-- dump date 20120504_163116 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_138546.1 55820104 3164689 186..1550 1 NC_006448.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1550 dnaA 3164689 dnaA Streptococcus thermophilus LMG 18311 chromosome replication initiator DnaA YP_138546.1 186 D 264199 CDS YP_138547.1 55820105 3164740 1705..2841 1 NC_006448.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2841 dnaN 3164740 dnaN Streptococcus thermophilus LMG 18311 DNA polymerase III subunit beta YP_138547.1 1705 D 264199 CDS YP_138548.1 55820106 3164987 2892..3083 1 NC_006448.1 hypothetical protein 3083 3164987 stu0003 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138548.1 2892 D 264199 CDS YP_138549.1 55820107 3164481 3296..4411 1 NC_006448.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4411 3164481 stu0004 Streptococcus thermophilus LMG 18311 GTP-dependent nucleic acid-binding protein EngD YP_138549.1 3296 D 264199 CDS YP_138550.1 55820108 3164040 4484..5053 1 NC_006448.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 5053 pth 3164040 pth Streptococcus thermophilus LMG 18311 peptidyl-tRNA hydrolase YP_138550.1 4484 D 264199 CDS YP_138551.1 55820109 3164963 5046..8552 1 NC_006448.1 transcription repair coupling factor 8552 trcF 3164963 trcF Streptococcus thermophilus LMG 18311 transcription repair coupling factor YP_138551.1 5046 D 264199 CDS YP_138552.1 55820110 3163979 8738..9013 1 NC_006448.1 hypothetical protein 9013 3163979 stu0007 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138552.1 8738 D 264199 CDS YP_138553.1 55820111 3164575 8997..9368 1 NC_006448.1 MesJ/Ycf62 family cell-cycle protein 9368 divIC 3164575 divIC Streptococcus thermophilus LMG 18311 MesJ/Ycf62 family cell-cycle protein YP_138553.1 8997 D 264199 CDS YP_138554.1 55820112 3164993 9496..10788 1 NC_006448.1 hypothetical protein 10788 3164993 stu0009 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138554.1 9496 D 264199 CDS YP_138555.1 55820113 3164886 10788..12053 1 NC_006448.1 cell-cycle protein MesJ/Ycf62 family 12053 3164886 stu0010 Streptococcus thermophilus LMG 18311 cell-cycle protein MesJ/Ycf62 family YP_138555.1 10788 D 264199 CDS YP_138556.1 55820114 3163932 12135..12677 1 NC_006448.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 12677 hpt 3163932 hpt Streptococcus thermophilus LMG 18311 hypoxanthine-guanine phosphoribosyltransferase YP_138556.1 12135 D 264199 CDS YP_138557.1 55820115 3163906 12693..14660 1 NC_006448.1 cell division protein 14660 ftsH 3163906 ftsH Streptococcus thermophilus LMG 18311 cell division protein YP_138557.1 12693 D 264199 CDS YP_138558.1 55820116 3163841 complement(14678..14899) 1 NC_006448.1 truncated; hypothetical protein 14899 3163841 stu0013 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138558.1 14678 R 264199 CDS YP_138559.1 55820117 3163827 complement(14978..15703) 1 NC_006448.1 truncated; hypothetical protein 15703 3163827 stu0014 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138559.1 14978 R 264199 CDS YP_138560.1 55820118 3165158 complement(15621..15905) 1 NC_006448.1 truncated; hypothetical protein 15905 3165158 stu0015 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138560.1 15621 R 264199 CDS YP_138561.1 55820119 3164499 15986..16246 1 NC_006448.1 truncated; hypothetical protein 16246 3164499 stu0016 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138561.1 15986 D 264199 CDS YP_138562.1 55820120 3165109 16446..16601 1 NC_006448.1 truncated; hypothetical protein 16601 3165109 stu0017 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138562.1 16446 D 264199 CDS YP_138563.1 55820121 3163901 16577..16915 1 NC_006448.1 truncated; hypothetical protein 16915 3163901 stu0018 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138563.1 16577 D 264199 CDS YP_138564.1 55820122 3164065 16929..17417 1 NC_006448.1 truncated; hypothetical protein 17417 3164065 stu0019 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138564.1 16929 D 264199 CDS YP_138565.1 55820123 3164850 24270..25100 1 NC_006448.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 25100 mreC 3164850 mreC Streptococcus thermophilus LMG 18311 rod shape-determining protein MreC YP_138565.1 24270 D 264199 CDS YP_138566.1 55820124 3164750 25048..25626 1 NC_006448.1 rod shape-determining protein MreD 25626 mreD 3164750 mreD Streptococcus thermophilus LMG 18311 rod shape-determining protein MreD YP_138566.1 25048 D 264199 CDS YP_138567.1 55820125 3163816 25711..27135 1 NC_006448.1 glucan binding protein 27135 pcsB 3163816 pcsB Streptococcus thermophilus LMG 18311 glucan binding protein YP_138567.1 25711 D 264199 CDS YP_138568.1 55820126 3163850 27337..28314 1 NC_006448.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 28314 prsA1 3163850 prsA1 Streptococcus thermophilus LMG 18311 ribose-phosphate pyrophosphokinase YP_138568.1 27337 D 264199 CDS YP_138569.1 55820127 3164437 complement(28393..28659) 1 NC_006448.1 truncated; truncated IS1193 transposase 28659 3164437 stu0024 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_138569.1 28393 R 264199 CDS YP_138570.1 55820128 3163762 complement(28782..29048) 1 NC_006448.1 truncated; truncated IS1193 transposase 29048 3163762 stu0025 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_138570.1 28782 R 264199 CDS YP_138571.1 55820129 3164061 29414..30598 1 NC_006448.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 30598 araT 3164061 araT Streptococcus thermophilus LMG 18311 aromatic amino acid aminotransferase YP_138571.1 29414 D 264199 CDS YP_138572.1 55820130 3165561 30585..31358 1 NC_006448.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 31358 recO 3165561 recO Streptococcus thermophilus LMG 18311 DNA repair protein RecO YP_138572.1 30585 D 264199 CDS YP_138573.1 55820131 3164394 31574..32578 1 NC_006448.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 32578 plsX 3164394 plsX Streptococcus thermophilus LMG 18311 glycerol-3-phosphate acyltransferase PlsX YP_138573.1 31574 D 264199 CDS YP_138574.1 55820132 3164316 32578..32823 1 NC_006448.1 acyl carrier protein 32823 acpP1 3164316 acpP1 Streptococcus thermophilus LMG 18311 acyl carrier protein YP_138574.1 32578 D 264199 CDS YP_138575.1 55820133 3164319 33109..33816 1 NC_006448.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 33816 purC 3164319 purC Streptococcus thermophilus LMG 18311 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_138575.1 33109 D 264199 CDS YP_138576.1 55820134 3164480 33848..37597 1 NC_006448.1 phosphoribosylformylglycinamidine synthase II 37597 purL 3164480 purL Streptococcus thermophilus LMG 18311 phosphoribosylformylglycinamidine synthase II YP_138576.1 33848 D 264199 CDS YP_138577.1 55820135 3164619 37766..39205 1 NC_006448.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 39205 purF 3164619 purF Streptococcus thermophilus LMG 18311 amidophosphoribosyltransferase YP_138577.1 37766 D 264199 CDS YP_138578.1 55820136 3163831 39236..40255 1 NC_006448.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 40255 purM 3163831 purM Streptococcus thermophilus LMG 18311 phosphoribosylaminoimidazole synthetase YP_138578.1 39236 D 264199 CDS YP_138579.1 55820137 3165077 40255..40809 1 NC_006448.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 40809 purN 3165077 purN Streptococcus thermophilus LMG 18311 phosphoribosylglycinamide formyltransferase YP_138579.1 40255 D 264199 CDS YP_138580.1 55820138 3163856 40827..42425 1 NC_006448.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 42425 purH 3163856 purH Streptococcus thermophilus LMG 18311 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_138580.1 40827 D 264199 CDS YP_138581.1 55820139 3163786 42596..43054 1 NC_006448.1 truncated; hypothetical protein 43054 3163786 stu0036 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138581.1 42596 D 264199 CDS YP_138582.1 55820140 3164637 43108..43422 1 NC_006448.1 truncated; hypothetical protein 43422 3164637 stu0037 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138582.1 43108 D 264199 CDS YP_138583.1 55820141 3164926 43472..43717 1 NC_006448.1 truncated; hypothetical protein 43717 3164926 stu0038 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138583.1 43472 D 264199 CDS YP_138584.1 55820142 3164132 complement(43821..44660) 1 NC_006448.1 cell wall protein, choline binding protein 44660 cbpD1 3164132 cbpD1 Streptococcus thermophilus LMG 18311 cell wall protein, choline binding protein YP_138584.1 43821 R 264199 CDS YP_138585.1 55820143 3164075 44968..46230 1 NC_006448.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 46230 purD 3164075 purD Streptococcus thermophilus LMG 18311 phosphoribosylamine--glycine ligase YP_138585.1 44968 D 264199 CDS YP_138586.1 55820144 3164268 46564..47064 1 NC_006448.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 47064 purE 3164268 purE Streptococcus thermophilus LMG 18311 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_138586.1 46564 D 264199 CDS YP_138587.1 55820145 3165193 47051..48142 1 NC_006448.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 48142 purK 3165193 purK Streptococcus thermophilus LMG 18311 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_138587.1 47051 D 264199 CDS YP_138588.1 55820146 3164194 48335..49090 1 NC_006448.1 hypothetical protein 49090 3164194 stu0043 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138588.1 48335 D 264199 CDS YP_138589.1 55820147 3164410 49162..49326 1 NC_006448.1 hypothetical protein 49326 3164410 stu0044 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138589.1 49162 D 264199 CDS YP_138590.1 55820148 3164110 49605..50903 1 NC_006448.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 50903 purB 3164110 purB Streptococcus thermophilus LMG 18311 adenylosuccinate lyase YP_138590.1 49605 D 264199 CDS YP_138591.1 55820149 3165618 complement(51414..52454) 1 NC_006448.1 IS1239 transposase 52454 tnp1239 3165618 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_138591.1 51414 R 264199 CDS YP_138592.1 55820150 3164079 complement(53012..54703) 1 NC_006448.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 54703 argS 3164079 argS Streptococcus thermophilus LMG 18311 arginyl-tRNA synthetase YP_138592.1 53012 R 264199 CDS YP_138593.1 55820151 3165547 54828..55286 1 NC_006448.1 arginine repressor ArgR 55286 argR 3165547 argR Streptococcus thermophilus LMG 18311 arginine repressor ArgR YP_138593.1 54828 D 264199 CDS YP_138594.1 55820152 3164969 55286..55645 1 NC_006448.1 hypothetical protein 55645 3164969 stu0049 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138594.1 55286 D 264199 CDS YP_138595.1 55820153 3164933 55638..58196 1 NC_006448.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 58196 mutS1 3164933 mutS1 Streptococcus thermophilus LMG 18311 DNA mismatch repair protein MutS YP_138595.1 55638 D 264199 CDS YP_138596.1 55820154 3164095 complement(58443..58685) 1 NC_006448.1 hypothetical protein 58685 3164095 stu0051 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138596.1 58443 R 264199 CDS YP_138597.1 55820155 3163960 complement(58699..59073) 1 NC_006448.1 hypothetical protein 59073 3163960 stu0052 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138597.1 58699 R 264199 CDS YP_138598.1 55820156 3165190 59297..59602 1 NC_006448.1 hypothetical protein 59602 3165190 stu0053 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138598.1 59297 D 264199 CDS YP_138599.1 55820157 3163886 59654..61597 1 NC_006448.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 61597 mutL 3163886 mutL Streptococcus thermophilus LMG 18311 DNA mismatch repair protein YP_138599.1 59654 D 264199 CDS YP_138600.1 55820158 3164033 61724..61948 1 NC_006448.1 hypothetical protein 61948 3164033 stu0055 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138600.1 61724 D 264199 CDS YP_138601.1 55820159 3164088 62100..62690 1 NC_006448.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 62690 ruvA 3164088 ruvA Streptococcus thermophilus LMG 18311 Holliday junction DNA helicase RuvA YP_138601.1 62100 D 264199 CDS YP_138602.1 55820160 3164836 62697..63251 1 NC_006448.1 3-methyl-adenine DNA glycosylase I 63251 tag 3164836 tag Streptococcus thermophilus LMG 18311 3-methyl-adenine DNA glycosylase I YP_138602.1 62697 D 264199 CDS YP_138603.1 55820161 3164587 63347..64618 1 NC_006448.1 competence damage-inducible protein A 64618 cinA 3164587 cinA Streptococcus thermophilus LMG 18311 competence damage-inducible protein A YP_138603.1 63347 D 264199 CDS YP_138604.1 55820162 3165147 64654..65808 1 NC_006448.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 65808 recA 3165147 recA Streptococcus thermophilus LMG 18311 recombinase A YP_138604.1 64654 D 264199 CDS YP_138605.1 55820163 3163895 65985..66383 1 NC_006448.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 66383 spxA 3163895 spxA Streptococcus thermophilus LMG 18311 transcriptional regulator Spx YP_138605.1 65985 D 264199 CDS YP_138606.1 55820164 3164718 72791..77185 1 NC_006448.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 77185 polC 3164718 polC Streptococcus thermophilus LMG 18311 DNA polymerase III PolC YP_138606.1 72791 D 264199 CDS YP_138607.1 55820165 3164370 77349..78590 1 NC_006448.1 aminopeptidase 78590 pepS 3164370 pepS Streptococcus thermophilus LMG 18311 aminopeptidase YP_138607.1 77349 D 264199 CDS YP_138608.1 55820166 3164917 78610..78840 1 NC_006448.1 hypothetical protein 78840 3164917 stu0064 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138608.1 78610 D 264199 CDS YP_138609.1 55820167 3164745 79043..79372 1 NC_006448.1 truncated; MarR family transcriptional regulator 79372 3164745 stu0065 Streptococcus thermophilus LMG 18311 MarR family transcriptional regulator YP_138609.1 79043 D 264199 CDS YP_138610.1 55820168 3163967 79490..80041 1 NC_006448.1 hypothetical protein 80041 3163967 stu0066 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138610.1 79490 D 264199 CDS YP_138611.1 55820169 3164320 complement(80091..80240) 1 NC_006448.1 truncated; hypothetical protein 80240 3164320 stu0067 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138611.1 80091 R 264199 CDS YP_138612.1 55820170 3164938 complement(80345..80578) 1 NC_006448.1 truncated; hypothetical protein 80578 3164938 stu0068 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138612.1 80345 R 264199 CDS YP_138613.1 55820171 3164103 complement(80592..80855) 1 NC_006448.1 truncated; hypothetical protein 80855 3164103 stu0069 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138613.1 80592 R 264199 CDS YP_138614.1 55820172 3164918 complement(80982..81254) 1 NC_006448.1 hypothetical protein 81254 3164918 stu0070 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138614.1 80982 R 264199 CDS YP_138615.1 55820173 3163912 complement(81472..81909) 1 NC_006448.1 truncated; bacteriocin self-immunity protein, truncated 81909 3163912 stu0071 Streptococcus thermophilus LMG 18311 bacteriocin self-immunity protein, truncated YP_138615.1 81472 R 264199 CDS YP_138616.1 55820174 3165031 complement(81906..82424) 1 NC_006448.1 truncated; bacteriocin self-immunity protein, truncated 82424 3165031 stu0072 Streptococcus thermophilus LMG 18311 bacteriocin self-immunity protein, truncated YP_138616.1 81906 R 264199 CDS YP_138617.1 55820175 3164167 82947..83714 1 NC_006448.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 83714 rpsB 3164167 rpsB Streptococcus thermophilus LMG 18311 30S ribosomal protein S2 YP_138617.1 82947 D 264199 CDS YP_138618.2 161611302 3165200 83825..84865 1 NC_006448.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 84865 tsf 3165200 tsf Streptococcus thermophilus LMG 18311 elongation factor Ts YP_138618.2 83825 D 264199 CDS YP_138619.1 55820177 3164169 complement(84976..85446) 1 NC_006448.1 hypothetical protein 85446 3164169 stu0075 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138619.1 84976 R 264199 CDS YP_138620.1 55820178 3165537 85690..86145 1 NC_006448.1 transcriptional regulator 86145 ctsR 3165537 ctsR Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138620.1 85690 D 264199 CDS YP_138621.1 55820179 3164874 86146..88596 1 NC_006448.1 ATP-dependent Clp protease, ATP-binding subunit 88596 clpC 3164874 clpC Streptococcus thermophilus LMG 18311 ATP-dependent Clp protease, ATP-binding subunit YP_138621.1 86146 D 264199 CDS YP_138622.1 55820180 3164615 complement(88724..89545) 1 NC_006448.1 truncated; D-alanyl-D-alanine carboxypeptidase, truncated 89545 3164615 stu0078 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine carboxypeptidase, truncated YP_138622.1 88724 R 264199 CDS YP_138623.1 55820181 3163907 complement(89607..89774) 1 NC_006448.1 truncated; D-alanyl-D-alanine carboxypeptidase, truncated 89774 3163907 stu0079 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine carboxypeptidase, truncated YP_138623.1 89607 R 264199 CDS YP_138624.1 55820182 3163971 complement(90127..91395) 1 NC_006448.1 D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 91395 dacA1 3163971 dacA1 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein YP_138624.1 90127 R 264199 CDS YP_138625.1 55820183 3163849 91583..93808 1 NC_006448.1 polynucleotide phosphorylase 93808 pnpA 3163849 pnpA Streptococcus thermophilus LMG 18311 polynucleotide phosphorylase YP_138625.1 91583 D 264199 CDS YP_138626.1 55820184 3164078 93817..94587 1 NC_006448.1 hypothetical protein 94587 3164078 stu0082 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138626.1 93817 D 264199 CDS YP_138627.1 55820185 3164589 94651..95280 1 NC_006448.1 serine acetyltransferase 95280 cysE1 3164589 cysE1 Streptococcus thermophilus LMG 18311 serine acetyltransferase YP_138627.1 94651 D 264199 CDS YP_138628.1 55820186 3163839 95662..97005 1 NC_006448.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 97005 cysS 3163839 cysS Streptococcus thermophilus LMG 18311 cysteinyl-tRNA synthetase YP_138628.1 95662 D 264199 CDS YP_138629.1 55820187 3163880 96998..97399 1 NC_006448.1 hypothetical protein 97399 3163880 stu0085 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138629.1 96998 D 264199 CDS YP_138630.1 55820188 3163956 97682..97837 1 NC_006448.1 hypothetical protein 97837 3163956 stu0086 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138630.1 97682 D 264199 CDS YP_138631.1 55820189 3164824 97913..98101 1 NC_006448.1 hypothetical protein 98101 3164824 stu0087 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138631.1 97913 D 264199 CDS YP_138632.1 55820190 3164100 98463..99206 1 NC_006448.1 tRNA/rRNA methyltransferase 99206 trmH 3164100 trmH Streptococcus thermophilus LMG 18311 tRNA/rRNA methyltransferase YP_138632.1 98463 D 264199 CDS YP_138633.1 55820191 3165161 99209..99724 1 NC_006448.1 hypothetical protein 99724 3165161 stu0089 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138633.1 99209 D 264199 CDS YP_138634.1 55820192 3164096 99733..100593 1 NC_006448.1 hypothetical protein 100593 3164096 stu0090 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138634.1 99733 D 264199 CDS YP_138635.1 55820193 3164060 100894..101364 1 NC_006448.1 hypothetical protein 101364 3164060 stu0091 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138635.1 100894 D 264199 CDS YP_138636.1 55820194 3165152 101543..102499 1 NC_006448.1 2-dehydropantoate 2-reductase 102499 panE 3165152 panE Streptococcus thermophilus LMG 18311 2-dehydropantoate 2-reductase YP_138636.1 101543 D 264199 CDS YP_138637.1 55820195 3163814 102708..103154 1 NC_006448.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 103154 rplM 3163814 rplM Streptococcus thermophilus LMG 18311 50S ribosomal protein L13 YP_138637.1 102708 D 264199 CDS YP_138638.1 55820196 3164409 103182..103574 1 NC_006448.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 103574 rpsI 3164409 rpsI Streptococcus thermophilus LMG 18311 30S ribosomal protein S9 YP_138638.1 103182 D 264199 CDS YP_138639.1 55820197 3164235 complement(103734..103976) 1 NC_006448.1 truncated; integrase/recombinase, truncated 103976 3164235 stu0095 Streptococcus thermophilus LMG 18311 integrase/recombinase, truncated YP_138639.1 103734 R 264199 CDS YP_138640.1 55820198 3163940 104051..104314 1 NC_006448.1 truncated; transcriptional regulator, truncated 104314 3163940 stu0096 Streptococcus thermophilus LMG 18311 transcriptional regulator, truncated YP_138640.1 104051 D 264199 CDS YP_138641.1 55820199 3163835 104564..104668 1 NC_006448.1 hypothetical protein 104668 3163835 stu0097 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138641.1 104564 D 264199 CDS YP_138642.1 55820200 3164002 104847..107651 1 NC_006448.1 lantibiotic biosynthesis protein 107651 labB 3164002 labB Streptococcus thermophilus LMG 18311 lantibiotic biosynthesis protein YP_138642.1 104847 D 264199 CDS YP_138643.1 55820201 3164001 107689..108912 1 NC_006448.1 lantibiotic biosynthesis protein 108912 labC 3164001 labC Streptococcus thermophilus LMG 18311 lantibiotic biosynthesis protein YP_138643.1 107689 D 264199 CDS YP_138644.1 55820202 3164928 108936..109811 1 NC_006448.1 bacteriocin exporter 109811 labT 3164928 labT Streptococcus thermophilus LMG 18311 bacteriocin exporter YP_138644.1 108936 D 264199 CDS YP_138645.1 55820203 3164044 110429..110941 1 NC_006448.1 hypothetical protein 110941 3164044 stu0101 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138645.1 110429 D 264199 CDS YP_138646.1 55820204 3163999 complement(111278..112495) 1 NC_006448.1 phage integrase family integrase/recombinase 112495 int 3163999 int Streptococcus thermophilus LMG 18311 phage integrase family integrase/recombinase YP_138646.1 111278 R 264199 CDS YP_138647.1 55820205 3164793 complement(112976..114031) 1 NC_006448.1 hypothetical protein 114031 3164793 stu0103 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138647.1 112976 R 264199 CDS YP_138648.1 55820206 3165619 complement(114278..114535) 1 NC_006448.1 truncated; hypothetical protein 114535 3165619 stu0106 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138648.1 114278 R 264199 CDS YP_138649.1 55820207 3164584 complement(115043..115426) 1 NC_006448.1 truncated; truncated IS1216 transposase 115426 3164584 stu0107 Streptococcus thermophilus LMG 18311 truncated IS1216 transposase YP_138649.1 115043 R 264199 CDS YP_138650.1 55820208 3163766 complement(115451..115729) 1 NC_006448.1 truncated; truncated IS1216 transposase 115729 3163766 stu0108 Streptococcus thermophilus LMG 18311 truncated IS1216 transposase YP_138650.1 115451 R 264199 CDS YP_138651.1 55820209 3163753 115915..117096 1 NC_006448.1 hypothetical protein 117096 3163753 stu0110 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138651.1 115915 D 264199 CDS YP_138652.1 55820210 3164507 117418..117684 1 NC_006448.1 ACT domain-containing protein; hypothetical protein 117684 3164507 stu0112 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138652.1 117418 D 264199 CDS YP_138653.1 55820211 3164764 117696..119039 1 NC_006448.1 hypothetical protein 119039 3164764 stu0113 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138653.1 117696 D 264199 CDS YP_138654.1 55820212 3164113 119156..119578 1 NC_006448.1 truncated; phosphoglycerate mutase, truncated 119578 3164113 stu0114 Streptococcus thermophilus LMG 18311 phosphoglycerate mutase, truncated YP_138654.1 119156 D 264199 CDS YP_138655.1 55820213 3163981 119701..119880 1 NC_006448.1 truncated; phosphoglycerate mutase, truncated 119880 3163981 stu0115 Streptococcus thermophilus LMG 18311 phosphoglycerate mutase, truncated YP_138655.1 119701 D 264199 CDS YP_138656.1 55820214 3164456 119867..120664 1 NC_006448.1 D-alanyl-D-alanine-carboxypeptidase 120664 dacB 3164456 dacB Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine-carboxypeptidase YP_138656.1 119867 D 264199 CDS YP_138657.1 55820215 3164652 120661..121245 1 NC_006448.1 peptidoglycan hydrolase 121245 mur3 3164652 mur3 Streptococcus thermophilus LMG 18311 peptidoglycan hydrolase YP_138657.1 120661 D 264199 CDS YP_138658.1 55820216 3164703 121435..122517 1 NC_006448.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 122517 hrcA 3164703 hrcA Streptococcus thermophilus LMG 18311 heat-inducible transcription repressor YP_138658.1 121435 D 264199 CDS YP_138659.1 55820217 3164252 122501..123082 1 NC_006448.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 123082 grpE 3164252 grpE Streptococcus thermophilus LMG 18311 heat shock protein GrpE YP_138659.1 122501 D 264199 CDS YP_138660.1 55820218 3164693 123211..125034 1 NC_006448.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 125034 dnaK 3164693 dnaK Streptococcus thermophilus LMG 18311 molecular chaperone DnaK YP_138660.1 123211 D 264199 CDS YP_138661.1 55820219 3165008 125461..126594 1 NC_006448.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 126594 dnaJ 3165008 dnaJ Streptococcus thermophilus LMG 18311 molecular chaperone DnaJ YP_138661.1 125461 D 264199 CDS YP_138662.1 55820220 3165101 126700..127446 1 NC_006448.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 127446 truA 3165101 truA Streptococcus thermophilus LMG 18311 tRNA pseudouridine synthase A YP_138662.1 126700 D 264199 CDS YP_138663.1 55820221 3164024 127439..128200 1 NC_006448.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 128200 thiD 3164024 thiD Streptococcus thermophilus LMG 18311 phosphomethylpyrimidine kinase YP_138663.1 127439 D 264199 CDS YP_138664.1 55820222 3164012 128291..128659 1 NC_006448.1 hypothetical protein 128659 3164012 stu0124 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138664.1 128291 D 264199 CDS YP_138665.1 55820223 3164291 140604..142571 1 NC_006448.1 oligopeptide ABC uptake transporter substrate-binding protein 142571 amiA2 3164291 amiA2 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate-binding protein YP_138665.1 140604 D 264199 CDS YP_138666.1 55820224 3164023 complement(142609..143520) 1 NC_006448.1 truncated; truncated IS1193 transposase 143520 3164023 stu0126 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_138666.1 142609 R 264199 CDS YP_138667.1 55820225 3164389 144438..144866 1 NC_006448.1 truncated; aminoacylase/N-acyl-L-amino acid amidohydrolase, truncated 144866 3164389 stu0127 Streptococcus thermophilus LMG 18311 aminoacylase/N-acyl-L-amino acid amidohydrolase, truncated YP_138667.1 144438 D 264199 CDS YP_138668.1 55820226 3163935 144960..146159 1 NC_006448.1 cyclopropane-fatty-acyl-phospholipid synthase 146159 cfa 3163935 cfa Streptococcus thermophilus LMG 18311 cyclopropane-fatty-acyl-phospholipid synthase YP_138668.1 144960 D 264199 CDS YP_138669.1 55820227 3164588 complement(146390..146884) 1 NC_006448.1 truncated; truncated IS1193 transposase 146884 3164588 stu0129 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_138669.1 146390 R 264199 CDS YP_138670.1 55820228 3163739 147638..148135 1 NC_006448.1 transcriptional regulator 148135 comX 3163739 comX Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138670.1 147638 D 264199 CDS YP_138671.1 55820229 3164420 complement(148235..149077) 1 NC_006448.1 mechanosensitive ion channel MscS 149077 3164420 stu0131 Streptococcus thermophilus LMG 18311 mechanosensitive ion channel MscS YP_138671.1 148235 R 264199 CDS YP_138672.1 55820230 3165119 149218..150501 1 NC_006448.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 150501 tig 3165119 tig Streptococcus thermophilus LMG 18311 trigger factor YP_138672.1 149218 D 264199 CDS YP_138673.1 55820231 3164435 150659..151240 1 NC_006448.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 151240 rpoE 3164435 rpoE Streptococcus thermophilus LMG 18311 DNA-directed RNA polymerase subunit delta YP_138673.1 150659 D 264199 CDS YP_138674.1 55820232 3164539 151491..153095 1 NC_006448.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 153095 pyrG 3164539 pyrG Streptococcus thermophilus LMG 18311 CTP synthetase YP_138674.1 151491 D 264199 CDS YP_138675.1 55820233 3164032 153190..153660 1 NC_006448.1 hypothetical protein 153660 3164032 stu0135 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138675.1 153190 D 264199 CDS YP_138676.1 55820234 3163989 153676..154122 1 NC_006448.1 MutT/nudix family protein 154122 3163989 stu0136 Streptococcus thermophilus LMG 18311 MutT/nudix family protein YP_138676.1 153676 D 264199 CDS YP_138677.1 55820235 3164711 154122..155075 1 NC_006448.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 155075 prmA 3164711 prmA Streptococcus thermophilus LMG 18311 ribosomal protein L11 methyltransferase YP_138677.1 154122 D 264199 CDS YP_138678.1 55820236 3164699 155076..155819 1 NC_006448.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 155819 3164699 stu0138 Streptococcus thermophilus LMG 18311 16S ribosomal RNA methyltransferase RsmE YP_138678.1 155076 D 264199 CDS YP_138679.1 55820237 3164942 156114..156494 1 NC_006448.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 156494 3164942 stu0139 Streptococcus thermophilus LMG 18311 cyclo-nucleotide phosphodiesterase, truncated YP_138679.1 156114 D 264199 CDS YP_138680.1 55820238 3164222 156514..156699 1 NC_006448.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 156699 3164222 stu0140 Streptococcus thermophilus LMG 18311 cyclo-nucleotide phosphodiesterase, truncated YP_138680.1 156514 D 264199 CDS YP_138681.1 55820239 3164035 156683..157444 1 NC_006448.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 157444 3164035 stu0141 Streptococcus thermophilus LMG 18311 cyclo-nucleotide phosphodiesterase, truncated YP_138681.1 156683 D 264199 CDS YP_138682.1 55820240 3164066 157456..158205 1 NC_006448.1 truncated; cyclo-nucleotide phosphodiesterase, truncated 158205 3164066 stu0142 Streptococcus thermophilus LMG 18311 cyclo-nucleotide phosphodiesterase, truncated YP_138682.1 157456 D 264199 CDS YP_138683.1 55820241 3164226 158195..158584 1 NC_006448.1 hypothetical protein 158584 3164226 stu0143 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138683.1 158195 D 264199 CDS YP_138684.1 55820242 3164045 complement(158571..159098) 1 NC_006448.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 159098 nrdI 3164045 nrdI Streptococcus thermophilus LMG 18311 flavoprotein NrdI YP_138684.1 158571 R 264199 CDS YP_138685.1 55820243 3164475 159198..161417 1 NC_006448.1 (p)ppGpp synthetase 161417 relA 3164475 relA Streptococcus thermophilus LMG 18311 (p)ppGpp synthetase YP_138685.1 159198 D 264199 CDS YP_138686.1 55820244 3164029 161430..161873 1 NC_006448.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 161873 dtd 3164029 dtd Streptococcus thermophilus LMG 18311 D-tyrosyl-tRNA(Tyr) deacylase YP_138686.1 161430 D 264199 CDS YP_138687.1 55820245 3164038 162314..162598 1 NC_006448.1 truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 162598 3164038 stu0147 Streptococcus thermophilus LMG 18311 1,6-alpha-glucanhydrolase (dextranase), truncated YP_138687.1 162314 D 264199 CDS YP_138688.1 55820246 3165015 162753..163043 1 NC_006448.1 truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 163043 3165015 stu0148 Streptococcus thermophilus LMG 18311 1,6-alpha-glucanhydrolase (dextranase), truncated YP_138688.1 162753 D 264199 CDS YP_138689.1 55820247 3164792 163239..163850 1 NC_006448.1 truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 163850 3164792 stu0149 Streptococcus thermophilus LMG 18311 1,6-alpha-glucanhydrolase (dextranase), truncated YP_138689.1 163239 D 264199 CDS YP_138690.1 55820248 3165033 164150..165400 1 NC_006448.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 165400 ilvA 3165033 ilvA Streptococcus thermophilus LMG 18311 threonine dehydratase YP_138690.1 164150 D 264199 CDS YP_138691.1 55820249 3163998 complement(165561..166175) 1 NC_006448.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 166175 def 3163998 def Streptococcus thermophilus LMG 18311 peptide deformylase YP_138691.1 165561 R 264199 CDS YP_138692.1 55820250 3164041 complement(166277..166915) 1 NC_006448.1 transcriptional regulator 166915 3164041 stu0152 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138692.1 166277 R 264199 CDS YP_138693.1 55820251 3163893 167022..168185 1 NC_006448.1 hypothetical protein 168185 3163893 stu0153 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138693.1 167022 D 264199 CDS YP_138694.1 55820252 3164150 168334..168603 1 NC_006448.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 168603 rpsO 3164150 rpsO Streptococcus thermophilus LMG 18311 30S ribosomal protein S15 YP_138694.1 168334 D 264199 CDS YP_138695.1 55820253 3164733 complement(168833..169414) 1 NC_006448.1 hypothetical protein 169414 3164733 stu0155 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138695.1 168833 R 264199 CDS YP_138696.1 55820254 3164783 169983..170153 1 NC_006448.1 hypothetical protein 170153 3164783 stu0156 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138696.1 169983 D 264199 CDS YP_138697.1 55820255 3163819 170240..170347 1 NC_006448.1 hypothetical protein 170347 3163819 stu0157 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138697.1 170240 D 264199 CDS YP_138698.1 55820256 3164768 complement(170436..171176) 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 171176 3164768 stu0158 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_138698.1 170436 R 264199 CDS YP_138699.1 55820257 3164674 complement(171176..172726) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein/membrane-spanning protein 172726 3164674 stu0159 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein/membrane-spanning protein YP_138699.1 171176 R 264199 CDS YP_138700.1 55820258 3165178 172917..173783 1 NC_006448.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 173783 uppP 3165178 uppP Streptococcus thermophilus LMG 18311 undecaprenyl pyrophosphate phosphatase YP_138700.1 172917 D 264199 CDS YP_138701.1 55820259 3164053 complement(173929..174144) 1 NC_006448.1 hypothetical protein 174144 3164053 stu0161 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138701.1 173929 R 264199 CDS YP_138702.1 55820260 3164052 174410..175159 1 NC_006448.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 175159 mecA 3164052 mecA Streptococcus thermophilus LMG 18311 adaptor protein YP_138702.1 174410 D 264199 CDS YP_138703.1 55820261 3164984 175163..176320 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 176320 rgpG 3164984 rgpG Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_138703.1 175163 D 264199 CDS YP_138704.1 55820262 3164616 176448..177251 1 NC_006448.1 ABC transporter ATP binding protein 177251 3164616 stu0164 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_138704.1 176448 D 264199 CDS YP_138705.1 55820263 3164657 177288..178550 1 NC_006448.1 hypothetical protein 178550 3164657 stu0165 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138705.1 177288 D 264199 CDS YP_138706.1 55820264 3164275 178604..179836 1 NC_006448.1 aminotransferase 179836 nifS1 3164275 nifS1 Streptococcus thermophilus LMG 18311 aminotransferase YP_138706.1 178604 D 264199 CDS YP_138707.1 55820265 3164744 179802..180257 1 NC_006448.1 NifU family protein 180257 nifU 3164744 nifU Streptococcus thermophilus LMG 18311 NifU family protein YP_138707.1 179802 D 264199 CDS YP_138708.1 55820266 3165064 180337..181755 1 NC_006448.1 hypothetical protein 181755 3165064 stu0168 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138708.1 180337 D 264199 CDS YP_138709.1 55820267 3163784 182039..182245 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter substrate binding protein, truncated 182245 3163784 stu0169 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate binding protein, truncated YP_138709.1 182039 D 264199 CDS YP_138710.1 55820268 3163799 182220..183074 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter substrate binding protein, truncated 183074 3163799 stu0170 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate binding protein, truncated YP_138710.1 182220 D 264199 CDS YP_138711.1 55820269 3165586 183064..183273 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 183273 3165586 stu0171 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-spanning protein, truncated YP_138711.1 183064 D 264199 CDS YP_138712.1 55820270 3163858 183403..183951 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 183951 3163858 stu0172 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-spanning protein, truncated YP_138712.1 183403 D 264199 CDS YP_138713.1 55820271 3164071 183932..184318 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 184318 3164071 stu0173 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-spanning protein, truncated YP_138713.1 183932 D 264199 CDS YP_138714.1 55820272 3164914 184290..184532 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 184532 3164914 stu0174 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP binding protein, truncated YP_138714.1 184290 D 264199 CDS YP_138715.1 55820273 3164401 184562..184765 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 184765 3164401 stu0175 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP binding protein, truncated YP_138715.1 184562 D 264199 CDS YP_138716.1 55820274 3164364 184743..185141 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 185141 3164364 stu0176 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP binding protein, truncated YP_138716.1 184743 D 264199 CDS YP_138717.1 55820275 3164236 185036..185374 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 185374 3164236 stu0177 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP binding protein, truncated YP_138717.1 185036 D 264199 CDS YP_138718.1 55820276 3164902 185376..186314 1 NC_006448.1 oligopeptide ABC uptake transporter membrane-spanning protein 186314 optF 3164902 optF Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-spanning protein YP_138718.1 185376 D 264199 CDS YP_138719.1 55820277 3164400 186536..186724 1 NC_006448.1 hypothetical protein 186724 3164400 stu0179 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138719.1 186536 D 264199 CDS YP_138720.1 55820278 3164547 186850..187737 1 NC_006448.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 187737 hslO 3164547 hslO Streptococcus thermophilus LMG 18311 heat shock protein 33 YP_138720.1 186850 D 264199 CDS YP_138721.1 55820279 3164111 187655..188707 1 NC_006448.1 transcriptional regulator 188707 nifR 3164111 nifR Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138721.1 187655 D 264199 CDS YP_138722.1 55820280 3164656 189057..189773 1 NC_006448.1 MutR family transcriptional regulator 189773 3164656 stu0182 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_138722.1 189057 D 264199 CDS YP_138723.1 55820281 3164586 190043..192382 1 NC_006448.1 protein kinase 192382 3164586 stu0183 Streptococcus thermophilus LMG 18311 protein kinase YP_138723.1 190043 D 264199 CDS YP_138724.1 55820282 3164732 192383..193651 1 NC_006448.1 hypothetical protein 193651 3164732 stu0184 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138724.1 192383 D 264199 CDS YP_138725.1 55820283 3164452 193745..194200 1 NC_006448.1 zinc transport transcriptional repressor 194200 adcR 3164452 adcR Streptococcus thermophilus LMG 18311 zinc transport transcriptional repressor YP_138725.1 193745 D 264199 CDS YP_138726.1 55820284 3163926 194202..194909 1 NC_006448.1 zinc (Zn2+) ABC uptake transporter ATP-binding protein 194909 adcC 3163926 adcC Streptococcus thermophilus LMG 18311 zinc (Zn2+) ABC uptake transporter ATP-binding protein YP_138726.1 194202 D 264199 CDS YP_138727.1 55820285 3164186 194875..195714 1 NC_006448.1 zinc (Zn2+) ABC uptake transporter membrane-spanning protein 195714 adcB 3164186 adcB Streptococcus thermophilus LMG 18311 zinc (Zn2+) ABC uptake transporter membrane-spanning protein YP_138727.1 194875 D 264199 CDS YP_138728.1 55820286 3164412 195876..196814 1 NC_006448.1 AEC family permease 196814 mleP 3164412 mleP Streptococcus thermophilus LMG 18311 AEC family permease YP_138728.1 195876 D 264199 CDS YP_138729.1 55820287 3164639 196929..197360 1 NC_006448.1 truncated; glucose PTS enzyme component IIABC, truncated 197360 3164639 stu0189 Streptococcus thermophilus LMG 18311 glucose PTS enzyme component IIABC, truncated YP_138729.1 196929 D 264199 CDS YP_138730.1 55820288 3165042 197474..197590 1 NC_006448.1 truncated; glucose PTS enzyme component IIABC, truncated 197590 3165042 stu0190 Streptococcus thermophilus LMG 18311 glucose PTS enzyme component IIABC, truncated YP_138730.1 197474 D 264199 CDS YP_138731.1 55820289 3164176 197606..198532 1 NC_006448.1 truncated; glucose PTS enzyme component IIABC, truncated 198532 3164176 stu0191 Streptococcus thermophilus LMG 18311 glucose PTS enzyme component IIABC, truncated YP_138731.1 197606 D 264199 CDS YP_138732.1 55820290 3165185 198483..199151 1 NC_006448.1 truncated; glucose PTS enzyme component IIABC, truncated 199151 3165185 stu0192 Streptococcus thermophilus LMG 18311 glucose PTS enzyme component IIABC, truncated YP_138732.1 198483 D 264199 CDS YP_138733.1 55820291 3164220 199192..200064 1 NC_006448.1 hypothetical protein 200064 3164220 stu0193 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138733.1 199192 D 264199 CDS YP_138734.1 55820292 3164355 200149..201522 1 NC_006448.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 201522 pgi 3164355 pgi Streptococcus thermophilus LMG 18311 glucose-6-phosphate isomerase YP_138734.1 200149 D 264199 CDS YP_138735.2 161611301 3164978 201710..202426 1 NC_006448.1 hypothetical protein 202426 3164978 stu0195 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138735.2 201710 D 264199 CDS YP_138736.1 55820294 3164912 202552..202890 1 NC_006448.1 preprotein translocase subunit YajC 202890 yajC 3164912 yajC Streptococcus thermophilus LMG 18311 preprotein translocase subunit YajC YP_138736.1 202552 D 264199 CDS YP_138737.1 55820295 3163754 203019..203768 1 NC_006448.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 203768 uppS 3163754 uppS Streptococcus thermophilus LMG 18311 undecaprenyl pyrophosphate synthase YP_138737.1 203019 D 264199 CDS YP_138738.1 55820296 3164913 203781..204575 1 NC_006448.1 phosphatidate cytidylyltransferase 204575 cdsA 3164913 cdsA Streptococcus thermophilus LMG 18311 phosphatidate cytidylyltransferase YP_138738.1 203781 D 264199 CDS YP_138739.1 55820297 3164352 204592..205854 1 NC_006448.1 hypothetical protein 205854 eep 3164352 eep Streptococcus thermophilus LMG 18311 hypothetical protein YP_138739.1 204592 D 264199 CDS YP_138740.1 55820298 3164931 205925..207787 1 NC_006448.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 207787 proS 3164931 proS Streptococcus thermophilus LMG 18311 prolyl-tRNA synthetase YP_138740.1 205925 D 264199 CDS YP_138741.1 55820299 3164105 208365..210344 1 NC_006448.1 ABC transporter substrate binding/membrane-spanning protein 210344 3164105 stu0201 Streptococcus thermophilus LMG 18311 ABC transporter substrate binding/membrane-spanning protein YP_138741.1 208365 D 264199 CDS YP_138742.1 55820300 3164607 210344..211147 1 NC_006448.1 ABC transporter ATP binding protein 211147 3164607 stu0202 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_138742.1 210344 D 264199 CDS YP_138743.2 161611300 3164998 211315..211602 1 NC_006448.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 211602 groES 3164998 groES Streptococcus thermophilus LMG 18311 co-chaperonin GroES YP_138743.2 211315 D 264199 CDS YP_138744.1 55820302 3164027 211651..213270 1 NC_006448.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 213270 groEL 3164027 groEL Streptococcus thermophilus LMG 18311 molecular chaperone GroEL YP_138744.1 211651 D 264199 CDS YP_138745.1 55820303 3164025 213403..213822 1 NC_006448.1 truncated; hypothetical protein 213822 3164025 stu0205 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138745.1 213403 D 264199 CDS YP_138746.1 55820304 3163811 213829..214209 1 NC_006448.1 truncated; hypothetical protein 214209 3163811 stu0206 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138746.1 213829 D 264199 CDS YP_138747.1 55820305 3164957 214267..214485 1 NC_006448.1 truncated; hypothetical protein 214485 3164957 stu0207 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138747.1 214267 D 264199 CDS YP_138748.1 55820306 3164155 complement(214678..214905) 1 NC_006448.1 hypothetical protein 214905 3164155 stu0208 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138748.1 214678 R 264199 CDS YP_138749.1 55820307 3164727 complement(215496..215801) 1 NC_006448.1 hypothetical protein 215801 3164727 stu0209 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138749.1 215496 R 264199 CDS YP_138750.1 55820308 3165053 complement(215801..215992) 1 NC_006448.1 hypothetical protein 215992 3165053 stu0210 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138750.1 215801 R 264199 CDS YP_138751.1 55820309 3164034 complement(216313..217185) 1 NC_006448.1 ribosomal large subunit pseudouridine synthase D 217185 3164034 stu0211 Streptococcus thermophilus LMG 18311 ribosomal large subunit pseudouridine synthase D YP_138751.1 216313 R 264199 CDS YP_138752.1 55820310 3164856 217251..219578 1 NC_006448.1 penicillin-binding protein 2A 219578 pbp2A 3164856 pbp2A Streptococcus thermophilus LMG 18311 penicillin-binding protein 2A YP_138752.1 217251 D 264199 CDS YP_138753.1 55820311 3165039 219627..219779 1 NC_006448.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 219779 rpmG 3165039 rpmG Streptococcus thermophilus LMG 18311 50S ribosomal protein L33 YP_138753.1 219627 D 264199 CDS YP_138754.1 55820312 3164302 219788..219964 1 NC_006448.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 219964 secE 3164302 secE Streptococcus thermophilus LMG 18311 preprotein translocase subunit SecE YP_138754.1 219788 D 264199 CDS YP_138755.1 55820313 3164820 220161..220700 1 NC_006448.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 220700 nusG 3164820 nusG Streptococcus thermophilus LMG 18311 transcription antitermination protein NusG YP_138755.1 220161 D 264199 CDS YP_138756.1 55820314 3163836 220822..221310 1 NC_006448.1 hypothetical protein 221310 3163836 stu0216 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138756.1 220822 D 264199 CDS YP_138757.1 55820315 3164405 complement(221442..221783) 1 NC_006448.1 truncated; hypothetical protein 221783 3164405 stu0217 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138757.1 221442 R 264199 CDS YP_138758.1 55820316 3163965 complement(222036..222272) 1 NC_006448.1 truncated; hypothetical protein 222272 3163965 stu0218 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138758.1 222036 R 264199 CDS YP_138759.1 55820317 3164180 complement(222247..223011) 1 NC_006448.1 DeoR family transcriptional regulator 223011 3164180 stu0219 Streptococcus thermophilus LMG 18311 DeoR family transcriptional regulator YP_138759.1 222247 R 264199 CDS YP_138760.1 55820318 3164502 223185..225686 1 NC_006448.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 225686 leuS 3164502 leuS Streptococcus thermophilus LMG 18311 leucyl-tRNA synthetase YP_138760.1 223185 D 264199 CDS YP_138761.1 55820319 3163840 225775..225966 1 NC_006448.1 hypothetical protein 225966 3163840 stu0221 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138761.1 225775 D 264199 CDS YP_138762.1 55820320 3165221 225997..226134 1 NC_006448.1 hypothetical protein 226134 3165221 stu0222 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138762.1 225997 D 264199 CDS YP_138763.1 55820321 3165617 complement(226455..227495) 1 NC_006448.1 IS1239 transposase 227495 tnp1239 3165617 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_138763.1 226455 R 264199 CDS YP_138764.1 55820322 3164909 227640..228152 1 NC_006448.1 truncated; acyl-CoA thioesterase 228152 3164909 stu0224 Streptococcus thermophilus LMG 18311 acyl-CoA thioesterase YP_138764.1 227640 D 264199 CDS YP_138765.1 55820323 3164196 228103..228861 1 NC_006448.1 truncated; acyl-CoA thioesterase 228861 3164196 stu0225 Streptococcus thermophilus LMG 18311 acyl-CoA thioesterase YP_138765.1 228103 D 264199 CDS YP_138766.2 161611299 3164077 229155..230609 1 NC_006448.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 230609 pncB 3164077 pncB Streptococcus thermophilus LMG 18311 nicotinate phosphoribosyltransferase YP_138766.2 229155 D 264199 CDS YP_138767.1 55820325 3163948 230621..231442 1 NC_006448.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 231442 nadE 3163948 nadE Streptococcus thermophilus LMG 18311 NAD synthetase YP_138767.1 230621 D 264199 CDS YP_138768.1 55820326 3165103 231458..231898 1 NC_006448.1 hypothetical protein 231898 3165103 stu0228 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138768.1 231458 D 264199 CDS YP_138769.1 55820327 3163969 232000..233337 1 NC_006448.1 cysteine aminopeptidase 233337 pepC 3163969 pepC Streptococcus thermophilus LMG 18311 cysteine aminopeptidase YP_138769.1 232000 D 264199 CDS YP_138770.1 55820328 3164335 complement(233447..235777) 1 NC_006448.1 penicillin-binding protein 1A 235777 pbp1A 3164335 pbp1A Streptococcus thermophilus LMG 18311 penicillin-binding protein 1A YP_138770.1 233447 R 264199 CDS YP_138771.1 55820329 3163759 complement(235777..236373) 1 NC_006448.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 236373 recU 3163759 recU Streptococcus thermophilus LMG 18311 Holliday junction-specific endonuclease YP_138771.1 235777 R 264199 CDS YP_138772.1 55820330 3165108 236450..236965 1 NC_006448.1 hypothetical protein 236965 3165108 stu0232 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138772.1 236450 D 264199 CDS YP_138773.1 55820331 3164259 237074..237406 1 NC_006448.1 GpsB; guiding PBP1 shuttling; similar to DivIVA; cell division protein GpsB 237406 3164259 stu0233 Streptococcus thermophilus LMG 18311 cell division protein GpsB YP_138773.1 237074 D 264199 CDS YP_138774.1 55820332 3164379 237933..239105 1 NC_006448.1 hypothetical protein 239105 3164379 stu0234 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138774.1 237933 D 264199 CDS YP_138775.1 55820333 3165106 239108..240970 1 NC_006448.1 hypothetical protein 240970 3165106 stu0235 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138775.1 239108 D 264199 CDS YP_138776.1 55820334 3164726 241081..244176 1 NC_006448.1 ATP-dependent RNA helicase 244176 snf 3164726 snf Streptococcus thermophilus LMG 18311 ATP-dependent RNA helicase YP_138776.1 241081 D 264199 CDS YP_138777.1 55820335 3165226 244332..245048 1 NC_006448.1 hypothetical protein 245048 3165226 stu0238 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138777.1 244332 D 264199 CDS YP_138778.1 55820336 3164378 245060..246403 1 NC_006448.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 246403 murC 3164378 murC Streptococcus thermophilus LMG 18311 UDP-N-acetylmuramate--L-alanine ligase YP_138778.1 245060 D 264199 CDS YP_138779.1 55820337 3164838 246489..246956 1 NC_006448.1 acetyltransferase 246956 3164838 stu0240 Streptococcus thermophilus LMG 18311 acetyltransferase YP_138779.1 246489 D 264199 CDS YP_138780.1 55820338 3163885 247056..249032 1 NC_006448.1 aminodeoxychorismate lyase 249032 pabC 3163885 pabC Streptococcus thermophilus LMG 18311 aminodeoxychorismate lyase YP_138780.1 247056 D 264199 CDS YP_138781.1 55820339 3163879 249116..249598 1 NC_006448.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 249598 greA 3163879 greA Streptococcus thermophilus LMG 18311 transcription elongation factor GreA YP_138781.1 249116 D 264199 CDS YP_138782.1 55820340 3164816 250003..250095 1 NC_006448.1 truncated; hypothetical protein 250095 3164816 stu0243 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138782.1 250003 D 264199 CDS YP_138783.1 55820341 3164980 250142..250492 1 NC_006448.1 truncated; hypothetical protein 250492 3164980 stu0244 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138783.1 250142 D 264199 CDS YP_138784.1 55820342 3164414 complement(250548..251465) 1 NC_006448.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein 251465 3164414 stu0245 Streptococcus thermophilus LMG 18311 OxaA-like protein YP_138784.1 250548 R 264199 CDS YP_138785.1 55820343 3165600 complement(251552..251830) 1 NC_006448.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 251830 acyP 3165600 acyP Streptococcus thermophilus LMG 18311 acylphosphatase YP_138785.1 251552 R 264199 CDS YP_138786.1 55820344 3164189 251933..252670 1 NC_006448.1 rRNA methyltransferase 252670 spoU 3164189 spoU Streptococcus thermophilus LMG 18311 rRNA methyltransferase YP_138786.1 251933 D 264199 CDS YP_138787.1 55820345 3163846 252772..253266 1 NC_006448.1 hydrolase 253266 3163846 stu0248 Streptococcus thermophilus LMG 18311 hydrolase YP_138787.1 252772 D 264199 CDS YP_138788.1 55820346 3165194 253300..253989 1 NC_006448.1 hypothetical protein 253989 3165194 stu0249 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138788.1 253300 D 264199 CDS YP_138789.1 55820347 3163829 complement(254100..254396) 1 NC_006448.1 hypothetical protein 254396 3163829 stu0250 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138789.1 254100 R 264199 CDS YP_138790.1 55820348 3164509 complement(254771..255109) 1 NC_006448.1 hypothetical protein 255109 3164509 stu0251 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138790.1 254771 R 264199 CDS YP_138791.1 55820349 3164868 255284..256549 1 NC_006448.1 diaminopimelate decarboxylase 256549 lysA 3164868 lysA Streptococcus thermophilus LMG 18311 diaminopimelate decarboxylase YP_138791.1 255284 D 264199 CDS YP_138792.1 55820350 3163978 complement(256579..257118) 1 NC_006448.1 TetR/AcrR family transcriptional regulator 257118 3163978 stu0253 Streptococcus thermophilus LMG 18311 TetR/AcrR family transcriptional regulator YP_138792.1 256579 R 264199 CDS YP_138793.1 55820351 3164966 257359..257604 1 NC_006448.1 hypothetical protein 257604 3164966 stu0254 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138793.1 257359 D 264199 CDS YP_138794.1 55820352 3163834 257670..258485 1 NC_006448.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 258485 glr 3163834 glr Streptococcus thermophilus LMG 18311 glutamate racemase YP_138794.1 257670 D 264199 CDS YP_138795.1 55820353 3165007 258478..259452 1 NC_006448.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein 259452 3165007 stu0256 Streptococcus thermophilus LMG 18311 deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein YP_138795.1 258478 D 264199 CDS YP_138796.1 55820354 3164147 259434..259955 1 NC_006448.1 hypothetical protein 259955 3164147 stu0257 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138796.1 259434 D 264199 CDS YP_138797.1 55820355 3164161 259952..260434 1 NC_006448.1 hypothetical protein 260434 3164161 stu0258 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138797.1 259952 D 264199 CDS YP_138798.1 55820356 3164562 260388..261149 1 NC_006448.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 261149 xerD 3164562 xerD Streptococcus thermophilus LMG 18311 site-specific tyrosine recombinase XerD-like protein YP_138798.1 260388 D 264199 CDS YP_138799.1 55820357 3163899 261149..261862 1 NC_006448.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 261862 scpA 3163899 scpA Streptococcus thermophilus LMG 18311 segregation and condensation protein A YP_138799.1 261149 D 264199 CDS YP_138800.1 55820358 3164050 261855..262436 1 NC_006448.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 262436 scpB 3164050 scpB Streptococcus thermophilus LMG 18311 segregation and condensation protein B YP_138800.1 261855 D 264199 CDS YP_138801.1 55820359 3163869 262487..263254 1 NC_006448.1 ribosomal large subunit pseudouridine synthase B 263254 rluB 3163869 rluB Streptococcus thermophilus LMG 18311 ribosomal large subunit pseudouridine synthase B YP_138801.1 262487 D 264199 CDS YP_138802.1 55820360 3164037 263251..263502 1 NC_006448.1 hypothetical protein 263502 3164037 stu0263 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138802.1 263251 D 264199 CDS YP_138803.1 55820361 3165133 complement(263525..264964) 1 NC_006448.1 K+ transporter (Trk), membrane-spanning protein 264964 trkH1 3165133 trkH1 Streptococcus thermophilus LMG 18311 K+ transporter (Trk), membrane-spanning protein YP_138803.1 263525 R 264199 CDS YP_138804.1 55820362 3164634 complement(264971..266320) 1 NC_006448.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 266320 trkA 3164634 trkA Streptococcus thermophilus LMG 18311 potassium transporter peripheral membrane component YP_138804.1 264971 R 264199 CDS YP_138805.1 55820363 3164648 complement(266441..267481) 1 NC_006448.1 IS1239 transposase 267481 tnp1239 3164648 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_138805.1 266441 R 264199 CDS YP_138806.1 55820364 3164349 267808..268362 1 NC_006448.1 rRNA methyltransferase 268362 3164349 stu0267 Streptococcus thermophilus LMG 18311 rRNA methyltransferase YP_138806.1 267808 D 264199 CDS YP_138807.1 55820365 3164120 268596..269231 1 NC_006448.1 hypothetical protein 269231 3164120 stu0268 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138807.1 268596 D 264199 CDS YP_138808.1 55820366 3165614 269234..269884 1 NC_006448.1 hypothetical protein 269884 3165614 stu0269 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138808.1 269234 D 264199 CDS YP_138809.1 55820367 3164013 270090..270989 1 NC_006448.1 transcriptional regulator 270989 plcR 3164013 plcR Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138809.1 270090 D 264199 CDS YP_138810.1 55820368 3163911 271164..271388 1 NC_006448.1 truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 271388 3163911 stu0271 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated YP_138810.1 271164 D 264199 CDS YP_138811.1 55820369 3165612 271419..272084 1 NC_006448.1 truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272084 3165612 stu0272 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated YP_138811.1 271419 D 264199 CDS YP_138812.1 55820370 3164307 272115..272405 1 NC_006448.1 truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272405 3164307 stu0273 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated YP_138812.1 272115 D 264199 CDS YP_138813.1 55820371 3164754 272427..272834 1 NC_006448.1 truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272834 3164754 stu0274 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated YP_138813.1 272427 D 264199 CDS YP_138814.1 55820372 3164580 272840..273259 1 NC_006448.1 truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 273259 3164580 stu0275 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated YP_138814.1 272840 D 264199 CDS YP_138815.1 55820373 3164332 273367..273684 1 NC_006448.1 hypothetical protein 273684 3164332 stu0276 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138815.1 273367 D 264199 CDS YP_138816.1 55820374 3164171 complement(274171..274971) 1 NC_006448.1 truncated; urease cluster protein, truncated 274971 3164171 stu0277 Streptococcus thermophilus LMG 18311 urease cluster protein, truncated YP_138816.1 274171 R 264199 CDS YP_138817.1 55820375 3164904 275472..275987 1 NC_006448.1 urea channel 275987 ureI 3164904 ureI Streptococcus thermophilus LMG 18311 urea channel YP_138817.1 275472 D 264199 CDS YP_138818.1 55820376 3164063 276012..276314 1 NC_006448.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 276314 ureA 3164063 ureA Streptococcus thermophilus LMG 18311 urease subunit gamma YP_138818.1 276012 D 264199 CDS YP_138819.1 55820377 3163757 276326..276637 1 NC_006448.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 276637 ureB 3163757 ureB Streptococcus thermophilus LMG 18311 urease subunit beta YP_138819.1 276326 D 264199 CDS YP_138820.1 55820378 3164271 276653..278371 1 NC_006448.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 278371 ureC 3164271 ureC Streptococcus thermophilus LMG 18311 urease subunit alpha YP_138820.1 276653 D 264199 CDS YP_138821.1 55820379 3164345 278512..278964 1 NC_006448.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 278964 ureE 3164345 ureE Streptococcus thermophilus LMG 18311 urease accessory protein UreE YP_138821.1 278512 D 264199 CDS YP_138822.1 55820380 3164107 278954..279667 1 NC_006448.1 urease accessory protein 279667 ureF 3164107 ureF Streptococcus thermophilus LMG 18311 urease accessory protein YP_138822.1 278954 D 264199 CDS YP_138823.1 55820381 3164994 279697..280311 1 NC_006448.1 urease accessory protein 280311 ureG 3164994 ureG Streptococcus thermophilus LMG 18311 urease accessory protein YP_138823.1 279697 D 264199 CDS YP_138824.1 55820382 3164278 280313..281152 1 NC_006448.1 urease accessory protein 281152 ureD 3164278 ureD Streptococcus thermophilus LMG 18311 urease accessory protein YP_138824.1 280313 D 264199 CDS YP_138825.1 55820383 3164854 281156..282133 1 NC_006448.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 282133 cbiM 3164854 cbiM Streptococcus thermophilus LMG 18311 cobalt transport protein CbiM YP_138825.1 281156 D 264199 CDS YP_138826.1 55820384 3165202 282130..282909 1 NC_006448.1 ABC transporter membrane-spanning protein 282909 3165202 stu0289 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_138826.1 282130 D 264199 CDS YP_138827.1 55820385 3163993 282911..283624 1 NC_006448.1 ABC transporter ATP-binding protein 283624 3163993 stu0290 Streptococcus thermophilus LMG 18311 ABC transporter ATP-binding protein YP_138827.1 282911 D 264199 CDS YP_138828.1 55820386 3164398 283789..284637 1 NC_006448.1 ABC transporter substrate binding protein 284637 3164398 stu0291 Streptococcus thermophilus LMG 18311 ABC transporter substrate binding protein YP_138828.1 283789 D 264199 CDS YP_138829.1 55820387 3165204 284827..287718 1 NC_006448.1 non-ribosomal peptide synthetase 287718 pps 3165204 pps Streptococcus thermophilus LMG 18311 non-ribosomal peptide synthetase YP_138829.1 284827 D 264199 CDS YP_138830.1 55820388 3164423 287715..289361 1 NC_006448.1 hypothetical protein 289361 3164423 stu0293 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138830.1 287715 D 264199 CDS YP_138831.1 55820389 3164557 289387..290595 1 NC_006448.1 drug:H+ antiporter-3 (DHA3) family protein 290595 3164557 stu0294 Streptococcus thermophilus LMG 18311 drug:H+ antiporter-3 (DHA3) family protein YP_138831.1 289387 D 264199 CDS YP_138832.1 55820390 3164844 complement(290976..291170) 1 NC_006448.1 truncated; hypothetical protein 291170 3164844 stu0295 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138832.1 290976 R 264199 CDS YP_138833.1 55820391 3164921 291302..292150 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 292150 3164921 stu0296 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_138833.1 291302 D 264199 CDS YP_138834.1 55820392 3165559 292310..293212 1 NC_006448.1 ABC transporter substrate binding protein 293212 3165559 stu0297 Streptococcus thermophilus LMG 18311 ABC transporter substrate binding protein YP_138834.1 292310 D 264199 CDS YP_138835.1 55820393 3163854 293273..293755 1 NC_006448.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 293755 3163854 stu0298 Streptococcus thermophilus LMG 18311 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_138835.1 293273 D 264199 CDS YP_138836.1 55820394 3163805 293813..294178 1 NC_006448.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 294178 3163805 stu0299 Streptococcus thermophilus LMG 18311 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_138836.1 293813 D 264199 CDS YP_138837.1 55820395 3163933 294263..294646 1 NC_006448.1 truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 294646 3163933 stu0300 Streptococcus thermophilus LMG 18311 succinyl-diaminopimelic descuccinlyasadipeptidase, truncated YP_138837.1 294263 D 264199 CDS YP_138838.1 55820396 3164679 294639..295706 1 NC_006448.1 polar amino acid ABC uptake transporter ATP binding protein 295706 3164679 stu0301 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP binding protein YP_138838.1 294639 D 264199 CDS YP_138839.1 55820397 3164076 295706..296398 1 NC_006448.1 ABC transporter membrane-spanning protein 296398 3164076 stu0302 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_138839.1 295706 D 264199 CDS YP_138840.1 55820398 3165098 296521..297729 1 NC_006448.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 297729 dctA 3165098 dctA Streptococcus thermophilus LMG 18311 serine/threonine transporter SstT YP_138840.1 296521 D 264199 CDS YP_138841.1 55820399 3164114 297882..298094 1 NC_006448.1 truncated; hypothetical protein 298094 3164114 stu0304 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138841.1 297882 D 264199 CDS YP_138842.1 55820400 3164617 298127..298732 1 NC_006448.1 truncated; hypothetical protein 298732 3164617 stu0305 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138842.1 298127 D 264199 CDS YP_138843.1 55820401 3163920 298742..298945 1 NC_006448.1 truncated; hypothetical protein 298945 3163920 stu0306 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138843.1 298742 D 264199 CDS YP_138844.1 55820402 3164018 299045..299293 1 NC_006448.1 truncated; hypothetical protein 299293 3164018 stu0307 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138844.1 299045 D 264199 CDS YP_138845.1 55820403 3164623 299329..299574 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 299574 3164623 stu0308 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_138845.1 299329 D 264199 CDS YP_138846.1 55820404 3163771 299630..301036 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 301036 3163771 stu0309 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_138846.1 299630 D 264199 CDS YP_138847.1 55820405 3164907 301029..301163 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 301163 3164907 stu0310 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_138847.1 301029 D 264199 CDS YP_138848.1 55820406 3165167 301142..301681 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 301681 3165167 stu0311 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_138848.1 301142 D 264199 CDS YP_138849.1 55820407 3164919 302032..304008 1 NC_006448.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 304008 tkt 3164919 tkt Streptococcus thermophilus LMG 18311 transketolase YP_138849.1 302032 D 264199 CDS YP_138850.1 55820408 3165615 complement(304257..304928) 1 NC_006448.1 K+ transporter (Trk), NAD+ binding protein 304928 trkA2 3165615 trkA2 Streptococcus thermophilus LMG 18311 K+ transporter (Trk), NAD+ binding protein YP_138850.1 304257 R 264199 CDS YP_138851.1 55820409 3164492 complement(304968..306353) 1 NC_006448.1 K+ transporter (Trk), membrane-spanning protein 306353 trkH2 3164492 trkH2 Streptococcus thermophilus LMG 18311 K+ transporter (Trk), membrane-spanning protein YP_138851.1 304968 R 264199 CDS YP_138852.1 55820410 3164578 complement(306402..307115) 1 NC_006448.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 307115 gidB 3164578 gidB Streptococcus thermophilus LMG 18311 16S rRNA methyltransferase GidB YP_138852.1 306402 R 264199 CDS YP_138853.1 55820411 3165139 307406..307948 1 NC_006448.1 hypothetical protein 307948 3165139 stu0316 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138853.1 307406 D 264199 CDS YP_138854.1 55820412 3164368 308104..308793 1 NC_006448.1 response regulator 308793 rr01 3164368 rr01 Streptococcus thermophilus LMG 18311 response regulator YP_138854.1 308104 D 264199 CDS YP_138855.1 55820413 3164274 308790..310307 1 NC_006448.1 sensor histidine kinase 310307 hk01 3164274 hk01 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_138855.1 308790 D 264199 CDS YP_138856.2 161611298 3165572 310429..310908 1 NC_006448.1 transcriptional regulator NrdR 310908 nrdR 3165572 nrdR Streptococcus thermophilus LMG 18311 transcriptional regulator NrdR YP_138856.2 310429 D 264199 CDS YP_138857.1 55820415 3164876 310905..312080 1 NC_006448.1 chromosome replication initiation / membrane attachment protein DnaB 312080 dnaB 3164876 dnaB Streptococcus thermophilus LMG 18311 chromosome replication initiation / membrane attachment protein DnaB YP_138857.1 310905 D 264199 CDS YP_138858.1 55820416 3163768 312084..312986 1 NC_006448.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 312986 dnaI 3163768 dnaI Streptococcus thermophilus LMG 18311 primosomal protein DnaI YP_138858.1 312084 D 264199 CDS YP_138859.1 55820417 3164244 313092..314402 1 NC_006448.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 314402 engA 3164244 engA Streptococcus thermophilus LMG 18311 GTP-binding protein EngA YP_138859.1 313092 D 264199 CDS YP_138860.1 55820418 3165097 complement(315589..317178) 1 NC_006448.1 peptide-2 ABC transporter ATP binding/membrane-spanning protein 317178 3165097 stu0324 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein YP_138860.1 315589 R 264199 CDS YP_138861.1 55820419 3163767 complement(317162..317950) 1 NC_006448.1 hypothetical protein 317950 3163767 stu0325 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138861.1 317162 R 264199 CDS YP_138862.1 55820420 3164273 318122..319330 1 NC_006448.1 IS1191 transposase 319330 tnp1191 3164273 tnp1191 Streptococcus thermophilus LMG 18311 IS1191 transposase YP_138862.1 318122 D 264199 CDS YP_138863.1 55820421 3164212 complement(319377..319610) 1 NC_006448.1 hypothetical protein 319610 3164212 stu0328 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138863.1 319377 R 264199 CDS YP_138864.2 161611297 3164960 complement(319973..321250) 1 NC_006448.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 321250 serS 3164960 serS Streptococcus thermophilus LMG 18311 seryl-tRNA synthetase YP_138864.2 319973 R 264199 CDS YP_138865.1 55820423 3164402 complement(321459..321833) 1 NC_006448.1 hypothetical protein 321833 3164402 stu0330 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138865.1 321459 R 264199 CDS YP_138866.1 55820424 3164377 complement(321912..322823) 1 NC_006448.1 mannose PTS system component IID 322823 manN 3164377 manN Streptococcus thermophilus LMG 18311 mannose PTS system component IID YP_138866.1 321912 R 264199 CDS YP_138867.1 55820425 3164399 complement(322838..323665) 1 NC_006448.1 mannose PTS system component IIC 323665 manM 3164399 manM Streptococcus thermophilus LMG 18311 mannose PTS system component IIC YP_138867.1 322838 R 264199 CDS YP_138868.1 55820426 3164692 complement(323733..324725) 1 NC_006448.1 mannose PTS system component IIAB 324725 manL 3164692 manL Streptococcus thermophilus LMG 18311 mannose PTS system component IIAB YP_138868.1 323733 R 264199 CDS YP_138869.1 55820427 3164163 325101..325832 1 NC_006448.1 hypothetical protein 325832 3164163 stu0334 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138869.1 325101 D 264199 CDS YP_138870.1 55820428 3164208 complement(325877..326677) 1 NC_006448.1 hypothetical protein 326677 3164208 stu0335 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138870.1 325877 R 264199 CDS YP_138871.1 55820429 3164084 326897..328318 1 NC_006448.1 hypothetical protein 328318 3164084 stu0336 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138871.1 326897 D 264199 CDS YP_138872.1 55820430 3163982 328590..329033 1 NC_006448.1 hypothetical protein 329033 3163982 stu0337 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138872.1 328590 D 264199 CDS YP_138873.1 55820431 3164432 329026..329547 1 NC_006448.1 acetyltransferase 329547 3164432 stu0338 Streptococcus thermophilus LMG 18311 acetyltransferase YP_138873.1 329026 D 264199 CDS YP_138874.1 55820432 3165176 329556..330782 1 NC_006448.1 transcriptional regulator 330782 3165176 stu0339 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138874.1 329556 D 264199 CDS YP_138875.1 55820433 3165151 330905..331396 1 NC_006448.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 331396 3165151 stu0340 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138875.1 330905 D 264199 CDS YP_138876.1 55820434 3164418 331462..332649 1 NC_006448.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 332649 nusA 3164418 nusA Streptococcus thermophilus LMG 18311 transcription elongation factor NusA YP_138876.1 331462 D 264199 CDS YP_138877.1 55820435 3164701 332667..332966 1 NC_006448.1 hypothetical protein 332966 3164701 stu0342 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138877.1 332667 D 264199 CDS YP_138878.1 55820436 3164309 332959..333261 1 NC_006448.1 hypothetical protein 333261 3164309 stu0343 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138878.1 332959 D 264199 CDS YP_138879.1 55820437 3164860 333280..336111 1 NC_006448.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 336111 infB 3164860 infB Streptococcus thermophilus LMG 18311 translation initiation factor IF-2 YP_138879.1 333280 D 264199 CDS YP_138880.1 55820438 3163800 336205..336558 1 NC_006448.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 336558 rbfA 3163800 rbfA Streptococcus thermophilus LMG 18311 ribosome-binding factor A YP_138880.1 336205 D 264199 CDS YP_138881.1 55820439 3164270 336623..336916 1 NC_006448.1 hypothetical protein 336916 3164270 stu0346 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138881.1 336623 D 264199 CDS YP_138882.1 55820440 3164953 336900..337079 1 NC_006448.1 hypothetical protein 337079 3164953 stu0347 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138882.1 336900 D 264199 CDS YP_138883.1 55820441 3164593 337454..338713 1 NC_006448.1 peptidoglycan branched peptide synthesis protein 338713 murO 3164593 murO Streptococcus thermophilus LMG 18311 peptidoglycan branched peptide synthesis protein YP_138883.1 337454 D 264199 CDS YP_138884.1 55820442 3164064 complement(338782..340227) 1 NC_006448.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 340227 murE 3164064 murE Streptococcus thermophilus LMG 18311 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_138884.1 338782 R 264199 CDS YP_138885.1 55820443 3164763 340322..341953 1 NC_006448.1 polysaccharide transporter 341953 3164763 stu0350 Streptococcus thermophilus LMG 18311 polysaccharide transporter YP_138885.1 340322 D 264199 CDS YP_138886.1 55820444 3164297 341977..342486 1 NC_006448.1 truncated; Ca2+, Mn2+-P-type ATPase, truncated 342486 3164297 stu0351 Streptococcus thermophilus LMG 18311 Ca2+, Mn2+-P-type ATPase, truncated YP_138886.1 341977 D 264199 CDS YP_138887.1 55820445 3164591 342893..343987 1 NC_006448.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 343987 metB1 3164591 metB1 Streptococcus thermophilus LMG 18311 cystathionine gamma-synthase YP_138887.1 342893 D 264199 CDS YP_138888.1 55820446 3164786 343956..345161 1 NC_006448.1 aminotransferase 345161 3164786 stu0353 Streptococcus thermophilus LMG 18311 aminotransferase YP_138888.1 343956 D 264199 CDS YP_138889.1 55820447 3163988 345445..345720 1 NC_006448.1 hypothetical protein 345720 3163988 stu0354 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138889.1 345445 D 264199 CDS YP_138890.1 55820448 3165010 345850..346479 1 NC_006448.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 346479 upp 3165010 upp Streptococcus thermophilus LMG 18311 uracil phosphoribosyltransferase YP_138890.1 345850 D 264199 CDS YP_138891.1 55820449 3164125 346617..347207 1 NC_006448.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 347207 clpP 3164125 clpP Streptococcus thermophilus LMG 18311 ATP-dependent Clp protease proteolytic subunit YP_138891.1 346617 D 264199 CDS YP_138892.1 55820450 3165003 347294..347743 1 NC_006448.1 hypothetical protein 347743 3165003 stu0357 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138892.1 347294 D 264199 CDS YP_138893.1 55820451 3165004 347736..348017 1 NC_006448.1 hypothetical protein 348017 3165004 stu0358 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138893.1 347736 D 264199 CDS YP_138894.1 55820452 3164649 348174..349349 1 NC_006448.1 branched-chain amino acid ABC uptake transporter substrate-binding protein 349349 livJ 3164649 livJ Streptococcus thermophilus LMG 18311 branched-chain amino acid ABC uptake transporter substrate-binding protein YP_138894.1 348174 D 264199 CDS YP_138895.1 55820453 3164312 349393..350277 1 NC_006448.1 branched-chain amino acid ABC uptake transporter membrane-spanning protein 350277 livH 3164312 livH Streptococcus thermophilus LMG 18311 branched-chain amino acid ABC uptake transporter membrane-spanning protein YP_138895.1 349393 D 264199 CDS YP_138896.1 55820454 3163986 350281..351231 1 NC_006448.1 branched-chain amino acid ABC uptake transporter membrane-spanning protein 351231 livM 3163986 livM Streptococcus thermophilus LMG 18311 branched-chain amino acid ABC uptake transporter membrane-spanning protein YP_138896.1 350281 D 264199 CDS YP_138897.1 55820455 3164314 351234..351998 1 NC_006448.1 branched-chain amino acid ABC uptake transporter ATP binding protein 351998 livG 3164314 livG Streptococcus thermophilus LMG 18311 branched-chain amino acid ABC uptake transporter ATP binding protein YP_138897.1 351234 D 264199 CDS YP_138898.1 55820456 3164553 351998..352708 1 NC_006448.1 branched chain amino acid ABC uptake transporter ATP binding protein 352708 livF 3164553 livF Streptococcus thermophilus LMG 18311 branched chain amino acid ABC uptake transporter ATP binding protein YP_138898.1 351998 D 264199 CDS YP_138899.1 55820457 3164734 352862..353281 1 NC_006448.1 truncated; acetoin utilization protein, truncated 353281 3164734 stu0364 Streptococcus thermophilus LMG 18311 acetoin utilization protein, truncated YP_138899.1 352862 D 264199 CDS YP_138900.1 55820458 3164158 353226..353504 1 NC_006448.1 truncated; acetoin utilization protein, truncated 353504 3164158 stu0365 Streptococcus thermophilus LMG 18311 acetoin utilization protein, truncated YP_138900.1 353226 D 264199 CDS YP_138901.1 55820459 3164849 complement(353671..354603) 1 NC_006448.1 cysteine synthase 354603 cysM1 3164849 cysM1 Streptococcus thermophilus LMG 18311 cysteine synthase YP_138901.1 353671 R 264199 CDS YP_138902.1 55820460 3164669 complement(354699..355325) 1 NC_006448.1 hypothetical protein 355325 3164669 stu0367 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138902.1 354699 R 264199 CDS YP_138903.1 55820461 3165094 355380..356699 1 NC_006448.1 late competence protein required for DNA uptake 356699 comFA 3165094 comFA Streptococcus thermophilus LMG 18311 late competence protein required for DNA uptake YP_138903.1 355380 D 264199 CDS YP_138904.1 55820462 3164704 356674..357342 1 NC_006448.1 late competence protein 357342 comFC 3164704 comFC Streptococcus thermophilus LMG 18311 late competence protein YP_138904.1 356674 D 264199 CDS YP_138905.1 55820463 3164975 357421..357969 1 NC_006448.1 ribosomal protein S30AE family protein 357969 3164975 stu0370 Streptococcus thermophilus LMG 18311 ribosomal protein S30AE family protein YP_138905.1 357421 D 264199 CDS YP_138906.1 55820464 3164072 363881..364813 1 NC_006448.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 364813 ppaC 3164072 ppaC Streptococcus thermophilus LMG 18311 manganese-dependent inorganic pyrophosphatase YP_138906.1 363881 D 264199 CDS YP_138907.1 55820465 3164852 364867..365526 1 NC_006448.1 hypothetical protein 365526 3164852 stu0373 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138907.1 364867 D 264199 CDS YP_138908.1 55820466 3163918 complement(365556..366089) 1 NC_006448.1 hypothetical protein 366089 3163918 stu0374 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138908.1 365556 R 264199 CDS YP_138909.1 55820467 3164463 complement(366160..366936) 1 NC_006448.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 366936 recX 3164463 recX Streptococcus thermophilus LMG 18311 recombination regulator RecX YP_138909.1 366160 R 264199 CDS YP_138910.1 55820468 3164242 366971..368335 1 NC_006448.1 TrmA family tRNA methyltransferase 368335 3164242 stu0376 Streptococcus thermophilus LMG 18311 TrmA family tRNA methyltransferase YP_138910.1 366971 D 264199 CDS YP_138911.1 55820469 3164565 368434..369426 1 NC_006448.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 369426 asnA 3164565 asnA Streptococcus thermophilus LMG 18311 asparagine synthetase AsnA YP_138911.1 368434 D 264199 CDS YP_138912.1 55820470 3164322 complement(369578..370936) 1 NC_006448.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 370936 lysC 3164322 lysC Streptococcus thermophilus LMG 18311 aspartate kinase YP_138912.1 369578 R 264199 CDS YP_138913.1 55820471 3164308 371068..371706 1 NC_006448.1 beta-phosphoglucomutase 371706 3164308 stu0379 Streptococcus thermophilus LMG 18311 beta-phosphoglucomutase YP_138913.1 371068 D 264199 CDS YP_138914.1 55820472 3164046 371919..372710 1 NC_006448.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 372710 phaB 3164046 phaB Streptococcus thermophilus LMG 18311 enoyl-CoA hydratase YP_138914.1 371919 D 264199 CDS YP_138915.1 55820473 3164787 372814..373248 1 NC_006448.1 MarR family transcriptional regulator 373248 3164787 stu0381 Streptococcus thermophilus LMG 18311 MarR family transcriptional regulator YP_138915.1 372814 D 264199 CDS YP_138916.1 55820474 3164049 373248..374210 1 NC_006448.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 374210 fabH 3164049 fabH Streptococcus thermophilus LMG 18311 3-oxoacyl-ACP synthase YP_138916.1 373248 D 264199 CDS YP_138917.1 55820475 3165585 374274..374498 1 NC_006448.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 374498 acpP 3165585 acpP Streptococcus thermophilus LMG 18311 acyl carrier protein YP_138917.1 374274 D 264199 CDS YP_138918.1 55820476 3164202 374604..375569 1 NC_006448.1 trans-2-enoyl-ACP reductase II 375569 fabK 3164202 fabK Streptococcus thermophilus LMG 18311 trans-2-enoyl-ACP reductase II YP_138918.1 374604 D 264199 CDS YP_138919.1 55820477 3164516 375586..376512 1 NC_006448.1 ACP S-malonyltransferase 376512 fabD 3164516 fabD Streptococcus thermophilus LMG 18311 ACP S-malonyltransferase YP_138919.1 375586 D 264199 CDS YP_138920.1 55820478 3165100 376525..377259 1 NC_006448.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 377259 fabG 3165100 fabG Streptococcus thermophilus LMG 18311 3-ketoacyl-ACP reductase YP_138920.1 376525 D 264199 CDS YP_138921.1 55820479 3164900 377321..378553 1 NC_006448.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 378553 fabF 3164900 fabF Streptococcus thermophilus LMG 18311 3-oxoacyl-ACP synthase YP_138921.1 377321 D 264199 CDS YP_138922.1 55820480 3163779 378557..379045 1 NC_006448.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 379045 accB 3163779 accB Streptococcus thermophilus LMG 18311 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_138922.1 378557 D 264199 CDS YP_138923.1 55820481 3164081 379042..379467 1 NC_006448.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 379467 fabZ 3164081 fabZ Streptococcus thermophilus LMG 18311 (3R)-hydroxymyristoyl-ACP dehydratase YP_138923.1 379042 D 264199 CDS YP_138924.2 161611296 3165142 379587..380957 1 NC_006448.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 380957 accC 3165142 accC Streptococcus thermophilus LMG 18311 acetyl-CoA carboxylase biotin carboxylase subunit YP_138924.2 379587 D 264199 CDS YP_138925.1 55820483 3164019 380963..381829 1 NC_006448.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 381829 accD 3164019 accD Streptococcus thermophilus LMG 18311 acetyl-CoA carboxylase subunit beta YP_138925.1 380963 D 264199 CDS YP_138926.1 55820484 3163987 381826..382596 1 NC_006448.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 382596 accA 3163987 accA Streptococcus thermophilus LMG 18311 acetyl-CoA carboxylase subunit alpha YP_138926.1 381826 D 264199 CDS YP_138927.1 55820485 3164501 complement(382627..383109) 1 NC_006448.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 383109 luxS 3164501 luxS Streptococcus thermophilus LMG 18311 S-ribosylhomocysteinase YP_138927.1 382627 R 264199 CDS YP_138928.1 55820486 3164577 383256..383492 1 NC_006448.1 truncated; type I restriction modification system specificity subunit, truncated 383492 3164577 stu0395 Streptococcus thermophilus LMG 18311 type I restriction modification system specificity subunit, truncated YP_138928.1 383256 D 264199 CDS YP_138929.1 55820487 3164117 383643..384323 1 NC_006448.1 IS1216 transposase 384323 tnp1216 3164117 tnp1216 Streptococcus thermophilus LMG 18311 IS1216 transposase YP_138929.1 383643 D 264199 CDS YP_138930.1 55820488 3164599 384737..386344 1 NC_006448.1 hypothetical protein 386344 3164599 stu0397 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138930.1 384737 D 264199 CDS YP_138931.1 55820489 3164845 complement(386673..387212) 1 NC_006448.1 truncated; hypothetical protein 387212 3164845 stu0398 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138931.1 386673 R 264199 CDS YP_138932.1 55820490 3164151 387770..388516 1 NC_006448.1 transcriptional repressor 388516 fruR 3164151 fruR Streptococcus thermophilus LMG 18311 transcriptional repressor YP_138932.1 387770 D 264199 CDS YP_138933.1 55820491 3165621 388513..389424 1 NC_006448.1 fructose-1-phosphate kinase 389424 fruB 3165621 fruB Streptococcus thermophilus LMG 18311 fructose-1-phosphate kinase YP_138933.1 388513 D 264199 CDS YP_138934.1 55820492 3164895 389454..390167 1 NC_006448.1 truncated; fructose PTS system component IIABC, truncated 390167 3164895 stu0401 Streptococcus thermophilus LMG 18311 fructose PTS system component IIABC, truncated YP_138934.1 389454 D 264199 CDS YP_138935.1 55820493 3164457 390164..390673 1 NC_006448.1 truncated; fructose PTS system component IIABC, truncated 390673 3164457 stu0405 Streptococcus thermophilus LMG 18311 fructose PTS system component IIABC, truncated YP_138935.1 390164 D 264199 CDS YP_138936.1 55820494 3164116 390728..391087 1 NC_006448.1 truncated; fructose PTS system component IIABC, truncated 391087 3164116 stu0406 Streptococcus thermophilus LMG 18311 fructose PTS system component IIABC, truncated YP_138936.1 390728 D 264199 CDS YP_138937.1 55820495 3163761 391080..391397 1 NC_006448.1 truncated; fructose PTS system component IIABC, truncated 391397 3163761 stu0407 Streptococcus thermophilus LMG 18311 fructose PTS system component IIABC, truncated YP_138937.1 391080 D 264199 CDS YP_138938.1 55820496 3164765 391547..392899 1 NC_006448.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 392899 gor 3164765 gor Streptococcus thermophilus LMG 18311 glutathione reductase YP_138938.1 391547 D 264199 CDS YP_138939.1 55820497 3164357 complement(393001..394257) 1 NC_006448.1 folylpolyglutamate synthase / dihydrofolate synthase 394257 folC1 3164357 folC1 Streptococcus thermophilus LMG 18311 folylpolyglutamate synthase / dihydrofolate synthase YP_138939.1 393001 R 264199 CDS YP_138940.1 55820498 3164609 complement(394303..394845) 1 NC_006448.1 hypothetical protein 394845 3164609 stu0410 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138940.1 394303 R 264199 CDS YP_138941.1 55820499 3164950 394954..396099 1 NC_006448.1 aminotransferase 396099 nifS2 3164950 nifS2 Streptococcus thermophilus LMG 18311 aminotransferase YP_138941.1 394954 D 264199 CDS YP_138942.1 55820500 3164341 396154..397377 1 NC_006448.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 397377 thiI 3164341 thiI Streptococcus thermophilus LMG 18311 thiamine biosynthesis protein ThiI YP_138942.1 396154 D 264199 CDS YP_138943.1 55820501 3164504 397483..398994 1 NC_006448.1 glycosyltransferase teichoic acid biosynthesis protein 398994 3164504 stu0413 Streptococcus thermophilus LMG 18311 glycosyltransferase teichoic acid biosynthesis protein YP_138943.1 397483 D 264199 CDS YP_138944.1 55820502 3163905 398987..400306 1 NC_006448.1 hypothetical protein 400306 3163905 stu0414 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138944.1 398987 D 264199 CDS YP_138945.1 55820503 3163742 400619..400846 1 NC_006448.1 truncated; hypothetical protein 400846 3163742 stu0416 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138945.1 400619 D 264199 CDS YP_138946.2 161611295 3163866 401075..401389 1 NC_006448.1 50S ribosomal protein L21 401389 rplU 3163866 rplU Streptococcus thermophilus LMG 18311 50S ribosomal protein L21 YP_138946.2 401075 D 264199 CDS YP_138947.1 55820505 3164622 401426..401716 1 NC_006448.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 401716 rpmA 3164622 rpmA Streptococcus thermophilus LMG 18311 50S ribosomal protein L27 YP_138947.1 401426 D 264199 CDS YP_138948.1 55820506 3164621 401775..402302 1 NC_006448.1 truncated; acetyltransferase 402302 3164621 stu0419 Streptococcus thermophilus LMG 18311 acetyltransferase YP_138948.1 401775 D 264199 CDS YP_138949.1 55820507 3165143 402202..402471 1 NC_006448.1 truncated; acetyltransferase 402471 3165143 stu0420 Streptococcus thermophilus LMG 18311 acetyltransferase YP_138949.1 402202 D 264199 CDS YP_138950.1 55820508 3164381 402672..403046 1 NC_006448.1 hypothetical protein 403046 3164381 stu0421 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138950.1 402672 D 264199 CDS YP_138951.1 55820509 3165206 403048..403260 1 NC_006448.1 truncated; hypothetical protein 403260 3165206 stu0422 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138951.1 403048 D 264199 CDS YP_138952.1 55820510 3165129 403253..403891 1 NC_006448.1 truncated; hypothetical protein 403891 3165129 stu0423 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138952.1 403253 D 264199 CDS YP_138953.1 55820511 3164650 403952..404719 1 NC_006448.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 404719 dapB 3164650 dapB Streptococcus thermophilus LMG 18311 dihydrodipicolinate reductase YP_138953.1 403952 D 264199 CDS YP_138954.1 55820512 3163884 404716..405924 1 NC_006448.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 405924 papL 3163884 papL Streptococcus thermophilus LMG 18311 tRNA CCA-pyrophosphorylase YP_138954.1 404716 D 264199 CDS YP_138955.1 55820513 3164748 406002..407882 1 NC_006448.1 ABC transporter ATP-binding protein 407882 3164748 stu0426 Streptococcus thermophilus LMG 18311 ABC transporter ATP-binding protein YP_138955.1 406002 D 264199 CDS YP_138956.1 55820514 3165199 complement(407964..408467) 1 NC_006448.1 hypothetical protein 408467 3165199 stu0427 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138956.1 407964 R 264199 CDS YP_138957.1 55820515 3164747 complement(408544..409230) 1 NC_006448.1 MutT/nudix family protein 409230 3164747 stu0428 Streptococcus thermophilus LMG 18311 MutT/nudix family protein YP_138957.1 408544 R 264199 CDS YP_138958.1 55820516 3164613 complement(409360..410466) 1 NC_006448.1 transcriptional regulator 410466 nadR 3164613 nadR Streptococcus thermophilus LMG 18311 transcriptional regulator YP_138958.1 409360 R 264199 CDS YP_138959.1 55820517 3164350 410792..412162 1 NC_006448.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 412162 gdhA 3164350 gdhA Streptococcus thermophilus LMG 18311 glutamate dehydrogenase YP_138959.1 410792 D 264199 CDS YP_138960.1 55820518 3165196 412421..412831 1 NC_006448.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 412831 defA 3165196 defA Streptococcus thermophilus LMG 18311 peptide deformylase YP_138960.1 412421 D 264199 CDS YP_138961.1 55820519 3164682 413023..413466 1 NC_006448.1 MarR family transcriptional regulator 413466 3164682 stu0432 Streptococcus thermophilus LMG 18311 MarR family transcriptional regulator YP_138961.1 413023 D 264199 CDS YP_138962.1 55820520 3164659 413470..415284 1 NC_006448.1 multidrug ABC exporter ATP binding/membrane-spanning protein 415284 lmrA1 3164659 lmrA1 Streptococcus thermophilus LMG 18311 multidrug ABC exporter ATP binding/membrane-spanning protein YP_138962.1 413470 D 264199 CDS YP_138963.1 55820521 3164651 415274..417052 1 NC_006448.1 multidrug ABC exporter ATP binding/membrane-spanning protein 417052 lmrA2 3164651 lmrA2 Streptococcus thermophilus LMG 18311 multidrug ABC exporter ATP binding/membrane-spanning protein YP_138963.1 415274 D 264199 CDS YP_138964.1 55820522 3164664 417208..417456 1 NC_006448.1 hypothetical protein 417456 3164664 stu0435 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138964.1 417208 D 264199 CDS YP_138965.1 55820523 3164796 417952..418668 1 NC_006448.1 truncated; sensor histidine kinase, uncoupled, truncated 418668 3164796 stu0437 Streptococcus thermophilus LMG 18311 sensor histidine kinase, uncoupled, truncated YP_138965.1 417952 D 264199 CDS YP_138966.1 55820524 3164247 419000..419737 1 NC_006448.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 419737 pyrH 3164247 pyrH Streptococcus thermophilus LMG 18311 uridylate kinase YP_138966.1 419000 D 264199 CDS YP_138967.1 55820525 3164839 419752..420309 1 NC_006448.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 420309 frr 3164839 frr Streptococcus thermophilus LMG 18311 ribosome recycling factor YP_138967.1 419752 D 264199 CDS YP_138968.1 55820526 3164794 420358..421257 1 NC_006448.1 hypothetical protein 421257 3164794 stu0440 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138968.1 420358 D 264199 CDS YP_138969.1 55820527 3164296 421266..421481 1 NC_006448.1 hypothetical protein 421481 3164296 stu0441 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138969.1 421266 D 264199 CDS YP_138970.1 55820528 3163984 421722..423170 1 NC_006448.1 glucan-binding protein B 423170 pcsB 3163984 pcsB Streptococcus thermophilus LMG 18311 glucan-binding protein B YP_138970.1 421722 D 264199 CDS YP_138971.1 55820529 3164696 423413..423928 1 NC_006448.1 truncated; surface immunogenic protein, truncated 423928 3164696 stu0446 Streptococcus thermophilus LMG 18311 surface immunogenic protein, truncated YP_138971.1 423413 D 264199 CDS YP_138972.1 55820530 3164885 424008..425069 1 NC_006448.1 phosphate starvation-induced protein 425069 phoH 3164885 phoH Streptococcus thermophilus LMG 18311 phosphate starvation-induced protein YP_138972.1 424008 D 264199 CDS YP_138973.1 55820531 3163942 426277..426690 1 NC_006448.1 hypothetical protein 426690 3163942 stu0448 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138973.1 426277 D 264199 CDS YP_138974.1 55820532 3164700 427161..427367 1 NC_006448.1 hypothetical protein 427367 3164700 stu0449 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138974.1 427161 D 264199 CDS YP_138975.1 55820533 3164685 427364..427771 1 NC_006448.1 hypothetical protein 427771 3164685 stu0450 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138975.1 427364 D 264199 CDS YP_138976.1 55820534 3165177 427965..429968 1 NC_006448.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 429968 metG 3165177 metG Streptococcus thermophilus LMG 18311 methionyl-tRNA synthetase YP_138976.1 427965 D 264199 CDS YP_138977.1 55820535 3165029 complement(430246..431148) 1 NC_006448.1 LysR family transcriptional regulator 431148 3165029 stu0452 Streptococcus thermophilus LMG 18311 LysR family transcriptional regulator YP_138977.1 430246 R 264199 CDS YP_138978.1 55820536 3164447 432356..433399 1 NC_006448.1 competence protein, transcription factor 433399 coiA 3164447 coiA Streptococcus thermophilus LMG 18311 competence protein, transcription factor YP_138978.1 432356 D 264199 CDS YP_138979.1 55820537 3164705 433410..435215 1 NC_006448.1 oligopeptidase 435215 pepB 3164705 pepB Streptococcus thermophilus LMG 18311 oligopeptidase YP_138979.1 433410 D 264199 CDS YP_138980.1 55820538 3164738 435398..436105 1 NC_006448.1 methyltransferase 436105 3164738 stu0455 Streptococcus thermophilus LMG 18311 methyltransferase YP_138980.1 435398 D 264199 CDS YP_138981.1 55820539 3164369 436167..437282 1 NC_006448.1 protease maturation protein 437282 prtM 3164369 prtM Streptococcus thermophilus LMG 18311 protease maturation protein YP_138981.1 436167 D 264199 CDS YP_138982.1 55820540 3164962 437624..440242 1 NC_006448.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 440242 alaS 3164962 alaS Streptococcus thermophilus LMG 18311 alanyl-tRNA synthetase YP_138982.1 437624 D 264199 CDS YP_138983.1 55820541 3164087 440404..440625 1 NC_006448.1 truncated; cell wall protein precursor, choline binding protein, truncated 440625 3164087 stu0458 Streptococcus thermophilus LMG 18311 cell wall protein precursor, choline binding protein, truncated YP_138983.1 440404 D 264199 CDS YP_138984.1 55820542 3164720 440656..441279 1 NC_006448.1 truncated; cell wall protein precursor, choline binding protein, truncated 441279 3164720 stu0459 Streptococcus thermophilus LMG 18311 cell wall protein precursor, choline binding protein, truncated YP_138984.1 440656 D 264199 CDS YP_138985.1 55820543 3164342 441406..441669 1 NC_006448.1 truncated; cell wall protein precursor, choline binding protein, truncated 441669 3164342 stu0460 Streptococcus thermophilus LMG 18311 cell wall protein precursor, choline binding protein, truncated YP_138985.1 441406 D 264199 CDS YP_138986.1 55820544 3164119 441949..442938 1 NC_006448.1 cell wall protein, choline binding protein 442938 cbpD3 3164119 cbpD3 Streptococcus thermophilus LMG 18311 cell wall protein, choline binding protein YP_138986.1 441949 D 264199 CDS YP_138987.1 55820545 3164193 443071..443859 1 NC_006448.1 hypothetical protein 443859 3164193 stu0462 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138987.1 443071 D 264199 CDS YP_138988.1 55820546 3164353 443869..445050 1 NC_006448.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; transaminase 445050 aspC3 3164353 aspC3 Streptococcus thermophilus LMG 18311 transaminase YP_138988.1 443869 D 264199 CDS YP_138989.1 55820547 3165169 445179..446201 1 NC_006448.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 446201 argC 3165169 argC Streptococcus thermophilus LMG 18311 N-acetyl-gamma-glutamyl-phosphate reductase YP_138989.1 445179 D 264199 CDS YP_138990.1 55820548 3164371 446230..447423 1 NC_006448.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 447423 argJ 3164371 argJ Streptococcus thermophilus LMG 18311 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_138990.1 446230 D 264199 CDS YP_138991.1 55820549 3164069 447450..448187 1 NC_006448.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 448187 argB 3164069 argB Streptococcus thermophilus LMG 18311 acetylglutamate kinase YP_138991.1 447450 D 264199 CDS YP_138992.1 55820550 3164630 448191..449321 1 NC_006448.1 acetylornithine aminotransferase 449321 argD 3164630 argD Streptococcus thermophilus LMG 18311 acetylornithine aminotransferase YP_138992.1 448191 D 264199 CDS YP_138993.1 55820551 3164713 complement(449362..450138) 1 NC_006448.1 hypothetical protein 450138 3164713 stu0468 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138993.1 449362 R 264199 CDS YP_138994.1 55820552 3164495 450413..451699 1 NC_006448.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 451699 hom 3164495 hom Streptococcus thermophilus LMG 18311 homoserine dehydrogenase YP_138994.1 450413 D 264199 CDS YP_138995.1 55820553 3165224 451783..452643 1 NC_006448.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 452643 thrB 3165224 thrB Streptococcus thermophilus LMG 18311 homoserine kinase YP_138995.1 451783 D 264199 CDS YP_138996.1 55820554 3164996 452591..453520 1 NC_006448.1 chloramphenicol-sensitivity protein (RarD) family protein 453520 3164996 stu0471 Streptococcus thermophilus LMG 18311 chloramphenicol-sensitivity protein (RarD) family protein YP_138996.1 452591 D 264199 CDS YP_138997.1 55820555 3164859 453702..454250 1 NC_006448.1 hypothetical protein 454250 3164859 stu0472 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138997.1 453702 D 264199 CDS YP_138998.1 55820556 3165150 454385..454588 1 NC_006448.1 hypothetical protein 454588 3165150 stu0473 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138998.1 454385 D 264199 CDS YP_138999.1 55820557 3164286 455058..455366 1 NC_006448.1 truncated; hypothetical protein 455366 3164286 stu0474 Streptococcus thermophilus LMG 18311 hypothetical protein YP_138999.1 455058 D 264199 CDS YP_139000.1 55820558 3164185 455350..455661 1 NC_006448.1 truncated; hypothetical protein 455661 3164185 stu0475 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139000.1 455350 D 264199 CDS YP_139001.1 55820559 3164126 455702..456007 1 NC_006448.1 acetyltransferase 456007 3164126 stu0476 Streptococcus thermophilus LMG 18311 acetyltransferase YP_139001.1 455702 D 264199 CDS YP_139002.2 161611294 3164306 456238..458889 1 NC_006448.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 458889 valS 3164306 valS Streptococcus thermophilus LMG 18311 valyl-tRNA synthetase YP_139002.2 456238 D 264199 CDS YP_139003.1 55820561 3164846 459066..459263 1 NC_006448.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 459263 atpE 3164846 atpE Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit C YP_139003.1 459066 D 264199 CDS YP_139004.1 55820562 3164386 459298..460005 1 NC_006448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 460005 atpB 3164386 atpB Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit A YP_139004.1 459298 D 264199 CDS YP_139005.1 55820563 3163864 460026..460523 1 NC_006448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 460523 atpF 3163864 atpF Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit B YP_139005.1 460026 D 264199 CDS YP_139006.1 55820564 3164940 460523..461059 1 NC_006448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 461059 atpH 3164940 atpH Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit delta YP_139006.1 460523 D 264199 CDS YP_139007.1 55820565 3164952 461075..462580 1 NC_006448.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 462580 atpA 3164952 atpA Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit alpha YP_139007.1 461075 D 264199 CDS YP_139008.1 55820566 3165544 462599..463477 1 NC_006448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 463477 atpG 3165544 atpG Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit gamma YP_139008.1 462599 D 264199 CDS YP_139009.1 55820567 3165545 463554..464960 1 NC_006448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 464960 atpD 3165545 atpD Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit beta YP_139009.1 463554 D 264199 CDS YP_139010.1 55820568 3164245 464973..465419 1 NC_006448.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 465419 atpC 3164245 atpC Streptococcus thermophilus LMG 18311 ATP synthase F0F1 subunit epsilon YP_139010.1 464973 D 264199 CDS YP_139011.1 55820569 3164082 465656..466951 1 NC_006448.1 cell division protein 466951 ftsW 3164082 ftsW Streptococcus thermophilus LMG 18311 cell division protein YP_139011.1 465656 D 264199 CDS YP_139012.1 55820570 3163862 467189..468385 1 NC_006448.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 468385 tuf 3163862 tuf Streptococcus thermophilus LMG 18311 elongation factor Tu YP_139012.1 467189 D 264199 CDS YP_139013.1 55820571 3164943 468634..469392 1 NC_006448.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 469392 tpiA 3164943 tpiA Streptococcus thermophilus LMG 18311 triosephosphate isomerase YP_139013.1 468634 D 264199 CDS YP_139014.1 55820572 3164496 469630..470259 1 NC_006448.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 470259 tmk 3164496 tmk Streptococcus thermophilus LMG 18311 thymidylate kinase YP_139014.1 469630 D 264199 CDS YP_139015.1 55820573 3165189 470268..471143 1 NC_006448.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 471143 dnaH 3165189 dnaH Streptococcus thermophilus LMG 18311 DNA polymerase III subunit delta' YP_139015.1 470268 D 264199 CDS YP_139016.1 55820574 3164017 471140..471946 1 NC_006448.1 signal-petidase-like protein 471946 sip 3164017 sip Streptococcus thermophilus LMG 18311 signal-petidase-like protein YP_139016.1 471140 D 264199 CDS YP_139017.1 55820575 3164751 471933..472253 1 NC_006448.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 472253 3164751 stu0492 Streptococcus thermophilus LMG 18311 DNA replication intiation control protein YabA YP_139017.1 471933 D 264199 CDS YP_139018.1 55820576 3164372 472256..473122 1 NC_006448.1 tetrapyrrole methylase family protein 473122 3164372 stu0493 Streptococcus thermophilus LMG 18311 tetrapyrrole methylase family protein YP_139018.1 472256 D 264199 CDS YP_139019.1 55820577 3164636 473212..474495 1 NC_006448.1 ammonium transporter 474495 amtB 3164636 amtB Streptococcus thermophilus LMG 18311 ammonium transporter YP_139019.1 473212 D 264199 CDS YP_139020.1 55820578 3164293 474440..474847 1 NC_006448.1 nitrogen regulatory protein P-II 474847 gnlB 3164293 gnlB Streptococcus thermophilus LMG 18311 nitrogen regulatory protein P-II YP_139020.1 474440 D 264199 CDS YP_139021.1 55820579 3164769 474945..475601 1 NC_006448.1 peptidoglycan hydrolase 475601 mur1 3164769 mur1 Streptococcus thermophilus LMG 18311 peptidoglycan hydrolase YP_139021.1 474945 D 264199 CDS YP_139022.1 55820580 3164753 475588..476445 1 NC_006448.1 hypothetical protein 476445 3164753 stu0497 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139022.1 475588 D 264199 CDS YP_139023.1 55820581 3163961 476949..477593 1 NC_006448.1 truncated; Na/Pi cotransporter II-like protein, truncated 477593 3163961 stu0499 Streptococcus thermophilus LMG 18311 Na/Pi cotransporter II-like protein, truncated YP_139023.1 476949 D 264199 CDS YP_139024.1 55820582 3164815 477601..477747 1 NC_006448.1 truncated; Na/Pi cotransporter II-like protein, truncated 477747 3164815 stu0500 Streptococcus thermophilus LMG 18311 Na/Pi cotransporter II-like protein, truncated YP_139024.1 477601 D 264199 CDS YP_139025.1 55820583 3165201 477814..478980 1 NC_006448.1 N-acetylglucosamine-6-phosphate deacetylase 478980 nagA 3165201 nagA Streptococcus thermophilus LMG 18311 N-acetylglucosamine-6-phosphate deacetylase YP_139025.1 477814 D 264199 CDS YP_139026.1 55820584 3163747 479085..479408 1 NC_006448.1 truncated; hypothetical protein 479408 3163747 stu0502 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139026.1 479085 D 264199 CDS YP_139027.1 55820585 3164109 479281..479583 1 NC_006448.1 truncated; hypothetical protein 479583 3164109 stu0503 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139027.1 479281 D 264199 CDS YP_139028.1 55820586 3164897 479567..479935 1 NC_006448.1 truncated; hypothetical protein 479935 3164897 stu0504 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139028.1 479567 D 264199 CDS YP_139029.1 55820587 3164890 480610..481527 1 NC_006448.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 481527 glyQ 3164890 glyQ Streptococcus thermophilus LMG 18311 glycyl-tRNA synthetase subunit alpha YP_139029.1 480610 D 264199 CDS YP_139030.2 161611293 3164776 481811..483847 1 NC_006448.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 483847 glyS 3164776 glyS Streptococcus thermophilus LMG 18311 glycyl-tRNA synthetase subunit beta YP_139030.2 481811 D 264199 CDS YP_139031.1 55820589 3164803 483860..484117 1 NC_006448.1 hypothetical protein 484117 3164803 stu0508 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139031.1 483860 D 264199 CDS YP_139032.1 55820590 3164304 484279..485679 1 NC_006448.1 D-Serine/D-alanine/glycine:H+ symporter 485679 cycA 3164304 cycA Streptococcus thermophilus LMG 18311 D-Serine/D-alanine/glycine:H+ symporter YP_139032.1 484279 D 264199 CDS YP_139033.1 55820591 3165130 complement(485749..486384) 1 NC_006448.1 hypothetical protein 486384 3165130 stu0510 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139033.1 485749 R 264199 CDS YP_139034.1 55820592 3165138 486688..486864 1 NC_006448.1 truncated; beta-glucoside PTS system component IIABC, truncated 486864 3165138 stu0511 Streptococcus thermophilus LMG 18311 beta-glucoside PTS system component IIABC, truncated YP_139034.1 486688 D 264199 CDS YP_139035.1 55820593 3164782 486877..487311 1 NC_006448.1 truncated; beta-glucoside PTS system component IIABC, truncated 487311 3164782 stu0512 Streptococcus thermophilus LMG 18311 beta-glucoside PTS system component IIABC, truncated YP_139035.1 486877 D 264199 CDS YP_139036.1 55820594 3164429 487356..488072 1 NC_006448.1 truncated; beta-glucoside PTS system component IIABC, truncated 488072 3164429 stu0513 Streptococcus thermophilus LMG 18311 beta-glucoside PTS system component IIABC, truncated YP_139036.1 487356 D 264199 CDS YP_139037.1 55820595 3163881 488050..488508 1 NC_006448.1 truncated; beta-glucoside PTS system component IIABC, truncated 488508 3163881 stu0514 Streptococcus thermophilus LMG 18311 beta-glucoside PTS system component IIABC, truncated YP_139037.1 488050 D 264199 CDS YP_139038.1 55820596 3164183 complement(488630..489388) 1 NC_006448.1 peptidyl-prolyl cis-trans isomerase 489388 ppiA 3164183 ppiA Streptococcus thermophilus LMG 18311 peptidyl-prolyl cis-trans isomerase YP_139038.1 488630 R 264199 CDS YP_139039.1 55820597 3163843 489750..490040 1 NC_006448.1 hypothetical protein 490040 3163843 stu0516 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139039.1 489750 D 264199 CDS YP_139040.1 55820598 3164961 490076..490483 1 NC_006448.1 hypothetical protein 490483 3164961 stu0517 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139040.1 490076 D 264199 CDS YP_139041.1 55820599 3164540 490480..490956 1 NC_006448.1 hypothetical protein 490956 3164540 stu0518 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139041.1 490480 D 264199 CDS YP_139042.1 55820600 3164777 491102..491326 1 NC_006448.1 hypothetical protein 491326 3164777 stu0519 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139042.1 491102 D 264199 CDS YP_139043.1 55820601 3164464 491433..492347 1 NC_006448.1 LysR family transcriptional regulator 492347 3164464 stu0520 Streptococcus thermophilus LMG 18311 LysR family transcriptional regulator YP_139043.1 491433 D 264199 CDS YP_139044.1 55820602 3164814 492356..492817 1 NC_006448.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 492817 lspA 3164814 lspA Streptococcus thermophilus LMG 18311 lipoprotein signal peptidase YP_139044.1 492356 D 264199 CDS YP_139045.1 55820603 3165584 492801..493691 1 NC_006448.1 ribosomal large subunit pseudouridine synthase D 493691 rluD 3165584 rluD Streptococcus thermophilus LMG 18311 ribosomal large subunit pseudouridine synthase D YP_139045.1 492801 D 264199 CDS YP_139046.1 55820604 3165006 493836..494441 1 NC_006448.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 494441 pyrR 3165006 pyrR Streptococcus thermophilus LMG 18311 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_139046.1 493836 D 264199 CDS YP_139047.1 55820605 3164822 494755..496065 1 NC_006448.1 uracil permease 496065 pyrP 3164822 pyrP Streptococcus thermophilus LMG 18311 uracil permease YP_139047.1 494755 D 264199 CDS YP_139048.1 55820606 3164446 496090..497016 1 NC_006448.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 497016 pyrB 3164446 pyrB Streptococcus thermophilus LMG 18311 aspartate carbamoyltransferase YP_139048.1 496090 D 264199 CDS YP_139049.1 55820607 3165132 497169..498257 1 NC_006448.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 498257 carA 3165132 carA Streptococcus thermophilus LMG 18311 carbamoyl phosphate synthase small subunit YP_139049.1 497169 D 264199 CDS YP_139050.1 55820608 3164841 498602..501781 1 NC_006448.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 501781 carB 3164841 carB Streptococcus thermophilus LMG 18311 carbamoyl phosphate synthase large subunit YP_139050.1 498602 D 264199 CDS YP_139051.1 55820609 3165198 502158..502916 1 NC_006448.1 hypothetical protein 502916 3165198 stu0528 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139051.1 502158 D 264199 CDS YP_139052.1 55820610 3164831 503387..503497 1 NC_006448.1 hypothetical protein 503497 3164831 stu0529 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139052.1 503387 D 264199 CDS YP_139053.1 55820611 3164030 503635..504027 1 NC_006448.1 hypothetical protein 504027 3164030 stu0530 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139053.1 503635 D 264199 CDS YP_139054.1 55820612 3164691 504020..504124 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 504124 3164691 stu0531 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139054.1 504020 D 264199 CDS YP_139055.1 55820613 3163970 504134..504445 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 504445 3163970 stu0532 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139055.1 504134 D 264199 CDS YP_139056.1 55820614 3164843 504454..504849 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 504849 3164843 stu0533 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139056.1 504454 D 264199 CDS YP_139057.1 55820615 3164671 504846..505061 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 505061 3164671 stu0535 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139057.1 504846 D 264199 CDS YP_139058.2 161611292 3164145 505352..505855 1 NC_006448.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 505855 rplJ 3164145 rplJ Streptococcus thermophilus LMG 18311 50S ribosomal protein L10 YP_139058.2 505352 D 264199 CDS YP_139059.2 161611291 3164249 505930..506298 1 NC_006448.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 506298 rplL 3164249 rplL Streptococcus thermophilus LMG 18311 50S ribosomal protein L7/L12 YP_139059.2 505930 D 264199 CDS YP_139060.1 55820618 3163972 507552..509288 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 509288 3163972 stu0538 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_139060.1 507552 D 264199 CDS YP_139061.1 55820619 3164128 509301..511088 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 511088 3164128 stu0539 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_139061.1 509301 D 264199 CDS YP_139062.1 55820620 3164779 complement(511186..512229) 1 NC_006448.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 512229 queA 3164779 queA Streptococcus thermophilus LMG 18311 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_139062.1 511186 R 264199 CDS YP_139063.1 55820621 3163801 512304..513080 1 NC_006448.1 glucosamine-6-phosphate isomerase 513080 nagB 3163801 nagB Streptococcus thermophilus LMG 18311 glucosamine-6-phosphate isomerase YP_139063.1 512304 D 264199 CDS YP_139064.1 55820622 3164842 complement(513246..514541) 1 NC_006448.1 sensor histidine kinase 514541 hk02 3164842 hk02 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139064.1 513246 R 264199 CDS YP_139065.1 55820623 3164241 complement(514541..515266) 1 NC_006448.1 response regulator 515266 rr02 3164241 rr02 Streptococcus thermophilus LMG 18311 response regulator YP_139065.1 514541 R 264199 CDS YP_139066.1 55820624 3164864 515474..516721 1 NC_006448.1 molybdopterin biosynthesis protein (HesA/MoeB/ThiF family protein) 516721 3164864 stu0545 Streptococcus thermophilus LMG 18311 molybdopterin biosynthesis protein (HesA/MoeB/ThiF family protein) YP_139066.1 515474 D 264199 CDS YP_139067.1 55820625 3164325 516682..517629 1 NC_006448.1 ABC transporter ATP binding protein 517629 3164325 stu0546 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_139067.1 516682 D 264199 CDS YP_139068.1 55820626 3165594 517631..518353 1 NC_006448.1 ABC transporter membrane-spanning protein 518353 3165594 stu0547 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_139068.1 517631 D 264199 CDS YP_139069.1 55820627 3164383 518542..519525 1 NC_006448.1 hypothetical protein 519525 3164383 stu0548 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139069.1 518542 D 264199 CDS YP_139070.1 55820628 3164473 519683..519901 1 NC_006448.1 transcriptional repressor 519901 3164473 stu0549 Streptococcus thermophilus LMG 18311 transcriptional repressor YP_139070.1 519683 D 264199 CDS YP_139071.1 55820629 3163887 519915..520412 1 NC_006448.1 hypothetical protein 520412 3163887 stu0550 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139071.1 519915 D 264199 CDS YP_139072.1 55820630 3164406 520491..521261 1 NC_006448.1 phosphorylase Pnp/Udp family protein 521261 3164406 stu0551 Streptococcus thermophilus LMG 18311 phosphorylase Pnp/Udp family protein YP_139072.1 520491 D 264199 CDS YP_139073.1 55820631 3165012 521353..522036 1 NC_006448.1 hypothetical protein 522036 3165012 stu0552 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139073.1 521353 D 264199 CDS YP_139074.1 55820632 3164187 522116..522835 1 NC_006448.1 ribosomal small subunit pseudouridine synthase A 522835 rsuA1 3164187 rsuA1 Streptococcus thermophilus LMG 18311 ribosomal small subunit pseudouridine synthase A YP_139074.1 522116 D 264199 CDS YP_139075.1 55820633 3164243 523071..524216 1 NC_006448.1 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 524216 hipO1 3164243 hipO1 Streptococcus thermophilus LMG 18311 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_139075.1 523071 D 264199 CDS YP_139076.1 55820634 3164444 524649..524786 1 NC_006448.1 truncated; alanine dehydrogenase 524786 3164444 stu0555 Streptococcus thermophilus LMG 18311 alanine dehydrogenase YP_139076.1 524649 D 264199 CDS YP_139077.1 55820635 3165624 524761..525048 1 NC_006448.1 truncated; alanine dehydrogenase 525048 3165624 stu0556 Streptococcus thermophilus LMG 18311 alanine dehydrogenase YP_139077.1 524761 D 264199 CDS YP_139078.1 55820636 3164896 525757..527073 1 NC_006448.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 527073 3164896 stu0557 Streptococcus thermophilus LMG 18311 pyridine nucleotide-disulfide oxidoreductase YP_139078.1 525757 D 264199 CDS YP_139079.1 55820637 3164903 complement(527292..527855) 1 NC_006448.1 hypothetical protein 527855 3164903 stu0558 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139079.1 527292 R 264199 CDS YP_139080.1 55820638 3164392 528118..528996 1 NC_006448.1 mevalonate kinase 528996 mvaK1 3164392 mvaK1 Streptococcus thermophilus LMG 18311 mevalonate kinase YP_139080.1 528118 D 264199 CDS YP_139081.1 55820639 3164086 528978..529922 1 NC_006448.1 mevalonate pyrophosphate decarboxylase 529922 mvaD 3164086 mvaD Streptococcus thermophilus LMG 18311 mevalonate pyrophosphate decarboxylase YP_139081.1 528978 D 264199 CDS YP_139082.1 55820640 3165073 529915..530910 1 NC_006448.1 phosphomevalonate kinase 530910 mvaK2 3165073 mvaK2 Streptococcus thermophilus LMG 18311 phosphomevalonate kinase YP_139082.1 529915 D 264199 CDS YP_139083.1 55820641 3164672 530960..531967 1 NC_006448.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 531967 idi 3164672 idi Streptococcus thermophilus LMG 18311 isopentenyl pyrophosphate isomerase YP_139083.1 530960 D 264199 CDS YP_139084.1 55820642 3164227 532516..533898 1 NC_006448.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 533898 glmU 3164227 glmU Streptococcus thermophilus LMG 18311 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_139084.1 532516 D 264199 CDS YP_139085.1 55820643 3165144 533974..534522 1 NC_006448.1 hypothetical protein 534522 3165144 stu0564 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139085.1 533974 D 264199 CDS YP_139086.1 55820644 3164629 534526..534786 1 NC_006448.1 hypothetical protein 534786 3164629 stu0565 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139086.1 534526 D 264199 CDS YP_139087.1 55820645 3165025 534854..535546 1 NC_006448.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 535546 pfs 3165025 pfs Streptococcus thermophilus LMG 18311 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_139087.1 534854 D 264199 CDS YP_139088.1 55820646 3163776 536465..536935 1 NC_006448.1 truncated; hypothetical protein 536935 3163776 stu0567 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139088.1 536465 D 264199 CDS YP_139089.1 55820647 3164146 537066..537356 1 NC_006448.1 hypothetical protein 537356 3164146 stu0568 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139089.1 537066 D 264199 CDS YP_139090.1 55820648 3165107 537481..538485 1 NC_006448.1 glycosyl transferase family protein 538485 3165107 stu0569 Streptococcus thermophilus LMG 18311 glycosyl transferase family protein YP_139090.1 537481 D 264199 CDS YP_139091.1 55820649 3164419 538486..539808 1 NC_006448.1 glycosyl transferase family protein 539808 3164419 stu0570 Streptococcus thermophilus LMG 18311 glycosyl transferase family protein YP_139091.1 538486 D 264199 CDS YP_139092.1 55820650 3165580 540080..540367 1 NC_006448.1 hypothetical protein 540367 3165580 stu0571 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139092.1 540080 D 264199 CDS YP_139093.1 55820651 3164191 540521..542467 1 NC_006448.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 542467 thrS 3164191 thrS Streptococcus thermophilus LMG 18311 threonyl-tRNA synthetase YP_139093.1 540521 D 264199 CDS YP_139094.1 55820652 3164255 542517..543458 1 NC_006448.1 hydrolase 543458 3164255 stu0573 Streptococcus thermophilus LMG 18311 hydrolase YP_139094.1 542517 D 264199 CDS YP_139095.1 55820653 3164533 543478..544344 1 NC_006448.1 hypothetical protein 544344 3164533 stu0574 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139095.1 543478 D 264199 CDS YP_139096.1 55820654 3163955 complement(544851..545528) 1 NC_006448.1 hypothetical protein 545528 hlyIII 3163955 hlyIII Streptococcus thermophilus LMG 18311 hypothetical protein YP_139096.1 544851 R 264199 CDS YP_139097.1 55820655 3164877 complement(546146..547417) 1 NC_006448.1 3-hydroxy-3-methylglutaryl-CoA reductase 547417 mvaA 3164877 mvaA Streptococcus thermophilus LMG 18311 3-hydroxy-3-methylglutaryl-CoA reductase YP_139097.1 546146 R 264199 CDS YP_139098.1 55820656 3164875 complement(547410..548609) 1 NC_006448.1 hydroxymethylglutaryl-CoA synthase 548609 mvaS 3164875 mvaS Streptococcus thermophilus LMG 18311 hydroxymethylglutaryl-CoA synthase YP_139098.1 547410 R 264199 CDS YP_139099.1 55820657 3163764 548907..549767 1 NC_006448.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 549767 thyA 3163764 thyA Streptococcus thermophilus LMG 18311 thymidylate synthase YP_139099.1 548907 D 264199 CDS YP_139100.1 55820658 3164847 549875..550378 1 NC_006448.1 dihydrofolate reductase 550378 folA 3164847 folA Streptococcus thermophilus LMG 18311 dihydrofolate reductase YP_139100.1 549875 D 264199 CDS YP_139101.1 55820659 3164945 550383..550553 1 NC_006448.1 hypothetical protein 550553 3164945 stu0580 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139101.1 550383 D 264199 CDS YP_139102.1 55820660 3164469 550571..551797 1 NC_006448.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 551797 clpX 3164469 clpX Streptococcus thermophilus LMG 18311 ATP-dependent protease ATP-binding subunit ClpX YP_139102.1 550571 D 264199 CDS YP_139103.1 55820661 3164986 551807..552406 1 NC_006448.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 552406 engB 3164986 engB Streptococcus thermophilus LMG 18311 ribosome biogenesis GTP-binding protein YsxC YP_139103.1 551807 D 264199 CDS YP_139104.1 55820662 3164977 552461..553912 1 NC_006448.1 L-arginine permease 553912 rocE 3164977 rocE Streptococcus thermophilus LMG 18311 L-arginine permease YP_139104.1 552461 D 264199 CDS YP_139105.1 55820663 3164988 553906..554874 1 NC_006448.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 554874 mmuM 3164988 mmuM Streptococcus thermophilus LMG 18311 homocysteine methyltransferase YP_139105.1 553906 D 264199 CDS YP_139106.1 55820664 3164404 554987..555241 1 NC_006448.1 hypothetical protein 555241 3164404 stu0585 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139106.1 554987 D 264199 CDS YP_139107.1 55820665 3164374 555313..555672 1 NC_006448.1 hypothetical protein 555672 3164374 stu0586 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139107.1 555313 D 264199 CDS YP_139108.1 55820666 3163818 complement(555786..556427) 1 NC_006448.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 556427 3163818 stu0587 Streptococcus thermophilus LMG 18311 glycerol-3-phosphate acyltransferase PlsY YP_139108.1 555786 R 264199 CDS YP_139109.1 55820667 3164809 556565..558514 1 NC_006448.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 558514 parE 3164809 parE Streptococcus thermophilus LMG 18311 DNA topoisomerase IV subunit B YP_139109.1 556565 D 264199 CDS YP_139110.1 55820668 3164968 559088..561607 1 NC_006448.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 561607 parC 3164968 parC Streptococcus thermophilus LMG 18311 DNA topoisomerase IV subunit A YP_139110.1 559088 D 264199 CDS YP_139111.1 55820669 3164999 561771..562793 1 NC_006448.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 562793 bcaT 3164999 bcaT Streptococcus thermophilus LMG 18311 branched-chain amino acid aminotransferase YP_139111.1 561771 D 264199 CDS YP_139112.1 55820670 3165197 562912..563142 1 NC_006448.1 hypothetical protein 563142 3165197 stu0591 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139112.1 562912 D 264199 CDS YP_139113.2 161611290 3165205 563544..564746 1 NC_006448.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 564746 rpsA 3165205 rpsA Streptococcus thermophilus LMG 18311 30S ribosomal protein S1 YP_139113.2 563544 D 264199 CDS YP_139114.1 55820672 3164992 565574..565810 1 NC_006448.1 hypothetical protein 565810 3164992 stu0593 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139114.1 565574 D 264199 CDS YP_139115.1 55820673 3164051 565968..566195 1 NC_006448.1 hypothetical protein 566195 3164051 stu0594 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139115.1 565968 D 264199 CDS YP_139116.1 55820674 3165157 566407..566832 1 NC_006448.1 hypothetical protein 566832 3165157 stu0595 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139116.1 566407 D 264199 CDS YP_139117.1 55820675 3164560 566928..568163 1 NC_006448.1 peptidoglycan branched peptide synthesis protein 568163 murN 3164560 murN Streptococcus thermophilus LMG 18311 peptidoglycan branched peptide synthesis protein YP_139117.1 566928 D 264199 CDS YP_139118.1 55820676 3163997 568438..568596 1 NC_006448.1 truncated; oxidoreductase, truncated 568596 3163997 stu0597 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_139118.1 568438 D 264199 CDS YP_139119.1 55820677 3164356 568612..568797 1 NC_006448.1 truncated; oxidoreductase, truncated 568797 3164356 stu0598 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_139119.1 568612 D 264199 CDS YP_139120.1 55820678 3164085 568909..569223 1 NC_006448.1 truncated; oxidoreductase, truncated 569223 3164085 stu0599 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_139120.1 568909 D 264199 CDS YP_139121.1 55820679 3164979 complement(569264..569566) 1 NC_006448.1 hypothetical protein 569566 3164979 stu0600 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139121.1 569264 R 264199 CDS YP_139122.1 55820680 3164964 complement(569576..570034) 1 NC_006448.1 MutT/nudix family protein 570034 3164964 stu0601 Streptococcus thermophilus LMG 18311 MutT/nudix family protein YP_139122.1 569576 R 264199 CDS YP_139123.1 55820681 3164624 complement(570177..572435) 1 NC_006448.1 ATP-dependent Clp protease 572435 clpE 3164624 clpE Streptococcus thermophilus LMG 18311 ATP-dependent Clp protease YP_139123.1 570177 R 264199 CDS YP_139124.1 55820682 3164817 572613..573656 1 NC_006448.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 573656 argF 3164817 argF Streptococcus thermophilus LMG 18311 ornithine carbamoyltransferase YP_139124.1 572613 D 264199 CDS YP_139125.1 55820683 3163875 573725..573955 1 NC_006448.1 hypothetical protein 573955 3163875 stu0604 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139125.1 573725 D 264199 CDS YP_139126.1 55820684 3164879 574221..574904 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 574904 3164879 stu0605 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_139126.1 574221 D 264199 CDS YP_139127.1 55820685 3164985 574904..575638 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 575638 3164985 stu0606 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_139127.1 574904 D 264199 CDS YP_139128.1 55820686 3164397 575812..576288 1 NC_006448.1 ferrous iron uptake transporter protein A 576288 feoA 3164397 feoA Streptococcus thermophilus LMG 18311 ferrous iron uptake transporter protein A YP_139128.1 575812 D 264199 CDS YP_139129.1 55820687 3164927 576285..578423 1 NC_006448.1 ferrous iron transport protein B 578423 feoB 3164927 feoB Streptococcus thermophilus LMG 18311 ferrous iron transport protein B YP_139129.1 576285 D 264199 CDS YP_139130.1 55820688 3163936 578810..579034 1 NC_006448.1 hypothetical protein 579034 3163936 stu0609 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139130.1 578810 D 264199 CDS YP_139131.1 55820689 3163806 579282..579473 1 NC_006448.1 hypothetical protein 579473 3163806 stu0610 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139131.1 579282 D 264199 CDS YP_139132.1 55820690 3165051 579634..580500 1 NC_006448.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 580500 folD 3165051 folD Streptococcus thermophilus LMG 18311 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_139132.1 579634 D 264199 CDS YP_139133.1 55820691 3164225 580504..581340 1 NC_006448.1 hypothetical protein 581340 3164225 stu0612 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139133.1 580504 D 264199 CDS YP_139134.1 55820692 3164597 581462..583576 1 NC_006448.1 penicillin-binding protein 2B 583576 pbp2B 3164597 pbp2B Streptococcus thermophilus LMG 18311 penicillin-binding protein 2B YP_139134.1 581462 D 264199 CDS YP_139135.1 55820693 3163888 583686..584282 1 NC_006448.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 584282 recR 3163888 recR Streptococcus thermophilus LMG 18311 recombination protein RecR YP_139135.1 583686 D 264199 CDS YP_139136.1 55820694 3164365 584425..584796 1 NC_006448.1 truncated; BglG family transcriptional antiterminator, truncated 584796 3164365 stu0615 Streptococcus thermophilus LMG 18311 BglG family transcriptional antiterminator, truncated YP_139136.1 584425 D 264199 CDS YP_139137.1 55820695 3164767 584904..585221 1 NC_006448.1 truncated; BglG family transcriptional antiterminator, truncated 585221 3164767 stu0616 Streptococcus thermophilus LMG 18311 BglG family transcriptional antiterminator, truncated YP_139137.1 584904 D 264199 CDS YP_139138.1 55820696 3165116 585441..585938 1 NC_006448.1 metalloprotease 585938 3165116 stu0617 Streptococcus thermophilus LMG 18311 metalloprotease YP_139138.1 585441 D 264199 CDS YP_139139.1 55820697 3164995 585919..586323 1 NC_006448.1 diacylglycerol kinase 586323 dgk 3164995 dgk Streptococcus thermophilus LMG 18311 diacylglycerol kinase YP_139139.1 585919 D 264199 CDS YP_139140.1 55820698 3163897 586342..587241 1 NC_006448.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 587241 era 3163897 era Streptococcus thermophilus LMG 18311 GTP-binding protein Era YP_139140.1 586342 D 264199 CDS YP_139141.1 55820699 3164043 587288..588109 1 NC_006448.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 588109 mutM 3164043 mutM Streptococcus thermophilus LMG 18311 formamidopyrimidine-DNA glycosylase YP_139141.1 587288 D 264199 CDS YP_139142.1 55820700 3164632 588085..588699 1 NC_006448.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 588699 coaE 3164632 coaE Streptococcus thermophilus LMG 18311 dephospho-CoA kinase YP_139142.1 588085 D 264199 CDS YP_139143.1 55820701 3164518 588750..589973 1 NC_006448.1 drug:H+ antiporter-1 (DHA1) family protein 589973 pmrA 3164518 pmrA Streptococcus thermophilus LMG 18311 drug:H+ antiporter-1 (DHA1) family protein YP_139143.1 588750 D 264199 CDS YP_139144.1 55820702 3163826 589963..590109 1 NC_006448.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 590109 rpmG 3163826 rpmG Streptococcus thermophilus LMG 18311 50S ribosomal protein L33 YP_139144.1 589963 D 264199 CDS YP_139145.1 55820703 3165111 590154..590390 1 NC_006448.1 preprotein translocase subunit SecG 590390 secG 3165111 secG Streptococcus thermophilus LMG 18311 preprotein translocase subunit SecG YP_139145.1 590154 D 264199 CDS YP_139146.1 55820704 3164542 590449..592902 1 NC_006448.1 exoribonuclease R 592902 rnr 3164542 rnr Streptococcus thermophilus LMG 18311 exoribonuclease R YP_139146.1 590449 D 264199 CDS YP_139147.1 55820705 3165625 592924..593388 1 NC_006448.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 593388 smpB 3165625 smpB Streptococcus thermophilus LMG 18311 SsrA-binding protein YP_139147.1 592924 D 264199 CDS YP_139148.1 55820706 3164633 593542..594948 1 NC_006448.1 peptidyl-prolyl cis-trans isomerase 594948 pplB 3164633 pplB Streptococcus thermophilus LMG 18311 peptidyl-prolyl cis-trans isomerase YP_139148.1 593542 D 264199 CDS YP_139149.1 55820707 3164853 594950..595315 1 NC_006448.1 hypothetical protein 595315 3164853 stu0628 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139149.1 594950 D 264199 CDS YP_139150.1 55820708 3165011 complement(595418..596503) 1 NC_006448.1 dipeptidase 596503 pepQ 3165011 pepQ Streptococcus thermophilus LMG 18311 dipeptidase YP_139150.1 595418 R 264199 CDS YP_139151.1 55820709 3163861 596785..597819 1 NC_006448.1 catabolite control protein 597819 ccpA 3163861 ccpA Streptococcus thermophilus LMG 18311 catabolite control protein YP_139151.1 596785 D 264199 CDS YP_139152.1 55820710 3163812 597878..598075 1 NC_006448.1 truncated; hypothetical protein 598075 3163812 stu0631 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139152.1 597878 D 264199 CDS YP_139153.1 55820711 3164620 598181..598945 1 NC_006448.1 truncated; hypothetical protein 598945 3164620 stu0632 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139153.1 598181 D 264199 CDS YP_139154.1 55820712 3164443 598960..600075 1 NC_006448.1 glycerate kinase 600075 grk 3164443 grk Streptococcus thermophilus LMG 18311 glycerate kinase YP_139154.1 598960 D 264199 CDS YP_139155.1 55820713 3165171 complement(600114..600569) 1 NC_006448.1 hypothetical protein 600569 3165171 stu0634 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139155.1 600114 R 264199 CDS YP_139156.1 55820714 3164939 600778..602082 1 NC_006448.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 602082 eno 3164939 eno Streptococcus thermophilus LMG 18311 phosphopyruvate hydratase YP_139156.1 600778 D 264199 CDS YP_139157.1 55820715 3163973 complement(602580..604766) 1 NC_006448.1 hypothetical protein 604766 3163973 stu0636 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139157.1 602580 R 264199 CDS YP_139158.1 55820716 3164840 604928..606091 1 NC_006448.1 hypothetical protein 606091 3164840 stu0637 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139158.1 604928 D 264199 CDS YP_139159.1 55820717 3165613 606088..606765 1 NC_006448.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 606765 aroD 3165613 aroD Streptococcus thermophilus LMG 18311 3-dehydroquinate dehydratase YP_139159.1 606088 D 264199 CDS YP_139160.2 161611289 3164130 606755..607612 1 NC_006448.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 607612 aroE 3164130 aroE Streptococcus thermophilus LMG 18311 shikimate 5-dehydrogenase YP_139160.2 606755 D 264199 CDS YP_139161.1 55820719 3163908 607625..608692 1 NC_006448.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 608692 aroB 3163908 aroB Streptococcus thermophilus LMG 18311 3-dehydroquinate synthase YP_139161.1 607625 D 264199 CDS YP_139162.1 55820720 3165016 608693..609859 1 NC_006448.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 609859 aroF 3165016 aroF Streptococcus thermophilus LMG 18311 chorismate synthase YP_139162.1 608693 D 264199 CDS YP_139163.1 55820721 3164277 609889..610995 1 NC_006448.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 610995 tyrA 3164277 tyrA Streptococcus thermophilus LMG 18311 prephenate dehydrogenase YP_139163.1 609889 D 264199 CDS YP_139164.1 55820722 3163985 611005..611343 1 NC_006448.1 hypothetical protein 611343 3163985 stu0643 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139164.1 611005 D 264199 CDS YP_139165.1 55820723 3165017 611399..612349 1 NC_006448.1 L-2-hydroxyisocaproate dehydrogenase 612349 hdhL 3165017 hdhL Streptococcus thermophilus LMG 18311 L-2-hydroxyisocaproate dehydrogenase YP_139165.1 611399 D 264199 CDS YP_139166.1 55820724 3165018 612430..613713 1 NC_006448.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 613713 aroA 3165018 aroA Streptococcus thermophilus LMG 18311 3-phosphoshikimate 1-carboxyvinyltransferase YP_139166.1 612430 D 264199 CDS YP_139167.1 55820725 3165019 613706..614197 1 NC_006448.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 614197 aroK 3165019 aroK Streptococcus thermophilus LMG 18311 shikimate kinase YP_139167.1 613706 D 264199 CDS YP_139168.1 55820726 3165014 614188..615012 1 NC_006448.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 615012 pheA 3165014 pheA Streptococcus thermophilus LMG 18311 prephenate dehydratase YP_139168.1 614188 D 264199 CDS YP_139169.1 55820727 3165020 615024..616454 1 NC_006448.1 truncated; negative transcriptional regualtor-PBP synthesis, truncated 616454 3165020 stu0649 Streptococcus thermophilus LMG 18311 negative transcriptional regualtor-PBP synthesis, truncated YP_139169.1 615024 D 264199 CDS YP_139170.1 55820728 3164532 complement(616470..617411) 1 NC_006448.1 exfoliative exotoxin B 617411 eetB 3164532 eetB Streptococcus thermophilus LMG 18311 exfoliative exotoxin B YP_139170.1 616470 R 264199 CDS YP_139171.1 55820729 3164545 complement(617427..618491) 1 NC_006448.1 hypothetical protein 618491 3164545 stu0651 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139171.1 617427 R 264199 CDS YP_139172.1 55820730 3164000 complement(618531..619079) 1 NC_006448.1 macrophage infectivity potentiator--like protein 619079 mip 3164000 mip Streptococcus thermophilus LMG 18311 macrophage infectivity potentiator--like protein YP_139172.1 618531 R 264199 CDS YP_139173.1 55820731 3164074 619295..620656 1 NC_006448.1 TrmA family tRNA methyltransferase 620656 3164074 stu0653 Streptococcus thermophilus LMG 18311 TrmA family tRNA methyltransferase YP_139173.1 619295 D 264199 CDS YP_139174.1 55820732 3165045 620851..621696 1 NC_006448.1 hypothetical protein 621696 3165045 stu0654 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139174.1 620851 D 264199 CDS YP_139175.1 55820733 3165216 622082..622258 1 NC_006448.1 truncated; site-specific DNA-methyltransferase (adenine-specific) LlaI, truncated 622258 3165216 stu0655 Streptococcus thermophilus LMG 18311 site-specific DNA-methyltransferase (adenine-specific) LlaI, truncated YP_139175.1 622082 D 264199 CDS YP_139176.1 55820734 3164036 623139..623750 1 NC_006448.1 hypothetical protein 623750 3164036 stu0656 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139176.1 623139 D 264199 CDS YP_139177.1 55820735 3165000 624007..627375 1 NC_006448.1 hypothetical protein 627375 3165000 stu0657 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139177.1 624007 D 264199 CDS YP_139178.1 55820736 3165126 627553..628464 1 NC_006448.1 hypothetical protein 628464 3165126 stu0658 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139178.1 627553 D 264199 CDS YP_139179.1 55820737 3164910 628466..628789 1 NC_006448.1 hypothetical protein 628789 3164910 stu0659 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139179.1 628466 D 264199 CDS YP_139180.1 55820738 3164899 628786..629838 1 NC_006448.1 hypothetical protein 629838 3164899 stu0660 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139180.1 628786 D 264199 CDS YP_139181.1 55820739 3164067 complement(632155..632970) 1 NC_006448.1 hypothetical protein 632970 3164067 stu0661 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139181.1 632155 R 264199 CDS YP_139182.1 55820740 3164388 complement(632970..633872) 1 NC_006448.1 hypothetical protein 633872 3164388 stu0662 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139182.1 632970 R 264199 CDS YP_139183.1 55820741 3164138 634236..636368 1 NC_006448.1 transcriptional regulator 636368 tex 3164138 tex Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139183.1 634236 D 264199 CDS YP_139184.1 55820742 3165165 636355..636795 1 NC_006448.1 hypothetical protein 636795 3165165 stu0664 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139184.1 636355 D 264199 CDS YP_139185.1 55820743 3164382 636862..637125 1 NC_006448.1 hypothetical protein 637125 3164382 stu0665 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139185.1 636862 D 264199 CDS YP_139186.1 55820744 3164981 637254..638183 1 NC_006448.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 638183 ptsK 3164981 ptsK Streptococcus thermophilus LMG 18311 HPr kinase/phosphorylase YP_139186.1 637254 D 264199 CDS YP_139187.1 55820745 3164211 638183..638974 1 NC_006448.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 638974 lgt 3164211 lgt Streptococcus thermophilus LMG 18311 prolipoprotein diacylglyceryl transferase YP_139187.1 638183 D 264199 CDS YP_139188.1 55820746 3165570 639004..639495 1 NC_006448.1 hypothetical protein 639495 3165570 stu0668 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139188.1 639004 D 264199 CDS YP_139189.1 55820747 3163977 639508..639942 1 NC_006448.1 hypothetical protein 639942 3163977 stu0669 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139189.1 639508 D 264199 CDS YP_139190.1 55820748 3163915 complement(639969..640265) 1 NC_006448.1 hypothetical protein 640265 3163915 stu0670 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139190.1 639969 R 264199 CDS YP_139191.1 55820749 3164527 640498..641427 1 NC_006448.1 protease 641427 3164527 stu0671 Streptococcus thermophilus LMG 18311 protease YP_139191.1 640498 D 264199 CDS YP_139192.1 55820750 3164818 641506..642810 1 NC_006448.1 U32 family peptidase 642810 3164818 stu0672 Streptococcus thermophilus LMG 18311 U32 family peptidase YP_139192.1 641506 D 264199 CDS YP_139193.1 55820751 3164573 complement(643180..643719) 1 NC_006448.1 biotin synthase 643719 bioY1 3164573 bioY1 Streptococcus thermophilus LMG 18311 biotin synthase YP_139193.1 643180 R 264199 CDS YP_139194.1 55820752 3164929 complement(643814..644104) 1 NC_006448.1 hypothetical protein 644104 3164929 stu0675 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139194.1 643814 R 264199 CDS YP_139195.1 55820753 3165180 644224..644436 1 NC_006448.1 hypothetical protein 644436 3165180 stu0676 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139195.1 644224 D 264199 CDS YP_139196.1 55820754 3164385 complement(644473..645816) 1 NC_006448.1 metal ion (Mn2+-iron) transporter (NRAMP) family protein 645816 mntH 3164385 mntH Streptococcus thermophilus LMG 18311 metal ion (Mn2+-iron) transporter (NRAMP) family protein YP_139196.1 644473 R 264199 CDS YP_139197.1 55820755 3165181 646005..646313 1 NC_006448.1 hypothetical protein 646313 3165181 stu0678 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139197.1 646005 D 264199 CDS YP_139198.1 55820756 3164135 646332..646805 1 NC_006448.1 MutT/nudix family protein 646805 3164135 stu0679 Streptococcus thermophilus LMG 18311 MutT/nudix family protein YP_139198.1 646332 D 264199 CDS YP_139199.1 55820757 3164425 complement(646828..648900) 1 NC_006448.1 hypothetical protein 648900 3164425 stu0680 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139199.1 646828 R 264199 CDS YP_139200.1 55820758 3164861 complement(648991..649713) 1 NC_006448.1 hypothetical protein 649713 3164861 stu0681 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139200.1 648991 R 264199 CDS YP_139201.1 55820759 3163964 complement(650351..651886) 1 NC_006448.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 651886 lysS 3163964 lysS Streptococcus thermophilus LMG 18311 lysyl-tRNA synthetase YP_139201.1 650351 R 264199 CDS YP_139202.1 55820760 3164431 652144..652491 1 NC_006448.1 hypothetical protein 652491 3164431 stu0693 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139202.1 652144 D 264199 CDS YP_139203.1 55820761 3165013 652691..653245 1 NC_006448.1 hypothetical protein 653245 3165013 stu0694 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139203.1 652691 D 264199 CDS YP_139204.1 55820762 3165048 653235..653738 1 NC_006448.1 hypothetical protein 653738 3165048 stu0695 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139204.1 653235 D 264199 CDS YP_139205.1 55820763 3164676 654063..654965 1 NC_006448.1 hypothetical protein 654965 3164676 stu0696 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139205.1 654063 D 264199 CDS YP_139206.1 55820764 3165192 complement(655389..656027) 1 NC_006448.1 phosphoglycerate mutase 656027 gpmC 3165192 gpmC Streptococcus thermophilus LMG 18311 phosphoglycerate mutase YP_139206.1 655389 R 264199 CDS YP_139207.1 55820765 3165095 complement(656030..656503) 1 NC_006448.1 transcriptional regulator 656503 3165095 stu0698 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139207.1 656030 R 264199 CDS YP_139208.1 55820766 3165457 complement(656618..657565) 1 NC_006448.1 endolysin 657565 3165457 stu0699 Streptococcus thermophilus LMG 18311 endolysin YP_139208.1 656618 R 264199 CDS YP_139209.1 55820767 3165522 complement(657757..658146) 1 NC_006448.1 hypothetical protein 658146 3165522 stu0700 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139209.1 657757 R 264199 CDS YP_139210.1 55820768 3164321 complement(658402..659028) 1 NC_006448.1 hypothetical protein 659028 3164321 stu0701 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139210.1 658402 R 264199 CDS YP_139211.1 55820769 3164801 659275..659556 1 NC_006448.1 hypothetical protein 659556 3164801 stu0702 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139211.1 659275 D 264199 CDS YP_139212.1 55820770 3164982 660316..661095 1 NC_006448.1 short chain dehydrogenase/reductase family oxidoreductase 661095 3164982 stu0704 Streptococcus thermophilus LMG 18311 short chain dehydrogenase/reductase family oxidoreductase YP_139212.1 660316 D 264199 CDS YP_139213.1 55820771 3164478 661355..664345 1 NC_006448.1 type I restriction-modification system restriction subunit 664345 hsdR1 3164478 hsdR1 Streptococcus thermophilus LMG 18311 type I restriction-modification system restriction subunit YP_139213.1 661355 D 264199 CDS YP_139214.1 55820772 3165620 664335..665969 1 NC_006448.1 hypothetical protein 665969 3165620 stu0706 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139214.1 664335 D 264199 CDS YP_139215.1 55820773 3163756 665970..666869 1 NC_006448.1 hypothetical protein 666869 3163756 stu0707 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139215.1 665970 D 264199 CDS YP_139216.1 55820774 3163763 666884..668104 1 NC_006448.1 type I restriction-modification system specificty subunit 668104 hsdS1 3163763 hsdS1 Streptococcus thermophilus LMG 18311 type I restriction-modification system specificty subunit YP_139216.1 666884 D 264199 CDS YP_139217.1 55820775 3165153 668119..669987 1 NC_006448.1 hypothetical protein 669987 3165153 stu0709 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139217.1 668119 D 264199 CDS YP_139218.1 55820776 3164240 670022..670774 1 NC_006448.1 hypothetical protein 670774 3164240 stu0710 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139218.1 670022 D 264199 CDS YP_139219.1 55820777 3163782 670817..672421 1 NC_006448.1 type I restriction-modification system methyltransferase subunit 672421 hsdM1 3163782 hsdM1 Streptococcus thermophilus LMG 18311 type I restriction-modification system methyltransferase subunit YP_139219.1 670817 D 264199 CDS YP_139220.1 55820778 3163815 672628..672828 1 NC_006448.1 hypothetical protein 672828 3163815 stu0712 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139220.1 672628 D 264199 CDS YP_139221.1 55820779 3164869 673016..674020 1 NC_006448.1 deoxyribonuclease 674020 3164869 stu0713 Streptococcus thermophilus LMG 18311 deoxyribonuclease YP_139221.1 673016 D 264199 CDS YP_139222.1 55820780 3164317 674171..674731 1 NC_006448.1 cytoplasmic membrane protein 674731 lemA 3164317 lemA Streptococcus thermophilus LMG 18311 cytoplasmic membrane protein YP_139222.1 674171 D 264199 CDS YP_139223.1 55820781 3163962 674733..675632 1 NC_006448.1 metalloprotease; heat shock protein HtpX 675632 htpX 3163962 htpX Streptococcus thermophilus LMG 18311 heat shock protein HtpX YP_139223.1 674733 D 264199 CDS YP_139224.1 55820782 3165104 675750..676223 1 NC_006448.1 hypothetical protein 676223 3165104 stu0716 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139224.1 675750 D 264199 CDS YP_139225.1 55820783 3165021 676220..676615 1 NC_006448.1 hypothetical protein 676615 3165021 stu0717 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139225.1 676220 D 264199 CDS YP_139226.1 55820784 3164710 676789..679611 1 NC_006448.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 679611 ppc 3164710 ppc Streptococcus thermophilus LMG 18311 phosphoenolpyruvate carboxylase YP_139226.1 676789 D 264199 CDS YP_139227.1 55820785 3163945 679679..680713 1 NC_006448.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 680713 holA 3163945 holA Streptococcus thermophilus LMG 18311 DNA polymerase III subunit delta YP_139227.1 679679 D 264199 CDS YP_139228.1 55820786 3164641 680751..681413 1 NC_006448.1 superoxide dismutase (Mn) 681413 sodA 3164641 sodA Streptococcus thermophilus LMG 18311 superoxide dismutase (Mn) YP_139228.1 680751 D 264199 CDS YP_139229.1 55820787 3164054 681510..682889 1 NC_006448.1 hypothetical protein 682889 3164054 stu0721 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139229.1 681510 D 264199 CDS YP_139230.1 55820788 3164973 complement(682929..683576) 1 NC_006448.1 prepilin peptidase type IV 683576 pilD 3164973 pilD Streptococcus thermophilus LMG 18311 prepilin peptidase type IV YP_139230.1 682929 R 264199 CDS YP_139231.1 55820789 3164408 683685..684206 1 NC_006448.1 peroxide resistance protein,non-heme iron-containing ferritin 684206 dpr 3164408 dpr Streptococcus thermophilus LMG 18311 peroxide resistance protein,non-heme iron-containing ferritin YP_139231.1 683685 D 264199 CDS YP_139232.1 55820790 3164102 684295..684732 1 NC_006448.1 ferric transport regulator protein 684732 fur 3164102 fur Streptococcus thermophilus LMG 18311 ferric transport regulator protein YP_139232.1 684295 D 264199 CDS YP_139233.1 55820791 3164261 684946..685128 1 NC_006448.1 truncated; truncated IS1239 transposase 685128 3164261 stu0725 Streptococcus thermophilus LMG 18311 truncated IS1239 transposase YP_139233.1 684946 D 264199 CDS YP_139234.1 55820792 3164511 685138..685986 1 NC_006448.1 truncated; truncated IS1239 transposase 685986 3164511 stu0726 Streptococcus thermophilus LMG 18311 truncated IS1239 transposase YP_139234.1 685138 D 264199 CDS YP_139235.1 55820793 3164514 686087..686293 1 NC_006448.1 hypothetical protein 686293 3164514 stu0727 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139235.1 686087 D 264199 CDS YP_139236.1 55820794 3165524 686286..687254 1 NC_006448.1 glucose kinase 687254 glcK 3165524 glcK Streptococcus thermophilus LMG 18311 glucose kinase YP_139236.1 686286 D 264199 CDS YP_139237.1 55820795 3164523 687392..689239 1 NC_006448.1 GTP-binding protein TypA 689239 typA 3164523 typA Streptococcus thermophilus LMG 18311 GTP-binding protein TypA YP_139237.1 687392 D 264199 CDS YP_139238.1 55820796 3164415 689263..689535 1 NC_006448.1 hypothetical protein 689535 3164415 stu0730 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139238.1 689263 D 264199 CDS YP_139239.1 55820797 3164596 689658..691010 1 NC_006448.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 691010 murD 3164596 murD Streptococcus thermophilus LMG 18311 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_139239.1 689658 D 264199 CDS YP_139240.1 55820798 3164487 691014..692084 1 NC_006448.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 692084 murG 3164487 murG Streptococcus thermophilus LMG 18311 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_139240.1 691014 D 264199 CDS YP_139241.1 55820799 3164141 692094..693218 1 NC_006448.1 cell division protein 693218 divIB 3164141 divIB Streptococcus thermophilus LMG 18311 cell division protein YP_139241.1 692094 D 264199 CDS YP_139242.1 55820800 3164474 693342..694718 1 NC_006448.1 cell division protein 694718 ftsA 3164474 ftsA Streptococcus thermophilus LMG 18311 cell division protein YP_139242.1 693342 D 264199 CDS YP_139243.1 55820801 3165403 694747..696069 1 NC_006448.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 696069 ftsZ 3165403 ftsZ Streptococcus thermophilus LMG 18311 cell division protein FtsZ YP_139243.1 694747 D 264199 CDS YP_139244.1 55820802 3164505 696072..696755 1 NC_006448.1 hypothetical protein 696755 3164505 stu0736 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139244.1 696072 D 264199 CDS YP_139245.1 55820803 3164448 696760..697329 1 NC_006448.1 hypothetical protein 697329 3164448 stu0737 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139245.1 696760 D 264199 CDS YP_139246.1 55820804 3165240 697333..697590 1 NC_006448.1 hypothetical protein 697590 3165240 stu0738 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139246.1 697333 D 264199 CDS YP_139247.1 55820805 3165521 697590..698390 1 NC_006448.1 hypothetical protein 698390 3165521 stu0739 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139247.1 697590 D 264199 CDS YP_139248.1 55820806 3163946 698634..699509 1 NC_006448.1 cell division initiation protein 699509 divIVA 3163946 divIVA Streptococcus thermophilus LMG 18311 cell division initiation protein YP_139248.1 698634 D 264199 CDS YP_139249.1 55820807 3164426 699757..702546 1 NC_006448.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 702546 ileS 3164426 ileS Streptococcus thermophilus LMG 18311 isoleucyl-tRNA synthetase YP_139249.1 699757 D 264199 CDS YP_139250.1 55820808 3164665 complement(702931..703167) 1 NC_006448.1 truncated; truncated IS1193 transposase 703167 3164665 stu0743 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139250.1 702931 R 264199 CDS YP_139251.1 55820809 3164666 703761..704972 1 NC_006448.1 hypothetical protein 704972 3164666 stu0745 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139251.1 703761 D 264199 CDS YP_139252.2 161611288 3164004 complement(705146..705388) 1 NC_006448.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 705388 rpmE2 3164004 rpmE2 Streptococcus thermophilus LMG 18311 50S ribosomal protein L31 YP_139252.2 705146 R 264199 CDS YP_139253.1 55820811 3164667 complement(705494..706432) 1 NC_006448.1 thiamine biosynthesis lipoprotein 706432 apbE 3164667 apbE Streptococcus thermophilus LMG 18311 thiamine biosynthesis lipoprotein YP_139253.1 705494 R 264199 CDS YP_139254.1 55820812 3163820 complement(706413..707357) 1 NC_006448.1 hypothetical protein 707357 3163820 stu0748 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139254.1 706413 R 264199 CDS YP_139255.1 55820813 3164594 complement(707438..708256) 1 NC_006448.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 708256 3164594 stu0749 Streptococcus thermophilus LMG 18311 glutathione S-transferase YghU YP_139255.1 707438 R 264199 CDS YP_139256.1 55820814 3163947 708396..709406 1 NC_006448.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 709406 add 3163947 add Streptococcus thermophilus LMG 18311 adenosine deaminase YP_139256.1 708396 D 264199 CDS YP_139257.1 55820815 3163949 709635..710231 1 NC_006448.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 710231 tdk 3163949 tdk Streptococcus thermophilus LMG 18311 thymidine kinase YP_139257.1 709635 D 264199 CDS YP_139258.1 55820816 3163951 710268..711347 1 NC_006448.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 711347 prfA 3163951 prfA Streptococcus thermophilus LMG 18311 peptide chain release factor 1 YP_139258.1 710268 D 264199 CDS YP_139259.1 55820817 3163952 711344..712177 1 NC_006448.1 protoporphyrinogen oxidase 712177 hemK 3163952 hemK Streptococcus thermophilus LMG 18311 protoporphyrinogen oxidase YP_139259.1 711344 D 264199 CDS YP_139260.1 55820818 3165187 712164..712769 1 NC_006448.1 Sua5/YciO/YrdC family protein 712769 3165187 stu0754 Streptococcus thermophilus LMG 18311 Sua5/YciO/YrdC family protein YP_139260.1 712164 D 264199 CDS YP_139261.1 55820819 3165188 712864..714114 1 NC_006448.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 714114 glyA 3165188 glyA Streptococcus thermophilus LMG 18311 serine hydroxymethyltransferase YP_139261.1 712864 D 264199 CDS YP_139262.1 55820820 3164472 714121..715098 1 NC_006448.1 hypothetical protein 715098 3164472 stu0756 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139262.1 714121 D 264199 CDS YP_139263.1 55820821 3165191 715046..715711 1 NC_006448.1 hypothetical protein 715711 3165191 stu0757 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139263.1 715046 D 264199 CDS YP_139264.1 55820822 3164709 715744..717483 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 717483 3164709 stu0758 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_139264.1 715744 D 264199 CDS YP_139265.1 55820823 3165509 717350..719221 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 719221 3165509 stu0759 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_139265.1 717350 D 264199 CDS YP_139266.1 55820824 3164714 719263..719529 1 NC_006448.1 component involved in D-alanylation of teichoic acids 719529 dltX 3164714 dltX Streptococcus thermophilus LMG 18311 component involved in D-alanylation of teichoic acids YP_139266.1 719263 D 264199 CDS YP_139267.1 55820825 3165168 719538..721088 1 NC_006448.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 721088 dltA 3165168 dltA Streptococcus thermophilus LMG 18311 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_139267.1 719538 D 264199 CDS YP_139268.1 55820826 3164715 721085..722332 1 NC_006448.1 hypothetical protein 722332 dltB 3164715 dltB Streptococcus thermophilus LMG 18311 hypothetical protein YP_139268.1 721085 D 264199 CDS YP_139269.1 55820827 3165458 722350..722589 1 NC_006448.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 722589 dltC 3165458 dltC Streptococcus thermophilus LMG 18311 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_139269.1 722350 D 264199 CDS YP_139270.1 55820828 3165141 722582..723850 1 NC_006448.1 hypothetical protein 723850 dltD 3165141 dltD Streptococcus thermophilus LMG 18311 hypothetical protein YP_139270.1 722582 D 264199 CDS YP_139271.1 55820829 3164891 complement(723903..724121) 1 NC_006448.1 truncated; hypothetical protein 724121 3164891 stu0765 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139271.1 723903 R 264199 CDS YP_139272.1 55820830 3164955 complement(724185..724391) 1 NC_006448.1 truncated; hypothetical protein 724391 3164955 stu0766 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139272.1 724185 R 264199 CDS YP_139273.1 55820831 3164892 complement(724405..724740) 1 NC_006448.1 truncated; hypothetical protein 724740 3164892 stu0767 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139273.1 724405 R 264199 CDS YP_139274.1 55820832 3164563 complement(724799..724981) 1 NC_006448.1 truncated; hypothetical protein 724981 3164563 stu0768 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139274.1 724799 R 264199 CDS YP_139275.1 55820833 3164893 complement(724974..725252) 1 NC_006448.1 truncated; hypothetical protein 725252 3164893 stu0769 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139275.1 724974 R 264199 CDS YP_139276.1 55820834 3165428 complement(725450..728086) 1 NC_006448.1 Ca2+, Mn2+-P-type ATPase 728086 pacL1 3165428 pacL1 Streptococcus thermophilus LMG 18311 Ca2+, Mn2+-P-type ATPase YP_139276.1 725450 R 264199 CDS YP_139277.1 55820835 3163740 complement(728263..729981) 1 NC_006448.1 para-aminobenzoate synthetase component I 729981 pabB 3163740 pabB Streptococcus thermophilus LMG 18311 para-aminobenzoate synthetase component I YP_139277.1 728263 R 264199 CDS YP_139278.1 55820836 3164829 730128..730463 1 NC_006448.1 phage protein 730463 3164829 stu0784 Streptococcus thermophilus LMG 18311 phage protein YP_139278.1 730128 D 264199 CDS YP_139279.1 55820837 3164830 730752..733040 1 NC_006448.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 733040 metE 3164830 metE Streptococcus thermophilus LMG 18311 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_139279.1 730752 D 264199 CDS YP_139280.1 55820838 3164552 733169..734104 1 NC_006448.1 5,10-methylenetetrahydrofolate reductase 734104 metF 3164552 metF Streptococcus thermophilus LMG 18311 5,10-methylenetetrahydrofolate reductase YP_139280.1 733169 D 264199 CDS YP_139281.1 55820839 3164602 complement(734244..735962) 1 NC_006448.1 phosphoglucomutase 735962 pgmA 3164602 pgmA Streptococcus thermophilus LMG 18311 phosphoglucomutase YP_139281.1 734244 R 264199 CDS YP_139282.1 55820840 3164603 complement(736045..736620) 1 NC_006448.1 hypothetical protein 736620 3164603 stu0788 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139282.1 736045 R 264199 CDS YP_139283.1 55820841 3164604 complement(736645..737220) 1 NC_006448.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 737220 dfp1 3164604 dfp1 Streptococcus thermophilus LMG 18311 phosphopantothenoylcysteine decarboxylase YP_139283.1 736645 R 264199 CDS YP_139284.1 55820842 3164605 complement(737183..737866) 1 NC_006448.1 phosphopantothenate--cysteine ligase 737866 dfp2 3164605 dfp2 Streptococcus thermophilus LMG 18311 phosphopantothenate--cysteine ligase YP_139284.1 737183 R 264199 CDS YP_139285.1 55820843 3164606 738060..739730 1 NC_006448.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 739730 fhs 3164606 fhs Streptococcus thermophilus LMG 18311 formate--tetrahydrofolate ligase YP_139285.1 738060 D 264199 CDS YP_139286.1 55820844 3164303 740054..740452 1 NC_006448.1 truncated; response regulator, truncated 740452 3164303 stu0792 Streptococcus thermophilus LMG 18311 response regulator, truncated YP_139286.1 740054 D 264199 CDS YP_139287.1 55820845 3165554 740580..740879 1 NC_006448.1 truncated; sensor histidine kinase, truncated 740879 3165554 stu0793 Streptococcus thermophilus LMG 18311 sensor histidine kinase, truncated YP_139287.1 740580 D 264199 CDS YP_139288.1 55820846 3165179 740957..741280 1 NC_006448.1 truncated; sensor histidine kinase, truncated 741280 3165179 stu0794 Streptococcus thermophilus LMG 18311 sensor histidine kinase, truncated YP_139288.1 740957 D 264199 CDS YP_139289.1 55820847 3164550 741282..741998 1 NC_006448.1 truncated; sensor histidine kinase, truncated 741998 3164550 stu0795 Streptococcus thermophilus LMG 18311 sensor histidine kinase, truncated YP_139289.1 741282 D 264199 CDS YP_139290.1 55820848 3165089 complement(742068..742937) 1 NC_006448.1 IS3 familytransposase orf2 742937 tnpSth1 3165089 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf2 YP_139290.1 742068 R 264199 CDS YP_139291.1 55820849 3165203 complement(742952..743692) 1 NC_006448.1 IS3 familytransposase orf1 743692 tnpSth1 3165203 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf1 YP_139291.1 742952 R 264199 CDS YP_139292.2 161611287 3165183 complement(743774..744010) 1 NC_006448.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 744010 rpsT 3165183 rpsT Streptococcus thermophilus LMG 18311 30S ribosomal protein S20 YP_139292.2 743774 R 264199 CDS YP_139293.1 55820851 3165184 complement(744079..744999) 1 NC_006448.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 744999 coaA 3165184 coaA Streptococcus thermophilus LMG 18311 pantothenate kinase YP_139293.1 744079 R 264199 CDS YP_139294.1 55820852 3165381 745272..745913 1 NC_006448.1 hypothetical protein 745913 3165381 stu0800 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139294.1 745272 D 264199 CDS YP_139295.1 55820853 3165043 745929..746111 1 NC_006448.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 746111 3165043 stu0801 Streptococcus thermophilus LMG 18311 pyrimidine-nucleoside phosphorylase, truncated YP_139295.1 745929 D 264199 CDS YP_139296.1 55820854 3163939 746193..746363 1 NC_006448.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 746363 3163939 stu0802 Streptococcus thermophilus LMG 18311 pyrimidine-nucleoside phosphorylase, truncated YP_139296.1 746193 D 264199 CDS YP_139297.1 55820855 3163941 746344..746730 1 NC_006448.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 746730 3163941 stu0803 Streptococcus thermophilus LMG 18311 pyrimidine-nucleoside phosphorylase, truncated YP_139297.1 746344 D 264199 CDS YP_139298.1 55820856 3165479 746748..747143 1 NC_006448.1 truncated; pyrimidine-nucleoside phosphorylase, truncated 747143 3165479 stu0804 Streptococcus thermophilus LMG 18311 pyrimidine-nucleoside phosphorylase, truncated YP_139298.1 746748 D 264199 CDS YP_139299.1 55820857 3165548 747483..747878 1 NC_006448.1 truncated; deoxyribose-phosphate aldolase, truncated 747878 3165548 stu0806 Streptococcus thermophilus LMG 18311 deoxyribose-phosphate aldolase, truncated YP_139299.1 747483 D 264199 CDS YP_139300.1 55820858 3165534 747853..748197 1 NC_006448.1 cytidine deaminase 748197 cdd 3165534 cdd Streptococcus thermophilus LMG 18311 cytidine deaminase YP_139300.1 747853 D 264199 CDS YP_139301.1 55820859 3163943 748269..749396 1 NC_006448.1 hypothetical protein 749396 3163943 stu0808 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139301.1 748269 D 264199 CDS YP_139302.1 55820860 3163944 749495..751048 1 NC_006448.1 carbohydrate ABC uptake transporter ATP-binding protein 751048 3163944 stu0809 Streptococcus thermophilus LMG 18311 carbohydrate ABC uptake transporter ATP-binding protein YP_139302.1 749495 D 264199 CDS YP_139303.1 55820861 3164340 751041..752108 1 NC_006448.1 carbohydrate ABC uptake transporter membrane-spanning protein 752108 3164340 stu0810 Streptococcus thermophilus LMG 18311 carbohydrate ABC uptake transporter membrane-spanning protein YP_139303.1 751041 D 264199 CDS YP_139304.1 55820862 3163963 752110..753066 1 NC_006448.1 carbohydrate ABC uptake transporter membrane-spanning protein 753066 3163963 stu0811 Streptococcus thermophilus LMG 18311 carbohydrate ABC uptake transporter membrane-spanning protein YP_139304.1 752110 D 264199 CDS YP_139305.1 55820863 3165120 complement(753170..753805) 1 NC_006448.1 hypothetical protein 753805 3165120 stu0812 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139305.1 753170 R 264199 CDS YP_139306.1 55820864 3163966 753868..755541 1 NC_006448.1 unwinds DNA; ATP-dependent DNA helicase 755541 3163966 stu0813 Streptococcus thermophilus LMG 18311 ATP-dependent DNA helicase YP_139306.1 753868 D 264199 CDS YP_139307.1 55820865 3164055 755605..756387 1 NC_006448.1 truncated; ATP-dependent DNA helicase, truncated 756387 3164055 stu0814 Streptococcus thermophilus LMG 18311 ATP-dependent DNA helicase, truncated YP_139307.1 755605 D 264199 CDS YP_139308.1 55820866 3164600 756583..757014 1 NC_006448.1 hypothetical protein 757014 3164600 stu0815 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139308.1 756583 D 264199 CDS YP_139309.1 55820867 3164601 757019..758200 1 NC_006448.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 758200 aspC1 3164601 aspC1 Streptococcus thermophilus LMG 18311 aspartate aminotransferase YP_139309.1 757019 D 264199 CDS YP_139310.1 55820868 3163778 758237..759583 1 NC_006448.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 759583 asnC 3163778 asnC Streptococcus thermophilus LMG 18311 asparaginyl-tRNA synthetase YP_139310.1 758237 D 264199 CDS YP_139311.1 55820869 3164413 759610..760017 1 NC_006448.1 hypothetical protein 760017 3164413 stu0819 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139311.1 759610 D 264199 CDS YP_139312.1 55820870 3164548 complement(760245..760463) 1 NC_006448.1 truncated; truncated IS1193 transposase 760463 3164548 stu0821 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139312.1 760245 R 264199 CDS YP_139313.1 55820871 3163780 complement(760551..760757) 1 NC_006448.1 truncated; truncated IS1193 transposase 760757 3163780 stu0822 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139313.1 760551 R 264199 CDS YP_139314.1 55820872 3164922 complement(760754..760891) 1 NC_006448.1 truncated; truncated IS1193 transposase 760891 3164922 stu0823 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139314.1 760754 R 264199 CDS YP_139315.1 55820873 3164924 761099..761479 1 NC_006448.1 translation initiation inhibitor 761479 3164924 stu0824 Streptococcus thermophilus LMG 18311 translation initiation inhibitor YP_139315.1 761099 D 264199 CDS YP_139316.1 55820874 3164923 761653..762306 1 NC_006448.1 hypothetical protein 762306 3164923 stu0825 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139316.1 761653 D 264199 CDS YP_139317.1 55820875 3164925 762306..762749 1 NC_006448.1 6-pyruvoyl tetrahydrobiopterin synthase 762749 ptpS 3164925 ptpS Streptococcus thermophilus LMG 18311 6-pyruvoyl tetrahydrobiopterin synthase YP_139317.1 762306 D 264199 CDS YP_139318.1 55820876 3164937 762742..763458 1 NC_006448.1 coenzyme PQQ synthesis protein 763458 3164937 stu0827 Streptococcus thermophilus LMG 18311 coenzyme PQQ synthesis protein YP_139318.1 762742 D 264199 CDS YP_139319.1 55820877 3164906 763533..764069 1 NC_006448.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 764069 3164906 stu0828 Streptococcus thermophilus LMG 18311 7-cyano-7-deazaguanine reductase YP_139319.1 763533 D 264199 CDS YP_139320.1 55820878 3164908 764889..765077 1 NC_006448.1 hypothetical protein 765077 3164908 stu0829 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139320.1 764889 D 264199 CDS YP_139321.1 55820879 3164642 765282..766052 1 NC_006448.1 hypothetical protein 766052 3164642 stu0830 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139321.1 765282 D 264199 CDS YP_139322.1 55820880 3164643 766033..766923 1 NC_006448.1 hypothetical protein 766923 3164643 stu0831 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139322.1 766033 D 264199 CDS YP_139323.1 55820881 3164644 766920..767894 1 NC_006448.1 hypothetical protein 767894 3164644 stu0832 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139323.1 766920 D 264199 CDS YP_139324.1 55820882 3164645 767891..768802 1 NC_006448.1 hypothetical protein 768802 3164645 stu0833 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139324.1 767891 D 264199 CDS YP_139325.1 55820883 3164646 769091..769570 1 NC_006448.1 truncated; dipeptidase, truncated 769570 3164646 stu0835 Streptococcus thermophilus LMG 18311 dipeptidase, truncated YP_139325.1 769091 D 264199 CDS YP_139326.1 55820884 3164647 769577..769813 1 NC_006448.1 truncated; dipeptidase, truncated 769813 3164647 stu0836 Streptococcus thermophilus LMG 18311 dipeptidase, truncated YP_139326.1 769577 D 264199 CDS YP_139327.1 55820885 3164660 770104..770313 1 NC_006448.1 cold shock protein A 770313 cspA 3164660 cspA Streptococcus thermophilus LMG 18311 cold shock protein A YP_139327.1 770104 D 264199 CDS YP_139328.1 55820886 3165368 770527..770793 1 NC_006448.1 cold shock protein B 770793 cspB 3165368 cspB Streptococcus thermophilus LMG 18311 cold shock protein B YP_139328.1 770527 D 264199 CDS YP_139329.1 55820887 3164661 771091..772299 1 NC_006448.1 IS1191 transposase 772299 tnp1191 3164661 tnp1191 Streptococcus thermophilus LMG 18311 IS1191 transposase YP_139329.1 771091 D 264199 CDS YP_139330.1 55820888 3164662 complement(772420..774627) 1 NC_006448.1 Cu2+-Cu+-Ag+-P-type ATPase 774627 copB 3164662 copB Streptococcus thermophilus LMG 18311 Cu2+-Cu+-Ag+-P-type ATPase YP_139330.1 772420 R 264199 CDS YP_139331.1 55820889 3164663 complement(774818..775009) 1 NC_006448.1 truncated; truncated IS1191 transposase 775009 3164663 stu0841 Streptococcus thermophilus LMG 18311 truncated IS1191 transposase YP_139331.1 774818 R 264199 CDS YP_139332.1 55820890 3164142 complement(775051..775614) 1 NC_006448.1 truncated; truncated IS1191 transposase 775614 3164142 stu0842 Streptococcus thermophilus LMG 18311 truncated IS1191 transposase YP_139332.1 775051 R 264199 CDS YP_139333.1 55820891 3164755 complement(775647..776006) 1 NC_006448.1 truncated; truncated IS1191 transposase 776006 3164755 stu0843 Streptococcus thermophilus LMG 18311 truncated IS1191 transposase YP_139333.1 775647 R 264199 CDS YP_139334.1 55820892 3163934 complement(776053..777078) 1 NC_006448.1 truncated; type I restriction-modification system restriction subunit, truncated 777078 3163934 stu0844 Streptococcus thermophilus LMG 18311 type I restriction-modification system restriction subunit, truncated YP_139334.1 776053 R 264199 CDS YP_139335.1 55820893 3164529 777824..778735 1 NC_006448.1 cysteine synthase 778735 cysM2 3164529 cysM2 Streptococcus thermophilus LMG 18311 cysteine synthase YP_139335.1 777824 D 264199 CDS YP_139336.1 55820894 3165105 778757..779941 1 NC_006448.1 cystathionine beta-lyase 779941 metB2 3165105 metB2 Streptococcus thermophilus LMG 18311 cystathionine beta-lyase YP_139336.1 778757 D 264199 CDS YP_139337.1 55820895 3164731 779883..780464 1 NC_006448.1 serine acetyltransferase 780464 cysE2 3164731 cysE2 Streptococcus thermophilus LMG 18311 serine acetyltransferase YP_139337.1 779883 D 264199 CDS YP_139338.1 55820896 3163830 780961..782169 1 NC_006448.1 IS1191 transposase 782169 tnp1191 3163830 tnp1191 Streptococcus thermophilus LMG 18311 IS1191 transposase YP_139338.1 780961 D 264199 CDS YP_139339.1 55820897 3165087 complement(782426..782572) 1 NC_006448.1 truncated; type I restriction-modification system specificty subunit, truncated 782572 3165087 stu0850 Streptococcus thermophilus LMG 18311 type I restriction-modification system specificty subunit, truncated YP_139339.1 782426 R 264199 CDS YP_139340.1 55820898 3163823 complement(782642..782968) 1 NC_006448.1 truncated; type I restriction-modification system specificty subunit, truncated 782968 3163823 stu0851 Streptococcus thermophilus LMG 18311 type I restriction-modification system specificty subunit, truncated YP_139340.1 782642 R 264199 CDS YP_139341.1 55820899 3165311 complement(782965..783597) 1 NC_006448.1 truncated; type I restriction-modification system methyltransferase subunit, truncated 783597 3165311 stu0852 Streptococcus thermophilus LMG 18311 type I restriction-modification system methyltransferase subunit, truncated YP_139341.1 782965 R 264199 CDS YP_139342.1 55820900 3165023 784076..784963 1 NC_006448.1 glucose/ribose porter (GRP) family protein 784963 3165023 stu0855 Streptococcus thermophilus LMG 18311 glucose/ribose porter (GRP) family protein YP_139342.1 784076 D 264199 CDS YP_139343.1 55820901 3165370 785579..785773 1 NC_006448.1 truncated; type I restriction-modification system restriction subunit, truncated 785773 3165370 stu0856 Streptococcus thermophilus LMG 18311 type I restriction-modification system restriction subunit, truncated YP_139343.1 785579 D 264199 CDS YP_139344.1 55820902 3163922 785953..786285 1 NC_006448.1 truncated; type I restriction-modification system methyltransferase subunit, truncated 786285 3163922 stu0857 Streptococcus thermophilus LMG 18311 type I restriction-modification system methyltransferase subunit, truncated YP_139344.1 785953 D 264199 CDS YP_139345.1 55820903 3164068 complement(786573..787238) 1 NC_006448.1 hypothetical protein 787238 3164068 stu0859 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139345.1 786573 R 264199 CDS YP_139346.1 55820904 3163925 787447..788991 1 NC_006448.1 zinc (Zn2+) ABC uptake transporter substrate binding protein 788991 adcA 3163925 adcA Streptococcus thermophilus LMG 18311 zinc (Zn2+) ABC uptake transporter substrate binding protein YP_139346.1 787447 D 264199 CDS YP_139347.1 55820905 3165492 789209..789607 1 NC_006448.1 hypothetical protein 789607 3165492 stu0861 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139347.1 789209 D 264199 CDS YP_139348.1 55820906 3165027 complement(790120..790419) 1 NC_006448.1 truncated; hypothetical protein 790419 3165027 stu0863 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139348.1 790120 R 264199 CDS YP_139349.1 55820907 3164572 complement(790359..790838) 1 NC_006448.1 truncated; hypothetical protein 790838 3164572 stu0864 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139349.1 790359 R 264199 CDS YP_139350.1 55820908 3165028 complement(790813..791118) 1 NC_006448.1 truncated; hypothetical protein 791118 3165028 stu0865 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139350.1 790813 R 264199 CDS YP_139351.1 55820909 3164367 complement(791093..791221) 1 NC_006448.1 truncated; hypothetical protein 791221 3164367 stu0866 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139351.1 791093 R 264199 CDS YP_139352.1 55820910 3164292 complement(791539..792546) 1 NC_006448.1 hypothetical protein 792546 3164292 stu0868 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139352.1 791539 R 264199 CDS YP_139353.1 55820911 3165207 792954..793433 1 NC_006448.1 peptidoglycan hydrolase 793433 mur2 3165207 mur2 Streptococcus thermophilus LMG 18311 peptidoglycan hydrolase YP_139353.1 792954 D 264199 CDS YP_139354.1 55820912 3164228 793445..793663 1 NC_006448.1 truncated; hypothetical protein 793663 3164228 stu0870 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139354.1 793445 D 264199 CDS YP_139355.1 55820913 3164057 793667..794221 1 NC_006448.1 truncated; hypothetical protein 794221 3164057 stu0871 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139355.1 793667 D 264199 CDS YP_139356.1 55820914 3164056 complement(794419..795327) 1 NC_006448.1 metCcysK operon transcriptional activator 795327 cmhR 3164056 cmhR Streptococcus thermophilus LMG 18311 metCcysK operon transcriptional activator YP_139356.1 794419 R 264199 CDS YP_139357.1 55820915 3164154 795534..797342 1 NC_006448.1 isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 797342 glmS 3164154 glmS Streptococcus thermophilus LMG 18311 glucosamine--fructose-6-phosphate aminotransferase YP_139357.1 795534 D 264199 CDS YP_139358.1 55820916 3163996 797460..797789 1 NC_006448.1 PhnA-like protein 797789 phnA 3163996 phnA Streptococcus thermophilus LMG 18311 PhnA-like protein YP_139358.1 797460 D 264199 CDS YP_139359.1 55820917 3163954 797983..798624 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 798624 3163954 stu0875 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_139359.1 797983 D 264199 CDS YP_139360.1 55820918 3164541 798633..799262 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 799262 3164541 stu0876 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_139360.1 798633 D 264199 CDS YP_139361.1 55820919 3164197 799275..800126 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 800126 3164197 stu0877 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139361.1 799275 D 264199 CDS YP_139362.1 55820920 3164427 800589..801410 1 NC_006448.1 truncated; SOS responce UmuC protein, truncated 801410 3164427 stu0879 Streptococcus thermophilus LMG 18311 SOS responce UmuC protein, truncated YP_139362.1 800589 D 264199 CDS YP_139363.1 55820921 3164618 802182..802535 1 NC_006448.1 truncated; alcohol dehydrogenase 802535 3164618 stu0880 Streptococcus thermophilus LMG 18311 alcohol dehydrogenase YP_139363.1 802182 D 264199 CDS YP_139364.1 55820922 3164428 802549..802680 1 NC_006448.1 truncated; alcohol dehydrogenase 802680 3164428 stu0881 Streptococcus thermophilus LMG 18311 alcohol dehydrogenase YP_139364.1 802549 D 264199 CDS YP_139365.1 55820923 3164430 802726..803214 1 NC_006448.1 truncated; alcohol dehydrogenase 803214 3164430 stu0882 Streptococcus thermophilus LMG 18311 alcohol dehydrogenase YP_139365.1 802726 D 264199 CDS YP_139366.1 55820924 3164433 complement(803838..806624) 1 NC_006448.1 DNA endonuclease, type III restriction and modification system 806624 sthIR 3164433 sthIR Streptococcus thermophilus LMG 18311 DNA endonuclease, type III restriction and modification system YP_139366.1 803838 R 264199 CDS YP_139367.1 55820925 3164434 complement(806626..808551) 1 NC_006448.1 type III restriction-modification system methylation subunit 808551 sthIM 3164434 sthIM Streptococcus thermophilus LMG 18311 type III restriction-modification system methylation subunit YP_139367.1 806626 R 264199 CDS YP_139368.1 55820926 3164528 complement(808774..810357) 1 NC_006448.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 810357 guaA 3164528 guaA Streptococcus thermophilus LMG 18311 GMP synthase YP_139368.1 808774 R 264199 CDS YP_139369.1 55820927 3164188 810505..811203 1 NC_006448.1 GntR family transcriptional regulator 811203 3164188 stu0887 Streptococcus thermophilus LMG 18311 GntR family transcriptional regulator YP_139369.1 810505 D 264199 CDS YP_139370.1 55820928 3164009 811270..811602 1 NC_006448.1 DNA-binding protein 811602 3164009 stu0888 Streptococcus thermophilus LMG 18311 DNA-binding protein YP_139370.1 811270 D 264199 CDS YP_139371.1 55820929 3164190 811635..813197 1 NC_006448.1 signal recognition particle 813197 ffh 3164190 ffh Streptococcus thermophilus LMG 18311 signal recognition particle YP_139371.1 811635 D 264199 CDS YP_139372.1 55820930 3164192 813239..813826 1 NC_006448.1 hypothetical protein 813826 3164192 stu0890 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139372.1 813239 D 264199 CDS YP_139373.1 55820931 3165340 813850..814365 1 NC_006448.1 biotin repressor family transcriptional regulator 814365 3165340 stu0891 Streptococcus thermophilus LMG 18311 biotin repressor family transcriptional regulator YP_139373.1 813850 D 264199 CDS YP_139374.1 55820932 3164195 814460..815149 1 NC_006448.1 transcriptional regulator 815149 3164195 stu0892 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139374.1 814460 D 264199 CDS YP_139375.1 55820933 3164832 815277..816131 1 NC_006448.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 816131 rbgA 3164832 rbgA Streptococcus thermophilus LMG 18311 ribosomal biogenesis GTPase YP_139375.1 815277 D 264199 CDS YP_139376.1 55820934 3164833 816103..816885 1 NC_006448.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 816885 rnhB 3164833 rnhB Streptococcus thermophilus LMG 18311 ribonuclease HII YP_139376.1 816103 D 264199 CDS YP_139377.1 55820935 3164835 816896..817816 1 NC_006448.1 transcriptional regulator 817816 3164835 stu0895 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139377.1 816896 D 264199 CDS YP_139378.1 55820936 3164834 817884..818723 1 NC_006448.1 Smf family DNA processing protein 818723 dprA 3164834 dprA Streptococcus thermophilus LMG 18311 Smf family DNA processing protein YP_139378.1 817884 D 264199 CDS YP_139379.1 55820937 3165030 818891..821035 1 NC_006448.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 821035 topA 3165030 topA Streptococcus thermophilus LMG 18311 DNA topoisomerase I YP_139379.1 818891 D 264199 CDS YP_139380.1 55820938 3164837 complement(821099..821968) 1 NC_006448.1 IS3 familytransposase orf2 821968 tnpSth1 3164837 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf2 YP_139380.1 821099 R 264199 CDS YP_139381.1 55820939 3165024 complement(821983..822723) 1 NC_006448.1 IS3 familytransposase orf1 822723 tnpSth1 3165024 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf1 YP_139381.1 821983 R 264199 CDS YP_139382.1 55820940 3165473 822839..823663 1 NC_006448.1 hypothetical protein 823663 3165473 stu0900 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139382.1 822839 D 264199 CDS YP_139383.1 55820941 3164655 823699..824358 1 NC_006448.1 response regulator 824358 rr04 3164655 rr04 Streptococcus thermophilus LMG 18311 response regulator YP_139383.1 823699 D 264199 CDS YP_139384.1 55820942 3165611 824331..825743 1 NC_006448.1 sensor histidine kinase 825743 hk04 3165611 hk04 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139384.1 824331 D 264199 CDS YP_139385.1 55820943 3164280 825844..827187 1 NC_006448.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 827187 gid 3164280 gid Streptococcus thermophilus LMG 18311 tRNA (uracil-5-)-methyltransferase Gid YP_139385.1 825844 D 264199 CDS YP_139386.1 55820944 3165616 complement(827190..827414) 1 NC_006448.1 truncated; hypothetical protein 827414 3165616 stu0904 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139386.1 827190 R 264199 CDS YP_139387.1 55820945 3164223 complement(827451..828242) 1 NC_006448.1 truncated; hypothetical protein 828242 3164223 stu0905 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139387.1 827451 R 264199 CDS YP_139388.1 55820946 3164804 828553..828981 1 NC_006448.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 828981 ndk 3164804 ndk Streptococcus thermophilus LMG 18311 nucleoside diphosphate kinase YP_139388.1 828553 D 264199 CDS YP_139389.1 55820947 3164099 828971..829276 1 NC_006448.1 hypothetical protein 829276 3164099 stu0907 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139389.1 828971 D 264199 CDS YP_139390.1 55820948 3164759 829457..829828 1 NC_006448.1 truncated; acetoin reductase, truncated 829828 3164759 stu0909 Streptococcus thermophilus LMG 18311 acetoin reductase, truncated YP_139390.1 829457 D 264199 CDS YP_139391.1 55820949 3165114 830104..830250 1 NC_006448.1 truncated; acetoin reductase, truncated 830250 3165114 stu0910 Streptococcus thermophilus LMG 18311 acetoin reductase, truncated YP_139391.1 830104 D 264199 CDS YP_139392.1 55820950 3165068 830638..832470 1 NC_006448.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 832470 lepA 3165068 lepA Streptococcus thermophilus LMG 18311 GTP-binding protein LepA YP_139392.1 830638 D 264199 CDS YP_139393.1 55820951 3164989 832876..833217 1 NC_006448.1 hypothetical protein 833217 3164989 stu0912 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139393.1 832876 D 264199 CDS YP_139394.1 55820952 3165123 complement(833152..833568) 1 NC_006448.1 hypothetical protein 833568 3165123 stu0913 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139394.1 833152 R 264199 CDS YP_139395.1 55820953 3164951 833656..833778 1 NC_006448.1 truncated; hypothetical protein 833778 3164951 stu0914 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139395.1 833656 D 264199 CDS YP_139396.1 55820954 3164717 833841..834086 1 NC_006448.1 truncated; hypothetical protein 834086 3164717 stu0915 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139396.1 833841 D 264199 CDS YP_139397.1 55820955 3164300 834195..834530 1 NC_006448.1 transcriptional regulator 834530 3164300 stu0916 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139397.1 834195 D 264199 CDS YP_139398.1 55820956 3164209 834855..835721 1 NC_006448.1 MutR family transcriptional regulator 835721 3164209 stu0917 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_139398.1 834855 D 264199 CDS YP_139399.1 55820957 3164289 835781..836581 1 NC_006448.1 hypothetical protein 836581 3164289 stu0918 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139399.1 835781 D 264199 CDS YP_139400.1 55820958 3164510 836626..836790 1 NC_006448.1 hypothetical protein 836790 3164510 stu0919 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139400.1 836626 D 264199 CDS YP_139401.1 55820959 3165137 836992..838089 1 NC_006448.1 metallo cofactor biosynthesis protein 838089 3165137 stu0920 Streptococcus thermophilus LMG 18311 metallo cofactor biosynthesis protein YP_139401.1 836992 D 264199 CDS YP_139402.1 55820960 3164823 838086..838829 1 NC_006448.1 agmatinase 838829 speB 3164823 speB Streptococcus thermophilus LMG 18311 agmatinase YP_139402.1 838086 D 264199 CDS YP_139403.1 55820961 3165155 838860..840008 1 NC_006448.1 hypothetical protein 840008 3165155 stu0922 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139403.1 838860 D 264199 CDS YP_139404.1 55820962 3163821 840256..841938 1 NC_006448.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 841938 als 3163821 als Streptococcus thermophilus LMG 18311 acetolactate synthase YP_139404.1 840256 D 264199 CDS YP_139405.1 55820963 3164525 841954..842673 1 NC_006448.1 alpha-acetolactate decarboxylase 842673 aldB 3164525 aldB Streptococcus thermophilus LMG 18311 alpha-acetolactate decarboxylase YP_139405.1 841954 D 264199 CDS YP_139406.1 55820964 3165052 complement(842852..843835) 1 NC_006448.1 truncated; truncated IS1193 transposase 843835 3165052 stu0925 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139406.1 842852 R 264199 CDS YP_139407.1 55820965 3164258 complement(843822..843983) 1 NC_006448.1 truncated; truncated IS1193 transposase 843983 3164258 stu0926 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139407.1 843822 R 264199 CDS YP_139408.1 55820966 3163863 complement(844200..844394) 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 844394 3163863 stu0927 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139408.1 844200 R 264199 CDS YP_139409.1 55820967 3165175 complement(844372..844944) 1 NC_006448.1 truncated; ABC transporter membrane-spanning protein, truncated 844944 3165175 stu0928 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein, truncated YP_139409.1 844372 R 264199 CDS YP_139410.1 55820968 3163848 845166..845918 1 NC_006448.1 short chain dehydrogenase/reductase family oxidoreductase 845918 3163848 stu0929 Streptococcus thermophilus LMG 18311 short chain dehydrogenase/reductase family oxidoreductase YP_139410.1 845166 D 264199 CDS YP_139411.1 55820969 3163870 complement(846095..846307) 1 NC_006448.1 hypothetical protein 846307 3163870 stu0930 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139411.1 846095 R 264199 CDS YP_139412.1 55820970 3165026 complement(846346..846885) 1 NC_006448.1 TetR family transcriptional regulator 846885 3165026 stu0931 Streptococcus thermophilus LMG 18311 TetR family transcriptional regulator YP_139412.1 846346 R 264199 CDS YP_139413.1 55820971 3165093 847019..847915 1 NC_006448.1 cation diffusion facilitor (CDF) family protein 847915 3165093 stu0932 Streptococcus thermophilus LMG 18311 cation diffusion facilitor (CDF) family protein YP_139413.1 847019 D 264199 CDS YP_139414.1 55820972 3164449 848027..848338 1 NC_006448.1 truncated; ferrochelatase 848338 3164449 stu0934 Streptococcus thermophilus LMG 18311 ferrochelatase YP_139414.1 848027 D 264199 CDS YP_139415.1 55820973 3165054 848339..849121 1 NC_006448.1 truncated; ferrochelatase 849121 3165054 stu0935 Streptococcus thermophilus LMG 18311 ferrochelatase YP_139415.1 848339 D 264199 CDS YP_139416.1 55820974 3165065 849218..850255 1 NC_006448.1 alcohol dehydrogenase 850255 adhB 3165065 adhB Streptococcus thermophilus LMG 18311 alcohol dehydrogenase YP_139416.1 849218 D 264199 CDS YP_139417.1 55820975 3165037 850669..850848 1 NC_006448.1 truncated; hypothetical protein 850848 3165037 stu0937 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139417.1 850669 D 264199 CDS YP_139418.1 55820976 3165606 850927..851376 1 NC_006448.1 truncated; hypothetical protein 851376 3165606 stu0938 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139418.1 850927 D 264199 CDS YP_139419.1 55820977 3164182 851838..852290 1 NC_006448.1 hypothetical protein 852290 3164182 stu0940 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139419.1 851838 D 264199 CDS YP_139420.1 55820978 3164534 852636..853400 1 NC_006448.1 phosphorylase Pnp/Udp family protein 853400 3164534 stu0941 Streptococcus thermophilus LMG 18311 phosphorylase Pnp/Udp family protein YP_139420.1 852636 D 264199 CDS YP_139421.1 55820979 3164331 complement(853462..854109) 1 NC_006448.1 phosphatase 854109 3164331 stu0942 Streptococcus thermophilus LMG 18311 phosphatase YP_139421.1 853462 R 264199 CDS YP_139422.1 55820980 3163737 854385..854516 1 NC_006448.1 truncated; ferrichrome ABC transporter substrate-binding protein 854516 3163737 stu0943 Streptococcus thermophilus LMG 18311 ferrichrome ABC transporter substrate-binding protein YP_139422.1 854385 D 264199 CDS YP_139423.1 55820981 3165067 854559..854834 1 NC_006448.1 hypothetical protein 854834 3165067 stu0944 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139423.1 854559 D 264199 CDS YP_139424.1 55820982 3164231 complement(855112..855378) 1 NC_006448.1 truncated; hypothetical protein 855378 3164231 stu0946 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139424.1 855112 R 264199 CDS YP_139425.1 55820983 3164521 complement(855375..855932) 1 NC_006448.1 truncated; hypothetical protein 855932 3164521 stu0947 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139425.1 855375 R 264199 CDS YP_139426.1 55820984 3164687 complement(855974..856222) 1 NC_006448.1 truncated; hypothetical protein 856222 3164687 stu0948 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139426.1 855974 R 264199 CDS YP_139427.1 55820985 3165069 856483..856692 1 NC_006448.1 hypothetical protein 856692 3165069 stu0949 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139427.1 856483 D 264199 CDS YP_139428.1 55820986 3165079 complement(857068..858726) 1 NC_006448.1 fibronectin-binding protein-like protein A 858726 fbp 3165079 fbp Streptococcus thermophilus LMG 18311 fibronectin-binding protein-like protein A YP_139428.1 857068 R 264199 CDS YP_139429.1 55820987 3164752 859044..859601 1 NC_006448.1 hypothetical protein 859601 3164752 stu0951 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139429.1 859044 D 264199 CDS YP_139430.1 55820988 3165290 859868..860416 1 NC_006448.1 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme 860416 thiJ 3165290 thiJ Streptococcus thermophilus LMG 18311 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme YP_139430.1 859868 D 264199 CDS YP_139431.1 55820989 3165329 860658..861461 1 NC_006448.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 861461 pyrK 3165329 pyrK Streptococcus thermophilus LMG 18311 dihydroorotate dehydrogenase electron transfer subunit YP_139431.1 860658 D 264199 CDS YP_139432.1 55820990 3164506 861480..862427 1 NC_006448.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 862427 pyrDb 3164506 pyrDb Streptococcus thermophilus LMG 18311 dihydroorotate dehydrogenase 1B YP_139432.1 861480 D 264199 CDS YP_139433.1 55820991 3165546 862566..863189 1 NC_006448.1 hypothetical protein 863189 3165546 stu0956 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139433.1 862566 D 264199 CDS YP_139434.1 55820992 3164878 863174..863569 1 NC_006448.1 hypothetical protein 863569 3164878 stu0957 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139434.1 863174 D 264199 CDS YP_139435.1 55820993 3164881 863569..863898 1 NC_006448.1 hypothetical protein 863898 3164881 stu0958 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139435.1 863569 D 264199 CDS YP_139436.1 55820994 3164455 864454..865185 1 NC_006448.1 hypothetical protein 865185 3164455 stu0959 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139436.1 864454 D 264199 CDS YP_139437.1 55820995 3164305 865166..867442 1 NC_006448.1 hypothetical protein 867442 3164305 stu0960 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139437.1 865166 D 264199 CDS YP_139438.1 55820996 3164157 867446..867826 1 NC_006448.1 hypothetical protein 867826 3164157 stu0961 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139438.1 867446 D 264199 CDS YP_139439.1 55820997 3164164 867826..868488 1 NC_006448.1 hypothetical protein 868488 3164164 stu0962 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139439.1 867826 D 264199 CDS YP_139440.1 55820998 3164129 868490..869389 1 NC_006448.1 hypothetical protein 869389 3164129 stu0963 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139440.1 868490 D 264199 CDS YP_139441.1 55820999 3164354 869392..870465 1 NC_006448.1 hypothetical protein 870465 3164354 stu0964 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139441.1 869392 D 264199 CDS YP_139442.1 55821000 3165041 870620..870736 1 NC_006448.1 truncated; hypothetical protein 870736 3165041 stu0965 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139442.1 870620 D 264199 CDS YP_139443.1 55821001 3165146 870767..871795 1 NC_006448.1 truncated; hypothetical protein 871795 3165146 stu0966 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139443.1 870767 D 264199 CDS YP_139444.1 55821002 3163874 871995..872690 1 NC_006448.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 872690 pyrF 3163874 pyrF Streptococcus thermophilus LMG 18311 orotidine 5'-phosphate decarboxylase YP_139444.1 871995 D 264199 CDS YP_139445.1 55821003 3164313 872779..873408 1 NC_006448.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 873408 pyrE 3164313 pyrE Streptococcus thermophilus LMG 18311 orotate phosphoribosyltransferase YP_139445.1 872779 D 264199 CDS YP_139446.1 55821004 3164265 873649..874056 1 NC_006448.1 truncated; amidase 874056 3164265 stu0969 Streptococcus thermophilus LMG 18311 amidase YP_139446.1 873649 D 264199 CDS YP_139447.1 55821005 3164310 complement(874107..875558) 1 NC_006448.1 di- or tripeptide:H+ symporter 875558 dtpT 3164310 dtpT Streptococcus thermophilus LMG 18311 di- or tripeptide:H+ symporter YP_139447.1 874107 R 264199 CDS YP_139448.1 55821006 3163853 875897..876937 1 NC_006448.1 IS1239 transposase 876937 tnp1239 3163853 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_139448.1 875897 D 264199 CDS YP_139449.1 55821007 3164097 877223..877825 1 NC_006448.1 truncated; amidase 877825 3164097 stu0973 Streptococcus thermophilus LMG 18311 amidase YP_139449.1 877223 D 264199 CDS YP_139450.1 55821008 3164328 877914..878348 1 NC_006448.1 truncated; amino acid ABC transporter substrate-binding protein 878348 3164328 stu0974 Streptococcus thermophilus LMG 18311 amino acid ABC transporter substrate-binding protein YP_139450.1 877914 D 264199 CDS YP_139451.1 55821009 3164566 878368..878727 1 NC_006448.1 truncated; amino acid ABC transporter substrate-binding protein 878727 3164566 stu0975 Streptococcus thermophilus LMG 18311 amino acid ABC transporter substrate-binding protein YP_139451.1 878368 D 264199 CDS YP_139452.1 55821010 3164488 878866..879279 1 NC_006448.1 truncated; amino acid ABC uptake transporter membrane-spanning protein, truncated 879279 3164488 stu0976 Streptococcus thermophilus LMG 18311 amino acid ABC uptake transporter membrane-spanning protein, truncated YP_139452.1 878866 D 264199 CDS YP_139453.1 55821011 3164450 879249..879437 1 NC_006448.1 truncated; amino acid ABC uptake transporter membrane-spanning protein, truncated 879437 3164450 stu0977 Streptococcus thermophilus LMG 18311 amino acid ABC uptake transporter membrane-spanning protein, truncated YP_139453.1 879249 D 264199 CDS YP_139454.1 55821012 3164267 879567..879800 1 NC_006448.1 hypothetical protein 879800 3164267 stu0978 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139454.1 879567 D 264199 CDS YP_139455.1 55821013 3164422 879874..881340 1 NC_006448.1 5'-nucleotidase 881340 3164422 stu0979 Streptococcus thermophilus LMG 18311 5'-nucleotidase YP_139455.1 879874 D 264199 CDS YP_139456.1 55821014 3164477 881351..881638 1 NC_006448.1 hypothetical protein 881638 3164477 stu0980 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139456.1 881351 D 264199 CDS YP_139457.1 55821015 3165078 complement(881848..882456) 1 NC_006448.1 truncated; AraC family transcriptional regulator 882456 3165078 stu0981 Streptococcus thermophilus LMG 18311 AraC family transcriptional regulator YP_139457.1 881848 R 264199 CDS YP_139458.1 55821016 3163921 complement(882681..882815) 1 NC_006448.1 truncated; AraC family transcriptional regulator 882815 3163921 stu0982 Streptococcus thermophilus LMG 18311 AraC family transcriptional regulator YP_139458.1 882681 R 264199 CDS YP_139459.1 55821017 3163882 complement(882931..884301) 1 NC_006448.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 884301 trmE 3163882 trmE Streptococcus thermophilus LMG 18311 tRNA modification GTPase TrmE YP_139459.1 882931 R 264199 CDS YP_139460.1 55821018 3163974 complement(884430..885773) 1 NC_006448.1 alanine (or glycine):Na+ symporter 885773 dagA 3163974 dagA Streptococcus thermophilus LMG 18311 alanine (or glycine):Na+ symporter YP_139460.1 884430 R 264199 CDS YP_139461.1 55821019 3164003 886271..888598 1 NC_006448.1 ATP-dependent DNA helicase 888598 pcrA 3164003 pcrA Streptococcus thermophilus LMG 18311 ATP-dependent DNA helicase YP_139461.1 886271 D 264199 CDS YP_139462.1 55821020 3164451 888686..889999 1 NC_006448.1 O-acetylhomoserine sulfhydrylase 889999 cysD 3164451 cysD Streptococcus thermophilus LMG 18311 O-acetylhomoserine sulfhydrylase YP_139462.1 888686 D 264199 CDS YP_139463.1 55821021 3164285 890060..890401 1 NC_006448.1 truncated; hypothetical protein 890401 3164285 stu0988 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139463.1 890060 D 264199 CDS YP_139464.1 55821022 3163741 890447..890815 1 NC_006448.1 truncated; hypothetical protein 890815 3163741 stu0989 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139464.1 890447 D 264199 CDS YP_139465.1 55821023 3163746 890880..891374 1 NC_006448.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 891374 tpx 3163746 tpx Streptococcus thermophilus LMG 18311 thiol peroxidase YP_139465.1 890880 D 264199 CDS YP_139466.1 55821024 3165451 891497..892117 1 NC_006448.1 type I restriction-modification system specificty subunit 892117 hsdS2 3165451 hsdS2 Streptococcus thermophilus LMG 18311 type I restriction-modification system specificty subunit YP_139466.1 891497 D 264199 CDS YP_139467.1 55821025 3164160 892138..892341 1 NC_006448.1 hypothetical protein 892341 3164160 stu0992 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139467.1 892138 D 264199 CDS YP_139468.1 55821026 3165057 892355..893140 1 NC_006448.1 truncated; hypothetical protein 893140 3165057 stu0993 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139468.1 892355 D 264199 CDS YP_139469.1 55821027 3164101 893515..893670 1 NC_006448.1 truncated; hypothetical protein 893670 3164101 stu0994 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139469.1 893515 D 264199 CDS YP_139470.1 55821028 3164162 893792..894673 1 NC_006448.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 894673 truB 3164162 truB Streptococcus thermophilus LMG 18311 tRNA pseudouridine synthase B YP_139470.1 893792 D 264199 CDS YP_139471.1 55821029 3164865 894670..895581 1 NC_006448.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 895581 ribC 3164865 ribC Streptococcus thermophilus LMG 18311 bifunctional riboflavin kinase/FMN adenylyltransferase YP_139471.1 894670 D 264199 CDS YP_139472.1 55821030 3165055 895652..896065 1 NC_006448.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 896065 spxA 3165055 spxA Streptococcus thermophilus LMG 18311 transcriptional regulator Spx YP_139472.1 895652 D 264199 CDS YP_139473.1 55821031 3164512 896058..896339 1 NC_006448.1 hypothetical protein 896339 3164512 stu0998 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139473.1 896058 D 264199 CDS YP_139474.1 55821032 3165127 896329..897096 1 NC_006448.1 inositol monophosphatase 897096 suhB 3165127 suhB Streptococcus thermophilus LMG 18311 inositol monophosphatase YP_139474.1 896329 D 264199 CDS YP_139475.1 55821033 3163975 897148..898488 1 NC_006448.1 rRNA methyltransferase 898488 3163975 stu1000 Streptococcus thermophilus LMG 18311 rRNA methyltransferase YP_139475.1 897148 D 264199 CDS YP_139476.1 55821034 3164719 898589..899488 1 NC_006448.1 phosphate ABC uptake transporter substrate binding protein 899488 pstS 3164719 pstS Streptococcus thermophilus LMG 18311 phosphate ABC uptake transporter substrate binding protein YP_139476.1 898589 D 264199 CDS YP_139477.1 55821035 3165085 899491..900405 1 NC_006448.1 phosphate ABC uptake transporter membrane-spanning protein 900405 pstC1 3165085 pstC1 Streptococcus thermophilus LMG 18311 phosphate ABC uptake transporter membrane-spanning protein YP_139477.1 899491 D 264199 CDS YP_139478.1 55821036 3165131 900377..901279 1 NC_006448.1 phosphate ABC uptake transporter membrane-spanning protein 901279 pstC2 3165131 pstC2 Streptococcus thermophilus LMG 18311 phosphate ABC uptake transporter membrane-spanning protein YP_139478.1 900377 D 264199 CDS YP_139479.1 55821037 3164544 901290..902093 1 NC_006448.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 902093 pstB1 3164544 pstB1 Streptococcus thermophilus LMG 18311 phosphate transporter ATP-binding protein YP_139479.1 901290 D 264199 CDS YP_139480.1 55821038 3164712 902106..902864 1 NC_006448.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 902864 pstB2 3164712 pstB2 Streptococcus thermophilus LMG 18311 phosphate transporter ATP-binding protein YP_139480.1 902106 D 264199 CDS YP_139481.1 55821039 3164458 902889..903545 1 NC_006448.1 phosphate uptake regulatory protein 903545 phoU 3164458 phoU Streptococcus thermophilus LMG 18311 phosphate uptake regulatory protein YP_139481.1 902889 D 264199 CDS YP_139482.1 55821040 3164246 903679..906219 1 NC_006448.1 lysyl-aminopeptidase, aminopeptidase N 906219 pepN 3164246 pepN Streptococcus thermophilus LMG 18311 lysyl-aminopeptidase, aminopeptidase N YP_139482.1 903679 D 264199 CDS YP_139483.1 55821041 3164628 complement(906381..907451) 1 NC_006448.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 907451 xerS 3164628 xerS Streptococcus thermophilus LMG 18311 site-specific tyrosine recombinase XerS YP_139483.1 906381 R 264199 CDS YP_139484.1 55821042 3163924 complement(907676..908665) 1 NC_006448.1 lipoate-protein ligase 908665 lplA 3163924 lplA Streptococcus thermophilus LMG 18311 lipoate-protein ligase YP_139484.1 907676 R 264199 CDS YP_139485.1 55821043 3165355 908848..909402 1 NC_006448.1 hypothetical protein 909402 3165355 stu1010 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139485.1 908848 D 264199 CDS YP_139486.1 55821044 3164484 909471..909899 1 NC_006448.1 hypothetical protein 909899 3164484 stu1011 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139486.1 909471 D 264199 CDS YP_139487.1 55821045 3164124 complement(910005..912269) 1 NC_006448.1 glycogen phosphorylase 912269 glgP 3164124 glgP Streptococcus thermophilus LMG 18311 glycogen phosphorylase YP_139487.1 910005 R 264199 CDS YP_139488.1 55821046 3164871 complement(912271..913779) 1 NC_006448.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 913779 malQ 3164871 malQ Streptococcus thermophilus LMG 18311 4-alpha-glucanotransferase YP_139488.1 912271 R 264199 CDS YP_139489.1 55821047 3164990 complement(913963..914967) 1 NC_006448.1 maltose operon transcriptional repressor 914967 malR 3164990 malR Streptococcus thermophilus LMG 18311 maltose operon transcriptional repressor YP_139489.1 913963 R 264199 CDS YP_139490.1 55821048 3164524 915314..915454 1 NC_006448.1 truncated; maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated 915454 3164524 stu1015 Streptococcus thermophilus LMG 18311 maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated YP_139490.1 915314 D 264199 CDS YP_139491.1 55821049 3164439 915626..916012 1 NC_006448.1 truncated; maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated 916012 3164439 stu1016 Streptococcus thermophilus LMG 18311 maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated YP_139491.1 915626 D 264199 CDS YP_139492.1 55821050 3163738 916026..916706 1 NC_006448.1 truncated; maltose/maltodextrin ABC uptake transporter membrane-spanning protein, truncated 916706 3163738 stu1017 Streptococcus thermophilus LMG 18311 maltose/maltodextrin ABC uptake transporter membrane-spanning protein, truncated YP_139492.1 916026 D 264199 CDS YP_139493.1 55821051 3164549 complement(917353..917541) 1 NC_006448.1 Sec-independent protein translocase protein tatA 917541 tatA 3164549 tatA Streptococcus thermophilus LMG 18311 Sec-independent protein translocase protein tatA YP_139493.1 917353 R 264199 CDS YP_139494.1 55821052 3164090 complement(917554..918282) 1 NC_006448.1 Sec-independent protein translocase protein tatC 918282 tatC 3164090 tatC Streptococcus thermophilus LMG 18311 Sec-independent protein translocase protein tatC YP_139494.1 917554 R 264199 CDS YP_139495.1 55821053 3164690 complement(918269..919990) 1 NC_006448.1 hypothetical protein 919990 3164690 stu1022 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139495.1 918269 R 264199 CDS YP_139496.1 55821054 3163795 complement(919932..921137) 1 NC_006448.1 hypothetical protein 921137 3163795 stu1023 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139496.1 919932 R 264199 CDS YP_139497.1 55821055 3164887 complement(921143..921970) 1 NC_006448.1 hypothetical protein 921970 3164887 stu1024 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139497.1 921143 R 264199 CDS YP_139498.1 55821056 3165213 complement(922277..923323) 1 NC_006448.1 iron ABC transporter substrate-binding protein 923323 fatB 3165213 fatB Streptococcus thermophilus LMG 18311 iron ABC transporter substrate-binding protein YP_139498.1 922277 R 264199 CDS YP_139499.1 55821057 3164808 complement(923335..924090) 1 NC_006448.1 iron compound ABC uptake transporter ATP-binding protein 924090 fatA 3164808 fatA Streptococcus thermophilus LMG 18311 iron compound ABC uptake transporter ATP-binding protein YP_139499.1 923335 R 264199 CDS YP_139500.1 55821058 3165075 complement(924087..925073) 1 NC_006448.1 iron compound ABC uptake transporter membrane-spanning protein 925073 fatC 3165075 fatC Streptococcus thermophilus LMG 18311 iron compound ABC uptake transporter membrane-spanning protein YP_139500.1 924087 R 264199 CDS YP_139501.1 55821059 3164254 complement(925052..926026) 1 NC_006448.1 iron compound ABC uptake transporter membrane-spanning protein 926026 fatD 3164254 fatD Streptococcus thermophilus LMG 18311 iron compound ABC uptake transporter membrane-spanning protein YP_139501.1 925052 R 264199 CDS YP_139502.1 55821060 3164269 complement(926504..926773) 1 NC_006448.1 truncated; alkaline amylopullulanase, truncated 926773 3164269 stu1029 Streptococcus thermophilus LMG 18311 alkaline amylopullulanase, truncated YP_139502.1 926504 R 264199 CDS YP_139503.1 55821061 3163865 complement(926776..927390) 1 NC_006448.1 truncated; alkaline amylopullulanase, truncated 927390 3163865 stu1031 Streptococcus thermophilus LMG 18311 alkaline amylopullulanase, truncated YP_139503.1 926776 R 264199 CDS YP_139504.1 55821062 3163857 complement(927454..927564) 1 NC_006448.1 truncated; alkaline amylopullulanase, truncated 927564 3163857 stu1032 Streptococcus thermophilus LMG 18311 alkaline amylopullulanase, truncated YP_139504.1 927454 R 264199 CDS YP_139505.1 55821063 3165061 complement(927497..928564) 1 NC_006448.1 truncated; alkaline amylopullulanase, truncated 928564 3165061 stu1033 Streptococcus thermophilus LMG 18311 alkaline amylopullulanase, truncated YP_139505.1 927497 R 264199 CDS YP_139506.1 55821064 3165366 complement(928583..928687) 1 NC_006448.1 truncated; alkaline amylopullulanase, truncated 928687 3165366 stu1034 Streptococcus thermophilus LMG 18311 alkaline amylopullulanase, truncated YP_139506.1 928583 R 264199 CDS YP_139507.1 55821065 3164564 929095..930183 1 NC_006448.1 IS1191 transposase 930183 tnp1191 3164564 tnp1191 Streptococcus thermophilus LMG 18311 IS1191 transposase YP_139507.1 929095 D 264199 CDS YP_139508.1 55821066 3164461 complement(930218..930565) 1 NC_006448.1 truncated; UDP-N-acetylglucosamine enolpyruvyl transferase, truncated 930565 3164461 stu1041 Streptococcus thermophilus LMG 18311 UDP-N-acetylglucosamine enolpyruvyl transferase, truncated YP_139508.1 930218 R 264199 CDS YP_139509.1 55821067 3164326 complement(930567..931133) 1 NC_006448.1 hypothetical protein 931133 3164326 stu1042 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139509.1 930567 R 264199 CDS YP_139510.1 55821068 3165091 complement(931927..932835) 1 NC_006448.1 tyrosyl-tRNA synthetase E 932835 tyrSE 3165091 tyrSE Streptococcus thermophilus LMG 18311 tyrosyl-tRNA synthetase E YP_139510.1 931927 R 264199 CDS YP_139511.1 55821069 3164159 933089..933943 1 NC_006448.1 MutR family transcriptional regulator 933943 3164159 stu1044 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_139511.1 933089 D 264199 CDS YP_139512.1 55821070 3164440 complement(934110..935366) 1 NC_006448.1 IS1193 transposase 935366 tnp1193 3164440 tnp1193 Streptococcus thermophilus LMG 18311 IS1193 transposase YP_139512.1 934110 R 264199 CDS YP_139513.1 55821071 3165173 complement(935851..936246) 1 NC_006448.1 truncated; endolysin, truncated 936246 3165173 stu1046 Streptococcus thermophilus LMG 18311 endolysin, truncated YP_139513.1 935851 R 264199 CDS YP_139514.1 55821072 3163817 complement(936362..936631) 1 NC_006448.1 hypothetical protein 936631 3163817 stu1047 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139514.1 936362 R 264199 CDS YP_139515.1 55821073 3164479 complement(936948..938702) 1 NC_006448.1 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 938702 acoL 3164479 acoL Streptococcus thermophilus LMG 18311 acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase YP_139515.1 936948 R 264199 CDS YP_139516.1 55821074 3163980 complement(938873..940261) 1 NC_006448.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 940261 acoC 3163980 acoC Streptococcus thermophilus LMG 18311 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_139516.1 938873 R 264199 CDS YP_139517.1 55821075 3165156 complement(940419..941432) 1 NC_006448.1 acetoin dehydrogenase complex, E1 component subunit beta 941432 acoB 3165156 acoB Streptococcus thermophilus LMG 18311 acetoin dehydrogenase complex, E1 component subunit beta YP_139517.1 940419 R 264199 CDS YP_139518.1 55821076 3164108 complement(941442..942413) 1 NC_006448.1 acetoin dehydrogenase complex, E1 component subunit alpha 942413 acoA 3164108 acoA Streptococcus thermophilus LMG 18311 acetoin dehydrogenase complex, E1 component subunit alpha YP_139518.1 941442 R 264199 CDS YP_139519.1 55821077 3164470 complement(942903..943211) 1 NC_006448.1 truncated; hypothetical protein 943211 3164470 stu1052 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139519.1 942903 R 264199 CDS YP_139520.1 55821078 3164333 complement(943467..943988) 1 NC_006448.1 truncated; hypothetical protein 943988 3164333 stu1053 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139520.1 943467 R 264199 CDS YP_139521.1 55821079 3164436 complement(944180..945448) 1 NC_006448.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 945448 pyrC 3164436 pyrC Streptococcus thermophilus LMG 18311 dihydroorotase YP_139521.1 944180 R 264199 CDS YP_139522.1 55821080 3165071 complement(945468..946148) 1 NC_006448.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 946148 ung 3165071 ung Streptococcus thermophilus LMG 18311 uracil-DNA glycosylase YP_139522.1 945468 R 264199 CDS YP_139523.1 55821081 3165281 946335..947531 1 NC_006448.1 hypothetical protein 947531 3165281 stu1056 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139523.1 946335 D 264199 CDS YP_139524.1 55821082 3165424 947804..947971 1 NC_006448.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 947971 3165424 stu1057 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_139524.1 947804 D 264199 CDS YP_139525.1 55821083 3164016 947952..948134 1 NC_006448.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 948134 3164016 stu1058 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_139525.1 947952 D 264199 CDS YP_139526.1 55821084 3164716 948156..949097 1 NC_006448.1 truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 949097 3164716 stu1059 Streptococcus thermophilus LMG 18311 D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated YP_139526.1 948156 D 264199 CDS YP_139527.1 55821085 3164702 complement(949137..949988) 1 NC_006448.1 phosphoesterase 949988 3164702 stu1060 Streptococcus thermophilus LMG 18311 phosphoesterase YP_139527.1 949137 R 264199 CDS YP_139528.1 55821086 3164730 complement(949985..950473) 1 NC_006448.1 hypothetical protein 950473 3164730 stu1061 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139528.1 949985 R 264199 CDS YP_139529.1 55821087 3165598 complement(950608..952185) 1 NC_006448.1 hypothetical protein 952185 3165598 stu1062 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139529.1 950608 R 264199 CDS YP_139530.1 55821088 3164797 complement(952203..952487) 1 NC_006448.1 hypothetical protein 952487 3164797 stu1063 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139530.1 952203 R 264199 CDS YP_139531.1 55821089 3164042 complement(952735..952965) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 952965 3164042 stu1064 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_139531.1 952735 R 264199 CDS YP_139532.1 55821090 3164561 complement(952962..953207) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 953207 3164561 stu1065 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_139532.1 952962 R 264199 CDS YP_139533.1 55821091 3165325 complement(953243..953779) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 953779 3165325 stu1066 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_139533.1 953243 R 264199 CDS YP_139534.1 55821092 3164299 complement(953806..954003) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 954003 3164299 stu1067 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_139534.1 953806 R 264199 CDS YP_139535.1 55821093 3165182 complement(954247..955383) 1 NC_006448.1 hypothetical protein 955383 3165182 stu1068 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139535.1 954247 R 264199 CDS YP_139536.1 55821094 3164014 complement(955462..955689) 1 NC_006448.1 truncated; hypothetical protein 955689 3164014 stu1069 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139536.1 955462 R 264199 CDS YP_139537.1 55821095 3164330 complement(955714..955977) 1 NC_006448.1 truncated; hypothetical protein 955977 3164330 stu1070 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139537.1 955714 R 264199 CDS YP_139538.1 55821096 3164771 complement(956073..956468) 1 NC_006448.1 truncated; hypothetical protein 956468 3164771 stu1071 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139538.1 956073 R 264199 CDS YP_139539.1 55821097 3165540 957092..957667 1 NC_006448.1 hypothetical protein 957667 3165540 stu1075 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139539.1 957092 D 264199 CDS YP_139540.1 55821098 3164590 957830..959086 1 NC_006448.1 IS1193 transposase 959086 tnp1193 3164590 tnp1193 Streptococcus thermophilus LMG 18311 IS1193 transposase YP_139540.1 957830 D 264199 CDS YP_139541.1 55821100 3164295 complement(959094..959726) 1 NC_006448.1 truncated; hypothetical protein 959726 3164295 stu1088 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139541.1 959094 R 264199 CDS YP_139542.1 55821099 3164610 959678..960529 1 NC_006448.1 truncated; hypothetical protein 960529 3164610 stu1087 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139542.1 959678 D 264199 CDS YP_139543.1 55821101 3164062 complement(960557..961177) 1 NC_006448.1 hypothetical protein 961177 3164062 stu1089 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139543.1 960557 R 264199 CDS YP_139544.1 55821102 3164791 complement(961247..961948) 1 NC_006448.1 hypothetical protein 961948 3164791 stu1090 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139544.1 961247 R 264199 CDS YP_139545.1 55821103 3164582 complement(963149..963907) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyl transferase 963907 epsK 3164582 epsK Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyl transferase YP_139545.1 963149 R 264199 CDS YP_139546.1 55821104 3163896 complement(963894..965012) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyl transferase 965012 eps15 3163896 eps15 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyl transferase YP_139546.1 963894 R 264199 CDS YP_139547.1 55821106 3165488 complement(965123..965746) 1 NC_006448.1 hypothetical protein 965746 eps14 3165488 eps14 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139547.1 965123 R 264199 CDS YP_139548.1 55821105 3164486 965241..965897 1 NC_006448.1 hypothetical protein 965897 3164486 stu1093 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139548.1 965241 D 264199 CDS YP_139549.1 55821107 3164491 complement(965887..967062) 1 NC_006448.1 exopolysaccharide biosynthesis protein 967062 eps13 3164491 eps13 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein YP_139549.1 965887 R 264199 CDS YP_139550.1 55821108 3164686 complement(967069..968568) 1 NC_006448.1 exopolysaccharide biosynthesis protein, membrane protein 968568 eps12 3164686 eps12 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, membrane protein YP_139550.1 967069 R 264199 CDS YP_139551.1 55821109 3165234 complement(968965..969957) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 969957 eps11 3165234 eps11 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_139551.1 968965 R 264199 CDS YP_139552.1 55821110 3164811 complement(969982..970722) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 970722 eps10 3164811 eps10 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_139552.1 969982 R 264199 CDS YP_139553.1 55821111 3164806 complement(970775..971332) 1 NC_006448.1 exopolysaccharide biosynthesis protein 971332 eps9 3164806 eps9 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein YP_139553.1 970775 R 264199 CDS YP_139554.1 55821112 3164626 complement(971804..972451) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 972451 eps15 3164626 eps15 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_139554.1 971804 R 264199 CDS YP_139555.1 55821113 3164260 complement(972488..972820) 1 NC_006448.1 hypothetical protein 972820 3164260 stu1101 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139555.1 972488 R 264199 CDS YP_139556.1 55821114 3164008 complement(973462..974313) 1 NC_006448.1 hypothetical protein 974313 3164008 stu1102 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139556.1 973462 R 264199 CDS YP_139557.1 55821115 3163902 complement(974456..974935) 1 NC_006448.1 exopolysaccharide biosynthesis protein 974935 eps4 3163902 eps4 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein YP_139557.1 974456 R 264199 CDS YP_139558.1 55821116 3163770 complement(975038..975523) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 975523 eps3 3163770 eps3 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_139558.1 975038 R 264199 CDS YP_139559.1 55821117 3164089 complement(975523..975972) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyltransferase 975972 eps2 3164089 eps2 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyltransferase YP_139559.1 975523 R 264199 CDS YP_139560.1 55821118 3164780 complement(975981..976400) 1 NC_006448.1 truncated; exopolysaccharide biosynthesis protein, truncated 976400 3164780 stu1106 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, truncated YP_139560.1 975981 R 264199 CDS YP_139561.1 55821119 3164213 complement(976420..977004) 1 NC_006448.1 truncated; exopolysaccharide biosynthesis protein, truncated 977004 3164213 stu1107 Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, truncated YP_139561.1 976420 R 264199 CDS YP_139562.1 55821120 3164721 complement(977206..978573) 1 NC_006448.1 exopolysaccharide biosynthesis protein, glycosyl-1-phosphate transferase 978573 epsE 3164721 epsE Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein, glycosyl-1-phosphate transferase YP_139562.1 977206 R 264199 CDS YP_139563.1 55821121 3163890 complement(978630..979370) 1 NC_006448.1 exopolysaccharide exporter accessory protein 979370 epsD 3163890 epsD Streptococcus thermophilus LMG 18311 exopolysaccharide exporter accessory protein YP_139563.1 978630 R 264199 CDS YP_139564.1 55821122 3164972 complement(979380..980072) 1 NC_006448.1 exopolysaccharide exporter accessory protein 980072 epsC 3164972 epsC Streptococcus thermophilus LMG 18311 exopolysaccharide exporter accessory protein YP_139564.1 979380 R 264199 CDS YP_139565.1 55821123 3164851 complement(980081..980812) 1 NC_006448.1 exopolysaccharide biosynthesis protein 980812 epsB 3164851 epsB Streptococcus thermophilus LMG 18311 exopolysaccharide biosynthesis protein YP_139565.1 980081 R 264199 CDS YP_139566.1 55821124 3164290 complement(980813..982267) 1 NC_006448.1 transcriptional activator-exopolysaccharide biosynthesis 982267 epsA 3164290 epsA Streptococcus thermophilus LMG 18311 transcriptional activator-exopolysaccharide biosynthesis YP_139566.1 980813 R 264199 CDS YP_139567.1 55821125 3165036 complement(982613..983323) 1 NC_006448.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 983323 deoD 3165036 deoD Streptococcus thermophilus LMG 18311 purine nucleoside phosphorylase YP_139567.1 982613 R 264199 CDS YP_139568.1 55821126 3164574 complement(983757..984020) 1 NC_006448.1 truncated; glutamine amidotransferase (GMP synthase), truncated 984020 3164574 stu1114 Streptococcus thermophilus LMG 18311 glutamine amidotransferase (GMP synthase), truncated YP_139568.1 983757 R 264199 CDS YP_139569.1 55821127 3164742 complement(984017..984217) 1 NC_006448.1 truncated; glutamine amidotransferase (GMP synthase), truncated 984217 3164742 stu1115 Streptococcus thermophilus LMG 18311 glutamine amidotransferase (GMP synthase), truncated YP_139569.1 984017 R 264199 CDS YP_139570.1 55821128 3165583 complement(984715..985116) 1 NC_006448.1 truncated; voltage-gated chloride channel family protein, truncated 985116 3165583 stu1116 Streptococcus thermophilus LMG 18311 voltage-gated chloride channel family protein, truncated YP_139570.1 984715 R 264199 CDS YP_139571.1 55821129 3163983 complement(985475..986284) 1 NC_006448.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 986284 punA 3163983 punA Streptococcus thermophilus LMG 18311 purine nucleoside phosphorylase YP_139571.1 985475 R 264199 CDS YP_139572.1 55821130 3165517 complement(986305..986724) 1 NC_006448.1 truncated; hypothetical protein 986724 3165517 stu1118 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139572.1 986305 R 264199 CDS YP_139573.1 55821131 3163889 complement(986705..986881) 1 NC_006448.1 truncated; hypothetical protein 986881 3163889 stu1119 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139573.1 986705 R 264199 CDS YP_139574.1 55821132 3164438 complement(986850..988061) 1 NC_006448.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 988061 deoB 3164438 deoB Streptococcus thermophilus LMG 18311 phosphopentomutase YP_139574.1 986850 R 264199 CDS YP_139575.1 55821133 3163991 complement(988187..988867) 1 NC_006448.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 988867 rpiA 3163991 rpiA Streptococcus thermophilus LMG 18311 ribose-5-phosphate isomerase A YP_139575.1 988187 R 264199 CDS YP_139576.1 55821134 3164653 complement(989158..989430) 1 NC_006448.1 hypothetical protein 989430 3164653 stu1122 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139576.1 989158 R 264199 CDS YP_139577.1 55821135 3165090 complement(989496..989654) 1 NC_006448.1 hypothetical protein 989654 3165090 stu1123 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139577.1 989496 R 264199 CDS YP_139578.1 55821136 3165498 complement(989766..991022) 1 NC_006448.1 IS1193 transposase 991022 tnp1193 3165498 tnp1193 Streptococcus thermophilus LMG 18311 IS1193 transposase YP_139578.1 989766 R 264199 CDS YP_139579.1 55821137 3164460 complement(991534..991950) 1 NC_006448.1 hypothetical protein 991950 3164460 stu1125 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139579.1 991534 R 264199 CDS YP_139580.1 55821138 3164625 complement(992308..992874) 1 NC_006448.1 hypothetical protein 992874 3164625 stu1126 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139580.1 992308 R 264199 CDS YP_139581.1 55821139 3165470 complement(992931..994337) 1 NC_006448.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 994337 pepV 3165470 pepV Streptococcus thermophilus LMG 18311 dipeptidase PepV YP_139581.1 992931 R 264199 CDS YP_139582.1 55821140 3164991 994568..994753 1 NC_006448.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 994753 xylH 3164991 xylH Streptococcus thermophilus LMG 18311 4-oxalocrotonate tautomerase YP_139582.1 994568 D 264199 CDS YP_139583.1 55821141 3164570 complement(994829..995302) 1 NC_006448.1 hypothetical protein 995302 3164570 stu1129 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139583.1 994829 R 264199 CDS YP_139584.1 55821142 3164866 complement(995457..995630) 1 NC_006448.1 truncated; hypothetical protein 995630 3164866 stu1130 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139584.1 995457 R 264199 CDS YP_139585.1 55821143 3164773 complement(996096..996455) 1 NC_006448.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 996455 rplT 3164773 rplT Streptococcus thermophilus LMG 18311 50S ribosomal protein L20 YP_139585.1 996096 R 264199 CDS YP_139586.1 55821144 3163883 complement(996512..996712) 1 NC_006448.1 50S ribosomal protein L35 996712 rpmI 3163883 rpmI Streptococcus thermophilus LMG 18311 50S ribosomal protein L35 YP_139586.1 996512 R 264199 CDS YP_139587.1 55821145 3165432 complement(996751..997281) 1 NC_006448.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 997281 infC 3165432 infC Streptococcus thermophilus LMG 18311 translation initiation factor IF-3 YP_139587.1 996751 R 264199 CDS YP_139588.1 55821146 3164901 complement(997441..998121) 1 NC_006448.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 998121 cmk 3164901 cmk Streptococcus thermophilus LMG 18311 cytidylate kinase YP_139588.1 997441 R 264199 CDS YP_139589.1 55821147 3164459 complement(998142..998771) 1 NC_006448.1 hypothetical protein 998771 3164459 stu1136 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139589.1 998142 R 264199 CDS YP_139590.1 55821148 3163828 998817..999014 1 NC_006448.1 ferredoxin 999014 fer 3163828 fer Streptococcus thermophilus LMG 18311 ferredoxin YP_139590.1 998817 D 264199 CDS YP_139591.1 55821149 3163787 complement(998998..999498) 1 NC_006448.1 pore-forming peptide 999498 3163787 stu1138 Streptococcus thermophilus LMG 18311 pore-forming peptide YP_139591.1 998998 R 264199 CDS YP_139592.1 55821150 3165099 complement(999555..1000778) 1 NC_006448.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1000778 pepT 3165099 pepT Streptococcus thermophilus LMG 18311 peptidase T YP_139592.1 999555 R 264199 CDS YP_139593.1 55821151 3164348 complement(1000987..1001544) 1 NC_006448.1 signal peptidase I 1001544 sipB 3164348 sipB Streptococcus thermophilus LMG 18311 signal peptidase I YP_139593.1 1000987 R 264199 CDS YP_139594.1 55821152 3164627 complement(1001667..1002926) 1 NC_006448.1 hypothetical protein 1002926 3164627 stu1141 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139594.1 1001667 R 264199 CDS YP_139595.1 55821153 3164772 complement(1002886..1004064) 1 NC_006448.1 hypothetical protein 1004064 3164772 stu1142 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139595.1 1002886 R 264199 CDS YP_139596.1 55821154 3165482 complement(1004075..1004557) 1 NC_006448.1 7,8-dihydro-8-oxoguanine-triphosphatase 1004557 mutT 3165482 mutT Streptococcus thermophilus LMG 18311 7,8-dihydro-8-oxoguanine-triphosphatase YP_139596.1 1004075 R 264199 CDS YP_139597.1 55821155 3164199 complement(1004713..1005678) 1 NC_006448.1 cell division ABC transporter permease 1005678 ftsX 3164199 ftsX Streptococcus thermophilus LMG 18311 cell division ABC transporter permease YP_139597.1 1004713 R 264199 CDS YP_139598.1 55821156 3164200 complement(1005635..1006342) 1 NC_006448.1 cell division ATP-binding protein 1006342 ftsE 3164200 ftsE Streptococcus thermophilus LMG 18311 cell division ATP-binding protein YP_139598.1 1005635 R 264199 CDS YP_139599.1 55821157 3164203 complement(1006415..1007428) 1 NC_006448.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1007428 prfB 3164203 prfB Streptococcus thermophilus LMG 18311 peptide chain release factor 2 YP_139599.1 1006415 R 264199 CDS YP_139600.1 55821159 3164204 complement(1007566..1008684) 1 NC_006448.1 hypothetical protein 1008684 3164204 stu1148 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139600.1 1007566 R 264199 CDS YP_139601.1 55821158 3164201 1008697..1009641 1 NC_006448.1 hypothetical protein 1009641 3164201 stu1147 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139601.1 1008697 D 264199 CDS YP_139602.1 55821160 3164205 complement(1009665..1010411) 1 NC_006448.1 nitro/flavin reductase 1010411 nfrA 3164205 nfrA Streptococcus thermophilus LMG 18311 nitro/flavin reductase YP_139602.1 1009665 R 264199 CDS YP_139603.1 55821161 3164206 complement(1010520..1013204) 1 NC_006448.1 Ca2+, Mn2+-P-type ATPase 1013204 pacL2 3164206 pacL2 Streptococcus thermophilus LMG 18311 Ca2+, Mn2+-P-type ATPase YP_139603.1 1010520 R 264199 CDS YP_139604.1 55821162 3164390 complement(1013470..1013856) 1 NC_006448.1 hypothetical protein 1013856 3164390 stu1151 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139604.1 1013470 R 264199 CDS YP_139605.1 55821163 3164391 complement(1013948..1014265) 1 NC_006448.1 truncated; acetyltransferase 1014265 3164391 stu1152 Streptococcus thermophilus LMG 18311 acetyltransferase YP_139605.1 1013948 R 264199 CDS YP_139606.1 55821164 3164058 complement(1014579..1014716) 1 NC_006448.1 truncated; acetyltransferase, truncated 1014716 3164058 stu1153 Streptococcus thermophilus LMG 18311 acetyltransferase, truncated YP_139606.1 1014579 R 264199 CDS YP_139607.1 55821165 3164358 1015036..1015845 1 NC_006448.1 hypothetical protein 1015845 3164358 stu1154 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139607.1 1015036 D 264199 CDS YP_139608.1 55821166 3164393 1015847..1017061 1 NC_006448.1 peptidoglycan branched peptide synthesis protein 1017061 murM 3164393 murM Streptococcus thermophilus LMG 18311 peptidoglycan branched peptide synthesis protein YP_139608.1 1015847 D 264199 CDS YP_139609.1 55821167 3164395 complement(1017533..1018363) 1 NC_006448.1 hypothetical protein 1018363 vicX 3164395 vicX Streptococcus thermophilus LMG 18311 hypothetical protein YP_139609.1 1017533 R 264199 CDS YP_139610.1 55821168 3163891 complement(1018351..1019691) 1 NC_006448.1 sensor histidine kinase 1019691 hk05 3163891 hk05 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139610.1 1018351 R 264199 CDS YP_139611.1 55821169 3164592 complement(1019684..1020391) 1 NC_006448.1 response regulator 1020391 rr05 3164592 rr05 Streptococcus thermophilus LMG 18311 response regulator YP_139611.1 1019684 R 264199 CDS YP_139612.1 55821170 3164396 1020918..1021685 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 1021685 3164396 stu1161 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_139612.1 1020918 D 264199 CDS YP_139613.1 55821171 3164500 1021697..1022530 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1022530 3164500 stu1162 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139613.1 1021697 D 264199 CDS YP_139614.1 55821172 3163851 1022548..1023246 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 1023246 3163851 stu1163 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_139614.1 1022548 D 264199 CDS YP_139615.1 55821173 3164020 1023258..1023908 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 1023908 3164020 stu1164 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_139615.1 1023258 D 264199 CDS YP_139616.1 55821174 3164022 complement(1023979..1024860) 1 NC_006448.1 competence associated membrane nuclease 1024860 endA 3164022 endA Streptococcus thermophilus LMG 18311 competence associated membrane nuclease YP_139616.1 1023979 R 264199 CDS YP_139617.1 55821175 3164021 complement(1024922..1025110) 1 NC_006448.1 competence-associated protein 1025110 epuA 3164021 epuA Streptococcus thermophilus LMG 18311 competence-associated protein YP_139617.1 1024922 R 264199 CDS YP_139618.1 55821176 3164490 complement(1025112..1026398) 1 NC_006448.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1026398 murA 3164490 murA Streptococcus thermophilus LMG 18311 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_139618.1 1025112 R 264199 CDS YP_139619.1 55821177 3164974 complement(1026453..1026689) 1 NC_006448.1 hypothetical protein 1026689 3164974 stu1168 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139619.1 1026453 R 264199 CDS YP_139620.1 55821178 3163774 complement(1026877..1027890) 1 NC_006448.1 UDP-glucose 4-epimerase 1027890 galE2 3163774 galE2 Streptococcus thermophilus LMG 18311 UDP-glucose 4-epimerase YP_139620.1 1026877 R 264199 CDS YP_139621.1 55821179 3163929 complement(1027905..1028108) 1 NC_006448.1 truncated; hypothetical protein 1028108 3163929 stu1170 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139621.1 1027905 R 264199 CDS YP_139622.1 55821180 3164361 complement(1028124..1028360) 1 NC_006448.1 truncated; hypothetical protein 1028360 3164361 stu1171 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139622.1 1028124 R 264199 CDS YP_139623.2 161611286 3164346 complement(1029362..1030555) 1 NC_006448.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1030555 metK 3164346 metK Streptococcus thermophilus LMG 18311 S-adenosylmethionine synthetase YP_139623.2 1029362 R 264199 CDS YP_139624.1 55821182 3164485 1030836..1031774 1 NC_006448.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1031774 birA 3164485 birA Streptococcus thermophilus LMG 18311 biotin--protein ligase YP_139624.1 1030836 D 264199 CDS YP_139625.1 55821183 3164471 complement(1032173..1033825) 1 NC_006448.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1033825 dnaX 3164471 dnaX Streptococcus thermophilus LMG 18311 DNA polymerase III subunits gamma and tau YP_139625.1 1032173 R 264199 CDS YP_139626.1 55821184 3164880 complement(1033825..1034334) 1 NC_006448.1 hypothetical protein 1034334 3164880 stu1175 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139626.1 1033825 R 264199 CDS YP_139627.1 55821186 3164863 complement(1034370..1035359) 1 NC_006448.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1035359 miaA 3164863 miaA Streptococcus thermophilus LMG 18311 tRNA delta(2)-isopentenylpyrophosphate transferase YP_139627.1 1034370 R 264199 CDS YP_139628.1 55821185 3165172 1035345..1035521 1 NC_006448.1 hypothetical protein 1035521 3165172 stu1176 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139628.1 1035345 D 264199 CDS YP_139629.1 55821187 3164708 1035574..1036113 1 NC_006448.1 hypothetical protein 1036113 3164708 stu1178 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139629.1 1035574 D 264199 CDS YP_139630.1 55821188 3165587 complement(1036465..1036812) 1 NC_006448.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1036812 rplS 3165587 rplS Streptococcus thermophilus LMG 18311 50S ribosomal protein L19 YP_139630.1 1036465 R 264199 CDS YP_139631.1 55821189 3163745 complement(1036940..1038166) 1 NC_006448.1 chloride channel (CIC) family protein 1038166 3163745 stu1180 Streptococcus thermophilus LMG 18311 chloride channel (CIC) family protein YP_139631.1 1036940 R 264199 CDS YP_139632.1 55821190 3164339 complement(1038176..1038448) 1 NC_006448.1 hypothetical protein 1038448 aroH 3164339 aroH Streptococcus thermophilus LMG 18311 hypothetical protein YP_139632.1 1038176 R 264199 CDS YP_139633.1 55821191 3164115 complement(1038523..1040058) 1 NC_006448.1 chloride channel 1040058 3164115 stu1182 Streptococcus thermophilus LMG 18311 chloride channel YP_139633.1 1038523 R 264199 CDS YP_139634.1 55821192 3163769 complement(1040109..1040477) 1 NC_006448.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1040477 fld 3163769 fld Streptococcus thermophilus LMG 18311 flavodoxin YP_139634.1 1040109 R 264199 CDS YP_139635.1 55821193 3164941 complement(1040737..1041009) 1 NC_006448.1 hypothetical protein 1041009 3164941 stu1184 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139635.1 1040737 R 264199 CDS YP_139636.1 55821194 3164944 complement(1041021..1041740) 1 NC_006448.1 proteinase 1041740 3164944 stu1185 Streptococcus thermophilus LMG 18311 proteinase YP_139636.1 1041021 R 264199 CDS YP_139637.1 55821195 3164947 complement(1041860..1042642) 1 NC_006448.1 esterase 1042642 estA 3164947 estA Streptococcus thermophilus LMG 18311 esterase YP_139637.1 1041860 R 264199 CDS YP_139638.1 55821196 3164635 complement(1042767..1044428) 1 NC_006448.1 metallo-beta-lactamase superfamily protein 1044428 3164635 stu1187 Streptococcus thermophilus LMG 18311 metallo-beta-lactamase superfamily protein YP_139638.1 1042767 R 264199 CDS YP_139639.1 55821197 3165110 complement(1044609..1045367) 1 NC_006448.1 ABC transporter ATP binding protein 1045367 3165110 stu1188 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_139639.1 1044609 R 264199 CDS YP_139640.1 55821198 3165538 complement(1045364..1046233) 1 NC_006448.1 ABC transporter membrane-spanning protein 1046233 3165538 stu1189 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_139640.1 1045364 R 264199 CDS YP_139641.1 55821199 3164948 complement(1046243..1047244) 1 NC_006448.1 ABC transporter substrate binding protein 1047244 3164948 stu1190 Streptococcus thermophilus LMG 18311 ABC transporter substrate binding protein YP_139641.1 1046243 R 264199 CDS YP_139642.1 55821200 3164949 complement(1047381..1047602) 1 NC_006448.1 hypothetical protein 1047602 3164949 stu1191 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139642.1 1047381 R 264199 CDS YP_139643.1 55821201 3164569 complement(1047804..1048052) 1 NC_006448.1 hypothetical protein 1048052 3164569 stu1192 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139643.1 1047804 R 264199 CDS YP_139644.1 55821202 3164546 complement(1048015..1048494) 1 NC_006448.1 truncated; surface-associated protein cshA precursor, truncated 1048494 3164546 stu1193 Streptococcus thermophilus LMG 18311 surface-associated protein cshA precursor, truncated YP_139644.1 1048015 R 264199 CDS YP_139645.1 55821203 3164670 complement(1048589..1048855) 1 NC_006448.1 hypothetical protein 1048855 3164670 stu1194 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139645.1 1048589 R 264199 CDS YP_139646.1 55821204 3164568 complement(1049017..1049256) 1 NC_006448.1 hypothetical protein 1049256 3164568 stu1195 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139646.1 1049017 R 264199 CDS YP_139647.2 161611285 3164178 complement(1050148..1051650) 1 NC_006448.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1051650 pyk 3164178 pyk Streptococcus thermophilus LMG 18311 pyruvate kinase YP_139647.2 1050148 R 264199 CDS YP_139648.1 55821206 3165272 complement(1051720..1052787) 1 NC_006448.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1052787 pfkA 3165272 pfkA Streptococcus thermophilus LMG 18311 6-phosphofructokinase YP_139648.1 1051720 R 264199 CDS YP_139649.1 55821207 3165009 complement(1052832..1055942) 1 NC_006448.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 1055942 dnaE 3165009 dnaE Streptococcus thermophilus LMG 18311 DNA polymerase III DnaE YP_139649.1 1052832 R 264199 CDS YP_139650.1 55821208 3163898 complement(1056095..1056880) 1 NC_006448.1 hypothetical protein 1056880 3163898 stu1199 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139650.1 1056095 R 264199 CDS YP_139651.1 55821209 3163871 complement(1056977..1057567) 1 NC_006448.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1057567 leuD 3163871 leuD Streptococcus thermophilus LMG 18311 isopropylmalate isomerase small subunit YP_139651.1 1056977 R 264199 CDS YP_139652.1 55821210 3165608 complement(1057577..1058971) 1 NC_006448.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1058971 leuC 3165608 leuC Streptococcus thermophilus LMG 18311 isopropylmalate isomerase large subunit YP_139652.1 1057577 R 264199 CDS YP_139653.1 55821211 3163992 complement(1059276..1060322) 1 NC_006448.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1060322 leuB 3163992 leuB Streptococcus thermophilus LMG 18311 3-isopropylmalate dehydrogenase YP_139653.1 1059276 R 264199 CDS YP_139654.1 55821212 3165609 complement(1060326..1061936) 1 NC_006448.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1061936 leuA 3165609 leuA Streptococcus thermophilus LMG 18311 2-isopropylmalate synthase YP_139654.1 1060326 R 264199 CDS YP_139655.1 55821213 3165581 complement(1062235..1062927) 1 NC_006448.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1062927 gpmA 3165581 gpmA Streptococcus thermophilus LMG 18311 phosphoglyceromutase YP_139655.1 1062235 R 264199 CDS YP_139656.1 55821214 3165549 1063138..1064121 1 NC_006448.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1064121 pyrDa 3165549 pyrDa Streptococcus thermophilus LMG 18311 dihydroorotate dehydrogenase 1A YP_139656.1 1063138 D 264199 CDS YP_139657.1 55821215 3165086 complement(1064186..1064353) 1 NC_006448.1 hypothetical protein 1064353 3165086 stu1208 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139657.1 1064186 R 264199 CDS YP_139658.1 55821216 3164882 complement(1064445..1064720) 1 NC_006448.1 histone-like DNA-binding protein 1064720 hstH 3164882 hstH Streptococcus thermophilus LMG 18311 histone-like DNA-binding protein YP_139658.1 1064445 R 264199 CDS YP_139659.1 55821217 3165360 complement(1064857..1065426) 1 NC_006448.1 hypothetical protein 1065426 3165360 stu1210 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139659.1 1064857 R 264199 CDS YP_139660.1 55821218 3163928 complement(1065419..1066225) 1 NC_006448.1 hypothetical protein 1066225 3163928 stu1211 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139660.1 1065419 R 264199 CDS YP_139661.1 55821219 3165557 complement(1066287..1067123) 1 NC_006448.1 hypothetical protein 1067123 3165557 stu1212 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139661.1 1066287 R 264199 CDS YP_139662.1 55821220 3163749 complement(1067194..1068864) 1 NC_006448.1 DNA repair and genetic recombination protein 1068864 recN 3163749 recN Streptococcus thermophilus LMG 18311 DNA repair and genetic recombination protein YP_139662.1 1067194 R 264199 CDS YP_139663.1 55821221 3163950 complement(1068873..1069319) 1 NC_006448.1 transcriptional repressor protein 1069319 3163950 stu1214 Streptococcus thermophilus LMG 18311 transcriptional repressor protein YP_139663.1 1068873 R 264199 CDS YP_139664.1 55821222 3163919 complement(1069267..1070133) 1 NC_006448.1 hemolysin 1070133 3163919 stu1215 Streptococcus thermophilus LMG 18311 hemolysin YP_139664.1 1069267 R 264199 CDS YP_139665.1 55821223 3164266 complement(1070126..1070998) 1 NC_006448.1 geranyltranstransferase, farnesyl diphosphate synthase 1070998 ispA 3164266 ispA Streptococcus thermophilus LMG 18311 geranyltranstransferase, farnesyl diphosphate synthase YP_139665.1 1070126 R 264199 CDS YP_139666.1 55821224 3163765 complement(1070998..1071213) 1 NC_006448.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1071213 xseB 3163765 xseB Streptococcus thermophilus LMG 18311 exodeoxyribonuclease VII small subunit YP_139666.1 1070998 R 264199 CDS YP_139667.1 55821225 3163938 complement(1071191..1072531) 1 NC_006448.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1072531 xseA 3163938 xseA Streptococcus thermophilus LMG 18311 exodeoxyribonuclease VII large subunit YP_139667.1 1071191 R 264199 CDS YP_139668.1 55821226 3164403 complement(1072720..1072965) 1 NC_006448.1 hypothetical protein 1072965 3164403 stu1219 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139668.1 1072720 R 264199 CDS YP_139669.1 55821227 3164612 complement(1073598..1074257) 1 NC_006448.1 endonuclease III, DNA repair 1074257 nth 3164612 nth Streptococcus thermophilus LMG 18311 endonuclease III, DNA repair YP_139669.1 1073598 R 264199 CDS YP_139670.1 55821228 3164127 complement(1074242..1074940) 1 NC_006448.1 DNA replication protein dnaD 1074940 dnaD 3164127 dnaD Streptococcus thermophilus LMG 18311 DNA replication protein dnaD YP_139670.1 1074242 R 264199 CDS YP_139671.1 55821229 3164611 complement(1075012..1075956) 1 NC_006448.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1075956 metA 3164611 metA Streptococcus thermophilus LMG 18311 homoserine O-succinyltransferase YP_139671.1 1075012 R 264199 CDS YP_139672.1 55821230 3165623 complement(1076127..1076645) 1 NC_006448.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1076645 apt 3165623 apt Streptococcus thermophilus LMG 18311 adenine phosphoribosyltransferase YP_139672.1 1076127 R 264199 CDS YP_139673.1 55821231 3164826 complement(1076760..1078970) 1 NC_006448.1 single strand DNA-specific exonuclease 1078970 recJ 3164826 recJ Streptococcus thermophilus LMG 18311 single strand DNA-specific exonuclease YP_139673.1 1076760 R 264199 CDS YP_139674.1 55821232 3163976 complement(1078983..1079750) 1 NC_006448.1 short chain dehydrogenase/reductase family oxidoreductase 1079750 3163976 stu1225 Streptococcus thermophilus LMG 18311 short chain dehydrogenase/reductase family oxidoreductase YP_139674.1 1078983 R 264199 CDS YP_139675.1 55821233 3164737 complement(1079750..1080679) 1 NC_006448.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1080679 elaC 3164737 elaC Streptococcus thermophilus LMG 18311 ribonuclease Z YP_139675.1 1079750 R 264199 CDS YP_139676.1 55821234 3165022 complement(1080710..1081351) 1 NC_006448.1 hypothetical protein 1081351 3165022 stu1227 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139676.1 1080710 R 264199 CDS YP_139677.1 55821235 3164884 complement(1081344..1082582) 1 NC_006448.1 GTP-binding protein 1082582 hflX 3164884 hflX Streptococcus thermophilus LMG 18311 GTP-binding protein YP_139677.1 1081344 R 264199 CDS YP_139678.1 55821236 3164336 complement(1082702..1084156) 1 NC_006448.1 cell division protein 1084156 rodA 3164336 rodA Streptococcus thermophilus LMG 18311 cell division protein YP_139678.1 1082702 R 264199 CDS YP_139679.1 55821237 3164210 complement(1084306..1084845) 1 NC_006448.1 hypothetical protein 1084845 3164210 stu1230 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139679.1 1084306 R 264199 CDS YP_139680.1 55821238 3163930 complement(1084942..1085148) 1 NC_006448.1 hypothetical protein 1085148 3163930 stu1231 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139680.1 1084942 R 264199 CDS YP_139681.1 55821239 3164149 complement(1085245..1085988) 1 NC_006448.1 hypothetical protein 1085988 hisK 3164149 hisK Streptococcus thermophilus LMG 18311 hypothetical protein YP_139681.1 1085245 R 264199 CDS YP_139682.1 55821240 3165040 complement(1085988..1086635) 1 NC_006448.1 hypothetical protein 1086635 3165040 stu1233 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139682.1 1085988 R 264199 CDS YP_139683.1 55821241 3165339 complement(1086622..1087395) 1 NC_006448.1 N-acetyl-glucosamine catabolism protein 1087395 3165339 stu1234 Streptococcus thermophilus LMG 18311 N-acetyl-glucosamine catabolism protein YP_139683.1 1086622 R 264199 CDS YP_139684.1 55821242 3164287 complement(1087397..1088140) 1 NC_006448.1 acyl-ACP thioesterase 1088140 3164287 stu1235 Streptococcus thermophilus LMG 18311 acyl-ACP thioesterase YP_139684.1 1087397 R 264199 CDS YP_139685.1 55821243 3165324 complement(1088141..1089277) 1 NC_006448.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1089277 hemN 3165324 hemN Streptococcus thermophilus LMG 18311 coproporphyrinogen III oxidase YP_139685.1 1088141 R 264199 CDS YP_139686.1 55821244 3165552 complement(1089546..1089695) 1 NC_006448.1 hypothetical protein 1089695 3165552 stu1237 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139686.1 1089546 R 264199 CDS YP_139687.1 55821245 3165417 1089875..1090129 1 NC_006448.1 hypothetical protein 1090129 3165417 stu1238 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139687.1 1089875 D 264199 CDS YP_139688.1 55821246 3165411 complement(1090244..1090573) 1 NC_006448.1 hypothetical protein 1090573 3165411 stu1239 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139688.1 1090244 R 264199 CDS YP_139689.1 55821247 3165385 complement(1090752..1091012) 1 NC_006448.1 hypothetical protein 1091012 3165385 stu1240 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139689.1 1090752 R 264199 CDS YP_139690.1 55821248 3165589 complement(1091033..1091245) 1 NC_006448.1 hypothetical protein 1091245 3165589 stu1241 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139690.1 1091033 R 264199 CDS YP_139691.1 55821249 3163751 complement(1091408..1092454) 1 NC_006448.1 dTDP-glucose-4,6-dehydratase 1092454 rmlB 3163751 rmlB Streptococcus thermophilus LMG 18311 dTDP-glucose-4,6-dehydratase YP_139691.1 1091408 R 264199 CDS YP_139692.1 55821250 3165338 complement(1092884..1093477) 1 NC_006448.1 dTDP-4-keto-L-rhamnose reductase 1093477 rmlC 3165338 rmlC Streptococcus thermophilus LMG 18311 dTDP-4-keto-L-rhamnose reductase YP_139692.1 1092884 R 264199 CDS YP_139693.1 55821251 3165501 complement(1093477..1094346) 1 NC_006448.1 glucose-1-phosphate thymidyl transferase 1094346 rmlA 3165501 rmlA Streptococcus thermophilus LMG 18311 glucose-1-phosphate thymidyl transferase YP_139693.1 1093477 R 264199 CDS YP_139694.1 55821252 3165437 complement(1094578..1095681) 1 NC_006448.1 oxidoreductase, DadA family protein/D-amino acid oxidase 1095681 3165437 stu1245 Streptococcus thermophilus LMG 18311 oxidoreductase, DadA family protein/D-amino acid oxidase YP_139694.1 1094578 R 264199 CDS YP_139695.1 55821253 3165465 complement(1095736..1096056) 1 NC_006448.1 truncated; hypothetical protein 1096056 3165465 stu1246 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139695.1 1095736 R 264199 CDS YP_139696.1 55821254 3165440 complement(1095827..1096369) 1 NC_006448.1 truncated; hypothetical protein 1096369 3165440 stu1247 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139696.1 1095827 R 264199 CDS YP_139697.1 55821255 3165160 complement(1096578..1097366) 1 NC_006448.1 hypothetical protein 1097366 3165160 stu1248 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139697.1 1096578 R 264199 CDS YP_139698.1 55821256 3165344 complement(1097356..1098042) 1 NC_006448.1 hypothetical protein 1098042 3165344 stu1249 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139698.1 1097356 R 264199 CDS YP_139699.1 55821257 3165261 complement(1098140..1098580) 1 NC_006448.1 hypothetical protein 1098580 3165261 stu1250 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139699.1 1098140 R 264199 CDS YP_139700.1 55821258 3165474 complement(1098583..1099935) 1 NC_006448.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1099935 glmM 3165474 glmM Streptococcus thermophilus LMG 18311 phosphoglucosamine mutase YP_139700.1 1098583 R 264199 CDS YP_139701.1 55821259 3164281 complement(1100159..1101124) 1 NC_006448.1 hypothetical protein 1101124 3164281 stu1252 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139701.1 1100159 R 264199 CDS YP_139702.1 55821260 3165409 complement(1101121..1101978) 1 NC_006448.1 hypothetical protein 1101978 3165409 stu1253 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139702.1 1101121 R 264199 CDS YP_139703.1 55821261 3165407 1102074..1103417 1 NC_006448.1 Mur ligase family protein 1103417 3165407 stu1254 Streptococcus thermophilus LMG 18311 Mur ligase family protein YP_139703.1 1102074 D 264199 CDS YP_139704.1 55821262 3165060 1103417..1104205 1 NC_006448.1 cobyric acid synthase 1104205 cobQ 3165060 cobQ Streptococcus thermophilus LMG 18311 cobyric acid synthase YP_139704.1 1103417 D 264199 CDS YP_139705.1 55821263 3165354 complement(1104256..1106811) 1 NC_006448.1 hypothetical protein 1106811 3165354 stu1256 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139705.1 1104256 R 264199 CDS YP_139706.1 55821264 3165460 complement(1106808..1107527) 1 NC_006448.1 hypothetical protein 1107527 3165460 stu1257 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139706.1 1106808 R 264199 CDS YP_139707.1 55821265 3165353 complement(1108053..1109972) 1 NC_006448.1 ABC transporter ATP-binding protein 1109972 3165353 stu1259 Streptococcus thermophilus LMG 18311 ABC transporter ATP-binding protein YP_139707.1 1108053 R 264199 CDS YP_139708.1 55821266 3165480 complement(1110009..1110644) 1 NC_006448.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1110644 udk 3165480 udk Streptococcus thermophilus LMG 18311 uridine kinase YP_139708.1 1110009 R 264199 CDS YP_139709.1 55821267 3163825 1110742..1111824 1 NC_006448.1 ATP-dependent RNA helicase 1111824 deaD 3163825 deaD Streptococcus thermophilus LMG 18311 ATP-dependent RNA helicase YP_139709.1 1110742 D 264199 CDS YP_139710.1 55821268 3164276 complement(1112113..1113546) 1 NC_006448.1 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1113546 gapN 3164276 gapN Streptococcus thermophilus LMG 18311 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase YP_139710.1 1112113 R 264199 CDS YP_139711.1 55821269 3165255 complement(1113764..1115497) 1 NC_006448.1 phosphoenolpyruvate:sugar phosphotransferase system enzyme I 1115497 ptsI 3165255 ptsI Streptococcus thermophilus LMG 18311 phosphoenolpyruvate:sugar phosphotransferase system enzyme I YP_139711.1 1113764 R 264199 CDS YP_139712.1 55821270 3165442 complement(1115502..1115765) 1 NC_006448.1 phosphocarrier protein HPr 1115765 ptsH 3165442 ptsH Streptococcus thermophilus LMG 18311 phosphocarrier protein HPr YP_139712.1 1115502 R 264199 CDS YP_139713.1 55821271 3165469 complement(1116027..1117202) 1 NC_006448.1 isocitrate dehydrogenase 1117202 icd 3165469 icd Streptococcus thermophilus LMG 18311 isocitrate dehydrogenase YP_139713.1 1116027 R 264199 CDS YP_139714.1 55821272 3165431 complement(1117217..1118341) 1 NC_006448.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 1118341 gltA 3165431 gltA Streptococcus thermophilus LMG 18311 citrate synthase YP_139714.1 1117217 R 264199 CDS YP_139715.1 55821273 3165389 complement(1118343..1121006) 1 NC_006448.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1121006 citB 3165389 citB Streptococcus thermophilus LMG 18311 aconitate hydratase YP_139715.1 1118343 R 264199 CDS YP_139716.1 55821274 3165309 1121337..1121561 1 NC_006448.1 glutaredoxin 1121561 nrdH 3165309 nrdH Streptococcus thermophilus LMG 18311 glutaredoxin YP_139716.1 1121337 D 264199 CDS YP_139717.1 55821275 3165252 1121648..1123807 1 NC_006448.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1123807 nrdE 3165252 nrdE Streptococcus thermophilus LMG 18311 ribonucleotide-diphosphate reductase subunit alpha YP_139717.1 1121648 D 264199 CDS YP_139718.1 55821276 3165510 1123966..1124928 1 NC_006448.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1124928 nrdF 3165510 nrdF Streptococcus thermophilus LMG 18311 ribonucleotide-diphosphate reductase subunit beta YP_139718.1 1123966 D 264199 CDS YP_139719.1 55821277 3165364 1125244..1125450 1 NC_006448.1 truncated; truncated IS1193 transposase 1125450 3165364 stu1272 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139719.1 1125244 D 264199 CDS YP_139720.1 55821278 3165551 1125594..1126019 1 NC_006448.1 truncated; hypothetical protein 1126019 3165551 stu1273 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139720.1 1125594 D 264199 CDS YP_139721.1 55821279 3165346 1126073..1126459 1 NC_006448.1 truncated; hypothetical protein 1126459 3165346 stu1274 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139721.1 1126073 D 264199 CDS YP_139722.1 55821280 3165421 complement(1126724..1127692) 1 NC_006448.1 hypothetical protein 1127692 3165421 stu1275 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139722.1 1126724 R 264199 CDS YP_139723.1 55821281 3165302 complement(1127889..1128218) 1 NC_006448.1 hypothetical protein 1128218 3165302 stu1276 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139723.1 1127889 R 264199 CDS YP_139724.1 55821282 3165297 complement(1128243..1128620) 1 NC_006448.1 truncated; sortase, truncated 1128620 3165297 stu1277 Streptococcus thermophilus LMG 18311 sortase, truncated YP_139724.1 1128243 R 264199 CDS YP_139725.1 55821283 3165066 complement(1128633..1129004) 1 NC_006448.1 truncated; sortase, truncated 1129004 3165066 stu1278 Streptococcus thermophilus LMG 18311 sortase, truncated YP_139725.1 1128633 R 264199 CDS YP_139726.1 55821284 3165299 complement(1129037..1131472) 1 NC_006448.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1131472 gyrA 3165299 gyrA Streptococcus thermophilus LMG 18311 DNA gyrase subunit A YP_139726.1 1129037 R 264199 CDS YP_139727.1 55821285 3165511 1131691..1132677 1 NC_006448.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1132677 ldh 3165511 ldh Streptococcus thermophilus LMG 18311 L-lactate dehydrogenase YP_139727.1 1131691 D 264199 CDS YP_139728.1 55821286 3165373 complement(1132770..1134155) 1 NC_006448.1 NADH oxidase (H2O-forming) 1134155 nox 3165373 nox Streptococcus thermophilus LMG 18311 NADH oxidase (H2O-forming) YP_139728.1 1132770 R 264199 CDS YP_139729.1 55821287 3165289 complement(1134459..1135997) 1 NC_006448.1 ABC transporter ATP-binding protein 1135997 3165289 stu1282 Streptococcus thermophilus LMG 18311 ABC transporter ATP-binding protein YP_139729.1 1134459 R 264199 CDS YP_139730.1 55821288 3165321 complement(1136068..1136559) 1 NC_006448.1 hypothetical protein 1136559 3165321 stu1283 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139730.1 1136068 R 264199 CDS YP_139731.1 55821289 3165384 complement(1136696..1137517) 1 NC_006448.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1137517 pdxK 3165384 pdxK Streptococcus thermophilus LMG 18311 pyridoxamine kinase YP_139731.1 1136696 R 264199 CDS YP_139732.1 55821290 3165582 complement(1137518..1138027) 1 NC_006448.1 hypothetical protein 1138027 3165582 stu1285 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139732.1 1137518 R 264199 CDS YP_139733.1 55821291 3165356 complement(1138165..1138695) 1 NC_006448.1 hypothetical protein 1138695 3165356 stu1286 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139733.1 1138165 R 264199 CDS YP_139734.1 55821292 3165284 1138853..1139191 1 NC_006448.1 truncated; transcriptional regulator, truncated 1139191 3165284 stu1287 Streptococcus thermophilus LMG 18311 transcriptional regulator, truncated YP_139734.1 1138853 D 264199 CDS YP_139735.1 55821293 3164698 1139318..1140118 1 NC_006448.1 truncated; transcriptional regulator, truncated 1140118 3164698 stu1288 Streptococcus thermophilus LMG 18311 transcriptional regulator, truncated YP_139735.1 1139318 D 264199 CDS YP_139736.1 55821294 3164175 complement(1140162..1140500) 1 NC_006448.1 hypothetical protein 1140500 3164175 stu1289 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139736.1 1140162 R 264199 CDS YP_139737.1 55821295 3165307 complement(1140591..1140896) 1 NC_006448.1 hypothetical protein 1140896 3165307 stu1290 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139737.1 1140591 R 264199 CDS YP_139738.1 55821296 3165416 complement(1141232..1143682) 1 NC_006448.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1143682 pheT 3165416 pheT Streptococcus thermophilus LMG 18311 phenylalanyl-tRNA synthetase subunit beta YP_139738.1 1141232 R 264199 CDS YP_139739.1 55821297 3165316 complement(1143941..1144459) 1 NC_006448.1 transcriptional regulator 1144459 3165316 stu1293 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_139739.1 1143941 R 264199 CDS YP_139740.2 161611284 3164424 complement(1144476..1145519) 1 NC_006448.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1145519 pheS 3164424 pheS Streptococcus thermophilus LMG 18311 phenylalanyl-tRNA synthetase subunit alpha YP_139740.2 1144476 R 264199 CDS YP_139741.1 55821299 3165314 complement(1146139..1149672) 1 NC_006448.1 chromosome segregation SMC protein 1149672 smc 3165314 smc Streptococcus thermophilus LMG 18311 chromosome segregation SMC protein YP_139741.1 1146139 R 264199 CDS YP_139742.1 55821300 3165326 complement(1149675..1150388) 1 NC_006448.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1150388 rnc 3165326 rnc Streptococcus thermophilus LMG 18311 ribonuclease III YP_139742.1 1149675 R 264199 CDS YP_139743.1 55821301 3165374 complement(1150519..1151490) 1 NC_006448.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1151490 dapA 3165374 dapA Streptococcus thermophilus LMG 18311 dihydrodipicolinate synthase YP_139743.1 1150519 R 264199 CDS YP_139744.1 55821302 3165288 complement(1151792..1152868) 1 NC_006448.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1152868 asd 3165288 asd Streptococcus thermophilus LMG 18311 aspartate-semialdehyde dehydrogenase YP_139744.1 1151792 R 264199 CDS YP_139745.1 55821303 3165461 complement(1153158..1153637) 1 NC_006448.1 DNA alkylation repair protein 1153637 alkD 3165461 alkD Streptococcus thermophilus LMG 18311 DNA alkylation repair protein YP_139745.1 1153158 R 264199 CDS YP_139746.1 55821304 3165503 complement(1153999..1154580) 1 NC_006448.1 phosphinothricin acetyltransferase 1154580 3165503 stu1301 Streptococcus thermophilus LMG 18311 phosphinothricin acetyltransferase YP_139746.1 1153999 R 264199 CDS YP_139747.1 55821305 3165375 1154804..1155010 1 NC_006448.1 truncated; truncated IS1193 transposase 1155010 3165375 stu1302 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139747.1 1154804 D 264199 CDS YP_139748.1 55821306 3165542 1155128..1155364 1 NC_006448.1 truncated; truncated IS1193 transposase 1155364 3165542 stu1303 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139748.1 1155128 D 264199 CDS YP_139749.1 55821307 3165056 1155357..1155524 1 NC_006448.1 truncated; truncated IS1193 transposase 1155524 3165056 stu1304 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139749.1 1155357 D 264199 CDS YP_139750.1 55821308 3165359 complement(1155563..1157014) 1 NC_006448.1 cardiolipin synthetase 1157014 cls 3165359 cls Streptococcus thermophilus LMG 18311 cardiolipin synthetase YP_139750.1 1155563 R 264199 CDS YP_139751.1 55821309 3165332 complement(1157202..1158989) 1 NC_006448.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1158989 uvrC 3165332 uvrC Streptococcus thermophilus LMG 18311 excinuclease ABC subunit C YP_139751.1 1157202 R 264199 CDS YP_139752.1 55821310 3163758 complement(1159049..1159744) 1 NC_006448.1 HAD superfamily hydrolase 1159744 3163758 stu1307 Streptococcus thermophilus LMG 18311 HAD superfamily hydrolase YP_139752.1 1159049 R 264199 CDS YP_139753.1 55821311 3165371 1160071..1160505 1 NC_006448.1 biotin synthase 1160505 bioY2 3165371 bioY2 Streptococcus thermophilus LMG 18311 biotin synthase YP_139753.1 1160071 D 264199 CDS YP_139754.1 55821312 3165573 complement(1160740..1161429) 1 NC_006448.1 choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein 1161429 proWX 3165573 proWX Streptococcus thermophilus LMG 18311 choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein YP_139754.1 1160740 R 264199 CDS YP_139755.1 55821313 3165518 complement(1161371..1162126) 1 NC_006448.1 choline/proline/glycine betaine ABC uptake transporter ATP-binding protein 1162126 proV 3165518 proV Streptococcus thermophilus LMG 18311 choline/proline/glycine betaine ABC uptake transporter ATP-binding protein YP_139755.1 1161371 R 264199 CDS YP_139756.1 55821314 3165313 complement(1162138..1163055) 1 NC_006448.1 choline/proline/glycine betaine ABC uptake transporter substrate binding protein 1163055 proWY 3165313 proWY Streptococcus thermophilus LMG 18311 choline/proline/glycine betaine ABC uptake transporter substrate binding protein YP_139756.1 1162138 R 264199 CDS YP_139757.1 55821315 3164264 complement(1163052..1163711) 1 NC_006448.1 choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein 1163711 proWZ 3164264 proWZ Streptococcus thermophilus LMG 18311 choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein YP_139757.1 1163052 R 264199 CDS YP_139758.1 55821316 3165430 complement(1163768..1165264) 1 NC_006448.1 histidine ammonia-lyase 1165264 hutH 3165430 hutH Streptococcus thermophilus LMG 18311 histidine ammonia-lyase YP_139758.1 1163768 R 264199 CDS YP_139759.1 55821317 3164263 complement(1165287..1166390) 1 NC_006448.1 hypothetical protein 1166390 3164263 stu1314 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139759.1 1165287 R 264199 CDS YP_139760.1 55821318 3165487 complement(1166407..1168041) 1 NC_006448.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1168041 hutU 3165487 hutU Streptococcus thermophilus LMG 18311 urocanate hydratase YP_139760.1 1166407 R 264199 CDS YP_139761.1 55821319 3165526 1168480..1169193 1 NC_006448.1 L-serine dehydratase subunit beta 1169193 sdaB 3165526 sdaB Streptococcus thermophilus LMG 18311 L-serine dehydratase subunit beta YP_139761.1 1168480 D 264199 CDS YP_139762.1 55821320 3164026 1169206..1170075 1 NC_006448.1 L-serine dehydratase subunit alpha 1170075 sdaA 3164026 sdaA Streptococcus thermophilus LMG 18311 L-serine dehydratase subunit alpha YP_139762.1 1169206 D 264199 CDS YP_139763.1 55821321 3165287 complement(1170798..1171367) 1 NC_006448.1 hypothetical protein 1171367 3165287 stu1318 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139763.1 1170798 R 264199 CDS YP_139764.1 55821322 3164262 complement(1171503..1172294) 1 NC_006448.1 hypothetical protein 1172294 3164262 stu1319 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139764.1 1171503 R 264199 CDS YP_139765.1 55821323 3165327 complement(1172291..1172572) 1 NC_006448.1 truncated; hypothetical protein 1172572 3165327 stu1320 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139765.1 1172291 R 264199 CDS YP_139766.1 55821324 3165453 complement(1172542..1173114) 1 NC_006448.1 truncated; hypothetical protein 1173114 3165453 stu1321 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139766.1 1172542 R 264199 CDS YP_139767.1 55821325 3165310 complement(1173300..1173518) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1173518 3165310 stu1322 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_139767.1 1173300 R 264199 CDS YP_139768.1 55821326 3165280 complement(1173496..1173663) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1173663 3165280 stu1323 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_139768.1 1173496 R 264199 CDS YP_139769.1 55821327 3165471 complement(1173679..1173933) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1173933 3165471 stu1324 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_139769.1 1173679 R 264199 CDS YP_139770.1 55821328 3164256 complement(1174475..1175077) 1 NC_006448.1 response regulator 1175077 rr06 3164256 rr06 Streptococcus thermophilus LMG 18311 response regulator YP_139770.1 1174475 R 264199 CDS YP_139771.1 55821329 3165450 complement(1175074..1176174) 1 NC_006448.1 sensor histidine kinase 1176174 hk06 3165450 hk06 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139771.1 1175074 R 264199 CDS YP_139772.1 55821330 3165336 complement(1176161..1176898) 1 NC_006448.1 ABC transporter membrane-spanning protein 1176898 3165336 stu1327 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_139772.1 1176161 R 264199 CDS YP_139773.1 55821331 3165516 complement(1176895..1177776) 1 NC_006448.1 ABC transporter ATP binding protein 1177776 3165516 stu1328 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_139773.1 1176895 R 264199 CDS YP_139774.1 55821332 3165475 complement(1177959..1178168) 1 NC_006448.1 hypothetical protein 1178168 3165475 stu1329 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139774.1 1177959 R 264199 CDS YP_139775.1 55821333 3165386 complement(1178320..1179258) 1 NC_006448.1 bile acid:Na+ symporter (BASS) family protein 1179258 3165386 stu1330 Streptococcus thermophilus LMG 18311 bile acid:Na+ symporter (BASS) family protein YP_139775.1 1178320 R 264199 CDS YP_139776.1 55821334 3165515 complement(1179404..1179853) 1 NC_006448.1 cytidine/deoxycytidylate deaminase family protein 1179853 3165515 stu1331 Streptococcus thermophilus LMG 18311 cytidine/deoxycytidylate deaminase family protein YP_139776.1 1179404 R 264199 CDS YP_139777.1 55821335 3165293 complement(1180021..1180242) 1 NC_006448.1 hypothetical protein 1180242 3165293 stu1332 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139777.1 1180021 R 264199 CDS YP_139778.1 55821336 3164248 complement(1180327..1182327) 1 NC_006448.1 peptide-4 ABC transporter substrate binding/membrane-spanning protein 1182327 3164248 stu1333 Streptococcus thermophilus LMG 18311 peptide-4 ABC transporter substrate binding/membrane-spanning protein YP_139778.1 1180327 R 264199 CDS YP_139779.1 55821337 3164416 complement(1182329..1183087) 1 NC_006448.1 peptide-4 ABC transporter ATP binding protein 1183087 3164416 stu1334 Streptococcus thermophilus LMG 18311 peptide-4 ABC transporter ATP binding protein YP_139779.1 1182329 R 264199 CDS YP_139780.1 55821338 3164775 complement(1183232..1184206) 1 NC_006448.1 sensor histidine kinase 1184206 hk07 3164775 hk07 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139780.1 1183232 R 264199 CDS YP_139781.1 55821339 3165400 complement(1184196..1184876) 1 NC_006448.1 response regulator 1184876 rr07 3165400 rr07 Streptococcus thermophilus LMG 18311 response regulator YP_139781.1 1184196 R 264199 CDS YP_139782.1 55821340 3163822 1185428..1185565 1 NC_006448.1 truncated; xanthine phosphoribosyltransferase, truncated 1185565 3163822 stu1337 Streptococcus thermophilus LMG 18311 xanthine phosphoribosyltransferase, truncated YP_139782.1 1185428 D 264199 CDS YP_139783.1 55821341 3165387 1185543..1185908 1 NC_006448.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1185908 3165387 stu1338 Streptococcus thermophilus LMG 18311 xanthine phosphoribosyltransferase YP_139783.1 1185543 D 264199 CDS YP_139784.1 55821342 3165322 1185997..1186467 1 NC_006448.1 truncated; hypothetical protein 1186467 3165322 stu1339 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139784.1 1185997 D 264199 CDS YP_139785.1 55821343 3165452 1186473..1187177 1 NC_006448.1 truncated; hypothetical protein 1187177 3165452 stu1340 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139785.1 1186473 D 264199 CDS YP_139786.1 55821344 3163913 1187305..1188654 1 NC_006448.1 MATE family drug:Na+ antiporter 1188654 norM 3163913 norM Streptococcus thermophilus LMG 18311 MATE family drug:Na+ antiporter YP_139786.1 1187305 D 264199 CDS YP_139787.1 55821345 3164136 complement(1189021..1190043) 1 NC_006448.1 this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 1190043 msrA1 3164136 msrA1 Streptococcus thermophilus LMG 18311 bifunctional methionine sulfoxide reductase A/B protein YP_139787.1 1189021 R 264199 CDS YP_139788.1 55821346 3165484 complement(1190123..1190992) 1 NC_006448.1 IS3 familytransposase orf2 1190992 tnpSth1 3165484 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf2 YP_139788.1 1190123 R 264199 CDS YP_139789.1 55821347 3165347 complement(1191007..1191747) 1 NC_006448.1 IS3 familytransposase orf1 1191747 tnpSth1 3165347 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf1 YP_139789.1 1191007 R 264199 CDS YP_139790.1 55821348 3164758 complement(1191786..1193114) 1 NC_006448.1 branched chain amino acid:Na+ symporter 1193114 brnQ 3164758 brnQ Streptococcus thermophilus LMG 18311 branched chain amino acid:Na+ symporter YP_139790.1 1191786 R 264199 CDS YP_139791.1 55821349 3165361 complement(1193328..1193714) 1 NC_006448.1 truncated; mannose-6-phosphate isomerase 1193714 3165361 stu1358 Streptococcus thermophilus LMG 18311 mannose-6-phosphate isomerase YP_139791.1 1193328 R 264199 CDS YP_139792.1 55821350 3165378 complement(1193689..1194027) 1 NC_006448.1 truncated; mannose-6-phosphate isomerase 1194027 3165378 stu1359 Streptococcus thermophilus LMG 18311 mannose-6-phosphate isomerase YP_139792.1 1193689 R 264199 CDS YP_139793.1 55821351 3164983 1194172..1194366 1 NC_006448.1 hypothetical protein 1194366 3164983 stu1360 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139793.1 1194172 D 264199 CDS YP_139794.1 55821352 3165277 complement(1195236..1196621) 1 NC_006448.1 amino acid transporter (AAT) family protein 1196621 3165277 stu1361 Streptococcus thermophilus LMG 18311 amino acid transporter (AAT) family protein YP_139794.1 1195236 R 264199 CDS YP_139795.1 55821353 3165294 complement(1197047..1197649) 1 NC_006448.1 hypothetical protein 1197649 3165294 stu1363 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139795.1 1197047 R 264199 CDS YP_139796.1 55821354 3165462 complement(1197829..1197954) 1 NC_006448.1 truncated; hypothetical protein 1197954 3165462 stu1364 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139796.1 1197829 R 264199 CDS YP_139797.1 55821355 3165337 complement(1198102..1198608) 1 NC_006448.1 truncated; hypothetical protein 1198608 3165337 stu1365 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139797.1 1198102 R 264199 CDS YP_139798.1 55821356 3165413 complement(1198776..1199225) 1 NC_006448.1 Rrf2 family protein 1199225 3165413 stu1366 Streptococcus thermophilus LMG 18311 Rrf2 family protein YP_139798.1 1198776 R 264199 CDS YP_139799.1 55821357 3165481 complement(1199407..1200270) 1 NC_006448.1 hypothetical protein 1200270 3165481 stu1367 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139799.1 1199407 R 264199 CDS YP_139800.1 55821358 3165383 complement(1200257..1201549) 1 NC_006448.1 cellobiose PTS system component IIC 1201549 celB 3165383 celB Streptococcus thermophilus LMG 18311 cellobiose PTS system component IIC YP_139800.1 1200257 R 264199 CDS YP_139801.1 55821359 3165271 complement(1201738..1202391) 1 NC_006448.1 NAD(P)H nitroreductase 1202391 3165271 stu1369 Streptococcus thermophilus LMG 18311 NAD(P)H nitroreductase YP_139801.1 1201738 R 264199 CDS YP_139802.1 55821360 3165590 complement(1202463..1203002) 1 NC_006448.1 hypothetical protein 1203002 3165590 stu1370 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139802.1 1202463 R 264199 CDS YP_139803.1 55821361 3165348 complement(1203210..1204112) 1 NC_006448.1 aldo/keto reductase 1204112 3165348 stu1371 Streptococcus thermophilus LMG 18311 aldo/keto reductase YP_139803.1 1203210 R 264199 CDS YP_139804.1 55821362 3164238 complement(1204185..1204742) 1 NC_006448.1 truncated; UDP-glucose 4-epimerase, truncated 1204742 3164238 stu1373 Streptococcus thermophilus LMG 18311 UDP-glucose 4-epimerase, truncated YP_139804.1 1204185 R 264199 CDS YP_139805.1 55821363 3165490 complement(1205092..1209504) 1 NC_006448.1 type II restriction-modification system restriction subunit 1209504 sthII 3165490 sthII Streptococcus thermophilus LMG 18311 type II restriction-modification system restriction subunit YP_139805.1 1205092 R 264199 CDS YP_139806.1 55821364 3164567 complement(1209511..1210185) 1 NC_006448.1 type II restriction-modification system modification subunit 1210185 llaBIIM 3164567 llaBIIM Streptococcus thermophilus LMG 18311 type II restriction-modification system modification subunit YP_139806.1 1209511 R 264199 CDS YP_139807.1 55821365 3165081 1210446..1211930 1 NC_006448.1 hypothetical protein 1211930 3165081 stu1377 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139807.1 1210446 D 264199 CDS YP_139808.1 55821366 3165365 complement(1212150..1212494) 1 NC_006448.1 hypothetical protein 1212494 3165365 stu1378 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139808.1 1212150 R 264199 CDS YP_139809.1 55821367 3165395 1212754..1213017 1 NC_006448.1 hypothetical protein 1213017 3165395 stu1379 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139809.1 1212754 D 264199 CDS YP_139810.1 55821368 3165392 complement(1213203..1213478) 1 NC_006448.1 truncated; response regulator, truncated 1213478 3165392 stu1380 Streptococcus thermophilus LMG 18311 response regulator, truncated YP_139810.1 1213203 R 264199 CDS YP_139811.1 55821369 3165535 complement(1213524..1213886) 1 NC_006448.1 truncated; response regulator, truncated 1213886 3165535 stu1381 Streptococcus thermophilus LMG 18311 response regulator, truncated YP_139811.1 1213524 R 264199 CDS YP_139812.1 55821370 3165533 complement(1213966..1214421) 1 NC_006448.1 cell wall surface anchor family protein 1214421 3165533 stu1382 Streptococcus thermophilus LMG 18311 cell wall surface anchor family protein YP_139812.1 1213966 R 264199 CDS YP_139813.1 55821371 3165342 1214459..1214677 1 NC_006448.1 hypothetical protein 1214677 3165342 stu1383 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139813.1 1214459 D 264199 CDS YP_139814.1 55821372 3165493 complement(1214723..1215082) 1 NC_006448.1 hypothetical protein 1215082 3165493 stu1384 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139814.1 1214723 R 264199 CDS YP_139815.1 55821373 3164915 complement(1215079..1216494) 1 NC_006448.1 SOS responce UmuC protein 1216494 umuC1 3164915 umuC1 Streptococcus thermophilus LMG 18311 SOS responce UmuC protein YP_139815.1 1215079 R 264199 CDS YP_139816.1 55821374 3165525 complement(1216667..1217704) 1 NC_006448.1 hypothetical protein 1217704 3165525 stu1386 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139816.1 1216667 R 264199 CDS YP_139817.1 55821375 3165415 1217942..1218229 1 NC_006448.1 hypothetical protein 1218229 3165415 stu1387 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139817.1 1217942 D 264199 CDS YP_139818.1 55821376 3165341 1218478..1218726 1 NC_006448.1 hypothetical protein 1218726 3165341 stu1388 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139818.1 1218478 D 264199 CDS YP_139819.1 55821377 3165278 1218937..1219554 1 NC_006448.1 resistance to homoserine/threonine (RhtB) family protein 1219554 3165278 stu1389 Streptococcus thermophilus LMG 18311 resistance to homoserine/threonine (RhtB) family protein YP_139819.1 1218937 D 264199 CDS YP_139820.1 55821378 3164233 1219840..1219932 1 NC_006448.1 truncated; truncated IS1193 transposase 1219932 3164233 stu1390 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139820.1 1219840 D 264199 CDS YP_139821.1 55821379 3165495 complement(1219895..1220254) 1 NC_006448.1 hypothetical protein 1220254 3165495 stu1391 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139821.1 1219895 R 264199 CDS YP_139822.1 55821380 3165317 complement(1220812..1222905) 1 NC_006448.1 glycosyl transferase 1222905 3165317 stu1392 Streptococcus thermophilus LMG 18311 glycosyl transferase YP_139822.1 1220812 R 264199 CDS YP_139823.1 55821381 3165300 1223484..1223819 1 NC_006448.1 hypothetical protein 1223819 3165300 stu1393 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139823.1 1223484 D 264199 CDS YP_139824.1 55821382 3165463 complement(1224240..1227419) 1 NC_006448.1 ATP-dependent dsDNA exonuclease 1227419 sbcC 3165463 sbcC Streptococcus thermophilus LMG 18311 ATP-dependent dsDNA exonuclease YP_139824.1 1224240 R 264199 CDS YP_139825.1 55821383 3165276 complement(1227416..1228642) 1 NC_006448.1 ATP-dependent dsDNA exonuclease 1228642 sbcD 3165276 sbcD Streptococcus thermophilus LMG 18311 ATP-dependent dsDNA exonuclease YP_139825.1 1227416 R 264199 CDS YP_139826.1 55821384 3164581 complement(1229478..1232558) 1 NC_006448.1 beta-galactosidase 1232558 lacZ 3164581 lacZ Streptococcus thermophilus LMG 18311 beta-galactosidase YP_139826.1 1229478 R 264199 CDS YP_139827.1 55821385 3165412 complement(1232562..1234466) 1 NC_006448.1 lactose permease 1234466 lacS 3165412 lacS Streptococcus thermophilus LMG 18311 lactose permease YP_139827.1 1232562 R 264199 CDS YP_139828.1 55821386 3165335 complement(1234569..1235615) 1 NC_006448.1 aldose 1-epimerase 1235615 galM 3165335 galM Streptococcus thermophilus LMG 18311 aldose 1-epimerase YP_139828.1 1234569 R 264199 CDS YP_139829.1 55821387 3165282 complement(1235685..1236686) 1 NC_006448.1 UDP-glucose 4-epimerase 1236686 galE1 3165282 galE1 Streptococcus thermophilus LMG 18311 UDP-glucose 4-epimerase YP_139829.1 1235685 R 264199 CDS YP_139830.1 55821388 3164795 complement(1236716..1238224) 1 NC_006448.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1238224 galT 3164795 galT Streptococcus thermophilus LMG 18311 galactose-1-phosphate uridylyltransferase YP_139830.1 1236716 R 264199 CDS YP_139831.1 55821389 3165328 complement(1238217..1239383) 1 NC_006448.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1239383 galK 3165328 galK Streptococcus thermophilus LMG 18311 galactokinase YP_139831.1 1238217 R 264199 CDS YP_139832.1 55821390 3164454 1239526..1240521 1 NC_006448.1 galactose operon repressor 1240521 galR 3164454 galR Streptococcus thermophilus LMG 18311 galactose operon repressor YP_139832.1 1239526 D 264199 CDS YP_139833.1 55821391 3164218 complement(1241316..1241504) 1 NC_006448.1 truncated; hypothetical protein 1241504 3164218 stu1405 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139833.1 1241316 R 264199 CDS YP_139834.1 55821392 3164230 complement(1241677..1242768) 1 NC_006448.1 truncated; zinc metalloprotease ZmpB, truncated 1242768 3164230 stu1406 Streptococcus thermophilus LMG 18311 zinc metalloprotease ZmpB, truncated YP_139834.1 1241677 R 264199 CDS YP_139835.1 55821393 3165304 complement(1242731..1243171) 1 NC_006448.1 truncated; zinc metalloprotease ZmpB, truncated 1243171 3165304 stu1407 Streptococcus thermophilus LMG 18311 zinc metalloprotease ZmpB, truncated YP_139835.1 1242731 R 264199 CDS YP_139836.1 55821394 3164229 complement(1243202..1243300) 1 NC_006448.1 truncated; zinc metalloprotease ZmpB, truncated 1243300 3164229 stu1408 Streptococcus thermophilus LMG 18311 zinc metalloprotease ZmpB, truncated YP_139836.1 1243202 R 264199 CDS YP_139837.1 55821395 3165402 1243667..1243927 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1243927 3165402 stu1409 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_139837.1 1243667 D 264199 CDS YP_139838.1 55821396 3164668 complement(1243982..1244083) 1 NC_006448.1 truncated; ABC transporter ATP binding protein 1244083 3164668 stu1410 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_139838.1 1243982 R 264199 CDS YP_139839.1 55821397 3165367 complement(1244114..1244680) 1 NC_006448.1 truncated; ABC transporter, truncated 1244680 3165367 stu1411 Streptococcus thermophilus LMG 18311 ABC transporter, truncated YP_139839.1 1244114 R 264199 CDS YP_139840.1 55821398 3165372 complement(1244566..1244838) 1 NC_006448.1 truncated; ABC transporter, truncated 1244838 3165372 stu1412 Streptococcus thermophilus LMG 18311 ABC transporter, truncated YP_139840.1 1244566 R 264199 CDS YP_139841.1 55821399 3165343 1245523..1247787 1 NC_006448.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1247787 3165343 stu1413 Streptococcus thermophilus LMG 18311 bifunctional glutamate--cysteine ligase/glutathione synthetase YP_139841.1 1245523 D 264199 CDS YP_139842.1 55821400 3165443 1247844..1248509 1 NC_006448.1 truncated; truncated IS1193 transposase 1248509 3165443 stu1414 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139842.1 1247844 D 264199 CDS YP_139843.1 55821401 3165467 1248807..1248977 1 NC_006448.1 truncated; truncated IS1193 transposase 1248977 3165467 stu1415 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_139843.1 1248807 D 264199 CDS YP_139844.1 55821402 3165312 complement(1249096..1251525) 1 NC_006448.1 cell division protein 1251525 ftsK 3165312 ftsK Streptococcus thermophilus LMG 18311 cell division protein YP_139844.1 1249096 R 264199 CDS YP_139845.1 55821403 3165597 complement(1251678..1252676) 1 NC_006448.1 thioredoxin reductase 1252676 trxB2 3165597 trxB2 Streptococcus thermophilus LMG 18311 thioredoxin reductase YP_139845.1 1251678 R 264199 CDS YP_139846.1 55821404 3165444 complement(1252678..1253397) 1 NC_006448.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1253397 trmD 3165444 trmD Streptococcus thermophilus LMG 18311 tRNA (guanine-N(1)-)-methyltransferase YP_139846.1 1252678 R 264199 CDS YP_139847.1 55821405 3165286 complement(1253387..1253905) 1 NC_006448.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1253905 rimM 3165286 rimM Streptococcus thermophilus LMG 18311 16S rRNA-processing protein RimM YP_139847.1 1253387 R 264199 CDS YP_139848.1 55821406 3165543 complement(1254576..1255220) 1 NC_006448.1 response regulator 1255220 rr08 3165543 rr08 Streptococcus thermophilus LMG 18311 response regulator YP_139848.1 1254576 R 264199 CDS YP_139849.1 55821407 3165377 complement(1255210..1256220) 1 NC_006448.1 sensor histidine kinase 1256220 hk08 3165377 hk08 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_139849.1 1255210 R 264199 CDS YP_139850.1 55821408 3165363 complement(1256217..1256915) 1 NC_006448.1 hypothetical protein 1256915 3165363 stu1422 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139850.1 1256217 R 264199 CDS YP_139851.1 55821409 3163953 complement(1257181..1257336) 1 NC_006448.1 truncated; potassium channel, truncated 1257336 3163953 stu1423 Streptococcus thermophilus LMG 18311 potassium channel, truncated YP_139851.1 1257181 R 264199 CDS YP_139852.1 55821410 3165563 complement(1257568..1257720) 1 NC_006448.1 truncated; potassium channel, truncated 1257720 3165563 stu1424 Streptococcus thermophilus LMG 18311 potassium channel, truncated YP_139852.1 1257568 R 264199 CDS YP_139853.1 55821411 3165410 complement(1257973..1259844) 1 NC_006448.1 protein kinase 1259844 pknB 3165410 pknB Streptococcus thermophilus LMG 18311 protein kinase YP_139853.1 1257973 R 264199 CDS YP_139854.1 55821412 3165270 complement(1259844..1260662) 1 NC_006448.1 phosphoprotein phosphatase 1260662 pppL 3165270 pppL Streptococcus thermophilus LMG 18311 phosphoprotein phosphatase YP_139854.1 1259844 R 264199 CDS YP_139855.1 55821413 3165445 complement(1260625..1261956) 1 NC_006448.1 RNA-binding protein 1261956 sunL 3165445 sunL Streptococcus thermophilus LMG 18311 RNA-binding protein YP_139855.1 1260625 R 264199 CDS YP_139856.1 55821414 3164338 complement(1261937..1262872) 1 NC_006448.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1262872 fmt 3164338 fmt Streptococcus thermophilus LMG 18311 methionyl-tRNA formyltransferase YP_139856.1 1261937 R 264199 CDS YP_139857.1 55821415 3165404 complement(1262890..1265286) 1 NC_006448.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1265286 priA 3165404 priA Streptococcus thermophilus LMG 18311 primosome assembly protein PriA YP_139857.1 1262890 R 264199 CDS YP_139858.1 55821416 3165604 complement(1265428..1265742) 1 NC_006448.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1265742 rpoZ 3165604 rpoZ Streptococcus thermophilus LMG 18311 DNA-directed RNA polymerase subunit omega YP_139858.1 1265428 R 264199 CDS YP_139859.1 55821417 3165408 complement(1265764..1266393) 1 NC_006448.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1266393 gmk 3165408 gmk Streptococcus thermophilus LMG 18311 guanylate kinase YP_139859.1 1265764 R 264199 CDS YP_139860.1 55821418 3164351 complement(1266626..1268017) 1 NC_006448.1 signal recognition particle receptor (docking protein) 1268017 ftsY 3164351 ftsY Streptococcus thermophilus LMG 18311 signal recognition particle receptor (docking protein) YP_139860.1 1266626 R 264199 CDS YP_139861.1 55821419 3165274 complement(1268031..1268846) 1 NC_006448.1 hypothetical protein 1268846 3165274 stu1433 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139861.1 1268031 R 264199 CDS YP_139862.1 55821420 3164224 complement(1268839..1269633) 1 NC_006448.1 hypothetical protein 1269633 3164224 stu1434 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139862.1 1268839 R 264199 CDS YP_139863.1 55821421 3165447 1269817..1270194 1 NC_006448.1 GntR family transcriptional regulator 1270194 3165447 stu1435 Streptococcus thermophilus LMG 18311 GntR family transcriptional regulator YP_139863.1 1269817 D 264199 CDS YP_139864.1 55821422 3165436 1270199..1270897 1 NC_006448.1 ABC transporter ATP binding protein 1270897 3165436 stu1436 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_139864.1 1270199 D 264199 CDS YP_139865.1 55821423 3164757 1270903..1271694 1 NC_006448.1 ABC transporter membrane-spanning protein 1271694 3164757 stu1437 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_139865.1 1270903 D 264199 CDS YP_139866.1 55821424 3165362 complement(1271744..1272688) 1 NC_006448.1 oligopeptide ABC uptake transporter ATP-binding protein 1272688 amiF1 3165362 amiF1 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP-binding protein YP_139866.1 1271744 R 264199 CDS YP_139867.1 55821425 3165303 complement(1272666..1273751) 1 NC_006448.1 oligopeptide ABC uptake transporter ATP-binding protein 1273751 amiE 3165303 amiE Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP-binding protein YP_139867.1 1272666 R 264199 CDS YP_139868.1 55821426 3165283 complement(1273761..1274687) 1 NC_006448.1 oligopeptide ABC uptake transporter membrane-binding protein 1274687 amiD 3165283 amiD Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-binding protein YP_139868.1 1273761 R 264199 CDS YP_139869.1 55821427 3165603 complement(1274687..1276180) 1 NC_006448.1 oligopeptide ABC uptake transporter membrane-binding protein 1276180 amiC 3165603 amiC Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter membrane-binding protein YP_139869.1 1274687 R 264199 CDS YP_139870.1 55821428 3164387 complement(1276242..1278209) 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated 1278209 3164387 stu1442 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate-binding protein, truncated YP_139870.1 1276242 R 264199 CDS YP_139871.1 55821429 3164143 1278565..1279821 1 NC_006448.1 IS1193 transposase 1279821 tnp1193 3164143 tnp1193 Streptococcus thermophilus LMG 18311 IS1193 transposase YP_139871.1 1278565 D 264199 CDS YP_139872.1 55821430 3164729 complement(1279859..1281832) 1 NC_006448.1 oligopeptide ABC uptake transporter substrate-binding protein 1281832 amiA3 3164729 amiA3 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate-binding protein YP_139872.1 1279859 R 264199 CDS YP_139873.1 55821431 3164384 complement(1282036..1282143) 1 NC_006448.1 truncated; hypothetical protein 1282143 3164384 stu1446 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139873.1 1282036 R 264199 CDS YP_139874.1 55821432 3164551 complement(1282217..1282711) 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter ATP-binding protein, truncated 1282711 3164551 stu1447 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter ATP-binding protein, truncated YP_139874.1 1282217 R 264199 CDS YP_139875.1 55821433 3165399 complement(1282818..1283018) 1 NC_006448.1 hypothetical protein 1283018 3165399 stu1449 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139875.1 1282818 R 264199 CDS YP_139876.1 55821434 3165477 1283326..1284531 1 NC_006448.1 oxalate:formate antiporter 1284531 oxlT 3165477 oxlT Streptococcus thermophilus LMG 18311 oxalate:formate antiporter YP_139876.1 1283326 D 264199 CDS YP_139877.1 55821435 3164375 complement(1284577..1285215) 1 NC_006448.1 truncated; hypothetical protein 1285215 3164375 stu1451 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139877.1 1284577 R 264199 CDS YP_139878.1 55821436 3165391 complement(1285222..1285416) 1 NC_006448.1 truncated; hypothetical protein 1285416 3165391 stu1452 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139878.1 1285222 R 264199 CDS YP_139879.1 55821437 3165349 complement(1285392..1285580) 1 NC_006448.1 truncated; hypothetical protein 1285580 3165349 stu1453 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139879.1 1285392 R 264199 CDS YP_139880.1 55821438 3164198 complement(1285680..1285985) 1 NC_006448.1 truncated; hypothetical protein 1285985 3164198 stu1454 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139880.1 1285680 R 264199 CDS YP_139881.1 55821439 3165456 complement(1286014..1286997) 1 NC_006448.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1286997 eutD 3165456 eutD Streptococcus thermophilus LMG 18311 phosphotransacetylase YP_139881.1 1286014 R 264199 CDS YP_139882.1 55821440 3164583 complement(1287011..1287907) 1 NC_006448.1 ribosomal large subunit pseudouridine synthase D 1287907 3164583 stu1456 Streptococcus thermophilus LMG 18311 ribosomal large subunit pseudouridine synthase D YP_139882.1 1287011 R 264199 CDS YP_139883.1 55821441 3165088 complement(1287904..1288743) 1 NC_006448.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1288743 ppnK 3165088 ppnK Streptococcus thermophilus LMG 18311 inorganic polyphosphate/ATP-NAD kinase YP_139883.1 1287904 R 264199 CDS YP_139884.1 55821443 3164221 complement(1288712..1289437) 1 NC_006448.1 GTP pyrophosphokinase 1289437 3164221 stu1459 Streptococcus thermophilus LMG 18311 GTP pyrophosphokinase YP_139884.1 1288712 R 264199 CDS YP_139885.1 55821442 3165502 1289401..1290057 1 NC_006448.1 hypothetical protein 1290057 3165502 stu1458 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139885.1 1289401 D 264199 CDS YP_139886.1 55821444 3164515 1290380..1291393 1 NC_006448.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1291393 prsA2 3164515 prsA2 Streptococcus thermophilus LMG 18311 ribose-phosphate pyrophosphokinase YP_139886.1 1290380 D 264199 CDS YP_139887.1 55821445 3165208 1291397..1292509 1 NC_006448.1 aminotransferase 1292509 nifS3 3165208 nifS3 Streptococcus thermophilus LMG 18311 aminotransferase YP_139887.1 1291397 D 264199 CDS YP_139888.1 55821446 3165291 1292511..1292858 1 NC_006448.1 hypothetical protein 1292858 3165291 stu1462 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139888.1 1292511 D 264199 CDS YP_139889.1 55821447 3165405 1292967..1293662 1 NC_006448.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1293662 3165405 stu1463 Streptococcus thermophilus LMG 18311 redox-sensing transcriptional repressor Rex YP_139889.1 1292967 D 264199 CDS YP_139890.1 55821448 3165334 1293655..1294350 1 NC_006448.1 glutamine amidotransferase (class I) 1294350 3165334 stu1464 Streptococcus thermophilus LMG 18311 glutamine amidotransferase (class I) YP_139890.1 1293655 D 264199 CDS YP_139891.1 55821449 3164219 complement(1294403..1295089) 1 NC_006448.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1295089 radC 3164219 radC Streptococcus thermophilus LMG 18311 DNA repair protein RadC YP_139891.1 1294403 R 264199 CDS YP_139892.1 55821450 3165162 complement(1295138..1296922) 1 NC_006448.1 polysaccharide biosynthesis protein 1296922 rgpF 3165162 rgpF Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein YP_139892.1 1295138 R 264199 CDS YP_139893.1 55821451 3165529 complement(1296919..1297974) 1 NC_006448.1 polysaccharide biosynthesis protein/ glycosyltransferase 1297974 rgpE 3165529 rgpE Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein/ glycosyltransferase YP_139893.1 1296919 R 264199 CDS YP_139894.1 55821452 3165595 complement(1297994..1299199) 1 NC_006448.1 polysaccharide ABC exporter ATP-binding protein 1299199 rgpD 3165595 rgpD Streptococcus thermophilus LMG 18311 polysaccharide ABC exporter ATP-binding protein YP_139894.1 1297994 R 264199 CDS YP_139895.1 55821453 3163792 complement(1299199..1300029) 1 NC_006448.1 polysaccharide ABC exporter membrane-spanning protein 1300029 rgpC 3163792 rgpC Streptococcus thermophilus LMG 18311 polysaccharide ABC exporter membrane-spanning protein YP_139895.1 1299199 R 264199 CDS YP_139896.1 55821454 3165531 complement(1299992..1300948) 1 NC_006448.1 polysaccharide biosynthesis protein/ rhamnosyl transferase 1300948 rgpB 3165531 rgpB Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein/ rhamnosyl transferase YP_139896.1 1299992 R 264199 CDS YP_139897.1 55821455 3163804 complement(1300945..1302111) 1 NC_006448.1 polysaccharide biosynthesis protein/ rhamnosyl transferase 1302111 rgpA 3163804 rgpA Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein/ rhamnosyl transferase YP_139897.1 1300945 R 264199 CDS YP_139898.1 55821456 3165520 complement(1302202..1303212) 1 NC_006448.1 polysaccharide biosynthesis protein rhamnosyl transferase 1303212 rgpX2 3165520 rgpX2 Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein rhamnosyl transferase YP_139898.1 1302202 R 264199 CDS YP_139899.1 55821457 3165333 complement(1303212..1304486) 1 NC_006448.1 polysaccharide biosynthesis protein transporter 1304486 rgpX3 3165333 rgpX3 Streptococcus thermophilus LMG 18311 polysaccharide biosynthesis protein transporter YP_139899.1 1303212 R 264199 CDS YP_139900.1 55821458 3165476 complement(1304479..1304811) 1 NC_006448.1 hypothetical protein 1304811 3165476 stu1481 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139900.1 1304479 R 264199 CDS YP_139901.1 55821459 3165393 complement(1304817..1305506) 1 NC_006448.1 glycosyltransferase 1305506 3165393 stu1482 Streptococcus thermophilus LMG 18311 glycosyltransferase YP_139901.1 1304817 R 264199 CDS YP_139902.1 55821460 3164725 complement(1305589..1306461) 1 NC_006448.1 dTDP-4-keto-L-rhamnose reductase 1306461 rmlD 3164725 rmlD Streptococcus thermophilus LMG 18311 dTDP-4-keto-L-rhamnose reductase YP_139902.1 1305589 R 264199 CDS YP_139903.1 55821461 3164217 complement(1306517..1307863) 1 NC_006448.1 hypothetical protein 1307863 3164217 stu1484 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139903.1 1306517 R 264199 CDS YP_139904.1 55821462 3165446 complement(1307964..1308881) 1 NC_006448.1 glycosyl transferase family protein 1308881 3165446 stu1485 Streptococcus thermophilus LMG 18311 glycosyl transferase family protein YP_139904.1 1307964 R 264199 CDS YP_139905.1 55821463 3165489 complement(1308944..1310359) 1 NC_006448.1 hypothetical protein 1310359 3165489 stu1486 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139905.1 1308944 R 264199 CDS YP_139906.1 55821464 3165486 complement(1310693..1311058) 1 NC_006448.1 hypothetical protein 1311058 3165486 stu1487 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139906.1 1310693 R 264199 CDS YP_139907.1 55821465 3165306 complement(1311082..1312191) 1 NC_006448.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1312191 rpoD 3165306 rpoD Streptococcus thermophilus LMG 18311 RNA polymerase sigma factor RpoD YP_139907.1 1311082 R 264199 CDS YP_139908.1 55821466 3164805 complement(1312195..1314006) 1 NC_006448.1 synthesizes RNA primers at the replication forks; DNA primase 1314006 dnaG 3164805 dnaG Streptococcus thermophilus LMG 18311 DNA primase YP_139908.1 1312195 R 264199 CDS YP_139909.2 161611283 3165607 complement(1314377..1314553) 1 NC_006448.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1314553 rpsU 3165607 rpsU Streptococcus thermophilus LMG 18311 30S ribosomal protein S21 YP_139909.2 1314377 R 264199 CDS YP_139910.1 55821468 3165394 complement(1314748..1315542) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1315542 3165394 stu1492 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139910.1 1314748 R 264199 CDS YP_139911.1 55821469 3165397 complement(1315635..1316747) 1 NC_006448.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 1316747 3165397 stu1493 Streptococcus thermophilus LMG 18311 transaminase YP_139911.1 1315635 R 264199 CDS YP_139912.1 55821470 3164631 complement(1317091..1317888) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1317888 3164631 stu1494 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139912.1 1317091 R 264199 CDS YP_139913.1 55821471 3165350 complement(1317885..1318721) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1318721 3165350 stu1495 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139913.1 1317885 R 264199 CDS YP_139914.1 55821472 3165602 complement(1318928..1319392) 1 NC_006448.1 MutT/nudix family protein 1319392 3165602 stu1496 Streptococcus thermophilus LMG 18311 MutT/nudix family protein YP_139914.1 1318928 R 264199 CDS YP_139915.1 55821473 3165455 complement(1319437..1321443) 1 NC_006448.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1321443 uvrB 3165455 uvrB Streptococcus thermophilus LMG 18311 excinuclease ABC subunit B YP_139915.1 1319437 R 264199 CDS YP_139916.1 55821474 3165376 complement(1321575..1322015) 1 NC_006448.1 hypothetical protein 1322015 3165376 stu1498 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139916.1 1321575 R 264199 CDS YP_139917.1 55821475 3165320 complement(1322188..1322538) 1 NC_006448.1 hypothetical protein 1322538 3165320 stu1499 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139917.1 1322188 R 264199 CDS YP_139918.1 55821476 3165323 complement(1322770..1323051) 1 NC_006448.1 hypothetical protein 1323051 3165323 stu1500 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139918.1 1322770 R 264199 CDS YP_139919.1 55821477 3165485 1323250..1325460 1 NC_006448.1 glutamine ABC uptake transporter membrane-spanning protein 1325460 gnlP 3165485 gnlP Streptococcus thermophilus LMG 18311 glutamine ABC uptake transporter membrane-spanning protein YP_139919.1 1323250 D 264199 CDS YP_139920.1 55821478 3165315 1325460..1326200 1 NC_006448.1 glutamine ABC uptake transporter ATP-binding protein 1326200 gnlQ 3165315 gnlQ Streptococcus thermophilus LMG 18311 glutamine ABC uptake transporter ATP-binding protein YP_139920.1 1325460 D 264199 CDS YP_139921.1 55821479 3164608 complement(1326273..1326470) 1 NC_006448.1 hypothetical protein 1326470 3164608 stu1503 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139921.1 1326273 R 264199 CDS YP_139922.2 161611282 3165454 complement(1326637..1327944) 1 NC_006448.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1327944 obgE 3165454 obgE Streptococcus thermophilus LMG 18311 GTPase ObgE YP_139922.2 1326637 R 264199 CDS YP_139923.1 55821481 3164848 complement(1328254..1328985) 1 NC_006448.1 ribosomal small subunit pseudouridine synthase A 1328985 rsuA2 3164848 rsuA2 Streptococcus thermophilus LMG 18311 ribosomal small subunit pseudouridine synthase A YP_139923.1 1328254 R 264199 CDS YP_139924.1 55821482 3165605 complement(1328986..1329219) 1 NC_006448.1 hypothetical protein 1329219 3165605 stu1506 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139924.1 1328986 R 264199 CDS YP_139925.1 55821483 3165601 complement(1329355..1329648) 1 NC_006448.1 hypothetical protein 1329648 3165601 stu1507 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139925.1 1329355 R 264199 CDS YP_139926.1 55821484 3165406 1329669..1329770 1 NC_006448.1 hypothetical protein 1329770 3165406 stu1508 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139926.1 1329669 D 264199 CDS YP_139927.1 55821485 3165292 1329931..1330521 1 NC_006448.1 hypothetical protein 1330521 3165292 stu1509 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139927.1 1329931 D 264199 CDS YP_139928.1 55821486 3165427 1330521..1330847 1 NC_006448.1 hypothetical protein 1330847 3165427 stu1510 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139928.1 1330521 D 264199 CDS YP_139929.1 55821487 3165423 complement(1331070..1331933) 1 NC_006448.1 MutR family transcriptional regulator 1331933 3165423 stu1511 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_139929.1 1331070 R 264199 CDS YP_139930.1 55821488 3165500 1332282..1333577 1 NC_006448.1 hypothetical protein 1333577 3165500 stu1512 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139930.1 1332282 D 264199 CDS YP_139931.1 55821489 3165331 1333579..1335150 1 NC_006448.1 peptide-2 ABC transporter ATP binding/membrane-spanning protein 1335150 3165331 stu1513 Streptococcus thermophilus LMG 18311 peptide-2 ABC transporter ATP binding/membrane-spanning protein YP_139931.1 1333579 D 264199 CDS YP_139932.1 55821490 3165084 1335432..1335863 1 NC_006448.1 hypothetical protein 1335863 3165084 stu1514 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139932.1 1335432 D 264199 CDS YP_139933.1 55821491 3165379 1335890..1336258 1 NC_006448.1 hypothetical protein 1336258 3165379 stu1515 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139933.1 1335890 D 264199 CDS YP_139934.1 55821492 3165414 complement(1336287..1336751) 1 NC_006448.1 hypothetical protein 1336751 3165414 stu1516 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139934.1 1336287 R 264199 CDS YP_139935.1 55821493 3164677 1337768..1338658 1 NC_006448.1 hypothetical protein 1338658 3164677 stu1517 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139935.1 1337768 D 264199 CDS YP_139936.1 55821494 3165448 complement(1338696..1338947) 1 NC_006448.1 hypothetical protein 1338947 3165448 stu1518 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139936.1 1338696 R 264199 CDS YP_139937.1 55821495 3165319 complement(1339159..1339806) 1 NC_006448.1 phosphoserine phosphatase 1339806 serB 3165319 serB Streptococcus thermophilus LMG 18311 phosphoserine phosphatase YP_139937.1 1339159 R 264199 CDS YP_139938.1 55821496 3165318 complement(1339918..1341612) 1 NC_006448.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 1341612 ezrA 3165318 ezrA Streptococcus thermophilus LMG 18311 septation ring formation regulator EzrA YP_139938.1 1339918 R 264199 CDS YP_139939.1 55821497 3165388 complement(1341739..1343691) 1 NC_006448.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 1343691 gyrB 3165388 gyrB Streptococcus thermophilus LMG 18311 DNA gyrase subunit B YP_139939.1 1341739 R 264199 CDS YP_139940.1 55821498 3165468 complement(1343692..1344297) 1 NC_006448.1 HAD superfamily hydrolase 1344297 3165468 stu1522 Streptococcus thermophilus LMG 18311 HAD superfamily hydrolase YP_139940.1 1343692 R 264199 CDS YP_139941.1 55821499 3163781 complement(1344338..1345060) 1 NC_006448.1 hypothetical protein 1345060 3163781 stu1523 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139941.1 1344338 R 264199 CDS YP_139942.1 55821500 3165305 complement(1345026..1345424) 1 NC_006448.1 hypothetical protein 1345424 3165305 stu1524 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139942.1 1345026 R 264199 CDS YP_139943.1 55821501 3165459 complement(1345680..1346033) 1 NC_006448.1 hypothetical protein 1346033 3165459 stu1525 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139943.1 1345680 R 264199 CDS YP_139944.1 55821502 3165102 complement(1346068..1346295) 1 NC_006448.1 truncated; methylguanine-DNA methyltransferase, truncated 1346295 3165102 stu1526 Streptococcus thermophilus LMG 18311 methylguanine-DNA methyltransferase, truncated YP_139944.1 1346068 R 264199 CDS YP_139945.1 55821503 3165592 complement(1346619..1347797) 1 NC_006448.1 D-3-phosphoglycerate dehydrogenase 1347797 serA 3165592 serA Streptococcus thermophilus LMG 18311 D-3-phosphoglycerate dehydrogenase YP_139945.1 1346619 R 264199 CDS YP_139946.1 55821504 3165591 complement(1347816..1348373) 1 NC_006448.1 acetyltransferase 1348373 3165591 stu1528 Streptococcus thermophilus LMG 18311 acetyltransferase YP_139946.1 1347816 R 264199 CDS YP_139947.1 55821505 3165038 complement(1348385..1349479) 1 NC_006448.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1349479 serC 3165038 serC Streptococcus thermophilus LMG 18311 phosphoserine aminotransferase YP_139947.1 1348385 R 264199 CDS YP_139948.1 55821506 3164790 complement(1349633..1350295) 1 NC_006448.1 truncated; transcriptional regulator, truncated 1350295 3164790 stu1530 Streptococcus thermophilus LMG 18311 transcriptional regulator, truncated YP_139948.1 1349633 R 264199 CDS YP_139949.1 55821507 3165506 complement(1350276..1350539) 1 NC_006448.1 truncated; transcriptional regulator, truncated 1350539 3165506 stu1531 Streptococcus thermophilus LMG 18311 transcriptional regulator, truncated YP_139949.1 1350276 R 264199 CDS YP_139950.1 55821508 3165401 1350585..1350980 1 NC_006448.1 glyoxalase I/lactoylglutathione lyase 1350980 gloA 3165401 gloA Streptococcus thermophilus LMG 18311 glyoxalase I/lactoylglutathione lyase YP_139950.1 1350585 D 264199 CDS YP_139951.1 55821509 3165382 complement(1351024..1351542) 1 NC_006448.1 truncated; hypothetical protein 1351542 3165382 stu1533 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139951.1 1351024 R 264199 CDS YP_139952.1 55821510 3164215 complement(1351597..1351773) 1 NC_006448.1 truncated; hypothetical protein 1351773 3164215 stu1534 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139952.1 1351597 R 264199 CDS YP_139953.1 55821511 3164214 complement(1352121..1353191) 1 NC_006448.1 putrescine/spermidine ABC transporter subtrate-binding protein 1353191 potD 3164214 potD Streptococcus thermophilus LMG 18311 putrescine/spermidine ABC transporter subtrate-binding protein YP_139953.1 1352121 R 264199 CDS YP_139954.1 55821512 3165330 complement(1353181..1353984) 1 NC_006448.1 spermidine/putrescine ABC transporter permease 1353984 potC 3165330 potC Streptococcus thermophilus LMG 18311 spermidine/putrescine ABC transporter permease YP_139954.1 1353181 R 264199 CDS YP_139955.1 55821513 3165241 complement(1353957..1354772) 1 NC_006448.1 spermidine/putrescine ABC transporter permease 1354772 potB 3165241 potB Streptococcus thermophilus LMG 18311 spermidine/putrescine ABC transporter permease YP_139955.1 1353957 R 264199 CDS YP_139956.1 55821514 3165483 complement(1354735..1355889) 1 NC_006448.1 putrescine/spermidine ABC transporter ATP-binding protein 1355889 potA 3165483 potA Streptococcus thermophilus LMG 18311 putrescine/spermidine ABC transporter ATP-binding protein YP_139956.1 1354735 R 264199 CDS YP_139957.1 55821515 3164898 complement(1355934..1356911) 1 NC_006448.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1356911 murB 3164898 murB Streptococcus thermophilus LMG 18311 UDP-N-acetylenolpyruvoylglucosamine reductase YP_139957.1 1355934 R 264199 CDS YP_139958.1 55821516 3165398 complement(1357026..1357517) 1 NC_006448.1 hydroxymethylpterin pyrophosphokinase 1357517 folK 3165398 folK Streptococcus thermophilus LMG 18311 hydroxymethylpterin pyrophosphokinase YP_139958.1 1357026 R 264199 CDS YP_139959.1 55821517 3165499 complement(1357514..1357873) 1 NC_006448.1 dihydroneopterin aldolase 1357873 folQ 3165499 folQ Streptococcus thermophilus LMG 18311 dihydroneopterin aldolase YP_139959.1 1357514 R 264199 CDS YP_139960.1 55821518 3163852 1358070..1359545 1 NC_006448.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1359545 amyL 3163852 amyL Streptococcus thermophilus LMG 18311 cytoplasmic alpha-amylase YP_139960.1 1358070 D 264199 CDS YP_139961.1 55821519 3165593 complement(1359577..1360377) 1 NC_006448.1 dihydropteroate synthase 1360377 folP 3165593 folP Streptococcus thermophilus LMG 18311 dihydropteroate synthase YP_139961.1 1359577 R 264199 CDS YP_139962.1 55821520 3165556 complement(1360406..1360969) 1 NC_006448.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1360969 folE 3165556 folE Streptococcus thermophilus LMG 18311 GTP cyclohydrolase I YP_139962.1 1360406 R 264199 CDS YP_139963.1 55821521 3164930 complement(1361115..1362959) 1 NC_006448.1 hypothetical protein 1362959 3164930 stu1545 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139963.1 1361115 R 264199 CDS YP_139964.1 55821522 3165555 complement(1363023..1364285) 1 NC_006448.1 folylpolyglutamate synthase / dihydrofolate synthase 1364285 folC2 3165555 folC2 Streptococcus thermophilus LMG 18311 folylpolyglutamate synthase / dihydrofolate synthase YP_139964.1 1363023 R 264199 CDS YP_139965.1 55821523 3163832 complement(1364428..1364676) 1 NC_006448.1 hypothetical protein 1364676 3163832 stu1547 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139965.1 1364428 R 264199 CDS YP_139966.1 55821524 3165345 complement(1364688..1364960) 1 NC_006448.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1364960 rpsP 3165345 rpsP Streptococcus thermophilus LMG 18311 30S ribosomal protein S16 YP_139966.1 1364688 R 264199 CDS YP_139967.1 55821525 3164104 1365393..1366271 1 NC_006448.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1366271 tehB 3164104 tehB Streptococcus thermophilus LMG 18311 tellurite resistance protein TehB YP_139967.1 1365393 D 264199 CDS YP_139968.1 55821526 3165610 1367425..1368252 1 NC_006448.1 3'-exo-deoxyribonuclease 1368252 exoA 3165610 exoA Streptococcus thermophilus LMG 18311 3'-exo-deoxyribonuclease YP_139968.1 1367425 D 264199 CDS YP_139969.1 55821527 3165519 1368326..1368805 1 NC_006448.1 hypothetical protein 1368805 3165519 stu1551 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139969.1 1368326 D 264199 CDS YP_139970.1 55821528 3165419 complement(1368925..1369563) 1 NC_006448.1 truncated; hypothetical protein 1369563 3165419 stu1552 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139970.1 1368925 R 264199 CDS YP_139971.1 55821529 3165507 complement(1369754..1370767) 1 NC_006448.1 similar to YegS from E. coli; lipid kinase 1370767 3165507 stu1553 Streptococcus thermophilus LMG 18311 lipid kinase YP_139971.1 1369754 R 264199 CDS YP_139972.1 55821530 3165441 complement(1370777..1372735) 1 NC_006448.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1372735 ligA 3165441 ligA Streptococcus thermophilus LMG 18311 NAD-dependent DNA ligase LigA YP_139972.1 1370777 R 264199 CDS YP_139973.1 55821531 3165496 complement(1372786..1373307) 1 NC_006448.1 hypothetical protein 1373307 3165496 stu1555 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139973.1 1372786 R 264199 CDS YP_139974.1 55821532 3165433 complement(1373386..1374351) 1 NC_006448.1 tRNA-processing ribonuclease BN 1374351 3165433 stu1556 Streptococcus thermophilus LMG 18311 tRNA-processing ribonuclease BN YP_139974.1 1373386 R 264199 CDS YP_139975.1 55821533 3165390 complement(1374353..1375213) 1 NC_006448.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1375213 pepM 3165390 pepM Streptococcus thermophilus LMG 18311 methionine aminopeptidase YP_139975.1 1374353 R 264199 CDS YP_139976.1 55821534 3164207 complement(1375257..1376555) 1 NC_006448.1 hypothetical protein 1376555 3164207 stu1558 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139976.1 1375257 R 264199 CDS YP_139977.1 55821535 3165505 complement(1376530..1377117) 1 NC_006448.1 acetyltransferase 1377117 3165505 stu1559 Streptococcus thermophilus LMG 18311 acetyltransferase YP_139977.1 1376530 R 264199 CDS YP_139978.1 55821536 3165263 complement(1377141..1378412) 1 NC_006448.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1378412 murZ 3165263 murZ Streptococcus thermophilus LMG 18311 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_139978.1 1377141 R 264199 CDS YP_139979.1 55821537 3163847 complement(1378489..1380729) 1 NC_006448.1 late competence protein required for DNA uptake 1380729 comEC 3163847 comEC Streptococcus thermophilus LMG 18311 late competence protein required for DNA uptake YP_139979.1 1378489 R 264199 CDS YP_139980.1 55821538 3165396 complement(1380719..1381414) 1 NC_006448.1 late competence protein required for DNA binding and uptake 1381414 comEA 3165396 comEA Streptococcus thermophilus LMG 18311 late competence protein required for DNA binding and uptake YP_139980.1 1380719 R 264199 CDS YP_139981.1 55821539 3165369 complement(1381522..1382277) 1 NC_006448.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 1382277 3165369 stu1563 Streptococcus thermophilus LMG 18311 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_139981.1 1381522 R 264199 CDS YP_139982.1 55821540 3165564 1382477..1383010 1 NC_006448.1 truncated; peptidoglycan GlcNAc deacetylase, truncated 1383010 3165564 stu1564 Streptococcus thermophilus LMG 18311 peptidoglycan GlcNAc deacetylase, truncated YP_139982.1 1382477 D 264199 CDS YP_139983.1 55821541 3165422 1383055..1383342 1 NC_006448.1 truncated; peptidoglycan GlcNAc deacetylase, truncated 1383342 3165422 stu1565 Streptococcus thermophilus LMG 18311 peptidoglycan GlcNAc deacetylase, truncated YP_139983.1 1383055 D 264199 CDS YP_139984.1 55821542 3165571 1383392..1384156 1 NC_006448.1 hypothetical protein 1384156 3165571 stu1566 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139984.1 1383392 D 264199 CDS YP_139985.1 55821543 3165568 1384160..1384429 1 NC_006448.1 hypothetical protein 1384429 3165568 stu1567 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139985.1 1384160 D 264199 CDS YP_139986.1 55821544 3165273 complement(1384986..1386572) 1 NC_006448.1 ATP-dependent RNA helicase 1386572 rheA 3165273 rheA Streptococcus thermophilus LMG 18311 ATP-dependent RNA helicase YP_139986.1 1384986 R 264199 CDS YP_139987.1 55821545 3165357 complement(1386763..1387671) 1 NC_006448.1 magnesium/cobalt transporter CorA 1387671 corA1 3165357 corA1 Streptococcus thermophilus LMG 18311 magnesium/cobalt transporter CorA YP_139987.1 1386763 R 264199 CDS YP_139988.1 55821546 3164872 complement(1387685..1388065) 1 NC_006448.1 hypothetical protein 1388065 3164872 stu1570 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139988.1 1387685 R 264199 CDS YP_139989.1 55821547 3164483 1388366..1388941 1 NC_006448.1 hypothetical protein 1388941 3164483 stu1571 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139989.1 1388366 D 264199 CDS YP_139990.1 55821548 3165220 1389392..1390255 1 NC_006448.1 MutR family transcriptional regulator 1390255 3165220 stu1572 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_139990.1 1389392 D 264199 CDS YP_139991.1 55821549 3165512 1390372..1391550 1 NC_006448.1 hypothetical protein 1391550 3165512 stu1573 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139991.1 1390372 D 264199 CDS YP_139992.1 55821550 3165514 complement(1391796..1393340) 1 NC_006448.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1393340 prfC 3165514 prfC Streptococcus thermophilus LMG 18311 peptide chain release factor 3 YP_139992.1 1391796 R 264199 CDS YP_139993.1 55821551 3164184 complement(1393691..1394356) 1 NC_006448.1 hypothetical protein 1394356 3164184 stu1575 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139993.1 1393691 R 264199 CDS YP_139994.1 55821552 3164421 complement(1394445..1395818) 1 NC_006448.1 UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase 1395818 murF 3164421 murF Streptococcus thermophilus LMG 18311 UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase YP_139994.1 1394445 R 264199 CDS YP_139995.1 55821553 3163772 1396065..1396658 1 NC_006448.1 hypothetical protein 1396658 3163772 stu1577 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139995.1 1396065 D 264199 CDS YP_139996.1 55821554 3164970 1396627..1397169 1 NC_006448.1 hypothetical protein 1397169 3164970 stu1578 Streptococcus thermophilus LMG 18311 hypothetical protein YP_139996.1 1396627 D 264199 CDS YP_139997.1 55821555 3164411 complement(1397408..1398262) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1398262 3164411 stu1579 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_139997.1 1397408 R 264199 CDS YP_139998.1 55821556 3165574 complement(1398305..1399126) 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 1399126 3165574 stu1580 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_139998.1 1398305 R 264199 CDS YP_139999.1 55821557 3164272 complement(1399065..1399760) 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 1399760 3164272 stu1581 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_139999.1 1399065 R 264199 CDS YP_140000.1 55821558 3165497 complement(1399702..1400382) 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 1400382 3165497 stu1582 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_140000.1 1399702 R 264199 CDS YP_140001.1 55821559 3165560 complement(1400707..1401753) 1 NC_006448.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1401753 ddl 3165560 ddl Streptococcus thermophilus LMG 18311 D-alanyl-alanine synthetase A YP_140001.1 1400707 R 264199 CDS YP_140002.1 55821560 3163810 complement(1401915..1402118) 1 NC_006448.1 copper chaperone - Cu2+-Cu+-Ag+-P-type ATPase 1402118 copZ 3163810 copZ Streptococcus thermophilus LMG 18311 copper chaperone - Cu2+-Cu+-Ag+-P-type ATPase YP_140002.1 1401915 R 264199 CDS YP_140003.1 55821561 3165059 complement(1402193..1404421) 1 NC_006448.1 Cu2+-Cu+-Ag+-P-type ATPase 1404421 copA 3165059 copA Streptococcus thermophilus LMG 18311 Cu2+-Cu+-Ag+-P-type ATPase YP_140003.1 1402193 R 264199 CDS YP_140004.1 55821562 3164177 complement(1404425..1404856) 1 NC_006448.1 negative transcriptional regulator - copper transport operon 1404856 copY 3164177 copY Streptococcus thermophilus LMG 18311 negative transcriptional regulator - copper transport operon YP_140004.1 1404425 R 264199 CDS YP_140005.1 55821563 3163859 complement(1405000..1405782) 1 NC_006448.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1405782 trpA 3163859 trpA Streptococcus thermophilus LMG 18311 tryptophan synthase subunit alpha YP_140005.1 1405000 R 264199 CDS YP_140006.1 55821564 3165265 complement(1405786..1406994) 1 NC_006448.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1406994 trpB 3165265 trpB Streptococcus thermophilus LMG 18311 tryptophan synthase subunit beta YP_140006.1 1405786 R 264199 CDS YP_140007.1 55821565 3164556 complement(1406991..1407602) 1 NC_006448.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1407602 trpF 3164556 trpF Streptococcus thermophilus LMG 18311 N-(5'-phosphoribosyl)anthranilate isomerase YP_140007.1 1406991 R 264199 CDS YP_140008.1 55821566 3164172 complement(1407559..1408326) 1 NC_006448.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1408326 trpC 3164172 trpC Streptococcus thermophilus LMG 18311 indole-3-glycerol phosphate synthase YP_140008.1 1407559 R 264199 CDS YP_140009.1 55821567 3163878 complement(1408323..1409327) 1 NC_006448.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1409327 trpD 3163878 trpD Streptococcus thermophilus LMG 18311 anthranilate phosphoribosyltransferase YP_140009.1 1408323 R 264199 CDS YP_140010.1 55821568 3164756 complement(1409418..1409984) 1 NC_006448.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1409984 trpG 3164756 trpG Streptococcus thermophilus LMG 18311 anthranilate synthase component II YP_140010.1 1409418 R 264199 CDS YP_140011.1 55821569 3165577 complement(1409981..1411351) 1 NC_006448.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1411351 trpE 3165577 trpE Streptococcus thermophilus LMG 18311 anthranilate synthase component I YP_140011.1 1409981 R 264199 CDS YP_140012.1 55821570 3163794 complement(1411413..1411703) 1 NC_006448.1 hypothetical protein 1411703 3163794 stu1594 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140012.1 1411413 R 264199 CDS YP_140013.1 55821571 3165513 complement(1412289..1412639) 1 NC_006448.1 hypothetical protein 1412639 3165513 stu1595 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140013.1 1412289 R 264199 CDS YP_140014.1 55821572 3165351 complement(1412721..1415108) 1 NC_006448.1 cation-P-type ATPase 1415108 ctpE 3165351 ctpE Streptococcus thermophilus LMG 18311 cation-P-type ATPase YP_140014.1 1412721 R 264199 CDS YP_140015.1 55821573 3164140 complement(1415341..1415736) 1 NC_006448.1 hypothetical protein 1415736 3164140 stu1597 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140015.1 1415341 R 264199 CDS YP_140016.1 55821574 3164376 1416045..1416344 1 NC_006448.1 hypothetical protein 1416344 3164376 stu1598 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140016.1 1416045 D 264199 CDS YP_140017.1 55821575 3164174 complement(1416502..1416792) 1 NC_006448.1 hypothetical protein 1416792 3164174 stu1599 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140017.1 1416502 R 264199 CDS YP_140018.1 55821576 3165140 complement(1416898..1417638) 1 NC_006448.1 MerR family transcriptional regulator 1417638 3165140 stu1600 Streptococcus thermophilus LMG 18311 MerR family transcriptional regulator YP_140018.1 1416898 R 264199 CDS YP_140019.1 55821577 3165235 complement(1417802..1418392) 1 NC_006448.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1418392 dnaQ 3165235 dnaQ Streptococcus thermophilus LMG 18311 DNA polymerase III subunit epsilon YP_140019.1 1417802 R 264199 CDS YP_140020.1 55821578 3165256 complement(1418442..1418978) 1 NC_006448.1 hypothetical protein 1418978 3165256 stu1602 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140020.1 1418442 R 264199 CDS YP_140021.1 55821579 3165232 1419423..1419842 1 NC_006448.1 hypothetical protein 1419842 3165232 stu1603 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140021.1 1419423 D 264199 CDS YP_140022.1 55821580 3164723 complement(1419990..1421708) 1 NC_006448.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1421708 ilvD1 3164723 ilvD1 Streptococcus thermophilus LMG 18311 dihydroxy-acid dehydratase YP_140022.1 1419990 R 264199 CDS YP_140023.1 55821581 3164789 1421821..1423002 1 NC_006448.1 hypothetical protein 1423002 3164789 stu1605 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140023.1 1421821 D 264199 CDS YP_140024.1 55821582 3165242 complement(1423238..1423879) 1 NC_006448.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1423879 trmB 3165242 trmB Streptococcus thermophilus LMG 18311 tRNA (guanine-N(7)-)-methyltransferase YP_140024.1 1423238 R 264199 CDS YP_140025.1 55821583 3164170 complement(1423889..1424680) 1 NC_006448.1 hypothetical protein 1424680 3164170 stu1607 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140025.1 1423889 R 264199 CDS YP_140026.1 55821584 3165251 complement(1424738..1425775) 1 NC_006448.1 ABC transporter membrane-spanning protein 1425775 3165251 stu1608 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_140026.1 1424738 R 264199 CDS YP_140027.1 55821585 3164741 complement(1425772..1426503) 1 NC_006448.1 ABC transporter ATP binding protein 1426503 3164741 stu1609 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_140027.1 1425772 R 264199 CDS YP_140028.1 55821586 3164855 1426568..1426987 1 NC_006448.1 cell cycle regulation histidine triad (HIT) protein 1426987 hit 3164855 hit Streptococcus thermophilus LMG 18311 cell cycle regulation histidine triad (HIT) protein YP_140028.1 1426568 D 264199 CDS YP_140029.1 55821587 3163744 1426984..1427292 1 NC_006448.1 hypothetical protein 1427292 3163744 stu1611 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140029.1 1426984 D 264199 CDS YP_140030.1 55821588 3165243 complement(1427844..1428014) 1 NC_006448.1 hypothetical protein 1428014 3165243 stu1612 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140030.1 1427844 R 264199 CDS YP_140031.1 55821589 3165245 complement(1428084..1428719) 1 NC_006448.1 hypothetical protein 1428719 3165245 stu1613 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140031.1 1428084 R 264199 CDS YP_140032.1 55821590 3165508 complement(1429272..1431371) 1 NC_006448.1 ATP-dependent proteinase ATP-binding subunit 1431371 clpL 3165508 clpL Streptococcus thermophilus LMG 18311 ATP-dependent proteinase ATP-binding subunit YP_140032.1 1429272 R 264199 CDS YP_140033.1 55821591 3164237 complement(1432086..1433177) 1 NC_006448.1 hypothetical protein 1433177 3164237 stu1615 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140033.1 1432086 R 264199 CDS YP_140034.1 55821592 3165217 complement(1433184..1434053) 1 NC_006448.1 hypothetical protein 1434053 3165217 stu1616 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140034.1 1433184 R 264199 CDS YP_140035.1 55821593 3164920 complement(1434249..1434602) 1 NC_006448.1 hypothetical protein 1434602 3164920 stu1617 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140035.1 1434249 R 264199 CDS YP_140036.1 55821594 3165523 complement(1434626..1435216) 1 NC_006448.1 hypothetical protein 1435216 3165523 stu1618 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140036.1 1434626 R 264199 CDS YP_140037.1 55821595 3164760 complement(1435213..1435845) 1 NC_006448.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1435845 nadD 3164760 nadD Streptococcus thermophilus LMG 18311 nicotinic acid mononucleotide adenylyltransferase YP_140037.1 1435213 R 264199 CDS YP_140038.1 55821596 3165295 complement(1435949..1436266) 1 NC_006448.1 hypothetical protein 1436266 3165295 stu1620 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140038.1 1435949 R 264199 CDS YP_140039.1 55821597 3165565 complement(1436505..1437623) 1 NC_006448.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1437623 3165565 stu1621 Streptococcus thermophilus LMG 18311 GTP-binding protein YqeH YP_140039.1 1436505 R 264199 CDS YP_140040.1 55821598 3165125 complement(1437623..1438150) 1 NC_006448.1 hypothetical protein 1438150 3165125 stu1622 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140040.1 1437623 R 264199 CDS YP_140041.1 55821599 3165298 complement(1438287..1439201) 1 NC_006448.1 drug/metabolite transporter (DMT) superfamily protein 1439201 3165298 stu1623 Streptococcus thermophilus LMG 18311 drug/metabolite transporter (DMT) superfamily protein YP_140041.1 1438287 R 264199 CDS YP_140042.1 55821600 3165494 complement(1439278..1439661) 1 NC_006448.1 hypothetical protein 1439661 3165494 stu1624 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140042.1 1439278 R 264199 CDS YP_140043.1 55821601 3163931 complement(1439759..1441201) 1 NC_006448.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1441201 gatB 3163931 gatB Streptococcus thermophilus LMG 18311 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_140043.1 1439759 R 264199 CDS YP_140044.1 55821602 3165268 complement(1441201..1442667) 1 NC_006448.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1442667 gatA 3165268 gatA Streptococcus thermophilus LMG 18311 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_140044.1 1441201 R 264199 CDS YP_140045.2 161611281 3165222 complement(1442667..1442969) 1 NC_006448.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1442969 gatC 3165222 gatC Streptococcus thermophilus LMG 18311 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_140045.2 1442667 R 264199 CDS YP_140046.1 55821604 3165420 complement(1443109..1443363) 1 NC_006448.1 hypothetical protein 1443363 3165420 stu1628 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140046.1 1443109 R 264199 CDS YP_140047.1 55821605 3165576 complement(1443376..1443585) 1 NC_006448.1 hypothetical protein 1443585 3165576 stu1629 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140047.1 1443376 R 264199 CDS YP_140048.1 55821606 3165466 complement(1443901..1444227) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 1444227 3165466 stu1630 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_140048.1 1443901 R 264199 CDS YP_140049.1 55821607 3165426 complement(1444311..1445234) 1 NC_006448.1 truncated; 6-phospho-beta-glucosidase 1445234 3165426 stu1631 Streptococcus thermophilus LMG 18311 6-phospho-beta-glucosidase YP_140049.1 1444311 R 264199 CDS YP_140050.1 55821608 3165266 complement(1445500..1446027) 1 NC_006448.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1446027 msrA2 3165266 msrA2 Streptococcus thermophilus LMG 18311 methionine sulfoxide reductase A YP_140050.1 1445500 R 264199 CDS YP_140051.1 55821609 3164743 complement(1446021..1446872) 1 NC_006448.1 lipoprotein 1446872 3164743 stu1633 Streptococcus thermophilus LMG 18311 lipoprotein YP_140051.1 1446021 R 264199 CDS YP_140052.1 55821610 3164810 complement(1446992..1447543) 1 NC_006448.1 pyrazinamidase/nicotinamidase 1447543 entB 3164810 entB Streptococcus thermophilus LMG 18311 pyrazinamidase/nicotinamidase YP_140052.1 1446992 R 264199 CDS YP_140053.1 55821611 3165478 complement(1447606..1448391) 1 NC_006448.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1448391 codY 3165478 codY Streptococcus thermophilus LMG 18311 transcriptional repressor CodY YP_140053.1 1447606 R 264199 CDS YP_140054.1 55821612 3165449 complement(1448651..1449865) 1 NC_006448.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 1449865 aspC2 3165449 aspC2 Streptococcus thermophilus LMG 18311 aminotransferase YP_140054.1 1448651 R 264199 CDS YP_140055.1 55821613 3165237 1450220..1450672 1 NC_006448.1 hypothetical protein 1450672 3165237 stu1637 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140055.1 1450220 D 264199 CDS YP_140056.1 55821614 3164905 1451006..1451260 1 NC_006448.1 truncated; hypothetical protein 1451260 3164905 stu1638 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140056.1 1451006 D 264199 CDS YP_140057.1 55821615 3165425 complement(1451729..1452109) 1 NC_006448.1 hypothetical protein 1452109 3165425 stu1639 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140057.1 1451729 R 264199 CDS YP_140058.1 55821616 3165236 complement(1452315..1453115) 1 NC_006448.1 pyruvate-formate lyase activating enzyme 1453115 pflA 3165236 pflA Streptococcus thermophilus LMG 18311 pyruvate-formate lyase activating enzyme YP_140058.1 1452315 R 264199 CDS YP_140059.1 55821617 3165262 complement(1454111..1455442) 1 NC_006448.1 hypothetical protein 1455442 hlyX 3165262 hlyX Streptococcus thermophilus LMG 18311 hypothetical protein YP_140059.1 1454111 R 264199 CDS YP_140060.1 55821618 3165380 1455555..1456337 1 NC_006448.1 ABC transporter ATP binding protein 1456337 3165380 stu1642 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_140060.1 1455555 D 264199 CDS YP_140061.1 55821619 3165464 complement(1456956..1459022) 1 NC_006448.1 Na+:H+ antiporter 1459022 nha 3165464 nha Streptococcus thermophilus LMG 18311 Na+:H+ antiporter YP_140061.1 1456956 R 264199 CDS YP_140062.1 55821620 3165229 complement(1459031..1459273) 1 NC_006448.1 hypothetical protein 1459273 3165229 stu1644 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140062.1 1459031 R 264199 CDS YP_140063.1 55821621 3165267 complement(1459270..1459818) 1 NC_006448.1 rRNA methylase 1459818 3165267 stu1645 Streptococcus thermophilus LMG 18311 rRNA methylase YP_140063.1 1459270 R 264199 CDS YP_140064.1 55821622 3165211 complement(1459815..1460759) 1 NC_006448.1 hypothetical protein 1460759 3165211 stu1646 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140064.1 1459815 R 264199 CDS YP_140065.1 55821623 3165596 complement(1460844..1461920) 1 NC_006448.1 protease 1461920 3165596 stu1647 Streptococcus thermophilus LMG 18311 protease YP_140065.1 1460844 R 264199 CDS YP_140066.1 55821624 3165530 complement(1461898..1462395) 1 NC_006448.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1462395 coaD 3165530 coaD Streptococcus thermophilus LMG 18311 phosphopantetheine adenylyltransferase YP_140066.1 1461898 R 264199 CDS YP_140067.1 55821625 3165504 complement(1462429..1462977) 1 NC_006448.1 methyltransferase 1462977 3165504 stu1649 Streptococcus thermophilus LMG 18311 methyltransferase YP_140067.1 1462429 R 264199 CDS YP_140068.1 55821626 3164148 complement(1463119..1464039) 1 NC_006448.1 thioredoxin reductase 1464039 trxB1 3164148 trxB1 Streptococcus thermophilus LMG 18311 thioredoxin reductase YP_140068.1 1463119 R 264199 CDS YP_140069.1 55821627 3165238 complement(1464105..1464329) 1 NC_006448.1 hypothetical protein 1464329 3165238 stu1651 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140069.1 1464105 R 264199 CDS YP_140070.1 55821628 3165233 complement(1464544..1465287) 1 NC_006448.1 polar amino acid ABC uptake transporter ATP-binding protein 1465287 3165233 stu1652 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter ATP-binding protein YP_140070.1 1464544 R 264199 CDS YP_140071.1 55821629 3165575 complement(1465287..1466258) 1 NC_006448.1 polar amino acid ABC uptake transporter membrane-spanning protein 1466258 3165575 stu1653 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter membrane-spanning protein YP_140071.1 1465287 R 264199 CDS YP_140072.1 55821630 3164144 complement(1466427..1467281) 1 NC_006448.1 polar amino acid ABC uptake transporter substrate binding protein 1467281 3164144 stu1654 Streptococcus thermophilus LMG 18311 polar amino acid ABC uptake transporter substrate binding protein YP_140072.1 1466427 R 264199 CDS YP_140073.1 55821631 3164825 complement(1467717..1467950) 1 NC_006448.1 hypothetical protein 1467950 3164825 stu1655 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140073.1 1467717 R 264199 CDS YP_140074.1 55821632 3163894 complement(1468248..1469351) 1 NC_006448.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1469351 dinP 3163894 dinP Streptococcus thermophilus LMG 18311 DNA polymerase IV YP_140074.1 1468248 R 264199 CDS YP_140075.1 55821633 3165358 1469630..1471939 1 NC_006448.1 pyruvate formate-lyase 1471939 pfl 3165358 pfl Streptococcus thermophilus LMG 18311 pyruvate formate-lyase YP_140075.1 1469630 D 264199 CDS YP_140076.1 55821634 3165622 1472202..1472984 1 NC_006448.1 carbonate dehydratase 1472984 cah 3165622 cah Streptococcus thermophilus LMG 18311 carbonate dehydratase YP_140076.1 1472202 D 264199 CDS YP_140077.1 55821635 3165257 1473002..1473487 1 NC_006448.1 hypothetical protein 1473487 3165257 stu1659 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140077.1 1473002 D 264199 CDS YP_140078.1 55821636 3165285 complement(1473839..1474144) 1 NC_006448.1 truncated; type I restriction-modification system specificty subunit, truncated 1474144 3165285 stu1660 Streptococcus thermophilus LMG 18311 type I restriction-modification system specificty subunit, truncated YP_140078.1 1473839 R 264199 CDS YP_140079.1 55821637 3165301 complement(1474163..1474453) 1 NC_006448.1 truncated; plasmid mobilization protein, truncated 1474453 3165301 stu1661 Streptococcus thermophilus LMG 18311 plasmid mobilization protein, truncated YP_140079.1 1474163 R 264199 CDS YP_140080.1 55821638 3165491 complement(1474458..1474676) 1 NC_006448.1 truncated; plasmid mobilization protein, truncated 1474676 3165491 stu1662 Streptococcus thermophilus LMG 18311 plasmid mobilization protein, truncated YP_140080.1 1474458 R 264199 CDS YP_140081.1 55821639 3164007 complement(1475158..1475619) 1 NC_006448.1 integrase/recombinase plasmid associated 1475619 int 3164007 int Streptococcus thermophilus LMG 18311 integrase/recombinase plasmid associated YP_140081.1 1475158 R 264199 CDS YP_140082.1 55821640 3163775 complement(1475839..1476525) 1 NC_006448.1 hypothetical protein 1476525 3163775 stu1664 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140082.1 1475839 R 264199 CDS YP_140083.1 55821641 3165219 complement(1476601..1477356) 1 NC_006448.1 hypothetical protein 1477356 3165219 stu1665 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140083.1 1476601 R 264199 CDS YP_140084.1 55821642 3164139 complement(1477353..1478003) 1 NC_006448.1 ABC transporter ATP binding protein 1478003 3164139 stu1666 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein YP_140084.1 1477353 R 264199 CDS YP_140085.1 55821643 3165118 complement(1478205..1479176) 1 NC_006448.1 hypothetical protein 1479176 3165118 stu1667 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140085.1 1478205 R 264199 CDS YP_140086.1 55821644 3164137 complement(1479161..1479928) 1 NC_006448.1 C3-degrading proteinase 1479928 cppA 3164137 cppA Streptococcus thermophilus LMG 18311 C3-degrading proteinase YP_140086.1 1479161 R 264199 CDS YP_140087.1 55821645 3165435 1480088..1480474 1 NC_006448.1 hypothetical protein 1480474 3165435 stu1670 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140087.1 1480088 D 264199 CDS YP_140088.1 55821646 3165439 complement(1480648..1481511) 1 NC_006448.1 glycerol facilitator 1481511 gla 3165439 gla Streptococcus thermophilus LMG 18311 glycerol facilitator YP_140088.1 1480648 R 264199 CDS YP_140089.1 55821647 3164134 1481632..1483899 1 NC_006448.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1483899 pepXP 3164134 pepXP Streptococcus thermophilus LMG 18311 x-prolyl-dipeptidyl aminopeptidase YP_140089.1 1481632 D 264199 CDS YP_140090.1 55821648 3165275 complement(1483979..1484359) 1 NC_006448.1 bacteriocin self-immunity protein 1484359 blpX 3165275 blpX Streptococcus thermophilus LMG 18311 bacteriocin self-immunity protein YP_140090.1 1483979 R 264199 CDS YP_140091.1 55821649 3165532 complement(1484484..1484747) 1 NC_006448.1 hypothetical protein 1484747 3165532 stu1674 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140091.1 1484484 R 264199 CDS YP_140092.1 55821650 3165296 complement(1485069..1485365) 1 NC_006448.1 immunity protein 1485365 blpI 3165296 blpI Streptococcus thermophilus LMG 18311 immunity protein YP_140092.1 1485069 R 264199 CDS YP_140093.1 55821651 3165254 complement(1485530..1486462) 1 NC_006448.1 hypothetical protein 1486462 blpT 3165254 blpT Streptococcus thermophilus LMG 18311 hypothetical protein YP_140093.1 1485530 R 264199 CDS YP_140094.1 55821652 3165246 1486599..1487339 1 NC_006448.1 IS3 familytransposase orf1 1487339 tnpSth1 3165246 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf1 YP_140094.1 1486599 D 264199 CDS YP_140095.1 55821653 3164133 1487354..1488223 1 NC_006448.1 IS3 familytransposase orf2 1488223 tnpSth1 3164133 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf2 YP_140095.1 1487354 D 264199 CDS YP_140096.1 55821654 3165231 complement(1488470..1488610) 1 NC_006448.1 truncated; pore-forming peptide, truncated 1488610 3165231 stu1680 Streptococcus thermophilus LMG 18311 pore-forming peptide, truncated YP_140096.1 1488470 R 264199 CDS YP_140097.1 55821655 3165264 complement(1488861..1489262) 1 NC_006448.1 hypothetical protein 1489262 3165264 stu1681 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140097.1 1488861 R 264199 CDS YP_140098.1 55821656 3165223 complement(1489388..1489588) 1 NC_006448.1 hypothetical protein 1489588 3165223 stu1682 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140098.1 1489388 R 264199 CDS YP_140099.1 55821657 3165418 complement(1489592..1489759) 1 NC_006448.1 hypothetical protein 1489759 3165418 stu1683 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140099.1 1489592 R 264199 CDS YP_140100.1 55821658 3165159 complement(1489856..1490029) 1 NC_006448.1 hypothetical protein 1490029 3165159 stu1684 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140100.1 1489856 R 264199 CDS YP_140101.1 55821659 3165122 complement(1490249..1490479) 1 NC_006448.1 pore-forming peptide bacteriocin 1490479 blpU 3165122 blpU Streptococcus thermophilus LMG 18311 pore-forming peptide bacteriocin YP_140101.1 1490249 R 264199 CDS YP_140102.1 55821660 3165248 1490729..1491460 1 NC_006448.1 response regulator 1491460 rr09 3165248 rr09 Streptococcus thermophilus LMG 18311 response regulator YP_140102.1 1490729 D 264199 CDS YP_140103.1 55821661 3165250 1491460..1492800 1 NC_006448.1 sensor histidine kinase 1492800 hk09 3165250 hk09 Streptococcus thermophilus LMG 18311 sensor histidine kinase YP_140103.1 1491460 D 264199 CDS YP_140104.1 55821662 3165225 complement(1492818..1492979) 1 NC_006448.1 signal peptide 1492979 blpC 3165225 blpC Streptococcus thermophilus LMG 18311 signal peptide YP_140104.1 1492818 R 264199 CDS YP_140105.1 55821663 3165260 complement(1492994..1493899) 1 NC_006448.1 truncated; bacteriocin ABC exporter accessory protein, truncated 1493899 3165260 stu1689 Streptococcus thermophilus LMG 18311 bacteriocin ABC exporter accessory protein, truncated YP_140105.1 1492994 R 264199 CDS YP_140106.1 55821664 3164152 complement(1494027..1494362) 1 NC_006448.1 truncated; bacteriocin ABC exporter accessory protein, truncated 1494362 3164152 stu1690 Streptococcus thermophilus LMG 18311 bacteriocin ABC exporter accessory protein, truncated YP_140106.1 1494027 R 264199 CDS YP_140107.1 55821665 3165209 complement(1494378..1496546) 1 NC_006448.1 bacteriocin ABC transporter ATP binding protein 1496546 blpA 3165209 blpA Streptococcus thermophilus LMG 18311 bacteriocin ABC transporter ATP binding protein YP_140107.1 1494378 R 264199 CDS YP_140108.1 55821666 3165070 1496966..1497217 1 NC_006448.1 hypothetical protein 1497217 3165070 stu1692 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140108.1 1496966 D 264199 CDS YP_140109.1 55821667 3165230 complement(1497545..1499290) 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 1499290 3165230 stu1693 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_140109.1 1497545 R 264199 CDS YP_140110.1 55821668 3164294 complement(1499283..1501040) 1 NC_006448.1 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 1501040 3164294 stu1694 Streptococcus thermophilus LMG 18311 lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein YP_140110.1 1499283 R 264199 CDS YP_140111.1 55821669 3165352 complement(1501639..1502166) 1 NC_006448.1 hypothetical protein 1502166 3165352 stu1695 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140111.1 1501639 R 264199 CDS YP_140112.1 55821670 3165215 complement(1502168..1503337) 1 NC_006448.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1503337 3165215 stu1696 Streptococcus thermophilus LMG 18311 ribosomal RNA large subunit methyltransferase N YP_140112.1 1502168 R 264199 CDS YP_140113.1 55821671 3165562 complement(1503341..1504063) 1 NC_006448.1 hypothetical protein 1504063 3165562 stu1697 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140113.1 1503341 R 264199 CDS YP_140114.1 55821672 3165244 complement(1504118..1505473) 1 NC_006448.1 hypothetical protein 1505473 3165244 stu1698 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140114.1 1504118 R 264199 CDS YP_140115.1 55821673 3165212 complement(1506322..1507665) 1 NC_006448.1 ATP-dependent RNA helicase 1507665 rheB 3165212 rheB Streptococcus thermophilus LMG 18311 ATP-dependent RNA helicase YP_140115.1 1506322 R 264199 CDS YP_140116.1 55821674 3165249 complement(1507740..1508762) 1 NC_006448.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1508762 mraY 3165249 mraY Streptococcus thermophilus LMG 18311 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_140116.1 1507740 R 264199 CDS YP_140117.1 55821675 3165253 complement(1508764..1511031) 1 NC_006448.1 penicillin binding protein 2X 1511031 pbp2X 3165253 pbp2X Streptococcus thermophilus LMG 18311 penicillin binding protein 2X YP_140117.1 1508764 R 264199 CDS YP_140118.1 55821676 3165279 complement(1511035..1511355) 1 NC_006448.1 cell division protein 1511355 ftsL 3165279 ftsL Streptococcus thermophilus LMG 18311 cell division protein YP_140118.1 1511035 R 264199 CDS YP_140119.1 55821677 3165541 complement(1511358..1512422) 1 NC_006448.1 S-adenosyl-methyltransferase MraW 1512422 mraW 3165541 mraW Streptococcus thermophilus LMG 18311 S-adenosyl-methyltransferase MraW YP_140119.1 1511358 R 264199 CDS YP_140120.1 55821678 3165599 complement(1512476..1513471) 1 NC_006448.1 hypothetical protein 1513471 3165599 stu1704 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140120.1 1512476 R 264199 CDS YP_140121.1 55821679 3164122 complement(1513739..1513834) 1 NC_006448.1 hypothetical protein 1513834 3164122 stu1707 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140121.1 1513739 R 264199 CDS YP_140122.1 55821680 3165227 complement(1514108..1514464) 1 NC_006448.1 hypothetical protein 1514464 3165227 stu1708 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140122.1 1514108 R 264199 CDS YP_140123.1 55821681 3165247 complement(1514684..1514953) 1 NC_006448.1 hypothetical protein 1514953 3165247 stu1709 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140123.1 1514684 R 264199 CDS YP_140124.1 55821682 3165228 complement(1515334..1516584) 1 NC_006448.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1516584 proA 3165228 proA Streptococcus thermophilus LMG 18311 gamma-glutamyl phosphate reductase YP_140124.1 1515334 R 264199 CDS YP_140125.1 55821683 3165308 complement(1516586..1517389) 1 NC_006448.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1517389 proB 3165308 proB Streptococcus thermophilus LMG 18311 gamma-glutamyl kinase YP_140125.1 1516586 R 264199 CDS YP_140126.1 55821684 3165539 complement(1517510..1519099) 1 NC_006448.1 hypothetical protein 1519099 3165539 stu1712 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140126.1 1517510 R 264199 CDS YP_140127.1 55821685 3163916 complement(1519102..1519602) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1519602 3163916 stu1713 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_140127.1 1519102 R 264199 CDS YP_140128.1 55821686 3165527 complement(1519556..1519834) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1519834 3165527 stu1714 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_140128.1 1519556 R 264199 CDS YP_140129.1 55821687 3165214 1520108..1520737 1 NC_006448.1 hypothetical protein 1520737 3165214 stu1715 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140129.1 1520108 D 264199 CDS YP_140130.1 55821688 3165569 complement(1521235..1524888) 1 NC_006448.1 ATP-dependent exonuclease subunit A 1524888 rexA 3165569 rexA Streptococcus thermophilus LMG 18311 ATP-dependent exonuclease subunit A YP_140130.1 1521235 R 264199 CDS YP_140131.1 55821689 3165558 complement(1524878..1528198) 1 NC_006448.1 ATP-dependent exonuclease subunit B 1528198 rexB 3165558 rexB Streptococcus thermophilus LMG 18311 ATP-dependent exonuclease subunit B YP_140131.1 1524878 R 264199 CDS YP_140132.1 55821690 3165528 complement(1528887..1529339) 1 NC_006448.1 hypothetical protein 1529339 3165528 stu1718 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140132.1 1528887 R 264199 CDS YP_140133.1 55821691 3165259 complement(1529682..1529822) 1 NC_006448.1 hypothetical protein 1529822 3165259 stu1719 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140133.1 1529682 R 264199 CDS YP_140134.1 55821692 3165472 complement(1530040..1530660) 1 NC_006448.1 hypothetical protein 1530660 3165472 stu1720 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140134.1 1530040 R 264199 CDS YP_140135.1 55821693 3165210 complement(1531122..1531988) 1 NC_006448.1 hypothetical protein 1531988 3165210 stu1721 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140135.1 1531122 R 264199 CDS YP_140136.1 55821694 3165553 complement(1531975..1532202) 1 NC_006448.1 hypothetical protein 1532202 3165553 stu1722 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140136.1 1531975 R 264199 CDS YP_140137.1 55821695 3165434 complement(1532262..1533647) 1 NC_006448.1 hypothetical protein 1533647 3165434 stu1723 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140137.1 1532262 R 264199 CDS YP_140138.1 55821696 3164329 1533718..1534686 1 NC_006448.1 L-asparaginase 1534686 ansB 3164329 ansB Streptococcus thermophilus LMG 18311 L-asparaginase YP_140138.1 1533718 D 264199 CDS YP_140139.1 55821697 3163752 complement(1535455..1537473) 1 NC_006448.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1537473 recG 3163752 recG Streptococcus thermophilus LMG 18311 ATP-dependent DNA helicase RecG YP_140139.1 1535455 R 264199 CDS YP_140140.1 55821698 3165218 complement(1537602..1538705) 1 NC_006448.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1538705 alr 3165218 alr Streptococcus thermophilus LMG 18311 alanine racemase YP_140140.1 1537602 R 264199 CDS YP_140141.1 55821699 3165239 complement(1538726..1539085) 1 NC_006448.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1539085 acpS 3165239 acpS Streptococcus thermophilus LMG 18311 4'-phosphopantetheinyl transferase YP_140141.1 1538726 R 264199 CDS YP_140142.1 55821700 3165579 complement(1539089..1540120) 1 NC_006448.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1540120 aroG1 3165579 aroG1 Streptococcus thermophilus LMG 18311 phospho-2-dehydro-3-deoxyheptonate aldolase YP_140142.1 1539089 R 264199 CDS YP_140143.1 55821701 3165269 complement(1540218..1541249) 1 NC_006448.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1541249 aroG2 3165269 aroG2 Streptococcus thermophilus LMG 18311 phospho-2-dehydro-3-deoxyheptonate aldolase YP_140143.1 1540218 R 264199 CDS YP_140144.1 55821702 3164802 complement(1541273..1543822) 1 NC_006448.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1543822 secA 3164802 secA Streptococcus thermophilus LMG 18311 preprotein translocase subunit SecA YP_140144.1 1541273 R 264199 CDS YP_140145.1 55821703 3165550 complement(1544005..1544262) 1 NC_006448.1 hypothetical protein 1544262 3165550 stu1731 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140145.1 1544005 R 264199 CDS YP_140146.1 55821704 3165258 complement(1544349..1545296) 1 NC_006448.1 mannose-6-phosphate isomerase 1545296 pmi1 3165258 pmi1 Streptococcus thermophilus LMG 18311 mannose-6-phosphate isomerase YP_140146.1 1544349 R 264199 CDS YP_140147.1 55821705 3165566 complement(1545362..1546255) 1 NC_006448.1 fructokinase 1546255 scrK 3165566 scrK Streptococcus thermophilus LMG 18311 fructokinase YP_140147.1 1545362 R 264199 CDS YP_140148.1 55821706 3165536 complement(1546440..1548386) 1 NC_006448.1 sucrose PTS component II 1548386 scrA 3165536 scrA Streptococcus thermophilus LMG 18311 sucrose PTS component II YP_140148.1 1546440 R 264199 CDS YP_140149.1 55821707 3164935 1548530..1549972 1 NC_006448.1 sucrose-6-phosphate hydrolase 1549972 scrB 3164935 scrB Streptococcus thermophilus LMG 18311 sucrose-6-phosphate hydrolase YP_140149.1 1548530 D 264199 CDS YP_140150.1 55821708 3165429 1549981..1550211 1 NC_006448.1 truncated; sucrose regulon regulatory protein, truncated 1550211 3165429 stu1736 Streptococcus thermophilus LMG 18311 sucrose regulon regulatory protein, truncated YP_140150.1 1549981 D 264199 CDS YP_140151.1 55821709 3164318 1550305..1550946 1 NC_006448.1 truncated; sucrose regulon regulatory protein, truncated 1550946 3164318 stu1737 Streptococcus thermophilus LMG 18311 sucrose regulon regulatory protein, truncated YP_140151.1 1550305 D 264199 CDS YP_140152.1 55821710 3164774 complement(1551036..1551470) 1 NC_006448.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1551470 nusB 3164774 nusB Streptococcus thermophilus LMG 18311 transcription antitermination protein NusB YP_140152.1 1551036 R 264199 CDS YP_140153.1 55821711 3165049 complement(1551463..1551894) 1 NC_006448.1 hypothetical protein 1551894 3165049 stu1739 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140153.1 1551463 R 264199 CDS YP_140154.1 55821712 3163904 complement(1551923..1552483) 1 NC_006448.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1552483 efp 3163904 efp Streptococcus thermophilus LMG 18311 elongation factor P YP_140154.1 1551923 R 264199 CDS YP_140155.1 55821713 3163958 complement(1552596..1553066) 1 NC_006448.1 late competence protein required for DNA binding and uptake 1553066 comEB 3163958 comEB Streptococcus thermophilus LMG 18311 late competence protein required for DNA binding and uptake YP_140155.1 1552596 R 264199 CDS YP_140156.1 55821714 3164498 complement(1553070..1554131) 1 NC_006448.1 aminopeptidase 1554131 pepP 3164498 pepP Streptococcus thermophilus LMG 18311 aminopeptidase YP_140156.1 1553070 R 264199 CDS YP_140157.1 55821715 3165567 complement(1554321..1554749) 1 NC_006448.1 hypothetical protein 1554749 3165567 stu1743 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140157.1 1554321 R 264199 CDS YP_140158.1 55821716 3165170 complement(1554794..1555225) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1555225 3165170 stu1744 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_140158.1 1554794 R 264199 CDS YP_140159.1 55821717 3164585 complement(1555357..1555593) 1 NC_006448.1 truncated; ABC transporter ATP binding protein, truncated 1555593 3164585 stu1745 Streptococcus thermophilus LMG 18311 ABC transporter ATP binding protein, truncated YP_140159.1 1555357 R 264199 CDS YP_140160.1 55821718 3164131 complement(1555933..1556124) 1 NC_006448.1 hypothetical protein 1556124 3164131 stu1746 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140160.1 1555933 R 264199 CDS YP_140161.1 55821719 3164673 complement(1556286..1556558) 1 NC_006448.1 hypothetical protein 1556558 3164673 stu1747 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140161.1 1556286 R 264199 CDS YP_140162.1 55821720 3164445 complement(1556652..1559477) 1 NC_006448.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1559477 uvrA 3164445 uvrA Streptococcus thermophilus LMG 18311 excinuclease ABC subunit A YP_140162.1 1556652 R 264199 CDS YP_140163.1 55821721 3165135 1559786..1560730 1 NC_006448.1 magnesium/cobalt transporter CorA 1560730 corA2 3165135 corA2 Streptococcus thermophilus LMG 18311 magnesium/cobalt transporter CorA YP_140163.1 1559786 D 264199 CDS YP_140164.1 55821722 3164513 1560801..1561472 1 NC_006448.1 hypothetical protein 1561472 3164513 stu1750 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140164.1 1560801 D 264199 CDS YP_140165.1 55821723 3163807 1561589..1562470 1 NC_006448.1 hypothetical protein 1562470 3163807 stu1751 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140165.1 1561589 D 264199 CDS YP_140166.1 55821724 3164530 complement(1562597..1562836) 1 NC_006448.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1562836 rpsR 3164530 rpsR Streptococcus thermophilus LMG 18311 30S ribosomal protein S18 YP_140166.1 1562597 R 264199 CDS YP_140167.1 55821725 3163824 complement(1562878..1563396) 1 NC_006448.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1563396 ssbB 3163824 ssbB Streptococcus thermophilus LMG 18311 single-stranded DNA-binding protein YP_140167.1 1562878 R 264199 CDS YP_140168.2 161611280 3164015 complement(1563408..1563698) 1 NC_006448.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1563698 rpsF 3164015 rpsF Streptococcus thermophilus LMG 18311 30S ribosomal protein S6 YP_140168.2 1563408 R 264199 CDS YP_140169.1 55821727 3164857 1563917..1564249 1 NC_006448.1 hypothetical protein 1564249 3164857 stu1755 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140169.1 1563917 D 264199 CDS YP_140170.1 55821728 3164828 1564287..1564871 1 NC_006448.1 hypothetical protein 1564871 3164828 stu1756 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140170.1 1564287 D 264199 CDS YP_140171.1 55821729 3163777 1565536..1566687 1 NC_006448.1 A/G-specific adenine glycosylase 1566687 mutY 3163777 mutY Streptococcus thermophilus LMG 18311 A/G-specific adenine glycosylase YP_140171.1 1565536 D 264199 CDS YP_140172.1 55821730 3164106 complement(1567014..1567265) 1 NC_006448.1 hypothetical protein 1567265 3164106 stu1758 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140172.1 1567014 R 264199 CDS YP_140173.1 55821731 3164537 complement(1567368..1567580) 1 NC_006448.1 hypothetical protein 1567580 3164537 stu1759 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140173.1 1567368 R 264199 CDS YP_140174.1 55821732 3165082 complement(1567583..1567927) 1 NC_006448.1 hypothetical protein 1567927 3165082 stu1760 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140174.1 1567583 R 264199 CDS YP_140175.1 55821733 3165002 complement(1568515..1571154) 1 NC_006448.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1571154 polA 3165002 polA Streptococcus thermophilus LMG 18311 DNA polymerase I YP_140175.1 1568515 R 264199 CDS YP_140176.1 55821734 3165046 1571361..1573712 1 NC_006448.1 DNA mismatch repair protein 1573712 mutS2 3165046 mutS2 Streptococcus thermophilus LMG 18311 DNA mismatch repair protein YP_140176.1 1571361 D 264199 CDS YP_140177.1 55821735 3165163 complement(1573814..1574356) 1 NC_006448.1 hypothetical protein 1574356 3165163 stu1763 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140177.1 1573814 R 264199 CDS YP_140178.1 55821736 3165128 complement(1574353..1574670) 1 NC_006448.1 hypothetical protein 1574670 3165128 stu1764 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140178.1 1574353 R 264199 CDS YP_140179.1 55821737 3163788 1574984..1575874 1 NC_006448.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1575874 rnhB 3163788 rnhB Streptococcus thermophilus LMG 18311 ribonuclease HIII YP_140179.1 1574984 D 264199 CDS YP_140180.1 55821738 3165578 1575893..1576516 1 NC_006448.1 signal peptidase I 1576516 sipA 3165578 sipA Streptococcus thermophilus LMG 18311 signal peptidase I YP_140180.1 1575893 D 264199 CDS YP_140181.1 55821739 3164800 1576578..1579082 1 NC_006448.1 exodeoxyribonuclease V 1579082 recD 3164800 recD Streptococcus thermophilus LMG 18311 exodeoxyribonuclease V YP_140181.1 1576578 D 264199 CDS YP_140182.1 55821740 3164976 complement(1579138..1579464) 1 NC_006448.1 hypothetical protein 1579464 3164976 stu1768 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140182.1 1579138 R 264199 CDS YP_140183.1 55821741 3163914 complement(1579451..1580149) 1 NC_006448.1 branched chain amino acid exporter (LIV-E) family protein 1580149 3163914 stu1769 Streptococcus thermophilus LMG 18311 branched chain amino acid exporter (LIV-E) family protein YP_140183.1 1579451 R 264199 CDS YP_140184.1 55821742 3164555 complement(1580195..1581208) 1 NC_006448.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1581208 gcp 3164555 gcp Streptococcus thermophilus LMG 18311 DNA-binding/iron metalloprotein/AP endonuclease YP_140184.1 1580195 R 264199 CDS YP_140185.1 55821743 3164761 complement(1581208..1581663) 1 NC_006448.1 ribosomal-protein-alanine acetyltransferase 1581663 rimI 3164761 rimI Streptococcus thermophilus LMG 18311 ribosomal-protein-alanine acetyltransferase YP_140185.1 1581208 R 264199 CDS YP_140186.1 55821744 3164360 complement(1581623..1582384) 1 NC_006448.1 glycoprotein endopeptidase 1582384 3164360 stu1772 Streptococcus thermophilus LMG 18311 glycoprotein endopeptidase YP_140186.1 1581623 R 264199 CDS YP_140187.1 55821745 3164468 1582573..1582803 1 NC_006448.1 hypothetical protein 1582803 3164468 stu1773 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140187.1 1582573 D 264199 CDS YP_140188.1 55821746 3164251 1582808..1584490 1 NC_006448.1 metallo-beta-lactamase superfamily protein 1584490 3164251 stu1774 Streptococcus thermophilus LMG 18311 metallo-beta-lactamase superfamily protein YP_140188.1 1582808 D 264199 CDS YP_140189.1 55821747 3164746 complement(1584726..1584905) 1 NC_006448.1 glucan-binding protein 1584905 3164746 stu1775 Streptococcus thermophilus LMG 18311 glucan-binding protein YP_140189.1 1584726 R 264199 CDS YP_140190.1 55821748 3164916 complement(1585316..1586686) 1 NC_006448.1 glutamine synthetase 1586686 gnlA 3164916 gnlA Streptococcus thermophilus LMG 18311 glutamine synthetase YP_140190.1 1585316 R 264199 CDS YP_140191.1 55821749 3165047 complement(1586708..1587082) 1 NC_006448.1 glutamine synthetase transcriptional regulatorMerR family 1587082 gnlR 3165047 gnlR Streptococcus thermophilus LMG 18311 glutamine synthetase transcriptional regulatorMerR family YP_140191.1 1586708 R 264199 CDS YP_140192.1 55821750 3165124 complement(1587256..1587759) 1 NC_006448.1 hypothetical protein 1587759 3165124 stu1778 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140192.1 1587256 R 264199 CDS YP_140193.1 55821751 3163808 1588004..1588141 1 NC_006448.1 truncated; truncated IS1193 transposase 1588141 3163808 stu1779 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_140193.1 1588004 D 264199 CDS YP_140194.1 55821752 3164359 1588138..1588344 1 NC_006448.1 truncated; truncated IS1193 transposase 1588344 3164359 stu1780 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_140194.1 1588138 D 264199 CDS YP_140195.1 55821753 3164441 1588642..1588812 1 NC_006448.1 truncated; truncated IS1193 transposase 1588812 3164441 stu1781 Streptococcus thermophilus LMG 18311 truncated IS1193 transposase YP_140195.1 1588642 D 264199 CDS YP_140196.1 55821754 3164736 complement(1588885..1590084) 1 NC_006448.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1590084 pgk 3164736 pgk Streptococcus thermophilus LMG 18311 phosphoglycerate kinase YP_140196.1 1588885 R 264199 CDS YP_140197.1 55821755 3164168 complement(1590337..1590585) 1 NC_006448.1 truncated; hypothetical protein 1590585 3164168 stu1783 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140197.1 1590337 R 264199 CDS YP_140198.1 55821756 3163790 1590700..1590984 1 NC_006448.1 truncated; hypothetical protein 1590984 3163790 stu1784 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140198.1 1590700 D 264199 CDS YP_140199.1 55821757 3164827 1591047..1591235 1 NC_006448.1 truncated; hypothetical protein 1591235 3164827 stu1785 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140199.1 1591047 D 264199 CDS YP_140200.1 55821758 3164888 1591211..1591549 1 NC_006448.1 truncated; hypothetical protein 1591549 3164888 stu1786 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140200.1 1591211 D 264199 CDS YP_140201.1 55821759 3164497 1591563..1592051 1 NC_006448.1 truncated; hypothetical protein 1592051 3164497 stu1787 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140201.1 1591563 D 264199 CDS YP_140202.1 55821760 3164958 complement(1592201..1593238) 1 NC_006448.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1593238 gapA1 3164958 gapA1 Streptococcus thermophilus LMG 18311 glyceraldehyde-3-phosphate dehydrogenase YP_140202.1 1592201 R 264199 CDS YP_140203.1 55821761 3164343 complement(1593398..1595479) 1 NC_006448.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1595479 fus 3164343 fus Streptococcus thermophilus LMG 18311 elongation factor G YP_140203.1 1593398 R 264199 CDS YP_140204.1 55821762 3164156 complement(1595700..1596170) 1 NC_006448.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1596170 rpsG 3164156 rpsG Streptococcus thermophilus LMG 18311 30S ribosomal protein S7 YP_140204.1 1595700 R 264199 CDS YP_140205.1 55821763 3164722 complement(1596189..1596602) 1 NC_006448.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1596602 rpsL 3164722 rpsL Streptococcus thermophilus LMG 18311 30S ribosomal protein S12 YP_140205.1 1596189 R 264199 CDS YP_140206.1 55821764 3163833 complement(1596832..1597872) 1 NC_006448.1 IS1239 transposase 1597872 tnp1239 3163833 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_140206.1 1596832 R 264199 CDS YP_140207.1 55821765 3164681 complement(1598064..1598888) 1 NC_006448.1 pur operon repressor 1598888 purR 3164681 purR Streptococcus thermophilus LMG 18311 pur operon repressor YP_140207.1 1598064 R 264199 CDS YP_140208.1 55821766 3163923 complement(1598982..1599935) 1 NC_006448.1 CMP-binding factor 1599935 cbf 3163923 cbf Streptococcus thermophilus LMG 18311 CMP-binding factor YP_140208.1 1598982 R 264199 CDS YP_140209.1 55821767 3164028 complement(1599913..1601187) 1 NC_006448.1 hypothetical protein 1601187 3164028 stu1795 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140209.1 1599913 R 264199 CDS YP_140210.1 55821768 3164239 complement(1601189..1601821) 1 NC_006448.1 hypothetical protein 1601821 3164239 stu1796 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140210.1 1601189 R 264199 CDS YP_140211.1 55821769 3164862 complement(1601814..1602533) 1 NC_006448.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1602533 rpe 3164862 rpe Streptococcus thermophilus LMG 18311 ribulose-phosphate 3-epimerase YP_140211.1 1601814 R 264199 CDS YP_140212.1 55821770 3165035 complement(1602481..1603353) 1 NC_006448.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1603353 3165035 stu1798 Streptococcus thermophilus LMG 18311 ribosome-associated GTPase YP_140212.1 1602481 R 264199 CDS YP_140213.1 55821771 3164047 complement(1603610..1604482) 1 NC_006448.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1604482 ksgA 3164047 ksgA Streptococcus thermophilus LMG 18311 dimethyladenosine transferase YP_140213.1 1603610 R 264199 CDS YP_140214.1 55821772 3164311 complement(1604627..1605187) 1 NC_006448.1 topoisomerase/primase 1605187 3164311 stu1800 Streptococcus thermophilus LMG 18311 topoisomerase/primase YP_140214.1 1604627 R 264199 CDS YP_140215.1 55821773 3164327 complement(1605180..1605956) 1 NC_006448.1 deoxyribonuclease 1605956 tatD 3164327 tatD Streptococcus thermophilus LMG 18311 deoxyribonuclease YP_140215.1 1605180 R 264199 CDS YP_140216.1 55821774 3163845 complement(1606010..1606462) 1 NC_006448.1 hypothetical protein 1606462 3163845 stu1802 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140216.1 1606010 R 264199 CDS YP_140217.1 55821775 3163813 complement(1606501..1606815) 1 NC_006448.1 thioredoxin 1606815 trxA1 3163813 trxA1 Streptococcus thermophilus LMG 18311 thioredoxin YP_140217.1 1606501 R 264199 CDS YP_140218.1 55821776 3164640 1607011..1607793 1 NC_006448.1 hypothetical protein 1607793 3164640 stu1804 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140218.1 1607011 D 264199 CDS YP_140219.1 55821777 3164936 complement(1608254..1608589) 1 NC_006448.1 bacteriocin transport accessory protein 1608589 bta 3164936 bta Streptococcus thermophilus LMG 18311 bacteriocin transport accessory protein YP_140219.1 1608254 R 264199 CDS YP_140220.1 55821778 3165034 complement(1614422..1615564) 1 NC_006448.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1615564 tgt 3165034 tgt Streptococcus thermophilus LMG 18311 queuine tRNA-ribosyltransferase YP_140220.1 1614422 R 264199 CDS YP_140221.1 55821779 3164728 complement(1615817..1616290) 1 NC_006448.1 IS200 family transposase 1616290 tnp657 3164728 tnp657 Streptococcus thermophilus LMG 18311 IS200 family transposase YP_140221.1 1615817 R 264199 CDS YP_140222.1 55821780 3164347 complement(1616468..1616602) 1 NC_006448.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1616602 rpmH 3164347 rpmH Streptococcus thermophilus LMG 18311 50S ribosomal protein L34 YP_140222.1 1616468 R 264199 CDS YP_140223.1 55821781 3164536 complement(1617490..1618539) 1 NC_006448.1 DNA/RNA-binding protein 1618539 jag 3164536 jag Streptococcus thermophilus LMG 18311 DNA/RNA-binding protein YP_140223.1 1617490 R 264199 CDS YP_140224.1 55821782 3164283 complement(1618551..1619357) 1 NC_006448.1 cytochrome oxidase biogenesis (Oxa1) family protein, SpoIIIJ 1619357 3164283 stu1810 Streptococcus thermophilus LMG 18311 cytochrome oxidase biogenesis (Oxa1) family protein, SpoIIIJ YP_140224.1 1618551 R 264199 CDS YP_140225.1 55821783 3165136 complement(1619472..1619807) 1 NC_006448.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1619807 rnpA 3165136 rnpA Streptococcus thermophilus LMG 18311 ribonuclease P YP_140225.1 1619472 R 264199 CDS YP_140226.1 55821784 3164735 complement(1619892..1621367) 1 NC_006448.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1621367 argH 3164735 argH Streptococcus thermophilus LMG 18311 argininosuccinate lyase YP_140226.1 1619892 R 264199 CDS YP_140227.2 161611279 3164282 complement(1621606..1622805) 1 NC_006448.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 1622805 argG 3164282 argG Streptococcus thermophilus LMG 18311 argininosuccinate synthase YP_140227.2 1621606 R 264199 CDS YP_140228.1 55821786 3164094 complement(1623708..1625162) 1 NC_006448.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1625162 gltX 3164094 gltX Streptococcus thermophilus LMG 18311 glutamyl-tRNA synthetase YP_140228.1 1623708 R 264199 CDS YP_140229.1 55821787 3164466 complement(1625503..1625976) 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated 1625976 3164466 stu1815 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate-binding protein, truncated YP_140229.1 1625503 R 264199 CDS YP_140230.1 55821788 3164216 complement(1625973..1626398) 1 NC_006448.1 truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated 1626398 3164216 stu1816 Streptococcus thermophilus LMG 18311 oligopeptide ABC uptake transporter substrate-binding protein, truncated YP_140230.1 1625973 R 264199 CDS YP_140231.2 161611278 3165050 complement(1626490..1627179) 1 NC_006448.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1627179 rplA 3165050 rplA Streptococcus thermophilus LMG 18311 50S ribosomal protein L1 YP_140231.2 1626490 R 264199 CDS YP_140232.1 55821790 3163783 complement(1627279..1627704) 1 NC_006448.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1627704 rplK 3163783 rplK Streptococcus thermophilus LMG 18311 50S ribosomal protein L11 YP_140232.1 1627279 R 264199 CDS YP_140233.1 55821791 3164531 1627876..1628229 1 NC_006448.1 hypothetical protein 1628229 3164531 stu1819 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140233.1 1627876 D 264199 CDS YP_140234.1 55821792 3164334 complement(1628321..1628818) 1 NC_006448.1 hypothetical protein 1628818 3164334 stu1820 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140234.1 1628321 R 264199 CDS YP_140235.1 55821793 3164011 complement(1628986..1629186) 1 NC_006448.1 truncated; hypothetical protein 1629186 3164011 stu1821 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140235.1 1628986 R 264199 CDS YP_140236.1 55821794 3165174 complement(1629180..1629410) 1 NC_006448.1 truncated; hypothetical protein 1629410 3165174 stu1822 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140236.1 1629180 R 264199 CDS YP_140237.1 55821795 3165032 complement(1629750..1630997) 1 NC_006448.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1630997 radA 3165032 radA Streptococcus thermophilus LMG 18311 DNA repair protein RadA YP_140237.1 1629750 R 264199 CDS YP_140238.1 55821796 3163785 complement(1631289..1631735) 1 NC_006448.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1631735 dut 3163785 dut Streptococcus thermophilus LMG 18311 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_140238.1 1631289 R 264199 CDS YP_140239.1 55821797 3164526 1631913..1632329 1 NC_006448.1 truncated; oxidoreductase, truncated 1632329 3164526 stu1825 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_140239.1 1631913 D 264199 CDS YP_140240.1 55821798 3164932 1632326..1632544 1 NC_006448.1 truncated; oxidoreductase, truncated 1632544 3164932 stu1826 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_140240.1 1632326 D 264199 CDS YP_140241.1 55821799 3164298 1632572..1632799 1 NC_006448.1 truncated; oxidoreductase, truncated 1632799 3164298 stu1827 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_140241.1 1632572 D 264199 CDS YP_140242.1 55821800 3165044 1632823..1633542 1 NC_006448.1 truncated; oxidoreductase, truncated 1633542 3165044 stu1828 Streptococcus thermophilus LMG 18311 oxidoreductase, truncated YP_140242.1 1632823 D 264199 CDS YP_140243.1 55821801 3164257 1633749..1633931 1 NC_006448.1 truncated; formate/nitrite transporter family protein, truncated 1633931 3164257 stu1829 Streptococcus thermophilus LMG 18311 formate/nitrite transporter family protein, truncated YP_140243.1 1633749 D 264199 CDS YP_140244.1 55821802 3165154 1634019..1634450 1 NC_006448.1 truncated; formate/nitrite transporter family protein, truncated 1634450 3165154 stu1830 Streptococcus thermophilus LMG 18311 formate/nitrite transporter family protein, truncated YP_140244.1 1634019 D 264199 CDS YP_140245.1 55821803 3164946 1634459..1634914 1 NC_006448.1 hypothetical protein 1634914 3164946 stu1831 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140245.1 1634459 D 264199 CDS YP_140246.2 161611277 3164684 1635147..1636169 1 NC_006448.1 NAD(P)+; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1636169 gpsA 3164684 gpsA Streptococcus thermophilus LMG 18311 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_140246.2 1635147 D 264199 CDS YP_140247.1 55821805 3164821 1636188..1637102 1 NC_006448.1 UDP-glucose pyrophosphorylase 1637102 galU 3164821 galU Streptococcus thermophilus LMG 18311 UDP-glucose pyrophosphorylase YP_140247.1 1636188 D 264199 CDS YP_140248.1 55821806 3164858 complement(1637165..1638034) 1 NC_006448.1 IS3 familytransposase orf2 1638034 tnpSth1 3164858 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf2 YP_140248.1 1637165 R 264199 CDS YP_140249.1 55821807 3164614 complement(1638049..1638789) 1 NC_006448.1 IS3 familytransposase orf1 1638789 tnpSth1 3164614 tnpSth1 Streptococcus thermophilus LMG 18311 IS3 familytransposase orf1 YP_140249.1 1638049 R 264199 CDS YP_140250.1 55821808 3164706 complement(1638835..1639509) 1 NC_006448.1 hypothetical protein 1639509 3164706 stu1836 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140250.1 1638835 R 264199 CDS YP_140251.1 55821809 3163877 complement(1639500..1640027) 1 NC_006448.1 hypothetical protein 1640027 3163877 stu1837 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140251.1 1639500 R 264199 CDS YP_140252.1 55821810 3164683 complement(1640096..1641229) 1 NC_006448.1 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 1641229 hipO3 3164683 hipO3 Streptococcus thermophilus LMG 18311 aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase YP_140252.1 1640096 R 264199 CDS YP_140253.1 55821811 3164799 complement(1641308..1642006) 1 NC_006448.1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1642006 dapD 3164799 dapD Streptococcus thermophilus LMG 18311 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_140253.1 1641308 R 264199 CDS YP_140254.1 55821812 3165121 complement(1642092..1642496) 1 NC_006448.1 truncated; hypothetical protein 1642496 3165121 stu1840 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140254.1 1642092 R 264199 CDS YP_140255.1 55821813 3165072 complement(1642490..1642861) 1 NC_006448.1 truncated; hypothetical protein 1642861 3165072 stu1841 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140255.1 1642490 R 264199 CDS YP_140256.1 55821814 3164323 complement(1642961..1643794) 1 NC_006448.1 rRNA (guanine-N1-)-methyltransferase 1643794 rrmA 3164323 rrmA Streptococcus thermophilus LMG 18311 rRNA (guanine-N1-)-methyltransferase YP_140256.1 1642961 R 264199 CDS YP_140257.1 55821815 3164031 1644163..1644330 1 NC_006448.1 hypothetical protein 1644330 3164031 stu1843 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140257.1 1644163 D 264199 CDS YP_140258.1 55821816 3163957 complement(1644727..1645245) 1 NC_006448.1 cytidine/deoxycytidylate deaminase family protein 1645245 3163957 stu1844 Streptococcus thermophilus LMG 18311 cytidine/deoxycytidylate deaminase family protein YP_140258.1 1644727 R 264199 CDS YP_140259.1 55821817 3163873 complement(1646005..1646397) 1 NC_006448.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1646397 ssbA 3163873 ssbA Streptococcus thermophilus LMG 18311 single-stranded DNA-binding protein YP_140259.1 1646005 R 264199 CDS YP_140260.1 55821818 3164048 complement(1646602..1646829) 1 NC_006448.1 transcriptional regulator 1646829 3164048 stu1846 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_140260.1 1646602 R 264199 CDS YP_140261.1 55821819 3165074 complement(1646844..1647875) 1 NC_006448.1 hypothetical protein 1647875 3165074 stu1847 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140261.1 1646844 R 264199 CDS YP_140262.1 55821820 3164112 complement(1648013..1648636) 1 NC_006448.1 phenylalanyl-tRNA synthetase-like protein 1648636 3164112 stu1848 Streptococcus thermophilus LMG 18311 phenylalanyl-tRNA synthetase-like protein YP_140262.1 1648013 R 264199 CDS YP_140263.1 55821821 3164959 complement(1648646..1648960) 1 NC_006448.1 thioredoxin 1648960 trxA2 3164959 trxA2 Streptococcus thermophilus LMG 18311 thioredoxin YP_140263.1 1648646 R 264199 CDS YP_140264.1 55821822 3164482 complement(1648957..1649250) 1 NC_006448.1 hypothetical protein 1649250 3164482 stu1850 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140264.1 1648957 R 264199 CDS YP_140265.1 55821823 3164288 1649341..1650408 1 NC_006448.1 glutamyl-aminopeptidase 1650408 pepA 3164288 pepA Streptococcus thermophilus LMG 18311 glutamyl-aminopeptidase YP_140265.1 1649341 D 264199 CDS YP_140266.1 55821824 3164788 1650424..1651194 1 NC_006448.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1651194 proC 3164788 proC Streptococcus thermophilus LMG 18311 pyrroline-5-carboxylate reductase YP_140266.1 1650424 D 264199 CDS YP_140267.1 55821825 3164889 complement(1651224..1651886) 1 NC_006448.1 hypothetical protein 1651886 3164889 stu1853 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140267.1 1651224 R 264199 CDS YP_140268.1 55821826 3164153 complement(1652108..1652437) 1 NC_006448.1 hypothetical protein 1652437 3164153 stu1854 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140268.1 1652108 R 264199 CDS YP_140269.1 55821827 3164680 complement(1652511..1652990) 1 NC_006448.1 truncated; hypothetical protein 1652990 3164680 stu1855 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140269.1 1652511 R 264199 CDS YP_140270.1 55821828 3163868 complement(1653179..1653388) 1 NC_006448.1 transcriptional regulator 1653388 3163868 stu1856 Streptococcus thermophilus LMG 18311 transcriptional regulator YP_140270.1 1653179 R 264199 CDS YP_140271.1 55821829 3164098 complement(1653625..1654845) 1 NC_006448.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1654845 ackA 3164098 ackA Streptococcus thermophilus LMG 18311 acetate kinase YP_140271.1 1653625 R 264199 CDS YP_140272.1 55821830 3164954 complement(1654874..1655830) 1 NC_006448.1 hypothetical protein 1655830 3164954 stu1858 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140272.1 1654874 R 264199 CDS YP_140273.1 55821831 3164380 complement(1655875..1656192) 1 NC_006448.1 hypothetical protein 1656192 3164380 stu1859 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140273.1 1655875 R 264199 CDS YP_140274.1 55821832 3164059 complement(1656170..1656631) 1 NC_006448.1 competence protein 1656631 3164059 stu1860 Streptococcus thermophilus LMG 18311 competence protein YP_140274.1 1656170 R 264199 CDS YP_140275.1 55821833 3163791 complement(1656591..1656884) 1 NC_006448.1 hypothetical protein 1656884 3163791 stu1861 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140275.1 1656591 R 264199 CDS YP_140276.1 55821834 3165112 complement(1656856..1657284) 1 NC_006448.1 competence protein 1657284 comGD 3165112 comGD Streptococcus thermophilus LMG 18311 competence protein YP_140276.1 1656856 R 264199 CDS YP_140277.1 55821835 3165113 complement(1657244..1657570) 1 NC_006448.1 late competence protein, exogenous DNA-binding protein 1657570 comGC 3165113 comGC Streptococcus thermophilus LMG 18311 late competence protein, exogenous DNA-binding protein YP_140277.1 1657244 R 264199 CDS YP_140278.1 55821836 3163968 complement(1657567..1658673) 1 NC_006448.1 late competence protein, ABC transporter subunit 1658673 comGB 3163968 comGB Streptococcus thermophilus LMG 18311 late competence protein, ABC transporter subunit YP_140278.1 1657567 R 264199 CDS YP_140279.1 55821837 3165134 complement(1658549..1659490) 1 NC_006448.1 late competence protein, ABC transporter subunit 1659490 comGA 3165134 comGA Streptococcus thermophilus LMG 18311 late competence protein, ABC transporter subunit YP_140279.1 1658549 R 264199 CDS YP_140280.1 55821838 3164324 complement(1659571..1659933) 1 NC_006448.1 hypothetical protein 1659933 3164324 stu1866 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140280.1 1659571 R 264199 CDS YP_140281.1 55821839 3164467 complement(1660092..1663730) 1 NC_006448.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1663730 rpoC 3164467 rpoC Streptococcus thermophilus LMG 18311 DNA-directed RNA polymerase subunit beta' YP_140281.1 1660092 R 264199 CDS YP_140282.1 55821840 3164337 complement(1663831..1667412) 1 NC_006448.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1667412 rpoB 3164337 rpoB Streptococcus thermophilus LMG 18311 DNA-directed RNA polymerase subunit beta YP_140282.1 1663831 R 264199 CDS YP_140283.1 55821841 3164638 complement(1667774..1670197) 1 NC_006448.1 penicillin-binding protein 1B 1670197 pbp1B 3164638 pbp1B Streptococcus thermophilus LMG 18311 penicillin-binding protein 1B YP_140283.1 1667774 R 264199 CDS YP_140284.1 55821842 3163872 1670239..1671555 1 NC_006448.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1671555 tyrS 3163872 tyrS Streptococcus thermophilus LMG 18311 tyrosyl-tRNA synthetase YP_140284.1 1670239 D 264199 CDS YP_140285.1 55821843 3164366 complement(1671681..1672703) 1 NC_006448.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1672703 ilvC 3164366 ilvC Streptococcus thermophilus LMG 18311 ketol-acid reductoisomerase YP_140285.1 1671681 R 264199 CDS YP_140286.1 55821844 3164934 complement(1672779..1673255) 1 NC_006448.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1673255 ilvH 3164934 ilvH Streptococcus thermophilus LMG 18311 acetolactate synthase 3 regulatory subunit YP_140286.1 1672779 R 264199 CDS YP_140287.1 55821845 3164762 complement(1673248..1674966) 1 NC_006448.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 1674966 ilvB 3164762 ilvB Streptococcus thermophilus LMG 18311 acetolactate synthase catalytic subunit YP_140287.1 1673248 R 264199 CDS YP_140288.1 55821846 3163855 complement(1675082..1676572) 1 NC_006448.1 truncated; dihydroxy-acid dehydratase, truncated 1676572 3163855 stu1874 Streptococcus thermophilus LMG 18311 dihydroxy-acid dehydratase, truncated YP_140288.1 1675082 R 264199 CDS YP_140289.1 55821847 3164559 complement(1676972..1678639) 1 NC_006448.1 hypothetical protein 1678639 3164559 stu1875 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140289.1 1676972 R 264199 CDS YP_140290.1 55821848 3164417 complement(1678639..1679004) 1 NC_006448.1 alkaline-shock protein 1679004 asp 3164417 asp Streptococcus thermophilus LMG 18311 alkaline-shock protein YP_140290.1 1678639 R 264199 CDS YP_140291.1 55821849 3164798 complement(1679114..1680403) 1 NC_006448.1 MATE family drug:Na+ antiporter 1680403 norN 3164798 norN Streptococcus thermophilus LMG 18311 MATE family drug:Na+ antiporter YP_140291.1 1679114 R 264199 CDS YP_140292.1 55821850 3164476 complement(1680461..1681945) 1 NC_006448.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1681945 thrC 3164476 thrC Streptococcus thermophilus LMG 18311 threonine synthase YP_140292.1 1680461 R 264199 CDS YP_140293.1 55821851 3165076 complement(1682624..1682941) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1682941 3165076 stu1879 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140293.1 1682624 R 264199 CDS YP_140294.1 55821852 3163842 complement(1682934..1683167) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1683167 3163842 stu1880 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140294.1 1682934 R 264199 CDS YP_140295.1 55821853 3164462 complement(1683151..1683597) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1683597 3164462 stu1881 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140295.1 1683151 R 264199 CDS YP_140296.1 55821854 3164571 complement(1683598..1684158) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1684158 3164571 stu1882 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140296.1 1683598 R 264199 CDS YP_140297.1 55821855 3164894 complement(1684155..1684427) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1684427 3164894 stu1883 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140297.1 1684155 R 264199 CDS YP_140298.1 55821856 3163760 complement(1684735..1685130) 1 NC_006448.1 truncated; alcohol-acetaldehyde dehydrogenase, truncated 1685130 3163760 stu1884 Streptococcus thermophilus LMG 18311 alcohol-acetaldehyde dehydrogenase, truncated YP_140298.1 1684735 R 264199 CDS YP_140299.1 55821857 3163809 complement(1685269..1687164) 1 NC_006448.1 endopeptidase O 1687164 pepO 3163809 pepO Streptococcus thermophilus LMG 18311 endopeptidase O YP_140299.1 1685269 R 264199 CDS YP_140300.1 55821858 3164503 complement(1687245..1687904) 1 NC_006448.1 truncated; trehalose-6-phosphate hydrolase, truncated 1687904 3164503 stu1886 Streptococcus thermophilus LMG 18311 trehalose-6-phosphate hydrolase, truncated YP_140300.1 1687245 R 264199 CDS YP_140301.1 55821859 3163748 complement(1687918..1688271) 1 NC_006448.1 truncated; trehalose-6-phosphate hydrolase, truncated 1688271 3163748 stu1887 Streptococcus thermophilus LMG 18311 trehalose-6-phosphate hydrolase, truncated YP_140301.1 1687918 R 264199 CDS YP_140302.1 55821860 3164867 complement(1688439..1688585) 1 NC_006448.1 truncated; trehalose-6-phosphate hydrolase, truncated 1688585 3164867 stu1888 Streptococcus thermophilus LMG 18311 trehalose-6-phosphate hydrolase, truncated YP_140302.1 1688439 R 264199 CDS YP_140303.1 55821861 3163917 complement(1688459..1688779) 1 NC_006448.1 truncated; trehalose PTS trehalose component IIBC, truncated 1688779 3163917 stu1889 Streptococcus thermophilus LMG 18311 trehalose PTS trehalose component IIBC, truncated YP_140303.1 1688459 R 264199 CDS YP_140304.1 55821862 3164595 complement(1688810..1689175) 1 NC_006448.1 truncated; trehalose PTS trehalose component IIBC, truncated 1689175 3164595 stu1890 Streptococcus thermophilus LMG 18311 trehalose PTS trehalose component IIBC, truncated YP_140304.1 1688810 R 264199 CDS YP_140305.1 55821863 3164812 complement(1689272..1689409) 1 NC_006448.1 truncated; trehalose PTS trehalose component IIBC, truncated 1689409 3164812 stu1891 Streptococcus thermophilus LMG 18311 trehalose PTS trehalose component IIBC, truncated YP_140305.1 1689272 R 264199 CDS YP_140306.1 55821864 3165117 1689521..1689679 1 NC_006448.1 truncated; trehalose operon transcriptional repressor 1689679 3165117 stu1892 Streptococcus thermophilus LMG 18311 trehalose operon transcriptional repressor YP_140306.1 1689521 D 264199 CDS YP_140307.1 55821865 3164675 1689734..1690231 1 NC_006448.1 truncated; trehalose operon transcriptional regulator truncated 1690231 3164675 stu1893 Streptococcus thermophilus LMG 18311 trehalose operon transcriptional regulator truncated YP_140307.1 1689734 D 264199 CDS YP_140308.1 55821866 3164250 complement(1690287..1690850) 1 NC_006448.1 hypothetical protein 1690850 3164250 stu1894 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140308.1 1690287 R 264199 CDS YP_140309.1 55821867 3164695 complement(1690860..1691198) 1 NC_006448.1 hypothetical protein 1691198 3164695 stu1895 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140309.1 1690860 R 264199 CDS YP_140310.1 55821868 3164883 complement(1691231..1691587) 1 NC_006448.1 hypothetical protein 1691587 3164883 stu1896 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140310.1 1691231 R 264199 CDS YP_140312.1 55821870 3163892 1692168..1692623 1 NC_006448.1 truncated; hypothetical protein 1692623 3163892 stu1898 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140312.1 1692168 D 264199 CDS YP_140313.1 55821871 3163937 complement(1692898..1693779) 1 NC_006448.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1693779 fba 3163937 fba Streptococcus thermophilus LMG 18311 fructose-bisphosphate aldolase YP_140313.1 1692898 R 264199 CDS YP_140314.1 55821872 3165164 complement(1694198..1694803) 1 NC_006448.1 truncated; glutamate--cysteine ligase, truncated 1694803 3165164 stu1900 Streptococcus thermophilus LMG 18311 glutamate--cysteine ligase, truncated YP_140314.1 1694198 R 264199 CDS YP_140315.1 55821873 3163773 complement(1694861..1695049) 1 NC_006448.1 truncated; glutamate--cysteine ligase, truncated 1695049 3163773 stu1901 Streptococcus thermophilus LMG 18311 glutamate--cysteine ligase, truncated YP_140315.1 1694861 R 264199 CDS YP_140316.1 55821874 3164967 complement(1695110..1695256) 1 NC_006448.1 truncated; glutamate--cysteine ligase, truncated 1695256 3164967 stu1902 Streptococcus thermophilus LMG 18311 glutamate--cysteine ligase, truncated YP_140316.1 1695110 R 264199 CDS YP_140317.1 55821875 3164678 complement(1695353..1695538) 1 NC_006448.1 truncated; glutamate--cysteine ligase, truncated 1695538 3164678 stu1903 Streptococcus thermophilus LMG 18311 glutamate--cysteine ligase, truncated YP_140317.1 1695353 R 264199 CDS YP_140318.1 55821876 3164784 1695618..1695773 1 NC_006448.1 truncated; hypothetical protein 1695773 3164784 stu1904 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140318.1 1695618 D 264199 CDS YP_140319.1 55821877 3163750 1695965..1696420 1 NC_006448.1 truncated; hypothetical protein 1696420 3163750 stu1905 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140319.1 1695965 D 264199 CDS YP_140320.1 55821878 3163900 complement(1696835..1697221) 1 NC_006448.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1697221 rplQ 3163900 rplQ Streptococcus thermophilus LMG 18311 50S ribosomal protein L17 YP_140320.1 1696835 R 264199 CDS YP_140321.1 55821879 3163927 complement(1697239..1698177) 1 NC_006448.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1698177 rpoA 3163927 rpoA Streptococcus thermophilus LMG 18311 DNA-directed RNA polymerase subunit alpha YP_140321.1 1697239 R 264199 CDS YP_140322.1 55821880 3164870 complement(1698226..1698609) 1 NC_006448.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1698609 rpsK 3164870 rpsK Streptococcus thermophilus LMG 18311 30S ribosomal protein S11 YP_140322.1 1698226 R 264199 CDS YP_140323.1 55821881 3164873 complement(1698637..1699002) 1 NC_006448.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1699002 rpsM 3164873 rpsM Streptococcus thermophilus LMG 18311 30S ribosomal protein S13 YP_140323.1 1698637 R 264199 CDS YP_140324.1 55821882 3163743 complement(1699020..1699136) 1 NC_006448.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1699136 rpmJ 3163743 rpmJ Streptococcus thermophilus LMG 18311 50S ribosomal protein L36 YP_140324.1 1699020 R 264199 CDS YP_140325.1 55821883 3164535 complement(1699162..1699380) 1 NC_006448.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1699380 infA 3164535 infA Streptococcus thermophilus LMG 18311 translation initiation factor IF-1 YP_140325.1 1699162 R 264199 CDS YP_140326.1 55821884 3164234 complement(1699498..1700154) 1 NC_006448.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1700154 adk 3164234 adk Streptococcus thermophilus LMG 18311 adenylate kinase YP_140326.1 1699498 R 264199 CDS YP_140327.1 55821885 3163910 complement(1700286..1701581) 1 NC_006448.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1701581 secY 3163910 secY Streptococcus thermophilus LMG 18311 preprotein translocase subunit SecY YP_140327.1 1700286 R 264199 CDS YP_140328.2 161611276 3164654 complement(1701598..1702038) 1 NC_006448.1 late assembly protein; 50S ribosomal protein L15 1702038 rplO 3164654 rplO Streptococcus thermophilus LMG 18311 50S ribosomal protein L15 YP_140328.2 1701598 R 264199 CDS YP_140329.1 55821887 3164707 complement(1702166..1702348) 1 NC_006448.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1702348 rpmD 3164707 rpmD Streptococcus thermophilus LMG 18311 50S ribosomal protein L30 YP_140329.1 1702166 R 264199 CDS YP_140330.1 55821888 3165166 complement(1702363..1702857) 1 NC_006448.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1702857 rpsE 3165166 rpsE Streptococcus thermophilus LMG 18311 30S ribosomal protein S5 YP_140330.1 1702363 R 264199 CDS YP_140331.2 161611275 3164091 complement(1702876..1703232) 1 NC_006448.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1703232 rplR 3164091 rplR Streptococcus thermophilus LMG 18311 50S ribosomal protein L18 YP_140331.2 1702876 R 264199 CDS YP_140332.1 55821890 3164598 complement(1703322..1703858) 1 NC_006448.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1703858 rplF 3164598 rplF Streptococcus thermophilus LMG 18311 50S ribosomal protein L6 YP_140332.1 1703322 R 264199 CDS YP_140333.1 55821891 3164579 complement(1703985..1704383) 1 NC_006448.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1704383 rpsH 3164579 rpsH Streptococcus thermophilus LMG 18311 30S ribosomal protein S8 YP_140333.1 1703985 R 264199 CDS YP_140334.1 55821892 3164315 complement(1704506..1704691) 1 NC_006448.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1704691 rpsN 3164315 rpsN Streptococcus thermophilus LMG 18311 30S ribosomal protein S14 YP_140334.1 1704506 R 264199 CDS YP_140335.1 55821893 3165080 complement(1704709..1705251) 1 NC_006448.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1705251 rplE 3165080 rplE Streptococcus thermophilus LMG 18311 50S ribosomal protein L5 YP_140335.1 1704709 R 264199 CDS YP_140336.1 55821894 3164971 complement(1705278..1705583) 1 NC_006448.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1705583 rplX 3164971 rplX Streptococcus thermophilus LMG 18311 50S ribosomal protein L24 YP_140336.1 1705278 R 264199 CDS YP_140337.1 55821895 3164956 complement(1705664..1706032) 1 NC_006448.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1706032 rplN 3164956 rplN Streptococcus thermophilus LMG 18311 50S ribosomal protein L14 YP_140337.1 1705664 R 264199 CDS YP_140338.1 55821896 3163789 complement(1706057..1706317) 1 NC_006448.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1706317 rpsQ 3163789 rpsQ Streptococcus thermophilus LMG 18311 30S ribosomal protein S17 YP_140338.1 1706057 R 264199 CDS YP_140339.1 55821897 3164166 complement(1706345..1706551) 1 NC_006448.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1706551 rpmC 3164166 rpmC Streptococcus thermophilus LMG 18311 50S ribosomal protein L29 YP_140339.1 1706345 R 264199 CDS YP_140340.1 55821898 3163796 complement(1706561..1706974) 1 NC_006448.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1706974 rplP 3163796 rplP Streptococcus thermophilus LMG 18311 50S ribosomal protein L16 YP_140340.1 1706561 R 264199 CDS YP_140341.1 55821899 3164070 complement(1706978..1707631) 1 NC_006448.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1707631 rpsC 3164070 rpsC Streptococcus thermophilus LMG 18311 30S ribosomal protein S3 YP_140341.1 1706978 R 264199 CDS YP_140342.1 55821900 3164781 complement(1707644..1707988) 1 NC_006448.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1707988 rplV 3164781 rplV Streptococcus thermophilus LMG 18311 50S ribosomal protein L22 YP_140342.1 1707644 R 264199 CDS YP_140343.1 55821901 3164232 complement(1708004..1708282) 1 NC_006448.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1708282 rpsS 3164232 rpsS Streptococcus thermophilus LMG 18311 30S ribosomal protein S19 YP_140343.1 1708004 R 264199 CDS YP_140344.1 55821902 3163909 complement(1708376..1709209) 1 NC_006448.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1709209 rplB 3163909 rplB Streptococcus thermophilus LMG 18311 50S ribosomal protein L2 YP_140344.1 1708376 R 264199 CDS YP_140345.1 55821903 3165115 complement(1709227..1709523) 1 NC_006448.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1709523 rplW 3165115 rplW Streptococcus thermophilus LMG 18311 50S ribosomal protein L23 YP_140345.1 1709227 R 264199 CDS YP_140346.1 55821904 3163802 complement(1709523..1710146) 1 NC_006448.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1710146 rplD 3163802 rplD Streptococcus thermophilus LMG 18311 50S ribosomal protein L4 YP_140346.1 1709523 R 264199 CDS YP_140347.1 55821905 3164301 complement(1710171..1710797) 1 NC_006448.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1710797 rplC 3164301 rplC Streptococcus thermophilus LMG 18311 50S ribosomal protein L3 YP_140347.1 1710171 R 264199 CDS YP_140348.1 55821906 3164739 complement(1710914..1711222) 1 NC_006448.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1711222 rpsJ 3164739 rpsJ Streptococcus thermophilus LMG 18311 30S ribosomal protein S10 YP_140348.1 1710914 R 264199 CDS YP_140349.1 55821907 3163844 complement(1711466..1712467) 1 NC_006448.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1712467 ruvB 3163844 ruvB Streptococcus thermophilus LMG 18311 Holliday junction DNA helicase RuvB YP_140349.1 1711466 R 264199 CDS YP_140350.1 55821908 3164658 complement(1712548..1714371) 1 NC_006448.1 hypothetical protein 1714371 3164658 stu1937 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140350.1 1712548 R 264199 CDS YP_140351.1 55821909 3165145 complement(1714368..1714778) 1 NC_006448.1 hypothetical protein 1714778 3165145 stu1938 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140351.1 1714368 R 264199 CDS YP_140352.1 55821910 3164118 complement(1714775..1715209) 1 NC_006448.1 protein-tyrosine-phosphatase 1715209 3164118 stu1939 Streptococcus thermophilus LMG 18311 protein-tyrosine-phosphatase YP_140352.1 1714775 R 264199 CDS YP_140353.1 55821911 3164073 complement(1715491..1716783) 1 NC_006448.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1716783 purA 3164073 purA Streptococcus thermophilus LMG 18311 adenylosuccinate synthetase YP_140353.1 1715491 R 264199 CDS YP_140354.1 55821912 3165005 complement(1717037..1717552) 1 NC_006448.1 topology modulation protein 1717552 flaR 3165005 flaR Streptococcus thermophilus LMG 18311 topology modulation protein YP_140354.1 1717037 R 264199 CDS YP_140355.1 55821913 3164344 1717892..1719097 1 NC_006448.1 hypothetical protein 1719097 3164344 stu1942 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140355.1 1717892 D 264199 CDS YP_140356.1 55821914 3164373 complement(1719293..1720501) 1 NC_006448.1 IS1191 transposase 1720501 tnp1191 3164373 tnp1191 Streptococcus thermophilus LMG 18311 IS1191 transposase YP_140356.1 1719293 R 264199 CDS YP_140357.1 55821915 3165186 1720872..1721765 1 NC_006448.1 MutR family transcriptional regulator 1721765 3165186 stu1947 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator YP_140357.1 1720872 D 264199 CDS YP_140358.1 55821916 3165148 1721850..1724009 1 NC_006448.1 hypothetical protein 1724009 3165148 stu1948 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140358.1 1721850 D 264199 CDS YP_140359.1 55821917 3164543 1724014..1725582 1 NC_006448.1 micrococin J25 ABC exporter ATP binding/membrane protein 1725582 3164543 stu1949 Streptococcus thermophilus LMG 18311 micrococin J25 ABC exporter ATP binding/membrane protein YP_140359.1 1724014 D 264199 CDS YP_140360.1 55821918 3165063 1726501..1727199 1 NC_006448.1 truncated; MutR family transcriptional regulator, truncated 1727199 3165063 stu1950 Streptococcus thermophilus LMG 18311 MutR family transcriptional regulator, truncated YP_140360.1 1726501 D 264199 CDS YP_140361.1 55821919 3164121 1727366..1728640 1 NC_006448.1 hypothetical protein 1728640 3164121 stu1951 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140361.1 1727366 D 264199 CDS YP_140362.1 55821920 3164165 1728633..1730174 1 NC_006448.1 ABC exporter ATP binding/membrane-spanning protein 1730174 3164165 stu1952 Streptococcus thermophilus LMG 18311 ABC exporter ATP binding/membrane-spanning protein YP_140362.1 1728633 D 264199 CDS YP_140363.1 55821921 3165058 1730568..1731545 1 NC_006448.1 replication initiator protein 1731545 rip 3165058 rip Streptococcus thermophilus LMG 18311 replication initiator protein YP_140363.1 1730568 D 264199 CDS YP_140364.1 55821922 3164813 1731557..1731745 1 NC_006448.1 hypothetical protein 1731745 3164813 stu1954 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140364.1 1731557 D 264199 CDS YP_140365.1 55821923 3164092 1731747..1732886 1 NC_006448.1 integrase/recombinase 1732886 int 3164092 int Streptococcus thermophilus LMG 18311 integrase/recombinase YP_140365.1 1731747 D 264199 CDS YP_140366.1 55821924 3163798 complement(1733329..1734597) 1 NC_006448.1 recombination factor protein RarA 1734597 cshA 3163798 cshA Streptococcus thermophilus LMG 18311 recombination factor protein RarA YP_140366.1 1733329 R 264199 CDS YP_140367.1 55821925 3164785 1734768..1734956 1 NC_006448.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1734956 rpmB 3164785 rpmB Streptococcus thermophilus LMG 18311 50S ribosomal protein L28 YP_140367.1 1734768 D 264199 CDS YP_140368.1 55821926 3164724 1735083..1735349 1 NC_006448.1 hypothetical protein 1735349 3164724 stu1959 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140368.1 1735083 D 264199 CDS YP_140369.1 55821927 3164179 1735349..1735768 1 NC_006448.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1735768 3164179 stu1960 Streptococcus thermophilus LMG 18311 Holliday junction resolvase-like protein YP_140369.1 1735349 D 264199 CDS YP_140370.1 55821928 3165062 1735847..1736182 1 NC_006448.1 hypothetical protein 1736182 3165062 stu1961 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140370.1 1735847 D 264199 CDS YP_140371.1 55821929 3164508 1736395..1738041 1 NC_006448.1 hypothetical protein 1738041 3164508 stu1962 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140371.1 1736395 D 264199 CDS YP_140372.1 55821930 3164442 1738151..1740355 1 NC_006448.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1740355 nrdD 3164442 nrdD Streptococcus thermophilus LMG 18311 anaerobic ribonucleoside triphosphate reductase YP_140372.1 1738151 D 264199 CDS YP_140373.1 55821931 3164093 1740457..1740588 1 NC_006448.1 hypothetical protein 1740588 3164093 stu1964 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140373.1 1740457 D 264199 CDS YP_140374.1 55821932 3164039 1740590..1741090 1 NC_006448.1 acetyltransferase 1741090 3164039 stu1965 Streptococcus thermophilus LMG 18311 acetyltransferase YP_140374.1 1740590 D 264199 CDS YP_140375.1 55821933 3165001 1741095..1741700 1 NC_006448.1 anaerobic ribonucleotide reductase activator 1741700 nrdG 3165001 nrdG Streptococcus thermophilus LMG 18311 anaerobic ribonucleotide reductase activator YP_140375.1 1741095 D 264199 CDS YP_140376.1 55821934 3164173 complement(1741722..1742489) 1 NC_006448.1 hypothetical protein 1742489 3164173 stu1967 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140376.1 1741722 R 264199 CDS YP_140377.1 55821935 3164284 complement(1742549..1743490) 1 NC_006448.1 hypothetical protein 1743490 3164284 stu1968 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140377.1 1742549 R 264199 CDS YP_140378.1 55821936 3164517 complement(1743483..1745234) 1 NC_006448.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1745234 aspS 3164517 aspS Streptococcus thermophilus LMG 18311 aspartyl-tRNA synthetase YP_140378.1 1743483 R 264199 CDS YP_140379.1 55821937 3164819 complement(1745344..1745766) 1 NC_006448.1 hypothetical protein 1745766 3164819 stu1970 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140379.1 1745344 R 264199 CDS YP_140380.1 55821938 3163860 complement(1745774..1747054) 1 NC_006448.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1747054 hisS 3163860 hisS Streptococcus thermophilus LMG 18311 histidyl-tRNA synthetase YP_140380.1 1745774 R 264199 CDS YP_140381.1 55821939 3164965 complement(1747364..1748122) 1 NC_006448.1 truncated; hypothetical protein 1748122 3164965 stu1972 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140381.1 1747364 R 264199 CDS YP_140382.1 55821940 3164558 complement(1748270..1748497) 1 NC_006448.1 truncated; hypothetical protein 1748497 3164558 stu1973 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140382.1 1748270 R 264199 CDS YP_140383.1 55821941 3164554 1748727..1748909 1 NC_006448.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1748909 rpmF 3164554 rpmF Streptococcus thermophilus LMG 18311 50S ribosomal protein L32 YP_140383.1 1748727 D 264199 CDS YP_140384.1 55821942 3164997 1748925..1749074 1 NC_006448.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1749074 rpmG 3164997 rpmG Streptococcus thermophilus LMG 18311 50S ribosomal protein L33 YP_140384.1 1748925 D 264199 CDS YP_140385.1 55821943 3164465 complement(1749295..1749528) 1 NC_006448.1 hypothetical protein 1749528 3164465 stu1976 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140385.1 1749295 R 264199 CDS YP_140386.1 55821944 3163867 complement(1749528..1749782) 1 NC_006448.1 hypothetical protein 1749782 3163867 stu1977 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140386.1 1749528 R 264199 CDS YP_140387.1 55821945 3163838 complement(1749841..1750020) 1 NC_006448.1 truncated; hypothetical protein 1750020 3163838 stu1978 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140387.1 1749841 R 264199 CDS YP_140388.1 55821946 3164010 complement(1750408..1750722) 1 NC_006448.1 truncated; hypothetical protein 1750722 3164010 stu1979 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140388.1 1750408 R 264199 CDS YP_140389.1 55821947 3163876 complement(1751068..1751658) 1 NC_006448.1 truncated; hypothetical protein 1751658 3163876 stu1980 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140389.1 1751068 R 264199 CDS YP_140390.1 55821948 3164006 complement(1751714..1752085) 1 NC_006448.1 hypothetical protein 1752085 3164006 stu1981 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140390.1 1751714 R 264199 CDS YP_140391.1 55821949 3164749 1752674..1752913 1 NC_006448.1 hypothetical protein 1752913 3164749 stu1982 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140391.1 1752674 D 264199 CDS YP_140392.1 55821950 3164520 1752972..1753538 1 NC_006448.1 hypothetical protein 1753538 3164520 stu1983 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140392.1 1752972 D 264199 CDS YP_140393.1 55821951 3164911 1753551..1753721 1 NC_006448.1 hypothetical protein 1753721 3164911 stu1984 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140393.1 1753551 D 264199 CDS YP_140394.1 55821952 3163755 complement(1753765..1754805) 1 NC_006448.1 IS1239 transposase 1754805 tnp1239 3163755 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_140394.1 1753765 R 264199 CDS YP_140395.1 55821953 3163903 1754980..1755537 1 NC_006448.1 hypothetical protein 1755537 3163903 stu1986 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140395.1 1754980 D 264199 CDS YP_140396.1 55821954 3164005 1755610..1755813 1 NC_006448.1 hypothetical protein 1755813 3164005 stu1987 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140396.1 1755610 D 264199 CDS YP_140397.1 55821955 3164576 complement(1756405..1756956) 1 NC_006448.1 hypothetical protein 1756956 3164576 stu1988 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140397.1 1756405 R 264199 CDS YP_140398.1 55821956 3164494 1757243..1757395 1 NC_006448.1 truncated; hypothetical protein 1757395 3164494 stu1989 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140398.1 1757243 D 264199 CDS YP_140399.1 55821957 3163837 1757409..1757570 1 NC_006448.1 truncated; hypothetical protein 1757570 3163837 stu1990 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140399.1 1757409 D 264199 CDS YP_140400.1 55821958 3164363 1757776..1757997 1 NC_006448.1 hypothetical protein 1757997 3164363 stu1991 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140400.1 1757776 D 264199 CDS YP_140401.1 55821959 3165195 1758111..1758986 1 NC_006448.1 hypothetical protein 1758986 3165195 stu1992 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140401.1 1758111 D 264199 CDS YP_140402.1 55821960 3164181 complement(1759023..1761155) 1 NC_006448.1 truncated; hypothetical protein 1761155 3164181 stu1993 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140402.1 1759023 R 264199 CDS YP_140403.1 55821961 3163994 complement(1761133..1761393) 1 NC_006448.1 truncated; hypothetical protein 1761393 3163994 stu1994 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140403.1 1761133 R 264199 CDS YP_140404.1 55821962 3163803 1761522..1762061 1 NC_006448.1 TetR/AcrR family transcriptional regulator 1762061 3163803 stu1995 Streptococcus thermophilus LMG 18311 TetR/AcrR family transcriptional regulator YP_140404.1 1761522 D 264199 CDS YP_140405.1 55821963 3164123 complement(1762139..1762501) 1 NC_006448.1 hypothetical protein 1762501 3164123 stu1996 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140405.1 1762139 R 264199 CDS YP_140406.1 55821964 3164407 complement(1763032..1763685) 1 NC_006448.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1763685 rpsD 3164407 rpsD Streptococcus thermophilus LMG 18311 30S ribosomal protein S4 YP_140406.1 1763032 R 264199 CDS YP_140407.1 55821965 3164522 complement(1763841..1764143) 1 NC_006448.1 hypothetical protein 1764143 3164522 stu1998 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140407.1 1763841 R 264199 CDS YP_140408.1 55821966 3163995 complement(1764167..1765528) 1 NC_006448.1 unwinds double stranded DNA; replicative DNA helicase 1765528 holB 3163995 holB Streptococcus thermophilus LMG 18311 replicative DNA helicase YP_140408.1 1764167 R 264199 CDS YP_140409.2 161611274 3164697 complement(1765572..1766030) 1 NC_006448.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1766030 rplI 3164697 rplI Streptococcus thermophilus LMG 18311 50S ribosomal protein L9 YP_140409.2 1765572 R 264199 CDS YP_140410.1 55821968 3163959 complement(1766032..1767996) 1 NC_006448.1 hypothetical protein 1767996 3163959 stu2001 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140410.1 1766032 R 264199 CDS YP_140411.1 55821969 3164766 complement(1768070..1770073) 1 NC_006448.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1770073 gidA 3164766 gidA Streptococcus thermophilus LMG 18311 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_140411.1 1768070 R 264199 CDS YP_140412.1 55821970 3164493 complement(1770246..1771367) 1 NC_006448.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1771367 mnmA 3164493 mnmA Streptococcus thermophilus LMG 18311 tRNA-specific 2-thiouridylase MnmA YP_140412.1 1770246 R 264199 CDS YP_140413.1 55821971 3165092 complement(1771506..1773236) 1 NC_006448.1 hypothetical protein 1773236 3165092 stu2004 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140413.1 1771506 R 264199 CDS YP_140414.1 55821972 3164489 complement(1773323..1773952) 1 NC_006448.1 hypothetical protein 1773952 3164489 stu2005 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140414.1 1773323 R 264199 CDS YP_140415.1 55821973 3165083 complement(1774193..1774747) 1 NC_006448.1 hypothetical protein 1774747 3165083 stu2006 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140415.1 1774193 R 264199 CDS YP_140416.1 55821974 3164778 complement(1775051..1775845) 1 NC_006448.1 ABC transporter membrane-spanning protein 1775845 3164778 stu2007 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_140416.1 1775051 R 264199 CDS YP_140417.1 55821975 3164807 complement(1775838..1776680) 1 NC_006448.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 1776680 cbiO 3164807 cbiO Streptococcus thermophilus LMG 18311 cobalt transporter ATP-binding subunit YP_140417.1 1775838 R 264199 CDS YP_140418.1 55821976 3164453 complement(1776656..1777486) 1 NC_006448.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 1777486 cbiO 3164453 cbiO Streptococcus thermophilus LMG 18311 cobalt transporter ATP-binding subunit YP_140418.1 1776656 R 264199 CDS YP_140419.1 55821977 3164538 complement(1777499..1778041) 1 NC_006448.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1778041 pgsA 3164538 pgsA Streptococcus thermophilus LMG 18311 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_140419.1 1777499 R 264199 CDS YP_140420.1 55821978 3164083 complement(1778054..1778911) 1 NC_006448.1 hypothetical protein 1778911 3164083 stu2011 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140420.1 1778054 R 264199 CDS YP_140421.1 55821979 3164253 complement(1778970..1780247) 1 NC_006448.1 peptidase 1780247 3164253 stu2012 Streptococcus thermophilus LMG 18311 peptidase YP_140421.1 1778970 R 264199 CDS YP_140422.1 55821980 3165588 complement(1780249..1781499) 1 NC_006448.1 protease 1781499 3165588 stu2013 Streptococcus thermophilus LMG 18311 protease YP_140422.1 1780249 R 264199 CDS YP_140423.1 55821981 3163990 1781577..1781954 1 NC_006448.1 hypothetical protein 1781954 3163990 stu2014 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140423.1 1781577 D 264199 CDS YP_140424.1 55821982 3164279 1781957..1783057 1 NC_006448.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1783057 recF 3164279 recF Streptococcus thermophilus LMG 18311 recombination protein F YP_140424.1 1781957 D 264199 CDS YP_140425.1 55821983 3165149 complement(1783226..1784707) 1 NC_006448.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1784707 guaB 3165149 guaB Streptococcus thermophilus LMG 18311 inosine 5'-monophosphate dehydrogenase YP_140425.1 1783226 R 264199 CDS YP_140426.1 55821984 3164688 1785019..1786059 1 NC_006448.1 IS1239 transposase 1786059 tnp1239 3164688 tnp1239 Streptococcus thermophilus LMG 18311 IS1239 transposase YP_140426.1 1785019 D 264199 CDS YP_140427.1 55821985 3165438 complement(1786129..1787151) 1 NC_006448.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1787151 trpS 3165438 trpS Streptococcus thermophilus LMG 18311 tryptophanyl-tRNA synthetase YP_140427.1 1786129 R 264199 CDS YP_140428.1 55821986 3164362 1788017..1788451 1 NC_006448.1 truncated; hypothetical protein 1788451 3164362 stu2019 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140428.1 1788017 D 264199 CDS YP_140429.1 55821987 3164080 1788518..1790140 1 NC_006448.1 ABC transporter ATP-binding protein 1790140 3164080 stu2020 Streptococcus thermophilus LMG 18311 ABC transporter ATP-binding protein YP_140429.1 1788518 D 264199 CDS YP_140430.1 55821988 3164519 1790190..1792796 1 NC_006448.1 ABC transporter membrane-spanning protein 1792796 3164519 stu2021 Streptococcus thermophilus LMG 18311 ABC transporter membrane-spanning protein YP_140430.1 1790190 D 264199 CDS YP_140431.1 55821989 3163793 complement(1793341..1794024) 1 NC_006448.1 hypothetical protein 1794024 3163793 stu2022 Streptococcus thermophilus LMG 18311 hypothetical protein YP_140431.1 1793341 R 264199 CDS YP_140432.2 229221135 3164694 complement(1794040..1794519) 1 NC_006448.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1794519 3164694 stu2023 Streptococcus thermophilus LMG 18311 rRNA large subunit methyltransferase YP_140432.2 1794040 R 264199 CDS YP_140433.1 55821991 3165096 1794724..1795959 1 NC_006448.1 exported serine protease 1795959 htrA 3165096 htrA Streptococcus thermophilus LMG 18311 exported serine protease YP_140433.1 1794724 D 264199 CDS YP_140434.1 55821992 3163797 1796025..1796792 1 NC_006448.1 chromosome segregation protein 1796792 spoJ 3163797 spoJ Streptococcus thermophilus LMG 18311 chromosome segregation protein YP_140434.1 1796025 D 264199 CDS