-like protein precursor YP_140673.1 251831 R 299768 CDS YP_140674.1 55822233 3167284 complement(252835..253113) 1 NC_006449.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 253113 acyP 3167284 acyP Streptococcus thermophilus CNRZ1066 acylphosphatase YP_140674.1 252835 R 299768 CDS YP_140675.1 55822234 3167162 253216..253953 1 NC_006449.1 rRNA methyltransferase 253953 spoU 3167162 spoU Streptococcus thermophilus CNRZ1066 rRNA methyltransferase YP_140675.1 253216 D 299768 CDS YP_140676.1 55822235 3167137 254055..254549 1 NC_006449.1 hydrolase 254549 3167137 str0248 Streptococcus thermophilus CNRZ1066 hydrolase YP_140676.1 254055 D 299768 CDS YP_140677.1 55822236 3167145 254583..255272 1 NC_006449.1 hypothetical protein 255272 3167145 str0249 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140677.1 254583 D 299768 CDS YP_140678.1 55822237 3167485 complement(255447..255647) 1 NC_006449.1 hypothetical protein 255647 3167485 str0250 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140678.1 255447 R 299768 CDS YP_140679.1 55822238 3167185 complement(256055..256393) 1 NC_006449.1 hypothetical protein 256393 3167185 str0251 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140679.1 256055 R 299768 CDS YP_140680.1 55822239 3166985 256568..257833 1 NC_006449.1 diaminopimelate decarboxylase 257833 lysA 3166985 lysA Streptococcus thermophilus CNRZ1066 diaminopimelate decarboxylase YP_140680.1 256568 D 299768 CDS YP_140681.1 55822240 3167083 complement(257863..258402) 1 NC_006449.1 TetR/AcrR family transcriptional regulator 258402 3167083 str0253 Streptococcus thermophilus CNRZ1066 TetR/AcrR family transcriptional regulator YP_140681.1 257863 R 299768 CDS YP_140682.1 55822241 3166968 258643..258888 1 NC_006449.1 hypothetical protein 258888 3166968 str0254 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140682.1 258643 D 299768 CDS YP_140683.1 55822242 3167277 258954..259769 1 NC_006449.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 259769 glr 3167277 glr Streptococcus thermophilus CNRZ1066 glutamate racemase YP_140683.1 258954 D 299768 CDS YP_140684.1 55822243 3167210 259762..260736 1 NC_006449.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein 260736 3167210 str0256 Streptococcus thermophilus CNRZ1066 deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein YP_140684.1 259762 D 299768 CDS YP_140685.1 55822244 3167188 260718..261239 1 NC_006449.1 hypothetical protein 261239 3167188 str0257 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140685.1 260718 D 299768 CDS YP_140686.1 55822245 3167118 261236..261718 1 NC_006449.1 hypothetical protein 261718 3167118 str0258 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140686.1 261236 D 299768 CDS YP_140687.1 55822246 3167183 261672..262433 1 NC_006449.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 262433 xerD 3167183 xerD Streptococcus thermophilus CNRZ1066 site-specific tyrosine recombinase XerD-like protein YP_140687.1 261672 D 299768 CDS YP_140688.1 55822247 3167272 262433..263146 1 NC_006449.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 263146 scpA 3167272 scpA Streptococcus thermophilus CNRZ1066 segregation and condensation protein A YP_140688.1 262433 D 299768 CDS YP_140689.1 55822248 3167280 263139..263720 1 NC_006449.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 263720 scpB 3167280 scpB Streptococcus thermophilus CNRZ1066 segregation and condensation protein B YP_140689.1 263139 D 299768 CDS YP_140690.1 55822249 3167294 263771..264538 1 NC_006449.1 ribosomal large subunit pseudouridine synthase B 264538 rluB 3167294 rluB Streptococcus thermophilus CNRZ1066 ribosomal large subunit pseudouridine synthase B YP_140690.1 263771 D 299768 CDS YP_140691.1 55822250 3167131 264535..264786 1 NC_006449.1 hypothetical protein 264786 3167131 str0263 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140691.1 264535 D 299768 CDS YP_140692.1 55822251 3166497 complement(264809..266248) 1 NC_006449.1 potassium Trk transporter membrane-spanning protein 266248 trkH1 3166497 trkH1 Streptococcus thermophilus CNRZ1066 potassium Trk transporter membrane-spanning protein YP_140692.1 264809 R 299768 CDS YP_140693.1 55822252 3166007 complement(266255..267604) 1 NC_006449.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 267604 trkA 3166007 trkA Streptococcus thermophilus CNRZ1066 potassium transporter peripheral membrane component YP_140693.1 266255 R 299768 CDS YP_140694.1 55822253 3167157 267848..268402 1 NC_006449.1 rRNA methyltransferase 268402 3167157 str0267 Streptococcus thermophilus CNRZ1066 rRNA methyltransferase YP_140694.1 267848 D 299768 CDS YP_140695.1 55822254 3166669 268636..269271 1 NC_006449.1 hypothetical protein 269271 3166669 str0268 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140695.1 268636 D 299768 CDS YP_140696.1 55822255 3166009 269274..269924 1 NC_006449.1 hypothetical protein 269924 3166009 str0269 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140696.1 269274 D 299768 CDS YP_140697.1 55822256 3167214 270119..271018 1 NC_006449.1 transcriptional regulator 271018 plcR 3167214 plcR Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140697.1 270119 D 299768 CDS YP_140698.1 55822257 3167253 271194..271418 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein/permease 271418 3167253 str0271 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140698.1 271194 D 299768 CDS YP_140699.1 55822258 3167057 271449..272114 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein/permease 272114 3167057 str0272 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140699.1 271449 D 299768 CDS YP_140700.1 55822259 3167197 272145..272435 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein/permease 272435 3167197 str0273 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140700.1 272145 D 299768 CDS YP_140701.1 55822260 3167182 272457..272891 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein/permease 272891 3167182 str0274 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140701.1 272457 D 299768 CDS YP_140702.1 55822261 3166943 272870..273289 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein/permease 273289 3166943 str0275 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140702.1 272870 D 299768 CDS YP_140703.1 55822262 3167261 273397..273708 1 NC_006449.1 hypothetical protein 273708 3167261 str0276 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140703.1 273397 D 299768 CDS YP_140704.1 55822263 3166012 complement(273676..273957) 1 NC_006449.1 truncated; urease cluster protein, truncated 273957 3166012 str0277 Streptococcus thermophilus CNRZ1066 urease cluster protein, truncated YP_140704.1 273676 R 299768 CDS YP_140705.1 55822264 3167187 complement(274200..274502) 1 NC_006449.1 truncated; urease cluster protein, truncated 274502 3167187 str0278 Streptococcus thermophilus CNRZ1066 urease cluster protein, truncated YP_140705.1 274200 R 299768 CDS YP_140706.1 55822265 3166961 complement(274726..275160) 1 NC_006449.1 truncated; urease cluster protein, truncated 275160 3166961 str0279 Streptococcus thermophilus CNRZ1066 urease cluster protein, truncated YP_140706.1 274726 R 299768 CDS YP_140707.1 55822266 3167226 275502..276017 1 NC_006449.1 urease accessory protein 276017 ureI 3167226 ureI Streptococcus thermophilus CNRZ1066 urease accessory protein YP_140707.1 275502 D 299768 CDS YP_140708.1 55822267 3165864 276042..276344 1 NC_006449.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 276344 ureA 3165864 ureA Streptococcus thermophilus CNRZ1066 urease subunit gamma YP_140708.1 276042 D 299768 CDS YP_140709.1 55822268 3167069 276356..276667 1 NC_006449.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 276667 ureB 3167069 ureB Streptococcus thermophilus CNRZ1066 urease subunit beta YP_140709.1 276356 D 299768 CDS YP_140710.1 55822269 3167116 276683..278401 1 NC_006449.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 278401 ureC 3167116 ureC Streptococcus thermophilus CNRZ1066 urease subunit alpha YP_140710.1 276683 D 299768 CDS YP_140711.1 55822270 3167090 278542..278994 1 NC_006449.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 278994 ureE 3167090 ureE Streptococcus thermophilus CNRZ1066 urease accessory protein UreE YP_140711.1 278542 D 299768 CDS YP_140712.1 55822271 3166147 278984..279697 1 NC_006449.1 urease accessory protein 279697 ureF 3166147 ureF Streptococcus thermophilus CNRZ1066 urease accessory protein YP_140712.1 278984 D 299768 CDS YP_140713.1 55822272 3166861 279727..280341 1 NC_006449.1 urease accessory protein 280341 ureG 3166861 ureG Streptococcus thermophilus CNRZ1066 urease accessory protein YP_140713.1 279727 D 299768 CDS YP_140714.1 55822273 3166988 280343..281182 1 NC_006449.1 urease accessory protein 281182 ureD 3166988 ureD Streptococcus thermophilus CNRZ1066 urease accessory protein YP_140714.1 280343 D 299768 CDS YP_140715.1 55822274 3167250 281186..282163 1 NC_006449.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 282163 cbiM 3167250 cbiM Streptococcus thermophilus CNRZ1066 cobalt transport protein CbiM YP_140715.1 281186 D 299768 CDS YP_140716.1 55822275 3167172 282160..282939 1 NC_006449.1 cobalt ABC transporter permease 282939 cbiQ 3167172 cbiQ Streptococcus thermophilus CNRZ1066 cobalt ABC transporter permease YP_140716.1 282160 D 299768 CDS YP_140717.1 55822276 3167108 282941..283654 1 NC_006449.1 cobalt ABC transporter ATP-binding protein 283654 cbiO 3167108 cbiO Streptococcus thermophilus CNRZ1066 cobalt ABC transporter ATP-binding protein YP_140717.1 282941 D 299768 CDS YP_140718.1 55822277 3167266 283820..284668 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 284668 3167266 str0296 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_140718.1 283820 D 299768 CDS YP_140719.1 55822278 3167245 284828..285730 1 NC_006449.1 ABC transporter substrate binding protein 285730 3167245 str0297 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein YP_140719.1 284828 D 299768 CDS YP_140720.1 55822279 3167097 285791..286273 1 NC_006449.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 286273 3167097 str0298 Streptococcus thermophilus CNRZ1066 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_140720.1 285791 D 299768 CDS YP_140721.1 55822280 3166938 286331..286696 1 NC_006449.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 286696 3166938 str0299 Streptococcus thermophilus CNRZ1066 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_140721.1 286331 D 299768 CDS YP_140722.1 55822281 3167156 286781..287164 1 NC_006449.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 287164 3167156 str0300 Streptococcus thermophilus CNRZ1066 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_140722.1 286781 D 299768 CDS YP_140723.1 55822282 3166017 287157..288224 1 NC_006449.1 ABC transporter ATP binding protein 288224 3166017 str0301 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140723.1 287157 D 299768 CDS YP_140724.1 55822283 3167139 288224..288916 1 NC_006449.1 ABC transporter permease 288916 3167139 str0302 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_140724.1 288224 D 299768 CDS YP_140725.1 55822284 3167164 289039..290247 1 NC_006449.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 290247 dctA 3167164 dctA Streptococcus thermophilus CNRZ1066 serine/threonine transporter SstT YP_140725.1 289039 D 299768 CDS YP_140726.1 55822285 3167135 290401..291249 1 NC_006449.1 hypothetical protein 291249 3167135 str0304 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140726.1 290401 D 299768 CDS YP_140727.1 55822286 3166964 291259..291804 1 NC_006449.1 hypothetical protein 291804 3166964 str0306 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140727.1 291259 D 299768 CDS YP_140728.1 55822287 3167112 291840..293546 1 NC_006449.1 ABC transporter ATP binding protein 293546 3167112 str0308 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140728.1 291840 D 299768 CDS YP_140729.1 55822288 3167133 293539..294369 1 NC_006449.1 ABC transporter permease 294369 3167133 str0310 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_140729.1 293539 D 299768 CDS YP_140730.1 55822289 3167248 294579..296555 1 NC_006449.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 296555 tkt 3167248 tkt Streptococcus thermophilus CNRZ1066 transketolase YP_140730.1 294579 D 299768 CDS YP_140731.1 55822290 3167086 complement(296804..297475) 1 NC_006449.1 potassium Trk transporter NAD+ binding protein 297475 trkA2 3167086 trkA2 Streptococcus thermophilus CNRZ1066 potassium Trk transporter NAD+ binding protein YP_140731.1 296804 R 299768 CDS YP_140732.1 55822291 3167087 complement(297515..298900) 1 NC_006449.1 potassium Trk transporter membrane-spanning protein 298900 trkH2 3167087 trkH2 Streptococcus thermophilus CNRZ1066 potassium Trk transporter membrane-spanning protein YP_140732.1 297515 R 299768 CDS YP_140733.1 55822292 3166018 complement(298949..299662) 1 NC_006449.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 299662 gidB 3166018 gidB Streptococcus thermophilus CNRZ1066 16S rRNA methyltransferase GidB YP_140733.1 298949 R 299768 CDS YP_140734.1 55822293 3167275 299953..300495 1 NC_006449.1 hypothetical protein 300495 3167275 str0316 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140734.1 299953 D 299768 CDS YP_140735.1 55822294 3167252 300651..301340 1 NC_006449.1 response regulator 301340 rr01 3167252 rr01 Streptococcus thermophilus CNRZ1066 response regulator YP_140735.1 300651 D 299768 CDS YP_140736.1 55822295 3167169 301337..302854 1 NC_006449.1 sensor histidine kinase CsrS/CovS-like protein 302854 hk01 3167169 hk01 Streptococcus thermophilus CNRZ1066 sensor histidine kinase CsrS/CovS-like protein YP_140736.1 301337 D 299768 CDS YP_140737.2 161936381 3167096 302976..303455 1 NC_006449.1 transcriptional regulator NrdR 303455 nrdR 3167096 nrdR Streptococcus thermophilus CNRZ1066 transcriptional regulator NrdR YP_140737.2 302976 D 299768 CDS YP_140738.1 55822297 3166024 303452..304627 1 NC_006449.1 chromosome replication initiation / membrane attachment protein DnaB 304627 dnaB 3166024 dnaB Streptococcus thermophilus CNRZ1066 chromosome replication initiation / membrane attachment protein DnaB YP_140738.1 303452 D 299768 CDS YP_140739.1 55822298 3167225 304631..305533 1 NC_006449.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 305533 dnaI 3167225 dnaI Streptococcus thermophilus CNRZ1066 primosomal protein DnaI YP_140739.1 304631 D 299768 CDS YP_140740.1 55822299 3167229 305639..306949 1 NC_006449.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 306949 engA 3167229 engA Streptococcus thermophilus CNRZ1066 GTP-binding protein EngA YP_140740.1 305639 D 299768 CDS YP_140741.1 55822300 3166026 307086..307343 1 NC_006449.1 hypothetical protein 307343 3166026 str0323 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140741.1 307086 D 299768 CDS YP_140742.1 55822301 3167159 complement(308136..309725) 1 NC_006449.1 peptide ABC transporter ATP-binding protein/permease 309725 3167159 str0324 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_140742.1 308136 R 299768 CDS YP_140743.1 55822302 3165834 complement(309709..310497) 1 NC_006449.1 hypothetical protein 310497 3165834 str0325 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140743.1 309709 R 299768 CDS YP_140744.1 55822303 3167198 310669..311043 1 NC_006449.1 truncated; truncated IS1191 transposase 311043 3167198 str0326 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_140744.1 310669 D 299768 CDS YP_140745.1 55822304 3167489 311060..311866 1 NC_006449.1 truncated; truncated IS1191 transposase 311866 3167489 str0327 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_140745.1 311060 D 299768 CDS YP_140746.1 55822305 3167130 complement(311913..312146) 1 NC_006449.1 hypothetical protein 312146 3167130 str0328 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140746.1 311913 R 299768 CDS YP_140747.2 161936380 3166949 complement(312509..313786) 1 NC_006449.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 313786 serS 3166949 serS Streptococcus thermophilus CNRZ1066 seryl-tRNA synthetase YP_140747.2 312509 R 299768 CDS YP_140748.1 55822307 3167166 complement(313995..314369) 1 NC_006449.1 hypothetical protein 314369 3167166 str0330 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140748.1 313995 R 299768 CDS YP_140749.1 55822308 3167070 complement(314448..315359) 1 NC_006449.1 PTS system mannose transporter subunit IID 315359 manN 3167070 manN Streptococcus thermophilus CNRZ1066 PTS system mannose transporter subunit IID YP_140749.1 314448 R 299768 CDS YP_140750.1 55822309 3167244 complement(315374..316201) 1 NC_006449.1 PTS system mannose transporter subunit IIC 316201 manM 3167244 manM Streptococcus thermophilus CNRZ1066 PTS system mannose transporter subunit IIC YP_140750.1 315374 R 299768 CDS YP_140751.1 55822310 3167203 complement(316269..317261) 1 NC_006449.1 PTS system mannose transporter subunit IIAB 317261 manL 3167203 manL Streptococcus thermophilus CNRZ1066 PTS system mannose transporter subunit IIAB YP_140751.1 316269 R 299768 CDS YP_140752.1 55822311 3167141 317637..318431 1 NC_006449.1 hypothetical protein 318431 3167141 str0334 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140752.1 317637 D 299768 CDS YP_140753.1 55822312 3166135 complement(318413..319249) 1 NC_006449.1 hypothetical protein 319249 3166135 str0335 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140753.1 318413 R 299768 CDS YP_140754.1 55822313 3165836 319434..320855 1 NC_006449.1 hypothetical protein 320855 3165836 str0336 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140754.1 319434 D 299768 CDS YP_140755.1 55822314 3166059 321127..321570 1 NC_006449.1 hypothetical protein 321570 3166059 str0337 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140755.1 321127 D 299768 CDS YP_140756.1 55822315 3167271 321563..322084 1 NC_006449.1 acetyltransferase 322084 3167271 str0338 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_140756.1 321563 D 299768 CDS YP_140757.1 55822316 3167207 322093..323319 1 NC_006449.1 transcriptional regulator 323319 3167207 str0339 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140757.1 322093 D 299768 CDS YP_140758.1 55822317 3166266 323442..323933 1 NC_006449.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 323933 3166266 str0340 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140758.1 323442 D 299768 CDS YP_140759.1 55822318 3165980 323999..325186 1 NC_006449.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 325186 nusA 3165980 nusA Streptococcus thermophilus CNRZ1066 transcription elongation factor NusA YP_140759.1 323999 D 299768 CDS YP_140760.1 55822319 3166952 325204..325503 1 NC_006449.1 hypothetical protein 325503 3166952 str0342 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140760.1 325204 D 299768 CDS YP_140761.1 55822320 3166354 325496..325798 1 NC_006449.1 hypothetical protein 325798 3166354 str0343 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140761.1 325496 D 299768 CDS YP_140762.1 55822321 3167080 325817..328648 1 NC_006449.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 328648 infB 3167080 infB Streptococcus thermophilus CNRZ1066 translation initiation factor IF-2 YP_140762.1 325817 D 299768 CDS YP_140763.1 55822322 3167163 328742..329095 1 NC_006449.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 329095 rbfA 3167163 rbfA Streptococcus thermophilus CNRZ1066 ribosome-binding factor A YP_140763.1 328742 D 299768 CDS YP_140764.1 55822323 3167235 329160..329333 1 NC_006449.1 truncated; hypothetical protein 329333 3167235 str0346 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140764.1 329160 D 299768 CDS YP_140765.1 55822324 3167066 329346..329615 1 NC_006449.1 truncated; hypothetical protein 329615 3167066 str0347 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140765.1 329346 D 299768 CDS YP_140766.1 55822325 3167535 329989..331248 1 NC_006449.1 peptidoglycan branched peptide synthesis protein, alanine adding enzyme 331248 murO 3167535 murO Streptococcus thermophilus CNRZ1066 peptidoglycan branched peptide synthesis protein, alanine adding enzyme YP_140766.1 329989 D 299768 CDS YP_140767.1 55822326 3165870 complement(331317..332762) 1 NC_006449.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 332762 murE 3165870 murE Streptococcus thermophilus CNRZ1066 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_140767.1 331317 R 299768 CDS YP_140768.1 55822327 3165857 332857..334488 1 NC_006449.1 polysaccharide transporter 334488 3165857 str0350 Streptococcus thermophilus CNRZ1066 polysaccharide transporter YP_140768.1 332857 D 299768 CDS YP_140769.1 55822328 3165684 334512..335021 1 NC_006449.1 truncated; cation transporter P-type ATPase, truncated 335021 3165684 str0351 Streptococcus thermophilus CNRZ1066 cation transporter P-type ATPase, truncated YP_140769.1 334512 D 299768 CDS YP_140770.1 55822329 3166541 335428..336522 1 NC_006449.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 336522 metB1 3166541 metB1 Streptococcus thermophilus CNRZ1066 cystathionine gamma-synthase YP_140770.1 335428 D 299768 CDS YP_140771.1 55822330 3165931 336491..337696 1 NC_006449.1 class II aminotransferase 337696 3165931 str0353 Streptococcus thermophilus CNRZ1066 class II aminotransferase YP_140771.1 336491 D 299768 CDS YP_140772.1 55822331 3167283 337812..338114 1 NC_006449.1 hypothetical protein 338114 3167283 str0354 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140772.1 337812 D 299768 CDS YP_140773.1 55822332 3167193 338384..339013 1 NC_006449.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 339013 upp 3167193 upp Streptococcus thermophilus CNRZ1066 uracil phosphoribosyltransferase YP_140773.1 338384 D 299768 CDS YP_140774.1 55822333 3167100 339151..339741 1 NC_006449.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 339741 clpP 3167100 clpP Streptococcus thermophilus CNRZ1066 ATP-dependent Clp protease proteolytic subunit YP_140774.1 339151 D 299768 CDS YP_140775.1 55822334 3167150 339828..340277 1 NC_006449.1 hypothetical protein 340277 3167150 str0357 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140775.1 339828 D 299768 CDS YP_140776.1 55822335 3166233 340270..340551 1 NC_006449.1 hypothetical protein 340551 3166233 str0358 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140776.1 340270 D 299768 CDS YP_140777.1 55822336 3167281 340708..341883 1 NC_006449.1 branched-chain amino acid ABC transporter substrate-binding protein 341883 livJ 3167281 livJ Streptococcus thermophilus CNRZ1066 branched-chain amino acid ABC transporter substrate-binding protein YP_140777.1 340708 D 299768 CDS YP_140778.1 55822337 3166955 341927..342811 1 NC_006449.1 branched-chain amino acid ABC transporter permease 342811 livH 3166955 livH Streptococcus thermophilus CNRZ1066 branched-chain amino acid ABC transporter permease YP_140778.1 341927 D 299768 CDS YP_140779.1 55822338 3166557 342815..343765 1 NC_006449.1 branched-chain amino acid ABC transporter permease 343765 livM 3166557 livM Streptococcus thermophilus CNRZ1066 branched-chain amino acid ABC transporter permease YP_140779.1 342815 D 299768 CDS YP_140780.1 55822339 3165895 343768..344532 1 NC_006449.1 branched-chain amino acid ABC transporter ATP binding protein 344532 livG 3165895 livG Streptococcus thermophilus CNRZ1066 branched-chain amino acid ABC transporter ATP binding protein YP_140780.1 343768 D 299768 CDS YP_140781.1 55822340 3167537 344532..345242 1 NC_006449.1 branched chain amino acid ABC transporter ATP binding protein 345242 livF 3167537 livF Streptococcus thermophilus CNRZ1066 branched chain amino acid ABC transporter ATP binding protein YP_140781.1 344532 D 299768 CDS YP_140782.1 55822341 3167154 345396..345815 1 NC_006449.1 truncated; acetoin utilization protein, truncated 345815 3167154 str0364 Streptococcus thermophilus CNRZ1066 acetoin utilization protein, truncated YP_140782.1 345396 D 299768 CDS YP_140783.1 55822342 3167119 345760..346038 1 NC_006449.1 truncated; acetoin utilization protein, truncated 346038 3167119 str0365 Streptococcus thermophilus CNRZ1066 acetoin utilization protein, truncated YP_140783.1 345760 D 299768 CDS YP_140784.1 55822343 3165933 complement(346205..347137) 1 NC_006449.1 cysteine synthase 347137 cysM1 3165933 cysM1 Streptococcus thermophilus CNRZ1066 cysteine synthase YP_140784.1 346205 R 299768 CDS YP_140785.1 55822344 3167153 complement(347233..347859) 1 NC_006449.1 hypothetical protein 347859 3167153 str0367 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140785.1 347233 R 299768 CDS YP_140786.1 55822345 3167186 347914..349233 1 NC_006449.1 late competence protein required for DNA uptake 349233 comFA 3167186 comFA Streptococcus thermophilus CNRZ1066 late competence protein required for DNA uptake YP_140786.1 347914 D 299768 CDS YP_140787.1 55822346 3166084 349208..349876 1 NC_006449.1 late competence protein 349876 comFC 3166084 comFC Streptococcus thermophilus CNRZ1066 late competence protein YP_140787.1 349208 D 299768 CDS YP_140788.1 55822347 3166870 349955..350503 1 NC_006449.1 ribosomal protein S30AE family protein 350503 3166870 str0370 Streptococcus thermophilus CNRZ1066 ribosomal protein S30AE family protein YP_140788.1 349955 D 299768 CDS YP_140789.1 55822348 3166440 complement(350533..351531) 1 NC_006449.1 IS1239 transposase 351531 tnp1239 3166440 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_140789.1 350533 R 299768 CDS YP_140790.1 55822349 3167251 357660..358592 1 NC_006449.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 358592 ppaC 3167251 ppaC Streptococcus thermophilus CNRZ1066 manganese-dependent inorganic pyrophosphatase YP_140790.1 357660 D 299768 CDS YP_140791.1 55822350 3167147 358646..359305 1 NC_006449.1 hypothetical protein 359305 3167147 str0373 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140791.1 358646 D 299768 CDS YP_140792.1 55822351 3166927 complement(359335..359868) 1 NC_006449.1 hypothetical protein 359868 3166927 str0374 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140792.1 359335 R 299768 CDS YP_140793.1 55822352 3167239 complement(359939..360715) 1 NC_006449.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 360715 recX 3167239 recX Streptococcus thermophilus CNRZ1066 recombination regulator RecX YP_140793.1 359939 R 299768 CDS YP_140794.1 55822353 3167024 360750..362114 1 NC_006449.1 TrmA family tRNA methyltransferase 362114 3167024 str0376 Streptococcus thermophilus CNRZ1066 TrmA family tRNA methyltransferase YP_140794.1 360750 D 299768 CDS YP_140795.1 55822354 3167158 362213..363205 1 NC_006449.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 363205 asnA 3167158 asnA Streptococcus thermophilus CNRZ1066 asparagine synthetase AsnA YP_140795.1 362213 D 299768 CDS YP_140796.1 55822355 3165839 complement(363357..364715) 1 NC_006449.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 364715 lysC 3165839 lysC Streptococcus thermophilus CNRZ1066 aspartate kinase YP_140796.1 363357 R 299768 CDS YP_140797.1 55822356 3166848 364847..365485 1 NC_006449.1 beta-phosphoglucomutase 365485 3166848 str0379 Streptococcus thermophilus CNRZ1066 beta-phosphoglucomutase YP_140797.1 364847 D 299768 CDS YP_140798.1 55822357 3167274 365767..366489 1 NC_006449.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 366489 phaB 3167274 phaB Streptococcus thermophilus CNRZ1066 enoyl-CoA hydratase YP_140798.1 365767 D 299768 CDS YP_140799.1 55822358 3167129 366593..367027 1 NC_006449.1 MarR family transcriptional regulator 367027 3167129 str0381 Streptococcus thermophilus CNRZ1066 MarR family transcriptional regulator YP_140799.1 366593 D 299768 CDS YP_140800.1 55822359 3167494 367027..367989 1 NC_006449.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 367989 fabH 3167494 fabH Streptococcus thermophilus CNRZ1066 3-oxoacyl-ACP synthase YP_140800.1 367027 D 299768 CDS YP_140801.1 55822360 3167050 368053..368277 1 NC_006449.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 368277 acpP 3167050 acpP Streptococcus thermophilus CNRZ1066 acyl carrier protein YP_140801.1 368053 D 299768 CDS YP_140802.1 55822361 3166911 368382..369347 1 NC_006449.1 trans-2-enoyl-ACP reductase II 369347 fabK 3166911 fabK Streptococcus thermophilus CNRZ1066 trans-2-enoyl-ACP reductase II YP_140802.1 368382 D 299768 CDS YP_140803.1 55822362 3166738 369364..370290 1 NC_006449.1 ACP S-malonyltransferase 370290 fabD 3166738 fabD Streptococcus thermophilus CNRZ1066 ACP S-malonyltransferase YP_140803.1 369364 D 299768 CDS YP_140804.1 55822363 3167174 370303..371037 1 NC_006449.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 371037 fabG 3167174 fabG Streptococcus thermophilus CNRZ1066 3-ketoacyl-ACP reductase YP_140804.1 370303 D 299768 CDS YP_140805.1 55822364 3166545 371099..372331 1 NC_006449.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 372331 fabF 3166545 fabF Streptococcus thermophilus CNRZ1066 3-oxoacyl-ACP synthase YP_140805.1 371099 D 299768 CDS YP_140806.1 55822365 3166925 372335..372823 1 NC_006449.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 372823 accB 3166925 accB Streptococcus thermophilus CNRZ1066 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_140806.1 372335 D 299768 CDS YP_140807.1 55822366 3167236 372820..373245 1 NC_006449.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 373245 fabZ 3167236 fabZ Streptococcus thermophilus CNRZ1066 (3R)-hydroxymyristoyl-ACP dehydratase YP_140807.1 372820 D 299768 CDS YP_140808.2 161936379 3166596 373365..374735 1 NC_006449.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 374735 accC 3166596 accC Streptococcus thermophilus CNRZ1066 acetyl-CoA carboxylase biotin carboxylase subunit YP_140808.2 373365 D 299768 CDS YP_140809.1 55822368 3165653 374741..375607 1 NC_006449.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 375607 accD 3165653 accD Streptococcus thermophilus CNRZ1066 acetyl-CoA carboxylase subunit beta YP_140809.1 374741 D 299768 CDS YP_140810.1 55822369 3166208 375604..376374 1 NC_006449.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 376374 accA 3166208 accA Streptococcus thermophilus CNRZ1066 acetyl-CoA carboxylase subunit alpha YP_140810.1 375604 D 299768 CDS YP_140811.1 55822370 3166869 complement(376405..376887) 1 NC_006449.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 376887 luxS 3166869 luxS Streptococcus thermophilus CNRZ1066 S-ribosylhomocysteinase YP_140811.1 376405 R 299768 CDS YP_140812.1 55822371 3167102 377034..377270 1 NC_006449.1 truncated; type I restriction modification system specificity subunit, truncated 377270 3167102 str0395 Streptococcus thermophilus CNRZ1066 type I restriction modification system specificity subunit, truncated YP_140812.1 377034 D 299768 CDS YP_140813.1 55822372 3166122 377421..378101 1 NC_006449.1 IS1216 transposase 378101 tnp1216 3166122 tnp1216 Streptococcus thermophilus CNRZ1066 IS1216 transposase YP_140813.1 377421 D 299768 CDS YP_140814.1 55822373 3166050 378515..380122 1 NC_006449.1 hypothetical protein 380122 3166050 str0397 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140814.1 378515 D 299768 CDS YP_140815.1 55822374 3167195 complement(380451..380990) 1 NC_006449.1 truncated; hypothetical protein 380990 3167195 str0398 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140815.1 380451 R 299768 CDS YP_140816.1 55822375 3167223 381548..382294 1 NC_006449.1 transcriptional repressor 382294 fruR 3167223 fruR Streptococcus thermophilus CNRZ1066 transcriptional repressor YP_140816.1 381548 D 299768 CDS YP_140817.1 55822376 3167085 382291..383202 1 NC_006449.1 fructose-1-phosphate kinase 383202 fruB 3167085 fruB Streptococcus thermophilus CNRZ1066 fructose-1-phosphate kinase YP_140817.1 382291 D 299768 CDS YP_140818.1 55822377 3166908 383232..383576 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 383576 3166908 str0401 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140818.1 383232 D 299768 CDS YP_140819.1 55822378 3166892 383595..383774 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 383774 3166892 str0402 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140819.1 383595 D 299768 CDS YP_140820.1 55822379 3166039 383767..383946 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 383946 3166039 str0403 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140820.1 383767 D 299768 CDS YP_140821.1 55822380 3167103 383943..384155 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 384155 3167103 str0404 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140821.1 383943 D 299768 CDS YP_140822.1 55822381 3166156 384152..384868 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 384868 3166156 str0405 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140822.1 384152 D 299768 CDS YP_140823.1 55822382 3166991 384861..385178 1 NC_006449.1 truncated; PTS system fructose-specific transporter subunit IIABC, truncated 385178 3166991 str0407 Streptococcus thermophilus CNRZ1066 PTS system fructose-specific transporter subunit IIABC, truncated YP_140823.1 384861 D 299768 CDS YP_140824.1 55822383 3167221 385328..386680 1 NC_006449.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 386680 gor 3167221 gor Streptococcus thermophilus CNRZ1066 glutathione reductase YP_140824.1 385328 D 299768 CDS YP_140825.1 55822384 3167111 complement(386782..388038) 1 NC_006449.1 folylpolyglutamate synthase / dihydrofolate synthase 388038 folC1 3167111 folC1 Streptococcus thermophilus CNRZ1066 folylpolyglutamate synthase / dihydrofolate synthase YP_140825.1 386782 R 299768 CDS YP_140826.1 55822385 3165736 complement(388084..388626) 1 NC_006449.1 hypothetical protein 388626 3165736 str0410 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140826.1 388084 R 299768 CDS YP_140827.1 55822386 3167082 388735..389880 1 NC_006449.1 class V aminotransferase 389880 nifS2 3167082 nifS2 Streptococcus thermophilus CNRZ1066 class V aminotransferase YP_140827.1 388735 D 299768 CDS YP_140828.1 55822387 3167140 389935..391158 1 NC_006449.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 391158 thiI 3167140 thiI Streptococcus thermophilus CNRZ1066 thiamine biosynthesis protein ThiI YP_140828.1 389935 D 299768 CDS YP_140829.1 55822388 3166145 391264..392775 1 NC_006449.1 glycosyltransferase teichoic acid biosynthesis protein 392775 3166145 str0413 Streptococcus thermophilus CNRZ1066 glycosyltransferase teichoic acid biosynthesis protein YP_140829.1 391264 D 299768 CDS YP_140830.1 55822389 3167180 392768..394087 1 NC_006449.1 hypothetical protein 394087 3167180 str0414 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140830.1 392768 D 299768 CDS YP_140831.1 55822390 3167242 394041..394457 1 NC_006449.1 truncated; hypothetical protein 394457 3167242 str0415 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140831.1 394041 D 299768 CDS YP_140832.1 55822391 3167542 394400..394627 1 NC_006449.1 truncated; hypothetical protein 394627 3167542 str0416 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140832.1 394400 D 299768 CDS YP_140833.2 161936378 3166642 394856..395170 1 NC_006449.1 50S ribosomal protein L21 395170 rplU 3166642 rplU Streptococcus thermophilus CNRZ1066 50S ribosomal protein L21 YP_140833.2 394856 D 299768 CDS YP_140834.1 55822393 3167539 395207..395497 1 NC_006449.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 395497 rpmA 3167539 rpmA Streptococcus thermophilus CNRZ1066 50S ribosomal protein L27 YP_140834.1 395207 D 299768 CDS YP_140835.1 55822394 3167076 395556..396083 1 NC_006449.1 truncated; acetyltransferase 396083 3167076 str0419 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_140835.1 395556 D 299768 CDS YP_140836.1 55822395 3166905 396025..396252 1 NC_006449.1 truncated; acetyltransferase 396252 3166905 str0420 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_140836.1 396025 D 299768 CDS YP_140837.1 55822396 3167184 396453..396827 1 NC_006449.1 hypothetical protein 396827 3167184 str0421 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140837.1 396453 D 299768 CDS YP_140838.1 55822397 3166888 396829..397041 1 NC_006449.1 truncated; hypothetical protein 397041 3166888 str0422 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140838.1 396829 D 299768 CDS YP_140839.1 55822398 3167041 397034..397672 1 NC_006449.1 truncated; hypothetical protein 397672 3167041 str0423 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140839.1 397034 D 299768 CDS YP_140840.1 55822399 3167243 397733..398500 1 NC_006449.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 398500 dapB 3167243 dapB Streptococcus thermophilus CNRZ1066 dihydrodipicolinate reductase YP_140840.1 397733 D 299768 CDS YP_140841.1 55822400 3166946 398497..399705 1 NC_006449.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 399705 papL 3166946 papL Streptococcus thermophilus CNRZ1066 tRNA CCA-pyrophosphorylase YP_140841.1 398497 D 299768 CDS YP_140842.1 55822401 3166830 399783..401663 1 NC_006449.1 ABC transporter ATP binding protein 401663 3166830 str0426 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140842.1 399783 D 299768 CDS YP_140843.1 55822402 3167231 complement(401745..402248) 1 NC_006449.1 hypothetical protein 402248 3167231 str0427 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140843.1 401745 R 299768 CDS YP_140844.1 55822403 3166784 complement(402325..403077) 1 NC_006449.1 MutT/nudix family protein 403077 3166784 str0428 Streptococcus thermophilus CNRZ1066 MutT/nudix family protein YP_140844.1 402325 R 299768 CDS YP_140845.1 55822404 3167148 complement(403141..404247) 1 NC_006449.1 transcriptional regulator 404247 nadR 3167148 nadR Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_140845.1 403141 R 299768 CDS YP_140846.1 55822405 3165688 404573..405943 1 NC_006449.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 405943 gdhA 3165688 gdhA Streptococcus thermophilus CNRZ1066 glutamate dehydrogenase YP_140846.1 404573 D 299768 CDS YP_140847.1 55822406 3167091 406202..406612 1 NC_006449.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 406612 defA 3167091 defA Streptococcus thermophilus CNRZ1066 peptide deformylase YP_140847.1 406202 D 299768 CDS YP_140848.1 55822407 3166605 406804..407247 1 NC_006449.1 MarR family transcriptional regulator 407247 3166605 str0432 Streptococcus thermophilus CNRZ1066 MarR family transcriptional regulator YP_140848.1 406804 D 299768 CDS YP_140849.1 55822408 3167212 407251..409065 1 NC_006449.1 ABC transporter ATP binding protein 409065 3167212 str0433 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140849.1 407251 D 299768 CDS YP_140850.1 55822409 3167125 409055..410833 1 NC_006449.1 ABC transporter ATP binding protein 410833 3167125 str0434 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140850.1 409055 D 299768 CDS YP_140851.1 55822410 3167233 410989..411237 1 NC_006449.1 hypothetical protein 411237 3167233 str0435 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140851.1 410989 D 299768 CDS YP_140852.1 55822411 3166319 complement(411511..411705) 1 NC_006449.1 hypothetical protein 411705 3166319 str0436 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140852.1 411511 R 299768 CDS YP_140853.1 55822412 3167049 411733..412449 1 NC_006449.1 truncated; sensor histidine kinase, uncoupled, truncated 412449 3167049 str0437 Streptococcus thermophilus CNRZ1066 sensor histidine kinase, uncoupled, truncated YP_140853.1 411733 D 299768 CDS YP_140854.1 55822413 3167237 412781..413518 1 NC_006449.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 413518 pyrH 3167237 pyrH Streptococcus thermophilus CNRZ1066 uridylate kinase YP_140854.1 412781 D 299768 CDS YP_140855.1 55822414 3167219 413533..414090 1 NC_006449.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 414090 frr 3167219 frr Streptococcus thermophilus CNRZ1066 ribosome recycling factor YP_140855.1 413533 D 299768 CDS YP_140856.1 55822415 3166327 414139..415038 1 NC_006449.1 hypothetical protein 415038 3166327 str0440 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140856.1 414139 D 299768 CDS YP_140857.1 55822416 3166973 415047..415262 1 NC_006449.1 hypothetical protein 415262 3166973 str0441 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140857.1 415047 D 299768 CDS YP_140858.1 55822417 3165687 416571..416960 1 NC_006449.1 glucan binding protein 416960 3165687 str0443 Streptococcus thermophilus CNRZ1066 glucan binding protein YP_140858.1 416571 D 299768 CDS YP_140859.1 55822418 3167362 complement(417074..417196) 1 NC_006449.1 truncated; truncated IS1193 transposase 417196 3167362 str0444 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_140859.1 417074 R 299768 CDS YP_140860.1 55822419 3167192 complement(417328..418281) 1 NC_006449.1 truncated; truncated IS1193 transposase 418281 3167192 str0445 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_140860.1 417328 R 299768 CDS YP_140861.1 55822420 3167414 418637..419152 1 NC_006449.1 truncated; surface immunogenic protein, truncated 419152 3167414 str0446 Streptococcus thermophilus CNRZ1066 surface immunogenic protein, truncated YP_140861.1 418637 D 299768 CDS YP_140862.1 55822421 3167033 419231..420292 1 NC_006449.1 phosphate starvation-induced protein 420292 phoH 3167033 phoH Streptococcus thermophilus CNRZ1066 phosphate starvation-induced protein YP_140862.1 419231 D 299768 CDS YP_140863.1 55822422 3165830 421500..421913 1 NC_006449.1 hypothetical protein 421913 3165830 str0448 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140863.1 421500 D 299768 CDS YP_140864.1 55822423 3165668 422384..422590 1 NC_006449.1 hypothetical protein 422590 3165668 str0449 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140864.1 422384 D 299768 CDS YP_140865.1 55822424 3167208 422587..422994 1 NC_006449.1 hypothetical protein 422994 3167208 str0450 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140865.1 422587 D 299768 CDS YP_140866.1 55822425 3167397 423188..425191 1 NC_006449.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 425191 metG 3167397 metG Streptococcus thermophilus CNRZ1066 methionyl-tRNA synthetase YP_140866.1 423188 D 299768 CDS YP_140867.1 55822426 3165950 complement(425469..426371) 1 NC_006449.1 LysR family transcriptional regulator 426371 3165950 str0452 Streptococcus thermophilus CNRZ1066 LysR family transcriptional regulator YP_140867.1 425469 R 299768 CDS YP_140868.1 55822427 3165852 427579..428622 1 NC_006449.1 competence protein, transcription factor 428622 coiA 3165852 coiA Streptococcus thermophilus CNRZ1066 competence protein, transcription factor YP_140868.1 427579 D 299768 CDS YP_140869.1 55822428 3167179 428633..430438 1 NC_006449.1 oligopeptidase 430438 pepB 3167179 pepB Streptococcus thermophilus CNRZ1066 oligopeptidase YP_140869.1 428633 D 299768 CDS YP_140870.1 55822429 3165758 430622..431329 1 NC_006449.1 methyltransferase 431329 3165758 str0455 Streptococcus thermophilus CNRZ1066 methyltransferase YP_140870.1 430622 D 299768 CDS YP_140871.1 55822430 3166053 431391..432506 1 NC_006449.1 protease maturation protein precursor 432506 prtM 3166053 prtM Streptococcus thermophilus CNRZ1066 protease maturation protein precursor YP_140871.1 431391 D 299768 CDS YP_140872.1 55822431 3167295 432848..435466 1 NC_006449.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 435466 alaS 3167295 alaS Streptococcus thermophilus CNRZ1066 alanyl-tRNA synthetase YP_140872.1 432848 D 299768 CDS YP_140873.1 55822432 3167224 435628..435849 1 NC_006449.1 truncated; cell wall protein precursor, choline binding protein, truncated 435849 3167224 str0458 Streptococcus thermophilus CNRZ1066 cell wall protein precursor, choline binding protein, truncated YP_140873.1 435628 D 299768 CDS YP_140874.1 55822433 3166457 435994..436503 1 NC_006449.1 truncated; cell wall protein precursor, choline binding protein, truncated 436503 3166457 str0459 Streptococcus thermophilus CNRZ1066 cell wall protein precursor, choline binding protein, truncated YP_140874.1 435994 D 299768 CDS YP_140875.1 55822434 3165821 436630..436893 1 NC_006449.1 truncated; cell wall protein precursor, choline binding protein, truncated 436893 3165821 str0460 Streptococcus thermophilus CNRZ1066 cell wall protein precursor, choline binding protein, truncated YP_140875.1 436630 D 299768 CDS YP_140876.1 55822435 3166611 437653..438162 1 NC_006449.1 truncated; cell wall protein precursor, choline binding protein, truncated 438162 3166611 str0461 Streptococcus thermophilus CNRZ1066 cell wall protein precursor, choline binding protein, truncated YP_140876.1 437653 D 299768 CDS YP_140877.1 55822436 3166695 438295..439083 1 NC_006449.1 hypothetical protein 439083 3166695 str0462 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140877.1 438295 D 299768 CDS YP_140878.1 55822437 3167178 439093..440274 1 NC_006449.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; transaminase 440274 aspC3 3167178 aspC3 Streptococcus thermophilus CNRZ1066 transaminase YP_140878.1 439093 D 299768 CDS YP_140879.1 55822438 3167144 440403..441425 1 NC_006449.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 441425 argC 3167144 argC Streptococcus thermophilus CNRZ1066 N-acetyl-gamma-glutamyl-phosphate reductase YP_140879.1 440403 D 299768 CDS YP_140880.1 55822439 3167142 441454..442647 1 NC_006449.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 442647 argJ 3167142 argJ Streptococcus thermophilus CNRZ1066 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_140880.1 441454 D 299768 CDS YP_140881.1 55822440 3167230 442674..443411 1 NC_006449.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 443411 argB 3167230 argB Streptococcus thermophilus CNRZ1066 acetylglutamate kinase YP_140881.1 442674 D 299768 CDS YP_140882.1 55822441 3167136 443415..444545 1 NC_006449.1 acetylornithine aminotransferase 444545 argD 3167136 argD Streptococcus thermophilus CNRZ1066 acetylornithine aminotransferase YP_140882.1 443415 D 299768 CDS YP_140883.1 55822442 3167276 complement(444586..445362) 1 NC_006449.1 hypothetical protein 445362 3167276 str0468 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140883.1 444586 R 299768 CDS YP_140884.1 55822443 3167205 445637..446923 1 NC_006449.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 446923 hom 3167205 hom Streptococcus thermophilus CNRZ1066 homoserine dehydrogenase YP_140884.1 445637 D 299768 CDS YP_140885.1 55822444 3167395 447007..447867 1 NC_006449.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 447867 thrB 3167395 thrB Streptococcus thermophilus CNRZ1066 homoserine kinase YP_140885.1 447007 D 299768 CDS YP_140886.1 55822445 3167364 447815..448744 1 NC_006449.1 hypothetical protein 448744 3167364 str0471 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140886.1 447815 D 299768 CDS YP_140887.1 55822446 3166815 448926..449474 1 NC_006449.1 hypothetical protein 449474 3166815 str0472 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140887.1 448926 D 299768 CDS YP_140888.1 55822447 3167074 449609..449812 1 NC_006449.1 hypothetical protein 449812 3167074 str0473 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140888.1 449609 D 299768 CDS YP_140889.1 55822448 3167181 450283..450846 1 NC_006449.1 hypothetical protein 450846 3167181 str0474 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140889.1 450283 D 299768 CDS YP_140890.1 55822449 3166708 450909..451196 1 NC_006449.1 acetyltransferase 451196 3166708 str0476 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_140890.1 450909 D 299768 CDS YP_140891.2 161936377 3166638 451427..454078 1 NC_006449.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 454078 valS 3166638 valS Streptococcus thermophilus CNRZ1066 valyl-tRNA synthetase YP_140891.2 451427 D 299768 CDS YP_140892.1 55822451 3167218 454255..454452 1 NC_006449.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 454452 atpE 3167218 atpE Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit C YP_140892.1 454255 D 299768 CDS YP_140893.1 55822452 3166538 454487..455194 1 NC_006449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 455194 atpB 3166538 atpB Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit A YP_140893.1 454487 D 299768 CDS YP_140894.1 55822453 3167264 455215..455712 1 NC_006449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 455712 atpF 3167264 atpF Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit B YP_140894.1 455215 D 299768 CDS YP_140895.1 55822454 3167263 455712..456248 1 NC_006449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 456248 atpH 3167263 atpH Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit delta YP_140895.1 455712 D 299768 CDS YP_140896.1 55822455 3167149 456264..457769 1 NC_006449.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 457769 atpA 3167149 atpA Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit alpha YP_140896.1 456264 D 299768 CDS YP_140897.1 55822456 3166679 457788..458666 1 NC_006449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 458666 atpG 3166679 atpG Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit gamma YP_140897.1 457788 D 299768 CDS YP_140898.1 55822457 3166385 458743..460149 1 NC_006449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 460149 atpD 3166385 atpD Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit beta YP_140898.1 458743 D 299768 CDS YP_140899.1 55822458 3167246 460162..460608 1 NC_006449.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 460608 atpC 3167246 atpC Streptococcus thermophilus CNRZ1066 ATP synthase F0F1 subunit epsilon YP_140899.1 460162 D 299768 CDS YP_140900.1 55822459 3167258 460845..462140 1 NC_006449.1 cell division protein 462140 ftsW 3167258 ftsW Streptococcus thermophilus CNRZ1066 cell division protein YP_140900.1 460845 D 299768 CDS YP_140901.1 55822460 3166113 462378..463574 1 NC_006449.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 463574 tuf 3166113 tuf Streptococcus thermophilus CNRZ1066 elongation factor Tu YP_140901.1 462378 D 299768 CDS YP_140902.1 55822461 3165874 463823..464581 1 NC_006449.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 464581 tpiA 3165874 tpiA Streptococcus thermophilus CNRZ1066 triosephosphate isomerase YP_140902.1 463823 D 299768 CDS YP_140903.1 55822462 3167241 464819..465448 1 NC_006449.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 465448 tmk 3167241 tmk Streptococcus thermophilus CNRZ1066 thymidylate kinase YP_140903.1 464819 D 299768 CDS YP_140904.1 55822463 3167287 465457..466332 1 NC_006449.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 466332 dnaH 3167287 dnaH Streptococcus thermophilus CNRZ1066 DNA polymerase III subunit delta' YP_140904.1 465457 D 299768 CDS YP_140905.1 55822464 3167249 466329..467135 1 NC_006449.1 signal-petidase-like protein 467135 sip 3167249 sip Streptococcus thermophilus CNRZ1066 signal-petidase-like protein YP_140905.1 466329 D 299768 CDS YP_140906.1 55822465 3166372 467122..467442 1 NC_006449.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 467442 3166372 str0492 Streptococcus thermophilus CNRZ1066 DNA replication intiation control protein YabA YP_140906.1 467122 D 299768 CDS YP_140907.1 55822466 3167297 467445..468311 1 NC_006449.1 tetrapyrrole methylase family protein 468311 3167297 str0493 Streptococcus thermophilus CNRZ1066 tetrapyrrole methylase family protein YP_140907.1 467445 D 299768 CDS YP_140908.1 55822467 3167204 468400..469683 1 NC_006449.1 ammonium transporter 469683 amtB 3167204 amtB Streptococcus thermophilus CNRZ1066 ammonium transporter YP_140908.1 468400 D 299768 CDS YP_140909.1 55822468 3166877 469628..470035 1 NC_006449.1 nitrogen regulatory protein P-II 470035 gnlB 3166877 gnlB Streptococcus thermophilus CNRZ1066 nitrogen regulatory protein P-II YP_140909.1 469628 D 299768 CDS YP_140910.1 55822469 3166281 470133..470789 1 NC_006449.1 peptidoglycan hydrolase 470789 mur1 3166281 mur1 Streptococcus thermophilus CNRZ1066 peptidoglycan hydrolase YP_140910.1 470133 D 299768 CDS YP_140911.1 55822470 3166555 470776..471633 1 NC_006449.1 hypothetical protein 471633 3166555 str0497 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140911.1 470776 D 299768 CDS YP_140912.1 55822471 3166743 472162..472404 1 NC_006449.1 truncated; Na/Pi cotransporter II-related protein, truncated 472404 3166743 str0498 Streptococcus thermophilus CNRZ1066 Na/Pi cotransporter II-related protein, truncated YP_140912.1 472162 D 299768 CDS YP_140913.1 55822472 3166612 472364..472936 1 NC_006449.1 truncated; Na/Pi cotransporter II-related protein, truncated 472936 3166612 str0499 Streptococcus thermophilus CNRZ1066 Na/Pi cotransporter II-related protein, truncated YP_140913.1 472364 D 299768 CDS YP_140914.1 55822473 3167254 473003..474169 1 NC_006449.1 N-acetylglucosamine-6-phosphate deacetylase 474169 nagA 3167254 nagA Streptococcus thermophilus CNRZ1066 N-acetylglucosamine-6-phosphate deacetylase YP_140914.1 473003 D 299768 CDS YP_140915.1 55822474 3167262 474470..474772 1 NC_006449.1 truncated; hypothetical protein 474772 3167262 str0503 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140915.1 474470 D 299768 CDS YP_140916.1 55822475 3166732 474756..475124 1 NC_006449.1 truncated; hypothetical protein 475124 3166732 str0504 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140916.1 474756 D 299768 CDS YP_140917.1 55822477 3167427 complement(475654..475830) 1 NC_006449.1 hypothetical protein 475830 3167427 str0506 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140917.1 475654 R 299768 CDS YP_140918.1 55822476 3167152 475799..476716 1 NC_006449.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 476716 glyQ 3167152 glyQ Streptococcus thermophilus CNRZ1066 glycyl-tRNA synthetase subunit alpha YP_140918.1 475799 D 299768 CDS YP_140919.2 161936376 3166325 477000..479036 1 NC_006449.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 479036 glyS 3166325 glyS Streptococcus thermophilus CNRZ1066 glycyl-tRNA synthetase subunit beta YP_140919.2 477000 D 299768 CDS YP_140920.1 55822479 3167390 479049..479306 1 NC_006449.1 hypothetical protein 479306 3167390 str0508 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140920.1 479049 D 299768 CDS YP_140921.1 55822480 3167227 479468..480868 1 NC_006449.1 amino acid permease 480868 3167227 str0509 Streptococcus thermophilus CNRZ1066 amino acid permease YP_140921.1 479468 D 299768 CDS YP_140922.1 55822481 3165744 complement(480939..481574) 1 NC_006449.1 hypothetical protein 481574 3165744 str0510 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140922.1 480939 R 299768 CDS YP_140923.1 55822482 3165692 481876..482052 1 NC_006449.1 truncated; PTS system beta-glucoside-specific transporter subunit IIABC, truncated 482052 3165692 str0511 Streptococcus thermophilus CNRZ1066 PTS system beta-glucoside-specific transporter subunit IIABC, truncated YP_140923.1 481876 D 299768 CDS YP_140924.1 55822483 3167382 482065..482499 1 NC_006449.1 truncated; PTS system beta-glucoside-specific transporter subunit IIABC, truncated 482499 3167382 str0512 Streptococcus thermophilus CNRZ1066 PTS system beta-glucoside-specific transporter subunit IIABC, truncated YP_140924.1 482065 D 299768 CDS YP_140925.1 55822484 3167259 482677..483261 1 NC_006449.1 truncated; PTS system beta-glucoside-specific transporter subunit IIABC, truncated 483261 3167259 str0513 Streptococcus thermophilus CNRZ1066 PTS system beta-glucoside-specific transporter subunit IIABC, truncated YP_140925.1 482677 D 299768 CDS YP_140926.1 55822485 3167168 483239..483697 1 NC_006449.1 truncated; PTS system beta-glucoside-specific transporter subunit IIABC, truncated 483697 3167168 str0514 Streptococcus thermophilus CNRZ1066 PTS system beta-glucoside-specific transporter subunit IIABC, truncated YP_140926.1 483239 D 299768 CDS YP_140927.1 55822486 3167260 complement(483819..484577) 1 NC_006449.1 peptidyl-prolyl cis-trans isomerase 484577 ppiA 3167260 ppiA Streptococcus thermophilus CNRZ1066 peptidyl-prolyl cis-trans isomerase YP_140927.1 483819 R 299768 CDS YP_140928.1 55822487 3167358 484937..485200 1 NC_006449.1 hypothetical protein 485200 3167358 str0516 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140928.1 484937 D 299768 CDS YP_140929.1 55822488 3167170 485264..485671 1 NC_006449.1 hypothetical protein 485671 3167170 str0517 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140929.1 485264 D 299768 CDS YP_140930.1 55822489 3166856 485668..486144 1 NC_006449.1 hypothetical protein 486144 3166856 str0518 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140930.1 485668 D 299768 CDS YP_140931.1 55822490 3167247 486290..486514 1 NC_006449.1 hypothetical protein 486514 3167247 str0519 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140931.1 486290 D 299768 CDS YP_140932.1 55822491 3167232 486621..487535 1 NC_006449.1 LysR family transcriptional regulator 487535 3167232 str0520 Streptococcus thermophilus CNRZ1066 LysR family transcriptional regulator YP_140932.1 486621 D 299768 CDS YP_140933.1 55822492 3167234 487544..488005 1 NC_006449.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 488005 lspA 3167234 lspA Streptococcus thermophilus CNRZ1066 lipoprotein signal peptidase YP_140933.1 487544 D 299768 CDS YP_140934.1 55822493 3167206 487989..488867 1 NC_006449.1 ribosomal large subunit pseudouridine synthase D 488867 rluD 3167206 rluD Streptococcus thermophilus CNRZ1066 ribosomal large subunit pseudouridine synthase D YP_140934.1 487989 D 299768 CDS YP_140935.1 55822494 3167270 489108..489629 1 NC_006449.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 489629 pyrR 3167270 pyrR Streptococcus thermophilus CNRZ1066 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_140935.1 489108 D 299768 CDS YP_140936.1 55822495 3166198 489943..491253 1 NC_006449.1 uracil permease 491253 pyrP 3166198 pyrP Streptococcus thermophilus CNRZ1066 uracil permease YP_140936.1 489943 D 299768 CDS YP_140937.1 55822496 3166175 491278..492204 1 NC_006449.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 492204 pyrB 3166175 pyrB Streptococcus thermophilus CNRZ1066 aspartate carbamoyltransferase YP_140937.1 491278 D 299768 CDS YP_140938.1 55822497 3166951 492357..493445 1 NC_006449.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 493445 carA 3166951 carA Streptococcus thermophilus CNRZ1066 carbamoyl phosphate synthase small subunit YP_140938.1 492357 D 299768 CDS YP_140939.1 55822498 3167401 493790..496969 1 NC_006449.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 496969 carB 3167401 carB Streptococcus thermophilus CNRZ1066 carbamoyl phosphate synthase large subunit YP_140939.1 493790 D 299768 CDS YP_140940.1 55822499 3167113 497346..498104 1 NC_006449.1 hypothetical protein 498104 3167113 str0528 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140940.1 497346 D 299768 CDS YP_140941.1 55822500 3167177 498412..498723 1 NC_006449.1 hypothetical protein 498723 3167177 str0529 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140941.1 498412 D 299768 CDS YP_140942.1 55822501 3167215 498963..499208 1 NC_006449.1 hypothetical protein 499208 3167215 str0530 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140942.1 498963 D 299768 CDS YP_140943.1 55822502 3166879 499201..499524 1 NC_006449.1 truncated; ABC transporter permease, truncated 499524 3166879 str0531 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_140943.1 499201 D 299768 CDS YP_140944.1 55822503 3167167 499525..499767 1 NC_006449.1 truncated; ABC transporter permease, truncated 499767 3167167 str0533 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_140944.1 499525 D 299768 CDS YP_140945.1 55822504 3167196 499784..500032 1 NC_006449.1 truncated; ABC transporter permease, truncated 500032 3167196 str0534 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_140945.1 499784 D 299768 CDS YP_140946.1 55822505 3167256 500041..500244 1 NC_006449.1 truncated; ABC transporter permease, truncated 500244 3167256 str0535 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_140946.1 500041 D 299768 CDS YP_140947.2 161936375 3166728 500534..501037 1 NC_006449.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 501037 rplJ 3166728 rplJ Streptococcus thermophilus CNRZ1066 50S ribosomal protein L10 YP_140947.2 500534 D 299768 CDS YP_140948.2 161936374 3167273 501112..501480 1 NC_006449.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 501480 rplL 3167273 rplL Streptococcus thermophilus CNRZ1066 50S ribosomal protein L7/L12 YP_140948.2 501112 D 299768 CDS YP_140949.1 55822508 3167374 502734..504470 1 NC_006449.1 ABC transporter ATP binding/permease 504470 3167374 str0538 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding/permease YP_140949.1 502734 D 299768 CDS YP_140950.1 55822509 3166346 504483..506270 1 NC_006449.1 ABC transporter ATP binding/permease 506270 3166346 str0539 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding/permease YP_140950.1 504483 D 299768 CDS YP_140951.1 55822510 3166064 complement(506368..507411) 1 NC_006449.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 507411 queA 3166064 queA Streptococcus thermophilus CNRZ1066 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_140951.1 506368 R 299768 CDS YP_140952.1 55822511 3167487 507486..508262 1 NC_006449.1 glucosamine-6-phosphate isomerase 508262 nagB 3167487 nagB Streptococcus thermophilus CNRZ1066 glucosamine-6-phosphate isomerase YP_140952.1 507486 D 299768 CDS YP_140953.1 55822512 3167384 complement(508428..509057) 1 NC_006449.1 truncated; sensor histidine kinase, truncated 509057 3167384 str0542 Streptococcus thermophilus CNRZ1066 sensor histidine kinase, truncated YP_140953.1 508428 R 299768 CDS YP_140954.1 55822513 3166065 complement(509723..510448) 1 NC_006449.1 response regulator 510448 rr02 3166065 rr02 Streptococcus thermophilus CNRZ1066 response regulator YP_140954.1 509723 R 299768 CDS YP_140955.1 55822514 3166935 510770..511240 1 NC_006449.1 hypothetical protein 511240 3166935 str0544 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140955.1 510770 D 299768 CDS YP_140956.1 55822515 3167265 511230..511904 1 NC_006449.1 truncated; molybdopterin biosynthesis protein 511904 3167265 str0545 Streptococcus thermophilus CNRZ1066 molybdopterin biosynthesis protein YP_140956.1 511230 D 299768 CDS YP_140957.1 55822516 3166948 511865..512812 1 NC_006449.1 ABC transporter ATP binding protein 512812 3166948 str0546 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_140957.1 511865 D 299768 CDS YP_140958.1 55822517 3166063 512814..513536 1 NC_006449.1 ABC transporter permease 513536 3166063 str0547 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_140958.1 512814 D 299768 CDS YP_140959.1 55822518 3166342 513725..514708 1 NC_006449.1 hypothetical protein 514708 3166342 str0548 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140959.1 513725 D 299768 CDS YP_140960.1 55822519 3167238 514866..515084 1 NC_006449.1 transcriptional repressor 515084 3167238 str0549 Streptococcus thermophilus CNRZ1066 transcriptional repressor YP_140960.1 514866 D 299768 CDS YP_140961.1 55822520 3166066 515098..515595 1 NC_006449.1 hypothetical protein 515595 3166066 str0550 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140961.1 515098 D 299768 CDS YP_140962.1 55822521 3167109 515674..516444 1 NC_006449.1 phosphorylase Pnp/Udp family protein 516444 3167109 str0551 Streptococcus thermophilus CNRZ1066 phosphorylase Pnp/Udp family protein YP_140962.1 515674 D 299768 CDS YP_140963.1 55822522 3167132 516535..517218 1 NC_006449.1 hypothetical protein 517218 3167132 str0552 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140963.1 516535 D 299768 CDS YP_140964.1 55822523 3166254 517298..518017 1 NC_006449.1 ribosomal small subunit pseudouridine synthase A 518017 rsuA1 3166254 rsuA1 Streptococcus thermophilus CNRZ1066 ribosomal small subunit pseudouridine synthase A YP_140964.1 517298 D 299768 CDS YP_140965.1 55822524 3167404 518253..519398 1 NC_006449.1 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 519398 hipO1 3167404 hipO1 Streptococcus thermophilus CNRZ1066 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_140965.1 518253 D 299768 CDS YP_140966.1 55822525 3166253 519831..519968 1 NC_006449.1 truncated; alanine dehydrogenase 519968 3166253 str0555 Streptococcus thermophilus CNRZ1066 alanine dehydrogenase YP_140966.1 519831 D 299768 CDS YP_140967.1 55822526 3167146 519943..520230 1 NC_006449.1 truncated; alanine dehydrogenase 520230 3167146 str0556 Streptococcus thermophilus CNRZ1066 alanine dehydrogenase YP_140967.1 519943 D 299768 CDS YP_140968.1 55822527 3166255 520939..522255 1 NC_006449.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 522255 3166255 str0557 Streptococcus thermophilus CNRZ1066 pyridine nucleotide-disulfide oxidoreductase YP_140968.1 520939 D 299768 CDS YP_140969.1 55822528 3166984 complement(522474..523037) 1 NC_006449.1 hypothetical protein 523037 3166984 str0558 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140969.1 522474 R 299768 CDS YP_140970.1 55822529 3167392 523300..524178 1 NC_006449.1 mevalonate kinase 524178 mvaK1 3167392 mvaK1 Streptococcus thermophilus CNRZ1066 mevalonate kinase YP_140970.1 523300 D 299768 CDS YP_140971.1 55822530 3166674 524160..525104 1 NC_006449.1 mevalonate pyrophosphate decarboxylase 525104 mvaD 3166674 mvaD Streptococcus thermophilus CNRZ1066 mevalonate pyrophosphate decarboxylase YP_140971.1 524160 D 299768 CDS YP_140972.1 55822531 3167035 525097..526092 1 NC_006449.1 phosphomevalonate kinase 526092 mvaK2 3167035 mvaK2 Streptococcus thermophilus CNRZ1066 phosphomevalonate kinase YP_140972.1 525097 D 299768 CDS YP_140973.1 55822532 3166577 526142..527149 1 NC_006449.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 527149 idi 3166577 idi Streptococcus thermophilus CNRZ1066 isopentenyl pyrophosphate isomerase YP_140973.1 526142 D 299768 CDS YP_140974.1 55822533 3166166 527699..529081 1 NC_006449.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 529081 glmU 3166166 glmU Streptococcus thermophilus CNRZ1066 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_140974.1 527699 D 299768 CDS YP_140975.1 55822534 3166315 529157..529705 1 NC_006449.1 hypothetical protein 529705 3166315 str0564 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140975.1 529157 D 299768 CDS YP_140976.1 55822535 3167173 529709..529969 1 NC_006449.1 hypothetical protein 529969 3167173 str0565 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140976.1 529709 D 299768 CDS YP_140977.1 55822536 3167240 530037..530729 1 NC_006449.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 530729 pfs 3167240 pfs Streptococcus thermophilus CNRZ1066 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_140977.1 530037 D 299768 CDS YP_140978.1 55822537 3167388 531648..532118 1 NC_006449.1 truncated; hypothetical protein 532118 3167388 str0567 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140978.1 531648 D 299768 CDS YP_140979.1 55822538 3167368 532249..532515 1 NC_006449.1 hypothetical protein 532515 3167368 str0568 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140979.1 532249 D 299768 CDS YP_140980.1 55822539 3166842 532665..533669 1 NC_006449.1 glycosyl transferase family protein 533669 3166842 str0569 Streptococcus thermophilus CNRZ1066 glycosyl transferase family protein YP_140980.1 532665 D 299768 CDS YP_140981.1 55822540 3165904 533670..534992 1 NC_006449.1 glycosyl transferase family protein 534992 3165904 str0570 Streptococcus thermophilus CNRZ1066 glycosyl transferase family protein YP_140981.1 533670 D 299768 CDS YP_140982.1 55822541 3165643 535264..535551 1 NC_006449.1 hypothetical protein 535551 3165643 str0571 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140982.1 535264 D 299768 CDS YP_140983.1 55822542 3166329 535705..537651 1 NC_006449.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 537651 thrS 3166329 thrS Streptococcus thermophilus CNRZ1066 threonyl-tRNA synthetase YP_140983.1 535705 D 299768 CDS YP_140984.1 55822543 3165891 537701..538642 1 NC_006449.1 hydrolase 538642 3165891 str0573 Streptococcus thermophilus CNRZ1066 hydrolase YP_140984.1 537701 D 299768 CDS YP_140985.1 55822544 3166247 538662..539528 1 NC_006449.1 hypothetical protein 539528 3166247 str0574 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140985.1 538662 D 299768 CDS YP_140986.1 55822545 3166107 complement(540035..540712) 1 NC_006449.1 hemolysin III 540712 hlyIII 3166107 hlyIII Streptococcus thermophilus CNRZ1066 hemolysin III YP_140986.1 540035 R 299768 CDS YP_140987.1 55822546 3166663 complement(541330..542601) 1 NC_006449.1 3-hydroxy-3-methylglutaryl-CoA reductase 542601 mvaA 3166663 mvaA Streptococcus thermophilus CNRZ1066 3-hydroxy-3-methylglutaryl-CoA reductase YP_140987.1 541330 R 299768 CDS YP_140988.1 55822547 3166887 complement(542594..543793) 1 NC_006449.1 hydroxymethylglutaryl-CoA synthase 543793 mvaS 3166887 mvaS Streptococcus thermophilus CNRZ1066 hydroxymethylglutaryl-CoA synthase YP_140988.1 542594 R 299768 CDS YP_140989.1 55822548 3166858 544091..544951 1 NC_006449.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 544951 thyA 3166858 thyA Streptococcus thermophilus CNRZ1066 thymidylate synthase YP_140989.1 544091 D 299768 CDS YP_140990.1 55822549 3167117 545059..545562 1 NC_006449.1 dihydrofolate reductase 545562 folA 3167117 folA Streptococcus thermophilus CNRZ1066 dihydrofolate reductase YP_140990.1 545059 D 299768 CDS YP_140991.1 55822550 3166913 545567..545737 1 NC_006449.1 hypothetical protein 545737 3166913 str0580 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140991.1 545567 D 299768 CDS YP_140992.1 55822551 3166619 545755..546981 1 NC_006449.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 546981 clpX 3166619 clpX Streptococcus thermophilus CNRZ1066 ATP-dependent protease ATP-binding subunit ClpX YP_140992.1 545755 D 299768 CDS YP_140993.1 55822552 3166633 546991..547590 1 NC_006449.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 547590 engB 3166633 engB Streptococcus thermophilus CNRZ1066 ribosome biogenesis GTP-binding protein YsxC YP_140993.1 546991 D 299768 CDS YP_140994.1 55822553 3165671 547645..549096 1 NC_006449.1 amino acid permease 549096 3165671 str0583 Streptococcus thermophilus CNRZ1066 amino acid permease YP_140994.1 547645 D 299768 CDS YP_140995.1 55822554 3166912 549090..550058 1 NC_006449.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 550058 mmuM 3166912 mmuM Streptococcus thermophilus CNRZ1066 homocysteine methyltransferase YP_140995.1 549090 D 299768 CDS YP_140996.1 55822555 3166814 550171..550425 1 NC_006449.1 hypothetical protein 550425 3166814 str0585 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140996.1 550171 D 299768 CDS YP_140997.1 55822556 3165890 550497..550856 1 NC_006449.1 hypothetical protein 550856 3165890 str0586 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_140997.1 550497 D 299768 CDS YP_140998.1 55822557 3165696 complement(550970..551611) 1 NC_006449.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 551611 3165696 str0587 Streptococcus thermophilus CNRZ1066 glycerol-3-phosphate acyltransferase PlsY YP_140998.1 550970 R 299768 CDS YP_140999.1 55822558 3166536 551749..553698 1 NC_006449.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 553698 parE 3166536 parE Streptococcus thermophilus CNRZ1066 DNA topoisomerase IV subunit B YP_140999.1 551749 D 299768 CDS YP_141000.1 55822559 3166786 554272..556791 1 NC_006449.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 556791 parC 3166786 parC Streptococcus thermophilus CNRZ1066 DNA topoisomerase IV subunit A YP_141000.1 554272 D 299768 CDS YP_141001.1 55822560 3166413 556955..557977 1 NC_006449.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 557977 bcaT 3166413 bcaT Streptococcus thermophilus CNRZ1066 branched-chain amino acid aminotransferase YP_141001.1 556955 D 299768 CDS YP_141002.1 55822561 3166250 558096..558326 1 NC_006449.1 hypothetical protein 558326 3166250 str0591 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141002.1 558096 D 299768 CDS YP_141003.2 161936373 3166371 558728..559930 1 NC_006449.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 559930 rpsA 3166371 rpsA Streptococcus thermophilus CNRZ1066 30S ribosomal protein S1 YP_141003.2 558728 D 299768 CDS YP_141004.1 55822563 3166709 560758..560994 1 NC_006449.1 hypothetical protein 560994 3166709 str0593 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141004.1 560758 D 299768 CDS YP_141005.1 55822564 3166188 561152..561379 1 NC_006449.1 hypothetical protein 561379 3166188 str0594 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141005.1 561152 D 299768 CDS YP_141006.1 55822565 3166456 561592..562134 1 NC_006449.1 hypothetical protein 562134 3166456 str0595 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141006.1 561592 D 299768 CDS YP_141007.1 55822566 3166820 562112..563347 1 NC_006449.1 peptidoglycan branched peptide synthesis protein, alanine adding enzyme 563347 murN 3166820 murN Streptococcus thermophilus CNRZ1066 peptidoglycan branched peptide synthesis protein, alanine adding enzyme YP_141007.1 562112 D 299768 CDS YP_141008.1 55822567 3165659 563622..563780 1 NC_006449.1 truncated; oxidoreductase, truncated 563780 3165659 str0597 Streptococcus thermophilus CNRZ1066 oxidoreductase, truncated YP_141008.1 563622 D 299768 CDS YP_141009.1 55822568 3166846 563796..563981 1 NC_006449.1 truncated; oxidoreductase, truncated 563981 3166846 str0598 Streptococcus thermophilus CNRZ1066 oxidoreductase, truncated YP_141009.1 563796 D 299768 CDS YP_141010.1 55822569 3166314 564093..564407 1 NC_006449.1 truncated; oxidoreductase, truncated 564407 3166314 str0599 Streptococcus thermophilus CNRZ1066 oxidoreductase, truncated YP_141010.1 564093 D 299768 CDS YP_141011.1 55822570 3166763 complement(564448..564750) 1 NC_006449.1 hypothetical protein 564750 3166763 str0600 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141011.1 564448 R 299768 CDS YP_141012.1 55822571 3166819 complement(564760..565218) 1 NC_006449.1 MutT/nudix family protein 565218 3166819 str0601 Streptococcus thermophilus CNRZ1066 MutT/nudix family protein YP_141012.1 564760 R 299768 CDS YP_141013.1 55822572 3166635 complement(565361..567619) 1 NC_006449.1 ATP-dependent Clp protease 567619 clpE 3166635 clpE Streptococcus thermophilus CNRZ1066 ATP-dependent Clp protease YP_141013.1 565361 R 299768 CDS YP_141014.1 55822573 3166876 567797..568840 1 NC_006449.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 568840 argF 3166876 argF Streptococcus thermophilus CNRZ1066 ornithine carbamoyltransferase YP_141014.1 567797 D 299768 CDS YP_141015.1 55822574 3166106 568909..569139 1 NC_006449.1 hypothetical protein 569139 3166106 str0604 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141015.1 568909 D 299768 CDS YP_141016.1 55822575 3166843 569406..570089 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 570089 3166843 str0605 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141016.1 569406 D 299768 CDS YP_141017.1 55822576 3166874 570089..570823 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 570823 3166874 str0606 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_141017.1 570089 D 299768 CDS YP_141018.1 55822577 3166920 570997..571473 1 NC_006449.1 ferrous ion transport protein A 571473 feoA 3166920 feoA Streptococcus thermophilus CNRZ1066 ferrous ion transport protein A YP_141018.1 570997 D 299768 CDS YP_141019.1 55822578 3166056 571470..573608 1 NC_006449.1 ferrous ion transport protein B 573608 feoB 3166056 feoB Streptococcus thermophilus CNRZ1066 ferrous ion transport protein B YP_141019.1 571470 D 299768 CDS YP_141020.1 55822579 3166279 573995..574219 1 NC_006449.1 hypothetical protein 574219 3166279 str0609 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141020.1 573995 D 299768 CDS YP_141021.1 55822580 3166544 574467..574658 1 NC_006449.1 hypothetical protein 574658 3166544 str0610 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141021.1 574467 D 299768 CDS YP_141022.1 55822581 3166337 574819..575685 1 NC_006449.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 575685 folD 3166337 folD Streptococcus thermophilus CNRZ1066 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_141022.1 574819 D 299768 CDS YP_141023.1 55822582 3166592 575689..576525 1 NC_006449.1 hypothetical protein 576525 3166592 str0612 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141023.1 575689 D 299768 CDS YP_141024.1 55822583 3166534 576647..578761 1 NC_006449.1 penicillin-binding protein 2B 578761 pbp2B 3166534 pbp2B Streptococcus thermophilus CNRZ1066 penicillin-binding protein 2B YP_141024.1 576647 D 299768 CDS YP_141025.1 55822584 3166423 578871..579467 1 NC_006449.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 579467 recR 3166423 recR Streptococcus thermophilus CNRZ1066 recombination protein RecR YP_141025.1 578871 D 299768 CDS YP_141026.1 55822585 3166583 579608..579979 1 NC_006449.1 truncated; BglG family transcriptional antiterminator, truncated 579979 3166583 str0615 Streptococcus thermophilus CNRZ1066 BglG family transcriptional antiterminator, truncated YP_141026.1 579608 D 299768 CDS YP_141027.1 55822586 3166406 580087..580404 1 NC_006449.1 truncated; BglG family transcriptional antiterminator, truncated 580404 3166406 str0616 Streptococcus thermophilus CNRZ1066 BglG family transcriptional antiterminator, truncated YP_141027.1 580087 D 299768 CDS YP_141028.1 55822587 3165896 580624..581121 1 NC_006449.1 metalloprotease 581121 3165896 str0617 Streptococcus thermophilus CNRZ1066 metalloprotease YP_141028.1 580624 D 299768 CDS YP_141029.1 55822588 3166357 581102..581506 1 NC_006449.1 diacylglycerol kinase 581506 dgk 3166357 dgk Streptococcus thermophilus CNRZ1066 diacylglycerol kinase YP_141029.1 581102 D 299768 CDS YP_141030.1 55822589 3166758 581525..582424 1 NC_006449.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 582424 era 3166758 era Streptococcus thermophilus CNRZ1066 GTP-binding protein Era YP_141030.1 581525 D 299768 CDS YP_141031.1 55822590 3166111 582471..583292 1 NC_006449.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 583292 mutM 3166111 mutM Streptococcus thermophilus CNRZ1066 formamidopyrimidine-DNA glycosylase YP_141031.1 582471 D 299768 CDS YP_141032.1 55822591 3166343 583268..583882 1 NC_006449.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 583882 coaE 3166343 coaE Streptococcus thermophilus CNRZ1066 dephospho-CoA kinase YP_141032.1 583268 D 299768 CDS YP_141033.1 55822592 3166270 583933..585156 1 NC_006449.1 multi-drug resistance efflux pump 585156 pmrA 3166270 pmrA Streptococcus thermophilus CNRZ1066 multi-drug resistance efflux pump YP_141033.1 583933 D 299768 CDS YP_141034.1 55822593 3166402 585146..585292 1 NC_006449.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 585292 rpmG 3166402 rpmG Streptococcus thermophilus CNRZ1066 50S ribosomal protein L33 YP_141034.1 585146 D 299768 CDS YP_141035.1 55822594 3166142 585337..585573 1 NC_006449.1 preprotein translocase subunit SecG 585573 secG 3166142 secG Streptococcus thermophilus CNRZ1066 preprotein translocase subunit SecG YP_141035.1 585337 D 299768 CDS YP_141036.1 55822595 3165918 585632..588085 1 NC_006449.1 exoribonuclease R 588085 rnr 3165918 rnr Streptococcus thermophilus CNRZ1066 exoribonuclease R YP_141036.1 585632 D 299768 CDS YP_141037.1 55822596 3165798 588107..588571 1 NC_006449.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 588571 smpB 3165798 smpB Streptococcus thermophilus CNRZ1066 SsrA-binding protein YP_141037.1 588107 D 299768 CDS YP_141038.1 55822597 3166760 588725..590131 1 NC_006449.1 peptidyl-prolyl cis-trans isomerase 590131 pplB 3166760 pplB Streptococcus thermophilus CNRZ1066 peptidyl-prolyl cis-trans isomerase YP_141038.1 588725 D 299768 CDS YP_141039.1 55822598 3166193 590133..590498 1 NC_006449.1 hypothetical protein 590498 3166193 str0628 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141039.1 590133 D 299768 CDS YP_141040.1 55822599 3166607 complement(590601..591686) 1 NC_006449.1 dipeptidase 591686 pepQ 3166607 pepQ Streptococcus thermophilus CNRZ1066 dipeptidase YP_141040.1 590601 R 299768 CDS YP_141041.1 55822600 3166394 591968..593002 1 NC_006449.1 catabolite control protein 593002 ccpA 3166394 ccpA Streptococcus thermophilus CNRZ1066 catabolite control protein YP_141041.1 591968 D 299768 CDS YP_141042.1 55822601 3165740 593061..593258 1 NC_006449.1 truncated; hypothetical protein 593258 3165740 str0631 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141042.1 593061 D 299768 CDS YP_141043.1 55822602 3165665 593364..594128 1 NC_006449.1 truncated; hypothetical protein 594128 3165665 str0632 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141043.1 593364 D 299768 CDS YP_141044.1 55822603 3165719 594143..595258 1 NC_006449.1 glycerate kinase 595258 grk 3165719 grk Streptococcus thermophilus CNRZ1066 glycerate kinase YP_141044.1 594143 D 299768 CDS YP_141045.1 55822604 3166081 complement(595297..595752) 1 NC_006449.1 hypothetical protein 595752 3166081 str0634 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141045.1 595297 R 299768 CDS YP_141046.1 55822605 3165803 595961..597265 1 NC_006449.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 597265 eno 3165803 eno Streptococcus thermophilus CNRZ1066 phosphopyruvate hydratase YP_141046.1 595961 D 299768 CDS YP_141047.1 55822606 3165660 complement(597763..599949) 1 NC_006449.1 hypothetical protein 599949 3165660 str0636 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141047.1 597763 R 299768 CDS YP_141048.1 55822607 3165842 600110..601273 1 NC_006449.1 hypothetical protein 601273 3165842 str0637 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141048.1 600110 D 299768 CDS YP_141049.1 55822608 3165650 601270..601947 1 NC_006449.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 601947 aroD 3165650 aroD Streptococcus thermophilus CNRZ1066 3-dehydroquinate dehydratase YP_141049.1 601270 D 299768 CDS YP_141050.2 161936372 3165837 601937..602794 1 NC_006449.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 602794 aroE 3165837 aroE Streptococcus thermophilus CNRZ1066 shikimate 5-dehydrogenase YP_141050.2 601937 D 299768 CDS YP_141051.1 55822610 3165640 602807..603874 1 NC_006449.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 603874 aroB 3165640 aroB Streptococcus thermophilus CNRZ1066 3-dehydroquinate synthase YP_141051.1 602807 D 299768 CDS YP_141052.1 55822611 3166694 603875..605041 1 NC_006449.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 605041 aroF 3166694 aroF Streptococcus thermophilus CNRZ1066 chorismate synthase YP_141052.1 603875 D 299768 CDS YP_141053.1 55822612 3166626 605071..606177 1 NC_006449.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 606177 tyrA 3166626 tyrA Streptococcus thermophilus CNRZ1066 prephenate dehydrogenase YP_141053.1 605071 D 299768 CDS YP_141054.1 55822613 3165690 606187..606525 1 NC_006449.1 hypothetical protein 606525 3165690 str0643 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141054.1 606187 D 299768 CDS YP_141055.1 55822614 3165675 606581..607531 1 NC_006449.1 L-2-hydroxyisocaproate dehydrogenase 607531 hdhL 3165675 hdhL Streptococcus thermophilus CNRZ1066 L-2-hydroxyisocaproate dehydrogenase YP_141055.1 606581 D 299768 CDS YP_141056.1 55822615 3165900 607612..608895 1 NC_006449.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 608895 aroA 3165900 aroA Streptococcus thermophilus CNRZ1066 3-phosphoshikimate 1-carboxyvinyltransferase YP_141056.1 607612 D 299768 CDS YP_141057.1 55822616 3165694 608888..609379 1 NC_006449.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 609379 aroK 3165694 aroK Streptococcus thermophilus CNRZ1066 shikimate kinase YP_141057.1 608888 D 299768 CDS YP_141058.1 55822617 3165807 609370..610194 1 NC_006449.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 610194 pheA 3165807 pheA Streptococcus thermophilus CNRZ1066 prephenate dehydratase YP_141058.1 609370 D 299768 CDS YP_141059.1 55822618 3165704 610206..610655 1 NC_006449.1 truncated; negative transcriptional regualtor-PBP synthesis, truncated 610655 3165704 str0648 Streptococcus thermophilus CNRZ1066 negative transcriptional regualtor-PBP synthesis, truncated YP_141059.1 610206 D 299768 CDS YP_141060.1 55822619 3165689 610652..611635 1 NC_006449.1 truncated; negative transcriptional regualtor-PBP synthesis, truncated 611635 3165689 str0649 Streptococcus thermophilus CNRZ1066 negative transcriptional regualtor-PBP synthesis, truncated YP_141060.1 610652 D 299768 CDS YP_141061.1 55822620 3165706 complement(611651..612592) 1 NC_006449.1 exfoliative exotoxin B 612592 eetB 3165706 eetB Streptococcus thermophilus CNRZ1066 exfoliative exotoxin B YP_141061.1 611651 R 299768 CDS YP_141062.1 55822621 3165727 complement(612608..613672) 1 NC_006449.1 hypothetical protein 613672 3165727 str0651 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141062.1 612608 R 299768 CDS YP_141063.1 55822622 3166781 complement(613712..614260) 1 NC_006449.1 macrophage infectivity potentiator-related protein 614260 mip 3166781 mip Streptococcus thermophilus CNRZ1066 macrophage infectivity potentiator-related protein YP_141063.1 613712 R 299768 CDS YP_141064.1 55822623 3165728 614476..615837 1 NC_006449.1 TrmA family tRNA methyltransferase 615837 3165728 str0653 Streptococcus thermophilus CNRZ1066 TrmA family tRNA methyltransferase YP_141064.1 614476 D 299768 CDS YP_141065.1 55822624 3165648 616128..616877 1 NC_006449.1 hypothetical protein 616877 3165648 str0654 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141065.1 616128 D 299768 CDS YP_141066.1 55822625 3166608 617266..617724 1 NC_006449.1 truncated; adenine-specific DNA methyltransferase 617724 3166608 str0655 Streptococcus thermophilus CNRZ1066 adenine-specific DNA methyltransferase YP_141066.1 617266 D 299768 CDS YP_141067.1 55822626 3165666 618321..618932 1 NC_006449.1 hypothetical protein 618932 3165666 str0656 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141067.1 618321 D 299768 CDS YP_141068.1 55822627 3165636 619189..622575 1 NC_006449.1 hypothetical protein 622575 3165636 str0657 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141068.1 619189 D 299768 CDS YP_141069.1 55822628 3165888 622752..623663 1 NC_006449.1 hypothetical protein 623663 3165888 str0658 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141069.1 622752 D 299768 CDS YP_141070.1 55822629 3165741 623665..623988 1 NC_006449.1 hypothetical protein 623988 3165741 str0659 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141070.1 623665 D 299768 CDS YP_141071.1 55822630 3166726 623985..625037 1 NC_006449.1 hypothetical protein 625037 3166726 str0660 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141071.1 623985 D 299768 CDS YP_141072.1 55822631 3165686 complement(627886..628701) 1 NC_006449.1 hypothetical protein 628701 3165686 str0661 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141072.1 627886 R 299768 CDS YP_141073.1 55822632 3166468 complement(628701..629603) 1 NC_006449.1 hypothetical protein 629603 3166468 str0662 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141073.1 628701 R 299768 CDS YP_141074.1 55822633 3165695 629967..632099 1 NC_006449.1 transcriptional regulator 632099 tex 3165695 tex Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141074.1 629967 D 299768 CDS YP_141075.1 55822634 3165893 632086..632526 1 NC_006449.1 hypothetical protein 632526 3165893 str0664 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141075.1 632086 D 299768 CDS YP_141076.1 55822635 3166120 632593..632856 1 NC_006449.1 hypothetical protein 632856 3166120 str0665 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141076.1 632593 D 299768 CDS YP_141077.1 55822636 3165651 632988..633917 1 NC_006449.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 633917 ptsK 3165651 ptsK Streptococcus thermophilus CNRZ1066 HPr kinase/phosphorylase YP_141077.1 632988 D 299768 CDS YP_141078.1 55822637 3166770 633917..634708 1 NC_006449.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 634708 lgt 3166770 lgt Streptococcus thermophilus CNRZ1066 prolipoprotein diacylglyceryl transferase YP_141078.1 633917 D 299768 CDS YP_141079.1 55822638 3166244 634738..635229 1 NC_006449.1 hypothetical protein 635229 3166244 str0668 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141079.1 634738 D 299768 CDS YP_141080.1 55822639 3166275 635242..635676 1 NC_006449.1 hypothetical protein 635676 3166275 str0669 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141080.1 635242 D 299768 CDS YP_141081.1 55822640 3165682 complement(635703..635999) 1 NC_006449.1 hypothetical protein 635999 3165682 str0670 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141081.1 635703 R 299768 CDS YP_141082.1 55822641 3165865 636232..637161 1 NC_006449.1 protease 637161 3165865 str0671 Streptococcus thermophilus CNRZ1066 protease YP_141082.1 636232 D 299768 CDS YP_141083.1 55822642 3165805 637240..638544 1 NC_006449.1 U32 family peptidase 638544 3165805 str0672 Streptococcus thermophilus CNRZ1066 U32 family peptidase YP_141083.1 637240 D 299768 CDS YP_141084.1 55822643 3165949 638544..638792 1 NC_006449.1 hypothetical protein 638792 3165949 str0673 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141084.1 638544 D 299768 CDS YP_141085.1 55822644 3165778 complement(638914..639453) 1 NC_006449.1 biotin synthase 639453 bioY1 3165778 bioY1 Streptococcus thermophilus CNRZ1066 biotin synthase YP_141085.1 638914 R 299768 CDS YP_141086.1 55822645 3165929 complement(639548..639838) 1 NC_006449.1 hypothetical protein 639838 3165929 str0675 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141086.1 639548 R 299768 CDS YP_141087.1 55822646 3165835 639958..640170 1 NC_006449.1 hypothetical protein 640170 3165835 str0676 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141087.1 639958 D 299768 CDS YP_141088.1 55822647 3165725 complement(640207..641550) 1 NC_006449.1 manganese transport protein 641550 mntH 3165725 mntH Streptococcus thermophilus CNRZ1066 manganese transport protein YP_141088.1 640207 R 299768 CDS YP_141089.1 55822648 3166119 641740..642048 1 NC_006449.1 hypothetical protein 642048 3166119 str0678 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141089.1 641740 D 299768 CDS YP_141090.1 55822649 3165902 642067..642540 1 NC_006449.1 MutT/nudix family protein 642540 3165902 str0679 Streptococcus thermophilus CNRZ1066 MutT/nudix family protein YP_141090.1 642067 D 299768 CDS YP_141091.1 55822650 3165844 complement(642563..643099) 1 NC_006449.1 hypothetical protein 643099 3165844 str0680 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141091.1 642563 R 299768 CDS YP_141092.1 55822651 3166761 643508..643873 1 NC_006449.1 hypothetical protein 643873 3166761 str0682 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141092.1 643508 D 299768 CDS YP_141093.1 55822652 3166045 643866..644192 1 NC_006449.1 hypothetical protein 644192 3166045 str0683 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141093.1 643866 D 299768 CDS YP_141094.1 55822653 3166377 644459..645301 1 NC_006449.1 hypothetical protein 645301 3166377 str0684 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141094.1 644459 D 299768 CDS YP_141095.1 55822654 3166174 645381..646340 1 NC_006449.1 hypothetical protein 646340 3166174 str0685 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141095.1 645381 D 299768 CDS YP_141096.1 55822655 3166302 646361..646549 1 NC_006449.1 hypothetical protein 646549 3166302 str0686 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141096.1 646361 D 299768 CDS YP_141097.1 55822656 3166209 646506..646694 1 NC_006449.1 hypothetical protein 646694 3166209 str0687 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141097.1 646506 D 299768 CDS YP_141098.1 55822657 3166395 646934..647251 1 NC_006449.1 hypothetical protein 647251 3166395 str0688 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141098.1 646934 D 299768 CDS YP_141099.1 55822658 3165889 647476..647703 1 NC_006449.1 restriction-modification system regulatory protein 647703 3165889 str0689 Streptococcus thermophilus CNRZ1066 restriction-modification system regulatory protein YP_141099.1 647476 D 299768 CDS YP_141100.1 55822659 3166161 647710..648276 1 NC_006449.1 hypothetical protein 648276 3166161 str0690 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141100.1 647710 D 299768 CDS YP_141101.1 55822660 3166570 648363..649361 1 NC_006449.1 IS1239 transposase 649361 tnp1239 3166570 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_141101.1 648363 D 299768 CDS YP_141102.1 55822661 3165943 complement(649882..651417) 1 NC_006449.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 651417 lysS 3165943 lysS Streptococcus thermophilus CNRZ1066 lysyl-tRNA synthetase YP_141102.1 649882 R 299768 CDS YP_141103.1 55822662 3166060 651743..652006 1 NC_006449.1 hypothetical protein 652006 3166060 str0693 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141103.1 651743 D 299768 CDS YP_141104.1 55822663 3165998 652205..652759 1 NC_006449.1 hypothetical protein 652759 3165998 str0694 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141104.1 652205 D 299768 CDS YP_141105.1 55822664 3165999 652749..653252 1 NC_006449.1 hypothetical protein 653252 3165999 str0695 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141105.1 652749 D 299768 CDS YP_141106.1 55822665 3166074 653576..654478 1 NC_006449.1 hypothetical protein 654478 3166074 str0696 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141106.1 653576 D 299768 CDS YP_141107.1 55822666 3166032 complement(654902..655540) 1 NC_006449.1 phosphoglycerate mutase 655540 gpmC 3166032 gpmC Streptococcus thermophilus CNRZ1066 phosphoglycerate mutase YP_141107.1 654902 R 299768 CDS YP_141108.1 55822667 3166006 complement(655543..656016) 1 NC_006449.1 transcriptional regulator 656016 3166006 str0698 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141108.1 655543 R 299768 CDS YP_141109.1 55822668 3166037 complement(656131..657078) 1 NC_006449.1 endolysin 657078 3166037 str0699 Streptococcus thermophilus CNRZ1066 endolysin YP_141109.1 656131 R 299768 CDS YP_141110.1 55822669 3166002 complement(657270..657659) 1 NC_006449.1 hypothetical protein 657659 3166002 str0700 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141110.1 657270 R 299768 CDS YP_141111.1 55822670 3166098 complement(657915..658541) 1 NC_006449.1 hypothetical protein 658541 3166098 str0701 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141111.1 657915 R 299768 CDS YP_141112.1 55822671 3166178 658788..659069 1 NC_006449.1 hypothetical protein 659069 3166178 str0702 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141112.1 658788 D 299768 CDS YP_141113.1 55822672 3166201 659152..659382 1 NC_006449.1 hypothetical protein 659382 3166201 str0703 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141113.1 659152 D 299768 CDS YP_141114.1 55822673 3166058 659829..660599 1 NC_006449.1 short chain dehydrogenase/reductase family oxidoreductase 660599 3166058 str0704 Streptococcus thermophilus CNRZ1066 short chain dehydrogenase/reductase family oxidoreductase YP_141114.1 659829 D 299768 CDS YP_141115.1 55822674 3166073 660865..663855 1 NC_006449.1 type I restriction-modification system restriction subunit 663855 hsdR1 3166073 hsdR1 Streptococcus thermophilus CNRZ1066 type I restriction-modification system restriction subunit YP_141115.1 660865 D 299768 CDS YP_141116.1 55822675 3166917 663869..665182 1 NC_006449.1 hypothetical protein 665182 3166917 str0706 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141116.1 663869 D 299768 CDS YP_141117.1 55822676 3166773 665479..666378 1 NC_006449.1 hypothetical protein 666378 3166773 str0707 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141117.1 665479 D 299768 CDS YP_141118.1 55822677 3166745 666393..667613 1 NC_006449.1 type I restriction-modification system specificty subunit 667613 hsdS1 3166745 hsdS1 Streptococcus thermophilus CNRZ1066 type I restriction-modification system specificty subunit YP_141118.1 666393 D 299768 CDS YP_141119.1 55822678 3166093 667628..669496 1 NC_006449.1 hypothetical protein 669496 3166093 str0709 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141119.1 667628 D 299768 CDS YP_141120.1 55822679 3165693 669888..670283 1 NC_006449.1 hypothetical protein 670283 3165693 str0710 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141120.1 669888 D 299768 CDS YP_141121.1 55822680 3166068 670326..671930 1 NC_006449.1 type I restriction-modification system methyltransferase subunit 671930 hsdM1 3166068 hsdM1 Streptococcus thermophilus CNRZ1066 type I restriction-modification system methyltransferase subunit YP_141121.1 670326 D 299768 CDS YP_141122.1 55822681 3166407 672137..672337 1 NC_006449.1 hypothetical protein 672337 3166407 str0712 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141122.1 672137 D 299768 CDS YP_141123.1 55822682 3166117 672525..673529 1 NC_006449.1 deoxyribonuclease 673529 3166117 str0713 Streptococcus thermophilus CNRZ1066 deoxyribonuclease YP_141123.1 672525 D 299768 CDS YP_141124.1 55822683 3166101 673680..674240 1 NC_006449.1 cytoplasmic membrane protein 674240 lemA 3166101 lemA Streptococcus thermophilus CNRZ1066 cytoplasmic membrane protein YP_141124.1 673680 D 299768 CDS YP_141125.1 55822684 3166248 674242..675141 1 NC_006449.1 metalloprotease; heat shock protein HtpX 675141 htpX 3166248 htpX Streptococcus thermophilus CNRZ1066 heat shock protein HtpX YP_141125.1 674242 D 299768 CDS YP_141126.1 55822685 3166118 675259..675732 1 NC_006449.1 hypothetical protein 675732 3166118 str0716 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141126.1 675259 D 299768 CDS YP_141127.1 55822686 3166780 675729..676124 1 NC_006449.1 hypothetical protein 676124 3166780 str0717 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141127.1 675729 D 299768 CDS YP_141128.1 55822687 3166121 676298..679120 1 NC_006449.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 679120 ppc 3166121 ppc Streptococcus thermophilus CNRZ1066 phosphoenolpyruvate carboxylase YP_141128.1 676298 D 299768 CDS YP_141129.1 55822688 3166284 679188..680222 1 NC_006449.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 680222 holA 3166284 holA Streptococcus thermophilus CNRZ1066 DNA polymerase III subunit delta YP_141129.1 679188 D 299768 CDS YP_141130.1 55822689 3166154 680260..680922 1 NC_006449.1 superoxide dismutase 680922 sodA 3166154 sodA Streptococcus thermophilus CNRZ1066 superoxide dismutase YP_141130.1 680260 D 299768 CDS YP_141131.1 55822690 3165664 681403..682398 1 NC_006449.1 hypothetical protein 682398 3165664 str0721 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141131.1 681403 D 299768 CDS YP_141132.1 55822691 3166080 complement(682438..683085) 1 NC_006449.1 prepilin peptidase type IV 683085 pilD 3166080 pilD Streptococcus thermophilus CNRZ1066 prepilin peptidase type IV YP_141132.1 682438 R 299768 CDS YP_141133.1 55822692 3166692 683194..683715 1 NC_006449.1 peroxide resistance protein 683715 dpr 3166692 dpr Streptococcus thermophilus CNRZ1066 peroxide resistance protein YP_141133.1 683194 D 299768 CDS YP_141134.1 55822693 3166852 683804..684241 1 NC_006449.1 ferric transport regulator protein 684241 fur 3166852 fur Streptococcus thermophilus CNRZ1066 ferric transport regulator protein YP_141134.1 683804 D 299768 CDS YP_141135.1 55822694 3166132 684352..684558 1 NC_006449.1 hypothetical protein 684558 3166132 str0727 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141135.1 684352 D 299768 CDS YP_141136.1 55822695 3166088 684551..685519 1 NC_006449.1 glucose kinase 685519 glcK 3166088 glcK Streptococcus thermophilus CNRZ1066 glucose kinase YP_141136.1 684551 D 299768 CDS YP_141137.1 55822696 3166177 685657..687504 1 NC_006449.1 GTP-binding protein TypA 687504 typA 3166177 typA Streptococcus thermophilus CNRZ1066 GTP-binding protein TypA YP_141137.1 685657 D 299768 CDS YP_141138.1 55822697 3166278 687528..687800 1 NC_006449.1 hypothetical protein 687800 3166278 str0730 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141138.1 687528 D 299768 CDS YP_141139.1 55822698 3166159 687923..689275 1 NC_006449.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 689275 murD 3166159 murD Streptococcus thermophilus CNRZ1066 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_141139.1 687923 D 299768 CDS YP_141140.1 55822699 3166272 689279..690349 1 NC_006449.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 690349 murG 3166272 murG Streptococcus thermophilus CNRZ1066 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_141140.1 689279 D 299768 CDS YP_141141.1 55822700 3166914 690359..691483 1 NC_006449.1 cell division protein 691483 divIB 3166914 divIB Streptococcus thermophilus CNRZ1066 cell division protein YP_141141.1 690359 D 299768 CDS YP_141142.1 55822701 3166165 691607..692983 1 NC_006449.1 cell division protein 692983 ftsA 3166165 ftsA Streptococcus thermophilus CNRZ1066 cell division protein YP_141142.1 691607 D 299768 CDS YP_141143.1 55822702 3166070 693012..694334 1 NC_006449.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 694334 ftsZ 3166070 ftsZ Streptococcus thermophilus CNRZ1066 cell division protein FtsZ YP_141143.1 693012 D 299768 CDS YP_141144.1 55822703 3166195 694337..695020 1 NC_006449.1 hypothetical protein 695020 3166195 str0736 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141144.1 694337 D 299768 CDS YP_141145.1 55822704 3166171 695025..695594 1 NC_006449.1 hypothetical protein 695594 3166171 str0737 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141145.1 695025 D 299768 CDS YP_141146.1 55822705 3166189 695598..695855 1 NC_006449.1 hypothetical protein 695855 3166189 str0738 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141146.1 695598 D 299768 CDS YP_141147.1 55822706 3166246 695855..696655 1 NC_006449.1 hypothetical protein 696655 3166246 str0739 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141147.1 695855 D 299768 CDS YP_141148.1 55822707 3166222 696899..697774 1 NC_006449.1 cell division initiation protein 697774 divIVA 3166222 divIVA Streptococcus thermophilus CNRZ1066 cell division initiation protein YP_141148.1 696899 D 299768 CDS YP_141149.1 55822708 3166235 698022..700811 1 NC_006449.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 700811 ileS 3166235 ileS Streptococcus thermophilus CNRZ1066 isoleucyl-tRNA synthetase YP_141149.1 698022 D 299768 CDS YP_141150.1 55822709 3166245 complement(701102..701242) 1 NC_006449.1 truncated; truncated IS1193 transposase 701242 3166245 str0742 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141150.1 701102 R 299768 CDS YP_141151.1 55822710 3166183 complement(701196..701432) 1 NC_006449.1 truncated; truncated IS1193 transposase 701432 3166183 str0743 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141151.1 701196 R 299768 CDS YP_141152.1 55822711 3166028 complement(701576..701797) 1 NC_006449.1 truncated; truncated IS1193 transposase 701797 3166028 str0744 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141152.1 701576 R 299768 CDS YP_141153.1 55822712 3166249 702026..703288 1 NC_006449.1 hypothetical protein 703288 3166249 str0745 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141153.1 702026 D 299768 CDS YP_141154.2 161936371 3166146 complement(703412..703654) 1 NC_006449.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 703654 rpmE2 3166146 rpmE2 Streptococcus thermophilus CNRZ1066 50S ribosomal protein L31 YP_141154.2 703412 R 299768 CDS YP_141155.1 55822714 3166268 complement(703760..704698) 1 NC_006449.1 thiamine biosynthesis lipoprotein 704698 apbE 3166268 apbE Streptococcus thermophilus CNRZ1066 thiamine biosynthesis lipoprotein YP_141155.1 703760 R 299768 CDS YP_141156.1 55822715 3166287 complement(704679..705623) 1 NC_006449.1 hypothetical protein 705623 3166287 str0748 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141156.1 704679 R 299768 CDS YP_141157.1 55822716 3166160 complement(705704..706522) 1 NC_006449.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 706522 3166160 str0749 Streptococcus thermophilus CNRZ1066 glutathione S-transferase YghU YP_141157.1 705704 R 299768 CDS YP_141158.1 55822717 3166282 706786..707673 1 NC_006449.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 707673 add 3166282 add Streptococcus thermophilus CNRZ1066 adenosine deaminase YP_141158.1 706786 D 299768 CDS YP_141159.1 55822718 3166411 707901..708491 1 NC_006449.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 708491 tdk 3166411 tdk Streptococcus thermophilus CNRZ1066 thymidine kinase YP_141159.1 707901 D 299768 CDS YP_141160.1 55822719 3166072 708534..709613 1 NC_006449.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 709613 prfA 3166072 prfA Streptococcus thermophilus CNRZ1066 peptide chain release factor 1 YP_141160.1 708534 D 299768 CDS YP_141161.1 55822720 3166308 709610..710443 1 NC_006449.1 protoporphyrinogen oxidase 710443 hemK 3166308 hemK Streptococcus thermophilus CNRZ1066 protoporphyrinogen oxidase YP_141161.1 709610 D 299768 CDS YP_141162.1 55822721 3166151 710430..711035 1 NC_006449.1 Sua5/YciO/YrdC family protein 711035 3166151 str0754 Streptococcus thermophilus CNRZ1066 Sua5/YciO/YrdC family protein YP_141162.1 710430 D 299768 CDS YP_141163.1 55822722 3165802 711130..712380 1 NC_006449.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 712380 glyA 3165802 glyA Streptococcus thermophilus CNRZ1066 serine hydroxymethyltransferase YP_141163.1 711130 D 299768 CDS YP_141164.1 55822723 3166494 712387..713364 1 NC_006449.1 hypothetical protein 713364 3166494 str0756 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141164.1 712387 D 299768 CDS YP_141165.1 55822724 3166527 713312..713977 1 NC_006449.1 hypothetical protein 713977 3166527 str0757 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141165.1 713312 D 299768 CDS YP_141166.1 55822725 3166502 714010..715749 1 NC_006449.1 ABC transporter ATP-binding/permease 715749 3166502 str0758 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding/permease YP_141166.1 714010 D 299768 CDS YP_141167.1 55822726 3166363 715616..717487 1 NC_006449.1 ABC transporter ATP-binding/permease 717487 3166363 str0759 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding/permease YP_141167.1 715616 D 299768 CDS YP_141168.1 55822727 3166918 717529..717795 1 NC_006449.1 component involved in D-alanylation of teichoic acids 717795 dltX 3166918 dltX Streptococcus thermophilus CNRZ1066 component involved in D-alanylation of teichoic acids YP_141168.1 717529 D 299768 CDS YP_141169.1 55822728 3166226 717804..719354 1 NC_006449.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 719354 dltA 3166226 dltA Streptococcus thermophilus CNRZ1066 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_141169.1 717804 D 299768 CDS YP_141170.1 55822729 3166326 719351..720598 1 NC_006449.1 hypothetical protein 720598 dltB 3166326 dltB Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141170.1 719351 D 299768 CDS YP_141171.1 55822730 3166338 720616..720855 1 NC_006449.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 720855 dltC 3166338 dltC Streptococcus thermophilus CNRZ1066 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_141171.1 720616 D 299768 CDS YP_141172.1 55822731 3166369 720848..722116 1 NC_006449.1 hypothetical protein 722116 dltD 3166369 dltD Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141172.1 720848 D 299768 CDS YP_141173.1 55822732 3166364 complement(722169..722387) 1 NC_006449.1 truncated; hypothetical protein 722387 3166364 str0765 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141173.1 722169 R 299768 CDS YP_141174.1 55822733 3165795 complement(722451..722711) 1 NC_006449.1 truncated; hypothetical protein 722711 3165795 str0766 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141174.1 722451 R 299768 CDS YP_141175.1 55822734 3165850 complement(722671..723006) 1 NC_006449.1 truncated; hypothetical protein 723006 3165850 str0767 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141175.1 722671 R 299768 CDS YP_141176.1 55822735 3166681 complement(723000..723248) 1 NC_006449.1 truncated; hypothetical protein 723248 3166681 str0768 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141176.1 723000 R 299768 CDS YP_141177.1 55822736 3165945 complement(723252..723431) 1 NC_006449.1 truncated; hypothetical protein 723431 3165945 str0769 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141177.1 723252 R 299768 CDS YP_141178.1 55822737 3166313 complement(723717..726353) 1 NC_006449.1 calcium transporter P-type ATPase 726353 pacL1 3166313 pacL1 Streptococcus thermophilus CNRZ1066 calcium transporter P-type ATPase YP_141178.1 723717 R 299768 CDS YP_141179.1 55822738 3166396 complement(726530..728248) 1 NC_006449.1 para-aminobenzoate synthetase component I 728248 pabB 3166396 pabB Streptococcus thermophilus CNRZ1066 para-aminobenzoate synthetase component I YP_141179.1 726530 R 299768 CDS YP_141180.1 55822739 3166673 complement(728831..729028) 1 NC_006449.1 hypothetical protein 729028 3166673 str0772 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141180.1 728831 R 299768 CDS YP_141181.1 55822740 3166481 complement(729306..729581) 1 NC_006449.1 hypothetical protein 729581 3166481 str0773 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141181.1 729306 R 299768 CDS YP_141182.1 55822741 3166383 complement(729598..729783) 1 NC_006449.1 hypothetical protein 729783 3166383 str0774 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141182.1 729598 R 299768 CDS YP_141183.1 55822742 3166466 complement(730084..731586) 1 NC_006449.1 DNA primase, phage associated 731586 3166466 str0775 Streptococcus thermophilus CNRZ1066 DNA primase, phage associated YP_141183.1 730084 R 299768 CDS YP_141184.1 55822743 3166317 complement(731576..732436) 1 NC_006449.1 replication protein, phage-plasmid associated 732436 3166317 str0776 Streptococcus thermophilus CNRZ1066 replication protein, phage-plasmid associated YP_141184.1 731576 R 299768 CDS YP_141185.1 55822744 3166351 complement(732451..732723) 1 NC_006449.1 hypothetical protein 732723 3166351 str0777 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141185.1 732451 R 299768 CDS YP_141186.1 55822745 3166392 complement(732725..733066) 1 NC_006449.1 hypothetical protein 733066 3166392 str0778 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141186.1 732725 R 299768 CDS YP_141187.1 55822746 3166546 complement(733053..733289) 1 NC_006449.1 hypothetical protein 733289 3166546 str0779 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141187.1 733053 R 299768 CDS YP_141188.1 55822747 3166718 complement(733501..733881) 1 NC_006449.1 hypothetical protein 733881 3166718 str0780 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141188.1 733501 R 299768 CDS YP_141189.1 55822748 3166352 complement(734016..734246) 1 NC_006449.1 HTH DNA binding protein 734246 3166352 str0781 Streptococcus thermophilus CNRZ1066 HTH DNA binding protein YP_141189.1 734016 R 299768 CDS YP_141190.1 55822749 3166578 734552..735190 1 NC_006449.1 hypothetical protein 735190 3166578 str0782 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141190.1 734552 D 299768 CDS YP_141191.1 55822750 3166441 735270..736436 1 NC_006449.1 integrase/recombinase 736436 int2 3166441 int2 Streptococcus thermophilus CNRZ1066 integrase/recombinase YP_141191.1 735270 D 299768 CDS YP_141192.1 55822751 3166430 736552..736887 1 NC_006449.1 hypothetical protein 736887 3166430 str0784 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141192.1 736552 D 299768 CDS YP_141193.1 55822752 3166451 737176..739464 1 NC_006449.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 739464 metE 3166451 metE Streptococcus thermophilus CNRZ1066 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_141193.1 737176 D 299768 CDS YP_141194.1 55822753 3166452 739593..740528 1 NC_006449.1 5,10-methylenetetrahydrofolate reductase 740528 metF 3166452 metF Streptococcus thermophilus CNRZ1066 5,10-methylenetetrahydrofolate reductase YP_141194.1 739593 D 299768 CDS YP_141195.1 55822754 3166453 complement(740668..742386) 1 NC_006449.1 phosphoglucomutase 742386 pgmA 3166453 pgmA Streptococcus thermophilus CNRZ1066 phosphoglucomutase YP_141195.1 740668 R 299768 CDS YP_141196.1 55822755 3166512 complement(742469..743044) 1 NC_006449.1 hypothetical protein 743044 3166512 str0788 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141196.1 742469 R 299768 CDS YP_141197.1 55822756 3166472 complement(743069..743644) 1 NC_006449.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 743644 dfp1 3166472 dfp1 Streptococcus thermophilus CNRZ1066 phosphopantothenoylcysteine decarboxylase YP_141197.1 743069 R 299768 CDS YP_141198.1 55822757 3166301 complement(743607..744290) 1 NC_006449.1 phosphopantothenate--cysteine ligase 744290 dfp2 3166301 dfp2 Streptococcus thermophilus CNRZ1066 phosphopantothenate--cysteine ligase YP_141198.1 743607 R 299768 CDS YP_141199.1 55822758 3166437 744484..746154 1 NC_006449.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 746154 fhs 3166437 fhs Streptococcus thermophilus CNRZ1066 formate--tetrahydrofolate ligase YP_141199.1 744484 D 299768 CDS YP_141200.1 55822759 3166328 746477..746998 1 NC_006449.1 truncated; response regulator 746998 3166328 str0792 Streptococcus thermophilus CNRZ1066 response regulator YP_141200.1 746477 D 299768 CDS YP_141201.1 55822760 3166461 747002..747301 1 NC_006449.1 truncated; sensor histidine kinase CiaH-like protein, truncated 747301 3166461 str0793 Streptococcus thermophilus CNRZ1066 sensor histidine kinase CiaH-like protein, truncated YP_141201.1 747002 D 299768 CDS YP_141202.1 55822761 3166492 747379..747702 1 NC_006449.1 truncated; sensor histidine kinase CiaH-like protein, truncated 747702 3166492 str0794 Streptococcus thermophilus CNRZ1066 sensor histidine kinase CiaH-like protein, truncated YP_141202.1 747379 D 299768 CDS YP_141203.1 55822762 3166474 747704..748420 1 NC_006449.1 truncated; sensor histidine kinase CiaH-like protein, truncated 748420 3166474 str0795 Streptococcus thermophilus CNRZ1066 sensor histidine kinase CiaH-like protein, truncated YP_141203.1 747704 D 299768 CDS YP_141204.1 55822763 3166482 complement(748490..749359) 1 NC_006449.1 IS3 familytransposase orf2 749359 tnpSth1 3166482 tnpSth1 Streptococcus thermophilus CNRZ1066 IS3 familytransposase orf2 YP_141204.1 748490 R 299768 CDS YP_141205.1 55822764 3166236 complement(749374..750114) 1 NC_006449.1 IS3 familytransposase orf1 750114 tnpSth1 3166236 tnpSth1 Streptococcus thermophilus CNRZ1066 IS3 familytransposase orf1 YP_141205.1 749374 R 299768 CDS YP_141206.2 161936370 3166455 complement(750196..750432) 1 NC_006449.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 750432 rpsT 3166455 rpsT Streptococcus thermophilus CNRZ1066 30S ribosomal protein S20 YP_141206.2 750196 R 299768 CDS YP_141207.1 55822766 3166274 complement(750501..751421) 1 NC_006449.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 751421 coaA 3166274 coaA Streptococcus thermophilus CNRZ1066 pantothenate kinase YP_141207.1 750501 R 299768 CDS YP_141208.1 55822767 3165869 751695..752336 1 NC_006449.1 hypothetical protein 752336 3165869 str0800 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141208.1 751695 D 299768 CDS YP_141209.1 55822768 3166491 752352..752534 1 NC_006449.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 752534 3166491 str0801 Streptococcus thermophilus CNRZ1066 pyrimidine-nucleoside phosphorylase, truncated YP_141209.1 752352 D 299768 CDS YP_141210.1 55822769 3166312 752616..752786 1 NC_006449.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 752786 3166312 str0802 Streptococcus thermophilus CNRZ1066 pyrimidine-nucleoside phosphorylase, truncated YP_141210.1 752616 D 299768 CDS YP_141211.1 55822770 3166449 752767..753153 1 NC_006449.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 753153 3166449 str0803 Streptococcus thermophilus CNRZ1066 pyrimidine-nucleoside phosphorylase, truncated YP_141211.1 752767 D 299768 CDS YP_141212.1 55822771 3166129 753105..753566 1 NC_006449.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 753566 3166129 str0804 Streptococcus thermophilus CNRZ1066 pyrimidine-nucleoside phosphorylase, truncated YP_141212.1 753105 D 299768 CDS YP_141213.1 55822772 3166500 753682..753894 1 NC_006449.1 truncated; deoxyribose-phosphate aldolase, truncated 753894 3166500 str0805 Streptococcus thermophilus CNRZ1066 deoxyribose-phosphate aldolase, truncated YP_141213.1 753682 D 299768 CDS YP_141214.1 55822773 3166470 753906..754301 1 NC_006449.1 truncated; deoxyribose-phosphate aldolase, truncated 754301 3166470 str0806 Streptococcus thermophilus CNRZ1066 deoxyribose-phosphate aldolase, truncated YP_141214.1 753906 D 299768 CDS YP_141215.1 55822774 3166504 754276..754620 1 NC_006449.1 cytidine deaminase 754620 cdd 3166504 cdd Streptococcus thermophilus CNRZ1066 cytidine deaminase YP_141215.1 754276 D 299768 CDS YP_141216.1 55822775 3166507 754809..755819 1 NC_006449.1 hypothetical protein 755819 3166507 str0808 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141216.1 754809 D 299768 CDS YP_141217.1 55822776 3166476 755918..757471 1 NC_006449.1 ABC transporter ATP-binding protein, sugar 757471 3166476 str0809 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding protein, sugar YP_141217.1 755918 D 299768 CDS YP_141218.1 55822777 3166652 757464..758531 1 NC_006449.1 ABC transporter sugar permease 758531 3166652 str0810 Streptococcus thermophilus CNRZ1066 ABC transporter sugar permease YP_141218.1 757464 D 299768 CDS YP_141219.1 55822778 3166561 758533..759489 1 NC_006449.1 ABC transporter sugar permease 759489 3166561 str0811 Streptococcus thermophilus CNRZ1066 ABC transporter sugar permease YP_141219.1 758533 D 299768 CDS YP_141220.1 55822779 3166706 complement(759593..760228) 1 NC_006449.1 hypothetical protein 760228 3166706 str0812 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141220.1 759593 R 299768 CDS YP_141221.1 55822780 3166523 760324..762810 1 NC_006449.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 762810 dinG 3166523 dinG Streptococcus thermophilus CNRZ1066 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_141221.1 760324 D 299768 CDS YP_141222.1 55822782 3166524 complement(762819..763040) 1 NC_006449.1 hypothetical protein 763040 3166524 str0816 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141222.1 762819 R 299768 CDS YP_141223.1 55822781 3166467 763006..763437 1 NC_006449.1 hypothetical protein 763437 3166467 str0815 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141223.1 763006 D 299768 CDS YP_141224.1 55822783 3166535 763442..764623 1 NC_006449.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 764623 aspC1 3166535 aspC1 Streptococcus thermophilus CNRZ1066 aspartate aminotransferase YP_141224.1 763442 D 299768 CDS YP_141225.1 55822784 3166550 764660..766006 1 NC_006449.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 766006 asnC 3166550 asnC Streptococcus thermophilus CNRZ1066 asparaginyl-tRNA synthetase YP_141225.1 764660 D 299768 CDS YP_141226.1 55822785 3166539 766213..766440 1 NC_006449.1 hypothetical protein 766440 3166539 str0819 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141226.1 766213 D 299768 CDS YP_141227.1 55822786 3166597 complement(766504..766626) 1 NC_006449.1 truncated; truncated IS1193 transposase 766626 3166597 str0820 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141227.1 766504 R 299768 CDS YP_141228.1 55822787 3166787 complement(766668..766886) 1 NC_006449.1 truncated; truncated IS1193 transposase 766886 3166787 str0821 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141228.1 766668 R 299768 CDS YP_141229.1 55822788 3166558 complement(766974..767180) 1 NC_006449.1 truncated; truncated IS1193 transposase 767180 3166558 str0822 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141229.1 766974 R 299768 CDS YP_141230.1 55822789 3166548 767522..767902 1 NC_006449.1 translation initiation inhibitor 767902 3166548 str0824 Streptococcus thermophilus CNRZ1066 translation initiation inhibitor YP_141230.1 767522 D 299768 CDS YP_141231.1 55822790 3166712 768076..768729 1 NC_006449.1 hypothetical protein 768729 3166712 str0825 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141231.1 768076 D 299768 CDS YP_141232.1 55822791 3166657 768729..769172 1 NC_006449.1 6-pyruvoyl tetrahydrobiopterin synthase 769172 ptpS 3166657 ptpS Streptococcus thermophilus CNRZ1066 6-pyruvoyl tetrahydrobiopterin synthase YP_141232.1 768729 D 299768 CDS YP_141233.1 55822792 3165762 769165..769881 1 NC_006449.1 coenzyme PQQ synthesis protein 769881 3165762 str0827 Streptococcus thermophilus CNRZ1066 coenzyme PQQ synthesis protein YP_141233.1 769165 D 299768 CDS YP_141234.1 55822793 3166575 769956..770492 1 NC_006449.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 770492 3166575 str0828 Streptococcus thermophilus CNRZ1066 7-cyano-7-deazaguanine reductase YP_141234.1 769956 D 299768 CDS YP_141235.1 55822794 3166436 771312..771500 1 NC_006449.1 hypothetical protein 771500 3166436 str0829 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141235.1 771312 D 299768 CDS YP_141236.1 55822795 3166566 771705..772475 1 NC_006449.1 hypothetical protein 772475 3166566 str0830 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141236.1 771705 D 299768 CDS YP_141237.1 55822796 3166702 772456..773346 1 NC_006449.1 hypothetical protein 773346 3166702 str0831 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141237.1 772456 D 299768 CDS YP_141238.1 55822797 3166584 773343..774317 1 NC_006449.1 hypothetical protein 774317 3166584 str0832 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141238.1 773343 D 299768 CDS YP_141239.1 55822798 3166522 774314..775225 1 NC_006449.1 hypothetical protein 775225 3166522 str0833 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141239.1 774314 D 299768 CDS YP_141240.1 55822799 3166603 775243..775464 1 NC_006449.1 truncated; dipeptidase, truncated 775464 3166603 str0834 Streptococcus thermophilus CNRZ1066 dipeptidase, truncated YP_141240.1 775243 D 299768 CDS YP_141241.1 55822800 3166598 775514..775993 1 NC_006449.1 truncated; dipeptidase, truncated 775993 3166598 str0835 Streptococcus thermophilus CNRZ1066 dipeptidase, truncated YP_141241.1 775514 D 299768 CDS YP_141242.1 55822801 3166182 776000..776236 1 NC_006449.1 truncated; dipeptidase, truncated 776236 3166182 str0836 Streptococcus thermophilus CNRZ1066 dipeptidase, truncated YP_141242.1 776000 D 299768 CDS YP_141243.1 55822802 3165673 776527..776745 1 NC_006449.1 cold shock protein A 776745 cspA 3165673 cspA Streptococcus thermophilus CNRZ1066 cold shock protein A YP_141243.1 776527 D 299768 CDS YP_141244.1 55822803 3166651 776950..777216 1 NC_006449.1 cold shock protein B 777216 cspB 3166651 cspB Streptococcus thermophilus CNRZ1066 cold shock protein B YP_141244.1 776950 D 299768 CDS YP_141245.1 55822804 3166479 777514..778722 1 NC_006449.1 IS1191 transposase 778722 tnp1191 3166479 tnp1191 Streptococcus thermophilus CNRZ1066 IS1191 transposase YP_141245.1 777514 D 299768 CDS YP_141246.1 55822805 3166109 complement(778843..780744) 1 NC_006449.1 cation transporting ATPase, copper transport 780744 copB 3166109 copB Streptococcus thermophilus CNRZ1066 cation transporting ATPase, copper transport YP_141246.1 778843 R 299768 CDS YP_141247.1 55822806 3166480 complement(781214..781714) 1 NC_006449.1 truncated; truncated IS1191 transposase 781714 3166480 str0841 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_141247.1 781214 R 299768 CDS YP_141248.1 55822807 3166588 complement(781882..782421) 1 NC_006449.1 truncated; truncated IS1191 transposase 782421 3166588 str0843 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_141248.1 781882 R 299768 CDS YP_141249.1 55822808 3166683 complement(782468..783493) 1 NC_006449.1 truncated; type I restriction-modification system restriction subunit, truncated 783493 3166683 str0844 Streptococcus thermophilus CNRZ1066 type I restriction-modification system restriction subunit, truncated YP_141249.1 782468 R 299768 CDS YP_141250.1 55822809 3166672 complement(783558..783767) 1 NC_006449.1 hypothetical protein 783767 3166672 str0845 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141250.1 783558 R 299768 CDS YP_141251.1 55822810 3166697 784239..785150 1 NC_006449.1 cysteine synthase 785150 cysM2 3166697 cysM2 Streptococcus thermophilus CNRZ1066 cysteine synthase YP_141251.1 784239 D 299768 CDS YP_141252.1 55822811 3166581 785172..786356 1 NC_006449.1 cystathionine beta-lyase 786356 metB2 3166581 metB2 Streptococcus thermophilus CNRZ1066 cystathionine beta-lyase YP_141252.1 785172 D 299768 CDS YP_141253.1 55822812 3166205 786298..786762 1 NC_006449.1 serine acetyltransferase 786762 cysE2 3166205 cysE2 Streptococcus thermophilus CNRZ1066 serine acetyltransferase YP_141253.1 786298 D 299768 CDS YP_141254.1 55822813 3166777 787408..788586 1 NC_006449.1 IS1191 transposase 788586 tnp1191 3166777 tnp1191 Streptococcus thermophilus CNRZ1066 IS1191 transposase YP_141254.1 787408 D 299768 CDS YP_141255.1 55822814 3166580 complement(789059..789385) 1 NC_006449.1 truncated; type I restriction-modification system specificty subunit, truncated 789385 3166580 str0851 Streptococcus thermophilus CNRZ1066 type I restriction-modification system specificty subunit, truncated YP_141255.1 789059 R 299768 CDS YP_141256.1 55822815 3166707 complement(789382..789759) 1 NC_006449.1 truncated; type I restriction-modification system methyltransferase subunit, truncated 789759 3166707 str0852 Streptococcus thermophilus CNRZ1066 type I restriction-modification system methyltransferase subunit, truncated YP_141256.1 789382 R 299768 CDS YP_141257.1 55822816 3166508 complement(789787..790014) 1 NC_006449.1 truncated; type I restriction-modification system methyltransferase subunit, truncated 790014 3166508 str0853 Streptococcus thermophilus CNRZ1066 type I restriction-modification system methyltransferase subunit, truncated YP_141257.1 789787 R 299768 CDS YP_141258.1 55822817 3166714 790117..790299 1 NC_006449.1 truncated; hypothetical protein 790299 3166714 str0854 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141258.1 790117 D 299768 CDS YP_141259.1 55822818 3166137 790493..791380 1 NC_006449.1 permease 791380 3166137 str0855 Streptococcus thermophilus CNRZ1066 permease YP_141259.1 790493 D 299768 CDS YP_141260.1 55822819 3166693 791996..792190 1 NC_006449.1 truncated; type I restriction-modification system restriction subunit, truncated 792190 3166693 str0856 Streptococcus thermophilus CNRZ1066 type I restriction-modification system restriction subunit, truncated YP_141260.1 791996 D 299768 CDS YP_141261.1 55822820 3166323 792259..792702 1 NC_006449.1 truncated; type I restriction-modification system methyltransferase subunit, truncated 792702 3166323 str0857 Streptococcus thermophilus CNRZ1066 type I restriction-modification system methyltransferase subunit, truncated YP_141261.1 792259 D 299768 CDS YP_141262.1 55822821 3166686 792768..792830 1 NC_006449.1 truncated; dipeptidase, truncated 792830 3166686 str0858 Streptococcus thermophilus CNRZ1066 dipeptidase, truncated YP_141262.1 792768 D 299768 CDS YP_141263.1 55822822 3166741 complement(792992..793651) 1 NC_006449.1 hypothetical protein 793651 3166741 str0859 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141263.1 792992 R 299768 CDS YP_141264.1 55822823 3166688 793867..795411 1 NC_006449.1 zinc ABC transporter substrate binding protein 795411 adcA 3166688 adcA Streptococcus thermophilus CNRZ1066 zinc ABC transporter substrate binding protein YP_141264.1 793867 D 299768 CDS YP_141265.1 55822824 3166744 795629..796027 1 NC_006449.1 hypothetical protein 796027 3166744 str0861 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141265.1 795629 D 299768 CDS YP_141266.1 55822825 3166772 796173..796487 1 NC_006449.1 hypothetical protein 796487 3166772 str0862 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141266.1 796173 D 299768 CDS YP_141267.1 55822826 3166725 complement(796539..797267) 1 NC_006449.1 truncated; hypothetical protein 797267 3166725 str0863 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141267.1 796539 R 299768 CDS YP_141268.1 55822827 3166750 complement(797242..797547) 1 NC_006449.1 truncated; hypothetical protein 797547 3166750 str0865 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141268.1 797242 R 299768 CDS YP_141269.1 55822828 3166526 complement(797522..797650) 1 NC_006449.1 truncated; hypothetical protein 797650 3166526 str0866 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141269.1 797522 R 299768 CDS YP_141270.1 55822829 3166285 797821..797982 1 NC_006449.1 hypothetical protein 797982 3166285 str0867 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141270.1 797821 D 299768 CDS YP_141271.1 55822830 3165647 complement(797968..798975) 1 NC_006449.1 hypothetical protein 798975 3165647 str0868 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141271.1 797968 R 299768 CDS YP_141272.1 55822831 3165726 799150..799860 1 NC_006449.1 peptidoglycan hydrolase 799860 mur2 3165726 mur2 Streptococcus thermophilus CNRZ1066 peptidoglycan hydrolase YP_141272.1 799150 D 299768 CDS YP_141273.1 55822832 3166742 799872..800645 1 NC_006449.1 truncated; hypothetical protein 800645 3166742 str0870 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141273.1 799872 D 299768 CDS YP_141274.1 55822833 3166769 800642..800746 1 NC_006449.1 truncated; hypothetical protein 800746 3166769 str0871 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141274.1 800642 D 299768 CDS YP_141275.1 55822834 3165941 complement(800843..801751) 1 NC_006449.1 metCcysK operon transcriptional activator 801751 cmhR 3165941 cmhR Streptococcus thermophilus CNRZ1066 metCcysK operon transcriptional activator YP_141275.1 800843 R 299768 CDS YP_141276.1 55822835 3166759 801958..803766 1 NC_006449.1 isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 803766 glmS 3166759 glmS Streptococcus thermophilus CNRZ1066 glucosamine--fructose-6-phosphate aminotransferase YP_141276.1 801958 D 299768 CDS YP_141277.1 55822836 3166880 803884..804213 1 NC_006449.1 PhnA-like protein 804213 phnA 3166880 phnA Streptococcus thermophilus CNRZ1066 PhnA-like protein YP_141277.1 803884 D 299768 CDS YP_141278.1 55822837 3166774 804407..805048 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 805048 3166774 str0875 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141278.1 804407 D 299768 CDS YP_141279.1 55822838 3166926 805057..805686 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 805686 3166926 str0876 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_141279.1 805057 D 299768 CDS YP_141280.1 55822839 3165683 805699..806550 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 806550 3165683 str0877 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_141280.1 805699 D 299768 CDS YP_141281.1 55822840 3166752 806735..807133 1 NC_006449.1 truncated; SOS responce UmuC protein, truncated 807133 3166752 str0878 Streptococcus thermophilus CNRZ1066 SOS responce UmuC protein, truncated YP_141281.1 806735 D 299768 CDS YP_141282.1 55822841 3166384 807013..807834 1 NC_006449.1 truncated; SOS responce UmuC protein, truncated 807834 3166384 str0879 Streptococcus thermophilus CNRZ1066 SOS responce UmuC protein, truncated YP_141282.1 807013 D 299768 CDS YP_141283.1 55822842 3166454 808606..808959 1 NC_006449.1 truncated; alcohol dehydrogenase 808959 3166454 str0880 Streptococcus thermophilus CNRZ1066 alcohol dehydrogenase YP_141283.1 808606 D 299768 CDS YP_141284.1 55822843 3166748 808973..809104 1 NC_006449.1 truncated; alcohol dehydrogenase 809104 3166748 str0881 Streptococcus thermophilus CNRZ1066 alcohol dehydrogenase YP_141284.1 808973 D 299768 CDS YP_141285.1 55822844 3166259 809150..809638 1 NC_006449.1 truncated; alcohol dehydrogenase 809638 3166259 str0882 Streptococcus thermophilus CNRZ1066 alcohol dehydrogenase YP_141285.1 809150 D 299768 CDS YP_141286.1 55822845 3166097 809973..810194 1 NC_006449.1 hypothetical protein 810194 3166097 str0883 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141286.1 809973 D 299768 CDS YP_141287.1 55822846 3166771 complement(810262..813048) 1 NC_006449.1 DNA endonuclease, type III restriction and modification system 813048 sthIR 3166771 sthIR Streptococcus thermophilus CNRZ1066 DNA endonuclease, type III restriction and modification system YP_141287.1 810262 R 299768 CDS YP_141288.1 55822847 3166789 complement(813050..814990) 1 NC_006449.1 type III restriction-modification system methylation subunit 814990 sthIM 3166789 sthIM Streptococcus thermophilus CNRZ1066 type III restriction-modification system methylation subunit YP_141288.1 813050 R 299768 CDS YP_141289.1 55822848 3166799 complement(815213..816796) 1 NC_006449.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 816796 guaA 3166799 guaA Streptococcus thermophilus CNRZ1066 GMP synthase YP_141289.1 815213 R 299768 CDS YP_141290.1 55822849 3165867 816944..817642 1 NC_006449.1 GntR family transcriptional regulator 817642 3165867 str0887 Streptococcus thermophilus CNRZ1066 GntR family transcriptional regulator YP_141290.1 816944 D 299768 CDS YP_141291.1 55822850 3165871 817709..818041 1 NC_006449.1 DNA-binding protein 818041 3165871 str0888 Streptococcus thermophilus CNRZ1066 DNA-binding protein YP_141291.1 817709 D 299768 CDS YP_141292.1 55822851 3166331 818074..819636 1 NC_006449.1 signal recognition particle 819636 ffh 3166331 ffh Streptococcus thermophilus CNRZ1066 signal recognition particle YP_141292.1 818074 D 299768 CDS YP_141293.1 55822852 3166929 819678..820265 1 NC_006449.1 hypothetical protein 820265 3166929 str0890 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141293.1 819678 D 299768 CDS YP_141294.1 55822853 3166785 820289..820804 1 NC_006449.1 biotin repressor family transcriptional regulator 820804 3166785 str0891 Streptococcus thermophilus CNRZ1066 biotin repressor family transcriptional regulator YP_141294.1 820289 D 299768 CDS YP_141295.1 55822854 3166563 820899..821588 1 NC_006449.1 transcriptional regulator 821588 3166563 str0892 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141295.1 820899 D 299768 CDS YP_141296.1 55822855 3166857 821716..822570 1 NC_006449.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 822570 rbgA 3166857 rbgA Streptococcus thermophilus CNRZ1066 ribosomal biogenesis GTPase YP_141296.1 821716 D 299768 CDS YP_141297.1 55822856 3165863 822542..823324 1 NC_006449.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 823324 rnhB 3165863 rnhB Streptococcus thermophilus CNRZ1066 ribonuclease HII YP_141297.1 822542 D 299768 CDS YP_141298.1 55822857 3166855 823335..824255 1 NC_006449.1 transcriptional regulator 824255 3166855 str0895 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141298.1 823335 D 299768 CDS YP_141299.1 55822858 3166666 824323..825162 1 NC_006449.1 Smf family DNA processing protein 825162 dprA 3166666 dprA Streptococcus thermophilus CNRZ1066 Smf family DNA processing protein YP_141299.1 824323 D 299768 CDS YP_141300.1 55822859 3166897 825330..827474 1 NC_006449.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 827474 topA 3166897 topA Streptococcus thermophilus CNRZ1066 DNA topoisomerase I YP_141300.1 825330 D 299768 CDS YP_141301.1 55822860 3166459 827591..828415 1 NC_006449.1 hypothetical protein 828415 3166459 str0900 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141301.1 827591 D 299768 CDS YP_141302.1 55822861 3165789 828451..829110 1 NC_006449.1 response regulator 829110 rr04 3165789 rr04 Streptococcus thermophilus CNRZ1066 response regulator YP_141302.1 828451 D 299768 CDS YP_141303.1 55822862 3166599 829101..830495 1 NC_006449.1 sensor histidine kinase SpaK-like protein 830495 hk04 3166599 hk04 Streptococcus thermophilus CNRZ1066 sensor histidine kinase SpaK-like protein YP_141303.1 829101 D 299768 CDS YP_141304.1 55822863 3166755 830596..831939 1 NC_006449.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 831939 gid 3166755 gid Streptococcus thermophilus CNRZ1066 tRNA (uracil-5-)-methyltransferase Gid YP_141304.1 830596 D 299768 CDS YP_141305.1 55822864 3166703 complement(832009..832167) 1 NC_006449.1 truncated; hypothetical protein 832167 3166703 str0904 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141305.1 832009 R 299768 CDS YP_141306.1 55822865 3166624 complement(832204..832995) 1 NC_006449.1 truncated; hypothetical protein 832995 3166624 str0905 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141306.1 832204 R 299768 CDS YP_141307.1 55822866 3166414 833306..833734 1 NC_006449.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 833734 ndk 3166414 ndk Streptococcus thermophilus CNRZ1066 nucleoside diphosphate kinase YP_141307.1 833306 D 299768 CDS YP_141308.1 55822867 3166622 833736..834026 1 NC_006449.1 hypothetical protein 834026 3166622 str0907 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141308.1 833736 D 299768 CDS YP_141309.1 55822868 3166734 834124..834927 1 NC_006449.1 ABC transporter substrate binding protein 834927 3166734 str0908 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein YP_141309.1 834124 D 299768 CDS YP_141310.1 55822869 3166730 835246..835617 1 NC_006449.1 truncated; acetoin reductase, truncated 835617 3166730 str0909 Streptococcus thermophilus CNRZ1066 acetoin reductase, truncated YP_141310.1 835246 D 299768 CDS YP_141311.1 55822870 3166864 835893..836039 1 NC_006449.1 truncated; acetoin reductase, truncated 836039 3166864 str0910 Streptococcus thermophilus CNRZ1066 acetoin reductase, truncated YP_141311.1 835893 D 299768 CDS YP_141312.1 55822871 3166647 836427..838259 1 NC_006449.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 838259 lepA 3166647 lepA Streptococcus thermophilus CNRZ1066 GTP-binding protein LepA YP_141312.1 836427 D 299768 CDS YP_141313.1 55822872 3167478 838666..839007 1 NC_006449.1 hypothetical protein 839007 3167478 str0912 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141313.1 838666 D 299768 CDS YP_141314.1 55822873 3166710 complement(838942..839358) 1 NC_006449.1 hypothetical protein 839358 3166710 str0913 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141314.1 838942 R 299768 CDS YP_141315.1 55822874 3166754 839446..839730 1 NC_006449.1 hypothetical protein 839730 3166754 str0914 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141315.1 839446 D 299768 CDS YP_141316.1 55822875 3166701 839982..840317 1 NC_006449.1 transcriptional regulator 840317 3166701 str0916 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141316.1 839982 D 299768 CDS YP_141317.1 55822876 3165672 840642..841508 1 NC_006449.1 MutR family transcriptional regulator 841508 3165672 str0917 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_141317.1 840642 D 299768 CDS YP_141318.1 55822877 3166859 841568..842368 1 NC_006449.1 hypothetical protein 842368 3166859 str0918 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141318.1 841568 D 299768 CDS YP_141319.1 55822878 3166828 842779..843876 1 NC_006449.1 metallo cofactor biosynthesis protein 843876 3166828 str0920 Streptococcus thermophilus CNRZ1066 metallo cofactor biosynthesis protein YP_141319.1 842779 D 299768 CDS YP_141320.1 55822879 3166016 843873..844616 1 NC_006449.1 agmatinase 844616 speB 3166016 speB Streptococcus thermophilus CNRZ1066 agmatinase YP_141320.1 843873 D 299768 CDS YP_141321.1 55822880 3166898 844647..845795 1 NC_006449.1 hypothetical protein 845795 3166898 str0922 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141321.1 844647 D 299768 CDS YP_141322.1 55822881 3165761 846043..847725 1 NC_006449.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 847725 als 3165761 als Streptococcus thermophilus CNRZ1066 acetolactate synthase YP_141322.1 846043 D 299768 CDS YP_141323.1 55822882 3166729 847741..848460 1 NC_006449.1 alpha-acetolactate decarboxylase 848460 aldB 3166729 aldB Streptococcus thermophilus CNRZ1066 alpha-acetolactate decarboxylase YP_141323.1 847741 D 299768 CDS YP_141324.1 55822883 3166753 complement(848512..848634) 1 NC_006449.1 truncated; hypothetical protein 848634 3166753 str0925 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141324.1 848512 R 299768 CDS YP_141325.1 55822884 3165855 complement(848648..849418) 1 NC_006449.1 truncated; truncated IS1193 transposase 849418 3165855 str0926 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141325.1 848648 R 299768 CDS YP_141326.1 55822885 3166733 complement(849987..850730) 1 NC_006449.1 ABC transporter permease 850730 3166733 str0927 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141326.1 849987 R 299768 CDS YP_141327.1 55822886 3166296 850952..851704 1 NC_006449.1 short chain dehydrogenase/reductase family oxidoreductase 851704 3166296 str0929 Streptococcus thermophilus CNRZ1066 short chain dehydrogenase/reductase family oxidoreductase YP_141327.1 850952 D 299768 CDS YP_141328.1 55822887 3166907 complement(851881..852093) 1 NC_006449.1 hypothetical protein 852093 3166907 str0930 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141328.1 851881 R 299768 CDS YP_141329.1 55822888 3166700 complement(852132..852671) 1 NC_006449.1 TetR family transcriptional regulator 852671 3166700 str0931 Streptococcus thermophilus CNRZ1066 TetR family transcriptional regulator YP_141329.1 852132 R 299768 CDS YP_141330.1 55822889 3166553 852805..853701 1 NC_006449.1 cation efflux protein 853701 3166553 str0932 Streptococcus thermophilus CNRZ1066 cation efflux protein YP_141330.1 852805 D 299768 CDS YP_141331.1 55822890 3166845 853813..853965 1 NC_006449.1 truncated; ferrochelatase 853965 3166845 str0933 Streptococcus thermophilus CNRZ1066 ferrochelatase YP_141331.1 853813 D 299768 CDS YP_141332.1 55822891 3166827 853991..854302 1 NC_006449.1 truncated; ferrochelatase 854302 3166827 str0934 Streptococcus thermophilus CNRZ1066 ferrochelatase YP_141332.1 853991 D 299768 CDS YP_141333.1 55822892 3165644 854303..855085 1 NC_006449.1 truncated; ferrochelatase 855085 3165644 str0935 Streptococcus thermophilus CNRZ1066 ferrochelatase YP_141333.1 854303 D 299768 CDS YP_141334.1 55822893 3166179 855294..856220 1 NC_006449.1 alcohol dehydrogenase 856220 adhB 3166179 adhB Streptococcus thermophilus CNRZ1066 alcohol dehydrogenase YP_141334.1 855294 D 299768 CDS YP_141335.1 55822894 3166168 856633..856812 1 NC_006449.1 truncated; hypothetical protein 856812 3166168 str0937 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141335.1 856633 D 299768 CDS YP_141336.1 55822895 3166749 856891..857340 1 NC_006449.1 truncated; hypothetical protein 857340 3166749 str0938 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141336.1 856891 D 299768 CDS YP_141337.1 55822896 3166850 857503..857805 1 NC_006449.1 hypothetical protein 857805 3166850 str0939 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141337.1 857503 D 299768 CDS YP_141338.1 55822897 3166851 857802..858254 1 NC_006449.1 hypothetical protein 858254 3166851 str0940 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141338.1 857802 D 299768 CDS YP_141339.1 55822898 3165877 858600..859364 1 NC_006449.1 phosphorylase Pnp/Udp family protein 859364 3165877 str0941 Streptococcus thermophilus CNRZ1066 phosphorylase Pnp/Udp family protein YP_141339.1 858600 D 299768 CDS YP_141340.1 55822899 3166902 complement(859426..860073) 1 NC_006449.1 phosphatase 860073 3166902 str0942 Streptococcus thermophilus CNRZ1066 phosphatase YP_141340.1 859426 R 299768 CDS YP_141341.1 55822900 3166676 860349..860480 1 NC_006449.1 truncated; ferrichrome ABC transporter substrate-binding protein 860480 3166676 str0943 Streptococcus thermophilus CNRZ1066 ferrichrome ABC transporter substrate-binding protein YP_141341.1 860349 D 299768 CDS YP_141342.1 55822901 3166866 860523..860798 1 NC_006449.1 hypothetical protein 860798 3166866 str0944 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141342.1 860523 D 299768 CDS YP_141343.1 55822902 3166840 complement(860795..861118) 1 NC_006449.1 truncated; MATE efflux family protein DinF, truncated 861118 3166840 str0945 Streptococcus thermophilus CNRZ1066 MATE efflux family protein DinF, truncated YP_141343.1 860795 R 299768 CDS YP_141344.1 55822903 3166258 complement(861076..861342) 1 NC_006449.1 truncated; MATE efflux family protein DinF, truncated 861342 3166258 str0946 Streptococcus thermophilus CNRZ1066 MATE efflux family protein DinF, truncated YP_141344.1 861076 R 299768 CDS YP_141345.1 55822904 3166863 complement(861339..861806) 1 NC_006449.1 truncated; MATE efflux family protein DinF, truncated 861806 3166863 str0947 Streptococcus thermophilus CNRZ1066 MATE efflux family protein DinF, truncated YP_141345.1 861339 R 299768 CDS YP_141346.1 55822905 3166919 complement(861937..862185) 1 NC_006449.1 truncated; MATE efflux family protein DinF, truncated 862185 3166919 str0948 Streptococcus thermophilus CNRZ1066 MATE efflux family protein DinF, truncated YP_141346.1 861937 R 299768 CDS YP_141347.1 55822906 3166641 862385..862594 1 NC_006449.1 hypothetical protein 862594 3166641 str0949 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141347.1 862385 D 299768 CDS YP_141348.1 55822907 3166923 complement(862970..864628) 1 NC_006449.1 fibronectin-binding protein-like protein A 864628 fbp 3166923 fbp Streptococcus thermophilus CNRZ1066 fibronectin-binding protein-like protein A YP_141348.1 862970 R 299768 CDS YP_141349.1 55822908 3165913 864946..865503 1 NC_006449.1 hypothetical protein 865503 3165913 str0951 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141349.1 864946 D 299768 CDS YP_141350.1 55822909 3166816 865504..865728 1 NC_006449.1 hypothetical protein 865728 3166816 str0952 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141350.1 865504 D 299768 CDS YP_141351.1 55822910 3166899 865770..866318 1 NC_006449.1 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme 866318 thiJ 3166899 thiJ Streptococcus thermophilus CNRZ1066 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme YP_141351.1 865770 D 299768 CDS YP_141352.1 55822911 3165927 866560..867363 1 NC_006449.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 867363 pyrK 3165927 pyrK Streptococcus thermophilus CNRZ1066 dihydroorotate dehydrogenase electron transfer subunit YP_141352.1 866560 D 299768 CDS YP_141353.1 55822912 3165654 867382..868329 1 NC_006449.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 868329 pyrDb 3165654 pyrDb Streptococcus thermophilus CNRZ1066 dihydroorotate dehydrogenase 1B YP_141353.1 867382 D 299768 CDS YP_141354.1 55822913 3166909 868468..869091 1 NC_006449.1 hypothetical protein 869091 3166909 str0956 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141354.1 868468 D 299768 CDS YP_141355.1 55822914 3166847 869076..869471 1 NC_006449.1 hypothetical protein 869471 3166847 str0957 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141355.1 869076 D 299768 CDS YP_141356.1 55822915 3166185 869529..869801 1 NC_006449.1 hypothetical protein 869801 3166185 str0958 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141356.1 869529 D 299768 CDS YP_141357.1 55822916 3166900 869951..870613 1 NC_006449.1 hypothetical protein 870613 3166900 str0962 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141357.1 869951 D 299768 CDS YP_141358.1 55822917 3166894 870615..871514 1 NC_006449.1 hypothetical protein 871514 3166894 str0963 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141358.1 870615 D 299768 CDS YP_141359.1 55822918 3166530 871517..872590 1 NC_006449.1 hypothetical protein 872590 3166530 str0964 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141359.1 871517 D 299768 CDS YP_141360.1 55822919 3166841 872744..873943 1 NC_006449.1 hypothetical protein 873943 3166841 str0965 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141360.1 872744 D 299768 CDS YP_141361.1 55822920 3166868 874118..874813 1 NC_006449.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 874813 pyrF 3166868 pyrF Streptococcus thermophilus CNRZ1066 orotidine 5'-phosphate decarboxylase YP_141361.1 874118 D 299768 CDS YP_141362.1 55822921 3166872 874902..875531 1 NC_006449.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 875531 pyrE 3166872 pyrE Streptococcus thermophilus CNRZ1066 orotate phosphoribosyltransferase YP_141362.1 874902 D 299768 CDS YP_141363.1 55822922 3166922 875772..876179 1 NC_006449.1 truncated; amidase 876179 3166922 str0969 Streptococcus thermophilus CNRZ1066 amidase YP_141363.1 875772 D 299768 CDS YP_141364.1 55822923 3166853 complement(876230..877681) 1 NC_006449.1 di-/tripeptide transporter 877681 dtpT 3166853 dtpT Streptococcus thermophilus CNRZ1066 di-/tripeptide transporter YP_141364.1 876230 R 299768 CDS YP_141365.1 55822924 3165658 878062..878409 1 NC_006449.1 truncated; truncated IS1239 transposase 878409 3165658 str0971 Streptococcus thermophilus CNRZ1066 truncated IS1239 transposase YP_141365.1 878062 D 299768 CDS YP_141366.1 55822925 3166824 878381..879061 1 NC_006449.1 truncated; truncated IS1239 transposase 879061 3166824 str0972 Streptococcus thermophilus CNRZ1066 truncated IS1239 transposase YP_141366.1 878381 D 299768 CDS YP_141367.1 55822926 3166933 879347..879949 1 NC_006449.1 truncated; amidase 879949 3166933 str0973 Streptococcus thermophilus CNRZ1066 amidase YP_141367.1 879347 D 299768 CDS YP_141368.1 55822927 3166810 880038..880472 1 NC_006449.1 truncated; ABC transporter substrate binding protein, truncated 880472 3166810 str0974 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein, truncated YP_141368.1 880038 D 299768 CDS YP_141369.1 55822928 3165920 880492..880851 1 NC_006449.1 truncated; ABC transporter substrate binding protein, truncated 880851 3165920 str0975 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein, truncated YP_141369.1 880492 D 299768 CDS YP_141370.1 55822929 3165861 880990..881403 1 NC_006449.1 truncated; ABC transporter permease, truncated 881403 3165861 str0976 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_141370.1 880990 D 299768 CDS YP_141371.1 55822930 3165635 881373..881561 1 NC_006449.1 truncated; ABC transporter permease, truncated 881561 3165635 str0977 Streptococcus thermophilus CNRZ1066 ABC transporter permease, truncated YP_141371.1 881373 D 299768 CDS YP_141372.1 55822931 3165780 881691..881924 1 NC_006449.1 hypothetical protein 881924 3165780 str0978 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141372.1 881691 D 299768 CDS YP_141373.1 55822932 3166288 881998..883464 1 NC_006449.1 5'-nucleotidase 883464 3166288 str0979 Streptococcus thermophilus CNRZ1066 5'-nucleotidase YP_141373.1 881998 D 299768 CDS YP_141374.1 55822933 3166300 883475..883762 1 NC_006449.1 hypothetical protein 883762 3166300 str0980 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141374.1 883475 D 299768 CDS YP_141375.1 55822934 3166004 complement(883972..884577) 1 NC_006449.1 truncated; AraC family transcriptional regulator 884577 3166004 str0981 Streptococcus thermophilus CNRZ1066 AraC family transcriptional regulator YP_141375.1 883972 R 299768 CDS YP_141376.1 55822935 3165873 complement(884734..884877) 1 NC_006449.1 truncated; AraC family transcriptional regulator 884877 3165873 str0982 Streptococcus thermophilus CNRZ1066 AraC family transcriptional regulator YP_141376.1 884734 R 299768 CDS YP_141377.1 55822936 3166083 complement(885053..886423) 1 NC_006449.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 886423 trmE 3166083 trmE Streptococcus thermophilus CNRZ1066 tRNA modification GTPase TrmE YP_141377.1 885053 R 299768 CDS YP_141378.1 55822937 3165676 complement(886552..887895) 1 NC_006449.1 sodium/alanine glycine symporter 887895 dagA 3165676 dagA Streptococcus thermophilus CNRZ1066 sodium/alanine glycine symporter YP_141378.1 886552 R 299768 CDS YP_141379.1 55822938 3166475 887993..888241 1 NC_006449.1 hypothetical protein 888241 3166475 str0985 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141379.1 887993 D 299768 CDS YP_141380.1 55822939 3166277 888393..890720 1 NC_006449.1 ATP-dependent DNA helicase 890720 pcrA 3166277 pcrA Streptococcus thermophilus CNRZ1066 ATP-dependent DNA helicase YP_141380.1 888393 D 299768 CDS YP_141381.1 55822940 3166155 890808..892121 1 NC_006449.1 O-acetylhomoserine sulfhydrylase 892121 cysD 3166155 cysD Streptococcus thermophilus CNRZ1066 O-acetylhomoserine sulfhydrylase YP_141381.1 890808 D 299768 CDS YP_141382.1 55822941 3166153 892182..892523 1 NC_006449.1 truncated; hypothetical protein 892523 3166153 str0988 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141382.1 892182 D 299768 CDS YP_141383.1 55822942 3166832 892569..892937 1 NC_006449.1 truncated; hypothetical protein 892937 3166832 str0989 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141383.1 892569 D 299768 CDS YP_141384.1 55822943 3166243 893002..893496 1 NC_006449.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 893496 tpx 3166243 tpx Streptococcus thermophilus CNRZ1066 thiol peroxidase YP_141384.1 893002 D 299768 CDS YP_141385.1 55822944 3166022 893619..894239 1 NC_006449.1 type I restriction-modification system specificty subunit 894239 hsdS2 3166022 hsdS2 Streptococcus thermophilus CNRZ1066 type I restriction-modification system specificty subunit YP_141385.1 893619 D 299768 CDS YP_141386.1 55822945 3165829 894260..894463 1 NC_006449.1 hypothetical protein 894463 3165829 str0992 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141386.1 894260 D 299768 CDS YP_141387.1 55822946 3166618 894477..895793 1 NC_006449.1 hypothetical protein 895793 3166618 str0993 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141387.1 894477 D 299768 CDS YP_141388.1 55822947 3166768 895915..896796 1 NC_006449.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 896796 truB 3166768 truB Streptococcus thermophilus CNRZ1066 tRNA pseudouridine synthase B YP_141388.1 895915 D 299768 CDS YP_141389.1 55822948 3166418 896793..897704 1 NC_006449.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 897704 ribC 3166418 ribC Streptococcus thermophilus CNRZ1066 bifunctional riboflavin kinase/FMN adenylyltransferase YP_141389.1 896793 D 299768 CDS YP_141390.1 55822949 3166627 897775..898188 1 NC_006449.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 898188 spxA 3166627 spxA Streptococcus thermophilus CNRZ1066 transcriptional regulator Spx YP_141390.1 897775 D 299768 CDS YP_141391.1 55822950 3166237 898181..898462 1 NC_006449.1 hypothetical protein 898462 3166237 str0998 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141391.1 898181 D 299768 CDS YP_141392.1 55822951 3166164 898452..899219 1 NC_006449.1 inositol monophosphatase 899219 suhB 3166164 suhB Streptococcus thermophilus CNRZ1066 inositol monophosphatase YP_141392.1 898452 D 299768 CDS YP_141393.1 55822952 3165946 899271..900611 1 NC_006449.1 rRNA methyltransferase 900611 3165946 str1000 Streptococcus thermophilus CNRZ1066 rRNA methyltransferase YP_141393.1 899271 D 299768 CDS YP_141394.1 55822953 3166590 900712..901611 1 NC_006449.1 phosphate ABC transporter substrate binding protein 901611 pstS 3166590 pstS Streptococcus thermophilus CNRZ1066 phosphate ABC transporter substrate binding protein YP_141394.1 900712 D 299768 CDS YP_141395.1 55822954 3166021 901614..902528 1 NC_006449.1 phosphate ABC transporter permease 902528 pstC1 3166021 pstC1 Streptococcus thermophilus CNRZ1066 phosphate ABC transporter permease YP_141395.1 901614 D 299768 CDS YP_141396.1 55822955 3165754 902500..903402 1 NC_006449.1 phosphate ABC transporter permease 903402 pstC2 3165754 pstC2 Streptococcus thermophilus CNRZ1066 phosphate ABC transporter permease YP_141396.1 902500 D 299768 CDS YP_141397.1 55822956 3165717 903413..904216 1 NC_006449.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 904216 pstB1 3165717 pstB1 Streptococcus thermophilus CNRZ1066 phosphate transporter ATP-binding protein YP_141397.1 903413 D 299768 CDS YP_141398.1 55822957 3166737 904229..904987 1 NC_006449.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 904987 pstB2 3166737 pstB2 Streptococcus thermophilus CNRZ1066 phosphate transporter ATP-binding protein YP_141398.1 904229 D 299768 CDS YP_141399.1 55822958 3165766 905012..905668 1 NC_006449.1 phosphate uptake regulatory protein 905668 phoU 3165766 phoU Streptococcus thermophilus CNRZ1066 phosphate uptake regulatory protein YP_141399.1 905012 D 299768 CDS YP_141400.1 55822959 3166020 905802..908342 1 NC_006449.1 lysyl-aminopeptidase, aminopeptidase N 908342 pepN 3166020 pepN Streptococcus thermophilus CNRZ1066 lysyl-aminopeptidase, aminopeptidase N YP_141400.1 905802 D 299768 CDS YP_141401.1 55822960 3165742 complement(908504..909574) 1 NC_006449.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 909574 xerS 3165742 xerS Streptococcus thermophilus CNRZ1066 site-specific tyrosine recombinase XerS YP_141401.1 908504 R 299768 CDS YP_141402.1 55822961 3165747 complement(909799..910788) 1 NC_006449.1 lipoate-protein ligase 910788 lplA 3165747 lplA Streptococcus thermophilus CNRZ1066 lipoate-protein ligase YP_141402.1 909799 R 299768 CDS YP_141403.1 55822962 3165827 910971..911525 1 NC_006449.1 hypothetical protein 911525 3165827 str1010 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141403.1 910971 D 299768 CDS YP_141404.1 55822963 3165825 911594..912022 1 NC_006449.1 hypothetical protein 912022 3165825 str1011 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141404.1 911594 D 299768 CDS YP_141405.1 55822964 3165698 complement(912128..914392) 1 NC_006449.1 glycogen phosphorylase 914392 glgP 3165698 glgP Streptococcus thermophilus CNRZ1066 glycogen phosphorylase YP_141405.1 912128 R 299768 CDS YP_141406.1 55822965 3165755 complement(914394..915893) 1 NC_006449.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 915893 malQ 3165755 malQ Streptococcus thermophilus CNRZ1066 4-alpha-glucanotransferase YP_141406.1 914394 R 299768 CDS YP_141407.1 55822966 3165680 complement(916077..917081) 1 NC_006449.1 maltose operon transcriptional repressor 917081 malR 3165680 malR Streptococcus thermophilus CNRZ1066 maltose operon transcriptional repressor YP_141407.1 916077 R 299768 CDS YP_141408.1 55822967 3165770 917428..917550 1 NC_006449.1 truncated; maltose ABC transporter substrate-binding protein 917550 3165770 str1015 Streptococcus thermophilus CNRZ1066 maltose ABC transporter substrate-binding protein YP_141408.1 917428 D 299768 CDS YP_141409.1 55822968 3165724 917934..918125 1 NC_006449.1 truncated; maltose ABC transporter substrate-binding protein 918125 3165724 str1016 Streptococcus thermophilus CNRZ1066 maltose ABC transporter substrate-binding protein YP_141409.1 917934 D 299768 CDS YP_141410.1 55822969 3165735 918139..918495 1 NC_006449.1 truncated; maltose ABC transporter permease 918495 3165735 str1017 Streptococcus thermophilus CNRZ1066 maltose ABC transporter permease YP_141410.1 918139 D 299768 CDS YP_141411.1 55822970 3165674 918438..919061 1 NC_006449.1 truncated; maltose/maltodextrin ABC transporter / tnp1167 hybrid protein, truncated 919061 3165674 str1018 Streptococcus thermophilus CNRZ1066 maltose/maltodextrin ABC transporter / tnp1167 hybrid protein, truncated YP_141411.1 918438 D 299768 CDS YP_141412.1 55822971 3165641 919227..919325 1 NC_006449.1 hypothetical protein 919325 3165641 str1019 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141412.1 919227 D 299768 CDS YP_141413.1 55822972 3165637 complement(919463..919651) 1 NC_006449.1 Sec-independent protein translocase protein TatA 919651 tatA 3165637 tatA Streptococcus thermophilus CNRZ1066 Sec-independent protein translocase protein TatA YP_141413.1 919463 R 299768 CDS YP_141414.1 55822973 3165634 complement(919664..920392) 1 NC_006449.1 Sec-independent protein translocase protein TatC 920392 tatC 3165634 tatC Streptococcus thermophilus CNRZ1066 Sec-independent protein translocase protein TatC YP_141414.1 919664 R 299768 CDS YP_141415.1 55822974 3165633 complement(920379..922100) 1 NC_006449.1 hypothetical protein 922100 3165633 str1022 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141415.1 920379 R 299768 CDS YP_141416.1 55822975 3165854 complement(922042..923247) 1 NC_006449.1 hypothetical protein 923247 3165854 str1023 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141416.1 922042 R 299768 CDS YP_141417.1 55822976 3165732 complement(923253..924080) 1 NC_006449.1 hypothetical protein 924080 3165732 str1024 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141417.1 923253 R 299768 CDS YP_141418.1 55822977 3166103 complement(924387..925433) 1 NC_006449.1 ferrichrome ABC transporter substrate-binding protein 925433 fatB 3166103 fatB Streptococcus thermophilus CNRZ1066 ferrichrome ABC transporter substrate-binding protein YP_141418.1 924387 R 299768 CDS YP_141419.1 55822978 3166829 complement(925445..926200) 1 NC_006449.1 ferrichrome ABC transporter ATP-binding protein 926200 fatA 3166829 fatA Streptococcus thermophilus CNRZ1066 ferrichrome ABC transporter ATP-binding protein YP_141419.1 925445 R 299768 CDS YP_141420.1 55822979 3165652 complement(926197..927183) 1 NC_006449.1 ferrichrome ABC transporter permease 927183 fatC 3165652 fatC Streptococcus thermophilus CNRZ1066 ferrichrome ABC transporter permease YP_141420.1 926197 R 299768 CDS YP_141421.1 55822980 3165662 complement(927162..928136) 1 NC_006449.1 ferrichrome ABC transporter permease 928136 fatD 3165662 fatD Streptococcus thermophilus CNRZ1066 ferrichrome ABC transporter permease YP_141421.1 927162 R 299768 CDS YP_141422.1 55822981 3166204 complement(928614..928919) 1 NC_006449.1 truncated; alkaline amylopullulanase, truncated 928919 3166204 str1029 Streptococcus thermophilus CNRZ1066 alkaline amylopullulanase, truncated YP_141422.1 928614 R 299768 CDS YP_141423.1 55822982 3165847 complement(928916..929065) 1 NC_006449.1 truncated; alkaline amylopullulanase, truncated 929065 3165847 str1030 Streptococcus thermophilus CNRZ1066 alkaline amylopullulanase, truncated YP_141423.1 928916 R 299768 CDS YP_141424.1 55822983 3165832 complement(929150..929293) 1 NC_006449.1 truncated; alkaline amylopullulanase, truncated 929293 3165832 str1031 Streptococcus thermophilus CNRZ1066 alkaline amylopullulanase, truncated YP_141424.1 929150 R 299768 CDS YP_141425.1 55822984 3165845 complement(929455..930681) 1 NC_006449.1 truncated; alkaline amylopullulanase, truncated 930681 3165845 str1032 Streptococcus thermophilus CNRZ1066 alkaline amylopullulanase, truncated YP_141425.1 929455 R 299768 CDS YP_141426.1 55822985 3165848 complement(930700..930804) 1 NC_006449.1 truncated; alkaline amylopullulanase, truncated 930804 3165848 str1034 Streptococcus thermophilus CNRZ1066 alkaline amylopullulanase, truncated YP_141426.1 930700 R 299768 CDS YP_141427.1 55822986 3165853 931092..931451 1 NC_006449.1 truncated; truncated IS1191 transposase 931451 3165853 str1035 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_141427.1 931092 D 299768 CDS YP_141428.1 55822987 3165872 931484..932290 1 NC_006449.1 truncated; truncated IS1191 transposase 932290 3165872 str1036 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_141428.1 931484 D 299768 CDS YP_141429.1 55822988 3165860 932595..932783 1 NC_006449.1 hypothetical protein 932783 3165860 str1037 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141429.1 932595 D 299768 CDS YP_141430.1 55822989 3165901 932776..933021 1 NC_006449.1 hypothetical protein 933021 3165901 str1038 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141430.1 932776 D 299768 CDS YP_141431.1 55822990 3165915 complement(933008..934006) 1 NC_006449.1 IS1239 transposase 934006 tnp1239 3165915 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_141431.1 933008 R 299768 CDS YP_141432.1 55822991 3166000 complement(934093..935493) 1 NC_006449.1 hypothetical protein 935493 3166000 str1040 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141432.1 934093 R 299768 CDS YP_141433.1 55822992 3165879 complement(935480..936499) 1 NC_006449.1 UDP-N-acetylglucosamine enolpyruvyl transferase 936499 3165879 str1041 Streptococcus thermophilus CNRZ1066 UDP-N-acetylglucosamine enolpyruvyl transferase YP_141433.1 935480 R 299768 CDS YP_141434.1 55822993 3165788 complement(936567..937133) 1 NC_006449.1 hypothetical protein 937133 3165788 str1042 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141434.1 936567 R 299768 CDS YP_141435.1 55822994 3166665 complement(937927..938835) 1 NC_006449.1 tyrosyl-tRNA synthetase E 938835 tyrSE 3166665 tyrSE Streptococcus thermophilus CNRZ1066 tyrosyl-tRNA synthetase E YP_141435.1 937927 R 299768 CDS YP_141436.1 55822995 3165922 939089..939943 1 NC_006449.1 MutR family transcriptional regulator 939943 3165922 str1044 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_141436.1 939089 D 299768 CDS YP_141437.1 55822996 3166133 complement(940110..941366) 1 NC_006449.1 IS1193 transposase 941366 tnp1193 3166133 tnp1193 Streptococcus thermophilus CNRZ1066 IS1193 transposase YP_141437.1 940110 R 299768 CDS YP_141438.1 55822997 3166092 complement(941851..942246) 1 NC_006449.1 truncated; endolysin , truncated 942246 3166092 str1046 Streptococcus thermophilus CNRZ1066 endolysin , truncated YP_141438.1 941851 R 299768 CDS YP_141439.1 55822998 3165779 complement(942362..942676) 1 NC_006449.1 hypothetical protein 942676 3165779 str1047 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141439.1 942362 R 299768 CDS YP_141440.1 55822999 3166229 complement(942954..944708) 1 NC_006449.1 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 944708 acoL 3166229 acoL Streptococcus thermophilus CNRZ1066 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase YP_141440.1 942954 R 299768 CDS YP_141441.1 55823000 3166110 complement(944879..946267) 1 NC_006449.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 946267 acoC 3166110 acoC Streptococcus thermophilus CNRZ1066 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_141441.1 944879 R 299768 CDS YP_141442.1 55823001 3166322 complement(946425..947438) 1 NC_006449.1 acetoin dehydrogenase complex, E1 component subunit beta 947438 acoB 3166322 acoB Streptococcus thermophilus CNRZ1066 acetoin dehydrogenase complex, E1 component subunit beta YP_141442.1 946425 R 299768 CDS YP_141443.1 55823002 3167306 complement(947448..948419) 1 NC_006449.1 acetoin dehydrogenase complex, E1 component subunit alpha 948419 acoA 3167306 acoA Streptococcus thermophilus CNRZ1066 acetoin dehydrogenase complex, E1 component subunit alpha YP_141443.1 947448 R 299768 CDS YP_141444.1 55823003 3166572 complement(948909..949217) 1 NC_006449.1 truncated; hypothetical protein 949217 3166572 str1052 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141444.1 948909 R 299768 CDS YP_141445.1 55823004 3166574 complement(949473..949994) 1 NC_006449.1 truncated; hypothetical protein 949994 3166574 str1053 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141445.1 949473 R 299768 CDS YP_141446.1 55823005 3166617 complement(950186..951454) 1 NC_006449.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 951454 pyrC 3166617 pyrC Streptococcus thermophilus CNRZ1066 dihydroorotase YP_141446.1 950186 R 299768 CDS YP_141447.1 55823006 3166620 complement(951474..952154) 1 NC_006449.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 952154 ung 3166620 ung Streptococcus thermophilus CNRZ1066 uracil-DNA glycosylase YP_141447.1 951474 R 299768 CDS YP_141448.1 55823007 3165907 952341..953537 1 NC_006449.1 cation efflux protein 953537 3165907 str1056 Streptococcus thermophilus CNRZ1066 cation efflux protein YP_141448.1 952341 D 299768 CDS YP_141449.1 55823008 3166631 953810..953977 1 NC_006449.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 953977 3166631 str1057 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_141449.1 953810 D 299768 CDS YP_141450.1 55823009 3166594 953958..954140 1 NC_006449.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 954140 3166594 str1058 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_141450.1 953958 D 299768 CDS YP_141451.1 55823010 3165859 954162..955103 1 NC_006449.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 955103 3165859 str1059 Streptococcus thermophilus CNRZ1066 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_141451.1 954162 D 299768 CDS YP_141452.1 55823011 3166593 complement(955143..955994) 1 NC_006449.1 phosphoesterase 955994 3166593 str1060 Streptococcus thermophilus CNRZ1066 phosphoesterase YP_141452.1 955143 R 299768 CDS YP_141453.1 55823012 3166662 complement(955991..956479) 1 NC_006449.1 hypothetical protein 956479 3166662 str1061 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141453.1 955991 R 299768 CDS YP_141454.1 55823013 3166199 complement(956614..958191) 1 NC_006449.1 transporter 958191 3166199 str1062 Streptococcus thermophilus CNRZ1066 transporter YP_141454.1 956614 R 299768 CDS YP_141455.1 55823014 3166232 complement(958209..958493) 1 NC_006449.1 hypothetical protein 958493 3166232 str1063 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141455.1 958209 R 299768 CDS YP_141456.1 55823015 3166634 complement(958741..958971) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 958971 3166634 str1064 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141456.1 958741 R 299768 CDS YP_141457.1 55823016 3166170 complement(958968..959213) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 959213 3166170 str1065 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141457.1 958968 R 299768 CDS YP_141458.1 55823017 3166699 complement(959249..959785) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 959785 3166699 str1066 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141458.1 959249 R 299768 CDS YP_141459.1 55823018 3166569 complement(959812..960009) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 960009 3166569 str1067 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141459.1 959812 R 299768 CDS YP_141460.1 55823019 3166690 complement(960253..961389) 1 NC_006449.1 hypothetical protein 961389 3166690 str1068 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141460.1 960253 R 299768 CDS YP_141461.1 55823020 3166197 complement(961468..961983) 1 NC_006449.1 hypothetical protein 961983 3166197 str1069 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141461.1 961468 R 299768 CDS YP_141462.1 55823021 3166849 complement(962079..962474) 1 NC_006449.1 truncated; hypothetical protein 962474 3166849 str1071 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141462.1 962079 R 299768 CDS YP_141463.1 55823022 3166689 complement(962697..963905) 1 NC_006449.1 IS1191 transposase 963905 tnp1191 3166689 tnp1191 Streptococcus thermophilus CNRZ1066 IS1191 transposase YP_141463.1 962697 R 299768 CDS YP_141464.1 55823023 3166297 964293..965369 1 NC_006449.1 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase 965369 epsX 3166297 epsX Streptococcus thermophilus CNRZ1066 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase YP_141464.1 964293 D 299768 CDS YP_141465.1 55823024 3166724 complement(965561..966076) 1 NC_006449.1 truncated; truncated IS1216 transposase 966076 3166724 str1074 Streptococcus thermophilus CNRZ1066 truncated IS1216 transposase YP_141465.1 965561 R 299768 CDS YP_141466.1 55823025 3166586 966412..966987 1 NC_006449.1 hypothetical protein 966987 3166586 str1075 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141466.1 966412 D 299768 CDS YP_141467.1 55823026 3166601 complement(967063..968484) 1 NC_006449.1 exopolysaccharide biosynthesis protein 968484 epsM 3166601 epsM Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141467.1 967063 R 299768 CDS YP_141468.1 55823027 3167492 complement(968492..969415) 1 NC_006449.1 exopolysaccharide polymerization protein 969415 epsL 3167492 epsL Streptococcus thermophilus CNRZ1066 exopolysaccharide polymerization protein YP_141468.1 968492 R 299768 CDS YP_141469.1 55823028 3166589 complement(969375..970325) 1 NC_006449.1 exopolysaccharide gene claster protein 970325 epsK 3166589 epsK Streptococcus thermophilus CNRZ1066 exopolysaccharide gene claster protein YP_141469.1 969375 R 299768 CDS YP_141470.1 55823029 3166867 complement(970350..971432) 1 NC_006449.1 exopolysaccharide polymerization protein 971432 epsJ 3166867 epsJ Streptococcus thermophilus CNRZ1066 exopolysaccharide polymerization protein YP_141470.1 970350 R 299768 CDS YP_141471.1 55823030 3166640 complement(971522..972496) 1 NC_006449.1 exopolysaccharide biosynthesis protein, sugar transferase 972496 epsI 3166640 epsI Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein, sugar transferase YP_141471.1 971522 R 299768 CDS YP_141472.1 55823031 3166311 complement(972502..972972) 1 NC_006449.1 exopolysaccharide biosynthesis protein, acetyltransferase 972972 epsH 3166311 epsH Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein, acetyltransferase YP_141472.1 972502 R 299768 CDS YP_141473.1 55823032 3166684 complement(973174..974316) 1 NC_006449.1 exopolysaccharide biosynthesis protein, glycosyltransferase 974316 epsG 3166684 epsG Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein, glycosyltransferase YP_141473.1 973174 R 299768 CDS YP_141474.1 55823033 3166560 complement(974568..974729) 1 NC_006449.1 truncated; exopolysaccharide biosynthesis protein, UDP-galactopyranose mutase, truncated 974729 3166560 str1083 Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein, UDP-galactopyranose mutase, truncated YP_141474.1 974568 R 299768 CDS YP_141475.1 55823034 3166685 complement(974860..975837) 1 NC_006449.1 exopolysaccharide biosynthesis protein 975837 epsF 3166685 epsF Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141475.1 974860 R 299768 CDS YP_141476.1 55823035 3166398 complement(975983..976666) 1 NC_006449.1 exopolysaccharide biosynthesis protein 976666 epsE 3166398 epsE Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141476.1 975983 R 299768 CDS YP_141477.1 55823036 3166664 complement(976719..977468) 1 NC_006449.1 exopolysaccharide biosynthesis protein 977468 epsD 3166664 epsD Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141477.1 976719 R 299768 CDS YP_141478.1 55823037 3166698 complement(977478..978170) 1 NC_006449.1 exopolysaccharide biosynthesis protein 978170 epsC 3166698 epsC Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141478.1 977478 R 299768 CDS YP_141479.1 55823038 3166416 complement(978179..978910) 1 NC_006449.1 exopolysaccharide biosynthesis protein 978910 epsB 3166416 epsB Streptococcus thermophilus CNRZ1066 exopolysaccharide biosynthesis protein YP_141479.1 978179 R 299768 CDS YP_141480.1 55823039 3166339 complement(978911..980311) 1 NC_006449.1 transcriptional activator-exopolysaccharide biosynthesis 980311 epsA 3166339 epsA Streptococcus thermophilus CNRZ1066 transcriptional activator-exopolysaccharide biosynthesis YP_141480.1 978911 R 299768 CDS YP_141481.1 55823040 3166366 complement(980711..981421) 1 NC_006449.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 981421 deoD 3166366 deoD Streptococcus thermophilus CNRZ1066 purine nucleoside phosphorylase YP_141481.1 980711 R 299768 CDS YP_141482.1 55823041 3166660 complement(981756..982499) 1 NC_006449.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; glutamine amidotransferase 982499 gat 3166660 gat Streptococcus thermophilus CNRZ1066 glutamine amidotransferase YP_141482.1 981756 R 299768 CDS YP_141483.1 55823042 3166675 complement(982830..983234) 1 NC_006449.1 truncated; chloride channel protein, truncated 983234 3166675 str1116 Streptococcus thermophilus CNRZ1066 chloride channel protein, truncated YP_141483.1 982830 R 299768 CDS YP_141484.1 55823043 3166587 complement(983593..984402) 1 NC_006449.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 984402 punA 3166587 punA Streptococcus thermophilus CNRZ1066 purine nucleoside phosphorylase YP_141484.1 983593 R 299768 CDS YP_141485.1 55823044 3166579 complement(984415..984843) 1 NC_006449.1 truncated; hypothetical protein 984843 3166579 str1118 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141485.1 984415 R 299768 CDS YP_141486.1 55823045 3166359 complement(984969..986180) 1 NC_006449.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 986180 deoB 3166359 deoB Streptococcus thermophilus CNRZ1066 phosphopentomutase YP_141486.1 984969 R 299768 CDS YP_141487.1 55823046 3166677 complement(986306..986986) 1 NC_006449.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 986986 rpiA 3166677 rpiA Streptococcus thermophilus CNRZ1066 ribose-5-phosphate isomerase A YP_141487.1 986306 R 299768 CDS YP_141488.1 55823047 3166610 complement(988153..988569) 1 NC_006449.1 hypothetical protein 988569 3166610 str1125 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141488.1 988153 R 299768 CDS YP_141489.1 55823048 3166399 complement(988927..989493) 1 NC_006449.1 hypothetical protein 989493 3166399 str1126 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141489.1 988927 R 299768 CDS YP_141490.1 55823049 3166540 complement(989550..990956) 1 NC_006449.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 990956 pepV 3166540 pepV Streptococcus thermophilus CNRZ1066 dipeptidase PepV YP_141490.1 989550 R 299768 CDS YP_141491.1 55823050 3166305 991187..991372 1 NC_006449.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 991372 xylH 3166305 xylH Streptococcus thermophilus CNRZ1066 4-oxalocrotonate tautomerase YP_141491.1 991187 D 299768 CDS YP_141492.1 55823051 3166184 complement(991448..991921) 1 NC_006449.1 hypothetical protein 991921 3166184 str1129 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141492.1 991448 R 299768 CDS YP_141493.1 55823052 3166637 complement(992076..992249) 1 NC_006449.1 truncated; hypothetical protein 992249 3166637 str1130 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141493.1 992076 R 299768 CDS YP_141494.1 55823053 3166290 complement(992286..992549) 1 NC_006449.1 truncated; hypothetical protein 992549 3166290 str1131 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141494.1 992286 R 299768 CDS YP_141495.1 55823054 3166525 complement(992713..993072) 1 NC_006449.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 993072 rplT 3166525 rplT Streptococcus thermophilus CNRZ1066 50S ribosomal protein L20 YP_141495.1 992713 R 299768 CDS YP_141496.1 55823055 3166532 complement(993129..993329) 1 NC_006449.1 50S ribosomal protein L35 993329 rpmI 3166532 rpmI Streptococcus thermophilus CNRZ1066 50S ribosomal protein L35 YP_141496.1 993129 R 299768 CDS YP_141497.1 55823056 3166585 complement(993368..993898) 1 NC_006449.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 993898 infC 3166585 infC Streptococcus thermophilus CNRZ1066 translation initiation factor IF-3 YP_141497.1 993368 R 299768 CDS YP_141498.1 55823057 3166206 complement(994058..994738) 1 NC_006449.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 994738 cmk 3166206 cmk Streptococcus thermophilus CNRZ1066 cytidylate kinase YP_141498.1 994058 R 299768 CDS YP_141499.1 55823058 3166576 complement(994759..995388) 1 NC_006449.1 hypothetical protein 995388 3166576 str1136 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141499.1 994759 R 299768 CDS YP_141500.1 55823059 3166483 995434..995631 1 NC_006449.1 ferredoxin 995631 fer 3166483 fer Streptococcus thermophilus CNRZ1066 ferredoxin YP_141500.1 995434 D 299768 CDS YP_141501.1 55823060 3166417 complement(995615..996115) 1 NC_006449.1 pore-forming peptide 996115 3166417 str1138 Streptococcus thermophilus CNRZ1066 pore-forming peptide YP_141501.1 995615 R 299768 CDS YP_141502.1 55823061 3166616 complement(996172..997395) 1 NC_006449.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 997395 pepT 3166616 pepT Streptococcus thermophilus CNRZ1066 peptidase T YP_141502.1 996172 R 299768 CDS YP_141503.1 55823062 3166518 complement(997604..998161) 1 NC_006449.1 signal peptidase I 998161 sipB 3166518 sipB Streptococcus thermophilus CNRZ1066 signal peptidase I YP_141503.1 997604 R 299768 CDS YP_141504.1 55823063 3166391 complement(998284..999543) 1 NC_006449.1 hypothetical protein 999543 3166391 str1141 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141504.1 998284 R 299768 CDS YP_141505.1 55823064 3165753 complement(999503..1000681) 1 NC_006449.1 hypothetical protein 1000681 3165753 str1142 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141505.1 999503 R 299768 CDS YP_141506.1 55823065 3166422 complement(1000692..1001174) 1 NC_006449.1 7,8-dihydro-8-oxoguanine-triphosphatase 1001174 mutT 3166422 mutT Streptococcus thermophilus CNRZ1066 7,8-dihydro-8-oxoguanine-triphosphatase YP_141506.1 1000692 R 299768 CDS YP_141507.1 55823066 3165866 complement(1001330..1002295) 1 NC_006449.1 cell division ABC transporter permease 1002295 ftsX 3165866 ftsX Streptococcus thermophilus CNRZ1066 cell division ABC transporter permease YP_141507.1 1001330 R 299768 CDS YP_141508.1 55823067 3166401 complement(1002252..1002959) 1 NC_006449.1 cell division ATP-binding protein 1002959 ftsE 3166401 ftsE Streptococcus thermophilus CNRZ1066 cell division ATP-binding protein YP_141508.1 1002252 R 299768 CDS YP_141509.1 55823068 3166336 complement(1003032..1004045) 1 NC_006449.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1004045 prfB 3166336 prfB Streptococcus thermophilus CNRZ1066 peptide chain release factor 2 YP_141509.1 1003032 R 299768 CDS YP_141510.1 55823070 3166375 complement(1004183..1005301) 1 NC_006449.1 hypothetical protein 1005301 3166375 str1148 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141510.1 1004183 R 299768 CDS YP_141511.1 55823069 3166658 1005314..1006252 1 NC_006449.1 hypothetical protein 1006252 3166658 str1147 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141511.1 1005314 D 299768 CDS YP_141512.1 55823071 3166444 complement(1006276..1007022) 1 NC_006449.1 nitro/flavin reductase 1007022 nfrA 3166444 nfrA Streptococcus thermophilus CNRZ1066 nitro/flavin reductase YP_141512.1 1006276 R 299768 CDS YP_141513.1 55823072 3166445 complement(1007131..1009815) 1 NC_006449.1 calcium transporter P-type ATPase 1009815 pacL2 3166445 pacL2 Streptococcus thermophilus CNRZ1066 calcium transporter P-type ATPase YP_141513.1 1007131 R 299768 CDS YP_141514.1 55823073 3166283 complement(1010081..1010467) 1 NC_006449.1 hypothetical protein 1010467 3166283 str1151 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141514.1 1010081 R 299768 CDS YP_141515.1 55823074 3166443 complement(1010559..1010876) 1 NC_006449.1 truncated; acetyltransferase 1010876 3166443 str1152 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_141515.1 1010559 R 299768 CDS YP_141516.1 55823075 3167344 complement(1011190..1011327) 1 NC_006449.1 truncated; hypothetical protein 1011327 3167344 str1153 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141516.1 1011190 R 299768 CDS YP_141517.1 55823076 3166334 1011647..1012456 1 NC_006449.1 hypothetical protein 1012456 3166334 str1154 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141517.1 1011647 D 299768 CDS YP_141518.1 55823077 3166330 1012458..1013672 1 NC_006449.1 peptidoglycan branched peptide synthesis protein, alanine adding enzyme 1013672 murM 3166330 murM Streptococcus thermophilus CNRZ1066 peptidoglycan branched peptide synthesis protein, alanine adding enzyme YP_141518.1 1012458 D 299768 CDS YP_141519.1 55823078 3166348 complement(1013724..1013837) 1 NC_006449.1 hypothetical protein 1013837 3166348 str1156 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141519.1 1013724 R 299768 CDS YP_141520.1 55823079 3166011 complement(1013837..1014085) 1 NC_006449.1 hypothetical protein 1014085 3166011 str1157 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141520.1 1013837 R 299768 CDS YP_141521.1 55823080 3166388 complement(1014145..1014975) 1 NC_006449.1 hypothetical protein 1014975 vicX 3166388 vicX Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141521.1 1014145 R 299768 CDS YP_141522.1 55823081 3166333 complement(1014963..1016303) 1 NC_006449.1 sensor histidine kinase 1016303 hk05 3166333 hk05 Streptococcus thermophilus CNRZ1066 sensor histidine kinase YP_141522.1 1014963 R 299768 CDS YP_141523.1 55823082 3166347 complement(1016296..1017003) 1 NC_006449.1 response regulator 1017003 rr05 3166347 rr05 Streptococcus thermophilus CNRZ1066 response regulator YP_141523.1 1016296 R 299768 CDS YP_141524.1 55823083 3166318 1017535..1018302 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 1018302 3166318 str1161 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_141524.1 1017535 D 299768 CDS YP_141525.1 55823084 3166442 1018314..1019147 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 1019147 3166442 str1162 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_141525.1 1018314 D 299768 CDS YP_141526.1 55823085 3166931 1019165..1019863 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 1019863 3166931 str1163 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141526.1 1019165 D 299768 CDS YP_141527.1 55823086 3166273 1019875..1020525 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 1020525 3166273 str1164 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141527.1 1019875 D 299768 CDS YP_141528.1 55823087 3166940 complement(1020596..1021477) 1 NC_006449.1 competence associated membrane nuclease 1021477 endA 3166940 endA Streptococcus thermophilus CNRZ1066 competence associated membrane nuclease YP_141528.1 1020596 R 299768 CDS YP_141529.1 55823088 3166906 complement(1021539..1021727) 1 NC_006449.1 competence-associated protein 1021727 epuA 3166906 epuA Streptococcus thermophilus CNRZ1066 competence-associated protein YP_141529.1 1021539 R 299768 CDS YP_141530.1 55823089 3166295 complement(1021729..1023015) 1 NC_006449.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1023015 murA 3166295 murA Streptococcus thermophilus CNRZ1066 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_141530.1 1021729 R 299768 CDS YP_141531.1 55823090 3166271 complement(1023070..1023306) 1 NC_006449.1 hypothetical protein 1023306 3166271 str1168 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141531.1 1023070 R 299768 CDS YP_141532.1 55823091 3166251 complement(1023494..1024507) 1 NC_006449.1 UDP-glucose 4-epimerase 1024507 galE2 3166251 galE2 Streptococcus thermophilus CNRZ1066 UDP-glucose 4-epimerase YP_141532.1 1023494 R 299768 CDS YP_141533.1 55823092 3165667 complement(1024522..1024956) 1 NC_006449.1 hypothetical protein 1024956 3165667 str1170 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141533.1 1024522 R 299768 CDS YP_141534.2 161936369 3166181 complement(1025999..1027192) 1 NC_006449.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1027192 metK 3166181 metK Streptococcus thermophilus CNRZ1066 S-adenosylmethionine synthetase YP_141534.2 1025999 R 299768 CDS YP_141535.1 55823094 3166217 1027473..1028411 1 NC_006449.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1028411 birA 3166217 birA Streptococcus thermophilus CNRZ1066 biotin--protein ligase YP_141535.1 1027473 D 299768 CDS YP_141536.1 55823095 3166140 complement(1028810..1030462) 1 NC_006449.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1030462 dnaX 3166140 dnaX Streptococcus thermophilus CNRZ1066 DNA polymerase III subunits gamma and tau YP_141536.1 1028810 R 299768 CDS YP_141537.1 55823096 3165875 complement(1030462..1030971) 1 NC_006449.1 hypothetical protein 1030971 3165875 str1175 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141537.1 1030462 R 299768 CDS YP_141538.1 55823097 3166150 complement(1031007..1031996) 1 NC_006449.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1031996 miaA 3166150 miaA Streptococcus thermophilus CNRZ1066 tRNA delta(2)-isopentenylpyrophosphate transferase YP_141538.1 1031007 R 299768 CDS YP_141539.1 55823098 3166144 complement(1033103..1033450) 1 NC_006449.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1033450 rplS 3166144 rplS Streptococcus thermophilus CNRZ1066 50S ribosomal protein L19 YP_141539.1 1033103 R 299768 CDS YP_141540.1 55823099 3166591 complement(1033578..1034804) 1 NC_006449.1 hypothetical protein 1034804 3166591 str1180 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141540.1 1033578 R 299768 CDS YP_141541.1 55823100 3166838 complement(1034814..1035086) 1 NC_006449.1 hypothetical protein 1035086 aroH 3166838 aroH Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141541.1 1034814 R 299768 CDS YP_141542.1 55823101 3166125 complement(1035161..1036696) 1 NC_006449.1 chloride channel protein 1036696 3166125 str1182 Streptococcus thermophilus CNRZ1066 chloride channel protein YP_141542.1 1035161 R 299768 CDS YP_141543.1 55823102 3166128 complement(1036747..1037190) 1 NC_006449.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1037190 fld 3166128 fld Streptococcus thermophilus CNRZ1066 flavodoxin YP_141543.1 1036747 R 299768 CDS YP_141544.1 55823103 3166025 complement(1037375..1037647) 1 NC_006449.1 hypothetical protein 1037647 3166025 str1184 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141544.1 1037375 R 299768 CDS YP_141545.1 55823104 3166034 complement(1037659..1038378) 1 NC_006449.1 proteinase 1038378 3166034 str1185 Streptococcus thermophilus CNRZ1066 proteinase YP_141545.1 1037659 R 299768 CDS YP_141546.1 55823105 3166108 complement(1038498..1039280) 1 NC_006449.1 esterase 1039280 estA 3166108 estA Streptococcus thermophilus CNRZ1066 esterase YP_141546.1 1038498 R 299768 CDS YP_141547.1 55823106 3166055 complement(1039405..1041066) 1 NC_006449.1 metallo-beta-lactamase superfamily protein 1041066 3166055 str1187 Streptococcus thermophilus CNRZ1066 metallo-beta-lactamase superfamily protein YP_141547.1 1039405 R 299768 CDS YP_141548.1 55823107 3166019 complement(1041247..1042005) 1 NC_006449.1 ABC transporter ATP binding protein 1042005 3166019 str1188 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141548.1 1041247 R 299768 CDS YP_141549.1 55823108 3166932 complement(1042002..1042871) 1 NC_006449.1 ABC transporter permease 1042871 3166932 str1189 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141549.1 1042002 R 299768 CDS YP_141550.1 55823109 3166214 complement(1042881..1043882) 1 NC_006449.1 ABC transporter substrate binding protein 1043882 3166214 str1190 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein YP_141550.1 1042881 R 299768 CDS YP_141551.1 55823110 3166573 complement(1044019..1044240) 1 NC_006449.1 hypothetical protein 1044240 3166573 str1191 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141551.1 1044019 R 299768 CDS YP_141552.1 55823111 3166600 complement(1044442..1044690) 1 NC_006449.1 hypothetical protein 1044690 3166600 str1192 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141552.1 1044442 R 299768 CDS YP_141553.1 55823112 3166049 complement(1044653..1045132) 1 NC_006449.1 truncated; surface-associated protein cshA precursor, truncated 1045132 3166049 str1193 Streptococcus thermophilus CNRZ1066 surface-associated protein cshA precursor, truncated YP_141553.1 1044653 R 299768 CDS YP_141554.1 55823113 3166057 complement(1045227..1045493) 1 NC_006449.1 hypothetical protein 1045493 3166057 str1194 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141554.1 1045227 R 299768 CDS YP_141555.1 55823114 3166071 complement(1045655..1045894) 1 NC_006449.1 hypothetical protein 1045894 3166071 str1195 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141555.1 1045655 R 299768 CDS YP_141556.2 161936368 3166048 complement(1046786..1048288) 1 NC_006449.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1048288 pyk 3166048 pyk Streptococcus thermophilus CNRZ1066 pyruvate kinase YP_141556.2 1046786 R 299768 CDS YP_141557.1 55823116 3166029 complement(1048358..1049425) 1 NC_006449.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1049425 pfkA 3166029 pfkA Streptococcus thermophilus CNRZ1066 6-phosphofructokinase YP_141557.1 1048358 R 299768 CDS YP_141558.1 55823117 3166076 complement(1049472..1052582) 1 NC_006449.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 1052582 dnaE 3166076 dnaE Streptococcus thermophilus CNRZ1066 DNA polymerase III DnaE YP_141558.1 1049472 R 299768 CDS YP_141559.1 55823118 3166042 complement(1052735..1053520) 1 NC_006449.1 hypothetical protein 1053520 3166042 str1199 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141559.1 1052735 R 299768 CDS YP_141560.1 55823119 3166069 complement(1053617..1054207) 1 NC_006449.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1054207 leuD 3166069 leuD Streptococcus thermophilus CNRZ1066 isopropylmalate isomerase small subunit YP_141560.1 1053617 R 299768 CDS YP_141561.1 55823120 3166033 complement(1054217..1055611) 1 NC_006449.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1055611 leuC 3166033 leuC Streptococcus thermophilus CNRZ1066 isopropylmalate isomerase large subunit YP_141561.1 1054217 R 299768 CDS YP_141562.1 55823121 3166047 complement(1055916..1056962) 1 NC_006449.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1056962 leuB 3166047 leuB Streptococcus thermophilus CNRZ1066 3-isopropylmalate dehydrogenase YP_141562.1 1055916 R 299768 CDS YP_141563.1 55823122 3166008 complement(1056966..1058558) 1 NC_006449.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1058558 leuA 3166008 leuA Streptococcus thermophilus CNRZ1066 2-isopropylmalate synthase YP_141563.1 1056966 R 299768 CDS YP_141564.1 55823123 3166079 complement(1058873..1059565) 1 NC_006449.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1059565 gpmA 3166079 gpmA Streptococcus thermophilus CNRZ1066 phosphoglyceromutase YP_141564.1 1058873 R 299768 CDS YP_141565.1 55823124 3166035 complement(1059706..1060383) 1 NC_006449.1 truncated; truncated IS1239 transposase 1060383 3166035 str1205 Streptococcus thermophilus CNRZ1066 truncated IS1239 transposase YP_141565.1 1059706 R 299768 CDS YP_141566.1 55823125 3165997 complement(1060408..1060701) 1 NC_006449.1 truncated; truncated IS1239 transposase 1060701 3165997 str1206 Streptococcus thermophilus CNRZ1066 truncated IS1239 transposase YP_141566.1 1060408 R 299768 CDS YP_141567.1 55823126 3166010 1061018..1062001 1 NC_006449.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1062001 pyrDa 3166010 pyrDa Streptococcus thermophilus CNRZ1066 dihydroorotate dehydrogenase 1A YP_141567.1 1061018 D 299768 CDS YP_141568.1 55823127 3165993 complement(1062066..1062233) 1 NC_006449.1 hypothetical protein 1062233 3165993 str1208 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141568.1 1062066 R 299768 CDS YP_141569.1 55823128 3166003 complement(1062325..1062600) 1 NC_006449.1 histone-like DNA-binding protein 1062600 hstH 3166003 hstH Streptococcus thermophilus CNRZ1066 histone-like DNA-binding protein YP_141569.1 1062325 R 299768 CDS YP_141570.1 55823129 3165995 complement(1062737..1063306) 1 NC_006449.1 hypothetical protein 1063306 3165995 str1210 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141570.1 1062737 R 299768 CDS YP_141571.1 55823130 3167354 complement(1063299..1064105) 1 NC_006449.1 hypothetical protein 1064105 3167354 str1211 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141571.1 1063299 R 299768 CDS YP_141572.1 55823131 3165923 complement(1064167..1065003) 1 NC_006449.1 hypothetical protein 1065003 3165923 str1212 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141572.1 1064167 R 299768 CDS YP_141573.1 55823132 3165881 complement(1065074..1066744) 1 NC_006449.1 DNA repair and genetic recombination protein 1066744 recN 3165881 recN Streptococcus thermophilus CNRZ1066 DNA repair and genetic recombination protein YP_141573.1 1065074 R 299768 CDS YP_141574.1 55823133 3165914 complement(1066753..1067199) 1 NC_006449.1 transcriptional repressor protein 1067199 3165914 str1214 Streptococcus thermophilus CNRZ1066 transcriptional repressor protein YP_141574.1 1066753 R 299768 CDS YP_141575.1 55823134 3165898 complement(1067147..1068013) 1 NC_006449.1 hemolysin 1068013 3165898 str1215 Streptococcus thermophilus CNRZ1066 hemolysin YP_141575.1 1067147 R 299768 CDS YP_141576.1 55823135 3165905 complement(1068006..1068878) 1 NC_006449.1 geranyltranstransferase, farnesyl diphosphate synthase 1068878 ispA 3165905 ispA Streptococcus thermophilus CNRZ1066 geranyltranstransferase, farnesyl diphosphate synthase YP_141576.1 1068006 R 299768 CDS YP_141577.1 55823136 3166947 complement(1068878..1069093) 1 NC_006449.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1069093 xseB 3166947 xseB Streptococcus thermophilus CNRZ1066 exodeoxyribonuclease VII small subunit YP_141577.1 1068878 R 299768 CDS YP_141578.1 55823137 3165924 complement(1069071..1070411) 1 NC_006449.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1070411 xseA 3165924 xseA Streptococcus thermophilus CNRZ1066 exodeoxyribonuclease VII large subunit YP_141578.1 1069071 R 299768 CDS YP_141579.1 55823138 3165926 complement(1070600..1070845) 1 NC_006449.1 hypothetical protein 1070845 3165926 str1219 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141579.1 1070600 R 299768 CDS YP_141580.1 55823139 3167279 complement(1071478..1072137) 1 NC_006449.1 endonuclease III, DNA repair 1072137 nth 3167279 nth Streptococcus thermophilus CNRZ1066 endonuclease III, DNA repair YP_141580.1 1071478 R 299768 CDS YP_141581.1 55823140 3165743 complement(1072122..1072820) 1 NC_006449.1 DNA replication protein dnaD 1072820 dnaD 3165743 dnaD Streptococcus thermophilus CNRZ1066 DNA replication protein dnaD YP_141581.1 1072122 R 299768 CDS YP_141582.1 55823141 3165919 complement(1072892..1073836) 1 NC_006449.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1073836 metA 3165919 metA Streptococcus thermophilus CNRZ1066 homoserine O-succinyltransferase YP_141582.1 1072892 R 299768 CDS YP_141583.1 55823142 3165880 complement(1074007..1074525) 1 NC_006449.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1074525 apt 3165880 apt Streptococcus thermophilus CNRZ1066 adenine phosphoribosyltransferase YP_141583.1 1074007 R 299768 CDS YP_141584.1 55823143 3167333 complement(1074640..1076850) 1 NC_006449.1 single strand DNA-specific exonuclease 1076850 recJ 3167333 recJ Streptococcus thermophilus CNRZ1066 single strand DNA-specific exonuclease YP_141584.1 1074640 R 299768 CDS YP_141585.1 55823144 3165886 complement(1076863..1077630) 1 NC_006449.1 short chain dehydrogenase/reductase family oxidoreductase 1077630 3165886 str1225 Streptococcus thermophilus CNRZ1066 short chain dehydrogenase/reductase family oxidoreductase YP_141585.1 1076863 R 299768 CDS YP_141586.1 55823145 3165885 complement(1077630..1078559) 1 NC_006449.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1078559 elaC 3165885 elaC Streptococcus thermophilus CNRZ1066 ribonuclease Z YP_141586.1 1077630 R 299768 CDS YP_141587.1 55823146 3165730 complement(1078590..1079231) 1 NC_006449.1 hypothetical protein 1079231 3165730 str1227 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141587.1 1078590 R 299768 CDS YP_141588.1 55823147 3165916 complement(1079224..1080462) 1 NC_006449.1 GTP-binding protein 1080462 hflX 3165916 hflX Streptococcus thermophilus CNRZ1066 GTP-binding protein YP_141588.1 1079224 R 299768 CDS YP_141589.1 55823148 3165841 complement(1080582..1082036) 1 NC_006449.1 cell division protein 1082036 rodA 3165841 rodA Streptococcus thermophilus CNRZ1066 cell division protein YP_141589.1 1080582 R 299768 CDS YP_141590.1 55823149 3165878 complement(1082309..1082725) 1 NC_006449.1 hypothetical protein 1082725 3165878 str1230 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141590.1 1082309 R 299768 CDS YP_141591.1 55823150 3165700 complement(1082822..1083028) 1 NC_006449.1 hypothetical protein 1083028 3165700 str1231 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141591.1 1082822 R 299768 CDS YP_141592.1 55823151 3165908 complement(1083125..1083868) 1 NC_006449.1 hypothetical protein 1083868 hisK 3165908 hisK Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141592.1 1083125 R 299768 CDS YP_141593.1 55823152 3165763 complement(1083868..1084515) 1 NC_006449.1 hypothetical protein 1084515 3165763 str1233 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141593.1 1083868 R 299768 CDS YP_141594.1 55823153 3165792 complement(1084502..1085275) 1 NC_006449.1 N-acetyl-glucosamine catabolism protein 1085275 3165792 str1234 Streptococcus thermophilus CNRZ1066 N-acetyl-glucosamine catabolism protein YP_141594.1 1084502 R 299768 CDS YP_141595.1 55823154 3165723 complement(1085277..1086020) 1 NC_006449.1 acyl-ACP thioesterase 1086020 3165723 str1235 Streptococcus thermophilus CNRZ1066 acyl-ACP thioesterase YP_141595.1 1085277 R 299768 CDS YP_141596.1 55823155 3165833 complement(1086021..1087157) 1 NC_006449.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1087157 hemN 3165833 hemN Streptococcus thermophilus CNRZ1066 coproporphyrinogen III oxidase YP_141596.1 1086021 R 299768 CDS YP_141597.1 55823156 3165733 complement(1087425..1087574) 1 NC_006449.1 hypothetical protein 1087574 3165733 str1237 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141597.1 1087425 R 299768 CDS YP_141598.1 55823157 3165756 1087754..1088008 1 NC_006449.1 hypothetical protein 1088008 3165756 str1238 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141598.1 1087754 D 299768 CDS YP_141599.1 55823158 3167348 complement(1088123..1088446) 1 NC_006449.1 hypothetical protein 1088446 3167348 str1239 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141599.1 1088123 R 299768 CDS YP_141600.1 55823159 3165846 complement(1088625..1088885) 1 NC_006449.1 hypothetical protein 1088885 3165846 str1240 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141600.1 1088625 R 299768 CDS YP_141601.1 55823160 3165716 complement(1088867..1089118) 1 NC_006449.1 hypothetical protein 1089118 3165716 str1241 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141601.1 1088867 R 299768 CDS YP_141602.1 55823161 3165714 complement(1089281..1090327) 1 NC_006449.1 dTDP-glucose-4,6-dehydratase 1090327 rmlB 3165714 rmlB Streptococcus thermophilus CNRZ1066 dTDP-glucose-4,6-dehydratase YP_141602.1 1089281 R 299768 CDS YP_141603.1 55823162 3166552 complement(1090756..1091349) 1 NC_006449.1 dTDP-4-keto-L-rhamnose reductase 1091349 rmlC 3166552 rmlC Streptococcus thermophilus CNRZ1066 dTDP-4-keto-L-rhamnose reductase YP_141603.1 1090756 R 299768 CDS YP_141604.1 55823163 3166873 complement(1091349..1092218) 1 NC_006449.1 glucose-1-phosphate thymidyl transferase 1092218 rmlA 3166873 rmlA Streptococcus thermophilus CNRZ1066 glucose-1-phosphate thymidyl transferase YP_141604.1 1091349 R 299768 CDS YP_141605.1 55823164 3165697 complement(1092450..1093553) 1 NC_006449.1 oxidoreductase, DadA family protein/D-amino acid oxidase 1093553 3165697 str1245 Streptococcus thermophilus CNRZ1066 oxidoreductase, DadA family protein/D-amino acid oxidase YP_141605.1 1092450 R 299768 CDS YP_141606.1 55823165 3167081 complement(1093608..1094276) 1 NC_006449.1 hypothetical protein 1094276 3167081 str1246 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141606.1 1093608 R 299768 CDS YP_141607.1 55823166 3165868 complement(1094449..1095237) 1 NC_006449.1 hypothetical protein 1095237 3165868 str1248 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141607.1 1094449 R 299768 CDS YP_141608.1 55823167 3167493 complement(1095227..1095913) 1 NC_006449.1 hypothetical protein 1095913 3167493 str1249 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141608.1 1095227 R 299768 CDS YP_141609.1 55823168 3165681 complement(1096011..1096451) 1 NC_006449.1 GtrA family protein 1096451 3165681 str1250 Streptococcus thermophilus CNRZ1066 GtrA family protein YP_141609.1 1096011 R 299768 CDS YP_141610.1 55823169 3167200 complement(1096454..1097806) 1 NC_006449.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1097806 glmM 3167200 glmM Streptococcus thermophilus CNRZ1066 phosphoglucosamine mutase YP_141610.1 1096454 R 299768 CDS YP_141611.1 55823170 3166751 complement(1098029..1098994) 1 NC_006449.1 hypothetical protein 1098994 3166751 str1252 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141611.1 1098029 R 299768 CDS YP_141612.1 55823171 3167425 complement(1098991..1099848) 1 NC_006449.1 hypothetical protein 1099848 3167425 str1253 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141612.1 1098991 R 299768 CDS YP_141613.1 55823172 3166886 1099944..1101287 1 NC_006449.1 Mur ligase family protein 1101287 3166886 str1254 Streptococcus thermophilus CNRZ1066 Mur ligase family protein YP_141613.1 1099944 D 299768 CDS YP_141614.1 55823173 3166210 1101287..1102075 1 NC_006449.1 cobyric acid synthase 1102075 cobQ 3166210 cobQ Streptococcus thermophilus CNRZ1066 cobyric acid synthase YP_141614.1 1101287 D 299768 CDS YP_141615.1 55823174 3166086 complement(1102126..1104681) 1 NC_006449.1 hypothetical protein 1104681 3166086 str1256 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141615.1 1102126 R 299768 CDS YP_141616.1 55823175 3165715 complement(1104678..1105397) 1 NC_006449.1 hypothetical protein 1105397 3165715 str1257 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141616.1 1104678 R 299768 CDS YP_141617.1 55823176 3165738 complement(1105512..1105718) 1 NC_006449.1 hypothetical protein 1105718 3165738 str1258 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141617.1 1105512 R 299768 CDS YP_141618.1 55823177 3167471 complement(1105923..1107842) 1 NC_006449.1 ABC transporter ATP binding protein 1107842 3167471 str1259 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141618.1 1105923 R 299768 CDS YP_141619.1 55823178 3166878 complement(1107879..1108514) 1 NC_006449.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1108514 udk 3166878 udk Streptococcus thermophilus CNRZ1066 uridine kinase YP_141619.1 1107879 R 299768 CDS YP_141620.1 55823179 3166889 1108612..1109694 1 NC_006449.1 ATP-dependent RNA helicase 1109694 deaD 3166889 deaD Streptococcus thermophilus CNRZ1066 ATP-dependent RNA helicase YP_141620.1 1108612 D 299768 CDS YP_141621.1 55823180 3166252 complement(1109701..1109853) 1 NC_006449.1 hypothetical protein 1109853 3166252 str1262 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141621.1 1109701 R 299768 CDS YP_141622.1 55823181 3166625 complement(1109983..1111416) 1 NC_006449.1 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1111416 gapN 3166625 gapN Streptococcus thermophilus CNRZ1066 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase YP_141622.1 1109983 R 299768 CDS YP_141623.1 55823182 3166643 complement(1111634..1113367) 1 NC_006449.1 phosphoenolpyruvate:sugar phosphotransferase system enzyme I 1113367 ptsI 3166643 ptsI Streptococcus thermophilus CNRZ1066 phosphoenolpyruvate:sugar phosphotransferase system enzyme I YP_141623.1 1111634 R 299768 CDS YP_141624.1 55823183 3166571 complement(1113372..1113635) 1 NC_006449.1 phosphocarrier protein HPr 1113635 ptsH 3166571 ptsH Streptococcus thermophilus CNRZ1066 phosphocarrier protein HPr YP_141624.1 1113372 R 299768 CDS YP_141625.1 55823184 3166471 complement(1113897..1115072) 1 NC_006449.1 isocitrate dehydrogenase 1115072 icd 3166471 icd Streptococcus thermophilus CNRZ1066 isocitrate dehydrogenase YP_141625.1 1113897 R 299768 CDS YP_141626.1 55823185 3166704 complement(1115087..1116211) 1 NC_006449.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 1116211 gltA 3166704 gltA Streptococcus thermophilus CNRZ1066 citrate synthase YP_141626.1 1115087 R 299768 CDS YP_141627.1 55823186 3166826 complement(1116213..1118876) 1 NC_006449.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1118876 citB 3166826 citB Streptococcus thermophilus CNRZ1066 aconitate hydratase YP_141627.1 1116213 R 299768 CDS YP_141628.1 55823187 3166871 1119207..1119431 1 NC_006449.1 glutaredoxin 1119431 nrdH 3166871 nrdH Streptococcus thermophilus CNRZ1066 glutaredoxin YP_141628.1 1119207 D 299768 CDS YP_141629.1 55823188 3166621 1119518..1121677 1 NC_006449.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1121677 nrdE 3166621 nrdE Streptococcus thermophilus CNRZ1066 ribonucleotide-diphosphate reductase subunit alpha YP_141629.1 1119518 D 299768 CDS YP_141630.1 55823189 3167488 1121836..1122798 1 NC_006449.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1122798 nrdF 3167488 nrdF Streptococcus thermophilus CNRZ1066 ribonucleotide-diphosphate reductase subunit beta YP_141630.1 1121836 D 299768 CDS YP_141631.1 55823190 3166224 1123114..1123320 1 NC_006449.1 truncated; truncated IS1193 transposase 1123320 3166224 str1272 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141631.1 1123114 D 299768 CDS YP_141632.1 55823191 3166721 1123464..1123889 1 NC_006449.1 truncated; hypothetical protein 1123889 3166721 str1273 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141632.1 1123464 D 299768 CDS YP_141633.1 55823192 3165862 1123943..1124329 1 NC_006449.1 truncated; hypothetical protein 1124329 3165862 str1274 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141633.1 1123943 D 299768 CDS YP_141634.1 55823193 3165657 complement(1124594..1125562) 1 NC_006449.1 hypothetical protein 1125562 3165657 str1275 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141634.1 1124594 R 299768 CDS YP_141635.1 55823194 3166298 complement(1125759..1126088) 1 NC_006449.1 hypothetical protein 1126088 3166298 str1276 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141635.1 1125759 R 299768 CDS YP_141636.1 55823195 3166269 complement(1126113..1126490) 1 NC_006449.1 truncated; sortase, truncated 1126490 3166269 str1277 Streptococcus thermophilus CNRZ1066 sortase, truncated YP_141636.1 1126113 R 299768 CDS YP_141637.1 55823196 3167437 complement(1126503..1126874) 1 NC_006449.1 truncated; sortase, truncated 1126874 3167437 str1278 Streptococcus thermophilus CNRZ1066 sortase, truncated YP_141637.1 1126503 R 299768 CDS YP_141638.1 55823197 3165849 complement(1126907..1129342) 1 NC_006449.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1129342 gyrA 3165849 gyrA Streptococcus thermophilus CNRZ1066 DNA gyrase subunit A YP_141638.1 1126907 R 299768 CDS YP_141639.1 55823198 3166636 1129561..1130547 1 NC_006449.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1130547 ldh 3166636 ldh Streptococcus thermophilus CNRZ1066 L-lactate dehydrogenase YP_141639.1 1129561 D 299768 CDS YP_141640.1 55823199 3166821 complement(1130640..1132025) 1 NC_006449.1 NADH oxidase (H2O-forming) 1132025 nox 3166821 nox Streptococcus thermophilus CNRZ1066 NADH oxidase (H2O-forming) YP_141640.1 1130640 R 299768 CDS YP_141641.1 55823200 3166332 complement(1132329..1133867) 1 NC_006449.1 ABC transporter ATP binding protein 1133867 3166332 str1282 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141641.1 1132329 R 299768 CDS YP_141642.1 55823201 3167067 complement(1133938..1134429) 1 NC_006449.1 hypothetical protein 1134429 3167067 str1283 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141642.1 1133938 R 299768 CDS YP_141643.1 55823202 3166818 complement(1134566..1135387) 1 NC_006449.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1135387 pdxK 3166818 pdxK Streptococcus thermophilus CNRZ1066 pyridoxamine kinase YP_141643.1 1134566 R 299768 CDS YP_141644.1 55823203 3166836 complement(1135388..1135897) 1 NC_006449.1 hypothetical protein 1135897 3166836 str1285 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141644.1 1135388 R 299768 CDS YP_141645.1 55823204 3166915 complement(1136035..1136565) 1 NC_006449.1 hypothetical protein 1136565 3166915 str1286 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141645.1 1136035 R 299768 CDS YP_141646.1 55823205 3166822 1136723..1137988 1 NC_006449.1 transcriptional regulator 1137988 3166822 str1287 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141646.1 1136723 D 299768 CDS YP_141647.1 55823206 3166096 complement(1138032..1138370) 1 NC_006449.1 hypothetical protein 1138370 3166096 str1289 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141647.1 1138032 R 299768 CDS YP_141648.1 55823207 3166901 complement(1138461..1138766) 1 NC_006449.1 hypothetical protein 1138766 3166901 str1290 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141648.1 1138461 R 299768 CDS YP_141649.1 55823208 3166213 complement(1138799..1139035) 1 NC_006449.1 hypothetical protein 1139035 3166213 str1291 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141649.1 1138799 R 299768 CDS YP_141650.1 55823209 3166834 complement(1139102..1141552) 1 NC_006449.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1141552 pheT 3166834 pheT Streptococcus thermophilus CNRZ1066 phenylalanyl-tRNA synthetase subunit beta YP_141650.1 1139102 R 299768 CDS YP_141651.1 55823210 3166831 complement(1141811..1142329) 1 NC_006449.1 transcriptional regulator 1142329 3166831 str1293 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_141651.1 1141811 R 299768 CDS YP_141652.2 161936367 3165928 complement(1142346..1143389) 1 NC_006449.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1143389 pheS 3165928 pheS Streptococcus thermophilus CNRZ1066 phenylalanyl-tRNA synthetase subunit alpha YP_141652.2 1142346 R 299768 CDS YP_141653.1 55823212 3165894 complement(1144009..1147542) 1 NC_006449.1 chromosome segregation SMC protein 1147542 smc 3165894 smc Streptococcus thermophilus CNRZ1066 chromosome segregation SMC protein YP_141653.1 1144009 R 299768 CDS YP_141654.1 55823213 3166756 complement(1147545..1148258) 1 NC_006449.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1148258 rnc 3166756 rnc Streptococcus thermophilus CNRZ1066 ribonuclease III YP_141654.1 1147545 R 299768 CDS YP_141655.1 55823214 3166299 complement(1148389..1149360) 1 NC_006449.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1149360 dapA 3166299 dapA Streptococcus thermophilus CNRZ1066 dihydrodipicolinate synthase YP_141655.1 1148389 R 299768 CDS YP_141656.1 55823215 3166656 complement(1149663..1150739) 1 NC_006449.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1150739 asd 3166656 asd Streptococcus thermophilus CNRZ1066 aspartate-semialdehyde dehydrogenase YP_141656.1 1149663 R 299768 CDS YP_141657.1 55823216 3166891 complement(1151029..1151508) 1 NC_006449.1 DNA alkylation repair protein 1151508 alkD 3166891 alkD Streptococcus thermophilus CNRZ1066 DNA alkylation repair protein YP_141657.1 1151029 R 299768 CDS YP_141658.1 55823217 3166757 complement(1151868..1152449) 1 NC_006449.1 phosphinothricin acetyltransferase 1152449 3166757 str1301 Streptococcus thermophilus CNRZ1066 phosphinothricin acetyltransferase YP_141658.1 1151868 R 299768 CDS YP_141659.1 55823218 3166854 1152673..1152879 1 NC_006449.1 truncated; truncated IS1193 transposase 1152879 3166854 str1302 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141659.1 1152673 D 299768 CDS YP_141660.1 55823219 3167349 1152967..1153392 1 NC_006449.1 truncated; truncated IS1193 transposase 1153392 3167349 str1304 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141660.1 1152967 D 299768 CDS YP_141661.1 55823220 3166609 complement(1153431..1154882) 1 NC_006449.1 cardiolipin synthetase 1154882 cls 3166609 cls Streptococcus thermophilus CNRZ1066 cardiolipin synthetase YP_141661.1 1153431 R 299768 CDS YP_141662.1 55823221 3166667 complement(1155070..1156857) 1 NC_006449.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1156857 uvrC 3166667 uvrC Streptococcus thermophilus CNRZ1066 excinuclease ABC subunit C YP_141662.1 1155070 R 299768 CDS YP_141663.1 55823222 3166727 complement(1156917..1157612) 1 NC_006449.1 HAD superfamily hydrolase 1157612 3166727 str1307 Streptococcus thermophilus CNRZ1066 HAD superfamily hydrolase YP_141663.1 1156917 R 299768 CDS YP_141664.1 55823223 3166044 1157940..1158374 1 NC_006449.1 biotin synthase 1158374 bioY2 3166044 bioY2 Streptococcus thermophilus CNRZ1066 biotin synthase YP_141664.1 1157940 D 299768 CDS YP_141665.1 55823224 3166928 complement(1158609..1159298) 1 NC_006449.1 proline/glycine betaine ABC transporter 1159298 proWX 3166928 proWX Streptococcus thermophilus CNRZ1066 proline/glycine betaine ABC transporter YP_141665.1 1158609 R 299768 CDS YP_141666.1 55823225 3167383 complement(1159240..1159995) 1 NC_006449.1 proline/glycine betaine ABC transporter ATP-binding protein 1159995 proV 3167383 proV Streptococcus thermophilus CNRZ1066 proline/glycine betaine ABC transporter ATP-binding protein YP_141666.1 1159240 R 299768 CDS YP_141667.1 55823226 3166158 complement(1160007..1160924) 1 NC_006449.1 proline/glycine betaine ABC transporter membrane-spanning protein 1160924 proWY 3166158 proWY Streptococcus thermophilus CNRZ1066 proline/glycine betaine ABC transporter membrane-spanning protein YP_141667.1 1160007 R 299768 CDS YP_141668.1 55823227 3167386 complement(1160921..1161580) 1 NC_006449.1 proline/glycine betaine ABC transporter substrate-binding protein 1161580 proWZ 3167386 proWZ Streptococcus thermophilus CNRZ1066 proline/glycine betaine ABC transporter substrate-binding protein YP_141668.1 1160921 R 299768 CDS YP_141669.1 55823228 3166670 complement(1161637..1163133) 1 NC_006449.1 histidine ammonia-lyase 1163133 hutH 3166670 hutH Streptococcus thermophilus CNRZ1066 histidine ammonia-lyase YP_141669.1 1161637 R 299768 CDS YP_141670.1 55823229 3166735 complement(1163156..1164259) 1 NC_006449.1 hypothetical protein 1164259 3166735 str1314 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141670.1 1163156 R 299768 CDS YP_141671.1 55823230 3166896 complement(1164276..1165910) 1 NC_006449.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1165910 hutU 3166896 hutU Streptococcus thermophilus CNRZ1066 urocanate hydratase YP_141671.1 1164276 R 299768 CDS YP_141672.1 55823231 3166335 1166349..1167062 1 NC_006449.1 L-serine dehydratase subunit beta 1167062 sdaB 3166335 sdaB Streptococcus thermophilus CNRZ1066 L-serine dehydratase subunit beta YP_141672.1 1166349 D 299768 CDS YP_141673.1 55823232 3167220 1167075..1167944 1 NC_006449.1 L-serine dehydratase subunit alpha 1167944 sdaA 3167220 sdaA Streptococcus thermophilus CNRZ1066 L-serine dehydratase subunit alpha YP_141673.1 1167075 D 299768 CDS YP_141674.1 55823233 3166910 complement(1168667..1169236) 1 NC_006449.1 hypothetical protein 1169236 3166910 str1318 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141674.1 1168667 R 299768 CDS YP_141675.1 55823234 3167350 complement(1169372..1170163) 1 NC_006449.1 ABC transporter permease 1170163 3167350 str1319 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141675.1 1169372 R 299768 CDS YP_141676.1 55823235 3166890 complement(1170160..1170441) 1 NC_006449.1 truncated; hypothetical protein 1170441 3166890 str1320 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141676.1 1170160 R 299768 CDS YP_141677.1 55823236 3166924 complement(1170411..1170983) 1 NC_006449.1 truncated; hypothetical protein 1170983 3166924 str1321 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141677.1 1170411 R 299768 CDS YP_141678.1 55823237 3166374 complement(1171169..1171399) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1171399 3166374 str1322 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_141678.1 1171169 R 299768 CDS YP_141679.1 55823238 3166903 complement(1171548..1171802) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1171802 3166903 str1323 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_141679.1 1171548 R 299768 CDS YP_141680.1 55823239 3165638 complement(1171829..1171936) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1171936 3165638 str1324 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_141680.1 1171829 R 299768 CDS YP_141681.1 55823240 3166186 complement(1172344..1172946) 1 NC_006449.1 response regulator 1172946 rr06 3166186 rr06 Streptococcus thermophilus CNRZ1066 response regulator YP_141681.1 1172344 R 299768 CDS YP_141682.1 55823241 3166040 complement(1172943..1174043) 1 NC_006449.1 sensor histidine kinase 1174043 hk06 3166040 hk06 Streptococcus thermophilus CNRZ1066 sensor histidine kinase YP_141682.1 1172943 R 299768 CDS YP_141683.1 55823242 3167486 complement(1174030..1174767) 1 NC_006449.1 ABC transporter permease 1174767 3167486 str1327 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141683.1 1174030 R 299768 CDS YP_141684.1 55823243 3167278 complement(1174764..1175645) 1 NC_006449.1 ABC transporter ATP binding protein 1175645 3167278 str1328 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141684.1 1174764 R 299768 CDS YP_141685.1 55823244 3167490 complement(1175828..1176037) 1 NC_006449.1 hypothetical protein 1176037 3167490 str1329 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141685.1 1175828 R 299768 CDS YP_141686.1 55823245 3166242 complement(1176189..1177127) 1 NC_006449.1 Na+-dependent transporter 1177127 3166242 str1330 Streptococcus thermophilus CNRZ1066 Na+-dependent transporter YP_141686.1 1176189 R 299768 CDS YP_141687.1 55823246 3166190 complement(1177272..1177721) 1 NC_006449.1 cytidine/deoxycytidylate deaminase family protein 1177721 3166190 str1331 Streptococcus thermophilus CNRZ1066 cytidine/deoxycytidylate deaminase family protein YP_141687.1 1177272 R 299768 CDS YP_141688.1 55823247 3167190 complement(1177889..1178110) 1 NC_006449.1 hypothetical protein 1178110 3167190 str1332 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141688.1 1177889 R 299768 CDS YP_141689.1 55823248 3167228 complement(1178195..1180195) 1 NC_006449.1 ABC transporter permease/substrate binding protein 1180195 3167228 str1333 Streptococcus thermophilus CNRZ1066 ABC transporter permease/substrate binding protein YP_141689.1 1178195 R 299768 CDS YP_141690.1 55823249 3167257 complement(1180197..1180955) 1 NC_006449.1 ABC transporter ATP binding protein 1180955 3167257 str1334 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141690.1 1180197 R 299768 CDS YP_141691.1 55823250 3167217 complement(1181099..1182073) 1 NC_006449.1 sensor histidine kinase 1182073 hk07 3167217 hk07 Streptococcus thermophilus CNRZ1066 sensor histidine kinase YP_141691.1 1181099 R 299768 CDS YP_141692.1 55823251 3166875 complement(1182063..1182743) 1 NC_006449.1 response regulator 1182743 rr07 3166875 rr07 Streptococcus thermophilus CNRZ1066 response regulator YP_141692.1 1182063 R 299768 CDS YP_141693.1 55823252 3167255 1183295..1183735 1 NC_006449.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1183735 xpt 3167255 xpt Streptococcus thermophilus CNRZ1066 xanthine phosphoribosyltransferase YP_141693.1 1183295 D 299768 CDS YP_141694.1 55823253 3166194 1183735..1184295 1 NC_006449.1 truncated; nucleobase:cation symporter for xanthine, truncated 1184295 3166194 str1339 Streptococcus thermophilus CNRZ1066 nucleobase:cation symporter for xanthine, truncated YP_141694.1 1183735 D 299768 CDS YP_141695.1 55823254 3167222 1184175..1184762 1 NC_006449.1 truncated; nucleobase:cation symporter for xanthine, truncated 1184762 3167222 str1340 Streptococcus thermophilus CNRZ1066 nucleobase:cation symporter for xanthine, truncated YP_141695.1 1184175 D 299768 CDS YP_141696.1 55823255 3165701 1184756..1185007 1 NC_006449.1 truncated; nucleobase:cation symporter for xanthine, truncated 1185007 3165701 str1341 Streptococcus thermophilus CNRZ1066 nucleobase:cation symporter for xanthine, truncated YP_141696.1 1184756 D 299768 CDS YP_141697.1 55823256 3167282 1185135..1186484 1 NC_006449.1 MATE efflux family Na(+)/drug antiporter 1186484 norM 3167282 norM Streptococcus thermophilus CNRZ1066 MATE efflux family Na(+)/drug antiporter YP_141697.1 1185135 D 299768 CDS YP_141698.1 55823257 3166930 complement(1186849..1187871) 1 NC_006449.1 this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 1187871 msrA1 3166930 msrA1 Streptococcus thermophilus CNRZ1066 bifunctional methionine sulfoxide reductase A/B protein YP_141698.1 1186849 R 299768 CDS YP_141699.1 55823258 3165649 complement(1187927..1188739) 1 NC_006449.1 ABC transporter substrate binding protein 1188739 3165649 str1344 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein YP_141699.1 1187927 R 299768 CDS YP_141700.1 55823259 3166061 complement(1188758..1190107) 1 NC_006449.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1190107 purB2 3166061 purB2 Streptococcus thermophilus CNRZ1066 adenylosuccinate lyase YP_141700.1 1188758 R 299768 CDS YP_141701.1 55823260 3166216 complement(1190117..1190884) 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 1190884 3166216 str1346 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_141701.1 1190117 R 299768 CDS YP_141702.1 55823261 3166355 complement(1190871..1191566) 1 NC_006449.1 ABC transporter amino acid permease 1191566 3166355 str1347 Streptococcus thermophilus CNRZ1066 ABC transporter amino acid permease YP_141702.1 1190871 R 299768 CDS YP_141703.1 55823262 3165899 complement(1191550..1192095) 1 NC_006449.1 hypothetical protein 1192095 3165899 str1348 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141703.1 1191550 R 299768 CDS YP_141704.1 55823263 3166883 complement(1192099..1193412) 1 NC_006449.1 hypothetical protein 1193412 3166883 str1349 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141704.1 1192099 R 299768 CDS YP_141705.1 55823264 3167285 complement(1193409..1194179) 1 NC_006449.1 truncated; aspartate aminotransferase, truncated 1194179 3167285 str1350 Streptococcus thermophilus CNRZ1066 aspartate aminotransferase, truncated YP_141705.1 1193409 R 299768 CDS YP_141706.1 55823265 3165858 complement(1194221..1194559) 1 NC_006449.1 truncated; aspartate aminotransferase, truncated 1194559 3165858 str1351 Streptococcus thermophilus CNRZ1066 aspartate aminotransferase, truncated YP_141706.1 1194221 R 299768 CDS YP_141707.1 55823266 3167540 complement(1194586..1194930) 1 NC_006449.1 truncated; glycerol dehydrogenase, truncated 1194930 3167540 str1352 Streptococcus thermophilus CNRZ1066 glycerol dehydrogenase, truncated YP_141707.1 1194586 R 299768 CDS YP_141708.1 55823267 3167372 complement(1195003..1195452) 1 NC_006449.1 truncated; glycerol dehydrogenase, truncated 1195452 3167372 str1353 Streptococcus thermophilus CNRZ1066 glycerol dehydrogenase, truncated YP_141708.1 1195003 R 299768 CDS YP_141709.1 55823268 3166219 complement(1195640..1196827) 1 NC_006449.1 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 1196827 hipO2 3166219 hipO2 Streptococcus thermophilus CNRZ1066 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_141709.1 1195640 R 299768 CDS YP_141710.1 55823269 3167543 complement(1197061..1198389) 1 NC_006449.1 branched chain amino acid transport system II carrier protein 1198389 brnQ 3167543 brnQ Streptococcus thermophilus CNRZ1066 branched chain amino acid transport system II carrier protein YP_141710.1 1197061 R 299768 CDS YP_141711.1 55823270 3166813 complement(1198603..1198989) 1 NC_006449.1 truncated; mannose-6-phosphate isomerase 1198989 3166813 str1358 Streptococcus thermophilus CNRZ1066 mannose-6-phosphate isomerase YP_141711.1 1198603 R 299768 CDS YP_141712.1 55823271 3166885 complement(1198964..1199287) 1 NC_006449.1 truncated; mannose-6-phosphate isomerase 1199287 3166885 str1359 Streptococcus thermophilus CNRZ1066 mannose-6-phosphate isomerase YP_141712.1 1198964 R 299768 CDS YP_141713.1 55823272 3167541 1199448..1199642 1 NC_006449.1 hypothetical protein 1199642 3167541 str1360 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141713.1 1199448 D 299768 CDS YP_141714.1 55823273 3167375 complement(1200513..1201898) 1 NC_006449.1 amino acid transporter 1201898 3167375 str1361 Streptococcus thermophilus CNRZ1066 amino acid transporter YP_141714.1 1200513 R 299768 CDS YP_141715.1 55823274 3166361 complement(1201962..1202228) 1 NC_006449.1 hypothetical protein 1202228 3166361 str1362 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141715.1 1201962 R 299768 CDS YP_141716.1 55823275 3165838 complement(1202324..1202926) 1 NC_006449.1 hypothetical protein 1202926 3165838 str1363 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141716.1 1202324 R 299768 CDS YP_141717.1 55823276 3167544 complement(1203105..1203230) 1 NC_006449.1 truncated; hypothetical protein 1203230 3167544 str1364 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141717.1 1203105 R 299768 CDS YP_141718.1 55823277 3166078 complement(1203378..1203884) 1 NC_006449.1 truncated; hypothetical protein 1203884 3166078 str1365 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141718.1 1203378 R 299768 CDS YP_141719.1 55823278 3165840 complement(1204052..1204501) 1 NC_006449.1 Rrf2 family protein 1204501 3165840 str1366 Streptococcus thermophilus CNRZ1066 Rrf2 family protein YP_141719.1 1204052 R 299768 CDS YP_141720.1 55823279 3166556 complement(1204683..1205546) 1 NC_006449.1 hypothetical protein 1205546 3166556 str1367 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141720.1 1204683 R 299768 CDS YP_141721.1 55823280 3166630 complement(1205533..1206825) 1 NC_006449.1 PTS system cellobiose-specific IIC component 1206825 celB 3166630 celB Streptococcus thermophilus CNRZ1066 PTS system cellobiose-specific IIC component YP_141721.1 1205533 R 299768 CDS YP_141722.1 55823281 3166644 complement(1207013..1207666) 1 NC_006449.1 NAD(P)H nitroreductase 1207666 3166644 str1369 Streptococcus thermophilus CNRZ1066 NAD(P)H nitroreductase YP_141722.1 1207013 R 299768 CDS YP_141723.1 55823282 3167268 complement(1207738..1208334) 1 NC_006449.1 hypothetical protein 1208334 3167268 str1370 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141723.1 1207738 R 299768 CDS YP_141724.1 55823283 3167143 complement(1208490..1209392) 1 NC_006449.1 aldo/keto reductase 1209392 3167143 str1371 Streptococcus thermophilus CNRZ1066 aldo/keto reductase YP_141724.1 1208490 R 299768 CDS YP_141725.1 55823284 3167360 complement(1209504..1209596) 1 NC_006449.1 truncated; UDP-glucose 4-epimerase, truncated 1209596 3167360 str1372 Streptococcus thermophilus CNRZ1066 UDP-glucose 4-epimerase, truncated YP_141725.1 1209504 R 299768 CDS YP_141726.1 55823285 3166432 complement(1209705..1210022) 1 NC_006449.1 truncated; UDP-glucose 4-epimerase, truncated 1210022 3166432 str1373 Streptococcus thermophilus CNRZ1066 UDP-glucose 4-epimerase, truncated YP_141726.1 1209705 R 299768 CDS YP_141727.1 55823286 3167451 complement(1210331..1211011) 1 NC_006449.1 hypothetical protein 1211011 3167451 str1374 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141727.1 1210331 R 299768 CDS YP_141728.1 55823287 3167288 complement(1211110..1215480) 1 NC_006449.1 type II restriction-modification system restriction subunit 1215480 sthII 3167288 sthII Streptococcus thermophilus CNRZ1066 type II restriction-modification system restriction subunit YP_141728.1 1211110 R 299768 CDS YP_141729.1 55823288 3167459 complement(1215487..1216161) 1 NC_006449.1 type II restriction-modification system modification subunit 1216161 llaBIIM 3167459 llaBIIM Streptococcus thermophilus CNRZ1066 type II restriction-modification system modification subunit YP_141729.1 1215487 R 299768 CDS YP_141730.1 55823289 3166499 1216422..1217906 1 NC_006449.1 hypothetical protein 1217906 3166499 str1377 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141730.1 1216422 D 299768 CDS YP_141731.1 55823290 3166882 complement(1218126..1218470) 1 NC_006449.1 hypothetical protein 1218470 3166882 str1378 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141731.1 1218126 R 299768 CDS YP_141732.1 55823291 3167430 1218730..1218993 1 NC_006449.1 hypothetical protein 1218993 3167430 str1379 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141732.1 1218730 D 299768 CDS YP_141733.1 55823292 3167469 complement(1219242..1219382) 1 NC_006449.1 truncated; response regulator 1219382 3167469 str1380 Streptococcus thermophilus CNRZ1066 response regulator YP_141733.1 1219242 R 299768 CDS YP_141734.1 55823293 3167442 complement(1219500..1219862) 1 NC_006449.1 truncated; response regulator 1219862 3167442 str1381 Streptococcus thermophilus CNRZ1066 response regulator YP_141734.1 1219500 R 299768 CDS YP_141735.1 55823294 3167484 complement(1219942..1220397) 1 NC_006449.1 cell wall surface anchor family protein 1220397 3167484 str1382 Streptococcus thermophilus CNRZ1066 cell wall surface anchor family protein YP_141735.1 1219942 R 299768 CDS YP_141736.1 55823295 3167423 1220435..1220653 1 NC_006449.1 hypothetical protein 1220653 3167423 str1383 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141736.1 1220435 D 299768 CDS YP_141737.1 55823296 3166862 complement(1220699..1221058) 1 NC_006449.1 hypothetical protein 1221058 3166862 str1384 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141737.1 1220699 R 299768 CDS YP_141738.1 55823297 3166498 complement(1221055..1222470) 1 NC_006449.1 SOS responce UmuC protein 1222470 umuC1 3166498 umuC1 Streptococcus thermophilus CNRZ1066 SOS responce UmuC protein YP_141738.1 1221055 R 299768 CDS YP_141739.1 55823298 3167447 complement(1222643..1223680) 1 NC_006449.1 hypothetical protein 1223680 3167447 str1386 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141739.1 1222643 R 299768 CDS YP_141740.1 55823299 3167405 1223919..1224206 1 NC_006449.1 hypothetical protein 1224206 3167405 str1387 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141740.1 1223919 D 299768 CDS YP_141741.1 55823300 3167452 1224455..1224703 1 NC_006449.1 hypothetical protein 1224703 3167452 str1388 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141741.1 1224455 D 299768 CDS YP_141742.1 55823301 3167409 1224914..1225531 1 NC_006449.1 amino-acid efflux protein 1225531 3167409 str1389 Streptococcus thermophilus CNRZ1066 amino-acid efflux protein YP_141742.1 1224914 D 299768 CDS YP_141743.1 55823302 3167406 complement(1225872..1226231) 1 NC_006449.1 hypothetical protein 1226231 3167406 str1391 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141743.1 1225872 R 299768 CDS YP_141744.1 55823303 3166934 complement(1226789..1228882) 1 NC_006449.1 glycosyl transferase 1228882 3166934 str1392 Streptococcus thermophilus CNRZ1066 glycosyl transferase YP_141744.1 1226789 R 299768 CDS YP_141745.1 55823304 3167458 1229460..1229795 1 NC_006449.1 hypothetical protein 1229795 3167458 str1393 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141745.1 1229460 D 299768 CDS YP_141746.1 55823305 3167456 complement(1230216..1233395) 1 NC_006449.1 ATP-dependent dsDNA exonuclease 1233395 sbcC 3167456 sbcC Streptococcus thermophilus CNRZ1066 ATP-dependent dsDNA exonuclease YP_141746.1 1230216 R 299768 CDS YP_141747.1 55823306 3167110 complement(1233392..1234618) 1 NC_006449.1 ATP-dependent dsDNA exonuclease 1234618 sbcD 3167110 sbcD Streptococcus thermophilus CNRZ1066 ATP-dependent dsDNA exonuclease YP_141747.1 1233392 R 299768 CDS YP_141748.1 55823307 3167468 complement(1234697..1234873) 1 NC_006449.1 truncated; hypothetical protein 1234873 3167468 str1396 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141748.1 1234697 R 299768 CDS YP_141749.1 55823308 3167420 complement(1235455..1238535) 1 NC_006449.1 beta-galactosidase 1238535 lacZ 3167420 lacZ Streptococcus thermophilus CNRZ1066 beta-galactosidase YP_141749.1 1235455 R 299768 CDS YP_141750.1 55823309 3167417 complement(1238539..1240443) 1 NC_006449.1 sodium:beta-glucoside symporter 1240443 lacS 3167417 lacS Streptococcus thermophilus CNRZ1066 sodium:beta-glucoside symporter YP_141750.1 1238539 R 299768 CDS YP_141751.1 55823310 3167444 complement(1240546..1241592) 1 NC_006449.1 aldose 1-epimerase 1241592 galM 3167444 galM Streptococcus thermophilus CNRZ1066 aldose 1-epimerase YP_141751.1 1240546 R 299768 CDS YP_141752.1 55823311 3167435 complement(1241662..1242663) 1 NC_006449.1 UDP-glucose 4-epimerase 1242663 galE1 3167435 galE1 Streptococcus thermophilus CNRZ1066 UDP-glucose 4-epimerase YP_141752.1 1241662 R 299768 CDS YP_141753.1 55823312 3167466 complement(1242693..1244201) 1 NC_006449.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1244201 galT 3167466 galT Streptococcus thermophilus CNRZ1066 galactose-1-phosphate uridylyltransferase YP_141753.1 1242693 R 299768 CDS YP_141754.1 55823313 3167453 complement(1244194..1245360) 1 NC_006449.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1245360 galK 3167453 galK Streptococcus thermophilus CNRZ1066 galactokinase YP_141754.1 1244194 R 299768 CDS YP_141755.1 55823314 3167398 1245503..1246498 1 NC_006449.1 galactose operon repressor 1246498 galR 3167398 galR Streptococcus thermophilus CNRZ1066 galactose operon repressor YP_141755.1 1245503 D 299768 CDS YP_141756.1 55823315 3167431 complement(1247080..1247280) 1 NC_006449.1 truncated; hypothetical protein 1247280 3167431 str1404 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141756.1 1247080 R 299768 CDS YP_141757.1 55823316 3167476 complement(1247293..1247481) 1 NC_006449.1 truncated; hypothetical protein 1247481 3167476 str1405 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141757.1 1247293 R 299768 CDS YP_141758.1 55823317 3167436 complement(1247654..1248745) 1 NC_006449.1 truncated; zinc metalloprotease ZmpB, truncated 1248745 3167436 str1406 Streptococcus thermophilus CNRZ1066 zinc metalloprotease ZmpB, truncated YP_141758.1 1247654 R 299768 CDS YP_141759.1 55823318 3167464 complement(1248708..1249148) 1 NC_006449.1 truncated; zinc metalloprotease ZmpB, truncated 1249148 3167464 str1407 Streptococcus thermophilus CNRZ1066 zinc metalloprotease ZmpB, truncated YP_141759.1 1248708 R 299768 CDS YP_141760.1 55823319 3167450 complement(1249179..1249277) 1 NC_006449.1 truncated; zinc metalloprotease ZmpB, truncated 1249277 3167450 str1408 Streptococcus thermophilus CNRZ1066 zinc metalloprotease ZmpB, truncated YP_141760.1 1249179 R 299768 CDS YP_141761.1 55823320 3166478 1249644..1249904 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1249904 3166478 str1409 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_141761.1 1249644 D 299768 CDS YP_141762.1 55823321 3167483 complement(1249959..1250060) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1250060 3167483 str1410 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_141762.1 1249959 R 299768 CDS YP_141763.1 55823322 3167454 complement(1250091..1250657) 1 NC_006449.1 truncated; ABC transporter truncated 1250657 3167454 str1411 Streptococcus thermophilus CNRZ1066 ABC transporter truncated YP_141763.1 1250091 R 299768 CDS YP_141764.1 55823323 3167467 complement(1250543..1250815) 1 NC_006449.1 truncated; ABC transporter truncated 1250815 3167467 str1412 Streptococcus thermophilus CNRZ1066 ABC transporter truncated YP_141764.1 1250543 R 299768 CDS YP_141765.1 55823324 3167482 1251499..1253763 1 NC_006449.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1253763 3167482 str1413 Streptococcus thermophilus CNRZ1066 bifunctional glutamate--cysteine ligase/glutathione synthetase YP_141765.1 1251499 D 299768 CDS YP_141766.1 55823325 3167440 1253820..1254485 1 NC_006449.1 truncated; truncated IS1193 transposase 1254485 3167440 str1414 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141766.1 1253820 D 299768 CDS YP_141767.1 55823326 3167426 1254783..1254953 1 NC_006449.1 truncated; truncated IS1193 transposase 1254953 3167426 str1415 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_141767.1 1254783 D 299768 CDS YP_141768.1 55823327 3167432 complement(1255072..1257486) 1 NC_006449.1 cell division protein 1257486 ftsK 3167432 ftsK Streptococcus thermophilus CNRZ1066 cell division protein YP_141768.1 1255072 R 299768 CDS YP_141769.1 55823328 3167403 complement(1257639..1258637) 1 NC_006449.1 thioredoxin reductase 1258637 trxB2 3167403 trxB2 Streptococcus thermophilus CNRZ1066 thioredoxin reductase YP_141769.1 1257639 R 299768 CDS YP_141770.1 55823329 3167416 complement(1258639..1259358) 1 NC_006449.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1259358 trmD 3167416 trmD Streptococcus thermophilus CNRZ1066 tRNA (guanine-N(1)-)-methyltransferase YP_141770.1 1258639 R 299768 CDS YP_141771.1 55823330 3167473 complement(1259348..1259866) 1 NC_006449.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1259866 rimM 3167473 rimM Streptococcus thermophilus CNRZ1066 16S rRNA-processing protein RimM YP_141771.1 1259348 R 299768 CDS YP_141772.1 55823331 3167413 complement(1260538..1261182) 1 NC_006449.1 response regulator 1261182 rr08 3167413 rr08 Streptococcus thermophilus CNRZ1066 response regulator YP_141772.1 1260538 R 299768 CDS YP_141773.1 55823332 3167462 complement(1261172..1262182) 1 NC_006449.1 sensor histidine kinase 1262182 hk08 3167462 hk08 Streptococcus thermophilus CNRZ1066 sensor histidine kinase YP_141773.1 1261172 R 299768 CDS YP_141774.1 55823333 3167438 complement(1262179..1262877) 1 NC_006449.1 transporter 1262877 3167438 str1422 Streptococcus thermophilus CNRZ1066 transporter YP_141774.1 1262179 R 299768 CDS YP_141775.1 55823334 3167475 complement(1263143..1263298) 1 NC_006449.1 truncated; potassium channel protein, truncated 1263298 3167475 str1423 Streptococcus thermophilus CNRZ1066 potassium channel protein, truncated YP_141775.1 1263143 R 299768 CDS YP_141776.1 55823335 3167479 complement(1263530..1263682) 1 NC_006449.1 truncated; potassium channel protein, truncated 1263682 3167479 str1424 Streptococcus thermophilus CNRZ1066 potassium channel protein, truncated YP_141776.1 1263530 R 299768 CDS YP_141777.1 55823336 3167449 complement(1263935..1265806) 1 NC_006449.1 protein kinase 1265806 pknB 3167449 pknB Streptococcus thermophilus CNRZ1066 protein kinase YP_141777.1 1263935 R 299768 CDS YP_141778.1 55823337 3166157 complement(1265806..1266624) 1 NC_006449.1 phosphoprotein phosphatase 1266624 pppL 3166157 pppL Streptococcus thermophilus CNRZ1066 phosphoprotein phosphatase YP_141778.1 1265806 R 299768 CDS YP_141779.1 55823338 3167419 complement(1266587..1267918) 1 NC_006449.1 RNA-binding protein 1267918 sunL 3167419 sunL Streptococcus thermophilus CNRZ1066 RNA-binding protein YP_141779.1 1266587 R 299768 CDS YP_141780.1 55823339 3167446 complement(1267899..1268834) 1 NC_006449.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1268834 fmt 3167446 fmt Streptococcus thermophilus CNRZ1066 methionyl-tRNA formyltransferase YP_141780.1 1267899 R 299768 CDS YP_141781.1 55823340 3167477 complement(1268852..1271248) 1 NC_006449.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1271248 priA 3167477 priA Streptococcus thermophilus CNRZ1066 primosome assembly protein PriA YP_141781.1 1268852 R 299768 CDS YP_141782.1 55823341 3167480 complement(1271390..1271704) 1 NC_006449.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1271704 rpoZ 3167480 rpoZ Streptococcus thermophilus CNRZ1066 DNA-directed RNA polymerase subunit omega YP_141782.1 1271390 R 299768 CDS YP_141783.1 55823342 3167461 complement(1271726..1272355) 1 NC_006449.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1272355 gmk 3167461 gmk Streptococcus thermophilus CNRZ1066 guanylate kinase YP_141783.1 1271726 R 299768 CDS YP_141784.1 55823343 3166809 complement(1272588..1273979) 1 NC_006449.1 signal recognition particle receptor 1273979 ftsY 3166809 ftsY Streptococcus thermophilus CNRZ1066 signal recognition particle receptor YP_141784.1 1272588 R 299768 CDS YP_141785.1 55823344 3167463 complement(1273993..1274808) 1 NC_006449.1 hypothetical protein 1274808 3167463 str1433 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141785.1 1273993 R 299768 CDS YP_141786.1 55823345 3166446 complement(1274801..1275595) 1 NC_006449.1 hypothetical protein 1275595 3166446 str1434 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141786.1 1274801 R 299768 CDS YP_141787.1 55823346 3167448 1275778..1276155 1 NC_006449.1 GntR family transcriptional regulator 1276155 3167448 str1435 Streptococcus thermophilus CNRZ1066 GntR family transcriptional regulator YP_141787.1 1275778 D 299768 CDS YP_141788.1 55823347 3167474 1276160..1276858 1 NC_006449.1 ABC transporter ATP binding protein 1276858 3167474 str1436 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141788.1 1276160 D 299768 CDS YP_141789.1 55823348 3167433 1276864..1277655 1 NC_006449.1 ABC transporter permease 1277655 3167433 str1437 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141789.1 1276864 D 299768 CDS YP_141790.1 55823349 3166421 complement(1277705..1278649) 1 NC_006449.1 oligopeptide ABC transporter ATP-binding protein 1278649 amiF1 3166421 amiF1 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter ATP-binding protein YP_141790.1 1277705 R 299768 CDS YP_141791.1 55823350 3167399 complement(1278627..1279712) 1 NC_006449.1 oligopeptide ABC transporter ATP-binding protein 1279712 amiE 3167399 amiE Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter ATP-binding protein YP_141791.1 1278627 R 299768 CDS YP_141792.1 55823351 3167422 complement(1279722..1280648) 1 NC_006449.1 oligopeptide ABC transporter membrane-binding protein 1280648 amiD 3167422 amiD Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter membrane-binding protein YP_141792.1 1279722 R 299768 CDS YP_141793.1 55823352 3167429 complement(1280648..1282141) 1 NC_006449.1 oligopeptide ABC transporter membrane-binding protein 1282141 amiC 3167429 amiC Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter membrane-binding protein YP_141793.1 1280648 R 299768 CDS YP_141794.1 55823353 3167443 complement(1282203..1283021) 1 NC_006449.1 truncated; oligopeptide ABC transporter substrate-binding protein, truncated 1283021 3167443 str1442 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein, truncated YP_141794.1 1282203 R 299768 CDS YP_141795.1 55823354 3167379 complement(1283252..1284169) 1 NC_006449.1 truncated; oligopeptide ABC transporter substrate-binding protein, truncated 1284169 3167379 str1443 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein, truncated YP_141795.1 1283252 R 299768 CDS YP_141796.1 55823355 3167408 1284589..1285935 1 NC_006449.1 IS1193 transposase 1285935 tnp1193 3167408 tnp1193 Streptococcus thermophilus CNRZ1066 IS1193 transposase YP_141796.1 1284589 D 299768 CDS YP_141797.1 55823356 3167445 complement(1285819..1287786) 1 NC_006449.1 oligopeptide ABC transporter substrate-binding protein 1287786 amiA3 3167445 amiA3 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein YP_141797.1 1285819 R 299768 CDS YP_141798.1 55823357 3166434 complement(1288219..1288341) 1 NC_006449.1 truncated; oligopeptide ABC transporter ATP-binding protein, truncated 1288341 3166434 str1447 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter ATP-binding protein, truncated YP_141798.1 1288219 R 299768 CDS YP_141799.1 55823358 3167394 complement(1288354..1288665) 1 NC_006449.1 truncated; oligopeptide ABC transporter ATP-binding protein, truncated 1288665 3167394 str1448 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter ATP-binding protein, truncated YP_141799.1 1288354 R 299768 CDS YP_141800.1 55823359 3167455 complement(1288679..1288972) 1 NC_006449.1 hypothetical protein 1288972 3167455 str1449 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141800.1 1288679 R 299768 CDS YP_141801.1 55823360 3166439 1289279..1290484 1 NC_006449.1 oxalate:formate antiporter 1290484 oxlT 3166439 oxlT Streptococcus thermophilus CNRZ1066 oxalate:formate antiporter YP_141801.1 1289279 D 299768 CDS YP_141802.1 55823361 3167441 complement(1290530..1291168) 1 NC_006449.1 truncated; hypothetical protein 1291168 3167441 str1451 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141802.1 1290530 R 299768 CDS YP_141803.1 55823362 3167421 complement(1291175..1291369) 1 NC_006449.1 truncated; hypothetical protein 1291369 3167421 str1452 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141803.1 1291175 R 299768 CDS YP_141804.1 55823363 3167424 complement(1291318..1291668) 1 NC_006449.1 truncated; hypothetical protein 1291668 3167424 str1453 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141804.1 1291318 R 299768 CDS YP_141805.1 55823364 3166438 complement(1291634..1291939) 1 NC_006449.1 truncated; hypothetical protein 1291939 3166438 str1454 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141805.1 1291634 R 299768 CDS YP_141806.1 55823365 3167389 complement(1291968..1292951) 1 NC_006449.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1292951 eutD 3167389 eutD Streptococcus thermophilus CNRZ1066 phosphotransacetylase YP_141806.1 1291968 R 299768 CDS YP_141807.1 55823366 3166433 complement(1292965..1293861) 1 NC_006449.1 ribosomal large subunit pseudouridine synthase D 1293861 3166433 str1456 Streptococcus thermophilus CNRZ1066 ribosomal large subunit pseudouridine synthase D YP_141807.1 1292965 R 299768 CDS YP_141808.1 55823367 3166415 complement(1293858..1294697) 1 NC_006449.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1294697 ppnK 3166415 ppnK Streptococcus thermophilus CNRZ1066 inorganic polyphosphate/ATP-NAD kinase YP_141808.1 1293858 R 299768 CDS YP_141809.1 55823369 3166207 complement(1294666..1295391) 1 NC_006449.1 GTP pyrophosphokinase 1295391 3166207 str1459 Streptococcus thermophilus CNRZ1066 GTP pyrophosphokinase YP_141809.1 1294666 R 299768 CDS YP_141810.1 55823368 3167357 1295355..1296011 1 NC_006449.1 hypothetical protein 1296011 3167357 str1458 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141810.1 1295355 D 299768 CDS YP_141811.1 55823370 3167465 1296332..1297345 1 NC_006449.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1297345 prsA2 3167465 prsA2 Streptococcus thermophilus CNRZ1066 ribose-phosphate pyrophosphokinase YP_141811.1 1296332 D 299768 CDS YP_141812.1 55823371 3167472 1297349..1298461 1 NC_006449.1 class V aminotransferase 1298461 nifS3 3167472 nifS3 Streptococcus thermophilus CNRZ1066 class V aminotransferase YP_141812.1 1297349 D 299768 CDS YP_141813.1 55823372 3167393 1298463..1298810 1 NC_006449.1 hypothetical protein 1298810 3167393 str1462 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141813.1 1298463 D 299768 CDS YP_141814.1 55823373 3167351 1298918..1299613 1 NC_006449.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1299613 3167351 str1463 Streptococcus thermophilus CNRZ1066 redox-sensing transcriptional repressor Rex YP_141814.1 1298918 D 299768 CDS YP_141815.1 55823374 3167380 1299606..1300301 1 NC_006449.1 glutamine amidotransferase 1300301 3167380 str1464 Streptococcus thermophilus CNRZ1066 glutamine amidotransferase YP_141815.1 1299606 D 299768 CDS YP_141816.1 55823375 3166427 complement(1300354..1301040) 1 NC_006449.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1301040 radC 3166427 radC Streptococcus thermophilus CNRZ1066 DNA repair protein RadC YP_141816.1 1300354 R 299768 CDS YP_141817.1 55823376 3166426 complement(1301219..1302697) 1 NC_006449.1 hypothetical protein 1302697 3166426 str1466 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141817.1 1301219 R 299768 CDS YP_141818.1 55823377 3167457 complement(1302708..1304453) 1 NC_006449.1 polysaccharide biosynthesis protein 1304453 rgpF 3167457 rgpF Streptococcus thermophilus CNRZ1066 polysaccharide biosynthesis protein YP_141818.1 1302708 R 299768 CDS YP_141819.1 55823378 3167439 complement(1304455..1306164) 1 NC_006449.1 polysaccharide biosynthesis protein/ glycosyltransferase 1306164 rgpE 3167439 rgpE Streptococcus thermophilus CNRZ1066 polysaccharide biosynthesis protein/ glycosyltransferase YP_141819.1 1304455 R 299768 CDS YP_141820.1 55823379 3167391 complement(1306173..1307375) 1 NC_006449.1 polysaccharide ABC transporter ATP-binding protein 1307375 rgpD 3167391 rgpD Streptococcus thermophilus CNRZ1066 polysaccharide ABC transporter ATP-binding protein YP_141820.1 1306173 R 299768 CDS YP_141821.1 55823380 3166410 complement(1307375..1308181) 1 NC_006449.1 polysaccharide ABC transporter membrane-spanning protein 1308181 rgpC 3166410 rgpC Streptococcus thermophilus CNRZ1066 polysaccharide ABC transporter membrane-spanning protein YP_141821.1 1307375 R 299768 CDS YP_141822.1 55823381 3166420 complement(1308181..1309122) 1 NC_006449.1 polysaccharide biosynthesis protein/ rhamnosyl transferase 1309122 rgpB 3166420 rgpB Streptococcus thermophilus CNRZ1066 polysaccharide biosynthesis protein/ rhamnosyl transferase YP_141822.1 1308181 R 299768 CDS YP_141823.1 55823382 3167291 complement(1309119..1310267) 1 NC_006449.1 polysaccharide biosynthesis protein/ rhamnosyl transferase 1310267 rgpA 3167291 rgpA Streptococcus thermophilus CNRZ1066 polysaccharide biosynthesis protein/ rhamnosyl transferase YP_141823.1 1309119 R 299768 CDS YP_141824.1 55823383 3167412 complement(1310386..1311168) 1 NC_006449.1 glycosyltransferase teichoic acid biosynthesis protein 1311168 3167412 str1474 Streptococcus thermophilus CNRZ1066 glycosyltransferase teichoic acid biosynthesis protein YP_141824.1 1310386 R 299768 CDS YP_141825.1 55823384 3167428 complement(1311169..1311501) 1 NC_006449.1 hypothetical protein 1311501 3167428 str1475 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141825.1 1311169 R 299768 CDS YP_141826.1 55823385 3167400 complement(1311507..1312196) 1 NC_006449.1 glycosyl transferase 1312196 3167400 str1476 Streptococcus thermophilus CNRZ1066 glycosyl transferase YP_141826.1 1311507 R 299768 CDS YP_141827.1 55823386 3166400 complement(1312279..1312461) 1 NC_006449.1 truncated; glycosyl transferase, truncated 1312461 3166400 str1477 Streptococcus thermophilus CNRZ1066 glycosyl transferase, truncated YP_141827.1 1312279 R 299768 CDS YP_141828.1 55823387 3167376 complement(1312495..1312758) 1 NC_006449.1 truncated; glycosyl transferase, truncated 1312758 3167376 str1478 Streptococcus thermophilus CNRZ1066 glycosyl transferase, truncated YP_141828.1 1312495 R 299768 CDS YP_141829.1 55823388 3166393 complement(1312823..1313809) 1 NC_006449.1 glycosyl transferase 1313809 3166393 str1479 Streptococcus thermophilus CNRZ1066 glycosyl transferase YP_141829.1 1312823 R 299768 CDS YP_141830.1 55823389 3166405 complement(1313806..1315065) 1 NC_006449.1 polysaccharide/teichoic acid transporter 1315065 3166405 str1480 Streptococcus thermophilus CNRZ1066 polysaccharide/teichoic acid transporter YP_141830.1 1313806 R 299768 CDS YP_141831.1 55823390 3167415 complement(1315186..1316058) 1 NC_006449.1 dTDP-4-keto-L-rhamnose reductase 1316058 rmlD 3167415 rmlD Streptococcus thermophilus CNRZ1066 dTDP-4-keto-L-rhamnose reductase YP_141831.1 1315186 R 299768 CDS YP_141832.1 55823391 3166895 complement(1316155..1317081) 1 NC_006449.1 glycosyl transferase family protein 1317081 3166895 str1485 Streptococcus thermophilus CNRZ1066 glycosyl transferase family protein YP_141832.1 1316155 R 299768 CDS YP_141833.1 55823392 3167378 complement(1317091..1317456) 1 NC_006449.1 hypothetical protein 1317456 3167378 str1487 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141833.1 1317091 R 299768 CDS YP_141834.1 55823393 3166397 complement(1317480..1318589) 1 NC_006449.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1318589 rpoD 3166397 rpoD Streptococcus thermophilus CNRZ1066 RNA polymerase sigma factor RpoD YP_141834.1 1317480 R 299768 CDS YP_141835.1 55823394 3167377 complement(1318593..1320404) 1 NC_006449.1 synthesizes RNA primers at the replication forks; DNA primase 1320404 dnaG 3167377 dnaG Streptococcus thermophilus CNRZ1066 DNA primase YP_141835.1 1318593 R 299768 CDS YP_141836.2 161936366 3167292 complement(1320776..1320952) 1 NC_006449.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1320952 rpsU 3167292 rpsU Streptococcus thermophilus CNRZ1066 30S ribosomal protein S21 YP_141836.2 1320776 R 299768 CDS YP_141837.1 55823396 3167402 1321288..1322286 1 NC_006449.1 IS1239 transposase 1322286 tnp1239 3167402 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_141837.1 1321288 D 299768 CDS YP_141838.1 55823397 3167363 complement(1322392..1323186) 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 1323186 3167363 str1492 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_141838.1 1322392 R 299768 CDS YP_141839.1 55823398 3167411 complement(1323279..1324391) 1 NC_006449.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 1324391 3167411 str1493 Streptococcus thermophilus CNRZ1066 transaminase YP_141839.1 1323279 R 299768 CDS YP_141840.1 55823399 3167293 complement(1324735..1325532) 1 NC_006449.1 ABC transporter substrate-binding protein, amino acid 1325532 3167293 str1494 Streptococcus thermophilus CNRZ1066 ABC transporter substrate-binding protein, amino acid YP_141840.1 1324735 R 299768 CDS YP_141841.1 55823400 3167359 complement(1325529..1326365) 1 NC_006449.1 ABC transporter substrate-binding protein, amino acid 1326365 3167359 str1495 Streptococcus thermophilus CNRZ1066 ABC transporter substrate-binding protein, amino acid YP_141841.1 1325529 R 299768 CDS YP_141842.1 55823401 3167367 complement(1326573..1327037) 1 NC_006449.1 MutT/nudix family protein 1327037 3167367 str1496 Streptococcus thermophilus CNRZ1066 MutT/nudix family protein YP_141842.1 1326573 R 299768 CDS YP_141843.1 55823402 3166380 complement(1327082..1329088) 1 NC_006449.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1329088 uvrB 3166380 uvrB Streptococcus thermophilus CNRZ1066 excinuclease ABC subunit B YP_141843.1 1327082 R 299768 CDS YP_141844.1 55823403 3167366 complement(1329220..1329660) 1 NC_006449.1 hypothetical protein 1329660 3167366 str1498 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141844.1 1329220 R 299768 CDS YP_141845.1 55823404 3167371 complement(1329833..1330183) 1 NC_006449.1 hypothetical protein 1330183 3167371 str1499 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141845.1 1329833 R 299768 CDS YP_141846.1 55823405 3166379 complement(1330415..1330696) 1 NC_006449.1 hypothetical protein 1330696 3166379 str1500 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141846.1 1330415 R 299768 CDS YP_141847.1 55823406 3167356 1330895..1333105 1 NC_006449.1 glutamine ABC transporter permease 1333105 gnlP 3167356 gnlP Streptococcus thermophilus CNRZ1066 glutamine ABC transporter permease YP_141847.1 1330895 D 299768 CDS YP_141848.1 55823407 3167410 1333105..1333845 1 NC_006449.1 glutamine ABC transporter ATP-binding protein 1333845 gnlQ 3167410 gnlQ Streptococcus thermophilus CNRZ1066 glutamine ABC transporter ATP-binding protein YP_141848.1 1333105 D 299768 CDS YP_141849.1 55823408 3166378 complement(1333918..1334115) 1 NC_006449.1 hypothetical protein 1334115 3166378 str1503 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141849.1 1333918 R 299768 CDS YP_141850.2 161936365 3167352 complement(1334282..1335589) 1 NC_006449.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1335589 obgE 3167352 obgE Streptococcus thermophilus CNRZ1066 GTPase ObgE YP_141850.2 1334282 R 299768 CDS YP_141851.1 55823410 3166376 complement(1335899..1336630) 1 NC_006449.1 ribosomal small subunit pseudouridine synthase A 1336630 rsuA2 3166376 rsuA2 Streptococcus thermophilus CNRZ1066 ribosomal small subunit pseudouridine synthase A YP_141851.1 1335899 R 299768 CDS YP_141852.1 55823411 3167370 complement(1336631..1336864) 1 NC_006449.1 hypothetical protein 1336864 3167370 str1506 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141852.1 1336631 R 299768 CDS YP_141853.1 55823412 3167470 complement(1337000..1337293) 1 NC_006449.1 hypothetical protein 1337293 3167470 str1507 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141853.1 1337000 R 299768 CDS YP_141854.1 55823413 3167369 1337314..1337415 1 NC_006449.1 hypothetical protein 1337415 3167369 str1508 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141854.1 1337314 D 299768 CDS YP_141855.1 55823414 3167353 1337576..1338166 1 NC_006449.1 hypothetical protein 1338166 3167353 str1509 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141855.1 1337576 D 299768 CDS YP_141856.1 55823415 3166381 1338166..1338492 1 NC_006449.1 hypothetical protein 1338492 3166381 str1510 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141856.1 1338166 D 299768 CDS YP_141857.1 55823416 3167396 complement(1338715..1339578) 1 NC_006449.1 MutR family transcriptional regulator 1339578 3167396 str1511 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_141857.1 1338715 R 299768 CDS YP_141858.1 55823417 3167269 1339927..1341222 1 NC_006449.1 hypothetical protein 1341222 3167269 str1512 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141858.1 1339927 D 299768 CDS YP_141859.1 55823418 3167387 1341224..1342795 1 NC_006449.1 ABC transporter ATP binding/permease 1342795 3167387 str1513 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding/permease YP_141859.1 1341224 D 299768 CDS YP_141860.1 55823419 3166823 1343077..1343508 1 NC_006449.1 hypothetical protein 1343508 3166823 str1514 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141860.1 1343077 D 299768 CDS YP_141861.1 55823420 3166215 1343535..1343903 1 NC_006449.1 hypothetical protein 1343903 3166215 str1515 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141861.1 1343535 D 299768 CDS YP_141862.1 55823421 3165757 complement(1343932..1344396) 1 NC_006449.1 hypothetical protein 1344396 3165757 str1516 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141862.1 1343932 R 299768 CDS YP_141863.1 55823422 3167373 1345408..1346298 1 NC_006449.1 permease 1346298 3167373 str1517 Streptococcus thermophilus CNRZ1066 permease YP_141863.1 1345408 D 299768 CDS YP_141864.1 55823423 3165952 complement(1346336..1346587) 1 NC_006449.1 hypothetical protein 1346587 3165952 str1518 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141864.1 1346336 R 299768 CDS YP_141865.1 55823424 3166713 complement(1346799..1347446) 1 NC_006449.1 phosphoserine phosphatase 1347446 serB 3166713 serB Streptococcus thermophilus CNRZ1066 phosphoserine phosphatase YP_141865.1 1346799 R 299768 CDS YP_141866.1 55823425 3165851 complement(1347558..1349252) 1 NC_006449.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 1349252 ezrA 3165851 ezrA Streptococcus thermophilus CNRZ1066 septation ring formation regulator EzrA YP_141866.1 1347558 R 299768 CDS YP_141867.1 55823426 3166358 complement(1349379..1351331) 1 NC_006449.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 1351331 gyrB 3166358 gyrB Streptococcus thermophilus CNRZ1066 DNA gyrase subunit B YP_141867.1 1349379 R 299768 CDS YP_141868.1 55823427 3165843 complement(1351332..1351937) 1 NC_006449.1 HAD superfamily hydrolase 1351937 3165843 str1522 Streptococcus thermophilus CNRZ1066 HAD superfamily hydrolase YP_141868.1 1351332 R 299768 CDS YP_141869.1 55823428 3165669 complement(1351978..1352700) 1 NC_006449.1 hypothetical protein 1352700 3165669 str1523 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141869.1 1351978 R 299768 CDS YP_141870.1 55823429 3165804 complement(1352666..1353064) 1 NC_006449.1 hypothetical protein 1353064 3165804 str1524 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141870.1 1352666 R 299768 CDS YP_141871.1 55823430 3166639 complement(1353320..1353673) 1 NC_006449.1 hypothetical protein 1353673 3166639 str1525 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141871.1 1353320 R 299768 CDS YP_141872.1 55823431 3166036 complement(1353708..1354046) 1 NC_006449.1 truncated; methylguanine-DNA methyltransferase, truncated 1354046 3166036 str1526 Streptococcus thermophilus CNRZ1066 methylguanine-DNA methyltransferase, truncated YP_141872.1 1353708 R 299768 CDS YP_141873.1 55823432 3166124 complement(1354259..1355437) 1 NC_006449.1 D-3-phosphoglycerate dehydrogenase 1355437 serA 3166124 serA Streptococcus thermophilus CNRZ1066 D-3-phosphoglycerate dehydrogenase YP_141873.1 1354259 R 299768 CDS YP_141874.1 55823433 3166062 complement(1355456..1356013) 1 NC_006449.1 acetyltransferase 1356013 3166062 str1528 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_141874.1 1355456 R 299768 CDS YP_141875.1 55823434 3166370 complement(1356025..1357119) 1 NC_006449.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1357119 serC 3166370 serC Streptococcus thermophilus CNRZ1066 phosphoserine aminotransferase YP_141875.1 1356025 R 299768 CDS YP_141876.1 55823435 3166425 complement(1357273..1357971) 1 NC_006449.1 truncated; transcriptional regulator, truncated 1357971 3166425 str1530 Streptococcus thermophilus CNRZ1066 transcriptional regulator, truncated YP_141876.1 1357273 R 299768 CDS YP_141877.1 55823436 3166051 complement(1357886..1358179) 1 NC_006449.1 truncated; transcriptional regulator, truncated 1358179 3166051 str1531 Streptococcus thermophilus CNRZ1066 transcriptional regulator, truncated YP_141877.1 1357886 R 299768 CDS YP_141878.1 55823437 3166291 1358225..1358620 1 NC_006449.1 glyoxalase I/lactoylglutathione lyase 1358620 gloA 3166291 gloA Streptococcus thermophilus CNRZ1066 glyoxalase I/lactoylglutathione lyase YP_141878.1 1358225 D 299768 CDS YP_141879.1 55823438 3166257 complement(1358664..1359413) 1 NC_006449.1 SPFH domain-containing protein/band 7 family protein 1359413 3166257 str1533 Streptococcus thermophilus CNRZ1066 SPFH domain-containing protein/band 7 family protein YP_141879.1 1358664 R 299768 CDS YP_141880.1 55823439 3166766 complement(1359772..1360842) 1 NC_006449.1 spermidine/putrescine ABC transporter periplasmic protein 1360842 potD 3166766 potD Streptococcus thermophilus CNRZ1066 spermidine/putrescine ABC transporter periplasmic protein YP_141880.1 1359772 R 299768 CDS YP_141881.1 55823440 3166264 complement(1360832..1361635) 1 NC_006449.1 spermidine/putrescine ABC transporter permease 1361635 potC 3166264 potC Streptococcus thermophilus CNRZ1066 spermidine/putrescine ABC transporter permease YP_141881.1 1360832 R 299768 CDS YP_141882.1 55823441 3166368 complement(1361608..1362423) 1 NC_006449.1 spermidine/putrescine ABC transporter permease 1362423 potB 3166368 potB Streptococcus thermophilus CNRZ1066 spermidine/putrescine ABC transporter permease YP_141882.1 1361608 R 299768 CDS YP_141883.1 55823442 3166293 complement(1362386..1363540) 1 NC_006449.1 spermidine/putrescine ABC transporter ATP-binding protein 1363540 potA 3166293 potA Streptococcus thermophilus CNRZ1066 spermidine/putrescine ABC transporter ATP-binding protein YP_141883.1 1362386 R 299768 CDS YP_141884.1 55823443 3166564 complement(1363585..1364562) 1 NC_006449.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1364562 murB 3166564 murB Streptococcus thermophilus CNRZ1066 UDP-N-acetylenolpyruvoylglucosamine reductase YP_141884.1 1363585 R 299768 CDS YP_141885.1 55823444 3166447 complement(1364677..1365168) 1 NC_006449.1 hydroxymethylpterin pyrophosphokinase 1365168 folK 3166447 folK Streptococcus thermophilus CNRZ1066 hydroxymethylpterin pyrophosphokinase YP_141885.1 1364677 R 299768 CDS YP_141886.1 55823445 3166645 complement(1365165..1365524) 1 NC_006449.1 dihydroneopterin aldolase 1365524 folQ 3166645 folQ Streptococcus thermophilus CNRZ1066 dihydroneopterin aldolase YP_141886.1 1365165 R 299768 CDS YP_141887.1 55823446 3166267 1365721..1367196 1 NC_006449.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1367196 amyL 3166267 amyL Streptococcus thermophilus CNRZ1066 cytoplasmic alpha-amylase YP_141887.1 1365721 D 299768 CDS YP_141888.1 55823447 3165892 complement(1367228..1368028) 1 NC_006449.1 dihydropteroate synthase 1368028 folP 3165892 folP Streptococcus thermophilus CNRZ1066 dihydropteroate synthase YP_141888.1 1367228 R 299768 CDS YP_141889.1 55823448 3166367 complement(1368057..1368620) 1 NC_006449.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1368620 folE 3166367 folE Streptococcus thermophilus CNRZ1066 GTP cyclohydrolase I YP_141889.1 1368057 R 299768 CDS YP_141890.1 55823449 3165947 complement(1368766..1370610) 1 NC_006449.1 aminoacid specific permease 1370610 3165947 str1545 Streptococcus thermophilus CNRZ1066 aminoacid specific permease YP_141890.1 1368766 R 299768 CDS YP_141891.1 55823450 3165760 complement(1370674..1371936) 1 NC_006449.1 folylpolyglutamate synthase / dihydrofolate synthase 1371936 folC2 3165760 folC2 Streptococcus thermophilus CNRZ1066 folylpolyglutamate synthase / dihydrofolate synthase YP_141891.1 1370674 R 299768 CDS YP_141892.1 55823451 3166263 complement(1372079..1372327) 1 NC_006449.1 hypothetical protein 1372327 3166263 str1547 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141892.1 1372079 R 299768 CDS YP_141893.1 55823452 3166514 complement(1372339..1372611) 1 NC_006449.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1372611 rpsP 3166514 rpsP Streptococcus thermophilus CNRZ1066 30S ribosomal protein S16 YP_141893.1 1372339 R 299768 CDS YP_141894.1 55823453 3166731 1373044..1373922 1 NC_006449.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1373922 tehB 3166731 tehB Streptococcus thermophilus CNRZ1066 tellurite resistance protein TehB YP_141894.1 1373044 D 299768 CDS YP_141895.1 55823454 3166200 1375077..1375904 1 NC_006449.1 3'-exo-deoxyribonuclease 1375904 exoA 3166200 exoA Streptococcus thermophilus CNRZ1066 3'-exo-deoxyribonuclease YP_141895.1 1375077 D 299768 CDS YP_141896.1 55823455 3166623 1375978..1376457 1 NC_006449.1 citrulline cluster-linked gene 1376457 3166623 str1551 Streptococcus thermophilus CNRZ1066 citrulline cluster-linked gene YP_141896.1 1375978 D 299768 CDS YP_141897.1 55823456 3166529 complement(1376577..1377215) 1 NC_006449.1 truncated; hypothetical protein 1377215 3166529 str1552 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141897.1 1376577 R 299768 CDS YP_141898.1 55823457 3166419 complement(1377406..1378419) 1 NC_006449.1 similar to YegS from E. coli; lipid kinase 1378419 3166419 str1553 Streptococcus thermophilus CNRZ1066 lipid kinase YP_141898.1 1377406 R 299768 CDS YP_141899.1 55823458 3166565 complement(1378429..1380387) 1 NC_006449.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1380387 ligA 3166565 ligA Streptococcus thermophilus CNRZ1066 NAD-dependent DNA ligase LigA YP_141899.1 1378429 R 299768 CDS YP_141900.1 55823459 3165632 complement(1380438..1380959) 1 NC_006449.1 hypothetical protein 1380959 3165632 str1555 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141900.1 1380438 R 299768 CDS YP_141901.1 55823460 3166085 complement(1381038..1381997) 1 NC_006449.1 tRNA-processing ribonuclease BN 1381997 3166085 str1556 Streptococcus thermophilus CNRZ1066 tRNA-processing ribonuclease BN YP_141901.1 1381038 R 299768 CDS YP_141902.1 55823461 3165909 complement(1381999..1382859) 1 NC_006449.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1382859 pepM 3165909 pepM Streptococcus thermophilus CNRZ1066 methionine aminopeptidase YP_141902.1 1381999 R 299768 CDS YP_141903.1 55823462 3166554 complement(1382903..1384183) 1 NC_006449.1 hypothetical protein 1384183 3166554 str1558 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141903.1 1382903 R 299768 CDS YP_141904.1 55823463 3166309 complement(1384176..1384763) 1 NC_006449.1 acetyltransferase 1384763 3166309 str1559 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_141904.1 1384176 R 299768 CDS YP_141905.1 55823464 3166655 complement(1384787..1386058) 1 NC_006449.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1386058 murZ 3166655 murZ Streptococcus thermophilus CNRZ1066 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_141905.1 1384787 R 299768 CDS YP_141906.1 55823465 3166387 complement(1386135..1388375) 1 NC_006449.1 late competence protein required for DNA uptake 1388375 comEC 3166387 comEC Streptococcus thermophilus CNRZ1066 late competence protein required for DNA uptake YP_141906.1 1386135 R 299768 CDS YP_141907.1 55823466 3166173 complement(1388365..1389060) 1 NC_006449.1 late competence protein required for DNA binding and uptake 1389060 comEA 3166173 comEA Streptococcus thermophilus CNRZ1066 late competence protein required for DNA binding and uptake YP_141907.1 1388365 R 299768 CDS YP_141908.1 55823467 3166463 complement(1389168..1389923) 1 NC_006449.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 1389923 3166463 str1563 Streptococcus thermophilus CNRZ1066 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_141908.1 1389168 R 299768 CDS YP_141909.1 55823468 3165739 1390123..1390656 1 NC_006449.1 truncated; peptidoglycan GlcNAc deacetylase, truncated 1390656 3165739 str1564 Streptococcus thermophilus CNRZ1066 peptidoglycan GlcNAc deacetylase, truncated YP_141909.1 1390123 D 299768 CDS YP_141910.1 55823469 3165759 1390701..1390988 1 NC_006449.1 truncated; peptidoglycan GlcNAc deacetylase, truncated 1390988 3165759 str1565 Streptococcus thermophilus CNRZ1066 peptidoglycan GlcNAc deacetylase, truncated YP_141910.1 1390701 D 299768 CDS YP_141911.1 55823470 3166680 1391038..1391802 1 NC_006449.1 hypothetical protein 1391802 3166680 str1566 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141911.1 1391038 D 299768 CDS YP_141912.1 55823471 3166126 1391806..1392075 1 NC_006449.1 hypothetical protein 1392075 3166126 str1567 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141912.1 1391806 D 299768 CDS YP_141913.1 55823472 3165748 complement(1392632..1394218) 1 NC_006449.1 ATP-dependent RNA helicase 1394218 rheA 3165748 rheA Streptococcus thermophilus CNRZ1066 ATP-dependent RNA helicase YP_141913.1 1392632 R 299768 CDS YP_141914.1 55823473 3166127 complement(1394409..1395317) 1 NC_006449.1 cation transporter 1395317 corA1 3166127 corA1 Streptococcus thermophilus CNRZ1066 cation transporter YP_141914.1 1394409 R 299768 CDS YP_141915.1 55823474 3166767 complement(1395331..1395711) 1 NC_006449.1 hypothetical protein 1395711 3166767 str1570 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141915.1 1395331 R 299768 CDS YP_141916.1 55823475 3166143 1396012..1396587 1 NC_006449.1 hypothetical protein 1396587 3166143 str1571 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141916.1 1396012 D 299768 CDS YP_141917.1 55823476 3166136 1397038..1397901 1 NC_006449.1 MutR family transcriptional regulator 1397901 3166136 str1572 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_141917.1 1397038 D 299768 CDS YP_141918.1 55823477 3165711 1398018..1399196 1 NC_006449.1 macrolide-efflux protein 1399196 3165711 str1573 Streptococcus thermophilus CNRZ1066 macrolide-efflux protein YP_141918.1 1398018 D 299768 CDS YP_141919.1 55823478 3165917 complement(1399442..1400986) 1 NC_006449.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1400986 prfC 3165917 prfC Streptococcus thermophilus CNRZ1066 peptide chain release factor 3 YP_141919.1 1399442 R 299768 CDS YP_141920.1 55823479 3165678 complement(1401336..1402001) 1 NC_006449.1 hypothetical protein 1402001 3165678 str1575 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141920.1 1401336 R 299768 CDS YP_141921.1 55823480 3166027 complement(1402090..1403463) 1 NC_006449.1 UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase 1403463 murF 3166027 murF Streptococcus thermophilus CNRZ1066 UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase YP_141921.1 1402090 R 299768 CDS YP_141922.1 55823481 3166739 1403710..1404303 1 NC_006449.1 hypothetical protein 1404303 3166739 str1577 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141922.1 1403710 D 299768 CDS YP_141923.1 55823482 3166023 1404272..1404814 1 NC_006449.1 hypothetical protein 1404814 3166023 str1578 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141923.1 1404272 D 299768 CDS YP_141924.1 55823483 3166221 complement(1405053..1405907) 1 NC_006449.1 amino acid ABC transporter substrate-binding protein 1405907 3166221 str1579 Streptococcus thermophilus CNRZ1066 amino acid ABC transporter substrate-binding protein YP_141924.1 1405053 R 299768 CDS YP_141925.1 55823484 3166650 complement(1405950..1406771) 1 NC_006449.1 amino acid (glutamine) ABC transporter ATP-binding protein 1406771 3166650 str1580 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter ATP-binding protein YP_141925.1 1405950 R 299768 CDS YP_141926.1 55823485 3165713 complement(1406710..1407405) 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 1407405 3165713 str1581 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141926.1 1406710 R 299768 CDS YP_141927.1 55823486 3166503 complement(1407347..1408027) 1 NC_006449.1 amino acid (glutamine) ABC transporter permease 1408027 3166503 str1582 Streptococcus thermophilus CNRZ1066 amino acid (glutamine) ABC transporter permease YP_141927.1 1407347 R 299768 CDS YP_141928.1 55823487 3165932 complement(1408352..1409398) 1 NC_006449.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1409398 ddl 3165932 ddl Streptococcus thermophilus CNRZ1066 D-alanyl-alanine synthetase A YP_141928.1 1408352 R 299768 CDS YP_141929.1 55823488 3166131 complement(1409560..1409763) 1 NC_006449.1 copper chaperone - copper transport ATPase 1409763 copZ 3166131 copZ Streptococcus thermophilus CNRZ1066 copper chaperone - copper transport ATPase YP_141929.1 1409560 R 299768 CDS YP_141930.1 55823489 3165656 complement(1409838..1412066) 1 NC_006449.1 cation transporting ATPase, copper transport 1412066 copA 3165656 copA Streptococcus thermophilus CNRZ1066 cation transporting ATPase, copper transport YP_141930.1 1409838 R 299768 CDS YP_141931.1 55823490 3166790 complement(1412070..1412501) 1 NC_006449.1 negative transcriptional regulator - copper transport operon 1412501 copY 3166790 copY Streptococcus thermophilus CNRZ1066 negative transcriptional regulator - copper transport operon YP_141931.1 1412070 R 299768 CDS YP_141932.1 55823491 3166783 complement(1412645..1413427) 1 NC_006449.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1413427 trpA 3166783 trpA Streptococcus thermophilus CNRZ1066 tryptophan synthase subunit alpha YP_141932.1 1412645 R 299768 CDS YP_141933.1 55823492 3165655 complement(1413431..1414639) 1 NC_006449.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1414639 trpB 3165655 trpB Streptococcus thermophilus CNRZ1066 tryptophan synthase subunit beta YP_141933.1 1413431 R 299768 CDS YP_141934.1 55823493 3166152 complement(1414636..1415247) 1 NC_006449.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1415247 trpF 3166152 trpF Streptococcus thermophilus CNRZ1066 N-(5'-phosphoribosyl)anthranilate isomerase YP_141934.1 1414636 R 299768 CDS YP_141935.1 55823494 3166265 complement(1415204..1415971) 1 NC_006449.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1415971 trpC 3166265 trpC Streptococcus thermophilus CNRZ1066 indole-3-glycerol phosphate synthase YP_141935.1 1415204 R 299768 CDS YP_141936.1 55823495 3166678 complement(1415968..1416972) 1 NC_006449.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1416972 trpD 3166678 trpD Streptococcus thermophilus CNRZ1066 anthranilate phosphoribosyltransferase YP_141936.1 1415968 R 299768 CDS YP_141937.1 55823496 3166141 complement(1417059..1417625) 1 NC_006449.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1417625 trpG 3166141 trpG Streptococcus thermophilus CNRZ1066 anthranilate synthase component II YP_141937.1 1417059 R 299768 CDS YP_141938.1 55823497 3166087 complement(1417622..1418992) 1 NC_006449.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1418992 trpE 3166087 trpE Streptococcus thermophilus CNRZ1066 anthranilate synthase component I YP_141938.1 1417622 R 299768 CDS YP_141939.1 55823498 3166604 complement(1419054..1419344) 1 NC_006449.1 hypothetical protein 1419344 3166604 str1594 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141939.1 1419054 R 299768 CDS YP_141940.1 55823499 3166408 complement(1419930..1420280) 1 NC_006449.1 hypothetical protein 1420280 3166408 str1595 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141940.1 1419930 R 299768 CDS YP_141941.1 55823500 3166884 complement(1420362..1422749) 1 NC_006449.1 cation transporting ATPase 1422749 ctpE 3166884 ctpE Streptococcus thermophilus CNRZ1066 cation transporting ATPase YP_141941.1 1420362 R 299768 CDS YP_141942.1 55823501 3166628 complement(1422982..1423377) 1 NC_006449.1 hypothetical protein 1423377 3166628 str1597 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141942.1 1422982 R 299768 CDS YP_141943.1 55823502 3166717 1423686..1423985 1 NC_006449.1 hypothetical protein 1423985 3166717 str1598 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141943.1 1423686 D 299768 CDS YP_141944.1 55823503 3166495 complement(1424143..1424433) 1 NC_006449.1 hypothetical protein 1424433 3166495 str1599 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141944.1 1424143 R 299768 CDS YP_141945.1 55823504 3166211 complement(1424606..1425277) 1 NC_006449.1 MerR family transcriptional regulator 1425277 3166211 str1600 Streptococcus thermophilus CNRZ1066 MerR family transcriptional regulator YP_141945.1 1424606 R 299768 CDS YP_141946.1 55823505 3166916 complement(1425444..1426034) 1 NC_006449.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1426034 dnaQ 3166916 dnaQ Streptococcus thermophilus CNRZ1066 DNA polymerase III subunit epsilon YP_141946.1 1425444 R 299768 CDS YP_141947.1 55823506 3166262 complement(1426084..1426620) 1 NC_006449.1 hypothetical protein 1426620 3166262 str1602 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141947.1 1426084 R 299768 CDS YP_141948.1 55823507 3166294 1427131..1427490 1 NC_006449.1 hypothetical protein 1427490 3166294 str1603 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141948.1 1427131 D 299768 CDS YP_141949.1 55823508 3166567 complement(1427638..1429356) 1 NC_006449.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1429356 ilvD1 3166567 ilvD1 Streptococcus thermophilus CNRZ1066 dihydroxy-acid dehydratase YP_141949.1 1427638 R 299768 CDS YP_141950.1 55823509 3166720 1429469..1430650 1 NC_006449.1 hypothetical protein 1430650 3166720 str1605 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141950.1 1429469 D 299768 CDS YP_141951.1 55823510 3166516 complement(1430886..1431527) 1 NC_006449.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1431527 trmB 3166516 trmB Streptococcus thermophilus CNRZ1066 tRNA (guanine-N(7)-)-methyltransferase YP_141951.1 1430886 R 299768 CDS YP_141952.1 55823511 3166261 complement(1431537..1432328) 1 NC_006449.1 hypothetical protein 1432328 3166261 str1607 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141952.1 1431537 R 299768 CDS YP_141953.1 55823512 3165936 complement(1432386..1433423) 1 NC_006449.1 ABC transporter permease 1433423 3165936 str1608 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_141953.1 1432386 R 299768 CDS YP_141954.1 55823513 3166865 complement(1433420..1434151) 1 NC_006449.1 ABC transporter ATP binding protein 1434151 3166865 str1609 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141954.1 1433420 R 299768 CDS YP_141955.1 55823514 3165935 1434216..1434635 1 NC_006449.1 cell cycle regulation histidine triad (HIT) protein 1434635 hit 3165935 hit Streptococcus thermophilus CNRZ1066 cell cycle regulation histidine triad (HIT) protein YP_141955.1 1434216 D 299768 CDS YP_141956.1 55823515 3166719 1434632..1434940 1 NC_006449.1 hypothetical protein 1434940 3166719 str1611 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141956.1 1434632 D 299768 CDS YP_141957.1 55823516 3165934 complement(1435492..1435662) 1 NC_006449.1 hypothetical protein 1435662 3165934 str1612 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141957.1 1435492 R 299768 CDS YP_141958.1 55823517 3165937 complement(1435732..1436367) 1 NC_006449.1 hypothetical protein 1436367 3165937 str1613 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141958.1 1435732 R 299768 CDS YP_141959.1 55823518 3165940 complement(1436917..1439016) 1 NC_006449.1 ATP-dependent proteinase ATP-binding subunit 1439016 clpL 3165940 clpL Streptococcus thermophilus CNRZ1066 ATP-dependent proteinase ATP-binding subunit YP_141959.1 1436917 R 299768 CDS YP_141960.1 55823519 3165782 complement(1439731..1440822) 1 NC_006449.1 hypothetical protein 1440822 3165782 str1615 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141960.1 1439731 R 299768 CDS YP_141961.1 55823520 3165707 complement(1440829..1441698) 1 NC_006449.1 hypothetical protein 1441698 3165707 str1616 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141961.1 1440829 R 299768 CDS YP_141962.1 55823521 3165708 complement(1441894..1442247) 1 NC_006449.1 hypothetical protein 1442247 3165708 str1617 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141962.1 1441894 R 299768 CDS YP_141963.1 55823522 3165709 complement(1442271..1442861) 1 NC_006449.1 hypothetical protein 1442861 3165709 str1618 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141963.1 1442271 R 299768 CDS YP_141964.1 55823523 3165938 complement(1442858..1443490) 1 NC_006449.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1443490 nadD 3165938 nadD Streptococcus thermophilus CNRZ1066 nicotinic acid mononucleotide adenylyltransferase YP_141964.1 1442858 R 299768 CDS YP_141965.1 55823524 3165796 complement(1443594..1443911) 1 NC_006449.1 hypothetical protein 1443911 3165796 str1620 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141965.1 1443594 R 299768 CDS YP_141966.1 55823525 3165710 complement(1444150..1445268) 1 NC_006449.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1445268 3165710 str1621 Streptococcus thermophilus CNRZ1066 GTP-binding protein YqeH YP_141966.1 1444150 R 299768 CDS YP_141967.1 55823526 3165705 complement(1445268..1445795) 1 NC_006449.1 hypothetical protein 1445795 3165705 str1622 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141967.1 1445268 R 299768 CDS YP_141968.1 55823527 3165721 complement(1445932..1446846) 1 NC_006449.1 permease 1446846 3165721 str1623 Streptococcus thermophilus CNRZ1066 permease YP_141968.1 1445932 R 299768 CDS YP_141969.1 55823528 3165722 complement(1446923..1447306) 1 NC_006449.1 hypothetical protein 1447306 3165722 str1624 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141969.1 1446923 R 299768 CDS YP_141970.1 55823529 3165809 complement(1447404..1448846) 1 NC_006449.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1448846 gatB 3165809 gatB Streptococcus thermophilus CNRZ1066 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_141970.1 1447404 R 299768 CDS YP_141971.1 55823530 3165808 complement(1448846..1450312) 1 NC_006449.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1450312 gatA 3165808 gatA Streptococcus thermophilus CNRZ1066 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_141971.1 1448846 R 299768 CDS YP_141972.2 161936364 3165797 complement(1450312..1450614) 1 NC_006449.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1450614 gatC 3165797 gatC Streptococcus thermophilus CNRZ1066 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_141972.2 1450312 R 299768 CDS YP_141973.1 55823532 3165810 complement(1450754..1451008) 1 NC_006449.1 hypothetical protein 1451008 3165810 str1628 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141973.1 1450754 R 299768 CDS YP_141974.1 55823533 3165939 complement(1451021..1451230) 1 NC_006449.1 hypothetical protein 1451230 3165939 str1629 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141974.1 1451021 R 299768 CDS YP_141975.1 55823534 3166797 complement(1451546..1452091) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 1452091 3166797 str1630 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141975.1 1451546 R 299768 CDS YP_141976.1 55823535 3165703 complement(1452095..1452874) 1 NC_006449.1 truncated; 6-phospho-beta-glucosidase 1452874 3165703 str1631 Streptococcus thermophilus CNRZ1066 6-phospho-beta-glucosidase YP_141976.1 1452095 R 299768 CDS YP_141977.1 55823536 3166807 complement(1453140..1453667) 1 NC_006449.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1453667 msrA2 3166807 msrA2 Streptococcus thermophilus CNRZ1066 methionine sulfoxide reductase A YP_141977.1 1453140 R 299768 CDS YP_141978.1 55823537 3165799 complement(1453661..1454512) 1 NC_006449.1 ABC transporter substrate binding protein 1454512 3165799 str1633 Streptococcus thermophilus CNRZ1066 ABC transporter substrate binding protein YP_141978.1 1453661 R 299768 CDS YP_141979.1 55823538 3166805 complement(1454632..1455183) 1 NC_006449.1 pyrazinamidase/nicotinamidase 1455183 entB 3166805 entB Streptococcus thermophilus CNRZ1066 pyrazinamidase/nicotinamidase YP_141979.1 1454632 R 299768 CDS YP_141980.1 55823539 3166800 complement(1455246..1456031) 1 NC_006449.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1456031 codY 3166800 codY Streptococcus thermophilus CNRZ1066 transcriptional repressor CodY YP_141980.1 1455246 R 299768 CDS YP_141981.1 55823540 3166798 complement(1456291..1457505) 1 NC_006449.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 1457505 aspC2 3166798 aspC2 Streptococcus thermophilus CNRZ1066 aminotransferase YP_141981.1 1456291 R 299768 CDS YP_141982.1 55823541 3165958 1457860..1458312 1 NC_006449.1 hypothetical protein 1458312 3165958 str1637 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141982.1 1457860 D 299768 CDS YP_141983.1 55823542 3165955 1458646..1458900 1 NC_006449.1 truncated; hypothetical protein 1458900 3165955 str1638 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141983.1 1458646 D 299768 CDS YP_141984.1 55823543 3165956 complement(1459279..1459749) 1 NC_006449.1 hypothetical protein 1459749 3165956 str1639 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141984.1 1459279 R 299768 CDS YP_141985.1 55823544 3166632 complement(1459955..1460755) 1 NC_006449.1 pyruvate-formate lyase activating enzyme 1460755 pflA 3166632 pflA Streptococcus thermophilus CNRZ1066 pyruvate-formate lyase activating enzyme YP_141985.1 1459955 R 299768 CDS YP_141986.1 55823545 3165954 complement(1461751..1463082) 1 NC_006449.1 hemolysin 1463082 hlyX 3165954 hlyX Streptococcus thermophilus CNRZ1066 hemolysin YP_141986.1 1461751 R 299768 CDS YP_141987.1 55823546 3166803 1463195..1463977 1 NC_006449.1 ABC transporter ATP binding protein 1463977 3166803 str1642 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_141987.1 1463195 D 299768 CDS YP_141988.1 55823547 3166806 complement(1464596..1466662) 1 NC_006449.1 Na+/H+ antiporter 1466662 nha 3166806 nha Streptococcus thermophilus CNRZ1066 Na+/H+ antiporter YP_141988.1 1464596 R 299768 CDS YP_141989.1 55823548 3166802 complement(1466671..1466913) 1 NC_006449.1 hypothetical protein 1466913 3166802 str1644 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141989.1 1466671 R 299768 CDS YP_141990.1 55823549 3166801 complement(1466910..1467458) 1 NC_006449.1 rRNA methylase 1467458 3166801 str1645 Streptococcus thermophilus CNRZ1066 rRNA methylase YP_141990.1 1466910 R 299768 CDS YP_141991.1 55823550 3165752 complement(1467455..1468399) 1 NC_006449.1 hypothetical protein 1468399 3165752 str1646 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141991.1 1467455 R 299768 CDS YP_141992.1 55823551 3166796 complement(1468484..1469560) 1 NC_006449.1 protease 1469560 3166796 str1647 Streptococcus thermophilus CNRZ1066 protease YP_141992.1 1468484 R 299768 CDS YP_141993.1 55823552 3166793 complement(1469538..1470035) 1 NC_006449.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1470035 coaD 3166793 coaD Streptococcus thermophilus CNRZ1066 phosphopantetheine adenylyltransferase YP_141993.1 1469538 R 299768 CDS YP_141994.1 55823553 3165718 complement(1470069..1470668) 1 NC_006449.1 methyltransferase 1470668 3165718 str1649 Streptococcus thermophilus CNRZ1066 methyltransferase YP_141994.1 1470069 R 299768 CDS YP_141995.1 55823554 3166519 complement(1470759..1471679) 1 NC_006449.1 thioredoxin reductase 1471679 trxB1 3166519 trxB1 Streptococcus thermophilus CNRZ1066 thioredoxin reductase YP_141995.1 1470759 R 299768 CDS YP_141996.1 55823555 3166794 complement(1471745..1471969) 1 NC_006449.1 hypothetical protein 1471969 3166794 str1651 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_141996.1 1471745 R 299768 CDS YP_141997.1 55823556 3165720 complement(1472184..1472927) 1 NC_006449.1 ABC transporter ATP-binding protein, amino acid 1472927 3165720 str1652 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding protein, amino acid YP_141997.1 1472184 R 299768 CDS YP_141998.1 55823557 3166304 complement(1472927..1473784) 1 NC_006449.1 ABC transporter amino acid permease 1473784 3166304 str1653 Streptococcus thermophilus CNRZ1066 ABC transporter amino acid permease YP_141998.1 1472927 R 299768 CDS YP_141999.1 55823558 3166303 complement(1474062..1474913) 1 NC_006449.1 ABC transporter substrate-binding protein, amino acid 1474913 3166303 str1654 Streptococcus thermophilus CNRZ1066 ABC transporter substrate-binding protein, amino acid YP_141999.1 1474062 R 299768 CDS YP_142000.1 55823559 3166112 complement(1475470..1475703) 1 NC_006449.1 hypothetical protein 1475703 3166112 str1655 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142000.1 1475470 R 299768 CDS YP_142001.1 55823560 3166765 complement(1475989..1477092) 1 NC_006449.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1477092 dinP 3166765 dinP Streptococcus thermophilus CNRZ1066 DNA polymerase IV YP_142001.1 1475989 R 299768 CDS YP_142002.1 55823561 3166764 1477370..1479679 1 NC_006449.1 pyruvate formate-lyase 1479679 pfl 3166764 pfl Streptococcus thermophilus CNRZ1066 pyruvate formate-lyase YP_142002.1 1477370 D 299768 CDS YP_142003.1 55823562 3166629 1479946..1480608 1 NC_006449.1 carbonate dehydratase 1480608 cah 3166629 cah Streptococcus thermophilus CNRZ1066 carbonate dehydratase YP_142003.1 1479946 D 299768 CDS YP_142004.1 55823563 3166795 1480779..1481045 1 NC_006449.1 hypothetical protein 1481045 3166795 str1659 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142004.1 1480779 D 299768 CDS YP_142005.1 55823564 3166340 complement(1481566..1481889) 1 NC_006449.1 truncated; type I restriction-modification system specificty subunit, truncated 1481889 3166340 str1660 Streptococcus thermophilus CNRZ1066 type I restriction-modification system specificty subunit, truncated YP_142005.1 1481566 R 299768 CDS YP_142006.1 55823565 3165944 complement(1482207..1482425) 1 NC_006449.1 truncated; plasmid mobilization protein, truncated 1482425 3165944 str1662 Streptococcus thermophilus CNRZ1066 plasmid mobilization protein, truncated YP_142006.1 1482207 R 299768 CDS YP_142007.1 55823566 3166149 complement(1482902..1483363) 1 NC_006449.1 integrase/recombinase plasmid associated 1483363 int3 3166149 int3 Streptococcus thermophilus CNRZ1066 integrase/recombinase plasmid associated YP_142007.1 1482902 R 299768 CDS YP_142008.1 55823567 3166306 complement(1483584..1484270) 1 NC_006449.1 hypothetical protein 1484270 3166306 str1664 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142008.1 1483584 R 299768 CDS YP_142009.1 55823568 3166230 complement(1484346..1485101) 1 NC_006449.1 hypothetical protein 1485101 3166230 str1665 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142009.1 1484346 R 299768 CDS YP_142010.1 55823569 3165750 complement(1485098..1485748) 1 NC_006449.1 ABC transporter ATP binding protein 1485748 3165750 str1666 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein YP_142010.1 1485098 R 299768 CDS YP_142011.1 55823570 3165948 complement(1485950..1486921) 1 NC_006449.1 hypothetical protein 1486921 3165948 str1667 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142011.1 1485950 R 299768 CDS YP_142012.1 55823571 3166602 complement(1486906..1487673) 1 NC_006449.1 C3-degrading proteinase 1487673 cppA 3166602 cppA Streptococcus thermophilus CNRZ1066 C3-degrading proteinase YP_142012.1 1486906 R 299768 CDS YP_142013.1 55823572 3165953 1487969..1488967 1 NC_006449.1 IS1239 transposase 1488967 tnp1239 3165953 tnp1239 Streptococcus thermophilus CNRZ1066 IS1239 transposase YP_142013.1 1487969 D 299768 CDS YP_142014.1 55823573 3165942 1489077..1489463 1 NC_006449.1 hypothetical protein 1489463 3165942 str1670 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142014.1 1489077 D 299768 CDS YP_142015.1 55823574 3166775 complement(1489637..1490500) 1 NC_006449.1 glycerol uptake facilitator protein 1490500 gla 3166775 gla Streptococcus thermophilus CNRZ1066 glycerol uptake facilitator protein YP_142015.1 1489637 R 299768 CDS YP_142016.1 55823575 3166345 1490621..1492888 1 NC_006449.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1492888 pepXP 3166345 pepXP Streptococcus thermophilus CNRZ1066 x-prolyl-dipeptidyl aminopeptidase YP_142016.1 1490621 D 299768 CDS YP_142017.1 55823576 3165994 complement(1492968..1493312) 1 NC_006449.1 truncated; bacteriocin self-immunity protein , truncated 1493312 3165994 str1673 Streptococcus thermophilus CNRZ1066 bacteriocin self-immunity protein , truncated YP_142017.1 1492968 R 299768 CDS YP_142018.1 55823577 3165801 1493304..1493837 1 NC_006449.1 truncated; hypothetical protein 1493837 3165801 str1677 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142018.1 1493304 D 299768 CDS YP_142019.1 55823578 3166668 1493852..1494721 1 NC_006449.1 IS3 familytransposase orf2 1494721 tnpSth1 3166668 tnpSth1 Streptococcus thermophilus CNRZ1066 IS3 familytransposase orf2 YP_142019.1 1493852 D 299768 CDS YP_142020.1 55823579 3166551 complement(1494867..1495109) 1 NC_006449.1 pore-forming peptide bacteriocin 1495109 blpK 3166551 blpK Streptococcus thermophilus CNRZ1066 pore-forming peptide bacteriocin YP_142020.1 1494867 R 299768 CDS YP_142021.1 55823580 3165903 1495359..1496090 1 NC_006449.1 response regulator 1496090 rr09 3165903 rr09 Streptococcus thermophilus CNRZ1066 response regulator YP_142021.1 1495359 D 299768 CDS YP_142022.1 55823581 3166077 1496090..1497430 1 NC_006449.1 sensor histidine kinase BlpH-like protein 1497430 hk09 3166077 hk09 Streptococcus thermophilus CNRZ1066 sensor histidine kinase BlpH-like protein YP_142022.1 1496090 D 299768 CDS YP_142023.1 55823582 3166403 complement(1497448..1497609) 1 NC_006449.1 signal peptide 1497609 blpC 3166403 blpC Streptococcus thermophilus CNRZ1066 signal peptide YP_142023.1 1497448 R 299768 CDS YP_142024.1 55823583 3166191 complement(1497624..1498529) 1 NC_006449.1 truncated; peptide ABC transporter 1498529 3166191 str1689 Streptococcus thermophilus CNRZ1066 peptide ABC transporter YP_142024.1 1497624 R 299768 CDS YP_142025.1 55823584 3166373 complement(1498657..1498992) 1 NC_006449.1 truncated; peptide ABC transporter 1498992 3166373 str1690 Streptococcus thermophilus CNRZ1066 peptide ABC transporter YP_142025.1 1498657 R 299768 CDS YP_142026.1 55823585 3166464 complement(1499008..1501176) 1 NC_006449.1 peptide ABC transporter ATP-binding protein/permease 1501176 blpA 3166464 blpA Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein/permease YP_142026.1 1499008 R 299768 CDS YP_142027.1 55823586 3166779 1501596..1501847 1 NC_006449.1 hypothetical protein 1501847 3166779 str1692 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142027.1 1501596 D 299768 CDS YP_142028.1 55823587 3166082 complement(1502175..1503920) 1 NC_006449.1 ABC transporter ATP-binding/permease 1503920 3166082 str1693 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding/permease YP_142028.1 1502175 R 299768 CDS YP_142029.1 55823588 3165906 complement(1503913..1505670) 1 NC_006449.1 ABC transporter ATP-binding/permease 1505670 3165906 str1694 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding/permease YP_142029.1 1503913 R 299768 CDS YP_142030.1 55823589 3166320 complement(1506269..1506796) 1 NC_006449.1 region, VanZF-like 1506796 3166320 str1695 Streptococcus thermophilus CNRZ1066 region, VanZF-like YP_142030.1 1506269 R 299768 CDS YP_142031.1 55823590 3166648 complement(1506798..1507967) 1 NC_006449.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1507967 3166648 str1696 Streptococcus thermophilus CNRZ1066 ribosomal RNA large subunit methyltransferase N YP_142031.1 1506798 R 299768 CDS YP_142032.1 55823591 3166595 complement(1507971..1508693) 1 NC_006449.1 hypothetical protein 1508693 3166595 str1697 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142032.1 1507971 R 299768 CDS YP_142033.1 55823592 3166746 complement(1508748..1510103) 1 NC_006449.1 hypothetical protein 1510103 3166746 str1698 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142033.1 1508748 R 299768 CDS YP_142034.1 55823593 3166350 complement(1510951..1512294) 1 NC_006449.1 ATP-dependent RNA helicase 1512294 rheB 3166350 rheB Streptococcus thermophilus CNRZ1066 ATP-dependent RNA helicase YP_142034.1 1510951 R 299768 CDS YP_142035.1 55823594 3166671 complement(1512369..1513391) 1 NC_006449.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1513391 mraY 3166671 mraY Streptococcus thermophilus CNRZ1066 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_142035.1 1512369 R 299768 CDS YP_142036.1 55823595 3166202 complement(1513393..1515660) 1 NC_006449.1 penicillin binding protein 2X 1515660 pbp2X 3166202 pbp2X Streptococcus thermophilus CNRZ1066 penicillin binding protein 2X YP_142036.1 1513393 R 299768 CDS YP_142037.1 55823596 3166493 complement(1515664..1515984) 1 NC_006449.1 cell division protein 1515984 ftsL 3166493 ftsL Streptococcus thermophilus CNRZ1066 cell division protein YP_142037.1 1515664 R 299768 CDS YP_142038.1 55823597 3165912 complement(1515987..1517051) 1 NC_006449.1 S-adenosyl-methyltransferase MraW 1517051 mraW 3165912 mraW Streptococcus thermophilus CNRZ1066 S-adenosyl-methyltransferase MraW YP_142038.1 1515987 R 299768 CDS YP_142039.1 55823598 3166227 complement(1517105..1517455) 1 NC_006449.1 hypothetical protein 1517455 3166227 str1704 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142039.1 1517105 R 299768 CDS YP_142040.1 55823599 3166095 complement(1517552..1517758) 1 NC_006449.1 hypothetical protein 1517758 3166095 str1705 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142040.1 1517552 R 299768 CDS YP_142041.1 55823600 3166513 complement(1517713..1518213) 1 NC_006449.1 hypothetical protein 1518213 3166513 str1706 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142041.1 1517713 R 299768 CDS YP_142042.1 55823601 3166533 complement(1518210..1518464) 1 NC_006449.1 hypothetical protein 1518464 3166533 str1707 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142042.1 1518210 R 299768 CDS YP_142043.1 55823602 3166228 complement(1518738..1519094) 1 NC_006449.1 hypothetical protein 1519094 3166228 str1708 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142043.1 1518738 R 299768 CDS YP_142044.1 55823603 3166123 complement(1519314..1519550) 1 NC_006449.1 hypothetical protein 1519550 3166123 str1709 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142044.1 1519314 R 299768 CDS YP_142045.1 55823604 3166286 complement(1519963..1521213) 1 NC_006449.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1521213 proA 3166286 proA Streptococcus thermophilus CNRZ1066 gamma-glutamyl phosphate reductase YP_142045.1 1519963 R 299768 CDS YP_142046.1 55823605 3166559 complement(1521215..1522018) 1 NC_006449.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1522018 proB 3166559 proB Streptococcus thermophilus CNRZ1066 gamma-glutamyl kinase YP_142046.1 1521215 R 299768 CDS YP_142047.1 55823606 3165826 complement(1522139..1523728) 1 NC_006449.1 hypothetical protein 1523728 3165826 str1712 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142047.1 1522139 R 299768 CDS YP_142048.1 55823607 3166046 complement(1523731..1524231) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1524231 3166046 str1713 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_142048.1 1523731 R 299768 CDS YP_142049.1 55823608 3166289 complement(1524185..1524463) 1 NC_006449.1 truncated; ABC transporter ATP binding protein, truncated 1524463 3166289 str1714 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding protein, truncated YP_142049.1 1524185 R 299768 CDS YP_142050.1 55823609 3166537 1524737..1525366 1 NC_006449.1 hypothetical protein 1525366 3166537 str1715 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142050.1 1524737 D 299768 CDS YP_142051.1 55823610 3166404 complement(1525864..1529517) 1 NC_006449.1 ATP-dependent exonuclease subunit A 1529517 rexA 3166404 rexA Streptococcus thermophilus CNRZ1066 ATP-dependent exonuclease subunit A YP_142051.1 1525864 R 299768 CDS YP_142052.1 55823611 3166038 complement(1529507..1532827) 1 NC_006449.1 ATP-dependent exonuclease subunit B 1532827 rexB 3166038 rexB Streptococcus thermophilus CNRZ1066 ATP-dependent exonuclease subunit B YP_142052.1 1529507 R 299768 CDS YP_142053.1 55823612 3166240 complement(1533516..1533968) 1 NC_006449.1 hypothetical protein 1533968 3166240 str1718 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142053.1 1533516 R 299768 CDS YP_142054.1 55823613 3166239 complement(1534311..1534451) 1 NC_006449.1 hypothetical protein 1534451 3166239 str1719 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142054.1 1534311 R 299768 CDS YP_142055.1 55823614 3166005 complement(1534669..1535187) 1 NC_006449.1 hypothetical protein 1535187 3166005 str1720 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142055.1 1534669 R 299768 CDS YP_142056.1 55823615 3166835 complement(1535750..1536616) 1 NC_006449.1 hypothetical protein 1536616 3166835 str1721 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142056.1 1535750 R 299768 CDS YP_142057.1 55823616 3166654 complement(1536891..1538276) 1 NC_006449.1 hypothetical protein 1538276 3166654 str1723 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142057.1 1536891 R 299768 CDS YP_142058.1 55823617 3166477 1538347..1539315 1 NC_006449.1 L-asparaginase 1539315 ansB 3166477 ansB Streptococcus thermophilus CNRZ1066 L-asparaginase YP_142058.1 1538347 D 299768 CDS YP_142059.1 55823618 3166488 complement(1540084..1542102) 1 NC_006449.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1542102 recG 3166488 recG Streptococcus thermophilus CNRZ1066 ATP-dependent DNA helicase RecG YP_142059.1 1540084 R 299768 CDS YP_142060.1 55823619 3166241 complement(1542231..1543334) 1 NC_006449.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1543334 alr 3166241 alr Streptococcus thermophilus CNRZ1066 alanine racemase YP_142060.1 1542231 R 299768 CDS YP_142061.1 55823620 3166409 complement(1543355..1543714) 1 NC_006449.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1543714 acpS 3166409 acpS Streptococcus thermophilus CNRZ1066 4'-phosphopantetheinyl transferase YP_142061.1 1543355 R 299768 CDS YP_142062.1 55823621 3166715 complement(1543718..1544749) 1 NC_006449.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1544749 aroG 3166715 aroG Streptococcus thermophilus CNRZ1066 phospho-2-dehydro-3-deoxyheptonate aldolase YP_142062.1 1543718 R 299768 CDS YP_142063.1 55823622 3166517 complement(1544773..1547322) 1 NC_006449.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1547322 secA 3166517 secA Streptococcus thermophilus CNRZ1066 preprotein translocase subunit SecA YP_142063.1 1544773 R 299768 CDS YP_142064.1 55823623 3165685 complement(1547505..1547765) 1 NC_006449.1 hypothetical protein 1547765 3165685 str1731 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142064.1 1547505 R 299768 CDS YP_142065.1 55823624 3165951 complement(1547852..1548799) 1 NC_006449.1 mannose-6-phosphate isomerase 1548799 pmi1 3165951 pmi1 Streptococcus thermophilus CNRZ1066 mannose-6-phosphate isomerase YP_142065.1 1547852 R 299768 CDS YP_142066.1 55823625 3165679 complement(1548865..1549758) 1 NC_006449.1 fructokinase 1549758 scrK 3165679 scrK Streptococcus thermophilus CNRZ1066 fructokinase YP_142066.1 1548865 R 299768 CDS YP_142067.1 55823626 3166162 complement(1549943..1551850) 1 NC_006449.1 PTS system sucrose-specific transporter subunit II 1551850 scrA 3166162 scrA Streptococcus thermophilus CNRZ1066 PTS system sucrose-specific transporter subunit II YP_142067.1 1549943 R 299768 CDS YP_142068.1 55823627 3166116 1552093..1553535 1 NC_006449.1 sucrose-6-phosphate hydrolase 1553535 scrB 3166116 scrB Streptococcus thermophilus CNRZ1066 sucrose-6-phosphate hydrolase YP_142068.1 1552093 D 299768 CDS YP_142069.1 55823628 3165882 1553544..1553774 1 NC_006449.1 truncated; sucrose regulon regulatory protein, truncated 1553774 3165882 str1736 Streptococcus thermophilus CNRZ1066 sucrose regulon regulatory protein, truncated YP_142069.1 1553544 D 299768 CDS YP_142070.1 55823629 3166099 1553869..1554510 1 NC_006449.1 truncated; sucrose regulon regulatory protein, truncated 1554510 3166099 str1737 Streptococcus thermophilus CNRZ1066 sucrose regulon regulatory protein, truncated YP_142070.1 1553869 D 299768 CDS YP_142071.1 55823630 3166484 complement(1554600..1555034) 1 NC_006449.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1555034 nusB 3166484 nusB Streptococcus thermophilus CNRZ1066 transcription antitermination protein NusB YP_142071.1 1554600 R 299768 CDS YP_142072.1 55823631 3166606 complement(1555027..1555458) 1 NC_006449.1 hypothetical protein 1555458 3166606 str1739 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142072.1 1555027 R 299768 CDS YP_142073.1 55823632 3166762 complement(1555487..1556047) 1 NC_006449.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1556047 efp 3166762 efp Streptococcus thermophilus CNRZ1066 elongation factor P YP_142073.1 1555487 R 299768 CDS YP_142074.1 55823633 3166505 complement(1556160..1556630) 1 NC_006449.1 late competence protein required for DNA binding and uptake 1556630 comEB 3166505 comEB Streptococcus thermophilus CNRZ1066 late competence protein required for DNA binding and uptake YP_142074.1 1556160 R 299768 CDS YP_142075.1 55823634 3166747 complement(1556634..1557695) 1 NC_006449.1 aminopeptidase 1557695 pepP 3166747 pepP Streptococcus thermophilus CNRZ1066 aminopeptidase YP_142075.1 1556634 R 299768 CDS YP_142076.1 55823635 3166015 complement(1557884..1558312) 1 NC_006449.1 hypothetical protein 1558312 3166015 str1743 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142076.1 1557884 R 299768 CDS YP_142077.1 55823636 3166568 complement(1558539..1558958) 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein 1558958 3166568 str1744 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein YP_142077.1 1558539 R 299768 CDS YP_142078.1 55823637 3165930 complement(1558918..1559154) 1 NC_006449.1 truncated; peptide ABC transporter ATP-binding protein 1559154 3165930 str1745 Streptococcus thermophilus CNRZ1066 peptide ABC transporter ATP-binding protein YP_142078.1 1558918 R 299768 CDS YP_142079.1 55823638 3165806 complement(1559494..1559685) 1 NC_006449.1 hypothetical protein 1559685 3165806 str1746 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142079.1 1559494 R 299768 CDS YP_142080.1 55823639 3165876 complement(1559847..1560119) 1 NC_006449.1 hypothetical protein 1560119 3165876 str1747 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142080.1 1559847 R 299768 CDS YP_142081.1 55823640 3166412 complement(1560213..1563038) 1 NC_006449.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1563038 uvrA 3166412 uvrA Streptococcus thermophilus CNRZ1066 excinuclease ABC subunit A YP_142081.1 1560213 R 299768 CDS YP_142082.1 55823641 3166260 1563347..1564291 1 NC_006449.1 cation transporter 1564291 corA2 3166260 corA2 Streptococcus thermophilus CNRZ1066 cation transporter YP_142082.1 1563347 D 299768 CDS YP_142083.1 55823642 3165642 1564362..1565033 1 NC_006449.1 hypothetical protein 1565033 3165642 str1750 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142083.1 1564362 D 299768 CDS YP_142084.1 55823643 3166276 1565150..1566031 1 NC_006449.1 hypothetical protein 1566031 3166276 str1751 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142084.1 1565150 D 299768 CDS YP_142085.1 55823644 3166782 complement(1566158..1566397) 1 NC_006449.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1566397 rpsR 3166782 rpsR Streptococcus thermophilus CNRZ1066 30S ribosomal protein S18 YP_142085.1 1566158 R 299768 CDS YP_142086.1 55823645 3165884 complement(1566439..1566957) 1 NC_006449.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1566957 ssbB 3165884 ssbB Streptococcus thermophilus CNRZ1066 single-stranded DNA-binding protein YP_142086.1 1566439 R 299768 CDS YP_142087.2 161936363 3166547 complement(1566969..1567259) 1 NC_006449.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1567259 rpsF 3166547 rpsF Streptococcus thermophilus CNRZ1066 30S ribosomal protein S6 YP_142087.2 1566969 R 299768 CDS YP_142088.1 55823647 3165663 1567478..1567810 1 NC_006449.1 hypothetical protein 1567810 3165663 str1755 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142088.1 1567478 D 299768 CDS YP_142089.1 55823648 3166310 1567848..1568432 1 NC_006449.1 hypothetical protein 1568432 3166310 str1756 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142089.1 1567848 D 299768 CDS YP_142090.1 55823649 3166740 1569097..1570248 1 NC_006449.1 A/G-specific adenine glycosylase 1570248 mutY 3166740 mutY Streptococcus thermophilus CNRZ1066 A/G-specific adenine glycosylase YP_142090.1 1569097 D 299768 CDS YP_142091.1 55823650 3166501 complement(1570575..1570826) 1 NC_006449.1 hypothetical protein 1570826 3166501 str1758 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142091.1 1570575 R 299768 CDS YP_142092.1 55823651 3166582 complement(1570929..1571141) 1 NC_006449.1 hypothetical protein 1571141 3166582 str1759 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142092.1 1570929 R 299768 CDS YP_142093.1 55823652 3166778 complement(1571144..1571488) 1 NC_006449.1 hypothetical protein 1571488 3166778 str1760 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142093.1 1571144 R 299768 CDS YP_142094.1 55823653 3165746 complement(1572077..1574716) 1 NC_006449.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1574716 polA 3165746 polA Streptococcus thermophilus CNRZ1066 DNA polymerase I YP_142094.1 1572077 R 299768 CDS YP_142095.1 55823654 3165699 1574923..1577274 1 NC_006449.1 DNA mismatch repair protein 1577274 mutS2 3165699 mutS2 Streptococcus thermophilus CNRZ1066 DNA mismatch repair protein YP_142095.1 1574923 D 299768 CDS YP_142096.1 55823655 3165691 complement(1577375..1577917) 1 NC_006449.1 hypothetical protein 1577917 3165691 str1763 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142096.1 1577375 R 299768 CDS YP_142097.1 55823656 3165677 complement(1577914..1578231) 1 NC_006449.1 hypothetical protein 1578231 3165677 str1764 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142097.1 1577914 R 299768 CDS YP_142098.1 55823657 3165897 1578545..1579435 1 NC_006449.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1579435 rnhB 3165897 rnhB Streptococcus thermophilus CNRZ1066 ribonuclease HIII YP_142098.1 1578545 D 299768 CDS YP_142099.1 55823658 3165831 1579454..1580077 1 NC_006449.1 signal peptidase I 1580077 sipA 3165831 sipA Streptococcus thermophilus CNRZ1066 signal peptidase I YP_142099.1 1579454 D 299768 CDS YP_142100.1 55823659 3165887 1580139..1582643 1 NC_006449.1 exodeoxyribonuclease V 1582643 recD 3165887 recD Streptococcus thermophilus CNRZ1066 exodeoxyribonuclease V YP_142100.1 1580139 D 299768 CDS YP_142101.1 55823660 3166067 complement(1582699..1583025) 1 NC_006449.1 hypothetical protein 1583025 3166067 str1768 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142101.1 1582699 R 299768 CDS YP_142102.1 55823661 3166104 complement(1583012..1583710) 1 NC_006449.1 amino acid permease 1583710 3166104 str1769 Streptococcus thermophilus CNRZ1066 amino acid permease YP_142102.1 1583012 R 299768 CDS YP_142103.1 55823662 3166382 complement(1583756..1584769) 1 NC_006449.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1584769 gcp 3166382 gcp Streptococcus thermophilus CNRZ1066 DNA-binding/iron metalloprotein/AP endonuclease YP_142103.1 1583756 R 299768 CDS YP_142104.1 55823663 3166100 complement(1584769..1585224) 1 NC_006449.1 ribosomal-protein-alanine acetyltransferase 1585224 rimI 3166100 rimI Streptococcus thermophilus CNRZ1066 ribosomal-protein-alanine acetyltransferase YP_142104.1 1584769 R 299768 CDS YP_142105.1 55823664 3166031 complement(1585184..1585945) 1 NC_006449.1 glycoprotein endopeptidase 1585945 3166031 str1772 Streptococcus thermophilus CNRZ1066 glycoprotein endopeptidase YP_142105.1 1585184 R 299768 CDS YP_142106.1 55823665 3166180 1586133..1586363 1 NC_006449.1 hypothetical protein 1586363 3166180 str1773 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142106.1 1586133 D 299768 CDS YP_142107.1 55823666 3166041 1586368..1588050 1 NC_006449.1 metallo-beta-lactamase superfamily protein 1588050 3166041 str1774 Streptococcus thermophilus CNRZ1066 metallo-beta-lactamase superfamily protein YP_142107.1 1586368 D 299768 CDS YP_142108.1 55823667 3166212 complement(1588286..1588465) 1 NC_006449.1 glucan-binding protein 1588465 3166212 str1775 Streptococcus thermophilus CNRZ1066 glucan-binding protein YP_142108.1 1588286 R 299768 CDS YP_142109.1 55823668 3166115 complement(1588876..1590246) 1 NC_006449.1 glutamine synthetase 1590246 gnlA 3166115 gnlA Streptococcus thermophilus CNRZ1066 glutamine synthetase YP_142109.1 1588876 R 299768 CDS YP_142110.1 55823669 3166203 complement(1590268..1590642) 1 NC_006449.1 glutamine synthetase transcriptional regulatorMerR family 1590642 gnlR 3166203 gnlR Streptococcus thermophilus CNRZ1066 glutamine synthetase transcriptional regulatorMerR family YP_142110.1 1590268 R 299768 CDS YP_142111.1 55823670 3166496 complement(1590816..1591319) 1 NC_006449.1 hypothetical protein 1591319 3166496 str1778 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142111.1 1590816 R 299768 CDS YP_142112.1 55823671 3166130 1591562..1591906 1 NC_006449.1 truncated; truncated IS1193 transposase 1591906 3166130 str1779 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_142112.1 1591562 D 299768 CDS YP_142113.1 55823672 3166052 1592211..1592381 1 NC_006449.1 truncated; truncated IS1193 transposase 1592381 3166052 str1781 Streptococcus thermophilus CNRZ1066 truncated IS1193 transposase YP_142113.1 1592211 D 299768 CDS YP_142114.1 55823673 3166324 complement(1592454..1593653) 1 NC_006449.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1593653 pgk 3166324 pgk Streptococcus thermophilus CNRZ1066 phosphoglycerate kinase YP_142114.1 1592454 R 299768 CDS YP_142115.1 55823674 3166218 complement(1593906..1594154) 1 NC_006449.1 truncated; hypothetical protein 1594154 3166218 str1783 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142115.1 1593906 R 299768 CDS YP_142116.1 55823675 3166510 1594269..1594553 1 NC_006449.1 truncated; hypothetical protein 1594553 3166510 str1784 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142116.1 1594269 D 299768 CDS YP_142117.1 55823676 3166105 1594615..1594830 1 NC_006449.1 truncated; hypothetical protein 1594830 3166105 str1785 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142117.1 1594615 D 299768 CDS YP_142118.1 55823677 3166469 1594779..1595117 1 NC_006449.1 truncated; hypothetical protein 1595117 3166469 str1786 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142118.1 1594779 D 299768 CDS YP_142119.1 55823678 3166462 1595131..1595619 1 NC_006449.1 truncated; hypothetical protein 1595619 3166462 str1787 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142119.1 1595131 D 299768 CDS YP_142120.1 55823679 3166653 complement(1595768..1596805) 1 NC_006449.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1596805 gapA1 3166653 gapA1 Streptococcus thermophilus CNRZ1066 glyceraldehyde-3-phosphate dehydrogenase YP_142120.1 1595768 R 299768 CDS YP_142121.1 55823680 3166509 complement(1596965..1599046) 1 NC_006449.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1599046 fus 3166509 fus Streptococcus thermophilus CNRZ1066 elongation factor G YP_142121.1 1596965 R 299768 CDS YP_142122.1 55823681 3166486 complement(1599267..1599737) 1 NC_006449.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1599737 rpsG 3166486 rpsG Streptococcus thermophilus CNRZ1066 30S ribosomal protein S7 YP_142122.1 1599267 R 299768 CDS YP_142123.1 55823682 3166528 complement(1599756..1600169) 1 NC_006449.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1600169 rpsL 3166528 rpsL Streptococcus thermophilus CNRZ1066 30S ribosomal protein S12 YP_142123.1 1599756 R 299768 CDS YP_142124.1 55823683 3166614 complement(1600385..1601209) 1 NC_006449.1 pur operon repressor 1601209 purR 3166614 purR Streptococcus thermophilus CNRZ1066 pur operon repressor YP_142124.1 1600385 R 299768 CDS YP_142125.1 55823684 3167528 complement(1601303..1602256) 1 NC_006449.1 CMP-binding factor 1602256 cbf 3167528 cbf Streptococcus thermophilus CNRZ1066 CMP-binding factor YP_142125.1 1601303 R 299768 CDS YP_142126.1 55823685 3167532 complement(1602234..1603508) 1 NC_006449.1 hypothetical protein 1603508 3167532 str1795 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142126.1 1602234 R 299768 CDS YP_142127.1 55823686 3166615 complement(1603510..1604142) 1 NC_006449.1 hypothetical protein 1604142 3166615 str1796 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142127.1 1603510 R 299768 CDS YP_142128.1 55823687 3167533 complement(1604135..1604854) 1 NC_006449.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1604854 rpe 3167533 rpe Streptococcus thermophilus CNRZ1066 ribulose-phosphate 3-epimerase YP_142128.1 1604135 R 299768 CDS YP_142129.1 55823688 3167531 complement(1604802..1605674) 1 NC_006449.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1605674 3167531 str1798 Streptococcus thermophilus CNRZ1066 ribosome-associated GTPase YP_142129.1 1604802 R 299768 CDS YP_142130.1 55823689 3166716 complement(1605931..1606803) 1 NC_006449.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1606803 ksgA 3166716 ksgA Streptococcus thermophilus CNRZ1066 dimethyladenosine transferase YP_142130.1 1605931 R 299768 CDS YP_142131.1 55823690 3166682 complement(1606948..1607508) 1 NC_006449.1 topoisomerase/primase 1607508 3166682 str1800 Streptococcus thermophilus CNRZ1066 topoisomerase/primase YP_142131.1 1606948 R 299768 CDS YP_142132.1 55823691 3166646 complement(1607501..1608277) 1 NC_006449.1 deoxyribonuclease 1608277 tatD 3166646 tatD Streptococcus thermophilus CNRZ1066 deoxyribonuclease YP_142132.1 1607501 R 299768 CDS YP_142133.1 55823692 3167530 complement(1608331..1608783) 1 NC_006449.1 hypothetical protein 1608783 3167530 str1802 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142133.1 1608331 R 299768 CDS YP_142134.1 55823693 3166360 complement(1608822..1609136) 1 NC_006449.1 thioredoxin 1609136 trxA1 3166360 trxA1 Streptococcus thermophilus CNRZ1066 thioredoxin YP_142134.1 1608822 R 299768 CDS YP_142135.1 55823694 3166506 1609332..1610114 1 NC_006449.1 hypothetical protein 1610114 3166506 str1804 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142135.1 1609332 D 299768 CDS YP_142136.1 55823695 3166169 complement(1610575..1610910) 1 NC_006449.1 bacteriocin transport accessory protein 1610910 bta 3166169 bta Streptococcus thermophilus CNRZ1066 bacteriocin transport accessory protein YP_142136.1 1610575 R 299768 CDS YP_142137.1 55823696 3166435 complement(1616734..1617876) 1 NC_006449.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1617876 tgt 3166435 tgt Streptococcus thermophilus CNRZ1066 queuine tRNA-ribosyltransferase YP_142137.1 1616734 R 299768 CDS YP_142138.1 55823697 3166431 complement(1618129..1618602) 1 NC_006449.1 IS200 family transposase 1618602 tnp657 3166431 tnp657 Streptococcus thermophilus CNRZ1066 IS200 family transposase YP_142138.1 1618129 R 299768 CDS YP_142139.1 55823698 3166489 complement(1618780..1618914) 1 NC_006449.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1618914 rpmH 3166489 rpmH Streptococcus thermophilus CNRZ1066 50S ribosomal protein L34 YP_142139.1 1618780 R 299768 CDS YP_142140.1 55823699 3166833 complement(1619801..1620850) 1 NC_006449.1 DNA/RNA-binding protein 1620850 jag 3166833 jag Streptococcus thermophilus CNRZ1066 DNA/RNA-binding protein YP_142140.1 1619801 R 299768 CDS YP_142141.1 55823700 3166825 complement(1620862..1621668) 1 NC_006449.1 hypothetical protein 1621668 3166825 str1810 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142141.1 1620862 R 299768 CDS YP_142142.1 55823701 3167527 complement(1621783..1622118) 1 NC_006449.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1622118 rnpA 3167527 rnpA Streptococcus thermophilus CNRZ1066 ribonuclease P YP_142142.1 1621783 R 299768 CDS YP_142143.1 55823702 3166978 complement(1622203..1623678) 1 NC_006449.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1623678 argH 3166978 argH Streptococcus thermophilus CNRZ1066 argininosuccinate lyase YP_142143.1 1622203 R 299768 CDS YP_142144.2 161936362 3167039 complement(1623917..1625116) 1 NC_006449.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 1625116 argG 3167039 argG Streptococcus thermophilus CNRZ1066 argininosuccinate synthase YP_142144.2 1623917 R 299768 CDS YP_142145.1 55823704 3167194 complement(1626019..1627473) 1 NC_006449.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1627473 gltX 3167194 gltX Streptococcus thermophilus CNRZ1066 glutamyl-tRNA synthetase YP_142145.1 1626019 R 299768 CDS YP_142146.1 55823705 3166844 complement(1627814..1628287) 1 NC_006449.1 truncated; oligopeptide ABC transporter substrate-binding protein, truncated 1628287 3166844 str1815 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein, truncated YP_142146.1 1627814 R 299768 CDS YP_142147.1 55823706 3165921 complement(1628284..1628709) 1 NC_006449.1 truncated; oligopeptide ABC transporter substrate-binding protein, truncated 1628709 3165921 str1816 Streptococcus thermophilus CNRZ1066 oligopeptide ABC transporter substrate-binding protein, truncated YP_142147.1 1628284 R 299768 CDS YP_142148.2 161936361 3166837 complement(1628801..1629490) 1 NC_006449.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1629490 rplA 3166837 rplA Streptococcus thermophilus CNRZ1066 50S ribosomal protein L1 YP_142148.2 1628801 R 299768 CDS YP_142149.1 55823708 3166344 complement(1629590..1630015) 1 NC_006449.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1630015 rplK 3166344 rplK Streptococcus thermophilus CNRZ1066 50S ribosomal protein L11 YP_142149.1 1629590 R 299768 CDS YP_142150.1 55823709 3166860 1630187..1630540 1 NC_006449.1 hypothetical protein 1630540 3166860 str1819 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142150.1 1630187 D 299768 CDS YP_142151.1 55823710 3165670 complement(1630632..1631129) 1 NC_006449.1 hypothetical protein 1631129 3165670 str1820 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142151.1 1630632 R 299768 CDS YP_142152.1 55823711 3166696 complement(1631297..1631497) 1 NC_006449.1 truncated; hypothetical protein 1631497 3166696 str1821 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142152.1 1631297 R 299768 CDS YP_142153.1 55823712 3166428 complement(1631491..1631721) 1 NC_006449.1 truncated; hypothetical protein 1631721 3166428 str1822 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142153.1 1631491 R 299768 CDS YP_142154.1 55823713 3166995 complement(1632061..1633308) 1 NC_006449.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1633308 radA 3166995 radA Streptococcus thermophilus CNRZ1066 DNA repair protein RadA YP_142154.1 1632061 R 299768 CDS YP_142155.1 55823714 3165639 complement(1633600..1634046) 1 NC_006449.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1634046 dut 3165639 dut Streptococcus thermophilus CNRZ1066 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_142155.1 1633600 R 299768 CDS YP_142156.1 55823715 3167524 1634224..1634640 1 NC_006449.1 truncated; oxidoreductase , truncated 1634640 3167524 str1825 Streptococcus thermophilus CNRZ1066 oxidoreductase , truncated YP_142156.1 1634224 D 299768 CDS YP_142157.1 55823716 3167526 1634637..1634855 1 NC_006449.1 truncated; oxidoreductase , truncated 1634855 3167526 str1826 Streptococcus thermophilus CNRZ1066 oxidoreductase , truncated YP_142157.1 1634637 D 299768 CDS YP_142158.1 55823717 3166349 1634883..1635110 1 NC_006449.1 truncated; oxidoreductase , truncated 1635110 3166349 str1827 Streptococcus thermophilus CNRZ1066 oxidoreductase , truncated YP_142158.1 1634883 D 299768 CDS YP_142159.1 55823718 3166839 1635134..1635853 1 NC_006449.1 truncated; oxidoreductase , truncated 1635853 3166839 str1828 Streptococcus thermophilus CNRZ1066 oxidoreductase , truncated YP_142159.1 1635134 D 299768 CDS YP_142160.1 55823719 3165774 1636060..1636242 1 NC_006449.1 truncated; formate-nitrate transporter, truncated 1636242 3165774 str1829 Streptococcus thermophilus CNRZ1066 formate-nitrate transporter, truncated YP_142160.1 1636060 D 299768 CDS YP_142161.1 55823720 3166691 1636330..1636761 1 NC_006449.1 truncated; formate-nitrate transporter, truncated 1636761 3166691 str1830 Streptococcus thermophilus CNRZ1066 formate-nitrate transporter, truncated YP_142161.1 1636330 D 299768 CDS YP_142162.1 55823721 3166187 1636770..1637225 1 NC_006449.1 hypothetical protein 1637225 3166187 str1831 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142162.1 1636770 D 299768 CDS YP_142163.2 161936360 3167365 1637458..1638480 1 NC_006449.1 NAD(P)+; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1638480 gpsA 3167365 gpsA Streptococcus thermophilus CNRZ1066 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_142163.2 1637458 D 299768 CDS YP_142164.1 55823723 3166172 1638499..1639413 1 NC_006449.1 UDP-glucose pyrophosphorylase 1639413 galU 3166172 galU Streptococcus thermophilus CNRZ1066 UDP-glucose pyrophosphorylase YP_142164.1 1638499 D 299768 CDS YP_142165.1 55823724 3166148 complement(1639459..1640133) 1 NC_006449.1 hypothetical protein 1640133 3166148 str1836 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142165.1 1639459 R 299768 CDS YP_142166.1 55823725 3167517 complement(1640124..1640651) 1 NC_006449.1 hypothetical protein 1640651 3167517 str1837 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142166.1 1640124 R 299768 CDS YP_142167.1 55823726 3167523 complement(1640720..1641853) 1 NC_006449.1 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 1641853 hipO3 3167523 hipO3 Streptococcus thermophilus CNRZ1066 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_142167.1 1640720 R 299768 CDS YP_142168.1 55823727 3166356 complement(1641932..1642630) 1 NC_006449.1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1642630 dapD 3166356 dapD Streptococcus thermophilus CNRZ1066 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_142168.1 1641932 R 299768 CDS YP_142169.1 55823728 3167525 complement(1642716..1643120) 1 NC_006449.1 truncated; hypothetical protein 1643120 3167525 str1840 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142169.1 1642716 R 299768 CDS YP_142170.1 55823729 3166256 complement(1643114..1643485) 1 NC_006449.1 truncated; hypothetical protein 1643485 3166256 str1841 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142170.1 1643114 R 299768 CDS YP_142171.1 55823730 3166808 complement(1643585..1644418) 1 NC_006449.1 rRNA (guanine-N1-)-methyltransferase 1644418 rrmA 3166808 rrmA Streptococcus thermophilus CNRZ1066 rRNA (guanine-N1-)-methyltransferase YP_142171.1 1643585 R 299768 CDS YP_142172.1 55823731 3167515 1644787..1644954 1 NC_006449.1 hypothetical protein 1644954 3167515 str1843 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142172.1 1644787 D 299768 CDS YP_142173.1 55823732 3166511 complement(1645351..1645869) 1 NC_006449.1 cytidine/deoxycytidylate deaminase family protein 1645869 3166511 str1844 Streptococcus thermophilus CNRZ1066 cytidine/deoxycytidylate deaminase family protein YP_142173.1 1645351 R 299768 CDS YP_142174.1 55823733 3167519 complement(1646629..1647021) 1 NC_006449.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1647021 ssbA 3167519 ssbA Streptococcus thermophilus CNRZ1066 single-stranded DNA-binding protein YP_142174.1 1646629 R 299768 CDS YP_142175.1 55823734 3165731 complement(1647226..1647453) 1 NC_006449.1 transcription regulator 1647453 3165731 str1846 Streptococcus thermophilus CNRZ1066 transcription regulator YP_142175.1 1647226 R 299768 CDS YP_142176.1 55823735 3166881 complement(1647468..1648499) 1 NC_006449.1 permease 1648499 3166881 str1847 Streptococcus thermophilus CNRZ1066 permease YP_142176.1 1647468 R 299768 CDS YP_142177.1 55823736 3166520 complement(1648637..1649260) 1 NC_006449.1 phenylalanyl-tRNA synthetase-like protein 1649260 3166520 str1848 Streptococcus thermophilus CNRZ1066 phenylalanyl-tRNA synthetase-like protein YP_142177.1 1648637 R 299768 CDS YP_142178.1 55823737 3165749 complement(1649270..1649584) 1 NC_006449.1 thioredoxin 1649584 trxA2 3165749 trxA2 Streptococcus thermophilus CNRZ1066 thioredoxin YP_142178.1 1649270 R 299768 CDS YP_142179.1 55823738 3167516 complement(1649581..1649874) 1 NC_006449.1 hypothetical protein 1649874 3167516 str1850 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142179.1 1649581 R 299768 CDS YP_142180.1 55823739 3167518 1649965..1651032 1 NC_006449.1 glutamyl-aminopeptidase 1651032 pepA 3167518 pepA Streptococcus thermophilus CNRZ1066 glutamyl-aminopeptidase YP_142180.1 1649965 D 299768 CDS YP_142181.1 55823740 3167522 1651048..1651818 1 NC_006449.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1651818 proC 3167522 proC Streptococcus thermophilus CNRZ1066 pyrroline-5-carboxylate reductase YP_142181.1 1651048 D 299768 CDS YP_142182.1 55823741 3167520 complement(1651848..1652510) 1 NC_006449.1 hypothetical protein 1652510 3167520 str1853 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142182.1 1651848 R 299768 CDS YP_142183.1 55823742 3165751 complement(1652732..1653061) 1 NC_006449.1 hypothetical protein 1653061 3165751 str1854 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142183.1 1652732 R 299768 CDS YP_142184.1 55823743 3167521 complement(1653135..1653614) 1 NC_006449.1 truncated; hypothetical protein 1653614 3167521 str1855 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142184.1 1653135 R 299768 CDS YP_142185.1 55823744 3166460 complement(1653803..1654012) 1 NC_006449.1 transcriptional regulator 1654012 3166460 str1856 Streptococcus thermophilus CNRZ1066 transcriptional regulator YP_142185.1 1653803 R 299768 CDS YP_142186.1 55823745 3167510 complement(1654249..1655469) 1 NC_006449.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1655469 ackA 3167510 ackA Streptococcus thermophilus CNRZ1066 acetate kinase YP_142186.1 1654249 R 299768 CDS YP_142187.1 55823746 3167538 complement(1655498..1656454) 1 NC_006449.1 hypothetical protein 1656454 3167538 str1858 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142187.1 1655498 R 299768 CDS YP_142188.1 55823747 3165646 complement(1656499..1656816) 1 NC_006449.1 hypothetical protein 1656816 3165646 str1859 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142188.1 1656499 R 299768 CDS YP_142189.1 55823748 3167512 complement(1656794..1657255) 1 NC_006449.1 competence protein 1657255 3167512 str1860 Streptococcus thermophilus CNRZ1066 competence protein YP_142189.1 1656794 R 299768 CDS YP_142190.1 55823749 3167513 complement(1657215..1657508) 1 NC_006449.1 hypothetical protein 1657508 3167513 str1861 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142190.1 1657215 R 299768 CDS YP_142191.1 55823750 3167511 complement(1657480..1657908) 1 NC_006449.1 competence protein 1657908 comGD 3167511 comGD Streptococcus thermophilus CNRZ1066 competence protein YP_142191.1 1657480 R 299768 CDS YP_142192.1 55823751 3166723 complement(1657868..1658194) 1 NC_006449.1 late competence protein exogenous DNA-binding protein 1658194 comGC 3166723 comGC Streptococcus thermophilus CNRZ1066 late competence protein exogenous DNA-binding protein YP_142192.1 1657868 R 299768 CDS YP_142193.1 55823752 3167509 complement(1658191..1659297) 1 NC_006449.1 late competence protein ABC transporter subunit 1659297 comGB 3167509 comGB Streptococcus thermophilus CNRZ1066 late competence protein ABC transporter subunit YP_142193.1 1658191 R 299768 CDS YP_142194.1 55823753 3165910 complement(1659173..1660114) 1 NC_006449.1 late competence protein ABC transporter subunit 1660114 comGA 3165910 comGA Streptococcus thermophilus CNRZ1066 late competence protein ABC transporter subunit YP_142194.1 1659173 R 299768 CDS YP_142195.1 55823754 3167507 complement(1660195..1660557) 1 NC_006449.1 hypothetical protein 1660557 3167507 str1866 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142195.1 1660195 R 299768 CDS YP_142196.1 55823755 3167514 complement(1660716..1664354) 1 NC_006449.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1664354 rpoC 3167514 rpoC Streptococcus thermophilus CNRZ1066 DNA-directed RNA polymerase subunit beta' YP_142196.1 1660716 R 299768 CDS YP_142197.1 55823756 3166091 complement(1664455..1668036) 1 NC_006449.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1668036 rpoB 3166091 rpoB Streptococcus thermophilus CNRZ1066 DNA-directed RNA polymerase subunit beta YP_142197.1 1664455 R 299768 CDS YP_142198.1 55823757 3167504 complement(1668399..1670726) 1 NC_006449.1 penicillin-binding protein 1B 1670726 pbp1B 3167504 pbp1B Streptococcus thermophilus CNRZ1066 penicillin-binding protein 1B YP_142198.1 1668399 R 299768 CDS YP_142199.1 55823758 3166114 1670864..1672180 1 NC_006449.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1672180 tyrS 3166114 tyrS Streptococcus thermophilus CNRZ1066 tyrosyl-tRNA synthetase YP_142199.1 1670864 D 299768 CDS YP_142200.1 55823759 3167506 complement(1672306..1673328) 1 NC_006449.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1673328 ilvC 3167506 ilvC Streptococcus thermophilus CNRZ1066 ketol-acid reductoisomerase YP_142200.1 1672306 R 299768 CDS YP_142201.1 55823760 3166014 complement(1673404..1673880) 1 NC_006449.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1673880 ilvH 3166014 ilvH Streptococcus thermophilus CNRZ1066 acetolactate synthase 3 regulatory subunit YP_142201.1 1673404 R 299768 CDS YP_142202.1 55823761 3167502 complement(1673873..1675591) 1 NC_006449.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 1675591 ilvB 3167502 ilvB Streptococcus thermophilus CNRZ1066 acetolactate synthase catalytic subunit YP_142202.1 1673873 R 299768 CDS YP_142203.1 55823762 3166139 complement(1675681..1677198) 1 NC_006449.1 truncated; dihydroxy-acid dehydratase, truncated 1677198 3166139 str1874 Streptococcus thermophilus CNRZ1066 dihydroxy-acid dehydratase, truncated YP_142203.1 1675681 R 299768 CDS YP_142204.1 55823763 3167508 complement(1677598..1679265) 1 NC_006449.1 hypothetical protein 1679265 3167508 str1875 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142204.1 1677598 R 299768 CDS YP_142205.1 55823764 3166225 complement(1679265..1679630) 1 NC_006449.1 alkaline-shock protein 1679630 asp 3166225 asp Streptococcus thermophilus CNRZ1066 alkaline-shock protein YP_142205.1 1679265 R 299768 CDS YP_142206.1 55823765 3166223 complement(1679740..1681029) 1 NC_006449.1 MATE efflux family Na(+)/drug antiporter 1681029 norN 3166223 norN Streptococcus thermophilus CNRZ1066 MATE efflux family Na(+)/drug antiporter YP_142206.1 1679740 R 299768 CDS YP_142207.1 55823766 3166490 complement(1681087..1682571) 1 NC_006449.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1682571 thrC 3166490 thrC Streptococcus thermophilus CNRZ1066 threonine synthase YP_142207.1 1681087 R 299768 CDS YP_142208.1 55823767 3166030 complement(1683249..1683740) 1 NC_006449.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1683740 3166030 str1879 Streptococcus thermophilus CNRZ1066 alcohol-acetaldehyde dehydrogenase, truncated YP_142208.1 1683249 R 299768 CDS YP_142209.1 55823768 3167505 complement(1683776..1684222) 1 NC_006449.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1684222 3167505 str1881 Streptococcus thermophilus CNRZ1066 alcohol-acetaldehyde dehydrogenase, truncated YP_142209.1 1683776 R 299768 CDS YP_142210.1 55823769 3166362 complement(1684223..1684783) 1 NC_006449.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1684783 3166362 str1882 Streptococcus thermophilus CNRZ1066 alcohol-acetaldehyde dehydrogenase, truncated YP_142210.1 1684223 R 299768 CDS YP_142211.1 55823770 3166448 complement(1685127..1685204) 1 NC_006449.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1685204 3166448 str1883 Streptococcus thermophilus CNRZ1066 alcohol-acetaldehyde dehydrogenase, truncated YP_142211.1 1685127 R 299768 CDS YP_142212.1 55823771 3166390 complement(1685360..1685755) 1 NC_006449.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1685755 3166390 str1884 Streptococcus thermophilus CNRZ1066 alcohol-acetaldehyde dehydrogenase, truncated YP_142212.1 1685360 R 299768 CDS YP_142213.1 55823772 3166192 complement(1685894..1687789) 1 NC_006449.1 endopeptidase O 1687789 pepO 3166192 pepO Streptococcus thermophilus CNRZ1066 endopeptidase O YP_142213.1 1685894 R 299768 CDS YP_142214.1 55823773 3167503 complement(1687870..1688682) 1 NC_006449.1 truncated; trehalose-6-phosphate hydrolase, truncated 1688682 3167503 str1886 Streptococcus thermophilus CNRZ1066 trehalose-6-phosphate hydrolase, truncated YP_142214.1 1687870 R 299768 CDS YP_142215.1 55823774 3165645 complement(1688543..1688896) 1 NC_006449.1 truncated; trehalose-6-phosphate hydrolase, truncated 1688896 3165645 str1887 Streptococcus thermophilus CNRZ1066 trehalose-6-phosphate hydrolase, truncated YP_142215.1 1688543 R 299768 CDS YP_142216.1 55823775 3166613 complement(1688875..1688997) 1 NC_006449.1 truncated; trehalose-6-phosphate hydrolase, truncated 1688997 3166613 str1888 Streptococcus thermophilus CNRZ1066 trehalose-6-phosphate hydrolase, truncated YP_142216.1 1688875 R 299768 CDS YP_142217.1 55823776 3167501 complement(1689084..1689404) 1 NC_006449.1 truncated; PTS system trehalose-specific transporter subunit IIBC, truncated 1689404 3167501 str1889 Streptococcus thermophilus CNRZ1066 PTS system trehalose-specific transporter subunit IIBC, truncated YP_142217.1 1689084 R 299768 CDS YP_142218.1 55823777 3166234 complement(1689435..1689800) 1 NC_006449.1 truncated; PTS system trehalose-specific transporter subunit IIBC, truncated 1689800 3166234 str1890 Streptococcus thermophilus CNRZ1066 PTS system trehalose-specific transporter subunit IIBC, truncated YP_142218.1 1689435 R 299768 CDS YP_142219.1 55823778 3167500 complement(1689897..1690034) 1 NC_006449.1 truncated; PTS system trehalose-specific transporter subunit IIBC, truncated 1690034 3167500 str1891 Streptococcus thermophilus CNRZ1066 PTS system trehalose-specific transporter subunit IIBC, truncated YP_142219.1 1689897 R 299768 CDS YP_142220.1 55823779 3165790 1690146..1690304 1 NC_006449.1 truncated; trehalose operon transcriptional repressor 1690304 3165790 str1892 Streptococcus thermophilus CNRZ1066 trehalose operon transcriptional repressor YP_142220.1 1690146 D 299768 CDS YP_142221.1 55823780 3167496 1690359..1690856 1 NC_006449.1 truncated; trehalose operon transcriptional regulator truncated 1690856 3167496 str1893 Streptococcus thermophilus CNRZ1066 trehalose operon transcriptional regulator truncated YP_142221.1 1690359 D 299768 CDS YP_142222.1 55823781 3165925 complement(1690912..1691475) 1 NC_006449.1 hypothetical protein 1691475 3165925 str1894 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142222.1 1690912 R 299768 CDS YP_142223.1 55823782 3166176 complement(1691485..1691823) 1 NC_006449.1 hypothetical protein 1691823 3166176 str1895 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142223.1 1691485 R 299768 CDS YP_142224.1 55823783 3166365 complement(1691856..1692212) 1 NC_006449.1 hypothetical protein 1692212 3166365 str1896 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142224.1 1691856 R 299768 CDS YP_142225.1 55823784 3165737 1692880..1693248 1 NC_006449.1 truncated; hypothetical protein 1693248 3165737 str1897 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142225.1 1692880 D 299768 CDS YP_142226.1 55823785 3167499 1693348..1693467 1 NC_006449.1 truncated; hypothetical protein 1693467 3167499 str1898 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142226.1 1693348 D 299768 CDS YP_142227.1 55823786 3166238 complement(1693523..1694404) 1 NC_006449.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1694404 fba 3166238 fba Streptococcus thermophilus CNRZ1066 fructose-bisphosphate aldolase YP_142227.1 1693523 R 299768 CDS YP_142228.1 55823787 3166231 complement(1694822..1695427) 1 NC_006449.1 truncated; glutamate--cysteine ligase , truncated 1695427 3166231 str1900 Streptococcus thermophilus CNRZ1066 glutamate--cysteine ligase , truncated YP_142228.1 1694822 R 299768 CDS YP_142229.1 55823788 3166090 complement(1695485..1695673) 1 NC_006449.1 truncated; glutamate--cysteine ligase , truncated 1695673 3166090 str1901 Streptococcus thermophilus CNRZ1066 glutamate--cysteine ligase , truncated YP_142229.1 1695485 R 299768 CDS YP_142230.1 55823789 3167497 complement(1695734..1695880) 1 NC_006449.1 truncated; glutamate--cysteine ligase , truncated 1695880 3167497 str1902 Streptococcus thermophilus CNRZ1066 glutamate--cysteine ligase , truncated YP_142230.1 1695734 R 299768 CDS YP_142231.1 55823790 3167498 complement(1695977..1696117) 1 NC_006449.1 truncated; glutamate--cysteine ligase , truncated 1696117 3167498 str1903 Streptococcus thermophilus CNRZ1066 glutamate--cysteine ligase , truncated YP_142231.1 1695977 R 299768 CDS YP_142232.1 55823791 3166043 1696272..1696559 1 NC_006449.1 truncated; hypothetical protein 1696559 3166043 str1904 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142232.1 1696272 D 299768 CDS YP_142233.1 55823792 3167495 1696676..1697044 1 NC_006449.1 truncated; hypothetical protein 1697044 3167495 str1905 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142233.1 1696676 D 299768 CDS YP_142234.1 55823793 3165911 1697144..1697263 1 NC_006449.1 truncated; hypothetical protein 1697263 3165911 str1906 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142234.1 1697144 D 299768 CDS YP_142235.1 55823794 3166904 complement(1697459..1697845) 1 NC_006449.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1697845 rplQ 3166904 rplQ Streptococcus thermophilus CNRZ1066 50S ribosomal protein L17 YP_142235.1 1697459 R 299768 CDS YP_142236.1 55823795 3167331 complement(1697863..1698801) 1 NC_006449.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1698801 rpoA 3167331 rpoA Streptococcus thermophilus CNRZ1066 DNA-directed RNA polymerase subunit alpha YP_142236.1 1697863 R 299768 CDS YP_142237.1 55823796 3167347 complement(1698850..1699233) 1 NC_006449.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1699233 rpsK 3167347 rpsK Streptococcus thermophilus CNRZ1066 30S ribosomal protein S11 YP_142237.1 1698850 R 299768 CDS YP_142238.1 55823797 3166386 complement(1699261..1699626) 1 NC_006449.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1699626 rpsM 3166386 rpsM Streptococcus thermophilus CNRZ1066 30S ribosomal protein S13 YP_142238.1 1699261 R 299768 CDS YP_142239.1 55823798 3167407 complement(1699644..1699760) 1 NC_006449.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1699760 rpmJ 3167407 rpmJ Streptococcus thermophilus CNRZ1066 50S ribosomal protein L36 YP_142239.1 1699644 R 299768 CDS YP_142240.1 55823799 3165764 complement(1699786..1700004) 1 NC_006449.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1700004 infA 3165764 infA Streptococcus thermophilus CNRZ1066 translation initiation factor IF-1 YP_142240.1 1699786 R 299768 CDS YP_142241.1 55823800 3167304 complement(1700122..1700778) 1 NC_006449.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1700778 adk 3167304 adk Streptococcus thermophilus CNRZ1066 adenylate kinase YP_142241.1 1700122 R 299768 CDS YP_142242.1 55823801 3167345 complement(1700910..1702205) 1 NC_006449.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1702205 secY 3167345 secY Streptococcus thermophilus CNRZ1066 preprotein translocase subunit SecY YP_142242.1 1700910 R 299768 CDS YP_142243.2 161936359 3167325 complement(1702222..1702662) 1 NC_006449.1 late assembly protein; 50S ribosomal protein L15 1702662 rplO 3167325 rplO Streptococcus thermophilus CNRZ1066 50S ribosomal protein L15 YP_142243.2 1702222 R 299768 CDS YP_142244.1 55823803 3167305 complement(1702790..1702972) 1 NC_006449.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1702972 rpmD 3167305 rpmD Streptococcus thermophilus CNRZ1066 50S ribosomal protein L30 YP_142244.1 1702790 R 299768 CDS YP_142245.1 55823804 3167326 complement(1702987..1703481) 1 NC_006449.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1703481 rpsE 3167326 rpsE Streptococcus thermophilus CNRZ1066 30S ribosomal protein S5 YP_142245.1 1702987 R 299768 CDS YP_142246.2 161936358 3167355 complement(1703500..1703856) 1 NC_006449.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1703856 rplR 3167355 rplR Streptococcus thermophilus CNRZ1066 50S ribosomal protein L18 YP_142246.2 1703500 R 299768 CDS YP_142247.1 55823806 3165765 complement(1703946..1704482) 1 NC_006449.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1704482 rplF 3165765 rplF Streptococcus thermophilus CNRZ1066 50S ribosomal protein L6 YP_142247.1 1703946 R 299768 CDS YP_142248.1 55823807 3167322 complement(1704609..1705007) 1 NC_006449.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1705007 rpsH 3167322 rpsH Streptococcus thermophilus CNRZ1066 30S ribosomal protein S8 YP_142248.1 1704609 R 299768 CDS YP_142249.1 55823808 3166465 complement(1705130..1705315) 1 NC_006449.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1705315 rpsN 3166465 rpsN Streptococcus thermophilus CNRZ1066 30S ribosomal protein S14 YP_142249.1 1705130 R 299768 CDS YP_142250.1 55823809 3167311 complement(1705333..1705875) 1 NC_006449.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1705875 rplE 3167311 rplE Streptococcus thermophilus CNRZ1066 50S ribosomal protein L5 YP_142250.1 1705333 R 299768 CDS YP_142251.1 55823810 3166649 complement(1705902..1706207) 1 NC_006449.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1706207 rplX 3166649 rplX Streptococcus thermophilus CNRZ1066 50S ribosomal protein L24 YP_142251.1 1705902 R 299768 CDS YP_142252.1 55823811 3167315 complement(1706288..1706656) 1 NC_006449.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1706656 rplN 3167315 rplN Streptococcus thermophilus CNRZ1066 50S ribosomal protein L14 YP_142252.1 1706288 R 299768 CDS YP_142253.1 55823812 3166811 complement(1706681..1706941) 1 NC_006449.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1706941 rpsQ 3166811 rpsQ Streptococcus thermophilus CNRZ1066 30S ribosomal protein S17 YP_142253.1 1706681 R 299768 CDS YP_142254.1 55823813 3167298 complement(1706969..1707175) 1 NC_006449.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1707175 rpmC 3167298 rpmC Streptococcus thermophilus CNRZ1066 50S ribosomal protein L29 YP_142254.1 1706969 R 299768 CDS YP_142255.1 55823814 3167361 complement(1707185..1707598) 1 NC_006449.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1707598 rplP 3167361 rplP Streptococcus thermophilus CNRZ1066 50S ribosomal protein L16 YP_142255.1 1707185 R 299768 CDS YP_142256.1 55823815 3165767 complement(1707602..1708255) 1 NC_006449.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1708255 rpsC 3165767 rpsC Streptococcus thermophilus CNRZ1066 30S ribosomal protein S3 YP_142256.1 1707602 R 299768 CDS YP_142257.1 55823816 3167319 complement(1708268..1708612) 1 NC_006449.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1708612 rplV 3167319 rplV Streptococcus thermophilus CNRZ1066 50S ribosomal protein L22 YP_142257.1 1708268 R 299768 CDS YP_142258.1 55823817 3165768 complement(1708628..1708906) 1 NC_006449.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1708906 rpsS 3165768 rpsS Streptococcus thermophilus CNRZ1066 30S ribosomal protein S19 YP_142258.1 1708628 R 299768 CDS YP_142259.1 55823818 3167338 complement(1709000..1709833) 1 NC_006449.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1709833 rplB 3167338 rplB Streptococcus thermophilus CNRZ1066 50S ribosomal protein L2 YP_142259.1 1709000 R 299768 CDS YP_142260.1 55823819 3167339 complement(1709851..1710147) 1 NC_006449.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1710147 rplW 3167339 rplW Streptococcus thermophilus CNRZ1066 50S ribosomal protein L23 YP_142260.1 1709851 R 299768 CDS YP_142261.1 55823820 3167385 complement(1710147..1710770) 1 NC_006449.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1710770 rplD 3167385 rplD Streptococcus thermophilus CNRZ1066 50S ribosomal protein L4 YP_142261.1 1710147 R 299768 CDS YP_142262.1 55823821 3165769 complement(1710795..1711421) 1 NC_006449.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1711421 rplC 3165769 rplC Streptococcus thermophilus CNRZ1066 50S ribosomal protein L3 YP_142262.1 1710795 R 299768 CDS YP_142263.1 55823822 3167324 complement(1711538..1711846) 1 NC_006449.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1711846 rpsJ 3167324 rpsJ Streptococcus thermophilus CNRZ1066 30S ribosomal protein S10 YP_142263.1 1711538 R 299768 CDS YP_142264.1 55823823 3165771 complement(1712090..1713091) 1 NC_006449.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1713091 ruvB 3165771 ruvB Streptococcus thermophilus CNRZ1066 Holliday junction DNA helicase RuvB YP_142264.1 1712090 R 299768 CDS YP_142265.1 55823824 3167335 complement(1713174..1714997) 1 NC_006449.1 acyltransferase 1714997 3167335 str1937 Streptococcus thermophilus CNRZ1066 acyltransferase YP_142265.1 1713174 R 299768 CDS YP_142266.1 55823825 3165772 complement(1714994..1715404) 1 NC_006449.1 hypothetical protein 1715404 3165772 str1938 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142266.1 1714994 R 299768 CDS YP_142267.1 55823826 3167328 complement(1715401..1715835) 1 NC_006449.1 protein-tyrosine-phosphatase 1715835 3167328 str1939 Streptococcus thermophilus CNRZ1066 protein-tyrosine-phosphatase YP_142267.1 1715401 R 299768 CDS YP_142268.1 55823827 3167330 complement(1716117..1717409) 1 NC_006449.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1717409 purA 3167330 purA Streptococcus thermophilus CNRZ1066 adenylosuccinate synthetase YP_142268.1 1716117 R 299768 CDS YP_142269.1 55823828 3166562 complement(1717663..1718178) 1 NC_006449.1 topology modulation protein 1718178 flaR 3166562 flaR Streptococcus thermophilus CNRZ1066 topology modulation protein YP_142269.1 1717663 R 299768 CDS YP_142270.1 55823829 3167303 complement(1718468..1719637) 1 NC_006449.1 multidrug-efflux transporter 1719637 pmrB 3167303 pmrB Streptococcus thermophilus CNRZ1066 multidrug-efflux transporter YP_142270.1 1718468 R 299768 CDS YP_142271.1 55823830 3166705 complement(1719630..1720685) 1 NC_006449.1 bacteriocin biosynthesis protein 1720685 mccB 3166705 mccB Streptococcus thermophilus CNRZ1066 bacteriocin biosynthesis protein YP_142271.1 1719630 R 299768 CDS YP_142272.1 55823831 3165775 1721183..1721542 1 NC_006449.1 truncated; truncated IS1191 transposase 1721542 3165775 str1945 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_142272.1 1721183 D 299768 CDS YP_142273.1 55823832 3167329 1721575..1722381 1 NC_006449.1 truncated; truncated IS1191 transposase 1722381 3167329 str1946 Streptococcus thermophilus CNRZ1066 truncated IS1191 transposase YP_142273.1 1721575 D 299768 CDS YP_142274.1 55823833 3166138 1722744..1723637 1 NC_006449.1 MutR family transcriptional regulator 1723637 3166138 str1947 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator YP_142274.1 1722744 D 299768 CDS YP_142275.1 55823834 3166429 1723722..1725881 1 NC_006449.1 hypothetical protein 1725881 3166429 str1948 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142275.1 1723722 D 299768 CDS YP_142276.1 55823835 3167309 1726209..1727453 1 NC_006449.1 truncated; ABC transporter ATP binding/permease, truncated 1727453 3167309 str1949 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding/permease, truncated YP_142276.1 1726209 D 299768 CDS YP_142277.1 55823836 3167317 1728370..1729068 1 NC_006449.1 truncated; MutR family transcriptional regulator , truncated 1729068 3167317 str1950 Streptococcus thermophilus CNRZ1066 MutR family transcriptional regulator , truncated YP_142277.1 1728370 D 299768 CDS YP_142278.1 55823837 3165776 1729235..1730509 1 NC_006449.1 hypothetical protein 1730509 3165776 str1951 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142278.1 1729235 D 299768 CDS YP_142279.1 55823838 3165883 1730502..1732043 1 NC_006449.1 ABC transporter ATP binding/permease 1732043 3165883 str1952 Streptococcus thermophilus CNRZ1066 ABC transporter ATP binding/permease YP_142279.1 1730502 D 299768 CDS YP_142280.1 55823839 3165777 1732437..1733414 1 NC_006449.1 replication initiator protein 1733414 rip 3165777 rip Streptococcus thermophilus CNRZ1066 replication initiator protein YP_142280.1 1732437 D 299768 CDS YP_142281.1 55823840 3165631 1733426..1733614 1 NC_006449.1 hypothetical protein 1733614 3165631 str1954 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142281.1 1733426 D 299768 CDS YP_142282.1 55823841 3167308 1733616..1734755 1 NC_006449.1 integrase/recombinase 1734755 int4 3167308 int4 Streptococcus thermophilus CNRZ1066 integrase/recombinase YP_142282.1 1733616 D 299768 CDS YP_142283.1 55823842 3167313 complement(1734877..1735107) 1 NC_006449.1 hypothetical protein 1735107 3167313 str1956 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142283.1 1734877 R 299768 CDS YP_142284.1 55823843 3165773 complement(1735198..1736466) 1 NC_006449.1 recombination factor protein RarA 1736466 cshA 3165773 cshA Streptococcus thermophilus CNRZ1066 recombination factor protein RarA YP_142284.1 1735198 R 299768 CDS YP_142285.1 55823844 3167332 1736637..1736825 1 NC_006449.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1736825 rpmB 3167332 rpmB Streptococcus thermophilus CNRZ1066 50S ribosomal protein L28 YP_142285.1 1736637 D 299768 CDS YP_142286.1 55823845 3165784 1736952..1737218 1 NC_006449.1 hypothetical protein 1737218 3165784 str1959 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142286.1 1736952 D 299768 CDS YP_142287.1 55823846 3165783 1737218..1737637 1 NC_006449.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1737637 3165783 str1960 Streptococcus thermophilus CNRZ1066 Holliday junction resolvase-like protein YP_142287.1 1737218 D 299768 CDS YP_142288.1 55823847 3167320 1737716..1738051 1 NC_006449.1 hypothetical protein 1738051 3167320 str1961 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142288.1 1737716 D 299768 CDS YP_142289.1 55823848 3165786 1738264..1739910 1 NC_006449.1 hypothetical protein 1739910 3165786 str1962 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142289.1 1738264 D 299768 CDS YP_142290.1 55823849 3167346 1740020..1742224 1 NC_006449.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1742224 nrdD 3167346 nrdD Streptococcus thermophilus CNRZ1066 anaerobic ribonucleoside triphosphate reductase YP_142290.1 1740020 D 299768 CDS YP_142291.1 55823850 3166515 1742326..1742457 1 NC_006449.1 hypothetical protein 1742457 3166515 str1964 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142291.1 1742326 D 299768 CDS YP_142292.1 55823851 3167340 1742459..1742959 1 NC_006449.1 acetyltransferase 1742959 3167340 str1965 Streptococcus thermophilus CNRZ1066 acetyltransferase YP_142292.1 1742459 D 299768 CDS YP_142293.1 55823852 3167296 1742964..1743569 1 NC_006449.1 anaerobic ribonucleotide reductase activator 1743569 nrdG 3167296 nrdG Streptococcus thermophilus CNRZ1066 anaerobic ribonucleotide reductase activator YP_142293.1 1742964 D 299768 CDS YP_142294.1 55823853 3166424 complement(1743591..1744358) 1 NC_006449.1 hypothetical protein 1744358 3166424 str1967 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142294.1 1743591 R 299768 CDS YP_142295.1 55823854 3167343 complement(1744418..1745359) 1 NC_006449.1 hypothetical protein 1745359 3167343 str1968 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142295.1 1744418 R 299768 CDS YP_142296.1 55823855 3165729 complement(1745352..1747103) 1 NC_006449.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1747103 aspS 3165729 aspS Streptococcus thermophilus CNRZ1066 aspartyl-tRNA synthetase YP_142296.1 1745352 R 299768 CDS YP_142297.1 55823856 3167341 complement(1747213..1747635) 1 NC_006449.1 hypothetical protein 1747635 3167341 str1970 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142297.1 1747213 R 299768 CDS YP_142298.1 55823857 3167418 complement(1747643..1748923) 1 NC_006449.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1748923 hisS 3167418 hisS Streptococcus thermophilus CNRZ1066 histidyl-tRNA synthetase YP_142298.1 1747643 R 299768 CDS YP_142299.1 55823858 3166812 complement(1749234..1749992) 1 NC_006449.1 truncated; hypothetical protein 1749992 3166812 str1972 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142299.1 1749234 R 299768 CDS YP_142300.1 55823859 3165787 complement(1750140..1750367) 1 NC_006449.1 truncated; hypothetical protein 1750367 3165787 str1973 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142300.1 1750140 R 299768 CDS YP_142301.1 55823860 3167327 1750597..1750779 1 NC_006449.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1750779 rpmF 3167327 rpmF Streptococcus thermophilus CNRZ1066 50S ribosomal protein L32 YP_142301.1 1750597 D 299768 CDS YP_142302.1 55823861 3167337 1750795..1750944 1 NC_006449.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1750944 rpmG 3167337 rpmG Streptococcus thermophilus CNRZ1066 50S ribosomal protein L33 YP_142302.1 1750795 D 299768 CDS YP_142303.1 55823862 3167336 complement(1751165..1751398) 1 NC_006449.1 hypothetical protein 1751398 3167336 str1976 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142303.1 1751165 R 299768 CDS YP_142304.1 55823863 3165791 complement(1751398..1751652) 1 NC_006449.1 hypothetical protein 1751652 3165791 str1977 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142304.1 1751398 R 299768 CDS YP_142305.1 55823864 3166321 complement(1751711..1751890) 1 NC_006449.1 truncated; hypothetical protein 1751890 3166321 str1978 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142305.1 1751711 R 299768 CDS YP_142306.1 55823865 3167334 complement(1752278..1752592) 1 NC_006449.1 truncated; hypothetical protein 1752592 3167334 str1979 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142306.1 1752278 R 299768 CDS YP_142307.1 55823866 3167342 complement(1752938..1753528) 1 NC_006449.1 truncated; hypothetical protein 1753528 3167342 str1980 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142307.1 1752938 R 299768 CDS YP_142308.1 55823867 3165793 complement(1753584..1753955) 1 NC_006449.1 hypothetical protein 1753955 3165793 str1981 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142308.1 1753584 R 299768 CDS YP_142309.1 55823868 3167314 1754544..1754783 1 NC_006449.1 hypothetical protein 1754783 3167314 str1982 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142309.1 1754544 D 299768 CDS YP_142310.1 55823869 3166531 1754842..1755408 1 NC_006449.1 hypothetical protein 1755408 3166531 str1983 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142310.1 1754842 D 299768 CDS YP_142311.1 55823870 3165800 1755421..1755591 1 NC_006449.1 hypothetical protein 1755591 3165800 str1984 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142311.1 1755421 D 299768 CDS YP_142312.1 55823871 3167318 1755606..1756163 1 NC_006449.1 hypothetical protein 1756163 3167318 str1986 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142312.1 1755606 D 299768 CDS YP_142313.1 55823872 3166549 1756236..1756439 1 NC_006449.1 hypothetical protein 1756439 3166549 str1987 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142313.1 1756236 D 299768 CDS YP_142314.1 55823873 3167302 complement(1757031..1757582) 1 NC_006449.1 hypothetical protein 1757582 3167302 str1988 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142314.1 1757031 R 299768 CDS YP_142315.1 55823874 3167381 1757869..1758021 1 NC_006449.1 truncated; hypothetical protein 1758021 3167381 str1989 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142315.1 1757869 D 299768 CDS YP_142316.1 55823875 3167310 1758035..1758196 1 NC_006449.1 truncated; hypothetical protein 1758196 3167310 str1990 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142316.1 1758035 D 299768 CDS YP_142317.1 55823876 3166167 1758402..1758623 1 NC_006449.1 hypothetical protein 1758623 3166167 str1991 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142317.1 1758402 D 299768 CDS YP_142318.1 55823877 3167321 1758737..1759612 1 NC_006449.1 hypothetical protein 1759612 3167321 str1992 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142318.1 1758737 D 299768 CDS YP_142319.1 55823878 3167301 complement(1759649..1762018) 1 NC_006449.1 hypothetical protein 1762018 3167301 str1993 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142319.1 1759649 R 299768 CDS YP_142320.1 55823879 3167307 1762147..1762686 1 NC_006449.1 TetR/AcrR family transcriptional regulator 1762686 3167307 str1995 Streptococcus thermophilus CNRZ1066 TetR/AcrR family transcriptional regulator YP_142320.1 1762147 D 299768 CDS YP_142321.1 55823880 3166163 complement(1762764..1763126) 1 NC_006449.1 hypothetical protein 1763126 3166163 str1996 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142321.1 1762764 R 299768 CDS YP_142322.1 55823881 3165785 complement(1763657..1764310) 1 NC_006449.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1764310 rpsD 3165785 rpsD Streptococcus thermophilus CNRZ1066 30S ribosomal protein S4 YP_142322.1 1763657 R 299768 CDS YP_142323.1 55823882 3167316 complement(1764466..1764768) 1 NC_006449.1 hypothetical protein 1764768 3167316 str1998 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142323.1 1764466 R 299768 CDS YP_142324.1 55823883 3165811 complement(1764792..1766153) 1 NC_006449.1 unwinds double stranded DNA; replicative DNA helicase 1766153 holB 3165811 holB Streptococcus thermophilus CNRZ1066 replicative DNA helicase YP_142324.1 1764792 R 299768 CDS YP_142325.2 161936357 3165812 complement(1766197..1766655) 1 NC_006449.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1766655 rplI 3165812 rplI Streptococcus thermophilus CNRZ1066 50S ribosomal protein L9 YP_142325.2 1766197 R 299768 CDS YP_142326.1 55823885 3165813 complement(1766657..1768621) 1 NC_006449.1 hypothetical protein 1768621 3165813 str2001 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142326.1 1766657 R 299768 CDS YP_142327.1 55823886 3166280 complement(1768695..1770698) 1 NC_006449.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1770698 gidA 3166280 gidA Streptococcus thermophilus CNRZ1066 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_142327.1 1768695 R 299768 CDS YP_142328.1 55823887 3167434 complement(1770871..1771992) 1 NC_006449.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1771992 mnmA 3167434 mnmA Streptococcus thermophilus CNRZ1066 tRNA-specific 2-thiouridylase MnmA YP_142328.1 1770871 R 299768 CDS YP_142329.1 55823888 3167299 complement(1772131..1773861) 1 NC_006449.1 hypothetical protein 1773861 3167299 str2004 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142329.1 1772131 R 299768 CDS YP_142330.1 55823889 3165814 complement(1773948..1774577) 1 NC_006449.1 hypothetical protein 1774577 3165814 str2005 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142330.1 1773948 R 299768 CDS YP_142331.1 55823890 3165816 complement(1774818..1775372) 1 NC_006449.1 hypothetical protein 1775372 3165816 str2006 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142331.1 1774818 R 299768 CDS YP_142332.1 55823891 3166921 complement(1775676..1776470) 1 NC_006449.1 ABC transporter permease 1776470 3166921 str2007 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_142332.1 1775676 R 299768 CDS YP_142333.1 55823892 3166458 complement(1776463..1777305) 1 NC_006449.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 1777305 cbiO 3166458 cbiO Streptococcus thermophilus CNRZ1066 cobalt transporter ATP-binding subunit YP_142333.1 1776463 R 299768 CDS YP_142334.1 55823893 3165745 complement(1777281..1778111) 1 NC_006449.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 1778111 cbiO 3165745 cbiO Streptococcus thermophilus CNRZ1066 cobalt transporter ATP-binding subunit YP_142334.1 1777281 R 299768 CDS YP_142335.1 55823894 3167323 complement(1778124..1778666) 1 NC_006449.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1778666 pgsA 3167323 pgsA Streptococcus thermophilus CNRZ1066 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_142335.1 1778124 R 299768 CDS YP_142336.1 55823895 3167460 complement(1778679..1779536) 1 NC_006449.1 hypothetical protein 1779536 3167460 str2011 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142336.1 1778679 R 299768 CDS YP_142337.1 55823896 3165817 complement(1779595..1780872) 1 NC_006449.1 peptidase 1780872 3165817 str2012 Streptococcus thermophilus CNRZ1066 peptidase YP_142337.1 1779595 R 299768 CDS YP_142338.1 55823897 3165818 complement(1780874..1782124) 1 NC_006449.1 protease 1782124 3165818 str2013 Streptococcus thermophilus CNRZ1066 protease YP_142338.1 1780874 R 299768 CDS YP_142339.1 55823898 3165815 1782202..1782579 1 NC_006449.1 hypothetical protein 1782579 3165815 str2014 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142339.1 1782202 D 299768 CDS YP_142340.1 55823899 3166450 1782582..1783682 1 NC_006449.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1783682 recF 3166450 recF Streptococcus thermophilus CNRZ1066 recombination protein F YP_142340.1 1782582 D 299768 CDS YP_142341.1 55823900 3165820 complement(1783851..1785332) 1 NC_006449.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1785332 guaB 3165820 guaB Streptococcus thermophilus CNRZ1066 inosine 5'-monophosphate dehydrogenase YP_142341.1 1783851 R 299768 CDS YP_142342.1 55823901 3165819 complement(1785509..1786531) 1 NC_006449.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1786531 trpS 3165819 trpS Streptococcus thermophilus CNRZ1066 tryptophanyl-tRNA synthetase YP_142342.1 1785509 R 299768 CDS YP_142343.1 55823902 3165822 1786959..1787831 1 NC_006449.1 hypothetical protein 1787831 3165822 str2019 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142343.1 1786959 D 299768 CDS YP_142344.1 55823903 3165823 1787898..1789520 1 NC_006449.1 ABC transporter ATP-binding protein 1789520 3165823 str2020 Streptococcus thermophilus CNRZ1066 ABC transporter ATP-binding protein YP_142344.1 1787898 D 299768 CDS YP_142345.1 55823904 3166473 1789570..1792176 1 NC_006449.1 ABC transporter permease 1792176 3166473 str2021 Streptococcus thermophilus CNRZ1066 ABC transporter permease YP_142345.1 1789570 D 299768 CDS YP_142346.1 55823905 3167312 complement(1792721..1793404) 1 NC_006449.1 hypothetical protein 1793404 3167312 str2022 Streptococcus thermophilus CNRZ1066 hypothetical protein YP_142346.1 1792721 R 299768 CDS YP_142347.2 229557981 3167481 complement(1793420..1793899) 1 NC_006449.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1793899 3167481 str2023 Streptococcus thermophilus CNRZ1066 rRNA large subunit methyltransferase YP_142347.2 1793420 R 299768 CDS YP_142348.1 55823907 3167300 1794104..1795339 1 NC_006449.1 exported serine protease 1795339 htrA 3167300 htrA Streptococcus thermophilus CNRZ1066 exported serine protease YP_142348.1 1794104 D 299768 CDS YP_142349.1 55823908 3165824 1795405..1796172 1 NC_006449.1 chromosome segregation protein 1796172 spoJ 3165824 spoJ Streptococcus thermophilus CNRZ1066 chromosome segregation protein YP_142349.1 1795405 D 299768 CDS