-- dump date 20111121_015053 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 227882000001 SEQ_END SEQ_END NC_003155.4 9025608 9025608 DR NC_003155.4; contig end 9025608..9025608 Streptomyces avermitilis MA-4680 227882000002 SEQ_END SEQ_END NC_004719.1 94287 94287 DR NC_004719.1; contig end 94287..94287 Streptomyces avermitilis MA-4680 NP_821175.1 CDS SAV_1 NC_003155.4 1380 1811 R hypothetical protein complement(1380..1811) Streptomyces avermitilis MA-4680 1211754 NP_821176.1 CDS SAV_2 NC_003155.4 2466 2699 D PF04851: Type III restriction enzyme, res subunit; hypothetical protein 2466..2699 Streptomyces avermitilis MA-4680 1211755 NP_821177.1 CDS SAV_3 NC_003155.4 2765 3310 D endonuclease VII 2765..3310 Streptomyces avermitilis MA-4680 1211756 NP_821178.1 CDS SAV_4 NC_003155.4 3433 3939 R hypothetical protein complement(3433..3939) Streptomyces avermitilis MA-4680 1211757 NP_821179.1 CDS SAV_5 NC_003155.4 3994 4932 D PF07336: Protein of unknown function (DUF1470); hypothetical protein 3994..4932 Streptomyces avermitilis MA-4680 1211758 NP_821180.1 CDS SAV_6 NC_003155.4 4936 7563 D helicase 4936..7563 Streptomyces avermitilis MA-4680 1211759 NP_821181.1 CDS SAV_7 NC_003155.4 7554 9626 D PF00589: Phage integrase family; transposase 7554..9626 Streptomyces avermitilis MA-4680 1211760 NP_821182.1 CDS SAV_8 NC_003155.4 9886 10635 R hypothetical protein complement(9886..10635) Streptomyces avermitilis MA-4680 1211761 NP_821183.1 CDS SAV_9 NC_003155.4 10632 10805 R hypothetical protein complement(10632..10805) Streptomyces avermitilis MA-4680 1211762 NP_821184.1 CDS SAV_10 NC_003155.4 11101 13497 R hypothetical protein complement(11101..13497) Streptomyces avermitilis MA-4680 1211763 NP_821185.1 CDS SAV_11 NC_003155.4 13376 15523 R PF00004: ATPase family associated with various cellular activities (AAA); hypothetical protein complement(13376..15523) Streptomyces avermitilis MA-4680 1211764 NP_821186.1 CDS SAV_12 NC_003155.4 15815 17701 R PF00805: Pentapeptide repeats (8 copies); hypothetical protein complement(15815..17701) Streptomyces avermitilis MA-4680 1211765 NP_821187.1 CDS SAV_13 NC_003155.4 17828 18922 D PF03457: Helicase associated domain; hypothetical protein 17828..18922 Streptomyces avermitilis MA-4680 1211766 NP_821188.1 CDS SAV_14 NC_003155.4 19446 20279 D hypothetical protein 19446..20279 Streptomyces avermitilis MA-4680 1211767 NP_821189.1 CDS SAV_15 NC_003155.4 21562 22080 D hypothetical protein 21562..22080 Streptomyces avermitilis MA-4680 1211768 NP_821190.1 CDS SAV_16 NC_003155.4 22243 22770 D hypothetical protein 22243..22770 Streptomyces avermitilis MA-4680 1211769 NP_821191.1 CDS SAV_17 NC_003155.4 23457 23621 D hypothetical protein 23457..23621 Streptomyces avermitilis MA-4680 1211770 NP_821192.1 CDS SAV_18 NC_003155.4 23675 24559 D IS1647-like transposase 23675..24559 Streptomyces avermitilis MA-4680 1211771 NP_821193.1 CDS SAV_19 NC_003155.4 24570 24983 R hypothetical protein complement(24570..24983) Streptomyces avermitilis MA-4680 1211772 NP_821194.1 CDS SAV_20 NC_003155.4 25166 25690 R hypothetical protein complement(25166..25690) Streptomyces avermitilis MA-4680 1211773 NP_821195.1 CDS rhsA NC_003155.4 25699 29451 R PF05593: RHS Repeat; Rhs protein complement(25699..29451) Streptomyces avermitilis MA-4680 1211774 NP_821196.1 CDS SAV_22 NC_003155.4 29508 30080 R hypothetical protein complement(29508..30080) Streptomyces avermitilis MA-4680 1211775 NP_821197.1 CDS SAV_23 NC_003155.4 30107 30394 R hypothetical protein complement(30107..30394) Streptomyces avermitilis MA-4680 1211776 NP_821198.1 CDS SAV_24 NC_003155.4 30394 31323 R hypothetical protein complement(30394..31323) Streptomyces avermitilis MA-4680 1211777 NP_821199.1 CDS SAV_25 NC_003155.4 32197 32559 R hypothetical protein complement(32197..32559) Streptomyces avermitilis MA-4680 1211778 NP_821200.1 CDS sig1 NC_003155.4 32552 33124 R ECF subfamily RNA polymerase sigma factor complement(32552..33124) Streptomyces avermitilis MA-4680 1210016 NP_821201.1 CDS SAV_27 NC_003155.4 33121 33411 R hypothetical protein complement(33121..33411) Streptomyces avermitilis MA-4680 1211779 NP_821202.1 CDS SAV_28 NC_003155.4 34056 35792 D two-component system sensor kinase 34056..35792 Streptomyces avermitilis MA-4680 1211780 NP_821203.1 CDS SAV_29 NC_003155.4 37315 37656 D ParR family transcriptional regulator 37315..37656 Streptomyces avermitilis MA-4680 1211781 NP_821204.1 CDS SAV_30 NC_003155.4 37653 38609 D hypothetical protein 37653..38609 Streptomyces avermitilis MA-4680 1211782 NP_821205.1 CDS SAV_31 NC_003155.4 38623 39624 D PF01569: PAP2 superfamily; prepilin peptidase-like protein 38623..39624 Streptomyces avermitilis MA-4680 1211783 NP_821206.1 CDS SAV_32 NC_003155.4 41010 41612 D hypothetical protein 41010..41612 Streptomyces avermitilis MA-4680 1211784 NP_821207.1 CDS SAV_33 NC_003155.4 41665 41967 R hypothetical protein complement(41665..41967) Streptomyces avermitilis MA-4680 1211785 NP_821208.1 CDS SAV_34 NC_003155.4 42010 44046 D hypothetical protein 42010..44046 Streptomyces avermitilis MA-4680 1211786 NP_821209.1 CDS SAV_35 NC_003155.4 44107 44958 R hypothetical protein complement(44107..44958) Streptomyces avermitilis MA-4680 1211787 NP_821210.1 CDS SAV_36 NC_003155.4 45160 45432 R hypothetical protein complement(45160..45432) Streptomyces avermitilis MA-4680 1211788 NP_821211.1 CDS SAV_37 NC_003155.4 45819 47141 R hypothetical protein complement(45819..47141) Streptomyces avermitilis MA-4680 1211789 NP_821212.1 CDS SAV_38 NC_003155.4 47239 48180 R PF00561: alpha/beta hydrolase fold; hydrolase complement(47239..48180) Streptomyces avermitilis MA-4680 1211790 NP_821213.1 CDS SAV_39 NC_003155.4 49166 49456 D probably pseudogene; terminal protein Tpg-like protein 49166..49456 Streptomyces avermitilis MA-4680 1211791 NP_821214.1 CDS SAV_40 NC_003155.4 49694 50434 R hypothetical protein complement(49694..50434) Streptomyces avermitilis MA-4680 1211792 NP_821215.1 CDS SAV_41 NC_003155.4 50521 50901 R hypothetical protein complement(50521..50901) Streptomyces avermitilis MA-4680 1211793 NP_821216.1 CDS SAV_42 NC_003155.4 51232 52623 D hypothetical protein 51232..52623 Streptomyces avermitilis MA-4680 1211794 NP_821217.1 CDS SAV_43 NC_003155.4 53113 53505 D Tn5741 family, partial; Tn5741 family transposase 53113..53505 Streptomyces avermitilis MA-4680 1211795 NP_821218.1 CDS SAV_44 NC_003155.4 54215 55330 D PF07470: Glycosyl Hydrolase Family 88; unsaturated glucuronyl hydrolase 54215..55330 Streptomyces avermitilis MA-4680 1211796 NP_821219.1 CDS SAV_45 NC_003155.4 55687 56061 R IS5 family transposase complement(55687..56061) Streptomyces avermitilis MA-4680 1211797 NP_821220.1 CDS SAV_46 NC_003155.4 56052 56441 R IS5 family; IS1647-like transposase complement(56052..56441) Streptomyces avermitilis MA-4680 1211798 NP_821221.1 CDS SAV_47 NC_003155.4 56620 57810 D IS200/IS605 family; IS200-like transposase 56620..57810 Streptomyces avermitilis MA-4680 1211799 NP_821222.1 CDS SAV_48 NC_003155.4 58168 58824 R hypothetical protein complement(58168..58824) Streptomyces avermitilis MA-4680 1211800 NP_821223.1 CDS SAV_49 NC_003155.4 58919 59212 D hypothetical protein 58919..59212 Streptomyces avermitilis MA-4680 1211801 NP_821224.1 CDS SAV_50 NC_003155.4 59260 61488 R hypothetical protein complement(59260..61488) Streptomyces avermitilis MA-4680 1211802 NP_821225.1 CDS SAV_51 NC_003155.4 62242 62751 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(62242..62751) Streptomyces avermitilis MA-4680 1211803 NP_821226.1 CDS SAV_52 NC_003155.4 62965 63342 R hypothetical protein complement(62965..63342) Streptomyces avermitilis MA-4680 1211804 NP_821227.1 CDS SAV_53 NC_003155.4 63529 64401 D transcriptional regulatory protein 63529..64401 Streptomyces avermitilis MA-4680 1211805 NP_821228.1 CDS SAV_54 NC_003155.4 64481 64588 R hypothetical protein complement(64481..64588) Streptomyces avermitilis MA-4680 1211806 NP_821229.1 CDS SAV_55 NC_003155.4 64632 65045 R hypothetical protein complement(64632..65045) Streptomyces avermitilis MA-4680 1211807 NP_821230.1 CDS SAV_56 NC_003155.4 65216 65398 R hypothetical protein complement(65216..65398) Streptomyces avermitilis MA-4680 1211808 NP_821231.1 CDS SAV_57 NC_003155.4 65536 66591 R PF01833: IPT/TIG domain; hypothetical protein complement(65536..66591) Streptomyces avermitilis MA-4680 1211809 NP_821232.1 CDS SAV_58 NC_003155.4 66803 67546 R PF01833: IPT/TIG domain; hypothetical protein complement(66803..67546) Streptomyces avermitilis MA-4680 1211810 NP_821233.1 CDS SAV_59 NC_003155.4 69136 69402 D hypothetical protein 69136..69402 Streptomyces avermitilis MA-4680 1211811 NP_821234.1 CDS SAV_60 NC_003155.4 70102 70617 R hypothetical protein complement(70102..70617) Streptomyces avermitilis MA-4680 1211812 NP_821235.1 CDS SAV_61 NC_003155.4 70718 71920 R IS200/IS605 family; IS200-like transposase complement(70718..71920) Streptomyces avermitilis MA-4680 1211813 NP_821236.1 CDS SAV_62 NC_003155.4 72189 72680 D transmembrane transport protein 72189..72680 Streptomyces avermitilis MA-4680 1211814 NP_821237.1 CDS SAV_63 NC_003155.4 72680 72901 D transcriptional regulatory protein 72680..72901 Streptomyces avermitilis MA-4680 1211815 NP_821238.1 CDS SAV_64 NC_003155.4 73063 73698 D hypothetical protein 73063..73698 Streptomyces avermitilis MA-4680 1211816 NP_821239.1 CDS SAV_65 NC_003155.4 74098 74520 D hypothetical protein 74098..74520 Streptomyces avermitilis MA-4680 1211817 NP_821240.1 CDS SAV_66 NC_003155.4 74429 74899 R IS200/IS605 family, truncated; IS200-like transposase complement(74429..74899) Streptomyces avermitilis MA-4680 1211818 NP_821241.1 CDS SAV_67 NC_003155.4 75600 76676 D PF00165: Bacterial regulatory helix-turn-helix proteins, araC family; regulatory protein 75600..76676 Streptomyces avermitilis MA-4680 1211819 NP_821242.1 CDS SAV_68 NC_003155.4 77069 78430 D hypothetical protein 77069..78430 Streptomyces avermitilis MA-4680 1211820 NP_821243.1 CDS SAV_69 NC_003155.4 78733 78972 D hypothetical protein 78733..78972 Streptomyces avermitilis MA-4680 1211821 NP_821244.1 CDS SAV_70 NC_003155.4 79005 79262 R hypothetical protein complement(79005..79262) Streptomyces avermitilis MA-4680 1211822 NP_821245.1 CDS SAV_71 NC_003155.4 79425 79850 D PF03364: Streptomyces cyclase/dehydrase; putavie cyclase/dehydrase 79425..79850 Streptomyces avermitilis MA-4680 1211823 NP_821246.1 CDS SAV_72 NC_003155.4 80560 82215 R two-component system sensor kinase complement(80560..82215) Streptomyces avermitilis MA-4680 1211824 NP_821247.1 CDS SAV_73 NC_003155.4 82208 82954 R two-component system response regulator complement(82208..82954) Streptomyces avermitilis MA-4680 1211825 NP_821248.1 CDS SAV_74 NC_003155.4 83059 84600 D hypothetical protein 83059..84600 Streptomyces avermitilis MA-4680 1211826 NP_821249.1 CDS SAV_75 NC_003155.4 85042 85431 D PF01042: Endoribonuclease L-PSP; endoribonuclease L-PSP 85042..85431 Streptomyces avermitilis MA-4680 1211827 NP_821250.1 CDS tpc1 NC_003155.4 86073 87080 D terpene biosynthesis; terpene cyclase 86073..87080 Streptomyces avermitilis MA-4680 1210017 NP_821251.1 CDS SAV_77 NC_003155.4 87168 87629 R truncated methyltransferase; hypothetical protein complement(87168..87629) Streptomyces avermitilis MA-4680 1211828 NP_821252.1 CDS SAV_78 NC_003155.4 87716 88276 R hypothetical protein complement(87716..88276) Streptomyces avermitilis MA-4680 1211829 NP_821253.2 CDS SAV_79 NC_003155.4 88693 89706 R hypothetical protein complement(88693..89706) Streptomyces avermitilis MA-4680 1211830 NP_821254.1 CDS SAV_80 NC_003155.4 89844 90179 R mycinamicin resistance protein homolog; rRNA methyltransferase complement(89844..90179) Streptomyces avermitilis MA-4680 1211831 NP_821255.1 CDS SAV_81 NC_003155.4 90422 91192 R PF01522: Polysaccharide deacetylase; oligosaccharide deacetylase complement(90422..91192) Streptomyces avermitilis MA-4680 1211832 NP_821256.1 CDS SAV_82 NC_003155.4 91736 92317 R TetR family transcriptional regulator complement(91736..92317) Streptomyces avermitilis MA-4680 1211833 NP_821257.1 CDS SAV_83 NC_003155.4 92523 92741 D hypothetical protein 92523..92741 Streptomyces avermitilis MA-4680 1211834 NP_821258.1 CDS SAV_84 NC_003155.4 92939 94183 R PF05139: Erythromycin esterase; hypothetical protein complement(92939..94183) Streptomyces avermitilis MA-4680 1211835 NP_821259.1 CDS SAV_85 NC_003155.4 94242 95009 D MerR family transcriptional regulator 94242..95009 Streptomyces avermitilis MA-4680 1211836 NP_821260.1 CDS SAV_86 NC_003155.4 95110 96105 R LuxR-family transcriptional regulatory protein; erythropoiesis-stimulating protein complement(95110..96105) Streptomyces avermitilis MA-4680 1211837 NP_821261.1 CDS SAV_87 NC_003155.4 96235 96567 D hypothetical protein 96235..96567 Streptomyces avermitilis MA-4680 1211838 NP_821262.1 CDS SAV_88 NC_003155.4 99274 100050 R PF00125: Core histone H2A/H2B/H3/H4; hypothetical protein complement(99274..100050) Streptomyces avermitilis MA-4680 1211839 NP_821263.1 CDS SAV_89 NC_003155.4 100279 100866 R PF03752: Short repeats of unknown function; hypothetical protein complement(100279..100866) Streptomyces avermitilis MA-4680 1211840 NP_821264.1 CDS SAV_90 NC_003155.4 100955 101362 D hydrolase 100955..101362 Streptomyces avermitilis MA-4680 1211841 NP_821265.1 CDS SAV_91 NC_003155.4 101447 101893 D hypothetical protein 101447..101893 Streptomyces avermitilis MA-4680 1211842 NP_821266.1 CDS SAV_92 NC_003155.4 102549 103163 D PF04203: Sortase family; lipoprotein 102549..103163 Streptomyces avermitilis MA-4680 1211843 NP_821267.1 CDS sig2 NC_003155.4 103255 103746 D ECF subfamily RNA polymerase sigma factor 103255..103746 Streptomyces avermitilis MA-4680 1210018 NP_821268.1 CDS SAV_94 NC_003155.4 103709 104197 D hypothetical protein 103709..104197 Streptomyces avermitilis MA-4680 1211844 NP_821269.1 CDS SAV_95 NC_003155.4 104696 106234 D protein 104696..106234 Streptomyces avermitilis MA-4680 1211845 NP_821270.1 CDS SAV_96 NC_003155.4 106628 107440 D hypothetical protein 106628..107440 Streptomyces avermitilis MA-4680 1211846 NP_821271.1 CDS SAV_97 NC_003155.4 107491 108027 R hypothetical protein complement(107491..108027) Streptomyces avermitilis MA-4680 1211847 NP_821272.1 CDS SAV_98 NC_003155.4 108349 110238 R PF00723: Glycosyl hydrolases family 15; glycosyl hydrolase complement(108349..110238) Streptomyces avermitilis MA-4680 1211848 NP_821273.1 CDS SAV_99 NC_003155.4 110830 113364 D PF03176: MMPL family; integral membrane protein 110830..113364 Streptomyces avermitilis MA-4680 1211849 NP_821274.1 CDS pks11-1 NC_003155.4 113361 114866 D pks11; polyketide synthase 113361..114866 Streptomyces avermitilis MA-4680 1211850 NP_821275.1 CDS pks11-2 NC_003155.4 114860 118594 D pks11 containing aminotransferase domain; polyketide synthase 114860..118594 Streptomyces avermitilis MA-4680 1211851 NP_821276.1 CDS SAV_102 NC_003155.4 118868 119221 R hypothetical protein complement(118868..119221) Streptomyces avermitilis MA-4680 1211852 NP_821277.1 CDS SAV_103 NC_003155.4 119461 120039 D IS256 family transposase 119461..120039 Streptomyces avermitilis MA-4680 1211853 NP_821278.1 CDS SAV_104 NC_003155.4 120102 120611 D IS256 family, partial; IS256 family transposase 120102..120611 Streptomyces avermitilis MA-4680 1211854 NP_821279.1 CDS SAV_105 NC_003155.4 121935 122162 R hypothetical protein complement(121935..122162) Streptomyces avermitilis MA-4680 1211855 NP_821280.1 CDS SAV_106 NC_003155.4 123637 124200 D hypothetical protein 123637..124200 Streptomyces avermitilis MA-4680 1211856 NP_821281.1 CDS SAV_107 NC_003155.4 124557 124883 D hypothetical protein 124557..124883 Streptomyces avermitilis MA-4680 1211857 NP_821282.1 CDS SAV_108 NC_003155.4 124945 125364 D hypothetical protein 124945..125364 Streptomyces avermitilis MA-4680 1211858 NP_821283.1 CDS cyp1 NC_003155.4 125995 127230 D CYP154A2; cytochrome P450 hydroxylase 125995..127230 Streptomyces avermitilis MA-4680 1210019 NP_821284.1 CDS SAV_110 NC_003155.4 127243 128214 D IS112 homolog; transposase 127243..128214 Streptomyces avermitilis MA-4680 1211859 NP_821285.1 CDS SAV_111 NC_003155.4 128414 128743 R LuxR family transcriptional regulator complement(128414..128743) Streptomyces avermitilis MA-4680 1211860 NP_821286.1 CDS SAV_112 NC_003155.4 129497 132031 D PF01590: GAF domain; hypothetical protein 129497..132031 Streptomyces avermitilis MA-4680 1211861 NP_821287.1 CDS SAV_113 NC_003155.4 132082 132333 D hypothetical protein 132082..132333 Streptomyces avermitilis MA-4680 1211862 NP_821288.1 CDS SAV_114 NC_003155.4 132479 133000 D IS6 family transposase 132479..133000 Streptomyces avermitilis MA-4680 1211863 NP_821289.1 CDS SAV_115 NC_003155.4 132949 133668 D IS6 family; IS6 family transposase 132949..133668 Streptomyces avermitilis MA-4680 1211864 NP_821290.1 CDS SAV_116 NC_003155.4 133696 134031 D hypothetical protein 133696..134031 Streptomyces avermitilis MA-4680 1211865 NP_821291.1 CDS SAV_117 NC_003155.4 134166 134822 D hypothetical protein 134166..134822 Streptomyces avermitilis MA-4680 1211866 NP_821292.1 CDS SAV_118 NC_003155.4 136682 137041 D IS1647-like transposase 136682..137041 Streptomyces avermitilis MA-4680 1211867 NP_821293.2 CDS SAV_119 NC_003155.4 136846 137490 D IS1647-like transposase 136846..137490 Streptomyces avermitilis MA-4680 1211868 NP_821294.1 CDS SAV_120 NC_003155.4 137556 138740 D IS4 family transposase 137556..138740 Streptomyces avermitilis MA-4680 1211869 NP_821295.1 CDS SAV_121 NC_003155.4 138932 139393 D hypothetical protein 138932..139393 Streptomyces avermitilis MA-4680 1211870 NP_821296.1 CDS SAV_122 NC_003155.4 139360 140565 R IS110 family transposase complement(139360..140565) Streptomyces avermitilis MA-4680 1211871 NP_821297.1 CDS SAV_123 NC_003155.4 140787 141911 D PF01135: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); O-methyltransferase 140787..141911 Streptomyces avermitilis MA-4680 1211872 NP_821298.1 CDS SAV_124 NC_003155.4 141787 142821 R hypothetical protein complement(141787..142821) Streptomyces avermitilis MA-4680 1211873 NP_821299.1 CDS SAV_125 NC_003155.4 142975 143661 D PF00597: DedA family; hypothetical protein 142975..143661 Streptomyces avermitilis MA-4680 1211874 NP_821300.1 CDS SAV_126 NC_003155.4 143658 144263 D PF01569: PAP2 superfamily; integral membrane protein 143658..144263 Streptomyces avermitilis MA-4680 1211875 NP_821301.1 CDS SAV_127 NC_003155.4 144260 144988 D PF01569: PAP2 superfamily; hypothetical protein 144260..144988 Streptomyces avermitilis MA-4680 1211876 NP_821302.1 CDS SAV_128 NC_003155.4 144942 145604 D two-component system response regulator 144942..145604 Streptomyces avermitilis MA-4680 1211877 NP_821303.1 CDS SAV_129 NC_003155.4 145601 146962 D two-component system sensor kinase 145601..146962 Streptomyces avermitilis MA-4680 1211878 NP_821304.1 CDS SAV_130 NC_003155.4 146943 147743 R PF03988: Repeat of Unknown Function (DUF347); integral membrane protein complement(146943..147743) Streptomyces avermitilis MA-4680 1211879 NP_821305.1 CDS SAV_131 NC_003155.4 147993 148823 R PF03988: Repeat of Unknown Function (DUF347); integral membrane protein complement(147993..148823) Streptomyces avermitilis MA-4680 1211880 NP_821306.1 CDS SAV_132 NC_003155.4 148993 149274 D hypothetical protein 148993..149274 Streptomyces avermitilis MA-4680 1211881 NP_821307.1 CDS SAV_133 NC_003155.4 149373 150071 D transporter 149373..150071 Streptomyces avermitilis MA-4680 1211882 NP_821308.1 CDS SAV_134 NC_003155.4 150032 151414 R two-component system sensor kinase complement(150032..151414) Streptomyces avermitilis MA-4680 1211883 NP_821309.1 CDS SAV_135 NC_003155.4 151606 152274 D lipoprotein 151606..152274 Streptomyces avermitilis MA-4680 1211884 NP_821310.1 CDS SAV_136 NC_003155.4 152278 153018 D ABC transporter ATP-binding protein 152278..153018 Streptomyces avermitilis MA-4680 1211885 NP_821311.1 CDS SAV_137 NC_003155.4 153005 153718 D ABC transporter ATP-binding protein 153005..153718 Streptomyces avermitilis MA-4680 1211886 NP_821312.1 CDS SAV_138 NC_003155.4 153715 156363 D PF02687: Predicted permease; ABC transporter permease 153715..156363 Streptomyces avermitilis MA-4680 1211887 NP_821313.1 CDS SAV_139 NC_003155.4 156360 157139 D two-component system response regulator 156360..157139 Streptomyces avermitilis MA-4680 1211888 NP_821314.1 CDS SAV_140 NC_003155.4 157954 158928 R hydroxylase complement(157954..158928) Streptomyces avermitilis MA-4680 1211889 NP_821315.1 CDS ephA1 NC_003155.4 158997 160031 R PF00561: alpha/beta hydrolase fold; epoxide hydrolase complement(158997..160031) Streptomyces avermitilis MA-4680 1211890 NP_821316.1 CDS SAV_142 NC_003155.4 160053 160754 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(160053..160754) Streptomyces avermitilis MA-4680 1211891 NP_821317.1 CDS SAV_143 NC_003155.4 161392 161961 R TetR family transcriptional regulator complement(161392..161961) Streptomyces avermitilis MA-4680 1211892 NP_821318.1 CDS SAV_144 NC_003155.4 162195 163493 R PF01061: ABC-2 type transporter; hypothetical protein complement(162195..163493) Streptomyces avermitilis MA-4680 1211893 NP_821319.1 CDS SAV_145 NC_003155.4 163767 165950 R PF03176: MMPL family; membrane tranport protein complement(163767..165950) Streptomyces avermitilis MA-4680 1211894 NP_821320.1 CDS SAV_146 NC_003155.4 166102 166851 D TetR family transcriptional regulator 166102..166851 Streptomyces avermitilis MA-4680 1211895 NP_821321.1 CDS SAV_147 NC_003155.4 167014 167367 D hypothetical protein 167014..167367 Streptomyces avermitilis MA-4680 1211896 NP_821322.1 CDS SAV_148 NC_003155.4 167757 168923 R PF03022: Major royal jelly protein; hypothetical protein complement(167757..168923) Streptomyces avermitilis MA-4680 1211897 NP_821323.1 CDS SAV_149 NC_003155.4 169217 169735 R hypothetical protein complement(169217..169735) Streptomyces avermitilis MA-4680 1211898 NP_821324.1 CDS SAV_150 NC_003155.4 169801 170613 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(169801..170613) Streptomyces avermitilis MA-4680 1211899 NP_821325.1 CDS SAV_151 NC_003155.4 171402 172043 R TetR family transcriptional regulator complement(171402..172043) Streptomyces avermitilis MA-4680 1211900 NP_821326.1 CDS SAV_152 NC_003155.4 172191 173102 D PF00106: short chain dehydrogenase; short chain dehydrogenase 172191..173102 Streptomyces avermitilis MA-4680 1211901 NP_821327.1 CDS SAV_153 NC_003155.4 173107 174243 D hypothetical protein 173107..174243 Streptomyces avermitilis MA-4680 1211902 NP_821328.1 CDS SAV_154 NC_003155.4 174240 175163 D PF00561: alpha/beta hydrolase fold; hydrolase 174240..175163 Streptomyces avermitilis MA-4680 1211903 NP_821329.1 CDS SAV_155 NC_003155.4 175255 176166 D hypothetical protein 175255..176166 Streptomyces avermitilis MA-4680 1211904 NP_821330.1 CDS SAV_156 NC_003155.4 176190 177290 D PF00111: 2Fe-2S iron-sulfur cluster binding domain; iron-sulfur oxidoreductase 176190..177290 Streptomyces avermitilis MA-4680 1211905 NP_821331.1 CDS SAV_157 NC_003155.4 177538 179952 R PF06827: Zinc finger found in FPG and IleRS; hypothetical protein complement(177538..179952) Streptomyces avermitilis MA-4680 1211906 NP_821332.1 CDS SAV_158 NC_003155.4 179949 180287 R hypothetical protein complement(179949..180287) Streptomyces avermitilis MA-4680 1211907 NP_821333.1 CDS int1 NC_003155.4 180284 181426 R PF00589: Phage integrase family; integrase/recombinase complement(180284..181426) Streptomyces avermitilis MA-4680 1211908 NP_821334.1 CDS SAV_160 NC_003155.4 181802 182389 D hypothetical protein 181802..182389 Streptomyces avermitilis MA-4680 1211909 NP_821335.1 CDS SAV_161 NC_003155.4 182430 182948 D hypothetical protein 182430..182948 Streptomyces avermitilis MA-4680 1211910 NP_821336.1 CDS SAV_162 NC_003155.4 182945 183952 D hypothetical protein 182945..183952 Streptomyces avermitilis MA-4680 1211911 NP_821337.1 CDS SAV_163 NC_003155.4 184316 184795 D hypothetical protein 184316..184795 Streptomyces avermitilis MA-4680 1211912 NP_821338.1 CDS SAV_164 NC_003155.4 185138 185368 R hypothetical protein complement(185138..185368) Streptomyces avermitilis MA-4680 1211913 NP_821339.1 CDS SAV_165 NC_003155.4 185890 186507 D hypothetical protein 185890..186507 Streptomyces avermitilis MA-4680 1211914 NP_821340.1 CDS SAV_166 NC_003155.4 186549 186905 D hypothetical protein 186549..186905 Streptomyces avermitilis MA-4680 1211915 NP_821341.1 CDS SAV_167 NC_003155.4 187026 187742 D hypothetical protein 187026..187742 Streptomyces avermitilis MA-4680 1211916 NP_821342.1 CDS SAV_168 NC_003155.4 188180 189094 D hypothetical protein 188180..189094 Streptomyces avermitilis MA-4680 1211917 NP_821343.1 CDS SAV_169 NC_003155.4 188910 189866 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(188910..189866) Streptomyces avermitilis MA-4680 1211918 NP_821344.1 CDS SAV_170 NC_003155.4 190026 191453 R hypothetical protein complement(190026..191453) Streptomyces avermitilis MA-4680 1211919 NP_821345.1 CDS SAV_171 NC_003155.4 191479 192900 R hypothetical protein complement(191479..192900) Streptomyces avermitilis MA-4680 1211920 NP_821346.1 CDS SAV_172 NC_003155.4 193615 194553 D hypothetical protein 193615..194553 Streptomyces avermitilis MA-4680 1211921 NP_821347.1 CDS SAV_173 NC_003155.4 194571 194891 D hypothetical protein 194571..194891 Streptomyces avermitilis MA-4680 1211922 NP_821348.1 CDS SAV_174 NC_003155.4 194888 195463 D hypothetical protein 194888..195463 Streptomyces avermitilis MA-4680 1211923 NP_821349.1 CDS SAV_175 NC_003155.4 195460 198141 D ATP/GTP-binding protein 195460..198141 Streptomyces avermitilis MA-4680 1211924 NP_821350.1 CDS SAV_176 NC_003155.4 198138 198488 D hypothetical protein 198138..198488 Streptomyces avermitilis MA-4680 1211925 NP_821351.1 CDS SAV_177 NC_003155.4 198490 201222 D PF01970: Integral membrane protein DUF112; hypothetical protein 198490..201222 Streptomyces avermitilis MA-4680 1211926 NP_821352.1 CDS SAV_178 NC_003155.4 201219 202370 D Seems to have a cleavable N-term signal sequence; NLP/P60-family protein 201219..202370 Streptomyces avermitilis MA-4680 1211927 NP_821353.1 CDS SAV_179 NC_003155.4 202367 203014 D hypothetical protein 202367..203014 Streptomyces avermitilis MA-4680 1211928 NP_821354.1 CDS SAV_180 NC_003155.4 203056 205614 D ATP/GTP-binding protein 203056..205614 Streptomyces avermitilis MA-4680 1211929 NP_821355.1 CDS SAV_181 NC_003155.4 205611 206525 D hypothetical protein 205611..206525 Streptomyces avermitilis MA-4680 1211930 NP_821356.1 CDS SAV_182 NC_003155.4 207837 208697 D hypothetical protein 207837..208697 Streptomyces avermitilis MA-4680 1211931 NP_821357.1 CDS SAV_183 NC_003155.4 208719 209423 D hypothetical protein 208719..209423 Streptomyces avermitilis MA-4680 1211932 NP_821358.1 CDS SAV_184 NC_003155.4 209423 210250 D hypothetical protein 209423..210250 Streptomyces avermitilis MA-4680 1211933 NP_821359.1 CDS SAV_185 NC_003155.4 210240 211733 D PF00437: Type II/IV secretion system protein; ATP/GTP-binding protein 210240..211733 Streptomyces avermitilis MA-4680 1211934 NP_821360.1 CDS SAV_186 NC_003155.4 211730 212659 D PF00482: Bacterial type II secretion system protein F domain; integral membrane protein 211730..212659 Streptomyces avermitilis MA-4680 1211935 NP_821361.1 CDS SAV_187 NC_003155.4 212678 213562 D PF00482: Bacterial type II secretion system protein F domain; integral membrane protein 212678..213562 Streptomyces avermitilis MA-4680 1211936 NP_821362.1 CDS SAV_188 NC_003155.4 213608 213823 D hypothetical protein 213608..213823 Streptomyces avermitilis MA-4680 1211937 NP_821363.1 CDS SAV_189 NC_003155.4 213820 214248 D hypothetical protein 213820..214248 Streptomyces avermitilis MA-4680 1211938 NP_821364.1 CDS SAV_190 NC_003155.4 214245 214706 D hypothetical protein 214245..214706 Streptomyces avermitilis MA-4680 1211939 NP_821365.1 CDS SAV_191 NC_003155.4 214706 215158 D hypothetical protein 214706..215158 Streptomyces avermitilis MA-4680 1211940 NP_821366.1 CDS SAV_192 NC_003155.4 215158 218625 D PF01476: LysM domain; hypothetical protein 215158..218625 Streptomyces avermitilis MA-4680 1211941 NP_821367.1 CDS SAV_193 NC_003155.4 218903 220732 D hypothetical protein 218903..220732 Streptomyces avermitilis MA-4680 1211942 NP_821368.1 CDS SAV_194 NC_003155.4 220848 221402 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(220848..221402) Streptomyces avermitilis MA-4680 1211943 NP_821369.1 CDS SAV_195 NC_003155.4 221399 222835 R PF06036: Streptomyces protein of unknown function (DUF921); hypothetical protein complement(221399..222835) Streptomyces avermitilis MA-4680 1211944 NP_821370.1 CDS SAV_196 NC_003155.4 222871 224691 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein 222871..224691 Streptomyces avermitilis MA-4680 1211945 NP_821371.1 CDS SAV_197 NC_003155.4 225238 226227 D hypothetical protein 225238..226227 Streptomyces avermitilis MA-4680 1211946 NP_821372.1 CDS SAV_198 NC_003155.4 226312 227820 D amino acid/metabolite permease 226312..227820 Streptomyces avermitilis MA-4680 1211947 NP_821373.1 CDS SAV_199 NC_003155.4 227817 228737 D glutamine synthetase 227817..228737 Streptomyces avermitilis MA-4680 1211948 NP_821374.1 CDS SAV_200 NC_003155.4 229825 236937 R PF05593: RHS Repeat; large protein complement(229825..236937) Streptomyces avermitilis MA-4680 1211949 NP_821375.1 CDS SAV_201 NC_003155.4 237437 237682 D hypothetical protein 237437..237682 Streptomyces avermitilis MA-4680 1211950 NP_821376.1 CDS SAV_202 NC_003155.4 237840 238601 R hypothetical protein complement(237840..238601) Streptomyces avermitilis MA-4680 1211951 NP_821377.1 CDS SAV_203 NC_003155.4 239037 239462 R hypothetical protein complement(239037..239462) Streptomyces avermitilis MA-4680 1211952 NP_821378.1 CDS SAV_204 NC_003155.4 239788 240234 R hypothetical protein complement(239788..240234) Streptomyces avermitilis MA-4680 1211953 NP_821379.1 CDS SAV_205 NC_003155.4 240325 240903 D TetR family transcriptional regulator 240325..240903 Streptomyces avermitilis MA-4680 1211954 NP_821380.1 CDS SAV_206 NC_003155.4 241742 241966 R Tn4561 family, truncated; Tn4561 family transposase complement(241742..241966) Streptomyces avermitilis MA-4680 1211955 NP_821381.1 CDS SAV_207 NC_003155.4 241989 242195 R truncated; transposase complement(241989..242195) Streptomyces avermitilis MA-4680 1211956 NP_821382.1 CDS SAV_208 NC_003155.4 242908 243411 R IstB-like ATP-binding protein complement(242908..243411) Streptomyces avermitilis MA-4680 1211957 NP_821383.1 CDS SAV_209 NC_003155.4 243581 244771 R IS110 family transposase complement(243581..244771) Streptomyces avermitilis MA-4680 1211958 NP_821384.1 CDS SAV_210 NC_003155.4 245081 246040 R regulatory protein complement(245081..246040) Streptomyces avermitilis MA-4680 1211959 NP_821385.1 CDS SAV_211 NC_003155.4 246027 246653 R hypothetical protein complement(246027..246653) Streptomyces avermitilis MA-4680 1211960 NP_821386.1 CDS SAV_212 NC_003155.4 247471 248142 R hypothetical protein complement(247471..248142) Streptomyces avermitilis MA-4680 1211961 NP_821387.1 CDS sig60 NC_003155.4 248139 248741 R probably pseudogene; ECF subfamily RNA polymerase sigma factor complement(248139..248741) Streptomyces avermitilis MA-4680 1211962 NP_821388.1 CDS SAV_214 NC_003155.4 249173 249661 R hypothetical protein complement(249173..249661) Streptomyces avermitilis MA-4680 1211963 NP_821389.1 CDS SAV_215 NC_003155.4 249733 253416 R PF05729: NACHT domain; hypothetical protein complement(249733..253416) Streptomyces avermitilis MA-4680 1211964 NP_821390.1 CDS SAV_216 NC_003155.4 254011 254895 R PF03819: MazG nucleotide pyrophosphohydrolase domain; pyrophosphatase complement(254011..254895) Streptomyces avermitilis MA-4680 1211965 NP_821391.1 CDS fabC4 NC_003155.4 255013 255273 D PF00550: Phosphopantetheine attachment site; ACP 255013..255273 Streptomyces avermitilis MA-4680 1211966 NP_821392.1 CDS SAV_218 NC_003155.4 255270 255677 D transcriptional regulator 255270..255677 Streptomyces avermitilis MA-4680 1211967 NP_821393.1 CDS SAV_219 NC_003155.4 255674 256570 D PF06114 :Domain of unknown function (DUF955); hypothetical protein 255674..256570 Streptomyces avermitilis MA-4680 1211968 NP_821394.1 CDS SAV_220 NC_003155.4 256598 257401 D hypothetical protein 256598..257401 Streptomyces avermitilis MA-4680 1211969 NP_821395.1 CDS SAV_221 NC_003155.4 257443 258474 R hypothetical protein complement(257443..258474) Streptomyces avermitilis MA-4680 1211970 NP_821396.1 CDS SAV_222 NC_003155.4 258522 258809 D hypothetical protein 258522..258809 Streptomyces avermitilis MA-4680 1211971 NP_821397.1 CDS SAV_223 NC_003155.4 260024 261079 D PF03457: Helicase associated domain; DNA-binding protein 260024..261079 Streptomyces avermitilis MA-4680 1211972 NP_821398.1 CDS SAV_224 NC_003155.4 261139 262191 D hypothetical protein 261139..262191 Streptomyces avermitilis MA-4680 1211973 NP_821399.1 CDS SAV_225 NC_003155.4 263244 264521 R IS6120-like transposase complement(263244..264521) Streptomyces avermitilis MA-4680 1211974 NP_821400.1 CDS SAV_226 NC_003155.4 264551 266317 R PF00078: Reverse transcriptase (RNA-dependent DNA polymerase); reverse transcriptase complement(264551..266317) Streptomyces avermitilis MA-4680 1211975 NP_821401.1 CDS SAV_227 NC_003155.4 266680 268044 D similar to IS 4-family transposase; transposase 266680..268044 Streptomyces avermitilis MA-4680 1211976 NP_821402.1 CDS SAV_228 NC_003155.4 268251 269444 D hypothetical protein 268251..269444 Streptomyces avermitilis MA-4680 1211977 NP_821403.1 CDS SAV_229 NC_003155.4 269776 270012 D transposase 269776..270012 Streptomyces avermitilis MA-4680 1211978 NP_821404.1 CDS SAV_230 NC_003155.4 270055 271758 R PF05935: Arylsulfotransferase (ASST); hypothetical protein complement(270055..271758) Streptomyces avermitilis MA-4680 1211979 NP_821405.1 CDS SAV_231 NC_003155.4 272429 273277 R MerR family transcriptional regulator complement(272429..273277) Streptomyces avermitilis MA-4680 1211980 NP_821406.1 CDS SAV_232 NC_003155.4 273444 273962 R hypothetical protein complement(273444..273962) Streptomyces avermitilis MA-4680 1211981 NP_821407.1 CDS SAV_233 NC_003155.4 274210 274494 R hypothetical protein complement(274210..274494) Streptomyces avermitilis MA-4680 1211982 NP_821408.1 CDS SAV_234 NC_003155.4 274689 275168 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; regulatory protein complement(274689..275168) Streptomyces avermitilis MA-4680 1211983 NP_821409.1 CDS SAV_235 NC_003155.4 275233 275721 D PF01740: STAS domain; anti-sigma factor antagonist 275233..275721 Streptomyces avermitilis MA-4680 1211984 NP_821410.1 CDS SAV_236 NC_003155.4 275872 276393 D hypothetical protein 275872..276393 Streptomyces avermitilis MA-4680 1211985 NP_821411.1 CDS SAV_237 NC_003155.4 276877 278016 D DNA-binding protein 276877..278016 Streptomyces avermitilis MA-4680 1211986 NP_821412.1 CDS SAV_238 NC_003155.4 278037 278444 D DNA-binding protein 278037..278444 Streptomyces avermitilis MA-4680 1211987 NP_821413.1 CDS SAV_239 NC_003155.4 278470 279057 R hypothetical protein complement(278470..279057) Streptomyces avermitilis MA-4680 1211988 NP_821414.1 CDS SAV_240 NC_003155.4 279267 279635 R hypothetical protein complement(279267..279635) Streptomyces avermitilis MA-4680 1211989 NP_821415.1 CDS SAV_241 NC_003155.4 279644 279919 R PF03869: Arc-like DNA binding domain; hypothetical protein complement(279644..279919) Streptomyces avermitilis MA-4680 1211990 NP_821416.1 CDS SAV_242 NC_003155.4 280342 280782 R hypothetical protein complement(280342..280782) Streptomyces avermitilis MA-4680 1211991 NP_821417.1 CDS SAV_243 NC_003155.4 281208 281585 R hypothetical protein complement(281208..281585) Streptomyces avermitilis MA-4680 1211992 NP_821418.1 CDS SAV_244 NC_003155.4 281928 282242 D MerR family transcriptional regulator 281928..282242 Streptomyces avermitilis MA-4680 1211993 NP_821419.1 CDS SAV_245 NC_003155.4 282829 283503 R PF01810: LysE type translocator; LysE family efflux protein complement(282829..283503) Streptomyces avermitilis MA-4680 1211994 NP_821420.1 CDS SAV_246 NC_003155.4 283694 284041 R hypothetical protein complement(283694..284041) Streptomyces avermitilis MA-4680 1211995 NP_821421.1 CDS SAV_247 NC_003155.4 284429 286645 D PF05729: NACHT domain; hypothetical protein 284429..286645 Streptomyces avermitilis MA-4680 1211996 NP_821422.1 CDS SAV_248 NC_003155.4 287461 287775 R hypothetical protein complement(287461..287775) Streptomyces avermitilis MA-4680 1211997 NP_821423.1 CDS SAV_249 NC_003155.4 288173 288562 R hypothetical protein complement(288173..288562) Streptomyces avermitilis MA-4680 1211998 NP_821424.1 CDS SAV_250 NC_003155.4 288726 292160 D PF00515: TPR Domain; hypothetical protein 288726..292160 Streptomyces avermitilis MA-4680 1211999 NP_821425.1 CDS SAV_251 NC_003155.4 292968 293723 R PF02355: Protein export membrane protein; integral membrane protein complement(292968..293723) Streptomyces avermitilis MA-4680 1212000 NP_821426.1 CDS SAV_252 NC_003155.4 294014 294610 D ABC transporter ATP-binding protein 294014..294610 Streptomyces avermitilis MA-4680 1212001 NP_821427.1 CDS SAV_253 NC_003155.4 294912 295244 D MutT-family protein 294912..295244 Streptomyces avermitilis MA-4680 1212002 NP_821428.1 CDS SAV_254 NC_003155.4 295675 296976 D Tn5741 family, truncated; Tn5741 family transposase 295675..296976 Streptomyces avermitilis MA-4680 1212003 NP_821429.1 CDS SAV_255 NC_003155.4 296991 298436 D PF01433: Peptidase family M1; metallopeptidase 296991..298436 Streptomyces avermitilis MA-4680 1212004 NP_821430.1 CDS SAV_256 NC_003155.4 298664 299872 D PF01609: Transposase DDE domain; transposase 298664..299872 Streptomyces avermitilis MA-4680 1212005 NP_821431.1 CDS SAV_257 NC_003155.4 299873 300469 R ABC transporter ATP-binding protein complement(299873..300469) Streptomyces avermitilis MA-4680 1212006 NP_821432.1 CDS SAV_258 NC_003155.4 300882 301145 R hypothetical protein complement(300882..301145) Streptomyces avermitilis MA-4680 1212007 NP_821433.1 CDS asnH1 NC_003155.4 301142 303052 R asparagine synthetase complement(301142..303052) Streptomyces avermitilis MA-4680 1212008 NP_821434.1 CDS SAV_260 NC_003155.4 303674 304072 D transposase 303674..304072 Streptomyces avermitilis MA-4680 1212009 NP_821435.1 CDS SAV_261 NC_003155.4 304104 304334 D hypothetical protein 304104..304334 Streptomyces avermitilis MA-4680 1212010 NP_821436.1 CDS SAV_262 NC_003155.4 304527 305000 D hypothetical protein 304527..305000 Streptomyces avermitilis MA-4680 1212011 NP_821437.1 CDS SAV_263 NC_003155.4 305311 306945 R IS6 family transposase complement(305311..306945) Streptomyces avermitilis MA-4680 1212012 NP_821438.1 CDS SAV_264 NC_003155.4 307092 309302 R hypothetical protein complement(307092..309302) Streptomyces avermitilis MA-4680 1212013 NP_821439.1 CDS SAV_265 NC_003155.4 309794 310207 D hypothetical protein 309794..310207 Streptomyces avermitilis MA-4680 1212014 NP_821440.1 CDS SAV_266 NC_003155.4 310455 311114 R hypothetical protein complement(310455..311114) Streptomyces avermitilis MA-4680 1212015 NP_821441.1 CDS SAV_267 NC_003155.4 311330 311680 D hypothetical protein 311330..311680 Streptomyces avermitilis MA-4680 1212016 NP_821442.1 CDS SAV_268 NC_003155.4 312030 312479 R hypothetical protein complement(312030..312479) Streptomyces avermitilis MA-4680 1212017 NP_821443.1 CDS SAV_269 NC_003155.4 312589 314877 R hypothetical protein complement(312589..314877) Streptomyces avermitilis MA-4680 1212018 NP_821444.1 CDS SAV_270 NC_003155.4 315325 315852 D hypothetical protein 315325..315852 Streptomyces avermitilis MA-4680 1212019 NP_821445.1 CDS SAV_271 NC_003155.4 317520 317873 R hypothetical protein complement(317520..317873) Streptomyces avermitilis MA-4680 1212020 NP_821446.1 CDS SAV_272 NC_003155.4 319056 320099 D hypothetical protein 319056..320099 Streptomyces avermitilis MA-4680 1212021 NP_821447.1 CDS SAV_273 NC_003155.4 320615 320959 D DNA invertase/recombinase 320615..320959 Streptomyces avermitilis MA-4680 1212022 NP_821448.1 CDS SAV_274 NC_003155.4 320979 321200 R IS630 family transposase complement(320979..321200) Streptomyces avermitilis MA-4680 1212023 NP_821449.1 CDS SAV_275 NC_003155.4 321655 322395 D PF06036: Streptomyces protein of unknown function (DUF921); hypothetical protein 321655..322395 Streptomyces avermitilis MA-4680 1212024 NP_821450.1 CDS SAV_276 NC_003155.4 322432 322938 D MutT-family protein 322432..322938 Streptomyces avermitilis MA-4680 1212025 NP_821451.1 CDS SAV_277 NC_003155.4 323014 323400 D hypothetical protein 323014..323400 Streptomyces avermitilis MA-4680 1212026 NP_821452.1 CDS SAV_278 NC_003155.4 323714 324121 R hypothetical protein complement(323714..324121) Streptomyces avermitilis MA-4680 1212027 NP_821453.1 CDS SAV_279 NC_003155.4 324309 325121 D PF02945: Recombination endonuclease VII; endonuclease 324309..325121 Streptomyces avermitilis MA-4680 1212028 NP_821454.1 CDS SAV_280 NC_003155.4 325362 325622 D hypothetical protein 325362..325622 Streptomyces avermitilis MA-4680 1212029 NP_821455.1 CDS SAV_281 NC_003155.4 325633 326067 D hypothetical protein 325633..326067 Streptomyces avermitilis MA-4680 1212030 NP_821456.1 CDS SAV_282 NC_003155.4 326189 326509 R hypothetical protein complement(326189..326509) Streptomyces avermitilis MA-4680 1212031 NP_821457.1 CDS SAV_283 NC_003155.4 326629 327654 D hypothetical protein 326629..327654 Streptomyces avermitilis MA-4680 1212032 NP_821458.1 CDS SAV_284 NC_003155.4 327842 327994 R hypothetical protein complement(327842..327994) Streptomyces avermitilis MA-4680 1212033 NP_821459.1 CDS SAV_285 NC_003155.4 328293 328691 D hypothetical protein 328293..328691 Streptomyces avermitilis MA-4680 1212034 NP_821460.1 CDS SAV_286 NC_003155.4 329452 336546 R PF05593: RHS Repeat; large protein complement(329452..336546) Streptomyces avermitilis MA-4680 1212035 NP_821461.1 CDS SAV_287 NC_003155.4 336652 337179 R IS630 family; IS630 family transposase complement(336652..337179) Streptomyces avermitilis MA-4680 1212036 NP_821462.1 CDS SAV_288 NC_003155.4 337203 337778 R IS630 family transposase complement(337203..337778) Streptomyces avermitilis MA-4680 1212037 NP_821463.1 CDS SAV_289 NC_003155.4 337911 339185 D IS4 family transposase 337911..339185 Streptomyces avermitilis MA-4680 1212038 NP_821464.1 CDS SAV_290 NC_003155.4 339271 339735 R IS3L-like transposase complement(339271..339735) Streptomyces avermitilis MA-4680 1212039 NP_821465.1 CDS SAV_291 NC_003155.4 339819 341939 R IS30 family; IS30 family transposase complement(339819..341939) Streptomyces avermitilis MA-4680 1212040 NP_821466.1 CDS SAV_292 NC_003155.4 343063 343689 D TetR family transcriptional regulator 343063..343689 Streptomyces avermitilis MA-4680 1212041 NP_821467.1 CDS SAV_293 NC_003155.4 343805 345154 R PF00175: Oxidoreductase NAD-binding domain; oxidoreductase complement(343805..345154) Streptomyces avermitilis MA-4680 1212042 NP_821468.1 CDS SAV_294 NC_003155.4 345361 345771 R invasion protein complement(345361..345771) Streptomyces avermitilis MA-4680 1212043 NP_821469.1 CDS SAV_295 NC_003155.4 345826 346056 R hypothetical protein complement(345826..346056) Streptomyces avermitilis MA-4680 1212044 NP_821470.1 CDS SAV_296 NC_003155.4 346092 347669 R PF01360: Monooxygenase; hypothetical protein complement(346092..347669) Streptomyces avermitilis MA-4680 1212045 NP_821471.1 CDS SAV_297 NC_003155.4 347666 348571 R PF00561: alpha/beta hydrolase fold; alpha/beta hydrolase complement(347666..348571) Streptomyces avermitilis MA-4680 1212046 NP_821472.1 CDS SAV_298 NC_003155.4 348591 349424 R PF00561: alpha/beta hydrolase fold; alpha/beta hydrolase complement(348591..349424) Streptomyces avermitilis MA-4680 1212047 NP_821473.1 CDS lipW NC_003155.4 349710 350726 D arylesterase/monoxygenase 349710..350726 Streptomyces avermitilis MA-4680 1212048 NP_821474.1 CDS SAV_300 NC_003155.4 351026 352264 R IS256 family transposase complement(351026..352264) Streptomyces avermitilis MA-4680 1212049 NP_821475.1 CDS SAV_301 NC_003155.4 352678 353949 D PF01609: Transposase DDE domain; hypothetical protein 352678..353949 Streptomyces avermitilis MA-4680 1212050 NP_821476.1 CDS SAV_302 NC_003155.4 354545 354832 D hypothetical protein 354545..354832 Streptomyces avermitilis MA-4680 1212051 NP_821477.1 CDS SAV_303 NC_003155.4 355009 356106 D IS116/IS110/IS902 family; IS110 family transposase 355009..356106 Streptomyces avermitilis MA-4680 1212052 NP_821478.1 CDS SAV_304 NC_003155.4 355951 357105 R hypothetical protein complement(355951..357105) Streptomyces avermitilis MA-4680 1212053 NP_821479.1 CDS SAV_305 NC_003155.4 357868 359805 D hypothetical protein 357868..359805 Streptomyces avermitilis MA-4680 1212054 NP_821480.1 CDS SAV_306 NC_003155.4 360375 361958 D transcriptional regulatory protein 360375..361958 Streptomyces avermitilis MA-4680 1212055 NP_821481.1 CDS SAV_307 NC_003155.4 362562 363170 D hypothetical protein 362562..363170 Streptomyces avermitilis MA-4680 1212056 NP_821482.1 CDS SAV_308 NC_003155.4 364046 364411 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(364046..364411) Streptomyces avermitilis MA-4680 1212057 NP_821483.1 CDS SAV_309 NC_003155.4 366810 368000 D PF07592: Rhodopirellula transposase; transposase 366810..368000 Streptomyces avermitilis MA-4680 1212058 NP_821484.1 CDS SAV_310 NC_003155.4 368148 368522 D transposase 368148..368522 Streptomyces avermitilis MA-4680 1212059 NP_821485.1 CDS SAV_311 NC_003155.4 368620 369621 R IS4 family, partial; IS4 family transposase complement(368620..369621) Streptomyces avermitilis MA-4680 1212060 NP_821486.2 CDS SAV_312 NC_003155.4 369344 370132 R IS4 family transposase complement(369344..370132) Streptomyces avermitilis MA-4680 1212061 YP_001621480.1 CDS SAV_7574 NC_003155.4 370323 370796 R IS630 family IS885-like transposase complement(370323..370796) Streptomyces avermitilis MA-4680 5815321 NP_821487.1 CDS SAV_313 NC_003155.4 371009 372637 R IS4 family transposase complement(371009..372637) Streptomyces avermitilis MA-4680 1212062 NP_821488.1 CDS SAV_314 NC_003155.4 372788 373066 D IS3 family transposase 372788..373066 Streptomyces avermitilis MA-4680 1212063 NP_821489.1 CDS SAV_315 NC_003155.4 373063 373980 D IS3 family transposase 373063..373980 Streptomyces avermitilis MA-4680 1212064 NP_821490.3 CDS SAV_316 NC_003155.4 374009 374506 R IS5 family, frame shift; IS630 family ISBs2-like transposase complement(374009..374506) Streptomyces avermitilis MA-4680 1212065 NP_821491.1 CDS SAV_317 NC_003155.4 374674 375582 R IS5 family; hypothetical protein complement(374674..375582) Streptomyces avermitilis MA-4680 1212066 NP_821492.2 CDS SAV_318 NC_003155.4 375668 376681 R IS5 family; hypothetical protein complement(375668..376681) Streptomyces avermitilis MA-4680 1212067 NP_821493.2 CDS SAV_319 NC_003155.4 376883 378157 D IS4 family transposase 376883..378157 Streptomyces avermitilis MA-4680 1212068 NP_821494.1 CDS SAV_320 NC_003155.4 378281 378862 R hypothetical protein complement(378281..378862) Streptomyces avermitilis MA-4680 1212069 NP_821495.1 CDS prpB1 NC_003155.4 379220 380458 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(379220..380458) Streptomyces avermitilis MA-4680 1212070 NP_821496.1 CDS SAV_322 NC_003155.4 380736 381536 R PF03006: Haemolysin-III related; hypothetical protein complement(380736..381536) Streptomyces avermitilis MA-4680 1212071 NP_821497.1 CDS SAV_323 NC_003155.4 381592 381924 R MerR family transcriptional regulator complement(381592..381924) Streptomyces avermitilis MA-4680 1212072 NP_821498.1 CDS SAV_324 NC_003155.4 383053 383349 R transcription regulator ArsR complement(383053..383349) Streptomyces avermitilis MA-4680 1212073 NP_821499.1 CDS SAV_325 NC_003155.4 383431 384198 R hypothetical protein complement(383431..384198) Streptomyces avermitilis MA-4680 1212074 NP_821500.1 CDS SAV_326 NC_003155.4 385228 385533 R PF03819: MazG nucleotide pyrophosphohydrolase domain; hypothetical protein complement(385228..385533) Streptomyces avermitilis MA-4680 1212075 NP_821501.1 CDS SAV_327 NC_003155.4 386051 386746 R hypothetical protein complement(386051..386746) Streptomyces avermitilis MA-4680 1212076 NP_821502.1 CDS SAV_328 NC_003155.4 386768 387076 D hypothetical protein 386768..387076 Streptomyces avermitilis MA-4680 1212077 NP_821503.1 CDS SAV_329 NC_003155.4 387129 387536 D hypothetical protein 387129..387536 Streptomyces avermitilis MA-4680 1212078 NP_821504.1 CDS SAV_330 NC_003155.4 387639 387947 R hypothetical protein complement(387639..387947) Streptomyces avermitilis MA-4680 1212079 NP_821505.1 CDS SAV_331 NC_003155.4 387951 388265 R hypothetical protein complement(387951..388265) Streptomyces avermitilis MA-4680 1212080 NP_821506.1 CDS SAV_333 NC_003155.4 388386 388766 R hypothetical protein complement(388386..388766) Streptomyces avermitilis MA-4680 1212081 NP_821507.1 CDS SAV_332 NC_003155.4 388722 388958 D hypothetical protein 388722..388958 Streptomyces avermitilis MA-4680 1212082 NP_821508.1 CDS SAV_334 NC_003155.4 389084 389704 D hypothetical protein 389084..389704 Streptomyces avermitilis MA-4680 1212083 NP_821509.1 CDS SAV_335 NC_003155.4 389694 391292 R hypothetical protein complement(389694..391292) Streptomyces avermitilis MA-4680 1212084 NP_821510.1 CDS SAV_336 NC_003155.4 391476 392177 R hypothetical protein complement(391476..392177) Streptomyces avermitilis MA-4680 1212085 NP_821511.1 CDS SAV_337 NC_003155.4 392309 393166 D hypothetical protein 392309..393166 Streptomyces avermitilis MA-4680 1212086 NP_821512.1 CDS SAV_338 NC_003155.4 393683 394816 R hypothetical protein complement(393683..394816) Streptomyces avermitilis MA-4680 1212087 NP_821513.1 CDS ldhA NC_003155.4 394813 395724 R PF00056: lactate/malate dehydrogenase, NAD binding domain; lactate dehydrogenase complement(394813..395724) Streptomyces avermitilis MA-4680 1210021 NP_821514.1 CDS SAV_340 NC_003155.4 395736 397091 R hypothetical protein complement(395736..397091) Streptomyces avermitilis MA-4680 1212088 NP_821515.1 CDS SAV_341 NC_003155.4 397379 397615 R hypothetical protein complement(397379..397615) Streptomyces avermitilis MA-4680 1212089 NP_821516.1 CDS SAV_342 NC_003155.4 397612 398019 R hypothetical protein complement(397612..398019) Streptomyces avermitilis MA-4680 1212090 NP_821517.1 CDS SAV_343 NC_003155.4 398215 399555 D PF06036: Streptomyces protein of unknown function (DUF921); regulatory protein 398215..399555 Streptomyces avermitilis MA-4680 1212091 NP_821518.1 CDS SAV_344 NC_003155.4 399603 400892 R PF06054: Competence protein CoiA-like family; hypothetical protein complement(399603..400892) Streptomyces avermitilis MA-4680 1212092 NP_821519.1 CDS SAV_345 NC_003155.4 401070 401894 D hypothetical protein 401070..401894 Streptomyces avermitilis MA-4680 1212093 NP_821520.1 CDS SAV_346 NC_003155.4 402923 404059 D hypothetical protein 402923..404059 Streptomyces avermitilis MA-4680 1212094 NP_821521.1 CDS SAV_347 NC_003155.4 404592 405830 R IS256 family transposase complement(404592..405830) Streptomyces avermitilis MA-4680 1212095 NP_821522.1 CDS katB NC_003155.4 406594 408870 D catalase 406594..408870 Streptomyces avermitilis MA-4680 1210022 NP_821523.1 CDS SAV_349 NC_003155.4 408998 409465 D hypothetical protein 408998..409465 Streptomyces avermitilis MA-4680 1212096 NP_821524.1 CDS prpD NC_003155.4 409830 411953 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(409830..411953) Streptomyces avermitilis MA-4680 1212097 NP_821525.1 CDS SAV_351 NC_003155.4 412866 413366 R hypothetical protein complement(412866..413366) Streptomyces avermitilis MA-4680 1212098 NP_821526.1 CDS SAV_352 NC_003155.4 413661 414347 D hypothetical protein 413661..414347 Streptomyces avermitilis MA-4680 1212099 NP_821527.1 CDS SAV_353 NC_003155.4 414815 416212 D hypothetical protein 414815..416212 Streptomyces avermitilis MA-4680 1212100 NP_821528.1 CDS SAV_354 NC_003155.4 416987 419176 D hypothetical protein 416987..419176 Streptomyces avermitilis MA-4680 1212101 NP_821529.1 CDS SAV_355 NC_003155.4 419179 420861 D PF00534: Glycosyl transferases group 1; glycosyltransferase 419179..420861 Streptomyces avermitilis MA-4680 1212102 NP_821530.1 CDS SAV_356 NC_003155.4 420855 422207 D hypothetical protein 420855..422207 Streptomyces avermitilis MA-4680 1212103 NP_821531.1 CDS galE4 NC_003155.4 422345 423352 D UDP-glucose 4-epimerase 422345..423352 Streptomyces avermitilis MA-4680 1210023 NP_821532.1 CDS mpg1 NC_003155.4 423399 424112 D mannose-1-phosphate guanyltransferase 423399..424112 Streptomyces avermitilis MA-4680 1210024 NP_821533.1 CDS SAV_359 NC_003155.4 424117 425016 D NDP-hexose 4-ketoreductase 424117..425016 Streptomyces avermitilis MA-4680 1212104 NP_821534.1 CDS SAV_360 NC_003155.4 425013 425681 D hypothetical protein 425013..425681 Streptomyces avermitilis MA-4680 1212105 NP_821535.1 CDS SAV_361 NC_003155.4 425823 426356 D hypothetical protein 425823..426356 Streptomyces avermitilis MA-4680 1212106 NP_821536.1 CDS SAV_362 NC_003155.4 426615 427010 R hypothetical protein complement(426615..427010) Streptomyces avermitilis MA-4680 1212107 NP_821537.1 CDS SAV_363 NC_003155.4 427297 428631 R hypothetical protein complement(427297..428631) Streptomyces avermitilis MA-4680 1212108 NP_821538.1 CDS SAV_364 NC_003155.4 428654 429688 R IS116/IS110/IS902 family; IS110 family transposase complement(428654..429688) Streptomyces avermitilis MA-4680 1212109 NP_821539.1 CDS SAV_365 NC_003155.4 430053 431681 D IS4 family transposase 430053..431681 Streptomyces avermitilis MA-4680 1212110 NP_821540.1 CDS SAV_366 NC_003155.4 432038 434323 D hypothetical protein 432038..434323 Streptomyces avermitilis MA-4680 1212111 NP_821541.1 CDS helZ1 NC_003155.4 434410 437262 D SNF2/RAD54 family helicase 434410..437262 Streptomyces avermitilis MA-4680 1210025 NP_821542.1 CDS SAV_368 NC_003155.4 437259 438503 D PF04434: SWIM zinc finger; hypothetical protein 437259..438503 Streptomyces avermitilis MA-4680 1212112 NP_821543.1 CDS SAV_369 NC_003155.4 438792 439298 D hypothetical protein 438792..439298 Streptomyces avermitilis MA-4680 1212113 NP_821544.1 CDS int2 NC_003155.4 439342 439959 R PF00589: Phage integrase family; integrase complement(439342..439959) Streptomyces avermitilis MA-4680 1212114 NP_821545.1 CDS SAV_371 NC_003155.4 439970 440566 R PF03807: NADP oxidoreductase coenzyme F420-dependent; oxidoreductase complement(439970..440566) Streptomyces avermitilis MA-4680 1212115 NP_821546.1 CDS suhB2 NC_003155.4 440608 441426 R PF00459: Inositol monophosphatase family; myo-inositol 1-monophosphatase complement(440608..441426) Streptomyces avermitilis MA-4680 1212116 NP_821547.1 CDS SAV_373 NC_003155.4 441565 442470 D LysR family transcriptional regulator 441565..442470 Streptomyces avermitilis MA-4680 1212117 NP_821548.1 CDS SAV_374 NC_003155.4 443421 443774 D hypothetical protein 443421..443774 Streptomyces avermitilis MA-4680 1212118 NP_821549.1 CDS SAV_375 NC_003155.4 444076 444585 D IS200/IS605 family; IS200-like transposase 444076..444585 Streptomyces avermitilis MA-4680 1212119 NP_821550.1 CDS SAV_376 NC_003155.4 444528 445748 R PF02954: Bacterial regulatory protein, Fis family; hypothetical protein complement(444528..445748) Streptomyces avermitilis MA-4680 1212120 NP_821551.1 CDS fadD1 NC_003155.4 445913 447400 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase 445913..447400 Streptomyces avermitilis MA-4680 1210026 NP_821552.1 CDS SAV_378 NC_003155.4 448119 448310 R Tn5741 family, truncated; Tn5741 family transposase complement(448119..448310) Streptomyces avermitilis MA-4680 1212121 NP_821553.1 CDS SAV_379 NC_003155.4 449403 449558 R hypothetical protein complement(449403..449558) Streptomyces avermitilis MA-4680 1212122 NP_821554.1 CDS SAV_380 NC_003155.4 449586 452924 R hypothetical protein complement(449586..452924) Streptomyces avermitilis MA-4680 1212123 NP_821555.1 CDS SAV_381 NC_003155.4 453216 454730 D PF04984: Phage tail sheath protein; phage tail sheath protein 453216..454730 Streptomyces avermitilis MA-4680 1212124 NP_821556.1 CDS SAV_382 NC_003155.4 454732 455262 D hypothetical protein 454732..455262 Streptomyces avermitilis MA-4680 1212125 NP_821557.1 CDS SAV_383 NC_003155.4 455295 456008 D hypothetical protein 455295..456008 Streptomyces avermitilis MA-4680 1212126 NP_821558.1 CDS SAV_384 NC_003155.4 456005 456901 D hypothetical protein 456005..456901 Streptomyces avermitilis MA-4680 1212127 NP_821559.1 CDS SAV_385 NC_003155.4 456898 458088 D hypothetical protein 456898..458088 Streptomyces avermitilis MA-4680 1212128 NP_821560.1 CDS SAV_386 NC_003155.4 458085 459584 D hypothetical protein 458085..459584 Streptomyces avermitilis MA-4680 1212129 NP_821561.1 CDS SAV_387 NC_003155.4 459466 460251 D PF00004: ATPase family associated with various cellular activities (AAA); ATPase AAA 459466..460251 Streptomyces avermitilis MA-4680 1212130 NP_821562.1 CDS SAV_388 NC_003155.4 460571 461251 D hypothetical protein 460571..461251 Streptomyces avermitilis MA-4680 1212131 NP_821563.1 CDS SAV_389 NC_003155.4 461251 461568 D hypothetical protein 461251..461568 Streptomyces avermitilis MA-4680 1212132 NP_821564.1 CDS SAV_390 NC_003155.4 461558 462664 D hypothetical protein 461558..462664 Streptomyces avermitilis MA-4680 1212133 NP_821565.1 CDS SAV_391 NC_003155.4 462705 463295 D hypothetical protein 462705..463295 Streptomyces avermitilis MA-4680 1212134 NP_821566.1 CDS SAV_392 NC_003155.4 463306 463653 D hypothetical protein 463306..463653 Streptomyces avermitilis MA-4680 1212135 NP_821567.1 CDS SAV_393 NC_003155.4 463650 464039 D PF04965: GPW / gp25 family; hypothetical protein 463650..464039 Streptomyces avermitilis MA-4680 1212136 NP_821568.1 CDS SAV_394 NC_003155.4 464036 466855 D hypothetical protein 464036..466855 Streptomyces avermitilis MA-4680 1212137 NP_821569.1 CDS SAV_395 NC_003155.4 466862 469465 D hypothetical protein 466862..469465 Streptomyces avermitilis MA-4680 1212138 NP_821570.1 CDS SAV_396 NC_003155.4 469462 471561 D hypothetical protein 469462..471561 Streptomyces avermitilis MA-4680 1212139 NP_821571.1 CDS SAV_397 NC_003155.4 471571 472863 D hypothetical protein 471571..472863 Streptomyces avermitilis MA-4680 1212140 NP_821572.1 CDS SAV_398 NC_003155.4 472897 474789 D hypothetical protein 472897..474789 Streptomyces avermitilis MA-4680 1212141 NP_821573.1 CDS SAV_399 NC_003155.4 474824 475045 R hypothetical protein complement(474824..475045) Streptomyces avermitilis MA-4680 1212142 NP_821574.1 CDS SAV_400 NC_003155.4 475108 475824 R PF03704: Bacterial transcriptional activator domain; transcriptional regulator complement(475108..475824) Streptomyces avermitilis MA-4680 1212143 NP_821575.1 CDS SAV_401 NC_003155.4 476025 478859 D LuxR family transcriptional regulator 476025..478859 Streptomyces avermitilis MA-4680 1212144 NP_821576.1 CDS SAV_402 NC_003155.4 479076 479630 R hypothetical protein complement(479076..479630) Streptomyces avermitilis MA-4680 1212145 NP_821577.1 CDS pntB NC_003155.4 479883 481349 R pyridine nucleotide transhydrogenase, beta subunit complement(479883..481349) Streptomyces avermitilis MA-4680 1210027 NP_821578.1 CDS pntA NC_003155.4 481356 482912 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(481356..482912) Streptomyces avermitilis MA-4680 1210028 NP_821579.1 CDS SAV_405 NC_003155.4 484188 484907 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 484188..484907 Streptomyces avermitilis MA-4680 1212146 NP_821580.1 CDS SAV_406 NC_003155.4 484941 485378 D PF00293: NUDIX domain; hypothetical protein 484941..485378 Streptomyces avermitilis MA-4680 1212147 NP_821581.1 CDS SAV_7575 NC_003155.4 485375 485860 D dipeptidase 485375..485860 Streptomyces avermitilis MA-4680 1212148 NP_821582.1 CDS pteH NC_003155.4 486648 487415 R filipin gene cluster; thioesterase complement(486648..487415) Streptomyces avermitilis MA-4680 1210029 NP_821583.1 CDS pteG NC_003155.4 487512 489155 R filipin gene cluster, PF05199: GMC oxidoreductase; cholesterol oxidase complement(487512..489155) Streptomyces avermitilis MA-4680 1210030 NP_821584.1 CDS pteF NC_003155.4 489621 490319 R filipin gene cluster; LuxR family transcriptional regulator complement(489621..490319) Streptomyces avermitilis MA-4680 1210031 NP_821585.1 CDS pteR NC_003155.4 490902 494192 D filipin gene cluster, PF06498: Adenylate cyclase associated, PF03704: Bacterial transcriptional activator domain; DnrI/RedD/AfsR family transcriptional regulator 490902..494192 Streptomyces avermitilis MA-4680 1210032 NP_821586.1 CDS pteE NC_003155.4 494248 494442 R fdxI, filipin gene cluster; ferredoxin complement(494248..494442) Streptomyces avermitilis MA-4680 1210033 NP_821587.1 CDS pteD NC_003155.4 494487 495737 R CYP105D6, fdxI is located at downstream, filipin gene cluster; cytochrome P450 hydroxylase complement(494487..495737) Streptomyces avermitilis MA-4680 1210034 NP_821588.1 CDS pteC NC_003155.4 496283 497482 R CYP105P1, filipin gene cluster; cytochrome P450 hydroxylase complement(496283..497482) Streptomyces avermitilis MA-4680 1210035 NP_821589.1 CDS pteB NC_003155.4 497529 498785 R filipin gene cluster, PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(497529..498785) Streptomyces avermitilis MA-4680 1210036 NP_821590.1 CDS pteA5 NC_003155.4 498846 508904 R filipin gene cluster; modular polyketide synthase complement(498846..508904) Streptomyces avermitilis MA-4680 1210037 NP_821591.1 CDS pteA4 NC_003155.4 508951 527388 R filipin gene cluster; modular polyketide synthase complement(508951..527388) Streptomyces avermitilis MA-4680 1210038 NP_821592.1 CDS pteA3 NC_003155.4 527468 532975 R filipin gene cluster; modular polyketide synthase complement(527468..532975) Streptomyces avermitilis MA-4680 1210039 NP_821593.1 CDS pteA2 NC_003155.4 533011 543705 R filipin gene cluster; modular polyketide synthase complement(533011..543705) Streptomyces avermitilis MA-4680 1210040 NP_821594.1 CDS pteA1 NC_003155.4 543777 567017 R filipin gene cluster; modular polyketide synthase complement(543777..567017) Streptomyces avermitilis MA-4680 1210041 NP_821595.1 CDS SAV_420 NC_003155.4 567663 568697 D PF01526: Transposase; transposase 567663..568697 Streptomyces avermitilis MA-4680 1212149 NP_821596.1 CDS SAV_421 NC_003155.4 568699 569952 D PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein 568699..569952 Streptomyces avermitilis MA-4680 1212150 NP_821597.1 CDS SAV_422 NC_003155.4 570215 570763 R hypothetical protein complement(570215..570763) Streptomyces avermitilis MA-4680 1212151 NP_821598.1 CDS SAV_423 NC_003155.4 570940 571578 D IS30 family, partial; IS30 family transposase 570940..571578 Streptomyces avermitilis MA-4680 1212152 YP_187527.1 CDS SAV_7576 NC_003155.4 571598 571915 D IS3 family, partial; IS3 family transposase 571598..571915 Streptomyces avermitilis MA-4680 3238945 NP_821599.1 CDS sig3 NC_003155.4 573907 574845 R ECF subfamily RNA polymerase sigma factor complement(573907..574845) Streptomyces avermitilis MA-4680 1210042 NP_821600.1 CDS SAV_425 NC_003155.4 574856 576046 R PF00070: Pyridine nucleotide-disulphide oxidoreductase; oxidoreductase complement(574856..576046) Streptomyces avermitilis MA-4680 1212153 NP_821601.1 CDS SAV_426 NC_003155.4 576232 576603 R hypothetical protein complement(576232..576603) Streptomyces avermitilis MA-4680 1212154 NP_821602.1 CDS SAV_427 NC_003155.4 576830 577165 R hypothetical protein complement(576830..577165) Streptomyces avermitilis MA-4680 1212155 NP_821603.1 CDS SAV_428 NC_003155.4 577719 578180 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(577719..578180) Streptomyces avermitilis MA-4680 1212156 NP_821604.1 CDS SAV_429 NC_003155.4 579136 579753 D PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein 579136..579753 Streptomyces avermitilis MA-4680 1212157 NP_821605.1 CDS SAV_430 NC_003155.4 579746 580549 D PF00106: short chain dehydrogenase; dehydrogenase 579746..580549 Streptomyces avermitilis MA-4680 1212158 NP_821606.1 CDS SAV_431 NC_003155.4 580610 581254 R TetR family transcriptional regulator complement(580610..581254) Streptomyces avermitilis MA-4680 1212159 NP_821607.1 CDS SAV_432 NC_003155.4 581626 582858 D PF02415: Chlamydia polymorphic membrane protein (Chlamydia_PMP); hypothetical protein 581626..582858 Streptomyces avermitilis MA-4680 1212160 NP_821608.1 CDS SAV_433 NC_003155.4 582893 584755 D PF00135: Carboxylesterase; carboxylesterase 582893..584755 Streptomyces avermitilis MA-4680 1212161 NP_821609.1 CDS SAV_434 NC_003155.4 584755 585144 D hypothetical protein 584755..585144 Streptomyces avermitilis MA-4680 1212162 NP_821610.1 CDS SAV_435 NC_003155.4 585449 585874 D hypothetical protein 585449..585874 Streptomyces avermitilis MA-4680 1212163 NP_821611.1 CDS SAV_436 NC_003155.4 585858 586517 R TetR family transcriptional regulator complement(585858..586517) Streptomyces avermitilis MA-4680 1212164 NP_821612.1 CDS prpM1 NC_003155.4 587625 590051 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(587625..590051) Streptomyces avermitilis MA-4680 1212165 NP_821613.1 CDS SAV_438 NC_003155.4 590678 591778 R hypothetical protein complement(590678..591778) Streptomyces avermitilis MA-4680 1212166 NP_821614.1 CDS SAV_439 NC_003155.4 592072 592773 R hypothetical protein complement(592072..592773) Streptomyces avermitilis MA-4680 1212167 NP_821615.1 CDS rpoA2 NC_003155.4 594232 595248 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 594232..595248 Streptomyces avermitilis MA-4680 1210043 NP_821616.1 CDS SAV_441 NC_003155.4 595471 596031 D IS3L-like transposase 595471..596031 Streptomyces avermitilis MA-4680 1212168 NP_821617.1 CDS SAV_442 NC_003155.4 596538 596843 D hypothetical protein 596538..596843 Streptomyces avermitilis MA-4680 1212169 NP_821618.1 CDS SAV_443 NC_003155.4 596972 597148 D hypothetical protein 596972..597148 Streptomyces avermitilis MA-4680 1212170 NP_821619.1 CDS wapA NC_003155.4 598312 600774 R PF05593: RHS Repeat; cell wall-associated protein complement(598312..600774) Streptomyces avermitilis MA-4680 1212171 NP_821620.1 CDS SAV_445 NC_003155.4 601030 601425 R Tn4561 family, truncated; Tn4561 family transposase complement(601030..601425) Streptomyces avermitilis MA-4680 1212172 NP_821621.1 CDS SAV_446 NC_003155.4 601349 601615 R IS630 family, truncated; IS630 family transposase complement(601349..601615) Streptomyces avermitilis MA-4680 1212173 NP_821622.1 CDS SAV_447 NC_003155.4 601641 601862 D IS630 family, truncated; IS630 family transposase 601641..601862 Streptomyces avermitilis MA-4680 1212174 NP_821623.1 CDS SAV_448 NC_003155.4 602829 603446 R TetR family transcriptional regulator complement(602829..603446) Streptomyces avermitilis MA-4680 1212175 NP_821624.1 CDS SAV_449 NC_003155.4 603569 603973 D hypothetical protein 603569..603973 Streptomyces avermitilis MA-4680 1212176 NP_821625.1 CDS SAV_450 NC_003155.4 604002 604904 D hypothetical protein 604002..604904 Streptomyces avermitilis MA-4680 1212177 NP_821626.1 CDS bldG NC_003155.4 605005 605373 R PF01740: STAS domain; anti-sigma factor antagonist complement(605005..605373) Streptomyces avermitilis MA-4680 1210044 NP_821627.1 CDS SAV_452 NC_003155.4 605510 606031 D hypothetical protein 605510..606031 Streptomyces avermitilis MA-4680 1212178 NP_821628.1 CDS SAV_453 NC_003155.4 606058 606540 D hypothetical protein 606058..606540 Streptomyces avermitilis MA-4680 1212179 NP_821629.1 CDS SAV_454 NC_003155.4 606685 607839 D hypothetical protein 606685..607839 Streptomyces avermitilis MA-4680 1212180 NP_821630.1 CDS SAV_455 NC_003155.4 607861 608373 R hypothetical protein complement(607861..608373) Streptomyces avermitilis MA-4680 1212181 NP_821631.1 CDS SAV_456 NC_003155.4 608423 609064 D hypothetical protein 608423..609064 Streptomyces avermitilis MA-4680 1212182 NP_821632.1 CDS SAV_457 NC_003155.4 609036 610703 R PF04434: SWIM zinc finger; hypothetical protein complement(609036..610703) Streptomyces avermitilis MA-4680 1212183 NP_821633.1 CDS SAV_458 NC_003155.4 611754 612434 R hsp18 transcriptional regulator complement(611754..612434) Streptomyces avermitilis MA-4680 1212184 NP_821634.1 CDS hspX NC_003155.4 612565 612999 D PF00011: Hsp20/alpha crystallin family; heat shock protein 612565..612999 Streptomyces avermitilis MA-4680 1210045 NP_821635.1 CDS SAV_460 NC_003155.4 613088 613483 D hypothetical protein 613088..613483 Streptomyces avermitilis MA-4680 1212185 NP_821636.1 CDS SAV_461 NC_003155.4 613563 614081 R hypothetical protein complement(613563..614081) Streptomyces avermitilis MA-4680 1212186 NP_821637.1 CDS SAV_462 NC_003155.4 614386 614700 R hypothetical protein complement(614386..614700) Streptomyces avermitilis MA-4680 1212187 NP_821638.1 CDS SAV_463 NC_003155.4 614793 614951 R hypothetical protein complement(614793..614951) Streptomyces avermitilis MA-4680 1212188 NP_821639.1 CDS SAV_464 NC_003155.4 615205 615528 R hypothetical protein complement(615205..615528) Streptomyces avermitilis MA-4680 1212189 NP_821640.1 CDS SAV_465 NC_003155.4 615875 616378 D PF00190: Cupin doamin, 100% same as SAV878; hypothetical protein 615875..616378 Streptomyces avermitilis MA-4680 1212190 NP_821641.1 CDS SAV_466 NC_003155.4 618189 618728 D hypothetical protein 618189..618728 Streptomyces avermitilis MA-4680 1212191 NP_821642.1 CDS SAV_467 NC_003155.4 618731 619111 D hypothetical protein 618731..619111 Streptomyces avermitilis MA-4680 1212192 NP_821643.1 CDS SAV_468 NC_003155.4 619319 619990 D 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily; oxygenase 619319..619990 Streptomyces avermitilis MA-4680 1212193 NP_821644.1 CDS SAV_469 NC_003155.4 620530 621735 D PF03403: Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II; lipase 620530..621735 Streptomyces avermitilis MA-4680 1212194 NP_821645.1 CDS SAV_470 NC_003155.4 621832 622614 D PF01609: Transposase DDE domain; transposase 621832..622614 Streptomyces avermitilis MA-4680 1212195 NP_821646.1 CDS SAV_471 NC_003155.4 622993 623559 D PF01872: RibD C-terminal domain; hypothetical protein 622993..623559 Streptomyces avermitilis MA-4680 1212196 NP_821647.1 CDS SAV_472 NC_003155.4 624344 625432 R PF00165: Bacterial regulatory helix-turn-helix proteins, araC family; regulatory protein complement(624344..625432) Streptomyces avermitilis MA-4680 1212197 NP_821648.1 CDS SAV_473 NC_003155.4 625518 626249 R transposase complement(625518..626249) Streptomyces avermitilis MA-4680 1212198 NP_821649.1 CDS SAV_474 NC_003155.4 626420 627271 R methyltransferase complement(626420..627271) Streptomyces avermitilis MA-4680 1212199 NP_821650.1 CDS SAV_475 NC_003155.4 627377 627523 R hypothetical protein complement(627377..627523) Streptomyces avermitilis MA-4680 1212200 NP_821651.1 CDS SAV_476 NC_003155.4 627541 628107 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(627541..628107) Streptomyces avermitilis MA-4680 1212201 NP_821652.1 CDS SAV_477 NC_003155.4 628625 628882 D hypothetical protein 628625..628882 Streptomyces avermitilis MA-4680 1212202 NP_821653.1 CDS SAV_478 NC_003155.4 629473 629790 D hypothetical protein 629473..629790 Streptomyces avermitilis MA-4680 1212203 NP_821654.1 CDS SAV_479 NC_003155.4 629806 630354 R IS630 family (630954..629809) Translation will be controlled by framenshift with SAV480.; IS630 family transposase complement(629806..630354) Streptomyces avermitilis MA-4680 1212204 NP_821655.1 CDS SAV_480 NC_003155.4 630351 630686 R IS630 family (630954..629809) Target sequence (TA).; IS630 family transposase complement(630351..630686) Streptomyces avermitilis MA-4680 1212205 NP_821656.1 CDS SAV_482 NC_003155.4 630951 631274 R hypothetical protein complement(630951..631274) Streptomyces avermitilis MA-4680 1212206 NP_821657.1 CDS SAV_481 NC_003155.4 631222 631539 D hypothetical protein 631222..631539 Streptomyces avermitilis MA-4680 1212207 NP_821658.1 CDS SAV_483 NC_003155.4 631562 631783 R hypothetical protein complement(631562..631783) Streptomyces avermitilis MA-4680 1212208 NP_821659.1 CDS SAV_484 NC_003155.4 631817 632638 R ubiE/COQ5 methyltransferase family protein complement(631817..632638) Streptomyces avermitilis MA-4680 1212209 NP_821660.1 CDS SAV_485 NC_003155.4 632948 633259 D hypothetical protein 632948..633259 Streptomyces avermitilis MA-4680 1212210 NP_821661.1 CDS SAV_486 NC_003155.4 633243 633470 D hypothetical protein 633243..633470 Streptomyces avermitilis MA-4680 1212211 NP_821662.1 CDS SAV_487 NC_003155.4 633937 634218 R hypothetical protein complement(633937..634218) Streptomyces avermitilis MA-4680 1212212 NP_821663.1 CDS SAV_488 NC_003155.4 634378 635061 R TetR family transcriptional regulator complement(634378..635061) Streptomyces avermitilis MA-4680 1212213 NP_821664.1 CDS SAV_489 NC_003155.4 635181 635900 D hypothetical protein 635181..635900 Streptomyces avermitilis MA-4680 1212214 NP_821665.1 CDS SAV_490 NC_003155.4 636261 636563 R hypothetical protein complement(636261..636563) Streptomyces avermitilis MA-4680 1212215 NP_821666.1 CDS SAV_491 NC_003155.4 636931 637317 R PF01638: Transcriptional regulator; transcriptional regulator complement(636931..637317) Streptomyces avermitilis MA-4680 1212216 NP_821667.1 CDS echA1 NC_003155.4 637423 638256 D enoyl-CoA hydratase 637423..638256 Streptomyces avermitilis MA-4680 1210046 NP_821668.1 CDS SAV_493 NC_003155.4 639053 639388 R hypothetical protein complement(639053..639388) Streptomyces avermitilis MA-4680 1212217 NP_821669.1 CDS SAV_494 NC_003155.4 640006 640821 R hypothetical protein complement(640006..640821) Streptomyces avermitilis MA-4680 1212218 NP_821670.1 CDS SAV_495 NC_003155.4 641145 641333 D hypothetical protein 641145..641333 Streptomyces avermitilis MA-4680 1212219 NP_821671.1 CDS SAV_496 NC_003155.4 641343 641822 D hypothetical protein 641343..641822 Streptomyces avermitilis MA-4680 1212220 NP_821672.1 CDS int3 NC_003155.4 642389 642613 D probably pseudogene; integrase/recombinase 642389..642613 Streptomyces avermitilis MA-4680 1212221 NP_821673.1 CDS int4 NC_003155.4 642610 643092 D integrase/recombinase 642610..643092 Streptomyces avermitilis MA-4680 1212222 NP_821674.1 CDS SAV_499 NC_003155.4 643080 643727 R PF00320: GATA zinc finger; hypothetical protein complement(643080..643727) Streptomyces avermitilis MA-4680 1212223 NP_821675.1 CDS SAV_500 NC_003155.4 643739 644002 D hypothetical protein 643739..644002 Streptomyces avermitilis MA-4680 1212224 NP_821676.1 CDS SAV_501 NC_003155.4 644154 645011 R nuclease complement(644154..645011) Streptomyces avermitilis MA-4680 1212225 NP_821677.1 CDS SAV_502 NC_003155.4 645222 645671 R hypothetical protein complement(645222..645671) Streptomyces avermitilis MA-4680 1212226 NP_821678.1 CDS SAV_503 NC_003155.4 646464 646712 R hypothetical protein complement(646464..646712) Streptomyces avermitilis MA-4680 1212227 NP_821679.1 CDS infA2 NC_003155.4 646906 647130 R translation initiation factor IF-1 complement(646906..647130) Streptomyces avermitilis MA-4680 1210047 YP_187528.1 CDS SAV_7577 NC_003155.4 648107 648520 R IS5 family; hypothetical protein complement(648107..648520) Streptomyces avermitilis MA-4680 3238948 NP_821680.1 CDS SAV_505 NC_003155.4 648664 649314 R PF03992: Antibiotic biosynthesis monooxygenase; monooxygenase complement(648664..649314) Streptomyces avermitilis MA-4680 1212228 NP_821681.1 CDS SAV_506 NC_003155.4 650027 650887 D PF07690: Major Facilitator Superfamily; hypothetical protein 650027..650887 Streptomyces avermitilis MA-4680 1212229 NP_821682.1 CDS SAV_507 NC_003155.4 652300 653355 R cinnamoyl-CoA reductase complement(652300..653355) Streptomyces avermitilis MA-4680 1212230 NP_821683.1 CDS SAV_508 NC_003155.4 653742 654326 D TetR family transcriptional regulator 653742..654326 Streptomyces avermitilis MA-4680 1212231 NP_821684.1 CDS SAV_509 NC_003155.4 654353 654727 R transposase complement(654353..654727) Streptomyces avermitilis MA-4680 1212232 NP_821685.1 CDS SAV_510 NC_003155.4 654951 655112 D hypothetical protein 654951..655112 Streptomyces avermitilis MA-4680 1212233 NP_821686.1 CDS SAV_511 NC_003155.4 655559 656608 R PF01966: HD domain; hypothetical protein complement(655559..656608) Streptomyces avermitilis MA-4680 1212234 NP_821687.1 CDS SAV_512 NC_003155.4 656762 657562 R PF00561: alpha/beta hydrolase fold; hydrolase complement(656762..657562) Streptomyces avermitilis MA-4680 1212235 NP_821688.1 CDS SAV_513 NC_003155.4 657798 658799 D PF01965: DJ-1/PfpI family; AraC family transcription regulator 657798..658799 Streptomyces avermitilis MA-4680 1212236 NP_821689.1 CDS SAV_514 NC_003155.4 658738 659214 D hypothetical protein 658738..659214 Streptomyces avermitilis MA-4680 1212237 NP_821690.1 CDS SAV_515 NC_003155.4 659554 660030 R PF01799: [2Fe-2S] binding domain; oxidoreductase with iron-sulfur subunit complement(659554..660030) Streptomyces avermitilis MA-4680 1212238 NP_821691.1 CDS SAV_516 NC_003155.4 660050 662125 R PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; oxidoreductase complement(660050..662125) Streptomyces avermitilis MA-4680 1212239 NP_821692.1 CDS SAV_517 NC_003155.4 662516 663070 R PF01527: Transposase; hypothetical protein complement(662516..663070) Streptomyces avermitilis MA-4680 1212240 NP_821693.1 CDS SAV_518 NC_003155.4 663079 663246 R hypothetical protein complement(663079..663246) Streptomyces avermitilis MA-4680 1212241 NP_821694.1 CDS SAV_519 NC_003155.4 663296 664171 R PF00561: alpha/beta hydrolase fold; hydrolase complement(663296..664171) Streptomyces avermitilis MA-4680 1212242 NP_821695.1 CDS SAV_520 NC_003155.4 664226 664873 R PF01638: Transcriptional regulator; transcriptional regulator complement(664226..664873) Streptomyces avermitilis MA-4680 1212243 NP_821696.1 CDS SAV_521 NC_003155.4 665000 665731 D hypothetical protein 665000..665731 Streptomyces avermitilis MA-4680 1212244 NP_821697.1 CDS SAV_522 NC_003155.4 665728 665937 D hypothetical protein 665728..665937 Streptomyces avermitilis MA-4680 1212245 NP_821698.1 CDS SAV_523 NC_003155.4 666194 667279 R transposase complement(666194..667279) Streptomyces avermitilis MA-4680 1212246 NP_821699.1 CDS cdh NC_003155.4 668142 668879 D CDP-diacylglycerol phosphotidylhydrolase 668142..668879 Streptomyces avermitilis MA-4680 1212247 NP_821700.1 CDS SAV_525 NC_003155.4 669258 669710 D transposase 669258..669710 Streptomyces avermitilis MA-4680 1212248 NP_821701.1 CDS SAV_526 NC_003155.4 670688 671113 R hypothetical protein complement(670688..671113) Streptomyces avermitilis MA-4680 1212249 NP_821702.1 CDS sig4 NC_003155.4 671956 672573 D ECF subfamily RNA polymerase sigma factor 671956..672573 Streptomyces avermitilis MA-4680 1210048 NP_821703.1 CDS SAV_528 NC_003155.4 672570 673388 D integral membrane protein 672570..673388 Streptomyces avermitilis MA-4680 1212250 NP_821704.1 CDS SAV_529 NC_003155.4 673385 674218 D ABC transporter ATP-binding protein 673385..674218 Streptomyces avermitilis MA-4680 1212251 NP_821705.1 CDS SAV_530 NC_003155.4 674215 675609 D hypothetical protein 674215..675609 Streptomyces avermitilis MA-4680 1212252 NP_821706.1 CDS SAV_531 NC_003155.4 675606 676181 D hypothetical protein 675606..676181 Streptomyces avermitilis MA-4680 1212253 NP_821707.1 CDS SAV_532 NC_003155.4 676319 676693 D hypothetical protein 676319..676693 Streptomyces avermitilis MA-4680 1212254 NP_821708.1 CDS SAV_533 NC_003155.4 676902 677138 D hypothetical protein 676902..677138 Streptomyces avermitilis MA-4680 1212255 NP_821709.1 CDS SAV_534 NC_003155.4 677241 678026 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 677241..678026 Streptomyces avermitilis MA-4680 1212256 NP_821710.1 CDS SAV_535 NC_003155.4 678091 678423 D hypothetical protein 678091..678423 Streptomyces avermitilis MA-4680 1212257 NP_821711.1 CDS SAV_536 NC_003155.4 678456 678746 R hypothetical protein complement(678456..678746) Streptomyces avermitilis MA-4680 1212258 NP_821712.1 CDS SAV_537 NC_003155.4 679055 679966 D Sir2-family regulator protein 679055..679966 Streptomyces avermitilis MA-4680 1212259 NP_821713.1 CDS SAV_538 NC_003155.4 680351 680782 D hypothetical protein 680351..680782 Streptomyces avermitilis MA-4680 1212260 NP_821714.1 CDS SAV_539 NC_003155.4 681371 682687 R hypothetical protein complement(681371..682687) Streptomyces avermitilis MA-4680 1212261 NP_821715.1 CDS SAV_540 NC_003155.4 683712 684113 R MerR family transcriptional regulator complement(683712..684113) Streptomyces avermitilis MA-4680 1212262 NP_821716.1 CDS SAV_541 NC_003155.4 684229 684993 D PF00561: alpha/beta hydrolase fold; 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase 684229..684993 Streptomyces avermitilis MA-4680 1212263 NP_821717.1 CDS SAV_542 NC_003155.4 685826 686794 D hypothetical protein 685826..686794 Streptomyces avermitilis MA-4680 1212264 NP_821718.1 CDS folD2 NC_003155.4 687276 688139 R PF02882: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase complement(687276..688139) Streptomyces avermitilis MA-4680 1210049 NP_821719.1 CDS SAV_544 NC_003155.4 688569 689843 R PF00082: Subtilase family; serine protease complement(688569..689843) Streptomyces avermitilis MA-4680 1212265 NP_821720.1 CDS ribA NC_003155.4 690137 690814 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(690137..690814) Streptomyces avermitilis MA-4680 1210050 NP_821721.1 CDS SAV_546 NC_003155.4 690909 691955 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(690909..691955) Streptomyces avermitilis MA-4680 1212266 NP_821722.1 CDS SAV_547 NC_003155.4 692180 693268 R PF00515: TPR Domain; hypothetical protein complement(692180..693268) Streptomyces avermitilis MA-4680 1212267 NP_821723.1 CDS SAV_548 NC_003155.4 693265 694434 R hypothetical protein complement(693265..694434) Streptomyces avermitilis MA-4680 1212268 NP_821724.1 CDS SAV_549 NC_003155.4 694471 695799 R peroxidase complement(694471..695799) Streptomyces avermitilis MA-4680 1212269 NP_821725.1 CDS SAV_550 NC_003155.4 695916 696545 R hypothetical protein complement(695916..696545) Streptomyces avermitilis MA-4680 1212270 NP_821726.1 CDS SAV_551 NC_003155.4 696920 697507 R TetR family transcriptional regulator complement(696920..697507) Streptomyces avermitilis MA-4680 1212271 NP_821727.1 CDS SAV_552 NC_003155.4 697702 699213 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(697702..699213) Streptomyces avermitilis MA-4680 1212272 NP_821728.1 CDS SAV_553 NC_003155.4 700072 700701 R hypothetical protein complement(700072..700701) Streptomyces avermitilis MA-4680 1212273 NP_821729.1 CDS SAV_554 NC_003155.4 701238 702260 D LacI family transcriptional regulator 701238..702260 Streptomyces avermitilis MA-4680 1212274 NP_821730.1 CDS celA1 NC_003155.4 702503 703630 D endo-1,4-beta-glucanase 702503..703630 Streptomyces avermitilis MA-4680 1210051 NP_821731.1 CDS celS1 NC_003155.4 703943 704353 D cellulose binding protein 703943..704353 Streptomyces avermitilis MA-4680 1210052 NP_821732.1 CDS guxA1 NC_003155.4 704446 706671 D cellulose 1,4-beta-cellobiosidase 704446..706671 Streptomyces avermitilis MA-4680 1210053 NP_821733.1 CDS SAV_558 NC_003155.4 707738 708082 D hypothetical protein 707738..708082 Streptomyces avermitilis MA-4680 1212275 NP_821734.1 CDS SAV_559 NC_003155.4 708335 708796 D hypothetical protein 708335..708796 Streptomyces avermitilis MA-4680 1212276 NP_821735.1 CDS nicT1 NC_003155.4 709185 710330 D PF03824: High-affinity nickel-transport protein; high-affinity nickel-transport protein 709185..710330 Streptomyces avermitilis MA-4680 1212277 NP_821736.1 CDS SAV_561 NC_003155.4 710518 711135 R PF00881: Nitroreductase family; hypothetical protein complement(710518..711135) Streptomyces avermitilis MA-4680 1212278 NP_821737.1 CDS acsA3 NC_003155.4 711283 713301 R AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase complement(711283..713301) Streptomyces avermitilis MA-4680 1210054 NP_821738.1 CDS mhpA NC_003155.4 713315 714925 R catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase complement(713315..714925) Streptomyces avermitilis MA-4680 1210055 NP_821739.1 CDS SAV_564 NC_003155.4 714922 715860 R PF01557: Fumarylacetoacetate (FAA) hydrolase family; 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase complement(714922..715860) Streptomyces avermitilis MA-4680 1212279 NP_821740.1 CDS bphC NC_003155.4 715857 716894 R 2,3-dihydroxybiphenyl-1,2-dioxygenase complement(715857..716894) Streptomyces avermitilis MA-4680 1210056 NP_821741.1 CDS SAV_566 NC_003155.4 717140 717775 D TetR family transcriptional regulator 717140..717775 Streptomyces avermitilis MA-4680 1212280 NP_821742.1 CDS SAV_567 NC_003155.4 717968 719413 D PF01590: GAF domain; hypothetical protein 717968..719413 Streptomyces avermitilis MA-4680 1212281 NP_821743.1 CDS prpI1 NC_003155.4 719128 720147 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 719128..720147 Streptomyces avermitilis MA-4680 1212282 NP_821744.1 CDS SAV_569 NC_003155.4 720606 721364 D PF00561: alpha/beta hydrolase fold; hydrolase 720606..721364 Streptomyces avermitilis MA-4680 1212283 NP_821745.1 CDS ssgA3 NC_003155.4 721705 722091 D PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein 721705..722091 Streptomyces avermitilis MA-4680 1212284 NP_821746.1 CDS SAV_571 NC_003155.4 722855 723661 D PF03691: Uncharacterised protein family (UPF0167); hypothetical protein 722855..723661 Streptomyces avermitilis MA-4680 1212285 NP_821747.1 CDS SAV_572 NC_003155.4 723643 724497 R PF07287: Protein of unknown function (DUF1446); hypothetical protein complement(723643..724497) Streptomyces avermitilis MA-4680 1212286 NP_821748.1 CDS SAV_573 NC_003155.4 724687 725370 R hypothetical protein complement(724687..725370) Streptomyces avermitilis MA-4680 1212287 NP_821749.1 CDS SAV_574 NC_003155.4 725598 726644 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(725598..726644) Streptomyces avermitilis MA-4680 1212288 NP_821750.1 CDS cyp2 NC_003155.4 726776 729997 R CYP102D1, bifunctional P450:NADPH-P450 reductase; cytochrome P450 complement(726776..729997) Streptomyces avermitilis MA-4680 1210057 NP_821751.1 CDS SAV_576 NC_003155.4 730897 731553 D TetR family transcriptional regulator 730897..731553 Streptomyces avermitilis MA-4680 1212289 NP_821752.1 CDS SAV_577 NC_003155.4 732025 732822 R TetR family transcriptional regulator complement(732025..732822) Streptomyces avermitilis MA-4680 1212290 NP_821753.1 CDS SAV_578 NC_003155.4 733207 733389 R hypothetical protein complement(733207..733389) Streptomyces avermitilis MA-4680 1212291 NP_821754.1 CDS SAV_579 NC_003155.4 734105 734434 R hypothetical protein complement(734105..734434) Streptomyces avermitilis MA-4680 1212292 NP_821755.1 CDS ssgA4 NC_003155.4 734503 734922 R PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein complement(734503..734922) Streptomyces avermitilis MA-4680 1212293 NP_821756.1 CDS SAV_581 NC_003155.4 734950 735294 R hypothetical protein complement(734950..735294) Streptomyces avermitilis MA-4680 1212294 NP_821757.1 CDS fdxA NC_003155.4 735716 735925 D ferredoxin 735716..735925 Streptomyces avermitilis MA-4680 1210058 NP_821758.1 CDS fprA NC_003155.4 735915 737279 D ferredoxin reductase 735915..737279 Streptomyces avermitilis MA-4680 1210059 NP_821759.1 CDS cyp3 NC_003155.4 737312 738511 D CYP147B1, fdxA and fprA are located at upstream; cytochrome P450 737312..738511 Streptomyces avermitilis MA-4680 1210060 NP_821760.1 CDS SAV_585 NC_003155.4 738601 739236 R TetR family transcriptional regulator complement(738601..739236) Streptomyces avermitilis MA-4680 1212295 NP_821761.1 CDS prpL1 NC_003155.4 739502 741964 D PF00989: PAS domain, PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 739502..741964 Streptomyces avermitilis MA-4680 1212296 NP_821762.1 CDS prpJ1 NC_003155.4 742052 744481 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 742052..744481 Streptomyces avermitilis MA-4680 1212297 NP_821763.1 CDS SAV_588 NC_003155.4 744841 745287 R transcription regulator AsnC complement(744841..745287) Streptomyces avermitilis MA-4680 1212298 NP_821764.1 CDS SAV_589 NC_003155.4 745381 746199 D PF00296: Luciferase-like monooxygenase; F420-dependent dehydrogenase 745381..746199 Streptomyces avermitilis MA-4680 1212299 NP_821765.1 CDS cdd1 NC_003155.4 746196 746633 D PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region; cytidine/deoxycytidine deaminase 746196..746633 Streptomyces avermitilis MA-4680 1212300 NP_821766.1 CDS gvpK1 NC_003155.4 746752 747162 R gas vesicle synthesis protein complement(746752..747162) Streptomyces avermitilis MA-4680 1210061 NP_821767.1 CDS gvpS1 NC_003155.4 747159 747446 R gas vesicle synthesis protein complement(747159..747446) Streptomyces avermitilis MA-4680 1210062 NP_821768.1 CDS gvpL1 NC_003155.4 747446 748261 R gas vesicle synthesis protein complement(747446..748261) Streptomyces avermitilis MA-4680 1210063 NP_821769.1 CDS gvpJ1 NC_003155.4 748258 748707 R gas vesicle synthesis protein complement(748258..748707) Streptomyces avermitilis MA-4680 1210064 NP_821770.1 CDS SAV_595 NC_003155.4 748704 748928 R hypothetical protein complement(748704..748928) Streptomyces avermitilis MA-4680 1212301 NP_821771.1 CDS gvpG1 NC_003155.4 748925 749176 R gas vesicle synthesis protein complement(748925..749176) Streptomyces avermitilis MA-4680 1210065 NP_821772.1 CDS gvpF1 NC_003155.4 749194 749916 R gas vesicle synthesis protein complement(749194..749916) Streptomyces avermitilis MA-4680 1210066 NP_821773.1 CDS gvpA1 NC_003155.4 749920 750369 R similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins; gas vesicle synthesis-like protein complement(749920..750369) Streptomyces avermitilis MA-4680 1210067 NP_821774.1 CDS gvpO1 NC_003155.4 750480 750848 R gas vesicle synthesis protein complement(750480..750848) Streptomyces avermitilis MA-4680 1210068 NP_821775.1 CDS fecC NC_003155.4 751402 752148 R PF00005: ABC transporter; Fe+3/siderophore ABC transporter transport system ATP-binding protein complement(751402..752148) Streptomyces avermitilis MA-4680 1212302 NP_821776.1 CDS fecD NC_003155.4 752205 753176 R PF01032: FecCD transport family; Fe+3/siderophore ABC transporter permease complement(752205..753176) Streptomyces avermitilis MA-4680 1212303 NP_821777.1 CDS fecB NC_003155.4 753242 754285 R PF01497: Periplasmic binding protein; Fe+3/siderophore ABC transporter -binding protein complement(753242..754285) Streptomyces avermitilis MA-4680 1212304 NP_821778.1 CDS nrps6 NC_003155.4 754376 758698 R nrps6 gene cluster; non-ribosomal peptide synthetase complement(754376..758698) Streptomyces avermitilis MA-4680 1212305 NP_821779.1 CDS SAV_604 NC_003155.4 758706 758963 R nrps6 gene cluster, PF00550: Phosphopantetheine attachment site; hypothetical protein complement(758706..758963) Streptomyces avermitilis MA-4680 1212306 NP_821780.1 CDS fadD2 NC_003155.4 758996 760552 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(758996..760552) Streptomyces avermitilis MA-4680 1210069 NP_821781.1 CDS SAV_606 NC_003155.4 760605 761123 R nrps6 gene cluster; hypothetical protein complement(760605..761123) Streptomyces avermitilis MA-4680 1212307 NP_821782.1 CDS SAV_607 NC_003155.4 761120 762010 R nrps6 gene cluster, PF02668: Taurine catabolism dioxygenase TauD, TfdA family; taurine catabolism dioxygenase complement(761120..762010) Streptomyces avermitilis MA-4680 1212308 NP_821783.1 CDS fabC2 NC_003155.4 762046 762285 R nrps6 gene cluster, PF00550: Phosphopantetheine attachment site; ACP complement(762046..762285) Streptomyces avermitilis MA-4680 1210070 NP_821784.2 CDS fabH4 NC_003155.4 762282 763352 R FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase III complement(762282..763352) Streptomyces avermitilis MA-4680 1210071 NP_821785.1 CDS SAV_610 NC_003155.4 763424 764821 R PF07690: Major Facilitator Superfamily; MFS transporter protein complement(763424..764821) Streptomyces avermitilis MA-4680 1212309 NP_821786.1 CDS SAV_611 NC_003155.4 765101 765853 R PF05118: Aspartyl/Asparaginyl beta-hydroxylase; beta-hydroxylase complement(765101..765853) Streptomyces avermitilis MA-4680 1212310 NP_821787.1 CDS SAV_612 NC_003155.4 765882 766415 R hypothetical protein complement(765882..766415) Streptomyces avermitilis MA-4680 1212311 NP_821788.1 CDS SAV_613 NC_003155.4 767298 767819 D PF04314: Protein of unknown function (DUF461); hypothetical protein 767298..767819 Streptomyces avermitilis MA-4680 1212312 NP_821789.1 CDS sig5 NC_003155.4 767899 768552 R ECF subfamily RNA polymerase sigma factor complement(767899..768552) Streptomyces avermitilis MA-4680 1210072 NP_821790.1 CDS SAV_615 NC_003155.4 768752 769429 R hypothetical protein complement(768752..769429) Streptomyces avermitilis MA-4680 1212313 NP_821791.1 CDS SAV_616 NC_003155.4 769580 770101 R PF04314: Protein of unknown function (DUF461); hypothetical protein complement(769580..770101) Streptomyces avermitilis MA-4680 1212314 NP_821792.1 CDS ctpB NC_003155.4 770098 772353 R PF00122: E1-E2 ATPase; cation-transporting P-type ATPase complement(770098..772353) Streptomyces avermitilis MA-4680 1210073 NP_821793.1 CDS SAV_618 NC_003155.4 772353 772664 R hypothetical protein complement(772353..772664) Streptomyces avermitilis MA-4680 1212315 NP_821794.1 CDS SAV_619 NC_003155.4 773199 773498 R hypothetical protein complement(773199..773498) Streptomyces avermitilis MA-4680 1212316 NP_821795.1 CDS SAV_620 NC_003155.4 773556 774389 R PF00561: alpha/beta hydrolase fold; hydrolase complement(773556..774389) Streptomyces avermitilis MA-4680 1212317 NP_821796.1 CDS SAV_621 NC_003155.4 774469 774984 D MarR family transcriptional regulator 774469..774984 Streptomyces avermitilis MA-4680 1212318 NP_821797.1 CDS SAV_622 NC_003155.4 775498 775956 D hypothetical protein 775498..775956 Streptomyces avermitilis MA-4680 1212319 NP_821798.1 CDS SAV_623 NC_003155.4 776002 776298 D LuxR family transcriptional regulator 776002..776298 Streptomyces avermitilis MA-4680 1212320 NP_821799.1 CDS SAV_624 NC_003155.4 776473 777039 R hypothetical protein complement(776473..777039) Streptomyces avermitilis MA-4680 1212321 NP_821800.1 CDS SAV_625 NC_003155.4 777216 778127 D LysR family transcriptional regulator 777216..778127 Streptomyces avermitilis MA-4680 1212322 NP_821801.1 CDS SAV_626 NC_003155.4 778334 779140 D hypothetical protein 778334..779140 Streptomyces avermitilis MA-4680 1212323 NP_821802.1 CDS SAV_627 NC_003155.4 779554 781029 R PF03663: Glycosyl hydrolase family 76; glycosyl hydrolase complement(779554..781029) Streptomyces avermitilis MA-4680 1212324 NP_821803.1 CDS agaA1 NC_003155.4 781050 782660 R alpha-galactosidase complement(781050..782660) Streptomyces avermitilis MA-4680 1210074 NP_821804.1 CDS SAV_629 NC_003155.4 782844 783239 D hypothetical protein 782844..783239 Streptomyces avermitilis MA-4680 1212325 NP_821805.1 CDS SAV_630 NC_003155.4 783885 784940 R LacI family transcriptional regulator complement(783885..784940) Streptomyces avermitilis MA-4680 1212326 NP_821806.1 CDS SAV_632 NC_003155.4 785031 785402 R hypothetical protein complement(785031..785402) Streptomyces avermitilis MA-4680 1212327 NP_821807.1 CDS SAV_631 NC_003155.4 785356 785871 D PF00754: F5/8 type C domain; hypothetical protein 785356..785871 Streptomyces avermitilis MA-4680 1212328 NP_821808.1 CDS SAV_633 NC_003155.4 786451 786915 D hypothetical protein 786451..786915 Streptomyces avermitilis MA-4680 1212329 NP_821809.1 CDS SAV_634 NC_003155.4 788248 789312 D IS110 family; IS110 family transposase 788248..789312 Streptomyces avermitilis MA-4680 1212330 NP_821810.1 CDS echA2 NC_003155.4 789498 790355 R enoyl-CoA hydratase complement(789498..790355) Streptomyces avermitilis MA-4680 1210075 NP_821811.1 CDS SAV_636 NC_003155.4 790843 791451 R PF01965: DJ-1/PfpI family; AraC family transcription regulator complement(790843..791451) Streptomyces avermitilis MA-4680 1212331 NP_821812.1 CDS SAV_637 NC_003155.4 792236 792676 R hypothetical protein complement(792236..792676) Streptomyces avermitilis MA-4680 1212332 NP_821813.1 CDS SAV_638 NC_003155.4 793192 794145 D hypothetical protein 793192..794145 Streptomyces avermitilis MA-4680 1212333 NP_821814.1 CDS pkn1 NC_003155.4 794749 795285 R serine/threonine protein kinase complement(794749..795285) Streptomyces avermitilis MA-4680 1210076 NP_821815.1 CDS SAV_640 NC_003155.4 796901 797425 D hypothetical protein 796901..797425 Streptomyces avermitilis MA-4680 1212334 NP_821816.1 CDS SAV_641 NC_003155.4 797764 798072 D hypothetical protein 797764..798072 Streptomyces avermitilis MA-4680 1212335 NP_821817.1 CDS SAV_642 NC_003155.4 798051 801284 R PF05729: NACHT domain; hypothetical protein complement(798051..801284) Streptomyces avermitilis MA-4680 1212336 NP_821818.1 CDS SAV_643 NC_003155.4 801354 801581 R hypothetical protein complement(801354..801581) Streptomyces avermitilis MA-4680 1212337 NP_821819.1 CDS SAV_644 NC_003155.4 802775 803185 D hypothetical protein 802775..803185 Streptomyces avermitilis MA-4680 1212338 NP_821820.1 CDS SAV_645 NC_003155.4 803307 803486 R hypothetical protein complement(803307..803486) Streptomyces avermitilis MA-4680 1212339 NP_821821.1 CDS SAV_646 NC_003155.4 803533 804099 R frameshift; two-component system sensor kinase complement(803533..804099) Streptomyces avermitilis MA-4680 1212340 NP_821822.1 CDS SAV_647 NC_003155.4 804165 804863 R frameshift; sensor kinase complement(804165..804863) Streptomyces avermitilis MA-4680 1212341 NP_821823.1 CDS SAV_648 NC_003155.4 804917 805603 R two-component system response regulator complement(804917..805603) Streptomyces avermitilis MA-4680 1212342 NP_821824.1 CDS ard NC_003155.4 806100 806720 R similar to aminonucleoside antibiotic A201A phosphotransferase; phosphotransferase (aminonucleoside antibiotic resistance) complement(806100..806720) Streptomyces avermitilis MA-4680 1212343 NP_821825.1 CDS SAV_650 NC_003155.4 807493 808398 D methyltransferase 807493..808398 Streptomyces avermitilis MA-4680 1212344 NP_821826.1 CDS SAV_651 NC_003155.4 808509 808670 R hypothetical protein complement(808509..808670) Streptomyces avermitilis MA-4680 1212345 NP_821827.1 CDS SAV_652 NC_003155.4 809624 810859 R probable membrane efflux protein, PF07690: Major Facilitator Superfamily; fosmidmycin resistance protein complement(809624..810859) Streptomyces avermitilis MA-4680 1212346 NP_821828.1 CDS SAV_653 NC_003155.4 810866 811657 D PF00165: Bacterial regulatory helix-turn-helix proteins, araC family; AraC family transcription regulator 810866..811657 Streptomyces avermitilis MA-4680 1212347 NP_821829.1 CDS SAV_654 NC_003155.4 811793 812788 R PF00248: Aldo/keto reductase family; oxidoreductase complement(811793..812788) Streptomyces avermitilis MA-4680 1212348 NP_821830.1 CDS SAV_655 NC_003155.4 812915 813775 D DNA-binding protein 812915..813775 Streptomyces avermitilis MA-4680 1212349 NP_821831.1 CDS SAV_656 NC_003155.4 813831 814319 R hypothetical protein complement(813831..814319) Streptomyces avermitilis MA-4680 1212350 NP_821832.1 CDS SAV_657 NC_003155.4 814839 815231 R hypothetical protein complement(814839..815231) Streptomyces avermitilis MA-4680 1212351 NP_821833.1 CDS SAV_658 NC_003155.4 815233 816663 R hypothetical protein complement(815233..816663) Streptomyces avermitilis MA-4680 1212352 NP_821834.1 CDS SAV_659 NC_003155.4 817263 818171 R AraC family transcription regulator complement(817263..818171) Streptomyces avermitilis MA-4680 1212353 NP_821835.1 CDS blaB1 NC_003155.4 818311 818904 D PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase 818311..818904 Streptomyces avermitilis MA-4680 1210077 NP_821836.1 CDS SAV_661 NC_003155.4 818939 819619 R hypothetical protein complement(818939..819619) Streptomyces avermitilis MA-4680 1212354 NP_821837.1 CDS SAV_662 NC_003155.4 819960 820334 R hypothetical protein complement(819960..820334) Streptomyces avermitilis MA-4680 1212355 NP_821838.1 CDS sig6 NC_003155.4 820435 821349 D ECF subfamily RNA polymerase sigma factor 820435..821349 Streptomyces avermitilis MA-4680 1210078 NP_821839.1 CDS SAV_664 NC_003155.4 821389 822165 D methyltransferase 821389..822165 Streptomyces avermitilis MA-4680 1212356 NP_821840.1 CDS fabG1 NC_003155.4 822808 823653 R PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase complement(822808..823653) Streptomyces avermitilis MA-4680 1210079 NP_821841.1 CDS SAV_666 NC_003155.4 824426 824581 R hypothetical protein complement(824426..824581) Streptomyces avermitilis MA-4680 1212357 NP_821842.1 CDS lpdB1 NC_003155.4 824979 826418 R similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase; oxidoreductase complement(824979..826418) Streptomyces avermitilis MA-4680 1212358 NP_821843.1 CDS SAV_668 NC_003155.4 826839 827309 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; lyase complement(826839..827309) Streptomyces avermitilis MA-4680 1212359 NP_821844.1 CDS SAV_669 NC_003155.4 827554 828144 D TetR family transcriptional regulator 827554..828144 Streptomyces avermitilis MA-4680 1212360 NP_821845.1 CDS insA NC_003155.4 828242 829534 R PF01609: Transposase DDE domain; transposase complement(828242..829534) Streptomyces avermitilis MA-4680 1212361 NP_821846.1 CDS SAV_671 NC_003155.4 829572 830048 D PF02452: PemK-like protein; hypothetical protein 829572..830048 Streptomyces avermitilis MA-4680 1212362 NP_821847.1 CDS SAV_672 NC_003155.4 830486 830860 D hypothetical protein 830486..830860 Streptomyces avermitilis MA-4680 1212363 NP_821848.1 CDS SAV_673 NC_003155.4 830882 831715 D hypothetical protein 830882..831715 Streptomyces avermitilis MA-4680 1212364 NP_821849.1 CDS SAV_674 NC_003155.4 831803 832024 D hypothetical protein 831803..832024 Streptomyces avermitilis MA-4680 1212365 NP_821850.1 CDS SAV_675 NC_003155.4 832592 833383 R TetR family transcriptional regulator complement(832592..833383) Streptomyces avermitilis MA-4680 1212366 NP_821851.1 CDS SAV_676 NC_003155.4 833510 834505 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 833510..834505 Streptomyces avermitilis MA-4680 1212367 NP_821852.1 CDS SAV_677 NC_003155.4 834687 835604 R PF05200: Glutamyl-tRNAGlu reductase, NAD(P) binding domain; dehydrogenase complement(834687..835604) Streptomyces avermitilis MA-4680 1212368 NP_821853.1 CDS SAV_678 NC_003155.4 835665 836027 D PF01638: Transcriptional regulator; transcriptional regulator 835665..836027 Streptomyces avermitilis MA-4680 1212369 NP_821854.1 CDS SAV_679 NC_003155.4 836553 836768 D hypothetical protein 836553..836768 Streptomyces avermitilis MA-4680 1212370 NP_821855.1 CDS SAV_680 NC_003155.4 837091 837753 D hypothetical protein 837091..837753 Streptomyces avermitilis MA-4680 1212371 NP_821856.1 CDS SAV_681 NC_003155.4 837899 838645 D PF01636: Phosphotransferase enzyme family; phosphotransferase 837899..838645 Streptomyces avermitilis MA-4680 1212372 NP_821857.1 CDS SAV_682 NC_003155.4 838664 838882 R IS5 family; hypothetical protein complement(838664..838882) Streptomyces avermitilis MA-4680 1212373 NP_821858.1 CDS SAV_683 NC_003155.4 839061 839342 R transposase complement(839061..839342) Streptomyces avermitilis MA-4680 1212374 NP_821859.1 CDS SAV_684 NC_003155.4 839489 839665 R hypothetical protein complement(839489..839665) Streptomyces avermitilis MA-4680 1212375 NP_821860.1 CDS SAV_685 NC_003155.4 839801 840232 R hypothetical protein complement(839801..840232) Streptomyces avermitilis MA-4680 1212376 NP_821861.1 CDS SAV_686 NC_003155.4 840508 840777 D hypothetical protein 840508..840777 Streptomyces avermitilis MA-4680 1212377 NP_821862.1 CDS SAV_687 NC_003155.4 840896 841369 D PF03794: Domain of Unknown function; hypothetical protein 840896..841369 Streptomyces avermitilis MA-4680 1212378 NP_821863.1 CDS SAV_688 NC_003155.4 842362 842616 D hypothetical protein 842362..842616 Streptomyces avermitilis MA-4680 1212379 NP_821864.1 CDS SAV_689 NC_003155.4 842970 843443 R hypothetical protein complement(842970..843443) Streptomyces avermitilis MA-4680 1212380 NP_821865.1 CDS SAV_690 NC_003155.4 843495 843770 D transposase 843495..843770 Streptomyces avermitilis MA-4680 1212381 NP_821866.1 CDS SAV_691 NC_003155.4 843915 844562 R hsp18 transcriptional regulator complement(843915..844562) Streptomyces avermitilis MA-4680 1212382 NP_821867.1 CDS hsp18 NC_003155.4 844710 845141 D heat shock protein 844710..845141 Streptomyces avermitilis MA-4680 1210080 NP_821868.1 CDS SAV_693 NC_003155.4 846848 847663 R hypothetical protein complement(846848..847663) Streptomyces avermitilis MA-4680 1212383 NP_821869.1 CDS SAV_694 NC_003155.4 848379 849155 R ABC transporter permease complement(848379..849155) Streptomyces avermitilis MA-4680 1212384 NP_821870.1 CDS SAV_695 NC_003155.4 849152 850117 R ABC transporter ATP-binding protein complement(849152..850117) Streptomyces avermitilis MA-4680 1212385 NP_821871.1 CDS SAV_696 NC_003155.4 850165 850836 R hypothetical protein complement(850165..850836) Streptomyces avermitilis MA-4680 1212386 NP_821872.1 CDS SAV_697 NC_003155.4 851082 851816 D PF01047: MarR family; hypothetical protein 851082..851816 Streptomyces avermitilis MA-4680 1212387 NP_821873.1 CDS prpC1 NC_003155.4 851975 853549 R PF00989: PAS domain; magnesium or manganese-dependent protein phosphatase complement(851975..853549) Streptomyces avermitilis MA-4680 1212388 NP_821874.1 CDS SAV_699 NC_003155.4 853859 854782 D PF00106: short chain dehydrogenase; short chain dehydrogenase 853859..854782 Streptomyces avermitilis MA-4680 1212389 NP_821875.1 CDS sig7 NC_003155.4 854938 855585 D ECF subfamily RNA polymerase sigma factor 854938..855585 Streptomyces avermitilis MA-4680 1210081 NP_821876.1 CDS SAV_701 NC_003155.4 855582 856205 D hypothetical protein 855582..856205 Streptomyces avermitilis MA-4680 1212390 NP_821877.1 CDS SAV_702 NC_003155.4 856474 857739 D PF01757: Acyltransferase family; acyltransferase 856474..857739 Streptomyces avermitilis MA-4680 1212391 NP_821878.1 CDS SAV_703 NC_003155.4 858470 859033 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 858470..859033 Streptomyces avermitilis MA-4680 1212392 NP_821879.1 CDS SAV_704 NC_003155.4 859191 859688 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 859191..859688 Streptomyces avermitilis MA-4680 1212393 NP_821880.1 CDS SAV_705 NC_003155.4 860134 860766 D TetR family transcriptional regulator 860134..860766 Streptomyces avermitilis MA-4680 1212394 NP_821881.1 CDS SAV_706 NC_003155.4 861137 862141 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(861137..862141) Streptomyces avermitilis MA-4680 1212395 NP_821882.1 CDS SAV_707 NC_003155.4 862181 862846 R PF03807: NADP oxidoreductase coenzyme F420-dependent; hypothetical protein complement(862181..862846) Streptomyces avermitilis MA-4680 1212396 NP_821883.1 CDS SAV_708 NC_003155.4 862995 863978 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(862995..863978) Streptomyces avermitilis MA-4680 1212397 NP_821884.1 CDS SAV_709 NC_003155.4 864552 864953 R hypothetical protein complement(864552..864953) Streptomyces avermitilis MA-4680 1212398 NP_821885.1 CDS SAV_710 NC_003155.4 864970 865173 R hypothetical protein complement(864970..865173) Streptomyces avermitilis MA-4680 1212399 NP_821886.1 CDS SAV_711 NC_003155.4 865372 865893 R PF01638: Transcriptional regulator; transcriptional regulator complement(865372..865893) Streptomyces avermitilis MA-4680 1212400 NP_821887.1 CDS SAV_712 NC_003155.4 865902 866057 R hypothetical protein complement(865902..866057) Streptomyces avermitilis MA-4680 1212401 NP_821888.1 CDS SAV_713 NC_003155.4 866302 866511 R truncated; transposase complement(866302..866511) Streptomyces avermitilis MA-4680 1212402 NP_821889.1 CDS SAV_714 NC_003155.4 866655 867341 R phosphatase complement(866655..867341) Streptomyces avermitilis MA-4680 1212403 NP_821890.1 CDS SAV_715 NC_003155.4 867789 868694 R PF00058: Low-density lipoprotein receptor repeat class B; hypothetical protein complement(867789..868694) Streptomyces avermitilis MA-4680 1212404 NP_821891.1 CDS fadC6 NC_003155.4 868691 869677 R PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase complement(868691..869677) Streptomyces avermitilis MA-4680 1210082 NP_821892.1 CDS echA3 NC_003155.4 869743 870525 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(869743..870525) Streptomyces avermitilis MA-4680 1210083 NP_821893.1 CDS SAV_718 NC_003155.4 870522 871754 R fatty acid-CoA racemase complement(870522..871754) Streptomyces avermitilis MA-4680 1212405 NP_821894.1 CDS gcdH1 NC_003155.4 871760 873001 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; glutaryl-CoA dehydrogenase complement(871760..873001) Streptomyces avermitilis MA-4680 1210084 NP_821895.1 CDS SAV_720 NC_003155.4 873180 873584 D truncated; transposase 873180..873584 Streptomyces avermitilis MA-4680 1212406 NP_821896.1 CDS SAV_721 NC_003155.4 873611 873907 R hydrolase complement(873611..873907) Streptomyces avermitilis MA-4680 1212407 NP_821897.1 CDS SAV_722 NC_003155.4 875568 875810 D truncated; AraC family transcription regulator 875568..875810 Streptomyces avermitilis MA-4680 1212408 NP_821898.1 CDS SAV_723 NC_003155.4 875850 876020 D hypothetical protein 875850..876020 Streptomyces avermitilis MA-4680 1212409 NP_821899.1 CDS SAV_724 NC_003155.4 876545 877597 D PF00106: short chain dehydrogenase; dehydrogenase 876545..877597 Streptomyces avermitilis MA-4680 1212410 NP_821900.1 CDS SAV_725 NC_003155.4 877599 878420 R hypothetical protein complement(877599..878420) Streptomyces avermitilis MA-4680 1212411 NP_821901.1 CDS SAV_726 NC_003155.4 878482 879468 R oxidoreductase complement(878482..879468) Streptomyces avermitilis MA-4680 1212412 NP_821902.1 CDS SAV_727 NC_003155.4 880629 881234 R hypothetical protein complement(880629..881234) Streptomyces avermitilis MA-4680 1212413 NP_821903.1 CDS SAV_728 NC_003155.4 881179 881442 R hypothetical protein complement(881179..881442) Streptomyces avermitilis MA-4680 1212414 NP_821904.1 CDS SAV_729 NC_003155.4 881547 882500 R LysR family transcriptional regulator complement(881547..882500) Streptomyces avermitilis MA-4680 1212415 NP_821905.1 CDS SAV_730 NC_003155.4 882605 883498 D PF01073: 3-beta hydroxysteroid dehydrogenase/isomerase family; hypothetical protein 882605..883498 Streptomyces avermitilis MA-4680 1212416 NP_821906.1 CDS SAV_731 NC_003155.4 883572 883937 D hypothetical protein 883572..883937 Streptomyces avermitilis MA-4680 1212417 NP_821907.1 CDS SAV_732 NC_003155.4 884059 884292 D hypothetical protein 884059..884292 Streptomyces avermitilis MA-4680 1212418 NP_821908.1 CDS SAV_733 NC_003155.4 884559 885191 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(884559..885191) Streptomyces avermitilis MA-4680 1212419 NP_821909.1 CDS SAV_734 NC_003155.4 885591 887036 D PF03572: Peptidase family S41B; protease 885591..887036 Streptomyces avermitilis MA-4680 1212420 NP_821910.1 CDS SAV_735 NC_003155.4 887118 887300 D hypothetical protein 887118..887300 Streptomyces avermitilis MA-4680 1212421 NP_821911.1 CDS SAV_736 NC_003155.4 887475 887681 D PF00126: Bacterial regulatory helix-turn-helix protein, lysR family; transcriptional regulator 887475..887681 Streptomyces avermitilis MA-4680 1212422 NP_821912.1 CDS SAV_737 NC_003155.4 887698 888492 R PF00702: haloacid dehalogenase-like hydrolase; 2-haloalkanoic acid dehalogenase complement(887698..888492) Streptomyces avermitilis MA-4680 1212423 NP_821913.1 CDS SAV_738 NC_003155.4 888636 888812 R PF05532: CsbD-like; hypothetical protein complement(888636..888812) Streptomyces avermitilis MA-4680 1212424 NP_821914.1 CDS SAV_739 NC_003155.4 888992 889162 D hypothetical protein 888992..889162 Streptomyces avermitilis MA-4680 1212425 NP_821915.1 CDS SAV_740 NC_003155.4 889498 889851 D PF05239: PRC-barrel domain; hypothetical protein 889498..889851 Streptomyces avermitilis MA-4680 1212426 NP_821916.1 CDS sig8 NC_003155.4 890067 890906 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 890067..890906 Streptomyces avermitilis MA-4680 1210085 NP_821917.1 CDS SAV_742 NC_003155.4 891284 892279 D PF00165: Bacterial regulatory helix-turn-helix proteins, araC family; AraC family transcription regulator 891284..892279 Streptomyces avermitilis MA-4680 1212427 NP_821918.1 CDS SAV_743 NC_003155.4 892951 893352 D PF03995: Peptidase inhibitor family I36; peptidase inhibitor 892951..893352 Streptomyces avermitilis MA-4680 1212428 NP_821919.1 CDS SAV_744 NC_003155.4 893346 893903 R IS630 family transposase complement(893346..893903) Streptomyces avermitilis MA-4680 1212429 NP_821920.1 CDS SAV_745 NC_003155.4 893900 894439 R IS630 family transposase complement(893900..894439) Streptomyces avermitilis MA-4680 1212430 NP_821921.1 CDS SAV_746 NC_003155.4 894729 895703 D hypothetical protein 894729..895703 Streptomyces avermitilis MA-4680 1212431 NP_821922.1 CDS SAV_747 NC_003155.4 896150 897283 D hypothetical protein 896150..897283 Streptomyces avermitilis MA-4680 1212432 NP_821923.1 CDS SAV_748 NC_003155.4 897643 899004 D hypothetical protein 897643..899004 Streptomyces avermitilis MA-4680 1212433 NP_821924.1 CDS SAV_749 NC_003155.4 899196 899828 R methyltransferase complement(899196..899828) Streptomyces avermitilis MA-4680 1212434 NP_821925.1 CDS SAV_750 NC_003155.4 900012 900425 D TetR family transcriptional regulator 900012..900425 Streptomyces avermitilis MA-4680 1212435 NP_821926.1 CDS SAV_751 NC_003155.4 901504 902592 D ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase 901504..902592 Streptomyces avermitilis MA-4680 1212436 NP_821927.1 CDS SAV_752 NC_003155.4 903011 903400 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(903011..903400) Streptomyces avermitilis MA-4680 1212437 NP_821928.1 CDS SAV_753 NC_003155.4 903457 903648 R hypothetical protein complement(903457..903648) Streptomyces avermitilis MA-4680 1212438 NP_821929.1 CDS SAV_754 NC_003155.4 903755 904408 D TetR family transcriptional regulator 903755..904408 Streptomyces avermitilis MA-4680 1212439 NP_821930.1 CDS SAV_755 NC_003155.4 904587 905627 D PF00106: short chain dehydrogenase; dehydrogenase 904587..905627 Streptomyces avermitilis MA-4680 1212440 NP_821931.1 CDS SAV_756 NC_003155.4 906101 908071 R hypothetical protein complement(906101..908071) Streptomyces avermitilis MA-4680 1212441 NP_821932.1 CDS SAV_757 NC_003155.4 909086 910072 D PF03734: ErfK/YbiS/YcfS/YnhG; hypothetical protein 909086..910072 Streptomyces avermitilis MA-4680 1212442 NP_821933.1 CDS SAV_758 NC_003155.4 910889 911494 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(910889..911494) Streptomyces avermitilis MA-4680 1212443 NP_821934.1 CDS SAV_759 NC_003155.4 911580 912161 D hypothetical protein 911580..912161 Streptomyces avermitilis MA-4680 1212444 NP_821935.1 CDS SAV_760 NC_003155.4 912097 912768 R PF00394: Multicopper oxidase; multicopper oxidase complement(912097..912768) Streptomyces avermitilis MA-4680 1212445 NP_821936.1 CDS SAV_761 NC_003155.4 912621 912968 R hypothetical protein complement(912621..912968) Streptomyces avermitilis MA-4680 1212446 NP_821937.1 CDS SAV_762 NC_003155.4 913425 914252 D methyltransferase 913425..914252 Streptomyces avermitilis MA-4680 1212447 NP_821938.1 CDS SAV_763 NC_003155.4 914353 914658 R hypothetical protein complement(914353..914658) Streptomyces avermitilis MA-4680 1212448 NP_821939.1 CDS SAV_764 NC_003155.4 914734 915531 R hypothetical protein complement(914734..915531) Streptomyces avermitilis MA-4680 1212449 NP_821940.1 CDS SAV_765 NC_003155.4 915541 915750 R hypothetical protein complement(915541..915750) Streptomyces avermitilis MA-4680 1212450 NP_821941.1 CDS SAV_766 NC_003155.4 915952 916188 D hypothetical protein 915952..916188 Streptomyces avermitilis MA-4680 1212451 NP_821942.1 CDS prpJ2 NC_003155.4 916344 918416 R PF00989: PAS domain, PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(916344..918416) Streptomyces avermitilis MA-4680 1212452 NP_821943.1 CDS SAV_768 NC_003155.4 918676 919065 D hypothetical protein 918676..919065 Streptomyces avermitilis MA-4680 1212453 NP_821944.1 CDS SAV_769 NC_003155.4 919505 919888 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(919505..919888) Streptomyces avermitilis MA-4680 1212454 NP_821945.1 CDS SAV_770 NC_003155.4 920542 921387 R PF00106: short chain dehydrogenase; dehydrogenase complement(920542..921387) Streptomyces avermitilis MA-4680 1212455 NP_821946.1 CDS SAV_771 NC_003155.4 921494 922408 D LysR family transcriptional regulator 921494..922408 Streptomyces avermitilis MA-4680 1212456 NP_821947.1 CDS SAV_772 NC_003155.4 922521 922928 R GntR family transcriptional regulator complement(922521..922928) Streptomyces avermitilis MA-4680 1212457 NP_821948.1 CDS SAV_773 NC_003155.4 922853 923590 R hypothetical protein complement(922853..923590) Streptomyces avermitilis MA-4680 1212458 NP_821949.1 CDS SAV_774 NC_003155.4 923778 925370 R PF01360: Monooxygenase; monooxygenase complement(923778..925370) Streptomyces avermitilis MA-4680 1212459 NP_821950.1 CDS SAV_775 NC_003155.4 925541 926167 D similar to actII-1; TetR family transcriptional regulator 925541..926167 Streptomyces avermitilis MA-4680 1212460 NP_821951.1 CDS SAV_776 NC_003155.4 926268 926516 R hypothetical protein complement(926268..926516) Streptomyces avermitilis MA-4680 1212461 NP_821952.1 CDS SAV_777 NC_003155.4 926586 927077 R hypothetical protein complement(926586..927077) Streptomyces avermitilis MA-4680 1212462 NP_821953.1 CDS SAV_778 NC_003155.4 927524 928555 D PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein 927524..928555 Streptomyces avermitilis MA-4680 1212463 NP_821954.1 CDS SAV_779 NC_003155.4 928799 928972 D transposase 928799..928972 Streptomyces avermitilis MA-4680 1212464 NP_821955.1 CDS SAV_780 NC_003155.4 929152 930075 R PF00296: Luciferase-like monooxygenase; monooxygenase complement(929152..930075) Streptomyces avermitilis MA-4680 1212465 NP_821956.1 CDS SAV_781 NC_003155.4 930473 930895 D hypothetical protein 930473..930895 Streptomyces avermitilis MA-4680 1212466 NP_821957.1 CDS SAV_782 NC_003155.4 930904 931179 R hypothetical protein complement(930904..931179) Streptomyces avermitilis MA-4680 1212467 NP_821958.1 CDS SAV_783 NC_003155.4 931759 932133 D hypothetical protein 931759..932133 Streptomyces avermitilis MA-4680 1212468 NP_821959.1 CDS SAV_784 NC_003155.4 932225 932773 D hypothetical protein 932225..932773 Streptomyces avermitilis MA-4680 1212469 NP_821960.1 CDS SAV_785 NC_003155.4 934229 934714 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(934229..934714) Streptomyces avermitilis MA-4680 1212470 NP_821961.1 CDS prpJ3 NC_003155.4 935953 938727 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; membrane protein; magnesium or manganese-dependent protein phosphatase complement(935953..938727) Streptomyces avermitilis MA-4680 1212471 NP_821962.1 CDS SAV_787 NC_003155.4 939117 939773 R weak similarity to chloramphenicol phosphotransferase; hypothetical protein complement(939117..939773) Streptomyces avermitilis MA-4680 1212472 NP_821963.1 CDS SAV_788 NC_003155.4 940165 940638 R PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein complement(940165..940638) Streptomyces avermitilis MA-4680 1212473 NP_821964.1 CDS SAV_789 NC_003155.4 940910 942349 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(940910..942349) Streptomyces avermitilis MA-4680 1212474 NP_821965.1 CDS SAV_790 NC_003155.4 942366 942767 R hypothetical protein complement(942366..942767) Streptomyces avermitilis MA-4680 1212475 NP_821966.1 CDS SAV_791 NC_003155.4 942846 944381 R PF02133: Permease for cytosine/purines, uracil, thiamine, allantoin; transmembrane transport protein complement(942846..944381) Streptomyces avermitilis MA-4680 1212476 NP_821967.1 CDS SAV_792 NC_003155.4 944545 945936 D transcriptional regulator 944545..945936 Streptomyces avermitilis MA-4680 1212477 NP_821968.1 CDS SAV_793 NC_003155.4 946221 946775 D PF07681: DoxX; hypothetical protein 946221..946775 Streptomyces avermitilis MA-4680 1212478 NP_821969.1 CDS SAV_794 NC_003155.4 947036 948439 D amino acid permease; ABC transporter permease 947036..948439 Streptomyces avermitilis MA-4680 1212479 NP_821970.1 CDS SAV_795 NC_003155.4 948548 949270 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(948548..949270) Streptomyces avermitilis MA-4680 1212480 NP_821971.1 CDS SAV_796 NC_003155.4 949418 950035 R hypothetical protein complement(949418..950035) Streptomyces avermitilis MA-4680 1212481 NP_821972.1 CDS SAV_797 NC_003155.4 950601 950984 R hypothetical protein complement(950601..950984) Streptomyces avermitilis MA-4680 1212482 NP_821973.1 CDS SAV_798 NC_003155.4 950995 951585 R hypothetical protein complement(950995..951585) Streptomyces avermitilis MA-4680 1212483 NP_821974.1 CDS SAV_799 NC_003155.4 951567 951881 R hypothetical protein complement(951567..951881) Streptomyces avermitilis MA-4680 1212484 NP_821975.1 CDS SAV_800 NC_003155.4 951882 952160 D hypothetical protein 951882..952160 Streptomyces avermitilis MA-4680 1212485 NP_821976.1 CDS argG1 NC_003155.4 952657 954111 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 952657..954111 Streptomyces avermitilis MA-4680 1210086 NP_821977.1 CDS SAV_802 NC_003155.4 954464 955318 D hypothetical protein 954464..955318 Streptomyces avermitilis MA-4680 1212486 NP_821978.1 CDS pgmA NC_003155.4 955607 957277 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(955607..957277) Streptomyces avermitilis MA-4680 1210087 NP_821979.1 CDS SAV_804 NC_003155.4 957808 958059 R hypothetical protein complement(957808..958059) Streptomyces avermitilis MA-4680 1212487 NP_821980.1 CDS SAV_805 NC_003155.4 958134 958262 R hypothetical protein complement(958134..958262) Streptomyces avermitilis MA-4680 1212488 NP_821981.1 CDS SAV_806 NC_003155.4 958610 960352 D PF00515: TRP domain; hypothetical protein 958610..960352 Streptomyces avermitilis MA-4680 1212489 NP_821982.1 CDS SAV_807 NC_003155.4 960571 960810 D hypothetical protein 960571..960810 Streptomyces avermitilis MA-4680 1212490 NP_821983.1 CDS prpC2 NC_003155.4 961036 962355 R PF00989: PAS domain; magnesium or manganese-dependent protein phosphatase complement(961036..962355) Streptomyces avermitilis MA-4680 1212491 NP_821984.1 CDS sig9 NC_003155.4 962573 963100 R ECF subfamily RNA polymerase sigma factor complement(962573..963100) Streptomyces avermitilis MA-4680 1210088 NP_821985.1 CDS SAV_810 NC_003155.4 963156 964286 R PF00070: Pyridine nucleotide-disulphide oxidoreductase; dehydrogenase complement(963156..964286) Streptomyces avermitilis MA-4680 1212492 NP_821986.1 CDS SAV_811 NC_003155.4 964283 964678 R hypothetical protein complement(964283..964678) Streptomyces avermitilis MA-4680 1212493 NP_821987.1 CDS SAV_812 NC_003155.4 964891 965100 R small hydrophilic protein complement(964891..965100) Streptomyces avermitilis MA-4680 1212494 NP_821988.1 CDS SAV_813 NC_003155.4 965305 965661 R PF05239: PRC-barrel domain; hypothetical protein complement(965305..965661) Streptomyces avermitilis MA-4680 1212495 NP_821989.1 CDS SAV_814 NC_003155.4 966143 966421 R hypothetical protein complement(966143..966421) Streptomyces avermitilis MA-4680 1212496 NP_821990.1 CDS SAV_815 NC_003155.4 967134 967313 D hypothetical protein 967134..967313 Streptomyces avermitilis MA-4680 1212497 NP_821991.1 CDS SAV_816 NC_003155.4 967424 967597 D PF05532: CsbD-like; hypothetical protein 967424..967597 Streptomyces avermitilis MA-4680 1212498 NP_821992.1 CDS SAV_817 NC_003155.4 968219 968503 R hypothetical protein complement(968219..968503) Streptomyces avermitilis MA-4680 1212499 NP_821993.1 CDS SAV_818 NC_003155.4 968939 970015 D hypothetical protein 968939..970015 Streptomyces avermitilis MA-4680 1212500 NP_821994.1 CDS SAV_819 NC_003155.4 970221 971444 D lipase 970221..971444 Streptomyces avermitilis MA-4680 1212501 NP_821995.1 CDS SAV_820 NC_003155.4 971806 972096 R hypothetical protein complement(971806..972096) Streptomyces avermitilis MA-4680 1212502 NP_821996.1 CDS SAV_821 NC_003155.4 972201 972629 R IS200/IS605 family; IS200-like transposase complement(972201..972629) Streptomyces avermitilis MA-4680 1212503 NP_821997.1 CDS SAV_822 NC_003155.4 972680 973894 D IS200/IS605 family; IS200-like transposase 972680..973894 Streptomyces avermitilis MA-4680 1212504 NP_821998.1 CDS SAV_823 NC_003155.4 974221 974766 R hypothetical protein complement(974221..974766) Streptomyces avermitilis MA-4680 1212505 NP_821999.1 CDS SAV_824 NC_003155.4 975546 975818 D hypothetical protein 975546..975818 Streptomyces avermitilis MA-4680 1212506 NP_822000.1 CDS aph1 NC_003155.4 976138 977037 R aminoglycoside phosphotransferase complement(976138..977037) Streptomyces avermitilis MA-4680 1210089 NP_822001.1 CDS cspD1 NC_003155.4 977461 977664 R cold shock protein complement(977461..977664) Streptomyces avermitilis MA-4680 1210090 NP_822002.1 CDS fabH6 NC_003155.4 978292 979311 D 3-oxoacyl-ACP synthase III 978292..979311 Streptomyces avermitilis MA-4680 1210091 NP_822003.1 CDS SAV_828 NC_003155.4 979582 982674 R PF05592: Bacterial alpha-L-rhamnosidase; rhamnosidase complement(979582..982674) Streptomyces avermitilis MA-4680 1212507 NP_822004.1 CDS SAV_829 NC_003155.4 983146 983523 R hypothetical protein complement(983146..983523) Streptomyces avermitilis MA-4680 1212508 NP_822005.1 CDS SAV_830 NC_003155.4 983523 983747 R hypothetical protein complement(983523..983747) Streptomyces avermitilis MA-4680 1212509 NP_822006.1 CDS SAV_831 NC_003155.4 983914 984960 R LacI family transcriptional regulator complement(983914..984960) Streptomyces avermitilis MA-4680 1212510 NP_822007.1 CDS SAV_832 NC_003155.4 984957 985991 R GFO/IDH/MOCA-family protein complement(984957..985991) Streptomyces avermitilis MA-4680 1212511 NP_822008.1 CDS SAV_833 NC_003155.4 985988 986839 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(985988..986839) Streptomyces avermitilis MA-4680 1212512 NP_822009.1 CDS SAV_834 NC_003155.4 986811 988160 R sensory transduction pleiotropic regulatory protein complement(986811..988160) Streptomyces avermitilis MA-4680 1212513 NP_822010.1 CDS SAV_835 NC_003155.4 988169 989314 R glycosyltransferase complement(988169..989314) Streptomyces avermitilis MA-4680 1212514 NP_822011.1 CDS matE NC_003155.4 989357 990832 R PF01554: MatE; efflux family protein complement(989357..990832) Streptomyces avermitilis MA-4680 1212515 NP_822012.1 CDS SAV_837 NC_003155.4 991134 991487 R NADH:FMN oxidoreductase complement(991134..991487) Streptomyces avermitilis MA-4680 1212516 NP_822013.1 CDS cyp4 NC_003155.4 991484 992719 R CYP178A1, nrps7 gene cluster; cytochrome P450 complement(991484..992719) Streptomyces avermitilis MA-4680 1210092 NP_822014.1 CDS nrps7-1 NC_003155.4 992728 994536 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(992728..994536) Streptomyces avermitilis MA-4680 1212517 NP_822015.1 CDS SAV_840 NC_003155.4 994545 995348 R nrps7 gene cluster; thioesterase complement(994545..995348) Streptomyces avermitilis MA-4680 1212518 NP_822016.1 CDS SAV_841 NC_003155.4 995480 996217 R nrps7 gene cluster; ThiG-like protein complement(995480..996217) Streptomyces avermitilis MA-4680 1212519 NP_822017.1 CDS SAV_842 NC_003155.4 996214 997125 R nrps7 gene cluster; branched-chain amino acid aminotransferase complement(996214..997125) Streptomyces avermitilis MA-4680 1212520 NP_822018.1 CDS SAV_843 NC_003155.4 997152 997847 R nrps7 gene cluster; thioesterase complement(997152..997847) Streptomyces avermitilis MA-4680 1212521 NP_822019.1 CDS nrps7-2 NC_003155.4 997877 999166 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(997877..999166) Streptomyces avermitilis MA-4680 1212522 NP_822020.1 CDS SAV_845 NC_003155.4 999163 1002321 R nrps7 gene cluster; modular polyketide synthase complement(999163..1002321) Streptomyces avermitilis MA-4680 1212523 NP_822021.1 CDS nrps7-3 NC_003155.4 1002287 1004011 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1002287..1004011) Streptomyces avermitilis MA-4680 1212524 NP_822022.1 CDS nrps7-4 NC_003155.4 1004016 1007462 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1004016..1007462) Streptomyces avermitilis MA-4680 1212525 NP_822023.1 CDS nrps7-5 NC_003155.4 1007459 1009384 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1007459..1009384) Streptomyces avermitilis MA-4680 1212526 NP_822024.1 CDS SAV_849 NC_003155.4 1009432 1011063 R nrps7 gene cluster; methyltransferase complement(1009432..1011063) Streptomyces avermitilis MA-4680 1212527 NP_822025.1 CDS SAV_850 NC_003155.4 1012883 1013704 D nrps7 gene cluster; hypothetical protein 1012883..1013704 Streptomyces avermitilis MA-4680 1212528 NP_822026.1 CDS SAV_851 NC_003155.4 1013750 1013968 R nrps7 gene cluster; MbtH-like protein complement(1013750..1013968) Streptomyces avermitilis MA-4680 1212529 NP_822027.1 CDS nrps7-6 NC_003155.4 1014084 1015736 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1014084..1015736) Streptomyces avermitilis MA-4680 1212530 NP_822028.1 CDS nrps7-7 NC_003155.4 1015739 1017331 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1015739..1017331) Streptomyces avermitilis MA-4680 1212531 NP_822029.1 CDS SAV_854 NC_003155.4 1017328 1019550 R nrps7 gene cluster; amidase complement(1017328..1019550) Streptomyces avermitilis MA-4680 1212532 NP_822030.1 CDS nrps7-8 NC_003155.4 1019547 1021202 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1019547..1021202) Streptomyces avermitilis MA-4680 1212533 NP_822031.1 CDS SAV_856 NC_003155.4 1021234 1022031 R nrps7 gene cluster; thioesterase complement(1021234..1022031) Streptomyces avermitilis MA-4680 1212534 NP_822032.1 CDS nrps7-9 NC_003155.4 1023063 1024484 D nrps7 gene cluster; non-ribosomal peptide synthetase 1023063..1024484 Streptomyces avermitilis MA-4680 1212535 NP_822033.1 CDS SAV_858 NC_003155.4 1024676 1024900 D nrps7 gene cluster; hypothetical protein 1024676..1024900 Streptomyces avermitilis MA-4680 1212536 NP_822034.1 CDS nrps7-10 NC_003155.4 1025128 1026513 D nrps7 gene cluster; non-ribosomal peptide synthetase 1025128..1026513 Streptomyces avermitilis MA-4680 1212537 NP_822035.1 CDS nrps7-11 NC_003155.4 1026551 1028176 D nrps7 gene cluster; non-ribosomal peptide synthetase 1026551..1028176 Streptomyces avermitilis MA-4680 1212538 NP_822036.1 CDS SAV_861 NC_003155.4 1028236 1029129 D nrps7 gene cluster; reductase 1028236..1029129 Streptomyces avermitilis MA-4680 1212539 NP_822037.1 CDS SAV_862 NC_003155.4 1029133 1031103 R nrps7 gene cluster; hypothetical protein complement(1029133..1031103) Streptomyces avermitilis MA-4680 1212540 NP_822038.1 CDS SAV_863 NC_003155.4 1031106 1032413 R Catalyzes the formation of malnoyl-CoA, which in turn controls the rate of fatty acid metabolism; hypothetical protein complement(1031106..1032413) Streptomyces avermitilis MA-4680 1212541 NP_822039.1 CDS SAV_864 NC_003155.4 1032421 1032669 R nrps7 gene cluster; peptide carrier protein complement(1032421..1032669) Streptomyces avermitilis MA-4680 1212542 NP_822040.1 CDS nrps7-12 NC_003155.4 1032666 1035416 R nrps7 gene cluster; non-ribosomal peptide synthetase complement(1032666..1035416) Streptomyces avermitilis MA-4680 1212543 NP_822041.1 CDS SAV_866 NC_003155.4 1035525 1035992 R nrps7 gene cluster; hypothetical protein complement(1035525..1035992) Streptomyces avermitilis MA-4680 1212544 NP_822042.1 CDS SAV_867 NC_003155.4 1036695 1038659 D nrps7 gene cluster; ABC transporter ATP-binding protein 1036695..1038659 Streptomyces avermitilis MA-4680 1212545 NP_822043.1 CDS SAV_868 NC_003155.4 1038659 1040461 D nrps7 gene cluster; ABC transporter ATP-binding protein 1038659..1040461 Streptomyces avermitilis MA-4680 1212546 NP_822044.1 CDS nrps7-13 NC_003155.4 1040665 1042269 D nrps7 gene cluster; non-ribosomal peptide synthetase 1040665..1042269 Streptomyces avermitilis MA-4680 1212547 NP_822045.1 CDS SAV_870 NC_003155.4 1042274 1042495 D hypothetical protein 1042274..1042495 Streptomyces avermitilis MA-4680 1212548 NP_822046.1 CDS SAV_871 NC_003155.4 1042499 1043434 D PF05721: Phytanoyl-CoA dioxygenase (PhyH); dioxygenase 1042499..1043434 Streptomyces avermitilis MA-4680 1212549 NP_822047.1 CDS SAV_872 NC_003155.4 1043718 1044683 D PF00248: Aldo/keto reductase family; oxidoreductase 1043718..1044683 Streptomyces avermitilis MA-4680 1212550 NP_822048.1 CDS SAV_873 NC_003155.4 1044960 1045295 R PF03621: MbtH-like protein; hypothetical protein complement(1044960..1045295) Streptomyces avermitilis MA-4680 1212551 NP_822049.1 CDS SAV_874 NC_003155.4 1045629 1047416 D PF00497: Bacterial extracellular solute-binding proteins, family 3; solute-binding dependent transport lipoprotein 1045629..1047416 Streptomyces avermitilis MA-4680 1212552 NP_822050.1 CDS pip NC_003155.4 1047772 1048737 R PF00561: alpha/beta hydrolase fold; proline iminopeptidase complement(1047772..1048737) Streptomyces avermitilis MA-4680 1212553 NP_822051.1 CDS SAV_876 NC_003155.4 1049165 1049596 D hypothetical protein 1049165..1049596 Streptomyces avermitilis MA-4680 1212554 NP_822052.1 CDS cpt NC_003155.4 1050455 1050985 D similar to Cpt(Q56148) chloramphenicol-producing Streptomyces venezuelae. Streptomyces coelicolor A3(2) has different resistance mechanism (probably efflux, CmlR); chloramphenicol 3-O phosphotransferase 1050455..1050985 Streptomyces avermitilis MA-4680 1210093 NP_822053.1 CDS SAV_878 NC_003155.4 1051615 1052112 D PF00190: Cupin doamin, 100% same as SAV465; hypothetical protein 1051615..1052112 Streptomyces avermitilis MA-4680 1212555 NP_822054.1 CDS ku2 NC_003155.4 1052915 1053874 R probably involving non-homologous end-joining; Ku70/Ku80 protein complement(1052915..1053874) Streptomyces avermitilis MA-4680 1212556 NP_822055.1 CDS SAV_880 NC_003155.4 1054267 1054536 R TetR family transcriptional regulator complement(1054267..1054536) Streptomyces avermitilis MA-4680 1212557 NP_822056.1 CDS SAV_881 NC_003155.4 1054718 1055842 D PF01360: Monooxygenase; monooxygenase 1054718..1055842 Streptomyces avermitilis MA-4680 1212558 NP_822057.1 CDS SAV_882 NC_003155.4 1056028 1056786 R TetR family transcriptional regulator complement(1056028..1056786) Streptomyces avermitilis MA-4680 1212559 NP_822058.1 CDS SAV_883 NC_003155.4 1056846 1057706 D PF01113: Dihydrodipicolinate reductase, N-terminus; hypothetical protein 1056846..1057706 Streptomyces avermitilis MA-4680 1212560 NP_822059.1 CDS SAV_884 NC_003155.4 1057857 1058840 D PF00665: Integrase core domain; transposase 1057857..1058840 Streptomyces avermitilis MA-4680 1212561 NP_822060.1 CDS SAV_885 NC_003155.4 1059494 1059823 D PF03992: Antibiotic biosynthesis monooxygenase; hypothetical protein 1059494..1059823 Streptomyces avermitilis MA-4680 1212562 NP_822061.1 CDS SAV_886 NC_003155.4 1060061 1060657 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(1060061..1060657) Streptomyces avermitilis MA-4680 1212563 NP_822062.1 CDS SAV_887 NC_003155.4 1061121 1065185 D PF00754: F5/8 type C domain; glycosyl hydrolase 1061121..1065185 Streptomyces avermitilis MA-4680 1212564 NP_822063.1 CDS SAV_888 NC_003155.4 1065315 1066835 R PF00561: alpha/beta hydrolase fold; hydrolase complement(1065315..1066835) Streptomyces avermitilis MA-4680 1212565 NP_822064.1 CDS SAV_889 NC_003155.4 1066921 1067280 R hypothetical protein complement(1066921..1067280) Streptomyces avermitilis MA-4680 1212566 NP_822065.1 CDS SAV_890 NC_003155.4 1067692 1069515 D hypothetical protein 1067692..1069515 Streptomyces avermitilis MA-4680 1212567 NP_822066.1 CDS SAV_891 NC_003155.4 1069805 1070419 R quaternary amine transporter complement(1069805..1070419) Streptomyces avermitilis MA-4680 1212568 NP_822067.1 CDS SAV_892 NC_003155.4 1070683 1071018 R hypothetical protein complement(1070683..1071018) Streptomyces avermitilis MA-4680 1212569 NP_822068.1 CDS cspD2 NC_003155.4 1071654 1071857 R cold shock protein complement(1071654..1071857) Streptomyces avermitilis MA-4680 1210094 NP_822069.1 CDS SAV_894 NC_003155.4 1072353 1072856 R hypothetical protein complement(1072353..1072856) Streptomyces avermitilis MA-4680 1212570 NP_822070.1 CDS SAV_895 NC_003155.4 1073232 1073465 R hypothetical protein complement(1073232..1073465) Streptomyces avermitilis MA-4680 1212571 NP_822071.1 CDS terD1 NC_003155.4 1074296 1074871 D PF02342: Bacterial stress protein; tellurium resistance protein 1074296..1074871 Streptomyces avermitilis MA-4680 1212572 NP_822072.1 CDS SAV_897 NC_003155.4 1075047 1075406 R alpha-amylase inhibitor complement(1075047..1075406) Streptomyces avermitilis MA-4680 1212573 NP_822073.1 CDS sig10 NC_003155.4 1076865 1077479 R ECF subfamily RNA polymerase sigma factor complement(1076865..1077479) Streptomyces avermitilis MA-4680 1210095 NP_822074.1 CDS SAV_899 NC_003155.4 1077654 1078340 R hypothetical protein complement(1077654..1078340) Streptomyces avermitilis MA-4680 1212574 NP_822075.1 CDS SAV_900 NC_003155.4 1078669 1079067 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(1078669..1079067) Streptomyces avermitilis MA-4680 1212575 NP_822076.1 CDS SAV_901 NC_003155.4 1079174 1080226 D transcriptional regulator 1079174..1080226 Streptomyces avermitilis MA-4680 1212576 NP_822077.1 CDS SAV_902 NC_003155.4 1080407 1080958 D hypothetical protein 1080407..1080958 Streptomyces avermitilis MA-4680 1212577 NP_822078.1 CDS SAV_903 NC_003155.4 1081464 1082558 D hypothetical protein 1081464..1082558 Streptomyces avermitilis MA-4680 1212578 NP_822079.1 CDS SAV_904 NC_003155.4 1082866 1083876 D PF00248: Aldo/keto reductase family; oxidoreductase 1082866..1083876 Streptomyces avermitilis MA-4680 1212579 NP_822080.1 CDS SAV_905 NC_003155.4 1084639 1084959 R hypothetical protein complement(1084639..1084959) Streptomyces avermitilis MA-4680 1212580 NP_822081.1 CDS SAV_906 NC_003155.4 1085023 1086564 R PF00561: alpha/beta hydrolase fold; protease complement(1085023..1086564) Streptomyces avermitilis MA-4680 1212581 NP_822082.1 CDS SAV_907 NC_003155.4 1086726 1087349 R hypothetical protein complement(1086726..1087349) Streptomyces avermitilis MA-4680 1212582 NP_822083.1 CDS SAV_908 NC_003155.4 1087677 1088615 D PF01073: 3-beta hydroxysteroid dehydrogenase/isomerase family; dehydrogenase 1087677..1088615 Streptomyces avermitilis MA-4680 1212583 NP_822084.1 CDS sig11 NC_003155.4 1088612 1089535 D ECF subfamily RNA polymerase sigma factor 1088612..1089535 Streptomyces avermitilis MA-4680 1210096 NP_822085.1 CDS SAV_910 NC_003155.4 1089696 1090277 D PF03358: NADPH-dependent FMN reductase; reductase 1089696..1090277 Streptomyces avermitilis MA-4680 1212584 NP_822086.1 CDS SAV_911 NC_003155.4 1090528 1091295 D PF00106: short chain dehydrogenase; dehydrogenase 1090528..1091295 Streptomyces avermitilis MA-4680 1212585 NP_822087.1 CDS pcpB NC_003155.4 1091689 1092819 R PF01360: Monooxygenase; pentachlorophenol 4-monooxygenase complement(1091689..1092819) Streptomyces avermitilis MA-4680 1212586 NP_822088.1 CDS SAV_913 NC_003155.4 1092937 1093518 D TetR family transcriptional regulator 1092937..1093518 Streptomyces avermitilis MA-4680 1212587 NP_822089.1 CDS SAV_914 NC_003155.4 1093703 1094287 D PF00582: Universal stress protein family; hypothetical protein 1093703..1094287 Streptomyces avermitilis MA-4680 1212588 NP_822090.1 CDS SAV_915 NC_003155.4 1094554 1094970 D hypothetical protein 1094554..1094970 Streptomyces avermitilis MA-4680 1212589 NP_822091.1 CDS lysA2 NC_003155.4 1094980 1096380 D PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain; diaminopimelate decarboxylase 1094980..1096380 Streptomyces avermitilis MA-4680 1210097 NP_822092.1 CDS kdpC NC_003155.4 1097100 1097768 R one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(1097100..1097768) Streptomyces avermitilis MA-4680 1210098 NP_822093.1 CDS kdpB NC_003155.4 1097793 1099877 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(1097793..1099877) Streptomyces avermitilis MA-4680 1210099 NP_822094.1 CDS kdpA NC_003155.4 1099967 1101631 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(1099967..1101631) Streptomyces avermitilis MA-4680 1210100 NP_822095.1 CDS SAV_920 NC_003155.4 1101987 1102472 R hypothetical protein complement(1101987..1102472) Streptomyces avermitilis MA-4680 1212590 NP_822096.1 CDS SAV_921 NC_003155.4 1102907 1103326 R PF01740: STAS domain; anti-sigma factor antagonist complement(1102907..1103326) Streptomyces avermitilis MA-4680 1212591 NP_822097.1 CDS prpC3 NC_003155.4 1103319 1104566 R PF00785: PAC motif; magnesium or manganese-dependent protein phosphatase complement(1103319..1104566) Streptomyces avermitilis MA-4680 1212592 NP_822098.1 CDS SAV_923 NC_003155.4 1104566 1105369 R PF00561: alpha/beta hydrolase fold; hydrolase complement(1104566..1105369) Streptomyces avermitilis MA-4680 1212593 NP_822099.1 CDS prpC4 NC_003155.4 1105704 1108190 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 1105704..1108190 Streptomyces avermitilis MA-4680 1212594 NP_822100.1 CDS SAV_925 NC_003155.4 1108453 1109142 D hypothetical protein 1108453..1109142 Streptomyces avermitilis MA-4680 1212595 NP_822101.1 CDS SAV_926 NC_003155.4 1109139 1119155 D a giant polypeptide 3338 aa; transcriptional activator SRCAP-like protein 1109139..1119155 Streptomyces avermitilis MA-4680 1212596 NP_822102.1 CDS SAV_927 NC_003155.4 1119155 1120723 D hypothetical protein 1119155..1120723 Streptomyces avermitilis MA-4680 1212597 NP_822103.1 CDS SAV_928 NC_003155.4 1120720 1121583 D hypothetical protein 1120720..1121583 Streptomyces avermitilis MA-4680 1212598 NP_822104.1 CDS SAV_929 NC_003155.4 1121580 1125176 D hypothetical protein 1121580..1125176 Streptomyces avermitilis MA-4680 1212599 NP_822105.1 CDS SAV_930 NC_003155.4 1125173 1127746 D N-acetylmuramoyl-L-alanine amidase 1125173..1127746 Streptomyces avermitilis MA-4680 1212600 NP_822106.1 CDS SAV_931 NC_003155.4 1127788 1128495 R two-component system response regulator complement(1127788..1128495) Streptomyces avermitilis MA-4680 1212601 NP_822107.1 CDS SAV_932 NC_003155.4 1128492 1129679 R two-component system sensor kinase complement(1128492..1129679) Streptomyces avermitilis MA-4680 1212602 NP_822108.1 CDS SAV_933 NC_003155.4 1129772 1130797 D ABC transporter ATP-binding protein 1129772..1130797 Streptomyces avermitilis MA-4680 1212603 NP_822109.1 CDS SAV_934 NC_003155.4 1130794 1131567 D ABC transporter permease 1130794..1131567 Streptomyces avermitilis MA-4680 1212604 NP_822110.1 CDS aveR NC_003155.4 1132045 1134894 D positive response regulator for avermectin biosynthetic gene cluster, avermectin gene cluster; LuxR family transcriptional regulator 1132045..1134894 Streptomyces avermitilis MA-4680 1210101 NP_822111.1 CDS aveF NC_003155.4 1134941 1135849 R avermectin gene cluster; C-5 ketoreductase complement(1134941..1135849) Streptomyces avermitilis MA-4680 1210102 NP_822112.1 CDS aveD NC_003155.4 1136629 1137480 R avermectin gene cluster; C5-O-methyltransferase complement(1136629..1137480) Streptomyces avermitilis MA-4680 1210103 NP_822113.1 CDS aveA1 NC_003155.4 1137817 1149735 D avermectin gene cluster; type I polyketide synthase AVES 1 1137817..1149735 Streptomyces avermitilis MA-4680 1210104 NP_822114.1 CDS aveA2 NC_003155.4 1149787 1168506 D avermectin gene cluster; type I polyketide synthase AVES 2 1149787..1168506 Streptomyces avermitilis MA-4680 1210105 NP_822115.1 CDS aveC NC_003155.4 1168503 1169546 D avermectin gene cluster; AveC 1168503..1169546 Streptomyces avermitilis MA-4680 1210106 NP_822116.1 CDS aveE NC_003155.4 1169630 1171000 R CYP171A1, avermectin gene cluster; cytochrome P450 hydroxylase complement(1169630..1171000) Streptomyces avermitilis MA-4680 1210107 NP_822117.1 CDS aveA3 NC_003155.4 1171152 1187750 R avermectin gene cluster; type I polyketide synthase AVES 3 complement(1171152..1187750) Streptomyces avermitilis MA-4680 1210108 NP_822118.1 CDS aveA4 NC_003155.4 1187928 1202573 R avermectin gene cluster; type I polyketide synthase AVES 4 complement(1187928..1202573) Streptomyces avermitilis MA-4680 1210109 NP_822119.1 CDS orf-1 NC_003155.4 1202833 1203546 D not involved in biosynthesis of avermectin, PF00106: short chain dehydrogenase; reductase 1202833..1203546 Streptomyces avermitilis MA-4680 1210110 NP_822120.1 CDS aveBI NC_003155.4 1203604 1204842 D avermectin gene cluster, PF00201: UDP-glucoronosyl and UDP-glucosyl transferase; glycosyl transferase 1203604..1204842 Streptomyces avermitilis MA-4680 1210111 NP_822121.1 CDS aveBII NC_003155.4 1204748 1205815 R avermectin gene cluster; dTDP-glucose 4,6-dehydratase complement(1204748..1205815) Streptomyces avermitilis MA-4680 1210112 NP_822122.1 CDS aveBIII NC_003155.4 1205812 1206711 R avermectin gene cluster; glucose-1-phosphate thymidyltransferase complement(1205812..1206711) Streptomyces avermitilis MA-4680 1210113 NP_822123.1 CDS aveBIV NC_003155.4 1206837 1207868 D avermectin gene cluster; dTDP-4-keto-6-deoxy-L-hexose 4-reductase 1206837..1207868 Streptomyces avermitilis MA-4680 1210114 NP_822124.1 CDS aveBV NC_003155.4 1207922 1208599 R avermectin gene cluster; dTDP-4-keto-6-deoxyhexose 3,5-epimerase complement(1207922..1208599) Streptomyces avermitilis MA-4680 1210115 NP_822125.1 CDS aveBVI NC_003155.4 1208661 1210070 R avermectin gene cluster; dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase complement(1208661..1210070) Streptomyces avermitilis MA-4680 1210116 NP_822126.1 CDS aveBVII NC_003155.4 1210067 1210840 R avermectin gene cluster; dTDP-6-deoxy-L-hexose 3-O-methyltransferase complement(1210067..1210840) Streptomyces avermitilis MA-4680 1210117 NP_822127.1 CDS aveBVIII NC_003155.4 1210927 1211970 R avermectin gene cluster; dTDP-4-keto-6-deoxy-L-hexose 2,3-reductase complement(1210927..1211970) Streptomyces avermitilis MA-4680 1210118 NP_822128.1 CDS aveG NC_003155.4 1212208 1212960 D avermectin gene cluster; thioesterase 1212208..1212960 Streptomyces avermitilis MA-4680 1210119 NP_822129.1 CDS yerD1 NC_003155.4 1213312 1214895 D glutamate synthase(ferredoxin) 1213312..1214895 Streptomyces avermitilis MA-4680 1210120 NP_822130.1 CDS poxB1 NC_003155.4 1214909 1216672 D PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors 1214909..1216672 Streptomyces avermitilis MA-4680 1212605 NP_822131.1 CDS prpB2 NC_003155.4 1216895 1218094 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(1216895..1218094) Streptomyces avermitilis MA-4680 1212606 NP_822132.1 CDS SAV_957 NC_003155.4 1218275 1218448 D PF05532: CsbD-like; hypothetical protein 1218275..1218448 Streptomyces avermitilis MA-4680 1212607 NP_822133.1 CDS SAV_958 NC_003155.4 1218971 1219141 D hypothetical protein 1218971..1219141 Streptomyces avermitilis MA-4680 1212608 NP_822134.1 CDS SAV_959 NC_003155.4 1219332 1219616 D hypothetical protein 1219332..1219616 Streptomyces avermitilis MA-4680 1212609 NP_822135.1 CDS SAV_960 NC_003155.4 1219827 1220234 D PF04946: DGPF domain; hypothetical protein 1219827..1220234 Streptomyces avermitilis MA-4680 1212610 NP_822136.1 CDS sig12 NC_003155.4 1220243 1221388 D ECF subfamily RNA polymerase sigma factor 1220243..1221388 Streptomyces avermitilis MA-4680 1210121 NP_822137.1 CDS SAV_962 NC_003155.4 1221488 1221802 D hypothetical protein 1221488..1221802 Streptomyces avermitilis MA-4680 1212611 NP_822138.1 CDS fdhA NC_003155.4 1222029 1223162 D PF00107: Zinc-binding dehydrogenase; glutathione-independent formaldehyde dehydrogenase 1222029..1223162 Streptomyces avermitilis MA-4680 1212612 NP_822139.1 CDS SAV_964 NC_003155.4 1223517 1223957 D PF02987: Late embryogenesis abundant protein; hypothetical protein 1223517..1223957 Streptomyces avermitilis MA-4680 1212613 NP_822140.1 CDS SAV_965 NC_003155.4 1224632 1225057 R PF01638: Transcriptional regulator; transcriptional regulator complement(1224632..1225057) Streptomyces avermitilis MA-4680 1212614 NP_822141.1 CDS SAV_966 NC_003155.4 1225192 1225653 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 1225192..1225653 Streptomyces avermitilis MA-4680 1212615 NP_822142.1 CDS SAV_967 NC_003155.4 1226230 1227438 R glycosyl hydrolase complement(1226230..1227438) Streptomyces avermitilis MA-4680 1212616 NP_822143.1 CDS SAV_968 NC_003155.4 1227720 1228718 R PF02653: Branched-chain amino acid transport system / permease component; ribose/xylose/arabinose/galactoside ABC transporter permease complement(1227720..1228718) Streptomyces avermitilis MA-4680 1212617 NP_822144.1 CDS SAV_969 NC_003155.4 1228751 1229716 R sugar ABC transporter permease complement(1228751..1229716) Streptomyces avermitilis MA-4680 1212618 NP_822145.1 CDS SAV_970 NC_003155.4 1229709 1231277 R sugar ABC transporter ATP-binding protein complement(1229709..1231277) Streptomyces avermitilis MA-4680 1212619 NP_822146.1 CDS SAV_971 NC_003155.4 1231383 1232498 R sugar ABC transporter periplasmic solute-binding protein complement(1231383..1232498) Streptomyces avermitilis MA-4680 1212620 NP_822147.1 CDS SAV_972 NC_003155.4 1232679 1233692 R LacI family transcriptional regulator complement(1232679..1233692) Streptomyces avermitilis MA-4680 1212621 NP_822148.1 CDS SAV_973 NC_003155.4 1233874 1236525 D PF07691: PA14 domain; hydrolase 1233874..1236525 Streptomyces avermitilis MA-4680 1212622 NP_822149.1 CDS SAV_974 NC_003155.4 1236913 1237734 D non-heme chloroperoxidase 1236913..1237734 Streptomyces avermitilis MA-4680 1212623 NP_822150.1 CDS pkn2 NC_003155.4 1238122 1239828 R serine/threonine protein kinase complement(1238122..1239828) Streptomyces avermitilis MA-4680 1210122 NP_822151.1 CDS SAV_976 NC_003155.4 1239936 1240271 D nucleotide-binding protein 1239936..1240271 Streptomyces avermitilis MA-4680 1212624 NP_822152.2 CDS SAV_977 NC_003155.4 1240310 1241584 D IS4 family transposase 1240310..1241584 Streptomyces avermitilis MA-4680 1212625 NP_822153.1 CDS SAV_978 NC_003155.4 1241684 1242469 R PF00665: Integrase core domain; transposase complement(1241684..1242469) Streptomyces avermitilis MA-4680 1212626 NP_822154.1 CDS SAV_979 NC_003155.4 1242469 1242702 R transposase complement(1242469..1242702) Streptomyces avermitilis MA-4680 1212627 YP_001621481.1 CDS SAV_7578 NC_003155.4 1242699 1243340 R hypothetical protein complement(1242699..1243340) Streptomyces avermitilis MA-4680 5815322 NP_822155.1 CDS SAV_980 NC_003155.4 1243471 1244862 D GntR family transcriptional regulator 1243471..1244862 Streptomyces avermitilis MA-4680 1212628 NP_822156.1 CDS SAV_981 NC_003155.4 1244924 1245541 D hypothetical protein 1244924..1245541 Streptomyces avermitilis MA-4680 1212629 NP_822157.1 CDS SAV_982 NC_003155.4 1245553 1245675 D hypothetical protein 1245553..1245675 Streptomyces avermitilis MA-4680 1212630 NP_822158.1 CDS SAV_983 NC_003155.4 1246455 1247330 D methyltransferase 1246455..1247330 Streptomyces avermitilis MA-4680 1212631 NP_822159.1 CDS SAV_984 NC_003155.4 1247421 1250234 R hypothetical protein complement(1247421..1250234) Streptomyces avermitilis MA-4680 1212632 NP_822160.1 CDS SAV_985 NC_003155.4 1250231 1251346 R PF00004: ATPase family associated with various cellular activities (AAA); hypothetical protein complement(1250231..1251346) Streptomyces avermitilis MA-4680 1212633 NP_822161.1 CDS SAV_986 NC_003155.4 1251356 1252792 R PF05762: VWA domain containing CoxE-like protein; hypothetical protein complement(1251356..1252792) Streptomyces avermitilis MA-4680 1212634 NP_822162.1 CDS SAV_987 NC_003155.4 1252789 1254189 R hypothetical protein complement(1252789..1254189) Streptomyces avermitilis MA-4680 1212635 NP_822163.1 CDS SAV_988 NC_003155.4 1254189 1254668 R hypothetical protein complement(1254189..1254668) Streptomyces avermitilis MA-4680 1212636 NP_822164.1 CDS SAV_989 NC_003155.4 1254946 1255869 D phosphotransferase 1254946..1255869 Streptomyces avermitilis MA-4680 1212637 NP_822165.1 CDS SAV_990 NC_003155.4 1256164 1256619 D protein 1256164..1256619 Streptomyces avermitilis MA-4680 1212638 NP_822166.1 CDS SAV_991 NC_003155.4 1257106 1257552 D hypothetical protein 1257106..1257552 Streptomyces avermitilis MA-4680 1212639 NP_822167.1 CDS SAV_992 NC_003155.4 1257609 1258790 D PF03631: Ribonuclease BN-like family; ribonuclease BN family membrane protein 1257609..1258790 Streptomyces avermitilis MA-4680 1212640 NP_822168.1 CDS SAV_993 NC_003155.4 1258992 1259420 R cysteine transferase complement(1258992..1259420) Streptomyces avermitilis MA-4680 1212641 NP_822169.1 CDS ptpA1 NC_003155.4 1259676 1260971 D conventional protein tyrosine phosphatase 1259676..1260971 Streptomyces avermitilis MA-4680 1212642 NP_822170.1 CDS SAV_995 NC_003155.4 1261279 1261713 R hypothetical protein complement(1261279..1261713) Streptomyces avermitilis MA-4680 1212643 NP_822171.1 CDS SAV_996 NC_003155.4 1262191 1262457 D hypothetical protein 1262191..1262457 Streptomyces avermitilis MA-4680 1212644 NP_822172.1 CDS sig13 NC_003155.4 1262450 1263121 D ECF subfamily RNA polymerase sigma factor 1262450..1263121 Streptomyces avermitilis MA-4680 1210123 NP_822173.1 CDS SAV_998 NC_003155.4 1263118 1264992 D PF01435: Peptidase family M48; hypothetical protein 1263118..1264992 Streptomyces avermitilis MA-4680 1212645 NP_822174.1 CDS SAV_999 NC_003155.4 1265082 1266182 R ATP-dependent carboxylate-amine ligase; carboxylate-amine ligase complement(1265082..1266182) Streptomyces avermitilis MA-4680 1212646 NP_822175.1 CDS sprC NC_003155.4 1266577 1267947 R PF00089: Trypsin; serine protease complement(1266577..1267947) Streptomyces avermitilis MA-4680 1210124 NP_822176.1 CDS SAV_1001 NC_003155.4 1268233 1269867 R PF01593: Flavin containing amine oxidoreductase; dehydrogenase complement(1268233..1269867) Streptomyces avermitilis MA-4680 1212647 NP_822177.1 CDS SAV_1002 NC_003155.4 1269949 1270425 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(1269949..1270425) Streptomyces avermitilis MA-4680 1212648 NP_822178.1 CDS SAV_1003 NC_003155.4 1270524 1271402 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(1270524..1271402) Streptomyces avermitilis MA-4680 1212649 NP_822179.1 CDS SAV_1004 NC_003155.4 1271761 1272111 D hypothetical protein 1271761..1272111 Streptomyces avermitilis MA-4680 1212650 NP_822180.1 CDS SAV_1005 NC_003155.4 1272152 1272571 R PF00571: CBS domain; oxidoreductase complement(1272152..1272571) Streptomyces avermitilis MA-4680 1212651 NP_822181.1 CDS SAV_1006 NC_003155.4 1272888 1273169 R PF04226: Transglycosylase associated protein; hypothetical protein complement(1272888..1273169) Streptomyces avermitilis MA-4680 1212652 NP_822182.1 CDS SAV_1007 NC_003155.4 1273736 1274263 D hypothetical protein 1273736..1274263 Streptomyces avermitilis MA-4680 1212653 NP_822183.1 CDS SAV_1008 NC_003155.4 1274688 1276823 D hypothetical protein 1274688..1276823 Streptomyces avermitilis MA-4680 1212654 NP_822184.1 CDS SAV_1009 NC_003155.4 1276910 1278451 D glycosyltransferase 1276910..1278451 Streptomyces avermitilis MA-4680 1212655 NP_822185.1 CDS SAV_1010 NC_003155.4 1278448 1279854 D hypothetical protein 1278448..1279854 Streptomyces avermitilis MA-4680 1212656 NP_822186.1 CDS galE5 NC_003155.4 1280007 1280801 D UDP-glucose 4-epimerase 1280007..1280801 Streptomyces avermitilis MA-4680 1210125 NP_822187.1 CDS SAV_1012 NC_003155.4 1280798 1281016 D hypothetical protein 1280798..1281016 Streptomyces avermitilis MA-4680 1212657 NP_822188.1 CDS mpg2 NC_003155.4 1281049 1281762 D mannose-1-phosphate guanyltransferase 1281049..1281762 Streptomyces avermitilis MA-4680 1210126 NP_822189.1 CDS SAV_1014 NC_003155.4 1281770 1282696 D NDP-hexose 4-ketoreductase 1281770..1282696 Streptomyces avermitilis MA-4680 1212658 NP_822190.1 CDS SAV_1015 NC_003155.4 1282693 1283355 D hypothetical protein 1282693..1283355 Streptomyces avermitilis MA-4680 1212659 NP_822191.1 CDS SAV_1016 NC_003155.4 1283443 1283901 R hypothetical protein complement(1283443..1283901) Streptomyces avermitilis MA-4680 1212660 NP_822192.1 CDS SAV_1017 NC_003155.4 1284066 1284428 D PF07300: Protein of unknown function (DUF1452); hypothetical protein 1284066..1284428 Streptomyces avermitilis MA-4680 1212661 NP_822193.1 CDS SAV_1018 NC_003155.4 1284484 1285032 R PF06532: Protein of unknown function (DUF1109); integral membrane protein complement(1284484..1285032) Streptomyces avermitilis MA-4680 1212662 NP_822194.1 CDS crtU NC_003155.4 1285187 1286689 R crt gene cluster, conversion of beta-carotene to isorenieratene; beta-carotene desaturase/methylase complement(1285187..1286689) Streptomyces avermitilis MA-4680 1210127 NP_822195.1 CDS crtT NC_003155.4 1286743 1287474 R crt gene cluster; methyltransferase complement(1286743..1287474) Streptomyces avermitilis MA-4680 1210128 NP_822196.1 CDS crtY NC_003155.4 1287518 1288711 R crt gene cluster; lycopene cyclase complement(1287518..1288711) Streptomyces avermitilis MA-4680 1210129 NP_822197.2 CDS crtE NC_003155.4 1289024 1290265 D crt gene cluster, probably geranylgeranyl pyrophosphate synthase; polyprenyl diphosphate synthase 1289024..1290265 Streptomyces avermitilis MA-4680 1210130 NP_822198.1 CDS crtI NC_003155.4 1290262 1291803 D crt gene cluster; phytoene desaturase 1290262..1291803 Streptomyces avermitilis MA-4680 1210131 NP_822199.1 CDS crtB NC_003155.4 1291800 1292828 D crt gene cluster; phytoene synthase 1291800..1292828 Streptomyces avermitilis MA-4680 1210132 NP_822200.1 CDS crtV NC_003155.4 1292825 1293904 D crt gene cluster; methylesterase 1292825..1293904 Streptomyces avermitilis MA-4680 1210133 NP_822201.1 CDS SAV_1026 NC_003155.4 1294125 1296224 R PF00652: QXW lectin repeat; protein complement(1294125..1296224) Streptomyces avermitilis MA-4680 1212663 NP_822202.1 CDS bga1 NC_003155.4 1296307 1298349 R beta-galactosidase complement(1296307..1298349) Streptomyces avermitilis MA-4680 1210134 NP_822203.1 CDS SAV_1028 NC_003155.4 1298401 1299738 R PF00497: Bacterial extracellular solute-binding proteins, family 3; solute-binding lipoprotein complement(1298401..1299738) Streptomyces avermitilis MA-4680 1212664 NP_822204.1 CDS SAV_1029 NC_003155.4 1299830 1300786 R ABC transporter permease complement(1299830..1300786) Streptomyces avermitilis MA-4680 1212665 NP_822205.1 CDS SAV_1030 NC_003155.4 1300791 1301717 R ABC transporter permease complement(1300791..1301717) Streptomyces avermitilis MA-4680 1212666 NP_822206.1 CDS SAV_1031 NC_003155.4 1301900 1302979 D LacI family transcriptional regulator 1301900..1302979 Streptomyces avermitilis MA-4680 1212667 NP_822207.1 CDS SAV_1032 NC_003155.4 1303150 1303467 D hypothetical protein 1303150..1303467 Streptomyces avermitilis MA-4680 1212668 NP_822208.1 CDS SAV_1033 NC_003155.4 1303909 1306188 D PF05976: Bacterial membrane protein of unknown function (DUF893); integral membrane protein 1303909..1306188 Streptomyces avermitilis MA-4680 1212669 NP_822209.1 CDS SAV_1034 NC_003155.4 1306217 1307035 R hypothetical protein complement(1306217..1307035) Streptomyces avermitilis MA-4680 1212670 NP_822210.1 CDS SAV_1035 NC_003155.4 1307347 1308420 R ATP-NAD kinase complement(1307347..1308420) Streptomyces avermitilis MA-4680 1212671 NP_822211.1 CDS SAV_1036 NC_003155.4 1308470 1309264 R PF00106: short chain dehydrogenase; dehydrogenase complement(1308470..1309264) Streptomyces avermitilis MA-4680 1212672 NP_822212.1 CDS SAV_1037 NC_003155.4 1309966 1312341 R PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease complement(1309966..1312341) Streptomyces avermitilis MA-4680 1212673 NP_822213.1 CDS hemC2 NC_003155.4 1312721 1313665 R porphobilinogen deaminase complement(1312721..1313665) Streptomyces avermitilis MA-4680 1210135 NP_822214.1 CDS SAV_1039 NC_003155.4 1313907 1314851 R PF00144: Beta-lactamase; hypothetical protein complement(1313907..1314851) Streptomyces avermitilis MA-4680 1212674 NP_822215.1 CDS SAV_1040 NC_003155.4 1315062 1315349 R hypothetical protein complement(1315062..1315349) Streptomyces avermitilis MA-4680 1212675 NP_822216.1 CDS SAV_1041 NC_003155.4 1315431 1316003 D hypothetical protein 1315431..1316003 Streptomyces avermitilis MA-4680 1212676 NP_822217.1 CDS SAV_1042 NC_003155.4 1316740 1318020 R PF07690: Major Facilitator Superfamily; hypothetical protein complement(1316740..1318020) Streptomyces avermitilis MA-4680 1212677 NP_822218.1 CDS SAV_1043 NC_003155.4 1318574 1320019 R alpha-arabinofuranosidase II complement(1318574..1320019) Streptomyces avermitilis MA-4680 1212678 NP_822219.1 CDS SAV_1044 NC_003155.4 1320038 1321573 R PF04616: Glycosyl hydrolases family 43; hydrolase complement(1320038..1321573) Streptomyces avermitilis MA-4680 1212679 NP_822220.1 CDS SAV_1045 NC_003155.4 1321655 1322329 R hypothetical protein complement(1321655..1322329) Streptomyces avermitilis MA-4680 1212680 NP_822221.1 CDS SAV_1046 NC_003155.4 1322480 1323022 R hypothetical protein complement(1322480..1323022) Streptomyces avermitilis MA-4680 1212681 NP_822222.1 CDS SAV_1047 NC_003155.4 1323552 1323782 D regulatory protein 1323552..1323782 Streptomyces avermitilis MA-4680 1212682 NP_822223.1 CDS SAV_1048 NC_003155.4 1323943 1324863 D DNA-binding protein 1323943..1324863 Streptomyces avermitilis MA-4680 1212683 NP_822224.1 CDS SAV_1049 NC_003155.4 1324945 1325763 R PF04672: Protein of unknown function (DUF574); hypothetical protein complement(1324945..1325763) Streptomyces avermitilis MA-4680 1212684 NP_822225.1 CDS SAV_1050 NC_003155.4 1325884 1326741 R PF00248: Aldo/keto reductase family; oxidoreductase complement(1325884..1326741) Streptomyces avermitilis MA-4680 1212685 NP_822226.1 CDS SAV_1051 NC_003155.4 1327109 1328002 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 1327109..1328002 Streptomyces avermitilis MA-4680 1212686 NP_822227.1 CDS SAV_1052 NC_003155.4 1328062 1328871 R PF04672: Protein of unknown function (DUF574); hypothetical protein complement(1328062..1328871) Streptomyces avermitilis MA-4680 1212687 NP_822228.1 CDS SAV_1053 NC_003155.4 1329176 1330375 D sugar hydrolase 1329176..1330375 Streptomyces avermitilis MA-4680 1212688 NP_822229.1 CDS prpJ4 NC_003155.4 1330445 1332496 R PF00989: PAS domain, PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(1330445..1332496) Streptomyces avermitilis MA-4680 1212689 NP_822230.1 CDS SAV_1055 NC_003155.4 1332766 1333503 R PF03861: ANTAR domain; hypothetical protein complement(1332766..1333503) Streptomyces avermitilis MA-4680 1212690 NP_822231.1 CDS SAV_1056 NC_003155.4 1333655 1334098 R MarR family transcriptional regulator complement(1333655..1334098) Streptomyces avermitilis MA-4680 1212691 NP_822232.1 CDS SAV_1057 NC_003155.4 1334264 1334701 R hypothetical protein complement(1334264..1334701) Streptomyces avermitilis MA-4680 1212692 NP_822233.1 CDS SAV_1058 NC_003155.4 1334840 1336405 R hypothetical protein complement(1334840..1336405) Streptomyces avermitilis MA-4680 1212693 NP_822234.1 CDS SAV_1059 NC_003155.4 1336683 1337606 D PF04471: Restriction endonuclease; hypothetical protein 1336683..1337606 Streptomyces avermitilis MA-4680 1212694 NP_822235.1 CDS SAV_1060 NC_003155.4 1337762 1338721 D PF03631: Ribonuclease BN-like family; ribonuclease BN 1337762..1338721 Streptomyces avermitilis MA-4680 1212695 NP_822236.1 CDS SAV_1061 NC_003155.4 1339060 1340271 R aminotransferase complement(1339060..1340271) Streptomyces avermitilis MA-4680 1212696 NP_822237.1 CDS SAV_1062 NC_003155.4 1340359 1341237 R hypothetical protein complement(1340359..1341237) Streptomyces avermitilis MA-4680 1212697 NP_822238.1 CDS SAV_1063 NC_003155.4 1341421 1341708 R hypothetical protein complement(1341421..1341708) Streptomyces avermitilis MA-4680 1212698 NP_822239.1 CDS SAV_1064 NC_003155.4 1342008 1343222 D phospholipase 1342008..1343222 Streptomyces avermitilis MA-4680 1212699 NP_822240.1 CDS SAV_1065 NC_003155.4 1343403 1344437 R PF00043: Glutathione S-transferase, C-terminal domain; hypothetical protein complement(1343403..1344437) Streptomyces avermitilis MA-4680 1212700 NP_822241.1 CDS SAV_1066 NC_003155.4 1344973 1345542 D hypothetical protein 1344973..1345542 Streptomyces avermitilis MA-4680 1212701 NP_822242.1 CDS SAV_1067 NC_003155.4 1345801 1346481 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(1345801..1346481) Streptomyces avermitilis MA-4680 1212702 NP_822243.1 CDS SAV_1068 NC_003155.4 1346651 1347208 D TetR family transcriptional regulator 1346651..1347208 Streptomyces avermitilis MA-4680 1212703 NP_822244.1 CDS SAV_1069 NC_003155.4 1347446 1348486 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(1347446..1348486) Streptomyces avermitilis MA-4680 1212704 NP_822245.1 CDS SAV_1070 NC_003155.4 1348483 1349763 R hypothetical protein complement(1348483..1349763) Streptomyces avermitilis MA-4680 1212705 NP_822246.1 CDS SAV_1071 NC_003155.4 1349760 1350932 R hypothetical protein complement(1349760..1350932) Streptomyces avermitilis MA-4680 1212706 NP_822247.1 CDS SAV_1072 NC_003155.4 1351064 1352230 D hypothetical protein 1351064..1352230 Streptomyces avermitilis MA-4680 1212707 NP_822248.1 CDS SAV_1073 NC_003155.4 1352542 1352922 D hypothetical protein 1352542..1352922 Streptomyces avermitilis MA-4680 1212708 NP_822249.1 CDS bcp1 NC_003155.4 1352919 1353386 D PF00578: AhpC/TSA family; bacterioferritin comigratory protein 1352919..1353386 Streptomyces avermitilis MA-4680 1210136 NP_822250.1 CDS SAV_1075 NC_003155.4 1353464 1354747 R PF00657: GDSL-like Lipase/Acylhydrolase; protein complement(1353464..1354747) Streptomyces avermitilis MA-4680 1212709 NP_822251.1 CDS SAV_1076 NC_003155.4 1354744 1357158 R hypothetical protein complement(1354744..1357158) Streptomyces avermitilis MA-4680 1212710 NP_822252.1 CDS SAV_1077 NC_003155.4 1357289 1359115 R melibiase complement(1357289..1359115) Streptomyces avermitilis MA-4680 1212711 NP_822253.1 CDS SAV_1078 NC_003155.4 1359193 1360014 R ABC transporter permease complement(1359193..1360014) Streptomyces avermitilis MA-4680 1212712 NP_822254.1 CDS SAV_1079 NC_003155.4 1360116 1361069 R ABC transporter permease complement(1360116..1361069) Streptomyces avermitilis MA-4680 1212713 NP_822255.1 CDS SAV_1080 NC_003155.4 1361096 1362439 R ABC transporter substrate-binding protein complement(1361096..1362439) Streptomyces avermitilis MA-4680 1212714 NP_822256.1 CDS SAV_1081 NC_003155.4 1362458 1363636 R transcriptional regulator complement(1362458..1363636) Streptomyces avermitilis MA-4680 1212715 NP_822257.1 CDS agaB1 NC_003155.4 1363816 1365948 D alpha-galactosidase 1363816..1365948 Streptomyces avermitilis MA-4680 1210137 NP_822258.1 CDS SAV_1083 NC_003155.4 1366037 1366684 R protein complement(1366037..1366684) Streptomyces avermitilis MA-4680 1212716 NP_822259.1 CDS SAV_1084 NC_003155.4 1367063 1367647 D hypothetical protein 1367063..1367647 Streptomyces avermitilis MA-4680 1212717 NP_822260.1 CDS SAV_1085 NC_003155.4 1368024 1372298 D two-component system sensor kinase 1368024..1372298 Streptomyces avermitilis MA-4680 1212718 NP_822261.1 CDS prpF NC_003155.4 1372393 1374891 D PF03861: ANTAR domain; magnesium or manganese-dependent protein phosphatase 1372393..1374891 Streptomyces avermitilis MA-4680 1212719 NP_822262.1 CDS sig14 NC_003155.4 1375028 1375915 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 1375028..1375915 Streptomyces avermitilis MA-4680 1210138 NP_822263.1 CDS SAV_1088 NC_003155.4 1375979 1376152 R PF05532: CsbD-like; hypothetical protein complement(1375979..1376152) Streptomyces avermitilis MA-4680 1212720 NP_822264.1 CDS SAV_1089 NC_003155.4 1376258 1376590 R hypothetical protein complement(1376258..1376590) Streptomyces avermitilis MA-4680 1212721 NP_822265.1 CDS SAV_1090 NC_003155.4 1376875 1377075 R hypothetical protein complement(1376875..1377075) Streptomyces avermitilis MA-4680 1212722 NP_822266.1 CDS SAV_1091 NC_003155.4 1377301 1377678 D PF01740: STAS domain; anti-sigma factor antagonist 1377301..1377678 Streptomyces avermitilis MA-4680 1212723 NP_822267.1 CDS SAV_1092 NC_003155.4 1377924 1378400 R MarR family transcriptional regulator complement(1377924..1378400) Streptomyces avermitilis MA-4680 1212724 NP_822268.1 CDS prpB3 NC_003155.4 1378554 1379741 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 1378554..1379741 Streptomyces avermitilis MA-4680 1212725 NP_822269.1 CDS rsbR NC_003155.4 1379931 1380830 D positive regulator 1379931..1380830 Streptomyces avermitilis MA-4680 1210139 NP_822270.1 CDS rsbS NC_003155.4 1380827 1381246 D PF01740: STAS domain; anti-sigma factor antagonist 1380827..1381246 Streptomyces avermitilis MA-4680 1210140 NP_822271.1 CDS rsbT NC_003155.4 1381294 1381689 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; anti-sigma factor 1381294..1381689 Streptomyces avermitilis MA-4680 1210141 NP_822272.1 CDS prpI2 NC_003155.4 1381686 1382759 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 1381686..1382759 Streptomyces avermitilis MA-4680 1212726 NP_822273.1 CDS prpB4 NC_003155.4 1382756 1384498 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 1382756..1384498 Streptomyces avermitilis MA-4680 1212727 NP_822274.1 CDS SAV_1099 NC_003155.4 1384489 1384995 R MarR family transcriptional regulator complement(1384489..1384995) Streptomyces avermitilis MA-4680 1212728 NP_822275.1 CDS SAV_1100 NC_003155.4 1385447 1385881 D regulatory protein 1385447..1385881 Streptomyces avermitilis MA-4680 1212729 NP_822276.1 CDS SAV_1101 NC_003155.4 1386020 1386520 R hypothetical protein complement(1386020..1386520) Streptomyces avermitilis MA-4680 1212730 NP_822277.1 CDS SAV_1102 NC_003155.4 1386577 1386972 R PF01740: STAS domain; anti-sigma factor antagonist complement(1386577..1386972) Streptomyces avermitilis MA-4680 1212731 NP_822278.1 CDS SAV_1103 NC_003155.4 1387458 1387943 R regulatory protein complement(1387458..1387943) Streptomyces avermitilis MA-4680 1212732 NP_822279.1 CDS fadD3 NC_003155.4 1388246 1390171 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase 1388246..1390171 Streptomyces avermitilis MA-4680 1210142 NP_822280.1 CDS SAV_1105 NC_003155.4 1390246 1390983 R hypothetical protein complement(1390246..1390983) Streptomyces avermitilis MA-4680 1212733 NP_822281.1 CDS SAV_1106 NC_003155.4 1391231 1392991 R PF02163: Peptidase family M50; hypothetical protein complement(1391231..1392991) Streptomyces avermitilis MA-4680 1212734 NP_822282.1 CDS SAV_1107 NC_003155.4 1393073 1393315 R hypothetical protein complement(1393073..1393315) Streptomyces avermitilis MA-4680 1212735 NP_822283.1 CDS SAV_1108 NC_003155.4 1393534 1393842 R hypothetical protein complement(1393534..1393842) Streptomyces avermitilis MA-4680 1212736 NP_822284.1 CDS SAV_1109 NC_003155.4 1393981 1394376 D hypothetical protein 1393981..1394376 Streptomyces avermitilis MA-4680 1212737 NP_822285.1 CDS SAV_1110 NC_003155.4 1394582 1394878 D hypothetical protein 1394582..1394878 Streptomyces avermitilis MA-4680 1212738 NP_822286.1 CDS SAV_1111 NC_003155.4 1395202 1396032 R PF04951: D-aminopeptidase; D-aminopeptidase complement(1395202..1396032) Streptomyces avermitilis MA-4680 1212739 NP_822287.1 CDS SAV_1112 NC_003155.4 1396223 1397143 D PF02668: Taurine catabolism dioxygenase TauD, TfdA family; taurine catabolism dioxygenase 1396223..1397143 Streptomyces avermitilis MA-4680 1212740 NP_822288.1 CDS SAV_1113 NC_003155.4 1397147 1397677 R hypothetical protein complement(1397147..1397677) Streptomyces avermitilis MA-4680 1212741 NP_822289.1 CDS SAV_1114 NC_003155.4 1397751 1398434 D hypothetical protein 1397751..1398434 Streptomyces avermitilis MA-4680 1212742 NP_822290.1 CDS SAV_1115 NC_003155.4 1398758 1400167 D arabinofuranosidase 1398758..1400167 Streptomyces avermitilis MA-4680 1212743 NP_822291.1 CDS SAV_1116 NC_003155.4 1400293 1402032 D PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; hypothetical protein 1400293..1402032 Streptomyces avermitilis MA-4680 1212744 NP_822292.1 CDS SAV_1117 NC_003155.4 1402053 1403417 R PF01433: Peptidase family M1; metallopeptidase complement(1402053..1403417) Streptomyces avermitilis MA-4680 1212745 NP_822293.1 CDS SAV_1118 NC_003155.4 1403619 1403963 D hypothetical protein 1403619..1403963 Streptomyces avermitilis MA-4680 1212746 NP_822294.1 CDS SAV_1119 NC_003155.4 1404364 1405710 R PF07690: Major Facilitator Superfamily; membrane transport protein complement(1404364..1405710) Streptomyces avermitilis MA-4680 1212747 NP_822295.1 CDS SAV_1120 NC_003155.4 1405778 1406389 R PF01810: LysE type translocator; hypothetical protein complement(1405778..1406389) Streptomyces avermitilis MA-4680 1212748 NP_822296.1 CDS SAV_1121 NC_003155.4 1406456 1407412 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 1406456..1407412 Streptomyces avermitilis MA-4680 1212749 NP_822297.1 CDS SAV_1122 NC_003155.4 1407714 1409957 D hypothetical protein 1407714..1409957 Streptomyces avermitilis MA-4680 1212750 NP_822298.1 CDS SAV_1123 NC_003155.4 1409996 1410571 D hypothetical protein 1409996..1410571 Streptomyces avermitilis MA-4680 1212751 NP_822299.1 CDS SAV_1124 NC_003155.4 1410593 1411429 R PF02743: Cache domain; hypothetical protein complement(1410593..1411429) Streptomyces avermitilis MA-4680 1212752 NP_822300.1 CDS SAV_1125 NC_003155.4 1411647 1412945 D ABC transporter 1411647..1412945 Streptomyces avermitilis MA-4680 1212753 NP_822301.1 CDS xylB2 NC_003155.4 1412969 1414465 R xylulose kinase complement(1412969..1414465) Streptomyces avermitilis MA-4680 1210143 NP_822302.1 CDS SAV_1127 NC_003155.4 1414635 1415312 D PF01987: Protein of unknown function DUF124; hypothetical protein 1414635..1415312 Streptomyces avermitilis MA-4680 1212754 NP_822303.1 CDS SAV_1128 NC_003155.4 1415378 1417162 R PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease complement(1415378..1417162) Streptomyces avermitilis MA-4680 1212755 NP_822304.1 CDS idsA1 NC_003155.4 1417491 1418525 R probably farnesyl pyrophosphate synthase; polyprenyl diphosphate synthase complement(1417491..1418525) Streptomyces avermitilis MA-4680 1210144 NP_822305.1 CDS SAV_1130 NC_003155.4 1418522 1419580 R PF00515: TPR Domain; hypothetical protein complement(1418522..1419580) Streptomyces avermitilis MA-4680 1212756 NP_822306.1 CDS SAV_1131 NC_003155.4 1419909 1420535 D alkylated DNA repair protein 1419909..1420535 Streptomyces avermitilis MA-4680 1212757 NP_822307.1 CDS SAV_1132 NC_003155.4 1420548 1421135 R TetR family transcriptional regulator complement(1420548..1421135) Streptomyces avermitilis MA-4680 1212758 NP_822308.1 CDS SAV_1133 NC_003155.4 1421141 1422697 R PF07690: Major Facilitator Superfamily; membrane transport protein complement(1421141..1422697) Streptomyces avermitilis MA-4680 1212759 NP_822309.1 CDS SAV_1134 NC_003155.4 1422761 1423966 R PF01360: Monooxygenase; hydroxylase complement(1422761..1423966) Streptomyces avermitilis MA-4680 1212760 NP_822310.1 CDS SAV_1135 NC_003155.4 1424120 1424587 D hypothetical protein 1424120..1424587 Streptomyces avermitilis MA-4680 1212761 NP_822311.1 CDS melC2 NC_003155.4 1424869 1425225 D melanin biosynthesis; tyrosinase co-factor protein 1424869..1425225 Streptomyces avermitilis MA-4680 1210145 NP_822312.1 CDS melC1 NC_003155.4 1425261 1426085 D melanin biosynthesis; tyrosinase 1425261..1426085 Streptomyces avermitilis MA-4680 1210146 NP_822313.1 CDS rnhA NC_003155.4 1426227 1426937 R PF00075: RNase H; ribonuclease H complement(1426227..1426937) Streptomyces avermitilis MA-4680 1212762 NP_822314.1 CDS SAV_1139 NC_003155.4 1427146 1427637 D PF01047: MarR family; hypothetical protein 1427146..1427637 Streptomyces avermitilis MA-4680 1212763 NP_822315.1 CDS SAV_1140 NC_003155.4 1427717 1428514 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hydroxylase complement(1427717..1428514) Streptomyces avermitilis MA-4680 1212764 NP_822316.1 CDS adhA1 NC_003155.4 1428660 1429664 D PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase 1428660..1429664 Streptomyces avermitilis MA-4680 1212765 NP_822317.1 CDS prpB5 NC_003155.4 1429684 1430985 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 1429684..1430985 Streptomyces avermitilis MA-4680 1212766 NP_822318.1 CDS SAV_1143 NC_003155.4 1431142 1432050 D hypothetical protein 1431142..1432050 Streptomyces avermitilis MA-4680 1212767 NP_822319.1 CDS SAV_1144 NC_003155.4 1432284 1434848 D PF02210: Laminin G domain; protein 1432284..1434848 Streptomyces avermitilis MA-4680 1212768 NP_822320.1 CDS SAV_1145 NC_003155.4 1434873 1435355 R DNA-binding protein complement(1434873..1435355) Streptomyces avermitilis MA-4680 1212769 NP_822321.1 CDS clpP4 NC_003155.4 1435653 1436306 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1435653..1436306 Streptomyces avermitilis MA-4680 1212770 NP_822322.1 CDS clpP5 NC_003155.4 1436308 1436910 D PF00574: Clp protease; ATP-dependent Clp protease proteolytic subunit 2 1436308..1436910 Streptomyces avermitilis MA-4680 1212771 NP_822323.1 CDS SAV_1148 NC_003155.4 1437000 1437455 R DNA-binding protein complement(1437000..1437455) Streptomyces avermitilis MA-4680 1212772 NP_822324.1 CDS SAV_1149 NC_003155.4 1437699 1439168 D PF01839: FG-GAP repeat; esterase 1437699..1439168 Streptomyces avermitilis MA-4680 1212773 NP_822325.1 CDS SAV_1150 NC_003155.4 1439316 1439543 D hypothetical protein 1439316..1439543 Streptomyces avermitilis MA-4680 1212774 NP_822326.1 CDS sig15 NC_003155.4 1439664 1440551 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 1439664..1440551 Streptomyces avermitilis MA-4680 1210147 NP_822327.1 CDS SAV_1152 NC_003155.4 1440671 1442164 R PF00781: Diacylglycerol kinase catalytic domain (presumed); hypothetical protein complement(1440671..1442164) Streptomyces avermitilis MA-4680 1212775 NP_822328.1 CDS SAV_1153 NC_003155.4 1442225 1442683 R regulatory protein complement(1442225..1442683) Streptomyces avermitilis MA-4680 1212776 NP_822329.1 CDS SAV_1154 NC_003155.4 1442897 1444327 R hypothetical protein complement(1442897..1444327) Streptomyces avermitilis MA-4680 1212777 NP_822330.1 CDS SAV_1155 NC_003155.4 1444480 1445736 D hypothetical protein 1444480..1445736 Streptomyces avermitilis MA-4680 1212778 NP_822331.1 CDS SAV_1156 NC_003155.4 1445834 1446853 D PF00296: Luciferase-like monooxygenase; monooxygenase 1445834..1446853 Streptomyces avermitilis MA-4680 1212779 NP_822332.1 CDS pkn3 NC_003155.4 1446863 1447837 R serine/threonine protein kinase complement(1446863..1447837) Streptomyces avermitilis MA-4680 1210148 NP_822333.1 CDS SAV_1158 NC_003155.4 1447837 1448433 R hypothetical protein complement(1447837..1448433) Streptomyces avermitilis MA-4680 1212780 NP_822334.1 CDS SAV_1159 NC_003155.4 1448439 1450781 R ABC transporter ATP-binding protein complement(1448439..1450781) Streptomyces avermitilis MA-4680 1212781 NP_822335.1 CDS SAV_1160 NC_003155.4 1450848 1451258 R hypothetical protein complement(1450848..1451258) Streptomyces avermitilis MA-4680 1212782 NP_822336.1 CDS SAV_1161 NC_003155.4 1451671 1452057 D isomerase 1451671..1452057 Streptomyces avermitilis MA-4680 1212783 NP_822337.1 CDS SAV_1162 NC_003155.4 1452141 1453103 R PF00248: Aldo/keto reductase family; ion channel subunit complement(1452141..1453103) Streptomyces avermitilis MA-4680 1212784 NP_822338.1 CDS SAV_1163 NC_003155.4 1453280 1454158 D LysR family transcriptional regulator 1453280..1454158 Streptomyces avermitilis MA-4680 1212785 NP_822339.1 CDS SAV_1164 NC_003155.4 1454314 1454829 D hypothetical protein 1454314..1454829 Streptomyces avermitilis MA-4680 1212786 NP_822340.1 CDS add1 NC_003155.4 1454811 1455875 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(1454811..1455875) Streptomyces avermitilis MA-4680 1210149 NP_822341.1 CDS SAV_1166 NC_003155.4 1455900 1456307 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(1455900..1456307) Streptomyces avermitilis MA-4680 1212787 NP_822342.1 CDS SAV_1167 NC_003155.4 1456484 1457401 R PF01435: Peptidase family M48; hypothetical protein complement(1456484..1457401) Streptomyces avermitilis MA-4680 1212788 NP_822343.1 CDS SAV_1168 NC_003155.4 1457398 1457769 R PF01047: MarR family; hypothetical protein complement(1457398..1457769) Streptomyces avermitilis MA-4680 1212789 NP_822344.1 CDS SAV_1169 NC_003155.4 1457969 1458820 D PF01569: PAP2 superfamily; hypothetical protein 1457969..1458820 Streptomyces avermitilis MA-4680 1212790 NP_822345.1 CDS SAV_1170 NC_003155.4 1458666 1459718 D PF01758: Sodium Bile acid symporter family; sodium-dependent transporter 1458666..1459718 Streptomyces avermitilis MA-4680 1212791 NP_822346.1 CDS cyp5 NC_003155.4 1460052 1461257 R CYP107F2; cytochrome P450 complement(1460052..1461257) Streptomyces avermitilis MA-4680 1210150 NP_822347.1 CDS SAV_1172 NC_003155.4 1461860 1462783 R PF00248: Aldo/keto reductase family; oxidoreductase complement(1461860..1462783) Streptomyces avermitilis MA-4680 1212792 NP_822348.1 CDS SAV_1173 NC_003155.4 1462809 1464203 R hypothetical protein complement(1462809..1464203) Streptomyces avermitilis MA-4680 1212793 NP_822349.1 CDS SAV_1174 NC_003155.4 1464641 1465246 D hypothetical protein 1464641..1465246 Streptomyces avermitilis MA-4680 1212794 NP_822350.1 CDS SAV_1175 NC_003155.4 1465703 1466494 R hypothetical protein complement(1465703..1466494) Streptomyces avermitilis MA-4680 1212795 NP_822351.1 CDS SAV_1176 NC_003155.4 1466669 1466827 R hypothetical protein complement(1466669..1466827) Streptomyces avermitilis MA-4680 1212796 NP_822352.1 CDS SAV_1177 NC_003155.4 1466876 1468402 R Activates fatty acids by binding to coenzyme A; acyl-CoA synthase complement(1466876..1468402) Streptomyces avermitilis MA-4680 1212797 NP_822353.1 CDS pabAB NC_003155.4 1468399 1470597 R similar to Streptomyces griseus pabAB; para-aminobenzoic acid synthase complement(1468399..1470597) Streptomyces avermitilis MA-4680 1210151 NP_822354.1 CDS SAV_1179 NC_003155.4 1470594 1471157 R hypothetical protein complement(1470594..1471157) Streptomyces avermitilis MA-4680 1212798 NP_822355.1 CDS SAV_1180 NC_003155.4 1471456 1473141 D PF05547: Immune inhibitor A peptidase M6; protease 1471456..1473141 Streptomyces avermitilis MA-4680 1212799 NP_822356.1 CDS SAV_1181 NC_003155.4 1473145 1473453 D hypothetical protein 1473145..1473453 Streptomyces avermitilis MA-4680 1212800 NP_822357.1 CDS SAV_1182 NC_003155.4 1473954 1474355 D hypothetical protein 1473954..1474355 Streptomyces avermitilis MA-4680 1212801 NP_822358.1 CDS SAV_1183 NC_003155.4 1474359 1474949 R PF04264: YceI like family; hypothetical protein complement(1474359..1474949) Streptomyces avermitilis MA-4680 1212802 NP_822359.1 CDS SAV_1184 NC_003155.4 1475033 1475533 D MarR family transcriptional regulator 1475033..1475533 Streptomyces avermitilis MA-4680 1212803 NP_822360.1 CDS SAV_1185 NC_003155.4 1475897 1476667 R LysR family trancsriptional regulator complement(1475897..1476667) Streptomyces avermitilis MA-4680 1212804 NP_822361.1 CDS SAV_1186 NC_003155.4 1476726 1477133 D hypothetical protein 1476726..1477133 Streptomyces avermitilis MA-4680 1212805 NP_822362.1 CDS aldH NC_003155.4 1477301 1478626 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(1477301..1478626) Streptomyces avermitilis MA-4680 1210152 NP_822363.1 CDS amiA NC_003155.4 1478786 1479250 R MarR family transcriptional regulator complement(1478786..1479250) Streptomyces avermitilis MA-4680 1212806 NP_822364.1 CDS SAV_1189 NC_003155.4 1479316 1480428 D regulatory protein 1479316..1480428 Streptomyces avermitilis MA-4680 1212807 NP_822365.1 CDS SAV_1190 NC_003155.4 1480655 1481956 D ABC transporter substrate-binding protein 1480655..1481956 Streptomyces avermitilis MA-4680 1212808 NP_822366.1 CDS SAV_1191 NC_003155.4 1482024 1482920 D branched-chain amino acid ABC transporter permease 1482024..1482920 Streptomyces avermitilis MA-4680 1212809 NP_822367.1 CDS SAV_1192 NC_003155.4 1482917 1484026 D branched-chain amino acid ABC transporter permease 1482917..1484026 Streptomyces avermitilis MA-4680 1212810 NP_822368.1 CDS SAV_1193 NC_003155.4 1484023 1484829 D ABC transporter ATP-binding protein 1484023..1484829 Streptomyces avermitilis MA-4680 1212811 NP_822369.1 CDS SAV_1194 NC_003155.4 1484829 1485521 D ABC transporter ATP-binding protein 1484829..1485521 Streptomyces avermitilis MA-4680 1212812 NP_822370.1 CDS sig16 NC_003155.4 1485526 1486716 R ECF subfamily RNA polymerase sigma factor complement(1485526..1486716) Streptomyces avermitilis MA-4680 1210153 NP_822371.1 CDS SAV_1196 NC_003155.4 1486716 1487108 R PF04946: DGPF domain; hypothetical protein complement(1486716..1487108) Streptomyces avermitilis MA-4680 1212813 NP_822372.1 CDS SAV_1197 NC_003155.4 1487174 1488235 D PF02771: Acyl-CoA dehydrogenase, N-terminal domain; hypothetical protein 1487174..1488235 Streptomyces avermitilis MA-4680 1212814 NP_822373.1 CDS SAV_1198 NC_003155.4 1488724 1488921 D IS630 family, partial; IS630 family transposase 1488724..1488921 Streptomyces avermitilis MA-4680 1212815 NP_822374.1 CDS SAV_1199 NC_003155.4 1488976 1490019 R AraC family transcription regulator complement(1488976..1490019) Streptomyces avermitilis MA-4680 1212816 NP_822375.1 CDS SAV_1200 NC_003155.4 1490156 1491082 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 1490156..1491082 Streptomyces avermitilis MA-4680 1212817 NP_822376.1 CDS SAV_1201 NC_003155.4 1491478 1492473 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 1491478..1492473 Streptomyces avermitilis MA-4680 1212818 NP_822377.1 CDS SAV_1202 NC_003155.4 1492522 1493124 D TetR family transcriptional regulator 1492522..1493124 Streptomyces avermitilis MA-4680 1212819 NP_822378.1 CDS SAV_1203 NC_003155.4 1493561 1493815 R hypothetical protein complement(1493561..1493815) Streptomyces avermitilis MA-4680 1212820 NP_822379.2 CDS SAV_1204 NC_003155.4 1493973 1495142 R IS630 family transposase complement(1493973..1495142) Streptomyces avermitilis MA-4680 1212821 NP_822380.1 CDS ssuD1 NC_003155.4 1495178 1496359 R PF00296: Luciferase-like monooxygenase; alkanesulfonate monooxygenase complement(1495178..1496359) Streptomyces avermitilis MA-4680 1212822 NP_822381.1 CDS SAV_1206 NC_003155.4 1496417 1497601 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(1496417..1497601) Streptomyces avermitilis MA-4680 1212823 NP_822382.1 CDS SAV_1207 NC_003155.4 1497607 1498161 R PF03358: NADPH-dependent FMN reductase; NAD(P)H-dependent FMN reductase complement(1497607..1498161) Streptomyces avermitilis MA-4680 1212824 NP_822383.1 CDS SAV_1208 NC_003155.4 1498327 1499448 R PF00296: Luciferase-like monooxygenase; monooxygenase complement(1498327..1499448) Streptomyces avermitilis MA-4680 1212825 NP_822384.1 CDS SAV_1209 NC_003155.4 1499955 1500875 D LysR family transcriptional regulator 1499955..1500875 Streptomyces avermitilis MA-4680 1212826 NP_822385.1 CDS SAV_1210 NC_003155.4 1500906 1501055 D hypothetical protein 1500906..1501055 Streptomyces avermitilis MA-4680 1212827 NP_822386.1 CDS SAV_1211 NC_003155.4 1501530 1503104 D PF01073: 3-beta-hydroxysteroid dehydrogenase/isomerase family; oxidoreductase 1501530..1503104 Streptomyces avermitilis MA-4680 1212828 NP_822387.1 CDS phrB NC_003155.4 1503492 1504865 D deoxyribodipyrimidine photolyase 1503492..1504865 Streptomyces avermitilis MA-4680 1210154 NP_822388.1 CDS SAV_1213 NC_003155.4 1504925 1506178 R PF01593: Flavin containing amine oxidoreductase; oxidoreductase complement(1504925..1506178) Streptomyces avermitilis MA-4680 1212829 NP_822389.1 CDS SAV_1214 NC_003155.4 1506484 1507527 R probably regulates carotenoid biosynthesis; transcriptional regulator complement(1506484..1507527) Streptomyces avermitilis MA-4680 1212830 NP_822390.1 CDS sig17 NC_003155.4 1507710 1508324 D probably regulates carotenoid biosynthesis; ECF subfamily RNA polymerase sigma factor 1507710..1508324 Streptomyces avermitilis MA-4680 1210155 NP_822391.1 CDS SAV_1216 NC_003155.4 1508862 1509881 D PF03631: Ribonuclease BN-like family; ribonuclease BN family membrane protein 1508862..1509881 Streptomyces avermitilis MA-4680 1212831 NP_822392.1 CDS blaB2 NC_003155.4 1509820 1510692 R PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase complement(1509820..1510692) Streptomyces avermitilis MA-4680 1210156 NP_822393.1 CDS SAV_1218 NC_003155.4 1510755 1511354 D TetR family transcriptional regulator 1510755..1511354 Streptomyces avermitilis MA-4680 1212832 NP_822394.1 CDS SAV_1219 NC_003155.4 1511493 1511933 D PF03779: SPW repeat; hypothetical protein 1511493..1511933 Streptomyces avermitilis MA-4680 1212833 NP_822395.1 CDS SAV_1220 NC_003155.4 1512151 1513404 D PF01636: Phosphotransferase enzyme family; hypothetical protein 1512151..1513404 Streptomyces avermitilis MA-4680 1212834 NP_822396.1 CDS SAV_1221 NC_003155.4 1513650 1515119 R amino acid permease complement(1513650..1515119) Streptomyces avermitilis MA-4680 1212835 NP_822397.1 CDS SAV_1222 NC_003155.4 1515303 1516502 D transcriptional regulator 1515303..1516502 Streptomyces avermitilis MA-4680 1212836 NP_822398.1 CDS SAV_1223 NC_003155.4 1516617 1519331 D beta-mannosidase 1516617..1519331 Streptomyces avermitilis MA-4680 1212837 NP_822399.1 CDS SAV_1224 NC_003155.4 1519410 1520858 R hydrolase complement(1519410..1520858) Streptomyces avermitilis MA-4680 1212838 NP_822400.1 CDS SAV_1225 NC_003155.4 1521090 1521353 D transglycosylase associated protein 1521090..1521353 Streptomyces avermitilis MA-4680 1212839 NP_822401.1 CDS SAV_1226 NC_003155.4 1521511 1522497 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 1521511..1522497 Streptomyces avermitilis MA-4680 1212840 NP_822402.1 CDS SAV_1227 NC_003155.4 1522627 1523400 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(1522627..1523400) Streptomyces avermitilis MA-4680 1212841 NP_822403.1 CDS SAV_1228 NC_003155.4 1523648 1524178 D possible transporter; hypothetical protein 1523648..1524178 Streptomyces avermitilis MA-4680 1212842 NP_822404.1 CDS SAV_1229 NC_003155.4 1524392 1525243 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(1524392..1525243) Streptomyces avermitilis MA-4680 1212843 NP_822405.1 CDS SAV_1230 NC_003155.4 1525501 1526181 R PF03777: Small domain (DUF320); protein complement(1525501..1526181) Streptomyces avermitilis MA-4680 1212844 NP_822406.1 CDS SAV_1231 NC_003155.4 1526437 1528074 D PF00561: alpha/beta hydrolase fold; protease 1526437..1528074 Streptomyces avermitilis MA-4680 1212845 NP_822407.1 CDS yerD2 NC_003155.4 1528178 1529773 D glutamate synthase(ferredoxin) 1528178..1529773 Streptomyces avermitilis MA-4680 1210157 NP_822408.1 CDS SAV_1233 NC_003155.4 1529952 1531049 D PF03465: eRF1 domain 3; hypothetical protein 1529952..1531049 Streptomyces avermitilis MA-4680 1212846 NP_822409.1 CDS iolG NC_003155.4 1531131 1532162 D inositol metabolism, PF01408: Oxidoreductase family, NAD-binding Rossmann fold; myo-inositol 2-dehydrogenase 1531131..1532162 Streptomyces avermitilis MA-4680 1210158 NP_822410.1 CDS prpC5 NC_003155.4 1532453 1533922 D PF00785: PAC motif; magnesium or manganese-dependent protein phosphatase 1532453..1533922 Streptomyces avermitilis MA-4680 1212847 NP_822411.1 CDS SAV_1236 NC_003155.4 1534044 1535540 R regulatory protein complement(1534044..1535540) Streptomyces avermitilis MA-4680 1212848 NP_822412.1 CDS SAV_1237 NC_003155.4 1535774 1536916 D PF01636: Phosphotransferase enzyme family; hypothetical protein 1535774..1536916 Streptomyces avermitilis MA-4680 1212849 NP_822413.1 CDS SAV_1238 NC_003155.4 1537201 1539180 D amidase 1537201..1539180 Streptomyces avermitilis MA-4680 1212850 NP_822414.1 CDS SAV_1239 NC_003155.4 1539243 1539740 R hypothetical protein complement(1539243..1539740) Streptomyces avermitilis MA-4680 1212851 NP_822415.1 CDS SAV_1240 NC_003155.4 1540024 1540284 D hypothetical protein 1540024..1540284 Streptomyces avermitilis MA-4680 1212852 NP_822416.1 CDS SAV_1241 NC_003155.4 1540468 1540710 R homology to bldB, PF04149: Domain of unknown function (DUF397); hypothetical protein complement(1540468..1540710) Streptomyces avermitilis MA-4680 1212853 NP_822417.1 CDS SAV_1242 NC_003155.4 1540794 1541960 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(1540794..1541960) Streptomyces avermitilis MA-4680 1212854 NP_822418.1 CDS SAV_1243 NC_003155.4 1541957 1543006 R lipid-transfer protein complement(1541957..1543006) Streptomyces avermitilis MA-4680 1212855 NP_822419.1 CDS SAV_1244 NC_003155.4 1543003 1543923 R PF01796: Domain of unknown function DUF35; hypothetical protein complement(1543003..1543923) Streptomyces avermitilis MA-4680 1212856 NP_822420.1 CDS echA4 NC_003155.4 1543977 1544753 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1543977..1544753) Streptomyces avermitilis MA-4680 1210159 NP_822421.1 CDS fadD4 NC_003155.4 1544829 1546583 D activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; acyl-CoA synthetase 1544829..1546583 Streptomyces avermitilis MA-4680 1210160 NP_822422.1 CDS cpdA NC_003155.4 1546700 1547473 D cyclic nucleotide phosphodiesterase 1546700..1547473 Streptomyces avermitilis MA-4680 1210161 NP_822423.1 CDS SAV_1248 NC_003155.4 1547571 1548623 R PF01590: GAF domain; hypothetical protein complement(1547571..1548623) Streptomyces avermitilis MA-4680 1212857 NP_822424.1 CDS SAV_1249 NC_003155.4 1549424 1551430 D nrps8 gene cluster; modular polyketide synthase 1549424..1551430 Streptomyces avermitilis MA-4680 1212858 NP_822425.1 CDS nrps8 NC_003155.4 1551427 1552974 D nrps8 gene cluster; non-ribosomal peptide synthetase 1551427..1552974 Streptomyces avermitilis MA-4680 1212859 NP_822426.1 CDS SAV_1251 NC_003155.4 1553040 1554224 D nrps8 gene cluster; hydroxylase 1553040..1554224 Streptomyces avermitilis MA-4680 1212860 NP_822427.1 CDS cvnA1 NC_003155.4 1554555 1557221 D multi-component regulatory system-1; sensor-like histidine kinase 1554555..1557221 Streptomyces avermitilis MA-4680 1210162 NP_822428.1 CDS cvnB1 NC_003155.4 1557218 1557667 D multi-component regulatory system-1, PF03259: Roadblock/LC7 domain; hypothetical protein 1557218..1557667 Streptomyces avermitilis MA-4680 1210163 NP_822429.1 CDS cvnC1 NC_003155.4 1557660 1558034 D multi-component regulatory system-1, PF05331: Protein of unknown function (DUF742); hypothetical protein 1557660..1558034 Streptomyces avermitilis MA-4680 1210164 NP_822430.1 CDS cvnD1 NC_003155.4 1558015 1558614 D multi-component regulatory system-1; ATP/GTP-binding protein 1558015..1558614 Streptomyces avermitilis MA-4680 1210165 NP_822431.1 CDS SAV_1256 NC_003155.4 1558633 1559469 R PF00561: alpha/beta hydrolase fold; hydrolase complement(1558633..1559469) Streptomyces avermitilis MA-4680 1212861 NP_822432.1 CDS paaK NC_003155.4 1559656 1560951 D phenylacetate:CoA ligase 1559656..1560951 Streptomyces avermitilis MA-4680 1210166 NP_822433.1 CDS fadD5 NC_003155.4 1561000 1562499 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(1561000..1562499) Streptomyces avermitilis MA-4680 1210167 NP_822434.1 CDS fadD6 NC_003155.4 1562796 1564346 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1562796..1564346) Streptomyces avermitilis MA-4680 1210168 NP_822435.1 CDS SAV_1260 NC_003155.4 1564343 1565452 R PF03060: 2-nitropropane dioxygenase; dioxygenase complement(1564343..1565452) Streptomyces avermitilis MA-4680 1212862 NP_822436.1 CDS blaA1 NC_003155.4 1565622 1567469 D PF00144: Beta-lactamase; beta-lactamase 1565622..1567469 Streptomyces avermitilis MA-4680 1210169 NP_822437.1 CDS SAV_1262 NC_003155.4 1567506 1568018 D hypothetical protein 1567506..1568018 Streptomyces avermitilis MA-4680 1212863 NP_822438.1 CDS SAV_1263 NC_003155.4 1568444 1569079 R TetR family transcriptional regulator complement(1568444..1569079) Streptomyces avermitilis MA-4680 1212864 NP_822439.1 CDS SAV_1264 NC_003155.4 1569085 1570686 R PF01593: Flavin containing amine oxidoreductase; oxidoreductase complement(1569085..1570686) Streptomyces avermitilis MA-4680 1212865 NP_822440.1 CDS pkn4 NC_003155.4 1570968 1573232 R serine/threonine protein kinase complement(1570968..1573232) Streptomyces avermitilis MA-4680 1210170 NP_822441.1 CDS SAV_1266 NC_003155.4 1573293 1574150 R hypothetical protein complement(1573293..1574150) Streptomyces avermitilis MA-4680 1212866 NP_822442.1 CDS fadE14 NC_003155.4 1574160 1575338 R PF02770: Acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase complement(1574160..1575338) Streptomyces avermitilis MA-4680 1210171 NP_822443.1 CDS SAV_1268 NC_003155.4 1575577 1576035 R PF03860: Domain of Unknown Function (DUF326); hypothetical protein complement(1575577..1576035) Streptomyces avermitilis MA-4680 1212867 NP_822444.1 CDS SAV_1269 NC_003155.4 1576268 1576669 R hypothetical protein complement(1576268..1576669) Streptomyces avermitilis MA-4680 1212868 NP_822445.1 CDS SAV_1270 NC_003155.4 1576753 1577319 D PadR-like family transcriptional regulator 1576753..1577319 Streptomyces avermitilis MA-4680 1212869 NP_822446.1 CDS SAV_1271 NC_003155.4 1577424 1578050 R DNA-binding protein complement(1577424..1578050) Streptomyces avermitilis MA-4680 1212870 NP_822447.1 CDS SAV_1272 NC_003155.4 1578130 1579200 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(1578130..1579200) Streptomyces avermitilis MA-4680 1212871 NP_822448.1 CDS SAV_1273 NC_003155.4 1579336 1581717 R PF03894: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; putative phosphoketolase complement(1579336..1581717) Streptomyces avermitilis MA-4680 1212872 NP_822449.1 CDS SAV_1274 NC_003155.4 1581753 1582556 D regulatory protein 1581753..1582556 Streptomyces avermitilis MA-4680 1212873 NP_822450.1 CDS SAV_1275 NC_003155.4 1582571 1583443 R stress-inducible protein complement(1582571..1583443) Streptomyces avermitilis MA-4680 1212874 NP_822451.1 CDS SAV_1276 NC_003155.4 1583527 1583880 R hypothetical protein complement(1583527..1583880) Streptomyces avermitilis MA-4680 1212875 NP_822452.1 CDS SAV_1277 NC_003155.4 1583840 1586992 R PF05729: NACHT domain; hypothetical protein complement(1583840..1586992) Streptomyces avermitilis MA-4680 1212876 NP_822453.1 CDS SAV_1278 NC_003155.4 1587146 1587679 D PF00027: Cyclic nucleotide-binding domain; CRP-like regulatory protein 1587146..1587679 Streptomyces avermitilis MA-4680 1212877 NP_822454.1 CDS SAV_1279 NC_003155.4 1587800 1588627 D PF04672: Protein of unknown function (DUF574); hypothetical protein 1587800..1588627 Streptomyces avermitilis MA-4680 1212878 NP_822455.1 CDS SAV_1280 NC_003155.4 1588857 1589567 R PF00106: short chain dehydrogenase; dehydrogenase complement(1588857..1589567) Streptomyces avermitilis MA-4680 1212879 NP_822456.1 CDS SAV_1281 NC_003155.4 1589771 1590874 R two-component system sensor kinase complement(1589771..1590874) Streptomyces avermitilis MA-4680 1212880 NP_822457.1 CDS SAV_1282 NC_003155.4 1590871 1591551 R two-component system response regulator complement(1590871..1591551) Streptomyces avermitilis MA-4680 1212881 NP_822458.1 CDS SAV_1283 NC_003155.4 1591712 1592941 D PF04235: Protein of unknown function (DUF418); hypothetical protein 1591712..1592941 Streptomyces avermitilis MA-4680 1212882 NP_822459.1 CDS SAV_1284 NC_003155.4 1593064 1593717 D PF00300: Phosphoglycerate mutase family; hypothetical protein 1593064..1593717 Streptomyces avermitilis MA-4680 1212883 NP_822460.1 CDS dak1 NC_003155.4 1594134 1595126 D with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1594134..1595126 Streptomyces avermitilis MA-4680 1210172 NP_822461.1 CDS dak2 NC_003155.4 1595172 1595771 D PF02734: Dak2 domain; dihydroxyacetone kinase subunit 2 1595172..1595771 Streptomyces avermitilis MA-4680 1210173 NP_822462.1 CDS SAV_1287 NC_003155.4 1595764 1596180 D PF03610: PTS system fructose IIA component; dihydroxyacetone kinase phosphotransfer protein 1595764..1596180 Streptomyces avermitilis MA-4680 1212884 NP_822463.1 CDS SAV_1288 NC_003155.4 1596355 1597128 R PF07335: Fungal chitosanase; protein complement(1596355..1597128) Streptomyces avermitilis MA-4680 1212885 NP_822464.1 CDS SAV_1289 NC_003155.4 1597420 1598451 D PF00041: Fibronectin type III domain; sugar hydrolase 1597420..1598451 Streptomyces avermitilis MA-4680 1212886 NP_822465.1 CDS SAV_1290 NC_003155.4 1598664 1599200 D hypothetical protein 1598664..1599200 Streptomyces avermitilis MA-4680 1212887 NP_822466.1 CDS SAV_1291 NC_003155.4 1599274 1599819 R PadR-like family transcriptional regulator complement(1599274..1599819) Streptomyces avermitilis MA-4680 1212888 NP_822467.1 CDS fadH NC_003155.4 1599862 1601877 R PF00724: NADH:flavin oxidoreductase / NADH oxidase family; 2,4-dienoyl-CoA reductase complement(1599862..1601877) Streptomyces avermitilis MA-4680 1210174 NP_822468.1 CDS SAV_1293 NC_003155.4 1602176 1602994 R methyltransferase complement(1602176..1602994) Streptomyces avermitilis MA-4680 1212889 NP_822469.1 CDS SAV_1294 NC_003155.4 1603173 1604291 R hypothetical protein complement(1603173..1604291) Streptomyces avermitilis MA-4680 1212890 NP_822470.1 CDS SAV_1295 NC_003155.4 1604339 1604869 D MarR family transcriptional regulator 1604339..1604869 Streptomyces avermitilis MA-4680 1212891 NP_822471.1 CDS SAV_1296 NC_003155.4 1604909 1605814 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(1604909..1605814) Streptomyces avermitilis MA-4680 1212892 NP_822472.1 CDS SAV_1297 NC_003155.4 1605811 1606731 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(1605811..1606731) Streptomyces avermitilis MA-4680 1212893 NP_822473.1 CDS SAV_1298 NC_003155.4 1606980 1607585 D PF00174: Oxidoreductase molybdopterin binding domain; hypothetical protein 1606980..1607585 Streptomyces avermitilis MA-4680 1212894 NP_822474.1 CDS SAV_1299 NC_003155.4 1607578 1608333 D PF00970: Oxidoreductase FAD-binding domain; oxidoreductase 1607578..1608333 Streptomyces avermitilis MA-4680 1212895 NP_822475.1 CDS SAV_1300 NC_003155.4 1608351 1609238 R stress-inducible protein complement(1608351..1609238) Streptomyces avermitilis MA-4680 1212896 NP_822476.1 CDS SAV_1301 NC_003155.4 1609344 1610210 D hypothetical protein 1609344..1610210 Streptomyces avermitilis MA-4680 1212897 NP_822477.1 CDS axe1 NC_003155.4 1610532 1611500 D PF05448: Acetyl xylan esterase (AXE1); acetyl xylan esterase 1610532..1611500 Streptomyces avermitilis MA-4680 1210175 NP_822478.1 CDS SAV_1303 NC_003155.4 1611497 1611916 D hypothetical protein 1611497..1611916 Streptomyces avermitilis MA-4680 1212898 NP_822479.1 CDS SAV_1304 NC_003155.4 1612092 1613258 D esterase 1612092..1613258 Streptomyces avermitilis MA-4680 1212899 NP_822480.1 CDS SAV_1305 NC_003155.4 1613379 1614131 D GntR family transcriptional regulator 1613379..1614131 Streptomyces avermitilis MA-4680 1212900 NP_822481.1 CDS SAV_1306 NC_003155.4 1614307 1615050 R methyltransferase complement(1614307..1615050) Streptomyces avermitilis MA-4680 1212901 NP_822482.1 CDS dexA NC_003155.4 1615206 1616795 D oligo-1,6-glucosidase 1615206..1616795 Streptomyces avermitilis MA-4680 1210176 NP_822483.1 CDS cyp6 NC_003155.4 1616797 1618128 R CYP154D1; cytochrome P450 hydroxylase complement(1616797..1618128) Streptomyces avermitilis MA-4680 1210177 NP_822484.1 CDS SAV_1309 NC_003155.4 1618155 1619378 R PF02771: Acyl-CoA dehydrogenase, N-terminal domain; hypothetical protein complement(1618155..1619378) Streptomyces avermitilis MA-4680 1212902 NP_822485.1 CDS rho NC_003155.4 1619721 1620860 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1619721..1620860 Streptomyces avermitilis MA-4680 1210178 NP_822486.1 CDS dacA NC_003155.4 1620939 1622105 D PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 1620939..1622105 Streptomyces avermitilis MA-4680 1210179 NP_822487.1 CDS SAV_1312 NC_003155.4 1621832 1623214 R hypothetical protein complement(1621832..1623214) Streptomyces avermitilis MA-4680 1212903 NP_822488.1 CDS SAV_1313 NC_003155.4 1623211 1624611 R hypothetical protein complement(1623211..1624611) Streptomyces avermitilis MA-4680 1212904 NP_822489.1 CDS glsA NC_003155.4 1624746 1625687 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1624746..1625687) Streptomyces avermitilis MA-4680 1210180 NP_822490.1 CDS aspA NC_003155.4 1625891 1627303 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(1625891..1627303) Streptomyces avermitilis MA-4680 1210181 NP_822491.1 CDS SAV_1316 NC_003155.4 1627395 1628381 R L-asparaginase II complement(1627395..1628381) Streptomyces avermitilis MA-4680 1212905 NP_822492.1 CDS ansP1 NC_003155.4 1628423 1629883 R L-asparagine permease complement(1628423..1629883) Streptomyces avermitilis MA-4680 1212906 NP_822493.1 CDS SAV_1318 NC_003155.4 1629880 1630647 R GntR-family transcriptional regulator; L-asparagine operon repressor complement(1629880..1630647) Streptomyces avermitilis MA-4680 1212907 NP_822494.1 CDS uppP NC_003155.4 1630747 1631580 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(1630747..1631580) Streptomyces avermitilis MA-4680 1210182 NP_822495.1 CDS ccrB NC_003155.4 1631650 1632024 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1631650..1632024) Streptomyces avermitilis MA-4680 1212908 NP_822496.1 CDS SAV_1321 NC_003155.4 1632021 1632263 R PF02641: Uncharacterized ACR, COG1993; hypothetical protein complement(1632021..1632263) Streptomyces avermitilis MA-4680 1212909 NP_822497.1 CDS ccrB NC_003155.4 1632260 1632736 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1632260..1632736) Streptomyces avermitilis MA-4680 1212910 NP_822498.1 CDS SAV_1323 NC_003155.4 1633159 1633446 R hypothetical protein complement(1633159..1633446) Streptomyces avermitilis MA-4680 1212911 NP_822499.1 CDS SAV_1324 NC_003155.4 1633617 1635185 R arabinogalactan endo-1,4-beta-galactosidase complement(1633617..1635185) Streptomyces avermitilis MA-4680 1212912 NP_822500.1 CDS bga2 NC_003155.4 1635320 1637341 R beta-galactosidase complement(1635320..1637341) Streptomyces avermitilis MA-4680 1210183 NP_822501.1 CDS SAV_1326 NC_003155.4 1637527 1638846 D PF00497: Bacterial extracellular solute-binding proteins, family 3; solute-binding lipoprotein 1637527..1638846 Streptomyces avermitilis MA-4680 1212913 NP_822502.1 CDS SAV_1327 NC_003155.4 1638843 1639766 D ABC transporter permease 1638843..1639766 Streptomyces avermitilis MA-4680 1212914 NP_822503.1 CDS SAV_1328 NC_003155.4 1639763 1640668 D ABC transporter permease 1639763..1640668 Streptomyces avermitilis MA-4680 1212915 NP_822504.1 CDS SAV_1329 NC_003155.4 1640665 1641696 D LacI family transcriptional regulator 1640665..1641696 Streptomyces avermitilis MA-4680 1212916 NP_822505.1 CDS SAV_1330 NC_003155.4 1641935 1642291 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 1641935..1642291 Streptomyces avermitilis MA-4680 1212917 NP_822506.1 CDS SAV_1331 NC_003155.4 1642375 1642764 D MarR family transcriptional regulator 1642375..1642764 Streptomyces avermitilis MA-4680 1212918 NP_822507.1 CDS SAV_1332 NC_003155.4 1642815 1643843 D PF02913: FAD linked oxidases, C-terminal domain; oxidoreductase 1642815..1643843 Streptomyces avermitilis MA-4680 1212919 NP_822508.1 CDS SAV_1333 NC_003155.4 1644029 1644448 R hypothetical protein complement(1644029..1644448) Streptomyces avermitilis MA-4680 1212920 NP_822509.1 CDS prpB6 NC_003155.4 1645153 1646346 D membrane protein; magnesium or manganese-dependent protein phosphatase 1645153..1646346 Streptomyces avermitilis MA-4680 1212921 NP_822510.1 CDS SAV_1335 NC_003155.4 1646423 1646920 R hypothetical protein complement(1646423..1646920) Streptomyces avermitilis MA-4680 1212922 NP_822511.1 CDS SAV_1336 NC_003155.4 1647024 1648022 R rhodanese family protein complement(1647024..1648022) Streptomyces avermitilis MA-4680 1212923 NP_822512.1 CDS SAV_1337 NC_003155.4 1648366 1649301 D ABC transporter substrate-binding protein 1648366..1649301 Streptomyces avermitilis MA-4680 1212924 NP_822513.1 CDS SAV_1338 NC_003155.4 1649428 1650465 D ABC transporter substrate-binding protein 1649428..1650465 Streptomyces avermitilis MA-4680 1212925 NP_822514.1 CDS SAV_1339 NC_003155.4 1650462 1651235 D ABC transporter permease 1650462..1651235 Streptomyces avermitilis MA-4680 1212926 NP_822515.1 CDS SAV_1340 NC_003155.4 1651199 1652026 D ABC transporter ATP-binding protein 1651199..1652026 Streptomyces avermitilis MA-4680 1212927 NP_822516.1 CDS SAV_1341 NC_003155.4 1652023 1653147 D PF01636: Phosphotransferase enzyme family; hypothetical protein 1652023..1653147 Streptomyces avermitilis MA-4680 1212928 NP_822517.1 CDS SAV_1342 NC_003155.4 1653663 1655132 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 1653663..1655132 Streptomyces avermitilis MA-4680 1212929 NP_822518.1 CDS SAV_1343 NC_003155.4 1655307 1656512 R PF00923: Transaldolase; hypothetical protein complement(1655307..1656512) Streptomyces avermitilis MA-4680 1212930 NP_822519.1 CDS SAV_1344 NC_003155.4 1656575 1657990 R PF01593: Flavin containing amine oxidoreductase; dehydrogenase complement(1656575..1657990) Streptomyces avermitilis MA-4680 1212931 NP_822520.1 CDS SAV_1345 NC_003155.4 1657983 1659725 R hypothetical protein complement(1657983..1659725) Streptomyces avermitilis MA-4680 1212932 NP_822521.1 CDS SAV_1346 NC_003155.4 1659744 1661201 R acid:CoA ligase complement(1659744..1661201) Streptomyces avermitilis MA-4680 1212933 NP_822522.1 CDS gcdH2 NC_003155.4 1661612 1662823 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; glutaryl-CoA dehydrogenase complement(1661612..1662823) Streptomyces avermitilis MA-4680 1210184 NP_822523.1 CDS fadC7 NC_003155.4 1662820 1663776 R PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase complement(1662820..1663776) Streptomyces avermitilis MA-4680 1210185 NP_822524.1 CDS adc NC_003155.4 1663815 1664570 R converts acetoacetate to acetone and carbon dioxide; acetoacetate decarboxylase complement(1663815..1664570) Streptomyces avermitilis MA-4680 1210186 NP_822525.1 CDS echA5 NC_003155.4 1664591 1665361 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1664591..1665361) Streptomyces avermitilis MA-4680 1210187 NP_822526.1 CDS SAV_1351 NC_003155.4 1665388 1666557 R fatty acid-CoA racemase complement(1665388..1666557) Streptomyces avermitilis MA-4680 1212934 NP_822527.1 CDS SAV_1352 NC_003155.4 1666726 1667637 R LysR family transcriptional regulator complement(1666726..1667637) Streptomyces avermitilis MA-4680 1212935 NP_822528.1 CDS SAV_1353 NC_003155.4 1667828 1669231 R PF00754: F5/8 type C domain; protein complement(1667828..1669231) Streptomyces avermitilis MA-4680 1212936 NP_822529.1 CDS SAV_1354 NC_003155.4 1669689 1671080 R amino acid permease complement(1669689..1671080) Streptomyces avermitilis MA-4680 1212937 NP_822530.1 CDS SAV_1355 NC_003155.4 1671135 1672004 R PF00795: Carbon-nitrogen hydrolase; hydrolase complement(1671135..1672004) Streptomyces avermitilis MA-4680 1212938 NP_822531.1 CDS SAV_1356 NC_003155.4 1672099 1672869 D GntR family transcriptional regulator 1672099..1672869 Streptomyces avermitilis MA-4680 1212939 NP_822532.1 CDS adhA2 NC_003155.4 1673000 1674022 D PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase 1673000..1674022 Streptomyces avermitilis MA-4680 1212940 NP_822533.1 CDS SAV_1358 NC_003155.4 1674152 1674853 R hypothetical protein complement(1674152..1674853) Streptomyces avermitilis MA-4680 1212941 NP_822534.1 CDS SAV_1359 NC_003155.4 1674937 1675689 D TetR family transcriptional regulator 1674937..1675689 Streptomyces avermitilis MA-4680 1212942 NP_822535.1 CDS SAV_1360 NC_003155.4 1675968 1676225 D hypothetical protein 1675968..1676225 Streptomyces avermitilis MA-4680 1212943 NP_822536.1 CDS SAV_1361 NC_003155.4 1676443 1677468 D hypothetical protein 1676443..1677468 Streptomyces avermitilis MA-4680 1212944 NP_822537.1 CDS SAV_1362 NC_003155.4 1677776 1678258 R transcriptional regulator complement(1677776..1678258) Streptomyces avermitilis MA-4680 1212945 NP_822538.1 CDS SAV_1363 NC_003155.4 1678404 1679132 D PF01113: Dihydrodipicolinate reductase, N-terminus; protein 1678404..1679132 Streptomyces avermitilis MA-4680 1212946 NP_822539.1 CDS SAV_1364 NC_003155.4 1679068 1680150 D hypothetical protein 1679068..1680150 Streptomyces avermitilis MA-4680 1212947 NP_822540.1 CDS SAV_1365 NC_003155.4 1680147 1680689 R hypothetical protein complement(1680147..1680689) Streptomyces avermitilis MA-4680 1212948 NP_822541.1 CDS SAV_1366 NC_003155.4 1680974 1683826 D PF01447: Thermolysin metallopeptidase, catalytic domain; metalloprotease 1680974..1683826 Streptomyces avermitilis MA-4680 1212949 NP_822542.1 CDS SAV_1367 NC_003155.4 1684007 1684810 R PF00106: short chain dehydrogenase; dehydrogenase complement(1684007..1684810) Streptomyces avermitilis MA-4680 1212950 NP_822543.1 CDS SAV_1368 NC_003155.4 1684807 1685763 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(1684807..1685763) Streptomyces avermitilis MA-4680 1212951 NP_822544.1 CDS SAV_1369 NC_003155.4 1686236 1686775 D PF04341: Protein of unknown function, DUF485; hypothetical protein 1686236..1686775 Streptomyces avermitilis MA-4680 1212952 NP_822545.1 CDS SAV_1370 NC_003155.4 1686772 1688388 D PF00474: Sodium:solute symporter family; transmembrane transport protein 1686772..1688388 Streptomyces avermitilis MA-4680 1212953 NP_822546.1 CDS SAV_1371 NC_003155.4 1688543 1689622 D AraC family transcription regulator 1688543..1689622 Streptomyces avermitilis MA-4680 1212954 NP_822547.1 CDS ilvB2 NC_003155.4 1689619 1691415 D acetolactate synthase 1689619..1691415 Streptomyces avermitilis MA-4680 1210189 NP_822548.1 CDS SAV_1373 NC_003155.4 1691387 1692040 D hypothetical protein 1691387..1692040 Streptomyces avermitilis MA-4680 1212955 NP_822549.1 CDS fabH5 NC_003155.4 1692037 1693056 D 3-oxoacyl-ACP synthase III 1692037..1693056 Streptomyces avermitilis MA-4680 1210190 NP_822550.1 CDS hisC3 NC_003155.4 1693060 1694154 D EC:2.6.1.9; histidinol-phosphate aminotransferase 1693060..1694154 Streptomyces avermitilis MA-4680 1210191 NP_822551.1 CDS SAV_1376 NC_003155.4 1694414 1695211 R PF07398: Protein of unknown function (DUF1503); hypothetical protein complement(1694414..1695211) Streptomyces avermitilis MA-4680 1212956 NP_822552.1 CDS SAV_1377 NC_003155.4 1695242 1695415 R hypothetical protein complement(1695242..1695415) Streptomyces avermitilis MA-4680 1212957 NP_822553.1 CDS SAV_1378 NC_003155.4 1695483 1696991 R PF07690: Major Facilitator Superfamily; membrane transport protein complement(1695483..1696991) Streptomyces avermitilis MA-4680 1212958 NP_822554.1 CDS SAV_1379 NC_003155.4 1697123 1697560 D MarR family transcriptional regulator 1697123..1697560 Streptomyces avermitilis MA-4680 1212959 NP_822555.1 CDS fabG NC_003155.4 1697945 1698727 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1697945..1698727) Streptomyces avermitilis MA-4680 1212960 NP_822556.1 CDS fadE15 NC_003155.4 1698729 1699994 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(1698729..1699994) Streptomyces avermitilis MA-4680 1210192 NP_822557.1 CDS SAV_1382 NC_003155.4 1700439 1701167 R TetR family transcriptional regulator complement(1700439..1701167) Streptomyces avermitilis MA-4680 1212961 NP_822558.1 CDS SAV_1383 NC_003155.4 1701234 1701881 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(1701234..1701881) Streptomyces avermitilis MA-4680 1212962 NP_822559.1 CDS fadA5 NC_003155.4 1702011 1703210 R atoB: acetyl-CoA C-acetyltransferase, PF00108: Thiolase, N-terminal domain; 3-ketoacyl-CoA thiolase complement(1702011..1703210) Streptomyces avermitilis MA-4680 1210193 NP_822560.1 CDS SAV_1385 NC_003155.4 1703980 1705092 R hypothetical protein complement(1703980..1705092) Streptomyces avermitilis MA-4680 1212963 NP_822561.1 CDS glcD1 NC_003155.4 1706772 1708142 R similar to glycolate oxidase: PF01565: FAD binding domain; (S)-2-hydroxy-acid oxidase complement(1706772..1708142) Streptomyces avermitilis MA-4680 1212964 NP_822562.1 CDS SAV_1387 NC_003155.4 1708139 1708849 R GntR family transcriptional regulator complement(1708139..1708849) Streptomyces avermitilis MA-4680 1212965 NP_822563.1 CDS SAV_1388 NC_003155.4 1708859 1709566 D PF00857: Isochorismatase family; isochorismatase 1708859..1709566 Streptomyces avermitilis MA-4680 1212966 NP_822564.1 CDS SAV_1389 NC_003155.4 1709632 1710909 D hypothetical protein 1709632..1710909 Streptomyces avermitilis MA-4680 1212967 NP_822565.1 CDS SAV_1390 NC_003155.4 1711093 1712622 D PF00743: Flavin-binding monooxygenase-like; aromatic-ring hydroxylase 1711093..1712622 Streptomyces avermitilis MA-4680 1212968 NP_822566.1 CDS prpJ5 NC_003155.4 1714511 1717072 R PF00989: PAS domain, PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(1714511..1717072) Streptomyces avermitilis MA-4680 1212969 NP_822567.1 CDS SAV_1392 NC_003155.4 1717280 1719070 R PF01590: GAF domain; transcriptional regulator complement(1717280..1719070) Streptomyces avermitilis MA-4680 1212970 NP_822568.1 CDS adhA3 NC_003155.4 1719247 1720272 D PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase 1719247..1720272 Streptomyces avermitilis MA-4680 1212971 NP_822569.1 CDS SAV_1394 NC_003155.4 1720293 1721894 D ABC transporter substrate-binding protein 1720293..1721894 Streptomyces avermitilis MA-4680 1212972 NP_822570.1 CDS SAV_1395 NC_003155.4 1721916 1722854 D ABC transporter permease 1721916..1722854 Streptomyces avermitilis MA-4680 1212973 NP_822571.1 CDS SAV_1396 NC_003155.4 1722851 1723696 D ABC transporter permease 1722851..1723696 Streptomyces avermitilis MA-4680 1212974 NP_822572.1 CDS SAV_1397 NC_003155.4 1723693 1724781 D sugar ABC transporter ATP-binding protein 1723693..1724781 Streptomyces avermitilis MA-4680 1212975 NP_822573.1 CDS SAV_1398 NC_003155.4 1724783 1725862 D sugar ABC transporter ATP-binding protein 1724783..1725862 Streptomyces avermitilis MA-4680 1212976 NP_822574.1 CDS SAV_1399 NC_003155.4 1726146 1728530 D hypothetical protein 1726146..1728530 Streptomyces avermitilis MA-4680 1212977 NP_822575.1 CDS SAV_1400 NC_003155.4 1728527 1729672 D hypothetical protein 1728527..1729672 Streptomyces avermitilis MA-4680 1212978 NP_822576.1 CDS SAV_1401 NC_003155.4 1729690 1730592 D hypothetical protein 1729690..1730592 Streptomyces avermitilis MA-4680 1212979 NP_822577.1 CDS SAV_1402 NC_003155.4 1730649 1731056 D hypothetical protein 1730649..1731056 Streptomyces avermitilis MA-4680 1212980 NP_822578.1 CDS SAV_1403 NC_003155.4 1731053 1731502 D hypothetical protein 1731053..1731502 Streptomyces avermitilis MA-4680 1212981 NP_822579.1 CDS SAV_1404 NC_003155.4 1731705 1732691 R PF00248: Aldo/keto reductase family; oxidoreductase complement(1731705..1732691) Streptomyces avermitilis MA-4680 1212982 NP_822580.1 CDS SAV_1405 NC_003155.4 1732688 1733521 R PF04909: Amidohydrolase; amidohydrolase complement(1732688..1733521) Streptomyces avermitilis MA-4680 1212983 NP_822581.1 CDS SAV_1406 NC_003155.4 1734129 1734905 D GntR family transcriptional regulator 1734129..1734905 Streptomyces avermitilis MA-4680 1212984 NP_822582.1 CDS SAV_1407 NC_003155.4 1734993 1738382 D PF00041: Fibronectin type III domain; hypothetical protein 1734993..1738382 Streptomyces avermitilis MA-4680 1212985 NP_822583.1 CDS SAV_1408 NC_003155.4 1738439 1739536 D racemase 1738439..1739536 Streptomyces avermitilis MA-4680 1212986 NP_822584.1 CDS SAV_1409 NC_003155.4 1739569 1740954 D solute-binding protein 1739569..1740954 Streptomyces avermitilis MA-4680 1212987 NP_822585.1 CDS SAV_1410 NC_003155.4 1740951 1741883 D ABC transporter permease 1740951..1741883 Streptomyces avermitilis MA-4680 1212988 NP_822586.1 CDS SAV_1411 NC_003155.4 1741880 1742794 D ABC transporter permease 1741880..1742794 Streptomyces avermitilis MA-4680 1212989 NP_822587.1 CDS SAV_1412 NC_003155.4 1742840 1744534 D hypothetical protein 1742840..1744534 Streptomyces avermitilis MA-4680 1212990 NP_822588.1 CDS glkA2 NC_003155.4 1744531 1745499 D glucokinase 1744531..1745499 Streptomyces avermitilis MA-4680 1210194 NP_822589.1 CDS SAV_1414 NC_003155.4 1746233 1747186 R hypothetical protein complement(1746233..1747186) Streptomyces avermitilis MA-4680 1212991 NP_822590.1 CDS SAV_1415 NC_003155.4 1747548 1747778 R protease complement(1747548..1747778) Streptomyces avermitilis MA-4680 1212992 NP_822591.1 CDS SAV_1416 NC_003155.4 1748025 1748549 D hypothetical protein 1748025..1748549 Streptomyces avermitilis MA-4680 1212993 NP_822592.1 CDS SAV_1417 NC_003155.4 1748916 1749656 D hypothetical protein 1748916..1749656 Streptomyces avermitilis MA-4680 1212994 NP_822593.1 CDS SAV_1418 NC_003155.4 1750041 1751474 D PF00083: Sugar (and other) transporter; transporter 1750041..1751474 Streptomyces avermitilis MA-4680 1212995 NP_822594.1 CDS SAV_1419 NC_003155.4 1751539 1753476 R PF01590: GAF domain; hypothetical protein complement(1751539..1753476) Streptomyces avermitilis MA-4680 1212996 NP_822595.1 CDS bdhA NC_003155.4 1753546 1754346 R PF00106: short chain dehydrogenase; 3-hydroxybutyrate dehydrogenase complement(1753546..1754346) Streptomyces avermitilis MA-4680 1212997 NP_822596.1 CDS SAV_1421 NC_003155.4 1754407 1754880 R MutT/NUDIX-family protein complement(1754407..1754880) Streptomyces avermitilis MA-4680 1212998 NP_822597.1 CDS SAV_1422 NC_003155.4 1754929 1756548 R polyprenol-phosphate-mannosyl transferase complement(1754929..1756548) Streptomyces avermitilis MA-4680 1212999 NP_822598.1 CDS SAV_1423 NC_003155.4 1756680 1757813 D PF04932: O-Antigen Polymerase; hypothetical protein 1756680..1757813 Streptomyces avermitilis MA-4680 1213000 NP_822599.1 CDS SAV_1424 NC_003155.4 1757862 1758407 R hypothetical protein complement(1757862..1758407) Streptomyces avermitilis MA-4680 1213001 NP_822600.1 CDS murI NC_003155.4 1758546 1759331 R glutamate racemase complement(1758546..1759331) Streptomyces avermitilis MA-4680 1210195 NP_822601.1 CDS SAV_1426 NC_003155.4 1759390 1760565 D PF00535: Glycosyl transferase; glycosyl transferase 1759390..1760565 Streptomyces avermitilis MA-4680 1213002 NP_822602.1 CDS terA NC_003155.4 1760590 1761915 R PF02342: Bacterial stress protein; tellurium resistance protein complement(1760590..1761915) Streptomyces avermitilis MA-4680 1213003 NP_822603.1 CDS SAV_1428 NC_003155.4 1762252 1762692 D hypothetical protein 1762252..1762692 Streptomyces avermitilis MA-4680 1213004 NP_822604.1 CDS SAV_1429 NC_003155.4 1762737 1763561 D PF03473: MOSC domain, PF03476: MOSC N-terminal beta barrel domain; hypothetical protein 1762737..1763561 Streptomyces avermitilis MA-4680 1213005 NP_822605.1 CDS SAV_1430 NC_003155.4 1763811 1764416 D hypothetical protein 1763811..1764416 Streptomyces avermitilis MA-4680 1213006 NP_822606.1 CDS spoVK NC_003155.4 1764524 1766962 D ATPases of the AAA+ class, PF00004: ATPase family associated with various cellular activities (AAA); sporulation protein K-like protein 1764524..1766962 Streptomyces avermitilis MA-4680 1210196 NP_822607.1 CDS SAV_1432 NC_003155.4 1766932 1769265 R hypothetical protein complement(1766932..1769265) Streptomyces avermitilis MA-4680 1213007 NP_822608.1 CDS SAV_1433 NC_003155.4 1769668 1770498 D DeoR family transcriptional regulator 1769668..1770498 Streptomyces avermitilis MA-4680 1213008 NP_822609.1 CDS SAV_1434 NC_003155.4 1770611 1771090 D PF03364: Streptomyces cyclase/dehydrase; hypothetical protein 1770611..1771090 Streptomyces avermitilis MA-4680 1213009 NP_822610.1 CDS cysK1 NC_003155.4 1771143 1772267 R cysteine synthase/cystathionine beta-synthase family protein complement(1771143..1772267) Streptomyces avermitilis MA-4680 1213010 NP_822611.1 CDS SAV_1436 NC_003155.4 1772634 1772957 D hypothetical protein 1772634..1772957 Streptomyces avermitilis MA-4680 1213011 NP_822612.1 CDS SAV_1437 NC_003155.4 1773206 1773721 D regulatory protein 1773206..1773721 Streptomyces avermitilis MA-4680 1213012 NP_822613.1 CDS SAV_1438 NC_003155.4 1773932 1774243 R hypothetical protein complement(1773932..1774243) Streptomyces avermitilis MA-4680 1213013 NP_822614.1 CDS SAV_1439 NC_003155.4 1774392 1774967 D TetR family transcriptional regulator 1774392..1774967 Streptomyces avermitilis MA-4680 1213014 NP_822615.1 CDS SAV_1440 NC_003155.4 1775061 1775645 D hypothetical protein 1775061..1775645 Streptomyces avermitilis MA-4680 1213015 NP_822616.1 CDS SAV_1441 NC_003155.4 1775639 1776550 D phosphotriesterase-family protein 1775639..1776550 Streptomyces avermitilis MA-4680 1213016 NP_822617.1 CDS SAV_1442 NC_003155.4 1776636 1777880 R transcriptional regulator complement(1776636..1777880) Streptomyces avermitilis MA-4680 1213017 NP_822618.1 CDS SAV_1443 NC_003155.4 1778014 1778682 R alkylation damage repair; DNA repair protein complement(1778014..1778682) Streptomyces avermitilis MA-4680 1213018 NP_822619.1 CDS rsmC NC_003155.4 1778763 1779905 D ribosomal RNA small subunit methyltransferase 1778763..1779905 Streptomyces avermitilis MA-4680 1213019 NP_822620.1 CDS gatY NC_003155.4 1779895 1780800 R tagatose-bisphosphate aldolase complement(1779895..1780800) Streptomyces avermitilis MA-4680 1210197 NP_822621.1 CDS SAV_1446 NC_003155.4 1780834 1781784 R PF01380: SIS domain; putave phosphosugar isomerase complement(1780834..1781784) Streptomyces avermitilis MA-4680 1213020 NP_822622.1 CDS SAV_1447 NC_003155.4 1781851 1782630 D DeoR family transcriptional regulator 1781851..1782630 Streptomyces avermitilis MA-4680 1213021 NP_822623.1 CDS SAV_1448 NC_003155.4 1782944 1783813 D PF07728: ATPase family associated with various cellular activities (AAA); MoxR-like ATPase 1782944..1783813 Streptomyces avermitilis MA-4680 1213022 NP_822624.1 CDS SAV_1449 NC_003155.4 1783810 1785183 D PF05762: VWA domain containing CoxE-like protein; hypothetical protein 1783810..1785183 Streptomyces avermitilis MA-4680 1213023 NP_822625.1 CDS SAV_1450 NC_003155.4 1785294 1787336 D alpha-glucuronidase 1785294..1787336 Streptomyces avermitilis MA-4680 1210198 NP_822626.1 CDS bga3 NC_003155.4 1787385 1789421 R beta-galactosidase complement(1787385..1789421) Streptomyces avermitilis MA-4680 1210199 NP_822627.1 CDS SAV_1452 NC_003155.4 1789418 1790179 R hypothetical protein complement(1789418..1790179) Streptomyces avermitilis MA-4680 1213024 NP_822628.1 CDS xynB1 NC_003155.4 1790131 1791654 R xylan 1,4-beta-xylosidase complement(1790131..1791654) Streptomyces avermitilis MA-4680 1210200 NP_822629.1 CDS SAV_1454 NC_003155.4 1791651 1793300 R ABC transporter substrate-binding protein complement(1791651..1793300) Streptomyces avermitilis MA-4680 1213025 NP_822630.1 CDS SAV_1455 NC_003155.4 1793336 1794262 R PF00528: Binding-protein-dependent transport system inner membrane component; ABC transporter permease complement(1793336..1794262) Streptomyces avermitilis MA-4680 1213026 NP_822631.1 CDS lplB NC_003155.4 1794256 1795254 R multiple sugar ABC transport permease complement(1794256..1795254) Streptomyces avermitilis MA-4680 1210201 NP_822632.1 CDS axe2 NC_003155.4 1795541 1796542 D PF05448: Acetyl xylan esterase (AXE1); acetyl xylan esterase 1795541..1796542 Streptomyces avermitilis MA-4680 1213027 NP_822633.1 CDS SAV_1458 NC_003155.4 1796587 1797810 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(1796587..1797810) Streptomyces avermitilis MA-4680 1213028 NP_822634.1 CDS SAV_1459 NC_003155.4 1797842 1800043 R glycogen debranching enzyme complement(1797842..1800043) Streptomyces avermitilis MA-4680 1213029 NP_822635.1 CDS SAV_1460 NC_003155.4 1800284 1803319 D ATP/GTP-binding protein 1800284..1803319 Streptomyces avermitilis MA-4680 1213030 NP_822636.1 CDS SAV_1461 NC_003155.4 1803393 1804592 D PF07690: Major Facilitator Superfamily; integral membrane transport protein 1803393..1804592 Streptomyces avermitilis MA-4680 1213031 NP_822637.1 CDS SAV_1463 NC_003155.4 1804744 1805259 R MarR family transcriptional regulator complement(1804744..1805259) Streptomyces avermitilis MA-4680 1213032 NP_822638.1 CDS SAV_1462 NC_003155.4 1805240 1806721 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 1805240..1806721 Streptomyces avermitilis MA-4680 1213033 NP_822639.1 CDS SAV_1464 NC_003155.4 1806823 1807488 R two-component system response regulator complement(1806823..1807488) Streptomyces avermitilis MA-4680 1213034 NP_822640.1 CDS SAV_1465 NC_003155.4 1807485 1808822 R two-component system sensor kinase complement(1807485..1808822) Streptomyces avermitilis MA-4680 1213035 NP_822641.1 CDS SAV_1466 NC_003155.4 1808928 1809578 R TetR family transcriptional regulator complement(1808928..1809578) Streptomyces avermitilis MA-4680 1213036 NP_822642.1 CDS SAV_1467 NC_003155.4 1809764 1810807 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 1809764..1810807 Streptomyces avermitilis MA-4680 1213037 NP_822643.1 CDS SAV_1468 NC_003155.4 1810861 1811595 R TetR family transcriptional regulator complement(1810861..1811595) Streptomyces avermitilis MA-4680 1213038 NP_822644.1 CDS SAV_1469 NC_003155.4 1811682 1812233 D PF04075: Domain of unknown function (DUF385); hypothetical protein 1811682..1812233 Streptomyces avermitilis MA-4680 1213039 NP_822645.1 CDS SAV_1470 NC_003155.4 1812317 1813522 R hydrogenase complement(1812317..1813522) Streptomyces avermitilis MA-4680 1213040 NP_822646.1 CDS SAV_1471 NC_003155.4 1813707 1815062 D PF01546: Peptidase family M20/M25/M40; hypothetical protein 1813707..1815062 Streptomyces avermitilis MA-4680 1213041 NP_822647.1 CDS SAV_1472 NC_003155.4 1815103 1815852 D PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase-like protein 1815103..1815852 Streptomyces avermitilis MA-4680 1213042 NP_822648.1 CDS SAV_1473 NC_003155.4 1815974 1817014 R ATP/GTP-binding protein complement(1815974..1817014) Streptomyces avermitilis MA-4680 1213043 NP_822649.1 CDS SAV_1474 NC_003155.4 1817167 1817361 R protein complement(1817167..1817361) Streptomyces avermitilis MA-4680 1213044 NP_822650.1 CDS agaB2 NC_003155.4 1817779 1819827 D alpha-galactosidase 1817779..1819827 Streptomyces avermitilis MA-4680 1210202 NP_822651.1 CDS SAV_1476 NC_003155.4 1819858 1820817 R transcriptional regulator complement(1819858..1820817) Streptomyces avermitilis MA-4680 1213045 NP_822652.1 CDS SAV_1477 NC_003155.4 1821069 1822106 D LacI family transcriptional regulator 1821069..1822106 Streptomyces avermitilis MA-4680 1213046 NP_822653.1 CDS SAV_1478 NC_003155.4 1822322 1823641 R hypothetical protein complement(1822322..1823641) Streptomyces avermitilis MA-4680 1213047 NP_822654.1 CDS SAV_1479 NC_003155.4 1823751 1824662 D PF03372: Endonuclease/Exonuclease/phosphatase family; hypothetical protein 1823751..1824662 Streptomyces avermitilis MA-4680 1213048 NP_822655.1 CDS fixB NC_003155.4 1824783 1825745 R electron transfer flavoprotein, alpha subunit complement(1824783..1825745) Streptomyces avermitilis MA-4680 1210203 NP_822656.1 CDS fixA NC_003155.4 1825800 1826594 R electron transfer flavoprotein, beta subunit complement(1825800..1826594) Streptomyces avermitilis MA-4680 1210204 NP_822657.1 CDS thiX1 NC_003155.4 1826786 1827292 R flavin-dependent reductase complement(1826786..1827292) Streptomyces avermitilis MA-4680 1210205 NP_822658.1 CDS trxA4 NC_003155.4 1827499 1827912 R thioredoxin complement(1827499..1827912) Streptomyces avermitilis MA-4680 1210206 NP_822659.1 CDS SAV_1484 NC_003155.4 1828015 1828431 D hypothetical protein 1828015..1828431 Streptomyces avermitilis MA-4680 1213049 NP_822660.1 CDS plsC1 NC_003155.4 1828617 1829345 D 1-acylglycerol-3-phosphate O-acyltransferase 1828617..1829345 Streptomyces avermitilis MA-4680 1210207 NP_822661.1 CDS SAV_1486 NC_003155.4 1829350 1830042 R PF03483: B3/4 domain; hypothetical protein complement(1829350..1830042) Streptomyces avermitilis MA-4680 1213050 NP_822662.1 CDS SAV_1487 NC_003155.4 1830057 1830656 R hypothetical protein complement(1830057..1830656) Streptomyces avermitilis MA-4680 1213051 NP_822663.1 CDS ltaA NC_003155.4 1830717 1831787 R L-threonine aldolase complement(1830717..1831787) Streptomyces avermitilis MA-4680 1210208 NP_822664.1 CDS SAV_1489 NC_003155.4 1831784 1832530 R PF00106: short chain dehydrogenase; dehydrogenase complement(1831784..1832530) Streptomyces avermitilis MA-4680 1213052 NP_822665.1 CDS SAV_1490 NC_003155.4 1832569 1833966 R hypothetical protein complement(1832569..1833966) Streptomyces avermitilis MA-4680 1213053 NP_822666.1 CDS SAV_1491 NC_003155.4 1834048 1834539 R hypothetical protein complement(1834048..1834539) Streptomyces avermitilis MA-4680 1213054 NP_822667.1 CDS glpQ5 NC_003155.4 1834659 1835342 D glycerophosphoryl diester phosphodiesterase 1834659..1835342 Streptomyces avermitilis MA-4680 1210209 NP_822668.1 CDS SAV_1493 NC_003155.4 1835346 1835885 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(1835346..1835885) Streptomyces avermitilis MA-4680 1213055 NP_822669.1 CDS SAV_1494 NC_003155.4 1835957 1836349 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 1835957..1836349 Streptomyces avermitilis MA-4680 1213056 NP_822670.1 CDS SAV_1495 NC_003155.4 1836411 1837175 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hydroxylase 1836411..1837175 Streptomyces avermitilis MA-4680 1213057 NP_822671.1 CDS SAV_1496 NC_003155.4 1837172 1837690 R PF00190: Cupin; hypothetical protein complement(1837172..1837690) Streptomyces avermitilis MA-4680 1213058 NP_822672.1 CDS SAV_1497 NC_003155.4 1837808 1838404 R MarR family transcriptional regulator complement(1837808..1838404) Streptomyces avermitilis MA-4680 1213059 NP_822673.1 CDS SAV_1498 NC_003155.4 1838401 1840062 R integral membrane protein complement(1838401..1840062) Streptomyces avermitilis MA-4680 1213060 NP_822674.1 CDS SAV_1499 NC_003155.4 1840223 1840771 D integral membrane protein 1840223..1840771 Streptomyces avermitilis MA-4680 1213061 NP_822675.1 CDS SAV_1500 NC_003155.4 1840948 1841883 D PF01435: Peptidase family M48; integral membrane protein 1840948..1841883 Streptomyces avermitilis MA-4680 1213062 NP_822676.1 CDS SAV_1501 NC_003155.4 1841987 1842670 D PF01569: PAP2 superfamily; hypothetical protein 1841987..1842670 Streptomyces avermitilis MA-4680 1213063 NP_822677.1 CDS SAV_1502 NC_003155.4 1842744 1843442 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 1842744..1843442 Streptomyces avermitilis MA-4680 1213064 NP_822678.1 CDS SAV_1503 NC_003155.4 1843601 1844320 D TetR family transcriptional regulator 1843601..1844320 Streptomyces avermitilis MA-4680 1213065 NP_822679.1 CDS SAV_1504 NC_003155.4 1844308 1845810 R protein complement(1844308..1845810) Streptomyces avermitilis MA-4680 1213066 NP_822680.1 CDS SAV_1505 NC_003155.4 1845876 1846595 D PF03713: Domain of unknown function (DUF305); lipoprotein 1845876..1846595 Streptomyces avermitilis MA-4680 1213067 NP_822681.1 CDS SAV_1506 NC_003155.4 1846605 1847069 R hypothetical protein complement(1846605..1847069) Streptomyces avermitilis MA-4680 1213068 NP_822682.1 CDS fprB NC_003155.4 1847273 1848619 D NADPH-ferredoxin reductase 1847273..1848619 Streptomyces avermitilis MA-4680 1210210 NP_822683.1 CDS pbuX1 NC_003155.4 1848745 1850100 D xanthine/uracil permease 1848745..1850100 Streptomyces avermitilis MA-4680 1210211 NP_822684.1 CDS SAV_1509 NC_003155.4 1850086 1850445 R transcription regulator ArsR complement(1850086..1850445) Streptomyces avermitilis MA-4680 1213069 NP_822685.1 CDS SAV_1510 NC_003155.4 1850562 1851641 D PF00724: NADH:flavin oxidoreductase / NADH oxidase family; oxidoreductase 1850562..1851641 Streptomyces avermitilis MA-4680 1213070 NP_822686.1 CDS SAV_1511 NC_003155.4 1851838 1852749 R sugar kinase complement(1851838..1852749) Streptomyces avermitilis MA-4680 1213071 NP_822687.1 CDS SAV_1512 NC_003155.4 1852830 1853459 R hypothetical protein complement(1852830..1853459) Streptomyces avermitilis MA-4680 1213072 NP_822688.1 CDS SAV_1513 NC_003155.4 1853697 1854839 D PF02012: BNR/Asp-box repeat; hypothetical protein 1853697..1854839 Streptomyces avermitilis MA-4680 1213073 NP_822689.1 CDS malS1 NC_003155.4 1855017 1856780 D malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1855017..1856780 Streptomyces avermitilis MA-4680 1210212 NP_822690.1 CDS SAV_1515 NC_003155.4 1856893 1857978 D PF03547: Auxin Efflux Carrier; transport integral membrane protein 1856893..1857978 Streptomyces avermitilis MA-4680 1213074 NP_822691.1 CDS SAV_1516 NC_003155.4 1858078 1859835 D PF05976: Bacterial membrane protein of unknown function (DUF893); integral membrane protein 1858078..1859835 Streptomyces avermitilis MA-4680 1213075 NP_822692.1 CDS SAV_1517 NC_003155.4 1859956 1860894 D LysR family transcriptional regulator 1859956..1860894 Streptomyces avermitilis MA-4680 1213076 NP_822693.1 CDS SAV_1518 NC_003155.4 1860949 1861248 R hypothetical protein complement(1860949..1861248) Streptomyces avermitilis MA-4680 1213077 NP_822694.1 CDS SAV_1519 NC_003155.4 1861569 1862282 D PF00106: short chain dehydrogenase; dehydrogenase 1861569..1862282 Streptomyces avermitilis MA-4680 1213078 NP_822695.1 CDS SAV_1520 NC_003155.4 1862701 1863681 D catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1862701..1863681 Streptomyces avermitilis MA-4680 1213079 NP_822696.1 CDS SAV_1521 NC_003155.4 1863707 1864315 D PF07336: Protein of unknown function (DUF1470); hypothetical protein 1863707..1864315 Streptomyces avermitilis MA-4680 1213080 NP_822697.1 CDS SAV_1522 NC_003155.4 1864635 1865171 D epoxide hydrolase 1864635..1865171 Streptomyces avermitilis MA-4680 1213081 NP_822698.1 CDS SAV_1523 NC_003155.4 1865337 1865780 D lyase 1865337..1865780 Streptomyces avermitilis MA-4680 1213082 NP_822699.1 CDS SAV_1524 NC_003155.4 1865838 1866458 R TetR family transcriptional regulator complement(1865838..1866458) Streptomyces avermitilis MA-4680 1213083 NP_822700.1 CDS SAV_1525 NC_003155.4 1866759 1867412 R muconolactone delta-isomerase complement(1866759..1867412) Streptomyces avermitilis MA-4680 1213084 NP_822701.1 CDS SAV_1526 NC_003155.4 1867505 1868419 D LysR family transcriptional regulator 1867505..1868419 Streptomyces avermitilis MA-4680 1213085 NP_822702.1 CDS ung1 NC_003155.4 1869096 1869773 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1869096..1869773) Streptomyces avermitilis MA-4680 1210213 NP_822703.1 CDS SAV_1528 NC_003155.4 1870024 1871082 D PF01869: BadF/BadG/BcrA/BcrD ATPase family; hypothetical protein 1870024..1871082 Streptomyces avermitilis MA-4680 1213086 NP_822704.1 CDS SAV_1529 NC_003155.4 1871275 1872198 D hypothetical protein 1871275..1872198 Streptomyces avermitilis MA-4680 1213087 NP_822705.1 CDS SAV_1530 NC_003155.4 1872321 1873361 R protein complement(1872321..1873361) Streptomyces avermitilis MA-4680 1213088 NP_822706.2 CDS nos NC_003155.4 1873463 1875013 R nitric oxide synthase complement(1873463..1875013) Streptomyces avermitilis MA-4680 1213089 NP_822707.1 CDS SAV_7579 NC_003155.4 1875451 1877058 R hypothetical protein complement(1875451..1877058) Streptomyces avermitilis MA-4680 1213090 NP_822708.1 CDS SAV_1532 NC_003155.4 1877224 1877448 D hypothetical protein 1877224..1877448 Streptomyces avermitilis MA-4680 1213091 NP_822709.1 CDS SAV_1533 NC_003155.4 1877473 1877823 R PF03861: ANTAR domain; hypothetical protein complement(1877473..1877823) Streptomyces avermitilis MA-4680 1213092 NP_822710.1 CDS SAV_1534 NC_003155.4 1878051 1878527 D transcription regulator AsnC 1878051..1878527 Streptomyces avermitilis MA-4680 1213093 NP_822711.1 CDS SAV_1535 NC_003155.4 1878548 1879243 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 1878548..1879243 Streptomyces avermitilis MA-4680 1213094 NP_822712.1 CDS SAV_1536 NC_003155.4 1879347 1880507 R PF02625: XdhC and CoxI family; hypothetical protein complement(1879347..1880507) Streptomyces avermitilis MA-4680 1213095 NP_822713.1 CDS SAV_1538 NC_003155.4 1880483 1882642 R frameshift; oxidoreductase complement(1880483..1882642) Streptomyces avermitilis MA-4680 1213096 NP_822714.1 CDS SAV_1537 NC_003155.4 1880500 1881987 R frameshift, PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; oxidoreductase complement(1880500..1881987) Streptomyces avermitilis MA-4680 1213097 NP_822715.1 CDS SAV_1539 NC_003155.4 1882639 1883631 R PF00941: FAD binding domain in molybdopterin dehydrogenase; oxidoreductase molybdopterin binding subunit complement(1882639..1883631) Streptomyces avermitilis MA-4680 1213098 NP_822716.1 CDS pucE NC_003155.4 1883628 1884200 R xanthine dehydrogenase complement(1883628..1884200) Streptomyces avermitilis MA-4680 1210214 NP_822717.1 CDS SAV_1541 NC_003155.4 1884456 1885052 D TetR family transcriptional regulator 1884456..1885052 Streptomyces avermitilis MA-4680 1213099 NP_822718.1 CDS SAV_1542 NC_003155.4 1885125 1886015 R PF01210: NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; dehydrogenase complement(1885125..1886015) Streptomyces avermitilis MA-4680 1213100 NP_822719.1 CDS SAV_1543 NC_003155.4 1886233 1887933 R hypothetical protein complement(1886233..1887933) Streptomyces avermitilis MA-4680 1213101 NP_822720.1 CDS SAV_1544 NC_003155.4 1888040 1889335 R PF01757: Acyltransferase family; hypothetical protein complement(1888040..1889335) Streptomyces avermitilis MA-4680 1213102 NP_822721.1 CDS SAV_1545 NC_003155.4 1889510 1890109 R hypothetical protein complement(1889510..1890109) Streptomyces avermitilis MA-4680 1213103 NP_822722.1 CDS SAV_1546 NC_003155.4 1890201 1890755 R PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein complement(1890201..1890755) Streptomyces avermitilis MA-4680 1213104 NP_822723.1 CDS rpiB1 NC_003155.4 1890784 1891254 R ribose-5-phosphate isomerase complement(1890784..1891254) Streptomyces avermitilis MA-4680 1210215 NP_822724.1 CDS SAV_1548 NC_003155.4 1891269 1892069 R carboxylesterase complement(1891269..1892069) Streptomyces avermitilis MA-4680 1213105 NP_822725.1 CDS SAV_1549 NC_003155.4 1892133 1893269 R esterase/lipase complement(1892133..1893269) Streptomyces avermitilis MA-4680 1213106 NP_822726.1 CDS pks2-1 NC_003155.4 1893266 1895794 R pks2 gene cluster; modular polyketide synthase complement(1893266..1895794) Streptomyces avermitilis MA-4680 1213107 NP_822727.1 CDS pks2-2 NC_003155.4 1895828 1910257 R pks2 gene cluster; modular polyketide synthase complement(1895828..1910257) Streptomyces avermitilis MA-4680 1213108 NP_822728.1 CDS pks2-3 NC_003155.4 1910558 1912282 R pks2 gene cluster; non-ribosomal peptide synthetase complement(1910558..1912282) Streptomyces avermitilis MA-4680 1213109 NP_822729.1 CDS SAV_1553 NC_003155.4 1912604 1913284 D pks2 gene cluster; methyltransferase 1912604..1913284 Streptomyces avermitilis MA-4680 1213110 NP_822730.1 CDS prpE1 NC_003155.4 1913338 1915320 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 1913338..1915320 Streptomyces avermitilis MA-4680 1213111 NP_822731.1 CDS SAV_1555 NC_003155.4 1915333 1916745 R PF07690: Major Facilitator Superfamily; integral membrane protein complement(1915333..1916745) Streptomyces avermitilis MA-4680 1213112 NP_822732.1 CDS SAV_1556 NC_003155.4 1916763 1917722 D AraC family transcription regulator 1916763..1917722 Streptomyces avermitilis MA-4680 1213113 NP_822733.1 CDS SAV_1557 NC_003155.4 1919349 1919771 R PF01894: Uncharacterised protein family UPF0047; hypothetical protein complement(1919349..1919771) Streptomyces avermitilis MA-4680 1213114 NP_822734.1 CDS SAV_1558 NC_003155.4 1920171 1920977 D ABC transporter permease 1920171..1920977 Streptomyces avermitilis MA-4680 1213115 NP_822735.1 CDS SAV_1559 NC_003155.4 1920950 1921732 D ABC transporter ATP-binding protein 1920950..1921732 Streptomyces avermitilis MA-4680 1213116 NP_822736.1 CDS SAV_1560 NC_003155.4 1921845 1922873 D sulfonate binding protein precursor 1921845..1922873 Streptomyces avermitilis MA-4680 1213117 NP_822737.1 CDS ssuD2 NC_003155.4 1922873 1924027 D PF00296: Luciferase-like monooxygenase; alkanesulfonate monooxygenase 1922873..1924027 Streptomyces avermitilis MA-4680 1210216 NP_822738.1 CDS SAV_1562 NC_003155.4 1924069 1925157 D PF00070: Pyridine nucleotide-disulphide oxidoreductase; oxidoreductase 1924069..1925157 Streptomyces avermitilis MA-4680 1213118 NP_822739.1 CDS pabC NC_003155.4 1925174 1926019 R aminodeoxychorismate lyase complement(1925174..1926019) Streptomyces avermitilis MA-4680 1210217 NP_822740.1 CDS SAV_1564 NC_003155.4 1926063 1927862 R ABC transporter ATP-binding protein complement(1926063..1927862) Streptomyces avermitilis MA-4680 1213119 NP_822741.1 CDS SAV_1565 NC_003155.4 1927957 1928412 D MarR family transcriptional regulator 1927957..1928412 Streptomyces avermitilis MA-4680 1213120 NP_822742.1 CDS SAV_1566 NC_003155.4 1928740 1928997 R hypothetical protein complement(1928740..1928997) Streptomyces avermitilis MA-4680 1213121 NP_822743.1 CDS SAV_1567 NC_003155.4 1929019 1930644 R hypothetical protein complement(1929019..1930644) Streptomyces avermitilis MA-4680 1213122 NP_822744.1 CDS SAV_1568 NC_003155.4 1930839 1931663 R lipoprotein complement(1930839..1931663) Streptomyces avermitilis MA-4680 1213123 NP_822745.1 CDS SAV_1569 NC_003155.4 1931874 1933736 D hypothetical protein 1931874..1933736 Streptomyces avermitilis MA-4680 1213124 NP_822746.1 CDS SAV_1570 NC_003155.4 1933733 1935514 D ABC transporter ATP-binding protein 1933733..1935514 Streptomyces avermitilis MA-4680 1213125 NP_822747.1 CDS SAV_1571 NC_003155.4 1936091 1936561 D hypothetical protein 1936091..1936561 Streptomyces avermitilis MA-4680 1213126 NP_822748.1 CDS rpmE2 NC_003155.4 1936716 1936991 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 1936716..1936991 Streptomyces avermitilis MA-4680 1210218 NP_822749.1 CDS SAV_1574 NC_003155.4 1937072 1937866 R PF04307: Predicted membrane-bound metal-dependent hydrolase (DUF457); integral membrane protein complement(1937072..1937866) Streptomyces avermitilis MA-4680 1213127 NP_822750.1 CDS SAV_1573 NC_003155.4 1937865 1940525 D PF00270: DEAD/DEAH box helicase; ATP-dependent helicase 1937865..1940525 Streptomyces avermitilis MA-4680 1213128 NP_822751.1 CDS tesB1 NC_003155.4 1940545 1941411 D PF02551: Acyl-CoA thioesterase; acyl-CoA thioesterase 1940545..1941411 Streptomyces avermitilis MA-4680 1210219 NP_822752.1 CDS SAV_1576 NC_003155.4 1941471 1942481 R hypothetical protein complement(1941471..1942481) Streptomyces avermitilis MA-4680 1213129 NP_822753.1 CDS SAV_1577 NC_003155.4 1942608 1943024 R PF03259: Roadblock/LC7 domain; hypothetical protein complement(1942608..1943024) Streptomyces avermitilis MA-4680 1213130 NP_822754.1 CDS SAV_1578 NC_003155.4 1943111 1943548 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 1943111..1943548 Streptomyces avermitilis MA-4680 1213131 NP_822755.1 CDS cvnD2 NC_003155.4 1943568 1944173 R multi-component regulatory system-2; ATP/GTP-binding protein complement(1943568..1944173) Streptomyces avermitilis MA-4680 1210220 NP_822756.1 CDS cvnC2 NC_003155.4 1944205 1944618 R multi-component regulatory system-2, PF05331: Protein of unknown function (DUF742); hypothetical protein complement(1944205..1944618) Streptomyces avermitilis MA-4680 1210221 NP_822757.1 CDS cvnB2 NC_003155.4 1944638 1945075 R multi-component regulatory system-2, PF03259: Roadblock/LC7 domain; hypothetical protein complement(1944638..1945075) Streptomyces avermitilis MA-4680 1210222 NP_822758.1 CDS cvnA2 NC_003155.4 1945072 1947624 R multi-component regulatory system-2; sensor-like histidine kinase complement(1945072..1947624) Streptomyces avermitilis MA-4680 1210223 NP_822759.1 CDS SAV_1583 NC_003155.4 1947688 1948419 R PF03707: Bacterial signalling protein N terminal repeat; integral membrane protein complement(1947688..1948419) Streptomyces avermitilis MA-4680 1213132 NP_822760.1 CDS SAV_1584 NC_003155.4 1948605 1949213 D methyltransferase 1948605..1949213 Streptomyces avermitilis MA-4680 1213133 NP_822761.1 CDS SAV_1585 NC_003155.4 1949240 1949998 R PF00561: alpha/beta hydrolase fold; hypothetical protein complement(1949240..1949998) Streptomyces avermitilis MA-4680 1213134 NP_822762.1 CDS SAV_1586 NC_003155.4 1950129 1950671 D PadR-like family transcriptional regulator 1950129..1950671 Streptomyces avermitilis MA-4680 1213135 NP_822763.1 CDS SAV_1587 NC_003155.4 1950648 1951553 R hypothetical protein complement(1950648..1951553) Streptomyces avermitilis MA-4680 1213136 NP_822764.1 CDS SAV_1588 NC_003155.4 1951608 1951949 D hypothetical protein 1951608..1951949 Streptomyces avermitilis MA-4680 1213137 NP_822765.1 CDS SAV_1589 NC_003155.4 1952105 1952986 D hypothetical protein 1952105..1952986 Streptomyces avermitilis MA-4680 1213138 NP_822766.1 CDS SAV_1590 NC_003155.4 1953112 1953348 R hypothetical protein complement(1953112..1953348) Streptomyces avermitilis MA-4680 1213139 NP_822767.1 CDS fadS1 NC_003155.4 1953419 1954480 R PF00487: Fatty acid desaturase; delta-6 fatty acid desaturase complement(1953419..1954480) Streptomyces avermitilis MA-4680 1210224 NP_822768.1 CDS helZ2 NC_003155.4 1954746 1957685 D SNF2/RAD54 family helicase 1954746..1957685 Streptomyces avermitilis MA-4680 1210225 NP_822769.1 CDS SAV_1593 NC_003155.4 1957682 1958959 D hypothetical protein 1957682..1958959 Streptomyces avermitilis MA-4680 1213140 NP_822770.1 CDS SAV_1594 NC_003155.4 1959084 1960367 R hypothetical protein complement(1959084..1960367) Streptomyces avermitilis MA-4680 1213141 NP_822771.1 CDS SAV_1595 NC_003155.4 1960490 1962097 R initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; 3-ketosteroid-delta-1-dehydrogenase complement(1960490..1962097) Streptomyces avermitilis MA-4680 1213142 NP_822772.1 CDS SAV_1596 NC_003155.4 1962456 1962950 D hypothetical protein 1962456..1962950 Streptomyces avermitilis MA-4680 1213143 NP_822773.1 CDS SAV_1597 NC_003155.4 1963035 1964003 R PF00248: Aldo/keto reductase family; oxidoreductase complement(1963035..1964003) Streptomyces avermitilis MA-4680 1213144 NP_822774.1 CDS SAV_1598 NC_003155.4 1964411 1965265 D PF00656: Caspase domain; hypothetical protein 1964411..1965265 Streptomyces avermitilis MA-4680 1213145 NP_822775.1 CDS SAV_1599 NC_003155.4 1965484 1966050 D PF03745: Domain of unknown function (DUF309); hypothetical protein 1965484..1966050 Streptomyces avermitilis MA-4680 1213146 NP_822776.1 CDS cobF NC_003155.4 1966110 1966880 D catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase 1966110..1966880 Streptomyces avermitilis MA-4680 1213147 NP_822777.1 CDS cobK NC_003155.4 1967656 1968402 R CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase complement(1967656..1968402) Streptomyces avermitilis MA-4680 1213148 NP_822778.1 CDS SAV_1602 NC_003155.4 1968424 1969197 R PF01925: Domain of unknown function DUF81; integral membrane protein complement(1968424..1969197) Streptomyces avermitilis MA-4680 1213149 NP_822779.1 CDS fadD7 NC_003155.4 1969300 1970811 R PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase complement(1969300..1970811) Streptomyces avermitilis MA-4680 1210227 NP_822780.1 CDS pcaF1 NC_003155.4 1970941 1972128 R PF00108: Thiolase, N-terminal domain; beta-ketoadipyl-CoA thiolase complement(1970941..1972128) Streptomyces avermitilis MA-4680 1210228 NP_822781.1 CDS mrgA1 NC_003155.4 1972321 1972803 D PF00210: ferritin-like domain; starvation-induced DNA protecting protein 1972321..1972803 Streptomyces avermitilis MA-4680 1213150 NP_822782.1 CDS SAV_1606 NC_003155.4 1972823 1973470 D PF00730: HhH-GPD superfamily base excision DNA repair protein; endonuclease III-like protein 1972823..1973470 Streptomyces avermitilis MA-4680 1213151 NP_822783.1 CDS SAV_1607 NC_003155.4 1973812 1975050 D PF01594: Domain of unknown function DUF20; integral membrane protein 1973812..1975050 Streptomyces avermitilis MA-4680 1213152 NP_822784.1 CDS SAV_1608 NC_003155.4 1975282 1975818 R MarR family transcriptional regulator complement(1975282..1975818) Streptomyces avermitilis MA-4680 1213153 NP_822785.1 CDS fprC NC_003155.4 1975840 1977057 R ferredoxin reductase complement(1975840..1977057) Streptomyces avermitilis MA-4680 1210229 NP_822786.1 CDS fdxB NC_003155.4 1977054 1977251 R ferredoxin complement(1977054..1977251) Streptomyces avermitilis MA-4680 1210230 NP_822787.1 CDS cyp7 NC_003155.4 1977286 1978527 R CYP105Q1, fdxB and fprC are located at downstream; cytochrome P450 complement(1977286..1978527) Streptomyces avermitilis MA-4680 1210231 NP_822788.1 CDS SAV_1612 NC_003155.4 1978871 1979575 R two-component system response regulator complement(1978871..1979575) Streptomyces avermitilis MA-4680 1213154 NP_822789.1 CDS SAV_1613 NC_003155.4 1979878 1980648 D PF00106: short chain dehydrogenase; dehydrogenase 1979878..1980648 Streptomyces avermitilis MA-4680 1213155 NP_822790.1 CDS SAV_1614 NC_003155.4 1980949 1982277 R PF07690: Major Facilitator Superfamily; benzoate transport protein complement(1980949..1982277) Streptomyces avermitilis MA-4680 1213156 NP_822791.1 CDS xylE NC_003155.4 1982532 1983482 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; catechol 2,3-dioxygenase complement(1982532..1983482) Streptomyces avermitilis MA-4680 1210232 NP_822792.1 CDS SAV_1616 NC_003155.4 1983493 1984566 R transmenmbrane protein complement(1983493..1984566) Streptomyces avermitilis MA-4680 1213157 NP_822793.1 CDS SAV_1617 NC_003155.4 1984590 1985300 R hypothetical protein complement(1984590..1985300) Streptomyces avermitilis MA-4680 1213158 NP_822794.1 CDS SAV_1618 NC_003155.4 1985297 1986046 R PF02585: Uncharacterised LmbE-like protein, COG2120; hypothetical protein complement(1985297..1986046) Streptomyces avermitilis MA-4680 1213159 NP_822795.1 CDS SAV_1619 NC_003155.4 1986092 1986742 R GntR family transcriptional regulator complement(1986092..1986742) Streptomyces avermitilis MA-4680 1213160 NP_822796.1 CDS SAV_1620 NC_003155.4 1987073 1988569 R amino acid permease complement(1987073..1988569) Streptomyces avermitilis MA-4680 1213161 NP_822797.1 CDS SAV_1621 NC_003155.4 1988569 1990113 R PF00732: GMC oxidoreductase; oxidoreductase complement(1988569..1990113) Streptomyces avermitilis MA-4680 1213162 NP_822798.1 CDS gbsA1 NC_003155.4 1990145 1991611 R glycine betaine aldehyde dehydrogenase complement(1990145..1991611) Streptomyces avermitilis MA-4680 1210233 NP_822799.1 CDS SAV_1623 NC_003155.4 1992287 1992997 D transketolase A subunit 1992287..1992997 Streptomyces avermitilis MA-4680 1213163 NP_822800.1 CDS SAV_1624 NC_003155.4 1993096 1994007 D transketolase B subunit 1993096..1994007 Streptomyces avermitilis MA-4680 1213164 NP_822801.1 CDS SAV_1625 NC_003155.4 1994047 1994535 R PF04944: Uncharacterised BCR (COG3801); hypothetical protein complement(1994047..1994535) Streptomyces avermitilis MA-4680 1213165 NP_822802.1 CDS SAV_1626 NC_003155.4 1994576 1995481 R LysR family transcriptional regulator complement(1994576..1995481) Streptomyces avermitilis MA-4680 1213166 NP_822803.1 CDS kbl NC_003155.4 1995767 1996963 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(1995767..1996963) Streptomyces avermitilis MA-4680 1210235 NP_822804.1 CDS tdh NC_003155.4 1996980 1998008 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(1996980..1998008) Streptomyces avermitilis MA-4680 1210236 NP_822805.1 CDS SAV_1629 NC_003155.4 1998258 1998839 R PF01590: GAF domain; hypothetical protein complement(1998258..1998839) Streptomyces avermitilis MA-4680 1213167 NP_822806.1 CDS cvnD3 NC_003155.4 1998868 1999416 R multi-component regulatory system-3; ATP/GTP-binding protein complement(1998868..1999416) Streptomyces avermitilis MA-4680 1210237 NP_822807.1 CDS cvnC3 NC_003155.4 1999445 1999765 R multi-component regulatory system-3, PF05331: Protein of unknown function (DUF742); hypothetical protein complement(1999445..1999765) Streptomyces avermitilis MA-4680 1210238 NP_822808.1 CDS cvnB3 NC_003155.4 1999819 2000253 R multi-component regulatory system-3, PF03259: Roadblock/LC7 domain; hypothetical protein complement(1999819..2000253) Streptomyces avermitilis MA-4680 1210239 NP_822809.1 CDS cvnA3 NC_003155.4 2000524 2002077 R multi-component regulatory system-3; sensor-like histidine kinase complement(2000524..2002077) Streptomyces avermitilis MA-4680 1210240 NP_822810.1 CDS SAV_1634 NC_003155.4 2002445 2003665 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(2002445..2003665) Streptomyces avermitilis MA-4680 1213168 NP_822811.1 CDS SAV_1635 NC_003155.4 2003675 2004457 D PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein 2003675..2004457 Streptomyces avermitilis MA-4680 1213169 NP_822812.1 CDS rocG NC_003155.4 2004635 2005813 D glutamate dehydrogenase 2004635..2005813 Streptomyces avermitilis MA-4680 1210241 NP_822813.1 CDS SAV_1637 NC_003155.4 2005912 2006532 D TetR family transcriptional regulator 2005912..2006532 Streptomyces avermitilis MA-4680 1213170 NP_822814.1 CDS SAV_1638 NC_003155.4 2006611 2007396 R PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein complement(2006611..2007396) Streptomyces avermitilis MA-4680 1213171 NP_822815.1 CDS SAV_1639 NC_003155.4 2007541 2008260 R hypothetical protein complement(2007541..2008260) Streptomyces avermitilis MA-4680 1213172 NP_822816.1 CDS SAV_1640 NC_003155.4 2008712 2009617 R PF01551: Peptidase family M23; peptidase complement(2008712..2009617) Streptomyces avermitilis MA-4680 1213173 NP_822817.1 CDS agaB3 NC_003155.4 2010083 2012185 R alpha-galactosidase complement(2010083..2012185) Streptomyces avermitilis MA-4680 1210242 NP_822818.1 CDS ptpA2 NC_003155.4 2012323 2013120 D conventional protein tyrosine phosphatase 2012323..2013120 Streptomyces avermitilis MA-4680 1213174 NP_822819.1 CDS SAV_1643 NC_003155.4 2013146 2013340 R small hydrophobic protein complement(2013146..2013340) Streptomyces avermitilis MA-4680 1213175 NP_822820.1 CDS SAV_1644 NC_003155.4 2013292 2013918 R regulatory protein complement(2013292..2013918) Streptomyces avermitilis MA-4680 1213176 NP_822821.1 CDS SAV_1645 NC_003155.4 2014006 2015436 R aminotransferase complement(2014006..2015436) Streptomyces avermitilis MA-4680 1213177 NP_822822.1 CDS dxs1 NC_003155.4 2015433 2017331 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(2015433..2017331) Streptomyces avermitilis MA-4680 1210243 NP_822823.1 CDS ispG NC_003155.4 2017360 2018517 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2017360..2018517) Streptomyces avermitilis MA-4680 1210244 NP_822824.1 CDS SAV_1648 NC_003155.4 2018522 2019544 R PF04055: radical SAM superfamily domain; hypothetical protein complement(2018522..2019544) Streptomyces avermitilis MA-4680 1213178 NP_822825.1 CDS SAV_1649 NC_003155.4 2019550 2020194 R PF01048: Phosphorylase family; hypothetical protein complement(2019550..2020194) Streptomyces avermitilis MA-4680 1213179 NP_822826.1 CDS hopA NC_003155.4 2020191 2022191 R squalene/hopene gene cluster, shc; squalene-hopene cyclase complement(2020191..2022191) Streptomyces avermitilis MA-4680 1210245 NP_822827.1 CDS hopB NC_003155.4 2022306 2023436 R squalene/hopene gene cluster, probably farnesyl pyrophosphate synthase; polyprenyl diphosphate synthase complement(2022306..2023436) Streptomyces avermitilis MA-4680 1210246 NP_822828.1 CDS hopC NC_003155.4 2023433 2024860 R squalene/hopene gene cluster, sqd; squalene/phytoene dehydrogenase complement(2023433..2024860) Streptomyces avermitilis MA-4680 1210247 NP_822829.1 CDS hopD NC_003155.4 2024997 2025947 R squalene/hopene gene cluster, sqs1; squalene/phytoene synthase complement(2024997..2025947) Streptomyces avermitilis MA-4680 1210248 NP_822830.1 CDS hopE NC_003155.4 2025944 2026846 R squalene/hopene gene cluster, sqs2; squalene/phytoene synthase complement(2025944..2026846) Streptomyces avermitilis MA-4680 1210249 NP_822831.1 CDS SAV_1655 NC_003155.4 2027207 2027986 R ABC transporter ATP-binding protein complement(2027207..2027986) Streptomyces avermitilis MA-4680 1213180 NP_822832.1 CDS SAV_1656 NC_003155.4 2027979 2028908 R ABC transporter permease complement(2027979..2028908) Streptomyces avermitilis MA-4680 1213181 NP_822833.1 CDS SAV_1657 NC_003155.4 2029006 2029890 R glycosyltransferase complement(2029006..2029890) Streptomyces avermitilis MA-4680 1213182 NP_822834.1 CDS SAV_1658 NC_003155.4 2029887 2030570 R transferase complement(2029887..2030570) Streptomyces avermitilis MA-4680 1213183 NP_822835.1 CDS gldA NC_003155.4 2030644 2031705 R glycerol 1-phosphate dehydrogenase complement(2030644..2031705) Streptomyces avermitilis MA-4680 1210250 NP_822836.1 CDS SAV_1660 NC_003155.4 2031693 2032445 R nucleotide sugar-1-phosphate transferase complement(2031693..2032445) Streptomyces avermitilis MA-4680 1213184 NP_822837.1 CDS SAV_1661 NC_003155.4 2032442 2034163 R transferase complement(2032442..2034163) Streptomyces avermitilis MA-4680 1213185 NP_822838.1 CDS galE6 NC_003155.4 2034577 2035557 D UDP-glucose 4-epimerase 2034577..2035557 Streptomyces avermitilis MA-4680 1210251 NP_822839.1 CDS idi NC_003155.4 2035914 2036507 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2035914..2036507 Streptomyces avermitilis MA-4680 1210252 NP_822840.1 CDS SAV_1664 NC_003155.4 2036581 2037156 R regulatory protein complement(2036581..2037156) Streptomyces avermitilis MA-4680 1213186 NP_822841.1 CDS echA6 NC_003155.4 2037350 2038099 D enoyl-CoA hydratase 2037350..2038099 Streptomyces avermitilis MA-4680 1210253 NP_822842.1 CDS thiJ NC_003155.4 2038086 2038721 R 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme complement(2038086..2038721) Streptomyces avermitilis MA-4680 1210254 NP_822843.1 CDS SAV_1667 NC_003155.4 2038747 2039751 R AraC family transcription regulator complement(2038747..2039751) Streptomyces avermitilis MA-4680 1213187 NP_822844.1 CDS SAV_1668 NC_003155.4 2039912 2040679 D hypothetical protein 2039912..2040679 Streptomyces avermitilis MA-4680 1213188 NP_822845.1 CDS SAV_1669 NC_003155.4 2040961 2043393 D transcription accessory protein 2040961..2043393 Streptomyces avermitilis MA-4680 1213189 NP_822846.1 CDS SAV_1670 NC_003155.4 2043550 2045190 R ABC transporter ATP-binding protein complement(2043550..2045190) Streptomyces avermitilis MA-4680 1213190 NP_822847.1 CDS SAV_1671 NC_003155.4 2045266 2046285 R oxidoreductase complement(2045266..2046285) Streptomyces avermitilis MA-4680 1213191 NP_822848.1 CDS dao NC_003155.4 2046352 2047305 D D-amino acid oxidase 2046352..2047305 Streptomyces avermitilis MA-4680 1210255 NP_822849.1 CDS SAV_1673 NC_003155.4 2047310 2048605 R PF00246: Zinc carboxypeptidase; carboxypeptidase complement(2047310..2048605) Streptomyces avermitilis MA-4680 1213192 NP_822850.1 CDS SAV_1674 NC_003155.4 2048602 2050632 R catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase complement(2048602..2050632) Streptomyces avermitilis MA-4680 1213193 NP_822851.1 CDS SAV_1675 NC_003155.4 2050745 2052238 D PF01433: Peptidase family M1; metallopeptidase 2050745..2052238 Streptomyces avermitilis MA-4680 1213194 NP_822852.1 CDS SAV_1676 NC_003155.4 2052475 2052954 R hypothetical protein complement(2052475..2052954) Streptomyces avermitilis MA-4680 1213195 NP_822853.1 CDS ansP2 NC_003155.4 2052998 2054461 R L-asparagine permease complement(2052998..2054461) Streptomyces avermitilis MA-4680 1213196 NP_822854.1 CDS SAV_1678 NC_003155.4 2054785 2055480 D MerR family transcriptional regulator 2054785..2055480 Streptomyces avermitilis MA-4680 1213197 NP_822855.1 CDS SAV_1679 NC_003155.4 2055588 2056229 R PF00106: short chain dehydrogenase; dehydrogenase complement(2055588..2056229) Streptomyces avermitilis MA-4680 1213198 NP_822856.1 CDS fadB1 NC_003155.4 2056428 2058635 R similar to glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a: including enoyl-CoA hydratase; 3-2-trans-enoyl-CoA isomerase; 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase; fatty acid oxidation complex alpha-subunit complement(2056428..2058635) Streptomyces avermitilis MA-4680 1210256 NP_822857.1 CDS fadA4 NC_003155.4 2058688 2059902 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(2058688..2059902) Streptomyces avermitilis MA-4680 1210257 NP_822858.1 CDS mcr NC_003155.4 2060054 2061247 R PF02515: CoA-transferase family III; fatty acid-CoA racemase complement(2060054..2061247) Streptomyces avermitilis MA-4680 1213199 NP_822859.1 CDS SAV_1683 NC_003155.4 2061478 2062653 D hypothetical protein 2061478..2062653 Streptomyces avermitilis MA-4680 1213200 NP_822860.1 CDS SAV_1684 NC_003155.4 2062697 2063386 R endonuclease V complement(2062697..2063386) Streptomyces avermitilis MA-4680 1213201 NP_822861.1 CDS SAV_1685 NC_003155.4 2063421 2063747 R hypothetical protein complement(2063421..2063747) Streptomyces avermitilis MA-4680 1213202 NP_822862.1 CDS SAV_1686 NC_003155.4 2063861 2064913 R PF02012: BNR/Asp-box repeat; oxidoreductase complement(2063861..2064913) Streptomyces avermitilis MA-4680 1213203 NP_822863.1 CDS ssgA5 NC_003155.4 2065246 2065662 D PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein 2065246..2065662 Streptomyces avermitilis MA-4680 1213204 NP_822864.1 CDS SAV_1688 NC_003155.4 2065923 2066678 R hypothetical protein complement(2065923..2066678) Streptomyces avermitilis MA-4680 1213205 NP_822865.1 CDS SAV_1689 NC_003155.4 2066918 2068537 D ABC transporter ATP-binding protein 2066918..2068537 Streptomyces avermitilis MA-4680 1213206 NP_822866.1 CDS ddh NC_003155.4 2068821 2069597 D dimethylarginine dimethylaminohydrolase 2068821..2069597 Streptomyces avermitilis MA-4680 1210258 NP_822867.1 CDS SAV_1691 NC_003155.4 2069818 2070792 D acyl-ACP desaturase 2069818..2070792 Streptomyces avermitilis MA-4680 1213207 NP_822868.1 CDS SAV_1692 NC_003155.4 2070860 2071630 R hypothetical protein complement(2070860..2071630) Streptomyces avermitilis MA-4680 1213208 NP_822869.1 CDS whmD NC_003155.4 2071759 2072004 R WhiB-family transcriptional regulator complement(2071759..2072004) Streptomyces avermitilis MA-4680 1213209 NP_822870.1 CDS SAV_1694 NC_003155.4 2072296 2073087 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hydroxylase 2072296..2073087 Streptomyces avermitilis MA-4680 1213210 NP_822871.1 CDS SAV_1695 NC_003155.4 2073171 2074217 R LacI family transcriptional regulator complement(2073171..2074217) Streptomyces avermitilis MA-4680 1213211 NP_822872.1 CDS SAV_1696 NC_003155.4 2074412 2075428 R hypothetical protein complement(2074412..2075428) Streptomyces avermitilis MA-4680 1213212 NP_822873.1 CDS ligC NC_003155.4 2075503 2076573 D catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; ATP-dependent DNA ligase 2075503..2076573 Streptomyces avermitilis MA-4680 1210259 NP_822874.1 CDS SAV_1698 NC_003155.4 2076901 2077878 D hypothetical protein 2076901..2077878 Streptomyces avermitilis MA-4680 1213213 NP_822875.1 CDS SAV_1699 NC_003155.4 2077925 2078392 R MarR family transcriptional regulator complement(2077925..2078392) Streptomyces avermitilis MA-4680 1213214 NP_822876.1 CDS scoA NC_003155.4 2078649 2079431 D PF01144: Coenzyme A transferase; 3-oxoacid CoA-transferase subunit A 2078649..2079431 Streptomyces avermitilis MA-4680 1210260 NP_822877.1 CDS scoB NC_003155.4 2079431 2080078 D PF01144: Coenzyme A transferase; 3-oxoacid CoA-transferase subunit B 2079431..2080078 Streptomyces avermitilis MA-4680 1210261 NP_822878.1 CDS pcaF2 NC_003155.4 2080075 2080491 D PF00108: Thiolase, N-terminal domain; beta-ketoadipyl-CoA thiolase 2080075..2080491 Streptomyces avermitilis MA-4680 1210262 NP_822879.1 CDS pcaH NC_003155.4 2080504 2081274 D PF00775: Dioxygenase; protocatechuate 3,4-dioxygenase beta subunit 2080504..2081274 Streptomyces avermitilis MA-4680 1210263 NP_822880.1 CDS pcaG NC_003155.4 2081220 2081840 D PF00775: Dioxygenase; protocatechuate 3,4-dioxygenase alpha subunit 2081220..2081840 Streptomyces avermitilis MA-4680 1210264 NP_822881.1 CDS pcaB NC_003155.4 2081837 2083174 D PF00206: Lyase; 3-carboxy-cis,cis-muconate cycloisomerase 2081837..2083174 Streptomyces avermitilis MA-4680 1210265 NP_822882.1 CDS pcaL1 NC_003155.4 2083171 2084310 D PF02627: Carboxymuconolactone decarboxylase family; 3-oxoadipate enol-lactone hydrolase 2083171..2084310 Streptomyces avermitilis MA-4680 1210266 NP_822883.1 CDS SAV_1707 NC_003155.4 2084414 2087101 R regulatory protein complement(2084414..2087101) Streptomyces avermitilis MA-4680 1213215 NP_822884.1 CDS SAV_1708 NC_003155.4 2087282 2088634 D PF00083: Sugar (and other) transporter; integral membrane transport protein 2087282..2088634 Streptomyces avermitilis MA-4680 1213216 NP_822885.1 CDS anmK NC_003155.4 2088639 2089793 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2088639..2089793 Streptomyces avermitilis MA-4680 1213217 NP_822886.1 CDS SAV_1710 NC_003155.4 2089889 2090881 D hypothetical protein 2089889..2090881 Streptomyces avermitilis MA-4680 1213218 NP_822887.1 CDS SAV_1711 NC_003155.4 2091029 2091643 R TetR family transcriptional regulator complement(2091029..2091643) Streptomyces avermitilis MA-4680 1213219 NP_822888.1 CDS SAV_1712 NC_003155.4 2091875 2092885 D hypothetical protein 2091875..2092885 Streptomyces avermitilis MA-4680 1213220 NP_822889.1 CDS SAV_1713 NC_003155.4 2092882 2093826 D integral membrane protein 2092882..2093826 Streptomyces avermitilis MA-4680 1213221 NP_822890.1 CDS SAV_1714 NC_003155.4 2093917 2094774 R PF03803: Scramblase; hypothetical protein complement(2093917..2094774) Streptomyces avermitilis MA-4680 1213222 NP_822891.1 CDS plcA NC_003155.4 2094827 2096878 R PF04185: Phosphoesterase family; non-hemolytic phospholipase C complement(2094827..2096878) Streptomyces avermitilis MA-4680 1210267 NP_822892.1 CDS SAV_1716 NC_003155.4 2097186 2097869 R LysR family transcriptional regulator complement(2097186..2097869) Streptomyces avermitilis MA-4680 1213223 NP_822893.1 CDS SAV_1717 NC_003155.4 2097860 2098342 R hypothetical protein complement(2097860..2098342) Streptomyces avermitilis MA-4680 1213224 NP_822894.1 CDS SAV_1718 NC_003155.4 2098481 2098867 D substrate-binding protein 2098481..2098867 Streptomyces avermitilis MA-4680 1213225 NP_822895.1 CDS SAV_1719 NC_003155.4 2098919 2099743 D ABC transporter substrate-binding protein 2098919..2099743 Streptomyces avermitilis MA-4680 1213226 NP_822896.1 CDS SAV_1720 NC_003155.4 2099740 2100609 D ABC transporter permease 2099740..2100609 Streptomyces avermitilis MA-4680 1213227 NP_822897.1 CDS SAV_1721 NC_003155.4 2100606 2101700 D ABC transporter ATP-binding protein 2100606..2101700 Streptomyces avermitilis MA-4680 1213228 NP_822898.1 CDS SAV_1722 NC_003155.4 2101766 2102668 D PF03473: MOSC domain; hypothetical protein 2101766..2102668 Streptomyces avermitilis MA-4680 1213229 NP_822899.1 CDS SAV_1723 NC_003155.4 2102982 2105156 R mycodextranase complement(2102982..2105156) Streptomyces avermitilis MA-4680 1213230 NP_822900.1 CDS aglA1 NC_003155.4 2105214 2106815 R alpha-glucosidase complement(2105214..2106815) Streptomyces avermitilis MA-4680 1210268 NP_822901.1 CDS SAV_1725 NC_003155.4 2106847 2107722 R ABC transporter permease complement(2106847..2107722) Streptomyces avermitilis MA-4680 1213231 NP_822902.1 CDS SAV_1726 NC_003155.4 2107719 2108675 R ABC transporter permease complement(2107719..2108675) Streptomyces avermitilis MA-4680 1213232 NP_822903.1 CDS SAV_1727 NC_003155.4 2108681 2110021 R sugar uptake sugar ABC transporter substrate-binding protein complement(2108681..2110021) Streptomyces avermitilis MA-4680 1213233 NP_822904.1 CDS SAV_1728 NC_003155.4 2110168 2111160 R LacI family transcriptional regulator complement(2110168..2111160) Streptomyces avermitilis MA-4680 1213234 NP_822905.1 CDS SAV_1729 NC_003155.4 2111207 2111935 R GntR family transcriptional regulator complement(2111207..2111935) Streptomyces avermitilis MA-4680 1213235 NP_822906.1 CDS SAV_1730 NC_003155.4 2111948 2112949 R proline racemase complement(2111948..2112949) Streptomyces avermitilis MA-4680 1213236 NP_822907.1 CDS dapA1 NC_003155.4 2112964 2113854 R dihydrodipicolinate synthase complement(2112964..2113854) Streptomyces avermitilis MA-4680 1210269 NP_822908.1 CDS SAV_1732 NC_003155.4 2113851 2115350 R oxidase complement(2113851..2115350) Streptomyces avermitilis MA-4680 1213237 NP_822909.1 CDS SAV_1733 NC_003155.4 2115340 2115639 R hypothetical protein complement(2115340..2115639) Streptomyces avermitilis MA-4680 1213238 NP_822910.1 CDS SAV_1734 NC_003155.4 2115636 2116883 R PF01266: FAD dependent oxidoreductase; oxidoreductase complement(2115636..2116883) Streptomyces avermitilis MA-4680 1213239 NP_822911.1 CDS SAV_1735 NC_003155.4 2116980 2117837 R ABC transporter permease complement(2116980..2117837) Streptomyces avermitilis MA-4680 1213240 NP_822912.1 CDS SAV_1736 NC_003155.4 2117818 2118711 R ABC transporter permease complement(2117818..2118711) Streptomyces avermitilis MA-4680 1213241 NP_822913.1 CDS SAV_1737 NC_003155.4 2118719 2119963 R ABC transporter complement(2118719..2119963) Streptomyces avermitilis MA-4680 1213242 NP_822914.1 CDS SAV_1738 NC_003155.4 2119989 2121026 R ABC transporter ATP-binding protein complement(2119989..2121026) Streptomyces avermitilis MA-4680 1213243 NP_822915.1 CDS SAV_1739 NC_003155.4 2121131 2121886 D GntR family transcriptional regulator 2121131..2121886 Streptomyces avermitilis MA-4680 1213244 NP_822916.1 CDS SAV_1740 NC_003155.4 2121925 2122722 D PF02743: Cache domain; hypothetical protein 2121925..2122722 Streptomyces avermitilis MA-4680 1213245 NP_822917.1 CDS SAV_1741 NC_003155.4 2122777 2123445 R PF00989: PAS domain; hypothetical protein complement(2122777..2123445) Streptomyces avermitilis MA-4680 1213246 NP_822918.1 CDS SAV_1742 NC_003155.4 2123698 2124354 D transcriptional regulator 2123698..2124354 Streptomyces avermitilis MA-4680 1213247 NP_822919.1 CDS SAV_1743 NC_003155.4 2124387 2124917 D hypothetical protein 2124387..2124917 Streptomyces avermitilis MA-4680 1213248 NP_822920.1 CDS SAV_1744 NC_003155.4 2124930 2126135 D integral membrane protein 2124930..2126135 Streptomyces avermitilis MA-4680 1213249 NP_822921.1 CDS SAV_1745 NC_003155.4 2126119 2127579 D PF01360: Monooxygenase; monooxygenase 2126119..2127579 Streptomyces avermitilis MA-4680 1213250 NP_822922.1 CDS SAV_1746 NC_003155.4 2127643 2128686 R PF00561: alpha/beta hydrolase fold; hydrolase complement(2127643..2128686) Streptomyces avermitilis MA-4680 1213251 NP_822923.1 CDS SAV_1747 NC_003155.4 2128854 2129156 D hypothetical protein 2128854..2129156 Streptomyces avermitilis MA-4680 1213252 NP_822924.1 CDS pptA2 NC_003155.4 2129199 2129888 R PF01648: 4'-phosphopantetheinyl transferase superfamily; phosphopantetheinyl transferase complement(2129199..2129888) Streptomyces avermitilis MA-4680 1210270 NP_822925.1 CDS SAV_1749 NC_003155.4 2129885 2130757 R SimX4-like protein complement(2129885..2130757) Streptomyces avermitilis MA-4680 1213253 NP_822926.1 CDS SAV_1750 NC_003155.4 2131075 2132220 D PF02222: ATP-grasp domain; hypothetical protein 2131075..2132220 Streptomyces avermitilis MA-4680 1213254 NP_822927.1 CDS chiA2 NC_003155.4 2132343 2134028 D chitinase A 2132343..2134028 Streptomyces avermitilis MA-4680 1210271 NP_822928.1 CDS SAV_1752 NC_003155.4 2134074 2135324 R PF01120: Alpha-L-fucosidase; glycosyl hydrolase complement(2134074..2135324) Streptomyces avermitilis MA-4680 1213255 NP_822929.1 CDS ama1 NC_003155.4 2135431 2138499 R alpha-mannosidase complement(2135431..2138499) Streptomyces avermitilis MA-4680 1210272 NP_822930.1 CDS bglA1 NC_003155.4 2138564 2139901 R 6-phospho-beta-glucosidase complement(2138564..2139901) Streptomyces avermitilis MA-4680 1210273 NP_822931.1 CDS SAV_1755 NC_003155.4 2139898 2140683 R DeoR family transcriptional regulator complement(2139898..2140683) Streptomyces avermitilis MA-4680 1213256 NP_822932.1 CDS SAV_1756 NC_003155.4 2140789 2141826 D carbohydrate kinase 2140789..2141826 Streptomyces avermitilis MA-4680 1213257 NP_822933.1 CDS SAV_1757 NC_003155.4 2141900 2143195 D sugar ABC transporter substrate-binding protein 2141900..2143195 Streptomyces avermitilis MA-4680 1213258 NP_822934.1 CDS SAV_1758 NC_003155.4 2143197 2144159 D sugar ABC transporter permease 2143197..2144159 Streptomyces avermitilis MA-4680 1213259 NP_822935.1 CDS SAV_1759 NC_003155.4 2144172 2145008 D sugar ABC transporter permease 2144172..2145008 Streptomyces avermitilis MA-4680 1213260 NP_822936.1 CDS bga4 NC_003155.4 2145008 2147932 D beta-galactosidase 2145008..2147932 Streptomyces avermitilis MA-4680 1210274 NP_822937.1 CDS SAV_1761 NC_003155.4 2148133 2149821 D PF02231: PHP domain N-terminal region; hypothetical protein 2148133..2149821 Streptomyces avermitilis MA-4680 1213261 NP_822938.1 CDS SAV_1762 NC_003155.4 2150017 2152782 R similar to StaR of Streptomyces toyocaensis NRRL15009; hypothetical protein complement(2150017..2152782) Streptomyces avermitilis MA-4680 1213262 NP_822939.1 CDS SAV_1763 NC_003155.4 2153091 2154362 D PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein 2153091..2154362 Streptomyces avermitilis MA-4680 1213263 NP_822940.1 CDS lamA1 NC_003155.4 2155064 2156464 D endo-1,3-beta-glucanase 2155064..2156464 Streptomyces avermitilis MA-4680 1210275 NP_822941.1 CDS SAV_1765 NC_003155.4 2156557 2157453 R AraC family transcription regulator complement(2156557..2157453) Streptomyces avermitilis MA-4680 1213264 NP_822942.1 CDS tkt1 NC_003155.4 2157594 2159675 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2157594..2159675 Streptomyces avermitilis MA-4680 1210276 NP_822943.1 CDS tal1 NC_003155.4 2159695 2160831 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 2159695..2160831 Streptomyces avermitilis MA-4680 1210277 NP_822944.1 CDS zwf1 NC_003155.4 2160828 2162474 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2160828..2162474 Streptomyces avermitilis MA-4680 1210278 NP_822945.1 CDS opcA1 NC_003155.4 2162471 2163406 D oxppcycle protein 2162471..2163406 Streptomyces avermitilis MA-4680 1213265 NP_822946.1 CDS pgi NC_003155.4 2163399 2165048 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 2163399..2165048 Streptomyces avermitilis MA-4680 1210279 NP_822947.1 CDS gnd1 NC_003155.4 2165064 2165942 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 2165064..2165942 Streptomyces avermitilis MA-4680 1210280 NP_822948.1 CDS SAV_1772 NC_003155.4 2165949 2166560 D mutase 2165949..2166560 Streptomyces avermitilis MA-4680 1213266 NP_822949.1 CDS terB NC_003155.4 2166642 2167097 D PF05099: Tellurite resistance protein TerB; tellurium resistance protein 2166642..2167097 Streptomyces avermitilis MA-4680 1213267 NP_822950.1 CDS SAV_1774 NC_003155.4 2167468 2170362 D PF03098: animal haem peroxidase; peroxidase 2167468..2170362 Streptomyces avermitilis MA-4680 1213268 NP_822951.1 CDS SAV_1775 NC_003155.4 2170472 2171929 D hypothetical protein 2170472..2171929 Streptomyces avermitilis MA-4680 1213269 NP_822952.1 CDS SAV_1776 NC_003155.4 2171936 2173741 R sugar phosphate isomerase/epimerase complement(2171936..2173741) Streptomyces avermitilis MA-4680 1210281 NP_822953.1 CDS aroE NC_003155.4 2173767 2174642 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(2173767..2174642) Streptomyces avermitilis MA-4680 1210282 NP_822954.1 CDS SAV_1778 NC_003155.4 2174818 2175483 D TetR family transcriptional regulator 2174818..2175483 Streptomyces avermitilis MA-4680 1213270 NP_822955.1 CDS SAV_1779 NC_003155.4 2175736 2177088 D PF00083: Sugar (and other) transporter; 3-(2-hydroxyphenyl) propionic acid transporter 2175736..2177088 Streptomyces avermitilis MA-4680 1213271 NP_822956.1 CDS SAV_1780 NC_003155.4 2177265 2177702 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(2177265..2177702) Streptomyces avermitilis MA-4680 1213272 NP_822957.1 CDS SAV_1781 NC_003155.4 2177771 2178355 D TetR family transcriptional regulator 2177771..2178355 Streptomyces avermitilis MA-4680 1213273 NP_822958.1 CDS SAV_1782 NC_003155.4 2178352 2179725 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 2178352..2179725 Streptomyces avermitilis MA-4680 1213274 NP_822959.1 CDS SAV_1783 NC_003155.4 2179785 2181011 D PF00144: Beta-lactamase; hypothetical protein 2179785..2181011 Streptomyces avermitilis MA-4680 1213275 NP_822960.1 CDS SAV_1784 NC_003155.4 2181020 2181445 R PF07366: Protein of unknown function (DUF1486); hypothetical protein complement(2181020..2181445) Streptomyces avermitilis MA-4680 1213276 NP_822961.1 CDS SAV_1785 NC_003155.4 2181486 2182337 R hypothetical protein complement(2181486..2182337) Streptomyces avermitilis MA-4680 1213277 NP_822962.1 CDS SAV_1786 NC_003155.4 2182334 2183068 R MerR family transcriptional regulator complement(2182334..2183068) Streptomyces avermitilis MA-4680 1213278 NP_822963.1 CDS SAV_1787 NC_003155.4 2183193 2184347 R PF03435: Saccharopine dehydrogenase; saccharopine dehydrogenase complement(2183193..2184347) Streptomyces avermitilis MA-4680 1213279 NP_822964.1 CDS SAV_1788 NC_003155.4 2184340 2185449 R PF05222: Alanine dehydrogenase/PNT, N-terminal domain; saccharopine dehydrogenase complement(2184340..2185449) Streptomyces avermitilis MA-4680 1213280 NP_822965.1 CDS SAV_1789 NC_003155.4 2185446 2186591 R sarcosine oxidase subunit beta complement(2185446..2186591) Streptomyces avermitilis MA-4680 1213281 NP_822966.1 CDS arcB1 NC_003155.4 2186588 2187568 R ornithine cyclodeaminase complement(2186588..2187568) Streptomyces avermitilis MA-4680 1210283 NP_822967.1 CDS ribA2 NC_003155.4 2187813 2188505 R GTP cyclohydrolase II complement(2187813..2188505) Streptomyces avermitilis MA-4680 1210284 NP_822968.1 CDS SAV_1792 NC_003155.4 2188543 2189343 D PF02633: Creatinine amidohydrolase; hypothetical protein 2188543..2189343 Streptomyces avermitilis MA-4680 1213282 NP_822969.1 CDS SAV_1793 NC_003155.4 2189175 2190674 R PF03706: Uncharacterised protein family (UPF0104); hypothetical protein complement(2189175..2190674) Streptomyces avermitilis MA-4680 1213283 NP_822970.1 CDS SAV_1794 NC_003155.4 2190671 2191627 R hypothetical protein complement(2190671..2191627) Streptomyces avermitilis MA-4680 1213284 NP_822971.1 CDS SAV_1795 NC_003155.4 2191624 2192766 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(2191624..2192766) Streptomyces avermitilis MA-4680 1213285 NP_822972.1 CDS SAV_1796 NC_003155.4 2192859 2193257 R PF01242: 6-pyruvoyl tetrahydropterin synthase; hypothetical protein complement(2192859..2193257) Streptomyces avermitilis MA-4680 1213286 NP_822973.1 CDS SAV_1797 NC_003155.4 2193432 2194412 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(2193432..2194412) Streptomyces avermitilis MA-4680 1213287 NP_822974.1 CDS SAV_1798 NC_003155.4 2194521 2195243 D PF01066: CDP-alcohol phosphatidyltransferase; hypothetical protein 2194521..2195243 Streptomyces avermitilis MA-4680 1213288 NP_822975.1 CDS fusA3 NC_003155.4 2195380 2197470 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2195380..2197470) Streptomyces avermitilis MA-4680 1213289 NP_822976.1 CDS SAV_1800 NC_003155.4 2197922 2199811 R PF00754: F5/8 type C domain; protein complement(2197922..2199811) Streptomyces avermitilis MA-4680 1213290 NP_822977.1 CDS bglC1 NC_003155.4 2200016 2201374 R beta-glucosidase complement(2200016..2201374) Streptomyces avermitilis MA-4680 1210285 NP_822978.1 CDS SAV_1802 NC_003155.4 2201404 2202276 R sugar ABC transporter permease complement(2201404..2202276) Streptomyces avermitilis MA-4680 1213291 NP_822979.1 CDS SAV_1803 NC_003155.4 2202269 2203267 R sugar ABC transporter permease complement(2202269..2203267) Streptomyces avermitilis MA-4680 1213292 NP_822980.1 CDS SAV_1804 NC_003155.4 2203282 2204598 R sugar ABC transporter substrate-binding protein complement(2203282..2204598) Streptomyces avermitilis MA-4680 1213293 NP_822981.1 CDS SAV_1805 NC_003155.4 2204780 2206078 D transcriptional regulator 2204780..2206078 Streptomyces avermitilis MA-4680 1213294 NP_822982.1 CDS SAV_1806 NC_003155.4 2206416 2208215 D protein 2206416..2208215 Streptomyces avermitilis MA-4680 1213295 NP_822983.1 CDS SAV_1807 NC_003155.4 2208269 2209414 R PF00877: NlpC/P60 family; hypothetical protein complement(2208269..2209414) Streptomyces avermitilis MA-4680 1213296 NP_822984.1 CDS sig18 NC_003155.4 2209514 2210155 R ECF subfamily RNA polymerase sigma factor complement(2209514..2210155) Streptomyces avermitilis MA-4680 1210286 NP_822985.1 CDS SAV_1809 NC_003155.4 2210275 2210961 R PF01427: D-ala-D-ala dipeptidase; dipeptidase complement(2210275..2210961) Streptomyces avermitilis MA-4680 1213297 NP_822986.1 CDS SAV_1810 NC_003155.4 2211087 2212124 R frameshift; regulatory protein complement(2211087..2212124) Streptomyces avermitilis MA-4680 1213298 NP_822987.1 CDS SAV_1811 NC_003155.4 2212064 2214322 R frameshift; regulatory protein complement(2212064..2214322) Streptomyces avermitilis MA-4680 1213299 NP_822988.1 CDS SAV_1812 NC_003155.4 2214722 2215747 D hypothetical protein 2214722..2215747 Streptomyces avermitilis MA-4680 1213300 NP_822989.1 CDS SAV_1813 NC_003155.4 2215992 2216453 D hypothetical protein 2215992..2216453 Streptomyces avermitilis MA-4680 1213301 NP_822990.1 CDS SAV_1814 NC_003155.4 2217271 2219466 R ATP/GTP-binding protein complement(2217271..2219466) Streptomyces avermitilis MA-4680 1213302 NP_822991.1 CDS SAV_1815 NC_003155.4 2220285 2222168 R ATP/GTP-binding protein complement(2220285..2222168) Streptomyces avermitilis MA-4680 1213303 NP_822992.1 CDS SAV_1816 NC_003155.4 2223614 2225155 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(2223614..2225155) Streptomyces avermitilis MA-4680 1213304 NP_822993.1 CDS sucD1 NC_003155.4 2225284 2226183 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(2225284..2226183) Streptomyces avermitilis MA-4680 1210288 NP_822994.1 CDS sucC NC_003155.4 2226195 2227325 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(2226195..2227325) Streptomyces avermitilis MA-4680 1210289 NP_822995.1 CDS ilvB3 NC_003155.4 2227504 2229198 D TPP-requiring enzyme (acetolactate synthase II) 2227504..2229198 Streptomyces avermitilis MA-4680 1210290 NP_822996.1 CDS SAV_1820 NC_003155.4 2229211 2230440 D catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2229211..2230440 Streptomyces avermitilis MA-4680 1213305 NP_822997.1 CDS acdA1 NC_003155.4 2230442 2232589 D acyl-CoA synthetase (NDP forming type) 2230442..2232589 Streptomyces avermitilis MA-4680 1213306 NP_822998.1 CDS SAV_1822 NC_003155.4 2232616 2234097 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 2232616..2234097 Streptomyces avermitilis MA-4680 1213307 NP_822999.1 CDS SAV_1823 NC_003155.4 2234099 2235505 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 2234099..2235505 Streptomyces avermitilis MA-4680 1213308 NP_823000.1 CDS SAV_1824 NC_003155.4 2235737 2236741 R DNA-binding protein complement(2235737..2236741) Streptomyces avermitilis MA-4680 1213309 NP_823001.1 CDS SAV_1825 NC_003155.4 2236754 2237962 R PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase complement(2236754..2237962) Streptomyces avermitilis MA-4680 1213310 NP_823002.1 CDS SAV_1826 NC_003155.4 2238014 2239063 R PF00532: Periplasmic binding proteins and sugar binding domain of the LacI family; solute binding protein complement(2238014..2239063) Streptomyces avermitilis MA-4680 1213311 NP_823003.1 CDS SAV_1827 NC_003155.4 2239081 2240100 R ABC transporter permease complement(2239081..2240100) Streptomyces avermitilis MA-4680 1213312 NP_823004.1 CDS SAV_1828 NC_003155.4 2240097 2241635 R ABC transporter ATP-binding protein complement(2240097..2241635) Streptomyces avermitilis MA-4680 1213313 NP_823005.1 CDS SAV_1829 NC_003155.4 2241772 2242962 R transcriptional regulator complement(2241772..2242962) Streptomyces avermitilis MA-4680 1213314 NP_823006.1 CDS SAV_1830 NC_003155.4 2243335 2244009 R GntR family transcriptional regulator complement(2243335..2244009) Streptomyces avermitilis MA-4680 1213315 NP_823007.1 CDS fabH2 NC_003155.4 2244160 2245107 R FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase III complement(2244160..2245107) Streptomyces avermitilis MA-4680 1210291 NP_823008.1 CDS SAV_1832 NC_003155.4 2245408 2246739 R PF07690: Major Facilitator Superfamily; integral membrane transporter complement(2245408..2246739) Streptomyces avermitilis MA-4680 1213316 NP_823009.1 CDS SAV_1833 NC_003155.4 2247042 2248013 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2247042..2248013 Streptomyces avermitilis MA-4680 1213317 NP_823010.1 CDS fdnG NC_003155.4 2248010 2249935 D PF00384: Molybdopterin oxidoreductase; formate dehydrogenase, major subunit (formate dehydrogenase alpha subunit) 2248010..2249935 Streptomyces avermitilis MA-4680 1213318 NP_823011.1 CDS nuoF2 NC_003155.4 2249944 2251767 D NADH dehydrogenase I chain F 2249944..2251767 Streptomyces avermitilis MA-4680 1210292 NP_823012.1 CDS nuoG2 NC_003155.4 2251764 2252624 D NADH dehydrogenase I chain G 2251764..2252624 Streptomyces avermitilis MA-4680 1210293 NP_823013.1 CDS fdhD NC_003155.4 2252632 2253480 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 2252632..2253480 Streptomyces avermitilis MA-4680 1210294 NP_823014.1 CDS dhbB NC_003155.4 2253602 2254159 R 2,3-dihydroxy-2,3-dihydrobenzoate synthase, PF00857: Isochorismatase family; isochorismatase complement(2253602..2254159) Streptomyces avermitilis MA-4680 1213319 NP_823015.1 CDS SAV_1839 NC_003155.4 2254179 2254613 R MarR family transcriptional regulator complement(2254179..2254613) Streptomyces avermitilis MA-4680 1213320 NP_823016.1 CDS SAV_1840 NC_003155.4 2254913 2255629 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 2254913..2255629 Streptomyces avermitilis MA-4680 1213321 NP_823017.1 CDS SAV_1841 NC_003155.4 2255652 2256032 D hypothetical protein 2255652..2256032 Streptomyces avermitilis MA-4680 1213322 NP_823018.1 CDS nanH NC_003155.4 2256926 2258803 D neuraminidase 2256926..2258803 Streptomyces avermitilis MA-4680 1210295 NP_823019.1 CDS SAV_1843 NC_003155.4 2258814 2260046 D hypothetical protein 2258814..2260046 Streptomyces avermitilis MA-4680 1213323 NP_823020.1 CDS SAV_1844 NC_003155.4 2259985 2261025 R PF01758: Sodium Bile acid symporter family; hypothetical protein complement(2259985..2261025) Streptomyces avermitilis MA-4680 1213324 NP_823021.1 CDS SAV_1845 NC_003155.4 2261159 2262028 D LysR family transcriptional regulator 2261159..2262028 Streptomyces avermitilis MA-4680 1213325 NP_823022.1 CDS SAV_1846 NC_003155.4 2262049 2263026 R transcription regulator AsnC complement(2262049..2263026) Streptomyces avermitilis MA-4680 1213326 NP_823023.1 CDS SAV_1847 NC_003155.4 2263141 2264625 D PF07690: Major Facilitator Superfamily; integral membrane efflux protein 2263141..2264625 Streptomyces avermitilis MA-4680 1213327 NP_823024.1 CDS fadD8 NC_003155.4 2264965 2266791 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase 2264965..2266791 Streptomyces avermitilis MA-4680 1210296 NP_823025.1 CDS SAV_1849 NC_003155.4 2267015 2267851 D PF00248: Aldo/keto reductase family; oxidoreductase 2267015..2267851 Streptomyces avermitilis MA-4680 1213328 NP_823026.1 CDS SAV_1850 NC_003155.4 2268155 2268856 D PF07335: Fungal chitosanase; protein 2268155..2268856 Streptomyces avermitilis MA-4680 1213329 NP_823027.1 CDS SAV_1851 NC_003155.4 2268934 2269635 R PF00106: short chain dehydrogenase; dehydrogenase complement(2268934..2269635) Streptomyces avermitilis MA-4680 1213330 NP_823028.1 CDS SAV_1852 NC_003155.4 2269812 2270690 R hypothetical protein complement(2269812..2270690) Streptomyces avermitilis MA-4680 1213331 NP_823029.1 CDS guxA2 NC_003155.4 2270907 2272616 R cellulose 1,4-beta-cellobiosidase complement(2270907..2272616) Streptomyces avermitilis MA-4680 1210297 NP_823030.1 CDS celA2 NC_003155.4 2272630 2274108 R endo-1,4-beta-glucanase complement(2272630..2274108) Streptomyces avermitilis MA-4680 1210298 NP_823031.1 CDS guxA3 NC_003155.4 2274373 2277294 D cellulose 1,4-beta-cellobiosidase 2274373..2277294 Streptomyces avermitilis MA-4680 1210299 NP_823032.1 CDS celA3 NC_003155.4 2277394 2280042 D endo-1,4-beta-glucanase 2277394..2280042 Streptomyces avermitilis MA-4680 1210300 NP_823033.1 CDS SAV_1857 NC_003155.4 2281132 2283006 R rhamnogalacturonan lyase complement(2281132..2283006) Streptomyces avermitilis MA-4680 1213332 NP_823034.1 CDS phhB NC_003155.4 2283348 2283653 R 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase complement(2283348..2283653) Streptomyces avermitilis MA-4680 1210301 NP_823035.1 CDS draG1 NC_003155.4 2283712 2284779 R ADP-ribosylglycohydrolase complement(2283712..2284779) Streptomyces avermitilis MA-4680 1210302 NP_823036.1 CDS SAV_1860 NC_003155.4 2284808 2285665 D DNA-binding protein 2284808..2285665 Streptomyces avermitilis MA-4680 1213333 NP_823037.1 CDS SAV_1861 NC_003155.4 2285819 2286682 D DNA-binding protein 2285819..2286682 Streptomyces avermitilis MA-4680 1213334 NP_823038.1 CDS SAV_1862 NC_003155.4 2286988 2287413 R ATP/GTP-binding protein complement(2286988..2287413) Streptomyces avermitilis MA-4680 1213335 NP_823039.1 CDS SAV_1863 NC_003155.4 2287656 2288348 D hypothetical protein 2287656..2288348 Streptomyces avermitilis MA-4680 1213336 NP_823040.1 CDS SAV_1864 NC_003155.4 2289461 2290849 D PF00092: von Willebrand factor type A domain; hypothetical protein 2289461..2290849 Streptomyces avermitilis MA-4680 1213337 NP_823041.1 CDS SAV_1865 NC_003155.4 2290934 2291254 R hypothetical protein complement(2290934..2291254) Streptomyces avermitilis MA-4680 1213338 NP_823042.1 CDS SAV_1866 NC_003155.4 2291726 2293855 R hypothetical protein complement(2291726..2293855) Streptomyces avermitilis MA-4680 1213339 NP_823043.1 CDS SAV_1867 NC_003155.4 2293994 2294419 R hypothetical protein complement(2293994..2294419) Streptomyces avermitilis MA-4680 1213340 NP_823044.1 CDS SAV_1868 NC_003155.4 2294521 2295288 D PF00753: Metallo-beta-lactamase superfamily; hypothetical protein 2294521..2295288 Streptomyces avermitilis MA-4680 1213341 NP_823045.1 CDS SAV_1869 NC_003155.4 2295335 2295958 D PF00597: DedA family; integral membrane protein 2295335..2295958 Streptomyces avermitilis MA-4680 1213342 NP_823046.1 CDS SAV_1870 NC_003155.4 2296065 2297234 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(2296065..2297234) Streptomyces avermitilis MA-4680 1213343 NP_823047.1 CDS SAV_1871 NC_003155.4 2297231 2298556 R hypothetical protein complement(2297231..2298556) Streptomyces avermitilis MA-4680 1213344 NP_823048.1 CDS SAV_1872 NC_003155.4 2298642 2299712 R hypothetical protein complement(2298642..2299712) Streptomyces avermitilis MA-4680 1213345 NP_823049.1 CDS sig19 NC_003155.4 2300101 2300895 R RNA polymerase alternative sigma factor; RNA polymerase sigma factor complement(2300101..2300895) Streptomyces avermitilis MA-4680 1210303 NP_823050.1 CDS SAV_1874 NC_003155.4 2301229 2301639 D hypothetical protein 2301229..2301639 Streptomyces avermitilis MA-4680 1213346 NP_823051.1 CDS SAV_1875 NC_003155.4 2301742 2302188 D PF00571: CBS domain; oxidoreductase 2301742..2302188 Streptomyces avermitilis MA-4680 1213347 NP_823052.1 CDS pfpI1 NC_003155.4 2302227 2302772 D PF01965: DJ-1/PfpI family; intracellular protease/amidase 2302227..2302772 Streptomyces avermitilis MA-4680 1213348 NP_823053.1 CDS SAV_1877 NC_003155.4 2302968 2303285 R hypothetical protein complement(2302968..2303285) Streptomyces avermitilis MA-4680 1213349 NP_823054.1 CDS SAV_1878 NC_003155.4 2303415 2305034 R ABC transporter ATP-binding protein complement(2303415..2305034) Streptomyces avermitilis MA-4680 1213350 NP_823055.1 CDS SAV_1879 NC_003155.4 2305147 2306640 D PF01569: PAP2 superfamily; hypothetical protein 2305147..2306640 Streptomyces avermitilis MA-4680 1213351 NP_823056.1 CDS SAV_1880 NC_003155.4 2306776 2307597 D UbiE family methyltransferase 2306776..2307597 Streptomyces avermitilis MA-4680 1213352 NP_823057.1 CDS gvpK2 NC_003155.4 2307611 2307895 R gas vesicle synthesis protein complement(2307611..2307895) Streptomyces avermitilis MA-4680 1210304 NP_823058.1 CDS gvpS2 NC_003155.4 2307892 2308086 R gas vesicle synthesis protein complement(2307892..2308086) Streptomyces avermitilis MA-4680 1210305 NP_823059.1 CDS gvpL2 NC_003155.4 2308083 2308850 R gas vesicle synthesis protein complement(2308083..2308850) Streptomyces avermitilis MA-4680 1210306 NP_823060.1 CDS gvpJ2 NC_003155.4 2308847 2309173 R gas vesicle synthesis protein complement(2308847..2309173) Streptomyces avermitilis MA-4680 1210307 NP_823061.1 CDS SAV_1885 NC_003155.4 2309170 2310306 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(2309170..2310306) Streptomyces avermitilis MA-4680 1213353 NP_823062.1 CDS SAV_1886 NC_003155.4 2310299 2310985 R hypothetical protein complement(2310299..2310985) Streptomyces avermitilis MA-4680 1213354 NP_823063.1 CDS gvpG2 NC_003155.4 2310982 2311245 R gas vesicle synthesis protein complement(2310982..2311245) Streptomyces avermitilis MA-4680 1210308 NP_823064.1 CDS gvpF2 NC_003155.4 2311286 2312053 R gas vesicle synthesis protein complement(2311286..2312053) Streptomyces avermitilis MA-4680 1210309 NP_823065.1 CDS gvpA2 NC_003155.4 2312050 2312475 R similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins; gas vesicle synthesis-like protein complement(2312050..2312475) Streptomyces avermitilis MA-4680 1210310 NP_823066.1 CDS gvpO2 NC_003155.4 2312532 2312879 R gas vesicle synthesis protein complement(2312532..2312879) Streptomyces avermitilis MA-4680 1210311 NP_823067.1 CDS tkt3 NC_003155.4 2313083 2314933 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(2313083..2314933) Streptomyces avermitilis MA-4680 1210312 NP_823068.1 CDS ndh1 NC_003155.4 2314930 2316291 R PF00070: Pyridine nucleotide-disulphide oxidoreductase; NADH dehydrogenase complement(2314930..2316291) Streptomyces avermitilis MA-4680 1213355 NP_823069.1 CDS SAV_1893 NC_003155.4 2316560 2317171 R PF07332: Protein of unknown function (DUF1469); hypothetical protein complement(2316560..2317171) Streptomyces avermitilis MA-4680 1213356 NP_823070.1 CDS SAV_1894 NC_003155.4 2317239 2317592 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 2317239..2317592 Streptomyces avermitilis MA-4680 1213357 NP_823071.1 CDS argI NC_003155.4 2317670 2318566 R arginase complement(2317670..2318566) Streptomyces avermitilis MA-4680 1213358 NP_823072.1 CDS SAV_1896 NC_003155.4 2318593 2319135 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(2318593..2319135) Streptomyces avermitilis MA-4680 1213359 NP_823073.1 CDS SAV_1897 NC_003155.4 2319187 2320119 R PF02016: LD-carboxypeptidase; carboxylpeptidase complement(2319187..2320119) Streptomyces avermitilis MA-4680 1213360 NP_823074.1 CDS SAV_1898 NC_003155.4 2320116 2322116 R PF00326: Prolyl oligopeptidase family; acyl-peptide hydrolase complement(2320116..2322116) Streptomyces avermitilis MA-4680 1213361 NP_823075.1 CDS SAV_1899 NC_003155.4 2322130 2323452 R PF01546: Peptidase family M20/M25/M40; hypothetical protein complement(2322130..2323452) Streptomyces avermitilis MA-4680 1213362 NP_823076.1 CDS SAV_1900 NC_003155.4 2323445 2324278 R PF04951: D-aminopeptidase; D-aminopeptidase complement(2323445..2324278) Streptomyces avermitilis MA-4680 1213363 NP_823077.1 CDS SAV_1901 NC_003155.4 2324383 2325108 R PF05724: Thiopurine S-methyltransferase (TPMT); hypothetical protein complement(2324383..2325108) Streptomyces avermitilis MA-4680 1213364 NP_823078.1 CDS SAV_1902 NC_003155.4 2325246 2327708 R PF07228: Stage II sporulation protein E (SpoIIE); hypothetical protein complement(2325246..2327708) Streptomyces avermitilis MA-4680 1213365 NP_823079.1 CDS SAV_1903 NC_003155.4 2327906 2330284 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(2327906..2330284) Streptomyces avermitilis MA-4680 1213366 NP_823080.1 CDS SAV_1904 NC_003155.4 2330438 2330881 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(2330438..2330881) Streptomyces avermitilis MA-4680 1213367 NP_823081.1 CDS SAV_1905 NC_003155.4 2331042 2332082 D PF04055: Radical SAM superfamily; hypothetical protein 2331042..2332082 Streptomyces avermitilis MA-4680 1213368 NP_823082.1 CDS SAV_1906 NC_003155.4 2332219 2333796 D PF00561: alpha/beta hydrolase fold; peptidase 2332219..2333796 Streptomyces avermitilis MA-4680 1213369 NP_823083.1 CDS SAV_1907 NC_003155.4 2333984 2334619 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 2333984..2334619 Streptomyces avermitilis MA-4680 1213370 NP_823084.1 CDS prpL2 NC_003155.4 2334531 2335139 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(2334531..2335139) Streptomyces avermitilis MA-4680 1213371 NP_823085.1 CDS fadC1 NC_003155.4 2335501 2337306 D PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase 2335501..2337306 Streptomyces avermitilis MA-4680 1210313 NP_823086.1 CDS SAV_1910 NC_003155.4 2337443 2338258 D TetR family transcriptional regulator 2337443..2338258 Streptomyces avermitilis MA-4680 1213372 NP_823087.1 CDS ccrA2 NC_003155.4 2338670 2340007 D crotonyl-CoA reductase 2338670..2340007 Streptomyces avermitilis MA-4680 1210314 NP_823088.1 CDS meaA1 NC_003155.4 2340018 2342066 D methylmalonyl-CoA mutase, coenzyme B12-dependent alpha subunit 2340018..2342066 Streptomyces avermitilis MA-4680 1210315 NP_823089.1 CDS citE2 NC_003155.4 2342063 2343028 D citrate lyase beta chain 2342063..2343028 Streptomyces avermitilis MA-4680 1213373 NP_823090.1 CDS SAV_1914 NC_003155.4 2343034 2343561 D PF01575: MaoC like domain; hypothetical protein 2343034..2343561 Streptomyces avermitilis MA-4680 1213374 NP_823091.1 CDS fadE5 NC_003155.4 2343564 2344769 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 2343564..2344769 Streptomyces avermitilis MA-4680 1210316 NP_823092.1 CDS psd NC_003155.4 2344940 2345587 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 2344940..2345587 Streptomyces avermitilis MA-4680 1213375 NP_823093.1 CDS pssA NC_003155.4 2345646 2346428 D PF01066: CDP-alcohol phosphatidyltransferase; phosphatidylserine synthase 2345646..2346428 Streptomyces avermitilis MA-4680 1210317 NP_823094.1 CDS glxK NC_003155.4 2346527 2347678 R glycerate kinase complement(2346527..2347678) Streptomyces avermitilis MA-4680 1213376 NP_823095.1 CDS SAV_1919 NC_003155.4 2347825 2348958 D PF03747: ADP-ribosylglycohydrolase; hypothetical protein 2347825..2348958 Streptomyces avermitilis MA-4680 1213377 NP_823096.1 CDS SAV_1920 NC_003155.4 2349134 2349628 D PF00293: NUDIX domain; hypothetical protein 2349134..2349628 Streptomyces avermitilis MA-4680 1213378 NP_823097.1 CDS SAV_1921 NC_003155.4 2350196 2350636 D integral membrane protein 2350196..2350636 Streptomyces avermitilis MA-4680 1213379 NP_823098.1 CDS gdh NC_003155.4 2350818 2351657 D glucose 1-dehydrogenase 2350818..2351657 Streptomyces avermitilis MA-4680 1210318 NP_823099.1 CDS cydA2 NC_003155.4 2352169 2353203 D frameshift; cytochrome bd-I oxidase subunit I 2352169..2353203 Streptomyces avermitilis MA-4680 1210319 NP_823100.1 CDS cydB2 NC_003155.4 2353200 2354249 D cytochrome bd-I oxidase subunit II 2353200..2354249 Streptomyces avermitilis MA-4680 1210320 NP_823101.1 CDS gntK1 NC_003155.4 2354246 2354812 D gluconokinase 2354246..2354812 Streptomyces avermitilis MA-4680 1213380 NP_823102.1 CDS SAV_1926 NC_003155.4 2354964 2355419 R PF01839: FG-GAP repeat; hypothetical protein complement(2354964..2355419) Streptomyces avermitilis MA-4680 1213381 NP_823103.1 CDS SAV_1927 NC_003155.4 2355609 2356976 D integral membrane protein 2355609..2356976 Streptomyces avermitilis MA-4680 1213382 NP_823104.1 CDS SAV_1928 NC_003155.4 2356960 2357916 R PF04087: Domain of unknown function (DUF389); integral membrane protein complement(2356960..2357916) Streptomyces avermitilis MA-4680 1213383 NP_823105.1 CDS SAV_1929 NC_003155.4 2358051 2358983 D PF04199: Putative cyclase; cyclase 2358051..2358983 Streptomyces avermitilis MA-4680 1213384 NP_823106.1 CDS chd NC_003155.4 2359062 2360699 D PF00732: GMC oxidoreductase; choline dehydrogenase 2359062..2360699 Streptomyces avermitilis MA-4680 1213385 NP_823107.1 CDS SAV_1931 NC_003155.4 2360696 2362114 D hypothetical protein 2360696..2362114 Streptomyces avermitilis MA-4680 1213386 NP_823108.1 CDS SAV_1932 NC_003155.4 2362140 2363957 D PF00723: Glycosyl hydrolases family 15; glycosyl hydrolase 2362140..2363957 Streptomyces avermitilis MA-4680 1213387 NP_823109.1 CDS ogt1 NC_003155.4 2363976 2364458 R methylated-DNA--protein-cysteine S-methyltransferase complement(2363976..2364458) Streptomyces avermitilis MA-4680 1210321 NP_823110.1 CDS alkA1 NC_003155.4 2364468 2365934 R PF06029: AlkA N-terminal domain; ADA-like regulatory protein complement(2364468..2365934) Streptomyces avermitilis MA-4680 1210322 NP_823111.1 CDS SAV_1935 NC_003155.4 2366193 2367722 R PF00355: Rieske [2Fe-2S] domain; iron-sulfur binding oxidoreductase complement(2366193..2367722) Streptomyces avermitilis MA-4680 1213388 NP_823112.1 CDS SAV_1936 NC_003155.4 2368372 2369790 R PF01593: Flavin containing amine oxidoreductase; dehydrogenase complement(2368372..2369790) Streptomyces avermitilis MA-4680 1213389 NP_823113.1 CDS SAV_1937 NC_003155.4 2369954 2370799 R PF00459: Inositol monophosphatase family; inositol monophosphatase complement(2369954..2370799) Streptomyces avermitilis MA-4680 1213390 NP_823114.1 CDS ggt1 NC_003155.4 2370885 2372822 R PF01019: Gamma-glutamyltranspeptidase; gamma-glutamyltranspeptidase complement(2370885..2372822) Streptomyces avermitilis MA-4680 1213391 NP_823115.1 CDS SAV_1939 NC_003155.4 2373040 2373903 D hypothetical protein 2373040..2373903 Streptomyces avermitilis MA-4680 1213392 NP_823116.1 CDS SAV_1940 NC_003155.4 2373980 2374411 R hypothetical protein complement(2373980..2374411) Streptomyces avermitilis MA-4680 1213393 NP_823117.1 CDS fdh NC_003155.4 2374703 2375866 R Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase complement(2374703..2375866) Streptomyces avermitilis MA-4680 1213394 NP_823118.1 CDS ccrB NC_003155.4 2376076 2376690 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 2376076..2376690 Streptomyces avermitilis MA-4680 1213395 YP_001621482.1 CDS crcB4 NC_003155.4 2376687 2377058 D putative camphor resistance protein CrcB 2376687..2377058 Streptomyces avermitilis MA-4680 5815323 NP_823119.1 CDS SAV_1943 NC_003155.4 2377711 2378349 D amidate substrates transporter protein 2377711..2378349 Streptomyces avermitilis MA-4680 1213396 NP_823120.1 CDS SAV_1944 NC_003155.4 2378374 2379624 D acetamidase 2378374..2379624 Streptomyces avermitilis MA-4680 1213397 NP_823121.1 CDS SAV_1945 NC_003155.4 2379723 2380619 R hypothetical protein complement(2379723..2380619) Streptomyces avermitilis MA-4680 1213398 NP_823122.1 CDS SAV_1946 NC_003155.4 2380833 2381501 D hypothetical protein 2380833..2381501 Streptomyces avermitilis MA-4680 1213399 NP_823123.1 CDS SAV_1947 NC_003155.4 2381561 2383102 R allantoin permease complement(2381561..2383102) Streptomyces avermitilis MA-4680 1213400 NP_823124.1 CDS SAV_1948 NC_003155.4 2383259 2384284 R N5,N10-methylene- tetrahydromethanopterin reductase complement(2383259..2384284) Streptomyces avermitilis MA-4680 1213401 NP_823125.1 CDS dht NC_003155.4 2384296 2385696 R catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase complement(2384296..2385696) Streptomyces avermitilis MA-4680 1213402 NP_823126.1 CDS SAV_1950 NC_003155.4 2385800 2386642 R PF00795: Carbon-nitrogen hydrolase; hydrolase complement(2385800..2386642) Streptomyces avermitilis MA-4680 1213403 NP_823127.1 CDS SAV_1951 NC_003155.4 2386791 2388350 R regulatory protein complement(2386791..2388350) Streptomyces avermitilis MA-4680 1213404 NP_823128.1 CDS SAV_1952 NC_003155.4 2388408 2389688 R aminotransferase complement(2388408..2389688) Streptomyces avermitilis MA-4680 1213405 NP_823129.1 CDS SAV_1953 NC_003155.4 2389685 2390527 R PF00795: Carbon-nitrogen hydrolase; hydrolase complement(2389685..2390527) Streptomyces avermitilis MA-4680 1213406 NP_823130.1 CDS SAV_1954 NC_003155.4 2390738 2392417 R PF01391: Collagen triple helix repeat (20 copies); hypothetical protein complement(2390738..2392417) Streptomyces avermitilis MA-4680 1213407 NP_823131.1 CDS SAV_1955 NC_003155.4 2392503 2392760 R DNA-binding protein complement(2392503..2392760) Streptomyces avermitilis MA-4680 1213408 NP_823132.1 CDS map1 NC_003155.4 2392839 2393624 D PF00557: metallopeptidase family M24; methionine aminopeptidase 2392839..2393624 Streptomyces avermitilis MA-4680 1213409 NP_823133.1 CDS ggt2 NC_003155.4 2393820 2395619 R PF01019: Gamma-glutamyltranspeptidase; gamma-glutamyltranspeptidase complement(2393820..2395619) Streptomyces avermitilis MA-4680 1210323 NP_823134.1 CDS SAV_1958 NC_003155.4 2395725 2396480 D protein 2395725..2396480 Streptomyces avermitilis MA-4680 1213410 NP_823135.1 CDS SAV_1959 NC_003155.4 2396597 2398165 D PF02129: X-Pro dipeptidyl-peptidase (S15 family); acyl esterase 2396597..2398165 Streptomyces avermitilis MA-4680 1213411 NP_823136.1 CDS gluD1 NC_003155.4 2398214 2399104 R ABC transporter permease; glutamate transporter permease complement(2398214..2399104) Streptomyces avermitilis MA-4680 1210324 NP_823137.1 CDS gluC1 NC_003155.4 2399101 2399745 R ABC transporter permease; glutamate transporter permease complement(2399101..2399745) Streptomyces avermitilis MA-4680 1210325 NP_823138.1 CDS gluB1 NC_003155.4 2399757 2400674 R ABC transporter substrate-binding protein; glutamate binding periplasmic protein complement(2399757..2400674) Streptomyces avermitilis MA-4680 1210326 NP_823139.1 CDS gluA1 NC_003155.4 2400693 2401454 R ABC transporter ATP-binding protein; glutamate uptake system ATP-binding protein complement(2400693..2401454) Streptomyces avermitilis MA-4680 1210327 NP_823140.1 CDS SAV_1964 NC_003155.4 2401552 2401992 R hypothetical protein complement(2401552..2401992) Streptomyces avermitilis MA-4680 1213412 NP_823141.1 CDS SAV_1965 NC_003155.4 2402200 2403963 D PF00657: GDSL-like Lipase/Acylhydrolase; protein 2402200..2403963 Streptomyces avermitilis MA-4680 1213413 NP_823142.1 CDS xthA NC_003155.4 2403970 2404758 R exonuclease complement(2403970..2404758) Streptomyces avermitilis MA-4680 1210328 NP_823143.1 CDS SAV_1967 NC_003155.4 2404839 2405474 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(2404839..2405474) Streptomyces avermitilis MA-4680 1213414 NP_823144.1 CDS pcaL2 NC_003155.4 2405547 2406842 R PF02627: Carboxymuconolactone decarboxylase family; 3-oxoadipate enol-lactone hydrolase complement(2405547..2406842) Streptomyces avermitilis MA-4680 1213415 NP_823145.1 CDS SAV_1969 NC_003155.4 2406875 2407447 R IS110 family; IS110 family transposase complement(2406875..2407447) Streptomyces avermitilis MA-4680 1213416 NP_823146.1 CDS SAV_1970 NC_003155.4 2407717 2408478 R PF00106: short chain dehydrogenase; dehydrogenase complement(2407717..2408478) Streptomyces avermitilis MA-4680 1213417 NP_823147.1 CDS SAV_1971 NC_003155.4 2408669 2409541 D DNA-binding protein 2408669..2409541 Streptomyces avermitilis MA-4680 1213418 NP_823148.1 CDS SAV_1972 NC_003155.4 2409621 2409863 R hypothetical protein complement(2409621..2409863) Streptomyces avermitilis MA-4680 1213419 NP_823149.1 CDS SAV_1973 NC_003155.4 2410108 2410929 R PF00561: alpha/beta hydrolase fold; hydrolase complement(2410108..2410929) Streptomyces avermitilis MA-4680 1213420 NP_823150.1 CDS map2 NC_003155.4 2411322 2412089 R PF00557: metallopeptidase family M24; methionine aminopeptidase complement(2411322..2412089) Streptomyces avermitilis MA-4680 1213421 NP_823151.1 CDS SAV_1975 NC_003155.4 2412155 2412460 D DNA-binding protein 2412155..2412460 Streptomyces avermitilis MA-4680 1213422 NP_823152.1 CDS SAV_1976 NC_003155.4 2412485 2412787 R hypothetical protein complement(2412485..2412787) Streptomyces avermitilis MA-4680 1213423 NP_823153.1 CDS SAV_1977 NC_003155.4 2413020 2415392 R PF04434: SWIM zinc finger; hypothetical protein complement(2413020..2415392) Streptomyces avermitilis MA-4680 1213424 NP_823154.1 CDS helZ3 NC_003155.4 2415389 2418277 R SNF2/RAD54 family helicase complement(2415389..2418277) Streptomyces avermitilis MA-4680 1210329 NP_823155.1 CDS SAV_1979 NC_003155.4 2418373 2418957 R hypothetical protein complement(2418373..2418957) Streptomyces avermitilis MA-4680 1213425 NP_823156.1 CDS SAV_1980 NC_003155.4 2418954 2420099 R sugar kinase complement(2418954..2420099) Streptomyces avermitilis MA-4680 1213426 NP_823157.1 CDS SAV_1981 NC_003155.4 2420149 2420991 R sugar ABC transporter ATP-binding protein complement(2420149..2420991) Streptomyces avermitilis MA-4680 1213427 NP_823158.1 CDS SAV_1982 NC_003155.4 2420988 2422019 R sugar ABC transporter permease complement(2420988..2422019) Streptomyces avermitilis MA-4680 1213428 NP_823159.1 CDS SAV_1983 NC_003155.4 2422016 2423020 R sugar ABC substrate-bindig protein complement(2422016..2423020) Streptomyces avermitilis MA-4680 1213429 NP_823160.1 CDS SAV_1984 NC_003155.4 2423172 2423921 R PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator complement(2423172..2423921) Streptomyces avermitilis MA-4680 1213430 NP_823161.1 CDS SAV_1985 NC_003155.4 2424038 2425048 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 2424038..2425048 Streptomyces avermitilis MA-4680 1213431 NP_823162.1 CDS paaI NC_003155.4 2425067 2425492 R phenylacetic acid degradation protein complement(2425067..2425492) Streptomyces avermitilis MA-4680 1210330 NP_823163.1 CDS cyp8 NC_003155.4 2425563 2426744 R CYP107L2, adjacent to paaI; cytochrome P450 hydroxylase complement(2425563..2426744) Streptomyces avermitilis MA-4680 1210331 NP_823164.1 CDS SAV_1988 NC_003155.4 2426786 2427457 R two-component system response regulator complement(2426786..2427457) Streptomyces avermitilis MA-4680 1213432 NP_823165.1 CDS SAV_1989 NC_003155.4 2427604 2428632 D similar to norsolorinic acid reductase, PF00248: Aldo/keto reductase family; aryl-alcohol dehydrogenase 2427604..2428632 Streptomyces avermitilis MA-4680 1213433 NP_823166.1 CDS SAV_1990 NC_003155.4 2428735 2430174 R two-component system sensor kinase complement(2428735..2430174) Streptomyces avermitilis MA-4680 1213434 NP_823167.1 CDS SAV_1991 NC_003155.4 2430390 2430785 R PF00545: ribonuclease; guanyl-specific ribonuclease Sa3 precursor (RNase Sa3) complement(2430390..2430785) Streptomyces avermitilis MA-4680 1213435 NP_823168.1 CDS SAV_1992 NC_003155.4 2430872 2431777 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(2430872..2431777) Streptomyces avermitilis MA-4680 1213436 NP_823169.1 CDS SAV_1993 NC_003155.4 2431903 2432511 R PF01872: RibD C-terminal domain; hypothetical protein complement(2431903..2432511) Streptomyces avermitilis MA-4680 1213437 NP_823170.1 CDS SAV_1994 NC_003155.4 2432709 2433716 D cation transporter 2432709..2433716 Streptomyces avermitilis MA-4680 1213438 NP_823171.1 CDS SAV_1995 NC_003155.4 2433754 2434884 R catalyzes the formation of S-ureidoglycolate and urea from allantoate; allantoicase complement(2433754..2434884) Streptomyces avermitilis MA-4680 1213439 NP_823172.1 CDS pucH NC_003155.4 2434954 2436291 R allantoinase complement(2434954..2436291) Streptomyces avermitilis MA-4680 1210332 NP_823173.1 CDS SAV_1997 NC_003155.4 2436542 2437345 D IclR family transcriptional regulator 2436542..2437345 Streptomyces avermitilis MA-4680 1213440 NP_823174.1 CDS SAV_1998 NC_003155.4 2437674 2438168 R hypothetical protein complement(2437674..2438168) Streptomyces avermitilis MA-4680 1213441 NP_823175.1 CDS SAV_1999 NC_003155.4 2438198 2438797 D hypothetical protein 2438198..2438797 Streptomyces avermitilis MA-4680 1213442 NP_823176.1 CDS aceB1 NC_003155.4 2439019 2440644 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 2439019..2440644 Streptomyces avermitilis MA-4680 1210333 NP_823177.1 CDS SAV_2001 NC_003155.4 2440649 2440948 R PF05169: Selenoprotein W-related family; hypothetical protein complement(2440649..2440948) Streptomyces avermitilis MA-4680 1213443 NP_823178.1 CDS SAV_2002 NC_003155.4 2440927 2441841 R hypothetical protein complement(2440927..2441841) Streptomyces avermitilis MA-4680 1213444 NP_823179.1 CDS SAV_2003 NC_003155.4 2441883 2443400 R iron transport protein complement(2441883..2443400) Streptomyces avermitilis MA-4680 1213445 NP_823180.1 CDS SAV_2004 NC_003155.4 2443486 2444994 D iron transport protein 2443486..2444994 Streptomyces avermitilis MA-4680 1213446 NP_823181.1 CDS SAV_2005 NC_003155.4 2445049 2446311 D PF00092: von Willebrand factor type A domain; hypothetical protein 2445049..2446311 Streptomyces avermitilis MA-4680 1213447 NP_823182.1 CDS SAV_2006 NC_003155.4 2446311 2447156 D hypothetical protein 2446311..2447156 Streptomyces avermitilis MA-4680 1213448 NP_823183.1 CDS SAV_2007 NC_003155.4 2447531 2448187 R transcriptional regulator complement(2447531..2448187) Streptomyces avermitilis MA-4680 1213449 NP_823184.1 CDS aspB1 NC_003155.4 2448255 2449463 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2448255..2449463 Streptomyces avermitilis MA-4680 1213450 NP_823185.1 CDS SAV_2009 NC_003155.4 2449575 2450174 D mutase 2449575..2450174 Streptomyces avermitilis MA-4680 1213451 NP_823186.1 CDS SAV_2010 NC_003155.4 2450191 2450817 R hypothetical protein complement(2450191..2450817) Streptomyces avermitilis MA-4680 1213452 NP_823187.1 CDS SAV_2011 NC_003155.4 2450999 2451421 D PF03061: Thioesterase superfamily; hypothetical protein 2450999..2451421 Streptomyces avermitilis MA-4680 1213453 NP_823188.1 CDS SAV_2012 NC_003155.4 2451474 2451875 R PF01638: Transcriptional regulator; transcriptional regulator complement(2451474..2451875) Streptomyces avermitilis MA-4680 1213454 NP_823189.1 CDS SAV_2013 NC_003155.4 2451977 2453437 D PF07690: Major Facilitator Superfamily; transport integral membrane protein 2451977..2453437 Streptomyces avermitilis MA-4680 1213455 NP_823190.1 CDS SAV_2014 NC_003155.4 2453633 2455819 D alpha-N-acetylglucosaminidase 2453633..2455819 Streptomyces avermitilis MA-4680 1213456 NP_823191.1 CDS csn1 NC_003155.4 2455947 2456762 D PF01374: Glycosyl hydrolase family 46; chitosanase 2455947..2456762 Streptomyces avermitilis MA-4680 1213457 NP_823192.1 CDS pbuX2 NC_003155.4 2456869 2458329 R xanthine/uracil permease complement(2456869..2458329) Streptomyces avermitilis MA-4680 1213458 NP_823193.1 CDS SAV_2017 NC_003155.4 2458527 2459906 R catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.; hydroxydechloroatrazine ethylaminohydrolase complement(2458527..2459906) Streptomyces avermitilis MA-4680 1213459 NP_823194.1 CDS pucL NC_003155.4 2460041 2460988 R uricase complement(2460041..2460988) Streptomyces avermitilis MA-4680 1210334 NP_823195.1 CDS SAV_2019 NC_003155.4 2460995 2461402 R PF00576: Transthyretin precursor (formerly prealbumin); hypothetical protein complement(2460995..2461402) Streptomyces avermitilis MA-4680 1213460 NP_823196.1 CDS SAV_2020 NC_003155.4 2461399 2461917 R putative OHCU decarboxylase complement(2461399..2461917) Streptomyces avermitilis MA-4680 1213461 NP_823197.1 CDS SAV_2021 NC_003155.4 2462114 2462482 R DNA-binding protein complement(2462114..2462482) Streptomyces avermitilis MA-4680 1213462 NP_823198.1 CDS SAV_2022 NC_003155.4 2462479 2462730 R hypothetical protein complement(2462479..2462730) Streptomyces avermitilis MA-4680 1213463 NP_823199.1 CDS SAV_2023 NC_003155.4 2463053 2464564 D hypothetical protein 2463053..2464564 Streptomyces avermitilis MA-4680 1213464 NP_823200.1 CDS gip NC_003155.4 2464761 2465618 D hydroxypyruvate isomerase 2464761..2465618 Streptomyces avermitilis MA-4680 1213465 NP_823201.1 CDS garR NC_003155.4 2465738 2466655 D PF03446: NAD binding domain of 6-phosphogluconate dehydrogenase; 2-hydroxy-3-oxopropionate reductase 2465738..2466655 Streptomyces avermitilis MA-4680 1213466 NP_823202.1 CDS katA3 NC_003155.4 2466817 2468274 D catalase 2466817..2468274 Streptomyces avermitilis MA-4680 1210335 NP_823203.1 CDS SAV_2027 NC_003155.4 2468588 2468824 D hypothetical protein 2468588..2468824 Streptomyces avermitilis MA-4680 1213467 NP_823204.1 CDS gcl NC_003155.4 2469196 2470980 R catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase complement(2469196..2470980) Streptomyces avermitilis MA-4680 1213468 NP_823205.1 CDS SAV_2029 NC_003155.4 2471145 2472263 D hypothetical protein 2471145..2472263 Streptomyces avermitilis MA-4680 1213469 NP_823206.1 CDS SAV_2030 NC_003155.4 2472283 2473905 R activates fatty acids by binding to coenzyme A; AMP-binding domain protein complement(2472283..2473905) Streptomyces avermitilis MA-4680 1213470 NP_823207.1 CDS acsA4 NC_003155.4 2473902 2475581 R acetyl-CoA synthetase complement(2473902..2475581) Streptomyces avermitilis MA-4680 1210336 NP_823208.1 CDS SAV_2032 NC_003155.4 2475684 2476523 D LuxR family transcriptional regulator 2475684..2476523 Streptomyces avermitilis MA-4680 1213471 NP_823209.1 CDS SAV_2033 NC_003155.4 2476757 2479567 D LuxR family transcriptional regulator 2476757..2479567 Streptomyces avermitilis MA-4680 1213472 NP_823210.1 CDS SAV_2034 NC_003155.4 2480500 2481291 D PF00089: Trypsin; trypsin-like protease 2480500..2481291 Streptomyces avermitilis MA-4680 1213473 NP_823211.1 CDS SAV_2035 NC_003155.4 2481442 2482710 R hypothetical protein complement(2481442..2482710) Streptomyces avermitilis MA-4680 1213474 NP_823212.1 CDS SAV_2036 NC_003155.4 2482828 2483988 D metal-transport protein 2482828..2483988 Streptomyces avermitilis MA-4680 1213475 NP_823213.1 CDS SAV_2037 NC_003155.4 2484187 2484477 R hypothetical protein complement(2484187..2484477) Streptomyces avermitilis MA-4680 1213476 NP_823214.1 CDS SAV_2038 NC_003155.4 2484587 2484862 R hypothetical protein complement(2484587..2484862) Streptomyces avermitilis MA-4680 1213477 NP_823215.1 CDS mcmB NC_003155.4 2485130 2486941 D methylmalonyl-CoA mutase subunit beta 2485130..2486941 Streptomyces avermitilis MA-4680 1210337 NP_823216.1 CDS meaA2 NC_003155.4 2486941 2489115 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 2486941..2489115 Streptomyces avermitilis MA-4680 1210338 NP_823217.1 CDS argK1 NC_003155.4 2489130 2490116 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 2489130..2490116 Streptomyces avermitilis MA-4680 1213478 NP_823218.1 CDS SAV_2042 NC_003155.4 2490199 2491605 R DNA-binding protein complement(2490199..2491605) Streptomyces avermitilis MA-4680 1213479 NP_823219.1 CDS aceA NC_003155.4 2491982 2493265 D Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 2491982..2493265 Streptomyces avermitilis MA-4680 1210339 NP_823220.1 CDS aceB2 NC_003155.4 2493411 2495003 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 2493411..2495003 Streptomyces avermitilis MA-4680 1213480 NP_823221.1 CDS fadC2 NC_003155.4 2495000 2495869 D converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 2495000..2495869 Streptomyces avermitilis MA-4680 1210340 NP_823222.1 CDS metE NC_003155.4 2496389 2498707 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 2496389..2498707 Streptomyces avermitilis MA-4680 1210341 NP_823223.1 CDS SAV_2047 NC_003155.4 2498826 2499458 D PF00300: Phosphoglycerate mutase family; hypothetical protein 2498826..2499458 Streptomyces avermitilis MA-4680 1213481 NP_823224.1 CDS SAV_2048 NC_003155.4 2499563 2499997 R hypothetical protein complement(2499563..2499997) Streptomyces avermitilis MA-4680 1213482 NP_823225.1 CDS SAV_2049 NC_003155.4 2500177 2500935 R hypothetical protein complement(2500177..2500935) Streptomyces avermitilis MA-4680 1213483 NP_823226.1 CDS SAV_2050 NC_003155.4 2500955 2501176 R hypothetical protein complement(2500955..2501176) Streptomyces avermitilis MA-4680 1213484 NP_823227.1 CDS SAV_2051 NC_003155.4 2501322 2501942 R PF00144: Beta-lactamase; hydrolase complement(2501322..2501942) Streptomyces avermitilis MA-4680 1213485 NP_823228.1 CDS SAV_2052 NC_003155.4 2502254 2503138 D PF04138: GtrA-like protein; hypothetical protein 2502254..2503138 Streptomyces avermitilis MA-4680 1213486 NP_823229.1 CDS ogt2 NC_003155.4 2503388 2503894 D methylated-DNA--protein-cysteine S-methyltransferase 2503388..2503894 Streptomyces avermitilis MA-4680 1210342 NP_823230.1 CDS SAV_2054 NC_003155.4 2504022 2504753 D hypothetical protein 2504022..2504753 Streptomyces avermitilis MA-4680 1213487 NP_823231.1 CDS SAV_2055 NC_003155.4 2504984 2505988 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(2504984..2505988) Streptomyces avermitilis MA-4680 1213488 NP_823232.1 CDS SAV_2056 NC_003155.4 2506218 2506607 D TetR family transcriptional regulator 2506218..2506607 Streptomyces avermitilis MA-4680 1213489 NP_823233.1 CDS SAV_2057 NC_003155.4 2506932 2507261 R hypothetical protein complement(2506932..2507261) Streptomyces avermitilis MA-4680 1213490 NP_823234.1 CDS SAV_2058 NC_003155.4 2507392 2508177 D PF03861: ANTAR domain; hypothetical protein 2507392..2508177 Streptomyces avermitilis MA-4680 1213491 NP_823235.1 CDS SAV_2059 NC_003155.4 2508252 2509550 R two-component system sensor kinase complement(2508252..2509550) Streptomyces avermitilis MA-4680 1213492 NP_823236.1 CDS SAV_2060 NC_003155.4 2509863 2510627 D deacetylase 2509863..2510627 Streptomyces avermitilis MA-4680 1213493 NP_823237.1 CDS cyp9 NC_003155.4 2510664 2511890 R CYP179A1; cytochrome P450 complement(2510664..2511890) Streptomyces avermitilis MA-4680 1210343 NP_823238.1 CDS SAV_2062 NC_003155.4 2512000 2513007 R hypothetical protein complement(2512000..2513007) Streptomyces avermitilis MA-4680 1213494 NP_823239.1 CDS SAV_2063 NC_003155.4 2513146 2513595 D PF03364: Streptomyces cyclase/dehydrase; hypothetical protein 2513146..2513595 Streptomyces avermitilis MA-4680 1213495 NP_823240.1 CDS SAV_2064 NC_003155.4 2513783 2514493 D methyltransferase 2513783..2514493 Streptomyces avermitilis MA-4680 1213496 NP_823241.1 CDS SAV_2065 NC_003155.4 2514502 2515653 R PF02625: XdhC and CoxI family; hypothetical protein complement(2514502..2515653) Streptomyces avermitilis MA-4680 1213497 NP_823242.1 CDS SAV_2066 NC_003155.4 2515726 2517183 R permease complement(2515726..2517183) Streptomyces avermitilis MA-4680 1213498 NP_823243.1 CDS pucB NC_003155.4 2517348 2519729 R xanthine dehydrogenase complement(2517348..2519729) Streptomyces avermitilis MA-4680 1210344 NP_823244.1 CDS SAV_2068 NC_003155.4 2519732 2520322 R PF01799: [2Fe-2S] binding domain; oxidoreductase complement(2519732..2520322) Streptomyces avermitilis MA-4680 1213499 NP_823245.1 CDS SAV_2069 NC_003155.4 2520322 2521221 R PF00941: FAD binding domain in molybdopterin dehydrogenase; dehydrogenase complement(2520322..2521221) Streptomyces avermitilis MA-4680 1213500 NP_823246.1 CDS SAV_2070 NC_003155.4 2521609 2523282 D regulatory protein 2521609..2523282 Streptomyces avermitilis MA-4680 1213501 NP_823247.1 CDS SAV_2071 NC_003155.4 2523435 2524208 D hypothetical protein 2523435..2524208 Streptomyces avermitilis MA-4680 1213502 NP_823248.1 CDS SAV_2072 NC_003155.4 2524283 2524564 R hypothetical protein complement(2524283..2524564) Streptomyces avermitilis MA-4680 1213503 NP_823249.1 CDS SAV_2073 NC_003155.4 2524698 2525588 R GntR family transcriptional regulator complement(2524698..2525588) Streptomyces avermitilis MA-4680 1213504 NP_823250.1 CDS SAV_2074 NC_003155.4 2525772 2526599 D hypothetical protein 2525772..2526599 Streptomyces avermitilis MA-4680 1213505 NP_823251.1 CDS SAV_2075 NC_003155.4 2526922 2527974 D hypothetical protein 2526922..2527974 Streptomyces avermitilis MA-4680 1213506 NP_823252.1 CDS SAV_2076 NC_003155.4 2528041 2528463 R regulatory protein complement(2528041..2528463) Streptomyces avermitilis MA-4680 1213507 NP_823253.1 CDS SAV_2077 NC_003155.4 2529077 2529568 R hypothetical protein complement(2529077..2529568) Streptomyces avermitilis MA-4680 1213508 NP_823254.1 CDS SAV_2078 NC_003155.4 2529637 2530509 R hypothetical protein complement(2529637..2530509) Streptomyces avermitilis MA-4680 1213509 NP_823255.1 CDS poxB2 NC_003155.4 2530721 2532463 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(2530721..2532463) Streptomyces avermitilis MA-4680 1213510 NP_823256.1 CDS SAV_2080 NC_003155.4 2532518 2534542 R hypothetical protein complement(2532518..2534542) Streptomyces avermitilis MA-4680 1213511 NP_823257.1 CDS SAV_2081 NC_003155.4 2535097 2536080 D LuxR family transcriptional regulator 2535097..2536080 Streptomyces avermitilis MA-4680 1213512 NP_823258.1 CDS SAV_2082 NC_003155.4 2536117 2536599 D hypothetical protein 2536117..2536599 Streptomyces avermitilis MA-4680 1213513 NP_823259.1 CDS SAV_2083 NC_003155.4 2536749 2538014 R PF00657: GDSL-like Lipase/Acylhydrolase; protein complement(2536749..2538014) Streptomyces avermitilis MA-4680 1213514 NP_823260.1 CDS SAV_2084 NC_003155.4 2538106 2538507 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 2538106..2538507 Streptomyces avermitilis MA-4680 1213515 NP_823261.1 CDS alkA2 NC_003155.4 2538571 2539989 R PF06029: AlkA N-terminal domain; ADA-like regulatory protein complement(2538571..2539989) Streptomyces avermitilis MA-4680 1210345 NP_823262.1 CDS SAV_2086 NC_003155.4 2540161 2541288 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(2540161..2541288) Streptomyces avermitilis MA-4680 1213516 NP_823263.1 CDS SAV_2087 NC_003155.4 2543124 2544659 R cellulose-binding protein complement(2543124..2544659) Streptomyces avermitilis MA-4680 1213517 NP_823264.1 CDS SAV_2088 NC_003155.4 2545065 2546384 R PF04055: Radical SAM superfamily; hypothetical protein complement(2545065..2546384) Streptomyces avermitilis MA-4680 1213518 NP_823265.1 CDS SAV_2089 NC_003155.4 2546610 2547617 R PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; 2-hydroxyacid dehydrogenase complement(2546610..2547617) Streptomyces avermitilis MA-4680 1213519 NP_823266.1 CDS SAV_2090 NC_003155.4 2547752 2549020 D xylitol oxidase 2547752..2549020 Streptomyces avermitilis MA-4680 1213520 NP_823267.1 CDS SAV_2091 NC_003155.4 2549143 2550417 D repressor for sugar metabolism; transcriptional regulator 2549143..2550417 Streptomyces avermitilis MA-4680 1213521 NP_823268.1 CDS SAV_2092 NC_003155.4 2550619 2551920 D sugar ABC transporter substrate-binding protein 2550619..2551920 Streptomyces avermitilis MA-4680 1213522 NP_823269.1 CDS SAV_2093 NC_003155.4 2551959 2552921 D sugar ABC transporter permeases protein 2551959..2552921 Streptomyces avermitilis MA-4680 1213523 NP_823270.1 CDS SAV_2094 NC_003155.4 2552918 2553808 D sugar ABC transporter permeases protein 2552918..2553808 Streptomyces avermitilis MA-4680 1213524 NP_823271.1 CDS bga5 NC_003155.4 2553836 2556883 D beta-galactosidase 2553836..2556883 Streptomyces avermitilis MA-4680 1210346 NP_823272.1 CDS SAV_2096 NC_003155.4 2557028 2558104 D beta-1,4-xylanase 2557028..2558104 Streptomyces avermitilis MA-4680 1213525 NP_823273.1 CDS SAV_2097 NC_003155.4 2558196 2560583 R probably MDR transport; uvrA-like protein complement(2558196..2560583) Streptomyces avermitilis MA-4680 1213526 NP_823274.1 CDS SAV_2098 NC_003155.4 2560900 2561484 D TetR family transcriptional regulator 2560900..2561484 Streptomyces avermitilis MA-4680 1213527 NP_823275.1 CDS SAV_2099 NC_003155.4 2561477 2562298 D PF00561: alpha/beta hydrolase fold; hydrolase 2561477..2562298 Streptomyces avermitilis MA-4680 1213528 NP_823276.1 CDS SAV_2100 NC_003155.4 2562322 2563719 D hypothetical protein 2562322..2563719 Streptomyces avermitilis MA-4680 1213529 NP_823277.1 CDS SAV_2101 NC_003155.4 2563757 2564527 D hypothetical protein 2563757..2564527 Streptomyces avermitilis MA-4680 1213530 NP_823278.1 CDS SAV_2102 NC_003155.4 2564514 2564933 R PF00293: NUDIX domain; hypothetical protein complement(2564514..2564933) Streptomyces avermitilis MA-4680 1213531 NP_823279.1 CDS SAV_2103 NC_003155.4 2565010 2565795 R hypothetical protein complement(2565010..2565795) Streptomyces avermitilis MA-4680 1213532 NP_823280.1 CDS SAV_2104 NC_003155.4 2565792 2566313 R hypothetical protein complement(2565792..2566313) Streptomyces avermitilis MA-4680 1213533 NP_823281.1 CDS ephB NC_003155.4 2566572 2567558 D PF00561: alpha/beta hydrolase fold; epoxide hydrolase 2566572..2567558 Streptomyces avermitilis MA-4680 1213534 NP_823282.1 CDS SAV_2106 NC_003155.4 2567544 2569253 R hypothetical protein complement(2567544..2569253) Streptomyces avermitilis MA-4680 1213535 NP_823283.1 CDS SAV_2107 NC_003155.4 2569356 2570378 R PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein complement(2569356..2570378) Streptomyces avermitilis MA-4680 1213536 NP_823284.1 CDS SAV_2108 NC_003155.4 2570591 2572267 D rhamnogalacturonase B precursor 2570591..2572267 Streptomyces avermitilis MA-4680 1213537 NP_823285.1 CDS SAV_2109 NC_003155.4 2572280 2573674 R beta-xylosidase complement(2572280..2573674) Streptomyces avermitilis MA-4680 1213538 NP_823286.1 CDS SAV_2110 NC_003155.4 2574066 2574395 D hypothetical protein 2574066..2574395 Streptomyces avermitilis MA-4680 1213539 NP_823287.1 CDS mmuM NC_003155.4 2574586 2575527 D converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 2574586..2575527 Streptomyces avermitilis MA-4680 1213540 NP_823288.1 CDS SAV_2112 NC_003155.4 2575584 2576834 R PF03747: ADP-ribosylglycohydrolase; hydrolase complement(2575584..2576834) Streptomyces avermitilis MA-4680 1213541 NP_823289.1 CDS SAV_2113 NC_003155.4 2577155 2578756 R carboxylesterase complement(2577155..2578756) Streptomyces avermitilis MA-4680 1213542 NP_823290.1 CDS SAV_2114 NC_003155.4 2579136 2580185 D LacI family transcriptional regulator 2579136..2580185 Streptomyces avermitilis MA-4680 1213543 NP_823291.1 CDS SAV_2115 NC_003155.4 2580182 2582632 D hypothetical protein 2580182..2582632 Streptomyces avermitilis MA-4680 1213544 NP_823292.1 CDS SAV_2116 NC_003155.4 2582629 2583333 R glycosyl hydrolase complement(2582629..2583333) Streptomyces avermitilis MA-4680 1213545 NP_823293.1 CDS SAV_2117 NC_003155.4 2583441 2584100 R hypothetical protein complement(2583441..2584100) Streptomyces avermitilis MA-4680 1213546 NP_823294.1 CDS SAV_2118 NC_003155.4 2584256 2584654 D quinone binding protein 2584256..2584654 Streptomyces avermitilis MA-4680 1213547 NP_823295.1 CDS SAV_2119 NC_003155.4 2584640 2585353 R AraC family transcription regulator complement(2584640..2585353) Streptomyces avermitilis MA-4680 1213548 NP_823296.1 CDS SAV_2120 NC_003155.4 2585462 2586424 R AraC family transcription regulator complement(2585462..2586424) Streptomyces avermitilis MA-4680 1213549 NP_823297.1 CDS SAV_2121 NC_003155.4 2586505 2587338 D PF01113: Dihydrodipicolinate reductase, N-terminus; hypothetical protein 2586505..2587338 Streptomyces avermitilis MA-4680 1213550 NP_823298.1 CDS SAV_2122 NC_003155.4 2587406 2588443 R PF03631: Ribonuclease BN-like family; ribonuclease BN-like family integral membrane protein complement(2587406..2588443) Streptomyces avermitilis MA-4680 1213551 NP_823299.1 CDS fadE23 NC_003155.4 2588694 2590343 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 2588694..2590343 Streptomyces avermitilis MA-4680 1210347 NP_823300.1 CDS SAV_2124 NC_003155.4 2590650 2591975 D regulatory protein 2590650..2591975 Streptomyces avermitilis MA-4680 1213552 NP_823301.1 CDS SAV_2125 NC_003155.4 2592140 2593543 D protein 2592140..2593543 Streptomyces avermitilis MA-4680 1213553 NP_823302.1 CDS cysE NC_003155.4 2593623 2594195 D acetyltransferase 2593623..2594195 Streptomyces avermitilis MA-4680 1210348 NP_823303.1 CDS nirA NC_003155.4 2594566 2596260 D ferredoxin-nitrite reductase 2594566..2596260 Streptomyces avermitilis MA-4680 1210349 NP_823304.1 CDS SAV_2128 NC_003155.4 2596328 2596507 D hypothetical protein 2596328..2596507 Streptomyces avermitilis MA-4680 1213554 NP_823305.1 CDS cysH NC_003155.4 2596504 2597241 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2596504..2597241 Streptomyces avermitilis MA-4680 1210350 NP_823306.1 CDS cysC1 NC_003155.4 2597283 2597819 D adenylylsulfate kinase 2597283..2597819 Streptomyces avermitilis MA-4680 1210351 NP_823307.1 CDS cysD1 NC_003155.4 2597816 2598751 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2597816..2598751 Streptomyces avermitilis MA-4680 1210352 NP_823308.1 CDS cysN1 NC_003155.4 2598754 2600217 D frameshift; sulfate adenylyltransferase large subunit 2598754..2600217 Streptomyces avermitilis MA-4680 1210353 NP_823309.1 CDS SAV_2133 NC_003155.4 2599904 2600110 D frameshift; sulfate adenylyltransferase subunit 1 2599904..2600110 Streptomyces avermitilis MA-4680 3238944 NP_823310.1 CDS SAV_2134 NC_003155.4 2600310 2601458 D sulfate ABC transporter substrate-binding protein 2600310..2601458 Streptomyces avermitilis MA-4680 1213555 NP_823311.1 CDS SAV_2135 NC_003155.4 2601471 2602283 D ABC transporter ATP-binding protein 2601471..2602283 Streptomyces avermitilis MA-4680 1213556 NP_823312.1 CDS SAV_2136 NC_003155.4 2602270 2603181 D ABC transporter permease 2602270..2603181 Streptomyces avermitilis MA-4680 1213557 NP_823313.1 CDS SAV_2137 NC_003155.4 2603189 2603926 D PF01903: CbiX; hypothetical protein 2603189..2603926 Streptomyces avermitilis MA-4680 1213558 NP_823314.1 CDS SAV_2138 NC_003155.4 2603984 2604580 R hypothetical protein complement(2603984..2604580) Streptomyces avermitilis MA-4680 1213559 NP_823315.1 CDS SAV_2139 NC_003155.4 2604877 2605152 D hypothetical protein 2604877..2605152 Streptomyces avermitilis MA-4680 1213560 NP_823316.1 CDS SAV_2140 NC_003155.4 2605221 2605766 R hypothetical protein complement(2605221..2605766) Streptomyces avermitilis MA-4680 1213561 NP_823317.1 CDS SAV_2141 NC_003155.4 2606063 2608336 D PF03176: MMPL family; integral membrane protein 2606063..2608336 Streptomyces avermitilis MA-4680 1213562 NP_823318.1 CDS SAV_2142 NC_003155.4 2608407 2609378 R phosphatidylglycerophosphate synthase complement(2608407..2609378) Streptomyces avermitilis MA-4680 1213563 NP_823319.1 CDS SAV_2143 NC_003155.4 2609665 2610945 R ABC transporter substrate-binding protein complement(2609665..2610945) Streptomyces avermitilis MA-4680 1213564 NP_823320.1 CDS SAV_2144 NC_003155.4 2610945 2611778 R ABC transporter permease complement(2610945..2611778) Streptomyces avermitilis MA-4680 1213565 NP_823321.1 CDS SAV_2145 NC_003155.4 2611775 2612713 R ABC transporter permease complement(2611775..2612713) Streptomyces avermitilis MA-4680 1213566 NP_823322.1 CDS SAV_2146 NC_003155.4 2612960 2613823 D PF01636: Phosphotransferase enzyme family; hypothetical protein 2612960..2613823 Streptomyces avermitilis MA-4680 1213567 NP_823323.1 CDS dnaQ3 NC_003155.4 2613862 2614584 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(2613862..2614584) Streptomyces avermitilis MA-4680 1210354 NP_823324.1 CDS SAV_2148 NC_003155.4 2614725 2616017 R hypothetical protein complement(2614725..2616017) Streptomyces avermitilis MA-4680 1213568 NP_823325.1 CDS SAV_2149 NC_003155.4 2616079 2617398 R copper amine oxidase complement(2616079..2617398) Streptomyces avermitilis MA-4680 1213569 NP_823326.1 CDS SAV_2150 NC_003155.4 2617549 2618409 R hypothetical protein complement(2617549..2618409) Streptomyces avermitilis MA-4680 1213570 NP_823327.1 CDS SAV_2151 NC_003155.4 2618580 2620688 D glycogen debranching enzyme 2618580..2620688 Streptomyces avermitilis MA-4680 1213571 NP_823328.1 CDS amyA1 NC_003155.4 2621126 2623513 D alpha-amylase 2621126..2623513 Streptomyces avermitilis MA-4680 1210355 NP_823329.1 CDS SAV_2153 NC_003155.4 2623527 2624516 R LysR family transcriptional regulator complement(2623527..2624516) Streptomyces avermitilis MA-4680 1213572 NP_823330.1 CDS lpdA2 NC_003155.4 2624596 2626032 D dihydrolipoamide dehydrogenase 2624596..2626032 Streptomyces avermitilis MA-4680 1210356 NP_823331.1 CDS SAV_2155 NC_003155.4 2626186 2627436 D PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase 2626186..2627436 Streptomyces avermitilis MA-4680 1213573 NP_823332.1 CDS sti1 NC_003155.4 2627476 2627916 R PF00720: Subtilisin inhibitor-like; subtilisin inhibitor complement(2627476..2627916) Streptomyces avermitilis MA-4680 1210357 NP_823333.1 CDS SAV_2157 NC_003155.4 2627913 2629322 R 3-hydroxyacyl-CoA dehydrogenase complement(2627913..2629322) Streptomyces avermitilis MA-4680 1213574 NP_823334.1 CDS SAV_2158 NC_003155.4 2629485 2630123 R hypothetical protein complement(2629485..2630123) Streptomyces avermitilis MA-4680 1213575 NP_823335.1 CDS amyA2 NC_003155.4 2630209 2631954 D PF00498: FHA domain; alpha-amylase 2630209..2631954 Streptomyces avermitilis MA-4680 1210358 NP_823336.1 CDS SAV_2160 NC_003155.4 2632064 2632999 R transferase complement(2632064..2632999) Streptomyces avermitilis MA-4680 1213576 NP_823337.1 CDS SAV_2161 NC_003155.4 2633043 2634188 R PF00557: metallopeptidase family M24; peptidase complement(2633043..2634188) Streptomyces avermitilis MA-4680 1213577 NP_823338.1 CDS SAV_2162 NC_003155.4 2634707 2635048 R PF00595: PDZ domain (Also known as DHR or GLGF); hypothetical protein complement(2634707..2635048) Streptomyces avermitilis MA-4680 1213578 NP_823339.1 CDS geoA NC_003155.4 2635583 2637760 R geosmin biosynthesis; germacradienol synthase complement(2635583..2637760) Streptomyces avermitilis MA-4680 1210359 NP_823340.1 CDS SAV_2164 NC_003155.4 2637962 2638741 D PF00561: alpha/beta hydrolase fold; hydrolase 2637962..2638741 Streptomyces avermitilis MA-4680 1210360 NP_823341.1 CDS SAV_2165 NC_003155.4 2638738 2640003 D CYP180A1; cytochrome P450 2638738..2640003 Streptomyces avermitilis MA-4680 1210361 NP_823342.1 CDS SAV_2166 NC_003155.4 2640012 2641226 R PF01937: Protein of unknown function DUF89; hypothetical protein complement(2640012..2641226) Streptomyces avermitilis MA-4680 1213579 NP_823343.1 CDS SAV_2167 NC_003155.4 2641219 2641800 R hypothetical protein complement(2641219..2641800) Streptomyces avermitilis MA-4680 1213580 NP_823344.1 CDS SAV_2168 NC_003155.4 2641968 2642903 D PF03067: Chitin binding domain; cellulose-binding protein 2641968..2642903 Streptomyces avermitilis MA-4680 1213581 NP_823345.1 CDS SAV_2169 NC_003155.4 2643034 2644206 R hypothetical protein complement(2643034..2644206) Streptomyces avermitilis MA-4680 1213582 NP_823346.1 CDS SAV_2170 NC_003155.4 2644470 2645144 D cholesterol esterase 2644470..2645144 Streptomyces avermitilis MA-4680 1213583 NP_823347.1 CDS SAV_2171 NC_003155.4 2645144 2645563 D hypothetical protein 2645144..2645563 Streptomyces avermitilis MA-4680 1213584 NP_823348.1 CDS SAV_2172 NC_003155.4 2645871 2646671 R SgaA homolog, PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hydroxylase complement(2645871..2646671) Streptomyces avermitilis MA-4680 1213585 NP_823349.1 CDS SAV_2173 NC_003155.4 2646843 2647331 R hypothetical protein complement(2646843..2647331) Streptomyces avermitilis MA-4680 1213586 NP_823350.1 CDS SAV_2174 NC_003155.4 2647309 2648019 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein complement(2647309..2648019) Streptomyces avermitilis MA-4680 1213587 NP_823351.1 CDS SAV_2175 NC_003155.4 2648187 2649062 D DNA-binding protein 2648187..2649062 Streptomyces avermitilis MA-4680 1213588 NP_823352.1 CDS abaA1 NC_003155.4 2649063 2649314 D regulatory protein, PF04149: Domain of unknown function (DUF397); AbaA-like protein 2649063..2649314 Streptomyces avermitilis MA-4680 1210362 NP_823353.1 CDS SAV_2177 NC_003155.4 2649403 2650233 D PF04672: Protein of unknown function (DUF574); hypothetical protein 2649403..2650233 Streptomyces avermitilis MA-4680 1213589 NP_823354.1 CDS SAV_2178 NC_003155.4 2650339 2651343 R ABC transporter substrate-binding protein complement(2650339..2651343) Streptomyces avermitilis MA-4680 1213590 NP_823355.1 CDS cvnA4 NC_003155.4 2651518 2654274 D multi-component regulatory system-4; sensor-like histidine kinase 2651518..2654274 Streptomyces avermitilis MA-4680 1210363 NP_823356.1 CDS cvnB4 NC_003155.4 2654271 2654747 D multi-component regulatory system-4, PF03259: Roadblock/LC7 domain; hypothetical protein 2654271..2654747 Streptomyces avermitilis MA-4680 1210364 NP_823357.1 CDS cvnC4 NC_003155.4 2654781 2655221 D multi-component regulatory system-4, PF05331: Protein of unknown function (DUF742); hypothetical protein 2654781..2655221 Streptomyces avermitilis MA-4680 1210365 NP_823358.1 CDS cvnD4 NC_003155.4 2655208 2655783 D multi-component regulatory system-4; ATP/GTP-binding protein 2655208..2655783 Streptomyces avermitilis MA-4680 1210366 NP_823359.1 CDS SAV_2183 NC_003155.4 2655841 2656509 R ABC transporter permease complement(2655841..2656509) Streptomyces avermitilis MA-4680 1213591 NP_823360.1 CDS SAV_2184 NC_003155.4 2656506 2657228 R ABC transporter permease complement(2656506..2657228) Streptomyces avermitilis MA-4680 1213592 NP_823361.1 CDS SAV_2185 NC_003155.4 2657225 2658352 R ABC transporter ATP-binding protein complement(2657225..2658352) Streptomyces avermitilis MA-4680 1213593 NP_823362.1 CDS agaA2 NC_003155.4 2658461 2660437 R alpha-galactosidase complement(2658461..2660437) Streptomyces avermitilis MA-4680 1210367 NP_823363.1 CDS SAV_2187 NC_003155.4 2660768 2661793 D ABC transporter substrate-binding protein 2660768..2661793 Streptomyces avermitilis MA-4680 1213594 NP_823364.1 CDS cvnA5 NC_003155.4 2662022 2664511 D multi-component regulatory system-5; sensor-like histidine kinase 2662022..2664511 Streptomyces avermitilis MA-4680 1210368 NP_823365.1 CDS cvnB5 NC_003155.4 2664523 2664954 D multi-component regulatory system-5, PF03259: Roadblock/LC7 domain; hypothetical protein 2664523..2664954 Streptomyces avermitilis MA-4680 1210369 NP_823366.1 CDS cvnC5 NC_003155.4 2664956 2665312 D multi-component regulatory system-5, PF05331: Protein of unknown function (DUF742); hypothetical protein 2664956..2665312 Streptomyces avermitilis MA-4680 1210370 NP_823367.1 CDS cvnD5 NC_003155.4 2665299 2665883 D multi-component regulatory system-5; ATP/GTP-binding protein 2665299..2665883 Streptomyces avermitilis MA-4680 1210371 NP_823368.1 CDS apbE1 NC_003155.4 2665941 2666678 R thiamine biosynthesis lipoprotein precursor complement(2665941..2666678) Streptomyces avermitilis MA-4680 1213595 NP_823369.1 CDS SAV_2193 NC_003155.4 2666680 2667099 R PF04205: FMN-binding domain; hypothetical protein complement(2666680..2667099) Streptomyces avermitilis MA-4680 1213596 NP_823370.1 CDS SAV_2194 NC_003155.4 2667119 2668537 R PF01794: Ferric reductase like transmembrane component; oxidoreductase complement(2667119..2668537) Streptomyces avermitilis MA-4680 1213597 NP_823371.1 CDS SAV_2195 NC_003155.4 2668563 2669351 D two-component system response regulator 2668563..2669351 Streptomyces avermitilis MA-4680 1213598 NP_823372.1 CDS SAV_2196 NC_003155.4 2669348 2670784 D two-component system sensor kinase 2669348..2670784 Streptomyces avermitilis MA-4680 1213599 NP_823373.1 CDS SAV_2197 NC_003155.4 2670814 2672757 R PF00733: Asparagine synthase; hypothetical protein complement(2670814..2672757) Streptomyces avermitilis MA-4680 1213600 NP_823374.1 CDS SAV_2198 NC_003155.4 2672633 2673259 R hypothetical protein complement(2672633..2673259) Streptomyces avermitilis MA-4680 1213601 NP_823375.1 CDS SAV_2199 NC_003155.4 2673659 2677531 R PF00004: ATPase family associated with various cellular activities (AAA); hypothetical protein complement(2673659..2677531) Streptomyces avermitilis MA-4680 1213602 NP_823376.1 CDS SAV_2200 NC_003155.4 2677693 2677977 D hypothetical protein 2677693..2677977 Streptomyces avermitilis MA-4680 1213603 NP_823377.1 CDS SAV_2201 NC_003155.4 2677988 2678917 D hypothetical protein 2677988..2678917 Streptomyces avermitilis MA-4680 1213604 NP_823378.1 CDS SAV_2202 NC_003155.4 2679054 2682824 D hypothetical protein 2679054..2682824 Streptomyces avermitilis MA-4680 1213605 NP_823379.1 CDS SAV_2203 NC_003155.4 2683170 2684009 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 2683170..2684009 Streptomyces avermitilis MA-4680 1213606 NP_823380.1 CDS SAV_2204 NC_003155.4 2684050 2684457 R PF01641: SelR domain; oxidoreductase complement(2684050..2684457) Streptomyces avermitilis MA-4680 1213607 NP_823381.1 CDS murC NC_003155.4 2684471 2685865 R UDP-N-acetylmuramoyl-L-alanine ligase complement(2684471..2685865) Streptomyces avermitilis MA-4680 1210372 NP_823382.1 CDS SAV_2206 NC_003155.4 2686042 2686515 R hypothetical protein complement(2686042..2686515) Streptomyces avermitilis MA-4680 1213608 NP_823383.1 CDS SAV_2208 NC_003155.4 2686713 2687531 R PF01872: RibD C-terminal domain; hypothetical protein complement(2686713..2687531) Streptomyces avermitilis MA-4680 1213609 NP_823384.1 CDS SAV_2207 NC_003155.4 2687530 2688666 D ATP/GTP-binding protein 2687530..2688666 Streptomyces avermitilis MA-4680 1213610 NP_823385.1 CDS SAV_2209 NC_003155.4 2688824 2689216 D hypothetical protein 2688824..2689216 Streptomyces avermitilis MA-4680 1213611 NP_823386.1 CDS cynT1 NC_003155.4 2689365 2689946 D carbonic anhydrase 2689365..2689946 Streptomyces avermitilis MA-4680 1210373 NP_823387.1 CDS SAV_2211 NC_003155.4 2689943 2691433 D sulfate transporter 2689943..2691433 Streptomyces avermitilis MA-4680 1213612 NP_823388.1 CDS SAV_2212 NC_003155.4 2691565 2692521 D PF01145: SPFH domain / Band 7 family; membrane protease subunit stomatin/prohibitin-like protein 2691565..2692521 Streptomyces avermitilis MA-4680 1213613 NP_823389.1 CDS SAV_2213 NC_003155.4 2692611 2693993 D PF05787: Bacterial protein of unknown function (DUF839); hypothetical protein 2692611..2693993 Streptomyces avermitilis MA-4680 1213614 NP_823390.1 CDS SAV_2214 NC_003155.4 2694231 2695100 D PF01522: Polysaccharide deacetylase; lipoprotein 2694231..2695100 Streptomyces avermitilis MA-4680 1213615 NP_823391.1 CDS SAV_2215 NC_003155.4 2695154 2695333 D hypothetical protein 2695154..2695333 Streptomyces avermitilis MA-4680 1213616 NP_823392.1 CDS SAV_2216 NC_003155.4 2695406 2696179 D PF01981: Domain of unknown function UPF0099; hypothetical protein 2695406..2696179 Streptomyces avermitilis MA-4680 1213617 NP_823393.1 CDS SAV_2217 NC_003155.4 2696357 2697145 D protein 2696357..2697145 Streptomyces avermitilis MA-4680 1213618 NP_823394.1 CDS SAV_2218 NC_003155.4 2697334 2698797 D PF05114: Protein of unknown function (DUF692); hypothetical protein 2697334..2698797 Streptomyces avermitilis MA-4680 1213619 NP_823395.1 CDS SAV_2219 NC_003155.4 2699175 2699942 D protein 2699175..2699942 Streptomyces avermitilis MA-4680 1213620 NP_823396.1 CDS SAV_2220 NC_003155.4 2700103 2700870 D integral membrane protein 2700103..2700870 Streptomyces avermitilis MA-4680 1213621 NP_823397.1 CDS SAV_2221 NC_003155.4 2701084 2701815 R PF06778: Chlorite dismutase; hypothetical protein complement(2701084..2701815) Streptomyces avermitilis MA-4680 1213622 NP_823398.1 CDS hemY NC_003155.4 2701820 2702470 R frameshift; protoporphyrinogen oxidase complement(2701820..2702470) Streptomyces avermitilis MA-4680 1210374 NP_823399.1 CDS SAV_2223 NC_003155.4 2701864 2703288 R frameshift; protoporphyrinogen oxidase complement(2701864..2703288) Streptomyces avermitilis MA-4680 1213623 NP_823400.1 CDS SAV_2224 NC_003155.4 2703486 2704460 D lipoprotein 2703486..2704460 Streptomyces avermitilis MA-4680 1213624 NP_823401.1 CDS SAV_2225 NC_003155.4 2704494 2705894 D PF00070: Pyridine nucleotide-disulphide oxidoreductase; flavoprotein oxidoreductase 2704494..2705894 Streptomyces avermitilis MA-4680 1213625 NP_823402.1 CDS SAV_2226 NC_003155.4 2705952 2706365 R hypothetical protein complement(2705952..2706365) Streptomyces avermitilis MA-4680 1213626 NP_823403.1 CDS SAV_2227 NC_003155.4 2706401 2707219 D PF01694: Rhomboid family; hypothetical protein 2706401..2707219 Streptomyces avermitilis MA-4680 1213627 NP_823404.1 CDS hemE NC_003155.4 2707230 2708297 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(2707230..2708297) Streptomyces avermitilis MA-4680 1210375 NP_823405.1 CDS SAV_2229 NC_003155.4 2708486 2709157 D hypothetical protein 2708486..2709157 Streptomyces avermitilis MA-4680 1213628 NP_823406.1 CDS SAV_2230 NC_003155.4 2709485 2710147 D two-component system response regulator 2709485..2710147 Streptomyces avermitilis MA-4680 1213629 NP_823407.1 CDS rnd NC_003155.4 2710371 2711651 D PF01612: 3'-5' exonuclease; ribonuclease D 2710371..2711651 Streptomyces avermitilis MA-4680 1210376 NP_823408.1 CDS SAV_2232 NC_003155.4 2711655 2712053 R hypothetical protein complement(2711655..2712053) Streptomyces avermitilis MA-4680 1213630 NP_823409.1 CDS fadA8 NC_003155.4 2712145 2713371 D PF00108: Thiolase, N-terminal domain; 3-ketoacyl-CoA thiolase 2712145..2713371 Streptomyces avermitilis MA-4680 1210377 NP_823410.1 CDS fadB2 NC_003155.4 2713368 2715494 D similar to glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a: including enoyl-CoA hydratase; 3-2-trans-enoyl-CoA isomerase; 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase; fatty acid oxidation complex alpha-subunit 2713368..2715494 Streptomyces avermitilis MA-4680 1210378 NP_823411.1 CDS ggaB NC_003155.4 2715592 2720106 R galactosamine-containing minor teichoic acid biosynthesis protein complement(2715592..2720106) Streptomyces avermitilis MA-4680 1210379 NP_823412.1 CDS SAV_2236 NC_003155.4 2720088 2721308 R PF01066: CDP-alcohol phosphatidyltransferase; hypothetical protein complement(2720088..2721308) Streptomyces avermitilis MA-4680 1213631 NP_823413.1 CDS SAV_2237 NC_003155.4 2721613 2723190 R hypothetical protein complement(2721613..2723190) Streptomyces avermitilis MA-4680 1213632 NP_823414.1 CDS SAV_2238 NC_003155.4 2723231 2724472 R hypothetical protein complement(2723231..2724472) Streptomyces avermitilis MA-4680 1213633 NP_823415.1 CDS galE7 NC_003155.4 2724430 2725416 R UDP-glucose 4-epimerase complement(2724430..2725416) Streptomyces avermitilis MA-4680 1210380 NP_823416.1 CDS SAV_2240 NC_003155.4 2725600 2726709 D transcriptional regulator 2725600..2726709 Streptomyces avermitilis MA-4680 1213634 NP_823417.1 CDS SAV_2241 NC_003155.4 2726824 2727189 D hypothetical protein 2726824..2727189 Streptomyces avermitilis MA-4680 1213635 NP_823418.1 CDS SAV_2242 NC_003155.4 2727250 2728743 R PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; hypothetical protein complement(2727250..2728743) Streptomyces avermitilis MA-4680 1213636 NP_823419.1 CDS SAV_2243 NC_003155.4 2728807 2730330 R PF00324: Amino acid permease; cationic amino acid transporter complement(2728807..2730330) Streptomyces avermitilis MA-4680 1213637 NP_823420.1 CDS dxs2 NC_003155.4 2730469 2732397 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(2730469..2732397) Streptomyces avermitilis MA-4680 1210381 NP_823421.1 CDS SAV_2245 NC_003155.4 2732614 2733906 R ABC transporter permease complement(2732614..2733906) Streptomyces avermitilis MA-4680 1213638 NP_823422.1 CDS SAV_2246 NC_003155.4 2733903 2734691 R ABC transporter ATP-binding protein complement(2733903..2734691) Streptomyces avermitilis MA-4680 1213639 NP_823423.1 CDS SAV_2247 NC_003155.4 2734874 2735983 R ABC transporter substrate-binding protein complement(2734874..2735983) Streptomyces avermitilis MA-4680 1213640 NP_823424.1 CDS SAV_2248 NC_003155.4 2736105 2737304 R transcriptional regulator complement(2736105..2737304) Streptomyces avermitilis MA-4680 1213641 NP_823425.1 CDS SAV_2249 NC_003155.4 2737656 2738576 R ABC transporter permease complement(2737656..2738576) Streptomyces avermitilis MA-4680 1213642 NP_823426.1 CDS SAV_2250 NC_003155.4 2738576 2739499 R PF00528: Binding-protein-dependent transport system inner membrane component; ABC transporter permease complement(2738576..2739499) Streptomyces avermitilis MA-4680 1213643 NP_823427.1 CDS SAV_2251 NC_003155.4 2739559 2741016 R ABC transporter substrate-binding protein complement(2739559..2741016) Streptomyces avermitilis MA-4680 1213644 NP_823428.1 CDS SAV_2252 NC_003155.4 2741507 2745352 D ATP/GTP-binding protein 2741507..2745352 Streptomyces avermitilis MA-4680 1213645 NP_823429.1 CDS SAV_2253 NC_003155.4 2745431 2748745 R hypothetical protein complement(2745431..2748745) Streptomyces avermitilis MA-4680 1213646 NP_823430.1 CDS celS2 NC_003155.4 2749073 2750248 R cellulose binding protein complement(2749073..2750248) Streptomyces avermitilis MA-4680 1210382 NP_823431.1 CDS SAV_2255 NC_003155.4 2750352 2750849 D hypothetical protein 2750352..2750849 Streptomyces avermitilis MA-4680 1213647 NP_823432.1 CDS SAV_2256 NC_003155.4 2750900 2752438 R two-component system sensor kinase complement(2750900..2752438) Streptomyces avermitilis MA-4680 1213648 NP_823433.1 CDS SAV_2257 NC_003155.4 2752435 2753160 R two-component system response regulator complement(2752435..2753160) Streptomyces avermitilis MA-4680 1213649 NP_823434.1 CDS acnA NC_003155.4 2753293 2756010 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(2753293..2756010) Streptomyces avermitilis MA-4680 1210383 NP_823435.1 CDS SAV_2259 NC_003155.4 2756601 2756798 D hypothetical protein 2756601..2756798 Streptomyces avermitilis MA-4680 1213650 NP_823436.1 CDS murA1 NC_003155.4 2757079 2758392 D UDP-N-acetylglucosamine transferase 2757079..2758392 Streptomyces avermitilis MA-4680 1210384 NP_823437.1 CDS SAV_2261 NC_003155.4 2758588 2759262 R hypothetical protein complement(2758588..2759262) Streptomyces avermitilis MA-4680 1213651 NP_823438.1 CDS pkn5 NC_003155.4 2759311 2761302 R serine/threonine protein kinase complement(2759311..2761302) Streptomyces avermitilis MA-4680 1210385 NP_823439.1 CDS SAV_2263 NC_003155.4 2761657 2762247 R TetR family transcriptional regulator complement(2761657..2762247) Streptomyces avermitilis MA-4680 1213652 NP_823440.1 CDS SAV_2264 NC_003155.4 2762407 2763975 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 2762407..2763975 Streptomyces avermitilis MA-4680 1213653 NP_823441.1 CDS SAV_2265 NC_003155.4 2764008 2764211 D hypothetical protein 2764008..2764211 Streptomyces avermitilis MA-4680 1213654 NP_823442.1 CDS SAV_2266 NC_003155.4 2764348 2765037 R PF00702: haloacid dehalogenase-like hydrolase; hypothetical protein complement(2764348..2765037) Streptomyces avermitilis MA-4680 1213655 NP_823443.1 CDS SAV_2267 NC_003155.4 2765027 2766250 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; oxidoreductase complement(2765027..2766250) Streptomyces avermitilis MA-4680 1213656 NP_823444.1 CDS SAV_2268 NC_003155.4 2766319 2766939 D similar to gamma-butyrolactone-dependent transcriptional regulator; TetR family transcriptional regulator 2766319..2766939 Streptomyces avermitilis MA-4680 1213657 NP_823445.1 CDS avaA NC_003155.4 2766968 2768005 R homology to BarX, FarX, AfsA, and ScbA: containing A-factor biosynthesis repeat motif; gamma-butyrolactone biosynthesis protein complement(2766968..2768005) Streptomyces avermitilis MA-4680 1210386 NP_823446.1 CDS SAV_2270 NC_003155.4 2768197 2768853 D similar to gamma-butyrolactone-dependent transcriptional regulator; TetR family transcriptional regulator 2768197..2768853 Streptomyces avermitilis MA-4680 1213658 NP_823447.2 CDS SAV_2272 NC_003155.4 2769076 2770635 R VlmK homolog, PF03972: MmgE/PrpD family; hypothetical protein complement(2769076..2770635) Streptomyces avermitilis MA-4680 1213659 NP_823449.1 CDS SAV_2273 NC_003155.4 2770752 2771120 R isomerase complement(2770752..2771120) Streptomyces avermitilis MA-4680 1213661 NP_823450.1 CDS SAV_2274 NC_003155.4 2771212 2772171 R VlmJ homolog, PF00781: Diacylglycerol kinase catalytic domain (presumed); hypothetical protein complement(2771212..2772171) Streptomyces avermitilis MA-4680 1213662 NP_823451.1 CDS SAV_2275 NC_003155.4 2772328 2773797 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(2772328..2773797) Streptomyces avermitilis MA-4680 1213663 NP_823452.1 CDS fabH7 NC_003155.4 2773878 2774897 R pks3 gene cluster; 3-oxoacyl-ACP synthase III complement(2773878..2774897) Streptomyces avermitilis MA-4680 1210387 NP_823453.1 CDS SAV_2277 NC_003155.4 2775228 2775995 R pks3 gene cluster; thioesterase complement(2775228..2775995) Streptomyces avermitilis MA-4680 1213664 NP_823454.1 CDS SAV_2278 NC_003155.4 2776016 2777119 R pks3 gene cluster, PF00296: Luciferase-like monooxygenase; F420-dependent dehydrogenase complement(2776016..2777119) Streptomyces avermitilis MA-4680 1213665 NP_823455.1 CDS SAV_2279 NC_003155.4 2777158 2778762 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2777158..2778762) Streptomyces avermitilis MA-4680 1213666 NP_823456.1 CDS pks3-1 NC_003155.4 2778808 2780709 R pks3 gene cluster; modular polyketide synthase complement(2778808..2780709) Streptomyces avermitilis MA-4680 1213667 NP_823457.1 CDS pks3-2 NC_003155.4 2780706 2784467 R pks3 gene cluster; modular polyketide synthase complement(2780706..2784467) Streptomyces avermitilis MA-4680 1213668 NP_823458.1 CDS pks3-3 NC_003155.4 2784503 2784841 R pks3 gene cluster; ACP complement(2784503..2784841) Streptomyces avermitilis MA-4680 1213669 NP_823459.1 CDS SAV_2283 NC_003155.4 2785013 2786644 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 2785013..2786644 Streptomyces avermitilis MA-4680 1213670 NP_823460.1 CDS SAV_2284 NC_003155.4 2786679 2787818 D VlmH homolog; isobutylamine N-hydroxylase 2786679..2787818 Streptomyces avermitilis MA-4680 1213671 NP_823461.1 CDS rocD3 NC_003155.4 2787876 2789159 D ornithine aminotransferase 2787876..2789159 Streptomyces avermitilis MA-4680 1213672 NP_823462.1 CDS SAV_2286 NC_003155.4 2789162 2789644 D PF03364: Streptomyces cyclase/dehydrase; hypothetical protein 2789162..2789644 Streptomyces avermitilis MA-4680 1213673 NP_823463.1 CDS SAV_2287 NC_003155.4 2789666 2790202 D hypothetical protein 2789666..2790202 Streptomyces avermitilis MA-4680 1213674 NP_823464.1 CDS SAV_2288 NC_003155.4 2790199 2790753 D PF01613: Flavin reductase like domain; NADPH-flavin oxidoreductase 2790199..2790753 Streptomyces avermitilis MA-4680 1213675 NP_823465.1 CDS SAV_2289 NC_003155.4 2790750 2791733 D VlmB homolog; hypothetical protein 2790750..2791733 Streptomyces avermitilis MA-4680 1213676 NP_823466.1 CDS fabH3 NC_003155.4 2791730 2792737 D FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase III 2791730..2792737 Streptomyces avermitilis MA-4680 1210388 NP_823467.1 CDS fabC3 NC_003155.4 2792843 2793073 D PF00550: Phosphopantetheine attachment site; ACP 2792843..2793073 Streptomyces avermitilis MA-4680 1210389 NP_823468.1 CDS fabF NC_003155.4 2793073 2794293 D PF00109: Beta-ketoacyl synthase, N-terminal domain; 3-oxoacyl-ACP synthase II 2793073..2794293 Streptomyces avermitilis MA-4680 1210390 NP_823469.1 CDS SAV_2293 NC_003155.4 2794444 2795964 D amino acid permease 2794444..2795964 Streptomyces avermitilis MA-4680 1213677 NP_823470.1 CDS serS2 NC_003155.4 2795948 2797231 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 2795948..2797231 Streptomyces avermitilis MA-4680 1210391 NP_823471.1 CDS fabI2 NC_003155.4 2797311 2798093 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(2797311..2798093) Streptomyces avermitilis MA-4680 1210392 NP_823472.1 CDS fdxC NC_003155.4 2798090 2798416 R ferredoxin complement(2798090..2798416) Streptomyces avermitilis MA-4680 1210393 NP_823473.1 CDS SAV_2297 NC_003155.4 2798419 2799828 R PF07690: Major Facilitator Superfamily; sugar transporter complement(2798419..2799828) Streptomyces avermitilis MA-4680 1213678 NP_823474.1 CDS fadS2 NC_003155.4 2800061 2801158 R PF00487: Fatty acid desaturase; fatty acid desaturase complement(2800061..2801158) Streptomyces avermitilis MA-4680 1210394 NP_823475.1 CDS SAV_2299 NC_003155.4 2801444 2801644 R hypothetical protein complement(2801444..2801644) Streptomyces avermitilis MA-4680 1213679 NP_823476.1 CDS SAV_2300 NC_003155.4 2801738 2802733 R VlmA homolog, PF04329: Family of unknown function (DUF470); hypothetical protein complement(2801738..2802733) Streptomyces avermitilis MA-4680 1213680 NP_823477.1 CDS SAV_2301 NC_003155.4 2803964 2804761 D regulatory protein 2803964..2804761 Streptomyces avermitilis MA-4680 1213681 NP_823478.1 CDS SAV_2302 NC_003155.4 2805029 2805460 D hypothetical protein 2805029..2805460 Streptomyces avermitilis MA-4680 1213682 NP_823479.1 CDS mmdA1 NC_003155.4 2805537 2807081 D PF01039: Carboxyl transferase domain; methylmalonyl-CoA decarboxylase alpha subunit 2805537..2807081 Streptomyces avermitilis MA-4680 1210395 NP_823480.1 CDS SAV_2304 NC_003155.4 2807097 2807282 D hypothetical protein 2807097..2807282 Streptomyces avermitilis MA-4680 1213683 NP_823481.1 CDS SAV_2305 NC_003155.4 2807844 2808242 R PF01042: Endoribonuclease L-PSP; hypothetical protein complement(2807844..2808242) Streptomyces avermitilis MA-4680 1213684 NP_823482.1 CDS fadE10 NC_003155.4 2808239 2809366 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(2808239..2809366) Streptomyces avermitilis MA-4680 1210396 NP_823483.1 CDS SAV_2307 NC_003155.4 2809477 2811261 D PF00501: AMP-binding enzyme; fatty acid:CoA ligase 2809477..2811261 Streptomyces avermitilis MA-4680 1213685 NP_823484.1 CDS SAV_2308 NC_003155.4 2811277 2812119 D regulator 2811277..2812119 Streptomyces avermitilis MA-4680 1213686 NP_823485.1 CDS SAV_2309 NC_003155.4 2812203 2813102 D PF00685: Sulfotransferase domain; hypothetical protein 2812203..2813102 Streptomyces avermitilis MA-4680 1213687 NP_823486.1 CDS SAV_2310 NC_003155.4 2813099 2813509 D hypothetical protein 2813099..2813509 Streptomyces avermitilis MA-4680 1213688 NP_823487.1 CDS tagE NC_003155.4 2813587 2814753 D UDP-glucose:polyglycerol phosphate glucosyltransferase 2813587..2814753 Streptomyces avermitilis MA-4680 1210397 NP_823488.1 CDS cysC2 NC_003155.4 2814750 2815301 D adenylylsulfate kinase 2814750..2815301 Streptomyces avermitilis MA-4680 1210398 NP_823489.1 CDS cysD2 NC_003155.4 2815298 2816233 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2815298..2816233 Streptomyces avermitilis MA-4680 1210399 NP_823490.1 CDS cysN2 NC_003155.4 2816236 2817456 D sulfate adenylyltransferase large subunit 2816236..2817456 Streptomyces avermitilis MA-4680 1210400 NP_823491.1 CDS SAV_2315 NC_003155.4 2817480 2819747 R catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; salicylyl-CoA 5-hydroxylase complement(2817480..2819747) Streptomyces avermitilis MA-4680 1213689 NP_823492.1 CDS echA7 NC_003155.4 2819750 2820577 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(2819750..2820577) Streptomyces avermitilis MA-4680 1210401 NP_823493.1 CDS SAV_2317 NC_003155.4 2820828 2821328 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; regulatory protein 2820828..2821328 Streptomyces avermitilis MA-4680 1213690 NP_823494.1 CDS SAV_2318 NC_003155.4 2821288 2822730 R amino acid permease complement(2821288..2822730) Streptomyces avermitilis MA-4680 1213691 NP_823495.1 CDS argF NC_003155.4 2822927 2823934 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(2822927..2823934) Streptomyces avermitilis MA-4680 1210402 NP_823496.1 CDS arcA NC_003155.4 2824044 2825273 R arginine deiminase complement(2824044..2825273) Streptomyces avermitilis MA-4680 1210403 NP_823497.1 CDS SAV_2321 NC_003155.4 2825412 2826434 D PF01145: SPFH domain / Band 7 family; hypothetical protein 2825412..2826434 Streptomyces avermitilis MA-4680 1213692 NP_823498.1 CDS SAV_2322 NC_003155.4 2826431 2827324 D PF03459: TOBE domain; hypothetical protein 2826431..2827324 Streptomyces avermitilis MA-4680 1213693 NP_823499.1 CDS prpA1 NC_003155.4 2827733 2830279 R PF00149: Calcineurin-like phosphoesterase; serine/threonine protein phosphatase complement(2827733..2830279) Streptomyces avermitilis MA-4680 1210404 NP_823500.1 CDS SAV_2324 NC_003155.4 2830276 2831763 R hypothetical protein complement(2830276..2831763) Streptomyces avermitilis MA-4680 1213694 NP_823501.1 CDS SAV_2325 NC_003155.4 2831927 2832853 D PF00296: Luciferase-like monooxygenase; monooxygenase 2831927..2832853 Streptomyces avermitilis MA-4680 1213695 NP_823502.1 CDS SAV_2326 NC_003155.4 2832931 2833392 R hypothetical protein complement(2832931..2833392) Streptomyces avermitilis MA-4680 1213696 NP_823503.1 CDS SAV_2327 NC_003155.4 2833584 2833916 R PF03819: MazG nucleotide pyrophosphohydrolase domain; hypothetical protein complement(2833584..2833916) Streptomyces avermitilis MA-4680 1213697 NP_823504.1 CDS SAV_2328 NC_003155.4 2833913 2835130 R bldA-regulated nucleotide binding protein complement(2833913..2835130) Streptomyces avermitilis MA-4680 1213698 NP_823505.1 CDS SAV_2329 NC_003155.4 2835232 2835636 R PF04472: Protein of unknown function (DUF552); hypothetical protein complement(2835232..2835636) Streptomyces avermitilis MA-4680 1213699 NP_823506.1 CDS narB NC_003155.4 2835881 2839939 D assimilatory nitrate reductase large subunit 2835881..2839939 Streptomyces avermitilis MA-4680 1210405 NP_823507.1 CDS SAV_2331 NC_003155.4 2840065 2841777 D hypothetical protein 2840065..2841777 Streptomyces avermitilis MA-4680 1213700 NP_823508.1 CDS SAV_2332 NC_003155.4 2841786 2842133 R transcription regulator ArsR complement(2841786..2842133) Streptomyces avermitilis MA-4680 1213701 NP_823509.1 CDS nicT2 NC_003155.4 2842425 2843558 D high-affinity nickel-transport protein 2842425..2843558 Streptomyces avermitilis MA-4680 1213702 NP_823510.1 CDS SAV_2334 NC_003155.4 2843585 2844349 R hypothetical protein complement(2843585..2844349) Streptomyces avermitilis MA-4680 1213703 NP_823511.1 CDS SAV_2335 NC_003155.4 2844389 2845000 R hypothetical protein complement(2844389..2845000) Streptomyces avermitilis MA-4680 1213704 NP_823512.1 CDS SAV_2336 NC_003155.4 2845071 2850074 R regulatory protein complement(2845071..2850074) Streptomyces avermitilis MA-4680 1213705 NP_823513.1 CDS SAV_2337 NC_003155.4 2850071 2851015 R PF07728: ATPase family associated with various cellular activities (AAA); MoxR-like ATPase complement(2850071..2851015) Streptomyces avermitilis MA-4680 1213706 NP_823514.1 CDS SAV_2338 NC_003155.4 2851012 2853117 R hypothetical protein complement(2851012..2853117) Streptomyces avermitilis MA-4680 1213707 NP_823515.1 CDS SAV_2339 NC_003155.4 2853138 2854208 R hypothetical protein complement(2853138..2854208) Streptomyces avermitilis MA-4680 1213708 NP_823516.1 CDS SAV_2340 NC_003155.4 2854441 2854833 D substrate-binding protein 2854441..2854833 Streptomyces avermitilis MA-4680 1213709 NP_823517.1 CDS SAV_2341 NC_003155.4 2855062 2855481 D molibdenum binding protein 2855062..2855481 Streptomyces avermitilis MA-4680 1213710 NP_823518.1 CDS SAV_2342 NC_003155.4 2855649 2856317 D PF00597: DedA family; hypothetical protein 2855649..2856317 Streptomyces avermitilis MA-4680 1213711 NP_823519.1 CDS SAV_2343 NC_003155.4 2856344 2857687 R PF03706: Uncharacterised protein family (UPF0104); hypothetical protein complement(2856344..2857687) Streptomyces avermitilis MA-4680 1213712 NP_823520.1 CDS SAV_2344 NC_003155.4 2857684 2859243 R hypothetical protein complement(2857684..2859243) Streptomyces avermitilis MA-4680 1213713 NP_823521.1 CDS SAV_2345 NC_003155.4 2859641 2860309 R PF00106: short chain dehydrogenase; dehydrogenase complement(2859641..2860309) Streptomyces avermitilis MA-4680 1213714 NP_823522.1 CDS SAV_2346 NC_003155.4 2860718 2861371 D cell wall surface anchor family protein; hypothetical protein 2860718..2861371 Streptomyces avermitilis MA-4680 1213715 NP_823523.1 CDS gvpK3 NC_003155.4 2861430 2861708 R gas vesicle synthesis protein complement(2861430..2861708) Streptomyces avermitilis MA-4680 1210406 NP_823524.1 CDS gvpS3 NC_003155.4 2861705 2861932 R gas vesicle synthesis protein complement(2861705..2861932) Streptomyces avermitilis MA-4680 1210407 NP_823525.1 CDS gvpL3 NC_003155.4 2861936 2862751 R gas vesicle synthesis protein complement(2861936..2862751) Streptomyces avermitilis MA-4680 1210408 NP_823526.1 CDS gvpJ3 NC_003155.4 2862748 2863107 R gas vesicle synthesis protein complement(2862748..2863107) Streptomyces avermitilis MA-4680 1210409 NP_823527.1 CDS SAV_2351 NC_003155.4 2863100 2864230 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(2863100..2864230) Streptomyces avermitilis MA-4680 1213716 NP_823528.1 CDS SAV_2352 NC_003155.4 2864237 2865367 R hypothetical protein complement(2864237..2865367) Streptomyces avermitilis MA-4680 1213717 NP_823529.1 CDS gvpG3 NC_003155.4 2865374 2865628 R gas vesicle synthesis protein complement(2865374..2865628) Streptomyces avermitilis MA-4680 1210410 NP_823530.1 CDS gvpF3 NC_003155.4 2865630 2866379 R gas vesicle synthesis protein complement(2865630..2866379) Streptomyces avermitilis MA-4680 1210411 NP_823531.1 CDS gvpA3 NC_003155.4 2866383 2866853 R similar to the gas vesicle synthesis protein GvpA in other bacteria but contains an extended C-terminal tail; function in the Streptomyces group is unknown but they contain several homologs of other gas vesicle synthesis proteins; gas vesicle synthesis-like protein complement(2866383..2866853) Streptomyces avermitilis MA-4680 1210412 NP_823532.1 CDS gvpO3 NC_003155.4 2866887 2867207 R gas vesicle synthesis protein complement(2866887..2867207) Streptomyces avermitilis MA-4680 1210413 NP_823533.1 CDS SAV_2357 NC_003155.4 2867520 2867744 R hypothetical protein complement(2867520..2867744) Streptomyces avermitilis MA-4680 1213718 NP_823534.1 CDS SAV_2358 NC_003155.4 2867801 2868622 R PF00106: short chain dehydrogenase; dehydrogenase complement(2867801..2868622) Streptomyces avermitilis MA-4680 1213719 NP_823535.1 CDS SAV_2359 NC_003155.4 2868840 2869376 D hypothetical protein 2868840..2869376 Streptomyces avermitilis MA-4680 1213720 NP_823536.1 CDS SAV_2360 NC_003155.4 2869373 2870353 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 2869373..2870353 Streptomyces avermitilis MA-4680 1213721 NP_823537.1 CDS SAV_2361 NC_003155.4 2870350 2871699 D sugar ABC transporter substrate-binding protein 2870350..2871699 Streptomyces avermitilis MA-4680 1213722 NP_823538.1 CDS SAV_2362 NC_003155.4 2871696 2872658 D sugar ABC transporter permease 2871696..2872658 Streptomyces avermitilis MA-4680 1213723 NP_823539.1 CDS SAV_2363 NC_003155.4 2872697 2873524 D ABC transporter permease 2872697..2873524 Streptomyces avermitilis MA-4680 1213724 NP_823540.1 CDS SAV_2364 NC_003155.4 2873756 2875672 R ABC transporter ATP-binding protein complement(2873756..2875672) Streptomyces avermitilis MA-4680 1213725 NP_823541.1 CDS SAV_2365 NC_003155.4 2875669 2877462 R ABC transporter ATP-binding protein complement(2875669..2877462) Streptomyces avermitilis MA-4680 1213726 NP_823542.1 CDS SAV_2366 NC_003155.4 2877941 2878606 D pks5 gene cluster; hydroxylase 2877941..2878606 Streptomyces avermitilis MA-4680 1213727 NP_823543.1 CDS SAV_2367 NC_003155.4 2878682 2880001 R enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase complement(2878682..2880001) Streptomyces avermitilis MA-4680 1213728 NP_823544.1 CDS pks5 NC_003155.4 2879868 2893364 R pks5 gene cluster; modular polyketide synthase complement(2879868..2893364) Streptomyces avermitilis MA-4680 1213729 NP_823545.1 CDS SAV_2369 NC_003155.4 2893601 2894413 D pks5 gene cluster; regulatory protein 2893601..2894413 Streptomyces avermitilis MA-4680 1213730 NP_823546.1 CDS fabG NC_003155.4 2894488 2895315 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(2894488..2895315) Streptomyces avermitilis MA-4680 1213731 NP_823547.1 CDS SAV_2371 NC_003155.4 2895312 2895968 R two-component system response regulator complement(2895312..2895968) Streptomyces avermitilis MA-4680 1213732 NP_823548.1 CDS SAV_2372 NC_003155.4 2896543 2897352 R methyltransferase complement(2896543..2897352) Streptomyces avermitilis MA-4680 1213733 NP_823549.1 CDS pks9-1 NC_003155.4 2897395 2897655 R pks9 gene cluster, similar to actIORF3; ACP complement(2897395..2897655) Streptomyces avermitilis MA-4680 1213734 NP_823550.1 CDS pks9-2 NC_003155.4 2897904 2898908 D pks9 gene cluster; 3-oxoacyl-ACP synthase III 2897904..2898908 Streptomyces avermitilis MA-4680 1213735 NP_823551.1 CDS pks9-3 NC_003155.4 2899008 2900258 R pks9 gene cluster, similar to actIORF2; 3-oxoacyl-ACP synthase II complement(2899008..2900258) Streptomyces avermitilis MA-4680 1213736 NP_823552.1 CDS pks9-4 NC_003155.4 2900251 2901483 R pks9 gene cluster, similar to actIORF1; 3-oxoacyl-ACP synthase I complement(2900251..2901483) Streptomyces avermitilis MA-4680 1213737 NP_823553.1 CDS cyp10 NC_003155.4 2901616 2902815 R CYP107Y1, pks9 gene cluster; cytochrome P450 complement(2901616..2902815) Streptomyces avermitilis MA-4680 1210414 NP_823554.1 CDS SAV_2378 NC_003155.4 2903139 2904644 R pks9 gene cluster, PF01360: Monooxygenase; polyketide oxidase/hydroxylase complement(2903139..2904644) Streptomyces avermitilis MA-4680 1213738 NP_823555.1 CDS SAV_2379 NC_003155.4 2904712 2905497 R pks9 gene cluster; hypothetical protein complement(2904712..2905497) Streptomyces avermitilis MA-4680 1213739 NP_823556.1 CDS SAV_2380 NC_003155.4 2905494 2906435 R pks9 gene cluster; ABC transporter ATP-binding protein complement(2905494..2906435) Streptomyces avermitilis MA-4680 1213740 NP_823557.1 CDS SAV_2381 NC_003155.4 2906589 2907374 D pks9 gene cluster; TetR family transcriptional regulator 2906589..2907374 Streptomyces avermitilis MA-4680 1213741 NP_823558.1 CDS SAV_2382 NC_003155.4 2907341 2908420 R pks9 gene cluster; O-methyltransferase complement(2907341..2908420) Streptomyces avermitilis MA-4680 1213742 NP_823559.1 CDS SAV_2383 NC_003155.4 2908487 2909455 R pks9 gene cluster, similar to actVII; aromatase complement(2908487..2909455) Streptomyces avermitilis MA-4680 1213743 NP_823560.1 CDS SAV_2384 NC_003155.4 2909637 2910314 D pks9 gene cluster; cyclase 2909637..2910314 Streptomyces avermitilis MA-4680 1213744 NP_823561.1 CDS cyp11 NC_003155.4 2910356 2911516 D CYP181A1, pks9 gene cluster; cytochrome P450 2910356..2911516 Streptomyces avermitilis MA-4680 1210415 NP_823562.1 CDS SAV_2386 NC_003155.4 2911652 2912356 D pks9 gene cluster; ClpX-like protein 2911652..2912356 Streptomyces avermitilis MA-4680 1213745 NP_823563.1 CDS SAV_2387 NC_003155.4 2912795 2913535 D pks9 gene cluster; 3-oxoacyl-ACP reductase 2912795..2913535 Streptomyces avermitilis MA-4680 1213746 NP_823564.1 CDS SAV_2388 NC_003155.4 2914052 2914291 D probably pseudogene; phosphopantetheinyl transferase 2914052..2914291 Streptomyces avermitilis MA-4680 1213747 NP_823565.1 CDS SAV_2389 NC_003155.4 2914573 2915874 R RNA methyltransferase complement(2914573..2915874) Streptomyces avermitilis MA-4680 1213748 NP_823566.1 CDS SAV_2390 NC_003155.4 2915994 2918045 R amino acid permease complement(2915994..2918045) Streptomyces avermitilis MA-4680 1213749 NP_823567.1 CDS trkA NC_003155.4 2918457 2919128 D PF02254: TrkA-N domain; potassium transporter 2918457..2919128 Streptomyces avermitilis MA-4680 1210416 NP_823568.1 CDS trkB NC_003155.4 2919128 2919805 D PF02254: TrkA-N domain; potassium transporter 2919128..2919805 Streptomyces avermitilis MA-4680 1210417 NP_823569.1 CDS SAV_2393 NC_003155.4 2919948 2920715 R hypothetical protein complement(2919948..2920715) Streptomyces avermitilis MA-4680 1213750 NP_823570.1 CDS SAV_2394 NC_003155.4 2920719 2921237 R hypothetical protein complement(2920719..2921237) Streptomyces avermitilis MA-4680 1213751 NP_823571.1 CDS kdpE NC_003155.4 2921239 2921955 R PF00072: Response regulator receiver domain; two-component system response regulator for high-affinity potassium transport system complement(2921239..2921955) Streptomyces avermitilis MA-4680 1210418 NP_823572.1 CDS kdpD NC_003155.4 2921949 2924504 R PF02702: Osmosensitive K+ channel His kinase sensor domain; two-component system sensor kinase for high-affinity potassium transport system complement(2921949..2924504) Streptomyces avermitilis MA-4680 1210419 NP_823573.1 CDS SAV_2397 NC_003155.4 2924628 2925842 R protein complement(2924628..2925842) Streptomyces avermitilis MA-4680 1213752 NP_823574.1 CDS SAV_2398 NC_003155.4 2926016 2926780 R hypothetical protein complement(2926016..2926780) Streptomyces avermitilis MA-4680 1213753 NP_823575.1 CDS dut NC_003155.4 2926782 2927309 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(2926782..2927309) Streptomyces avermitilis MA-4680 1210420 NP_823576.1 CDS SAV_2400 NC_003155.4 2927306 2927890 R PF03061: Thioesterase superfamily; hypothetical protein complement(2927306..2927890) Streptomyces avermitilis MA-4680 1213754 NP_823577.1 CDS SAV_2401 NC_003155.4 2927949 2928410 D protein 2927949..2928410 Streptomyces avermitilis MA-4680 1213755 NP_823578.1 CDS SAV_2402 NC_003155.4 2928537 2929472 R hypothetical protein complement(2928537..2929472) Streptomyces avermitilis MA-4680 1213756 NP_823579.1 CDS SAV_2403 NC_003155.4 2929486 2929782 R hypothetical protein complement(2929486..2929782) Streptomyces avermitilis MA-4680 1213757 NP_823580.1 CDS cutS NC_003155.4 2930179 2931426 R transfer copper to melC; two-component system sensor kinase complement(2930179..2931426) Streptomyces avermitilis MA-4680 1210421 NP_823581.1 CDS cutR NC_003155.4 2931433 2932086 R two-component system response regulator complement(2931433..2932086) Streptomyces avermitilis MA-4680 1210422 NP_823582.1 CDS suhB1 NC_003155.4 2932782 2933600 R spectinomycin resistance or Li+ sensitivity. extragenic suppressor protein homolog, PF00459: Inositol monophosphatase family; myo-inositol 1-monophosphatase complement(2932782..2933600) Streptomyces avermitilis MA-4680 1210423 NP_823583.1 CDS hemH NC_003155.4 2933609 2934736 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(2933609..2934736) Streptomyces avermitilis MA-4680 1210424 NP_823584.1 CDS SAV_2408 NC_003155.4 2934898 2936136 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 2934898..2936136 Streptomyces avermitilis MA-4680 1213758 NP_823585.1 CDS SAV_2409 NC_003155.4 2936096 2937415 D PF01565: FAD binding domain; FAD-dependent oxidoreductase 2936096..2937415 Streptomyces avermitilis MA-4680 1213759 NP_823586.1 CDS SAV_2410 NC_003155.4 2937339 2938130 R hypothetical protein complement(2937339..2938130) Streptomyces avermitilis MA-4680 1213760 NP_823587.1 CDS SAV_2411 NC_003155.4 2938603 2939649 D DNA-binding protein 2938603..2939649 Streptomyces avermitilis MA-4680 1213761 NP_823588.1 CDS sseB NC_003155.4 2939732 2940583 R thiosulfate sulfurtransferase complement(2939732..2940583) Streptomyces avermitilis MA-4680 1210425 NP_823589.1 CDS SAV_2413 NC_003155.4 2940907 2941710 D SgaA homolog; hydroxylase 2940907..2941710 Streptomyces avermitilis MA-4680 1213762 NP_823590.1 CDS tdk NC_003155.4 2941783 2942433 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(2941783..2942433) Streptomyces avermitilis MA-4680 1210426 NP_823591.1 CDS SAV_2415 NC_003155.4 2942495 2943682 R PF01663: Type I phosphodiesterase / nucleotide pyrophosphatase; phosphodiesterase complement(2942495..2943682) Streptomyces avermitilis MA-4680 1213763 NP_823592.1 CDS SAV_2416 NC_003155.4 2943682 2944269 R hypothetical protein complement(2943682..2944269) Streptomyces avermitilis MA-4680 1213764 NP_823593.1 CDS acdA2 NC_003155.4 2944322 2947171 R acyl-CoA synthetase (NDP forming type) complement(2944322..2947171) Streptomyces avermitilis MA-4680 1213765 NP_823594.1 CDS hpr NC_003155.4 2947307 2947588 D PF00381: PTS HPr component phosphorylation site; phosphocarrier protein 2947307..2947588 Streptomyces avermitilis MA-4680 1210427 NP_823595.1 CDS SAV_2419 NC_003155.4 2947869 2948564 R GntR family transcriptional regulator complement(2947869..2948564) Streptomyces avermitilis MA-4680 1213766 NP_823596.1 CDS SAV_2420 NC_003155.4 2948761 2949537 R PF01551: Peptidase family M23; peptidase complement(2948761..2949537) Streptomyces avermitilis MA-4680 1213767 NP_823597.1 CDS SAV_2421 NC_003155.4 2949913 2951301 R PF05193: Peptidase M16 inactive domain; protease complement(2949913..2951301) Streptomyces avermitilis MA-4680 1213768 NP_823598.1 CDS SAV_2422 NC_003155.4 2951298 2952662 R PF05193: Peptidase M16 inactive domain; protease complement(2951298..2952662) Streptomyces avermitilis MA-4680 1213769 NP_823599.1 CDS parC NC_003155.4 2952967 2955423 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 2952967..2955423 Streptomyces avermitilis MA-4680 1210428 NP_823600.1 CDS cobW NC_003155.4 2955436 2956521 R cobalamin biosynthesis, PF02492: CobW/HypB/UreG, nucleotide-binding domain; cobalamin synthesis protein complement(2955436..2956521) Streptomyces avermitilis MA-4680 1210429 NP_823601.1 CDS SAV_2425 NC_003155.4 2956894 2957415 D protein 2956894..2957415 Streptomyces avermitilis MA-4680 1213770 NP_823602.1 CDS SAV_2426 NC_003155.4 2957588 2957917 D hypothetical protein 2957588..2957917 Streptomyces avermitilis MA-4680 1213771 NP_823603.1 CDS citA3 NC_003155.4 2957989 2959155 R citrate synthase complement(2957989..2959155) Streptomyces avermitilis MA-4680 1210430 NP_823604.1 CDS SAV_2428 NC_003155.4 2959252 2960508 D PF00285: Citrate synthase; citrate synthase-like protein 2959252..2960508 Streptomyces avermitilis MA-4680 1213772 NP_823605.1 CDS SAV_2429 NC_003155.4 2960607 2961554 D PF06091: Bacterial protein of unknown function (DUF942); hypothetical protein 2960607..2961554 Streptomyces avermitilis MA-4680 1213773 NP_823606.1 CDS SAV_2430 NC_003155.4 2961753 2963480 D two-component system sensor kinase 2961753..2963480 Streptomyces avermitilis MA-4680 1213774 NP_823607.1 CDS SAV_2431 NC_003155.4 2963477 2964166 D two-component system response regulator 2963477..2964166 Streptomyces avermitilis MA-4680 1213775 NP_823608.1 CDS SAV_2432 NC_003155.4 2964195 2965256 R ABC transporter substrate-binding protein complement(2964195..2965256) Streptomyces avermitilis MA-4680 1213776 NP_823609.1 CDS SAV_2433 NC_003155.4 2965387 2966280 R ABC transporter permease complement(2965387..2966280) Streptomyces avermitilis MA-4680 1213777 NP_823610.1 CDS SAV_2434 NC_003155.4 2966252 2967103 R ABC transporter ATP-binding protein complement(2966252..2967103) Streptomyces avermitilis MA-4680 1213778 NP_823611.1 CDS SAV_2435 NC_003155.4 2967230 2967922 D two-component system response regulator 2967230..2967922 Streptomyces avermitilis MA-4680 1213779 NP_823612.1 CDS SAV_2436 NC_003155.4 2967960 2969552 R PF00474: Sodium:solute symporter family; sodium:solute symporter complement(2967960..2969552) Streptomyces avermitilis MA-4680 1213780 NP_823613.1 CDS SAV_2437 NC_003155.4 2969549 2970079 R PF04341: Protein of unknown function, DUF485; hypothetical protein complement(2969549..2970079) Streptomyces avermitilis MA-4680 1213781 NP_823614.1 CDS SAV_2438 NC_003155.4 2970142 2970825 R two-component system response regulator complement(2970142..2970825) Streptomyces avermitilis MA-4680 1213782 NP_823615.1 CDS SAV_2439 NC_003155.4 2970822 2971976 R two-component system sensor kinase complement(2970822..2971976) Streptomyces avermitilis MA-4680 1213783 NP_823616.1 CDS SAV_2440 NC_003155.4 2971973 2972521 R integral membrane protein complement(2971973..2972521) Streptomyces avermitilis MA-4680 1213784 NP_823617.1 CDS SAV_2441 NC_003155.4 2972580 2972771 R hypothetical protein complement(2972580..2972771) Streptomyces avermitilis MA-4680 1213785 NP_823618.1 CDS parE NC_003155.4 2972825 2974948 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(2972825..2974948) Streptomyces avermitilis MA-4680 1210431 NP_823619.1 CDS SAV_2443 NC_003155.4 2975869 2976687 R PF00089: Trypsin; serine protease complement(2975869..2976687) Streptomyces avermitilis MA-4680 1213786 NP_823620.1 CDS rpoD NC_003155.4 2976855 2978393 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor complement(2976855..2978393) Streptomyces avermitilis MA-4680 1210432 NP_823621.1 CDS whiH NC_003155.4 2979000 2979863 R GntR-family transcriptional regulator; sporulation transcription factor complement(2979000..2979863) Streptomyces avermitilis MA-4680 1213787 NP_823622.1 CDS SAV_2446 NC_003155.4 2980050 2981795 R ABC transporter ATP-binding protein complement(2980050..2981795) Streptomyces avermitilis MA-4680 1213788 NP_823623.1 CDS SAV_2447 NC_003155.4 2981909 2982661 R PF00293: NUDIX domain; DNA hydrolase complement(2981909..2982661) Streptomyces avermitilis MA-4680 1213789 NP_823624.1 CDS SAV_2448 NC_003155.4 2982785 2985184 R glycogen debranching enzyme complement(2982785..2985184) Streptomyces avermitilis MA-4680 1213790 NP_823625.1 CDS SAV_2449 NC_003155.4 2985293 2987020 R hypothetical protein complement(2985293..2987020) Streptomyces avermitilis MA-4680 1213791 NP_823626.1 CDS SAV_2450 NC_003155.4 2987332 2989536 D PF00270: DEAD/DEAH box helicase; ATP-dependent DNA helicase 2987332..2989536 Streptomyces avermitilis MA-4680 1213792 NP_823627.1 CDS SAV_2451 NC_003155.4 2989772 2990407 D hypothetical protein 2989772..2990407 Streptomyces avermitilis MA-4680 1213793 NP_823628.1 CDS SAV_2452 NC_003155.4 2990953 2991579 R hypothetical protein complement(2990953..2991579) Streptomyces avermitilis MA-4680 1213794 NP_823629.1 CDS rnhB NC_003155.4 2991649 2992350 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(2991649..2992350) Streptomyces avermitilis MA-4680 1210433 NP_823630.1 CDS SAV_2454 NC_003155.4 2992627 2993250 R TetR family transcriptional regulator complement(2992627..2993250) Streptomyces avermitilis MA-4680 1213795 NP_823631.1 CDS SAV_2455 NC_003155.4 2993440 2994999 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 2993440..2994999 Streptomyces avermitilis MA-4680 1213796 NP_823632.1 CDS SAV_2456 NC_003155.4 2995226 2997046 R hypothetical protein complement(2995226..2997046) Streptomyces avermitilis MA-4680 1213797 NP_823633.1 CDS SAV_2457 NC_003155.4 2997383 2998288 R PF03747: ADP-ribosylglycohydrolase; hydrolase complement(2997383..2998288) Streptomyces avermitilis MA-4680 1213798 NP_823634.1 CDS SAV_2458 NC_003155.4 2998301 2998960 R PF00300: Phosphoglycerate mutase family; hypothetical protein complement(2998301..2998960) Streptomyces avermitilis MA-4680 1213799 NP_823635.1 CDS SAV_2459 NC_003155.4 2999154 2999759 R hypothetical protein complement(2999154..2999759) Streptomyces avermitilis MA-4680 1213800 NP_823636.1 CDS SAV_2460 NC_003155.4 2999916 3000449 D hypothetical protein 2999916..3000449 Streptomyces avermitilis MA-4680 1213801 NP_823637.1 CDS nrdA NC_003155.4 3000542 3003436 R catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis; vitamin B12-dependent ribonucleotide reductase complement(3000542..3003436) Streptomyces avermitilis MA-4680 1210434 NP_823638.1 CDS nrdR NC_003155.4 3003586 3004149 R transcriptional regulator NrdR complement(3003586..3004149) Streptomyces avermitilis MA-4680 1213802 NP_823639.1 CDS lexA NC_003155.4 3004668 3005447 D Represses a number of genes involved in the response to DNA damage; LexA repressor 3004668..3005447 Streptomyces avermitilis MA-4680 1210435 NP_823640.1 CDS dinG NC_003155.4 3005610 3007643 R ATP-dependent helicase complement(3005610..3007643) Streptomyces avermitilis MA-4680 1210436 NP_823641.1 CDS SAV_2465 NC_003155.4 3007876 3009009 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(3007876..3009009) Streptomyces avermitilis MA-4680 1213803 NP_823642.1 CDS SAV_2466 NC_003155.4 3009049 3011109 R iron transport protein complement(3009049..3011109) Streptomyces avermitilis MA-4680 1213804 NP_823643.1 CDS SAV_2467 NC_003155.4 3011275 3012729 R class III aminotransferase complement(3011275..3012729) Streptomyces avermitilis MA-4680 1213805 NP_823644.1 CDS SAV_2468 NC_003155.4 3013261 3014493 D protein 3013261..3014493 Streptomyces avermitilis MA-4680 1213806 NP_823645.1 CDS SAV_2469 NC_003155.4 3014689 3015882 D protein 3014689..3015882 Streptomyces avermitilis MA-4680 1213807 NP_823646.1 CDS SAV_2470 NC_003155.4 3015948 3017441 R ATP/GTP-binding protein complement(3015948..3017441) Streptomyces avermitilis MA-4680 1213808 NP_823647.1 CDS SAV_2471 NC_003155.4 3017627 3019096 R PF01433: Peptidase family M1; metallopeptidase complement(3017627..3019096) Streptomyces avermitilis MA-4680 1213809 NP_823648.1 CDS relA1 NC_003155.4 3019308 3021470 R PF04607: Region found in RelA / SpoT proteins; ppGpp synthetase/hydrolase complement(3019308..3021470) Streptomyces avermitilis MA-4680 1210437 NP_823649.1 CDS dapF NC_003155.4 3021769 3022638 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(3021769..3022638) Streptomyces avermitilis MA-4680 1210438 NP_823650.1 CDS SAV_2474 NC_003155.4 3022962 3023495 R hypothetical protein complement(3022962..3023495) Streptomyces avermitilis MA-4680 1213810 NP_823651.1 CDS miaA NC_003155.4 3023598 3024536 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(3023598..3024536) Streptomyces avermitilis MA-4680 1210439 NP_823652.1 CDS SAV_2476 NC_003155.4 3024719 3025084 D hypothetical protein 3024719..3025084 Streptomyces avermitilis MA-4680 1213811 NP_823653.1 CDS SAV_2477 NC_003155.4 3025109 3025384 D hypothetical protein 3025109..3025384 Streptomyces avermitilis MA-4680 1213812 NP_823654.1 CDS SAV_2478 NC_003155.4 3025529 3026248 R PF02900: Catalytic LigB subunit of aromatic ring-opening dioxygenase; hypothetical protein complement(3025529..3026248) Streptomyces avermitilis MA-4680 1213813 NP_823655.1 CDS SAV_2479 NC_003155.4 3026318 3027844 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(3026318..3027844) Streptomyces avermitilis MA-4680 1213814 NP_823656.1 CDS SAV_2480 NC_003155.4 3027958 3028434 R PF03819: MazG nucleotide pyrophosphohydrolase domain; hypothetical protein complement(3027958..3028434) Streptomyces avermitilis MA-4680 1213815 NP_823657.1 CDS SAV_2481 NC_003155.4 3028547 3029545 D PF03466: LysR substrate binding domain; protein 3028547..3029545 Streptomyces avermitilis MA-4680 1213816 NP_823658.1 CDS SAV_2482 NC_003155.4 3029568 3030974 R two-component system sensor kinase complement(3029568..3030974) Streptomyces avermitilis MA-4680 1213817 NP_823659.1 CDS SAV_2483 NC_003155.4 3030984 3031670 R two-component system response regulator complement(3030984..3031670) Streptomyces avermitilis MA-4680 1213818 NP_823660.1 CDS gluA2 NC_003155.4 3031983 3032759 D ABC transporter ATP-binding protein; glutamate uptake system ATP-binding protein 3031983..3032759 Streptomyces avermitilis MA-4680 1210440 NP_823661.1 CDS gluB2 NC_003155.4 3032876 3033709 D ABC transporter substrate-binding protein; glutamate ABC transporter substrate-binding protein 3032876..3033709 Streptomyces avermitilis MA-4680 1210441 NP_823662.1 CDS gluC2 NC_003155.4 3033795 3034460 D ABC transporter permease; glutamate ABC transporter permease 3033795..3034460 Streptomyces avermitilis MA-4680 1210442 NP_823663.1 CDS gluD2 NC_003155.4 3034457 3035362 D ABC transporter permease; glutamate ABC transporter permease 3034457..3035362 Streptomyces avermitilis MA-4680 1210443 NP_823664.1 CDS SAV_2488 NC_003155.4 3035563 3037428 D PF01360: Monooxygenase; monooxygenase 3035563..3037428 Streptomyces avermitilis MA-4680 1213819 NP_823665.1 CDS cdo1 NC_003155.4 3037719 3038264 D PF05995: cysteine dioxygenase type I; cysteine dioxygenase 3037719..3038264 Streptomyces avermitilis MA-4680 1213820 NP_823666.1 CDS SAV_2490 NC_003155.4 3038261 3038662 D PF00581: Rhodanese-like domain; hypothetical protein 3038261..3038662 Streptomyces avermitilis MA-4680 1213821 NP_823667.2 CDS recX NC_003155.4 3038800 3039597 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3038800..3039597) Streptomyces avermitilis MA-4680 1210444 NP_823668.1 CDS recA NC_003155.4 3039751 3040884 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3039751..3040884) Streptomyces avermitilis MA-4680 1210445 NP_823669.1 CDS SAV_2493 NC_003155.4 3041349 3042380 D hypothetical protein 3041349..3042380 Streptomyces avermitilis MA-4680 1213822 NP_823670.1 CDS SAV_2494 NC_003155.4 3042423 3043574 R PF01594: Domain of unknown function DUF20; hypothetical protein complement(3042423..3043574) Streptomyces avermitilis MA-4680 1213823 NP_823671.1 CDS SAV_2495 NC_003155.4 3043786 3043980 R hypothetical protein complement(3043786..3043980) Streptomyces avermitilis MA-4680 1213824 NP_823672.1 CDS SAV_2496 NC_003155.4 3044061 3045005 D hypothetical protein 3044061..3045005 Streptomyces avermitilis MA-4680 1213825 NP_823673.1 CDS SAV_2497 NC_003155.4 3045039 3045347 R PF06063: Domain of unknown function (DUF931); hypothetical protein complement(3045039..3045347) Streptomyces avermitilis MA-4680 1213826 NP_823674.1 CDS SAV_2498 NC_003155.4 3045344 3046252 R PF03591: AzlC protein; hypothetical protein complement(3045344..3046252) Streptomyces avermitilis MA-4680 1213827 NP_823675.1 CDS SAV_2499 NC_003155.4 3046200 3047096 R AraC family transcription regulator complement(3046200..3047096) Streptomyces avermitilis MA-4680 1213828 NP_823676.1 CDS lhr NC_003155.4 3047311 3052287 D PF00270: DEAD/DEAH box helicase; ATP-dependent DNA helicase 3047311..3052287 Streptomyces avermitilis MA-4680 1210446 NP_823677.1 CDS nei1 NC_003155.4 3052491 3053333 D involved in DNA repair; nick DNA at apurinic/apyrimidinic sites. PF01149: Formamidopyrimidine-DNA glycosylase N-terminal domain; endonuclease VIII and DNA N-glycosylase with an AP lyase activity 3052491..3053333 Streptomyces avermitilis MA-4680 1210447 NP_823678.1 CDS fabG3 NC_003155.4 3053367 3054131 D PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase 3053367..3054131 Streptomyces avermitilis MA-4680 1210448 NP_823679.1 CDS SAV_2503 NC_003155.4 3054324 3054602 R hypothetical protein complement(3054324..3054602) Streptomyces avermitilis MA-4680 1213829 NP_823680.1 CDS mrgA2 NC_003155.4 3054804 3055274 R PF00210: ferritin-like domain; starvation-induced DNA protecting protein complement(3054804..3055274) Streptomyces avermitilis MA-4680 1213830 NP_823681.1 CDS SAV_2505 NC_003155.4 3055519 3055896 R DNA-binding protein complement(3055519..3055896) Streptomyces avermitilis MA-4680 1213831 NP_823682.1 CDS SAV_2506 NC_003155.4 3056006 3056551 R competence-damage inducible protein complement(3056006..3056551) Streptomyces avermitilis MA-4680 1213832 NP_823683.1 CDS pgsA1 NC_003155.4 3056548 3057396 R phosphatidylglycerophosphate synthase complement(3056548..3057396) Streptomyces avermitilis MA-4680 1210449 NP_823684.1 CDS SAV_2508 NC_003155.4 3057393 3058880 R PF00919: Uncharacterized protein family UPF0004; hypothetical protein complement(3057393..3058880) Streptomyces avermitilis MA-4680 1213833 NP_823685.1 CDS SAV_2509 NC_003155.4 3058992 3059888 R hypothetical protein complement(3058992..3059888) Streptomyces avermitilis MA-4680 1213834 NP_823686.1 CDS ftsK NC_003155.4 3060126 3062879 R DNA translocase FtsK complement(3060126..3062879) Streptomyces avermitilis MA-4680 1210450 NP_823687.1 CDS SAV_2511 NC_003155.4 3062987 3063673 R two-component system response regulator complement(3062987..3063673) Streptomyces avermitilis MA-4680 1213835 NP_823688.1 CDS SAV_2512 NC_003155.4 3063948 3069437 R two-component system sensor kinase complement(3063948..3069437) Streptomyces avermitilis MA-4680 1213836 NP_823689.1 CDS prpM2 NC_003155.4 3069826 3072573 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 3069826..3072573 Streptomyces avermitilis MA-4680 1213837 NP_823690.1 CDS SAV_2514 NC_003155.4 3072791 3073468 R PF01041: DegT/DnrJ/EryC1/StrS aminotransferase family; hypothetical protein complement(3072791..3073468) Streptomyces avermitilis MA-4680 1213838 NP_823691.1 CDS SAV_2515 NC_003155.4 3079351 3081036 R PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase superfamily hydrolase complement(3079351..3081036) Streptomyces avermitilis MA-4680 1213839 NP_823692.1 CDS dapA NC_003155.4 3081165 3082064 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(3081165..3082064) Streptomyces avermitilis MA-4680 1210455 NP_823693.1 CDS thyX NC_003155.4 3082295 3083035 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(3082295..3083035) Streptomyces avermitilis MA-4680 1210456 NP_823694.1 CDS SAV_2518 NC_003155.4 3083239 3083478 D hypothetical protein 3083239..3083478 Streptomyces avermitilis MA-4680 1213840 NP_823695.1 CDS SAV_2519 NC_003155.4 3083604 3084161 D hypothetical protein 3083604..3084161 Streptomyces avermitilis MA-4680 1213841 NP_823696.1 CDS SAV_2520 NC_003155.4 3084239 3084691 R PF00515: TPR Domain; hypothetical protein complement(3084239..3084691) Streptomyces avermitilis MA-4680 1213842 NP_823697.1 CDS dapB NC_003155.4 3084697 3085449 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(3084697..3085449) Streptomyces avermitilis MA-4680 1210457 NP_823698.1 CDS SAV_2522 NC_003155.4 3085474 3086853 R PF05193: Peptidase M16 inactive domain; protease complement(3085474..3086853) Streptomyces avermitilis MA-4680 1213843 NP_823699.1 CDS pnp NC_003155.4 3086850 3089066 R polynucleotide phosphorylase/polyadenylase complement(3086850..3089066) Streptomyces avermitilis MA-4680 1210458 NP_823700.1 CDS rpsO NC_003155.4 3089414 3089701 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3089414..3089701) Streptomyces avermitilis MA-4680 1210459 NP_823701.1 CDS SAV_2525 NC_003155.4 3089920 3091380 R PF01011: PQQ enzyme repeat; hypothetical protein complement(3089920..3091380) Streptomyces avermitilis MA-4680 1213844 NP_823702.1 CDS SAV_2526 NC_003155.4 3091623 3093125 R PF01011: PQQ enzyme repeat; hypothetical protein complement(3091623..3093125) Streptomyces avermitilis MA-4680 1213845 NP_823703.1 CDS SAV_2527 NC_003155.4 3093280 3094788 R PF04600: Protein of unknown function (DUF571); hypothetical protein complement(3093280..3094788) Streptomyces avermitilis MA-4680 1213846 NP_823704.1 CDS SAV_2528 NC_003155.4 3095123 3099094 D FtsK/SpoIIIE family protein 3095123..3099094 Streptomyces avermitilis MA-4680 1213847 NP_823705.1 CDS bldB NC_003155.4 3099241 3099561 D BldB protein 3099241..3099561 Streptomyces avermitilis MA-4680 1210460 NP_823706.1 CDS SAV_2530 NC_003155.4 3099693 3100982 D hypothetical protein 3099693..3100982 Streptomyces avermitilis MA-4680 1213848 NP_823707.1 CDS SAV_2531 NC_003155.4 3101017 3102105 R hypothetical protein complement(3101017..3102105) Streptomyces avermitilis MA-4680 1213849 NP_823708.1 CDS SAV_2532 NC_003155.4 3102549 3102848 R PF06013: Proteins of 100 residues with WXG; hypothetical protein complement(3102549..3102848) Streptomyces avermitilis MA-4680 1213850 NP_823709.1 CDS SAV_2533 NC_003155.4 3102929 3103279 R hypothetical protein complement(3102929..3103279) Streptomyces avermitilis MA-4680 1213851 NP_823710.1 CDS SAV_2534 NC_003155.4 3103399 3104616 R PF00082: Subtilase family; serine protease complement(3103399..3104616) Streptomyces avermitilis MA-4680 1213852 NP_823711.1 CDS SAV_2535 NC_003155.4 3104717 3106504 R hypothetical protein complement(3104717..3106504) Streptomyces avermitilis MA-4680 1213853 NP_823712.1 CDS SAV_2536 NC_003155.4 3106501 3107028 R hypothetical protein complement(3106501..3107028) Streptomyces avermitilis MA-4680 1213854 NP_823713.1 CDS SAV_2537 NC_003155.4 3107404 3107856 D hypothetical protein 3107404..3107856 Streptomyces avermitilis MA-4680 1213855 NP_823714.1 CDS SAV_2538 NC_003155.4 3107861 3110161 D hypothetical protein 3107861..3110161 Streptomyces avermitilis MA-4680 1213856 NP_823715.1 CDS SAV_2539 NC_003155.4 3111308 3111895 R hypothetical protein complement(3111308..3111895) Streptomyces avermitilis MA-4680 1213857 NP_823716.1 CDS SAV_2540 NC_003155.4 3111892 3113190 R PF00082: Subtilase family; serine protease complement(3111892..3113190) Streptomyces avermitilis MA-4680 1213858 NP_823717.1 CDS SAV_2541 NC_003155.4 3113221 3114744 R PF05108: Protein of unknown function (DUF690); hypothetical protein complement(3113221..3114744) Streptomyces avermitilis MA-4680 1213859 NP_823718.1 CDS SAV_2542 NC_003155.4 3114971 3116308 D hypothetical protein 3114971..3116308 Streptomyces avermitilis MA-4680 1213860 NP_823719.1 CDS SAV_2543 NC_003155.4 3116308 3117111 D hypothetical protein 3116308..3117111 Streptomyces avermitilis MA-4680 1213861 NP_823720.1 CDS SAV_2544 NC_003155.4 3118702 3121134 D PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; hypothetical protein 3118702..3121134 Streptomyces avermitilis MA-4680 1213862 NP_823721.1 CDS SAV_2545 NC_003155.4 3121210 3122004 R hypothetical protein complement(3121210..3122004) Streptomyces avermitilis MA-4680 1213863 NP_823722.1 CDS ribF NC_003155.4 3122078 3123031 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(3122078..3123031) Streptomyces avermitilis MA-4680 1210461 NP_823723.1 CDS SAV_2547 NC_003155.4 3123180 3126779 R hypothetical protein complement(3123180..3126779) Streptomyces avermitilis MA-4680 1213864 NP_823724.1 CDS truB NC_003155.4 3127064 3127969 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3127064..3127969) Streptomyces avermitilis MA-4680 1210462 NP_823725.1 CDS rbfA NC_003155.4 3127966 3128439 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3127966..3128439) Streptomyces avermitilis MA-4680 1210463 NP_823726.1 CDS SAV_2550 NC_003155.4 3128474 3128767 R PF04456: Protein of unknown function (DUF503); hypothetical protein complement(3128474..3128767) Streptomyces avermitilis MA-4680 1213865 NP_823727.1 CDS infB NC_003155.4 3128920 3132060 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3128920..3132060) Streptomyces avermitilis MA-4680 1210464 NP_823728.1 CDS SAV_2552 NC_003155.4 3132208 3132501 R PF04296: Protein of unknown function (DUF448); hypothetical protein complement(3132208..3132501) Streptomyces avermitilis MA-4680 1213866 NP_823729.1 CDS nusA NC_003155.4 3132616 3133602 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3132616..3133602) Streptomyces avermitilis MA-4680 1210465 NP_823730.1 CDS SAV_2554 NC_003155.4 3133605 3134114 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3133605..3134114) Streptomyces avermitilis MA-4680 1213867 NP_823731.1 CDS SAV_2555 NC_003155.4 3134389 3135087 D hypothetical protein 3134389..3135087 Streptomyces avermitilis MA-4680 1213868 NP_823732.1 CDS SAV_2556 NC_003155.4 3135084 3135587 D hypothetical protein 3135084..3135587 Streptomyces avermitilis MA-4680 1213869 NP_823733.1 CDS aph2 NC_003155.4 3135663 3136565 D homology to streptomycin 6-phosphotransferase; phosphotransferase 3135663..3136565 Streptomyces avermitilis MA-4680 1210466 NP_823734.1 CDS proS1 NC_003155.4 3136889 3138583 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(3136889..3138583) Streptomyces avermitilis MA-4680 1210467 NP_823735.1 CDS SAV_2559 NC_003155.4 3138697 3139266 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(3138697..3139266) Streptomyces avermitilis MA-4680 1213870 NP_823736.1 CDS SAV_2560 NC_003155.4 3139424 3140311 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(3139424..3140311) Streptomyces avermitilis MA-4680 1213871 NP_823737.1 CDS ispG NC_003155.4 3140456 3141613 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(3140456..3141613) Streptomyces avermitilis MA-4680 1210468 NP_823738.1 CDS SAV_2562 NC_003155.4 3141782 3143086 R PF02163: Peptidase family M50; metalloprotease complement(3141782..3143086) Streptomyces avermitilis MA-4680 1213872 NP_823739.1 CDS dxr NC_003155.4 3143083 3144267 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(3143083..3144267) Streptomyces avermitilis MA-4680 1210469 NP_823740.1 CDS SAV_2564 NC_003155.4 3144529 3144978 D PF00932: Intermediate filament tail domain; protein 3144529..3144978 Streptomyces avermitilis MA-4680 1213873 NP_823741.1 CDS secA2 NC_003155.4 3144985 3147747 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(3144985..3147747) Streptomyces avermitilis MA-4680 1210470 NP_823742.1 CDS SAV_2566 NC_003155.4 3147845 3148330 R hypothetical protein complement(3147845..3148330) Streptomyces avermitilis MA-4680 1213874 NP_823743.1 CDS fadE11 NC_003155.4 3148433 3150373 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(3148433..3150373) Streptomyces avermitilis MA-4680 1210471 NP_823744.1 CDS celA4 NC_003155.4 3150501 3151310 R endo-1,4-beta-glucanase complement(3150501..3151310) Streptomyces avermitilis MA-4680 1210472 NP_823745.1 CDS SAV_2569 NC_003155.4 3151535 3152548 D LacI family transcriptional regulator 3151535..3152548 Streptomyces avermitilis MA-4680 1213875 NP_823746.1 CDS SAV_2570 NC_003155.4 3152878 3154806 D PF01055: Glycosyl hydrolases family 31; glycosyl hydrolase 3152878..3154806 Streptomyces avermitilis MA-4680 1213876 NP_823747.1 CDS SAV_2571 NC_003155.4 3154862 3155575 R PF01670: Glycosyl hydrolase family 12; hypothetical protein complement(3154862..3155575) Streptomyces avermitilis MA-4680 1213877 NP_823748.1 CDS SAV_2572 NC_003155.4 3155611 3157809 R hypothetical protein complement(3155611..3157809) Streptomyces avermitilis MA-4680 1213878 NP_823749.1 CDS bga6 NC_003155.4 3157806 3159785 R beta-galactosidase complement(3157806..3159785) Streptomyces avermitilis MA-4680 1210473 NP_823750.1 CDS SAV_2574 NC_003155.4 3159785 3162004 R PF02012: BNR/Asp-box repeat; endo-1,4-beta-glucanase complement(3159785..3162004) Streptomyces avermitilis MA-4680 1213879 NP_823751.1 CDS SAV_2575 NC_003155.4 3162175 3163110 R ABC transporter permease complement(3162175..3163110) Streptomyces avermitilis MA-4680 1213880 NP_823752.1 CDS SAV_2576 NC_003155.4 3163107 3164192 R ABC transporter permease complement(3163107..3164192) Streptomyces avermitilis MA-4680 1213881 NP_823753.1 CDS lplA NC_003155.4 3164197 3165879 R multiple sugar ABC transporter substrate-binding protein complement(3164197..3165879) Streptomyces avermitilis MA-4680 1210474 NP_823754.1 CDS SAV_2578 NC_003155.4 3166246 3169110 D PF01915: Glycosyl hydrolase family 3 C terminal domain; sugar hydrolase 3166246..3169110 Streptomyces avermitilis MA-4680 1213882 NP_823755.1 CDS SAV_2579 NC_003155.4 3169298 3170743 R aldehyde dehydrogenase complement(3169298..3170743) Streptomyces avermitilis MA-4680 1213883 NP_823756.1 CDS SAV_2580 NC_003155.4 3170953 3172035 R frameshift; regulatory protein complement(3170953..3172035) Streptomyces avermitilis MA-4680 1213884 NP_823757.1 CDS SAV_2581 NC_003155.4 3171843 3172622 R frameshift; regulatory protein complement(3171843..3172622) Streptomyces avermitilis MA-4680 1213885 NP_823758.1 CDS SAV_2582 NC_003155.4 3172738 3175179 R ATP/GTP-binding protein complement(3172738..3175179) Streptomyces avermitilis MA-4680 1213886 NP_823759.1 CDS gabT NC_003155.4 3175462 3176796 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3175462..3176796 Streptomyces avermitilis MA-4680 1210475 NP_823760.1 CDS SAV_2584 NC_003155.4 3176974 3177798 D PF01569: PAP2 superfamily; hypothetical protein 3176974..3177798 Streptomyces avermitilis MA-4680 1213887 NP_823761.1 CDS chiB NC_003155.4 3177737 3179566 R chitinase B complement(3177737..3179566) Streptomyces avermitilis MA-4680 1210476 NP_823762.1 CDS SAV_2587 NC_003155.4 3179635 3181170 R frameshift; hypothetical protein complement(3179635..3181170) Streptomyces avermitilis MA-4680 1213888 NP_823763.1 CDS SAV_2586 NC_003155.4 3179751 3179960 R frameshift; hypothetical protein complement(3179751..3179960) Streptomyces avermitilis MA-4680 1213889 NP_823764.1 CDS SAV_2588 NC_003155.4 3181199 3181999 R PF00528: Binding-protein-dependent transport system inner membrane component; polyamine ABC transporter permease complement(3181199..3181999) Streptomyces avermitilis MA-4680 1213890 NP_823765.1 CDS SAV_2589 NC_003155.4 3182000 3182944 R polyamine ABC transporter permease complement(3182000..3182944) Streptomyces avermitilis MA-4680 1213891 NP_823766.1 CDS SAV_2590 NC_003155.4 3182941 3184104 R polyamine ABC transporter ATP-binding protein complement(3182941..3184104) Streptomyces avermitilis MA-4680 1213892 NP_823767.1 CDS SAV_2591 NC_003155.4 3184101 3185348 R polyamine ABC transporter substrate-binding protein complement(3184101..3185348) Streptomyces avermitilis MA-4680 1213893 NP_823768.1 CDS SAV_2592 NC_003155.4 3185428 3186951 R catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase complement(3185428..3186951) Streptomyces avermitilis MA-4680 1213894 NP_823769.1 CDS SAV_2593 NC_003155.4 3187135 3187722 D hypothetical protein 3187135..3187722 Streptomyces avermitilis MA-4680 1213895 NP_823770.1 CDS SAV_2594 NC_003155.4 3187745 3188071 R hypothetical protein complement(3187745..3188071) Streptomyces avermitilis MA-4680 1213896 NP_823771.1 CDS add2 NC_003155.4 3189222 3190298 D catalyzes the formation of inosine from adenosine; adenosine deaminase 3189222..3190298 Streptomyces avermitilis MA-4680 1210477 NP_823772.1 CDS glpQ1 NC_003155.4 3190331 3191011 D glycerophosphoryl diester phosphodiesterase 3190331..3191011 Streptomyces avermitilis MA-4680 1210478 NP_823773.1 CDS sig20 NC_003155.4 3191131 3193035 R ECF subfamily RNA polymerase sigma factor complement(3191131..3193035) Streptomyces avermitilis MA-4680 1210479 NP_823774.1 CDS SAV_2598 NC_003155.4 3193078 3193662 R hypothetical protein complement(3193078..3193662) Streptomyces avermitilis MA-4680 1213897 NP_823775.1 CDS SAV_2599 NC_003155.4 3193693 3194193 D hypothetical protein 3193693..3194193 Streptomyces avermitilis MA-4680 1213898 NP_823776.1 CDS clpC1 NC_003155.4 3194289 3196817 D PF07724: ATPase family associated with various cellular activities (AAA); ATP-dependent Clp protease 3194289..3196817 Streptomyces avermitilis MA-4680 1210480 NP_823777.1 CDS SAV_2601 NC_003155.4 3197051 3197644 D PadR-like family transcriptional regulator 3197051..3197644 Streptomyces avermitilis MA-4680 1213899 NP_823778.1 CDS SAV_2602 NC_003155.4 3197875 3198312 D PF02566: OsmC-like protein; hypothetical protein 3197875..3198312 Streptomyces avermitilis MA-4680 1213900 NP_823779.1 CDS SAV_2603 NC_003155.4 3198583 3199818 R PF07690: Major Facilitator Superfamily; multi-drug efflux transporter complement(3198583..3199818) Streptomyces avermitilis MA-4680 1213901 NP_823780.1 CDS SAV_2604 NC_003155.4 3199977 3202772 D protein 3199977..3202772 Streptomyces avermitilis MA-4680 1213902 NP_823781.1 CDS SAV_2605 NC_003155.4 3202942 3203868 D PF03060: 2-nitropropane dioxygenase; dioxygenase 3202942..3203868 Streptomyces avermitilis MA-4680 1213903 NP_823782.1 CDS SAV_2606 NC_003155.4 3204071 3205114 R sulfate transporter complement(3204071..3205114) Streptomyces avermitilis MA-4680 1213904 NP_823783.1 CDS SAV_2607 NC_003155.4 3205645 3205962 D frameshift; transposase 3205645..3205962 Streptomyces avermitilis MA-4680 1213905 NP_823784.1 CDS SAV_2608 NC_003155.4 3205662 3206138 D frameshift; transposase 3205662..3206138 Streptomyces avermitilis MA-4680 1213906 NP_823785.1 CDS SAV_2609 NC_003155.4 3206678 3207868 R ABC transporter substrate-binding protein complement(3206678..3207868) Streptomyces avermitilis MA-4680 1213907 NP_823786.1 CDS SAV_2610 NC_003155.4 3208119 3209558 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(3208119..3209558) Streptomyces avermitilis MA-4680 1213908 NP_823787.1 CDS SAV_2611 NC_003155.4 3209748 3210248 D transcription regulator AsnC 3209748..3210248 Streptomyces avermitilis MA-4680 1213909 NP_823788.1 CDS SAV_2612 NC_003155.4 3210233 3211612 D hypothetical protein 3210233..3211612 Streptomyces avermitilis MA-4680 1213910 NP_823789.1 CDS SAV_2613 NC_003155.4 3211871 3212608 D ABC transporter ATP-binding protein 3211871..3212608 Streptomyces avermitilis MA-4680 1213911 NP_823790.1 CDS SAV_2614 NC_003155.4 3212590 3213984 D hypothetical protein 3212590..3213984 Streptomyces avermitilis MA-4680 1213912 NP_823791.1 CDS SAV_2615 NC_003155.4 3214075 3214482 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 3214075..3214482 Streptomyces avermitilis MA-4680 1213913 NP_823792.1 CDS SAV_2616 NC_003155.4 3214509 3215627 D PF03641: Possible lysine decarboxylase; hypothetical protein 3214509..3215627 Streptomyces avermitilis MA-4680 1213914 NP_823793.1 CDS SAV_2617 NC_003155.4 3215775 3216449 D hypothetical protein 3215775..3216449 Streptomyces avermitilis MA-4680 1213915 NP_823794.1 CDS SAV_2618 NC_003155.4 3216570 3217607 R ABC transporter ATP-binding protein complement(3216570..3217607) Streptomyces avermitilis MA-4680 1213916 NP_823795.1 CDS SAV_2619 NC_003155.4 3217608 3219308 R hypothetical protein complement(3217608..3219308) Streptomyces avermitilis MA-4680 1213917 NP_823796.1 CDS SAV_2620 NC_003155.4 3219272 3220357 R ABC transporter substrate-binding protein complement(3219272..3220357) Streptomyces avermitilis MA-4680 1213918 NP_823797.1 CDS SAV_2621 NC_003155.4 3220568 3221674 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(3220568..3221674) Streptomyces avermitilis MA-4680 1213919 NP_823798.1 CDS SAV_2622 NC_003155.4 3221960 3222370 R hypothetical protein complement(3221960..3222370) Streptomyces avermitilis MA-4680 1213920 NP_823799.1 CDS cdsA NC_003155.4 3222628 3223806 R phosphatidate cytidylyltransferase complement(3222628..3223806) Streptomyces avermitilis MA-4680 1210481 NP_823800.1 CDS frr NC_003155.4 3223806 3224363 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(3223806..3224363) Streptomyces avermitilis MA-4680 1210482 NP_823801.1 CDS pyrH NC_003155.4 3224517 3225275 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(3224517..3225275) Streptomyces avermitilis MA-4680 1210483 NP_823802.1 CDS tsf NC_003155.4 3225476 3226312 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(3225476..3226312) Streptomyces avermitilis MA-4680 1210484 NP_823803.1 CDS rpsB NC_003155.4 3226409 3227335 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(3226409..3227335) Streptomyces avermitilis MA-4680 1210485 NP_823804.1 CDS SAV_2628 NC_003155.4 3227598 3228296 D PF01551: Peptidase family M23; peptidase 3227598..3228296 Streptomyces avermitilis MA-4680 1213921 NP_823805.1 CDS SAV_2629 NC_003155.4 3228411 3228950 R TetR family transcriptional regulator complement(3228411..3228950) Streptomyces avermitilis MA-4680 1213922 NP_823806.1 CDS whiG NC_003155.4 3229155 3229997 R involved in the initiation of sporulation and glycogen biosynthesis; RNA polymerase sigma factor WhiG complement(3229155..3229997) Streptomyces avermitilis MA-4680 1210486 NP_823807.1 CDS SAV_2631 NC_003155.4 3230270 3231415 R DNA processing Smf-family protein complement(3230270..3231415) Streptomyces avermitilis MA-4680 1213923 NP_823808.1 CDS SAV_2632 NC_003155.4 3231412 3233037 R magnesium chelatase complement(3231412..3233037) Streptomyces avermitilis MA-4680 1213924 NP_823809.1 CDS SAV_2633 NC_003155.4 3233037 3233579 R PF02021: Uncharacterised protein family UPF0102; hypothetical protein complement(3233037..3233579) Streptomyces avermitilis MA-4680 1213925 NP_823810.1 CDS SAV_2634 NC_003155.4 3233591 3233899 R hypothetical protein complement(3233591..3233899) Streptomyces avermitilis MA-4680 1213926 NP_823811.1 CDS SAV_2635 NC_003155.4 3234017 3234544 R PF00293: NUDIX domain; MutT/NUDIX family hydrolase complement(3234017..3234544) Streptomyces avermitilis MA-4680 1213927 NP_823812.1 CDS SAV_2636 NC_003155.4 3234534 3235277 R PF00717: Peptidase S24-like; signal peptidase complement(3234534..3235277) Streptomyces avermitilis MA-4680 1213928 NP_823813.1 CDS SAV_2637 NC_003155.4 3235357 3236232 R PF00717: Peptidase S24-like; signal peptidase complement(3235357..3236232) Streptomyces avermitilis MA-4680 1213929 NP_823814.1 CDS SAV_2638 NC_003155.4 3236204 3237286 R PF00717: Peptidase S24-like; signal peptidase complement(3236204..3237286) Streptomyces avermitilis MA-4680 1213930 NP_823815.1 CDS SAV_2639 NC_003155.4 3237279 3237995 R PF00717: Peptidase S24-like; signal peptidase complement(3237279..3237995) Streptomyces avermitilis MA-4680 1213931 NP_823816.1 CDS rplS NC_003155.4 3238041 3238391 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(3238041..3238391) Streptomyces avermitilis MA-4680 1210487 NP_823817.1 CDS trmD NC_003155.4 3238527 3239375 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(3238527..3239375) Streptomyces avermitilis MA-4680 1210488 NP_823818.1 CDS rimM NC_003155.4 3239375 3239935 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(3239375..3239935) Streptomyces avermitilis MA-4680 1210489 NP_823819.1 CDS SAV_2643 NC_003155.4 3240044 3240283 R hypothetical protein complement(3240044..3240283) Streptomyces avermitilis MA-4680 1213932 NP_823820.1 CDS rpsP NC_003155.4 3240286 3240714 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(3240286..3240714) Streptomyces avermitilis MA-4680 1210490 NP_823821.1 CDS SAV_2645 NC_003155.4 3240997 3241593 R hypothetical protein complement(3240997..3241593) Streptomyces avermitilis MA-4680 1213933 NP_823822.1 CDS proS2 NC_003155.4 3241855 3243270 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(3241855..3243270) Streptomyces avermitilis MA-4680 1210491 NP_823823.1 CDS SAV_2647 NC_003155.4 3243503 3244366 D hypothetical protein 3243503..3244366 Streptomyces avermitilis MA-4680 1213934 NP_823824.1 CDS ffh NC_003155.4 3244452 3246002 R signal recognition particle complement(3244452..3246002) Streptomyces avermitilis MA-4680 1210492 NP_823825.2 CDS glnD NC_003155.4 3246143 3248602 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK; PII uridylyl-transferase complement(3246143..3248602) Streptomyces avermitilis MA-4680 1210493 NP_823826.1 CDS glnB1 NC_003155.4 3248625 3248963 R regulatory protein for glutamine synthetase; glnB-homolog; nitrogen regulatory protein P-II complement(3248625..3248963) Streptomyces avermitilis MA-4680 1210494 NP_823827.1 CDS amtB1 NC_003155.4 3248960 3250300 R ammonium transporter complement(3248960..3250300) Streptomyces avermitilis MA-4680 1213935 NP_823828.1 CDS SAV_2652 NC_003155.4 3250639 3252114 R regulatory protein complement(3250639..3252114) Streptomyces avermitilis MA-4680 1213936 NP_823829.1 CDS SAV_2653 NC_003155.4 3252563 3253225 D hypothetical protein 3252563..3253225 Streptomyces avermitilis MA-4680 1213937 NP_823830.1 CDS ftsY NC_003155.4 3253315 3254544 R signal recognition particle complement(3253315..3254544) Streptomyces avermitilis MA-4680 1210495 NP_823831.1 CDS SAV_2655 NC_003155.4 3254633 3256105 D allantoin permease 3254633..3256105 Streptomyces avermitilis MA-4680 1213938 NP_823832.1 CDS SAV_2656 NC_003155.4 3256152 3257132 D PF00296: Luciferase-like monooxygenase; hypothetical protein 3256152..3257132 Streptomyces avermitilis MA-4680 1213939 NP_823833.1 CDS araE NC_003155.4 3257219 3258631 R L-arabinose permease complement(3257219..3258631) Streptomyces avermitilis MA-4680 1210496 NP_823834.1 CDS smc NC_003155.4 3258894 3262502 R PF02483: SMC family, C-terminal domain; chromosome segregation protein complement(3258894..3262502) Streptomyces avermitilis MA-4680 1210497 NP_823835.1 CDS acyP NC_003155.4 3263295 3263576 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(3263295..3263576) Streptomyces avermitilis MA-4680 1210498 NP_823836.1 CDS SAV_2660 NC_003155.4 3263727 3264662 D PF00188: SCP-like extracellular protein; hypothetical protein 3263727..3264662 Streptomyces avermitilis MA-4680 1213940 NP_823837.1 CDS SAV_2661 NC_003155.4 3264841 3265464 R PF00258: Flavodoxin; hypothetical protein complement(3264841..3265464) Streptomyces avermitilis MA-4680 1213941 NP_823838.1 CDS SAV_2662 NC_003155.4 3265560 3265973 D PF01638: Transcriptional regulator; transcriptional regulator 3265560..3265973 Streptomyces avermitilis MA-4680 1213942 NP_823839.1 CDS SAV_2663 NC_003155.4 3265995 3267308 R PF00144: Beta-lactamase; beta-lactamase complement(3265995..3267308) Streptomyces avermitilis MA-4680 1213943 NP_823840.1 CDS mutM1 NC_003155.4 3267410 3268270 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(3267410..3268270) Streptomyces avermitilis MA-4680 1210499 NP_823841.1 CDS rnc NC_003155.4 3268331 3269161 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(3268331..3269161) Streptomyces avermitilis MA-4680 1210500 NP_823842.1 CDS rpmF NC_003155.4 3269181 3269354 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(3269181..3269354) Streptomyces avermitilis MA-4680 1210501 NP_823843.1 CDS SAV_2667 NC_003155.4 3269357 3270010 R PF02620: Uncharacterized ACR, COG1399; hypothetical protein complement(3269357..3270010) Streptomyces avermitilis MA-4680 1213944 NP_823844.1 CDS SAV_2668 NC_003155.4 3270151 3271242 R PF05227: CHASE3 domain; hypothetical protein complement(3270151..3271242) Streptomyces avermitilis MA-4680 1213945 NP_823845.1 CDS coaD NC_003155.4 3271392 3271871 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(3271392..3271871) Streptomyces avermitilis MA-4680 1210502 NP_823846.1 CDS SAV_2670 NC_003155.4 3271898 3272485 R RNA methylase complement(3271898..3272485) Streptomyces avermitilis MA-4680 1213946 NP_823847.1 CDS recG NC_003155.4 3272525 3275752 R PF00271: Helicase conserved C-terminal domain; ATP-dependent DNA helicase complement(3272525..3275752) Streptomyces avermitilis MA-4680 1210503 NP_823848.1 CDS htpG NC_003155.4 3276139 3277977 D HSP90 family protein 3276139..3277977 Streptomyces avermitilis MA-4680 1210504 NP_823849.1 CDS SAV_2673 NC_003155.4 3277935 3280910 D PF04012: PspA/IM30 family; hypothetical protein 3277935..3280910 Streptomyces avermitilis MA-4680 1213947 NP_823850.1 CDS dak3 NC_003155.4 3281061 3282776 R dihydroxyacetone kinase complement(3281061..3282776) Streptomyces avermitilis MA-4680 1210505 NP_823851.1 CDS rpmB NC_003155.4 3283164 3283349 D required for 70S ribosome assembly; 50S ribosomal protein L28 3283164..3283349 Streptomyces avermitilis MA-4680 1210506 NP_823852.1 CDS thiL NC_003155.4 3283489 3284451 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(3283489..3284451) Streptomyces avermitilis MA-4680 1210507 NP_823853.1 CDS SAV_2677 NC_003155.4 3284697 3284930 D PF01037: AsnC family; hypothetical protein 3284697..3284930 Streptomyces avermitilis MA-4680 1213948 NP_823854.1 CDS SAV_2678 NC_003155.4 3284951 3285442 D hypothetical protein 3284951..3285442 Streptomyces avermitilis MA-4680 1213949 NP_823855.1 CDS ddl NC_003155.4 3285458 3286615 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(3285458..3286615) Streptomyces avermitilis MA-4680 1210508 NP_823856.1 CDS gpsA NC_003155.4 3286753 3287763 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(3286753..3287763) Streptomyces avermitilis MA-4680 1210509 NP_823857.1 CDS plsC2 NC_003155.4 3287760 3288560 R 1-acylglycerol-3-phosphate O-acyltransferase complement(3287760..3288560) Streptomyces avermitilis MA-4680 1210510 NP_823858.1 CDS SAV_2682 NC_003155.4 3288705 3289355 D PF01983: Protein of unknown function DUF121; hypothetical protein 3288705..3289355 Streptomyces avermitilis MA-4680 1213950 NP_823859.1 CDS SAV_2683 NC_003155.4 3289365 3289568 D hypothetical protein 3289365..3289568 Streptomyces avermitilis MA-4680 1213951 NP_823860.1 CDS SAV_2684 NC_003155.4 3289655 3290308 R PF00216: Bacterial DNA-binding protein; histone-like DNA-binding protein complement(3289655..3290308) Streptomyces avermitilis MA-4680 1213952 NP_823861.1 CDS leuD NC_003155.4 3290964 3291557 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(3290964..3291557) Streptomyces avermitilis MA-4680 1210511 NP_823862.1 CDS leuC NC_003155.4 3291564 3292997 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(3291564..3292997) Streptomyces avermitilis MA-4680 1210512 NP_823863.1 CDS SAV_2687 NC_003155.4 3293189 3293905 D IclR family transcriptional regulator 3293189..3293905 Streptomyces avermitilis MA-4680 1213953 NP_823864.1 CDS SAV_2688 NC_003155.4 3293979 3294476 R hypothetical protein complement(3293979..3294476) Streptomyces avermitilis MA-4680 1213954 NP_823865.1 CDS SAV_2689 NC_003155.4 3294558 3295202 D transcriptional regulator 3294558..3295202 Streptomyces avermitilis MA-4680 1213955 NP_823866.1 CDS SAV_2690 NC_003155.4 3295851 3296987 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(3295851..3296987) Streptomyces avermitilis MA-4680 1213956 NP_823867.1 CDS gltX NC_003155.4 3297120 3298634 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(3297120..3298634) Streptomyces avermitilis MA-4680 1210518 NP_823868.1 CDS SAV_2692 NC_003155.4 3298627 3299403 R PF01557: Fumarylacetoacetate (FAA) hydrolase family; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase complement(3298627..3299403) Streptomyces avermitilis MA-4680 1213957 NP_823869.1 CDS SAV_2693 NC_003155.4 3299569 3299742 R hypothetical protein complement(3299569..3299742) Streptomyces avermitilis MA-4680 1213958 NP_823870.1 CDS cvnA6 NC_003155.4 3300359 3304195 D multi-component regulatory system-6; sensor-like histidine kinase 3300359..3304195 Streptomyces avermitilis MA-4680 1210519 NP_823871.1 CDS cvnB6 NC_003155.4 3304205 3304618 D multi-component regulatory system-6, PF03259: Roadblock/LC7 domain; hypothetical protein 3304205..3304618 Streptomyces avermitilis MA-4680 1210520 NP_823872.1 CDS cvnC6 NC_003155.4 3304730 3305128 D multi-component regulatory system-6, PF05331: Protein of unknown function (DUF742); hypothetical protein 3304730..3305128 Streptomyces avermitilis MA-4680 1210521 NP_823873.1 CDS cvnD6 NC_003155.4 3305109 3305687 D multi-component regulatory system-6; ATP/GTP-binding protein 3305109..3305687 Streptomyces avermitilis MA-4680 1210522 NP_823874.1 CDS cvnA7 NC_003155.4 3306085 3309330 D multi-component regulatory system-7; sensor-like histidine kinase 3306085..3309330 Streptomyces avermitilis MA-4680 1210523 NP_823875.1 CDS cvnB7 NC_003155.4 3309341 3309754 D multi-component regulatory system-7, PF03259: Roadblock/LC7 domain; hypothetical protein 3309341..3309754 Streptomyces avermitilis MA-4680 1210524 NP_823876.1 CDS cvnC7 NC_003155.4 3309851 3310435 D multi-component regulatory system-7, PF05331: Protein of unknown function (DUF742); hypothetical protein 3309851..3310435 Streptomyces avermitilis MA-4680 1210525 NP_823877.1 CDS cvnD7 NC_003155.4 3310473 3310997 D multi-component regulatory system-7; ATP/GTP-binding protein 3310473..3310997 Streptomyces avermitilis MA-4680 1210526 NP_823878.1 CDS SAV_2702 NC_003155.4 3311416 3311610 R hypothetical protein complement(3311416..3311610) Streptomyces avermitilis MA-4680 1213959 NP_823879.1 CDS mmdA2 NC_003155.4 3311668 3313263 R PF01039: Carboxyl transferase domain; methylmalonyl-CoA decarboxylase alpha subunit complement(3311668..3313263) Streptomyces avermitilis MA-4680 1210527 NP_823880.1 CDS SAV_2704 NC_003155.4 3313418 3315745 R PF02278: Polysaccharide lyase family 8, super-sandwich domain; polysaccharide lyase (hyaluronidase) complement(3313418..3315745) Streptomyces avermitilis MA-4680 1213960 NP_823881.1 CDS SAV_2705 NC_003155.4 3315813 3316322 R hypothetical protein complement(3315813..3316322) Streptomyces avermitilis MA-4680 1213961 NP_823882.1 CDS SAV_2706 NC_003155.4 3316560 3317180 D PF04264: YceI like family; hypothetical protein 3316560..3317180 Streptomyces avermitilis MA-4680 1213962 NP_823883.1 CDS SAV_2707 NC_003155.4 3317290 3318660 R hypothetical protein complement(3317290..3318660) Streptomyces avermitilis MA-4680 1213963 NP_823884.1 CDS SAV_2708 NC_003155.4 3318766 3321801 R PF00933: Glycosyl hydrolase family 3 N terminal domain; glycosyl hydrolase complement(3318766..3321801) Streptomyces avermitilis MA-4680 1213964 NP_823885.1 CDS SAV_2709 NC_003155.4 3321963 3323906 D PF00652: QXW lectin repeat; glycosyl hydrolase 3321963..3323906 Streptomyces avermitilis MA-4680 1213965 NP_823886.1 CDS leuA1 NC_003155.4 3323914 3325518 R catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA; putative alpha-isopropylmalate/homocitrate synthase family transferase complement(3323914..3325518) Streptomyces avermitilis MA-4680 1210528 NP_823887.1 CDS SAV_2711 NC_003155.4 3325807 3327138 R PF00083: Sugar (and other) transporter; transporter complement(3325807..3327138) Streptomyces avermitilis MA-4680 1213966 NP_823888.1 CDS SAV_2712 NC_003155.4 3327202 3328545 R PF07676: WD40-like Beta Propeller Repeat; hypothetical protein complement(3327202..3328545) Streptomyces avermitilis MA-4680 1213967 NP_823889.1 CDS SAV_2713 NC_003155.4 3328981 3329601 R TetR family transcriptional regulator complement(3328981..3329601) Streptomyces avermitilis MA-4680 1213968 NP_823890.1 CDS aguA NC_003155.4 3329613 3330653 R agmatine deiminase complement(3329613..3330653) Streptomyces avermitilis MA-4680 1210529 NP_823891.1 CDS ureC NC_003155.4 3330663 3332333 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(3330663..3332333) Streptomyces avermitilis MA-4680 1210530 NP_823892.1 CDS ureAB NC_003155.4 3332330 3333013 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; bifunctional urease subunit gamma/beta complement(3332330..3333013) Streptomyces avermitilis MA-4680 1210531 NP_823893.1 CDS ilvE NC_003155.4 3333251 3334339 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(3333251..3334339) Streptomyces avermitilis MA-4680 1210532 NP_823894.1 CDS leuB NC_003155.4 3334606 3335649 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(3334606..3335649) Streptomyces avermitilis MA-4680 1210533 NP_823895.1 CDS ppe1 NC_003155.4 3335713 3337362 D phosphoesterase 3335713..3337362 Streptomyces avermitilis MA-4680 1213969 NP_823896.1 CDS SAV_2720 NC_003155.4 3337468 3337599 R hypothetical protein complement(3337468..3337599) Streptomyces avermitilis MA-4680 1213970 NP_823897.1 CDS aac1 NC_003155.4 3338018 3338587 R aminoglycoside 2'-N-acetyltransferase complement(3338018..3338587) Streptomyces avermitilis MA-4680 1210534 NP_823898.1 CDS SAV_2722 NC_003155.4 3338680 3339549 D PF00561: alpha/beta hydrolase fold; hydrolase 3338680..3339549 Streptomyces avermitilis MA-4680 1213971 NP_823899.1 CDS rocA NC_003155.4 3339557 3341188 R delta-1-pyrroline-5-carboxylate dehydrogenase complement(3339557..3341188) Streptomyces avermitilis MA-4680 1213972 NP_823900.1 CDS putA NC_003155.4 3341334 3342260 R proline dehydrogenase complement(3341334..3342260) Streptomyces avermitilis MA-4680 1210535 NP_823901.1 CDS SAV_2725 NC_003155.4 3342426 3343625 D transcriptional regulator 3342426..3343625 Streptomyces avermitilis MA-4680 1213973 NP_823902.1 CDS SAV_2726 NC_003155.4 3343682 3345178 R hypothetical protein complement(3343682..3345178) Streptomyces avermitilis MA-4680 1213974 NP_823903.1 CDS SAV_2727 NC_003155.4 3345291 3345881 R TetR family transcriptional regulator complement(3345291..3345881) Streptomyces avermitilis MA-4680 1213975 NP_823904.1 CDS SAV_2728 NC_003155.4 3346066 3347538 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 3346066..3347538 Streptomyces avermitilis MA-4680 1213976 NP_823905.1 CDS SAV_2729 NC_003155.4 3347780 3350794 D LuxR family transcriptional regulator 3347780..3350794 Streptomyces avermitilis MA-4680 1213977 NP_823906.1 CDS serA NC_003155.4 3350907 3352496 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3350907..3352496) Streptomyces avermitilis MA-4680 1210536 NP_823907.1 CDS ilvC NC_003155.4 3352764 3353765 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(3352764..3353765) Streptomyces avermitilis MA-4680 1210537 NP_823908.1 CDS ilvH NC_003155.4 3353885 3354412 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(3353885..3354412) Streptomyces avermitilis MA-4680 1210538 NP_823909.1 CDS ilvB1 NC_003155.4 3354433 3356283 R acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit complement(3354433..3356283) Streptomyces avermitilis MA-4680 1210539 NP_823910.1 CDS SAV_2734 NC_003155.4 3356515 3359652 R PF00563: EAL domain; integral membrane phosphodiesterase complement(3356515..3359652) Streptomyces avermitilis MA-4680 1213978 NP_823911.1 CDS SAV_2735 NC_003155.4 3359884 3360825 R PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; dehydrogenase complement(3359884..3360825) Streptomyces avermitilis MA-4680 1213979 NP_823912.1 CDS SAV_2736 NC_003155.4 3360967 3361899 D PF00248: Aldo/keto reductase family; oxidoreductase 3360967..3361899 Streptomyces avermitilis MA-4680 1213980 NP_823913.1 CDS SAV_2737 NC_003155.4 3362169 3363332 D PF05481: Mycobacterium 19 kDa lipoprotein antigen; oxidoreductase 3362169..3363332 Streptomyces avermitilis MA-4680 1213981 NP_823914.1 CDS SAV_2738 NC_003155.4 3363349 3363621 R hypothetical protein complement(3363349..3363621) Streptomyces avermitilis MA-4680 1213982 NP_823915.1 CDS SAV_2739 NC_003155.4 3363618 3367091 R LuxR family transcriptional regulator complement(3363618..3367091) Streptomyces avermitilis MA-4680 1213983 NP_823916.1 CDS SAV_2740 NC_003155.4 3367088 3367390 R hypothetical protein complement(3367088..3367390) Streptomyces avermitilis MA-4680 1213984 NP_823917.1 CDS SAV_2741 NC_003155.4 3367493 3368104 R hypothetical protein complement(3367493..3368104) Streptomyces avermitilis MA-4680 1213985 NP_823918.1 CDS SAV_2742 NC_003155.4 3368140 3368715 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(3368140..3368715) Streptomyces avermitilis MA-4680 1213986 NP_823919.1 CDS gatB NC_003155.4 3369059 3370576 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(3369059..3370576) Streptomyces avermitilis MA-4680 1210540 NP_823920.1 CDS SAV_2744 NC_003155.4 3370593 3370835 R hypothetical protein complement(3370593..3370835) Streptomyces avermitilis MA-4680 1213987 NP_823921.1 CDS gatA NC_003155.4 3370832 3372337 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(3370832..3372337) Streptomyces avermitilis MA-4680 1210541 NP_823922.1 CDS gatC NC_003155.4 3372343 3372639 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(3372343..3372639) Streptomyces avermitilis MA-4680 1210542 NP_823923.1 CDS SAV_2747 NC_003155.4 3372950 3375286 R PF00563: EAL domain; phosphodiesterase complement(3372950..3375286) Streptomyces avermitilis MA-4680 1213988 NP_823924.1 CDS ligA NC_003155.4 3375523 3377715 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(3375523..3377715) Streptomyces avermitilis MA-4680 1210543 NP_823925.1 CDS SAV_2749 NC_003155.4 3377731 3378738 R PF01717: Methionine synthase, vitamin-B12 independent; hypothetical protein complement(3377731..3378738) Streptomyces avermitilis MA-4680 1213989 NP_823926.1 CDS SAV_2750 NC_003155.4 3378845 3379543 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(3378845..3379543) Streptomyces avermitilis MA-4680 1213990 NP_823927.1 CDS SAV_2751 NC_003155.4 3379551 3380090 R PF03641: possible lysine decarboxylase; hypothetical protein complement(3379551..3380090) Streptomyces avermitilis MA-4680 1213991 NP_823928.1 CDS SAV_2752 NC_003155.4 3380142 3380465 D hypothetical protein 3380142..3380465 Streptomyces avermitilis MA-4680 1213992 NP_823929.1 CDS mnmA NC_003155.4 3380608 3381738 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(3380608..3381738) Streptomyces avermitilis MA-4680 1210544 NP_823930.1 CDS amiA1 NC_003155.4 3381799 3382455 D PF01510: N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 3381799..3382455 Streptomyces avermitilis MA-4680 1210545 NP_823931.1 CDS SAV_2755 NC_003155.4 3382802 3384250 D multicopper oxidase 3382802..3384250 Streptomyces avermitilis MA-4680 1213993 NP_823932.1 CDS SAV_2756 NC_003155.4 3384316 3385485 R pyridoxal-phosphate-dependent aminotransferase complement(3384316..3385485) Streptomyces avermitilis MA-4680 1213994 NP_823933.1 CDS SAV_2757 NC_003155.4 3385700 3385966 R hypothetical protein complement(3385700..3385966) Streptomyces avermitilis MA-4680 1213995 NP_823934.1 CDS SAV_2758 NC_003155.4 3386006 3386173 R hypothetical protein complement(3386006..3386173) Streptomyces avermitilis MA-4680 1213996 NP_823935.1 CDS SAV_2759 NC_003155.4 3386308 3386934 D TetR family transcriptional regulator 3386308..3386934 Streptomyces avermitilis MA-4680 1213997 NP_823936.1 CDS SAV_2760 NC_003155.4 3387595 3388551 R DeoR family transcriptional regulator complement(3387595..3388551) Streptomyces avermitilis MA-4680 1213998 NP_823937.1 CDS SAV_2761 NC_003155.4 3388666 3389250 D hypothetical protein 3388666..3389250 Streptomyces avermitilis MA-4680 1213999 NP_823938.1 CDS SAV_2762 NC_003155.4 3389237 3390097 R hypothetical protein complement(3389237..3390097) Streptomyces avermitilis MA-4680 1214000 NP_823939.1 CDS SAV_2763 NC_003155.4 3390195 3390851 R PF03458: UPF0126 domain; hypothetical protein complement(3390195..3390851) Streptomyces avermitilis MA-4680 1214001 NP_823940.1 CDS SAV_2764 NC_003155.4 3390899 3392290 R PF01433: Peptidase family M1; metallopeptidase complement(3390899..3392290) Streptomyces avermitilis MA-4680 1214002 NP_823941.1 CDS appF NC_003155.4 3392387 3393913 R tetra,pentapeptide transport system; ABC transporter ATP-binding protein complement(3392387..3393913) Streptomyces avermitilis MA-4680 1210546 NP_823942.1 CDS SAV_2766 NC_003155.4 3393910 3395007 R ABC transporter ATP-binding protein complement(3393910..3395007) Streptomyces avermitilis MA-4680 1214003 NP_823943.1 CDS dppB NC_003155.4 3395004 3396011 R ABC transporter permease complement(3395004..3396011) Streptomyces avermitilis MA-4680 1214004 NP_823944.1 CDS SAV_2768 NC_003155.4 3396081 3397853 R ABC transporter substrate-binding protein complement(3396081..3397853) Streptomyces avermitilis MA-4680 1214005 NP_823945.1 CDS appC NC_003155.4 3397890 3398888 R ABC transporter permease complement(3397890..3398888) Streptomyces avermitilis MA-4680 1214006 NP_823946.1 CDS SAV_2770 NC_003155.4 3399282 3400088 R hypothetical protein complement(3399282..3400088) Streptomyces avermitilis MA-4680 1214007 NP_823947.1 CDS SAV_2771 NC_003155.4 3400233 3401015 R PF07179: SseB protein; hypothetical protein complement(3400233..3401015) Streptomyces avermitilis MA-4680 1214008 NP_823948.1 CDS SAV_2772 NC_003155.4 3401168 3401854 R ATP/GTP-binding protein complement(3401168..3401854) Streptomyces avermitilis MA-4680 1214009 NP_823949.1 CDS gcvT NC_003155.4 3402270 3403388 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system protein T 3402270..3403388 Streptomyces avermitilis MA-4680 1210547 NP_823950.1 CDS gcvH NC_003155.4 3403534 3403911 D part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3403534..3403911 Streptomyces avermitilis MA-4680 1210548 NP_823951.1 CDS glyA NC_003155.4 3403925 3405187 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3403925..3405187 Streptomyces avermitilis MA-4680 1210549 NP_823952.1 CDS sdaA NC_003155.4 3405295 3406662 D L-serine dehydratase 3405295..3406662 Streptomyces avermitilis MA-4680 1210550 NP_823953.1 CDS SAV_2777 NC_003155.4 3406782 3407336 D PF01183: Glycosyl hydrolases family 25; glycosyl hydrolase 3406782..3407336 Streptomyces avermitilis MA-4680 1214010 NP_823954.1 CDS SAV_2778 NC_003155.4 3407533 3407886 D PF03473: MOSC domain; hypothetical protein 3407533..3407886 Streptomyces avermitilis MA-4680 1214011 NP_823955.1 CDS SAV_2779 NC_003155.4 3407939 3408601 R PF03807: NADP oxidoreductase coenzyme F420-dependent; hypothetical protein complement(3407939..3408601) Streptomyces avermitilis MA-4680 1214012 NP_823956.1 CDS SAV_2780 NC_003155.4 3408831 3409043 R PF00036: EF hand; calcium-binding protein complement(3408831..3409043) Streptomyces avermitilis MA-4680 1214013 NP_823957.1 CDS SAV_2781 NC_003155.4 3409094 3410020 R MerR family transcriptional regulator complement(3409094..3410020) Streptomyces avermitilis MA-4680 1214014 NP_823958.1 CDS SAV_2782 NC_003155.4 3410077 3410793 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 3410077..3410793 Streptomyces avermitilis MA-4680 1214015 NP_823959.1 CDS SAV_2783 NC_003155.4 3410760 3411956 R hypothetical protein complement(3410760..3411956) Streptomyces avermitilis MA-4680 1214016 NP_823960.1 CDS SAV_2784 NC_003155.4 3411956 3412846 R polysaccharide deacetylase complement(3411956..3412846) Streptomyces avermitilis MA-4680 1214017 NP_823961.1 CDS SAV_2785 NC_003155.4 3413140 3413748 R regulatory protein complement(3413140..3413748) Streptomyces avermitilis MA-4680 1214018 NP_823962.1 CDS echA8 NC_003155.4 3413998 3414765 R enoyl-CoA hydratase complement(3413998..3414765) Streptomyces avermitilis MA-4680 1210551 NP_823963.1 CDS SAV_2787 NC_003155.4 3414846 3416087 R PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein complement(3414846..3416087) Streptomyces avermitilis MA-4680 1214019 NP_823964.1 CDS SAV_2788 NC_003155.4 3416278 3417507 R PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein complement(3416278..3417507) Streptomyces avermitilis MA-4680 1214020 NP_823965.1 CDS SAV_2789 NC_003155.4 3417664 3419913 D glycogen debranching enzyme 3417664..3419913 Streptomyces avermitilis MA-4680 1214021 NP_823966.1 CDS SAV_2790 NC_003155.4 3419980 3421941 D ABC transporter ATP-binding protein 3419980..3421941 Streptomyces avermitilis MA-4680 1214022 NP_823967.1 CDS SAV_2791 NC_003155.4 3421938 3423800 D ABC transporter ATP-binding protein 3421938..3423800 Streptomyces avermitilis MA-4680 1214023 NP_823968.1 CDS SAV_2792 NC_003155.4 3423822 3425543 D hypothetical protein 3423822..3425543 Streptomyces avermitilis MA-4680 1214024 NP_823969.1 CDS SAV_2793 NC_003155.4 3425540 3427306 D ABC transporter ATP-binding protein 3425540..3427306 Streptomyces avermitilis MA-4680 1214025 NP_823970.1 CDS SAV_2794 NC_003155.4 3427706 3429751 D PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease 3427706..3429751 Streptomyces avermitilis MA-4680 1214026 NP_823971.1 CDS SAV_2795 NC_003155.4 3430049 3431713 D PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease 3430049..3431713 Streptomyces avermitilis MA-4680 1214027 NP_823972.1 CDS SAV_2796 NC_003155.4 3431816 3432322 D hypothetical protein 3431816..3432322 Streptomyces avermitilis MA-4680 1214028 NP_823973.1 CDS SAV_2797 NC_003155.4 3432341 3432931 R regulatory protein complement(3432341..3432931) Streptomyces avermitilis MA-4680 1214029 NP_823974.1 CDS SAV_2798 NC_003155.4 3433035 3433889 D DNA-binding protein 3433035..3433889 Streptomyces avermitilis MA-4680 1214030 NP_823975.1 CDS SAV_2799 NC_003155.4 3433901 3434089 D PF04149: Domain of unknown function (DUF397); hypothetical protein 3433901..3434089 Streptomyces avermitilis MA-4680 1214031 NP_823976.1 CDS glgP NC_003155.4 3434877 3437513 R glycogen phosphorylase complement(3434877..3437513) Streptomyces avermitilis MA-4680 1210552 NP_823977.1 CDS SAV_2801 NC_003155.4 3437980 3439188 D PF00082: Subtilase family; serine protease 3437980..3439188 Streptomyces avermitilis MA-4680 1214032 NP_823978.1 CDS amyA3 NC_003155.4 3439435 3441540 D alpha-amylase 3439435..3441540 Streptomyces avermitilis MA-4680 1210553 NP_823979.1 CDS treS1 NC_003155.4 3441537 3443255 D trehalose synthase 3441537..3443255 Streptomyces avermitilis MA-4680 1214033 NP_823980.1 CDS SAV_2804 NC_003155.4 3443356 3444756 D pep2 protein 3443356..3444756 Streptomyces avermitilis MA-4680 1214034 NP_823981.1 CDS glgB NC_003155.4 3444809 3447325 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 3444809..3447325 Streptomyces avermitilis MA-4680 1210554 NP_823982.1 CDS cyp12 NC_003155.4 3447322 3448770 R CYP182A1; cytochrome P450 complement(3447322..3448770) Streptomyces avermitilis MA-4680 1210555 NP_823983.1 CDS SAV_2807 NC_003155.4 3448795 3451122 R PF00580: UvrD/REP helicase; hypothetical protein complement(3448795..3451122) Streptomyces avermitilis MA-4680 1214035 NP_823984.1 CDS trxA5 NC_003155.4 3451261 3451575 R thioredoxin complement(3451261..3451575) Streptomyces avermitilis MA-4680 1210556 NP_823985.1 CDS SAV_2809 NC_003155.4 3451590 3452018 R MerR family transcriptional regulator complement(3451590..3452018) Streptomyces avermitilis MA-4680 1214036 NP_823986.1 CDS SAV_2810 NC_003155.4 3452062 3452511 R transcription regulator AsnC complement(3452062..3452511) Streptomyces avermitilis MA-4680 1214037 NP_823987.1 CDS SAV_2811 NC_003155.4 3452696 3453592 D reductase 3452696..3453592 Streptomyces avermitilis MA-4680 1214038 NP_823988.1 CDS prcB2 NC_003155.4 3453820 3454674 D PF00227: Proteasome A-type and B-type; 20S proteasome beta-subunit 3453820..3454674 Streptomyces avermitilis MA-4680 1214039 NP_823989.1 CDS SAV_2813 NC_003155.4 3454813 3456540 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(3454813..3456540) Streptomyces avermitilis MA-4680 1214040 NP_823990.1 CDS SAV_2814 NC_003155.4 3456690 3457307 D regulatory protein 3456690..3457307 Streptomyces avermitilis MA-4680 1214041 NP_823991.1 CDS dctA NC_003155.4 3457386 3458798 R PF00375: Sodium:dicarboxylate symporter family; sodium:dicarboxylate symporter complement(3457386..3458798) Streptomyces avermitilis MA-4680 1214042 NP_823992.1 CDS SAV_2816 NC_003155.4 3458968 3460665 D two-component system sensor kinase 3458968..3460665 Streptomyces avermitilis MA-4680 1214043 NP_823993.1 CDS SAV_2817 NC_003155.4 3460662 3461339 D two-component system response regulator 3460662..3461339 Streptomyces avermitilis MA-4680 1214044 NP_823994.1 CDS SAV_2818 NC_003155.4 3461710 3463107 D ABC transporter substrate-binding protein 3461710..3463107 Streptomyces avermitilis MA-4680 1214045 NP_823995.1 CDS SAV_2819 NC_003155.4 3463104 3464033 D ABC transporter permease 3463104..3464033 Streptomyces avermitilis MA-4680 1214046 NP_823996.1 CDS SAV_2820 NC_003155.4 3464035 3464874 D PF00528: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 3464035..3464874 Streptomyces avermitilis MA-4680 1214047 NP_823997.1 CDS SAV_2821 NC_003155.4 3465344 3466060 D hypothetical protein 3465344..3466060 Streptomyces avermitilis MA-4680 1214048 NP_823998.1 CDS pfkA1 NC_003155.4 3466103 3467128 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(3466103..3467128) Streptomyces avermitilis MA-4680 1210557 NP_823999.1 CDS pta NC_003155.4 3467325 3469415 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 3467325..3469415 Streptomyces avermitilis MA-4680 1210558 NP_824000.1 CDS ackA NC_003155.4 3469412 3470629 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3469412..3470629 Streptomyces avermitilis MA-4680 1210559 NP_824001.1 CDS pykA1 NC_003155.4 3470703 3472133 D glycolysis; pyruvate kinase 3470703..3472133 Streptomyces avermitilis MA-4680 1210560 NP_824002.1 CDS SAV_2826 NC_003155.4 3472320 3473618 R PF02987: Late embryogenesis abundant protein; hypothetical protein complement(3472320..3473618) Streptomyces avermitilis MA-4680 1214049 NP_824003.1 CDS SAV_2827 NC_003155.4 3473608 3474174 R hypothetical protein complement(3473608..3474174) Streptomyces avermitilis MA-4680 1214050 NP_824004.1 CDS SAV_2829 NC_003155.4 3474369 3475013 R cholesterol esterase complement(3474369..3475013) Streptomyces avermitilis MA-4680 1214051 NP_824005.1 CDS SAV_2828 NC_003155.4 3474961 3475311 D hypothetical protein 3474961..3475311 Streptomyces avermitilis MA-4680 1214052 NP_824006.1 CDS trxA6 NC_003155.4 3475638 3476624 R thioredoxin complement(3475638..3476624) Streptomyces avermitilis MA-4680 1210561 NP_824007.1 CDS SAV_2831 NC_003155.4 3476861 3477496 D TetR family transcriptional regulator 3476861..3477496 Streptomyces avermitilis MA-4680 1214053 NP_824008.1 CDS icmA NC_003155.4 3477658 3479358 R isobutyryl-CoA mutase subunit A complement(3477658..3479358) Streptomyces avermitilis MA-4680 1210562 NP_824009.1 CDS SAV_2833 NC_003155.4 3479435 3479773 R hypothetical protein complement(3479435..3479773) Streptomyces avermitilis MA-4680 1214054 NP_824010.1 CDS SAV_2834 NC_003155.4 3479839 3480273 R MarR family transcriptional regulator complement(3479839..3480273) Streptomyces avermitilis MA-4680 1214055 NP_824011.1 CDS sppF NC_003155.4 3480598 3482187 R spore-pigment gene cluster, PF01360: Monooxygenase; polyketide hydroxylase complement(3480598..3482187) Streptomyces avermitilis MA-4680 1210563 NP_824012.1 CDS sppG NC_003155.4 3482594 3483718 D spore-pigment gene cluster, PF04486: SchA / CurD like protein; WhiE I-like protein 3482594..3483718 Streptomyces avermitilis MA-4680 1210564 NP_824013.1 CDS sppH NC_003155.4 3483792 3484235 D spore-pigment gene cluster; WhiE II-like protein 3483792..3484235 Streptomyces avermitilis MA-4680 1210565 NP_824014.1 CDS sppA NC_003155.4 3484232 3485497 D spore-pigment gene cluster, PF00109: Beta-ketoacyl synthase, N-terminal domain; 3-oxoacyl-ACP synthase I 3484232..3485497 Streptomyces avermitilis MA-4680 1210566 NP_824015.1 CDS sppB NC_003155.4 3485497 3486747 D spore-pigment gene cluster, PF00109: Beta-ketoacyl synthase, N-terminal domain; 3-oxoacyl-ACP synthase II, chain length factor 3485497..3486747 Streptomyces avermitilis MA-4680 1210567 NP_824016.1 CDS sppC NC_003155.4 3486734 3487018 D spore-pigment gene cluster, PF00550: Phosphopantetheine attachment site; ACP 3486734..3487018 Streptomyces avermitilis MA-4680 1210568 NP_824017.1 CDS sppD NC_003155.4 3487020 3487499 D spore-pigment gene cluster, PF03364: Streptomyces cyclase/dehydrase; cyclase I 3487020..3487499 Streptomyces avermitilis MA-4680 1210569 NP_824018.1 CDS sppE NC_003155.4 3487579 3487905 D spore-pigment gene cluster, PF04673: Polyketide synthesis cyclase; cyclase II 3487579..3487905 Streptomyces avermitilis MA-4680 1210570 NP_824019.1 CDS SAV_2843 NC_003155.4 3488000 3488995 R O-methyltransferase complement(3488000..3488995) Streptomyces avermitilis MA-4680 1214056 NP_824020.1 CDS SAV_2844 NC_003155.4 3489081 3490139 R PF07602: Protein of unknown function (DUF1565); protein complement(3489081..3490139) Streptomyces avermitilis MA-4680 1214057 NP_824021.1 CDS SAV_2845 NC_003155.4 3490385 3491017 R TetR family transcriptional regulator complement(3490385..3491017) Streptomyces avermitilis MA-4680 1214058 NP_824022.1 CDS SAV_2846 NC_003155.4 3491014 3491694 R hypothetical protein complement(3491014..3491694) Streptomyces avermitilis MA-4680 1214059 NP_824023.1 CDS SAV_2847 NC_003155.4 3491691 3492443 R hypothetical protein complement(3491691..3492443) Streptomyces avermitilis MA-4680 1214060 NP_824024.1 CDS SAV_2848 NC_003155.4 3492609 3492902 R PF01910: Domain of unknown function DUF77; hypothetical protein complement(3492609..3492902) Streptomyces avermitilis MA-4680 1214061 NP_824025.1 CDS SAV_2849 NC_003155.4 3492899 3493243 R hypothetical protein complement(3492899..3493243) Streptomyces avermitilis MA-4680 1214062 NP_824026.1 CDS SAV_2850 NC_003155.4 3493420 3494052 D PF01987: Protein of unknown function DUF124; hypothetical protein 3493420..3494052 Streptomyces avermitilis MA-4680 1214063 NP_824027.1 CDS SAV_2851 NC_003155.4 3494045 3494704 D PF01987: Protein of unknown function DUF124; hypothetical protein 3494045..3494704 Streptomyces avermitilis MA-4680 1214064 NP_824028.1 CDS SAV_2852 NC_003155.4 3494701 3495498 D PF01987: Protein of unknown function DUF124; hypothetical protein 3494701..3495498 Streptomyces avermitilis MA-4680 1214065 NP_824029.1 CDS SAV_2853 NC_003155.4 3495591 3496067 D MarR family transcriptional regulator 3495591..3496067 Streptomyces avermitilis MA-4680 1214066 NP_824030.1 CDS SAV_2854 NC_003155.4 3496431 3497429 R PF07690: Major Facilitator Superfamily; hypothetical protein complement(3496431..3497429) Streptomyces avermitilis MA-4680 1214067 NP_824031.1 CDS argK2 NC_003155.4 3497612 3498568 R lysine arginine ornithine transport system kinase complement(3497612..3498568) Streptomyces avermitilis MA-4680 1214068 NP_824032.1 CDS fadA1 NC_003155.4 3498639 3499841 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3498639..3499841) Streptomyces avermitilis MA-4680 1210571 NP_824033.1 CDS SAV_2857 NC_003155.4 3499939 3500430 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 3499939..3500430 Streptomyces avermitilis MA-4680 1214069 NP_824034.1 CDS SAV_2858 NC_003155.4 3500758 3504534 D PF02370: M protein repeat; M protein 3500758..3504534 Streptomyces avermitilis MA-4680 1214070 NP_824035.1 CDS SAV_2859 NC_003155.4 3504717 3505655 D cellulose-binding protein 3504717..3505655 Streptomyces avermitilis MA-4680 1214071 NP_824036.1 CDS SAV_2860 NC_003155.4 3505744 3506694 D ABC transporter ATP-binding protein 3505744..3506694 Streptomyces avermitilis MA-4680 1214072 NP_824037.1 CDS SAV_2861 NC_003155.4 3506697 3507467 D ABC transporter permease 3506697..3507467 Streptomyces avermitilis MA-4680 1214073 NP_824038.1 CDS SAV_2862 NC_003155.4 3507648 3508979 D ABC transporter ATP-binding protein 3507648..3508979 Streptomyces avermitilis MA-4680 1214074 NP_824039.1 CDS SAV_2863 NC_003155.4 3509005 3509874 D ABC transporter permease 3509005..3509874 Streptomyces avermitilis MA-4680 1214075 NP_824040.1 CDS SAV_2864 NC_003155.4 3509904 3510236 R ATP/GTP-binding protein complement(3509904..3510236) Streptomyces avermitilis MA-4680 1214076 NP_824041.1 CDS SAV_2865 NC_003155.4 3510457 3511485 D luciferase-family protein 3510457..3511485 Streptomyces avermitilis MA-4680 1214077 NP_824042.1 CDS SAV_2866 NC_003155.4 3511582 3511974 R hypothetical protein complement(3511582..3511974) Streptomyces avermitilis MA-4680 1214078 NP_824043.1 CDS SAV_2867 NC_003155.4 3512218 3512889 D PF01939: Protein of unknown function DUF91; hypothetical protein 3512218..3512889 Streptomyces avermitilis MA-4680 1214079 NP_824044.1 CDS SAV_2868 NC_003155.4 3513017 3515560 R PF05729: NACHT domain; hypothetical protein complement(3513017..3515560) Streptomyces avermitilis MA-4680 1214080 NP_824045.1 CDS SAV_2869 NC_003155.4 3515964 3516287 R PF01740: STAS domain; anti-sigma factor antagonist complement(3515964..3516287) Streptomyces avermitilis MA-4680 1214081 NP_824046.1 CDS fadC3 NC_003155.4 3516433 3517281 R PF02737: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase complement(3516433..3517281) Streptomyces avermitilis MA-4680 1210572 NP_824047.1 CDS SAV_2871 NC_003155.4 3517449 3518090 R TetR family transcriptional regulator complement(3517449..3518090) Streptomyces avermitilis MA-4680 1214082 NP_824048.1 CDS SAV_2872 NC_003155.4 3518171 3518953 D ABC transporter ATP-binding protein 3518171..3518953 Streptomyces avermitilis MA-4680 1214083 NP_824049.1 CDS SAV_2873 NC_003155.4 3518985 3519734 D hypothetical protein 3518985..3519734 Streptomyces avermitilis MA-4680 1214084 NP_824050.1 CDS SAV_2874 NC_003155.4 3519748 3520320 D cobalamin adenosyltransferase 3519748..3520320 Streptomyces avermitilis MA-4680 1214085 NP_824051.1 CDS SAV_2875 NC_003155.4 3520317 3520940 R hypothetical protein complement(3520317..3520940) Streptomyces avermitilis MA-4680 1214086 NP_824052.1 CDS chiS NC_003155.4 3521015 3522199 D two-component system sensor kinase 3521015..3522199 Streptomyces avermitilis MA-4680 1210573 NP_824053.1 CDS chiR NC_003155.4 3522196 3522837 D two-component system response regulator 3522196..3522837 Streptomyces avermitilis MA-4680 1210574 NP_824054.1 CDS chiC NC_003155.4 3522979 3524802 D chitinase C precursor 3522979..3524802 Streptomyces avermitilis MA-4680 1210575 NP_824055.1 CDS SAV_2879 NC_003155.4 3524875 3525327 R hypothetical protein complement(3524875..3525327) Streptomyces avermitilis MA-4680 1214087 NP_824056.1 CDS atpC NC_003155.4 3525460 3525834 R produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon complement(3525460..3525834) Streptomyces avermitilis MA-4680 1210576 NP_824057.1 CDS atpD NC_003155.4 3525945 3527381 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(3525945..3527381) Streptomyces avermitilis MA-4680 1210577 NP_824058.1 CDS atpG NC_003155.4 3527381 3528298 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(3527381..3528298) Streptomyces avermitilis MA-4680 1210578 NP_824059.1 CDS atpA NC_003155.4 3528320 3529909 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(3528320..3529909) Streptomyces avermitilis MA-4680 1210579 NP_824060.1 CDS atpH NC_003155.4 3530039 3530860 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(3530039..3530860) Streptomyces avermitilis MA-4680 1210580 NP_824061.1 CDS atpF NC_003155.4 3530857 3531417 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(3530857..3531417) Streptomyces avermitilis MA-4680 1210581 NP_824062.1 CDS atpE NC_003155.4 3531439 3531681 R PF00137: ATP synthase subunit C; F-type proton-transporting ATPase c chain complement(3531439..3531681) Streptomyces avermitilis MA-4680 1210582 NP_824063.1 CDS atpB NC_003155.4 3531750 3532559 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(3531750..3532559) Streptomyces avermitilis MA-4680 1210583 NP_824064.1 CDS atpI NC_003155.4 3532782 3533195 R PF06942: GlpM protein; ATP synthase protein I complement(3532782..3533195) Streptomyces avermitilis MA-4680 1210584 NP_824065.1 CDS fadC4 NC_003155.4 3533486 3534304 R converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase complement(3533486..3534304) Streptomyces avermitilis MA-4680 1210585 NP_824066.1 CDS ccrA1 NC_003155.4 3534525 3535877 R concerning oligomycin biosynthesis; crotonyl-CoA reductase complement(3534525..3535877) Streptomyces avermitilis MA-4680 1210586 NP_824067.1 CDS SAV_2891 NC_003155.4 3536018 3536521 R hypothetical protein complement(3536018..3536521) Streptomyces avermitilis MA-4680 1214088 NP_824068.1 CDS olmA4 NC_003155.4 3536766 3548678 D oligomycin gene cluster; modular polyketide synthase 3536766..3548678 Streptomyces avermitilis MA-4680 1210587 NP_824069.1 CDS olmA5 NC_003155.4 3548827 3554550 D oligomycin gene cluster; modular polyketide synthase 3548827..3554550 Streptomyces avermitilis MA-4680 1210588 NP_824070.1 CDS olmB NC_003155.4 3554746 3555960 D CYP107W1, oligomycin gene cluster; cytochrome P450 hydroxylase 3554746..3555960 Streptomyces avermitilis MA-4680 1210589 NP_824071.1 CDS olmA7 NC_003155.4 3556431 3567272 R oligomycin gene cluster; modular polyketide synthase complement(3556431..3567272) Streptomyces avermitilis MA-4680 1210590 NP_824072.1 CDS olmA6 NC_003155.4 3567331 3581388 R oligomycin gene cluster; modular polyketide synthase complement(3567331..3581388) Streptomyces avermitilis MA-4680 1210591 NP_824073.1 CDS olmA3 NC_003155.4 3581534 3593353 R oligomycin gene cluster; modular polyketide synthase complement(3581534..3593353) Streptomyces avermitilis MA-4680 1210592 NP_824074.1 CDS olmA2 NC_003155.4 3593359 3607881 R oligomycin gene cluster; modular polyketide synthase complement(3593359..3607881) Streptomyces avermitilis MA-4680 1210593 NP_824075.1 CDS olmA1 NC_003155.4 3607907 3626347 R oligomycin gene cluster; modular polyketide synthase complement(3607907..3626347) Streptomyces avermitilis MA-4680 1210594 NP_824076.1 CDS SAV_2900 NC_003155.4 3626534 3626872 R probably pseudogene; P450-like protein complement(3626534..3626872) Streptomyces avermitilis MA-4680 1214089 NP_824077.1 CDS olmRII NC_003155.4 3627319 3630147 R oligomycin gene cluster; LuxR family transcriptional regulator complement(3627319..3630147) Streptomyces avermitilis MA-4680 1210595 NP_824078.1 CDS olmRI NC_003155.4 3630367 3633162 R oligomycin gene cluster; LuxR family transcriptional regulator complement(3630367..3633162) Streptomyces avermitilis MA-4680 1210596 NP_824079.1 CDS olmC NC_003155.4 3633834 3634592 R oligomycin gene cluster; thioesterase complement(3633834..3634592) Streptomyces avermitilis MA-4680 1210597 NP_824080.1 CDS SAV_2904 NC_003155.4 3634930 3635895 D SimX4-like protein 3634930..3635895 Streptomyces avermitilis MA-4680 1214090 NP_824081.1 CDS pptA1 NC_003155.4 3635892 3636674 D PF01648: 4'-phosphopantetheinyl transferase superfamily; phosphopantetheinyl transferase 3635892..3636674 Streptomyces avermitilis MA-4680 1210598 NP_824082.1 CDS mcmA1 NC_003155.4 3636671 3637804 D methylmalonyl-CoA mutase subunit alpha 3636671..3637804 Streptomyces avermitilis MA-4680 1210599 NP_824083.1 CDS tagO NC_003155.4 3637912 3639336 R teichoic acid linkage unit synthesis (synthesis of UDPpyrophosphate-N- aetylglucosamine) complement(3637912..3639336) Streptomyces avermitilis MA-4680 1210600 NP_824084.1 CDS glyA2 NC_003155.4 3639464 3640735 R serine hydroxymethyltransferase complement(3639464..3640735) Streptomyces avermitilis MA-4680 1210601 NP_824085.1 CDS ptpB3 NC_003155.4 3640880 3641545 R PF01451: Low molecular weight phosphotyrosine protein phosphatase; low molecular weight protein tyrosine phosphatase complement(3640880..3641545) Streptomyces avermitilis MA-4680 1214091 NP_824086.1 CDS SAV_2910 NC_003155.4 3641542 3642189 R PF01300: yrdC domain; hypothetical protein complement(3641542..3642189) Streptomyces avermitilis MA-4680 1214092 NP_824087.1 CDS SAV_2911 NC_003155.4 3642242 3643123 R methyltransferase complement(3642242..3643123) Streptomyces avermitilis MA-4680 1214093 NP_824088.1 CDS prfA NC_003155.4 3643170 3644246 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(3643170..3644246) Streptomyces avermitilis MA-4680 1210602 NP_824089.1 CDS rpmE NC_003155.4 3644421 3644642 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(3644421..3644642) Streptomyces avermitilis MA-4680 1210603 NP_824090.1 CDS SAV_2914 NC_003155.4 3644839 3645978 R transcriptional regulator complement(3644839..3645978) Streptomyces avermitilis MA-4680 1214094 NP_824091.1 CDS rho NC_003155.4 3646335 3648401 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(3646335..3648401) Streptomyces avermitilis MA-4680 1210604 NP_824092.1 CDS thrB NC_003155.4 3648821 3649738 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(3648821..3649738) Streptomyces avermitilis MA-4680 1210605 NP_824093.1 CDS thrC1 NC_003155.4 3650076 3651134 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(3650076..3651134) Streptomyces avermitilis MA-4680 1210606 NP_824094.1 CDS thrA NC_003155.4 3651141 3652430 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(3651141..3652430) Streptomyces avermitilis MA-4680 1210607 NP_824095.1 CDS lysA1 NC_003155.4 3652587 3653978 R PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain; diaminopimelate decarboxylase complement(3652587..3653978) Streptomyces avermitilis MA-4680 1210608 NP_824096.1 CDS argS1 NC_003155.4 3654002 3655060 R arginyl-tRNA synthetase complement(3654002..3655060) Streptomyces avermitilis MA-4680 1210609 NP_824097.1 CDS SAV_2921 NC_003155.4 3655220 3655813 R two-component system response regulator complement(3655220..3655813) Streptomyces avermitilis MA-4680 1214095 NP_824098.1 CDS SAV_2922 NC_003155.4 3656330 3657742 R integrin homolog, PF01839: FG-GAP repeat; hypothetical protein complement(3656330..3657742) Streptomyces avermitilis MA-4680 1214096 NP_824099.1 CDS SAV_2923 NC_003155.4 3657810 3659339 R integrin homolog, PF01839: FG-GAP repeat; hypothetical protein complement(3657810..3659339) Streptomyces avermitilis MA-4680 1214097 NP_824100.1 CDS SAV_2924 NC_003155.4 3659419 3659685 D hypothetical protein 3659419..3659685 Streptomyces avermitilis MA-4680 1214098 NP_824101.1 CDS SAV_2925 NC_003155.4 3662215 3664023 R hypothetical protein complement(3662215..3664023) Streptomyces avermitilis MA-4680 1214099 NP_824102.1 CDS SAV_2926 NC_003155.4 3664680 3666734 R PF02463: RecF/RecN/SMC N terminal domain; hypothetical protein complement(3664680..3666734) Streptomyces avermitilis MA-4680 1214100 NP_824103.1 CDS SAV_2927 NC_003155.4 3666731 3666895 R hypothetical protein complement(3666731..3666895) Streptomyces avermitilis MA-4680 1214101 NP_824104.1 CDS SAV_2928 NC_003155.4 3666923 3669067 R DNA repair helicase complement(3666923..3669067) Streptomyces avermitilis MA-4680 1214102 NP_824105.1 CDS SAV_2929 NC_003155.4 3672466 3672861 R hypothetical protein complement(3672466..3672861) Streptomyces avermitilis MA-4680 1214103 NP_824106.1 CDS SAV_2930 NC_003155.4 3672836 3674863 R PF02463: RecF/RecN/SMC N terminal domain; hypothetical protein complement(3672836..3674863) Streptomyces avermitilis MA-4680 1214104 NP_824107.1 CDS SAV_2931 NC_003155.4 3674850 3676427 R PF01507: Phosphoadenosine phosphosulfate reductase family; hypothetical protein complement(3674850..3676427) Streptomyces avermitilis MA-4680 1214105 NP_824108.1 CDS SAV_2932 NC_003155.4 3676424 3677563 R hypothetical protein complement(3676424..3677563) Streptomyces avermitilis MA-4680 1214106 NP_824109.1 CDS iscS NC_003155.4 3677808 3678962 D L-cysteine desulfurase (pyridoxal phosphate-dependent) 3677808..3678962 Streptomyces avermitilis MA-4680 1210611 NP_824110.1 CDS SAV_2934 NC_003155.4 3678968 3680404 R hypothetical protein complement(3678968..3680404) Streptomyces avermitilis MA-4680 1214107 NP_824111.1 CDS SAV_2935 NC_003155.4 3683155 3683652 D hypothetical protein 3683155..3683652 Streptomyces avermitilis MA-4680 1214108 NP_824112.1 CDS int5 NC_003155.4 3683691 3684662 R PF00589: Phage integrase family; integrase complement(3683691..3684662) Streptomyces avermitilis MA-4680 1214109 NP_824113.1 CDS int6 NC_003155.4 3684643 3684981 R integrase complement(3684643..3684981) Streptomyces avermitilis MA-4680 1214110 NP_824114.1 CDS repSA3 NC_003155.4 3685159 3685857 R replication initiator protein complement(3685159..3685857) Streptomyces avermitilis MA-4680 1210612 NP_824115.1 CDS SAV_2939 NC_003155.4 3686010 3686846 R PF02031: Streptomyces extracellular neutral proteinase (M7) family; metalloprotease complement(3686010..3686846) Streptomyces avermitilis MA-4680 1214111 NP_824116.1 CDS SAV_2940 NC_003155.4 3687593 3688159 R hypothetical protein complement(3687593..3688159) Streptomyces avermitilis MA-4680 1214112 NP_824117.1 CDS SAV_2941 NC_003155.4 3689026 3689523 D hypothetical protein 3689026..3689523 Streptomyces avermitilis MA-4680 1214113 NP_824118.1 CDS SAV_2942 NC_003155.4 3689583 3689798 D hypothetical protein 3689583..3689798 Streptomyces avermitilis MA-4680 1214114 NP_824119.1 CDS SAV_2943 NC_003155.4 3689937 3691580 R hypothetical protein complement(3689937..3691580) Streptomyces avermitilis MA-4680 1214115 NP_824120.1 CDS fabB2 NC_003155.4 3692368 3693618 D PF00109: Beta-ketoacyl synthase, N-terminal domain; 3-oxoacyl-ACP synthase II 3692368..3693618 Streptomyces avermitilis MA-4680 1210613 NP_824121.1 CDS ku1 NC_003155.4 3693749 3694849 R probably involving non-homologous end-joining; Ku70/Ku80 protein complement(3693749..3694849) Streptomyces avermitilis MA-4680 1214116 NP_824122.1 CDS ligD NC_003155.4 3694892 3695773 D ATP-dependent DNA ligase; DNA ligase 3694892..3695773 Streptomyces avermitilis MA-4680 1214117 NP_824123.1 CDS SAV_2947 NC_003155.4 3695855 3696658 R hypothetical protein complement(3695855..3696658) Streptomyces avermitilis MA-4680 1214118 NP_824124.1 CDS ptpA3 NC_003155.4 3696783 3697262 D PF00782: Dual specificity phosphatase, catalytic domain; conventional protein tyrosine phosphatase 3696783..3697262 Streptomyces avermitilis MA-4680 1214119 NP_824125.1 CDS SAV_2949 NC_003155.4 3697443 3698333 D lipoprotein 3697443..3698333 Streptomyces avermitilis MA-4680 1214120 NP_824126.1 CDS SAV_2950 NC_003155.4 3698330 3699625 D two-component system sensor kinase 3698330..3699625 Streptomyces avermitilis MA-4680 1214121 NP_824127.1 CDS ftsW4 NC_003155.4 3699662 3701029 D PF01098: Cell cycle protein; cell division membrane protein 3699662..3701029 Streptomyces avermitilis MA-4680 1214122 NP_824128.1 CDS pbp1 NC_003155.4 3701049 3702506 D PF00905: Penicillin binding protein transpeptidase domain; penicillin-binding protein 3701049..3702506 Streptomyces avermitilis MA-4680 1210614 NP_824129.1 CDS SAV_2953 NC_003155.4 3702582 3703688 R hypothetical protein complement(3702582..3703688) Streptomyces avermitilis MA-4680 1214123 NP_824130.1 CDS SAV_2954 NC_003155.4 3703839 3704774 D hypothetical protein 3703839..3704774 Streptomyces avermitilis MA-4680 1214124 NP_824131.1 CDS SAV_2955 NC_003155.4 3705104 3705829 D TetR family transcriptional regulator 3705104..3705829 Streptomyces avermitilis MA-4680 1214125 NP_824132.1 CDS SAV_2956 NC_003155.4 3705840 3706205 D hypothetical protein 3705840..3706205 Streptomyces avermitilis MA-4680 1214126 NP_824133.1 CDS SAV_2957 NC_003155.4 3706309 3707724 D NLP/P60-family protein 3706309..3707724 Streptomyces avermitilis MA-4680 1214127 NP_824134.1 CDS SAV_2958 NC_003155.4 3707729 3708982 R oxygenase subunit complement(3707729..3708982) Streptomyces avermitilis MA-4680 1214128 NP_824135.1 CDS cvnD8 NC_003155.4 3709010 3709636 R multi-component regulatory system-8; ATP/GTP-binding protein complement(3709010..3709636) Streptomyces avermitilis MA-4680 1210615 NP_824136.1 CDS cvnC8 NC_003155.4 3709617 3710033 R multi-component regulatory system-8, PF05331: Protein of unknown function (DUF742); hypothetical protein complement(3709617..3710033) Streptomyces avermitilis MA-4680 1210616 NP_824137.1 CDS cvnB8 NC_003155.4 3710030 3710455 R multi-component regulatory system-8, PF03259: Roadblock/LC7 domain; hypothetical protein complement(3710030..3710455) Streptomyces avermitilis MA-4680 1210617 NP_824138.1 CDS cvnA8 NC_003155.4 3710530 3713454 R multi-component regulatory system-8; sensor-like histidine kinase complement(3710530..3713454) Streptomyces avermitilis MA-4680 1210618 NP_824139.1 CDS SAV_2963 NC_003155.4 3713815 3714603 D hypothetical protein 3713815..3714603 Streptomyces avermitilis MA-4680 1214129 NP_824140.1 CDS SAV_2964 NC_003155.4 3714919 3715434 R MarR family transcriptional regulator complement(3714919..3715434) Streptomyces avermitilis MA-4680 1214130 NP_824141.1 CDS SAV_2965 NC_003155.4 3715703 3716521 D PF01183: Glycosyl hydrolases family 25; lysozyme precursor 3715703..3716521 Streptomyces avermitilis MA-4680 1214131 NP_824142.1 CDS lonA NC_003155.4 3716613 3719048 R PF05362: Lon protease (S16) C-terminal proteolytic domain; lon class III heat-shock ATP-dependent protease complement(3716613..3719048) Streptomyces avermitilis MA-4680 1210619 NP_824143.1 CDS SAV_2967 NC_003155.4 3719100 3719969 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 3719100..3719969 Streptomyces avermitilis MA-4680 1214132 NP_824144.1 CDS SAV_2968 NC_003155.4 3720061 3721011 R hypothetical protein complement(3720061..3721011) Streptomyces avermitilis MA-4680 1214133 NP_824145.1 CDS SAV_2969 NC_003155.4 3721098 3721775 D hypothetical protein 3721098..3721775 Streptomyces avermitilis MA-4680 1214134 NP_824146.1 CDS SAV_2970 NC_003155.4 3721889 3722626 D two-component system response regulator 3721889..3722626 Streptomyces avermitilis MA-4680 1214135 NP_824147.1 CDS SAV_2971 NC_003155.4 3722623 3723729 D two-component system sensor kinase 3722623..3723729 Streptomyces avermitilis MA-4680 1214136 NP_824148.1 CDS kgd NC_003155.4 3724011 3727841 D kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 3724011..3727841 Streptomyces avermitilis MA-4680 1210620 NP_824149.1 CDS SAV_2973 NC_003155.4 3727917 3731909 R ATP/GTP-binding protein complement(3727917..3731909) Streptomyces avermitilis MA-4680 1214137 NP_824150.1 CDS SAV_2974 NC_003155.4 3732001 3732165 D hypothetical protein 3732001..3732165 Streptomyces avermitilis MA-4680 1214138 NP_824151.1 CDS SAV_2975 NC_003155.4 3732202 3732525 D hypothetical protein 3732202..3732525 Streptomyces avermitilis MA-4680 1214139 NP_824152.1 CDS SAV_2976 NC_003155.4 3732823 3733992 D hypothetical protein 3732823..3733992 Streptomyces avermitilis MA-4680 1214140 NP_824153.1 CDS SAV_2977 NC_003155.4 3733994 3735070 D PadR-like family transcriptional regulator 3733994..3735070 Streptomyces avermitilis MA-4680 1214141 NP_824154.1 CDS SAV_2978 NC_003155.4 3735319 3735885 R PF02861: Clp amino terminal domain; hypothetical protein complement(3735319..3735885) Streptomyces avermitilis MA-4680 1214142 NP_824155.1 CDS SAV_2979 NC_003155.4 3735885 3736094 R hypothetical protein complement(3735885..3736094) Streptomyces avermitilis MA-4680 1214143 NP_824156.1 CDS SAV_2980 NC_003155.4 3736264 3737229 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(3736264..3737229) Streptomyces avermitilis MA-4680 1214144 NP_824157.1 CDS SAV_2981 NC_003155.4 3737501 3738724 R PF03949: Malic enzyme, NAD binding domain; malate oxidoreductase complement(3737501..3738724) Streptomyces avermitilis MA-4680 1214145 NP_824158.1 CDS aotJ NC_003155.4 3739316 3740275 D ABC transporter periplasmic component; arginine/ornithine binding protein 3739316..3740275 Streptomyces avermitilis MA-4680 1210621 NP_824159.1 CDS aotM NC_003155.4 3740309 3741247 D ABC transporter permease; arginine/ornithine transport permease 3740309..3741247 Streptomyces avermitilis MA-4680 1210622 NP_824160.1 CDS aotP NC_003155.4 3741244 3742035 D ABC transporter ATP-binding protein; arginine/ornithine transport ATP-binding protein 3741244..3742035 Streptomyces avermitilis MA-4680 1210623 NP_824161.1 CDS metZ NC_003155.4 3742164 3742949 R methyltransferase complement(3742164..3742949) Streptomyces avermitilis MA-4680 1210624 NP_824162.1 CDS SAV_2986 NC_003155.4 3743033 3743662 D PF07336: Protein of unknown function (DUF1470); hypothetical protein 3743033..3743662 Streptomyces avermitilis MA-4680 1214146 NP_824163.1 CDS SAV_2987 NC_003155.4 3743566 3744000 R PF00717: Peptidase S24-like; signal peptidase protein complement(3743566..3744000) Streptomyces avermitilis MA-4680 1214147 NP_824164.1 CDS sodN NC_003155.4 3744146 3744541 D Ni-containing superoxide dismutase; superoxide dismutase 3744146..3744541 Streptomyces avermitilis MA-4680 1210625 NP_824165.1 CDS SAV_2989 NC_003155.4 3744875 3745384 R MarR family transcriptional regulator complement(3744875..3745384) Streptomyces avermitilis MA-4680 1214148 NP_824166.1 CDS gap1 NC_003155.4 3745497 3746501 D ptlK, probably pentalenolactone resistance gene; glyceraldehyde-3-phosphate dehydrogenase 3745497..3746501 Streptomyces avermitilis MA-4680 1210626 NP_824167.1 CDS ptlH NC_003155.4 3746784 3747719 D pentalenolactone gene cluster, PF05721: Phytanoyl-CoA dioxygenase (PhyH); hypothetical protein 3746784..3747719 Streptomyces avermitilis MA-4680 1210627 NP_824168.1 CDS ptlG NC_003155.4 3747777 3749231 D pentalenolactone gene cluster, PF07690: Major Facilitator Superfamily; transport protein 3747777..3749231 Streptomyces avermitilis MA-4680 1210628 NP_824169.1 CDS ptlF NC_003155.4 3749307 3750119 D pentalenolactone gene cluster, PF00106: short chain dehydrogenase; oxidoreductase 3749307..3750119 Streptomyces avermitilis MA-4680 1210629 NP_824170.1 CDS ptlE NC_003155.4 3750177 3751961 D pentalenolactone gene cluster, PF00743: Flavin-binding monooxygenase-like; monooxygenase 3750177..3751961 Streptomyces avermitilis MA-4680 1210630 NP_824171.1 CDS ptlD NC_003155.4 3751962 3752882 D pentalenolactone gene cluster, PF02668: Taurine catabolism dioxygenase TauD, TfdA family; dioxygenase 3751962..3752882 Streptomyces avermitilis MA-4680 1210631 NP_824172.1 CDS ptlC NC_003155.4 3752934 3753110 D pentalenolactone gene cluster; hypothetical protein 3752934..3753110 Streptomyces avermitilis MA-4680 1210632 NP_824173.1 CDS ptlB NC_003155.4 3753107 3754120 D pentalenolactone gene cluster, probably farnesyl pyrophosphate synthase (idsA2); polyprenyl diphosphate synthase 3753107..3754120 Streptomyces avermitilis MA-4680 1210633 NP_824174.1 CDS ptlA NC_003155.4 3754725 3755735 D pentalenolactone gene cluster; pentalenene synthase 3754725..3755735 Streptomyces avermitilis MA-4680 1210634 NP_824175.1 CDS ptlI NC_003155.4 3755792 3757141 D cyp13, CYP183A1, pentalenolactone gene cluster; cytochrome P450 3755792..3757141 Streptomyces avermitilis MA-4680 1210635 NP_824176.1 CDS ptlR NC_003155.4 3757201 3757662 D pentalenolactone gene cluster; AraC family transcription regulator 3757201..3757662 Streptomyces avermitilis MA-4680 1210636 NP_824177.1 CDS ptlJ NC_003155.4 3757659 3758093 D pentalenolactone gene cluster; lyase 3757659..3758093 Streptomyces avermitilis MA-4680 1210637 NP_824178.1 CDS SAV_3002 NC_003155.4 3758163 3758933 D hypothetical protein 3758163..3758933 Streptomyces avermitilis MA-4680 1214149 NP_824179.1 CDS SAV_3003 NC_003155.4 3759224 3759571 R PF06108: Protein of unknown function (DUF952); hypothetical protein complement(3759224..3759571) Streptomyces avermitilis MA-4680 1214150 NP_824180.1 CDS SAV_3004 NC_003155.4 3759667 3759882 R hypothetical protein complement(3759667..3759882) Streptomyces avermitilis MA-4680 1214151 NP_824181.1 CDS SAV_3005 NC_003155.4 3759930 3760520 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(3759930..3760520) Streptomyces avermitilis MA-4680 1214152 NP_824182.1 CDS idsB NC_003155.4 3760742 3761926 R probably farnesyl pyrophosphate synthase; polyprenyl diphosphate synthase complement(3760742..3761926) Streptomyces avermitilis MA-4680 1210638 NP_824183.1 CDS eshA NC_003155.4 3762063 3763469 R similar to sporulation-specific protein; nucleotide-binding protein complement(3762063..3763469) Streptomyces avermitilis MA-4680 1210639 NP_824184.1 CDS SAV_3008 NC_003155.4 3764080 3764757 D PF01510: N-acetylmuramoyl-L-alanine amidase; hypothetical protein 3764080..3764757 Streptomyces avermitilis MA-4680 1214153 NP_824185.1 CDS SAV_3009 NC_003155.4 3764786 3765721 D 1-aminocyclopropane-1-carboxylate deaminase 3764786..3765721 Streptomyces avermitilis MA-4680 1214154 NP_824186.1 CDS SAV_3010 NC_003155.4 3765728 3767329 R PF00999: Sodium/hydrogen exchanger family; sodium/proton antiporter complement(3765728..3767329) Streptomyces avermitilis MA-4680 1214155 NP_824187.1 CDS SAV_3011 NC_003155.4 3767391 3767651 D PF02148: Zn-finger in ubiquitin-hydrolases and other protein; hypothetical protein 3767391..3767651 Streptomyces avermitilis MA-4680 1214156 NP_824188.1 CDS rsbW NC_003155.4 3767924 3768337 D rshA; anti-sigma factor 3767924..3768337 Streptomyces avermitilis MA-4680 1210640 NP_824189.1 CDS sig21 NC_003155.4 3768334 3769509 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor, sigH 3768334..3769509 Streptomyces avermitilis MA-4680 1210641 NP_824190.1 CDS SAV_3014 NC_003155.4 3769563 3770036 R integral membrane protein complement(3769563..3770036) Streptomyces avermitilis MA-4680 1214157 NP_824191.1 CDS SAV_3015 NC_003155.4 3770150 3771118 D PF00781: Diacylglycerol kinase catalytic domain (presumed); hypothetical protein 3770150..3771118 Streptomyces avermitilis MA-4680 1214158 NP_824192.1 CDS wblE NC_003155.4 3771438 3771695 D PF02467: Transcription factor WhiB; WhiB-family transcriptional regulator 3771438..3771695 Streptomyces avermitilis MA-4680 1210642 NP_824193.1 CDS SAV_3017 NC_003155.4 3771944 3773449 R two-component system sensor kinase complement(3771944..3773449) Streptomyces avermitilis MA-4680 1214159 NP_824194.1 CDS nagB NC_003155.4 3773972 3774757 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 3773972..3774757 Streptomyces avermitilis MA-4680 1210643 NP_824195.1 CDS nagZ1 NC_003155.4 3774850 3776454 R beta-N-acetylhexosaminidase complement(3774850..3776454) Streptomyces avermitilis MA-4680 1214160 NP_824196.1 CDS SAV_3020 NC_003155.4 3776463 3777305 R sugar ABC transporter permease complement(3776463..3777305) Streptomyces avermitilis MA-4680 1214161 NP_824197.1 CDS SAV_3021 NC_003155.4 3777302 3778291 R sugar ABC transporter permease complement(3777302..3778291) Streptomyces avermitilis MA-4680 1214162 NP_824198.1 CDS SAV_3022 NC_003155.4 3778407 3779726 R sugar ABC transporter substrate-binding protein complement(3778407..3779726) Streptomyces avermitilis MA-4680 1214163 NP_824199.1 CDS SAV_3023 NC_003155.4 3780104 3780868 D PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator 3780104..3780868 Streptomyces avermitilis MA-4680 1214164 NP_824200.1 CDS SAV_3024 NC_003155.4 3781105 3781359 D hypothetical protein 3781105..3781359 Streptomyces avermitilis MA-4680 1214165 NP_824201.1 CDS SAV_3025 NC_003155.4 3781368 3782984 D PF00474: Sodium:solute symporter family; sodium/proline symporter 3781368..3782984 Streptomyces avermitilis MA-4680 1214166 NP_824202.1 CDS nrdL NC_003155.4 3783420 3785801 D ribonucleoside-diphosphate reductase alpha chain 3783420..3785801 Streptomyces avermitilis MA-4680 1210644 NP_824203.1 CDS nrdM NC_003155.4 3785798 3786814 D ribonucleoside-diphosphate reductase beta chain 3785798..3786814 Streptomyces avermitilis MA-4680 1210645 NP_824204.1 CDS SAV_3028 NC_003155.4 3786909 3787418 D hypothetical protein 3786909..3787418 Streptomyces avermitilis MA-4680 1214167 NP_824205.1 CDS SAV_3029 NC_003155.4 3787379 3787609 R hypothetical protein complement(3787379..3787609) Streptomyces avermitilis MA-4680 1214168 NP_824206.1 CDS SAV_3030 NC_003155.4 3787680 3788660 D AraC family transcription regulator 3787680..3788660 Streptomyces avermitilis MA-4680 1214169 NP_824207.1 CDS cyp14 NC_003155.4 3788761 3790131 R CYP170A2; cytochrome P450 hydroxylase complement(3788761..3790131) Streptomyces avermitilis MA-4680 1210646 NP_824208.1 CDS tpc2 NC_003155.4 3790128 3791219 R terpene biosynthesis; terpene cyclase complement(3790128..3791219) Streptomyces avermitilis MA-4680 1210647 NP_824209.1 CDS def1 NC_003155.4 3791551 3792201 R polypeptide deformylase complement(3791551..3792201) Streptomyces avermitilis MA-4680 1210648 NP_824210.1 CDS SAV_3034 NC_003155.4 3792275 3793255 R hypothetical protein complement(3792275..3793255) Streptomyces avermitilis MA-4680 1214170 NP_824211.1 CDS SAV_3035 NC_003155.4 3793397 3794725 R PF01966: HD domain; lipoprotein complement(3793397..3794725) Streptomyces avermitilis MA-4680 1214171 NP_824212.1 CDS SAV_3036 NC_003155.4 3794722 3796161 R PF01966: HD domain; hypothetical protein complement(3794722..3796161) Streptomyces avermitilis MA-4680 1214172 NP_824213.1 CDS SAV_3037 NC_003155.4 3796337 3796648 R anti-sigma factor complement(3796337..3796648) Streptomyces avermitilis MA-4680 1214173 NP_824214.1 CDS sig22 NC_003155.4 3796645 3797328 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(3796645..3797328) Streptomyces avermitilis MA-4680 1210649 NP_824215.1 CDS SAV_3039 NC_003155.4 3797574 3798209 R hypothetical protein complement(3797574..3798209) Streptomyces avermitilis MA-4680 1214174 NP_824216.1 CDS SAV_3040 NC_003155.4 3798211 3799050 R PF02586: Uncharacterised ACR, COG2135; hypothetical protein complement(3798211..3799050) Streptomyces avermitilis MA-4680 1214175 NP_824217.1 CDS SAV_3041 NC_003155.4 3799157 3799888 D integral membrane protein 3799157..3799888 Streptomyces avermitilis MA-4680 1214176 NP_824218.1 CDS aroA NC_003155.4 3800068 3801408 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 3800068..3801408 Streptomyces avermitilis MA-4680 1210650 NP_824219.1 CDS SAV_3043 NC_003155.4 3801425 3802435 D PF03193: Protein of unknown function, DUF258; hypothetical protein 3801425..3802435 Streptomyces avermitilis MA-4680 1214177 NP_824220.1 CDS sugE NC_003155.4 3802556 3802879 D SMR-type multi-drug efflux transporter 3802556..3802879 Streptomyces avermitilis MA-4680 1214178 NP_824221.1 CDS SAV_3045 NC_003155.4 3802902 3804689 R ABC transporter ATP-binding protein complement(3802902..3804689) Streptomyces avermitilis MA-4680 1214179 NP_824222.1 CDS oppC1 NC_003155.4 3804695 3805603 R PF00528: Binding-protein-dependent transport system inner membrane component; peptide ABC transporter permease complement(3804695..3805603) Streptomyces avermitilis MA-4680 1210651 NP_824223.1 CDS oppB1 NC_003155.4 3805600 3806595 R peptide ABC transporter permease complement(3805600..3806595) Streptomyces avermitilis MA-4680 1210652 NP_824224.1 CDS oppA1 NC_003155.4 3806749 3808437 D extracellular solute-binding dependent transport lipoprotein 3806749..3808437 Streptomyces avermitilis MA-4680 1210653 NP_824225.1 CDS SAV_3049 NC_003155.4 3808424 3809056 R TetR family transcriptional regulator complement(3808424..3809056) Streptomyces avermitilis MA-4680 1214180 NP_824226.1 CDS SAV_3050 NC_003155.4 3809245 3810045 D fructose-1,6-bisphosphatase 3809245..3810045 Streptomyces avermitilis MA-4680 1214181 NP_824227.1 CDS SAV_3051 NC_003155.4 3810212 3810604 D PF00571: CBS domain; hypothetical protein 3810212..3810604 Streptomyces avermitilis MA-4680 1214182 NP_824228.1 CDS katA1 NC_003155.4 3810692 3812143 R catalase complement(3810692..3812143) Streptomyces avermitilis MA-4680 1210654 NP_824229.1 CDS catR NC_003155.4 3812287 3812703 D hydrogen peroxide sensitive repressor 3812287..3812703 Streptomyces avermitilis MA-4680 1210655 NP_824230.1 CDS SAV_3054 NC_003155.4 3813377 3815227 R PF00515: TPR Domain; hypothetical protein complement(3813377..3815227) Streptomyces avermitilis MA-4680 1214183 NP_824231.1 CDS SAV_3055 NC_003155.4 3815575 3818571 R PF03699: Uncharacterised protein family (UPF0182); integral membrane protein complement(3815575..3818571) Streptomyces avermitilis MA-4680 1214184 NP_824232.1 CDS SAV_3056 NC_003155.4 3818730 3819278 D hypothetical protein 3818730..3819278 Streptomyces avermitilis MA-4680 1214185 NP_824233.1 CDS SAV_3057 NC_003155.4 3819427 3820524 R PF00595: PDZ domain (Also known as DHR or GLGF); protein complement(3819427..3820524) Streptomyces avermitilis MA-4680 1214186 NP_824234.1 CDS SAV_3058 NC_003155.4 3820609 3820773 R hypothetical protein complement(3820609..3820773) Streptomyces avermitilis MA-4680 1214187 NP_824235.1 CDS moaE NC_003155.4 3820914 3821375 R molybdopterin biosynthesis protein E complement(3820914..3821375) Streptomyces avermitilis MA-4680 1210658 NP_824236.1 CDS SAV_3060 NC_003155.4 3821579 3822691 R PF01370: NAD dependent epimerase/dehydratase family; hypothetical protein complement(3821579..3822691) Streptomyces avermitilis MA-4680 1214188 NP_824237.1 CDS SAV_3061 NC_003155.4 3822882 3824333 D hypothetical protein 3822882..3824333 Streptomyces avermitilis MA-4680 1214189 NP_824238.1 CDS SAV_3062 NC_003155.4 3824330 3824851 D PF00293: NUDIX domain; hypothetical protein 3824330..3824851 Streptomyces avermitilis MA-4680 1214190 NP_824239.1 CDS SAV_3063 NC_003155.4 3824933 3825688 R PF01987: Protein of unknown function DUF124; hypothetical protein complement(3824933..3825688) Streptomyces avermitilis MA-4680 1214191 NP_824240.1 CDS SAV_3064 NC_003155.4 3825705 3826385 R PF01987: Protein of unknown function DUF124; hypothetical protein complement(3825705..3826385) Streptomyces avermitilis MA-4680 1214192 NP_824241.1 CDS SAV_3065 NC_003155.4 3826397 3828073 R PF01987: Protein of unknown function DUF124; hypothetical protein complement(3826397..3828073) Streptomyces avermitilis MA-4680 1214193 NP_824242.1 CDS SAV_3066 NC_003155.4 3828199 3828642 R PF01863: Protein of unknown function DUF45; hypothetical protein complement(3828199..3828642) Streptomyces avermitilis MA-4680 1214194 NP_824243.1 CDS SAV_3067 NC_003155.4 3829013 3830236 D PF00899: ThiF family; hypothetical protein 3829013..3830236 Streptomyces avermitilis MA-4680 1214195 NP_824244.1 CDS SAV_3068 NC_003155.4 3830229 3831584 D ABC transporter ATP-binding protein 3830229..3831584 Streptomyces avermitilis MA-4680 1214196 NP_824245.1 CDS SAV_3069 NC_003155.4 3831857 3832180 R hypothetical protein complement(3831857..3832180) Streptomyces avermitilis MA-4680 1214197 NP_824246.1 CDS SAV_3070 NC_003155.4 3832177 3832545 R WhiB-family transcriptional regulator complement(3832177..3832545) Streptomyces avermitilis MA-4680 1214198 NP_824247.1 CDS SAV_3071 NC_003155.4 3832722 3833069 R hypothetical protein complement(3832722..3833069) Streptomyces avermitilis MA-4680 1214199 NP_824248.1 CDS uvrD4 NC_003155.4 3833208 3835520 R ATP-dependent DNA helicase complement(3833208..3835520) Streptomyces avermitilis MA-4680 1210659 NP_824249.1 CDS SAV_3073 NC_003155.4 3835666 3835908 D glutaredoxin-like protein 3835666..3835908 Streptomyces avermitilis MA-4680 1214200 NP_824250.1 CDS SAV_3074 NC_003155.4 3836030 3836977 R PF00293: NUDIX domain; hypothetical protein complement(3836030..3836977) Streptomyces avermitilis MA-4680 1214201 NP_824251.1 CDS SAV_3075 NC_003155.4 3837142 3838545 R PF01546: Peptidase family M20/M25/M40; peptidase complement(3837142..3838545) Streptomyces avermitilis MA-4680 1214202 NP_824252.1 CDS uvrD3 NC_003155.4 3838556 3842164 R ATP-dependent DNA helicase complement(3838556..3842164) Streptomyces avermitilis MA-4680 1210660 NP_824253.1 CDS uvrD2 NC_003155.4 3842216 3845605 R ATP-dependent DNA helicase complement(3842216..3845605) Streptomyces avermitilis MA-4680 1210661 NP_824254.1 CDS SAV_3078 NC_003155.4 3845872 3846345 R PF01035: 6-O-methylguanine DNA methyltransferase, DNA binding domain; hypothetical protein complement(3845872..3846345) Streptomyces avermitilis MA-4680 1214203 NP_824255.1 CDS SAV_3079 NC_003155.4 3846424 3849318 D PF03706: Uncharacterised protein family (UPF0104); integral membrane protein 3846424..3849318 Streptomyces avermitilis MA-4680 1214204 NP_824256.1 CDS SAV_3080 NC_003155.4 3849387 3850937 D PF00561: alpha/beta hydrolase fold; protease 3849387..3850937 Streptomyces avermitilis MA-4680 1214205 NP_824257.1 CDS SAV_3081 NC_003155.4 3851057 3852610 D PF00561: alpha/beta hydrolase fold; protease 3851057..3852610 Streptomyces avermitilis MA-4680 1214206 NP_824258.1 CDS SAV_3082 NC_003155.4 3852673 3853851 R The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; molybdopterin biosynthesis-like protein MoeZ complement(3852673..3853851) Streptomyces avermitilis MA-4680 1214207 NP_824259.1 CDS SAV_3083 NC_003155.4 3853915 3854664 R hypothetical protein complement(3853915..3854664) Streptomyces avermitilis MA-4680 1214208 NP_824260.1 CDS SAV_3084 NC_003155.4 3854652 3855611 R NDP-hexose 4-ketoreductase complement(3854652..3855611) Streptomyces avermitilis MA-4680 1214209 NP_824261.1 CDS SAV_3085 NC_003155.4 3855812 3856843 R hypothetical protein complement(3855812..3856843) Streptomyces avermitilis MA-4680 1214210 NP_824262.1 CDS SAV_3086 NC_003155.4 3857047 3858975 R glycosyltransferase complement(3857047..3858975) Streptomyces avermitilis MA-4680 1214211 NP_824263.1 CDS SAV_3087 NC_003155.4 3859166 3860767 R ABC transporter ATP-binding protein complement(3859166..3860767) Streptomyces avermitilis MA-4680 1214212 NP_824264.1 CDS SAV_3088 NC_003155.4 3860764 3861762 R oligopeptide transport; ABC transporter complement(3860764..3861762) Streptomyces avermitilis MA-4680 1214213 NP_824265.1 CDS SAV_3089 NC_003155.4 3861759 3862841 R oligopeptide transport; ABC transporter complement(3861759..3862841) Streptomyces avermitilis MA-4680 1214214 NP_824266.1 CDS SAV_3090 NC_003155.4 3862846 3864564 R oligopeptide transport; ABC transporter substrate-binding protein complement(3862846..3864564) Streptomyces avermitilis MA-4680 1214215 NP_824267.1 CDS SAV_3091 NC_003155.4 3864860 3866410 R hypothetical protein complement(3864860..3866410) Streptomyces avermitilis MA-4680 1214216 NP_824268.1 CDS SAV_3092 NC_003155.4 3866419 3867456 R PF00561: alpha/beta hydrolase fold; hydrolase complement(3866419..3867456) Streptomyces avermitilis MA-4680 1214217 NP_824269.1 CDS SAV_3093 NC_003155.4 3867692 3867913 D hypothetical protein 3867692..3867913 Streptomyces avermitilis MA-4680 1214218 NP_824270.1 CDS SAV_3094 NC_003155.4 3868223 3868864 D TetR family transcriptional regulator 3868223..3868864 Streptomyces avermitilis MA-4680 1214219 NP_824271.1 CDS SAV_3095 NC_003155.4 3868964 3869248 D hypothetical protein 3868964..3869248 Streptomyces avermitilis MA-4680 1214220 NP_824272.1 CDS SAV_3096 NC_003155.4 3869353 3869706 D hypothetical protein 3869353..3869706 Streptomyces avermitilis MA-4680 1214221 NP_824273.1 CDS SAV_3097 NC_003155.4 3869891 3870637 R hypothetical protein complement(3869891..3870637) Streptomyces avermitilis MA-4680 1214222 NP_824274.1 CDS rhlE NC_003155.4 3871098 3873377 D PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase 3871098..3873377 Streptomyces avermitilis MA-4680 1210662 NP_824275.1 CDS SAV_3099 NC_003155.4 3873623 3874495 D PF00561: alpha/beta hydrolase fold; hydrolase 3873623..3874495 Streptomyces avermitilis MA-4680 1214223 NP_824276.1 CDS SAV_3100 NC_003155.4 3874618 3875514 R hypothetical protein complement(3874618..3875514) Streptomyces avermitilis MA-4680 1214224 NP_824277.1 CDS SAV_3101 NC_003155.4 3875749 3875925 D hypothetical protein 3875749..3875925 Streptomyces avermitilis MA-4680 1214225 NP_824278.1 CDS SAV_3102 NC_003155.4 3876042 3876647 R PF01914: MarC family integral membrane protein; integral membrane protein complement(3876042..3876647) Streptomyces avermitilis MA-4680 1214226 NP_824279.1 CDS SAV_3103 NC_003155.4 3876807 3877673 R PF02231: PHP domain N-terminal region; hypothetical protein complement(3876807..3877673) Streptomyces avermitilis MA-4680 1214227 NP_824280.1 CDS SAV_3104 NC_003155.4 3877876 3878517 R hypothetical protein complement(3877876..3878517) Streptomyces avermitilis MA-4680 1214228 NP_824281.1 CDS SAV_3105 NC_003155.4 3878805 3878993 R hypothetical protein complement(3878805..3878993) Streptomyces avermitilis MA-4680 1214229 NP_824282.1 CDS SAV_3106 NC_003155.4 3879026 3879610 R hypothetical protein complement(3879026..3879610) Streptomyces avermitilis MA-4680 1214230 NP_824283.1 CDS corA2 NC_003155.4 3880153 3881268 D metal-transport protein 3880153..3881268 Streptomyces avermitilis MA-4680 1214231 NP_824284.1 CDS SAV_3108 NC_003155.4 3881292 3881834 D hypothetical protein 3881292..3881834 Streptomyces avermitilis MA-4680 1214232 NP_824285.1 CDS SAV_3109 NC_003155.4 3882041 3882805 R lipoprotein complement(3882041..3882805) Streptomyces avermitilis MA-4680 1214233 NP_824286.1 CDS SAV_3110 NC_003155.4 3883056 3884354 D magnesium (Mg2+) transporter 3883056..3884354 Streptomyces avermitilis MA-4680 1214234 NP_824287.1 CDS SAV_3111 NC_003155.4 3884344 3884940 D PF06210: Protein of unknown function (DUF1003); hypothetical protein 3884344..3884940 Streptomyces avermitilis MA-4680 1214235 NP_824288.1 CDS SAV_3112 NC_003155.4 3884984 3886117 D ATP-binding protein 3884984..3886117 Streptomyces avermitilis MA-4680 1214236 NP_824289.1 CDS SAV_3113 NC_003155.4 3886257 3886991 R hypothetical protein complement(3886257..3886991) Streptomyces avermitilis MA-4680 1214237 NP_824290.1 CDS SAV_3114 NC_003155.4 3887259 3887705 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(3887259..3887705) Streptomyces avermitilis MA-4680 1214238 NP_824291.1 CDS SAV_3115 NC_003155.4 3887910 3889769 R PF00089: Trypsin; serine protease complement(3887910..3889769) Streptomyces avermitilis MA-4680 1214239 NP_824292.1 CDS SAV_3116 NC_003155.4 3890222 3891226 R hypothetical protein complement(3890222..3891226) Streptomyces avermitilis MA-4680 1214240 NP_824293.1 CDS sig23 NC_003155.4 3891223 3891882 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence; RNA polymerase sigma factor SigE complement(3891223..3891882) Streptomyces avermitilis MA-4680 1210663 NP_824294.1 CDS SAV_3118 NC_003155.4 3892325 3892849 D O-methyltransferase 3892325..3892849 Streptomyces avermitilis MA-4680 1214241 NP_824295.1 CDS SAV_3119 NC_003155.4 3893015 3893260 R hypothetical protein complement(3893015..3893260) Streptomyces avermitilis MA-4680 1214242 NP_824296.1 CDS SAV_3120 NC_003155.4 3893559 3894362 D enoyl-CoA hydratase/isomerase 3893559..3894362 Streptomyces avermitilis MA-4680 1214243 NP_824297.1 CDS tagA NC_003155.4 3894382 3894963 R DNA-3-methyladenine glycosylase I complement(3894382..3894963) Streptomyces avermitilis MA-4680 1210664 NP_824298.1 CDS SAV_3122 NC_003155.4 3894960 3895316 R protein complement(3894960..3895316) Streptomyces avermitilis MA-4680 1214244 NP_824299.1 CDS folP1 NC_003155.4 3895549 3896409 D dihydropteroate synthase 3895549..3896409 Streptomyces avermitilis MA-4680 1210665 NP_824300.1 CDS SAV_3124 NC_003155.4 3896455 3897213 R PF03641: Possible lysine decarboxylase; hypothetical protein complement(3896455..3897213) Streptomyces avermitilis MA-4680 1214245 NP_824301.1 CDS dapE NC_003155.4 3897321 3898400 R catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase complement(3897321..3898400) Streptomyces avermitilis MA-4680 1210666 NP_824302.1 CDS SAV_3126 NC_003155.4 3898600 3899463 D hypothetical protein 3898600..3899463 Streptomyces avermitilis MA-4680 1214246 NP_824303.1 CDS SAV_3127 NC_003155.4 3899804 3900253 D ATP-binding protein 3899804..3900253 Streptomyces avermitilis MA-4680 1214247 NP_824304.1 CDS aspB2 NC_003155.4 3900319 3901413 R catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase complement(3900319..3901413) Streptomyces avermitilis MA-4680 1214248 NP_824305.1 CDS fdxD NC_003155.4 3901642 3901962 R ferredoxin complement(3901642..3901962) Streptomyces avermitilis MA-4680 1210667 NP_824306.1 CDS SAV_3130 NC_003155.4 3902103 3903476 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 3902103..3903476 Streptomyces avermitilis MA-4680 1214249 NP_824307.1 CDS SAV_3131 NC_003155.4 3903473 3904345 D hypothetical protein 3903473..3904345 Streptomyces avermitilis MA-4680 1214250 NP_824308.1 CDS SAV_3132 NC_003155.4 3904364 3904978 R two-component system response regulator complement(3904364..3904978) Streptomyces avermitilis MA-4680 1214251 NP_824309.1 CDS SAV_3133 NC_003155.4 3904989 3906146 R two-component system sensor kinase complement(3904989..3906146) Streptomyces avermitilis MA-4680 1214252 NP_824310.1 CDS SAV_3134 NC_003155.4 3906197 3906955 R ABC transporter permease complement(3906197..3906955) Streptomyces avermitilis MA-4680 1214253 NP_824311.1 CDS SAV_3135 NC_003155.4 3906952 3907860 R ABC transporter ATP-binding protein complement(3906952..3907860) Streptomyces avermitilis MA-4680 1214254 NP_824312.1 CDS SAV_3136 NC_003155.4 3908162 3910441 R hypothetical protein complement(3908162..3910441) Streptomyces avermitilis MA-4680 1214255 NP_824313.1 CDS SAV_3137 NC_003155.4 3910607 3911026 R integral membrane protein complement(3910607..3911026) Streptomyces avermitilis MA-4680 1214256 NP_824314.1 CDS mshB NC_003155.4 3911026 3911910 R mycothiol biosynthesis; N-acetyl-1-D-myo-inosityl-2-amino-2- deoxy-alpha-D-glucopyranoside deacetylase complement(3911026..3911910) Streptomyces avermitilis MA-4680 1214257 NP_824315.1 CDS SAV_3139 NC_003155.4 3912070 3912966 R hypothetical protein complement(3912070..3912966) Streptomyces avermitilis MA-4680 1214258 NP_824316.1 CDS SAV_3140 NC_003155.4 3913164 3913658 R regulatory protein complement(3913164..3913658) Streptomyces avermitilis MA-4680 1214259 NP_824317.1 CDS SAV_3141 NC_003155.4 3913789 3914658 D DNA-binding protein 3913789..3914658 Streptomyces avermitilis MA-4680 1214260 NP_824318.1 CDS SAV_3142 NC_003155.4 3914655 3914867 D PF04149: Domain of unknown function (DUF397); hypothetical protein 3914655..3914867 Streptomyces avermitilis MA-4680 1214261 NP_824319.1 CDS SAV_3143 NC_003155.4 3914978 3915172 R protein complement(3914978..3915172) Streptomyces avermitilis MA-4680 1214262 NP_824320.1 CDS SAV_3144 NC_003155.4 3915360 3917492 D PF00326: Prolyl oligopeptidase family; peptidase 3915360..3917492 Streptomyces avermitilis MA-4680 1214263 NP_824321.1 CDS SAV_3145 NC_003155.4 3917642 3918727 R peptide ABC transporter ATP-binding protein complement(3917642..3918727) Streptomyces avermitilis MA-4680 1214264 NP_824322.1 CDS dppD NC_003155.4 3918720 3919703 R peptide ABC transporter ATP-binding protein complement(3918720..3919703) Streptomyces avermitilis MA-4680 1210668 NP_824323.1 CDS oppC2 NC_003155.4 3919711 3920631 R oligopeptide ABC transporter permease complement(3919711..3920631) Streptomyces avermitilis MA-4680 1210669 NP_824324.1 CDS oppB2 NC_003155.4 3920681 3921604 R oligopeptide ABC transporter substrate-binding protein complement(3920681..3921604) Streptomyces avermitilis MA-4680 1210670 NP_824325.1 CDS oppA2 NC_003155.4 3921659 3923281 R oligopeptide ABC transporter substrate-binding protein complement(3921659..3923281) Streptomyces avermitilis MA-4680 1210671 NP_824326.1 CDS bldKA1 NC_003155.4 3923776 3924765 D ABC transporter periplasmic component; ABC transporter permease 3923776..3924765 Streptomyces avermitilis MA-4680 1210672 NP_824327.1 CDS bldKB1 NC_003155.4 3924847 3926610 D ABC transporter periplasmic component; ABC transporter 3924847..3926610 Streptomyces avermitilis MA-4680 1210673 NP_824328.1 CDS bldKC1 NC_003155.4 3926736 3927716 D ABC transporter periplasmic component; ABC transporter permease 3926736..3927716 Streptomyces avermitilis MA-4680 1210674 NP_824329.1 CDS bldKD1 NC_003155.4 3927777 3928847 D ABC transporter ATP-binding protein; ABC transporter ATPase 3927777..3928847 Streptomyces avermitilis MA-4680 1210675 NP_824330.1 CDS bldKE1 NC_003155.4 3928871 3929917 D ABC transporter ATP-binding protein 3928871..3929917 Streptomyces avermitilis MA-4680 1210676 NP_824331.1 CDS SAV_3155 NC_003155.4 3930088 3930255 R nrps3 gene cluster; MbtH-like protein complement(3930088..3930255) Streptomyces avermitilis MA-4680 1214265 NP_824332.1 CDS nrps3-1 NC_003155.4 3930306 3932183 R nrps3 gene cluster; non-ribosomal peptide synthetase complement(3930306..3932183) Streptomyces avermitilis MA-4680 1214266 NP_824333.1 CDS SAV_3157 NC_003155.4 3932261 3933553 R nrps3 gene cluster, PF07690: Major Facilitator Superfamily; export protein complement(3932261..3933553) Streptomyces avermitilis MA-4680 1214267 NP_824334.1 CDS nrps3-2 NC_003155.4 3933613 3934425 R nrps3 gene cluster; non-ribosomal peptide synthetase complement(3933613..3934425) Streptomyces avermitilis MA-4680 1214268 NP_824335.1 CDS nrps3-3 NC_003155.4 3934439 3937489 R nrps3 gene cluster; non-ribosomal peptide synthetase complement(3934439..3937489) Streptomyces avermitilis MA-4680 1214269 NP_824336.1 CDS SAV_3160 NC_003155.4 3937627 3938730 R nrps3 gene cluster; aminotransferase complement(3937627..3938730) Streptomyces avermitilis MA-4680 1214270 NP_824337.1 CDS dapF NC_003155.4 3938765 3939688 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(3938765..3939688) Streptomyces avermitilis MA-4680 1210677 NP_824338.1 CDS SAV_3162 NC_003155.4 3939735 3940430 R hypothetical protein complement(3939735..3940430) Streptomyces avermitilis MA-4680 1214271 NP_824339.1 CDS SAV_3163 NC_003155.4 3940462 3941439 R hypothetical protein complement(3940462..3941439) Streptomyces avermitilis MA-4680 1214272 NP_824340.1 CDS SAV_3164 NC_003155.4 3941820 3942062 R hypothetical protein complement(3941820..3942062) Streptomyces avermitilis MA-4680 1214273 NP_824341.1 CDS SAV_3165 NC_003155.4 3942121 3943161 D LuxR family transcriptional regulator 3942121..3943161 Streptomyces avermitilis MA-4680 1214274 NP_824342.1 CDS SAV_3166 NC_003155.4 3943089 3944108 R AraC family transcription regulator complement(3943089..3944108) Streptomyces avermitilis MA-4680 1214275 NP_824343.1 CDS SAV_3167 NC_003155.4 3944179 3944508 D hypothetical protein 3944179..3944508 Streptomyces avermitilis MA-4680 1214276 NP_824344.1 CDS SAV_3168 NC_003155.4 3944522 3945043 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(3944522..3945043) Streptomyces avermitilis MA-4680 1214277 NP_824345.1 CDS SAV_3169 NC_003155.4 3945049 3945456 R hypothetical protein complement(3945049..3945456) Streptomyces avermitilis MA-4680 1214278 NP_824346.1 CDS SAV_3170 NC_003155.4 3945461 3945964 R PF04978: Protein of unknown function (DUF664); hypothetical protein complement(3945461..3945964) Streptomyces avermitilis MA-4680 1214279 NP_824347.1 CDS SAV_3171 NC_003155.4 3946132 3946872 D methyltransferase 3946132..3946872 Streptomyces avermitilis MA-4680 1214280 NP_824348.1 CDS bldKE2 NC_003155.4 3946897 3948111 R ABC transporter ATP-binding protein complement(3946897..3948111) Streptomyces avermitilis MA-4680 1210678 NP_824349.1 CDS bldKD2 NC_003155.4 3948185 3949246 R ABC transporter ATP-binding protein; ABC transporter ATPase complement(3948185..3949246) Streptomyces avermitilis MA-4680 1210679 NP_824350.1 CDS bldKC2 NC_003155.4 3949256 3950236 R ABC transporter periplasmic component; ABC transporter permease complement(3949256..3950236) Streptomyces avermitilis MA-4680 1210680 NP_824351.1 CDS bldKB2 NC_003155.4 3950336 3952147 R ABC transporter periplasmic component; ABC transporter complement(3950336..3952147) Streptomyces avermitilis MA-4680 1210681 NP_824352.1 CDS bldKA2 NC_003155.4 3952264 3953298 R ABC transporter periplasmic component; ABC transporter permease complement(3952264..3953298) Streptomyces avermitilis MA-4680 1210682 NP_824353.1 CDS typA NC_003155.4 3953896 3955803 R GTP-binding elongation factor complement(3953896..3955803) Streptomyces avermitilis MA-4680 1214281 NP_824354.1 CDS SAV_3178 NC_003155.4 3955987 3958224 R PF00497: Bacterial extracellular solute-binding proteins, family 3; lipoprotein complement(3955987..3958224) Streptomyces avermitilis MA-4680 1214282 NP_824355.1 CDS SAV_3179 NC_003155.4 3958634 3958921 D hypothetical protein 3958634..3958921 Streptomyces avermitilis MA-4680 1214283 NP_824356.1 CDS SAV_3180 NC_003155.4 3958978 3959799 D hypothetical protein 3958978..3959799 Streptomyces avermitilis MA-4680 1214284 NP_824357.1 CDS sdhA NC_003155.4 3959816 3961819 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 3959816..3961819 Streptomyces avermitilis MA-4680 1210683 NP_824358.1 CDS sdhB2 NC_003155.4 3961816 3962592 D catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; fumarate reductase iron-sulfur subunit 3961816..3962592 Streptomyces avermitilis MA-4680 1210684 NP_824359.1 CDS SAV_3183 NC_003155.4 3962688 3963926 R hypothetical protein complement(3962688..3963926) Streptomyces avermitilis MA-4680 1214285 NP_824360.1 CDS SAV_3184 NC_003155.4 3964078 3966321 D hypothetical protein 3964078..3966321 Streptomyces avermitilis MA-4680 1214286 NP_824361.1 CDS prpM3 NC_003155.4 3966409 3969351 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(3966409..3969351) Streptomyces avermitilis MA-4680 1214287 NP_824362.1 CDS SAV_3186 NC_003155.4 3969517 3969975 R regulatory protein complement(3969517..3969975) Streptomyces avermitilis MA-4680 1214288 NP_824363.1 CDS SAV_3187 NC_003155.4 3970140 3970532 R mutT-like protein complement(3970140..3970532) Streptomyces avermitilis MA-4680 1214289 NP_824364.1 CDS SAV_3188 NC_003155.4 3970606 3970788 R hypothetical protein complement(3970606..3970788) Streptomyces avermitilis MA-4680 1214290 NP_824365.1 CDS SAV_3189 NC_003155.4 3971116 3971868 R GntR family transcriptional regulator complement(3971116..3971868) Streptomyces avermitilis MA-4680 1214291 NP_824366.1 CDS SAV_3190 NC_003155.4 3972016 3973185 R hypothetical protein complement(3972016..3973185) Streptomyces avermitilis MA-4680 1214292 NP_824367.1 CDS thrC2 NC_003155.4 3973434 3974567 D threonine synthase 3973434..3974567 Streptomyces avermitilis MA-4680 1210685 NP_824368.1 CDS SAV_3192 NC_003155.4 3974801 3976906 R bifunctional protein complement(3974801..3976906) Streptomyces avermitilis MA-4680 1214293 NP_824369.1 CDS pptA3 NC_003155.4 3977231 3977905 R PF01648: 4'-phosphopantetheinyl transferase superfamily; phosphopantetheinyl transferase complement(3977231..3977905) Streptomyces avermitilis MA-4680 1210686 NP_824370.1 CDS SAV_3194 NC_003155.4 3977950 3978756 R PF00795: Carbon-nitrogen hydrolase; hydrolase complement(3977950..3978756) Streptomyces avermitilis MA-4680 1214294 NP_824371.1 CDS SAV_3195 NC_003155.4 3978837 3979130 R PF06063: Domain of unknown function (DUF931); hypothetical protein complement(3978837..3979130) Streptomyces avermitilis MA-4680 1214295 NP_824372.1 CDS SAV_3196 NC_003155.4 3979154 3980047 R PF03591: AzlC protein; hypothetical protein complement(3979154..3980047) Streptomyces avermitilis MA-4680 1214296 NP_824373.1 CDS nrps1-1 NC_003155.4 3980213 3985519 R nrps1 gene cluster; non-ribosomal peptide synthetase complement(3980213..3985519) Streptomyces avermitilis MA-4680 1214297 NP_824374.1 CDS nrps1-2 NC_003155.4 3985548 3989339 R nrps1 gene cluster; non-ribosomal peptide synthetase complement(3985548..3989339) Streptomyces avermitilis MA-4680 1214298 NP_824375.1 CDS nrps1-3 NC_003155.4 3989374 3992310 R nrps1 gene cluster; non-ribosomal peptide synthetase complement(3989374..3992310) Streptomyces avermitilis MA-4680 1214299 NP_824376.1 CDS SAV_3200 NC_003155.4 3992464 3993294 R nrps1 gene cluster, PF00106: short chain dehydrogenase; dehydrogenase complement(3992464..3993294) Streptomyces avermitilis MA-4680 1214300 NP_824377.1 CDS SAV_3201 NC_003155.4 3993291 3994004 R nrps1 gene cluster; thioesterase complement(3993291..3994004) Streptomyces avermitilis MA-4680 1214301 NP_824378.1 CDS SAV_3202 NC_003155.4 3994107 3994940 R nrps1 gene cluster; thioesterase complement(3994107..3994940) Streptomyces avermitilis MA-4680 1214302 NP_824379.1 CDS SAV_3203 NC_003155.4 3995124 3996191 D nrps1 gene cluster, LuxR-family; regulatory protein 3995124..3996191 Streptomyces avermitilis MA-4680 1214303 NP_824380.1 CDS SAV_3204 NC_003155.4 3996878 3997273 R hypothetical protein complement(3996878..3997273) Streptomyces avermitilis MA-4680 1214304 NP_824381.1 CDS SAV_3205 NC_003155.4 3997841 3998095 R homology to AviX3 Streptomyces viridochromogenes, PF06769: Protein of unknown function (DUF1224); hypothetical protein complement(3997841..3998095) Streptomyces avermitilis MA-4680 1214305 NP_824382.1 CDS SAV_3206 NC_003155.4 3998092 3998373 R homology to AviX2 Streptomyces viridochromogenes, PF02604: Phd_YefM; hypothetical protein complement(3998092..3998373) Streptomyces avermitilis MA-4680 1214306 NP_824383.1 CDS SAV_3207 NC_003155.4 3998574 3999662 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(3998574..3999662) Streptomyces avermitilis MA-4680 1214307 NP_824384.1 CDS SAV_3208 NC_003155.4 3999878 4000591 D hypothetical protein 3999878..4000591 Streptomyces avermitilis MA-4680 1214308 NP_824385.1 CDS ppgK NC_003155.4 4000786 4001532 R PF00480: ROK family; polyphosphate glucokinase complement(4000786..4001532) Streptomyces avermitilis MA-4680 1210687 NP_824386.1 CDS ispH NC_003155.4 4001562 4002578 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(4001562..4002578) Streptomyces avermitilis MA-4680 1210688 NP_824387.1 CDS xseA NC_003155.4 4002836 4004044 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 4002836..4004044 Streptomyces avermitilis MA-4680 1210689 NP_824388.1 CDS xseB NC_003155.4 4004054 4004296 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 4004054..4004296 Streptomyces avermitilis MA-4680 1210690 NP_824389.1 CDS SAV_3213 NC_003155.4 4004666 4005256 D PF00881: Nitroreductase family; hypothetical protein 4004666..4005256 Streptomyces avermitilis MA-4680 1214309 NP_824390.1 CDS SAV_3214 NC_003155.4 4005458 4005979 R protein complement(4005458..4005979) Streptomyces avermitilis MA-4680 1214310 NP_824391.1 CDS glpX NC_003155.4 4006107 4007141 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4006107..4007141 Streptomyces avermitilis MA-4680 1214311 NP_824392.1 CDS wblI NC_003155.4 4007271 4007642 R PF02467: Transcription factor WhiB; WhiB-family transcriptional regulator complement(4007271..4007642) Streptomyces avermitilis MA-4680 1210691 NP_824393.1 CDS SAV_3217 NC_003155.4 4007817 4008521 R hypothetical protein complement(4007817..4008521) Streptomyces avermitilis MA-4680 1214312 NP_824394.1 CDS fumB NC_003155.4 4008701 4010377 D fumarate hydratase class I 4008701..4010377 Streptomyces avermitilis MA-4680 1210692 NP_824395.1 CDS SAV_3219 NC_003155.4 4010565 4011002 D hypothetical protein 4010565..4011002 Streptomyces avermitilis MA-4680 1214313 NP_824396.1 CDS SAV_3220 NC_003155.4 4011015 4014206 D PF05729: NACHT domain; hypothetical protein 4011015..4014206 Streptomyces avermitilis MA-4680 1214314 NP_824397.1 CDS fumC NC_003155.4 4014275 4015678 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 4014275..4015678 Streptomyces avermitilis MA-4680 1210693 NP_824398.1 CDS SAV_3222 NC_003155.4 4015793 4016485 D PF04167: Protein of unknown function (DUF402); hypothetical protein 4015793..4016485 Streptomyces avermitilis MA-4680 1214315 NP_824399.1 CDS prpE2 NC_003155.4 4016768 4018918 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 4016768..4018918 Streptomyces avermitilis MA-4680 1214316 NP_824400.1 CDS katA2 NC_003155.4 4019075 4020538 D catalase 4019075..4020538 Streptomyces avermitilis MA-4680 1210694 NP_824401.1 CDS pbp2 NC_003155.4 4020616 4022949 R PF00912: Transglycosylase; penicillin-binding protein complement(4020616..4022949) Streptomyces avermitilis MA-4680 1210695 NP_824402.1 CDS SAV_3226 NC_003155.4 4023232 4024179 D PF01145: SPFH domain / Band 7 family; integral membrane protein 4023232..4024179 Streptomyces avermitilis MA-4680 1214317 NP_824403.1 CDS SAV_3227 NC_003155.4 4024176 4024439 D hypothetical protein 4024176..4024439 Streptomyces avermitilis MA-4680 1214318 NP_824404.1 CDS SAV_3228 NC_003155.4 4024588 4025115 D PadR-family transcriptional regulator 4024588..4025115 Streptomyces avermitilis MA-4680 1214319 NP_824405.1 CDS SAV_3229 NC_003155.4 4025112 4025798 D ABC transporter ATP-binding protein 4025112..4025798 Streptomyces avermitilis MA-4680 1214320 NP_824406.1 CDS SAV_3230 NC_003155.4 4025795 4028131 D PF02687: Predicted permease; integral membrane protein 4025795..4028131 Streptomyces avermitilis MA-4680 1214321 NP_824407.1 CDS oxyR NC_003155.4 4028192 4029202 R hydrogen peroxide sensing regulator complement(4028192..4029202) Streptomyces avermitilis MA-4680 1210696 NP_824408.1 CDS ahpC NC_003155.4 4029374 4029928 D alkyl hydroperoxide reductase 4029374..4029928 Streptomyces avermitilis MA-4680 1210697 NP_824409.1 CDS ahpD NC_003155.4 4029935 4030468 D alkylhydroperoxidase 4029935..4030468 Streptomyces avermitilis MA-4680 1210698 NP_824410.1 CDS SAV_3234 NC_003155.4 4030554 4031876 R PF01594: Domain of unknown function DUF20; integral membrane protein complement(4030554..4031876) Streptomyces avermitilis MA-4680 1214322 NP_824411.1 CDS SAV_3235 NC_003155.4 4032029 4032742 R PF06737: Transglycosylase-like domain; hypothetical protein complement(4032029..4032742) Streptomyces avermitilis MA-4680 1214323 NP_824412.1 CDS SAV_3236 NC_003155.4 4033150 4034475 R ATP-binding protein complement(4033150..4034475) Streptomyces avermitilis MA-4680 1214324 NP_824413.1 CDS uppS1 NC_003155.4 4034777 4035550 R catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(4034777..4035550) Streptomyces avermitilis MA-4680 1210699 NP_824414.1 CDS SAV_3238 NC_003155.4 4036211 4036801 D PF02643: Uncharacterized ACR, COG1430; hypothetical protein 4036211..4036801 Streptomyces avermitilis MA-4680 1214325 NP_824415.1 CDS SAV_3239 NC_003155.4 4037259 4038419 D hypothetical protein 4037259..4038419 Streptomyces avermitilis MA-4680 1214326 NP_824416.1 CDS SAV_3240 NC_003155.4 4038477 4039337 R hypothetical protein complement(4038477..4039337) Streptomyces avermitilis MA-4680 1214327 NP_824417.1 CDS SAV_3241 NC_003155.4 4039440 4039925 D PF04978: Protein of unknown function (DUF664); hypothetical protein 4039440..4039925 Streptomyces avermitilis MA-4680 1214328 NP_824418.1 CDS SAV_3242 NC_003155.4 4039968 4040474 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(4039968..4040474) Streptomyces avermitilis MA-4680 1214329 NP_824419.1 CDS SAV_3243 NC_003155.4 4040505 4041377 R FMNH2-utilizing oxygenase complement(4040505..4041377) Streptomyces avermitilis MA-4680 1214330 NP_824420.1 CDS SAV_3244 NC_003155.4 4041419 4042066 R PF01872: RibD C-terminal domain; hypothetical protein complement(4041419..4042066) Streptomyces avermitilis MA-4680 1214331 NP_824421.1 CDS SAV_3245 NC_003155.4 4042190 4042870 R PF00691: OmpA family; protein complement(4042190..4042870) Streptomyces avermitilis MA-4680 1214332 NP_824422.1 CDS SAV_3246 NC_003155.4 4042874 4043467 R hypothetical protein complement(4042874..4043467) Streptomyces avermitilis MA-4680 1214333 NP_824423.1 CDS SAV_3247 NC_003155.4 4043483 4044037 R hypothetical protein complement(4043483..4044037) Streptomyces avermitilis MA-4680 1214334 NP_824424.1 CDS SAV_3248 NC_003155.4 4044097 4044312 R hypothetical protein complement(4044097..4044312) Streptomyces avermitilis MA-4680 1214335 NP_824425.1 CDS SAV_3249 NC_003155.4 4044439 4045170 R two-component system response regulator complement(4044439..4045170) Streptomyces avermitilis MA-4680 1214336 NP_824426.1 CDS SAV_3250 NC_003155.4 4045163 4046581 R two-component system sensor kinase complement(4045163..4046581) Streptomyces avermitilis MA-4680 1214337 NP_824427.1 CDS SAV_3251 NC_003155.4 4046593 4047498 R PF00482: Bacterial type II secretion system protein F domain; hypothetical protein complement(4046593..4047498) Streptomyces avermitilis MA-4680 1214338 NP_824428.1 CDS SAV_3252 NC_003155.4 4047510 4048451 R PF00482: Bacterial type II secretion system protein F domain; hypothetical protein complement(4047510..4048451) Streptomyces avermitilis MA-4680 1214339 NP_824429.1 CDS SAV_3253 NC_003155.4 4048501 4049841 R secretory protein complement(4048501..4049841) Streptomyces avermitilis MA-4680 1214340 NP_824430.1 CDS SAV_3254 NC_003155.4 4049931 4050083 R hypothetical protein complement(4049931..4050083) Streptomyces avermitilis MA-4680 1214341 NP_824431.1 CDS minD1 NC_003155.4 4050333 4051940 R septum site-determining protein complement(4050333..4051940) Streptomyces avermitilis MA-4680 1210700 NP_824432.1 CDS SAV_3256 NC_003155.4 4052009 4052638 R PF06981: Flp pilus assembly protein CpaB; hypothetical protein complement(4052009..4052638) Streptomyces avermitilis MA-4680 1214342 NP_824433.1 CDS SAV_3257 NC_003155.4 4052801 4053688 R hypothetical protein complement(4052801..4053688) Streptomyces avermitilis MA-4680 1214343 NP_824434.1 CDS chiA1 NC_003155.4 4054020 4055759 D chitinase A 4054020..4055759 Streptomyces avermitilis MA-4680 1210701 NP_824435.1 CDS SAV_3259 NC_003155.4 4056529 4056882 D hypothetical protein 4056529..4056882 Streptomyces avermitilis MA-4680 1214344 NP_824436.1 CDS SAV_3260 NC_003155.4 4056905 4057366 D hypothetical protein 4056905..4057366 Streptomyces avermitilis MA-4680 1214345 NP_824437.1 CDS SAV_3261 NC_003155.4 4057820 4059073 D hypothetical protein 4057820..4059073 Streptomyces avermitilis MA-4680 1214346 NP_824438.1 CDS SAV_3262 NC_003155.4 4059066 4059590 R regulatory protein complement(4059066..4059590) Streptomyces avermitilis MA-4680 1214347 NP_824439.1 CDS SAV_3263 NC_003155.4 4059832 4060683 D DNA-binding protein 4059832..4060683 Streptomyces avermitilis MA-4680 1214348 NP_824440.1 CDS SAV_3264 NC_003155.4 4060692 4060886 D hypothetical protein 4060692..4060886 Streptomyces avermitilis MA-4680 1214349 NP_824441.1 CDS SAV_3265 NC_003155.4 4060888 4061418 R hypothetical protein complement(4060888..4061418) Streptomyces avermitilis MA-4680 1214350 NP_824442.1 CDS SAV_3266 NC_003155.4 4061623 4062975 D PF00246: Zinc carboxypeptidase; carboxypeptidase 4061623..4062975 Streptomyces avermitilis MA-4680 1214351 NP_824443.1 CDS SAV_3267 NC_003155.4 4063001 4063606 R hypothetical protein complement(4063001..4063606) Streptomyces avermitilis MA-4680 1214352 NP_824444.1 CDS SAV_3268 NC_003155.4 4063733 4065298 R PF00004: ATPase family associated with various cellular activities (AAA); ATPase complement(4063733..4065298) Streptomyces avermitilis MA-4680 1214353 NP_824445.1 CDS SAV_3269 NC_003155.4 4065495 4066115 R hypothetical protein complement(4065495..4066115) Streptomyces avermitilis MA-4680 1214354 NP_824446.1 CDS SAV_3270 NC_003155.4 4066470 4068242 R PF04956: Conjugal transfer protein TrbC; hypothetical protein complement(4066470..4068242) Streptomyces avermitilis MA-4680 1214355 NP_824447.1 CDS SAV_3271 NC_003155.4 4068315 4068863 R hypothetical protein complement(4068315..4068863) Streptomyces avermitilis MA-4680 1214356 NP_824448.1 CDS SAV_3272 NC_003155.4 4069022 4071052 D PF00656: Caspase domain; hypothetical protein 4069022..4071052 Streptomyces avermitilis MA-4680 1214357 NP_824449.1 CDS SAV_3273 NC_003155.4 4071033 4075478 R hypothetical protein complement(4071033..4075478) Streptomyces avermitilis MA-4680 1214358 NP_824450.1 CDS SAV_3274 NC_003155.4 4075537 4076190 R hypothetical protein complement(4075537..4076190) Streptomyces avermitilis MA-4680 1214359 NP_824451.1 CDS SAV_3275 NC_003155.4 4076193 4076861 R hypothetical protein complement(4076193..4076861) Streptomyces avermitilis MA-4680 1214360 NP_824452.1 CDS SAV_3276 NC_003155.4 4076881 4078074 R hypothetical protein complement(4076881..4078074) Streptomyces avermitilis MA-4680 1214361 NP_824453.1 CDS SAV_3277 NC_003155.4 4078192 4079679 R PF02447: GntP family permease; low-affinity gluconate transporter complement(4078192..4079679) Streptomyces avermitilis MA-4680 1214362 NP_824454.1 CDS SAV_3278 NC_003155.4 4079800 4080219 R PF01042: Endoribonuclease L-PSP; hypothetical protein complement(4079800..4080219) Streptomyces avermitilis MA-4680 1214363 NP_824455.1 CDS SAV_3279 NC_003155.4 4080229 4081023 R IclR family transcriptional regulator complement(4080229..4081023) Streptomyces avermitilis MA-4680 1214364 NP_824456.1 CDS kdgK NC_003155.4 4081020 4082105 R 2-oxo-3-deoxygluconate kinase complement(4081020..4082105) Streptomyces avermitilis MA-4680 1210702 NP_824457.1 CDS SAV_3281 NC_003155.4 4082240 4083511 D PF01168: Alanine racemase, N-terminal domain; D-amino acid deaminase 4082240..4083511 Streptomyces avermitilis MA-4680 1214365 NP_824458.1 CDS SAV_3282 NC_003155.4 4083587 4085179 D PF01979: Amidohydrolase family; D-aminoacylase 4083587..4085179 Streptomyces avermitilis MA-4680 1214366 NP_824459.1 CDS SAV_3283 NC_003155.4 4085198 4085839 R hypothetical protein complement(4085198..4085839) Streptomyces avermitilis MA-4680 1214367 NP_824460.1 CDS SAV_3284 NC_003155.4 4086337 4087140 R hypothetical protein complement(4086337..4087140) Streptomyces avermitilis MA-4680 1214368 NP_824461.1 CDS aspB3 NC_003155.4 4087192 4088403 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 4087192..4088403 Streptomyces avermitilis MA-4680 1214369 NP_824462.1 CDS SAV_3286 NC_003155.4 4088541 4088960 D hypothetical protein 4088541..4088960 Streptomyces avermitilis MA-4680 1214370 NP_824463.1 CDS pck NC_003155.4 4089495 4091318 R catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase complement(4089495..4091318) Streptomyces avermitilis MA-4680 1210703 NP_824464.1 CDS SAV_3288 NC_003155.4 4091675 4092388 D PF03006: Uncharacterised protein family (Hly-III / UPF0073); hypothetical protein 4091675..4092388 Streptomyces avermitilis MA-4680 1214371 NP_824465.1 CDS SAV_3289 NC_003155.4 4092550 4094124 D similar to monensin resistance protein MonT, PF07690: Major Facilitator Superfamily; integral membrane efflux protein 4092550..4094124 Streptomyces avermitilis MA-4680 1214372 NP_824466.1 CDS SAV_3290 NC_003155.4 4094130 4094792 D TetR family transcriptional regulator 4094130..4094792 Streptomyces avermitilis MA-4680 1214373 NP_824467.1 CDS SAV_3291 NC_003155.4 4094797 4095522 D PF01927: Protein of unknown function DUF82; hypothetical protein 4094797..4095522 Streptomyces avermitilis MA-4680 1214374 NP_824468.1 CDS SAV_3292 NC_003155.4 4095519 4097792 R PF07250: Glyoxal oxidase N-terminus; hypothetical protein complement(4095519..4097792) Streptomyces avermitilis MA-4680 1214375 NP_824469.1 CDS dpm NC_003155.4 4097945 4099147 R PF00535: Glycosyl transferase; dolichol-phosphate mannosyltransferase complement(4097945..4099147) Streptomyces avermitilis MA-4680 1210704 NP_824470.1 CDS SAV_3294 NC_003155.4 4099144 4100784 R PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; hypothetical protein complement(4099144..4100784) Streptomyces avermitilis MA-4680 1214376 NP_824471.1 CDS SAV_3295 NC_003155.4 4100781 4102091 R PF00535: Glycosyl transferase; glycosyl transferase complement(4100781..4102091) Streptomyces avermitilis MA-4680 1214377 NP_824472.1 CDS SAV_3296 NC_003155.4 4102247 4104274 R PF03190: Protein of unknown function, DUF255; hypothetical protein complement(4102247..4104274) Streptomyces avermitilis MA-4680 1214378 NP_824473.1 CDS SAV_3297 NC_003155.4 4104456 4107692 D regulatory protein 4104456..4107692 Streptomyces avermitilis MA-4680 1214379 NP_824474.1 CDS SAV_3298 NC_003155.4 4107799 4108113 R hypothetical protein complement(4107799..4108113) Streptomyces avermitilis MA-4680 1214380 NP_824475.1 CDS SAV_3299 NC_003155.4 4108126 4108998 R PF02585: Uncharacterised LmbE-like protein, COG2120; hypothetical protein complement(4108126..4108998) Streptomyces avermitilis MA-4680 1214381 NP_824476.1 CDS SAV_3300 NC_003155.4 4109154 4109552 D hypothetical protein 4109154..4109552 Streptomyces avermitilis MA-4680 1214382 NP_824477.1 CDS greA NC_003155.4 4109721 4110218 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 4109721..4110218 Streptomyces avermitilis MA-4680 1210705 NP_824478.1 CDS ilvA NC_003155.4 4110484 4111713 R catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase complement(4110484..4111713) Streptomyces avermitilis MA-4680 1210706 NP_824479.1 CDS SAV_3303 NC_003155.4 4111884 4112384 D MarR family transcriptional regulator 4111884..4112384 Streptomyces avermitilis MA-4680 1214383 NP_824480.1 CDS sig59 NC_003155.4 4112753 4113253 D ECF subfamily RNA polymerase sigma factor 4112753..4113253 Streptomyces avermitilis MA-4680 1214384 NP_824481.1 CDS metB NC_003155.4 4113526 4114680 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(4113526..4114680) Streptomyces avermitilis MA-4680 1210707 NP_824482.1 CDS SAV_3306 NC_003155.4 4114899 4116017 D hypothetical protein 4114899..4116017 Streptomyces avermitilis MA-4680 1214385 NP_824483.1 CDS SAV_3307 NC_003155.4 4116264 4116776 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4116264..4116776) Streptomyces avermitilis MA-4680 1214386 NP_824484.1 CDS SAV_3308 NC_003155.4 4117077 4117670 D hypothetical protein 4117077..4117670 Streptomyces avermitilis MA-4680 1214387 NP_824485.1 CDS savR NC_003155.4 4117931 4119991 R Mrr restriction system protein complement(4117931..4119991) Streptomyces avermitilis MA-4680 1214388 NP_824486.1 CDS SAV_3310 NC_003155.4 4121085 4121843 D hypothetical protein 4121085..4121843 Streptomyces avermitilis MA-4680 1214389 NP_824487.1 CDS SAV_3311 NC_003155.4 4122010 4123197 R hypothetical protein complement(4122010..4123197) Streptomyces avermitilis MA-4680 1214390 NP_824488.1 CDS SAV_3312 NC_003155.4 4123347 4124225 D PF03575: Peptidase family S51; hypothetical protein 4123347..4124225 Streptomyces avermitilis MA-4680 1214391 NP_824489.1 CDS SAV_3313 NC_003155.4 4124262 4125098 D PF01032: FecCD transport family; iron-siderophore uptake system transmembrane component 4124262..4125098 Streptomyces avermitilis MA-4680 1214392 NP_824490.1 CDS adhA4 NC_003155.4 4125234 4126277 R NADP-dependent alcohol dehydrogenase complement(4125234..4126277) Streptomyces avermitilis MA-4680 1210708 NP_824491.1 CDS SAV_3315 NC_003155.4 4126449 4127360 D DNA-binding protein 4126449..4127360 Streptomyces avermitilis MA-4680 1214393 NP_824492.1 CDS SAV_3316 NC_003155.4 4127452 4128234 R PF01152: Bacterial-like globin; hypothetical protein complement(4127452..4128234) Streptomyces avermitilis MA-4680 1214394 NP_824493.1 CDS SAV_3317 NC_003155.4 4128332 4128601 R hypothetical protein complement(4128332..4128601) Streptomyces avermitilis MA-4680 1214395 NP_824494.1 CDS sig24 NC_003155.4 4129027 4129605 R ECF subfamily RNA polymerase sigma factor complement(4129027..4129605) Streptomyces avermitilis MA-4680 1210709 NP_824495.1 CDS SAV_3319 NC_003155.4 4129829 4133248 R PF00082: Subtilase family; subtilisin-like protease complement(4129829..4133248) Streptomyces avermitilis MA-4680 1214396 NP_824496.1 CDS SAV_3320 NC_003155.4 4133353 4134036 R ABC transporter ATP-binding protein complement(4133353..4134036) Streptomyces avermitilis MA-4680 1214397 NP_824497.1 CDS SAV_3321 NC_003155.4 4134070 4135542 R PF02687: Predicted permease; integral membrane protein complement(4134070..4135542) Streptomyces avermitilis MA-4680 1214398 NP_824498.1 CDS SAV_3322 NC_003155.4 4135745 4136995 R PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein complement(4135745..4136995) Streptomyces avermitilis MA-4680 1214399 NP_824499.1 CDS SAV_3323 NC_003155.4 4137239 4137532 R hypothetical protein complement(4137239..4137532) Streptomyces avermitilis MA-4680 1214400 NP_824500.1 CDS SAV_3324 NC_003155.4 4137694 4138038 D hypothetical protein 4137694..4138038 Streptomyces avermitilis MA-4680 1214401 NP_824501.1 CDS hutH NC_003155.4 4138180 4139724 R catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase complement(4138180..4139724) Streptomyces avermitilis MA-4680 1210710 NP_824502.1 CDS SAV_3326 NC_003155.4 4139856 4140947 R PF00990: GGDEF domain; protein complement(4139856..4140947) Streptomyces avermitilis MA-4680 1214402 NP_824503.1 CDS echA9 NC_003155.4 4141081 4141893 R enoyl-CoA hydratase complement(4141081..4141893) Streptomyces avermitilis MA-4680 1210711 NP_824504.1 CDS SAV_3328 NC_003155.4 4142438 4142968 D hypothetical protein 4142438..4142968 Streptomyces avermitilis MA-4680 1214403 NP_824505.1 CDS cyaA NC_003155.4 4143008 4144225 R PF00211: Adenylate and Guanylate cyclase catalytic domain; adenylate cyclase complement(4143008..4144225) Streptomyces avermitilis MA-4680 1210712 NP_824506.1 CDS birA NC_003155.4 4144421 4145296 R biotin apo-protein ligase complement(4144421..4145296) Streptomyces avermitilis MA-4680 1210713 NP_824507.1 CDS pccB NC_003155.4 4145450 4147048 D propionyl-CoA carboxylase, beta subunit 4145450..4147048 Streptomyces avermitilis MA-4680 1210714 NP_824508.1 CDS SAV_3332 NC_003155.4 4147065 4147274 D hypothetical protein 4147065..4147274 Streptomyces avermitilis MA-4680 1214404 NP_824509.1 CDS SAV_3333 NC_003155.4 4147295 4148542 R PF00657: GDSL-like Lipase/Acylhydrolase; protein complement(4147295..4148542) Streptomyces avermitilis MA-4680 1214405 NP_824510.1 CDS SAV_3334 NC_003155.4 4148634 4148780 D hypothetical protein 4148634..4148780 Streptomyces avermitilis MA-4680 1214406 NP_824511.1 CDS SAV_3335 NC_003155.4 4148785 4149405 D PF02545: Maf-like protein; septum formation protein 4148785..4149405 Streptomyces avermitilis MA-4680 1214407 NP_824512.1 CDS SAV_3336 NC_003155.4 4149406 4149930 R integral membrane protein complement(4149406..4149930) Streptomyces avermitilis MA-4680 1214408 NP_824513.1 CDS accA3 NC_003155.4 4150323 4152095 D biotin carboxylase and biotin carboxyl carrier protein; acyl-CoA carboxylase alpha subunit 4150323..4152095 Streptomyces avermitilis MA-4680 1210715 NP_824514.1 CDS SAV_3338 NC_003155.4 4152374 4153447 R PF00196: Bacterial regulatory proteins, luxR family; hypothetical protein complement(4152374..4153447) Streptomyces avermitilis MA-4680 1214409 NP_824515.1 CDS SAV_3339 NC_003155.4 4153735 4154661 R DeoR family transcriptional regulator complement(4153735..4154661) Streptomyces avermitilis MA-4680 1214410 NP_824516.1 CDS SAV_3340 NC_003155.4 4154875 4156302 R catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase complement(4154875..4156302) Streptomyces avermitilis MA-4680 1214411 NP_824517.1 CDS SAV_3341 NC_003155.4 4156420 4156857 D hypothetical protein 4156420..4156857 Streptomyces avermitilis MA-4680 1214412 NP_824518.1 CDS deoD NC_003155.4 4157159 4157983 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 4157159..4157983 Streptomyces avermitilis MA-4680 1210716 NP_824519.1 CDS pmmB NC_003155.4 4158185 4159816 D phosphomannomutase 4158185..4159816 Streptomyces avermitilis MA-4680 1210717 NP_824520.1 CDS SAV_3344 NC_003155.4 4159993 4161672 R PF01545: Cation efflux family; hypothetical protein complement(4159993..4161672) Streptomyces avermitilis MA-4680 1214413 NP_824521.1 CDS SAV_3345 NC_003155.4 4161915 4162571 R integral membrane protein complement(4161915..4162571) Streptomyces avermitilis MA-4680 1214414 NP_824522.1 CDS deoC NC_003155.4 4162733 4163722 D deoxyribose-phosphate aldolase 4162733..4163722 Streptomyces avermitilis MA-4680 1210718 NP_824523.1 CDS SAV_3347 NC_003155.4 4163729 4165165 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 4163729..4165165 Streptomyces avermitilis MA-4680 1214415 NP_824524.1 CDS SAV_3348 NC_003155.4 4165158 4166066 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 4165158..4166066 Streptomyces avermitilis MA-4680 1214416 NP_824525.1 CDS SAV_3349 NC_003155.4 4166279 4166674 R hypothetical protein complement(4166279..4166674) Streptomyces avermitilis MA-4680 1214417 NP_824526.1 CDS SAV_3350 NC_003155.4 4166728 4167432 D ATP-binding protein 4166728..4167432 Streptomyces avermitilis MA-4680 1214418 NP_824527.1 CDS sig25 NC_003155.4 4167629 4168249 R ECF subfamily RNA polymerase sigma factor complement(4167629..4168249) Streptomyces avermitilis MA-4680 1210719 NP_824528.1 CDS smrA NC_003155.4 4168730 4169407 D PF00072: Response regulator receiver domain; two-component system response regulator 4168730..4169407 Streptomyces avermitilis MA-4680 1210720 NP_824529.1 CDS smrB NC_003155.4 4169404 4170969 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two-component system sensor kinase 4169404..4170969 Streptomyces avermitilis MA-4680 1210721 NP_824530.1 CDS SAV_3354 NC_003155.4 4171002 4171631 D lipoprotein 4171002..4171631 Streptomyces avermitilis MA-4680 1214419 NP_824531.1 CDS SAV_3355 NC_003155.4 4171759 4172310 D PF04892: VanZ like family; integral membrane protein 4171759..4172310 Streptomyces avermitilis MA-4680 1214420 NP_824532.1 CDS SAV_3356 NC_003155.4 4172399 4172602 D PF04024: PspC domain; hypothetical protein 4172399..4172602 Streptomyces avermitilis MA-4680 1214421 NP_824533.1 CDS SAV_3357 NC_003155.4 4172712 4173044 R protein complement(4172712..4173044) Streptomyces avermitilis MA-4680 1214422 NP_824534.1 CDS add3 NC_003155.4 4173175 4174389 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(4173175..4174389) Streptomyces avermitilis MA-4680 1210722 NP_824535.1 CDS SAV_3359 NC_003155.4 4174443 4175207 D PF00326: Prolyl oligopeptidase family; hypothetical protein 4174443..4175207 Streptomyces avermitilis MA-4680 1214423 NP_824536.1 CDS SAV_3360 NC_003155.4 4175295 4176248 R LysR family transcriptional regulator complement(4175295..4176248) Streptomyces avermitilis MA-4680 1214424 NP_824537.1 CDS SAV_3361 NC_003155.4 4176312 4177604 D PF07690: Major Facilitator Superfamily; transport integral membrane protein 4176312..4177604 Streptomyces avermitilis MA-4680 1214425 NP_824538.1 CDS dnaN2 NC_003155.4 4177745 4178875 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4177745..4178875 Streptomyces avermitilis MA-4680 1210723 NP_824539.1 CDS sig26 NC_003155.4 4179014 4180018 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 4179014..4180018 Streptomyces avermitilis MA-4680 1210724 NP_824540.1 CDS SAV_3364 NC_003155.4 4179911 4180297 R hypothetical protein complement(4179911..4180297) Streptomyces avermitilis MA-4680 1214426 NP_824541.1 CDS deoA NC_003155.4 4180427 4181710 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(4180427..4181710) Streptomyces avermitilis MA-4680 1210725 NP_824542.1 CDS cdd2 NC_003155.4 4181779 4182195 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(4181779..4182195) Streptomyces avermitilis MA-4680 1210726 NP_824543.1 CDS SAV_3367 NC_003155.4 4182192 4183445 R sugar ABC transporter permease complement(4182192..4183445) Streptomyces avermitilis MA-4680 1214427 NP_824544.1 CDS SAV_3368 NC_003155.4 4183451 4184581 R PF02653: Branched-chain amino acid transport system / permease component; sugar ABC transporter permease complement(4183451..4184581) Streptomyces avermitilis MA-4680 1214428 NP_824545.1 CDS SAV_3369 NC_003155.4 4184578 4186161 R sugar ABC transporter ATP-binding protein complement(4184578..4186161) Streptomyces avermitilis MA-4680 1214429 NP_824546.1 CDS SAV_3370 NC_003155.4 4186443 4187498 R PF02608: Basic membrane protein; lipoprotein complement(4186443..4187498) Streptomyces avermitilis MA-4680 1214430 NP_824547.1 CDS SAV_7581 NC_003155.4 4187781 4188854 R simple sugar transport system substrate-binding protein complement(4187781..4188854) Streptomyces avermitilis MA-4680 1214431 NP_824548.1 CDS SAV_3371 NC_003155.4 4189087 4190340 R PF01546: Peptidase family M20/M25/M40; metal-dependent amidase/aminoacylase/carboxypeptidase complement(4189087..4190340) Streptomyces avermitilis MA-4680 1210727 NP_824549.1 CDS SAV_3372 NC_003155.4 4190713 4191786 R hypothetical protein complement(4190713..4191786) Streptomyces avermitilis MA-4680 1214432 NP_824550.1 CDS SAV_3373 NC_003155.4 4191813 4192748 R N-acetylneuraminic acid (Neu5Ac) synthase complement(4191813..4192748) Streptomyces avermitilis MA-4680 1214433 NP_824551.1 CDS SAV_3374 NC_003155.4 4192762 4194060 R transferase complement(4192762..4194060) Streptomyces avermitilis MA-4680 1214434 NP_824552.1 CDS SAV_3375 NC_003155.4 4194093 4195448 R hypothetical protein complement(4194093..4195448) Streptomyces avermitilis MA-4680 1214435 NP_824553.1 CDS SAV_3376 NC_003155.4 4195647 4196627 D transferase 4195647..4196627 Streptomyces avermitilis MA-4680 1214436 NP_824554.1 CDS SAV_3377 NC_003155.4 4196624 4197958 D hypothetical protein 4196624..4197958 Streptomyces avermitilis MA-4680 1214437 NP_824555.1 CDS SAV_3378 NC_003155.4 4197991 4199139 D PF01757: Acyltransferase family; hypothetical protein 4197991..4199139 Streptomyces avermitilis MA-4680 1214438 NP_824556.1 CDS SAV_3379 NC_003155.4 4199236 4199886 R TetR family transcriptional regulator complement(4199236..4199886) Streptomyces avermitilis MA-4680 1214439 NP_824557.1 CDS SAV_3380 NC_003155.4 4199925 4201361 D PF01360: Monooxygenase; hypothetical protein 4199925..4201361 Streptomyces avermitilis MA-4680 1214440 NP_824558.1 CDS SAV_3381 NC_003155.4 4201358 4202011 R PF01810: LysE type translocator; leucine export protein LeuE complement(4201358..4202011) Streptomyces avermitilis MA-4680 1214441 NP_824559.1 CDS mcmA2 NC_003155.4 4202111 4203691 R methylmalonyl-CoA mutase subunit alpha complement(4202111..4203691) Streptomyces avermitilis MA-4680 1210728 NP_824560.1 CDS SAV_3383 NC_003155.4 4203959 4204816 D PF01471: Putative peptidoglycan binding domain; lipoprotein 4203959..4204816 Streptomyces avermitilis MA-4680 1214442 NP_824561.1 CDS SAV_3384 NC_003155.4 4205272 4206369 R hypothetical protein complement(4205272..4206369) Streptomyces avermitilis MA-4680 1214443 NP_824562.1 CDS sig27 NC_003155.4 4206366 4207079 R ECF subfamily RNA polymerase sigma factor complement(4206366..4207079) Streptomyces avermitilis MA-4680 1210729 NP_824563.1 CDS SAV_3386 NC_003155.4 4207446 4208129 R hypothetical protein complement(4207446..4208129) Streptomyces avermitilis MA-4680 1214444 NP_824564.1 CDS sig28 NC_003155.4 4208154 4208843 R ECF subfamily RNA polymerase sigma factor complement(4208154..4208843) Streptomyces avermitilis MA-4680 1210730 NP_824565.1 CDS SAV_3388 NC_003155.4 4209033 4211747 D PF01839: FG-GAP repeat; hypothetical protein 4209033..4211747 Streptomyces avermitilis MA-4680 1214445 NP_824566.1 CDS SAV_3389 NC_003155.4 4211824 4212282 R hypothetical protein complement(4211824..4212282) Streptomyces avermitilis MA-4680 1214446 NP_824567.1 CDS SAV_3390 NC_003155.4 4212357 4212917 R hypothetical protein complement(4212357..4212917) Streptomyces avermitilis MA-4680 1214447 NP_824568.1 CDS SAV_3391 NC_003155.4 4213002 4213529 R hypothetical protein complement(4213002..4213529) Streptomyces avermitilis MA-4680 1214448 NP_824569.1 CDS SAV_3392 NC_003155.4 4213630 4214691 R hypothetical protein complement(4213630..4214691) Streptomyces avermitilis MA-4680 1214449 NP_824570.1 CDS nagZ2 NC_003155.4 4214726 4216363 R beta-N-acetylglucosaminidase complement(4214726..4216363) Streptomyces avermitilis MA-4680 1214450 NP_824571.1 CDS SAV_3394 NC_003155.4 4216717 4217205 D putative OHCU decarboxylase 4216717..4217205 Streptomyces avermitilis MA-4680 1214451 NP_824572.1 CDS sdhC NC_003155.4 4217404 4217784 D succinate dehydrogenase cytochrome b-556 subunit 4217404..4217784 Streptomyces avermitilis MA-4680 1210731 NP_824573.1 CDS sdhD NC_003155.4 4217790 4218272 D succinate dehydrogenase hydrophobic membrane anchor protein 4217790..4218272 Streptomyces avermitilis MA-4680 1210732 NP_824574.1 CDS sdhA NC_003155.4 4218295 4220049 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 4218295..4220049 Streptomyces avermitilis MA-4680 1210733 NP_824575.1 CDS sdhB NC_003155.4 4220049 4220822 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 4220049..4220822 Streptomyces avermitilis MA-4680 1210734 NP_824576.1 CDS SAV_3399 NC_003155.4 4220893 4221156 R PF05154: TM2 domain; hypothetical protein complement(4220893..4221156) Streptomyces avermitilis MA-4680 1214452 NP_824577.1 CDS SAV_3400 NC_003155.4 4221425 4221835 R hypothetical protein complement(4221425..4221835) Streptomyces avermitilis MA-4680 1214453 NP_824578.1 CDS SAV_3401 NC_003155.4 4221828 4222328 R PF05154: TM2 domain; hypothetical protein complement(4221828..4222328) Streptomyces avermitilis MA-4680 1214454 NP_824579.1 CDS SAV_3402 NC_003155.4 4222417 4224888 R hypothetical protein complement(4222417..4224888) Streptomyces avermitilis MA-4680 1214455 NP_824580.1 CDS SAV_3403 NC_003155.4 4224891 4225385 R hypothetical protein complement(4224891..4225385) Streptomyces avermitilis MA-4680 1214456 NP_824581.1 CDS SAV_3404 NC_003155.4 4225432 4225845 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 4225432..4225845 Streptomyces avermitilis MA-4680 1214457 NP_824582.1 CDS SAV_3405 NC_003155.4 4226006 4226413 D hypothetical protein 4226006..4226413 Streptomyces avermitilis MA-4680 1214458 NP_824583.1 CDS SAV_3406 NC_003155.4 4226410 4226928 D PF04134: Protein of unknown function, DUF393; hypothetical protein 4226410..4226928 Streptomyces avermitilis MA-4680 1214459 NP_824584.1 CDS SAV_3407 NC_003155.4 4226939 4227736 D TetR family transcriptional regulator 4226939..4227736 Streptomyces avermitilis MA-4680 1214460 NP_824585.1 CDS SAV_3408 NC_003155.4 4227749 4230178 R PF03176: MMPL family; integral membrane export protein complement(4227749..4230178) Streptomyces avermitilis MA-4680 1214461 NP_824586.1 CDS SAV_3409 NC_003155.4 4230348 4231079 D two-component system response regulator 4230348..4231079 Streptomyces avermitilis MA-4680 1214462 NP_824587.1 CDS SAV_3410 NC_003155.4 4231076 4232521 D two-component system sensor kinase 4231076..4232521 Streptomyces avermitilis MA-4680 1214463 NP_824588.1 CDS SAV_3411 NC_003155.4 4232582 4233871 R PF00149: Calcineurin-like phosphoesterase; hypothetical protein complement(4232582..4233871) Streptomyces avermitilis MA-4680 1214464 NP_824589.1 CDS SAV_3412 NC_003155.4 4233904 4234146 R integral membrane protein complement(4233904..4234146) Streptomyces avermitilis MA-4680 1214465 NP_824590.1 CDS dacB NC_003155.4 4234250 4235593 D PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 4234250..4235593 Streptomyces avermitilis MA-4680 1210735 NP_824591.1 CDS SAV_3414 NC_003155.4 4235541 4236575 R PF03631: Ribonuclease BN-like family; ribonuclease BN family membrane protein complement(4235541..4236575) Streptomyces avermitilis MA-4680 1214466 NP_824592.1 CDS SAV_3415 NC_003155.4 4236669 4237433 D PF00106: short chain dehydrogenase; dehydrogenase 4236669..4237433 Streptomyces avermitilis MA-4680 1214467 NP_824593.1 CDS SAV_3416 NC_003155.4 4237848 4238429 R protein complement(4237848..4238429) Streptomyces avermitilis MA-4680 1214468 NP_824594.1 CDS trpS1 NC_003155.4 4238566 4239579 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(4238566..4239579) Streptomyces avermitilis MA-4680 1210736 NP_824595.1 CDS SAV_3418 NC_003155.4 4239779 4240402 D hypothetical protein 4239779..4240402 Streptomyces avermitilis MA-4680 1214469 NP_824596.1 CDS glyA NC_003155.4 4240427 4241875 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(4240427..4241875) Streptomyces avermitilis MA-4680 1210737 NP_824597.1 CDS rocD1 NC_003155.4 4242088 4243341 D ornithine aminotransferase 4242088..4243341 Streptomyces avermitilis MA-4680 1210738 NP_824598.1 CDS SAV_3421 NC_003155.4 4243356 4244543 R glutathionylspermidine synthase complement(4243356..4244543) Streptomyces avermitilis MA-4680 1214470 NP_824599.1 CDS SAV_3422 NC_003155.4 4244574 4244936 R hypothetical protein complement(4244574..4244936) Streptomyces avermitilis MA-4680 1214471 NP_824600.1 CDS SAV_3423 NC_003155.4 4245054 4245878 D PF00892: Integral membrane protein DUF6; integral membrane protein 4245054..4245878 Streptomyces avermitilis MA-4680 1214472 NP_824601.1 CDS SAV_3424 NC_003155.4 4245920 4246339 R regulatory protein complement(4245920..4246339) Streptomyces avermitilis MA-4680 1214473 NP_824602.1 CDS SAV_3425 NC_003155.4 4246533 4247384 D DNA-binding protein 4246533..4247384 Streptomyces avermitilis MA-4680 1214474 NP_824603.1 CDS SAV_3426 NC_003155.4 4247394 4247594 D PF04149: Domain of unknown function (DUF397); hypothetical protein 4247394..4247594 Streptomyces avermitilis MA-4680 1214475 NP_824604.1 CDS SAV_3427 NC_003155.4 4247635 4249071 R GntR family transcriptional regulator complement(4247635..4249071) Streptomyces avermitilis MA-4680 1214476 NP_824605.1 CDS SAV_3428 NC_003155.4 4249119 4249640 D PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein 4249119..4249640 Streptomyces avermitilis MA-4680 1214477 NP_824606.1 CDS SAV_3429 NC_003155.4 4249762 4250478 D transferase 4249762..4250478 Streptomyces avermitilis MA-4680 1214478 NP_824607.1 CDS SAV_3430 NC_003155.4 4250525 4251499 R glycine betaine-binding lipoprotein complement(4250525..4251499) Streptomyces avermitilis MA-4680 1214479 NP_824608.1 CDS SAV_3431 NC_003155.4 4251501 4253444 R glycine/betaine ABC transporter permease complement(4251501..4253444) Streptomyces avermitilis MA-4680 1214480 NP_824609.1 CDS SAV_3432 NC_003155.4 4253444 4254613 R glycine/betaine ABC transporter ATP-binding protein complement(4253444..4254613) Streptomyces avermitilis MA-4680 1214481 NP_824610.1 CDS SAV_3433 NC_003155.4 4254610 4256160 R PF00732: GMC oxidoreductase; oxidoreductase complement(4254610..4256160) Streptomyces avermitilis MA-4680 1214482 NP_824611.1 CDS gbsA2 NC_003155.4 4256271 4257800 R glycine betaine aldehyde dehydrogenase complement(4256271..4257800) Streptomyces avermitilis MA-4680 1210739 NP_824612.1 CDS SAV_3435 NC_003155.4 4258097 4259335 R PF04554: Extensin-like region; hypothetical protein complement(4258097..4259335) Streptomyces avermitilis MA-4680 1214483 NP_824613.1 CDS mdh NC_003155.4 4259507 4260496 R catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase complement(4259507..4260496) Streptomyces avermitilis MA-4680 1210740 NP_824614.1 CDS SAV_3437 NC_003155.4 4261015 4262277 R PF01381: Helix-turn-helix; hypothetical protein complement(4261015..4262277) Streptomyces avermitilis MA-4680 1214484 NP_824615.1 CDS SAV_3438 NC_003155.4 4262617 4263129 R hypothetical protein complement(4262617..4263129) Streptomyces avermitilis MA-4680 1214485 NP_824616.1 CDS SAV_3439 NC_003155.4 4263664 4264200 D hypothetical protein 4263664..4264200 Streptomyces avermitilis MA-4680 1214486 NP_824617.1 CDS SAV_3440 NC_003155.4 4264282 4264899 R hypothetical protein complement(4264282..4264899) Streptomyces avermitilis MA-4680 1214487 NP_824618.1 CDS SAV_3441 NC_003155.4 4265174 4265803 R hypothetical protein complement(4265174..4265803) Streptomyces avermitilis MA-4680 1214488 NP_824619.1 CDS folD1 NC_003155.4 4265904 4266758 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(4265904..4266758) Streptomyces avermitilis MA-4680 1210741 NP_824620.1 CDS SAV_3443 NC_003155.4 4267000 4267671 D PF06271: RDD family; hypothetical protein 4267000..4267671 Streptomyces avermitilis MA-4680 1214489 NP_824621.1 CDS purH NC_003155.4 4267834 4269417 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4267834..4269417) Streptomyces avermitilis MA-4680 1210742 NP_824622.1 CDS purN NC_003155.4 4269414 4270043 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(4269414..4270043) Streptomyces avermitilis MA-4680 1210743 NP_824623.1 CDS SAV_3446 NC_003155.4 4270386 4271324 D hypothetical protein 4270386..4271324 Streptomyces avermitilis MA-4680 1214490 NP_824624.1 CDS SAV_3447 NC_003155.4 4271414 4271809 R hypothetical protein complement(4271414..4271809) Streptomyces avermitilis MA-4680 1214491 NP_824625.1 CDS SAV_3448 NC_003155.4 4271816 4272148 R hypothetical protein complement(4271816..4272148) Streptomyces avermitilis MA-4680 1214492 NP_824626.1 CDS SAV_3449 NC_003155.4 4272171 4273145 R integral membrane protein complement(4272171..4273145) Streptomyces avermitilis MA-4680 1214493 NP_824627.1 CDS SAV_3450 NC_003155.4 4273338 4274450 D hypothetical protein 4273338..4274450 Streptomyces avermitilis MA-4680 1214494 NP_824628.1 CDS sucD2 NC_003155.4 4274601 4275485 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(4274601..4275485) Streptomyces avermitilis MA-4680 1210744 NP_824629.1 CDS sucC NC_003155.4 4275507 4276685 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(4275507..4276685) Streptomyces avermitilis MA-4680 1210745 NP_824630.1 CDS SAV_3453 NC_003155.4 4277143 4279029 R threonine-rich protein; hypothetical protein complement(4277143..4279029) Streptomyces avermitilis MA-4680 1214495 NP_824631.1 CDS SAV_3454 NC_003155.4 4279317 4280501 R hypothetical protein complement(4279317..4280501) Streptomyces avermitilis MA-4680 1214496 NP_824632.1 CDS SAV_3455 NC_003155.4 4280661 4281710 R PF05762: VWA domain containing CoxE-like protein; hypothetical protein complement(4280661..4281710) Streptomyces avermitilis MA-4680 1214497 NP_824633.1 CDS SAV_3456 NC_003155.4 4281929 4284355 R hypothetical protein complement(4281929..4284355) Streptomyces avermitilis MA-4680 1214498 NP_824634.1 CDS SAV_3457 NC_003155.4 4284524 4285732 R PF07728: ATPase family associated with various cellular activities (AAA); MoxR-like ATPase complement(4284524..4285732) Streptomyces avermitilis MA-4680 1214499 NP_824635.1 CDS SAV_3458 NC_003155.4 4286007 4287221 D PF04434: SWIM zinc finger; hypothetical protein 4286007..4287221 Streptomyces avermitilis MA-4680 1214500 NP_824636.1 CDS SAV_3459 NC_003155.4 4287278 4288918 D hypothetical protein 4287278..4288918 Streptomyces avermitilis MA-4680 1214501 NP_824637.1 CDS icmB NC_003155.4 4289212 4289628 R isobutyryl-CoA mutase subunit B complement(4289212..4289628) Streptomyces avermitilis MA-4680 1210746 NP_824638.1 CDS SAV_3461 NC_003155.4 4290165 4291025 D lipase 4290165..4291025 Streptomyces avermitilis MA-4680 1214502 NP_824639.1 CDS SAV_3462 NC_003155.4 4291312 4292910 D PF01551: Peptidase family M23; peptidase 4291312..4292910 Streptomyces avermitilis MA-4680 1214503 NP_824640.1 CDS uvrD1 NC_003155.4 4293057 4295642 R ATP-dependent DNA helicase complement(4293057..4295642) Streptomyces avermitilis MA-4680 1210747 NP_824641.1 CDS SAV_3464 NC_003155.4 4296320 4297516 D Seems to have no N-terminal signal sequence; NLP/P60-family protein 4296320..4297516 Streptomyces avermitilis MA-4680 1214504 NP_824642.1 CDS SAV_3465 NC_003155.4 4297586 4298611 D PF03595: C4-dicarboxylate transporter/malic acid transport protein; integral membrane protein 4297586..4298611 Streptomyces avermitilis MA-4680 1214505 NP_824643.1 CDS SAV_3466 NC_003155.4 4298589 4298942 R integral membrane protein complement(4298589..4298942) Streptomyces avermitilis MA-4680 1214506 NP_824644.1 CDS SAV_3467 NC_003155.4 4299352 4300428 D NLP/P60-family protein 4299352..4300428 Streptomyces avermitilis MA-4680 1214507 NP_824645.1 CDS SAV_3468 NC_003155.4 4300610 4301392 D hypothetical protein 4300610..4301392 Streptomyces avermitilis MA-4680 1214508 NP_824646.1 CDS SAV_3469 NC_003155.4 4301418 4301591 R hypothetical protein complement(4301418..4301591) Streptomyces avermitilis MA-4680 1214509 NP_824647.1 CDS SAV_3470 NC_003155.4 4301738 4302469 R two-component system response regulator complement(4301738..4302469) Streptomyces avermitilis MA-4680 1214510 NP_824648.1 CDS SAV_3471 NC_003155.4 4302466 4303755 R two-component system sensor kinase complement(4302466..4303755) Streptomyces avermitilis MA-4680 1214511 NP_824649.1 CDS SAV_3472 NC_003155.4 4303934 4305370 D PF04024: PspC domain; hypothetical protein 4303934..4305370 Streptomyces avermitilis MA-4680 1214512 NP_824650.1 CDS SAV_3473 NC_003155.4 4305357 4305617 D hypothetical protein 4305357..4305617 Streptomyces avermitilis MA-4680 1214513 NP_824651.1 CDS SAV_3474 NC_003155.4 4305813 4306331 R PF07681: DoxX; hypothetical protein complement(4305813..4306331) Streptomyces avermitilis MA-4680 1214514 NP_824652.1 CDS SAV_3475 NC_003155.4 4306512 4307801 R hypothetical protein complement(4306512..4307801) Streptomyces avermitilis MA-4680 1214515 NP_824653.1 CDS SAV_3476 NC_003155.4 4308124 4309002 D hypothetical protein 4308124..4309002 Streptomyces avermitilis MA-4680 1214516 NP_824654.1 CDS fucA1 NC_003155.4 4309008 4309829 R hypothetical protein complement(4309008..4309829) Streptomyces avermitilis MA-4680 1214517 NP_824655.1 CDS SAV_3478 NC_003155.4 4310058 4310534 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 4310058..4310534 Streptomyces avermitilis MA-4680 1214518 NP_824656.1 CDS guaA NC_003155.4 4310567 4312144 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(4310567..4312144) Streptomyces avermitilis MA-4680 1210748 NP_824657.1 CDS SAV_3480 NC_003155.4 4312291 4313571 R two-component system sensor kinase complement(4312291..4313571) Streptomyces avermitilis MA-4680 1214519 NP_824658.1 CDS SAV_3481 NC_003155.4 4313612 4314289 R two-component system response regulator complement(4313612..4314289) Streptomyces avermitilis MA-4680 1214520 NP_824659.1 CDS SAV_3482 NC_003155.4 4314888 4316384 D PF00854: POT family; di-tripeptide transporter 4314888..4316384 Streptomyces avermitilis MA-4680 1214521 NP_824660.1 CDS SAV_3483 NC_003155.4 4316481 4317110 R phosphoglycerate mutase complement(4316481..4317110) Streptomyces avermitilis MA-4680 1214522 NP_824661.1 CDS SAV_3484 NC_003155.4 4317304 4318536 R hypothetical protein complement(4317304..4318536) Streptomyces avermitilis MA-4680 1214523 NP_824662.1 CDS SAV_3485 NC_003155.4 4318608 4319714 R hypothetical protein complement(4318608..4319714) Streptomyces avermitilis MA-4680 1214524 NP_824663.1 CDS SAV_3486 NC_003155.4 4319729 4320781 R hypothetical protein complement(4319729..4320781) Streptomyces avermitilis MA-4680 1214525 NP_824664.1 CDS SAV_3487 NC_003155.4 4320873 4321568 R PF00746: Gram positive anchor; hypothetical protein complement(4320873..4321568) Streptomyces avermitilis MA-4680 1214526 NP_824665.1 CDS SAV_3488 NC_003155.4 4321740 4322399 R similar to sigma factor regulator prsI; regulator protein complement(4321740..4322399) Streptomyces avermitilis MA-4680 1214527 NP_824666.1 CDS SAV_3489 NC_003155.4 4322655 4323023 R PF01740: STAS domain; anti-sigma factor antagonist complement(4322655..4323023) Streptomyces avermitilis MA-4680 1214528 NP_824667.1 CDS sig29 NC_003155.4 4323274 4324194 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 4323274..4324194 Streptomyces avermitilis MA-4680 1210749 NP_824668.1 CDS SAV_3491 NC_003155.4 4324523 4326172 D PF00652: QXW lectin repeat; hypothetical protein 4324523..4326172 Streptomyces avermitilis MA-4680 1214529 NP_824669.1 CDS SAV_3492 NC_003155.4 4326262 4326837 D hypothetical protein 4326262..4326837 Streptomyces avermitilis MA-4680 1214530 NP_824670.1 CDS hutI NC_003155.4 4326856 4328100 R catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase complement(4326856..4328100) Streptomyces avermitilis MA-4680 1210750 NP_824671.1 CDS SAV_3494 NC_003155.4 4328136 4329470 R catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase complement(4328136..4329470) Streptomyces avermitilis MA-4680 1214531 NP_824672.1 CDS SAV_3495 NC_003155.4 4329467 4330708 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(4329467..4330708) Streptomyces avermitilis MA-4680 1214532 NP_824673.1 CDS hutU NC_003155.4 4330705 4332369 R catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase complement(4330705..4332369) Streptomyces avermitilis MA-4680 1210751 NP_824674.1 CDS SAV_3497 NC_003155.4 4332475 4333932 D PF02784: Pyridoxal-dependent decarboxylase, pyridoxal binding domain; lysine/ornithine decarboxylase 4332475..4333932 Streptomyces avermitilis MA-4680 1214533 NP_824675.1 CDS SAV_3498 NC_003155.4 4334240 4334635 D hypothetical protein 4334240..4334635 Streptomyces avermitilis MA-4680 1214534 NP_824676.1 CDS SAV_3499 NC_003155.4 4334632 4335756 D hypothetical protein 4334632..4335756 Streptomyces avermitilis MA-4680 1214535 NP_824677.1 CDS SAV_3500 NC_003155.4 4335795 4336316 D PF03259: Roadblock/LC7 domain; hypothetical protein 4335795..4336316 Streptomyces avermitilis MA-4680 1214536 NP_824678.1 CDS SAV_3501 NC_003155.4 4336331 4336705 D hypothetical protein 4336331..4336705 Streptomyces avermitilis MA-4680 1214537 NP_824679.1 CDS SAV_3502 NC_003155.4 4336713 4337297 R integral membrane protein complement(4336713..4337297) Streptomyces avermitilis MA-4680 1214538 NP_824680.1 CDS SAV_3503 NC_003155.4 4337483 4338343 R transcriptional regulator complement(4337483..4338343) Streptomyces avermitilis MA-4680 1214539 NP_824681.1 CDS hutH2 NC_003155.4 4338340 4339986 R EC:4.3.1.3; histidine ammonia-lyase complement(4338340..4339986) Streptomyces avermitilis MA-4680 1210752 NP_824682.1 CDS SAV_3505 NC_003155.4 4340087 4341157 D ABC transporter ATP-binding protein 4340087..4341157 Streptomyces avermitilis MA-4680 1214540 NP_824683.1 CDS SAV_3506 NC_003155.4 4341154 4341795 D ABC transporter permease 4341154..4341795 Streptomyces avermitilis MA-4680 1214541 NP_824684.1 CDS SAV_3507 NC_003155.4 4341774 4342493 D ABC transporter permease 4341774..4342493 Streptomyces avermitilis MA-4680 1214542 NP_824685.1 CDS SAV_3508 NC_003155.4 4342514 4343452 D ABC transporter substrate-binding protein 4342514..4343452 Streptomyces avermitilis MA-4680 1214543 NP_824686.1 CDS SAV_3509 NC_003155.4 4343554 4343979 D hypothetical protein 4343554..4343979 Streptomyces avermitilis MA-4680 1214544 NP_824687.1 CDS cysM1 NC_003155.4 4344378 4345772 R cystathionine beta-synthase complement(4344378..4345772) Streptomyces avermitilis MA-4680 1210753 NP_824688.1 CDS SAV_3511 NC_003155.4 4345918 4346958 D PF00657: GDSL-like Lipase/Acylhydrolase; protein 4345918..4346958 Streptomyces avermitilis MA-4680 1214545 NP_824689.1 CDS fadA2 NC_003155.4 4347182 4348405 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 4347182..4348405 Streptomyces avermitilis MA-4680 1210754 NP_824690.1 CDS SAV_3513 NC_003155.4 4348715 4349512 D protein 4348715..4349512 Streptomyces avermitilis MA-4680 1214546 NP_824691.1 CDS SAV_3514 NC_003155.4 4349555 4349866 R hypothetical protein complement(4349555..4349866) Streptomyces avermitilis MA-4680 1214547 NP_824692.1 CDS SAV_3515 NC_003155.4 4349971 4350201 D hypothetical protein 4349971..4350201 Streptomyces avermitilis MA-4680 1214548 NP_824693.1 CDS SAV_3516 NC_003155.4 4350300 4351181 R PF06539: Protein of unknown function (DUF1112); integral membrane protein complement(4350300..4351181) Streptomyces avermitilis MA-4680 1214549 NP_824694.1 CDS pobA NC_003155.4 4351218 4352609 R catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase complement(4351218..4352609) Streptomyces avermitilis MA-4680 1210755 NP_824695.1 CDS SAV_3518 NC_003155.4 4352756 4353613 R PF01040: UbiA prenyltransferase family; hypothetical protein complement(4352756..4353613) Streptomyces avermitilis MA-4680 1214550 NP_824696.1 CDS cyp15 NC_003155.4 4353631 4355043 R CYP107V1, pobA is located at downstream; cytochrome P450 hydroxylase complement(4353631..4355043) Streptomyces avermitilis MA-4680 1210756 NP_824697.1 CDS SAV_3520 NC_003155.4 4355040 4355435 R hypothetical protein complement(4355040..4355435) Streptomyces avermitilis MA-4680 1214551 NP_824698.1 CDS SAV_3521 NC_003155.4 4355459 4356544 R 3-oxoacyl-ACP synthase III complement(4355459..4356544) Streptomyces avermitilis MA-4680 1214552 NP_824699.1 CDS ppsA NC_003155.4 4356548 4359637 R phosphoenolpyruvate synthase complement(4356548..4359637) Streptomyces avermitilis MA-4680 1210757 NP_824700.1 CDS SAV_3523 NC_003155.4 4359641 4360282 R PF04140: Isoprenylcysteine carboxyl methyltransferase (ICMT) family; hypothetical protein complement(4359641..4360282) Streptomyces avermitilis MA-4680 1214553 NP_824701.1 CDS SAV_3524 NC_003155.4 4360279 4361172 R hypothetical protein complement(4360279..4361172) Streptomyces avermitilis MA-4680 1214554 NP_824702.1 CDS SAV_3525 NC_003155.4 4361587 4362429 D hypothetical protein 4361587..4362429 Streptomyces avermitilis MA-4680 1214555 NP_824703.1 CDS SAV_3526 NC_003155.4 4363118 4363888 D ABC transporter ATP-binding protein 4363118..4363888 Streptomyces avermitilis MA-4680 1214556 NP_824704.1 CDS SAV_3527 NC_003155.4 4363962 4366490 D ABC transporter permease 4363962..4366490 Streptomyces avermitilis MA-4680 1214557 NP_824705.1 CDS cfa NC_003155.4 4366558 4367847 R cyclopropane fatty acid synthase complement(4366558..4367847) Streptomyces avermitilis MA-4680 1210759 NP_824706.1 CDS ndh2 NC_003155.4 4368052 4369359 R PF00070: Pyridine nucleotide-disulphide oxidoreductase; NADH dehydrogenase complement(4368052..4369359) Streptomyces avermitilis MA-4680 1214558 NP_824707.1 CDS ppx1 NC_003155.4 4370029 4370970 R PF02541: Ppx/GppA phosphatase family; exopolyphosphatase complement(4370029..4370970) Streptomyces avermitilis MA-4680 1214559 NP_824708.1 CDS SAV_3531 NC_003155.4 4371105 4371629 R PF04417: Protein of unknown function (DUF501); hypothetical protein complement(4371105..4371629) Streptomyces avermitilis MA-4680 1214560 NP_824709.1 CDS SAV_3532 NC_003155.4 4371658 4372152 R PF04977: Septum formation initiator; hypothetical protein complement(4371658..4372152) Streptomyces avermitilis MA-4680 1214561 NP_824710.1 CDS eno NC_003155.4 4372251 4373537 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(4372251..4373537) Streptomyces avermitilis MA-4680 1210760 NP_824711.1 CDS SAV_3534 NC_003155.4 4373879 4374562 R PF06737: Transglycosylase-like domain; protein complement(4373879..4374562) Streptomyces avermitilis MA-4680 1214562 NP_824712.1 CDS SAV_3535 NC_003155.4 4374923 4375882 R PF06737: Transglycosylase-like domain; protein complement(4374923..4375882) Streptomyces avermitilis MA-4680 1214563 NP_824713.1 CDS SAV_3536 NC_003155.4 4376290 4377663 D CYP107U2; cytochrome P450 4376290..4377663 Streptomyces avermitilis MA-4680 1210761 NP_824714.1 CDS SAV_3537 NC_003155.4 4377718 4378752 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(4377718..4378752) Streptomyces avermitilis MA-4680 1214564 NP_824715.1 CDS SAV_3538 NC_003155.4 4378947 4379606 R lipoprotein complement(4378947..4379606) Streptomyces avermitilis MA-4680 1214565 NP_824716.1 CDS SAV_3539 NC_003155.4 4379753 4380481 R hypothetical protein complement(4379753..4380481) Streptomyces avermitilis MA-4680 1214566 NP_824717.1 CDS pkn6 NC_003155.4 4380736 4382199 R serine/threonine protein kinase complement(4380736..4382199) Streptomyces avermitilis MA-4680 1210762 NP_824718.1 CDS SAV_3541 NC_003155.4 4382265 4382855 R integral membrane protein complement(4382265..4382855) Streptomyces avermitilis MA-4680 1214567 NP_824719.1 CDS savM1 NC_003155.4 4383011 4385047 R weak homology to hsdM; type II restriction-modification system DNA adenine-specific methylase complement(4383011..4385047) Streptomyces avermitilis MA-4680 1214568 NP_824720.1 CDS SAV_3543 NC_003155.4 4385750 4386499 D lipoprotein 4385750..4386499 Streptomyces avermitilis MA-4680 1214569 NP_824721.1 CDS SAV_3544 NC_003155.4 4386709 4387428 R lipoprotein complement(4386709..4387428) Streptomyces avermitilis MA-4680 1214570 NP_824722.1 CDS SAV_3545 NC_003155.4 4387621 4388547 R hypothetical protein complement(4387621..4388547) Streptomyces avermitilis MA-4680 1214571 NP_824723.1 CDS SAV_3546 NC_003155.4 4388666 4389268 D TetR family transcriptional regulator 4388666..4389268 Streptomyces avermitilis MA-4680 1214572 NP_824724.1 CDS SAV_3547 NC_003155.4 4389314 4390057 D ketoreductase 4389314..4390057 Streptomyces avermitilis MA-4680 1214573 NP_824725.1 CDS SAV_3548 NC_003155.4 4390175 4390561 R MerR family transcriptional regulator complement(4390175..4390561) Streptomyces avermitilis MA-4680 1214574 NP_824726.1 CDS mfd NC_003155.4 4390621 4394151 R transcriptional-repair coupling factor complement(4390621..4394151) Streptomyces avermitilis MA-4680 1210763 NP_824727.1 CDS SAV_3550 NC_003155.4 4394409 4396976 R ABC transporter permease complement(4394409..4396976) Streptomyces avermitilis MA-4680 1214575 NP_824728.1 CDS SAV_3551 NC_003155.4 4396973 4397761 R ABC transporter ATP-binding protein complement(4396973..4397761) Streptomyces avermitilis MA-4680 1214576 NP_824729.1 CDS SAV_3552 NC_003155.4 4398149 4399708 D PF07690: Major Facilitator Superfamily; integral membrane transport protein 4398149..4399708 Streptomyces avermitilis MA-4680 1214577 NP_824730.1 CDS SAV_3553 NC_003155.4 4400034 4400513 D PF04341: Protein of unknown function, DUF485; hypothetical protein 4400034..4400513 Streptomyces avermitilis MA-4680 1214578 NP_824731.1 CDS SAV_3554 NC_003155.4 4400510 4402156 D PF00474: Sodium:solute symporter family; transmembrane transport protein 4400510..4402156 Streptomyces avermitilis MA-4680 1214579 NP_824732.1 CDS SAV_3555 NC_003155.4 4402232 4403131 R cellulose-binding protein complement(4402232..4403131) Streptomyces avermitilis MA-4680 1214580 NP_824733.1 CDS SAV_3556 NC_003155.4 4403425 4406136 R PF01391: Collagen triple helix repeat (20 copies); hypothetical protein complement(4403425..4406136) Streptomyces avermitilis MA-4680 1214581 NP_824734.1 CDS SAV_3557 NC_003155.4 4406510 4407496 R hypothetical protein complement(4406510..4407496) Streptomyces avermitilis MA-4680 1214582 NP_824735.1 CDS SAV_3558 NC_003155.4 4407750 4408250 D hypothetical protein 4407750..4408250 Streptomyces avermitilis MA-4680 1214583 NP_824736.1 CDS SAV_3559 NC_003155.4 4408326 4408820 D hypothetical protein 4408326..4408820 Streptomyces avermitilis MA-4680 1214584 NP_824737.1 CDS SAV_3560 NC_003155.4 4408838 4410157 R two-component system sensor kinase complement(4408838..4410157) Streptomyces avermitilis MA-4680 1214585 NP_824738.1 CDS glmU NC_003155.4 4410718 4412166 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4410718..4412166 Streptomyces avermitilis MA-4680 1210765 NP_824739.1 CDS prsA1 NC_003155.4 4412314 4413288 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 4412314..4413288 Streptomyces avermitilis MA-4680 1210766 NP_824740.1 CDS rplY NC_003155.4 4413467 4414060 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 4413467..4414060 Streptomyces avermitilis MA-4680 1210767 NP_824741.1 CDS pth NC_003155.4 4414139 4414750 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4414139..4414750 Streptomyces avermitilis MA-4680 1210768 NP_824742.1 CDS SAV_3565 NC_003155.4 4414835 4415347 D hypothetical protein 4414835..4415347 Streptomyces avermitilis MA-4680 1214586 NP_824743.1 CDS ppc NC_003155.4 4415436 4418168 R phosphoenolpyruvate carboxylase complement(4415436..4418168) Streptomyces avermitilis MA-4680 1210769 NP_824744.1 CDS desC NC_003155.4 4418467 4419477 D fatty acid desaturase 4418467..4419477 Streptomyces avermitilis MA-4680 1210770 NP_824745.1 CDS SAV_3568 NC_003155.4 4419474 4420151 D TetR family transcriptional regulator 4419474..4420151 Streptomyces avermitilis MA-4680 1214587 NP_824746.1 CDS SAV_3569 NC_003155.4 4420266 4420634 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(4420266..4420634) Streptomyces avermitilis MA-4680 1214588 NP_824747.1 CDS SAV_3570 NC_003155.4 4420634 4421443 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(4420634..4421443) Streptomyces avermitilis MA-4680 1214589 NP_824748.1 CDS SAV_3571 NC_003155.4 4421595 4422092 D MarR family transcriptional regulator 4421595..4422092 Streptomyces avermitilis MA-4680 1214590 NP_824749.1 CDS SAV_3572 NC_003155.4 4422051 4422830 R two-component system response regulator complement(4422051..4422830) Streptomyces avermitilis MA-4680 1214591 NP_824750.1 CDS SAV_3573 NC_003155.4 4423042 4423533 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 4423042..4423533 Streptomyces avermitilis MA-4680 1214592 NP_824751.1 CDS galK NC_003155.4 4423526 4424671 R galactokinase complement(4423526..4424671) Streptomyces avermitilis MA-4680 1210771 NP_824752.1 CDS galE1 NC_003155.4 4424675 4425634 R UDP-glucose 4-epimerase complement(4424675..4425634) Streptomyces avermitilis MA-4680 1210772 NP_824753.1 CDS galT NC_003155.4 4425631 4426716 R galactose-1-phosphate uridylyltransferase complement(4425631..4426716) Streptomyces avermitilis MA-4680 1210773 NP_824754.1 CDS SAV_3577 NC_003155.4 4426894 4428603 D Na+/galactose cotransporter 4426894..4428603 Streptomyces avermitilis MA-4680 1214593 NP_824755.1 CDS SAV_3578 NC_003155.4 4428625 4428912 D hypothetical protein 4428625..4428912 Streptomyces avermitilis MA-4680 1214594 NP_824756.1 CDS SAV_3579 NC_003155.4 4429108 4429905 D PF07398: Protein of unknown function (DUF1503); hypothetical protein 4429108..4429905 Streptomyces avermitilis MA-4680 1214595 NP_824757.1 CDS SAV_3580 NC_003155.4 4430349 4430834 D hypothetical protein 4430349..4430834 Streptomyces avermitilis MA-4680 1214596 NP_824758.1 CDS SAV_3581 NC_003155.4 4430980 4431705 R two-component system response regulator complement(4430980..4431705) Streptomyces avermitilis MA-4680 1214597 NP_824759.1 CDS SAV_3582 NC_003155.4 4431956 4433449 R PF01011: PQQ enzyme repeat; hypothetical protein complement(4431956..4433449) Streptomyces avermitilis MA-4680 1214598 NP_824760.1 CDS SAV_3583 NC_003155.4 4433916 4435787 R hypothetical protein complement(4433916..4435787) Streptomyces avermitilis MA-4680 1214599 NP_824761.1 CDS SAV_3584 NC_003155.4 4436011 4437816 R ABC transporter ATP-binding protein complement(4436011..4437816) Streptomyces avermitilis MA-4680 1214600 NP_824762.1 CDS SAV_3585 NC_003155.4 4437912 4439246 R PF01757: Acyltransferase family; hypothetical protein complement(4437912..4439246) Streptomyces avermitilis MA-4680 1214601 NP_824763.1 CDS cmek NC_003155.4 4439401 4440294 R catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(4439401..4440294) Streptomyces avermitilis MA-4680 1210774 NP_824764.1 CDS ksgA NC_003155.4 4440310 4441197 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(4440310..4441197) Streptomyces avermitilis MA-4680 1210775 NP_824765.1 CDS SAV_3588 NC_003155.4 4441559 4443094 R PF03990: Domain of unknown function (DUF348); hypothetical protein complement(4441559..4443094) Streptomyces avermitilis MA-4680 1214602 NP_824766.1 CDS SAV_3589 NC_003155.4 4443175 4444062 R deoxyribonuclease complement(4443175..4444062) Streptomyces avermitilis MA-4680 1214603 NP_824767.1 CDS SAV_3590 NC_003155.4 4444182 4444598 R hypothetical protein complement(4444182..4444598) Streptomyces avermitilis MA-4680 1214604 NP_824768.1 CDS SAV_3591 NC_003155.4 4444966 4445832 R tetrapyrrole methylase complement(4444966..4445832) Streptomyces avermitilis MA-4680 1214605 NP_824769.1 CDS SAV_3592 NC_003155.4 4445895 4447634 D PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; integral membrane protein 4445895..4447634 Streptomyces avermitilis MA-4680 1214606 NP_824770.1 CDS SAV_3593 NC_003155.4 4449642 4450097 D PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region; hypothetical protein 4449642..4450097 Streptomyces avermitilis MA-4680 1214607 NP_824771.1 CDS SAV_3594 NC_003155.4 4450251 4451030 D hypothetical protein 4450251..4451030 Streptomyces avermitilis MA-4680 1214608 NP_824772.1 CDS SAV_3595 NC_003155.4 4451252 4451962 D hypothetical protein 4451252..4451962 Streptomyces avermitilis MA-4680 1214609 NP_824773.1 CDS SAV_3596 NC_003155.4 4451880 4452179 R hypothetical protein complement(4451880..4452179) Streptomyces avermitilis MA-4680 1214610 NP_824774.1 CDS SAV_3597 NC_003155.4 4452893 4453570 R PF02683: Cytochrome C biogenesis protein transmembrane region; hypothetical protein complement(4452893..4453570) Streptomyces avermitilis MA-4680 1214611 NP_824775.1 CDS SAV_3598 NC_003155.4 4454104 4454766 D hypothetical protein 4454104..4454766 Streptomyces avermitilis MA-4680 1214612 NP_824776.1 CDS SAV_3599 NC_003155.4 4454905 4456275 D peroxidase 4454905..4456275 Streptomyces avermitilis MA-4680 1214613 NP_824777.1 CDS SAV_3600 NC_003155.4 4456330 4457460 D hypothetical protein 4456330..4457460 Streptomyces avermitilis MA-4680 1214614 NP_824778.1 CDS gadB1 NC_003155.4 4457596 4458960 D PF00282: Pyridoxal-dependent decarboxylase conserved domain; glutamate decarboxylase 4457596..4458960 Streptomyces avermitilis MA-4680 1210776 NP_824779.1 CDS SAV_3602 NC_003155.4 4459065 4460207 R hypothetical protein complement(4459065..4460207) Streptomyces avermitilis MA-4680 1214615 NP_824780.1 CDS pbp3 NC_003155.4 4460304 4461935 D PF05223: NTF2-like N-terminal transpeptidase domain; penicillin-binding protein 4460304..4461935 Streptomyces avermitilis MA-4680 1210777 NP_824781.1 CDS pbp4 NC_003155.4 4462029 4463702 D PF05223: NTF2-like N-terminal transpeptidase domain; penicillin-binding protein 4462029..4463702 Streptomyces avermitilis MA-4680 1210778 NP_824782.1 CDS ssgA6 NC_003155.4 4463747 4464088 R PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein complement(4463747..4464088) Streptomyces avermitilis MA-4680 1214616 NP_824783.1 CDS cbiM NC_003155.4 4464253 4465308 D cobalt ABC transporter permease component 4464253..4465308 Streptomyces avermitilis MA-4680 1214617 NP_824784.1 CDS cbiQ NC_003155.4 4465310 4466071 D cobalt ABC transporter permease component 4465310..4466071 Streptomyces avermitilis MA-4680 1214618 NP_824785.1 CDS SAV_3608 NC_003155.4 4466086 4466874 D ABC transporter ATP-binding protein 4466086..4466874 Streptomyces avermitilis MA-4680 1214619 NP_824786.1 CDS SAV_3609 NC_003155.4 4466871 4467332 D MarR family transcriptional regulator 4466871..4467332 Streptomyces avermitilis MA-4680 1214620 NP_824787.1 CDS ohrB1 NC_003155.4 4467529 4467933 D organic hydroperoxide resistance protein 4467529..4467933 Streptomyces avermitilis MA-4680 1210779 NP_824788.1 CDS SAV_3611 NC_003155.4 4467965 4469167 D esterase 4467965..4469167 Streptomyces avermitilis MA-4680 1214621 NP_824789.1 CDS SAV_3612 NC_003155.4 4469212 4469487 R hypothetical protein complement(4469212..4469487) Streptomyces avermitilis MA-4680 1214622 NP_824790.1 CDS SAV_3613 NC_003155.4 4469586 4470431 R PF00892: Integral membrane protein DUF6; integral membrane protein complement(4469586..4470431) Streptomyces avermitilis MA-4680 1214623 NP_824791.1 CDS SAV_3614 NC_003155.4 4470428 4470979 R PF04073: YbaK / prolyl-tRNA synthetases associated domain; hypothetical protein complement(4470428..4470979) Streptomyces avermitilis MA-4680 1214624 NP_824792.1 CDS SAV_3615 NC_003155.4 4471011 4471199 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(4471011..4471199) Streptomyces avermitilis MA-4680 1214625 NP_824793.1 CDS SAV_3617 NC_003155.4 4471196 4471843 R DNA-binding protein complement(4471196..4471843) Streptomyces avermitilis MA-4680 1214626 NP_824794.1 CDS SAV_3616 NC_003155.4 4471682 4472491 D hypothetical protein 4471682..4472491 Streptomyces avermitilis MA-4680 1214627 NP_824795.1 CDS SAV_3618 NC_003155.4 4472574 4474799 R PF03176: MMPL family; transmembrane transport protein complement(4472574..4474799) Streptomyces avermitilis MA-4680 1214628 NP_824796.1 CDS SAV_3619 NC_003155.4 4474929 4475519 R TetR family transcriptional regulator complement(4474929..4475519) Streptomyces avermitilis MA-4680 1214629 NP_824797.1 CDS SAV_3620 NC_003155.4 4475706 4479011 D PF03572: Peptidase family S41; protease 4475706..4479011 Streptomyces avermitilis MA-4680 1214630 NP_824798.1 CDS SAV_3621 NC_003155.4 4479074 4479247 R hypothetical protein complement(4479074..4479247) Streptomyces avermitilis MA-4680 1214631 NP_824799.1 CDS SAV_3622 NC_003155.4 4479277 4479522 R hypothetical protein complement(4479277..4479522) Streptomyces avermitilis MA-4680 1214632 NP_824800.1 CDS SAV_3623 NC_003155.4 4479600 4480484 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(4479600..4480484) Streptomyces avermitilis MA-4680 1214633 NP_824801.1 CDS SAV_3624 NC_003155.4 4480481 4481404 R PF00561: alpha/beta hydrolase fold; hydrolase complement(4480481..4481404) Streptomyces avermitilis MA-4680 1214634 NP_824802.1 CDS SAV_3625 NC_003155.4 4481401 4482963 R PF00743: Flavin-binding monooxygenase-like; monooxygenase complement(4481401..4482963) Streptomyces avermitilis MA-4680 1214635 NP_824803.1 CDS SAV_3626 NC_003155.4 4483072 4483740 D MerR family transcriptional regulator 4483072..4483740 Streptomyces avermitilis MA-4680 1214636 NP_824804.1 CDS exoA NC_003155.4 4483778 4484641 R exodeoxyribonuclease complement(4483778..4484641) Streptomyces avermitilis MA-4680 1210780 NP_824805.1 CDS SAV_3627 NC_003155.4 4484640 4485131 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 4484640..4485131 Streptomyces avermitilis MA-4680 1214637 NP_824806.1 CDS SAV_3629 NC_003155.4 4485157 4485609 R protein complement(4485157..4485609) Streptomyces avermitilis MA-4680 1214638 NP_824807.1 CDS SAV_3630 NC_003155.4 4485804 4486463 R two-component system response regulator complement(4485804..4486463) Streptomyces avermitilis MA-4680 1214639 NP_824808.1 CDS SAV_3631 NC_003155.4 4486436 4487725 R two-component system sensor kinase complement(4486436..4487725) Streptomyces avermitilis MA-4680 1214640 NP_824809.1 CDS SAV_3632 NC_003155.4 4488112 4489959 D AfsR homolog, PF03704: Bacterial transcriptional activator domain; regulatory protein 4488112..4489959 Streptomyces avermitilis MA-4680 1214641 NP_824810.1 CDS SAV_3633 NC_003155.4 4490080 4490592 D PF00597: DedA family; hypothetical protein 4490080..4490592 Streptomyces avermitilis MA-4680 1214642 NP_824811.1 CDS SAV_3634 NC_003155.4 4490744 4491490 D ABC transporter ATP-binding protein 4490744..4491490 Streptomyces avermitilis MA-4680 1214643 NP_824812.1 CDS SAV_3635 NC_003155.4 4491484 4493940 D ABC transporter permease 4491484..4493940 Streptomyces avermitilis MA-4680 1214644 NP_824813.1 CDS SAV_3636 NC_003155.4 4494250 4495185 R nrps2 gene cluster; SyrP-like protein complement(4494250..4495185) Streptomyces avermitilis MA-4680 1214645 NP_824814.1 CDS pptA4 NC_003155.4 4495182 4495976 R nrps2 gene cluster, PF01648: 4'-phosphopantetheinyl transferase superfamily; phosphopantetheinyl transferase complement(4495182..4495976) Streptomyces avermitilis MA-4680 1210781 NP_824815.1 CDS SAV_3638 NC_003155.4 4496016 4496951 R nrps2 gene cluster; SyrP-like protein complement(4496016..4496951) Streptomyces avermitilis MA-4680 1214646 NP_824816.1 CDS SAV_3639 NC_003155.4 4496955 4497704 R nrps2 gene cluster; thioesterase complement(4496955..4497704) Streptomyces avermitilis MA-4680 1214647 NP_824817.1 CDS SAV_3640 NC_003155.4 4497725 4499077 R nrps2 gene cluster, PF07690: Major Facilitator Superfamily; multidrug resistance protein complement(4497725..4499077) Streptomyces avermitilis MA-4680 1214648 NP_824818.1 CDS SAV_3641 NC_003155.4 4499074 4499997 R nrps2 gene cluster; ornithine carbamoyltransferase complement(4499074..4499997) Streptomyces avermitilis MA-4680 1214649 NP_824819.1 CDS nrps2-1 NC_003155.4 4500084 4511144 R nrps2 gene cluster; non-ribosomal peptide synthetase complement(4500084..4511144) Streptomyces avermitilis MA-4680 1214650 NP_824820.1 CDS nrps2-2 NC_003155.4 4511156 4516285 R nrps2 gene cluster, NRPS involved in dihydroxy-benzoyl-glycine biosynthesis; non-ribosomal peptide synthetase complement(4511156..4516285) Streptomyces avermitilis MA-4680 1214651 NP_824821.1 CDS SAV_3644 NC_003155.4 4516329 4516595 R nrps2 gene cluster; MbtH-like protein complement(4516329..4516595) Streptomyces avermitilis MA-4680 1214652 NP_824822.1 CDS arcB2 NC_003155.4 4516629 4517633 R nrps2 gene cluster; ornithine cyclodeaminase complement(4516629..4517633) Streptomyces avermitilis MA-4680 1210782 NP_824823.1 CDS SAV_3646 NC_003155.4 4517725 4518525 R nrps2 gene cluster; methyltransferase complement(4517725..4518525) Streptomyces avermitilis MA-4680 1214653 NP_824824.1 CDS nrps2-3 NC_003155.4 4518522 4519862 R nrps2 gene cluster; non-ribosomal peptide synthetase complement(4518522..4519862) Streptomyces avermitilis MA-4680 1214654 NP_824825.1 CDS cysK2 NC_003155.4 4519876 4520859 R nrps2 gene cluster; cysteine synthase complement(4519876..4520859) Streptomyces avermitilis MA-4680 1210783 NP_824826.1 CDS SAV_3649 NC_003155.4 4521113 4521379 R nrps2 gene cluster; peptide carrier protein complement(4521113..4521379) Streptomyces avermitilis MA-4680 1214655 NP_824827.1 CDS fadE25 NC_003155.4 4521379 4523208 R nrps2 gene cluster, PF02770: Acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase complement(4521379..4523208) Streptomyces avermitilis MA-4680 1210784 NP_824828.1 CDS nrps2-4 NC_003155.4 4523205 4526990 R nrps2 gene cluster; non-ribosomal peptide synthetase/acyl-CoA dehydrogenase fusion protein complement(4523205..4526990) Streptomyces avermitilis MA-4680 1214656 NP_824829.1 CDS SAV_3652 NC_003155.4 4527167 4527892 R isomerase complement(4527167..4527892) Streptomyces avermitilis MA-4680 1214657 NP_824830.1 CDS fabG4 NC_003155.4 4527901 4528842 R pks8 gene cluster, PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase complement(4527901..4528842) Streptomyces avermitilis MA-4680 1210785 NP_824831.1 CDS fabA NC_003155.4 4528854 4529351 R pks8 gene cluster; 3-hydroxyacyl-ACP dehydratase complement(4528854..4529351) Streptomyces avermitilis MA-4680 1210786 NP_824832.1 CDS SAV_3655 NC_003155.4 4529354 4529818 R pks8 gene cluster; dehydratase complement(4529354..4529818) Streptomyces avermitilis MA-4680 1214658 NP_824833.1 CDS pks8-1 NC_003155.4 4529815 4530078 R pks8 gene cluster; ACP complement(4529815..4530078) Streptomyces avermitilis MA-4680 1214659 NP_824834.1 CDS pks8-2 NC_003155.4 4530195 4531313 R pks8 gene cluster; 3-oxoacyl-ACP synthase I complement(4530195..4531313) Streptomyces avermitilis MA-4680 1214660 NP_824835.1 CDS pks8-3 NC_003155.4 4531440 4532255 R pks8 gene cluster; 3-oxoacyl-ACP reductase complement(4531440..4532255) Streptomyces avermitilis MA-4680 1214661 NP_824836.1 CDS pks8-4 NC_003155.4 4532239 4533351 R pks8 gene cluster; 3-oxoacyl-ACP synthase II complement(4532239..4533351) Streptomyces avermitilis MA-4680 1214662 NP_824837.1 CDS pks8-5 NC_003155.4 4533377 4534696 R pks8 gene cluster; 3-oxoacyl-ACP synthase I complement(4533377..4534696) Streptomyces avermitilis MA-4680 1214663 NP_824838.1 CDS SAV_3661 NC_003155.4 4534714 4535697 R pks8 gene cluster; hypothetical protein complement(4534714..4535697) Streptomyces avermitilis MA-4680 1214664 NP_824839.1 CDS SAV_3662 NC_003155.4 4535694 4536419 R pks8 gene cluster, PF00561: alpha/beta hydrolase fold; hydrolase complement(4535694..4536419) Streptomyces avermitilis MA-4680 1214665 NP_824840.1 CDS pks8-6 NC_003155.4 4536612 4537697 R pks8 gene cluster; 3-oxoacyl-ACP synthase I complement(4536612..4537697) Streptomyces avermitilis MA-4680 1214666 NP_824841.1 CDS pks8-7 NC_003155.4 4537694 4538857 R pks8 gene cluster; 3-oxoacyl-ACP synthase II complement(4537694..4538857) Streptomyces avermitilis MA-4680 1214667 NP_824842.1 CDS pks8-8 NC_003155.4 4538875 4540161 R pks8 gene cluster; 3-oxoacyl-ACP synthase I complement(4538875..4540161) Streptomyces avermitilis MA-4680 1214668 NP_824843.1 CDS pks8-9 NC_003155.4 4540196 4540450 R pks8 gene cluster; ACP complement(4540196..4540450) Streptomyces avermitilis MA-4680 1214669 NP_824844.1 CDS SAV_3667 NC_003155.4 4540555 4541568 R LuxR-family transcriptional regulatory protein; erythropoiesis-stimulating protein complement(4540555..4541568) Streptomyces avermitilis MA-4680 1214670 NP_824845.1 CDS SAV_3668 NC_003155.4 4542661 4544010 R hypothetical protein complement(4542661..4544010) Streptomyces avermitilis MA-4680 1214671 NP_824846.1 CDS rimJ NC_003155.4 4544195 4544665 R ribosomal-protein-alanine N-acetyltransferase complement(4544195..4544665) Streptomyces avermitilis MA-4680 1210788 NP_824847.1 CDS moaB NC_003155.4 4544851 4545390 R probable molybdenum cofactor biosynthesis protein; molybdopterin biosynthesis protein complement(4544851..4545390) Streptomyces avermitilis MA-4680 1210789 NP_824848.1 CDS moaC NC_003155.4 4545387 4545899 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(4545387..4545899) Streptomyces avermitilis MA-4680 1210790 NP_824849.1 CDS moaA1 NC_003155.4 4545984 4547258 R molybdopterin biosynthesis protein complement(4545984..4547258) Streptomyces avermitilis MA-4680 1210791 NP_824850.1 CDS gtaB NC_003155.4 4547311 4548213 R UTP:glucose-1-phosphate uridylyltransferase complement(4547311..4548213) Streptomyces avermitilis MA-4680 1210792 NP_824851.1 CDS SAV_3674 NC_003155.4 4548308 4548931 D ligase 4548308..4548931 Streptomyces avermitilis MA-4680 1214672 NP_824852.1 CDS pacB1 NC_003155.4 4549001 4551811 R PF01804: Penicillin amidase; penicillin acylase complement(4549001..4551811) Streptomyces avermitilis MA-4680 1214673 NP_824853.1 CDS SAV_3676 NC_003155.4 4552050 4553621 D the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 4552050..4553621 Streptomyces avermitilis MA-4680 1214674 NP_824854.1 CDS SAV_3677 NC_003155.4 4553938 4555236 D PF07690: Major Facilitator Superfamily; ABC transporter permease 4553938..4555236 Streptomyces avermitilis MA-4680 1214675 NP_824855.1 CDS SAV_3678 NC_003155.4 4555305 4555646 D hypothetical protein 4555305..4555646 Streptomyces avermitilis MA-4680 1214676 NP_824856.1 CDS mtaP NC_003155.4 4555722 4556555 D Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 4555722..4556555 Streptomyces avermitilis MA-4680 1210793 NP_824857.1 CDS SAV_3680 NC_003155.4 4556821 4557315 D PF06981: Flp pilus assembly protein CpaB; hypothetical protein 4556821..4557315 Streptomyces avermitilis MA-4680 1214677 NP_824858.1 CDS mscL NC_003155.4 4557442 4557918 D mechanosensitive channel 4557442..4557918 Streptomyces avermitilis MA-4680 1210794 NP_824859.1 CDS SAV_3682 NC_003155.4 4557974 4558150 R hypothetical protein complement(4557974..4558150) Streptomyces avermitilis MA-4680 1214678 NP_824860.1 CDS SAV_3683 NC_003155.4 4558240 4559496 D PF06772: Bacterial low temperature requirement A protein (LtrA); hypothetical protein 4558240..4559496 Streptomyces avermitilis MA-4680 1214679 NP_824861.1 CDS SAV_3684 NC_003155.4 4559528 4560556 D PF03576: peptidase family T4; hypothetical protein 4559528..4560556 Streptomyces avermitilis MA-4680 1214680 NP_824862.1 CDS SAV_3685 NC_003155.4 4560793 4562019 D PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein 4560793..4562019 Streptomyces avermitilis MA-4680 1214681 NP_824863.1 CDS SAV_3686 NC_003155.4 4562200 4562949 D hypothetical protein 4562200..4562949 Streptomyces avermitilis MA-4680 1214682 NP_824864.1 CDS SAV_3687 NC_003155.4 4563070 4563360 R hypothetical protein complement(4563070..4563360) Streptomyces avermitilis MA-4680 1214683 NP_824865.1 CDS fruA NC_003155.4 4563555 4565669 R fructose-specific permease complement(4563555..4565669) Streptomyces avermitilis MA-4680 1210795 NP_824866.1 CDS fruB NC_003155.4 4565839 4566792 R 1-phosphofructokinase complement(4565839..4566792) Streptomyces avermitilis MA-4680 1210796 NP_824867.1 CDS SAV_3690 NC_003155.4 4566789 4567550 R DeoR family transcriptional regulator complement(4566789..4567550) Streptomyces avermitilis MA-4680 1214684 NP_824868.1 CDS SAV_3691 NC_003155.4 4567874 4569388 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(4567874..4569388) Streptomyces avermitilis MA-4680 1214685 NP_824869.1 CDS SAV_3692 NC_003155.4 4569451 4570443 D DeoR family transcriptional regulator 4569451..4570443 Streptomyces avermitilis MA-4680 1214686 NP_824870.1 CDS SAV_3693 NC_003155.4 4570496 4571203 R TetR family transcriptional regulator complement(4570496..4571203) Streptomyces avermitilis MA-4680 1214687 NP_824871.1 CDS sig30 NC_003155.4 4572086 4573081 R sigma-70 family; RNA polymerase sigma factor complement(4572086..4573081) Streptomyces avermitilis MA-4680 1210797 NP_824872.1 CDS bar NC_003155.4 4573253 4573771 D PF00583: Acetyltransferase (GNAT) family; phosphinothricin N-acetyltransferase 4573253..4573771 Streptomyces avermitilis MA-4680 1210798 NP_824873.1 CDS SAV_3696 NC_003155.4 4573801 4574562 R PF02900: catalytic LigB subunit of aromatic ring-opening dioxygenase; hypothetical protein complement(4573801..4574562) Streptomyces avermitilis MA-4680 1214688 NP_824874.1 CDS SAV_3697 NC_003155.4 4574728 4575282 D MarR family transcriptional regulator 4574728..4575282 Streptomyces avermitilis MA-4680 1214689 NP_824875.1 CDS SAV_3698 NC_003155.4 4575383 4576933 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(4575383..4576933) Streptomyces avermitilis MA-4680 1214690 NP_824876.1 CDS SAV_3699 NC_003155.4 4577150 4577794 R TetR family transcriptional regulator complement(4577150..4577794) Streptomyces avermitilis MA-4680 1214691 NP_824877.1 CDS SAV_3700 NC_003155.4 4578033 4579352 D hypothetical protein 4578033..4579352 Streptomyces avermitilis MA-4680 1214692 NP_824878.1 CDS SAV_3701 NC_003155.4 4579518 4581236 D IclR family transcriptional regulator 4579518..4581236 Streptomyces avermitilis MA-4680 1214693 NP_824879.1 CDS SAV_3702 NC_003155.4 4581428 4582084 D TetR family transcriptional regulator 4581428..4582084 Streptomyces avermitilis MA-4680 1214694 NP_824880.1 CDS SAV_3703 NC_003155.4 4582127 4582990 R TetR family transcriptional regulator complement(4582127..4582990) Streptomyces avermitilis MA-4680 1214695 NP_824881.1 CDS cyp17 NC_003155.4 4583057 4584481 R CYP154B2, avaR is located at upstream; cytochrome P450 complement(4583057..4584481) Streptomyces avermitilis MA-4680 1210799 NP_824882.1 CDS avaR NC_003155.4 4584571 4585275 R gamma-butyrolactone receptor protein complement(4584571..4585275) Streptomyces avermitilis MA-4680 1210800 NP_824883.1 CDS SAV_3706 NC_003155.4 4585720 4587741 D acyl-CoA oxidase 4585720..4587741 Streptomyces avermitilis MA-4680 1214696 NP_824884.1 CDS adhA5 NC_003155.4 4588309 4589343 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 4588309..4589343 Streptomyces avermitilis MA-4680 1214697 NP_824885.1 CDS int7 NC_003155.4 4590544 4591725 R PF00589: Phage integrase family; phage integrase complement(4590544..4591725) Streptomyces avermitilis MA-4680 1210802 NP_824886.1 CDS xis NC_003155.4 4591725 4591925 R phage excisionase complement(4591725..4591925) Streptomyces avermitilis MA-4680 1210803 NP_824887.1 CDS SAV_3710 NC_003155.4 4592037 4592204 R hypothetical protein complement(4592037..4592204) Streptomyces avermitilis MA-4680 1214698 NP_824888.1 CDS SAV_3711 NC_003155.4 4592396 4593871 R ATP-binding protein complement(4592396..4593871) Streptomyces avermitilis MA-4680 1214699 NP_824889.1 CDS SAV_3712 NC_003155.4 4593874 4594734 R hypothetical protein complement(4593874..4594734) Streptomyces avermitilis MA-4680 1214700 NP_824890.1 CDS SAV_3713 NC_003155.4 4594875 4595906 D hypothetical protein 4594875..4595906 Streptomyces avermitilis MA-4680 1214701 NP_824891.1 CDS SAV_3714 NC_003155.4 4595934 4596389 R hypothetical protein complement(4595934..4596389) Streptomyces avermitilis MA-4680 1214702 NP_824892.1 CDS traB1 NC_003155.4 4596559 4598637 R sporulation-related protein complement(4596559..4598637) Streptomyces avermitilis MA-4680 1210804 NP_824893.1 CDS traA1 NC_003155.4 4598651 4599220 R sporulation-related protein complement(4598651..4599220) Streptomyces avermitilis MA-4680 1210805 NP_824894.1 CDS SAV_3717 NC_003155.4 4599240 4599740 R hypothetical protein complement(4599240..4599740) Streptomyces avermitilis MA-4680 1214703 NP_824895.1 CDS SAV_3718 NC_003155.4 4599769 4600851 R PF01507: Phosphoadenosine phosphosulfate reductase family; hypothetical protein complement(4599769..4600851) Streptomyces avermitilis MA-4680 1214704 NP_824896.1 CDS SAV_3719 NC_003155.4 4600848 4601825 R SpdB homolog; hypothetical protein complement(4600848..4601825) Streptomyces avermitilis MA-4680 1214705 NP_824897.1 CDS SAV_3720 NC_003155.4 4601822 4602112 R hypothetical protein complement(4601822..4602112) Streptomyces avermitilis MA-4680 1214706 NP_824898.1 CDS SAV_3721 NC_003155.4 4602727 4603485 D PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator 4602727..4603485 Streptomyces avermitilis MA-4680 1214707 NP_824899.1 CDS SAV_3722 NC_003155.4 4605720 4607084 D IS4 family; IS4 family transposase 4605720..4607084 Streptomyces avermitilis MA-4680 1214708 NP_824900.1 CDS SAV_3723 NC_003155.4 4607342 4608352 R hypothetical protein complement(4607342..4608352) Streptomyces avermitilis MA-4680 1214709 NP_824901.1 CDS SAV_3724 NC_003155.4 4608844 4609239 R hypothetical protein complement(4608844..4609239) Streptomyces avermitilis MA-4680 1214710 NP_824902.1 CDS SAV_3725 NC_003155.4 4609420 4610523 R hypothetical protein complement(4609420..4610523) Streptomyces avermitilis MA-4680 1214711 NP_824903.1 CDS SAV_3726 NC_003155.4 4610608 4612356 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein complement(4610608..4612356) Streptomyces avermitilis MA-4680 1214712 NP_824904.1 CDS SAV_3727 NC_003155.4 4612749 4613219 R hypothetical protein complement(4612749..4613219) Streptomyces avermitilis MA-4680 1214713 NP_824905.1 CDS int8 NC_003155.4 4614801 4615940 R PF00589: Phage integrase family; integrase complement(4614801..4615940) Streptomyces avermitilis MA-4680 1214714 NP_824906.1 CDS repSA1 NC_003155.4 4616145 4617458 R replication initiation protein complement(4616145..4617458) Streptomyces avermitilis MA-4680 1210806 NP_824907.1 CDS spdD1 NC_003155.4 4617607 4617852 R SpdD protein complement(4617607..4617852) Streptomyces avermitilis MA-4680 1214715 NP_824908.1 CDS SAV_3731 NC_003155.4 4617877 4618071 R hypothetical protein complement(4617877..4618071) Streptomyces avermitilis MA-4680 1214716 NP_824909.1 CDS spdB1 NC_003155.4 4618088 4618279 R mobile element transfer protein SpdB complement(4618088..4618279) Streptomyces avermitilis MA-4680 1210807 NP_824910.1 CDS spdA1 NC_003155.4 4618292 4618918 R mobile element transfer protein SpdA complement(4618292..4618918) Streptomyces avermitilis MA-4680 1210808 NP_824911.1 CDS traSA1 NC_003155.4 4619007 4620386 R plasmid transfer protein complement(4619007..4620386) Streptomyces avermitilis MA-4680 1210809 NP_824912.1 CDS pra1 NC_003155.4 4620386 4620742 R replication activator protein Pra complement(4620386..4620742) Streptomyces avermitilis MA-4680 1210810 NP_824913.1 CDS korSA1 NC_003155.4 4620920 4621708 R PF07702: UbiC transcription regulator-associated; regulatory protein KorSA complement(4620920..4621708) Streptomyces avermitilis MA-4680 1210811 NP_824914.1 CDS SAV_3737 NC_003155.4 4621735 4622223 D MutT-like protein 4621735..4622223 Streptomyces avermitilis MA-4680 1214717 NP_824915.1 CDS SAV_3738 NC_003155.4 4622270 4622698 D regulatory protein 4622270..4622698 Streptomyces avermitilis MA-4680 1214718 NP_824916.1 CDS SAV_3739 NC_003155.4 4622692 4623039 D hypothetical protein 4622692..4623039 Streptomyces avermitilis MA-4680 1214719 NP_824917.1 CDS SAV_3740 NC_003155.4 4623036 4623425 D hypothetical protein 4623036..4623425 Streptomyces avermitilis MA-4680 1214720 NP_824918.1 CDS SAV_3741 NC_003155.4 4623466 4625235 R unclassified IS, PF00665: Integrase core domain; ISmav2-like transposase complement(4623466..4625235) Streptomyces avermitilis MA-4680 1214721 NP_824919.1 CDS SAV_3742 NC_003155.4 4626525 4627730 R hypothetical protein complement(4626525..4627730) Streptomyces avermitilis MA-4680 1214722 NP_824920.1 CDS SAV_3743 NC_003155.4 4630443 4631972 R hypothetical protein complement(4630443..4631972) Streptomyces avermitilis MA-4680 1214723 NP_824921.1 CDS SAV_3744 NC_003155.4 4632395 4632796 D hypothetical protein 4632395..4632796 Streptomyces avermitilis MA-4680 1214724 NP_824922.1 CDS SAV_3745 NC_003155.4 4633048 4633491 D hypothetical protein 4633048..4633491 Streptomyces avermitilis MA-4680 1214725 NP_824923.1 CDS SAV_3746 NC_003155.4 4634597 4636144 D hypothetical protein 4634597..4636144 Streptomyces avermitilis MA-4680 1214726 NP_824924.1 CDS SAV_3747 NC_003155.4 4637051 4637479 D hypothetical protein 4637051..4637479 Streptomyces avermitilis MA-4680 1214727 NP_824925.1 CDS SAV_3748 NC_003155.4 4638366 4639334 R hypothetical protein complement(4638366..4639334) Streptomyces avermitilis MA-4680 1214728 NP_824926.1 CDS SAV_3749 NC_003155.4 4639693 4640202 R hypothetical protein complement(4639693..4640202) Streptomyces avermitilis MA-4680 1214729 NP_824927.1 CDS SAV_3750 NC_003155.4 4640621 4640953 D hypothetical protein 4640621..4640953 Streptomyces avermitilis MA-4680 1214730 NP_824928.1 CDS SAV_3751 NC_003155.4 4641303 4641581 R hypothetical protein complement(4641303..4641581) Streptomyces avermitilis MA-4680 1214731 NP_824929.1 CDS SAV_3752 NC_003155.4 4641822 4643474 R PF01839: FG-GAP repeat; hypothetical protein complement(4641822..4643474) Streptomyces avermitilis MA-4680 1214732 NP_824930.1 CDS SAV_3753 NC_003155.4 4643740 4644273 R hypothetical protein complement(4643740..4644273) Streptomyces avermitilis MA-4680 1214733 NP_824931.1 CDS SAV_3754 NC_003155.4 4644830 4646323 R FAD-dependent oxygenase complement(4644830..4646323) Streptomyces avermitilis MA-4680 1214734 NP_824932.1 CDS ptpB1 NC_003155.4 4646687 4647109 R PF01451: Low molecular weight phosphotyrosine protein phosphatase; low molecular weight protein tyrosine phosphatase complement(4646687..4647109) Streptomyces avermitilis MA-4680 1214735 NP_824933.1 CDS SAV_3755 NC_003155.4 4647099 4647371 D hypothetical protein 4647099..4647371 Streptomyces avermitilis MA-4680 1214736 NP_824934.1 CDS SAV_3757 NC_003155.4 4647424 4647828 R transcription regulator ArsR complement(4647424..4647828) Streptomyces avermitilis MA-4680 1214737 NP_824935.1 CDS SAV_3758 NC_003155.4 4647908 4648378 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 4647908..4648378 Streptomyces avermitilis MA-4680 1214738 NP_824936.1 CDS SAV_3759 NC_003155.4 4648561 4649208 R hypothetical protein complement(4648561..4649208) Streptomyces avermitilis MA-4680 1214739 NP_824937.1 CDS SAV_3760 NC_003155.4 4649384 4649980 R TetR family transcriptional regulator complement(4649384..4649980) Streptomyces avermitilis MA-4680 1214740 NP_824938.1 CDS SAV_3761 NC_003155.4 4650129 4650857 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein 4650129..4650857 Streptomyces avermitilis MA-4680 1214741 NP_824939.1 CDS SAV_3762 NC_003155.4 4650952 4651512 R hypothetical protein complement(4650952..4651512) Streptomyces avermitilis MA-4680 1214742 NP_824940.1 CDS SAV_3763 NC_003155.4 4651594 4652211 R LysE family efflux protein complement(4651594..4652211) Streptomyces avermitilis MA-4680 1214743 NP_824941.1 CDS SAV_3764 NC_003155.4 4652323 4652781 D transcription regulator AsnC 4652323..4652781 Streptomyces avermitilis MA-4680 1214744 NP_824942.1 CDS SAV_3765 NC_003155.4 4652819 4654066 R PF01041: DegT/DnrJ/EryC1/StrS aminotransferase family; hypothetical protein complement(4652819..4654066) Streptomyces avermitilis MA-4680 1214745 NP_824943.1 CDS SAV_3766 NC_003155.4 4654181 4655296 R hypothetical protein complement(4654181..4655296) Streptomyces avermitilis MA-4680 1214746 NP_824944.1 CDS SAV_3767 NC_003155.4 4655867 4656193 D hypothetical protein 4655867..4656193 Streptomyces avermitilis MA-4680 1214747 NP_824945.1 CDS SAV_3768 NC_003155.4 4656757 4657602 R integral membrane protein complement(4656757..4657602) Streptomyces avermitilis MA-4680 1214748 NP_824946.1 CDS SAV_3769 NC_003155.4 4658158 4660647 R PF01433: Peptidase family M1; aminopeptidase complement(4658158..4660647) Streptomyces avermitilis MA-4680 1214749 NP_824947.1 CDS SAV_3770 NC_003155.4 4660850 4662259 R hypothetical protein complement(4660850..4662259) Streptomyces avermitilis MA-4680 1214750 NP_824948.1 CDS SAV_3771 NC_003155.4 4662186 4663709 R PF05672: E-MAP-115 family; hypothetical protein complement(4662186..4663709) Streptomyces avermitilis MA-4680 1214751 NP_824949.1 CDS SAV_3772 NC_003155.4 4663715 4666081 R hypothetical protein complement(4663715..4666081) Streptomyces avermitilis MA-4680 1214752 NP_824950.1 CDS SAV_3773 NC_003155.4 4666101 4666883 R hypothetical protein complement(4666101..4666883) Streptomyces avermitilis MA-4680 1214753 NP_824951.1 CDS SAV_3774 NC_003155.4 4667076 4667594 D hypothetical protein 4667076..4667594 Streptomyces avermitilis MA-4680 1214754 NP_824952.1 CDS SAV_3775 NC_003155.4 4667663 4668403 R transcriptional regulator complement(4667663..4668403) Streptomyces avermitilis MA-4680 1214755 NP_824953.1 CDS SAV_3776 NC_003155.4 4668521 4669753 R PF07690: Major Facilitator Superfamily; integral membrane protein complement(4668521..4669753) Streptomyces avermitilis MA-4680 1214756 NP_824954.1 CDS SAV_3777 NC_003155.4 4669812 4670795 D transcriptional regulator 4669812..4670795 Streptomyces avermitilis MA-4680 1214757 NP_824955.1 CDS bsaA NC_003155.4 4670805 4671314 D glutathione peroxidase 4670805..4671314 Streptomyces avermitilis MA-4680 1210812 NP_824956.1 CDS SAV_3779 NC_003155.4 4671387 4672286 D MerR family transcriptional regulator 4671387..4672286 Streptomyces avermitilis MA-4680 1214758 NP_824957.1 CDS SAV_3780 NC_003155.4 4672352 4674325 R PF07695: 7TM diverse intracellular signalling; integral membrane protein complement(4672352..4674325) Streptomyces avermitilis MA-4680 1214759 NP_824958.1 CDS dacC NC_003155.4 4674500 4677166 R PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase complement(4674500..4677166) Streptomyces avermitilis MA-4680 1210813 NP_824959.1 CDS SAV_3782 NC_003155.4 4677405 4678160 D PF05719: Golgi phosphoprotein 3 (GPP34); hypothetical protein 4677405..4678160 Streptomyces avermitilis MA-4680 1214760 NP_824960.1 CDS SAV_3783 NC_003155.4 4678590 4679447 D DNA-binding protein 4678590..4679447 Streptomyces avermitilis MA-4680 1214761 NP_824961.1 CDS SAV_3784 NC_003155.4 4679677 4679886 D PF04149: Domain of unknown function (DUF397); hypothetical protein 4679677..4679886 Streptomyces avermitilis MA-4680 1214762 NP_824962.1 CDS SAV_3785 NC_003155.4 4680104 4680958 R hypothetical protein complement(4680104..4680958) Streptomyces avermitilis MA-4680 1214763 NP_824963.1 CDS SAV_3786 NC_003155.4 4681048 4681833 D PF00106: short chain dehydrogenase; short chain dehydrogenase 4681048..4681833 Streptomyces avermitilis MA-4680 1214764 NP_824964.1 CDS SAV_3787 NC_003155.4 4682066 4683634 D PF00474: Sodium:solute symporter family; sodium-coupled permease 4682066..4683634 Streptomyces avermitilis MA-4680 1214765 NP_824965.1 CDS draG3 NC_003155.4 4683675 4684790 R PF03747: ADP-ribosylglycohydrolase; ADP-ribosylglycohydrolase complement(4683675..4684790) Streptomyces avermitilis MA-4680 1214766 NP_824966.1 CDS SAV_3789 NC_003155.4 4684952 4686358 D PF01839: FG-GAP repeat; hypothetical protein 4684952..4686358 Streptomyces avermitilis MA-4680 1214767 NP_824967.1 CDS mdmB NC_003155.4 4686492 4687670 R macrolide O-acyltransferase complement(4686492..4687670) Streptomyces avermitilis MA-4680 1210814 NP_824968.1 CDS SAV_3791 NC_003155.4 4687844 4688230 D hypothetical protein 4687844..4688230 Streptomyces avermitilis MA-4680 1214768 NP_824969.1 CDS SAV_3792 NC_003155.4 4688318 4690384 R hypothetical protein complement(4688318..4690384) Streptomyces avermitilis MA-4680 1214769 NP_824970.1 CDS SAV_3793 NC_003155.4 4690672 4691025 D hypothetical protein 4690672..4691025 Streptomyces avermitilis MA-4680 1214770 NP_824971.1 CDS fbiC NC_003155.4 4691032 4693617 R 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; FO synthase complement(4691032..4693617) Streptomyces avermitilis MA-4680 1214771 NP_824972.1 CDS SAV_3795 NC_003155.4 4693843 4695351 D PF02231: PHP domain N-terminal region; protein 4693843..4695351 Streptomyces avermitilis MA-4680 1214772 NP_824973.1 CDS SAV_3796 NC_003155.4 4695437 4695844 D PF04075: Domain of unknown function (DUF385); hypothetical protein 4695437..4695844 Streptomyces avermitilis MA-4680 1214773 NP_824974.1 CDS SAV_3797 NC_003155.4 4695867 4697255 D hypothetical protein 4695867..4697255 Streptomyces avermitilis MA-4680 1214774 NP_824975.1 CDS SAV_3798 NC_003155.4 4697299 4698798 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(4697299..4698798) Streptomyces avermitilis MA-4680 1214775 NP_824976.1 CDS SAV_3799 NC_003155.4 4698795 4700525 R D-aminoacylase complement(4698795..4700525) Streptomyces avermitilis MA-4680 1214776 NP_824977.1 CDS SAV_3800 NC_003155.4 4700540 4701580 R PF00296: Luciferase-like monooxygenase; hypothetical protein complement(4700540..4701580) Streptomyces avermitilis MA-4680 1214777 NP_824978.1 CDS SAV_3801 NC_003155.4 4701767 4702543 R PF00106: short chain dehydrogenase; dehydrogenase complement(4701767..4702543) Streptomyces avermitilis MA-4680 1214778 NP_824979.1 CDS SAV_3802 NC_003155.4 4702552 4703481 R PF00296: Luciferase-like monooxygenase; hypothetical protein complement(4702552..4703481) Streptomyces avermitilis MA-4680 1214779 NP_824980.1 CDS SAV_3803 NC_003155.4 4703478 4704737 R PF04909: Amidohydrolase; hypothetical protein complement(4703478..4704737) Streptomyces avermitilis MA-4680 1214780 NP_824981.1 CDS SAV_3804 NC_003155.4 4704929 4707871 D AfsR homolog, PF03704: Bacterial transcriptional activator domain; transcriptional regulator 4704929..4707871 Streptomyces avermitilis MA-4680 1214781 NP_824982.1 CDS SAV_3805 NC_003155.4 4708083 4708346 D hypothetical protein 4708083..4708346 Streptomyces avermitilis MA-4680 1214782 NP_824983.1 CDS fadD16 NC_003155.4 4708540 4710123 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(4708540..4710123) Streptomyces avermitilis MA-4680 1214783 NP_824984.1 CDS ltp2 NC_003155.4 4710253 4711401 D PF02803: Thiolase, C-terminal domain; lipid-transfer protein 4710253..4711401 Streptomyces avermitilis MA-4680 1210815 NP_824985.1 CDS SAV_3808 NC_003155.4 4711403 4711819 D PF01796: Domain of unknown function DUF35; hypothetical protein 4711403..4711819 Streptomyces avermitilis MA-4680 1214784 NP_824986.1 CDS echA10 NC_003155.4 4711798 4712586 D enoyl-CoA hydratase/isomerase 4711798..4712586 Streptomyces avermitilis MA-4680 1210816 NP_824987.1 CDS ephA2 NC_003155.4 4712599 4713600 D PF00561: alpha/beta hydrolase fold; epoxide hydrolase 4712599..4713600 Streptomyces avermitilis MA-4680 1214785 NP_824988.1 CDS SAV_3811 NC_003155.4 4713644 4714243 R hypothetical protein complement(4713644..4714243) Streptomyces avermitilis MA-4680 1214786 NP_824989.1 CDS SAV_3812 NC_003155.4 4714344 4714991 R hypothetical protein complement(4714344..4714991) Streptomyces avermitilis MA-4680 1214787 NP_824990.1 CDS SAV_3813 NC_003155.4 4715060 4715671 R NADPH-dependent FMN reductase complement(4715060..4715671) Streptomyces avermitilis MA-4680 1214788 NP_824991.1 CDS SAV_3814 NC_003155.4 4715668 4715985 R PF01638: Transcriptional regulator; hypothetical protein complement(4715668..4715985) Streptomyces avermitilis MA-4680 1214789 NP_824992.1 CDS SAV_3815 NC_003155.4 4716009 4716572 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 4716009..4716572 Streptomyces avermitilis MA-4680 1214790 NP_824993.1 CDS pkn7 NC_003155.4 4716713 4719061 R AfsK homolog; serine/threonine protein kinase complement(4716713..4719061) Streptomyces avermitilis MA-4680 1210817 NP_824994.1 CDS SAV_3817 NC_003155.4 4719274 4720068 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hydroxylase complement(4719274..4720068) Streptomyces avermitilis MA-4680 1214791 NP_824995.1 CDS SAV_3818 NC_003155.4 4720214 4720849 D TetR family transcriptional regulator 4720214..4720849 Streptomyces avermitilis MA-4680 1214792 NP_824996.1 CDS frcK NC_003155.4 4721114 4721851 D PF00485: Phosphoribulokinase / Uridine kinase family; putative fructose transport system kinase 4721114..4721851 Streptomyces avermitilis MA-4680 1214793 NP_824997.1 CDS SAV_3820 NC_003155.4 4721838 4722311 R PF04075: Domain of unknown function (DUF385); hypothetical protein complement(4721838..4722311) Streptomyces avermitilis MA-4680 1214794 NP_824998.1 CDS fadE9 NC_003155.4 4722311 4723552 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(4722311..4723552) Streptomyces avermitilis MA-4680 1210818 NP_824999.1 CDS SAV_3822 NC_003155.4 4723667 4724836 D PF02803: Thiolase, C-terminal domain; hypothetical protein 4723667..4724836 Streptomyces avermitilis MA-4680 1214795 NP_825000.1 CDS SAV_3823 NC_003155.4 4724859 4726046 R hypothetical protein complement(4724859..4726046) Streptomyces avermitilis MA-4680 1214796 NP_825001.1 CDS pdxH2 NC_003155.4 4726745 4727401 D pyridoxamine 5'-phosphate oxidase 4726745..4727401 Streptomyces avermitilis MA-4680 1214797 NP_825002.1 CDS SAV_3825 NC_003155.4 4727458 4727865 R PF01796: Domain of unknown function DUF35; hypothetical protein complement(4727458..4727865) Streptomyces avermitilis MA-4680 1214798 NP_825003.1 CDS SAV_3826 NC_003155.4 4727862 4728275 R PF07681: DoxX; hypothetical protein complement(4727862..4728275) Streptomyces avermitilis MA-4680 1214799 NP_825004.1 CDS SAV_3827 NC_003155.4 4728525 4729730 D PF00743: Flavin-binding monooxygenase-like; monooxygenase 4728525..4729730 Streptomyces avermitilis MA-4680 1214800 NP_825005.1 CDS SAV_3828 NC_003155.4 4730190 4732331 D pimeloyl-CoA synthetase 4730190..4732331 Streptomyces avermitilis MA-4680 1214801 NP_825006.1 CDS echA11 NC_003155.4 4732417 4733256 D enoyl-CoA hydratase 4732417..4733256 Streptomyces avermitilis MA-4680 1210819 NP_825007.1 CDS SAV_3830 NC_003155.4 4733339 4733938 D PF01613: flavin reductase like domain; NADPH-flavin oxidoreductase 4733339..4733938 Streptomyces avermitilis MA-4680 1214802 NP_825008.1 CDS SAV_3831 NC_003155.4 4733988 4735298 R PF07690: Major Facilitator Superfamily; integral membrane protein complement(4733988..4735298) Streptomyces avermitilis MA-4680 1214803 NP_825009.1 CDS SAV_3832 NC_003155.4 4735370 4736383 D AraC family transcription regulator 4735370..4736383 Streptomyces avermitilis MA-4680 1214804 NP_825010.1 CDS adhA6 NC_003155.4 4736424 4737473 R PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase complement(4736424..4737473) Streptomyces avermitilis MA-4680 1214805 NP_825011.1 CDS fadE8 NC_003155.4 4737486 4738637 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(4737486..4738637) Streptomyces avermitilis MA-4680 1210820 NP_825012.1 CDS SAV_3835 NC_003155.4 4738649 4739554 R PF00106: short chain dehydrogenase; dehydrogenase complement(4738649..4739554) Streptomyces avermitilis MA-4680 1214806 NP_825013.1 CDS SAV_3836 NC_003155.4 4739639 4740574 D PF04199: Putative cyclase; cyclase 4739639..4740574 Streptomyces avermitilis MA-4680 1214807 NP_825014.1 CDS SAV_3837 NC_003155.4 4741128 4741661 R regulatory protein complement(4741128..4741661) Streptomyces avermitilis MA-4680 1214808 NP_825015.1 CDS fadE27 NC_003155.4 4742154 4743026 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(4742154..4743026) Streptomyces avermitilis MA-4680 1210821 NP_825016.1 CDS fadE18 NC_003155.4 4743032 4744186 R PF02770: Acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase complement(4743032..4744186) Streptomyces avermitilis MA-4680 1210822 NP_825017.1 CDS SAV_3840 NC_003155.4 4744186 4745454 R PF04909: Amidohydrolase; hypothetical protein complement(4744186..4745454) Streptomyces avermitilis MA-4680 1214809 NP_825018.1 CDS fadD17 NC_003155.4 4745600 4747099 D similar to bifunctional enzyme MbtA: salicyl-AMP ligase + salicyl-S-ArCP synthetase. PF00501: AMP-binding enzyme; cyclohex-1-ene-1-carboxylate:CoA ligase 4745600..4747099 Streptomyces avermitilis MA-4680 1210823 NP_825019.1 CDS SAV_3842 NC_003155.4 4747103 4747615 R calcium binding protein complement(4747103..4747615) Streptomyces avermitilis MA-4680 1214810 NP_825020.1 CDS SAV_3843 NC_003155.4 4747797 4748177 R PF01740: STAS domain; anti-sigma factor antagonist complement(4747797..4748177) Streptomyces avermitilis MA-4680 1214811 NP_825021.1 CDS sig31 NC_003155.4 4748570 4749151 D ECF subfamily RNA polymerase sigma factor 4748570..4749151 Streptomyces avermitilis MA-4680 1210824 NP_825022.1 CDS SAV_3845 NC_003155.4 4749148 4750632 D PF01391: Collagen triple helix repeat (20 copies); hypothetical protein 4749148..4750632 Streptomyces avermitilis MA-4680 1214812 NP_825023.1 CDS purU NC_003155.4 4750759 4751640 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(4750759..4751640) Streptomyces avermitilis MA-4680 1210825 NP_825024.1 CDS SAV_3847 NC_003155.4 4751772 4752272 R hypothetical protein complement(4751772..4752272) Streptomyces avermitilis MA-4680 1214813 NP_825025.1 CDS SAV_3848 NC_003155.4 4752390 4753676 D lipoprotein 4752390..4753676 Streptomyces avermitilis MA-4680 1214814 NP_825026.1 CDS SAV_3849 NC_003155.4 4753710 4755389 R PF02757: YLP motif; hypothetical protein complement(4753710..4755389) Streptomyces avermitilis MA-4680 1214815 NP_825027.1 CDS SAV_3850 NC_003155.4 4755648 4757033 R transcriptional regulator complement(4755648..4757033) Streptomyces avermitilis MA-4680 1214816 NP_825028.1 CDS SAV_3851 NC_003155.4 4757351 4758004 D hypothetical protein 4757351..4758004 Streptomyces avermitilis MA-4680 1214817 NP_825029.1 CDS SAV_3852 NC_003155.4 4758221 4759012 D ABC transporter ATP-binding protein 4758221..4759012 Streptomyces avermitilis MA-4680 1214818 NP_825030.1 CDS SAV_3853 NC_003155.4 4759009 4760643 D integral membrane transport protein 4759009..4760643 Streptomyces avermitilis MA-4680 1214819 NP_825031.1 CDS SAV_3854 NC_003155.4 4760834 4761757 R PF00561: alpha/beta hydrolase fold; hydrolase complement(4760834..4761757) Streptomyces avermitilis MA-4680 1214820 NP_825032.1 CDS ideR NC_003155.4 4762296 4762988 R iron dependent regulatory protein complement(4762296..4762988) Streptomyces avermitilis MA-4680 1210826 NP_825033.1 CDS SAV_3856 NC_003155.4 4763224 4763979 D PF01380: SIS domain; hypothetical protein 4763224..4763979 Streptomyces avermitilis MA-4680 1214821 NP_825034.1 CDS SAV_3857 NC_003155.4 4764023 4765453 R PF00989: PAS domain; hypothetical protein complement(4764023..4765453) Streptomyces avermitilis MA-4680 1214822 NP_825035.1 CDS pdxH1 NC_003155.4 4766266 4766940 R pyridoxamine 5'-phosphate oxidase complement(4766266..4766940) Streptomyces avermitilis MA-4680 1210827 NP_825036.1 CDS citA2 NC_003155.4 4767277 4768377 D forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; citrate synthase 2 4767277..4768377 Streptomyces avermitilis MA-4680 1210828 NP_825037.1 CDS SAV_3860 NC_003155.4 4768463 4769500 R PF03171: 2OG-Fe(II) oxygenase superfamily; iron/ascorbate-dependent oxidoreductase complement(4768463..4769500) Streptomyces avermitilis MA-4680 1214823 NP_825038.1 CDS SAV_3861 NC_003155.4 4769864 4770511 R hypothetical protein complement(4769864..4770511) Streptomyces avermitilis MA-4680 1214824 NP_825039.1 CDS SAV_3862 NC_003155.4 4770608 4771207 R TetR family transcriptional regulator complement(4770608..4771207) Streptomyces avermitilis MA-4680 1214825 NP_825040.1 CDS echA12 NC_003155.4 4771195 4771929 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(4771195..4771929) Streptomyces avermitilis MA-4680 1210829 NP_825041.1 CDS SAV_3864 NC_003155.4 4771926 4773500 R 4-coumarate:CoA ligase complement(4771926..4773500) Streptomyces avermitilis MA-4680 1214826 NP_825042.1 CDS fadE13 NC_003155.4 4773556 4774716 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(4773556..4774716) Streptomyces avermitilis MA-4680 1210830 NP_825043.1 CDS accA2 NC_003155.4 4774800 4776650 R acetyl/propionyl CoA carboxylase alpha subunit complement(4774800..4776650) Streptomyces avermitilis MA-4680 1210831 NP_825044.1 CDS accD2 NC_003155.4 4776661 4778259 R acetyl/propionyl CoA carboxylase, beta subunit complement(4776661..4778259) Streptomyces avermitilis MA-4680 1210832 NP_825045.1 CDS SAV_3868 NC_003155.4 4778256 4779944 R PF07287: Protein of unknown function (DUF1446); hypothetical protein complement(4778256..4779944) Streptomyces avermitilis MA-4680 1214827 NP_825046.1 CDS SAV_3869 NC_003155.4 4779941 4780744 R PF07398: Protein of unknown function (DUF1503); hypothetical protein complement(4779941..4780744) Streptomyces avermitilis MA-4680 1214828 NP_825047.1 CDS malS2 NC_003155.4 4780954 4782675 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(4780954..4782675) Streptomyces avermitilis MA-4680 1210833 NP_825048.1 CDS SAV_3871 NC_003155.4 4782844 4783797 R PF00892: Integral membrane protein DUF6; integral membrane protein complement(4782844..4783797) Streptomyces avermitilis MA-4680 1214829 NP_825049.1 CDS SAV_3872 NC_003155.4 4783941 4786316 R ABC transporter ATP-binding protein complement(4783941..4786316) Streptomyces avermitilis MA-4680 1214830 NP_825050.1 CDS SAV_3873 NC_003155.4 4786449 4786634 D hypothetical protein 4786449..4786634 Streptomyces avermitilis MA-4680 1214831 NP_825051.1 CDS SAV_3874 NC_003155.4 4786855 4787421 R hypothetical protein complement(4786855..4787421) Streptomyces avermitilis MA-4680 1214832 NP_825052.1 CDS SAV_3875 NC_003155.4 4787452 4787994 R hypothetical protein complement(4787452..4787994) Streptomyces avermitilis MA-4680 1214833 NP_825053.1 CDS SAV_3876 NC_003155.4 4788125 4791073 R PF01565: FAD binding domain; oxidoreductase complement(4788125..4791073) Streptomyces avermitilis MA-4680 1214834 NP_825054.1 CDS cvnA9 NC_003155.4 4791417 4793657 D multi-component regulatory system-9; sensor-like histidine kinase 4791417..4793657 Streptomyces avermitilis MA-4680 1210834 NP_825055.1 CDS cvnB9 NC_003155.4 4793654 4794061 D multi-component regulatory system-9, PF03259: Roadblock/LC7 domain; hypothetical protein 4793654..4794061 Streptomyces avermitilis MA-4680 1210835 NP_825056.1 CDS cvnC9 NC_003155.4 4794058 4794405 D multi-component regulatory system-9, PF05331: Protein of unknown function (DUF742); hypothetical protein 4794058..4794405 Streptomyces avermitilis MA-4680 1210836 NP_825057.1 CDS cvnD9 NC_003155.4 4794479 4795021 D multi-component regulatory system-9; ATP/GTP-binding protein 4794479..4795021 Streptomyces avermitilis MA-4680 1210837 NP_825058.1 CDS cyp18 NC_003155.4 4795018 4796253 D CYP157A2, adjacent to multi-component regulatory system-9; cytochrome P450 hydroxylase 4795018..4796253 Streptomyces avermitilis MA-4680 1210838 NP_825059.1 CDS cyp19 NC_003155.4 4796250 4797452 D CYP154C2, adjacent to CYP157A2; cytochrome P450 hydroxylase 4796250..4797452 Streptomyces avermitilis MA-4680 1210839 NP_825060.1 CDS serC NC_003155.4 4797602 4798720 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 4797602..4798720 Streptomyces avermitilis MA-4680 1214835 NP_825061.1 CDS SAV_3884 NC_003155.4 4798865 4799851 R hypothetical protein complement(4798865..4799851) Streptomyces avermitilis MA-4680 1214836 NP_825062.1 CDS SAV_3885 NC_003155.4 4799980 4800666 D PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein 4799980..4800666 Streptomyces avermitilis MA-4680 1214837 NP_825063.1 CDS SAV_3886 NC_003155.4 4800887 4801681 R PF02353: Cyclopropane-fatty-acyl-phospholipid synthase; hypothetical protein complement(4800887..4801681) Streptomyces avermitilis MA-4680 1214838 NP_825064.1 CDS SAV_3887 NC_003155.4 4801758 4803293 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(4801758..4803293) Streptomyces avermitilis MA-4680 1214839 NP_825065.1 CDS sig32 NC_003155.4 4803733 4804431 D ECF subfamily RNA polymerase sigma factor 4803733..4804431 Streptomyces avermitilis MA-4680 1210840 NP_825066.1 CDS SAV_3889 NC_003155.4 4804428 4805537 D hypothetical protein 4804428..4805537 Streptomyces avermitilis MA-4680 1214840 NP_825067.1 CDS SAV_3890 NC_003155.4 4805796 4806788 R PF00248: Aldo/keto reductase family; NDP-4-keto-6-deoxy-L-hexose 2,3-reductase complement(4805796..4806788) Streptomyces avermitilis MA-4680 1214841 NP_825068.1 CDS SAV_3891 NC_003155.4 4806853 4807905 R PF00107: Zinc-binding dehydrogenase; quinone oxidoreductase complement(4806853..4807905) Streptomyces avermitilis MA-4680 1214842 NP_825069.1 CDS SAV_3892 NC_003155.4 4808237 4808809 R PF02834: 2',5' RNA ligase family; hypothetical protein complement(4808237..4808809) Streptomyces avermitilis MA-4680 1214843 NP_825070.1 CDS SAV_3893 NC_003155.4 4808855 4809367 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 4808855..4809367 Streptomyces avermitilis MA-4680 1214844 NP_825071.1 CDS SAV_3894 NC_003155.4 4809411 4810757 R PF07690: Major Facilitator Superfamily; integral membrane efflux protein complement(4809411..4810757) Streptomyces avermitilis MA-4680 1214845 NP_825072.1 CDS SAV_3895 NC_003155.4 4810885 4811322 R MarR family transcriptional regulator complement(4810885..4811322) Streptomyces avermitilis MA-4680 1214846 NP_825073.1 CDS SAV_3896 NC_003155.4 4811516 4811698 D hypothetical protein 4811516..4811698 Streptomyces avermitilis MA-4680 1214847 NP_825074.1 CDS SAV_3897 NC_003155.4 4811717 4813168 R PF00860: Permease family; permease complement(4811717..4813168) Streptomyces avermitilis MA-4680 1214848 NP_825075.1 CDS SAV_3898 NC_003155.4 4813428 4813694 D integral membrane protein 4813428..4813694 Streptomyces avermitilis MA-4680 1214849 NP_825076.1 CDS ctpE NC_003155.4 4813851 4816244 D PF00122: E1-E2 ATPase; integral membrane ATPase 4813851..4816244 Streptomyces avermitilis MA-4680 1214850 NP_825077.1 CDS SAV_3900 NC_003155.4 4816257 4817168 R hypothetical protein complement(4816257..4817168) Streptomyces avermitilis MA-4680 1214851 NP_825078.1 CDS SAV_3901 NC_003155.4 4817419 4820703 R hypothetical protein complement(4817419..4820703) Streptomyces avermitilis MA-4680 1214852 NP_825079.1 CDS SAV_3902 NC_003155.4 4821179 4822105 R hypothetical protein complement(4821179..4822105) Streptomyces avermitilis MA-4680 1214853 NP_825080.1 CDS SAV_3903 NC_003155.4 4822801 4824225 D PF07690: Major Facilitator Superfamily; integral membrane protein 4822801..4824225 Streptomyces avermitilis MA-4680 1214854 NP_825081.1 CDS SAV_3904 NC_003155.4 4824479 4824937 D lipoprotein 4824479..4824937 Streptomyces avermitilis MA-4680 1214855 NP_825082.1 CDS SAV_3905 NC_003155.4 4824994 4825665 D PF01048: Phosphorylase family; hypothetical protein 4824994..4825665 Streptomyces avermitilis MA-4680 1214856 NP_825083.1 CDS SAV_3906 NC_003155.4 4825655 4826509 D PF02642: Uncharacterized ACR, COG2107; hypothetical protein 4825655..4826509 Streptomyces avermitilis MA-4680 1214857 NP_825084.1 CDS cspB1 NC_003155.4 4826562 4826945 R cold shock protein complement(4826562..4826945) Streptomyces avermitilis MA-4680 1210841 NP_825085.1 CDS SAV_3908 NC_003155.4 4827361 4827990 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(4827361..4827990) Streptomyces avermitilis MA-4680 1214858 NP_825086.1 CDS SAV_3909 NC_003155.4 4828326 4828865 R hypothetical protein complement(4828326..4828865) Streptomyces avermitilis MA-4680 1214859 NP_825087.1 CDS SAV_3910 NC_003155.4 4829201 4829344 D hypothetical protein 4829201..4829344 Streptomyces avermitilis MA-4680 1214860 NP_825088.1 CDS SAV_3911 NC_003155.4 4829509 4832091 D hypothetical protein 4829509..4832091 Streptomyces avermitilis MA-4680 1214861 NP_825089.1 CDS SAV_3912 NC_003155.4 4832156 4833799 D ATP-dependent DNA helicase 4832156..4833799 Streptomyces avermitilis MA-4680 1214862 NP_825090.1 CDS SAV_3913 NC_003155.4 4833757 4834953 R hypothetical protein complement(4833757..4834953) Streptomyces avermitilis MA-4680 1214863 NP_825091.1 CDS SAV_3914 NC_003155.4 4835338 4835589 R hypothetical protein complement(4835338..4835589) Streptomyces avermitilis MA-4680 1214864 NP_825092.1 CDS helD NC_003155.4 4835900 4837948 D ATP-dependent DNA helicase 4835900..4837948 Streptomyces avermitilis MA-4680 1210842 NP_825093.1 CDS SAV_3916 NC_003155.4 4838061 4839290 R protein complement(4838061..4839290) Streptomyces avermitilis MA-4680 1214865 NP_825094.1 CDS SAV_3917 NC_003155.4 4839478 4840176 R homeostasis protein complement(4839478..4840176) Streptomyces avermitilis MA-4680 1214866 NP_825095.1 CDS SAV_3918 NC_003155.4 4840365 4841042 R hypothetical protein complement(4840365..4841042) Streptomyces avermitilis MA-4680 1214867 NP_825096.1 CDS SAV_3919 NC_003155.4 4841081 4841758 D PF01966: HD domain; hypothetical protein 4841081..4841758 Streptomyces avermitilis MA-4680 1214868 NP_825097.1 CDS SAV_3920 NC_003155.4 4841782 4842768 D PF00494: Squalene/phytoene synthase; phytoene synthase 4841782..4842768 Streptomyces avermitilis MA-4680 1214869 NP_825098.1 CDS SAV_3921 NC_003155.4 4842758 4843042 R hypothetical protein complement(4842758..4843042) Streptomyces avermitilis MA-4680 1214870 NP_825099.1 CDS SAV_3922 NC_003155.4 4843039 4843422 R hypothetical protein complement(4843039..4843422) Streptomyces avermitilis MA-4680 1214871 NP_825100.1 CDS SAV_3923 NC_003155.4 4843479 4844405 D transcriptional regulator 4843479..4844405 Streptomyces avermitilis MA-4680 1214872 NP_825101.1 CDS murQ NC_003155.4 4844522 4845457 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 4844522..4845457 Streptomyces avermitilis MA-4680 1214873 NP_825102.1 CDS scrA NC_003155.4 4845474 4847111 D PF02378: phosphotransferase system EIIC, PF00367: phosphotransferase system EIIB; PTS sucrose-specific enzyme IIBC component 4845474..4847111 Streptomyces avermitilis MA-4680 1214874 NP_825103.1 CDS SAV_3926 NC_003155.4 4847108 4847695 D hypothetical protein 4847108..4847695 Streptomyces avermitilis MA-4680 1214875 NP_825104.1 CDS SAV_3927 NC_003155.4 4847846 4848223 D PF01740: STAS domain; anti-sigma factor antagonist 4847846..4848223 Streptomyces avermitilis MA-4680 1214876 NP_825105.1 CDS prpJ6 NC_003155.4 4848241 4849965 D PF00989: PAS domain; magnesium or manganese-dependent protein phosphatase 4848241..4849965 Streptomyces avermitilis MA-4680 1214877 NP_825106.1 CDS SAV_3929 NC_003155.4 4850060 4851187 R PF00724: NADH:flavin oxidoreductase / NADH oxidase family; oxidoreductase complement(4850060..4851187) Streptomyces avermitilis MA-4680 1214878 NP_825107.1 CDS SAV_3930 NC_003155.4 4851499 4854066 D hypothetical protein 4851499..4854066 Streptomyces avermitilis MA-4680 1214879 NP_825108.1 CDS groEL NC_003155.4 4854193 4855818 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(4854193..4855818) Streptomyces avermitilis MA-4680 1210843 NP_825109.1 CDS cspB2 NC_003155.4 4856153 4856359 R cold shock protein complement(4856153..4856359) Streptomyces avermitilis MA-4680 1210844 NP_825110.1 CDS SAV_3933 NC_003155.4 4856813 4857088 R PF02597: ThiS family; hypothetical protein complement(4856813..4857088) Streptomyces avermitilis MA-4680 1214880 NP_825111.1 CDS thrC3 NC_003155.4 4857164 4858462 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(4857164..4858462) Streptomyces avermitilis MA-4680 1210845 NP_825112.1 CDS SAV_3935 NC_003155.4 4858803 4859747 D PF00535: Glycosyl transferase; putative glucosyl-3-phosphoglycerate synthase 4858803..4859747 Streptomyces avermitilis MA-4680 1214881 NP_825113.1 CDS otsA NC_003155.4 4859857 4861248 D trehalose-6-phosphate synthase 4859857..4861248 Streptomyces avermitilis MA-4680 1214882 NP_825114.1 CDS otsB NC_003155.4 4861292 4862155 R trehalose-6-phosphatase complement(4861292..4862155) Streptomyces avermitilis MA-4680 1214883 NP_825115.1 CDS SAV_3938 NC_003155.4 4862257 4862502 R hypothetical protein complement(4862257..4862502) Streptomyces avermitilis MA-4680 1214884 NP_825116.1 CDS SAV_3939 NC_003155.4 4862584 4863861 R ABC transporter substrate-binding protein complement(4862584..4863861) Streptomyces avermitilis MA-4680 1214885 NP_825117.1 CDS SAV_3940 NC_003155.4 4864012 4864917 D transcriptional regulator 4864012..4864917 Streptomyces avermitilis MA-4680 1214886 NP_825118.1 CDS nagA NC_003155.4 4864917 4866062 D N-acetylglucosamine-6-phosphate deacetylase 4864917..4866062 Streptomyces avermitilis MA-4680 1210846 NP_825119.1 CDS SAV_3942 NC_003155.4 4866207 4867136 D sugar kinase 4866207..4867136 Streptomyces avermitilis MA-4680 1214887 NP_825120.1 CDS SAV_3943 NC_003155.4 4867210 4868160 R dimeric protein complement(4867210..4868160) Streptomyces avermitilis MA-4680 1214888 NP_825121.1 CDS SAV_3944 NC_003155.4 4868278 4869984 R PF00990: GGDEF domain; hypothetical protein complement(4868278..4869984) Streptomyces avermitilis MA-4680 1214889 NP_825122.1 CDS thiX2 NC_003155.4 4870392 4870970 D flavin-dependent reductase 4870392..4870970 Streptomyces avermitilis MA-4680 1214890 NP_825123.1 CDS SAV_3946 NC_003155.4 4871149 4871577 R PF00472: Peptidyl-tRNA hydrolase domain; peptidyl-tRNA hydrolase domain protein complement(4871149..4871577) Streptomyces avermitilis MA-4680 1214891 NP_825124.1 CDS terD2 NC_003155.4 4871772 4872347 D PF02342: Bacterial stress protein; tellurium resistance protein 4871772..4872347 Streptomyces avermitilis MA-4680 1214892 NP_825125.1 CDS SAV_3948 NC_003155.4 4872707 4873561 R DNA-binding protein complement(4872707..4873561) Streptomyces avermitilis MA-4680 1214893 NP_825126.1 CDS SAV_3949 NC_003155.4 4873781 4874197 D regulatory protein 4873781..4874197 Streptomyces avermitilis MA-4680 1214894 NP_825127.1 CDS SAV_3950 NC_003155.4 4874208 4875164 D mutT-like protein 4874208..4875164 Streptomyces avermitilis MA-4680 1214895 NP_825128.2 CDS SAV_3951 NC_003155.4 4875231 4876352 D IS630 family transposase 4875231..4876352 Streptomyces avermitilis MA-4680 1214896 NP_825129.1 CDS SAV_3952 NC_003155.4 4876393 4877802 R PF01433: Peptidase family M1; metallopeptidase complement(4876393..4877802) Streptomyces avermitilis MA-4680 1214897 NP_825130.1 CDS SAV_3953 NC_003155.4 4877882 4878382 D hypothetical protein 4877882..4878382 Streptomyces avermitilis MA-4680 1214898 NP_825131.1 CDS SAV_3954 NC_003155.4 4878430 4879224 R PF00805: Pentapeptide repeats (8 copies); hypothetical protein complement(4878430..4879224) Streptomyces avermitilis MA-4680 1214899 NP_825132.1 CDS SAV_3955 NC_003155.4 4879303 4880472 D PF01593: Flavin containing amine oxidoreductase; hypothetical protein 4879303..4880472 Streptomyces avermitilis MA-4680 1214900 NP_825133.1 CDS SAV_3956 NC_003155.4 4880526 4881515 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 4880526..4881515 Streptomyces avermitilis MA-4680 1214901 NP_825134.1 CDS SAV_3957 NC_003155.4 4881639 4883138 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 4881639..4883138 Streptomyces avermitilis MA-4680 1214902 NP_825135.1 CDS SAV_3958 NC_003155.4 4883217 4883690 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(4883217..4883690) Streptomyces avermitilis MA-4680 1214903 NP_825136.1 CDS SAV_3959 NC_003155.4 4883778 4885193 R PF01266: FAD dependent oxidoreductase; hypothetical protein complement(4883778..4885193) Streptomyces avermitilis MA-4680 1214904 NP_825137.1 CDS SAV_3960 NC_003155.4 4885204 4885794 R hypothetical protein complement(4885204..4885794) Streptomyces avermitilis MA-4680 1214905 NP_825138.1 CDS hur NC_003155.4 4885883 4886776 D hydroxyurea resistance protein, PF04655: Aminoglycoside/hydroxyurea antibiotic resistance kinase; hydroxyurea phosphotransferase 4885883..4886776 Streptomyces avermitilis MA-4680 1210847 NP_825139.1 CDS msiK NC_003155.4 4887143 4888279 D ABC transporter ATP-binding protein 4887143..4888279 Streptomyces avermitilis MA-4680 1210849 NP_825140.1 CDS SAV_3963 NC_003155.4 4888508 4888966 D hypothetical protein 4888508..4888966 Streptomyces avermitilis MA-4680 1214906 NP_825141.1 CDS SAV_3964 NC_003155.4 4889067 4889798 D PF00483: Nucleotidyl transferase; guanyltransferase 4889067..4889798 Streptomyces avermitilis MA-4680 1214907 NP_825142.1 CDS SAV_3965 NC_003155.4 4889986 4891683 R PF07681: DoxX; integral membrane protein complement(4889986..4891683) Streptomyces avermitilis MA-4680 1214908 NP_825143.1 CDS SAV_3966 NC_003155.4 4891822 4892763 R PF00588: SpoU rRNA Methylase family; tRNA/rRNA methyltransferase complement(4891822..4892763) Streptomyces avermitilis MA-4680 1214909 NP_825144.1 CDS cysS NC_003155.4 4892866 4894266 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(4892866..4894266) Streptomyces avermitilis MA-4680 1210850 NP_825145.1 CDS ispF NC_003155.4 4894477 4895001 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(4894477..4895001) Streptomyces avermitilis MA-4680 1210851 NP_825146.1 CDS ispD NC_003155.4 4894991 4895743 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(4894991..4895743) Streptomyces avermitilis MA-4680 1210852 NP_825147.1 CDS SAV_3970 NC_003155.4 4896097 4896579 R CarD-like transcriptional regulator complement(4896097..4896579) Streptomyces avermitilis MA-4680 1214910 NP_825148.1 CDS SAV_3971 NC_003155.4 4897210 4897872 D PF04314: Protein of unknown function (DUF461); lipoprotein 4897210..4897872 Streptomyces avermitilis MA-4680 1214911 NP_825149.1 CDS phoP NC_003155.4 4898071 4898742 R two-component system response regulator complement(4898071..4898742) Streptomyces avermitilis MA-4680 1214912 NP_825150.1 CDS phoR NC_003155.4 4898748 4900025 R two-component system sensor kinase complement(4898748..4900025) Streptomyces avermitilis MA-4680 1214913 NP_825151.1 CDS phoU NC_003155.4 4900250 4900939 D phosphate transport system regulatory protein 4900250..4900939 Streptomyces avermitilis MA-4680 1210853 NP_825152.1 CDS SAV_3975 NC_003155.4 4901155 4901307 R hypothetical protein complement(4901155..4901307) Streptomyces avermitilis MA-4680 1214914 NP_825153.1 CDS SAV_3976 NC_003155.4 4901452 4902474 R PF00248: Aldo/keto reductase family; oxidoreductase complement(4901452..4902474) Streptomyces avermitilis MA-4680 1214915 NP_825154.1 CDS SAV_3977 NC_003155.4 4902641 4903567 D AraC family transcription regulator 4902641..4903567 Streptomyces avermitilis MA-4680 1214916 NP_825155.1 CDS SAV_3978 NC_003155.4 4903668 4904975 R PF07690: Major Facilitator Superfamily; integral membrane transport protein complement(4903668..4904975) Streptomyces avermitilis MA-4680 1214917 NP_825156.1 CDS gpmA NC_003155.4 4905162 4905923 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 4905162..4905923 Streptomyces avermitilis MA-4680 1210854 NP_825157.1 CDS int9 NC_003155.4 4906639 4907955 R PF00589: Phage integrase family; phage-related integrase complement(4906639..4907955) Streptomyces avermitilis MA-4680 1214918 NP_825158.1 CDS SAV_3981 NC_003155.4 4907955 4908194 R hypothetical protein complement(4907955..4908194) Streptomyces avermitilis MA-4680 1214919 NP_825159.1 CDS repSA2 NC_003155.4 4908187 4909554 R replication initiation protein complement(4908187..4909554) Streptomyces avermitilis MA-4680 1210855 NP_825160.1 CDS spdD2 NC_003155.4 4909627 4909908 R SpdD protein complement(4909627..4909908) Streptomyces avermitilis MA-4680 1210856 NP_825161.1 CDS SAV_3984 NC_003155.4 4909901 4910095 R hypothetical protein complement(4909901..4910095) Streptomyces avermitilis MA-4680 1214920 NP_825162.1 CDS spdB2 NC_003155.4 4910112 4910303 R mobile element transfer protein SpdB complement(4910112..4910303) Streptomyces avermitilis MA-4680 1210857 NP_825163.1 CDS spdA2 NC_003155.4 4910315 4910944 R mobile element transfer protein SpdA complement(4910315..4910944) Streptomyces avermitilis MA-4680 1210858 NP_825164.1 CDS traSA2 NC_003155.4 4911150 4912445 R plasmid transfer protein complement(4911150..4912445) Streptomyces avermitilis MA-4680 1210859 NP_825165.1 CDS pra2 NC_003155.4 4912445 4912801 R replication activator protein Pra complement(4912445..4912801) Streptomyces avermitilis MA-4680 1210860 NP_825166.1 CDS korSA2 NC_003155.4 4912971 4913759 R PF07702: UbiC transcription regulator-associated; regulatory protein KorSA complement(4912971..4913759) Streptomyces avermitilis MA-4680 1210861 NP_825167.1 CDS SAV_3990 NC_003155.4 4913786 4914274 D MutT-like protein 4913786..4914274 Streptomyces avermitilis MA-4680 1214921 NP_825168.1 CDS SAV_3991 NC_003155.4 4914291 4914755 D regulatory protein 4914291..4914755 Streptomyces avermitilis MA-4680 1214922 NP_825169.1 CDS SAV_3992 NC_003155.4 4914749 4915141 D hypothetical protein 4914749..4915141 Streptomyces avermitilis MA-4680 1214923 NP_825170.1 CDS SAV_3993 NC_003155.4 4915182 4915616 R hypothetical protein complement(4915182..4915616) Streptomyces avermitilis MA-4680 1214924 NP_825171.1 CDS pkn8 NC_003155.4 4915779 4916903 D serine/threonine protein kinase 4915779..4916903 Streptomyces avermitilis MA-4680 1210862 NP_825172.1 CDS SAV_3995 NC_003155.4 4916980 4917876 D hypothetical protein 4916980..4917876 Streptomyces avermitilis MA-4680 1214925 NP_825173.1 CDS SAV_3996 NC_003155.4 4918085 4918567 D hypothetical protein 4918085..4918567 Streptomyces avermitilis MA-4680 1214926 NP_825174.1 CDS SAV_3997 NC_003155.4 4918858 4919292 R PF07366: Protein of unknown function (DUF1486); hypothetical protein complement(4918858..4919292) Streptomyces avermitilis MA-4680 1214927 NP_825175.1 CDS SAV_3998 NC_003155.4 4919565 4920089 D hypothetical protein 4919565..4920089 Streptomyces avermitilis MA-4680 1214928 NP_825176.1 CDS SAV_3999 NC_003155.4 4920086 4921093 D hypothetical protein 4920086..4921093 Streptomyces avermitilis MA-4680 1214929 NP_825177.1 CDS SAV_4000 NC_003155.4 4921426 4921935 D hypothetical protein 4921426..4921935 Streptomyces avermitilis MA-4680 1214930 NP_825178.1 CDS SAV_4001 NC_003155.4 4921900 4922481 R hypothetical protein complement(4921900..4922481) Streptomyces avermitilis MA-4680 1214931 NP_825179.1 CDS SAV_4002 NC_003155.4 4922628 4922972 R hypothetical protein complement(4922628..4922972) Streptomyces avermitilis MA-4680 1214932 NP_825180.1 CDS SAV_4003 NC_003155.4 4923144 4923956 D AraC family transcription regulator 4923144..4923956 Streptomyces avermitilis MA-4680 1214933 NP_825181.1 CDS SAV_4004 NC_003155.4 4923935 4925701 R hypothetical protein complement(4923935..4925701) Streptomyces avermitilis MA-4680 1214934 NP_825182.1 CDS SAV_4005 NC_003155.4 4925852 4926343 R hypothetical protein complement(4925852..4926343) Streptomyces avermitilis MA-4680 1214935 NP_825183.1 CDS glgA1 NC_003155.4 4926336 4927730 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(4926336..4927730) Streptomyces avermitilis MA-4680 1214936 NP_825184.1 CDS SAV_4007 NC_003155.4 4927874 4928692 D hypothetical protein 4927874..4928692 Streptomyces avermitilis MA-4680 1214937 NP_825185.1 CDS SAV_4008 NC_003155.4 4928935 4930026 D Seems to have a cleavable N-term signal sequence; NLP/P60-family protein 4928935..4930026 Streptomyces avermitilis MA-4680 1214938 NP_825186.1 CDS prpG1 NC_003155.4 4930332 4931780 D PF00072: Response regulator receiver domain; magnesium or manganese-dependent protein phosphatase 4930332..4931780 Streptomyces avermitilis MA-4680 1214939 NP_825187.1 CDS SAV_4010 NC_003155.4 4931839 4932180 R hypothetical protein complement(4931839..4932180) Streptomyces avermitilis MA-4680 1214940 NP_825188.1 CDS SAV_4011 NC_003155.4 4932294 4932896 R PF05558: DREPP plasma membrane polypeptide; hypothetical protein complement(4932294..4932896) Streptomyces avermitilis MA-4680 1214941 NP_825189.1 CDS SAV_4012 NC_003155.4 4932975 4933451 R DNA-binding protein complement(4932975..4933451) Streptomyces avermitilis MA-4680 1214942 NP_825190.1 CDS SAV_4013 NC_003155.4 4933625 4934038 D integral membrane protein 4933625..4934038 Streptomyces avermitilis MA-4680 1214943 NP_825191.1 CDS SAV_4014 NC_003155.4 4934070 4935080 R PF00724: NADH:flavin oxidoreductase / NADH oxidase family; oxidoreductase complement(4934070..4935080) Streptomyces avermitilis MA-4680 1214944 NP_825192.1 CDS SAV_4015 NC_003155.4 4935246 4935623 D MerR family transcriptional regulator 4935246..4935623 Streptomyces avermitilis MA-4680 1214945 NP_825193.1 CDS SAV_4016 NC_003155.4 4935669 4937714 R ATP/GTP-binding protein complement(4935669..4937714) Streptomyces avermitilis MA-4680 1214946 NP_825194.1 CDS SAV_4017 NC_003155.4 4937841 4938455 R TetR family transcriptional regulator complement(4937841..4938455) Streptomyces avermitilis MA-4680 1214947 NP_825195.1 CDS SAV_4018 NC_003155.4 4938560 4939528 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 4938560..4939528 Streptomyces avermitilis MA-4680 1214948 NP_825196.1 CDS SAV_4019 NC_003155.4 4939587 4941824 R PF01636: Phosphotransferase enzyme family; hypothetical protein complement(4939587..4941824) Streptomyces avermitilis MA-4680 1214949 NP_825197.1 CDS SAV_4020 NC_003155.4 4942087 4942890 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(4942087..4942890) Streptomyces avermitilis MA-4680 1214950 NP_825198.1 CDS SAV_4021 NC_003155.4 4942839 4943717 R GntR family transcriptional regulator complement(4942839..4943717) Streptomyces avermitilis MA-4680 1214951 NP_825199.1 CDS SAV_4022 NC_003155.4 4943871 4944059 D hypothetical protein 4943871..4944059 Streptomyces avermitilis MA-4680 1214952 NP_825200.1 CDS SAV_4023 NC_003155.4 4944066 4944983 R GntR family transcriptional regulator complement(4944066..4944983) Streptomyces avermitilis MA-4680 1214953 NP_825201.1 CDS SAV_4024 NC_003155.4 4945345 4946601 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(4945345..4946601) Streptomyces avermitilis MA-4680 1214954 NP_825202.1 CDS SAV_4025 NC_003155.4 4946725 4947714 R L-asparaginase II complement(4946725..4947714) Streptomyces avermitilis MA-4680 1214955 NP_825203.1 CDS amfC NC_003155.4 4947905 4948501 R AmfC protein complement(4947905..4948501) Streptomyces avermitilis MA-4680 1210863 NP_825204.1 CDS SAV_4027 NC_003155.4 4948672 4949109 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4948672..4949109 Streptomyces avermitilis MA-4680 1214956 NP_825205.1 CDS SAV_4028 NC_003155.4 4949159 4950124 R PF01571: Glycine cleavage T-protein (aminomethyl transferase); hypothetical protein complement(4949159..4950124) Streptomyces avermitilis MA-4680 1214957 NP_825206.1 CDS SAV_4029 NC_003155.4 4950135 4950572 R iron uptake regulatory protein complement(4950135..4950572) Streptomyces avermitilis MA-4680 1214958 NP_825207.1 CDS SAV_4030 NC_003155.4 4950649 4951224 R hypothetical protein complement(4950649..4951224) Streptomyces avermitilis MA-4680 1214959 NP_825208.1 CDS SAV_4031 NC_003155.4 4951514 4952359 R hypothetical protein complement(4951514..4952359) Streptomyces avermitilis MA-4680 1214960 NP_825209.1 CDS SAV_4032 NC_003155.4 4952356 4953147 R hypothetical protein complement(4952356..4953147) Streptomyces avermitilis MA-4680 1214961 NP_825210.1 CDS SAV_4033 NC_003155.4 4953222 4954115 R hypothetical protein complement(4953222..4954115) Streptomyces avermitilis MA-4680 1214962 NP_825211.1 CDS SAV_4034 NC_003155.4 4954208 4954555 D PF02635: DsrE/DsrF-like family; hypothetical protein 4954208..4954555 Streptomyces avermitilis MA-4680 1214963 NP_825212.1 CDS SAV_4035 NC_003155.4 4954885 4955196 R hypothetical protein complement(4954885..4955196) Streptomyces avermitilis MA-4680 1214964 NP_825213.1 CDS SAV_4036 NC_003155.4 4955234 4955521 R PF07210: Protein of unknown function (DUF1416); hypothetical protein complement(4955234..4955521) Streptomyces avermitilis MA-4680 1214965 NP_825214.1 CDS cysA2 NC_003155.4 4955552 4956391 R thiosulfate sulfurtransferase complement(4955552..4956391) Streptomyces avermitilis MA-4680 1210864 NP_825215.1 CDS SAV_4038 NC_003155.4 4956838 4957581 R hypothetical protein complement(4956838..4957581) Streptomyces avermitilis MA-4680 1214966 NP_825216.1 CDS SAV_4039 NC_003155.4 4957811 4959025 R integral membrane protein complement(4957811..4959025) Streptomyces avermitilis MA-4680 1214967 NP_825217.1 CDS moaD NC_003155.4 4959022 4959276 R molybdopterin converting factor complement(4959022..4959276) Streptomyces avermitilis MA-4680 1210865 NP_825218.1 CDS SAV_4041 NC_003155.4 4959369 4960262 R PF00326: Prolyl oligopeptidase family; hydrolase complement(4959369..4960262) Streptomyces avermitilis MA-4680 1214968 NP_825219.1 CDS SAV_4042 NC_003155.4 4960555 4961364 D two-component system response regulator 4960555..4961364 Streptomyces avermitilis MA-4680 1214969 NP_825220.1 CDS SAV_4043 NC_003155.4 4961428 4962471 D LacI family transcriptional regulator 4961428..4962471 Streptomyces avermitilis MA-4680 1214970 NP_825221.1 CDS SAV_4044 NC_003155.4 4962728 4964491 R PF00089: Trypsin; trypsin-like protease complement(4962728..4964491) Streptomyces avermitilis MA-4680 1214971 NP_825222.1 CDS SAV_4045 NC_003155.4 4964900 4966135 D PF00089: Trypsin; serine protease 4964900..4966135 Streptomyces avermitilis MA-4680 1214972 NP_825223.1 CDS SAV_4046 NC_003155.4 4966152 4966406 D hypothetical protein 4966152..4966406 Streptomyces avermitilis MA-4680 1214973 NP_825224.1 CDS SAV_4047 NC_003155.4 4966793 4967524 D two-component system response regulator 4966793..4967524 Streptomyces avermitilis MA-4680 1214974 NP_825225.1 CDS SAV_4048 NC_003155.4 4967521 4969005 D two-component system sensor kinase 4967521..4969005 Streptomyces avermitilis MA-4680 1214975 NP_825226.1 CDS SAV_4049 NC_003155.4 4969010 4969225 R regulatory protein complement(4969010..4969225) Streptomyces avermitilis MA-4680 1214976 NP_825227.1 CDS SAV_4050 NC_003155.4 4969213 4970046 R DNA-binding protein complement(4969213..4970046) Streptomyces avermitilis MA-4680 1214977 NP_825228.1 CDS SAV_4051 NC_003155.4 4970507 4970803 D hypothetical protein 4970507..4970803 Streptomyces avermitilis MA-4680 1214978 NP_825229.1 CDS SAV_4052 NC_003155.4 4970862 4972535 R PF03023: MviN-like protein; hypothetical protein complement(4970862..4972535) Streptomyces avermitilis MA-4680 1214979 NP_825230.1 CDS SAV_4053 NC_003155.4 4972612 4974417 R ABC transporter ATP-binding protein complement(4972612..4974417) Streptomyces avermitilis MA-4680 1214980 NP_825231.1 CDS SAV_4054 NC_003155.4 4974504 4974677 D hypothetical protein 4974504..4974677 Streptomyces avermitilis MA-4680 1214981 NP_825232.1 CDS SAV_4055 NC_003155.4 4974733 4974867 R hypothetical protein complement(4974733..4974867) Streptomyces avermitilis MA-4680 1214982 NP_825233.1 CDS SAV_4056 NC_003155.4 4975110 4976189 R hypothetical protein complement(4975110..4976189) Streptomyces avermitilis MA-4680 1214983 NP_825234.1 CDS SAV_4057 NC_003155.4 4976461 4978272 R 5'-nucleotidase complement(4976461..4978272) Streptomyces avermitilis MA-4680 1214984 NP_825235.1 CDS mshD NC_003155.4 4978424 4979350 D mycothiol biosynthesis; acetyltransferase 4978424..4979350 Streptomyces avermitilis MA-4680 1214985 NP_825236.1 CDS SAV_4059 NC_003155.4 4979424 4980002 R hypothetical protein complement(4979424..4980002) Streptomyces avermitilis MA-4680 1214986 NP_825237.1 CDS SAV_4060 NC_003155.4 4980098 4981669 R hypothetical protein complement(4980098..4981669) Streptomyces avermitilis MA-4680 1214987 NP_825238.1 CDS SAV_4061 NC_003155.4 4981666 4982532 R ABC transporter ATP-binding protein complement(4981666..4982532) Streptomyces avermitilis MA-4680 1214988 NP_825239.1 CDS SAV_4062 NC_003155.4 4982624 4982830 R hypothetical protein complement(4982624..4982830) Streptomyces avermitilis MA-4680 1214989 NP_825240.1 CDS SAV_4063 NC_003155.4 4982830 4983687 R integral membrane protein complement(4982830..4983687) Streptomyces avermitilis MA-4680 1214990 NP_825241.1 CDS sig33 NC_003155.4 4983684 4984223 R ECF subfamily RNA polymerase sigma factor complement(4983684..4984223) Streptomyces avermitilis MA-4680 1210866 NP_825242.1 CDS SAV_4065 NC_003155.4 4984323 4984721 D GntR family transcriptional regulator 4984323..4984721 Streptomyces avermitilis MA-4680 1214991 NP_825243.1 CDS SAV_4066 NC_003155.4 4984718 4985635 D ABC transporter ATP-binding protein 4984718..4985635 Streptomyces avermitilis MA-4680 1214992 NP_825244.1 CDS SAV_4067 NC_003155.4 4985632 4986573 D hypothetical protein 4985632..4986573 Streptomyces avermitilis MA-4680 1214993 NP_825245.1 CDS SAV_4068 NC_003155.4 4986585 4987538 D hypothetical protein 4986585..4987538 Streptomyces avermitilis MA-4680 1214994 NP_825246.1 CDS ppk NC_003155.4 4987758 4990112 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 4987758..4990112 Streptomyces avermitilis MA-4680 1210867 NP_825247.1 CDS SAV_4070 NC_003155.4 4990093 4991175 D hypothetical protein 4990093..4991175 Streptomyces avermitilis MA-4680 1214995 NP_825248.1 CDS SAV_4071 NC_003155.4 4991242 4991655 D PF00293: NUDIX domain; hypothetical protein 4991242..4991655 Streptomyces avermitilis MA-4680 1214996 NP_825249.1 CDS pstS NC_003155.4 4991906 4993012 D phosphate-binding protein precursor 4991906..4993012 Streptomyces avermitilis MA-4680 1210868 NP_825250.1 CDS pstC NC_003155.4 4993113 4994120 D PF00528: Binding-protein-dependent transport system inner membrane component; phosphate ABC transporter permease 4993113..4994120 Streptomyces avermitilis MA-4680 1210869 NP_825251.1 CDS pstA NC_003155.4 4994117 4995178 D phosphate ABC transporter permease 4994117..4995178 Streptomyces avermitilis MA-4680 1210870 NP_825252.1 CDS pstB NC_003155.4 4995253 4996029 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4995253..4996029 Streptomyces avermitilis MA-4680 1210871 NP_825253.1 CDS pitH1 NC_003155.4 4996433 4997431 R low-affinity inorganic phosphate transporter complement(4996433..4997431) Streptomyces avermitilis MA-4680 1210872 NP_825254.1 CDS SAV_4077 NC_003155.4 4997439 4998059 R Pit accessory protein complement(4997439..4998059) Streptomyces avermitilis MA-4680 1214997 NP_825255.1 CDS SAV_4078 NC_003155.4 4998272 4998628 D PF02583: Uncharacterised BCR, COG1937; hypothetical protein 4998272..4998628 Streptomyces avermitilis MA-4680 1214998 NP_825256.1 CDS SAV_4079 NC_003155.4 4998730 4998918 R hypothetical protein complement(4998730..4998918) Streptomyces avermitilis MA-4680 1214999 NP_825257.1 CDS SAV_4080 NC_003155.4 4999070 4999903 R lipoprotein complement(4999070..4999903) Streptomyces avermitilis MA-4680 1215000 NP_825258.1 CDS SAV_4081 NC_003155.4 5000470 5002047 D PF01565: FAD binding domain; lipoprotein 5000470..5002047 Streptomyces avermitilis MA-4680 1215001 NP_825259.1 CDS SAV_4082 NC_003155.4 5002135 5002833 R PF01569: PAP2 superfamily; integral membrane protein complement(5002135..5002833) Streptomyces avermitilis MA-4680 1215002 NP_825260.1 CDS SAV_4083 NC_003155.4 5003027 5004034 R PF00877: NlpC/P60 family; transglycosylase complement(5003027..5004034) Streptomyces avermitilis MA-4680 1215003 NP_825261.1 CDS pkn9 NC_003155.4 5004166 5005890 R serine/threonine protein kinase complement(5004166..5005890) Streptomyces avermitilis MA-4680 1210873 NP_825262.1 CDS SAV_4085 NC_003155.4 5005913 5006737 R PF00089: Trypsin; hypothetical protein complement(5005913..5006737) Streptomyces avermitilis MA-4680 1215004 NP_825263.1 CDS SAV_4086 NC_003155.4 5006750 5007181 R regulatory protein complement(5006750..5007181) Streptomyces avermitilis MA-4680 1215005 NP_825264.1 CDS SAV_4087 NC_003155.4 5007367 5008239 D DNA-binding protein 5007367..5008239 Streptomyces avermitilis MA-4680 1215006 NP_825265.1 CDS SAV_4088 NC_003155.4 5008236 5008451 D PF04149: Domain of unknown function (DUF397); hypothetical protein 5008236..5008451 Streptomyces avermitilis MA-4680 1215007 NP_825266.1 CDS SAV_4089 NC_003155.4 5008444 5008689 D PF04149: Domain of unknown function (DUF397); hypothetical protein 5008444..5008689 Streptomyces avermitilis MA-4680 1215008 NP_825267.1 CDS SAV_4090 NC_003155.4 5008711 5009085 R hypothetical protein complement(5008711..5009085) Streptomyces avermitilis MA-4680 1215009 NP_825268.1 CDS SAV_4091 NC_003155.4 5009394 5009873 R hypothetical protein complement(5009394..5009873) Streptomyces avermitilis MA-4680 1215010 NP_825269.1 CDS SAV_4092 NC_003155.4 5009903 5010520 R PF00805: Pentapeptide repeats (8 copies); hypothetical protein complement(5009903..5010520) Streptomyces avermitilis MA-4680 1215011 NP_825270.1 CDS SAV_4093 NC_003155.4 5010521 5011432 R hypothetical protein complement(5010521..5011432) Streptomyces avermitilis MA-4680 1215012 NP_825271.1 CDS SAV_4094 NC_003155.4 5011670 5013994 R hypothetical protein complement(5011670..5013994) Streptomyces avermitilis MA-4680 1215013 NP_825272.1 CDS SAV_4095 NC_003155.4 5013991 5014383 R hypothetical protein complement(5013991..5014383) Streptomyces avermitilis MA-4680 1215014 NP_825273.1 CDS SAV_4096 NC_003155.4 5014424 5014741 R hypothetical protein complement(5014424..5014741) Streptomyces avermitilis MA-4680 1215015 NP_825274.1 CDS SAV_4097 NC_003155.4 5014792 5015124 R hypothetical protein complement(5014792..5015124) Streptomyces avermitilis MA-4680 1215016 NP_825275.1 CDS SAV_4098 NC_003155.4 5015883 5016191 D integral membrane protein 5015883..5016191 Streptomyces avermitilis MA-4680 1215017 NP_825276.1 CDS SAV_4099 NC_003155.4 5016402 5017253 D integral membrane protein 5016402..5017253 Streptomyces avermitilis MA-4680 1215018 NP_825277.1 CDS SAV_4100 NC_003155.4 5017243 5018577 D integral membrane protein 5017243..5018577 Streptomyces avermitilis MA-4680 1215019 NP_825278.1 CDS SAV_4101 NC_003155.4 5018592 5020133 D hypothetical protein 5018592..5020133 Streptomyces avermitilis MA-4680 1215020 NP_825279.1 CDS SAV_4102 NC_003155.4 5020173 5021603 D ATP/GTP-binding protein 5020173..5021603 Streptomyces avermitilis MA-4680 1215021 NP_825280.1 CDS SAV_4103 NC_003155.4 5021723 5023351 D hypothetical protein 5021723..5023351 Streptomyces avermitilis MA-4680 1215022 NP_825281.1 CDS SAV_4104 NC_003155.4 5023429 5023974 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(5023429..5023974) Streptomyces avermitilis MA-4680 1215023 NP_825282.1 CDS SAV_4105 NC_003155.4 5029929 5030477 R MarR family transcriptional regulator complement(5029929..5030477) Streptomyces avermitilis MA-4680 1215024 NP_825283.1 CDS SAV_4106 NC_003155.4 5030639 5031910 D PF07690: Major Facilitator Superfamily; hypothetical protein 5030639..5031910 Streptomyces avermitilis MA-4680 1215025 NP_825284.1 CDS SAV_4107 NC_003155.4 5031992 5032807 R methyltransferase complement(5031992..5032807) Streptomyces avermitilis MA-4680 1215026 NP_825285.1 CDS prpI3 NC_003155.4 5032918 5034567 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase complement(5032918..5034567) Streptomyces avermitilis MA-4680 1215027 NP_825286.1 CDS ndh3 NC_003155.4 5034691 5036010 R PF00070: Pyridine nucleotide-disulphide oxidoreductase; NADH dehydrogenase complement(5034691..5036010) Streptomyces avermitilis MA-4680 1215028 NP_825287.1 CDS SAV_4110 NC_003155.4 5036435 5037193 D TetR family transcriptional regulator 5036435..5037193 Streptomyces avermitilis MA-4680 1215029 NP_825288.1 CDS SAV_4111 NC_003155.4 5037479 5040880 R transcriptional regulator complement(5037479..5040880) Streptomyces avermitilis MA-4680 1215030 NP_825289.1 CDS SAV_4112 NC_003155.4 5041026 5042774 R PF00733: Asparagine synthase; hypothetical protein complement(5041026..5042774) Streptomyces avermitilis MA-4680 1215031 NP_825290.1 CDS sap NC_003155.4 5043789 5045213 D PF06036: Streptomyces protein of unknown function (DUF921); sporulation associated protein 5043789..5045213 Streptomyces avermitilis MA-4680 1210877 NP_825291.1 CDS SAV_4114 NC_003155.4 5045350 5046591 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 5045350..5046591 Streptomyces avermitilis MA-4680 1215032 NP_825292.1 CDS trmB NC_003155.4 5046990 5047862 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 5046990..5047862 Streptomyces avermitilis MA-4680 1215033 NP_825293.1 CDS SAV_4116 NC_003155.4 5047927 5049288 D hypothetical protein 5047927..5049288 Streptomyces avermitilis MA-4680 1215034 NP_825294.1 CDS SAV_4117 NC_003155.4 5049328 5050272 R PF00248: Aldo/keto reductase family; oxidoreductase complement(5049328..5050272) Streptomyces avermitilis MA-4680 1215035 NP_825295.1 CDS SAV_4118 NC_003155.4 5050422 5051465 R PF01551: Peptidase family M23; peptidase complement(5050422..5051465) Streptomyces avermitilis MA-4680 1215036 NP_825296.1 CDS ribG NC_003155.4 5052156 5053286 R riboflavin/cytosine deaminase complement(5052156..5053286) Streptomyces avermitilis MA-4680 1210879 NP_825297.1 CDS SAV_4120 NC_003155.4 5053338 5053838 D MarR family transcriptional regulator 5053338..5053838 Streptomyces avermitilis MA-4680 1215037 NP_825298.1 CDS ribA NC_003155.4 5054141 5054848 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 5054141..5054848 Streptomyces avermitilis MA-4680 1210880 NP_825299.1 CDS SAV_4122 NC_003155.4 5055705 5057240 R PF00324: Amino acid permease; amino acid permease complement(5055705..5057240) Streptomyces avermitilis MA-4680 1215038 NP_825300.1 CDS SAV_4123 NC_003155.4 5057467 5059710 R PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase complement(5057467..5059710) Streptomyces avermitilis MA-4680 1215039 NP_825301.1 CDS SAV_4124 NC_003155.4 5060143 5060583 R hypothetical protein complement(5060143..5060583) Streptomyces avermitilis MA-4680 1215040 NP_825302.1 CDS SAV_4125 NC_003155.4 5060838 5061188 R PF06262: Domain of unknown function (DUF1025); hypothetical protein complement(5060838..5061188) Streptomyces avermitilis MA-4680 1215041 NP_825303.1 CDS SAV_4126 NC_003155.4 5061300 5062937 D PF00149: Calcineurin-like phosphoesterase; hypothetical protein 5061300..5062937 Streptomyces avermitilis MA-4680 1215042 NP_825304.1 CDS SAV_4127 NC_003155.4 5063566 5063889 D hypothetical protein 5063566..5063889 Streptomyces avermitilis MA-4680 1215043 NP_825305.1 CDS hrpA NC_003155.4 5064051 5068028 D ATP-dependent helicase 5064051..5068028 Streptomyces avermitilis MA-4680 1210885 NP_825306.1 CDS SAV_4129 NC_003155.4 5068384 5068575 D hypothetical protein 5068384..5068575 Streptomyces avermitilis MA-4680 1215044 NP_825307.1 CDS SAV_4130 NC_003155.4 5069093 5069299 R MerR family transcriptional regulator complement(5069093..5069299) Streptomyces avermitilis MA-4680 1215045 NP_825308.1 CDS SAV_4131 NC_003155.4 5069900 5070745 R hypothetical protein complement(5069900..5070745) Streptomyces avermitilis MA-4680 1215046 NP_825309.1 CDS vdh NC_003155.4 5070973 5072058 D valine dehydrogenase (NADP+) 5070973..5072058 Streptomyces avermitilis MA-4680 1210887 NP_825310.1 CDS SAV_4133 NC_003155.4 5072358 5072609 D hypothetical protein 5072358..5072609 Streptomyces avermitilis MA-4680 1215047 NP_825311.1 CDS purM NC_003155.4 5072757 5073851 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(5072757..5073851) Streptomyces avermitilis MA-4680 1210888 NP_825312.1 CDS purF NC_003155.4 5073884 5075464 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(5073884..5075464) Streptomyces avermitilis MA-4680 1210889 NP_825313.1 CDS SAV_4136 NC_003155.4 5075496 5076371 R PF03724: Domain of unknown function (306); hypothetical protein complement(5075496..5076371) Streptomyces avermitilis MA-4680 1215048 NP_825314.1 CDS SAV_4137 NC_003155.4 5076528 5077325 R hypothetical protein complement(5076528..5077325) Streptomyces avermitilis MA-4680 1215049 NP_825315.1 CDS purL NC_003155.4 5077540 5079798 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(5077540..5079798) Streptomyces avermitilis MA-4680 1210890 NP_825316.1 CDS purQ NC_003155.4 5079795 5080499 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I complement(5079795..5080499) Streptomyces avermitilis MA-4680 1210891 NP_825317.1 CDS purS NC_003155.4 5080496 5080762 R With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS complement(5080496..5080762) Streptomyces avermitilis MA-4680 1215050 NP_825318.1 CDS SAV_4141 NC_003155.4 5081122 5081439 D Lsr2-like protein 5081122..5081439 Streptomyces avermitilis MA-4680 1215051 NP_825319.1 CDS SAV_4142 NC_003155.4 5082037 5083050 D ABC transporter ATP-binding protein 5082037..5083050 Streptomyces avermitilis MA-4680 1215052 NP_825320.1 CDS SAV_4143 NC_003155.4 5083047 5083826 D ABC transporter permease 5083047..5083826 Streptomyces avermitilis MA-4680 1215053 NP_825321.1 CDS SAV_4144 NC_003155.4 5083855 5085111 D two-component system sensor kinase 5083855..5085111 Streptomyces avermitilis MA-4680 1215054 NP_825322.1 CDS SAV_4145 NC_003155.4 5085153 5085755 D two-component system response regulator 5085153..5085755 Streptomyces avermitilis MA-4680 1215055 NP_825323.1 CDS hemH NC_003155.4 5085906 5086805 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(5085906..5086805) Streptomyces avermitilis MA-4680 1210894 NP_825324.1 CDS SAV_4147 NC_003155.4 5087009 5088553 R hypothetical protein complement(5087009..5088553) Streptomyces avermitilis MA-4680 1215056 NP_825325.1 CDS SAV_4148 NC_003155.4 5088716 5090698 R similar to phage coat protein; hypothetical protein complement(5088716..5090698) Streptomyces avermitilis MA-4680 1215057 NP_825326.1 CDS purD NC_003155.4 5091096 5092349 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(5091096..5092349) Streptomyces avermitilis MA-4680 1210895 NP_825327.1 CDS dnaZX NC_003155.4 5092430 5094970 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(5092430..5094970) Streptomyces avermitilis MA-4680 1210896 NP_825328.1 CDS prpC6 NC_003155.4 5095612 5098305 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 5095612..5098305 Streptomyces avermitilis MA-4680 1215058 NP_825329.1 CDS SAV_4152 NC_003155.4 5098501 5100099 D PF01433: Peptidase family M1; metallopeptidase 5098501..5100099 Streptomyces avermitilis MA-4680 1215059 NP_825330.1 CDS SAV_4153 NC_003155.4 5100404 5102419 D amidase 5100404..5102419 Streptomyces avermitilis MA-4680 1215060 NP_825331.1 CDS cspD3 NC_003155.4 5102772 5102975 D cold shock protein 5102772..5102975 Streptomyces avermitilis MA-4680 1210898 NP_825332.1 CDS SAV_4155 NC_003155.4 5103407 5104915 D PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase 5103407..5104915 Streptomyces avermitilis MA-4680 1215061 NP_825333.1 CDS SAV_4156 NC_003155.4 5105027 5105323 D PF00571: CBS domain; hypothetical protein 5105027..5105323 Streptomyces avermitilis MA-4680 1215062 NP_825334.1 CDS SAV_4157 NC_003155.4 5105369 5105683 D hypothetical protein 5105369..5105683 Streptomyces avermitilis MA-4680 1215063 NP_825335.1 CDS SAV_4158 NC_003155.4 5105820 5107415 R two-component system sensor kinase complement(5105820..5107415) Streptomyces avermitilis MA-4680 1215064 NP_825336.1 CDS SAV_4159 NC_003155.4 5107519 5108241 R two-component system response regulator complement(5107519..5108241) Streptomyces avermitilis MA-4680 1215065 NP_825337.1 CDS SAV_4160 NC_003155.4 5108379 5109572 D hypothetical protein 5108379..5109572 Streptomyces avermitilis MA-4680 1215066 NP_825338.1 CDS SAV_4161 NC_003155.4 5109633 5110922 D hypothetical protein 5109633..5110922 Streptomyces avermitilis MA-4680 1215067 NP_825339.1 CDS SAV_4162 NC_003155.4 5111059 5112135 R hypothetical protein complement(5111059..5112135) Streptomyces avermitilis MA-4680 1215068 NP_825340.1 CDS SAV_4163 NC_003155.4 5112227 5113102 R hypothetical protein complement(5112227..5113102) Streptomyces avermitilis MA-4680 1215069 NP_825341.1 CDS SAV_4164 NC_003155.4 5113132 5114418 R glycine-rich protein; hypothetical protein complement(5113132..5114418) Streptomyces avermitilis MA-4680 1215070 NP_825342.1 CDS SAV_4165 NC_003155.4 5114915 5115271 D PF05239: PRC-barrel domain; hypothetical protein 5114915..5115271 Streptomyces avermitilis MA-4680 1215071 NP_825343.1 CDS SAV_4166 NC_003155.4 5115396 5117165 R PF04234: Copper resistance protein CopC; hypothetical protein complement(5115396..5117165) Streptomyces avermitilis MA-4680 1215072 NP_825344.1 CDS SAV_4168 NC_003155.4 5117411 5118334 R frameshift; dehydrogenase complement(5117411..5118334) Streptomyces avermitilis MA-4680 1215073 NP_825345.1 CDS SAV_4167 NC_003155.4 5117503 5117910 R frameshift, PF00106: short chain dehydrogenase; dehydrogenase complement(5117503..5117910) Streptomyces avermitilis MA-4680 1215074 NP_825346.1 CDS SAV_4169 NC_003155.4 5118322 5118801 R PF06172: Protein of unknown function (DUF985); hypothetical protein complement(5118322..5118801) Streptomyces avermitilis MA-4680 1215075 NP_825347.1 CDS SAV_4170 NC_003155.4 5118812 5119426 R alcB homolog; aceytltranferase complement(5118812..5119426) Streptomyces avermitilis MA-4680 1215076 NP_825348.1 CDS pacB2 NC_003155.4 5119416 5121623 R PF01804: Penicillin amidase; penicillin acylase complement(5119416..5121623) Streptomyces avermitilis MA-4680 1215077 NP_825349.1 CDS SAV_4172 NC_003155.4 5121847 5122473 D PF03729: Short repeat of unknown function (DUF308); hypothetical protein 5121847..5122473 Streptomyces avermitilis MA-4680 1215078 NP_825350.1 CDS SAV_4173 NC_003155.4 5122539 5123207 D PF03729: Short repeat of unknown function (DUF308); hypothetical protein 5122539..5123207 Streptomyces avermitilis MA-4680 1215079 NP_825351.1 CDS SAV_4174 NC_003155.4 5123221 5123640 D hypothetical protein 5123221..5123640 Streptomyces avermitilis MA-4680 1215080 NP_825352.1 CDS SAV_4175 NC_003155.4 5123892 5125466 R PF05872: Bacterial protein of unknown function (DUF853); hypothetical protein complement(5123892..5125466) Streptomyces avermitilis MA-4680 1215081 NP_825353.1 CDS SAV_4176 NC_003155.4 5125590 5125886 D hypothetical protein 5125590..5125886 Streptomyces avermitilis MA-4680 1215082 NP_825354.1 CDS SAV_4177 NC_003155.4 5126033 5126662 D hypothetical protein 5126033..5126662 Streptomyces avermitilis MA-4680 1215083 NP_825355.1 CDS upp NC_003155.4 5126876 5127511 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(5126876..5127511) Streptomyces avermitilis MA-4680 1210899 NP_825356.1 CDS SAV_4179 NC_003155.4 5128249 5128800 D hypothetical protein 5128249..5128800 Streptomyces avermitilis MA-4680 1215084 NP_825357.1 CDS cdd3 NC_003155.4 5129204 5129632 D PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region; cytidine/deoxycytidine deaminase 5129204..5129632 Streptomyces avermitilis MA-4680 1215085 NP_825358.1 CDS int10 NC_003155.4 5130705 5131628 R phage integrase near tRNA gene, PF00589: Phage integrase family; integrase/recombinase complement(5130705..5131628) Streptomyces avermitilis MA-4680 1215086 NP_825359.1 CDS SAV_4182 NC_003155.4 5131802 5132035 D hypothetical protein 5131802..5132035 Streptomyces avermitilis MA-4680 1215087 NP_825360.1 CDS SAV_4183 NC_003155.4 5133481 5133660 D hypothetical protein 5133481..5133660 Streptomyces avermitilis MA-4680 1215088 NP_825361.1 CDS SAV_4184 NC_003155.4 5133707 5134000 D hypothetical protein 5133707..5134000 Streptomyces avermitilis MA-4680 1215089 NP_825362.1 CDS sig34 NC_003155.4 5134202 5135131 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 5134202..5135131 Streptomyces avermitilis MA-4680 1210901 NP_825363.1 CDS sig35 NC_003155.4 5135376 5136299 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 5135376..5136299 Streptomyces avermitilis MA-4680 1210902 NP_825364.1 CDS SAV_4187 NC_003155.4 5136384 5137199 D hypothetical protein 5136384..5137199 Streptomyces avermitilis MA-4680 1215090 NP_825365.1 CDS SAV_4188 NC_003155.4 5137228 5137506 R hypothetical protein complement(5137228..5137506) Streptomyces avermitilis MA-4680 1215091 NP_825366.1 CDS SAV_4189 NC_003155.4 5137672 5138187 D MarR family transcriptional regulator 5137672..5138187 Streptomyces avermitilis MA-4680 1215092 NP_825367.1 CDS SAV_4190 NC_003155.4 5138210 5140771 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 5138210..5140771 Streptomyces avermitilis MA-4680 1215093 NP_825368.1 CDS SAV_4191 NC_003155.4 5140882 5141703 D PF04264: YceI like family; hypothetical protein 5140882..5141703 Streptomyces avermitilis MA-4680 1215094 NP_825369.1 CDS SAV_4192 NC_003155.4 5141773 5142243 D ATP/GTP-binding protein 5141773..5142243 Streptomyces avermitilis MA-4680 1215095 NP_825370.1 CDS SAV_4193 NC_003155.4 5142316 5143086 R TetR family transcriptional regulator complement(5142316..5143086) Streptomyces avermitilis MA-4680 1215096 NP_825371.1 CDS SAV_4194 NC_003155.4 5143193 5144689 R homolog of virginiamycin S resistance gene (varS), PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(5143193..5144689) Streptomyces avermitilis MA-4680 1215097 NP_825372.1 CDS SAV_4195 NC_003155.4 5144801 5147050 R PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; hypothetical protein complement(5144801..5147050) Streptomyces avermitilis MA-4680 1215098 NP_825373.1 CDS SAV_4196 NC_003155.4 5147047 5148588 R homolog of dolichyl-phosphate beta-glucosyltransferase, PF04138: GtrA-like protein; glycosyl transferase complement(5147047..5148588) Streptomyces avermitilis MA-4680 1215099 NP_825374.1 CDS SAV_4197 NC_003155.4 5148603 5150222 R two-component system sensor kinase complement(5148603..5150222) Streptomyces avermitilis MA-4680 1215100 NP_825375.1 CDS SAV_4198 NC_003155.4 5150219 5151028 R two-component system response regulator complement(5150219..5151028) Streptomyces avermitilis MA-4680 1215101 NP_825376.1 CDS SAV_4199 NC_003155.4 5151183 5152112 R PF04909: Amidohydrolase; hypothetical protein complement(5151183..5152112) Streptomyces avermitilis MA-4680 1215102 NP_825377.1 CDS SAV_4200 NC_003155.4 5152096 5152542 R PF03992: Antibiotic biosynthesis monooxygenase; hypothetical protein complement(5152096..5152542) Streptomyces avermitilis MA-4680 1215103 NP_825378.1 CDS SAV_4201 NC_003155.4 5152683 5153546 R hypothetical protein complement(5152683..5153546) Streptomyces avermitilis MA-4680 1215104 NP_825379.1 CDS SAV_4202 NC_003155.4 5153627 5154115 R hypothetical protein complement(5153627..5154115) Streptomyces avermitilis MA-4680 1215105 NP_825380.1 CDS SAV_4203 NC_003155.4 5154416 5154820 D similar to cell wall lysis enzyme of phage; near tRNA genes; peptidoglycan-binding protein 5154416..5154820 Streptomyces avermitilis MA-4680 1215106 NP_825381.1 CDS SAV_4204 NC_003155.4 5155522 5155989 D PF00720: Subtilisin inhibitor-like; protein 5155522..5155989 Streptomyces avermitilis MA-4680 1215107 NP_825382.1 CDS SAV_4205 NC_003155.4 5156280 5160719 D two-component system sensor kinase/response regulator, bifunctional protein 5156280..5160719 Streptomyces avermitilis MA-4680 1215108 NP_825383.1 CDS fadD9 NC_003155.4 5160810 5162486 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(5160810..5162486) Streptomyces avermitilis MA-4680 1210905 NP_825384.1 CDS sig36 NC_003155.4 5162654 5163124 R ECF subfamily RNA polymerase sigma factor complement(5162654..5163124) Streptomyces avermitilis MA-4680 1210906 NP_825385.1 CDS ltp3 NC_003155.4 5163382 5164548 R lipid-transfer protein complement(5163382..5164548) Streptomyces avermitilis MA-4680 1210907 NP_825386.1 CDS SAV_4209 NC_003155.4 5164545 5164940 R probably involved in the lipid metabolism, PF01575: MaoC like domain; hypothetical protein complement(5164545..5164940) Streptomyces avermitilis MA-4680 1215109 NP_825387.1 CDS fadE28 NC_003155.4 5164937 5166073 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(5164937..5166073) Streptomyces avermitilis MA-4680 1210908 NP_825388.1 CDS SAV_4211 NC_003155.4 5166075 5167025 R PF01796: Domain of unknown function DUF35; hypothetical protein complement(5166075..5167025) Streptomyces avermitilis MA-4680 1215110 NP_825389.1 CDS fadE22 NC_003155.4 5167022 5168311 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(5167022..5168311) Streptomyces avermitilis MA-4680 1210909 NP_825390.1 CDS SAV_4213 NC_003155.4 5168572 5168808 R hypothetical protein complement(5168572..5168808) Streptomyces avermitilis MA-4680 1215111 NP_825391.1 CDS SAV_4214 NC_003155.4 5169189 5170106 D hypothetical protein 5169189..5170106 Streptomyces avermitilis MA-4680 1215112 NP_825392.1 CDS SAV_4215 NC_003155.4 5172533 5172976 R IS1647-like transposase complement(5172533..5172976) Streptomyces avermitilis MA-4680 1215113 NP_825393.2 CDS SAV_4216 NC_003155.4 5172868 5173350 R IS1647-like transposase complement(5172868..5173350) Streptomyces avermitilis MA-4680 1215114 NP_825394.1 CDS SAV_4217 NC_003155.4 5173661 5174278 D hypothetical protein 5173661..5174278 Streptomyces avermitilis MA-4680 1215115 NP_825395.1 CDS SAV_4218 NC_003155.4 5174345 5174863 R hypothetical protein complement(5174345..5174863) Streptomyces avermitilis MA-4680 1215116 NP_825396.1 CDS SAV_4219 NC_003155.4 5174965 5176368 D PF01580: FtsK/SpoIIIE family; hypothetical protein 5174965..5176368 Streptomyces avermitilis MA-4680 1215117 NP_825397.1 CDS SAV_4220 NC_003155.4 5176576 5176899 D hypothetical protein 5176576..5176899 Streptomyces avermitilis MA-4680 1215118 NP_825398.1 CDS SAV_4221 NC_003155.4 5176989 5177345 D hypothetical protein 5176989..5177345 Streptomyces avermitilis MA-4680 1215119 NP_825399.1 CDS SAV_4222 NC_003155.4 5177342 5177554 D hypothetical protein 5177342..5177554 Streptomyces avermitilis MA-4680 1215120 NP_825400.1 CDS SAV_4223 NC_003155.4 5177841 5179259 R PF00089: Trypsin; serine protease complement(5177841..5179259) Streptomyces avermitilis MA-4680 1215121 NP_825401.1 CDS glpQ2 NC_003155.4 5179544 5180353 D glycerophosphoryl diester phosphodiesterase 5179544..5180353 Streptomyces avermitilis MA-4680 1210911 NP_825402.1 CDS SAV_4225 NC_003155.4 5180472 5181125 D regulatory protein 5180472..5181125 Streptomyces avermitilis MA-4680 1215122 NP_825403.1 CDS SAV_4226 NC_003155.4 5181331 5182296 D PF02810: SEC-C motif; hypothetical protein 5181331..5182296 Streptomyces avermitilis MA-4680 1215123 NP_825404.1 CDS SAV_4227 NC_003155.4 5182632 5183207 R hypothetical protein complement(5182632..5183207) Streptomyces avermitilis MA-4680 1215124 NP_825405.1 CDS SAV_4228 NC_003155.4 5183263 5183928 R hypothetical protein complement(5183263..5183928) Streptomyces avermitilis MA-4680 1215125 NP_825406.1 CDS prpB7 NC_003155.4 5184516 5185910 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 5184516..5185910 Streptomyces avermitilis MA-4680 1215126 NP_825407.1 CDS pepP NC_003155.4 5185995 5187458 D PF00557: metallopeptidase family M24; aminopeptidase P 5185995..5187458 Streptomyces avermitilis MA-4680 1210912 NP_825408.1 CDS SAV_4231 NC_003155.4 5187590 5189005 D GntR family transcriptional regulator 5187590..5189005 Streptomyces avermitilis MA-4680 1215127 NP_825409.1 CDS SAV_4232 NC_003155.4 5189096 5190565 D PF07690: Major Facilitator Superfamily; hypothetical protein 5189096..5190565 Streptomyces avermitilis MA-4680 1215128 NP_825410.1 CDS mdcB NC_003155.4 5190540 5191379 R 2-(5''-triphosphoribosyl)-3'-dephospho- CoA synthase complement(5190540..5191379) Streptomyces avermitilis MA-4680 1210913 NP_825411.1 CDS SAV_4234 NC_003155.4 5191389 5192423 R PF00775: Dioxygenase; protocatechuate dioxygenase complement(5191389..5192423) Streptomyces avermitilis MA-4680 1215129 NP_825412.1 CDS SAV_4235 NC_003155.4 5192478 5195684 R PF01885: RNA 2'-phosphotransferase, Tpt1 / KptA family; hypothetical protein complement(5192478..5195684) Streptomyces avermitilis MA-4680 1215130 NP_825413.1 CDS SAV_4236 NC_003155.4 5195791 5196249 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein complement(5195791..5196249) Streptomyces avermitilis MA-4680 1215131 NP_825414.1 CDS SAV_4237 NC_003155.4 5196492 5197385 D hypothetical protein 5196492..5197385 Streptomyces avermitilis MA-4680 1215132 NP_825415.1 CDS SAV_4238 NC_003155.4 5197592 5198326 D hypothetical protein 5197592..5198326 Streptomyces avermitilis MA-4680 1215133 NP_825416.1 CDS SAV_4239 NC_003155.4 5198431 5199084 D PF02630: SCO1/SenC; hypothetical protein 5198431..5199084 Streptomyces avermitilis MA-4680 1215134 NP_825417.1 CDS SAV_4240 NC_003155.4 5199081 5199548 D PF04314: Protein of unknown function (DUF461); hypothetical protein 5199081..5199548 Streptomyces avermitilis MA-4680 1215135 NP_825418.1 CDS SAV_4241 NC_003155.4 5199736 5201820 D PF04234: Copper resistance protein CopC; integral membrane protein 5199736..5201820 Streptomyces avermitilis MA-4680 1215136 NP_825419.1 CDS SAV_4242 NC_003155.4 5201829 5203190 D PF04261: Dyp-type peroxidase family; hypothetical protein 5201829..5203190 Streptomyces avermitilis MA-4680 1215137 NP_825420.1 CDS pheA NC_003155.4 5203261 5204193 D prephenate dehydratase 5203261..5204193 Streptomyces avermitilis MA-4680 1210914 NP_825421.1 CDS serS1 NC_003155.4 5204797 5206074 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 5204797..5206074 Streptomyces avermitilis MA-4680 1210915 NP_825422.1 CDS SAV_4245 NC_003155.4 5206071 5206901 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 5206071..5206901 Streptomyces avermitilis MA-4680 1215138 NP_825423.1 CDS SAV_4246 NC_003155.4 5207285 5207524 R hypothetical protein complement(5207285..5207524) Streptomyces avermitilis MA-4680 1215139 NP_825424.1 CDS SAV_4247 NC_003155.4 5207671 5208390 R integral membrane protein complement(5207671..5208390) Streptomyces avermitilis MA-4680 1215140 NP_825425.1 CDS SAV_4248 NC_003155.4 5208401 5209312 R ABC transporter ATP-binding protein complement(5208401..5209312) Streptomyces avermitilis MA-4680 1215141 NP_825426.1 CDS SAV_4249 NC_003155.4 5209309 5210238 R integral membrane protein complement(5209309..5210238) Streptomyces avermitilis MA-4680 1215142 NP_825427.1 CDS SAV_4250 NC_003155.4 5210228 5211190 R ABC transporter ATP-binding protein complement(5210228..5211190) Streptomyces avermitilis MA-4680 1215143 NP_825428.1 CDS SAV_4251 NC_003155.4 5211430 5212308 D hypothetical protein 5211430..5212308 Streptomyces avermitilis MA-4680 1215144 NP_825429.1 CDS SAV_4252 NC_003155.4 5212305 5214059 D PF00106: short chain dehydrogenase; short chain dehydrogenase 5212305..5214059 Streptomyces avermitilis MA-4680 1215145 NP_825430.1 CDS SAV_4253 NC_003155.4 5214056 5214985 D hypothetical protein 5214056..5214985 Streptomyces avermitilis MA-4680 1215146 NP_825431.1 CDS SAV_4254 NC_003155.4 5215099 5216022 D MerR family transcriptional regulator 5215099..5216022 Streptomyces avermitilis MA-4680 1215147 NP_825432.1 CDS SAV_4255 NC_003155.4 5216144 5217214 D PF00296: Luciferase-like monooxygenase; hypothetical protein 5216144..5217214 Streptomyces avermitilis MA-4680 1215148 NP_825433.1 CDS SAV_4256 NC_003155.4 5217388 5218305 D PF00702: haloacid dehalogenase-like hydrolase; hypothetical protein 5217388..5218305 Streptomyces avermitilis MA-4680 1215149 NP_825434.1 CDS SAV_4257 NC_003155.4 5218386 5220092 R two-component system sensor kinase complement(5218386..5220092) Streptomyces avermitilis MA-4680 1215150 NP_825435.1 CDS cydCD NC_003155.4 5220167 5223721 R ABC transporter ATP-binding protein complement(5220167..5223721) Streptomyces avermitilis MA-4680 1210917 NP_825436.1 CDS cydB1 NC_003155.4 5223782 5224786 R cytochrome bd-I oxidase subunit II complement(5223782..5224786) Streptomyces avermitilis MA-4680 1210918 NP_825437.1 CDS cydA1 NC_003155.4 5224806 5226314 R cytochrome bd-I oxidase subunit I complement(5224806..5226314) Streptomyces avermitilis MA-4680 1210919 NP_825438.1 CDS hisC2 NC_003155.4 5226731 5227810 R EC:2.6.1.9; putative aminotransferase complement(5226731..5227810) Streptomyces avermitilis MA-4680 1210920 NP_825439.1 CDS rstP NC_003155.4 5228198 5229310 D LacI family transcriptional regulator 5228198..5229310 Streptomyces avermitilis MA-4680 1210921 NP_825440.1 CDS prpA2 NC_003155.4 5229540 5230649 D PF00149: Calcineurin-like phosphoesterase; serine/threonine protein phosphatase 5229540..5230649 Streptomyces avermitilis MA-4680 1210922 NP_825441.1 CDS SAV_4264 NC_003155.4 5230838 5231695 D hypothetical protein 5230838..5231695 Streptomyces avermitilis MA-4680 1215151 NP_825442.1 CDS thiA NC_003155.4 5231881 5233686 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(5231881..5233686) Streptomyces avermitilis MA-4680 1210923 NP_825443.1 CDS SAV_4266 NC_003155.4 5233907 5235349 D hypothetical protein 5233907..5235349 Streptomyces avermitilis MA-4680 1215152 NP_825444.1 CDS ssgA1 NC_003155.4 5235517 5235924 R PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein complement(5235517..5235924) Streptomyces avermitilis MA-4680 1210924 NP_825445.1 CDS ssfR NC_003155.4 5236053 5236778 R IclR family transcriptional regulator complement(5236053..5236778) Streptomyces avermitilis MA-4680 1210925 NP_825446.1 CDS SAV_4269 NC_003155.4 5237173 5237385 R membrane spanning protein complement(5237173..5237385) Streptomyces avermitilis MA-4680 1215153 NP_825447.1 CDS SAV_4270 NC_003155.4 5237549 5237866 R PF00190: Cupin; hypothetical protein complement(5237549..5237866) Streptomyces avermitilis MA-4680 1215154 NP_825448.1 CDS SAV_4271 NC_003155.4 5237980 5238360 D PF04020: Membrane protein of unknown function; hypothetical protein 5237980..5238360 Streptomyces avermitilis MA-4680 1215155 NP_825449.1 CDS ptpB2 NC_003155.4 5238369 5238860 D PF01451: Low molecular weight phosphotyrosine protein phosphatase; low molecular weight protein tyrosine phosphatase 5238369..5238860 Streptomyces avermitilis MA-4680 1210926 NP_825450.1 CDS cysA1 NC_003155.4 5238857 5240002 D catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; cystathionine gamma-lyase 5238857..5240002 Streptomyces avermitilis MA-4680 1210927 NP_825451.1 CDS abaB1 NC_003155.4 5240218 5241123 D LysR family transcriptional regulator 5240218..5241123 Streptomyces avermitilis MA-4680 1210928 NP_825452.1 CDS SAV_4275 NC_003155.4 5241186 5241668 D PF00293: NUDIX domain; hypothetical protein 5241186..5241668 Streptomyces avermitilis MA-4680 1215156 NP_825453.1 CDS fhbA NC_003155.4 5241692 5243389 R flavohemoprotein complement(5241692..5243389) Streptomyces avermitilis MA-4680 1215157 NP_825454.1 CDS SAV_4277 NC_003155.4 5243788 5244447 R PF00702: haloacid dehalogenase-like hydrolase; hypothetical protein complement(5243788..5244447) Streptomyces avermitilis MA-4680 1215158 NP_825455.1 CDS SAV_4278 NC_003155.4 5244596 5245462 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 5244596..5245462 Streptomyces avermitilis MA-4680 1215159 NP_825456.1 CDS SAV_4279 NC_003155.4 5245573 5245992 R PF03928: Domain of unknown function (DUF336); hypothetical protein complement(5245573..5245992) Streptomyces avermitilis MA-4680 1215160 NP_825457.1 CDS SAV_4280 NC_003155.4 5246135 5247343 R similar to cmlR, PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(5246135..5247343) Streptomyces avermitilis MA-4680 1215161 NP_825458.1 CDS SAV_4281 NC_003155.4 5247484 5247942 D MarR family transcriptional regulator 5247484..5247942 Streptomyces avermitilis MA-4680 1215162 NP_825459.1 CDS SAV_4282 NC_003155.4 5247952 5248404 D transcriptional regulator 5247952..5248404 Streptomyces avermitilis MA-4680 1215163 NP_825460.1 CDS blaA2 NC_003155.4 5248526 5249911 R PF00144: Beta-lactamase; beta-lactamase complement(5248526..5249911) Streptomyces avermitilis MA-4680 1210929 NP_825461.1 CDS dnaB NC_003155.4 5249988 5251463 R replicative DNA helicase complement(5249988..5251463) Streptomyces avermitilis MA-4680 1210930 NP_825462.1 CDS dinF NC_003155.4 5251914 5253260 D DNA-damage-inducible protein F 5251914..5253260 Streptomyces avermitilis MA-4680 1210931 NP_825463.1 CDS rplI NC_003155.4 5253458 5253904 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(5253458..5253904) Streptomyces avermitilis MA-4680 1210932 NP_825464.1 CDS rpsR NC_003155.4 5253923 5254159 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(5253923..5254159) Streptomyces avermitilis MA-4680 1210933 NP_825465.1 CDS ssb NC_003155.4 5254217 5254825 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(5254217..5254825) Streptomyces avermitilis MA-4680 1210934 NP_825466.1 CDS rpsF NC_003155.4 5254905 5255195 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(5254905..5255195) Streptomyces avermitilis MA-4680 1210935 NP_825467.1 CDS SAV_4290 NC_003155.4 5255517 5255831 D hypothetical protein 5255517..5255831 Streptomyces avermitilis MA-4680 1215164 NP_825468.1 CDS SAV_4291 NC_003155.4 5256054 5257175 D PF02388: FemAB family; hypothetical protein 5256054..5257175 Streptomyces avermitilis MA-4680 1215165 NP_825469.1 CDS SAV_4292 NC_003155.4 5257274 5258305 D PF01168: alanine racemase, N-terminal domain; hypothetical protein 5257274..5258305 Streptomyces avermitilis MA-4680 1215166 NP_825470.1 CDS SAV_4293 NC_003155.4 5258389 5259906 R PF05007: Mannosyltransferase (PIG-M); hypothetical protein complement(5258389..5259906) Streptomyces avermitilis MA-4680 1215167 NP_825471.1 CDS pbp5 NC_003155.4 5260016 5262805 R PF00912: Transglycosylase; penicillin-binding protein complement(5260016..5262805) Streptomyces avermitilis MA-4680 1210936 NP_825472.1 CDS SAV_4295 NC_003155.4 5263084 5263767 D ParR family transcriptional regulator 5263084..5263767 Streptomyces avermitilis MA-4680 1215168 NP_825473.1 CDS ino1 NC_003155.4 5263812 5264894 D PF01658: Myo-inositol-1-phosphate synthase; 1L-myo-inositol-1-phosphate synthase 5263812..5264894 Streptomyces avermitilis MA-4680 1215169 NP_825474.1 CDS SAV_4297 NC_003155.4 5264972 5266234 D PF07690: Major Facilitator Superfamily; hypothetical protein 5264972..5266234 Streptomyces avermitilis MA-4680 1215170 NP_825475.1 CDS SAV_4298 NC_003155.4 5266349 5266840 D hypothetical protein 5266349..5266840 Streptomyces avermitilis MA-4680 1215171 NP_825476.1 CDS pcnA NC_003155.4 5266959 5268401 R RNA nucleotidyltransferase complement(5266959..5268401) Streptomyces avermitilis MA-4680 1210937 NP_825477.1 CDS SAV_4300 NC_003155.4 5268648 5271065 D hypothetical protein 5268648..5271065 Streptomyces avermitilis MA-4680 1215172 NP_825478.1 CDS SAV_4301 NC_003155.4 5271112 5273379 D PF03023: MviN-like protein; hypothetical protein 5271112..5273379 Streptomyces avermitilis MA-4680 1215173 NP_825479.1 CDS SAV_4302 NC_003155.4 5273498 5275219 D PF00069: Protein kinase domain; hypothetical protein 5273498..5275219 Streptomyces avermitilis MA-4680 1215174 NP_825480.1 CDS sig37 NC_003155.4 5275249 5275962 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase; RNA polymerase sigma factor SigM 5275249..5275962 Streptomyces avermitilis MA-4680 1210938 NP_825481.1 CDS SAV_4304 NC_003155.4 5275959 5276882 D hypothetical protein 5275959..5276882 Streptomyces avermitilis MA-4680 1215175 NP_825482.1 CDS trxB1 NC_003155.4 5277067 5278038 D thioredoxin reductase (NADPH) 5277067..5278038 Streptomyces avermitilis MA-4680 1210939 NP_825483.1 CDS trxA1 NC_003155.4 5278082 5278414 D thioredoxin 5278082..5278414 Streptomyces avermitilis MA-4680 1210940 NP_825484.1 CDS SAV_4307 NC_003155.4 5278554 5279171 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(5278554..5279171) Streptomyces avermitilis MA-4680 1215176 NP_825485.1 CDS parB NC_003155.4 5279501 5280604 R PF02195: ParB-like nuclease domain; ParB-like protein complement(5279501..5280604) Streptomyces avermitilis MA-4680 1210941 NP_825486.1 CDS parA1 NC_003155.4 5280601 5281674 R PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; partitioning or sporulation protein complement(5280601..5281674) Streptomyces avermitilis MA-4680 1210942 NP_825487.1 CDS gidB NC_003155.4 5281976 5282716 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(5281976..5282716) Streptomyces avermitilis MA-4680 1210943 NP_825488.1 CDS jag NC_003155.4 5282854 5283366 R Jag-like protein complement(5282854..5283366) Streptomyces avermitilis MA-4680 1210944 NP_825489.1 CDS SAV_4312 NC_003155.4 5283382 5284668 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC complement(5283382..5284668) Streptomyces avermitilis MA-4680 1215177 NP_825490.1 CDS SAV_4313 NC_003155.4 5284672 5285025 R PF01809: Domain of unknown function DUF37; hypothetical protein complement(5284672..5285025) Streptomyces avermitilis MA-4680 1215178 NP_825491.1 CDS rnpA NC_003155.4 5285022 5285393 R PF00825: Ribonuclease P; RNase P component complement(5285022..5285393) Streptomyces avermitilis MA-4680 1210945 NP_825492.1 CDS rpmH NC_003155.4 5285412 5285549 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(5285412..5285549) Streptomyces avermitilis MA-4680 1210946 NP_825493.1 CDS dnaA NC_003155.4 5285972 5287933 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 5285972..5287933 Streptomyces avermitilis MA-4680 1210947 NP_825494.1 CDS dnaN1 NC_003155.4 5289024 5290154 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 5289024..5290154 Streptomyces avermitilis MA-4680 1210948 NP_825495.1 CDS gnd2 NC_003155.4 5290374 5291249 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 5290374..5291249 Streptomyces avermitilis MA-4680 1210949 NP_825496.1 CDS recF NC_003155.4 5291312 5292433 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5291312..5292433 Streptomyces avermitilis MA-4680 1210950 NP_825497.1 CDS SAV_4320 NC_003155.4 5292430 5292975 D PF05258: Protein of unknown function (DUF721); hypothetical protein 5292430..5292975 Streptomyces avermitilis MA-4680 1215179 NP_825498.1 CDS gyrB NC_003155.4 5293712 5295790 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 5293712..5295790 Streptomyces avermitilis MA-4680 1210951 NP_825499.1 CDS gyrA NC_003155.4 5295833 5298427 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 5295833..5298427 Streptomyces avermitilis MA-4680 1210952 NP_825500.1 CDS SAV_4323 NC_003155.4 5298567 5299181 D hypothetical protein 5298567..5299181 Streptomyces avermitilis MA-4680 1215180 NP_825501.1 CDS SAV_4324 NC_003155.4 5299713 5300060 R hypothetical protein complement(5299713..5300060) Streptomyces avermitilis MA-4680 1215181 NP_825502.1 CDS SAV_4325 NC_003155.4 5300774 5302279 D hypothetical protein 5300774..5302279 Streptomyces avermitilis MA-4680 1215182 NP_825503.1 CDS pkn10 NC_003155.4 5302280 5303974 R serine/threonine protein kinase complement(5302280..5303974) Streptomyces avermitilis MA-4680 1210954 NP_825504.1 CDS SAV_4327 NC_003155.4 5304174 5304722 R DNA-binding protein complement(5304174..5304722) Streptomyces avermitilis MA-4680 1215183 NP_825505.1 CDS SAV_4328 NC_003155.4 5305386 5306087 R regulatory protein complement(5305386..5306087) Streptomyces avermitilis MA-4680 1215184 NP_825506.1 CDS ppiA NC_003155.4 5306491 5307051 D peptidyl-prolyl cis-trans isomerase 5306491..5307051 Streptomyces avermitilis MA-4680 1210956 NP_825507.1 CDS SAV_4330 NC_003155.4 5307277 5308173 D PF01694: Rhomboid family; hypothetical protein 5307277..5308173 Streptomyces avermitilis MA-4680 1215185 NP_825508.1 CDS whiP NC_003155.4 5308456 5308710 R integral membrane protein involved in inhibition of the Z-ring formation; putative septation inhibitor protein complement(5308456..5308710) Streptomyces avermitilis MA-4680 1210957 NP_825509.1 CDS SAV_4332 NC_003155.4 5308853 5309665 D PF05949: Bacterial protein of unknown function (DUF881); hypothetical protein 5308853..5309665 Streptomyces avermitilis MA-4680 1215186 NP_825510.1 CDS SAV_4333 NC_003155.4 5309712 5310404 D PF04203: sortase family; hypothetical protein 5309712..5310404 Streptomyces avermitilis MA-4680 1215187 NP_825511.1 CDS SAV_4334 NC_003155.4 5310409 5310597 D hypothetical protein 5310409..5310597 Streptomyces avermitilis MA-4680 1215188 NP_825512.1 CDS pabA NC_003155.4 5310594 5311232 D aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 5310594..5311232 Streptomyces avermitilis MA-4680 1210958 NP_825513.1 CDS SAV_4336 NC_003155.4 5311229 5312578 D PF04203: sortase family; hypothetical protein 5311229..5312578 Streptomyces avermitilis MA-4680 1215189 NP_825514.1 CDS SAV_4337 NC_003155.4 5312592 5313332 D PF04203: sortase family; hypothetical protein 5312592..5313332 Streptomyces avermitilis MA-4680 1215190 NP_825515.1 CDS pkn11 NC_003155.4 5313395 5315398 R serine/threonine protein kinase complement(5313395..5315398) Streptomyces avermitilis MA-4680 1210959 NP_825516.1 CDS pbp6 NC_003155.4 5315569 5317053 R PF00905: Penicillin binding protein transpeptidase domain; penicillin-binding protein complement(5315569..5317053) Streptomyces avermitilis MA-4680 1210960 NP_825517.1 CDS ftsW3 NC_003155.4 5317050 5318498 R PF01098: Cell cycle protein; cell division membrane protein complement(5317050..5318498) Streptomyces avermitilis MA-4680 1210961 NP_825518.1 CDS prpB8 NC_003155.4 5318525 5320069 R PF00481: Protein phosphatase 2C; magnesium or manganese-dependent protein phosphatase complement(5318525..5320069) Streptomyces avermitilis MA-4680 1215191 NP_825519.1 CDS SAV_4342 NC_003155.4 5320190 5320717 R PF00498: FHA domain; hypothetical protein complement(5320190..5320717) Streptomyces avermitilis MA-4680 1215192 NP_825520.1 CDS SAV_4343 NC_003155.4 5320728 5321585 R PF00498: FHA domain; hypothetical protein complement(5320728..5321585) Streptomyces avermitilis MA-4680 1215193 NP_825521.1 CDS acpD NC_003155.4 5322321 5322974 R ACP phosphodiesterase complement(5322321..5322974) Streptomyces avermitilis MA-4680 1215194 NP_825522.1 CDS SAV_4345 NC_003155.4 5323110 5323517 D PF01638: Transcriptional regulator; transcriptional regulator 5323110..5323517 Streptomyces avermitilis MA-4680 1215195 NP_825523.1 CDS SAV_4346 NC_003155.4 5323799 5325265 D hypothetical protein 5323799..5325265 Streptomyces avermitilis MA-4680 1215196 NP_825524.1 CDS SAV_4347 NC_003155.4 5325561 5326400 D PF00226: DnaJ domain; hypothetical protein 5325561..5326400 Streptomyces avermitilis MA-4680 1215197 NP_825525.1 CDS SAV_4348 NC_003155.4 5326463 5326792 D PF00581: Rhodanese-like domain; hypothetical protein 5326463..5326792 Streptomyces avermitilis MA-4680 1215198 NP_825526.1 CDS fadE19 NC_003155.4 5326971 5328110 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(5326971..5328110) Streptomyces avermitilis MA-4680 1210963 NP_825527.1 CDS paaE NC_003155.4 5328286 5329350 R phenylacetate catabolism; phenylacetic acid degradation NADH oxidoreductase complement(5328286..5329350) Streptomyces avermitilis MA-4680 1210964 NP_825528.1 CDS paaD NC_003155.4 5329350 5329862 R phenylacetate catabolism; phenylacetic acid degradation protein complement(5329350..5329862) Streptomyces avermitilis MA-4680 1210965 NP_825529.1 CDS paaC NC_003155.4 5329907 5330626 R phenylacetate catabolism; phenylacetic acid degradation protein complement(5329907..5330626) Streptomyces avermitilis MA-4680 1210966 NP_825530.1 CDS paaB NC_003155.4 5330623 5330910 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB complement(5330623..5330910) Streptomyces avermitilis MA-4680 1210967 NP_825531.1 CDS paaA NC_003155.4 5330912 5331931 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA complement(5330912..5331931) Streptomyces avermitilis MA-4680 1210968 NP_825532.1 CDS SAV_4355 NC_003155.4 5332122 5333153 D hypothetical protein 5332122..5333153 Streptomyces avermitilis MA-4680 1215199 NP_825533.1 CDS SAV_4356 NC_003155.4 5333153 5334382 D hypothetical protein 5333153..5334382 Streptomyces avermitilis MA-4680 1215200 NP_825534.1 CDS tsnR1 NC_003155.4 5334379 5335128 D PF00588: SpoU rRNA Methylase family; rRNA methyltransferase 5334379..5335128 Streptomyces avermitilis MA-4680 1215201 NP_825535.1 CDS paaZ NC_003155.4 5335144 5336835 R phenylacetate catabolism; dehydrogenase complement(5335144..5336835) Streptomyces avermitilis MA-4680 1210969 NP_825536.1 CDS paaH NC_003155.4 5336984 5338498 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxy-acyl-CoA dehydrogenase 5336984..5338498 Streptomyces avermitilis MA-4680 1210970 NP_825537.1 CDS SAV_4360 NC_003155.4 5338495 5339085 D TetR family transcriptional regulator 5338495..5339085 Streptomyces avermitilis MA-4680 1215202 NP_825538.1 CDS SAV_4361 NC_003155.4 5339088 5339495 R transcription regulator AsnC complement(5339088..5339495) Streptomyces avermitilis MA-4680 1215203 NP_825539.1 CDS bkdA NC_003155.4 5339763 5340908 D 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-alpha chain 5339763..5340908 Streptomyces avermitilis MA-4680 1210971 NP_825540.1 CDS bkdB NC_003155.4 5340982 5341986 D 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-beta chain 5340982..5341986 Streptomyces avermitilis MA-4680 1210972 NP_825541.1 CDS bkdC NC_003155.4 5341986 5343353 D branched-chain alpha-keto acid dehydrogenase subunit E2 5341986..5343353 Streptomyces avermitilis MA-4680 1210973 NP_825542.1 CDS mobA NC_003155.4 5343429 5344316 D molybdopterin-guanine dinucleotide biosynthesis protein 5343429..5344316 Streptomyces avermitilis MA-4680 1210974 NP_825543.1 CDS moaA2 NC_003155.4 5344379 5345773 D molybdopterin biosynthesis protein 5344379..5345773 Streptomyces avermitilis MA-4680 1210975 NP_825544.1 CDS SAV_4367 NC_003155.4 5345833 5346867 D PF02254: TrkA-N domain; hypothetical protein 5345833..5346867 Streptomyces avermitilis MA-4680 1215204 NP_825545.1 CDS qor NC_003155.4 5346952 5347932 D PF00107: Zinc-binding dehydrogenase; quinone oxidoreductase 5346952..5347932 Streptomyces avermitilis MA-4680 1210976 NP_825546.1 CDS SAV_4369 NC_003155.4 5347961 5348923 R hypothetical protein complement(5347961..5348923) Streptomyces avermitilis MA-4680 1215205 NP_825547.1 CDS SAV_4370 NC_003155.4 5348987 5349532 D hypothetical protein 5348987..5349532 Streptomyces avermitilis MA-4680 1215206 NP_825548.1 CDS pkn12 NC_003155.4 5349704 5351356 R serine/threonine protein kinase complement(5349704..5351356) Streptomyces avermitilis MA-4680 1210977 NP_825549.1 CDS pkn13 NC_003155.4 5351732 5353231 D serine/threonine protein kinase 5351732..5353231 Streptomyces avermitilis MA-4680 1210978 NP_825550.1 CDS SAV_4373 NC_003155.4 5353436 5354485 R PF01636: Phosphotransferase enzyme family; hypothetical protein complement(5353436..5354485) Streptomyces avermitilis MA-4680 1215207 NP_825551.1 CDS SAV_4374 NC_003155.4 5354574 5355068 R hypothetical protein complement(5354574..5355068) Streptomyces avermitilis MA-4680 1215208 NP_825552.1 CDS SAV_4375 NC_003155.4 5355231 5355890 R two-component system response regulator complement(5355231..5355890) Streptomyces avermitilis MA-4680 1215209 NP_825553.1 CDS bkdF NC_003155.4 5356305 5357525 D branched-chain alpha keto acid dehydrogenase E1 alpha subunit 5356305..5357525 Streptomyces avermitilis MA-4680 1210979 NP_825554.1 CDS bkdG NC_003155.4 5357527 5358504 D branched-chain alpha keto acid dehydrogenase E1 beta subunit 5357527..5358504 Streptomyces avermitilis MA-4680 1210980 NP_825555.1 CDS bkdH NC_003155.4 5358524 5359912 D branched-chain alpha-keto acid dehydrogenase subunit E2 5358524..5359912 Streptomyces avermitilis MA-4680 1210981 NP_825556.1 CDS dacD NC_003155.4 5359989 5360819 R PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase complement(5359989..5360819) Streptomyces avermitilis MA-4680 1210982 NP_825557.1 CDS SAV_4380 NC_003155.4 5361083 5361766 D GntR family transcriptional regulator 5361083..5361766 Streptomyces avermitilis MA-4680 1215210 NP_825558.1 CDS SAV_4381 NC_003155.4 5361763 5363109 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 5361763..5363109 Streptomyces avermitilis MA-4680 1215211 NP_825559.1 CDS SAV_4382 NC_003155.4 5363265 5364089 R hypothetical protein complement(5363265..5364089) Streptomyces avermitilis MA-4680 1215212 NP_825560.1 CDS SAV_4383 NC_003155.4 5364245 5365051 D PF00795: Carbon-nitrogen hydrolase; hydrolase 5364245..5365051 Streptomyces avermitilis MA-4680 1210983 NP_825561.1 CDS SAV_4384 NC_003155.4 5365119 5365613 R PF04525: Protein of unknown function (DUF567); hypothetical protein complement(5365119..5365613) Streptomyces avermitilis MA-4680 1215213 NP_825562.1 CDS SAV_4385 NC_003155.4 5365817 5366050 R hypothetical protein complement(5365817..5366050) Streptomyces avermitilis MA-4680 1215214 NP_825563.1 CDS SAV_4386 NC_003155.4 5366202 5367227 D frameshift, PF01436: NHL repeat; hypothetical protein 5366202..5367227 Streptomyces avermitilis MA-4680 1215215 NP_825564.1 CDS SAV_4387 NC_003155.4 5367136 5368020 D frameshift, PF01436: NHL repeat; hypothetical protein 5367136..5368020 Streptomyces avermitilis MA-4680 1215216 NP_825565.1 CDS SAV_4388 NC_003155.4 5368069 5368317 R hypothetical protein complement(5368069..5368317) Streptomyces avermitilis MA-4680 1215217 NP_825566.1 CDS SAV_4389 NC_003155.4 5368441 5369739 R catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2 complement(5368441..5369739) Streptomyces avermitilis MA-4680 1215218 NP_825567.1 CDS fadE24 NC_003155.4 5369895 5371721 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(5369895..5371721) Streptomyces avermitilis MA-4680 1210984 NP_825568.1 CDS SAV_4391 NC_003155.4 5371864 5372328 D hypothetical protein 5371864..5372328 Streptomyces avermitilis MA-4680 1215219 NP_825569.1 CDS SAV_4392 NC_003155.4 5372504 5373475 D PF02678: Pirin, phage attachment site is located in the coding region.; pirin-like protein 5372504..5373475 Streptomyces avermitilis MA-4680 1215220 NP_825570.1 CDS SAV_4393 NC_003155.4 5373665 5374708 D PF01594: Domain of unknown function DUF20; integral membrane protein 5373665..5374708 Streptomyces avermitilis MA-4680 1215221 NP_825571.1 CDS prpE3 NC_003155.4 5374725 5376869 R PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase complement(5374725..5376869) Streptomyces avermitilis MA-4680 1215222 NP_825572.1 CDS aspS NC_003155.4 5377024 5378787 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 5377024..5378787 Streptomyces avermitilis MA-4680 1210986 NP_825573.1 CDS SAV_4396 NC_003155.4 5378974 5379849 D PF00775: Dioxygenase; dioxygenase 5378974..5379849 Streptomyces avermitilis MA-4680 1215223 NP_825574.1 CDS SAV_4397 NC_003155.4 5379859 5380140 D hypothetical protein 5379859..5380140 Streptomyces avermitilis MA-4680 1215224 NP_825575.1 CDS SAV_4398 NC_003155.4 5380424 5380867 R regulatory protein complement(5380424..5380867) Streptomyces avermitilis MA-4680 1215225 NP_825576.1 CDS SAV_4399 NC_003155.4 5381111 5381959 D DNA-binding protein 5381111..5381959 Streptomyces avermitilis MA-4680 1215226 NP_825577.1 CDS SAV_4400 NC_003155.4 5382139 5382564 D hypothetical protein 5382139..5382564 Streptomyces avermitilis MA-4680 1215227 NP_825578.1 CDS SAV_4401 NC_003155.4 5382545 5383078 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(5382545..5383078) Streptomyces avermitilis MA-4680 1215228 NP_825579.1 CDS SAV_4402 NC_003155.4 5383149 5383634 R hypothetical protein complement(5383149..5383634) Streptomyces avermitilis MA-4680 1215229 NP_825580.1 CDS metS NC_003155.4 5383799 5385523 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(5383799..5385523) Streptomyces avermitilis MA-4680 1210987 NP_825581.1 CDS SAV_4404 NC_003155.4 5385730 5387478 R PF00092: von Willebrand factor type A domain; hypothetical protein complement(5385730..5387478) Streptomyces avermitilis MA-4680 1215230 NP_825582.1 CDS SAV_4405 NC_003155.4 5387779 5389881 D PF05787: Bacterial protein of unknown function (DUF839); hypothetical protein 5387779..5389881 Streptomyces avermitilis MA-4680 1215231 NP_825583.1 CDS SAV_4406 NC_003155.4 5389939 5390889 R LysR family transcriptional regulator complement(5389939..5390889) Streptomyces avermitilis MA-4680 1215232 NP_825584.1 CDS SAV_4407 NC_003155.4 5391097 5391780 D PF02031: Streptomyces extracellular neutral proteinase (M7) family; metalloprotease 5391097..5391780 Streptomyces avermitilis MA-4680 1215233 NP_825585.1 CDS SAV_4408 NC_003155.4 5391918 5393858 R PF05976: Bacterial membrane protein of unknown function (DUF893); integral membrane protein complement(5391918..5393858) Streptomyces avermitilis MA-4680 1215234 NP_825586.1 CDS SAV_4409 NC_003155.4 5393921 5394934 R PF03372: Endonuclease/Exonuclease/phosphatase family; hypothetical protein complement(5393921..5394934) Streptomyces avermitilis MA-4680 1215235 NP_825587.1 CDS SAV_4410 NC_003155.4 5395143 5395928 R PF00561: alpha/beta hydrolase fold; hydrolase complement(5395143..5395928) Streptomyces avermitilis MA-4680 1215236 NP_825588.1 CDS SAV_4411 NC_003155.4 5396010 5397446 D frameshift; GntR family transcriptional regulator 5396010..5397446 Streptomyces avermitilis MA-4680 1215237 NP_825589.1 CDS SAV_4412 NC_003155.4 5396629 5397363 D frameshift; transcriptional regulator 5396629..5397363 Streptomyces avermitilis MA-4680 1215238 NP_825590.1 CDS SAV_4413 NC_003155.4 5397278 5398177 R hypothetical protein complement(5397278..5398177) Streptomyces avermitilis MA-4680 1215239 NP_825591.1 CDS SAV_4414 NC_003155.4 5398569 5398967 R hypothetical protein complement(5398569..5398967) Streptomyces avermitilis MA-4680 1215240 NP_825592.1 CDS prpB9 NC_003155.4 5399204 5400463 D PF01933: Uncharacterised protein family UPF0052; membrane protein; magnesium or manganese-dependent protein phosphatase 5399204..5400463 Streptomyces avermitilis MA-4680 1215241 NP_825593.1 CDS SAV_4416 NC_003155.4 5400539 5401288 D two-component system response regulator 5400539..5401288 Streptomyces avermitilis MA-4680 1215242 NP_825594.1 CDS SAV_4417 NC_003155.4 5401291 5402415 D two-component system sensor kinase 5401291..5402415 Streptomyces avermitilis MA-4680 1215243 NP_825595.1 CDS SAV_4418 NC_003155.4 5402498 5403640 D hypothetical protein 5402498..5403640 Streptomyces avermitilis MA-4680 1215244 NP_825596.1 CDS SAV_4419 NC_003155.4 5403680 5405776 R hypothetical protein complement(5403680..5405776) Streptomyces avermitilis MA-4680 1215245 NP_825597.1 CDS SAV_4420 NC_003155.4 5405854 5406009 R hypothetical protein complement(5405854..5406009) Streptomyces avermitilis MA-4680 1215246 NP_825598.1 CDS SAV_4421 NC_003155.4 5406164 5407507 D regulatory protein 5406164..5407507 Streptomyces avermitilis MA-4680 1215247 NP_825599.1 CDS SAV_4422 NC_003155.4 5407822 5408043 R hypothetical protein complement(5407822..5408043) Streptomyces avermitilis MA-4680 1215248 NP_825600.1 CDS pbp7 NC_003155.4 5408114 5409736 R PF00912: Transglycosylase; penicillin-binding protein complement(5408114..5409736) Streptomyces avermitilis MA-4680 1210988 NP_825601.1 CDS SAV_4424 NC_003155.4 5409733 5410407 R hypothetical protein complement(5409733..5410407) Streptomyces avermitilis MA-4680 1215249 NP_825602.1 CDS sig38 NC_003155.4 5410404 5410841 R ECF subfamily RNA polymerase sigma factor complement(5410404..5410841) Streptomyces avermitilis MA-4680 1210989 NP_825603.1 CDS SAV_4426 NC_003155.4 5410838 5411599 R PF03734: ErfK/YbiS/YcfS/YnhG; hypothetical protein complement(5410838..5411599) Streptomyces avermitilis MA-4680 1215250 NP_825604.1 CDS sig39 NC_003155.4 5411790 5412317 D ECF subfamily RNA polymerase sigma factor 5411790..5412317 Streptomyces avermitilis MA-4680 1210990 NP_825605.1 CDS SAV_4428 NC_003155.4 5412370 5413092 D PF03734: ErfK/YbiS/YcfS/YnhG; hypothetical protein 5412370..5413092 Streptomyces avermitilis MA-4680 1215251 NP_825606.1 CDS SAV_4429 NC_003155.4 5413105 5413407 D hypothetical protein 5413105..5413407 Streptomyces avermitilis MA-4680 1215252 NP_825607.1 CDS SAV_4430 NC_003155.4 5413657 5414040 R hypothetical protein complement(5413657..5414040) Streptomyces avermitilis MA-4680 1215253 NP_825608.1 CDS SAV_4431 NC_003155.4 5414741 5415433 R hypothetical protein complement(5414741..5415433) Streptomyces avermitilis MA-4680 1215254 NP_825609.1 CDS SAV_4432 NC_003155.4 5415734 5418052 R PF00400: WD domain, G-beta repeat; beta transducin-like protein complement(5415734..5418052) Streptomyces avermitilis MA-4680 1215255 NP_825610.1 CDS SAV_4433 NC_003155.4 5418049 5420319 R hypothetical protein complement(5418049..5420319) Streptomyces avermitilis MA-4680 1215256 NP_825611.1 CDS SAV_4434 NC_003155.4 5420456 5421829 D PF02450: Lecithin:cholesterol acyltransferase; hypothetical protein 5420456..5421829 Streptomyces avermitilis MA-4680 1215257 NP_825612.1 CDS SAV_4435 NC_003155.4 5421978 5423018 D hypothetical protein 5421978..5423018 Streptomyces avermitilis MA-4680 1215258 NP_825613.1 CDS SAV_4436 NC_003155.4 5423150 5423887 R hypothetical protein complement(5423150..5423887) Streptomyces avermitilis MA-4680 1215259 NP_825614.1 CDS SAV_4437 NC_003155.4 5423925 5424692 D hypothetical protein 5423925..5424692 Streptomyces avermitilis MA-4680 1215260 NP_825615.1 CDS SAV_4438 NC_003155.4 5424902 5425672 D hypothetical protein 5424902..5425672 Streptomyces avermitilis MA-4680 1215261 NP_825616.1 CDS SAV_4439 NC_003155.4 5425825 5426880 D permease 5425825..5426880 Streptomyces avermitilis MA-4680 1215262 NP_825617.1 CDS SAV_4440 NC_003155.4 5426832 5427671 D hypothetical protein 5426832..5427671 Streptomyces avermitilis MA-4680 1215263 NP_825618.1 CDS SAV_4441 NC_003155.4 5427739 5428461 R hypothetical protein complement(5427739..5428461) Streptomyces avermitilis MA-4680 1215264 NP_825619.1 CDS SAV_4442 NC_003155.4 5428474 5429163 D hypothetical protein 5428474..5429163 Streptomyces avermitilis MA-4680 1215265 NP_825620.2 CDS SAV_4443 NC_003155.4 5429180 5430301 R IS630 family transposase complement(5429180..5430301) Streptomyces avermitilis MA-4680 1215266 NP_825621.1 CDS SAV_4444 NC_003155.4 5430439 5431380 D PF00702: haloacid dehalogenase-like hydrolase; hypothetical protein 5430439..5431380 Streptomyces avermitilis MA-4680 1215267 NP_825622.1 CDS SAV_4445 NC_003155.4 5431462 5431839 R hypothetical protein complement(5431462..5431839) Streptomyces avermitilis MA-4680 1215268 NP_825623.1 CDS SAV_4446 NC_003155.4 5431916 5433448 R PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase complement(5431916..5433448) Streptomyces avermitilis MA-4680 1215269 NP_825624.1 CDS cspD4 NC_003155.4 5433840 5434043 R cold shock protein complement(5433840..5434043) Streptomyces avermitilis MA-4680 1210991 NP_825625.1 CDS SAV_4448 NC_003155.4 5434404 5434748 R MarR family transcriptional regulator complement(5434404..5434748) Streptomyces avermitilis MA-4680 1215270 NP_825626.1 CDS SAV_4449 NC_003155.4 5435200 5435382 R hypothetical protein complement(5435200..5435382) Streptomyces avermitilis MA-4680 1215271 NP_825627.1 CDS SAV_4450 NC_003155.4 5435482 5435955 D hypothetical protein 5435482..5435955 Streptomyces avermitilis MA-4680 1215272 NP_825628.1 CDS SAV_4451 NC_003155.4 5436036 5436461 D hypothetical protein 5436036..5436461 Streptomyces avermitilis MA-4680 1215273 NP_825629.1 CDS blaA3 NC_003155.4 5436525 5437490 D PF00144: Beta-lactamase; beta-lactamase 5436525..5437490 Streptomyces avermitilis MA-4680 1210992 NP_825630.1 CDS SAV_4453 NC_003155.4 5437523 5438674 D two-component system sensor kinase 5437523..5438674 Streptomyces avermitilis MA-4680 1215274 NP_825631.1 CDS SAV_4454 NC_003155.4 5438671 5439321 D two-component system response regulator 5438671..5439321 Streptomyces avermitilis MA-4680 1215275 NP_825632.1 CDS SAV_4455 NC_003155.4 5439435 5440601 D PF00144: Beta-lactamase; beta-lactamase 5439435..5440601 Streptomyces avermitilis MA-4680 1215276 NP_825633.1 CDS SAV_4456 NC_003155.4 5440567 5440959 D hypothetical protein 5440567..5440959 Streptomyces avermitilis MA-4680 1215277 NP_825634.1 CDS SAV_4457 NC_003155.4 5440971 5442080 R PF06626: Protein of unknown function (DUF1152); hypothetical protein complement(5440971..5442080) Streptomyces avermitilis MA-4680 1215278 NP_825635.1 CDS SAV_4458 NC_003155.4 5442619 5442948 D hypothetical protein 5442619..5442948 Streptomyces avermitilis MA-4680 1215279 NP_825636.1 CDS SAV_4459 NC_003155.4 5443230 5444921 D PF01186: Lysyl oxidase; hypothetical protein 5443230..5444921 Streptomyces avermitilis MA-4680 1215280 NP_825637.1 CDS SAV_4460 NC_003155.4 5445508 5446695 D hypothetical protein 5445508..5446695 Streptomyces avermitilis MA-4680 1215281 NP_825638.1 CDS SAV_4461 NC_003155.4 5447060 5448367 R PF05257: CHAP domain; hypothetical protein complement(5447060..5448367) Streptomyces avermitilis MA-4680 1215282 NP_825639.1 CDS wbpA NC_003155.4 5449474 5450733 D PF03721: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase 5449474..5450733 Streptomyces avermitilis MA-4680 1215283 NP_825640.1 CDS SAV_4463 NC_003155.4 5451109 5452428 D similar to hyaluronate synthase, PF00535: Glycosyl transferase; glycosyl transferase 5451109..5452428 Streptomyces avermitilis MA-4680 1215284 NP_825641.1 CDS dcd NC_003155.4 5453354 5453929 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 5453354..5453929 Streptomyces avermitilis MA-4680 1210994 NP_825642.1 CDS gptA NC_003155.4 5453950 5454459 D purine phosphoribosyltransferase 5453950..5454459 Streptomyces avermitilis MA-4680 1210995 NP_825643.1 CDS SAV_4466 NC_003155.4 5455631 5456419 R IS1648-like transposase complement(5455631..5456419) Streptomyces avermitilis MA-4680 1215285 NP_825644.1 CDS SAV_4467 NC_003155.4 5456416 5457267 R rRNA methyltransferase complement(5456416..5457267) Streptomyces avermitilis MA-4680 1215286 NP_825645.1 CDS int11 NC_003155.4 5457668 5459101 R PF07508: Recombinase; integrase/recombinase complement(5457668..5459101) Streptomyces avermitilis MA-4680 1215287 NP_825646.1 CDS SAV_4469 NC_003155.4 5459306 5460319 R hypothetical protein complement(5459306..5460319) Streptomyces avermitilis MA-4680 1215288 NP_825647.1 CDS SAV_4470 NC_003155.4 5460393 5460908 R regulatory protein complement(5460393..5460908) Streptomyces avermitilis MA-4680 1215289 NP_825648.1 CDS SAV_4471 NC_003155.4 5460989 5461831 D PF01381: Helix-turn-helix; DNA-binding protein 5460989..5461831 Streptomyces avermitilis MA-4680 1215290 NP_825649.1 CDS SAV_4472 NC_003155.4 5461843 5462028 D PF04149: Domain of unknown function (DUF397); hypothetical protein 5461843..5462028 Streptomyces avermitilis MA-4680 1215291 NP_825650.1 CDS SAV_4473 NC_003155.4 5462069 5463505 R PF01839: FG-GAP repeat; integrin-like protein complement(5462069..5463505) Streptomyces avermitilis MA-4680 1215292 NP_825651.1 CDS SAV_4474 NC_003155.4 5463525 5464970 R PF01839: FG-GAP repeat; integrin-like protein complement(5463525..5464970) Streptomyces avermitilis MA-4680 1215293 NP_825652.1 CDS SAV_4475 NC_003155.4 5465049 5466422 R PF01839: FG-GAP repeat; integrin-like protein complement(5465049..5466422) Streptomyces avermitilis MA-4680 1215294 NP_825653.1 CDS SAV_4476 NC_003155.4 5466471 5467916 R PF01839: FG-GAP repeat; integrin-like protein complement(5466471..5467916) Streptomyces avermitilis MA-4680 1215295 NP_825654.1 CDS SAV_4477 NC_003155.4 5468142 5469623 R PF01839: FG-GAP repeat; integrin-like protein complement(5468142..5469623) Streptomyces avermitilis MA-4680 1215296 NP_825655.1 CDS SAV_4478 NC_003155.4 5469949 5471394 R PF01839: FG-GAP repeat; integrin-like protein complement(5469949..5471394) Streptomyces avermitilis MA-4680 1215297 NP_825656.1 CDS SAV_4479 NC_003155.4 5471488 5472954 R PF01839: FG-GAP repeat; integrin-like protein complement(5471488..5472954) Streptomyces avermitilis MA-4680 1215298 NP_825657.1 CDS SAV_4480 NC_003155.4 5473189 5473617 D hypothetical protein 5473189..5473617 Streptomyces avermitilis MA-4680 1215299 NP_825658.1 CDS SAV_4481 NC_003155.4 5473717 5475165 R PF02389: Cornifin (SPRR) family; hypothetical protein complement(5473717..5475165) Streptomyces avermitilis MA-4680 1215300 NP_825659.1 CDS SAV_4482 NC_003155.4 5475393 5477660 R iron-sulphur-binding reductase complement(5475393..5477660) Streptomyces avermitilis MA-4680 1215301 NP_825660.1 CDS SAV_4483 NC_003155.4 5477906 5478958 D PF00953: Glycosyl transferase; glycosyl transferase 5477906..5478958 Streptomyces avermitilis MA-4680 1215302 NP_825661.1 CDS dnaK NC_003155.4 5479054 5480922 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 5479054..5480922 Streptomyces avermitilis MA-4680 1210996 NP_825662.1 CDS grpE1 NC_003155.4 5480919 5481584 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 5480919..5481584 Streptomyces avermitilis MA-4680 1210997 NP_825663.1 CDS dnaJ1 NC_003155.4 5481621 5482811 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 5481621..5482811 Streptomyces avermitilis MA-4680 1210998 NP_825664.1 CDS hspR NC_003155.4 5482816 5483265 D repressor of dnaK operon; HspR protein 5482816..5483265 Streptomyces avermitilis MA-4680 1210999 NP_825665.1 CDS SAV_4488 NC_003155.4 5483746 5484882 D sugar ABC transporter substrate-binding protein 5483746..5484882 Streptomyces avermitilis MA-4680 1215303 NP_825666.1 CDS SAV_4489 NC_003155.4 5485086 5485415 R hypothetical protein complement(5485086..5485415) Streptomyces avermitilis MA-4680 1215304 NP_825667.1 CDS SAV_4490 NC_003155.4 5485460 5487214 R PF02467: Transcription factor WhiB; hypothetical protein complement(5485460..5487214) Streptomyces avermitilis MA-4680 1215305 NP_825668.1 CDS SAV_4491 NC_003155.4 5487162 5487797 R hypothetical protein complement(5487162..5487797) Streptomyces avermitilis MA-4680 1215306 NP_825669.1 CDS SAV_4492 NC_003155.4 5487794 5489026 R hypothetical protein complement(5487794..5489026) Streptomyces avermitilis MA-4680 1215307 NP_825670.1 CDS SAV_4493 NC_003155.4 5489023 5489739 R hypothetical protein complement(5489023..5489739) Streptomyces avermitilis MA-4680 1215308 NP_825671.1 CDS SAV_4494 NC_003155.4 5489669 5490298 R hypothetical protein complement(5489669..5490298) Streptomyces avermitilis MA-4680 1215309 NP_825672.1 CDS SAV_4495 NC_003155.4 5490512 5492782 R hypothetical protein complement(5490512..5492782) Streptomyces avermitilis MA-4680 1215310 NP_825673.1 CDS SAV_4496 NC_003155.4 5492823 5493341 R hypothetical protein complement(5492823..5493341) Streptomyces avermitilis MA-4680 1215311 NP_825674.1 CDS SAV_4497 NC_003155.4 5493352 5493963 R hypothetical protein complement(5493352..5493963) Streptomyces avermitilis MA-4680 1215312 NP_825675.1 CDS SAV_4498 NC_003155.4 5493999 5496983 R hypothetical protein complement(5493999..5496983) Streptomyces avermitilis MA-4680 1215313 NP_825676.1 CDS SAV_4499 NC_003155.4 5497036 5497533 R hypothetical protein complement(5497036..5497533) Streptomyces avermitilis MA-4680 1215314 NP_825677.1 CDS SAV_4500 NC_003155.4 5497575 5497841 R hypothetical protein complement(5497575..5497841) Streptomyces avermitilis MA-4680 1215315 NP_825678.1 CDS SAV_4502 NC_003155.4 5497917 5498972 R hypothetical protein complement(5497917..5498972) Streptomyces avermitilis MA-4680 1215316 NP_825679.1 CDS SAV_4501 NC_003155.4 5498944 5500545 D hypothetical protein 5498944..5500545 Streptomyces avermitilis MA-4680 1215317 NP_825680.1 CDS SAV_4503 NC_003155.4 5500576 5501205 D hypothetical protein 5500576..5501205 Streptomyces avermitilis MA-4680 1215318 NP_825681.1 CDS SAV_4504 NC_003155.4 5501202 5502227 D hypothetical protein 5501202..5502227 Streptomyces avermitilis MA-4680 1215319 NP_825682.1 CDS SAV_4505 NC_003155.4 5502224 5502604 D hypothetical protein 5502224..5502604 Streptomyces avermitilis MA-4680 1215320 NP_825683.1 CDS SAV_4506 NC_003155.4 5502822 5503505 D hypothetical protein 5502822..5503505 Streptomyces avermitilis MA-4680 1215321 NP_825684.1 CDS SAV_4507 NC_003155.4 5503513 5505618 D PF01551: Peptidase family M23; peptidase 5503513..5505618 Streptomyces avermitilis MA-4680 1215322 NP_825685.1 CDS SAV_4508 NC_003155.4 5505620 5507065 D PF01011: PQQ enzyme repeat; hypothetical protein 5505620..5507065 Streptomyces avermitilis MA-4680 1215323 NP_825686.1 CDS trsK NC_003155.4 5507102 5508832 D conjugative transfer gene complex protein 5507102..5508832 Streptomyces avermitilis MA-4680 1215324 NP_825687.1 CDS SAV_4510 NC_003155.4 5509973 5511187 D LuxR family transcriptional regulator 5509973..5511187 Streptomyces avermitilis MA-4680 1215325 NP_825688.1 CDS SAV_4511 NC_003155.4 5511232 5512215 R LuxR family transcriptional regulator complement(5511232..5512215) Streptomyces avermitilis MA-4680 1215326 NP_825689.1 CDS SAV_4512 NC_003155.4 5512530 5512865 D hypothetical protein 5512530..5512865 Streptomyces avermitilis MA-4680 1215327 NP_825690.1 CDS SAV_4513 NC_003155.4 5513048 5513464 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(5513048..5513464) Streptomyces avermitilis MA-4680 1215328 NP_825691.1 CDS clpB1 NC_003155.4 5513634 5516246 D ATPases with chaperone activity, PF07724: ATPase family associated with various cellular activities (AAA); ATP-dependent Clp protease 5513634..5516246 Streptomyces avermitilis MA-4680 1211000 NP_825692.1 CDS SAV_4515 NC_003155.4 5516519 5517046 D hypothetical protein 5516519..5517046 Streptomyces avermitilis MA-4680 1215329 NP_825693.1 CDS SAV_4516 NC_003155.4 5517068 5518279 R PF04188: Protein of unknown function (DUF409); hypothetical protein complement(5517068..5518279) Streptomyces avermitilis MA-4680 1215330 NP_825694.1 CDS dapC NC_003155.4 5518466 5519662 R aminotransferase complement(5518466..5519662) Streptomyces avermitilis MA-4680 1215331 NP_825695.1 CDS SAV_4518 NC_003155.4 5520607 5521125 D hypothetical protein 5520607..5521125 Streptomyces avermitilis MA-4680 1215332 NP_825696.1 CDS speE NC_003155.4 5521235 5522881 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 5521235..5522881 Streptomyces avermitilis MA-4680 1211001 NP_825697.1 CDS SAV_4520 NC_003155.4 5522997 5523929 D PF06240: Carbon monoxide dehydrogenase subunit G (CoxG); hypothetical protein 5522997..5523929 Streptomyces avermitilis MA-4680 1215333 NP_825698.1 CDS SAV_4521 NC_003155.4 5524053 5524841 D PF01263: Aldose 1-epimerase; hypothetical protein 5524053..5524841 Streptomyces avermitilis MA-4680 1215334 NP_825699.1 CDS pyrE NC_003155.4 5524875 5525423 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 5524875..5525423 Streptomyces avermitilis MA-4680 1211002 NP_825700.1 CDS fbaA NC_003155.4 5525590 5526612 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 5525590..5526612 Streptomyces avermitilis MA-4680 1211003 NP_825701.1 CDS SAV_4524 NC_003155.4 5526702 5528291 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 5526702..5528291 Streptomyces avermitilis MA-4680 1215335 NP_825702.1 CDS SAV_4525 NC_003155.4 5528433 5528846 D hypothetical protein 5528433..5528846 Streptomyces avermitilis MA-4680 1215336 NP_825703.1 CDS tdo NC_003155.4 5529052 5529897 D PF03301: Tryptophan 2,3-dioxygenase; tryptophan 2,3-dioxygenase 5529052..5529897 Streptomyces avermitilis MA-4680 1211004 NP_825704.1 CDS SAV_4527 NC_003155.4 5529890 5531074 D PF01053: Cys/Met metabolism PLP-dependent enzyme; hydrolase 5529890..5531074 Streptomyces avermitilis MA-4680 1215337 NP_825705.1 CDS SAV_4528 NC_003155.4 5531090 5531443 R hypothetical protein complement(5531090..5531443) Streptomyces avermitilis MA-4680 1215338 NP_825706.1 CDS SAV_4529 NC_003155.4 5531573 5533534 R PF00498: FHA domain; hypothetical protein complement(5531573..5533534) Streptomyces avermitilis MA-4680 1215339 NP_825707.1 CDS SAV_4530 NC_003155.4 5533682 5534287 R TetR family transcriptional regulator complement(5533682..5534287) Streptomyces avermitilis MA-4680 1215340 NP_825708.1 CDS SAV_4531 NC_003155.4 5534474 5535493 D lipase/esterase 5534474..5535493 Streptomyces avermitilis MA-4680 1215341 NP_825709.1 CDS SAV_4532 NC_003155.4 5535768 5536859 D PF06259: Domain of unknown function (DUF1023); hypothetical protein 5535768..5536859 Streptomyces avermitilis MA-4680 1215342 NP_825710.1 CDS SAV_4533 NC_003155.4 5536852 5538147 D PF01757: Acyltransferase family; hypothetical protein 5536852..5538147 Streptomyces avermitilis MA-4680 1215343 NP_825711.1 CDS SAV_4534 NC_003155.4 5538158 5539612 D two-component system sensor kinase 5538158..5539612 Streptomyces avermitilis MA-4680 1215344 NP_825712.1 CDS SAV_4535 NC_003155.4 5539727 5540401 D two-component system response regulator 5539727..5540401 Streptomyces avermitilis MA-4680 1215345 NP_825713.1 CDS SAV_4536 NC_003155.4 5540582 5541961 D two-component system sensor kinase 5540582..5541961 Streptomyces avermitilis MA-4680 1215346 NP_825714.1 CDS SAV_4537 NC_003155.4 5541958 5542632 D two-component system response regulator 5541958..5542632 Streptomyces avermitilis MA-4680 1215347 NP_825715.1 CDS SAV_4538 NC_003155.4 5543067 5543252 D PF04149: Domain of unknown function (DUF397); hypothetical protein 5543067..5543252 Streptomyces avermitilis MA-4680 1215348 NP_825716.1 CDS cyp20 NC_003155.4 5543376 5544593 D CYP107P2; cytochrome P450 5543376..5544593 Streptomyces avermitilis MA-4680 1211005 NP_825717.1 CDS SAV_4540 NC_003155.4 5544848 5546452 R ABC transporter permease complement(5544848..5546452) Streptomyces avermitilis MA-4680 1215349 NP_825718.1 CDS SAV_4541 NC_003155.4 5546449 5547363 R ABC transporter ATP-binding protein complement(5546449..5547363) Streptomyces avermitilis MA-4680 1215350 NP_825719.1 CDS SAV_4542 NC_003155.4 5547552 5547962 D PF01047: MarR family; hypothetical protein 5547552..5547962 Streptomyces avermitilis MA-4680 1215351 NP_825720.1 CDS SAV_4543 NC_003155.4 5548088 5549590 R amino acid permease complement(5548088..5549590) Streptomyces avermitilis MA-4680 1215352 NP_825721.1 CDS eutB NC_003155.4 5549845 5551239 D ethanolamine ammonia-lyase large subunit 5549845..5551239 Streptomyces avermitilis MA-4680 1211006 NP_825722.1 CDS eutC NC_003155.4 5551236 5552024 D catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 5551236..5552024 Streptomyces avermitilis MA-4680 1211007 NP_825723.1 CDS SAV_4546 NC_003155.4 5552317 5553174 R hypothetical protein complement(5552317..5553174) Streptomyces avermitilis MA-4680 1215353 NP_825724.1 CDS purA NC_003155.4 5553370 5554653 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5553370..5554653 Streptomyces avermitilis MA-4680 1211008 NP_825725.1 CDS SAV_4548 NC_003155.4 5554881 5555531 R hypothetical protein complement(5554881..5555531) Streptomyces avermitilis MA-4680 1215354 NP_825726.1 CDS SAV_4549 NC_003155.4 5555606 5558074 R PF00535: Glycosyl transferase; glycosyl transferase complement(5555606..5558074) Streptomyces avermitilis MA-4680 1215355 NP_825727.1 CDS SAV_4550 NC_003155.4 5558071 5558775 R GntR family transcriptional regulator complement(5558071..5558775) Streptomyces avermitilis MA-4680 1215356 NP_825728.1 CDS SAV_4551 NC_003155.4 5558978 5560333 R hypothetical protein complement(5558978..5560333) Streptomyces avermitilis MA-4680 1215357 NP_825729.1 CDS SAV_4552 NC_003155.4 5560534 5561136 D PF01965: DJ-1/PfpI family; hypothetical protein 5560534..5561136 Streptomyces avermitilis MA-4680 1215358 NP_825730.1 CDS SAV_4553 NC_003155.4 5561133 5561588 D MarR family transcriptional regulator 5561133..5561588 Streptomyces avermitilis MA-4680 1215359 NP_825731.1 CDS pkn14 NC_003155.4 5561678 5563726 D serine/threonine protein kinase 5561678..5563726 Streptomyces avermitilis MA-4680 1211009 NP_825732.1 CDS SAV_4555 NC_003155.4 5563845 5564591 R hypothetical protein complement(5563845..5564591) Streptomyces avermitilis MA-4680 1215360 NP_825733.1 CDS SAV_4556 NC_003155.4 5564945 5565286 D PF02575: Uncharacterised BCR, YbaB family COG0718; hypothetical protein 5564945..5565286 Streptomyces avermitilis MA-4680 1215361 NP_825734.1 CDS recR NC_003155.4 5565399 5565998 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 5565399..5565998 Streptomyces avermitilis MA-4680 1211010 NP_825735.1 CDS SAV_4558 NC_003155.4 5565991 5566650 D hypothetical protein 5565991..5566650 Streptomyces avermitilis MA-4680 1215362 NP_825736.1 CDS lysC NC_003155.4 5567003 5568295 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 5567003..5568295 Streptomyces avermitilis MA-4680 1211011 NP_825737.1 CDS asd1 NC_003155.4 5568295 5569371 D aspartate-semialdehyde dehydrogenase 5568295..5569371 Streptomyces avermitilis MA-4680 1211012 NP_825738.1 CDS sig40 NC_003155.4 5569855 5570430 D ECF subfamily RNA polymerase sigma factor 5569855..5570430 Streptomyces avermitilis MA-4680 1211013 NP_825739.1 CDS SAV_4562 NC_003155.4 5570427 5571629 D hypothetical protein 5570427..5571629 Streptomyces avermitilis MA-4680 1215363 NP_825740.1 CDS SAV_4563 NC_003155.4 5571715 5572542 R hypothetical protein complement(5571715..5572542) Streptomyces avermitilis MA-4680 1215364 NP_825741.1 CDS SAV_4564 NC_003155.4 5572719 5574560 R PF00326: Prolyl oligopeptidase family; peptidase complement(5572719..5574560) Streptomyces avermitilis MA-4680 1215365 NP_825742.1 CDS SAV_4565 NC_003155.4 5574683 5576704 R PF02254: TrkA-N domain; hypothetical protein complement(5574683..5576704) Streptomyces avermitilis MA-4680 1215366 NP_825743.1 CDS SAV_4566 NC_003155.4 5576837 5577484 R PF01638: Transcriptional regulator; hypothetical protein complement(5576837..5577484) Streptomyces avermitilis MA-4680 1215367 NP_825744.1 CDS SAV_4567 NC_003155.4 5577789 5578559 R hypothetical protein complement(5577789..5578559) Streptomyces avermitilis MA-4680 1215368 NP_825745.1 CDS SAV_4568 NC_003155.4 5578556 5579566 R permease complement(5578556..5579566) Streptomyces avermitilis MA-4680 1215369 NP_825746.1 CDS SAV_4569 NC_003155.4 5579758 5581179 R hypothetical protein complement(5579758..5581179) Streptomyces avermitilis MA-4680 1215370 NP_825747.1 CDS SAV_4570 NC_003155.4 5581246 5582550 D PF00174: Oxidoreductase molybdopterin binding domain; hypothetical protein 5581246..5582550 Streptomyces avermitilis MA-4680 1215371 NP_825748.1 CDS SAV_4571 NC_003155.4 5582954 5583853 R PF05724: Thiopurine S-methyltransferase (TPMT); hypothetical protein complement(5582954..5583853) Streptomyces avermitilis MA-4680 1215372 NP_825749.1 CDS SAV_4572 NC_003155.4 5583850 5584467 R hypothetical protein complement(5583850..5584467) Streptomyces avermitilis MA-4680 1215373 NP_825750.1 CDS SAV_4573 NC_003155.4 5584464 5585261 R glycosyltransferase complement(5584464..5585261) Streptomyces avermitilis MA-4680 1215374 NP_825751.1 CDS galE2 NC_003155.4 5585503 5586504 R UDP-glucose 4-epimerase complement(5585503..5586504) Streptomyces avermitilis MA-4680 1211014 NP_825752.1 CDS SAV_4575 NC_003155.4 5586743 5588008 R PF00082: Subtilase family; serine protease complement(5586743..5588008) Streptomyces avermitilis MA-4680 1215375 NP_825753.1 CDS SAV_4576 NC_003155.4 5588005 5589681 R hypothetical protein complement(5588005..5589681) Streptomyces avermitilis MA-4680 1215376 NP_825754.1 CDS SAV_4577 NC_003155.4 5589742 5590305 R hypothetical protein complement(5589742..5590305) Streptomyces avermitilis MA-4680 1215377 NP_825755.1 CDS SAV_4578 NC_003155.4 5590803 5591261 D hypothetical protein 5590803..5591261 Streptomyces avermitilis MA-4680 1215378 NP_825756.1 CDS SAV_4579 NC_003155.4 5591261 5593192 D PF06259: Domain of unknown function (DUF1023); hypothetical protein 5591261..5593192 Streptomyces avermitilis MA-4680 1215379 NP_825757.1 CDS SAV_4580 NC_003155.4 5594588 5595373 R hypothetical protein complement(5594588..5595373) Streptomyces avermitilis MA-4680 1215380 NP_825758.1 CDS SAV_4581 NC_003155.4 5595461 5596387 R PF00149: Calcineurin-like phosphoesterase; hypothetical protein complement(5595461..5596387) Streptomyces avermitilis MA-4680 1215381 NP_825759.1 CDS SAV_4582 NC_003155.4 5596519 5596986 D PF02637: GatB/Yqey domain; hypothetical protein 5596519..5596986 Streptomyces avermitilis MA-4680 1215382 NP_825760.1 CDS pbp8 NC_003155.4 5597046 5599337 R PF00912: Transglycosylase; penicillin-binding protein complement(5597046..5599337) Streptomyces avermitilis MA-4680 1211016 NP_825761.1 CDS wblA NC_003155.4 5599696 5600085 D PF02467: Transcription factor WhiB; WhiB-family transcriptional regulator 5599696..5600085 Streptomyces avermitilis MA-4680 1211017 NP_825762.1 CDS SAV_4585 NC_003155.4 5600160 5601584 R PF02374: Anion-transporting ATPase; ion-transporting ATPase complement(5600160..5601584) Streptomyces avermitilis MA-4680 1215383 NP_825763.1 CDS SAV_4586 NC_003155.4 5601581 5602558 R PF02374: Anion-transporting ATPase; ion-transporting ATPase complement(5601581..5602558) Streptomyces avermitilis MA-4680 1215384 NP_825764.1 CDS SAV_4587 NC_003155.4 5602654 5602815 D hypothetical protein 5602654..5602815 Streptomyces avermitilis MA-4680 1215385 NP_825765.1 CDS SAV_4588 NC_003155.4 5602812 5603282 D PF01042: Endoribonuclease L-PSP; hypothetical protein 5602812..5603282 Streptomyces avermitilis MA-4680 1215386 NP_825766.1 CDS SAV_4589 NC_003155.4 5603487 5604359 D PF00293: NUDIX domain; hypothetical protein 5603487..5604359 Streptomyces avermitilis MA-4680 1215387 NP_825767.1 CDS SAV_4590 NC_003155.4 5604356 5605186 D PF00753: Metallo-beta-lactamase superfamily; hydrolase 5604356..5605186 Streptomyces avermitilis MA-4680 1215388 NP_825768.1 CDS SAV_4591 NC_003155.4 5605260 5606171 R PF01909: Nucleotidyltransferase domain; hypothetical protein complement(5605260..5606171) Streptomyces avermitilis MA-4680 1215389 NP_825769.1 CDS SAV_4592 NC_003155.4 5606198 5606872 R transcriptional regulator complement(5606198..5606872) Streptomyces avermitilis MA-4680 1215390 NP_825770.1 CDS nth NC_003155.4 5607216 5608148 D endonuclease III 5607216..5608148 Streptomyces avermitilis MA-4680 1211018 NP_825771.1 CDS SAV_4594 NC_003155.4 5608210 5608977 D PF00293: NUDIX domain; hypothetical protein 5608210..5608977 Streptomyces avermitilis MA-4680 1215391 NP_825772.1 CDS SAV_4595 NC_003155.4 5609098 5610297 D PF00089: Trypsin; serine protease 5609098..5610297 Streptomyces avermitilis MA-4680 1215392 NP_825773.1 CDS SAV_4596 NC_003155.4 5610647 5611597 R PF00561: alpha/beta hydrolase fold; hydrolase complement(5610647..5611597) Streptomyces avermitilis MA-4680 1215393 NP_825774.1 CDS SAV_4597 NC_003155.4 5611594 5612070 R PF07332: Protein of unknown function (DUF1469); hypothetical protein complement(5611594..5612070) Streptomyces avermitilis MA-4680 1215394 NP_825775.1 CDS nhaA NC_003155.4 5612114 5613514 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(5612114..5613514) Streptomyces avermitilis MA-4680 1215395 NP_825776.1 CDS acsA1 NC_003155.4 5613747 5615705 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(5613747..5615705) Streptomyces avermitilis MA-4680 1211019 NP_825777.1 CDS SAV_4600 NC_003155.4 5616032 5618407 R PF00916: Sulfate transporter family; hypothetical protein complement(5616032..5618407) Streptomyces avermitilis MA-4680 1215396 NP_825778.1 CDS SAV_4601 NC_003155.4 5618725 5619996 D hypothetical protein 5618725..5619996 Streptomyces avermitilis MA-4680 1215397 NP_825779.1 CDS cooC NC_003155.4 5619986 5620975 R PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; carbon monoxide dehydrogenase accessory protein complement(5619986..5620975) Streptomyces avermitilis MA-4680 1215398 NP_825780.1 CDS SAV_4603 NC_003155.4 5621068 5621892 D hypothetical protein 5621068..5621892 Streptomyces avermitilis MA-4680 1215399 NP_825781.1 CDS ssgB NC_003155.4 5622286 5623119 R morphological differentiation-associated protein complement(5622286..5623119) Streptomyces avermitilis MA-4680 1215400 NP_825782.1 CDS minD2 NC_003155.4 5623699 5624793 D PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; septum site determining protein 5623699..5624793 Streptomyces avermitilis MA-4680 1211020 NP_825783.1 CDS SAV_4606 NC_003155.4 5624790 5626091 D PF00437: Type II/IV secretion system protein; hypothetical protein 5624790..5626091 Streptomyces avermitilis MA-4680 1215401 NP_825784.1 CDS SAV_4607 NC_003155.4 5626372 5627001 D PF00482: Bacterial type II secretion system protein F domain; hypothetical protein 5626372..5627001 Streptomyces avermitilis MA-4680 1215402 NP_825785.1 CDS SAV_4608 NC_003155.4 5626998 5627498 D hypothetical protein 5626998..5627498 Streptomyces avermitilis MA-4680 1215403 NP_825786.1 CDS SAV_4609 NC_003155.4 5627482 5627787 D hypothetical protein 5627482..5627787 Streptomyces avermitilis MA-4680 1215404 NP_825787.1 CDS SAV_4610 NC_003155.4 5627907 5628140 D hypothetical protein 5627907..5628140 Streptomyces avermitilis MA-4680 1215405 NP_825788.1 CDS SAV_4611 NC_003155.4 5628127 5628567 D hypothetical protein 5628127..5628567 Streptomyces avermitilis MA-4680 1215406 NP_825789.1 CDS SAV_4612 NC_003155.4 5628315 5629013 D hypothetical protein 5628315..5629013 Streptomyces avermitilis MA-4680 1215407 NP_825790.1 CDS SAV_4613 NC_003155.4 5629010 5631517 R PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase complement(5629010..5631517) Streptomyces avermitilis MA-4680 1215408 NP_825791.1 CDS rsbV NC_003155.4 5631598 5631939 D PF01740: STAS domain; anti-sigma factor antagonist 5631598..5631939 Streptomyces avermitilis MA-4680 1211021 NP_825792.1 CDS SAV_4615 NC_003155.4 5632069 5632509 D anti-sigma factor 5632069..5632509 Streptomyces avermitilis MA-4680 1215409 NP_825793.1 CDS hppA NC_003155.4 5632824 5635229 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 5632824..5635229 Streptomyces avermitilis MA-4680 1215410 NP_825794.1 CDS SAV_4617 NC_003155.4 5635446 5636042 D hypothetical protein 5635446..5636042 Streptomyces avermitilis MA-4680 1215411 NP_825795.1 CDS SAV_4618 NC_003155.4 5636158 5637747 D rRNA or tRNA methyltransferase 5636158..5637747 Streptomyces avermitilis MA-4680 1215412 NP_825796.1 CDS pkn15 NC_003155.4 5637938 5640166 D serine/threonine protein kinase 5637938..5640166 Streptomyces avermitilis MA-4680 1211022 NP_825797.1 CDS SAV_4620 NC_003155.4 5640163 5640504 D hypothetical protein 5640163..5640504 Streptomyces avermitilis MA-4680 1215413 NP_825798.1 CDS topA NC_003155.4 5640787 5643615 D PF01131: DNA topoisomerase; DNA topoisomerase I 5640787..5643615 Streptomyces avermitilis MA-4680 1211023 NP_825799.1 CDS tmk NC_003155.4 5643834 5647055 D PF02223: Thymidylate kinase; thymidylate kinase 5643834..5647055 Streptomyces avermitilis MA-4680 1211024 NP_825800.1 CDS holB NC_003155.4 5647265 5648470 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 5647265..5648470 Streptomyces avermitilis MA-4680 1211025 NP_825801.1 CDS slpD NC_003155.4 5648606 5650207 D PF00561: alpha/beta hydrolase fold; protease 5648606..5650207 Streptomyces avermitilis MA-4680 1211026 NP_825802.1 CDS int12 NC_003155.4 5650089 5651111 R integrated tRNA gene, PF00589: Phage integrase family; integrase/recombinase complement(5650089..5651111) Streptomyces avermitilis MA-4680 1215414 NP_825803.1 CDS SAV_4625 NC_003155.4 5651093 5651473 D hypothetical protein 5651093..5651473 Streptomyces avermitilis MA-4680 1215415 NP_825804.1 CDS SAV_4627 NC_003155.4 5651778 5652002 R hypothetical protein complement(5651778..5652002) Streptomyces avermitilis MA-4680 1215416 NP_825805.1 CDS SAV_4628 NC_003155.4 5652810 5653526 R PF01590: GAF domain; hypothetical protein complement(5652810..5653526) Streptomyces avermitilis MA-4680 1215417 NP_825806.1 CDS SAV_4629 NC_003155.4 5653610 5654485 R PF03861: ANTAR domain; hypothetical protein complement(5653610..5654485) Streptomyces avermitilis MA-4680 1215418 NP_825807.1 CDS SAV_4630 NC_003155.4 5654485 5655219 R hypothetical protein complement(5654485..5655219) Streptomyces avermitilis MA-4680 1215419 NP_825808.1 CDS SAV_4631 NC_003155.4 5655894 5656178 R PF03861: ANTAR domain; hypothetical protein complement(5655894..5656178) Streptomyces avermitilis MA-4680 1215420 NP_825809.1 CDS SAV_4632 NC_003155.4 5656369 5656707 R hypothetical protein complement(5656369..5656707) Streptomyces avermitilis MA-4680 1215421 NP_825810.1 CDS SAV_4633 NC_003155.4 5657322 5657666 D hypothetical protein 5657322..5657666 Streptomyces avermitilis MA-4680 1215422 NP_825811.1 CDS SAV_4634 NC_003155.4 5658328 5659263 D glycosyltransferase 5658328..5659263 Streptomyces avermitilis MA-4680 1215423 NP_825812.1 CDS SAV_4635 NC_003155.4 5659480 5662893 D similar to AfsR, PF03704: Bacterial transcriptional activator domain; transcriptional regulator 5659480..5662893 Streptomyces avermitilis MA-4680 1215424 NP_825813.1 CDS polA2 NC_003155.4 5662853 5664547 R DNA polymerase I complement(5662853..5664547) Streptomyces avermitilis MA-4680 1211028 NP_825814.1 CDS clpX1 NC_003155.4 5664626 5665315 R ClpX protein complement(5664626..5665315) Streptomyces avermitilis MA-4680 1211029 NP_825815.1 CDS SAV_4638 NC_003155.4 5665530 5666657 D hypothetical protein 5665530..5666657 Streptomyces avermitilis MA-4680 1215425 NP_825816.1 CDS SAV_4639 NC_003155.4 5666668 5667186 R hypothetical protein complement(5666668..5667186) Streptomyces avermitilis MA-4680 1215426 NP_825817.1 CDS SAV_4640 NC_003155.4 5667649 5668158 R PF05481: Mycobacterium 19 kDa lipoprotein antigen; hypothetical protein complement(5667649..5668158) Streptomyces avermitilis MA-4680 1215427 NP_825818.1 CDS rpsN NC_003155.4 5668223 5668528 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(5668223..5668528) Streptomyces avermitilis MA-4680 1211030 NP_825819.1 CDS rpmB NC_003155.4 5668528 5668749 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(5668528..5668749) Streptomyces avermitilis MA-4680 1211031 NP_825820.1 CDS rpmG NC_003155.4 5668835 5668999 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 5668835..5668999 Streptomyces avermitilis MA-4680 1211032 NP_825821.1 CDS rpmE2 NC_003155.4 5669005 5669253 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 5669005..5669253 Streptomyces avermitilis MA-4680 1211033 NP_825822.1 CDS SAV_4645 NC_003155.4 5669258 5670601 D PF07683: Cobalamin synthesis protein cobW C-terminal domain; hypothetical protein 5669258..5670601 Streptomyces avermitilis MA-4680 1215428 NP_825823.1 CDS rpsR2 NC_003155.4 5670601 5670837 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5670601..5670837 Streptomyces avermitilis MA-4680 1211034 NP_825824.1 CDS SAV_4647 NC_003155.4 5671432 5671653 D regulatory protein 5671432..5671653 Streptomyces avermitilis MA-4680 1215429 NP_825825.1 CDS SAV_4648 NC_003155.4 5671774 5672298 R regulatory protein complement(5671774..5672298) Streptomyces avermitilis MA-4680 1215430 NP_825826.1 CDS SAV_4649 NC_003155.4 5672654 5673478 D DNA-binding protein 5672654..5673478 Streptomyces avermitilis MA-4680 1215431 NP_825827.1 CDS SAV_4650 NC_003155.4 5673611 5675071 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 5673611..5675071 Streptomyces avermitilis MA-4680 1215432 NP_825828.1 CDS SAV_4651 NC_003155.4 5675271 5675810 D PF04978: Protein of unknown function (DUF664); hypothetical protein 5675271..5675810 Streptomyces avermitilis MA-4680 1215433 NP_825829.1 CDS SAV_4652 NC_003155.4 5675835 5676476 D transcriptional regulator 5675835..5676476 Streptomyces avermitilis MA-4680 1215434 NP_825830.1 CDS SAV_4653 NC_003155.4 5676565 5677497 D ABC transporter ATP-binding protein 5676565..5677497 Streptomyces avermitilis MA-4680 1215435 NP_825831.1 CDS SAV_4654 NC_003155.4 5677515 5678276 D hypothetical protein 5677515..5678276 Streptomyces avermitilis MA-4680 1215436 NP_825832.1 CDS gadB2 NC_003155.4 5678301 5679713 R PF00282: Pyridoxal-dependent decarboxylase conserved domain; glutamate decarboxylase complement(5678301..5679713) Streptomyces avermitilis MA-4680 1211035 NP_825833.1 CDS SAV_4656 NC_003155.4 5679747 5681030 R PF00654: Voltage gated chloride channel; hypothetical protein complement(5679747..5681030) Streptomyces avermitilis MA-4680 1215437 NP_825834.1 CDS tipA NC_003155.4 5681130 5681891 D MerR family transcriptional regulator 5681130..5681891 Streptomyces avermitilis MA-4680 1211036 NP_825835.1 CDS SAV_4658 NC_003155.4 5681955 5682320 R PF01906: Domain of unknown function DUF74; hypothetical protein complement(5681955..5682320) Streptomyces avermitilis MA-4680 1215438 NP_825836.1 CDS SAV_4659 NC_003155.4 5682461 5683480 D PF00597: DedA family; hypothetical protein 5682461..5683480 Streptomyces avermitilis MA-4680 1215439 NP_825837.1 CDS SAV_4660 NC_003155.4 5683583 5685244 R PF06738: Protein of unknown function (DUF1212); hypothetical protein complement(5683583..5685244) Streptomyces avermitilis MA-4680 1215440 NP_825838.1 CDS ppa NC_003155.4 5685377 5685868 R inorganic pyrophosphatase complement(5685377..5685868) Streptomyces avermitilis MA-4680 1211037 NP_825839.1 CDS dacE NC_003155.4 5686245 5687630 D PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 5686245..5687630 Streptomyces avermitilis MA-4680 1215441 NP_825840.1 CDS SAV_4663 NC_003155.4 5687726 5688859 D hypothetical protein 5687726..5688859 Streptomyces avermitilis MA-4680 1215442 NP_825841.1 CDS mesJ NC_003155.4 5689055 5690092 D PF01171: PP-loop family; cell cycle protein 5689055..5690092 Streptomyces avermitilis MA-4680 1215443 NP_825842.1 CDS hprT NC_003155.4 5690146 5690706 D hypoxanthine phosphoribosyltransferase 5690146..5690706 Streptomyces avermitilis MA-4680 1211038 NP_825843.1 CDS ftsH NC_003155.4 5690937 5692931 D cell division protein FtsH 5690937..5692931 Streptomyces avermitilis MA-4680 1211039 NP_825844.1 CDS folE NC_003155.4 5693074 5693679 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 5693074..5693679 Streptomyces avermitilis MA-4680 1211040 NP_825845.1 CDS SAV_4668 NC_003155.4 5693728 5694216 R hypothetical protein complement(5693728..5694216) Streptomyces avermitilis MA-4680 1215444 NP_825846.1 CDS folK NC_003155.4 5694270 5694881 R folic acid biosynthesis; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(5694270..5694881) Streptomyces avermitilis MA-4680 1211041 NP_825847.1 CDS folX NC_003155.4 5694878 5695237 R folic acid biosynthesis; dihydroneopterin aldolase complement(5694878..5695237) Streptomyces avermitilis MA-4680 1211042 NP_825848.1 CDS SAV_4671 NC_003155.4 5695508 5696017 R hypothetical protein complement(5695508..5696017) Streptomyces avermitilis MA-4680 1215445 NP_825849.1 CDS folP2 NC_003155.4 5696014 5696946 R folic acid biosynthesis; dihydropteroate synthase complement(5696014..5696946) Streptomyces avermitilis MA-4680 1211043 NP_825850.1 CDS SAV_4673 NC_003155.4 5697154 5698959 R PF04329: Family of unknown function (DUF470); hypothetical protein complement(5697154..5698959) Streptomyces avermitilis MA-4680 1215446 NP_825851.1 CDS SAV_4674 NC_003155.4 5699189 5700319 D PF00756: Putative esterase; hypothetical protein 5699189..5700319 Streptomyces avermitilis MA-4680 1215447 NP_825852.1 CDS SAV_4675 NC_003155.4 5700632 5702176 D hypothetical protein 5700632..5702176 Streptomyces avermitilis MA-4680 1215448 NP_825853.1 CDS SAV_4676 NC_003155.4 5702276 5703649 R PF03703: Bacterial membrane flanked domain; hypothetical protein complement(5702276..5703649) Streptomyces avermitilis MA-4680 1215449 NP_825854.1 CDS SAV_4677 NC_003155.4 5703664 5704185 R PF03703: Bacterial membrane flanked domain; integral membrane protein complement(5703664..5704185) Streptomyces avermitilis MA-4680 1215450 NP_825855.1 CDS nuoD2 NC_003155.4 5704217 5705368 D NADH dehydrogenase I chain D 5704217..5705368 Streptomyces avermitilis MA-4680 1211044 NP_825856.1 CDS SAV_4679 NC_003155.4 5705333 5706391 R PF02636: Uncharacterized ACR, COG1565; hypothetical protein complement(5705333..5706391) Streptomyces avermitilis MA-4680 1215451 NP_825857.1 CDS SAV_4680 NC_003155.4 5706510 5707715 D two-component system sensor kinase 5706510..5707715 Streptomyces avermitilis MA-4680 1215452 NP_825858.1 CDS SAV_4681 NC_003155.4 5707796 5708467 D two-component system response regulator 5707796..5708467 Streptomyces avermitilis MA-4680 1215453 NP_825859.1 CDS SAV_4682 NC_003155.4 5708500 5709132 D TmrB-like protein 5708500..5709132 Streptomyces avermitilis MA-4680 1215454 NP_825860.1 CDS SAV_4683 NC_003155.4 5709139 5710263 R transcription regulator ArsR complement(5709139..5710263) Streptomyces avermitilis MA-4680 1215455 NP_825861.1 CDS SAV_4684 NC_003155.4 5710565 5710693 R hypothetical protein complement(5710565..5710693) Streptomyces avermitilis MA-4680 1215456 NP_825862.1 CDS SAV_4685 NC_003155.4 5710805 5712046 R L-allo-threonine aldolase complement(5710805..5712046) Streptomyces avermitilis MA-4680 1215457 NP_825863.1 CDS SAV_4686 NC_003155.4 5712219 5713139 D PF01210: NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; hypothetical protein 5712219..5713139 Streptomyces avermitilis MA-4680 1215458 NP_825864.1 CDS panC NC_003155.4 5713136 5714137 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 5713136..5714137 Streptomyces avermitilis MA-4680 1211045 NP_825865.1 CDS nadB NC_003155.4 5714134 5715951 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 5714134..5715951 Streptomyces avermitilis MA-4680 1211046 NP_825866.1 CDS nadC NC_003155.4 5715948 5716943 D catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 5715948..5716943 Streptomyces avermitilis MA-4680 1211047 NP_825867.1 CDS SAV_4690 NC_003155.4 5716953 5717750 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 5716953..5717750 Streptomyces avermitilis MA-4680 1215459 NP_825868.1 CDS SAV_4691 NC_003155.4 5718058 5718780 D hypothetical protein 5718058..5718780 Streptomyces avermitilis MA-4680 1215460 NP_825869.1 CDS SAV_4692 NC_003155.4 5718824 5719003 D hypothetical protein 5718824..5719003 Streptomyces avermitilis MA-4680 1215461 NP_825870.1 CDS SAV_4693 NC_003155.4 5719170 5719703 D hypothetical protein 5719170..5719703 Streptomyces avermitilis MA-4680 1215462 NP_825871.1 CDS SAV_4694 NC_003155.4 5719744 5720286 D catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 5719744..5720286 Streptomyces avermitilis MA-4680 1215463 NP_825872.1 CDS SAV_4695 NC_003155.4 5720536 5720871 D Lsr2-like protein 5720536..5720871 Streptomyces avermitilis MA-4680 1215464 NP_825873.1 CDS SAV_4696 NC_003155.4 5720850 5721551 R proline-rich protein complement(5720850..5721551) Streptomyces avermitilis MA-4680 1215465 NP_825874.1 CDS clpC2 NC_003155.4 5721983 5724508 D PF07724: ATPase family associated with various cellular activities (AAA); ATP-dependent Clp protease 5721983..5724508 Streptomyces avermitilis MA-4680 1211048 NP_825875.1 CDS SAV_4698 NC_003155.4 5724587 5727706 R large ATP-binding protein complement(5724587..5727706) Streptomyces avermitilis MA-4680 1215466 NP_825876.1 CDS SAV_4699 NC_003155.4 5727746 5728303 R hypothetical protein complement(5727746..5728303) Streptomyces avermitilis MA-4680 1215467 NP_825877.1 CDS SAV_4700 NC_003155.4 5728690 5729301 D PF01551: Peptidase family M23; peptidase 5728690..5729301 Streptomyces avermitilis MA-4680 1215468 NP_825878.1 CDS SAV_4701 NC_003155.4 5729317 5729892 R TetR family transcriptional regulator complement(5729317..5729892) Streptomyces avermitilis MA-4680 1215469 NP_825879.1 CDS SAV_4702 NC_003155.4 5730082 5731695 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 5730082..5731695 Streptomyces avermitilis MA-4680 1215470 NP_825880.1 CDS SAV_4703 NC_003155.4 5731882 5733345 R similar to AfsQ2; two-component system sensor kinase complement(5731882..5733345) Streptomyces avermitilis MA-4680 1215471 NP_825881.1 CDS SAV_4704 NC_003155.4 5733354 5734061 R similar to AfsQ1; two-component system response regulator complement(5733354..5734061) Streptomyces avermitilis MA-4680 1215472 NP_825882.1 CDS SAV_4705 NC_003155.4 5734105 5734695 R hypothetical protein complement(5734105..5734695) Streptomyces avermitilis MA-4680 1215473 NP_825883.1 CDS sig41 NC_003155.4 5734746 5735285 R ECF subfamily RNA polymerase sigma factor complement(5734746..5735285) Streptomyces avermitilis MA-4680 1211049 NP_825884.1 CDS mutY NC_003155.4 5735621 5736562 R G/C -> T/A transversion; adenine glycosylase complement(5735621..5736562) Streptomyces avermitilis MA-4680 1211050 NP_825885.1 CDS SAV_4708 NC_003155.4 5737512 5737886 D hypothetical protein 5737512..5737886 Streptomyces avermitilis MA-4680 1215474 NP_825886.1 CDS SAV_4709 NC_003155.4 5738160 5739284 R non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA complement(5738160..5739284) Streptomyces avermitilis MA-4680 1215475 NP_825887.1 CDS radA NC_003155.4 5739366 5740775 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(5739366..5740775) Streptomyces avermitilis MA-4680 1211051 NP_825888.1 CDS SAV_4711 NC_003155.4 5741117 5742865 D alanine-rich protein 5741117..5742865 Streptomyces avermitilis MA-4680 1215476 NP_825889.1 CDS SAV_4712 NC_003155.4 5742892 5743761 R hypothetical protein complement(5742892..5743761) Streptomyces avermitilis MA-4680 1215477 NP_825890.1 CDS ppx2 NC_003155.4 5743833 5744765 D PF02541: Ppx/GppA phosphatase family; exopolyphosphatase 5743833..5744765 Streptomyces avermitilis MA-4680 1215478 NP_825891.1 CDS SAV_4714 NC_003155.4 5745258 5746067 D PF01261: AP endonuclease family 2; hypothetical protein 5745258..5746067 Streptomyces avermitilis MA-4680 1215479 NP_825892.1 CDS SAV_4715 NC_003155.4 5746064 5746681 D TetR family transcriptional regulator 5746064..5746681 Streptomyces avermitilis MA-4680 1215480 NP_825893.1 CDS ilvD1 NC_003155.4 5746979 5748832 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 5746979..5748832 Streptomyces avermitilis MA-4680 1211052 NP_825894.1 CDS pkn16 NC_003155.4 5748959 5751157 R AfsK homolog; serine/threonine protein kinase complement(5748959..5751157) Streptomyces avermitilis MA-4680 1211053 NP_825895.1 CDS SAV_4718 NC_003155.4 5751260 5751604 D hypothetical protein 5751260..5751604 Streptomyces avermitilis MA-4680 1215481 NP_825896.1 CDS SAV_4719 NC_003155.4 5751675 5752259 D hypothetical protein 5751675..5752259 Streptomyces avermitilis MA-4680 1215482 NP_825897.1 CDS SAV_4720 NC_003155.4 5752401 5753033 D hypothetical protein 5752401..5753033 Streptomyces avermitilis MA-4680 1215483 NP_825898.1 CDS SAV_4721 NC_003155.4 5753085 5754560 R PF00916: Sulfate transporter family; sulfate transporter complement(5753085..5754560) Streptomyces avermitilis MA-4680 1215484 NP_825899.1 CDS SAV_4722 NC_003155.4 5754929 5755756 D ABC transporter ATP-binding protein 5754929..5755756 Streptomyces avermitilis MA-4680 1215485 NP_825900.1 CDS SAV_4723 NC_003155.4 5755753 5756544 D ABC transporter permease 5755753..5756544 Streptomyces avermitilis MA-4680 1215486 NP_825901.1 CDS proC NC_003155.4 5756668 5757477 D pyrroline-5-carboxylate reductase 5756668..5757477 Streptomyces avermitilis MA-4680 1211054 NP_825902.1 CDS trpS2 NC_003155.4 5757496 5758491 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(5757496..5758491) Streptomyces avermitilis MA-4680 1211055 NP_825903.1 CDS SAV_4726 NC_003155.4 5764588 5765232 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 5764588..5765232 Streptomyces avermitilis MA-4680 1215487 NP_825904.1 CDS SAV_4727 NC_003155.4 5765381 5766082 D hypothetical protein 5765381..5766082 Streptomyces avermitilis MA-4680 1215488 NP_825905.1 CDS SAV_4728 NC_003155.4 5766176 5767387 D PF07690: Major Facilitator Superfamily; integral membrane transport protein 5766176..5767387 Streptomyces avermitilis MA-4680 1215489 NP_825906.1 CDS acuC NC_003155.4 5767407 5768510 D acetoin dehydrogenase 5767407..5768510 Streptomyces avermitilis MA-4680 1211059 NP_825907.1 CDS SAV_4730 NC_003155.4 5768693 5769508 D hypothetical protein 5768693..5769508 Streptomyces avermitilis MA-4680 1215490 NP_825908.1 CDS SAV_4731 NC_003155.4 5769605 5769850 D hypothetical protein 5769605..5769850 Streptomyces avermitilis MA-4680 1215491 NP_825909.1 CDS SAV_4732 NC_003155.4 5770447 5771496 D NAD-dependent epimerase/dehydratase 5770447..5771496 Streptomyces avermitilis MA-4680 1215492 NP_825910.1 CDS SAV_4733 NC_003155.4 5771511 5772557 D acyltransferase 5771511..5772557 Streptomyces avermitilis MA-4680 1215493 NP_825911.1 CDS SAV_4734 NC_003155.4 5772617 5773852 R hypothetical protein complement(5772617..5773852) Streptomyces avermitilis MA-4680 1215494 NP_825912.1 CDS sig42 NC_003155.4 5774150 5774926 R ECF subfamily RNA polymerase sigma factor complement(5774150..5774926) Streptomyces avermitilis MA-4680 1211060 NP_825913.1 CDS serB1 NC_003155.4 5775345 5776235 R 3-phosphoserine phosphatase complement(5775345..5776235) Streptomyces avermitilis MA-4680 1211061 NP_825914.1 CDS SAV_4737 NC_003155.4 5776429 5776737 D redoxin 5776429..5776737 Streptomyces avermitilis MA-4680 1215495 NP_825915.1 CDS SAV_4738 NC_003155.4 5777053 5777811 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 5777053..5777811 Streptomyces avermitilis MA-4680 1215496 NP_825916.1 CDS hemA NC_003155.4 5777808 5779517 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 5777808..5779517 Streptomyces avermitilis MA-4680 1211062 NP_825917.1 CDS hemC NC_003155.4 5779514 5780488 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 5779514..5780488 Streptomyces avermitilis MA-4680 1211063 NP_825918.1 CDS hemD NC_003155.4 5780485 5782200 D uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase 5780485..5782200 Streptomyces avermitilis MA-4680 1211064 NP_825919.1 CDS hemB NC_003155.4 5782340 5783332 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 5782340..5783332 Streptomyces avermitilis MA-4680 1211065 NP_825920.1 CDS SAV_4743 NC_003155.4 5783378 5784094 R hypothetical protein complement(5783378..5784094) Streptomyces avermitilis MA-4680 1215497 NP_825921.1 CDS SAV_4744 NC_003155.4 5784150 5785505 D DNA-binding protein 5784150..5785505 Streptomyces avermitilis MA-4680 1215498 NP_825922.1 CDS SAV_4745 NC_003155.4 5785614 5786516 D PF04672: Protein of unknown function (DUF574); hypothetical protein 5785614..5786516 Streptomyces avermitilis MA-4680 1215499 NP_825923.1 CDS SAV_4746 NC_003155.4 5786563 5787516 R phosphotransferase complement(5786563..5787516) Streptomyces avermitilis MA-4680 1215500 NP_825924.1 CDS SAV_4747 NC_003155.4 5787654 5788565 R hypothetical protein complement(5787654..5788565) Streptomyces avermitilis MA-4680 1215501 NP_825925.1 CDS argS NC_003155.4 5788728 5790500 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(5788728..5790500) Streptomyces avermitilis MA-4680 1211066 NP_825926.1 CDS lysK NC_003155.4 5790745 5792391 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 5790745..5792391 Streptomyces avermitilis MA-4680 1211067 NP_825927.1 CDS SAV_4750 NC_003155.4 5792501 5793820 R hypothetical protein complement(5792501..5793820) Streptomyces avermitilis MA-4680 1215502 NP_825928.1 CDS SAV_4751 NC_003155.4 5793986 5794936 R hypothetical protein complement(5793986..5794936) Streptomyces avermitilis MA-4680 1215503 NP_825929.1 CDS SAV_4752 NC_003155.4 5795091 5795966 R hypothetical protein complement(5795091..5795966) Streptomyces avermitilis MA-4680 1215504 NP_825930.1 CDS SAV_4753 NC_003155.4 5796203 5797396 D PF01139: Uncharacterized protein family UPF0027; hypothetical protein 5796203..5797396 Streptomyces avermitilis MA-4680 1215505 NP_825931.1 CDS SAV_4754 NC_003155.4 5797440 5797877 R hypothetical protein complement(5797440..5797877) Streptomyces avermitilis MA-4680 1215506 NP_825932.1 CDS SAV_4755 NC_003155.4 5798544 5799323 R PF00106: short chain dehydrogenase; dehydrogenase complement(5798544..5799323) Streptomyces avermitilis MA-4680 1215507 NP_825933.1 CDS SAV_4756 NC_003155.4 5799434 5799772 R hypothetical protein complement(5799434..5799772) Streptomyces avermitilis MA-4680 1215508 NP_825934.1 CDS SAV_4757 NC_003155.4 5799890 5800381 D MarR family transcriptional regulator 5799890..5800381 Streptomyces avermitilis MA-4680 1215509 NP_825935.1 CDS SAV_4758 NC_003155.4 5800409 5800819 R PF01638: Transcriptional regulator; transcriptional regulator complement(5800409..5800819) Streptomyces avermitilis MA-4680 1215510 NP_825936.1 CDS SAV_4759 NC_003155.4 5800956 5801834 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 5800956..5801834 Streptomyces avermitilis MA-4680 1215511 NP_825937.1 CDS SAV_4760 NC_003155.4 5801897 5803312 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(5801897..5803312) Streptomyces avermitilis MA-4680 1215512 NP_825938.1 CDS SAV_4761 NC_003155.4 5803321 5803845 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 5803321..5803845 Streptomyces avermitilis MA-4680 1215513 NP_825939.1 CDS SAV_4762 NC_003155.4 5803942 5804751 R AraC family transcription regulator complement(5803942..5804751) Streptomyces avermitilis MA-4680 1215514 NP_825940.1 CDS SAV_4763 NC_003155.4 5804947 5806041 D PF00296: Luciferase-like monooxygenase; monooxygenase 5804947..5806041 Streptomyces avermitilis MA-4680 1215515 NP_825941.1 CDS SAV_4764 NC_003155.4 5806041 5806769 D NAD(P)H-dependent FMN reductase 5806041..5806769 Streptomyces avermitilis MA-4680 1215516 NP_825942.1 CDS SAV_4765 NC_003155.4 5806803 5808941 R PF03929: PepSY-associated TM helix; hypothetical protein complement(5806803..5808941) Streptomyces avermitilis MA-4680 1215517 NP_825943.1 CDS SAV_4766 NC_003155.4 5808938 5810263 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(5808938..5810263) Streptomyces avermitilis MA-4680 1215518 NP_825944.1 CDS SAV_4767 NC_003155.4 5810406 5811143 D two-component system response regulator 5810406..5811143 Streptomyces avermitilis MA-4680 1215519 NP_825945.1 CDS SAV_4768 NC_003155.4 5811144 5812799 D two-component system sensor kinase 5811144..5812799 Streptomyces avermitilis MA-4680 1215520 NP_825946.1 CDS SAV_4769 NC_003155.4 5812840 5814837 R PF03023: MviN-like protein; amino acid transporter complement(5812840..5814837) Streptomyces avermitilis MA-4680 1215521 NP_825947.1 CDS SAV_4770 NC_003155.4 5815106 5815591 D hypothetical protein 5815106..5815591 Streptomyces avermitilis MA-4680 1215522 NP_825948.1 CDS SAV_4771 NC_003155.4 5815897 5816517 D hypothetical protein 5815897..5816517 Streptomyces avermitilis MA-4680 1215523 NP_825949.1 CDS SAV_4772 NC_003155.4 5816453 5817148 R DJ-1/PfpI family transcriptional regulator complement(5816453..5817148) Streptomyces avermitilis MA-4680 1215524 NP_825950.1 CDS abaB2 NC_003155.4 5817276 5818232 D LysR family transcriptional regulator 5817276..5818232 Streptomyces avermitilis MA-4680 1215525 NP_825951.1 CDS SAV_4774 NC_003155.4 5818290 5820326 R amino acid permease complement(5818290..5820326) Streptomyces avermitilis MA-4680 1215526 NP_825952.1 CDS SAV_4775 NC_003155.4 5820572 5821132 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(5820572..5821132) Streptomyces avermitilis MA-4680 1215527 NP_825953.1 CDS cspD5 NC_003155.4 5821553 5821756 D cold shock protein 5821553..5821756 Streptomyces avermitilis MA-4680 1211068 NP_825954.1 CDS SAV_4777 NC_003155.4 5822204 5822881 R PF03713: Domain of unknown function (DUF305); hypothetical protein complement(5822204..5822881) Streptomyces avermitilis MA-4680 1215528 NP_825955.1 CDS SAV_4778 NC_003155.4 5822982 5823455 R hypothetical protein complement(5822982..5823455) Streptomyces avermitilis MA-4680 1215529 NP_825956.1 CDS SAV_4779 NC_003155.4 5823653 5824519 R catalyzes the cleavage of carbon-halogen bonds in aliphatic compounds forming a primary alcohol and a halide; haloalkane dehalogenase complement(5823653..5824519) Streptomyces avermitilis MA-4680 1215530 NP_825957.1 CDS SAV_4780 NC_003155.4 5824531 5824983 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(5824531..5824983) Streptomyces avermitilis MA-4680 1215531 NP_825958.1 CDS SAV_4781 NC_003155.4 5825037 5825858 R hypothetical protein complement(5825037..5825858) Streptomyces avermitilis MA-4680 1215532 NP_825959.1 CDS SAV_4782 NC_003155.4 5825957 5826550 D TetR family transcriptional regulator 5825957..5826550 Streptomyces avermitilis MA-4680 1215533 NP_825960.1 CDS SAV_4783 NC_003155.4 5826781 5827365 D regulatory protein 5826781..5827365 Streptomyces avermitilis MA-4680 1215534 NP_825961.1 CDS SAV_4784 NC_003155.4 5827528 5828130 D hypothetical protein 5827528..5828130 Streptomyces avermitilis MA-4680 1215535 NP_825962.1 CDS SAV_4785 NC_003155.4 5828137 5828376 D hypothetical protein 5828137..5828376 Streptomyces avermitilis MA-4680 1215536 NP_825963.1 CDS SAV_4786 NC_003155.4 5828339 5828806 D hypothetical protein 5828339..5828806 Streptomyces avermitilis MA-4680 1215537 NP_825964.1 CDS SAV_4787 NC_003155.4 5829173 5829550 D PF01740: STAS domain; anti-sigma factor antagonist 5829173..5829550 Streptomyces avermitilis MA-4680 1215538 NP_825965.1 CDS SAV_4788 NC_003155.4 5829547 5830257 D hypothetical protein 5829547..5830257 Streptomyces avermitilis MA-4680 1215539 NP_825966.1 CDS SAV_4789 NC_003155.4 5830360 5831214 R PF04672: Protein of unknown function (DUF574); hypothetical protein complement(5830360..5831214) Streptomyces avermitilis MA-4680 1215540 NP_825967.1 CDS SAV_4790 NC_003155.4 5831272 5832210 R LysR family transcriptional regulator complement(5831272..5832210) Streptomyces avermitilis MA-4680 1215541 NP_825968.1 CDS SAV_4791 NC_003155.4 5832251 5833252 D PF00892: Integral membrane protein DUF6; hypothetical protein 5832251..5833252 Streptomyces avermitilis MA-4680 1215542 NP_825969.1 CDS SAV_4792 NC_003155.4 5833276 5833944 D PF01118: Semialdehyde dehydrogenase, NAD binding domain; hypothetical protein 5833276..5833944 Streptomyces avermitilis MA-4680 1215543 NP_825970.1 CDS SAV_4793 NC_003155.4 5834013 5834450 R hypothetical protein complement(5834013..5834450) Streptomyces avermitilis MA-4680 1215544 NP_825971.1 CDS SAV_4794 NC_003155.4 5834609 5835223 D hypothetical protein 5834609..5835223 Streptomyces avermitilis MA-4680 1215545 NP_825972.1 CDS hemL NC_003155.4 5835211 5836527 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 5835211..5836527 Streptomyces avermitilis MA-4680 1211069 NP_825973.1 CDS SAV_4796 NC_003155.4 5836524 5837216 D phosphoglycerate mutase 5836524..5837216 Streptomyces avermitilis MA-4680 1215546 NP_825974.1 CDS SAV_4797 NC_003155.4 5837392 5838669 D PF01522: Polysaccharide deacetylase; hypothetical protein 5837392..5838669 Streptomyces avermitilis MA-4680 1215547 NP_825975.1 CDS SAV_4798 NC_003155.4 5838736 5839368 D PF00578: AhpC/TSA family; hypothetical protein 5838736..5839368 Streptomyces avermitilis MA-4680 1215548 NP_825976.1 CDS ccsA NC_003155.4 5839375 5840157 D cytochrome C biogenesis membrane protein 5839375..5840157 Streptomyces avermitilis MA-4680 1211070 NP_825977.1 CDS ccs-1 NC_003155.4 5840161 5841948 D cytochrome C biogenesis membrane protein 5840161..5841948 Streptomyces avermitilis MA-4680 1211071 NP_825978.1 CDS ccsB NC_003155.4 5841945 5843021 D cytochrome C assembly protein 5841945..5843021 Streptomyces avermitilis MA-4680 1211072 NP_825979.1 CDS SAV_4802 NC_003155.4 5843152 5843637 D hypothetical protein 5843152..5843637 Streptomyces avermitilis MA-4680 1215549 NP_825980.1 CDS SAV_4803 NC_003155.4 5843661 5845208 R PF01094: Receptor family ligand binding region; hypothetical protein complement(5843661..5845208) Streptomyces avermitilis MA-4680 1215550 NP_825981.1 CDS SAV_4804 NC_003155.4 5845208 5847307 R hypothetical protein complement(5845208..5847307) Streptomyces avermitilis MA-4680 1215551 NP_825982.1 CDS SAV_4805 NC_003155.4 5847436 5848410 R PF03171: 2OG-Fe(II) oxygenase superfamily; oxidoreductase complement(5847436..5848410) Streptomyces avermitilis MA-4680 1215552 NP_825983.1 CDS cdd4 NC_003155.4 5848403 5848864 R PF00383: Cytidine and deoxycytidylate deaminase zinc-binding region; cytidine/deoxycytidine deaminase complement(5848403..5848864) Streptomyces avermitilis MA-4680 1211073 NP_825984.1 CDS SAV_4807 NC_003155.4 5849102 5849545 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(5849102..5849545) Streptomyces avermitilis MA-4680 1215553 NP_825985.1 CDS SAV_4808 NC_003155.4 5849693 5850085 R hypothetical protein complement(5849693..5850085) Streptomyces avermitilis MA-4680 1215554 NP_825986.1 CDS ubiX NC_003155.4 5850173 5851624 D PF01977: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; decarboxylase 5850173..5851624 Streptomyces avermitilis MA-4680 1211074 NP_825987.1 CDS ubiA NC_003155.4 5851621 5852526 D UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 5851621..5852526 Streptomyces avermitilis MA-4680 1211075 NP_825988.1 CDS ubiD NC_003155.4 5852782 5853447 D PF02441: Flavoprotein; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 5852782..5853447 Streptomyces avermitilis MA-4680 1211076 NP_825989.1 CDS SAV_4812 NC_003155.4 5853523 5853978 D transcription regulator AsnC 5853523..5853978 Streptomyces avermitilis MA-4680 1215555 NP_825990.1 CDS SAV_4813 NC_003155.4 5854065 5855228 D PF04055: Radical SAM superfamily; hypothetical protein 5854065..5855228 Streptomyces avermitilis MA-4680 1215556 NP_825991.1 CDS SAV_4814 NC_003155.4 5855236 5855772 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 5855236..5855772 Streptomyces avermitilis MA-4680 1215557 NP_825992.1 CDS SAV_4815 NC_003155.4 5855867 5856166 D hypothetical protein 5855867..5856166 Streptomyces avermitilis MA-4680 1215558 NP_825993.1 CDS SAV_4816 NC_003155.4 5856259 5856900 D TetR family transcriptional regulator 5856259..5856900 Streptomyces avermitilis MA-4680 1215559 NP_825994.1 CDS SAV_4817 NC_003155.4 5856928 5857854 R PF01575: MaoC like domain; dehydratase complement(5856928..5857854) Streptomyces avermitilis MA-4680 1215560 NP_825995.1 CDS fadD10 NC_003155.4 5858175 5860091 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase 5858175..5860091 Streptomyces avermitilis MA-4680 1211077 NP_825996.1 CDS SAV_4819 NC_003155.4 5860168 5860665 D hypothetical protein 5860168..5860665 Streptomyces avermitilis MA-4680 1215561 NP_825997.1 CDS cspD6 NC_003155.4 5860779 5860982 R cold shock protein complement(5860779..5860982) Streptomyces avermitilis MA-4680 1211078 NP_825998.1 CDS SAV_4821 NC_003155.4 5861326 5862174 D PF02621: Uncharacterized ACR, COG1427; hypothetical protein 5861326..5862174 Streptomyces avermitilis MA-4680 1215562 NP_825999.1 CDS pkn17 NC_003155.4 5862253 5864004 D serine/threonine protein kinase 5862253..5864004 Streptomyces avermitilis MA-4680 1211079 NP_826000.1 CDS SAV_4823 NC_003155.4 5863997 5864677 R hypothetical protein complement(5863997..5864677) Streptomyces avermitilis MA-4680 1215563 NP_826001.1 CDS SAV_4824 NC_003155.4 5864704 5865447 D PF01478: Type IV leader peptidase family; type IV peptidase 5864704..5865447 Streptomyces avermitilis MA-4680 1215564 NP_826002.1 CDS SAV_4825 NC_003155.4 5865567 5866766 D PF04055: radical SAM superfamily domain; hypothetical protein 5865567..5866766 Streptomyces avermitilis MA-4680 1215565 NP_826003.1 CDS SAV_4826 NC_003155.4 5866774 5867223 D hypothetical protein 5866774..5867223 Streptomyces avermitilis MA-4680 1215566 NP_826004.1 CDS SAV_4827 NC_003155.4 5867255 5868304 R PF00704: Glycosyl hydrolases family 18; sugar hydrolase complement(5867255..5868304) Streptomyces avermitilis MA-4680 1215567 NP_826005.1 CDS SAV_4828 NC_003155.4 5868612 5869004 D hypothetical protein 5868612..5869004 Streptomyces avermitilis MA-4680 1215568 NP_826006.1 CDS SAV_4829 NC_003155.4 5869025 5871397 D PF01522: Polysaccharide deacetylase; polysaccharide deacetylase/glycosyl transferase 5869025..5871397 Streptomyces avermitilis MA-4680 1215569 NP_826007.1 CDS SAV_4830 NC_003155.4 5871397 5872812 D PF01757: Acyltransferase family; hypothetical protein 5871397..5872812 Streptomyces avermitilis MA-4680 1215570 NP_826008.1 CDS ubiE NC_003155.4 5872885 5873580 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 5872885..5873580 Streptomyces avermitilis MA-4680 1211080 NP_826009.1 CDS SAV_4832 NC_003155.4 5873712 5876213 D PF03884: Domain of unknown function (DUF329); hypothetical protein 5873712..5876213 Streptomyces avermitilis MA-4680 1215571 NP_826010.1 CDS SAV_4833 NC_003155.4 5876206 5876553 R PF03793: PASTA domain; hypothetical protein complement(5876206..5876553) Streptomyces avermitilis MA-4680 1215572 NP_826011.1 CDS SAV_4834 NC_003155.4 5876638 5877144 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(5876638..5877144) Streptomyces avermitilis MA-4680 1215573 NP_826012.1 CDS SAV_4835 NC_003155.4 5877245 5878549 D PF01494: FAD binding domain; electron transfer oxidoreductase 5877245..5878549 Streptomyces avermitilis MA-4680 1215574 NP_826013.1 CDS SAV_4836 NC_003155.4 5878799 5879617 R Seems to have no N-terminal signal sequence; NLP/P60-family protein complement(5878799..5879617) Streptomyces avermitilis MA-4680 1215575 NP_826014.1 CDS nuoA1 NC_003155.4 5880403 5880762 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 5880403..5880762 Streptomyces avermitilis MA-4680 1211081 NP_826015.1 CDS nuoB1 NC_003155.4 5880778 5881332 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 5880778..5881332 Streptomyces avermitilis MA-4680 1211082 NP_826016.1 CDS nuoC NC_003155.4 5881329 5882075 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 5881329..5882075 Streptomyces avermitilis MA-4680 1211083 NP_826017.1 CDS nuoD1 NC_003155.4 5882072 5883403 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 5882072..5883403 Streptomyces avermitilis MA-4680 1211084 NP_826018.1 CDS nuoE NC_003155.4 5883400 5884263 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 5883400..5884263 Streptomyces avermitilis MA-4680 1211085 NP_826019.1 CDS nuoF1 NC_003155.4 5884260 5885609 D NADH dehydrogenase I chain F 5884260..5885609 Streptomyces avermitilis MA-4680 1211086 NP_826020.1 CDS nuoG1 NC_003155.4 5885606 5888110 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 5885606..5888110 Streptomyces avermitilis MA-4680 1211087 NP_826021.1 CDS nuoH1 NC_003155.4 5888107 5889471 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 5888107..5889471 Streptomyces avermitilis MA-4680 1211088 NP_826022.1 CDS nuoI1 NC_003155.4 5889464 5890066 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 5889464..5890066 Streptomyces avermitilis MA-4680 1211089 NP_826023.1 CDS nuoJ1 NC_003155.4 5890063 5890905 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 5890063..5890905 Streptomyces avermitilis MA-4680 1211090 NP_826024.1 CDS nuoK1 NC_003155.4 5890902 5891201 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 5890902..5891201 Streptomyces avermitilis MA-4680 1211091 NP_826025.1 CDS nuoL1 NC_003155.4 5891215 5893119 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 5891215..5893119 Streptomyces avermitilis MA-4680 1211092 NP_826026.1 CDS nuoM1 NC_003155.4 5893125 5894723 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 5893125..5894723 Streptomyces avermitilis MA-4680 1211093 NP_826027.1 CDS nuoN1 NC_003155.4 5894720 5896348 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 5894720..5896348 Streptomyces avermitilis MA-4680 1211094 NP_826028.1 CDS recQ NC_003155.4 5896755 5898731 D PF00270: DEAD/DEAH box helicase; ATP-dependent DNA helicase 5896755..5898731 Streptomyces avermitilis MA-4680 1211095 NP_826029.1 CDS SAV_4852 NC_003155.4 5898810 5901629 R PF00890: FAD binding domain; putative oxidoreductase/HEAT repeat-containing protein complement(5898810..5901629) Streptomyces avermitilis MA-4680 1215576 NP_826030.1 CDS SAV_4853 NC_003155.4 5901695 5902507 R ABC transporter ATP-binding protein complement(5901695..5902507) Streptomyces avermitilis MA-4680 1215577 NP_826031.1 CDS SAV_4854 NC_003155.4 5902488 5903357 R ABC transporter permease complement(5902488..5903357) Streptomyces avermitilis MA-4680 1215578 NP_826032.1 CDS SAV_4855 NC_003155.4 5903354 5904700 R ABC transporter substrate-binding protein complement(5903354..5904700) Streptomyces avermitilis MA-4680 1215579 NP_826033.1 CDS fdxE NC_003155.4 5904716 5904943 R ferredoxin complement(5904716..5904943) Streptomyces avermitilis MA-4680 1211096 NP_826034.1 CDS SAV_4857 NC_003155.4 5905018 5905797 R PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator complement(5905018..5905797) Streptomyces avermitilis MA-4680 1215580 NP_826035.1 CDS fahA NC_003155.4 5906169 5907392 R fumarylacetoacetase complement(5906169..5907392) Streptomyces avermitilis MA-4680 1211097 NP_826036.1 CDS SAV_4859 NC_003155.4 5907567 5908856 D hypothetical protein 5907567..5908856 Streptomyces avermitilis MA-4680 1215581 NP_826037.1 CDS SAV_4860 NC_003155.4 5908906 5910108 D PF00070: Pyridine nucleotide-disulphide oxidoreductase; oxidoreductase 5908906..5910108 Streptomyces avermitilis MA-4680 1215582 NP_826038.1 CDS SAV_4861 NC_003155.4 5910408 5911220 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 5910408..5911220 Streptomyces avermitilis MA-4680 1215583 NP_826039.1 CDS SAV_4862 NC_003155.4 5911238 5911714 R PF01464: Transglycosylase SLT domain; hypothetical protein complement(5911238..5911714) Streptomyces avermitilis MA-4680 1215584 NP_826040.1 CDS SAV_4863 NC_003155.4 5912224 5914278 R PF02129: Pro dipeptidyl-peptidase (S15 family); hypothetical protein complement(5912224..5914278) Streptomyces avermitilis MA-4680 1215585 NP_826041.1 CDS grcC NC_003155.4 5914570 5915580 D probably geranylgeranyl pyrophosphate synthase; polyprenyl diphosphate synthase 5914570..5915580 Streptomyces avermitilis MA-4680 1211098 NP_826042.1 CDS SAV_4865 NC_003155.4 5915733 5916761 D hypothetical protein 5915733..5916761 Streptomyces avermitilis MA-4680 1215586 NP_826043.1 CDS SAV_4866 NC_003155.4 5917037 5918266 D PF03548: Outer membrane lipoprotein carrier protein LolA; hypothetical protein 5917037..5918266 Streptomyces avermitilis MA-4680 1215587 NP_826044.1 CDS SAV_4867 NC_003155.4 5918301 5919341 D ABC transporter ATP-binding protein 5918301..5919341 Streptomyces avermitilis MA-4680 1215588 NP_826045.1 CDS SAV_4868 NC_003155.4 5919328 5920221 D ABC transporter permease 5919328..5920221 Streptomyces avermitilis MA-4680 1215589 NP_826046.1 CDS SAV_4869 NC_003155.4 5920258 5920842 R PF02525: Flavodoxin-like fold; hypothetical protein complement(5920258..5920842) Streptomyces avermitilis MA-4680 1215590 NP_826047.1 CDS SAV_4870 NC_003155.4 5921048 5921746 R hypothetical protein complement(5921048..5921746) Streptomyces avermitilis MA-4680 1215591 NP_826048.1 CDS SAV_4871 NC_003155.4 5921949 5923703 D hypothetical protein 5921949..5923703 Streptomyces avermitilis MA-4680 1215592 NP_826049.1 CDS SAV_4872 NC_003155.4 5923841 5924788 R PF04389: Peptidase family M28; aminopeptidase complement(5923841..5924788) Streptomyces avermitilis MA-4680 1215593 NP_826050.1 CDS SAV_4873 NC_003155.4 5924915 5925895 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(5924915..5925895) Streptomyces avermitilis MA-4680 1215594 NP_826051.1 CDS SAV_4874 NC_003155.4 5926028 5926882 R PF01113: Dihydrodipicolinate reductase, N-terminus; hypothetical protein complement(5926028..5926882) Streptomyces avermitilis MA-4680 1215595 NP_826052.1 CDS SAV_4875 NC_003155.4 5926972 5927445 D PF01638: Transcriptional regulator; transcriptional regulator 5926972..5927445 Streptomyces avermitilis MA-4680 1215596 NP_826053.1 CDS korB NC_003155.4 5927459 5928538 R catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta complement(5927459..5928538) Streptomyces avermitilis MA-4680 1215597 NP_826054.1 CDS korA NC_003155.4 5928531 5930459 R PF01855: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit complement(5928531..5930459) Streptomyces avermitilis MA-4680 1215598 NP_826055.1 CDS SAV_4878 NC_003155.4 5930746 5931417 R two-component system response regulator complement(5930746..5931417) Streptomyces avermitilis MA-4680 1215599 NP_826056.1 CDS SAV_4879 NC_003155.4 5931931 5933289 R two-component system sensor kinase complement(5931931..5933289) Streptomyces avermitilis MA-4680 1215600 NP_826057.1 CDS SAV_4880 NC_003155.4 5933658 5934899 R two-component system sensor kinase complement(5933658..5934899) Streptomyces avermitilis MA-4680 1215601 NP_826058.1 CDS nuoA2 NC_003155.4 5935153 5935593 D similar to many chloroplastic ubiquinone dehydrogenase; NADH dehydrogenase I chain A 5935153..5935593 Streptomyces avermitilis MA-4680 1211099 NP_826059.1 CDS nuoB2 NC_003155.4 5935584 5936195 D similar to many eukaryotic ubiquinone dehydrogenase; NADH dehydrogenase I chain B 5935584..5936195 Streptomyces avermitilis MA-4680 1211100 NP_826060.1 CDS SAV_4883 NC_003155.4 5936192 5937706 D PF00329: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; NADH dehydrogenase 5936192..5937706 Streptomyces avermitilis MA-4680 1215602 NP_826061.1 CDS nuoH2 NC_003155.4 5937703 5938671 D NADH dehydrogenase I chain H 5937703..5938671 Streptomyces avermitilis MA-4680 1211101 NP_826062.1 CDS nuoI2 NC_003155.4 5938674 5939324 D NADH dehydrogenase I chain I 5938674..5939324 Streptomyces avermitilis MA-4680 1211102 NP_826063.1 CDS nuoJ2 NC_003155.4 5939321 5939944 D NADH dehydrogenase I chain J 5939321..5939944 Streptomyces avermitilis MA-4680 1211103 NP_826064.1 CDS nuoK2 NC_003155.4 5939944 5940333 D NADH dehydrogenase I chain K 5939944..5940333 Streptomyces avermitilis MA-4680 1211104 NP_826065.1 CDS nuoL2 NC_003155.4 5940330 5942321 D NADH dehydrogenase I chain L 5940330..5942321 Streptomyces avermitilis MA-4680 1211105 NP_826066.1 CDS nuoM2 NC_003155.4 5942328 5943911 D PF05921: Actinomycete protein of unknown function (DUF875); NADH dehydrogenase I chain M 5942328..5943911 Streptomyces avermitilis MA-4680 1211106 NP_826067.1 CDS nuoN2 NC_003155.4 5943908 5945407 D NADH dehydrogenase I chain N 5943908..5945407 Streptomyces avermitilis MA-4680 1211107 NP_826068.1 CDS htpX1 NC_003155.4 5945620 5946483 D putative metalloprotease; heat shock protein HtpX 5945620..5946483 Streptomyces avermitilis MA-4680 1215603 NP_826069.1 CDS SAV_4892 NC_003155.4 5946480 5946872 D PF03733: Domain of unknown function (DUF307); hypothetical protein 5946480..5946872 Streptomyces avermitilis MA-4680 1215604 NP_826070.1 CDS SAV_4893 NC_003155.4 5946999 5947565 D hypothetical protein 5946999..5947565 Streptomyces avermitilis MA-4680 1215605 NP_826071.1 CDS SAV_4894 NC_003155.4 5947634 5948902 R amino acid transporter complement(5947634..5948902) Streptomyces avermitilis MA-4680 1215606 NP_826072.1 CDS SAV_4895 NC_003155.4 5949050 5949316 D PF04226: Transglycosylase associated protein; hypothetical protein 5949050..5949316 Streptomyces avermitilis MA-4680 1215607 NP_826073.1 CDS SAV_4896 NC_003155.4 5949458 5949946 R putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein complement(5949458..5949946) Streptomyces avermitilis MA-4680 1215608 NP_826074.1 CDS amiB NC_003155.4 5952467 5953648 R PF01546: Peptidase family M20/M25/M40; amidohydrolase complement(5952467..5953648) Streptomyces avermitilis MA-4680 1215609 NP_826075.1 CDS SAV_4898 NC_003155.4 5954090 5954746 R PF00106: short chain dehydrogenase; hypothetical protein complement(5954090..5954746) Streptomyces avermitilis MA-4680 1215610 NP_826076.1 CDS SAV_4899 NC_003155.4 5954988 5956229 R PF01979: Amidohydrolase family; hydrolase complement(5954988..5956229) Streptomyces avermitilis MA-4680 1215611 NP_826077.1 CDS rpmG NC_003155.4 5956882 5957046 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 5956882..5957046 Streptomyces avermitilis MA-4680 1211111 NP_826078.1 CDS SAV_4901 NC_003155.4 5957202 5957654 D PF05921: Actinomycete protein of unknown function (DUF875); hypothetical protein 5957202..5957654 Streptomyces avermitilis MA-4680 1215612 NP_826079.1 CDS SAV_4902 NC_003155.4 5957657 5958085 D PF01575: MaoC like domain; hypothetical protein 5957657..5958085 Streptomyces avermitilis MA-4680 1215613 NP_826080.1 CDS SAV_4903 NC_003155.4 5958310 5958879 D TetR family transcriptional regulator 5958310..5958879 Streptomyces avermitilis MA-4680 1215614 NP_826081.1 CDS SAV_4904 NC_003155.4 5958993 5960462 D drug resistance, PF07690: Major Facilitator Superfamily; transmembrane efflux protein 5958993..5960462 Streptomyces avermitilis MA-4680 1215615 NP_826082.1 CDS murB NC_003155.4 5960568 5961662 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 5960568..5961662 Streptomyces avermitilis MA-4680 1211112 NP_826083.1 CDS add4 NC_003155.4 5961860 5962888 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(5961860..5962888) Streptomyces avermitilis MA-4680 1211113 NP_826084.1 CDS aspC1 NC_003155.4 5963056 5964282 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(5963056..5964282) Streptomyces avermitilis MA-4680 1211114 NP_826085.1 CDS secE NC_003155.4 5964712 5964999 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 5964712..5964999 Streptomyces avermitilis MA-4680 1211116 NP_826086.1 CDS nusG NC_003155.4 5965077 5965940 D transcription antitermination protein 5965077..5965940 Streptomyces avermitilis MA-4680 1211117 NP_826087.1 CDS rplK NC_003155.4 5966111 5966545 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 5966111..5966545 Streptomyces avermitilis MA-4680 1211118 NP_826088.1 CDS rplA NC_003155.4 5966625 5967350 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 5966625..5967350 Streptomyces avermitilis MA-4680 1211119 NP_826089.1 CDS rplJ NC_003155.4 5967982 5968512 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 5967982..5968512 Streptomyces avermitilis MA-4680 1211120 NP_826090.1 CDS rplL NC_003155.4 5968622 5969005 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 5968622..5969005 Streptomyces avermitilis MA-4680 1211121 NP_826091.1 CDS rpoB NC_003155.4 5969568 5973113 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 5969568..5973113 Streptomyces avermitilis MA-4680 1211122 NP_826092.1 CDS rpoC NC_003155.4 5973224 5977123 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 5973224..5977123 Streptomyces avermitilis MA-4680 1211123 NP_826093.1 CDS SAV_4916 NC_003155.4 5977160 5977861 D hypothetical protein 5977160..5977861 Streptomyces avermitilis MA-4680 1215616 NP_826094.1 CDS rpsL NC_003155.4 5978149 5978520 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 5978149..5978520 Streptomyces avermitilis MA-4680 1211124 NP_826095.1 CDS rpsG NC_003155.4 5978523 5978993 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 5978523..5978993 Streptomyces avermitilis MA-4680 1211125 NP_826096.1 CDS fusA1 NC_003155.4 5979033 5981162 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 5979033..5981162 Streptomyces avermitilis MA-4680 1211126 NP_826097.1 CDS tuf NC_003155.4 5981306 5982499 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 5981306..5982499 Streptomyces avermitilis MA-4680 1211127 NP_826098.1 CDS SAV_4921 NC_003155.4 5982592 5982705 D hypothetical protein 5982592..5982705 Streptomyces avermitilis MA-4680 1215617 NP_826099.1 CDS SAV_4922 NC_003155.4 5982754 5983359 R PF06821: Protein of unknown function (DUF1234); hypothetical protein complement(5982754..5983359) Streptomyces avermitilis MA-4680 1215618 NP_826100.1 CDS SAV_4923 NC_003155.4 5983411 5984361 D LysR family transcriptional regulator 5983411..5984361 Streptomyces avermitilis MA-4680 1215619 NP_826101.1 CDS SAV_4924 NC_003155.4 5984370 5986484 R PF02585: Uncharacterised LmbE-like protein, COG2120; hypothetical protein complement(5984370..5986484) Streptomyces avermitilis MA-4680 1215620 NP_826102.1 CDS rpsJ NC_003155.4 5987138 5987446 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 5987138..5987446 Streptomyces avermitilis MA-4680 1211128 NP_826103.1 CDS rplC NC_003155.4 5987464 5988108 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 5987464..5988108 Streptomyces avermitilis MA-4680 1211129 NP_826104.1 CDS rplD NC_003155.4 5988114 5988779 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 5988114..5988779 Streptomyces avermitilis MA-4680 1211130 NP_826105.1 CDS rplW NC_003155.4 5988779 5989195 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 5988779..5989195 Streptomyces avermitilis MA-4680 1211131 NP_826106.1 CDS rplB NC_003155.4 5989235 5990071 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 5989235..5990071 Streptomyces avermitilis MA-4680 1211132 NP_826107.1 CDS rpsS NC_003155.4 5990084 5990365 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 5990084..5990365 Streptomyces avermitilis MA-4680 1211133 NP_826108.1 CDS rplV NC_003155.4 5990408 5990755 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 5990408..5990755 Streptomyces avermitilis MA-4680 1211134 NP_826109.1 CDS rpsC NC_003155.4 5990755 5991582 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 5990755..5991582 Streptomyces avermitilis MA-4680 1211135 NP_826110.1 CDS rplP NC_003155.4 5991589 5992008 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 5991589..5992008 Streptomyces avermitilis MA-4680 1211136 NP_826111.1 CDS rpmC NC_003155.4 5992008 5992232 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 5992008..5992232 Streptomyces avermitilis MA-4680 1211137 NP_826112.1 CDS rpsQ NC_003155.4 5992232 5992516 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 5992232..5992516 Streptomyces avermitilis MA-4680 1211138 NP_826113.1 CDS rplN NC_003155.4 5992620 5992988 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 5992620..5992988 Streptomyces avermitilis MA-4680 1211139 NP_826114.1 CDS rplX NC_003155.4 5992991 5993314 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 5992991..5993314 Streptomyces avermitilis MA-4680 1211140 NP_826115.1 CDS rplE NC_003155.4 5993314 5993871 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 5993314..5993871 Streptomyces avermitilis MA-4680 1211141 NP_826116.1 CDS rpsN NC_003155.4 5993877 5994062 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 5993877..5994062 Streptomyces avermitilis MA-4680 1211142 NP_826117.1 CDS rpsH NC_003155.4 5994274 5994672 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 5994274..5994672 Streptomyces avermitilis MA-4680 1211143 NP_826118.1 CDS rplF NC_003155.4 5994697 5995236 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 5994697..5995236 Streptomyces avermitilis MA-4680 1211144 NP_826119.1 CDS rplR NC_003155.4 5995240 5995623 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 5995240..5995623 Streptomyces avermitilis MA-4680 1211145 NP_826120.1 CDS rpsE NC_003155.4 5995665 5996270 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 5995665..5996270 Streptomyces avermitilis MA-4680 1211146 NP_826121.1 CDS rpmD NC_003155.4 5996273 5996455 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 5996273..5996455 Streptomyces avermitilis MA-4680 1211147 NP_826122.1 CDS rplO NC_003155.4 5996458 5996913 D late assembly protein; 50S ribosomal protein L15 5996458..5996913 Streptomyces avermitilis MA-4680 1211148 NP_826123.1 CDS secY NC_003155.4 5997158 5998474 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 5997158..5998474 Streptomyces avermitilis MA-4680 1211149 NP_826124.1 CDS adk NC_003155.4 5998474 5999136 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 5998474..5999136 Streptomyces avermitilis MA-4680 1211150 NP_826125.1 CDS map3 NC_003155.4 5999283 6000119 D PF00557: metallopeptidase family M24; methionine aminopeptidase 5999283..6000119 Streptomyces avermitilis MA-4680 1211151 NP_826126.1 CDS infA NC_003155.4 6000287 6000508 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 6000287..6000508 Streptomyces avermitilis MA-4680 1211152 NP_826127.1 CDS rpmJ NC_003155.4 6000568 6000681 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 6000568..6000681 Streptomyces avermitilis MA-4680 1211153 NP_826128.1 CDS rpsM NC_003155.4 6000885 6001265 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 6000885..6001265 Streptomyces avermitilis MA-4680 1211154 NP_826129.1 CDS rpsK NC_003155.4 6001363 6001767 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 6001363..6001767 Streptomyces avermitilis MA-4680 1211155 NP_826130.1 CDS rpoA NC_003155.4 6001910 6002932 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 6001910..6002932 Streptomyces avermitilis MA-4680 1211156 NP_826131.1 CDS rplQ NC_003155.4 6003114 6003617 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 6003114..6003617 Streptomyces avermitilis MA-4680 1211157 NP_826132.1 CDS truA NC_003155.4 6003707 6004564 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 6003707..6004564 Streptomyces avermitilis MA-4680 1211158 NP_826133.1 CDS SAV_4956 NC_003155.4 6004569 6005456 R hypothetical protein complement(6004569..6005456) Streptomyces avermitilis MA-4680 1215621 NP_826134.1 CDS rplM NC_003155.4 6005829 6006272 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 6005829..6006272 Streptomyces avermitilis MA-4680 1211159 NP_826135.1 CDS rpsI NC_003155.4 6006315 6006836 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 6006315..6006836 Streptomyces avermitilis MA-4680 1211160 NP_826136.1 CDS glmM NC_003155.4 6007048 6008406 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 6007048..6008406 Streptomyces avermitilis MA-4680 1211161 NP_826137.1 CDS SAV_4960 NC_003155.4 6008474 6009427 R PF04087: Domain of unknown function (DUF389); hypothetical protein complement(6008474..6009427) Streptomyces avermitilis MA-4680 1215622 NP_826138.1 CDS coaA NC_003155.4 6009444 6010433 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(6009444..6010433) Streptomyces avermitilis MA-4680 1211162 NP_826139.1 CDS SAV_4962 NC_003155.4 6010591 6010848 D hypothetical protein 6010591..6010848 Streptomyces avermitilis MA-4680 1215623 NP_826140.1 CDS glmS1 NC_003155.4 6011012 6012859 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 6011012..6012859 Streptomyces avermitilis MA-4680 1211163 NP_826141.1 CDS acpS NC_003155.4 6013029 6013400 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 6013029..6013400 Streptomyces avermitilis MA-4680 1211164 NP_826142.1 CDS SAV_4965 NC_003155.4 6013441 6014871 D PF03853: YjeF-related protein N-terminus; hypothetical protein 6013441..6014871 Streptomyces avermitilis MA-4680 1215624 NP_826143.1 CDS SAV_4966 NC_003155.4 6014923 6016140 D PF03734: ErfK/YbiS/YcfS/YnhG; hypothetical protein 6014923..6016140 Streptomyces avermitilis MA-4680 1215625 NP_826144.1 CDS alr NC_003155.4 6016209 6017384 D alanine racemase 6016209..6017384 Streptomyces avermitilis MA-4680 1211165 NP_826145.1 CDS SAV_4968 NC_003155.4 6017475 6018725 D PF00561: alpha/beta hydrolase fold; hydrolase 6017475..6018725 Streptomyces avermitilis MA-4680 1215626 NP_826146.1 CDS SAV_4969 NC_003155.4 6018685 6019212 D PF02367: Uncharacterised P-loop hydrolase UPF0079; hypothetical protein 6018685..6019212 Streptomyces avermitilis MA-4680 1215627 NP_826147.1 CDS SAV_4970 NC_003155.4 6019468 6019644 D hypothetical protein 6019468..6019644 Streptomyces avermitilis MA-4680 1215628 NP_826148.1 CDS SAV_4971 NC_003155.4 6019730 6020284 R hypothetical protein complement(6019730..6020284) Streptomyces avermitilis MA-4680 1215629 NP_826149.1 CDS SAV_4972 NC_003155.4 6020407 6021054 D PF00814: glycoprotease family; hypothetical protein 6020407..6021054 Streptomyces avermitilis MA-4680 1215630 NP_826150.1 CDS SAV_4973 NC_003155.4 6021072 6021554 D probably ribosomal-protein-alanine N-acetyltransferase; ribosomal-protein-alanine N-acetyltransferase 6021072..6021554 Streptomyces avermitilis MA-4680 1215631 NP_826151.1 CDS gcp NC_003155.4 6021547 6022671 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 6021547..6022671 Streptomyces avermitilis MA-4680 1211166 NP_826152.1 CDS SAV_4975 NC_003155.4 6022668 6022925 D hypothetical protein 6022668..6022925 Streptomyces avermitilis MA-4680 1215632 NP_826153.1 CDS SAV_4976 NC_003155.4 6023026 6023868 D DNA-binding protein 6023026..6023868 Streptomyces avermitilis MA-4680 1215633 NP_826154.1 CDS SAV_4977 NC_003155.4 6023865 6024116 D PF04149: Domain of unknown function (DUF397); hypothetical protein 6023865..6024116 Streptomyces avermitilis MA-4680 1215634 NP_826155.1 CDS SAV_4978 NC_003155.4 6024202 6025221 D LacI family transcriptional regulator 6024202..6025221 Streptomyces avermitilis MA-4680 1215635 NP_826156.1 CDS SAV_4979 NC_003155.4 6025409 6026713 D sugar ABC transporter substrate-binding protein 6025409..6026713 Streptomyces avermitilis MA-4680 1215636 NP_826157.1 CDS SAV_4980 NC_003155.4 6026723 6027775 D sugar ABC transporter permease 6026723..6027775 Streptomyces avermitilis MA-4680 1215637 NP_826158.1 CDS SAV_4981 NC_003155.4 6027772 6028668 D sugar ABC transporter permease 6027772..6028668 Streptomyces avermitilis MA-4680 1215638 NP_826159.1 CDS xynB2 NC_003155.4 6028705 6030933 D xylan 1,4-beta-xylosidase 6028705..6030933 Streptomyces avermitilis MA-4680 1211167 NP_826160.1 CDS SAV_4983 NC_003155.4 6031078 6032187 D LacI family transcriptional regulator 6031078..6032187 Streptomyces avermitilis MA-4680 1215639 NP_826161.1 CDS SAV_4984 NC_003155.4 6032380 6033735 D PF00331: Glycosyl hydrolase family 10; beta-1,4-xylanase 6032380..6033735 Streptomyces avermitilis MA-4680 1215640 NP_826162.1 CDS SAV_4985 NC_003155.4 6033808 6034893 D transcriptional regulator 6033808..6034893 Streptomyces avermitilis MA-4680 1215641 NP_826163.1 CDS SAV_4986 NC_003155.4 6035075 6035431 D PF04946: DGPF domain; hypothetical protein 6035075..6035431 Streptomyces avermitilis MA-4680 1215642 NP_826164.1 CDS sig43 NC_003155.4 6035525 6036799 D ECF subfamily RNA polymerase sigma factor 6035525..6036799 Streptomyces avermitilis MA-4680 1211168 NP_826165.1 CDS SAV_4988 NC_003155.4 6036912 6038084 R hypothetical protein complement(6036912..6038084) Streptomyces avermitilis MA-4680 1215643 NP_826166.1 CDS SAV_4989 NC_003155.4 6038220 6039095 D PF01522: Polysaccharide deacetylase; polysaccharide deacetylase 6038220..6039095 Streptomyces avermitilis MA-4680 1215644 NP_826167.1 CDS SAV_4990 NC_003155.4 6039092 6039922 D PF01522: Polysaccharide deacetylase; polysaccharide deacetylase 6039092..6039922 Streptomyces avermitilis MA-4680 1215645 NP_826168.1 CDS groES NC_003155.4 6040496 6040804 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 6040496..6040804 Streptomyces avermitilis MA-4680 1211169 NP_826169.1 CDS groEL NC_003155.4 6040941 6042569 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; chaperonin GroEL 6040941..6042569 Streptomyces avermitilis MA-4680 1211170 NP_826170.1 CDS SAV_4993 NC_003155.4 6042693 6043442 R PF07366: Protein of unknown function (DUF1486); hypothetical protein complement(6042693..6043442) Streptomyces avermitilis MA-4680 1215646 NP_826171.1 CDS SAV_4994 NC_003155.4 6043471 6044244 R PF00106: short chain dehydrogenase; dehydrogenase complement(6043471..6044244) Streptomyces avermitilis MA-4680 1215647 NP_826172.1 CDS SAV_4995 NC_003155.4 6044407 6045075 R PF03473: MOSC domain; hypothetical protein complement(6044407..6045075) Streptomyces avermitilis MA-4680 1215648 NP_826173.1 CDS SAV_4996 NC_003155.4 6045156 6046052 D LysR family transcriptional regulator 6045156..6046052 Streptomyces avermitilis MA-4680 1215649 NP_826174.1 CDS wblB NC_003155.4 6046179 6046508 R PF02467: Transcription factor WhiB; WhiB-family transcriptional regulator complement(6046179..6046508) Streptomyces avermitilis MA-4680 1211171 NP_826175.1 CDS SAV_4998 NC_003155.4 6046898 6047509 D two-component system response regulator 6046898..6047509 Streptomyces avermitilis MA-4680 1215650 NP_826176.1 CDS sig44 NC_003155.4 6047808 6048383 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase; RNA polymerase sigma factor SigD 6047808..6048383 Streptomyces avermitilis MA-4680 1211172 NP_826177.1 CDS guaB1 NC_003155.4 6048664 6050172 D inosine-5'-monophosphate dehydrogenase 6048664..6050172 Streptomyces avermitilis MA-4680 1211173 NP_826178.1 CDS guaB2 NC_003155.4 6050311 6051435 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 6050311..6051435 Streptomyces avermitilis MA-4680 1211174 NP_826179.1 CDS SAV_5002 NC_003155.4 6052108 6053316 R PF00984: UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase complement(6052108..6053316) Streptomyces avermitilis MA-4680 1215651 NP_826180.1 CDS glpD NC_003155.4 6053578 6055284 D glycerol-3-phosphate dehydrogenase 6053578..6055284 Streptomyces avermitilis MA-4680 1211175 NP_826181.1 CDS SAV_5004 NC_003155.4 6055377 6056438 R PF00144: Beta-lactamase; beta-lactamase complement(6055377..6056438) Streptomyces avermitilis MA-4680 1215652 NP_826182.1 CDS pkn18 NC_003155.4 6056589 6058769 D serine/threonine protein kinase 6056589..6058769 Streptomyces avermitilis MA-4680 1211176 NP_826183.1 CDS pkn19 NC_003155.4 6058940 6061621 D serine/threonine protein kinase 6058940..6061621 Streptomyces avermitilis MA-4680 1211177 NP_826184.1 CDS pkn20 NC_003155.4 6061938 6063581 D serine/threonine protein kinase 6061938..6063581 Streptomyces avermitilis MA-4680 1211178 NP_826185.1 CDS pkn21 NC_003155.4 6063790 6064947 D serine/threonine protein kinase 6063790..6064947 Streptomyces avermitilis MA-4680 1211179 NP_826186.1 CDS SAV_5009 NC_003155.4 6065086 6065475 D hypothetical protein 6065086..6065475 Streptomyces avermitilis MA-4680 1215653 NP_826187.1 CDS pkn22 NC_003155.4 6065586 6067322 D serine/threonine protein kinase 6065586..6067322 Streptomyces avermitilis MA-4680 1211180 NP_826188.1 CDS SAV_5011 NC_003155.4 6067364 6068167 R hypothetical protein complement(6067364..6068167) Streptomyces avermitilis MA-4680 1215654 NP_826189.1 CDS SAV_5012 NC_003155.4 6068609 6068794 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6068609..6068794) Streptomyces avermitilis MA-4680 1215655 NP_826190.1 CDS SAV_5013 NC_003155.4 6068806 6069657 R DNA-binding protein complement(6068806..6069657) Streptomyces avermitilis MA-4680 1215656 NP_826191.1 CDS SAV_5014 NC_003155.4 6069909 6070397 D regulatory protein 6069909..6070397 Streptomyces avermitilis MA-4680 1215657 NP_826192.1 CDS SAV_5015 NC_003155.4 6070502 6071875 D PF00781: Diacylglycerol kinase catalytic domain (presumed); hypothetical protein 6070502..6071875 Streptomyces avermitilis MA-4680 1215658 NP_826193.1 CDS gabD2 NC_003155.4 6072117 6073748 D NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase 6072117..6073748 Streptomyces avermitilis MA-4680 1215659 NP_826194.1 CDS choD NC_003155.4 6073813 6075618 D PF01266: FAD dependent oxidoreductase; cholesterol oxidase 6073813..6075618 Streptomyces avermitilis MA-4680 1215660 NP_826195.1 CDS SAV_5018 NC_003155.4 6075922 6076683 D hypothetical protein 6075922..6076683 Streptomyces avermitilis MA-4680 1215661 NP_826196.1 CDS SAV_5019 NC_003155.4 6077378 6077662 R hypothetical protein complement(6077378..6077662) Streptomyces avermitilis MA-4680 1215662 NP_826197.1 CDS SAV_5020 NC_003155.4 6077928 6078473 R PF04138: GtrA-like protein; hypothetical protein complement(6077928..6078473) Streptomyces avermitilis MA-4680 1215663 NP_826198.1 CDS purK NC_003155.4 6078590 6079813 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 6078590..6079813 Streptomyces avermitilis MA-4680 1211181 NP_826199.1 CDS purE NC_003155.4 6079810 6080343 D phosphoribosylaminoimidazole carboxylase catalytic subunit 6079810..6080343 Streptomyces avermitilis MA-4680 1211182 NP_826200.1 CDS SAV_5023 NC_003155.4 6080349 6081542 D PF01244: Membrane dipeptidase (Peptidase family M19); dipeptidase 6080349..6081542 Streptomyces avermitilis MA-4680 1215664 NP_826201.1 CDS SAV_5024 NC_003155.4 6081579 6081971 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(6081579..6081971) Streptomyces avermitilis MA-4680 1215665 NP_826202.1 CDS udgA NC_003155.4 6082205 6083548 R UDP-glucose 6-dehydrogenase complement(6082205..6083548) Streptomyces avermitilis MA-4680 1211183 NP_826203.1 CDS fadE1 NC_003155.4 6083724 6084881 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 6083724..6084881 Streptomyces avermitilis MA-4680 1211184 NP_826204.1 CDS SAV_5027 NC_003155.4 6084970 6085605 R PF00702: haloacid dehalogenase-like hydrolase; hypothetical protein complement(6084970..6085605) Streptomyces avermitilis MA-4680 1215666 NP_826205.1 CDS SAV_5028 NC_003155.4 6085605 6086798 R PF03816: Cell envelope-related transcriptional attenuator domain; transcriptional regulator complement(6085605..6086798) Streptomyces avermitilis MA-4680 1215667 NP_826206.1 CDS SAV_5029 NC_003155.4 6086994 6087617 D PF03061: Thioesterase superfamily; acyl-CoA hydrolase 6086994..6087617 Streptomyces avermitilis MA-4680 1215668 NP_826207.1 CDS SAV_5030 NC_003155.4 6087680 6089206 R PF03816: Cell envelope-related transcriptional attenuator domain; transcriptional regulator complement(6087680..6089206) Streptomyces avermitilis MA-4680 1215669 NP_826208.1 CDS SAV_5031 NC_003155.4 6089279 6090307 D PF00535: Glycosyl transferase; glycosyl transferase 6089279..6090307 Streptomyces avermitilis MA-4680 1215670 NP_826209.1 CDS SAV_5032 NC_003155.4 6090362 6092104 R PF03816: Cell envelope-related transcriptional attenuator domain; transcriptional regulator complement(6090362..6092104) Streptomyces avermitilis MA-4680 1215671 NP_826210.1 CDS SAV_5033 NC_003155.4 6092429 6093952 R PF03816: Cell envelope-related transcriptional attenuator domain; transcriptional regulator complement(6092429..6093952) Streptomyces avermitilis MA-4680 1215672 NP_826211.1 CDS SAV_5034 NC_003155.4 6094412 6095662 R PF03816: Cell envelope-related transcriptional attenuator domain; transcriptional regulator complement(6094412..6095662) Streptomyces avermitilis MA-4680 1215673 NP_826212.1 CDS SAV_5035 NC_003155.4 6095910 6096674 R hypothetical protein complement(6095910..6096674) Streptomyces avermitilis MA-4680 1215674 NP_826213.1 CDS SAV_5036 NC_003155.4 6096814 6098190 D PF01510: N-acetylmuramoyl-L-alanine amidase; hypothetical protein 6096814..6098190 Streptomyces avermitilis MA-4680 1215675 NP_826214.1 CDS rmlA NC_003155.4 6098346 6099428 D PF00483: Nucleotidyl transferase; nucleotide phosphorylase 6098346..6099428 Streptomyces avermitilis MA-4680 1211185 NP_826215.1 CDS SAV_5038 NC_003155.4 6099570 6100580 R hypothetical protein complement(6099570..6100580) Streptomyces avermitilis MA-4680 1215676 NP_826216.1 CDS SAV_5039 NC_003155.4 6100654 6101925 R catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0); F420-0--gamma-glutamyl ligase complement(6100654..6101925) Streptomyces avermitilis MA-4680 1215677 NP_826217.1 CDS SAV_5040 NC_003155.4 6102195 6103154 R catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); LPPG:FO 2-phospho-L-lactate transferase complement(6102195..6103154) Streptomyces avermitilis MA-4680 1215678 NP_826218.1 CDS cdo2 NC_003155.4 6103189 6103716 R PF05995: cysteine dioxygenase type I; cysteine dioxygenase complement(6103189..6103716) Streptomyces avermitilis MA-4680 1215679 NP_826219.1 CDS whiB NC_003155.4 6104412 6104675 D PF02467: Transcription factor WhiB; WhiB-family transcriptional regulator 6104412..6104675 Streptomyces avermitilis MA-4680 1211186 NP_826220.1 CDS SAV_5043 NC_003155.4 6104897 6108574 D PF00535: Glycosyl transferase; hypothetical protein 6104897..6108574 Streptomyces avermitilis MA-4680 1215680 NP_826221.1 CDS SAV_5044 NC_003155.4 6108571 6110079 D protein 6108571..6110079 Streptomyces avermitilis MA-4680 1215681 NP_826222.1 CDS SAV_5045 NC_003155.4 6110158 6110730 R hypothetical protein complement(6110158..6110730) Streptomyces avermitilis MA-4680 1215682 NP_826223.1 CDS SAV_5046 NC_003155.4 6110912 6111385 D hypothetical protein 6110912..6111385 Streptomyces avermitilis MA-4680 1215683 NP_826224.1 CDS lldP NC_003155.4 6111641 6113257 D L-lactate permease 6111641..6113257 Streptomyces avermitilis MA-4680 1215684 NP_826225.1 CDS manB NC_003155.4 6113505 6114872 D converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase 6113505..6114872 Streptomyces avermitilis MA-4680 1211187 NP_826226.1 CDS SAV_5049 NC_003155.4 6115063 6115233 D PF03966: Protein of unknown function (DUF343); hypothetical protein 6115063..6115233 Streptomyces avermitilis MA-4680 1215685 NP_826227.1 CDS SAV_5050 NC_003155.4 6115265 6116392 D hypothetical protein 6115265..6116392 Streptomyces avermitilis MA-4680 1215686 NP_826228.1 CDS manA NC_003155.4 6116496 6117647 D mannose-6-phosphate isomerase 6116496..6117647 Streptomyces avermitilis MA-4680 1211188 NP_826229.1 CDS SAV_5052 NC_003155.4 6117765 6118748 D transport protein 6117765..6118748 Streptomyces avermitilis MA-4680 1215687 NP_826230.1 CDS sahH NC_003155.4 6119333 6120790 D catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 6119333..6120790 Streptomyces avermitilis MA-4680 1211189 NP_826231.1 CDS SAV_5054 NC_003155.4 6120938 6121552 D PF06271: RDD family; hypothetical protein 6120938..6121552 Streptomyces avermitilis MA-4680 1215688 NP_826232.1 CDS SAV_5055 NC_003155.4 6121647 6122654 R PF06271: RDD family; hypothetical protein complement(6121647..6122654) Streptomyces avermitilis MA-4680 1215689 NP_826233.1 CDS SAV_5056 NC_003155.4 6122773 6123780 D PF01944: Integral membrane protein DUF95; hypothetical protein 6122773..6123780 Streptomyces avermitilis MA-4680 1215690 NP_826234.1 CDS SAV_5057 NC_003155.4 6129669 6130979 R PF01882: Protein of unknown function DUF58; hypothetical protein complement(6129669..6130979) Streptomyces avermitilis MA-4680 1215691 NP_826235.1 CDS SAV_5058 NC_003155.4 6130979 6131971 R regulatory protein complement(6130979..6131971) Streptomyces avermitilis MA-4680 1215692 NP_826236.1 CDS SAV_5059 NC_003155.4 6131968 6133107 R protein complement(6131968..6133107) Streptomyces avermitilis MA-4680 1215693 NP_826237.1 CDS SAV_5060 NC_003155.4 6133158 6133877 R integral membrane protein complement(6133158..6133877) Streptomyces avermitilis MA-4680 1215694 NP_826238.1 CDS SAV_5061 NC_003155.4 6133912 6135261 R PF07415: Gammaherpesvirus latent membrane protein (LMP2) protein; integral membrane protein complement(6133912..6135261) Streptomyces avermitilis MA-4680 1215695 NP_826239.1 CDS eif1 NC_003155.4 6135405 6136553 D initiation factor eIF-2B alpha subunit 6135405..6136553 Streptomyces avermitilis MA-4680 1211193 NP_826240.1 CDS SAV_5063 NC_003155.4 6136558 6137247 D two-component system response regulator 6136558..6137247 Streptomyces avermitilis MA-4680 1215696 NP_826241.1 CDS SAV_5064 NC_003155.4 6137249 6139327 D two-component system sensor kinase 6137249..6139327 Streptomyces avermitilis MA-4680 1215697 NP_826242.1 CDS SAV_5065 NC_003155.4 6139317 6141149 D lipoprotein LpqB 6139317..6141149 Streptomyces avermitilis MA-4680 1215698 NP_826243.1 CDS SAV_5066 NC_003155.4 6141156 6142175 D PF00156: Phosphoribosyl transferase domain; hypothetical protein 6141156..6142175 Streptomyces avermitilis MA-4680 1215699 NP_826244.1 CDS SAV_5067 NC_003155.4 6142323 6143183 D PF02482: Sigma 54 modulation protein / S30EA ribosomal protein; hypothetical protein 6142323..6143183 Streptomyces avermitilis MA-4680 1215700 NP_826245.1 CDS SAV_5068 NC_003155.4 6143389 6144135 D two-component system response regulator 6143389..6144135 Streptomyces avermitilis MA-4680 1215701 NP_826246.1 CDS SAV_5069 NC_003155.4 6144163 6145365 R PF06224: Protein of unknown function (DUF1006); hypothetical protein complement(6144163..6145365) Streptomyces avermitilis MA-4680 1215702 NP_826247.1 CDS SAV_5070 NC_003155.4 6145429 6145998 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(6145429..6145998) Streptomyces avermitilis MA-4680 1215703 NP_826248.1 CDS secA1 NC_003155.4 6146233 6149052 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 6146233..6149052 Streptomyces avermitilis MA-4680 1211194 NP_826249.1 CDS SAV_5072 NC_003155.4 6149247 6149516 R hypothetical protein complement(6149247..6149516) Streptomyces avermitilis MA-4680 1215704 NP_826250.1 CDS SAV_5073 NC_003155.4 6150095 6150610 D hypothetical protein 6150095..6150610 Streptomyces avermitilis MA-4680 1215705 NP_826251.1 CDS SAV_5074 NC_003155.4 6150756 6151430 D phosphatase 6150756..6151430 Streptomyces avermitilis MA-4680 1215706 NP_826252.1 CDS SAV_5075 NC_003155.4 6152169 6157106 D PF05088: Bacterial NAD-glutamate dehydrogenase; NAD-glutamate dehydrogenase 6152169..6157106 Streptomyces avermitilis MA-4680 1215707 NP_826253.1 CDS SAV_5076 NC_003155.4 6157319 6157807 D PF04138: GtrA-like protein; hypothetical protein 6157319..6157807 Streptomyces avermitilis MA-4680 1215708 NP_826254.1 CDS SAV_5077 NC_003155.4 6157791 6159287 D integral membrane protein 6157791..6159287 Streptomyces avermitilis MA-4680 1215709 NP_826255.1 CDS SAV_5078 NC_003155.4 6159441 6161141 R transferase complement(6159441..6161141) Streptomyces avermitilis MA-4680 1215710 NP_826256.1 CDS tagF NC_003155.4 6161138 6163360 R CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase complement(6161138..6163360) Streptomyces avermitilis MA-4680 1211195 NP_826257.1 CDS tagH NC_003155.4 6163464 6164453 R teichoic acid translocation transport system; ABC transporter ATP-binding protein complement(6163464..6164453) Streptomyces avermitilis MA-4680 1211196 NP_826258.1 CDS SAV_5081 NC_003155.4 6164446 6165405 R ABC transporter permease complement(6164446..6165405) Streptomyces avermitilis MA-4680 1215711 NP_826259.1 CDS SAV_5082 NC_003155.4 6165643 6166281 D TetR family transcriptional regulator 6165643..6166281 Streptomyces avermitilis MA-4680 1215712 NP_826260.1 CDS SAV_5083 NC_003155.4 6166489 6167544 R PF03747: ADP-ribosylglycohydrolase; ribosylglycoyhydrolase complement(6166489..6167544) Streptomyces avermitilis MA-4680 1215713 NP_826261.1 CDS SAV_5084 NC_003155.4 6167549 6168172 R TetR family transcriptional regulator complement(6167549..6168172) Streptomyces avermitilis MA-4680 1215714 NP_826262.1 CDS SAV_5085 NC_003155.4 6168271 6169239 D PF00106: short chain dehydrogenase; dehydrogenase 6168271..6169239 Streptomyces avermitilis MA-4680 1215715 NP_826263.1 CDS galE3 NC_003155.4 6169307 6170287 R UDP-glucose 4-epimerase complement(6169307..6170287) Streptomyces avermitilis MA-4680 1211197 NP_826264.1 CDS SAV_5087 NC_003155.4 6170365 6171960 R transferase complement(6170365..6171960) Streptomyces avermitilis MA-4680 1215716 NP_826265.1 CDS SAV_5088 NC_003155.4 6172005 6173273 R hypothetical protein complement(6172005..6173273) Streptomyces avermitilis MA-4680 1215717 NP_826266.1 CDS SAV_5089 NC_003155.4 6173367 6174929 D hypothetical protein 6173367..6174929 Streptomyces avermitilis MA-4680 1215718 NP_826267.1 CDS SAV_5090 NC_003155.4 6175007 6175510 R MarR family transcriptional regulator complement(6175007..6175510) Streptomyces avermitilis MA-4680 1215719 NP_826268.1 CDS ohrB2 NC_003155.4 6175639 6176052 D organic hydroperoxide resistance protein 6175639..6176052 Streptomyces avermitilis MA-4680 1215720 NP_826269.1 CDS SAV_5092 NC_003155.4 6176259 6177581 R integral membrane protein complement(6176259..6177581) Streptomyces avermitilis MA-4680 1215721 NP_826270.1 CDS SAV_5093 NC_003155.4 6177590 6179788 R PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; glycosyl transferase complement(6177590..6179788) Streptomyces avermitilis MA-4680 1215722 NP_826271.1 CDS SAV_5094 NC_003155.4 6179794 6181983 R PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; glycosyl transferase complement(6179794..6181983) Streptomyces avermitilis MA-4680 1215723 NP_826272.1 CDS SAV_5095 NC_003155.4 6182113 6184449 R PF04464: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; glycosyl transferase complement(6182113..6184449) Streptomyces avermitilis MA-4680 1215724 NP_826273.1 CDS SAV_5096 NC_003155.4 6184571 6185452 R sugar ABC transporter permease complement(6184571..6185452) Streptomyces avermitilis MA-4680 1215725 NP_826274.1 CDS SAV_5097 NC_003155.4 6185449 6186729 R sugar ABC transporter permease complement(6185449..6186729) Streptomyces avermitilis MA-4680 1215726 NP_826275.1 CDS SAV_5098 NC_003155.4 6186823 6188214 R sugar ABC transporter substrate-binding protein complement(6186823..6188214) Streptomyces avermitilis MA-4680 1215727 NP_826276.1 CDS SAV_5099 NC_003155.4 6188365 6192633 R PF00498: FHA domain; hypothetical protein complement(6188365..6192633) Streptomyces avermitilis MA-4680 1215728 NP_826277.1 CDS pkn23 NC_003155.4 6193092 6194813 D serine/threonine protein kinase 6193092..6194813 Streptomyces avermitilis MA-4680 1211198 NP_826278.1 CDS pkn24 NC_003155.4 6194969 6196210 D serine/threonine protein kinase 6194969..6196210 Streptomyces avermitilis MA-4680 1211199 NP_826279.1 CDS prfB NC_003155.4 6196323 6197429 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 6196323..6197429 Streptomyces avermitilis MA-4680 1211200 NP_826280.1 CDS SAV_5103 NC_003155.4 6197736 6198566 D protein 6197736..6198566 Streptomyces avermitilis MA-4680 1215729 NP_826281.1 CDS ftsE NC_003155.4 6199189 6199878 D ABC transporter ATP-binding protein; cell division ATP-binding protein 6199189..6199878 Streptomyces avermitilis MA-4680 1211201 NP_826282.1 CDS ftsX NC_003155.4 6199908 6200825 D cell division protein 6199908..6200825 Streptomyces avermitilis MA-4680 1211202 NP_826283.1 CDS SAV_5106 NC_003155.4 6200893 6202062 D PF03572: Peptidase family S41; carboxy-terminal processing protease precursor 6200893..6202062 Streptomyces avermitilis MA-4680 1215730 NP_826284.1 CDS smpB NC_003155.4 6202121 6202654 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 6202121..6202654 Streptomyces avermitilis MA-4680 1211203 NP_826285.1 CDS SAV_5108 NC_003155.4 6203529 6204158 D hypothetical protein 6203529..6204158 Streptomyces avermitilis MA-4680 1215731 NP_826286.1 CDS SAV_5109 NC_003155.4 6204339 6204635 R hypothetical protein complement(6204339..6204635) Streptomyces avermitilis MA-4680 1215732 NP_826287.1 CDS SAV_5110 NC_003155.4 6205038 6205949 D phosphotransferase 6205038..6205949 Streptomyces avermitilis MA-4680 1215733 NP_826288.1 CDS cyp21 NC_003155.4 6206060 6207481 D CYP184A1; cytochrome P450 6206060..6207481 Streptomyces avermitilis MA-4680 1211205 NP_826289.1 CDS SAV_5112 NC_003155.4 6207447 6208703 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(6207447..6208703) Streptomyces avermitilis MA-4680 1215734 NP_826290.1 CDS SAV_5113 NC_003155.4 6208934 6209899 D LysR family transcriptional regulator 6208934..6209899 Streptomyces avermitilis MA-4680 1215735 NP_826291.1 CDS SAV_5114 NC_003155.4 6209993 6211513 D hypothetical protein 6209993..6211513 Streptomyces avermitilis MA-4680 1215736 NP_826292.1 CDS SAV_5115 NC_003155.4 6211513 6213765 D bi-functional transferase/deacetylase 6211513..6213765 Streptomyces avermitilis MA-4680 1215737 NP_826293.1 CDS SAV_5116 NC_003155.4 6213762 6215018 D PF01757: Acyltransferase family; integral membrane protein 6213762..6215018 Streptomyces avermitilis MA-4680 1215738 NP_826294.1 CDS SAV_5117 NC_003155.4 6215339 6215887 R hypothetical protein complement(6215339..6215887) Streptomyces avermitilis MA-4680 1215739 NP_826295.1 CDS SAV_5118 NC_003155.4 6216000 6216446 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(6216000..6216446) Streptomyces avermitilis MA-4680 1215740 NP_826296.1 CDS narK NC_003155.4 6216715 6218106 D PF07690: Major Facilitator Superfamily; nitrate extrusion protein 6216715..6218106 Streptomyces avermitilis MA-4680 1211206 NP_826297.1 CDS SAV_5120 NC_003155.4 6218210 6219370 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 6218210..6219370 Streptomyces avermitilis MA-4680 1215741 NP_826298.1 CDS SAV_5121 NC_003155.4 6219319 6219873 R hypothetical protein complement(6219319..6219873) Streptomyces avermitilis MA-4680 1215742 NP_826299.1 CDS SAV_5122 NC_003155.4 6220123 6220710 D PF07336: Protein of unknown function (DUF1470); hypothetical protein 6220123..6220710 Streptomyces avermitilis MA-4680 1215743 NP_826300.1 CDS sig45 NC_003155.4 6221200 6221796 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and or membrane proteins; RNA polymerase sigma factor SigL 6221200..6221796 Streptomyces avermitilis MA-4680 1211207 NP_826301.1 CDS SAV_5124 NC_003155.4 6221799 6222617 D hypothetical protein 6221799..6222617 Streptomyces avermitilis MA-4680 1215744 NP_826302.1 CDS SAV_5125 NC_003155.4 6222701 6225211 D ATP-dependent helicase 6222701..6225211 Streptomyces avermitilis MA-4680 1215745 NP_826303.1 CDS SAV_5126 NC_003155.4 6225718 6227151 D PF03949: Malic enzyme, NAD binding domain; malate oxidoreductase 6225718..6227151 Streptomyces avermitilis MA-4680 1215746 NP_826304.1 CDS hup NC_003155.4 6227508 6227789 D PF00216: Bacterial DNA-binding protein; DNA-binding protein HU 1 6227508..6227789 Streptomyces avermitilis MA-4680 1211208 NP_826305.1 CDS murA2 NC_003155.4 6227970 6229316 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(6227970..6229316) Streptomyces avermitilis MA-4680 1211209 NP_826306.1 CDS SAV_5129 NC_003155.4 6229586 6230167 D PF02622: Uncharacterized ACR, COG1678; hypothetical protein 6229586..6230167 Streptomyces avermitilis MA-4680 1215747 NP_826307.1 CDS SAV_5130 NC_003155.4 6230197 6230493 D hypothetical protein 6230197..6230493 Streptomyces avermitilis MA-4680 1215748 NP_826308.1 CDS SAV_5131 NC_003155.4 6230779 6232119 D sugar ABC transporter substrate-binding protein 6230779..6232119 Streptomyces avermitilis MA-4680 1215749 NP_826309.1 CDS SAV_5132 NC_003155.4 6232124 6233086 D sugar ABC transporter permease 6232124..6233086 Streptomyces avermitilis MA-4680 1215750 NP_826310.1 CDS SAV_5133 NC_003155.4 6233083 6233928 D sugar ABC transporter permease 6233083..6233928 Streptomyces avermitilis MA-4680 1215751 NP_826311.1 CDS nagZ3 NC_003155.4 6233930 6235663 D beta-N-acetylhexosaminidase 6233930..6235663 Streptomyces avermitilis MA-4680 1215752 NP_826312.1 CDS SAV_5135 NC_003155.4 6235873 6236793 D PF00941: FAD binding domain in molybdopterin dehydrogenase; dehydrogenase 6235873..6236793 Streptomyces avermitilis MA-4680 1215753 NP_826313.1 CDS SAV_5136 NC_003155.4 6236790 6238352 D PF01799: [2Fe-2S] binding domain; hypothetical protein 6236790..6238352 Streptomyces avermitilis MA-4680 1215754 NP_826314.1 CDS SAV_5137 NC_003155.4 6238349 6240655 D PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; dehydrogenase 6238349..6240655 Streptomyces avermitilis MA-4680 1215755 NP_826315.1 CDS SAV_5138 NC_003155.4 6240993 6242183 D hypothetical protein 6240993..6242183 Streptomyces avermitilis MA-4680 1215756 NP_826316.1 CDS ebrB NC_003155.4 6242641 6244095 D PF07690: Major Facilitator Superfamily; multidrug resistance efflux protein 6242641..6244095 Streptomyces avermitilis MA-4680 1211211 NP_826317.1 CDS sdrA NC_003155.4 6244408 6246204 D PF04851: Type III restriction enzyme, res subunit; protein involving differentiation 6244408..6246204 Streptomyces avermitilis MA-4680 1211212 NP_826318.1 CDS sdrB NC_003155.4 6246638 6247279 D PF01614: Bacterial transcriptional regulator; differentiation regulon transcriptional regulator 6246638..6247279 Streptomyces avermitilis MA-4680 1211213 NP_826319.1 CDS sdrC NC_003155.4 6247582 6248376 D PF05362: Lon protease (S16) C-terminal proteolytic domain; protein 6247582..6248376 Streptomyces avermitilis MA-4680 1211214 NP_826320.1 CDS SAV_5143 NC_003155.4 6248588 6249226 R transcription regulator ArsR complement(6248588..6249226) Streptomyces avermitilis MA-4680 1215757 NP_826321.1 CDS SAV_5144 NC_003155.4 6249242 6250204 R ABC transporter substrate-binding protein complement(6249242..6250204) Streptomyces avermitilis MA-4680 1215758 NP_826322.1 CDS SAV_5145 NC_003155.4 6250201 6251031 R ABC transporter permease complement(6250201..6251031) Streptomyces avermitilis MA-4680 1215759 NP_826323.1 CDS SAV_5146 NC_003155.4 6251028 6252341 R ABC transporter ATP-binding protein complement(6251028..6252341) Streptomyces avermitilis MA-4680 1215760 NP_826324.1 CDS SAV_5147 NC_003155.4 6252334 6252981 R ABC transporter permease complement(6252334..6252981) Streptomyces avermitilis MA-4680 1215761 NP_826325.1 CDS SAV_5148 NC_003155.4 6253005 6253517 R transcription regulator AsnC complement(6253005..6253517) Streptomyces avermitilis MA-4680 1215762 NP_826326.1 CDS hpd NC_003155.4 6253610 6254755 D ochronotic pigment biosynthesis, PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; 4-hydroxyphenylpyruvate dioxygenase 6253610..6254755 Streptomyces avermitilis MA-4680 1211215 NP_826327.1 CDS SAV_5150 NC_003155.4 6254901 6256490 R PF00515: TPR Domain; hypothetical protein complement(6254901..6256490) Streptomyces avermitilis MA-4680 1215763 NP_826328.1 CDS glcD2 NC_003155.4 6256583 6257998 D similar to glycolate oxidase: PF01565: FAD binding domain; (S)-2-hydroxy-acid oxidase 6256583..6257998 Streptomyces avermitilis MA-4680 1215764 NP_826329.1 CDS SAV_5152 NC_003155.4 6258237 6259847 D PF06271: RDD family; hypothetical protein 6258237..6259847 Streptomyces avermitilis MA-4680 1215765 NP_826330.1 CDS SAV_5153 NC_003155.4 6260266 6260712 D PF06271: RDD family; hypothetical protein 6260266..6260712 Streptomyces avermitilis MA-4680 1215766 NP_826331.1 CDS SAV_5154 NC_003155.4 6260892 6261176 R hypothetical protein complement(6260892..6261176) Streptomyces avermitilis MA-4680 1215767 NP_826332.1 CDS SAV_5155 NC_003155.4 6261636 6263981 D PF05547: Immune inhibitor A peptidase M6; protease 6261636..6263981 Streptomyces avermitilis MA-4680 1215768 NP_826333.1 CDS SAV_5156 NC_003155.4 6264103 6264486 D hypothetical protein 6264103..6264486 Streptomyces avermitilis MA-4680 1215769 NP_826334.1 CDS pncA NC_003155.4 6264870 6265454 R nicotinamidase complement(6264870..6265454) Streptomyces avermitilis MA-4680 1211216 NP_826335.1 CDS pncB NC_003155.4 6265776 6267104 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(6265776..6267104) Streptomyces avermitilis MA-4680 1211217 NP_826336.1 CDS clpS NC_003155.4 6267279 6267596 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 6267279..6267596 Streptomyces avermitilis MA-4680 1215770 NP_826337.1 CDS SAV_5160 NC_003155.4 6267609 6268214 D hypothetical protein 6267609..6268214 Streptomyces avermitilis MA-4680 1215771 NP_826338.1 CDS SAV_5161 NC_003155.4 6268547 6269998 D proline permease 6268547..6269998 Streptomyces avermitilis MA-4680 1215772 NP_826339.1 CDS SAV_5162 NC_003155.4 6270089 6270511 D PF01398: Mov34/MPN/PAD-1 family; hypothetical protein 6270089..6270511 Streptomyces avermitilis MA-4680 1215773 NP_826340.1 CDS SAV_5163 NC_003155.4 6270890 6271177 D PF02597: ThiS family; hypothetical protein 6270890..6271177 Streptomyces avermitilis MA-4680 1215774 NP_826341.1 CDS cysM2 NC_003155.4 6271195 6272145 D cysteine synthase 6271195..6272145 Streptomyces avermitilis MA-4680 1211218 NP_826342.1 CDS SAV_5165 NC_003155.4 6272273 6272719 R hypothetical protein complement(6272273..6272719) Streptomyces avermitilis MA-4680 1215775 NP_826343.1 CDS SAV_5166 NC_003155.4 6272994 6273746 D PF00753: Metallo-beta-lactamase superfamily; hypothetical protein 6272994..6273746 Streptomyces avermitilis MA-4680 1215776 NP_826344.1 CDS ptsC1 NC_003155.4 6273825 6275093 R PF02378: Phosphotransferase system, EIIC; phosphotransferase system IIC component complement(6273825..6275093) Streptomyces avermitilis MA-4680 1215777 NP_826345.1 CDS ptsC2 NC_003155.4 6275343 6276629 R PF02378: Phosphotransferase system, EIIC; phosphotransferase system IIC component complement(6275343..6276629) Streptomyces avermitilis MA-4680 1215778 NP_826346.1 CDS ptsB NC_003155.4 6276799 6277032 D PF00367: Phosphotransferase system, EIIB; phosphotransferase system IIB component 6276799..6277032 Streptomyces avermitilis MA-4680 1215779 NP_826347.1 CDS rph NC_003155.4 6277137 6277871 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 6277137..6277871 Streptomyces avermitilis MA-4680 1211219 NP_826348.1 CDS SAV_5171 NC_003155.4 6277931 6278347 D protein 6277931..6278347 Streptomyces avermitilis MA-4680 1215780 NP_826349.1 CDS SAV_5172 NC_003155.4 6278382 6278984 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 6278382..6278984 Streptomyces avermitilis MA-4680 1215781 NP_826350.1 CDS SAV_5173 NC_003155.4 6279261 6280244 R PF00561: alpha/beta hydrolase fold; hydrolase complement(6279261..6280244) Streptomyces avermitilis MA-4680 1215782 NP_826351.1 CDS SAV_5174 NC_003155.4 6280352 6280963 D TetR family transcriptional regulator 6280352..6280963 Streptomyces avermitilis MA-4680 1215783 NP_826352.1 CDS SAV_5175 NC_003155.4 6281141 6282649 R PF00083: Sugar (and other) transporter; osmoprotectant transporter complement(6281141..6282649) Streptomyces avermitilis MA-4680 1215784 NP_826353.1 CDS bcp2 NC_003155.4 6282777 6283244 R PF00578: AhpC/TSA family; bacterioferritin comigratory protein complement(6282777..6283244) Streptomyces avermitilis MA-4680 1211221 NP_826354.1 CDS SAV_5177 NC_003155.4 6283437 6283775 D hypothetical protein 6283437..6283775 Streptomyces avermitilis MA-4680 1215785 NP_826355.1 CDS groES2 NC_003155.4 6283819 6284175 D GroES family molecular chaperone 6283819..6284175 Streptomyces avermitilis MA-4680 1211222 NP_826356.1 CDS pbp9 NC_003155.4 6284295 6286541 R PF00912: Transglycosylase; penicillin-binding protein complement(6284295..6286541) Streptomyces avermitilis MA-4680 1211223 NP_826357.1 CDS SAV_5180 NC_003155.4 6286890 6287690 D PF06182: Protein of unknown function (DUF990); hypothetical protein 6286890..6287690 Streptomyces avermitilis MA-4680 1215786 NP_826358.1 CDS SAV_5181 NC_003155.4 6287683 6288582 D PF06182: Protein of unknown function (DUF990); integral membrane transport protein 6287683..6288582 Streptomyces avermitilis MA-4680 1215787 NP_826359.1 CDS SAV_5182 NC_003155.4 6288585 6289592 D ABC transporter ATP-binding protein 6288585..6289592 Streptomyces avermitilis MA-4680 1215788 NP_826360.1 CDS SAV_5183 NC_003155.4 6289626 6290528 D hypothetical protein 6289626..6290528 Streptomyces avermitilis MA-4680 1215789 NP_826361.1 CDS SAV_5184 NC_003155.4 6290569 6291963 R PF00657: GDSL-like Lipase/Acylhydrolase; protein complement(6290569..6291963) Streptomyces avermitilis MA-4680 1215790 NP_826362.1 CDS SAV_5185 NC_003155.4 6292063 6293430 D PF04286: Protein of unknown function (DUF445); hypothetical protein 6292063..6293430 Streptomyces avermitilis MA-4680 1215791 NP_826363.1 CDS SAV_5186 NC_003155.4 6293494 6294999 D PF07690: Major Facilitator Superfamily; sugar transport protein 6293494..6294999 Streptomyces avermitilis MA-4680 1215792 NP_826364.1 CDS SAV_5187 NC_003155.4 6295078 6295557 D hypothetical protein 6295078..6295557 Streptomyces avermitilis MA-4680 1215793 NP_826365.1 CDS SAV_5188 NC_003155.4 6295642 6296151 R hypothetical protein complement(6295642..6296151) Streptomyces avermitilis MA-4680 1215794 NP_826366.1 CDS SAV_5189 NC_003155.4 6296162 6296611 R integral membrane protein complement(6296162..6296611) Streptomyces avermitilis MA-4680 1215795 NP_826367.1 CDS SAV_5190 NC_003155.4 6296882 6297907 D AraC family transcription regulator 6296882..6297907 Streptomyces avermitilis MA-4680 1215796 NP_826368.1 CDS SAV_5191 NC_003155.4 6297984 6298289 R hypothetical protein complement(6297984..6298289) Streptomyces avermitilis MA-4680 1215797 NP_826369.1 CDS SAV_5192 NC_003155.4 6298444 6299172 R hypothetical protein complement(6298444..6299172) Streptomyces avermitilis MA-4680 1215798 NP_826370.1 CDS SAV_5193 NC_003155.4 6299385 6299759 R PF03995: Peptidase inhibitor family I36; hypothetical protein complement(6299385..6299759) Streptomyces avermitilis MA-4680 1215799 NP_826371.1 CDS SAV_5194 NC_003155.4 6299976 6300449 R hypothetical protein complement(6299976..6300449) Streptomyces avermitilis MA-4680 1215800 NP_826372.1 CDS SAV_5195 NC_003155.4 6301008 6301202 D hypothetical protein 6301008..6301202 Streptomyces avermitilis MA-4680 1215801 NP_826373.1 CDS SAV_5196 NC_003155.4 6301177 6301710 D hypothetical protein 6301177..6301710 Streptomyces avermitilis MA-4680 1215802 NP_826374.1 CDS SAV_5197 NC_003155.4 6301736 6302587 D DNA-binding protein 6301736..6302587 Streptomyces avermitilis MA-4680 1215803 NP_826375.1 CDS SAV_5198 NC_003155.4 6302630 6303106 R hypothetical protein complement(6302630..6303106) Streptomyces avermitilis MA-4680 1215804 NP_826376.1 CDS SAV_5199 NC_003155.4 6303268 6303480 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6303268..6303480) Streptomyces avermitilis MA-4680 1215805 NP_826377.1 CDS SAV_5200 NC_003155.4 6303477 6304325 R DNA-binding protein complement(6303477..6304325) Streptomyces avermitilis MA-4680 1215806 NP_826378.1 CDS SAV_5201 NC_003155.4 6304532 6305194 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein 6304532..6305194 Streptomyces avermitilis MA-4680 1215807 NP_826379.1 CDS SAV_5202 NC_003155.4 6305198 6308119 R ATP-dependent helicase complement(6305198..6308119) Streptomyces avermitilis MA-4680 1215808 NP_826380.1 CDS SAV_5203 NC_003155.4 6309050 6309583 D hypothetical protein 6309050..6309583 Streptomyces avermitilis MA-4680 1215809 NP_826381.1 CDS SAV_5204 NC_003155.4 6309631 6310644 R PF02810: SEC-C motif; hypothetical protein complement(6309631..6310644) Streptomyces avermitilis MA-4680 1215810 NP_826382.1 CDS SAV_5205 NC_003155.4 6310847 6312322 R endo-beta-1,6-galactanase complement(6310847..6312322) Streptomyces avermitilis MA-4680 1215811 NP_826383.1 CDS SAV_5206 NC_003155.4 6312601 6313419 D PF04203: Sortase family; hypothetical protein 6312601..6313419 Streptomyces avermitilis MA-4680 1215812 NP_826384.1 CDS SAV_5207 NC_003155.4 6313586 6313921 D hypothetical protein 6313586..6313921 Streptomyces avermitilis MA-4680 1215813 NP_826385.1 CDS SAV_5208 NC_003155.4 6314034 6314765 D PF02096: 60Kd inner membrane protein; hypothetical protein 6314034..6314765 Streptomyces avermitilis MA-4680 1215814 NP_826386.1 CDS hpcE NC_003155.4 6314908 6315765 D 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 6314908..6315765 Streptomyces avermitilis MA-4680 1211224 NP_826387.1 CDS SAV_5210 NC_003155.4 6315925 6316416 R PF06142: Protein of unknown function (DUF967); hypothetical protein complement(6315925..6316416) Streptomyces avermitilis MA-4680 1215815 NP_826388.1 CDS SAV_5211 NC_003155.4 6316485 6317579 R PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase complement(6316485..6317579) Streptomyces avermitilis MA-4680 1215816 NP_826389.1 CDS SAV_5212 NC_003155.4 6317639 6318925 D transcriptional regulator 6317639..6318925 Streptomyces avermitilis MA-4680 1215817 NP_826390.1 CDS SAV_5213 NC_003155.4 6319187 6320206 D hypothetical protein 6319187..6320206 Streptomyces avermitilis MA-4680 1215818 NP_826391.1 CDS SAV_5214 NC_003155.4 6320308 6321087 D N-acetyl-glucosamine catabolism protein 6320308..6321087 Streptomyces avermitilis MA-4680 1215819 NP_826392.1 CDS SAV_5215 NC_003155.4 6321293 6321940 D hypothetical protein 6321293..6321940 Streptomyces avermitilis MA-4680 1215820 NP_826393.1 CDS SAV_5216 NC_003155.4 6322057 6322722 D PF04203: Sortase family; hypothetical protein 6322057..6322722 Streptomyces avermitilis MA-4680 1215821 NP_826394.1 CDS SAV_5217 NC_003155.4 6323049 6324065 D endo-1,4-beta-glucanase 6323049..6324065 Streptomyces avermitilis MA-4680 1215822 NP_826395.1 CDS SAV_5218 NC_003155.4 6324186 6326123 R PF07646: Kelch motif; protein complement(6324186..6326123) Streptomyces avermitilis MA-4680 1215823 NP_826396.1 CDS SAV_5219 NC_003155.4 6326120 6328114 R PF00535: Glycosyl transferase; glycosyl transferase complement(6326120..6328114) Streptomyces avermitilis MA-4680 1215824 NP_826397.1 CDS SAV_5220 NC_003155.4 6328439 6329161 R GntR family transcriptional regulator complement(6328439..6329161) Streptomyces avermitilis MA-4680 1215825 NP_826398.1 CDS SAV_5221 NC_003155.4 6329508 6330707 D PF00877: NlpC/P60 family; hypothetical protein 6329508..6330707 Streptomyces avermitilis MA-4680 1215826 NP_826399.1 CDS SAV_5222 NC_003155.4 6330754 6331950 D PF01145: SPFH domain / Band 7 family; hypothetical protein 6330754..6331950 Streptomyces avermitilis MA-4680 1215827 NP_826400.1 CDS chb NC_003155.4 6332060 6332716 D chitin binding protein 6332060..6332716 Streptomyces avermitilis MA-4680 1211226 NP_826401.1 CDS SAV_5224 NC_003155.4 6332821 6333291 D hypothetical protein 6332821..6333291 Streptomyces avermitilis MA-4680 1215828 NP_826402.1 CDS fadD11 NC_003155.4 6333369 6335009 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 6333369..6335009 Streptomyces avermitilis MA-4680 1211227 NP_826403.1 CDS SAV_5226 NC_003155.4 6335273 6336124 R IclR family transcriptional regulator complement(6335273..6336124) Streptomyces avermitilis MA-4680 1215829 NP_826404.1 CDS SAV_5227 NC_003155.4 6336208 6337023 R amino acid ABC transporter ATP-binding protein complement(6336208..6337023) Streptomyces avermitilis MA-4680 1215830 NP_826405.1 CDS SAV_5228 NC_003155.4 6337013 6337663 R amino acid ABC transporter permease complement(6337013..6337663) Streptomyces avermitilis MA-4680 1215831 NP_826406.1 CDS SAV_5229 NC_003155.4 6337660 6338409 R amino acid ABC transporter permease complement(6337660..6338409) Streptomyces avermitilis MA-4680 1215832 NP_826407.1 CDS SAV_5230 NC_003155.4 6338406 6339332 R ABC transporter substrate-binding protein complement(6338406..6339332) Streptomyces avermitilis MA-4680 1215833 NP_826408.1 CDS SAV_5231 NC_003155.4 6339462 6339950 D hypothetical protein 6339462..6339950 Streptomyces avermitilis MA-4680 1215834 NP_826409.1 CDS SAV_5232 NC_003155.4 6339980 6341422 R putative amidase complement(6339980..6341422) Streptomyces avermitilis MA-4680 1215835 NP_826410.1 CDS SAV_5233 NC_003155.4 6341451 6342410 R NAD-binding protein complement(6341451..6342410) Streptomyces avermitilis MA-4680 1215836 NP_826411.1 CDS SAV_5234 NC_003155.4 6342585 6343388 D PF01177: Asp/Glu/Hydantoin racemase; decarboxylase 6342585..6343388 Streptomyces avermitilis MA-4680 1215837 NP_826412.1 CDS SAV_5235 NC_003155.4 6343385 6344119 D PF01177: Asp/Glu/Hydantoin racemase; decarboxylase 6343385..6344119 Streptomyces avermitilis MA-4680 1215838 NP_826413.1 CDS SAV_5236 NC_003155.4 6344263 6345414 D PF00296: Luciferase-like monooxygenase; LuxAB-like protein (oxygenase) 6344263..6345414 Streptomyces avermitilis MA-4680 1215839 NP_826414.1 CDS SAV_5237 NC_003155.4 6345466 6347328 R PF00563: EAL domain; sensory box/GGDEF family protein complement(6345466..6347328) Streptomyces avermitilis MA-4680 1215840 NP_826415.1 CDS SAV_5238 NC_003155.4 6347684 6349207 D hypothetical protein 6347684..6349207 Streptomyces avermitilis MA-4680 1215841 NP_826416.1 CDS SAV_5239 NC_003155.4 6349376 6350023 R hypothetical protein complement(6349376..6350023) Streptomyces avermitilis MA-4680 1215842 NP_826417.1 CDS SAV_5240 NC_003155.4 6350223 6350588 R hypothetical protein complement(6350223..6350588) Streptomyces avermitilis MA-4680 1215843 NP_826418.1 CDS SAV_5241 NC_003155.4 6350999 6352318 R PF00270: DEAD/DEAH box helicase; hypothetical protein complement(6350999..6352318) Streptomyces avermitilis MA-4680 1215844 NP_826419.1 CDS SAV_5242 NC_003155.4 6352315 6353910 R hypothetical protein complement(6352315..6353910) Streptomyces avermitilis MA-4680 1215845 NP_826420.1 CDS SAV_5243 NC_003155.4 6353901 6354941 R protein complement(6353901..6354941) Streptomyces avermitilis MA-4680 1215846 NP_826421.1 CDS SAV_5244 NC_003155.4 6355048 6356004 R hypothetical protein complement(6355048..6356004) Streptomyces avermitilis MA-4680 1215847 NP_826422.1 CDS SAV_5245 NC_003155.4 6356198 6356815 D mutase 6356198..6356815 Streptomyces avermitilis MA-4680 1215848 NP_826423.1 CDS SAV_5246 NC_003155.4 6356869 6358461 R PF06036: Streptomyces protein of unknown function (DUF921); hypothetical protein complement(6356869..6358461) Streptomyces avermitilis MA-4680 1215849 NP_826424.1 CDS SAV_5247 NC_003155.4 6358763 6359197 D hypothetical protein 6358763..6359197 Streptomyces avermitilis MA-4680 1215850 NP_826425.1 CDS SAV_5248 NC_003155.4 6359325 6360218 D hypothetical protein 6359325..6360218 Streptomyces avermitilis MA-4680 1215851 NP_826426.1 CDS SAV_5249 NC_003155.4 6360258 6360788 R protein complement(6360258..6360788) Streptomyces avermitilis MA-4680 1215852 NP_826427.1 CDS SAV_5250 NC_003155.4 6360937 6361680 D two-component system response regulator 6360937..6361680 Streptomyces avermitilis MA-4680 1215853 NP_826428.1 CDS SAV_5251 NC_003155.4 6361677 6363050 D two-component system sensor kinase 6361677..6363050 Streptomyces avermitilis MA-4680 1215854 NP_826429.1 CDS SAV_5252 NC_003155.4 6363284 6364753 D PF00553: Cellulose binding domain; sugar hydrolase 6363284..6364753 Streptomyces avermitilis MA-4680 1215855 NP_826430.1 CDS bglC2 NC_003155.4 6364894 6366342 R beta-glucosidase complement(6364894..6366342) Streptomyces avermitilis MA-4680 1215856 NP_826431.1 CDS cebG NC_003155.4 6366512 6367435 R cellobiose ABC transporter permease complement(6366512..6367435) Streptomyces avermitilis MA-4680 1215857 NP_826432.1 CDS cebF NC_003155.4 6367448 6368464 R cellobiose ABC transporter permease complement(6367448..6368464) Streptomyces avermitilis MA-4680 1215858 NP_826433.1 CDS cebE NC_003155.4 6368470 6369831 R cellobiose ABC transporter substrate-binding protein complement(6368470..6369831) Streptomyces avermitilis MA-4680 1215859 NP_826434.1 CDS SAV_5257 NC_003155.4 6370230 6371285 D LacI family transcriptional regulator 6370230..6371285 Streptomyces avermitilis MA-4680 1215860 NP_826435.1 CDS SAV_5258 NC_003155.4 6371369 6371977 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(6371369..6371977) Streptomyces avermitilis MA-4680 1215861 NP_826436.1 CDS SAV_5259 NC_003155.4 6372118 6372600 R hypothetical protein complement(6372118..6372600) Streptomyces avermitilis MA-4680 1215862 NP_826437.1 CDS orn NC_003155.4 6372895 6373497 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(6372895..6373497) Streptomyces avermitilis MA-4680 1211231 NP_826438.1 CDS SAV_5261 NC_003155.4 6373649 6374929 R AraC family transcription regulator complement(6373649..6374929) Streptomyces avermitilis MA-4680 1215863 NP_826439.1 CDS SAV_5262 NC_003155.4 6375308 6375745 R PF07172: Glycine rich protein family; hypothetical protein complement(6375308..6375745) Streptomyces avermitilis MA-4680 1215864 NP_826440.1 CDS SAV_5263 NC_003155.4 6376089 6376616 D PF00582: Universal stress protein family; hypothetical protein 6376089..6376616 Streptomyces avermitilis MA-4680 1215865 NP_826441.1 CDS SAV_5264 NC_003155.4 6376767 6377333 D PF01184: GPR1/FUN34/yaaH family; hypothetical protein 6376767..6377333 Streptomyces avermitilis MA-4680 1215866 NP_826442.1 CDS glmS2 NC_003155.4 6377438 6379255 R L-glutamine-D-fructose-6-phosphate amidotransferase complement(6377438..6379255) Streptomyces avermitilis MA-4680 1211232 NP_826443.1 CDS SAV_5266 NC_003155.4 6379293 6379550 R hypothetical protein complement(6379293..6379550) Streptomyces avermitilis MA-4680 1215867 NP_826444.1 CDS ppe2 NC_003155.4 6379752 6381278 D phosphoesterase 6379752..6381278 Streptomyces avermitilis MA-4680 1211233 NP_826445.1 CDS nagZ4 NC_003155.4 6381542 6383131 D beta-N-acetylhexosaminidase 6381542..6383131 Streptomyces avermitilis MA-4680 1211234 NP_826446.1 CDS sidA NC_003155.4 6383181 6384953 R alcC, siderophore biosynthesis, PF04183: IucA / IucC family; siderophore biosynthetic enzyme complement(6383181..6384953) Streptomyces avermitilis MA-4680 1211235 NP_826447.1 CDS sidB NC_003155.4 6384950 6385501 R alcB, siderophore biosynthesis, PF00583: Acetyltransferase (GNAT) family; aceytltranferase complement(6384950..6385501) Streptomyces avermitilis MA-4680 1211236 NP_826448.1 CDS sidC NC_003155.4 6385498 6386769 R alcA, siderophore biosynthesis; monooxigenase complement(6385498..6386769) Streptomyces avermitilis MA-4680 1211237 NP_826449.1 CDS sidD NC_003155.4 6386774 6388291 R rhbB, siderophore biosynthesis, PF00282: Pyridoxal-dependent decarboxylase conserved domain; L-2,4-diaminobutyrate decarboxylase complement(6386774..6388291) Streptomyces avermitilis MA-4680 1211238 NP_826450.1 CDS sidE NC_003155.4 6388354 6389226 R siderophore biosynthesis, PF04954: Siderophore-interacting protein; siderophore-interacting protein complement(6388354..6389226) Streptomyces avermitilis MA-4680 1215868 NP_826451.1 CDS sidF NC_003155.4 6389302 6390351 R siderophore biosynthesis; ferrichrome ABC transporter substrate-binding protein complement(6389302..6390351) Streptomyces avermitilis MA-4680 1215869 NP_826452.1 CDS fadE4 NC_003155.4 6390485 6391645 R acdH, PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(6390485..6391645) Streptomyces avermitilis MA-4680 1211239 NP_826453.1 CDS hmgL NC_003155.4 6391651 6392598 R hydroxymethylglutaryl-CoA lyase complement(6391651..6392598) Streptomyces avermitilis MA-4680 1211240 NP_826454.1 CDS accA1 NC_003155.4 6392595 6394697 R acetyl/propionyl CoA carboxylase alpha subunit complement(6392595..6394697) Streptomyces avermitilis MA-4680 1211241 NP_826455.1 CDS accD1 NC_003155.4 6394706 6396337 R acetyl/propionyl CoA carboxylase, beta subunit complement(6394706..6396337) Streptomyces avermitilis MA-4680 1211242 NP_826456.1 CDS SAV_5279 NC_003155.4 6396435 6397025 D TetR family transcriptional regulator 6396435..6397025 Streptomyces avermitilis MA-4680 1215870 NP_826457.1 CDS fadE7 NC_003155.4 6397123 6398280 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 6397123..6398280 Streptomyces avermitilis MA-4680 1211243 NP_826458.1 CDS tesB2 NC_003155.4 6398315 6399187 D PF02551: Acyl-CoA thioesterase; acyl-CoA thioesterase 6398315..6399187 Streptomyces avermitilis MA-4680 1211244 NP_826459.1 CDS SAV_5282 NC_003155.4 6399273 6400061 R hypothetical protein complement(6399273..6400061) Streptomyces avermitilis MA-4680 1215871 NP_826460.1 CDS SAV_5283 NC_003155.4 6400144 6401757 R regulatory protein complement(6400144..6401757) Streptomyces avermitilis MA-4680 1215872 NP_826461.1 CDS SAV_5284 NC_003155.4 6401945 6403405 D PF00474: Sodium:solute symporter family; sodium:solute symporter 6401945..6403405 Streptomyces avermitilis MA-4680 1215873 NP_826462.1 CDS speB NC_003155.4 6403444 6404412 D agmatinase 6403444..6404412 Streptomyces avermitilis MA-4680 1211245 NP_826463.1 CDS ilvB4 NC_003155.4 6404409 6406094 D acetolactate synthase 6404409..6406094 Streptomyces avermitilis MA-4680 1211246 NP_826464.1 CDS SAV_5287 NC_003155.4 6406163 6407590 R PF01839: FG-GAP repeat; hypothetical protein complement(6406163..6407590) Streptomyces avermitilis MA-4680 1215874 NP_826465.1 CDS SAV_5288 NC_003155.4 6407814 6408467 R hypothetical protein complement(6407814..6408467) Streptomyces avermitilis MA-4680 1215875 NP_826466.1 CDS SAV_5289 NC_003155.4 6408531 6409337 R PF04231: Endonuclease I; ribonuclease complement(6408531..6409337) Streptomyces avermitilis MA-4680 1215876 NP_826467.1 CDS SAV_5290 NC_003155.4 6409562 6411889 R PF02366: Dolichyl-phosphate-mannose-protein mannosyltransferase; integral membrane protein complement(6409562..6411889) Streptomyces avermitilis MA-4680 1215877 NP_826468.1 CDS SAV_5291 NC_003155.4 6412403 6412882 D hypothetical protein 6412403..6412882 Streptomyces avermitilis MA-4680 1215878 NP_826469.1 CDS SAV_5292 NC_003155.4 6413260 6415170 D PF01079: Hint module; hypothetical protein 6413260..6415170 Streptomyces avermitilis MA-4680 1215879 NP_826470.1 CDS SAV_5293 NC_003155.4 6415575 6416147 D hypothetical protein 6415575..6416147 Streptomyces avermitilis MA-4680 1215880 NP_826471.1 CDS SAV_5294 NC_003155.4 6416192 6416413 R regulatory protein complement(6416192..6416413) Streptomyces avermitilis MA-4680 1215881 NP_826472.1 CDS SAV_5295 NC_003155.4 6416406 6417206 R DNA-binding protein complement(6416406..6417206) Streptomyces avermitilis MA-4680 1215882 NP_826473.1 CDS SAV_5296 NC_003155.4 6417274 6417711 D hypothetical protein 6417274..6417711 Streptomyces avermitilis MA-4680 1215883 NP_826474.1 CDS SAV_5297 NC_003155.4 6417708 6418046 D hypothetical protein 6417708..6418046 Streptomyces avermitilis MA-4680 1215884 NP_826475.1 CDS SAV_5298 NC_003155.4 6418264 6419196 D protein 6418264..6419196 Streptomyces avermitilis MA-4680 1215885 NP_826476.1 CDS SAV_5299 NC_003155.4 6419461 6423234 D ABC transporter ATP-binding protein 6419461..6423234 Streptomyces avermitilis MA-4680 1215886 NP_826477.1 CDS SAV_5300 NC_003155.4 6423971 6425419 D PF05576: PS-10 peptidase S37; tripeptidyl aminopeptidase 6423971..6425419 Streptomyces avermitilis MA-4680 1215887 NP_826478.1 CDS SAV_5301 NC_003155.4 6425826 6426458 R hypothetical protein complement(6425826..6426458) Streptomyces avermitilis MA-4680 1215888 NP_826479.1 CDS nagZ5 NC_003155.4 6426573 6428423 R beta-N-acetylhexosaminidase complement(6426573..6428423) Streptomyces avermitilis MA-4680 1211247 NP_826480.1 CDS SAV_5303 NC_003155.4 6428842 6429768 R LysR family transcriptional regulator complement(6428842..6429768) Streptomyces avermitilis MA-4680 1215889 NP_826481.1 CDS SAV_5304 NC_003155.4 6429856 6430776 D PF00892: Integral membrane protein DUF6; hypothetical protein 6429856..6430776 Streptomyces avermitilis MA-4680 1215890 NP_826482.1 CDS SAV_5305 NC_003155.4 6430773 6431282 D hypothetical protein 6430773..6431282 Streptomyces avermitilis MA-4680 1215891 NP_826483.1 CDS SAV_5306 NC_003155.4 6431284 6433035 R hypothetical protein complement(6431284..6433035) Streptomyces avermitilis MA-4680 1215892 NP_826484.1 CDS SAV_5307 NC_003155.4 6433101 6434729 R PF05419: GUN4-like; hypothetical protein complement(6433101..6434729) Streptomyces avermitilis MA-4680 1215893 NP_826485.1 CDS pkn25 NC_003155.4 6434726 6435712 R serine/threonine protein kinase complement(6434726..6435712) Streptomyces avermitilis MA-4680 1211248 NP_826486.1 CDS SAV_5309 NC_003155.4 6435765 6436322 R hypothetical protein complement(6435765..6436322) Streptomyces avermitilis MA-4680 1215894 NP_826487.1 CDS SAV_5310 NC_003155.4 6436457 6437257 R PF01261: AP endonuclease family 2; hypothetical protein complement(6436457..6437257) Streptomyces avermitilis MA-4680 1215895 NP_826488.1 CDS SAV_5311 NC_003155.4 6437291 6438223 R MarR family transcriptional regulator complement(6437291..6438223) Streptomyces avermitilis MA-4680 1215896 NP_826489.1 CDS SAV_5312 NC_003155.4 6438512 6439552 R LacI family transcriptional regulator complement(6438512..6439552) Streptomyces avermitilis MA-4680 1215897 NP_826490.1 CDS SAV_5313 NC_003155.4 6439787 6440938 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 6439787..6440938 Streptomyces avermitilis MA-4680 1215898 NP_826491.1 CDS SAV_5314 NC_003155.4 6440935 6442086 D PF06187: Protein of unknown function (DUF993); hypothetical protein 6440935..6442086 Streptomyces avermitilis MA-4680 1215899 NP_826492.1 CDS SAV_5315 NC_003155.4 6442083 6442916 D PF01261: AP endonuclease family 2; hypothetical protein 6442083..6442916 Streptomyces avermitilis MA-4680 1215900 NP_826493.1 CDS rbsD NC_003155.4 6443152 6443541 R cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase complement(6443152..6443541) Streptomyces avermitilis MA-4680 1211249 NP_826494.1 CDS rbsK NC_003155.4 6443538 6444437 R PF00294: pfkB family carbohydrate kinase; ribokinase complement(6443538..6444437) Streptomyces avermitilis MA-4680 1211250 NP_826495.1 CDS rbsC NC_003155.4 6444518 6446464 R D-ribose transport system; D-ribose ABC transporter permease complement(6444518..6446464) Streptomyces avermitilis MA-4680 1211251 NP_826496.1 CDS rbsA NC_003155.4 6446454 6448022 R D-ribose transport system; D-ribose ABC transporter ATP-binding protein complement(6446454..6448022) Streptomyces avermitilis MA-4680 1211252 NP_826497.1 CDS rbsR NC_003155.4 6448019 6449083 R transcriptional regulator mediating carbon catabolite repression; LacI family transcriptional regulator complement(6448019..6449083) Streptomyces avermitilis MA-4680 1211253 NP_826498.1 CDS SAV_5321 NC_003155.4 6449441 6449773 D hypothetical protein 6449441..6449773 Streptomyces avermitilis MA-4680 1215901 NP_826499.1 CDS SAV_5322 NC_003155.4 6449871 6450188 D hypothetical protein 6449871..6450188 Streptomyces avermitilis MA-4680 1215902 NP_826500.1 CDS SAV_5323 NC_003155.4 6450229 6450627 D hypothetical protein 6450229..6450627 Streptomyces avermitilis MA-4680 1215903 NP_826501.1 CDS SAV_5324 NC_003155.4 6450624 6453326 D hypothetical protein 6450624..6453326 Streptomyces avermitilis MA-4680 1215904 NP_826502.1 CDS SAV_5325 NC_003155.4 6453323 6454330 D hypothetical protein 6453323..6454330 Streptomyces avermitilis MA-4680 1215905 NP_826503.1 CDS SAV_5326 NC_003155.4 6454562 6454924 D hypothetical protein 6454562..6454924 Streptomyces avermitilis MA-4680 1215906 NP_826504.1 CDS SAV_5327 NC_003155.4 6454903 6455595 D hypothetical protein 6454903..6455595 Streptomyces avermitilis MA-4680 1215907 NP_826505.1 CDS SAV_5328 NC_003155.4 6455728 6456090 D hypothetical protein 6455728..6456090 Streptomyces avermitilis MA-4680 1215908 NP_826506.1 CDS recD NC_003155.4 6456160 6458436 D PF05127: Putative ATPase (DUF699); exodeoxyribonuclease V 6456160..6458436 Streptomyces avermitilis MA-4680 1211254 NP_826507.1 CDS gltA NC_003155.4 6458679 6459968 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 6458679..6459968 Streptomyces avermitilis MA-4680 1211255 NP_826508.1 CDS ctpA NC_003155.4 6460625 6462877 R PF00122: E1-E2 ATPase; cation-transporting P-type ATPase complement(6460625..6462877) Streptomyces avermitilis MA-4680 1211256 NP_826509.1 CDS SAV_5332 NC_003155.4 6462983 6463222 R copper chaperone complement(6462983..6463222) Streptomyces avermitilis MA-4680 1215909 NP_826510.1 CDS SAV_5333 NC_003155.4 6463533 6464231 R TetR family transcriptional regulator complement(6463533..6464231) Streptomyces avermitilis MA-4680 1215910 NP_826511.1 CDS SAV_5334 NC_003155.4 6464399 6466717 D PF03176: MMPL family; hypothetical protein 6464399..6466717 Streptomyces avermitilis MA-4680 1215911 NP_826512.1 CDS SAV_5335 NC_003155.4 6466793 6467836 D PF00107: Zinc-binding dehydrogenase; oxidoreductase 6466793..6467836 Streptomyces avermitilis MA-4680 1215912 NP_826513.1 CDS SAV_5336 NC_003155.4 6467912 6468190 R MarR family transcriptional regulator complement(6467912..6468190) Streptomyces avermitilis MA-4680 1215913 NP_826514.1 CDS iolE1 NC_003155.4 6468756 6469664 R inositol metaqbolism, PF06960: Myo-inositol catabolism protein N-terminus; IolE protein complement(6468756..6469664) Streptomyces avermitilis MA-4680 1215914 NP_826515.1 CDS iolC1 NC_003155.4 6469797 6470747 D inositol metabolism, PF00294: pfkB family carbohydrate kinase; IolC protein 6469797..6470747 Streptomyces avermitilis MA-4680 1215915 NP_826516.1 CDS SAV_5339 NC_003155.4 6470744 6471778 D PF04274: Tagatose 1,6-diphosphate aldolase, (LacD); hypothetical protein 6470744..6471778 Streptomyces avermitilis MA-4680 1215916 NP_826517.1 CDS iolB1 NC_003155.4 6471786 6472607 D inositol metabolism, PF06845: Myo-inositol catabolism protein IolB; IolB protein 6471786..6472607 Streptomyces avermitilis MA-4680 1211257 NP_826518.1 CDS iolD1 NC_003155.4 6472604 6474487 D inositol metabolism, PF00205: Thiamine pyrophosphate enzyme, central domain; IolD protein 6472604..6474487 Streptomyces avermitilis MA-4680 1211258 NP_826519.1 CDS iolA NC_003155.4 6474502 6476004 D methylmalonic acid semialdehyde dehydrogenase 6474502..6476004 Streptomyces avermitilis MA-4680 1211259 NP_826520.1 CDS SAV_5343 NC_003155.4 6476304 6477713 D PF00324: Amino acid permease; amino acid transporter 6476304..6477713 Streptomyces avermitilis MA-4680 1215917 NP_826521.1 CDS SAV_5344 NC_003155.4 6477929 6480523 D ABC transporter ATP-binding protein 6477929..6480523 Streptomyces avermitilis MA-4680 1215918 NP_826522.1 CDS SAV_5345 NC_003155.4 6480520 6481383 D ABC transporter permease 6480520..6481383 Streptomyces avermitilis MA-4680 1215919 NP_826523.1 CDS SAV_5346 NC_003155.4 6481983 6482243 D hypothetical protein 6481983..6482243 Streptomyces avermitilis MA-4680 1215920 NP_826524.1 CDS SAV_5347 NC_003155.4 6482542 6482802 D hypothetical protein 6482542..6482802 Streptomyces avermitilis MA-4680 1215921 NP_826525.1 CDS SAV_5348 NC_003155.4 6483136 6483474 D hypothetical protein 6483136..6483474 Streptomyces avermitilis MA-4680 1215922 NP_826526.1 CDS SAV_5349 NC_003155.4 6483734 6484015 D hypothetical protein 6483734..6484015 Streptomyces avermitilis MA-4680 1215923 NP_826527.1 CDS SAV_5350 NC_003155.4 6485437 6487158 D hypothetical protein 6485437..6487158 Streptomyces avermitilis MA-4680 1215924 NP_826528.1 CDS SAV_5351 NC_003155.4 6487510 6488730 D PF00746: Gram positive anchor; protein 6487510..6488730 Streptomyces avermitilis MA-4680 1215925 NP_826529.1 CDS SAV_5352 NC_003155.4 6488769 6489893 R hypothetical protein complement(6488769..6489893) Streptomyces avermitilis MA-4680 1215926 NP_826530.1 CDS SAV_5353 NC_003155.4 6489890 6490564 R PF02706: Chain length determinant protein; hypothetical protein complement(6489890..6490564) Streptomyces avermitilis MA-4680 1215927 NP_826531.1 CDS SAV_5354 NC_003155.4 6490564 6491739 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(6490564..6491739) Streptomyces avermitilis MA-4680 1215928 NP_826532.1 CDS SAV_5355 NC_003155.4 6491750 6492448 R PF01522: Polysaccharide deacetylase; polysaccharide deacetylase complement(6491750..6492448) Streptomyces avermitilis MA-4680 1215929 NP_826533.1 CDS SAV_5356 NC_003155.4 6492519 6494279 R PF03023: MviN-like protein; hypothetical protein complement(6492519..6494279) Streptomyces avermitilis MA-4680 1215930 NP_826534.1 CDS SAV_5357 NC_003155.4 6494276 6495631 R PF04932: O-Antigen Polymerase; hypothetical protein complement(6494276..6495631) Streptomyces avermitilis MA-4680 1215931 NP_826535.1 CDS SAV_5358 NC_003155.4 6495638 6497113 R PF02397: Bacterial sugar transferase; sugar transferase complement(6495638..6497113) Streptomyces avermitilis MA-4680 1215932 NP_826536.1 CDS SAV_5359 NC_003155.4 6497110 6498351 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(6497110..6498351) Streptomyces avermitilis MA-4680 1215933 NP_826537.1 CDS SAV_5360 NC_003155.4 6499049 6499312 D protein 6499049..6499312 Streptomyces avermitilis MA-4680 1215934 NP_826538.1 CDS melC2-2 NC_003155.4 6500109 6500495 D second mel operon; tyrosinase co-factor protein 6500109..6500495 Streptomyces avermitilis MA-4680 1211260 NP_826539.1 CDS melC1-2 NC_003155.4 6500482 6501345 D second mel operon, not form melanin; tyrosinase 6500482..6501345 Streptomyces avermitilis MA-4680 1211261 NP_826540.1 CDS SAV_5363 NC_003155.4 6501856 6503502 D ATP-binding protein 6501856..6503502 Streptomyces avermitilis MA-4680 1215935 NP_826541.1 CDS SAV_5364 NC_003155.4 6503805 6505673 D ATP-binding protein 6503805..6505673 Streptomyces avermitilis MA-4680 1215936 NP_826542.1 CDS SAV_5365 NC_003155.4 6505871 6506347 D single-strand DNA-binding protein 6505871..6506347 Streptomyces avermitilis MA-4680 1215937 NP_826543.1 CDS SAV_5366 NC_003155.4 6506611 6508026 D PF05506: Domain of unknown function (DUF756); hypothetical protein 6506611..6508026 Streptomyces avermitilis MA-4680 1215938 NP_826544.1 CDS SAV_5367 NC_003155.4 6508321 6509964 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 6508321..6509964 Streptomyces avermitilis MA-4680 1215939 NP_826545.1 CDS SAV_5368 NC_003155.4 6509967 6510377 D PF03061: Thioesterase superfamily; hypothetical protein 6509967..6510377 Streptomyces avermitilis MA-4680 1215940 NP_826546.1 CDS SAV_5369 NC_003155.4 6510374 6511069 D hypothetical protein 6510374..6511069 Streptomyces avermitilis MA-4680 1215941 NP_826547.1 CDS glbO NC_003155.4 6511098 6511502 R PF01152: Bacterial-like globin; globin-like protein complement(6511098..6511502) Streptomyces avermitilis MA-4680 1215942 NP_826548.1 CDS SAV_5371 NC_003155.4 6511654 6512634 D O-methyltransferase 6511654..6512634 Streptomyces avermitilis MA-4680 1215943 NP_826549.1 CDS SAV_5372 NC_003155.4 6512668 6514113 R PF00498: FHA domain; hypothetical protein complement(6512668..6514113) Streptomyces avermitilis MA-4680 1215944 NP_826550.1 CDS SAV_5373 NC_003155.4 6514219 6515595 R PF00092: von Willebrand factor type A domain; hypothetical protein complement(6514219..6515595) Streptomyces avermitilis MA-4680 1215945 NP_826551.1 CDS prpB10 NC_003155.4 6515722 6517065 R PF00481: Protein phosphatase 2C; magnesium or manganese-dependent protein phosphatase complement(6515722..6517065) Streptomyces avermitilis MA-4680 1215946 NP_826552.1 CDS pkn26 NC_003155.4 6517066 6519570 R serine/threonine protein kinase complement(6517066..6519570) Streptomyces avermitilis MA-4680 1211263 NP_826553.1 CDS SAV_5376 NC_003155.4 6519590 6520915 R hypothetical protein complement(6519590..6520915) Streptomyces avermitilis MA-4680 1215947 NP_826554.1 CDS SAV_5377 NC_003155.4 6521003 6522010 R amino acid ABC transporter substrate-binding protein complement(6521003..6522010) Streptomyces avermitilis MA-4680 1215948 NP_826555.1 CDS SAV_5378 NC_003155.4 6522025 6523488 R protein complement(6522025..6523488) Streptomyces avermitilis MA-4680 1215949 NP_826556.1 CDS SAV_5379 NC_003155.4 6523797 6524753 R kinase complement(6523797..6524753) Streptomyces avermitilis MA-4680 1215950 NP_826557.1 CDS bglA2 NC_003155.4 6524786 6526051 R 6-phospho-beta-glucosidase complement(6524786..6526051) Streptomyces avermitilis MA-4680 1215951 NP_826558.1 CDS SAV_5381 NC_003155.4 6526055 6526948 R sugar ABC transporter permease complement(6526055..6526948) Streptomyces avermitilis MA-4680 1215952 NP_826559.1 CDS SAV_5382 NC_003155.4 6526951 6527892 R sugar ABC transporter permease complement(6526951..6527892) Streptomyces avermitilis MA-4680 1215953 NP_826560.1 CDS SAV_5383 NC_003155.4 6527895 6529232 R sugar ABC transporter substrate-binding protein complement(6527895..6529232) Streptomyces avermitilis MA-4680 1215954 NP_826561.1 CDS SAV_5384 NC_003155.4 6529378 6530589 R transcriptional regulator complement(6529378..6530589) Streptomyces avermitilis MA-4680 1215955 NP_826562.1 CDS SAV_5385 NC_003155.4 6531060 6532160 R PF00924: Mechanosensitive ion channel; hypothetical protein complement(6531060..6532160) Streptomyces avermitilis MA-4680 1215956 NP_826563.1 CDS SAV_5386 NC_003155.4 6532474 6533010 D endonuclease 6532474..6533010 Streptomyces avermitilis MA-4680 1215957 NP_826564.1 CDS SAV_5387 NC_003155.4 6533165 6534508 R PF02687: Predicted permease; hypothetical protein complement(6533165..6534508) Streptomyces avermitilis MA-4680 1215958 NP_826565.1 CDS SAV_5388 NC_003155.4 6534505 6535218 R ABC transporter ATP-binding protein complement(6534505..6535218) Streptomyces avermitilis MA-4680 1215959 NP_826566.1 CDS SAV_5389 NC_003155.4 6535215 6535748 R PadR-family transcriptional regulator complement(6535215..6535748) Streptomyces avermitilis MA-4680 1215960 NP_826567.1 CDS SAV_5390 NC_003155.4 6535919 6536170 D hypothetical protein 6535919..6536170 Streptomyces avermitilis MA-4680 1215961 NP_826568.1 CDS malQ NC_003155.4 6536171 6538393 D 4-alpha-glucanotransferase 6536171..6538393 Streptomyces avermitilis MA-4680 1211264 NP_826569.1 CDS SAV_5392 NC_003155.4 6538495 6538734 D hypothetical protein 6538495..6538734 Streptomyces avermitilis MA-4680 1215962 NP_826570.1 CDS SAV_5393 NC_003155.4 6538935 6539465 R MarR family transcriptional regulator complement(6538935..6539465) Streptomyces avermitilis MA-4680 1215963 NP_826571.1 CDS SAV_5394 NC_003155.4 6539576 6540685 D PF00892: Integral membrane protein DUF6; hypothetical protein 6539576..6540685 Streptomyces avermitilis MA-4680 1215964 NP_826572.1 CDS pepN1 NC_003155.4 6540741 6543314 R PF01433: Peptidase family M1; aminopeptidase N complement(6540741..6543314) Streptomyces avermitilis MA-4680 1211265 NP_826573.1 CDS SAV_5396 NC_003155.4 6543427 6543948 D PF06718: Protein of unknown function (DUF1203); hypothetical protein 6543427..6543948 Streptomyces avermitilis MA-4680 1215965 NP_826574.1 CDS asd2 NC_003155.4 6543990 6545006 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(6543990..6545006) Streptomyces avermitilis MA-4680 1211266 NP_826575.1 CDS sig46 NC_003155.4 6545341 6545880 D ECF subfamily RNA polymerase sigma factor 6545341..6545880 Streptomyces avermitilis MA-4680 1211267 NP_826576.1 CDS SAV_5399 NC_003155.4 6545882 6546634 D hypothetical protein 6545882..6546634 Streptomyces avermitilis MA-4680 1215966 NP_826577.1 CDS SAV_5400 NC_003155.4 6546704 6550009 R PF00082: Subtilase family; serine protease complement(6546704..6550009) Streptomyces avermitilis MA-4680 1215967 NP_826578.1 CDS SAV_5401 NC_003155.4 6550265 6550801 R PF07336: Protein of unknown function (DUF1470); hypothetical protein complement(6550265..6550801) Streptomyces avermitilis MA-4680 1215968 NP_826579.1 CDS gloA NC_003155.4 6550921 6551373 D lactoylglutathione lyase 6550921..6551373 Streptomyces avermitilis MA-4680 1215969 NP_826580.1 CDS SAV_5403 NC_003155.4 6551389 6552270 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 6551389..6552270 Streptomyces avermitilis MA-4680 1215970 NP_826581.1 CDS SAV_5404 NC_003155.4 6552280 6552738 D PF00293: NUDIX domain; hypothetical protein 6552280..6552738 Streptomyces avermitilis MA-4680 1215971 NP_826582.1 CDS SAV_5405 NC_003155.4 6552981 6554771 D PF00149: Calcineurin-like phosphoesterase; hypothetical protein 6552981..6554771 Streptomyces avermitilis MA-4680 1215972 NP_826583.1 CDS SAV_5406 NC_003155.4 6554938 6556161 R PF01833: IPT/TIG domain; hypothetical protein complement(6554938..6556161) Streptomyces avermitilis MA-4680 1215973 NP_826584.1 CDS SAV_5407 NC_003155.4 6556529 6556738 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6556529..6556738) Streptomyces avermitilis MA-4680 1215974 NP_826585.1 CDS SAV_5408 NC_003155.4 6556743 6557630 R DNA-binding protein complement(6556743..6557630) Streptomyces avermitilis MA-4680 1215975 NP_826586.1 CDS SAV_5409 NC_003155.4 6557797 6558324 D regulatory protein 6557797..6558324 Streptomyces avermitilis MA-4680 1215976 NP_826587.1 CDS SAV_5410 NC_003155.4 6558356 6559105 R hypothetical protein complement(6558356..6559105) Streptomyces avermitilis MA-4680 1215977 NP_826588.1 CDS pepN2 NC_003155.4 6559622 6562129 R PF01433: Peptidase family M1; aminopeptidase N complement(6559622..6562129) Streptomyces avermitilis MA-4680 1215978 NP_826589.1 CDS SAV_5412 NC_003155.4 6562354 6562992 D PF01323: DSBA-like thioredoxin domain; hypothetical protein 6562354..6562992 Streptomyces avermitilis MA-4680 1215979 NP_826590.1 CDS sodF NC_003155.4 6563423 6564064 R Fe-containing superoxide dismutase; superoxide dismutase complement(6563423..6564064) Streptomyces avermitilis MA-4680 1211268 NP_826591.1 CDS SAV_5414 NC_003155.4 6564205 6565593 R amino acid permease complement(6564205..6565593) Streptomyces avermitilis MA-4680 1215980 NP_826592.1 CDS SAV_5415 NC_003155.4 6565752 6566651 R PF02668: Taurine catabolism dioxygenase TauD, TfdA family; taurine catabolism dioxygenase complement(6565752..6566651) Streptomyces avermitilis MA-4680 1215981 NP_826593.1 CDS SAV_5416 NC_003155.4 6566666 6568027 R FMNH2-utilizing oxygenase complement(6566666..6568027) Streptomyces avermitilis MA-4680 1215982 NP_826594.1 CDS SAV_5417 NC_003155.4 6568024 6568776 R ABC transporter ATP-binding protein complement(6568024..6568776) Streptomyces avermitilis MA-4680 1215983 NP_826595.1 CDS SAV_5418 NC_003155.4 6568752 6569624 R ABC transporter permease complement(6568752..6569624) Streptomyces avermitilis MA-4680 1215984 NP_826596.1 CDS SAV_5419 NC_003155.4 6569630 6570703 R PF00497: Bacterial extracellular solute-binding proteins, family 3; hypothetical protein complement(6569630..6570703) Streptomyces avermitilis MA-4680 1215985 NP_826597.1 CDS SAV_5420 NC_003155.4 6571037 6572269 R transcriptional regulator complement(6571037..6572269) Streptomyces avermitilis MA-4680 1215986 NP_826598.1 CDS bioY NC_003155.4 6572704 6573285 D biotin synthase 6572704..6573285 Streptomyces avermitilis MA-4680 1211269 NP_826599.1 CDS SAV_5422 NC_003155.4 6573275 6574636 R FAD-dependent oxygenase complement(6573275..6574636) Streptomyces avermitilis MA-4680 1215987 NP_826600.1 CDS SAV_5423 NC_003155.4 6574704 6575474 R hypothetical protein complement(6574704..6575474) Streptomyces avermitilis MA-4680 1215988 NP_826601.1 CDS pkn27 NC_003155.4 6575595 6578006 D serine/threonine protein kinase 6575595..6578006 Streptomyces avermitilis MA-4680 1211270 NP_826602.1 CDS gabP NC_003155.4 6578092 6579576 R gamma-aminobutyrate permease complement(6578092..6579576) Streptomyces avermitilis MA-4680 1211271 NP_826603.1 CDS rpiB2 NC_003155.4 6579813 6580292 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 6579813..6580292 Streptomyces avermitilis MA-4680 1211272 NP_826604.1 CDS nei2 NC_003155.4 6580410 6581219 D involved in DNA repair; nick DNA at apurinic/apyrimidinic sites; endonuclease VIII and DNA N-glycosylase with an AP lyase activity 6580410..6581219 Streptomyces avermitilis MA-4680 1215989 NP_826605.1 CDS SAV_5428 NC_003155.4 6581347 6582576 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(6581347..6582576) Streptomyces avermitilis MA-4680 1215990 NP_826606.1 CDS prpB11 NC_003155.4 6582735 6583910 D membrane protein; magnesium or manganese-dependent protein phosphatase 6582735..6583910 Streptomyces avermitilis MA-4680 1215991 NP_826607.1 CDS SAV_5430 NC_003155.4 6584175 6585122 D ABC transporter ATP-binding protein 6584175..6585122 Streptomyces avermitilis MA-4680 1215992 NP_826608.1 CDS SAV_5431 NC_003155.4 6585128 6587572 D hypothetical protein 6585128..6587572 Streptomyces avermitilis MA-4680 1215993 NP_826609.1 CDS SAV_5432 NC_003155.4 6587774 6588106 D hypothetical protein 6587774..6588106 Streptomyces avermitilis MA-4680 1215994 NP_826610.1 CDS SAV_5433 NC_003155.4 6588160 6588474 D hypothetical protein 6588160..6588474 Streptomyces avermitilis MA-4680 1215995 NP_826611.1 CDS SAV_5434 NC_003155.4 6588533 6588928 D hypothetical protein 6588533..6588928 Streptomyces avermitilis MA-4680 1215996 NP_826612.1 CDS SAV_5435 NC_003155.4 6588925 6591399 D PF03496: Clostridial binary toxin A; hypothetical protein 6588925..6591399 Streptomyces avermitilis MA-4680 1215997 NP_826613.1 CDS SAV_5436 NC_003155.4 6591450 6591863 D hypothetical protein 6591450..6591863 Streptomyces avermitilis MA-4680 1215998 NP_826614.1 CDS SAV_5437 NC_003155.4 6591994 6592602 D hypothetical protein 6591994..6592602 Streptomyces avermitilis MA-4680 1215999 NP_826615.1 CDS SAV_5438 NC_003155.4 6592636 6593160 D PF01966: HD domain; hypothetical protein 6592636..6593160 Streptomyces avermitilis MA-4680 1216000 NP_826616.1 CDS SAV_5439 NC_003155.4 6593234 6593497 R hypothetical protein complement(6593234..6593497) Streptomyces avermitilis MA-4680 1216001 NP_826617.1 CDS SAV_5440 NC_003155.4 6593623 6594978 D PF04600: Protein of unknown function (DUF571); hypothetical protein 6593623..6594978 Streptomyces avermitilis MA-4680 1216002 NP_826618.1 CDS SAV_5441 NC_003155.4 6595249 6596349 D PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; hypothetical protein 6595249..6596349 Streptomyces avermitilis MA-4680 1216003 NP_826619.1 CDS SAV_5442 NC_003155.4 6596371 6600345 D FtsK/SpoIIIE family protein 6596371..6600345 Streptomyces avermitilis MA-4680 1216004 NP_826620.1 CDS SAV_5443 NC_003155.4 6600481 6601911 D hypothetical protein 6600481..6601911 Streptomyces avermitilis MA-4680 1216005 NP_826621.1 CDS SAV_5444 NC_003155.4 6602030 6603157 R PF01757: acyltransferase family; hypothetical protein complement(6602030..6603157) Streptomyces avermitilis MA-4680 1216006 NP_826622.1 CDS SAV_5445 NC_003155.4 6603863 6604057 D hypothetical protein 6603863..6604057 Streptomyces avermitilis MA-4680 1216007 NP_826623.1 CDS tig NC_003155.4 6604924 6606315 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 6604924..6606315 Streptomyces avermitilis MA-4680 1211275 NP_826624.1 CDS clpP NC_003155.4 6607644 6608303 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 6607644..6608303 Streptomyces avermitilis MA-4680 1211276 NP_826625.1 CDS clpP2 NC_003155.4 6608414 6609094 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 6608414..6609094 Streptomyces avermitilis MA-4680 1211277 NP_826626.1 CDS clpX NC_003155.4 6609255 6610541 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 6609255..6610541 Streptomyces avermitilis MA-4680 1211278 NP_826627.1 CDS SAV_5450 NC_003155.4 6610652 6611620 R hypothetical protein complement(6610652..6611620) Streptomyces avermitilis MA-4680 1216008 NP_826628.1 CDS valS NC_003155.4 6611757 6614381 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 6611757..6614381 Streptomyces avermitilis MA-4680 1211279 NP_826629.1 CDS fpgS NC_003155.4 6614987 6616348 D folylpolyglutamate synthase 6614987..6616348 Streptomyces avermitilis MA-4680 1211280 NP_826630.1 CDS SAV_5453 NC_003155.4 6616354 6616722 D hypothetical protein 6616354..6616722 Streptomyces avermitilis MA-4680 1216009 NP_826631.1 CDS ndk NC_003155.4 6616789 6617202 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 6616789..6617202 Streptomyces avermitilis MA-4680 1211281 NP_826632.1 CDS mreB1 NC_003155.4 6617490 6618521 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 6617490..6618521 Streptomyces avermitilis MA-4680 1211282 NP_826633.1 CDS mreC NC_003155.4 6618682 6619626 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 6618682..6619626 Streptomyces avermitilis MA-4680 1211283 NP_826634.1 CDS mreD NC_003155.4 6619640 6620311 D PF04093: rod shape-determining protein MreD; rod shape-determining protein 6619640..6620311 Streptomyces avermitilis MA-4680 1211284 NP_826635.1 CDS pbp10 NC_003155.4 6620398 6622647 D PF00905: Penicillin binding protein transpeptidase domain; penicillin-binding protein 6620398..6622647 Streptomyces avermitilis MA-4680 1211285 NP_826636.1 CDS ftsW2 NC_003155.4 6622682 6623878 D PF01098: Cell cycle protein; cell division membrane protein 6622682..6623878 Streptomyces avermitilis MA-4680 1211286 NP_826637.1 CDS SAV_5460 NC_003155.4 6624084 6625607 D hypothetical protein 6624084..6625607 Streptomyces avermitilis MA-4680 1216010 NP_826638.1 CDS SAV_5461 NC_003155.4 6625678 6627636 D PF04055: radical SAM superfamily; hypothetical protein 6625678..6627636 Streptomyces avermitilis MA-4680 1216011 NP_826639.1 CDS SAV_5462 NC_003155.4 6627793 6629124 R hypothetical protein complement(6627793..6629124) Streptomyces avermitilis MA-4680 1216012 NP_826640.1 CDS SAV_5463 NC_003155.4 6629472 6630719 D integral membrane protein 6629472..6630719 Streptomyces avermitilis MA-4680 1216013 NP_826641.1 CDS SAV_5464 NC_003155.4 6630766 6631560 D hypothetical protein 6630766..6631560 Streptomyces avermitilis MA-4680 1216014 NP_826642.1 CDS SAV_5465 NC_003155.4 6631806 6635969 D PF00575: S1 RNA binding domain; hypothetical protein 6631806..6635969 Streptomyces avermitilis MA-4680 1216015 NP_826643.1 CDS SAV_5466 NC_003155.4 6636201 6637550 D hypothetical protein 6636201..6637550 Streptomyces avermitilis MA-4680 1216016 NP_826644.1 CDS rplU NC_003155.4 6637749 6638069 D 50S ribosomal protein L21 6637749..6638069 Streptomyces avermitilis MA-4680 1211287 NP_826645.1 CDS rpmA NC_003155.4 6638084 6638338 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 6638084..6638338 Streptomyces avermitilis MA-4680 1211288 NP_826646.1 CDS obgE NC_003155.4 6638508 6639947 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 6638508..6639947 Streptomyces avermitilis MA-4680 1211289 NP_826647.1 CDS SAV_5470 NC_003155.4 6640249 6642423 R hypothetical protein complement(6640249..6642423) Streptomyces avermitilis MA-4680 1216017 NP_826648.1 CDS proB NC_003155.4 6642604 6643731 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 6642604..6643731 Streptomyces avermitilis MA-4680 1211290 NP_826649.1 CDS SAV_5472 NC_003155.4 6643870 6644415 D hypothetical protein 6643870..6644415 Streptomyces avermitilis MA-4680 1216018 NP_826650.1 CDS proA NC_003155.4 6644624 6645910 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 6644624..6645910 Streptomyces avermitilis MA-4680 1211291 NP_826651.1 CDS SAV_5474 NC_003155.4 6645936 6646688 D hypothetical protein 6645936..6646688 Streptomyces avermitilis MA-4680 1216019 NP_826652.1 CDS SAV_5475 NC_003155.4 6646898 6647965 D PF00866: Ring hydroxylating beta subunit; hypothetical protein 6646898..6647965 Streptomyces avermitilis MA-4680 1216020 NP_826653.1 CDS SAV_5476 NC_003155.4 6648111 6649241 R PF01435: Peptidase family M48; hypothetical protein complement(6648111..6649241) Streptomyces avermitilis MA-4680 1216021 NP_826654.1 CDS SAV_5477 NC_003155.4 6649647 6649811 D hypothetical protein 6649647..6649811 Streptomyces avermitilis MA-4680 1216022 NP_826655.1 CDS nadD NC_003155.4 6649972 6650646 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 6649972..6650646 Streptomyces avermitilis MA-4680 1211292 NP_826656.1 CDS SAV_5479 NC_003155.4 6650663 6652465 D PF03816: Cell envelope-related transcriptional attenuator domain; hypothetical protein 6650663..6652465 Streptomyces avermitilis MA-4680 1216023 NP_826657.1 CDS SAV_5480 NC_003155.4 6652631 6653077 D PF02410: Domain of unknown function DUF143; hypothetical protein 6652631..6653077 Streptomyces avermitilis MA-4680 1216024 NP_826658.1 CDS gpm2 NC_003155.4 6653074 6653748 D phosphoglycerate mutase 6653074..6653748 Streptomyces avermitilis MA-4680 1211293 NP_826659.1 CDS SAV_5482 NC_003155.4 6654016 6654909 R DNA-binding protein complement(6654016..6654909) Streptomyces avermitilis MA-4680 1216025 NP_826660.1 CDS SAV_5483 NC_003155.4 6655058 6656494 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 6655058..6656494 Streptomyces avermitilis MA-4680 1216026 NP_826661.1 CDS SAV_5484 NC_003155.4 6656741 6656974 D hypothetical protein 6656741..6656974 Streptomyces avermitilis MA-4680 1216027 NP_826662.1 CDS SAV_5485 NC_003155.4 6656953 6658167 R hypothetical protein complement(6656953..6658167) Streptomyces avermitilis MA-4680 1216028 NP_826663.1 CDS SAV_5486 NC_003155.4 6658504 6660078 R PF01512: Respiratory-chain NADH dehydrogenase 51 Kd subunit; oxidoreductase complement(6658504..6660078) Streptomyces avermitilis MA-4680 1216029 NP_826664.1 CDS SAV_5487 NC_003155.4 6660114 6661424 R integral membrane protein complement(6660114..6661424) Streptomyces avermitilis MA-4680 1216030 NP_826665.1 CDS leuS NC_003155.4 6661895 6664783 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 6661895..6664783 Streptomyces avermitilis MA-4680 1211296 NP_826666.1 CDS SAV_5489 NC_003155.4 6664923 6665660 D protein 6664923..6665660 Streptomyces avermitilis MA-4680 1216031 NP_826667.1 CDS SAV_5490 NC_003155.4 6665733 6666578 D PF02645: Uncharacterized protein, DegV family COG1307; hypothetical protein 6665733..6666578 Streptomyces avermitilis MA-4680 1216032 NP_826668.1 CDS SAV_5491 NC_003155.4 6666768 6667931 D DNA-binding protein 6666768..6667931 Streptomyces avermitilis MA-4680 1216033 NP_826669.1 CDS SAV_5492 NC_003155.4 6667928 6670450 D PF03772: Competence protein; hypothetical protein 6667928..6670450 Streptomyces avermitilis MA-4680 1216034 NP_826670.1 CDS SAV_5493 NC_003155.4 6670511 6670789 D probably phage genome; hypothetical protein 6670511..6670789 Streptomyces avermitilis MA-4680 1216035 NP_826671.1 CDS SAV_5494 NC_003155.4 6671196 6671525 D probably phage genome; hypothetical protein 6671196..6671525 Streptomyces avermitilis MA-4680 1216036 NP_826672.1 CDS SAV_5495 NC_003155.4 6671598 6671918 R probably phage genome; hypothetical protein complement(6671598..6671918) Streptomyces avermitilis MA-4680 1216037 NP_826673.1 CDS SAV_5496 NC_003155.4 6672034 6672387 R probably phage genome; hypothetical protein complement(6672034..6672387) Streptomyces avermitilis MA-4680 1216038 NP_826674.1 CDS SAV_5497 NC_003155.4 6672529 6673287 D probably phage genome; GntR family transcriptional regulator 6672529..6673287 Streptomyces avermitilis MA-4680 1216039 NP_826675.1 CDS SAV_5498 NC_003155.4 6673473 6674246 R probably phage genome, similar to phage structural protein; N-acetylmuramoyl-L-alanine amidase precursor complement(6673473..6674246) Streptomyces avermitilis MA-4680 1216040 NP_826676.1 CDS SAV_5499 NC_003155.4 6674323 6674634 R probably phage genome; hypothetical protein complement(6674323..6674634) Streptomyces avermitilis MA-4680 1216041 NP_826677.1 CDS SAV_5500 NC_003155.4 6674649 6674873 R probably phage genome; hypothetical protein complement(6674649..6674873) Streptomyces avermitilis MA-4680 1216042 NP_826678.1 CDS SAV_5501 NC_003155.4 6674875 6675222 R probably phage genome; hypothetical protein complement(6674875..6675222) Streptomyces avermitilis MA-4680 1216043 NP_826679.1 CDS SAV_5502 NC_003155.4 6675313 6676260 R probably phage genome; hypothetical protein complement(6675313..6676260) Streptomyces avermitilis MA-4680 1216044 NP_826680.1 CDS SAV_5503 NC_003155.4 6676364 6676564 R probably phage genome; hypothetical protein complement(6676364..6676564) Streptomyces avermitilis MA-4680 1216045 NP_826681.1 CDS SAV_5504 NC_003155.4 6676585 6678273 R probably phage genome; hypothetical protein complement(6676585..6678273) Streptomyces avermitilis MA-4680 1216046 NP_826682.1 CDS SAV_5505 NC_003155.4 6678303 6679331 R probably phage genome, similar to phage structure protein; hypothetical protein complement(6678303..6679331) Streptomyces avermitilis MA-4680 1216047 NP_826683.1 CDS SAV_5506 NC_003155.4 6679345 6680535 R probably phage genome; hypothetical protein complement(6679345..6680535) Streptomyces avermitilis MA-4680 1216048 NP_826684.1 CDS SAV_5507 NC_003155.4 6680539 6681474 R probably phage genome; hypothetical protein complement(6680539..6681474) Streptomyces avermitilis MA-4680 1216049 NP_826685.1 CDS SAV_5508 NC_003155.4 6681496 6684924 R probably phage genome, similar to phage tail protein; phage minor tail protein complement(6681496..6684924) Streptomyces avermitilis MA-4680 1216050 NP_826686.1 CDS SAV_5509 NC_003155.4 6684968 6685366 R probably phage genome; hypothetical protein complement(6684968..6685366) Streptomyces avermitilis MA-4680 1216051 NP_826687.1 CDS SAV_5510 NC_003155.4 6685465 6685797 R probably phage genome; hypothetical protein complement(6685465..6685797) Streptomyces avermitilis MA-4680 1216052 NP_826688.1 CDS SAV_5511 NC_003155.4 6685951 6686568 R probably phage genome, similar to phage structure protein; phage major tail protein complement(6685951..6686568) Streptomyces avermitilis MA-4680 1216053 NP_826689.1 CDS SAV_5512 NC_003155.4 6686629 6687072 R probably phage genome; hypothetical protein complement(6686629..6687072) Streptomyces avermitilis MA-4680 1216054 NP_826690.1 CDS SAV_5513 NC_003155.4 6687091 6687330 R probably phage genome; hypothetical protein complement(6687091..6687330) Streptomyces avermitilis MA-4680 1216055 NP_826691.1 CDS SAV_5514 NC_003155.4 6687334 6687618 R probably phage genome; hypothetical protein complement(6687334..6687618) Streptomyces avermitilis MA-4680 1216056 NP_826692.1 CDS SAV_5515 NC_003155.4 6687618 6687959 R probably phage genome; hypothetical protein complement(6687618..6687959) Streptomyces avermitilis MA-4680 1216057 NP_826693.1 CDS SAV_5516 NC_003155.4 6687963 6688358 R probably phage genome; hypothetical protein complement(6687963..6688358) Streptomyces avermitilis MA-4680 1216058 NP_826694.1 CDS SAV_5517 NC_003155.4 6688378 6688713 R probably phage genome; hypothetical protein complement(6688378..6688713) Streptomyces avermitilis MA-4680 1216059 NP_826695.1 CDS SAV_5518 NC_003155.4 6688744 6690066 R probably phage genome; hypothetical protein complement(6688744..6690066) Streptomyces avermitilis MA-4680 1216060 NP_826696.1 CDS SAV_5519 NC_003155.4 6690082 6690711 R probably phage genome, PF06810: Phage minor structural protein GP20; phage minor structural protein complement(6690082..6690711) Streptomyces avermitilis MA-4680 1216061 NP_826697.1 CDS SAV_5520 NC_003155.4 6690753 6692330 R probably phage genome, PF05126: Phage minor capsid protein; phage minor capsid protein complement(6690753..6692330) Streptomyces avermitilis MA-4680 1216062 NP_826698.1 CDS SAV_5521 NC_003155.4 6692327 6693625 R probably phage genome, PF03237: Protein of unknown function DUF264; phage-related terminase large subunit complement(6692327..6693625) Streptomyces avermitilis MA-4680 1216063 NP_826699.1 CDS SAV_5522 NC_003155.4 6693629 6694117 R probably phage genome, PF00196: Bacterial regulatory proteins, luxR family; hypothetical protein complement(6693629..6694117) Streptomyces avermitilis MA-4680 1216064 NP_826700.1 CDS SAV_5523 NC_003155.4 6694605 6694850 R probably phage genome; hypothetical protein complement(6694605..6694850) Streptomyces avermitilis MA-4680 1216065 NP_826701.1 CDS SAV_5524 NC_003155.4 6695024 6695500 D probably phage genome; hypothetical protein 6695024..6695500 Streptomyces avermitilis MA-4680 1216066 NP_826702.1 CDS SAV_5525 NC_003155.4 6695516 6695725 R probably phage genome, PF00376: MerR family regulatory protein; MerR family transcriptional regulator complement(6695516..6695725) Streptomyces avermitilis MA-4680 1216067 NP_826703.1 CDS SAV_5526 NC_003155.4 6695861 6696484 R probably phage genome, PF03536: Salmonella virulence-associated 28kDa protein; hypothetical protein complement(6695861..6696484) Streptomyces avermitilis MA-4680 1216068 NP_826704.1 CDS SAV_5527 NC_003155.4 6696583 6697143 R probably phage genome; hypothetical protein complement(6696583..6697143) Streptomyces avermitilis MA-4680 1216069 NP_826705.1 CDS SAV_5528 NC_003155.4 6697257 6697772 R probably phage genome; hypothetical protein complement(6697257..6697772) Streptomyces avermitilis MA-4680 1216070 NP_826706.1 CDS SAV_5529 NC_003155.4 6697861 6698022 R probably phage genome; hypothetical protein complement(6697861..6698022) Streptomyces avermitilis MA-4680 1216071 NP_826707.1 CDS SAV_5530 NC_003155.4 6698032 6698700 R probably phage genome; hypothetical protein complement(6698032..6698700) Streptomyces avermitilis MA-4680 1216072 NP_826708.1 CDS SAV_5531 NC_003155.4 6698718 6699254 R probably phage genome, PF05992: SbmA/BacA-like family; hypothetical protein complement(6698718..6699254) Streptomyces avermitilis MA-4680 1216073 NP_826709.1 CDS SAV_5532 NC_003155.4 6699251 6699643 R probably phage genome; hypothetical protein complement(6699251..6699643) Streptomyces avermitilis MA-4680 1216074 NP_826710.1 CDS SAV_5533 NC_003155.4 6699713 6700657 R probably phage genome; hypothetical protein complement(6699713..6700657) Streptomyces avermitilis MA-4680 1216075 NP_826711.1 CDS SAV_5534 NC_003155.4 6700777 6701424 R probably phage genome; hypothetical protein complement(6700777..6701424) Streptomyces avermitilis MA-4680 1216076 NP_826712.1 CDS SAV_5535 NC_003155.4 6702042 6702266 R probably phage genome; hypothetical protein complement(6702042..6702266) Streptomyces avermitilis MA-4680 1216077 NP_826713.1 CDS savM2 NC_003155.4 6702263 6703810 R probably phage genome, PF00145: C-5 cytosine-specific DNA methylase; type II restriction-modification system DNA cytosine-specific methylase complement(6702263..6703810) Streptomyces avermitilis MA-4680 1216078 NP_826714.1 CDS SAV_5537 NC_003155.4 6703791 6704228 R probably phage genome; hypothetical protein complement(6703791..6704228) Streptomyces avermitilis MA-4680 1216079 NP_826715.1 CDS SAV_5538 NC_003155.4 6704225 6704467 R probably phage genome; hypothetical protein complement(6704225..6704467) Streptomyces avermitilis MA-4680 1216080 NP_826716.1 CDS SAV_5539 NC_003155.4 6704464 6704691 R probably phage genome; hypothetical protein complement(6704464..6704691) Streptomyces avermitilis MA-4680 1216081 NP_826717.1 CDS SAV_5540 NC_003155.4 6704688 6705548 R probably phage genome, PF02498: BRO family, N-terminal domain; hypothetical protein complement(6704688..6705548) Streptomyces avermitilis MA-4680 1216082 NP_826718.1 CDS SAV_5541 NC_003155.4 6705772 6707229 D probably phage genome; hypothetical protein 6705772..6707229 Streptomyces avermitilis MA-4680 1216083 NP_826719.1 CDS SAV_5542 NC_003155.4 6707666 6708007 D probably phage genome; hypothetical protein 6707666..6708007 Streptomyces avermitilis MA-4680 1216084 NP_826720.1 CDS SAV_5543 NC_003155.4 6708308 6708553 D probably phage genome; hypothetical protein 6708308..6708553 Streptomyces avermitilis MA-4680 1216085 NP_826721.1 CDS SAV_5544 NC_003155.4 6708562 6708810 D probably phage genome; hypothetical protein 6708562..6708810 Streptomyces avermitilis MA-4680 1216086 NP_826722.1 CDS SAV_5545 NC_003155.4 6708789 6708980 D probably phage genome; hypothetical protein 6708789..6708980 Streptomyces avermitilis MA-4680 1216087 NP_826723.1 CDS SAV_5546 NC_003155.4 6709042 6709416 D probably phage genome; hypothetical protein 6709042..6709416 Streptomyces avermitilis MA-4680 1216088 NP_826724.1 CDS SAV_5547 NC_003155.4 6709505 6710344 D probably phage genome; hypothetical protein 6709505..6710344 Streptomyces avermitilis MA-4680 1216089 NP_826725.1 CDS int13 NC_003155.4 6710346 6711848 R probably phage genome, PF07508: Recombinase; integrase/recombinase complement(6710346..6711848) Streptomyces avermitilis MA-4680 1216090 NP_826726.1 CDS SAV_5549 NC_003155.4 6712190 6712546 D probably phage genome; hypothetical protein 6712190..6712546 Streptomyces avermitilis MA-4680 1216091 NP_826727.1 CDS SAV_5550 NC_003155.4 6712793 6713059 R probably phage genome, PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6712793..6713059) Streptomyces avermitilis MA-4680 1216092 NP_826728.1 CDS SAV_5551 NC_003155.4 6713593 6714810 D probably phage genome, PF06036: Streptomyces protein of unknown function (DUF921); hypothetical protein 6713593..6714810 Streptomyces avermitilis MA-4680 1216093 NP_826729.1 CDS spdA3 NC_003155.4 6715156 6715797 R probably phage genome; transfer protein spdA complement(6715156..6715797) Streptomyces avermitilis MA-4680 1211297 NP_826730.1 CDS SAV_5553 NC_003155.4 6717295 6717978 R probably phage genome; hypothetical protein complement(6717295..6717978) Streptomyces avermitilis MA-4680 1216094 NP_826731.1 CDS SAV_5554 NC_003155.4 6719527 6719781 R probably phage genome; hypothetical protein complement(6719527..6719781) Streptomyces avermitilis MA-4680 1216095 NP_826732.1 CDS int14 NC_003155.4 6719828 6721444 R probably phage genome, PF07508: Recombinase; integrase/recombinase complement(6719828..6721444) Streptomyces avermitilis MA-4680 1216096 NP_826733.1 CDS nhoA NC_003155.4 6721702 6722541 D PF00797: N-acetyltransferase; N-hydroxyarylamine O-acetyltransferase 6721702..6722541 Streptomyces avermitilis MA-4680 1211298 NP_826734.1 CDS SAV_5557 NC_003155.4 6722688 6722933 D hypothetical protein 6722688..6722933 Streptomyces avermitilis MA-4680 1216097 NP_826735.1 CDS SAV_5558 NC_003155.4 6723063 6724073 D DNA-binding protein 6723063..6724073 Streptomyces avermitilis MA-4680 1216098 NP_826736.1 CDS SAV_5559 NC_003155.4 6724127 6724297 D hypothetical protein 6724127..6724297 Streptomyces avermitilis MA-4680 1216099 NP_826737.1 CDS rpsT NC_003155.4 6724561 6724827 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(6724561..6724827) Streptomyces avermitilis MA-4680 1211299 NP_826738.1 CDS lepA NC_003155.4 6725081 6726949 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 6725081..6726949 Streptomyces avermitilis MA-4680 1211300 NP_826739.1 CDS fadD12 NC_003155.4 6727208 6729118 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase 6727208..6729118 Streptomyces avermitilis MA-4680 1211301 NP_826740.1 CDS SAV_5563 NC_003155.4 6729297 6729881 R two-component system response regulator complement(6729297..6729881) Streptomyces avermitilis MA-4680 1216100 NP_826741.1 CDS SAV_5564 NC_003155.4 6729894 6734045 R two-component system sensor kinase complement(6729894..6734045) Streptomyces avermitilis MA-4680 1216101 NP_826742.1 CDS prpK NC_003155.4 6734148 6736367 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 6734148..6736367 Streptomyces avermitilis MA-4680 1216102 NP_826743.1 CDS hemN NC_003155.4 6736403 6737635 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 6736403..6737635 Streptomyces avermitilis MA-4680 1211302 NP_826744.1 CDS SAV_5567 NC_003155.4 6737672 6738484 R hypothetical protein complement(6737672..6738484) Streptomyces avermitilis MA-4680 1216103 NP_826745.1 CDS blaB3 NC_003155.4 6738590 6739318 R PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase complement(6738590..6739318) Streptomyces avermitilis MA-4680 1211303 NP_826746.1 CDS hrcA NC_003155.4 6739510 6740526 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 6739510..6740526 Streptomyces avermitilis MA-4680 1211304 NP_826747.1 CDS dnaJ3 NC_003155.4 6740527 6741663 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 6740527..6741663 Streptomyces avermitilis MA-4680 1211305 NP_826748.1 CDS SAV_5571 NC_003155.4 6741854 6742927 D PF03060: 2-nitropropane dioxygenase; dioxygenase 6741854..6742927 Streptomyces avermitilis MA-4680 1216104 NP_826749.1 CDS sdrD NC_003155.4 6742924 6743673 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 6742924..6743673 Streptomyces avermitilis MA-4680 1211306 NP_826750.1 CDS SAV_5573 NC_003155.4 6743895 6744527 D lipoprotein 6743895..6744527 Streptomyces avermitilis MA-4680 1216105 NP_826751.1 CDS SAV_5574 NC_003155.4 6744599 6747820 D PF03572: Peptidase family S41; protease 6744599..6747820 Streptomyces avermitilis MA-4680 1216106 NP_826752.1 CDS SAV_5575 NC_003155.4 6747919 6748272 D PF01230: HIT domain; protein kinase C inhibitor 6747919..6748272 Streptomyces avermitilis MA-4680 1216107 NP_826753.1 CDS SAV_5576 NC_003155.4 6748279 6749184 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 6748279..6749184 Streptomyces avermitilis MA-4680 1216108 NP_826754.1 CDS add5 NC_003155.4 6749205 6750206 D catalyzes the formation of inosine from adenosine; adenosine deaminase 6749205..6750206 Streptomyces avermitilis MA-4680 1211307 NP_826755.1 CDS SAV_5578 NC_003155.4 6750219 6751508 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(6750219..6751508) Streptomyces avermitilis MA-4680 1216109 NP_826756.1 CDS SAV_5579 NC_003155.4 6751740 6752531 R IclR family transcriptional regulator complement(6751740..6752531) Streptomyces avermitilis MA-4680 1216110 NP_826757.1 CDS dapA3 NC_003155.4 6752657 6753652 D catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 6752657..6753652 Streptomyces avermitilis MA-4680 1211308 NP_826758.1 CDS gudD NC_003155.4 6753649 6755235 D glucarate dehydratase 6753649..6755235 Streptomyces avermitilis MA-4680 1211309 NP_826759.1 CDS SAV_5582 NC_003155.4 6755232 6756341 D carbohydrate kinase 6755232..6756341 Streptomyces avermitilis MA-4680 1216111 NP_826760.1 CDS phoH NC_003155.4 6756537 6757604 D phosphate starvation-induced protein 6756537..6757604 Streptomyces avermitilis MA-4680 1211310 NP_826761.1 CDS SAV_5584 NC_003155.4 6757634 6758131 D PF02130: Uncharacterized protein family UPF0054; putative metalloprotease 6757634..6758131 Streptomyces avermitilis MA-4680 1216112 NP_826762.1 CDS SAV_5585 NC_003155.4 6758128 6759435 D PF00571: CBS domain; transport protein 6758128..6759435 Streptomyces avermitilis MA-4680 1216113 NP_826763.1 CDS SAV_5586 NC_003155.4 6759432 6759791 D PF04237: Protein of unknown function (DUF419); MmcQ-like protein 6759432..6759791 Streptomyces avermitilis MA-4680 1216114 NP_826764.1 CDS SAV_5587 NC_003155.4 6759753 6761222 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(6759753..6761222) Streptomyces avermitilis MA-4680 1216115 NP_826765.1 CDS SAV_5588 NC_003155.4 6761429 6762298 D DNA-binding protein 6761429..6762298 Streptomyces avermitilis MA-4680 1216116 NP_826766.1 CDS SAV_5589 NC_003155.4 6762340 6762693 D hypothetical protein 6762340..6762693 Streptomyces avermitilis MA-4680 1216117 NP_826767.1 CDS SAV_5590 NC_003155.4 6763077 6763556 D hypothetical protein 6763077..6763556 Streptomyces avermitilis MA-4680 1216118 NP_826768.1 CDS SAV_5591 NC_003155.4 6763798 6765120 D hypothetical protein 6763798..6765120 Streptomyces avermitilis MA-4680 1216119 NP_826769.1 CDS SAV_5592 NC_003155.4 6765261 6766292 D hypothetical protein 6765261..6766292 Streptomyces avermitilis MA-4680 1216120 NP_826770.1 CDS glnB2 NC_003155.4 6766171 6766509 R regulatory protein for glutamine synthetase; glnB-homolog; nitrogen regulatory protein P-II complement(6766171..6766509) Streptomyces avermitilis MA-4680 1211311 NP_826771.1 CDS amtB2 NC_003155.4 6766506 6767816 R ammonium transporter complement(6766506..6767816) Streptomyces avermitilis MA-4680 1211312 NP_826772.1 CDS era NC_003155.4 6767983 6768975 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 6767983..6768975 Streptomyces avermitilis MA-4680 1211313 NP_826773.1 CDS SAV_5596 NC_003155.4 6769041 6769886 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(6769041..6769886) Streptomyces avermitilis MA-4680 1216121 NP_826774.1 CDS SAV_5597 NC_003155.4 6769929 6771194 R PF07690: Major Facilitator Superfamily; hypothetical protein complement(6769929..6771194) Streptomyces avermitilis MA-4680 1216122 NP_826775.1 CDS bglC3 NC_003155.4 6771191 6772516 R beta-glucosidase complement(6771191..6772516) Streptomyces avermitilis MA-4680 1211314 NP_826776.1 CDS SAV_5599 NC_003155.4 6772563 6772829 R hypothetical protein complement(6772563..6772829) Streptomyces avermitilis MA-4680 1216123 NP_826777.1 CDS SAV_5600 NC_003155.4 6772883 6773953 R PF02868: Thermolysin metallopeptidase, alpha-helical domain; metalloprotease complement(6772883..6773953) Streptomyces avermitilis MA-4680 1216124 NP_826778.2 CDS leuA2 NC_003155.4 6774355 6776049 D 2-isopropylmalate synthase 6774355..6776049 Streptomyces avermitilis MA-4680 1211315 NP_826779.1 CDS SAV_5602 NC_003155.4 6776234 6776959 D hypothetical protein 6776234..6776959 Streptomyces avermitilis MA-4680 1216125 NP_826780.1 CDS SAV_5603 NC_003155.4 6777171 6779249 D PF03176: MMPL family; hypothetical protein 6777171..6779249 Streptomyces avermitilis MA-4680 1216126 NP_826781.1 CDS SAV_5604 NC_003155.4 6779296 6780648 D two-component system sensor kinase 6779296..6780648 Streptomyces avermitilis MA-4680 1216127 NP_826782.1 CDS SAV_5605 NC_003155.4 6780660 6781343 D two-component system response regulator 6780660..6781343 Streptomyces avermitilis MA-4680 1216128 NP_826783.1 CDS SAV_5606 NC_003155.4 6781453 6782664 D neuramidase 6781453..6782664 Streptomyces avermitilis MA-4680 1216129 NP_826784.1 CDS dapA4 NC_003155.4 6782695 6783630 R dihydrodipicolinate synthase complement(6782695..6783630) Streptomyces avermitilis MA-4680 1211316 NP_826785.1 CDS SAV_5608 NC_003155.4 6783627 6784694 R ABC transporter ATP-binding protein complement(6783627..6784694) Streptomyces avermitilis MA-4680 1216130 NP_826786.1 CDS SAV_5609 NC_003155.4 6784691 6786649 R ABC transporter permease complement(6784691..6786649) Streptomyces avermitilis MA-4680 1216131 NP_826787.1 CDS SAV_5610 NC_003155.4 6786646 6787608 R ABC transporter permease complement(6786646..6787608) Streptomyces avermitilis MA-4680 1216132 NP_826788.1 CDS SAV_5611 NC_003155.4 6787628 6789259 R ABC transporter substrate-binding protein complement(6787628..6789259) Streptomyces avermitilis MA-4680 1216133 NP_826789.1 CDS SAV_5612 NC_003155.4 6789482 6790195 D GntR family transcriptional regulator 6789482..6790195 Streptomyces avermitilis MA-4680 1216134 NP_826790.1 CDS SAV_5613 NC_003155.4 6790221 6790655 D hypothetical protein 6790221..6790655 Streptomyces avermitilis MA-4680 1216135 NP_826791.1 CDS SAV_5614 NC_003155.4 6790707 6792146 R efflux protein complement(6790707..6792146) Streptomyces avermitilis MA-4680 1216136 NP_826792.1 CDS SAV_5615 NC_003155.4 6792152 6793180 R cysteine synthase (O-acetylserine sulfhydylase) complement(6792152..6793180) Streptomyces avermitilis MA-4680 1216137 NP_826793.1 CDS SAV_5616 NC_003155.4 6793223 6794596 R amino acid decarboxylase complement(6793223..6794596) Streptomyces avermitilis MA-4680 1216138 NP_826794.1 CDS arcB3 NC_003155.4 6794587 6795618 R ornithine cyclodeaminase complement(6794587..6795618) Streptomyces avermitilis MA-4680 1211317 NP_826795.1 CDS SAV_5618 NC_003155.4 6795641 6796633 R oxygenase complement(6795641..6796633) Streptomyces avermitilis MA-4680 1216139 NP_826796.1 CDS SAV_5619 NC_003155.4 6797004 6798554 D ABC transporter substrate-binding protein 6797004..6798554 Streptomyces avermitilis MA-4680 1216140 NP_826797.1 CDS SAV_5620 NC_003155.4 6798668 6799558 D ABC transporter permease 6798668..6799558 Streptomyces avermitilis MA-4680 1216141 NP_826798.1 CDS SAV_5621 NC_003155.4 6799555 6800403 D ABC transporter permease 6799555..6800403 Streptomyces avermitilis MA-4680 1216142 NP_826799.1 CDS SAV_5622 NC_003155.4 6800400 6801986 D ABC transporter ATP-binding protein 6800400..6801986 Streptomyces avermitilis MA-4680 1216143 NP_826800.1 CDS SAV_5623 NC_003155.4 6802201 6803397 D two-component system sensor kinase 6802201..6803397 Streptomyces avermitilis MA-4680 1216144 NP_826801.1 CDS SAV_5624 NC_003155.4 6803394 6804113 D two-component system response regulator 6803394..6804113 Streptomyces avermitilis MA-4680 1216145 NP_826802.1 CDS SAV_5625 NC_003155.4 6804091 6804363 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6804091..6804363) Streptomyces avermitilis MA-4680 1216146 NP_826803.1 CDS SAV_5626 NC_003155.4 6804345 6805178 R DNA-binding protein complement(6804345..6805178) Streptomyces avermitilis MA-4680 1216147 NP_826804.1 CDS SAV_5627 NC_003155.4 6805580 6805807 D hypothetical protein 6805580..6805807 Streptomyces avermitilis MA-4680 1216148 NP_826805.2 CDS recO NC_003155.4 6805880 6806626 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 6805880..6806626 Streptomyces avermitilis MA-4680 1216149 NP_826806.1 CDS uppS2 NC_003155.4 6806695 6807552 D UDP diphosphate synthase 6806695..6807552 Streptomyces avermitilis MA-4680 1211318 NP_826807.1 CDS SAV_5630 NC_003155.4 6807623 6810019 R PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease complement(6807623..6810019) Streptomyces avermitilis MA-4680 1216150 NP_826808.1 CDS SAV_5631 NC_003155.4 6810583 6810999 R metal uptake regulation protein complement(6810583..6810999) Streptomyces avermitilis MA-4680 1216151 NP_826809.1 CDS SAV_5632 NC_003155.4 6811058 6811954 R metal transport system ABC transporter permease complement(6811058..6811954) Streptomyces avermitilis MA-4680 1216152 NP_826810.1 CDS mntB NC_003155.4 6811954 6812766 R manganese/zinc transport system ABC transporter ATP-binding protein complement(6811954..6812766) Streptomyces avermitilis MA-4680 1211319 NP_826811.1 CDS SAV_5634 NC_003155.4 6812784 6813746 R metal transport system ABC transporter substrate-binding protein complement(6812784..6813746) Streptomyces avermitilis MA-4680 1216153 NP_826812.1 CDS glyS NC_003155.4 6813890 6815272 D Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 6813890..6815272 Streptomyces avermitilis MA-4680 1211320 NP_826813.1 CDS SAV_5636 NC_003155.4 6815383 6816435 R endochitinase complement(6815383..6816435) Streptomyces avermitilis MA-4680 1216154 NP_826814.1 CDS SAV_5637 NC_003155.4 6816672 6817688 D PF00248: Aldo/keto reductase family; oxidoreductase 6816672..6817688 Streptomyces avermitilis MA-4680 1216155 NP_826815.1 CDS SAV_5638 NC_003155.4 6817715 6818302 D TetR family transcriptional regulator 6817715..6818302 Streptomyces avermitilis MA-4680 1216156 NP_826816.1 CDS SAV_5639 NC_003155.4 6818362 6819186 R PF04672: Protein of unknown function (DUF574); hypothetical protein complement(6818362..6819186) Streptomyces avermitilis MA-4680 1216157 NP_826817.1 CDS SAV_5640 NC_003155.4 6819748 6820596 D hypothetical protein 6819748..6820596 Streptomyces avermitilis MA-4680 1216158 NP_826818.1 CDS SAV_5641 NC_003155.4 6820847 6822631 D hypothetical protein 6820847..6822631 Streptomyces avermitilis MA-4680 1216159 NP_826819.1 CDS SAV_5642 NC_003155.4 6822797 6823252 R hypothetical protein complement(6822797..6823252) Streptomyces avermitilis MA-4680 1216160 NP_826820.1 CDS SAV_5643 NC_003155.4 6823346 6823669 R hypothetical protein complement(6823346..6823669) Streptomyces avermitilis MA-4680 1216161 NP_826821.1 CDS SAV_5644 NC_003155.4 6823727 6824236 R MarR family transcriptional regulator complement(6823727..6824236) Streptomyces avermitilis MA-4680 1216162 NP_826822.1 CDS SAV_5645 NC_003155.4 6824343 6825134 D FMNH2-utilizing oxygenase 6824343..6825134 Streptomyces avermitilis MA-4680 1216163 NP_826823.1 CDS SAV_5646 NC_003155.4 6825131 6826558 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(6825131..6826558) Streptomyces avermitilis MA-4680 1216164 NP_826824.1 CDS SAV_5647 NC_003155.4 6826717 6827619 D DNA-binding protein 6826717..6827619 Streptomyces avermitilis MA-4680 1216165 NP_826825.1 CDS SAV_5648 NC_003155.4 6827627 6829072 R PF07690: Major Facilitator Superfamily; efflux membrane protein complement(6827627..6829072) Streptomyces avermitilis MA-4680 1216166 NP_826826.1 CDS dus NC_003155.4 6829246 6830451 D dihydrouridine synthase 6829246..6830451 Streptomyces avermitilis MA-4680 1216167 NP_826827.1 CDS SAV_5650 NC_003155.4 6830452 6832137 R PF00884: Sulfatase; hypothetical protein complement(6830452..6832137) Streptomyces avermitilis MA-4680 1216168 NP_826828.1 CDS SAV_5651 NC_003155.4 6832512 6834455 R hypothetical protein complement(6832512..6834455) Streptomyces avermitilis MA-4680 1216169 NP_826829.1 CDS SAV_5652 NC_003155.4 6834510 6836048 R PF06202: Amylo-alpha-1,6-glucosidase; hypothetical protein complement(6834510..6836048) Streptomyces avermitilis MA-4680 1216170 NP_826830.1 CDS SAV_5653 NC_003155.4 6836162 6837388 D transcriptional regulator 6836162..6837388 Streptomyces avermitilis MA-4680 1216171 NP_826831.1 CDS ppdK NC_003155.4 6837828 6840578 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 6837828..6840578 Streptomyces avermitilis MA-4680 1211321 NP_826832.1 CDS SAV_5655 NC_003155.4 6840721 6842214 R two-component system sensor kinase complement(6840721..6842214) Streptomyces avermitilis MA-4680 1216172 NP_826833.1 CDS SAV_5656 NC_003155.4 6842211 6843059 R two-component system response regulator complement(6842211..6843059) Streptomyces avermitilis MA-4680 1216173 NP_826834.1 CDS cynT2 NC_003155.4 6843298 6843903 D carbonic anhydrase 6843298..6843903 Streptomyces avermitilis MA-4680 1216174 NP_826835.1 CDS SAV_5658 NC_003155.4 6843900 6846017 D PF00916: Sulfate transporter family; transmembrane sulfate transport protein 6843900..6846017 Streptomyces avermitilis MA-4680 1216175 NP_826836.1 CDS SAV_5659 NC_003155.4 6846056 6846982 D PF00106: short chain dehydrogenase; dehydrogenase 6846056..6846982 Streptomyces avermitilis MA-4680 1216176 NP_826837.1 CDS nirD NC_003155.4 6847070 6847420 R nitrite reductase (NAD(P)H) small subunit complement(6847070..6847420) Streptomyces avermitilis MA-4680 1211322 NP_826838.1 CDS nirB NC_003155.4 6847417 6850023 R nitrite reductase (NAD(P)H) large subunit complement(6847417..6850023) Streptomyces avermitilis MA-4680 1211323 NP_826839.1 CDS SAV_5662 NC_003155.4 6850413 6851195 D PF01925: Domain of unknown function DUF81; hypothetical protein 6850413..6851195 Streptomyces avermitilis MA-4680 1216177 NP_826840.1 CDS SAV_5663 NC_003155.4 6851297 6851917 R PF04203: sortase family; protein complement(6851297..6851917) Streptomyces avermitilis MA-4680 1216178 NP_826841.1 CDS SAV_5664 NC_003155.4 6852035 6852544 R hypothetical protein complement(6852035..6852544) Streptomyces avermitilis MA-4680 1216179 NP_826842.1 CDS SAV_5665 NC_003155.4 6852929 6853573 D reductase 6852929..6853573 Streptomyces avermitilis MA-4680 1216180 NP_826843.1 CDS SAV_5666 NC_003155.4 6853604 6854281 R PF04264: YceI like family; hypothetical protein complement(6853604..6854281) Streptomyces avermitilis MA-4680 1216181 NP_826844.1 CDS SAV_5667 NC_003155.4 6854626 6855048 R MarR family transcriptional regulator complement(6854626..6855048) Streptomyces avermitilis MA-4680 1216182 NP_826845.1 CDS SAV_5668 NC_003155.4 6855110 6855859 D PF00561: alpha/beta hydrolase fold; hydrolase 6855110..6855859 Streptomyces avermitilis MA-4680 1216183 NP_826846.1 CDS SAV_5669 NC_003155.4 6855957 6857552 R PF02868: Thermolysin metallopeptidase, alpha-helical domain; neutral zinc metalloprotease complement(6855957..6857552) Streptomyces avermitilis MA-4680 1211324 NP_826847.1 CDS SAV_5670 NC_003155.4 6857841 6858284 D PF03674: Uncharacterised protein family (UPF0131); hypothetical protein 6857841..6858284 Streptomyces avermitilis MA-4680 1216184 NP_826848.1 CDS SAV_5671 NC_003155.4 6858335 6859426 D PF00775: Dioxygenase; protocatechuate dioxygenase 6858335..6859426 Streptomyces avermitilis MA-4680 1216185 NP_826849.1 CDS SAV_5672 NC_003155.4 6859503 6860195 R probable vancomycin sensitivity, PF02698: DUF218 domain; integral membrane protein complement(6859503..6860195) Streptomyces avermitilis MA-4680 1216186 NP_826850.1 CDS SAV_5673 NC_003155.4 6860373 6861293 D PF01903: CbiX; hypothetical protein 6860373..6861293 Streptomyces avermitilis MA-4680 1216187 NP_826851.1 CDS dgt NC_003155.4 6861343 6862695 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 6861343..6862695 Streptomyces avermitilis MA-4680 1211325 NP_826852.1 CDS fprD NC_003155.4 6862850 6864115 D ferredoxin reductase 6862850..6864115 Streptomyces avermitilis MA-4680 1211326 NP_826853.1 CDS dnaG NC_003155.4 6864460 6866358 D synthesizes RNA primers at the replication forks; DNA primase 6864460..6866358 Streptomyces avermitilis MA-4680 1211327 NP_826854.1 CDS SAV_5677 NC_003155.4 6866371 6867369 R hypothetical protein complement(6866371..6867369) Streptomyces avermitilis MA-4680 1216188 NP_826855.1 CDS SAV_5678 NC_003155.4 6867366 6868019 R hypothetical protein complement(6867366..6868019) Streptomyces avermitilis MA-4680 1216189 NP_826856.1 CDS sig47 NC_003155.4 6868347 6869516 D sigma-70 family; RNA polymerase sigma factor 6868347..6869516 Streptomyces avermitilis MA-4680 1211328 NP_826857.1 CDS SAV_5680 NC_003155.4 6869556 6871484 R ABC transporter ATP-binding protein complement(6869556..6871484) Streptomyces avermitilis MA-4680 1216190 NP_826858.1 CDS SAV_5681 NC_003155.4 6871484 6873217 R ABC transporter ATP-binding protein complement(6871484..6873217) Streptomyces avermitilis MA-4680 1216191 NP_826859.1 CDS SAV_5682 NC_003155.4 6873380 6873712 R hypothetical protein complement(6873380..6873712) Streptomyces avermitilis MA-4680 1216192 NP_826860.1 CDS xylB3 NC_003155.4 6873734 6874831 R xylulose kinase complement(6873734..6874831) Streptomyces avermitilis MA-4680 1216193 NP_826861.1 CDS SAV_5684 NC_003155.4 6875107 6875421 R hypothetical protein complement(6875107..6875421) Streptomyces avermitilis MA-4680 1216194 NP_826862.1 CDS SAV_5685 NC_003155.4 6876741 6877157 R transposase complement(6876741..6877157) Streptomyces avermitilis MA-4680 1216195 NP_826863.1 CDS SAV_5686 NC_003155.4 6877533 6879374 R ABC transporter ATP-binding protein complement(6877533..6879374) Streptomyces avermitilis MA-4680 1216196 NP_826864.1 CDS SAV_5687 NC_003155.4 6879386 6879820 R hypothetical protein complement(6879386..6879820) Streptomyces avermitilis MA-4680 1216197 NP_826865.1 CDS SAV_5688 NC_003155.4 6879817 6880104 R hypothetical protein complement(6879817..6880104) Streptomyces avermitilis MA-4680 1216198 NP_826866.1 CDS asnH2 NC_003155.4 6880101 6881873 R asparagine synthetase complement(6880101..6881873) Streptomyces avermitilis MA-4680 1216199 NP_826867.1 CDS SAV_5690 NC_003155.4 6882750 6883307 R hypothetical protein complement(6882750..6883307) Streptomyces avermitilis MA-4680 1216200 NP_826868.1 CDS SAV_5691 NC_003155.4 6883337 6883585 R hypothetical protein complement(6883337..6883585) Streptomyces avermitilis MA-4680 1216201 NP_826869.1 CDS SAV_5692 NC_003155.4 6883615 6883887 R hypothetical protein complement(6883615..6883887) Streptomyces avermitilis MA-4680 1216202 NP_826870.1 CDS SAV_5693 NC_003155.4 6884073 6884306 D hypothetical protein 6884073..6884306 Streptomyces avermitilis MA-4680 1216203 NP_826871.1 CDS SAV_5694 NC_003155.4 6884303 6884710 D PF01850: PIN domain; hypothetical protein 6884303..6884710 Streptomyces avermitilis MA-4680 1216204 NP_826872.1 CDS SAV_5695 NC_003155.4 6885756 6887651 D PF00350: Dynamin family; hypothetical protein 6885756..6887651 Streptomyces avermitilis MA-4680 1216205 NP_826873.1 CDS SAV_5696 NC_003155.4 6887655 6889511 D PF00350: Dynamin family; hypothetical protein 6887655..6889511 Streptomyces avermitilis MA-4680 1216206 NP_826874.1 CDS SAV_5697 NC_003155.4 6889508 6891487 D hypothetical protein 6889508..6891487 Streptomyces avermitilis MA-4680 1216207 NP_826875.1 CDS SAV_5698 NC_003155.4 6891487 6892749 D hypothetical protein 6891487..6892749 Streptomyces avermitilis MA-4680 1216208 NP_826876.1 CDS SAV_5699 NC_003155.4 6892750 6893244 D hypothetical protein 6892750..6893244 Streptomyces avermitilis MA-4680 1216209 NP_826877.1 CDS SAV_5700 NC_003155.4 6893160 6893864 R transcriptional regulator complement(6893160..6893864) Streptomyces avermitilis MA-4680 1216210 NP_826878.1 CDS SAV_5701 NC_003155.4 6894374 6895405 R LacI family transcriptional regulator complement(6894374..6895405) Streptomyces avermitilis MA-4680 1216211 NP_826879.1 CDS SAV_5702 NC_003155.4 6895482 6896318 R ABC transporter ATP-binding protein complement(6895482..6896318) Streptomyces avermitilis MA-4680 1216212 NP_826880.1 CDS SAV_5703 NC_003155.4 6896315 6897310 R sugar ABC transporter permease complement(6896315..6897310) Streptomyces avermitilis MA-4680 1216213 NP_826881.1 CDS SAV_5704 NC_003155.4 6897466 6898488 R sugar ABC transporter substrate-binding protein complement(6897466..6898488) Streptomyces avermitilis MA-4680 1216214 NP_826882.1 CDS scrK1 NC_003155.4 6898796 6899758 D fructokinase 6898796..6899758 Streptomyces avermitilis MA-4680 1211332 NP_826883.1 CDS SAV_5706 NC_003155.4 6899853 6900146 D PF03992: Antibiotic biosynthesis monooxygenase; hypothetical protein 6899853..6900146 Streptomyces avermitilis MA-4680 1216215 NP_826884.1 CDS SAV_5707 NC_003155.4 6900279 6900848 D hypothetical protein 6900279..6900848 Streptomyces avermitilis MA-4680 1216216 NP_826885.1 CDS SAV_5708 NC_003155.4 6901001 6901249 R hypothetical protein complement(6901001..6901249) Streptomyces avermitilis MA-4680 1216217 NP_826886.1 CDS SAV_5709 NC_003155.4 6901246 6902580 R PF00082: Subtilase family; protease complement(6901246..6902580) Streptomyces avermitilis MA-4680 1216218 NP_826887.1 CDS SAV_5710 NC_003155.4 6902814 6903446 R PF00156: Phosphoribosyl transferase domain; hypothetical protein complement(6902814..6903446) Streptomyces avermitilis MA-4680 1216219 NP_826888.1 CDS SAV_5711 NC_003155.4 6903717 6904673 D PF00561: alpha/beta hydrolase fold; hydrolase 6903717..6904673 Streptomyces avermitilis MA-4680 1216220 NP_826889.1 CDS SAV_5712 NC_003155.4 6904678 6908622 R ATP/GTP-binding protein complement(6904678..6908622) Streptomyces avermitilis MA-4680 1216221 NP_826890.1 CDS SAV_5713 NC_003155.4 6908619 6909953 R hypothetical protein complement(6908619..6909953) Streptomyces avermitilis MA-4680 1216222 NP_826891.1 CDS aac2 NC_003155.4 6910054 6910827 R aminoglycoside N3-acetyltransferase complement(6910054..6910827) Streptomyces avermitilis MA-4680 1211333 NP_826892.1 CDS SAV_5715 NC_003155.4 6910820 6912991 R PF04055: Radical SAM superfamily; hypothetical protein complement(6910820..6912991) Streptomyces avermitilis MA-4680 1216223 NP_826893.1 CDS SAV_5716 NC_003155.4 6913090 6913272 R hypothetical protein complement(6913090..6913272) Streptomyces avermitilis MA-4680 1216224 NP_826894.1 CDS SAV_5717 NC_003155.4 6913513 6914433 D hypothetical protein 6913513..6914433 Streptomyces avermitilis MA-4680 1216225 NP_826895.1 CDS SAV_5718 NC_003155.4 6914454 6914930 R hypothetical protein complement(6914454..6914930) Streptomyces avermitilis MA-4680 1216226 NP_826896.1 CDS SAV_5719 NC_003155.4 6915084 6916625 R two-component system sensor kinase complement(6915084..6916625) Streptomyces avermitilis MA-4680 1216227 NP_826897.1 CDS mreB2 NC_003155.4 6916653 6917690 R PF06723: MreB/Mbl protein; rod shape-determining protein MreB complement(6916653..6917690) Streptomyces avermitilis MA-4680 1211334 NP_826898.1 CDS SAV_5721 NC_003155.4 6918257 6921883 D PF00082: Subtilase family; protease 6918257..6921883 Streptomyces avermitilis MA-4680 1216228 NP_826899.1 CDS accD3 NC_003155.4 6921858 6923255 R acetyl CoA carboxylase beta subunit complement(6921858..6923255) Streptomyces avermitilis MA-4680 1211335 NP_826900.1 CDS fadD13 NC_003155.4 6923259 6924728 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(6923259..6924728) Streptomyces avermitilis MA-4680 1211336 NP_826901.1 CDS SAV_5724 NC_003155.4 6924844 6925422 R TetR family transcriptional regulator complement(6924844..6925422) Streptomyces avermitilis MA-4680 1216229 NP_826902.1 CDS SAV_5725 NC_003155.4 6925604 6925975 D hypothetical protein 6925604..6925975 Streptomyces avermitilis MA-4680 1216230 NP_826903.1 CDS SAV_5726 NC_003155.4 6926010 6926501 D PF00190: Cupin; hypothetical protein 6926010..6926501 Streptomyces avermitilis MA-4680 1216231 NP_826904.1 CDS prpH NC_003155.4 6926536 6927681 R PF00376: MerR family regulatory protein, PF00481: Protein phosphatase 2C; magnesium or manganese-dependent protein phosphatase complement(6926536..6927681) Streptomyces avermitilis MA-4680 1216232 NP_826905.1 CDS SAV_5728 NC_003155.4 6927832 6928704 D hypothetical protein 6927832..6928704 Streptomyces avermitilis MA-4680 1216233 NP_826906.1 CDS SAV_5729 NC_003155.4 6928685 6929347 R hypothetical protein complement(6928685..6929347) Streptomyces avermitilis MA-4680 1216234 NP_826907.1 CDS SAV_5730 NC_003155.4 6929295 6930134 R hypothetical protein complement(6929295..6930134) Streptomyces avermitilis MA-4680 1216235 NP_826908.1 CDS SAV_5731 NC_003155.4 6930131 6930352 R PF03966: Protein of unknown function (DUF343); hypothetical protein complement(6930131..6930352) Streptomyces avermitilis MA-4680 1216236 NP_826909.1 CDS SAV_5732 NC_003155.4 6930349 6931269 R hypothetical protein complement(6930349..6931269) Streptomyces avermitilis MA-4680 1216237 NP_826910.1 CDS SAV_5733 NC_003155.4 6931273 6932007 R PF05401: Nodulation protein S (NodS); hypothetical protein complement(6931273..6932007) Streptomyces avermitilis MA-4680 1216238 NP_826911.1 CDS SAV_5734 NC_003155.4 6932004 6933329 R PF00668: Condensation domain; hypothetical protein complement(6932004..6933329) Streptomyces avermitilis MA-4680 1216239 NP_826912.1 CDS SAV_5735 NC_003155.4 6933326 6937870 R PF00754: F5/8 type C domain; hypothetical protein complement(6933326..6937870) Streptomyces avermitilis MA-4680 1216240 NP_826913.1 CDS SAV_5736 NC_003155.4 6937867 6938592 R hypothetical protein complement(6937867..6938592) Streptomyces avermitilis MA-4680 1216241 NP_826914.1 CDS SAV_5737 NC_003155.4 6938589 6939824 R PF00534: Glycosyl transferases group 1; glycosyl transferase complement(6938589..6939824) Streptomyces avermitilis MA-4680 1216242 NP_826915.1 CDS SAV_5738 NC_003155.4 6940049 6941026 R hypothetical protein complement(6940049..6941026) Streptomyces avermitilis MA-4680 1216243 NP_826916.1 CDS SAV_5739 NC_003155.4 6941273 6941461 D hypothetical protein 6941273..6941461 Streptomyces avermitilis MA-4680 1216244 NP_826917.1 CDS SAV_5740 NC_003155.4 6941505 6942746 D regulatory protein 6941505..6942746 Streptomyces avermitilis MA-4680 1216245 NP_826918.1 CDS SAV_5741 NC_003155.4 6942974 6943747 D IclR family transcriptional regulator 6942974..6943747 Streptomyces avermitilis MA-4680 1216246 NP_826919.1 CDS SAV_5742 NC_003155.4 6943744 6944604 D calcium-binding protein 6943744..6944604 Streptomyces avermitilis MA-4680 1216247 NP_826920.1 CDS abfA NC_003155.4 6944863 6946374 D alpha-L-arabinofuranosidase 6944863..6946374 Streptomyces avermitilis MA-4680 1211337 NP_826921.1 CDS SAV_5744 NC_003155.4 6946518 6948203 R PF01833: IPT/TIG domain; hypothetical protein complement(6946518..6948203) Streptomyces avermitilis MA-4680 1216248 NP_826922.1 CDS SAV_5745 NC_003155.4 6948381 6948731 R hypothetical protein complement(6948381..6948731) Streptomyces avermitilis MA-4680 1216249 NP_826923.1 CDS SAV_5746 NC_003155.4 6948850 6950259 D two-component system sensor kinase 6948850..6950259 Streptomyces avermitilis MA-4680 1216250 NP_826924.1 CDS SAV_5747 NC_003155.4 6950247 6950894 D two-component system response regulator 6950247..6950894 Streptomyces avermitilis MA-4680 1216251 NP_826925.1 CDS SAV_5748 NC_003155.4 6950891 6951697 D lipoprotein 6950891..6951697 Streptomyces avermitilis MA-4680 1216252 NP_826926.1 CDS SAV_5749 NC_003155.4 6951786 6952241 R hypothetical protein complement(6951786..6952241) Streptomyces avermitilis MA-4680 1216253 NP_826927.1 CDS SAV_5750 NC_003155.4 6952272 6952784 R hypothetical protein complement(6952272..6952784) Streptomyces avermitilis MA-4680 1216254 NP_826928.1 CDS SAV_5751 NC_003155.4 6953421 6955928 D hypothetical protein 6953421..6955928 Streptomyces avermitilis MA-4680 1216255 NP_826929.1 CDS SAV_5752 NC_003155.4 6956080 6956331 D hypothetical protein 6956080..6956331 Streptomyces avermitilis MA-4680 1216256 NP_826930.1 CDS SAV_5753 NC_003155.4 6956717 6956959 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(6956717..6956959) Streptomyces avermitilis MA-4680 1216257 NP_826931.1 CDS SAV_5754 NC_003155.4 6956956 6957798 R DNA-binding protein complement(6956956..6957798) Streptomyces avermitilis MA-4680 1216258 NP_826932.1 CDS SAV_5755 NC_003155.4 6957927 6958385 D regulatory protein 6957927..6958385 Streptomyces avermitilis MA-4680 1216259 NP_826933.1 CDS bga7 NC_003155.4 6958393 6961323 R beta-galactosidase complement(6958393..6961323) Streptomyces avermitilis MA-4680 1211338 NP_826934.1 CDS SAV_5757 NC_003155.4 6961466 6961924 D transcriptional regulator 6961466..6961924 Streptomyces avermitilis MA-4680 1216260 NP_826935.1 CDS SAV_5758 NC_003155.4 6962101 6962970 R PF00775: Dioxygenase; protocatechuate dioxygenase complement(6962101..6962970) Streptomyces avermitilis MA-4680 1216261 NP_826936.1 CDS SAV_5759 NC_003155.4 6963098 6964288 R PF01360: Monooxygenase; monooxygenase complement(6963098..6964288) Streptomyces avermitilis MA-4680 1216262 NP_826937.1 CDS SAV_5760 NC_003155.4 6964312 6965106 R TetR family transcriptional regulator complement(6964312..6965106) Streptomyces avermitilis MA-4680 1216263 NP_826938.1 CDS SAV_5761 NC_003155.4 6965288 6966052 R PF00775: Dioxygenase; protocatechuate dioxygenase complement(6965288..6966052) Streptomyces avermitilis MA-4680 1216264 NP_826939.1 CDS SAV_5762 NC_003155.4 6966932 6967120 D hypothetical protein 6966932..6967120 Streptomyces avermitilis MA-4680 1216265 NP_826940.1 CDS SAV_5763 NC_003155.4 6967178 6967900 D ABC transporter ATP-binding protein 6967178..6967900 Streptomyces avermitilis MA-4680 1216266 NP_826941.1 CDS blaA4 NC_003155.4 6968103 6968936 D PF00144: Beta-lactamase; beta-lactamase 6968103..6968936 Streptomyces avermitilis MA-4680 1216267 NP_826942.1 CDS SAV_5765 NC_003155.4 6969006 6970655 R aminotransferase complement(6969006..6970655) Streptomyces avermitilis MA-4680 1216268 NP_826943.1 CDS galM1 NC_003155.4 6970843 6971994 R aldose 1-epimerase complement(6970843..6971994) Streptomyces avermitilis MA-4680 1211339 NP_826944.1 CDS SAV_5767 NC_003155.4 6972051 6973295 R sugar ABC transporter transport permease complement(6972051..6973295) Streptomyces avermitilis MA-4680 1216269 NP_826945.1 CDS SAV_5768 NC_003155.4 6973301 6974842 R sugar ABC transporter ATP-binding protein complement(6973301..6974842) Streptomyces avermitilis MA-4680 1216270 NP_826946.1 CDS SAV_5769 NC_003155.4 6974886 6975998 R sugar sugar ABC transporter substrate-binding protein complement(6974886..6975998) Streptomyces avermitilis MA-4680 1216271 NP_826947.1 CDS SAV_5770 NC_003155.4 6976141 6977109 R hypothetical protein complement(6976141..6977109) Streptomyces avermitilis MA-4680 1216272 NP_826948.1 CDS adhA7 NC_003155.4 6977202 6978206 R PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase complement(6977202..6978206) Streptomyces avermitilis MA-4680 1216273 NP_826949.1 CDS SAV_5772 NC_003155.4 6978203 6979360 R dehydratase complement(6978203..6979360) Streptomyces avermitilis MA-4680 1216274 NP_826950.1 CDS SAV_5773 NC_003155.4 6979650 6980393 D hypothetical protein 6979650..6980393 Streptomyces avermitilis MA-4680 1216275 NP_826951.1 CDS SAV_5774 NC_003155.4 6980613 6981416 R hypothetical protein complement(6980613..6981416) Streptomyces avermitilis MA-4680 1216276 NP_826952.1 CDS SAV_5775 NC_003155.4 6981481 6981912 R MarR family transcriptional regulator complement(6981481..6981912) Streptomyces avermitilis MA-4680 1216277 NP_826953.1 CDS SAV_5776 NC_003155.4 6982063 6983085 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 6982063..6983085 Streptomyces avermitilis MA-4680 1216278 NP_826954.1 CDS SAV_5777 NC_003155.4 6983345 6983533 R esterase complement(6983345..6983533) Streptomyces avermitilis MA-4680 1216279 NP_826955.1 CDS SAV_5778 NC_003155.4 6983557 6983796 R esterase complement(6983557..6983796) Streptomyces avermitilis MA-4680 1216280 NP_826956.1 CDS SAV_5779 NC_003155.4 6984012 6984974 D hypothetical protein 6984012..6984974 Streptomyces avermitilis MA-4680 1216281 NP_826957.1 CDS SAV_5780 NC_003155.4 6985071 6985787 D PF04401: Protein of unknown function (DUF540); integral membrane protein 6985071..6985787 Streptomyces avermitilis MA-4680 1216282 NP_826958.1 CDS SAV_5781 NC_003155.4 6985862 6987193 R PF01470: Pyroglutamyl peptidase; hypothetical protein complement(6985862..6987193) Streptomyces avermitilis MA-4680 1216283 NP_826959.1 CDS galM2 NC_003155.4 6987491 6988471 R aldose 1-epimerase complement(6987491..6988471) Streptomyces avermitilis MA-4680 1211340 NP_826960.1 CDS SAV_5783 NC_003155.4 6988499 6989401 R PF00657: GDSL-like Lipase/Acylhydrolase; lipoprotein complement(6988499..6989401) Streptomyces avermitilis MA-4680 1216284 NP_826961.1 CDS SAV_5784 NC_003155.4 6989596 6990090 D hypothetical protein 6989596..6990090 Streptomyces avermitilis MA-4680 1216285 NP_826962.1 CDS fabB1 NC_003155.4 6990166 6991437 R PF00109: Beta-ketoacyl synthase, N-terminal domain; 3-oxoacyl-ACP synthase II complement(6990166..6991437) Streptomyces avermitilis MA-4680 1211341 NP_826963.1 CDS acpP NC_003155.4 6991520 6991768 R carries the fatty acid chain in fatty acid biosynthesis; ACP complement(6991520..6991768) Streptomyces avermitilis MA-4680 1211342 NP_826964.1 CDS fabH1 NC_003155.4 6991839 6992906 R FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; 3-oxoacyl-ACP synthase III complement(6991839..6992906) Streptomyces avermitilis MA-4680 1211343 NP_826965.1 CDS fabD NC_003155.4 6992909 6993859 R PF00698: Acyl transferase domain; ACP S-malonyltransferase complement(6992909..6993859) Streptomyces avermitilis MA-4680 1211344 NP_826966.1 CDS SAV_5789 NC_003155.4 6993949 6995154 R hypothetical protein complement(6993949..6995154) Streptomyces avermitilis MA-4680 1216286 NP_826967.1 CDS SAV_5790 NC_003155.4 6995237 6995890 D PF02678: Pirin; hypothetical protein 6995237..6995890 Streptomyces avermitilis MA-4680 1216287 NP_826968.1 CDS blaA5 NC_003155.4 6995924 6996754 R PF00144: Beta-lactamase; beta-lactamase complement(6995924..6996754) Streptomyces avermitilis MA-4680 1216288 NP_826969.1 CDS SAV_5792 NC_003155.4 6996911 6997393 D MerR family transcriptional regulator 6996911..6997393 Streptomyces avermitilis MA-4680 1216289 NP_826970.1 CDS SAV_5793 NC_003155.4 6997390 6998406 D PF00248: Aldo/keto reductase family; oxidoreductase 6997390..6998406 Streptomyces avermitilis MA-4680 1216290 NP_826971.1 CDS SAV_5794 NC_003155.4 6998454 6999317 R hypothetical protein complement(6998454..6999317) Streptomyces avermitilis MA-4680 1216291 NP_826972.1 CDS SAV_5795 NC_003155.4 6999393 7000601 R PF06259: Domain of unknown function (DUF1023); protein complement(6999393..7000601) Streptomyces avermitilis MA-4680 1216292 NP_826973.1 CDS SAV_5796 NC_003155.4 7000776 7001456 R TetR family transcriptional regulator complement(7000776..7001456) Streptomyces avermitilis MA-4680 1216293 NP_826974.1 CDS tcmA NC_003155.4 7001572 7003194 D PF07690: Major Facilitator Superfamily; tetracenomycin C resistance and export protein 7001572..7003194 Streptomyces avermitilis MA-4680 1211345 NP_826975.1 CDS SAV_5798 NC_003155.4 7003435 7003746 D small hydrophobic protein 7003435..7003746 Streptomyces avermitilis MA-4680 1216294 NP_826976.1 CDS SAV_5799 NC_003155.4 7003857 7004684 R PF00520: Ion transport protein; ion transport integral membrane protein complement(7003857..7004684) Streptomyces avermitilis MA-4680 1216295 NP_826977.1 CDS aceE NC_003155.4 7004704 7007451 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(7004704..7007451) Streptomyces avermitilis MA-4680 1211346 NP_826978.1 CDS SAV_5801 NC_003155.4 7007846 7008325 D hypothetical protein 7007846..7008325 Streptomyces avermitilis MA-4680 1216296 NP_826979.1 CDS ahpE NC_003155.4 7008510 7008968 D thiol-specific antioxidant protein 7008510..7008968 Streptomyces avermitilis MA-4680 1211347 NP_826980.1 CDS terD3 NC_003155.4 7009081 7009656 D PF02342: Bacterial stress protein; tellurium resistance protein 7009081..7009656 Streptomyces avermitilis MA-4680 1216297 NP_826981.1 CDS terD4 NC_003155.4 7009785 7010360 D PF02342: Bacterial stress protein; tellurium resistance protein 7009785..7010360 Streptomyces avermitilis MA-4680 1216298 NP_826982.1 CDS SAV_5805 NC_003155.4 7010466 7011611 D PF04332: Protein of unknown function (DUF475); hypothetical protein 7010466..7011611 Streptomyces avermitilis MA-4680 1216299 NP_826983.1 CDS SAV_5806 NC_003155.4 7011775 7012509 D PF02342: Bacterial stress protein; hypothetical protein 7011775..7012509 Streptomyces avermitilis MA-4680 1216300 NP_826984.1 CDS SAV_5807 NC_003155.4 7012537 7013463 R PF02342: Bacterial stress protein; hypothetical protein complement(7012537..7013463) Streptomyces avermitilis MA-4680 1216301 NP_826985.1 CDS SAV_5808 NC_003155.4 7013655 7014818 D ATP/GTP-binding protein 7013655..7014818 Streptomyces avermitilis MA-4680 1216302 NP_826986.1 CDS SAV_5809 NC_003155.4 7014926 7017394 D hypothetical protein 7014926..7017394 Streptomyces avermitilis MA-4680 1216303 NP_826987.1 CDS SAV_5810 NC_003155.4 7017394 7018212 D hypothetical protein 7017394..7018212 Streptomyces avermitilis MA-4680 1216304 NP_826988.1 CDS SAV_5811 NC_003155.4 7018297 7018524 R hypothetical protein complement(7018297..7018524) Streptomyces avermitilis MA-4680 1216305 NP_826989.1 CDS SAV_5812 NC_003155.4 7018528 7019208 R hypothetical protein complement(7018528..7019208) Streptomyces avermitilis MA-4680 1216306 NP_826990.1 CDS SAV_5813 NC_003155.4 7019337 7020761 R PF01442: Apolipoprotein A1/A4/E family; hypothetical protein complement(7019337..7020761) Streptomyces avermitilis MA-4680 1216307 NP_826991.1 CDS SAV_5814 NC_003155.4 7020916 7021716 R lipoprotein complement(7020916..7021716) Streptomyces avermitilis MA-4680 1216308 NP_826992.1 CDS int15 NC_003155.4 7022151 7022579 R PF00589: Phage integrase family; integrase complement(7022151..7022579) Streptomyces avermitilis MA-4680 1216309 NP_826993.1 CDS SAV_5816 NC_003155.4 7023358 7024203 D hypothetical protein 7023358..7024203 Streptomyces avermitilis MA-4680 1216310 NP_826994.1 CDS SAV_5817 NC_003155.4 7024312 7025148 D hypothetical protein 7024312..7025148 Streptomyces avermitilis MA-4680 1216311 NP_826995.1 CDS SAV_5818 NC_003155.4 7025513 7025833 R hypothetical protein complement(7025513..7025833) Streptomyces avermitilis MA-4680 1216312 NP_826996.1 CDS SAV_5819 NC_003155.4 7025939 7026895 R PF02558: Ketopantoate reductase PanE/ApbA; oxidoreductase complement(7025939..7026895) Streptomyces avermitilis MA-4680 1216313 NP_826997.1 CDS SAV_5820 NC_003155.4 7027009 7027419 R hypothetical protein complement(7027009..7027419) Streptomyces avermitilis MA-4680 1216314 NP_826998.1 CDS SAV_5821 NC_003155.4 7027524 7027787 R hypothetical protein complement(7027524..7027787) Streptomyces avermitilis MA-4680 1216315 NP_826999.1 CDS SAV_5822 NC_003155.4 7027841 7028095 D hypothetical protein 7027841..7028095 Streptomyces avermitilis MA-4680 1216316 NP_827000.1 CDS SAV_5823 NC_003155.4 7028067 7028678 R PF00597: DedA family; hypothetical protein complement(7028067..7028678) Streptomyces avermitilis MA-4680 1216317 NP_827001.1 CDS SAV_5824 NC_003155.4 7028956 7029411 R PF07681: DoxX; hypothetical protein complement(7028956..7029411) Streptomyces avermitilis MA-4680 1216318 NP_827002.1 CDS SAV_5825 NC_003155.4 7029500 7031464 R hypothetical protein complement(7029500..7031464) Streptomyces avermitilis MA-4680 1216319 NP_827003.1 CDS SAV_5826 NC_003155.4 7031672 7033306 R hypothetical protein complement(7031672..7033306) Streptomyces avermitilis MA-4680 1216320 NP_827004.1 CDS SAV_5827 NC_003155.4 7033386 7034030 R protein complement(7033386..7034030) Streptomyces avermitilis MA-4680 1216321 NP_827005.1 CDS SAV_5828 NC_003155.4 7034613 7035194 D PF01169: Uncharacterized protein family UPF0016; hypothetical protein 7034613..7035194 Streptomyces avermitilis MA-4680 1216322 NP_827006.1 CDS SAV_5829 NC_003155.4 7035454 7036116 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 7035454..7036116 Streptomyces avermitilis MA-4680 1216323 NP_827007.1 CDS SAV_5830 NC_003155.4 7036327 7037331 R PF01471: Putative peptidoglycan binding domain; peptidoglycan-binding membrane protein complement(7036327..7037331) Streptomyces avermitilis MA-4680 1216324 NP_827008.1 CDS SAV_5831 NC_003155.4 7037506 7039593 D PF07690: Major Facilitator Superfamily; multidrug-efflux transporter 7037506..7039593 Streptomyces avermitilis MA-4680 1216325 NP_827009.1 CDS SAV_5832 NC_003155.4 7039590 7040132 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(7039590..7040132) Streptomyces avermitilis MA-4680 1216326 NP_827010.1 CDS SAV_5833 NC_003155.4 7040278 7041012 D protein 7040278..7041012 Streptomyces avermitilis MA-4680 1216327 NP_827011.1 CDS SAV_5834 NC_003155.4 7041018 7041797 D hypothetical protein 7041018..7041797 Streptomyces avermitilis MA-4680 1216328 NP_827012.1 CDS SAV_5835 NC_003155.4 7041912 7042325 R hypothetical protein complement(7041912..7042325) Streptomyces avermitilis MA-4680 1216329 NP_827013.1 CDS SAV_5836 NC_003155.4 7042375 7042836 D hypothetical protein 7042375..7042836 Streptomyces avermitilis MA-4680 1216330 NP_827014.1 CDS SAV_5837 NC_003155.4 7042860 7043534 R O-methyltransferase complement(7042860..7043534) Streptomyces avermitilis MA-4680 1216331 NP_827015.1 CDS SAV_5838 NC_003155.4 7043634 7044782 R hypothetical protein complement(7043634..7044782) Streptomyces avermitilis MA-4680 1216332 NP_827016.1 CDS SAV_5839 NC_003155.4 7044873 7046345 R PF00083: Sugar (and other) transporter; integral membrane transport protein complement(7044873..7046345) Streptomyces avermitilis MA-4680 1216333 NP_827017.1 CDS SAV_5840 NC_003155.4 7046733 7047638 D integral membrane protein 7046733..7047638 Streptomyces avermitilis MA-4680 1216334 NP_827018.1 CDS cyp22 NC_003155.4 7047868 7049112 R CYP125A2, fadA7 is located at upstream; cytochrome P450 hydroxylase complement(7047868..7049112) Streptomyces avermitilis MA-4680 1211349 NP_827019.1 CDS fadA7 NC_003155.4 7049394 7050563 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 7049394..7050563 Streptomyces avermitilis MA-4680 1211350 NP_827020.1 CDS SAV_5843 NC_003155.4 7050588 7051283 R PF06912: Protein of unknown function (DUF1275); hypothetical protein complement(7050588..7051283) Streptomyces avermitilis MA-4680 1216335 NP_827021.1 CDS SAV_5844 NC_003155.4 7051388 7052638 D PF03583: Secretory lipase; hypothetical protein 7051388..7052638 Streptomyces avermitilis MA-4680 1216336 NP_827022.1 CDS SAV_5845 NC_003155.4 7052717 7053178 R PF06737: Transglycosylase-like domain; hypothetical protein complement(7052717..7053178) Streptomyces avermitilis MA-4680 1216337 NP_827023.1 CDS SAV_5846 NC_003155.4 7053469 7054434 R integral membrane protein complement(7053469..7054434) Streptomyces avermitilis MA-4680 1216338 NP_827024.1 CDS SAV_5847 NC_003155.4 7054431 7056116 R ABC transporter ATP-binding protein complement(7054431..7056116) Streptomyces avermitilis MA-4680 1216339 NP_827025.1 CDS SAV_5848 NC_003155.4 7056113 7057258 R PF02361: Cobalt transport protein; integral membrane protein complement(7056113..7057258) Streptomyces avermitilis MA-4680 1216340 NP_827026.1 CDS SAV_5849 NC_003155.4 7057265 7057939 R hypothetical protein complement(7057265..7057939) Streptomyces avermitilis MA-4680 1216341 NP_827027.1 CDS SAV_5850 NC_003155.4 7057936 7059213 R PF00432: Prenyltransferase and squalene oxidase repeat; hypothetical protein complement(7057936..7059213) Streptomyces avermitilis MA-4680 1216342 NP_827028.1 CDS SAV_5851 NC_003155.4 7059531 7060649 R PF00753: Metallo-beta-lactamase superfamily; hypothetical protein complement(7059531..7060649) Streptomyces avermitilis MA-4680 1216343 NP_827029.1 CDS SAV_5852 NC_003155.4 7060741 7062249 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 7060741..7062249 Streptomyces avermitilis MA-4680 1216344 NP_827030.1 CDS fdxF NC_003155.4 7062249 7062482 D ferredoxin 7062249..7062482 Streptomyces avermitilis MA-4680 1211351 NP_827031.1 CDS SAV_5854 NC_003155.4 7062720 7063376 R TetR family transcriptional regulator complement(7062720..7063376) Streptomyces avermitilis MA-4680 1216345 NP_827032.1 CDS SAV_5855 NC_003155.4 7063585 7065060 D PF00534: Glycosyl transferases group 1; glycosyl transferase 7063585..7065060 Streptomyces avermitilis MA-4680 1216346 NP_827033.1 CDS SAV_5856 NC_003155.4 7065054 7065800 D methyltransferase 7065054..7065800 Streptomyces avermitilis MA-4680 1216347 NP_827034.1 CDS SAV_5857 NC_003155.4 7065797 7066867 D hypothetical protein 7065797..7066867 Streptomyces avermitilis MA-4680 1216348 NP_827035.1 CDS SAV_5858 NC_003155.4 7066928 7067221 R hypothetical protein complement(7066928..7067221) Streptomyces avermitilis MA-4680 1216349 NP_827036.1 CDS SAV_5859 NC_003155.4 7067360 7067920 D hypothetical protein 7067360..7067920 Streptomyces avermitilis MA-4680 1216350 NP_827037.1 CDS SAV_5860 NC_003155.4 7068139 7068789 D hypothetical protein 7068139..7068789 Streptomyces avermitilis MA-4680 1216351 NP_827038.1 CDS SAV_5861 NC_003155.4 7068812 7069810 D PF01520: N-acetylmuramoyl-L-alanine amidase; hypothetical protein 7068812..7069810 Streptomyces avermitilis MA-4680 1216352 NP_827039.1 CDS SAV_5862 NC_003155.4 7069951 7070586 R hypothetical protein complement(7069951..7070586) Streptomyces avermitilis MA-4680 1216353 NP_827040.1 CDS SAV_5863 NC_003155.4 7070987 7071784 D integral membrane protein 7070987..7071784 Streptomyces avermitilis MA-4680 1216354 NP_827041.1 CDS SAV_5864 NC_003155.4 7071899 7072909 D PF00296: Luciferase-like monooxygenase; FMN-dependent monooxygenase 7071899..7072909 Streptomyces avermitilis MA-4680 1216355 NP_827042.1 CDS SAV_5865 NC_003155.4 7073034 7074785 R PF07690: Major Facilitator Superfamily; membrane transport protein complement(7073034..7074785) Streptomyces avermitilis MA-4680 1216356 NP_827043.1 CDS ltp1 NC_003155.4 7074961 7076199 D lipid-transfer protein 7074961..7076199 Streptomyces avermitilis MA-4680 1211352 NP_827044.1 CDS SAV_5867 NC_003155.4 7076342 7077796 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 7076342..7077796 Streptomyces avermitilis MA-4680 1216357 NP_827045.1 CDS SAV_5868 NC_003155.4 7077847 7078479 R two-component system response regulator complement(7077847..7078479) Streptomyces avermitilis MA-4680 1216358 NP_827046.1 CDS SAV_5869 NC_003155.4 7078512 7079885 R two-component system sensor kinase complement(7078512..7079885) Streptomyces avermitilis MA-4680 1216359 NP_827047.1 CDS SAV_5870 NC_003155.4 7080294 7081151 D UfaA2 protein 7080294..7081151 Streptomyces avermitilis MA-4680 1216360 NP_827048.1 CDS SAV_5871 NC_003155.4 7081196 7082272 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 7081196..7082272 Streptomyces avermitilis MA-4680 1216361 NP_827049.1 CDS fabG NC_003155.4 7082308 7083282 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 7082308..7083282 Streptomyces avermitilis MA-4680 1211353 NP_827050.1 CDS SAV_5873 NC_003155.4 7083426 7083590 R hypothetical protein complement(7083426..7083590) Streptomyces avermitilis MA-4680 1216362 NP_827051.1 CDS SAV_5874 NC_003155.4 7083639 7084970 R hypothetical protein complement(7083639..7084970) Streptomyces avermitilis MA-4680 1216363 NP_827052.1 CDS SAV_5875 NC_003155.4 7085244 7086107 D PF01784: NIF3 (NGG1p interacting factor 3); NGG1-interacting factor 3 7085244..7086107 Streptomyces avermitilis MA-4680 1216364 NP_827053.1 CDS SAV_5876 NC_003155.4 7086257 7086847 D PF02591: Uncharacterized ACR, COG1579; hypothetical protein 7086257..7086847 Streptomyces avermitilis MA-4680 1216365 NP_827054.1 CDS SAV_5877 NC_003155.4 7086857 7088173 D bifunctional RNase H/acid phosphatase 7086857..7088173 Streptomyces avermitilis MA-4680 1216366 NP_827055.1 CDS kdgA NC_003155.4 7088283 7088942 R 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase complement(7088283..7088942) Streptomyces avermitilis MA-4680 1211354 NP_827056.1 CDS SAV_5879 NC_003155.4 7089039 7089839 R PF03883: Protein of unknown function (DUF328); hypothetical protein complement(7089039..7089839) Streptomyces avermitilis MA-4680 1216367 NP_827057.1 CDS rnr NC_003155.4 7090363 7091718 D PF00773: RNB-like protein; ribonuclease R 7090363..7091718 Streptomyces avermitilis MA-4680 1216368 NP_827058.1 CDS SAV_5881 NC_003155.4 7091804 7092652 D AraC family transcription regulator 7091804..7092652 Streptomyces avermitilis MA-4680 1216369 NP_827059.1 CDS SAV_5882 NC_003155.4 7092672 7093748 D PF00892: Integral membrane protein DUF6; integral membrane protein 7092672..7093748 Streptomyces avermitilis MA-4680 1216370 NP_827060.1 CDS SAV_5883 NC_003155.4 7094601 7095764 R O-methyltransferase complement(7094601..7095764) Streptomyces avermitilis MA-4680 1216371 NP_827061.1 CDS SAV_5884 NC_003155.4 7095761 7096726 R hypothetical protein complement(7095761..7096726) Streptomyces avermitilis MA-4680 1216372 NP_827062.1 CDS SAV_5885 NC_003155.4 7096726 7096986 R hypothetical protein complement(7096726..7096986) Streptomyces avermitilis MA-4680 1216373 NP_827063.1 CDS SAV_5886 NC_003155.4 7097219 7097425 R hypothetical protein complement(7097219..7097425) Streptomyces avermitilis MA-4680 1216374 NP_827064.1 CDS SAV_5887 NC_003155.4 7097918 7099063 D PF06036: Streptomyces protein of unknown function (DUF921); hypothetical protein 7097918..7099063 Streptomyces avermitilis MA-4680 1216375 NP_827065.1 CDS SAV_5888 NC_003155.4 7099080 7099433 D hypothetical protein 7099080..7099433 Streptomyces avermitilis MA-4680 1216376 NP_827066.1 CDS SAV_5889 NC_003155.4 7099811 7100128 R hypothetical protein complement(7099811..7100128) Streptomyces avermitilis MA-4680 1216377 NP_827067.1 CDS SAV_5890 NC_003155.4 7100211 7101026 D PF04672: Protein of unknown function (DUF574); hypothetical protein 7100211..7101026 Streptomyces avermitilis MA-4680 1216378 NP_827068.1 CDS SAV_5891 NC_003155.4 7101223 7101762 D PF05079: Protein of unknown function (DUF680); hypothetical protein 7101223..7101762 Streptomyces avermitilis MA-4680 1216379 NP_827069.1 CDS SAV_5892 NC_003155.4 7101854 7102672 R hypothetical protein complement(7101854..7102672) Streptomyces avermitilis MA-4680 1216380 NP_827070.1 CDS SAV_5893 NC_003155.4 7102713 7103246 R hypothetical protein complement(7102713..7103246) Streptomyces avermitilis MA-4680 1216381 NP_827071.1 CDS SAV_5894 NC_003155.4 7103213 7104490 R mceF, PF02470: mce related protein; mce-related protein complement(7103213..7104490) Streptomyces avermitilis MA-4680 1216382 NP_827072.1 CDS SAV_5895 NC_003155.4 7104487 7105764 R mceE, PF02470: mce related protein; mce-related protein complement(7104487..7105764) Streptomyces avermitilis MA-4680 1216383 NP_827073.1 CDS SAV_5896 NC_003155.4 7105761 7106885 R mceD, PF02470: mce related protein; mce-related protein complement(7105761..7106885) Streptomyces avermitilis MA-4680 1216384 NP_827074.1 CDS SAV_5897 NC_003155.4 7106882 7108060 R mceC, PF02470: mce related protein; mce-related protein complement(7106882..7108060) Streptomyces avermitilis MA-4680 1216385 NP_827075.1 CDS SAV_5898 NC_003155.4 7108057 7109148 R mceB, PF02470: mce related protein; mce-related protein complement(7108057..7109148) Streptomyces avermitilis MA-4680 1216386 NP_827076.1 CDS SAV_5899 NC_003155.4 7109145 7110392 R mceA, PF02470: mce related protein; mce-related protein complement(7109145..7110392) Streptomyces avermitilis MA-4680 1216387 NP_827077.1 CDS SAV_5900 NC_003155.4 7110389 7111192 R ABC transporter permease complement(7110389..7111192) Streptomyces avermitilis MA-4680 1216388 NP_827078.1 CDS SAV_5901 NC_003155.4 7111196 7111966 R ABC transporter permease complement(7111196..7111966) Streptomyces avermitilis MA-4680 1216389 NP_827079.1 CDS SAV_5902 NC_003155.4 7111963 7112943 R ABC transporter ATP-binding protein complement(7111963..7112943) Streptomyces avermitilis MA-4680 1216390 NP_827080.1 CDS sig48 NC_003155.4 7113078 7114112 R ECF subfamily RNA polymerase sigma factor complement(7113078..7114112) Streptomyces avermitilis MA-4680 1211355 NP_827081.1 CDS SAV_5904 NC_003155.4 7114167 7115219 R PF01464: Transglycosylase SLT domain; protein complement(7114167..7115219) Streptomyces avermitilis MA-4680 1216391 NP_827082.1 CDS SAV_5905 NC_003155.4 7115405 7117315 R hypothetical protein complement(7115405..7117315) Streptomyces avermitilis MA-4680 1216392 NP_827083.1 CDS SAV_5906 NC_003155.4 7117325 7117882 R hypothetical protein complement(7117325..7117882) Streptomyces avermitilis MA-4680 1216393 NP_827084.1 CDS SAV_5907 NC_003155.4 7118092 7119543 R hypothetical protein complement(7118092..7119543) Streptomyces avermitilis MA-4680 1216394 NP_827085.1 CDS SAV_5908 NC_003155.4 7119676 7120029 R PF03819: MazG nucleotide pyrophosphohydrolase domain; hypothetical protein complement(7119676..7120029) Streptomyces avermitilis MA-4680 1216395 NP_827086.1 CDS SAV_5909 NC_003155.4 7120052 7120597 R PF07681: DoxX; hypothetical protein complement(7120052..7120597) Streptomyces avermitilis MA-4680 1216396 NP_827087.1 CDS SAV_5910 NC_003155.4 7120763 7121089 D hypothetical protein 7120763..7121089 Streptomyces avermitilis MA-4680 1216397 NP_827088.1 CDS SAV_5911 NC_003155.4 7121220 7121960 R ABC transporter ATP-binding protein complement(7121220..7121960) Streptomyces avermitilis MA-4680 1216398 NP_827089.1 CDS SAV_5912 NC_003155.4 7122065 7123522 R PF02687: Predicted permease; integral membrane protein complement(7122065..7123522) Streptomyces avermitilis MA-4680 1216399 NP_827090.1 CDS dacF NC_003155.4 7123858 7125198 D PF00768: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 7123858..7125198 Streptomyces avermitilis MA-4680 1211356 NP_827091.1 CDS SAV_5914 NC_003155.4 7125477 7126298 R PF00106: short chain dehydrogenase; dehydrogenase complement(7125477..7126298) Streptomyces avermitilis MA-4680 1216400 NP_827092.1 CDS phoA NC_003155.4 7126402 7128048 D alkaline phosphatase 7126402..7128048 Streptomyces avermitilis MA-4680 1211357 NP_827093.1 CDS SAV_5916 NC_003155.4 7128195 7129202 R PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase complement(7128195..7129202) Streptomyces avermitilis MA-4680 1216401 NP_827094.1 CDS SAV_5917 NC_003155.4 7129278 7130717 D PF07690: Major Facilitator Superfamily; bicyclomycin resistance protein 7129278..7130717 Streptomyces avermitilis MA-4680 1216402 NP_827095.1 CDS blaA6 NC_003155.4 7130795 7131844 D PF00144: Beta-lactamase; beta-lactamase 7130795..7131844 Streptomyces avermitilis MA-4680 1216403 NP_827096.1 CDS SAV_5919 NC_003155.4 7131857 7132855 D hypothetical protein 7131857..7132855 Streptomyces avermitilis MA-4680 1216404 NP_827097.1 CDS SAV_5920 NC_003155.4 7132960 7133619 D TetR family transcriptional regulator 7132960..7133619 Streptomyces avermitilis MA-4680 1216405 NP_827098.1 CDS glpQ7 NC_003155.4 7133588 7134478 R glycerophosphoryl diester phosphodiesterase complement(7133588..7134478) Streptomyces avermitilis MA-4680 1216406 NP_827099.1 CDS SAV_5922 NC_003155.4 7134665 7135393 D hypothetical protein 7134665..7135393 Streptomyces avermitilis MA-4680 1216407 NP_827100.1 CDS SAV_5923 NC_003155.4 7135421 7136491 R hypothetical protein complement(7135421..7136491) Streptomyces avermitilis MA-4680 1216408 NP_827101.1 CDS SAV_5924 NC_003155.4 7136524 7137390 R PF03239: Iron permease FTR1 family; hypothetical protein complement(7136524..7137390) Streptomyces avermitilis MA-4680 1216409 NP_827102.1 CDS SAV_5925 NC_003155.4 7137394 7138692 R This family of dye-decolourising peroxidases lack a typical heme-binding region; iron-dependent peroxidase complement(7137394..7138692) Streptomyces avermitilis MA-4680 1216410 NP_827103.1 CDS SAV_5926 NC_003155.4 7138689 7139837 R PF04302: Protein of unknown function (DUF451); lipoprotein complement(7138689..7139837) Streptomyces avermitilis MA-4680 1216411 NP_827104.1 CDS SAV_5927 NC_003155.4 7139994 7140248 R hypothetical protein complement(7139994..7140248) Streptomyces avermitilis MA-4680 1216412 NP_827105.1 CDS SAV_5928 NC_003155.4 7140301 7141176 D hypothetical protein 7140301..7141176 Streptomyces avermitilis MA-4680 1216413 NP_827106.1 CDS SAV_5929 NC_003155.4 7141169 7141813 D PF02567: phenazine biosynthesis-like protein; hypothetical protein 7141169..7141813 Streptomyces avermitilis MA-4680 1216414 NP_827107.1 CDS hmuO NC_003155.4 7141893 7142540 R heme oxygenase complement(7141893..7142540) Streptomyces avermitilis MA-4680 1216415 NP_827108.1 CDS map4 NC_003155.4 7142715 7143572 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(7142715..7143572) Streptomyces avermitilis MA-4680 1216416 NP_827109.1 CDS SAV_5932 NC_003155.4 7143631 7143867 D hypothetical protein 7143631..7143867 Streptomyces avermitilis MA-4680 1216417 NP_827110.1 CDS SAV_5933 NC_003155.4 7144040 7144648 R hypothetical protein complement(7144040..7144648) Streptomyces avermitilis MA-4680 1216418 NP_827111.1 CDS SAV_5934 NC_003155.4 7144755 7145828 D neuramidase 7144755..7145828 Streptomyces avermitilis MA-4680 1216419 NP_827112.1 CDS SAV_5935 NC_003155.4 7145867 7146571 D PF03807: NADP oxidoreductase coenzyme F420-dependent; NADPH-dependent F420 reductase 7145867..7146571 Streptomyces avermitilis MA-4680 1216420 NP_827113.1 CDS SAV_5936 NC_003155.4 7146634 7146816 D hypothetical protein 7146634..7146816 Streptomyces avermitilis MA-4680 1216421 NP_827114.1 CDS SAV_5937 NC_003155.4 7146806 7147606 R PF02163: Peptidase family M50; hypothetical protein complement(7146806..7147606) Streptomyces avermitilis MA-4680 1216422 NP_827115.1 CDS SAV_5938 NC_003155.4 7147711 7148265 D hypothetical protein 7147711..7148265 Streptomyces avermitilis MA-4680 1216423 NP_827116.1 CDS SAV_5939 NC_003155.4 7148262 7151792 D hypothetical protein 7148262..7151792 Streptomyces avermitilis MA-4680 1216424 NP_827117.1 CDS SAV_5940 NC_003155.4 7151814 7152632 R ABC transporter permease complement(7151814..7152632) Streptomyces avermitilis MA-4680 1216425 NP_827118.1 CDS SAV_5941 NC_003155.4 7152629 7153669 R ABC transporter ATP-binding protein complement(7152629..7153669) Streptomyces avermitilis MA-4680 1216426 NP_827119.1 CDS SAV_5942 NC_003155.4 7153958 7154353 D hypothetical protein 7153958..7154353 Streptomyces avermitilis MA-4680 1216427 NP_827120.1 CDS panB NC_003155.4 7154378 7155241 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(7154378..7155241) Streptomyces avermitilis MA-4680 1211358 NP_827121.1 CDS SAV_5944 NC_003155.4 7155444 7157036 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 7155444..7157036 Streptomyces avermitilis MA-4680 1216428 NP_827122.1 CDS SAV_5945 NC_003155.4 7157137 7157757 D TetR family transcriptional regulator 7157137..7157757 Streptomyces avermitilis MA-4680 1216429 NP_827123.1 CDS SAV_5946 NC_003155.4 7158034 7159071 D PF03372: Endonuclease/Exonuclease/phosphatase family; hypothetical protein 7158034..7159071 Streptomyces avermitilis MA-4680 1216430 NP_827124.1 CDS SAV_5947 NC_003155.4 7159217 7160443 D similar to cmlR, PF07690: Major Facilitator Superfamily; transmembrane efflux protein 7159217..7160443 Streptomyces avermitilis MA-4680 1216431 NP_827125.1 CDS nadE NC_003155.4 7160537 7162291 R NH(3)-dependent NAD(+) synthetase complement(7160537..7162291) Streptomyces avermitilis MA-4680 1211359 NP_827126.1 CDS SAV_5949 NC_003155.4 7162675 7164576 R PF00082: Subtilase family; serine protease complement(7162675..7164576) Streptomyces avermitilis MA-4680 1216432 NP_827127.1 CDS SAV_5950 NC_003155.4 7164894 7165520 R PF03713: Domain of unknown function (DUF305); protein complement(7164894..7165520) Streptomyces avermitilis MA-4680 1216433 NP_827128.1 CDS SAV_5951 NC_003155.4 7165517 7166185 R hypothetical protein complement(7165517..7166185) Streptomyces avermitilis MA-4680 1216434 NP_827129.1 CDS SAV_5952 NC_003155.4 7166321 7166821 D PF02082: Transcriptional regulator; hypothetical protein 7166321..7166821 Streptomyces avermitilis MA-4680 1216435 NP_827130.1 CDS fhbB NC_003155.4 7166776 7167978 R flavohemoprotein complement(7166776..7167978) Streptomyces avermitilis MA-4680 1216436 NP_827131.1 CDS glnA1 NC_003155.4 7168307 7169668 D glutamine synthetase 7168307..7169668 Streptomyces avermitilis MA-4680 1211360 NP_827132.1 CDS SAV_5955 NC_003155.4 7169746 7170057 R hypothetical protein complement(7169746..7170057) Streptomyces avermitilis MA-4680 1216437 NP_827133.1 CDS SAV_5956 NC_003155.4 7170364 7170603 D hypothetical protein 7170364..7170603 Streptomyces avermitilis MA-4680 1216438 NP_827134.1 CDS SAV_5957 NC_003155.4 7170603 7171262 D hypothetical protein 7170603..7171262 Streptomyces avermitilis MA-4680 1216439 NP_827135.1 CDS SAV_5958 NC_003155.4 7171640 7173271 D hypothetical protein 7171640..7173271 Streptomyces avermitilis MA-4680 1216440 NP_827136.1 CDS SAV_5959 NC_003155.4 7173320 7176457 D LuxR family transcriptional regulator 7173320..7176457 Streptomyces avermitilis MA-4680 1216441 NP_827137.1 CDS SAV_5960 NC_003155.4 7176435 7177229 R ABC transporter permease complement(7176435..7177229) Streptomyces avermitilis MA-4680 1216442 NP_827138.1 CDS SAV_5961 NC_003155.4 7177226 7178224 R ABC transporter ATP-binding protein complement(7177226..7178224) Streptomyces avermitilis MA-4680 1216443 NP_827139.1 CDS SAV_5962 NC_003155.4 7178491 7179432 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(7178491..7179432) Streptomyces avermitilis MA-4680 1216444 NP_827140.1 CDS SAV_5963 NC_003155.4 7179438 7180094 R hypothetical protein complement(7179438..7180094) Streptomyces avermitilis MA-4680 1216445 NP_827141.1 CDS SAV_5964 NC_003155.4 7180384 7180920 R hypothetical protein complement(7180384..7180920) Streptomyces avermitilis MA-4680 1216446 NP_827142.1 CDS SAV_5965 NC_003155.4 7182115 7182849 R PF01738: Dienelactone hydrolase family; hydrolase complement(7182115..7182849) Streptomyces avermitilis MA-4680 1216447 NP_827143.1 CDS SAV_5966 NC_003155.4 7183132 7183341 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(7183132..7183341) Streptomyces avermitilis MA-4680 1216448 NP_827144.1 CDS SAV_5968 NC_003155.4 7183338 7183568 R hypothetical protein complement(7183338..7183568) Streptomyces avermitilis MA-4680 1216449 NP_827145.1 CDS SAV_5967 NC_003155.4 7183542 7183754 D hypothetical protein 7183542..7183754 Streptomyces avermitilis MA-4680 1216450 NP_827146.1 CDS SAV_5969 NC_003155.4 7183804 7184826 R hypothetical protein complement(7183804..7184826) Streptomyces avermitilis MA-4680 1216451 NP_827147.1 CDS SAV_5970 NC_003155.4 7184823 7186142 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(7184823..7186142) Streptomyces avermitilis MA-4680 1216452 NP_827148.1 CDS SAV_5971 NC_003155.4 7186144 7187037 R acid phosphatase complement(7186144..7187037) Streptomyces avermitilis MA-4680 1216453 NP_827149.1 CDS glnE NC_003155.4 7187469 7190471 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 7187469..7190471 Streptomyces avermitilis MA-4680 1211361 NP_827150.1 CDS SAV_5973 NC_003155.4 7190459 7191448 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(7190459..7191448) Streptomyces avermitilis MA-4680 1216454 NP_827151.1 CDS SAV_5974 NC_003155.4 7191520 7192413 D LysR family transcriptional regulator 7191520..7192413 Streptomyces avermitilis MA-4680 1216455 NP_827152.1 CDS SAV_5975 NC_003155.4 7192845 7193720 R hypothetical protein complement(7192845..7193720) Streptomyces avermitilis MA-4680 1216456 NP_827153.1 CDS malR1 NC_003155.4 7193824 7194858 R LacI-family transcriptional regulator; repressor of malE transcription complement(7193824..7194858) Streptomyces avermitilis MA-4680 1211362 NP_827154.1 CDS malE NC_003155.4 7195314 7196585 D ABC transporter substrate-binding protein; maltose-binding protein 7195314..7196585 Streptomyces avermitilis MA-4680 1211363 NP_827155.1 CDS malF NC_003155.4 7196707 7197711 D ABC transporter permease; maltose permease 7196707..7197711 Streptomyces avermitilis MA-4680 1211364 NP_827156.1 CDS malG NC_003155.4 7197731 7198639 D ABC transporter permease; maltose permease 7197731..7198639 Streptomyces avermitilis MA-4680 1211365 NP_827157.1 CDS aglA2 NC_003155.4 7198686 7200536 D alpha-glucosidase 7198686..7200536 Streptomyces avermitilis MA-4680 1211366 NP_827158.1 CDS amyA4 NC_003155.4 7200765 7202147 D alpha-amylase 7200765..7202147 Streptomyces avermitilis MA-4680 1211367 NP_827159.1 CDS amyX NC_003155.4 7202286 7207706 D pullulanase 7202286..7207706 Streptomyces avermitilis MA-4680 1211368 NP_827160.1 CDS prpG2 NC_003155.4 7207777 7209381 D PF00072: Response regulator receiver domain; magnesium or manganese-dependent protein phosphatase 7207777..7209381 Streptomyces avermitilis MA-4680 1216457 NP_827161.1 CDS SAV_5984 NC_003155.4 7209413 7209769 D isomerase 7209413..7209769 Streptomyces avermitilis MA-4680 1216458 NP_827162.1 CDS SAV_5985 NC_003155.4 7209773 7210474 R TetR family transcriptional regulator complement(7209773..7210474) Streptomyces avermitilis MA-4680 1216459 NP_827163.1 CDS SAV_5986 NC_003155.4 7210553 7212469 R hypothetical protein complement(7210553..7212469) Streptomyces avermitilis MA-4680 1216460 NP_827164.1 CDS SAV_5987 NC_003155.4 7212627 7213139 R hypothetical protein complement(7212627..7213139) Streptomyces avermitilis MA-4680 1216461 NP_827165.1 CDS SAV_5988 NC_003155.4 7213196 7216312 R alpha-N-acetylglucosaminidase complement(7213196..7216312) Streptomyces avermitilis MA-4680 1216462 NP_827166.1 CDS SAV_5989 NC_003155.4 7216425 7216892 D lipoprotein 7216425..7216892 Streptomyces avermitilis MA-4680 1216463 NP_827167.1 CDS SAV_5990 NC_003155.4 7216982 7218526 R protein complement(7216982..7218526) Streptomyces avermitilis MA-4680 1216464 NP_827168.1 CDS SAV_5991 NC_003155.4 7218778 7219431 R two-component system response regulator complement(7218778..7219431) Streptomyces avermitilis MA-4680 1216465 NP_827169.1 CDS SAV_5992 NC_003155.4 7219416 7220696 R two-component system sensor kinase complement(7219416..7220696) Streptomyces avermitilis MA-4680 1216466 NP_827170.1 CDS SAV_5993 NC_003155.4 7220796 7221815 R reductase complement(7220796..7221815) Streptomyces avermitilis MA-4680 1216467 NP_827171.1 CDS SAV_5994 NC_003155.4 7221888 7222472 R regulatory protein complement(7221888..7222472) Streptomyces avermitilis MA-4680 1216468 NP_827172.1 CDS SAV_5995 NC_003155.4 7222592 7222801 R hypothetical protein complement(7222592..7222801) Streptomyces avermitilis MA-4680 1216469 NP_827173.1 CDS SAV_5996 NC_003155.4 7222803 7223723 R hypothetical protein complement(7222803..7223723) Streptomyces avermitilis MA-4680 1216470 NP_827174.1 CDS glnA2 NC_003155.4 7223809 7224837 R glutamine synthetase complement(7223809..7224837) Streptomyces avermitilis MA-4680 1211369 NP_827175.1 CDS SAV_5998 NC_003155.4 7225433 7226128 R protein complement(7225433..7226128) Streptomyces avermitilis MA-4680 1216471 NP_827176.1 CDS arsC NC_003155.4 7226254 7226613 R arsenate reductase complement(7226254..7226613) Streptomyces avermitilis MA-4680 1211370 NP_827177.1 CDS SAV_6000 NC_003155.4 7226778 7227086 D hypothetical protein 7226778..7227086 Streptomyces avermitilis MA-4680 1216472 NP_827178.1 CDS SAV_6001 NC_003155.4 7227342 7229018 R PF01636: Phosphotransferase enzyme family; hypothetical protein complement(7227342..7229018) Streptomyces avermitilis MA-4680 1216473 NP_827179.1 CDS SAV_6002 NC_003155.4 7229562 7230203 R hypothetical protein complement(7229562..7230203) Streptomyces avermitilis MA-4680 1216474 NP_827180.1 CDS htpX2 NC_003155.4 7230210 7231142 R putative metalloprotease; heat shock protein HtpX complement(7230210..7231142) Streptomyces avermitilis MA-4680 1211371 NP_827181.1 CDS SAV_6004 NC_003155.4 7231516 7231839 D hypothetical protein 7231516..7231839 Streptomyces avermitilis MA-4680 1216475 NP_827182.1 CDS glnA3 NC_003155.4 7231951 7233360 R glutamine synthetase complement(7231951..7233360) Streptomyces avermitilis MA-4680 1211372 NP_827183.1 CDS SAV_6006 NC_003155.4 7233548 7234039 D PF06271: RDD family; hypothetical protein 7233548..7234039 Streptomyces avermitilis MA-4680 1216476 NP_827184.1 CDS SAV_6007 NC_003155.4 7234237 7234938 R integral membrane protein complement(7234237..7234938) Streptomyces avermitilis MA-4680 1216477 NP_827185.1 CDS SAV_6008 NC_003155.4 7234998 7235195 R hypothetical protein complement(7234998..7235195) Streptomyces avermitilis MA-4680 1216478 NP_827186.1 CDS lipA NC_003155.4 7235472 7236458 R catalyzes the radical-mediated insertion of two sulfur atoms into an ACP ACP bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(7235472..7236458) Streptomyces avermitilis MA-4680 1211373 NP_827187.1 CDS lipB NC_003155.4 7236567 7237364 R lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase complement(7236567..7237364) Streptomyces avermitilis MA-4680 1211374 NP_827188.1 CDS SAV_6011 NC_003155.4 7237623 7239062 D regulatory protein 7237623..7239062 Streptomyces avermitilis MA-4680 1216479 NP_827189.1 CDS SAV_6012 NC_003155.4 7239200 7240597 R PF01593: Flavin containing amine oxidoreductase; oxidoreductase complement(7239200..7240597) Streptomyces avermitilis MA-4680 1216480 NP_827190.1 CDS SAV_6013 NC_003155.4 7240979 7241899 R NAD-dependent epimerase/dehydratase family protein complement(7240979..7241899) Streptomyces avermitilis MA-4680 1216481 NP_827191.1 CDS SAV_6014 NC_003155.4 7241962 7242480 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 7241962..7242480 Streptomyces avermitilis MA-4680 1216482 NP_827192.1 CDS SAV_6015 NC_003155.4 7242475 7243659 R PF00089: Trypsin; serine protease complement(7242475..7243659) Streptomyces avermitilis MA-4680 1216483 NP_827193.1 CDS SAV_6016 NC_003155.4 7243750 7244703 D PF01510: N-acetylmuramoyl-L-alanine amidase; hypothetical protein 7243750..7244703 Streptomyces avermitilis MA-4680 1216484 NP_827194.1 CDS SAV_6017 NC_003155.4 7244790 7245017 D hypothetical protein 7244790..7245017 Streptomyces avermitilis MA-4680 1216485 NP_827195.1 CDS SAV_6018 NC_003155.4 7245052 7245573 R hypothetical protein complement(7245052..7245573) Streptomyces avermitilis MA-4680 1216486 NP_827196.1 CDS SAV_6019 NC_003155.4 7245678 7246649 R DeoR family transcriptional regulator complement(7245678..7246649) Streptomyces avermitilis MA-4680 1216487 NP_827197.1 CDS aceE2 NC_003155.4 7246738 7249440 R paralogs to the E1 component of pyruvate dehydrogenase subunit E1; 2-oxoacid dehydrogenase subunit E1 complement(7246738..7249440) Streptomyces avermitilis MA-4680 1211375 NP_827198.1 CDS SAV_6021 NC_003155.4 7249791 7250414 R GntR family transcriptional regulator complement(7249791..7250414) Streptomyces avermitilis MA-4680 1216488 NP_827199.1 CDS sucB NC_003155.4 7250648 7252471 R dihydrolipoamide S-succinyltransferase complement(7250648..7252471) Streptomyces avermitilis MA-4680 1211376 NP_827200.2 CDS lpdA1 NC_003155.4 7252581 7253969 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(7252581..7253969) Streptomyces avermitilis MA-4680 1211377 NP_827201.1 CDS SAV_6025 NC_003155.4 7254268 7255809 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(7254268..7255809) Streptomyces avermitilis MA-4680 1216489 NP_827202.1 CDS cobS NC_003155.4 7256211 7256993 R cobalamin biosynthesis; cobalamin (5'-phosphate) synthase complement(7256211..7256993) Streptomyces avermitilis MA-4680 1211378 NP_827203.1 CDS SAV_6027 NC_003155.4 7257067 7257831 D PF00499: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; integral membrane protein 7257067..7257831 Streptomyces avermitilis MA-4680 1216490 NP_827204.1 CDS SAV_6028 NC_003155.4 7257812 7258483 R integral membrane protein complement(7257812..7258483) Streptomyces avermitilis MA-4680 1216491 NP_827205.1 CDS SAV_6029 NC_003155.4 7258540 7260474 R PF04329: Family of unknown function (DUF470); integral membrane protein complement(7258540..7260474) Streptomyces avermitilis MA-4680 1216492 NP_827206.1 CDS cobT NC_003155.4 7260693 7261820 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(7260693..7261820) Streptomyces avermitilis MA-4680 1211379 NP_827207.1 CDS SAV_6031 NC_003155.4 7261933 7263144 D hypothetical protein 7261933..7263144 Streptomyces avermitilis MA-4680 1216493 NP_827208.1 CDS cobU NC_003155.4 7263206 7264525 R cobalamin biosynthesis; adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase complement(7263206..7264525) Streptomyces avermitilis MA-4680 1216494 NP_827209.1 CDS SAV_6033 NC_003155.4 7264667 7264891 D hypothetical protein 7264667..7264891 Streptomyces avermitilis MA-4680 1216495 NP_827210.1 CDS SAV_6034 NC_003155.4 7264991 7265704 R methyltransferase complement(7264991..7265704) Streptomyces avermitilis MA-4680 1216496 NP_827211.1 CDS SAV_6035 NC_003155.4 7265788 7266414 R integral membrane protein complement(7265788..7266414) Streptomyces avermitilis MA-4680 1216497 NP_827212.1 CDS SAV_6036 NC_003155.4 7266712 7267482 D phage shock protein A 7266712..7267482 Streptomyces avermitilis MA-4680 1216498 NP_827213.1 CDS SAV_6037 NC_003155.4 7267507 7267785 D hypothetical protein 7267507..7267785 Streptomyces avermitilis MA-4680 1216499 NP_827214.1 CDS SAV_6038 NC_003155.4 7268025 7269245 D two-component system sensor kinase 7268025..7269245 Streptomyces avermitilis MA-4680 1216500 NP_827215.1 CDS SAV_6039 NC_003155.4 7269242 7269925 D two-component system response regulator 7269242..7269925 Streptomyces avermitilis MA-4680 1216501 NP_827216.1 CDS SAV_6040 NC_003155.4 7270082 7273243 D involving efflux of acriflavin-related compounds, PF00873: AcrB/AcrD/AcrF family; cation/multidrug efflux protein 7270082..7273243 Streptomyces avermitilis MA-4680 1216502 NP_827217.1 CDS nadA NC_003155.4 7273374 7274618 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(7273374..7274618) Streptomyces avermitilis MA-4680 1211380 NP_827218.1 CDS SAV_6042 NC_003155.4 7274893 7275249 D PF01521: HesB-like domain; hypothetical protein 7274893..7275249 Streptomyces avermitilis MA-4680 1216503 NP_827219.1 CDS SAV_6043 NC_003155.4 7275456 7276913 R PF04886: PT repeat; hypothetical protein complement(7275456..7276913) Streptomyces avermitilis MA-4680 1216504 NP_827220.1 CDS SAV_6044 NC_003155.4 7277491 7277700 R hypothetical protein complement(7277491..7277700) Streptomyces avermitilis MA-4680 1216505 NP_827221.1 CDS SAV_6045 NC_003155.4 7277792 7278808 D carbohydrate kinase 7277792..7278808 Streptomyces avermitilis MA-4680 1216506 NP_827222.1 CDS SAV_6046 NC_003155.4 7278844 7280226 R aminotransferase complement(7278844..7280226) Streptomyces avermitilis MA-4680 1216507 NP_827223.1 CDS ctaC NC_003155.4 7280555 7281514 D cytochrome c oxidase subunit II 7280555..7281514 Streptomyces avermitilis MA-4680 1211381 NP_827224.1 CDS ctaD1 NC_003155.4 7281511 7283250 D cytochrome c oxidase subunit I 7281511..7283250 Streptomyces avermitilis MA-4680 1211382 NP_827225.1 CDS SAV_6049 NC_003155.4 7283247 7283645 D integral membrane protein 7283247..7283645 Streptomyces avermitilis MA-4680 1216508 NP_827226.1 CDS lppS NC_003155.4 7283820 7285085 D PF03734: ErfK/YbiS/YcfS/YnhG; lipoprotein 7283820..7285085 Streptomyces avermitilis MA-4680 1216509 NP_827227.1 CDS SAV_6051 NC_003155.4 7285142 7285540 R two-component system response regulator complement(7285142..7285540) Streptomyces avermitilis MA-4680 1216510 NP_827228.1 CDS ctaE NC_003155.4 7285719 7286339 D cytochrome c oxidase subunit III 7285719..7286339 Streptomyces avermitilis MA-4680 1211383 NP_827229.1 CDS qcrC NC_003155.4 7286403 7287212 D cytochrome c heme-binding subunit 7286403..7287212 Streptomyces avermitilis MA-4680 1211384 NP_827230.1 CDS qcrA NC_003155.4 7287209 7288282 D ubiquinol-cytochrome c reductase iron-sulphur 'Rieske' subunit 7287209..7288282 Streptomyces avermitilis MA-4680 1211385 NP_827231.1 CDS qcrB1 NC_003155.4 7288279 7289925 D cytochrome b subunit 7288279..7289925 Streptomyces avermitilis MA-4680 1211386 NP_827232.1 CDS trpD NC_003155.4 7290084 7291148 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 7290084..7291148 Streptomyces avermitilis MA-4680 1211387 NP_827233.1 CDS SAV_6057 NC_003155.4 7291526 7292899 D aminotransferase 7291526..7292899 Streptomyces avermitilis MA-4680 1216511 NP_827234.1 CDS SAV_6058 NC_003155.4 7292926 7293207 R transcriptional regulator complement(7292926..7293207) Streptomyces avermitilis MA-4680 1216512 NP_827235.1 CDS SAV_6059 NC_003155.4 7293204 7293947 R PF01694: Rhomboid family; integral membrane protein complement(7293204..7293947) Streptomyces avermitilis MA-4680 1216513 NP_827236.1 CDS SAV_6060 NC_003155.4 7294035 7294313 D hypothetical protein 7294035..7294313 Streptomyces avermitilis MA-4680 1216514 NP_827237.1 CDS SAV_6061 NC_003155.4 7294349 7295698 D PF05991: Protein of unknown function (DUF901); hypothetical protein 7294349..7295698 Streptomyces avermitilis MA-4680 1216515 NP_827238.1 CDS SAV_6062 NC_003155.4 7296036 7297076 D NLP/P60-family protein 7296036..7297076 Streptomyces avermitilis MA-4680 1216516 NP_827239.1 CDS SAV_6063 NC_003155.4 7297300 7298313 D NPL/P60-family protein 7297300..7298313 Streptomyces avermitilis MA-4680 1216517 NP_827240.1 CDS SAV_6064 NC_003155.4 7298336 7299556 D hypothetical protein 7298336..7299556 Streptomyces avermitilis MA-4680 1216518 NP_827241.1 CDS SAV_6065 NC_003155.4 7299741 7301087 D transporter 7299741..7301087 Streptomyces avermitilis MA-4680 1216519 NP_827242.1 CDS SAV_6066 NC_003155.4 7301048 7302280 R hypothetical protein complement(7301048..7302280) Streptomyces avermitilis MA-4680 1216520 NP_827243.1 CDS SAV_6067 NC_003155.4 7302443 7303585 D PF00534: Glycosyl transferases group 1; glycosyl transferase 7302443..7303585 Streptomyces avermitilis MA-4680 1216521 NP_827244.1 CDS SAV_6068 NC_003155.4 7303865 7305499 D PF05199: GMC oxidoreductase; cholesterol oxidase 7303865..7305499 Streptomyces avermitilis MA-4680 1216522 NP_827245.1 CDS fadD14 NC_003155.4 7305519 7307315 R PF00501: AMP-binding enzyme; acyl-CoA synthetase, long-chain fatty acid:CoA ligase complement(7305519..7307315) Streptomyces avermitilis MA-4680 1211388 NP_827246.1 CDS SAV_6070 NC_003155.4 7307611 7308408 D PF00149: Calcineurin-like phosphoesterase; hypothetical protein 7307611..7308408 Streptomyces avermitilis MA-4680 1216523 NP_827247.1 CDS SAV_6071 NC_003155.4 7308543 7308986 D hypothetical protein 7308543..7308986 Streptomyces avermitilis MA-4680 1216524 NP_827248.1 CDS SAV_6072 NC_003155.4 7309096 7310265 D PF02374: Anion-transporting ATPase; ion transporting ATPase 7309096..7310265 Streptomyces avermitilis MA-4680 1216525 NP_827249.1 CDS SAV_6073 NC_003155.4 7310369 7310884 D hypothetical protein 7310369..7310884 Streptomyces avermitilis MA-4680 1216526 NP_827250.1 CDS glkA1 NC_003155.4 7310940 7311893 D glucokinase 7310940..7311893 Streptomyces avermitilis MA-4680 1211389 NP_827251.1 CDS SAV_6075 NC_003155.4 7311988 7312761 D PF03372: Endonuclease/Exonuclease/phosphatase family; hypothetical protein 7311988..7312761 Streptomyces avermitilis MA-4680 1216527 NP_827252.1 CDS SAV_6076 NC_003155.4 7312758 7313819 R hypothetical protein complement(7312758..7313819) Streptomyces avermitilis MA-4680 1216528 NP_827253.1 CDS sig49 NC_003155.4 7313773 7314393 R ECF subfamily RNA polymerase sigma factor complement(7313773..7314393) Streptomyces avermitilis MA-4680 1211390 NP_827254.1 CDS SAV_6078 NC_003155.4 7314664 7315308 R hypothetical protein complement(7314664..7315308) Streptomyces avermitilis MA-4680 1216529 NP_827255.1 CDS SAV_6079 NC_003155.4 7315301 7316218 R esterase/lipase complement(7315301..7316218) Streptomyces avermitilis MA-4680 1216530 NP_827256.1 CDS plsC3 NC_003155.4 7316297 7317079 D 1-acylglycerol-3-phosphate O-acyltransferase 7316297..7317079 Streptomyces avermitilis MA-4680 1211391 NP_827257.1 CDS SAV_6081 NC_003155.4 7317110 7318342 D two-component system sensor kinase 7317110..7318342 Streptomyces avermitilis MA-4680 1216531 NP_827258.1 CDS SAV_6082 NC_003155.4 7318369 7319016 D two-component system response regulator 7318369..7319016 Streptomyces avermitilis MA-4680 1216532 NP_827259.1 CDS pfkA2 NC_003155.4 7319161 7320189 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 7319161..7320189 Streptomyces avermitilis MA-4680 1211392 NP_827260.1 CDS phzE NC_003155.4 7320283 7322268 R anthranilate/para-aminobenzoate synthase component I complement(7320283..7322268) Streptomyces avermitilis MA-4680 1211393 NP_827261.1 CDS SAV_6085 NC_003155.4 7322604 7323869 D hypothetical protein 7322604..7323869 Streptomyces avermitilis MA-4680 1216533 NP_827262.1 CDS aroG NC_003155.4 7323905 7325257 D EC:2.5.1.54, DAHP synthase; 2-dehydro-3-deoxyphosphoheptonate aldolase 7323905..7325257 Streptomyces avermitilis MA-4680 1211394 NP_827263.1 CDS SAV_6087 NC_003155.4 7325434 7325697 D PF04324: BFD-like [2Fe-2S] binding domain; hypothetical protein 7325434..7325697 Streptomyces avermitilis MA-4680 1216534 NP_827264.1 CDS bfrA NC_003155.4 7325739 7326218 R bacterioferritin complement(7325739..7326218) Streptomyces avermitilis MA-4680 1211395 NP_827265.1 CDS SAV_6089 NC_003155.4 7326374 7327006 D PF00174: Oxidoreductase molybdopterin binding domain; hypothetical protein 7326374..7327006 Streptomyces avermitilis MA-4680 1216535 NP_827266.1 CDS SAV_6090 NC_003155.4 7327035 7327631 R hypothetical protein complement(7327035..7327631) Streptomyces avermitilis MA-4680 1216536 NP_827267.1 CDS nfo NC_003155.4 7327680 7328612 R endonuclease IV complement(7327680..7328612) Streptomyces avermitilis MA-4680 1211396 NP_827268.1 CDS pkn28 NC_003155.4 7328671 7330617 R serine/threonine protein kinase complement(7328671..7330617) Streptomyces avermitilis MA-4680 1211397 NP_827269.1 CDS thiG NC_003155.4 7330683 7331477 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(7330683..7331477) Streptomyces avermitilis MA-4680 1211398 NP_827270.1 CDS thiS NC_003155.4 7331481 7331681 R PF02597: ThiS family; thiamine biosynthesis sulfur transfer protein complement(7331481..7331681) Streptomyces avermitilis MA-4680 1216537 NP_827271.1 CDS goxB NC_003155.4 7331678 7332844 R glycine oxidase complement(7331678..7332844) Streptomyces avermitilis MA-4680 1211399 NP_827272.1 CDS SAV_6096 NC_003155.4 7332974 7333357 D hypothetical protein 7332974..7333357 Streptomyces avermitilis MA-4680 1216538 NP_827273.1 CDS fprE NC_003155.4 7333390 7334619 D ferredoxin reductase 7333390..7334619 Streptomyces avermitilis MA-4680 1211400 NP_827274.1 CDS SAV_6098 NC_003155.4 7334766 7335131 D transcriptional regulatory protein 7334766..7335131 Streptomyces avermitilis MA-4680 1216539 NP_827275.1 CDS thiE NC_003155.4 7335277 7335954 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 7335277..7335954 Streptomyces avermitilis MA-4680 1211401 NP_827276.1 CDS metF NC_003155.4 7336079 7337002 D 5,10-methylenetetrahydrofolate reductase 7336079..7337002 Streptomyces avermitilis MA-4680 1211402 NP_827277.1 CDS SAV_6101 NC_003155.4 7337059 7337976 D hypothetical protein 7337059..7337976 Streptomyces avermitilis MA-4680 1216540 NP_827278.1 CDS crtI2 NC_003155.4 7338078 7339571 R phytoene dehydrogenase complement(7338078..7339571) Streptomyces avermitilis MA-4680 1211403 NP_827279.1 CDS SAV_6103 NC_003155.4 7339617 7340270 R hypothetical protein complement(7339617..7340270) Streptomyces avermitilis MA-4680 1216541 NP_827280.1 CDS SAV_6104 NC_003155.4 7340634 7341317 R TetR family transcriptional regulator complement(7340634..7341317) Streptomyces avermitilis MA-4680 1216542 NP_827281.1 CDS SAV_6105 NC_003155.4 7341314 7343398 R PF01061: ABC-2 type transporter; hypothetical protein complement(7341314..7343398) Streptomyces avermitilis MA-4680 1216543 NP_827282.1 CDS SAV_6106 NC_003155.4 7343370 7344392 R ABC transporter ATP-binding protein complement(7343370..7344392) Streptomyces avermitilis MA-4680 1216544 NP_827283.1 CDS SAV_6107 NC_003155.4 7344573 7345121 D hypothetical protein 7344573..7345121 Streptomyces avermitilis MA-4680 1216545 NP_827284.1 CDS SAV_6108 NC_003155.4 7345418 7346188 D methyltransferase 7345418..7346188 Streptomyces avermitilis MA-4680 1216546 NP_827285.1 CDS SAV_6109 NC_003155.4 7346464 7346856 D hypothetical protein 7346464..7346856 Streptomyces avermitilis MA-4680 1216547 NP_827286.1 CDS SAV_6110 NC_003155.4 7347246 7349633 R PF01841: Transglutaminase-like superfamily; hypothetical protein complement(7347246..7349633) Streptomyces avermitilis MA-4680 1216548 NP_827287.1 CDS SAV_6111 NC_003155.4 7349630 7350991 R PF01882: Protein of unknown function DUF58; hypothetical protein complement(7349630..7350991) Streptomyces avermitilis MA-4680 1216549 NP_827288.1 CDS SAV_6112 NC_003155.4 7350988 7352019 R regulatory protein complement(7350988..7352019) Streptomyces avermitilis MA-4680 1216550 NP_827289.1 CDS SAV_6113 NC_003155.4 7352267 7352815 R plant-type carbonic anhydrase complement(7352267..7352815) Streptomyces avermitilis MA-4680 1216551 NP_827290.1 CDS mraW NC_003155.4 7353263 7354219 D S-adenosyl-methyltransferase MraW 7353263..7354219 Streptomyces avermitilis MA-4680 1216552 NP_827291.1 CDS SAV_6115 NC_003155.4 7354230 7354757 D PF04977: Septum formation initiator; hypothetical protein 7354230..7354757 Streptomyces avermitilis MA-4680 1216553 NP_827292.1 CDS ftsI NC_003155.4 7354754 7356715 D PF00905: Penicillin binding protein transpeptidase domain; cell division protein FtsI/penicillin-binding protein 7354754..7356715 Streptomyces avermitilis MA-4680 1211404 NP_827293.1 CDS murE NC_003155.4 7356881 7358401 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 7356881..7358401 Streptomyces avermitilis MA-4680 1211405 NP_827294.1 CDS murF NC_003155.4 7358406 7359821 D UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate-D-alanyl-D-alanine ligase 7358406..7359821 Streptomyces avermitilis MA-4680 1211406 NP_827295.1 CDS mraY NC_003155.4 7359818 7360891 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 7359818..7360891 Streptomyces avermitilis MA-4680 1211407 NP_827296.1 CDS murD NC_003155.4 7360888 7362291 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 7360888..7362291 Streptomyces avermitilis MA-4680 1211408 NP_827297.1 CDS ftsW1 NC_003155.4 7362356 7363705 D PF01098: Cell cycle protein; cell division membrane protein FtsW 7362356..7363705 Streptomyces avermitilis MA-4680 1211409 NP_827298.1 CDS murG NC_003155.4 7363712 7364803 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 7363712..7364803 Streptomyces avermitilis MA-4680 1211410 NP_827299.1 CDS ftsQ NC_003155.4 7365019 7365810 D cell division septal protein FtsQ 7365019..7365810 Streptomyces avermitilis MA-4680 1211411 NP_827300.1 CDS ftsZ NC_003155.4 7366087 7367277 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 7366087..7367277 Streptomyces avermitilis MA-4680 1211412 NP_827301.1 CDS SAV_6125 NC_003155.4 7367274 7368002 D PF02578: Uncharacterised ACR, YfiH family COG1496; hypothetical protein 7367274..7368002 Streptomyces avermitilis MA-4680 1216554 NP_827302.1 CDS SAV_6126 NC_003155.4 7368009 7368728 D PF01168: Alanine racemase, N-terminal domain; hypothetical protein 7368009..7368728 Streptomyces avermitilis MA-4680 1216555 NP_827303.1 CDS SAV_6127 NC_003155.4 7368859 7369500 D PF04472: Protein of unknown function (DUF552); hypothetical protein 7368859..7369500 Streptomyces avermitilis MA-4680 1216556 NP_827304.1 CDS SAV_6128 NC_003155.4 7369552 7369836 D PF02325: YGGT family; hypothetical protein 7369552..7369836 Streptomyces avermitilis MA-4680 1216557 NP_827305.1 CDS SAV_6129 NC_003155.4 7369883 7371109 D PF05103: DivIVA protein; hypothetical protein 7369883..7371109 Streptomyces avermitilis MA-4680 1216558 NP_827306.1 CDS ileS NC_003155.4 7371348 7374491 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(7371348..7374491) Streptomyces avermitilis MA-4680 1211413 NP_827307.1 CDS SAV_6131 NC_003155.4 7375244 7376314 D DNA-binding protein 7375244..7376314 Streptomyces avermitilis MA-4680 1216559 NP_827308.1 CDS lspA NC_003155.4 7376393 7376995 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 7376393..7376995 Streptomyces avermitilis MA-4680 1216560 NP_827309.1 CDS SAV_6133 NC_003155.4 7377080 7378024 D ribosomal large subunit pseudouridine synthase 7377080..7378024 Streptomyces avermitilis MA-4680 1216561 NP_827310.1 CDS SAV_6134 NC_003155.4 7378015 7378506 R hypothetical protein complement(7378015..7378506) Streptomyces avermitilis MA-4680 1216562 NP_827311.1 CDS SAV_6135 NC_003155.4 7378547 7380142 D PF00999: Sodium/hydrogen exchanger family; sodium/proton antiporter 7378547..7380142 Streptomyces avermitilis MA-4680 1216563 NP_827312.1 CDS fabG6 NC_003155.4 7380357 7381097 D PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase 7380357..7381097 Streptomyces avermitilis MA-4680 1211414 NP_827313.1 CDS SAV_6137 NC_003155.4 7381221 7382324 R PF00924: Mechanosensitive ion channel; hypothetical protein complement(7381221..7382324) Streptomyces avermitilis MA-4680 1216564 NP_827314.1 CDS SAV_6138 NC_003155.4 7382444 7383013 D PF01738: Dienelactone hydrolase family; hypothetical protein 7382444..7383013 Streptomyces avermitilis MA-4680 1216565 NP_827315.1 CDS phoD1 NC_003155.4 7383111 7384772 R alkaline phosphatase complement(7383111..7384772) Streptomyces avermitilis MA-4680 1216566 NP_827316.1 CDS SAV_6140 NC_003155.4 7384871 7385710 R PF01323: DSBA-like thioredoxin domain; hypothetical protein complement(7384871..7385710) Streptomyces avermitilis MA-4680 1216567 NP_827317.1 CDS SAV_6141 NC_003155.4 7385777 7386463 R hypothetical protein complement(7385777..7386463) Streptomyces avermitilis MA-4680 1216568 NP_827318.1 CDS SAV_6142 NC_003155.4 7386532 7387857 R hypothetical protein complement(7386532..7387857) Streptomyces avermitilis MA-4680 1216569 NP_827319.1 CDS dnaE NC_003155.4 7388156 7391695 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 7388156..7391695 Streptomyces avermitilis MA-4680 1211415 NP_827320.1 CDS SAV_6144 NC_003155.4 7391829 7392008 R hypothetical protein complement(7391829..7392008) Streptomyces avermitilis MA-4680 1216570 NP_827321.1 CDS SAV_6145 NC_003155.4 7392224 7393450 D PF01936: Protein of unknown function DUF88; hypothetical protein 7392224..7393450 Streptomyces avermitilis MA-4680 1216571 NP_827322.1 CDS SAV_6146 NC_003155.4 7393410 7394549 D ABC transporter ATP-binding protein 7393410..7394549 Streptomyces avermitilis MA-4680 1216572 NP_827323.1 CDS SAV_6147 NC_003155.4 7394581 7395435 D ABC transporter integral membrane transport protein 7394581..7395435 Streptomyces avermitilis MA-4680 1216573 NP_827324.1 CDS SAV_6148 NC_003155.4 7395470 7396135 D hypothetical protein 7395470..7396135 Streptomyces avermitilis MA-4680 1216574 NP_827325.1 CDS SAV_6149 NC_003155.4 7396385 7396885 R transcriptional regulator complement(7396385..7396885) Streptomyces avermitilis MA-4680 1216575 NP_827326.1 CDS SAV_6150 NC_003155.4 7396909 7397649 R PF02190: ATP-dependent protease La (LON) domain; hypothetical protein complement(7396909..7397649) Streptomyces avermitilis MA-4680 1216576 NP_827327.1 CDS SAV_6151 NC_003155.4 7397661 7398749 R hypothetical protein complement(7397661..7398749) Streptomyces avermitilis MA-4680 1216577 NP_827328.1 CDS SAV_6152 NC_003155.4 7398901 7400481 R hypothetical protein complement(7398901..7400481) Streptomyces avermitilis MA-4680 1216578 NP_827329.1 CDS hisD NC_003155.4 7400715 7402040 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 7400715..7402040 Streptomyces avermitilis MA-4680 1211416 NP_827330.1 CDS hisC1 NC_003155.4 7402037 7403146 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 7402037..7403146 Streptomyces avermitilis MA-4680 1211417 NP_827331.1 CDS hisB NC_003155.4 7403143 7403736 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 7403143..7403736 Streptomyces avermitilis MA-4680 1211418 NP_827332.1 CDS SAV_6156 NC_003155.4 7403733 7403897 D hypothetical protein 7403733..7403897 Streptomyces avermitilis MA-4680 1216579 NP_827333.1 CDS hisH NC_003155.4 7403888 7404535 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 7403888..7404535 Streptomyces avermitilis MA-4680 1211419 NP_827334.1 CDS hisA NC_003155.4 7404535 7405263 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 7404535..7405263 Streptomyces avermitilis MA-4680 1211420 NP_827335.1 CDS SAV_6159 NC_003155.4 7405326 7405658 D PF01042: Endoribonuclease L-PSP; hypothetical protein 7405326..7405658 Streptomyces avermitilis MA-4680 1216580 NP_827336.1 CDS hisF NC_003155.4 7405655 7406410 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 7405655..7406410 Streptomyces avermitilis MA-4680 1211421 NP_827337.1 CDS SAV_6161 NC_003155.4 7406528 7407115 D transcription regulator ArsR 7406528..7407115 Streptomyces avermitilis MA-4680 1216581 NP_827338.1 CDS SAV_6162 NC_003155.4 7407247 7408479 D PF07690: Major Facilitator Superfamily; integral membrane efflux protein 7407247..7408479 Streptomyces avermitilis MA-4680 1216582 NP_827339.1 CDS SAV_6163 NC_003155.4 7409008 7410264 D regulatory protein 7409008..7410264 Streptomyces avermitilis MA-4680 1216583 NP_827340.1 CDS SAV_6164 NC_003155.4 7410741 7411832 D branched-chain amino acid ABC transporter ATP-binding protein 7410741..7411832 Streptomyces avermitilis MA-4680 1216584 NP_827341.1 CDS SAV_6165 NC_003155.4 7411829 7412623 D branched-chain amino acid ABC transporter ATP-binding protein 7411829..7412623 Streptomyces avermitilis MA-4680 1216585 NP_827342.1 CDS SAV_6166 NC_003155.4 7412620 7413510 D branched-chain amino acid ABC transporter permease 7412620..7413510 Streptomyces avermitilis MA-4680 1216586 NP_827343.1 CDS SAV_6167 NC_003155.4 7413503 7414684 D branched-chain amino acid ABC transporter permease 7413503..7414684 Streptomyces avermitilis MA-4680 1216587 NP_827344.1 CDS SAV_6168 NC_003155.4 7414681 7415943 D PF01094: Receptor family ligand binding region; lipoprotein 7414681..7415943 Streptomyces avermitilis MA-4680 1216588 NP_827345.1 CDS SAV_6169 NC_003155.4 7416615 7417250 R PF07398: Protein of unknown function (DUF1503); hypothetical protein complement(7416615..7417250) Streptomyces avermitilis MA-4680 1216589 NP_827346.1 CDS hisI NC_003155.4 7417371 7417772 D PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 7417371..7417772 Streptomyces avermitilis MA-4680 1211422 NP_827347.1 CDS trpE NC_003155.4 7417784 7419265 D with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 7417784..7419265 Streptomyces avermitilis MA-4680 1211423 NP_827348.1 CDS SAV_6172 NC_003155.4 7419325 7419969 D hypothetical protein 7419325..7419969 Streptomyces avermitilis MA-4680 1216590 NP_827349.1 CDS SAV_6173 NC_003155.4 7420103 7420342 D hypothetical protein 7420103..7420342 Streptomyces avermitilis MA-4680 1216591 NP_827350.1 CDS SAV_6174 NC_003155.4 7420443 7420931 D hypothetical protein 7420443..7420931 Streptomyces avermitilis MA-4680 1216592 NP_827351.1 CDS trpC NC_003155.4 7421097 7421906 D involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 7421097..7421906 Streptomyces avermitilis MA-4680 1211424 NP_827352.1 CDS SAV_6176 NC_003155.4 7421914 7422222 D hypothetical protein 7421914..7422222 Streptomyces avermitilis MA-4680 1216593 NP_827353.1 CDS trpB NC_003155.4 7422537 7423823 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 7422537..7423823 Streptomyces avermitilis MA-4680 1211425 NP_827354.1 CDS trpA NC_003155.4 7423820 7424653 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 7423820..7424653 Streptomyces avermitilis MA-4680 1211426 NP_827355.1 CDS SAV_6179 NC_003155.4 7424712 7425542 D PF01323: DSBA-like thioredoxin domain; integral membrane protein 7424712..7425542 Streptomyces avermitilis MA-4680 1216594 NP_827356.1 CDS lgt NC_003155.4 7425659 7426681 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 7425659..7426681 Streptomyces avermitilis MA-4680 1211427 NP_827357.1 CDS citE1 NC_003155.4 7426734 7427591 R citrate lyase beta chain complement(7426734..7427591) Streptomyces avermitilis MA-4680 1211428 NP_827358.1 CDS SAV_6182 NC_003155.4 7427588 7428796 R acyl-CoA transferase/carnitine dehydratase complement(7427588..7428796) Streptomyces avermitilis MA-4680 1216595 NP_827359.1 CDS SAV_6183 NC_003155.4 7428930 7430303 R PF03747: ADP-ribosylglycohydrolase; hypothetical protein complement(7428930..7430303) Streptomyces avermitilis MA-4680 1216596 NP_827360.1 CDS SAV_6184 NC_003155.4 7430300 7431496 R PF03747: ADP-ribosylglycohydrolase; hypothetical protein complement(7430300..7431496) Streptomyces avermitilis MA-4680 1216597 NP_827361.1 CDS SAV_6185 NC_003155.4 7431504 7432013 R frameshift; hypothetical protein complement(7431504..7432013) Streptomyces avermitilis MA-4680 1216598 NP_827362.1 CDS SAV_6186 NC_003155.4 7431829 7432746 R frameshift; hypothetical protein complement(7431829..7432746) Streptomyces avermitilis MA-4680 1216599 NP_827363.1 CDS SAV_6187 NC_003155.4 7432743 7434029 R PF03747: ADP-ribosylglycohydrolase; hypothetical protein complement(7432743..7434029) Streptomyces avermitilis MA-4680 1216600 NP_827364.1 CDS SAV_6188 NC_003155.4 7434278 7435009 D PF01988: Integral membrane protein DUF125; hypothetical protein 7434278..7435009 Streptomyces avermitilis MA-4680 1216601 NP_827365.1 CDS gltB NC_003155.4 7435466 7440016 D glutamate synthase(NADPH) large subunit 7435466..7440016 Streptomyces avermitilis MA-4680 1211429 NP_827366.1 CDS gltD NC_003155.4 7440009 7441469 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 7440009..7441469 Streptomyces avermitilis MA-4680 1211430 NP_827367.1 CDS csn2 NC_003155.4 7441635 7442489 R PF01374: Glycosyl hydrolase family 46; chitosanase complement(7441635..7442489) Streptomyces avermitilis MA-4680 1216602 NP_827368.1 CDS SAV_6192 NC_003155.4 7442528 7443493 R PF01694: Rhomboid family; hypothetical protein complement(7442528..7443493) Streptomyces avermitilis MA-4680 1216603 NP_827369.1 CDS SAV_6193 NC_003155.4 7443640 7444359 D toxic cation resistance protein 7443640..7444359 Streptomyces avermitilis MA-4680 1216604 NP_827370.1 CDS SAV_6194 NC_003155.4 7444320 7444934 D PF05962: Bacterial protein of unknown function (DUF886); hypothetical protein 7444320..7444934 Streptomyces avermitilis MA-4680 1216605 NP_827371.1 CDS fadE26 NC_003155.4 7444912 7445871 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(7444912..7445871) Streptomyces avermitilis MA-4680 1211431 NP_827372.1 CDS fadE20 NC_003155.4 7445871 7447010 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(7445871..7447010) Streptomyces avermitilis MA-4680 1211432 NP_827373.1 CDS SAV_6197 NC_003155.4 7447071 7447862 D PF00106: short chain dehydrogenase; short chain dehydrogenase 7447071..7447862 Streptomyces avermitilis MA-4680 1216606 NP_827374.1 CDS SAV_6198 NC_003155.4 7447916 7448530 D TetR family transcriptional regulator 7447916..7448530 Streptomyces avermitilis MA-4680 1216607 NP_827375.1 CDS fadA3 NC_003155.4 7448557 7449714 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 7448557..7449714 Streptomyces avermitilis MA-4680 1211433 NP_827376.1 CDS fabK NC_003155.4 7449753 7450811 R NADH-dependent, FAD-containing enoyl-ACP reductase, PF03060: 2-nitropropane dioxygenase; enoyl-ACP reductase II complement(7449753..7450811) Streptomyces avermitilis MA-4680 1211434 NP_827377.1 CDS cotB NC_003155.4 7450811 7451551 R coenzyme A transferase, subunit B complement(7450811..7451551) Streptomyces avermitilis MA-4680 1216608 NP_827378.1 CDS cotA NC_003155.4 7451548 7452396 R coenzyme A transferase, subunit A complement(7451548..7452396) Streptomyces avermitilis MA-4680 1216609 NP_827379.1 CDS echA13 NC_003155.4 7452393 7453151 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(7452393..7453151) Streptomyces avermitilis MA-4680 1211435 NP_827380.1 CDS SAV_6204 NC_003155.4 7453206 7454036 D PF00106: short chain dehydrogenase; short chain dehydrogenase 7453206..7454036 Streptomyces avermitilis MA-4680 1216610 NP_827381.1 CDS SAV_6205 NC_003155.4 7453994 7454941 D PF00106: short chain dehydrogenase; short chain dehydrogenase 7453994..7454941 Streptomyces avermitilis MA-4680 1216611 NP_827382.1 CDS SAV_6206 NC_003155.4 7455394 7456320 R PF00023: Ankyrin repeat; hypothetical protein complement(7455394..7456320) Streptomyces avermitilis MA-4680 1216612 NP_827383.1 CDS SAV_6207 NC_003155.4 7456432 7457328 R hypothetical protein complement(7456432..7457328) Streptomyces avermitilis MA-4680 1216613 NP_827384.1 CDS SAV_6208 NC_003155.4 7457485 7458360 D trypsinogen precursor 7457485..7458360 Streptomyces avermitilis MA-4680 1216614 NP_827385.1 CDS SAV_6209 NC_003155.4 7458572 7459027 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 7458572..7459027 Streptomyces avermitilis MA-4680 1216615 NP_827386.1 CDS aroH2 NC_003155.4 7459188 7459577 D catalyzes the interconversion of chorismate to prephenate; chorismate mutase 7459188..7459577 Streptomyces avermitilis MA-4680 1216616 NP_827387.1 CDS SAV_6211 NC_003155.4 7459706 7460263 D two-component system response regulator 7459706..7460263 Streptomyces avermitilis MA-4680 1216617 NP_827388.1 CDS SAV_6212 NC_003155.4 7460355 7462895 D PF01433: Peptidase family M1; aminopeptidase 7460355..7462895 Streptomyces avermitilis MA-4680 1216618 NP_827389.1 CDS SAV_6213 NC_003155.4 7463143 7464585 D amino acid decarboxylase 7463143..7464585 Streptomyces avermitilis MA-4680 1216619 NP_827390.1 CDS SAV_6214 NC_003155.4 7464582 7466000 D PF00070: Pyridine nucleotide-disulphide oxidoreductase; monooxygenase 7464582..7466000 Streptomyces avermitilis MA-4680 1216620 NP_827391.1 CDS cpdB NC_003155.4 7466097 7467917 R 2',3'-cyclic-nucleotide 2'-phosphodiesterase complement(7466097..7467917) Streptomyces avermitilis MA-4680 1216621 NP_827392.1 CDS SAV_6216 NC_003155.4 7468007 7468768 D PF04402: Protein of unknown function (DUF541); hypothetical protein 7468007..7468768 Streptomyces avermitilis MA-4680 1216622 NP_827393.1 CDS pykA2 NC_003155.4 7468937 7470373 D pyruvate kinase 7468937..7470373 Streptomyces avermitilis MA-4680 1211436 NP_827394.1 CDS SAV_6218 NC_003155.4 7470385 7471197 R hypothetical protein complement(7470385..7471197) Streptomyces avermitilis MA-4680 1216623 NP_827395.1 CDS SAV_6219 NC_003155.4 7471444 7472100 D two-component system response regulator 7471444..7472100 Streptomyces avermitilis MA-4680 1216624 NP_827396.1 CDS SAV_6220 NC_003155.4 7472204 7472920 R branched-chain amino acid ABC transporter ATP-binding protein complement(7472204..7472920) Streptomyces avermitilis MA-4680 1216625 NP_827397.1 CDS SAV_6221 NC_003155.4 7472917 7473861 R branched-chain amino acid ABC transporter ATP-binding protein complement(7472917..7473861) Streptomyces avermitilis MA-4680 1216626 NP_827398.1 CDS SAV_6222 NC_003155.4 7473858 7475633 R branched-chain amino acid ABC transporter permease complement(7473858..7475633) Streptomyces avermitilis MA-4680 1216627 NP_827399.1 CDS SAV_6223 NC_003155.4 7475639 7476571 R branched-chain amino acid ABC transporter permease complement(7475639..7476571) Streptomyces avermitilis MA-4680 1216628 NP_827400.1 CDS SAV_6224 NC_003155.4 7476683 7477912 R ABC transporter periplasmic component; periplasmic branched-chain amino acid-binding protein complement(7476683..7477912) Streptomyces avermitilis MA-4680 1216629 NP_827401.1 CDS SAV_6225 NC_003155.4 7478832 7479293 R PF03061: Thioesterase superfamily; hypothetical protein complement(7478832..7479293) Streptomyces avermitilis MA-4680 1216630 NP_827402.1 CDS fdhF NC_003155.4 7479360 7481642 R formate dehydrogenase complement(7479360..7481642) Streptomyces avermitilis MA-4680 1211438 NP_827403.1 CDS polA1 NC_003155.4 7481798 7484521 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 7481798..7484521 Streptomyces avermitilis MA-4680 1211439 NP_827404.1 CDS SAV_6228 NC_003155.4 7484789 7486030 R PF04307: Predicted membrane-bound metal-dependent hydrolase (DUF457); hypothetical protein complement(7484789..7486030) Streptomyces avermitilis MA-4680 1216631 NP_827405.1 CDS SAV_6229 NC_003155.4 7486082 7487791 D PF01464: Transglycosylase SLT domain; protein 7486082..7487791 Streptomyces avermitilis MA-4680 1216632 NP_827406.1 CDS SAV_6230 NC_003155.4 7488093 7489085 D hypothetical protein 7488093..7489085 Streptomyces avermitilis MA-4680 1216633 NP_827407.1 CDS SAV_6231 NC_003155.4 7489075 7491708 R PF04408: Helicase associated domain (HA2); ATP-dependent RNA helicase complement(7489075..7491708) Streptomyces avermitilis MA-4680 1216634 NP_827408.1 CDS SAV_6232 NC_003155.4 7491713 7492582 R SAM-dependent methyltransferase complement(7491713..7492582) Streptomyces avermitilis MA-4680 1216635 NP_827409.1 CDS rpsA NC_003155.4 7492899 7494404 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 7492899..7494404 Streptomyces avermitilis MA-4680 1211440 NP_827410.1 CDS SAV_6234 NC_003155.4 7494729 7495667 D PF05601: Protein of unknown function (DUF774); hypothetical protein 7494729..7495667 Streptomyces avermitilis MA-4680 1216636 NP_827411.1 CDS coaE NC_003155.4 7495699 7496340 D dephospho-CoA kinase 7495699..7496340 Streptomyces avermitilis MA-4680 1211441 NP_827412.1 CDS SAV_6236 NC_003155.4 7496391 7496771 D PF00515: TPR Domain; hypothetical protein 7496391..7496771 Streptomyces avermitilis MA-4680 1216637 NP_827413.1 CDS SAV_6237 NC_003155.4 7496817 7497092 R hypothetical protein complement(7496817..7497092) Streptomyces avermitilis MA-4680 1216638 NP_827414.1 CDS SAV_6238 NC_003155.4 7497119 7498156 D hypothetical protein 7497119..7498156 Streptomyces avermitilis MA-4680 1216639 NP_827415.1 CDS SAV_6239 NC_003155.4 7498232 7498915 D hypothetical protein 7498232..7498915 Streptomyces avermitilis MA-4680 1216640 NP_827416.1 CDS SAV_6240 NC_003155.4 7498976 7499518 D PF07681: DoxX; hypothetical protein 7498976..7499518 Streptomyces avermitilis MA-4680 1216641 NP_827417.1 CDS SAV_6241 NC_003155.4 7499778 7500416 R PF01479: S4 domain; hypothetical protein complement(7499778..7500416) Streptomyces avermitilis MA-4680 1216642 NP_827418.1 CDS SAV_6242 NC_003155.4 7500537 7501331 D PF03167: Uracil DNA glycosylase superfamily; hypothetical protein 7500537..7501331 Streptomyces avermitilis MA-4680 1216643 NP_827419.1 CDS SAV_6243 NC_003155.4 7501328 7501735 R hypothetical protein complement(7501328..7501735) Streptomyces avermitilis MA-4680 1216644 NP_827420.1 CDS SAV_6244 NC_003155.4 7501884 7502471 R PF01042: Endoribonuclease L-PSP; hypothetical protein complement(7501884..7502471) Streptomyces avermitilis MA-4680 1216645 NP_827421.1 CDS SAV_6245 NC_003155.4 7502573 7502950 D hypothetical protein 7502573..7502950 Streptomyces avermitilis MA-4680 1216646 NP_827422.1 CDS SAV_6246 NC_003155.4 7503439 7504629 D hypothetical protein 7503439..7504629 Streptomyces avermitilis MA-4680 1216647 NP_827423.1 CDS SAV_6247 NC_003155.4 7504662 7505135 D hypothetical protein 7504662..7505135 Streptomyces avermitilis MA-4680 1216648 NP_827424.1 CDS SAV_6248 NC_003155.4 7506001 7507863 D PF05976: Bacterial membrane protein of unknown function (DUF893); integral membrane protein 7506001..7507863 Streptomyces avermitilis MA-4680 1216649 NP_827425.1 CDS cyp23 NC_003155.4 7508111 7509277 D CYP107X1; cytochrome P450 7508111..7509277 Streptomyces avermitilis MA-4680 1211442 NP_827426.1 CDS SAV_6250 NC_003155.4 7509535 7509708 D hypothetical protein 7509535..7509708 Streptomyces avermitilis MA-4680 1216650 NP_827427.1 CDS SAV_6251 NC_003155.4 7509771 7510226 R hypothetical protein complement(7509771..7510226) Streptomyces avermitilis MA-4680 1216651 NP_827428.1 CDS SAV_6252 NC_003155.4 7510217 7510921 R regulatory protein complement(7510217..7510921) Streptomyces avermitilis MA-4680 1216652 NP_827429.1 CDS SAV_6253 NC_003155.4 7511100 7511960 D DNA-binding protein 7511100..7511960 Streptomyces avermitilis MA-4680 1216653 NP_827430.1 CDS abaA2 NC_003155.4 7511961 7512254 D regulatory protein; AbaA-like protein 7511961..7512254 Streptomyces avermitilis MA-4680 1211443 NP_827431.1 CDS SAV_6255 NC_003155.4 7512494 7513309 D PF04672: Protein of unknown function (DUF574); hypothetical protein 7512494..7513309 Streptomyces avermitilis MA-4680 1216654 NP_827432.1 CDS SAV_6256 NC_003155.4 7513568 7514980 R GntR family transcriptional regulator complement(7513568..7514980) Streptomyces avermitilis MA-4680 1216655 NP_827433.1 CDS SAV_6257 NC_003155.4 7515022 7515537 D PF02627: Carboxymuconolactone decarboxylase family; hypothetical protein 7515022..7515537 Streptomyces avermitilis MA-4680 1216656 NP_827434.1 CDS gltD2 NC_003155.4 7515610 7517100 R function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase complement(7515610..7517100) Streptomyces avermitilis MA-4680 1211444 NP_827435.1 CDS SAV_6259 NC_003155.4 7517288 7517767 R integral membrane protein complement(7517288..7517767) Streptomyces avermitilis MA-4680 1216657 NP_827436.1 CDS SAV_6260 NC_003155.4 7518066 7518884 R PF00643: B-box zinc finger; hypothetical protein complement(7518066..7518884) Streptomyces avermitilis MA-4680 1216658 NP_827437.1 CDS SAV_6261 NC_003155.4 7518944 7519588 D hypothetical protein 7518944..7519588 Streptomyces avermitilis MA-4680 1216659 NP_827438.1 CDS SAV_6262 NC_003155.4 7519576 7520064 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 7519576..7520064 Streptomyces avermitilis MA-4680 1216660 NP_827439.1 CDS SAV_6263 NC_003155.4 7520157 7520630 D PF00571: CBS domain; hypothetical protein 7520157..7520630 Streptomyces avermitilis MA-4680 1216661 NP_827440.1 CDS corA1 NC_003155.4 7520675 7521739 R metal-transport protein complement(7520675..7521739) Streptomyces avermitilis MA-4680 1216662 NP_827441.1 CDS SAV_6265 NC_003155.4 7522014 7522808 D methyltransferase 7522014..7522808 Streptomyces avermitilis MA-4680 1216663 NP_827442.1 CDS SAV_6266 NC_003155.4 7522851 7523795 R sugar kinase complement(7522851..7523795) Streptomyces avermitilis MA-4680 1216664 NP_827443.1 CDS indA NC_003155.4 7523792 7524697 R uncharacterized enzyme involved in pigment biosynthesis, PF04227: Indigoidine synthase A like protein; pigment biosynthetic protein complement(7523792..7524697) Streptomyces avermitilis MA-4680 1216665 NP_827444.1 CDS SAV_6268 NC_003155.4 7524759 7525223 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; dioxygenase 7524759..7525223 Streptomyces avermitilis MA-4680 1216666 NP_827445.1 CDS SAV_6269 NC_003155.4 7525326 7525688 D PF05899: Protein of unknown function (DUF861); hypothetical protein 7525326..7525688 Streptomyces avermitilis MA-4680 1216667 NP_827446.1 CDS ogt3 NC_003155.4 7525710 7526264 R methylated-DNA--protein-cysteine S-methyltransferase complement(7525710..7526264) Streptomyces avermitilis MA-4680 1211445 NP_827447.1 CDS glpQ6 NC_003155.4 7526371 7527243 R glycerophosphoryl diester phosphodiesterase complement(7526371..7527243) Streptomyces avermitilis MA-4680 1216668 NP_827448.1 CDS SAV_6272 NC_003155.4 7527524 7528390 D PF03707: Bacterial signalling protein N terminal repeat; integral membrane protein 7527524..7528390 Streptomyces avermitilis MA-4680 1216669 NP_827449.1 CDS uvrB NC_003155.4 7528431 7530572 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 7528431..7530572 Streptomyces avermitilis MA-4680 1211446 NP_827450.1 CDS SAV_6274 NC_003155.4 7530828 7531406 D PF02342: Bacterial stress protein; export associated protein 7530828..7531406 Streptomyces avermitilis MA-4680 1216670 NP_827451.1 CDS SAV_6275 NC_003155.4 7531487 7533574 D PF02342: Bacterial stress protein; export associated protein 7531487..7533574 Streptomyces avermitilis MA-4680 1216671 NP_827452.1 CDS SAV_6276 NC_003155.4 7533900 7534889 D PF03741: Integral membrane protein TerC family; integral membrane export protein 7533900..7534889 Streptomyces avermitilis MA-4680 1216672 NP_827453.1 CDS chaA NC_003155.4 7535097 7536197 D PF01699: Sodium/calcium exchanger protein; ionic transporter integral membrane protein 7535097..7536197 Streptomyces avermitilis MA-4680 1216673 NP_827454.1 CDS SAV_6278 NC_003155.4 7536257 7537561 R PF00083: Sugar (and other) transporter; transmembrane efflux protein complement(7536257..7537561) Streptomyces avermitilis MA-4680 1216674 NP_827455.1 CDS SAV_6279 NC_003155.4 7537643 7538758 R PF02016: LD-carboxypeptidase; hypothetical protein complement(7537643..7538758) Streptomyces avermitilis MA-4680 1216675 NP_827456.1 CDS aroD NC_003155.4 7538791 7539270 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 7538791..7539270 Streptomyces avermitilis MA-4680 1211447 NP_827457.1 CDS SAV_6281 NC_003155.4 7539316 7540092 R glutamine ABC transporter ATP-binding protein complement(7539316..7540092) Streptomyces avermitilis MA-4680 1216676 NP_827458.1 CDS SAV_6282 NC_003155.4 7540089 7541042 R glutamine ABC transporter permease complement(7540089..7541042) Streptomyces avermitilis MA-4680 1216677 NP_827459.1 CDS SAV_6283 NC_003155.4 7541003 7541941 R amino acid ABC transporter, periplasmic amino acid-binding protein complement(7541003..7541941) Streptomyces avermitilis MA-4680 1216678 NP_827460.1 CDS SAV_6284 NC_003155.4 7542238 7542894 R PF00753: Metallo-beta-lactamase superfamily; Zn-dependent hydrolase complement(7542238..7542894) Streptomyces avermitilis MA-4680 1216679 NP_827461.1 CDS SAV_6285 NC_003155.4 7542905 7543690 R in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol; mycothiol-dependent maleylpyruvate isomerase complement(7542905..7543690) Streptomyces avermitilis MA-4680 1216680 NP_827462.1 CDS uvrA NC_003155.4 7543816 7546845 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 7543816..7546845 Streptomyces avermitilis MA-4680 1211448 NP_827463.1 CDS scrK2 NC_003155.4 7547242 7548153 R fructokinase complement(7547242..7548153) Streptomyces avermitilis MA-4680 1211449 NP_827464.1 CDS SAV_6288 NC_003155.4 7548150 7549199 R LacI family transcriptional regulator complement(7548150..7549199) Streptomyces avermitilis MA-4680 1216681 NP_827465.1 CDS SAV_6289 NC_003155.4 7549417 7549842 D iron sulphur protein 7549417..7549842 Streptomyces avermitilis MA-4680 1216682 NP_827466.1 CDS SAV_6290 NC_003155.4 7549900 7550847 R hypothetical protein complement(7549900..7550847) Streptomyces avermitilis MA-4680 1216683 NP_827467.1 CDS uvrC NC_003155.4 7551262 7553307 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 7551262..7553307 Streptomyces avermitilis MA-4680 1211450 NP_827468.1 CDS SAV_6292 NC_003155.4 7553304 7554317 D PF03668: P-loop ATPase protein family; hypothetical protein 7553304..7554317 Streptomyces avermitilis MA-4680 1216684 NP_827469.1 CDS SAV_6293 NC_003155.4 7554314 7555381 D PF01933: Uncharacterised protein family UPF0052; hypothetical protein 7554314..7555381 Streptomyces avermitilis MA-4680 1216685 NP_827470.1 CDS whiA NC_003155.4 7555372 7556361 D sporulation regulatory protein 7555372..7556361 Streptomyces avermitilis MA-4680 1216686 NP_827471.1 CDS SAV_6295 NC_003155.4 7556529 7559483 D PF00246: Zinc carboxypeptidase; carboxypeptidase 7556529..7559483 Streptomyces avermitilis MA-4680 1216687 NP_827472.1 CDS gap2 NC_003155.4 7559711 7560718 D glyceraldehyde-3-phosphate dehydrogenase 7559711..7560718 Streptomyces avermitilis MA-4680 1211451 NP_827473.1 CDS pgk NC_003155.4 7560846 7562057 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 7560846..7562057 Streptomyces avermitilis MA-4680 1211452 NP_827474.1 CDS tpiA NC_003155.4 7562063 7562839 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 7562063..7562839 Streptomyces avermitilis MA-4680 1211453 NP_827475.1 CDS secG NC_003155.4 7562869 7563207 D PF03840: Preprotein translocase SecG subunit; preprotein translocase subunit SecG 7562869..7563207 Streptomyces avermitilis MA-4680 1211454 NP_827476.1 CDS SAV_6300 NC_003155.4 7563427 7563762 D electron transport protein 7563427..7563762 Streptomyces avermitilis MA-4680 1216688 NP_827477.1 CDS SAV_6301 NC_003155.4 7563791 7565161 D PF07690: Major Facilitator Superfamily; antibiotic transport protein 7563791..7565161 Streptomyces avermitilis MA-4680 1216689 NP_827478.1 CDS pgi NC_003155.4 7565234 7566886 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 7565234..7566886 Streptomyces avermitilis MA-4680 1211455 NP_827479.1 CDS SAV_6303 NC_003155.4 7567065 7569371 R peptide ABC transporter permease complement(7567065..7569371) Streptomyces avermitilis MA-4680 1216690 NP_827480.1 CDS SAV_6304 NC_003155.4 7569642 7570388 R ABC transporter ATP-binding protein complement(7569642..7570388) Streptomyces avermitilis MA-4680 1216691 NP_827481.1 CDS SAV_6305 NC_003155.4 7570385 7570900 R PadR-family transcriptional regulator complement(7570385..7570900) Streptomyces avermitilis MA-4680 1216692 NP_827482.1 CDS SAV_6306 NC_003155.4 7571001 7572329 D ABC transporter substrate-binding protein 7571001..7572329 Streptomyces avermitilis MA-4680 1216693 NP_827483.1 CDS treA NC_003155.4 7572458 7574164 D trehalose-6-phosphate hydrolase 7572458..7574164 Streptomyces avermitilis MA-4680 1211456 NP_827484.1 CDS SAV_6308 NC_003155.4 7574227 7575549 D ABC transporter substrate-binding protein 7574227..7575549 Streptomyces avermitilis MA-4680 1216694 NP_827485.1 CDS SAV_6309 NC_003155.4 7575555 7576913 D ABC transporter permease 7575555..7576913 Streptomyces avermitilis MA-4680 1216695 NP_827486.1 CDS SAV_6310 NC_003155.4 7576910 7577749 D ABC transporter permease 7576910..7577749 Streptomyces avermitilis MA-4680 1216696 NP_827487.1 CDS pgl NC_003155.4 7577825 7578607 R catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase complement(7577825..7578607) Streptomyces avermitilis MA-4680 1211457 NP_827488.1 CDS opcA2 NC_003155.4 7578604 7579725 R oxppcycle protein complement(7578604..7579725) Streptomyces avermitilis MA-4680 1216697 NP_827489.1 CDS zwf2 NC_003155.4 7579722 7581245 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(7579722..7581245) Streptomyces avermitilis MA-4680 1211458 NP_827490.1 CDS tal2 NC_003155.4 7581250 7582368 R catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase complement(7581250..7582368) Streptomyces avermitilis MA-4680 1211459 NP_827491.1 CDS tkt2 NC_003155.4 7582403 7584490 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(7582403..7584490) Streptomyces avermitilis MA-4680 1211460 NP_827492.1 CDS ctaB NC_003155.4 7584999 7585856 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 7584999..7585856 Streptomyces avermitilis MA-4680 1211461 NP_827493.1 CDS SAV_6317 NC_003155.4 7585955 7586311 D hypothetical protein 7585955..7586311 Streptomyces avermitilis MA-4680 1216698 NP_827494.1 CDS SAV_6318 NC_003155.4 7586484 7587590 D PF04909: Amidohydrolase; hypothetical protein 7586484..7587590 Streptomyces avermitilis MA-4680 1216699 NP_827495.1 CDS SAV_6319 NC_003155.4 7587626 7588396 D PF01909: Nucleotidyltransferase domain; hypothetical protein 7587626..7588396 Streptomyces avermitilis MA-4680 1216700 NP_827496.1 CDS ctaA NC_003155.4 7588383 7589438 R PF02628: Cytochrome oxidase assembly protein; cytochrome c oxidase subunit XV assembly protein complement(7588383..7589438) Streptomyces avermitilis MA-4680 1216701 NP_827497.1 CDS SAV_6321 NC_003155.4 7589458 7590228 R ABC transporter permease complement(7589458..7590228) Streptomyces avermitilis MA-4680 1216702 NP_827498.1 CDS SAV_6322 NC_003155.4 7590225 7591157 R ABC transporter ATP-binding protein complement(7590225..7591157) Streptomyces avermitilis MA-4680 1216703 NP_827499.1 CDS SAV_6323 NC_003155.4 7591308 7591499 R hypothetical protein complement(7591308..7591499) Streptomyces avermitilis MA-4680 1216704 NP_827500.1 CDS SAV_6324 NC_003155.4 7591661 7592410 D DNA-binding protein 7591661..7592410 Streptomyces avermitilis MA-4680 1216705 NP_827501.1 CDS sufB NC_003155.4 7592407 7593831 D iron-regulated ABC-type transporter 7592407..7593831 Streptomyces avermitilis MA-4680 1216706 NP_827502.1 CDS SAV_6326 NC_003155.4 7593919 7595100 D iron-regulated ABC-type transporter 7593919..7595100 Streptomyces avermitilis MA-4680 1216707 NP_827503.1 CDS hcaC1 NC_003155.4 7595100 7595420 D PF00355: Rieske [2Fe-2S] domain; ferredoxin subunit of phenylpropionate dioxygenase 7595100..7595420 Streptomyces avermitilis MA-4680 1216708 NP_827504.1 CDS SAV_6328 NC_003155.4 7595428 7596210 D ABC transporter ATP-binding protein 7595428..7596210 Streptomyces avermitilis MA-4680 1216709 NP_827505.1 CDS SAV_6329 NC_003155.4 7596207 7597463 D aminotransferase 7596207..7597463 Streptomyces avermitilis MA-4680 1211462 NP_827506.1 CDS SAV_6330 NC_003155.4 7597480 7597947 D hypothetical protein 7597480..7597947 Streptomyces avermitilis MA-4680 1216710 NP_827507.1 CDS SAV_6331 NC_003155.4 7597944 7598276 D PF01883: Domain of unknown function DUF59; hypothetical protein 7597944..7598276 Streptomyces avermitilis MA-4680 1216711 NP_827508.1 CDS SAV_6332 NC_003155.4 7598377 7599327 R alpha-L-arabinofuranosidase complement(7598377..7599327) Streptomyces avermitilis MA-4680 1216712 NP_827509.1 CDS SAV_6333 NC_003155.4 7599643 7599810 R hypothetical protein complement(7599643..7599810) Streptomyces avermitilis MA-4680 1216713 NP_827510.2 CDS SAV_6335 NC_003155.4 7600087 7601163 R integral membrane protein complement(7600087..7601163) Streptomyces avermitilis MA-4680 1216714 NP_827511.2 CDS emrE NC_003155.4 7601369 7601689 D SMR-type multi-drug efflux transporter 7601369..7601689 Streptomyces avermitilis MA-4680 1216715 NP_827512.1 CDS SAV_6336 NC_003155.4 7601712 7602248 D TetR family transcriptional regulator 7601712..7602248 Streptomyces avermitilis MA-4680 1216716 NP_827513.1 CDS sig50 NC_003155.4 7602496 7603089 D ECF subfamily RNA polymerase sigma factor 7602496..7603089 Streptomyces avermitilis MA-4680 1211463 NP_827514.1 CDS SAV_6338 NC_003155.4 7603092 7604084 D hypothetical protein 7603092..7604084 Streptomyces avermitilis MA-4680 1216717 NP_827515.1 CDS dapD NC_003155.4 7604205 7605194 D 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase 7604205..7605194 Streptomyces avermitilis MA-4680 1211464 NP_827516.1 CDS SAV_6341 NC_003155.4 7606506 7607087 R protein complement(7606506..7607087) Streptomyces avermitilis MA-4680 1216718 NP_827517.1 CDS sig51 NC_003155.4 7607082 7607702 D ECF subfamily RNA polymerase sigma factor 7607082..7607702 Streptomyces avermitilis MA-4680 1211465 NP_827518.1 CDS SAV_6342 NC_003155.4 7607699 7608919 D hypothetical protein 7607699..7608919 Streptomyces avermitilis MA-4680 1216719 NP_827519.1 CDS dapA5 NC_003155.4 7608906 7609853 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(7608906..7609853) Streptomyces avermitilis MA-4680 1211466 NP_827520.1 CDS SAV_6344 NC_003155.4 7609979 7610839 D hypothetical protein 7609979..7610839 Streptomyces avermitilis MA-4680 1216720 NP_827521.1 CDS SAV_6345 NC_003155.4 7610905 7611315 D PF07332: Protein of unknown function (DUF1469); integral membrane protein 7610905..7611315 Streptomyces avermitilis MA-4680 1216721 NP_827522.1 CDS SAV_6346 NC_003155.4 7611312 7612058 D hypothetical protein 7611312..7612058 Streptomyces avermitilis MA-4680 1216722 NP_827523.1 CDS SAV_6347 NC_003155.4 7612276 7614102 R PF03372: Endonuclease/Exonuclease/phosphatase family; large protein complement(7612276..7614102) Streptomyces avermitilis MA-4680 1216723 NP_827524.1 CDS SAV_6348 NC_003155.4 7614461 7615906 D hypothetical protein 7614461..7615906 Streptomyces avermitilis MA-4680 1216724 NP_827525.1 CDS SAV_6349 NC_003155.4 7616478 7617947 D PF05787: Bacterial protein of unknown function (DUF839); protein 7616478..7617947 Streptomyces avermitilis MA-4680 1216725 NP_827526.1 CDS SAV_6350 NC_003155.4 7618443 7620026 D PF05731: TROVE domain; ribonucleoprotein-related protein 7618443..7620026 Streptomyces avermitilis MA-4680 1216726 NP_827527.1 CDS SAV_6351 NC_003155.4 7620108 7621562 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(7620108..7621562) Streptomyces avermitilis MA-4680 1216727 NP_827528.1 CDS SAV_6352 NC_003155.4 7621700 7622305 D TetR family transcriptional regulator 7621700..7622305 Streptomyces avermitilis MA-4680 1216728 NP_827529.1 CDS SAV_6353 NC_003155.4 7622368 7623576 R PF02342: Bacterial stress protein; transport associated protein complement(7622368..7623576) Streptomyces avermitilis MA-4680 1216729 NP_827530.1 CDS SAV_6354 NC_003155.4 7623726 7624715 R PF00107: Zinc-binding dehydrogenase; zinc-binding dehydrogenase complement(7623726..7624715) Streptomyces avermitilis MA-4680 1216730 NP_827531.1 CDS SAV_6355 NC_003155.4 7624712 7625581 R maltose/mannitol transport protein; sugar ABC transporter permease complement(7624712..7625581) Streptomyces avermitilis MA-4680 1216731 NP_827532.1 CDS SAV_6356 NC_003155.4 7625578 7626516 R maltose/mannitol transport protein; sugar ABC transporter permease complement(7625578..7626516) Streptomyces avermitilis MA-4680 1216732 NP_827533.1 CDS SAV_6357 NC_003155.4 7626513 7627883 R maltose/mannitol transport protein; sugar ABC transporter substrate-binding protein complement(7626513..7627883) Streptomyces avermitilis MA-4680 1216733 NP_827534.1 CDS SAV_6358 NC_003155.4 7627994 7628782 R DeoR family transcriptional regulator complement(7627994..7628782) Streptomyces avermitilis MA-4680 1216734 NP_827535.1 CDS SAV_6359 NC_003155.4 7629040 7629849 R PF01370: NAD dependent epimerase/dehydratase family; hypothetical protein complement(7629040..7629849) Streptomyces avermitilis MA-4680 1216735 NP_827536.1 CDS dapA6 NC_003155.4 7630125 7631066 D catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 7630125..7631066 Streptomyces avermitilis MA-4680 1211467 NP_827537.1 CDS SAV_6361 NC_003155.4 7631063 7632295 D alanine-rich protein 7631063..7632295 Streptomyces avermitilis MA-4680 1216736 NP_827538.1 CDS SAV_6362 NC_003155.4 7632199 7633401 R PF07690: Major Facilitator Superfamily; integral membrane efflux protein complement(7632199..7633401) Streptomyces avermitilis MA-4680 1216737 NP_827539.1 CDS SAV_6363 NC_003155.4 7633567 7634157 D hypothetical protein 7633567..7634157 Streptomyces avermitilis MA-4680 1216738 NP_827540.1 CDS SAV_6364 NC_003155.4 7634272 7635024 D PF00753: Metallo-beta-lactamase superfamily; hypothetical protein 7634272..7635024 Streptomyces avermitilis MA-4680 1216739 NP_827541.1 CDS SAV_6365 NC_003155.4 7635144 7635800 D GntR family transcriptional regulator 7635144..7635800 Streptomyces avermitilis MA-4680 1216740 NP_827542.1 CDS dapA7 NC_003155.4 7635797 7636705 D dihydrodipicolinate synthase 7635797..7636705 Streptomyces avermitilis MA-4680 1211468 NP_827543.1 CDS ilvD2 NC_003155.4 7636693 7638432 D catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase 7636693..7638432 Streptomyces avermitilis MA-4680 1211469 NP_827544.1 CDS SAV_6368 NC_003155.4 7638581 7639525 D ABC transporter permease 7638581..7639525 Streptomyces avermitilis MA-4680 1216741 NP_827545.1 CDS SAV_6369 NC_003155.4 7639522 7640424 D ABC transporter permease 7639522..7640424 Streptomyces avermitilis MA-4680 1216742 NP_827546.1 CDS SAV_6370 NC_003155.4 7640520 7641704 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 7640520..7641704 Streptomyces avermitilis MA-4680 1216743 NP_827547.1 CDS SAV_6371 NC_003155.4 7641701 7642567 D hypothetical protein 7641701..7642567 Streptomyces avermitilis MA-4680 1216744 NP_827548.1 CDS SAV_6372 NC_003155.4 7642564 7643874 D xylanase 7642564..7643874 Streptomyces avermitilis MA-4680 1216745 NP_827549.1 CDS SAV_6373 NC_003155.4 7643983 7645320 D PF00497: Bacterial extracellular solute-binding proteins, family 3; sugar-binding protein 7643983..7645320 Streptomyces avermitilis MA-4680 1216746 NP_827550.1 CDS SAV_6374 NC_003155.4 7645485 7646285 D PF00657: GDSL-like Lipase/Acylhydrolase; rhamnogalacturonan acetylesterase 7645485..7646285 Streptomyces avermitilis MA-4680 1216747 NP_827551.1 CDS SAV_6375 NC_003155.4 7646360 7647691 D pectate lyase 7646360..7647691 Streptomyces avermitilis MA-4680 1216748 NP_827552.1 CDS SAV_6376 NC_003155.4 7647694 7648833 D pectinesterase 7647694..7648833 Streptomyces avermitilis MA-4680 1216749 NP_827553.1 CDS SAV_6377 NC_003155.4 7648805 7649860 D pectinesterase 7648805..7649860 Streptomyces avermitilis MA-4680 1216750 NP_827554.1 CDS SAV_6378 NC_003155.4 7649923 7651035 D pectate lyase 7649923..7651035 Streptomyces avermitilis MA-4680 1216751 NP_827555.1 CDS SAV_6379 NC_003155.4 7651127 7651498 R hypothetical protein complement(7651127..7651498) Streptomyces avermitilis MA-4680 1216752 NP_827556.1 CDS SAV_6380 NC_003155.4 7651723 7652517 D acid phosphatase 7651723..7652517 Streptomyces avermitilis MA-4680 1216753 NP_827557.1 CDS xynD NC_003155.4 7652721 7654928 R endo-1,4-beta-xylanase complement(7652721..7654928) Streptomyces avermitilis MA-4680 1211470 NP_827558.1 CDS SAV_6382 NC_003155.4 7655170 7656327 D pectate lyase 7655170..7656327 Streptomyces avermitilis MA-4680 1216754 NP_827559.1 CDS SAV_6383 NC_003155.4 7656496 7657326 R pectate lyase complement(7656496..7657326) Streptomyces avermitilis MA-4680 1216755 NP_827560.1 CDS SAV_6384 NC_003155.4 7657426 7658292 R hypothetical protein complement(7657426..7658292) Streptomyces avermitilis MA-4680 1216756 NP_827561.1 CDS sig52 NC_003155.4 7658289 7658855 R ECF subfamily RNA polymerase sigma factor complement(7658289..7658855) Streptomyces avermitilis MA-4680 1211471 NP_827562.1 CDS pbuG NC_003155.4 7659113 7660564 D hypoxanthine/guanine permease 7659113..7660564 Streptomyces avermitilis MA-4680 1211472 NP_827563.1 CDS pbp11 NC_003155.4 7660632 7662083 R PF00905: Penicillin binding protein transpeptidase domain; penicillin-binding protein complement(7660632..7662083) Streptomyces avermitilis MA-4680 1211473 NP_827564.1 CDS SAV_6388 NC_003155.4 7662205 7662978 R IclR family transcriptional regulator complement(7662205..7662978) Streptomyces avermitilis MA-4680 1216757 NP_827565.1 CDS SAV_6389 NC_003155.4 7663109 7664638 D aldehyde dehydrogenase 7663109..7664638 Streptomyces avermitilis MA-4680 1216758 NP_827566.1 CDS SAV_6390 NC_003155.4 7664785 7665393 D PF07081: Protein of unknown function (DUF1349); hypothetical protein 7664785..7665393 Streptomyces avermitilis MA-4680 1216759 NP_827567.1 CDS SAV_6391 NC_003155.4 7665376 7666779 R PF07690: Major Facilitator Superfamily; drug/proton antiporter complement(7665376..7666779) Streptomyces avermitilis MA-4680 1216760 NP_827568.1 CDS SAV_6392 NC_003155.4 7666842 7667849 D AraC family transcription regulator 7666842..7667849 Streptomyces avermitilis MA-4680 1216761 NP_827569.1 CDS frnE NC_003155.4 7667912 7668628 D PF01323: DSBA-like thioredoxin domain; protein dithiol-disulfide isomerase 7667912..7668628 Streptomyces avermitilis MA-4680 1216762 NP_827570.1 CDS SAV_6394 NC_003155.4 7668699 7669805 D PF00266: Aminotransferase class-V; hypothetical protein 7668699..7669805 Streptomyces avermitilis MA-4680 1216763 NP_827571.1 CDS ectD NC_003155.4 7670236 7671078 R ectoine cluster, PF05721: Phytanoyl-CoA dioxygenase (PhyH); ectoine hydroxylase complement(7670236..7671078) Streptomyces avermitilis MA-4680 1216764 NP_827572.1 CDS ectC NC_003155.4 7671129 7671533 R N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid; L-ectoine synthase complement(7671129..7671533) Streptomyces avermitilis MA-4680 1216765 NP_827573.1 CDS ectB NC_003155.4 7671591 7672862 R catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase complement(7671591..7672862) Streptomyces avermitilis MA-4680 1216766 NP_827574.1 CDS ectA NC_003155.4 7672892 7673431 R ectoine cluster, PF00583: Acetyltransferase (GNAT) family; L-2,4-diaminobutyrate acetyltransferase complement(7672892..7673431) Streptomyces avermitilis MA-4680 1216767 NP_827575.1 CDS aspC2 NC_003155.4 7673797 7674927 R aminotransferase class-V; aspartate aminotransferase complement(7673797..7674927) Streptomyces avermitilis MA-4680 1211474 NP_827576.1 CDS SAV_6400 NC_003155.4 7675117 7675965 D ABC transporter substrate-binding protein 7675117..7675965 Streptomyces avermitilis MA-4680 1216768 NP_827577.1 CDS SAV_6401 NC_003155.4 7675962 7676795 D ABC transporter permease 7675962..7676795 Streptomyces avermitilis MA-4680 1216769 NP_827578.1 CDS SAV_6402 NC_003155.4 7676792 7677595 D ABC transporter ATP-binding protein 7676792..7677595 Streptomyces avermitilis MA-4680 1216770 NP_827579.1 CDS SAV_6403 NC_003155.4 7677606 7678697 D PF01979: Amidohydrolase family; hypothetical protein 7677606..7678697 Streptomyces avermitilis MA-4680 1216771 NP_827580.1 CDS cobC NC_003155.4 7678794 7679774 R cobalamin biosynthesis; hypothetical protein complement(7678794..7679774) Streptomyces avermitilis MA-4680 1216772 NP_827581.1 CDS cbiX NC_003155.4 7679854 7680792 R cobalamin biosynthesis (other possible function is involved in expression of nickel-containing superoxide dismutase); metal binding protein complement(7679854..7680792) Streptomyces avermitilis MA-4680 1211475 NP_827582.1 CDS cobH NC_003155.4 7680789 7681403 R cobalamin biosynthesis; precorrin-8X methylmutase complement(7680789..7681403) Streptomyces avermitilis MA-4680 1211476 NP_827583.1 CDS cobJ NC_003155.4 7681400 7683001 R CbiG/H-fusion; cobalamin biosynthesis; precorrin methylase complement(7681400..7683001) Streptomyces avermitilis MA-4680 1211477 NP_827584.1 CDS cobL1 NC_003155.4 7683079 7684329 R cobalamin biosynthesis; precorrin-6Y C5,15-methyltransferase complement(7683079..7684329) Streptomyces avermitilis MA-4680 1211478 NP_827585.1 CDS cobM NC_003155.4 7684326 7685150 R cobalamin biosynthesis; precorrin-4 C11-methyltransferase complement(7684326..7685150) Streptomyces avermitilis MA-4680 1211479 NP_827586.1 CDS SAV_6410 NC_003155.4 7685255 7685983 D permease 7685255..7685983 Streptomyces avermitilis MA-4680 1216773 NP_827587.1 CDS cobI NC_003155.4 7686007 7686756 R cobalamin biosynthesis; precorrin-2 C20-methyltransferase complement(7686007..7686756) Streptomyces avermitilis MA-4680 1211480 NP_827588.1 CDS cobB NC_003155.4 7686753 7688117 R responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase complement(7686753..7688117) Streptomyces avermitilis MA-4680 1211481 NP_827589.1 CDS cobA NC_003155.4 7688111 7688710 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(7688111..7688710) Streptomyces avermitilis MA-4680 1211482 NP_827590.1 CDS chlI NC_003155.4 7688710 7690779 R cobalamin biosynthesis porphyrin-related; magnesium-chelatase subunit complement(7688710..7690779) Streptomyces avermitilis MA-4680 1216774 NP_827591.1 CDS cobN NC_003155.4 7690776 7694429 R with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN complement(7690776..7694429) Streptomyces avermitilis MA-4680 1211483 NP_827592.1 CDS cobQ1 NC_003155.4 7694426 7695934 R catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase complement(7694426..7695934) Streptomyces avermitilis MA-4680 1211484 NP_827593.1 CDS cobD NC_003155.4 7695931 7696872 R CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein complement(7695931..7696872) Streptomyces avermitilis MA-4680 1211485 NP_827594.1 CDS SAV_6418 NC_003155.4 7697331 7697546 R protein complement(7697331..7697546) Streptomyces avermitilis MA-4680 1216775 NP_827595.1 CDS pitH2 NC_003155.4 7697559 7698812 R low-affinity inorganic phosphate transporter complement(7697559..7698812) Streptomyces avermitilis MA-4680 1216776 NP_827596.1 CDS SAV_6420 NC_003155.4 7699003 7699746 R PF01183: Glycosyl hydrolases family 25; lysozyme precursor complement(7699003..7699746) Streptomyces avermitilis MA-4680 1216777 NP_827597.1 CDS fucA2 NC_003155.4 7699943 7700668 D fuculose-1-phosphate aldolase 7699943..7700668 Streptomyces avermitilis MA-4680 1216778 NP_827598.1 CDS SAV_6422 NC_003155.4 7700865 7701992 D PF00326: Prolyl oligopeptidase family; protein 7700865..7701992 Streptomyces avermitilis MA-4680 1216779 NP_827599.1 CDS SAV_6423 NC_003155.4 7702240 7703607 D hypothetical protein 7702240..7703607 Streptomyces avermitilis MA-4680 1216780 NP_827600.1 CDS SAV_6424 NC_003155.4 7703659 7704081 R PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein complement(7703659..7704081) Streptomyces avermitilis MA-4680 1216781 NP_827601.1 CDS SAV_6425 NC_003155.4 7704121 7705302 D hypothetical protein 7704121..7705302 Streptomyces avermitilis MA-4680 1216782 NP_827602.1 CDS SAV_6426 NC_003155.4 7705394 7706992 D ABC transporter ATP-binding protein 7705394..7706992 Streptomyces avermitilis MA-4680 1216783 NP_827603.1 CDS SAV_6427 NC_003155.4 7707369 7707590 D transcriptional regulator 7707369..7707590 Streptomyces avermitilis MA-4680 1216784 NP_827604.1 CDS echA14 NC_003155.4 7707734 7708567 D enoyl-CoA hydratase/isomerase 7707734..7708567 Streptomyces avermitilis MA-4680 1211486 NP_827605.1 CDS SAV_6429 NC_003155.4 7708564 7709304 R hypothetical protein complement(7708564..7709304) Streptomyces avermitilis MA-4680 1216785 NP_827606.1 CDS SAV_6430 NC_003155.4 7709390 7709872 D PF03780: Protein of unknown function (DUF322); stress-like protein 7709390..7709872 Streptomyces avermitilis MA-4680 1216786 NP_827607.1 CDS SAV_6431 NC_003155.4 7709906 7710091 D hypothetical protein 7709906..7710091 Streptomyces avermitilis MA-4680 1216787 NP_827608.1 CDS SAV_6432 NC_003155.4 7710095 7710496 D PF03780: Protein of unknown function (DUF322); hypothetical protein 7710095..7710496 Streptomyces avermitilis MA-4680 1216788 NP_827609.1 CDS SAV_6433 NC_003155.4 7710493 7711179 D hypothetical protein 7710493..7711179 Streptomyces avermitilis MA-4680 1216789 NP_827610.1 CDS SAV_6434 NC_003155.4 7711176 7711763 D hypothetical protein 7711176..7711763 Streptomyces avermitilis MA-4680 1216790 NP_827611.1 CDS SAV_6435 NC_003155.4 7711830 7712585 R PF00106: short chain dehydrogenase; dehydrogenase complement(7711830..7712585) Streptomyces avermitilis MA-4680 1216791 NP_827612.1 CDS SAV_6436 NC_003155.4 7712591 7714402 R PF00723: Glycosyl hydrolases family 15; glycosyl hydrolase complement(7712591..7714402) Streptomyces avermitilis MA-4680 1216792 NP_827613.1 CDS SAV_6437 NC_003155.4 7714575 7715372 R hypothetical protein complement(7714575..7715372) Streptomyces avermitilis MA-4680 1216793 NP_827614.1 CDS SAV_6438 NC_003155.4 7715441 7715674 R hypothetical protein complement(7715441..7715674) Streptomyces avermitilis MA-4680 1216794 NP_827615.1 CDS dnaQ1 NC_003155.4 7715780 7716757 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(7715780..7716757) Streptomyces avermitilis MA-4680 1211487 NP_827616.1 CDS SAV_6440 NC_003155.4 7716812 7717504 R TetR family transcriptional regulator complement(7716812..7717504) Streptomyces avermitilis MA-4680 1216795 NP_827617.1 CDS SAV_6441 NC_003155.4 7717562 7718359 D PF06314: Acetoacetate decarboxylase (ADC); hypothetical protein 7717562..7718359 Streptomyces avermitilis MA-4680 1216796 NP_827618.1 CDS SAV_6442 NC_003155.4 7718359 7719243 D probable dehydrogenase; hypothetical protein 7718359..7719243 Streptomyces avermitilis MA-4680 1216797 NP_827619.1 CDS SAV_6443 NC_003155.4 7719251 7720567 D PF04909: Amidohydrolase; amidohydrolase 7719251..7720567 Streptomyces avermitilis MA-4680 1216798 NP_827620.1 CDS SAV_6444 NC_003155.4 7720564 7721793 D PF04909: Amidohydrolase; amidohydrolase 7720564..7721793 Streptomyces avermitilis MA-4680 1216799 NP_827621.1 CDS SAV_6445 NC_003155.4 7721818 7722528 D PF01988: Integral membrane protein DUF125; hypothetical protein 7721818..7722528 Streptomyces avermitilis MA-4680 1216800 NP_827622.1 CDS SAV_6446 NC_003155.4 7722672 7723541 D PF01598: Sterol desaturase; sterol desaturase-related protein 7722672..7723541 Streptomyces avermitilis MA-4680 1216801 NP_827623.1 CDS SAV_6447 NC_003155.4 7723538 7724215 D hypothetical protein 7723538..7724215 Streptomyces avermitilis MA-4680 1216802 NP_827624.1 CDS adhA8 NC_003155.4 7724255 7725298 D PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase 7724255..7725298 Streptomyces avermitilis MA-4680 1216803 NP_827625.1 CDS SAV_6449 NC_003155.4 7725302 7726354 R PF05425: Copper resistance protein D; hypothetical protein complement(7725302..7726354) Streptomyces avermitilis MA-4680 1216804 NP_827626.1 CDS SAV_6450 NC_003155.4 7726498 7728009 R PF02515: CoA-transferase family III; hypothetical protein complement(7726498..7728009) Streptomyces avermitilis MA-4680 1216805 NP_827627.1 CDS SAV_6451 NC_003155.4 7728112 7729635 R PF00082: Subtilase family; subtilisin-like protease complement(7728112..7729635) Streptomyces avermitilis MA-4680 1216806 NP_827628.1 CDS SAV_6452 NC_003155.4 7729762 7731297 R PF00082: Subtilase family; subtilisin-like protease complement(7729762..7731297) Streptomyces avermitilis MA-4680 1216807 NP_827629.1 CDS SAV_6453 NC_003155.4 7731675 7732031 D PF04341: Protein of unknown function, DUF485; hypothetical protein 7731675..7732031 Streptomyces avermitilis MA-4680 1216808 NP_827630.1 CDS SAV_6454 NC_003155.4 7732028 7733677 D PF00474: Sodium:solute symporter family; sodium:solute symporter 7732028..7733677 Streptomyces avermitilis MA-4680 1216809 NP_827631.1 CDS moaA NC_003155.4 7733782 7734813 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 7733782..7734813 Streptomyces avermitilis MA-4680 1211488 NP_827632.1 CDS SAV_6456 NC_003155.4 7734841 7735083 R hypothetical protein complement(7734841..7735083) Streptomyces avermitilis MA-4680 1216810 NP_827633.1 CDS SAV_6457 NC_003155.4 7735368 7735847 R hypothetical protein complement(7735368..7735847) Streptomyces avermitilis MA-4680 1216811 NP_827634.1 CDS SAV_6458 NC_003155.4 7736010 7736285 D transglycosylase associated protein 7736010..7736285 Streptomyces avermitilis MA-4680 1216812 NP_827635.1 CDS tyrS NC_003155.4 7736361 7737629 R tyrosyl-tRNA synthetase complement(7736361..7737629) Streptomyces avermitilis MA-4680 1211489 NP_827636.1 CDS SAV_6460 NC_003155.4 7737674 7739068 R PF01523: Putative modulator of DNA gyrase; hypothetical protein complement(7737674..7739068) Streptomyces avermitilis MA-4680 1216813 NP_827637.1 CDS tldD NC_003155.4 7739065 7740588 R PF01523: Putative modulator of DNA gyrase; modulator of DNA gyrase complement(7739065..7740588) Streptomyces avermitilis MA-4680 1216814 NP_827638.1 CDS fabG7 NC_003155.4 7740859 7741578 D PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase 7740859..7741578 Streptomyces avermitilis MA-4680 1211490 NP_827639.1 CDS fabI1 NC_003155.4 7741584 7742351 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 7741584..7742351 Streptomyces avermitilis MA-4680 1211491 NP_827640.1 CDS SAV_6464 NC_003155.4 7742356 7742883 D hypothetical protein 7742356..7742883 Streptomyces avermitilis MA-4680 1216815 NP_827641.1 CDS SAV_6465 NC_003155.4 7742893 7743588 R GntR family transcriptional regulator complement(7742893..7743588) Streptomyces avermitilis MA-4680 1216816 NP_827642.1 CDS SAV_6466 NC_003155.4 7743701 7745041 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 7743701..7745041 Streptomyces avermitilis MA-4680 1216817 NP_827643.1 CDS SAV_6467 NC_003155.4 7745073 7745273 D hypothetical protein 7745073..7745273 Streptomyces avermitilis MA-4680 1216818 NP_827644.1 CDS SAV_6468 NC_003155.4 7745539 7745751 D hypothetical protein 7745539..7745751 Streptomyces avermitilis MA-4680 1216819 NP_827645.1 CDS SAV_6469 NC_003155.4 7745840 7746358 D PF00300: Phosphoglycerate mutase family; hypothetical protein 7745840..7746358 Streptomyces avermitilis MA-4680 1216820 NP_827646.1 CDS serB2 NC_003155.4 7746453 7747667 R 3-phosphoserine phosphatase complement(7746453..7747667) Streptomyces avermitilis MA-4680 1211492 NP_827647.1 CDS SAV_6471 NC_003155.4 7748068 7750083 R hypothetical protein complement(7748068..7750083) Streptomyces avermitilis MA-4680 1216821 NP_827648.1 CDS SAV_6472 NC_003155.4 7750323 7752854 D ABC transporter ATP-binding protein 7750323..7752854 Streptomyces avermitilis MA-4680 1216822 NP_827649.1 CDS SAV_6473 NC_003155.4 7752952 7753695 R PF01464: Transglycosylase SLT domain; hypothetical protein complement(7752952..7753695) Streptomyces avermitilis MA-4680 1216823 NP_827650.1 CDS queA NC_003155.4 7753933 7755165 R S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(7753933..7755165) Streptomyces avermitilis MA-4680 1211493 NP_827651.1 CDS SAV_6475 NC_003155.4 7755174 7755878 R PF00106: short chain dehydrogenase; dehydrogenase complement(7755174..7755878) Streptomyces avermitilis MA-4680 1216824 NP_827652.1 CDS SAV_6476 NC_003155.4 7756067 7757212 D two-component system sensor kinase 7756067..7757212 Streptomyces avermitilis MA-4680 1216825 NP_827653.1 CDS SAV_6477 NC_003155.4 7757205 7757846 D two-component system response regulator 7757205..7757846 Streptomyces avermitilis MA-4680 1216826 NP_827654.1 CDS SAV_6478 NC_003155.4 7758074 7758319 D PF03777: Small domain (DUF320); protein 7758074..7758319 Streptomyces avermitilis MA-4680 1216827 NP_827655.1 CDS SAV_6479 NC_003155.4 7758576 7759364 R hypothetical protein complement(7758576..7759364) Streptomyces avermitilis MA-4680 1216828 NP_827656.1 CDS SAV_6480 NC_003155.4 7759495 7760286 D ABC transporter ATP-binding protein 7759495..7760286 Streptomyces avermitilis MA-4680 1216829 NP_827657.1 CDS SAV_6481 NC_003155.4 7760380 7760811 D hypothetical protein 7760380..7760811 Streptomyces avermitilis MA-4680 1216830 NP_827658.1 CDS SAV_6482 NC_003155.4 7760942 7761892 D PF01145: SPFH domain / Band 7 family; protein 7760942..7761892 Streptomyces avermitilis MA-4680 1216831 NP_827659.1 CDS SAV_6483 NC_003155.4 7761999 7762505 R PF01844: HNH endonuclease; endonuclease complement(7761999..7762505) Streptomyces avermitilis MA-4680 1216832 NP_827660.1 CDS SAV_6484 NC_003155.4 7762650 7763189 R phospholipid-binding protein complement(7762650..7763189) Streptomyces avermitilis MA-4680 1216833 NP_827661.1 CDS SAV_6485 NC_003155.4 7763250 7764035 R PF07070: SpoOM protein; sporulation-control protein complement(7763250..7764035) Streptomyces avermitilis MA-4680 1216834 NP_827662.1 CDS SAV_6486 NC_003155.4 7764232 7764873 D responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 7764232..7764873 Streptomyces avermitilis MA-4680 1216835 NP_827663.1 CDS SAV_6487 NC_003155.4 7770872 7772263 D hypothetical protein 7770872..7772263 Streptomyces avermitilis MA-4680 1216836 NP_827664.1 CDS SAV_6488 NC_003155.4 7772308 7773084 D hypothetical protein 7772308..7773084 Streptomyces avermitilis MA-4680 1216837 NP_827665.1 CDS SAV_6489 NC_003155.4 7773149 7774441 R PF06245: Protein of unknown function (DUF1015); hypothetical protein complement(7773149..7774441) Streptomyces avermitilis MA-4680 1216838 NP_827666.1 CDS SAV_6490 NC_003155.4 7774522 7775550 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 7774522..7775550 Streptomyces avermitilis MA-4680 1216839 NP_827667.1 CDS fepD NC_003155.4 7775720 7776763 D iron-siderophore uptake system transmembrane component; ferrichrome ABC transporter permease 7775720..7776763 Streptomyces avermitilis MA-4680 1216840 NP_827668.1 CDS fepG NC_003155.4 7776760 7777818 D iron-siderophore uptake system transmembrane component; ferrichrome ABC transporter permease 7776760..7777818 Streptomyces avermitilis MA-4680 1211497 NP_827669.1 CDS fepC NC_003155.4 7777815 7778702 D iron-siderophore uptake system transmembrane component; iron-siderophore uptake system ATP-binding protein 7777815..7778702 Streptomyces avermitilis MA-4680 1216841 NP_827670.1 CDS SAV_6494 NC_003155.4 7778912 7779259 R hypothetical protein complement(7778912..7779259) Streptomyces avermitilis MA-4680 1216842 NP_827671.1 CDS SAV_6495 NC_003155.4 7779302 7779607 D hypothetical protein 7779302..7779607 Streptomyces avermitilis MA-4680 1216843 NP_827672.1 CDS SAV_6496 NC_003155.4 7779615 7780430 D PF01479: S4 domain, PF01728: FtsJ-like methyltransferase; rRNA methylase 7779615..7780430 Streptomyces avermitilis MA-4680 1216844 NP_827673.1 CDS ppnK NC_003155.4 7780427 7781332 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 7780427..7781332 Streptomyces avermitilis MA-4680 1216845 NP_827674.1 CDS SAV_6498 NC_003155.4 7781421 7782944 R PF02687: Predicted permease; hypothetical protein complement(7781421..7782944) Streptomyces avermitilis MA-4680 1216846 NP_827675.1 CDS recN NC_003155.4 7782993 7784729 D PF02483: SMC family, C-terminal domain; DNA recombination and repair protein 7782993..7784729 Streptomyces avermitilis MA-4680 1211498 NP_827676.1 CDS SAV_6500 NC_003155.4 7784805 7785704 D hypothetical protein 7784805..7785704 Streptomyces avermitilis MA-4680 1216847 NP_827677.1 CDS SAV_6501 NC_003155.4 7785976 7787148 D PF00534: Glycosyl transferases group 1; glycosyl transferase 7785976..7787148 Streptomyces avermitilis MA-4680 1216848 NP_827678.1 CDS SAV_6502 NC_003155.4 7787170 7788819 R regulatory protein complement(7787170..7788819) Streptomyces avermitilis MA-4680 1216849 NP_827679.1 CDS SAV_6503 NC_003155.4 7788896 7790722 R PF00723: Glycosyl hydrolases family 15; glycosyl hydrolase complement(7788896..7790722) Streptomyces avermitilis MA-4680 1216850 NP_827680.1 CDS pyrG NC_003155.4 7791198 7792847 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 7791198..7792847 Streptomyces avermitilis MA-4680 1211499 NP_827681.1 CDS nudF NC_003155.4 7792863 7793558 D ADP-ribose pyrophosphatase 7792863..7793558 Streptomyces avermitilis MA-4680 1211500 NP_827682.1 CDS SAV_6506 NC_003155.4 7793719 7795800 D regulatory protein 7793719..7795800 Streptomyces avermitilis MA-4680 1216851 NP_827683.1 CDS ald NC_003155.4 7795945 7797060 D L-alanine dehydrogenase 7795945..7797060 Streptomyces avermitilis MA-4680 1211501 NP_827684.1 CDS parA2 NC_003155.4 7797591 7798631 D PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain; partitioning or sporulation protein 7797591..7798631 Streptomyces avermitilis MA-4680 1216852 NP_827685.1 CDS SAV_6509 NC_003155.4 7798616 7799200 D hypothetical protein 7798616..7799200 Streptomyces avermitilis MA-4680 1216853 NP_827686.1 CDS SAV_6510 NC_003155.4 7799763 7800554 D PF02616: Uncharacterised ACR, COG1354; hypothetical protein 7799763..7800554 Streptomyces avermitilis MA-4680 1216854 NP_827687.1 CDS SAV_6511 NC_003155.4 7800551 7801201 D transcriptional regulator 7800551..7801201 Streptomyces avermitilis MA-4680 1216855 NP_827688.1 CDS rluB NC_003155.4 7801201 7802271 D pseudouridine synthase 7801201..7802271 Streptomyces avermitilis MA-4680 1216856 NP_827689.1 CDS SAV_6513 NC_003155.4 7802441 7803202 D PF00293: NUDIX domain; DNA hydrolase 7802441..7803202 Streptomyces avermitilis MA-4680 1216857 NP_827690.1 CDS draG2 NC_003155.4 7803202 7804224 D ADP-ribosylglycohydrolase 7803202..7804224 Streptomyces avermitilis MA-4680 1211502 NP_827691.1 CDS SAV_6515 NC_003155.4 7804228 7804977 D hypothetical protein 7804228..7804977 Streptomyces avermitilis MA-4680 1216858 NP_827692.1 CDS SAV_6516 NC_003155.4 7804903 7805664 R hypothetical protein complement(7804903..7805664) Streptomyces avermitilis MA-4680 1216859 NP_827693.1 CDS SAV_6517 NC_003155.4 7805686 7806150 R iron sulphur protein complement(7805686..7806150) Streptomyces avermitilis MA-4680 1216860 NP_827694.1 CDS SAV_6518 NC_003155.4 7806147 7806731 R hypothetical protein complement(7806147..7806731) Streptomyces avermitilis MA-4680 1216861 NP_827695.1 CDS SAV_6519 NC_003155.4 7806770 7807465 R hypothetical protein complement(7806770..7807465) Streptomyces avermitilis MA-4680 1216862 NP_827696.1 CDS aroH1 NC_003155.4 7807676 7808038 D EC:5.4.99.5; chorismate mutase 7807676..7808038 Streptomyces avermitilis MA-4680 1211503 NP_827697.1 CDS tyrA NC_003155.4 7808035 7809129 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 7808035..7809129 Streptomyces avermitilis MA-4680 1211504 NP_827698.1 CDS cmk NC_003155.4 7809255 7809950 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 7809255..7809950 Streptomyces avermitilis MA-4680 1211505 NP_827699.1 CDS plsC7 NC_003155.4 7809908 7810624 D 1-acylglycerol-3-phosphate O-acyltransferase 7809908..7810624 Streptomyces avermitilis MA-4680 1216863 NP_827700.1 CDS engA NC_003155.4 7810703 7812178 D synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 7810703..7812178 Streptomyces avermitilis MA-4680 1216864 NP_827701.1 CDS SAV_6525 NC_003155.4 7812249 7812638 R hypothetical protein complement(7812249..7812638) Streptomyces avermitilis MA-4680 1216865 NP_827702.1 CDS SAV_6526 NC_003155.4 7812809 7813636 R hypothetical protein complement(7812809..7813636) Streptomyces avermitilis MA-4680 1216866 NP_827703.1 CDS SAV_6527 NC_003155.4 7814121 7814795 D PF06737: Transglycosylase-like domain; peptidoglycan-binding protein 7814121..7814795 Streptomyces avermitilis MA-4680 1216867 NP_827704.1 CDS SAV_6528 NC_003155.4 7814934 7815524 D PF06737: Transglycosylase-like domain; peptidoglycan-binding protein 7814934..7815524 Streptomyces avermitilis MA-4680 1216868 NP_827705.1 CDS SAV_6529 NC_003155.4 7815603 7816253 R ABC transporter ATP-binding protein complement(7815603..7816253) Streptomyces avermitilis MA-4680 1216869 NP_827706.1 CDS SAV_6530 NC_003155.4 7816250 7817059 R ABC transporter ATP-binding protein complement(7816250..7817059) Streptomyces avermitilis MA-4680 1216870 YP_187529.1 CDS SAV_7582 NC_003155.4 7817291 7819186 R ABC transporter permease complement(7817291..7819186) Streptomyces avermitilis MA-4680 3238946 NP_827707.1 CDS SAV_6531 NC_003155.4 7819186 7819668 R hypothetical protein complement(7819186..7819668) Streptomyces avermitilis MA-4680 1216871 NP_827708.1 CDS SAV_6532 NC_003155.4 7819821 7820390 D hypothetical protein 7819821..7820390 Streptomyces avermitilis MA-4680 1216872 NP_827709.1 CDS SAV_6533 NC_003155.4 7820359 7821648 D hypothetical protein 7820359..7821648 Streptomyces avermitilis MA-4680 1216873 NP_827710.1 CDS SAV_6534 NC_003155.4 7821802 7823064 D PF00534: Glycosyl transferases group 1; transferase 7821802..7823064 Streptomyces avermitilis MA-4680 1216874 NP_827711.1 CDS SAV_6535 NC_003155.4 7823061 7823897 D hypothetical protein 7823061..7823897 Streptomyces avermitilis MA-4680 1216875 NP_827712.1 CDS SAV_6536 NC_003155.4 7823967 7825001 D DeoR family transcriptional regulator 7823967..7825001 Streptomyces avermitilis MA-4680 1216876 NP_827713.1 CDS ctaD2 NC_003155.4 7824883 7826574 R EC 1.9.3.1; cytochrome c oxidase subunit I complement(7824883..7826574) Streptomyces avermitilis MA-4680 1216877 NP_827714.1 CDS SAV_6538 NC_003155.4 7827008 7827223 D hypothetical protein 7827008..7827223 Streptomyces avermitilis MA-4680 1216878 NP_827715.1 CDS SAV_6539 NC_003155.4 7827346 7828362 R PF01569: PAP2 superfamily; integral membrane protein complement(7827346..7828362) Streptomyces avermitilis MA-4680 1216879 NP_827716.1 CDS SAV_6540 NC_003155.4 7828601 7829767 R PF04188: Protein of unknown function (DUF409); integral membrane protein complement(7828601..7829767) Streptomyces avermitilis MA-4680 1216880 NP_827717.1 CDS SAV_6541 NC_003155.4 7830029 7831636 D PF07690: Major Facilitator Superfamily; multidrug efflux protein 7830029..7831636 Streptomyces avermitilis MA-4680 1216881 NP_827718.1 CDS fadE12 NC_003155.4 7831763 7832938 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 7831763..7832938 Streptomyces avermitilis MA-4680 1211506 NP_827719.1 CDS SAV_6543 NC_003155.4 7832972 7833409 R PF04472: Protein of unknown function (DUF552); hypothetical protein complement(7832972..7833409) Streptomyces avermitilis MA-4680 1216882 NP_827720.1 CDS SAV_6544 NC_003155.4 7833762 7834910 D regulatory protein 7833762..7834910 Streptomyces avermitilis MA-4680 1216883 NP_827721.1 CDS SAV_6545 NC_003155.4 7834999 7835955 R ABC transporter substrate-binding protein complement(7834999..7835955) Streptomyces avermitilis MA-4680 1216884 NP_827722.1 CDS SAV_6546 NC_003155.4 7836397 7837242 D ABC transporter permease 7836397..7837242 Streptomyces avermitilis MA-4680 1216885 NP_827723.1 CDS SAV_6547 NC_003155.4 7837239 7838999 D hypothetical protein 7837239..7838999 Streptomyces avermitilis MA-4680 1216886 NP_827724.1 CDS SAV_6548 NC_003155.4 7838996 7839784 D ABC transporter ATP-binding protein 7838996..7839784 Streptomyces avermitilis MA-4680 1216887 NP_827725.1 CDS SAV_6549 NC_003155.4 7839800 7840918 D FMNH2-utilizing oxygenase 7839800..7840918 Streptomyces avermitilis MA-4680 1216888 NP_827726.1 CDS SAV_6550 NC_003155.4 7840915 7842300 D FMNH2-utilizing oxygenase 7840915..7842300 Streptomyces avermitilis MA-4680 1216889 NP_827727.1 CDS SAV_6551 NC_003155.4 7842553 7842825 D hypothetical protein 7842553..7842825 Streptomyces avermitilis MA-4680 1216890 NP_827728.1 CDS sprA NC_003155.4 7842932 7844029 D PF02983: Alpha-lytic protease prodomain; serine protease precursor 7842932..7844029 Streptomyces avermitilis MA-4680 1211507 NP_827729.1 CDS sprB NC_003155.4 7844448 7845614 D PF02983: Alpha-lytic protease prodomain; serine protease precursor 7844448..7845614 Streptomyces avermitilis MA-4680 1211508 NP_827730.1 CDS SAV_6554 NC_003155.4 7846297 7846827 D hypothetical protein 7846297..7846827 Streptomyces avermitilis MA-4680 1216891 NP_827731.1 CDS dnaE2 NC_003155.4 7847040 7850525 D DNA polymerase III alpha subunit 7847040..7850525 Streptomyces avermitilis MA-4680 1211509 NP_827732.1 CDS SAV_6556 NC_003155.4 7850522 7851496 D PF00817: impB/mucB/samB family; hypothetical protein 7850522..7851496 Streptomyces avermitilis MA-4680 1216892 NP_827733.1 CDS SAV_6557 NC_003155.4 7851525 7851911 R PF00190: Cupin; hypothetical protein complement(7851525..7851911) Streptomyces avermitilis MA-4680 1216893 NP_827734.1 CDS SAV_6558 NC_003155.4 7851982 7852428 D MarR family transcriptional regulator 7851982..7852428 Streptomyces avermitilis MA-4680 1216894 NP_827735.1 CDS lpsA2 NC_003155.4 7852591 7853451 D lipase 7852591..7853451 Streptomyces avermitilis MA-4680 1216895 NP_827736.1 CDS SAV_6560 NC_003155.4 7853539 7854570 R cellulose-binding protein complement(7853539..7854570) Streptomyces avermitilis MA-4680 1216896 NP_827737.1 CDS SAV_6561 NC_003155.4 7854729 7855199 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 7854729..7855199 Streptomyces avermitilis MA-4680 1216897 NP_827738.1 CDS SAV_6562 NC_003155.4 7855241 7855414 R hypothetical protein complement(7855241..7855414) Streptomyces avermitilis MA-4680 1216898 NP_827739.1 CDS SAV_6563 NC_003155.4 7855489 7856136 D PF01209: ubiE/COQ5 methyltransferase family; hypothetical protein 7855489..7856136 Streptomyces avermitilis MA-4680 1216899 NP_827740.1 CDS SAV_6564 NC_003155.4 7856147 7856665 R PF04167: Protein of unknown function (DUF402); hypothetical protein complement(7856147..7856665) Streptomyces avermitilis MA-4680 1216900 NP_827741.1 CDS SAV_6566 NC_003155.4 7856628 7857656 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(7856628..7857656) Streptomyces avermitilis MA-4680 1216901 NP_827742.1 CDS SAV_6565 NC_003155.4 7857642 7858028 D GntR family transcriptional regulator 7857642..7858028 Streptomyces avermitilis MA-4680 1216902 NP_827743.1 CDS SAV_6567 NC_003155.4 7858065 7858829 R PF01904: Protein of unknown function DUF72; hypothetical protein complement(7858065..7858829) Streptomyces avermitilis MA-4680 1216903 NP_827744.1 CDS SAV_6568 NC_003155.4 7858866 7859960 R PF00004: ATPase family associated with various cellular activities (AAA); ATPase complement(7858866..7859960) Streptomyces avermitilis MA-4680 1216904 NP_827745.1 CDS xynB3 NC_003155.4 7860303 7861568 D xylan 1,4-beta-xylosidase 7860303..7861568 Streptomyces avermitilis MA-4680 1211510 NP_827746.1 CDS SAV_6570 NC_003155.4 7861637 7865329 R PF01554: MatE; hypothetical protein complement(7861637..7865329) Streptomyces avermitilis MA-4680 1216905 NP_827747.1 CDS SAV_6571 NC_003155.4 7865463 7866263 R PF01522: Polysaccharide deacetylase; polysaccharide deacetylase complement(7865463..7866263) Streptomyces avermitilis MA-4680 1216906 NP_827748.1 CDS exoM NC_003155.4 7866260 7867231 R succinoglycan biosynthesis protein complement(7866260..7867231) Streptomyces avermitilis MA-4680 1211511 NP_827749.1 CDS SAV_6573 NC_003155.4 7867252 7868070 R glycosyltransferase complement(7867252..7868070) Streptomyces avermitilis MA-4680 1216907 NP_827750.1 CDS SAV_6574 NC_003155.4 7868446 7869540 R hypothetical protein complement(7868446..7869540) Streptomyces avermitilis MA-4680 1216908 NP_827751.1 CDS SAV_6575 NC_003155.4 7869545 7870036 R hypothetical protein complement(7869545..7870036) Streptomyces avermitilis MA-4680 1216909 NP_827752.1 CDS aprA NC_003155.4 7870143 7871234 R PF00082: Subtilase family; alkaline serine protease complement(7870143..7871234) Streptomyces avermitilis MA-4680 1216910 NP_827753.1 CDS SAV_6577 NC_003155.4 7871666 7872475 D PF00657: GDSL-like Lipase/Acylhydrolase; hydrolase 7871666..7872475 Streptomyces avermitilis MA-4680 1216911 NP_827754.1 CDS pkn29 NC_003155.4 7872510 7874162 R serine/threonine protein kinase complement(7872510..7874162) Streptomyces avermitilis MA-4680 1211512 NP_827755.1 CDS SAV_6579 NC_003155.4 7874190 7875914 R PF03824: High-affinity nickel-transport protein; hypothetical protein complement(7874190..7875914) Streptomyces avermitilis MA-4680 1216912 NP_827756.1 CDS SAV_6580 NC_003155.4 7875911 7877923 R PF00515: TPR Domain; hypothetical protein complement(7875911..7877923) Streptomyces avermitilis MA-4680 1216913 NP_827757.1 CDS SAV_6581 NC_003155.4 7877971 7879491 R hypothetical protein complement(7877971..7879491) Streptomyces avermitilis MA-4680 1216914 NP_827758.1 CDS sig53 NC_003155.4 7879724 7880272 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK 7879724..7880272 Streptomyces avermitilis MA-4680 1211513 NP_827759.1 CDS SAV_6583 NC_003155.4 7880269 7881084 D hypothetical protein 7880269..7881084 Streptomyces avermitilis MA-4680 1216915 NP_827760.1 CDS SAV_6584 NC_003155.4 7881200 7881469 D hypothetical protein 7881200..7881469 Streptomyces avermitilis MA-4680 1216916 NP_827761.1 CDS SAV_6585 NC_003155.4 7881657 7882844 R hypothetical protein complement(7881657..7882844) Streptomyces avermitilis MA-4680 1216917 NP_827762.1 CDS SAV_6586 NC_003155.4 7882893 7883642 R PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator complement(7882893..7883642) Streptomyces avermitilis MA-4680 1216918 NP_827763.1 CDS hmgA NC_003155.4 7883693 7885009 R An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine; homogentisate 1,2-dioxygenase complement(7883693..7885009) Streptomyces avermitilis MA-4680 1211514 NP_827764.1 CDS SAV_6588 NC_003155.4 7885176 7885841 D protein 7885176..7885841 Streptomyces avermitilis MA-4680 1216919 NP_827765.1 CDS SAV_6589 NC_003155.4 7885838 7886458 D TetR family transcriptional regulator 7885838..7886458 Streptomyces avermitilis MA-4680 1216920 NP_827766.1 CDS SAV_6590 NC_003155.4 7886648 7888879 D PF00384: Molybdopterin oxidoreductase; dehydrogenase 7886648..7888879 Streptomyces avermitilis MA-4680 1216921 NP_827767.1 CDS citH NC_003155.4 7889002 7890408 D PF03600: Citrate transporter; divalent metal ions/citrate complex secondary transporter 7889002..7890408 Streptomyces avermitilis MA-4680 1211515 NP_827768.1 CDS SAV_6592 NC_003155.4 7890498 7891658 D PF07690: Major Facilitator Superfamily; integral membrane transport protein 7890498..7891658 Streptomyces avermitilis MA-4680 1216922 NP_827769.1 CDS SAV_6593 NC_003155.4 7891762 7892523 D hypothetical protein 7891762..7892523 Streptomyces avermitilis MA-4680 1216923 NP_827770.1 CDS SAV_6594 NC_003155.4 7892510 7893241 D PF04203: Sortase family; hypothetical protein 7892510..7893241 Streptomyces avermitilis MA-4680 1216924 NP_827771.1 CDS SAV_6595 NC_003155.4 7893453 7894841 D PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase 7893453..7894841 Streptomyces avermitilis MA-4680 1216925 NP_827772.1 CDS adhA9 NC_003155.4 7894856 7895935 D PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase 7894856..7895935 Streptomyces avermitilis MA-4680 1216926 NP_827773.1 CDS SAV_6597 NC_003155.4 7895942 7896952 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(7895942..7896952) Streptomyces avermitilis MA-4680 1216927 NP_827774.1 CDS SAV_6598 NC_003155.4 7897104 7897859 R transcription regulator ArsR complement(7897104..7897859) Streptomyces avermitilis MA-4680 1216928 NP_827775.1 CDS SAV_6599 NC_003155.4 7897953 7898594 R TetR family transcriptional regulator complement(7897953..7898594) Streptomyces avermitilis MA-4680 1216929 NP_827776.1 CDS fadE3 NC_003155.4 7898672 7899823 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 7898672..7899823 Streptomyces avermitilis MA-4680 1211516 NP_827777.1 CDS SAV_6601 NC_003155.4 7899898 7900188 D hypothetical protein 7899898..7900188 Streptomyces avermitilis MA-4680 1216930 NP_827778.1 CDS SAV_6602 NC_003155.4 7900310 7900939 D TetR family transcriptional regulator 7900310..7900939 Streptomyces avermitilis MA-4680 1216931 NP_827779.1 CDS SAV_6603 NC_003155.4 7900986 7901447 R PF01575: MaoC like domain; hypothetical protein complement(7900986..7901447) Streptomyces avermitilis MA-4680 1216932 NP_827780.1 CDS SAV_6604 NC_003155.4 7901555 7902064 D MerR family transcriptional regulator 7901555..7902064 Streptomyces avermitilis MA-4680 1216933 NP_827781.1 CDS SAV_6605 NC_003155.4 7902105 7903172 R PF01588: Putative tRNA binding domain; hypothetical protein complement(7902105..7903172) Streptomyces avermitilis MA-4680 1216934 NP_827782.1 CDS SAV_6606 NC_003155.4 7903707 7904228 D hypothetical protein 7903707..7904228 Streptomyces avermitilis MA-4680 1216935 NP_827783.1 CDS SAV_6607 NC_003155.4 7904314 7904916 R hypothetical protein complement(7904314..7904916) Streptomyces avermitilis MA-4680 1216936 NP_827784.1 CDS pacB3 NC_003155.4 7905201 7907990 D PF01804: Penicillin amidase; penicillin acylase 7905201..7907990 Streptomyces avermitilis MA-4680 1216937 NP_827785.1 CDS SAV_6609 NC_003155.4 7908027 7909388 R PF05990: Protein of unknown function (DUF900); hypothetical protein complement(7908027..7909388) Streptomyces avermitilis MA-4680 1216938 NP_827786.1 CDS SAV_6610 NC_003155.4 7909514 7910833 R PF07075: Protein of unknown function (DUF1343); hypothetical protein complement(7909514..7910833) Streptomyces avermitilis MA-4680 1216939 NP_827787.1 CDS SAV_6611 NC_003155.4 7910967 7911731 D PF00106: short chain dehydrogenase; dehydrogenase 7910967..7911731 Streptomyces avermitilis MA-4680 1216940 NP_827788.1 CDS fadD15 NC_003155.4 7911728 7913395 D PF00501: AMP-binding enzyme; acyl-CoA synthetase, long chain-fatty acid:CoA ligase 7911728..7913395 Streptomyces avermitilis MA-4680 1211517 NP_827789.1 CDS SAV_6613 NC_003155.4 7913414 7914016 D TetR family transcriptional regulator 7913414..7914016 Streptomyces avermitilis MA-4680 1216941 NP_827790.1 CDS fadE17 NC_003155.4 7914103 7915326 R PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase complement(7914103..7915326) Streptomyces avermitilis MA-4680 1211518 NP_827791.1 CDS SAV_6615 NC_003155.4 7915333 7916355 R phosphotransferase complement(7915333..7916355) Streptomyces avermitilis MA-4680 1216942 NP_827792.1 CDS SAV_6616 NC_003155.4 7916537 7917448 R similar to actIV cyclase; polyketide cyclase complement(7916537..7917448) Streptomyces avermitilis MA-4680 1216943 NP_827793.1 CDS SAV_6617 NC_003155.4 7917633 7917956 R hypothetical protein complement(7917633..7917956) Streptomyces avermitilis MA-4680 1216944 NP_827794.1 CDS SAV_6618 NC_003155.4 7917953 7918345 R PF02656: Domain of unknown function DUF; hypothetical protein complement(7917953..7918345) Streptomyces avermitilis MA-4680 1216945 NP_827795.1 CDS SAV_6619 NC_003155.4 7918444 7919046 R PF00293: NUDIX domain; NTP pyrophosphohydrolase complement(7918444..7919046) Streptomyces avermitilis MA-4680 1216946 NP_827796.1 CDS SAV_6620 NC_003155.4 7919083 7920006 R PF05653: Protein of unknown function (DUF803); integral membrane protein complement(7919083..7920006) Streptomyces avermitilis MA-4680 1216947 NP_827797.1 CDS SAV_6621 NC_003155.4 7920188 7921843 D proposed role in polysaccahride synthesis; putative FAD-binding dehydrogenase 7920188..7921843 Streptomyces avermitilis MA-4680 1216948 NP_827798.1 CDS SAV_6622 NC_003155.4 7922313 7923263 D hypothetical protein 7922313..7923263 Streptomyces avermitilis MA-4680 1216949 NP_827799.1 CDS SAV_6623 NC_003155.4 7923378 7924940 D PF00324: Amino acid permease; amino acid permease 7923378..7924940 Streptomyces avermitilis MA-4680 1216950 NP_827800.1 CDS SAV_6624 NC_003155.4 7925239 7925850 D PF00174: Oxidoreductase molybdopterin binding domain; hypothetical protein 7925239..7925850 Streptomyces avermitilis MA-4680 1216951 NP_827801.1 CDS SAV_6625 NC_003155.4 7925834 7926490 D hypothetical protein 7925834..7926490 Streptomyces avermitilis MA-4680 1216952 NP_827802.1 CDS idnD NC_003155.4 7926763 7927788 R PF00107: Zinc-binding dehydrogenase; L-idonate 5-dehydrogenase complement(7926763..7927788) Streptomyces avermitilis MA-4680 1216953 NP_827803.1 CDS kduD NC_003155.4 7927801 7928559 R 5-keto-D-gluconate 5-reductase complement(7927801..7928559) Streptomyces avermitilis MA-4680 1211519 NP_827804.1 CDS gntP NC_003155.4 7928570 7929967 R gluconate permease complement(7928570..7929967) Streptomyces avermitilis MA-4680 1211520 NP_827805.1 CDS gntK2 NC_003155.4 7930069 7930605 R gluconokinase complement(7930069..7930605) Streptomyces avermitilis MA-4680 1211521 NP_827806.1 CDS SAV_6630 NC_003155.4 7930737 7931438 D nrps5 gene cluster; GntR family transcriptional regulator 7930737..7931438 Streptomyces avermitilis MA-4680 1216954 NP_827807.1 CDS SAV_6631 NC_003155.4 7931450 7931872 R nrps5 gene cluster, PF02810: SEC-C motif; hypothetical protein complement(7931450..7931872) Streptomyces avermitilis MA-4680 1216955 NP_827808.1 CDS SAV_6632 NC_003155.4 7931869 7933320 R nrps5 gene cluster, PF01433: Peptidase family M1; metallopeptidase complement(7931869..7933320) Streptomyces avermitilis MA-4680 1216956 NP_827809.1 CDS nrps5 NC_003155.4 7933326 7937201 R nrps5 gene cluster; non-ribosomal peptide synthetase complement(7933326..7937201) Streptomyces avermitilis MA-4680 1216957 NP_827810.1 CDS SAV_6634 NC_003155.4 7937738 7939063 D PF01546: Peptidase family M20/M25/M40; hypothetical protein 7937738..7939063 Streptomyces avermitilis MA-4680 1216958 NP_827811.1 CDS SAV_6635 NC_003155.4 7939230 7939463 D PF03777: Small domain (DUF320); protein 7939230..7939463 Streptomyces avermitilis MA-4680 1216959 NP_827812.1 CDS SAV_6636 NC_003155.4 7939559 7940470 D PF03777: Small domain (DUF320); protein 7939559..7940470 Streptomyces avermitilis MA-4680 1216960 NP_827813.1 CDS SAV_6637 NC_003155.4 7940576 7940764 R hypothetical protein complement(7940576..7940764) Streptomyces avermitilis MA-4680 1216961 NP_827814.1 CDS SAV_6638 NC_003155.4 7940812 7941522 D hypothetical protein 7940812..7941522 Streptomyces avermitilis MA-4680 1216962 NP_827815.1 CDS SAV_6639 NC_003155.4 7941655 7943859 R hypothetical protein complement(7941655..7943859) Streptomyces avermitilis MA-4680 1216963 NP_827816.1 CDS SAV_6640 NC_003155.4 7943952 7944935 R PF00248: Aldo/keto reductase family; oxidoreductase complement(7943952..7944935) Streptomyces avermitilis MA-4680 1216964 NP_827817.1 CDS SAV_6641 NC_003155.4 7945089 7946144 D PF00296: Luciferase-like monooxygenase; FMN-dependent monooxygenase 7945089..7946144 Streptomyces avermitilis MA-4680 1216965 NP_827818.1 CDS SAV_6642 NC_003155.4 7946370 7947158 D hypothetical protein 7946370..7947158 Streptomyces avermitilis MA-4680 1216966 NP_827819.1 CDS corA3 NC_003155.4 7947346 7948377 R PF01544: CorA-like Mg2+ transporter protein; metal-transport protein complement(7947346..7948377) Streptomyces avermitilis MA-4680 1216967 NP_827820.1 CDS SAV_6644 NC_003155.4 7948404 7949126 D PF00300: Phosphoglycerate mutase family; mutase 7948404..7949126 Streptomyces avermitilis MA-4680 1216968 NP_827821.1 CDS SAV_6645 NC_003155.4 7949237 7949827 D hypothetical protein 7949237..7949827 Streptomyces avermitilis MA-4680 1216969 NP_827822.1 CDS SAV_6646 NC_003155.4 7949824 7950609 D hypothetical protein 7949824..7950609 Streptomyces avermitilis MA-4680 1216970 NP_827823.1 CDS cysS NC_003155.4 7950762 7951991 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 7950762..7951991 Streptomyces avermitilis MA-4680 1211523 NP_827824.1 CDS SAV_6648 NC_003155.4 7952094 7952777 R hypothetical protein complement(7952094..7952777) Streptomyces avermitilis MA-4680 1216971 NP_827825.1 CDS SAV_6649 NC_003155.4 7952817 7954775 R PF00082: Subtilase family; serine protease complement(7952817..7954775) Streptomyces avermitilis MA-4680 1216972 NP_827826.1 CDS SAV_6650 NC_003155.4 7955001 7956005 R PF05601: Protein of unknown function (DUF774); hypothetical protein complement(7955001..7956005) Streptomyces avermitilis MA-4680 1216973 NP_827827.1 CDS SAV_6651 NC_003155.4 7956343 7957041 R GntR family transcriptional regulator complement(7956343..7957041) Streptomyces avermitilis MA-4680 1216974 NP_827828.1 CDS SAV_6652 NC_003155.4 7957101 7958399 R PF01979: Amidohydrolase family; N-ethylammeline chlorohydrolase complement(7957101..7958399) Streptomyces avermitilis MA-4680 1216975 NP_827829.1 CDS udp NC_003155.4 7958396 7959184 R uridine phosphorylase complement(7958396..7959184) Streptomyces avermitilis MA-4680 1216976 NP_827830.1 CDS SAV_6654 NC_003155.4 7959181 7960047 R sugar ABC transporter permease complement(7959181..7960047) Streptomyces avermitilis MA-4680 1216977 NP_827831.1 CDS SAV_6655 NC_003155.4 7960047 7961108 R ABC transporter permease complement(7960047..7961108) Streptomyces avermitilis MA-4680 1216978 NP_827832.1 CDS SAV_6656 NC_003155.4 7961110 7962639 R sugar ABC transporter ATP-binding protein complement(7961110..7962639) Streptomyces avermitilis MA-4680 1216979 NP_827833.1 CDS SAV_6657 NC_003155.4 7962620 7963669 R PF02608: Basic membrane protein; lipoprotein complement(7962620..7963669) Streptomyces avermitilis MA-4680 1216980 NP_827834.1 CDS eif2 NC_003155.4 7963968 7965008 D initiation factor eIF-2B alpha subunit 7963968..7965008 Streptomyces avermitilis MA-4680 1211524 NP_827835.1 CDS fucA3 NC_003155.4 7965093 7965701 R fuculose-1-phosphate aldolase complement(7965093..7965701) Streptomyces avermitilis MA-4680 1211525 NP_827836.1 CDS masA NC_003155.4 7965698 7966417 R PF00702: haloacid dehalogenase-like hydrolase; enolase-phosphatase E-1 complement(7965698..7966417) Streptomyces avermitilis MA-4680 1211526 NP_827837.1 CDS SAV_6661 NC_003155.4 7966414 7967007 R oxidase complement(7966414..7967007) Streptomyces avermitilis MA-4680 1216981 NP_827838.1 CDS mtnK NC_003155.4 7967526 7968644 D 5-methylthioribose kinase 7967526..7968644 Streptomyces avermitilis MA-4680 1211527 NP_827839.1 CDS gpd NC_003155.4 7968734 7970350 R glycerol-3-phosphate dehydrogenase complement(7968734..7970350) Streptomyces avermitilis MA-4680 1211528 NP_827840.1 CDS glpK1 NC_003155.4 7970359 7971897 R glycerol kinase complement(7970359..7971897) Streptomyces avermitilis MA-4680 1211529 NP_827841.1 CDS glpF1 NC_003155.4 7972005 7972799 R glycerol uptake facilitator protein complement(7972005..7972799) Streptomyces avermitilis MA-4680 1211530 NP_827842.1 CDS gylR NC_003155.4 7973151 7973915 R glycerol operon regulatory protein complement(7973151..7973915) Streptomyces avermitilis MA-4680 1211531 NP_827843.1 CDS metH NC_003155.4 7974140 7977712 D 5-methyltetrahydrofolate:homocysteine S-methyltransferase 7974140..7977712 Streptomyces avermitilis MA-4680 1211532 NP_827844.1 CDS SAV_6668 NC_003155.4 7977877 7978629 D PF00702: haloacid dehalogenase-like hydrolase; hydrolase 7977877..7978629 Streptomyces avermitilis MA-4680 1216982 NP_827845.1 CDS SAV_6669 NC_003155.4 7979050 7980654 D PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle; lipoprotein oligopeptide binding protein 7979050..7980654 Streptomyces avermitilis MA-4680 1216983 NP_827846.1 CDS SAV_6670 NC_003155.4 7980740 7982323 D PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle; solute binding transport lipoprotein 7980740..7982323 Streptomyces avermitilis MA-4680 1216984 NP_827847.1 CDS SAV_6671 NC_003155.4 7982413 7983084 R two-component system response regulator complement(7982413..7983084) Streptomyces avermitilis MA-4680 1216985 NP_827848.1 CDS SAV_6672 NC_003155.4 7983101 7983961 R hypothetical protein complement(7983101..7983961) Streptomyces avermitilis MA-4680 1216986 NP_827849.1 CDS SAV_6673 NC_003155.4 7984950 7986080 D PF02163: Peptidase family M50; peptidase 7984950..7986080 Streptomyces avermitilis MA-4680 1216987 NP_827850.1 CDS SAV_6674 NC_003155.4 7986121 7987023 D hypothetical protein 7986121..7987023 Streptomyces avermitilis MA-4680 1216988 NP_827851.1 CDS SAV_6675 NC_003155.4 7987213 7987788 D hypothetical protein 7987213..7987788 Streptomyces avermitilis MA-4680 1216989 NP_827852.1 CDS fdxG NC_003155.4 7987868 7988173 R ferredoxin complement(7987868..7988173) Streptomyces avermitilis MA-4680 1211533 NP_827853.1 CDS SAV_6677 NC_003155.4 7988428 7990194 D PF00004: ATPase family associated with various cellular activities (AAA); ATPase AAA 7988428..7990194 Streptomyces avermitilis MA-4680 1216990 NP_827854.1 CDS SAV_6678 NC_003155.4 7990430 7991941 D PF03136: Putative proteasome component; proteasome component 7990430..7991941 Streptomyces avermitilis MA-4680 1216991 NP_827855.1 CDS SAV_6679 NC_003155.4 7992097 7992315 D PF05639: Protein of unknown function (DUF797); hypothetical protein 7992097..7992315 Streptomyces avermitilis MA-4680 1216992 NP_827856.1 CDS SAV_6680 NC_003155.4 7992334 7992942 D endonuclease VII 7992334..7992942 Streptomyces avermitilis MA-4680 1216993 NP_827857.1 CDS prcB1 NC_003155.4 7992894 7993739 D PF00227: Proteasome A-type and B-type; 20S proteasome beta-subunit 7992894..7993739 Streptomyces avermitilis MA-4680 1211534 NP_827858.1 CDS prcA NC_003155.4 7993807 7994568 D PF00227: Proteasome A-type and B-type; 20S proteasome alpha-subunit 7993807..7994568 Streptomyces avermitilis MA-4680 1211535 NP_827859.1 CDS SAV_6683 NC_003155.4 7994625 7995641 R LacI family transcriptional regulator complement(7994625..7995641) Streptomyces avermitilis MA-4680 1216994 NP_827860.1 CDS SAV_6684 NC_003155.4 7995763 7997022 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 7995763..7997022 Streptomyces avermitilis MA-4680 1216995 NP_827861.1 CDS SAV_6685 NC_003155.4 7997032 7998393 D PF03136: Putative proteasome component; proteasome component 7997032..7998393 Streptomyces avermitilis MA-4680 1216996 NP_827862.1 CDS fkbB NC_003155.4 7998523 7999527 D FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 7998523..7999527 Streptomyces avermitilis MA-4680 1211536 NP_827863.1 CDS fkbP NC_003155.4 7999599 7999973 D FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 7999599..7999973 Streptomyces avermitilis MA-4680 1211537 NP_827864.1 CDS SAV_6688 NC_003155.4 8000193 8001170 D hypothetical protein 8000193..8001170 Streptomyces avermitilis MA-4680 1216997 NP_827865.1 CDS SAV_6689 NC_003155.4 8001187 8002227 D hypothetical protein 8001187..8002227 Streptomyces avermitilis MA-4680 1216998 NP_827866.1 CDS SAV_6690 NC_003155.4 8002224 8002604 D hypothetical protein 8002224..8002604 Streptomyces avermitilis MA-4680 1216999 NP_827867.1 CDS SAV_6691 NC_003155.4 8002615 8002809 D hypothetical protein 8002615..8002809 Streptomyces avermitilis MA-4680 1217000 NP_827868.1 CDS tatA NC_003155.4 8003144 8003428 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 8003144..8003428 Streptomyces avermitilis MA-4680 1217001 NP_827869.1 CDS tatC NC_003155.4 8003476 8004423 D PF00902: Sec-independent protein translocase protein (TatC); integral membrane protein 8003476..8004423 Streptomyces avermitilis MA-4680 1217002 NP_827870.1 CDS SAV_6694 NC_003155.4 8004455 8005345 D PF00781: Diacylglycerol kinase catalytic domain (presumed); hypothetical protein 8004455..8005345 Streptomyces avermitilis MA-4680 1217003 NP_827871.1 CDS helY NC_003155.4 8005431 8008244 D PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase 8005431..8008244 Streptomyces avermitilis MA-4680 1211538 NP_827872.1 CDS SAV_6696 NC_003155.4 8008333 8009433 R PF00296: Luciferase-like monooxygenase; monooxygenase complement(8008333..8009433) Streptomyces avermitilis MA-4680 1217004 NP_827873.1 CDS SAV_6697 NC_003155.4 8009625 8011277 R catalyzes the hydrolysis of allophanate; allophanate hydrolase complement(8009625..8011277) Streptomyces avermitilis MA-4680 1217005 NP_827874.1 CDS uahA NC_003155.4 8011294 8014809 R urea amidolyase complement(8011294..8014809) Streptomyces avermitilis MA-4680 1211539 NP_827875.1 CDS SAV_6699 NC_003155.4 8014806 8015441 R hypothetical protein complement(8014806..8015441) Streptomyces avermitilis MA-4680 1217006 NP_827876.1 CDS SAV_6700 NC_003155.4 8015438 8016262 R hypothetical protein complement(8015438..8016262) Streptomyces avermitilis MA-4680 1217007 NP_827877.1 CDS SAV_6701 NC_003155.4 8016448 8017071 D TetR family transcriptional regulator 8016448..8017071 Streptomyces avermitilis MA-4680 1217008 NP_827878.1 CDS cvnA10 NC_003155.4 8017395 8018978 D multi-component regulatory system-10; sensor-like histidine kinase 8017395..8018978 Streptomyces avermitilis MA-4680 1211540 NP_827879.1 CDS cvnB10 NC_003155.4 8018975 8019382 D multi-component regulatory system-10, PF03259: Roadblock/LC7 domain; hypothetical protein 8018975..8019382 Streptomyces avermitilis MA-4680 1211541 NP_827880.1 CDS cvnC10 NC_003155.4 8019379 8019804 D multi-component regulatory system-10, PF05331: Protein of unknown function (DUF742); hypothetical protein 8019379..8019804 Streptomyces avermitilis MA-4680 1211542 NP_827881.1 CDS cvnD10 NC_003155.4 8019785 8020405 D multi-component regulatory system-10; ATP/GTP-binding protein 8019785..8020405 Streptomyces avermitilis MA-4680 1211543 NP_827882.1 CDS cyp24 NC_003155.4 8020473 8021933 D CYP157C2, adjacent to multi-component regulatory system-10; cytochrome P450 8020473..8021933 Streptomyces avermitilis MA-4680 1211544 NP_827883.1 CDS SAV_6707 NC_003155.4 8022004 8022969 R ribosomal pseudouridine synthase complement(8022004..8022969) Streptomyces avermitilis MA-4680 1217009 NP_827884.1 CDS SAV_6708 NC_003155.4 8023104 8023706 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8023104..8023706 Streptomyces avermitilis MA-4680 1217010 NP_827885.1 CDS SAV_6709 NC_003155.4 8023722 8025302 R amino acid permease complement(8023722..8025302) Streptomyces avermitilis MA-4680 1217011 NP_827886.1 CDS SAV_6710 NC_003155.4 8025589 8026236 D ankyrin-like protein 8025589..8026236 Streptomyces avermitilis MA-4680 1217012 NP_827887.1 CDS SAV_6711 NC_003155.4 8026486 8027517 D ABC transporter ATP-binding protein 8026486..8027517 Streptomyces avermitilis MA-4680 1217013 NP_827888.1 CDS SAV_6712 NC_003155.4 8027514 8028290 D multidrug ABC transporter permease 8027514..8028290 Streptomyces avermitilis MA-4680 1217014 NP_827889.1 CDS SAV_6713 NC_003155.4 8028311 8029159 R PF04954: Siderophore-interacting protein; siderophore-interacting protein complement(8028311..8029159) Streptomyces avermitilis MA-4680 1217015 NP_827890.1 CDS SAV_6714 NC_003155.4 8029222 8030151 R 5'-3' exonuclease complement(8029222..8030151) Streptomyces avermitilis MA-4680 1217016 NP_827891.1 CDS opuAA NC_003155.4 8030365 8031444 D glycine/betaine ABC transporter ATP-binding protein 8030365..8031444 Streptomyces avermitilis MA-4680 1211545 NP_827892.1 CDS opuABC NC_003155.4 8031437 8034052 D glycine/betaine ABC transporter permease 8031437..8034052 Streptomyces avermitilis MA-4680 1211546 NP_827893.1 CDS SAV_6717 NC_003155.4 8034155 8034835 D hypothetical protein 8034155..8034835 Streptomyces avermitilis MA-4680 1217017 NP_827894.1 CDS SAV_6718 NC_003155.4 8035015 8035590 D regulatory protein 8035015..8035590 Streptomyces avermitilis MA-4680 1217018 NP_827895.1 CDS SAV_6719 NC_003155.4 8035685 8036482 D methyltransferase 8035685..8036482 Streptomyces avermitilis MA-4680 1217019 NP_827896.1 CDS SAV_6720 NC_003155.4 8036490 8037245 D PF01497: Periplasmic binding protein; hypothetical protein 8036490..8037245 Streptomyces avermitilis MA-4680 1217020 NP_827897.1 CDS SAV_6721 NC_003155.4 8037211 8038371 R PF03595: C4-dicarboxylate transporter/malic acid transport protein; integral membrane protein complement(8037211..8038371) Streptomyces avermitilis MA-4680 1217021 NP_827898.1 CDS SAV_6722 NC_003155.4 8038442 8039362 D LysR family transcriptional regulator 8038442..8039362 Streptomyces avermitilis MA-4680 1217022 NP_827899.1 CDS SAV_6723 NC_003155.4 8039394 8040179 R PF00117: Glutamine amidotransferase class-I; hypothetical protein complement(8039394..8040179) Streptomyces avermitilis MA-4680 1217023 NP_827900.1 CDS SAV_6724 NC_003155.4 8040205 8040981 R GntR family transcriptional regulator complement(8040205..8040981) Streptomyces avermitilis MA-4680 1217024 NP_827901.1 CDS glnA4 NC_003155.4 8041036 8042400 D glutamine synthetase 8041036..8042400 Streptomyces avermitilis MA-4680 1211547 NP_827902.1 CDS feaB NC_003155.4 8042397 8043788 D phenylacetaldehyde dehydrogenase 8042397..8043788 Streptomyces avermitilis MA-4680 1217025 NP_827903.1 CDS SAV_6727 NC_003155.4 8043785 8044576 D PF00106: short chain dehydrogenase; short chain dehydrogenase 8043785..8044576 Streptomyces avermitilis MA-4680 1217026 NP_827904.1 CDS SAV_6728 NC_003155.4 8044652 8045866 D lipoprotein 8044652..8045866 Streptomyces avermitilis MA-4680 1217027 NP_827905.1 CDS SAV_6729 NC_003155.4 8045901 8046833 D hypothetical protein 8045901..8046833 Streptomyces avermitilis MA-4680 1217028 NP_827906.1 CDS SAV_6730 NC_003155.4 8046949 8048151 R PF01168: Alanine racemase, N-terminal domain; hypothetical protein complement(8046949..8048151) Streptomyces avermitilis MA-4680 1217029 NP_827907.1 CDS SAV_6731 NC_003155.4 8048174 8049283 R hypothetical protein complement(8048174..8049283) Streptomyces avermitilis MA-4680 1217030 NP_827908.1 CDS SAV_6732 NC_003155.4 8049489 8050241 D hypothetical protein 8049489..8050241 Streptomyces avermitilis MA-4680 1217031 NP_827909.1 CDS SAV_6733 NC_003155.4 8050238 8051458 D PF00082: Subtilase family; serine protease 8050238..8051458 Streptomyces avermitilis MA-4680 1217032 NP_827910.1 CDS SAV_6734 NC_003155.4 8051504 8052454 R protein complement(8051504..8052454) Streptomyces avermitilis MA-4680 1217033 NP_827911.1 CDS SAV_6735 NC_003155.4 8052605 8053336 D hypothetical protein 8052605..8053336 Streptomyces avermitilis MA-4680 1217034 NP_827912.1 CDS SAV_6736 NC_003155.4 8053489 8053845 R hypothetical protein complement(8053489..8053845) Streptomyces avermitilis MA-4680 1217035 NP_827913.1 CDS infC NC_003155.4 8054233 8054958 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 8054233..8054958 Streptomyces avermitilis MA-4680 1211548 NP_827914.1 CDS rpmI NC_003155.4 8055065 8055259 D 50S ribosomal protein L35 8055065..8055259 Streptomyces avermitilis MA-4680 1211549 NP_827915.1 CDS rplT NC_003155.4 8055355 8055738 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 8055355..8055738 Streptomyces avermitilis MA-4680 1211550 NP_827916.1 CDS tsnR2 NC_003155.4 8055796 8056722 D PF00588: SpoU rRNA Methylase family; rRNA methyltransferase 8055796..8056722 Streptomyces avermitilis MA-4680 1217036 NP_827917.1 CDS SAV_6741 NC_003155.4 8056816 8057979 D two-component system sensor kinase 8056816..8057979 Streptomyces avermitilis MA-4680 1217037 NP_827918.1 CDS pheS NC_003155.4 8058206 8059288 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 8058206..8059288 Streptomyces avermitilis MA-4680 1211551 NP_827919.1 CDS pheT NC_003155.4 8059288 8061789 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 8059288..8061789 Streptomyces avermitilis MA-4680 1211552 NP_827920.1 CDS prpB12 NC_003155.4 8062098 8063252 D PF02673: Bacitracin resistance protein BacA; magnesium or manganese-dependent protein phosphatase 8062098..8063252 Streptomyces avermitilis MA-4680 1217038 NP_827921.1 CDS SAV_6745 NC_003155.4 8063589 8064929 D PF06036: Streptomyces protein of unknown function (DUF921); transcriptional regulator 8063589..8064929 Streptomyces avermitilis MA-4680 1217039 NP_827922.1 CDS SAV_6746 NC_003155.4 8065084 8065629 D PF00293: NUDIX domain; hypothetical protein 8065084..8065629 Streptomyces avermitilis MA-4680 1217040 NP_827923.1 CDS SAV_6747 NC_003155.4 8065650 8065961 R hypothetical protein complement(8065650..8065961) Streptomyces avermitilis MA-4680 1217041 NP_827924.1 CDS fadC5 NC_003155.4 8066129 8067010 R converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase complement(8066129..8067010) Streptomyces avermitilis MA-4680 1211553 NP_827925.1 CDS SAV_6749 NC_003155.4 8067170 8068423 D PF02638: Uncharacterized BCR, COG1649; protein 8067170..8068423 Streptomyces avermitilis MA-4680 1217042 NP_827926.1 CDS SAV_6750 NC_003155.4 8068425 8068625 R hypothetical protein complement(8068425..8068625) Streptomyces avermitilis MA-4680 1217043 NP_827927.1 CDS SAV_6751 NC_003155.4 8068730 8069749 R PF00892: Integral membrane protein DUF6; integral membrane protein complement(8068730..8069749) Streptomyces avermitilis MA-4680 1217044 NP_827928.1 CDS SAV_6752 NC_003155.4 8069871 8071181 D transcriptional regulator 8069871..8071181 Streptomyces avermitilis MA-4680 1217045 NP_827929.1 CDS SAV_6753 NC_003155.4 8071286 8071726 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8071286..8071726 Streptomyces avermitilis MA-4680 1217046 NP_827930.1 CDS SAV_6754 NC_003155.4 8071818 8072402 D PF00300: Phosphoglycerate mutase family; hypothetical protein 8071818..8072402 Streptomyces avermitilis MA-4680 1217047 NP_827931.1 CDS SAV_6755 NC_003155.4 8072399 8072869 R hypothetical protein complement(8072399..8072869) Streptomyces avermitilis MA-4680 1217048 NP_827932.1 CDS SAV_6756 NC_003155.4 8073187 8075319 D arabinosidase 8073187..8075319 Streptomyces avermitilis MA-4680 1217049 NP_827933.1 CDS SAV_6757 NC_003155.4 8075306 8075743 R carboxymuconolactone decarboxylase complement(8075306..8075743) Streptomyces avermitilis MA-4680 1217050 NP_827934.1 CDS SAV_6758 NC_003155.4 8075740 8076159 R MerR family transcriptional regulator complement(8075740..8076159) Streptomyces avermitilis MA-4680 1217051 NP_827935.1 CDS SAV_6759 NC_003155.4 8076350 8076988 R hypothetical protein complement(8076350..8076988) Streptomyces avermitilis MA-4680 1217052 NP_827936.1 CDS SAV_6760 NC_003155.4 8077051 8078250 R hypothetical protein complement(8077051..8078250) Streptomyces avermitilis MA-4680 1217053 NP_827937.1 CDS SAV_6761 NC_003155.4 8078247 8078690 R hypothetical protein complement(8078247..8078690) Streptomyces avermitilis MA-4680 1217054 NP_827938.1 CDS SAV_6762 NC_003155.4 8078754 8079557 R hydroxylase complement(8078754..8079557) Streptomyces avermitilis MA-4680 1217055 NP_827939.1 CDS argC NC_003155.4 8079875 8080903 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 8079875..8080903 Streptomyces avermitilis MA-4680 1211554 NP_827940.1 CDS argJ NC_003155.4 8080900 8082051 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 8080900..8082051 Streptomyces avermitilis MA-4680 1211555 NP_827941.1 CDS argB NC_003155.4 8082048 8082962 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 8082048..8082962 Streptomyces avermitilis MA-4680 1211556 NP_827942.1 CDS argD NC_003155.4 8082959 8084170 D catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 8082959..8084170 Streptomyces avermitilis MA-4680 1211557 NP_827943.1 CDS argR NC_003155.4 8084178 8084714 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 8084178..8084714 Streptomyces avermitilis MA-4680 1211558 NP_827944.1 CDS apbE2 NC_003155.4 8084841 8085578 R thiamine biosynthesis lipoprotein precursor complement(8084841..8085578) Streptomyces avermitilis MA-4680 1211559 NP_827945.1 CDS SAV_6769 NC_003155.4 8085634 8086422 R PF04205: FMN-binding domain; hypothetical protein complement(8085634..8086422) Streptomyces avermitilis MA-4680 1217056 NP_827946.1 CDS SAV_6770 NC_003155.4 8086442 8087821 R PF00175: Oxidoreductase NAD-binding domain; oxidoreductase complement(8086442..8087821) Streptomyces avermitilis MA-4680 1217057 NP_827947.1 CDS SAV_6771 NC_003155.4 8087905 8088402 R PF04205: FMN-binding domain; hypothetical protein complement(8087905..8088402) Streptomyces avermitilis MA-4680 1217058 NP_827948.1 CDS SAV_6772 NC_003155.4 8088410 8089771 R PF00175: Oxidoreductase NAD-binding domain; oxidoreductase complement(8088410..8089771) Streptomyces avermitilis MA-4680 1217059 NP_827949.1 CDS SAV_6773 NC_003155.4 8089920 8090708 D two-component system response regulator 8089920..8090708 Streptomyces avermitilis MA-4680 1217060 NP_827950.1 CDS SAV_6774 NC_003155.4 8090705 8092219 D two-component system sensor kinase 8090705..8092219 Streptomyces avermitilis MA-4680 1217061 NP_827951.1 CDS SAV_6775 NC_003155.4 8092272 8092973 R protein complement(8092272..8092973) Streptomyces avermitilis MA-4680 1217062 NP_827952.1 CDS SAV_6776 NC_003155.4 8092977 8093564 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(8092977..8093564) Streptomyces avermitilis MA-4680 1217063 NP_827953.1 CDS SAV_6777 NC_003155.4 8093803 8094708 R hypothetical protein complement(8093803..8094708) Streptomyces avermitilis MA-4680 1217064 NP_827954.1 CDS argG2 NC_003155.4 8094879 8096093 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 8094879..8096093 Streptomyces avermitilis MA-4680 1211560 NP_827955.1 CDS argH NC_003155.4 8096194 8097627 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 8096194..8097627 Streptomyces avermitilis MA-4680 1211561 NP_827956.1 CDS SAV_6780 NC_003155.4 8097662 8098675 D PF00248: Aldo/keto reductase family; oxidoreductase 8097662..8098675 Streptomyces avermitilis MA-4680 1217065 NP_827957.1 CDS SAV_6781 NC_003155.4 8098734 8099312 D TetR family transcriptional regulator 8098734..8099312 Streptomyces avermitilis MA-4680 1217066 NP_827958.1 CDS SAV_6782 NC_003155.4 8099309 8100826 D PF07690: Major Facilitator Superfamily; multidrug resistance efflux protein 8099309..8100826 Streptomyces avermitilis MA-4680 1217067 NP_827959.1 CDS plsC4 NC_003155.4 8100895 8101566 R 1-acylglycerol-3-phosphate O-acyltransferase complement(8100895..8101566) Streptomyces avermitilis MA-4680 1211562 NP_827960.1 CDS glpQ3 NC_003155.4 8101953 8103134 D glycerophosphoryl diester phosphodiesterase 8101953..8103134 Streptomyces avermitilis MA-4680 1211563 NP_827961.1 CDS sig54 NC_003155.4 8103254 8103760 D ECF subfamily RNA polymerase sigma factor 8103254..8103760 Streptomyces avermitilis MA-4680 1211564 NP_827962.1 CDS SAV_6786 NC_003155.4 8103785 8104303 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8103785..8104303 Streptomyces avermitilis MA-4680 1217068 NP_827963.1 CDS SAV_6787 NC_003155.4 8104529 8104981 R integral membrane protein complement(8104529..8104981) Streptomyces avermitilis MA-4680 1217069 NP_827964.1 CDS SAV_6788 NC_003155.4 8104962 8105321 R integral membrane protein complement(8104962..8105321) Streptomyces avermitilis MA-4680 1217070 NP_827965.1 CDS SAV_6789 NC_003155.4 8105882 8106982 D ABC transporter ATP-binding protein 8105882..8106982 Streptomyces avermitilis MA-4680 1217071 NP_827966.1 CDS SAV_6790 NC_003155.4 8106979 8107758 D ABC transporter permease 8106979..8107758 Streptomyces avermitilis MA-4680 1217072 NP_827967.1 CDS SAV_6791 NC_003155.4 8107830 8108657 D ABC transporter substrate-binding protein 8107830..8108657 Streptomyces avermitilis MA-4680 1217073 NP_827968.1 CDS SAV_6792 NC_003155.4 8108671 8109510 D ABC transporter substrate-binding protein 8108671..8109510 Streptomyces avermitilis MA-4680 1217074 NP_827969.1 CDS SAV_6793 NC_003155.4 8109643 8110281 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8109643..8110281 Streptomyces avermitilis MA-4680 1217075 NP_827970.1 CDS cobL2 NC_003155.4 8110412 8111623 D cobalamin biosynthesis; precorrin-6Y C5,15-methyltransferase 8110412..8111623 Streptomyces avermitilis MA-4680 1217076 NP_827971.1 CDS cobT2 NC_003155.4 8111969 8115829 D cobalamin biosynthesis; nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase 8111969..8115829 Streptomyces avermitilis MA-4680 1211565 NP_827972.1 CDS cysG NC_003155.4 8115977 8117209 D uroporphyrin-III methyltransferase 8115977..8117209 Streptomyces avermitilis MA-4680 1211566 NP_827973.1 CDS SAV_6797 NC_003155.4 8117274 8118092 D rRNA methylase 8117274..8118092 Streptomyces avermitilis MA-4680 1217077 NP_827974.1 CDS SAV_6798 NC_003155.4 8118108 8118503 D mutT-like protein 8118108..8118503 Streptomyces avermitilis MA-4680 1217078 NP_827975.1 CDS pkn30 NC_003155.4 8118587 8119888 R serine/threonine protein kinase complement(8118587..8119888) Streptomyces avermitilis MA-4680 1211567 NP_827976.1 CDS SAV_6800 NC_003155.4 8120530 8120739 D hypothetical protein 8120530..8120739 Streptomyces avermitilis MA-4680 1217079 NP_827977.1 CDS SAV_6801 NC_003155.4 8120921 8121856 D PF01636: Phosphotransferase enzyme family; hypothetical protein 8120921..8121856 Streptomyces avermitilis MA-4680 1217080 NP_827978.1 CDS SAV_6802 NC_003155.4 8121958 8122224 D hypothetical protein 8121958..8122224 Streptomyces avermitilis MA-4680 1217081 NP_827979.1 CDS pabB NC_003155.4 8122893 8124014 D PF00425: chorismate binding enzyme; anthranilate synthase 8122893..8124014 Streptomyces avermitilis MA-4680 1211573 NP_827980.1 CDS SAV_6804 NC_003155.4 8124011 8124832 D PF01063: Aminotransferase class IV; D-alanine aminotransferase 8124011..8124832 Streptomyces avermitilis MA-4680 1217082 NP_827981.1 CDS SAV_6805 NC_003155.4 8124859 8125713 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8124859..8125713 Streptomyces avermitilis MA-4680 1217083 NP_827982.1 CDS SAV_6806 NC_003155.4 8125820 8126350 R PF01323: DSBA-like thioredoxin domain; hypothetical protein complement(8125820..8126350) Streptomyces avermitilis MA-4680 1217084 NP_827983.1 CDS SAV_6807 NC_003155.4 8126556 8126999 D hypothetical protein 8126556..8126999 Streptomyces avermitilis MA-4680 1217085 NP_827984.1 CDS SAV_6808 NC_003155.4 8127180 8127332 D hypothetical protein 8127180..8127332 Streptomyces avermitilis MA-4680 1217086 NP_827985.1 CDS SAV_6809 NC_003155.4 8127548 8128108 R PF07336: Protein of unknown function (DUF1470); hypothetical protein complement(8127548..8128108) Streptomyces avermitilis MA-4680 1217087 NP_827986.1 CDS ssgA2 NC_003155.4 8128420 8128899 R PF04686: Streptomyces sporulation and cell division protein, SsgA; cell division protein, regulatory protein complement(8128420..8128899) Streptomyces avermitilis MA-4680 1217088 NP_827987.1 CDS SAV_6811 NC_003155.4 8129024 8129458 D hypothetical protein 8129024..8129458 Streptomyces avermitilis MA-4680 1217089 NP_827988.1 CDS SAV_6812 NC_003155.4 8130180 8131466 D ABC transporter substrate-binding protein 8130180..8131466 Streptomyces avermitilis MA-4680 1217090 NP_827989.1 CDS SAV_6813 NC_003155.4 8131463 8132434 D ABC transporter permease 8131463..8132434 Streptomyces avermitilis MA-4680 1217091 NP_827990.1 CDS SAV_6814 NC_003155.4 8132404 8133312 D ABC transporter permease 8132404..8133312 Streptomyces avermitilis MA-4680 1217092 NP_827991.1 CDS SAV_6815 NC_003155.4 8133314 8133961 D hypothetical protein 8133314..8133961 Streptomyces avermitilis MA-4680 1217093 NP_827992.1 CDS SAV_6816 NC_003155.4 8134457 8136928 D hypothetical protein 8134457..8136928 Streptomyces avermitilis MA-4680 1217094 NP_827993.1 CDS SAV_6817 NC_003155.4 8136947 8139337 R PF01970: Integral membrane protein DUF112; integral membrane protein complement(8136947..8139337) Streptomyces avermitilis MA-4680 1217095 NP_827994.1 CDS SAV_6818 NC_003155.4 8139440 8139898 D PF03364: Streptomyces cyclase/dehydrase; hypothetical protein 8139440..8139898 Streptomyces avermitilis MA-4680 1217096 NP_827995.1 CDS dnaQ2 NC_003155.4 8140086 8140811 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(8140086..8140811) Streptomyces avermitilis MA-4680 1211576 NP_827996.1 CDS SAV_6820 NC_003155.4 8140980 8141546 D hypothetical protein 8140980..8141546 Streptomyces avermitilis MA-4680 1217097 NP_827997.1 CDS SAV_6821 NC_003155.4 8141543 8142763 D hypothetical protein 8141543..8142763 Streptomyces avermitilis MA-4680 1217098 NP_827998.1 CDS thrS NC_003155.4 8142864 8144840 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 8142864..8144840 Streptomyces avermitilis MA-4680 1211577 NP_827999.1 CDS SAV_6823 NC_003155.4 8145199 8145762 D HIT family protein 8145199..8145762 Streptomyces avermitilis MA-4680 1217099 NP_828000.1 CDS SAV_6824 NC_003155.4 8145882 8147543 R hypothetical protein complement(8145882..8147543) Streptomyces avermitilis MA-4680 1217100 NP_828001.1 CDS fusA2 NC_003155.4 8147772 8149970 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(8147772..8149970) Streptomyces avermitilis MA-4680 1211578 NP_828002.1 CDS pgsA2 NC_003155.4 8150189 8150923 D PF01066: CDP-alcohol phosphatidyltransferase; phosphatidylglycerophosphate synthase 8150189..8150923 Streptomyces avermitilis MA-4680 1217101 NP_828003.1 CDS plsC5 NC_003155.4 8150920 8151846 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 8150920..8151846 Streptomyces avermitilis MA-4680 1211579 NP_828004.1 CDS SAV_6828 NC_003155.4 8151843 8153003 D glycosyltransferase 8151843..8153003 Streptomyces avermitilis MA-4680 1217102 NP_828005.1 CDS SAV_6829 NC_003155.4 8153398 8153952 D protein 8153398..8153952 Streptomyces avermitilis MA-4680 1217103 NP_828006.1 CDS pdx1 NC_003155.4 8154087 8155001 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 8154087..8155001 Streptomyces avermitilis MA-4680 1211580 NP_828007.1 CDS SAV_6831 NC_003155.4 8155015 8155620 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 8155015..8155620 Streptomyces avermitilis MA-4680 1217104 NP_828008.1 CDS SAV_6832 NC_003155.4 8155698 8156450 D PF01709: Domain of unknown function DUF28; hypothetical protein 8155698..8156450 Streptomyces avermitilis MA-4680 1217105 NP_828009.1 CDS ruvC NC_003155.4 8156649 8157179 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 8156649..8157179 Streptomyces avermitilis MA-4680 1211581 NP_828010.1 CDS ruvA NC_003155.4 8157176 8157787 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 8157176..8157787 Streptomyces avermitilis MA-4680 1211582 NP_828011.1 CDS ruvB NC_003155.4 8157959 8159029 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 8157959..8159029 Streptomyces avermitilis MA-4680 1211583 NP_828012.1 CDS SAV_6836 NC_003155.4 8159193 8159696 D PF02699: Preprotein translocase subunit; protein 8159193..8159696 Streptomyces avermitilis MA-4680 1217106 NP_828013.1 CDS secD NC_003155.4 8159839 8161593 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 8159839..8161593 Streptomyces avermitilis MA-4680 1211584 NP_828014.1 CDS secF NC_003155.4 8161595 8162701 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 8161595..8162701 Streptomyces avermitilis MA-4680 1211585 NP_828015.1 CDS apt NC_003155.4 8162698 8163246 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 8162698..8163246 Streptomyces avermitilis MA-4680 1211586 NP_828016.1 CDS relA2 NC_003155.4 8164005 8166542 D PF04607: Region found in RelA / SpoT proteins; ppGpp synthetase 8164005..8166542 Streptomyces avermitilis MA-4680 1211587 NP_828017.1 CDS SAV_6841 NC_003155.4 8166677 8167906 R PF03993: Domain of Unknown Function (DUF349); hypothetical protein complement(8166677..8167906) Streptomyces avermitilis MA-4680 1217107 NP_828018.1 CDS ppiB NC_003155.4 8168042 8168875 R peptidyl-prolyl cis-trans isomerase complement(8168042..8168875) Streptomyces avermitilis MA-4680 1211588 NP_828019.1 CDS SAV_6843 NC_003155.4 8169042 8169749 D PF00753: Metallo-beta-lactamase superfamily; hydrolase 8169042..8169749 Streptomyces avermitilis MA-4680 1217108 NP_828020.1 CDS hisS NC_003155.4 8169763 8171025 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 8169763..8171025 Streptomyces avermitilis MA-4680 1211589 NP_828021.1 CDS SAV_6845 NC_003155.4 8171593 8172231 D integral membrane protein 8171593..8172231 Streptomyces avermitilis MA-4680 1217109 NP_828022.1 CDS SAV_6846 NC_003155.4 8172295 8173656 D recombination factor protein RarA 8172295..8173656 Streptomyces avermitilis MA-4680 1217110 NP_828023.1 CDS rpsD NC_003155.4 8173971 8174585 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 8173971..8174585 Streptomyces avermitilis MA-4680 1211590 NP_828024.1 CDS SAV_6848 NC_003155.4 8174761 8175216 D PF05962: Bacterial protein of unknown function (DUF886); protein 8174761..8175216 Streptomyces avermitilis MA-4680 1217111 NP_828025.1 CDS SAV_6849 NC_003155.4 8175224 8175574 D protein 8175224..8175574 Streptomyces avermitilis MA-4680 1217112 NP_828026.1 CDS alaS NC_003155.4 8175574 8178246 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 8175574..8178246 Streptomyces avermitilis MA-4680 1211591 NP_828027.1 CDS SAV_6851 NC_003155.4 8178256 8178726 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 8178256..8178726 Streptomyces avermitilis MA-4680 1217113 NP_828028.1 CDS SAV_6852 NC_003155.4 8178852 8180669 D PF02618: Aminodeoxychorismate lyase, a pyridoxal 5'-phosphate-dependent enzyme that converts 4-aminodeoxychorismate to pyruvate and p-aminobenzoate; aminodeoxychorismate lyase 8178852..8180669 Streptomyces avermitilis MA-4680 1217114 NP_828029.1 CDS aroE NC_003155.4 8180666 8181502 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 8180666..8181502 Streptomyces avermitilis MA-4680 1211592 NP_828030.1 CDS aroC NC_003155.4 8181892 8183076 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 8181892..8183076 Streptomyces avermitilis MA-4680 1211593 NP_828031.1 CDS aroK NC_003155.4 8183073 8183588 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 8183073..8183588 Streptomyces avermitilis MA-4680 1211594 NP_828032.1 CDS aroB NC_003155.4 8183585 8184676 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 8183585..8184676 Streptomyces avermitilis MA-4680 1211595 NP_828033.1 CDS SAV_6857 NC_003155.4 8184843 8185733 D hypothetical protein 8184843..8185733 Streptomyces avermitilis MA-4680 1217115 NP_828034.1 CDS SAV_6858 NC_003155.4 8185869 8186975 D PF00557: metallopeptidase family M24; peptidase 8185869..8186975 Streptomyces avermitilis MA-4680 1217116 NP_828035.1 CDS efp NC_003155.4 8187035 8187601 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 8187035..8187601 Streptomyces avermitilis MA-4680 1211596 NP_828036.1 CDS nusB NC_003155.4 8187604 8188038 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 8187604..8188038 Streptomyces avermitilis MA-4680 1211597 NP_828037.1 CDS SAV_6861 NC_003155.4 8188808 8189332 R DNA-binding protein complement(8188808..8189332) Streptomyces avermitilis MA-4680 1217117 NP_828038.1 CDS pyrR NC_003155.4 8189574 8190152 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 8189574..8190152 Streptomyces avermitilis MA-4680 1211598 NP_828039.1 CDS pyrB NC_003155.4 8190239 8191216 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 8190239..8191216 Streptomyces avermitilis MA-4680 1211599 NP_828040.1 CDS pyrC NC_003155.4 8191222 8192508 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 8191222..8192508 Streptomyces avermitilis MA-4680 1211600 NP_828041.1 CDS SAV_6865 NC_003155.4 8192505 8193125 D integral membrane protein 8192505..8193125 Streptomyces avermitilis MA-4680 1217118 NP_828042.1 CDS carA NC_003155.4 8193122 8194264 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 8193122..8194264 Streptomyces avermitilis MA-4680 1211601 NP_828043.1 CDS carB NC_003155.4 8194257 8197565 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 8194257..8197565 Streptomyces avermitilis MA-4680 1211602 NP_828044.1 CDS pyrD NC_003155.4 8197641 8198747 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 8197641..8198747 Streptomyces avermitilis MA-4680 1211603 NP_828045.1 CDS pyrF NC_003155.4 8198744 8199586 D type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 8198744..8199586 Streptomyces avermitilis MA-4680 1211604 NP_828046.1 CDS SAV_6870 NC_003155.4 8199842 8200165 D hypothetical protein 8199842..8200165 Streptomyces avermitilis MA-4680 1217119 NP_828047.1 CDS gmk NC_003155.4 8200203 8200796 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 8200203..8200796 Streptomyces avermitilis MA-4680 1211605 NP_828048.1 CDS rpoZ NC_003155.4 8200837 8201109 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 8200837..8201109 Streptomyces avermitilis MA-4680 1211606 NP_828049.1 CDS dfp NC_003155.4 8201233 8202450 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 8201233..8202450 Streptomyces avermitilis MA-4680 1211607 NP_828050.1 CDS metK NC_003155.4 8202691 8203899 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 8202691..8203899 Streptomyces avermitilis MA-4680 1211608 NP_828051.1 CDS priA NC_003155.4 8204328 8206490 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 8204328..8206490 Streptomyces avermitilis MA-4680 1211609 NP_828052.1 CDS SAV_6876 NC_003155.4 8206683 8207225 R hypothetical protein complement(8206683..8207225) Streptomyces avermitilis MA-4680 1217120 NP_828053.1 CDS fmt NC_003155.4 8207585 8208517 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 8207585..8208517 Streptomyces avermitilis MA-4680 1211610 NP_828054.1 CDS SAV_6878 NC_003155.4 8209360 8210790 D PF01189: NOL1/NOP2/sun family; RNA-binding Sun protein 8209360..8210790 Streptomyces avermitilis MA-4680 1217121 NP_828055.1 CDS SAV_6879 NC_003155.4 8210771 8212927 R similar to actII-3, PF03176: MMPL family; hypothetical protein complement(8210771..8212927) Streptomyces avermitilis MA-4680 1217122 NP_828056.1 CDS rpe NC_003155.4 8213111 8213797 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 8213111..8213797 Streptomyces avermitilis MA-4680 1211611 NP_828057.1 CDS SAV_6881 NC_003155.4 8213876 8214919 D transcriptional regulator 8213876..8214919 Streptomyces avermitilis MA-4680 1217123 NP_828058.1 CDS SAV_6882 NC_003155.4 8214961 8215368 D PF00545: ribonuclease; guanyl-specific ribonuclease Sa3 precursor (RNase Sa3) 8214961..8215368 Streptomyces avermitilis MA-4680 1217124 NP_828059.1 CDS SAV_6883 NC_003155.4 8215365 8215742 D hypothetical protein 8215365..8215742 Streptomyces avermitilis MA-4680 1217125 NP_828060.1 CDS guaB3 NC_003155.4 8215841 8217292 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 8215841..8217292 Streptomyces avermitilis MA-4680 1211612 NP_828061.1 CDS SAV_6885 NC_003155.4 8217379 8217879 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8217379..8217879 Streptomyces avermitilis MA-4680 1217126 NP_828062.1 CDS SAV_6886 NC_003155.4 8218131 8219609 D amino acid permease 8218131..8219609 Streptomyces avermitilis MA-4680 1217127 NP_828063.1 CDS SAV_6887 NC_003155.4 8219620 8220072 D transcription regulator AsnC 8219620..8220072 Streptomyces avermitilis MA-4680 1217128 NP_828064.1 CDS SAV_6888 NC_003155.4 8220069 8220266 R hypothetical protein complement(8220069..8220266) Streptomyces avermitilis MA-4680 1217129 NP_828065.1 CDS SAV_6889 NC_003155.4 8220462 8222939 D sensor-like histidine kinase 8220462..8222939 Streptomyces avermitilis MA-4680 1217130 NP_828066.1 CDS SAV_6890 NC_003155.4 8222929 8223468 D PF03259: Roadblock/LC7 domain; hypothetical protein 8222929..8223468 Streptomyces avermitilis MA-4680 1217131 NP_828067.1 CDS SAV_6891 NC_003155.4 8223476 8223853 D PF05331: Protein of unknown function (DUF742); hypothetical protein 8223476..8223853 Streptomyces avermitilis MA-4680 1217132 NP_828068.1 CDS SAV_6892 NC_003155.4 8224288 8225076 D PF00795: Carbon-nitrogen hydrolase; hydrolase 8224288..8225076 Streptomyces avermitilis MA-4680 1217133 NP_828069.1 CDS SAV_6893 NC_003155.4 8225124 8226821 D amino oxidase 8225124..8226821 Streptomyces avermitilis MA-4680 1217134 NP_828070.1 CDS SAV_6894 NC_003155.4 8226837 8227766 R PF00296: Luciferase-like monooxygenase; hypothetical protein complement(8226837..8227766) Streptomyces avermitilis MA-4680 1217135 NP_828071.1 CDS SAV_6895 NC_003155.4 8227870 8228544 R hypothetical protein complement(8227870..8228544) Streptomyces avermitilis MA-4680 1217136 NP_828072.1 CDS celA5 NC_003155.4 8228717 8229829 D endo-1,4-beta-glucanase 8228717..8229829 Streptomyces avermitilis MA-4680 1211613 NP_828073.1 CDS pyrP NC_003155.4 8229811 8231250 R uracyl permease complement(8229811..8231250) Streptomyces avermitilis MA-4680 1211614 NP_828074.1 CDS SAV_6898 NC_003155.4 8231372 8232637 D hypothetical protein 8231372..8232637 Streptomyces avermitilis MA-4680 1217137 NP_828075.1 CDS SAV_6899 NC_003155.4 8232735 8233205 D PF03061: Thioesterase superfamily; hypothetical protein 8232735..8233205 Streptomyces avermitilis MA-4680 1217138 NP_828076.1 CDS SAV_6900 NC_003155.4 8233165 8234376 R PF07690: Major Facilitator Superfamily; integral membrane transport protein complement(8233165..8234376) Streptomyces avermitilis MA-4680 1217139 NP_828077.1 CDS SAV_6901 NC_003155.4 8234502 8235689 D transcriptional regulator 8234502..8235689 Streptomyces avermitilis MA-4680 1217140 NP_828078.1 CDS ribC NC_003155.4 8236486 8237094 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 8236486..8237094 Streptomyces avermitilis MA-4680 1211615 NP_828079.1 CDS SAV_6903 NC_003155.4 8237091 8237735 D PF04973: Nicotinamide mononucleotide transporter; integral membrane protein 8237091..8237735 Streptomyces avermitilis MA-4680 1217141 NP_828080.1 CDS ribA1 NC_003155.4 8237732 8239021 D bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 8237732..8239021 Streptomyces avermitilis MA-4680 1211616 NP_828081.1 CDS ribH NC_003155.4 8239041 8239526 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 8239041..8239526 Streptomyces avermitilis MA-4680 1211617 NP_828082.1 CDS hisE NC_003155.4 8239561 8239833 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 8239561..8239833 Streptomyces avermitilis MA-4680 1211618 NP_828083.1 CDS hisG NC_003155.4 8239883 8240740 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 8239883..8240740 Streptomyces avermitilis MA-4680 1211619 NP_828084.1 CDS SAV_6908 NC_003155.4 8240755 8241219 D hypothetical protein 8240755..8241219 Streptomyces avermitilis MA-4680 1217142 NP_828085.1 CDS SAV_6909 NC_003155.4 8241446 8242867 D PF01595: Domain of unknown function DUF21, PF03471: Transporter associated domain, PF00571: CBS domain; integral membrane protein 8241446..8242867 Streptomyces avermitilis MA-4680 1217143 NP_828086.1 CDS SAV_6910 NC_003155.4 8242864 8243958 D PF01595: Domain of unknown function DUF21; integral membrane protein 8242864..8243958 Streptomyces avermitilis MA-4680 1217144 NP_828087.1 CDS SAV_6911 NC_003155.4 8244005 8245867 R PF00004: ATPase family associated with various cellular activities (AAA); ATPase complement(8244005..8245867) Streptomyces avermitilis MA-4680 1217145 NP_828088.1 CDS SAV_6912 NC_003155.4 8246299 8246952 R PF00485: Phosphoribulokinase / Uridine kinase family; hypothetical protein complement(8246299..8246952) Streptomyces avermitilis MA-4680 1217146 NP_828089.1 CDS SAV_6913 NC_003155.4 8247166 8248164 D hypothetical protein 8247166..8248164 Streptomyces avermitilis MA-4680 1217147 NP_828090.1 CDS SAV_6914 NC_003155.4 8248213 8249763 D amino acid permease 8248213..8249763 Streptomyces avermitilis MA-4680 1217148 NP_828091.1 CDS SAV_6915 NC_003155.4 8249962 8251314 D hypothetical protein 8249962..8251314 Streptomyces avermitilis MA-4680 1217149 NP_828092.1 CDS SAV_6916 NC_003155.4 8251453 8251593 D hypothetical protein 8251453..8251593 Streptomyces avermitilis MA-4680 1217150 NP_828093.1 CDS SAV_6917 NC_003155.4 8251721 8252380 D TetR family transcriptional regulator 8251721..8252380 Streptomyces avermitilis MA-4680 1217151 NP_828094.1 CDS chiD NC_003155.4 8252433 8253716 R chitinase complement(8252433..8253716) Streptomyces avermitilis MA-4680 1211620 NP_828095.1 CDS fadE2 NC_003155.4 8254072 8255244 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 8254072..8255244 Streptomyces avermitilis MA-4680 1211621 NP_828096.1 CDS SAV_6920 NC_003155.4 8256320 8256748 R hypothetical protein complement(8256320..8256748) Streptomyces avermitilis MA-4680 1217152 NP_828097.1 CDS SAV_6921 NC_003155.4 8256960 8257457 D transcription regulator AsnC 8256960..8257457 Streptomyces avermitilis MA-4680 1217153 NP_828098.1 CDS SAV_6922 NC_003155.4 8257505 8259127 D hypothetical protein 8257505..8259127 Streptomyces avermitilis MA-4680 1217154 NP_828099.1 CDS SAV_6923 NC_003155.4 8259737 8260534 D PF00535: Glycosyl transferase; glycosyl transferase 8259737..8260534 Streptomyces avermitilis MA-4680 1217155 NP_828100.1 CDS SAV_6924 NC_003155.4 8260622 8261194 D PF04186: FxsA cytoplasmic membrane protein; hypothetical protein 8260622..8261194 Streptomyces avermitilis MA-4680 1217156 NP_828101.1 CDS SAV_6925 NC_003155.4 8261372 8261746 R hypothetical protein complement(8261372..8261746) Streptomyces avermitilis MA-4680 1217157 NP_828102.1 CDS SAV_6926 NC_003155.4 8262014 8263360 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(8262014..8263360) Streptomyces avermitilis MA-4680 1217158 NP_828103.1 CDS glpQ4 NC_003155.4 8263401 8264168 R glycerophosphoryl diester phosphodiesterase complement(8263401..8264168) Streptomyces avermitilis MA-4680 1211622 NP_828104.1 CDS SAV_6929 NC_003155.4 8264165 8264932 R PF02588: Uncharacterized BCR, YitT family COG1284; hypothetical protein complement(8264165..8264932) Streptomyces avermitilis MA-4680 1217159 NP_828105.1 CDS SAV_6928 NC_003155.4 8264931 8266430 D similar to PdxR involved in regulation of pyridoxal phosphate; GntR family transcriptional regulator 8264931..8266430 Streptomyces avermitilis MA-4680 1217160 NP_828106.1 CDS SAV_6930 NC_003155.4 8266448 8268115 R PF01580: FtsK/SpoIIIE family; hypothetical protein complement(8266448..8268115) Streptomyces avermitilis MA-4680 1217161 NP_828107.1 CDS SAV_6931 NC_003155.4 8268153 8268347 R hypothetical protein complement(8268153..8268347) Streptomyces avermitilis MA-4680 1217162 NP_828108.1 CDS SAV_6932 NC_003155.4 8268640 8269044 D PF00023: Ankyrin repeat; ankyrin-like protein 8268640..8269044 Streptomyces avermitilis MA-4680 1217163 NP_828109.1 CDS SAV_6933 NC_003155.4 8269346 8270764 D hypothetical protein 8269346..8270764 Streptomyces avermitilis MA-4680 1217164 NP_828110.1 CDS SAV_6934 NC_003155.4 8270944 8272107 D PF00534: Glycosyl transferases group 1; glycosyl transferase 8270944..8272107 Streptomyces avermitilis MA-4680 1217165 NP_828111.1 CDS SAV_6935 NC_003155.4 8272104 8273312 D PF00534: Glycosyl transferases group 1; glycosyl transferase 8272104..8273312 Streptomyces avermitilis MA-4680 1217166 NP_828112.1 CDS SAV_6936 NC_003155.4 8273309 8274163 D PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein 8273309..8274163 Streptomyces avermitilis MA-4680 1217167 NP_828113.1 CDS kipA NC_003155.4 8274168 8275037 R antagonist of KipI complement(8274168..8275037) Streptomyces avermitilis MA-4680 1211623 NP_828114.1 CDS kipI NC_003155.4 8275034 8275651 R inhibitor of KinA complement(8275034..8275651) Streptomyces avermitilis MA-4680 1211624 NP_828115.1 CDS SAV_6939 NC_003155.4 8275648 8276400 R LamB/YcsF family protein complement(8275648..8276400) Streptomyces avermitilis MA-4680 1217168 NP_828116.1 CDS SAV_6940 NC_003155.4 8276413 8277237 R PF07286: Protein of unknown function (DUF1445); hypothetical protein complement(8276413..8277237) Streptomyces avermitilis MA-4680 1217169 NP_828117.1 CDS SAV_6941 NC_003155.4 8277234 8278553 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(8277234..8278553) Streptomyces avermitilis MA-4680 1217170 NP_828118.1 CDS SAV_6942 NC_003155.4 8278809 8279510 D GntR family transcriptional regulator 8278809..8279510 Streptomyces avermitilis MA-4680 1217171 NP_828119.1 CDS SAV_6943 NC_003155.4 8279643 8281160 D hypothetical protein 8279643..8281160 Streptomyces avermitilis MA-4680 1217172 NP_828120.1 CDS SAV_6944 NC_003155.4 8281255 8282133 D hypothetical protein 8281255..8282133 Streptomyces avermitilis MA-4680 1217173 NP_828121.1 CDS SAV_6945 NC_003155.4 8282203 8286903 D PF01576: Myosin tail; hypothetical protein 8282203..8286903 Streptomyces avermitilis MA-4680 1217174 NP_828122.1 CDS SAV_6946 NC_003155.4 8286990 8288540 R PF00732: GMC oxidoreductase; choline oxidase complement(8286990..8288540) Streptomyces avermitilis MA-4680 1217175 NP_828123.1 CDS SAV_6947 NC_003155.4 8288644 8290212 R amino acid permease complement(8288644..8290212) Streptomyces avermitilis MA-4680 1217176 NP_828124.1 CDS gbsA3 NC_003155.4 8290309 8291832 R glycine betaine aldehyde dehydrogenase complement(8290309..8291832) Streptomyces avermitilis MA-4680 1211625 NP_828125.1 CDS SAV_6949 NC_003155.4 8291796 8292944 R PF00355: Rieske [2Fe-2S] domain; ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase complement(8291796..8292944) Streptomyces avermitilis MA-4680 1217177 NP_828126.1 CDS solA NC_003155.4 8292956 8294110 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(8292956..8294110) Streptomyces avermitilis MA-4680 1211626 NP_828127.1 CDS SAV_6951 NC_003155.4 8294120 8296576 R PF01571: Glycine cleavage T-protein (aminomethyl transferase); sarcosine dehydrogenase complement(8294120..8296576) Streptomyces avermitilis MA-4680 1217178 NP_828128.1 CDS blaB4 NC_003155.4 8296623 8297249 R PF00753: Metallo-beta-lactamase superfamily; metallo-beta-lactamase complement(8296623..8297249) Streptomyces avermitilis MA-4680 1211627 NP_828129.1 CDS adhA10 NC_003155.4 8297246 8298337 R PF00107: Zinc-binding dehydrogenase; alcohol dehydrogenase complement(8297246..8298337) Streptomyces avermitilis MA-4680 1217179 NP_828130.1 CDS SAV_6954 NC_003155.4 8298618 8299448 R IclR family transcriptional regulator complement(8298618..8299448) Streptomyces avermitilis MA-4680 1217180 NP_828131.1 CDS hcaC2 NC_003155.4 8299712 8300032 D 3-phenylpropionate dioxygenase ferredoxin subunit 8299712..8300032 Streptomyces avermitilis MA-4680 1217181 NP_828132.1 CDS fprF NC_003155.4 8300184 8301425 D ferredoxin reductase 8300184..8301425 Streptomyces avermitilis MA-4680 1211628 NP_828133.1 CDS SAV_6957 NC_003155.4 8301571 8302188 R hypothetical protein complement(8301571..8302188) Streptomyces avermitilis MA-4680 1217182 NP_828134.1 CDS cvnA11 NC_003155.4 8302609 8305449 D multi-component regulatory system-11; sensor-like histidine kinase 8302609..8305449 Streptomyces avermitilis MA-4680 1211629 NP_828135.1 CDS cvnB11 NC_003155.4 8305446 8305886 D multi-component regulatory system-11, PF03259: Roadblock/LC7 domain; hypothetical protein 8305446..8305886 Streptomyces avermitilis MA-4680 1211630 NP_828136.1 CDS cvnC11 NC_003155.4 8305896 8306291 D multi-component regulatory system-11, PF05331: Protein of unknown function (DUF742); hypothetical protein 8305896..8306291 Streptomyces avermitilis MA-4680 1211631 NP_828137.1 CDS SAV_6961 NC_003155.4 8306316 8309930 D PF02538: Hydantoinase B/oxoprolinase; hydantoinase/oxoprolinase 8306316..8309930 Streptomyces avermitilis MA-4680 1217183 NP_828138.1 CDS cvnD11 NC_003155.4 8309911 8310516 D multi-component regulatory system-11; ATP/GTP-binding protein 8309911..8310516 Streptomyces avermitilis MA-4680 1211632 NP_828139.1 CDS glpK2 NC_003155.4 8310646 8312169 R glycerol kinase complement(8310646..8312169) Streptomyces avermitilis MA-4680 1211633 NP_828140.1 CDS glpF2 NC_003155.4 8312188 8312937 R glycerol uptake facilitator protein complement(8312188..8312937) Streptomyces avermitilis MA-4680 1217184 NP_828141.1 CDS SAV_6965 NC_003155.4 8313344 8314969 R PF00563: EAL domain; hypothetical protein complement(8313344..8314969) Streptomyces avermitilis MA-4680 1217185 NP_828142.1 CDS SAV_6966 NC_003155.4 8315096 8316286 R PF00108: Thiolase, N-terminal domain; lipid-transfer protein complement(8315096..8316286) Streptomyces avermitilis MA-4680 1217186 NP_828143.1 CDS SAV_6967 NC_003155.4 8316283 8316729 R PF01796: Domain of unknown function DUF35; hypothetical protein complement(8316283..8316729) Streptomyces avermitilis MA-4680 1217187 NP_828144.1 CDS SAV_6968 NC_003155.4 8316959 8317495 D Nudix/MutT family protein 8316959..8317495 Streptomyces avermitilis MA-4680 1217188 NP_828145.1 CDS SAV_6969 NC_003155.4 8317535 8319901 R PF01055: Glycosyl hydrolases family 31; glycosyl hydrolase complement(8317535..8319901) Streptomyces avermitilis MA-4680 1217189 NP_828146.1 CDS acsA2 NC_003155.4 8320115 8322082 D AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 8320115..8322082 Streptomyces avermitilis MA-4680 1211634 NP_828147.1 CDS SAV_6971 NC_003155.4 8322083 8323402 R GntR family transcriptional regulator complement(8322083..8323402) Streptomyces avermitilis MA-4680 1217190 NP_828148.1 CDS SAV_6972 NC_003155.4 8323448 8324722 D PF07690: Major Facilitator Superfamily; membrane transport protein 8323448..8324722 Streptomyces avermitilis MA-4680 1217191 NP_828149.1 CDS SAV_6973 NC_003155.4 8324745 8325638 D hypothetical protein 8324745..8325638 Streptomyces avermitilis MA-4680 1217192 NP_828150.1 CDS ptsP NC_003155.4 8325726 8327396 R PF02896: PEP-utilising enzyme, TIM barrel domain; phosphoenolpyruvate-protein phosphotransferase complement(8325726..8327396) Streptomyces avermitilis MA-4680 1211635 NP_828151.1 CDS ptsA NC_003155.4 8327473 8327922 R PF00358: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphoenolpyruvate-dependent sugar phosphotransferase complement(8327473..8327922) Streptomyces avermitilis MA-4680 1211636 NP_828152.1 CDS pgsA3 NC_003155.4 8333915 8334523 D CDP-diacylglycerol--glycerol-3- phosphate 3-phosphatidyl-transferase 8333915..8334523 Streptomyces avermitilis MA-4680 1211640 NP_828153.1 CDS mpg3 NC_003155.4 8334639 8337134 D mannose-1-phosphate guanyltransferase 8334639..8337134 Streptomyces avermitilis MA-4680 1211641 NP_828154.1 CDS SAV_6978 NC_003155.4 8337225 8338130 D PF05949: Bacterial protein of unknown function (DUF881); hypothetical protein 8337225..8338130 Streptomyces avermitilis MA-4680 1217193 NP_828155.1 CDS SAV_6979 NC_003155.4 8338127 8338459 D PF06947: Protein of unknown function (DUF1290); hypothetical protein 8338127..8338459 Streptomyces avermitilis MA-4680 1217194 NP_828156.1 CDS SAV_6980 NC_003155.4 8338456 8339331 D PF05949: Bacterial protein of unknown function (DUF881); hypothetical protein 8338456..8339331 Streptomyces avermitilis MA-4680 1217195 NP_828157.1 CDS SAV_6981 NC_003155.4 8339393 8340367 D PF00498: FHA domain; hypothetical protein 8339393..8340367 Streptomyces avermitilis MA-4680 1217196 NP_828158.1 CDS SAV_6982 NC_003155.4 8340386 8341141 D PF00376: MerR family regulatory protein; hypothetical protein 8340386..8341141 Streptomyces avermitilis MA-4680 1217197 NP_828159.1 CDS SAV_6983 NC_003155.4 8341228 8341701 D PF02577: Uncharacterised ACR, COG1259; hypothetical protein 8341228..8341701 Streptomyces avermitilis MA-4680 1217198 NP_828160.1 CDS SAV_6984 NC_003155.4 8341986 8342621 D hypothetical protein 8341986..8342621 Streptomyces avermitilis MA-4680 1217199 NP_828161.1 CDS dinB NC_003155.4 8342842 8344551 D Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits; DNA polymerase IV 8342842..8344551 Streptomyces avermitilis MA-4680 1211642 NP_828162.1 CDS SAV_6986 NC_003155.4 8344473 8344895 R PF05239: PRC-barrel domain; hypothetical protein complement(8344473..8344895) Streptomyces avermitilis MA-4680 1217200 NP_828163.1 CDS gcvB NC_003155.4 8345154 8348117 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 8345154..8348117 Streptomyces avermitilis MA-4680 1211643 NP_828164.1 CDS SAV_6988 NC_003155.4 8348288 8348494 R hypothetical protein complement(8348288..8348494) Streptomyces avermitilis MA-4680 1217201 NP_828165.1 CDS SAV_6989 NC_003155.4 8348882 8349466 R hypothetical protein complement(8348882..8349466) Streptomyces avermitilis MA-4680 1217202 NP_828166.1 CDS SAV_6990 NC_003155.4 8349837 8351522 D PF04107: Glutamate-cysteine ligase family 2(GCS2); hypothetical protein 8349837..8351522 Streptomyces avermitilis MA-4680 1217203 NP_828167.1 CDS SAV_6991 NC_003155.4 8351630 8353501 R PF00092: von Willebrand factor type A domain; hypothetical protein complement(8351630..8353501) Streptomyces avermitilis MA-4680 1217204 NP_828168.1 CDS SAV_6992 NC_003155.4 8353578 8354378 D PF02517: CAAX amino terminal protease family; hypothetical protein 8353578..8354378 Streptomyces avermitilis MA-4680 1217205 NP_828169.1 CDS phzC NC_003155.4 8354368 8355186 R PF02567: Phenazine biosynthesis-like protein; phenazine biosynthesis protein complement(8354368..8355186) Streptomyces avermitilis MA-4680 1217206 NP_828170.1 CDS SAV_6994 NC_003155.4 8355594 8356247 D PadR-like family transcriptional regulator 8355594..8356247 Streptomyces avermitilis MA-4680 1217207 NP_828171.1 CDS SAV_6995 NC_003155.4 8356323 8356829 R PF03364: Streptomyces cyclase/dehydrase; hypothetical protein complement(8356323..8356829) Streptomyces avermitilis MA-4680 1217208 NP_828172.1 CDS SAV_6996 NC_003155.4 8356906 8357658 D PF02861: Clp amino terminal domain; hypothetical protein 8356906..8357658 Streptomyces avermitilis MA-4680 1217209 NP_828173.1 CDS SAV_6997 NC_003155.4 8357775 8358782 D PF00892: Integral membrane protein DUF6; hypothetical protein 8357775..8358782 Streptomyces avermitilis MA-4680 1217210 NP_828174.1 CDS SAV_6998 NC_003155.4 8359004 8359996 D PF00892: Integral membrane protein DUF6; hypothetical protein 8359004..8359996 Streptomyces avermitilis MA-4680 1217211 NP_828175.1 CDS SAV_6999 NC_003155.4 8360388 8361089 R hypothetical protein complement(8360388..8361089) Streptomyces avermitilis MA-4680 1217212 NP_828176.1 CDS SAV_7000 NC_003155.4 8361113 8362444 D GntR family transcriptional regulator 8361113..8362444 Streptomyces avermitilis MA-4680 1217213 NP_828177.1 CDS SAV_7001 NC_003155.4 8362446 8363381 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(8362446..8363381) Streptomyces avermitilis MA-4680 1217214 NP_828178.1 CDS SAV_7002 NC_003155.4 8363460 8364359 D LysR family transcriptional regulator 8363460..8364359 Streptomyces avermitilis MA-4680 1217215 NP_828179.1 CDS SAV_7003 NC_003155.4 8364506 8364973 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(8364506..8364973) Streptomyces avermitilis MA-4680 1217216 NP_828180.1 CDS SAV_7004 NC_003155.4 8365030 8365752 D PF00857: Isochorismatase family; hypothetical protein 8365030..8365752 Streptomyces avermitilis MA-4680 1217217 NP_828181.1 CDS SAV_7005 NC_003155.4 8365833 8366324 R iron sulphur protein complement(8365833..8366324) Streptomyces avermitilis MA-4680 1217218 NP_828182.1 CDS SAV_7006 NC_003155.4 8366488 8367243 D hypothetical protein 8366488..8367243 Streptomyces avermitilis MA-4680 1217219 NP_828183.1 CDS SAV_7007 NC_003155.4 8367240 8367623 D hypothetical protein 8367240..8367623 Streptomyces avermitilis MA-4680 1217220 NP_828184.1 CDS fabG8 NC_003155.4 8367774 8368535 D PF00106: short chain dehydrogenase; 3-oxoacyl-ACP reductase 8367774..8368535 Streptomyces avermitilis MA-4680 1211644 NP_828185.1 CDS fabG NC_003155.4 8368553 8369314 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 8368553..8369314 Streptomyces avermitilis MA-4680 1217221 NP_828186.1 CDS SAV_7010 NC_003155.4 8369462 8371084 D PF00496: Bacterial extracellular solute-binding proteins, family 5 Middle; lipoprotein oligopeptide binding protein 8369462..8371084 Streptomyces avermitilis MA-4680 1217222 NP_828187.1 CDS ung2 NC_003155.4 8371165 8371848 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 8371165..8371848 Streptomyces avermitilis MA-4680 1211645 NP_828188.1 CDS SAV_7012 NC_003155.4 8371980 8372630 D hypothetical protein 8371980..8372630 Streptomyces avermitilis MA-4680 1217223 NP_828189.1 CDS SAV_7013 NC_003155.4 8373001 8373465 R lipoprotein complement(8373001..8373465) Streptomyces avermitilis MA-4680 1217224 NP_828190.1 CDS SAV_7014 NC_003155.4 8373588 8374100 R PF04978: Protein of unknown function (DUF664); hypothetical protein complement(8373588..8374100) Streptomyces avermitilis MA-4680 1217225 NP_828191.1 CDS SAV_7015 NC_003155.4 8374210 8375115 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 8374210..8375115 Streptomyces avermitilis MA-4680 1217226 NP_828192.1 CDS SAV_7016 NC_003155.4 8375039 8376613 R PF00795: Carbon-nitrogen hydrolase; apolipoprotein N-acyltransferase complement(8375039..8376613) Streptomyces avermitilis MA-4680 1217227 NP_828193.1 CDS SAV_7017 NC_003155.4 8376702 8377169 R hypothetical protein complement(8376702..8377169) Streptomyces avermitilis MA-4680 1217228 NP_828194.1 CDS SAV_7018 NC_003155.4 8377344 8378360 D PF00296: Luciferase-like monooxygenase; monooxygenase 8377344..8378360 Streptomyces avermitilis MA-4680 1217229 NP_828195.1 CDS SAV_7019 NC_003155.4 8378431 8379291 R PF03631: Ribonuclease BN-like family; hypothetical protein complement(8378431..8379291) Streptomyces avermitilis MA-4680 1217230 NP_828196.1 CDS SAV_7020 NC_003155.4 8379743 8380042 R hypothetical protein complement(8379743..8380042) Streptomyces avermitilis MA-4680 1217231 NP_828197.1 CDS uppP NC_003155.4 8380573 8381448 R phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(8380573..8381448) Streptomyces avermitilis MA-4680 1217232 NP_828198.1 CDS SAV_7022 NC_003155.4 8381768 8383210 D PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase 8381768..8383210 Streptomyces avermitilis MA-4680 1217233 NP_828199.1 CDS SAV_7023 NC_003155.4 8383207 8384142 D hypothetical protein 8383207..8384142 Streptomyces avermitilis MA-4680 1217234 NP_828200.1 CDS SAV_7024 NC_003155.4 8384136 8384900 D hypothetical protein 8384136..8384900 Streptomyces avermitilis MA-4680 1217235 NP_828201.1 CDS SAV_7025 NC_003155.4 8384977 8385447 R transcriptional regulator complement(8384977..8385447) Streptomyces avermitilis MA-4680 1217236 NP_828202.1 CDS fadA6 NC_003155.4 8385638 8386807 D PF00108: Thiolase, N-terminal domain; 3-ketoacyl-CoA thiolase 8385638..8386807 Streptomyces avermitilis MA-4680 1211646 NP_828203.1 CDS SAV_7027 NC_003155.4 8386812 8387621 R PF00597: DedA family; hypothetical protein complement(8386812..8387621) Streptomyces avermitilis MA-4680 1217237 NP_828204.1 CDS tuf2 NC_003155.4 8388106 8389278 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 8388106..8389278 Streptomyces avermitilis MA-4680 1211647 NP_828205.1 CDS SAV_7029 NC_003155.4 8389436 8390281 D hypothetical protein 8389436..8390281 Streptomyces avermitilis MA-4680 1217238 NP_828206.1 CDS SAV_7030 NC_003155.4 8390243 8391586 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(8390243..8391586) Streptomyces avermitilis MA-4680 1217239 NP_828207.1 CDS SAV_7031 NC_003155.4 8391768 8392808 R hypothetical protein complement(8391768..8392808) Streptomyces avermitilis MA-4680 1217240 NP_828208.1 CDS SAV_7032 NC_003155.4 8392875 8393843 R hypothetical protein complement(8392875..8393843) Streptomyces avermitilis MA-4680 1217241 NP_828209.1 CDS SAV_7033 NC_003155.4 8393930 8394367 D hypothetical protein 8393930..8394367 Streptomyces avermitilis MA-4680 1217242 NP_828210.1 CDS SAV_7034 NC_003155.4 8394449 8394994 R PF05257: CHAP domain; hypothetical protein complement(8394449..8394994) Streptomyces avermitilis MA-4680 1217243 NP_828211.1 CDS SAV_7035 NC_003155.4 8395028 8396659 R PF00474: Sodium:solute symporter family; sodium:solute symporter complement(8395028..8396659) Streptomyces avermitilis MA-4680 1217244 NP_828212.1 CDS SAV_7036 NC_003155.4 8396656 8397066 R PF04341: Protein of unknown function, DUF485; hypothetical protein complement(8396656..8397066) Streptomyces avermitilis MA-4680 1217245 NP_828213.1 CDS SAV_7037 NC_003155.4 8397699 8398349 D PF00597: DedA family; integral membrane protein 8397699..8398349 Streptomyces avermitilis MA-4680 1217246 NP_828214.1 CDS SAV_7038 NC_003155.4 8398353 8398889 R PF00132: Bacterial transferase hexapeptide (three repeats); siderophore binding protein complement(8398353..8398889) Streptomyces avermitilis MA-4680 1217247 NP_828215.1 CDS SAV_7039 NC_003155.4 8399056 8399820 D PF00132: Bacterial transferase hexapeptide (three repeats); sugar acetyltransferase 8399056..8399820 Streptomyces avermitilis MA-4680 1217248 NP_828216.1 CDS SAV_7040 NC_003155.4 8399834 8400700 R PF00892: Integral membrane protein DUF6; hypothetical protein complement(8399834..8400700) Streptomyces avermitilis MA-4680 1217249 NP_828217.1 CDS SAV_7041 NC_003155.4 8400761 8401366 D transcriptional regulatory protein 8400761..8401366 Streptomyces avermitilis MA-4680 1217250 NP_828218.1 CDS SAV_7042 NC_003155.4 8401410 8401964 D PF04073: YbaK / prolyl-tRNA synthetases associated domain; hypothetical protein 8401410..8401964 Streptomyces avermitilis MA-4680 1217251 NP_828219.1 CDS SAV_7043 NC_003155.4 8402020 8403195 R PF01545: Cation efflux family; cation efflux system protein complement(8402020..8403195) Streptomyces avermitilis MA-4680 1217252 NP_828220.1 CDS SAV_7044 NC_003155.4 8403273 8403650 D transcription regulator ArsR 8403273..8403650 Streptomyces avermitilis MA-4680 1217253 NP_828221.1 CDS SAV_7045 NC_003155.4 8403809 8404369 R reductase complement(8403809..8404369) Streptomyces avermitilis MA-4680 1217254 NP_828222.1 CDS SAV_7046 NC_003155.4 8404483 8405154 D TetR family transcriptional regulator 8404483..8405154 Streptomyces avermitilis MA-4680 1217255 NP_828223.1 CDS SAV_7047 NC_003155.4 8405182 8405733 D PF04978: Protein of unknown function (DUF664); hypothetical protein 8405182..8405733 Streptomyces avermitilis MA-4680 1217256 NP_828224.1 CDS SAV_7048 NC_003155.4 8405794 8406909 D PF01545: Cation efflux family; cation efflux system protein 8405794..8406909 Streptomyces avermitilis MA-4680 1217257 NP_828225.1 CDS SAV_7049 NC_003155.4 8407094 8407501 R PF02629: CoA binding domain; hypothetical protein complement(8407094..8407501) Streptomyces avermitilis MA-4680 1217258 NP_828226.1 CDS SAV_7050 NC_003155.4 8407591 8408403 D hypothetical protein 8407591..8408403 Streptomyces avermitilis MA-4680 1217259 NP_828227.1 CDS SAV_7051 NC_003155.4 8408400 8408948 D PF00300: Phosphoglycerate mutase family; hypothetical protein 8408400..8408948 Streptomyces avermitilis MA-4680 1217260 NP_828228.1 CDS SAV_7052 NC_003155.4 8408996 8410972 R PF00324: Amino acid permease; amino acid transporter complement(8408996..8410972) Streptomyces avermitilis MA-4680 1217261 NP_828229.1 CDS SAV_7053 NC_003155.4 8411271 8411897 D PF01205: Uncharacterized protein family UPF0029; hypothetical protein 8411271..8411897 Streptomyces avermitilis MA-4680 1217262 NP_828230.1 CDS SAV_7054 NC_003155.4 8412224 8413720 D PF00270: DEAD/DEAH box helicase; ATP-dependent RNA helicase 8412224..8413720 Streptomyces avermitilis MA-4680 1217263 NP_828231.1 CDS sbcD NC_003155.4 8413967 8415130 D PF00149: Calcineurin-like phosphoesterase; exonuclease 8413967..8415130 Streptomyces avermitilis MA-4680 1211648 NP_828232.1 CDS sbcC NC_003155.4 8415198 8418197 D PF02463: RecF/RecN/SMC N terminal domain; exonuclease 8415198..8418197 Streptomyces avermitilis MA-4680 1211649 NP_828233.1 CDS SAV_7057 NC_003155.4 8418216 8418662 R transcription regulator AsnC complement(8418216..8418662) Streptomyces avermitilis MA-4680 1217264 NP_828234.1 CDS SAV_7058 NC_003155.4 8418709 8419395 D PF00581: Rhodanese-like domain; hypothetical protein 8418709..8419395 Streptomyces avermitilis MA-4680 1217265 NP_828235.1 CDS SAV_7059 NC_003155.4 8419484 8419708 D hypothetical protein 8419484..8419708 Streptomyces avermitilis MA-4680 1217266 NP_828236.1 CDS SAV_7060 NC_003155.4 8419839 8421530 R PF05960: Bacterial protein of unknown function (DUF885); hypothetical protein complement(8419839..8421530) Streptomyces avermitilis MA-4680 1217267 NP_828237.1 CDS SAV_7061 NC_003155.4 8421593 8422057 R transcription regulator AsnC complement(8421593..8422057) Streptomyces avermitilis MA-4680 1217268 NP_828238.1 CDS mgl NC_003155.4 8422223 8423464 D methionine gamma lyase 8422223..8423464 Streptomyces avermitilis MA-4680 1211650 NP_828239.1 CDS SAV_7063 NC_003155.4 8423663 8425096 R PF00583: Acetyltransferase (GNAT) family; hypothetical protein complement(8423663..8425096) Streptomyces avermitilis MA-4680 1217269 NP_828240.1 CDS phoD2 NC_003155.4 8425448 8427115 R alkaline phosphatase complement(8425448..8427115) Streptomyces avermitilis MA-4680 1217270 NP_828241.1 CDS SAV_7065 NC_003155.4 8427289 8428776 R GntR family transcriptional regulator complement(8427289..8428776) Streptomyces avermitilis MA-4680 1217271 NP_828242.1 CDS SAV_7066 NC_003155.4 8428851 8430017 D PF00892: Integral membrane protein DUF6; integral membrane protein 8428851..8430017 Streptomyces avermitilis MA-4680 1217272 NP_828243.1 CDS SAV_7067 NC_003155.4 8429733 8430656 R PF00561: alpha/beta hydrolase fold; hydrolase complement(8429733..8430656) Streptomyces avermitilis MA-4680 1217273 NP_828244.1 CDS sig55 NC_003155.4 8430823 8431707 D ECF subfamily RNA polymerase sigma factor 8430823..8431707 Streptomyces avermitilis MA-4680 1211651 NP_828245.1 CDS SAV_7069 NC_003155.4 8431958 8432719 D GntR family transcriptional regulator 8431958..8432719 Streptomyces avermitilis MA-4680 1217274 NP_828246.1 CDS SAV_7070 NC_003155.4 8432946 8434103 R transcriptional regulator complement(8432946..8434103) Streptomyces avermitilis MA-4680 1217275 NP_828247.1 CDS SAV_7071 NC_003155.4 8434203 8434865 R two-component system response regulator complement(8434203..8434865) Streptomyces avermitilis MA-4680 1217276 NP_828248.1 CDS SAV_7072 NC_003155.4 8434880 8436058 R two-component system sensor kinase complement(8434880..8436058) Streptomyces avermitilis MA-4680 1217277 NP_828249.1 CDS SAV_7073 NC_003155.4 8436167 8437093 D ABC transporter ATP-binding protein 8436167..8437093 Streptomyces avermitilis MA-4680 1217278 NP_828250.1 CDS SAV_7074 NC_003155.4 8437097 8437819 D ABC transporter permease 8437097..8437819 Streptomyces avermitilis MA-4680 1217279 NP_828251.1 CDS SAV_7075 NC_003155.4 8437877 8438317 D hypothetical protein 8437877..8438317 Streptomyces avermitilis MA-4680 1217280 NP_828252.1 CDS mug NC_003155.4 8438343 8438783 R G/U mismatch-specific DNA glycosylase complement(8438343..8438783) Streptomyces avermitilis MA-4680 1211652 NP_828253.1 CDS purB NC_003155.4 8438888 8440327 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(8438888..8440327) Streptomyces avermitilis MA-4680 1211653 NP_828254.1 CDS SAV_7078 NC_003155.4 8440387 8440737 R hypothetical protein complement(8440387..8440737) Streptomyces avermitilis MA-4680 1217281 NP_828255.1 CDS SAV_7079 NC_003155.4 8440759 8441541 R PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein complement(8440759..8441541) Streptomyces avermitilis MA-4680 1217282 NP_828256.1 CDS SAV_7080 NC_003155.4 8441839 8442852 R PF01595: Domain of unknown function DUF21; integral membrane protein complement(8441839..8442852) Streptomyces avermitilis MA-4680 1217283 NP_828257.1 CDS SAV_7081 NC_003155.4 8442849 8444195 R PF01595: Domain of unknown function DUF21; integral membrane protein complement(8442849..8444195) Streptomyces avermitilis MA-4680 1217284 NP_828258.1 CDS SAV_7082 NC_003155.4 8444344 8444769 R PF00583: Acetyltransferase (GNAT) family; acetyltransferase complement(8444344..8444769) Streptomyces avermitilis MA-4680 1217285 NP_828259.1 CDS SAV_7083 NC_003155.4 8444891 8445781 R Rif11-like protein complement(8444891..8445781) Streptomyces avermitilis MA-4680 1217286 NP_828260.1 CDS SAV_7084 NC_003155.4 8445829 8448396 R ABC transporter permease complement(8445829..8448396) Streptomyces avermitilis MA-4680 1217287 NP_828261.1 CDS SAV_7085 NC_003155.4 8448408 8449292 R ABC transporter ATP-binding protein complement(8448408..8449292) Streptomyces avermitilis MA-4680 1217288 NP_828262.1 CDS SAV_7086 NC_003155.4 8449521 8449760 D hypothetical protein 8449521..8449760 Streptomyces avermitilis MA-4680 1217289 NP_828263.1 CDS SAV_7087 NC_003155.4 8449765 8450139 D hypothetical protein 8449765..8450139 Streptomyces avermitilis MA-4680 1217290 NP_828264.1 CDS SAV_7088 NC_003155.4 8450156 8450842 R PF01209: ubiE/COQ5 methyltransferase family; hypothetical protein complement(8450156..8450842) Streptomyces avermitilis MA-4680 1217291 NP_828265.1 CDS lpsA1 NC_003155.4 8450955 8451641 R lipase complement(8450955..8451641) Streptomyces avermitilis MA-4680 1217292 NP_828266.1 CDS lpsR NC_003155.4 8451756 8453981 D lpsA1 transcriptional activator 8451756..8453981 Streptomyces avermitilis MA-4680 1211654 NP_828267.1 CDS bioD NC_003155.4 8453985 8454701 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(8453985..8454701) Streptomyces avermitilis MA-4680 1211655 NP_828268.1 CDS bioA NC_003155.4 8454703 8456016 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(8454703..8456016) Streptomyces avermitilis MA-4680 1211656 NP_828269.1 CDS bioB NC_003155.4 8455985 8457151 R catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase complement(8455985..8457151) Streptomyces avermitilis MA-4680 1211657 NP_828270.1 CDS bioF NC_003155.4 8457312 8458469 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 8457312..8458469 Streptomyces avermitilis MA-4680 1211658 NP_828271.1 CDS SAV_7095 NC_003155.4 8458491 8458670 R PF04149: Domain of unknown function (DUF397); hypothetical protein complement(8458491..8458670) Streptomyces avermitilis MA-4680 1217293 NP_828272.1 CDS SAV_7096 NC_003155.4 8458736 8459587 R DNA-binding protein complement(8458736..8459587) Streptomyces avermitilis MA-4680 1217294 NP_828273.1 CDS SAV_7097 NC_003155.4 8459835 8460293 D regulatory protein 8459835..8460293 Streptomyces avermitilis MA-4680 1217295 NP_828274.1 CDS SAV_7098 NC_003155.4 8460552 8461106 R hypothetical protein complement(8460552..8461106) Streptomyces avermitilis MA-4680 1217296 NP_828275.1 CDS SAV_7099 NC_003155.4 8461155 8461628 R Seems to have no N-terminal signal sequence; NLP/P60-family protein complement(8461155..8461628) Streptomyces avermitilis MA-4680 1217297 NP_828276.1 CDS SAV_7100 NC_003155.4 8462164 8462472 R hypothetical protein complement(8462164..8462472) Streptomyces avermitilis MA-4680 1217298 NP_828277.1 CDS clpP3 NC_003155.4 8462480 8463115 R PF00574: Clp protease; ATP-dependent Clp protease proteolytic subunit 2 complement(8462480..8463115) Streptomyces avermitilis MA-4680 1211659 NP_828278.1 CDS SAV_7102 NC_003155.4 8463350 8463625 D PF02604: Phd_YefM; hypothetical protein 8463350..8463625 Streptomyces avermitilis MA-4680 1217299 NP_828279.1 CDS SAV_7103 NC_003155.4 8464059 8464340 D hypothetical protein 8464059..8464340 Streptomyces avermitilis MA-4680 1217300 NP_828280.1 CDS ureA NC_003155.4 8464532 8464834 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 8464532..8464834 Streptomyces avermitilis MA-4680 1211660 NP_828281.1 CDS ureB NC_003155.4 8464852 8465163 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 8464852..8465163 Streptomyces avermitilis MA-4680 1211661 NP_828282.1 CDS ureC NC_003155.4 8465156 8466877 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 8465156..8466877 Streptomyces avermitilis MA-4680 1211662 NP_828283.1 CDS ureF NC_003155.4 8466877 8467551 D PF01730: UreF; urease accessroy protein 8466877..8467551 Streptomyces avermitilis MA-4680 1211663 NP_828284.1 CDS ureG NC_003155.4 8467570 8468253 D PF02492: CobW/HypB/UreG, nucleotide-binding domain; urease accessory protein 8467570..8468253 Streptomyces avermitilis MA-4680 1211664 NP_828285.1 CDS ureD NC_003155.4 8468250 8469008 D PF01774: UreD urease accessory protein; urease accessory protein 8468250..8469008 Streptomyces avermitilis MA-4680 1211665 NP_828286.1 CDS SAV_7110 NC_003155.4 8469147 8470742 D PF00561: alpha/beta hydrolase fold; tripeptidylaminopeptidase 8469147..8470742 Streptomyces avermitilis MA-4680 1217301 NP_828287.1 CDS plsC6 NC_003155.4 8470813 8471538 R 1-acylglycerol-3-phosphate O-acyltransferase complement(8470813..8471538) Streptomyces avermitilis MA-4680 1211666 NP_828288.1 CDS rocD2 NC_003155.4 8471639 8472865 R ornithine aminotransferase complement(8471639..8472865) Streptomyces avermitilis MA-4680 1211667 NP_828289.1 CDS SAV_7113 NC_003155.4 8472862 8473731 R PF02274: Amidinotransferase; hypothetical protein complement(8472862..8473731) Streptomyces avermitilis MA-4680 1217302 NP_828290.1 CDS SAV_7114 NC_003155.4 8473808 8474311 R transcription regulator AsnC complement(8473808..8474311) Streptomyces avermitilis MA-4680 1217303 NP_828291.1 CDS SAV_7115 NC_003155.4 8474389 8475144 D regulatory protein 8474389..8475144 Streptomyces avermitilis MA-4680 1217304 NP_828292.1 CDS SAV_7116 NC_003155.4 8475158 8475517 D hypothetical protein 8475158..8475517 Streptomyces avermitilis MA-4680 1217305 NP_828293.1 CDS SAV_7117 NC_003155.4 8475522 8477249 D PF00474: Sodium:solute symporter family; transmembrane transport protein 8475522..8477249 Streptomyces avermitilis MA-4680 1217306 NP_828294.1 CDS lytS NC_003155.4 8477246 8478451 D two-component system sensor kinase 8477246..8478451 Streptomyces avermitilis MA-4680 1211668 NP_828295.1 CDS SAV_7119 NC_003155.4 8478645 8479382 R hypothetical protein complement(8478645..8479382) Streptomyces avermitilis MA-4680 1217307 NP_828296.1 CDS pkn31 NC_003155.4 8478832 8480910 R serine/threonine protein kinase complement(8478832..8480910) Streptomyces avermitilis MA-4680 1211669 NP_828297.1 CDS SAV_7121 NC_003155.4 8480924 8482384 R PF04554: Extensin-like region; hypothetical protein complement(8480924..8482384) Streptomyces avermitilis MA-4680 1217308 NP_828298.1 CDS SAV_7122 NC_003155.4 8482495 8483448 R hypothetical protein complement(8482495..8483448) Streptomyces avermitilis MA-4680 1217309 NP_828299.1 CDS pfkA3 NC_003155.4 8483551 8484576 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(8483551..8484576) Streptomyces avermitilis MA-4680 1211670 NP_828300.1 CDS cobQ2 NC_003155.4 8484766 8485494 R PF07685: CobB/CobQ-like glutamine amidotransferase domain; glutamine amidotransferase complement(8484766..8485494) Streptomyces avermitilis MA-4680 1217310 NP_828301.1 CDS SAV_7125 NC_003155.4 8485517 8486755 R PF01225: Mur ligase family, catalytic domain; ligase complement(8485517..8486755) Streptomyces avermitilis MA-4680 1217311 NP_828302.1 CDS def2 NC_003155.4 8486898 8487458 D polypeptide deformylase 8486898..8487458 Streptomyces avermitilis MA-4680 1211671 NP_828303.1 CDS SAV_7127 NC_003155.4 8487586 8488284 R TetR family transcriptional regulator complement(8487586..8488284) Streptomyces avermitilis MA-4680 1217312 NP_828304.1 CDS fadE6 NC_003155.4 8488405 8489634 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 8488405..8489634 Streptomyces avermitilis MA-4680 1211672 NP_828305.1 CDS SAV_7129 NC_003155.4 8489671 8490198 R PF00190: Cupin; hypothetical protein complement(8489671..8490198) Streptomyces avermitilis MA-4680 1217313 NP_828306.1 CDS cyp25 NC_003155.4 8490207 8491421 R CYP158A3, adjacent to rpp; cytochrome P450 complement(8490207..8491421) Streptomyces avermitilis MA-4680 1211673 NP_828307.1 CDS rppA NC_003155.4 8491426 8492484 R PhlD homolog, PF02797: Chalcone and stilbene synthases, C-terminal domain; type III polyketide synthase complement(8491426..8492484) Streptomyces avermitilis MA-4680 1211674 NP_828308.1 CDS SAV_7132 NC_003155.4 8492643 8493359 D hypothetical protein 8492643..8493359 Streptomyces avermitilis MA-4680 1217314 NP_828309.1 CDS SAV_7133 NC_003155.4 8493375 8493614 R hypothetical protein complement(8493375..8493614) Streptomyces avermitilis MA-4680 1217315 NP_828310.1 CDS gabD1 NC_003155.4 8493640 8495034 R NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; succinic semialdehyde dehydrogenase complement(8493640..8495034) Streptomyces avermitilis MA-4680 1217316 NP_828311.1 CDS SAV_7135 NC_003155.4 8495108 8495572 R MutT-like protein complement(8495108..8495572) Streptomyces avermitilis MA-4680 1217317 NP_828312.1 CDS ligB NC_003155.4 8495569 8497107 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase complement(8495569..8497107) Streptomyces avermitilis MA-4680 1211675 NP_828313.1 CDS SAV_7137 NC_003155.4 8497137 8498126 R reductase complement(8497137..8498126) Streptomyces avermitilis MA-4680 1217318 NP_828314.1 CDS SAV_7138 NC_003155.4 8498183 8498803 D regulatory protein 8498183..8498803 Streptomyces avermitilis MA-4680 1217319 NP_828315.1 CDS SAV_7139 NC_003155.4 8498823 8499866 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 8498823..8499866 Streptomyces avermitilis MA-4680 1217320 NP_828316.1 CDS fadE16 NC_003155.4 8499863 8501044 D PF02770: Acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase 8499863..8501044 Streptomyces avermitilis MA-4680 1211676 NP_828317.1 CDS fadE21 NC_003155.4 8501023 8502153 D PF00441: Acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase 8501023..8502153 Streptomyces avermitilis MA-4680 1211677 NP_828318.1 CDS SAV_7142 NC_003155.4 8502328 8503188 D protein 8502328..8503188 Streptomyces avermitilis MA-4680 1217321 NP_828319.1 CDS SAV_7143 NC_003155.4 8503291 8503485 D hypothetical protein 8503291..8503485 Streptomyces avermitilis MA-4680 1217322 NP_828320.1 CDS SAV_7144 NC_003155.4 8503525 8504754 R protein complement(8503525..8504754) Streptomyces avermitilis MA-4680 1217323 NP_828321.1 CDS SAV_7145 NC_003155.4 8504830 8505198 R PF05610: Protein of unknown function (DUF779); hypothetical protein complement(8504830..8505198) Streptomyces avermitilis MA-4680 1217324 NP_828322.1 CDS SAV_7146 NC_003155.4 8505258 8506025 R PF07702: UbiC transcription regulator-associated; GntR family transcriptional regulator complement(8505258..8506025) Streptomyces avermitilis MA-4680 1217325 NP_828323.1 CDS iolD2 NC_003155.4 8506099 8507988 R inositol metabolism, PF00205: Thiamine pyrophosphate enzyme, central domain; IolD protein complement(8506099..8507988) Streptomyces avermitilis MA-4680 1211678 NP_828324.1 CDS iolB2 NC_003155.4 8507996 8508901 R inositol metabolism, PF06845: Myo-inositol catabolism protein IolB; IolB protein complement(8507996..8508901) Streptomyces avermitilis MA-4680 1217326 NP_828325.1 CDS SAV_7149 NC_003155.4 8508931 8509809 R PF07157: DNA circulation protein N-terminus; hypothetical protein complement(8508931..8509809) Streptomyces avermitilis MA-4680 1217327 NP_828326.1 CDS iolC2 NC_003155.4 8509835 8510791 R inositol metabolism, PF00294: pfkB family carbohydrate kinase; IolC protein complement(8509835..8510791) Streptomyces avermitilis MA-4680 1217328 NP_828327.1 CDS SAV_7151 NC_003155.4 8511099 8512118 D sugar ABC transporter substrate-binding protein 8511099..8512118 Streptomyces avermitilis MA-4680 1217329 NP_828328.1 CDS SAV_7152 NC_003155.4 8512124 8513197 D sugar ABC transporter permease 8512124..8513197 Streptomyces avermitilis MA-4680 1217330 NP_828329.1 CDS SAV_7153 NC_003155.4 8513207 8514118 D sugar ABC transporter ATP-binding protein 8513207..8514118 Streptomyces avermitilis MA-4680 1217331 NP_828330.1 CDS iolE2 NC_003155.4 8514120 8515022 D inositol metaqbolism, PF06960: Myo-inositol catabolism protein N-terminus; IolE protein 8514120..8515022 Streptomyces avermitilis MA-4680 1217332 NP_828331.1 CDS SAV_7155 NC_003155.4 8515251 8516435 R PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase complement(8515251..8516435) Streptomyces avermitilis MA-4680 1217333 NP_828332.1 CDS SAV_7156 NC_003155.4 8516580 8517596 D PF00532: Periplasmic binding proteins and sugar binding domain of the LacI family; LacI family transcriptional regulator 8516580..8517596 Streptomyces avermitilis MA-4680 1217334 NP_828333.1 CDS SAV_7157 NC_003155.4 8517907 8518266 D PF01740: STAS domain; hypothetical protein 8517907..8518266 Streptomyces avermitilis MA-4680 1217335 NP_828334.1 CDS prsR NC_003155.4 8518263 8519195 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; regulator of sigma factor 8518263..8519195 Streptomyces avermitilis MA-4680 1217336 NP_828335.1 CDS gabD3 NC_003155.4 8519323 8520771 R succinate-semialdehyde dehydrogenase, NADP-dependent complement(8519323..8520771) Streptomyces avermitilis MA-4680 1211679 NP_828336.1 CDS SAV_7160 NC_003155.4 8521230 8522489 R aminotransferase complement(8521230..8522489) Streptomyces avermitilis MA-4680 1217337 NP_828337.1 CDS SAV_7161 NC_003155.4 8522760 8524415 D nrps4 gene cluster; regulatory protein 8522760..8524415 Streptomyces avermitilis MA-4680 1217338 NP_828338.1 CDS cysK3 NC_003155.4 8524485 8525567 R nrps4 gene cluster; cysteine synthase complement(8524485..8525567) Streptomyces avermitilis MA-4680 1211680 NP_828339.1 CDS arcB4 NC_003155.4 8525756 8526826 R nrps4 gene cluster; ornithine cyclodeaminase complement(8525756..8526826) Streptomyces avermitilis MA-4680 1211681 NP_828340.1 CDS SAV_7164 NC_003155.4 8526823 8527794 R nrps4 gene cluster; SyrP-like protein complement(8526823..8527794) Streptomyces avermitilis MA-4680 1217339 NP_828341.1 CDS nrps4 NC_003155.4 8527980 8530697 R nrps4 gene cluster; non-ribosomal peptide synthetase complement(8527980..8530697) Streptomyces avermitilis MA-4680 1217340 NP_828342.1 CDS SAV_7166 NC_003155.4 8531505 8533463 D amidase 8531505..8533463 Streptomyces avermitilis MA-4680 1217341 NP_828343.1 CDS SAV_7167 NC_003155.4 8534240 8534830 R TetR family transcriptional regulator complement(8534240..8534830) Streptomyces avermitilis MA-4680 1217342 NP_828344.1 CDS SAV_7168 NC_003155.4 8534873 8535412 D PF01361: Tautomerase enzyme; hypothetical protein 8534873..8535412 Streptomyces avermitilis MA-4680 1217343 NP_828345.1 CDS SAV_7169 NC_003155.4 8535405 8536415 D PF00107: Zinc-binding dehydrogenase; dehydrogenase 8535405..8536415 Streptomyces avermitilis MA-4680 1217344 NP_828346.1 CDS SAV_7170 NC_003155.4 8536960 8537487 D hypothetical protein 8536960..8537487 Streptomyces avermitilis MA-4680 1217345 NP_828347.1 CDS SAV_7171 NC_003155.4 8537697 8538272 R hypothetical protein complement(8537697..8538272) Streptomyces avermitilis MA-4680 1217346 NP_828348.1 CDS prpJ7 NC_003155.4 8538378 8540762 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(8538378..8540762) Streptomyces avermitilis MA-4680 1217347 NP_828349.1 CDS SAV_7173 NC_003155.4 8541622 8541942 D hypothetical protein 8541622..8541942 Streptomyces avermitilis MA-4680 1217348 NP_828350.1 CDS SAV_7174 NC_003155.4 8542083 8542616 D hypothetical protein 8542083..8542616 Streptomyces avermitilis MA-4680 1217349 NP_828351.1 CDS SAV_7175 NC_003155.4 8542664 8542870 R hypothetical protein complement(8542664..8542870) Streptomyces avermitilis MA-4680 1217350 NP_828352.1 CDS SAV_7176 NC_003155.4 8543264 8543524 R hypothetical protein complement(8543264..8543524) Streptomyces avermitilis MA-4680 1217351 NP_828353.1 CDS thcA NC_003155.4 8543834 8545357 R PF00171: Aldehyde dehydrogenase family; aldehyde dehydrogenase complement(8543834..8545357) Streptomyces avermitilis MA-4680 1211682 NP_828354.1 CDS SAV_7178 NC_003155.4 8545481 8546770 R transcriptional regulator complement(8545481..8546770) Streptomyces avermitilis MA-4680 1217352 NP_828355.1 CDS amiA2 NC_003155.4 8546880 8547479 R PF01510: N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase complement(8546880..8547479) Streptomyces avermitilis MA-4680 1217353 NP_828356.1 CDS xylR NC_003155.4 8548061 8549299 R xylose repressor complement(8548061..8549299) Streptomyces avermitilis MA-4680 1211683 NP_828357.2 CDS xylB1 NC_003155.4 8549337 8550782 R PF00370: FGGY family of carbohydrate kinases, N-terminal domain; xylulose kinase complement(8549337..8550782) Streptomyces avermitilis MA-4680 1211684 NP_828358.1 CDS xylA NC_003155.4 8550993 8552159 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 8550993..8552159 Streptomyces avermitilis MA-4680 1211685 NP_828359.1 CDS SAV_7183 NC_003155.4 8552704 8553312 D PF04886: PT repeat; hypothetical protein 8552704..8553312 Streptomyces avermitilis MA-4680 1217354 NP_828360.1 CDS pks4 NC_003155.4 8553602 8558155 R pks4 gene cluster; modular polyketide synthase complement(8553602..8558155) Streptomyces avermitilis MA-4680 1217355 NP_828361.1 CDS SAV_7185 NC_003155.4 8559018 8560301 R pks4 gene cluster, PF03033: Glycosyltransferase family 28 N-terminal domain; UDP-glucose:sterol glucosyltransferase complement(8559018..8560301) Streptomyces avermitilis MA-4680 1217356 NP_828362.1 CDS cyp26 NC_003155.4 8560411 8561604 R CYP105R1, pks4 gene cluster; cytochrome P450 hydroxylase complement(8560411..8561604) Streptomyces avermitilis MA-4680 1211686 NP_828363.1 CDS SAV_7187 NC_003155.4 8561754 8563319 D PF07690: Major Facilitator Superfamily; transmembrane efflux protein 8561754..8563319 Streptomyces avermitilis MA-4680 1217357 NP_828364.1 CDS SAV_7188 NC_003155.4 8563465 8564472 R PF01408: Oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase complement(8563465..8564472) Streptomyces avermitilis MA-4680 1217358 NP_828365.1 CDS SAV_7189 NC_003155.4 8564504 8565325 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(8564504..8565325) Streptomyces avermitilis MA-4680 1217359 NP_828366.1 CDS SAV_7190 NC_003155.4 8565339 8566514 R PF05721: Phytanoyl-CoA dioxygenase (PhyH); hypothetical protein complement(8565339..8566514) Streptomyces avermitilis MA-4680 1217360 NP_828367.1 CDS SAV_7191 NC_003155.4 8566612 8567661 D DNA-binding protein 8566612..8567661 Streptomyces avermitilis MA-4680 1217361 NP_828368.1 CDS SAV_7192 NC_003155.4 8567815 8568180 D hypothetical protein 8567815..8568180 Streptomyces avermitilis MA-4680 1217362 NP_828369.1 CDS ppx3 NC_003155.4 8568544 8569554 R PF02541: Ppx/GppA phosphatase family; exopolyphosphatase complement(8568544..8569554) Streptomyces avermitilis MA-4680 1217363 NP_828370.1 CDS SAV_7194 NC_003155.4 8569752 8570417 D methyltransferase 8569752..8570417 Streptomyces avermitilis MA-4680 1217364 NP_828371.1 CDS SAV_7195 NC_003155.4 8570401 8570610 D hypothetical protein 8570401..8570610 Streptomyces avermitilis MA-4680 1217365 NP_828372.1 CDS SAV_7196 NC_003155.4 8570607 8571629 D hypothetical protein 8570607..8571629 Streptomyces avermitilis MA-4680 1217366 NP_828373.1 CDS rdh NC_003155.4 8571613 8572494 D ribitol dehydrogenase 8571613..8572494 Streptomyces avermitilis MA-4680 1211687 NP_828374.1 CDS SAV_7198 NC_003155.4 8572537 8573436 R PF00561: alpha/beta hydrolase fold; hydrolase complement(8572537..8573436) Streptomyces avermitilis MA-4680 1217367 NP_828375.1 CDS SAV_7199 NC_003155.4 8573497 8573883 D PF01638: Transcriptional regulator; transcriptional regulator 8573497..8573883 Streptomyces avermitilis MA-4680 1217368 NP_828376.1 CDS SAV_7200 NC_003155.4 8574316 8575161 D PF00230: Major intrinsic protein; transport integral membrane protein 8574316..8575161 Streptomyces avermitilis MA-4680 1217369 NP_828377.1 CDS glpK NC_003155.4 8575186 8576703 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 8575186..8576703 Streptomyces avermitilis MA-4680 1211688 NP_828378.1 CDS SAV_7202 NC_003155.4 8577139 8577666 R hypothetical protein complement(8577139..8577666) Streptomyces avermitilis MA-4680 1217370 NP_828379.1 CDS SAV_7203 NC_003155.4 8577945 8579495 D PF00266: Aminotransferase class-V; hypothetical protein 8577945..8579495 Streptomyces avermitilis MA-4680 1217371 NP_828380.1 CDS SAV_7204 NC_003155.4 8579581 8581101 D hypothetical protein 8579581..8581101 Streptomyces avermitilis MA-4680 1217372 NP_828381.1 CDS thiD NC_003155.4 8581221 8582018 R phosphomethylpyrimidine kinase complement(8581221..8582018) Streptomyces avermitilis MA-4680 1211690 NP_828382.1 CDS SAV_7206 NC_003155.4 8582015 8583430 R cytosine permease complement(8582015..8583430) Streptomyces avermitilis MA-4680 1217373 NP_828383.1 CDS SAV_7207 NC_003155.4 8583610 8584947 R PF03372: Endonuclease/Exonuclease/phosphatase family; hypothetical protein complement(8583610..8584947) Streptomyces avermitilis MA-4680 1217374 NP_828384.1 CDS SAV_7208 NC_003155.4 8585756 8586712 D ABC transporter permease 8585756..8586712 Streptomyces avermitilis MA-4680 1217375 NP_828385.1 CDS SAV_7209 NC_003155.4 8586709 8587494 D ABC transporter ATP-binding protein 8586709..8587494 Streptomyces avermitilis MA-4680 1217376 NP_828386.1 CDS SAV_7210 NC_003155.4 8587567 8588592 D ABC transporter substrate-binding protein 8587567..8588592 Streptomyces avermitilis MA-4680 1217377 NP_828387.1 CDS SAV_7211 NC_003155.4 8588620 8589378 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8588620..8589378 Streptomyces avermitilis MA-4680 1217378 NP_828388.1 CDS SAV_7212 NC_003155.4 8589594 8590856 D FMNH2-utilizing oxygenase 8589594..8590856 Streptomyces avermitilis MA-4680 1217379 NP_828389.1 CDS SAV_7213 NC_003155.4 8590876 8592252 D FMNH2-utilizing oxygenase 8590876..8592252 Streptomyces avermitilis MA-4680 1217380 NP_828390.1 CDS icdA NC_003155.4 8592489 8594708 R isocitrate dehydrogenase complement(8592489..8594708) Streptomyces avermitilis MA-4680 1211691 NP_828391.1 CDS SAV_7215 NC_003155.4 8595290 8596465 R PF00924: Mechanosensitive ion channel; integral membrane protein complement(8595290..8596465) Streptomyces avermitilis MA-4680 1217381 NP_828392.1 CDS echA15 NC_003155.4 8596791 8597558 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(8596791..8597558) Streptomyces avermitilis MA-4680 1211692 NP_828393.1 CDS SAV_7217 NC_003155.4 8597655 8598521 R PF03706: Uncharacterised protein family (UPF0104); hypothetical protein complement(8597655..8598521) Streptomyces avermitilis MA-4680 1217382 NP_828394.1 CDS SAV_7218 NC_003155.4 8598813 8600720 D ABC transporter ATP-binding protein 8598813..8600720 Streptomyces avermitilis MA-4680 1217383 NP_828395.1 CDS pbp12 NC_003155.4 8601038 8603263 D PF00912: Transglycosylase; penicillin-binding protein 8601038..8603263 Streptomyces avermitilis MA-4680 1211693 NP_828396.1 CDS SAV_7220 NC_003155.4 8603412 8604638 D hypothetical protein 8603412..8604638 Streptomyces avermitilis MA-4680 1217384 NP_828397.1 CDS SAV_7221 NC_003155.4 8604802 8605935 D hypothetical protein 8604802..8605935 Streptomyces avermitilis MA-4680 1217385 NP_828398.1 CDS SAV_7222 NC_003155.4 8606063 8607682 D hypothetical protein 8606063..8607682 Streptomyces avermitilis MA-4680 1217386 NP_828399.1 CDS SAV_7223 NC_003155.4 8607682 8609019 D hypothetical protein 8607682..8609019 Streptomyces avermitilis MA-4680 1217387 NP_828400.1 CDS SAV_7224 NC_003155.4 8609016 8613215 D PF01576: Myosin tail; hypothetical protein 8609016..8613215 Streptomyces avermitilis MA-4680 1217388 NP_828401.1 CDS SAV_7225 NC_003155.4 8613212 8614549 D hypothetical protein 8613212..8614549 Streptomyces avermitilis MA-4680 1217389 NP_828402.1 CDS SAV_7226 NC_003155.4 8614617 8615825 R PF00106: short chain dehydrogenase; short chain dehydrogenase complement(8614617..8615825) Streptomyces avermitilis MA-4680 1217390 NP_828403.1 CDS SAV_7227 NC_003155.4 8616415 8616951 D hypothetical protein 8616415..8616951 Streptomyces avermitilis MA-4680 1217391 NP_828404.1 CDS SAV_7228 NC_003155.4 8616956 8619310 R PF05976: Bacterial membrane protein of unknown function (DUF893); hypothetical protein complement(8616956..8619310) Streptomyces avermitilis MA-4680 1217392 NP_828405.1 CDS SAV_7229 NC_003155.4 8619439 8620614 R PF00107: Zinc-binding dehydrogenase; glutathione-independent formaldehyde dehydrogenase complement(8619439..8620614) Streptomyces avermitilis MA-4680 1217393 NP_828406.1 CDS SAV_7230 NC_003155.4 8620952 8622373 R hypothetical protein complement(8620952..8622373) Streptomyces avermitilis MA-4680 1217394 NP_828407.1 CDS pfpI2 NC_003155.4 8622783 8623439 R PF01965: DJ-1/PfpI family; intracellular protease/amidase complement(8622783..8623439) Streptomyces avermitilis MA-4680 1217395 NP_828408.1 CDS SAV_7232 NC_003155.4 8623814 8624419 R hypothetical protein complement(8623814..8624419) Streptomyces avermitilis MA-4680 1217396 NP_828409.1 CDS SAV_7233 NC_003155.4 8624703 8625548 R PF00248: Aldo/keto reductase family; oxidoreductase complement(8624703..8625548) Streptomyces avermitilis MA-4680 1217397 NP_828410.1 CDS SAV_7234 NC_003155.4 8625651 8626844 R PF07690: Major Facilitator Superfamily; multidrug efflux protein complement(8625651..8626844) Streptomyces avermitilis MA-4680 1217398 NP_828411.1 CDS SAV_7235 NC_003155.4 8627105 8627995 D LysR family transcriptional regulator 8627105..8627995 Streptomyces avermitilis MA-4680 1217399 NP_828412.1 CDS SAV_7236 NC_003155.4 8628137 8629918 R PF05651: Putative sugar diacid recognition; hypothetical protein complement(8628137..8629918) Streptomyces avermitilis MA-4680 1217400 NP_828413.1 CDS dnaK NC_003155.4 8630200 8632101 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 8630200..8632101 Streptomyces avermitilis MA-4680 1211694 NP_828414.1 CDS grpE2 NC_003155.4 8632110 8632721 D GrpE homologue 8632110..8632721 Streptomyces avermitilis MA-4680 1211695 NP_828415.1 CDS dnaJ2 NC_003155.4 8632728 8633681 D heat shock protein DnaJ 8632728..8633681 Streptomyces avermitilis MA-4680 1211696 NP_828416.1 CDS SAV_7240 NC_003155.4 8633678 8634085 D PF00376: MerR family regulatory protein; hypothetical protein 8633678..8634085 Streptomyces avermitilis MA-4680 1217401 NP_828417.1 CDS clpB2 NC_003155.4 8634076 8636715 D PF07724: ATPase family associated with various cellular activities (AAA); ATP-dependent Clp protease 8634076..8636715 Streptomyces avermitilis MA-4680 1211697 NP_828418.1 CDS trxA2 NC_003155.4 8636703 8637158 D thioredoxin 8636703..8637158 Streptomyces avermitilis MA-4680 1211698 NP_828419.1 CDS trxB2 NC_003155.4 8637391 8639241 D thioredoxin reductase 8637391..8639241 Streptomyces avermitilis MA-4680 1211699 NP_828420.1 CDS SAV_7244 NC_003155.4 8639255 8639617 D PF00011: Hsp20/alpha crystallin family; hypothetical protein 8639255..8639617 Streptomyces avermitilis MA-4680 1217402 NP_828421.1 CDS panD NC_003155.4 8640232 8640651 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 8640232..8640651 Streptomyces avermitilis MA-4680 1211700 NP_828422.1 CDS SAV_7246 NC_003155.4 8640688 8641032 D hypothetical protein 8640688..8641032 Streptomyces avermitilis MA-4680 1217403 NP_828423.1 CDS SAV_7247 NC_003155.4 8641002 8641742 D hypothetical protein 8641002..8641742 Streptomyces avermitilis MA-4680 1217404 NP_828424.1 CDS SAV_7248 NC_003155.4 8641813 8642034 D hypothetical protein 8641813..8642034 Streptomyces avermitilis MA-4680 1217405 NP_828425.1 CDS gnd3 NC_003155.4 8642147 8643586 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(8642147..8643586) Streptomyces avermitilis MA-4680 1211701 NP_828426.1 CDS SAV_7250 NC_003155.4 8643887 8645080 D PF01551: Peptidase family M23; peptidase 8643887..8645080 Streptomyces avermitilis MA-4680 1217406 NP_828427.1 CDS SAV_7251 NC_003155.4 8645070 8646197 R PF05653: Protein of unknown function (DUF803); hypothetical protein complement(8645070..8646197) Streptomyces avermitilis MA-4680 1217407 NP_828428.1 CDS SAV_7252 NC_003155.4 8646408 8647133 D PF06276: Ferric iron reductase protein FhuF; hypothetical protein 8646408..8647133 Streptomyces avermitilis MA-4680 1217408 NP_828429.1 CDS glgA2 NC_003155.4 8647207 8648358 D PF00534: Glycosyl transferases group 1; glycosyl transferase 8647207..8648358 Streptomyces avermitilis MA-4680 1211702 NP_828430.1 CDS glgC NC_003155.4 8648395 8649615 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 8648395..8649615 Streptomyces avermitilis MA-4680 1211703 NP_828431.1 CDS SAV_7255 NC_003155.4 8649736 8652069 D protein 8649736..8652069 Streptomyces avermitilis MA-4680 1217409 NP_828432.1 CDS SAV_7256 NC_003155.4 8652210 8653553 D PF03007: Uncharacterised protein family (UPF0089); hypothetical protein 8652210..8653553 Streptomyces avermitilis MA-4680 1217410 NP_828433.1 CDS SAV_7257 NC_003155.4 8653701 8655185 D PF00106: short chain dehydrogenase; dehydrogenase 8653701..8655185 Streptomyces avermitilis MA-4680 1217411 NP_828434.1 CDS SAV_7258 NC_003155.4 8655203 8655514 D hypothetical protein 8655203..8655514 Streptomyces avermitilis MA-4680 1217412 NP_828435.1 CDS fabG NC_003155.4 8655567 8656373 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(8655567..8656373) Streptomyces avermitilis MA-4680 1211704 NP_828436.1 CDS SAV_7260 NC_003155.4 8656399 8656947 R hypothetical protein complement(8656399..8656947) Streptomyces avermitilis MA-4680 1217413 NP_828437.1 CDS SAV_7261 NC_003155.4 8657747 8658229 D PF00583: Acetyltransferase (GNAT) family; acetyltransferase 8657747..8658229 Streptomyces avermitilis MA-4680 1217414 NP_828438.1 CDS SAV_7262 NC_003155.4 8658263 8660257 R hypothetical protein complement(8658263..8660257) Streptomyces avermitilis MA-4680 1217415 NP_828439.1 CDS SAV_7263 NC_003155.4 8660501 8661892 D ABC transporter substrate-binding protein 8660501..8661892 Streptomyces avermitilis MA-4680 1217416 NP_828440.1 CDS araP NC_003155.4 8661889 8662830 D L-arabinose ABC transporter permease 8661889..8662830 Streptomyces avermitilis MA-4680 1211705 NP_828441.1 CDS araQ NC_003155.4 8662827 8663702 D L-arabinose ABC transporter permease 8662827..8663702 Streptomyces avermitilis MA-4680 1211706 NP_828442.1 CDS SAV_7266 NC_003155.4 8663699 8665531 D PF02065: Melibiase; hypothetical protein 8663699..8665531 Streptomyces avermitilis MA-4680 1217417 NP_828443.1 CDS malR2 NC_003155.4 8665528 8666526 D LacI-family transcriptional regulator; MalR repressor protein 8665528..8666526 Streptomyces avermitilis MA-4680 1211707 NP_828444.1 CDS SAV_7268 NC_003155.4 8666657 8668534 D hypothetical protein 8666657..8668534 Streptomyces avermitilis MA-4680 1217418 NP_828445.1 CDS amiE1 NC_003155.4 8668562 8669926 R amidase complement(8668562..8669926) Streptomyces avermitilis MA-4680 1217419 NP_828446.1 CDS SAV_7270 NC_003155.4 8670159 8671202 R LacI family transcriptional regulator complement(8670159..8671202) Streptomyces avermitilis MA-4680 1217420 NP_828447.1 CDS SAV_7271 NC_003155.4 8671422 8672714 D ABC transporter substrate-binding protein 8671422..8672714 Streptomyces avermitilis MA-4680 1217421 NP_828448.1 CDS SAV_7272 NC_003155.4 8672721 8673614 D ABC transporter permease 8672721..8673614 Streptomyces avermitilis MA-4680 1217422 NP_828449.1 CDS SAV_7273 NC_003155.4 8673611 8674516 D ABC transporter permease 8673611..8674516 Streptomyces avermitilis MA-4680 1217423 NP_828450.1 CDS SAV_7274 NC_003155.4 8674569 8675801 D hypothetical protein 8674569..8675801 Streptomyces avermitilis MA-4680 1217424 NP_828451.1 CDS SAV_7275 NC_003155.4 8675831 8676259 D hypothetical protein 8675831..8676259 Streptomyces avermitilis MA-4680 1217425 NP_828452.1 CDS endoH NC_003155.4 8676290 8677834 D endo-beta-N-acetylglucosaminidase 8676290..8677834 Streptomyces avermitilis MA-4680 1211708 NP_828453.1 CDS ama2 NC_003155.4 8677864 8680878 D alpha-mannosidase 8677864..8680878 Streptomyces avermitilis MA-4680 1211709 NP_828454.1 CDS SAV_7278 NC_003155.4 8680918 8681619 R GntR family transcriptional regulator complement(8680918..8681619) Streptomyces avermitilis MA-4680 1217426 NP_828455.1 CDS SAV_7279 NC_003155.4 8681784 8682830 D sugar ABC transporter substrate-binding protein 8681784..8682830 Streptomyces avermitilis MA-4680 1217427 NP_828456.1 CDS SAV_7280 NC_003155.4 8682827 8684392 D sugar ABC transporter ATP-binding protein 8682827..8684392 Streptomyces avermitilis MA-4680 1217428 NP_828457.1 CDS SAV_7281 NC_003155.4 8684451 8685410 D PF02653: Branched-chain amino acid transport system / permease component; sugar ABC transporter integral membrane subunit 8684451..8685410 Streptomyces avermitilis MA-4680 1217429 NP_828458.1 CDS menC NC_003155.4 8685461 8686801 D mandelate racemase 8685461..8686801 Streptomyces avermitilis MA-4680 1211710 NP_828459.1 CDS SAV_7283 NC_003155.4 8686798 8687553 D PF00106: short chain dehydrogenase; dehydrogenase 8686798..8687553 Streptomyces avermitilis MA-4680 1217430 NP_828460.1 CDS SAV_7284 NC_003155.4 8687550 8688536 D PF00248: Aldo/keto reductase family; oxidoreductase 8687550..8688536 Streptomyces avermitilis MA-4680 1217431 NP_828461.1 CDS SAV_7285 NC_003155.4 8688533 8688847 D PF05336: Protein of unknown function (DUF718); hypothetical protein 8688533..8688847 Streptomyces avermitilis MA-4680 1217432 NP_828462.1 CDS SAV_7286 NC_003155.4 8688832 8689683 D PF04909: Amidohydrolase; hypothetical protein 8688832..8689683 Streptomyces avermitilis MA-4680 1217433 NP_828463.1 CDS SAV_7287 NC_003155.4 8689766 8691193 R PF06762: Protein of unknown function (DUF1222); integral membrane protein complement(8689766..8691193) Streptomyces avermitilis MA-4680 1217434 NP_828464.1 CDS prpM4 NC_003155.4 8691505 8693577 D PF00785: PAC motif; magnesium or manganese-dependent protein phosphatase 8691505..8693577 Streptomyces avermitilis MA-4680 1217435 NP_828465.1 CDS mutM2 NC_003155.4 8693625 8694485 D formamidopyrimidine-DNA glycosylase 8693625..8694485 Streptomyces avermitilis MA-4680 1211711 NP_828466.1 CDS SAV_7290 NC_003155.4 8694529 8695179 R hypothetical protein complement(8694529..8695179) Streptomyces avermitilis MA-4680 1217436 NP_828467.1 CDS SAV_7291 NC_003155.4 8695328 8695843 R hypothetical protein complement(8695328..8695843) Streptomyces avermitilis MA-4680 1217437 NP_828468.1 CDS sig56 NC_003155.4 8695996 8696544 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and or membrane proteins; RNA polymerase sigma factor SigL complement(8695996..8696544) Streptomyces avermitilis MA-4680 1211712 NP_828469.1 CDS SAV_7293 NC_003155.4 8696830 8697978 D lipoprotein 8696830..8697978 Streptomyces avermitilis MA-4680 1217438 NP_828470.1 CDS SAV_7294 NC_003155.4 8697965 8699383 R PF00324: Amino acid permease; amino acid transporter protein complement(8697965..8699383) Streptomyces avermitilis MA-4680 1217439 NP_828471.1 CDS SAV_7295 NC_003155.4 8699546 8700007 R PF00582: Universal stress protein family; hypothetical protein complement(8699546..8700007) Streptomyces avermitilis MA-4680 1217440 NP_828472.1 CDS lysS NC_003155.4 8700179 8703460 D catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 8700179..8703460 Streptomyces avermitilis MA-4680 1211713 NP_828473.1 CDS SAV_7297 NC_003155.4 8703619 8704467 D oligosaccharide deacetylase 8703619..8704467 Streptomyces avermitilis MA-4680 1217441 NP_828474.1 CDS SAV_7298 NC_003155.4 8704497 8705207 R PF04203: Sortase family; hypothetical protein complement(8704497..8705207) Streptomyces avermitilis MA-4680 1217442 NP_828475.1 CDS SAV_7299 NC_003155.4 8705496 8706716 D hypothetical protein 8705496..8706716 Streptomyces avermitilis MA-4680 1217443 NP_828476.1 CDS SAV_7300 NC_003155.4 8706878 8707642 R hypothetical protein complement(8706878..8707642) Streptomyces avermitilis MA-4680 1217444 NP_828477.1 CDS SAV_7301 NC_003155.4 8707659 8708279 R proline-rich protein complement(8707659..8708279) Streptomyces avermitilis MA-4680 1217445 NP_828478.1 CDS SAV_7302 NC_003155.4 8708539 8709492 D PF03640: repeat of unknown function; lipoprotein 8708539..8709492 Streptomyces avermitilis MA-4680 1217446 NP_828479.1 CDS SAV_7303 NC_003155.4 8709840 8710652 D PF04672: Protein of unknown function (DUF574); hypothetical protein 8709840..8710652 Streptomyces avermitilis MA-4680 1217447 NP_828480.1 CDS SAV_7304 NC_003155.4 8710649 8712802 D PF00563: EAL domain, PF00990: GGDEF domain, PF00785: PAC motif; hypothetical protein 8710649..8712802 Streptomyces avermitilis MA-4680 1217448 NP_828481.1 CDS SAV_7305 NC_003155.4 8713321 8714100 D PF00106: short chain dehydrogenase; dehydrogenase 8713321..8714100 Streptomyces avermitilis MA-4680 1217449 NP_828482.1 CDS SAV_7306 NC_003155.4 8714200 8715093 R LysR family transcriptional regulator complement(8714200..8715093) Streptomyces avermitilis MA-4680 1217450 NP_828483.1 CDS qcrB2 NC_003155.4 8715169 8715876 D cytochrome b subunit 8715169..8715876 Streptomyces avermitilis MA-4680 1211714 NP_828484.1 CDS sdhA NC_003155.4 8715880 8717829 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 8715880..8717829 Streptomyces avermitilis MA-4680 1211715 NP_828485.1 CDS sdhB3 NC_003155.4 8717826 8718575 D catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone; succinate dehydrogenase/fumarate reductase iron-sulfur subunit 8717826..8718575 Streptomyces avermitilis MA-4680 1211716 NP_828486.1 CDS SAV_7310 NC_003155.4 8718965 8719735 D hypothetical protein 8718965..8719735 Streptomyces avermitilis MA-4680 1217451 NP_828487.1 CDS plsC7 NC_003155.4 8719984 8720883 D 1-acylglycerol-3-phosphate O-acyltransferase 8719984..8720883 Streptomyces avermitilis MA-4680 1211717 NP_828488.1 CDS SAV_7312 NC_003155.4 8721019 8723946 R hypothetical protein complement(8721019..8723946) Streptomyces avermitilis MA-4680 1217452 NP_828489.1 CDS SAV_7313 NC_003155.4 8724575 8725219 D hypothetical protein 8724575..8725219 Streptomyces avermitilis MA-4680 1217453 NP_828490.1 CDS SAV_7314 NC_003155.4 8725402 8726760 D PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein 8725402..8726760 Streptomyces avermitilis MA-4680 1217454 NP_828491.1 CDS SAV_7315 NC_003155.4 8726798 8727028 R hypothetical protein complement(8726798..8727028) Streptomyces avermitilis MA-4680 1217455 NP_828492.1 CDS SAV_7316 NC_003155.4 8727109 8727753 R methyltransferase complement(8727109..8727753) Streptomyces avermitilis MA-4680 1217456 NP_828493.1 CDS SAV_7317 NC_003155.4 8727769 8728572 D hypothetical protein 8727769..8728572 Streptomyces avermitilis MA-4680 1217457 NP_828494.1 CDS SAV_7318 NC_003155.4 8728594 8729601 R oxygenase complement(8728594..8729601) Streptomyces avermitilis MA-4680 1217458 NP_828495.1 CDS SAV_7319 NC_003155.4 8729675 8730427 R iron-sulfur protein complement(8729675..8730427) Streptomyces avermitilis MA-4680 1217459 NP_828496.1 CDS SAV_7320 NC_003155.4 8730975 8732147 D probably siderophore biosynthesis protein; hypothetical protein 8730975..8732147 Streptomyces avermitilis MA-4680 1217460 NP_828497.1 CDS SAV_7321 NC_003155.4 8732144 8733907 D probably siderophore biosynthesis protein, PF04183: IucA / IucC family; hypothetical protein 8732144..8733907 Streptomyces avermitilis MA-4680 1217461 NP_828498.1 CDS SAV_7322 NC_003155.4 8734011 8735816 D PF04183: IucA / IucC family; iron transport protein 8734011..8735816 Streptomyces avermitilis MA-4680 1217462 NP_828499.1 CDS SAV_7323 NC_003155.4 8735813 8737039 D probably siderophore biosynthesis protein; diaminopimelate decarboxylase 8735813..8737039 Streptomyces avermitilis MA-4680 1217463 NP_828500.1 CDS prpL3 NC_003155.4 8737081 8739531 D PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; magnesium or manganese-dependent protein phosphatase 8737081..8739531 Streptomyces avermitilis MA-4680 1217464 NP_828501.1 CDS SAV_7325 NC_003155.4 8739584 8740081 R PF03992: Antibiotic biosynthesis monooxygenase; hypothetical protein complement(8739584..8740081) Streptomyces avermitilis MA-4680 1217465 NP_828502.1 CDS SAV_7326 NC_003155.4 8740090 8740746 D transcriptional regulator 8740090..8740746 Streptomyces avermitilis MA-4680 1217466 NP_828503.1 CDS SAV_7327 NC_003155.4 8740960 8741457 D hypothetical protein 8740960..8741457 Streptomyces avermitilis MA-4680 1217467 NP_828504.1 CDS SAV_7328 NC_003155.4 8741489 8741746 R PF07311: Protein of unknown function (DUF1458); hypothetical protein complement(8741489..8741746) Streptomyces avermitilis MA-4680 1217468 NP_828505.1 CDS SAV_7329 NC_003155.4 8741916 8743166 D sugar transporter sugar binding protein 8741916..8743166 Streptomyces avermitilis MA-4680 1217469 NP_828506.1 CDS prpM5 NC_003155.4 8743193 8745301 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(8743193..8745301) Streptomyces avermitilis MA-4680 1217470 NP_828507.1 CDS SAV_7331 NC_003155.4 8745511 8748213 D LuxR family transcriptional regulator 8745511..8748213 Streptomyces avermitilis MA-4680 1217471 NP_828508.1 CDS SAV_7332 NC_003155.4 8748224 8750050 D PF07690: Major Facilitator Superfamily; transmembrane transport protein 8748224..8750050 Streptomyces avermitilis MA-4680 1217472 NP_828509.1 CDS SAV_7333 NC_003155.4 8750152 8750583 D integral membrane protein 8750152..8750583 Streptomyces avermitilis MA-4680 1217473 NP_828510.1 CDS SAV_7334 NC_003155.4 8750726 8750923 D hypothetical protein 8750726..8750923 Streptomyces avermitilis MA-4680 1217474 NP_828511.1 CDS SAV_7335 NC_003155.4 8751157 8751822 D PF03729: Short repeat of unknown function (DUF308); integral membrane protein 8751157..8751822 Streptomyces avermitilis MA-4680 1217475 NP_828512.1 CDS SAV_7336 NC_003155.4 8751955 8752452 D integral membrane protein 8751955..8752452 Streptomyces avermitilis MA-4680 1217476 NP_828513.1 CDS SAV_7337 NC_003155.4 8752486 8752932 D integral membrane protein 8752486..8752932 Streptomyces avermitilis MA-4680 1217477 NP_828514.1 CDS SAV_7338 NC_003155.4 8753067 8754068 R hypothetical protein complement(8753067..8754068) Streptomyces avermitilis MA-4680 1217478 NP_828515.1 CDS SAV_7339 NC_003155.4 8754065 8754892 R PF02553: Cobalt transport protein component CbiN; hypothetical protein complement(8754065..8754892) Streptomyces avermitilis MA-4680 1217479 NP_828516.1 CDS SAV_7340 NC_003155.4 8754892 8756214 R PF03781: Domain of unknown function (DUF323); hypothetical protein complement(8754892..8756214) Streptomyces avermitilis MA-4680 1217480 NP_828517.1 CDS gshA NC_003155.4 8756211 8757485 R glutamate-cysteine ligase complement(8756211..8757485) Streptomyces avermitilis MA-4680 1217481 NP_828518.1 CDS SAV_7342 NC_003155.4 8757636 8758619 D hypothetical protein 8757636..8758619 Streptomyces avermitilis MA-4680 1217482 NP_828519.1 CDS SAV_7343 NC_003155.4 8758604 8759059 R hypothetical protein complement(8758604..8759059) Streptomyces avermitilis MA-4680 1217483 NP_828520.1 CDS SAV_7344 NC_003155.4 8759149 8760630 R PF01145: SPFH domain / Band 7 family; hypothetical protein complement(8759149..8760630) Streptomyces avermitilis MA-4680 1217484 NP_828521.1 CDS amiE2 NC_003155.4 8760992 8762506 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(8760992..8762506) Streptomyces avermitilis MA-4680 1217485 NP_828522.1 CDS SAV_7346 NC_003155.4 8762699 8763733 D LacI family transcriptional regulator 8762699..8763733 Streptomyces avermitilis MA-4680 1217486 NP_828523.1 CDS trxA3 NC_003155.4 8763919 8764308 R PF00085: Thioredoxin; thioredoxin complement(8763919..8764308) Streptomyces avermitilis MA-4680 1211718 NP_828524.1 CDS lpdB2 NC_003155.4 8764437 8765870 D similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase; oxidoreductase 8764437..8765870 Streptomyces avermitilis MA-4680 1217487 NP_828525.1 CDS def NC_003155.4 8766187 8766861 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(8766187..8766861) Streptomyces avermitilis MA-4680 1211719 NP_828526.1 CDS SAV_7350 NC_003155.4 8767057 8768469 D PF03929: Uncharacterized iron-regulated membrane protein (DUF337); integral membrane protein 8767057..8768469 Streptomyces avermitilis MA-4680 1217488 NP_828527.1 CDS SAV_7351 NC_003155.4 8768501 8768914 D hypothetical protein 8768501..8768914 Streptomyces avermitilis MA-4680 1217489 NP_828528.1 CDS SAV_7352 NC_003155.4 8769198 8769545 R hypothetical protein complement(8769198..8769545) Streptomyces avermitilis MA-4680 1217490 NP_828529.1 CDS SAV_7353 NC_003155.4 8769623 8770087 R hypothetical protein complement(8769623..8770087) Streptomyces avermitilis MA-4680 1217491 NP_828530.1 CDS SAV_7354 NC_003155.4 8770084 8770611 R similar to dihydrolipoamide dehydrogenase, PF00070: Pyridine nucleotide-disulphide oxidoreductase; MarR family transcriptional regulator complement(8770084..8770611) Streptomyces avermitilis MA-4680 1217492 NP_828531.1 CDS SAV_7355 NC_003155.4 8770756 8771721 D PF02678: Pirin; pirin-like protein 8770756..8771721 Streptomyces avermitilis MA-4680 1217493 NP_828532.1 CDS SAV_7356 NC_003155.4 8772756 8773655 R truncated; monophenol monooxygenase complement(8772756..8773655) Streptomyces avermitilis MA-4680 1217494 NP_828533.1 CDS SAV_7357 NC_003155.4 8774009 8775772 R ABC transporter ATP-binding protein complement(8774009..8775772) Streptomyces avermitilis MA-4680 1217495 NP_828534.1 CDS SAV_7358 NC_003155.4 8775769 8776962 R PF04101: Glycosyltransferase family 28 C-terminal domain; glycosyl transferase complement(8775769..8776962) Streptomyces avermitilis MA-4680 1217496 NP_828535.1 CDS SAV_7359 NC_003155.4 8776963 8777766 R pks1 gene cluster, PF00561: alpha/beta hydrolase fold; hydrolase complement(8776963..8777766) Streptomyces avermitilis MA-4680 1217497 NP_828536.1 CDS pks1-1 NC_003155.4 8777769 8778044 R pks1 gene cluster; ACP complement(8777769..8778044) Streptomyces avermitilis MA-4680 1217498 NP_828537.1 CDS pks1-2 NC_003155.4 8778095 8782666 R pks1 gene cluster; modular polyketide synthase complement(8778095..8782666) Streptomyces avermitilis MA-4680 1217499 NP_828538.1 CDS pks1-3 NC_003155.4 8782669 8789766 R pks1 gene cluster; modular polyketide synthase complement(8782669..8789766) Streptomyces avermitilis MA-4680 1217500 NP_828539.1 CDS pnbA NC_003155.4 8790510 8791988 R para-nitrobenzyl esterase complement(8790510..8791988) Streptomyces avermitilis MA-4680 1211720 NP_828540.1 CDS SAV_7364 NC_003155.4 8792326 8792940 R hypothetical protein complement(8792326..8792940) Streptomyces avermitilis MA-4680 1217501 NP_828541.1 CDS hypX NC_003155.4 8793210 8795051 D similar to HoxX protein; [NiFe] hydrogenase maturation 8793210..8795051 Streptomyces avermitilis MA-4680 1217502 NP_828542.1 CDS hydA NC_003155.4 8795100 8796188 D PF01058: NADH ubiquinone oxidoreductase, 20 Kd subunit; cytochrome C3-like [NiFe] hydrogenase small subunit 8795100..8796188 Streptomyces avermitilis MA-4680 1211721 NP_828543.1 CDS hydB NC_003155.4 8796269 8798053 D PF00374: Nickel-dependent hydrogenase; cytochrome C3-like [NiFe] hydrogenase large subunit 8796269..8798053 Streptomyces avermitilis MA-4680 1211722 NP_828544.1 CDS SAV_7368 NC_003155.4 8798050 8798640 D similar to Ralstonia eutropha gi:38637731; hypothetical protein 8798050..8798640 Streptomyces avermitilis MA-4680 1217503 NP_828545.1 CDS SAV_7369 NC_003155.4 8798637 8799305 D similar to Ralstonia eutropha gi:38637732; hypothetical protein 8798637..8799305 Streptomyces avermitilis MA-4680 1217504 NP_828546.1 CDS SAV_7370 NC_003155.4 8799302 8799994 D similar to Ralstonia eutropha gi:38637733; hypothetical protein 8799302..8799994 Streptomyces avermitilis MA-4680 1217505 NP_828547.1 CDS SAV_7371 NC_003155.4 8799991 8801427 D similar to Ralstonia eutropha gi:38637734; hypothetical protein 8799991..8801427 Streptomyces avermitilis MA-4680 1217506 NP_828548.1 CDS hupD NC_003155.4 8801424 8801975 D similar to Ralstonia eutropha gi:38637735, PF01750: Hydrogenase maturation protease; [NiFe] hydrogenase-specific C-terminal protease 8801424..8801975 Streptomyces avermitilis MA-4680 1217507 NP_828549.1 CDS hypA NC_003155.4 8802301 8802696 D PF01155: Hydrogenase expression/synthesis hypA family; [NiFe] hydrogenase expression/formation protein 8802301..8802696 Streptomyces avermitilis MA-4680 1211723 NP_828550.1 CDS hypB NC_003155.4 8802700 8803527 D PF02492: CobW/HypB/UreG, nucleotide-binding domain; [NiFe] hydrogenase expression/formation protein 8802700..8803527 Streptomyces avermitilis MA-4680 1211724 NP_828551.1 CDS hypF NC_003155.4 8803563 8805929 D PF01300: yrdC domain; [NiFe] hydrogenase maturation protein 8803563..8805929 Streptomyces avermitilis MA-4680 1211725 NP_828552.1 CDS hypC NC_003155.4 8805990 8806310 D PF01455: HupF/HypC family; [NiFe] hydrogenase expression/formation protein 8805990..8806310 Streptomyces avermitilis MA-4680 1211726 NP_828553.1 CDS hypD NC_003155.4 8806307 8807431 D PF01924: Hydrogenase formation hypA family; [NiFe] hydrogenase expression/formation protein 8806307..8807431 Streptomyces avermitilis MA-4680 1211727 NP_828554.1 CDS hypE NC_003155.4 8807424 8808500 D PF02769: AIR synthase related protein, C-terminal domain; [NiFe] hydrogenase expression/formation protein 8807424..8808500 Streptomyces avermitilis MA-4680 1211728 NP_828555.1 CDS SAV_7379 NC_003155.4 8808563 8808949 R hypothetical protein complement(8808563..8808949) Streptomyces avermitilis MA-4680 1217508 NP_828556.1 CDS SAV_7380 NC_003155.4 8809365 8809685 R hypothetical protein complement(8809365..8809685) Streptomyces avermitilis MA-4680 1217509 NP_828557.1 CDS SAV_7381 NC_003155.4 8809992 8810519 D hypothetical protein 8809992..8810519 Streptomyces avermitilis MA-4680 1217510 NP_828558.1 CDS SAV_7382 NC_003155.4 8810525 8811163 D PF01799: [2Fe-2S] binding domain; oxidoreductase iron-sulphur binding subunit 8810525..8811163 Streptomyces avermitilis MA-4680 1217511 NP_828559.1 CDS SAV_7383 NC_003155.4 8811160 8812152 D PF00941: FAD binding domain in molybdopterin dehydrogenase; oxidoreductase molybdopterin binding subunit 8811160..8812152 Streptomyces avermitilis MA-4680 1217512 NP_828560.1 CDS SAV_7384 NC_003155.4 8812222 8814342 D PF02738: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; oxidoreductase 8812222..8814342 Streptomyces avermitilis MA-4680 1217513 NP_828561.1 CDS SAV_7385 NC_003155.4 8814519 8814695 D hypothetical protein 8814519..8814695 Streptomyces avermitilis MA-4680 1217514 NP_828562.1 CDS SAV_7386 NC_003155.4 8814779 8815009 R hypothetical protein complement(8814779..8815009) Streptomyces avermitilis MA-4680 1217515 NP_828563.1 CDS terD5 NC_003155.4 8815160 8815735 D PF02342: Bacterial stress protein; tellurium resistance protein 8815160..8815735 Streptomyces avermitilis MA-4680 1217516 NP_828564.1 CDS SAV_7388 NC_003155.4 8815808 8816485 D hypothetical protein 8815808..8816485 Streptomyces avermitilis MA-4680 1217517 NP_828565.1 CDS SAV_7389 NC_003155.4 8816539 8817780 R PF00999: Sodium/hydrogen exchanger family; sodium/proton antiporter complement(8816539..8817780) Streptomyces avermitilis MA-4680 1217518 NP_828566.1 CDS SAV_7390 NC_003155.4 8817785 8818210 R PF02080: TrkA-C domain; hypothetical protein complement(8817785..8818210) Streptomyces avermitilis MA-4680 1217519 NP_828567.1 CDS SAV_7391 NC_003155.4 8818383 8819549 D two-component system sensor kinase 8818383..8819549 Streptomyces avermitilis MA-4680 1217520 NP_828568.1 CDS SAV_7392 NC_003155.4 8819549 8820220 D two-component system response regulator 8819549..8820220 Streptomyces avermitilis MA-4680 1217521 NP_828569.1 CDS SAV_7393 NC_003155.4 8820563 8821054 R regulatory protein complement(8820563..8821054) Streptomyces avermitilis MA-4680 1217522 NP_828570.1 CDS SAV_7394 NC_003155.4 8821348 8821674 D hypothetical protein 8821348..8821674 Streptomyces avermitilis MA-4680 1217523 NP_828571.1 CDS amyA5 NC_003155.4 8821773 8823770 D alpha-amylase 8821773..8823770 Streptomyces avermitilis MA-4680 1211729 NP_828572.1 CDS treS2 NC_003155.4 8823767 8825518 D alpha-amylase family; trehalose synthase 8823767..8825518 Streptomyces avermitilis MA-4680 1211730 NP_828573.1 CDS SAV_7397 NC_003155.4 8825547 8826941 D pep2 protein 8825547..8826941 Streptomyces avermitilis MA-4680 1217524 NP_828574.1 CDS SAV_7398 NC_003155.4 8826938 8827363 D frameshift; glycogen branching enzyme 8826938..8827363 Streptomyces avermitilis MA-4680 1217525 NP_828575.1 CDS SAV_7399 NC_003155.4 8827360 8829138 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 8827360..8829138 Streptomyces avermitilis MA-4680 1217526 NP_828576.1 CDS sig57 NC_003155.4 8829444 8830238 D RNA polymerase alternative sigma factor; RNA polymerase sigma factor 8829444..8830238 Streptomyces avermitilis MA-4680 1211731 NP_828577.1 CDS SAV_7401 NC_003155.4 8830427 8830816 R PF03861: ANTAR domain; hypothetical protein complement(8830427..8830816) Streptomyces avermitilis MA-4680 1217527 NP_828578.1 CDS SAV_7402 NC_003155.4 8830948 8831559 D PF03364: Streptomyces cyclase/dehydrase; cyclase/dehydrase 8830948..8831559 Streptomyces avermitilis MA-4680 1217528 NP_828579.1 CDS SAV_7403 NC_003155.4 8831556 8832605 D PF00296: Luciferase-like monooxygenase; FMN-dependent monooxygenase 8831556..8832605 Streptomyces avermitilis MA-4680 1217529 NP_828580.1 CDS SAV_7404 NC_003155.4 8832701 8834011 R PF02687: Predicted permease; transmembrane transport protein complement(8832701..8834011) Streptomyces avermitilis MA-4680 1217530 NP_828581.1 CDS SAV_7405 NC_003155.4 8834015 8834800 R ABC transporter ATP-binding protein complement(8834015..8834800) Streptomyces avermitilis MA-4680 1217531 NP_828582.1 CDS SAV_7406 NC_003155.4 8834887 8835639 D ABC transporter permease 8834887..8835639 Streptomyces avermitilis MA-4680 1217532 NP_828583.1 CDS SAV_7407 NC_003155.4 8835636 8836307 D ABC transporter permease 8835636..8836307 Streptomyces avermitilis MA-4680 1217533 NP_828584.1 CDS SAV_7408 NC_003155.4 8836304 8837239 D amino acid ABC transporter amino acid-binding protein 8836304..8837239 Streptomyces avermitilis MA-4680 1217534 NP_828585.1 CDS SAV_7409 NC_003155.4 8837282 8838436 R ABC transporter ATP-binding protein complement(8837282..8838436) Streptomyces avermitilis MA-4680 1217535 NP_828586.1 CDS SAV_7410 NC_003155.4 8838469 8839164 R PF02589: Uncharacterized ACR, YkgG family COG1556; hypothetical protein complement(8838469..8839164) Streptomyces avermitilis MA-4680 1217536 NP_828587.1 CDS SAV_7411 NC_003155.4 8839128 8840603 R iron-sulfur protein complement(8839128..8840603) Streptomyces avermitilis MA-4680 1217537 NP_828588.1 CDS SAV_7412 NC_003155.4 8840600 8841355 R fumarate reductase-related protein complement(8840600..8841355) Streptomyces avermitilis MA-4680 1217538 NP_828589.1 CDS rhaB NC_003155.4 8841426 8842871 R rhamnulokinase complement(8841426..8842871) Streptomyces avermitilis MA-4680 1217539 NP_828590.1 CDS srlD NC_003155.4 8842868 8844907 R short chain dehydrogenase complement(8842868..8844907) Streptomyces avermitilis MA-4680 1211732 NP_828591.1 CDS SAV_7415 NC_003155.4 8845064 8846224 R sugar isomerase complement(8845064..8846224) Streptomyces avermitilis MA-4680 1217540 NP_828592.1 CDS SAV_7416 NC_003155.4 8846486 8848003 D ABC transporter ATP-binding protein 8846486..8848003 Streptomyces avermitilis MA-4680 1217541 NP_828593.1 CDS SAV_7417 NC_003155.4 8848059 8849099 D ABC transporter permease 8848059..8849099 Streptomyces avermitilis MA-4680 1217542 NP_828594.1 CDS SAV_7418 NC_003155.4 8849092 8850090 D ABC transporter permease 8849092..8850090 Streptomyces avermitilis MA-4680 1217543 NP_828595.1 CDS SAV_7419 NC_003155.4 8850119 8851201 D solute-binding lipoprotein 8850119..8851201 Streptomyces avermitilis MA-4680 1217544 NP_828596.1 CDS SAV_7420 NC_003155.4 8851228 8851539 D PF05336: Protein of unknown function (DUF718); hypothetical protein 8851228..8851539 Streptomyces avermitilis MA-4680 1217545 NP_828597.1 CDS SAV_7421 NC_003155.4 8851550 8852962 D hypothetical protein 8851550..8852962 Streptomyces avermitilis MA-4680 1217546 NP_828598.1 CDS SAV_7422 NC_003155.4 8853042 8854067 D LacI family transcriptional regulator 8853042..8854067 Streptomyces avermitilis MA-4680 1217547 NP_828599.1 CDS SAV_7423 NC_003155.4 8854146 8855498 D PF00561: alpha/beta hydrolase fold; prolyl aminopeptidase 8854146..8855498 Streptomyces avermitilis MA-4680 1217548 NP_828600.1 CDS sig58 NC_003155.4 8855573 8856541 D ECF subfamily RNA polymerase sigma factor 8855573..8856541 Streptomyces avermitilis MA-4680 1211733 NP_828601.1 CDS SAV_7425 NC_003155.4 8856821 8857651 D PF00805: Pentapeptide repeats (8 copies); hypothetical protein 8856821..8857651 Streptomyces avermitilis MA-4680 1217549 NP_828602.1 CDS cyp27 NC_003155.4 8857613 8859127 R CYP102B2; cytochrome P450 complement(8857613..8859127) Streptomyces avermitilis MA-4680 1211734 NP_828603.1 CDS SAV_7427 NC_003155.4 8859236 8859844 D TetR family transcriptional regulator 8859236..8859844 Streptomyces avermitilis MA-4680 1217550 NP_828604.1 CDS SAV_7428 NC_003155.4 8859930 8860658 D hypothetical protein 8859930..8860658 Streptomyces avermitilis MA-4680 1217551 NP_828605.1 CDS SAV_7429 NC_003155.4 8860626 8861852 R hypothetical protein complement(8860626..8861852) Streptomyces avermitilis MA-4680 1217552 NP_828606.1 CDS SAV_7430 NC_003155.4 8861978 8863036 R integral membrane protein complement(8861978..8863036) Streptomyces avermitilis MA-4680 1217553 NP_828607.1 CDS SAV_7431 NC_003155.4 8863085 8864338 R PF06081: Bacterial protein of unknown function (DUF939); integral membrane protein complement(8863085..8864338) Streptomyces avermitilis MA-4680 1217554 NP_828608.1 CDS SAV_7432 NC_003155.4 8864603 8865010 R hypothetical protein complement(8864603..8865010) Streptomyces avermitilis MA-4680 1217555 NP_828609.1 CDS SAV_7433 NC_003155.4 8865143 8866588 D PF05139: Erythromycin esterase; hypothetical protein 8865143..8866588 Streptomyces avermitilis MA-4680 1217556 NP_828610.1 CDS SAV_7434 NC_003155.4 8866617 8867105 R hypothetical protein complement(8866617..8867105) Streptomyces avermitilis MA-4680 1217557 NP_828611.1 CDS SAV_7435 NC_003155.4 8867219 8867482 R hypothetical protein complement(8867219..8867482) Streptomyces avermitilis MA-4680 1217558 NP_828612.1 CDS SAV_7436 NC_003155.4 8867539 8868828 D transcriptional regulator 8867539..8868828 Streptomyces avermitilis MA-4680 1217559 NP_828613.1 CDS SAV_7437 NC_003155.4 8868940 8869275 D hypothetical protein 8868940..8869275 Streptomyces avermitilis MA-4680 1217560 NP_828614.1 CDS SAV_7438 NC_003155.4 8869571 8870539 R PF00106: short chain dehydrogenase; oxidoreductase complement(8869571..8870539) Streptomyces avermitilis MA-4680 1217561 NP_828615.1 CDS SAV_7439 NC_003155.4 8870855 8871520 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(8870855..8871520) Streptomyces avermitilis MA-4680 1217562 NP_828616.1 CDS SAV_7440 NC_003155.4 8871561 8872604 R PF02231: PHP domain N-terminal region; hypothetical protein complement(8871561..8872604) Streptomyces avermitilis MA-4680 1217563 NP_828617.1 CDS SAV_7441 NC_003155.4 8872829 8873065 D hypothetical protein 8872829..8873065 Streptomyces avermitilis MA-4680 1217564 NP_828618.1 CDS lamA2 NC_003155.4 8873224 8874486 R endo-1,3-beta-glucanase complement(8873224..8874486) Streptomyces avermitilis MA-4680 1217565 NP_828619.1 CDS SAV_7443 NC_003155.4 8874615 8875205 R PF04892: VanZ like family; integral membrane protein complement(8874615..8875205) Streptomyces avermitilis MA-4680 1217566 NP_828620.1 CDS SAV_7444 NC_003155.4 8875490 8876074 D PF04066: Multiple resistance and pH regulation protein F (MrpF / PhaF); hypothetical protein 8875490..8876074 Streptomyces avermitilis MA-4680 1217567 NP_828621.1 CDS SAV_7445 NC_003155.4 8876067 8876342 D hypothetical protein 8876067..8876342 Streptomyces avermitilis MA-4680 1217568 NP_828622.1 CDS SAV_7446 NC_003155.4 8876339 8877079 D PF04039: Domain related to MnhB subunit of Na+/H+ antiporter; hypothetical protein 8876339..8877079 Streptomyces avermitilis MA-4680 1217569 NP_828623.1 CDS SAV_7447 NC_003155.4 8877195 8877545 D PF00420: NADH-ubiquinone/plastoquinone oxidore; dehydrogenase 8877195..8877545 Streptomyces avermitilis MA-4680 1217570 NP_828624.1 CDS mrpD NC_003155.4 8877545 8879302 D PF00361: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-dehydrogenase 8877545..8879302 Streptomyces avermitilis MA-4680 1217571 NP_828625.1 CDS SAV_7449 NC_003155.4 8879321 8880004 R protein complement(8879321..8880004) Streptomyces avermitilis MA-4680 1217572 NP_828626.1 CDS SAV_7450 NC_003155.4 8880199 8880600 R PF00009: Elongation factor Tu GTP binding domain; hypothetical protein complement(8880199..8880600) Streptomyces avermitilis MA-4680 1217573 NP_828627.1 CDS prsA2 NC_003155.4 8880691 8881644 D ribose-phosphate pyrophosphokinase 8880691..8881644 Streptomyces avermitilis MA-4680 1211735 NP_828628.1 CDS SAV_7452 NC_003155.4 8881791 8882198 R PF01740: STAS domain; anti-sigma factor antagonist complement(8881791..8882198) Streptomyces avermitilis MA-4680 1217574 NP_828629.1 CDS SAV_7453 NC_003155.4 8882837 8883784 R PF00107: Zinc-binding dehydrogenase; dehydrogenase complement(8882837..8883784) Streptomyces avermitilis MA-4680 1217575 NP_828630.1 CDS SAV_7454 NC_003155.4 8883856 8884803 D AraC family transcription regulator 8883856..8884803 Streptomyces avermitilis MA-4680 1217576 NP_828631.1 CDS SAV_7455 NC_003155.4 8884951 8885655 R esterase complement(8884951..8885655) Streptomyces avermitilis MA-4680 1217577 NP_828632.1 CDS SAV_7456 NC_003155.4 8885753 8886658 D hypothetical protein 8885753..8886658 Streptomyces avermitilis MA-4680 1217578 NP_828633.1 CDS SAV_7457 NC_003155.4 8886674 8887237 R TetR family transcriptional regulator complement(8886674..8887237) Streptomyces avermitilis MA-4680 1217579 NP_828634.1 CDS SAV_7458 NC_003155.4 8887243 8887605 R PF06993: Protein of unknown function (DUF1304); hypothetical protein complement(8887243..8887605) Streptomyces avermitilis MA-4680 1217580 NP_828635.1 CDS SAV_7459 NC_003155.4 8887817 8889352 D membrane-associated oxidoreductase 8887817..8889352 Streptomyces avermitilis MA-4680 1217581 NP_828636.1 CDS SAV_7460 NC_003155.4 8889484 8889948 D PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein 8889484..8889948 Streptomyces avermitilis MA-4680 1217582 NP_828637.1 CDS SAV_7461 NC_003155.4 8890031 8890423 D PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 8890031..8890423 Streptomyces avermitilis MA-4680 1217583 NP_828638.1 CDS SAV_7462 NC_003155.4 8890451 8890759 R hypothetical protein complement(8890451..8890759) Streptomyces avermitilis MA-4680 1217584 NP_828639.1 CDS SAV_7463 NC_003155.4 8890796 8891812 R PF00043: Glutathione S-transferase, C-terminal domain; glutathione S-transferase complement(8890796..8891812) Streptomyces avermitilis MA-4680 1217585 NP_828640.1 CDS SAV_7464 NC_003155.4 8891921 8892991 D PF01545: Cation efflux family; transport protein 8891921..8892991 Streptomyces avermitilis MA-4680 1217586 NP_828641.1 CDS SAV_7465 NC_003155.4 8893156 8893599 R PF04075: Domain of unknown function (DUF385); hypothetical protein complement(8893156..8893599) Streptomyces avermitilis MA-4680 1217587 NP_828642.1 CDS SAV_7466 NC_003155.4 8893764 8894396 R PF01810: LysE type translocator; hypothetical protein complement(8893764..8894396) Streptomyces avermitilis MA-4680 1217588 NP_828643.1 CDS SAV_7467 NC_003155.4 8894606 8895115 R PF00657: GDSL-like Lipase/Acylhydrolase; hypothetical protein complement(8894606..8895115) Streptomyces avermitilis MA-4680 1217589 NP_828644.1 CDS SAV_7468 NC_003155.4 8895148 8895834 D hypothetical protein 8895148..8895834 Streptomyces avermitilis MA-4680 1217590 NP_828645.1 CDS cyp28 NC_003155.4 8895853 8897103 D CYP105D7, fdxH is located at downstream; cytochrome P450 hydroxylase 8895853..8897103 Streptomyces avermitilis MA-4680 1211736 NP_828646.1 CDS fdxH NC_003155.4 8897117 8897401 D ferredoxin 8897117..8897401 Streptomyces avermitilis MA-4680 1211737 NP_828647.1 CDS SAV_7471 NC_003155.4 8897749 8898303 R TetR family transcriptional regulator complement(8897749..8898303) Streptomyces avermitilis MA-4680 1217591 NP_828648.1 CDS SAV_7472 NC_003155.4 8898430 8898891 D PF07080: Protein of unknown function (DUF1348); hypothetical protein 8898430..8898891 Streptomyces avermitilis MA-4680 1217592 NP_828649.1 CDS SAV_7473 NC_003155.4 8898901 8899431 D possible flavoprotein involved in panthothenate metabolism; hypothetical protein 8898901..8899431 Streptomyces avermitilis MA-4680 1217593 NP_828650.1 CDS SAV_7474 NC_003155.4 8899700 8900506 R hypothetical protein complement(8899700..8900506) Streptomyces avermitilis MA-4680 1217594 NP_828651.1 CDS SAV_7475 NC_003155.4 8900898 8901785 D PF00561: alpha/beta hydrolase fold; hydrolase 8900898..8901785 Streptomyces avermitilis MA-4680 1217595 NP_828652.1 CDS SAV_7476 NC_003155.4 8902269 8905136 D PF00652: QXW lectin repeat; hydrolase 8902269..8905136 Streptomyces avermitilis MA-4680 1217596 NP_828653.1 CDS arsB NC_003155.4 8905145 8906488 R PF02040: Arsenical pump membrane protein; membrane efflux protein complement(8905145..8906488) Streptomyces avermitilis MA-4680 1217597 NP_828654.1 CDS prpL4 NC_003155.4 8906510 8908948 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(8906510..8908948) Streptomyces avermitilis MA-4680 1217598 NP_828655.1 CDS bga8 NC_003155.4 8909193 8912285 D beta-galactosidase precursor 8909193..8912285 Streptomyces avermitilis MA-4680 1211738 NP_828656.1 CDS SAV_7480 NC_003155.4 8913182 8915059 D PF00652: QXW lectin repeat; hydrolase 8913182..8915059 Streptomyces avermitilis MA-4680 1217599 NP_828657.1 CDS SAV_7481 NC_003155.4 8915149 8916126 R PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; phosphoglycerate dehydrogenase complement(8915149..8916126) Streptomyces avermitilis MA-4680 1217600 NP_828658.1 CDS lldA NC_003155.4 8916123 8917292 R PF01070: FMN-dependent dehydrogenase; L-lactate 2-monooxygenase complement(8916123..8917292) Streptomyces avermitilis MA-4680 1211739 NP_828659.1 CDS SAV_7483 NC_003155.4 8917603 8918064 R PF01243: Pyridoxamine 5'-phosphate oxidase; hypothetical protein complement(8917603..8918064) Streptomyces avermitilis MA-4680 1217601 NP_828660.1 CDS SAV_7484 NC_003155.4 8918174 8919001 R N5,N10- methylenetetrahydromethanopterin reductase-related protein complement(8918174..8919001) Streptomyces avermitilis MA-4680 1217602 NP_828661.1 CDS SAV_7485 NC_003155.4 8919152 8919628 R hypothetical protein complement(8919152..8919628) Streptomyces avermitilis MA-4680 1217603 NP_828662.1 CDS sti2 NC_003155.4 8920060 8920494 D subtilase-type; inhibits bacterial serine proteases; protease inhibitor protein 8920060..8920494 Streptomyces avermitilis MA-4680 1211740 NP_828663.1 CDS SAV_7487 NC_003155.4 8920630 8920860 R hypothetical protein complement(8920630..8920860) Streptomyces avermitilis MA-4680 1217604 NP_828664.1 CDS SAV_7488 NC_003155.4 8921026 8921610 D PF00583: Acetyltransferase (GNAT) family; hypothetical protein 8921026..8921610 Streptomyces avermitilis MA-4680 1217605 NP_828665.1 CDS SAV_7489 NC_003155.4 8921717 8923294 D PF01569: PAP2 superfamily; hypothetical protein 8921717..8923294 Streptomyces avermitilis MA-4680 1217606 NP_828666.1 CDS SAV_7490 NC_003155.4 8923302 8924804 R PF07690: Major Facilitator Superfamily; transmembrane efflux protein complement(8923302..8924804) Streptomyces avermitilis MA-4680 1217607 NP_828667.1 CDS SAV_7491 NC_003155.4 8924911 8925477 D PF05146: Aha1 domain; hypothetical protein 8924911..8925477 Streptomyces avermitilis MA-4680 1217608 NP_828668.1 CDS SAV_7492 NC_003155.4 8925482 8928298 R ABC transporter ATP-binding protein complement(8925482..8928298) Streptomyces avermitilis MA-4680 1217609 NP_828669.1 CDS SAV_7493 NC_003155.4 8928300 8930549 R ABC transporter ATP-binding protein complement(8928300..8930549) Streptomyces avermitilis MA-4680 1217610 NP_828670.1 CDS SAV_7494 NC_003155.4 8930534 8931340 R PF00364: Biotin-requiring enzyme; hypothetical protein complement(8930534..8931340) Streptomyces avermitilis MA-4680 1217611 NP_828671.1 CDS SAV_7495 NC_003155.4 8931460 8931675 R hypothetical protein complement(8931460..8931675) Streptomyces avermitilis MA-4680 1217612 NP_828672.1 CDS SAV_7496 NC_003155.4 8932137 8932577 R PF03061: Thioesterase superfamily; hypothetical protein complement(8932137..8932577) Streptomyces avermitilis MA-4680 1217613 NP_828673.1 CDS SAV_7497 NC_003155.4 8932746 8934104 D PF02983: Alpha-lytic protease prodomain; protease precursor 8932746..8934104 Streptomyces avermitilis MA-4680 1217614 NP_828674.1 CDS prpJ8 NC_003155.4 8934191 8936329 R PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase complement(8934191..8936329) Streptomyces avermitilis MA-4680 1217615 NP_828675.1 CDS amfR NC_003155.4 8936797 8937468 D AmfR homolog protein; two-component system response regulator 8936797..8937468 Streptomyces avermitilis MA-4680 1211741 NP_828676.1 CDS amfA NC_003155.4 8937310 8939205 R AmfA/RamB homolog protein; ABC transporter ATP-binding protein complement(8937310..8939205) Streptomyces avermitilis MA-4680 1211742 NP_828677.1 CDS amfB NC_003155.4 8939202 8940989 R AmfB/RamA homolog protein; ABC transporter ATP-binding protein complement(8939202..8940989) Streptomyces avermitilis MA-4680 1211743 NP_828678.1 CDS amfS NC_003155.4 8941080 8941196 R AmfS/RamS homolog protein; AmfS protein complement(8941080..8941196) Streptomyces avermitilis MA-4680 1211744 NP_828679.1 CDS amfT NC_003155.4 8941260 8943908 R AmfT homolog protein; membrane translocator complement(8941260..8943908) Streptomyces avermitilis MA-4680 1211745 NP_828680.1 CDS prpC7 NC_003155.4 8944160 8946703 D PF01590: GAF domain; magnesium or manganese-dependent protein phosphatase 8944160..8946703 Streptomyces avermitilis MA-4680 1217616 NP_828681.1 CDS SAV_7505 NC_003155.4 8946807 8947310 D PF00149: Calcineurin-like phosphoesterase; hypothetical protein 8946807..8947310 Streptomyces avermitilis MA-4680 1217617 NP_828682.1 CDS pucA NC_003155.4 8947356 8948462 R xanthine dehydrogenase complement(8947356..8948462) Streptomyces avermitilis MA-4680 1211746 NP_828683.1 CDS tetM NC_003155.4 8948716 8950707 D PF00009: Elongation factor Tu GTP binding domain; tetracycline resistance protein 8948716..8950707 Streptomyces avermitilis MA-4680 1211747 NP_828684.1 CDS SAV_7508 NC_003155.4 8950741 8952684 D PF00150: Cellulase (glycosyl hydrolase family 5); endoglycosylceramidase 8950741..8952684 Streptomyces avermitilis MA-4680 1217618 NP_828685.1 CDS pkn32 NC_003155.4 8952722 8953972 R serine/threonine protein kinase complement(8952722..8953972) Streptomyces avermitilis MA-4680 1211748 NP_828686.1 CDS SAV_7510 NC_003155.4 8954182 8954841 D TetR family transcriptional regulator 8954182..8954841 Streptomyces avermitilis MA-4680 1217619 NP_828687.1 CDS SAV_7511 NC_003155.4 8954887 8955165 R IS630 family; IS630 family transposase complement(8954887..8955165) Streptomyces avermitilis MA-4680 1217620 NP_828688.1 CDS SAV_7512 NC_003155.4 8955207 8956307 R IS110 family; IS110 family transposase complement(8955207..8956307) Streptomyces avermitilis MA-4680 1217621 NP_828689.1 CDS SAV_7513 NC_003155.4 8956405 8957319 R IS630 family, inserted IS900-like sequence. Inverted repeat sequence (11 bp). Target sequence (CTAG).; IS630 family transposase complement(8956405..8957319) Streptomyces avermitilis MA-4680 1217622 NP_828690.1 CDS SAV_7514 NC_003155.4 8957401 8958111 R WhiB-family transcriptional regulator complement(8957401..8958111) Streptomyces avermitilis MA-4680 1217623 NP_828691.1 CDS SAV_7515 NC_003155.4 8958230 8959000 R PF00990: GGDEF domain; hypothetical protein complement(8958230..8959000) Streptomyces avermitilis MA-4680 1217624 NP_828692.1 CDS spdB3 NC_003155.4 8959331 8959792 R mobile element transfer protein SpdB complement(8959331..8959792) Streptomyces avermitilis MA-4680 1211749 NP_828693.1 CDS SAV_7517 NC_003155.4 8960063 8960584 D hypothetical protein 8960063..8960584 Streptomyces avermitilis MA-4680 1217625 NP_828694.1 CDS SAV_7518 NC_003155.4 8960857 8961402 R hypothetical protein complement(8960857..8961402) Streptomyces avermitilis MA-4680 1217626 NP_828695.1 CDS SAV_7519 NC_003155.4 8961788 8961976 R hypothetical protein complement(8961788..8961976) Streptomyces avermitilis MA-4680 1217627 NP_828696.1 CDS traA2 NC_003155.4 8962072 8964507 R ATP/GTP-binding; major plasmid transfer protein complement(8962072..8964507) Streptomyces avermitilis MA-4680 1211750 NP_828697.1 CDS traB2 NC_003155.4 8964610 8965014 R plasmid transfer protein complement(8964610..8965014) Streptomyces avermitilis MA-4680 1211751 NP_828698.1 CDS SAV_7522 NC_003155.4 8965030 8967180 R hypothetical protein complement(8965030..8967180) Streptomyces avermitilis MA-4680 1217628 NP_828699.1 CDS SAV_7523 NC_003155.4 8967251 8967472 R hypothetical protein complement(8967251..8967472) Streptomyces avermitilis MA-4680 1217629 NP_828700.1 CDS SAV_7524 NC_003155.4 8967472 8967978 R PF00823: PPE family; hypothetical protein complement(8967472..8967978) Streptomyces avermitilis MA-4680 1217630 NP_828701.1 CDS SAV_7525 NC_003155.4 8968125 8969798 R PF06519: TolA protein; hypothetical protein complement(8968125..8969798) Streptomyces avermitilis MA-4680 1217631 NP_828702.1 CDS SAV_7526 NC_003155.4 8969957 8970757 R hypothetical protein complement(8969957..8970757) Streptomyces avermitilis MA-4680 1217632 NP_828703.1 CDS SAV_7527 NC_003155.4 8970898 8971074 R hypothetical protein complement(8970898..8971074) Streptomyces avermitilis MA-4680 1217633 NP_828704.1 CDS SAV_7528 NC_003155.4 8971212 8971946 R hypothetical protein complement(8971212..8971946) Streptomyces avermitilis MA-4680 1217634 NP_828705.1 CDS SAV_7529 NC_003155.4 8971904 8972464 R hypothetical protein complement(8971904..8972464) Streptomyces avermitilis MA-4680 1217635 NP_828706.1 CDS SAV_7530 NC_003155.4 8972843 8973172 D PF03992: Antibiotic biosynthesis monooxygenase; hypothetical protein 8972843..8973172 Streptomyces avermitilis MA-4680 1217636 NP_828707.1 CDS SAV_7531 NC_003155.4 8973169 8974422 D transcriptional regulator 8973169..8974422 Streptomyces avermitilis MA-4680 1217637 NP_828708.1 CDS SAV_7532 NC_003155.4 8974593 8975660 D P-loop ATPase 8974593..8975660 Streptomyces avermitilis MA-4680 1217638 NP_828709.1 CDS SAV_7533 NC_003155.4 8975657 8976229 D guanylate kinase 8975657..8976229 Streptomyces avermitilis MA-4680 1217639 NP_828710.1 CDS SAV_7534 NC_003155.4 8976231 8977073 R PF02153: Prephenate dehydrogenase; hypothetical protein complement(8976231..8977073) Streptomyces avermitilis MA-4680 1217640 NP_828711.1 CDS SAV_7535 NC_003155.4 8977078 8977725 R PF00702: haloacid dehalogenase-like hydrolase; hydrolase complement(8977078..8977725) Streptomyces avermitilis MA-4680 1217641 NP_828712.1 CDS SAV_7536 NC_003155.4 8978205 8981042 D hypothetical protein 8978205..8981042 Streptomyces avermitilis MA-4680 1217642 NP_828713.1 CDS SAV_7537 NC_003155.4 8984010 8985005 R hypothetical protein complement(8984010..8985005) Streptomyces avermitilis MA-4680 1217643 NP_828714.1 CDS SAV_7538 NC_003155.4 8985002 8985670 R hypothetical protein complement(8985002..8985670) Streptomyces avermitilis MA-4680 1217644 NP_828715.1 CDS SAV_7539 NC_003155.4 8985667 8986503 R hypothetical protein complement(8985667..8986503) Streptomyces avermitilis MA-4680 1217645 NP_828716.1 CDS SAV_7540 NC_003155.4 8986500 8987678 R hypothetical protein complement(8986500..8987678) Streptomyces avermitilis MA-4680 1217646 NP_828717.1 CDS SAV_7541 NC_003155.4 8987744 8988430 R hypothetical protein complement(8987744..8988430) Streptomyces avermitilis MA-4680 1217647 NP_828718.1 CDS SAV_7542 NC_003155.4 8988473 8990044 R hypothetical protein complement(8988473..8990044) Streptomyces avermitilis MA-4680 1217648 NP_828719.1 CDS SAV_7543 NC_003155.4 8990281 8993226 R helicase complement(8990281..8993226) Streptomyces avermitilis MA-4680 1217649 NP_828720.1 CDS SAV_7544 NC_003155.4 8994124 8994972 R hypothetical protein complement(8994124..8994972) Streptomyces avermitilis MA-4680 1217650 NP_828721.1 CDS SAV_7545 NC_003155.4 8997081 8998715 D IS6 family transposase 8997081..8998715 Streptomyces avermitilis MA-4680 1217651 NP_828722.1 CDS SAV_7546 NC_003155.4 8998805 8999614 R IS21 family, truncated; transposase complement(8998805..8999614) Streptomyces avermitilis MA-4680 1217652 NP_828723.1 CDS SAV_7547 NC_003155.4 8999611 9000852 R IS21 family, truncated; IS21 family transposase complement(8999611..9000852) Streptomyces avermitilis MA-4680 1217653 NP_828724.1 CDS SAV_7548 NC_003155.4 9000969 9002603 R IS6 family transposase complement(9000969..9002603) Streptomyces avermitilis MA-4680 1217654 NP_828725.1 CDS SAV_7549 NC_003155.4 9002895 9003203 R hypothetical protein complement(9002895..9003203) Streptomyces avermitilis MA-4680 1217655 NP_828726.1 CDS SAV_7551 NC_003155.4 9003252 9003410 R hypothetical protein complement(9003252..9003410) Streptomyces avermitilis MA-4680 1217656 NP_828727.1 CDS SAV_7550 NC_003155.4 9003392 9003574 D hypothetical protein 9003392..9003574 Streptomyces avermitilis MA-4680 1217657 NP_828728.1 CDS SAV_7552 NC_003155.4 9003581 9004177 D hypothetical protein 9003581..9004177 Streptomyces avermitilis MA-4680 1217658 NP_828729.1 CDS SAV_7553 NC_003155.4 9004239 9004721 D IS1647-like transposase 9004239..9004721 Streptomyces avermitilis MA-4680 1217659 NP_828730.1 CDS SAV_7554 NC_003155.4 9004613 9005056 D IS1647-like transposase 9004613..9005056 Streptomyces avermitilis MA-4680 1217660 NP_828731.1 CDS SAV_7555 NC_003155.4 9005159 9005944 D hypothetical protein 9005159..9005944 Streptomyces avermitilis MA-4680 1217661 NP_828732.1 CDS SAV_7556 NC_003155.4 9006357 9006758 R IS1648-like transposase complement(9006357..9006758) Streptomyces avermitilis MA-4680 1217662 NP_828733.1 CDS SAV_7557 NC_003155.4 9006906 9007151 D hypothetical protein 9006906..9007151 Streptomyces avermitilis MA-4680 1217663 NP_828734.1 CDS SAV_7558 NC_003155.4 9007287 9008051 D IS493-like transposase 9007287..9008051 Streptomyces avermitilis MA-4680 1217664 NP_828735.1 CDS SAV_7559 NC_003155.4 9008121 9008366 D hypothetical protein 9008121..9008366 Streptomyces avermitilis MA-4680 1217665 NP_828736.1 CDS SAV_7560 NC_003155.4 9008480 9008818 D hypothetical protein 9008480..9008818 Streptomyces avermitilis MA-4680 1217666 NP_828737.1 CDS SAV_7561 NC_003155.4 9009323 9012304 R PF05729: NACHT domain; hypothetical protein complement(9009323..9012304) Streptomyces avermitilis MA-4680 1217667 NP_828738.1 CDS SAV_7562 NC_003155.4 9012343 9012708 R hypothetical protein complement(9012343..9012708) Streptomyces avermitilis MA-4680 1217668 NP_828739.1 CDS SAV_7563 NC_003155.4 9012969 9013628 R PF00652: QXW lectin repeat; hypothetical protein complement(9012969..9013628) Streptomyces avermitilis MA-4680 1217669 NP_828740.1 CDS SAV_7564 NC_003155.4 9013686 9014216 D hypothetical protein 9013686..9014216 Streptomyces avermitilis MA-4680 1217670 NP_828741.1 CDS SAV_7565 NC_003155.4 9014686 9014829 R hypothetical protein complement(9014686..9014829) Streptomyces avermitilis MA-4680 1217671 NP_828742.1 CDS SAV_7566 NC_003155.4 9015100 9015510 R hypothetical protein complement(9015100..9015510) Streptomyces avermitilis MA-4680 1217672 NP_828743.2 CDS tapA1 NC_003155.4 9015719 9017959 D putative telomere-associated protein 9015719..9017959 Streptomyces avermitilis MA-4680 1211752 NP_828744.1 CDS tpgA1 NC_003155.4 9017972 9018529 D terminal protein TpgA1 9017972..9018529 Streptomyces avermitilis MA-4680 1211753 NP_828745.1 CDS SAV_7569 NC_003155.4 9019854 9020411 R IS630 family transposase complement(9019854..9020411) Streptomyces avermitilis MA-4680 1217673 NP_828746.1 CDS SAV_7570 NC_003155.4 9020408 9020947 R IS630 family transposase complement(9020408..9020947) Streptomyces avermitilis MA-4680 1217674 NP_828747.1 CDS SAV_7571 NC_003155.4 9021192 9023699 R helicase complement(9021192..9023699) Streptomyces avermitilis MA-4680 1217675 NP_828748.1 CDS SAV_7572 NC_003155.4 9023991 9024185 D hypothetical protein 9023991..9024185 Streptomyces avermitilis MA-4680 1217676 NP_828749.1 CDS SAV_7573 NC_003155.4 9024130 9024540 D hypothetical protein 9024130..9024540 Streptomyces avermitilis MA-4680 1217677 NP_828750.1 CDS SAP1p01 NC_004719.1 1197 1904 D SAP1_1; hypothetical protein 1197..1904 Streptomyces avermitilis MA-4680 2746965 NP_828751.1 CDS SAP1p02 NC_004719.1 1901 2377 D SAP1_2; hypothetical protein 1901..2377 Streptomyces avermitilis MA-4680 2746894 NP_828752.1 CDS SAP1p03 NC_004719.1 2490 2975 D SAP1_3; hypothetical protein 2490..2975 Streptomyces avermitilis MA-4680 2746901 NP_828753.1 CDS SAP1p04 NC_004719.1 4104 4619 R SAP1_4; hypothetical protein complement(4104..4619) Streptomyces avermitilis MA-4680 2746947 NP_828754.1 CDS SAP1p05 NC_004719.1 4639 4911 R SAP1_5; hypothetical protein complement(4639..4911) Streptomyces avermitilis MA-4680 2746942 NP_828755.1 CDS SAP1p06 NC_004719.1 4911 5144 R SAP1_6; hypothetical protein complement(4911..5144) Streptomyces avermitilis MA-4680 2746926 NP_828756.1 CDS SAP1p07 NC_004719.1 6495 7088 R SAP1_7; hypothetical protein complement(6495..7088) Streptomyces avermitilis MA-4680 2746943 NP_828757.1 CDS SAP1p08 NC_004719.1 7111 7851 D SAP1_8; putative transposase B-like protein 7111..7851 Streptomyces avermitilis MA-4680 2746934 NP_828758.1 CDS SAP1p09 NC_004719.1 8729 9040 R SAP1_9; hypothetical protein complement(8729..9040) Streptomyces avermitilis MA-4680 2746944 NP_828759.1 CDS SAP1p10 NC_004719.1 9260 9592 D SAP1_10; hypothetical protein 9260..9592 Streptomyces avermitilis MA-4680 2746885 NP_828760.1 CDS SAP1p11 NC_004719.1 9623 10216 R SAP1_11; hypothetical protein complement(9623..10216) Streptomyces avermitilis MA-4680 2746925 NP_828761.1 CDS SAP1p12 NC_004719.1 10346 10654 D SAP1_12; hypothetical protein 10346..10654 Streptomyces avermitilis MA-4680 2746920 NP_828762.1 CDS SAP1p13 NC_004719.1 10741 11103 D SAP1_13; hypothetical protein 10741..11103 Streptomyces avermitilis MA-4680 2746891 NP_828763.1 CDS SAP1p14 NC_004719.1 11106 11633 D SAP1_14; hypothetical protein 11106..11633 Streptomyces avermitilis MA-4680 2746896 NP_828764.1 CDS SAP1p15 NC_004719.1 11657 12223 R SAP1_15; hypothetical protein complement(11657..12223) Streptomyces avermitilis MA-4680 2746895 NP_828765.1 CDS SAP1p16 NC_004719.1 12286 13566 D SAP1_16; putative endonuclease VII 12286..13566 Streptomyces avermitilis MA-4680 2746918 NP_828766.1 CDS SAP1p17 NC_004719.1 13703 15061 R SAP1_17; hypothetical protein complement(13703..15061) Streptomyces avermitilis MA-4680 2746893 NP_828767.1 CDS SAP1p18 NC_004719.1 15071 17104 R SAP1_18; putative NHN endonuclease complement(15071..17104) Streptomyces avermitilis MA-4680 2746897 NP_828768.1 CDS SAP1p19 NC_004719.1 17560 18426 R SAP1_19; putative acetyltransferase complement(17560..18426) Streptomyces avermitilis MA-4680 2746908 NP_828769.1 CDS SAP1p20 NC_004719.1 18796 19674 D SAP1_20; hypothetical protein 18796..19674 Streptomyces avermitilis MA-4680 2746919 NP_828770.1 CDS tpgA2 NC_004719.1 19768 20325 R SAP1_21; putative terminal protein TpgA2 complement(19768..20325) Streptomyces avermitilis MA-4680 1210013 NP_828771.1 CDS SAP1p22 NC_004719.1 20338 22656 R SAP1_22; putative transcriptional regulatory protein complement(20338..22656) Streptomyces avermitilis MA-4680 2746890 NP_828772.1 CDS SAP1p23 NC_004719.1 22760 24598 D SAP1_23; putative DNA-binding protein 22760..24598 Streptomyces avermitilis MA-4680 2746887 NP_828773.1 CDS SAP1p24 NC_004719.1 24562 24840 R SAP1_24; hypothetical protein complement(24562..24840) Streptomyces avermitilis MA-4680 2746922 NP_828774.1 CDS SAP1p25 NC_004719.1 24871 25902 R SAP1_25; hypothetical protein complement(24871..25902) Streptomyces avermitilis MA-4680 2746962 NP_828775.1 CDS SAP1p26 NC_004719.1 25942 28617 D SAP1_26; putative DNA-binding protein 25942..28617 Streptomyces avermitilis MA-4680 2746954 NP_828776.1 CDS SAP1p27 NC_004719.1 28671 29051 R SAP1_27; hypothetical protein complement(28671..29051) Streptomyces avermitilis MA-4680 2746914 NP_828777.1 CDS SAP1p28 NC_004719.1 29048 29407 R SAP1_28; hypothetical protein complement(29048..29407) Streptomyces avermitilis MA-4680 2746958 NP_828778.1 CDS SAP1p29 NC_004719.1 29812 31962 R SAP1_29; hypothetical protein complement(29812..31962) Streptomyces avermitilis MA-4680 2746969 NP_828779.1 CDS SAP1p30 NC_004719.1 32033 32203 D SAP1_30; hypothetical protein 32033..32203 Streptomyces avermitilis MA-4680 2746899 NP_828780.1 CDS SAP1p31 NC_004719.1 32340 33533 R SAP1_31; putative serine/threonine protein kinase complement(32340..33533) Streptomyces avermitilis MA-4680 2746930 NP_828781.1 CDS SAP1p32 NC_004719.1 33610 33942 R SAP1_32; putative Tra3 protein complement(33610..33942) Streptomyces avermitilis MA-4680 2746932 NP_828782.1 CDS SAP1p33 NC_004719.1 34010 37012 D SAP1_33; hypothetical protein 34010..37012 Streptomyces avermitilis MA-4680 2746931 NP_828783.1 CDS SAP1p34 NC_004719.1 37072 37557 R SAP1_34; putative Tra3-like protein complement(37072..37557) Streptomyces avermitilis MA-4680 2746929 NP_828784.1 CDS SAP1p35 NC_004719.1 37554 39374 R SAP1_35; hypothetical protein complement(37554..39374) Streptomyces avermitilis MA-4680 2746915 NP_828785.1 CDS SAP1p36 NC_004719.1 40645 41325 R SAP1_36; putative riboflavin-specific deaminase/reductase complement(40645..41325) Streptomyces avermitilis MA-4680 2746916 NP_828786.1 CDS SAP1p37 NC_004719.1 41330 42763 R SAP1_37; putative DNA-binding protein complement(41330..42763) Streptomyces avermitilis MA-4680 2746951 NP_828787.1 CDS SAP1p38 NC_004719.1 42887 43690 R SAP1_38; GntR family transcriptional regulator complement(42887..43690) Streptomyces avermitilis MA-4680 2746941 NP_828788.1 CDS SAP1p39 NC_004719.1 43843 44643 D SAP1_39; hypothetical protein 43843..44643 Streptomyces avermitilis MA-4680 2746923 NP_828789.1 CDS SAP1p40 NC_004719.1 44778 45344 D SAP1_40; putative regulatory protein 44778..45344 Streptomyces avermitilis MA-4680 2746924 NP_828790.1 CDS SAP1p41 NC_004719.1 45428 45745 D SAP1_41; putative regulatory protein 45428..45745 Streptomyces avermitilis MA-4680 2746961 NP_828791.1 CDS SAP1p42 NC_004719.1 45889 46146 D SAP1_42; hypothetical protein 45889..46146 Streptomyces avermitilis MA-4680 2746949 NP_828792.1 CDS SAP1p43 NC_004719.1 46230 46616 D SAP1_43; hypothetical protein 46230..46616 Streptomyces avermitilis MA-4680 2746880 NP_828793.1 CDS SAP1p44 NC_004719.1 46672 48876 D SAP1_44; putative large alanine-rich protein 46672..48876 Streptomyces avermitilis MA-4680 2746945 NP_828794.1 CDS SAP1p45 NC_004719.1 48992 49468 D SAP1_45; hypothetical protein 48992..49468 Streptomyces avermitilis MA-4680 2746946 NP_828795.1 CDS SAP1p46 NC_004719.1 49465 49773 D SAP1_46; hypothetical protein 49465..49773 Streptomyces avermitilis MA-4680 2746928 NP_828796.1 CDS SAP1p47 NC_004719.1 49901 52117 D SAP1_47; putative ATP/GTP-binding Gly/Ala-rich protein 49901..52117 Streptomyces avermitilis MA-4680 2746903 NP_828797.1 CDS traB NC_004719.1 52137 52553 D SAP1_48; putative TraB protein 52137..52553 Streptomyces avermitilis MA-4680 1210015 NP_828798.1 CDS traA NC_004719.1 52635 54779 D SAP1_49; putative TraA protein 52635..54779 Streptomyces avermitilis MA-4680 1210014 NP_828799.1 CDS SAP1p50 NC_004719.1 54860 55048 D SAP1_50; hypothetical protein 54860..55048 Streptomyces avermitilis MA-4680 2746917 NP_828800.1 CDS SAP1p51 NC_004719.1 55049 55303 R SAP1_51; hypothetical protein complement(55049..55303) Streptomyces avermitilis MA-4680 2746905 NP_828801.1 CDS SAP1p52 NC_004719.1 55435 55929 D SAP1_52; hypothetical protein 55435..55929 Streptomyces avermitilis MA-4680 2746906 NP_828802.1 CDS SAP1p53 NC_004719.1 55992 56792 D SAP1_53; hypothetical protein 55992..56792 Streptomyces avermitilis MA-4680 2746892 NP_828803.1 CDS SAP1p54 NC_004719.1 56873 57118 D SAP1_54; hypothetical protein 56873..57118 Streptomyces avermitilis MA-4680 2746889 NP_828804.1 CDS SAP1p55 NC_004719.1 57364 57831 D SAP1_55; hypothetical protein 57364..57831 Streptomyces avermitilis MA-4680 2746900 NP_828805.1 CDS SAP1p56 NC_004719.1 57828 58457 D SAP1_56; hypothetical protein 57828..58457 Streptomyces avermitilis MA-4680 2746956 NP_828806.1 CDS SAP1p57 NC_004719.1 58454 58804 D SAP1_57; hypothetical protein 58454..58804 Streptomyces avermitilis MA-4680 2746952 NP_828807.1 CDS SAP1p58 NC_004719.1 58801 59757 D SAP1_58; putative ATP/GTP-binding protein 58801..59757 Streptomyces avermitilis MA-4680 2746967 NP_828808.1 CDS SAP1p59 NC_004719.1 60014 60370 D SAP1_59; hypothetical protein 60014..60370 Streptomyces avermitilis MA-4680 2746953 NP_828809.1 CDS SAP1p60 NC_004719.1 60537 60980 D SAP1_60; hypothetical protein 60537..60980 Streptomyces avermitilis MA-4680 2746910 NP_828810.1 CDS SAP1p61 NC_004719.1 60977 61258 D SAP1_61; hypothetical protein 60977..61258 Streptomyces avermitilis MA-4680 2746909 NP_828811.1 CDS SAP1p62 NC_004719.1 61281 61454 D SAP1_62; hypothetical protein 61281..61454 Streptomyces avermitilis MA-4680 2746955 NP_828812.1 CDS SAP1p63 NC_004719.1 61468 62430 D SAP1_63; hypothetical protein 61468..62430 Streptomyces avermitilis MA-4680 2746921 NP_828813.1 CDS SAP1p64 NC_004719.1 62451 62912 R SAP1_64; putative acetyltransferase complement(62451..62912) Streptomyces avermitilis MA-4680 2746907 NP_828814.1 CDS SAP1p65 NC_004719.1 63009 64202 R SAP1_65; IS116/IS110/IS902 family transposase complement(63009..64202) Streptomyces avermitilis MA-4680 2746959 NP_828815.1 CDS SAP1p66 NC_004719.1 64439 65188 D SAP1_66; hypothetical protein 64439..65188 Streptomyces avermitilis MA-4680 2746904 NP_828816.1 CDS SAP1p67 NC_004719.1 65221 65397 D SAP1_67; hypothetical protein 65221..65397 Streptomyces avermitilis MA-4680 2746966 NP_828817.1 CDS SAP1p68 NC_004719.1 65485 65925 D SAP1_68; hypothetical protein 65485..65925 Streptomyces avermitilis MA-4680 2746950 NP_828818.1 CDS SAP1p69 NC_004719.1 65922 66545 D SAP1_69; hypothetical protein 65922..66545 Streptomyces avermitilis MA-4680 2746960 NP_828819.1 CDS parB NC_004719.1 66759 67790 R ParB nuclease; SAP1_70; putative plasmid partitioning protein complement(66759..67790) Streptomyces avermitilis MA-4680 1210012 NP_828820.1 CDS parA NC_004719.1 67787 69070 R ParA ATPase; SAP1_71; putative plasmid partitioning protein complement(67787..69070) Streptomyces avermitilis MA-4680 1210011 NP_828821.1 CDS SAP1p72 NC_004719.1 69221 70444 D SAP1_72; hypothetical protein 69221..70444 Streptomyces avermitilis MA-4680 2746968 NP_828822.1 CDS SAP1p73 NC_004719.1 70500 71348 R SAP1_73; hypothetical protein complement(70500..71348) Streptomyces avermitilis MA-4680 2746912 NP_828823.1 CDS SAP1p74 NC_004719.1 71473 72894 D SAP1_74; hypothetical protein 71473..72894 Streptomyces avermitilis MA-4680 2746913 NP_828824.1 CDS SAP1p75 NC_004719.1 73370 75196 D SAP1_75; putative TraA-like protein 73370..75196 Streptomyces avermitilis MA-4680 2746902 NP_828825.1 CDS SAP1p76 NC_004719.1 75193 75540 D SAP1_76; hypothetical protein 75193..75540 Streptomyces avermitilis MA-4680 2746898 NP_828826.1 CDS SAP1p77 NC_004719.1 75821 76372 R SAP1_77; MarR family transcriptional regulator complement(75821..76372) Streptomyces avermitilis MA-4680 2746911 NP_828827.1 CDS SAP1p78 NC_004719.1 76391 76693 R SAP1_78; hypothetical protein complement(76391..76693) Streptomyces avermitilis MA-4680 2746940 NP_828828.1 CDS SAP1p79 NC_004719.1 77122 77331 R SAP1_79; hypothetical protein complement(77122..77331) Streptomyces avermitilis MA-4680 2746888 NP_828829.1 CDS SAP1p80 NC_004719.1 77375 77812 R SAP1_80; hypothetical protein complement(77375..77812) Streptomyces avermitilis MA-4680 2746939 NP_828830.1 CDS SAP1p81 NC_004719.1 77865 78545 D SAP1_81; hypothetical protein 77865..78545 Streptomyces avermitilis MA-4680 2746957 NP_828831.1 CDS SAP1p82 NC_004719.1 78662 79711 D SAP1_82; hypothetical protein 78662..79711 Streptomyces avermitilis MA-4680 2746963 NP_828832.1 CDS SAP1p83 NC_004719.1 79927 80568 D SAP1_83; hypothetical protein 79927..80568 Streptomyces avermitilis MA-4680 2746883 NP_828833.1 CDS SAP1p84 NC_004719.1 80518 81579 R SAP1_84; hypothetical protein complement(80518..81579) Streptomyces avermitilis MA-4680 2746884 NP_828834.1 CDS SAP1p85 NC_004719.1 81600 81701 D SAP1_85; hypothetical protein 81600..81701 Streptomyces avermitilis MA-4680 2746936 NP_828835.1 CDS SAP1p86 NC_004719.1 81711 81926 D SAP1_86; hypothetical protein 81711..81926 Streptomyces avermitilis MA-4680 2746881 NP_828836.1 CDS SAP1p87 NC_004719.1 81923 82828 D SAP1_87; putative RNA polymerase sigma factor 81923..82828 Streptomyces avermitilis MA-4680 2746948 NP_828837.1 CDS SAP1p88 NC_004719.1 82825 83700 D SAP1_88; hypothetical protein 82825..83700 Streptomyces avermitilis MA-4680 2746935 NP_828838.1 CDS SAP1p89 NC_004719.1 83768 84670 R SAP1_89; hypothetical protein complement(83768..84670) Streptomyces avermitilis MA-4680 2746882 NP_828839.1 CDS lig NC_004719.1 85072 86049 R SAP1_90; putative ATP-dependint DNA ligase complement(85072..86049) Streptomyces avermitilis MA-4680 1210010 NP_828840.1 CDS SAP1p91 NC_004719.1 86243 86371 R SAP1_91; hypothetical protein complement(86243..86371) Streptomyces avermitilis MA-4680 2746927 NP_828841.1 CDS SAP1p92 NC_004719.1 86514 87095 D SAP1_92; hypothetical protein 86514..87095 Streptomyces avermitilis MA-4680 2746964 NP_828842.1 CDS SAP1p93 NC_004719.1 87433 89484 D SAP1_93; putative DNA mismatch repair protein 87433..89484 Streptomyces avermitilis MA-4680 2746938 NP_828843.1 CDS SAP1p94 NC_004719.1 89669 90514 D SAP1_94; putative dioxygenase 89669..90514 Streptomyces avermitilis MA-4680 2746933 NP_828844.1 CDS SAP1p95 NC_004719.1 90591 93248 R SAP1_95; putative helicase complement(90591..93248) Streptomyces avermitilis MA-4680 2746886 NP_828845.1 CDS SAP1p96 NC_004719.1 93292 93669 R SAP1_96; hypothetical protein complement(93292..93669) Streptomyces avermitilis MA-4680 2746937 SAV_t1 tRNA trn1 NC_003155.4 357776 357847 D tRNA-Val 357776..357847 Streptomyces avermitilis MA-4680 1210020 SAV_t2 tRNA trn2 NC_003155.4 1675869 1675942 D tRNA-Met 1675869..1675942 Streptomyces avermitilis MA-4680 1210188 SAV_t3 tRNA trn68 NC_003155.4 1965347 1965423 R tRNA-Pro complement(1965347..1965423) Streptomyces avermitilis MA-4680 1210226 SAV_t4 tRNA trn67 NC_003155.4 1992012 1992088 R tRNA-Pro complement(1992012..1992088) Streptomyces avermitilis MA-4680 1210234 SAV_t5 tRNA trn66 NC_003155.4 2222599 2222686 R tRNA-Leu complement(2222599..2222686) Streptomyces avermitilis MA-4680 1210287 SAV_t6 tRNA trn65 NC_003155.4 3072632 3072707 R tRNA-Thr complement(3072632..3072707) Streptomyces avermitilis MA-4680 1210451 SAV_t7 tRNA trn64 NC_003155.4 3295252 3295324 R tRNA-Glu complement(3295252..3295324) Streptomyces avermitilis MA-4680 1210513 SAV_t8 tRNA trn63 NC_003155.4 3295345 3295416 R tRNA-Gln complement(3295345..3295416) Streptomyces avermitilis MA-4680 1210514 SAV_t9 tRNA trn62 NC_003155.4 3295438 3295510 R tRNA-Glu complement(3295438..3295510) Streptomyces avermitilis MA-4680 1210515 SAV_t10 tRNA trn61 NC_003155.4 3295573 3295645 R tRNA-Glu complement(3295573..3295645) Streptomyces avermitilis MA-4680 1210516 SAV_t11 tRNA trn60 NC_003155.4 3295688 3295759 R tRNA-Gln complement(3295688..3295759) Streptomyces avermitilis MA-4680 1210517 SAV_t12 tRNA trn3 NC_003155.4 3655871 3655942 D tRNA-Arg 3655871..3655942 Streptomyces avermitilis MA-4680 1210610 SAV_t13 tRNA trn59 NC_003155.4 3813093 3813166 R tRNA-Met complement(3813093..3813166) Streptomyces avermitilis MA-4680 1210656 SAV_t14 tRNA trn58 NC_003155.4 3815456 3815530 R tRNA-Met complement(3815456..3815530) Streptomyces avermitilis MA-4680 1210657 SAV_t15 tRNA trn57 NC_003155.4 4362610 4362695 R tRNA-Leu complement(4362610..4362695) Streptomyces avermitilis MA-4680 1210758 SAV_t16 tRNA trn4 NC_003155.4 4410534 4410608 D tRNA-Gln 4410534..4410608 Streptomyces avermitilis MA-4680 1210764 SAV_t17 tRNA trn56 NC_003155.4 4542466 4542542 R tRNA-Ala complement(4542466..4542542) Streptomyces avermitilis MA-4680 1210787 SAV_t18 tRNA trn5 NC_003155.4 4589760 4589835 D tRNA-Arg 4589760..4589835 Streptomyces avermitilis MA-4680 1210801 SAV_t19 tRNA trn55 NC_003155.4 4886830 4886906 R tRNA-Thr complement(4886830..4886906) Streptomyces avermitilis MA-4680 1210848 SAV_t20 tRNA trn54 NC_003155.4 5051970 5052043 R tRNA-Met complement(5051970..5052043) Streptomyces avermitilis MA-4680 1210878 SAV_t21 tRNA trn53 NC_003155.4 5055486 5055561 R tRNA-Lys complement(5055486..5055561) Streptomyces avermitilis MA-4680 1210881 SAV_t22 tRNA trn6 NC_003155.4 5063087 5063159 D tRNA-Glu 5063087..5063159 Streptomyces avermitilis MA-4680 1210882 SAV_t23 tRNA trn7 NC_003155.4 5063207 5063281 D tRNA-Asp 5063207..5063281 Streptomyces avermitilis MA-4680 1210883 SAV_t24 tRNA trn8 NC_003155.4 5063306 5063382 D tRNA-Phe 5063306..5063382 Streptomyces avermitilis MA-4680 1210884 SAV_t25 tRNA trn9 NC_003155.4 5068123 5068197 D tRNA-Asp 5068123..5068197 Streptomyces avermitilis MA-4680 1210886 SAV_t26 tRNA trn10 NC_003155.4 5081791 5081866 D tRNA-Gly 5081791..5081866 Streptomyces avermitilis MA-4680 1210892 SAV_t27 tRNA trn11 NC_003155.4 5085779 5085854 D tRNA-Gly 5085779..5085854 Streptomyces avermitilis MA-4680 1210893 SAV_t28 tRNA trn12 NC_003155.4 5095224 5095311 D tRNA-Ser 5095224..5095311 Streptomyces avermitilis MA-4680 1210897 SAV_t29 tRNA trn13 NC_003155.4 5129698 5129782 D tRNA-Ser 5129698..5129782 Streptomyces avermitilis MA-4680 1210900 SAV_t30 tRNA trn52 NC_003155.4 5154937 5155009 R tRNA-Arg complement(5154937..5155009) Streptomyces avermitilis MA-4680 1210903 SAV_t31 tRNA trn51 NC_003155.4 5155215 5155305 R tRNA-Ser complement(5155215..5155305) Streptomyces avermitilis MA-4680 1210904 SAV_t32 tRNA trn50 NC_003155.4 5177691 5177777 R tRNA-Ser complement(5177691..5177777) Streptomyces avermitilis MA-4680 1210910 SAV_t33 tRNA trn49 NC_003155.4 5206939 5207028 R tRNA-Ser complement(5206939..5207028) Streptomyces avermitilis MA-4680 1210916 SAV_t34 tRNA trn14 NC_003155.4 5299302 5299378 D tRNA-Ile 5299302..5299378 Streptomyces avermitilis MA-4680 1210953 SAV_t35 tRNA trn15 NC_003155.4 5304905 5304977 D tRNA-Ala 5304905..5304977 Streptomyces avermitilis MA-4680 1210955 SAV_t36 tRNA trn16 NC_003155.4 5322106 5322192 D tRNA-Leu 5322106..5322192 Streptomyces avermitilis MA-4680 1210962 SAV_t37 tRNA trn48 NC_003155.4 5452769 5452842 R tRNA-Gly complement(5452769..5452842) Streptomyces avermitilis MA-4680 1210993 SAV_t38 tRNA trn47 NC_003155.4 5594481 5594554 R tRNA-Pro complement(5594481..5594554) Streptomyces avermitilis MA-4680 1211015 SAV_t39 tRNA trn17 NC_003155.4 5650316 5650389 D tRNA-Thr 5650316..5650389 Streptomyces avermitilis MA-4680 1211027 SAV_t40 tRNA trn18 NC_003155.4 5950170 5950251 D tRNA-Tyr 5950170..5950251 Streptomyces avermitilis MA-4680 1211108 SAV_t41 tRNA trn19 NC_003155.4 5956602 5956674 D tRNA-Thr 5956602..5956674 Streptomyces avermitilis MA-4680 1211109 SAV_t42 tRNA trn20 NC_003155.4 5956721 5956793 D tRNA-Met 5956721..5956793 Streptomyces avermitilis MA-4680 1211110 SAV_t43 tRNA trn21 NC_003155.4 5964532 5964607 D tRNA-Trp 5964532..5964607 Streptomyces avermitilis MA-4680 1211115 SAV_t44 tRNA trn46 NC_003155.4 6242261 6242335 R tRNA-Cys complement(6242261..6242335) Streptomyces avermitilis MA-4680 1211210 SAV_t45 tRNA trn45 NC_003155.4 6279029 6279112 R tRNA-Leu complement(6279029..6279112) Streptomyces avermitilis MA-4680 1211220 SAV_t46 tRNA trn44 NC_003155.4 6329202 6329278 R tRNA-Lys complement(6329202..6329278) Streptomyces avermitilis MA-4680 1211225 SAV_t47 tRNA trn43 NC_003155.4 6335068 6335141 R tRNA-Lys complement(6335068..6335141) Streptomyces avermitilis MA-4680 1211228 SAV_t48 tRNA trn42 NC_003155.4 6349312 6349385 R tRNA-Lys complement(6349312..6349385) Streptomyces avermitilis MA-4680 1211229 SAV_t49 tRNA trn41 NC_003155.4 6372705 6372777 R tRNA-His complement(6372705..6372777) Streptomyces avermitilis MA-4680 1211230 SAV_t50 tRNA trn40 NC_003155.4 6501509 6501584 R tRNA-Arg complement(6501509..6501584) Streptomyces avermitilis MA-4680 1211262 SAV_t51 tRNA trn39 NC_003155.4 6604435 6604508 R tRNA-Gly complement(6604435..6604508) Streptomyces avermitilis MA-4680 1211273 SAV_t52 tRNA trn22 NC_003155.4 6604662 6604738 D tRNA-Pro 6604662..6604738 Streptomyces avermitilis MA-4680 1211274 SAV_t53 tRNA trn23 NC_003155.4 6653846 6653918 D tRNA-Ala 6653846..6653918 Streptomyces avermitilis MA-4680 1211294 SAV_t54 tRNA trn24 NC_003155.4 6658303 6658375 D tRNA-Ala 6658303..6658375 Streptomyces avermitilis MA-4680 1211295 SAV_t55 tRNA trn25 NC_003155.4 6875603 6875675 D tRNA-Asn 6875603..6875675 Streptomyces avermitilis MA-4680 1211329 SAV_t56 tRNA trn26 NC_003155.4 6875681 6875753 D tRNA-Asn 6875681..6875753 Streptomyces avermitilis MA-4680 1211330 SAV_t57 tRNA trn27 NC_003155.4 6875920 6875996 D tRNA-Met 6875920..6875996 Streptomyces avermitilis MA-4680 1211331 SAV_t58 tRNA trn28 NC_003155.4 7021984 7022058 D tRNA-Val 7021984..7022058 Streptomyces avermitilis MA-4680 1211348 SAV_t59 tRNA trn38 NC_003155.4 7471270 7471342 R tRNA-Leu complement(7471270..7471342) Streptomyces avermitilis MA-4680 1211437 SAV_t60 tRNA trn37 NC_003155.4 7937463 7937550 R tRNA-Leu complement(7937463..7937550) Streptomyces avermitilis MA-4680 1211522 SAV_t61 tRNA trn36 NC_003155.4 8122352 8122426 R tRNA-Val complement(8122352..8122426) Streptomyces avermitilis MA-4680 1211568 SAV_t62 tRNA trn35 NC_003155.4 8122467 8122538 R tRNA-Val complement(8122467..8122538) Streptomyces avermitilis MA-4680 1211569 SAV_t63 tRNA trn34 NC_003155.4 8122558 8122629 R tRNA-Val complement(8122558..8122629) Streptomyces avermitilis MA-4680 1211570 SAV_t64 tRNA trn33 NC_003155.4 8122631 8122704 R tRNA-Cys complement(8122631..8122704) Streptomyces avermitilis MA-4680 1211571 SAV_t65 tRNA trn32 NC_003155.4 8122743 8122815 R tRNA-Gly complement(8122743..8122815) Streptomyces avermitilis MA-4680 1211572 SAV_t66 tRNA trn29 NC_003155.4 8129564 8129635 D tRNA-Val 8129564..8129635 Streptomyces avermitilis MA-4680 1211574 SAV_t67 tRNA trn30 NC_003155.4 8139938 8140012 D tRNA-Val 8139938..8140012 Streptomyces avermitilis MA-4680 1211575 SAV_t68 tRNA trn31 NC_003155.4 8576989 8577062 D tRNA-Pro 8576989..8577062 Streptomyces avermitilis MA-4680 1211689 SAV_r1 rRNA rrnA3 NC_003155.4 3073559 3073684 R 5S ribosomal RNA complement(3073559..3073684) Streptomyces avermitilis MA-4680 1210452 SAV_r2 rRNA rrnA2 NC_003155.4 3073772 3076895 R 23S ribosomal RNA complement(3073772..3076895) Streptomyces avermitilis MA-4680 1210453 SAV_r3 rRNA rrnA1 NC_003155.4 3077206 3078735 R 16S ribosomal RNA complement(3077206..3078735) Streptomyces avermitilis MA-4680 1210454 SAV_r4 rRNA rrnB3 NC_003155.4 5024100 5024225 R 5S ribosomal RNA complement(5024100..5024225) Streptomyces avermitilis MA-4680 1210874 SAV_r5 rRNA rrnB2 NC_003155.4 5024313 5027435 R 23S ribosomal RNA complement(5024313..5027435) Streptomyces avermitilis MA-4680 1210875 SAV_r6 rRNA rrnB1 NC_003155.4 5027746 5029275 R 16S ribosomal RNA complement(5027746..5029275) Streptomyces avermitilis MA-4680 1210876 SAV_r7 rRNA rrnC1 NC_003155.4 5759344 5760873 D 16S ribosomal RNA 5759344..5760873 Streptomyces avermitilis MA-4680 1211056 SAV_r8 rRNA rrnC2 NC_003155.4 5761184 5764306 D 23S ribosomal RNA 5761184..5764306 Streptomyces avermitilis MA-4680 1211057 SAV_r9 rRNA rrnC3 NC_003155.4 5764394 5764519 D 5S ribosomal RNA 5764394..5764519 Streptomyces avermitilis MA-4680 1211058 SAV_r10 rRNA rrnD1 NC_003155.4 6124388 6125917 D 16S ribosomal RNA 6124388..6125917 Streptomyces avermitilis MA-4680 1211190 SAV_r11 rRNA rrnD2 NC_003155.4 6126228 6129350 D 23S ribosomal RNA 6126228..6129350 Streptomyces avermitilis MA-4680 1211191 SAV_r12 rRNA rrnD3 NC_003155.4 6129438 6129563 D 5S ribosomal RNA 6129438..6129563 Streptomyces avermitilis MA-4680 1211192 SAV_r13 rRNA rrnE1 NC_003155.4 7765515 7767044 D 16S ribosomal RNA 7765515..7767044 Streptomyces avermitilis MA-4680 1211494 SAV_r14 rRNA rrnE2 NC_003155.4 7767351 7770474 D 23S ribosomal RNA 7767351..7770474 Streptomyces avermitilis MA-4680 1211495 SAV_r15 rRNA rrnE3 NC_003155.4 7770611 7770736 D 5S ribosomal RNA 7770611..7770736 Streptomyces avermitilis MA-4680 1211496 SAV_r16 rRNA rrnF1 NC_003155.4 8328598 8330127 D 16S ribosomal RNA 8328598..8330127 Streptomyces avermitilis MA-4680 1211637 SAV_r17 rRNA rrnF2 NC_003155.4 8330438 8333560 D 23S ribosomal RNA 8330438..8333560 Streptomyces avermitilis MA-4680 1211638 SAV_r18 rRNA rrnF3 NC_003155.4 8333648 8333773 D 5S ribosomal RNA 8333648..8333773 Streptomyces avermitilis MA-4680 1211639