-- dump date 20111121_015152 -- class Genbank::CDS -- table cds_note -- id note NP_821176.1 PF04851: Type III restriction enzyme, res subunit NP_821179.1 PF07336: Protein of unknown function (DUF1470) NP_821181.1 PF00589: Phage integrase family NP_821185.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_821186.1 PF00805: Pentapeptide repeats (8 copies) NP_821187.1 PF03457: Helicase associated domain NP_821195.1 PF05593: RHS Repeat NP_821205.1 PF01569: PAP2 superfamily NP_821212.1 PF00561: alpha/beta hydrolase fold NP_821213.1 probably pseudogene NP_821217.1 Tn5741 family, partial NP_821218.1 PF07470: Glycosyl Hydrolase Family 88 NP_821220.1 IS5 family NP_821221.1 IS200/IS605 family NP_821225.1 PF00583: Acetyltransferase (GNAT) family NP_821231.1 PF01833: IPT/TIG domain NP_821232.1 PF01833: IPT/TIG domain NP_821235.1 IS200/IS605 family NP_821240.1 IS200/IS605 family, truncated NP_821241.1 PF00165: Bacterial regulatory helix-turn-helix proteins, araC family NP_821245.1 PF03364: Streptomyces cyclase/dehydrase NP_821249.1 PF01042: Endoribonuclease L-PSP NP_821250.1 terpene biosynthesis NP_821251.1 truncated methyltransferase NP_821254.1 mycinamicin resistance protein homolog NP_821255.1 PF01522: Polysaccharide deacetylase NP_821258.1 PF05139: Erythromycin esterase NP_821260.1 LuxR-family transcriptional regulatory protein NP_821262.1 PF00125: Core histone H2A/H2B/H3/H4 NP_821263.1 PF03752: Short repeats of unknown function NP_821266.1 PF04203: Sortase family NP_821272.1 PF00723: Glycosyl hydrolases family 15 NP_821273.1 PF03176: MMPL family NP_821274.1 pks11 NP_821275.1 pks11 containing aminotransferase domain NP_821278.1 IS256 family, partial NP_821283.1 CYP154A2 NP_821284.1 IS112 homolog NP_821286.1 PF01590: GAF domain NP_821289.1 IS6 family NP_821297.1 PF01135: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NP_821299.1 PF00597: DedA family NP_821300.1 PF01569: PAP2 superfamily NP_821301.1 PF01569: PAP2 superfamily NP_821304.1 PF03988: Repeat of Unknown Function (DUF347) NP_821305.1 PF03988: Repeat of Unknown Function (DUF347) NP_821312.1 PF02687: Predicted permease NP_821315.1 PF00561: alpha/beta hydrolase fold NP_821316.1 PF00106: short chain dehydrogenase NP_821318.1 PF01061: ABC-2 type transporter NP_821319.1 PF03176: MMPL family NP_821322.1 PF03022: Major royal jelly protein NP_821324.1 PF00106: short chain dehydrogenase NP_821326.1 PF00106: short chain dehydrogenase NP_821328.1 PF00561: alpha/beta hydrolase fold NP_821330.1 PF00111: 2Fe-2S iron-sulfur cluster binding domain NP_821331.1 PF06827: Zinc finger found in FPG and IleRS NP_821333.1 PF00589: Phage integrase family NP_821343.1 PF00583: Acetyltransferase (GNAT) family NP_821351.1 PF01970: Integral membrane protein DUF112 NP_821352.1 Seems to have a cleavable N-term signal sequence NP_821359.1 PF00437: Type II/IV secretion system protein NP_821360.1 PF00482: Bacterial type II secretion system protein F domain NP_821361.1 PF00482: Bacterial type II secretion system protein F domain NP_821366.1 PF01476: LysM domain NP_821368.1 PF00583: Acetyltransferase (GNAT) family NP_821369.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_821370.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_821374.1 PF05593: RHS Repeat NP_821380.1 Tn4561 family, truncated NP_821381.1 truncated NP_821387.1 probably pseudogene NP_821389.1 PF05729: NACHT domain NP_821390.1 PF03819: MazG nucleotide pyrophosphohydrolase domain NP_821391.1 PF00550: Phosphopantetheine attachment site NP_821393.1 PF06114 :Domain of unknown function (DUF955) NP_821397.1 PF03457: Helicase associated domain NP_821400.1 PF00078: Reverse transcriptase (RNA-dependent DNA polymerase) NP_821401.1 similar to IS 4-family transposase NP_821404.1 PF05935: Arylsulfotransferase (ASST) NP_821408.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_821409.1 PF01740: STAS domain NP_821415.1 PF03869: Arc-like DNA binding domain NP_821419.1 PF01810: LysE type translocator NP_821421.1 PF05729: NACHT domain NP_821424.1 PF00515: TPR Domain NP_821425.1 PF02355: Protein export membrane protein NP_821428.1 Tn5741 family, truncated NP_821429.1 PF01433: Peptidase family M1 NP_821430.1 PF01609: Transposase DDE domain NP_821449.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_821453.1 PF02945: Recombination endonuclease VII NP_821460.1 PF05593: RHS Repeat NP_821461.1 IS630 family NP_821465.1 IS30 family NP_821467.1 PF00175: Oxidoreductase NAD-binding domain NP_821470.1 PF01360: Monooxygenase NP_821471.1 PF00561: alpha/beta hydrolase fold NP_821472.1 PF00561: alpha/beta hydrolase fold NP_821475.1 PF01609: Transposase DDE domain NP_821477.1 IS116/IS110/IS902 family NP_821482.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821483.1 PF07592: Rhodopirellula transposase NP_821485.1 IS4 family, partial NP_821490.3 IS5 family, frame shift NP_821491.1 IS5 family NP_821492.2 IS5 family NP_821495.1 PF01590: GAF domain NP_821496.1 PF03006: Haemolysin-III related NP_821500.1 PF03819: MazG nucleotide pyrophosphohydrolase domain NP_821513.1 PF00056: lactate/malate dehydrogenase, NAD binding domain NP_821517.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_821518.1 PF06054: Competence protein CoiA-like family NP_821524.1 PF01590: GAF domain NP_821529.1 PF00534: Glycosyl transferases group 1 NP_821538.1 IS116/IS110/IS902 family NP_821542.1 PF04434: SWIM zinc finger NP_821544.1 PF00589: Phage integrase family NP_821545.1 PF03807: NADP oxidoreductase coenzyme F420-dependent NP_821546.1 PF00459: Inositol monophosphatase family NP_821549.1 IS200/IS605 family NP_821550.1 PF02954: Bacterial regulatory protein, Fis family NP_821551.1 PF00501: AMP-binding enzyme NP_821552.1 Tn5741 family, truncated NP_821555.1 PF04984: Phage tail sheath protein NP_821561.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_821567.1 PF04965: GPW / gp25 family NP_821574.1 PF03704: Bacterial transcriptional activator domain NP_821578.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm NP_821579.1 PF00583: Acetyltransferase (GNAT) family NP_821580.1 PF00293: NUDIX domain NP_821582.1 filipin gene cluster NP_821583.1 filipin gene cluster, PF05199: GMC oxidoreductase NP_821584.1 filipin gene cluster NP_821585.1 filipin gene cluster, PF06498: Adenylate cyclase associated, PF03704: Bacterial transcriptional activator domain NP_821586.1 fdxI, filipin gene cluster NP_821587.1 CYP105D6, fdxI is located at downstream, filipin gene cluster NP_821588.1 CYP105P1, filipin gene cluster NP_821589.1 filipin gene cluster, PF00107: Zinc-binding dehydrogenase NP_821590.1 filipin gene cluster NP_821591.1 filipin gene cluster NP_821592.1 filipin gene cluster NP_821593.1 filipin gene cluster NP_821594.1 filipin gene cluster NP_821595.1 PF01526: Transposase NP_821596.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_821598.1 IS30 family, partial YP_187527.1 IS3 family, partial NP_821600.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_821603.1 PF03364: Streptomyces cyclase/dehydrase NP_821604.1 PF02627: Carboxymuconolactone decarboxylase family NP_821605.1 PF00106: short chain dehydrogenase NP_821607.1 PF02415: Chlamydia polymorphic membrane protein (Chlamydia_PMP) NP_821608.1 PF00135: Carboxylesterase NP_821612.1 PF01590: GAF domain NP_821615.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_821619.1 PF05593: RHS Repeat NP_821620.1 Tn4561 family, truncated NP_821621.1 IS630 family, truncated NP_821622.1 IS630 family, truncated NP_821626.1 PF01740: STAS domain NP_821632.1 PF04434: SWIM zinc finger NP_821634.1 PF00011: Hsp20/alpha crystallin family NP_821640.1 PF00190: Cupin doamin, 100% same as SAV878 NP_821643.1 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily NP_821644.1 PF03403: Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II NP_821645.1 PF01609: Transposase DDE domain NP_821646.1 PF01872: RibD C-terminal domain NP_821647.1 PF00165: Bacterial regulatory helix-turn-helix proteins, araC family NP_821651.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821654.1 IS630 family (630954..629809) Translation will be controlled by framenshift with SAV480. NP_821655.1 IS630 family (630954..629809) Target sequence (TA). NP_821666.1 PF01638: Transcriptional regulator NP_821672.1 probably pseudogene NP_821674.1 PF00320: GATA zinc finger YP_187528.1 IS5 family NP_821680.1 PF03992: Antibiotic biosynthesis monooxygenase NP_821681.1 PF07690: Major Facilitator Superfamily NP_821686.1 PF01966: HD domain NP_821687.1 PF00561: alpha/beta hydrolase fold NP_821688.1 PF01965: DJ-1/PfpI family NP_821690.1 PF01799: [2Fe-2S] binding domain NP_821691.1 PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain NP_821692.1 PF01527: Transposase NP_821694.1 PF00561: alpha/beta hydrolase fold NP_821695.1 PF01638: Transcriptional regulator NP_821709.1 PF00583: Acetyltransferase (GNAT) family NP_821716.1 PF00561: alpha/beta hydrolase fold NP_821718.1 PF02882: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NP_821719.1 PF00082: Subtilase family NP_821720.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate NP_821721.1 PF00107: Zinc-binding dehydrogenase NP_821722.1 PF00515: TPR Domain NP_821727.1 PF07690: Major Facilitator Superfamily NP_821735.1 PF03824: High-affinity nickel-transport protein NP_821736.1 PF00881: Nitroreductase family NP_821737.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase NP_821738.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate NP_821739.1 PF01557: Fumarylacetoacetate (FAA) hydrolase family NP_821742.1 PF01590: GAF domain NP_821743.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_821744.1 PF00561: alpha/beta hydrolase fold NP_821745.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_821746.1 PF03691: Uncharacterised protein family (UPF0167) NP_821747.1 PF07287: Protein of unknown function (DUF1446) NP_821749.1 PF00107: Zinc-binding dehydrogenase NP_821750.1 CYP102D1, bifunctional P450:NADPH-P450 reductase NP_821755.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_821759.1 CYP147B1, fdxA and fprA are located at upstream NP_821761.1 PF00989: PAS domain, PF01590: GAF domain NP_821762.1 PF01590: GAF domain NP_821764.1 PF00296: Luciferase-like monooxygenase NP_821765.1 PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region NP_821773.1 similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins NP_821775.1 PF00005: ABC transporter NP_821776.1 PF01032: FecCD transport family NP_821777.1 PF01497: Periplasmic binding protein NP_821778.1 nrps6 gene cluster NP_821779.1 nrps6 gene cluster, PF00550: Phosphopantetheine attachment site NP_821780.1 activates fatty acids by binding to coenzyme A NP_821781.1 nrps6 gene cluster NP_821782.1 nrps6 gene cluster, PF02668: Taurine catabolism dioxygenase TauD, TfdA family NP_821783.1 nrps6 gene cluster, PF00550: Phosphopantetheine attachment site NP_821784.2 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_821785.1 PF07690: Major Facilitator Superfamily NP_821786.1 PF05118: Aspartyl/Asparaginyl beta-hydroxylase NP_821788.1 PF04314: Protein of unknown function (DUF461) NP_821791.1 PF04314: Protein of unknown function (DUF461) NP_821792.1 PF00122: E1-E2 ATPase NP_821795.1 PF00561: alpha/beta hydrolase fold NP_821802.1 PF03663: Glycosyl hydrolase family 76 NP_821807.1 PF00754: F5/8 type C domain NP_821809.1 IS110 family NP_821811.1 PF01965: DJ-1/PfpI family NP_821817.1 PF05729: NACHT domain NP_821821.1 frameshift NP_821822.1 frameshift NP_821824.1 similar to aminonucleoside antibiotic A201A phosphotransferase NP_821827.1 probable membrane efflux protein, PF07690: Major Facilitator Superfamily NP_821828.1 PF00165: Bacterial regulatory helix-turn-helix proteins, araC family NP_821829.1 PF00248: Aldo/keto reductase family NP_821835.1 PF00753: Metallo-beta-lactamase superfamily NP_821840.1 PF00106: short chain dehydrogenase NP_821842.1 similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_821843.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821845.1 PF01609: Transposase DDE domain NP_821846.1 PF02452: PemK-like protein NP_821851.1 PF00107: Zinc-binding dehydrogenase NP_821852.1 PF05200: Glutamyl-tRNAGlu reductase, NAD(P) binding domain NP_821853.1 PF01638: Transcriptional regulator NP_821856.1 PF01636: Phosphotransferase enzyme family NP_821857.1 IS5 family NP_821862.1 PF03794: Domain of Unknown function NP_821872.1 PF01047: MarR family NP_821873.1 PF00989: PAS domain NP_821874.1 PF00106: short chain dehydrogenase NP_821877.1 PF01757: Acyltransferase family NP_821878.1 PF00583: Acetyltransferase (GNAT) family NP_821879.1 PF00583: Acetyltransferase (GNAT) family NP_821881.1 PF00107: Zinc-binding dehydrogenase NP_821882.1 PF03807: NADP oxidoreductase coenzyme F420-dependent NP_821883.1 PF00107: Zinc-binding dehydrogenase NP_821886.1 PF01638: Transcriptional regulator NP_821888.1 truncated NP_821890.1 PF00058: Low-density lipoprotein receptor repeat class B NP_821891.1 PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NP_821892.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_821894.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_821895.1 truncated NP_821897.1 truncated NP_821899.1 PF00106: short chain dehydrogenase NP_821905.1 PF01073: 3-beta hydroxysteroid dehydrogenase/isomerase family NP_821908.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821909.1 PF03572: Peptidase family S41B NP_821911.1 PF00126: Bacterial regulatory helix-turn-helix protein, lysR family NP_821912.1 PF00702: haloacid dehalogenase-like hydrolase NP_821913.1 PF05532: CsbD-like NP_821915.1 PF05239: PRC-barrel domain NP_821916.1 RNA polymerase alternative sigma factor NP_821917.1 PF00165: Bacterial regulatory helix-turn-helix proteins, araC family NP_821918.1 PF03995: Peptidase inhibitor family I36 NP_821926.1 ATP-dependent carboxylate-amine ligase NP_821927.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821930.1 PF00106: short chain dehydrogenase NP_821932.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_821933.1 PF00583: Acetyltransferase (GNAT) family NP_821935.1 PF00394: Multicopper oxidase NP_821942.1 PF00989: PAS domain, PF01590: GAF domain NP_821944.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821945.1 PF00106: short chain dehydrogenase NP_821949.1 PF01360: Monooxygenase NP_821950.1 similar to actII-1 NP_821953.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_821955.1 PF00296: Luciferase-like monooxygenase NP_821960.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821961.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; membrane protein NP_821962.1 weak similarity to chloramphenicol phosphotransferase NP_821963.1 PF02627: Carboxymuconolactone decarboxylase family NP_821964.1 PF00171: Aldehyde dehydrogenase family NP_821966.1 PF02133: Permease for cytosine/purines, uracil, thiamine, allantoin NP_821968.1 PF07681: DoxX NP_821969.1 amino acid permease NP_821970.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_821976.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis NP_821978.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate NP_821981.1 PF00515: TRP domain NP_821983.1 PF00989: PAS domain NP_821985.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_821988.1 PF05239: PRC-barrel domain NP_821991.1 PF05532: CsbD-like NP_821996.1 IS200/IS605 family NP_821997.1 IS200/IS605 family NP_822003.1 PF05592: Bacterial alpha-L-rhamnosidase NP_822008.1 PF00702: haloacid dehalogenase-like hydrolase NP_822011.1 PF01554: MatE NP_822013.1 CYP178A1, nrps7 gene cluster NP_822014.1 nrps7 gene cluster NP_822015.1 nrps7 gene cluster NP_822016.1 nrps7 gene cluster NP_822017.1 nrps7 gene cluster NP_822018.1 nrps7 gene cluster NP_822019.1 nrps7 gene cluster NP_822020.1 nrps7 gene cluster NP_822021.1 nrps7 gene cluster NP_822022.1 nrps7 gene cluster NP_822023.1 nrps7 gene cluster NP_822024.1 nrps7 gene cluster NP_822025.1 nrps7 gene cluster NP_822026.1 nrps7 gene cluster NP_822027.1 nrps7 gene cluster NP_822028.1 nrps7 gene cluster NP_822029.1 nrps7 gene cluster NP_822030.1 nrps7 gene cluster NP_822031.1 nrps7 gene cluster NP_822032.1 nrps7 gene cluster NP_822033.1 nrps7 gene cluster NP_822034.1 nrps7 gene cluster NP_822035.1 nrps7 gene cluster NP_822036.1 nrps7 gene cluster NP_822037.1 nrps7 gene cluster NP_822038.1 Catalyzes the formation of malnoyl-CoA, which in turn controls the rate of fatty acid metabolism NP_822039.1 nrps7 gene cluster NP_822040.1 nrps7 gene cluster NP_822041.1 nrps7 gene cluster NP_822042.1 nrps7 gene cluster NP_822043.1 nrps7 gene cluster NP_822044.1 nrps7 gene cluster NP_822046.1 PF05721: Phytanoyl-CoA dioxygenase (PhyH) NP_822047.1 PF00248: Aldo/keto reductase family NP_822048.1 PF03621: MbtH-like protein NP_822049.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_822050.1 PF00561: alpha/beta hydrolase fold NP_822052.1 similar to Cpt(Q56148) chloramphenicol-producing Streptomyces venezuelae. Streptomyces coelicolor A3(2) has different resistance mechanism (probably efflux, CmlR) NP_822053.1 PF00190: Cupin doamin, 100% same as SAV465 NP_822054.1 probably involving non-homologous end-joining NP_822056.1 PF01360: Monooxygenase NP_822058.1 PF01113: Dihydrodipicolinate reductase, N-terminus NP_822059.1 PF00665: Integrase core domain NP_822060.1 PF03992: Antibiotic biosynthesis monooxygenase NP_822061.1 PF00753: Metallo-beta-lactamase superfamily NP_822062.1 PF00754: F5/8 type C domain NP_822063.1 PF00561: alpha/beta hydrolase fold NP_822071.1 PF02342: Bacterial stress protein NP_822075.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822079.1 PF00248: Aldo/keto reductase family NP_822081.1 PF00561: alpha/beta hydrolase fold NP_822083.1 PF01073: 3-beta hydroxysteroid dehydrogenase/isomerase family NP_822085.1 PF03358: NADPH-dependent FMN reductase NP_822086.1 PF00106: short chain dehydrogenase NP_822087.1 PF01360: Monooxygenase NP_822089.1 PF00582: Universal stress protein family NP_822091.1 PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain NP_822092.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex NP_822093.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_822094.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_822096.1 PF01740: STAS domain NP_822097.1 PF00785: PAC motif NP_822098.1 PF00561: alpha/beta hydrolase fold NP_822099.1 PF01590: GAF domain NP_822101.1 a giant polypeptide 3338 aa NP_822110.1 positive response regulator for avermectin biosynthetic gene cluster, avermectin gene cluster NP_822111.1 avermectin gene cluster NP_822112.1 avermectin gene cluster NP_822113.1 avermectin gene cluster NP_822114.1 avermectin gene cluster NP_822115.1 avermectin gene cluster NP_822116.1 CYP171A1, avermectin gene cluster NP_822117.1 avermectin gene cluster NP_822118.1 avermectin gene cluster NP_822119.1 not involved in biosynthesis of avermectin, PF00106: short chain dehydrogenase NP_822120.1 avermectin gene cluster, PF00201: UDP-glucoronosyl and UDP-glucosyl transferase NP_822121.1 avermectin gene cluster NP_822122.1 avermectin gene cluster NP_822123.1 avermectin gene cluster NP_822124.1 avermectin gene cluster NP_822125.1 avermectin gene cluster NP_822126.1 avermectin gene cluster NP_822127.1 avermectin gene cluster NP_822128.1 avermectin gene cluster NP_822130.1 PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NP_822131.1 PF01590: GAF domain NP_822132.1 PF05532: CsbD-like NP_822135.1 PF04946: DGPF domain NP_822138.1 PF00107: Zinc-binding dehydrogenase NP_822139.1 PF02987: Late embryogenesis abundant protein NP_822140.1 PF01638: Transcriptional regulator NP_822141.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822143.1 PF02653: Branched-chain amino acid transport system / permease component NP_822148.1 PF07691: PA14 domain NP_822153.1 PF00665: Integrase core domain NP_822160.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_822161.1 PF05762: VWA domain containing CoxE-like protein NP_822167.1 PF03631: Ribonuclease BN-like family NP_822173.1 PF01435: Peptidase family M48 NP_822174.1 ATP-dependent carboxylate-amine ligase NP_822175.1 PF00089: Trypsin NP_822176.1 PF01593: Flavin containing amine oxidoreductase NP_822177.1 PF03364: Streptomyces cyclase/dehydrase NP_822178.1 PF00106: short chain dehydrogenase NP_822180.1 PF00571: CBS domain NP_822181.1 PF04226: Transglycosylase associated protein NP_822192.1 PF07300: Protein of unknown function (DUF1452) NP_822193.1 PF06532: Protein of unknown function (DUF1109) NP_822194.1 crt gene cluster, conversion of beta-carotene to isorenieratene NP_822195.1 crt gene cluster NP_822196.1 crt gene cluster NP_822197.2 crt gene cluster, probably geranylgeranyl pyrophosphate synthase NP_822198.1 crt gene cluster NP_822199.1 crt gene cluster NP_822200.1 crt gene cluster NP_822201.1 PF00652: QXW lectin repeat NP_822203.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_822208.1 PF05976: Bacterial membrane protein of unknown function (DUF893) NP_822211.1 PF00106: short chain dehydrogenase NP_822212.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_822214.1 PF00144: Beta-lactamase NP_822217.1 PF07690: Major Facilitator Superfamily NP_822219.1 PF04616: Glycosyl hydrolases family 43 NP_822224.1 PF04672: Protein of unknown function (DUF574) NP_822225.1 PF00248: Aldo/keto reductase family NP_822226.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_822227.1 PF04672: Protein of unknown function (DUF574) NP_822229.1 PF00989: PAS domain, PF01590: GAF domain NP_822230.1 PF03861: ANTAR domain NP_822234.1 PF04471: Restriction endonuclease NP_822235.1 PF03631: Ribonuclease BN-like family NP_822240.1 PF00043: Glutathione S-transferase, C-terminal domain NP_822242.1 PF00106: short chain dehydrogenase NP_822244.1 PF00753: Metallo-beta-lactamase superfamily NP_822249.1 PF00578: AhpC/TSA family NP_822250.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_822261.1 PF03861: ANTAR domain NP_822262.1 RNA polymerase alternative sigma factor NP_822263.1 PF05532: CsbD-like NP_822266.1 PF01740: STAS domain NP_822268.1 PF01590: GAF domain NP_822270.1 PF01740: STAS domain NP_822271.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_822272.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_822273.1 PF01590: GAF domain NP_822277.1 PF01740: STAS domain NP_822279.1 PF00501: AMP-binding enzyme NP_822281.1 PF02163: Peptidase family M50 NP_822286.1 PF04951: D-aminopeptidase NP_822287.1 PF02668: Taurine catabolism dioxygenase TauD, TfdA family NP_822291.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_822292.1 PF01433: Peptidase family M1 NP_822294.1 PF07690: Major Facilitator Superfamily NP_822295.1 PF01810: LysE type translocator NP_822296.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport NP_822299.1 PF02743: Cache domain NP_822302.1 PF01987: Protein of unknown function DUF124 NP_822303.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_822304.1 probably farnesyl pyrophosphate synthase NP_822305.1 PF00515: TPR Domain NP_822308.1 PF07690: Major Facilitator Superfamily NP_822309.1 PF01360: Monooxygenase NP_822311.1 melanin biosynthesis NP_822312.1 melanin biosynthesis NP_822313.1 PF00075: RNase H NP_822314.1 PF01047: MarR family NP_822315.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822316.1 PF00107: Zinc-binding dehydrogenase NP_822317.1 PF01590: GAF domain NP_822319.1 PF02210: Laminin G domain NP_822321.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_822322.1 PF00574: Clp protease NP_822324.1 PF01839: FG-GAP repeat NP_822326.1 RNA polymerase alternative sigma factor NP_822327.1 PF00781: Diacylglycerol kinase catalytic domain (presumed) NP_822331.1 PF00296: Luciferase-like monooxygenase NP_822337.1 PF00248: Aldo/keto reductase family NP_822340.1 catalyzes the formation of inosine from adenosine NP_822341.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822342.1 PF01435: Peptidase family M48 NP_822343.1 PF01047: MarR family NP_822344.1 PF01569: PAP2 superfamily NP_822345.1 PF01758: Sodium Bile acid symporter family NP_822346.1 CYP107F2 NP_822347.1 PF00248: Aldo/keto reductase family NP_822352.1 Activates fatty acids by binding to coenzyme A NP_822353.1 similar to Streptomyces griseus pabAB NP_822355.1 PF05547: Immune inhibitor A peptidase M6 NP_822358.1 PF04264: YceI like family NP_822362.1 PF00171: Aldehyde dehydrogenase family NP_822371.1 PF04946: DGPF domain NP_822372.1 PF02771: Acyl-CoA dehydrogenase, N-terminal domain NP_822373.1 IS630 family, partial NP_822375.1 PF00107: Zinc-binding dehydrogenase NP_822376.1 PF00107: Zinc-binding dehydrogenase NP_822380.1 PF00296: Luciferase-like monooxygenase NP_822381.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_822382.1 PF03358: NADPH-dependent FMN reductase NP_822383.1 PF00296: Luciferase-like monooxygenase NP_822386.1 PF01073: 3-beta-hydroxysteroid dehydrogenase/isomerase family NP_822388.1 PF01593: Flavin containing amine oxidoreductase NP_822389.1 probably regulates carotenoid biosynthesis NP_822390.1 probably regulates carotenoid biosynthesis NP_822391.1 PF03631: Ribonuclease BN-like family NP_822392.1 PF00753: Metallo-beta-lactamase superfamily NP_822394.1 PF03779: SPW repeat NP_822395.1 PF01636: Phosphotransferase enzyme family NP_822401.1 PF00583: Acetyltransferase (GNAT) family NP_822402.1 PF00583: Acetyltransferase (GNAT) family NP_822403.1 possible transporter NP_822404.1 PF00583: Acetyltransferase (GNAT) family NP_822405.1 PF03777: Small domain (DUF320) NP_822406.1 PF00561: alpha/beta hydrolase fold NP_822408.1 PF03465: eRF1 domain 3 NP_822409.1 inositol metabolism, PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_822410.1 PF00785: PAC motif NP_822412.1 PF01636: Phosphotransferase enzyme family NP_822416.1 homology to bldB, PF04149: Domain of unknown function (DUF397) NP_822417.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_822419.1 PF01796: Domain of unknown function DUF35 NP_822420.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_822421.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence NP_822423.1 PF01590: GAF domain NP_822424.1 nrps8 gene cluster NP_822425.1 nrps8 gene cluster NP_822426.1 nrps8 gene cluster NP_822427.1 multi-component regulatory system-1 NP_822428.1 multi-component regulatory system-1, PF03259: Roadblock/LC7 domain NP_822429.1 multi-component regulatory system-1, PF05331: Protein of unknown function (DUF742) NP_822430.1 multi-component regulatory system-1 NP_822431.1 PF00561: alpha/beta hydrolase fold NP_822433.1 activates fatty acids by binding to coenzyme A NP_822434.1 activates fatty acids by binding to coenzyme A NP_822435.1 PF03060: 2-nitropropane dioxygenase NP_822436.1 PF00144: Beta-lactamase NP_822439.1 PF01593: Flavin containing amine oxidoreductase NP_822442.1 PF02770: Acyl-CoA dehydrogenase, middle domain NP_822443.1 PF03860: Domain of Unknown Function (DUF326) NP_822447.1 PF00107: Zinc-binding dehydrogenase NP_822448.1 PF03894: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase NP_822452.1 PF05729: NACHT domain NP_822453.1 PF00027: Cyclic nucleotide-binding domain NP_822454.1 PF04672: Protein of unknown function (DUF574) NP_822455.1 PF00106: short chain dehydrogenase NP_822458.1 PF04235: Protein of unknown function (DUF418) NP_822459.1 PF00300: Phosphoglycerate mutase family NP_822460.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase NP_822461.1 PF02734: Dak2 domain NP_822462.1 PF03610: PTS system fructose IIA component NP_822463.1 PF07335: Fungal chitosanase NP_822464.1 PF00041: Fibronectin type III domain NP_822467.1 PF00724: NADH:flavin oxidoreductase / NADH oxidase family NP_822471.1 PF00583: Acetyltransferase (GNAT) family NP_822472.1 PF00107: Zinc-binding dehydrogenase NP_822473.1 PF00174: Oxidoreductase molybdopterin binding domain NP_822474.1 PF00970: Oxidoreductase FAD-binding domain NP_822477.1 PF05448: Acetyl xylan esterase (AXE1) NP_822483.1 CYP154D1 NP_822484.1 PF02771: Acyl-CoA dehydrogenase, N-terminal domain NP_822485.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_822486.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_822489.1 catalyzes the formation of glutamate from glutamine NP_822490.1 catalyzes the formation of fumarate from aspartate NP_822493.1 GntR-family transcriptional regulator NP_822494.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell NP_822495.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_822496.1 PF02641: Uncharacterized ACR, COG1993 NP_822497.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_822501.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_822505.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822507.1 PF02913: FAD linked oxidases, C-terminal domain NP_822509.1 membrane protein NP_822516.1 PF01636: Phosphotransferase enzyme family NP_822517.1 PF07690: Major Facilitator Superfamily NP_822518.1 PF00923: Transaldolase NP_822519.1 PF01593: Flavin containing amine oxidoreductase NP_822522.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_822523.1 PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NP_822524.1 converts acetoacetate to acetone and carbon dioxide NP_822525.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_822528.1 PF00754: F5/8 type C domain NP_822530.1 PF00795: Carbon-nitrogen hydrolase NP_822532.1 PF00107: Zinc-binding dehydrogenase NP_822538.1 PF01113: Dihydrodipicolinate reductase, N-terminus NP_822541.1 PF01447: Thermolysin metallopeptidase, catalytic domain NP_822542.1 PF00106: short chain dehydrogenase NP_822543.1 PF00107: Zinc-binding dehydrogenase NP_822544.1 PF04341: Protein of unknown function, DUF485 NP_822545.1 PF00474: Sodium:solute symporter family NP_822550.1 EC:2.6.1.9 NP_822551.1 PF07398: Protein of unknown function (DUF1503) NP_822553.1 PF07690: Major Facilitator Superfamily NP_822555.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_822556.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_822558.1 PF00702: haloacid dehalogenase-like hydrolase NP_822559.1 atoB: acetyl-CoA C-acetyltransferase, PF00108: Thiolase, N-terminal domain NP_822561.1 similar to glycolate oxidase: PF01565: FAD binding domain NP_822563.1 PF00857: Isochorismatase family NP_822565.1 PF00743: Flavin-binding monooxygenase-like NP_822566.1 PF00989: PAS domain, PF01590: GAF domain NP_822567.1 PF01590: GAF domain NP_822568.1 PF00107: Zinc-binding dehydrogenase NP_822579.1 PF00248: Aldo/keto reductase family NP_822580.1 PF04909: Amidohydrolase NP_822582.1 PF00041: Fibronectin type III domain NP_822593.1 PF00083: Sugar (and other) transporter NP_822594.1 PF01590: GAF domain NP_822595.1 PF00106: short chain dehydrogenase NP_822598.1 PF04932: O-Antigen Polymerase NP_822601.1 PF00535: Glycosyl transferase NP_822602.1 PF02342: Bacterial stress protein NP_822604.1 PF03473: MOSC domain, PF03476: MOSC N-terminal beta barrel domain NP_822606.1 ATPases of the AAA+ class, PF00004: ATPase family associated with various cellular activities (AAA) NP_822609.1 PF03364: Streptomyces cyclase/dehydrase NP_822618.1 alkylation damage repair NP_822621.1 PF01380: SIS domain NP_822623.1 PF07728: ATPase family associated with various cellular activities (AAA) NP_822624.1 PF05762: VWA domain containing CoxE-like protein NP_822630.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_822632.1 PF05448: Acetyl xylan esterase (AXE1) NP_822633.1 PF00534: Glycosyl transferases group 1 NP_822636.1 PF07690: Major Facilitator Superfamily NP_822638.1 PF07690: Major Facilitator Superfamily NP_822642.1 PF00107: Zinc-binding dehydrogenase NP_822644.1 PF04075: Domain of unknown function (DUF385) NP_822646.1 PF01546: Peptidase family M20/M25/M40 NP_822647.1 PF00753: Metallo-beta-lactamase superfamily NP_822654.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_822661.1 PF03483: B3/4 domain NP_822664.1 PF00106: short chain dehydrogenase NP_822668.1 PF00583: Acetyltransferase (GNAT) family NP_822669.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822670.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822671.1 PF00190: Cupin NP_822675.1 PF01435: Peptidase family M48 NP_822676.1 PF01569: PAP2 superfamily NP_822677.1 PF00702: haloacid dehalogenase-like hydrolase NP_822680.1 PF03713: Domain of unknown function (DUF305) NP_822685.1 PF00724: NADH:flavin oxidoreductase / NADH oxidase family NP_822688.1 PF02012: BNR/Asp-box repeat NP_822689.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_822690.1 PF03547: Auxin Efflux Carrier NP_822691.1 PF05976: Bacterial membrane protein of unknown function (DUF893) NP_822694.1 PF00106: short chain dehydrogenase NP_822695.1 catalyzes the formation of pyruvate from D-cysteine NP_822696.1 PF07336: Protein of unknown function (DUF1470) NP_822702.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_822703.1 PF01869: BadF/BadG/BcrA/BcrD ATPase family NP_822709.1 PF03861: ANTAR domain NP_822711.1 PF00702: haloacid dehalogenase-like hydrolase NP_822712.1 PF02625: XdhC and CoxI family NP_822713.1 frameshift NP_822714.1 frameshift, PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain NP_822715.1 PF00941: FAD binding domain in molybdopterin dehydrogenase NP_822718.1 PF01210: NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NP_822720.1 PF01757: Acyltransferase family NP_822722.1 PF02627: Carboxymuconolactone decarboxylase family NP_822726.1 pks2 gene cluster NP_822727.1 pks2 gene cluster NP_822728.1 pks2 gene cluster NP_822729.1 pks2 gene cluster NP_822730.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_822731.1 PF07690: Major Facilitator Superfamily NP_822733.1 PF01894: Uncharacterised protein family UPF0047 NP_822737.1 PF00296: Luciferase-like monooxygenase NP_822738.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_822748.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_822749.1 PF04307: Predicted membrane-bound metal-dependent hydrolase (DUF457) NP_822750.1 PF00270: DEAD/DEAH box helicase NP_822751.1 PF02551: Acyl-CoA thioesterase NP_822753.1 PF03259: Roadblock/LC7 domain NP_822754.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_822755.1 multi-component regulatory system-2 NP_822756.1 multi-component regulatory system-2, PF05331: Protein of unknown function (DUF742) NP_822757.1 multi-component regulatory system-2, PF03259: Roadblock/LC7 domain NP_822758.1 multi-component regulatory system-2 NP_822759.1 PF03707: Bacterial signalling protein N terminal repeat NP_822761.1 PF00561: alpha/beta hydrolase fold NP_822767.1 PF00487: Fatty acid desaturase NP_822771.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione NP_822773.1 PF00248: Aldo/keto reductase family NP_822774.1 PF00656: Caspase domain NP_822775.1 PF03745: Domain of unknown function (DUF309) NP_822776.1 catalyzes the formation of precorrin 6x from precorrin 5 NP_822777.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 NP_822778.1 PF01925: Domain of unknown function DUF81 NP_822779.1 PF00501: AMP-binding enzyme NP_822780.1 PF00108: Thiolase, N-terminal domain NP_822781.1 PF00210: ferritin-like domain NP_822782.1 PF00730: HhH-GPD superfamily base excision DNA repair protein NP_822783.1 PF01594: Domain of unknown function DUF20 NP_822787.1 CYP105Q1, fdxB and fprC are located at downstream NP_822789.1 PF00106: short chain dehydrogenase NP_822790.1 PF07690: Major Facilitator Superfamily NP_822791.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822794.1 PF02585: Uncharacterised LmbE-like protein, COG2120 NP_822797.1 PF00732: GMC oxidoreductase NP_822801.1 PF04944: Uncharacterised BCR (COG3801) NP_822803.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine NP_822804.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism NP_822805.1 PF01590: GAF domain NP_822806.1 multi-component regulatory system-3 NP_822807.1 multi-component regulatory system-3, PF05331: Protein of unknown function (DUF742) NP_822808.1 multi-component regulatory system-3, PF03259: Roadblock/LC7 domain NP_822809.1 multi-component regulatory system-3 NP_822810.1 PF00753: Metallo-beta-lactamase superfamily NP_822811.1 PF02627: Carboxymuconolactone decarboxylase family NP_822814.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_822816.1 PF01551: Peptidase family M23 NP_822822.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_822823.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_822824.1 PF04055: radical SAM superfamily domain NP_822825.1 PF01048: Phosphorylase family NP_822826.1 squalene/hopene gene cluster, shc NP_822827.1 squalene/hopene gene cluster, probably farnesyl pyrophosphate synthase NP_822828.1 squalene/hopene gene cluster, sqd NP_822829.1 squalene/hopene gene cluster, sqs1 NP_822830.1 squalene/hopene gene cluster, sqs2 NP_822839.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate NP_822849.1 PF00246: Zinc carboxypeptidase NP_822850.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue NP_822851.1 PF01433: Peptidase family M1 NP_822855.1 PF00106: short chain dehydrogenase NP_822856.1 similar to glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a: including enoyl-CoA hydratase; 3-2-trans-enoyl-CoA isomerase; 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase NP_822857.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_822858.1 PF02515: CoA-transferase family III NP_822862.1 PF02012: BNR/Asp-box repeat NP_822863.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_822870.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_822873.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth NP_822876.1 PF01144: Coenzyme A transferase NP_822877.1 PF01144: Coenzyme A transferase NP_822878.1 PF00108: Thiolase, N-terminal domain NP_822879.1 PF00775: Dioxygenase NP_822880.1 PF00775: Dioxygenase NP_822881.1 PF00206: Lyase NP_822882.1 PF02627: Carboxymuconolactone decarboxylase family NP_822884.1 PF00083: Sugar (and other) transporter NP_822885.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling NP_822890.1 PF03803: Scramblase NP_822891.1 PF04185: Phosphoesterase family NP_822898.1 PF03473: MOSC domain NP_822910.1 PF01266: FAD dependent oxidoreductase NP_822916.1 PF02743: Cache domain NP_822917.1 PF00989: PAS domain NP_822921.1 PF01360: Monooxygenase NP_822922.1 PF00561: alpha/beta hydrolase fold NP_822924.1 PF01648: 4'-phosphopantetheinyl transferase superfamily NP_822926.1 PF02222: ATP-grasp domain NP_822928.1 PF01120: Alpha-L-fucosidase NP_822937.1 PF02231: PHP domain N-terminal region NP_822938.1 similar to StaR of Streptomyces toyocaensis NRRL15009 NP_822939.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_822942.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_822943.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate NP_822944.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_822946.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_822947.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate NP_822949.1 PF05099: Tellurite resistance protein TerB NP_822950.1 PF03098: animal haem peroxidase NP_822953.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_822955.1 PF00083: Sugar (and other) transporter NP_822956.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_822958.1 PF07690: Major Facilitator Superfamily NP_822959.1 PF00144: Beta-lactamase NP_822960.1 PF07366: Protein of unknown function (DUF1486) NP_822963.1 PF03435: Saccharopine dehydrogenase NP_822964.1 PF05222: Alanine dehydrogenase/PNT, N-terminal domain NP_822968.1 PF02633: Creatinine amidohydrolase NP_822969.1 PF03706: Uncharacterised protein family (UPF0104) NP_822971.1 PF00534: Glycosyl transferases group 1 NP_822972.1 PF01242: 6-pyruvoyl tetrahydropterin synthase NP_822973.1 PF00107: Zinc-binding dehydrogenase NP_822974.1 PF01066: CDP-alcohol phosphatidyltransferase NP_822975.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_822976.1 PF00754: F5/8 type C domain NP_822983.1 PF00877: NlpC/P60 family NP_822985.1 PF01427: D-ala-D-ala dipeptidase NP_822986.1 frameshift NP_822987.1 frameshift NP_822992.1 PF00171: Aldehyde dehydrogenase family NP_822993.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_822994.1 catalyzes the interconversion of succinyl-CoA and succinate NP_822996.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA NP_822998.1 PF07690: Major Facilitator Superfamily NP_822999.1 PF07690: Major Facilitator Superfamily NP_823001.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_823002.1 PF00532: Periplasmic binding proteins and sugar binding domain of the LacI family NP_823007.1 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_823008.1 PF07690: Major Facilitator Superfamily NP_823009.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_823010.1 PF00384: Molybdopterin oxidoreductase NP_823013.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_823014.1 2,3-dihydroxy-2,3-dihydrobenzoate synthase, PF00857: Isochorismatase family NP_823016.1 PF00107: Zinc-binding dehydrogenase NP_823020.1 PF01758: Sodium Bile acid symporter family NP_823023.1 PF07690: Major Facilitator Superfamily NP_823024.1 PF00501: AMP-binding enzyme NP_823025.1 PF00248: Aldo/keto reductase family NP_823026.1 PF07335: Fungal chitosanase NP_823027.1 PF00106: short chain dehydrogenase NP_823034.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction NP_823040.1 PF00092: von Willebrand factor type A domain NP_823044.1 PF00753: Metallo-beta-lactamase superfamily NP_823045.1 PF00597: DedA family NP_823046.1 PF00753: Metallo-beta-lactamase superfamily NP_823049.1 RNA polymerase alternative sigma factor NP_823051.1 PF00571: CBS domain NP_823052.1 PF01965: DJ-1/PfpI family NP_823055.1 PF01569: PAP2 superfamily NP_823061.1 PF03364: Streptomyces cyclase/dehydrase NP_823065.1 similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins NP_823067.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_823068.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_823069.1 PF07332: Protein of unknown function (DUF1469) NP_823070.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_823072.1 PF00583: Acetyltransferase (GNAT) family NP_823073.1 PF02016: LD-carboxypeptidase NP_823074.1 PF00326: Prolyl oligopeptidase family NP_823075.1 PF01546: Peptidase family M20/M25/M40 NP_823076.1 PF04951: D-aminopeptidase NP_823077.1 PF05724: Thiopurine S-methyltransferase (TPMT) NP_823078.1 PF07228: Stage II sporulation protein E (SpoIIE) NP_823079.1 PF07690: Major Facilitator Superfamily NP_823080.1 PF03364: Streptomyces cyclase/dehydrase NP_823081.1 PF04055: Radical SAM superfamily NP_823082.1 PF00561: alpha/beta hydrolase fold NP_823083.1 PF00583: Acetyltransferase (GNAT) family NP_823084.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_823085.1 PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NP_823090.1 PF01575: MaoC like domain NP_823091.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_823092.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine NP_823093.1 PF01066: CDP-alcohol phosphatidyltransferase NP_823095.1 PF03747: ADP-ribosylglycohydrolase NP_823096.1 PF00293: NUDIX domain NP_823099.1 frameshift NP_823102.1 PF01839: FG-GAP repeat NP_823104.1 PF04087: Domain of unknown function (DUF389) NP_823105.1 PF04199: Putative cyclase NP_823106.1 PF00732: GMC oxidoreductase NP_823108.1 PF00723: Glycosyl hydrolases family 15 NP_823110.1 PF06029: AlkA N-terminal domain NP_823111.1 PF00355: Rieske [2Fe-2S] domain NP_823112.1 PF01593: Flavin containing amine oxidoreductase NP_823113.1 PF00459: Inositol monophosphatase family NP_823114.1 PF01019: Gamma-glutamyltranspeptidase NP_823117.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate NP_823118.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_823125.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position NP_823126.1 PF00795: Carbon-nitrogen hydrolase NP_823129.1 PF00795: Carbon-nitrogen hydrolase NP_823130.1 PF01391: Collagen triple helix repeat (20 copies) NP_823132.1 PF00557: metallopeptidase family M24 NP_823133.1 PF01019: Gamma-glutamyltranspeptidase NP_823135.1 PF02129: X-Pro dipeptidyl-peptidase (S15 family) NP_823136.1 ABC transporter permease NP_823137.1 ABC transporter permease NP_823138.1 ABC transporter substrate-binding protein NP_823139.1 ABC transporter ATP-binding protein NP_823141.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_823143.1 PF00753: Metallo-beta-lactamase superfamily NP_823144.1 PF02627: Carboxymuconolactone decarboxylase family NP_823145.1 IS110 family NP_823146.1 PF00106: short chain dehydrogenase NP_823149.1 PF00561: alpha/beta hydrolase fold NP_823150.1 PF00557: metallopeptidase family M24 NP_823153.1 PF04434: SWIM zinc finger NP_823160.1 PF07702: UbiC transcription regulator-associated NP_823161.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_823163.1 CYP107L2, adjacent to paaI NP_823165.1 similar to norsolorinic acid reductase, PF00248: Aldo/keto reductase family NP_823167.1 PF00545: ribonuclease NP_823168.1 PF00892: Integral membrane protein DUF6 NP_823169.1 PF01872: RibD C-terminal domain NP_823171.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate NP_823176.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle NP_823177.1 PF05169: Selenoprotein W-related family NP_823181.1 PF00092: von Willebrand factor type A domain NP_823184.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_823187.1 PF03061: Thioesterase superfamily NP_823188.1 PF01638: Transcriptional regulator NP_823189.1 PF07690: Major Facilitator Superfamily NP_823191.1 PF01374: Glycosyl hydrolase family 46 NP_823193.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. NP_823195.1 PF00576: Transthyretin precursor (formerly prealbumin) NP_823201.1 PF03446: NAD binding domain of 6-phosphogluconate dehydrogenase NP_823204.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate NP_823206.1 activates fatty acids by binding to coenzyme A NP_823210.1 PF00089: Trypsin NP_823216.1 MDM; functions in conversion of succinate to propionate NP_823217.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins NP_823219.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates NP_823220.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle NP_823221.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA NP_823222.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_823223.1 PF00300: Phosphoglycerate mutase family NP_823227.1 PF00144: Beta-lactamase NP_823228.1 PF04138: GtrA-like protein NP_823231.1 PF00107: Zinc-binding dehydrogenase NP_823234.1 PF03861: ANTAR domain NP_823237.1 CYP179A1 NP_823239.1 PF03364: Streptomyces cyclase/dehydrase NP_823241.1 PF02625: XdhC and CoxI family NP_823244.1 PF01799: [2Fe-2S] binding domain NP_823245.1 PF00941: FAD binding domain in molybdopterin dehydrogenase NP_823255.1 catalyzes the formation of acetate from pyruvate NP_823259.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_823260.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_823261.1 PF06029: AlkA N-terminal domain NP_823262.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity NP_823264.1 PF04055: Radical SAM superfamily NP_823265.1 PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NP_823267.1 repressor for sugar metabolism NP_823273.1 probably MDR transport NP_823275.1 PF00561: alpha/beta hydrolase fold NP_823278.1 PF00293: NUDIX domain NP_823281.1 PF00561: alpha/beta hydrolase fold NP_823283.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_823287.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines NP_823288.1 PF03747: ADP-ribosylglycohydrolase NP_823297.1 PF01113: Dihydrodipicolinate reductase, N-terminus NP_823298.1 PF03631: Ribonuclease BN-like family NP_823299.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_823305.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite NP_823307.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP NP_823308.1 frameshift NP_823309.1 frameshift NP_823313.1 PF01903: CbiX NP_823317.1 PF03176: MMPL family NP_823322.1 PF01636: Phosphotransferase enzyme family NP_823323.1 3'-5' exonuclease of DNA polymerase III NP_823331.1 PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NP_823332.1 PF00720: Subtilisin inhibitor-like NP_823335.1 PF00498: FHA domain NP_823337.1 PF00557: metallopeptidase family M24 NP_823338.1 PF00595: PDZ domain (Also known as DHR or GLGF) NP_823339.1 geosmin biosynthesis NP_823340.1 PF00561: alpha/beta hydrolase fold NP_823341.1 CYP180A1 NP_823342.1 PF01937: Protein of unknown function DUF89 NP_823344.1 PF03067: Chitin binding domain NP_823348.1 SgaA homolog, PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_823350.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_823352.1 regulatory protein, PF04149: Domain of unknown function (DUF397) NP_823353.1 PF04672: Protein of unknown function (DUF574) NP_823355.1 multi-component regulatory system-4 NP_823356.1 multi-component regulatory system-4, PF03259: Roadblock/LC7 domain NP_823357.1 multi-component regulatory system-4, PF05331: Protein of unknown function (DUF742) NP_823358.1 multi-component regulatory system-4 NP_823364.1 multi-component regulatory system-5 NP_823365.1 multi-component regulatory system-5, PF03259: Roadblock/LC7 domain NP_823366.1 multi-component regulatory system-5, PF05331: Protein of unknown function (DUF742) NP_823367.1 multi-component regulatory system-5 NP_823369.1 PF04205: FMN-binding domain NP_823370.1 PF01794: Ferric reductase like transmembrane component NP_823373.1 PF00733: Asparagine synthase NP_823375.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_823379.1 PF00702: haloacid dehalogenase-like hydrolase NP_823380.1 PF01641: SelR domain NP_823383.1 PF01872: RibD C-terminal domain NP_823388.1 PF01145: SPFH domain / Band 7 family NP_823389.1 PF05787: Bacterial protein of unknown function (DUF839) NP_823390.1 PF01522: Polysaccharide deacetylase NP_823392.1 PF01981: Domain of unknown function UPF0099 NP_823394.1 PF05114: Protein of unknown function (DUF692) NP_823397.1 PF06778: Chlorite dismutase NP_823398.1 frameshift NP_823399.1 frameshift NP_823401.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_823403.1 PF01694: Rhomboid family NP_823404.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_823407.1 PF01612: 3'-5' exonuclease NP_823409.1 PF00108: Thiolase, N-terminal domain NP_823410.1 similar to glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a: including enoyl-CoA hydratase; 3-2-trans-enoyl-CoA isomerase; 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase NP_823412.1 PF01066: CDP-alcohol phosphatidyltransferase NP_823418.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_823419.1 PF00324: Amino acid permease NP_823420.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_823426.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_823434.1 Catalyzes the conversion of citrate to isocitrate NP_823440.1 PF07690: Major Facilitator Superfamily NP_823442.1 PF00702: haloacid dehalogenase-like hydrolase NP_823443.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_823444.1 similar to gamma-butyrolactone-dependent transcriptional regulator NP_823445.1 homology to BarX, FarX, AfsA, and ScbA: containing A-factor biosynthesis repeat motif NP_823446.1 similar to gamma-butyrolactone-dependent transcriptional regulator NP_823447.2 VlmK homolog, PF03972: MmgE/PrpD family NP_823450.1 VlmJ homolog, PF00781: Diacylglycerol kinase catalytic domain (presumed) NP_823451.1 PF07690: Major Facilitator Superfamily NP_823452.1 pks3 gene cluster NP_823453.1 pks3 gene cluster NP_823454.1 pks3 gene cluster, PF00296: Luciferase-like monooxygenase NP_823455.1 activates fatty acids by binding to coenzyme A NP_823456.1 pks3 gene cluster NP_823457.1 pks3 gene cluster NP_823458.1 pks3 gene cluster NP_823459.1 PF00171: Aldehyde dehydrogenase family NP_823460.1 VlmH homolog NP_823462.1 PF03364: Streptomyces cyclase/dehydrase NP_823464.1 PF01613: Flavin reductase like domain NP_823465.1 VlmB homolog NP_823466.1 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_823467.1 PF00550: Phosphopantetheine attachment site NP_823468.1 PF00109: Beta-ketoacyl synthase, N-terminal domain NP_823470.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_823471.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_823473.1 PF07690: Major Facilitator Superfamily NP_823474.1 PF00487: Fatty acid desaturase NP_823476.1 VlmA homolog, PF04329: Family of unknown function (DUF470) NP_823479.1 PF01039: Carboxyl transferase domain NP_823481.1 PF01042: Endoribonuclease L-PSP NP_823482.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_823483.1 PF00501: AMP-binding enzyme NP_823485.1 PF00685: Sulfotransferase domain NP_823489.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP NP_823491.1 catalyzes the conversion of salicylyl-CoA to gentisyl-CoA NP_823492.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_823493.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_823495.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway NP_823497.1 PF01145: SPFH domain / Band 7 family NP_823498.1 PF03459: TOBE domain NP_823499.1 PF00149: Calcineurin-like phosphoesterase NP_823501.1 PF00296: Luciferase-like monooxygenase NP_823503.1 PF03819: MazG nucleotide pyrophosphohydrolase domain NP_823505.1 PF04472: Protein of unknown function (DUF552) NP_823513.1 PF07728: ATPase family associated with various cellular activities (AAA) NP_823518.1 PF00597: DedA family NP_823519.1 PF03706: Uncharacterised protein family (UPF0104) NP_823521.1 PF00106: short chain dehydrogenase NP_823522.1 cell wall surface anchor family protein NP_823527.1 PF03364: Streptomyces cyclase/dehydrase NP_823531.1 similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins NP_823534.1 PF00106: short chain dehydrogenase NP_823536.1 PF00583: Acetyltransferase (GNAT) family NP_823542.1 pks5 gene cluster NP_823543.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity NP_823544.1 pks5 gene cluster NP_823545.1 pks5 gene cluster NP_823546.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_823549.1 pks9 gene cluster, similar to actIORF3 NP_823550.1 pks9 gene cluster NP_823551.1 pks9 gene cluster, similar to actIORF2 NP_823552.1 pks9 gene cluster, similar to actIORF1 NP_823553.1 CYP107Y1, pks9 gene cluster NP_823554.1 pks9 gene cluster, PF01360: Monooxygenase NP_823555.1 pks9 gene cluster NP_823556.1 pks9 gene cluster NP_823557.1 pks9 gene cluster NP_823558.1 pks9 gene cluster NP_823559.1 pks9 gene cluster, similar to actVII NP_823560.1 pks9 gene cluster NP_823561.1 CYP181A1, pks9 gene cluster NP_823562.1 pks9 gene cluster NP_823563.1 pks9 gene cluster NP_823564.1 probably pseudogene NP_823567.1 PF02254: TrkA-N domain NP_823568.1 PF02254: TrkA-N domain NP_823571.1 PF00072: Response regulator receiver domain NP_823572.1 PF02702: Osmosensitive K+ channel His kinase sensor domain NP_823575.1 catalyzes the formation of dUMP from dUTP NP_823576.1 PF03061: Thioesterase superfamily NP_823580.1 transfer copper to melC NP_823582.1 spectinomycin resistance or Li+ sensitivity. extragenic suppressor protein homolog, PF00459: Inositol monophosphatase family NP_823583.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_823584.1 PF07690: Major Facilitator Superfamily NP_823585.1 PF01565: FAD binding domain NP_823589.1 SgaA homolog NP_823590.1 catalyzes the formation of thymidine 5'-phosphate from thymidine NP_823591.1 PF01663: Type I phosphodiesterase / nucleotide pyrophosphatase NP_823594.1 PF00381: PTS HPr component phosphorylation site NP_823596.1 PF01551: Peptidase family M23 NP_823597.1 PF05193: Peptidase M16 inactive domain NP_823598.1 PF05193: Peptidase M16 inactive domain NP_823599.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_823600.1 cobalamin biosynthesis, PF02492: CobW/HypB/UreG, nucleotide-binding domain NP_823604.1 PF00285: Citrate synthase NP_823605.1 PF06091: Bacterial protein of unknown function (DUF942) NP_823612.1 PF00474: Sodium:solute symporter family NP_823613.1 PF04341: Protein of unknown function, DUF485 NP_823618.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_823619.1 PF00089: Trypsin NP_823620.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released NP_823621.1 GntR-family transcriptional regulator NP_823623.1 PF00293: NUDIX domain NP_823626.1 PF00270: DEAD/DEAH box helicase NP_823629.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_823631.1 PF07690: Major Facilitator Superfamily NP_823633.1 PF03747: ADP-ribosylglycohydrolase NP_823634.1 PF00300: Phosphoglycerate mutase family NP_823637.1 catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis NP_823639.1 Represses a number of genes involved in the response to DNA damage NP_823641.1 PF00583: Acetyltransferase (GNAT) family NP_823647.1 PF01433: Peptidase family M1 NP_823648.1 PF04607: Region found in RelA / SpoT proteins NP_823649.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_823651.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_823654.1 PF02900: Catalytic LigB subunit of aromatic ring-opening dioxygenase NP_823655.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_823656.1 PF03819: MazG nucleotide pyrophosphohydrolase domain NP_823657.1 PF03466: LysR substrate binding domain NP_823660.1 ABC transporter ATP-binding protein NP_823661.1 ABC transporter substrate-binding protein NP_823662.1 ABC transporter permease NP_823663.1 ABC transporter permease NP_823664.1 PF01360: Monooxygenase NP_823665.1 PF05995: cysteine dioxygenase type I NP_823666.1 PF00581: Rhodanese-like domain NP_823667.2 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_823668.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_823670.1 PF01594: Domain of unknown function DUF20 NP_823673.1 PF06063: Domain of unknown function (DUF931) NP_823674.1 PF03591: AzlC protein NP_823676.1 PF00270: DEAD/DEAH box helicase NP_823677.1 involved in DNA repair; nick DNA at apurinic/apyrimidinic sites. PF01149: Formamidopyrimidine-DNA glycosylase N-terminal domain NP_823678.1 PF00106: short chain dehydrogenase NP_823680.1 PF00210: ferritin-like domain NP_823684.1 PF00919: Uncharacterized protein family UPF0004 NP_823689.1 PF01590: GAF domain NP_823690.1 PF01041: DegT/DnrJ/EryC1/StrS aminotransferase family NP_823691.1 PF00753: Metallo-beta-lactamase superfamily NP_823692.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_823693.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_823696.1 PF00515: TPR Domain NP_823697.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_823698.1 PF05193: Peptidase M16 inactive domain NP_823700.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_823701.1 PF01011: PQQ enzyme repeat NP_823702.1 PF01011: PQQ enzyme repeat NP_823703.1 PF04600: Protein of unknown function (DUF571) NP_823708.1 PF06013: Proteins of 100 residues with WXG NP_823710.1 PF00082: Subtilase family NP_823716.1 PF00082: Subtilase family NP_823717.1 PF05108: Protein of unknown function (DUF690) NP_823720.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_823722.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_823724.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_823725.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_823726.1 PF04456: Protein of unknown function (DUF503) NP_823727.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_823728.1 PF04296: Protein of unknown function (DUF448) NP_823729.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_823730.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_823733.1 homology to streptomycin 6-phosphotransferase NP_823734.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_823735.1 PF00583: Acetyltransferase (GNAT) family NP_823736.1 PF00583: Acetyltransferase (GNAT) family NP_823737.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_823738.1 PF02163: Peptidase family M50 NP_823739.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_823740.1 PF00932: Intermediate filament tail domain NP_823741.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_823743.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_823746.1 PF01055: Glycosyl hydrolases family 31 NP_823747.1 PF01670: Glycosyl hydrolase family 12 NP_823750.1 PF02012: BNR/Asp-box repeat NP_823754.1 PF01915: Glycosyl hydrolase family 3 C terminal domain NP_823756.1 frameshift NP_823757.1 frameshift NP_823759.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate NP_823760.1 PF01569: PAP2 superfamily NP_823762.1 frameshift NP_823763.1 frameshift NP_823764.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_823768.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation NP_823771.1 catalyzes the formation of inosine from adenosine NP_823776.1 PF07724: ATPase family associated with various cellular activities (AAA) NP_823778.1 PF02566: OsmC-like protein NP_823779.1 PF07690: Major Facilitator Superfamily NP_823781.1 PF03060: 2-nitropropane dioxygenase NP_823783.1 frameshift NP_823784.1 frameshift NP_823786.1 PF00171: Aldehyde dehydrogenase family NP_823791.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_823792.1 PF03641: Possible lysine decarboxylase NP_823797.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_823800.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_823801.1 Catalyzes the phosphorylation of UMP to UDP NP_823802.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_823803.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_823804.1 PF01551: Peptidase family M23 NP_823806.1 involved in the initiation of sporulation and glycogen biosynthesis NP_823809.1 PF02021: Uncharacterised protein family UPF0102 NP_823811.1 PF00293: NUDIX domain NP_823812.1 PF00717: Peptidase S24-like NP_823813.1 PF00717: Peptidase S24-like NP_823814.1 PF00717: Peptidase S24-like NP_823815.1 PF00717: Peptidase S24-like NP_823816.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_823817.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_823818.1 Essential for efficient processing of 16S rRNA NP_823820.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_823822.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_823825.2 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK NP_823826.1 regulatory protein for glutamine synthetase; glnB-homolog NP_823832.1 PF00296: Luciferase-like monooxygenase NP_823834.1 PF02483: SMC family, C-terminal domain NP_823835.1 catalyzes the hydrolysis of acylphosphate NP_823836.1 PF00188: SCP-like extracellular protein NP_823837.1 PF00258: Flavodoxin NP_823838.1 PF01638: Transcriptional regulator NP_823839.1 PF00144: Beta-lactamase NP_823840.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_823841.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_823842.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_823843.1 PF02620: Uncharacterized ACR, COG1399 NP_823844.1 PF05227: CHASE3 domain NP_823845.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_823847.1 PF00271: Helicase conserved C-terminal domain NP_823849.1 PF04012: PspA/IM30 family NP_823851.1 required for 70S ribosome assembly NP_823852.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_823853.1 PF01037: AsnC family NP_823855.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_823856.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_823858.1 PF01983: Protein of unknown function DUF121 NP_823860.1 PF00216: Bacterial DNA-binding protein NP_823861.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_823862.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_823866.1 PF00702: haloacid dehalogenase-like hydrolase NP_823867.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_823868.1 PF01557: Fumarylacetoacetate (FAA) hydrolase family NP_823870.1 multi-component regulatory system-6 NP_823871.1 multi-component regulatory system-6, PF03259: Roadblock/LC7 domain NP_823872.1 multi-component regulatory system-6, PF05331: Protein of unknown function (DUF742) NP_823873.1 multi-component regulatory system-6 NP_823874.1 multi-component regulatory system-7 NP_823875.1 multi-component regulatory system-7, PF03259: Roadblock/LC7 domain NP_823876.1 multi-component regulatory system-7, PF05331: Protein of unknown function (DUF742) NP_823877.1 multi-component regulatory system-7 NP_823879.1 PF01039: Carboxyl transferase domain NP_823880.1 PF02278: Polysaccharide lyase family 8, super-sandwich domain NP_823882.1 PF04264: YceI like family NP_823884.1 PF00933: Glycosyl hydrolase family 3 N terminal domain NP_823885.1 PF00652: QXW lectin repeat NP_823886.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA NP_823887.1 PF00083: Sugar (and other) transporter NP_823888.1 PF07676: WD40-like Beta Propeller Repeat NP_823891.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_823892.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_823893.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_823894.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_823898.1 PF00561: alpha/beta hydrolase fold NP_823904.1 PF07690: Major Facilitator Superfamily NP_823906.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_823907.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_823908.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_823909.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate NP_823910.1 PF00563: EAL domain NP_823911.1 PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NP_823912.1 PF00248: Aldo/keto reductase family NP_823913.1 PF05481: Mycobacterium 19 kDa lipoprotein antigen NP_823918.1 PF00583: Acetyltransferase (GNAT) family NP_823919.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_823921.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_823922.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_823923.1 PF00563: EAL domain NP_823924.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_823925.1 PF01717: Methionine synthase, vitamin-B12 independent NP_823926.1 PF00106: short chain dehydrogenase NP_823927.1 PF03641: possible lysine decarboxylase NP_823929.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_823930.1 PF01510: N-acetylmuramoyl-L-alanine amidase NP_823939.1 PF03458: UPF0126 domain NP_823940.1 PF01433: Peptidase family M1 NP_823941.1 tetra,pentapeptide transport system NP_823947.1 PF07179: SseB protein NP_823949.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein NP_823950.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_823951.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_823953.1 PF01183: Glycosyl hydrolases family 25 NP_823954.1 PF03473: MOSC domain NP_823955.1 PF03807: NADP oxidoreductase coenzyme F420-dependent NP_823956.1 PF00036: EF hand NP_823958.1 PF00583: Acetyltransferase (GNAT) family NP_823963.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_823964.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_823970.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_823971.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_823975.1 PF04149: Domain of unknown function (DUF397) NP_823977.1 PF00082: Subtilase family NP_823981.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_823982.1 CYP182A1 NP_823983.1 PF00580: UvrD/REP helicase NP_823988.1 PF00227: Proteasome A-type and B-type NP_823989.1 PF07690: Major Facilitator Superfamily NP_823991.1 PF00375: Sodium:dicarboxylate symporter family NP_823996.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_823998.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_823999.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate NP_824000.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_824001.1 glycolysis NP_824002.1 PF02987: Late embryogenesis abundant protein NP_824011.1 spore-pigment gene cluster, PF01360: Monooxygenase NP_824012.1 spore-pigment gene cluster, PF04486: SchA / CurD like protein NP_824013.1 spore-pigment gene cluster NP_824014.1 spore-pigment gene cluster, PF00109: Beta-ketoacyl synthase, N-terminal domain NP_824015.1 spore-pigment gene cluster, PF00109: Beta-ketoacyl synthase, N-terminal domain NP_824016.1 spore-pigment gene cluster, PF00550: Phosphopantetheine attachment site NP_824017.1 spore-pigment gene cluster, PF03364: Streptomyces cyclase/dehydrase NP_824018.1 spore-pigment gene cluster, PF04673: Polyketide synthesis cyclase NP_824020.1 PF07602: Protein of unknown function (DUF1565) NP_824024.1 PF01910: Domain of unknown function DUF77 NP_824026.1 PF01987: Protein of unknown function DUF124 NP_824027.1 PF01987: Protein of unknown function DUF124 NP_824028.1 PF01987: Protein of unknown function DUF124 NP_824030.1 PF07690: Major Facilitator Superfamily NP_824032.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis NP_824033.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_824034.1 PF02370: M protein repeat NP_824043.1 PF01939: Protein of unknown function DUF91 NP_824044.1 PF05729: NACHT domain NP_824045.1 PF01740: STAS domain NP_824046.1 PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NP_824056.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex NP_824057.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_824058.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_824059.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_824060.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_824061.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_824062.1 PF00137: ATP synthase subunit C NP_824063.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_824064.1 PF06942: GlpM protein NP_824065.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA NP_824066.1 concerning oligomycin biosynthesis NP_824068.1 oligomycin gene cluster NP_824069.1 oligomycin gene cluster NP_824070.1 CYP107W1, oligomycin gene cluster NP_824071.1 oligomycin gene cluster NP_824072.1 oligomycin gene cluster NP_824073.1 oligomycin gene cluster NP_824074.1 oligomycin gene cluster NP_824075.1 oligomycin gene cluster NP_824076.1 probably pseudogene NP_824077.1 oligomycin gene cluster NP_824078.1 oligomycin gene cluster NP_824079.1 oligomycin gene cluster NP_824081.1 PF01648: 4'-phosphopantetheinyl transferase superfamily NP_824085.1 PF01451: Low molecular weight phosphotyrosine protein phosphatase NP_824086.1 PF01300: yrdC domain NP_824088.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_824089.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_824091.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_824092.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_824093.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_824094.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_824095.1 PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain NP_824098.1 integrin homolog, PF01839: FG-GAP repeat NP_824099.1 integrin homolog, PF01839: FG-GAP repeat NP_824102.1 PF02463: RecF/RecN/SMC N terminal domain NP_824106.1 PF02463: RecF/RecN/SMC N terminal domain NP_824107.1 PF01507: Phosphoadenosine phosphosulfate reductase family NP_824112.1 PF00589: Phage integrase family NP_824115.1 PF02031: Streptomyces extracellular neutral proteinase (M7) family NP_824120.1 PF00109: Beta-ketoacyl synthase, N-terminal domain NP_824121.1 probably involving non-homologous end-joining NP_824122.1 ATP-dependent DNA ligase NP_824124.1 PF00782: Dual specificity phosphatase, catalytic domain NP_824127.1 PF01098: Cell cycle protein NP_824128.1 PF00905: Penicillin binding protein transpeptidase domain NP_824135.1 multi-component regulatory system-8 NP_824136.1 multi-component regulatory system-8, PF05331: Protein of unknown function (DUF742) NP_824137.1 multi-component regulatory system-8, PF03259: Roadblock/LC7 domain NP_824138.1 multi-component regulatory system-8 NP_824141.1 PF01183: Glycosyl hydrolases family 25 NP_824142.1 PF05362: Lon protease (S16) C-terminal proteolytic domain NP_824143.1 PF00583: Acetyltransferase (GNAT) family NP_824148.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth NP_824154.1 PF02861: Clp amino terminal domain NP_824156.1 PF00107: Zinc-binding dehydrogenase NP_824157.1 PF03949: Malic enzyme, NAD binding domain NP_824158.1 ABC transporter periplasmic component NP_824159.1 ABC transporter permease NP_824160.1 ABC transporter ATP-binding protein NP_824162.1 PF07336: Protein of unknown function (DUF1470) NP_824163.1 PF00717: Peptidase S24-like NP_824164.1 Ni-containing superoxide dismutase NP_824166.1 ptlK, probably pentalenolactone resistance gene NP_824167.1 pentalenolactone gene cluster, PF05721: Phytanoyl-CoA dioxygenase (PhyH) NP_824168.1 pentalenolactone gene cluster, PF07690: Major Facilitator Superfamily NP_824169.1 pentalenolactone gene cluster, PF00106: short chain dehydrogenase NP_824170.1 pentalenolactone gene cluster, PF00743: Flavin-binding monooxygenase-like NP_824171.1 pentalenolactone gene cluster, PF02668: Taurine catabolism dioxygenase TauD, TfdA family NP_824172.1 pentalenolactone gene cluster NP_824173.1 pentalenolactone gene cluster, probably farnesyl pyrophosphate synthase (idsA2) NP_824174.1 pentalenolactone gene cluster NP_824175.1 cyp13, CYP183A1, pentalenolactone gene cluster NP_824176.1 pentalenolactone gene cluster NP_824177.1 pentalenolactone gene cluster NP_824179.1 PF06108: Protein of unknown function (DUF952) NP_824181.1 PF00583: Acetyltransferase (GNAT) family NP_824182.1 probably farnesyl pyrophosphate synthase NP_824183.1 similar to sporulation-specific protein NP_824184.1 PF01510: N-acetylmuramoyl-L-alanine amidase NP_824186.1 PF00999: Sodium/hydrogen exchanger family NP_824187.1 PF02148: Zn-finger in ubiquitin-hydrolases and other protein NP_824188.1 rshA NP_824189.1 RNA polymerase alternative sigma factor NP_824191.1 PF00781: Diacylglycerol kinase catalytic domain (presumed) NP_824192.1 PF02467: Transcription factor WhiB NP_824194.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate NP_824199.1 PF07702: UbiC transcription regulator-associated NP_824201.1 PF00474: Sodium:solute symporter family NP_824207.1 CYP170A2 NP_824208.1 terpene biosynthesis NP_824211.1 PF01966: HD domain NP_824212.1 PF01966: HD domain NP_824214.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response NP_824216.1 PF02586: Uncharacterised ACR, COG2135 NP_824218.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_824219.1 PF03193: Protein of unknown function, DUF258 NP_824222.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_824227.1 PF00571: CBS domain NP_824230.1 PF00515: TPR Domain NP_824231.1 PF03699: Uncharacterised protein family (UPF0182) NP_824233.1 PF00595: PDZ domain (Also known as DHR or GLGF) NP_824236.1 PF01370: NAD dependent epimerase/dehydratase family NP_824238.1 PF00293: NUDIX domain NP_824239.1 PF01987: Protein of unknown function DUF124 NP_824240.1 PF01987: Protein of unknown function DUF124 NP_824241.1 PF01987: Protein of unknown function DUF124 NP_824242.1 PF01863: Protein of unknown function DUF45 NP_824243.1 PF00899: ThiF family NP_824250.1 PF00293: NUDIX domain NP_824251.1 PF01546: Peptidase family M20/M25/M40 NP_824254.1 PF01035: 6-O-methylguanine DNA methyltransferase, DNA binding domain NP_824255.1 PF03706: Uncharacterised protein family (UPF0104) NP_824256.1 PF00561: alpha/beta hydrolase fold NP_824257.1 PF00561: alpha/beta hydrolase fold NP_824258.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation NP_824264.1 oligopeptide transport NP_824265.1 oligopeptide transport NP_824266.1 oligopeptide transport NP_824268.1 PF00561: alpha/beta hydrolase fold NP_824274.1 PF00270: DEAD/DEAH box helicase NP_824275.1 PF00561: alpha/beta hydrolase fold NP_824278.1 PF01914: MarC family integral membrane protein NP_824279.1 PF02231: PHP domain N-terminal region NP_824287.1 PF06210: Protein of unknown function (DUF1003) NP_824290.1 mediates the export of protein precursors bearing twin-arginine signal peptides NP_824291.1 PF00089: Trypsin NP_824293.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence NP_824300.1 PF03641: Possible lysine decarboxylase NP_824301.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate NP_824304.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis NP_824306.1 PF00583: Acetyltransferase (GNAT) family NP_824314.1 mycothiol biosynthesis NP_824318.1 PF04149: Domain of unknown function (DUF397) NP_824320.1 PF00326: Prolyl oligopeptidase family NP_824326.1 ABC transporter periplasmic component NP_824327.1 ABC transporter periplasmic component NP_824328.1 ABC transporter periplasmic component NP_824329.1 ABC transporter ATP-binding protein NP_824331.1 nrps3 gene cluster NP_824332.1 nrps3 gene cluster NP_824333.1 nrps3 gene cluster, PF07690: Major Facilitator Superfamily NP_824334.1 nrps3 gene cluster NP_824335.1 nrps3 gene cluster NP_824336.1 nrps3 gene cluster NP_824337.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_824344.1 PF00583: Acetyltransferase (GNAT) family NP_824346.1 PF04978: Protein of unknown function (DUF664) NP_824349.1 ABC transporter ATP-binding protein NP_824350.1 ABC transporter periplasmic component NP_824351.1 ABC transporter periplasmic component NP_824352.1 ABC transporter periplasmic component NP_824354.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_824357.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_824358.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source NP_824361.1 PF01590: GAF domain NP_824369.1 PF01648: 4'-phosphopantetheinyl transferase superfamily NP_824370.1 PF00795: Carbon-nitrogen hydrolase NP_824371.1 PF06063: Domain of unknown function (DUF931) NP_824372.1 PF03591: AzlC protein NP_824373.1 nrps1 gene cluster NP_824374.1 nrps1 gene cluster NP_824375.1 nrps1 gene cluster NP_824376.1 nrps1 gene cluster, PF00106: short chain dehydrogenase NP_824377.1 nrps1 gene cluster NP_824378.1 nrps1 gene cluster NP_824379.1 nrps1 gene cluster, LuxR-family NP_824381.1 homology to AviX3 Streptomyces viridochromogenes, PF06769: Protein of unknown function (DUF1224) NP_824382.1 homology to AviX2 Streptomyces viridochromogenes, PF02604: Phd_YefM NP_824383.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_824385.1 PF00480: ROK family NP_824386.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_824387.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_824388.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_824389.1 PF00881: Nitroreductase family NP_824391.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese NP_824392.1 PF02467: Transcription factor WhiB NP_824396.1 PF05729: NACHT domain NP_824397.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_824398.1 PF04167: Protein of unknown function (DUF402) NP_824399.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_824401.1 PF00912: Transglycosylase NP_824402.1 PF01145: SPFH domain / Band 7 family NP_824406.1 PF02687: Predicted permease NP_824410.1 PF01594: Domain of unknown function DUF20 NP_824411.1 PF06737: Transglycosylase-like domain NP_824413.1 catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate NP_824414.1 PF02643: Uncharacterized ACR, COG1430 NP_824417.1 PF04978: Protein of unknown function (DUF664) NP_824418.1 PF00583: Acetyltransferase (GNAT) family NP_824420.1 PF01872: RibD C-terminal domain NP_824421.1 PF00691: OmpA family NP_824427.1 PF00482: Bacterial type II secretion system protein F domain NP_824428.1 PF00482: Bacterial type II secretion system protein F domain NP_824432.1 PF06981: Flp pilus assembly protein CpaB NP_824442.1 PF00246: Zinc carboxypeptidase NP_824444.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_824446.1 PF04956: Conjugal transfer protein TrbC NP_824448.1 PF00656: Caspase domain NP_824453.1 PF02447: GntP family permease NP_824454.1 PF01042: Endoribonuclease L-PSP NP_824457.1 PF01168: Alanine racemase, N-terminal domain NP_824458.1 PF01979: Amidohydrolase family NP_824461.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_824463.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP NP_824464.1 PF03006: Uncharacterised protein family (Hly-III / UPF0073) NP_824465.1 similar to monensin resistance protein MonT, PF07690: Major Facilitator Superfamily NP_824467.1 PF01927: Protein of unknown function DUF82 NP_824468.1 PF07250: Glyoxal oxidase N-terminus NP_824469.1 PF00535: Glycosyl transferase NP_824470.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_824471.1 PF00535: Glycosyl transferase NP_824472.1 PF03190: Protein of unknown function, DUF255 NP_824475.1 PF02585: Uncharacterised LmbE-like protein, COG2120 NP_824477.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_824478.1 catalyzes the formation of 2-oxobutanoate from L-threonine NP_824481.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine NP_824483.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_824488.1 PF03575: Peptidase family S51 NP_824489.1 PF01032: FecCD transport family NP_824492.1 PF01152: Bacterial-like globin NP_824495.1 PF00082: Subtilase family NP_824497.1 PF02687: Predicted permease NP_824498.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_824501.1 catalyzes the degradation of histidine to urocanate and ammmonia NP_824502.1 PF00990: GGDEF domain NP_824505.1 PF00211: Adenylate and Guanylate cyclase catalytic domain NP_824509.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_824511.1 PF02545: Maf-like protein NP_824513.1 biotin carboxylase and biotin carboxyl carrier protein NP_824514.1 PF00196: Bacterial regulatory proteins, luxR family NP_824516.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity NP_824518.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_824520.1 PF01545: Cation efflux family NP_824523.1 PF00171: Aldehyde dehydrogenase family NP_824524.1 PF00171: Aldehyde dehydrogenase family NP_824528.1 PF00072: Response regulator receiver domain NP_824529.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_824531.1 PF04892: VanZ like family NP_824532.1 PF04024: PspC domain NP_824534.1 catalyzes the formation of inosine from adenosine NP_824535.1 PF00326: Prolyl oligopeptidase family NP_824537.1 PF07690: Major Facilitator Superfamily NP_824538.1 binds the polymerase to DNA and acts as a sliding clamp NP_824539.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NP_824541.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate NP_824542.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis NP_824544.1 PF02653: Branched-chain amino acid transport system / permease component NP_824546.1 PF02608: Basic membrane protein NP_824548.1 PF01546: Peptidase family M20/M25/M40 NP_824555.1 PF01757: Acyltransferase family NP_824557.1 PF01360: Monooxygenase NP_824558.1 PF01810: LysE type translocator NP_824560.1 PF01471: Putative peptidoglycan binding domain NP_824565.1 PF01839: FG-GAP repeat NP_824574.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_824575.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase NP_824576.1 PF05154: TM2 domain NP_824578.1 PF05154: TM2 domain NP_824581.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_824583.1 PF04134: Protein of unknown function, DUF393 NP_824585.1 PF03176: MMPL family NP_824588.1 PF00149: Calcineurin-like phosphoesterase NP_824590.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_824591.1 PF03631: Ribonuclease BN-like family NP_824592.1 PF00106: short chain dehydrogenase NP_824594.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_824596.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_824600.1 PF00892: Integral membrane protein DUF6 NP_824603.1 PF04149: Domain of unknown function (DUF397) NP_824605.1 PF02627: Carboxymuconolactone decarboxylase family NP_824610.1 PF00732: GMC oxidoreductase NP_824612.1 PF04554: Extensin-like region NP_824613.1 catalyzes the oxidation of malate to oxaloacetate NP_824614.1 PF01381: Helix-turn-helix NP_824619.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_824620.1 PF06271: RDD family NP_824621.1 involved in de novo purine biosynthesis NP_824622.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_824628.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_824629.1 catalyzes the interconversion of succinyl-CoA and succinate NP_824630.1 threonine-rich protein NP_824632.1 PF05762: VWA domain containing CoxE-like protein NP_824634.1 PF07728: ATPase family associated with various cellular activities (AAA) NP_824635.1 PF04434: SWIM zinc finger NP_824639.1 PF01551: Peptidase family M23 NP_824641.1 Seems to have no N-terminal signal sequence NP_824642.1 PF03595: C4-dicarboxylate transporter/malic acid transport protein NP_824649.1 PF04024: PspC domain NP_824651.1 PF07681: DoxX NP_824655.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_824656.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_824659.1 PF00854: POT family NP_824664.1 PF00746: Gram positive anchor NP_824665.1 similar to sigma factor regulator prsI NP_824666.1 PF01740: STAS domain NP_824667.1 RNA polymerase alternative sigma factor NP_824668.1 PF00652: QXW lectin repeat NP_824670.1 catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway NP_824671.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate NP_824672.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide NP_824673.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism NP_824674.1 PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain NP_824677.1 PF03259: Roadblock/LC7 domain NP_824681.1 EC:4.3.1.3 NP_824688.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_824689.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_824693.1 PF06539: Protein of unknown function (DUF1112) NP_824694.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate NP_824695.1 PF01040: UbiA prenyltransferase family NP_824696.1 CYP107V1, pobA is located at downstream NP_824700.1 PF04140: Isoprenylcysteine carboxyl methyltransferase (ICMT) family NP_824706.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_824707.1 PF02541: Ppx/GppA phosphatase family NP_824708.1 PF04417: Protein of unknown function (DUF501) NP_824709.1 PF04977: Septum formation initiator NP_824710.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_824711.1 PF06737: Transglycosylase-like domain NP_824712.1 PF06737: Transglycosylase-like domain NP_824713.1 CYP107U2 NP_824714.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era NP_824719.1 weak homology to hsdM NP_824729.1 PF07690: Major Facilitator Superfamily NP_824730.1 PF04341: Protein of unknown function, DUF485 NP_824731.1 PF00474: Sodium:solute symporter family NP_824733.1 PF01391: Collagen triple helix repeat (20 copies) NP_824738.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_824739.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_824740.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_824741.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_824746.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_824747.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate NP_824750.1 PF00583: Acetyltransferase (GNAT) family NP_824756.1 PF07398: Protein of unknown function (DUF1503) NP_824759.1 PF01011: PQQ enzyme repeat NP_824762.1 PF01757: Acyltransferase family NP_824763.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis NP_824764.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_824765.1 PF03990: Domain of unknown function (DUF348) NP_824769.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_824770.1 PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region NP_824774.1 PF02683: Cytochrome C biogenesis protein transmembrane region NP_824778.1 PF00282: Pyridoxal-dependent decarboxylase conserved domain NP_824780.1 PF05223: NTF2-like N-terminal transpeptidase domain NP_824781.1 PF05223: NTF2-like N-terminal transpeptidase domain NP_824782.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_824790.1 PF00892: Integral membrane protein DUF6 NP_824791.1 PF04073: YbaK / prolyl-tRNA synthetases associated domain NP_824792.1 PF04149: Domain of unknown function (DUF397) NP_824795.1 PF03176: MMPL family NP_824797.1 PF03572: Peptidase family S41 NP_824800.1 PF00106: short chain dehydrogenase NP_824801.1 PF00561: alpha/beta hydrolase fold NP_824802.1 PF00743: Flavin-binding monooxygenase-like NP_824805.1 PF00583: Acetyltransferase (GNAT) family NP_824809.1 AfsR homolog, PF03704: Bacterial transcriptional activator domain NP_824810.1 PF00597: DedA family NP_824813.1 nrps2 gene cluster NP_824814.1 nrps2 gene cluster, PF01648: 4'-phosphopantetheinyl transferase superfamily NP_824815.1 nrps2 gene cluster NP_824816.1 nrps2 gene cluster NP_824817.1 nrps2 gene cluster, PF07690: Major Facilitator Superfamily NP_824818.1 nrps2 gene cluster NP_824819.1 nrps2 gene cluster NP_824820.1 nrps2 gene cluster, NRPS involved in dihydroxy-benzoyl-glycine biosynthesis NP_824821.1 nrps2 gene cluster NP_824822.1 nrps2 gene cluster NP_824823.1 nrps2 gene cluster NP_824824.1 nrps2 gene cluster NP_824825.1 nrps2 gene cluster NP_824826.1 nrps2 gene cluster NP_824827.1 nrps2 gene cluster, PF02770: Acyl-CoA dehydrogenase, middle domain NP_824828.1 nrps2 gene cluster NP_824830.1 pks8 gene cluster, PF00106: short chain dehydrogenase NP_824831.1 pks8 gene cluster NP_824832.1 pks8 gene cluster NP_824833.1 pks8 gene cluster NP_824834.1 pks8 gene cluster NP_824835.1 pks8 gene cluster NP_824836.1 pks8 gene cluster NP_824837.1 pks8 gene cluster NP_824838.1 pks8 gene cluster NP_824839.1 pks8 gene cluster, PF00561: alpha/beta hydrolase fold NP_824840.1 pks8 gene cluster NP_824841.1 pks8 gene cluster NP_824842.1 pks8 gene cluster NP_824843.1 pks8 gene cluster NP_824844.1 LuxR-family transcriptional regulatory protein NP_824847.1 probable molybdenum cofactor biosynthesis protein NP_824848.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_824852.1 PF01804: Penicillin amidase NP_824853.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli NP_824854.1 PF07690: Major Facilitator Superfamily NP_824856.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate NP_824857.1 PF06981: Flp pilus assembly protein CpaB NP_824860.1 PF06772: Bacterial low temperature requirement A protein (LtrA) NP_824861.1 PF03576: peptidase family T4 NP_824862.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_824868.1 PF07690: Major Facilitator Superfamily NP_824871.1 sigma-70 family NP_824872.1 PF00583: Acetyltransferase (GNAT) family NP_824873.1 PF02900: catalytic LigB subunit of aromatic ring-opening dioxygenase NP_824875.1 PF07690: Major Facilitator Superfamily NP_824881.1 CYP154B2, avaR is located at upstream NP_824884.1 PF00107: Zinc-binding dehydrogenase NP_824885.1 PF00589: Phage integrase family NP_824895.1 PF01507: Phosphoadenosine phosphosulfate reductase family NP_824896.1 SpdB homolog NP_824898.1 PF07702: UbiC transcription regulator-associated NP_824899.1 IS4 family NP_824903.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_824905.1 PF00589: Phage integrase family NP_824913.1 PF07702: UbiC transcription regulator-associated NP_824918.1 unclassified IS, PF00665: Integrase core domain NP_824929.1 PF01839: FG-GAP repeat NP_824932.1 PF01451: Low molecular weight phosphotyrosine protein phosphatase NP_824935.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_824938.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_824942.1 PF01041: DegT/DnrJ/EryC1/StrS aminotransferase family NP_824946.1 PF01433: Peptidase family M1 NP_824948.1 PF05672: E-MAP-115 family NP_824953.1 PF07690: Major Facilitator Superfamily NP_824957.1 PF07695: 7TM diverse intracellular signalling NP_824958.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_824959.1 PF05719: Golgi phosphoprotein 3 (GPP34) NP_824961.1 PF04149: Domain of unknown function (DUF397) NP_824963.1 PF00106: short chain dehydrogenase NP_824964.1 PF00474: Sodium:solute symporter family NP_824965.1 PF03747: ADP-ribosylglycohydrolase NP_824966.1 PF01839: FG-GAP repeat NP_824971.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis NP_824972.1 PF02231: PHP domain N-terminal region NP_824973.1 PF04075: Domain of unknown function (DUF385) NP_824975.1 PF00171: Aldehyde dehydrogenase family NP_824977.1 PF00296: Luciferase-like monooxygenase NP_824978.1 PF00106: short chain dehydrogenase NP_824979.1 PF00296: Luciferase-like monooxygenase NP_824980.1 PF04909: Amidohydrolase NP_824981.1 AfsR homolog, PF03704: Bacterial transcriptional activator domain NP_824983.1 activates fatty acids by binding to coenzyme A NP_824984.1 PF02803: Thiolase, C-terminal domain NP_824985.1 PF01796: Domain of unknown function DUF35 NP_824987.1 PF00561: alpha/beta hydrolase fold NP_824991.1 PF01638: Transcriptional regulator NP_824992.1 PF00107: Zinc-binding dehydrogenase NP_824993.1 AfsK homolog NP_824994.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_824996.1 PF00485: Phosphoribulokinase / Uridine kinase family NP_824997.1 PF04075: Domain of unknown function (DUF385) NP_824998.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_824999.1 PF02803: Thiolase, C-terminal domain NP_825002.1 PF01796: Domain of unknown function DUF35 NP_825003.1 PF07681: DoxX NP_825004.1 PF00743: Flavin-binding monooxygenase-like NP_825007.1 PF01613: flavin reductase like domain NP_825008.1 PF07690: Major Facilitator Superfamily NP_825010.1 PF00107: Zinc-binding dehydrogenase NP_825011.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825012.1 PF00106: short chain dehydrogenase NP_825013.1 PF04199: Putative cyclase NP_825015.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825016.1 PF02770: Acyl-CoA dehydrogenase, middle domain NP_825017.1 PF04909: Amidohydrolase NP_825018.1 similar to bifunctional enzyme MbtA: salicyl-AMP ligase + salicyl-S-ArCP synthetase. PF00501: AMP-binding enzyme NP_825020.1 PF01740: STAS domain NP_825022.1 PF01391: Collagen triple helix repeat (20 copies) NP_825023.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_825026.1 PF02757: YLP motif NP_825031.1 PF00561: alpha/beta hydrolase fold NP_825033.1 PF01380: SIS domain NP_825034.1 PF00989: PAS domain NP_825036.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle NP_825037.1 PF03171: 2OG-Fe(II) oxygenase superfamily NP_825040.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_825042.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825045.1 PF07287: Protein of unknown function (DUF1446) NP_825046.1 PF07398: Protein of unknown function (DUF1503) NP_825047.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_825048.1 PF00892: Integral membrane protein DUF6 NP_825053.1 PF01565: FAD binding domain NP_825054.1 multi-component regulatory system-9 NP_825055.1 multi-component regulatory system-9, PF03259: Roadblock/LC7 domain NP_825056.1 multi-component regulatory system-9, PF05331: Protein of unknown function (DUF742) NP_825057.1 multi-component regulatory system-9 NP_825058.1 CYP157A2, adjacent to multi-component regulatory system-9 NP_825059.1 CYP154C2, adjacent to CYP157A2 NP_825060.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate NP_825062.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_825063.1 PF02353: Cyclopropane-fatty-acyl-phospholipid synthase NP_825064.1 PF07690: Major Facilitator Superfamily NP_825067.1 PF00248: Aldo/keto reductase family NP_825068.1 PF00107: Zinc-binding dehydrogenase NP_825069.1 PF02834: 2',5' RNA ligase family NP_825070.1 PF00583: Acetyltransferase (GNAT) family NP_825071.1 PF07690: Major Facilitator Superfamily NP_825074.1 PF00860: Permease family NP_825076.1 PF00122: E1-E2 ATPase NP_825080.1 PF07690: Major Facilitator Superfamily NP_825082.1 PF01048: Phosphorylase family NP_825083.1 PF02642: Uncharacterized ACR, COG2107 NP_825085.1 PF00702: haloacid dehalogenase-like hydrolase NP_825096.1 PF01966: HD domain NP_825097.1 PF00494: Squalene/phytoene synthase NP_825101.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway NP_825102.1 PF02378: phosphotransferase system EIIC, PF00367: phosphotransferase system EIIB NP_825104.1 PF01740: STAS domain NP_825105.1 PF00989: PAS domain NP_825106.1 PF00724: NADH:flavin oxidoreductase / NADH oxidase family NP_825108.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_825110.1 PF02597: ThiS family NP_825111.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_825112.1 PF00535: Glycosyl transferase NP_825121.1 PF00990: GGDEF domain NP_825123.1 PF00472: Peptidyl-tRNA hydrolase domain NP_825124.1 PF02342: Bacterial stress protein NP_825129.1 PF01433: Peptidase family M1 NP_825131.1 PF00805: Pentapeptide repeats (8 copies) NP_825132.1 PF01593: Flavin containing amine oxidoreductase NP_825133.1 PF00107: Zinc-binding dehydrogenase NP_825134.1 PF07690: Major Facilitator Superfamily NP_825135.1 PF00583: Acetyltransferase (GNAT) family NP_825136.1 PF01266: FAD dependent oxidoreductase NP_825138.1 hydroxyurea resistance protein, PF04655: Aminoglycoside/hydroxyurea antibiotic resistance kinase NP_825141.1 PF00483: Nucleotidyl transferase NP_825142.1 PF07681: DoxX NP_825143.1 PF00588: SpoU rRNA Methylase family NP_825144.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_825145.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_825146.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_825148.1 PF04314: Protein of unknown function (DUF461) NP_825153.1 PF00248: Aldo/keto reductase family NP_825155.1 PF07690: Major Facilitator Superfamily NP_825156.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_825157.1 PF00589: Phage integrase family NP_825166.1 PF07702: UbiC transcription regulator-associated NP_825174.1 PF07366: Protein of unknown function (DUF1486) NP_825183.1 PF00534: Glycosyl transferases group 1 NP_825185.1 Seems to have a cleavable N-term signal sequence NP_825186.1 PF00072: Response regulator receiver domain NP_825188.1 PF05558: DREPP plasma membrane polypeptide NP_825191.1 PF00724: NADH:flavin oxidoreductase / NADH oxidase family NP_825195.1 PF00107: Zinc-binding dehydrogenase NP_825196.1 PF01636: Phosphotransferase enzyme family NP_825197.1 PF00702: haloacid dehalogenase-like hydrolase NP_825201.1 PF00583: Acetyltransferase (GNAT) family NP_825204.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_825205.1 PF01571: Glycine cleavage T-protein (aminomethyl transferase) NP_825211.1 PF02635: DsrE/DsrF-like family NP_825213.1 PF07210: Protein of unknown function (DUF1416) NP_825218.1 PF00326: Prolyl oligopeptidase family NP_825221.1 PF00089: Trypsin NP_825222.1 PF00089: Trypsin NP_825229.1 PF03023: MviN-like protein NP_825235.1 mycothiol biosynthesis NP_825246.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate NP_825248.1 PF00293: NUDIX domain NP_825250.1 PF00528: Binding-protein-dependent transport system inner membrane component NP_825252.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_825255.1 PF02583: Uncharacterised BCR, COG1937 NP_825258.1 PF01565: FAD binding domain NP_825259.1 PF01569: PAP2 superfamily NP_825260.1 PF00877: NlpC/P60 family NP_825262.1 PF00089: Trypsin NP_825265.1 PF04149: Domain of unknown function (DUF397) NP_825266.1 PF04149: Domain of unknown function (DUF397) NP_825269.1 PF00805: Pentapeptide repeats (8 copies) NP_825281.1 PF00583: Acetyltransferase (GNAT) family NP_825283.1 PF07690: Major Facilitator Superfamily NP_825285.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_825286.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_825289.1 PF00733: Asparagine synthase NP_825290.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_825291.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate NP_825292.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_825294.1 PF00248: Aldo/keto reductase family NP_825295.1 PF01551: Peptidase family M23 NP_825298.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate NP_825299.1 PF00324: Amino acid permease NP_825300.1 PF00270: DEAD/DEAH box helicase NP_825302.1 PF06262: Domain of unknown function (DUF1025) NP_825303.1 PF00149: Calcineurin-like phosphoesterase NP_825311.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_825312.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_825313.1 PF03724: Domain of unknown function (306) NP_825315.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_825316.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_825317.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway NP_825323.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_825325.1 similar to phage coat protein NP_825326.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_825327.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_825328.1 PF01590: GAF domain NP_825329.1 PF01433: Peptidase family M1 NP_825332.1 PF00270: DEAD/DEAH box helicase NP_825333.1 PF00571: CBS domain NP_825341.1 glycine-rich protein NP_825342.1 PF05239: PRC-barrel domain NP_825343.1 PF04234: Copper resistance protein CopC NP_825344.1 frameshift NP_825345.1 frameshift, PF00106: short chain dehydrogenase NP_825346.1 PF06172: Protein of unknown function (DUF985) NP_825347.1 alcB homolog NP_825348.1 PF01804: Penicillin amidase NP_825349.1 PF03729: Short repeat of unknown function (DUF308) NP_825350.1 PF03729: Short repeat of unknown function (DUF308) NP_825352.1 PF05872: Bacterial protein of unknown function (DUF853) NP_825355.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_825357.1 PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region NP_825358.1 phage integrase near tRNA gene, PF00589: Phage integrase family NP_825362.1 RNA polymerase alternative sigma factor NP_825363.1 RNA polymerase alternative sigma factor NP_825367.1 PF07690: Major Facilitator Superfamily NP_825368.1 PF04264: YceI like family NP_825371.1 homolog of virginiamycin S resistance gene (varS), PF07690: Major Facilitator Superfamily NP_825372.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_825373.1 homolog of dolichyl-phosphate beta-glucosyltransferase, PF04138: GtrA-like protein NP_825376.1 PF04909: Amidohydrolase NP_825377.1 PF03992: Antibiotic biosynthesis monooxygenase NP_825380.1 similar to cell wall lysis enzyme of phage; near tRNA genes NP_825381.1 PF00720: Subtilisin inhibitor-like NP_825383.1 activates fatty acids by binding to coenzyme A NP_825386.1 probably involved in the lipid metabolism, PF01575: MaoC like domain NP_825387.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825388.1 PF01796: Domain of unknown function DUF35 NP_825389.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825396.1 PF01580: FtsK/SpoIIIE family NP_825400.1 PF00089: Trypsin NP_825403.1 PF02810: SEC-C motif NP_825406.1 PF01590: GAF domain NP_825407.1 PF00557: metallopeptidase family M24 NP_825409.1 PF07690: Major Facilitator Superfamily NP_825411.1 PF00775: Dioxygenase NP_825412.1 PF01885: RNA 2'-phosphotransferase, Tpt1 / KptA family NP_825413.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_825416.1 PF02630: SCO1/SenC NP_825417.1 PF04314: Protein of unknown function (DUF461) NP_825418.1 PF04234: Copper resistance protein CopC NP_825419.1 PF04261: Dyp-type peroxidase family NP_825421.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_825422.1 PF00702: haloacid dehalogenase-like hydrolase NP_825429.1 PF00106: short chain dehydrogenase NP_825432.1 PF00296: Luciferase-like monooxygenase NP_825433.1 PF00702: haloacid dehalogenase-like hydrolase NP_825438.1 EC:2.6.1.9 NP_825440.1 PF00149: Calcineurin-like phosphoesterase NP_825442.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_825444.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_825447.1 PF00190: Cupin NP_825448.1 PF04020: Membrane protein of unknown function NP_825449.1 PF01451: Low molecular weight phosphotyrosine protein phosphatase NP_825450.1 catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine NP_825452.1 PF00293: NUDIX domain NP_825454.1 PF00702: haloacid dehalogenase-like hydrolase NP_825455.1 PF00583: Acetyltransferase (GNAT) family NP_825456.1 PF03928: Domain of unknown function (DUF336) NP_825457.1 similar to cmlR, PF07690: Major Facilitator Superfamily NP_825460.1 PF00144: Beta-lactamase NP_825463.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_825464.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_825465.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_825466.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_825468.1 PF02388: FemAB family NP_825469.1 PF01168: alanine racemase, N-terminal domain NP_825470.1 PF05007: Mannosyltransferase (PIG-M) NP_825471.1 PF00912: Transglycosylase NP_825473.1 PF01658: Myo-inositol-1-phosphate synthase NP_825474.1 PF07690: Major Facilitator Superfamily NP_825478.1 PF03023: MviN-like protein NP_825479.1 PF00069: Protein kinase domain NP_825480.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase NP_825484.1 PF00583: Acetyltransferase (GNAT) family NP_825485.1 PF02195: ParB-like nuclease domain NP_825486.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_825487.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_825489.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_825490.1 PF01809: Domain of unknown function DUF37 NP_825491.1 PF00825: Ribonuclease P NP_825492.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_825493.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_825494.1 binds the polymerase to DNA and acts as a sliding clamp NP_825495.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate NP_825496.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_825497.1 PF05258: Protein of unknown function (DUF721) NP_825498.1 negatively supercoils closed circular double-stranded DNA NP_825499.1 negatively supercoils closed circular double-stranded DNA NP_825507.1 PF01694: Rhomboid family NP_825508.1 integral membrane protein involved in inhibition of the Z-ring formation NP_825509.1 PF05949: Bacterial protein of unknown function (DUF881) NP_825510.1 PF04203: sortase family NP_825512.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity NP_825513.1 PF04203: sortase family NP_825514.1 PF04203: sortase family NP_825516.1 PF00905: Penicillin binding protein transpeptidase domain NP_825517.1 PF01098: Cell cycle protein NP_825518.1 PF00481: Protein phosphatase 2C NP_825519.1 PF00498: FHA domain NP_825520.1 PF00498: FHA domain NP_825522.1 PF01638: Transcriptional regulator NP_825524.1 PF00226: DnaJ domain NP_825525.1 PF00581: Rhodanese-like domain NP_825526.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825527.1 phenylacetate catabolism NP_825528.1 phenylacetate catabolism NP_825529.1 phenylacetate catabolism NP_825530.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation NP_825531.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA NP_825534.1 PF00588: SpoU rRNA Methylase family NP_825535.1 phenylacetate catabolism NP_825536.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation NP_825544.1 PF02254: TrkA-N domain NP_825545.1 PF00107: Zinc-binding dehydrogenase NP_825550.1 PF01636: Phosphotransferase enzyme family NP_825556.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_825558.1 PF07690: Major Facilitator Superfamily NP_825560.1 PF00795: Carbon-nitrogen hydrolase NP_825561.1 PF04525: Protein of unknown function (DUF567) NP_825563.1 frameshift, PF01436: NHL repeat NP_825564.1 frameshift, PF01436: NHL repeat NP_825566.1 catalyzes the removal of amino acids from the N termini of peptides NP_825567.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_825569.1 PF02678: Pirin, phage attachment site is located in the coding region. NP_825570.1 PF01594: Domain of unknown function DUF20 NP_825571.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_825572.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_825573.1 PF00775: Dioxygenase NP_825578.1 PF00583: Acetyltransferase (GNAT) family NP_825580.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_825581.1 PF00092: von Willebrand factor type A domain NP_825582.1 PF05787: Bacterial protein of unknown function (DUF839) NP_825584.1 PF02031: Streptomyces extracellular neutral proteinase (M7) family NP_825585.1 PF05976: Bacterial membrane protein of unknown function (DUF893) NP_825586.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_825587.1 PF00561: alpha/beta hydrolase fold NP_825588.1 frameshift NP_825589.1 frameshift NP_825592.1 PF01933: Uncharacterised protein family UPF0052; membrane protein NP_825600.1 PF00912: Transglycosylase NP_825603.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_825605.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_825609.1 PF00400: WD domain, G-beta repeat NP_825611.1 PF02450: Lecithin:cholesterol acyltransferase NP_825621.1 PF00702: haloacid dehalogenase-like hydrolase NP_825623.1 PF00270: DEAD/DEAH box helicase NP_825629.1 PF00144: Beta-lactamase NP_825632.1 PF00144: Beta-lactamase NP_825634.1 PF06626: Protein of unknown function (DUF1152) NP_825636.1 PF01186: Lysyl oxidase NP_825638.1 PF05257: CHAP domain NP_825639.1 PF03721: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NP_825640.1 similar to hyaluronate synthase, PF00535: Glycosyl transferase NP_825641.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_825645.1 PF07508: Recombinase NP_825648.1 PF01381: Helix-turn-helix NP_825649.1 PF04149: Domain of unknown function (DUF397) NP_825650.1 PF01839: FG-GAP repeat NP_825651.1 PF01839: FG-GAP repeat NP_825652.1 PF01839: FG-GAP repeat NP_825653.1 PF01839: FG-GAP repeat NP_825654.1 PF01839: FG-GAP repeat NP_825655.1 PF01839: FG-GAP repeat NP_825656.1 PF01839: FG-GAP repeat NP_825658.1 PF02389: Cornifin (SPRR) family NP_825660.1 PF00953: Glycosyl transferase NP_825661.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_825662.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_825663.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_825664.1 repressor of dnaK operon NP_825667.1 PF02467: Transcription factor WhiB NP_825684.1 PF01551: Peptidase family M23 NP_825685.1 PF01011: PQQ enzyme repeat NP_825690.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_825691.1 ATPases with chaperone activity, PF07724: ATPase family associated with various cellular activities (AAA) NP_825693.1 PF04188: Protein of unknown function (DUF409) NP_825696.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine NP_825697.1 PF06240: Carbon monoxide dehydrogenase subunit G (CoxG) NP_825698.1 PF01263: Aldose 1-epimerase NP_825699.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_825700.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_825701.1 PF07690: Major Facilitator Superfamily NP_825703.1 PF03301: Tryptophan 2,3-dioxygenase NP_825704.1 PF01053: Cys/Met metabolism PLP-dependent enzyme NP_825706.1 PF00498: FHA domain NP_825709.1 PF06259: Domain of unknown function (DUF1023) NP_825710.1 PF01757: Acyltransferase family NP_825715.1 PF04149: Domain of unknown function (DUF397) NP_825716.1 CYP107P2 NP_825719.1 PF01047: MarR family NP_825722.1 catalyzes the formation of acetaldehyde from ethanolamine NP_825724.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_825726.1 PF00535: Glycosyl transferase NP_825729.1 PF01965: DJ-1/PfpI family NP_825733.1 PF02575: Uncharacterised BCR, YbaB family COG0718 NP_825734.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_825736.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_825741.1 PF00326: Prolyl oligopeptidase family NP_825742.1 PF02254: TrkA-N domain NP_825743.1 PF01638: Transcriptional regulator NP_825747.1 PF00174: Oxidoreductase molybdopterin binding domain NP_825748.1 PF05724: Thiopurine S-methyltransferase (TPMT) NP_825752.1 PF00082: Subtilase family NP_825756.1 PF06259: Domain of unknown function (DUF1023) NP_825758.1 PF00149: Calcineurin-like phosphoesterase NP_825759.1 PF02637: GatB/Yqey domain NP_825760.1 PF00912: Transglycosylase NP_825761.1 PF02467: Transcription factor WhiB NP_825762.1 PF02374: Anion-transporting ATPase NP_825763.1 PF02374: Anion-transporting ATPase NP_825765.1 PF01042: Endoribonuclease L-PSP NP_825766.1 PF00293: NUDIX domain NP_825767.1 PF00753: Metallo-beta-lactamase superfamily NP_825768.1 PF01909: Nucleotidyltransferase domain NP_825771.1 PF00293: NUDIX domain NP_825772.1 PF00089: Trypsin NP_825773.1 PF00561: alpha/beta hydrolase fold NP_825774.1 PF07332: Protein of unknown function (DUF1469) NP_825775.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH NP_825776.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA NP_825777.1 PF00916: Sulfate transporter family NP_825779.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_825782.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_825783.1 PF00437: Type II/IV secretion system protein NP_825784.1 PF00482: Bacterial type II secretion system protein F domain NP_825790.1 PF00270: DEAD/DEAH box helicase NP_825791.1 PF01740: STAS domain NP_825793.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient NP_825798.1 PF01131: DNA topoisomerase NP_825799.1 PF02223: Thymidylate kinase NP_825800.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_825801.1 PF00561: alpha/beta hydrolase fold NP_825802.1 integrated tRNA gene, PF00589: Phage integrase family NP_825805.1 PF01590: GAF domain NP_825806.1 PF03861: ANTAR domain NP_825808.1 PF03861: ANTAR domain NP_825812.1 similar to AfsR, PF03704: Bacterial transcriptional activator domain NP_825817.1 PF05481: Mycobacterium 19 kDa lipoprotein antigen NP_825818.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_825819.1 required for 70S ribosome assembly NP_825820.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_825821.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_825822.1 PF07683: Cobalamin synthesis protein cobW C-terminal domain NP_825823.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_825827.1 PF00171: Aldehyde dehydrogenase family NP_825828.1 PF04978: Protein of unknown function (DUF664) NP_825832.1 PF00282: Pyridoxal-dependent decarboxylase conserved domain NP_825833.1 PF00654: Voltage gated chloride channel NP_825835.1 PF01906: Domain of unknown function DUF74 NP_825836.1 PF00597: DedA family NP_825837.1 PF06738: Protein of unknown function (DUF1212) NP_825839.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_825841.1 PF01171: PP-loop family NP_825844.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_825846.1 folic acid biosynthesis NP_825847.1 folic acid biosynthesis NP_825849.1 folic acid biosynthesis NP_825850.1 PF04329: Family of unknown function (DUF470) NP_825851.1 PF00756: Putative esterase NP_825853.1 PF03703: Bacterial membrane flanked domain NP_825854.1 PF03703: Bacterial membrane flanked domain NP_825856.1 PF02636: Uncharacterized ACR, COG1565 NP_825863.1 PF01210: NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NP_825864.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_825865.1 catalyzes the formation of oxaloacetate from L-aspartate NP_825866.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_825867.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP NP_825871.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis NP_825874.1 PF07724: ATPase family associated with various cellular activities (AAA) NP_825877.1 PF01551: Peptidase family M23 NP_825879.1 PF07690: Major Facilitator Superfamily NP_825880.1 similar to AfsQ2 NP_825881.1 similar to AfsQ1 NP_825884.1 G/C -> T/A transversion NP_825886.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair NP_825887.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_825890.1 PF02541: Ppx/GppA phosphatase family NP_825891.1 PF01261: AP endonuclease family 2 NP_825893.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_825894.1 AfsK homolog NP_825898.1 PF00916: Sulfate transporter family NP_825902.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_825903.1 PF00702: haloacid dehalogenase-like hydrolase NP_825905.1 PF07690: Major Facilitator Superfamily NP_825915.1 modulates transcription in response to the NADH/NAD(+) redox state NP_825916.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_825917.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_825919.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_825922.1 PF04672: Protein of unknown function (DUF574) NP_825925.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_825926.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine NP_825930.1 PF01139: Uncharacterized protein family UPF0027 NP_825932.1 PF00106: short chain dehydrogenase NP_825935.1 PF01638: Transcriptional regulator NP_825936.1 PF00107: Zinc-binding dehydrogenase NP_825937.1 PF07690: Major Facilitator Superfamily NP_825938.1 PF00583: Acetyltransferase (GNAT) family NP_825940.1 PF00296: Luciferase-like monooxygenase NP_825942.1 PF03929: PepSY-associated TM helix NP_825943.1 PF00534: Glycosyl transferases group 1 NP_825946.1 PF03023: MviN-like protein NP_825952.1 PF00583: Acetyltransferase (GNAT) family NP_825954.1 PF03713: Domain of unknown function (DUF305) NP_825956.1 catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide NP_825957.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_825964.1 PF01740: STAS domain NP_825966.1 PF04672: Protein of unknown function (DUF574) NP_825968.1 PF00892: Integral membrane protein DUF6 NP_825969.1 PF01118: Semialdehyde dehydrogenase, NAD binding domain NP_825972.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_825974.1 PF01522: Polysaccharide deacetylase NP_825975.1 PF00578: AhpC/TSA family NP_825980.1 PF01094: Receptor family ligand binding region NP_825982.1 PF03171: 2OG-Fe(II) oxygenase superfamily NP_825983.1 PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region NP_825984.1 PF00583: Acetyltransferase (GNAT) family NP_825986.1 PF01977: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_825987.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin NP_825988.1 PF02441: Flavoprotein NP_825990.1 PF04055: Radical SAM superfamily NP_825991.1 PF00583: Acetyltransferase (GNAT) family NP_825994.1 PF01575: MaoC like domain NP_825995.1 PF00501: AMP-binding enzyme NP_825998.1 PF02621: Uncharacterized ACR, COG1427 NP_826001.1 PF01478: Type IV leader peptidase family NP_826002.1 PF04055: radical SAM superfamily domain NP_826004.1 PF00704: Glycosyl hydrolases family 18 NP_826006.1 PF01522: Polysaccharide deacetylase NP_826007.1 PF01757: Acyltransferase family NP_826008.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_826009.1 PF03884: Domain of unknown function (DUF329) NP_826010.1 PF03793: PASTA domain NP_826011.1 PF00583: Acetyltransferase (GNAT) family NP_826012.1 PF01494: FAD binding domain NP_826013.1 Seems to have no N-terminal signal sequence NP_826014.1 Catalyzes the transfer of electrons from NADH to quinone NP_826015.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen NP_826016.1 Catalyzes the transfer of electrons from NADH to quinone NP_826017.1 Catalyzes the transfer of electrons from NADH to quinone NP_826018.1 Catalyzes the transfer of electrons from NADH to quinone NP_826020.1 Catalyzes the transfer of electrons from NADH to quinone NP_826021.1 Catalyzes the transfer of electrons from NADH to quinone NP_826022.1 Catalyzes the transfer of electrons from NADH to quinone NP_826023.1 Catalyzes the transfer of electrons from NADH to quinone NP_826024.1 Catalyzes the transfer of electrons from NADH to quinone NP_826025.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_826026.1 Catalyzes the transfer of electrons from NADH to quinone NP_826027.1 Catalyzes the transfer of electrons from NADH to quinone NP_826028.1 PF00270: DEAD/DEAH box helicase NP_826029.1 PF00890: FAD binding domain NP_826034.1 PF07702: UbiC transcription regulator-associated NP_826037.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_826038.1 PF00702: haloacid dehalogenase-like hydrolase NP_826039.1 PF01464: Transglycosylase SLT domain NP_826040.1 PF02129: Pro dipeptidyl-peptidase (S15 family) NP_826041.1 probably geranylgeranyl pyrophosphate synthase NP_826043.1 PF03548: Outer membrane lipoprotein carrier protein LolA NP_826046.1 PF02525: Flavodoxin-like fold NP_826049.1 PF04389: Peptidase family M28 NP_826050.1 PF00892: Integral membrane protein DUF6 NP_826051.1 PF01113: Dihydrodipicolinate reductase, N-terminus NP_826052.1 PF01638: Transcriptional regulator NP_826053.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin NP_826054.1 PF01855: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain NP_826058.1 similar to many chloroplastic ubiquinone dehydrogenase NP_826059.1 similar to many eukaryotic ubiquinone dehydrogenase NP_826060.1 PF00329: Respiratory-chain NADH dehydrogenase, 30 Kd subunit NP_826066.1 PF05921: Actinomycete protein of unknown function (DUF875) NP_826068.1 putative metalloprotease NP_826069.1 PF03733: Domain of unknown function (DUF307) NP_826072.1 PF04226: Transglycosylase associated protein NP_826073.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription NP_826074.1 PF01546: Peptidase family M20/M25/M40 NP_826075.1 PF00106: short chain dehydrogenase NP_826076.1 PF01979: Amidohydrolase family NP_826077.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif NP_826078.1 PF05921: Actinomycete protein of unknown function (DUF875) NP_826079.1 PF01575: MaoC like domain NP_826081.1 drug resistance, PF07690: Major Facilitator Superfamily NP_826082.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_826083.1 catalyzes the formation of inosine from adenosine NP_826084.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_826085.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_826087.1 binds directly to 23S ribosomal RNA NP_826088.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_826089.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_826090.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_826091.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_826092.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_826094.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_826095.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_826096.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_826097.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_826099.1 PF06821: Protein of unknown function (DUF1234) NP_826101.1 PF02585: Uncharacterised LmbE-like protein, COG2120 NP_826102.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_826103.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_826104.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_826105.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_826106.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_826107.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_826108.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_826109.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_826110.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_826111.1 one of the stabilizing components for the large ribosomal subunit NP_826112.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_826113.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_826114.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_826115.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_826116.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif NP_826117.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_826118.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_826119.1 binds 5S rRNA along with protein L5 and L25 NP_826120.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_826121.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_826122.1 late assembly protein NP_826123.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_826124.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_826125.1 PF00557: metallopeptidase family M24 NP_826126.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_826127.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_826128.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_826129.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_826130.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_826131.1 is a component of the macrolide binding site in the peptidyl transferase center NP_826132.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_826134.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_826135.1 forms a direct contact with the tRNA during translation NP_826136.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_826137.1 PF04087: Domain of unknown function (DUF389) NP_826138.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_826140.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_826141.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_826142.1 PF03853: YjeF-related protein N-terminus NP_826143.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_826145.1 PF00561: alpha/beta hydrolase fold NP_826146.1 PF02367: Uncharacterised P-loop hydrolase UPF0079 NP_826149.1 PF00814: glycoprotease family NP_826150.1 probably ribosomal-protein-alanine N-acetyltransferase NP_826151.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_826154.1 PF04149: Domain of unknown function (DUF397) NP_826161.1 PF00331: Glycosyl hydrolase family 10 NP_826163.1 PF04946: DGPF domain NP_826166.1 PF01522: Polysaccharide deacetylase NP_826167.1 PF01522: Polysaccharide deacetylase NP_826168.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_826169.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth NP_826170.1 PF07366: Protein of unknown function (DUF1486) NP_826171.1 PF00106: short chain dehydrogenase NP_826172.1 PF03473: MOSC domain NP_826174.1 PF02467: Transcription factor WhiB NP_826176.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase NP_826178.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_826179.1 PF00984: UDP-glucose/GDP-mannose dehydrogenase family, central domain NP_826181.1 PF00144: Beta-lactamase NP_826189.1 PF04149: Domain of unknown function (DUF397) NP_826192.1 PF00781: Diacylglycerol kinase catalytic domain (presumed) NP_826193.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate NP_826194.1 PF01266: FAD dependent oxidoreductase NP_826197.1 PF04138: GtrA-like protein NP_826198.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_826200.1 PF01244: Membrane dipeptidase (Peptidase family M19) NP_826201.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_826203.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_826204.1 PF00702: haloacid dehalogenase-like hydrolase NP_826205.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826206.1 PF03061: Thioesterase superfamily NP_826207.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826208.1 PF00535: Glycosyl transferase NP_826209.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826210.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826211.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826213.1 PF01510: N-acetylmuramoyl-L-alanine amidase NP_826214.1 PF00483: Nucleotidyl transferase NP_826216.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0) NP_826217.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) NP_826218.1 PF05995: cysteine dioxygenase type I NP_826219.1 PF02467: Transcription factor WhiB NP_826220.1 PF00535: Glycosyl transferase NP_826225.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells NP_826226.1 PF03966: Protein of unknown function (DUF343) NP_826230.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine NP_826231.1 PF06271: RDD family NP_826232.1 PF06271: RDD family NP_826233.1 PF01944: Integral membrane protein DUF95 NP_826234.1 PF01882: Protein of unknown function DUF58 NP_826238.1 PF07415: Gammaherpesvirus latent membrane protein (LMP2) protein NP_826243.1 PF00156: Phosphoribosyl transferase domain NP_826244.1 PF02482: Sigma 54 modulation protein / S30EA ribosomal protein NP_826246.1 PF06224: Protein of unknown function (DUF1006) NP_826247.1 PF00583: Acetyltransferase (GNAT) family NP_826248.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_826252.1 PF05088: Bacterial NAD-glutamate dehydrogenase NP_826253.1 PF04138: GtrA-like protein NP_826257.1 teichoic acid translocation transport system NP_826260.1 PF03747: ADP-ribosylglycohydrolase NP_826262.1 PF00106: short chain dehydrogenase NP_826270.1 PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NP_826271.1 PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NP_826272.1 PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NP_826276.1 PF00498: FHA domain NP_826279.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_826281.1 ABC transporter ATP-binding protein NP_826283.1 PF03572: Peptidase family S41 NP_826284.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_826288.1 CYP184A1 NP_826289.1 PF07690: Major Facilitator Superfamily NP_826293.1 PF01757: Acyltransferase family NP_826295.1 PF03364: Streptomyces cyclase/dehydrase NP_826296.1 PF07690: Major Facilitator Superfamily NP_826297.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane NP_826299.1 PF07336: Protein of unknown function (DUF1470) NP_826300.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and or membrane proteins NP_826303.1 PF03949: Malic enzyme, NAD binding domain NP_826304.1 PF00216: Bacterial DNA-binding protein NP_826305.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_826306.1 PF02622: Uncharacterized ACR, COG1678 NP_826312.1 PF00941: FAD binding domain in molybdopterin dehydrogenase NP_826313.1 PF01799: [2Fe-2S] binding domain NP_826314.1 PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain NP_826316.1 PF07690: Major Facilitator Superfamily NP_826317.1 PF04851: Type III restriction enzyme, res subunit NP_826318.1 PF01614: Bacterial transcriptional regulator NP_826319.1 PF05362: Lon protease (S16) C-terminal proteolytic domain NP_826326.1 ochronotic pigment biosynthesis, PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_826327.1 PF00515: TPR Domain NP_826328.1 similar to glycolate oxidase: PF01565: FAD binding domain NP_826329.1 PF06271: RDD family NP_826330.1 PF06271: RDD family NP_826332.1 PF05547: Immune inhibitor A peptidase M6 NP_826335.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_826336.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA NP_826339.1 PF01398: Mov34/MPN/PAD-1 family NP_826340.1 PF02597: ThiS family NP_826343.1 PF00753: Metallo-beta-lactamase superfamily NP_826344.1 PF02378: Phosphotransferase system, EIIC NP_826345.1 PF02378: Phosphotransferase system, EIIC NP_826346.1 PF00367: Phosphotransferase system, EIIB NP_826347.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_826349.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_826350.1 PF00561: alpha/beta hydrolase fold NP_826352.1 PF00083: Sugar (and other) transporter NP_826353.1 PF00578: AhpC/TSA family NP_826356.1 PF00912: Transglycosylase NP_826357.1 PF06182: Protein of unknown function (DUF990) NP_826358.1 PF06182: Protein of unknown function (DUF990) NP_826361.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_826362.1 PF04286: Protein of unknown function (DUF445) NP_826363.1 PF07690: Major Facilitator Superfamily NP_826370.1 PF03995: Peptidase inhibitor family I36 NP_826376.1 PF04149: Domain of unknown function (DUF397) NP_826378.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_826381.1 PF02810: SEC-C motif NP_826383.1 PF04203: Sortase family NP_826385.1 PF02096: 60Kd inner membrane protein NP_826387.1 PF06142: Protein of unknown function (DUF967) NP_826388.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_826393.1 PF04203: Sortase family NP_826395.1 PF07646: Kelch motif NP_826396.1 PF00535: Glycosyl transferase NP_826398.1 PF00877: NlpC/P60 family NP_826399.1 PF01145: SPFH domain / Band 7 family NP_826402.1 activates fatty acids by binding to coenzyme A NP_826411.1 PF01177: Asp/Glu/Hydantoin racemase NP_826412.1 PF01177: Asp/Glu/Hydantoin racemase NP_826413.1 PF00296: Luciferase-like monooxygenase NP_826414.1 PF00563: EAL domain NP_826418.1 PF00270: DEAD/DEAH box helicase NP_826423.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_826429.1 PF00553: Cellulose binding domain NP_826435.1 PF00583: Acetyltransferase (GNAT) family NP_826437.1 3'-5' exoribonuclease specific for small oligoribonuclotides NP_826439.1 PF07172: Glycine rich protein family NP_826440.1 PF00582: Universal stress protein family NP_826441.1 PF01184: GPR1/FUN34/yaaH family NP_826446.1 alcC, siderophore biosynthesis, PF04183: IucA / IucC family NP_826447.1 alcB, siderophore biosynthesis, PF00583: Acetyltransferase (GNAT) family NP_826448.1 alcA, siderophore biosynthesis NP_826449.1 rhbB, siderophore biosynthesis, PF00282: Pyridoxal-dependent decarboxylase conserved domain NP_826450.1 siderophore biosynthesis, PF04954: Siderophore-interacting protein NP_826451.1 siderophore biosynthesis NP_826452.1 acdH, PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_826457.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_826458.1 PF02551: Acyl-CoA thioesterase NP_826461.1 PF00474: Sodium:solute symporter family NP_826464.1 PF01839: FG-GAP repeat NP_826466.1 PF04231: Endonuclease I NP_826467.1 PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase NP_826469.1 PF01079: Hint module NP_826477.1 PF05576: PS-10 peptidase S37 NP_826481.1 PF00892: Integral membrane protein DUF6 NP_826484.1 PF05419: GUN4-like NP_826487.1 PF01261: AP endonuclease family 2 NP_826490.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_826491.1 PF06187: Protein of unknown function (DUF993) NP_826492.1 PF01261: AP endonuclease family 2 NP_826493.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source NP_826494.1 PF00294: pfkB family carbohydrate kinase NP_826495.1 D-ribose transport system NP_826496.1 D-ribose transport system NP_826497.1 transcriptional regulator mediating carbon catabolite repression NP_826506.1 PF05127: Putative ATPase (DUF699) NP_826507.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH NP_826508.1 PF00122: E1-E2 ATPase NP_826511.1 PF03176: MMPL family NP_826512.1 PF00107: Zinc-binding dehydrogenase NP_826514.1 inositol metaqbolism, PF06960: Myo-inositol catabolism protein N-terminus NP_826515.1 inositol metabolism, PF00294: pfkB family carbohydrate kinase NP_826516.1 PF04274: Tagatose 1,6-diphosphate aldolase, (LacD) NP_826517.1 inositol metabolism, PF06845: Myo-inositol catabolism protein IolB NP_826518.1 inositol metabolism, PF00205: Thiamine pyrophosphate enzyme, central domain NP_826520.1 PF00324: Amino acid permease NP_826528.1 PF00746: Gram positive anchor NP_826530.1 PF02706: Chain length determinant protein NP_826531.1 PF00534: Glycosyl transferases group 1 NP_826532.1 PF01522: Polysaccharide deacetylase NP_826533.1 PF03023: MviN-like protein NP_826534.1 PF04932: O-Antigen Polymerase NP_826535.1 PF02397: Bacterial sugar transferase NP_826536.1 PF00534: Glycosyl transferases group 1 NP_826538.1 second mel operon NP_826539.1 second mel operon, not form melanin NP_826543.1 PF05506: Domain of unknown function (DUF756) NP_826544.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence NP_826545.1 PF03061: Thioesterase superfamily NP_826547.1 PF01152: Bacterial-like globin NP_826549.1 PF00498: FHA domain NP_826550.1 PF00092: von Willebrand factor type A domain NP_826551.1 PF00481: Protein phosphatase 2C NP_826562.1 PF00924: Mechanosensitive ion channel NP_826564.1 PF02687: Predicted permease NP_826571.1 PF00892: Integral membrane protein DUF6 NP_826572.1 PF01433: Peptidase family M1 NP_826573.1 PF06718: Protein of unknown function (DUF1203) NP_826574.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_826577.1 PF00082: Subtilase family NP_826578.1 PF07336: Protein of unknown function (DUF1470) NP_826580.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_826581.1 PF00293: NUDIX domain NP_826582.1 PF00149: Calcineurin-like phosphoesterase NP_826583.1 PF01833: IPT/TIG domain NP_826584.1 PF04149: Domain of unknown function (DUF397) NP_826588.1 PF01433: Peptidase family M1 NP_826589.1 PF01323: DSBA-like thioredoxin domain NP_826590.1 Fe-containing superoxide dismutase NP_826592.1 PF02668: Taurine catabolism dioxygenase TauD, TfdA family NP_826596.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_826603.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_826604.1 involved in DNA repair; nick DNA at apurinic/apyrimidinic sites NP_826605.1 PF00583: Acetyltransferase (GNAT) family NP_826606.1 membrane protein NP_826612.1 PF03496: Clostridial binary toxin A NP_826615.1 PF01966: HD domain NP_826617.1 PF04600: Protein of unknown function (DUF571) NP_826618.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_826621.1 PF01757: acyltransferase family NP_826623.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_826624.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_826625.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_826626.1 binds and unfolds substrates as part of the ClpXP protease NP_826628.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_826631.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_826632.1 functions in MreBCD complex in some organisms NP_826633.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_826634.1 PF04093: rod shape-determining protein MreD NP_826635.1 PF00905: Penicillin binding protein transpeptidase domain NP_826636.1 PF01098: Cell cycle protein NP_826638.1 PF04055: radical SAM superfamily NP_826642.1 PF00575: S1 RNA binding domain NP_826645.1 involved in the peptidyltransferase reaction during translation NP_826646.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_826648.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_826650.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_826652.1 PF00866: Ring hydroxylating beta subunit NP_826653.1 PF01435: Peptidase family M48 NP_826655.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_826656.1 PF03816: Cell envelope-related transcriptional attenuator domain NP_826657.1 PF02410: Domain of unknown function DUF143 NP_826660.1 PF07690: Major Facilitator Superfamily NP_826663.1 PF01512: Respiratory-chain NADH dehydrogenase 51 Kd subunit NP_826665.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_826667.1 PF02645: Uncharacterized protein, DegV family COG1307 NP_826669.1 PF03772: Competence protein NP_826670.1 probably phage genome NP_826671.1 probably phage genome NP_826672.1 probably phage genome NP_826673.1 probably phage genome NP_826674.1 probably phage genome NP_826675.1 probably phage genome, similar to phage structural protein NP_826676.1 probably phage genome NP_826677.1 probably phage genome NP_826678.1 probably phage genome NP_826679.1 probably phage genome NP_826680.1 probably phage genome NP_826681.1 probably phage genome NP_826682.1 probably phage genome, similar to phage structure protein NP_826683.1 probably phage genome NP_826684.1 probably phage genome NP_826685.1 probably phage genome, similar to phage tail protein NP_826686.1 probably phage genome NP_826687.1 probably phage genome NP_826688.1 probably phage genome, similar to phage structure protein NP_826689.1 probably phage genome NP_826690.1 probably phage genome NP_826691.1 probably phage genome NP_826692.1 probably phage genome NP_826693.1 probably phage genome NP_826694.1 probably phage genome NP_826695.1 probably phage genome NP_826696.1 probably phage genome, PF06810: Phage minor structural protein GP20 NP_826697.1 probably phage genome, PF05126: Phage minor capsid protein NP_826698.1 probably phage genome, PF03237: Protein of unknown function DUF264 NP_826699.1 probably phage genome, PF00196: Bacterial regulatory proteins, luxR family NP_826700.1 probably phage genome NP_826701.1 probably phage genome NP_826702.1 probably phage genome, PF00376: MerR family regulatory protein NP_826703.1 probably phage genome, PF03536: Salmonella virulence-associated 28kDa protein NP_826704.1 probably phage genome NP_826705.1 probably phage genome NP_826706.1 probably phage genome NP_826707.1 probably phage genome NP_826708.1 probably phage genome, PF05992: SbmA/BacA-like family NP_826709.1 probably phage genome NP_826710.1 probably phage genome NP_826711.1 probably phage genome NP_826712.1 probably phage genome NP_826713.1 probably phage genome, PF00145: C-5 cytosine-specific DNA methylase NP_826714.1 probably phage genome NP_826715.1 probably phage genome NP_826716.1 probably phage genome NP_826717.1 probably phage genome, PF02498: BRO family, N-terminal domain NP_826718.1 probably phage genome NP_826719.1 probably phage genome NP_826720.1 probably phage genome NP_826721.1 probably phage genome NP_826722.1 probably phage genome NP_826723.1 probably phage genome NP_826724.1 probably phage genome NP_826725.1 probably phage genome, PF07508: Recombinase NP_826726.1 probably phage genome NP_826727.1 probably phage genome, PF04149: Domain of unknown function (DUF397) NP_826728.1 probably phage genome, PF06036: Streptomyces protein of unknown function (DUF921) NP_826729.1 probably phage genome NP_826730.1 probably phage genome NP_826731.1 probably phage genome NP_826732.1 probably phage genome, PF07508: Recombinase NP_826733.1 PF00797: N-acetyltransferase NP_826737.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_826738.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_826739.1 PF00501: AMP-binding enzyme NP_826742.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_826743.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_826745.1 PF00753: Metallo-beta-lactamase superfamily NP_826746.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_826747.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_826748.1 PF03060: 2-nitropropane dioxygenase NP_826749.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_826751.1 PF03572: Peptidase family S41 NP_826752.1 PF01230: HIT domain NP_826753.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions NP_826754.1 catalyzes the formation of inosine from adenosine NP_826755.1 PF07690: Major Facilitator Superfamily NP_826757.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate NP_826761.1 PF02130: Uncharacterized protein family UPF0054 NP_826762.1 PF00571: CBS domain NP_826763.1 PF04237: Protein of unknown function (DUF419) NP_826764.1 PF07690: Major Facilitator Superfamily NP_826770.1 regulatory protein for glutamine synthetase; glnB-homolog NP_826772.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_826773.1 PF00583: Acetyltransferase (GNAT) family NP_826774.1 PF07690: Major Facilitator Superfamily NP_826777.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_826780.1 PF03176: MMPL family NP_826802.1 PF04149: Domain of unknown function (DUF397) NP_826805.2 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_826807.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_826812.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_826814.1 PF00248: Aldo/keto reductase family NP_826816.1 PF04672: Protein of unknown function (DUF574) NP_826823.1 PF07690: Major Facilitator Superfamily NP_826825.1 PF07690: Major Facilitator Superfamily NP_826827.1 PF00884: Sulfatase NP_826829.1 PF06202: Amylo-alpha-1,6-glucosidase NP_826831.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_826835.1 PF00916: Sulfate transporter family NP_826836.1 PF00106: short chain dehydrogenase NP_826839.1 PF01925: Domain of unknown function DUF81 NP_826840.1 PF04203: sortase family NP_826843.1 PF04264: YceI like family NP_826845.1 PF00561: alpha/beta hydrolase fold NP_826846.1 PF02868: Thermolysin metallopeptidase, alpha-helical domain NP_826847.1 PF03674: Uncharacterised protein family (UPF0131) NP_826848.1 PF00775: Dioxygenase NP_826849.1 probable vancomycin sensitivity, PF02698: DUF218 domain NP_826850.1 PF01903: CbiX NP_826851.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate NP_826853.1 synthesizes RNA primers at the replication forks NP_826856.1 sigma-70 family NP_826871.1 PF01850: PIN domain NP_826872.1 PF00350: Dynamin family NP_826873.1 PF00350: Dynamin family NP_826883.1 PF03992: Antibiotic biosynthesis monooxygenase NP_826886.1 PF00082: Subtilase family NP_826887.1 PF00156: Phosphoribosyl transferase domain NP_826888.1 PF00561: alpha/beta hydrolase fold NP_826892.1 PF04055: Radical SAM superfamily NP_826897.1 PF06723: MreB/Mbl protein NP_826898.1 PF00082: Subtilase family NP_826900.1 activates fatty acids by binding to coenzyme A NP_826903.1 PF00190: Cupin NP_826904.1 PF00376: MerR family regulatory protein, PF00481: Protein phosphatase 2C NP_826908.1 PF03966: Protein of unknown function (DUF343) NP_826910.1 PF05401: Nodulation protein S (NodS) NP_826911.1 PF00668: Condensation domain NP_826912.1 PF00754: F5/8 type C domain NP_826914.1 PF00534: Glycosyl transferases group 1 NP_826921.1 PF01833: IPT/TIG domain NP_826930.1 PF04149: Domain of unknown function (DUF397) NP_826935.1 PF00775: Dioxygenase NP_826936.1 PF01360: Monooxygenase NP_826938.1 PF00775: Dioxygenase NP_826941.1 PF00144: Beta-lactamase NP_826948.1 PF00107: Zinc-binding dehydrogenase NP_826953.1 PF00107: Zinc-binding dehydrogenase NP_826957.1 PF04401: Protein of unknown function (DUF540) NP_826958.1 PF01470: Pyroglutamyl peptidase NP_826960.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_826962.1 PF00109: Beta-ketoacyl synthase, N-terminal domain NP_826963.1 carries the fatty acid chain in fatty acid biosynthesis NP_826964.1 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis NP_826965.1 PF00698: Acyl transferase domain NP_826967.1 PF02678: Pirin NP_826968.1 PF00144: Beta-lactamase NP_826970.1 PF00248: Aldo/keto reductase family NP_826972.1 PF06259: Domain of unknown function (DUF1023) NP_826974.1 PF07690: Major Facilitator Superfamily NP_826976.1 PF00520: Ion transport protein NP_826977.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC NP_826980.1 PF02342: Bacterial stress protein NP_826981.1 PF02342: Bacterial stress protein NP_826982.1 PF04332: Protein of unknown function (DUF475) NP_826983.1 PF02342: Bacterial stress protein NP_826984.1 PF02342: Bacterial stress protein NP_826990.1 PF01442: Apolipoprotein A1/A4/E family NP_826992.1 PF00589: Phage integrase family NP_826996.1 PF02558: Ketopantoate reductase PanE/ApbA NP_827000.1 PF00597: DedA family NP_827001.1 PF07681: DoxX NP_827005.1 PF01169: Uncharacterized protein family UPF0016 NP_827006.1 PF00702: haloacid dehalogenase-like hydrolase NP_827007.1 PF01471: Putative peptidoglycan binding domain NP_827008.1 PF07690: Major Facilitator Superfamily NP_827009.1 PF00583: Acetyltransferase (GNAT) family NP_827016.1 PF00083: Sugar (and other) transporter NP_827018.1 CYP125A2, fadA7 is located at upstream NP_827019.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_827020.1 PF06912: Protein of unknown function (DUF1275) NP_827021.1 PF03583: Secretory lipase NP_827022.1 PF06737: Transglycosylase-like domain NP_827025.1 PF02361: Cobalt transport protein NP_827027.1 PF00432: Prenyltransferase and squalene oxidase repeat NP_827028.1 PF00753: Metallo-beta-lactamase superfamily NP_827029.1 PF00171: Aldehyde dehydrogenase family NP_827032.1 PF00534: Glycosyl transferases group 1 NP_827038.1 PF01520: N-acetylmuramoyl-L-alanine amidase NP_827041.1 PF00296: Luciferase-like monooxygenase NP_827042.1 PF07690: Major Facilitator Superfamily NP_827044.1 PF07690: Major Facilitator Superfamily NP_827048.1 PF00107: Zinc-binding dehydrogenase NP_827049.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_827052.1 PF01784: NIF3 (NGG1p interacting factor 3) NP_827053.1 PF02591: Uncharacterized ACR, COG1579 NP_827056.1 PF03883: Protein of unknown function (DUF328) NP_827057.1 PF00773: RNB-like protein NP_827059.1 PF00892: Integral membrane protein DUF6 NP_827064.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_827067.1 PF04672: Protein of unknown function (DUF574) NP_827068.1 PF05079: Protein of unknown function (DUF680) NP_827071.1 mceF, PF02470: mce related protein NP_827072.1 mceE, PF02470: mce related protein NP_827073.1 mceD, PF02470: mce related protein NP_827074.1 mceC, PF02470: mce related protein NP_827075.1 mceB, PF02470: mce related protein NP_827076.1 mceA, PF02470: mce related protein NP_827081.1 PF01464: Transglycosylase SLT domain NP_827085.1 PF03819: MazG nucleotide pyrophosphohydrolase domain NP_827086.1 PF07681: DoxX NP_827089.1 PF02687: Predicted permease NP_827090.1 PF00768: D-alanyl-D-alanine carboxypeptidase NP_827091.1 PF00106: short chain dehydrogenase NP_827093.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_827094.1 PF07690: Major Facilitator Superfamily NP_827095.1 PF00144: Beta-lactamase NP_827101.1 PF03239: Iron permease FTR1 family NP_827102.1 This family of dye-decolourising peroxidases lack a typical heme-binding region NP_827103.1 PF04302: Protein of unknown function (DUF451) NP_827106.1 PF02567: phenazine biosynthesis-like protein NP_827108.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_827112.1 PF03807: NADP oxidoreductase coenzyme F420-dependent NP_827114.1 PF02163: Peptidase family M50 NP_827120.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_827121.1 PF07690: Major Facilitator Superfamily NP_827123.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_827124.1 similar to cmlR, PF07690: Major Facilitator Superfamily NP_827126.1 PF00082: Subtilase family NP_827127.1 PF03713: Domain of unknown function (DUF305) NP_827129.1 PF02082: Transcriptional regulator NP_827139.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_827142.1 PF01738: Dienelactone hydrolase family NP_827143.1 PF04149: Domain of unknown function (DUF397) NP_827147.1 PF07690: Major Facilitator Superfamily NP_827149.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme NP_827150.1 PF00892: Integral membrane protein DUF6 NP_827153.1 LacI-family transcriptional regulator NP_827154.1 ABC transporter substrate-binding protein NP_827155.1 ABC transporter permease NP_827156.1 ABC transporter permease NP_827160.1 PF00072: Response regulator receiver domain NP_827178.1 PF01636: Phosphotransferase enzyme family NP_827180.1 putative metalloprotease NP_827183.1 PF06271: RDD family NP_827186.1 catalyzes the radical-mediated insertion of two sulfur atoms into an ACP ACP bound to an octanoyl group to produce a lipoyl group NP_827187.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism NP_827189.1 PF01593: Flavin containing amine oxidoreductase NP_827191.1 PF00583: Acetyltransferase (GNAT) family NP_827192.1 PF00089: Trypsin NP_827193.1 PF01510: N-acetylmuramoyl-L-alanine amidase NP_827197.1 paralogs to the E1 component of pyruvate dehydrogenase subunit E1 NP_827200.2 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_827201.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_827202.1 cobalamin biosynthesis NP_827203.1 PF00499: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NP_827205.1 PF04329: Family of unknown function (DUF470) NP_827206.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole NP_827208.1 cobalamin biosynthesis NP_827216.1 involving efflux of acriflavin-related compounds, PF00873: AcrB/AcrD/AcrF family NP_827217.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_827218.1 PF01521: HesB-like domain NP_827219.1 PF04886: PT repeat NP_827226.1 PF03734: ErfK/YbiS/YcfS/YnhG NP_827232.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_827235.1 PF01694: Rhomboid family NP_827237.1 PF05991: Protein of unknown function (DUF901) NP_827243.1 PF00534: Glycosyl transferases group 1 NP_827244.1 PF05199: GMC oxidoreductase NP_827245.1 PF00501: AMP-binding enzyme NP_827246.1 PF00149: Calcineurin-like phosphoesterase NP_827248.1 PF02374: Anion-transporting ATPase NP_827251.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_827259.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_827262.1 EC:2.5.1.54, DAHP synthase NP_827263.1 PF04324: BFD-like [2Fe-2S] binding domain NP_827265.1 PF00174: Oxidoreductase molybdopterin binding domain NP_827269.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_827270.1 PF02597: ThiS family NP_827275.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_827281.1 PF01061: ABC-2 type transporter NP_827286.1 PF01841: Transglutaminase-like superfamily NP_827287.1 PF01882: Protein of unknown function DUF58 NP_827291.1 PF04977: Septum formation initiator NP_827292.1 PF00905: Penicillin binding protein transpeptidase domain NP_827293.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_827295.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_827296.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_827297.1 PF01098: Cell cycle protein NP_827298.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_827300.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_827301.1 PF02578: Uncharacterised ACR, YfiH family COG1496 NP_827302.1 PF01168: Alanine racemase, N-terminal domain NP_827303.1 PF04472: Protein of unknown function (DUF552) NP_827304.1 PF02325: YGGT family NP_827305.1 PF05103: DivIVA protein NP_827306.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_827308.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_827311.1 PF00999: Sodium/hydrogen exchanger family NP_827312.1 PF00106: short chain dehydrogenase NP_827313.1 PF00924: Mechanosensitive ion channel NP_827314.1 PF01738: Dienelactone hydrolase family NP_827316.1 PF01323: DSBA-like thioredoxin domain NP_827319.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_827321.1 PF01936: Protein of unknown function DUF88 NP_827326.1 PF02190: ATP-dependent protease La (LON) domain NP_827329.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_827330.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_827331.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_827333.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_827334.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis NP_827335.1 PF01042: Endoribonuclease L-PSP NP_827336.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_827338.1 PF07690: Major Facilitator Superfamily NP_827344.1 PF01094: Receptor family ligand binding region NP_827345.1 PF07398: Protein of unknown function (DUF1503) NP_827346.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers NP_827347.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_827351.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water NP_827353.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_827354.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_827355.1 PF01323: DSBA-like thioredoxin domain NP_827356.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_827359.1 PF03747: ADP-ribosylglycohydrolase NP_827360.1 PF03747: ADP-ribosylglycohydrolase NP_827361.1 frameshift NP_827362.1 frameshift NP_827363.1 PF03747: ADP-ribosylglycohydrolase NP_827364.1 PF01988: Integral membrane protein DUF125 NP_827366.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_827367.1 PF01374: Glycosyl hydrolase family 46 NP_827368.1 PF01694: Rhomboid family NP_827370.1 PF05962: Bacterial protein of unknown function (DUF886) NP_827371.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_827372.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_827373.1 PF00106: short chain dehydrogenase NP_827375.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_827376.1 NADH-dependent, FAD-containing enoyl-ACP reductase, PF03060: 2-nitropropane dioxygenase NP_827379.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_827380.1 PF00106: short chain dehydrogenase NP_827381.1 PF00106: short chain dehydrogenase NP_827382.1 PF00023: Ankyrin repeat NP_827385.1 PF00583: Acetyltransferase (GNAT) family NP_827386.1 catalyzes the interconversion of chorismate to prephenate NP_827388.1 PF01433: Peptidase family M1 NP_827390.1 PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_827392.1 PF04402: Protein of unknown function (DUF541) NP_827400.1 ABC transporter periplasmic component NP_827401.1 PF03061: Thioesterase superfamily NP_827403.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_827404.1 PF04307: Predicted membrane-bound metal-dependent hydrolase (DUF457) NP_827405.1 PF01464: Transglycosylase SLT domain NP_827407.1 PF04408: Helicase associated domain (HA2) NP_827409.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_827410.1 PF05601: Protein of unknown function (DUF774) NP_827412.1 PF00515: TPR Domain NP_827416.1 PF07681: DoxX NP_827417.1 PF01479: S4 domain NP_827418.1 PF03167: Uracil DNA glycosylase superfamily NP_827420.1 PF01042: Endoribonuclease L-PSP NP_827424.1 PF05976: Bacterial membrane protein of unknown function (DUF893) NP_827425.1 CYP107X1 NP_827430.1 regulatory protein NP_827431.1 PF04672: Protein of unknown function (DUF574) NP_827433.1 PF02627: Carboxymuconolactone decarboxylase family NP_827434.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain NP_827436.1 PF00643: B-box zinc finger NP_827438.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_827439.1 PF00571: CBS domain NP_827443.1 uncharacterized enzyme involved in pigment biosynthesis, PF04227: Indigoidine synthase A like protein NP_827444.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_827445.1 PF05899: Protein of unknown function (DUF861) NP_827448.1 PF03707: Bacterial signalling protein N terminal repeat NP_827449.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_827450.1 PF02342: Bacterial stress protein NP_827451.1 PF02342: Bacterial stress protein NP_827452.1 PF03741: Integral membrane protein TerC family NP_827453.1 PF01699: Sodium/calcium exchanger protein NP_827454.1 PF00083: Sugar (and other) transporter NP_827455.1 PF02016: LD-carboxypeptidase NP_827456.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_827460.1 PF00753: Metallo-beta-lactamase superfamily NP_827461.1 in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol NP_827462.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_827467.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_827468.1 PF03668: P-loop ATPase protein family NP_827469.1 PF01933: Uncharacterised protein family UPF0052 NP_827471.1 PF00246: Zinc carboxypeptidase NP_827473.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_827474.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_827475.1 PF03840: Preprotein translocase SecG subunit NP_827477.1 PF07690: Major Facilitator Superfamily NP_827478.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_827487.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone NP_827489.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_827490.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate NP_827491.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_827492.1 converts protoheme IX and farnesyl diphosphate to heme O NP_827494.1 PF04909: Amidohydrolase NP_827495.1 PF01909: Nucleotidyltransferase domain NP_827496.1 PF02628: Cytochrome oxidase assembly protein NP_827503.1 PF00355: Rieske [2Fe-2S] domain NP_827507.1 PF01883: Domain of unknown function DUF59 NP_827519.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_827521.1 PF07332: Protein of unknown function (DUF1469) NP_827523.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_827525.1 PF05787: Bacterial protein of unknown function (DUF839) NP_827526.1 PF05731: TROVE domain NP_827527.1 PF07690: Major Facilitator Superfamily NP_827529.1 PF02342: Bacterial stress protein NP_827530.1 PF00107: Zinc-binding dehydrogenase NP_827531.1 maltose/mannitol transport protein NP_827532.1 maltose/mannitol transport protein NP_827533.1 maltose/mannitol transport protein NP_827535.1 PF01370: NAD dependent epimerase/dehydratase family NP_827536.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate NP_827538.1 PF07690: Major Facilitator Superfamily NP_827540.1 PF00753: Metallo-beta-lactamase superfamily NP_827543.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate NP_827546.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_827549.1 PF00497: Bacterial extracellular solute-binding proteins, family 3 NP_827550.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_827563.1 PF00905: Penicillin binding protein transpeptidase domain NP_827566.1 PF07081: Protein of unknown function (DUF1349) NP_827567.1 PF07690: Major Facilitator Superfamily NP_827569.1 PF01323: DSBA-like thioredoxin domain NP_827570.1 PF00266: Aminotransferase class-V NP_827571.1 ectoine cluster, PF05721: Phytanoyl-CoA dioxygenase (PhyH) NP_827572.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid NP_827573.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde NP_827574.1 ectoine cluster, PF00583: Acetyltransferase (GNAT) family NP_827575.1 aminotransferase class-V NP_827579.1 PF01979: Amidohydrolase family NP_827580.1 cobalamin biosynthesis NP_827581.1 cobalamin biosynthesis (other possible function is involved in expression of nickel-containing superoxide dismutase) NP_827582.1 cobalamin biosynthesis NP_827583.1 CbiG/H-fusion; cobalamin biosynthesis NP_827584.1 cobalamin biosynthesis NP_827585.1 cobalamin biosynthesis NP_827587.1 cobalamin biosynthesis NP_827588.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid NP_827589.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide NP_827590.1 cobalamin biosynthesis porphyrin-related NP_827591.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism NP_827592.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation NP_827593.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group NP_827596.1 PF01183: Glycosyl hydrolases family 25 NP_827598.1 PF00326: Prolyl oligopeptidase family NP_827600.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_827606.1 PF03780: Protein of unknown function (DUF322) NP_827608.1 PF03780: Protein of unknown function (DUF322) NP_827611.1 PF00106: short chain dehydrogenase NP_827612.1 PF00723: Glycosyl hydrolases family 15 NP_827615.1 3'-5' exonuclease of DNA polymerase III NP_827617.1 PF06314: Acetoacetate decarboxylase (ADC) NP_827618.1 probable dehydrogenase NP_827619.1 PF04909: Amidohydrolase NP_827620.1 PF04909: Amidohydrolase NP_827621.1 PF01988: Integral membrane protein DUF125 NP_827622.1 PF01598: Sterol desaturase NP_827624.1 PF00107: Zinc-binding dehydrogenase NP_827625.1 PF05425: Copper resistance protein D NP_827626.1 PF02515: CoA-transferase family III NP_827627.1 PF00082: Subtilase family NP_827628.1 PF00082: Subtilase family NP_827629.1 PF04341: Protein of unknown function, DUF485 NP_827630.1 PF00474: Sodium:solute symporter family NP_827631.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_827636.1 PF01523: Putative modulator of DNA gyrase NP_827637.1 PF01523: Putative modulator of DNA gyrase NP_827638.1 PF00106: short chain dehydrogenase NP_827639.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_827642.1 PF07690: Major Facilitator Superfamily NP_827645.1 PF00300: Phosphoglycerate mutase family NP_827649.1 PF01464: Transglycosylase SLT domain NP_827651.1 PF00106: short chain dehydrogenase NP_827654.1 PF03777: Small domain (DUF320) NP_827658.1 PF01145: SPFH domain / Band 7 family NP_827659.1 PF01844: HNH endonuclease NP_827661.1 PF07070: SpoOM protein NP_827662.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair NP_827665.1 PF06245: Protein of unknown function (DUF1015) NP_827666.1 PF00702: haloacid dehalogenase-like hydrolase NP_827667.1 iron-siderophore uptake system transmembrane component NP_827668.1 iron-siderophore uptake system transmembrane component NP_827669.1 iron-siderophore uptake system transmembrane component NP_827672.1 PF01479: S4 domain, PF01728: FtsJ-like methyltransferase NP_827673.1 catalyzes the phosphorylation of NAD to NADP NP_827674.1 PF02687: Predicted permease NP_827675.1 PF02483: SMC family, C-terminal domain NP_827677.1 PF00534: Glycosyl transferases group 1 NP_827679.1 PF00723: Glycosyl hydrolases family 15 NP_827680.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_827684.1 PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain NP_827686.1 PF02616: Uncharacterised ACR, COG1354 NP_827689.1 PF00293: NUDIX domain NP_827696.1 EC:5.4.99.5 NP_827697.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_827698.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_827700.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_827703.1 PF06737: Transglycosylase-like domain NP_827704.1 PF06737: Transglycosylase-like domain NP_827710.1 PF00534: Glycosyl transferases group 1 NP_827713.1 EC 1.9.3.1 NP_827715.1 PF01569: PAP2 superfamily NP_827716.1 PF04188: Protein of unknown function (DUF409) NP_827717.1 PF07690: Major Facilitator Superfamily NP_827718.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_827719.1 PF04472: Protein of unknown function (DUF552) NP_827728.1 PF02983: Alpha-lytic protease prodomain NP_827729.1 PF02983: Alpha-lytic protease prodomain NP_827732.1 PF00817: impB/mucB/samB family NP_827733.1 PF00190: Cupin NP_827737.1 PF00583: Acetyltransferase (GNAT) family NP_827739.1 PF01209: ubiE/COQ5 methyltransferase family NP_827740.1 PF04167: Protein of unknown function (DUF402) NP_827741.1 PF00583: Acetyltransferase (GNAT) family NP_827743.1 PF01904: Protein of unknown function DUF72 NP_827744.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_827746.1 PF01554: MatE NP_827747.1 PF01522: Polysaccharide deacetylase NP_827752.1 PF00082: Subtilase family NP_827753.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_827755.1 PF03824: High-affinity nickel-transport protein NP_827756.1 PF00515: TPR Domain NP_827758.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins NP_827762.1 PF07702: UbiC transcription regulator-associated NP_827763.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine NP_827766.1 PF00384: Molybdopterin oxidoreductase NP_827767.1 PF03600: Citrate transporter NP_827768.1 PF07690: Major Facilitator Superfamily NP_827770.1 PF04203: Sortase family NP_827771.1 PF00171: Aldehyde dehydrogenase family NP_827772.1 PF00107: Zinc-binding dehydrogenase NP_827773.1 PF00892: Integral membrane protein DUF6 NP_827776.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_827779.1 PF01575: MaoC like domain NP_827781.1 PF01588: Putative tRNA binding domain NP_827784.1 PF01804: Penicillin amidase NP_827785.1 PF05990: Protein of unknown function (DUF900) NP_827786.1 PF07075: Protein of unknown function (DUF1343) NP_827787.1 PF00106: short chain dehydrogenase NP_827788.1 PF00501: AMP-binding enzyme NP_827790.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_827792.1 similar to actIV cyclase NP_827794.1 PF02656: Domain of unknown function DUF NP_827795.1 PF00293: NUDIX domain NP_827796.1 PF05653: Protein of unknown function (DUF803) NP_827797.1 proposed role in polysaccahride synthesis NP_827799.1 PF00324: Amino acid permease NP_827800.1 PF00174: Oxidoreductase molybdopterin binding domain NP_827802.1 PF00107: Zinc-binding dehydrogenase NP_827806.1 nrps5 gene cluster NP_827807.1 nrps5 gene cluster, PF02810: SEC-C motif NP_827808.1 nrps5 gene cluster, PF01433: Peptidase family M1 NP_827809.1 nrps5 gene cluster NP_827810.1 PF01546: Peptidase family M20/M25/M40 NP_827811.1 PF03777: Small domain (DUF320) NP_827812.1 PF03777: Small domain (DUF320) NP_827816.1 PF00248: Aldo/keto reductase family NP_827817.1 PF00296: Luciferase-like monooxygenase NP_827819.1 PF01544: CorA-like Mg2+ transporter protein NP_827820.1 PF00300: Phosphoglycerate mutase family NP_827823.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_827825.1 PF00082: Subtilase family NP_827826.1 PF05601: Protein of unknown function (DUF774) NP_827828.1 PF01979: Amidohydrolase family NP_827833.1 PF02608: Basic membrane protein NP_827836.1 PF00702: haloacid dehalogenase-like hydrolase NP_827844.1 PF00702: haloacid dehalogenase-like hydrolase NP_827845.1 PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle NP_827846.1 PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle NP_827849.1 PF02163: Peptidase family M50 NP_827853.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_827854.1 PF03136: Putative proteasome component NP_827855.1 PF05639: Protein of unknown function (DUF797) NP_827857.1 PF00227: Proteasome A-type and B-type NP_827858.1 PF00227: Proteasome A-type and B-type NP_827860.1 PF07690: Major Facilitator Superfamily NP_827861.1 PF03136: Putative proteasome component NP_827868.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes NP_827869.1 PF00902: Sec-independent protein translocase protein (TatC) NP_827870.1 PF00781: Diacylglycerol kinase catalytic domain (presumed) NP_827871.1 PF00270: DEAD/DEAH box helicase NP_827872.1 PF00296: Luciferase-like monooxygenase NP_827873.1 catalyzes the hydrolysis of allophanate NP_827878.1 multi-component regulatory system-10 NP_827879.1 multi-component regulatory system-10, PF03259: Roadblock/LC7 domain NP_827880.1 multi-component regulatory system-10, PF05331: Protein of unknown function (DUF742) NP_827881.1 multi-component regulatory system-10 NP_827882.1 CYP157C2, adjacent to multi-component regulatory system-10 NP_827884.1 PF00583: Acetyltransferase (GNAT) family NP_827889.1 PF04954: Siderophore-interacting protein NP_827896.1 PF01497: Periplasmic binding protein NP_827897.1 PF03595: C4-dicarboxylate transporter/malic acid transport protein NP_827899.1 PF00117: Glutamine amidotransferase class-I NP_827903.1 PF00106: short chain dehydrogenase NP_827906.1 PF01168: Alanine racemase, N-terminal domain NP_827909.1 PF00082: Subtilase family NP_827913.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_827915.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_827916.1 PF00588: SpoU rRNA Methylase family NP_827918.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_827919.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_827920.1 PF02673: Bacitracin resistance protein BacA NP_827921.1 PF06036: Streptomyces protein of unknown function (DUF921) NP_827922.1 PF00293: NUDIX domain NP_827924.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA NP_827925.1 PF02638: Uncharacterized BCR, COG1649 NP_827927.1 PF00892: Integral membrane protein DUF6 NP_827929.1 PF00583: Acetyltransferase (GNAT) family NP_827930.1 PF00300: Phosphoglycerate mutase family NP_827939.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_827940.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_827941.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_827942.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine NP_827943.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_827945.1 PF04205: FMN-binding domain NP_827946.1 PF00175: Oxidoreductase NAD-binding domain NP_827947.1 PF04205: FMN-binding domain NP_827948.1 PF00175: Oxidoreductase NAD-binding domain NP_827952.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_827954.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_827955.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_827956.1 PF00248: Aldo/keto reductase family NP_827958.1 PF07690: Major Facilitator Superfamily NP_827962.1 PF00583: Acetyltransferase (GNAT) family NP_827969.1 PF00583: Acetyltransferase (GNAT) family NP_827970.1 cobalamin biosynthesis NP_827971.1 cobalamin biosynthesis NP_827977.1 PF01636: Phosphotransferase enzyme family NP_827979.1 PF00425: chorismate binding enzyme NP_827980.1 PF01063: Aminotransferase class IV NP_827981.1 PF00583: Acetyltransferase (GNAT) family NP_827982.1 PF01323: DSBA-like thioredoxin domain NP_827985.1 PF07336: Protein of unknown function (DUF1470) NP_827986.1 PF04686: Streptomyces sporulation and cell division protein, SsgA NP_827993.1 PF01970: Integral membrane protein DUF112 NP_827994.1 PF03364: Streptomyces cyclase/dehydrase NP_827995.1 3'-5' exonuclease of DNA polymerase III NP_827998.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_828001.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_828002.1 PF01066: CDP-alcohol phosphatidyltransferase NP_828003.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA NP_828006.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_828007.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate NP_828008.1 PF01709: Domain of unknown function DUF28 NP_828009.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_828010.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_828011.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_828012.1 PF02699: Preprotein translocase subunit NP_828013.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_828014.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_828015.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_828016.1 PF04607: Region found in RelA / SpoT proteins NP_828017.1 PF03993: Domain of Unknown Function (DUF349) NP_828019.1 PF00753: Metallo-beta-lactamase superfamily NP_828020.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_828023.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_828024.1 PF05962: Bacterial protein of unknown function (DUF886) NP_828026.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_828027.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_828028.1 PF02618: Aminodeoxychorismate lyase, a pyridoxal 5'-phosphate-dependent enzyme that converts 4-aminodeoxychorismate to pyruvate and p-aminobenzoate NP_828029.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_828030.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_828031.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_828032.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_828034.1 PF00557: metallopeptidase family M24 NP_828035.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_828036.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_828038.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_828039.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_828040.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_828042.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_828043.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_828044.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors NP_828045.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_828047.1 Essential for recycling GMP and indirectly, cGMP NP_828048.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_828049.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine NP_828050.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_828051.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_828053.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_828054.1 PF01189: NOL1/NOP2/sun family NP_828055.1 similar to actII-3, PF03176: MMPL family NP_828056.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_828058.1 PF00545: ribonuclease NP_828060.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_828061.1 PF00583: Acetyltransferase (GNAT) family NP_828066.1 PF03259: Roadblock/LC7 domain NP_828067.1 PF05331: Protein of unknown function (DUF742) NP_828068.1 PF00795: Carbon-nitrogen hydrolase NP_828070.1 PF00296: Luciferase-like monooxygenase NP_828075.1 PF03061: Thioesterase superfamily NP_828076.1 PF07690: Major Facilitator Superfamily NP_828078.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_828079.1 PF04973: Nicotinamide mononucleotide transporter NP_828080.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_828081.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_828082.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis NP_828083.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors NP_828085.1 PF01595: Domain of unknown function DUF21, PF03471: Transporter associated domain, PF00571: CBS domain NP_828086.1 PF01595: Domain of unknown function DUF21 NP_828087.1 PF00004: ATPase family associated with various cellular activities (AAA) NP_828088.1 PF00485: Phosphoribulokinase / Uridine kinase family NP_828095.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_828099.1 PF00535: Glycosyl transferase NP_828100.1 PF04186: FxsA cytoplasmic membrane protein NP_828102.1 PF07690: Major Facilitator Superfamily NP_828104.1 PF02588: Uncharacterized BCR, YitT family COG1284 NP_828105.1 similar to PdxR involved in regulation of pyridoxal phosphate NP_828106.1 PF01580: FtsK/SpoIIIE family NP_828108.1 PF00023: Ankyrin repeat NP_828110.1 PF00534: Glycosyl transferases group 1 NP_828111.1 PF00534: Glycosyl transferases group 1 NP_828112.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_828116.1 PF07286: Protein of unknown function (DUF1445) NP_828117.1 PF07690: Major Facilitator Superfamily NP_828121.1 PF01576: Myosin tail NP_828122.1 PF00732: GMC oxidoreductase NP_828125.1 PF00355: Rieske [2Fe-2S] domain NP_828126.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids NP_828127.1 PF01571: Glycine cleavage T-protein (aminomethyl transferase) NP_828128.1 PF00753: Metallo-beta-lactamase superfamily NP_828129.1 PF00107: Zinc-binding dehydrogenase NP_828134.1 multi-component regulatory system-11 NP_828135.1 multi-component regulatory system-11, PF03259: Roadblock/LC7 domain NP_828136.1 multi-component regulatory system-11, PF05331: Protein of unknown function (DUF742) NP_828137.1 PF02538: Hydantoinase B/oxoprolinase NP_828138.1 multi-component regulatory system-11 NP_828141.1 PF00563: EAL domain NP_828142.1 PF00108: Thiolase, N-terminal domain NP_828143.1 PF01796: Domain of unknown function DUF35 NP_828145.1 PF01055: Glycosyl hydrolases family 31 NP_828146.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase NP_828148.1 PF07690: Major Facilitator Superfamily NP_828150.1 PF02896: PEP-utilising enzyme, TIM barrel domain NP_828151.1 PF00358: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NP_828154.1 PF05949: Bacterial protein of unknown function (DUF881) NP_828155.1 PF06947: Protein of unknown function (DUF1290) NP_828156.1 PF05949: Bacterial protein of unknown function (DUF881) NP_828157.1 PF00498: FHA domain NP_828158.1 PF00376: MerR family regulatory protein NP_828159.1 PF02577: Uncharacterised ACR, COG1259 NP_828161.1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits NP_828162.1 PF05239: PRC-barrel domain NP_828163.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine NP_828166.1 PF04107: Glutamate-cysteine ligase family 2(GCS2) NP_828167.1 PF00092: von Willebrand factor type A domain NP_828168.1 PF02517: CAAX amino terminal protease family NP_828169.1 PF02567: Phenazine biosynthesis-like protein NP_828171.1 PF03364: Streptomyces cyclase/dehydrase NP_828172.1 PF02861: Clp amino terminal domain NP_828173.1 PF00892: Integral membrane protein DUF6 NP_828174.1 PF00892: Integral membrane protein DUF6 NP_828177.1 PF00892: Integral membrane protein DUF6 NP_828179.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_828180.1 PF00857: Isochorismatase family NP_828184.1 PF00106: short chain dehydrogenase NP_828185.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_828186.1 PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle NP_828187.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_828190.1 PF04978: Protein of unknown function (DUF664) NP_828191.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_828192.1 PF00795: Carbon-nitrogen hydrolase NP_828194.1 PF00296: Luciferase-like monooxygenase NP_828195.1 PF03631: Ribonuclease BN-like family NP_828197.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell NP_828198.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_828202.1 PF00108: Thiolase, N-terminal domain NP_828203.1 PF00597: DedA family NP_828204.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_828206.1 PF07690: Major Facilitator Superfamily NP_828210.1 PF05257: CHAP domain NP_828211.1 PF00474: Sodium:solute symporter family NP_828212.1 PF04341: Protein of unknown function, DUF485 NP_828213.1 PF00597: DedA family NP_828214.1 PF00132: Bacterial transferase hexapeptide (three repeats) NP_828215.1 PF00132: Bacterial transferase hexapeptide (three repeats) NP_828216.1 PF00892: Integral membrane protein DUF6 NP_828218.1 PF04073: YbaK / prolyl-tRNA synthetases associated domain NP_828219.1 PF01545: Cation efflux family NP_828223.1 PF04978: Protein of unknown function (DUF664) NP_828224.1 PF01545: Cation efflux family NP_828225.1 PF02629: CoA binding domain NP_828227.1 PF00300: Phosphoglycerate mutase family NP_828228.1 PF00324: Amino acid permease NP_828229.1 PF01205: Uncharacterized protein family UPF0029 NP_828230.1 PF00270: DEAD/DEAH box helicase NP_828231.1 PF00149: Calcineurin-like phosphoesterase NP_828232.1 PF02463: RecF/RecN/SMC N terminal domain NP_828234.1 PF00581: Rhodanese-like domain NP_828236.1 PF05960: Bacterial protein of unknown function (DUF885) NP_828239.1 PF00583: Acetyltransferase (GNAT) family NP_828242.1 PF00892: Integral membrane protein DUF6 NP_828243.1 PF00561: alpha/beta hydrolase fold NP_828253.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_828255.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_828256.1 PF01595: Domain of unknown function DUF21 NP_828257.1 PF01595: Domain of unknown function DUF21 NP_828258.1 PF00583: Acetyltransferase (GNAT) family NP_828264.1 PF01209: ubiE/COQ5 methyltransferase family NP_828267.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_828268.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_828269.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine NP_828270.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine NP_828271.1 PF04149: Domain of unknown function (DUF397) NP_828275.1 Seems to have no N-terminal signal sequence NP_828277.1 PF00574: Clp protease NP_828278.1 PF02604: Phd_YefM NP_828280.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter NP_828281.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active NP_828282.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_828283.1 PF01730: UreF NP_828284.1 PF02492: CobW/HypB/UreG, nucleotide-binding domain NP_828285.1 PF01774: UreD urease accessory protein NP_828286.1 PF00561: alpha/beta hydrolase fold NP_828289.1 PF02274: Amidinotransferase NP_828293.1 PF00474: Sodium:solute symporter family NP_828297.1 PF04554: Extensin-like region NP_828299.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_828300.1 PF07685: CobB/CobQ-like glutamine amidotransferase domain NP_828301.1 PF01225: Mur ligase family, catalytic domain NP_828304.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_828305.1 PF00190: Cupin NP_828306.1 CYP158A3, adjacent to rpp NP_828307.1 PhlD homolog, PF02797: Chalcone and stilbene synthases, C-terminal domain NP_828310.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate NP_828312.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA NP_828315.1 PF00107: Zinc-binding dehydrogenase NP_828316.1 PF02770: Acyl-CoA dehydrogenase, middle domain NP_828317.1 PF00441: Acyl-CoA dehydrogenase, C-terminal domain NP_828321.1 PF05610: Protein of unknown function (DUF779) NP_828322.1 PF07702: UbiC transcription regulator-associated NP_828323.1 inositol metabolism, PF00205: Thiamine pyrophosphate enzyme, central domain NP_828324.1 inositol metabolism, PF06845: Myo-inositol catabolism protein IolB NP_828325.1 PF07157: DNA circulation protein N-terminus NP_828326.1 inositol metabolism, PF00294: pfkB family carbohydrate kinase NP_828330.1 inositol metaqbolism, PF06960: Myo-inositol catabolism protein N-terminus NP_828331.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_828332.1 PF00532: Periplasmic binding proteins and sugar binding domain of the LacI family NP_828333.1 PF01740: STAS domain NP_828334.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_828337.1 nrps4 gene cluster NP_828338.1 nrps4 gene cluster NP_828339.1 nrps4 gene cluster NP_828340.1 nrps4 gene cluster NP_828341.1 nrps4 gene cluster NP_828344.1 PF01361: Tautomerase enzyme NP_828345.1 PF00107: Zinc-binding dehydrogenase NP_828348.1 PF01590: GAF domain NP_828353.1 PF00171: Aldehyde dehydrogenase family NP_828355.1 PF01510: N-acetylmuramoyl-L-alanine amidase NP_828357.2 PF00370: FGGY family of carbohydrate kinases, N-terminal domain NP_828358.1 catalyzes the interconversion of D-xylose to D-xylulose NP_828359.1 PF04886: PT repeat NP_828360.1 pks4 gene cluster NP_828361.1 pks4 gene cluster, PF03033: Glycosyltransferase family 28 N-terminal domain NP_828362.1 CYP105R1, pks4 gene cluster NP_828363.1 PF07690: Major Facilitator Superfamily NP_828364.1 PF01408: Oxidoreductase family, NAD-binding Rossmann fold NP_828365.1 PF00106: short chain dehydrogenase NP_828366.1 PF05721: Phytanoyl-CoA dioxygenase (PhyH) NP_828369.1 PF02541: Ppx/GppA phosphatase family NP_828374.1 PF00561: alpha/beta hydrolase fold NP_828375.1 PF01638: Transcriptional regulator NP_828376.1 PF00230: Major intrinsic protein NP_828377.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_828379.1 PF00266: Aminotransferase class-V NP_828383.1 PF03372: Endonuclease/Exonuclease/phosphatase family NP_828387.1 PF00583: Acetyltransferase (GNAT) family NP_828391.1 PF00924: Mechanosensitive ion channel NP_828392.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_828393.1 PF03706: Uncharacterised protein family (UPF0104) NP_828395.1 PF00912: Transglycosylase NP_828400.1 PF01576: Myosin tail NP_828402.1 PF00106: short chain dehydrogenase NP_828404.1 PF05976: Bacterial membrane protein of unknown function (DUF893) NP_828405.1 PF00107: Zinc-binding dehydrogenase NP_828407.1 PF01965: DJ-1/PfpI family NP_828409.1 PF00248: Aldo/keto reductase family NP_828410.1 PF07690: Major Facilitator Superfamily NP_828412.1 PF05651: Putative sugar diacid recognition NP_828413.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_828416.1 PF00376: MerR family regulatory protein NP_828417.1 PF07724: ATPase family associated with various cellular activities (AAA) NP_828420.1 PF00011: Hsp20/alpha crystallin family NP_828421.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_828425.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_828426.1 PF01551: Peptidase family M23 NP_828427.1 PF05653: Protein of unknown function (DUF803) NP_828428.1 PF06276: Ferric iron reductase protein FhuF NP_828429.1 PF00534: Glycosyl transferases group 1 NP_828430.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_828432.1 PF03007: Uncharacterised protein family (UPF0089) NP_828433.1 PF00106: short chain dehydrogenase NP_828435.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_828437.1 PF00583: Acetyltransferase (GNAT) family NP_828442.1 PF02065: Melibiase NP_828443.1 LacI-family transcriptional regulator NP_828457.1 PF02653: Branched-chain amino acid transport system / permease component NP_828459.1 PF00106: short chain dehydrogenase NP_828460.1 PF00248: Aldo/keto reductase family NP_828461.1 PF05336: Protein of unknown function (DUF718) NP_828462.1 PF04909: Amidohydrolase NP_828463.1 PF06762: Protein of unknown function (DUF1222) NP_828464.1 PF00785: PAC motif NP_828468.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and or membrane proteins NP_828470.1 PF00324: Amino acid permease NP_828471.1 PF00582: Universal stress protein family NP_828472.1 catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_828474.1 PF04203: Sortase family NP_828478.1 PF03640: repeat of unknown function NP_828479.1 PF04672: Protein of unknown function (DUF574) NP_828480.1 PF00563: EAL domain, PF00990: GGDEF domain, PF00785: PAC motif NP_828481.1 PF00106: short chain dehydrogenase NP_828484.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_828485.1 catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone NP_828490.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_828496.1 probably siderophore biosynthesis protein NP_828497.1 probably siderophore biosynthesis protein, PF04183: IucA / IucC family NP_828498.1 PF04183: IucA / IucC family NP_828499.1 probably siderophore biosynthesis protein NP_828500.1 PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NP_828501.1 PF03992: Antibiotic biosynthesis monooxygenase NP_828504.1 PF07311: Protein of unknown function (DUF1458) NP_828506.1 PF01590: GAF domain NP_828508.1 PF07690: Major Facilitator Superfamily NP_828511.1 PF03729: Short repeat of unknown function (DUF308) NP_828515.1 PF02553: Cobalt transport protein component CbiN NP_828516.1 PF03781: Domain of unknown function (DUF323) NP_828520.1 PF01145: SPFH domain / Band 7 family NP_828521.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia NP_828523.1 PF00085: Thioredoxin NP_828524.1 similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_828525.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_828526.1 PF03929: Uncharacterized iron-regulated membrane protein (DUF337) NP_828530.1 similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase NP_828531.1 PF02678: Pirin NP_828532.1 truncated NP_828534.1 PF04101: Glycosyltransferase family 28 C-terminal domain NP_828535.1 pks1 gene cluster, PF00561: alpha/beta hydrolase fold NP_828536.1 pks1 gene cluster NP_828537.1 pks1 gene cluster NP_828538.1 pks1 gene cluster NP_828541.1 similar to HoxX protein NP_828542.1 PF01058: NADH ubiquinone oxidoreductase, 20 Kd subunit NP_828543.1 PF00374: Nickel-dependent hydrogenase NP_828544.1 similar to Ralstonia eutropha gi:38637731 NP_828545.1 similar to Ralstonia eutropha gi:38637732 NP_828546.1 similar to Ralstonia eutropha gi:38637733 NP_828547.1 similar to Ralstonia eutropha gi:38637734 NP_828548.1 similar to Ralstonia eutropha gi:38637735, PF01750: Hydrogenase maturation protease NP_828549.1 PF01155: Hydrogenase expression/synthesis hypA family NP_828550.1 PF02492: CobW/HypB/UreG, nucleotide-binding domain NP_828551.1 PF01300: yrdC domain NP_828552.1 PF01455: HupF/HypC family NP_828553.1 PF01924: Hydrogenase formation hypA family NP_828554.1 PF02769: AIR synthase related protein, C-terminal domain NP_828558.1 PF01799: [2Fe-2S] binding domain NP_828559.1 PF00941: FAD binding domain in molybdopterin dehydrogenase NP_828560.1 PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain NP_828563.1 PF02342: Bacterial stress protein NP_828565.1 PF00999: Sodium/hydrogen exchanger family NP_828566.1 PF02080: TrkA-C domain NP_828572.1 alpha-amylase family NP_828574.1 frameshift NP_828575.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_828576.1 RNA polymerase alternative sigma factor NP_828577.1 PF03861: ANTAR domain NP_828578.1 PF03364: Streptomyces cyclase/dehydrase NP_828579.1 PF00296: Luciferase-like monooxygenase NP_828580.1 PF02687: Predicted permease NP_828586.1 PF02589: Uncharacterized ACR, YkgG family COG1556 NP_828596.1 PF05336: Protein of unknown function (DUF718) NP_828599.1 PF00561: alpha/beta hydrolase fold NP_828601.1 PF00805: Pentapeptide repeats (8 copies) NP_828602.1 CYP102B2 NP_828607.1 PF06081: Bacterial protein of unknown function (DUF939) NP_828609.1 PF05139: Erythromycin esterase NP_828614.1 PF00106: short chain dehydrogenase NP_828615.1 PF00702: haloacid dehalogenase-like hydrolase NP_828616.1 PF02231: PHP domain N-terminal region NP_828619.1 PF04892: VanZ like family NP_828620.1 PF04066: Multiple resistance and pH regulation protein F (MrpF / PhaF) NP_828622.1 PF04039: Domain related to MnhB subunit of Na+/H+ antiporter NP_828623.1 PF00420: NADH-ubiquinone/plastoquinone oxidore NP_828624.1 PF00361: NADH-Ubiquinone/plastoquinone (complex I), various chains NP_828626.1 PF00009: Elongation factor Tu GTP binding domain NP_828628.1 PF01740: STAS domain NP_828629.1 PF00107: Zinc-binding dehydrogenase NP_828634.1 PF06993: Protein of unknown function (DUF1304) NP_828636.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_828637.1 PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NP_828639.1 PF00043: Glutathione S-transferase, C-terminal domain NP_828640.1 PF01545: Cation efflux family NP_828641.1 PF04075: Domain of unknown function (DUF385) NP_828642.1 PF01810: LysE type translocator NP_828643.1 PF00657: GDSL-like Lipase/Acylhydrolase NP_828645.1 CYP105D7, fdxH is located at downstream NP_828648.1 PF07080: Protein of unknown function (DUF1348) NP_828649.1 possible flavoprotein involved in panthothenate metabolism NP_828651.1 PF00561: alpha/beta hydrolase fold NP_828652.1 PF00652: QXW lectin repeat NP_828653.1 PF02040: Arsenical pump membrane protein NP_828654.1 PF01590: GAF domain NP_828656.1 PF00652: QXW lectin repeat NP_828657.1 PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NP_828658.1 PF01070: FMN-dependent dehydrogenase NP_828659.1 PF01243: Pyridoxamine 5'-phosphate oxidase NP_828662.1 subtilase-type; inhibits bacterial serine proteases NP_828664.1 PF00583: Acetyltransferase (GNAT) family NP_828665.1 PF01569: PAP2 superfamily NP_828666.1 PF07690: Major Facilitator Superfamily NP_828667.1 PF05146: Aha1 domain NP_828670.1 PF00364: Biotin-requiring enzyme NP_828672.1 PF03061: Thioesterase superfamily NP_828673.1 PF02983: Alpha-lytic protease prodomain NP_828674.1 PF01590: GAF domain NP_828675.1 AmfR homolog protein NP_828676.1 AmfA/RamB homolog protein NP_828677.1 AmfB/RamA homolog protein NP_828678.1 AmfS/RamS homolog protein NP_828679.1 AmfT homolog protein NP_828680.1 PF01590: GAF domain NP_828681.1 PF00149: Calcineurin-like phosphoesterase NP_828683.1 PF00009: Elongation factor Tu GTP binding domain NP_828684.1 PF00150: Cellulase (glycosyl hydrolase family 5) NP_828687.1 IS630 family NP_828688.1 IS110 family NP_828689.1 IS630 family, inserted IS900-like sequence. Inverted repeat sequence (11 bp). Target sequence (CTAG). NP_828691.1 PF00990: GGDEF domain NP_828696.1 ATP/GTP-binding NP_828700.1 PF00823: PPE family NP_828701.1 PF06519: TolA protein NP_828706.1 PF03992: Antibiotic biosynthesis monooxygenase NP_828710.1 PF02153: Prephenate dehydrogenase NP_828711.1 PF00702: haloacid dehalogenase-like hydrolase NP_828722.1 IS21 family, truncated NP_828723.1 IS21 family, truncated NP_828737.1 PF05729: NACHT domain NP_828739.1 PF00652: QXW lectin repeat NP_828750.1 SAP1_1 NP_828751.1 SAP1_2 NP_828752.1 SAP1_3 NP_828753.1 SAP1_4 NP_828754.1 SAP1_5 NP_828755.1 SAP1_6 NP_828756.1 SAP1_7 NP_828757.1 SAP1_8 NP_828758.1 SAP1_9 NP_828759.1 SAP1_10 NP_828760.1 SAP1_11 NP_828761.1 SAP1_12 NP_828762.1 SAP1_13 NP_828763.1 SAP1_14 NP_828764.1 SAP1_15 NP_828765.1 SAP1_16 NP_828766.1 SAP1_17 NP_828767.1 SAP1_18 NP_828768.1 SAP1_19 NP_828769.1 SAP1_20 NP_828770.1 SAP1_21 NP_828771.1 SAP1_22 NP_828772.1 SAP1_23 NP_828773.1 SAP1_24 NP_828774.1 SAP1_25 NP_828775.1 SAP1_26 NP_828776.1 SAP1_27 NP_828777.1 SAP1_28 NP_828778.1 SAP1_29 NP_828779.1 SAP1_30 NP_828780.1 SAP1_31 NP_828781.1 SAP1_32 NP_828782.1 SAP1_33 NP_828783.1 SAP1_34 NP_828784.1 SAP1_35 NP_828785.1 SAP1_36 NP_828786.1 SAP1_37 NP_828787.1 SAP1_38 NP_828788.1 SAP1_39 NP_828789.1 SAP1_40 NP_828790.1 SAP1_41 NP_828791.1 SAP1_42 NP_828792.1 SAP1_43 NP_828793.1 SAP1_44 NP_828794.1 SAP1_45 NP_828795.1 SAP1_46 NP_828796.1 SAP1_47 NP_828797.1 SAP1_48 NP_828798.1 SAP1_49 NP_828799.1 SAP1_50 NP_828800.1 SAP1_51 NP_828801.1 SAP1_52 NP_828802.1 SAP1_53 NP_828803.1 SAP1_54 NP_828804.1 SAP1_55 NP_828805.1 SAP1_56 NP_828806.1 SAP1_57 NP_828807.1 SAP1_58 NP_828808.1 SAP1_59 NP_828809.1 SAP1_60 NP_828810.1 SAP1_61 NP_828811.1 SAP1_62 NP_828812.1 SAP1_63 NP_828813.1 SAP1_64 NP_828814.1 SAP1_65 NP_828815.1 SAP1_66 NP_828816.1 SAP1_67 NP_828817.1 SAP1_68 NP_828818.1 SAP1_69 NP_828819.1 ParB nuclease; SAP1_70 NP_828820.1 ParA ATPase; SAP1_71 NP_828821.1 SAP1_72 NP_828822.1 SAP1_73 NP_828823.1 SAP1_74 NP_828824.1 SAP1_75 NP_828825.1 SAP1_76 NP_828826.1 SAP1_77 NP_828827.1 SAP1_78 NP_828828.1 SAP1_79 NP_828829.1 SAP1_80 NP_828830.1 SAP1_81 NP_828831.1 SAP1_82 NP_828832.1 SAP1_83 NP_828833.1 SAP1_84 NP_828834.1 SAP1_85 NP_828835.1 SAP1_86 NP_828836.1 SAP1_87 NP_828837.1 SAP1_88 NP_828838.1 SAP1_89 NP_828839.1 SAP1_90 NP_828840.1 SAP1_91 NP_828841.1 SAP1_92 NP_828842.1 SAP1_93 NP_828843.1 SAP1_94 NP_828844.1 SAP1_95 NP_828845.1 SAP1_96