-- dump date 20120504_163113 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 264199000001 SEQ_END SEQ_END NC_006448.1 1796846 1796846 DR NC_006448.1; contig end 1796846..1796846 Streptococcus thermophilus LMG 18311 YP_138546.1 CDS dnaA NC_006448.1 186 1550 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 186..1550 Streptococcus thermophilus LMG 18311 3164689 YP_138547.1 CDS dnaN NC_006448.1 1705 2841 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1705..2841 Streptococcus thermophilus LMG 18311 3164740 YP_138548.1 CDS stu0003 NC_006448.1 2892 3083 D hypothetical protein 2892..3083 Streptococcus thermophilus LMG 18311 3164987 YP_138549.1 CDS stu0004 NC_006448.1 3296 4411 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3296..4411 Streptococcus thermophilus LMG 18311 3164481 YP_138550.1 CDS pth NC_006448.1 4484 5053 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4484..5053 Streptococcus thermophilus LMG 18311 3164040 YP_138551.1 CDS trcF NC_006448.1 5046 8552 D transcription repair coupling factor 5046..8552 Streptococcus thermophilus LMG 18311 3164963 YP_138552.1 CDS stu0007 NC_006448.1 8738 9013 D hypothetical protein 8738..9013 Streptococcus thermophilus LMG 18311 3163979 YP_138553.1 CDS divIC NC_006448.1 8997 9368 D MesJ/Ycf62 family cell-cycle protein 8997..9368 Streptococcus thermophilus LMG 18311 3164575 YP_138554.1 CDS stu0009 NC_006448.1 9496 10788 D hypothetical protein 9496..10788 Streptococcus thermophilus LMG 18311 3164993 YP_138555.1 CDS stu0010 NC_006448.1 10788 12053 D cell-cycle protein MesJ/Ycf62 family 10788..12053 Streptococcus thermophilus LMG 18311 3164886 YP_138556.1 CDS hpt NC_006448.1 12135 12677 D Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 12135..12677 Streptococcus thermophilus LMG 18311 3163932 YP_138557.1 CDS ftsH NC_006448.1 12693 14660 D cell division protein 12693..14660 Streptococcus thermophilus LMG 18311 3163906 YP_138558.1 CDS stu0013 NC_006448.1 14678 14899 R truncated; hypothetical protein complement(14678..14899) Streptococcus thermophilus LMG 18311 3163841 YP_138559.1 CDS stu0014 NC_006448.1 14978 15703 R truncated; hypothetical protein complement(14978..15703) Streptococcus thermophilus LMG 18311 3163827 YP_138560.1 CDS stu0015 NC_006448.1 15621 15905 R truncated; hypothetical protein complement(15621..15905) Streptococcus thermophilus LMG 18311 3165158 YP_138561.1 CDS stu0016 NC_006448.1 15986 16246 D truncated; hypothetical protein 15986..16246 Streptococcus thermophilus LMG 18311 3164499 YP_138562.1 CDS stu0017 NC_006448.1 16446 16601 D truncated; hypothetical protein 16446..16601 Streptococcus thermophilus LMG 18311 3165109 YP_138563.1 CDS stu0018 NC_006448.1 16577 16915 D truncated; hypothetical protein 16577..16915 Streptococcus thermophilus LMG 18311 3163901 YP_138564.1 CDS stu0019 NC_006448.1 16929 17417 D truncated; hypothetical protein 16929..17417 Streptococcus thermophilus LMG 18311 3164065 YP_138565.1 CDS mreC NC_006448.1 24270 25100 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 24270..25100 Streptococcus thermophilus LMG 18311 3164850 YP_138566.1 CDS mreD NC_006448.1 25048 25626 D rod shape-determining protein MreD 25048..25626 Streptococcus thermophilus LMG 18311 3164750 YP_138567.1 CDS pcsB NC_006448.1 25711 27135 D glucan binding protein 25711..27135 Streptococcus thermophilus LMG 18311 3163816 YP_138568.1 CDS prsA1 NC_006448.1 27337 28314 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 27337..28314 Streptococcus thermophilus LMG 18311 3163850 YP_138569.1 CDS stu0024 NC_006448.1 28393 28659 R truncated; truncated IS1193 transposase complement(28393..28659) Streptococcus thermophilus LMG 18311 3164437 YP_138570.1 CDS stu0025 NC_006448.1 28782 29048 R truncated; truncated IS1193 transposase complement(28782..29048) Streptococcus thermophilus LMG 18311 3163762 YP_138571.1 CDS araT NC_006448.1 29414 30598 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 29414..30598 Streptococcus thermophilus LMG 18311 3164061 YP_138572.1 CDS recO NC_006448.1 30585 31358 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 30585..31358 Streptococcus thermophilus LMG 18311 3165561 YP_138573.1 CDS plsX NC_006448.1 31574 32578 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 31574..32578 Streptococcus thermophilus LMG 18311 3164394 YP_138574.1 CDS acpP1 NC_006448.1 32578 32823 D acyl carrier protein 32578..32823 Streptococcus thermophilus LMG 18311 3164316 YP_138575.1 CDS purC NC_006448.1 33109 33816 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 33109..33816 Streptococcus thermophilus LMG 18311 3164319 YP_138576.1 CDS purL NC_006448.1 33848 37597 D phosphoribosylformylglycinamidine synthase II 33848..37597 Streptococcus thermophilus LMG 18311 3164480 YP_138577.1 CDS purF NC_006448.1 37766 39205 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 37766..39205 Streptococcus thermophilus LMG 18311 3164619 YP_138578.1 CDS purM NC_006448.1 39236 40255 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 39236..40255 Streptococcus thermophilus LMG 18311 3163831 YP_138579.1 CDS purN NC_006448.1 40255 40809 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 40255..40809 Streptococcus thermophilus LMG 18311 3165077 YP_138580.1 CDS purH NC_006448.1 40827 42425 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 40827..42425 Streptococcus thermophilus LMG 18311 3163856 YP_138581.1 CDS stu0036 NC_006448.1 42596 43054 D truncated; hypothetical protein 42596..43054 Streptococcus thermophilus LMG 18311 3163786 YP_138582.1 CDS stu0037 NC_006448.1 43108 43422 D truncated; hypothetical protein 43108..43422 Streptococcus thermophilus LMG 18311 3164637 YP_138583.1 CDS stu0038 NC_006448.1 43472 43717 D truncated; hypothetical protein 43472..43717 Streptococcus thermophilus LMG 18311 3164926 YP_138584.1 CDS cbpD1 NC_006448.1 43821 44660 R cell wall protein, choline binding protein complement(43821..44660) Streptococcus thermophilus LMG 18311 3164132 YP_138585.1 CDS purD NC_006448.1 44968 46230 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 44968..46230 Streptococcus thermophilus LMG 18311 3164075 YP_138586.1 CDS purE NC_006448.1 46564 47064 D Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 46564..47064 Streptococcus thermophilus LMG 18311 3164268 YP_138587.1 CDS purK NC_006448.1 47051 48142 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 47051..48142 Streptococcus thermophilus LMG 18311 3165193 YP_138588.1 CDS stu0043 NC_006448.1 48335 49090 D hypothetical protein 48335..49090 Streptococcus thermophilus LMG 18311 3164194 YP_138589.1 CDS stu0044 NC_006448.1 49162 49326 D hypothetical protein 49162..49326 Streptococcus thermophilus LMG 18311 3164410 YP_138590.1 CDS purB NC_006448.1 49605 50903 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 49605..50903 Streptococcus thermophilus LMG 18311 3164110 YP_138591.1 CDS tnp1239 NC_006448.1 51414 52454 R IS1239 transposase complement(51414..52454) Streptococcus thermophilus LMG 18311 3165618 YP_138592.1 CDS argS NC_006448.1 53012 54703 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(53012..54703) Streptococcus thermophilus LMG 18311 3164079 YP_138593.1 CDS argR NC_006448.1 54828 55286 D arginine repressor ArgR 54828..55286 Streptococcus thermophilus LMG 18311 3165547 YP_138594.1 CDS stu0049 NC_006448.1 55286 55645 D hypothetical protein 55286..55645 Streptococcus thermophilus LMG 18311 3164969 YP_138595.1 CDS mutS1 NC_006448.1 55638 58196 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 55638..58196 Streptococcus thermophilus LMG 18311 3164933 YP_138596.1 CDS stu0051 NC_006448.1 58443 58685 R hypothetical protein complement(58443..58685) Streptococcus thermophilus LMG 18311 3164095 YP_138597.1 CDS stu0052 NC_006448.1 58699 59073 R hypothetical protein complement(58699..59073) Streptococcus thermophilus LMG 18311 3163960 YP_138598.1 CDS stu0053 NC_006448.1 59297 59602 D hypothetical protein 59297..59602 Streptococcus thermophilus LMG 18311 3165190 YP_138599.1 CDS mutL NC_006448.1 59654 61597 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 59654..61597 Streptococcus thermophilus LMG 18311 3163886 YP_138600.1 CDS stu0055 NC_006448.1 61724 61948 D hypothetical protein 61724..61948 Streptococcus thermophilus LMG 18311 3164033 YP_138601.1 CDS ruvA NC_006448.1 62100 62690 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 62100..62690 Streptococcus thermophilus LMG 18311 3164088 YP_138602.1 CDS tag NC_006448.1 62697 63251 D 3-methyl-adenine DNA glycosylase I 62697..63251 Streptococcus thermophilus LMG 18311 3164836 YP_138603.1 CDS cinA NC_006448.1 63347 64618 D competence damage-inducible protein A 63347..64618 Streptococcus thermophilus LMG 18311 3164587 YP_138604.1 CDS recA NC_006448.1 64654 65808 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 64654..65808 Streptococcus thermophilus LMG 18311 3165147 YP_138605.1 CDS spxA NC_006448.1 65985 66383 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 65985..66383 Streptococcus thermophilus LMG 18311 3163895 YP_138606.1 CDS polC NC_006448.1 72791 77185 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 72791..77185 Streptococcus thermophilus LMG 18311 3164718 YP_138607.1 CDS pepS NC_006448.1 77349 78590 D aminopeptidase 77349..78590 Streptococcus thermophilus LMG 18311 3164370 YP_138608.1 CDS stu0064 NC_006448.1 78610 78840 D hypothetical protein 78610..78840 Streptococcus thermophilus LMG 18311 3164917 YP_138609.1 CDS stu0065 NC_006448.1 79043 79372 D truncated; MarR family transcriptional regulator 79043..79372 Streptococcus thermophilus LMG 18311 3164745 YP_138610.1 CDS stu0066 NC_006448.1 79490 80041 D hypothetical protein 79490..80041 Streptococcus thermophilus LMG 18311 3163967 YP_138611.1 CDS stu0067 NC_006448.1 80091 80240 R truncated; hypothetical protein complement(80091..80240) Streptococcus thermophilus LMG 18311 3164320 YP_138612.1 CDS stu0068 NC_006448.1 80345 80578 R truncated; hypothetical protein complement(80345..80578) Streptococcus thermophilus LMG 18311 3164938 YP_138613.1 CDS stu0069 NC_006448.1 80592 80855 R truncated; hypothetical protein complement(80592..80855) Streptococcus thermophilus LMG 18311 3164103 YP_138614.1 CDS stu0070 NC_006448.1 80982 81254 R hypothetical protein complement(80982..81254) Streptococcus thermophilus LMG 18311 3164918 YP_138615.1 CDS stu0071 NC_006448.1 81472 81909 R truncated; bacteriocin self-immunity protein, truncated complement(81472..81909) Streptococcus thermophilus LMG 18311 3163912 YP_138616.1 CDS stu0072 NC_006448.1 81906 82424 R truncated; bacteriocin self-immunity protein, truncated complement(81906..82424) Streptococcus thermophilus LMG 18311 3165031 YP_138617.1 CDS rpsB NC_006448.1 82947 83714 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 82947..83714 Streptococcus thermophilus LMG 18311 3164167 YP_138618.2 CDS tsf NC_006448.1 83825 84865 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 83825..84865 Streptococcus thermophilus LMG 18311 3165200 YP_138619.1 CDS stu0075 NC_006448.1 84976 85446 R hypothetical protein complement(84976..85446) Streptococcus thermophilus LMG 18311 3164169 YP_138620.1 CDS ctsR NC_006448.1 85690 86145 D transcriptional regulator 85690..86145 Streptococcus thermophilus LMG 18311 3165537 YP_138621.1 CDS clpC NC_006448.1 86146 88596 D ATP-dependent Clp protease, ATP-binding subunit 86146..88596 Streptococcus thermophilus LMG 18311 3164874 YP_138622.1 CDS stu0078 NC_006448.1 88724 89545 R truncated; D-alanyl-D-alanine carboxypeptidase, truncated complement(88724..89545) Streptococcus thermophilus LMG 18311 3164615 YP_138623.1 CDS stu0079 NC_006448.1 89607 89774 R truncated; D-alanyl-D-alanine carboxypeptidase, truncated complement(89607..89774) Streptococcus thermophilus LMG 18311 3163907 YP_138624.1 CDS dacA1 NC_006448.1 90127 91395 R D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein complement(90127..91395) Streptococcus thermophilus LMG 18311 3163971 YP_138625.1 CDS pnpA NC_006448.1 91583 93808 D polynucleotide phosphorylase 91583..93808 Streptococcus thermophilus LMG 18311 3163849 YP_138626.1 CDS stu0082 NC_006448.1 93817 94587 D hypothetical protein 93817..94587 Streptococcus thermophilus LMG 18311 3164078 YP_138627.1 CDS cysE1 NC_006448.1 94651 95280 D serine acetyltransferase 94651..95280 Streptococcus thermophilus LMG 18311 3164589 YP_138628.1 CDS cysS NC_006448.1 95662 97005 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 95662..97005 Streptococcus thermophilus LMG 18311 3163839 YP_138629.1 CDS stu0085 NC_006448.1 96998 97399 D hypothetical protein 96998..97399 Streptococcus thermophilus LMG 18311 3163880 YP_138630.1 CDS stu0086 NC_006448.1 97682 97837 D hypothetical protein 97682..97837 Streptococcus thermophilus LMG 18311 3163956 YP_138631.1 CDS stu0087 NC_006448.1 97913 98101 D hypothetical protein 97913..98101 Streptococcus thermophilus LMG 18311 3164824 YP_138632.1 CDS trmH NC_006448.1 98463 99206 D tRNA/rRNA methyltransferase 98463..99206 Streptococcus thermophilus LMG 18311 3164100 YP_138633.1 CDS stu0089 NC_006448.1 99209 99724 D hypothetical protein 99209..99724 Streptococcus thermophilus LMG 18311 3165161 YP_138634.1 CDS stu0090 NC_006448.1 99733 100593 D hypothetical protein 99733..100593 Streptococcus thermophilus LMG 18311 3164096 YP_138635.1 CDS stu0091 NC_006448.1 100894 101364 D hypothetical protein 100894..101364 Streptococcus thermophilus LMG 18311 3164060 YP_138636.1 CDS panE NC_006448.1 101543 102499 D 2-dehydropantoate 2-reductase 101543..102499 Streptococcus thermophilus LMG 18311 3165152 YP_138637.1 CDS rplM NC_006448.1 102708 103154 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 102708..103154 Streptococcus thermophilus LMG 18311 3163814 YP_138638.1 CDS rpsI NC_006448.1 103182 103574 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 103182..103574 Streptococcus thermophilus LMG 18311 3164409 YP_138639.1 CDS stu0095 NC_006448.1 103734 103976 R truncated; integrase/recombinase, truncated complement(103734..103976) Streptococcus thermophilus LMG 18311 3164235 YP_138640.1 CDS stu0096 NC_006448.1 104051 104314 D truncated; transcriptional regulator, truncated 104051..104314 Streptococcus thermophilus LMG 18311 3163940 YP_138641.1 CDS stu0097 NC_006448.1 104564 104668 D hypothetical protein 104564..104668 Streptococcus thermophilus LMG 18311 3163835 YP_138642.1 CDS labB NC_006448.1 104847 107651 D lantibiotic biosynthesis protein 104847..107651 Streptococcus thermophilus LMG 18311 3164002 YP_138643.1 CDS labC NC_006448.1 107689 108912 D lantibiotic biosynthesis protein 107689..108912 Streptococcus thermophilus LMG 18311 3164001 YP_138644.1 CDS labT NC_006448.1 108936 109811 D bacteriocin exporter 108936..109811 Streptococcus thermophilus LMG 18311 3164928 YP_138645.1 CDS stu0101 NC_006448.1 110429 110941 D hypothetical protein 110429..110941 Streptococcus thermophilus LMG 18311 3164044 YP_138646.1 CDS int NC_006448.1 111278 112495 R phage integrase family integrase/recombinase complement(111278..112495) Streptococcus thermophilus LMG 18311 3163999 YP_138647.1 CDS stu0103 NC_006448.1 112976 114031 R hypothetical protein complement(112976..114031) Streptococcus thermophilus LMG 18311 3164793 YP_138648.1 CDS stu0106 NC_006448.1 114278 114535 R truncated; hypothetical protein complement(114278..114535) Streptococcus thermophilus LMG 18311 3165619 YP_138649.1 CDS stu0107 NC_006448.1 115043 115426 R truncated; truncated IS1216 transposase complement(115043..115426) Streptococcus thermophilus LMG 18311 3164584 YP_138650.1 CDS stu0108 NC_006448.1 115451 115729 R truncated; truncated IS1216 transposase complement(115451..115729) Streptococcus thermophilus LMG 18311 3163766 YP_138651.1 CDS stu0110 NC_006448.1 115915 117096 D hypothetical protein 115915..117096 Streptococcus thermophilus LMG 18311 3163753 YP_138652.1 CDS stu0112 NC_006448.1 117418 117684 D ACT domain-containing protein; hypothetical protein 117418..117684 Streptococcus thermophilus LMG 18311 3164507 YP_138653.1 CDS stu0113 NC_006448.1 117696 119039 D hypothetical protein 117696..119039 Streptococcus thermophilus LMG 18311 3164764 YP_138654.1 CDS stu0114 NC_006448.1 119156 119578 D truncated; phosphoglycerate mutase, truncated 119156..119578 Streptococcus thermophilus LMG 18311 3164113 YP_138655.1 CDS stu0115 NC_006448.1 119701 119880 D truncated; phosphoglycerate mutase, truncated 119701..119880 Streptococcus thermophilus LMG 18311 3163981 YP_138656.1 CDS dacB NC_006448.1 119867 120664 D D-alanyl-D-alanine-carboxypeptidase 119867..120664 Streptococcus thermophilus LMG 18311 3164456 YP_138657.1 CDS mur3 NC_006448.1 120661 121245 D peptidoglycan hydrolase 120661..121245 Streptococcus thermophilus LMG 18311 3164652 YP_138658.1 CDS hrcA NC_006448.1 121435 122517 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 121435..122517 Streptococcus thermophilus LMG 18311 3164703 YP_138659.1 CDS grpE NC_006448.1 122501 123082 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 122501..123082 Streptococcus thermophilus LMG 18311 3164252 YP_138660.1 CDS dnaK NC_006448.1 123211 125034 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 123211..125034 Streptococcus thermophilus LMG 18311 3164693 YP_138661.1 CDS dnaJ NC_006448.1 125461 126594 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 125461..126594 Streptococcus thermophilus LMG 18311 3165008 YP_138662.1 CDS truA NC_006448.1 126700 127446 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 126700..127446 Streptococcus thermophilus LMG 18311 3165101 YP_138663.1 CDS thiD NC_006448.1 127439 128200 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 127439..128200 Streptococcus thermophilus LMG 18311 3164024 YP_138664.1 CDS stu0124 NC_006448.1 128291 128659 D hypothetical protein 128291..128659 Streptococcus thermophilus LMG 18311 3164012 YP_138665.1 CDS amiA2 NC_006448.1 140604 142571 D oligopeptide ABC uptake transporter substrate-binding protein 140604..142571 Streptococcus thermophilus LMG 18311 3164291 YP_138666.1 CDS stu0126 NC_006448.1 142609 143520 R truncated; truncated IS1193 transposase complement(142609..143520) Streptococcus thermophilus LMG 18311 3164023 YP_138667.1 CDS stu0127 NC_006448.1 144438 144866 D truncated; aminoacylase/N-acyl-L-amino acid amidohydrolase, truncated 144438..144866 Streptococcus thermophilus LMG 18311 3164389 YP_138668.1 CDS cfa NC_006448.1 144960 146159 D cyclopropane-fatty-acyl-phospholipid synthase 144960..146159 Streptococcus thermophilus LMG 18311 3163935 YP_138669.1 CDS stu0129 NC_006448.1 146390 146884 R truncated; truncated IS1193 transposase complement(146390..146884) Streptococcus thermophilus LMG 18311 3164588 YP_138670.1 CDS comX NC_006448.1 147638 148135 D transcriptional regulator 147638..148135 Streptococcus thermophilus LMG 18311 3163739 YP_138671.1 CDS stu0131 NC_006448.1 148235 149077 R mechanosensitive ion channel MscS complement(148235..149077) Streptococcus thermophilus LMG 18311 3164420 YP_138672.1 CDS tig NC_006448.1 149218 150501 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 149218..150501 Streptococcus thermophilus LMG 18311 3165119 YP_138673.1 CDS rpoE NC_006448.1 150659 151240 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 150659..151240 Streptococcus thermophilus LMG 18311 3164435 YP_138674.1 CDS pyrG NC_006448.1 151491 153095 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 151491..153095 Streptococcus thermophilus LMG 18311 3164539 YP_138675.1 CDS stu0135 NC_006448.1 153190 153660 D hypothetical protein 153190..153660 Streptococcus thermophilus LMG 18311 3164032 YP_138676.1 CDS stu0136 NC_006448.1 153676 154122 D MutT/nudix family protein 153676..154122 Streptococcus thermophilus LMG 18311 3163989 YP_138677.1 CDS prmA NC_006448.1 154122 155075 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 154122..155075 Streptococcus thermophilus LMG 18311 3164711 YP_138678.1 CDS stu0138 NC_006448.1 155076 155819 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 155076..155819 Streptococcus thermophilus LMG 18311 3164699 YP_138679.1 CDS stu0139 NC_006448.1 156114 156494 D truncated; cyclo-nucleotide phosphodiesterase, truncated 156114..156494 Streptococcus thermophilus LMG 18311 3164942 YP_138680.1 CDS stu0140 NC_006448.1 156514 156699 D truncated; cyclo-nucleotide phosphodiesterase, truncated 156514..156699 Streptococcus thermophilus LMG 18311 3164222 YP_138681.1 CDS stu0141 NC_006448.1 156683 157444 D truncated; cyclo-nucleotide phosphodiesterase, truncated 156683..157444 Streptococcus thermophilus LMG 18311 3164035 YP_138682.1 CDS stu0142 NC_006448.1 157456 158205 D truncated; cyclo-nucleotide phosphodiesterase, truncated 157456..158205 Streptococcus thermophilus LMG 18311 3164066 YP_138683.1 CDS stu0143 NC_006448.1 158195 158584 D hypothetical protein 158195..158584 Streptococcus thermophilus LMG 18311 3164226 YP_138684.1 CDS nrdI NC_006448.1 158571 159098 R has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI complement(158571..159098) Streptococcus thermophilus LMG 18311 3164045 YP_138685.1 CDS relA NC_006448.1 159198 161417 D (p)ppGpp synthetase 159198..161417 Streptococcus thermophilus LMG 18311 3164475 YP_138686.1 CDS dtd NC_006448.1 161430 161873 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 161430..161873 Streptococcus thermophilus LMG 18311 3164029 YP_138687.1 CDS stu0147 NC_006448.1 162314 162598 D truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 162314..162598 Streptococcus thermophilus LMG 18311 3164038 YP_138688.1 CDS stu0148 NC_006448.1 162753 163043 D truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 162753..163043 Streptococcus thermophilus LMG 18311 3165015 YP_138689.1 CDS stu0149 NC_006448.1 163239 163850 D truncated; 1,6-alpha-glucanhydrolase (dextranase), truncated 163239..163850 Streptococcus thermophilus LMG 18311 3164792 YP_138690.1 CDS ilvA NC_006448.1 164150 165400 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 164150..165400 Streptococcus thermophilus LMG 18311 3165033 YP_138691.1 CDS def NC_006448.1 165561 166175 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(165561..166175) Streptococcus thermophilus LMG 18311 3163998 YP_138692.1 CDS stu0152 NC_006448.1 166277 166915 R transcriptional regulator complement(166277..166915) Streptococcus thermophilus LMG 18311 3164041 YP_138693.1 CDS stu0153 NC_006448.1 167022 168185 D hypothetical protein 167022..168185 Streptococcus thermophilus LMG 18311 3163893 YP_138694.1 CDS rpsO NC_006448.1 168334 168603 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 168334..168603 Streptococcus thermophilus LMG 18311 3164150 YP_138695.1 CDS stu0155 NC_006448.1 168833 169414 R hypothetical protein complement(168833..169414) Streptococcus thermophilus LMG 18311 3164733 YP_138696.1 CDS stu0156 NC_006448.1 169983 170153 D hypothetical protein 169983..170153 Streptococcus thermophilus LMG 18311 3164783 YP_138697.1 CDS stu0157 NC_006448.1 170240 170347 D hypothetical protein 170240..170347 Streptococcus thermophilus LMG 18311 3163819 YP_138698.1 CDS stu0158 NC_006448.1 170436 171176 R polar amino acid ABC uptake transporter ATP-binding protein complement(170436..171176) Streptococcus thermophilus LMG 18311 3164768 YP_138699.1 CDS stu0159 NC_006448.1 171176 172726 R polar amino acid ABC uptake transporter substrate binding protein/membrane-spanning protein complement(171176..172726) Streptococcus thermophilus LMG 18311 3164674 YP_138700.1 CDS uppP NC_006448.1 172917 173783 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 172917..173783 Streptococcus thermophilus LMG 18311 3165178 YP_138701.1 CDS stu0161 NC_006448.1 173929 174144 R hypothetical protein complement(173929..174144) Streptococcus thermophilus LMG 18311 3164053 YP_138702.1 CDS mecA NC_006448.1 174410 175159 D enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 174410..175159 Streptococcus thermophilus LMG 18311 3164052 YP_138703.1 CDS rgpG NC_006448.1 175163 176320 D exopolysaccharide biosynthesis protein, glycosyltransferase 175163..176320 Streptococcus thermophilus LMG 18311 3164984 YP_138704.1 CDS stu0164 NC_006448.1 176448 177251 D ABC transporter ATP binding protein 176448..177251 Streptococcus thermophilus LMG 18311 3164616 YP_138705.1 CDS stu0165 NC_006448.1 177288 178550 D hypothetical protein 177288..178550 Streptococcus thermophilus LMG 18311 3164657 YP_138706.1 CDS nifS1 NC_006448.1 178604 179836 D aminotransferase 178604..179836 Streptococcus thermophilus LMG 18311 3164275 YP_138707.1 CDS nifU NC_006448.1 179802 180257 D NifU family protein 179802..180257 Streptococcus thermophilus LMG 18311 3164744 YP_138708.1 CDS stu0168 NC_006448.1 180337 181755 D hypothetical protein 180337..181755 Streptococcus thermophilus LMG 18311 3165064 YP_138709.1 CDS stu0169 NC_006448.1 182039 182245 D truncated; oligopeptide ABC uptake transporter substrate binding protein, truncated 182039..182245 Streptococcus thermophilus LMG 18311 3163784 YP_138710.1 CDS stu0170 NC_006448.1 182220 183074 D truncated; oligopeptide ABC uptake transporter substrate binding protein, truncated 182220..183074 Streptococcus thermophilus LMG 18311 3163799 YP_138711.1 CDS stu0171 NC_006448.1 183064 183273 D truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 183064..183273 Streptococcus thermophilus LMG 18311 3165586 YP_138712.1 CDS stu0172 NC_006448.1 183403 183951 D truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 183403..183951 Streptococcus thermophilus LMG 18311 3163858 YP_138713.1 CDS stu0173 NC_006448.1 183932 184318 D truncated; oligopeptide ABC uptake transporter membrane-spanning protein, truncated 183932..184318 Streptococcus thermophilus LMG 18311 3164071 YP_138714.1 CDS stu0174 NC_006448.1 184290 184532 D truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 184290..184532 Streptococcus thermophilus LMG 18311 3164914 YP_138715.1 CDS stu0175 NC_006448.1 184562 184765 D truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 184562..184765 Streptococcus thermophilus LMG 18311 3164401 YP_138716.1 CDS stu0176 NC_006448.1 184743 185141 D truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 184743..185141 Streptococcus thermophilus LMG 18311 3164364 YP_138717.1 CDS stu0177 NC_006448.1 185036 185374 D truncated; oligopeptide ABC uptake transporter ATP binding protein, truncated 185036..185374 Streptococcus thermophilus LMG 18311 3164236 YP_138718.1 CDS optF NC_006448.1 185376 186314 D oligopeptide ABC uptake transporter membrane-spanning protein 185376..186314 Streptococcus thermophilus LMG 18311 3164902 YP_138719.1 CDS stu0179 NC_006448.1 186536 186724 D hypothetical protein 186536..186724 Streptococcus thermophilus LMG 18311 3164400 YP_138720.1 CDS hslO NC_006448.1 186850 187737 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 186850..187737 Streptococcus thermophilus LMG 18311 3164547 YP_138721.1 CDS nifR NC_006448.1 187655 188707 D transcriptional regulator 187655..188707 Streptococcus thermophilus LMG 18311 3164111 YP_138722.1 CDS stu0182 NC_006448.1 189057 189773 D MutR family transcriptional regulator 189057..189773 Streptococcus thermophilus LMG 18311 3164656 YP_138723.1 CDS stu0183 NC_006448.1 190043 192382 D protein kinase 190043..192382 Streptococcus thermophilus LMG 18311 3164586 YP_138724.1 CDS stu0184 NC_006448.1 192383 193651 D hypothetical protein 192383..193651 Streptococcus thermophilus LMG 18311 3164732 YP_138725.1 CDS adcR NC_006448.1 193745 194200 D zinc transport transcriptional repressor 193745..194200 Streptococcus thermophilus LMG 18311 3164452 YP_138726.1 CDS adcC NC_006448.1 194202 194909 D zinc (Zn2+) ABC uptake transporter ATP-binding protein 194202..194909 Streptococcus thermophilus LMG 18311 3163926 YP_138727.1 CDS adcB NC_006448.1 194875 195714 D zinc (Zn2+) ABC uptake transporter membrane-spanning protein 194875..195714 Streptococcus thermophilus LMG 18311 3164186 YP_138728.1 CDS mleP NC_006448.1 195876 196814 D AEC family permease 195876..196814 Streptococcus thermophilus LMG 18311 3164412 YP_138729.1 CDS stu0189 NC_006448.1 196929 197360 D truncated; glucose PTS enzyme component IIABC, truncated 196929..197360 Streptococcus thermophilus LMG 18311 3164639 YP_138730.1 CDS stu0190 NC_006448.1 197474 197590 D truncated; glucose PTS enzyme component IIABC, truncated 197474..197590 Streptococcus thermophilus LMG 18311 3165042 YP_138731.1 CDS stu0191 NC_006448.1 197606 198532 D truncated; glucose PTS enzyme component IIABC, truncated 197606..198532 Streptococcus thermophilus LMG 18311 3164176 YP_138732.1 CDS stu0192 NC_006448.1 198483 199151 D truncated; glucose PTS enzyme component IIABC, truncated 198483..199151 Streptococcus thermophilus LMG 18311 3165185 YP_138733.1 CDS stu0193 NC_006448.1 199192 200064 D hypothetical protein 199192..200064 Streptococcus thermophilus LMG 18311 3164220 YP_138734.1 CDS pgi NC_006448.1 200149 201522 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 200149..201522 Streptococcus thermophilus LMG 18311 3164355 YP_138735.2 CDS stu0195 NC_006448.1 201710 202426 D hypothetical protein 201710..202426 Streptococcus thermophilus LMG 18311 3164978 YP_138736.1 CDS yajC NC_006448.1 202552 202890 D preprotein translocase subunit YajC 202552..202890 Streptococcus thermophilus LMG 18311 3164912 YP_138737.1 CDS uppS NC_006448.1 203019 203768 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 203019..203768 Streptococcus thermophilus LMG 18311 3163754 YP_138738.1 CDS cdsA NC_006448.1 203781 204575 D phosphatidate cytidylyltransferase 203781..204575 Streptococcus thermophilus LMG 18311 3164913 YP_138739.1 CDS eep NC_006448.1 204592 205854 D hypothetical protein 204592..205854 Streptococcus thermophilus LMG 18311 3164352 YP_138740.1 CDS proS NC_006448.1 205925 207787 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 205925..207787 Streptococcus thermophilus LMG 18311 3164931 YP_138741.1 CDS stu0201 NC_006448.1 208365 210344 D ABC transporter substrate binding/membrane-spanning protein 208365..210344 Streptococcus thermophilus LMG 18311 3164105 YP_138742.1 CDS stu0202 NC_006448.1 210344 211147 D ABC transporter ATP binding protein 210344..211147 Streptococcus thermophilus LMG 18311 3164607 YP_138743.2 CDS groES NC_006448.1 211315 211602 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 211315..211602 Streptococcus thermophilus LMG 18311 3164998 YP_138744.1 CDS groEL NC_006448.1 211651 213270 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 211651..213270 Streptococcus thermophilus LMG 18311 3164027 YP_138745.1 CDS stu0205 NC_006448.1 213403 213822 D truncated; hypothetical protein 213403..213822 Streptococcus thermophilus LMG 18311 3164025 YP_138746.1 CDS stu0206 NC_006448.1 213829 214209 D truncated; hypothetical protein 213829..214209 Streptococcus thermophilus LMG 18311 3163811 YP_138747.1 CDS stu0207 NC_006448.1 214267 214485 D truncated; hypothetical protein 214267..214485 Streptococcus thermophilus LMG 18311 3164957 YP_138748.1 CDS stu0208 NC_006448.1 214678 214905 R hypothetical protein complement(214678..214905) Streptococcus thermophilus LMG 18311 3164155 YP_138749.1 CDS stu0209 NC_006448.1 215496 215801 R hypothetical protein complement(215496..215801) Streptococcus thermophilus LMG 18311 3164727 YP_138750.1 CDS stu0210 NC_006448.1 215801 215992 R hypothetical protein complement(215801..215992) Streptococcus thermophilus LMG 18311 3165053 YP_138751.1 CDS stu0211 NC_006448.1 216313 217185 R ribosomal large subunit pseudouridine synthase D complement(216313..217185) Streptococcus thermophilus LMG 18311 3164034 YP_138752.1 CDS pbp2A NC_006448.1 217251 219578 D penicillin-binding protein 2A 217251..219578 Streptococcus thermophilus LMG 18311 3164856 YP_138753.1 CDS rpmG NC_006448.1 219627 219779 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 219627..219779 Streptococcus thermophilus LMG 18311 3165039 YP_138754.1 CDS secE NC_006448.1 219788 219964 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 219788..219964 Streptococcus thermophilus LMG 18311 3164302 YP_138755.1 CDS nusG NC_006448.1 220161 220700 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 220161..220700 Streptococcus thermophilus LMG 18311 3164820 YP_138756.1 CDS stu0216 NC_006448.1 220822 221310 D hypothetical protein 220822..221310 Streptococcus thermophilus LMG 18311 3163836 YP_138757.1 CDS stu0217 NC_006448.1 221442 221783 R truncated; hypothetical protein complement(221442..221783) Streptococcus thermophilus LMG 18311 3164405 YP_138758.1 CDS stu0218 NC_006448.1 222036 222272 R truncated; hypothetical protein complement(222036..222272) Streptococcus thermophilus LMG 18311 3163965 YP_138759.1 CDS stu0219 NC_006448.1 222247 223011 R DeoR family transcriptional regulator complement(222247..223011) Streptococcus thermophilus LMG 18311 3164180 YP_138760.1 CDS leuS NC_006448.1 223185 225686 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 223185..225686 Streptococcus thermophilus LMG 18311 3164502 YP_138761.1 CDS stu0221 NC_006448.1 225775 225966 D hypothetical protein 225775..225966 Streptococcus thermophilus LMG 18311 3163840 YP_138762.1 CDS stu0222 NC_006448.1 225997 226134 D hypothetical protein 225997..226134 Streptococcus thermophilus LMG 18311 3165221 YP_138763.1 CDS tnp1239 NC_006448.1 226455 227495 R IS1239 transposase complement(226455..227495) Streptococcus thermophilus LMG 18311 3165617 YP_138764.1 CDS stu0224 NC_006448.1 227640 228152 D truncated; acyl-CoA thioesterase 227640..228152 Streptococcus thermophilus LMG 18311 3164909 YP_138765.1 CDS stu0225 NC_006448.1 228103 228861 D truncated; acyl-CoA thioesterase 228103..228861 Streptococcus thermophilus LMG 18311 3164196 YP_138766.2 CDS pncB NC_006448.1 229155 230609 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 229155..230609 Streptococcus thermophilus LMG 18311 3164077 YP_138767.1 CDS nadE NC_006448.1 230621 231442 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 230621..231442 Streptococcus thermophilus LMG 18311 3163948 YP_138768.1 CDS stu0228 NC_006448.1 231458 231898 D hypothetical protein 231458..231898 Streptococcus thermophilus LMG 18311 3165103 YP_138769.1 CDS pepC NC_006448.1 232000 233337 D cysteine aminopeptidase 232000..233337 Streptococcus thermophilus LMG 18311 3163969 YP_138770.1 CDS pbp1A NC_006448.1 233447 235777 R penicillin-binding protein 1A complement(233447..235777) Streptococcus thermophilus LMG 18311 3164335 YP_138771.1 CDS recU NC_006448.1 235777 236373 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(235777..236373) Streptococcus thermophilus LMG 18311 3163759 YP_138772.1 CDS stu0232 NC_006448.1 236450 236965 D hypothetical protein 236450..236965 Streptococcus thermophilus LMG 18311 3165108 YP_138773.1 CDS stu0233 NC_006448.1 237074 237406 D GpsB; guiding PBP1 shuttling; similar to DivIVA; cell division protein GpsB 237074..237406 Streptococcus thermophilus LMG 18311 3164259 YP_138774.1 CDS stu0234 NC_006448.1 237933 239105 D hypothetical protein 237933..239105 Streptococcus thermophilus LMG 18311 3164379 YP_138775.1 CDS stu0235 NC_006448.1 239108 240970 D hypothetical protein 239108..240970 Streptococcus thermophilus LMG 18311 3165106 YP_138776.1 CDS snf NC_006448.1 241081 244176 D ATP-dependent RNA helicase 241081..244176 Streptococcus thermophilus LMG 18311 3164726 YP_138777.1 CDS stu0238 NC_006448.1 244332 245048 D hypothetical protein 244332..245048 Streptococcus thermophilus LMG 18311 3165226 YP_138778.1 CDS murC NC_006448.1 245060 246403 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 245060..246403 Streptococcus thermophilus LMG 18311 3164378 YP_138779.1 CDS stu0240 NC_006448.1 246489 246956 D acetyltransferase 246489..246956 Streptococcus thermophilus LMG 18311 3164838 YP_138780.1 CDS pabC NC_006448.1 247056 249032 D aminodeoxychorismate lyase 247056..249032 Streptococcus thermophilus LMG 18311 3163885 YP_138781.1 CDS greA NC_006448.1 249116 249598 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 249116..249598 Streptococcus thermophilus LMG 18311 3163879 YP_138782.1 CDS stu0243 NC_006448.1 250003 250095 D truncated; hypothetical protein 250003..250095 Streptococcus thermophilus LMG 18311 3164816 YP_138783.1 CDS stu0244 NC_006448.1 250142 250492 D truncated; hypothetical protein 250142..250492 Streptococcus thermophilus LMG 18311 3164980 YP_138784.1 CDS stu0245 NC_006448.1 250548 251465 R involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein complement(250548..251465) Streptococcus thermophilus LMG 18311 3164414 YP_138785.1 CDS acyP NC_006448.1 251552 251830 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(251552..251830) Streptococcus thermophilus LMG 18311 3165600 YP_138786.1 CDS spoU NC_006448.1 251933 252670 D rRNA methyltransferase 251933..252670 Streptococcus thermophilus LMG 18311 3164189 YP_138787.1 CDS stu0248 NC_006448.1 252772 253266 D hydrolase 252772..253266 Streptococcus thermophilus LMG 18311 3163846 YP_138788.1 CDS stu0249 NC_006448.1 253300 253989 D hypothetical protein 253300..253989 Streptococcus thermophilus LMG 18311 3165194 YP_138789.1 CDS stu0250 NC_006448.1 254100 254396 R hypothetical protein complement(254100..254396) Streptococcus thermophilus LMG 18311 3163829 YP_138790.1 CDS stu0251 NC_006448.1 254771 255109 R hypothetical protein complement(254771..255109) Streptococcus thermophilus LMG 18311 3164509 YP_138791.1 CDS lysA NC_006448.1 255284 256549 D diaminopimelate decarboxylase 255284..256549 Streptococcus thermophilus LMG 18311 3164868 YP_138792.1 CDS stu0253 NC_006448.1 256579 257118 R TetR/AcrR family transcriptional regulator complement(256579..257118) Streptococcus thermophilus LMG 18311 3163978 YP_138793.1 CDS stu0254 NC_006448.1 257359 257604 D hypothetical protein 257359..257604 Streptococcus thermophilus LMG 18311 3164966 YP_138794.1 CDS glr NC_006448.1 257670 258485 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 257670..258485 Streptococcus thermophilus LMG 18311 3163834 YP_138795.1 CDS stu0256 NC_006448.1 258478 259452 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein 258478..259452 Streptococcus thermophilus LMG 18311 3165007 YP_138796.1 CDS stu0257 NC_006448.1 259434 259955 D hypothetical protein 259434..259955 Streptococcus thermophilus LMG 18311 3164147 YP_138797.1 CDS stu0258 NC_006448.1 259952 260434 D hypothetical protein 259952..260434 Streptococcus thermophilus LMG 18311 3164161 YP_138798.1 CDS xerD NC_006448.1 260388 261149 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 260388..261149 Streptococcus thermophilus LMG 18311 3164562 YP_138799.1 CDS scpA NC_006448.1 261149 261862 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 261149..261862 Streptococcus thermophilus LMG 18311 3163899 YP_138800.1 CDS scpB NC_006448.1 261855 262436 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 261855..262436 Streptococcus thermophilus LMG 18311 3164050 YP_138801.1 CDS rluB NC_006448.1 262487 263254 D ribosomal large subunit pseudouridine synthase B 262487..263254 Streptococcus thermophilus LMG 18311 3163869 YP_138802.1 CDS stu0263 NC_006448.1 263251 263502 D hypothetical protein 263251..263502 Streptococcus thermophilus LMG 18311 3164037 YP_138803.1 CDS trkH1 NC_006448.1 263525 264964 R K+ transporter (Trk), membrane-spanning protein complement(263525..264964) Streptococcus thermophilus LMG 18311 3165133 YP_138804.1 CDS trkA NC_006448.1 264971 266320 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(264971..266320) Streptococcus thermophilus LMG 18311 3164634 YP_138805.1 CDS tnp1239 NC_006448.1 266441 267481 R IS1239 transposase complement(266441..267481) Streptococcus thermophilus LMG 18311 3164648 YP_138806.1 CDS stu0267 NC_006448.1 267808 268362 D rRNA methyltransferase 267808..268362 Streptococcus thermophilus LMG 18311 3164349 YP_138807.1 CDS stu0268 NC_006448.1 268596 269231 D hypothetical protein 268596..269231 Streptococcus thermophilus LMG 18311 3164120 YP_138808.1 CDS stu0269 NC_006448.1 269234 269884 D hypothetical protein 269234..269884 Streptococcus thermophilus LMG 18311 3165614 YP_138809.1 CDS plcR NC_006448.1 270090 270989 D transcriptional regulator 270090..270989 Streptococcus thermophilus LMG 18311 3164013 YP_138810.1 CDS stu0271 NC_006448.1 271164 271388 D truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 271164..271388 Streptococcus thermophilus LMG 18311 3163911 YP_138811.1 CDS stu0272 NC_006448.1 271419 272084 D truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 271419..272084 Streptococcus thermophilus LMG 18311 3165612 YP_138812.1 CDS stu0273 NC_006448.1 272115 272405 D truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272115..272405 Streptococcus thermophilus LMG 18311 3164307 YP_138813.1 CDS stu0274 NC_006448.1 272427 272834 D truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272427..272834 Streptococcus thermophilus LMG 18311 3164754 YP_138814.1 CDS stu0275 NC_006448.1 272840 273259 D truncated; peptide-2 ABC transporter ATP binding/membrane-spanning protein truncated 272840..273259 Streptococcus thermophilus LMG 18311 3164580 YP_138815.1 CDS stu0276 NC_006448.1 273367 273684 D hypothetical protein 273367..273684 Streptococcus thermophilus LMG 18311 3164332 YP_138816.1 CDS stu0277 NC_006448.1 274171 274971 R truncated; urease cluster protein, truncated complement(274171..274971) Streptococcus thermophilus LMG 18311 3164171 YP_138817.1 CDS ureI NC_006448.1 275472 275987 D urea channel 275472..275987 Streptococcus thermophilus LMG 18311 3164904 YP_138818.1 CDS ureA NC_006448.1 276012 276314 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 276012..276314 Streptococcus thermophilus LMG 18311 3164063 YP_138819.1 CDS ureB NC_006448.1 276326 276637 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 276326..276637 Streptococcus thermophilus LMG 18311 3163757 YP_138820.1 CDS ureC NC_006448.1 276653 278371 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 276653..278371 Streptococcus thermophilus LMG 18311 3164271 YP_138821.1 CDS ureE NC_006448.1 278512 278964 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 278512..278964 Streptococcus thermophilus LMG 18311 3164345 YP_138822.1 CDS ureF NC_006448.1 278954 279667 D urease accessory protein 278954..279667 Streptococcus thermophilus LMG 18311 3164107 YP_138823.1 CDS ureG NC_006448.1 279697 280311 D urease accessory protein 279697..280311 Streptococcus thermophilus LMG 18311 3164994 YP_138824.1 CDS ureD NC_006448.1 280313 281152 D urease accessory protein 280313..281152 Streptococcus thermophilus LMG 18311 3164278 YP_138825.1 CDS cbiM NC_006448.1 281156 282133 D catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 281156..282133 Streptococcus thermophilus LMG 18311 3164854 YP_138826.1 CDS stu0289 NC_006448.1 282130 282909 D ABC transporter membrane-spanning protein 282130..282909 Streptococcus thermophilus LMG 18311 3165202 YP_138827.1 CDS stu0290 NC_006448.1 282911 283624 D ABC transporter ATP-binding protein 282911..283624 Streptococcus thermophilus LMG 18311 3163993 YP_138828.1 CDS stu0291 NC_006448.1 283789 284637 D ABC transporter substrate binding protein 283789..284637 Streptococcus thermophilus LMG 18311 3164398 YP_138829.1 CDS pps NC_006448.1 284827 287718 D non-ribosomal peptide synthetase 284827..287718 Streptococcus thermophilus LMG 18311 3165204 YP_138830.1 CDS stu0293 NC_006448.1 287715 289361 D hypothetical protein 287715..289361 Streptococcus thermophilus LMG 18311 3164423 YP_138831.1 CDS stu0294 NC_006448.1 289387 290595 D drug:H+ antiporter-3 (DHA3) family protein 289387..290595 Streptococcus thermophilus LMG 18311 3164557 YP_138832.1 CDS stu0295 NC_006448.1 290976 291170 R truncated; hypothetical protein complement(290976..291170) Streptococcus thermophilus LMG 18311 3164844 YP_138833.1 CDS stu0296 NC_006448.1 291302 292150 D polar amino acid ABC uptake transporter substrate binding protein 291302..292150 Streptococcus thermophilus LMG 18311 3164921 YP_138834.1 CDS stu0297 NC_006448.1 292310 293212 D ABC transporter substrate binding protein 292310..293212 Streptococcus thermophilus LMG 18311 3165559 YP_138835.1 CDS stu0298 NC_006448.1 293273 293755 D truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 293273..293755 Streptococcus thermophilus LMG 18311 3163854 YP_138836.1 CDS stu0299 NC_006448.1 293813 294178 D truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 293813..294178 Streptococcus thermophilus LMG 18311 3163805 YP_138837.1 CDS stu0300 NC_006448.1 294263 294646 D truncated; succinyl-diaminopimelic descuccinlyasadipeptidase, truncated 294263..294646 Streptococcus thermophilus LMG 18311 3163933 YP_138838.1 CDS stu0301 NC_006448.1 294639 295706 D polar amino acid ABC uptake transporter ATP binding protein 294639..295706 Streptococcus thermophilus LMG 18311 3164679 YP_138839.1 CDS stu0302 NC_006448.1 295706 296398 D ABC transporter membrane-spanning protein 295706..296398 Streptococcus thermophilus LMG 18311 3164076 YP_138840.1 CDS dctA NC_006448.1 296521 297729 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 296521..297729 Streptococcus thermophilus LMG 18311 3165098 YP_138841.1 CDS stu0304 NC_006448.1 297882 298094 D truncated; hypothetical protein 297882..298094 Streptococcus thermophilus LMG 18311 3164114 YP_138842.1 CDS stu0305 NC_006448.1 298127 298732 D truncated; hypothetical protein 298127..298732 Streptococcus thermophilus LMG 18311 3164617 YP_138843.1 CDS stu0306 NC_006448.1 298742 298945 D truncated; hypothetical protein 298742..298945 Streptococcus thermophilus LMG 18311 3163920 YP_138844.1 CDS stu0307 NC_006448.1 299045 299293 D truncated; hypothetical protein 299045..299293 Streptococcus thermophilus LMG 18311 3164018 YP_138845.1 CDS stu0308 NC_006448.1 299329 299574 D truncated; ABC transporter ATP binding protein, truncated 299329..299574 Streptococcus thermophilus LMG 18311 3164623 YP_138846.1 CDS stu0309 NC_006448.1 299630 301036 D truncated; ABC transporter ATP binding protein, truncated 299630..301036 Streptococcus thermophilus LMG 18311 3163771 YP_138847.1 CDS stu0310 NC_006448.1 301029 301163 D truncated; ABC transporter membrane-spanning protein, truncated 301029..301163 Streptococcus thermophilus LMG 18311 3164907 YP_138848.1 CDS stu0311 NC_006448.1 301142 301681 D truncated; ABC transporter membrane-spanning protein, truncated 301142..301681 Streptococcus thermophilus LMG 18311 3165167 YP_138849.1 CDS tkt NC_006448.1 302032 304008 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 302032..304008 Streptococcus thermophilus LMG 18311 3164919 YP_138850.1 CDS trkA2 NC_006448.1 304257 304928 R K+ transporter (Trk), NAD+ binding protein complement(304257..304928) Streptococcus thermophilus LMG 18311 3165615 YP_138851.1 CDS trkH2 NC_006448.1 304968 306353 R K+ transporter (Trk), membrane-spanning protein complement(304968..306353) Streptococcus thermophilus LMG 18311 3164492 YP_138852.1 CDS gidB NC_006448.1 306402 307115 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(306402..307115) Streptococcus thermophilus LMG 18311 3164578 YP_138853.1 CDS stu0316 NC_006448.1 307406 307948 D hypothetical protein 307406..307948 Streptococcus thermophilus LMG 18311 3165139 YP_138854.1 CDS rr01 NC_006448.1 308104 308793 D response regulator 308104..308793 Streptococcus thermophilus LMG 18311 3164368 YP_138855.1 CDS hk01 NC_006448.1 308790 310307 D sensor histidine kinase 308790..310307 Streptococcus thermophilus LMG 18311 3164274 YP_138856.2 CDS nrdR NC_006448.1 310429 310908 D transcriptional regulator NrdR 310429..310908 Streptococcus thermophilus LMG 18311 3165572 YP_138857.1 CDS dnaB NC_006448.1 310905 312080 D chromosome replication initiation / membrane attachment protein DnaB 310905..312080 Streptococcus thermophilus LMG 18311 3164876 YP_138858.1 CDS dnaI NC_006448.1 312084 312986 D Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 312084..312986 Streptococcus thermophilus LMG 18311 3163768 YP_138859.1 CDS engA NC_006448.1 313092 314402 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 313092..314402 Streptococcus thermophilus LMG 18311 3164244 YP_138860.1 CDS stu0324 NC_006448.1 315589 317178 R peptide-2 ABC transporter ATP binding/membrane-spanning protein complement(315589..317178) Streptococcus thermophilus LMG 18311 3165097 YP_138861.1 CDS stu0325 NC_006448.1 317162 317950 R hypothetical protein complement(317162..317950) Streptococcus thermophilus LMG 18311 3163767 YP_138862.1 CDS tnp1191 NC_006448.1 318122 319330 D IS1191 transposase 318122..319330 Streptococcus thermophilus LMG 18311 3164273 YP_138863.1 CDS stu0328 NC_006448.1 319377 319610 R hypothetical protein complement(319377..319610) Streptococcus thermophilus LMG 18311 3164212 YP_138864.2 CDS serS NC_006448.1 319973 321250 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(319973..321250) Streptococcus thermophilus LMG 18311 3164960 YP_138865.1 CDS stu0330 NC_006448.1 321459 321833 R hypothetical protein complement(321459..321833) Streptococcus thermophilus LMG 18311 3164402 YP_138866.1 CDS manN NC_006448.1 321912 322823 R mannose PTS system component IID complement(321912..322823) Streptococcus thermophilus LMG 18311 3164377 YP_138867.1 CDS manM NC_006448.1 322838 323665 R mannose PTS system component IIC complement(322838..323665) Streptococcus thermophilus LMG 18311 3164399 YP_138868.1 CDS manL NC_006448.1 323733 324725 R mannose PTS system component IIAB complement(323733..324725) Streptococcus thermophilus LMG 18311 3164692 YP_138869.1 CDS stu0334 NC_006448.1 325101 325832 D hypothetical protein 325101..325832 Streptococcus thermophilus LMG 18311 3164163 YP_138870.1 CDS stu0335 NC_006448.1 325877 326677 R hypothetical protein complement(325877..326677) Streptococcus thermophilus LMG 18311 3164208 YP_138871.1 CDS stu0336 NC_006448.1 326897 328318 D hypothetical protein 326897..328318 Streptococcus thermophilus LMG 18311 3164084 YP_138872.1 CDS stu0337 NC_006448.1 328590 329033 D hypothetical protein 328590..329033 Streptococcus thermophilus LMG 18311 3163982 YP_138873.1 CDS stu0338 NC_006448.1 329026 329547 D acetyltransferase 329026..329547 Streptococcus thermophilus LMG 18311 3164432 YP_138874.1 CDS stu0339 NC_006448.1 329556 330782 D transcriptional regulator 329556..330782 Streptococcus thermophilus LMG 18311 3165176 YP_138875.1 CDS stu0340 NC_006448.1 330905 331396 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 330905..331396 Streptococcus thermophilus LMG 18311 3165151 YP_138876.1 CDS nusA NC_006448.1 331462 332649 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 331462..332649 Streptococcus thermophilus LMG 18311 3164418 YP_138877.1 CDS stu0342 NC_006448.1 332667 332966 D hypothetical protein 332667..332966 Streptococcus thermophilus LMG 18311 3164701 YP_138878.1 CDS stu0343 NC_006448.1 332959 333261 D hypothetical protein 332959..333261 Streptococcus thermophilus LMG 18311 3164309 YP_138879.1 CDS infB NC_006448.1 333280 336111 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 333280..336111 Streptococcus thermophilus LMG 18311 3164860 YP_138880.1 CDS rbfA NC_006448.1 336205 336558 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 336205..336558 Streptococcus thermophilus LMG 18311 3163800 YP_138881.1 CDS stu0346 NC_006448.1 336623 336916 D hypothetical protein 336623..336916 Streptococcus thermophilus LMG 18311 3164270 YP_138882.1 CDS stu0347 NC_006448.1 336900 337079 D hypothetical protein 336900..337079 Streptococcus thermophilus LMG 18311 3164953 YP_138883.1 CDS murO NC_006448.1 337454 338713 D peptidoglycan branched peptide synthesis protein 337454..338713 Streptococcus thermophilus LMG 18311 3164593 YP_138884.1 CDS murE NC_006448.1 338782 340227 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase complement(338782..340227) Streptococcus thermophilus LMG 18311 3164064 YP_138885.1 CDS stu0350 NC_006448.1 340322 341953 D polysaccharide transporter 340322..341953 Streptococcus thermophilus LMG 18311 3164763 YP_138886.1 CDS stu0351 NC_006448.1 341977 342486 D truncated; Ca2+, Mn2+-P-type ATPase, truncated 341977..342486 Streptococcus thermophilus LMG 18311 3164297 YP_138887.1 CDS metB1 NC_006448.1 342893 343987 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 342893..343987 Streptococcus thermophilus LMG 18311 3164591 YP_138888.1 CDS stu0353 NC_006448.1 343956 345161 D aminotransferase 343956..345161 Streptococcus thermophilus LMG 18311 3164786 YP_138889.1 CDS stu0354 NC_006448.1 345445 345720 D hypothetical protein 345445..345720 Streptococcus thermophilus LMG 18311 3163988 YP_138890.1 CDS upp NC_006448.1 345850 346479 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 345850..346479 Streptococcus thermophilus LMG 18311 3165010 YP_138891.1 CDS clpP NC_006448.1 346617 347207 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 346617..347207 Streptococcus thermophilus LMG 18311 3164125 YP_138892.1 CDS stu0357 NC_006448.1 347294 347743 D hypothetical protein 347294..347743 Streptococcus thermophilus LMG 18311 3165003 YP_138893.1 CDS stu0358 NC_006448.1 347736 348017 D hypothetical protein 347736..348017 Streptococcus thermophilus LMG 18311 3165004 YP_138894.1 CDS livJ NC_006448.1 348174 349349 D branched-chain amino acid ABC uptake transporter substrate-binding protein 348174..349349 Streptococcus thermophilus LMG 18311 3164649 YP_138895.1 CDS livH NC_006448.1 349393 350277 D branched-chain amino acid ABC uptake transporter membrane-spanning protein 349393..350277 Streptococcus thermophilus LMG 18311 3164312 YP_138896.1 CDS livM NC_006448.1 350281 351231 D branched-chain amino acid ABC uptake transporter membrane-spanning protein 350281..351231 Streptococcus thermophilus LMG 18311 3163986 YP_138897.1 CDS livG NC_006448.1 351234 351998 D branched-chain amino acid ABC uptake transporter ATP binding protein 351234..351998 Streptococcus thermophilus LMG 18311 3164314 YP_138898.1 CDS livF NC_006448.1 351998 352708 D branched chain amino acid ABC uptake transporter ATP binding protein 351998..352708 Streptococcus thermophilus LMG 18311 3164553 YP_138899.1 CDS stu0364 NC_006448.1 352862 353281 D truncated; acetoin utilization protein, truncated 352862..353281 Streptococcus thermophilus LMG 18311 3164734 YP_138900.1 CDS stu0365 NC_006448.1 353226 353504 D truncated; acetoin utilization protein, truncated 353226..353504 Streptococcus thermophilus LMG 18311 3164158 YP_138901.1 CDS cysM1 NC_006448.1 353671 354603 R cysteine synthase complement(353671..354603) Streptococcus thermophilus LMG 18311 3164849 YP_138902.1 CDS stu0367 NC_006448.1 354699 355325 R hypothetical protein complement(354699..355325) Streptococcus thermophilus LMG 18311 3164669 YP_138903.1 CDS comFA NC_006448.1 355380 356699 D late competence protein required for DNA uptake 355380..356699 Streptococcus thermophilus LMG 18311 3165094 YP_138904.1 CDS comFC NC_006448.1 356674 357342 D late competence protein 356674..357342 Streptococcus thermophilus LMG 18311 3164704 YP_138905.1 CDS stu0370 NC_006448.1 357421 357969 D ribosomal protein S30AE family protein 357421..357969 Streptococcus thermophilus LMG 18311 3164975 YP_138906.1 CDS ppaC NC_006448.1 363881 364813 D catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 363881..364813 Streptococcus thermophilus LMG 18311 3164072 YP_138907.1 CDS stu0373 NC_006448.1 364867 365526 D hypothetical protein 364867..365526 Streptococcus thermophilus LMG 18311 3164852 YP_138908.1 CDS stu0374 NC_006448.1 365556 366089 R hypothetical protein complement(365556..366089) Streptococcus thermophilus LMG 18311 3163918 YP_138909.1 CDS recX NC_006448.1 366160 366936 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(366160..366936) Streptococcus thermophilus LMG 18311 3164463 YP_138910.1 CDS stu0376 NC_006448.1 366971 368335 D TrmA family tRNA methyltransferase 366971..368335 Streptococcus thermophilus LMG 18311 3164242 YP_138911.1 CDS asnA NC_006448.1 368434 369426 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 368434..369426 Streptococcus thermophilus LMG 18311 3164565 YP_138912.1 CDS lysC NC_006448.1 369578 370936 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(369578..370936) Streptococcus thermophilus LMG 18311 3164322 YP_138913.1 CDS stu0379 NC_006448.1 371068 371706 D beta-phosphoglucomutase 371068..371706 Streptococcus thermophilus LMG 18311 3164308 YP_138914.1 CDS phaB NC_006448.1 371919 372710 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 371919..372710 Streptococcus thermophilus LMG 18311 3164046 YP_138915.1 CDS stu0381 NC_006448.1 372814 373248 D MarR family transcriptional regulator 372814..373248 Streptococcus thermophilus LMG 18311 3164787 YP_138916.1 CDS fabH NC_006448.1 373248 374210 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 373248..374210 Streptococcus thermophilus LMG 18311 3164049 YP_138917.1 CDS acpP NC_006448.1 374274 374498 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 374274..374498 Streptococcus thermophilus LMG 18311 3165585 YP_138918.1 CDS fabK NC_006448.1 374604 375569 D trans-2-enoyl-ACP reductase II 374604..375569 Streptococcus thermophilus LMG 18311 3164202 YP_138919.1 CDS fabD NC_006448.1 375586 376512 D ACP S-malonyltransferase 375586..376512 Streptococcus thermophilus LMG 18311 3164516 YP_138920.1 CDS fabG NC_006448.1 376525 377259 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 376525..377259 Streptococcus thermophilus LMG 18311 3165100 YP_138921.1 CDS fabF NC_006448.1 377321 378553 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 377321..378553 Streptococcus thermophilus LMG 18311 3164900 YP_138922.1 CDS accB NC_006448.1 378557 379045 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 378557..379045 Streptococcus thermophilus LMG 18311 3163779 YP_138923.1 CDS fabZ NC_006448.1 379042 379467 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 379042..379467 Streptococcus thermophilus LMG 18311 3164081 YP_138924.2 CDS accC NC_006448.1 379587 380957 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 379587..380957 Streptococcus thermophilus LMG 18311 3165142 YP_138925.1 CDS accD NC_006448.1 380963 381829 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 380963..381829 Streptococcus thermophilus LMG 18311 3164019 YP_138926.1 CDS accA NC_006448.1 381826 382596 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 381826..382596 Streptococcus thermophilus LMG 18311 3163987 YP_138927.1 CDS luxS NC_006448.1 382627 383109 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(382627..383109) Streptococcus thermophilus LMG 18311 3164501 YP_138928.1 CDS stu0395 NC_006448.1 383256 383492 D truncated; type I restriction modification system specificity subunit, truncated 383256..383492 Streptococcus thermophilus LMG 18311 3164577 YP_138929.1 CDS tnp1216 NC_006448.1 383643 384323 D IS1216 transposase 383643..384323 Streptococcus thermophilus LMG 18311 3164117 YP_138930.1 CDS stu0397 NC_006448.1 384737 386344 D hypothetical protein 384737..386344 Streptococcus thermophilus LMG 18311 3164599 YP_138931.1 CDS stu0398 NC_006448.1 386673 387212 R truncated; hypothetical protein complement(386673..387212) Streptococcus thermophilus LMG 18311 3164845 YP_138932.1 CDS fruR NC_006448.1 387770 388516 D transcriptional repressor 387770..388516 Streptococcus thermophilus LMG 18311 3164151 YP_138933.1 CDS fruB NC_006448.1 388513 389424 D fructose-1-phosphate kinase 388513..389424 Streptococcus thermophilus LMG 18311 3165621 YP_138934.1 CDS stu0401 NC_006448.1 389454 390167 D truncated; fructose PTS system component IIABC, truncated 389454..390167 Streptococcus thermophilus LMG 18311 3164895 YP_138935.1 CDS stu0405 NC_006448.1 390164 390673 D truncated; fructose PTS system component IIABC, truncated 390164..390673 Streptococcus thermophilus LMG 18311 3164457 YP_138936.1 CDS stu0406 NC_006448.1 390728 391087 D truncated; fructose PTS system component IIABC, truncated 390728..391087 Streptococcus thermophilus LMG 18311 3164116 YP_138937.1 CDS stu0407 NC_006448.1 391080 391397 D truncated; fructose PTS system component IIABC, truncated 391080..391397 Streptococcus thermophilus LMG 18311 3163761 YP_138938.1 CDS gor NC_006448.1 391547 392899 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 391547..392899 Streptococcus thermophilus LMG 18311 3164765 YP_138939.1 CDS folC1 NC_006448.1 393001 394257 R folylpolyglutamate synthase / dihydrofolate synthase complement(393001..394257) Streptococcus thermophilus LMG 18311 3164357 YP_138940.1 CDS stu0410 NC_006448.1 394303 394845 R hypothetical protein complement(394303..394845) Streptococcus thermophilus LMG 18311 3164609 YP_138941.1 CDS nifS2 NC_006448.1 394954 396099 D aminotransferase 394954..396099 Streptococcus thermophilus LMG 18311 3164950 YP_138942.1 CDS thiI NC_006448.1 396154 397377 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 396154..397377 Streptococcus thermophilus LMG 18311 3164341 YP_138943.1 CDS stu0413 NC_006448.1 397483 398994 D glycosyltransferase teichoic acid biosynthesis protein 397483..398994 Streptococcus thermophilus LMG 18311 3164504 YP_138944.1 CDS stu0414 NC_006448.1 398987 400306 D hypothetical protein 398987..400306 Streptococcus thermophilus LMG 18311 3163905 YP_138945.1 CDS stu0416 NC_006448.1 400619 400846 D truncated; hypothetical protein 400619..400846 Streptococcus thermophilus LMG 18311 3163742 YP_138946.2 CDS rplU NC_006448.1 401075 401389 D 50S ribosomal protein L21 401075..401389 Streptococcus thermophilus LMG 18311 3163866 YP_138947.1 CDS rpmA NC_006448.1 401426 401716 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 401426..401716 Streptococcus thermophilus LMG 18311 3164622 YP_138948.1 CDS stu0419 NC_006448.1 401775 402302 D truncated; acetyltransferase 401775..402302 Streptococcus thermophilus LMG 18311 3164621 YP_138949.1 CDS stu0420 NC_006448.1 402202 402471 D truncated; acetyltransferase 402202..402471 Streptococcus thermophilus LMG 18311 3165143 YP_138950.1 CDS stu0421 NC_006448.1 402672 403046 D hypothetical protein 402672..403046 Streptococcus thermophilus LMG 18311 3164381 YP_138951.1 CDS stu0422 NC_006448.1 403048 403260 D truncated; hypothetical protein 403048..403260 Streptococcus thermophilus LMG 18311 3165206 YP_138952.1 CDS stu0423 NC_006448.1 403253 403891 D truncated; hypothetical protein 403253..403891 Streptococcus thermophilus LMG 18311 3165129 YP_138953.1 CDS dapB NC_006448.1 403952 404719 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 403952..404719 Streptococcus thermophilus LMG 18311 3164650 YP_138954.1 CDS papL NC_006448.1 404716 405924 D catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 404716..405924 Streptococcus thermophilus LMG 18311 3163884 YP_138955.1 CDS stu0426 NC_006448.1 406002 407882 D ABC transporter ATP-binding protein 406002..407882 Streptococcus thermophilus LMG 18311 3164748 YP_138956.1 CDS stu0427 NC_006448.1 407964 408467 R hypothetical protein complement(407964..408467) Streptococcus thermophilus LMG 18311 3165199 YP_138957.1 CDS stu0428 NC_006448.1 408544 409230 R MutT/nudix family protein complement(408544..409230) Streptococcus thermophilus LMG 18311 3164747 YP_138958.1 CDS nadR NC_006448.1 409360 410466 R transcriptional regulator complement(409360..410466) Streptococcus thermophilus LMG 18311 3164613 YP_138959.1 CDS gdhA NC_006448.1 410792 412162 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 410792..412162 Streptococcus thermophilus LMG 18311 3164350 YP_138960.1 CDS defA NC_006448.1 412421 412831 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 412421..412831 Streptococcus thermophilus LMG 18311 3165196 YP_138961.1 CDS stu0432 NC_006448.1 413023 413466 D MarR family transcriptional regulator 413023..413466 Streptococcus thermophilus LMG 18311 3164682 YP_138962.1 CDS lmrA1 NC_006448.1 413470 415284 D multidrug ABC exporter ATP binding/membrane-spanning protein 413470..415284 Streptococcus thermophilus LMG 18311 3164659 YP_138963.1 CDS lmrA2 NC_006448.1 415274 417052 D multidrug ABC exporter ATP binding/membrane-spanning protein 415274..417052 Streptococcus thermophilus LMG 18311 3164651 YP_138964.1 CDS stu0435 NC_006448.1 417208 417456 D hypothetical protein 417208..417456 Streptococcus thermophilus LMG 18311 3164664 YP_138965.1 CDS stu0437 NC_006448.1 417952 418668 D truncated; sensor histidine kinase, uncoupled, truncated 417952..418668 Streptococcus thermophilus LMG 18311 3164796 YP_138966.1 CDS pyrH NC_006448.1 419000 419737 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 419000..419737 Streptococcus thermophilus LMG 18311 3164247 YP_138967.1 CDS frr NC_006448.1 419752 420309 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 419752..420309 Streptococcus thermophilus LMG 18311 3164839 YP_138968.1 CDS stu0440 NC_006448.1 420358 421257 D hypothetical protein 420358..421257 Streptococcus thermophilus LMG 18311 3164794 YP_138969.1 CDS stu0441 NC_006448.1 421266 421481 D hypothetical protein 421266..421481 Streptococcus thermophilus LMG 18311 3164296 YP_138970.1 CDS pcsB NC_006448.1 421722 423170 D glucan-binding protein B 421722..423170 Streptococcus thermophilus LMG 18311 3163984 YP_138971.1 CDS stu0446 NC_006448.1 423413 423928 D truncated; surface immunogenic protein, truncated 423413..423928 Streptococcus thermophilus LMG 18311 3164696 YP_138972.1 CDS phoH NC_006448.1 424008 425069 D phosphate starvation-induced protein 424008..425069 Streptococcus thermophilus LMG 18311 3164885 YP_138973.1 CDS stu0448 NC_006448.1 426277 426690 D hypothetical protein 426277..426690 Streptococcus thermophilus LMG 18311 3163942 YP_138974.1 CDS stu0449 NC_006448.1 427161 427367 D hypothetical protein 427161..427367 Streptococcus thermophilus LMG 18311 3164700 YP_138975.1 CDS stu0450 NC_006448.1 427364 427771 D hypothetical protein 427364..427771 Streptococcus thermophilus LMG 18311 3164685 YP_138976.1 CDS metG NC_006448.1 427965 429968 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 427965..429968 Streptococcus thermophilus LMG 18311 3165177 YP_138977.1 CDS stu0452 NC_006448.1 430246 431148 R LysR family transcriptional regulator complement(430246..431148) Streptococcus thermophilus LMG 18311 3165029 YP_138978.1 CDS coiA NC_006448.1 432356 433399 D competence protein, transcription factor 432356..433399 Streptococcus thermophilus LMG 18311 3164447 YP_138979.1 CDS pepB NC_006448.1 433410 435215 D oligopeptidase 433410..435215 Streptococcus thermophilus LMG 18311 3164705 YP_138980.1 CDS stu0455 NC_006448.1 435398 436105 D methyltransferase 435398..436105 Streptococcus thermophilus LMG 18311 3164738 YP_138981.1 CDS prtM NC_006448.1 436167 437282 D protease maturation protein 436167..437282 Streptococcus thermophilus LMG 18311 3164369 YP_138982.1 CDS alaS NC_006448.1 437624 440242 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 437624..440242 Streptococcus thermophilus LMG 18311 3164962 YP_138983.1 CDS stu0458 NC_006448.1 440404 440625 D truncated; cell wall protein precursor, choline binding protein, truncated 440404..440625 Streptococcus thermophilus LMG 18311 3164087 YP_138984.1 CDS stu0459 NC_006448.1 440656 441279 D truncated; cell wall protein precursor, choline binding protein, truncated 440656..441279 Streptococcus thermophilus LMG 18311 3164720 YP_138985.1 CDS stu0460 NC_006448.1 441406 441669 D truncated; cell wall protein precursor, choline binding protein, truncated 441406..441669 Streptococcus thermophilus LMG 18311 3164342 YP_138986.1 CDS cbpD3 NC_006448.1 441949 442938 D cell wall protein, choline binding protein 441949..442938 Streptococcus thermophilus LMG 18311 3164119 YP_138987.1 CDS stu0462 NC_006448.1 443071 443859 D hypothetical protein 443071..443859 Streptococcus thermophilus LMG 18311 3164193 YP_138988.1 CDS aspC3 NC_006448.1 443869 445050 D produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; transaminase 443869..445050 Streptococcus thermophilus LMG 18311 3164353 YP_138989.1 CDS argC NC_006448.1 445179 446201 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 445179..446201 Streptococcus thermophilus LMG 18311 3165169 YP_138990.1 CDS argJ NC_006448.1 446230 447423 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 446230..447423 Streptococcus thermophilus LMG 18311 3164371 YP_138991.1 CDS argB NC_006448.1 447450 448187 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 447450..448187 Streptococcus thermophilus LMG 18311 3164069 YP_138992.1 CDS argD NC_006448.1 448191 449321 D acetylornithine aminotransferase 448191..449321 Streptococcus thermophilus LMG 18311 3164630 YP_138993.1 CDS stu0468 NC_006448.1 449362 450138 R hypothetical protein complement(449362..450138) Streptococcus thermophilus LMG 18311 3164713 YP_138994.1 CDS hom NC_006448.1 450413 451699 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 450413..451699 Streptococcus thermophilus LMG 18311 3164495 YP_138995.1 CDS thrB NC_006448.1 451783 452643 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 451783..452643 Streptococcus thermophilus LMG 18311 3165224 YP_138996.1 CDS stu0471 NC_006448.1 452591 453520 D chloramphenicol-sensitivity protein (RarD) family protein 452591..453520 Streptococcus thermophilus LMG 18311 3164996 YP_138997.1 CDS stu0472 NC_006448.1 453702 454250 D hypothetical protein 453702..454250 Streptococcus thermophilus LMG 18311 3164859 YP_138998.1 CDS stu0473 NC_006448.1 454385 454588 D hypothetical protein 454385..454588 Streptococcus thermophilus LMG 18311 3165150 YP_138999.1 CDS stu0474 NC_006448.1 455058 455366 D truncated; hypothetical protein 455058..455366 Streptococcus thermophilus LMG 18311 3164286 YP_139000.1 CDS stu0475 NC_006448.1 455350 455661 D truncated; hypothetical protein 455350..455661 Streptococcus thermophilus LMG 18311 3164185 YP_139001.1 CDS stu0476 NC_006448.1 455702 456007 D acetyltransferase 455702..456007 Streptococcus thermophilus LMG 18311 3164126 YP_139002.2 CDS valS NC_006448.1 456238 458889 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 456238..458889 Streptococcus thermophilus LMG 18311 3164306 YP_139003.1 CDS atpE NC_006448.1 459066 459263 D produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 459066..459263 Streptococcus thermophilus LMG 18311 3164846 YP_139004.1 CDS atpB NC_006448.1 459298 460005 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 459298..460005 Streptococcus thermophilus LMG 18311 3164386 YP_139005.1 CDS atpF NC_006448.1 460026 460523 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 460026..460523 Streptococcus thermophilus LMG 18311 3163864 YP_139006.1 CDS atpH NC_006448.1 460523 461059 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 460523..461059 Streptococcus thermophilus LMG 18311 3164940 YP_139007.1 CDS atpA NC_006448.1 461075 462580 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 461075..462580 Streptococcus thermophilus LMG 18311 3164952 YP_139008.1 CDS atpG NC_006448.1 462599 463477 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 462599..463477 Streptococcus thermophilus LMG 18311 3165544 YP_139009.1 CDS atpD NC_006448.1 463554 464960 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 463554..464960 Streptococcus thermophilus LMG 18311 3165545 YP_139010.1 CDS atpC NC_006448.1 464973 465419 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 464973..465419 Streptococcus thermophilus LMG 18311 3164245 YP_139011.1 CDS ftsW NC_006448.1 465656 466951 D cell division protein 465656..466951 Streptococcus thermophilus LMG 18311 3164082 YP_139012.1 CDS tuf NC_006448.1 467189 468385 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 467189..468385 Streptococcus thermophilus LMG 18311 3163862 YP_139013.1 CDS tpiA NC_006448.1 468634 469392 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 468634..469392 Streptococcus thermophilus LMG 18311 3164943 YP_139014.1 CDS tmk NC_006448.1 469630 470259 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 469630..470259 Streptococcus thermophilus LMG 18311 3164496 YP_139015.1 CDS dnaH NC_006448.1 470268 471143 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 470268..471143 Streptococcus thermophilus LMG 18311 3165189 YP_139016.1 CDS sip NC_006448.1 471140 471946 D signal-petidase-like protein 471140..471946 Streptococcus thermophilus LMG 18311 3164017 YP_139017.1 CDS stu0492 NC_006448.1 471933 472253 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 471933..472253 Streptococcus thermophilus LMG 18311 3164751 YP_139018.1 CDS stu0493 NC_006448.1 472256 473122 D tetrapyrrole methylase family protein 472256..473122 Streptococcus thermophilus LMG 18311 3164372 YP_139019.1 CDS amtB NC_006448.1 473212 474495 D ammonium transporter 473212..474495 Streptococcus thermophilus LMG 18311 3164636 YP_139020.1 CDS gnlB NC_006448.1 474440 474847 D nitrogen regulatory protein P-II 474440..474847 Streptococcus thermophilus LMG 18311 3164293 YP_139021.1 CDS mur1 NC_006448.1 474945 475601 D peptidoglycan hydrolase 474945..475601 Streptococcus thermophilus LMG 18311 3164769 YP_139022.1 CDS stu0497 NC_006448.1 475588 476445 D hypothetical protein 475588..476445 Streptococcus thermophilus LMG 18311 3164753 YP_139023.1 CDS stu0499 NC_006448.1 476949 477593 D truncated; Na/Pi cotransporter II-like protein, truncated 476949..477593 Streptococcus thermophilus LMG 18311 3163961 YP_139024.1 CDS stu0500 NC_006448.1 477601 477747 D truncated; Na/Pi cotransporter II-like protein, truncated 477601..477747 Streptococcus thermophilus LMG 18311 3164815 YP_139025.1 CDS nagA NC_006448.1 477814 478980 D N-acetylglucosamine-6-phosphate deacetylase 477814..478980 Streptococcus thermophilus LMG 18311 3165201 YP_139026.1 CDS stu0502 NC_006448.1 479085 479408 D truncated; hypothetical protein 479085..479408 Streptococcus thermophilus LMG 18311 3163747 YP_139027.1 CDS stu0503 NC_006448.1 479281 479583 D truncated; hypothetical protein 479281..479583 Streptococcus thermophilus LMG 18311 3164109 YP_139028.1 CDS stu0504 NC_006448.1 479567 479935 D truncated; hypothetical protein 479567..479935 Streptococcus thermophilus LMG 18311 3164897 YP_139029.1 CDS glyQ NC_006448.1 480610 481527 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 480610..481527 Streptococcus thermophilus LMG 18311 3164890 YP_139030.2 CDS glyS NC_006448.1 481811 483847 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 481811..483847 Streptococcus thermophilus LMG 18311 3164776 YP_139031.1 CDS stu0508 NC_006448.1 483860 484117 D hypothetical protein 483860..484117 Streptococcus thermophilus LMG 18311 3164803 YP_139032.1 CDS cycA NC_006448.1 484279 485679 D D-Serine/D-alanine/glycine:H+ symporter 484279..485679 Streptococcus thermophilus LMG 18311 3164304 YP_139033.1 CDS stu0510 NC_006448.1 485749 486384 R hypothetical protein complement(485749..486384) Streptococcus thermophilus LMG 18311 3165130 YP_139034.1 CDS stu0511 NC_006448.1 486688 486864 D truncated; beta-glucoside PTS system component IIABC, truncated 486688..486864 Streptococcus thermophilus LMG 18311 3165138 YP_139035.1 CDS stu0512 NC_006448.1 486877 487311 D truncated; beta-glucoside PTS system component IIABC, truncated 486877..487311 Streptococcus thermophilus LMG 18311 3164782 YP_139036.1 CDS stu0513 NC_006448.1 487356 488072 D truncated; beta-glucoside PTS system component IIABC, truncated 487356..488072 Streptococcus thermophilus LMG 18311 3164429 YP_139037.1 CDS stu0514 NC_006448.1 488050 488508 D truncated; beta-glucoside PTS system component IIABC, truncated 488050..488508 Streptococcus thermophilus LMG 18311 3163881 YP_139038.1 CDS ppiA NC_006448.1 488630 489388 R peptidyl-prolyl cis-trans isomerase complement(488630..489388) Streptococcus thermophilus LMG 18311 3164183 YP_139039.1 CDS stu0516 NC_006448.1 489750 490040 D hypothetical protein 489750..490040 Streptococcus thermophilus LMG 18311 3163843 YP_139040.1 CDS stu0517 NC_006448.1 490076 490483 D hypothetical protein 490076..490483 Streptococcus thermophilus LMG 18311 3164961 YP_139041.1 CDS stu0518 NC_006448.1 490480 490956 D hypothetical protein 490480..490956 Streptococcus thermophilus LMG 18311 3164540 YP_139042.1 CDS stu0519 NC_006448.1 491102 491326 D hypothetical protein 491102..491326 Streptococcus thermophilus LMG 18311 3164777 YP_139043.1 CDS stu0520 NC_006448.1 491433 492347 D LysR family transcriptional regulator 491433..492347 Streptococcus thermophilus LMG 18311 3164464 YP_139044.1 CDS lspA NC_006448.1 492356 492817 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 492356..492817 Streptococcus thermophilus LMG 18311 3164814 YP_139045.1 CDS rluD NC_006448.1 492801 493691 D ribosomal large subunit pseudouridine synthase D 492801..493691 Streptococcus thermophilus LMG 18311 3165584 YP_139046.1 CDS pyrR NC_006448.1 493836 494441 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 493836..494441 Streptococcus thermophilus LMG 18311 3165006 YP_139047.1 CDS pyrP NC_006448.1 494755 496065 D uracil permease 494755..496065 Streptococcus thermophilus LMG 18311 3164822 YP_139048.1 CDS pyrB NC_006448.1 496090 497016 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 496090..497016 Streptococcus thermophilus LMG 18311 3164446 YP_139049.1 CDS carA NC_006448.1 497169 498257 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 497169..498257 Streptococcus thermophilus LMG 18311 3165132 YP_139050.1 CDS carB NC_006448.1 498602 501781 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 498602..501781 Streptococcus thermophilus LMG 18311 3164841 YP_139051.1 CDS stu0528 NC_006448.1 502158 502916 D hypothetical protein 502158..502916 Streptococcus thermophilus LMG 18311 3165198 YP_139052.1 CDS stu0529 NC_006448.1 503387 503497 D hypothetical protein 503387..503497 Streptococcus thermophilus LMG 18311 3164831 YP_139053.1 CDS stu0530 NC_006448.1 503635 504027 D hypothetical protein 503635..504027 Streptococcus thermophilus LMG 18311 3164030 YP_139054.1 CDS stu0531 NC_006448.1 504020 504124 D truncated; ABC transporter membrane-spanning protein, truncated 504020..504124 Streptococcus thermophilus LMG 18311 3164691 YP_139055.1 CDS stu0532 NC_006448.1 504134 504445 D truncated; ABC transporter membrane-spanning protein, truncated 504134..504445 Streptococcus thermophilus LMG 18311 3163970 YP_139056.1 CDS stu0533 NC_006448.1 504454 504849 D truncated; ABC transporter membrane-spanning protein, truncated 504454..504849 Streptococcus thermophilus LMG 18311 3164843 YP_139057.1 CDS stu0535 NC_006448.1 504846 505061 D truncated; ABC transporter membrane-spanning protein, truncated 504846..505061 Streptococcus thermophilus LMG 18311 3164671 YP_139058.2 CDS rplJ NC_006448.1 505352 505855 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 505352..505855 Streptococcus thermophilus LMG 18311 3164145 YP_139059.2 CDS rplL NC_006448.1 505930 506298 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 505930..506298 Streptococcus thermophilus LMG 18311 3164249 YP_139060.1 CDS stu0538 NC_006448.1 507552 509288 D lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 507552..509288 Streptococcus thermophilus LMG 18311 3163972 YP_139061.1 CDS stu0539 NC_006448.1 509301 511088 D lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 509301..511088 Streptococcus thermophilus LMG 18311 3164128 YP_139062.1 CDS queA NC_006448.1 511186 512229 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(511186..512229) Streptococcus thermophilus LMG 18311 3164779 YP_139063.1 CDS nagB NC_006448.1 512304 513080 D glucosamine-6-phosphate isomerase 512304..513080 Streptococcus thermophilus LMG 18311 3163801 YP_139064.1 CDS hk02 NC_006448.1 513246 514541 R sensor histidine kinase complement(513246..514541) Streptococcus thermophilus LMG 18311 3164842 YP_139065.1 CDS rr02 NC_006448.1 514541 515266 R response regulator complement(514541..515266) Streptococcus thermophilus LMG 18311 3164241 YP_139066.1 CDS stu0545 NC_006448.1 515474 516721 D molybdopterin biosynthesis protein (HesA/MoeB/ThiF family protein) 515474..516721 Streptococcus thermophilus LMG 18311 3164864 YP_139067.1 CDS stu0546 NC_006448.1 516682 517629 D ABC transporter ATP binding protein 516682..517629 Streptococcus thermophilus LMG 18311 3164325 YP_139068.1 CDS stu0547 NC_006448.1 517631 518353 D ABC transporter membrane-spanning protein 517631..518353 Streptococcus thermophilus LMG 18311 3165594 YP_139069.1 CDS stu0548 NC_006448.1 518542 519525 D hypothetical protein 518542..519525 Streptococcus thermophilus LMG 18311 3164383 YP_139070.1 CDS stu0549 NC_006448.1 519683 519901 D transcriptional repressor 519683..519901 Streptococcus thermophilus LMG 18311 3164473 YP_139071.1 CDS stu0550 NC_006448.1 519915 520412 D hypothetical protein 519915..520412 Streptococcus thermophilus LMG 18311 3163887 YP_139072.1 CDS stu0551 NC_006448.1 520491 521261 D phosphorylase Pnp/Udp family protein 520491..521261 Streptococcus thermophilus LMG 18311 3164406 YP_139073.1 CDS stu0552 NC_006448.1 521353 522036 D hypothetical protein 521353..522036 Streptococcus thermophilus LMG 18311 3165012 YP_139074.1 CDS rsuA1 NC_006448.1 522116 522835 D ribosomal small subunit pseudouridine synthase A 522116..522835 Streptococcus thermophilus LMG 18311 3164187 YP_139075.1 CDS hipO1 NC_006448.1 523071 524216 D aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase 523071..524216 Streptococcus thermophilus LMG 18311 3164243 YP_139076.1 CDS stu0555 NC_006448.1 524649 524786 D truncated; alanine dehydrogenase 524649..524786 Streptococcus thermophilus LMG 18311 3164444 YP_139077.1 CDS stu0556 NC_006448.1 524761 525048 D truncated; alanine dehydrogenase 524761..525048 Streptococcus thermophilus LMG 18311 3165624 YP_139078.1 CDS stu0557 NC_006448.1 525757 527073 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 525757..527073 Streptococcus thermophilus LMG 18311 3164896 YP_139079.1 CDS stu0558 NC_006448.1 527292 527855 R hypothetical protein complement(527292..527855) Streptococcus thermophilus LMG 18311 3164903 YP_139080.1 CDS mvaK1 NC_006448.1 528118 528996 D mevalonate kinase 528118..528996 Streptococcus thermophilus LMG 18311 3164392 YP_139081.1 CDS mvaD NC_006448.1 528978 529922 D mevalonate pyrophosphate decarboxylase 528978..529922 Streptococcus thermophilus LMG 18311 3164086 YP_139082.1 CDS mvaK2 NC_006448.1 529915 530910 D phosphomevalonate kinase 529915..530910 Streptococcus thermophilus LMG 18311 3165073 YP_139083.1 CDS idi NC_006448.1 530960 531967 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 530960..531967 Streptococcus thermophilus LMG 18311 3164672 YP_139084.1 CDS glmU NC_006448.1 532516 533898 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 532516..533898 Streptococcus thermophilus LMG 18311 3164227 YP_139085.1 CDS stu0564 NC_006448.1 533974 534522 D hypothetical protein 533974..534522 Streptococcus thermophilus LMG 18311 3165144 YP_139086.1 CDS stu0565 NC_006448.1 534526 534786 D hypothetical protein 534526..534786 Streptococcus thermophilus LMG 18311 3164629 YP_139087.1 CDS pfs NC_006448.1 534854 535546 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 534854..535546 Streptococcus thermophilus LMG 18311 3165025 YP_139088.1 CDS stu0567 NC_006448.1 536465 536935 D truncated; hypothetical protein 536465..536935 Streptococcus thermophilus LMG 18311 3163776 YP_139089.1 CDS stu0568 NC_006448.1 537066 537356 D hypothetical protein 537066..537356 Streptococcus thermophilus LMG 18311 3164146 YP_139090.1 CDS stu0569 NC_006448.1 537481 538485 D glycosyl transferase family protein 537481..538485 Streptococcus thermophilus LMG 18311 3165107 YP_139091.1 CDS stu0570 NC_006448.1 538486 539808 D glycosyl transferase family protein 538486..539808 Streptococcus thermophilus LMG 18311 3164419 YP_139092.1 CDS stu0571 NC_006448.1 540080 540367 D hypothetical protein 540080..540367 Streptococcus thermophilus LMG 18311 3165580 YP_139093.1 CDS thrS NC_006448.1 540521 542467 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 540521..542467 Streptococcus thermophilus LMG 18311 3164191 YP_139094.1 CDS stu0573 NC_006448.1 542517 543458 D hydrolase 542517..543458 Streptococcus thermophilus LMG 18311 3164255 YP_139095.1 CDS stu0574 NC_006448.1 543478 544344 D hypothetical protein 543478..544344 Streptococcus thermophilus LMG 18311 3164533 YP_139096.1 CDS hlyIII NC_006448.1 544851 545528 R hypothetical protein complement(544851..545528) Streptococcus thermophilus LMG 18311 3163955 YP_139097.1 CDS mvaA NC_006448.1 546146 547417 R 3-hydroxy-3-methylglutaryl-CoA reductase complement(546146..547417) Streptococcus thermophilus LMG 18311 3164877 YP_139098.1 CDS mvaS NC_006448.1 547410 548609 R hydroxymethylglutaryl-CoA synthase complement(547410..548609) Streptococcus thermophilus LMG 18311 3164875 YP_139099.1 CDS thyA NC_006448.1 548907 549767 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 548907..549767 Streptococcus thermophilus LMG 18311 3163764 YP_139100.1 CDS folA NC_006448.1 549875 550378 D dihydrofolate reductase 549875..550378 Streptococcus thermophilus LMG 18311 3164847 YP_139101.1 CDS stu0580 NC_006448.1 550383 550553 D hypothetical protein 550383..550553 Streptococcus thermophilus LMG 18311 3164945 YP_139102.1 CDS clpX NC_006448.1 550571 551797 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 550571..551797 Streptococcus thermophilus LMG 18311 3164469 YP_139103.1 CDS engB NC_006448.1 551807 552406 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 551807..552406 Streptococcus thermophilus LMG 18311 3164986 YP_139104.1 CDS rocE NC_006448.1 552461 553912 D L-arginine permease 552461..553912 Streptococcus thermophilus LMG 18311 3164977 YP_139105.1 CDS mmuM NC_006448.1 553906 554874 D converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 553906..554874 Streptococcus thermophilus LMG 18311 3164988 YP_139106.1 CDS stu0585 NC_006448.1 554987 555241 D hypothetical protein 554987..555241 Streptococcus thermophilus LMG 18311 3164404 YP_139107.1 CDS stu0586 NC_006448.1 555313 555672 D hypothetical protein 555313..555672 Streptococcus thermophilus LMG 18311 3164374 YP_139108.1 CDS stu0587 NC_006448.1 555786 556427 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(555786..556427) Streptococcus thermophilus LMG 18311 3163818 YP_139109.1 CDS parE NC_006448.1 556565 558514 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 556565..558514 Streptococcus thermophilus LMG 18311 3164809 YP_139110.1 CDS parC NC_006448.1 559088 561607 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 559088..561607 Streptococcus thermophilus LMG 18311 3164968 YP_139111.1 CDS bcaT NC_006448.1 561771 562793 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 561771..562793 Streptococcus thermophilus LMG 18311 3164999 YP_139112.1 CDS stu0591 NC_006448.1 562912 563142 D hypothetical protein 562912..563142 Streptococcus thermophilus LMG 18311 3165197 YP_139113.2 CDS rpsA NC_006448.1 563544 564746 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 563544..564746 Streptococcus thermophilus LMG 18311 3165205 YP_139114.1 CDS stu0593 NC_006448.1 565574 565810 D hypothetical protein 565574..565810 Streptococcus thermophilus LMG 18311 3164992 YP_139115.1 CDS stu0594 NC_006448.1 565968 566195 D hypothetical protein 565968..566195 Streptococcus thermophilus LMG 18311 3164051 YP_139116.1 CDS stu0595 NC_006448.1 566407 566832 D hypothetical protein 566407..566832 Streptococcus thermophilus LMG 18311 3165157 YP_139117.1 CDS murN NC_006448.1 566928 568163 D peptidoglycan branched peptide synthesis protein 566928..568163 Streptococcus thermophilus LMG 18311 3164560 YP_139118.1 CDS stu0597 NC_006448.1 568438 568596 D truncated; oxidoreductase, truncated 568438..568596 Streptococcus thermophilus LMG 18311 3163997 YP_139119.1 CDS stu0598 NC_006448.1 568612 568797 D truncated; oxidoreductase, truncated 568612..568797 Streptococcus thermophilus LMG 18311 3164356 YP_139120.1 CDS stu0599 NC_006448.1 568909 569223 D truncated; oxidoreductase, truncated 568909..569223 Streptococcus thermophilus LMG 18311 3164085 YP_139121.1 CDS stu0600 NC_006448.1 569264 569566 R hypothetical protein complement(569264..569566) Streptococcus thermophilus LMG 18311 3164979 YP_139122.1 CDS stu0601 NC_006448.1 569576 570034 R MutT/nudix family protein complement(569576..570034) Streptococcus thermophilus LMG 18311 3164964 YP_139123.1 CDS clpE NC_006448.1 570177 572435 R ATP-dependent Clp protease complement(570177..572435) Streptococcus thermophilus LMG 18311 3164624 YP_139124.1 CDS argF NC_006448.1 572613 573656 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 572613..573656 Streptococcus thermophilus LMG 18311 3164817 YP_139125.1 CDS stu0604 NC_006448.1 573725 573955 D hypothetical protein 573725..573955 Streptococcus thermophilus LMG 18311 3163875 YP_139126.1 CDS stu0605 NC_006448.1 574221 574904 D polar amino acid ABC uptake transporter membrane-spanning protein 574221..574904 Streptococcus thermophilus LMG 18311 3164879 YP_139127.1 CDS stu0606 NC_006448.1 574904 575638 D polar amino acid ABC uptake transporter ATP-binding protein 574904..575638 Streptococcus thermophilus LMG 18311 3164985 YP_139128.1 CDS feoA NC_006448.1 575812 576288 D ferrous iron uptake transporter protein A 575812..576288 Streptococcus thermophilus LMG 18311 3164397 YP_139129.1 CDS feoB NC_006448.1 576285 578423 D ferrous iron transport protein B 576285..578423 Streptococcus thermophilus LMG 18311 3164927 YP_139130.1 CDS stu0609 NC_006448.1 578810 579034 D hypothetical protein 578810..579034 Streptococcus thermophilus LMG 18311 3163936 YP_139131.1 CDS stu0610 NC_006448.1 579282 579473 D hypothetical protein 579282..579473 Streptococcus thermophilus LMG 18311 3163806 YP_139132.1 CDS folD NC_006448.1 579634 580500 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 579634..580500 Streptococcus thermophilus LMG 18311 3165051 YP_139133.1 CDS stu0612 NC_006448.1 580504 581340 D hypothetical protein 580504..581340 Streptococcus thermophilus LMG 18311 3164225 YP_139134.1 CDS pbp2B NC_006448.1 581462 583576 D penicillin-binding protein 2B 581462..583576 Streptococcus thermophilus LMG 18311 3164597 YP_139135.1 CDS recR NC_006448.1 583686 584282 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 583686..584282 Streptococcus thermophilus LMG 18311 3163888 YP_139136.1 CDS stu0615 NC_006448.1 584425 584796 D truncated; BglG family transcriptional antiterminator, truncated 584425..584796 Streptococcus thermophilus LMG 18311 3164365 YP_139137.1 CDS stu0616 NC_006448.1 584904 585221 D truncated; BglG family transcriptional antiterminator, truncated 584904..585221 Streptococcus thermophilus LMG 18311 3164767 YP_139138.1 CDS stu0617 NC_006448.1 585441 585938 D metalloprotease 585441..585938 Streptococcus thermophilus LMG 18311 3165116 YP_139139.1 CDS dgk NC_006448.1 585919 586323 D diacylglycerol kinase 585919..586323 Streptococcus thermophilus LMG 18311 3164995 YP_139140.1 CDS era NC_006448.1 586342 587241 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 586342..587241 Streptococcus thermophilus LMG 18311 3163897 YP_139141.1 CDS mutM NC_006448.1 587288 588109 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 587288..588109 Streptococcus thermophilus LMG 18311 3164043 YP_139142.1 CDS coaE NC_006448.1 588085 588699 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 588085..588699 Streptococcus thermophilus LMG 18311 3164632 YP_139143.1 CDS pmrA NC_006448.1 588750 589973 D drug:H+ antiporter-1 (DHA1) family protein 588750..589973 Streptococcus thermophilus LMG 18311 3164518 YP_139144.1 CDS rpmG NC_006448.1 589963 590109 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 589963..590109 Streptococcus thermophilus LMG 18311 3163826 YP_139145.1 CDS secG NC_006448.1 590154 590390 D preprotein translocase subunit SecG 590154..590390 Streptococcus thermophilus LMG 18311 3165111 YP_139146.1 CDS rnr NC_006448.1 590449 592902 D exoribonuclease R 590449..592902 Streptococcus thermophilus LMG 18311 3164542 YP_139147.1 CDS smpB NC_006448.1 592924 593388 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 592924..593388 Streptococcus thermophilus LMG 18311 3165625 YP_139148.1 CDS pplB NC_006448.1 593542 594948 D peptidyl-prolyl cis-trans isomerase 593542..594948 Streptococcus thermophilus LMG 18311 3164633 YP_139149.1 CDS stu0628 NC_006448.1 594950 595315 D hypothetical protein 594950..595315 Streptococcus thermophilus LMG 18311 3164853 YP_139150.1 CDS pepQ NC_006448.1 595418 596503 R dipeptidase complement(595418..596503) Streptococcus thermophilus LMG 18311 3165011 YP_139151.1 CDS ccpA NC_006448.1 596785 597819 D catabolite control protein 596785..597819 Streptococcus thermophilus LMG 18311 3163861 YP_139152.1 CDS stu0631 NC_006448.1 597878 598075 D truncated; hypothetical protein 597878..598075 Streptococcus thermophilus LMG 18311 3163812 YP_139153.1 CDS stu0632 NC_006448.1 598181 598945 D truncated; hypothetical protein 598181..598945 Streptococcus thermophilus LMG 18311 3164620 YP_139154.1 CDS grk NC_006448.1 598960 600075 D glycerate kinase 598960..600075 Streptococcus thermophilus LMG 18311 3164443 YP_139155.1 CDS stu0634 NC_006448.1 600114 600569 R hypothetical protein complement(600114..600569) Streptococcus thermophilus LMG 18311 3165171 YP_139156.1 CDS eno NC_006448.1 600778 602082 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 600778..602082 Streptococcus thermophilus LMG 18311 3164939 YP_139157.1 CDS stu0636 NC_006448.1 602580 604766 R hypothetical protein complement(602580..604766) Streptococcus thermophilus LMG 18311 3163973 YP_139158.1 CDS stu0637 NC_006448.1 604928 606091 D hypothetical protein 604928..606091 Streptococcus thermophilus LMG 18311 3164840 YP_139159.1 CDS aroD NC_006448.1 606088 606765 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 606088..606765 Streptococcus thermophilus LMG 18311 3165613 YP_139160.2 CDS aroE NC_006448.1 606755 607612 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 606755..607612 Streptococcus thermophilus LMG 18311 3164130 YP_139161.1 CDS aroB NC_006448.1 607625 608692 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 607625..608692 Streptococcus thermophilus LMG 18311 3163908 YP_139162.1 CDS aroF NC_006448.1 608693 609859 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 608693..609859 Streptococcus thermophilus LMG 18311 3165016 YP_139163.1 CDS tyrA NC_006448.1 609889 610995 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 609889..610995 Streptococcus thermophilus LMG 18311 3164277 YP_139164.1 CDS stu0643 NC_006448.1 611005 611343 D hypothetical protein 611005..611343 Streptococcus thermophilus LMG 18311 3163985 YP_139165.1 CDS hdhL NC_006448.1 611399 612349 D L-2-hydroxyisocaproate dehydrogenase 611399..612349 Streptococcus thermophilus LMG 18311 3165017 YP_139166.1 CDS aroA NC_006448.1 612430 613713 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 612430..613713 Streptococcus thermophilus LMG 18311 3165018 YP_139167.1 CDS aroK NC_006448.1 613706 614197 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 613706..614197 Streptococcus thermophilus LMG 18311 3165019 YP_139168.1 CDS pheA NC_006448.1 614188 615012 D catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 614188..615012 Streptococcus thermophilus LMG 18311 3165014 YP_139169.1 CDS stu0649 NC_006448.1 615024 616454 D truncated; negative transcriptional regualtor-PBP synthesis, truncated 615024..616454 Streptococcus thermophilus LMG 18311 3165020 YP_139170.1 CDS eetB NC_006448.1 616470 617411 R exfoliative exotoxin B complement(616470..617411) Streptococcus thermophilus LMG 18311 3164532 YP_139171.1 CDS stu0651 NC_006448.1 617427 618491 R hypothetical protein complement(617427..618491) Streptococcus thermophilus LMG 18311 3164545 YP_139172.1 CDS mip NC_006448.1 618531 619079 R macrophage infectivity potentiator--like protein complement(618531..619079) Streptococcus thermophilus LMG 18311 3164000 YP_139173.1 CDS stu0653 NC_006448.1 619295 620656 D TrmA family tRNA methyltransferase 619295..620656 Streptococcus thermophilus LMG 18311 3164074 YP_139174.1 CDS stu0654 NC_006448.1 620851 621696 D hypothetical protein 620851..621696 Streptococcus thermophilus LMG 18311 3165045 YP_139175.1 CDS stu0655 NC_006448.1 622082 622258 D truncated; site-specific DNA-methyltransferase (adenine-specific) LlaI, truncated 622082..622258 Streptococcus thermophilus LMG 18311 3165216 YP_139176.1 CDS stu0656 NC_006448.1 623139 623750 D hypothetical protein 623139..623750 Streptococcus thermophilus LMG 18311 3164036 YP_139177.1 CDS stu0657 NC_006448.1 624007 627375 D hypothetical protein 624007..627375 Streptococcus thermophilus LMG 18311 3165000 YP_139178.1 CDS stu0658 NC_006448.1 627553 628464 D hypothetical protein 627553..628464 Streptococcus thermophilus LMG 18311 3165126 YP_139179.1 CDS stu0659 NC_006448.1 628466 628789 D hypothetical protein 628466..628789 Streptococcus thermophilus LMG 18311 3164910 YP_139180.1 CDS stu0660 NC_006448.1 628786 629838 D hypothetical protein 628786..629838 Streptococcus thermophilus LMG 18311 3164899 YP_139181.1 CDS stu0661 NC_006448.1 632155 632970 R hypothetical protein complement(632155..632970) Streptococcus thermophilus LMG 18311 3164067 YP_139182.1 CDS stu0662 NC_006448.1 632970 633872 R hypothetical protein complement(632970..633872) Streptococcus thermophilus LMG 18311 3164388 YP_139183.1 CDS tex NC_006448.1 634236 636368 D transcriptional regulator 634236..636368 Streptococcus thermophilus LMG 18311 3164138 YP_139184.1 CDS stu0664 NC_006448.1 636355 636795 D hypothetical protein 636355..636795 Streptococcus thermophilus LMG 18311 3165165 YP_139185.1 CDS stu0665 NC_006448.1 636862 637125 D hypothetical protein 636862..637125 Streptococcus thermophilus LMG 18311 3164382 YP_139186.1 CDS ptsK NC_006448.1 637254 638183 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 637254..638183 Streptococcus thermophilus LMG 18311 3164981 YP_139187.1 CDS lgt NC_006448.1 638183 638974 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 638183..638974 Streptococcus thermophilus LMG 18311 3164211 YP_139188.1 CDS stu0668 NC_006448.1 639004 639495 D hypothetical protein 639004..639495 Streptococcus thermophilus LMG 18311 3165570 YP_139189.1 CDS stu0669 NC_006448.1 639508 639942 D hypothetical protein 639508..639942 Streptococcus thermophilus LMG 18311 3163977 YP_139190.1 CDS stu0670 NC_006448.1 639969 640265 R hypothetical protein complement(639969..640265) Streptococcus thermophilus LMG 18311 3163915 YP_139191.1 CDS stu0671 NC_006448.1 640498 641427 D protease 640498..641427 Streptococcus thermophilus LMG 18311 3164527 YP_139192.1 CDS stu0672 NC_006448.1 641506 642810 D U32 family peptidase 641506..642810 Streptococcus thermophilus LMG 18311 3164818 YP_139193.1 CDS bioY1 NC_006448.1 643180 643719 R biotin synthase complement(643180..643719) Streptococcus thermophilus LMG 18311 3164573 YP_139194.1 CDS stu0675 NC_006448.1 643814 644104 R hypothetical protein complement(643814..644104) Streptococcus thermophilus LMG 18311 3164929 YP_139195.1 CDS stu0676 NC_006448.1 644224 644436 D hypothetical protein 644224..644436 Streptococcus thermophilus LMG 18311 3165180 YP_139196.1 CDS mntH NC_006448.1 644473 645816 R metal ion (Mn2+-iron) transporter (NRAMP) family protein complement(644473..645816) Streptococcus thermophilus LMG 18311 3164385 YP_139197.1 CDS stu0678 NC_006448.1 646005 646313 D hypothetical protein 646005..646313 Streptococcus thermophilus LMG 18311 3165181 YP_139198.1 CDS stu0679 NC_006448.1 646332 646805 D MutT/nudix family protein 646332..646805 Streptococcus thermophilus LMG 18311 3164135 YP_139199.1 CDS stu0680 NC_006448.1 646828 648900 R hypothetical protein complement(646828..648900) Streptococcus thermophilus LMG 18311 3164425 YP_139200.1 CDS stu0681 NC_006448.1 648991 649713 R hypothetical protein complement(648991..649713) Streptococcus thermophilus LMG 18311 3164861 YP_139201.1 CDS lysS NC_006448.1 650351 651886 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(650351..651886) Streptococcus thermophilus LMG 18311 3163964 YP_139202.1 CDS stu0693 NC_006448.1 652144 652491 D hypothetical protein 652144..652491 Streptococcus thermophilus LMG 18311 3164431 YP_139203.1 CDS stu0694 NC_006448.1 652691 653245 D hypothetical protein 652691..653245 Streptococcus thermophilus LMG 18311 3165013 YP_139204.1 CDS stu0695 NC_006448.1 653235 653738 D hypothetical protein 653235..653738 Streptococcus thermophilus LMG 18311 3165048 YP_139205.1 CDS stu0696 NC_006448.1 654063 654965 D hypothetical protein 654063..654965 Streptococcus thermophilus LMG 18311 3164676 YP_139206.1 CDS gpmC NC_006448.1 655389 656027 R phosphoglycerate mutase complement(655389..656027) Streptococcus thermophilus LMG 18311 3165192 YP_139207.1 CDS stu0698 NC_006448.1 656030 656503 R transcriptional regulator complement(656030..656503) Streptococcus thermophilus LMG 18311 3165095 YP_139208.1 CDS stu0699 NC_006448.1 656618 657565 R endolysin complement(656618..657565) Streptococcus thermophilus LMG 18311 3165457 YP_139209.1 CDS stu0700 NC_006448.1 657757 658146 R hypothetical protein complement(657757..658146) Streptococcus thermophilus LMG 18311 3165522 YP_139210.1 CDS stu0701 NC_006448.1 658402 659028 R hypothetical protein complement(658402..659028) Streptococcus thermophilus LMG 18311 3164321 YP_139211.1 CDS stu0702 NC_006448.1 659275 659556 D hypothetical protein 659275..659556 Streptococcus thermophilus LMG 18311 3164801 YP_139212.1 CDS stu0704 NC_006448.1 660316 661095 D short chain dehydrogenase/reductase family oxidoreductase 660316..661095 Streptococcus thermophilus LMG 18311 3164982 YP_139213.1 CDS hsdR1 NC_006448.1 661355 664345 D type I restriction-modification system restriction subunit 661355..664345 Streptococcus thermophilus LMG 18311 3164478 YP_139214.1 CDS stu0706 NC_006448.1 664335 665969 D hypothetical protein 664335..665969 Streptococcus thermophilus LMG 18311 3165620 YP_139215.1 CDS stu0707 NC_006448.1 665970 666869 D hypothetical protein 665970..666869 Streptococcus thermophilus LMG 18311 3163756 YP_139216.1 CDS hsdS1 NC_006448.1 666884 668104 D type I restriction-modification system specificty subunit 666884..668104 Streptococcus thermophilus LMG 18311 3163763 YP_139217.1 CDS stu0709 NC_006448.1 668119 669987 D hypothetical protein 668119..669987 Streptococcus thermophilus LMG 18311 3165153 YP_139218.1 CDS stu0710 NC_006448.1 670022 670774 D hypothetical protein 670022..670774 Streptococcus thermophilus LMG 18311 3164240 YP_139219.1 CDS hsdM1 NC_006448.1 670817 672421 D type I restriction-modification system methyltransferase subunit 670817..672421 Streptococcus thermophilus LMG 18311 3163782 YP_139220.1 CDS stu0712 NC_006448.1 672628 672828 D hypothetical protein 672628..672828 Streptococcus thermophilus LMG 18311 3163815 YP_139221.1 CDS stu0713 NC_006448.1 673016 674020 D deoxyribonuclease 673016..674020 Streptococcus thermophilus LMG 18311 3164869 YP_139222.1 CDS lemA NC_006448.1 674171 674731 D cytoplasmic membrane protein 674171..674731 Streptococcus thermophilus LMG 18311 3164317 YP_139223.1 CDS htpX NC_006448.1 674733 675632 D metalloprotease; heat shock protein HtpX 674733..675632 Streptococcus thermophilus LMG 18311 3163962 YP_139224.1 CDS stu0716 NC_006448.1 675750 676223 D hypothetical protein 675750..676223 Streptococcus thermophilus LMG 18311 3165104 YP_139225.1 CDS stu0717 NC_006448.1 676220 676615 D hypothetical protein 676220..676615 Streptococcus thermophilus LMG 18311 3165021 YP_139226.1 CDS ppc NC_006448.1 676789 679611 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 676789..679611 Streptococcus thermophilus LMG 18311 3164710 YP_139227.1 CDS holA NC_006448.1 679679 680713 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 679679..680713 Streptococcus thermophilus LMG 18311 3163945 YP_139228.1 CDS sodA NC_006448.1 680751 681413 D superoxide dismutase (Mn) 680751..681413 Streptococcus thermophilus LMG 18311 3164641 YP_139229.1 CDS stu0721 NC_006448.1 681510 682889 D hypothetical protein 681510..682889 Streptococcus thermophilus LMG 18311 3164054 YP_139230.1 CDS pilD NC_006448.1 682929 683576 R prepilin peptidase type IV complement(682929..683576) Streptococcus thermophilus LMG 18311 3164973 YP_139231.1 CDS dpr NC_006448.1 683685 684206 D peroxide resistance protein,non-heme iron-containing ferritin 683685..684206 Streptococcus thermophilus LMG 18311 3164408 YP_139232.1 CDS fur NC_006448.1 684295 684732 D ferric transport regulator protein 684295..684732 Streptococcus thermophilus LMG 18311 3164102 YP_139233.1 CDS stu0725 NC_006448.1 684946 685128 D truncated; truncated IS1239 transposase 684946..685128 Streptococcus thermophilus LMG 18311 3164261 YP_139234.1 CDS stu0726 NC_006448.1 685138 685986 D truncated; truncated IS1239 transposase 685138..685986 Streptococcus thermophilus LMG 18311 3164511 YP_139235.1 CDS stu0727 NC_006448.1 686087 686293 D hypothetical protein 686087..686293 Streptococcus thermophilus LMG 18311 3164514 YP_139236.1 CDS glcK NC_006448.1 686286 687254 D glucose kinase 686286..687254 Streptococcus thermophilus LMG 18311 3165524 YP_139237.1 CDS typA NC_006448.1 687392 689239 D GTP-binding protein TypA 687392..689239 Streptococcus thermophilus LMG 18311 3164523 YP_139238.1 CDS stu0730 NC_006448.1 689263 689535 D hypothetical protein 689263..689535 Streptococcus thermophilus LMG 18311 3164415 YP_139239.1 CDS murD NC_006448.1 689658 691010 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 689658..691010 Streptococcus thermophilus LMG 18311 3164596 YP_139240.1 CDS murG NC_006448.1 691014 692084 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 691014..692084 Streptococcus thermophilus LMG 18311 3164487 YP_139241.1 CDS divIB NC_006448.1 692094 693218 D cell division protein 692094..693218 Streptococcus thermophilus LMG 18311 3164141 YP_139242.1 CDS ftsA NC_006448.1 693342 694718 D cell division protein 693342..694718 Streptococcus thermophilus LMG 18311 3164474 YP_139243.1 CDS ftsZ NC_006448.1 694747 696069 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 694747..696069 Streptococcus thermophilus LMG 18311 3165403 YP_139244.1 CDS stu0736 NC_006448.1 696072 696755 D hypothetical protein 696072..696755 Streptococcus thermophilus LMG 18311 3164505 YP_139245.1 CDS stu0737 NC_006448.1 696760 697329 D hypothetical protein 696760..697329 Streptococcus thermophilus LMG 18311 3164448 YP_139246.1 CDS stu0738 NC_006448.1 697333 697590 D hypothetical protein 697333..697590 Streptococcus thermophilus LMG 18311 3165240 YP_139247.1 CDS stu0739 NC_006448.1 697590 698390 D hypothetical protein 697590..698390 Streptococcus thermophilus LMG 18311 3165521 YP_139248.1 CDS divIVA NC_006448.1 698634 699509 D cell division initiation protein 698634..699509 Streptococcus thermophilus LMG 18311 3163946 YP_139249.1 CDS ileS NC_006448.1 699757 702546 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 699757..702546 Streptococcus thermophilus LMG 18311 3164426 YP_139250.1 CDS stu0743 NC_006448.1 702931 703167 R truncated; truncated IS1193 transposase complement(702931..703167) Streptococcus thermophilus LMG 18311 3164665 YP_139251.1 CDS stu0745 NC_006448.1 703761 704972 D hypothetical protein 703761..704972 Streptococcus thermophilus LMG 18311 3164666 YP_139252.2 CDS rpmE2 NC_006448.1 705146 705388 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(705146..705388) Streptococcus thermophilus LMG 18311 3164004 YP_139253.1 CDS apbE NC_006448.1 705494 706432 R thiamine biosynthesis lipoprotein complement(705494..706432) Streptococcus thermophilus LMG 18311 3164667 YP_139254.1 CDS stu0748 NC_006448.1 706413 707357 R hypothetical protein complement(706413..707357) Streptococcus thermophilus LMG 18311 3163820 YP_139255.1 CDS stu0749 NC_006448.1 707438 708256 R YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU complement(707438..708256) Streptococcus thermophilus LMG 18311 3164594 YP_139256.1 CDS add NC_006448.1 708396 709406 D catalyzes the formation of inosine from adenosine; adenosine deaminase 708396..709406 Streptococcus thermophilus LMG 18311 3163947 YP_139257.1 CDS tdk NC_006448.1 709635 710231 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 709635..710231 Streptococcus thermophilus LMG 18311 3163949 YP_139258.1 CDS prfA NC_006448.1 710268 711347 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 710268..711347 Streptococcus thermophilus LMG 18311 3163951 YP_139259.1 CDS hemK NC_006448.1 711344 712177 D protoporphyrinogen oxidase 711344..712177 Streptococcus thermophilus LMG 18311 3163952 YP_139260.1 CDS stu0754 NC_006448.1 712164 712769 D Sua5/YciO/YrdC family protein 712164..712769 Streptococcus thermophilus LMG 18311 3165187 YP_139261.1 CDS glyA NC_006448.1 712864 714114 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 712864..714114 Streptococcus thermophilus LMG 18311 3165188 YP_139262.1 CDS stu0756 NC_006448.1 714121 715098 D hypothetical protein 714121..715098 Streptococcus thermophilus LMG 18311 3164472 YP_139263.1 CDS stu0757 NC_006448.1 715046 715711 D hypothetical protein 715046..715711 Streptococcus thermophilus LMG 18311 3165191 YP_139264.1 CDS stu0758 NC_006448.1 715744 717483 D lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 715744..717483 Streptococcus thermophilus LMG 18311 3164709 YP_139265.1 CDS stu0759 NC_006448.1 717350 719221 D lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein 717350..719221 Streptococcus thermophilus LMG 18311 3165509 YP_139266.1 CDS dltX NC_006448.1 719263 719529 D component involved in D-alanylation of teichoic acids 719263..719529 Streptococcus thermophilus LMG 18311 3164714 YP_139267.1 CDS dltA NC_006448.1 719538 721088 D transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 719538..721088 Streptococcus thermophilus LMG 18311 3165168 YP_139268.1 CDS dltB NC_006448.1 721085 722332 D hypothetical protein 721085..722332 Streptococcus thermophilus LMG 18311 3164715 YP_139269.1 CDS dltC NC_006448.1 722350 722589 D D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 722350..722589 Streptococcus thermophilus LMG 18311 3165458 YP_139270.1 CDS dltD NC_006448.1 722582 723850 D hypothetical protein 722582..723850 Streptococcus thermophilus LMG 18311 3165141 YP_139271.1 CDS stu0765 NC_006448.1 723903 724121 R truncated; hypothetical protein complement(723903..724121) Streptococcus thermophilus LMG 18311 3164891 YP_139272.1 CDS stu0766 NC_006448.1 724185 724391 R truncated; hypothetical protein complement(724185..724391) Streptococcus thermophilus LMG 18311 3164955 YP_139273.1 CDS stu0767 NC_006448.1 724405 724740 R truncated; hypothetical protein complement(724405..724740) Streptococcus thermophilus LMG 18311 3164892 YP_139274.1 CDS stu0768 NC_006448.1 724799 724981 R truncated; hypothetical protein complement(724799..724981) Streptococcus thermophilus LMG 18311 3164563 YP_139275.1 CDS stu0769 NC_006448.1 724974 725252 R truncated; hypothetical protein complement(724974..725252) Streptococcus thermophilus LMG 18311 3164893 YP_139276.1 CDS pacL1 NC_006448.1 725450 728086 R Ca2+, Mn2+-P-type ATPase complement(725450..728086) Streptococcus thermophilus LMG 18311 3165428 YP_139277.1 CDS pabB NC_006448.1 728263 729981 R para-aminobenzoate synthetase component I complement(728263..729981) Streptococcus thermophilus LMG 18311 3163740 YP_139278.1 CDS stu0784 NC_006448.1 730128 730463 D phage protein 730128..730463 Streptococcus thermophilus LMG 18311 3164829 YP_139279.1 CDS metE NC_006448.1 730752 733040 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 730752..733040 Streptococcus thermophilus LMG 18311 3164830 YP_139280.1 CDS metF NC_006448.1 733169 734104 D 5,10-methylenetetrahydrofolate reductase 733169..734104 Streptococcus thermophilus LMG 18311 3164552 YP_139281.1 CDS pgmA NC_006448.1 734244 735962 R phosphoglucomutase complement(734244..735962) Streptococcus thermophilus LMG 18311 3164602 YP_139282.1 CDS stu0788 NC_006448.1 736045 736620 R hypothetical protein complement(736045..736620) Streptococcus thermophilus LMG 18311 3164603 YP_139283.1 CDS dfp1 NC_006448.1 736645 737220 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(736645..737220) Streptococcus thermophilus LMG 18311 3164604 YP_139284.1 CDS dfp2 NC_006448.1 737183 737866 R phosphopantothenate--cysteine ligase complement(737183..737866) Streptococcus thermophilus LMG 18311 3164605 YP_139285.1 CDS fhs NC_006448.1 738060 739730 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 738060..739730 Streptococcus thermophilus LMG 18311 3164606 YP_139286.1 CDS stu0792 NC_006448.1 740054 740452 D truncated; response regulator, truncated 740054..740452 Streptococcus thermophilus LMG 18311 3164303 YP_139287.1 CDS stu0793 NC_006448.1 740580 740879 D truncated; sensor histidine kinase, truncated 740580..740879 Streptococcus thermophilus LMG 18311 3165554 YP_139288.1 CDS stu0794 NC_006448.1 740957 741280 D truncated; sensor histidine kinase, truncated 740957..741280 Streptococcus thermophilus LMG 18311 3165179 YP_139289.1 CDS stu0795 NC_006448.1 741282 741998 D truncated; sensor histidine kinase, truncated 741282..741998 Streptococcus thermophilus LMG 18311 3164550 YP_139290.1 CDS tnpSth1 NC_006448.1 742068 742937 R IS3 familytransposase orf2 complement(742068..742937) Streptococcus thermophilus LMG 18311 3165089 YP_139291.1 CDS tnpSth1 NC_006448.1 742952 743692 R IS3 familytransposase orf1 complement(742952..743692) Streptococcus thermophilus LMG 18311 3165203 YP_139292.2 CDS rpsT NC_006448.1 743774 744010 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(743774..744010) Streptococcus thermophilus LMG 18311 3165183 YP_139293.1 CDS coaA NC_006448.1 744079 744999 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(744079..744999) Streptococcus thermophilus LMG 18311 3165184 YP_139294.1 CDS stu0800 NC_006448.1 745272 745913 D hypothetical protein 745272..745913 Streptococcus thermophilus LMG 18311 3165381 YP_139295.1 CDS stu0801 NC_006448.1 745929 746111 D truncated; pyrimidine-nucleoside phosphorylase, truncated 745929..746111 Streptococcus thermophilus LMG 18311 3165043 YP_139296.1 CDS stu0802 NC_006448.1 746193 746363 D truncated; pyrimidine-nucleoside phosphorylase, truncated 746193..746363 Streptococcus thermophilus LMG 18311 3163939 YP_139297.1 CDS stu0803 NC_006448.1 746344 746730 D truncated; pyrimidine-nucleoside phosphorylase, truncated 746344..746730 Streptococcus thermophilus LMG 18311 3163941 YP_139298.1 CDS stu0804 NC_006448.1 746748 747143 D truncated; pyrimidine-nucleoside phosphorylase, truncated 746748..747143 Streptococcus thermophilus LMG 18311 3165479 YP_139299.1 CDS stu0806 NC_006448.1 747483 747878 D truncated; deoxyribose-phosphate aldolase, truncated 747483..747878 Streptococcus thermophilus LMG 18311 3165548 YP_139300.1 CDS cdd NC_006448.1 747853 748197 D cytidine deaminase 747853..748197 Streptococcus thermophilus LMG 18311 3165534 YP_139301.1 CDS stu0808 NC_006448.1 748269 749396 D hypothetical protein 748269..749396 Streptococcus thermophilus LMG 18311 3163943 YP_139302.1 CDS stu0809 NC_006448.1 749495 751048 D carbohydrate ABC uptake transporter ATP-binding protein 749495..751048 Streptococcus thermophilus LMG 18311 3163944 YP_139303.1 CDS stu0810 NC_006448.1 751041 752108 D carbohydrate ABC uptake transporter membrane-spanning protein 751041..752108 Streptococcus thermophilus LMG 18311 3164340 YP_139304.1 CDS stu0811 NC_006448.1 752110 753066 D carbohydrate ABC uptake transporter membrane-spanning protein 752110..753066 Streptococcus thermophilus LMG 18311 3163963 YP_139305.1 CDS stu0812 NC_006448.1 753170 753805 R hypothetical protein complement(753170..753805) Streptococcus thermophilus LMG 18311 3165120 YP_139306.1 CDS stu0813 NC_006448.1 753868 755541 D unwinds DNA; ATP-dependent DNA helicase 753868..755541 Streptococcus thermophilus LMG 18311 3163966 YP_139307.1 CDS stu0814 NC_006448.1 755605 756387 D truncated; ATP-dependent DNA helicase, truncated 755605..756387 Streptococcus thermophilus LMG 18311 3164055 YP_139308.1 CDS stu0815 NC_006448.1 756583 757014 D hypothetical protein 756583..757014 Streptococcus thermophilus LMG 18311 3164600 YP_139309.1 CDS aspC1 NC_006448.1 757019 758200 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 757019..758200 Streptococcus thermophilus LMG 18311 3164601 YP_139310.1 CDS asnC NC_006448.1 758237 759583 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 758237..759583 Streptococcus thermophilus LMG 18311 3163778 YP_139311.1 CDS stu0819 NC_006448.1 759610 760017 D hypothetical protein 759610..760017 Streptococcus thermophilus LMG 18311 3164413 YP_139312.1 CDS stu0821 NC_006448.1 760245 760463 R truncated; truncated IS1193 transposase complement(760245..760463) Streptococcus thermophilus LMG 18311 3164548 YP_139313.1 CDS stu0822 NC_006448.1 760551 760757 R truncated; truncated IS1193 transposase complement(760551..760757) Streptococcus thermophilus LMG 18311 3163780 YP_139314.1 CDS stu0823 NC_006448.1 760754 760891 R truncated; truncated IS1193 transposase complement(760754..760891) Streptococcus thermophilus LMG 18311 3164922 YP_139315.1 CDS stu0824 NC_006448.1 761099 761479 D translation initiation inhibitor 761099..761479 Streptococcus thermophilus LMG 18311 3164924 YP_139316.1 CDS stu0825 NC_006448.1 761653 762306 D hypothetical protein 761653..762306 Streptococcus thermophilus LMG 18311 3164923 YP_139317.1 CDS ptpS NC_006448.1 762306 762749 D 6-pyruvoyl tetrahydrobiopterin synthase 762306..762749 Streptococcus thermophilus LMG 18311 3164925 YP_139318.1 CDS stu0827 NC_006448.1 762742 763458 D coenzyme PQQ synthesis protein 762742..763458 Streptococcus thermophilus LMG 18311 3164937 YP_139319.1 CDS stu0828 NC_006448.1 763533 764069 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 763533..764069 Streptococcus thermophilus LMG 18311 3164906 YP_139320.1 CDS stu0829 NC_006448.1 764889 765077 D hypothetical protein 764889..765077 Streptococcus thermophilus LMG 18311 3164908 YP_139321.1 CDS stu0830 NC_006448.1 765282 766052 D hypothetical protein 765282..766052 Streptococcus thermophilus LMG 18311 3164642 YP_139322.1 CDS stu0831 NC_006448.1 766033 766923 D hypothetical protein 766033..766923 Streptococcus thermophilus LMG 18311 3164643 YP_139323.1 CDS stu0832 NC_006448.1 766920 767894 D hypothetical protein 766920..767894 Streptococcus thermophilus LMG 18311 3164644 YP_139324.1 CDS stu0833 NC_006448.1 767891 768802 D hypothetical protein 767891..768802 Streptococcus thermophilus LMG 18311 3164645 YP_139325.1 CDS stu0835 NC_006448.1 769091 769570 D truncated; dipeptidase, truncated 769091..769570 Streptococcus thermophilus LMG 18311 3164646 YP_139326.1 CDS stu0836 NC_006448.1 769577 769813 D truncated; dipeptidase, truncated 769577..769813 Streptococcus thermophilus LMG 18311 3164647 YP_139327.1 CDS cspA NC_006448.1 770104 770313 D cold shock protein A 770104..770313 Streptococcus thermophilus LMG 18311 3164660 YP_139328.1 CDS cspB NC_006448.1 770527 770793 D cold shock protein B 770527..770793 Streptococcus thermophilus LMG 18311 3165368 YP_139329.1 CDS tnp1191 NC_006448.1 771091 772299 D IS1191 transposase 771091..772299 Streptococcus thermophilus LMG 18311 3164661 YP_139330.1 CDS copB NC_006448.1 772420 774627 R Cu2+-Cu+-Ag+-P-type ATPase complement(772420..774627) Streptococcus thermophilus LMG 18311 3164662 YP_139331.1 CDS stu0841 NC_006448.1 774818 775009 R truncated; truncated IS1191 transposase complement(774818..775009) Streptococcus thermophilus LMG 18311 3164663 YP_139332.1 CDS stu0842 NC_006448.1 775051 775614 R truncated; truncated IS1191 transposase complement(775051..775614) Streptococcus thermophilus LMG 18311 3164142 YP_139333.1 CDS stu0843 NC_006448.1 775647 776006 R truncated; truncated IS1191 transposase complement(775647..776006) Streptococcus thermophilus LMG 18311 3164755 YP_139334.1 CDS stu0844 NC_006448.1 776053 777078 R truncated; type I restriction-modification system restriction subunit, truncated complement(776053..777078) Streptococcus thermophilus LMG 18311 3163934 YP_139335.1 CDS cysM2 NC_006448.1 777824 778735 D cysteine synthase 777824..778735 Streptococcus thermophilus LMG 18311 3164529 YP_139336.1 CDS metB2 NC_006448.1 778757 779941 D cystathionine beta-lyase 778757..779941 Streptococcus thermophilus LMG 18311 3165105 YP_139337.1 CDS cysE2 NC_006448.1 779883 780464 D serine acetyltransferase 779883..780464 Streptococcus thermophilus LMG 18311 3164731 YP_139338.1 CDS tnp1191 NC_006448.1 780961 782169 D IS1191 transposase 780961..782169 Streptococcus thermophilus LMG 18311 3163830 YP_139339.1 CDS stu0850 NC_006448.1 782426 782572 R truncated; type I restriction-modification system specificty subunit, truncated complement(782426..782572) Streptococcus thermophilus LMG 18311 3165087 YP_139340.1 CDS stu0851 NC_006448.1 782642 782968 R truncated; type I restriction-modification system specificty subunit, truncated complement(782642..782968) Streptococcus thermophilus LMG 18311 3163823 YP_139341.1 CDS stu0852 NC_006448.1 782965 783597 R truncated; type I restriction-modification system methyltransferase subunit, truncated complement(782965..783597) Streptococcus thermophilus LMG 18311 3165311 YP_139342.1 CDS stu0855 NC_006448.1 784076 784963 D glucose/ribose porter (GRP) family protein 784076..784963 Streptococcus thermophilus LMG 18311 3165023 YP_139343.1 CDS stu0856 NC_006448.1 785579 785773 D truncated; type I restriction-modification system restriction subunit, truncated 785579..785773 Streptococcus thermophilus LMG 18311 3165370 YP_139344.1 CDS stu0857 NC_006448.1 785953 786285 D truncated; type I restriction-modification system methyltransferase subunit, truncated 785953..786285 Streptococcus thermophilus LMG 18311 3163922 YP_139345.1 CDS stu0859 NC_006448.1 786573 787238 R hypothetical protein complement(786573..787238) Streptococcus thermophilus LMG 18311 3164068 YP_139346.1 CDS adcA NC_006448.1 787447 788991 D zinc (Zn2+) ABC uptake transporter substrate binding protein 787447..788991 Streptococcus thermophilus LMG 18311 3163925 YP_139347.1 CDS stu0861 NC_006448.1 789209 789607 D hypothetical protein 789209..789607 Streptococcus thermophilus LMG 18311 3165492 YP_139348.1 CDS stu0863 NC_006448.1 790120 790419 R truncated; hypothetical protein complement(790120..790419) Streptococcus thermophilus LMG 18311 3165027 YP_139349.1 CDS stu0864 NC_006448.1 790359 790838 R truncated; hypothetical protein complement(790359..790838) Streptococcus thermophilus LMG 18311 3164572 YP_139350.1 CDS stu0865 NC_006448.1 790813 791118 R truncated; hypothetical protein complement(790813..791118) Streptococcus thermophilus LMG 18311 3165028 YP_139351.1 CDS stu0866 NC_006448.1 791093 791221 R truncated; hypothetical protein complement(791093..791221) Streptococcus thermophilus LMG 18311 3164367 YP_139352.1 CDS stu0868 NC_006448.1 791539 792546 R hypothetical protein complement(791539..792546) Streptococcus thermophilus LMG 18311 3164292 YP_139353.1 CDS mur2 NC_006448.1 792954 793433 D peptidoglycan hydrolase 792954..793433 Streptococcus thermophilus LMG 18311 3165207 YP_139354.1 CDS stu0870 NC_006448.1 793445 793663 D truncated; hypothetical protein 793445..793663 Streptococcus thermophilus LMG 18311 3164228 YP_139355.1 CDS stu0871 NC_006448.1 793667 794221 D truncated; hypothetical protein 793667..794221 Streptococcus thermophilus LMG 18311 3164057 YP_139356.1 CDS cmhR NC_006448.1 794419 795327 R metCcysK operon transcriptional activator complement(794419..795327) Streptococcus thermophilus LMG 18311 3164056 YP_139357.1 CDS glmS NC_006448.1 795534 797342 D isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 795534..797342 Streptococcus thermophilus LMG 18311 3164154 YP_139358.1 CDS phnA NC_006448.1 797460 797789 D PhnA-like protein 797460..797789 Streptococcus thermophilus LMG 18311 3163996 YP_139359.1 CDS stu0875 NC_006448.1 797983 798624 D polar amino acid ABC uptake transporter membrane-spanning protein 797983..798624 Streptococcus thermophilus LMG 18311 3163954 YP_139360.1 CDS stu0876 NC_006448.1 798633 799262 D polar amino acid ABC uptake transporter ATP-binding protein 798633..799262 Streptococcus thermophilus LMG 18311 3164541 YP_139361.1 CDS stu0877 NC_006448.1 799275 800126 D polar amino acid ABC uptake transporter substrate binding protein 799275..800126 Streptococcus thermophilus LMG 18311 3164197 YP_139362.1 CDS stu0879 NC_006448.1 800589 801410 D truncated; SOS responce UmuC protein, truncated 800589..801410 Streptococcus thermophilus LMG 18311 3164427 YP_139363.1 CDS stu0880 NC_006448.1 802182 802535 D truncated; alcohol dehydrogenase 802182..802535 Streptococcus thermophilus LMG 18311 3164618 YP_139364.1 CDS stu0881 NC_006448.1 802549 802680 D truncated; alcohol dehydrogenase 802549..802680 Streptococcus thermophilus LMG 18311 3164428 YP_139365.1 CDS stu0882 NC_006448.1 802726 803214 D truncated; alcohol dehydrogenase 802726..803214 Streptococcus thermophilus LMG 18311 3164430 YP_139366.1 CDS sthIR NC_006448.1 803838 806624 R DNA endonuclease, type III restriction and modification system complement(803838..806624) Streptococcus thermophilus LMG 18311 3164433 YP_139367.1 CDS sthIM NC_006448.1 806626 808551 R type III restriction-modification system methylation subunit complement(806626..808551) Streptococcus thermophilus LMG 18311 3164434 YP_139368.1 CDS guaA NC_006448.1 808774 810357 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(808774..810357) Streptococcus thermophilus LMG 18311 3164528 YP_139369.1 CDS stu0887 NC_006448.1 810505 811203 D GntR family transcriptional regulator 810505..811203 Streptococcus thermophilus LMG 18311 3164188 YP_139370.1 CDS stu0888 NC_006448.1 811270 811602 D DNA-binding protein 811270..811602 Streptococcus thermophilus LMG 18311 3164009 YP_139371.1 CDS ffh NC_006448.1 811635 813197 D signal recognition particle 811635..813197 Streptococcus thermophilus LMG 18311 3164190 YP_139372.1 CDS stu0890 NC_006448.1 813239 813826 D hypothetical protein 813239..813826 Streptococcus thermophilus LMG 18311 3164192 YP_139373.1 CDS stu0891 NC_006448.1 813850 814365 D biotin repressor family transcriptional regulator 813850..814365 Streptococcus thermophilus LMG 18311 3165340 YP_139374.1 CDS stu0892 NC_006448.1 814460 815149 D transcriptional regulator 814460..815149 Streptococcus thermophilus LMG 18311 3164195 YP_139375.1 CDS rbgA NC_006448.1 815277 816131 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 815277..816131 Streptococcus thermophilus LMG 18311 3164832 YP_139376.1 CDS rnhB NC_006448.1 816103 816885 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 816103..816885 Streptococcus thermophilus LMG 18311 3164833 YP_139377.1 CDS stu0895 NC_006448.1 816896 817816 D transcriptional regulator 816896..817816 Streptococcus thermophilus LMG 18311 3164835 YP_139378.1 CDS dprA NC_006448.1 817884 818723 D Smf family DNA processing protein 817884..818723 Streptococcus thermophilus LMG 18311 3164834 YP_139379.1 CDS topA NC_006448.1 818891 821035 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 818891..821035 Streptococcus thermophilus LMG 18311 3165030 YP_139380.1 CDS tnpSth1 NC_006448.1 821099 821968 R IS3 familytransposase orf2 complement(821099..821968) Streptococcus thermophilus LMG 18311 3164837 YP_139381.1 CDS tnpSth1 NC_006448.1 821983 822723 R IS3 familytransposase orf1 complement(821983..822723) Streptococcus thermophilus LMG 18311 3165024 YP_139382.1 CDS stu0900 NC_006448.1 822839 823663 D hypothetical protein 822839..823663 Streptococcus thermophilus LMG 18311 3165473 YP_139383.1 CDS rr04 NC_006448.1 823699 824358 D response regulator 823699..824358 Streptococcus thermophilus LMG 18311 3164655 YP_139384.1 CDS hk04 NC_006448.1 824331 825743 D sensor histidine kinase 824331..825743 Streptococcus thermophilus LMG 18311 3165611 YP_139385.1 CDS gid NC_006448.1 825844 827187 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 825844..827187 Streptococcus thermophilus LMG 18311 3164280 YP_139386.1 CDS stu0904 NC_006448.1 827190 827414 R truncated; hypothetical protein complement(827190..827414) Streptococcus thermophilus LMG 18311 3165616 YP_139387.1 CDS stu0905 NC_006448.1 827451 828242 R truncated; hypothetical protein complement(827451..828242) Streptococcus thermophilus LMG 18311 3164223 YP_139388.1 CDS ndk NC_006448.1 828553 828981 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 828553..828981 Streptococcus thermophilus LMG 18311 3164804 YP_139389.1 CDS stu0907 NC_006448.1 828971 829276 D hypothetical protein 828971..829276 Streptococcus thermophilus LMG 18311 3164099 YP_139390.1 CDS stu0909 NC_006448.1 829457 829828 D truncated; acetoin reductase, truncated 829457..829828 Streptococcus thermophilus LMG 18311 3164759 YP_139391.1 CDS stu0910 NC_006448.1 830104 830250 D truncated; acetoin reductase, truncated 830104..830250 Streptococcus thermophilus LMG 18311 3165114 YP_139392.1 CDS lepA NC_006448.1 830638 832470 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 830638..832470 Streptococcus thermophilus LMG 18311 3165068 YP_139393.1 CDS stu0912 NC_006448.1 832876 833217 D hypothetical protein 832876..833217 Streptococcus thermophilus LMG 18311 3164989 YP_139394.1 CDS stu0913 NC_006448.1 833152 833568 R hypothetical protein complement(833152..833568) Streptococcus thermophilus LMG 18311 3165123 YP_139395.1 CDS stu0914 NC_006448.1 833656 833778 D truncated; hypothetical protein 833656..833778 Streptococcus thermophilus LMG 18311 3164951 YP_139396.1 CDS stu0915 NC_006448.1 833841 834086 D truncated; hypothetical protein 833841..834086 Streptococcus thermophilus LMG 18311 3164717 YP_139397.1 CDS stu0916 NC_006448.1 834195 834530 D transcriptional regulator 834195..834530 Streptococcus thermophilus LMG 18311 3164300 YP_139398.1 CDS stu0917 NC_006448.1 834855 835721 D MutR family transcriptional regulator 834855..835721 Streptococcus thermophilus LMG 18311 3164209 YP_139399.1 CDS stu0918 NC_006448.1 835781 836581 D hypothetical protein 835781..836581 Streptococcus thermophilus LMG 18311 3164289 YP_139400.1 CDS stu0919 NC_006448.1 836626 836790 D hypothetical protein 836626..836790 Streptococcus thermophilus LMG 18311 3164510 YP_139401.1 CDS stu0920 NC_006448.1 836992 838089 D metallo cofactor biosynthesis protein 836992..838089 Streptococcus thermophilus LMG 18311 3165137 YP_139402.1 CDS speB NC_006448.1 838086 838829 D agmatinase 838086..838829 Streptococcus thermophilus LMG 18311 3164823 YP_139403.1 CDS stu0922 NC_006448.1 838860 840008 D hypothetical protein 838860..840008 Streptococcus thermophilus LMG 18311 3165155 YP_139404.1 CDS als NC_006448.1 840256 841938 D catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 840256..841938 Streptococcus thermophilus LMG 18311 3163821 YP_139405.1 CDS aldB NC_006448.1 841954 842673 D alpha-acetolactate decarboxylase 841954..842673 Streptococcus thermophilus LMG 18311 3164525 YP_139406.1 CDS stu0925 NC_006448.1 842852 843835 R truncated; truncated IS1193 transposase complement(842852..843835) Streptococcus thermophilus LMG 18311 3165052 YP_139407.1 CDS stu0926 NC_006448.1 843822 843983 R truncated; truncated IS1193 transposase complement(843822..843983) Streptococcus thermophilus LMG 18311 3164258 YP_139408.1 CDS stu0927 NC_006448.1 844200 844394 R truncated; ABC transporter membrane-spanning protein, truncated complement(844200..844394) Streptococcus thermophilus LMG 18311 3163863 YP_139409.1 CDS stu0928 NC_006448.1 844372 844944 R truncated; ABC transporter membrane-spanning protein, truncated complement(844372..844944) Streptococcus thermophilus LMG 18311 3165175 YP_139410.1 CDS stu0929 NC_006448.1 845166 845918 D short chain dehydrogenase/reductase family oxidoreductase 845166..845918 Streptococcus thermophilus LMG 18311 3163848 YP_139411.1 CDS stu0930 NC_006448.1 846095 846307 R hypothetical protein complement(846095..846307) Streptococcus thermophilus LMG 18311 3163870 YP_139412.1 CDS stu0931 NC_006448.1 846346 846885 R TetR family transcriptional regulator complement(846346..846885) Streptococcus thermophilus LMG 18311 3165026 YP_139413.1 CDS stu0932 NC_006448.1 847019 847915 D cation diffusion facilitor (CDF) family protein 847019..847915 Streptococcus thermophilus LMG 18311 3165093 YP_139414.1 CDS stu0934 NC_006448.1 848027 848338 D truncated; ferrochelatase 848027..848338 Streptococcus thermophilus LMG 18311 3164449 YP_139415.1 CDS stu0935 NC_006448.1 848339 849121 D truncated; ferrochelatase 848339..849121 Streptococcus thermophilus LMG 18311 3165054 YP_139416.1 CDS adhB NC_006448.1 849218 850255 D alcohol dehydrogenase 849218..850255 Streptococcus thermophilus LMG 18311 3165065 YP_139417.1 CDS stu0937 NC_006448.1 850669 850848 D truncated; hypothetical protein 850669..850848 Streptococcus thermophilus LMG 18311 3165037 YP_139418.1 CDS stu0938 NC_006448.1 850927 851376 D truncated; hypothetical protein 850927..851376 Streptococcus thermophilus LMG 18311 3165606 YP_139419.1 CDS stu0940 NC_006448.1 851838 852290 D hypothetical protein 851838..852290 Streptococcus thermophilus LMG 18311 3164182 YP_139420.1 CDS stu0941 NC_006448.1 852636 853400 D phosphorylase Pnp/Udp family protein 852636..853400 Streptococcus thermophilus LMG 18311 3164534 YP_139421.1 CDS stu0942 NC_006448.1 853462 854109 R phosphatase complement(853462..854109) Streptococcus thermophilus LMG 18311 3164331 YP_139422.1 CDS stu0943 NC_006448.1 854385 854516 D truncated; ferrichrome ABC transporter substrate-binding protein 854385..854516 Streptococcus thermophilus LMG 18311 3163737 YP_139423.1 CDS stu0944 NC_006448.1 854559 854834 D hypothetical protein 854559..854834 Streptococcus thermophilus LMG 18311 3165067 YP_139424.1 CDS stu0946 NC_006448.1 855112 855378 R truncated; hypothetical protein complement(855112..855378) Streptococcus thermophilus LMG 18311 3164231 YP_139425.1 CDS stu0947 NC_006448.1 855375 855932 R truncated; hypothetical protein complement(855375..855932) Streptococcus thermophilus LMG 18311 3164521 YP_139426.1 CDS stu0948 NC_006448.1 855974 856222 R truncated; hypothetical protein complement(855974..856222) Streptococcus thermophilus LMG 18311 3164687 YP_139427.1 CDS stu0949 NC_006448.1 856483 856692 D hypothetical protein 856483..856692 Streptococcus thermophilus LMG 18311 3165069 YP_139428.1 CDS fbp NC_006448.1 857068 858726 R fibronectin-binding protein-like protein A complement(857068..858726) Streptococcus thermophilus LMG 18311 3165079 YP_139429.1 CDS stu0951 NC_006448.1 859044 859601 D hypothetical protein 859044..859601 Streptococcus thermophilus LMG 18311 3164752 YP_139430.1 CDS thiJ NC_006448.1 859868 860416 D 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme 859868..860416 Streptococcus thermophilus LMG 18311 3165290 YP_139431.1 CDS pyrK NC_006448.1 860658 861461 D responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 860658..861461 Streptococcus thermophilus LMG 18311 3165329 YP_139432.1 CDS pyrDb NC_006448.1 861480 862427 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 861480..862427 Streptococcus thermophilus LMG 18311 3164506 YP_139433.1 CDS stu0956 NC_006448.1 862566 863189 D hypothetical protein 862566..863189 Streptococcus thermophilus LMG 18311 3165546 YP_139434.1 CDS stu0957 NC_006448.1 863174 863569 D hypothetical protein 863174..863569 Streptococcus thermophilus LMG 18311 3164878 YP_139435.1 CDS stu0958 NC_006448.1 863569 863898 D hypothetical protein 863569..863898 Streptococcus thermophilus LMG 18311 3164881 YP_139436.1 CDS stu0959 NC_006448.1 864454 865185 D hypothetical protein 864454..865185 Streptococcus thermophilus LMG 18311 3164455 YP_139437.1 CDS stu0960 NC_006448.1 865166 867442 D hypothetical protein 865166..867442 Streptococcus thermophilus LMG 18311 3164305 YP_139438.1 CDS stu0961 NC_006448.1 867446 867826 D hypothetical protein 867446..867826 Streptococcus thermophilus LMG 18311 3164157 YP_139439.1 CDS stu0962 NC_006448.1 867826 868488 D hypothetical protein 867826..868488 Streptococcus thermophilus LMG 18311 3164164 YP_139440.1 CDS stu0963 NC_006448.1 868490 869389 D hypothetical protein 868490..869389 Streptococcus thermophilus LMG 18311 3164129 YP_139441.1 CDS stu0964 NC_006448.1 869392 870465 D hypothetical protein 869392..870465 Streptococcus thermophilus LMG 18311 3164354 YP_139442.1 CDS stu0965 NC_006448.1 870620 870736 D truncated; hypothetical protein 870620..870736 Streptococcus thermophilus LMG 18311 3165041 YP_139443.1 CDS stu0966 NC_006448.1 870767 871795 D truncated; hypothetical protein 870767..871795 Streptococcus thermophilus LMG 18311 3165146 YP_139444.1 CDS pyrF NC_006448.1 871995 872690 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 871995..872690 Streptococcus thermophilus LMG 18311 3163874 YP_139445.1 CDS pyrE NC_006448.1 872779 873408 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 872779..873408 Streptococcus thermophilus LMG 18311 3164313 YP_139446.1 CDS stu0969 NC_006448.1 873649 874056 D truncated; amidase 873649..874056 Streptococcus thermophilus LMG 18311 3164265 YP_139447.1 CDS dtpT NC_006448.1 874107 875558 R di- or tripeptide:H+ symporter complement(874107..875558) Streptococcus thermophilus LMG 18311 3164310 YP_139448.1 CDS tnp1239 NC_006448.1 875897 876937 D IS1239 transposase 875897..876937 Streptococcus thermophilus LMG 18311 3163853 YP_139449.1 CDS stu0973 NC_006448.1 877223 877825 D truncated; amidase 877223..877825 Streptococcus thermophilus LMG 18311 3164097 YP_139450.1 CDS stu0974 NC_006448.1 877914 878348 D truncated; amino acid ABC transporter substrate-binding protein 877914..878348 Streptococcus thermophilus LMG 18311 3164328 YP_139451.1 CDS stu0975 NC_006448.1 878368 878727 D truncated; amino acid ABC transporter substrate-binding protein 878368..878727 Streptococcus thermophilus LMG 18311 3164566 YP_139452.1 CDS stu0976 NC_006448.1 878866 879279 D truncated; amino acid ABC uptake transporter membrane-spanning protein, truncated 878866..879279 Streptococcus thermophilus LMG 18311 3164488 YP_139453.1 CDS stu0977 NC_006448.1 879249 879437 D truncated; amino acid ABC uptake transporter membrane-spanning protein, truncated 879249..879437 Streptococcus thermophilus LMG 18311 3164450 YP_139454.1 CDS stu0978 NC_006448.1 879567 879800 D hypothetical protein 879567..879800 Streptococcus thermophilus LMG 18311 3164267 YP_139455.1 CDS stu0979 NC_006448.1 879874 881340 D 5'-nucleotidase 879874..881340 Streptococcus thermophilus LMG 18311 3164422 YP_139456.1 CDS stu0980 NC_006448.1 881351 881638 D hypothetical protein 881351..881638 Streptococcus thermophilus LMG 18311 3164477 YP_139457.1 CDS stu0981 NC_006448.1 881848 882456 R truncated; AraC family transcriptional regulator complement(881848..882456) Streptococcus thermophilus LMG 18311 3165078 YP_139458.1 CDS stu0982 NC_006448.1 882681 882815 R truncated; AraC family transcriptional regulator complement(882681..882815) Streptococcus thermophilus LMG 18311 3163921 YP_139459.1 CDS trmE NC_006448.1 882931 884301 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(882931..884301) Streptococcus thermophilus LMG 18311 3163882 YP_139460.1 CDS dagA NC_006448.1 884430 885773 R alanine (or glycine):Na+ symporter complement(884430..885773) Streptococcus thermophilus LMG 18311 3163974 YP_139461.1 CDS pcrA NC_006448.1 886271 888598 D ATP-dependent DNA helicase 886271..888598 Streptococcus thermophilus LMG 18311 3164003 YP_139462.1 CDS cysD NC_006448.1 888686 889999 D O-acetylhomoserine sulfhydrylase 888686..889999 Streptococcus thermophilus LMG 18311 3164451 YP_139463.1 CDS stu0988 NC_006448.1 890060 890401 D truncated; hypothetical protein 890060..890401 Streptococcus thermophilus LMG 18311 3164285 YP_139464.1 CDS stu0989 NC_006448.1 890447 890815 D truncated; hypothetical protein 890447..890815 Streptococcus thermophilus LMG 18311 3163741 YP_139465.1 CDS tpx NC_006448.1 890880 891374 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 890880..891374 Streptococcus thermophilus LMG 18311 3163746 YP_139466.1 CDS hsdS2 NC_006448.1 891497 892117 D type I restriction-modification system specificty subunit 891497..892117 Streptococcus thermophilus LMG 18311 3165451 YP_139467.1 CDS stu0992 NC_006448.1 892138 892341 D hypothetical protein 892138..892341 Streptococcus thermophilus LMG 18311 3164160 YP_139468.1 CDS stu0993 NC_006448.1 892355 893140 D truncated; hypothetical protein 892355..893140 Streptococcus thermophilus LMG 18311 3165057 YP_139469.1 CDS stu0994 NC_006448.1 893515 893670 D truncated; hypothetical protein 893515..893670 Streptococcus thermophilus LMG 18311 3164101 YP_139470.1 CDS truB NC_006448.1 893792 894673 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 893792..894673 Streptococcus thermophilus LMG 18311 3164162 YP_139471.1 CDS ribC NC_006448.1 894670 895581 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 894670..895581 Streptococcus thermophilus LMG 18311 3164865 YP_139472.1 CDS spxA NC_006448.1 895652 896065 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 895652..896065 Streptococcus thermophilus LMG 18311 3165055 YP_139473.1 CDS stu0998 NC_006448.1 896058 896339 D hypothetical protein 896058..896339 Streptococcus thermophilus LMG 18311 3164512 YP_139474.1 CDS suhB NC_006448.1 896329 897096 D inositol monophosphatase 896329..897096 Streptococcus thermophilus LMG 18311 3165127 YP_139475.1 CDS stu1000 NC_006448.1 897148 898488 D rRNA methyltransferase 897148..898488 Streptococcus thermophilus LMG 18311 3163975 YP_139476.1 CDS pstS NC_006448.1 898589 899488 D phosphate ABC uptake transporter substrate binding protein 898589..899488 Streptococcus thermophilus LMG 18311 3164719 YP_139477.1 CDS pstC1 NC_006448.1 899491 900405 D phosphate ABC uptake transporter membrane-spanning protein 899491..900405 Streptococcus thermophilus LMG 18311 3165085 YP_139478.1 CDS pstC2 NC_006448.1 900377 901279 D phosphate ABC uptake transporter membrane-spanning protein 900377..901279 Streptococcus thermophilus LMG 18311 3165131 YP_139479.1 CDS pstB1 NC_006448.1 901290 902093 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 901290..902093 Streptococcus thermophilus LMG 18311 3164544 YP_139480.1 CDS pstB2 NC_006448.1 902106 902864 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 902106..902864 Streptococcus thermophilus LMG 18311 3164712 YP_139481.1 CDS phoU NC_006448.1 902889 903545 D phosphate uptake regulatory protein 902889..903545 Streptococcus thermophilus LMG 18311 3164458 YP_139482.1 CDS pepN NC_006448.1 903679 906219 D lysyl-aminopeptidase, aminopeptidase N 903679..906219 Streptococcus thermophilus LMG 18311 3164246 YP_139483.1 CDS xerS NC_006448.1 906381 907451 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS complement(906381..907451) Streptococcus thermophilus LMG 18311 3164628 YP_139484.1 CDS lplA NC_006448.1 907676 908665 R lipoate-protein ligase complement(907676..908665) Streptococcus thermophilus LMG 18311 3163924 YP_139485.1 CDS stu1010 NC_006448.1 908848 909402 D hypothetical protein 908848..909402 Streptococcus thermophilus LMG 18311 3165355 YP_139486.1 CDS stu1011 NC_006448.1 909471 909899 D hypothetical protein 909471..909899 Streptococcus thermophilus LMG 18311 3164484 YP_139487.1 CDS glgP NC_006448.1 910005 912269 R glycogen phosphorylase complement(910005..912269) Streptococcus thermophilus LMG 18311 3164124 YP_139488.1 CDS malQ NC_006448.1 912271 913779 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(912271..913779) Streptococcus thermophilus LMG 18311 3164871 YP_139489.1 CDS malR NC_006448.1 913963 914967 R maltose operon transcriptional repressor complement(913963..914967) Streptococcus thermophilus LMG 18311 3164990 YP_139490.1 CDS stu1015 NC_006448.1 915314 915454 D truncated; maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated 915314..915454 Streptococcus thermophilus LMG 18311 3164524 YP_139491.1 CDS stu1016 NC_006448.1 915626 916012 D truncated; maltose/maltodextrin ABC uptake transporter substrate-binding protein, truncated 915626..916012 Streptococcus thermophilus LMG 18311 3164439 YP_139492.1 CDS stu1017 NC_006448.1 916026 916706 D truncated; maltose/maltodextrin ABC uptake transporter membrane-spanning protein, truncated 916026..916706 Streptococcus thermophilus LMG 18311 3163738 YP_139493.1 CDS tatA NC_006448.1 917353 917541 R Sec-independent protein translocase protein tatA complement(917353..917541) Streptococcus thermophilus LMG 18311 3164549 YP_139494.1 CDS tatC NC_006448.1 917554 918282 R Sec-independent protein translocase protein tatC complement(917554..918282) Streptococcus thermophilus LMG 18311 3164090 YP_139495.1 CDS stu1022 NC_006448.1 918269 919990 R hypothetical protein complement(918269..919990) Streptococcus thermophilus LMG 18311 3164690 YP_139496.1 CDS stu1023 NC_006448.1 919932 921137 R hypothetical protein complement(919932..921137) Streptococcus thermophilus LMG 18311 3163795 YP_139497.1 CDS stu1024 NC_006448.1 921143 921970 R hypothetical protein complement(921143..921970) Streptococcus thermophilus LMG 18311 3164887 YP_139498.1 CDS fatB NC_006448.1 922277 923323 R iron ABC transporter substrate-binding protein complement(922277..923323) Streptococcus thermophilus LMG 18311 3165213 YP_139499.1 CDS fatA NC_006448.1 923335 924090 R iron compound ABC uptake transporter ATP-binding protein complement(923335..924090) Streptococcus thermophilus LMG 18311 3164808 YP_139500.1 CDS fatC NC_006448.1 924087 925073 R iron compound ABC uptake transporter membrane-spanning protein complement(924087..925073) Streptococcus thermophilus LMG 18311 3165075 YP_139501.1 CDS fatD NC_006448.1 925052 926026 R iron compound ABC uptake transporter membrane-spanning protein complement(925052..926026) Streptococcus thermophilus LMG 18311 3164254 YP_139502.1 CDS stu1029 NC_006448.1 926504 926773 R truncated; alkaline amylopullulanase, truncated complement(926504..926773) Streptococcus thermophilus LMG 18311 3164269 YP_139503.1 CDS stu1031 NC_006448.1 926776 927390 R truncated; alkaline amylopullulanase, truncated complement(926776..927390) Streptococcus thermophilus LMG 18311 3163865 YP_139504.1 CDS stu1032 NC_006448.1 927454 927564 R truncated; alkaline amylopullulanase, truncated complement(927454..927564) Streptococcus thermophilus LMG 18311 3163857 YP_139505.1 CDS stu1033 NC_006448.1 927497 928564 R truncated; alkaline amylopullulanase, truncated complement(927497..928564) Streptococcus thermophilus LMG 18311 3165061 YP_139506.1 CDS stu1034 NC_006448.1 928583 928687 R truncated; alkaline amylopullulanase, truncated complement(928583..928687) Streptococcus thermophilus LMG 18311 3165366 YP_139507.1 CDS tnp1191 NC_006448.1 929095 930183 D IS1191 transposase 929095..930183 Streptococcus thermophilus LMG 18311 3164564 YP_139508.1 CDS stu1041 NC_006448.1 930218 930565 R truncated; UDP-N-acetylglucosamine enolpyruvyl transferase, truncated complement(930218..930565) Streptococcus thermophilus LMG 18311 3164461 YP_139509.1 CDS stu1042 NC_006448.1 930567 931133 R hypothetical protein complement(930567..931133) Streptococcus thermophilus LMG 18311 3164326 YP_139510.1 CDS tyrSE NC_006448.1 931927 932835 R tyrosyl-tRNA synthetase E complement(931927..932835) Streptococcus thermophilus LMG 18311 3165091 YP_139511.1 CDS stu1044 NC_006448.1 933089 933943 D MutR family transcriptional regulator 933089..933943 Streptococcus thermophilus LMG 18311 3164159 YP_139512.1 CDS tnp1193 NC_006448.1 934110 935366 R IS1193 transposase complement(934110..935366) Streptococcus thermophilus LMG 18311 3164440 YP_139513.1 CDS stu1046 NC_006448.1 935851 936246 R truncated; endolysin, truncated complement(935851..936246) Streptococcus thermophilus LMG 18311 3165173 YP_139514.1 CDS stu1047 NC_006448.1 936362 936631 R hypothetical protein complement(936362..936631) Streptococcus thermophilus LMG 18311 3163817 YP_139515.1 CDS acoL NC_006448.1 936948 938702 R acetoin/pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase complement(936948..938702) Streptococcus thermophilus LMG 18311 3164479 YP_139516.1 CDS acoC NC_006448.1 938873 940261 R Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(938873..940261) Streptococcus thermophilus LMG 18311 3163980 YP_139517.1 CDS acoB NC_006448.1 940419 941432 R acetoin dehydrogenase complex, E1 component subunit beta complement(940419..941432) Streptococcus thermophilus LMG 18311 3165156 YP_139518.1 CDS acoA NC_006448.1 941442 942413 R acetoin dehydrogenase complex, E1 component subunit alpha complement(941442..942413) Streptococcus thermophilus LMG 18311 3164108 YP_139519.1 CDS stu1052 NC_006448.1 942903 943211 R truncated; hypothetical protein complement(942903..943211) Streptococcus thermophilus LMG 18311 3164470 YP_139520.1 CDS stu1053 NC_006448.1 943467 943988 R truncated; hypothetical protein complement(943467..943988) Streptococcus thermophilus LMG 18311 3164333 YP_139521.1 CDS pyrC NC_006448.1 944180 945448 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(944180..945448) Streptococcus thermophilus LMG 18311 3164436 YP_139522.1 CDS ung NC_006448.1 945468 946148 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(945468..946148) Streptococcus thermophilus LMG 18311 3165071 YP_139523.1 CDS stu1056 NC_006448.1 946335 947531 D hypothetical protein 946335..947531 Streptococcus thermophilus LMG 18311 3165281 YP_139524.1 CDS stu1057 NC_006448.1 947804 947971 D truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 947804..947971 Streptococcus thermophilus LMG 18311 3165424 YP_139525.1 CDS stu1058 NC_006448.1 947952 948134 D truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 947952..948134 Streptococcus thermophilus LMG 18311 3164016 YP_139526.1 CDS stu1059 NC_006448.1 948156 949097 D truncated; D-alanyl-D-alanine-carboxypeptidase, penicillin-binding protein, truncated 948156..949097 Streptococcus thermophilus LMG 18311 3164716 YP_139527.1 CDS stu1060 NC_006448.1 949137 949988 R phosphoesterase complement(949137..949988) Streptococcus thermophilus LMG 18311 3164702 YP_139528.1 CDS stu1061 NC_006448.1 949985 950473 R hypothetical protein complement(949985..950473) Streptococcus thermophilus LMG 18311 3164730 YP_139529.1 CDS stu1062 NC_006448.1 950608 952185 R hypothetical protein complement(950608..952185) Streptococcus thermophilus LMG 18311 3165598 YP_139530.1 CDS stu1063 NC_006448.1 952203 952487 R hypothetical protein complement(952203..952487) Streptococcus thermophilus LMG 18311 3164797 YP_139531.1 CDS stu1064 NC_006448.1 952735 952965 R truncated; 6-phospho-beta-glucosidase complement(952735..952965) Streptococcus thermophilus LMG 18311 3164042 YP_139532.1 CDS stu1065 NC_006448.1 952962 953207 R truncated; 6-phospho-beta-glucosidase complement(952962..953207) Streptococcus thermophilus LMG 18311 3164561 YP_139533.1 CDS stu1066 NC_006448.1 953243 953779 R truncated; 6-phospho-beta-glucosidase complement(953243..953779) Streptococcus thermophilus LMG 18311 3165325 YP_139534.1 CDS stu1067 NC_006448.1 953806 954003 R truncated; 6-phospho-beta-glucosidase complement(953806..954003) Streptococcus thermophilus LMG 18311 3164299 YP_139535.1 CDS stu1068 NC_006448.1 954247 955383 R hypothetical protein complement(954247..955383) Streptococcus thermophilus LMG 18311 3165182 YP_139536.1 CDS stu1069 NC_006448.1 955462 955689 R truncated; hypothetical protein complement(955462..955689) Streptococcus thermophilus LMG 18311 3164014 YP_139537.1 CDS stu1070 NC_006448.1 955714 955977 R truncated; hypothetical protein complement(955714..955977) Streptococcus thermophilus LMG 18311 3164330 YP_139538.1 CDS stu1071 NC_006448.1 956073 956468 R truncated; hypothetical protein complement(956073..956468) Streptococcus thermophilus LMG 18311 3164771 YP_139539.1 CDS stu1075 NC_006448.1 957092 957667 D hypothetical protein 957092..957667 Streptococcus thermophilus LMG 18311 3165540 YP_139540.1 CDS tnp1193 NC_006448.1 957830 959086 D IS1193 transposase 957830..959086 Streptococcus thermophilus LMG 18311 3164590 YP_139541.1 CDS stu1088 NC_006448.1 959094 959726 R truncated; hypothetical protein complement(959094..959726) Streptococcus thermophilus LMG 18311 3164295 YP_139542.1 CDS stu1087 NC_006448.1 959678 960529 D truncated; hypothetical protein 959678..960529 Streptococcus thermophilus LMG 18311 3164610 YP_139543.1 CDS stu1089 NC_006448.1 960557 961177 R hypothetical protein complement(960557..961177) Streptococcus thermophilus LMG 18311 3164062 YP_139544.1 CDS stu1090 NC_006448.1 961247 961948 R hypothetical protein complement(961247..961948) Streptococcus thermophilus LMG 18311 3164791 YP_139545.1 CDS epsK NC_006448.1 963149 963907 R exopolysaccharide biosynthesis protein, glycosyl transferase complement(963149..963907) Streptococcus thermophilus LMG 18311 3164582 YP_139546.1 CDS eps15 NC_006448.1 963894 965012 R exopolysaccharide biosynthesis protein, glycosyl transferase complement(963894..965012) Streptococcus thermophilus LMG 18311 3163896 YP_139547.1 CDS eps14 NC_006448.1 965123 965746 R hypothetical protein complement(965123..965746) Streptococcus thermophilus LMG 18311 3165488 YP_139548.1 CDS stu1093 NC_006448.1 965241 965897 D hypothetical protein 965241..965897 Streptococcus thermophilus LMG 18311 3164486 YP_139549.1 CDS eps13 NC_006448.1 965887 967062 R exopolysaccharide biosynthesis protein complement(965887..967062) Streptococcus thermophilus LMG 18311 3164491 YP_139550.1 CDS eps12 NC_006448.1 967069 968568 R exopolysaccharide biosynthesis protein, membrane protein complement(967069..968568) Streptococcus thermophilus LMG 18311 3164686 YP_139551.1 CDS eps11 NC_006448.1 968965 969957 R exopolysaccharide biosynthesis protein, glycosyltransferase complement(968965..969957) Streptococcus thermophilus LMG 18311 3165234 YP_139552.1 CDS eps10 NC_006448.1 969982 970722 R exopolysaccharide biosynthesis protein, glycosyltransferase complement(969982..970722) Streptococcus thermophilus LMG 18311 3164811 YP_139553.1 CDS eps9 NC_006448.1 970775 971332 R exopolysaccharide biosynthesis protein complement(970775..971332) Streptococcus thermophilus LMG 18311 3164806 YP_139554.1 CDS eps15 NC_006448.1 971804 972451 R exopolysaccharide biosynthesis protein, glycosyltransferase complement(971804..972451) Streptococcus thermophilus LMG 18311 3164626 YP_139555.1 CDS stu1101 NC_006448.1 972488 972820 R hypothetical protein complement(972488..972820) Streptococcus thermophilus LMG 18311 3164260 YP_139556.1 CDS stu1102 NC_006448.1 973462 974313 R hypothetical protein complement(973462..974313) Streptococcus thermophilus LMG 18311 3164008 YP_139557.1 CDS eps4 NC_006448.1 974456 974935 R exopolysaccharide biosynthesis protein complement(974456..974935) Streptococcus thermophilus LMG 18311 3163902 YP_139558.1 CDS eps3 NC_006448.1 975038 975523 R exopolysaccharide biosynthesis protein, glycosyltransferase complement(975038..975523) Streptococcus thermophilus LMG 18311 3163770 YP_139559.1 CDS eps2 NC_006448.1 975523 975972 R exopolysaccharide biosynthesis protein, glycosyltransferase complement(975523..975972) Streptococcus thermophilus LMG 18311 3164089 YP_139560.1 CDS stu1106 NC_006448.1 975981 976400 R truncated; exopolysaccharide biosynthesis protein, truncated complement(975981..976400) Streptococcus thermophilus LMG 18311 3164780 YP_139561.1 CDS stu1107 NC_006448.1 976420 977004 R truncated; exopolysaccharide biosynthesis protein, truncated complement(976420..977004) Streptococcus thermophilus LMG 18311 3164213 YP_139562.1 CDS epsE NC_006448.1 977206 978573 R exopolysaccharide biosynthesis protein, glycosyl-1-phosphate transferase complement(977206..978573) Streptococcus thermophilus LMG 18311 3164721 YP_139563.1 CDS epsD NC_006448.1 978630 979370 R exopolysaccharide exporter accessory protein complement(978630..979370) Streptococcus thermophilus LMG 18311 3163890 YP_139564.1 CDS epsC NC_006448.1 979380 980072 R exopolysaccharide exporter accessory protein complement(979380..980072) Streptococcus thermophilus LMG 18311 3164972 YP_139565.1 CDS epsB NC_006448.1 980081 980812 R exopolysaccharide biosynthesis protein complement(980081..980812) Streptococcus thermophilus LMG 18311 3164851 YP_139566.1 CDS epsA NC_006448.1 980813 982267 R transcriptional activator-exopolysaccharide biosynthesis complement(980813..982267) Streptococcus thermophilus LMG 18311 3164290 YP_139567.1 CDS deoD NC_006448.1 982613 983323 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(982613..983323) Streptococcus thermophilus LMG 18311 3165036 YP_139568.1 CDS stu1114 NC_006448.1 983757 984020 R truncated; glutamine amidotransferase (GMP synthase), truncated complement(983757..984020) Streptococcus thermophilus LMG 18311 3164574 YP_139569.1 CDS stu1115 NC_006448.1 984017 984217 R truncated; glutamine amidotransferase (GMP synthase), truncated complement(984017..984217) Streptococcus thermophilus LMG 18311 3164742 YP_139570.1 CDS stu1116 NC_006448.1 984715 985116 R truncated; voltage-gated chloride channel family protein, truncated complement(984715..985116) Streptococcus thermophilus LMG 18311 3165583 YP_139571.1 CDS punA NC_006448.1 985475 986284 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(985475..986284) Streptococcus thermophilus LMG 18311 3163983 YP_139572.1 CDS stu1118 NC_006448.1 986305 986724 R truncated; hypothetical protein complement(986305..986724) Streptococcus thermophilus LMG 18311 3165517 YP_139573.1 CDS stu1119 NC_006448.1 986705 986881 R truncated; hypothetical protein complement(986705..986881) Streptococcus thermophilus LMG 18311 3163889 YP_139574.1 CDS deoB NC_006448.1 986850 988061 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(986850..988061) Streptococcus thermophilus LMG 18311 3164438 YP_139575.1 CDS rpiA NC_006448.1 988187 988867 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(988187..988867) Streptococcus thermophilus LMG 18311 3163991 YP_139576.1 CDS stu1122 NC_006448.1 989158 989430 R hypothetical protein complement(989158..989430) Streptococcus thermophilus LMG 18311 3164653 YP_139577.1 CDS stu1123 NC_006448.1 989496 989654 R hypothetical protein complement(989496..989654) Streptococcus thermophilus LMG 18311 3165090 YP_139578.1 CDS tnp1193 NC_006448.1 989766 991022 R IS1193 transposase complement(989766..991022) Streptococcus thermophilus LMG 18311 3165498 YP_139579.1 CDS stu1125 NC_006448.1 991534 991950 R hypothetical protein complement(991534..991950) Streptococcus thermophilus LMG 18311 3164460 YP_139580.1 CDS stu1126 NC_006448.1 992308 992874 R hypothetical protein complement(992308..992874) Streptococcus thermophilus LMG 18311 3164625 YP_139581.1 CDS pepV NC_006448.1 992931 994337 R divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV complement(992931..994337) Streptococcus thermophilus LMG 18311 3165470 YP_139582.1 CDS xylH NC_006448.1 994568 994753 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 994568..994753 Streptococcus thermophilus LMG 18311 3164991 YP_139583.1 CDS stu1129 NC_006448.1 994829 995302 R hypothetical protein complement(994829..995302) Streptococcus thermophilus LMG 18311 3164570 YP_139584.1 CDS stu1130 NC_006448.1 995457 995630 R truncated; hypothetical protein complement(995457..995630) Streptococcus thermophilus LMG 18311 3164866 YP_139585.1 CDS rplT NC_006448.1 996096 996455 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(996096..996455) Streptococcus thermophilus LMG 18311 3164773 YP_139586.1 CDS rpmI NC_006448.1 996512 996712 R 50S ribosomal protein L35 complement(996512..996712) Streptococcus thermophilus LMG 18311 3163883 YP_139587.1 CDS infC NC_006448.1 996751 997281 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(996751..997281) Streptococcus thermophilus LMG 18311 3165432 YP_139588.1 CDS cmk NC_006448.1 997441 998121 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(997441..998121) Streptococcus thermophilus LMG 18311 3164901 YP_139589.1 CDS stu1136 NC_006448.1 998142 998771 R hypothetical protein complement(998142..998771) Streptococcus thermophilus LMG 18311 3164459 YP_139590.1 CDS fer NC_006448.1 998817 999014 D ferredoxin 998817..999014 Streptococcus thermophilus LMG 18311 3163828 YP_139591.1 CDS stu1138 NC_006448.1 998998 999498 R pore-forming peptide complement(998998..999498) Streptococcus thermophilus LMG 18311 3163787 YP_139592.1 CDS pepT NC_006448.1 999555 1000778 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(999555..1000778) Streptococcus thermophilus LMG 18311 3165099 YP_139593.1 CDS sipB NC_006448.1 1000987 1001544 R signal peptidase I complement(1000987..1001544) Streptococcus thermophilus LMG 18311 3164348 YP_139594.1 CDS stu1141 NC_006448.1 1001667 1002926 R hypothetical protein complement(1001667..1002926) Streptococcus thermophilus LMG 18311 3164627 YP_139595.1 CDS stu1142 NC_006448.1 1002886 1004064 R hypothetical protein complement(1002886..1004064) Streptococcus thermophilus LMG 18311 3164772 YP_139596.1 CDS mutT NC_006448.1 1004075 1004557 R 7,8-dihydro-8-oxoguanine-triphosphatase complement(1004075..1004557) Streptococcus thermophilus LMG 18311 3165482 YP_139597.1 CDS ftsX NC_006448.1 1004713 1005678 R cell division ABC transporter permease complement(1004713..1005678) Streptococcus thermophilus LMG 18311 3164199 YP_139598.1 CDS ftsE NC_006448.1 1005635 1006342 R cell division ATP-binding protein complement(1005635..1006342) Streptococcus thermophilus LMG 18311 3164200 YP_139599.1 CDS prfB NC_006448.1 1006415 1007428 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(1006415..1007428) Streptococcus thermophilus LMG 18311 3164203 YP_139600.1 CDS stu1148 NC_006448.1 1007566 1008684 R hypothetical protein complement(1007566..1008684) Streptococcus thermophilus LMG 18311 3164204 YP_139601.1 CDS stu1147 NC_006448.1 1008697 1009641 D hypothetical protein 1008697..1009641 Streptococcus thermophilus LMG 18311 3164201 YP_139602.1 CDS nfrA NC_006448.1 1009665 1010411 R nitro/flavin reductase complement(1009665..1010411) Streptococcus thermophilus LMG 18311 3164205 YP_139603.1 CDS pacL2 NC_006448.1 1010520 1013204 R Ca2+, Mn2+-P-type ATPase complement(1010520..1013204) Streptococcus thermophilus LMG 18311 3164206 YP_139604.1 CDS stu1151 NC_006448.1 1013470 1013856 R hypothetical protein complement(1013470..1013856) Streptococcus thermophilus LMG 18311 3164390 YP_139605.1 CDS stu1152 NC_006448.1 1013948 1014265 R truncated; acetyltransferase complement(1013948..1014265) Streptococcus thermophilus LMG 18311 3164391 YP_139606.1 CDS stu1153 NC_006448.1 1014579 1014716 R truncated; acetyltransferase, truncated complement(1014579..1014716) Streptococcus thermophilus LMG 18311 3164058 YP_139607.1 CDS stu1154 NC_006448.1 1015036 1015845 D hypothetical protein 1015036..1015845 Streptococcus thermophilus LMG 18311 3164358 YP_139608.1 CDS murM NC_006448.1 1015847 1017061 D peptidoglycan branched peptide synthesis protein 1015847..1017061 Streptococcus thermophilus LMG 18311 3164393 YP_139609.1 CDS vicX NC_006448.1 1017533 1018363 R hypothetical protein complement(1017533..1018363) Streptococcus thermophilus LMG 18311 3164395 YP_139610.1 CDS hk05 NC_006448.1 1018351 1019691 R sensor histidine kinase complement(1018351..1019691) Streptococcus thermophilus LMG 18311 3163891 YP_139611.1 CDS rr05 NC_006448.1 1019684 1020391 R response regulator complement(1019684..1020391) Streptococcus thermophilus LMG 18311 3164592 YP_139612.1 CDS stu1161 NC_006448.1 1020918 1021685 D polar amino acid ABC uptake transporter ATP-binding protein 1020918..1021685 Streptococcus thermophilus LMG 18311 3164396 YP_139613.1 CDS stu1162 NC_006448.1 1021697 1022530 D polar amino acid ABC uptake transporter substrate binding protein 1021697..1022530 Streptococcus thermophilus LMG 18311 3164500 YP_139614.1 CDS stu1163 NC_006448.1 1022548 1023246 D polar amino acid ABC uptake transporter membrane-spanning protein 1022548..1023246 Streptococcus thermophilus LMG 18311 3163851 YP_139615.1 CDS stu1164 NC_006448.1 1023258 1023908 D polar amino acid ABC uptake transporter membrane-spanning protein 1023258..1023908 Streptococcus thermophilus LMG 18311 3164020 YP_139616.1 CDS endA NC_006448.1 1023979 1024860 R competence associated membrane nuclease complement(1023979..1024860) Streptococcus thermophilus LMG 18311 3164022 YP_139617.1 CDS epuA NC_006448.1 1024922 1025110 R competence-associated protein complement(1024922..1025110) Streptococcus thermophilus LMG 18311 3164021 YP_139618.1 CDS murA NC_006448.1 1025112 1026398 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1025112..1026398) Streptococcus thermophilus LMG 18311 3164490 YP_139619.1 CDS stu1168 NC_006448.1 1026453 1026689 R hypothetical protein complement(1026453..1026689) Streptococcus thermophilus LMG 18311 3164974 YP_139620.1 CDS galE2 NC_006448.1 1026877 1027890 R UDP-glucose 4-epimerase complement(1026877..1027890) Streptococcus thermophilus LMG 18311 3163774 YP_139621.1 CDS stu1170 NC_006448.1 1027905 1028108 R truncated; hypothetical protein complement(1027905..1028108) Streptococcus thermophilus LMG 18311 3163929 YP_139622.1 CDS stu1171 NC_006448.1 1028124 1028360 R truncated; hypothetical protein complement(1028124..1028360) Streptococcus thermophilus LMG 18311 3164361 YP_139623.2 CDS metK NC_006448.1 1029362 1030555 R methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1029362..1030555) Streptococcus thermophilus LMG 18311 3164346 YP_139624.1 CDS birA NC_006448.1 1030836 1031774 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1030836..1031774 Streptococcus thermophilus LMG 18311 3164485 YP_139625.1 CDS dnaX NC_006448.1 1032173 1033825 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(1032173..1033825) Streptococcus thermophilus LMG 18311 3164471 YP_139626.1 CDS stu1175 NC_006448.1 1033825 1034334 R hypothetical protein complement(1033825..1034334) Streptococcus thermophilus LMG 18311 3164880 YP_139627.1 CDS miaA NC_006448.1 1034370 1035359 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1034370..1035359) Streptococcus thermophilus LMG 18311 3164863 YP_139628.1 CDS stu1176 NC_006448.1 1035345 1035521 D hypothetical protein 1035345..1035521 Streptococcus thermophilus LMG 18311 3165172 YP_139629.1 CDS stu1178 NC_006448.1 1035574 1036113 D hypothetical protein 1035574..1036113 Streptococcus thermophilus LMG 18311 3164708 YP_139630.1 CDS rplS NC_006448.1 1036465 1036812 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1036465..1036812) Streptococcus thermophilus LMG 18311 3165587 YP_139631.1 CDS stu1180 NC_006448.1 1036940 1038166 R chloride channel (CIC) family protein complement(1036940..1038166) Streptococcus thermophilus LMG 18311 3163745 YP_139632.1 CDS aroH NC_006448.1 1038176 1038448 R hypothetical protein complement(1038176..1038448) Streptococcus thermophilus LMG 18311 3164339 YP_139633.1 CDS stu1182 NC_006448.1 1038523 1040058 R chloride channel complement(1038523..1040058) Streptococcus thermophilus LMG 18311 3164115 YP_139634.1 CDS fld NC_006448.1 1040109 1040477 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(1040109..1040477) Streptococcus thermophilus LMG 18311 3163769 YP_139635.1 CDS stu1184 NC_006448.1 1040737 1041009 R hypothetical protein complement(1040737..1041009) Streptococcus thermophilus LMG 18311 3164941 YP_139636.1 CDS stu1185 NC_006448.1 1041021 1041740 R proteinase complement(1041021..1041740) Streptococcus thermophilus LMG 18311 3164944 YP_139637.1 CDS estA NC_006448.1 1041860 1042642 R esterase complement(1041860..1042642) Streptococcus thermophilus LMG 18311 3164947 YP_139638.1 CDS stu1187 NC_006448.1 1042767 1044428 R metallo-beta-lactamase superfamily protein complement(1042767..1044428) Streptococcus thermophilus LMG 18311 3164635 YP_139639.1 CDS stu1188 NC_006448.1 1044609 1045367 R ABC transporter ATP binding protein complement(1044609..1045367) Streptococcus thermophilus LMG 18311 3165110 YP_139640.1 CDS stu1189 NC_006448.1 1045364 1046233 R ABC transporter membrane-spanning protein complement(1045364..1046233) Streptococcus thermophilus LMG 18311 3165538 YP_139641.1 CDS stu1190 NC_006448.1 1046243 1047244 R ABC transporter substrate binding protein complement(1046243..1047244) Streptococcus thermophilus LMG 18311 3164948 YP_139642.1 CDS stu1191 NC_006448.1 1047381 1047602 R hypothetical protein complement(1047381..1047602) Streptococcus thermophilus LMG 18311 3164949 YP_139643.1 CDS stu1192 NC_006448.1 1047804 1048052 R hypothetical protein complement(1047804..1048052) Streptococcus thermophilus LMG 18311 3164569 YP_139644.1 CDS stu1193 NC_006448.1 1048015 1048494 R truncated; surface-associated protein cshA precursor, truncated complement(1048015..1048494) Streptococcus thermophilus LMG 18311 3164546 YP_139645.1 CDS stu1194 NC_006448.1 1048589 1048855 R hypothetical protein complement(1048589..1048855) Streptococcus thermophilus LMG 18311 3164670 YP_139646.1 CDS stu1195 NC_006448.1 1049017 1049256 R hypothetical protein complement(1049017..1049256) Streptococcus thermophilus LMG 18311 3164568 YP_139647.2 CDS pyk NC_006448.1 1050148 1051650 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1050148..1051650) Streptococcus thermophilus LMG 18311 3164178 YP_139648.1 CDS pfkA NC_006448.1 1051720 1052787 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1051720..1052787) Streptococcus thermophilus LMG 18311 3165272 YP_139649.1 CDS dnaE NC_006448.1 1052832 1055942 R Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE complement(1052832..1055942) Streptococcus thermophilus LMG 18311 3165009 YP_139650.1 CDS stu1199 NC_006448.1 1056095 1056880 R hypothetical protein complement(1056095..1056880) Streptococcus thermophilus LMG 18311 3163898 YP_139651.1 CDS leuD NC_006448.1 1056977 1057567 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(1056977..1057567) Streptococcus thermophilus LMG 18311 3163871 YP_139652.1 CDS leuC NC_006448.1 1057577 1058971 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(1057577..1058971) Streptococcus thermophilus LMG 18311 3165608 YP_139653.1 CDS leuB NC_006448.1 1059276 1060322 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(1059276..1060322) Streptococcus thermophilus LMG 18311 3163992 YP_139654.1 CDS leuA NC_006448.1 1060326 1061936 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(1060326..1061936) Streptococcus thermophilus LMG 18311 3165609 YP_139655.1 CDS gpmA NC_006448.1 1062235 1062927 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1062235..1062927) Streptococcus thermophilus LMG 18311 3165581 YP_139656.1 CDS pyrDa NC_006448.1 1063138 1064121 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1063138..1064121 Streptococcus thermophilus LMG 18311 3165549 YP_139657.1 CDS stu1208 NC_006448.1 1064186 1064353 R hypothetical protein complement(1064186..1064353) Streptococcus thermophilus LMG 18311 3165086 YP_139658.1 CDS hstH NC_006448.1 1064445 1064720 R histone-like DNA-binding protein complement(1064445..1064720) Streptococcus thermophilus LMG 18311 3164882 YP_139659.1 CDS stu1210 NC_006448.1 1064857 1065426 R hypothetical protein complement(1064857..1065426) Streptococcus thermophilus LMG 18311 3165360 YP_139660.1 CDS stu1211 NC_006448.1 1065419 1066225 R hypothetical protein complement(1065419..1066225) Streptococcus thermophilus LMG 18311 3163928 YP_139661.1 CDS stu1212 NC_006448.1 1066287 1067123 R hypothetical protein complement(1066287..1067123) Streptococcus thermophilus LMG 18311 3165557 YP_139662.1 CDS recN NC_006448.1 1067194 1068864 R DNA repair and genetic recombination protein complement(1067194..1068864) Streptococcus thermophilus LMG 18311 3163749 YP_139663.1 CDS stu1214 NC_006448.1 1068873 1069319 R transcriptional repressor protein complement(1068873..1069319) Streptococcus thermophilus LMG 18311 3163950 YP_139664.1 CDS stu1215 NC_006448.1 1069267 1070133 R hemolysin complement(1069267..1070133) Streptococcus thermophilus LMG 18311 3163919 YP_139665.1 CDS ispA NC_006448.1 1070126 1070998 R geranyltranstransferase, farnesyl diphosphate synthase complement(1070126..1070998) Streptococcus thermophilus LMG 18311 3164266 YP_139666.1 CDS xseB NC_006448.1 1070998 1071213 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1070998..1071213) Streptococcus thermophilus LMG 18311 3163765 YP_139667.1 CDS xseA NC_006448.1 1071191 1072531 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1071191..1072531) Streptococcus thermophilus LMG 18311 3163938 YP_139668.1 CDS stu1219 NC_006448.1 1072720 1072965 R hypothetical protein complement(1072720..1072965) Streptococcus thermophilus LMG 18311 3164403 YP_139669.1 CDS nth NC_006448.1 1073598 1074257 R endonuclease III, DNA repair complement(1073598..1074257) Streptococcus thermophilus LMG 18311 3164612 YP_139670.1 CDS dnaD NC_006448.1 1074242 1074940 R DNA replication protein dnaD complement(1074242..1074940) Streptococcus thermophilus LMG 18311 3164127 YP_139671.1 CDS metA NC_006448.1 1075012 1075956 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1075012..1075956) Streptococcus thermophilus LMG 18311 3164611 YP_139672.1 CDS apt NC_006448.1 1076127 1076645 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1076127..1076645) Streptococcus thermophilus LMG 18311 3165623 YP_139673.1 CDS recJ NC_006448.1 1076760 1078970 R single strand DNA-specific exonuclease complement(1076760..1078970) Streptococcus thermophilus LMG 18311 3164826 YP_139674.1 CDS stu1225 NC_006448.1 1078983 1079750 R short chain dehydrogenase/reductase family oxidoreductase complement(1078983..1079750) Streptococcus thermophilus LMG 18311 3163976 YP_139675.1 CDS elaC NC_006448.1 1079750 1080679 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1079750..1080679) Streptococcus thermophilus LMG 18311 3164737 YP_139676.1 CDS stu1227 NC_006448.1 1080710 1081351 R hypothetical protein complement(1080710..1081351) Streptococcus thermophilus LMG 18311 3165022 YP_139677.1 CDS hflX NC_006448.1 1081344 1082582 R GTP-binding protein complement(1081344..1082582) Streptococcus thermophilus LMG 18311 3164884 YP_139678.1 CDS rodA NC_006448.1 1082702 1084156 R cell division protein complement(1082702..1084156) Streptococcus thermophilus LMG 18311 3164336 YP_139679.1 CDS stu1230 NC_006448.1 1084306 1084845 R hypothetical protein complement(1084306..1084845) Streptococcus thermophilus LMG 18311 3164210 YP_139680.1 CDS stu1231 NC_006448.1 1084942 1085148 R hypothetical protein complement(1084942..1085148) Streptococcus thermophilus LMG 18311 3163930 YP_139681.1 CDS hisK NC_006448.1 1085245 1085988 R hypothetical protein complement(1085245..1085988) Streptococcus thermophilus LMG 18311 3164149 YP_139682.1 CDS stu1233 NC_006448.1 1085988 1086635 R hypothetical protein complement(1085988..1086635) Streptococcus thermophilus LMG 18311 3165040 YP_139683.1 CDS stu1234 NC_006448.1 1086622 1087395 R N-acetyl-glucosamine catabolism protein complement(1086622..1087395) Streptococcus thermophilus LMG 18311 3165339 YP_139684.1 CDS stu1235 NC_006448.1 1087397 1088140 R acyl-ACP thioesterase complement(1087397..1088140) Streptococcus thermophilus LMG 18311 3164287 YP_139685.1 CDS hemN NC_006448.1 1088141 1089277 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1088141..1089277) Streptococcus thermophilus LMG 18311 3165324 YP_139686.1 CDS stu1237 NC_006448.1 1089546 1089695 R hypothetical protein complement(1089546..1089695) Streptococcus thermophilus LMG 18311 3165552 YP_139687.1 CDS stu1238 NC_006448.1 1089875 1090129 D hypothetical protein 1089875..1090129 Streptococcus thermophilus LMG 18311 3165417 YP_139688.1 CDS stu1239 NC_006448.1 1090244 1090573 R hypothetical protein complement(1090244..1090573) Streptococcus thermophilus LMG 18311 3165411 YP_139689.1 CDS stu1240 NC_006448.1 1090752 1091012 R hypothetical protein complement(1090752..1091012) Streptococcus thermophilus LMG 18311 3165385 YP_139690.1 CDS stu1241 NC_006448.1 1091033 1091245 R hypothetical protein complement(1091033..1091245) Streptococcus thermophilus LMG 18311 3165589 YP_139691.1 CDS rmlB NC_006448.1 1091408 1092454 R dTDP-glucose-4,6-dehydratase complement(1091408..1092454) Streptococcus thermophilus LMG 18311 3163751 YP_139692.1 CDS rmlC NC_006448.1 1092884 1093477 R dTDP-4-keto-L-rhamnose reductase complement(1092884..1093477) Streptococcus thermophilus LMG 18311 3165338 YP_139693.1 CDS rmlA NC_006448.1 1093477 1094346 R glucose-1-phosphate thymidyl transferase complement(1093477..1094346) Streptococcus thermophilus LMG 18311 3165501 YP_139694.1 CDS stu1245 NC_006448.1 1094578 1095681 R oxidoreductase, DadA family protein/D-amino acid oxidase complement(1094578..1095681) Streptococcus thermophilus LMG 18311 3165437 YP_139695.1 CDS stu1246 NC_006448.1 1095736 1096056 R truncated; hypothetical protein complement(1095736..1096056) Streptococcus thermophilus LMG 18311 3165465 YP_139696.1 CDS stu1247 NC_006448.1 1095827 1096369 R truncated; hypothetical protein complement(1095827..1096369) Streptococcus thermophilus LMG 18311 3165440 YP_139697.1 CDS stu1248 NC_006448.1 1096578 1097366 R hypothetical protein complement(1096578..1097366) Streptococcus thermophilus LMG 18311 3165160 YP_139698.1 CDS stu1249 NC_006448.1 1097356 1098042 R hypothetical protein complement(1097356..1098042) Streptococcus thermophilus LMG 18311 3165344 YP_139699.1 CDS stu1250 NC_006448.1 1098140 1098580 R hypothetical protein complement(1098140..1098580) Streptococcus thermophilus LMG 18311 3165261 YP_139700.1 CDS glmM NC_006448.1 1098583 1099935 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1098583..1099935) Streptococcus thermophilus LMG 18311 3165474 YP_139701.1 CDS stu1252 NC_006448.1 1100159 1101124 R hypothetical protein complement(1100159..1101124) Streptococcus thermophilus LMG 18311 3164281 YP_139702.1 CDS stu1253 NC_006448.1 1101121 1101978 R hypothetical protein complement(1101121..1101978) Streptococcus thermophilus LMG 18311 3165409 YP_139703.1 CDS stu1254 NC_006448.1 1102074 1103417 D Mur ligase family protein 1102074..1103417 Streptococcus thermophilus LMG 18311 3165407 YP_139704.1 CDS cobQ NC_006448.1 1103417 1104205 D cobyric acid synthase 1103417..1104205 Streptococcus thermophilus LMG 18311 3165060 YP_139705.1 CDS stu1256 NC_006448.1 1104256 1106811 R hypothetical protein complement(1104256..1106811) Streptococcus thermophilus LMG 18311 3165354 YP_139706.1 CDS stu1257 NC_006448.1 1106808 1107527 R hypothetical protein complement(1106808..1107527) Streptococcus thermophilus LMG 18311 3165460 YP_139707.1 CDS stu1259 NC_006448.1 1108053 1109972 R ABC transporter ATP-binding protein complement(1108053..1109972) Streptococcus thermophilus LMG 18311 3165353 YP_139708.1 CDS udk NC_006448.1 1110009 1110644 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(1110009..1110644) Streptococcus thermophilus LMG 18311 3165480 YP_139709.1 CDS deaD NC_006448.1 1110742 1111824 D ATP-dependent RNA helicase 1110742..1111824 Streptococcus thermophilus LMG 18311 3163825 YP_139710.1 CDS gapN NC_006448.1 1112113 1113546 R NADP-dependent glyceraldehyde-3-phosphate dehydrogenase complement(1112113..1113546) Streptococcus thermophilus LMG 18311 3164276 YP_139711.1 CDS ptsI NC_006448.1 1113764 1115497 R phosphoenolpyruvate:sugar phosphotransferase system enzyme I complement(1113764..1115497) Streptococcus thermophilus LMG 18311 3165255 YP_139712.1 CDS ptsH NC_006448.1 1115502 1115765 R phosphocarrier protein HPr complement(1115502..1115765) Streptococcus thermophilus LMG 18311 3165442 YP_139713.1 CDS icd NC_006448.1 1116027 1117202 R isocitrate dehydrogenase complement(1116027..1117202) Streptococcus thermophilus LMG 18311 3165469 YP_139714.1 CDS gltA NC_006448.1 1117217 1118341 R catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase complement(1117217..1118341) Streptococcus thermophilus LMG 18311 3165431 YP_139715.1 CDS citB NC_006448.1 1118343 1121006 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1118343..1121006) Streptococcus thermophilus LMG 18311 3165389 YP_139716.1 CDS nrdH NC_006448.1 1121337 1121561 D glutaredoxin 1121337..1121561 Streptococcus thermophilus LMG 18311 3165309 YP_139717.1 CDS nrdE NC_006448.1 1121648 1123807 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1121648..1123807 Streptococcus thermophilus LMG 18311 3165252 YP_139718.1 CDS nrdF NC_006448.1 1123966 1124928 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1123966..1124928 Streptococcus thermophilus LMG 18311 3165510 YP_139719.1 CDS stu1272 NC_006448.1 1125244 1125450 D truncated; truncated IS1193 transposase 1125244..1125450 Streptococcus thermophilus LMG 18311 3165364 YP_139720.1 CDS stu1273 NC_006448.1 1125594 1126019 D truncated; hypothetical protein 1125594..1126019 Streptococcus thermophilus LMG 18311 3165551 YP_139721.1 CDS stu1274 NC_006448.1 1126073 1126459 D truncated; hypothetical protein 1126073..1126459 Streptococcus thermophilus LMG 18311 3165346 YP_139722.1 CDS stu1275 NC_006448.1 1126724 1127692 R hypothetical protein complement(1126724..1127692) Streptococcus thermophilus LMG 18311 3165421 YP_139723.1 CDS stu1276 NC_006448.1 1127889 1128218 R hypothetical protein complement(1127889..1128218) Streptococcus thermophilus LMG 18311 3165302 YP_139724.1 CDS stu1277 NC_006448.1 1128243 1128620 R truncated; sortase, truncated complement(1128243..1128620) Streptococcus thermophilus LMG 18311 3165297 YP_139725.1 CDS stu1278 NC_006448.1 1128633 1129004 R truncated; sortase, truncated complement(1128633..1129004) Streptococcus thermophilus LMG 18311 3165066 YP_139726.1 CDS gyrA NC_006448.1 1129037 1131472 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1129037..1131472) Streptococcus thermophilus LMG 18311 3165299 YP_139727.1 CDS ldh NC_006448.1 1131691 1132677 D Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1131691..1132677 Streptococcus thermophilus LMG 18311 3165511 YP_139728.1 CDS nox NC_006448.1 1132770 1134155 R NADH oxidase (H2O-forming) complement(1132770..1134155) Streptococcus thermophilus LMG 18311 3165373 YP_139729.1 CDS stu1282 NC_006448.1 1134459 1135997 R ABC transporter ATP-binding protein complement(1134459..1135997) Streptococcus thermophilus LMG 18311 3165289 YP_139730.1 CDS stu1283 NC_006448.1 1136068 1136559 R hypothetical protein complement(1136068..1136559) Streptococcus thermophilus LMG 18311 3165321 YP_139731.1 CDS pdxK NC_006448.1 1136696 1137517 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1136696..1137517) Streptococcus thermophilus LMG 18311 3165384 YP_139732.1 CDS stu1285 NC_006448.1 1137518 1138027 R hypothetical protein complement(1137518..1138027) Streptococcus thermophilus LMG 18311 3165582 YP_139733.1 CDS stu1286 NC_006448.1 1138165 1138695 R hypothetical protein complement(1138165..1138695) Streptococcus thermophilus LMG 18311 3165356 YP_139734.1 CDS stu1287 NC_006448.1 1138853 1139191 D truncated; transcriptional regulator, truncated 1138853..1139191 Streptococcus thermophilus LMG 18311 3165284 YP_139735.1 CDS stu1288 NC_006448.1 1139318 1140118 D truncated; transcriptional regulator, truncated 1139318..1140118 Streptococcus thermophilus LMG 18311 3164698 YP_139736.1 CDS stu1289 NC_006448.1 1140162 1140500 R hypothetical protein complement(1140162..1140500) Streptococcus thermophilus LMG 18311 3164175 YP_139737.1 CDS stu1290 NC_006448.1 1140591 1140896 R hypothetical protein complement(1140591..1140896) Streptococcus thermophilus LMG 18311 3165307 YP_139738.1 CDS pheT NC_006448.1 1141232 1143682 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1141232..1143682) Streptococcus thermophilus LMG 18311 3165416 YP_139739.1 CDS stu1293 NC_006448.1 1143941 1144459 R transcriptional regulator complement(1143941..1144459) Streptococcus thermophilus LMG 18311 3165316 YP_139740.2 CDS pheS NC_006448.1 1144476 1145519 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1144476..1145519) Streptococcus thermophilus LMG 18311 3164424 YP_139741.1 CDS smc NC_006448.1 1146139 1149672 R chromosome segregation SMC protein complement(1146139..1149672) Streptococcus thermophilus LMG 18311 3165314 YP_139742.1 CDS rnc NC_006448.1 1149675 1150388 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(1149675..1150388) Streptococcus thermophilus LMG 18311 3165326 YP_139743.1 CDS dapA NC_006448.1 1150519 1151490 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(1150519..1151490) Streptococcus thermophilus LMG 18311 3165374 YP_139744.1 CDS asd NC_006448.1 1151792 1152868 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1151792..1152868) Streptococcus thermophilus LMG 18311 3165288 YP_139745.1 CDS alkD NC_006448.1 1153158 1153637 R DNA alkylation repair protein complement(1153158..1153637) Streptococcus thermophilus LMG 18311 3165461 YP_139746.1 CDS stu1301 NC_006448.1 1153999 1154580 R phosphinothricin acetyltransferase complement(1153999..1154580) Streptococcus thermophilus LMG 18311 3165503 YP_139747.1 CDS stu1302 NC_006448.1 1154804 1155010 D truncated; truncated IS1193 transposase 1154804..1155010 Streptococcus thermophilus LMG 18311 3165375 YP_139748.1 CDS stu1303 NC_006448.1 1155128 1155364 D truncated; truncated IS1193 transposase 1155128..1155364 Streptococcus thermophilus LMG 18311 3165542 YP_139749.1 CDS stu1304 NC_006448.1 1155357 1155524 D truncated; truncated IS1193 transposase 1155357..1155524 Streptococcus thermophilus LMG 18311 3165056 YP_139750.1 CDS cls NC_006448.1 1155563 1157014 R cardiolipin synthetase complement(1155563..1157014) Streptococcus thermophilus LMG 18311 3165359 YP_139751.1 CDS uvrC NC_006448.1 1157202 1158989 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1157202..1158989) Streptococcus thermophilus LMG 18311 3165332 YP_139752.1 CDS stu1307 NC_006448.1 1159049 1159744 R HAD superfamily hydrolase complement(1159049..1159744) Streptococcus thermophilus LMG 18311 3163758 YP_139753.1 CDS bioY2 NC_006448.1 1160071 1160505 D biotin synthase 1160071..1160505 Streptococcus thermophilus LMG 18311 3165371 YP_139754.1 CDS proWX NC_006448.1 1160740 1161429 R choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein complement(1160740..1161429) Streptococcus thermophilus LMG 18311 3165573 YP_139755.1 CDS proV NC_006448.1 1161371 1162126 R choline/proline/glycine betaine ABC uptake transporter ATP-binding protein complement(1161371..1162126) Streptococcus thermophilus LMG 18311 3165518 YP_139756.1 CDS proWY NC_006448.1 1162138 1163055 R choline/proline/glycine betaine ABC uptake transporter substrate binding protein complement(1162138..1163055) Streptococcus thermophilus LMG 18311 3165313 YP_139757.1 CDS proWZ NC_006448.1 1163052 1163711 R choline/proline/glycine betaine ABC uptake transporter membrane-spanning protein complement(1163052..1163711) Streptococcus thermophilus LMG 18311 3164264 YP_139758.1 CDS hutH NC_006448.1 1163768 1165264 R histidine ammonia-lyase complement(1163768..1165264) Streptococcus thermophilus LMG 18311 3165430 YP_139759.1 CDS stu1314 NC_006448.1 1165287 1166390 R hypothetical protein complement(1165287..1166390) Streptococcus thermophilus LMG 18311 3164263 YP_139760.1 CDS hutU NC_006448.1 1166407 1168041 R catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase complement(1166407..1168041) Streptococcus thermophilus LMG 18311 3165487 YP_139761.1 CDS sdaB NC_006448.1 1168480 1169193 D L-serine dehydratase subunit beta 1168480..1169193 Streptococcus thermophilus LMG 18311 3165526 YP_139762.1 CDS sdaA NC_006448.1 1169206 1170075 D L-serine dehydratase subunit alpha 1169206..1170075 Streptococcus thermophilus LMG 18311 3164026 YP_139763.1 CDS stu1318 NC_006448.1 1170798 1171367 R hypothetical protein complement(1170798..1171367) Streptococcus thermophilus LMG 18311 3165287 YP_139764.1 CDS stu1319 NC_006448.1 1171503 1172294 R hypothetical protein complement(1171503..1172294) Streptococcus thermophilus LMG 18311 3164262 YP_139765.1 CDS stu1320 NC_006448.1 1172291 1172572 R truncated; hypothetical protein complement(1172291..1172572) Streptococcus thermophilus LMG 18311 3165327 YP_139766.1 CDS stu1321 NC_006448.1 1172542 1173114 R truncated; hypothetical protein complement(1172542..1173114) Streptococcus thermophilus LMG 18311 3165453 YP_139767.1 CDS stu1322 NC_006448.1 1173300 1173518 R truncated; ABC transporter ATP binding protein, truncated complement(1173300..1173518) Streptococcus thermophilus LMG 18311 3165310 YP_139768.1 CDS stu1323 NC_006448.1 1173496 1173663 R truncated; ABC transporter ATP binding protein, truncated complement(1173496..1173663) Streptococcus thermophilus LMG 18311 3165280 YP_139769.1 CDS stu1324 NC_006448.1 1173679 1173933 R truncated; ABC transporter ATP binding protein, truncated complement(1173679..1173933) Streptococcus thermophilus LMG 18311 3165471 YP_139770.1 CDS rr06 NC_006448.1 1174475 1175077 R response regulator complement(1174475..1175077) Streptococcus thermophilus LMG 18311 3164256 YP_139771.1 CDS hk06 NC_006448.1 1175074 1176174 R sensor histidine kinase complement(1175074..1176174) Streptococcus thermophilus LMG 18311 3165450 YP_139772.1 CDS stu1327 NC_006448.1 1176161 1176898 R ABC transporter membrane-spanning protein complement(1176161..1176898) Streptococcus thermophilus LMG 18311 3165336 YP_139773.1 CDS stu1328 NC_006448.1 1176895 1177776 R ABC transporter ATP binding protein complement(1176895..1177776) Streptococcus thermophilus LMG 18311 3165516 YP_139774.1 CDS stu1329 NC_006448.1 1177959 1178168 R hypothetical protein complement(1177959..1178168) Streptococcus thermophilus LMG 18311 3165475 YP_139775.1 CDS stu1330 NC_006448.1 1178320 1179258 R bile acid:Na+ symporter (BASS) family protein complement(1178320..1179258) Streptococcus thermophilus LMG 18311 3165386 YP_139776.1 CDS stu1331 NC_006448.1 1179404 1179853 R cytidine/deoxycytidylate deaminase family protein complement(1179404..1179853) Streptococcus thermophilus LMG 18311 3165515 YP_139777.1 CDS stu1332 NC_006448.1 1180021 1180242 R hypothetical protein complement(1180021..1180242) Streptococcus thermophilus LMG 18311 3165293 YP_139778.1 CDS stu1333 NC_006448.1 1180327 1182327 R peptide-4 ABC transporter substrate binding/membrane-spanning protein complement(1180327..1182327) Streptococcus thermophilus LMG 18311 3164248 YP_139779.1 CDS stu1334 NC_006448.1 1182329 1183087 R peptide-4 ABC transporter ATP binding protein complement(1182329..1183087) Streptococcus thermophilus LMG 18311 3164416 YP_139780.1 CDS hk07 NC_006448.1 1183232 1184206 R sensor histidine kinase complement(1183232..1184206) Streptococcus thermophilus LMG 18311 3164775 YP_139781.1 CDS rr07 NC_006448.1 1184196 1184876 R response regulator complement(1184196..1184876) Streptococcus thermophilus LMG 18311 3165400 YP_139782.1 CDS stu1337 NC_006448.1 1185428 1185565 D truncated; xanthine phosphoribosyltransferase, truncated 1185428..1185565 Streptococcus thermophilus LMG 18311 3163822 YP_139783.1 CDS stu1338 NC_006448.1 1185543 1185908 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1185543..1185908 Streptococcus thermophilus LMG 18311 3165387 YP_139784.1 CDS stu1339 NC_006448.1 1185997 1186467 D truncated; hypothetical protein 1185997..1186467 Streptococcus thermophilus LMG 18311 3165322 YP_139785.1 CDS stu1340 NC_006448.1 1186473 1187177 D truncated; hypothetical protein 1186473..1187177 Streptococcus thermophilus LMG 18311 3165452 YP_139786.1 CDS norM NC_006448.1 1187305 1188654 D MATE family drug:Na+ antiporter 1187305..1188654 Streptococcus thermophilus LMG 18311 3163913 YP_139787.1 CDS msrA1 NC_006448.1 1189021 1190043 R this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein complement(1189021..1190043) Streptococcus thermophilus LMG 18311 3164136 YP_139788.1 CDS tnpSth1 NC_006448.1 1190123 1190992 R IS3 familytransposase orf2 complement(1190123..1190992) Streptococcus thermophilus LMG 18311 3165484 YP_139789.1 CDS tnpSth1 NC_006448.1 1191007 1191747 R IS3 familytransposase orf1 complement(1191007..1191747) Streptococcus thermophilus LMG 18311 3165347 YP_139790.1 CDS brnQ NC_006448.1 1191786 1193114 R branched chain amino acid:Na+ symporter complement(1191786..1193114) Streptococcus thermophilus LMG 18311 3164758 YP_139791.1 CDS stu1358 NC_006448.1 1193328 1193714 R truncated; mannose-6-phosphate isomerase complement(1193328..1193714) Streptococcus thermophilus LMG 18311 3165361 YP_139792.1 CDS stu1359 NC_006448.1 1193689 1194027 R truncated; mannose-6-phosphate isomerase complement(1193689..1194027) Streptococcus thermophilus LMG 18311 3165378 YP_139793.1 CDS stu1360 NC_006448.1 1194172 1194366 D hypothetical protein 1194172..1194366 Streptococcus thermophilus LMG 18311 3164983 YP_139794.1 CDS stu1361 NC_006448.1 1195236 1196621 R amino acid transporter (AAT) family protein complement(1195236..1196621) Streptococcus thermophilus LMG 18311 3165277 YP_139795.1 CDS stu1363 NC_006448.1 1197047 1197649 R hypothetical protein complement(1197047..1197649) Streptococcus thermophilus LMG 18311 3165294 YP_139796.1 CDS stu1364 NC_006448.1 1197829 1197954 R truncated; hypothetical protein complement(1197829..1197954) Streptococcus thermophilus LMG 18311 3165462 YP_139797.1 CDS stu1365 NC_006448.1 1198102 1198608 R truncated; hypothetical protein complement(1198102..1198608) Streptococcus thermophilus LMG 18311 3165337 YP_139798.1 CDS stu1366 NC_006448.1 1198776 1199225 R Rrf2 family protein complement(1198776..1199225) Streptococcus thermophilus LMG 18311 3165413 YP_139799.1 CDS stu1367 NC_006448.1 1199407 1200270 R hypothetical protein complement(1199407..1200270) Streptococcus thermophilus LMG 18311 3165481 YP_139800.1 CDS celB NC_006448.1 1200257 1201549 R cellobiose PTS system component IIC complement(1200257..1201549) Streptococcus thermophilus LMG 18311 3165383 YP_139801.1 CDS stu1369 NC_006448.1 1201738 1202391 R NAD(P)H nitroreductase complement(1201738..1202391) Streptococcus thermophilus LMG 18311 3165271 YP_139802.1 CDS stu1370 NC_006448.1 1202463 1203002 R hypothetical protein complement(1202463..1203002) Streptococcus thermophilus LMG 18311 3165590 YP_139803.1 CDS stu1371 NC_006448.1 1203210 1204112 R aldo/keto reductase complement(1203210..1204112) Streptococcus thermophilus LMG 18311 3165348 YP_139804.1 CDS stu1373 NC_006448.1 1204185 1204742 R truncated; UDP-glucose 4-epimerase, truncated complement(1204185..1204742) Streptococcus thermophilus LMG 18311 3164238 YP_139805.1 CDS sthII NC_006448.1 1205092 1209504 R type II restriction-modification system restriction subunit complement(1205092..1209504) Streptococcus thermophilus LMG 18311 3165490 YP_139806.1 CDS llaBIIM NC_006448.1 1209511 1210185 R type II restriction-modification system modification subunit complement(1209511..1210185) Streptococcus thermophilus LMG 18311 3164567 YP_139807.1 CDS stu1377 NC_006448.1 1210446 1211930 D hypothetical protein 1210446..1211930 Streptococcus thermophilus LMG 18311 3165081 YP_139808.1 CDS stu1378 NC_006448.1 1212150 1212494 R hypothetical protein complement(1212150..1212494) Streptococcus thermophilus LMG 18311 3165365 YP_139809.1 CDS stu1379 NC_006448.1 1212754 1213017 D hypothetical protein 1212754..1213017 Streptococcus thermophilus LMG 18311 3165395 YP_139810.1 CDS stu1380 NC_006448.1 1213203 1213478 R truncated; response regulator, truncated complement(1213203..1213478) Streptococcus thermophilus LMG 18311 3165392 YP_139811.1 CDS stu1381 NC_006448.1 1213524 1213886 R truncated; response regulator, truncated complement(1213524..1213886) Streptococcus thermophilus LMG 18311 3165535 YP_139812.1 CDS stu1382 NC_006448.1 1213966 1214421 R cell wall surface anchor family protein complement(1213966..1214421) Streptococcus thermophilus LMG 18311 3165533 YP_139813.1 CDS stu1383 NC_006448.1 1214459 1214677 D hypothetical protein 1214459..1214677 Streptococcus thermophilus LMG 18311 3165342 YP_139814.1 CDS stu1384 NC_006448.1 1214723 1215082 R hypothetical protein complement(1214723..1215082) Streptococcus thermophilus LMG 18311 3165493 YP_139815.1 CDS umuC1 NC_006448.1 1215079 1216494 R SOS responce UmuC protein complement(1215079..1216494) Streptococcus thermophilus LMG 18311 3164915 YP_139816.1 CDS stu1386 NC_006448.1 1216667 1217704 R hypothetical protein complement(1216667..1217704) Streptococcus thermophilus LMG 18311 3165525 YP_139817.1 CDS stu1387 NC_006448.1 1217942 1218229 D hypothetical protein 1217942..1218229 Streptococcus thermophilus LMG 18311 3165415 YP_139818.1 CDS stu1388 NC_006448.1 1218478 1218726 D hypothetical protein 1218478..1218726 Streptococcus thermophilus LMG 18311 3165341 YP_139819.1 CDS stu1389 NC_006448.1 1218937 1219554 D resistance to homoserine/threonine (RhtB) family protein 1218937..1219554 Streptococcus thermophilus LMG 18311 3165278 YP_139820.1 CDS stu1390 NC_006448.1 1219840 1219932 D truncated; truncated IS1193 transposase 1219840..1219932 Streptococcus thermophilus LMG 18311 3164233 YP_139821.1 CDS stu1391 NC_006448.1 1219895 1220254 R hypothetical protein complement(1219895..1220254) Streptococcus thermophilus LMG 18311 3165495 YP_139822.1 CDS stu1392 NC_006448.1 1220812 1222905 R glycosyl transferase complement(1220812..1222905) Streptococcus thermophilus LMG 18311 3165317 YP_139823.1 CDS stu1393 NC_006448.1 1223484 1223819 D hypothetical protein 1223484..1223819 Streptococcus thermophilus LMG 18311 3165300 YP_139824.1 CDS sbcC NC_006448.1 1224240 1227419 R ATP-dependent dsDNA exonuclease complement(1224240..1227419) Streptococcus thermophilus LMG 18311 3165463 YP_139825.1 CDS sbcD NC_006448.1 1227416 1228642 R ATP-dependent dsDNA exonuclease complement(1227416..1228642) Streptococcus thermophilus LMG 18311 3165276 YP_139826.1 CDS lacZ NC_006448.1 1229478 1232558 R beta-galactosidase complement(1229478..1232558) Streptococcus thermophilus LMG 18311 3164581 YP_139827.1 CDS lacS NC_006448.1 1232562 1234466 R lactose permease complement(1232562..1234466) Streptococcus thermophilus LMG 18311 3165412 YP_139828.1 CDS galM NC_006448.1 1234569 1235615 R aldose 1-epimerase complement(1234569..1235615) Streptococcus thermophilus LMG 18311 3165335 YP_139829.1 CDS galE1 NC_006448.1 1235685 1236686 R UDP-glucose 4-epimerase complement(1235685..1236686) Streptococcus thermophilus LMG 18311 3165282 YP_139830.1 CDS galT NC_006448.1 1236716 1238224 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1236716..1238224) Streptococcus thermophilus LMG 18311 3164795 YP_139831.1 CDS galK NC_006448.1 1238217 1239383 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(1238217..1239383) Streptococcus thermophilus LMG 18311 3165328 YP_139832.1 CDS galR NC_006448.1 1239526 1240521 D galactose operon repressor 1239526..1240521 Streptococcus thermophilus LMG 18311 3164454 YP_139833.1 CDS stu1405 NC_006448.1 1241316 1241504 R truncated; hypothetical protein complement(1241316..1241504) Streptococcus thermophilus LMG 18311 3164218 YP_139834.1 CDS stu1406 NC_006448.1 1241677 1242768 R truncated; zinc metalloprotease ZmpB, truncated complement(1241677..1242768) Streptococcus thermophilus LMG 18311 3164230 YP_139835.1 CDS stu1407 NC_006448.1 1242731 1243171 R truncated; zinc metalloprotease ZmpB, truncated complement(1242731..1243171) Streptococcus thermophilus LMG 18311 3165304 YP_139836.1 CDS stu1408 NC_006448.1 1243202 1243300 R truncated; zinc metalloprotease ZmpB, truncated complement(1243202..1243300) Streptococcus thermophilus LMG 18311 3164229 YP_139837.1 CDS stu1409 NC_006448.1 1243667 1243927 D truncated; ABC transporter ATP binding protein, truncated 1243667..1243927 Streptococcus thermophilus LMG 18311 3165402 YP_139838.1 CDS stu1410 NC_006448.1 1243982 1244083 R truncated; ABC transporter ATP binding protein complement(1243982..1244083) Streptococcus thermophilus LMG 18311 3164668 YP_139839.1 CDS stu1411 NC_006448.1 1244114 1244680 R truncated; ABC transporter, truncated complement(1244114..1244680) Streptococcus thermophilus LMG 18311 3165367 YP_139840.1 CDS stu1412 NC_006448.1 1244566 1244838 R truncated; ABC transporter, truncated complement(1244566..1244838) Streptococcus thermophilus LMG 18311 3165372 YP_139841.1 CDS stu1413 NC_006448.1 1245523 1247787 D Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1245523..1247787 Streptococcus thermophilus LMG 18311 3165343 YP_139842.1 CDS stu1414 NC_006448.1 1247844 1248509 D truncated; truncated IS1193 transposase 1247844..1248509 Streptococcus thermophilus LMG 18311 3165443 YP_139843.1 CDS stu1415 NC_006448.1 1248807 1248977 D truncated; truncated IS1193 transposase 1248807..1248977 Streptococcus thermophilus LMG 18311 3165467 YP_139844.1 CDS ftsK NC_006448.1 1249096 1251525 R cell division protein complement(1249096..1251525) Streptococcus thermophilus LMG 18311 3165312 YP_139845.1 CDS trxB2 NC_006448.1 1251678 1252676 R thioredoxin reductase complement(1251678..1252676) Streptococcus thermophilus LMG 18311 3165597 YP_139846.1 CDS trmD NC_006448.1 1252678 1253397 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1252678..1253397) Streptococcus thermophilus LMG 18311 3165444 YP_139847.1 CDS rimM NC_006448.1 1253387 1253905 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1253387..1253905) Streptococcus thermophilus LMG 18311 3165286 YP_139848.1 CDS rr08 NC_006448.1 1254576 1255220 R response regulator complement(1254576..1255220) Streptococcus thermophilus LMG 18311 3165543 YP_139849.1 CDS hk08 NC_006448.1 1255210 1256220 R sensor histidine kinase complement(1255210..1256220) Streptococcus thermophilus LMG 18311 3165377 YP_139850.1 CDS stu1422 NC_006448.1 1256217 1256915 R hypothetical protein complement(1256217..1256915) Streptococcus thermophilus LMG 18311 3165363 YP_139851.1 CDS stu1423 NC_006448.1 1257181 1257336 R truncated; potassium channel, truncated complement(1257181..1257336) Streptococcus thermophilus LMG 18311 3163953 YP_139852.1 CDS stu1424 NC_006448.1 1257568 1257720 R truncated; potassium channel, truncated complement(1257568..1257720) Streptococcus thermophilus LMG 18311 3165563 YP_139853.1 CDS pknB NC_006448.1 1257973 1259844 R protein kinase complement(1257973..1259844) Streptococcus thermophilus LMG 18311 3165410 YP_139854.1 CDS pppL NC_006448.1 1259844 1260662 R phosphoprotein phosphatase complement(1259844..1260662) Streptococcus thermophilus LMG 18311 3165270 YP_139855.1 CDS sunL NC_006448.1 1260625 1261956 R RNA-binding protein complement(1260625..1261956) Streptococcus thermophilus LMG 18311 3165445 YP_139856.1 CDS fmt NC_006448.1 1261937 1262872 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1261937..1262872) Streptococcus thermophilus LMG 18311 3164338 YP_139857.1 CDS priA NC_006448.1 1262890 1265286 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1262890..1265286) Streptococcus thermophilus LMG 18311 3165404 YP_139858.1 CDS rpoZ NC_006448.1 1265428 1265742 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1265428..1265742) Streptococcus thermophilus LMG 18311 3165604 YP_139859.1 CDS gmk NC_006448.1 1265764 1266393 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1265764..1266393) Streptococcus thermophilus LMG 18311 3165408 YP_139860.1 CDS ftsY NC_006448.1 1266626 1268017 R signal recognition particle receptor (docking protein) complement(1266626..1268017) Streptococcus thermophilus LMG 18311 3164351 YP_139861.1 CDS stu1433 NC_006448.1 1268031 1268846 R hypothetical protein complement(1268031..1268846) Streptococcus thermophilus LMG 18311 3165274 YP_139862.1 CDS stu1434 NC_006448.1 1268839 1269633 R hypothetical protein complement(1268839..1269633) Streptococcus thermophilus LMG 18311 3164224 YP_139863.1 CDS stu1435 NC_006448.1 1269817 1270194 D GntR family transcriptional regulator 1269817..1270194 Streptococcus thermophilus LMG 18311 3165447 YP_139864.1 CDS stu1436 NC_006448.1 1270199 1270897 D ABC transporter ATP binding protein 1270199..1270897 Streptococcus thermophilus LMG 18311 3165436 YP_139865.1 CDS stu1437 NC_006448.1 1270903 1271694 D ABC transporter membrane-spanning protein 1270903..1271694 Streptococcus thermophilus LMG 18311 3164757 YP_139866.1 CDS amiF1 NC_006448.1 1271744 1272688 R oligopeptide ABC uptake transporter ATP-binding protein complement(1271744..1272688) Streptococcus thermophilus LMG 18311 3165362 YP_139867.1 CDS amiE NC_006448.1 1272666 1273751 R oligopeptide ABC uptake transporter ATP-binding protein complement(1272666..1273751) Streptococcus thermophilus LMG 18311 3165303 YP_139868.1 CDS amiD NC_006448.1 1273761 1274687 R oligopeptide ABC uptake transporter membrane-binding protein complement(1273761..1274687) Streptococcus thermophilus LMG 18311 3165283 YP_139869.1 CDS amiC NC_006448.1 1274687 1276180 R oligopeptide ABC uptake transporter membrane-binding protein complement(1274687..1276180) Streptococcus thermophilus LMG 18311 3165603 YP_139870.1 CDS stu1442 NC_006448.1 1276242 1278209 R truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated complement(1276242..1278209) Streptococcus thermophilus LMG 18311 3164387 YP_139871.1 CDS tnp1193 NC_006448.1 1278565 1279821 D IS1193 transposase 1278565..1279821 Streptococcus thermophilus LMG 18311 3164143 YP_139872.1 CDS amiA3 NC_006448.1 1279859 1281832 R oligopeptide ABC uptake transporter substrate-binding protein complement(1279859..1281832) Streptococcus thermophilus LMG 18311 3164729 YP_139873.1 CDS stu1446 NC_006448.1 1282036 1282143 R truncated; hypothetical protein complement(1282036..1282143) Streptococcus thermophilus LMG 18311 3164384 YP_139874.1 CDS stu1447 NC_006448.1 1282217 1282711 R truncated; oligopeptide ABC uptake transporter ATP-binding protein, truncated complement(1282217..1282711) Streptococcus thermophilus LMG 18311 3164551 YP_139875.1 CDS stu1449 NC_006448.1 1282818 1283018 R hypothetical protein complement(1282818..1283018) Streptococcus thermophilus LMG 18311 3165399 YP_139876.1 CDS oxlT NC_006448.1 1283326 1284531 D oxalate:formate antiporter 1283326..1284531 Streptococcus thermophilus LMG 18311 3165477 YP_139877.1 CDS stu1451 NC_006448.1 1284577 1285215 R truncated; hypothetical protein complement(1284577..1285215) Streptococcus thermophilus LMG 18311 3164375 YP_139878.1 CDS stu1452 NC_006448.1 1285222 1285416 R truncated; hypothetical protein complement(1285222..1285416) Streptococcus thermophilus LMG 18311 3165391 YP_139879.1 CDS stu1453 NC_006448.1 1285392 1285580 R truncated; hypothetical protein complement(1285392..1285580) Streptococcus thermophilus LMG 18311 3165349 YP_139880.1 CDS stu1454 NC_006448.1 1285680 1285985 R truncated; hypothetical protein complement(1285680..1285985) Streptococcus thermophilus LMG 18311 3164198 YP_139881.1 CDS eutD NC_006448.1 1286014 1286997 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(1286014..1286997) Streptococcus thermophilus LMG 18311 3165456 YP_139882.1 CDS stu1456 NC_006448.1 1287011 1287907 R ribosomal large subunit pseudouridine synthase D complement(1287011..1287907) Streptococcus thermophilus LMG 18311 3164583 YP_139883.1 CDS ppnK NC_006448.1 1287904 1288743 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(1287904..1288743) Streptococcus thermophilus LMG 18311 3165088 YP_139884.1 CDS stu1459 NC_006448.1 1288712 1289437 R GTP pyrophosphokinase complement(1288712..1289437) Streptococcus thermophilus LMG 18311 3164221 YP_139885.1 CDS stu1458 NC_006448.1 1289401 1290057 D hypothetical protein 1289401..1290057 Streptococcus thermophilus LMG 18311 3165502 YP_139886.1 CDS prsA2 NC_006448.1 1290380 1291393 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1290380..1291393 Streptococcus thermophilus LMG 18311 3164515 YP_139887.1 CDS nifS3 NC_006448.1 1291397 1292509 D aminotransferase 1291397..1292509 Streptococcus thermophilus LMG 18311 3165208 YP_139888.1 CDS stu1462 NC_006448.1 1292511 1292858 D hypothetical protein 1292511..1292858 Streptococcus thermophilus LMG 18311 3165291 YP_139889.1 CDS stu1463 NC_006448.1 1292967 1293662 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1292967..1293662 Streptococcus thermophilus LMG 18311 3165405 YP_139890.1 CDS stu1464 NC_006448.1 1293655 1294350 D glutamine amidotransferase (class I) 1293655..1294350 Streptococcus thermophilus LMG 18311 3165334 YP_139891.1 CDS radC NC_006448.1 1294403 1295089 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1294403..1295089) Streptococcus thermophilus LMG 18311 3164219 YP_139892.1 CDS rgpF NC_006448.1 1295138 1296922 R polysaccharide biosynthesis protein complement(1295138..1296922) Streptococcus thermophilus LMG 18311 3165162 YP_139893.1 CDS rgpE NC_006448.1 1296919 1297974 R polysaccharide biosynthesis protein/ glycosyltransferase complement(1296919..1297974) Streptococcus thermophilus LMG 18311 3165529 YP_139894.1 CDS rgpD NC_006448.1 1297994 1299199 R polysaccharide ABC exporter ATP-binding protein complement(1297994..1299199) Streptococcus thermophilus LMG 18311 3165595 YP_139895.1 CDS rgpC NC_006448.1 1299199 1300029 R polysaccharide ABC exporter membrane-spanning protein complement(1299199..1300029) Streptococcus thermophilus LMG 18311 3163792 YP_139896.1 CDS rgpB NC_006448.1 1299992 1300948 R polysaccharide biosynthesis protein/ rhamnosyl transferase complement(1299992..1300948) Streptococcus thermophilus LMG 18311 3165531 YP_139897.1 CDS rgpA NC_006448.1 1300945 1302111 R polysaccharide biosynthesis protein/ rhamnosyl transferase complement(1300945..1302111) Streptococcus thermophilus LMG 18311 3163804 YP_139898.1 CDS rgpX2 NC_006448.1 1302202 1303212 R polysaccharide biosynthesis protein rhamnosyl transferase complement(1302202..1303212) Streptococcus thermophilus LMG 18311 3165520 YP_139899.1 CDS rgpX3 NC_006448.1 1303212 1304486 R polysaccharide biosynthesis protein transporter complement(1303212..1304486) Streptococcus thermophilus LMG 18311 3165333 YP_139900.1 CDS stu1481 NC_006448.1 1304479 1304811 R hypothetical protein complement(1304479..1304811) Streptococcus thermophilus LMG 18311 3165476 YP_139901.1 CDS stu1482 NC_006448.1 1304817 1305506 R glycosyltransferase complement(1304817..1305506) Streptococcus thermophilus LMG 18311 3165393 YP_139902.1 CDS rmlD NC_006448.1 1305589 1306461 R dTDP-4-keto-L-rhamnose reductase complement(1305589..1306461) Streptococcus thermophilus LMG 18311 3164725 YP_139903.1 CDS stu1484 NC_006448.1 1306517 1307863 R hypothetical protein complement(1306517..1307863) Streptococcus thermophilus LMG 18311 3164217 YP_139904.1 CDS stu1485 NC_006448.1 1307964 1308881 R glycosyl transferase family protein complement(1307964..1308881) Streptococcus thermophilus LMG 18311 3165446 YP_139905.1 CDS stu1486 NC_006448.1 1308944 1310359 R hypothetical protein complement(1308944..1310359) Streptococcus thermophilus LMG 18311 3165489 YP_139906.1 CDS stu1487 NC_006448.1 1310693 1311058 R hypothetical protein complement(1310693..1311058) Streptococcus thermophilus LMG 18311 3165486 YP_139907.1 CDS rpoD NC_006448.1 1311082 1312191 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD complement(1311082..1312191) Streptococcus thermophilus LMG 18311 3165306 YP_139908.1 CDS dnaG NC_006448.1 1312195 1314006 R synthesizes RNA primers at the replication forks; DNA primase complement(1312195..1314006) Streptococcus thermophilus LMG 18311 3164805 YP_139909.2 CDS rpsU NC_006448.1 1314377 1314553 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(1314377..1314553) Streptococcus thermophilus LMG 18311 3165607 YP_139910.1 CDS stu1492 NC_006448.1 1314748 1315542 R polar amino acid ABC uptake transporter substrate binding protein complement(1314748..1315542) Streptococcus thermophilus LMG 18311 3165394 YP_139911.1 CDS stu1493 NC_006448.1 1315635 1316747 R associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase complement(1315635..1316747) Streptococcus thermophilus LMG 18311 3165397 YP_139912.1 CDS stu1494 NC_006448.1 1317091 1317888 R polar amino acid ABC uptake transporter substrate binding protein complement(1317091..1317888) Streptococcus thermophilus LMG 18311 3164631 YP_139913.1 CDS stu1495 NC_006448.1 1317885 1318721 R polar amino acid ABC uptake transporter substrate binding protein complement(1317885..1318721) Streptococcus thermophilus LMG 18311 3165350 YP_139914.1 CDS stu1496 NC_006448.1 1318928 1319392 R MutT/nudix family protein complement(1318928..1319392) Streptococcus thermophilus LMG 18311 3165602 YP_139915.1 CDS uvrB NC_006448.1 1319437 1321443 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1319437..1321443) Streptococcus thermophilus LMG 18311 3165455 YP_139916.1 CDS stu1498 NC_006448.1 1321575 1322015 R hypothetical protein complement(1321575..1322015) Streptococcus thermophilus LMG 18311 3165376 YP_139917.1 CDS stu1499 NC_006448.1 1322188 1322538 R hypothetical protein complement(1322188..1322538) Streptococcus thermophilus LMG 18311 3165320 YP_139918.1 CDS stu1500 NC_006448.1 1322770 1323051 R hypothetical protein complement(1322770..1323051) Streptococcus thermophilus LMG 18311 3165323 YP_139919.1 CDS gnlP NC_006448.1 1323250 1325460 D glutamine ABC uptake transporter membrane-spanning protein 1323250..1325460 Streptococcus thermophilus LMG 18311 3165485 YP_139920.1 CDS gnlQ NC_006448.1 1325460 1326200 D glutamine ABC uptake transporter ATP-binding protein 1325460..1326200 Streptococcus thermophilus LMG 18311 3165315 YP_139921.1 CDS stu1503 NC_006448.1 1326273 1326470 R hypothetical protein complement(1326273..1326470) Streptococcus thermophilus LMG 18311 3164608 YP_139922.2 CDS obgE NC_006448.1 1326637 1327944 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1326637..1327944) Streptococcus thermophilus LMG 18311 3165454 YP_139923.1 CDS rsuA2 NC_006448.1 1328254 1328985 R ribosomal small subunit pseudouridine synthase A complement(1328254..1328985) Streptococcus thermophilus LMG 18311 3164848 YP_139924.1 CDS stu1506 NC_006448.1 1328986 1329219 R hypothetical protein complement(1328986..1329219) Streptococcus thermophilus LMG 18311 3165605 YP_139925.1 CDS stu1507 NC_006448.1 1329355 1329648 R hypothetical protein complement(1329355..1329648) Streptococcus thermophilus LMG 18311 3165601 YP_139926.1 CDS stu1508 NC_006448.1 1329669 1329770 D hypothetical protein 1329669..1329770 Streptococcus thermophilus LMG 18311 3165406 YP_139927.1 CDS stu1509 NC_006448.1 1329931 1330521 D hypothetical protein 1329931..1330521 Streptococcus thermophilus LMG 18311 3165292 YP_139928.1 CDS stu1510 NC_006448.1 1330521 1330847 D hypothetical protein 1330521..1330847 Streptococcus thermophilus LMG 18311 3165427 YP_139929.1 CDS stu1511 NC_006448.1 1331070 1331933 R MutR family transcriptional regulator complement(1331070..1331933) Streptococcus thermophilus LMG 18311 3165423 YP_139930.1 CDS stu1512 NC_006448.1 1332282 1333577 D hypothetical protein 1332282..1333577 Streptococcus thermophilus LMG 18311 3165500 YP_139931.1 CDS stu1513 NC_006448.1 1333579 1335150 D peptide-2 ABC transporter ATP binding/membrane-spanning protein 1333579..1335150 Streptococcus thermophilus LMG 18311 3165331 YP_139932.1 CDS stu1514 NC_006448.1 1335432 1335863 D hypothetical protein 1335432..1335863 Streptococcus thermophilus LMG 18311 3165084 YP_139933.1 CDS stu1515 NC_006448.1 1335890 1336258 D hypothetical protein 1335890..1336258 Streptococcus thermophilus LMG 18311 3165379 YP_139934.1 CDS stu1516 NC_006448.1 1336287 1336751 R hypothetical protein complement(1336287..1336751) Streptococcus thermophilus LMG 18311 3165414 YP_139935.1 CDS stu1517 NC_006448.1 1337768 1338658 D hypothetical protein 1337768..1338658 Streptococcus thermophilus LMG 18311 3164677 YP_139936.1 CDS stu1518 NC_006448.1 1338696 1338947 R hypothetical protein complement(1338696..1338947) Streptococcus thermophilus LMG 18311 3165448 YP_139937.1 CDS serB NC_006448.1 1339159 1339806 R phosphoserine phosphatase complement(1339159..1339806) Streptococcus thermophilus LMG 18311 3165319 YP_139938.1 CDS ezrA NC_006448.1 1339918 1341612 R acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA complement(1339918..1341612) Streptococcus thermophilus LMG 18311 3165318 YP_139939.1 CDS gyrB NC_006448.1 1341739 1343691 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(1341739..1343691) Streptococcus thermophilus LMG 18311 3165388 YP_139940.1 CDS stu1522 NC_006448.1 1343692 1344297 R HAD superfamily hydrolase complement(1343692..1344297) Streptococcus thermophilus LMG 18311 3165468 YP_139941.1 CDS stu1523 NC_006448.1 1344338 1345060 R hypothetical protein complement(1344338..1345060) Streptococcus thermophilus LMG 18311 3163781 YP_139942.1 CDS stu1524 NC_006448.1 1345026 1345424 R hypothetical protein complement(1345026..1345424) Streptococcus thermophilus LMG 18311 3165305 YP_139943.1 CDS stu1525 NC_006448.1 1345680 1346033 R hypothetical protein complement(1345680..1346033) Streptococcus thermophilus LMG 18311 3165459 YP_139944.1 CDS stu1526 NC_006448.1 1346068 1346295 R truncated; methylguanine-DNA methyltransferase, truncated complement(1346068..1346295) Streptococcus thermophilus LMG 18311 3165102 YP_139945.1 CDS serA NC_006448.1 1346619 1347797 R D-3-phosphoglycerate dehydrogenase complement(1346619..1347797) Streptococcus thermophilus LMG 18311 3165592 YP_139946.1 CDS stu1528 NC_006448.1 1347816 1348373 R acetyltransferase complement(1347816..1348373) Streptococcus thermophilus LMG 18311 3165591 YP_139947.1 CDS serC NC_006448.1 1348385 1349479 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1348385..1349479) Streptococcus thermophilus LMG 18311 3165038 YP_139948.1 CDS stu1530 NC_006448.1 1349633 1350295 R truncated; transcriptional regulator, truncated complement(1349633..1350295) Streptococcus thermophilus LMG 18311 3164790 YP_139949.1 CDS stu1531 NC_006448.1 1350276 1350539 R truncated; transcriptional regulator, truncated complement(1350276..1350539) Streptococcus thermophilus LMG 18311 3165506 YP_139950.1 CDS gloA NC_006448.1 1350585 1350980 D glyoxalase I/lactoylglutathione lyase 1350585..1350980 Streptococcus thermophilus LMG 18311 3165401 YP_139951.1 CDS stu1533 NC_006448.1 1351024 1351542 R truncated; hypothetical protein complement(1351024..1351542) Streptococcus thermophilus LMG 18311 3165382 YP_139952.1 CDS stu1534 NC_006448.1 1351597 1351773 R truncated; hypothetical protein complement(1351597..1351773) Streptococcus thermophilus LMG 18311 3164215 YP_139953.1 CDS potD NC_006448.1 1352121 1353191 R putrescine/spermidine ABC transporter subtrate-binding protein complement(1352121..1353191) Streptococcus thermophilus LMG 18311 3164214 YP_139954.1 CDS potC NC_006448.1 1353181 1353984 R spermidine/putrescine ABC transporter permease complement(1353181..1353984) Streptococcus thermophilus LMG 18311 3165330 YP_139955.1 CDS potB NC_006448.1 1353957 1354772 R spermidine/putrescine ABC transporter permease complement(1353957..1354772) Streptococcus thermophilus LMG 18311 3165241 YP_139956.1 CDS potA NC_006448.1 1354735 1355889 R putrescine/spermidine ABC transporter ATP-binding protein complement(1354735..1355889) Streptococcus thermophilus LMG 18311 3165483 YP_139957.1 CDS murB NC_006448.1 1355934 1356911 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1355934..1356911) Streptococcus thermophilus LMG 18311 3164898 YP_139958.1 CDS folK NC_006448.1 1357026 1357517 R hydroxymethylpterin pyrophosphokinase complement(1357026..1357517) Streptococcus thermophilus LMG 18311 3165398 YP_139959.1 CDS folQ NC_006448.1 1357514 1357873 R dihydroneopterin aldolase complement(1357514..1357873) Streptococcus thermophilus LMG 18311 3165499 YP_139960.1 CDS amyL NC_006448.1 1358070 1359545 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1358070..1359545 Streptococcus thermophilus LMG 18311 3163852 YP_139961.1 CDS folP NC_006448.1 1359577 1360377 R dihydropteroate synthase complement(1359577..1360377) Streptococcus thermophilus LMG 18311 3165593 YP_139962.1 CDS folE NC_006448.1 1360406 1360969 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(1360406..1360969) Streptococcus thermophilus LMG 18311 3165556 YP_139963.1 CDS stu1545 NC_006448.1 1361115 1362959 R hypothetical protein complement(1361115..1362959) Streptococcus thermophilus LMG 18311 3164930 YP_139964.1 CDS folC2 NC_006448.1 1363023 1364285 R folylpolyglutamate synthase / dihydrofolate synthase complement(1363023..1364285) Streptococcus thermophilus LMG 18311 3165555 YP_139965.1 CDS stu1547 NC_006448.1 1364428 1364676 R hypothetical protein complement(1364428..1364676) Streptococcus thermophilus LMG 18311 3163832 YP_139966.1 CDS rpsP NC_006448.1 1364688 1364960 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1364688..1364960) Streptococcus thermophilus LMG 18311 3165345 YP_139967.1 CDS tehB NC_006448.1 1365393 1366271 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1365393..1366271 Streptococcus thermophilus LMG 18311 3164104 YP_139968.1 CDS exoA NC_006448.1 1367425 1368252 D 3'-exo-deoxyribonuclease 1367425..1368252 Streptococcus thermophilus LMG 18311 3165610 YP_139969.1 CDS stu1551 NC_006448.1 1368326 1368805 D hypothetical protein 1368326..1368805 Streptococcus thermophilus LMG 18311 3165519 YP_139970.1 CDS stu1552 NC_006448.1 1368925 1369563 R truncated; hypothetical protein complement(1368925..1369563) Streptococcus thermophilus LMG 18311 3165419 YP_139971.1 CDS stu1553 NC_006448.1 1369754 1370767 R similar to YegS from E. coli; lipid kinase complement(1369754..1370767) Streptococcus thermophilus LMG 18311 3165507 YP_139972.1 CDS ligA NC_006448.1 1370777 1372735 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1370777..1372735) Streptococcus thermophilus LMG 18311 3165441 YP_139973.1 CDS stu1555 NC_006448.1 1372786 1373307 R hypothetical protein complement(1372786..1373307) Streptococcus thermophilus LMG 18311 3165496 YP_139974.1 CDS stu1556 NC_006448.1 1373386 1374351 R tRNA-processing ribonuclease BN complement(1373386..1374351) Streptococcus thermophilus LMG 18311 3165433 YP_139975.1 CDS pepM NC_006448.1 1374353 1375213 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase complement(1374353..1375213) Streptococcus thermophilus LMG 18311 3165390 YP_139976.1 CDS stu1558 NC_006448.1 1375257 1376555 R hypothetical protein complement(1375257..1376555) Streptococcus thermophilus LMG 18311 3164207 YP_139977.1 CDS stu1559 NC_006448.1 1376530 1377117 R acetyltransferase complement(1376530..1377117) Streptococcus thermophilus LMG 18311 3165505 YP_139978.1 CDS murZ NC_006448.1 1377141 1378412 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1377141..1378412) Streptococcus thermophilus LMG 18311 3165263 YP_139979.1 CDS comEC NC_006448.1 1378489 1380729 R late competence protein required for DNA uptake complement(1378489..1380729) Streptococcus thermophilus LMG 18311 3163847 YP_139980.1 CDS comEA NC_006448.1 1380719 1381414 R late competence protein required for DNA binding and uptake complement(1380719..1381414) Streptococcus thermophilus LMG 18311 3165396 YP_139981.1 CDS stu1563 NC_006448.1 1381522 1382277 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1381522..1382277) Streptococcus thermophilus LMG 18311 3165369 YP_139982.1 CDS stu1564 NC_006448.1 1382477 1383010 D truncated; peptidoglycan GlcNAc deacetylase, truncated 1382477..1383010 Streptococcus thermophilus LMG 18311 3165564 YP_139983.1 CDS stu1565 NC_006448.1 1383055 1383342 D truncated; peptidoglycan GlcNAc deacetylase, truncated 1383055..1383342 Streptococcus thermophilus LMG 18311 3165422 YP_139984.1 CDS stu1566 NC_006448.1 1383392 1384156 D hypothetical protein 1383392..1384156 Streptococcus thermophilus LMG 18311 3165571 YP_139985.1 CDS stu1567 NC_006448.1 1384160 1384429 D hypothetical protein 1384160..1384429 Streptococcus thermophilus LMG 18311 3165568 YP_139986.1 CDS rheA NC_006448.1 1384986 1386572 R ATP-dependent RNA helicase complement(1384986..1386572) Streptococcus thermophilus LMG 18311 3165273 YP_139987.1 CDS corA1 NC_006448.1 1386763 1387671 R magnesium/cobalt transporter CorA complement(1386763..1387671) Streptococcus thermophilus LMG 18311 3165357 YP_139988.1 CDS stu1570 NC_006448.1 1387685 1388065 R hypothetical protein complement(1387685..1388065) Streptococcus thermophilus LMG 18311 3164872 YP_139989.1 CDS stu1571 NC_006448.1 1388366 1388941 D hypothetical protein 1388366..1388941 Streptococcus thermophilus LMG 18311 3164483 YP_139990.1 CDS stu1572 NC_006448.1 1389392 1390255 D MutR family transcriptional regulator 1389392..1390255 Streptococcus thermophilus LMG 18311 3165220 YP_139991.1 CDS stu1573 NC_006448.1 1390372 1391550 D hypothetical protein 1390372..1391550 Streptococcus thermophilus LMG 18311 3165512 YP_139992.1 CDS prfC NC_006448.1 1391796 1393340 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(1391796..1393340) Streptococcus thermophilus LMG 18311 3165514 YP_139993.1 CDS stu1575 NC_006448.1 1393691 1394356 R hypothetical protein complement(1393691..1394356) Streptococcus thermophilus LMG 18311 3164184 YP_139994.1 CDS murF NC_006448.1 1394445 1395818 R UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-- D-alanyl-D-alanine ligase complement(1394445..1395818) Streptococcus thermophilus LMG 18311 3164421 YP_139995.1 CDS stu1577 NC_006448.1 1396065 1396658 D hypothetical protein 1396065..1396658 Streptococcus thermophilus LMG 18311 3163772 YP_139996.1 CDS stu1578 NC_006448.1 1396627 1397169 D hypothetical protein 1396627..1397169 Streptococcus thermophilus LMG 18311 3164970 YP_139997.1 CDS stu1579 NC_006448.1 1397408 1398262 R polar amino acid ABC uptake transporter substrate binding protein complement(1397408..1398262) Streptococcus thermophilus LMG 18311 3164411 YP_139998.1 CDS stu1580 NC_006448.1 1398305 1399126 R polar amino acid ABC uptake transporter ATP-binding protein complement(1398305..1399126) Streptococcus thermophilus LMG 18311 3165574 YP_139999.1 CDS stu1581 NC_006448.1 1399065 1399760 R polar amino acid ABC uptake transporter membrane-spanning protein complement(1399065..1399760) Streptococcus thermophilus LMG 18311 3164272 YP_140000.1 CDS stu1582 NC_006448.1 1399702 1400382 R polar amino acid ABC uptake transporter membrane-spanning protein complement(1399702..1400382) Streptococcus thermophilus LMG 18311 3165497 YP_140001.1 CDS ddl NC_006448.1 1400707 1401753 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1400707..1401753) Streptococcus thermophilus LMG 18311 3165560 YP_140002.1 CDS copZ NC_006448.1 1401915 1402118 R copper chaperone - Cu2+-Cu+-Ag+-P-type ATPase complement(1401915..1402118) Streptococcus thermophilus LMG 18311 3163810 YP_140003.1 CDS copA NC_006448.1 1402193 1404421 R Cu2+-Cu+-Ag+-P-type ATPase complement(1402193..1404421) Streptococcus thermophilus LMG 18311 3165059 YP_140004.1 CDS copY NC_006448.1 1404425 1404856 R negative transcriptional regulator - copper transport operon complement(1404425..1404856) Streptococcus thermophilus LMG 18311 3164177 YP_140005.1 CDS trpA NC_006448.1 1405000 1405782 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1405000..1405782) Streptococcus thermophilus LMG 18311 3163859 YP_140006.1 CDS trpB NC_006448.1 1405786 1406994 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1405786..1406994) Streptococcus thermophilus LMG 18311 3165265 YP_140007.1 CDS trpF NC_006448.1 1406991 1407602 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(1406991..1407602) Streptococcus thermophilus LMG 18311 3164556 YP_140008.1 CDS trpC NC_006448.1 1407559 1408326 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase complement(1407559..1408326) Streptococcus thermophilus LMG 18311 3164172 YP_140009.1 CDS trpD NC_006448.1 1408323 1409327 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1408323..1409327) Streptococcus thermophilus LMG 18311 3163878 YP_140010.1 CDS trpG NC_006448.1 1409418 1409984 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1409418..1409984) Streptococcus thermophilus LMG 18311 3164756 YP_140011.1 CDS trpE NC_006448.1 1409981 1411351 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1409981..1411351) Streptococcus thermophilus LMG 18311 3165577 YP_140012.1 CDS stu1594 NC_006448.1 1411413 1411703 R hypothetical protein complement(1411413..1411703) Streptococcus thermophilus LMG 18311 3163794 YP_140013.1 CDS stu1595 NC_006448.1 1412289 1412639 R hypothetical protein complement(1412289..1412639) Streptococcus thermophilus LMG 18311 3165513 YP_140014.1 CDS ctpE NC_006448.1 1412721 1415108 R cation-P-type ATPase complement(1412721..1415108) Streptococcus thermophilus LMG 18311 3165351 YP_140015.1 CDS stu1597 NC_006448.1 1415341 1415736 R hypothetical protein complement(1415341..1415736) Streptococcus thermophilus LMG 18311 3164140 YP_140016.1 CDS stu1598 NC_006448.1 1416045 1416344 D hypothetical protein 1416045..1416344 Streptococcus thermophilus LMG 18311 3164376 YP_140017.1 CDS stu1599 NC_006448.1 1416502 1416792 R hypothetical protein complement(1416502..1416792) Streptococcus thermophilus LMG 18311 3164174 YP_140018.1 CDS stu1600 NC_006448.1 1416898 1417638 R MerR family transcriptional regulator complement(1416898..1417638) Streptococcus thermophilus LMG 18311 3165140 YP_140019.1 CDS dnaQ NC_006448.1 1417802 1418392 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1417802..1418392) Streptococcus thermophilus LMG 18311 3165235 YP_140020.1 CDS stu1602 NC_006448.1 1418442 1418978 R hypothetical protein complement(1418442..1418978) Streptococcus thermophilus LMG 18311 3165256 YP_140021.1 CDS stu1603 NC_006448.1 1419423 1419842 D hypothetical protein 1419423..1419842 Streptococcus thermophilus LMG 18311 3165232 YP_140022.1 CDS ilvD1 NC_006448.1 1419990 1421708 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1419990..1421708) Streptococcus thermophilus LMG 18311 3164723 YP_140023.1 CDS stu1605 NC_006448.1 1421821 1423002 D hypothetical protein 1421821..1423002 Streptococcus thermophilus LMG 18311 3164789 YP_140024.1 CDS trmB NC_006448.1 1423238 1423879 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(1423238..1423879) Streptococcus thermophilus LMG 18311 3165242 YP_140025.1 CDS stu1607 NC_006448.1 1423889 1424680 R hypothetical protein complement(1423889..1424680) Streptococcus thermophilus LMG 18311 3164170 YP_140026.1 CDS stu1608 NC_006448.1 1424738 1425775 R ABC transporter membrane-spanning protein complement(1424738..1425775) Streptococcus thermophilus LMG 18311 3165251 YP_140027.1 CDS stu1609 NC_006448.1 1425772 1426503 R ABC transporter ATP binding protein complement(1425772..1426503) Streptococcus thermophilus LMG 18311 3164741 YP_140028.1 CDS hit NC_006448.1 1426568 1426987 D cell cycle regulation histidine triad (HIT) protein 1426568..1426987 Streptococcus thermophilus LMG 18311 3164855 YP_140029.1 CDS stu1611 NC_006448.1 1426984 1427292 D hypothetical protein 1426984..1427292 Streptococcus thermophilus LMG 18311 3163744 YP_140030.1 CDS stu1612 NC_006448.1 1427844 1428014 R hypothetical protein complement(1427844..1428014) Streptococcus thermophilus LMG 18311 3165243 YP_140031.1 CDS stu1613 NC_006448.1 1428084 1428719 R hypothetical protein complement(1428084..1428719) Streptococcus thermophilus LMG 18311 3165245 YP_140032.1 CDS clpL NC_006448.1 1429272 1431371 R ATP-dependent proteinase ATP-binding subunit complement(1429272..1431371) Streptococcus thermophilus LMG 18311 3165508 YP_140033.1 CDS stu1615 NC_006448.1 1432086 1433177 R hypothetical protein complement(1432086..1433177) Streptococcus thermophilus LMG 18311 3164237 YP_140034.1 CDS stu1616 NC_006448.1 1433184 1434053 R hypothetical protein complement(1433184..1434053) Streptococcus thermophilus LMG 18311 3165217 YP_140035.1 CDS stu1617 NC_006448.1 1434249 1434602 R hypothetical protein complement(1434249..1434602) Streptococcus thermophilus LMG 18311 3164920 YP_140036.1 CDS stu1618 NC_006448.1 1434626 1435216 R hypothetical protein complement(1434626..1435216) Streptococcus thermophilus LMG 18311 3165523 YP_140037.1 CDS nadD NC_006448.1 1435213 1435845 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1435213..1435845) Streptococcus thermophilus LMG 18311 3164760 YP_140038.1 CDS stu1620 NC_006448.1 1435949 1436266 R hypothetical protein complement(1435949..1436266) Streptococcus thermophilus LMG 18311 3165295 YP_140039.1 CDS stu1621 NC_006448.1 1436505 1437623 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1436505..1437623) Streptococcus thermophilus LMG 18311 3165565 YP_140040.1 CDS stu1622 NC_006448.1 1437623 1438150 R hypothetical protein complement(1437623..1438150) Streptococcus thermophilus LMG 18311 3165125 YP_140041.1 CDS stu1623 NC_006448.1 1438287 1439201 R drug/metabolite transporter (DMT) superfamily protein complement(1438287..1439201) Streptococcus thermophilus LMG 18311 3165298 YP_140042.1 CDS stu1624 NC_006448.1 1439278 1439661 R hypothetical protein complement(1439278..1439661) Streptococcus thermophilus LMG 18311 3165494 YP_140043.1 CDS gatB NC_006448.1 1439759 1441201 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1439759..1441201) Streptococcus thermophilus LMG 18311 3163931 YP_140044.1 CDS gatA NC_006448.1 1441201 1442667 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1441201..1442667) Streptococcus thermophilus LMG 18311 3165268 YP_140045.2 CDS gatC NC_006448.1 1442667 1442969 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(1442667..1442969) Streptococcus thermophilus LMG 18311 3165222 YP_140046.1 CDS stu1628 NC_006448.1 1443109 1443363 R hypothetical protein complement(1443109..1443363) Streptococcus thermophilus LMG 18311 3165420 YP_140047.1 CDS stu1629 NC_006448.1 1443376 1443585 R hypothetical protein complement(1443376..1443585) Streptococcus thermophilus LMG 18311 3165576 YP_140048.1 CDS stu1630 NC_006448.1 1443901 1444227 R truncated; 6-phospho-beta-glucosidase complement(1443901..1444227) Streptococcus thermophilus LMG 18311 3165466 YP_140049.1 CDS stu1631 NC_006448.1 1444311 1445234 R truncated; 6-phospho-beta-glucosidase complement(1444311..1445234) Streptococcus thermophilus LMG 18311 3165426 YP_140050.1 CDS msrA2 NC_006448.1 1445500 1446027 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(1445500..1446027) Streptococcus thermophilus LMG 18311 3165266 YP_140051.1 CDS stu1633 NC_006448.1 1446021 1446872 R lipoprotein complement(1446021..1446872) Streptococcus thermophilus LMG 18311 3164743 YP_140052.1 CDS entB NC_006448.1 1446992 1447543 R pyrazinamidase/nicotinamidase complement(1446992..1447543) Streptococcus thermophilus LMG 18311 3164810 YP_140053.1 CDS codY NC_006448.1 1447606 1448391 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1447606..1448391) Streptococcus thermophilus LMG 18311 3165478 YP_140054.1 CDS aspC2 NC_006448.1 1448651 1449865 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase complement(1448651..1449865) Streptococcus thermophilus LMG 18311 3165449 YP_140055.1 CDS stu1637 NC_006448.1 1450220 1450672 D hypothetical protein 1450220..1450672 Streptococcus thermophilus LMG 18311 3165237 YP_140056.1 CDS stu1638 NC_006448.1 1451006 1451260 D truncated; hypothetical protein 1451006..1451260 Streptococcus thermophilus LMG 18311 3164905 YP_140057.1 CDS stu1639 NC_006448.1 1451729 1452109 R hypothetical protein complement(1451729..1452109) Streptococcus thermophilus LMG 18311 3165425 YP_140058.1 CDS pflA NC_006448.1 1452315 1453115 R pyruvate-formate lyase activating enzyme complement(1452315..1453115) Streptococcus thermophilus LMG 18311 3165236 YP_140059.1 CDS hlyX NC_006448.1 1454111 1455442 R hypothetical protein complement(1454111..1455442) Streptococcus thermophilus LMG 18311 3165262 YP_140060.1 CDS stu1642 NC_006448.1 1455555 1456337 D ABC transporter ATP binding protein 1455555..1456337 Streptococcus thermophilus LMG 18311 3165380 YP_140061.1 CDS nha NC_006448.1 1456956 1459022 R Na+:H+ antiporter complement(1456956..1459022) Streptococcus thermophilus LMG 18311 3165464 YP_140062.1 CDS stu1644 NC_006448.1 1459031 1459273 R hypothetical protein complement(1459031..1459273) Streptococcus thermophilus LMG 18311 3165229 YP_140063.1 CDS stu1645 NC_006448.1 1459270 1459818 R rRNA methylase complement(1459270..1459818) Streptococcus thermophilus LMG 18311 3165267 YP_140064.1 CDS stu1646 NC_006448.1 1459815 1460759 R hypothetical protein complement(1459815..1460759) Streptococcus thermophilus LMG 18311 3165211 YP_140065.1 CDS stu1647 NC_006448.1 1460844 1461920 R protease complement(1460844..1461920) Streptococcus thermophilus LMG 18311 3165596 YP_140066.1 CDS coaD NC_006448.1 1461898 1462395 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1461898..1462395) Streptococcus thermophilus LMG 18311 3165530 YP_140067.1 CDS stu1649 NC_006448.1 1462429 1462977 R methyltransferase complement(1462429..1462977) Streptococcus thermophilus LMG 18311 3165504 YP_140068.1 CDS trxB1 NC_006448.1 1463119 1464039 R thioredoxin reductase complement(1463119..1464039) Streptococcus thermophilus LMG 18311 3164148 YP_140069.1 CDS stu1651 NC_006448.1 1464105 1464329 R hypothetical protein complement(1464105..1464329) Streptococcus thermophilus LMG 18311 3165238 YP_140070.1 CDS stu1652 NC_006448.1 1464544 1465287 R polar amino acid ABC uptake transporter ATP-binding protein complement(1464544..1465287) Streptococcus thermophilus LMG 18311 3165233 YP_140071.1 CDS stu1653 NC_006448.1 1465287 1466258 R polar amino acid ABC uptake transporter membrane-spanning protein complement(1465287..1466258) Streptococcus thermophilus LMG 18311 3165575 YP_140072.1 CDS stu1654 NC_006448.1 1466427 1467281 R polar amino acid ABC uptake transporter substrate binding protein complement(1466427..1467281) Streptococcus thermophilus LMG 18311 3164144 YP_140073.1 CDS stu1655 NC_006448.1 1467717 1467950 R hypothetical protein complement(1467717..1467950) Streptococcus thermophilus LMG 18311 3164825 YP_140074.1 CDS dinP NC_006448.1 1468248 1469351 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1468248..1469351) Streptococcus thermophilus LMG 18311 3163894 YP_140075.1 CDS pfl NC_006448.1 1469630 1471939 D pyruvate formate-lyase 1469630..1471939 Streptococcus thermophilus LMG 18311 3165358 YP_140076.1 CDS cah NC_006448.1 1472202 1472984 D carbonate dehydratase 1472202..1472984 Streptococcus thermophilus LMG 18311 3165622 YP_140077.1 CDS stu1659 NC_006448.1 1473002 1473487 D hypothetical protein 1473002..1473487 Streptococcus thermophilus LMG 18311 3165257 YP_140078.1 CDS stu1660 NC_006448.1 1473839 1474144 R truncated; type I restriction-modification system specificty subunit, truncated complement(1473839..1474144) Streptococcus thermophilus LMG 18311 3165285 YP_140079.1 CDS stu1661 NC_006448.1 1474163 1474453 R truncated; plasmid mobilization protein, truncated complement(1474163..1474453) Streptococcus thermophilus LMG 18311 3165301 YP_140080.1 CDS stu1662 NC_006448.1 1474458 1474676 R truncated; plasmid mobilization protein, truncated complement(1474458..1474676) Streptococcus thermophilus LMG 18311 3165491 YP_140081.1 CDS int NC_006448.1 1475158 1475619 R integrase/recombinase plasmid associated complement(1475158..1475619) Streptococcus thermophilus LMG 18311 3164007 YP_140082.1 CDS stu1664 NC_006448.1 1475839 1476525 R hypothetical protein complement(1475839..1476525) Streptococcus thermophilus LMG 18311 3163775 YP_140083.1 CDS stu1665 NC_006448.1 1476601 1477356 R hypothetical protein complement(1476601..1477356) Streptococcus thermophilus LMG 18311 3165219 YP_140084.1 CDS stu1666 NC_006448.1 1477353 1478003 R ABC transporter ATP binding protein complement(1477353..1478003) Streptococcus thermophilus LMG 18311 3164139 YP_140085.1 CDS stu1667 NC_006448.1 1478205 1479176 R hypothetical protein complement(1478205..1479176) Streptococcus thermophilus LMG 18311 3165118 YP_140086.1 CDS cppA NC_006448.1 1479161 1479928 R C3-degrading proteinase complement(1479161..1479928) Streptococcus thermophilus LMG 18311 3164137 YP_140087.1 CDS stu1670 NC_006448.1 1480088 1480474 D hypothetical protein 1480088..1480474 Streptococcus thermophilus LMG 18311 3165435 YP_140088.1 CDS gla NC_006448.1 1480648 1481511 R glycerol facilitator complement(1480648..1481511) Streptococcus thermophilus LMG 18311 3165439 YP_140089.1 CDS pepXP NC_006448.1 1481632 1483899 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1481632..1483899 Streptococcus thermophilus LMG 18311 3164134 YP_140090.1 CDS blpX NC_006448.1 1483979 1484359 R bacteriocin self-immunity protein complement(1483979..1484359) Streptococcus thermophilus LMG 18311 3165275 YP_140091.1 CDS stu1674 NC_006448.1 1484484 1484747 R hypothetical protein complement(1484484..1484747) Streptococcus thermophilus LMG 18311 3165532 YP_140092.1 CDS blpI NC_006448.1 1485069 1485365 R immunity protein complement(1485069..1485365) Streptococcus thermophilus LMG 18311 3165296 YP_140093.1 CDS blpT NC_006448.1 1485530 1486462 R hypothetical protein complement(1485530..1486462) Streptococcus thermophilus LMG 18311 3165254 YP_140094.1 CDS tnpSth1 NC_006448.1 1486599 1487339 D IS3 familytransposase orf1 1486599..1487339 Streptococcus thermophilus LMG 18311 3165246 YP_140095.1 CDS tnpSth1 NC_006448.1 1487354 1488223 D IS3 familytransposase orf2 1487354..1488223 Streptococcus thermophilus LMG 18311 3164133 YP_140096.1 CDS stu1680 NC_006448.1 1488470 1488610 R truncated; pore-forming peptide, truncated complement(1488470..1488610) Streptococcus thermophilus LMG 18311 3165231 YP_140097.1 CDS stu1681 NC_006448.1 1488861 1489262 R hypothetical protein complement(1488861..1489262) Streptococcus thermophilus LMG 18311 3165264 YP_140098.1 CDS stu1682 NC_006448.1 1489388 1489588 R hypothetical protein complement(1489388..1489588) Streptococcus thermophilus LMG 18311 3165223 YP_140099.1 CDS stu1683 NC_006448.1 1489592 1489759 R hypothetical protein complement(1489592..1489759) Streptococcus thermophilus LMG 18311 3165418 YP_140100.1 CDS stu1684 NC_006448.1 1489856 1490029 R hypothetical protein complement(1489856..1490029) Streptococcus thermophilus LMG 18311 3165159 YP_140101.1 CDS blpU NC_006448.1 1490249 1490479 R pore-forming peptide bacteriocin complement(1490249..1490479) Streptococcus thermophilus LMG 18311 3165122 YP_140102.1 CDS rr09 NC_006448.1 1490729 1491460 D response regulator 1490729..1491460 Streptococcus thermophilus LMG 18311 3165248 YP_140103.1 CDS hk09 NC_006448.1 1491460 1492800 D sensor histidine kinase 1491460..1492800 Streptococcus thermophilus LMG 18311 3165250 YP_140104.1 CDS blpC NC_006448.1 1492818 1492979 R signal peptide complement(1492818..1492979) Streptococcus thermophilus LMG 18311 3165225 YP_140105.1 CDS stu1689 NC_006448.1 1492994 1493899 R truncated; bacteriocin ABC exporter accessory protein, truncated complement(1492994..1493899) Streptococcus thermophilus LMG 18311 3165260 YP_140106.1 CDS stu1690 NC_006448.1 1494027 1494362 R truncated; bacteriocin ABC exporter accessory protein, truncated complement(1494027..1494362) Streptococcus thermophilus LMG 18311 3164152 YP_140107.1 CDS blpA NC_006448.1 1494378 1496546 R bacteriocin ABC transporter ATP binding protein complement(1494378..1496546) Streptococcus thermophilus LMG 18311 3165209 YP_140108.1 CDS stu1692 NC_006448.1 1496966 1497217 D hypothetical protein 1496966..1497217 Streptococcus thermophilus LMG 18311 3165070 YP_140109.1 CDS stu1693 NC_006448.1 1497545 1499290 R lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein complement(1497545..1499290) Streptococcus thermophilus LMG 18311 3165230 YP_140110.1 CDS stu1694 NC_006448.1 1499283 1501040 R lipid/multidrug/protein-type ABC exporter ATP binding/membrane-spanning protein complement(1499283..1501040) Streptococcus thermophilus LMG 18311 3164294 YP_140111.1 CDS stu1695 NC_006448.1 1501639 1502166 R hypothetical protein complement(1501639..1502166) Streptococcus thermophilus LMG 18311 3165352 YP_140112.1 CDS stu1696 NC_006448.1 1502168 1503337 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1502168..1503337) Streptococcus thermophilus LMG 18311 3165215 YP_140113.1 CDS stu1697 NC_006448.1 1503341 1504063 R hypothetical protein complement(1503341..1504063) Streptococcus thermophilus LMG 18311 3165562 YP_140114.1 CDS stu1698 NC_006448.1 1504118 1505473 R hypothetical protein complement(1504118..1505473) Streptococcus thermophilus LMG 18311 3165244 YP_140115.1 CDS rheB NC_006448.1 1506322 1507665 R ATP-dependent RNA helicase complement(1506322..1507665) Streptococcus thermophilus LMG 18311 3165212 YP_140116.1 CDS mraY NC_006448.1 1507740 1508762 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1507740..1508762) Streptococcus thermophilus LMG 18311 3165249 YP_140117.1 CDS pbp2X NC_006448.1 1508764 1511031 R penicillin binding protein 2X complement(1508764..1511031) Streptococcus thermophilus LMG 18311 3165253 YP_140118.1 CDS ftsL NC_006448.1 1511035 1511355 R cell division protein complement(1511035..1511355) Streptococcus thermophilus LMG 18311 3165279 YP_140119.1 CDS mraW NC_006448.1 1511358 1512422 R S-adenosyl-methyltransferase MraW complement(1511358..1512422) Streptococcus thermophilus LMG 18311 3165541 YP_140120.1 CDS stu1704 NC_006448.1 1512476 1513471 R hypothetical protein complement(1512476..1513471) Streptococcus thermophilus LMG 18311 3165599 YP_140121.1 CDS stu1707 NC_006448.1 1513739 1513834 R hypothetical protein complement(1513739..1513834) Streptococcus thermophilus LMG 18311 3164122 YP_140122.1 CDS stu1708 NC_006448.1 1514108 1514464 R hypothetical protein complement(1514108..1514464) Streptococcus thermophilus LMG 18311 3165227 YP_140123.1 CDS stu1709 NC_006448.1 1514684 1514953 R hypothetical protein complement(1514684..1514953) Streptococcus thermophilus LMG 18311 3165247 YP_140124.1 CDS proA NC_006448.1 1515334 1516584 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1515334..1516584) Streptococcus thermophilus LMG 18311 3165228 YP_140125.1 CDS proB NC_006448.1 1516586 1517389 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1516586..1517389) Streptococcus thermophilus LMG 18311 3165308 YP_140126.1 CDS stu1712 NC_006448.1 1517510 1519099 R hypothetical protein complement(1517510..1519099) Streptococcus thermophilus LMG 18311 3165539 YP_140127.1 CDS stu1713 NC_006448.1 1519102 1519602 R truncated; ABC transporter ATP binding protein, truncated complement(1519102..1519602) Streptococcus thermophilus LMG 18311 3163916 YP_140128.1 CDS stu1714 NC_006448.1 1519556 1519834 R truncated; ABC transporter ATP binding protein, truncated complement(1519556..1519834) Streptococcus thermophilus LMG 18311 3165527 YP_140129.1 CDS stu1715 NC_006448.1 1520108 1520737 D hypothetical protein 1520108..1520737 Streptococcus thermophilus LMG 18311 3165214 YP_140130.1 CDS rexA NC_006448.1 1521235 1524888 R ATP-dependent exonuclease subunit A complement(1521235..1524888) Streptococcus thermophilus LMG 18311 3165569 YP_140131.1 CDS rexB NC_006448.1 1524878 1528198 R ATP-dependent exonuclease subunit B complement(1524878..1528198) Streptococcus thermophilus LMG 18311 3165558 YP_140132.1 CDS stu1718 NC_006448.1 1528887 1529339 R hypothetical protein complement(1528887..1529339) Streptococcus thermophilus LMG 18311 3165528 YP_140133.1 CDS stu1719 NC_006448.1 1529682 1529822 R hypothetical protein complement(1529682..1529822) Streptococcus thermophilus LMG 18311 3165259 YP_140134.1 CDS stu1720 NC_006448.1 1530040 1530660 R hypothetical protein complement(1530040..1530660) Streptococcus thermophilus LMG 18311 3165472 YP_140135.1 CDS stu1721 NC_006448.1 1531122 1531988 R hypothetical protein complement(1531122..1531988) Streptococcus thermophilus LMG 18311 3165210 YP_140136.1 CDS stu1722 NC_006448.1 1531975 1532202 R hypothetical protein complement(1531975..1532202) Streptococcus thermophilus LMG 18311 3165553 YP_140137.1 CDS stu1723 NC_006448.1 1532262 1533647 R hypothetical protein complement(1532262..1533647) Streptococcus thermophilus LMG 18311 3165434 YP_140138.1 CDS ansB NC_006448.1 1533718 1534686 D L-asparaginase 1533718..1534686 Streptococcus thermophilus LMG 18311 3164329 YP_140139.1 CDS recG NC_006448.1 1535455 1537473 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1535455..1537473) Streptococcus thermophilus LMG 18311 3163752 YP_140140.1 CDS alr NC_006448.1 1537602 1538705 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1537602..1538705) Streptococcus thermophilus LMG 18311 3165218 YP_140141.1 CDS acpS NC_006448.1 1538726 1539085 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1538726..1539085) Streptococcus thermophilus LMG 18311 3165239 YP_140142.1 CDS aroG1 NC_006448.1 1539089 1540120 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1539089..1540120) Streptococcus thermophilus LMG 18311 3165579 YP_140143.1 CDS aroG2 NC_006448.1 1540218 1541249 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1540218..1541249) Streptococcus thermophilus LMG 18311 3165269 YP_140144.1 CDS secA NC_006448.1 1541273 1543822 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1541273..1543822) Streptococcus thermophilus LMG 18311 3164802 YP_140145.1 CDS stu1731 NC_006448.1 1544005 1544262 R hypothetical protein complement(1544005..1544262) Streptococcus thermophilus LMG 18311 3165550 YP_140146.1 CDS pmi1 NC_006448.1 1544349 1545296 R mannose-6-phosphate isomerase complement(1544349..1545296) Streptococcus thermophilus LMG 18311 3165258 YP_140147.1 CDS scrK NC_006448.1 1545362 1546255 R fructokinase complement(1545362..1546255) Streptococcus thermophilus LMG 18311 3165566 YP_140148.1 CDS scrA NC_006448.1 1546440 1548386 R sucrose PTS component II complement(1546440..1548386) Streptococcus thermophilus LMG 18311 3165536 YP_140149.1 CDS scrB NC_006448.1 1548530 1549972 D sucrose-6-phosphate hydrolase 1548530..1549972 Streptococcus thermophilus LMG 18311 3164935 YP_140150.1 CDS stu1736 NC_006448.1 1549981 1550211 D truncated; sucrose regulon regulatory protein, truncated 1549981..1550211 Streptococcus thermophilus LMG 18311 3165429 YP_140151.1 CDS stu1737 NC_006448.1 1550305 1550946 D truncated; sucrose regulon regulatory protein, truncated 1550305..1550946 Streptococcus thermophilus LMG 18311 3164318 YP_140152.1 CDS nusB NC_006448.1 1551036 1551470 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(1551036..1551470) Streptococcus thermophilus LMG 18311 3164774 YP_140153.1 CDS stu1739 NC_006448.1 1551463 1551894 R hypothetical protein complement(1551463..1551894) Streptococcus thermophilus LMG 18311 3165049 YP_140154.1 CDS efp NC_006448.1 1551923 1552483 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(1551923..1552483) Streptococcus thermophilus LMG 18311 3163904 YP_140155.1 CDS comEB NC_006448.1 1552596 1553066 R late competence protein required for DNA binding and uptake complement(1552596..1553066) Streptococcus thermophilus LMG 18311 3163958 YP_140156.1 CDS pepP NC_006448.1 1553070 1554131 R aminopeptidase complement(1553070..1554131) Streptococcus thermophilus LMG 18311 3164498 YP_140157.1 CDS stu1743 NC_006448.1 1554321 1554749 R hypothetical protein complement(1554321..1554749) Streptococcus thermophilus LMG 18311 3165567 YP_140158.1 CDS stu1744 NC_006448.1 1554794 1555225 R truncated; ABC transporter ATP binding protein, truncated complement(1554794..1555225) Streptococcus thermophilus LMG 18311 3165170 YP_140159.1 CDS stu1745 NC_006448.1 1555357 1555593 R truncated; ABC transporter ATP binding protein, truncated complement(1555357..1555593) Streptococcus thermophilus LMG 18311 3164585 YP_140160.1 CDS stu1746 NC_006448.1 1555933 1556124 R hypothetical protein complement(1555933..1556124) Streptococcus thermophilus LMG 18311 3164131 YP_140161.1 CDS stu1747 NC_006448.1 1556286 1556558 R hypothetical protein complement(1556286..1556558) Streptococcus thermophilus LMG 18311 3164673 YP_140162.1 CDS uvrA NC_006448.1 1556652 1559477 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1556652..1559477) Streptococcus thermophilus LMG 18311 3164445 YP_140163.1 CDS corA2 NC_006448.1 1559786 1560730 D magnesium/cobalt transporter CorA 1559786..1560730 Streptococcus thermophilus LMG 18311 3165135 YP_140164.1 CDS stu1750 NC_006448.1 1560801 1561472 D hypothetical protein 1560801..1561472 Streptococcus thermophilus LMG 18311 3164513 YP_140165.1 CDS stu1751 NC_006448.1 1561589 1562470 D hypothetical protein 1561589..1562470 Streptococcus thermophilus LMG 18311 3163807 YP_140166.1 CDS rpsR NC_006448.1 1562597 1562836 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1562597..1562836) Streptococcus thermophilus LMG 18311 3164530 YP_140167.1 CDS ssbB NC_006448.1 1562878 1563396 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1562878..1563396) Streptococcus thermophilus LMG 18311 3163824 YP_140168.2 CDS rpsF NC_006448.1 1563408 1563698 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1563408..1563698) Streptococcus thermophilus LMG 18311 3164015 YP_140169.1 CDS stu1755 NC_006448.1 1563917 1564249 D hypothetical protein 1563917..1564249 Streptococcus thermophilus LMG 18311 3164857 YP_140170.1 CDS stu1756 NC_006448.1 1564287 1564871 D hypothetical protein 1564287..1564871 Streptococcus thermophilus LMG 18311 3164828 YP_140171.1 CDS mutY NC_006448.1 1565536 1566687 D A/G-specific adenine glycosylase 1565536..1566687 Streptococcus thermophilus LMG 18311 3163777 YP_140172.1 CDS stu1758 NC_006448.1 1567014 1567265 R hypothetical protein complement(1567014..1567265) Streptococcus thermophilus LMG 18311 3164106 YP_140173.1 CDS stu1759 NC_006448.1 1567368 1567580 R hypothetical protein complement(1567368..1567580) Streptococcus thermophilus LMG 18311 3164537 YP_140174.1 CDS stu1760 NC_006448.1 1567583 1567927 R hypothetical protein complement(1567583..1567927) Streptococcus thermophilus LMG 18311 3165082 YP_140175.1 CDS polA NC_006448.1 1568515 1571154 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1568515..1571154) Streptococcus thermophilus LMG 18311 3165002 YP_140176.1 CDS mutS2 NC_006448.1 1571361 1573712 D DNA mismatch repair protein 1571361..1573712 Streptococcus thermophilus LMG 18311 3165046 YP_140177.1 CDS stu1763 NC_006448.1 1573814 1574356 R hypothetical protein complement(1573814..1574356) Streptococcus thermophilus LMG 18311 3165163 YP_140178.1 CDS stu1764 NC_006448.1 1574353 1574670 R hypothetical protein complement(1574353..1574670) Streptococcus thermophilus LMG 18311 3165128 YP_140179.1 CDS rnhB NC_006448.1 1574984 1575874 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1574984..1575874 Streptococcus thermophilus LMG 18311 3163788 YP_140180.1 CDS sipA NC_006448.1 1575893 1576516 D signal peptidase I 1575893..1576516 Streptococcus thermophilus LMG 18311 3165578 YP_140181.1 CDS recD NC_006448.1 1576578 1579082 D exodeoxyribonuclease V 1576578..1579082 Streptococcus thermophilus LMG 18311 3164800 YP_140182.1 CDS stu1768 NC_006448.1 1579138 1579464 R hypothetical protein complement(1579138..1579464) Streptococcus thermophilus LMG 18311 3164976 YP_140183.1 CDS stu1769 NC_006448.1 1579451 1580149 R branched chain amino acid exporter (LIV-E) family protein complement(1579451..1580149) Streptococcus thermophilus LMG 18311 3163914 YP_140184.1 CDS gcp NC_006448.1 1580195 1581208 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(1580195..1581208) Streptococcus thermophilus LMG 18311 3164555 YP_140185.1 CDS rimI NC_006448.1 1581208 1581663 R ribosomal-protein-alanine acetyltransferase complement(1581208..1581663) Streptococcus thermophilus LMG 18311 3164761 YP_140186.1 CDS stu1772 NC_006448.1 1581623 1582384 R glycoprotein endopeptidase complement(1581623..1582384) Streptococcus thermophilus LMG 18311 3164360 YP_140187.1 CDS stu1773 NC_006448.1 1582573 1582803 D hypothetical protein 1582573..1582803 Streptococcus thermophilus LMG 18311 3164468 YP_140188.1 CDS stu1774 NC_006448.1 1582808 1584490 D metallo-beta-lactamase superfamily protein 1582808..1584490 Streptococcus thermophilus LMG 18311 3164251 YP_140189.1 CDS stu1775 NC_006448.1 1584726 1584905 R glucan-binding protein complement(1584726..1584905) Streptococcus thermophilus LMG 18311 3164746 YP_140190.1 CDS gnlA NC_006448.1 1585316 1586686 R glutamine synthetase complement(1585316..1586686) Streptococcus thermophilus LMG 18311 3164916 YP_140191.1 CDS gnlR NC_006448.1 1586708 1587082 R glutamine synthetase transcriptional regulatorMerR family complement(1586708..1587082) Streptococcus thermophilus LMG 18311 3165047 YP_140192.1 CDS stu1778 NC_006448.1 1587256 1587759 R hypothetical protein complement(1587256..1587759) Streptococcus thermophilus LMG 18311 3165124 YP_140193.1 CDS stu1779 NC_006448.1 1588004 1588141 D truncated; truncated IS1193 transposase 1588004..1588141 Streptococcus thermophilus LMG 18311 3163808 YP_140194.1 CDS stu1780 NC_006448.1 1588138 1588344 D truncated; truncated IS1193 transposase 1588138..1588344 Streptococcus thermophilus LMG 18311 3164359 YP_140195.1 CDS stu1781 NC_006448.1 1588642 1588812 D truncated; truncated IS1193 transposase 1588642..1588812 Streptococcus thermophilus LMG 18311 3164441 YP_140196.1 CDS pgk NC_006448.1 1588885 1590084 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1588885..1590084) Streptococcus thermophilus LMG 18311 3164736 YP_140197.1 CDS stu1783 NC_006448.1 1590337 1590585 R truncated; hypothetical protein complement(1590337..1590585) Streptococcus thermophilus LMG 18311 3164168 YP_140198.1 CDS stu1784 NC_006448.1 1590700 1590984 D truncated; hypothetical protein 1590700..1590984 Streptococcus thermophilus LMG 18311 3163790 YP_140199.1 CDS stu1785 NC_006448.1 1591047 1591235 D truncated; hypothetical protein 1591047..1591235 Streptococcus thermophilus LMG 18311 3164827 YP_140200.1 CDS stu1786 NC_006448.1 1591211 1591549 D truncated; hypothetical protein 1591211..1591549 Streptococcus thermophilus LMG 18311 3164888 YP_140201.1 CDS stu1787 NC_006448.1 1591563 1592051 D truncated; hypothetical protein 1591563..1592051 Streptococcus thermophilus LMG 18311 3164497 YP_140202.1 CDS gapA1 NC_006448.1 1592201 1593238 R catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase complement(1592201..1593238) Streptococcus thermophilus LMG 18311 3164958 YP_140203.1 CDS fus NC_006448.1 1593398 1595479 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1593398..1595479) Streptococcus thermophilus LMG 18311 3164343 YP_140204.1 CDS rpsG NC_006448.1 1595700 1596170 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1595700..1596170) Streptococcus thermophilus LMG 18311 3164156 YP_140205.1 CDS rpsL NC_006448.1 1596189 1596602 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1596189..1596602) Streptococcus thermophilus LMG 18311 3164722 YP_140206.1 CDS tnp1239 NC_006448.1 1596832 1597872 R IS1239 transposase complement(1596832..1597872) Streptococcus thermophilus LMG 18311 3163833 YP_140207.1 CDS purR NC_006448.1 1598064 1598888 R pur operon repressor complement(1598064..1598888) Streptococcus thermophilus LMG 18311 3164681 YP_140208.1 CDS cbf NC_006448.1 1598982 1599935 R CMP-binding factor complement(1598982..1599935) Streptococcus thermophilus LMG 18311 3163923 YP_140209.1 CDS stu1795 NC_006448.1 1599913 1601187 R hypothetical protein complement(1599913..1601187) Streptococcus thermophilus LMG 18311 3164028 YP_140210.1 CDS stu1796 NC_006448.1 1601189 1601821 R hypothetical protein complement(1601189..1601821) Streptococcus thermophilus LMG 18311 3164239 YP_140211.1 CDS rpe NC_006448.1 1601814 1602533 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1601814..1602533) Streptococcus thermophilus LMG 18311 3164862 YP_140212.1 CDS stu1798 NC_006448.1 1602481 1603353 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1602481..1603353) Streptococcus thermophilus LMG 18311 3165035 YP_140213.1 CDS ksgA NC_006448.1 1603610 1604482 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1603610..1604482) Streptococcus thermophilus LMG 18311 3164047 YP_140214.1 CDS stu1800 NC_006448.1 1604627 1605187 R topoisomerase/primase complement(1604627..1605187) Streptococcus thermophilus LMG 18311 3164311 YP_140215.1 CDS tatD NC_006448.1 1605180 1605956 R deoxyribonuclease complement(1605180..1605956) Streptococcus thermophilus LMG 18311 3164327 YP_140216.1 CDS stu1802 NC_006448.1 1606010 1606462 R hypothetical protein complement(1606010..1606462) Streptococcus thermophilus LMG 18311 3163845 YP_140217.1 CDS trxA1 NC_006448.1 1606501 1606815 R thioredoxin complement(1606501..1606815) Streptococcus thermophilus LMG 18311 3163813 YP_140218.1 CDS stu1804 NC_006448.1 1607011 1607793 D hypothetical protein 1607011..1607793 Streptococcus thermophilus LMG 18311 3164640 YP_140219.1 CDS bta NC_006448.1 1608254 1608589 R bacteriocin transport accessory protein complement(1608254..1608589) Streptococcus thermophilus LMG 18311 3164936 YP_140220.1 CDS tgt NC_006448.1 1614422 1615564 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1614422..1615564) Streptococcus thermophilus LMG 18311 3165034 YP_140221.1 CDS tnp657 NC_006448.1 1615817 1616290 R IS200 family transposase complement(1615817..1616290) Streptococcus thermophilus LMG 18311 3164728 YP_140222.1 CDS rpmH NC_006448.1 1616468 1616602 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1616468..1616602) Streptococcus thermophilus LMG 18311 3164347 YP_140223.1 CDS jag NC_006448.1 1617490 1618539 R DNA/RNA-binding protein complement(1617490..1618539) Streptococcus thermophilus LMG 18311 3164536 YP_140224.1 CDS stu1810 NC_006448.1 1618551 1619357 R cytochrome oxidase biogenesis (Oxa1) family protein, SpoIIIJ complement(1618551..1619357) Streptococcus thermophilus LMG 18311 3164283 YP_140225.1 CDS rnpA NC_006448.1 1619472 1619807 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(1619472..1619807) Streptococcus thermophilus LMG 18311 3165136 YP_140226.1 CDS argH NC_006448.1 1619892 1621367 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(1619892..1621367) Streptococcus thermophilus LMG 18311 3164735 YP_140227.2 CDS argG NC_006448.1 1621606 1622805 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(1621606..1622805) Streptococcus thermophilus LMG 18311 3164282 YP_140228.1 CDS gltX NC_006448.1 1623708 1625162 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1623708..1625162) Streptococcus thermophilus LMG 18311 3164094 YP_140229.1 CDS stu1815 NC_006448.1 1625503 1625976 R truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated complement(1625503..1625976) Streptococcus thermophilus LMG 18311 3164466 YP_140230.1 CDS stu1816 NC_006448.1 1625973 1626398 R truncated; oligopeptide ABC uptake transporter substrate-binding protein, truncated complement(1625973..1626398) Streptococcus thermophilus LMG 18311 3164216 YP_140231.2 CDS rplA NC_006448.1 1626490 1627179 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1626490..1627179) Streptococcus thermophilus LMG 18311 3165050 YP_140232.1 CDS rplK NC_006448.1 1627279 1627704 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1627279..1627704) Streptococcus thermophilus LMG 18311 3163783 YP_140233.1 CDS stu1819 NC_006448.1 1627876 1628229 D hypothetical protein 1627876..1628229 Streptococcus thermophilus LMG 18311 3164531 YP_140234.1 CDS stu1820 NC_006448.1 1628321 1628818 R hypothetical protein complement(1628321..1628818) Streptococcus thermophilus LMG 18311 3164334 YP_140235.1 CDS stu1821 NC_006448.1 1628986 1629186 R truncated; hypothetical protein complement(1628986..1629186) Streptococcus thermophilus LMG 18311 3164011 YP_140236.1 CDS stu1822 NC_006448.1 1629180 1629410 R truncated; hypothetical protein complement(1629180..1629410) Streptococcus thermophilus LMG 18311 3165174 YP_140237.1 CDS radA NC_006448.1 1629750 1630997 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(1629750..1630997) Streptococcus thermophilus LMG 18311 3165032 YP_140238.1 CDS dut NC_006448.1 1631289 1631735 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1631289..1631735) Streptococcus thermophilus LMG 18311 3163785 YP_140239.1 CDS stu1825 NC_006448.1 1631913 1632329 D truncated; oxidoreductase, truncated 1631913..1632329 Streptococcus thermophilus LMG 18311 3164526 YP_140240.1 CDS stu1826 NC_006448.1 1632326 1632544 D truncated; oxidoreductase, truncated 1632326..1632544 Streptococcus thermophilus LMG 18311 3164932 YP_140241.1 CDS stu1827 NC_006448.1 1632572 1632799 D truncated; oxidoreductase, truncated 1632572..1632799 Streptococcus thermophilus LMG 18311 3164298 YP_140242.1 CDS stu1828 NC_006448.1 1632823 1633542 D truncated; oxidoreductase, truncated 1632823..1633542 Streptococcus thermophilus LMG 18311 3165044 YP_140243.1 CDS stu1829 NC_006448.1 1633749 1633931 D truncated; formate/nitrite transporter family protein, truncated 1633749..1633931 Streptococcus thermophilus LMG 18311 3164257 YP_140244.1 CDS stu1830 NC_006448.1 1634019 1634450 D truncated; formate/nitrite transporter family protein, truncated 1634019..1634450 Streptococcus thermophilus LMG 18311 3165154 YP_140245.1 CDS stu1831 NC_006448.1 1634459 1634914 D hypothetical protein 1634459..1634914 Streptococcus thermophilus LMG 18311 3164946 YP_140246.2 CDS gpsA NC_006448.1 1635147 1636169 D NAD(P)+; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1635147..1636169 Streptococcus thermophilus LMG 18311 3164684 YP_140247.1 CDS galU NC_006448.1 1636188 1637102 D UDP-glucose pyrophosphorylase 1636188..1637102 Streptococcus thermophilus LMG 18311 3164821 YP_140248.1 CDS tnpSth1 NC_006448.1 1637165 1638034 R IS3 familytransposase orf2 complement(1637165..1638034) Streptococcus thermophilus LMG 18311 3164858 YP_140249.1 CDS tnpSth1 NC_006448.1 1638049 1638789 R IS3 familytransposase orf1 complement(1638049..1638789) Streptococcus thermophilus LMG 18311 3164614 YP_140250.1 CDS stu1836 NC_006448.1 1638835 1639509 R hypothetical protein complement(1638835..1639509) Streptococcus thermophilus LMG 18311 3164706 YP_140251.1 CDS stu1837 NC_006448.1 1639500 1640027 R hypothetical protein complement(1639500..1640027) Streptococcus thermophilus LMG 18311 3163877 YP_140252.1 CDS hipO3 NC_006448.1 1640096 1641229 R aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase complement(1640096..1641229) Streptococcus thermophilus LMG 18311 3164683 YP_140253.1 CDS dapD NC_006448.1 1641308 1642006 R 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(1641308..1642006) Streptococcus thermophilus LMG 18311 3164799 YP_140254.1 CDS stu1840 NC_006448.1 1642092 1642496 R truncated; hypothetical protein complement(1642092..1642496) Streptococcus thermophilus LMG 18311 3165121 YP_140255.1 CDS stu1841 NC_006448.1 1642490 1642861 R truncated; hypothetical protein complement(1642490..1642861) Streptococcus thermophilus LMG 18311 3165072 YP_140256.1 CDS rrmA NC_006448.1 1642961 1643794 R rRNA (guanine-N1-)-methyltransferase complement(1642961..1643794) Streptococcus thermophilus LMG 18311 3164323 YP_140257.1 CDS stu1843 NC_006448.1 1644163 1644330 D hypothetical protein 1644163..1644330 Streptococcus thermophilus LMG 18311 3164031 YP_140258.1 CDS stu1844 NC_006448.1 1644727 1645245 R cytidine/deoxycytidylate deaminase family protein complement(1644727..1645245) Streptococcus thermophilus LMG 18311 3163957 YP_140259.1 CDS ssbA NC_006448.1 1646005 1646397 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1646005..1646397) Streptococcus thermophilus LMG 18311 3163873 YP_140260.1 CDS stu1846 NC_006448.1 1646602 1646829 R transcriptional regulator complement(1646602..1646829) Streptococcus thermophilus LMG 18311 3164048 YP_140261.1 CDS stu1847 NC_006448.1 1646844 1647875 R hypothetical protein complement(1646844..1647875) Streptococcus thermophilus LMG 18311 3165074 YP_140262.1 CDS stu1848 NC_006448.1 1648013 1648636 R phenylalanyl-tRNA synthetase-like protein complement(1648013..1648636) Streptococcus thermophilus LMG 18311 3164112 YP_140263.1 CDS trxA2 NC_006448.1 1648646 1648960 R thioredoxin complement(1648646..1648960) Streptococcus thermophilus LMG 18311 3164959 YP_140264.1 CDS stu1850 NC_006448.1 1648957 1649250 R hypothetical protein complement(1648957..1649250) Streptococcus thermophilus LMG 18311 3164482 YP_140265.1 CDS pepA NC_006448.1 1649341 1650408 D glutamyl-aminopeptidase 1649341..1650408 Streptococcus thermophilus LMG 18311 3164288 YP_140266.1 CDS proC NC_006448.1 1650424 1651194 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1650424..1651194 Streptococcus thermophilus LMG 18311 3164788 YP_140267.1 CDS stu1853 NC_006448.1 1651224 1651886 R hypothetical protein complement(1651224..1651886) Streptococcus thermophilus LMG 18311 3164889 YP_140268.1 CDS stu1854 NC_006448.1 1652108 1652437 R hypothetical protein complement(1652108..1652437) Streptococcus thermophilus LMG 18311 3164153 YP_140269.1 CDS stu1855 NC_006448.1 1652511 1652990 R truncated; hypothetical protein complement(1652511..1652990) Streptococcus thermophilus LMG 18311 3164680 YP_140270.1 CDS stu1856 NC_006448.1 1653179 1653388 R transcriptional regulator complement(1653179..1653388) Streptococcus thermophilus LMG 18311 3163868 YP_140271.1 CDS ackA NC_006448.1 1653625 1654845 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1653625..1654845) Streptococcus thermophilus LMG 18311 3164098 YP_140272.1 CDS stu1858 NC_006448.1 1654874 1655830 R hypothetical protein complement(1654874..1655830) Streptococcus thermophilus LMG 18311 3164954 YP_140273.1 CDS stu1859 NC_006448.1 1655875 1656192 R hypothetical protein complement(1655875..1656192) Streptococcus thermophilus LMG 18311 3164380 YP_140274.1 CDS stu1860 NC_006448.1 1656170 1656631 R competence protein complement(1656170..1656631) Streptococcus thermophilus LMG 18311 3164059 YP_140275.1 CDS stu1861 NC_006448.1 1656591 1656884 R hypothetical protein complement(1656591..1656884) Streptococcus thermophilus LMG 18311 3163791 YP_140276.1 CDS comGD NC_006448.1 1656856 1657284 R competence protein complement(1656856..1657284) Streptococcus thermophilus LMG 18311 3165112 YP_140277.1 CDS comGC NC_006448.1 1657244 1657570 R late competence protein, exogenous DNA-binding protein complement(1657244..1657570) Streptococcus thermophilus LMG 18311 3165113 YP_140278.1 CDS comGB NC_006448.1 1657567 1658673 R late competence protein, ABC transporter subunit complement(1657567..1658673) Streptococcus thermophilus LMG 18311 3163968 YP_140279.1 CDS comGA NC_006448.1 1658549 1659490 R late competence protein, ABC transporter subunit complement(1658549..1659490) Streptococcus thermophilus LMG 18311 3165134 YP_140280.1 CDS stu1866 NC_006448.1 1659571 1659933 R hypothetical protein complement(1659571..1659933) Streptococcus thermophilus LMG 18311 3164324 YP_140281.1 CDS rpoC NC_006448.1 1660092 1663730 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1660092..1663730) Streptococcus thermophilus LMG 18311 3164467 YP_140282.1 CDS rpoB NC_006448.1 1663831 1667412 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1663831..1667412) Streptococcus thermophilus LMG 18311 3164337 YP_140283.1 CDS pbp1B NC_006448.1 1667774 1670197 R penicillin-binding protein 1B complement(1667774..1670197) Streptococcus thermophilus LMG 18311 3164638 YP_140284.1 CDS tyrS NC_006448.1 1670239 1671555 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1670239..1671555 Streptococcus thermophilus LMG 18311 3163872 YP_140285.1 CDS ilvC NC_006448.1 1671681 1672703 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(1671681..1672703) Streptococcus thermophilus LMG 18311 3164366 YP_140286.1 CDS ilvH NC_006448.1 1672779 1673255 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1672779..1673255) Streptococcus thermophilus LMG 18311 3164934 YP_140287.1 CDS ilvB NC_006448.1 1673248 1674966 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit complement(1673248..1674966) Streptococcus thermophilus LMG 18311 3164762 YP_140288.1 CDS stu1874 NC_006448.1 1675082 1676572 R truncated; dihydroxy-acid dehydratase, truncated complement(1675082..1676572) Streptococcus thermophilus LMG 18311 3163855 YP_140289.1 CDS stu1875 NC_006448.1 1676972 1678639 R hypothetical protein complement(1676972..1678639) Streptococcus thermophilus LMG 18311 3164559 YP_140290.1 CDS asp NC_006448.1 1678639 1679004 R alkaline-shock protein complement(1678639..1679004) Streptococcus thermophilus LMG 18311 3164417 YP_140291.1 CDS norN NC_006448.1 1679114 1680403 R MATE family drug:Na+ antiporter complement(1679114..1680403) Streptococcus thermophilus LMG 18311 3164798 YP_140292.1 CDS thrC NC_006448.1 1680461 1681945 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(1680461..1681945) Streptococcus thermophilus LMG 18311 3164476 YP_140293.1 CDS stu1879 NC_006448.1 1682624 1682941 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1682624..1682941) Streptococcus thermophilus LMG 18311 3165076 YP_140294.1 CDS stu1880 NC_006448.1 1682934 1683167 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1682934..1683167) Streptococcus thermophilus LMG 18311 3163842 YP_140295.1 CDS stu1881 NC_006448.1 1683151 1683597 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1683151..1683597) Streptococcus thermophilus LMG 18311 3164462 YP_140296.1 CDS stu1882 NC_006448.1 1683598 1684158 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1683598..1684158) Streptococcus thermophilus LMG 18311 3164571 YP_140297.1 CDS stu1883 NC_006448.1 1684155 1684427 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1684155..1684427) Streptococcus thermophilus LMG 18311 3164894 YP_140298.1 CDS stu1884 NC_006448.1 1684735 1685130 R truncated; alcohol-acetaldehyde dehydrogenase, truncated complement(1684735..1685130) Streptococcus thermophilus LMG 18311 3163760 YP_140299.1 CDS pepO NC_006448.1 1685269 1687164 R endopeptidase O complement(1685269..1687164) Streptococcus thermophilus LMG 18311 3163809 YP_140300.1 CDS stu1886 NC_006448.1 1687245 1687904 R truncated; trehalose-6-phosphate hydrolase, truncated complement(1687245..1687904) Streptococcus thermophilus LMG 18311 3164503 YP_140301.1 CDS stu1887 NC_006448.1 1687918 1688271 R truncated; trehalose-6-phosphate hydrolase, truncated complement(1687918..1688271) Streptococcus thermophilus LMG 18311 3163748 YP_140302.1 CDS stu1888 NC_006448.1 1688439 1688585 R truncated; trehalose-6-phosphate hydrolase, truncated complement(1688439..1688585) Streptococcus thermophilus LMG 18311 3164867 YP_140303.1 CDS stu1889 NC_006448.1 1688459 1688779 R truncated; trehalose PTS trehalose component IIBC, truncated complement(1688459..1688779) Streptococcus thermophilus LMG 18311 3163917 YP_140304.1 CDS stu1890 NC_006448.1 1688810 1689175 R truncated; trehalose PTS trehalose component IIBC, truncated complement(1688810..1689175) Streptococcus thermophilus LMG 18311 3164595 YP_140305.1 CDS stu1891 NC_006448.1 1689272 1689409 R truncated; trehalose PTS trehalose component IIBC, truncated complement(1689272..1689409) Streptococcus thermophilus LMG 18311 3164812 YP_140306.1 CDS stu1892 NC_006448.1 1689521 1689679 D truncated; trehalose operon transcriptional repressor 1689521..1689679 Streptococcus thermophilus LMG 18311 3165117 YP_140307.1 CDS stu1893 NC_006448.1 1689734 1690231 D truncated; trehalose operon transcriptional regulator truncated 1689734..1690231 Streptococcus thermophilus LMG 18311 3164675 YP_140308.1 CDS stu1894 NC_006448.1 1690287 1690850 R hypothetical protein complement(1690287..1690850) Streptococcus thermophilus LMG 18311 3164250 YP_140309.1 CDS stu1895 NC_006448.1 1690860 1691198 R hypothetical protein complement(1690860..1691198) Streptococcus thermophilus LMG 18311 3164695 YP_140310.1 CDS stu1896 NC_006448.1 1691231 1691587 R hypothetical protein complement(1691231..1691587) Streptococcus thermophilus LMG 18311 3164883 YP_140312.1 CDS stu1898 NC_006448.1 1692168 1692623 D truncated; hypothetical protein 1692168..1692623 Streptococcus thermophilus LMG 18311 3163892 YP_140313.1 CDS fba NC_006448.1 1692898 1693779 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(1692898..1693779) Streptococcus thermophilus LMG 18311 3163937 YP_140314.1 CDS stu1900 NC_006448.1 1694198 1694803 R truncated; glutamate--cysteine ligase, truncated complement(1694198..1694803) Streptococcus thermophilus LMG 18311 3165164 YP_140315.1 CDS stu1901 NC_006448.1 1694861 1695049 R truncated; glutamate--cysteine ligase, truncated complement(1694861..1695049) Streptococcus thermophilus LMG 18311 3163773 YP_140316.1 CDS stu1902 NC_006448.1 1695110 1695256 R truncated; glutamate--cysteine ligase, truncated complement(1695110..1695256) Streptococcus thermophilus LMG 18311 3164967 YP_140317.1 CDS stu1903 NC_006448.1 1695353 1695538 R truncated; glutamate--cysteine ligase, truncated complement(1695353..1695538) Streptococcus thermophilus LMG 18311 3164678 YP_140318.1 CDS stu1904 NC_006448.1 1695618 1695773 D truncated; hypothetical protein 1695618..1695773 Streptococcus thermophilus LMG 18311 3164784 YP_140319.1 CDS stu1905 NC_006448.1 1695965 1696420 D truncated; hypothetical protein 1695965..1696420 Streptococcus thermophilus LMG 18311 3163750 YP_140320.1 CDS rplQ NC_006448.1 1696835 1697221 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1696835..1697221) Streptococcus thermophilus LMG 18311 3163900 YP_140321.1 CDS rpoA NC_006448.1 1697239 1698177 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1697239..1698177) Streptococcus thermophilus LMG 18311 3163927 YP_140322.1 CDS rpsK NC_006448.1 1698226 1698609 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1698226..1698609) Streptococcus thermophilus LMG 18311 3164870 YP_140323.1 CDS rpsM NC_006448.1 1698637 1699002 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1698637..1699002) Streptococcus thermophilus LMG 18311 3164873 YP_140324.1 CDS rpmJ NC_006448.1 1699020 1699136 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(1699020..1699136) Streptococcus thermophilus LMG 18311 3163743 YP_140325.1 CDS infA NC_006448.1 1699162 1699380 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1699162..1699380) Streptococcus thermophilus LMG 18311 3164535 YP_140326.1 CDS adk NC_006448.1 1699498 1700154 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(1699498..1700154) Streptococcus thermophilus LMG 18311 3164234 YP_140327.1 CDS secY NC_006448.1 1700286 1701581 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1700286..1701581) Streptococcus thermophilus LMG 18311 3163910 YP_140328.2 CDS rplO NC_006448.1 1701598 1702038 R late assembly protein; 50S ribosomal protein L15 complement(1701598..1702038) Streptococcus thermophilus LMG 18311 3164654 YP_140329.1 CDS rpmD NC_006448.1 1702166 1702348 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(1702166..1702348) Streptococcus thermophilus LMG 18311 3164707 YP_140330.1 CDS rpsE NC_006448.1 1702363 1702857 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1702363..1702857) Streptococcus thermophilus LMG 18311 3165166 YP_140331.2 CDS rplR NC_006448.1 1702876 1703232 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1702876..1703232) Streptococcus thermophilus LMG 18311 3164091 YP_140332.1 CDS rplF NC_006448.1 1703322 1703858 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1703322..1703858) Streptococcus thermophilus LMG 18311 3164598 YP_140333.1 CDS rpsH NC_006448.1 1703985 1704383 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1703985..1704383) Streptococcus thermophilus LMG 18311 3164579 YP_140334.1 CDS rpsN NC_006448.1 1704506 1704691 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(1704506..1704691) Streptococcus thermophilus LMG 18311 3164315 YP_140335.1 CDS rplE NC_006448.1 1704709 1705251 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1704709..1705251) Streptococcus thermophilus LMG 18311 3165080 YP_140336.1 CDS rplX NC_006448.1 1705278 1705583 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1705278..1705583) Streptococcus thermophilus LMG 18311 3164971 YP_140337.1 CDS rplN NC_006448.1 1705664 1706032 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1705664..1706032) Streptococcus thermophilus LMG 18311 3164956 YP_140338.1 CDS rpsQ NC_006448.1 1706057 1706317 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1706057..1706317) Streptococcus thermophilus LMG 18311 3163789 YP_140339.1 CDS rpmC NC_006448.1 1706345 1706551 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1706345..1706551) Streptococcus thermophilus LMG 18311 3164166 YP_140340.1 CDS rplP NC_006448.1 1706561 1706974 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1706561..1706974) Streptococcus thermophilus LMG 18311 3163796 YP_140341.1 CDS rpsC NC_006448.1 1706978 1707631 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1706978..1707631) Streptococcus thermophilus LMG 18311 3164070 YP_140342.1 CDS rplV NC_006448.1 1707644 1707988 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1707644..1707988) Streptococcus thermophilus LMG 18311 3164781 YP_140343.1 CDS rpsS NC_006448.1 1708004 1708282 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1708004..1708282) Streptococcus thermophilus LMG 18311 3164232 YP_140344.1 CDS rplB NC_006448.1 1708376 1709209 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1708376..1709209) Streptococcus thermophilus LMG 18311 3163909 YP_140345.1 CDS rplW NC_006448.1 1709227 1709523 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1709227..1709523) Streptococcus thermophilus LMG 18311 3165115 YP_140346.1 CDS rplD NC_006448.1 1709523 1710146 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1709523..1710146) Streptococcus thermophilus LMG 18311 3163802 YP_140347.1 CDS rplC NC_006448.1 1710171 1710797 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1710171..1710797) Streptococcus thermophilus LMG 18311 3164301 YP_140348.1 CDS rpsJ NC_006448.1 1710914 1711222 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1710914..1711222) Streptococcus thermophilus LMG 18311 3164739 YP_140349.1 CDS ruvB NC_006448.1 1711466 1712467 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1711466..1712467) Streptococcus thermophilus LMG 18311 3163844 YP_140350.1 CDS stu1937 NC_006448.1 1712548 1714371 R hypothetical protein complement(1712548..1714371) Streptococcus thermophilus LMG 18311 3164658 YP_140351.1 CDS stu1938 NC_006448.1 1714368 1714778 R hypothetical protein complement(1714368..1714778) Streptococcus thermophilus LMG 18311 3165145 YP_140352.1 CDS stu1939 NC_006448.1 1714775 1715209 R protein-tyrosine-phosphatase complement(1714775..1715209) Streptococcus thermophilus LMG 18311 3164118 YP_140353.1 CDS purA NC_006448.1 1715491 1716783 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1715491..1716783) Streptococcus thermophilus LMG 18311 3164073 YP_140354.1 CDS flaR NC_006448.1 1717037 1717552 R topology modulation protein complement(1717037..1717552) Streptococcus thermophilus LMG 18311 3165005 YP_140355.1 CDS stu1942 NC_006448.1 1717892 1719097 D hypothetical protein 1717892..1719097 Streptococcus thermophilus LMG 18311 3164344 YP_140356.1 CDS tnp1191 NC_006448.1 1719293 1720501 R IS1191 transposase complement(1719293..1720501) Streptococcus thermophilus LMG 18311 3164373 YP_140357.1 CDS stu1947 NC_006448.1 1720872 1721765 D MutR family transcriptional regulator 1720872..1721765 Streptococcus thermophilus LMG 18311 3165186 YP_140358.1 CDS stu1948 NC_006448.1 1721850 1724009 D hypothetical protein 1721850..1724009 Streptococcus thermophilus LMG 18311 3165148 YP_140359.1 CDS stu1949 NC_006448.1 1724014 1725582 D micrococin J25 ABC exporter ATP binding/membrane protein 1724014..1725582 Streptococcus thermophilus LMG 18311 3164543 YP_140360.1 CDS stu1950 NC_006448.1 1726501 1727199 D truncated; MutR family transcriptional regulator, truncated 1726501..1727199 Streptococcus thermophilus LMG 18311 3165063 YP_140361.1 CDS stu1951 NC_006448.1 1727366 1728640 D hypothetical protein 1727366..1728640 Streptococcus thermophilus LMG 18311 3164121 YP_140362.1 CDS stu1952 NC_006448.1 1728633 1730174 D ABC exporter ATP binding/membrane-spanning protein 1728633..1730174 Streptococcus thermophilus LMG 18311 3164165 YP_140363.1 CDS rip NC_006448.1 1730568 1731545 D replication initiator protein 1730568..1731545 Streptococcus thermophilus LMG 18311 3165058 YP_140364.1 CDS stu1954 NC_006448.1 1731557 1731745 D hypothetical protein 1731557..1731745 Streptococcus thermophilus LMG 18311 3164813 YP_140365.1 CDS int NC_006448.1 1731747 1732886 D integrase/recombinase 1731747..1732886 Streptococcus thermophilus LMG 18311 3164092 YP_140366.1 CDS cshA NC_006448.1 1733329 1734597 R recombination factor protein RarA complement(1733329..1734597) Streptococcus thermophilus LMG 18311 3163798 YP_140367.1 CDS rpmB NC_006448.1 1734768 1734956 D required for 70S ribosome assembly; 50S ribosomal protein L28 1734768..1734956 Streptococcus thermophilus LMG 18311 3164785 YP_140368.1 CDS stu1959 NC_006448.1 1735083 1735349 D hypothetical protein 1735083..1735349 Streptococcus thermophilus LMG 18311 3164724 YP_140369.1 CDS stu1960 NC_006448.1 1735349 1735768 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1735349..1735768 Streptococcus thermophilus LMG 18311 3164179 YP_140370.1 CDS stu1961 NC_006448.1 1735847 1736182 D hypothetical protein 1735847..1736182 Streptococcus thermophilus LMG 18311 3165062 YP_140371.1 CDS stu1962 NC_006448.1 1736395 1738041 D hypothetical protein 1736395..1738041 Streptococcus thermophilus LMG 18311 3164508 YP_140372.1 CDS nrdD NC_006448.1 1738151 1740355 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1738151..1740355 Streptococcus thermophilus LMG 18311 3164442 YP_140373.1 CDS stu1964 NC_006448.1 1740457 1740588 D hypothetical protein 1740457..1740588 Streptococcus thermophilus LMG 18311 3164093 YP_140374.1 CDS stu1965 NC_006448.1 1740590 1741090 D acetyltransferase 1740590..1741090 Streptococcus thermophilus LMG 18311 3164039 YP_140375.1 CDS nrdG NC_006448.1 1741095 1741700 D anaerobic ribonucleotide reductase activator 1741095..1741700 Streptococcus thermophilus LMG 18311 3165001 YP_140376.1 CDS stu1967 NC_006448.1 1741722 1742489 R hypothetical protein complement(1741722..1742489) Streptococcus thermophilus LMG 18311 3164173 YP_140377.1 CDS stu1968 NC_006448.1 1742549 1743490 R hypothetical protein complement(1742549..1743490) Streptococcus thermophilus LMG 18311 3164284 YP_140378.1 CDS aspS NC_006448.1 1743483 1745234 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1743483..1745234) Streptococcus thermophilus LMG 18311 3164517 YP_140379.1 CDS stu1970 NC_006448.1 1745344 1745766 R hypothetical protein complement(1745344..1745766) Streptococcus thermophilus LMG 18311 3164819 YP_140380.1 CDS hisS NC_006448.1 1745774 1747054 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1745774..1747054) Streptococcus thermophilus LMG 18311 3163860 YP_140381.1 CDS stu1972 NC_006448.1 1747364 1748122 R truncated; hypothetical protein complement(1747364..1748122) Streptococcus thermophilus LMG 18311 3164965 YP_140382.1 CDS stu1973 NC_006448.1 1748270 1748497 R truncated; hypothetical protein complement(1748270..1748497) Streptococcus thermophilus LMG 18311 3164558 YP_140383.1 CDS rpmF NC_006448.1 1748727 1748909 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1748727..1748909 Streptococcus thermophilus LMG 18311 3164554 YP_140384.1 CDS rpmG NC_006448.1 1748925 1749074 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1748925..1749074 Streptococcus thermophilus LMG 18311 3164997 YP_140385.1 CDS stu1976 NC_006448.1 1749295 1749528 R hypothetical protein complement(1749295..1749528) Streptococcus thermophilus LMG 18311 3164465 YP_140386.1 CDS stu1977 NC_006448.1 1749528 1749782 R hypothetical protein complement(1749528..1749782) Streptococcus thermophilus LMG 18311 3163867 YP_140387.1 CDS stu1978 NC_006448.1 1749841 1750020 R truncated; hypothetical protein complement(1749841..1750020) Streptococcus thermophilus LMG 18311 3163838 YP_140388.1 CDS stu1979 NC_006448.1 1750408 1750722 R truncated; hypothetical protein complement(1750408..1750722) Streptococcus thermophilus LMG 18311 3164010 YP_140389.1 CDS stu1980 NC_006448.1 1751068 1751658 R truncated; hypothetical protein complement(1751068..1751658) Streptococcus thermophilus LMG 18311 3163876 YP_140390.1 CDS stu1981 NC_006448.1 1751714 1752085 R hypothetical protein complement(1751714..1752085) Streptococcus thermophilus LMG 18311 3164006 YP_140391.1 CDS stu1982 NC_006448.1 1752674 1752913 D hypothetical protein 1752674..1752913 Streptococcus thermophilus LMG 18311 3164749 YP_140392.1 CDS stu1983 NC_006448.1 1752972 1753538 D hypothetical protein 1752972..1753538 Streptococcus thermophilus LMG 18311 3164520 YP_140393.1 CDS stu1984 NC_006448.1 1753551 1753721 D hypothetical protein 1753551..1753721 Streptococcus thermophilus LMG 18311 3164911 YP_140394.1 CDS tnp1239 NC_006448.1 1753765 1754805 R IS1239 transposase complement(1753765..1754805) Streptococcus thermophilus LMG 18311 3163755 YP_140395.1 CDS stu1986 NC_006448.1 1754980 1755537 D hypothetical protein 1754980..1755537 Streptococcus thermophilus LMG 18311 3163903 YP_140396.1 CDS stu1987 NC_006448.1 1755610 1755813 D hypothetical protein 1755610..1755813 Streptococcus thermophilus LMG 18311 3164005 YP_140397.1 CDS stu1988 NC_006448.1 1756405 1756956 R hypothetical protein complement(1756405..1756956) Streptococcus thermophilus LMG 18311 3164576 YP_140398.1 CDS stu1989 NC_006448.1 1757243 1757395 D truncated; hypothetical protein 1757243..1757395 Streptococcus thermophilus LMG 18311 3164494 YP_140399.1 CDS stu1990 NC_006448.1 1757409 1757570 D truncated; hypothetical protein 1757409..1757570 Streptococcus thermophilus LMG 18311 3163837 YP_140400.1 CDS stu1991 NC_006448.1 1757776 1757997 D hypothetical protein 1757776..1757997 Streptococcus thermophilus LMG 18311 3164363 YP_140401.1 CDS stu1992 NC_006448.1 1758111 1758986 D hypothetical protein 1758111..1758986 Streptococcus thermophilus LMG 18311 3165195 YP_140402.1 CDS stu1993 NC_006448.1 1759023 1761155 R truncated; hypothetical protein complement(1759023..1761155) Streptococcus thermophilus LMG 18311 3164181 YP_140403.1 CDS stu1994 NC_006448.1 1761133 1761393 R truncated; hypothetical protein complement(1761133..1761393) Streptococcus thermophilus LMG 18311 3163994 YP_140404.1 CDS stu1995 NC_006448.1 1761522 1762061 D TetR/AcrR family transcriptional regulator 1761522..1762061 Streptococcus thermophilus LMG 18311 3163803 YP_140405.1 CDS stu1996 NC_006448.1 1762139 1762501 R hypothetical protein complement(1762139..1762501) Streptococcus thermophilus LMG 18311 3164123 YP_140406.1 CDS rpsD NC_006448.1 1763032 1763685 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1763032..1763685) Streptococcus thermophilus LMG 18311 3164407 YP_140407.1 CDS stu1998 NC_006448.1 1763841 1764143 R hypothetical protein complement(1763841..1764143) Streptococcus thermophilus LMG 18311 3164522 YP_140408.1 CDS holB NC_006448.1 1764167 1765528 R unwinds double stranded DNA; replicative DNA helicase complement(1764167..1765528) Streptococcus thermophilus LMG 18311 3163995 YP_140409.2 CDS rplI NC_006448.1 1765572 1766030 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1765572..1766030) Streptococcus thermophilus LMG 18311 3164697 YP_140410.1 CDS stu2001 NC_006448.1 1766032 1767996 R hypothetical protein complement(1766032..1767996) Streptococcus thermophilus LMG 18311 3163959 YP_140411.1 CDS gidA NC_006448.1 1768070 1770073 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(1768070..1770073) Streptococcus thermophilus LMG 18311 3164766 YP_140412.1 CDS mnmA NC_006448.1 1770246 1771367 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1770246..1771367) Streptococcus thermophilus LMG 18311 3164493 YP_140413.1 CDS stu2004 NC_006448.1 1771506 1773236 R hypothetical protein complement(1771506..1773236) Streptococcus thermophilus LMG 18311 3165092 YP_140414.1 CDS stu2005 NC_006448.1 1773323 1773952 R hypothetical protein complement(1773323..1773952) Streptococcus thermophilus LMG 18311 3164489 YP_140415.1 CDS stu2006 NC_006448.1 1774193 1774747 R hypothetical protein complement(1774193..1774747) Streptococcus thermophilus LMG 18311 3165083 YP_140416.1 CDS stu2007 NC_006448.1 1775051 1775845 R ABC transporter membrane-spanning protein complement(1775051..1775845) Streptococcus thermophilus LMG 18311 3164778 YP_140417.1 CDS cbiO NC_006448.1 1775838 1776680 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(1775838..1776680) Streptococcus thermophilus LMG 18311 3164807 YP_140418.1 CDS cbiO NC_006448.1 1776656 1777486 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(1776656..1777486) Streptococcus thermophilus LMG 18311 3164453 YP_140419.1 CDS pgsA NC_006448.1 1777499 1778041 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1777499..1778041) Streptococcus thermophilus LMG 18311 3164538 YP_140420.1 CDS stu2011 NC_006448.1 1778054 1778911 R hypothetical protein complement(1778054..1778911) Streptococcus thermophilus LMG 18311 3164083 YP_140421.1 CDS stu2012 NC_006448.1 1778970 1780247 R peptidase complement(1778970..1780247) Streptococcus thermophilus LMG 18311 3164253 YP_140422.1 CDS stu2013 NC_006448.1 1780249 1781499 R protease complement(1780249..1781499) Streptococcus thermophilus LMG 18311 3165588 YP_140423.1 CDS stu2014 NC_006448.1 1781577 1781954 D hypothetical protein 1781577..1781954 Streptococcus thermophilus LMG 18311 3163990 YP_140424.1 CDS recF NC_006448.1 1781957 1783057 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1781957..1783057 Streptococcus thermophilus LMG 18311 3164279 YP_140425.1 CDS guaB NC_006448.1 1783226 1784707 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(1783226..1784707) Streptococcus thermophilus LMG 18311 3165149 YP_140426.1 CDS tnp1239 NC_006448.1 1785019 1786059 D IS1239 transposase 1785019..1786059 Streptococcus thermophilus LMG 18311 3164688 YP_140427.1 CDS trpS NC_006448.1 1786129 1787151 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1786129..1787151) Streptococcus thermophilus LMG 18311 3165438 YP_140428.1 CDS stu2019 NC_006448.1 1788017 1788451 D truncated; hypothetical protein 1788017..1788451 Streptococcus thermophilus LMG 18311 3164362 YP_140429.1 CDS stu2020 NC_006448.1 1788518 1790140 D ABC transporter ATP-binding protein 1788518..1790140 Streptococcus thermophilus LMG 18311 3164080 YP_140430.1 CDS stu2021 NC_006448.1 1790190 1792796 D ABC transporter membrane-spanning protein 1790190..1792796 Streptococcus thermophilus LMG 18311 3164519 YP_140431.1 CDS stu2022 NC_006448.1 1793341 1794024 R hypothetical protein complement(1793341..1794024) Streptococcus thermophilus LMG 18311 3163793 YP_140432.2 CDS stu2023 NC_006448.1 1794040 1794519 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(1794040..1794519) Streptococcus thermophilus LMG 18311 3164694 YP_140433.1 CDS htrA NC_006448.1 1794724 1795959 D exported serine protease 1794724..1795959 Streptococcus thermophilus LMG 18311 3165096 YP_140434.1 CDS spoJ NC_006448.1 1796025 1796792 D chromosome segregation protein 1796025..1796792 Streptococcus thermophilus LMG 18311 3163797 stu_t01 tRNA stu_t01 NC_006448.1 19420 19492 D tRNA-Ala 19420..19492 Streptococcus thermophilus LMG 18311 3370950 stu_t02 tRNA stu_t02 NC_006448.1 22744 22816 D tRNA-Val 22744..22816 Streptococcus thermophilus LMG 18311 3370951 stu_t03 tRNA stu_t03 NC_006448.1 22819 22891 D tRNA-Asp 22819..22891 Streptococcus thermophilus LMG 18311 3370979 stu_t04 tRNA stu_t04 NC_006448.1 22911 22983 D tRNA-Lys 22911..22983 Streptococcus thermophilus LMG 18311 3370980 stu_t05 tRNA stu_t05 NC_006448.1 22989 23070 D tRNA-Leu 22989..23070 Streptococcus thermophilus LMG 18311 3370981 stu_t06 tRNA stu_t06 NC_006448.1 23085 23157 D tRNA-Thr 23085..23157 Streptococcus thermophilus LMG 18311 3370982 stu_t07 tRNA stu_t07 NC_006448.1 23164 23235 D tRNA-Gly 23164..23235 Streptococcus thermophilus LMG 18311 3370983 stu_t08 tRNA stu_t08 NC_006448.1 23242 23327 D tRNA-Leu 23242..23327 Streptococcus thermophilus LMG 18311 3370984 stu_t09 tRNA stu_t09 NC_006448.1 23342 23415 D tRNA-Arg 23342..23415 Streptococcus thermophilus LMG 18311 3370985 stu_t10 tRNA stu_t10 NC_006448.1 23423 23496 D tRNA-Pro 23423..23496 Streptococcus thermophilus LMG 18311 3370986 stu_t11 tRNA stu_t11 NC_006448.1 23502 23575 D tRNA-Met 23502..23575 Streptococcus thermophilus LMG 18311 3370987 stu_t12 tRNA stu_t12 NC_006448.1 23590 23663 D tRNA-Met 23590..23663 Streptococcus thermophilus LMG 18311 3370997 stu_t13 tRNA stu_t13 NC_006448.1 23683 23772 D tRNA-OTHER 23683..23772 Streptococcus thermophilus LMG 18311 3370998 stu_t14 tRNA stu_t14 NC_006448.1 23782 23855 D tRNA-Met 23782..23855 Streptococcus thermophilus LMG 18311 3370999 stu_t15 tRNA stu_t15 NC_006448.1 23859 23931 D tRNA-Phe 23859..23931 Streptococcus thermophilus LMG 18311 3371000 stu_t16 tRNA stu_t16 NC_006448.1 23944 24014 D tRNA-Gly 23944..24014 Streptococcus thermophilus LMG 18311 3371001 stu_t17 tRNA stu_t17 NC_006448.1 24048 24121 D tRNA-Ile 24048..24121 Streptococcus thermophilus LMG 18311 3371002 stu_t18 tRNA stu_t18 NC_006448.1 24126 24213 D tRNA-OTHER 24126..24213 Streptococcus thermophilus LMG 18311 3371003 stu_t19 tRNA stu_t19 NC_006448.1 68401 68473 D tRNA-Ala 68401..68473 Streptococcus thermophilus LMG 18311 3371004 stu_t20 tRNA stu_t20 NC_006448.1 71725 71797 D tRNA-Val 71725..71797 Streptococcus thermophilus LMG 18311 3371005 stu_t21 tRNA stu_t21 NC_006448.1 71802 71872 D tRNA-Gly 71802..71872 Streptococcus thermophilus LMG 18311 3370952 stu_t22 tRNA stu_t22 NC_006448.1 71906 71979 D tRNA-Ile 71906..71979 Streptococcus thermophilus LMG 18311 3370953 stu_t23 tRNA stu_t23 NC_006448.1 71986 72057 D tRNA-Glu 71986..72057 Streptococcus thermophilus LMG 18311 3370954 stu_t24 tRNA stu_t24 NC_006448.1 72066 72155 D tRNA-OTHER 72066..72155 Streptococcus thermophilus LMG 18311 3370955 stu_t25 tRNA stu_t25 NC_006448.1 72165 72238 D tRNA-Met 72165..72238 Streptococcus thermophilus LMG 18311 3370956 stu_t26 tRNA stu_t26 NC_006448.1 72242 72314 D tRNA-Phe 72242..72314 Streptococcus thermophilus LMG 18311 3370957 stu_t27 tRNA stu_t27 NC_006448.1 72329 72409 D tRNA-Tyr 72329..72409 Streptococcus thermophilus LMG 18311 3370958 stu_t28 tRNA stu_t28 NC_006448.1 72415 72485 D tRNA-Trp 72415..72485 Streptococcus thermophilus LMG 18311 3370959 stu_t29 tRNA stu_t29 NC_006448.1 72497 72569 D tRNA-His 72497..72569 Streptococcus thermophilus LMG 18311 3370960 stu_t30 tRNA stu_t30 NC_006448.1 72576 72647 D tRNA-Gln 72576..72647 Streptococcus thermophilus LMG 18311 3370961 stu_t31 tRNA stu_t31 NC_006448.1 72657 72740 D tRNA-Leu 72657..72740 Streptococcus thermophilus LMG 18311 3370988 stu_t32 tRNA stu_t32 NC_006448.1 82562 82632 D tRNA-Cys 82562..82632 Streptococcus thermophilus LMG 18311 3370989 stu_t33 tRNA stu_t33 NC_006448.1 130645 130717 D tRNA-Ala 130645..130717 Streptococcus thermophilus LMG 18311 3370990 stu_t34 tRNA stu_t34 NC_006448.1 133969 134041 D tRNA-Val 133969..134041 Streptococcus thermophilus LMG 18311 3370991 stu_t35 tRNA stu_t35 NC_006448.1 134044 134116 D tRNA-Asp 134044..134116 Streptococcus thermophilus LMG 18311 3370992 stu_t36 tRNA stu_t36 NC_006448.1 134136 134208 D tRNA-Lys 134136..134208 Streptococcus thermophilus LMG 18311 3370993 stu_t37 tRNA stu_t37 NC_006448.1 134214 134295 D tRNA-Leu 134214..134295 Streptococcus thermophilus LMG 18311 3370994 stu_t38 tRNA stu_t38 NC_006448.1 134310 134382 D tRNA-Thr 134310..134382 Streptococcus thermophilus LMG 18311 3370995 stu_t39 tRNA stu_t39 NC_006448.1 134389 134460 D tRNA-Gly 134389..134460 Streptococcus thermophilus LMG 18311 3370996 stu_t40 tRNA stu_t40 NC_006448.1 134467 134552 D tRNA-Leu 134467..134552 Streptococcus thermophilus LMG 18311 3370962 stu_t41 tRNA stu_t41 NC_006448.1 134567 134640 D tRNA-Arg 134567..134640 Streptococcus thermophilus LMG 18311 3370963 stu_t42 tRNA stu_t42 NC_006448.1 134648 134721 D tRNA-Pro 134648..134721 Streptococcus thermophilus LMG 18311 3370964 stu_t43 tRNA stu_t43 NC_006448.1 136452 136524 D tRNA-Ala 136452..136524 Streptococcus thermophilus LMG 18311 3370965 stu_t44 tRNA stu_t44 NC_006448.1 139776 139849 D tRNA-Asn 139776..139849 Streptococcus thermophilus LMG 18311 3370966 stu_t45 tRNA stu_t45 NC_006448.1 359975 360047 D tRNA-Ala 359975..360047 Streptococcus thermophilus LMG 18311 3370967 stu_t46 tRNA stu_t46 NC_006448.1 363299 363371 D tRNA-Val 363299..363371 Streptococcus thermophilus LMG 18311 3370968 stu_t47 tRNA stu_t47 NC_006448.1 363374 363446 D tRNA-Asp 363374..363446 Streptococcus thermophilus LMG 18311 3370969 stu_t48 tRNA stu_t48 NC_006448.1 363466 363538 D tRNA-Lys 363466..363538 Streptococcus thermophilus LMG 18311 3370970 stu_t49 tRNA stu_t49 NC_006448.1 363544 363625 D tRNA-Leu 363544..363625 Streptococcus thermophilus LMG 18311 3370931 stu_t50 tRNA stu_t50 NC_006448.1 363640 363712 D tRNA-Thr 363640..363712 Streptococcus thermophilus LMG 18311 3370932 stu_t51 tRNA stu_t51 NC_006448.1 363720 363791 D tRNA-Glu 363720..363791 Streptococcus thermophilus LMG 18311 3370933 stu_t52 tRNA stu_t52 NC_006448.1 563203 563283 D tRNA-Tyr 563203..563283 Streptococcus thermophilus LMG 18311 3370934 stu_t53 tRNA stu_t53 NC_006448.1 563352 563423 D tRNA-Gln 563352..563423 Streptococcus thermophilus LMG 18311 3370935 stu_t54 tRNA stu_t54 NC_006448.1 564815 564886 D tRNA-Arg 564815..564886 Streptococcus thermophilus LMG 18311 3370936 stu_t55 tRNA stu_t55 NC_006448.1 1036343 1036414 R tRNA-Arg complement(1036343..1036414) Streptococcus thermophilus LMG 18311 3370949 stu_t56 tRNA stu_t56 NC_006448.1 1254121 1254192 R tRNA-Glu complement(1254121..1254192) Streptococcus thermophilus LMG 18311 3370948 stu_t57 tRNA stu_t57 NC_006448.1 1254222 1254293 R tRNA-Gln complement(1254222..1254293) Streptococcus thermophilus LMG 18311 3370947 stu_t58 tRNA stu_t58 NC_006448.1 1345552 1345622 R tRNA-Thr complement(1345552..1345622) Streptococcus thermophilus LMG 18311 3370946 stu_t59 tRNA stu_t59 NC_006448.1 1423092 1423178 R tRNA-Ser complement(1423092..1423178) Streptococcus thermophilus LMG 18311 3370945 stu_t60 tRNA stu_t60 NC_006448.1 1603489 1603571 D tRNA-Leu 1603489..1603571 Streptococcus thermophilus LMG 18311 3370937 stu_t61 tRNA stu_t61 NC_006448.1 1608696 1608769 R tRNA-Asn complement(1608696..1608769) Streptococcus thermophilus LMG 18311 3370944 stu_t62 tRNA stu_t62 NC_006448.1 1612026 1612098 R tRNA-Ala complement(1612026..1612098) Streptococcus thermophilus LMG 18311 3370943 stu_t63 tRNA stu_t63 NC_006448.1 1693928 1694013 R tRNA-Leu complement(1693928..1694013) Streptococcus thermophilus LMG 18311 3370942 stu_t64 tRNA stu_t64 NC_006448.1 1732973 1733045 R tRNA-Lys complement(1732973..1733045) Streptococcus thermophilus LMG 18311 3370941 stu_t65 tRNA stu_t65 NC_006448.1 1792886 1792959 R tRNA-Asn complement(1792886..1792959) Streptococcus thermophilus LMG 18311 3370940 stu_t66 tRNA stu_t66 NC_006448.1 1792982 1793053 R tRNA-Glu complement(1792982..1793053) Streptococcus thermophilus LMG 18311 3370939 stu_t67 tRNA stu_t67 NC_006448.1 1793242 1793315 D tRNA-Arg 1793242..1793315 Streptococcus thermophilus LMG 18311 3370938 stu_r01 rRNA stu_r01 NC_006448.1 17819 19373 D 16S ribosomal RNA 17819..19373 Streptococcus thermophilus LMG 18311 3370927 stu_r02 rRNA stu_r02 NC_006448.1 19639 22539 D 23S ribosomal RNA 19639..22539 Streptococcus thermophilus LMG 18311 3370973 stu_r03 rRNA stu_r03 NC_006448.1 22616 22741 D 5S ribosomal RNA 22616..22741 Streptococcus thermophilus LMG 18311 3370921 stu_r04 rRNA stu_r04 NC_006448.1 66800 68354 D 16S ribosomal RNA 66800..68354 Streptococcus thermophilus LMG 18311 3370928 stu_r05 rRNA stu_r05 NC_006448.1 68620 71520 D 23S ribosomal RNA 68620..71520 Streptococcus thermophilus LMG 18311 3370974 stu_r06 rRNA stu_r06 NC_006448.1 71597 71722 D 5S ribosomal RNA 71597..71722 Streptococcus thermophilus LMG 18311 3370922 stu_r07 rRNA stu_r07 NC_006448.1 129044 130598 D 16S ribosomal RNA 129044..130598 Streptococcus thermophilus LMG 18311 3370929 stu_r08 rRNA stu_r08 NC_006448.1 130864 133764 D 23S ribosomal RNA 130864..133764 Streptococcus thermophilus LMG 18311 3370975 stu_r09 rRNA stu_r09 NC_006448.1 133841 133966 D 5S ribosomal RNA 133841..133966 Streptococcus thermophilus LMG 18311 3370923 stu_r10 rRNA stu_r10 NC_006448.1 134851 136405 D 16S ribosomal RNA 134851..136405 Streptococcus thermophilus LMG 18311 3370930 stu_r11 rRNA stu_r11 NC_006448.1 136671 139571 D 23S ribosomal RNA 136671..139571 Streptococcus thermophilus LMG 18311 3370976 stu_r12 rRNA stu_r12 NC_006448.1 139648 139770 D 5S ribosomal RNA 139648..139770 Streptococcus thermophilus LMG 18311 3370924 stu_r13 rRNA stu_r13 NC_006448.1 358374 359928 D 16S ribosomal RNA 358374..359928 Streptococcus thermophilus LMG 18311 3370971 stu_r14 rRNA stu_r14 NC_006448.1 360194 363094 D 23S ribosomal RNA 360194..363094 Streptococcus thermophilus LMG 18311 3370977 stu_r15 rRNA stu_r15 NC_006448.1 363171 363296 D 5S ribosomal RNA 363171..363296 Streptococcus thermophilus LMG 18311 3370925 stu_r16 rRNA stu_r16 NC_006448.1 1608775 1608897 R 5S ribosomal RNA complement(1608775..1608897) Streptococcus thermophilus LMG 18311 3370926 stu_r17 rRNA stu_r17 NC_006448.1 1608974 1611879 R 23S ribosomal RNA complement(1608974..1611879) Streptococcus thermophilus LMG 18311 3370978 stu_r18 rRNA stu_r18 NC_006448.1 1612145 1613699 R 16S ribosomal RNA complement(1612145..1613699) Streptococcus thermophilus LMG 18311 3370972