-- dump date 20120504_163630 -- class Genbank::CDS -- table cds_note -- id note YP_001226257.1 binds the polymerase to DNA and acts as a sliding clamp YP_001226259.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001226260.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001226261.1 DNA replication, recombination, and repair YP_001226263.1 Energy production and conversion YP_001226266.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001226267.1 Intracellular trafficking and secretion YP_001226268.1 Signal transduction mechanisms / Transcription YP_001226269.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001226270.1 General function prediction only YP_001226271.1 Translation, ribosomal structure and biogenesis YP_001226272.1 Posttranslational modification, protein turnover, chaperones YP_001226273.1 General function prediction only YP_001226277.1 Posttranslational modification, protein turnover, chaperones YP_001226278.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001226280.1 General function prediction only YP_001226281.1 Function unknown YP_001226282.1 Cell envelope biogenesis, outer membrane YP_001226283.1 Cell envelope biogenesis, outer membrane YP_001226284.1 Carbohydrate transport and metabolism YP_001226285.1 Coenzyme metabolism YP_001226286.1 Posttranslational modification, protein turnover, chaperones YP_001226287.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001226288.1 Lipid metabolism YP_001226289.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001226294.1 Transcription / DNA replication, recombination, and repair YP_001226298.1 DNA replication, recombination, and repair YP_001226299.1 DNA replication, recombination, and repair YP_001226304.1 Coenzyme metabolism YP_001226305.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001226310.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226312.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001226315.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001226316.1 Translation, ribosomal structure and biogenesis YP_001226318.1 Cell envelope biogenesis, outer membrane YP_001226319.1 DNA replication, recombination, and repair YP_001226321.1 binds and unfolds substrates as part of the ClpXP protease YP_001226322.1 Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion YP_001226323.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001226324.1 Amino acid transport and metabolism YP_001226325.1 Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane YP_001226328.1 Translation, ribosomal structure and biogenesis YP_001226330.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001226331.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP YP_001226332.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001226333.1 Coenzyme metabolism YP_001226334.1 Low identity with RCC0315; DNA replication, recombination, and repair YP_001226335.1 controls the interaction of photosystem II cores with light-harvesting antenna YP_001226336.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001226337.1 Cell envelope biogenesis, outer membrane YP_001226338.1 Cell envelope biogenesis, outer membrane YP_001226339.1 Cell envelope biogenesis, outer membrane YP_001226340.1 Cell envelope biogenesis, outer membrane YP_001226342.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001226343.1 Amino acid transport and metabolism YP_001226344.1 Transcription YP_001226345.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001226346.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001226347.1 Translation, ribosomal structure and biogenesis YP_001226348.1 negatively supercoils closed circular double-stranded DNA YP_001226350.1 DNA replication, recombination, and repair YP_001226351.1 DNA replication, recombination, and repair YP_001226352.1 Posttranslational modification, protein turnover, chaperones YP_001226353.1 Inorganic ion transport and metabolism YP_001226354.1 Transcription YP_001226359.1 DNA replication, recombination, and repair YP_001226360.1 Carbohydrate transport and metabolism YP_001226362.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001226364.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001226365.1 functions in MreBCD complex in some organisms YP_001226366.1 Cell division and chromosome partitioning YP_001226368.1 Carbohydrate transport and metabolism YP_001226369.1 Signal transduction mechanisms / Transcription YP_001226370.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001226377.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001226378.1 General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair YP_001226379.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001226380.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001226385.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001226386.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001226387.1 Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism YP_001226388.1 Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism YP_001226389.1 part of the core of the reaction center of photosystem I YP_001226390.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001226391.1 Translation, ribosomal structure and biogenesis YP_001226393.1 Transcription YP_001226396.1 Carbohydrate transport and metabolism YP_001226397.1 Posttranslational modification, protein turnover, chaperones YP_001226402.1 Energy production and conversion YP_001226404.1 Energy production and conversion YP_001226405.1 Posttranslational modification, protein turnover, chaperones YP_001226409.1 Converts isocitrate to alpha ketoglutarate YP_001226411.1 Inorganic ion transport and metabolism YP_001226413.1 Defense mechanisms YP_001226414.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001226415.1 Cell envelope biogenesis, outer membrane YP_001226416.1 Amino acid transport and metabolism YP_001226419.1 General function prediction only YP_001226420.1 Translation, ribosomal structure and biogenesis YP_001226424.1 Possible frameshift with RCC0171 YP_001226425.1 Possible frameshift with RCC0170; Cell envelope biogenesis, outer membrane YP_001226426.1 Cell envelope biogenesis, outer membrane YP_001226428.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226429.1 Cell envelope biogenesis, outer membrane YP_001226430.1 Cell envelope biogenesis, outer membrane YP_001226431.1 Amino acid transport and metabolism YP_001226432.1 Cell envelope biogenesis, outer membrane YP_001226433.1 Cell envelope biogenesis, outer membrane YP_001226434.1 Cell envelope biogenesis, outer membrane YP_001226435.1 Cell envelope biogenesis, outer membrane YP_001226436.1 Defense mechanisms YP_001226438.1 Cell envelope biogenesis, outer membrane YP_001226439.1 Cell envelope biogenesis, outer membrane YP_001226441.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226442.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226443.1 Cell envelope biogenesis, outer membrane YP_001226448.1 Defense mechanisms YP_001226449.1 Cell envelope biogenesis, outer membrane YP_001226450.1 Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism YP_001226451.1 Possible pseudogene YP_001226452.1 Cell envelope biogenesis, outer membrane YP_001226460.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226461.1 Cell envelope biogenesis, outer membrane YP_001226462.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226463.1 may be involved in assembling and maintaining PSII complexes in the thylakoid membrane YP_001226464.1 may have a role in PSII core assembly, maintaining PSII dimers and donor side electron transfer YP_001226465.1 photosystem II reaction center subunit VI; associated with the reaction center of photosystem II YP_001226466.1 photosystem II reaction center subunit VI; associated with the reaction center of photosystem II YP_001226467.1 similar to Arabidopsis thaliana photosystem II assembly protein YP_001226469.1 Catalyzes the transfer of electrons from NADH to quinone YP_001226470.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001226471.1 catalyzes the transfer of electrons from NADH to quinones YP_001226473.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226474.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001226477.1 Photosynthesis YP_001226478.1 DNA replication, recombination, and repair YP_001226479.1 Coenzyme metabolism YP_001226480.1 Very low identity with RCC01407; DNA replication, recombination, and repair YP_001226481.1 DNA replication, recombination, and repair YP_001226482.1 Transcription YP_001226483.1 Amino acid transport and metabolism YP_001226484.1 Carbohydrate transport and metabolism YP_001226487.1 Shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain YP_001226488.1 Cell envelope biogenesis, outer membrane YP_001226489.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001226491.1 Transcription YP_001226494.1 Lipid metabolism YP_001226495.1 Lipid metabolism YP_001226498.1 Translation, ribosomal structure and biogenesis YP_001226502.1 Lipid metabolism YP_001226503.1 Lipid metabolism YP_001226504.1 Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism YP_001226505.1 Lipid metabolism YP_001226506.1 Signal transduction mechanisms / Transcription YP_001226507.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001226508.1 Photosynthesis YP_001226509.1 Copper efflux; Inorganic ion transport and metabolism YP_001226510.1 Nucleotide transport and metabolism YP_001226511.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001226512.1 Signal transduction mechanisms / Transcription YP_001226515.1 Photosynthesis YP_001226518.1 Cell envelope biogenesis, outer membrane YP_001226519.1 Cell envelope biogenesis, outer membrane YP_001226523.1 Amino acid transport and metabolism YP_001226524.1 Posttranslational modification, protein turnover, chaperones YP_001226531.1 Lipid metabolism YP_001226534.1 Coenzyme metabolism YP_001226535.1 Cell envelope biogenesis, outer membrane YP_001226536.1 Carbohydrate transport and metabolism YP_001226537.1 Translation, ribosomal structure and biogenesis YP_001226539.1 Posttranslational modification, protein turnover, chaperones YP_001226540.1 Cell envelope biogenesis, outer membrane YP_001226541.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001226542.1 Cell envelope biogenesis, outer membrane YP_001226543.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001226547.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001226548.1 Coenzyme metabolism YP_001226549.1 Coenzyme metabolism YP_001226556.1 Translation, ribosomal structure and biogenesis YP_001226557.1 Missing in Prochlorococcus and in Synechococcus of the MC-A cluster; Photosynthesis YP_001226559.1 Coenzyme metabolism YP_001226560.1 stabilizes and protects the oxygen-evolving complex of photosystem II against heat-induced inactivation YP_001226562.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001226564.1 Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion YP_001226567.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001226569.1 Low identity with RCC0079; DNA replication, recombination, and repair YP_001226571.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001226581.1 Cu-Zn; Inorganic ion transport and metabolism YP_001226590.1 DNA replication, recombination, and repair YP_001226593.1 Cell division and chromosome partitioning YP_001226595.1 Posttranslational modification, protein turnover, chaperones YP_001226596.1 Cell envelope biogenesis, outer membrane YP_001226597.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001226599.1 Photosynthesis YP_001226605.1 Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only YP_001226606.1 Posttranslational modification, protein turnover, chaperones YP_001226608.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001226611.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001226612.1 Amino acid transport and metabolism YP_001226613.1 catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate YP_001226614.1 Coenzyme metabolism YP_001226615.1 Coenzyme metabolism YP_001226616.1 Coenzyme metabolism YP_001226623.1 DNA replication, recombination, and repair YP_001226624.1 DNA replication, recombination, and repair YP_001226631.1 Posttranslational modification, protein turnover, chaperones YP_001226641.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001226642.1 Posttranslational modification, protein turnover, chaperones YP_001226643.1 Cell envelope biogenesis, outer membrane YP_001226644.1 General function prediction only YP_001226645.1 Energy production and conversion YP_001226646.1 Amino acid transport and metabolism / Coenzyme metabolism YP_001226647.1 Transcription YP_001226648.1 Posttranslational modification, protein turnover, chaperones YP_001226652.1 DNA replication, recombination, and repair YP_001226653.1 Cell envelope biogenesis, outer membrane YP_001226654.1 Cell envelope biogenesis, outer membrane YP_001226655.1 Defense mechanisms YP_001226658.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001226664.1 Inorganic ion transport and metabolism YP_001226665.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001226666.1 Lipid metabolism YP_001226668.1 Carbohydrate transport and metabolism YP_001226669.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001226671.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001226672.1 Transcription YP_001226673.1 Ycf8; may be involved in the formation and/or stabilization of PSII system complexes YP_001226674.1 Photosynthesis YP_001226676.1 Photosynthesis YP_001226679.1 DNA replication, recombination, and repair / Intracellular trafficking and secretion YP_001226680.1 Coenzyme metabolism YP_001226682.1 Inorganic ion transport and metabolism YP_001226684.1 Carbohydrate transport and metabolism YP_001226685.1 Transcription YP_001226687.1 Transcription YP_001226692.1 Cell division and chromosome partitioning YP_001226693.1 Cell division and chromosome partitioning YP_001226694.1 Lipid metabolism YP_001226695.1 Possible HGT; Inorganic ion transport and metabolism YP_001226696.1 Possible HGT; Inorganic ion transport and metabolism YP_001226697.1 Cell division and chromosome partitioning YP_001226700.1 Cell envelope biogenesis, outer membrane YP_001226701.1 electron transport protein YP_001226702.1 PetD, with cytochrome b6, cytochrome F, and the Rieske protein, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001226703.1 Carbohydrate transport and metabolism YP_001226704.1 Energy production and conversion YP_001226705.1 Carbohydrate transport and metabolism YP_001226706.1 DNA replication, recombination, and repair YP_001226707.1 Stabilizes the interaction between PsaC and the photosystem I core YP_001226709.1 DNA replication, recombination, and repair YP_001226711.1 Energy production and conversion YP_001226712.1 Amino acid transport and metabolism YP_001226713.1 Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis YP_001226715.1 Amino acid transport and metabolism YP_001226716.1 Coenzyme metabolism YP_001226718.1 Translation, ribosomal structure and biogenesis YP_001226722.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001226723.1 Inorganic ion transport and metabolism YP_001226727.1 Amino acid transport and metabolism YP_001226734.1 Carbohydrate transport and metabolism YP_001226735.1 Carbohydrate transport and metabolism YP_001226737.1 DNA replication, recombination, and repair YP_001226738.1 Coenzyme metabolism YP_001226779.1 Carbohydrate transport and metabolism YP_001226780.1 DNA replication, recombination, and repair YP_001226798.1 Inorganic ion transport and metabolism YP_001226799.1 Translation, ribosomal structure and biogenesis YP_001226800.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001226801.1 Translation, ribosomal structure and biogenesis YP_001226802.1 Cell envelope biogenesis, outer membrane YP_001226803.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001226805.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001226806.1 Inorganic ion transport and metabolism YP_001226807.1 Energy production and conversion YP_001226808.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001226819.1 Signal transduction mechanisms / Transcription YP_001226821.1 Signal transduction mechanisms YP_001226822.1 Signal transduction mechanisms YP_001226825.1 Amino acid transport and metabolism YP_001226826.1 Cell envelope biogenesis, outer membrane YP_001226828.1 Translation, ribosomal structure and biogenesis YP_001226829.1 DNA replication, recombination, and repair YP_001226830.1 Translation, ribosomal structure and biogenesis YP_001226832.1 Cell envelope biogenesis, outer membrane YP_001226833.1 Photosynthesis YP_001226835.1 Amino acid transport and metabolism YP_001226837.1 Coenzyme metabolism YP_001226838.1 Cell envelope biogenesis, outer membrane YP_001226839.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001226841.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001226847.1 Cell envelope biogenesis, outer membrane YP_001226848.1 Cell envelope biogenesis, outer membrane YP_001226849.1 Coenzyme metabolism YP_001226850.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001226851.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001226852.1 ClpR variant present in an operon with ClpP3 in Synechococcus PCC7942; ClpR is missing the catalytic triad Ser-His-Asp characteristic of serine-type proteases; the exact function of ClpR and ClpP3 is unknown however they appear to be necessary for cell viability; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001226854.1 Coenzyme metabolism YP_001226855.1 Coenzyme metabolism YP_001226856.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001226857.1 Cell division and chromosome partitioning YP_001226859.1 Cell envelope biogenesis, outer membrane YP_001226860.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001226861.1 Cell envelope biogenesis, outer membrane YP_001226866.1 Coenzyme metabolism YP_001226867.1 Amino acid transport and metabolism / Coenzyme metabolism YP_001226868.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001226870.1 Translation, ribosomal structure and biogenesis YP_001226871.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001226872.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001226873.1 Possible HGT YP_001226874.1 Possible HGT YP_001226875.1 Possible HGT YP_001226877.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001226880.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001226881.1 Amino acid transport and metabolism YP_001226882.1 Possible HGT YP_001226883.1 Transcription / DNA replication, recombination, and repair YP_001226886.1 Transcription YP_001226893.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001226895.1 Transcription YP_001226896.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001226899.1 Amino acid transport and metabolism YP_001226900.1 Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion YP_001226902.1 Cell envelope biogenesis, outer membrane YP_001226904.1 Lacks the UDP-Glycosyltransferase found in ORF1916; Cell envelope biogenesis, outer membrane YP_001226905.1 Carbohydrate transport and metabolism YP_001226910.1 Amino acid transport and metabolism YP_001226912.1 Coenzyme metabolism YP_001226914.1 Defense mechanisms YP_001226915.1 transfers electrons from NAD(P)H to quinons in the respiratory chain YP_001226916.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001226917.1 Contains a Proline-rich region YP_001226923.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001226926.1 Energy production and conversion YP_001226927.1 Energy production and conversion YP_001226928.1 Energy production and conversion YP_001226930.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001226931.1 Defense mechanisms YP_001226932.1 Defense mechanisms YP_001226934.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001226937.1 Lipid metabolism YP_001226938.1 Inorganic ion transport and metabolism YP_001226940.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001226942.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001226943.1 Nucleotide transport and metabolism / Inorganic ion transport and metabolism YP_001226952.1 RepA is a 5'-3' DNA helicase which can utilize ATP, GTP and CTP, Strong similarity of the N-terminus with PMT0921 YP_001226955.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001226956.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001226957.1 Coenzyme metabolism YP_001226958.1 Cell envelope biogenesis, outer membrane YP_001226959.1 cytochrome f, with cytochrome b6, subunit IV, and the Rieske protein, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001226960.1 Rieske protein, with cytochrome b6, cytochrome f, and subunit IV, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001226962.1 Intracellular trafficking and secretion YP_001226964.1 Essential for recycling GMP and indirectly, cGMP YP_001226965.1 Enables the organization of the psaE and psaF subunits YP_001226966.1 Photosynthesis YP_001226970.1 Cell envelope biogenesis, outer membrane YP_001226972.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001226976.1 Amino acid transport and metabolism YP_001226977.1 Amino acid transport and metabolism YP_001226979.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001226983.1 Coenzyme metabolism YP_001226984.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001226985.1 Photosynthesis YP_001226987.1 Defense mechanisms YP_001226988.1 Translation, ribosomal structure and biogenesis YP_001226990.1 cytochrome b6-f complex subunit 5; plastohydroquinone/plastocyanin oxidoreductase; with PetL, PetM and PetN makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001226991.1 DNA replication, recombination, and repair YP_001226992.1 Amino acid transport and metabolism YP_001226995.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001226998.1 negatively supercoils closed circular double-stranded DNA YP_001226999.1 Lipid metabolism YP_001227002.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001227003.1 Carbohydrate transport and metabolism YP_001227005.1 Coenzyme metabolism YP_001227007.1 Lipid metabolism YP_001227009.1 Related to viral helicase ? YP_001227011.1 Carbohydrate transport and metabolism YP_001227012.1 catalyzes the hydrolysis of acylphosphate YP_001227013.1 Coenzyme metabolism YP_001227014.1 Carbohydrate transport and metabolism YP_001227015.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001227016.1 Photosynthesis YP_001227018.1 interacts with the circadian clock regulator KaiC to maintain circadian rhythms YP_001227023.1 Amino acid transport and metabolism YP_001227027.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001227030.1 Energy production and conversion YP_001227031.1 amylomaltase; acts to release glucose from maltodextrins YP_001227033.1 Translation, ribosomal structure and biogenesis YP_001227034.1 Signal transduction mechanisms YP_001227035.1 Signal transduction mechanisms YP_001227038.1 Amino acid transport and metabolism YP_001227039.1 catalyzes the formation of precorrin-8x from precorrin-6y YP_001227040.1 Lipid metabolism YP_001227043.1 Energy production and conversion YP_001227044.1 Posttranslational modification, protein turnover, chaperones YP_001227046.1 Amino acid transport and metabolism YP_001227048.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001227049.1 Coenzyme metabolism YP_001227051.1 Amino acid transport and metabolism YP_001227052.1 Amino acid transport and metabolism YP_001227053.1 Fused with a domain of Unknown function YP_001227056.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001227057.1 DNA replication, recombination, and repair YP_001227058.1 Photosynthesis YP_001227075.1 type III RuBisCO; involved in carbon fixation YP_001227076.1 Carbohydrate transport and metabolism YP_001227082.1 Inorganic ion transport and metabolism YP_001227083.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001227084.1 Energy production and conversion YP_001227085.1 Inorganic ion transport and metabolism YP_001227087.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001227088.1 Posttranslational modification, protein turnover, chaperones YP_001227094.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001227095.1 Energy production and conversion YP_001227096.1 Translation, ribosomal structure and biogenesis YP_001227109.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001227110.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001227111.1 DNA replication, recombination, and repair YP_001227113.1 Coenzyme metabolism YP_001227115.1 Catalyzes the phosphorylation of UMP to UDP YP_001227116.1 Translation, ribosomal structure and biogenesis YP_001227119.1 maintains the balance of metabolites in the pentose-phosphate pathway YP_001227120.1 Cell envelope biogenesis, outer membrane YP_001227123.1 Carbohydrate transport and metabolism YP_001227124.1 Nucleotide transport and metabolism YP_001227125.1 Intracellular trafficking and secretion YP_001227129.1 Energy production and conversion YP_001227132.1 Translation, ribosomal structure and biogenesis YP_001227134.1 Photosynthesis YP_001227135.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001227136.1 Carbohydrate transport and metabolism YP_001227137.1 Inorganic ion transport and metabolism YP_001227138.1 Coenzyme metabolism YP_001227139.1 DNA replication, recombination, and repair YP_001227142.1 Amino acid transport and metabolism YP_001227144.1 DNA replication, recombination, and repair YP_001227145.1 Transcription YP_001227148.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001227152.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001227153.1 Amino acid transport and metabolism YP_001227154.1 Lipid metabolism YP_001227156.1 Coenzyme metabolism YP_001227157.1 Signal transduction mechanisms YP_001227158.1 Carbohydrate transport and metabolism YP_001227162.1 Posttranslational modification, protein turnover, chaperones YP_001227165.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001227169.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001227171.1 Possible secreted protein, possibly specific to RCC307 (compositional bias, mask the G residues in protein sequence before blast search) YP_001227173.1 Photosynthesis YP_001227174.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001227175.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001227176.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001227182.1 Amino acid transport and metabolism YP_001227183.1 Coenzyme metabolism YP_001227197.1 Amino acid transport and metabolism YP_001227198.1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunit D, with NdhB and NdhF are core membrane components YP_001227199.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001227200.1 Carbohydrate transport and metabolism YP_001227201.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001227207.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001227210.1 Nucleotide transport and metabolism YP_001227214.1 Signal transduction mechanisms YP_001227215.1 Signal transduction mechanisms YP_001227217.1 Possible HGT; Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis YP_001227222.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001227224.1 Coenzyme metabolism YP_001227226.1 catalyzes the formation of Mg-protoporphyrin IX from protoporphyrin IX and Mg(2+); first committed step of chlorophyll biosynthesis YP_001227227.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001227229.1 Coenzyme metabolism YP_001227230.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001227234.1 Amino acid transport and metabolism YP_001227236.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001227240.1 Amino acid transport and metabolism YP_001227246.1 Coenzyme metabolism YP_001227249.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001227250.1 Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion YP_001227252.1 Energy production and conversion YP_001227253.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001227254.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001227255.1 Amino acid transport and metabolism YP_001227258.1 DNA replication, recombination, and repair YP_001227265.1 Inorganic ion transport and metabolism YP_001227266.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001227268.1 Lipid metabolism YP_001227274.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001227279.1 Inorganic ion transport and metabolism YP_001227280.1 Possible frameshift with RCC1029 YP_001227281.1 Possible frameshift with RCC1028 YP_001227282.1 Nucleotide transport and metabolism YP_001227288.1 Possible pseudogene YP_001227301.1 DNA replication, recombination, and repair YP_001227302.1 Homologous to sll0033 See Masamoto et al., 2001 Plant Cell Physiol 42:1398-1402 YP_001227306.1 Inorganic ion transport and metabolism YP_001227317.1 Coenzyme metabolism YP_001227335.1 General function prediction only YP_001227362.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001227365.1 Transcription YP_001227371.1 Cell motility and secretion YP_001227373.1 Energy production and conversion YP_001227376.1 Signal transduction mechanisms YP_001227379.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001227380.1 Amino acid transport and metabolism YP_001227381.1 Nucleotide transport and metabolism YP_001227383.1 Inorganic ion transport and metabolism YP_001227384.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001227390.1 Inorganic ion transport and metabolism YP_001227392.1 Carbohydrate transport and metabolism YP_001227395.1 Intracellular trafficking and secretion YP_001227396.1 Coenzyme metabolism YP_001227397.1 Coenzyme metabolism YP_001227400.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001227402.1 Cell envelope biogenesis, outer membrane YP_001227404.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001227406.1 Amino acid transport and metabolism YP_001227409.1 Transcription YP_001227410.1 Coenzyme metabolism YP_001227411.1 Coenzyme metabolism / General function prediction only YP_001227413.1 Cell envelope biogenesis, outer membrane YP_001227414.1 Cell envelope biogenesis, outer membrane YP_001227415.1 Lipid metabolism YP_001227420.1 DNA replication, recombination, and repair YP_001227421.1 DNA replication, recombination, and repair YP_001227425.1 Carbohydrate transport and metabolism YP_001227432.1 Possible HGT, weak similarity with N-terminal part of putative xylanase YP_001227435.1 Inorganic ion transport and metabolism YP_001227441.1 DNA replication, recombination, and repair YP_001227444.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001227446.1 Amino acid transport and metabolism YP_001227447.1 Amino acid transport and metabolism YP_001227450.1 Cell envelope biogenesis, outer membrane YP_001227452.1 Coenzyme metabolism YP_001227453.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001227457.1 Signal transduction mechanisms YP_001227458.1 Energy production and conversion YP_001227463.1 Coenzyme metabolism YP_001227464.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001227465.1 Amino acid transport and metabolism YP_001227470.1 NAD(P)+; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001227473.1 Nucleotide transport and metabolism YP_001227477.1 Photosynthesis YP_001227479.1 Translation, ribosomal structure and biogenesis YP_001227480.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001227481.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001227482.1 Transcription YP_001227484.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001227489.1 involved in light-induced Na+-dependent proton extrusion YP_001227490.1 Coenzyme metabolism YP_001227491.1 Translation, ribosomal structure and biogenesis YP_001227494.1 Posttranslational modification, protein turnover, chaperones YP_001227496.1 Nucleotide transport and metabolism YP_001227497.1 Nucleotide transport and metabolism YP_001227502.1 Nucleotide transport and metabolism YP_001227504.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001227507.1 Carbohydrate transport and metabolism YP_001227508.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001227509.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001227510.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001227511.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001227512.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001227513.1 Strong similarity with N-terminal part of 60 kDa chaperonin GroEL YP_001227522.1 Cell envelope biogenesis, outer membrane YP_001227523.1 Photosynthesis YP_001227524.1 Translation, ribosomal structure and biogenesis YP_001227525.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001227526.1 Cell envelope biogenesis, outer membrane YP_001227527.1 catalyzes branch migration in Holliday junction intermediates YP_001227529.1 Translation, ribosomal structure and biogenesis YP_001227530.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001227537.1 Export of glycolopid, see Fiedler et al, 1998, Mol. Microbiol, 27(6):1193-202 YP_001227538.1 Export of glycolopid, see Fiedler et al, 1998, Mol. Microbiol, 27(6):1193-202 YP_001227539.1 Export of glycolopid, see Fiedler et al, 1998, Mol. Microbiol, 27(6):1193-202 YP_001227540.1 catalyzes the reduction of biliverdin IX-alpha producing (3Z)-phycocyanobilin and oxidized ferredoxin YP_001227545.1 Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion YP_001227546.1 Cell envelope biogenesis, outer membrane YP_001227549.1 Translation, ribosomal structure and biogenesis YP_001227550.1 Amino acid transport and metabolism YP_001227551.1 Photosynthesis YP_001227552.1 Amino acid transport and metabolism YP_001227557.1 Signal transduction mechanisms YP_001227560.1 PsbW; part of the phosystem II reaction center YP_001227566.1 Intracellular trafficking and secretion YP_001227567.1 Intracellular trafficking and secretion YP_001227568.1 Energy production and conversion YP_001227570.1 Lipid metabolism YP_001227571.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001227572.1 DNA replication, recombination, and repair YP_001227575.1 synthesizes RNA primers at the replication forks YP_001227578.1 DNA replication, recombination, and repair YP_001227579.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001227581.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001227582.1 Translation, ribosomal structure and biogenesis YP_001227584.1 Translation, ribosomal structure and biogenesis YP_001227586.1 Signal transduction mechanisms YP_001227587.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001227588.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001227592.1 Posttranslational modification, protein turnover, chaperones YP_001227595.1 Photosynthesis YP_001227597.1 DNA replication, recombination, and repair YP_001227598.1 Posttranslational modification, protein turnover, chaperones YP_001227600.1 Inorganic ion transport and metabolism YP_001227601.1 Lipid metabolism YP_001227603.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001227608.1 Nucleotide transport and metabolism YP_001227609.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001227610.1 Coenzyme metabolism YP_001227611.1 Posttranslational modification, protein turnover, chaperones YP_001227612.1 Nucleotide transport and metabolism YP_001227613.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001227615.1 Posttranslational modification, protein turnover, chaperones YP_001227616.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001227617.1 Inorganic ion transport and metabolism YP_001227618.1 Inorganic ion transport and metabolism YP_001227619.1 Inorganic ion transport and metabolism YP_001227620.1 Inorganic ion transport and metabolism YP_001227621.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001227622.1 Why sphX and not pstS ? Ask Martin; Inorganic ion transport and metabolism YP_001227624.1 Carbohydrate transport and metabolism YP_001227625.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001227627.1 molecular chaperone YP_001227628.1 Cell envelope biogenesis, outer membrane YP_001227629.1 Carbohydrate transport and metabolism YP_001227630.1 Carbohydrate transport and metabolism YP_001227631.1 Carbohydrate transport and metabolism YP_001227632.1 Carbohydrate transport and metabolism YP_001227633.1 Carbohydrate transport and metabolism YP_001227636.1 Carbohydrate transport and metabolism YP_001227637.1 Energy production and conversion YP_001227638.1 Energy production and conversion YP_001227639.1 Translation, ribosomal structure and biogenesis YP_001227640.1 Posttranslational modification, protein turnover, chaperones YP_001227644.1 photosystem I subunit PsaK; maybe involved in the assembly of PSI monomers into trimers; active under low light conditions YP_001227646.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001227647.1 Amino acid transport and metabolism YP_001227648.1 Transcription YP_001227649.1 Photosynthesis YP_001227655.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001227656.1 Defense mechanisms YP_001227657.1 Very low identity with RCC0226; DNA replication, recombination, and repair YP_001227658.1 Cell division and chromosome partitioning YP_001227660.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; in Synechococcus this protein (ClpP1)is constitutive and levels increased with the increase of light. YP_001227661.1 Psb29; involved in biogenesis of the photosystem II; in Arabidopsis it interacts with the heterotrimeric G-protein (GPA1) and seems to be involved in a D-glucose signaling mechanism between plastid and the plasma membranes YP_001227663.1 subunit VIII; plays a crucial role in complex assembly and/or stability; with PetL, PetG and PetM makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001227664.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001227673.1 Nucleotide transport and metabolism YP_001227674.1 Carbohydrate transport and metabolism YP_001227675.1 Amino acid transport and metabolism YP_001227678.1 Possible HGT YP_001227681.1 Carbohydrate transport and metabolism YP_001227684.1 DNA replication, recombination, and repair YP_001227686.1 Coenzyme metabolism YP_001227687.1 Translation, ribosomal structure and biogenesis YP_001227689.1 Signal transduction mechanisms YP_001227690.1 Inorganic ion transport and metabolism YP_001227692.1 Defense mechanisms YP_001227694.1 Inorganic ion transport and metabolism YP_001227696.1 Photosynthesis YP_001227697.1 Photosynthesis YP_001227701.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001227702.1 Carbohydrate transport and metabolism YP_001227703.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001227704.1 Cobalt import; Inorganic ion transport and metabolism YP_001227710.1 Transcription YP_001227711.1 Inorganic ion transport and metabolism YP_001227712.1 Inorganic ion transport and metabolism YP_001227713.1 Weak similarity with RCC2424; Inorganic ion transport and metabolism YP_001227714.1 Amino acid transport and metabolism YP_001227716.1 DNA replication, recombination, and repair YP_001227718.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001227719.1 Cell envelope biogenesis, outer membrane YP_001227721.1 DNA replication, recombination, and repair / Transcription YP_001227727.1 Inorganic ion transport and metabolism YP_001227729.1 Amino acid transport and metabolism YP_001227732.1 oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis YP_001227736.1 Transcription YP_001227740.1 Inorganic ion transport and metabolism YP_001227741.1 DNA replication, recombination, and repair YP_001227742.1 Inorganic ion transport and metabolism YP_001227744.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001227745.1 Cell division and chromosome partitioning YP_001227747.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001227749.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001227751.1 Posttranslational modification, protein turnover, chaperones YP_001227753.1 Posttranslational modification, protein turnover, chaperones YP_001227754.1 Possible HGT YP_001227760.1 Coenzyme metabolism YP_001227761.1 Possible HGT YP_001227764.1 Homologous to por gene RCC1578. Need to correct annotation of ORF0873 (paralog of ORF2487) YP_001227795.1 Inorganic ion transport and metabolism YP_001227796.1 component of photosystem II; manganese-binding polypeptide with arginine metablolizing activity YP_001227797.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001227798.1 Homologous to sll0033 See Masamoto et al., 2001 Plant Cell Physiol 42:1398-1402 YP_001227800.1 Amino acid transport and metabolism YP_001227802.1 Signal transduction mechanisms YP_001227805.1 Posttranslational modification, protein turnover, chaperones YP_001227808.1 Lipid metabolism YP_001227809.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001227811.1 DNA replication, recombination, and repair YP_001227812.1 DNA replication, recombination, and repair YP_001227813.1 DNA replication, recombination, and repair YP_001227815.1 Carbohydrate transport and metabolism YP_001227816.1 DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis YP_001227820.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001227821.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001227822.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production YP_001227826.1 Inorganic ion transport and metabolism YP_001227827.1 Inorganic ion transport and metabolism YP_001227828.1 Converts chlorophyllide a into protochlorophyllide; light dependent YP_001227830.1 Photosynthesis YP_001227831.1 Inorganic ion transport and metabolism YP_001227834.1 Coenzyme metabolism YP_001227836.1 Amino acid transport and metabolism YP_001227838.1 Coenzyme metabolism YP_001227840.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001227843.1 Amino acid transport and metabolism YP_001227844.1 Translation, ribosomal structure and biogenesis YP_001227853.1 Lipid metabolism YP_001227854.1 Photosynthesis YP_001227855.1 unknown function; YciI from Haemophilus influenzae has a crystal structure similar to a muconolactone isomerase, but does not seem to catalyze any of the reactions predicted from the sequence or structure similarity YP_001227856.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001227865.1 Transcription YP_001227868.1 Inorganic ion transport and metabolism YP_001227869.1 Inorganic ion transport and metabolism YP_001227870.1 Inorganic ion transport and metabolism YP_001227872.1 Putative frameshift with RCC1623 YP_001227873.1 Similar to C-terminus of ORF0999 and SYNW0974; Putative frameshift with RCC1622 YP_001227875.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001227876.1 Coenzyme metabolism YP_001227877.1 Inorganic ion transport and metabolism YP_001227883.1 Transcription YP_001227885.1 Inorganic ion transport and metabolism YP_001227889.1 Inorganic ion transport and metabolism YP_001227890.1 Inorganic ion transport and metabolism YP_001227891.1 Inorganic ion transport and metabolism YP_001227892.1 Inorganic ion transport and metabolism YP_001227893.1 Inorganic ion transport and metabolism YP_001227902.1 DNA replication, recombination, and repair YP_001227903.1 Energy production and conversion YP_001227904.1 Coenzyme metabolism YP_001227905.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001227906.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001227907.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001227908.1 Amino acid transport and metabolism YP_001227913.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001227918.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_001227920.1 Translation, ribosomal structure and biogenesis YP_001227922.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001227923.1 Inorganic ion transport and metabolism YP_001227925.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001227926.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001227930.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001227939.1 Posttranslational modification, protein turnover, chaperones YP_001227940.1 Translation, ribosomal structure and biogenesis YP_001227942.1 Translation, ribosomal structure and biogenesis YP_001227944.1 Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism YP_001227945.1 Ycf31; cytochrome b6-f complex subunit 7; with PetL, PetG and PetN makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001227946.1 Translation, ribosomal structure and biogenesis YP_001227948.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001227949.1 Posttranslational modification, protein turnover, chaperones YP_001227950.1 required for the assembly of photosystem I complex YP_001227951.1 Photosynthesis YP_001227952.1 Photosynthesis YP_001227953.1 Cell division and chromosome partitioning YP_001227955.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001227958.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001227960.1 Transcription YP_001227962.1 Energy production and conversion YP_001227964.1 Intracellular trafficking and secretion YP_001227965.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001227966.1 Signal transduction mechanisms YP_001227969.1 Defense mechanisms YP_001227972.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001227978.1 Strong similarity with the C-terminus of RCC1726 YP_001227981.1 Secreted protein, possible HGT YP_001227983.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001227986.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001227992.1 Coenzyme metabolism YP_001227993.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001227994.1 Coenzyme metabolism YP_001227996.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001227997.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001227999.1 catalyzes the phosphorylation of NAD to NADP YP_001228000.1 Signal transduction mechanisms YP_001228002.1 Coenzyme metabolism YP_001228004.1 Frameshift with RCC1755 YP_001228005.1 Frameshift with RCC1754 YP_001228007.1 Coenzyme metabolism YP_001228010.1 Cell division and chromosome partitioning YP_001228011.1 Amino acid transport and metabolism YP_001228012.1 Transcription / Signal transduction mechanisms YP_001228013.1 Lipid metabolism YP_001228043.1 Cell envelope biogenesis, outer membrane YP_001228044.1 Signal transduction mechanisms YP_001228046.1 Posttranslational modification, protein turnover, chaperones YP_001228047.1 Fe; Inorganic ion transport and metabolism YP_001228048.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001228049.1 Amino acid transport and metabolism YP_001228050.1 Energy production and conversion YP_001228052.1 Lipid metabolism YP_001228053.1 Coenzyme metabolism YP_001228055.1 Nucleotide transport and metabolism YP_001228056.1 DNA replication, recombination, and repair YP_001228059.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001228060.1 Sugar phosphate isomerase YP_001228061.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001228065.1 Amino acid transport and metabolism YP_001228067.1 Transcription YP_001228070.1 Posttranslational modification, protein turnover, chaperones YP_001228071.1 CAZy:GT19; catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001228072.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001228073.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001228074.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001228075.1 Cell envelope biogenesis, outer membrane YP_001228076.1 Nucleotide transport and metabolism YP_001228078.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001228079.1 Signal transduction mechanisms YP_001228080.1 acts as a promotor non-specific transcription repressor YP_001228081.1 Decreases the phosphorylation of KaiC, a component of the main circadian regulator in cyanobacteria YP_001228083.1 Translation, ribosomal structure and biogenesis YP_001228084.1 involved in the peptidyltransferase reaction during translation YP_001228087.1 Translation, ribosomal structure and biogenesis YP_001228088.1 Possible HGT YP_001228092.1 Amino acid transport and metabolism YP_001228093.1 Carbohydrate transport and metabolism YP_001228096.1 low-potential cytochrome c; with PsbO, PsbP, PsbQ, and PsbU makes up the oxygen-evolving complex of photosystem II YP_001228098.1 Photosynthesis YP_001228099.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001228100.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001228103.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001228107.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001228109.1 Posttranslational modification, protein turnover, chaperones YP_001228111.1 Energy production and conversion YP_001228112.1 Nucleotide transport and metabolism YP_001228113.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001228114.1 Intracellular trafficking and secretion YP_001228115.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001228116.1 Posttranslational modification, protein turnover, chaperones YP_001228117.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001228118.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001228119.1 Translation, ribosomal structure and biogenesis YP_001228121.1 Inorganic ion transport and metabolism YP_001228122.1 Amino acid transport and metabolism YP_001228125.1 Coenzyme metabolism YP_001228126.1 Coenzyme metabolism YP_001228127.1 Amino acid transport and metabolism YP_001228133.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001228134.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001228135.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001228136.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_001228137.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001228138.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001228139.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001228140.1 Energy production and conversion YP_001228142.1 Photosynthesis YP_001228143.1 Photosynthesis YP_001228144.1 Photosynthesis YP_001228145.1 Photosynthesis YP_001228146.1 Cell division and chromosome partitioning YP_001228148.1 Posttranslational modification, protein turnover, chaperones YP_001228149.1 Posttranslational modification, protein turnover, chaperones YP_001228151.1 Amino acid transport and metabolism YP_001228155.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001228167.1 Coenzyme metabolism YP_001228178.1 Carbohydrate transport and metabolism YP_001228179.1 DNA replication, recombination, and repair YP_001228180.1 Coenzyme metabolism YP_001228183.1 Coenzyme metabolism YP_001228184.1 Carbohydrate transport and metabolism YP_001228187.1 Amino acid transport and metabolism YP_001228189.1 Amino acid transport and metabolism YP_001228190.1 Energy production and conversion YP_001228191.1 Energy production and conversion YP_001228193.1 Energy production and conversion YP_001228196.1 Energy production and conversion YP_001228197.1 Coenzyme metabolism YP_001228202.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001228210.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001228212.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001228213.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001228214.1 Strong similarity with the C-terminus of RpoB (RCC1967) YP_001228215.1 Transcription YP_001228216.1 DNA replication, recombination, and repair YP_001228217.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001228218.1 Amino acid transport and metabolism YP_001228220.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001228221.1 Posttranslational modification, protein turnover, chaperones YP_001228224.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001228225.1 Transcription YP_001228226.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001228244.1 Energy production and conversion YP_001228258.1 Carbohydrate transport and metabolism YP_001228259.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001228265.1 Photosynthesis YP_001228266.1 Carbohydrate transport and metabolism YP_001228268.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001228269.1 Amino acid transport and metabolism YP_001228271.1 Amino acid transport and metabolism YP_001228274.1 with SufCD activates cysteine desulfurase SufS YP_001228276.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001228277.1 Transcription YP_001228280.1 Shows some homology to CpeS and WH8020 / ORF200 YP_001228281.1 Photosynthesis YP_001228284.1 long gap in N-term region compared to WH8102; Photosynthesis YP_001228285.1 amidophosphoribosyltransferase domain YP_001228290.1 Orthologs in other marine Synechococcus spp. also located in phycobilisome rod gene region YP_001228291.1 Possible photoresponsive regulatory phycobiliprotein; orthologs in other marine Synechococcus spp. also located in phycobilisome rod gene region YP_001228292.1 Photosynthesis YP_001228293.1 Orthologs in other marine Synechococcus spp. also located in phycobilisome rod gene region YP_001228294.1 Photosynthesis YP_001228295.1 Photosynthesis YP_001228296.1 Photosynthesis YP_001228297.1 CpeT homolog, phycoerythrin linker gene region YP_001228298.1 CpeS homolog, phycoerythrin linker gene region YP_001228299.1 Signal transduction mechanisms YP_001228300.1 Orthologs in other marine Synechococcus spp. sometimes also located in phycobilisome rod gene region YP_001228301.1 Orthologs in some other marine Synechococcus spp. YP_001228303.1 CpeY homolog; Photosynthesis YP_001228304.1 Photosynthesis YP_001228305.1 Photosynthesis YP_001228306.1 incorrect C-term; Photosynthesis YP_001228307.1 Photosynthesis YP_001228308.1 Photosynthesis YP_001228309.1 Photosynthesis YP_001228310.1 possible ortholog in CC9902 YP_001228311.1 Orthologs in other marine Synechococcus spp. also located in phycobilisome rod gene region YP_001228312.1 Photosynthesis YP_001228313.1 Photosynthesis YP_001228314.1 Photosynthesis YP_001228315.1 N-term likely 35-aa too long; Orthologs in other marine Synechococcus WH7803 and Prochlorococcus SS120 and MIT9313 located at similar position in phycobilisome rod gene region YP_001228316.1 Orthologs in other marine Synechococcus spp. also located in phycobilisome rod gene region YP_001228317.1 catalyzes the reduction of biliverdin IX-alpha to 15,16-dihydrobiliverdin YP_001228318.1 catalyzes the reduction of 15,16-dihydrobiliverdin to (3Z)-phycoerythrobilin YP_001228319.1 Photosynthesis YP_001228320.1 Photosynthesis YP_001228321.1 Ortholog in RS9917 YP_001228322.1 Photosynthesis YP_001228323.1 Photosynthesis YP_001228324.1 Signal transduction mechanisms YP_001228325.1 catalyzes the formation of pantothenate from pantoate and beta-alanine and the formation of cytidine diphosphate from cytidine monophosphate YP_001228326.1 Cell envelope biogenesis, outer membrane YP_001228327.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001228335.1 Transcription YP_001228339.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001228340.1 Cell division and chromosome partitioning YP_001228341.1 Cell division and chromosome partitioning YP_001228342.1 Signal transduction mechanisms YP_001228343.1 Photosynthesis YP_001228344.1 Amino acid transport and metabolism YP_001228346.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001228348.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001228350.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001228352.1 Possible HGT YP_001228354.1 Coenzyme metabolism YP_001228357.1 Defense mechanisms YP_001228358.1 Coenzyme metabolism YP_001228362.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001228363.1 Amino acid transport and metabolism YP_001228364.1 DNA replication, recombination, and repair YP_001228367.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001228372.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001228373.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001228374.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001228375.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001228376.1 Translation, ribosomal structure and biogenesis YP_001228377.1 Translation, ribosomal structure and biogenesis YP_001228378.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001228379.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001228380.1 Translation, ribosomal structure and biogenesis YP_001228381.1 Translation, ribosomal structure and biogenesis YP_001228382.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001228383.1 Translation, ribosomal structure and biogenesis YP_001228384.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001228385.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001228386.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001228387.1 Translation, ribosomal structure and biogenesis YP_001228388.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001228389.1 Translation, ribosomal structure and biogenesis YP_001228390.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001228391.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001228392.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001228393.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001228394.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001228395.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001228396.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001228397.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001228398.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001228399.1 forms a direct contact with the tRNA during translation YP_001228400.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001228401.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001228402.1 Defense mechanisms YP_001228403.1 Cell envelope biogenesis, outer membrane YP_001228407.1 Cell envelope biogenesis, outer membrane YP_001228409.1 Photosynthesis YP_001228410.1 Photosynthesis YP_001228411.1 Defense mechanisms YP_001228413.1 with PsaA binds the primary electron donor of photosystem I, P700, and subsequent electron acceptors as part of photosystem I YP_001228414.1 with PsaB binds the primary electron donor of photosystem I, P700, and subsequent electron acceptors as part of photosystem I YP_001228416.1 Coenzyme metabolism YP_001228417.1 Defense mechanisms YP_001228418.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001228419.1 Inorganic ion transport and metabolism YP_001228420.1 Amino acid transport and metabolism YP_001228423.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001228424.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001228425.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001228426.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001228427.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001228429.1 Lipid metabolism YP_001228430.1 Amino acid transport and metabolism YP_001228432.1 DNA replication, recombination, and repair YP_001228433.1 Translation, ribosomal structure and biogenesis YP_001228435.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis YP_001228436.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001228439.1 Photosynthesis YP_001228440.1 Possible HGT YP_001228442.1 See Bartsevich and Pakrasi EMBO Journal 1995 14(9):1845-53; Inorganic ion transport and metabolism YP_001228443.1 See Bartsevich and Pakrasi EMBO Journal 1995 14(9):1845-53; Inorganic ion transport and metabolism YP_001228444.1 See Bartsevich and Pakrasi EMBO Journal 1995 14(9):1845-53; Inorganic ion transport and metabolism YP_001228445.1 Carbohydrate transport and metabolism YP_001228446.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001228448.1 Carbohydrate transport and metabolism YP_001228449.1 Cell division and chromosome partitioning YP_001228450.1 Inorganic ion transport and metabolism YP_001228451.1 Photosynthesis YP_001228453.1 Coenzyme metabolism YP_001228459.1 Energy production and conversion YP_001228460.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001228461.1 DNA replication, recombination, and repair YP_001228464.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001228465.1 Lipid metabolism YP_001228468.1 Translation, ribosomal structure and biogenesis YP_001228472.1 Translation, ribosomal structure and biogenesis YP_001228473.1 Inorganic ion transport and metabolism YP_001228474.1 Carbohydrate transport and metabolism YP_001228475.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001228477.1 Cell envelope biogenesis, outer membrane YP_001228481.1 CAZy:GT28; Cell envelope biogenesis, outer membrane YP_001228485.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001228487.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001228488.1 Translation, ribosomal structure and biogenesis YP_001228489.1 Carbohydrate transport and metabolism YP_001228490.1 Amino acid transport and metabolism YP_001228491.1 Signal transduction mechanisms YP_001228492.1 Inorganic ion transport and metabolism YP_001228494.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001228496.1 Coenzyme metabolism YP_001228497.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001228498.1 Amino acid transport and metabolism YP_001228500.1 Coenzyme metabolism YP_001228501.1 Cell envelope biogenesis, outer membrane YP_001228504.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001228506.1 Posttranslational modification, protein turnover, chaperones YP_001228507.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001228508.1 Coenzyme metabolism YP_001228509.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate YP_001228510.1 Coenzyme metabolism YP_001228511.1 Coenzyme metabolism YP_001228513.1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradien YP_001228514.1 Cell envelope biogenesis, outer membrane YP_001228515.1 Amino acid transport and metabolism YP_001228517.1 Signal transduction mechanisms YP_001228518.1 Translation, ribosomal structure and biogenesis YP_001228519.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine YP_001228520.1 Carbohydrate transport and metabolism YP_001228521.1 Nucleotide transport and metabolism YP_001228523.1 Inorganic ion transport and metabolism YP_001228524.1 Translation, ribosomal structure and biogenesis YP_001228527.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001228528.1 Transcription YP_001228531.1 Signal transduction mechanisms YP_001228532.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_001228533.1 Catalyzes the transfer of electrons from NADH to quinone YP_001228534.1 Catalyzes the transfer of electrons from NADH to quinone YP_001228535.1 Catalyzes the transfer of electrons from NADH to quinone YP_001228536.1 Catalyzes the transfer of electrons from NADH to quinone YP_001228537.1 Carbohydrate transport and metabolism YP_001228543.1 IPR006050 Cryptochrome/photolyase, N-terminal domain YP_001228545.1 NADH-dependent; catalyzes a key regulatory step in fatty acid biosynthesis YP_001228546.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001228548.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001228550.1 Amino acid transport and metabolism YP_001228551.1 Amino acid transport and metabolism YP_001228553.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001228554.1 Carbohydrate transport and metabolism YP_001228556.1 DNA replication, recombination, and repair YP_001228557.1 General function prediction only YP_001228558.1 Nucleotide transport and metabolism YP_001228560.1 Posttranslational modification, protein turnover, chaperones YP_001228562.1 Inorganic ion transport and metabolism YP_001228566.1 may be involved in binding plastoquinone and maintaining PSII dimers YP_001228567.1 Translation, ribosomal structure and biogenesis YP_001228568.1 Coenzyme metabolism YP_001228569.1 Signal transduction mechanisms YP_001228575.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001228576.1 Inorganic ion transport and metabolism YP_001228584.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001228585.1 Cell envelope biogenesis, outer membrane YP_001228587.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001228588.1 Amino acid transport and metabolism YP_001228591.1 4.8-kDa protein; may be involved in assembling and stabilizing of PSII dimers YP_001228592.1 Carbohydrate transport and metabolism YP_001228593.1 Photosynthesis YP_001228594.1 may be involved in regulating PSII assembly and/or stability YP_001228595.1 Intracellular trafficking and secretion YP_001228596.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001228600.1 Signal transduction mechanisms YP_001228601.1 Coenzyme metabolism YP_001228602.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001228603.1 Nucleotide transport and metabolism YP_001228604.1 Amino acid transport and metabolism YP_001228609.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001228610.1 DNA replication, recombination, and repair YP_001228611.1 Translation, ribosomal structure and biogenesis YP_001228612.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001228613.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001228614.1 binds directly to 23S ribosomal RNA YP_001228615.1 Modulates Rho-dependent transcription termination YP_001228616.1 Intracellular trafficking and secretion YP_001228617.1 Posttranslational modification, protein turnover, chaperones YP_001228618.1 Amino acid transport and metabolism YP_001228619.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001228625.1 Translation, ribosomal structure and biogenesis YP_001228629.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001228630.1 Coenzyme metabolism YP_001228631.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001228632.1 Amino acid transport and metabolism YP_001228633.1 Nucleotide transport and metabolism YP_001228634.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001228636.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001228637.1 Transcription / DNA replication, recombination, and repair YP_001228640.1 Posttranslational modification, protein turnover, chaperones YP_001228642.1 Energy production and conversion YP_001228643.1 Energy production and conversion YP_001228646.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001228647.1 Amino acid transport and metabolism YP_001228648.1 Inorganic ion transport and metabolism YP_001228649.1 Lipid metabolism YP_001228651.1 Lipid metabolism YP_001228652.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001228653.1 DNA replication, recombination, and repair YP_001228655.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001228665.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001228666.1 Signal transduction mechanisms YP_001228667.1 Weak similarity with RCC1463; Inorganic ion transport and metabolism YP_001228668.1 Signal transduction mechanisms YP_001228672.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001228675.1 Signal transduction mechanisms YP_001228677.1 Secondary metabolites biosynthesis, transport, and catabolism YP_001228684.1 Possible HGT YP_001228688.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001228690.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001228691.1 See Quintero et al., J. Bact. 2000 182:1008-15; Amino acid transport and metabolism YP_001228693.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001228694.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001228695.1 Transcription YP_001228698.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001228700.1 Transcription regulator related protein YP_001228701.1 Coenzyme metabolism YP_001228702.1 Amino acid transport and metabolism YP_001228706.1 Amino acid transport and metabolism YP_001228707.1 Amino acid transport and metabolism YP_001228708.1 Amino acid transport and metabolism YP_001228709.1 Amino acid transport and metabolism YP_001228710.1 Amino acid transport and metabolism YP_001228711.1 Amino acid transport and metabolism YP_001228713.1 Amino acid transport and metabolism YP_001228714.1 Amino acid transport and metabolism YP_001228715.1 Amino acid transport and metabolism YP_001228717.1 Amino acid transport and metabolism YP_001228718.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001228719.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001228723.1 Amino acid transport and metabolism YP_001228725.1 DNA replication, recombination, and repair YP_001228729.1 Inorganic ion transport and metabolism YP_001228730.1 Inorganic ion transport and metabolism YP_001228731.1 Inorganic ion transport and metabolism YP_001228734.1 See Quintero et al., J. Bact. 2000 182:1008-15; Amino acid transport and metabolism YP_001228735.1 Coenzyme metabolism YP_001228738.1 ferredoxin-dependent assimilatory nitrite reductase YP_001228739.1 Inorganic ion transport and metabolism YP_001228741.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001228742.1 Weak similarity with RCC1338 YP_001228746.1 Inorganic ion transport and metabolism YP_001228747.1 Coenzyme metabolism YP_001228748.1 Coenzyme metabolism YP_001228750.1 DNA replication, recombination, and repair YP_001228752.1 Coenzyme metabolism YP_001228753.1 Coenzyme metabolism YP_001228754.1 Coenzyme metabolism YP_001228755.1 Coenzyme metabolism YP_001228756.1 Coenzyme metabolism YP_001228757.1 Nucleotide transport and metabolism YP_001228759.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001228760.1 Transcription YP_001228763.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001228764.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001228768.1 Nucleotide transport and metabolism YP_001228769.1 Amino acid transport and metabolism YP_001228771.1 Amino acid transport and metabolism YP_001228772.1 Inorganic ion transport and metabolism YP_001228773.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001228774.1 Amino acid transport and metabolism YP_001228776.1 Translation, ribosomal structure and biogenesis YP_001228778.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001228781.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001228784.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001228785.1 Lacks the C-terminal Sucrose-6F-phosphate phosphohydrolase domain (S6PP), present in WH8102, WH7803 and MIT9313. This domain is also missing in MED4 and SS120; Carbohydrate transport and metabolism YP_001228787.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001228788.1 DNA replication, recombination, and repair YP_001228791.1 Amino acid transport and metabolism