-- dump date 20111121_015407 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001305268.1 150019914 5298195 162..1475 1 NC_009616.1 TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator, DnaA C-terminal domain; Chromosomal replication initiator, DnaA; SMART: AAA ATPase; chromosomal replication initiator protein DnaA 1475 5298195 Tmel_0001 Thermosipho melanesiensis BI429 chromosomal replication initiator protein DnaA YP_001305268.1 162 D 391009 CDS YP_001305269.1 150019915 5296486 1517..1699 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 1699 5296486 Tmel_0002 Thermosipho melanesiensis BI429 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_001305269.1 1517 D 391009 CDS YP_001305270.1 150019916 5298453 complement(5349..5702) 1 NC_009616.1 hypothetical protein 5702 5298453 Tmel_0005 Thermosipho melanesiensis BI429 hypothetical protein YP_001305270.1 5349 R 391009 CDS YP_001305271.1 150019917 5296579 complement(6140..6805) 1 NC_009616.1 hypothetical protein 6805 5296579 Tmel_0006 Thermosipho melanesiensis BI429 hypothetical protein YP_001305271.1 6140 R 391009 CDS YP_001305272.1 150019918 5297534 complement(6807..8114) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 8114 5297534 Tmel_0007 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305272.1 6807 R 391009 CDS YP_001305273.1 150019919 5297426 complement(8798..10666) 1 NC_009616.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase 10666 5297426 Tmel_0008 Thermosipho melanesiensis BI429 NADH:flavin oxidoreductase/NADH oxidase YP_001305273.1 8798 R 391009 CDS YP_001305274.1 150019920 5297427 complement(10663..10956) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 10956 5297427 Tmel_0009 Thermosipho melanesiensis BI429 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_001305274.1 10663 R 391009 CDS YP_001305275.1 150019921 5296742 complement(10975..11298) 1 NC_009616.1 PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein 11298 5296742 Tmel_0010 Thermosipho melanesiensis BI429 dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_001305275.1 10975 R 391009 CDS YP_001305276.1 150019922 5296743 complement(11311..11655) 1 NC_009616.1 PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein 11655 5296743 Tmel_0011 Thermosipho melanesiensis BI429 dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_001305276.1 11311 R 391009 CDS YP_001305277.1 150019923 5297834 complement(11672..12544) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 12544 5297834 Tmel_0012 Thermosipho melanesiensis BI429 cobyrinic acid a,c-diamide synthase YP_001305277.1 11672 R 391009 CDS YP_001305278.1 150019924 5296530 complement(12541..13389) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 13389 5296530 Tmel_0013 Thermosipho melanesiensis BI429 cobyrinic acid a,c-diamide synthase YP_001305278.1 12541 R 391009 CDS YP_001305279.1 150019925 5296531 complement(13589..15157) 1 NC_009616.1 TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; putative delta-1-pyrroline-5-carboxylate dehydrogenase 15157 5296531 Tmel_0014 Thermosipho melanesiensis BI429 putative delta-1-pyrroline-5-carboxylate dehydrogenase YP_001305279.1 13589 R 391009 CDS YP_001305280.1 150019926 5296850 15352..17166 1 NC_009616.1 hypothetical protein 17166 5296850 Tmel_0015 Thermosipho melanesiensis BI429 hypothetical protein YP_001305280.1 15352 D 391009 CDS YP_001305281.1 150019927 5296851 17183..18280 1 NC_009616.1 PFAM: basic membrane lipoprotein; basic membrane lipoprotein 18280 5296851 Tmel_0016 Thermosipho melanesiensis BI429 basic membrane lipoprotein YP_001305281.1 17183 D 391009 CDS YP_001305282.1 150019928 5296525 18377..19900 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 19900 5296525 Tmel_0017 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305282.1 18377 D 391009 CDS YP_001305283.1 150019929 5296735 19902..20936 1 NC_009616.1 PFAM: inner-membrane translocator; inner-membrane translocator 20936 5296735 Tmel_0018 Thermosipho melanesiensis BI429 inner-membrane translocator YP_001305283.1 19902 D 391009 CDS YP_001305284.1 150019930 5296736 20933..21892 1 NC_009616.1 PFAM: inner-membrane translocator; inner-membrane translocator 21892 5296736 Tmel_0019 Thermosipho melanesiensis BI429 inner-membrane translocator YP_001305284.1 20933 D 391009 CDS YP_001305285.1 150019931 5297268 21970..22107 1 NC_009616.1 hypothetical protein 22107 5297268 Tmel_0020 Thermosipho melanesiensis BI429 hypothetical protein YP_001305285.1 21970 D 391009 CDS YP_001305286.1 150019932 5297830 complement(22599..23306) 1 NC_009616.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein 23306 5297830 Tmel_0021 Thermosipho melanesiensis BI429 hypothetical protein YP_001305286.1 22599 R 391009 CDS YP_001305287.1 150019933 5297334 complement(23321..24187) 1 NC_009616.1 TIGRFAM: degV family protein; PFAM: DegV family protein; degV family protein 24187 5297334 Tmel_0022 Thermosipho melanesiensis BI429 degV family protein YP_001305287.1 23321 R 391009 CDS YP_001305288.1 150019934 5297648 complement(24177..25511) 1 NC_009616.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 25511 5297648 Tmel_0023 Thermosipho melanesiensis BI429 DNA repair protein RadA YP_001305288.1 24177 R 391009 CDS YP_001305289.1 150019935 5297649 complement(25504..27960) 1 NC_009616.1 PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase 27960 5297649 Tmel_0024 Thermosipho melanesiensis BI429 ATPase YP_001305289.1 25504 R 391009 CDS YP_001305290.1 150019936 5297397 complement(28033..30261) 1 NC_009616.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; phosphotransferase domain-containing protein 30261 5297397 Tmel_0025 Thermosipho melanesiensis BI429 phosphotransferase domain-containing protein YP_001305290.1 28033 R 391009 CDS YP_001305291.1 150019937 5297398 30360..30836 1 NC_009616.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 30836 5297398 Tmel_0026 Thermosipho melanesiensis BI429 phosphodiesterase YP_001305291.1 30360 D 391009 CDS YP_001305292.1 150019938 5296901 30930..31856 1 NC_009616.1 PFAM: Mg2+ transporter protein, CorA family protein; Mg2+ transporter protein, CorA family protein 31856 5296901 Tmel_0027 Thermosipho melanesiensis BI429 Mg2+ transporter protein, CorA family protein YP_001305292.1 30930 D 391009 CDS YP_001305293.1 150019939 5298292 complement(32947..33636) 1 NC_009616.1 hypothetical protein 33636 5298292 Tmel_0029 Thermosipho melanesiensis BI429 hypothetical protein YP_001305293.1 32947 R 391009 CDS YP_001305294.1 150019940 5297160 complement(33675..34613) 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 34613 5297160 Tmel_0030 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305294.1 33675 R 391009 CDS YP_001305295.1 150019941 5297023 complement(34601..35395) 1 NC_009616.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 35395 5297023 Tmel_0031 Thermosipho melanesiensis BI429 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001305295.1 34601 R 391009 CDS YP_001305296.1 150019942 5297024 complement(35380..35934) 1 NC_009616.1 PFAM: isochorismatase hydrolase; isochorismatase hydrolase 35934 5297024 Tmel_0032 Thermosipho melanesiensis BI429 isochorismatase hydrolase YP_001305296.1 35380 R 391009 CDS YP_001305297.1 150019943 5297421 complement(35931..36821) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 36821 5297421 Tmel_0033 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305297.1 35931 R 391009 CDS YP_001305298.1 150019944 5297103 complement(36832..39153) 1 NC_009616.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 39153 5297103 Tmel_0034 Thermosipho melanesiensis BI429 ATP-dependent DNA helicase RecG YP_001305298.1 36832 R 391009 CDS YP_001305299.1 150019945 5297104 complement(39157..39834) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 39834 5297104 Tmel_0035 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305299.1 39157 R 391009 CDS YP_001305300.1 150019946 5297164 39891..40502 1 NC_009616.1 TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic region; thiamine pyrophosphokinase 40502 5297164 Tmel_0036 Thermosipho melanesiensis BI429 thiamine pyrophosphokinase YP_001305300.1 39891 D 391009 CDS YP_001305301.1 150019947 5297165 40481..41539 1 NC_009616.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 41539 5297165 Tmel_0037 Thermosipho melanesiensis BI429 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001305301.1 40481 D 391009 CDS YP_001305302.1 150019948 5297052 41784..42665 1 NC_009616.1 PFAM: periplasmic binding protein; periplasmic binding protein 42665 5297052 Tmel_0038 Thermosipho melanesiensis BI429 periplasmic binding protein YP_001305302.1 41784 D 391009 CDS YP_001305303.1 150019949 5297242 42662..43633 1 NC_009616.1 PFAM: transport system permease protein; ABC-3 protein; transport system permease 43633 5297242 Tmel_0039 Thermosipho melanesiensis BI429 transport system permease YP_001305303.1 42662 D 391009 CDS YP_001305304.1 150019950 5297243 43659..44462 1 NC_009616.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase 44462 5297243 Tmel_0040 Thermosipho melanesiensis BI429 HAD family hydrolase YP_001305304.1 43659 D 391009 CDS YP_001305305.1 150019951 5296873 44469..45089 1 NC_009616.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 45089 5296873 Tmel_0041 Thermosipho melanesiensis BI429 RNA polymerase factor sigma-70 YP_001305305.1 44469 D 391009 CDS YP_001305306.1 150019952 5298110 complement(45676..46128) 1 NC_009616.1 PFAM: 6,7-dimethyl-8-ribityllumazine synthase; riboflavin synthase 46128 5298110 Tmel_0042 Thermosipho melanesiensis BI429 riboflavin synthase YP_001305306.1 45676 R 391009 CDS YP_001305307.1 150019953 5297102 complement(46125..47246) 1 NC_009616.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 47246 5297102 Tmel_0043 Thermosipho melanesiensis BI429 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_001305307.1 46125 R 391009 CDS YP_001305308.1 150019954 5296785 complement(47224..47790) 1 NC_009616.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 47790 5296785 Tmel_0044 Thermosipho melanesiensis BI429 riboflavin synthase subunit alpha YP_001305308.1 47224 R 391009 CDS YP_001305309.1 150019955 5296786 complement(47783..48796) 1 NC_009616.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein; riboflavin biosynthesis protein RibD 48796 5296786 Tmel_0045 Thermosipho melanesiensis BI429 riboflavin biosynthesis protein RibD YP_001305309.1 47783 R 391009 CDS YP_001305310.1 150019956 5297532 complement(48975..50666) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 50666 5297532 Tmel_0046 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305310.1 48975 R 391009 CDS YP_001305311.1 150019957 5297533 complement(50684..51091) 1 NC_009616.1 TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; NifU family SUF system FeS assembly protein 51091 5297533 Tmel_0047 Thermosipho melanesiensis BI429 NifU family SUF system FeS assembly protein YP_001305311.1 50684 R 391009 CDS YP_001305312.1 150019958 5296507 complement(51081..52322) 1 NC_009616.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase, class V; SufS subfamily cysteine desulfurase 52322 5296507 Tmel_0048 Thermosipho melanesiensis BI429 SufS subfamily cysteine desulfurase YP_001305312.1 51081 R 391009 CDS YP_001305313.1 150019959 5296758 complement(52297..53415) 1 NC_009616.1 PFAM: SufBD protein; SufBD protein 53415 5296758 Tmel_0049 Thermosipho melanesiensis BI429 SufBD protein YP_001305313.1 52297 R 391009 CDS YP_001305314.1 150019960 5296759 complement(53426..54817) 1 NC_009616.1 TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; FeS assembly protein SufB 54817 5296759 Tmel_0050 Thermosipho melanesiensis BI429 FeS assembly protein SufB YP_001305314.1 53426 R 391009 CDS YP_001305315.1 150019961 5296547 complement(54822..55565) 1 NC_009616.1 TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; FeS assembly ATPase SufC 55565 5296547 Tmel_0051 Thermosipho melanesiensis BI429 FeS assembly ATPase SufC YP_001305315.1 54822 R 391009 CDS YP_001305316.1 150019962 5296548 complement(55681..57300) 1 NC_009616.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 57300 groEL 5296548 groEL Thermosipho melanesiensis BI429 chaperonin GroEL YP_001305316.1 55681 R 391009 CDS YP_001305317.1 150019963 5297555 complement(57317..57589) 1 NC_009616.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 57589 groES 5297555 groES Thermosipho melanesiensis BI429 co-chaperonin GroES YP_001305317.1 57317 R 391009 CDS YP_001305318.1 150019964 5298449 57948..58328 1 NC_009616.1 PFAM: ribonuclease III; ribonuclease III 58328 5298449 Tmel_0054 Thermosipho melanesiensis BI429 ribonuclease III YP_001305318.1 57948 D 391009 CDS YP_001305319.1 150019965 5297758 58325..60043 1 NC_009616.1 hypothetical protein 60043 5297758 Tmel_0055 Thermosipho melanesiensis BI429 hypothetical protein YP_001305319.1 58325 D 391009 CDS YP_001305320.1 150019966 5297044 60048..61436 1 NC_009616.1 PFAM: peptidase U62, modulator of DNA gyrase; peptidase U62, modulator of DNA gyrase 61436 5297044 Tmel_0056 Thermosipho melanesiensis BI429 peptidase U62, modulator of DNA gyrase YP_001305320.1 60048 D 391009 CDS YP_001305321.1 150019967 5297045 61433..62740 1 NC_009616.1 PFAM: peptidase U62, modulator of DNA gyrase; peptidase U62, modulator of DNA gyrase 62740 5297045 Tmel_0057 Thermosipho melanesiensis BI429 peptidase U62, modulator of DNA gyrase YP_001305321.1 61433 D 391009 CDS YP_001305322.1 150019968 5297823 62849..63910 1 NC_009616.1 PFAM: alanine racemase domain protein; alanine racemase domain-containing protein 63910 5297823 Tmel_0058 Thermosipho melanesiensis BI429 alanine racemase domain-containing protein YP_001305322.1 62849 D 391009 CDS YP_001305323.1 150019969 5297824 complement(63937..65028) 1 NC_009616.1 hypothetical protein 65028 5297824 Tmel_0059 Thermosipho melanesiensis BI429 hypothetical protein YP_001305323.1 63937 R 391009 CDS YP_001305324.1 150019970 5297825 complement(65163..66167) 1 NC_009616.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 66167 queA 5297825 queA Thermosipho melanesiensis BI429 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_001305324.1 65163 R 391009 CDS YP_001305325.1 150019971 5297869 complement(66217..66471) 1 NC_009616.1 PFAM: ribosomal protein S15; ribosomal protein S15 66471 5297869 Tmel_0061 Thermosipho melanesiensis BI429 ribosomal protein S15 YP_001305325.1 66217 R 391009 CDS YP_001305326.1 150019972 5298314 complement(67257..68951) 1 NC_009616.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 68951 5298314 Tmel_0063 Thermosipho melanesiensis BI429 prolyl-tRNA synthetase YP_001305326.1 67257 R 391009 CDS YP_001305327.1 150019973 5297951 complement(68948..70357) 1 NC_009616.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 70357 cysS 5297951 cysS Thermosipho melanesiensis BI429 cysteinyl-tRNA synthetase YP_001305327.1 68948 R 391009 CDS YP_001305328.1 150019974 5296716 complement(70362..71783) 1 NC_009616.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 71783 gltX 5296716 gltX Thermosipho melanesiensis BI429 glutamyl-tRNA synthetase YP_001305328.1 70362 R 391009 CDS YP_001305329.1 150019975 5296717 72024..73235 1 NC_009616.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; uracil-xanthine permease 73235 5296717 Tmel_0066 Thermosipho melanesiensis BI429 uracil-xanthine permease YP_001305329.1 72024 D 391009 CDS YP_001305330.1 150019976 5298378 complement(73811..73936) 1 NC_009616.1 hypothetical protein 73936 5298378 Tmel_0068 Thermosipho melanesiensis BI429 hypothetical protein YP_001305330.1 73811 R 391009 CDS YP_001305331.1 150019977 5297375 complement(73936..74214) 1 NC_009616.1 hypothetical protein 74214 5297375 Tmel_0069 Thermosipho melanesiensis BI429 hypothetical protein YP_001305331.1 73936 R 391009 CDS YP_001305332.1 150019978 5296789 complement(74657..75685) 1 NC_009616.1 hypothetical protein 75685 5296789 Tmel_0070 Thermosipho melanesiensis BI429 hypothetical protein YP_001305332.1 74657 R 391009 CDS YP_001305333.1 150019979 5296790 75769..77061 1 NC_009616.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 77061 5296790 Tmel_0071 Thermosipho melanesiensis BI429 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001305333.1 75769 D 391009 CDS YP_001305334.1 150019980 5296791 77080..77943 1 NC_009616.1 PFAM: protein of unknown function DUF161; hypothetical protein 77943 5296791 Tmel_0072 Thermosipho melanesiensis BI429 hypothetical protein YP_001305334.1 77080 D 391009 CDS YP_001305335.1 150019981 5296710 77953..78483 1 NC_009616.1 PFAM: isochorismatase hydrolase; isochorismatase hydrolase 78483 5296710 Tmel_0073 Thermosipho melanesiensis BI429 isochorismatase hydrolase YP_001305335.1 77953 D 391009 CDS YP_001305336.1 150019982 5296711 78485..79426 1 NC_009616.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; cation diffusion facilitator family transporter 79426 5296711 Tmel_0074 Thermosipho melanesiensis BI429 cation diffusion facilitator family transporter YP_001305336.1 78485 D 391009 CDS YP_001305337.1 150019983 5297965 79389..80480 1 NC_009616.1 hypothetical protein 80480 5297965 Tmel_0075 Thermosipho melanesiensis BI429 hypothetical protein YP_001305337.1 79389 D 391009 CDS YP_001305338.1 150019984 5297296 complement(80501..81499) 1 NC_009616.1 TIGRFAM: galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 81499 5297296 Tmel_0076 Thermosipho melanesiensis BI429 galactose-1-phosphate uridylyltransferase YP_001305338.1 80501 R 391009 CDS YP_001305339.1 150019985 5297297 complement(81513..82958) 1 NC_009616.1 TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; glycogen/starch synthase 82958 5297297 Tmel_0077 Thermosipho melanesiensis BI429 glycogen/starch synthase YP_001305339.1 81513 R 391009 CDS YP_001305340.1 150019986 5296926 complement(82964..83593) 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 83593 5296926 Tmel_0078 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001305340.1 82964 R 391009 CDS YP_001305341.1 150019987 5296927 complement(83583..85277) 1 NC_009616.1 TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase; sigma-54 dependent trancsriptional regulator 85277 5296927 Tmel_0079 Thermosipho melanesiensis BI429 sigma-54 dependent trancsriptional regulator YP_001305341.1 83583 R 391009 CDS YP_001305342.1 150019988 5297971 complement(85279..85689) 1 NC_009616.1 PFAM: protein of unknown function UPF0047; hypothetical protein 85689 5297971 Tmel_0080 Thermosipho melanesiensis BI429 hypothetical protein YP_001305342.1 85279 R 391009 CDS YP_001305343.1 150019989 5297718 complement(85686..86618) 1 NC_009616.1 PFAM: protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; D-alanine--D-alanine ligase 86618 5297718 Tmel_0081 Thermosipho melanesiensis BI429 D-alanine--D-alanine ligase YP_001305343.1 85686 R 391009 CDS YP_001305344.1 150019990 5297719 complement(86615..88240) 1 NC_009616.1 PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 88240 5297719 Tmel_0082 Thermosipho melanesiensis BI429 cobalamin B12-binding domain-containing protein YP_001305344.1 86615 R 391009 CDS YP_001305345.1 150019991 5297335 complement(88237..89316) 1 NC_009616.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; NAD/NADP octopine/nopaline dehydrogenase 89316 5297335 Tmel_0083 Thermosipho melanesiensis BI429 NAD/NADP octopine/nopaline dehydrogenase YP_001305345.1 88237 R 391009 CDS YP_001305346.1 150019992 5297336 complement(89330..90280) 1 NC_009616.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 90280 5297336 Tmel_0084 Thermosipho melanesiensis BI429 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_001305346.1 89330 R 391009 CDS YP_001305347.1 150019993 5297383 complement(90286..91497) 1 NC_009616.1 PFAM: MOFRL domain protein; hydroxypyruvate reductase 91497 5297383 Tmel_0085 Thermosipho melanesiensis BI429 hydroxypyruvate reductase YP_001305347.1 90286 R 391009 CDS YP_001305348.1 150019994 5297085 complement(91502..92341) 1 NC_009616.1 TIGRFAM: NAD+ synthetase; PFAM: NAD+ synthase; NAD+ synthetase 92341 5297085 Tmel_0086 Thermosipho melanesiensis BI429 NAD+ synthetase YP_001305348.1 91502 R 391009 CDS YP_001305349.1 150019995 5297086 complement(92325..93446) 1 NC_009616.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 93446 5297086 Tmel_0087 Thermosipho melanesiensis BI429 chaperone protein DnaJ YP_001305349.1 92325 R 391009 CDS YP_001305350.1 150019996 5297027 complement(93451..94002) 1 NC_009616.1 PFAM: GrpE protein; GrpE protein 94002 5297027 Tmel_0088 Thermosipho melanesiensis BI429 GrpE protein YP_001305350.1 93451 R 391009 CDS YP_001305351.1 150019997 5297028 complement(94018..95031) 1 NC_009616.1 TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein; heat-inducible transcription repressor HrcA 95031 5297028 Tmel_0089 Thermosipho melanesiensis BI429 heat-inducible transcription repressor HrcA YP_001305351.1 94018 R 391009 CDS YP_001305352.1 150019998 5297767 complement(95135..96403) 1 NC_009616.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; major facilitator transporter 96403 5297767 Tmel_0090 Thermosipho melanesiensis BI429 major facilitator transporter YP_001305352.1 95135 R 391009 CDS YP_001305353.1 150019999 5296880 complement(96403..96906) 1 NC_009616.1 PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein; 3H domain-containing protein 96906 5296880 Tmel_0091 Thermosipho melanesiensis BI429 3H domain-containing protein YP_001305353.1 96403 R 391009 CDS YP_001305354.1 150020000 5296881 complement(97024..97653) 1 NC_009616.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; hemolysin III family channel protein 97653 5296881 Tmel_0092 Thermosipho melanesiensis BI429 hemolysin III family channel protein YP_001305354.1 97024 R 391009 CDS YP_001305355.1 150020001 5297932 complement(97650..98069) 1 NC_009616.1 PFAM: peptidylprolyl isomerase, FKBP-type; FKBP-type peptidylprolyl isomerase 98069 5297932 Tmel_0093 Thermosipho melanesiensis BI429 FKBP-type peptidylprolyl isomerase YP_001305355.1 97650 R 391009 CDS YP_001305356.1 150020002 5297933 complement(98443..99663) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 99663 5297933 Tmel_0094 Thermosipho melanesiensis BI429 major facilitator transporter YP_001305356.1 98443 R 391009 CDS YP_001305357.1 150020003 5297973 complement(99647..100597) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 100597 5297973 Tmel_0095 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305357.1 99647 R 391009 CDS YP_001305358.1 150020004 5297357 100684..101703 1 NC_009616.1 PFAM: peptidase M18, aminopeptidase I; peptidase M20; peptidase M42 family protein; peptidase M42 family protein 101703 5297357 Tmel_0096 Thermosipho melanesiensis BI429 peptidase M42 family protein YP_001305358.1 100684 D 391009 CDS YP_001305359.1 150020005 5297358 101703..102707 1 NC_009616.1 PFAM: peptidase M42 family protein; cellulase 102707 5297358 Tmel_0097 Thermosipho melanesiensis BI429 cellulase YP_001305359.1 101703 D 391009 CDS YP_001305360.1 150020006 5296487 complement(102732..102959) 1 NC_009616.1 TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; DNA-directed RNA polymerase subunit omega 102959 5296487 Tmel_0098 Thermosipho melanesiensis BI429 DNA-directed RNA polymerase subunit omega YP_001305360.1 102732 R 391009 CDS YP_001305361.1 150020007 5296488 complement(102961..103575) 1 NC_009616.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 103575 gmk 5296488 gmk Thermosipho melanesiensis BI429 guanylate kinase YP_001305361.1 102961 R 391009 CDS YP_001305362.1 150020008 5297144 complement(103577..103861) 1 NC_009616.1 PFAM: protein of unknown function DUF370; hypothetical protein 103861 5297144 Tmel_0100 Thermosipho melanesiensis BI429 hypothetical protein YP_001305362.1 103577 R 391009 CDS YP_001305363.1 150020009 5296694 complement(103880..104752) 1 NC_009616.1 PFAM: YicC N-terminal domain protein; hypothetical protein 104752 5296694 Tmel_0101 Thermosipho melanesiensis BI429 hypothetical protein YP_001305363.1 103880 R 391009 CDS YP_001305364.1 150020010 5296695 complement(104889..105425) 1 NC_009616.1 PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate ferredoxin/flavodoxin oxidoreductase 105425 5296695 Tmel_0102 Thermosipho melanesiensis BI429 pyruvate ferredoxin/flavodoxin oxidoreductase YP_001305364.1 104889 R 391009 CDS YP_001305365.1 150020011 5296847 complement(105422..106174) 1 NC_009616.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein 106174 5296847 Tmel_0103 Thermosipho melanesiensis BI429 thiamine pyrophosphate binding domain-containing protein YP_001305365.1 105422 R 391009 CDS YP_001305366.1 150020012 5296848 complement(106180..107238) 1 NC_009616.1 catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase 107238 5296848 Tmel_0104 Thermosipho melanesiensis BI429 2-ketoisovalerate ferredoxin reductase YP_001305366.1 106180 R 391009 CDS YP_001305367.1 150020013 5296518 complement(107251..107472) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 107472 5296518 Tmel_0105 Thermosipho melanesiensis BI429 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_001305367.1 107251 R 391009 CDS YP_001305368.1 150020014 5297294 complement(107486..108130) 1 NC_009616.1 hypothetical protein 108130 5297294 Tmel_0106 Thermosipho melanesiensis BI429 hypothetical protein YP_001305368.1 107486 R 391009 CDS YP_001305369.1 150020015 5297295 complement(108123..109214) 1 NC_009616.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 109214 5297295 Tmel_0107 Thermosipho melanesiensis BI429 butyrate kinase YP_001305369.1 108123 R 391009 CDS YP_001305370.1 150020016 5296990 complement(109207..110118) 1 NC_009616.1 PFAM: phosphate acetyl/butaryl transferase; phosphate butyryltransferase 110118 5296990 Tmel_0108 Thermosipho melanesiensis BI429 phosphate butyryltransferase YP_001305370.1 109207 R 391009 CDS YP_001305371.1 150020017 5296991 complement(110102..111172) 1 NC_009616.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 111172 5296991 Tmel_0109 Thermosipho melanesiensis BI429 butyrate kinase YP_001305371.1 110102 R 391009 CDS YP_001305372.1 150020018 5297626 complement(111172..112407) 1 NC_009616.1 PFAM: aminotransferase, class I and II; GntR family transcriptional regulator 112407 5297626 Tmel_0110 Thermosipho melanesiensis BI429 GntR family transcriptional regulator YP_001305372.1 111172 R 391009 CDS YP_001305373.1 150020019 5296514 112674..113816 1 NC_009616.1 PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; class V aminotransferase 113816 5296514 Tmel_0111 Thermosipho melanesiensis BI429 class V aminotransferase YP_001305373.1 112674 D 391009 CDS YP_001305374.1 150020020 5296515 113816..114727 1 NC_009616.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; phosphoglycerate dehydrogenase 114727 5296515 Tmel_0112 Thermosipho melanesiensis BI429 phosphoglycerate dehydrogenase YP_001305374.1 113816 D 391009 CDS YP_001305375.1 150020021 5297329 complement(114774..116468) 1 NC_009616.1 PFAM: carbon starvation protein CstA; carbon starvation protein CstA 116468 5297329 Tmel_0113 Thermosipho melanesiensis BI429 carbon starvation protein CstA YP_001305375.1 114774 R 391009 CDS YP_001305376.1 150020022 5297330 complement(116610..117290) 1 NC_009616.1 PFAM: response regulator receiver; LytTr DNA-binding region; LytTR family two component transcriptional regulator 117290 5297330 Tmel_0114 Thermosipho melanesiensis BI429 LytTR family two component transcriptional regulator YP_001305376.1 116610 R 391009 CDS YP_001305377.1 150020023 5296944 complement(117287..118945) 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; signal transduction histidine kinase LytS 118945 5296944 Tmel_0115 Thermosipho melanesiensis BI429 signal transduction histidine kinase LytS YP_001305377.1 117287 R 391009 CDS YP_001305378.1 150020024 5297203 complement(118939..119217) 1 NC_009616.1 hypothetical protein 119217 5297203 Tmel_0116 Thermosipho melanesiensis BI429 hypothetical protein YP_001305378.1 118939 R 391009 CDS YP_001305379.1 150020025 5298379 119761..120966 1 NC_009616.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 120966 5298379 Tmel_0117 Thermosipho melanesiensis BI429 peptidase YP_001305379.1 119761 D 391009 CDS YP_001305380.1 150020026 5296519 120969..121958 1 NC_009616.1 PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase carbamoyl phosphate-binding subunit 121958 5296519 Tmel_0118 Thermosipho melanesiensis BI429 aspartate/ornithine carbamoyltransferase carbamoyl phosphate-binding subunit YP_001305380.1 120969 D 391009 CDS YP_001305381.1 150020027 5296520 121959..123251 1 NC_009616.1 PFAM: amidohydrolase; dihydropyrimidinase 123251 5296520 Tmel_0119 Thermosipho melanesiensis BI429 dihydropyrimidinase YP_001305381.1 121959 D 391009 CDS YP_001305382.1 150020028 5296554 123251..124531 1 NC_009616.1 PFAM: amidohydrolase; amidohydrolase 124531 5296554 Tmel_0120 Thermosipho melanesiensis BI429 amidohydrolase YP_001305382.1 123251 D 391009 CDS YP_001305383.1 150020029 5297847 124544..125626 1 NC_009616.1 TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; dihydroorotate dehydrogenase family protein 125626 5297847 Tmel_0121 Thermosipho melanesiensis BI429 dihydroorotate dehydrogenase family protein YP_001305383.1 124544 D 391009 CDS YP_001305384.1 150020030 5297995 126232..126495 1 NC_009616.1 PFAM: Stage V sporulation protein S; stage V sporulation protein S 126495 5297995 Tmel_0122 Thermosipho melanesiensis BI429 stage V sporulation protein S YP_001305384.1 126232 D 391009 CDS YP_001305385.1 150020031 5296552 complement(126544..128091) 1 NC_009616.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 128091 ushA 5296552 ushA Thermosipho melanesiensis BI429 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_001305385.1 126544 R 391009 CDS YP_001305386.1 150020032 5296553 complement(128131..129852) 1 NC_009616.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 129852 5296553 Tmel_0124 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305386.1 128131 R 391009 CDS YP_001305387.1 150020033 5297460 complement(129858..132002) 1 NC_009616.1 hypothetical protein 132002 5297460 Tmel_0125 Thermosipho melanesiensis BI429 hypothetical protein YP_001305387.1 129858 R 391009 CDS YP_001305388.1 150020034 5297230 complement(132013..132627) 1 NC_009616.1 hypothetical protein 132627 5297230 Tmel_0126 Thermosipho melanesiensis BI429 hypothetical protein YP_001305388.1 132013 R 391009 CDS YP_001305389.1 150020035 5297231 complement(132635..135001) 1 NC_009616.1 hypothetical protein 135001 5297231 Tmel_0127 Thermosipho melanesiensis BI429 hypothetical protein YP_001305389.1 132635 R 391009 CDS YP_001305390.1 150020036 5297942 complement(135001..135528) 1 NC_009616.1 PFAM: protein of unknown function DUF151; hypothetical protein 135528 5297942 Tmel_0128 Thermosipho melanesiensis BI429 hypothetical protein YP_001305390.1 135001 R 391009 CDS YP_001305391.1 150020037 5297943 complement(135515..136270) 1 NC_009616.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 136270 5297943 Tmel_0129 Thermosipho melanesiensis BI429 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001305391.1 135515 R 391009 CDS YP_001305392.1 150020038 5297647 complement(136267..137436) 1 NC_009616.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 137436 5297647 Tmel_0130 Thermosipho melanesiensis BI429 thiamine biosynthesis protein ThiI YP_001305392.1 136267 R 391009 CDS YP_001305393.1 150020039 5296667 complement(137473..137745) 1 NC_009616.1 PFAM: protein of unknown function DUF156; hypothetical protein 137745 5296667 Tmel_0131 Thermosipho melanesiensis BI429 hypothetical protein YP_001305393.1 137473 R 391009 CDS YP_001305394.1 150020040 5296668 138743..139270 1 NC_009616.1 PFAM: NLP/P60 protein; NLP/P60 protein 139270 5296668 Tmel_0132 Thermosipho melanesiensis BI429 NLP/P60 protein YP_001305394.1 138743 D 391009 CDS YP_001305395.1 150020041 5297337 complement(139504..141345) 1 NC_009616.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter transmembrane region 141345 5297337 Tmel_0133 Thermosipho melanesiensis BI429 ABC transporter transmembrane region YP_001305395.1 139504 R 391009 CDS YP_001305396.1 150020042 5297338 complement(141342..143066) 1 NC_009616.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 143066 5297338 Tmel_0134 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305396.1 141342 R 391009 CDS YP_001305397.1 150020043 5297968 complement(143050..143499) 1 NC_009616.1 PFAM: regulatory protein, MarR; MarR family transcriptional regulator 143499 5297968 Tmel_0135 Thermosipho melanesiensis BI429 MarR family transcriptional regulator YP_001305397.1 143050 R 391009 CDS YP_001305398.1 150020044 5296482 143605..147528 1 NC_009616.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain-containing protein 147528 5296482 Tmel_0136 Thermosipho melanesiensis BI429 alpha-2-macroglobulin domain-containing protein YP_001305398.1 143605 D 391009 CDS YP_001305399.1 150020045 5296483 147590..147949 1 NC_009616.1 hypothetical protein 147949 5296483 Tmel_0137 Thermosipho melanesiensis BI429 hypothetical protein YP_001305399.1 147590 D 391009 CDS YP_001305400.1 150020046 5297118 147906..148529 1 NC_009616.1 PFAM: protein of unknown function DUF1175; hypothetical protein 148529 5297118 Tmel_0138 Thermosipho melanesiensis BI429 hypothetical protein YP_001305400.1 147906 D 391009 CDS YP_001305401.1 150020047 5297119 complement(148571..149785) 1 NC_009616.1 PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 149785 5297119 Tmel_0139 Thermosipho melanesiensis BI429 iron-containing alcohol dehydrogenase YP_001305401.1 148571 R 391009 CDS YP_001305402.1 150020048 5297959 149930..150448 1 NC_009616.1 hypothetical protein 150448 5297959 Tmel_0140 Thermosipho melanesiensis BI429 hypothetical protein YP_001305402.1 149930 D 391009 CDS YP_001305403.1 150020049 5296730 complement(150467..151801) 1 NC_009616.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 151801 5296730 Tmel_0141 Thermosipho melanesiensis BI429 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001305403.1 150467 R 391009 CDS YP_001305404.1 150020050 5296731 complement(151944..153473) 1 NC_009616.1 PFAM: Abortive infection protein; abortive infection protein 153473 5296731 Tmel_0142 Thermosipho melanesiensis BI429 abortive infection protein YP_001305404.1 151944 R 391009 CDS YP_001305405.1 150020051 5297889 complement(153522..153917) 1 NC_009616.1 hypothetical protein 153917 5297889 Tmel_0143 Thermosipho melanesiensis BI429 hypothetical protein YP_001305405.1 153522 R 391009 CDS YP_001305406.1 150020052 5297890 complement(154175..155788) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 155788 5297890 Tmel_0144 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305406.1 154175 R 391009 CDS YP_001305407.1 150020053 5297388 complement(155939..156235) 1 NC_009616.1 hypothetical protein 156235 5297388 Tmel_0145 Thermosipho melanesiensis BI429 hypothetical protein YP_001305407.1 155939 R 391009 CDS YP_001305408.1 150020054 5297087 complement(156237..157946) 1 NC_009616.1 TIGRFAM: oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; M3 family oligoendopeptidase 157946 5297087 Tmel_0146 Thermosipho melanesiensis BI429 M3 family oligoendopeptidase YP_001305408.1 156237 R 391009 CDS YP_001305409.1 150020055 5297088 complement(157930..159318) 1 NC_009616.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; MATE efflux family protein 159318 5297088 Tmel_0147 Thermosipho melanesiensis BI429 MATE efflux family protein YP_001305409.1 157930 R 391009 CDS YP_001305410.1 150020056 5296503 159437..160396 1 NC_009616.1 PFAM: aldo/keto reductase; aldo/keto reductase 160396 5296503 Tmel_0148 Thermosipho melanesiensis BI429 aldo/keto reductase YP_001305410.1 159437 D 391009 CDS YP_001305411.1 150020057 5296504 160398..161594 1 NC_009616.1 PFAM: peptidase M29, aminopeptidase II; peptidase M29, aminopeptidase II 161594 5296504 Tmel_0149 Thermosipho melanesiensis BI429 peptidase M29, aminopeptidase II YP_001305411.1 160398 D 391009 CDS YP_001305412.1 150020058 5297802 complement(161580..162596) 1 NC_009616.1 PFAM: ABC-2 type transporter; ABC-2 type transporter 162596 5297802 Tmel_0150 Thermosipho melanesiensis BI429 ABC-2 type transporter YP_001305412.1 161580 R 391009 CDS YP_001305413.1 150020059 5297794 complement(162598..163449) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 163449 5297794 Tmel_0151 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305413.1 162598 R 391009 CDS YP_001305414.1 150020060 5297795 complement(163446..164423) 1 NC_009616.1 PFAM: ABC-2 type transporter; ABC-2 type transporter 164423 5297795 Tmel_0152 Thermosipho melanesiensis BI429 ABC-2 type transporter YP_001305414.1 163446 R 391009 CDS YP_001305415.1 150020061 5297432 complement(164416..164955) 1 NC_009616.1 PFAM: Appr-1-p processing domain protein; appr-1-p processing domain-containing protein 164955 5297432 Tmel_0153 Thermosipho melanesiensis BI429 appr-1-p processing domain-containing protein YP_001305415.1 164416 R 391009 CDS YP_001305416.1 150020062 5297433 complement(164939..166171) 1 NC_009616.1 PFAM: AAA ATPase, central domain protein; recombination factor protein RarA 166171 5297433 Tmel_0154 Thermosipho melanesiensis BI429 recombination factor protein RarA YP_001305416.1 164939 R 391009 CDS YP_001305417.1 150020063 5297954 complement(166140..167072) 1 NC_009616.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; NAD-dependent epimerase/dehydratase 167072 5297954 Tmel_0155 Thermosipho melanesiensis BI429 NAD-dependent epimerase/dehydratase YP_001305417.1 166140 R 391009 CDS YP_001305418.1 150020064 5297008 complement(167072..167575) 1 NC_009616.1 PFAM: iron dependent repressor; iron dependent repressor 167575 5297008 Tmel_0156 Thermosipho melanesiensis BI429 iron dependent repressor YP_001305418.1 167072 R 391009 CDS YP_001305419.1 150020065 5297009 complement(167565..168167) 1 NC_009616.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; phage SPO1 DNA polymerase-like protein 168167 5297009 Tmel_0157 Thermosipho melanesiensis BI429 phage SPO1 DNA polymerase-like protein YP_001305419.1 167565 R 391009 CDS YP_001305420.1 150020066 5297813 168369..171014 1 NC_009616.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 171014 5297813 Tmel_0158 Thermosipho melanesiensis BI429 pyruvate phosphate dikinase YP_001305420.1 168369 D 391009 CDS YP_001305421.1 150020067 5297814 171072..171482 1 NC_009616.1 hypothetical protein 171482 5297814 Tmel_0159 Thermosipho melanesiensis BI429 hypothetical protein YP_001305421.1 171072 D 391009 CDS YP_001305422.1 150020068 5296987 171479..172831 1 NC_009616.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 172831 glmU 5296987 glmU Thermosipho melanesiensis BI429 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001305422.1 171479 D 391009 CDS YP_001305423.1 150020069 5296687 172812..173762 1 NC_009616.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 173762 5296687 Tmel_0161 Thermosipho melanesiensis BI429 ribose-phosphate pyrophosphokinase YP_001305423.1 172812 D 391009 CDS YP_001305424.1 150020070 5296688 173797..174447 1 NC_009616.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 174447 5296688 Tmel_0162 Thermosipho melanesiensis BI429 50S ribosomal protein L25/general stress protein Ctc YP_001305424.1 173797 D 391009 CDS YP_001305425.1 150020071 5297686 174509..174985 1 NC_009616.1 PFAM: peptidyl-tRNA hydrolase; aminoacyl-tRNA hydrolase 174985 5297686 Tmel_0163 Thermosipho melanesiensis BI429 aminoacyl-tRNA hydrolase YP_001305425.1 174509 D 391009 CDS YP_001305426.1 150020072 5297687 174982..175407 1 NC_009616.1 hypothetical protein 175407 5297687 Tmel_0164 Thermosipho melanesiensis BI429 hypothetical protein YP_001305426.1 174982 D 391009 CDS YP_001305427.1 150020073 5297384 175448..177007 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 177007 5297384 Tmel_0165 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305427.1 175448 D 391009 CDS YP_001305428.1 150020074 5297255 177021..178181 1 NC_009616.1 hypothetical protein 178181 5297255 Tmel_0166 Thermosipho melanesiensis BI429 hypothetical protein YP_001305428.1 177021 D 391009 CDS YP_001305429.1 150020075 5297256 178174..178620 1 NC_009616.1 adenylylsulfate kinase-like kinase 178620 5297256 Tmel_0167 Thermosipho melanesiensis BI429 adenylylsulfate kinase-like kinase YP_001305429.1 178174 D 391009 CDS YP_001305430.1 150020076 5297962 178621..181386 1 NC_009616.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 181386 uvrA 5297962 uvrA Thermosipho melanesiensis BI429 excinuclease ABC subunit A YP_001305430.1 178621 D 391009 CDS YP_001305431.1 150020077 5297963 181388..182236 1 NC_009616.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; phage integrase family protein 182236 5297963 Tmel_0169 Thermosipho melanesiensis BI429 phage integrase family protein YP_001305431.1 181388 D 391009 CDS YP_001305432.1 150020078 5297574 complement(182498..182659) 1 NC_009616.1 hypothetical protein 182659 5297574 Tmel_0170 Thermosipho melanesiensis BI429 hypothetical protein YP_001305432.1 182498 R 391009 CDS YP_001305433.1 150020079 5297090 183092..183676 1 NC_009616.1 hypothetical protein 183676 5297090 Tmel_0171 Thermosipho melanesiensis BI429 hypothetical protein YP_001305433.1 183092 D 391009 CDS YP_001305434.1 150020080 5297091 183772..184362 1 NC_009616.1 hypothetical protein 184362 5297091 Tmel_0172 Thermosipho melanesiensis BI429 hypothetical protein YP_001305434.1 183772 D 391009 CDS YP_001305435.1 150020081 5297634 184424..185053 1 NC_009616.1 hypothetical protein 185053 5297634 Tmel_0173 Thermosipho melanesiensis BI429 hypothetical protein YP_001305435.1 184424 D 391009 CDS YP_001305436.1 150020082 5297635 complement(185185..186474) 1 NC_009616.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 186474 eno 5297635 eno Thermosipho melanesiensis BI429 phosphopyruvate hydratase YP_001305436.1 185185 R 391009 CDS YP_001305437.1 150020083 5298296 complement(186600..187805) 1 NC_009616.1 hypothetical protein 187805 5298296 Tmel_0175 Thermosipho melanesiensis BI429 hypothetical protein YP_001305437.1 186600 R 391009 CDS YP_001305438.1 150020084 5298309 complement(187844..188875) 1 NC_009616.1 PFAM: S-layer domain protein domain protein; S-layer domain-containing protein 188875 5298309 Tmel_0176 Thermosipho melanesiensis BI429 S-layer domain-containing protein YP_001305438.1 187844 R 391009 CDS YP_001305439.1 150020085 5298310 complement(188976..190172) 1 NC_009616.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 190172 5298310 Tmel_0177 Thermosipho melanesiensis BI429 tyrosyl-tRNA synthetase YP_001305439.1 188976 R 391009 CDS YP_001305440.1 150020086 5298160 complement(190184..190414) 1 NC_009616.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; preprotein translocase subunit SecG 190414 5298160 Tmel_0178 Thermosipho melanesiensis BI429 preprotein translocase subunit SecG YP_001305440.1 190184 R 391009 CDS YP_001305441.1 150020087 5298161 complement(190473..192248) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 192248 5298161 Tmel_0179 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305441.1 190473 R 391009 CDS YP_001305442.1 150020088 5298123 complement(192261..193283) 1 NC_009616.1 PFAM: putative RNA methylase; putative RNA methylase 193283 5298123 Tmel_0180 Thermosipho melanesiensis BI429 putative RNA methylase YP_001305442.1 192261 R 391009 CDS YP_001305443.1 150020089 5298005 complement(193280..193597) 1 NC_009616.1 PFAM: protein of unknown function DUF190; hypothetical protein 193597 5298005 Tmel_0181 Thermosipho melanesiensis BI429 hypothetical protein YP_001305443.1 193280 R 391009 CDS YP_001305444.1 150020090 5298006 complement(193594..193971) 1 NC_009616.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; CrcB protein 193971 5298006 Tmel_0182 Thermosipho melanesiensis BI429 CrcB protein YP_001305444.1 193594 R 391009 CDS YP_001305445.1 150020091 5298156 complement(193968..194444) 1 NC_009616.1 hypothetical protein 194444 5298156 Tmel_0183 Thermosipho melanesiensis BI429 hypothetical protein YP_001305445.1 193968 R 391009 CDS YP_001305446.1 150020092 5298157 complement(194441..195016) 1 NC_009616.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 195016 5298157 Tmel_0184 Thermosipho melanesiensis BI429 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase YP_001305446.1 194441 R 391009 CDS YP_001305447.1 150020093 5298068 complement(195027..195485) 1 NC_009616.1 PFAM: protein of unknown function DUF163; hypothetical protein 195485 5298068 Tmel_0185 Thermosipho melanesiensis BI429 hypothetical protein YP_001305447.1 195027 R 391009 CDS YP_001305448.1 150020094 5298447 complement(195482..196009) 1 NC_009616.1 PFAM: protein of unknown function DUF501; hypothetical protein 196009 5298447 Tmel_0186 Thermosipho melanesiensis BI429 hypothetical protein YP_001305448.1 195482 R 391009 CDS YP_001305449.1 150020095 5298448 complement(195982..196758) 1 NC_009616.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; conserved hypothetical protein 95; methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; ribosomal L11 methyltransferase 196758 5298448 Tmel_0187 Thermosipho melanesiensis BI429 ribosomal L11 methyltransferase YP_001305449.1 195982 R 391009 CDS YP_001305450.1 150020096 5298407 complement(196759..197574) 1 NC_009616.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; peptidase M23B 197574 5298407 Tmel_0188 Thermosipho melanesiensis BI429 peptidase M23B YP_001305450.1 196759 R 391009 CDS YP_001305451.1 150020097 5298408 197806..198186 1 NC_009616.1 hypothetical protein 198186 5298408 Tmel_0189 Thermosipho melanesiensis BI429 hypothetical protein YP_001305451.1 197806 D 391009 CDS YP_001305452.1 150020098 5298388 198192..199010 1 NC_009616.1 PFAM: protein of unknown function DUF849; hypothetical protein 199010 5298388 Tmel_0190 Thermosipho melanesiensis BI429 hypothetical protein YP_001305452.1 198192 D 391009 CDS YP_001305453.1 150020099 5298354 199015..200046 1 NC_009616.1 hypothetical protein 200046 5298354 Tmel_0191 Thermosipho melanesiensis BI429 hypothetical protein YP_001305453.1 199015 D 391009 CDS YP_001305454.1 150020100 5298355 200059..201330 1 NC_009616.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 201330 5298355 Tmel_0192 Thermosipho melanesiensis BI429 lysine 2,3-aminomutase YodO family protein YP_001305454.1 200059 D 391009 CDS YP_001305455.1 150020101 5298275 201327..201737 1 NC_009616.1 PFAM: MaoC domain protein dehydratase; dehydratase 201737 5298275 Tmel_0193 Thermosipho melanesiensis BI429 dehydratase YP_001305455.1 201327 D 391009 CDS YP_001305456.1 150020102 5298276 201695..202705 1 NC_009616.1 hypothetical protein 202705 5298276 Tmel_0194 Thermosipho melanesiensis BI429 hypothetical protein YP_001305456.1 201695 D 391009 CDS YP_001305457.1 150020103 5298389 202689..204029 1 NC_009616.1 PFAM: DNA mismatch repair protein MutS domain protein; DNA mismatch repair protein MutS domain-containing protein 204029 5298389 Tmel_0195 Thermosipho melanesiensis BI429 DNA mismatch repair protein MutS domain-containing protein YP_001305457.1 202689 D 391009 CDS YP_001305458.1 150020104 5298189 204019..205581 1 NC_009616.1 PFAM: D-Lysine 5,6-aminomutase alpha subunit; D-lysine 5,6-aminomutase alpha subunit 205581 5298189 Tmel_0196 Thermosipho melanesiensis BI429 D-lysine 5,6-aminomutase alpha subunit YP_001305458.1 204019 D 391009 CDS YP_001305459.1 150020105 5298190 205578..206363 1 NC_009616.1 PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 206363 5298190 Tmel_0197 Thermosipho melanesiensis BI429 cobalamin B12-binding domain-containing protein YP_001305459.1 205578 D 391009 CDS YP_001305460.1 150020106 5297998 complement(206369..207511) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 207511 5297998 Tmel_0198 Thermosipho melanesiensis BI429 major facilitator transporter YP_001305460.1 206369 R 391009 CDS YP_001305461.1 150020107 5297999 complement(207520..208146) 1 NC_009616.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein 208146 5297999 Tmel_0199 Thermosipho melanesiensis BI429 hypothetical protein YP_001305461.1 207520 R 391009 CDS YP_001305462.1 150020108 5298158 complement(208149..208541) 1 NC_009616.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 208541 5298158 Tmel_0200 Thermosipho melanesiensis BI429 7-cyano-7-deazaguanine reductase YP_001305462.1 208149 R 391009 CDS YP_001305463.1 150020109 5298412 complement(211151..212509) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 212509 5298412 Tmel_0204 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305463.1 211151 R 391009 CDS YP_001305464.1 150020110 5298267 complement(212493..212873) 1 NC_009616.1 thioesterase-like protein 212873 5298267 Tmel_0205 Thermosipho melanesiensis BI429 thioesterase-like protein YP_001305464.1 212493 R 391009 CDS YP_001305465.1 150020111 5298144 complement(212851..214704) 1 NC_009616.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATP-dependent metalloprotease FtsH 214704 5298144 Tmel_0206 Thermosipho melanesiensis BI429 ATP-dependent metalloprotease FtsH YP_001305465.1 212851 R 391009 CDS YP_001305466.1 150020112 5298145 complement(214701..215972) 1 NC_009616.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; tRNA(Ile)-lysidine synthetase 215972 5298145 Tmel_0207 Thermosipho melanesiensis BI429 tRNA(Ile)-lysidine synthetase YP_001305466.1 214701 R 391009 CDS YP_001305467.1 150020113 5298304 216055..217059 1 NC_009616.1 PFAM: peptidase M20; peptidase M42 family protein; peptidase M42 family protein 217059 5298304 Tmel_0208 Thermosipho melanesiensis BI429 peptidase M42 family protein YP_001305467.1 216055 D 391009 CDS YP_001305468.1 150020114 5298417 217043..217741 1 NC_009616.1 hypothetical protein 217741 5298417 Tmel_0209 Thermosipho melanesiensis BI429 hypothetical protein YP_001305468.1 217043 D 391009 CDS YP_001305469.1 150020115 5298418 217753..218505 1 NC_009616.1 PFAM: Bacitracin resistance protein BacA; bacitracin resistance protein BacA 218505 5298418 Tmel_0210 Thermosipho melanesiensis BI429 bacitracin resistance protein BacA YP_001305469.1 217753 D 391009 CDS YP_001305470.1 150020116 5298335 218502..219698 1 NC_009616.1 TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; imidazolonepropionase 219698 5298335 Tmel_0211 Thermosipho melanesiensis BI429 imidazolonepropionase YP_001305470.1 218502 D 391009 CDS YP_001305471.1 150020117 5298336 219685..220023 1 NC_009616.1 PFAM: protein of unknown function DUF1312; hypothetical protein 220023 5298336 Tmel_0212 Thermosipho melanesiensis BI429 hypothetical protein YP_001305471.1 219685 D 391009 CDS YP_001305472.1 150020118 5298237 220017..220502 1 NC_009616.1 PFAM: Heptaprenyl diphosphate synthase component I; heptaprenyl diphosphate synthase component I 220502 5298237 Tmel_0213 Thermosipho melanesiensis BI429 heptaprenyl diphosphate synthase component I YP_001305472.1 220017 D 391009 CDS YP_001305473.1 150020119 5298442 220480..221028 1 NC_009616.1 TIGRFAM: maf protein; PFAM: Maf family protein; maf protein 221028 5298442 Tmel_0214 Thermosipho melanesiensis BI429 maf protein YP_001305473.1 220480 D 391009 CDS YP_001305474.1 150020120 5298443 221029..221670 1 NC_009616.1 PFAM: helix-hairpin-helix motif; DNA repair protein RadC; DNA repair protein RadC 221670 5298443 Tmel_0215 Thermosipho melanesiensis BI429 DNA repair protein RadC YP_001305474.1 221029 D 391009 CDS YP_001305475.1 150020121 5298430 221682..222827 1 NC_009616.1 hypothetical protein 222827 5298430 Tmel_0216 Thermosipho melanesiensis BI429 hypothetical protein YP_001305475.1 221682 D 391009 CDS YP_001305476.1 150020122 5298431 222829..224235 1 NC_009616.1 hypothetical protein 224235 5298431 Tmel_0217 Thermosipho melanesiensis BI429 hypothetical protein YP_001305476.1 222829 D 391009 CDS YP_001305477.1 150020123 5298384 224232..225371 1 NC_009616.1 PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 225371 5298384 Tmel_0218 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305477.1 224232 D 391009 CDS YP_001305478.1 150020124 5298382 225382..226125 1 NC_009616.1 PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 226125 5298382 Tmel_0219 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305478.1 225382 D 391009 CDS YP_001305479.1 150020125 5298383 226109..227110 1 NC_009616.1 hypothetical protein 227110 5298383 Tmel_0220 Thermosipho melanesiensis BI429 hypothetical protein YP_001305479.1 226109 D 391009 CDS YP_001305480.1 150020126 5298347 complement(227107..229422) 1 NC_009616.1 RND efflux transporter 229422 5298347 Tmel_0221 Thermosipho melanesiensis BI429 RND efflux transporter YP_001305480.1 227107 R 391009 CDS YP_001305481.1 150020127 5298348 complement(229424..229816) 1 NC_009616.1 hypothetical protein 229816 5298348 Tmel_0222 Thermosipho melanesiensis BI429 hypothetical protein YP_001305481.1 229424 R 391009 CDS YP_001305482.1 150020128 5298345 complement(229809..230327) 1 NC_009616.1 hypothetical protein 230327 5298345 Tmel_0223 Thermosipho melanesiensis BI429 hypothetical protein YP_001305482.1 229809 R 391009 CDS YP_001305483.1 150020129 5298301 complement(230324..231529) 1 NC_009616.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; carboxyl-terminal protease 231529 5298301 Tmel_0224 Thermosipho melanesiensis BI429 carboxyl-terminal protease YP_001305483.1 230324 R 391009 CDS YP_001305484.1 150020130 5298302 complement(231522..232313) 1 NC_009616.1 PFAM: Methyltransferase type 11; tRNA methyltransferase complex GCD14 subunit; tRNA methyltransferase complex GCD14 subunit 232313 5298302 Tmel_0225 Thermosipho melanesiensis BI429 tRNA methyltransferase complex GCD14 subunit YP_001305484.1 231522 R 391009 CDS YP_001305485.1 150020131 5298285 complement(232327..232743) 1 NC_009616.1 hypothetical protein 232743 5298285 Tmel_0226 Thermosipho melanesiensis BI429 hypothetical protein YP_001305485.1 232327 R 391009 CDS YP_001305486.1 150020132 5298286 complement(232747..233433) 1 NC_009616.1 hypothetical protein 233433 5298286 Tmel_0227 Thermosipho melanesiensis BI429 hypothetical protein YP_001305486.1 232747 R 391009 CDS YP_001305487.1 150020133 5297986 complement(233430..234020) 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase 234020 5297986 Tmel_0228 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001305487.1 233430 R 391009 CDS YP_001305488.1 150020134 5298422 complement(234017..234295) 1 NC_009616.1 PFAM: protein of unknown function DUF503; hypothetical protein 234295 5298422 Tmel_0229 Thermosipho melanesiensis BI429 hypothetical protein YP_001305488.1 234017 R 391009 CDS YP_001305489.1 150020135 5298423 complement(234297..234827) 1 NC_009616.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 234827 5298423 Tmel_0230 Thermosipho melanesiensis BI429 ATP-dependent protease peptidase subunit YP_001305489.1 234297 R 391009 CDS YP_001305490.1 150020136 5298081 complement(234824..235831) 1 NC_009616.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC, N-terminal domain; Sua5/YciO/YrdC/YwlC family protein 235831 5298081 Tmel_0231 Thermosipho melanesiensis BI429 Sua5/YciO/YrdC/YwlC family protein YP_001305490.1 234824 R 391009 CDS YP_001305491.1 150020137 5298082 complement(235821..236669) 1 NC_009616.1 PFAM: phospholipase D/Transphosphatidylase; phospholipase D/transphosphatidylase 236669 5298082 Tmel_0232 Thermosipho melanesiensis BI429 phospholipase D/transphosphatidylase YP_001305491.1 235821 R 391009 CDS YP_001305492.1 150020138 5298035 complement(236656..238467) 1 NC_009616.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 238467 5298035 Tmel_0233 Thermosipho melanesiensis BI429 GTP-binding protein LepA YP_001305492.1 236656 R 391009 CDS YP_001305493.1 150020139 5298187 complement(238454..239734) 1 NC_009616.1 TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramoylalanine--D-glutamate ligase 239734 5298187 Tmel_0234 Thermosipho melanesiensis BI429 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_001305493.1 238454 R 391009 CDS YP_001305494.1 150020140 5298188 complement(239752..241041) 1 NC_009616.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 241041 5298188 Tmel_0235 Thermosipho melanesiensis BI429 tRNA (uracil-5-)-methyltransferase Gid YP_001305494.1 239752 R 391009 CDS YP_001305495.1 150020141 5298152 complement(241031..241942) 1 NC_009616.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; methionyl-tRNA formyltransferase 241942 5298152 Tmel_0236 Thermosipho melanesiensis BI429 methionyl-tRNA formyltransferase YP_001305495.1 241031 R 391009 CDS YP_001305496.1 150020142 5298153 complement(241973..242749) 1 NC_009616.1 TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; dimethyladenosine transferase 242749 5298153 Tmel_0237 Thermosipho melanesiensis BI429 dimethyladenosine transferase YP_001305496.1 241973 R 391009 CDS YP_001305497.1 150020143 5298359 complement(242746..243345) 1 NC_009616.1 hypothetical protein 243345 5298359 Tmel_0238 Thermosipho melanesiensis BI429 hypothetical protein YP_001305497.1 242746 R 391009 CDS YP_001305498.1 150020144 5298132 complement(243357..244352) 1 NC_009616.1 PFAM: MECDP-synthase; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 244352 5298132 Tmel_0239 Thermosipho melanesiensis BI429 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001305498.1 243357 R 391009 CDS YP_001305499.1 150020145 5298133 complement(244362..245354) 1 NC_009616.1 hypothetical protein 245354 5298133 Tmel_0240 Thermosipho melanesiensis BI429 hypothetical protein YP_001305499.1 244362 R 391009 CDS YP_001305500.1 150020146 5298167 complement(245366..246604) 1 NC_009616.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 246604 glgC 5298167 glgC Thermosipho melanesiensis BI429 glucose-1-phosphate adenylyltransferase YP_001305500.1 245366 R 391009 CDS YP_001305501.1 150020147 5298168 complement(246616..247731) 1 NC_009616.1 TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; glucose-1-phosphate adenylyltransferase, GlgD subunit 247731 5298168 Tmel_0242 Thermosipho melanesiensis BI429 glucose-1-phosphate adenylyltransferase, GlgD subunit YP_001305501.1 246616 R 391009 CDS YP_001305502.1 150020148 5298470 complement(247740..248465) 1 NC_009616.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 248465 5298470 Tmel_0243 Thermosipho melanesiensis BI429 deoxyribose-phosphate aldolase YP_001305502.1 247740 R 391009 CDS YP_001305503.1 150020149 5296871 complement(248462..248905) 1 NC_009616.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 248905 smpB 5296871 smpB Thermosipho melanesiensis BI429 SsrA-binding protein YP_001305503.1 248462 R 391009 CDS YP_001305504.1 150020150 5296872 complement(248916..249197) 1 NC_009616.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; glutamyl-tRNA(Gln) amidotransferase subunit C 249197 5296872 Tmel_0245 Thermosipho melanesiensis BI429 glutamyl-tRNA(Gln) amidotransferase subunit C YP_001305504.1 248916 R 391009 CDS YP_001305505.1 150020151 5296997 complement(249184..249411) 1 NC_009616.1 PFAM: carbon storage regulator; carbon storage regulator CsrA 249411 5296997 Tmel_0246 Thermosipho melanesiensis BI429 carbon storage regulator CsrA YP_001305505.1 249184 R 391009 CDS YP_001305506.1 150020152 5296998 complement(249421..249849) 1 NC_009616.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 249849 5296998 Tmel_0247 Thermosipho melanesiensis BI429 flagellar assembly protein FliW YP_001305506.1 249421 R 391009 CDS YP_001305507.1 150020153 5296860 complement(249858..250622) 1 NC_009616.1 PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 250622 5296860 Tmel_0248 Thermosipho melanesiensis BI429 alpha/beta hydrolase fold protein YP_001305507.1 249858 R 391009 CDS YP_001305508.1 150020154 5297395 complement(250624..251022) 1 NC_009616.1 PFAM: Positive regulator of sigma(E), RseC/MucC; positive regulator of sigma E, RseC/MucC 251022 5297395 Tmel_0249 Thermosipho melanesiensis BI429 positive regulator of sigma E, RseC/MucC YP_001305508.1 250624 R 391009 CDS YP_001305509.1 150020155 5297396 complement(251031..252644) 1 NC_009616.1 PFAM: Dak phosphatase; Dak phosphatase 252644 5297396 Tmel_0250 Thermosipho melanesiensis BI429 Dak phosphatase YP_001305509.1 251031 R 391009 CDS YP_001305510.1 150020156 5297505 complement(252658..252987) 1 NC_009616.1 PFAM: protein of unknown function DUF322; hypothetical protein 252987 5297505 Tmel_0251 Thermosipho melanesiensis BI429 hypothetical protein YP_001305510.1 252658 R 391009 CDS YP_001305511.1 150020157 5297506 complement(252962..254803) 1 NC_009616.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 254803 5297506 Tmel_0252 Thermosipho melanesiensis BI429 1-deoxy-D-xylulose-5-phosphate synthase YP_001305511.1 252962 R 391009 CDS YP_001305512.1 150020158 5297190 complement(254814..256091) 1 NC_009616.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 256091 5297190 Tmel_0253 Thermosipho melanesiensis BI429 seryl-tRNA synthetase YP_001305512.1 254814 R 391009 CDS YP_001305513.1 150020159 5296904 complement(256097..257137) 1 NC_009616.1 TIGRFAM: putative translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; aIF-2BI family translation initiation factor 257137 5296904 Tmel_0254 Thermosipho melanesiensis BI429 aIF-2BI family translation initiation factor YP_001305513.1 256097 R 391009 CDS YP_001305514.1 150020160 5296905 complement(257214..258200) 1 NC_009616.1 hypothetical protein 258200 5296905 Tmel_0255 Thermosipho melanesiensis BI429 hypothetical protein YP_001305514.1 257214 R 391009 CDS YP_001305515.1 150020161 5297116 complement(258214..260685) 1 NC_009616.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 260685 leuS 5297116 leuS Thermosipho melanesiensis BI429 leucyl-tRNA synthetase YP_001305515.1 258214 R 391009 CDS YP_001305516.1 150020162 5297117 260764..261444 1 NC_009616.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 261444 5297117 Tmel_0257 Thermosipho melanesiensis BI429 16S ribosomal RNA methyltransferase RsmE YP_001305516.1 260764 D 391009 CDS YP_001305517.1 150020163 5297225 261459..261818 1 NC_009616.1 hypothetical protein 261818 5297225 Tmel_0258 Thermosipho melanesiensis BI429 hypothetical protein YP_001305517.1 261459 D 391009 CDS YP_001305518.1 150020164 5296505 complement(261823..262254) 1 NC_009616.1 PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 262254 5296505 Tmel_0259 Thermosipho melanesiensis BI429 GCN5-like N-acetyltransferase YP_001305518.1 261823 R 391009 CDS YP_001305519.1 150020165 5296506 complement(262265..263755) 1 NC_009616.1 PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; peptidase M50 263755 5296506 Tmel_0260 Thermosipho melanesiensis BI429 peptidase M50 YP_001305519.1 262265 R 391009 CDS YP_001305520.1 150020166 5297228 complement(263742..265133) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; response regulator receiver modulated diguanylate cyclase 265133 5297228 Tmel_0261 Thermosipho melanesiensis BI429 response regulator receiver modulated diguanylate cyclase YP_001305520.1 263742 R 391009 CDS YP_001305521.1 150020167 5297229 complement(265126..266697) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 266697 5297229 Tmel_0262 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001305521.1 265126 R 391009 CDS YP_001305522.1 150020168 5296826 266808..267839 1 NC_009616.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 267839 ispG 5296826 ispG Thermosipho melanesiensis BI429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001305522.1 266808 D 391009 CDS YP_001305523.1 150020169 5297281 complement(267820..268851) 1 NC_009616.1 hypothetical protein 268851 5297281 Tmel_0264 Thermosipho melanesiensis BI429 hypothetical protein YP_001305523.1 267820 R 391009 CDS YP_001305524.1 150020170 5297282 269251..270180 1 NC_009616.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 270180 pyrC 5297282 pyrC Thermosipho melanesiensis BI429 dihydroorotase YP_001305524.1 269251 D 391009 CDS YP_001305525.1 150020171 5297469 270158..270802 1 NC_009616.1 2-polyprenylphenol hydroxylase-like protein 270802 5297469 Tmel_0266 Thermosipho melanesiensis BI429 2-polyprenylphenol hydroxylase-like protein YP_001305525.1 270158 D 391009 CDS YP_001305526.1 150020172 5297470 270799..271614 1 NC_009616.1 TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; dihydroorotate dehydrogenase family protein 271614 5297470 Tmel_0267 Thermosipho melanesiensis BI429 dihydroorotate dehydrogenase family protein YP_001305526.1 270799 D 391009 CDS YP_001305527.1 150020173 5297860 271611..272222 1 NC_009616.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 272222 5297860 Tmel_0268 Thermosipho melanesiensis BI429 orotidine 5'-phosphate decarboxylase YP_001305527.1 271611 D 391009 CDS YP_001305528.1 150020174 5296555 272213..272779 1 NC_009616.1 TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; orotate phosphoribosyltransferase 272779 5296555 Tmel_0269 Thermosipho melanesiensis BI429 orotate phosphoribosyltransferase YP_001305528.1 272213 D 391009 CDS YP_001305529.1 150020175 5297990 complement(277715..278974) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 278974 5297990 Tmel_0270 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305529.1 277715 R 391009 CDS YP_001305530.1 150020176 5297145 complement(279027..280148) 1 NC_009616.1 PFAM: FAD dependent oxidoreductase; FAD dependent oxidoreductase 280148 5297145 Tmel_0271 Thermosipho melanesiensis BI429 FAD dependent oxidoreductase YP_001305530.1 279027 R 391009 CDS YP_001305531.1 150020177 5297350 282388..284376 1 NC_009616.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; RNA-binding S1 domain-containing protein 284376 5297350 Tmel_0274 Thermosipho melanesiensis BI429 RNA-binding S1 domain-containing protein YP_001305531.1 282388 D 391009 CDS YP_001305532.1 150020178 5297036 284381..284833 1 NC_009616.1 PFAM: CheW domain protein; putative CheW protein 284833 5297036 Tmel_0275 Thermosipho melanesiensis BI429 putative CheW protein YP_001305532.1 284381 D 391009 CDS YP_001305533.1 150020179 5297037 complement(284826..287054) 1 NC_009616.1 TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; primosomal protein N' 287054 5297037 Tmel_0276 Thermosipho melanesiensis BI429 primosomal protein N' YP_001305533.1 284826 R 391009 CDS YP_001305534.1 150020180 5297006 287157..287366 1 NC_009616.1 TIGRFAM: putative regulatory protein, FmdB family; FmdB family regulatory protein 287366 5297006 Tmel_0277 Thermosipho melanesiensis BI429 FmdB family regulatory protein YP_001305534.1 287157 D 391009 CDS YP_001305535.1 150020181 5297007 complement(287418..287615) 1 NC_009616.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; cold-shock DNA-binding domain-containing protein 287615 5297007 Tmel_0278 Thermosipho melanesiensis BI429 cold-shock DNA-binding domain-containing protein YP_001305535.1 287418 R 391009 CDS YP_001305536.1 150020182 5296677 complement(288273..288932) 1 NC_009616.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 288932 5296677 Tmel_0279 Thermosipho melanesiensis BI429 uroporphyrin-III C/tetrapyrrole methyltransferase YP_001305536.1 288273 R 391009 CDS YP_001305537.1 150020183 5297670 complement(288920..289633) 1 NC_009616.1 PFAM: biotin/lipoate A/B protein ligase; biotin/lipoate A/B protein ligase 289633 5297670 Tmel_0280 Thermosipho melanesiensis BI429 biotin/lipoate A/B protein ligase YP_001305537.1 288920 R 391009 CDS YP_001305538.1 150020184 5297671 complement(289634..290233) 1 NC_009616.1 hypothetical protein 290233 5297671 Tmel_0281 Thermosipho melanesiensis BI429 hypothetical protein YP_001305538.1 289634 R 391009 CDS YP_001305539.1 150020185 5297155 complement(290235..291020) 1 NC_009616.1 hypothetical protein 291020 5297155 Tmel_0282 Thermosipho melanesiensis BI429 hypothetical protein YP_001305539.1 290235 R 391009 CDS YP_001305540.1 150020186 5297156 complement(291021..291215) 1 NC_009616.1 hypothetical protein 291215 5297156 Tmel_0283 Thermosipho melanesiensis BI429 hypothetical protein YP_001305540.1 291021 R 391009 CDS YP_001305541.1 150020187 5297556 complement(291215..291574) 1 NC_009616.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 291574 5297556 Tmel_0284 Thermosipho melanesiensis BI429 aspartate alpha-decarboxylase YP_001305541.1 291215 R 391009 CDS YP_001305542.1 150020188 5296526 complement(291576..294179) 1 NC_009616.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; GAF domain protein; multi-sensor signal transduction histidine kinase 294179 5296526 Tmel_0285 Thermosipho melanesiensis BI429 multi-sensor signal transduction histidine kinase YP_001305542.1 291576 R 391009 CDS YP_001305543.1 150020189 5296527 complement(294257..294787) 1 NC_009616.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; sigma 54 modulation protein/ribosomal protein S30EA 294787 5296527 Tmel_0286 Thermosipho melanesiensis BI429 sigma 54 modulation protein/ribosomal protein S30EA YP_001305543.1 294257 R 391009 CDS YP_001305544.1 150020190 5296977 complement(294799..295269) 1 NC_009616.1 hypothetical protein 295269 5296977 Tmel_0287 Thermosipho melanesiensis BI429 hypothetical protein YP_001305544.1 294799 R 391009 CDS YP_001305545.1 150020191 5296978 complement(295306..296127) 1 NC_009616.1 PFAM: DegV family protein; DegV family protein 296127 5296978 Tmel_0288 Thermosipho melanesiensis BI429 DegV family protein YP_001305545.1 295306 R 391009 CDS YP_001305546.1 150020192 5297481 complement(296132..296446) 1 NC_009616.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 296446 atpC 5297481 atpC Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit epsilon YP_001305546.1 296132 R 391009 CDS YP_001305547.1 150020193 5296886 complement(296443..297852) 1 NC_009616.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 297852 5296886 Tmel_0290 Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit beta YP_001305547.1 296443 R 391009 CDS YP_001305548.1 150020194 5296887 complement(297873..298694) 1 NC_009616.1 TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+-transporting two-sector ATPase, gamma subunit; ATP synthase F1 subunit gamma 298694 5296887 Tmel_0291 Thermosipho melanesiensis BI429 ATP synthase F1 subunit gamma YP_001305548.1 297873 R 391009 CDS YP_001305549.1 150020195 5296928 complement(298700..300223) 1 NC_009616.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 300223 5296928 Tmel_0292 Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit alpha YP_001305549.1 298700 R 391009 CDS YP_001305550.1 150020196 5296929 complement(300228..300767) 1 NC_009616.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 300767 5296929 Tmel_0293 Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit delta YP_001305550.1 300228 R 391009 CDS YP_001305551.1 150020197 5297662 complement(300764..301249) 1 NC_009616.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+-transporting two-sector ATPase, B/B' subunit; ATP synthase F0 subunit B 301249 5297662 Tmel_0294 Thermosipho melanesiensis BI429 ATP synthase F0 subunit B YP_001305551.1 300764 R 391009 CDS YP_001305552.1 150020198 5296766 complement(301264..301515) 1 NC_009616.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 301515 5296766 Tmel_0295 Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit C YP_001305552.1 301264 R 391009 CDS YP_001305553.1 150020199 5296767 complement(301530..302372) 1 NC_009616.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 302372 5296767 Tmel_0296 Thermosipho melanesiensis BI429 F0F1 ATP synthase subunit A YP_001305553.1 301530 R 391009 CDS YP_001305554.1 150020200 5296947 complement(302356..302730) 1 NC_009616.1 hypothetical protein 302730 5296947 Tmel_0297 Thermosipho melanesiensis BI429 hypothetical protein YP_001305554.1 302356 R 391009 CDS YP_001305555.1 150020201 5296948 complement(302714..302962) 1 NC_009616.1 hypothetical protein 302962 5296948 Tmel_0298 Thermosipho melanesiensis BI429 hypothetical protein YP_001305555.1 302714 R 391009 CDS YP_001305556.1 150020202 5297418 complement(302959..304026) 1 NC_009616.1 PFAM: creatinase; peptidase M24; peptidase M24 304026 5297418 Tmel_0299 Thermosipho melanesiensis BI429 peptidase M24 YP_001305556.1 302959 R 391009 CDS YP_001305557.1 150020203 5298017 complement(304125..304733) 1 NC_009616.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase, RNase H domain protein fold; Holliday junction resolvase YqgF 304733 5298017 Tmel_0300 Thermosipho melanesiensis BI429 Holliday junction resolvase YqgF YP_001305557.1 304125 R 391009 CDS YP_001305558.1 150020204 5296891 complement(304742..307675) 1 NC_009616.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; single-stranded-DNA-specific exonuclease RecJ 307675 5296891 Tmel_0301 Thermosipho melanesiensis BI429 single-stranded-DNA-specific exonuclease RecJ YP_001305558.1 304742 R 391009 CDS YP_001305559.1 150020205 5297763 308062..308925 1 NC_009616.1 PFAM: Hsp33 protein; Hsp33 protein 308925 5297763 Tmel_0302 Thermosipho melanesiensis BI429 Hsp33 protein YP_001305559.1 308062 D 391009 CDS YP_001305560.1 150020206 5297764 308922..310091 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; integral membrane sensor signal transduction histidine kinase 310091 5297764 Tmel_0303 Thermosipho melanesiensis BI429 integral membrane sensor signal transduction histidine kinase YP_001305560.1 308922 D 391009 CDS YP_001305561.1 150020207 5296808 310081..311736 1 NC_009616.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 311736 5296808 Tmel_0304 Thermosipho melanesiensis BI429 formate--tetrahydrofolate ligase YP_001305561.1 310081 D 391009 CDS YP_001305562.1 150020208 5297223 311910..313193 1 NC_009616.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Glu/Leu/Phe/Val dehydrogenase, C terminal 313193 5297223 Tmel_0305 Thermosipho melanesiensis BI429 Glu/Leu/Phe/Val dehydrogenase, C terminal YP_001305562.1 311910 D 391009 CDS YP_001305563.1 150020209 5297224 complement(313375..314154) 1 NC_009616.1 PFAM: putative RNA methylase; putative RNA methylase 314154 5297224 Tmel_0306 Thermosipho melanesiensis BI429 putative RNA methylase YP_001305563.1 313375 R 391009 CDS YP_001305564.1 150020210 5297178 complement(314157..314975) 1 NC_009616.1 PFAM: DpmII restriction endonuclease; Type II site-specific deoxyribonuclease 314975 5297178 Tmel_0307 Thermosipho melanesiensis BI429 Type II site-specific deoxyribonuclease YP_001305564.1 314157 R 391009 CDS YP_001305565.1 150020211 5297179 complement(314995..315927) 1 NC_009616.1 TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase 315927 5297179 Tmel_0308 Thermosipho melanesiensis BI429 DNA adenine methylase YP_001305565.1 314995 R 391009 CDS YP_001305566.1 150020212 5297576 complement(316122..316241) 1 NC_009616.1 hypothetical protein 316241 5297576 Tmel_0309 Thermosipho melanesiensis BI429 hypothetical protein YP_001305566.1 316122 R 391009 CDS YP_001305567.1 150020213 5297457 complement(316429..316659) 1 NC_009616.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 316659 acpP 5297457 acpP Thermosipho melanesiensis BI429 acyl carrier protein YP_001305567.1 316429 R 391009 CDS YP_001305568.1 150020214 5297458 complement(316780..318321) 1 NC_009616.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein 318321 5297458 Tmel_0311 Thermosipho melanesiensis BI429 TPR repeat-containing protein YP_001305568.1 316780 R 391009 CDS YP_001305569.1 150020215 5296609 complement(318352..318684) 1 NC_009616.1 PFAM: histidine triad (HIT) protein; histidine triad (HIT) protein 318684 5296609 Tmel_0312 Thermosipho melanesiensis BI429 histidine triad (HIT) protein YP_001305569.1 318352 R 391009 CDS YP_001305570.1 150020216 5296610 complement(318698..319897) 1 NC_009616.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 319897 5296610 Tmel_0313 Thermosipho melanesiensis BI429 adenylosuccinate synthetase YP_001305570.1 318698 R 391009 CDS YP_001305571.1 150020217 5297872 complement(319913..321172) 1 NC_009616.1 hypothetical protein 321172 5297872 Tmel_0314 Thermosipho melanesiensis BI429 hypothetical protein YP_001305571.1 319913 R 391009 CDS YP_001305572.1 150020218 5296814 complement(321174..321845) 1 NC_009616.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 321845 5296814 Tmel_0315 Thermosipho melanesiensis BI429 metal-dependent hydrolase YP_001305572.1 321174 R 391009 CDS YP_001305573.1 150020219 5296815 321960..323327 1 NC_009616.1 hypothetical protein 323327 5296815 Tmel_0316 Thermosipho melanesiensis BI429 hypothetical protein YP_001305573.1 321960 D 391009 CDS YP_001305574.1 150020220 5297040 323331..323918 1 NC_009616.1 MutT family phosphoesterase 323918 5297040 Tmel_0317 Thermosipho melanesiensis BI429 MutT family phosphoesterase YP_001305574.1 323331 D 391009 CDS YP_001305575.1 150020221 5297041 323873..324697 1 NC_009616.1 TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 324697 5297041 Tmel_0318 Thermosipho melanesiensis BI429 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_001305575.1 323873 D 391009 CDS YP_001305576.1 150020222 5296536 324678..327029 1 NC_009616.1 PFAM: peptidase S16, lon domain protein; peptidase S16, lon domain-containing protein 327029 5296536 Tmel_0319 Thermosipho melanesiensis BI429 peptidase S16, lon domain-containing protein YP_001305576.1 324678 D 391009 CDS YP_001305577.1 150020223 5296968 327034..328029 1 NC_009616.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 328029 5296968 Tmel_0320 Thermosipho melanesiensis BI429 tryptophanyl-tRNA synthetase YP_001305577.1 327034 D 391009 CDS YP_001305578.1 150020224 5296969 328035..328820 1 NC_009616.1 PFAM: MscS Mechanosensitive ion channel; mechanosensitive ion channel MscS 328820 5296969 Tmel_0321 Thermosipho melanesiensis BI429 mechanosensitive ion channel MscS YP_001305578.1 328035 D 391009 CDS YP_001305579.1 150020225 5297579 328909..330897 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 330897 5297579 Tmel_0322 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305579.1 328909 D 391009 CDS YP_001305580.1 150020226 5298012 complement(331607..331774) 1 NC_009616.1 hypothetical protein 331774 5298012 Tmel_0324 Thermosipho melanesiensis BI429 hypothetical protein YP_001305580.1 331607 R 391009 CDS YP_001305581.1 150020227 5298013 332217..332468 1 NC_009616.1 putative anti-sigma-28 factor FlgM 332468 5298013 Tmel_0326 Thermosipho melanesiensis BI429 putative anti-sigma-28 factor FlgM YP_001305581.1 332217 D 391009 CDS YP_001305582.1 150020228 5297811 332472..332903 1 NC_009616.1 hypothetical protein 332903 5297811 Tmel_0327 Thermosipho melanesiensis BI429 hypothetical protein YP_001305582.1 332472 D 391009 CDS YP_001305583.1 150020229 5297812 332915..335455 1 NC_009616.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar hook-associated protein FlgK 335455 5297812 Tmel_0328 Thermosipho melanesiensis BI429 flagellar hook-associated protein FlgK YP_001305583.1 332915 D 391009 CDS YP_001305584.1 150020230 5297114 335467..336354 1 NC_009616.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; flagellar hook-associated protein 3 336354 5297114 Tmel_0329 Thermosipho melanesiensis BI429 flagellar hook-associated protein 3 YP_001305584.1 335467 D 391009 CDS YP_001305585.1 150020231 5297115 336351..337004 1 NC_009616.1 O-methyltransferase-like protein 337004 5297115 Tmel_0330 Thermosipho melanesiensis BI429 O-methyltransferase-like protein YP_001305585.1 336351 D 391009 CDS YP_001305586.1 150020232 5297904 337037..338962 1 NC_009616.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; putative adenylate/guanylate cyclase 338962 5297904 Tmel_0331 Thermosipho melanesiensis BI429 putative adenylate/guanylate cyclase YP_001305586.1 337037 D 391009 CDS YP_001305587.1 150020233 5297739 338955..339848 1 NC_009616.1 putative metal dependent phosphohydrolase 339848 5297739 Tmel_0332 Thermosipho melanesiensis BI429 putative metal dependent phosphohydrolase YP_001305587.1 338955 D 391009 CDS YP_001305588.1 150020234 5297740 339841..340470 1 NC_009616.1 hypothetical protein 340470 5297740 Tmel_0333 Thermosipho melanesiensis BI429 hypothetical protein YP_001305588.1 339841 D 391009 CDS YP_001305589.1 150020235 5297741 340467..342461 1 NC_009616.1 hypothetical protein 342461 5297741 Tmel_0334 Thermosipho melanesiensis BI429 hypothetical protein YP_001305589.1 340467 D 391009 CDS YP_001305590.1 150020236 5297742 342466..343677 1 NC_009616.1 PFAM: GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 343677 5297742 Tmel_0335 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001305590.1 342466 D 391009 CDS YP_001305591.1 150020237 5298222 343823..344473 1 NC_009616.1 TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; L-serine dehydratase, iron-sulfur-dependent subunit beta 344473 5298222 Tmel_0336 Thermosipho melanesiensis BI429 L-serine dehydratase, iron-sulfur-dependent subunit beta YP_001305591.1 343823 D 391009 CDS YP_001305592.1 150020238 5297828 344470..345330 1 NC_009616.1 TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; L-serine dehydratase, iron-sulfur-dependent subunit alpha 345330 5297828 Tmel_0337 Thermosipho melanesiensis BI429 L-serine dehydratase, iron-sulfur-dependent subunit alpha YP_001305592.1 344470 D 391009 CDS YP_001305593.1 150020239 5297829 345452..346237 1 NC_009616.1 hypothetical protein 346237 5297829 Tmel_0338 Thermosipho melanesiensis BI429 hypothetical protein YP_001305593.1 345452 D 391009 CDS YP_001305594.1 150020240 5297981 346240..347844 1 NC_009616.1 PFAM: glycoside hydrolase, family 57; Domain of unknown function DUF1957; hypothetical protein 347844 5297981 Tmel_0339 Thermosipho melanesiensis BI429 hypothetical protein YP_001305594.1 346240 D 391009 CDS YP_001305595.1 150020241 5297982 347870..348445 1 NC_009616.1 TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase subunit gamma 348445 5297982 Tmel_0340 Thermosipho melanesiensis BI429 pyruvate/ketoisovalerate oxidoreductase subunit gamma YP_001305595.1 347870 D 391009 CDS YP_001305596.1 150020242 5296953 348438..348770 1 NC_009616.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase subunit delta 348770 5296953 Tmel_0341 Thermosipho melanesiensis BI429 pyruvate ferredoxin/flavodoxin oxidoreductase subunit delta YP_001305596.1 348438 D 391009 CDS YP_001305597.1 150020243 5296619 348784..349962 1 NC_009616.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 349962 5296619 Tmel_0342 Thermosipho melanesiensis BI429 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein YP_001305597.1 348784 D 391009 CDS YP_001305598.1 150020244 5296620 349976..350953 1 NC_009616.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein 350953 5296620 Tmel_0343 Thermosipho melanesiensis BI429 thiamine pyrophosphate binding domain-containing protein YP_001305598.1 349976 D 391009 CDS YP_001305599.1 150020245 5296599 351060..351977 1 NC_009616.1 PFAM: glycosyl transferase, family 4; glycosyl transferase family protein 351977 5296599 Tmel_0344 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305599.1 351060 D 391009 CDS YP_001305600.1 150020246 5296600 351967..352476 1 NC_009616.1 hypothetical protein 352476 5296600 Tmel_0345 Thermosipho melanesiensis BI429 hypothetical protein YP_001305600.1 351967 D 391009 CDS YP_001305601.1 150020247 5298207 complement(357995..359677) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 359677 5298207 Tmel_0346 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305601.1 357995 R 391009 CDS YP_001305602.1 150020248 5296863 complement(360707..360967) 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein 360967 5296863 Tmel_0347 Thermosipho melanesiensis BI429 CRISPR-associated Cas2 family protein YP_001305602.1 360707 R 391009 CDS YP_001305603.1 150020249 5296864 complement(360970..361965) 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; CRISPR-associated Cas1 family protein 361965 5296864 Tmel_0348 Thermosipho melanesiensis BI429 CRISPR-associated Cas1 family protein YP_001305603.1 360970 R 391009 CDS YP_001305604.1 150020250 5296642 complement(361971..362447) 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas4; PFAM: protein of unknown function DUF83; CRISPR-associated Cas4 family protein 362447 5296642 Tmel_0349 Thermosipho melanesiensis BI429 CRISPR-associated Cas4 family protein YP_001305604.1 361971 R 391009 CDS YP_001305605.1 150020251 5296643 complement(362444..362836) 1 NC_009616.1 hypothetical protein 362836 5296643 Tmel_0350 Thermosipho melanesiensis BI429 hypothetical protein YP_001305605.1 362444 R 391009 CDS YP_001305606.1 150020252 5297272 complement(362898..364853) 1 NC_009616.1 TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; CRISPR-associated helicase Cas3 364853 5297272 Tmel_0351 Thermosipho melanesiensis BI429 CRISPR-associated helicase Cas3 YP_001305606.1 362898 R 391009 CDS YP_001305607.1 150020253 5297277 complement(364831..365592) 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas5; CRISPR-associated Cas5 family protein 365592 5297277 Tmel_0352 Thermosipho melanesiensis BI429 CRISPR-associated Cas5 family protein YP_001305607.1 364831 R 391009 CDS YP_001305608.1 150020254 5297278 complement(365604..366527) 1 NC_009616.1 hypothetical protein 366527 5297278 Tmel_0353 Thermosipho melanesiensis BI429 hypothetical protein YP_001305608.1 365604 R 391009 CDS YP_001305609.1 150020255 5297348 complement(366542..368242) 1 NC_009616.1 hypothetical protein 368242 5297348 Tmel_0354 Thermosipho melanesiensis BI429 hypothetical protein YP_001305609.1 366542 R 391009 CDS YP_001305610.1 150020256 5297349 complement(368254..368982) 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated Cas family protein 368982 5297349 Tmel_0355 Thermosipho melanesiensis BI429 CRISPR-associated Cas family protein YP_001305610.1 368254 R 391009 CDS YP_001305611.1 150020257 5297380 complement(369745..369930) 1 NC_009616.1 hypothetical protein 369930 5297380 Tmel_0356 Thermosipho melanesiensis BI429 hypothetical protein YP_001305611.1 369745 R 391009 CDS YP_001305612.1 150020258 5296658 complement(370396..370557) 1 NC_009616.1 hypothetical protein 370557 5296658 Tmel_0357 Thermosipho melanesiensis BI429 hypothetical protein YP_001305612.1 370396 R 391009 CDS YP_001305613.1 150020259 5298186 complement(371265..371684) 1 NC_009616.1 hypothetical protein 371684 5298186 Tmel_0358 Thermosipho melanesiensis BI429 hypothetical protein YP_001305613.1 371265 R 391009 CDS YP_001305614.1 150020260 5296821 371773..372993 1 NC_009616.1 PFAM: peptidase M48, Ste24p; Ste24 endopeptidase 372993 5296821 Tmel_0359 Thermosipho melanesiensis BI429 Ste24 endopeptidase YP_001305614.1 371773 D 391009 CDS YP_001305615.1 150020261 5298007 373383..374831 1 NC_009616.1 PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; polysaccharide biosynthesis protein 374831 5298007 Tmel_0361 Thermosipho melanesiensis BI429 polysaccharide biosynthesis protein YP_001305615.1 373383 D 391009 CDS YP_001305616.1 150020262 5297575 374837..375943 1 NC_009616.1 hypothetical protein 375943 5297575 Tmel_0362 Thermosipho melanesiensis BI429 hypothetical protein YP_001305616.1 374837 D 391009 CDS YP_001305617.1 150020263 5297720 375959..377110 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 377110 5297720 Tmel_0363 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001305617.1 375959 D 391009 CDS YP_001305618.1 150020264 5297721 complement(377102..378277) 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 378277 5297721 Tmel_0364 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001305618.1 377102 R 391009 CDS YP_001305619.1 150020265 5297691 complement(378279..379493) 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 379493 5297691 Tmel_0365 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001305619.1 378279 R 391009 CDS YP_001305620.1 150020266 5297692 complement(379490..380551) 1 NC_009616.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 380551 5297692 Tmel_0366 Thermosipho melanesiensis BI429 UDP-N-acetylglucosamine 2-epimerase YP_001305620.1 379490 R 391009 CDS YP_001305621.1 150020267 5297234 complement(380603..384073) 1 NC_009616.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: phosphoribosyltransferase; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; ATP-dependent DNA helicase RecQ 384073 5297234 Tmel_0367 Thermosipho melanesiensis BI429 ATP-dependent DNA helicase RecQ YP_001305621.1 380603 R 391009 CDS YP_001305622.1 150020268 5297955 384089..385060 1 NC_009616.1 PFAM: SMF family protein; SMF family protein 385060 5297955 Tmel_0368 Thermosipho melanesiensis BI429 SMF family protein YP_001305622.1 384089 D 391009 CDS YP_001305623.1 150020269 5297956 complement(385047..386303) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 386303 5297956 Tmel_0369 Thermosipho melanesiensis BI429 major facilitator transporter YP_001305623.1 385047 R 391009 CDS YP_001305624.1 150020270 5296973 complement(386281..387309) 1 NC_009616.1 hypothetical protein 387309 5296973 Tmel_0370 Thermosipho melanesiensis BI429 hypothetical protein YP_001305624.1 386281 R 391009 CDS YP_001305625.1 150020271 5296974 complement(387302..387673) 1 NC_009616.1 hypothetical protein 387673 5296974 Tmel_0371 Thermosipho melanesiensis BI429 hypothetical protein YP_001305625.1 387302 R 391009 CDS YP_001305626.1 150020272 5298030 388000..389304 1 NC_009616.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 389304 obgE 5298030 obgE Thermosipho melanesiensis BI429 GTPase ObgE YP_001305626.1 388000 D 391009 CDS YP_001305627.1 150020273 5296831 389288..389881 1 NC_009616.1 TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 389881 5296831 Tmel_0373 Thermosipho melanesiensis BI429 nicotinate (nicotinamide) nucleotide adenylyltransferase YP_001305627.1 389288 D 391009 CDS YP_001305628.1 150020274 5296832 389868..390755 1 NC_009616.1 PFAM: dihydrouridine synthase, DuS; dihydrouridine synthase, DuS 390755 5296832 Tmel_0374 Thermosipho melanesiensis BI429 dihydrouridine synthase, DuS YP_001305628.1 389868 D 391009 CDS YP_001305629.1 150020275 5296675 390844..391815 1 NC_009616.1 PFAM: polysaccharide deacetylase; polysaccharide deacetylase 391815 5296675 Tmel_0375 Thermosipho melanesiensis BI429 polysaccharide deacetylase YP_001305629.1 390844 D 391009 CDS YP_001305630.1 150020276 5296676 391802..392923 1 NC_009616.1 PFAM: aminotransferase, class I and II; Allinase-like; class I and II aminotransferase 392923 5296676 Tmel_0376 Thermosipho melanesiensis BI429 class I and II aminotransferase YP_001305630.1 391802 D 391009 CDS YP_001305631.1 150020277 5297641 392954..393613 1 NC_009616.1 PFAM: 2-phosphosulfolactate phosphatase; 2-phosphosulfolactate phosphatase 393613 5297641 Tmel_0377 Thermosipho melanesiensis BI429 2-phosphosulfolactate phosphatase YP_001305631.1 392954 D 391009 CDS YP_001305632.1 150020278 5296700 393615..394493 1 NC_009616.1 hypothetical protein 394493 5296700 Tmel_0378 Thermosipho melanesiensis BI429 hypothetical protein YP_001305632.1 393615 D 391009 CDS YP_001305633.1 150020279 5296701 394490..396397 1 NC_009616.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; glycosyl transferase family protein 396397 5296701 Tmel_0379 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305633.1 394490 D 391009 CDS YP_001305634.1 150020280 5297129 396397..396930 1 NC_009616.1 hypothetical protein 396930 5297129 Tmel_0380 Thermosipho melanesiensis BI429 hypothetical protein YP_001305634.1 396397 D 391009 CDS YP_001305635.1 150020281 5297130 396906..397349 1 NC_009616.1 PFAM: nucleoside diphosphate kinase; nucleoside-diphosphate kinase 397349 5297130 Tmel_0381 Thermosipho melanesiensis BI429 nucleoside-diphosphate kinase YP_001305635.1 396906 D 391009 CDS YP_001305636.1 150020282 5296937 complement(397350..398447) 1 NC_009616.1 PFAM: ABC-2 type transporter; ABC-2 type transporter 398447 5296937 Tmel_0382 Thermosipho melanesiensis BI429 ABC-2 type transporter YP_001305636.1 397350 R 391009 CDS YP_001305637.1 150020283 5296623 complement(398452..399621) 1 NC_009616.1 hypothetical protein 399621 5296623 Tmel_0383 Thermosipho melanesiensis BI429 hypothetical protein YP_001305637.1 398452 R 391009 CDS YP_001305638.1 150020284 5296624 complement(399608..400243) 1 NC_009616.1 hypothetical protein 400243 5296624 Tmel_0384 Thermosipho melanesiensis BI429 hypothetical protein YP_001305638.1 399608 R 391009 CDS YP_001305639.1 150020285 5296752 complement(400309..401217) 1 NC_009616.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 401217 5296752 Tmel_0385 Thermosipho melanesiensis BI429 phosphoribosylaminoimidazole synthetase YP_001305639.1 400309 R 391009 CDS YP_001305640.1 150020286 5296753 complement(401214..402401) 1 NC_009616.1 TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; phosphoribosylamine--glycine ligase 402401 5296753 Tmel_0386 Thermosipho melanesiensis BI429 phosphoribosylamine--glycine ligase YP_001305640.1 401214 R 391009 CDS YP_001305641.1 150020287 5296682 complement(402411..403304) 1 NC_009616.1 PFAM: AICARFT/IMPCHase bienzyme, formylation region; phosphoribosylaminoimidazolecarboxamide formyltransferase 403304 5296682 Tmel_0387 Thermosipho melanesiensis BI429 phosphoribosylaminoimidazolecarboxamide formyltransferase YP_001305641.1 402411 R 391009 CDS YP_001305642.1 150020288 5296702 complement(403320..403877) 1 NC_009616.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; phosphoribosylglycinamide formyltransferase 403877 5296702 Tmel_0388 Thermosipho melanesiensis BI429 phosphoribosylglycinamide formyltransferase YP_001305642.1 403320 R 391009 CDS YP_001305643.1 150020289 5296703 complement(403841..405136) 1 NC_009616.1 TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; phosphoribosyltransferase; amidophosphoribosyltransferase 405136 5296703 Tmel_0389 Thermosipho melanesiensis BI429 amidophosphoribosyltransferase YP_001305643.1 403841 R 391009 CDS YP_001305644.1 150020290 5298050 complement(405601..406080) 1 NC_009616.1 hypothetical protein 406080 5298050 Tmel_0390 Thermosipho melanesiensis BI429 hypothetical protein YP_001305644.1 405601 R 391009 CDS YP_001305645.1 150020291 5297623 complement(406192..407652) 1 NC_009616.1 PFAM: Pyrrolo-quinoline quinone; Pyrrolo-quinoline quinone 407652 5297623 Tmel_0391 Thermosipho melanesiensis BI429 Pyrrolo-quinoline quinone YP_001305645.1 406192 R 391009 CDS YP_001305646.1 150020292 5296485 complement(407895..408104) 1 NC_009616.1 hypothetical protein 408104 5296485 Tmel_0392 Thermosipho melanesiensis BI429 hypothetical protein YP_001305646.1 407895 R 391009 CDS YP_001305647.1 150020293 5297861 complement(408914..411472) 1 NC_009616.1 hypothetical protein 411472 5297861 Tmel_0393 Thermosipho melanesiensis BI429 hypothetical protein YP_001305647.1 408914 R 391009 CDS YP_001305648.1 150020294 5297862 411636..412364 1 NC_009616.1 PFAM: Recombinase; recombinase 412364 5297862 Tmel_0394 Thermosipho melanesiensis BI429 recombinase YP_001305648.1 411636 D 391009 CDS YP_001305649.1 150020295 5297385 complement(412755..412943) 1 NC_009616.1 hypothetical protein 412943 5297385 Tmel_0395 Thermosipho melanesiensis BI429 hypothetical protein YP_001305649.1 412755 R 391009 CDS YP_001305650.1 150020296 5297386 complement(413032..414216) 1 NC_009616.1 PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 414216 5297386 Tmel_0396 Thermosipho melanesiensis BI429 cobyrinic acid a,c-diamide synthase YP_001305650.1 413032 R 391009 CDS YP_001305651.1 150020297 5297017 complement(414879..416363) 1 NC_009616.1 PFAM: Resolvase, N-terminal domain; Recombinase; resolvase domain-containing protein 416363 5297017 Tmel_0397 Thermosipho melanesiensis BI429 resolvase domain-containing protein YP_001305651.1 414879 R 391009 CDS YP_001305652.1 150020298 5296975 416711..417445 1 NC_009616.1 PFAM: helix-turn-helix domain protein; XRE family transcriptional regulator 417445 5296975 Tmel_0398 Thermosipho melanesiensis BI429 XRE family transcriptional regulator YP_001305652.1 416711 D 391009 CDS YP_001305653.1 150020299 5296976 417898..418233 1 NC_009616.1 hypothetical protein 418233 5296976 Tmel_0399 Thermosipho melanesiensis BI429 hypothetical protein YP_001305653.1 417898 D 391009 CDS YP_001305654.1 150020300 5297151 418316..418513 1 NC_009616.1 hypothetical protein 418513 5297151 Tmel_0400 Thermosipho melanesiensis BI429 hypothetical protein YP_001305654.1 418316 D 391009 CDS YP_001305655.1 150020301 5297152 complement(418794..419495) 1 NC_009616.1 PFAM: protein of unknown function DUF45; hypothetical protein 419495 5297152 Tmel_0401 Thermosipho melanesiensis BI429 hypothetical protein YP_001305655.1 418794 R 391009 CDS YP_001305656.1 150020302 5297837 complement(419495..422662) 1 NC_009616.1 TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like; HsdR family type I site-specific deoxyribonuclease 422662 5297837 Tmel_0402 Thermosipho melanesiensis BI429 HsdR family type I site-specific deoxyribonuclease YP_001305656.1 419495 R 391009 CDS YP_001305657.1 150020303 5297660 complement(422659..423867) 1 NC_009616.1 PFAM: restriction modification system DNA specificity domain; restriction modification system DNA specificity subunit 423867 5297660 Tmel_0403 Thermosipho melanesiensis BI429 restriction modification system DNA specificity subunit YP_001305657.1 422659 R 391009 CDS YP_001305658.1 150020304 5297661 complement(423869..424324) 1 NC_009616.1 hypothetical protein 424324 5297661 Tmel_0404 Thermosipho melanesiensis BI429 hypothetical protein YP_001305658.1 423869 R 391009 CDS YP_001305659.1 150020305 5297522 complement(424321..426720) 1 NC_009616.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; type I restriction-modification system, M subunit 426720 5297522 Tmel_0405 Thermosipho melanesiensis BI429 type I restriction-modification system, M subunit YP_001305659.1 424321 R 391009 CDS YP_001305660.1 150020306 5297523 complement(427515..428210) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 428210 5297523 Tmel_0406 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305660.1 427515 R 391009 CDS YP_001305661.1 150020307 5297440 complement(428221..429147) 1 NC_009616.1 PFAM: ABC-2 type transporter; ABC-2 type transporter 429147 5297440 Tmel_0407 Thermosipho melanesiensis BI429 ABC-2 type transporter YP_001305661.1 428221 R 391009 CDS YP_001305662.1 150020308 5297509 complement(429646..431130) 1 NC_009616.1 PFAM: peptidase S41; peptidase S41 431130 5297509 Tmel_0408 Thermosipho melanesiensis BI429 peptidase S41 YP_001305662.1 429646 R 391009 CDS YP_001305663.1 150020309 5297510 complement(431261..432580) 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 432580 5297510 Tmel_0409 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305663.1 431261 R 391009 CDS YP_001305664.1 150020310 5297732 433152..433535 1 NC_009616.1 PFAM: Transcriptional regulator IclR-like; transcriptional regulator IclR-like protein 433535 5297732 Tmel_0410 Thermosipho melanesiensis BI429 transcriptional regulator IclR-like protein YP_001305664.1 433152 D 391009 CDS YP_001305665.1 150020311 5298002 complement(434504..435082) 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 435082 5298002 Tmel_0412 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001305665.1 434504 R 391009 CDS YP_001305666.1 150020312 5297926 435264..437633 1 NC_009616.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase 437633 5297926 Tmel_0413 Thermosipho melanesiensis BI429 ATPase YP_001305666.1 435264 D 391009 CDS YP_001305667.1 150020313 5297581 437768..437926 1 NC_009616.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; rubredoxin-type Fe(Cys)4 protein 437926 5297581 Tmel_0414 Thermosipho melanesiensis BI429 rubredoxin-type Fe(Cys)4 protein YP_001305667.1 437768 D 391009 CDS YP_001305668.1 150020314 5297582 437938..438207 1 NC_009616.1 hypothetical protein 438207 5297582 Tmel_0415 Thermosipho melanesiensis BI429 hypothetical protein YP_001305668.1 437938 D 391009 CDS YP_001305669.1 150020315 5297712 complement(438235..440028) 1 NC_009616.1 PFAM: chemotaxis sensory transducer; Heme NO binding domain protein; methyl-accepting chemotaxis sensory transducer 440028 5297712 Tmel_0416 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305669.1 438235 R 391009 CDS YP_001305670.1 150020316 5297713 440076..440807 1 NC_009616.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; pseudouridine synthase 440807 5297713 Tmel_0417 Thermosipho melanesiensis BI429 pseudouridine synthase YP_001305670.1 440076 D 391009 CDS YP_001305671.1 150020317 5297061 440804..441784 1 NC_009616.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; UDP-glucose 4-epimerase 441784 5297061 Tmel_0418 Thermosipho melanesiensis BI429 UDP-glucose 4-epimerase YP_001305671.1 440804 D 391009 CDS YP_001305672.1 150020318 5296811 441771..444782 1 NC_009616.1 PFAM: UvrD/REP helicase; UvrD/REP helicase 444782 5296811 Tmel_0419 Thermosipho melanesiensis BI429 UvrD/REP helicase YP_001305672.1 441771 D 391009 CDS YP_001305673.1 150020319 5296812 444779..447679 1 NC_009616.1 hypothetical protein 447679 5296812 Tmel_0420 Thermosipho melanesiensis BI429 hypothetical protein YP_001305673.1 444779 D 391009 CDS YP_001305674.1 150020320 5297855 447821..448372 1 NC_009616.1 hypothetical protein 448372 5297855 Tmel_0421 Thermosipho melanesiensis BI429 hypothetical protein YP_001305674.1 447821 D 391009 CDS YP_001305675.1 150020321 5297856 complement(448555..448800) 1 NC_009616.1 hypothetical protein 448800 5297856 Tmel_0422 Thermosipho melanesiensis BI429 hypothetical protein YP_001305675.1 448555 R 391009 CDS YP_001305676.1 150020322 5297747 449046..450713 1 NC_009616.1 Alpha-galactosidase-like protein 450713 5297747 Tmel_0423 Thermosipho melanesiensis BI429 Alpha-galactosidase-like protein YP_001305676.1 449046 D 391009 CDS YP_001305677.1 150020323 5297304 450706..451668 1 NC_009616.1 TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase 451668 5297304 Tmel_0424 Thermosipho melanesiensis BI429 galactose-1-phosphate uridylyltransferase YP_001305677.1 450706 D 391009 CDS YP_001305678.1 150020324 5297305 451661..452716 1 NC_009616.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 452716 5297305 Tmel_0425 Thermosipho melanesiensis BI429 galactokinase YP_001305678.1 451661 D 391009 CDS YP_001305679.1 150020325 5298213 454010..454378 1 NC_009616.1 hypothetical protein 454378 5298213 Tmel_0427 Thermosipho melanesiensis BI429 hypothetical protein YP_001305679.1 454010 D 391009 CDS YP_001305680.1 150020326 5297431 454616..454759 1 NC_009616.1 hypothetical protein 454759 5297431 Tmel_0428 Thermosipho melanesiensis BI429 hypothetical protein YP_001305680.1 454616 D 391009 CDS YP_001305681.1 150020327 5296484 complement(454834..455112) 1 NC_009616.1 PFAM: histone family protein DNA-binding protein; histone family protein DNA-binding protein 455112 5296484 Tmel_0429 Thermosipho melanesiensis BI429 histone family protein DNA-binding protein YP_001305681.1 454834 R 391009 CDS YP_001305682.1 150020328 5297076 complement(455205..455678) 1 NC_009616.1 PFAM: shikimate kinase; shikimate kinase 455678 5297076 Tmel_0430 Thermosipho melanesiensis BI429 shikimate kinase YP_001305682.1 455205 R 391009 CDS YP_001305683.1 150020329 5297077 complement(455689..456087) 1 NC_009616.1 PFAM: protein of unknown function UPF0047; hypothetical protein 456087 5297077 Tmel_0431 Thermosipho melanesiensis BI429 hypothetical protein YP_001305683.1 455689 R 391009 CDS YP_001305684.1 150020330 5297408 456218..456589 1 NC_009616.1 PFAM: ferric-uptake regulator; ferric uptake regulator family protein 456589 5297408 Tmel_0432 Thermosipho melanesiensis BI429 ferric uptake regulator family protein YP_001305684.1 456218 D 391009 CDS YP_001305685.1 150020331 5297409 456586..457365 1 NC_009616.1 PFAM: periplasmic solute binding protein; periplasmic solute binding protein 457365 5297409 Tmel_0433 Thermosipho melanesiensis BI429 periplasmic solute binding protein YP_001305685.1 456586 D 391009 CDS YP_001305686.1 150020332 5297903 457358..458080 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 458080 5297903 Tmel_0434 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305686.1 457358 D 391009 CDS YP_001305687.1 150020333 5297976 458067..458855 1 NC_009616.1 PFAM: transport system permease protein; ABC-3 protein; ABC-3 protein 458855 5297976 Tmel_0435 Thermosipho melanesiensis BI429 ABC-3 protein YP_001305687.1 458067 D 391009 CDS YP_001305688.1 150020334 5297977 459010..459504 1 NC_009616.1 hypothetical protein 459504 5297977 Tmel_0436 Thermosipho melanesiensis BI429 hypothetical protein YP_001305688.1 459010 D 391009 CDS YP_001305689.1 150020335 5297484 459552..460430 1 NC_009616.1 TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; riboflavin biosynthesis protein RibF 460430 5297484 Tmel_0437 Thermosipho melanesiensis BI429 riboflavin biosynthesis protein RibF YP_001305689.1 459552 D 391009 CDS YP_001305690.1 150020336 5297485 460420..461031 1 NC_009616.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; endonuclease III 461031 5297485 Tmel_0438 Thermosipho melanesiensis BI429 endonuclease III YP_001305690.1 460420 D 391009 CDS YP_001305691.1 150020337 5297749 461028..462155 1 NC_009616.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; DegT/DnrJ/EryC1/StrS aminotransferase 462155 5297749 Tmel_0439 Thermosipho melanesiensis BI429 DegT/DnrJ/EryC1/StrS aminotransferase YP_001305691.1 461028 D 391009 CDS YP_001305692.1 150020338 5296924 462159..462353 1 NC_009616.1 hypothetical protein 462353 5296924 Tmel_0440 Thermosipho melanesiensis BI429 hypothetical protein YP_001305692.1 462159 D 391009 CDS YP_001305693.1 150020339 5296925 462385..463725 1 NC_009616.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; xanthine/uracil/vitamin C permease 463725 5296925 Tmel_0441 Thermosipho melanesiensis BI429 xanthine/uracil/vitamin C permease YP_001305693.1 462385 D 391009 CDS YP_001305694.1 150020340 5297520 463947..465629 1 NC_009616.1 hypothetical protein 465629 5297520 Tmel_0442 Thermosipho melanesiensis BI429 hypothetical protein YP_001305694.1 463947 D 391009 CDS YP_001305695.1 150020341 5297521 465641..466027 1 NC_009616.1 hypothetical protein 466027 5297521 Tmel_0443 Thermosipho melanesiensis BI429 hypothetical protein YP_001305695.1 465641 D 391009 CDS YP_001305696.1 150020342 5297705 466029..466481 1 NC_009616.1 hypothetical protein 466481 5297705 Tmel_0444 Thermosipho melanesiensis BI429 hypothetical protein YP_001305696.1 466029 D 391009 CDS YP_001305697.1 150020343 5297938 complement(466515..467303) 1 NC_009616.1 hypothetical protein 467303 5297938 Tmel_0445 Thermosipho melanesiensis BI429 hypothetical protein YP_001305697.1 466515 R 391009 CDS YP_001305698.1 150020344 5297939 complement(467309..470521) 1 NC_009616.1 PFAM: O-antigen polymerase; O-antigen polymerase 470521 5297939 Tmel_0446 Thermosipho melanesiensis BI429 O-antigen polymerase YP_001305698.1 467309 R 391009 CDS YP_001305699.1 150020345 5297500 470602..471798 1 NC_009616.1 hypothetical protein 471798 5297500 Tmel_0447 Thermosipho melanesiensis BI429 hypothetical protein YP_001305699.1 470602 D 391009 CDS YP_001305700.1 150020346 5297501 471792..473558 1 NC_009616.1 hypothetical protein 473558 5297501 Tmel_0448 Thermosipho melanesiensis BI429 hypothetical protein YP_001305700.1 471792 D 391009 CDS YP_001305701.1 150020347 5297669 473594..474778 1 NC_009616.1 hypothetical protein 474778 5297669 Tmel_0449 Thermosipho melanesiensis BI429 hypothetical protein YP_001305701.1 473594 D 391009 CDS YP_001305702.1 150020348 5296532 474790..476820 1 NC_009616.1 hypothetical protein 476820 5296532 Tmel_0450 Thermosipho melanesiensis BI429 hypothetical protein YP_001305702.1 474790 D 391009 CDS YP_001305703.1 150020349 5296533 complement(476842..477540) 1 NC_009616.1 PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 477540 5296533 Tmel_0451 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305703.1 476842 R 391009 CDS YP_001305704.1 150020350 5297315 complement(477733..478230) 1 NC_009616.1 hypothetical protein 478230 5297315 Tmel_0452 Thermosipho melanesiensis BI429 hypothetical protein YP_001305704.1 477733 R 391009 CDS YP_001305705.1 150020351 5297316 complement(478227..478649) 1 NC_009616.1 hypothetical protein 478649 5297316 Tmel_0453 Thermosipho melanesiensis BI429 hypothetical protein YP_001305705.1 478227 R 391009 CDS YP_001305706.1 150020352 5298239 478747..479607 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 479607 5298239 Tmel_0454 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305706.1 478747 D 391009 CDS YP_001305707.1 150020353 5297745 479613..480410 1 NC_009616.1 hypothetical protein 480410 5297745 Tmel_0455 Thermosipho melanesiensis BI429 hypothetical protein YP_001305707.1 479613 D 391009 CDS YP_001305708.1 150020354 5297746 480425..481219 1 NC_009616.1 hypothetical protein 481219 5297746 Tmel_0456 Thermosipho melanesiensis BI429 hypothetical protein YP_001305708.1 480425 D 391009 CDS YP_001305709.1 150020355 5297498 481231..481800 1 NC_009616.1 PFAM: regulatory protein, TetR; TetR family transcriptional regulator 481800 5297498 Tmel_0457 Thermosipho melanesiensis BI429 TetR family transcriptional regulator YP_001305709.1 481231 D 391009 CDS YP_001305710.1 150020356 5297499 481856..483847 1 NC_009616.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 483847 5297499 Tmel_0458 Thermosipho melanesiensis BI429 alpha amylase catalytic subunit YP_001305710.1 481856 D 391009 CDS YP_001305711.1 150020357 5297863 483861..486389 1 NC_009616.1 TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase, family 13 domain protein; pullanase-associated protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; pullulanase, type I 486389 5297863 Tmel_0459 Thermosipho melanesiensis BI429 pullulanase, type I YP_001305711.1 483861 D 391009 CDS YP_001305712.1 150020358 5297672 486433..486792 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 486792 5297672 Tmel_0460 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001305712.1 486433 D 391009 CDS YP_001305713.1 150020359 5297673 486876..489602 1 NC_009616.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 489602 ileS 5297673 ileS Thermosipho melanesiensis BI429 isoleucyl-tRNA synthetase YP_001305713.1 486876 D 391009 CDS YP_001305714.1 150020360 5297610 489640..490140 1 NC_009616.1 PFAM: conserved hypothetical protein 730; hypothetical protein 490140 5297610 Tmel_0462 Thermosipho melanesiensis BI429 hypothetical protein YP_001305714.1 489640 D 391009 CDS YP_001305715.1 150020361 5297611 490137..491006 1 NC_009616.1 PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 491006 5297611 Tmel_0463 Thermosipho melanesiensis BI429 hypothetical protein YP_001305715.1 490137 D 391009 CDS YP_001305716.1 150020362 5297927 490993..492000 1 NC_009616.1 TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; rod shape-determining protein MreB 492000 5297927 Tmel_0464 Thermosipho melanesiensis BI429 rod shape-determining protein MreB YP_001305716.1 490993 D 391009 CDS YP_001305717.1 150020363 5298462 492010..492711 1 NC_009616.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; hypothetical protein 492711 5298462 Tmel_0465 Thermosipho melanesiensis BI429 hypothetical protein YP_001305717.1 492010 D 391009 CDS YP_001305718.1 150020364 5298463 492725..493510 1 NC_009616.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal-body rod protein FlgG 493510 5298463 Tmel_0466 Thermosipho melanesiensis BI429 flagellar basal-body rod protein FlgG YP_001305718.1 492725 D 391009 CDS YP_001305719.1 150020365 5297907 493600..495144 1 NC_009616.1 PFAM: protein of unknown function DUF1703; hypothetical protein 495144 5297907 Tmel_0467 Thermosipho melanesiensis BI429 hypothetical protein YP_001305719.1 493600 D 391009 CDS YP_001305720.1 150020366 5297908 complement(495175..495897) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 495897 5297908 Tmel_0468 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305720.1 495175 R 391009 CDS YP_001305721.1 150020367 5297439 complement(495894..496544) 1 NC_009616.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; Ectoine/hydroxyectoine ABC transporter, permease protein EhuC; PFAM: binding-protein-dependent transport systems inner membrane component; ectoine/hydroxyectoine ABC transporter permease EhuC 496544 5297439 Tmel_0469 Thermosipho melanesiensis BI429 ectoine/hydroxyectoine ABC transporter permease EhuC YP_001305721.1 495894 R 391009 CDS YP_001305722.1 150020368 5297034 complement(496557..497300) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; extracellular solute-binding protein 497300 5297034 Tmel_0470 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305722.1 496557 R 391009 CDS YP_001305723.1 150020369 5297035 complement(497397..499202) 1 NC_009616.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 499202 5297035 Tmel_0471 Thermosipho melanesiensis BI429 glucosamine--fructose-6-phosphate aminotransferase YP_001305723.1 497397 R 391009 CDS YP_001305724.1 150020370 5297667 complement(499171..500172) 1 NC_009616.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 500172 5297667 Tmel_0472 Thermosipho melanesiensis BI429 putative glycerol-3-phosphate acyltransferase PlsX YP_001305724.1 499171 R 391009 CDS YP_001305725.1 150020371 5297668 complement(500175..500357) 1 NC_009616.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 500357 rpmF 5297668 rpmF Thermosipho melanesiensis BI429 50S ribosomal protein L32 YP_001305725.1 500175 R 391009 CDS YP_001305726.1 150020372 5297128 complement(500376..500924) 1 NC_009616.1 PFAM: protein of unknown function DUF177; hypothetical protein 500924 5297128 Tmel_0474 Thermosipho melanesiensis BI429 hypothetical protein YP_001305726.1 500376 R 391009 CDS YP_001305727.1 150020373 5298211 500973..501926 1 NC_009616.1 PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase 501926 5298211 Tmel_0475 Thermosipho melanesiensis BI429 lytic transglycosylase YP_001305727.1 500973 D 391009 CDS YP_001305728.1 150020374 5298212 502073..503542 1 NC_009616.1 TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring C-terminal domain protein; flagellar M-ring protein FliF 503542 5298212 Tmel_0476 Thermosipho melanesiensis BI429 flagellar M-ring protein FliF YP_001305728.1 502073 D 391009 CDS YP_001305729.1 150020375 5297789 503549..504559 1 NC_009616.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 504559 fliG 5297789 fliG Thermosipho melanesiensis BI429 flagellar motor switch protein G YP_001305729.1 503549 D 391009 CDS YP_001305730.1 150020376 5297790 504570..505124 1 NC_009616.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; DNA polymerase III subunit epsilon 505124 5297790 Tmel_0478 Thermosipho melanesiensis BI429 DNA polymerase III subunit epsilon YP_001305730.1 504570 D 391009 CDS YP_001305731.1 150020377 5297871 505124..506356 1 NC_009616.1 PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; PhoH family protein 506356 5297871 Tmel_0479 Thermosipho melanesiensis BI429 PhoH family protein YP_001305731.1 505124 D 391009 CDS YP_001305732.1 150020378 5298277 506372..506923 1 NC_009616.1 hypothetical protein 506923 5298277 Tmel_0480 Thermosipho melanesiensis BI429 hypothetical protein YP_001305732.1 506372 D 391009 CDS YP_001305733.1 150020379 5298278 506917..509373 1 NC_009616.1 hypothetical protein 509373 5298278 Tmel_0481 Thermosipho melanesiensis BI429 hypothetical protein YP_001305733.1 506917 D 391009 CDS YP_001305734.1 150020380 5298299 509375..510076 1 NC_009616.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 510076 pyrH 5298299 pyrH Thermosipho melanesiensis BI429 uridylate kinase YP_001305734.1 509375 D 391009 CDS YP_001305735.1 150020381 5298300 510077..510853 1 NC_009616.1 PFAM: GTP-binding protein, HSR1-related; HSR1-like GTP-binding protein 510853 5298300 Tmel_0483 Thermosipho melanesiensis BI429 HSR1-like GTP-binding protein YP_001305735.1 510077 D 391009 CDS YP_001305736.1 150020382 5298014 510838..511305 1 NC_009616.1 PFAM: CheC domain protein; CheC domain-containing protein 511305 5298014 Tmel_0484 Thermosipho melanesiensis BI429 CheC domain-containing protein YP_001305736.1 510838 D 391009 CDS YP_001305737.1 150020383 5298235 511306..511959 1 NC_009616.1 PFAM: purine or other phosphorylase, family 1; adenosylhomocysteine nucleosidase 511959 5298235 Tmel_0485 Thermosipho melanesiensis BI429 adenosylhomocysteine nucleosidase YP_001305737.1 511306 D 391009 CDS YP_001305738.1 150020384 5298236 511969..513054 1 NC_009616.1 TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; D-alanine--D-alanine ligase 513054 5298236 Tmel_0486 Thermosipho melanesiensis BI429 D-alanine--D-alanine ligase YP_001305738.1 511969 D 391009 CDS YP_001305739.1 150020385 5298165 513051..513773 1 NC_009616.1 PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 513773 5298165 Tmel_0487 Thermosipho melanesiensis BI429 alpha/beta hydrolase fold protein YP_001305739.1 513051 D 391009 CDS YP_001305740.1 150020386 5298166 513775..515310 1 NC_009616.1 PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; Mur ligase middle domain-containing protein 515310 5298166 Tmel_0488 Thermosipho melanesiensis BI429 Mur ligase middle domain-containing protein YP_001305740.1 513775 D 391009 CDS YP_001305741.1 150020387 5298108 complement(515360..515989) 1 NC_009616.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 515989 5298108 Tmel_0489 Thermosipho melanesiensis BI429 redox-sensing transcriptional repressor Rex YP_001305741.1 515360 R 391009 CDS YP_001305742.1 150020388 5298061 complement(515973..517934) 1 NC_009616.1 PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; hydrogenase large subunit 517934 5298061 Tmel_0490 Thermosipho melanesiensis BI429 hydrogenase large subunit YP_001305742.1 515973 R 391009 CDS YP_001305743.1 150020389 5298062 complement(517947..519818) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) 519818 5298062 Tmel_0491 Thermosipho melanesiensis BI429 NADH dehydrogenase (quinone) YP_001305743.1 517947 R 391009 CDS YP_001305744.1 150020390 5298385 complement(519820..520293) 1 NC_009616.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit 520293 5298385 Tmel_0492 Thermosipho melanesiensis BI429 NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001305744.1 519820 R 391009 CDS YP_001305745.1 150020391 5298386 complement(520306..521445) 1 NC_009616.1 PFAM: Stage II sporulation E family protein; stage II sporulation E family protein 521445 5298386 Tmel_0493 Thermosipho melanesiensis BI429 stage II sporulation E family protein YP_001305745.1 520306 R 391009 CDS YP_001305746.1 150020392 5298308 complement(521447..523006) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 523006 5298308 Tmel_0494 Thermosipho melanesiensis BI429 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_001305746.1 521447 R 391009 CDS YP_001305747.1 150020393 5298294 complement(523012..523236) 1 NC_009616.1 NADH:ubiquinone oxidoreductase 24 kD subunit-like protein 523236 5298294 Tmel_0495 Thermosipho melanesiensis BI429 NADH:ubiquinone oxidoreductase 24 kD subunit-like protein YP_001305747.1 523012 R 391009 CDS YP_001305748.1 150020394 5298295 523356..523622 1 NC_009616.1 hypothetical protein 523622 5298295 Tmel_0496 Thermosipho melanesiensis BI429 hypothetical protein YP_001305748.1 523356 D 391009 CDS YP_001305749.1 150020395 5298242 complement(523833..525131) 1 NC_009616.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; response regulator receiver modulated metal dependent phosphohydrolase 525131 5298242 Tmel_0497 Thermosipho melanesiensis BI429 response regulator receiver modulated metal dependent phosphohydrolase YP_001305749.1 523833 R 391009 CDS YP_001305750.1 150020396 5298243 complement(525124..526323) 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; integral membrane sensor signal transduction histidine kinase 526323 5298243 Tmel_0498 Thermosipho melanesiensis BI429 integral membrane sensor signal transduction histidine kinase YP_001305750.1 525124 R 391009 CDS YP_001305751.1 150020397 5298353 complement(526316..527689) 1 NC_009616.1 SMART: extracellular solute-binding protein, family 3; extracellular solute-binding protein 527689 5298353 Tmel_0499 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305751.1 526316 R 391009 CDS YP_001305752.1 150020398 5298197 complement(527778..528917) 1 NC_009616.1 PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase 528917 5298197 Tmel_0500 Thermosipho melanesiensis BI429 amidohydrolase YP_001305752.1 527778 R 391009 CDS YP_001305753.1 150020399 5298198 complement(528996..533945) 1 NC_009616.1 TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 4; SMART: RNA polymerase I subunit A domain protein; DNA-directed RNA polymerase subunit beta' 533945 5298198 Tmel_0501 Thermosipho melanesiensis BI429 DNA-directed RNA polymerase subunit beta' YP_001305753.1 528996 R 391009 CDS YP_001305754.1 150020400 5298409 complement(533965..537483) 1 NC_009616.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 537483 rpoB 5298409 rpoB Thermosipho melanesiensis BI429 DNA-directed RNA polymerase subunit beta YP_001305754.1 533965 R 391009 CDS YP_001305755.1 150020401 5298410 complement(537619..538008) 1 NC_009616.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 538008 rplL 5298410 rplL Thermosipho melanesiensis BI429 50S ribosomal protein L7/L12 YP_001305755.1 537619 R 391009 CDS YP_001305756.1 150020402 5298358 complement(538026..538568) 1 NC_009616.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 538568 5298358 Tmel_0504 Thermosipho melanesiensis BI429 50S ribosomal protein L10 YP_001305756.1 538026 R 391009 CDS YP_001305757.1 150020403 5298380 539155..539784 1 NC_009616.1 PFAM: WbqC-like protein family; WbqC-like family protein 539784 5298380 Tmel_0505 Thermosipho melanesiensis BI429 WbqC-like family protein YP_001305757.1 539155 D 391009 CDS YP_001305758.1 150020404 5298381 539813..540772 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 540772 5298381 Tmel_0506 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305758.1 539813 D 391009 CDS YP_001305759.1 150020405 5298271 540769..541767 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 541767 5298271 Tmel_0507 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305759.1 540769 D 391009 CDS YP_001305760.1 150020406 5298272 541769..543649 1 NC_009616.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; asparagine synthase 543649 5298272 Tmel_0508 Thermosipho melanesiensis BI429 asparagine synthase YP_001305760.1 541769 D 391009 CDS YP_001305761.1 150020407 5298159 543662..544801 1 NC_009616.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 544801 5298159 Tmel_0509 Thermosipho melanesiensis BI429 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_001305761.1 543662 D 391009 CDS YP_001305762.1 150020408 5298305 544805..545461 1 NC_009616.1 PFAM: formyl transferase domain protein; formyl transferase domain-containing protein 545461 5298305 Tmel_0510 Thermosipho melanesiensis BI429 formyl transferase domain-containing protein YP_001305762.1 544805 D 391009 CDS YP_001305763.1 150020409 5298306 545479..546351 1 NC_009616.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidylyltransferase 546351 5298306 Tmel_0511 Thermosipho melanesiensis BI429 glucose-1-phosphate thymidylyltransferase YP_001305763.1 545479 D 391009 CDS YP_001305764.1 150020410 5298015 546365..547384 1 NC_009616.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; dTDP-glucose 4,6-dehydratase 547384 5298015 Tmel_0512 Thermosipho melanesiensis BI429 dTDP-glucose 4,6-dehydratase YP_001305764.1 546365 D 391009 CDS YP_001305765.1 150020411 5298016 547428..550202 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 550202 5298016 Tmel_0513 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001305765.1 547428 D 391009 CDS YP_001305766.1 150020412 5298180 complement(550245..551405) 1 NC_009616.1 PFAM: flagellin domain protein; flagellin domain-containing protein 551405 5298180 Tmel_0514 Thermosipho melanesiensis BI429 flagellin domain-containing protein YP_001305766.1 550245 R 391009 CDS YP_001305767.1 150020413 5298395 complement(551484..554057) 1 NC_009616.1 PFAM: glycosyl transferase, family 2; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; glycosyl transferase family protein 554057 5298395 Tmel_0515 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305767.1 551484 R 391009 CDS YP_001305768.1 150020414 5298396 complement(554062..554541) 1 NC_009616.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 554541 coaD 5298396 coaD Thermosipho melanesiensis BI429 phosphopantetheine adenylyltransferase YP_001305768.1 554062 R 391009 CDS YP_001305769.1 150020415 5298257 complement(554545..555882) 1 NC_009616.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase; replicative DNA helicase 555882 5298257 Tmel_0517 Thermosipho melanesiensis BI429 replicative DNA helicase YP_001305769.1 554545 R 391009 CDS YP_001305770.1 150020416 5298258 complement(556173..557345) 1 NC_009616.1 RecB family-like nuclease 557345 5298258 Tmel_0518 Thermosipho melanesiensis BI429 RecB family-like nuclease YP_001305770.1 556173 R 391009 CDS YP_001305771.1 150020417 5298238 557451..558995 1 NC_009616.1 PFAM: protein of unknown function DUF1703; hypothetical protein 558995 5298238 Tmel_0519 Thermosipho melanesiensis BI429 hypothetical protein YP_001305771.1 557451 D 391009 CDS YP_001305772.1 150020418 5298400 559013..560566 1 NC_009616.1 PFAM: protein of unknown function DUF1703; hypothetical protein 560566 5298400 Tmel_0520 Thermosipho melanesiensis BI429 hypothetical protein YP_001305772.1 559013 D 391009 CDS YP_001305773.1 150020419 5298401 560569..560940 1 NC_009616.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; putative endoribonuclease L-PSP 560940 5298401 Tmel_0521 Thermosipho melanesiensis BI429 putative endoribonuclease L-PSP YP_001305773.1 560569 D 391009 CDS YP_001305774.1 150020420 5298424 560943..561593 1 NC_009616.1 PFAM: helix-hairpin-helix motif; HhH-GPD family protein; HhH-GPD family protein 561593 5298424 Tmel_0522 Thermosipho melanesiensis BI429 HhH-GPD family protein YP_001305774.1 560943 D 391009 CDS YP_001305775.1 150020421 5298425 complement(561563..562813) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 562813 5298425 Tmel_0523 Thermosipho melanesiensis BI429 major facilitator transporter YP_001305775.1 561563 R 391009 CDS YP_001305776.1 150020422 5298204 562908..563288 1 NC_009616.1 TIGRFAM: methylglyoxal synthase; PFAM: MGS domain protein; methylglyoxal synthase 563288 5298204 Tmel_0524 Thermosipho melanesiensis BI429 methylglyoxal synthase YP_001305776.1 562908 D 391009 CDS YP_001305777.1 150020423 5298111 563293..564090 1 NC_009616.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3; Cof-like hydrolase 564090 5298111 Tmel_0525 Thermosipho melanesiensis BI429 Cof-like hydrolase YP_001305777.1 563293 D 391009 CDS YP_001305778.1 150020424 5298112 564038..564745 1 NC_009616.1 hypothetical protein 564745 5298112 Tmel_0526 Thermosipho melanesiensis BI429 hypothetical protein YP_001305778.1 564038 D 391009 CDS YP_001305779.1 150020425 5298093 564764..566059 1 NC_009616.1 TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; asparaginyl-tRNA synthetase 566059 5298093 Tmel_0527 Thermosipho melanesiensis BI429 asparaginyl-tRNA synthetase YP_001305779.1 564764 D 391009 CDS YP_001305780.1 150020426 5298094 complement(566130..567605) 1 NC_009616.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase; carboxypeptidase Taq 567605 5298094 Tmel_0528 Thermosipho melanesiensis BI429 carboxypeptidase Taq YP_001305780.1 566130 R 391009 CDS YP_001305781.1 150020427 5298058 complement(567621..568454) 1 NC_009616.1 PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 568454 5298058 Tmel_0529 Thermosipho melanesiensis BI429 GCN5-like N-acetyltransferase YP_001305781.1 567621 R 391009 CDS YP_001305782.1 150020428 5298113 complement(568435..568773) 1 NC_009616.1 PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; ribosomal protein L7Ae/L30e/S12e/Gadd45 568773 5298113 Tmel_0530 Thermosipho melanesiensis BI429 ribosomal protein L7Ae/L30e/S12e/Gadd45 YP_001305782.1 568435 R 391009 CDS YP_001305783.1 150020429 5298114 complement(568776..569555) 1 NC_009616.1 PFAM: protein of unknown function DUF198; hypothetical protein 569555 5298114 Tmel_0531 Thermosipho melanesiensis BI429 hypothetical protein YP_001305783.1 568776 R 391009 CDS YP_001305784.1 150020430 5298117 complement(569558..569767) 1 NC_009616.1 hypothetical protein 569767 5298117 Tmel_0532 Thermosipho melanesiensis BI429 hypothetical protein YP_001305784.1 569558 R 391009 CDS YP_001305785.1 150020431 5298118 complement(569772..571043) 1 NC_009616.1 PFAM: glycosyl transferase, group 1; sucrose synthase 571043 5298118 Tmel_0533 Thermosipho melanesiensis BI429 sucrose synthase YP_001305785.1 569772 R 391009 CDS YP_001305786.1 150020432 5298151 complement(571024..571905) 1 NC_009616.1 PFAM: PfkB domain protein; ribokinase-like domain-containing protein 571905 5298151 Tmel_0534 Thermosipho melanesiensis BI429 ribokinase-like domain-containing protein YP_001305786.1 571024 R 391009 CDS YP_001305787.1 150020433 5297853 571980..573080 1 NC_009616.1 TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; DNA polymerase III subunit beta 573080 5297853 Tmel_0535 Thermosipho melanesiensis BI429 DNA polymerase III subunit beta YP_001305787.1 571980 D 391009 CDS YP_001305788.1 150020434 5297854 573094..573513 1 NC_009616.1 hypothetical protein 573513 5297854 Tmel_0536 Thermosipho melanesiensis BI429 hypothetical protein YP_001305788.1 573094 D 391009 CDS YP_001305789.1 150020435 5297784 573510..574280 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 574280 5297784 Tmel_0537 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305789.1 573510 D 391009 CDS YP_001305790.1 150020436 5297785 574273..574674 1 NC_009616.1 hypothetical protein 574674 5297785 Tmel_0538 Thermosipho melanesiensis BI429 hypothetical protein YP_001305790.1 574273 D 391009 CDS YP_001305791.1 150020437 5297314 complement(574699..575862) 1 NC_009616.1 PFAM: flagellin domain protein; flagellin domain-containing protein 575862 5297314 Tmel_0539 Thermosipho melanesiensis BI429 flagellin domain-containing protein YP_001305791.1 574699 R 391009 CDS YP_001305792.1 150020438 5298038 575979..576959 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 576959 5298038 Tmel_0540 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305792.1 575979 D 391009 CDS YP_001305793.1 150020439 5298039 576956..577987 1 NC_009616.1 PFAM: ApbE family lipoprotein; ApbE family lipoprotein 577987 5298039 Tmel_0541 Thermosipho melanesiensis BI429 ApbE family lipoprotein YP_001305793.1 576956 D 391009 CDS YP_001305794.1 150020440 5296771 578000..578335 1 NC_009616.1 PFAM: conserved hypothetical protein 103; hypothetical protein 578335 5296771 Tmel_0542 Thermosipho melanesiensis BI429 hypothetical protein YP_001305794.1 578000 D 391009 CDS YP_001305795.1 150020441 5296772 578344..579015 1 NC_009616.1 PFAM: Rhomboid family protein; rhomboid family protein 579015 5296772 Tmel_0543 Thermosipho melanesiensis BI429 rhomboid family protein YP_001305795.1 578344 D 391009 CDS YP_001305796.1 150020442 5297655 579012..580052 1 NC_009616.1 hypothetical protein 580052 5297655 Tmel_0544 Thermosipho melanesiensis BI429 hypothetical protein YP_001305796.1 579012 D 391009 CDS YP_001305797.1 150020443 5296559 complement(580070..580597) 1 NC_009616.1 hypothetical protein 580597 5296559 Tmel_0545 Thermosipho melanesiensis BI429 hypothetical protein YP_001305797.1 580070 R 391009 CDS YP_001305798.1 150020444 5296560 580751..581998 1 NC_009616.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 581998 5296560 Tmel_0546 Thermosipho melanesiensis BI429 ErfK/YbiS/YcfS/YnhG family protein YP_001305798.1 580751 D 391009 CDS YP_001305799.1 150020445 5296726 582000..582620 1 NC_009616.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 582620 5296726 Tmel_0547 Thermosipho melanesiensis BI429 short-chain dehydrogenase/reductase SDR YP_001305799.1 582000 D 391009 CDS YP_001305800.1 150020446 5296727 complement(582593..584782) 1 NC_009616.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; glycogen debranching protein GlgX 584782 5296727 Tmel_0548 Thermosipho melanesiensis BI429 glycogen debranching protein GlgX YP_001305800.1 582593 R 391009 CDS YP_001305801.1 150020447 5296586 complement(584784..585227) 1 NC_009616.1 PFAM: OsmC family protein; OsmC family protein 585227 5296586 Tmel_0549 Thermosipho melanesiensis BI429 OsmC family protein YP_001305801.1 584784 R 391009 CDS YP_001305802.1 150020448 5296584 complement(585224..585862) 1 NC_009616.1 PFAM: cytochrome c biogenesis protein, transmembrane region; cytochrome c biogenesis protein, transmembrane region 585862 5296584 Tmel_0550 Thermosipho melanesiensis BI429 cytochrome c biogenesis protein, transmembrane region YP_001305802.1 585224 R 391009 CDS YP_001305803.1 150020449 5296585 complement(585867..586538) 1 NC_009616.1 thioredoxin-like protein 586538 5296585 Tmel_0551 Thermosipho melanesiensis BI429 thioredoxin-like protein YP_001305803.1 585867 R 391009 CDS YP_001305804.1 150020450 5296521 complement(586675..586917) 1 NC_009616.1 TIGRFAM: glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin; glutaredoxin 2; YruB family glutaredoxin-like protein 586917 5296521 Tmel_0552 Thermosipho melanesiensis BI429 YruB family glutaredoxin-like protein YP_001305804.1 586675 R 391009 CDS YP_001305805.1 150020451 5296522 complement(586930..587880) 1 NC_009616.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase 587880 5296522 Tmel_0553 Thermosipho melanesiensis BI429 thioredoxin reductase YP_001305805.1 586930 R 391009 CDS YP_001305806.1 150020452 5297497 complement(587892..588554) 1 NC_009616.1 TIGRFAM: glutaredoxin-like domain protein; glutaredoxin-like domain-containing protein 588554 5297497 Tmel_0554 Thermosipho melanesiensis BI429 glutaredoxin-like domain-containing protein YP_001305806.1 587892 R 391009 CDS YP_001305807.1 150020453 5298214 588883..589416 1 NC_009616.1 PFAM: NUDIX hydrolase; NUDIX hydrolase 589416 5298214 Tmel_0555 Thermosipho melanesiensis BI429 NUDIX hydrolase YP_001305807.1 588883 D 391009 CDS YP_001305808.1 150020454 5297496 589418..590017 1 NC_009616.1 hypothetical protein 590017 5297496 Tmel_0556 Thermosipho melanesiensis BI429 hypothetical protein YP_001305808.1 589418 D 391009 CDS YP_001305809.1 150020455 5297416 590031..590441 1 NC_009616.1 PFAM: flagellar protein FliS; flagellar protein FliS 590441 5297416 Tmel_0557 Thermosipho melanesiensis BI429 flagellar protein FliS YP_001305809.1 590031 D 391009 CDS YP_001305810.1 150020456 5297417 590454..590654 1 NC_009616.1 hypothetical protein 590654 5297417 Tmel_0558 Thermosipho melanesiensis BI429 hypothetical protein YP_001305810.1 590454 D 391009 CDS YP_001305811.1 150020457 5297629 complement(590678..591910) 1 NC_009616.1 PFAM: uncharacterised conserved protein UCP033563; hypothetical protein 591910 5297629 Tmel_0559 Thermosipho melanesiensis BI429 hypothetical protein YP_001305811.1 590678 R 391009 CDS YP_001305812.1 150020458 5296652 complement(592068..593072) 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 593072 5296652 Tmel_0560 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001305812.1 592068 R 391009 CDS YP_001305813.1 150020459 5296653 complement(593053..594057) 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 594057 5296653 Tmel_0561 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001305813.1 593053 R 391009 CDS YP_001305814.1 150020460 5297770 complement(594064..596586) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 596586 5297770 Tmel_0562 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305814.1 594064 R 391009 CDS YP_001305815.1 150020461 5297771 complement(596600..598033) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 598033 5297771 Tmel_0563 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305815.1 596600 R 391009 CDS YP_001305816.1 150020462 5296571 complement(598091..599914) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 599914 5296571 Tmel_0564 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305816.1 598091 R 391009 CDS YP_001305817.1 150020463 5297273 600064..600618 1 NC_009616.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; putative methyltransferase 600618 5297273 Tmel_0565 Thermosipho melanesiensis BI429 putative methyltransferase YP_001305817.1 600064 D 391009 CDS YP_001305818.1 150020464 5297274 complement(600586..601356) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; ornithine carbamoyltransferase 601356 5297274 Tmel_0566 Thermosipho melanesiensis BI429 ornithine carbamoyltransferase YP_001305818.1 600586 R 391009 CDS YP_001305819.1 150020465 5297300 complement(601353..602162) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 602162 5297300 Tmel_0567 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305819.1 601353 R 391009 CDS YP_001305820.1 150020466 5297301 complement(602162..603253) 1 NC_009616.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein 603253 5297301 Tmel_0568 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305820.1 602162 R 391009 CDS YP_001305821.1 150020467 5297646 complement(603265..604287) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 604287 5297646 Tmel_0569 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305821.1 603265 R 391009 CDS YP_001305822.1 150020468 5296567 complement(604361..605269) 1 NC_009616.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 605269 5296567 Tmel_0570 Thermosipho melanesiensis BI429 spermidine synthase YP_001305822.1 604361 R 391009 CDS YP_001305823.1 150020469 5296568 complement(605272..605664) 1 NC_009616.1 PFAM: S-adenosylmethionine decarboxylase related; adenosylmethionine decarboxylase 605664 5296568 Tmel_0571 Thermosipho melanesiensis BI429 adenosylmethionine decarboxylase YP_001305823.1 605272 R 391009 CDS YP_001305824.1 150020470 5296908 complement(605685..606221) 1 NC_009616.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; cupin 2 domain-containing protein 606221 5296908 Tmel_0572 Thermosipho melanesiensis BI429 cupin 2 domain-containing protein YP_001305824.1 605685 R 391009 CDS YP_001305825.1 150020471 5296909 606415..607839 1 NC_009616.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphomannomutase 607839 5296909 Tmel_0573 Thermosipho melanesiensis BI429 phosphomannomutase YP_001305825.1 606415 D 391009 CDS YP_001305826.1 150020472 5296669 complement(607856..608638) 1 NC_009616.1 hypothetical protein 608638 5296669 Tmel_0574 Thermosipho melanesiensis BI429 hypothetical protein YP_001305826.1 607856 R 391009 CDS YP_001305827.1 150020473 5296918 complement(608656..609321) 1 NC_009616.1 PFAM: protein of unknown function DUF554; hypothetical protein 609321 5296918 Tmel_0575 Thermosipho melanesiensis BI429 hypothetical protein YP_001305827.1 608656 R 391009 CDS YP_001305828.1 150020474 5296919 complement(609337..610170) 1 NC_009616.1 PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 610170 5296919 Tmel_0576 Thermosipho melanesiensis BI429 hypothetical protein YP_001305828.1 609337 R 391009 CDS YP_001305829.1 150020475 5297042 complement(610151..610567) 1 NC_009616.1 PFAM: protein of unknown function UPF0054; hypothetical protein 610567 5297042 Tmel_0577 Thermosipho melanesiensis BI429 hypothetical protein YP_001305829.1 610151 R 391009 CDS YP_001305830.1 150020476 5297043 complement(610551..611912) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 611912 5297043 Tmel_0578 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001305830.1 610551 R 391009 CDS YP_001305831.1 150020477 5296657 complement(611899..612855) 1 NC_009616.1 PFAM: PhoH family protein; PhoH family protein 612855 5296657 Tmel_0579 Thermosipho melanesiensis BI429 PhoH family protein YP_001305831.1 611899 R 391009 CDS YP_001305832.1 150020478 5297453 complement(612865..613560) 1 NC_009616.1 SMART: Tetratricopeptide domain protein; tetratricopeptide domain-containing protein 613560 5297453 Tmel_0580 Thermosipho melanesiensis BI429 tetratricopeptide domain-containing protein YP_001305832.1 612865 R 391009 CDS YP_001305833.1 150020479 5297454 complement(613588..614466) 1 NC_009616.1 TIGRFAM: LAO/AO transport system ATPase; PFAM: cobalamin synthesis protein, P47K; ArgK protein; LAO/AO transport system ATPase 614466 5297454 Tmel_0581 Thermosipho melanesiensis BI429 LAO/AO transport system ATPase YP_001305833.1 613588 R 391009 CDS YP_001305834.1 150020480 5296557 complement(614463..614864) 1 NC_009616.1 PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 614864 5296557 Tmel_0582 Thermosipho melanesiensis BI429 cobalamin B12-binding domain-containing protein YP_001305834.1 614463 R 391009 CDS YP_001305835.1 150020481 5296558 complement(614875..615270) 1 NC_009616.1 PFAM: biotin/lipoyl attachment domain-containing protein; biotin/lipoyl attachment domain-containing protein 615270 5296558 Tmel_0583 Thermosipho melanesiensis BI429 biotin/lipoyl attachment domain-containing protein YP_001305835.1 614875 R 391009 CDS YP_001305836.1 150020482 5296823 complement(615243..615554) 1 NC_009616.1 hypothetical protein 615554 5296823 Tmel_0584 Thermosipho melanesiensis BI429 hypothetical protein YP_001305836.1 615243 R 391009 CDS YP_001305837.1 150020483 5297237 complement(615565..617103) 1 NC_009616.1 PFAM: carboxyl transferase; carboxyl transferase 617103 5297237 Tmel_0585 Thermosipho melanesiensis BI429 carboxyl transferase YP_001305837.1 615565 R 391009 CDS YP_001305838.1 150020484 5297238 complement(617118..617525) 1 NC_009616.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 617525 5297238 Tmel_0586 Thermosipho melanesiensis BI429 glyoxalase/bleomycin resistance protein/dioxygenase YP_001305838.1 617118 R 391009 CDS YP_001305839.1 150020485 5297195 complement(617590..617907) 1 NC_009616.1 PFAM: cyclic nucleotide-binding; cyclic nucleotide-binding protein 617907 5297195 Tmel_0587 Thermosipho melanesiensis BI429 cyclic nucleotide-binding protein YP_001305839.1 617590 R 391009 CDS YP_001305840.1 150020486 5297196 complement(617894..618613) 1 NC_009616.1 hypothetical protein 618613 5297196 Tmel_0588 Thermosipho melanesiensis BI429 hypothetical protein YP_001305840.1 617894 R 391009 CDS YP_001305841.1 150020487 5296895 complement(618619..621180) 1 NC_009616.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 621180 secA 5296895 secA Thermosipho melanesiensis BI429 preprotein translocase subunit SecA YP_001305841.1 618619 R 391009 CDS YP_001305842.1 150020488 5296965 complement(621196..622245) 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase 622245 5296965 Tmel_0590 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001305842.1 621196 R 391009 CDS YP_001305843.1 150020489 5296966 622347..622820 1 NC_009616.1 PFAM: Rubrerythrin; rubrerythrin 622820 5296966 Tmel_0591 Thermosipho melanesiensis BI429 rubrerythrin YP_001305843.1 622347 D 391009 CDS YP_001305844.1 150020490 5297445 complement(622817..623581) 1 NC_009616.1 hypothetical protein 623581 5297445 Tmel_0592 Thermosipho melanesiensis BI429 hypothetical protein YP_001305844.1 622817 R 391009 CDS YP_001305845.1 150020491 5297446 complement(623568..623954) 1 NC_009616.1 hypothetical protein 623954 5297446 Tmel_0593 Thermosipho melanesiensis BI429 hypothetical protein YP_001305845.1 623568 R 391009 CDS YP_001305846.1 150020492 5297003 complement(624015..626396) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 626396 5297003 Tmel_0594 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305846.1 624015 R 391009 CDS YP_001305847.1 150020493 5296779 complement(626396..628102) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 628102 5296779 Tmel_0595 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305847.1 626396 R 391009 CDS YP_001305848.1 150020494 5296780 complement(628161..629333) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 629333 5296780 Tmel_0596 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305848.1 628161 R 391009 CDS YP_001305849.1 150020495 5296938 complement(629425..631626) 1 NC_009616.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase 631626 5296938 Tmel_0597 Thermosipho melanesiensis BI429 ATPase YP_001305849.1 629425 R 391009 CDS YP_001305850.1 150020496 5296939 complement(631628..632719) 1 NC_009616.1 TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; Amidohydrolase 3; isoaspartyl dipeptidase 632719 5296939 Tmel_0598 Thermosipho melanesiensis BI429 isoaspartyl dipeptidase YP_001305850.1 631628 R 391009 CDS YP_001305851.1 150020497 5296481 632924..633415 1 NC_009616.1 PFAM: Abortive infection protein; abortive infection protein 633415 5296481 Tmel_0599 Thermosipho melanesiensis BI429 abortive infection protein YP_001305851.1 632924 D 391009 CDS YP_001305852.1 150020498 5297451 633457..633813 1 NC_009616.1 PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein 633813 5297451 Tmel_0600 Thermosipho melanesiensis BI429 dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_001305852.1 633457 D 391009 CDS YP_001305853.1 150020499 5297452 complement(633834..634784) 1 NC_009616.1 PFAM: SufBD protein; SufBD protein 634784 5297452 Tmel_0601 Thermosipho melanesiensis BI429 SufBD protein YP_001305853.1 633834 R 391009 CDS YP_001305854.1 150020500 5297053 complement(634774..635517) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 635517 5297053 Tmel_0602 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305854.1 634774 R 391009 CDS YP_001305855.1 150020501 5297054 complement(635648..636886) 1 NC_009616.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Glu/Leu/Phe/Val dehydrogenase, C terminal 636886 5297054 Tmel_0603 Thermosipho melanesiensis BI429 Glu/Leu/Phe/Val dehydrogenase, C terminal YP_001305855.1 635648 R 391009 CDS YP_001305856.1 150020502 5298334 647362..649314 1 NC_009616.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 649314 5298334 Tmel_0604 Thermosipho melanesiensis BI429 anaerobic ribonucleoside triphosphate reductase YP_001305856.1 647362 D 391009 CDS YP_001305857.1 150020503 5297258 649325..649855 1 NC_009616.1 hypothetical protein 649855 5297258 Tmel_0605 Thermosipho melanesiensis BI429 hypothetical protein YP_001305857.1 649325 D 391009 CDS YP_001305858.1 150020504 5297259 649837..652338 1 NC_009616.1 TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 652338 5297259 Tmel_0606 Thermosipho melanesiensis BI429 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_001305858.1 649837 D 391009 CDS YP_001305859.1 150020505 5298351 653346..653819 1 NC_009616.1 hypothetical protein 653819 5298351 Tmel_0610 Thermosipho melanesiensis BI429 hypothetical protein YP_001305859.1 653346 D 391009 CDS YP_001305860.1 150020506 5296907 complement(653854..654606) 1 NC_009616.1 hypothetical protein 654606 5296907 Tmel_0611 Thermosipho melanesiensis BI429 hypothetical protein YP_001305860.1 653854 R 391009 CDS YP_001305861.1 150020507 5298022 complement(655077..655607) 1 NC_009616.1 hypothetical protein 655607 5298022 Tmel_0612 Thermosipho melanesiensis BI429 hypothetical protein YP_001305861.1 655077 R 391009 CDS YP_001305862.1 150020508 5296720 complement(655592..655810) 1 NC_009616.1 hypothetical protein 655810 5296720 Tmel_0613 Thermosipho melanesiensis BI429 hypothetical protein YP_001305862.1 655592 R 391009 CDS YP_001305863.1 150020509 5296721 complement(655855..657438) 1 NC_009616.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; OB-fold, tRNA/helicase-type nucleic acid binding protein 657438 5296721 Tmel_0614 Thermosipho melanesiensis BI429 OB-fold, tRNA/helicase-type nucleic acid binding protein YP_001305863.1 655855 R 391009 CDS YP_001305864.1 150020510 5296708 complement(657498..657929) 1 NC_009616.1 hypothetical protein 657929 5296708 Tmel_0615 Thermosipho melanesiensis BI429 hypothetical protein YP_001305864.1 657498 R 391009 CDS YP_001305865.1 150020511 5296709 complement(658247..658807) 1 NC_009616.1 PFAM: glycerol-3-phosphate responsive antiterminator; glycerol-3-phosphate responsive antiterminator 658807 5296709 Tmel_0616 Thermosipho melanesiensis BI429 glycerol-3-phosphate responsive antiterminator YP_001305865.1 658247 R 391009 CDS YP_001305866.1 150020512 5297791 complement(658800..660269) 1 NC_009616.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; glycerol kinase 660269 5297791 Tmel_0617 Thermosipho melanesiensis BI429 glycerol kinase YP_001305866.1 658800 R 391009 CDS YP_001305867.1 150020513 5296954 complement(660288..660650) 1 NC_009616.1 PFAM: protein of unknown function DUF1667; hypothetical protein 660650 5296954 Tmel_0618 Thermosipho melanesiensis BI429 hypothetical protein YP_001305867.1 660288 R 391009 CDS YP_001305868.1 150020514 5296955 complement(660643..661863) 1 NC_009616.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 661863 5296955 Tmel_0619 Thermosipho melanesiensis BI429 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001305868.1 660643 R 391009 CDS YP_001305869.1 150020515 5296995 complement(661860..663296) 1 NC_009616.1 PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; FAD dependent oxidoreductase 663296 5296995 Tmel_0620 Thermosipho melanesiensis BI429 FAD dependent oxidoreductase YP_001305869.1 661860 R 391009 CDS YP_001305870.1 150020516 5296996 complement(663417..664736) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 664736 5296996 Tmel_0621 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001305870.1 663417 R 391009 CDS YP_001305871.1 150020517 5296739 664975..665775 1 NC_009616.1 PFAM: flagellin domain protein; flagellin domain-containing protein 665775 5296739 Tmel_0622 Thermosipho melanesiensis BI429 flagellin domain-containing protein YP_001305871.1 664975 D 391009 CDS YP_001305872.1 150020518 5298143 complement(665942..666445) 1 NC_009616.1 PFAM: NUDIX hydrolase; NUDIX hydrolase 666445 5298143 Tmel_0623 Thermosipho melanesiensis BI429 NUDIX hydrolase YP_001305872.1 665942 R 391009 CDS YP_001305873.1 150020519 5297313 complement(666447..667073) 1 NC_009616.1 PFAM: Haloacid dehalogenase domain protein hydrolase; hydrolase 667073 5297313 Tmel_0624 Thermosipho melanesiensis BI429 hydrolase YP_001305873.1 666447 R 391009 CDS YP_001305874.1 150020520 5296984 667118..667477 1 NC_009616.1 PFAM: protein of unknown function DUF123; hypothetical protein 667477 5296984 Tmel_0625 Thermosipho melanesiensis BI429 hypothetical protein YP_001305874.1 667118 D 391009 CDS YP_001305875.1 150020521 5296985 667575..668801 1 NC_009616.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 668801 clpX 5296985 clpX Thermosipho melanesiensis BI429 ATP-dependent protease ATP-binding subunit ClpX YP_001305875.1 667575 D 391009 CDS YP_001305876.1 150020522 5296750 668802..669779 1 NC_009616.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 669779 5296750 Tmel_0627 Thermosipho melanesiensis BI429 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001305876.1 668802 D 391009 CDS YP_001305877.1 150020523 5297587 complement(669769..670692) 1 NC_009616.1 PFAM: CBS domain containing protein; ATP-binding region, ATPase domain protein domain protein; signal transduction protein 670692 5297587 Tmel_0628 Thermosipho melanesiensis BI429 signal transduction protein YP_001305877.1 669769 R 391009 CDS YP_001305878.1 150020524 5297588 complement(670738..671589) 1 NC_009616.1 TIGRFAM: HflC protein; PFAM: band 7 protein; HflC protein 671589 5297588 Tmel_0629 Thermosipho melanesiensis BI429 HflC protein YP_001305878.1 670738 R 391009 CDS YP_001305879.1 150020525 5297013 complement(671586..672515) 1 NC_009616.1 TIGRFAM: HflK protein; PFAM: band 7 protein; HflK protein 672515 5297013 Tmel_0630 Thermosipho melanesiensis BI429 HflK protein YP_001305879.1 671586 R 391009 CDS YP_001305880.1 150020526 5297014 complement(672555..673064) 1 NC_009616.1 PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; rubrerythrin 673064 5297014 Tmel_0631 Thermosipho melanesiensis BI429 rubrerythrin YP_001305880.1 672555 R 391009 CDS YP_001305881.1 150020527 5297369 complement(673090..675075) 1 NC_009616.1 glycine--tRNA ligase 675075 5297369 Tmel_0632 Thermosipho melanesiensis BI429 glycine--tRNA ligase YP_001305881.1 673090 R 391009 CDS YP_001305882.1 150020528 5297275 complement(675075..675926) 1 NC_009616.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 675926 glyQ 5297275 glyQ Thermosipho melanesiensis BI429 glycyl-tRNA synthetase subunit alpha YP_001305882.1 675075 R 391009 CDS YP_001305883.1 150020529 5297276 complement(675940..676575) 1 NC_009616.1 hypothetical protein 676575 5297276 Tmel_0634 Thermosipho melanesiensis BI429 hypothetical protein YP_001305883.1 675940 R 391009 CDS YP_001305884.1 150020530 5297153 complement(676575..677639) 1 NC_009616.1 PFAM: cell cycle protein; cell cycle protein 677639 5297153 Tmel_0635 Thermosipho melanesiensis BI429 cell cycle protein YP_001305884.1 676575 R 391009 CDS YP_001305885.1 150020531 5298183 677988..678347 1 NC_009616.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 678347 rpsF 5298183 rpsF Thermosipho melanesiensis BI429 30S ribosomal protein S6 YP_001305885.1 677988 D 391009 CDS YP_001305886.1 150020532 5297490 678344..678745 1 NC_009616.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; single-strand binding protein 678745 5297490 Tmel_0637 Thermosipho melanesiensis BI429 single-strand binding protein YP_001305886.1 678344 D 391009 CDS YP_001305887.1 150020533 5297761 678768..678995 1 NC_009616.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 678995 rpsR 5297761 rpsR Thermosipho melanesiensis BI429 30S ribosomal protein S18 YP_001305887.1 678768 D 391009 CDS YP_001305888.1 150020534 5298414 679233..679382 1 NC_009616.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 679382 rpmG 5298414 rpmG Thermosipho melanesiensis BI429 50S ribosomal protein L33 YP_001305888.1 679233 D 391009 CDS YP_001305889.1 150020535 5298083 679490..679678 1 NC_009616.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; preprotein translocase subunit SecE 679678 5298083 Tmel_0640 Thermosipho melanesiensis BI429 preprotein translocase subunit SecE YP_001305889.1 679490 D 391009 CDS YP_001305890.1 150020536 5297352 679697..680767 1 NC_009616.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein; NusG antitermination factor 680767 5297352 Tmel_0641 Thermosipho melanesiensis BI429 NusG antitermination factor YP_001305890.1 679697 D 391009 CDS YP_001305891.1 150020537 5297283 680814..681239 1 NC_009616.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 681239 rplK 5297283 rplK Thermosipho melanesiensis BI429 50S ribosomal protein L11 YP_001305891.1 680814 D 391009 CDS YP_001305892.1 150020538 5296661 681266..681964 1 NC_009616.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 681964 rplA 5296661 rplA Thermosipho melanesiensis BI429 50S ribosomal protein L1 YP_001305892.1 681266 D 391009 CDS YP_001305893.1 150020539 5296662 complement(682001..682750) 1 NC_009616.1 PFAM: protein of unknown function DUF368; hypothetical protein 682750 5296662 Tmel_0644 Thermosipho melanesiensis BI429 hypothetical protein YP_001305893.1 682001 R 391009 CDS YP_001305894.1 150020540 5298373 complement(683202..684194) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 684194 5298373 Tmel_0645 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001305894.1 683202 R 391009 CDS YP_001305895.1 150020541 5297354 684379..684867 1 NC_009616.1 PFAM: dihydrofolate reductase region; dihydrofolate reductase region 684867 5297354 Tmel_0646 Thermosipho melanesiensis BI429 dihydrofolate reductase region YP_001305895.1 684379 D 391009 CDS YP_001305896.1 150020542 5297690 complement(684859..685308) 1 NC_009616.1 hypothetical protein 685308 5297690 Tmel_0647 Thermosipho melanesiensis BI429 hypothetical protein YP_001305896.1 684859 R 391009 CDS YP_001305897.1 150020543 5297952 complement(685321..686418) 1 NC_009616.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD-binding subunit 686418 5297952 Tmel_0648 Thermosipho melanesiensis BI429 oxidoreductase FAD-binding subunit YP_001305897.1 685321 R 391009 CDS YP_001305898.1 150020544 5297953 complement(686428..687018) 1 NC_009616.1 PFAM: RnfA-Nqr electron transport subunit; RnfA-Nqr electron transport subunit 687018 5297953 Tmel_0649 Thermosipho melanesiensis BI429 RnfA-Nqr electron transport subunit YP_001305898.1 686428 R 391009 CDS YP_001305899.1 150020545 5297491 complement(687011..687607) 1 NC_009616.1 PFAM: RnfA-Nqr electron transport subunit; RnfA-Nqr electron transport subunit 687607 5297491 Tmel_0650 Thermosipho melanesiensis BI429 RnfA-Nqr electron transport subunit YP_001305899.1 687011 R 391009 CDS YP_001305900.1 150020546 5297492 complement(687600..688211) 1 NC_009616.1 PFAM: FMN-binding domain protein; FMN-binding domain-containing protein 688211 5297492 Tmel_0651 Thermosipho melanesiensis BI429 FMN-binding domain-containing protein YP_001305900.1 687600 R 391009 CDS YP_001305901.1 150020547 5296551 complement(688208..689095) 1 NC_009616.1 PFAM: NQR2 and RnfD family protein; NQR2 and RnfD family protein 689095 5296551 Tmel_0652 Thermosipho melanesiensis BI429 NQR2 and RnfD family protein YP_001305901.1 688208 R 391009 CDS YP_001305902.1 150020548 5297800 complement(689202..690239) 1 NC_009616.1 PFAM: Nucleotidyl transferase; mannose-1-phosphate guanylyltransferase (GDP) 690239 5297800 Tmel_0653 Thermosipho melanesiensis BI429 mannose-1-phosphate guanylyltransferase (GDP) YP_001305902.1 689202 R 391009 CDS YP_001305903.1 150020549 5297801 complement(690258..691211) 1 NC_009616.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; Electron transfer flavoprotein, alpha subunit-like; electron transfer flavoprotein subunit alpha-like protein 691211 5297801 Tmel_0654 Thermosipho melanesiensis BI429 electron transfer flavoprotein subunit alpha-like protein YP_001305903.1 690258 R 391009 CDS YP_001305904.1 150020550 5296627 complement(691219..691998) 1 NC_009616.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; electron transfer flavoprotein, alpha/beta-subunit-like protein 691998 5296627 Tmel_0655 Thermosipho melanesiensis BI429 electron transfer flavoprotein, alpha/beta-subunit-like protein YP_001305904.1 691219 R 391009 CDS YP_001305905.1 150020551 5296628 complement(692003..693145) 1 NC_009616.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; acyl-CoA dehydrogenase domain-containing protein 693145 5296628 Tmel_0656 Thermosipho melanesiensis BI429 acyl-CoA dehydrogenase domain-containing protein YP_001305905.1 692003 R 391009 CDS YP_001305906.1 150020552 5297096 693408..694937 1 NC_009616.1 PFAM: protein of unknown function DUF342; hypothetical protein 694937 5297096 Tmel_0657 Thermosipho melanesiensis BI429 hypothetical protein YP_001305906.1 693408 D 391009 CDS YP_001305907.1 150020553 5297381 694934..696595 1 NC_009616.1 hypothetical protein 696595 5297381 Tmel_0658 Thermosipho melanesiensis BI429 hypothetical protein YP_001305907.1 694934 D 391009 CDS YP_001305908.1 150020554 5297382 complement(696625..698640) 1 NC_009616.1 PFAM: lipopolysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 698640 5297382 Tmel_0659 Thermosipho melanesiensis BI429 lipopolysaccharide biosynthesis protein YP_001305908.1 696625 R 391009 CDS YP_001305909.1 150020555 5297235 complement(698656..701127) 1 NC_009616.1 PFAM: polysaccharide export protein; polysaccharide export protein 701127 5297235 Tmel_0660 Thermosipho melanesiensis BI429 polysaccharide export protein YP_001305909.1 698656 R 391009 CDS YP_001305910.1 150020556 5297236 701201..702076 1 NC_009616.1 PFAM: phosphoesterase, RecJ domain protein; phosphoesterase domain-containing protein 702076 5297236 Tmel_0661 Thermosipho melanesiensis BI429 phosphoesterase domain-containing protein YP_001305910.1 701201 D 391009 CDS YP_001305911.1 150020557 5297359 702081..702884 1 NC_009616.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; phosphotransferase domain-containing protein 702884 5297359 Tmel_0662 Thermosipho melanesiensis BI429 phosphotransferase domain-containing protein YP_001305911.1 702081 D 391009 CDS YP_001305912.1 150020558 5296956 702958..704433 1 NC_009616.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramyl-tripeptide synthetase 704433 5296956 Tmel_0663 Thermosipho melanesiensis BI429 UDP-N-acetylmuramyl-tripeptide synthetase YP_001305912.1 702958 D 391009 CDS YP_001305913.1 150020559 5296957 704430..704777 1 NC_009616.1 hypothetical protein 704777 5296957 Tmel_0664 Thermosipho melanesiensis BI429 hypothetical protein YP_001305913.1 704430 D 391009 CDS YP_001305914.1 150020560 5297211 704840..705646 1 NC_009616.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 705646 mraY 5297211 mraY Thermosipho melanesiensis BI429 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001305914.1 704840 D 391009 CDS YP_001305915.1 150020561 5297212 705651..706487 1 NC_009616.1 PFAM: glycosyl transferase, family 4; glycosyl transferase family protein 706487 5297212 Tmel_0666 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001305915.1 705651 D 391009 CDS YP_001305916.1 150020562 5297291 complement(706489..706755) 1 NC_009616.1 hypothetical protein 706755 5297291 Tmel_0667 Thermosipho melanesiensis BI429 hypothetical protein YP_001305916.1 706489 R 391009 CDS YP_001305917.1 150020563 5297071 complement(706766..707755) 1 NC_009616.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 707755 flgI 5297071 flgI Thermosipho melanesiensis BI429 flagellar basal body P-ring protein YP_001305917.1 706766 R 391009 CDS YP_001305918.1 150020564 5297072 complement(707766..708350) 1 NC_009616.1 flagellar basal body L-ring protein-like protein 708350 5297072 Tmel_0669 Thermosipho melanesiensis BI429 flagellar basal body L-ring protein-like protein YP_001305918.1 707766 R 391009 CDS YP_001305919.1 150020565 5296798 complement(708347..709279) 1 NC_009616.1 flagellar basal body P-ring biosynthesis protein-like protein 709279 5296798 Tmel_0670 Thermosipho melanesiensis BI429 flagellar basal body P-ring biosynthesis protein-like protein YP_001305919.1 708347 R 391009 CDS YP_001305920.1 150020566 5296799 complement(709281..711164) 1 NC_009616.1 TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II; DNA gyrase subunit B 711164 5296799 Tmel_0671 Thermosipho melanesiensis BI429 DNA gyrase subunit B YP_001305920.1 709281 R 391009 CDS YP_001305921.1 150020567 5296660 complement(711154..711456) 1 NC_009616.1 hypothetical protein 711456 5296660 Tmel_0672 Thermosipho melanesiensis BI429 hypothetical protein YP_001305921.1 711154 R 391009 CDS YP_001305922.1 150020568 5296794 complement(711431..712174) 1 NC_009616.1 PFAM: aminotransferase, class IV; class IV aminotransferase 712174 5296794 Tmel_0673 Thermosipho melanesiensis BI429 class IV aminotransferase YP_001305922.1 711431 R 391009 CDS YP_001305923.1 150020569 5296795 complement(712149..713438) 1 NC_009616.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein 713438 5296795 Tmel_0674 Thermosipho melanesiensis BI429 MiaB-like tRNA modifying protein YP_001305923.1 712149 R 391009 CDS YP_001305924.1 150020570 5297284 complement(713440..713883) 1 NC_009616.1 PFAM: CBS domain containing protein; signal transduction protein 713883 5297284 Tmel_0675 Thermosipho melanesiensis BI429 signal transduction protein YP_001305924.1 713440 R 391009 CDS YP_001305925.1 150020571 5297285 complement(713885..714838) 1 NC_009616.1 PFAM: PfkB domain protein; ribokinase-like domain-containing protein 714838 5297285 Tmel_0676 Thermosipho melanesiensis BI429 ribokinase-like domain-containing protein YP_001305925.1 713885 R 391009 CDS YP_001305926.1 150020572 5297084 complement(714844..715563) 1 NC_009616.1 cobalamin/Fe3+-siderophores ABC transporter ATPase-like protein 715563 5297084 Tmel_0677 Thermosipho melanesiensis BI429 cobalamin/Fe3+-siderophores ABC transporter ATPase-like protein YP_001305926.1 714844 R 391009 CDS YP_001305927.1 150020573 5297530 complement(715919..716494) 1 NC_009616.1 hypothetical protein 716494 5297530 Tmel_0678 Thermosipho melanesiensis BI429 hypothetical protein YP_001305927.1 715919 R 391009 CDS YP_001305928.1 150020574 5297531 complement(716506..719274) 1 NC_009616.1 hypothetical protein 719274 5297531 Tmel_0679 Thermosipho melanesiensis BI429 hypothetical protein YP_001305928.1 716506 R 391009 CDS YP_001305929.1 150020575 5296607 complement(719290..720822) 1 NC_009616.1 hypothetical protein 720822 5296607 Tmel_0680 Thermosipho melanesiensis BI429 hypothetical protein YP_001305929.1 719290 R 391009 CDS YP_001305930.1 150020576 5296608 complement(720892..722004) 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 722004 5296608 Tmel_0681 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001305930.1 720892 R 391009 CDS YP_001305931.1 150020577 5296734 722087..724312 1 NC_009616.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; heavy metal translocating P-type ATPase 724312 5296734 Tmel_0682 Thermosipho melanesiensis BI429 heavy metal translocating P-type ATPase YP_001305931.1 722087 D 391009 CDS YP_001305932.1 150020578 5297728 724324..724545 1 NC_009616.1 hypothetical protein 724545 5297728 Tmel_0683 Thermosipho melanesiensis BI429 hypothetical protein YP_001305932.1 724324 D 391009 CDS YP_001305933.1 150020579 5297729 724550..724744 1 NC_009616.1 hypothetical protein 724744 5297729 Tmel_0684 Thermosipho melanesiensis BI429 hypothetical protein YP_001305933.1 724550 D 391009 CDS YP_001305934.1 150020580 5296633 724757..724963 1 NC_009616.1 PFAM: Heavy metal transport/detoxification protein; heavy metal transport/detoxification protein 724963 5296633 Tmel_0685 Thermosipho melanesiensis BI429 heavy metal transport/detoxification protein YP_001305934.1 724757 D 391009 CDS YP_001305935.1 150020581 5296634 complement(724989..726263) 1 NC_009616.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 726263 glyA 5296634 glyA Thermosipho melanesiensis BI429 serine hydroxymethyltransferase YP_001305935.1 724989 R 391009 CDS YP_001305936.1 150020582 5297207 726630..727046 1 NC_009616.1 hypothetical protein 727046 5297207 Tmel_0687 Thermosipho melanesiensis BI429 hypothetical protein YP_001305936.1 726630 D 391009 CDS YP_001305937.1 150020583 5296569 727197..728225 1 NC_009616.1 PFAM: ROK family protein; ROK family protein 728225 5296569 Tmel_0688 Thermosipho melanesiensis BI429 ROK family protein YP_001305937.1 727197 D 391009 CDS YP_001305938.1 150020584 5296570 728218..729549 1 NC_009616.1 PFAM: glycoside hydrolase, family 3 domain protein; glycoside hydrolase family 3 protein 729549 5296570 Tmel_0689 Thermosipho melanesiensis BI429 glycoside hydrolase family 3 protein YP_001305938.1 728218 D 391009 CDS YP_001305939.1 150020585 5297232 729546..730754 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 730754 5297232 Tmel_0690 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001305939.1 729546 D 391009 CDS YP_001305940.1 150020586 5297233 730791..731678 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 731678 5297233 Tmel_0691 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305940.1 730791 D 391009 CDS YP_001305941.1 150020587 5297161 731675..732847 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 732847 5297161 Tmel_0692 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305941.1 731675 D 391009 CDS YP_001305942.1 150020588 5297308 732844..733752 1 NC_009616.1 PFAM: sugar isomerase (SIS); sugar isomerase (SIS) 733752 5297308 Tmel_0693 Thermosipho melanesiensis BI429 sugar isomerase (SIS) YP_001305942.1 732844 D 391009 CDS YP_001305943.1 150020589 5297309 733763..734812 1 NC_009616.1 PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 734812 5297309 Tmel_0694 Thermosipho melanesiensis BI429 N-acetylglucosamine-6-phosphate deacetylase YP_001305943.1 733763 D 391009 CDS YP_001305944.1 150020590 5297331 735101..736129 1 NC_009616.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 736129 5297331 Tmel_0695 Thermosipho melanesiensis BI429 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001305944.1 735101 D 391009 CDS YP_001305945.1 150020591 5297332 736126..736464 1 NC_009616.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; cobalamin (vitamin B12) biosynthesis CbiX protein 736464 5297332 Tmel_0696 Thermosipho melanesiensis BI429 cobalamin (vitamin B12) biosynthesis CbiX protein YP_001305945.1 736126 D 391009 CDS YP_001305946.1 150020592 5297147 736461..737078 1 NC_009616.1 PFAM: Precorrin-8X methylmutase CbiC/CobH; precorrin-8X methylmutase CbiC/CobH 737078 5297147 Tmel_0697 Thermosipho melanesiensis BI429 precorrin-8X methylmutase CbiC/CobH YP_001305946.1 736461 D 391009 CDS YP_001305947.1 150020593 5296541 737071..738129 1 NC_009616.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 738129 cbiD 5296541 cbiD Thermosipho melanesiensis BI429 cobalt-precorrin-6A synthase YP_001305947.1 737071 D 391009 CDS YP_001305948.1 150020594 5296542 738098..738685 1 NC_009616.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6Y C5,15-methyltransferase subunit CbiE 738685 5296542 Tmel_0699 Thermosipho melanesiensis BI429 precorrin-6Y C5,15-methyltransferase subunit CbiE YP_001305948.1 738098 D 391009 CDS YP_001305949.1 150020595 5296516 738690..739229 1 NC_009616.1 TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6Y C5,15-methyltransferase subunit CbiT 739229 5296516 Tmel_0700 Thermosipho melanesiensis BI429 precorrin-6Y C5,15-methyltransferase subunit CbiT YP_001305949.1 738690 D 391009 CDS YP_001305950.1 150020596 5296517 739226..739861 1 NC_009616.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 739861 5296517 Tmel_0701 Thermosipho melanesiensis BI429 uroporphyrin-III C/tetrapyrrole methyltransferase YP_001305950.1 739226 D 391009 CDS YP_001305951.1 150020597 5296813 739862..740596 1 NC_009616.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-4 C11-methyltransferase 740596 5296813 Tmel_0702 Thermosipho melanesiensis BI429 precorrin-4 C11-methyltransferase YP_001305951.1 739862 D 391009 CDS YP_001305952.1 150020598 5297632 740593..741555 1 NC_009616.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; cobalamin biosynthesis protein CbiG 741555 5297632 Tmel_0703 Thermosipho melanesiensis BI429 cobalamin biosynthesis protein CbiG YP_001305952.1 740593 D 391009 CDS YP_001305953.1 150020599 5297633 741557..742264 1 NC_009616.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 742264 5297633 Tmel_0704 Thermosipho melanesiensis BI429 uroporphyrin-III C/tetrapyrrole methyltransferase YP_001305953.1 741557 D 391009 CDS YP_001305954.1 150020600 5297065 742261..743001 1 NC_009616.1 TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 743001 5297065 Tmel_0705 Thermosipho melanesiensis BI429 precorrin-6x reductase YP_001305954.1 742261 D 391009 CDS YP_001305955.1 150020601 5297066 742973..744079 1 NC_009616.1 PFAM: glutamyl-tRNA reductase; Shikimate/quinate 5-dehydrogenase; glutamyl-tRNA reductase 744079 5297066 Tmel_0706 Thermosipho melanesiensis BI429 glutamyl-tRNA reductase YP_001305955.1 742973 D 391009 CDS YP_001305956.1 150020602 5297105 744076..744915 1 NC_009616.1 TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; porphobilinogen deaminase 744915 5297105 Tmel_0707 Thermosipho melanesiensis BI429 porphobilinogen deaminase YP_001305956.1 744076 D 391009 CDS YP_001305957.1 150020603 5296896 744906..746300 1 NC_009616.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; uroporphyrin-III C-methyltransferase 746300 5296896 Tmel_0708 Thermosipho melanesiensis BI429 uroporphyrin-III C-methyltransferase YP_001305957.1 744906 D 391009 CDS YP_001305958.1 150020604 5296897 746272..747219 1 NC_009616.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 747219 5296897 Tmel_0709 Thermosipho melanesiensis BI429 delta-aminolevulinic acid dehydratase YP_001305958.1 746272 D 391009 CDS YP_001305959.1 150020605 5297750 747201..747647 1 NC_009616.1 siroheme synthase 747647 5297750 Tmel_0710 Thermosipho melanesiensis BI429 siroheme synthase YP_001305959.1 747201 D 391009 CDS YP_001305960.1 150020606 5297751 747640..748911 1 NC_009616.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 748911 5297751 Tmel_0711 Thermosipho melanesiensis BI429 glutamate-1-semialdehyde aminotransferase YP_001305960.1 747640 D 391009 CDS YP_001305961.1 150020607 5296964 748908..749615 1 NC_009616.1 TIGRFAM: cobalamin biosynthesis protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; cobalamin biosynthesis protein CbiM 749615 5296964 Tmel_0712 Thermosipho melanesiensis BI429 cobalamin biosynthesis protein CbiM YP_001305961.1 748908 D 391009 CDS YP_001305962.1 150020608 5297473 749615..749896 1 NC_009616.1 TIGRFAM: cobalt transport protein; PFAM: Cobalt transport protein CbiN; cobalt transport protein 749896 5297473 Tmel_0713 Thermosipho melanesiensis BI429 cobalt transport protein YP_001305962.1 749615 D 391009 CDS YP_001305963.1 150020609 5297474 749886..750566 1 NC_009616.1 PFAM: cobalt transport protein; cobalt transport protein 750566 5297474 Tmel_0714 Thermosipho melanesiensis BI429 cobalt transport protein YP_001305963.1 749886 D 391009 CDS YP_001305964.1 150020610 5297936 750563..751276 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 751276 5297936 Tmel_0715 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305964.1 750563 D 391009 CDS YP_001305965.1 150020611 5297937 751273..751905 1 NC_009616.1 TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region; putative ATP binding protein 751905 5297937 Tmel_0716 Thermosipho melanesiensis BI429 putative ATP binding protein YP_001305965.1 751273 D 391009 CDS YP_001305966.1 150020612 5297150 complement(751923..752585) 1 NC_009616.1 PFAM: ribonuclease H; ribonuclease H 752585 5297150 Tmel_0717 Thermosipho melanesiensis BI429 ribonuclease H YP_001305966.1 751923 R 391009 CDS YP_001305967.1 150020613 5296922 complement(752614..754155) 1 NC_009616.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 754155 guaA 5296922 guaA Thermosipho melanesiensis BI429 GMP synthase YP_001305967.1 752614 R 391009 CDS YP_001305968.1 150020614 5296923 complement(754288..754437) 1 NC_009616.1 hypothetical protein 754437 5296923 Tmel_0719 Thermosipho melanesiensis BI429 hypothetical protein YP_001305968.1 754288 R 391009 CDS YP_001305969.1 150020615 5297880 complement(758672..759223) 1 NC_009616.1 PFAM: LemA family protein; LemA family protein 759223 5297880 Tmel_0720 Thermosipho melanesiensis BI429 LemA family protein YP_001305969.1 758672 R 391009 CDS YP_001305970.1 150020616 5297881 complement(759247..760968) 1 NC_009616.1 hypothetical protein 760968 5297881 Tmel_0721 Thermosipho melanesiensis BI429 hypothetical protein YP_001305970.1 759247 R 391009 CDS YP_001305971.1 150020617 5297859 complement(760981..761133) 1 NC_009616.1 hypothetical protein 761133 5297859 Tmel_0722 Thermosipho melanesiensis BI429 hypothetical protein YP_001305971.1 760981 R 391009 CDS YP_001305972.1 150020618 5297106 complement(761181..761783) 1 NC_009616.1 PFAM: putative esterase; putative esterase 761783 5297106 Tmel_0723 Thermosipho melanesiensis BI429 putative esterase YP_001305972.1 761181 R 391009 CDS YP_001305973.1 150020619 5297107 complement(761765..762040) 1 NC_009616.1 hypothetical protein 762040 5297107 Tmel_0724 Thermosipho melanesiensis BI429 hypothetical protein YP_001305973.1 761765 R 391009 CDS YP_001305974.1 150020620 5297807 complement(762071..763327) 1 NC_009616.1 catalyzes the formation of L-tryptophan from indole and L-serine; tryptophan synthase subunit beta 763327 5297807 Tmel_0725 Thermosipho melanesiensis BI429 tryptophan synthase subunit beta YP_001305974.1 762071 R 391009 CDS YP_001305975.1 150020621 5297808 complement(763556..764476) 1 NC_009616.1 PFAM: phosphate transporter; phosphate transporter 764476 5297808 Tmel_0726 Thermosipho melanesiensis BI429 phosphate transporter YP_001305975.1 763556 R 391009 CDS YP_001305976.1 150020622 5297864 complement(764600..766135) 1 NC_009616.1 hypothetical protein 766135 5297864 Tmel_0727 Thermosipho melanesiensis BI429 hypothetical protein YP_001305976.1 764600 R 391009 CDS YP_001305977.1 150020623 5296493 complement(766260..766808) 1 NC_009616.1 PFAM: nitroreductase; nitroreductase 766808 5296493 Tmel_0728 Thermosipho melanesiensis BI429 nitroreductase YP_001305977.1 766260 R 391009 CDS YP_001305978.1 150020624 5296494 complement(766813..769158) 1 NC_009616.1 PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; homocysteine S-methyltransferase 769158 5296494 Tmel_0729 Thermosipho melanesiensis BI429 homocysteine S-methyltransferase YP_001305978.1 766813 R 391009 CDS YP_001305979.1 150020625 5297122 complement(769137..769673) 1 NC_009616.1 PFAM: Vitamin B12 dependent methionine synthase, activation region; vitamin B12 dependent methionine synthase, activation region 769673 5297122 Tmel_0730 Thermosipho melanesiensis BI429 vitamin B12 dependent methionine synthase, activation region YP_001305979.1 769137 R 391009 CDS YP_001305980.1 150020626 5297123 complement(769682..770599) 1 NC_009616.1 PFAM: methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H) 770599 5297123 Tmel_0731 Thermosipho melanesiensis BI429 methylenetetrahydrofolate reductase (NAD(P)H) YP_001305980.1 769682 R 391009 CDS YP_001305981.1 150020627 5297631 complement(770601..771314) 1 NC_009616.1 hypothetical protein 771314 5297631 Tmel_0732 Thermosipho melanesiensis BI429 hypothetical protein YP_001305981.1 770601 R 391009 CDS YP_001305982.1 150020628 5298457 complement(771296..772600) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF39; hypothetical protein 772600 5298457 Tmel_0733 Thermosipho melanesiensis BI429 hypothetical protein YP_001305982.1 771296 R 391009 CDS YP_001305983.1 150020629 5298458 complement(772597..773739) 1 NC_009616.1 PFAM: aspartate/glutamate/uridylate kinase; aspartate kinase 773739 5298458 Tmel_0734 Thermosipho melanesiensis BI429 aspartate kinase YP_001305983.1 772597 R 391009 CDS YP_001305984.1 150020630 5298079 775390..777837 1 NC_009616.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 777837 5298079 Tmel_0736 Thermosipho melanesiensis BI429 alpha amylase catalytic subunit YP_001305984.1 775390 D 391009 CDS YP_001305985.1 150020631 5297573 complement(778015..779085) 1 NC_009616.1 hypothetical protein 779085 5297573 Tmel_0737 Thermosipho melanesiensis BI429 hypothetical protein YP_001305985.1 778015 R 391009 CDS YP_001305986.1 150020632 5297249 complement(779334..779804) 1 NC_009616.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 779804 5297249 Tmel_0738 Thermosipho melanesiensis BI429 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_001305986.1 779334 R 391009 CDS YP_001305987.1 150020633 5297526 complement(779814..781301) 1 NC_009616.1 hypothetical protein 781301 5297526 Tmel_0739 Thermosipho melanesiensis BI429 hypothetical protein YP_001305987.1 779814 R 391009 CDS YP_001305988.1 150020634 5297527 complement(781314..782057) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 782057 5297527 Tmel_0740 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001305988.1 781314 R 391009 CDS YP_001305989.1 150020635 5297566 complement(782032..782679) 1 NC_009616.1 hypothetical protein 782679 5297566 Tmel_0741 Thermosipho melanesiensis BI429 hypothetical protein YP_001305989.1 782032 R 391009 CDS YP_001305990.1 150020636 5297567 complement(782676..783209) 1 NC_009616.1 putative transcriptional regulator 783209 5297567 Tmel_0742 Thermosipho melanesiensis BI429 putative transcriptional regulator YP_001305990.1 782676 R 391009 CDS YP_001305991.1 150020637 5297831 complement(783257..783541) 1 NC_009616.1 hypothetical protein 783541 5297831 Tmel_0743 Thermosipho melanesiensis BI429 hypothetical protein YP_001305991.1 783257 R 391009 CDS YP_001305992.1 150020638 5297441 complement(783538..784797) 1 NC_009616.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 784797 hisS 5297441 hisS Thermosipho melanesiensis BI429 histidyl-tRNA synthetase YP_001305992.1 783538 R 391009 CDS YP_001305993.1 150020639 5297442 complement(784782..785480) 1 NC_009616.1 SMART: Tetratricopeptide domain protein; tetratricopeptide domain-containing protein 785480 5297442 Tmel_0745 Thermosipho melanesiensis BI429 tetratricopeptide domain-containing protein YP_001305993.1 784782 R 391009 CDS YP_001305994.1 150020640 5297612 complement(785455..786276) 1 NC_009616.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3; Cof-like hydrolase 786276 5297612 Tmel_0746 Thermosipho melanesiensis BI429 Cof-like hydrolase YP_001305994.1 785455 R 391009 CDS YP_001305995.1 150020641 5297613 complement(786282..787361) 1 NC_009616.1 TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidyltransferase 787361 5297613 Tmel_0747 Thermosipho melanesiensis BI429 glucose-1-phosphate thymidyltransferase YP_001305995.1 786282 R 391009 CDS YP_001305996.1 150020642 5297882 complement(787383..787916) 1 NC_009616.1 hypothetical protein 787916 5297882 Tmel_0748 Thermosipho melanesiensis BI429 hypothetical protein YP_001305996.1 787383 R 391009 CDS YP_001305997.1 150020643 5298218 788205..790178 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 790178 5298218 Tmel_0749 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001305997.1 788205 D 391009 CDS YP_001305998.1 150020644 5298219 790286..792745 1 NC_009616.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 792745 5298219 Tmel_0750 Thermosipho melanesiensis BI429 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_001305998.1 790286 D 391009 CDS YP_001305999.1 150020645 5298149 complement(792856..793689) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 793689 5298149 Tmel_0751 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001305999.1 792856 R 391009 CDS YP_001306000.1 150020646 5298150 complement(793699..794565) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 794565 5298150 Tmel_0752 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306000.1 793699 R 391009 CDS YP_001306001.1 150020647 5298148 complement(794607..795920) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 795920 5298148 Tmel_0753 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306001.1 794607 R 391009 CDS YP_001306002.1 150020648 5298104 complement(796144..797802) 1 NC_009616.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 797802 5298104 Tmel_0754 Thermosipho melanesiensis BI429 hydroxylamine reductase YP_001306002.1 796144 R 391009 CDS YP_001306003.1 150020649 5298105 complement(797815..799011) 1 NC_009616.1 PFAM: Hemerythrin HHE cation binding domain protein; hemerythrin HHE cation binding domain-containing protein 799011 5298105 Tmel_0755 Thermosipho melanesiensis BI429 hemerythrin HHE cation binding domain-containing protein YP_001306003.1 797815 R 391009 CDS YP_001306004.1 150020650 5298073 complement(799102..799764) 1 NC_009616.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; CRP/FNR family transcriptional regulator 799764 5298073 Tmel_0756 Thermosipho melanesiensis BI429 CRP/FNR family transcriptional regulator YP_001306004.1 799102 R 391009 CDS YP_001306005.1 150020651 5298074 complement(799803..801527) 1 NC_009616.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/subunit 801527 5298074 Tmel_0757 Thermosipho melanesiensis BI429 phosphoglucomutase/phosphomannomutase alpha/beta/subunit YP_001306005.1 799803 R 391009 CDS YP_001306006.1 150020652 5298450 complement(801532..801903) 1 NC_009616.1 PFAM: CoA-binding domain protein; CoA-binding domain-containing protein 801903 5298450 Tmel_0758 Thermosipho melanesiensis BI429 CoA-binding domain-containing protein YP_001306006.1 801532 R 391009 CDS YP_001306007.1 150020653 5298341 801999..802463 1 NC_009616.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 802463 5298341 Tmel_0759 Thermosipho melanesiensis BI429 alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_001306007.1 801999 D 391009 CDS YP_001306008.1 150020654 5298342 802472..803308 1 NC_009616.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; PhzF family phenazine biosynthesis protein 803308 5298342 Tmel_0760 Thermosipho melanesiensis BI429 PhzF family phenazine biosynthesis protein YP_001306008.1 802472 D 391009 CDS YP_001306009.1 150020655 5298051 complement(803339..804370) 1 NC_009616.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; mandelate racemase/muconate lactonizing protein 804370 5298051 Tmel_0761 Thermosipho melanesiensis BI429 mandelate racemase/muconate lactonizing protein YP_001306009.1 803339 R 391009 CDS YP_001306010.1 150020656 5298052 complement(804383..804991) 1 NC_009616.1 TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15, pyroglutamyl peptidase I; pyrrolidone-carboxylate peptidase 804991 5298052 Tmel_0762 Thermosipho melanesiensis BI429 pyrrolidone-carboxylate peptidase YP_001306010.1 804383 R 391009 CDS YP_001306011.1 150020657 5298307 805155..806117 1 NC_009616.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI 806117 5298307 Tmel_0763 Thermosipho melanesiensis BI429 regulatory protein LacI YP_001306011.1 805155 D 391009 CDS YP_001306012.1 150020658 5298343 806131..807015 1 NC_009616.1 PFAM: glycosidase, PH1107-related; glycosidase 807015 5298343 Tmel_0764 Thermosipho melanesiensis BI429 glycosidase YP_001306012.1 806131 D 391009 CDS YP_001306013.1 150020659 5298344 807020..808444 1 NC_009616.1 PFAM: glycoside hydrolase, family 4; glycoside hydrolase family protein 808444 5298344 Tmel_0765 Thermosipho melanesiensis BI429 glycoside hydrolase family protein YP_001306013.1 807020 D 391009 CDS YP_001306014.1 150020660 5298043 808601..808807 1 NC_009616.1 PFAM: regulatory protein, ArsR; regulatory protein ArsR 808807 5298043 Tmel_0766 Thermosipho melanesiensis BI429 regulatory protein ArsR YP_001306014.1 808601 D 391009 CDS YP_001306015.1 150020661 5298080 809902..810681 1 NC_009616.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 810681 5298080 Tmel_0768 Thermosipho melanesiensis BI429 phosphodiesterase YP_001306015.1 809902 D 391009 CDS YP_001306016.1 150020662 5298311 complement(810678..812333) 1 NC_009616.1 TIGRFAM: DNA mismatch repair protein MutL; PFAM: DNA mismatch repair protein, C-terminal domain protein; MutL, C-terminal, dimerisation; DNA mismatch repair protein MutL 812333 5298311 Tmel_0769 Thermosipho melanesiensis BI429 DNA mismatch repair protein MutL YP_001306016.1 810678 R 391009 CDS YP_001306017.1 150020663 5298056 complement(812334..813701) 1 NC_009616.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 813701 5298056 Tmel_0770 Thermosipho melanesiensis BI429 alpha amylase catalytic subunit YP_001306017.1 812334 R 391009 CDS YP_001306018.1 150020664 5298057 complement(813703..814170) 1 NC_009616.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 814170 5298057 Tmel_0771 Thermosipho melanesiensis BI429 phosphodiesterase YP_001306018.1 813703 R 391009 CDS YP_001306019.1 150020665 5298420 complement(814183..815409) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 815409 5298420 Tmel_0772 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306019.1 814183 R 391009 CDS YP_001306020.1 150020666 5298421 complement(815413..816384) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 816384 5298421 Tmel_0773 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306020.1 815413 R 391009 CDS YP_001306021.1 150020667 5298137 complement(816377..817924) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 817924 5298137 Tmel_0774 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306021.1 816377 R 391009 CDS YP_001306022.1 150020668 5297988 complement(817902..818621) 1 NC_009616.1 hypothetical protein 818621 5297988 Tmel_0775 Thermosipho melanesiensis BI429 hypothetical protein YP_001306022.1 817902 R 391009 CDS YP_001306023.1 150020669 5297989 complement(818634..818930) 1 NC_009616.1 hypothetical protein 818930 5297989 Tmel_0776 Thermosipho melanesiensis BI429 hypothetical protein YP_001306023.1 818634 R 391009 CDS YP_001306024.1 150020670 5298071 complement(818927..819538) 1 NC_009616.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; ECF subfamily RNA polymerase sigma-24 factor 819538 5298071 Tmel_0777 Thermosipho melanesiensis BI429 ECF subfamily RNA polymerase sigma-24 factor YP_001306024.1 818927 R 391009 CDS YP_001306025.1 150020671 5298072 complement(819519..820271) 1 NC_009616.1 PFAM: protein of unknown function DUF72; hypothetical protein 820271 5298072 Tmel_0778 Thermosipho melanesiensis BI429 hypothetical protein YP_001306025.1 819519 R 391009 CDS YP_001306026.1 150020672 5297987 complement(820268..822160) 1 NC_009616.1 PFAM: UvrD/REP helicase; UvrD/REP helicase 822160 5297987 Tmel_0779 Thermosipho melanesiensis BI429 UvrD/REP helicase YP_001306026.1 820268 R 391009 CDS YP_001306027.1 150020673 5298273 complement(822534..822974) 1 NC_009616.1 hypothetical protein 822974 5298273 Tmel_0780 Thermosipho melanesiensis BI429 hypothetical protein YP_001306027.1 822534 R 391009 CDS YP_001306028.1 150020674 5298274 complement(822979..823620) 1 NC_009616.1 hypothetical protein 823620 5298274 Tmel_0781 Thermosipho melanesiensis BI429 hypothetical protein YP_001306028.1 822979 R 391009 CDS YP_001306029.1 150020675 5298402 complement(823633..824616) 1 NC_009616.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI 824616 5298402 Tmel_0782 Thermosipho melanesiensis BI429 regulatory protein LacI YP_001306029.1 823633 R 391009 CDS YP_001306030.1 150020676 5298403 complement(824613..825818) 1 NC_009616.1 TIGRFAM: molybdenum cofactor synthesis domain; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; competence/damage-inducible protein CinA 825818 5298403 Tmel_0783 Thermosipho melanesiensis BI429 competence/damage-inducible protein CinA YP_001306030.1 824613 R 391009 CDS YP_001306031.1 150020677 5298394 825951..827528 1 NC_009616.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 827528 pyrG 5298394 pyrG Thermosipho melanesiensis BI429 CTP synthetase YP_001306031.1 825951 D 391009 CDS YP_001306032.1 150020678 5298364 827525..828247 1 NC_009616.1 TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP C-terminal domain protein; HisJ family histidinol phosphate phosphatase 828247 5298364 Tmel_0785 Thermosipho melanesiensis BI429 HisJ family histidinol phosphate phosphatase YP_001306032.1 827525 D 391009 CDS YP_001306033.1 150020679 5298365 828244..828834 1 NC_009616.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 828834 tsf 5298365 tsf Thermosipho melanesiensis BI429 elongation factor Ts YP_001306033.1 828244 D 391009 CDS YP_001306034.1 150020680 5298053 complement(829042..830112) 1 NC_009616.1 TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; putative PAS/PAC sensor protein 830112 5298053 Tmel_0787 Thermosipho melanesiensis BI429 putative PAS/PAC sensor protein YP_001306034.1 829042 R 391009 CDS YP_001306035.1 150020681 5298054 complement(830117..830755) 1 NC_009616.1 PFAM: protein of unknown function DUF47; hypothetical protein 830755 5298054 Tmel_0788 Thermosipho melanesiensis BI429 hypothetical protein YP_001306035.1 830117 R 391009 CDS YP_001306036.1 150020682 5298109 complement(830775..831701) 1 NC_009616.1 PFAM: phosphate transporter; phosphate transporter 831701 5298109 Tmel_0789 Thermosipho melanesiensis BI429 phosphate transporter YP_001306036.1 830775 R 391009 CDS YP_001306037.1 150020683 5298087 831820..832536 1 NC_009616.1 hypothetical protein 832536 5298087 Tmel_0790 Thermosipho melanesiensis BI429 hypothetical protein YP_001306037.1 831820 D 391009 CDS YP_001306038.1 150020684 5298088 832549..832695 1 NC_009616.1 hypothetical protein 832695 5298088 Tmel_0791 Thermosipho melanesiensis BI429 hypothetical protein YP_001306038.1 832549 D 391009 CDS YP_001306039.1 150020685 5298097 832698..833237 1 NC_009616.1 hypothetical protein 833237 5298097 Tmel_0792 Thermosipho melanesiensis BI429 hypothetical protein YP_001306039.1 832698 D 391009 CDS YP_001306040.1 150020686 5298098 833248..834165 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 834165 5298098 Tmel_0793 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306040.1 833248 D 391009 CDS YP_001306041.1 150020687 5298084 complement(834197..834802) 1 NC_009616.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.; indolepyruvate oxidoreductase subunit beta 834802 5298084 Tmel_0794 Thermosipho melanesiensis BI429 indolepyruvate oxidoreductase subunit beta YP_001306041.1 834197 R 391009 CDS YP_001306042.1 150020688 5298040 complement(834802..836730) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein 836730 5298040 Tmel_0795 Thermosipho melanesiensis BI429 thiamine pyrophosphate binding domain-containing protein YP_001306042.1 834802 R 391009 CDS YP_001306043.1 150020689 5298041 836968..838242 1 NC_009616.1 PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter 838242 5298041 Tmel_0796 Thermosipho melanesiensis BI429 citrate transporter YP_001306043.1 836968 D 391009 CDS YP_001306044.1 150020690 5298230 838245..839318 1 NC_009616.1 PFAM: GTP-binding protein, HSR1-related; HSR1-like GTP-binding protein 839318 5298230 Tmel_0797 Thermosipho melanesiensis BI429 HSR1-like GTP-binding protein YP_001306044.1 838245 D 391009 CDS YP_001306045.1 150020691 5298231 839322..839909 1 NC_009616.1 PFAM: Propanediol utilization protein; propanediol utilization protein 839909 5298231 Tmel_0798 Thermosipho melanesiensis BI429 propanediol utilization protein YP_001306045.1 839322 D 391009 CDS YP_001306046.1 150020692 5298215 840017..840214 1 NC_009616.1 hypothetical protein 840214 5298215 Tmel_0799 Thermosipho melanesiensis BI429 hypothetical protein YP_001306046.1 840017 D 391009 CDS YP_001306047.1 150020693 5298008 840235..840504 1 NC_009616.1 hypothetical protein 840504 5298008 Tmel_0800 Thermosipho melanesiensis BI429 hypothetical protein YP_001306047.1 840235 D 391009 CDS YP_001306048.1 150020694 5298009 840516..840647 1 NC_009616.1 hypothetical protein 840647 5298009 Tmel_0801 Thermosipho melanesiensis BI429 hypothetical protein YP_001306048.1 840516 D 391009 CDS YP_001306049.1 150020695 5298102 complement(840893..844381) 1 NC_009616.1 PFAM: glycoside hydrolase, family 13 domain protein; glycoside hydrolase, family 57; glycoside hydrolase family protein 844381 5298102 Tmel_0803 Thermosipho melanesiensis BI429 glycoside hydrolase family protein YP_001306049.1 840893 R 391009 CDS YP_001306050.1 150020696 5298284 complement(844465..844788) 1 NC_009616.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L; NADH-ubiquinone oxidoreductase subunit 4L 844788 5298284 Tmel_0804 Thermosipho melanesiensis BI429 NADH-ubiquinone oxidoreductase subunit 4L YP_001306050.1 844465 R 391009 CDS YP_001306051.1 150020697 5298099 complement(844782..845987) 1 NC_009616.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH/ubiquinone/plastoquinone (complex I) 845987 5298099 Tmel_0805 Thermosipho melanesiensis BI429 NADH/ubiquinone/plastoquinone (complex I) YP_001306051.1 844782 R 391009 CDS YP_001306052.1 150020698 5298220 complement(846071..847255) 1 NC_009616.1 PFAM: phosphofructokinase; phosphofructokinase 847255 5298220 Tmel_0806 Thermosipho melanesiensis BI429 phosphofructokinase YP_001306052.1 846071 R 391009 CDS YP_001306053.1 150020699 5298221 complement(847321..848460) 1 NC_009616.1 PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 848460 5298221 Tmel_0807 Thermosipho melanesiensis BI429 iron-containing alcohol dehydrogenase YP_001306053.1 847321 R 391009 CDS YP_001306054.1 150020700 5298223 complement(848465..849364) 1 NC_009616.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 849364 era 5298223 era Thermosipho melanesiensis BI429 GTP-binding protein Era YP_001306054.1 848465 R 391009 CDS YP_001306055.1 150020701 5298224 complement(849366..851702) 1 NC_009616.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 851702 pheT 5298224 pheT Thermosipho melanesiensis BI429 phenylalanyl-tRNA synthetase subunit beta YP_001306055.1 849366 R 391009 CDS YP_001306056.1 150020702 5298226 complement(851721..852338) 1 NC_009616.1 hypothetical protein 852338 5298226 Tmel_0810 Thermosipho melanesiensis BI429 hypothetical protein YP_001306056.1 851721 R 391009 CDS YP_001306057.1 150020703 5298227 complement(852340..852759) 1 NC_009616.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Sel1 domain protein repeat-containing protein; Tetratricopeptide domain protein; TPR repeat-containing protein 852759 5298227 Tmel_0811 Thermosipho melanesiensis BI429 TPR repeat-containing protein YP_001306057.1 852340 R 391009 CDS YP_001306058.1 150020704 5298138 complement(852734..854221) 1 NC_009616.1 hypothetical protein 854221 5298138 Tmel_0812 Thermosipho melanesiensis BI429 hypothetical protein YP_001306058.1 852734 R 391009 CDS YP_001306059.1 150020705 5298139 complement(854218..854820) 1 NC_009616.1 PFAM: protein of unknown function DUF205; membrane protein 854820 5298139 Tmel_0813 Thermosipho melanesiensis BI429 membrane protein YP_001306059.1 854218 R 391009 CDS YP_001306060.1 150020706 5298028 complement(854820..855620) 1 NC_009616.1 hypothetical protein 855620 5298028 Tmel_0814 Thermosipho melanesiensis BI429 hypothetical protein YP_001306060.1 854820 R 391009 CDS YP_001306061.1 150020707 5298029 complement(855648..856712) 1 NC_009616.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 856712 5298029 Tmel_0815 Thermosipho melanesiensis BI429 UDP-N-acetylglucosamine 2-epimerase YP_001306061.1 855648 R 391009 CDS YP_001306062.1 150020708 5298066 complement(856715..857788) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 857788 5298066 Tmel_0816 Thermosipho melanesiensis BI429 major facilitator transporter YP_001306062.1 856715 R 391009 CDS YP_001306063.1 150020709 5298067 complement(857791..858096) 1 NC_009616.1 hypothetical protein 858096 5298067 Tmel_0817 Thermosipho melanesiensis BI429 hypothetical protein YP_001306063.1 857791 R 391009 CDS YP_001306064.1 150020710 5298119 858286..859533 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 859533 5298119 Tmel_0818 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306064.1 858286 D 391009 CDS YP_001306065.1 150020711 5298120 859570..860490 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 860490 5298120 Tmel_0819 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306065.1 859570 D 391009 CDS YP_001306066.1 150020712 5298173 860487..861296 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 861296 5298173 Tmel_0820 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306066.1 860487 D 391009 CDS YP_001306067.1 150020713 5298174 861330..862532 1 NC_009616.1 putative diguanylate cyclase 862532 5298174 Tmel_0821 Thermosipho melanesiensis BI429 putative diguanylate cyclase YP_001306067.1 861330 D 391009 CDS YP_001306068.1 150020714 5298216 862593..862892 1 NC_009616.1 PFAM: GGDEF domain containing protein; diguanylate cyclase 862892 5298216 Tmel_0822 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306068.1 862593 D 391009 CDS YP_001306069.1 150020715 5298217 complement(862893..863987) 1 NC_009616.1 hypothetical protein 863987 5298217 Tmel_0823 Thermosipho melanesiensis BI429 hypothetical protein YP_001306069.1 862893 R 391009 CDS YP_001306070.1 150020716 5298288 complement(864007..865881) 1 NC_009616.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 865881 5298288 Tmel_0824 Thermosipho melanesiensis BI429 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001306070.1 864007 R 391009 CDS YP_001306071.1 150020717 5298289 complement(866080..867420) 1 NC_009616.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; dihydrolipoamide dehydrogenase 867420 5298289 Tmel_0825 Thermosipho melanesiensis BI429 dihydrolipoamide dehydrogenase YP_001306071.1 866080 R 391009 CDS YP_001306072.1 150020718 5298193 complement(867478..868149) 1 NC_009616.1 PFAM: sugar fermentation stimulation protein; sugar fermentation stimulation protein 868149 5298193 Tmel_0826 Thermosipho melanesiensis BI429 sugar fermentation stimulation protein YP_001306072.1 867478 R 391009 CDS YP_001306073.1 150020719 5298194 complement(868194..868430) 1 NC_009616.1 TIGRFAM: redox-active disulfide protein 2; redox-active disulfide protein 2 868430 5298194 Tmel_0827 Thermosipho melanesiensis BI429 redox-active disulfide protein 2 YP_001306073.1 868194 R 391009 CDS YP_001306074.1 150020720 5298202 complement(868442..869527) 1 NC_009616.1 PFAM: permease; permease 869527 5298202 Tmel_0828 Thermosipho melanesiensis BI429 permease YP_001306074.1 868442 R 391009 CDS YP_001306075.1 150020721 5298203 complement(869604..869867) 1 NC_009616.1 PFAM: regulatory protein, ArsR; regulatory protein ArsR 869867 5298203 Tmel_0829 Thermosipho melanesiensis BI429 regulatory protein ArsR YP_001306075.1 869604 R 391009 CDS YP_001306076.1 150020722 5297996 869976..871313 1 NC_009616.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; MATE efflux family protein 871313 5297996 Tmel_0830 Thermosipho melanesiensis BI429 MATE efflux family protein YP_001306076.1 869976 D 391009 CDS YP_001306077.1 150020723 5297997 complement(871310..873043) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 873043 5297997 Tmel_0831 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306077.1 871310 R 391009 CDS YP_001306078.1 150020724 5298130 complement(873049..873453) 1 NC_009616.1 hypothetical protein 873453 5298130 Tmel_0832 Thermosipho melanesiensis BI429 hypothetical protein YP_001306078.1 873049 R 391009 CDS YP_001306079.1 150020725 5298131 complement(873957..874250) 1 NC_009616.1 hypothetical protein 874250 5298131 Tmel_0833 Thermosipho melanesiensis BI429 hypothetical protein YP_001306079.1 873957 R 391009 CDS YP_001306080.1 150020726 5298263 874535..875347 1 NC_009616.1 PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 875347 5298263 Tmel_0834 Thermosipho melanesiensis BI429 cobyrinic acid a,c-diamide synthase YP_001306080.1 874535 D 391009 CDS YP_001306081.1 150020727 5298264 875503..875967 1 NC_009616.1 PFAM: protein of unknown function DUF327; hypothetical protein 875967 5298264 Tmel_0835 Thermosipho melanesiensis BI429 hypothetical protein YP_001306081.1 875503 D 391009 CDS YP_001306082.1 150020728 5297993 875979..876746 1 NC_009616.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 876746 5297993 Tmel_0836 Thermosipho melanesiensis BI429 stationary phase survival protein SurE YP_001306082.1 875979 D 391009 CDS YP_001306083.1 150020729 5297994 876724..877221 1 NC_009616.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 877221 5297994 Tmel_0837 Thermosipho melanesiensis BI429 peptide deformylase YP_001306083.1 876724 D 391009 CDS YP_001306084.1 150020730 5298337 877218..878762 1 NC_009616.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; DEAD/DEAH box helicase domain-containing protein 878762 5298337 Tmel_0838 Thermosipho melanesiensis BI429 DEAD/DEAH box helicase domain-containing protein YP_001306084.1 877218 D 391009 CDS YP_001306085.1 150020731 5298338 878773..879258 1 NC_009616.1 PFAM: outer membrane chaperone Skp (OmpH); outer membrane chaperone Skp 879258 5298338 Tmel_0839 Thermosipho melanesiensis BI429 outer membrane chaperone Skp YP_001306085.1 878773 D 391009 CDS YP_001306086.1 150020732 5298349 879255..879950 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 879950 5298349 Tmel_0840 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306086.1 879255 D 391009 CDS YP_001306087.1 150020733 5298350 879952..880686 1 NC_009616.1 hypothetical protein 880686 5298350 Tmel_0841 Thermosipho melanesiensis BI429 hypothetical protein YP_001306087.1 879952 D 391009 CDS YP_001306088.1 150020734 5298362 880679..881269 1 NC_009616.1 hypothetical protein 881269 5298362 Tmel_0842 Thermosipho melanesiensis BI429 hypothetical protein YP_001306088.1 880679 D 391009 CDS YP_001306089.1 150020735 5298363 881273..881641 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 881641 5298363 Tmel_0843 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001306089.1 881273 D 391009 CDS YP_001306090.1 150020736 5298368 881634..882998 1 NC_009616.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; stage II sporulation E family protein 882998 5298368 Tmel_0844 Thermosipho melanesiensis BI429 stage II sporulation E family protein YP_001306090.1 881634 D 391009 CDS YP_001306091.1 150020737 5298369 883010..883567 1 NC_009616.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 883567 5298369 Tmel_0845 Thermosipho melanesiensis BI429 elongation factor P YP_001306091.1 883010 D 391009 CDS YP_001306092.1 150020738 5298404 883583..883918 1 NC_009616.1 PFAM: protein of unknown function DUF322; hypothetical protein 883918 5298404 Tmel_0846 Thermosipho melanesiensis BI429 hypothetical protein YP_001306092.1 883583 D 391009 CDS YP_001306093.1 150020739 5298405 883919..884344 1 NC_009616.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 884344 nusB 5298405 nusB Thermosipho melanesiensis BI429 transcription antitermination protein NusB YP_001306093.1 883919 D 391009 CDS YP_001306094.1 150020740 5298121 884423..884815 1 NC_009616.1 hypothetical protein 884815 5298121 Tmel_0848 Thermosipho melanesiensis BI429 hypothetical protein YP_001306094.1 884423 D 391009 CDS YP_001306095.1 150020741 5298122 complement(884801..885934) 1 NC_009616.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; flagellar biosynthetic protein FlhB 885934 5298122 Tmel_0849 Thermosipho melanesiensis BI429 flagellar biosynthetic protein FlhB YP_001306095.1 884801 R 391009 CDS YP_001306096.1 150020742 5298000 complement(885865..886629) 1 NC_009616.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; flagellar biosynthetic protein FliR 886629 5298000 Tmel_0850 Thermosipho melanesiensis BI429 flagellar biosynthetic protein FliR YP_001306096.1 885865 R 391009 CDS YP_001306097.1 150020743 5298001 complement(886629..888926) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 888926 5298001 Tmel_0851 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001306097.1 886629 R 391009 CDS YP_001306098.1 150020744 5298281 complement(888940..889761) 1 NC_009616.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 889761 5298281 Tmel_0852 Thermosipho melanesiensis BI429 purine nucleoside phosphorylase YP_001306098.1 888940 R 391009 CDS YP_001306099.1 150020745 5298282 complement(889800..891275) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 891275 5298282 Tmel_0853 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306099.1 889800 R 391009 CDS YP_001306100.1 150020746 5298103 891674..892633 1 NC_009616.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 892633 5298103 Tmel_0854 Thermosipho melanesiensis BI429 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001306100.1 891674 D 391009 CDS YP_001306101.1 150020747 5298049 892605..893102 1 NC_009616.1 PFAM: cobalbumin biosynthesis enzyme; cobalbumin biosynthesis protein 893102 5298049 Tmel_0855 Thermosipho melanesiensis BI429 cobalbumin biosynthesis protein YP_001306101.1 892605 D 391009 CDS YP_001306102.1 150020748 5298100 893099..893716 1 NC_009616.1 hypothetical protein 893716 5298100 Tmel_0856 Thermosipho melanesiensis BI429 hypothetical protein YP_001306102.1 893099 D 391009 CDS YP_001306103.1 150020749 5298101 893706..894404 1 NC_009616.1 PFAM: cobalamin-5-phosphate synthase CobS; cobalamin-5-phosphate synthase CobS 894404 5298101 Tmel_0857 Thermosipho melanesiensis BI429 cobalamin-5-phosphate synthase CobS YP_001306103.1 893706 D 391009 CDS YP_001306104.1 150020750 5298390 894404..895801 1 NC_009616.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; cobyric acid synthase CobQ 895801 5298390 Tmel_0858 Thermosipho melanesiensis BI429 cobyric acid synthase CobQ YP_001306104.1 894404 D 391009 CDS YP_001306105.1 150020751 5298391 895785..896621 1 NC_009616.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; cobalamin biosynthesis protein CobD 896621 5298391 Tmel_0859 Thermosipho melanesiensis BI429 cobalamin biosynthesis protein CobD YP_001306105.1 895785 D 391009 CDS YP_001306106.1 150020752 5298290 896570..897541 1 NC_009616.1 PFAM: aminotransferase, class I and II; putative aminotransferase 897541 5298290 Tmel_0860 Thermosipho melanesiensis BI429 putative aminotransferase YP_001306106.1 896570 D 391009 CDS YP_001306107.1 150020753 5298291 897538..898035 1 NC_009616.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 898035 5298291 Tmel_0861 Thermosipho melanesiensis BI429 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001306107.1 897538 D 391009 CDS YP_001306108.1 150020754 5298297 898193..899866 1 NC_009616.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 899866 5298297 Tmel_0862 Thermosipho melanesiensis BI429 peptidase S8/S53 subtilisin kexin sedolisin YP_001306108.1 898193 D 391009 CDS YP_001306109.1 150020755 5298298 complement(899941..900231) 1 NC_009616.1 hypothetical protein 900231 5298298 Tmel_0863 Thermosipho melanesiensis BI429 hypothetical protein YP_001306109.1 899941 R 391009 CDS YP_001306110.1 150020756 5298436 complement(900231..900896) 1 NC_009616.1 SARP family transcriptional regulator 900896 5298436 Tmel_0864 Thermosipho melanesiensis BI429 SARP family transcriptional regulator YP_001306110.1 900231 R 391009 CDS YP_001306111.1 150020757 5298437 complement(900936..901448) 1 NC_009616.1 response regulator receiver/SARP domain-containing protein 901448 5298437 Tmel_0865 Thermosipho melanesiensis BI429 response regulator receiver/SARP domain-containing protein YP_001306111.1 900936 R 391009 CDS YP_001306112.1 150020758 5298438 complement(901732..902748) 1 NC_009616.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 902748 glpX 5298438 glpX Thermosipho melanesiensis BI429 fructose 1,6-bisphosphatase II YP_001306112.1 901732 R 391009 CDS YP_001306113.1 150020759 5298439 complement(902864..903556) 1 NC_009616.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RNA-binding S4 domain-containing protein 903556 5298439 Tmel_0867 Thermosipho melanesiensis BI429 RNA-binding S4 domain-containing protein YP_001306113.1 902864 R 391009 CDS YP_001306114.1 150020760 5298445 complement(903543..904343) 1 NC_009616.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS; dihydropteroate synthase 904343 5298445 Tmel_0868 Thermosipho melanesiensis BI429 dihydropteroate synthase YP_001306114.1 903543 R 391009 CDS YP_001306115.1 150020761 5298446 904437..905210 1 NC_009616.1 esterase/lipase-like protein 905210 5298446 Tmel_0869 Thermosipho melanesiensis BI429 esterase/lipase-like protein YP_001306115.1 904437 D 391009 CDS YP_001306116.1 150020762 5298124 905251..906267 1 NC_009616.1 PFAM: aminotransferase, class V; class V aminotransferase 906267 5298124 Tmel_0870 Thermosipho melanesiensis BI429 class V aminotransferase YP_001306116.1 905251 D 391009 CDS YP_001306117.1 150020763 5298125 906264..906962 1 NC_009616.1 sugar nucleotidyltransferase-like protein 906962 5298125 Tmel_0871 Thermosipho melanesiensis BI429 sugar nucleotidyltransferase-like protein YP_001306117.1 906264 D 391009 CDS YP_001306118.1 150020764 5298169 906983..907618 1 NC_009616.1 PFAM: CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 907618 5298169 Tmel_0872 Thermosipho melanesiensis BI429 CDP-alcohol phosphatidyltransferase YP_001306118.1 906983 D 391009 CDS YP_001306119.1 150020765 5298170 907615..908580 1 NC_009616.1 PFAM: conserved hypothetical protein 374; hypothetical protein 908580 5298170 Tmel_0873 Thermosipho melanesiensis BI429 hypothetical protein YP_001306119.1 907615 D 391009 CDS YP_001306120.1 150020766 5298036 complement(908581..909933) 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 909933 5298036 Tmel_0874 Thermosipho melanesiensis BI429 major facilitator transporter YP_001306120.1 908581 R 391009 CDS YP_001306121.1 150020767 5298037 complement(909930..911261) 1 NC_009616.1 PFAM: protein of unknown function UPF0027; hypothetical protein 911261 5298037 Tmel_0875 Thermosipho melanesiensis BI429 hypothetical protein YP_001306121.1 909930 R 391009 CDS YP_001306122.1 150020768 5298095 complement(911265..911921) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 911921 5298095 Tmel_0876 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306122.1 911265 R 391009 CDS YP_001306123.1 150020769 5298096 complement(911912..912637) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 912637 5298096 Tmel_0877 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306123.1 911912 R 391009 CDS YP_001306124.1 150020770 5298175 complement(912634..913533) 1 NC_009616.1 nitrate/sulfonate/bicarbonate ABC transporter periplasmic components-like protein 913533 5298175 Tmel_0878 Thermosipho melanesiensis BI429 nitrate/sulfonate/bicarbonate ABC transporter periplasmic components-like protein YP_001306124.1 912634 R 391009 CDS YP_001306125.1 150020771 5298415 complement(913696..914019) 1 NC_009616.1 hypothetical protein 914019 5298415 Tmel_0879 Thermosipho melanesiensis BI429 hypothetical protein YP_001306125.1 913696 R 391009 CDS YP_001306126.1 150020772 5298316 complement(914089..915252) 1 NC_009616.1 hypothetical protein 915252 5298316 Tmel_0880 Thermosipho melanesiensis BI429 hypothetical protein YP_001306126.1 914089 R 391009 CDS YP_001306127.1 150020773 5298317 complement(915255..917726) 1 NC_009616.1 hypothetical protein 917726 5298317 Tmel_0881 Thermosipho melanesiensis BI429 hypothetical protein YP_001306127.1 915255 R 391009 CDS YP_001306128.1 150020774 5298140 complement(917745..918749) 1 NC_009616.1 PFAM: protein of unknown function UPF0118; hypothetical protein 918749 5298140 Tmel_0882 Thermosipho melanesiensis BI429 hypothetical protein YP_001306128.1 917745 R 391009 CDS YP_001306129.1 150020775 5298141 complement(918739..919743) 1 NC_009616.1 PFAM: Asparaginase/glutaminase; asparaginase/glutaminase 919743 5298141 Tmel_0883 Thermosipho melanesiensis BI429 asparaginase/glutaminase YP_001306129.1 918739 R 391009 CDS YP_001306130.1 150020776 5298321 complement(919740..920441) 1 NC_009616.1 PFAM: Rhomboid family protein; rhomboid family protein 920441 5298321 Tmel_0884 Thermosipho melanesiensis BI429 rhomboid family protein YP_001306130.1 919740 R 391009 CDS YP_001306131.1 150020777 5298322 complement(920457..920567) 1 NC_009616.1 hypothetical protein 920567 5298322 Tmel_0885 Thermosipho melanesiensis BI429 hypothetical protein YP_001306131.1 920457 R 391009 CDS YP_001306132.1 150020778 5298162 complement(920569..921279) 1 NC_009616.1 PFAM: protein of unknown function DUF218; hypothetical protein 921279 5298162 Tmel_0886 Thermosipho melanesiensis BI429 hypothetical protein YP_001306132.1 920569 R 391009 CDS YP_001306133.1 150020779 5298163 complement(921276..921707) 1 NC_009616.1 TIGRFAM: flagellar export protein FliJ; flagellar export protein FliJ 921707 5298163 Tmel_0887 Thermosipho melanesiensis BI429 flagellar export protein FliJ YP_001306133.1 921276 R 391009 CDS YP_001306134.1 150020780 5298318 complement(921697..922932) 1 NC_009616.1 hypothetical protein 922932 5298318 Tmel_0888 Thermosipho melanesiensis BI429 hypothetical protein YP_001306134.1 921697 R 391009 CDS YP_001306135.1 150020781 5298319 complement(922929..926390) 1 NC_009616.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; RepA / Rep+ KID repeat-containing protein; SMCs flexible hinge domain protein; chromosome segregation protein SMC 926390 5298319 Tmel_0889 Thermosipho melanesiensis BI429 chromosome segregation protein SMC YP_001306135.1 922929 R 391009 CDS YP_001306136.1 150020782 5297887 complement(926387..927682) 1 NC_009616.1 TIGRFAM: UDP-N-acetylmuramate--alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramate--alanine ligase 927682 5297887 Tmel_0890 Thermosipho melanesiensis BI429 UDP-N-acetylmuramate--alanine ligase YP_001306136.1 926387 R 391009 CDS YP_001306137.1 150020783 5297888 complement(927679..928683) 1 NC_009616.1 PFAM: glycosyl transferase, family 28; Glycosyltransferase 28, C-terminal domain; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 928683 5297888 Tmel_0891 Thermosipho melanesiensis BI429 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_001306137.1 927679 R 391009 CDS YP_001306138.1 150020784 5298128 complement(928676..929632) 1 NC_009616.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 929632 5298128 Tmel_0892 Thermosipho melanesiensis BI429 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_001306138.1 928676 R 391009 CDS YP_001306139.1 150020785 5298129 929767..930477 1 NC_009616.1 PFAM: nitroreductase; nitroreductase 930477 5298129 Tmel_0893 Thermosipho melanesiensis BI429 nitroreductase YP_001306139.1 929767 D 391009 CDS YP_001306140.1 150020786 5297682 930491..932956 1 NC_009616.1 hypothetical protein 932956 5297682 Tmel_0894 Thermosipho melanesiensis BI429 hypothetical protein YP_001306140.1 930491 D 391009 CDS YP_001306141.1 150020787 5297683 932969..934675 1 NC_009616.1 PFAM: FG-GAP repeat protein; FG-GAP repeat-containing protein 934675 5297683 Tmel_0895 Thermosipho melanesiensis BI429 FG-GAP repeat-containing protein YP_001306141.1 932969 D 391009 CDS YP_001306142.1 150020788 5297885 934677..935066 1 NC_009616.1 hypothetical protein 935066 5297885 Tmel_0896 Thermosipho melanesiensis BI429 hypothetical protein YP_001306142.1 934677 D 391009 CDS YP_001306143.1 150020789 5297886 935060..935548 1 NC_009616.1 hypothetical protein 935548 5297886 Tmel_0897 Thermosipho melanesiensis BI429 hypothetical protein YP_001306143.1 935060 D 391009 CDS YP_001306144.1 150020790 5298020 935553..936554 1 NC_009616.1 hypothetical protein 936554 5298020 Tmel_0898 Thermosipho melanesiensis BI429 hypothetical protein YP_001306144.1 935553 D 391009 CDS YP_001306145.1 150020791 5298021 936566..937003 1 NC_009616.1 hypothetical protein 937003 5298021 Tmel_0899 Thermosipho melanesiensis BI429 hypothetical protein YP_001306145.1 936566 D 391009 CDS YP_001306146.1 150020792 5297974 complement(937000..937590) 1 NC_009616.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase 937590 5297974 Tmel_0900 Thermosipho melanesiensis BI429 HAD family hydrolase YP_001306146.1 937000 R 391009 CDS YP_001306147.1 150020793 5297975 complement(937563..939494) 1 NC_009616.1 TIGRFAM: putative DNA helicase; SMART: DEAD-like helicases-like; putative DNA helicase 939494 5297975 Tmel_0901 Thermosipho melanesiensis BI429 putative DNA helicase YP_001306147.1 937563 R 391009 CDS YP_001306148.1 150020794 5298134 939600..939872 1 NC_009616.1 hypothetical protein 939872 5298134 Tmel_0902 Thermosipho melanesiensis BI429 hypothetical protein YP_001306148.1 939600 D 391009 CDS YP_001306149.1 150020795 5298135 939901..940503 1 NC_009616.1 hypothetical protein 940503 5298135 Tmel_0903 Thermosipho melanesiensis BI429 hypothetical protein YP_001306149.1 939901 D 391009 CDS YP_001306150.1 150020796 5297419 complement(940541..942535) 1 NC_009616.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; Acetyl xylan esterase; peptidase S9 prolyl oligopeptidase 942535 5297419 Tmel_0904 Thermosipho melanesiensis BI429 peptidase S9 prolyl oligopeptidase YP_001306150.1 940541 R 391009 CDS YP_001306151.1 150020797 5297420 942880..943929 1 NC_009616.1 PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 943929 5297420 Tmel_0905 Thermosipho melanesiensis BI429 dihydrodipicolinate reductase YP_001306151.1 942880 D 391009 CDS YP_001306152.1 150020798 5296764 943939..944247 1 NC_009616.1 hypothetical protein 944247 5296764 Tmel_0906 Thermosipho melanesiensis BI429 hypothetical protein YP_001306152.1 943939 D 391009 CDS YP_001306153.1 150020799 5296765 944240..945658 1 NC_009616.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta 945658 5296765 Tmel_0907 Thermosipho melanesiensis BI429 pyridoxal-5'-phosphate-dependent enzyme subunit beta YP_001306153.1 944240 D 391009 CDS YP_001306154.1 150020800 5297205 945660..946034 1 NC_009616.1 hypothetical protein 946034 5297205 Tmel_0908 Thermosipho melanesiensis BI429 hypothetical protein YP_001306154.1 945660 D 391009 CDS YP_001306155.1 150020801 5297206 946027..948213 1 NC_009616.1 PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 948213 5297206 Tmel_0909 Thermosipho melanesiensis BI429 cobalamin B12-binding domain-containing protein YP_001306155.1 946027 D 391009 CDS YP_001306156.1 150020802 5297658 948285..949040 1 NC_009616.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; TatD family hydrolase 949040 5297658 Tmel_0910 Thermosipho melanesiensis BI429 TatD family hydrolase YP_001306156.1 948285 D 391009 CDS YP_001306157.1 150020803 5297659 949037..949606 1 NC_009616.1 TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: helix-hairpin-helix motif; RuvA domain protein; DNA recombination protein RuvA, domain I; SMART: Helix-hairpin-helix DNA-binding, class 1; Holliday junction DNA helicase RuvA 949606 5297659 Tmel_0911 Thermosipho melanesiensis BI429 Holliday junction DNA helicase RuvA YP_001306157.1 949037 D 391009 CDS YP_001306158.1 150020804 5297865 949611..950090 1 NC_009616.1 hypothetical protein 950090 5297865 Tmel_0912 Thermosipho melanesiensis BI429 hypothetical protein YP_001306158.1 949611 D 391009 CDS YP_001306159.1 150020805 5297866 950104..950433 1 NC_009616.1 hypothetical protein 950433 5297866 Tmel_0913 Thermosipho melanesiensis BI429 hypothetical protein YP_001306159.1 950104 D 391009 CDS YP_001306160.1 150020806 5296802 950430..951128 1 NC_009616.1 PFAM: PHP C-terminal domain protein; phosphotransferase domain-containing protein 951128 5296802 Tmel_0914 Thermosipho melanesiensis BI429 phosphotransferase domain-containing protein YP_001306160.1 950430 D 391009 CDS YP_001306161.1 150020807 5296803 951116..951646 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase 951646 5296803 Tmel_0915 Thermosipho melanesiensis BI429 histidine kinase YP_001306161.1 951116 D 391009 CDS YP_001306162.1 150020808 5296489 951649..953832 1 NC_009616.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; surface antigen 953832 5296489 Tmel_0916 Thermosipho melanesiensis BI429 surface antigen YP_001306162.1 951649 D 391009 CDS YP_001306163.1 150020809 5296490 953847..954938 1 NC_009616.1 PFAM: Threonyl/alanyl tRNA synthetase, SAD; threonyl/alanyl tRNA synthetase 954938 5296490 Tmel_0917 Thermosipho melanesiensis BI429 threonyl/alanyl tRNA synthetase YP_001306163.1 953847 D 391009 CDS YP_001306164.1 150020810 5297960 954935..956134 1 NC_009616.1 hypothetical protein 956134 5297960 Tmel_0918 Thermosipho melanesiensis BI429 hypothetical protein YP_001306164.1 954935 D 391009 CDS YP_001306165.1 150020811 5297961 956219..957100 1 NC_009616.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RluA family pseudouridine synthase 957100 5297961 Tmel_0919 Thermosipho melanesiensis BI429 RluA family pseudouridine synthase YP_001306165.1 956219 D 391009 CDS YP_001306166.1 150020812 5297792 957102..958319 1 NC_009616.1 hypothetical protein 958319 5297792 Tmel_0920 Thermosipho melanesiensis BI429 hypothetical protein YP_001306166.1 957102 D 391009 CDS YP_001306167.1 150020813 5297793 958282..959559 1 NC_009616.1 hypothetical protein 959559 5297793 Tmel_0921 Thermosipho melanesiensis BI429 hypothetical protein YP_001306167.1 958282 D 391009 CDS YP_001306168.1 150020814 5297701 959516..960928 1 NC_009616.1 TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; pyruvate kinase 960928 5297701 Tmel_0922 Thermosipho melanesiensis BI429 pyruvate kinase YP_001306168.1 959516 D 391009 CDS YP_001306169.1 150020815 5297980 961484..961909 1 NC_009616.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 961909 infC 5297980 infC Thermosipho melanesiensis BI429 translation initiation factor IF-3 YP_001306169.1 961484 D 391009 CDS YP_001306170.1 150020816 5296775 961906..962124 1 NC_009616.1 PFAM: ribosomal protein L35; 50S ribosomal protein L35 962124 rpmI 5296775 rpmI Thermosipho melanesiensis BI429 50S ribosomal protein L35 YP_001306170.1 961906 D 391009 CDS YP_001306171.1 150020817 5296776 962152..962508 1 NC_009616.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 962508 rplT 5296776 rplT Thermosipho melanesiensis BI429 50S ribosomal protein L20 YP_001306171.1 962152 D 391009 CDS YP_001306172.1 150020818 5297001 962602..963375 1 NC_009616.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 963375 rpsB 5297001 rpsB Thermosipho melanesiensis BI429 30S ribosomal protein S2 YP_001306172.1 962602 D 391009 CDS YP_001306173.1 150020819 5297002 963416..964015 1 NC_009616.1 PFAM: thymidylate kinase; dTMP kinase 964015 5297002 Tmel_0927 Thermosipho melanesiensis BI429 dTMP kinase YP_001306173.1 963416 D 391009 CDS YP_001306174.1 150020820 5297219 complement(964004..964270) 1 NC_009616.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; flagellar biosynthetic protein FliQ 964270 5297219 Tmel_0928 Thermosipho melanesiensis BI429 flagellar biosynthetic protein FliQ YP_001306174.1 964004 R 391009 CDS YP_001306175.1 150020821 5297220 complement(964273..965028) 1 NC_009616.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 965028 fliP 5297220 fliP Thermosipho melanesiensis BI429 flagellar biosynthesis protein FliP YP_001306175.1 964273 R 391009 CDS YP_001306176.1 150020822 5297949 complement(965025..965291) 1 NC_009616.1 hypothetical protein 965291 5297949 Tmel_0930 Thermosipho melanesiensis BI429 hypothetical protein YP_001306176.1 965025 R 391009 CDS YP_001306177.1 150020823 5297950 complement(965354..965716) 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 965716 5297950 Tmel_0931 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001306177.1 965354 R 391009 CDS YP_001306178.1 150020824 5297217 complement(965721..966176) 1 NC_009616.1 PFAM: CheW domain protein; putative CheW protein 966176 5297217 Tmel_0932 Thermosipho melanesiensis BI429 putative CheW protein YP_001306178.1 965721 R 391009 CDS YP_001306179.1 150020825 5297218 complement(966187..968211) 1 NC_009616.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein; CheA signal transduction histidine kinase 968211 5297218 Tmel_0933 Thermosipho melanesiensis BI429 CheA signal transduction histidine kinase YP_001306179.1 966187 R 391009 CDS YP_001306180.1 150020826 5297840 complement(968224..969615) 1 NC_009616.1 hypothetical protein 969615 5297840 Tmel_0934 Thermosipho melanesiensis BI429 hypothetical protein YP_001306180.1 968224 R 391009 CDS YP_001306181.1 150020827 5297841 complement(969612..970406) 1 NC_009616.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; hemolysin A 970406 5297841 Tmel_0935 Thermosipho melanesiensis BI429 hemolysin A YP_001306181.1 969612 R 391009 CDS YP_001306182.1 150020828 5297768 complement(970403..971626) 1 NC_009616.1 hypothetical protein 971626 5297768 Tmel_0936 Thermosipho melanesiensis BI429 hypothetical protein YP_001306182.1 970403 R 391009 CDS YP_001306183.1 150020829 5297769 complement(971626..972360) 1 NC_009616.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase ACD 972360 5297769 Tmel_0937 Thermosipho melanesiensis BI429 tRNA pseudouridine synthase ACD YP_001306183.1 971626 R 391009 CDS YP_001306184.1 150020830 5297595 complement(972357..973982) 1 NC_009616.1 SMART: GGDEF domain containing protein; diguanylate cyclase 973982 5297595 Tmel_0938 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306184.1 972357 R 391009 CDS YP_001306185.1 150020831 5297596 complement(974108..975301) 1 NC_009616.1 hypothetical protein 975301 5297596 Tmel_0939 Thermosipho melanesiensis BI429 hypothetical protein YP_001306185.1 974108 R 391009 CDS YP_001306186.1 150020832 5296523 complement(975298..976479) 1 NC_009616.1 PFAM: protein of unknown function DUF58; hypothetical protein 976479 5296523 Tmel_0940 Thermosipho melanesiensis BI429 hypothetical protein YP_001306186.1 975298 R 391009 CDS YP_001306187.1 150020833 5296524 complement(976479..977405) 1 NC_009616.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; ATPase 977405 5296524 Tmel_0941 Thermosipho melanesiensis BI429 ATPase YP_001306187.1 976479 R 391009 CDS YP_001306188.1 150020834 5297918 complement(977449..977655) 1 NC_009616.1 hypothetical protein 977655 5297918 Tmel_0942 Thermosipho melanesiensis BI429 hypothetical protein YP_001306188.1 977449 R 391009 CDS YP_001306189.1 150020835 5297919 complement(977687..978775) 1 NC_009616.1 PFAM: cell cycle protein; cell cycle protein 978775 5297919 Tmel_0943 Thermosipho melanesiensis BI429 cell cycle protein YP_001306189.1 977687 R 391009 CDS YP_001306190.1 150020836 5297391 complement(978765..979892) 1 NC_009616.1 TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; putative oxygen-independent coproporphyrinogen III oxidase 979892 5297391 Tmel_0944 Thermosipho melanesiensis BI429 putative oxygen-independent coproporphyrinogen III oxidase YP_001306190.1 978765 R 391009 CDS YP_001306191.1 150020837 5297392 complement(979861..980574) 1 NC_009616.1 hypothetical protein 980574 5297392 Tmel_0945 Thermosipho melanesiensis BI429 hypothetical protein YP_001306191.1 979861 R 391009 CDS YP_001306192.1 150020838 5297094 complement(980785..982215) 1 NC_009616.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 982215 gatB 5297094 gatB Thermosipho melanesiensis BI429 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001306192.1 980785 R 391009 CDS YP_001306193.1 150020839 5297095 complement(982212..983585) 1 NC_009616.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 983585 gatA 5297095 gatA Thermosipho melanesiensis BI429 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001306193.1 982212 R 391009 CDS YP_001306194.1 150020840 5297674 984053..984427 1 NC_009616.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 984427 rpsL 5297674 rpsL Thermosipho melanesiensis BI429 30S ribosomal protein S12 YP_001306194.1 984053 D 391009 CDS YP_001306195.1 150020841 5297222 984446..984913 1 NC_009616.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 984913 5297222 Tmel_0949 Thermosipho melanesiensis BI429 30S ribosomal protein S7 YP_001306195.1 984446 D 391009 CDS YP_001306196.1 150020842 5297568 984927..987002 1 NC_009616.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 987002 5297568 Tmel_0950 Thermosipho melanesiensis BI429 elongation factor G YP_001306196.1 984927 D 391009 CDS YP_001306197.1 150020843 5297569 987037..988239 1 NC_009616.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 988239 5297569 Tmel_0951 Thermosipho melanesiensis BI429 elongation factor Tu YP_001306197.1 987037 D 391009 CDS YP_001306198.1 150020844 5296942 988302..988610 1 NC_009616.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 988610 rpsJ 5296942 rpsJ Thermosipho melanesiensis BI429 30S ribosomal protein S10 YP_001306198.1 988302 D 391009 CDS YP_001306199.1 150020845 5296943 988633..989250 1 NC_009616.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 989250 rplC 5296943 rplC Thermosipho melanesiensis BI429 50S ribosomal protein L3 YP_001306199.1 988633 D 391009 CDS YP_001306200.1 150020846 5296854 989288..989953 1 NC_009616.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 989953 rplD 5296854 rplD Thermosipho melanesiensis BI429 50S ribosomal protein L4 YP_001306200.1 989288 D 391009 CDS YP_001306201.1 150020847 5296855 989953..990258 1 NC_009616.1 PFAM: Ribosomal protein L25/L23; ribosomal protein L25/L23 990258 5296855 Tmel_0955 Thermosipho melanesiensis BI429 ribosomal protein L25/L23 YP_001306201.1 989953 D 391009 CDS YP_001306202.1 150020848 5296800 990274..991098 1 NC_009616.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 991098 rplB 5296800 rplB Thermosipho melanesiensis BI429 50S ribosomal protein L2 YP_001306202.1 990274 D 391009 CDS YP_001306203.1 150020849 5296801 991114..991401 1 NC_009616.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 991401 rpsS 5296801 rpsS Thermosipho melanesiensis BI429 30S ribosomal protein S19 YP_001306203.1 991114 D 391009 CDS YP_001306204.1 150020850 5297372 991416..991865 1 NC_009616.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 991865 rplV 5297372 rplV Thermosipho melanesiensis BI429 50S ribosomal protein L22 YP_001306204.1 991416 D 391009 CDS YP_001306205.1 150020851 5297373 991883..992512 1 NC_009616.1 TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3-C-terminal domain protein; KH, type 2 domain protein; Ribosomal protein S3, N-terminal domain; SMART: KH domain protein; ribosomal protein S3 992512 5297373 Tmel_0959 Thermosipho melanesiensis BI429 ribosomal protein S3 YP_001306205.1 991883 D 391009 CDS YP_001306206.1 150020852 5297910 992535..992963 1 NC_009616.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 992963 rplP 5297910 rplP Thermosipho melanesiensis BI429 50S ribosomal protein L16 YP_001306206.1 992535 D 391009 CDS YP_001306207.1 150020853 5297911 992960..993160 1 NC_009616.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 993160 5297911 Tmel_0961 Thermosipho melanesiensis BI429 50S ribosomal protein L29 YP_001306207.1 992960 D 391009 CDS YP_001306208.1 150020854 5297826 993166..993465 1 NC_009616.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 993465 rpsQ 5297826 rpsQ Thermosipho melanesiensis BI429 30S ribosomal protein S17 YP_001306208.1 993166 D 391009 CDS YP_001306209.1 150020855 5297827 993455..993823 1 NC_009616.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 993823 rplN 5297827 rplN Thermosipho melanesiensis BI429 50S ribosomal protein L14 YP_001306209.1 993455 D 391009 CDS YP_001306210.1 150020856 5297317 993837..994157 1 NC_009616.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 994157 rplX 5297317 rplX Thermosipho melanesiensis BI429 50S ribosomal protein L24 YP_001306210.1 993837 D 391009 CDS YP_001306211.1 150020857 5297318 994171..994719 1 NC_009616.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 994719 rplE 5297318 rplE Thermosipho melanesiensis BI429 50S ribosomal protein L5 YP_001306211.1 994171 D 391009 CDS YP_001306212.1 150020858 5297821 994732..994917 1 NC_009616.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 994917 rpsN 5297821 rpsN Thermosipho melanesiensis BI429 30S ribosomal protein S14 YP_001306212.1 994732 D 391009 CDS YP_001306213.1 150020859 5297822 994933..995337 1 NC_009616.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 995337 rpsH 5297822 rpsH Thermosipho melanesiensis BI429 30S ribosomal protein S8 YP_001306213.1 994933 D 391009 CDS YP_001306214.1 150020860 5297148 995351..995905 1 NC_009616.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 995905 rplF 5297148 rplF Thermosipho melanesiensis BI429 50S ribosomal protein L6 YP_001306214.1 995351 D 391009 CDS YP_001306215.1 150020861 5297149 995921..996289 1 NC_009616.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 996289 rplR 5297149 rplR Thermosipho melanesiensis BI429 50S ribosomal protein L18 YP_001306215.1 995921 D 391009 CDS YP_001306216.1 150020862 5297321 996304..996834 1 NC_009616.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 996834 rpsE 5297321 rpsE Thermosipho melanesiensis BI429 30S ribosomal protein S5 YP_001306216.1 996304 D 391009 CDS YP_001306217.1 150020863 5297322 996836..997021 1 NC_009616.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 997021 rpmD 5297322 rpmD Thermosipho melanesiensis BI429 50S ribosomal protein L30 YP_001306217.1 996836 D 391009 CDS YP_001306218.1 150020864 5297062 997036..997479 1 NC_009616.1 late assembly protein; 50S ribosomal protein L15 997479 rplO 5297062 rplO Thermosipho melanesiensis BI429 50S ribosomal protein L15 YP_001306218.1 997036 D 391009 CDS YP_001306219.1 150020865 5297063 997482..998768 1 NC_009616.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 998768 secY 5297063 secY Thermosipho melanesiensis BI429 preprotein translocase subunit SecY YP_001306219.1 997482 D 391009 CDS YP_001306220.1 150020866 5297726 998773..999417 1 NC_009616.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 999417 adk 5297726 adk Thermosipho melanesiensis BI429 adenylate kinase YP_001306220.1 998773 D 391009 CDS YP_001306221.1 150020867 5297727 999423..1000175 1 NC_009616.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; methionine aminopeptidase, type I 1000175 5297727 Tmel_0975 Thermosipho melanesiensis BI429 methionine aminopeptidase, type I YP_001306221.1 999423 D 391009 CDS YP_001306222.1 150020868 5296877 1000181..1000405 1 NC_009616.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1000405 infA 5296877 infA Thermosipho melanesiensis BI429 translation initiation factor IF-1 YP_001306222.1 1000181 D 391009 CDS YP_001306223.1 150020869 5296878 1000424..1000540 1 NC_009616.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1000540 rpmJ 5296878 rpmJ Thermosipho melanesiensis BI429 50S ribosomal protein L36 YP_001306223.1 1000424 D 391009 CDS YP_001306224.1 150020870 5297055 1000553..1000921 1 NC_009616.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1000921 rpsM 5297055 rpsM Thermosipho melanesiensis BI429 30S ribosomal protein S13 YP_001306224.1 1000553 D 391009 CDS YP_001306225.1 150020871 5297056 1000934..1001323 1 NC_009616.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1001323 5297056 Tmel_0979 Thermosipho melanesiensis BI429 30S ribosomal protein S11 YP_001306225.1 1000934 D 391009 CDS YP_001306226.1 150020872 5296545 1001337..1001966 1 NC_009616.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1001966 rpsD 5296545 rpsD Thermosipho melanesiensis BI429 30S ribosomal protein S4 YP_001306226.1 1001337 D 391009 CDS YP_001306227.1 150020873 5296546 1001973..1002959 1 NC_009616.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1002959 5296546 Tmel_0981 Thermosipho melanesiensis BI429 DNA-directed RNA polymerase subunit alpha YP_001306227.1 1001973 D 391009 CDS YP_001306228.1 150020874 5296613 1002961..1003344 1 NC_009616.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1003344 rplQ 5296613 rplQ Thermosipho melanesiensis BI429 50S ribosomal protein L17 YP_001306228.1 1002961 D 391009 CDS YP_001306229.1 150020875 5296614 1003385..1004692 1 NC_009616.1 PFAM: trigger factor, C-terminal domain protein; trigger factor, N-terminal domain; trigger factor domain-containing protein 1004692 5296614 Tmel_0983 Thermosipho melanesiensis BI429 trigger factor domain-containing protein YP_001306229.1 1003385 D 391009 CDS YP_001306230.1 150020876 5297543 1004676..1005284 1 NC_009616.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1005284 clpP 5297543 clpP Thermosipho melanesiensis BI429 ATP-dependent Clp protease proteolytic subunit YP_001306230.1 1004676 D 391009 CDS YP_001306231.1 150020877 5297544 1005333..1006091 1 NC_009616.1 PFAM: protein of unknown function DUF28; hypothetical protein 1006091 5297544 Tmel_0985 Thermosipho melanesiensis BI429 hypothetical protein YP_001306231.1 1005333 D 391009 CDS YP_001306232.1 150020878 5297286 1006093..1006815 1 NC_009616.1 hypothetical protein 1006815 5297286 Tmel_0986 Thermosipho melanesiensis BI429 hypothetical protein YP_001306232.1 1006093 D 391009 CDS YP_001306233.1 150020879 5297287 1006796..1007608 1 NC_009616.1 PFAM: MCP methyltransferase, CheR-type; protein-glutamate O-methyltransferase 1007608 5297287 Tmel_0987 Thermosipho melanesiensis BI429 protein-glutamate O-methyltransferase YP_001306233.1 1006796 D 391009 CDS YP_001306234.1 150020880 5296882 1007618..1008163 1 NC_009616.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1008163 5296882 Tmel_0988 Thermosipho melanesiensis BI429 lipoprotein signal peptidase YP_001306234.1 1007618 D 391009 CDS YP_001306235.1 150020881 5296883 1008030..1008950 1 NC_009616.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RluA family pseudouridine synthase 1008950 5296883 Tmel_0989 Thermosipho melanesiensis BI429 RluA family pseudouridine synthase YP_001306235.1 1008030 D 391009 CDS YP_001306236.1 150020882 5296740 1009036..1010355 1 NC_009616.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; glutamine synthetase, type I 1010355 5296740 Tmel_0990 Thermosipho melanesiensis BI429 glutamine synthetase, type I YP_001306236.1 1009036 D 391009 CDS YP_001306237.1 150020883 5296741 complement(1010370..1011230) 1 NC_009616.1 TIGRFAM: cysteinyl-tRNA synthetase; PFAM: TM1410 hypothetical-related protein; cysteinyl-tRNA synthetase 1011230 5296741 Tmel_0991 Thermosipho melanesiensis BI429 cysteinyl-tRNA synthetase YP_001306237.1 1010370 R 391009 CDS YP_001306238.1 150020884 5296867 complement(1011227..1013497) 1 NC_009616.1 hypothetical protein 1013497 5296867 Tmel_0992 Thermosipho melanesiensis BI429 hypothetical protein YP_001306238.1 1011227 R 391009 CDS YP_001306239.1 150020885 5296868 complement(1013494..1014885) 1 NC_009616.1 hypothetical protein 1014885 5296868 Tmel_0993 Thermosipho melanesiensis BI429 hypothetical protein YP_001306239.1 1013494 R 391009 CDS YP_001306240.1 150020886 5297805 complement(1014887..1016302) 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1016302 5297805 Tmel_0994 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001306240.1 1014887 R 391009 CDS YP_001306241.1 150020887 5297806 complement(1016295..1016681) 1 NC_009616.1 hypothetical protein 1016681 5297806 Tmel_0995 Thermosipho melanesiensis BI429 hypothetical protein YP_001306241.1 1016295 R 391009 CDS YP_001306242.1 150020888 5296615 complement(1016686..1017543) 1 NC_009616.1 hypothetical protein 1017543 5296615 Tmel_0996 Thermosipho melanesiensis BI429 hypothetical protein YP_001306242.1 1016686 R 391009 CDS YP_001306243.1 150020889 5296616 complement(1017540..1018736) 1 NC_009616.1 hypothetical protein 1018736 5296616 Tmel_0997 Thermosipho melanesiensis BI429 hypothetical protein YP_001306243.1 1017540 R 391009 CDS YP_001306244.1 150020890 5296574 1019023..1020426 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1020426 5296574 Tmel_0998 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306244.1 1019023 D 391009 CDS YP_001306245.1 150020891 5296575 1020429..1020908 1 NC_009616.1 hypothetical protein 1020908 5296575 Tmel_0999 Thermosipho melanesiensis BI429 hypothetical protein YP_001306245.1 1020429 D 391009 CDS YP_001306246.1 150020892 5297018 1020905..1021618 1 NC_009616.1 PFAM: peptidase M22, glycoprotease; peptidase M22, glycoprotease 1021618 5297018 Tmel_1000 Thermosipho melanesiensis BI429 peptidase M22, glycoprotease YP_001306246.1 1020905 D 391009 CDS YP_001306247.1 150020893 5297019 1021611..1024070 1 NC_009616.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1024070 5297019 Tmel_1001 Thermosipho melanesiensis BI429 DNA mismatch repair protein MutS YP_001306247.1 1021611 D 391009 CDS YP_001306248.1 150020894 5296495 1024067..1025749 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1025749 5296495 Tmel_1002 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306248.1 1024067 D 391009 CDS YP_001306249.1 150020895 5296496 complement(1025743..1026261) 1 NC_009616.1 PFAM: AMMECR1 domain protein; AMMECR1 domain-containing protein 1026261 5296496 Tmel_1003 Thermosipho melanesiensis BI429 AMMECR1 domain-containing protein YP_001306249.1 1025743 R 391009 CDS YP_001306250.1 150020896 5296888 complement(1026258..1026770) 1 NC_009616.1 hypothetical protein 1026770 5296888 Tmel_1004 Thermosipho melanesiensis BI429 hypothetical protein YP_001306250.1 1026258 R 391009 CDS YP_001306251.1 150020897 5296889 complement(1026767..1027342) 1 NC_009616.1 hypothetical protein 1027342 5296889 Tmel_1005 Thermosipho melanesiensis BI429 hypothetical protein YP_001306251.1 1026767 R 391009 CDS YP_001306252.1 150020898 5297516 complement(1027348..1028211) 1 NC_009616.1 PFAM: phosphoadenosine phosphosulfate reductase; PP-loop domain protein; PP-loop domain-containing protein 1028211 5297516 Tmel_1006 Thermosipho melanesiensis BI429 PP-loop domain-containing protein YP_001306252.1 1027348 R 391009 CDS YP_001306253.1 150020899 5297517 complement(1028224..1029417) 1 NC_009616.1 PFAM: protein of unknown function DUF1063; hypothetical protein 1029417 5297517 Tmel_1007 Thermosipho melanesiensis BI429 hypothetical protein YP_001306253.1 1028224 R 391009 CDS YP_001306254.1 150020900 5297428 1029488..1031047 1 NC_009616.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; OB-fold, tRNA/helicase-type nucleic acid binding protein 1031047 5297428 Tmel_1008 Thermosipho melanesiensis BI429 OB-fold, tRNA/helicase-type nucleic acid binding protein YP_001306254.1 1029488 D 391009 CDS YP_001306255.1 150020901 5297429 complement(1031072..1032613) 1 NC_009616.1 PFAM: carbohydrate kinase, FGGY; carbohydrate kinase, FGGY 1032613 5297429 Tmel_1009 Thermosipho melanesiensis BI429 carbohydrate kinase, FGGY YP_001306255.1 1031072 R 391009 CDS YP_001306256.1 150020902 5296491 complement(1032680..1033792) 1 NC_009616.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 1033792 5296491 Tmel_1010 Thermosipho melanesiensis BI429 lysine 2,3-aminomutase YodO family protein YP_001306256.1 1032680 R 391009 CDS YP_001306257.1 150020903 5296492 complement(1034056..1037022) 1 NC_009616.1 PFAM: glycoside hydrolase, family 38; glycosyl hydrolase 38 domain protein; Glycoside hydrolase, family 38, central region; glycoside hydrolase family protein 1037022 5296492 Tmel_1011 Thermosipho melanesiensis BI429 glycoside hydrolase family protein YP_001306257.1 1034056 R 391009 CDS YP_001306258.1 150020904 5297796 complement(1037015..1038043) 1 NC_009616.1 PFAM: regulatory protein GntR, HTH; periplasmic binding protein/LacI transcriptional regulator; regulatory protein GntR 1038043 5297796 Tmel_1012 Thermosipho melanesiensis BI429 regulatory protein GntR YP_001306258.1 1037015 R 391009 CDS YP_001306259.1 150020905 5297797 complement(1038054..1038992) 1 NC_009616.1 PFAM: glycosidase, PH1107-related; glycosidase 1038992 5297797 Tmel_1013 Thermosipho melanesiensis BI429 glycosidase YP_001306259.1 1038054 R 391009 CDS YP_001306260.1 150020906 5297004 complement(1039006..1039827) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1039827 5297004 Tmel_1014 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306260.1 1039006 R 391009 CDS YP_001306261.1 150020907 5297005 complement(1039839..1040717) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1040717 5297005 Tmel_1015 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306261.1 1039839 R 391009 CDS YP_001306262.1 150020908 5296580 complement(1040769..1043411) 1 NC_009616.1 PFAM: coagulation factor 5/8 type domain protein; PKD domain containing protein; glycoside hydrolase, family 85; glycoside hydrolase family protein 1043411 5296580 Tmel_1016 Thermosipho melanesiensis BI429 glycoside hydrolase family protein YP_001306262.1 1040769 R 391009 CDS YP_001306263.1 150020909 5296581 complement(1043423..1044676) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 1044676 5296581 Tmel_1017 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306263.1 1043423 R 391009 CDS YP_001306264.1 150020910 5296712 1044942..1047527 1 NC_009616.1 PFAM: MMPL domain protein; MMPL domain-containing protein 1047527 5296712 Tmel_1018 Thermosipho melanesiensis BI429 MMPL domain-containing protein YP_001306264.1 1044942 D 391009 CDS YP_001306265.1 150020911 5296713 1047524..1048288 1 NC_009616.1 hypothetical protein 1048288 5296713 Tmel_1019 Thermosipho melanesiensis BI429 hypothetical protein YP_001306265.1 1047524 D 391009 CDS YP_001306266.1 150020912 5296840 1048305..1049507 1 NC_009616.1 hypothetical protein 1049507 5296840 Tmel_1020 Thermosipho melanesiensis BI429 hypothetical protein YP_001306266.1 1048305 D 391009 CDS YP_001306267.1 150020913 5296841 1049524..1050006 1 NC_009616.1 PFAM: PHA accumulation regulator DNA-binding protein; PHA accumulation regulator DNA-binding protein 1050006 5296841 Tmel_1021 Thermosipho melanesiensis BI429 PHA accumulation regulator DNA-binding protein YP_001306267.1 1049524 D 391009 CDS YP_001306268.1 150020914 5297875 1050008..1050763 1 NC_009616.1 PFAM: transferase hexapeptide repeat containing protein; hexapaptide repeat-containing transferase 1050763 5297875 Tmel_1022 Thermosipho melanesiensis BI429 hexapaptide repeat-containing transferase YP_001306268.1 1050008 D 391009 CDS YP_001306269.1 150020915 5297876 complement(1050748..1051248) 1 NC_009616.1 PFAM: Chromate transporter; chromate transporter 1051248 5297876 Tmel_1023 Thermosipho melanesiensis BI429 chromate transporter YP_001306269.1 1050748 R 391009 CDS YP_001306270.1 150020916 5296777 complement(1051259..1053349) 1 NC_009616.1 TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DNA topoisomerase I 1053349 5296777 Tmel_1024 Thermosipho melanesiensis BI429 DNA topoisomerase I YP_001306270.1 1051259 R 391009 CDS YP_001306271.1 150020917 5296778 complement(1053351..1054361) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1054361 5296778 Tmel_1025 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306271.1 1053351 R 391009 CDS YP_001306272.1 150020918 5296899 complement(1054358..1055452) 1 NC_009616.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase 1055452 5296899 Tmel_1026 Thermosipho melanesiensis BI429 alanine racemase YP_001306272.1 1054358 R 391009 CDS YP_001306273.1 150020919 5296900 complement(1055778..1055990) 1 NC_009616.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1055990 rpmB 5296900 rpmB Thermosipho melanesiensis BI429 50S ribosomal protein L28 YP_001306273.1 1055778 R 391009 CDS YP_001306274.1 150020920 5296796 complement(1056104..1058668) 1 NC_009616.1 PFAM: protein of unknown function DUF214; hypothetical protein 1058668 5296796 Tmel_1028 Thermosipho melanesiensis BI429 hypothetical protein YP_001306274.1 1056104 R 391009 CDS YP_001306275.1 150020921 5296797 complement(1058678..1059790) 1 NC_009616.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma-70; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; RpoD family RNA polymerase sigma factor 1059790 5296797 Tmel_1029 Thermosipho melanesiensis BI429 RpoD family RNA polymerase sigma factor YP_001306275.1 1058678 R 391009 CDS YP_001306276.1 150020922 5297038 complement(1059798..1061390) 1 NC_009616.1 TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein; DNA primase 1061390 5297038 Tmel_1030 Thermosipho melanesiensis BI429 DNA primase YP_001306276.1 1059798 R 391009 CDS YP_001306277.1 150020923 5297039 complement(1061448..1061846) 1 NC_009616.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1061846 rpsI 5297039 rpsI Thermosipho melanesiensis BI429 30S ribosomal protein S9 YP_001306277.1 1061448 R 391009 CDS YP_001306278.1 150020924 5297699 complement(1061862..1062353) 1 NC_009616.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1062353 rplM 5297699 rplM Thermosipho melanesiensis BI429 50S ribosomal protein L13 YP_001306278.1 1061862 R 391009 CDS YP_001306279.1 150020925 5297700 complement(1062328..1062861) 1 NC_009616.1 hypothetical protein 1062861 5297700 Tmel_1033 Thermosipho melanesiensis BI429 hypothetical protein YP_001306279.1 1062328 R 391009 CDS YP_001306280.1 150020926 5297021 complement(1062873..1063130) 1 NC_009616.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1063130 rpmA 5297021 rpmA Thermosipho melanesiensis BI429 50S ribosomal protein L27 YP_001306280.1 1062873 R 391009 CDS YP_001306281.1 150020927 5297022 complement(1063120..1063431) 1 NC_009616.1 PFAM: protein of unknown function DUF464; hypothetical protein 1063431 5297022 Tmel_1035 Thermosipho melanesiensis BI429 hypothetical protein YP_001306281.1 1063120 R 391009 CDS YP_001306282.1 150020928 5297110 complement(1063428..1063748) 1 NC_009616.1 PFAM: ribosomal protein L21; 50S ribosomal protein L21 1063748 rplU 5297110 rplU Thermosipho melanesiensis BI429 50S ribosomal protein L21 YP_001306282.1 1063428 R 391009 CDS YP_001306283.1 150020929 5297111 1063982..1065082 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 1065082 5297111 Tmel_1037 Thermosipho melanesiensis BI429 major facilitator transporter YP_001306283.1 1063982 D 391009 CDS YP_001306284.1 150020930 5297112 1065085..1065558 1 NC_009616.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1065558 ruvC 5297112 ruvC Thermosipho melanesiensis BI429 Holliday junction resolvase YP_001306284.1 1065085 D 391009 CDS YP_001306285.1 150020931 5297113 1065570..1069658 1 NC_009616.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1069658 polC 5297113 polC Thermosipho melanesiensis BI429 DNA polymerase III PolC YP_001306285.1 1065570 D 391009 CDS YP_001306286.1 150020932 5297253 1069834..1070109 1 NC_009616.1 PFAM: Stage V sporulation protein S; stage V sporulation protein S 1070109 5297253 Tmel_1040 Thermosipho melanesiensis BI429 stage V sporulation protein S YP_001306286.1 1069834 D 391009 CDS YP_001306287.1 150020933 5297254 1070117..1070350 1 NC_009616.1 hypothetical protein 1070350 5297254 Tmel_1041 Thermosipho melanesiensis BI429 hypothetical protein YP_001306287.1 1070117 D 391009 CDS YP_001306288.1 150020934 5296497 1070381..1071238 1 NC_009616.1 PFAM: protein of unknown function DUF1385; hypothetical protein 1071238 5296497 Tmel_1042 Thermosipho melanesiensis BI429 hypothetical protein YP_001306288.1 1070381 D 391009 CDS YP_001306289.1 150020935 5296498 complement(1071247..1072395) 1 NC_009616.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; diaminopimelate decarboxylase 1072395 5296498 Tmel_1043 Thermosipho melanesiensis BI429 diaminopimelate decarboxylase YP_001306289.1 1071247 R 391009 CDS YP_001306290.1 150020936 5296690 complement(1072392..1073486) 1 NC_009616.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; amidohydrolase 1073486 5296690 Tmel_1044 Thermosipho melanesiensis BI429 amidohydrolase YP_001306290.1 1072392 R 391009 CDS YP_001306291.1 150020937 5296691 1073582..1074556 1 NC_009616.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1074556 pheS 5296691 pheS Thermosipho melanesiensis BI429 phenylalanyl-tRNA synthetase subunit alpha YP_001306291.1 1073582 D 391009 CDS YP_001306292.1 150020938 5297737 1074558..1075472 1 NC_009616.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1075472 5297737 Tmel_1046 Thermosipho melanesiensis BI429 tRNA pseudouridine synthase B YP_001306292.1 1074558 D 391009 CDS YP_001306293.1 150020939 5297738 1075513..1076580 1 NC_009616.1 PFAM: TGS domain protein; Protein of unknown function DUF933; hypothetical protein 1076580 5297738 Tmel_1047 Thermosipho melanesiensis BI429 hypothetical protein YP_001306293.1 1075513 D 391009 CDS YP_001306294.1 150020940 5297614 1076592..1076828 1 NC_009616.1 hypothetical protein 1076828 5297614 Tmel_1048 Thermosipho melanesiensis BI429 hypothetical protein YP_001306294.1 1076592 D 391009 CDS YP_001306295.1 150020941 5297615 1076819..1078015 1 NC_009616.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1078015 5297615 Tmel_1049 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306295.1 1076819 D 391009 CDS YP_001306296.1 150020942 5297479 1077990..1078784 1 NC_009616.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 1078784 5297479 Tmel_1050 Thermosipho melanesiensis BI429 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001306296.1 1077990 D 391009 CDS YP_001306297.1 150020943 5297480 1078781..1079521 1 NC_009616.1 PFAM: zinc/iron permease; zinc/iron permease 1079521 5297480 Tmel_1051 Thermosipho melanesiensis BI429 zinc/iron permease YP_001306297.1 1078781 D 391009 CDS YP_001306298.1 150020944 5297809 1079533..1080612 1 NC_009616.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; oxidoreductase domain-containing protein 1080612 5297809 Tmel_1052 Thermosipho melanesiensis BI429 oxidoreductase domain-containing protein YP_001306298.1 1079533 D 391009 CDS YP_001306299.1 150020945 5297810 1080621..1081286 1 NC_009616.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase 1081286 5297810 Tmel_1053 Thermosipho melanesiensis BI429 HAD family hydrolase YP_001306299.1 1080621 D 391009 CDS YP_001306300.1 150020946 5297141 complement(1082086..1083171) 1 NC_009616.1 PFAM: 2-nitropropane dioxygenase, NPD; 2-nitropropane dioxygenase 1083171 5297141 Tmel_1055 Thermosipho melanesiensis BI429 2-nitropropane dioxygenase YP_001306300.1 1082086 R 391009 CDS YP_001306301.1 150020947 5297565 1083916..1085466 1 NC_009616.1 PFAM: protein of unknown function DUF1703; hypothetical protein 1085466 5297565 Tmel_1056 Thermosipho melanesiensis BI429 hypothetical protein YP_001306301.1 1083916 D 391009 CDS YP_001306302.1 150020948 5296563 complement(1085683..1086243) 1 NC_009616.1 hypothetical protein 1086243 5296563 Tmel_1057 Thermosipho melanesiensis BI429 hypothetical protein YP_001306302.1 1085683 R 391009 CDS YP_001306303.1 150020949 5296564 complement(1086255..1086977) 1 NC_009616.1 hypothetical protein 1086977 5296564 Tmel_1058 Thermosipho melanesiensis BI429 hypothetical protein YP_001306303.1 1086255 R 391009 CDS YP_001306304.1 150020950 5296665 complement(1087090..1087425) 1 NC_009616.1 ECF subfamily RNA polymerase sigma-24 factor 1087425 5296665 Tmel_1059 Thermosipho melanesiensis BI429 ECF subfamily RNA polymerase sigma-24 factor YP_001306304.1 1087090 R 391009 CDS YP_001306305.1 150020951 5296666 complement(1087469..1087657) 1 NC_009616.1 hypothetical protein 1087657 5296666 Tmel_1060 Thermosipho melanesiensis BI429 hypothetical protein YP_001306305.1 1087469 R 391009 CDS YP_001306306.1 150020952 5297743 complement(1087669..1087881) 1 NC_009616.1 hypothetical protein 1087881 5297743 Tmel_1061 Thermosipho melanesiensis BI429 hypothetical protein YP_001306306.1 1087669 R 391009 CDS YP_001306307.1 150020953 5297744 complement(1087907..1088092) 1 NC_009616.1 hypothetical protein 1088092 5297744 Tmel_1062 Thermosipho melanesiensis BI429 hypothetical protein YP_001306307.1 1087907 R 391009 CDS YP_001306308.1 150020954 5297639 1088824..1090122 1 NC_009616.1 PFAM: sugar transferase; sugar transferase 1090122 5297639 Tmel_1063 Thermosipho melanesiensis BI429 sugar transferase YP_001306308.1 1088824 D 391009 CDS YP_001306309.1 150020955 5297640 1090124..1091233 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1091233 5297640 Tmel_1064 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001306309.1 1090124 D 391009 CDS YP_001306310.1 150020956 5297759 1091247..1092410 1 NC_009616.1 hypothetical protein 1092410 5297759 Tmel_1065 Thermosipho melanesiensis BI429 hypothetical protein YP_001306310.1 1091247 D 391009 CDS YP_001306311.1 150020957 5297760 1092422..1093537 1 NC_009616.1 hypothetical protein 1093537 5297760 Tmel_1066 Thermosipho melanesiensis BI429 hypothetical protein YP_001306311.1 1092422 D 391009 CDS YP_001306312.1 150020958 5297197 1093621..1094796 1 NC_009616.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like; UDP-glucose 6-dehydrogenase 1094796 5297197 Tmel_1067 Thermosipho melanesiensis BI429 UDP-glucose 6-dehydrogenase YP_001306312.1 1093621 D 391009 CDS YP_001306313.1 150020959 5297198 1094812..1095726 1 NC_009616.1 PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 1095726 5297198 Tmel_1068 Thermosipho melanesiensis BI429 glycosyl transferase family protein YP_001306313.1 1094812 D 391009 CDS YP_001306314.1 150020960 5296762 1095750..1096640 1 NC_009616.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidylyltransferase 1096640 5296762 Tmel_1069 Thermosipho melanesiensis BI429 glucose-1-phosphate thymidylyltransferase YP_001306314.1 1095750 D 391009 CDS YP_001306315.1 150020961 5296763 1096657..1097229 1 NC_009616.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1097229 5296763 Tmel_1070 Thermosipho melanesiensis BI429 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001306315.1 1096657 D 391009 CDS YP_001306316.1 150020962 5297162 1097226..1098083 1 NC_009616.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 1098083 5297162 Tmel_1071 Thermosipho melanesiensis BI429 dTDP-4-dehydrorhamnose reductase YP_001306316.1 1097226 D 391009 CDS YP_001306317.1 150020963 5297163 1098096..1099154 1 NC_009616.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; dTDP-glucose 4,6-dehydratase 1099154 5297163 Tmel_1072 Thermosipho melanesiensis BI429 dTDP-glucose 4,6-dehydratase YP_001306317.1 1098096 D 391009 CDS YP_001306318.1 150020964 5297298 1099164..1100414 1 NC_009616.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase 1100414 5297298 Tmel_1073 Thermosipho melanesiensis BI429 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001306318.1 1099164 D 391009 CDS YP_001306319.1 150020965 5297299 1100419..1101849 1 NC_009616.1 PFAM: polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 1101849 5297299 Tmel_1074 Thermosipho melanesiensis BI429 polysaccharide biosynthesis protein YP_001306319.1 1100419 D 391009 CDS YP_001306320.1 150020966 5296804 1101849..1102352 1 NC_009616.1 TIGRFAM: cytidyltransferase-related domain; glycerol-3-phosphate cytidylyltransferase; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; glycerol-3-phosphate cytidylyltransferase 1102352 5296804 Tmel_1075 Thermosipho melanesiensis BI429 glycerol-3-phosphate cytidylyltransferase YP_001306320.1 1101849 D 391009 CDS YP_001306321.1 150020967 5296805 1102757..1103341 1 NC_009616.1 hypothetical protein 1103341 5296805 Tmel_1076 Thermosipho melanesiensis BI429 hypothetical protein YP_001306321.1 1102757 D 391009 CDS YP_001306322.1 150020968 5297325 1103771..1103962 1 NC_009616.1 hypothetical protein 1103962 5297325 Tmel_1077 Thermosipho melanesiensis BI429 hypothetical protein YP_001306322.1 1103771 D 391009 CDS YP_001306323.1 150020969 5297326 1104048..1104260 1 NC_009616.1 hypothetical protein 1104260 5297326 Tmel_1078 Thermosipho melanesiensis BI429 hypothetical protein YP_001306323.1 1104048 D 391009 CDS YP_001306324.1 150020970 5296920 1104274..1104462 1 NC_009616.1 hypothetical protein 1104462 5296920 Tmel_1079 Thermosipho melanesiensis BI429 hypothetical protein YP_001306324.1 1104274 D 391009 CDS YP_001306325.1 150020971 5296921 1104588..1104920 1 NC_009616.1 hypothetical protein 1104920 5296921 Tmel_1080 Thermosipho melanesiensis BI429 hypothetical protein YP_001306325.1 1104588 D 391009 CDS YP_001306326.1 150020972 5296981 1105139..1106104 1 NC_009616.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; UDP-glucose 4-epimerase 1106104 5296981 Tmel_1081 Thermosipho melanesiensis BI429 UDP-glucose 4-epimerase YP_001306326.1 1105139 D 391009 CDS YP_001306327.1 150020973 5296982 1106198..1106374 1 NC_009616.1 hypothetical protein 1106374 5296982 Tmel_1082 Thermosipho melanesiensis BI429 hypothetical protein YP_001306327.1 1106198 D 391009 CDS YP_001306328.1 150020974 5296654 1106437..1107381 1 NC_009616.1 PFAM: metallophosphoesterase; metallophosphoesterase 1107381 5296654 Tmel_1083 Thermosipho melanesiensis BI429 metallophosphoesterase YP_001306328.1 1106437 D 391009 CDS YP_001306329.1 150020975 5296655 1107417..1107617 1 NC_009616.1 hypothetical protein 1107617 5296655 Tmel_1084 Thermosipho melanesiensis BI429 hypothetical protein YP_001306329.1 1107417 D 391009 CDS YP_001306330.1 150020976 5296617 1107598..1109823 1 NC_009616.1 DNA repair ATPase-like protein 1109823 5296617 Tmel_1085 Thermosipho melanesiensis BI429 DNA repair ATPase-like protein YP_001306330.1 1107598 D 391009 CDS YP_001306331.1 150020977 5296618 1109921..1110223 1 NC_009616.1 hypothetical protein 1110223 5296618 Tmel_1086 Thermosipho melanesiensis BI429 hypothetical protein YP_001306331.1 1109921 D 391009 CDS YP_001306332.1 150020978 5296971 1110306..1112156 1 NC_009616.1 ATP-dependent OLD family endonuclease 1112156 5296971 Tmel_1087 Thermosipho melanesiensis BI429 ATP-dependent OLD family endonuclease YP_001306332.1 1110306 D 391009 CDS YP_001306333.1 150020979 5296972 1112303..1113343 1 NC_009616.1 PFAM: AAA-4 family protein; putative transcriptional regulator 1113343 5296972 Tmel_1088 Thermosipho melanesiensis BI429 putative transcriptional regulator YP_001306333.1 1112303 D 391009 CDS YP_001306334.1 150020980 5297157 1113613..1114953 1 NC_009616.1 hypothetical protein 1114953 5297157 Tmel_1089 Thermosipho melanesiensis BI429 hypothetical protein YP_001306334.1 1113613 D 391009 CDS YP_001306335.1 150020981 5297158 1115021..1118725 1 NC_009616.1 PFAM: KAP P-loop domain protein; KAP P-loop domain-containing protein 1118725 5297158 Tmel_1090 Thermosipho melanesiensis BI429 KAP P-loop domain-containing protein YP_001306335.1 1115021 D 391009 CDS YP_001306336.1 150020982 5297851 1119207..1119521 1 NC_009616.1 hypothetical protein 1119521 5297851 Tmel_1091 Thermosipho melanesiensis BI429 hypothetical protein YP_001306336.1 1119207 D 391009 CDS YP_001306337.1 150020983 5297852 1119791..1120021 1 NC_009616.1 hypothetical protein 1120021 5297852 Tmel_1092 Thermosipho melanesiensis BI429 hypothetical protein YP_001306337.1 1119791 D 391009 CDS YP_001306338.1 150020984 5296787 1121044..1122417 1 NC_009616.1 PFAM: DUF234 DEXX-box ATPase; ATPase; ATPase 1122417 5296787 Tmel_1093 Thermosipho melanesiensis BI429 ATPase YP_001306338.1 1121044 D 391009 CDS YP_001306339.1 150020985 5296788 1122856..1123107 1 NC_009616.1 hypothetical protein 1123107 5296788 Tmel_1094 Thermosipho melanesiensis BI429 hypothetical protein YP_001306339.1 1122856 D 391009 CDS YP_001306340.1 150020986 5297710 complement(1123216..1123860) 1 NC_009616.1 hypothetical protein 1123860 5297710 Tmel_1095 Thermosipho melanesiensis BI429 hypothetical protein YP_001306340.1 1123216 R 391009 CDS YP_001306341.1 150020987 5298268 complement(1124974..1125141) 1 NC_009616.1 hypothetical protein 1125141 5298268 Tmel_1097 Thermosipho melanesiensis BI429 hypothetical protein YP_001306341.1 1124974 R 391009 CDS YP_001306342.1 150020988 5296728 1125191..1126018 1 NC_009616.1 arylsulfatase regulator (Fe-S oxidoreductase)-like protein 1126018 5296728 Tmel_1098 Thermosipho melanesiensis BI429 arylsulfatase regulator (Fe-S oxidoreductase)-like protein YP_001306342.1 1125191 D 391009 CDS YP_001306343.1 150020989 5296729 1126113..1127399 1 NC_009616.1 PFAM: peptidase S41; peptidase S41 1127399 5296729 Tmel_1099 Thermosipho melanesiensis BI429 peptidase S41 YP_001306343.1 1126113 D 391009 CDS YP_001306344.1 150020990 5297883 1127420..1127632 1 NC_009616.1 hypothetical protein 1127632 5297883 Tmel_1100 Thermosipho melanesiensis BI429 hypothetical protein YP_001306344.1 1127420 D 391009 CDS YP_001306345.1 150020991 5298205 1129513..1130130 1 NC_009616.1 PFAM: Domain of unknown function DUF1814; hypothetical protein 1130130 5298205 Tmel_1103 Thermosipho melanesiensis BI429 hypothetical protein YP_001306345.1 1129513 D 391009 CDS YP_001306346.1 150020992 5298206 complement(1131072..1132448) 1 NC_009616.1 SMART: AAA ATPase; AAA ATPase 1132448 5298206 Tmel_1105 Thermosipho melanesiensis BI429 AAA ATPase YP_001306346.1 1131072 R 391009 CDS YP_001306347.1 150020993 5296952 1132884..1133210 1 NC_009616.1 hypothetical protein 1133210 5296952 Tmel_1106 Thermosipho melanesiensis BI429 hypothetical protein YP_001306347.1 1132884 D 391009 CDS YP_001306348.1 150020994 5298115 1133488..1136049 1 NC_009616.1 hypothetical protein 1136049 5298115 Tmel_1108 Thermosipho melanesiensis BI429 hypothetical protein YP_001306348.1 1133488 D 391009 CDS YP_001306349.1 150020995 5296647 1136283..1137179 1 NC_009616.1 PFAM: protein of unknown function DUF1130; hypothetical protein 1137179 5296647 Tmel_1109 Thermosipho melanesiensis BI429 hypothetical protein YP_001306349.1 1136283 D 391009 CDS YP_001306350.1 150020996 5296949 1137176..1138012 1 NC_009616.1 hypothetical protein 1138012 5296949 Tmel_1110 Thermosipho melanesiensis BI429 hypothetical protein YP_001306350.1 1137176 D 391009 CDS YP_001306351.1 150020997 5296950 1138473..1139387 1 NC_009616.1 hypothetical protein 1139387 5296950 Tmel_1111 Thermosipho melanesiensis BI429 hypothetical protein YP_001306351.1 1138473 D 391009 CDS YP_001306352.1 150020998 5297341 1139381..1140121 1 NC_009616.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; type 11 methyltransferase 1140121 5297341 Tmel_1112 Thermosipho melanesiensis BI429 type 11 methyltransferase YP_001306352.1 1139381 D 391009 CDS YP_001306353.1 150020999 5297342 1140137..1140994 1 NC_009616.1 PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1140994 5297342 Tmel_1113 Thermosipho melanesiensis BI429 hypothetical protein YP_001306353.1 1140137 D 391009 CDS YP_001306354.1 150021000 5297133 1141987..1142904 1 NC_009616.1 hypothetical protein 1142904 5297133 Tmel_1114 Thermosipho melanesiensis BI429 hypothetical protein YP_001306354.1 1141987 D 391009 CDS YP_001306355.1 150021001 5297134 1143023..1143175 1 NC_009616.1 hypothetical protein 1143175 5297134 Tmel_1115 Thermosipho melanesiensis BI429 hypothetical protein YP_001306355.1 1143023 D 391009 CDS YP_001306356.1 150021002 5297447 1143193..1143510 1 NC_009616.1 hypothetical protein 1143510 5297447 Tmel_1116 Thermosipho melanesiensis BI429 hypothetical protein YP_001306356.1 1143193 D 391009 CDS YP_001306357.1 150021003 5297448 1143973..1144137 1 NC_009616.1 hypothetical protein 1144137 5297448 Tmel_1117 Thermosipho melanesiensis BI429 hypothetical protein YP_001306357.1 1143973 D 391009 CDS YP_001306358.1 150021004 5296842 complement(1144401..1144946) 1 NC_009616.1 hypothetical protein 1144946 5296842 Tmel_1118 Thermosipho melanesiensis BI429 hypothetical protein YP_001306358.1 1144401 R 391009 CDS YP_001306359.1 150021005 5296843 1145082..1145348 1 NC_009616.1 hypothetical protein 1145348 5296843 Tmel_1119 Thermosipho melanesiensis BI429 hypothetical protein YP_001306359.1 1145082 D 391009 CDS YP_001306360.1 150021006 5297200 complement(1146026..1148020) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1148020 5297200 Tmel_1120 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001306360.1 1146026 R 391009 CDS YP_001306361.1 150021007 5297201 1148311..1149042 1 NC_009616.1 PFAM: metallophosphoesterase; metallophosphoesterase 1149042 5297201 Tmel_1121 Thermosipho melanesiensis BI429 metallophosphoesterase YP_001306361.1 1148311 D 391009 CDS YP_001306362.1 150021008 5297551 complement(1149039..1149635) 1 NC_009616.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1149635 minC 5297551 minC Thermosipho melanesiensis BI429 septum formation inhibitor YP_001306362.1 1149039 R 391009 CDS YP_001306363.1 150021009 5297552 1149744..1150577 1 NC_009616.1 PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1150577 5297552 Tmel_1123 Thermosipho melanesiensis BI429 hypothetical protein YP_001306363.1 1149744 D 391009 CDS YP_001306364.1 150021010 5297605 1150604..1150987 1 NC_009616.1 TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; flagellar basal-body rod protein FlgB 1150987 5297605 Tmel_1124 Thermosipho melanesiensis BI429 flagellar basal-body rod protein FlgB YP_001306364.1 1150604 D 391009 CDS YP_001306365.1 150021011 5297606 1150999..1151412 1 NC_009616.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal-body rod protein FlgC 1151412 5297606 Tmel_1125 Thermosipho melanesiensis BI429 flagellar basal-body rod protein FlgC YP_001306365.1 1150999 D 391009 CDS YP_001306366.1 150021012 5297170 1151418..1151705 1 NC_009616.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex subunit FliE 1151705 5297170 Tmel_1126 Thermosipho melanesiensis BI429 flagellar hook-basal body complex subunit FliE YP_001306366.1 1151418 D 391009 CDS YP_001306367.1 150021013 5297171 complement(1151803..1152231) 1 NC_009616.1 PFAM: heat shock protein Hsp20; heat shock protein Hsp20 1152231 5297171 Tmel_1127 Thermosipho melanesiensis BI429 heat shock protein Hsp20 YP_001306367.1 1151803 R 391009 CDS YP_001306368.1 150021014 5297048 complement(1152254..1154044) 1 NC_009616.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1154044 dnaK 5297048 dnaK Thermosipho melanesiensis BI429 molecular chaperone DnaK YP_001306368.1 1152254 R 391009 CDS YP_001306369.1 150021015 5297049 complement(1154198..1154524) 1 NC_009616.1 PFAM: protein of unknown function DUF74; hypothetical protein 1154524 5297049 Tmel_1129 Thermosipho melanesiensis BI429 hypothetical protein YP_001306369.1 1154198 R 391009 CDS YP_001306370.1 150021016 5297535 complement(1154538..1155740) 1 NC_009616.1 hypothetical protein 1155740 5297535 Tmel_1130 Thermosipho melanesiensis BI429 hypothetical protein YP_001306370.1 1154538 R 391009 CDS YP_001306371.1 150021017 5297536 complement(1155743..1156486) 1 NC_009616.1 hypothetical protein 1156486 5297536 Tmel_1131 Thermosipho melanesiensis BI429 hypothetical protein YP_001306371.1 1155743 R 391009 CDS YP_001306372.1 150021018 5297410 complement(1156483..1157259) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1157259 5297410 Tmel_1132 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306372.1 1156483 R 391009 CDS YP_001306373.1 150021019 5297411 complement(1157246..1157614) 1 NC_009616.1 PFAM: regulatory protein GntR, HTH; regulatory protein GntR 1157614 5297411 Tmel_1133 Thermosipho melanesiensis BI429 regulatory protein GntR YP_001306373.1 1157246 R 391009 CDS YP_001306374.1 150021020 5297677 complement(1157731..1158927) 1 NC_009616.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase 1158927 5297677 Tmel_1134 Thermosipho melanesiensis BI429 acetyl-CoA acetyltransferase YP_001306374.1 1157731 R 391009 CDS YP_001306375.1 150021021 5298464 complement(1158947..1159591) 1 NC_009616.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit B 1159591 5298464 Tmel_1135 Thermosipho melanesiensis BI429 3-oxoacid CoA-transferase subunit B YP_001306375.1 1158947 R 391009 CDS YP_001306376.1 150021022 5298465 complement(1159588..1160241) 1 NC_009616.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit A 1160241 5298465 Tmel_1136 Thermosipho melanesiensis BI429 3-oxoacid CoA-transferase subunit A YP_001306376.1 1159588 R 391009 CDS YP_001306377.1 150021023 5298468 complement(1160409..1161719) 1 NC_009616.1 PFAM: Alkaline phosphatase; alkaline phosphatase 1161719 5298468 Tmel_1137 Thermosipho melanesiensis BI429 alkaline phosphatase YP_001306377.1 1160409 R 391009 CDS YP_001306378.1 150021024 5298469 complement(1161915..1163291) 1 NC_009616.1 TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutamate synthase (NADPH), homotetrameric 1163291 5298469 Tmel_1138 Thermosipho melanesiensis BI429 glutamate synthase (NADPH), homotetrameric YP_001306378.1 1161915 R 391009 CDS YP_001306379.1 150021025 5296829 complement(1163282..1164118) 1 NC_009616.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; ferredoxin-NADP(+) reductase subunit alpha 1164118 5296829 Tmel_1139 Thermosipho melanesiensis BI429 ferredoxin-NADP(+) reductase subunit alpha YP_001306379.1 1163282 R 391009 CDS YP_001306380.1 150021026 5296830 complement(1164132..1164956) 1 NC_009616.1 PFAM: PfkB domain protein; ribokinase-like domain-containing protein 1164956 5296830 Tmel_1140 Thermosipho melanesiensis BI429 ribokinase-like domain-containing protein YP_001306380.1 1164132 R 391009 CDS YP_001306381.1 150021027 5297424 complement(1164934..1165860) 1 NC_009616.1 PFAM: ROK family protein; ROK family protein 1165860 5297424 Tmel_1141 Thermosipho melanesiensis BI429 ROK family protein YP_001306381.1 1164934 R 391009 CDS YP_001306382.1 150021028 5297425 complement(1165857..1166618) 1 NC_009616.1 biotin synthetase-like protein 1166618 5297425 Tmel_1142 Thermosipho melanesiensis BI429 biotin synthetase-like protein YP_001306382.1 1165857 R 391009 CDS YP_001306383.1 150021029 5297512 complement(1166612..1167475) 1 NC_009616.1 PFAM: Radical SAM domain protein; radical SAM domain-containing protein 1167475 5297512 Tmel_1143 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306383.1 1166612 R 391009 CDS YP_001306384.1 150021030 5297513 complement(1167472..1168734) 1 NC_009616.1 PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1168734 5297513 Tmel_1144 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001306384.1 1167472 R 391009 CDS YP_001306385.1 150021031 5297108 complement(1168747..1170000) 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 1170000 5297108 Tmel_1145 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001306385.1 1168747 R 391009 CDS YP_001306386.1 150021032 5297109 complement(1170006..1170551) 1 NC_009616.1 hypothetical protein 1170551 5297109 Tmel_1146 Thermosipho melanesiensis BI429 hypothetical protein YP_001306386.1 1170006 R 391009 CDS YP_001306387.1 150021033 5297101 complement(1170544..1171110) 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 1171110 5297101 Tmel_1147 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001306387.1 1170544 R 391009 CDS YP_001306388.1 150021034 5296683 complement(1171169..1172302) 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; Hpt domain protein; CheA signal transduction histidine kinase 1172302 5296683 Tmel_1148 Thermosipho melanesiensis BI429 CheA signal transduction histidine kinase YP_001306388.1 1171169 R 391009 CDS YP_001306389.1 150021035 5296684 complement(1172307..1172990) 1 NC_009616.1 hypothetical protein 1172990 5296684 Tmel_1149 Thermosipho melanesiensis BI429 hypothetical protein YP_001306389.1 1172307 R 391009 CDS YP_001306390.1 150021036 5296858 complement(1172995..1173993) 1 NC_009616.1 PFAM: MCP methyltransferase, CheR-type; MCP methyltransferase, CheR-type 1173993 5296858 Tmel_1150 Thermosipho melanesiensis BI429 MCP methyltransferase, CheR-type YP_001306390.1 1172995 R 391009 CDS YP_001306391.1 150021037 5296859 1174059..1175009 1 NC_009616.1 PFAM: DNA polymerase III, delta; DNA polymerase III subunit delta 1175009 5296859 Tmel_1151 Thermosipho melanesiensis BI429 DNA polymerase III subunit delta YP_001306391.1 1174059 D 391009 CDS YP_001306392.1 150021038 5297310 1174993..1177071 1 NC_009616.1 RND efflux transporter 1177071 5297310 Tmel_1152 Thermosipho melanesiensis BI429 RND efflux transporter YP_001306392.1 1174993 D 391009 CDS YP_001306393.1 150021039 5297311 1177079..1177606 1 NC_009616.1 hypothetical protein 1177606 5297311 Tmel_1153 Thermosipho melanesiensis BI429 hypothetical protein YP_001306393.1 1177079 D 391009 CDS YP_001306394.1 150021040 5297601 1177618..1178133 1 NC_009616.1 hypothetical protein 1178133 5297601 Tmel_1154 Thermosipho melanesiensis BI429 hypothetical protein YP_001306394.1 1177618 D 391009 CDS YP_001306395.1 150021041 5297602 1178138..1179421 1 NC_009616.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein YliG 1179421 5297602 Tmel_1155 Thermosipho melanesiensis BI429 MiaB-like tRNA modifying protein YliG YP_001306395.1 1178138 D 391009 CDS YP_001306396.1 150021042 5297184 1179428..1179949 1 NC_009616.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1179949 5297184 Tmel_1156 Thermosipho melanesiensis BI429 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001306396.1 1179428 D 391009 CDS YP_001306397.1 150021043 5297185 1179956..1180525 1 NC_009616.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase, HXTX; 2'-5' RNA ligase 1180525 5297185 Tmel_1157 Thermosipho melanesiensis BI429 2'-5' RNA ligase YP_001306397.1 1179956 D 391009 CDS YP_001306398.1 150021044 5297637 1180518..1181567 1 NC_009616.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1181567 recA 5297637 recA Thermosipho melanesiensis BI429 recombinase A YP_001306398.1 1180518 D 391009 CDS YP_001306399.1 150021045 5297638 1181545..1181934 1 NC_009616.1 PFAM: regulatory protein RecX; regulatory protein RecX 1181934 5297638 Tmel_1159 Thermosipho melanesiensis BI429 regulatory protein RecX YP_001306399.1 1181545 D 391009 CDS YP_001306400.1 150021046 5297020 1181936..1183468 1 NC_009616.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1183468 5297020 Tmel_1160 Thermosipho melanesiensis BI429 phosphodiesterase YP_001306400.1 1181936 D 391009 CDS YP_001306401.1 150021047 5296588 complement(1183499..1184602) 1 NC_009616.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein 1184602 5296588 Tmel_1161 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306401.1 1183499 R 391009 CDS YP_001306402.1 150021048 5296589 complement(1184614..1184868) 1 NC_009616.1 TIGRFAM: prevent-host-death family protein; prevent-host-death family protein 1184868 5296589 Tmel_1162 Thermosipho melanesiensis BI429 prevent-host-death family protein YP_001306402.1 1184614 R 391009 CDS YP_001306403.1 150021049 5297125 1185013..1186461 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1186461 5297125 Tmel_1163 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306403.1 1185013 D 391009 CDS YP_001306404.1 150021050 5297126 1186502..1187056 1 NC_009616.1 PFAM: regulatory protein, TetR; TetR family transcriptional regulator 1187056 5297126 Tmel_1164 Thermosipho melanesiensis BI429 TetR family transcriptional regulator YP_001306404.1 1186502 D 391009 CDS YP_001306405.1 150021051 5297073 1187130..1187339 1 NC_009616.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1187339 rpmE 5297073 rpmE Thermosipho melanesiensis BI429 50S ribosomal protein L31 YP_001306405.1 1187130 D 391009 CDS YP_001306406.1 150021052 5297074 1187403..1187774 1 NC_009616.1 PFAM: RNA binding S1 domain protein; RNA-binding S1 domain-containing protein 1187774 5297074 Tmel_1166 Thermosipho melanesiensis BI429 RNA-binding S1 domain-containing protein YP_001306406.1 1187403 D 391009 CDS YP_001306407.1 150021053 5298116 complement(1188081..1189697) 1 NC_009616.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) 1189697 5298116 Tmel_1168 Thermosipho melanesiensis BI429 NADH dehydrogenase (quinone) YP_001306407.1 1188081 R 391009 CDS YP_001306408.1 150021054 5297698 complement(1189694..1190176) 1 NC_009616.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit 1190176 5297698 Tmel_1169 Thermosipho melanesiensis BI429 NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001306408.1 1189694 R 391009 CDS YP_001306409.1 150021055 5297302 complement(1190199..1192007) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) 1192007 5297302 Tmel_1170 Thermosipho melanesiensis BI429 NADH dehydrogenase (quinone) YP_001306409.1 1190199 R 391009 CDS YP_001306410.1 150021056 5297303 complement(1192023..1192400) 1 NC_009616.1 ferredoxin-like protein 1192400 5297303 Tmel_1171 Thermosipho melanesiensis BI429 ferredoxin-like protein YP_001306410.1 1192023 R 391009 CDS YP_001306411.1 150021057 5296992 complement(1192400..1192891) 1 NC_009616.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit 1192891 5296992 Tmel_1172 Thermosipho melanesiensis BI429 NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001306411.1 1192400 R 391009 CDS YP_001306412.1 150021058 5296993 complement(1193046..1193951) 1 NC_009616.1 TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase-like; glutamate formiminotransferase 1193951 5296993 Tmel_1173 Thermosipho melanesiensis BI429 glutamate formiminotransferase YP_001306412.1 1193046 R 391009 CDS YP_001306413.1 150021059 5297257 complement(1193948..1194712) 1 NC_009616.1 PFAM: inositol monophosphatase; inositol-phosphate phosphatase 1194712 5297257 Tmel_1174 Thermosipho melanesiensis BI429 inositol-phosphate phosphatase YP_001306413.1 1193948 R 391009 CDS YP_001306414.1 150021060 5297549 complement(1194705..1196306) 1 NC_009616.1 PFAM: penicillin-binding protein, transpeptidase; peptidoglycan glycosyltransferase 1196306 5297549 Tmel_1175 Thermosipho melanesiensis BI429 peptidoglycan glycosyltransferase YP_001306414.1 1194705 R 391009 CDS YP_001306415.1 150021061 5297550 complement(1196296..1197684) 1 NC_009616.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1197684 gltX 5297550 gltX Thermosipho melanesiensis BI429 glutamyl-tRNA synthetase YP_001306415.1 1196296 R 391009 CDS YP_001306416.1 150021062 5296940 complement(1197690..1198193) 1 NC_009616.1 hypothetical protein 1198193 5296940 Tmel_1177 Thermosipho melanesiensis BI429 hypothetical protein YP_001306416.1 1197690 R 391009 CDS YP_001306417.1 150021063 5296941 complement(1198190..1198840) 1 NC_009616.1 PFAM: initiation factor 2B related; initiation factor 2B-like protein 1198840 5296941 Tmel_1178 Thermosipho melanesiensis BI429 initiation factor 2B-like protein YP_001306417.1 1198190 R 391009 CDS YP_001306418.1 150021064 5297616 complement(1198833..1199777) 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1199777 5297616 Tmel_1179 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306418.1 1198833 R 391009 CDS YP_001306419.1 150021065 5297617 complement(1199774..1200205) 1 NC_009616.1 PFAM: GatB/Yqey domain protein; GatB/Yqey domain-containing protein 1200205 5297617 Tmel_1180 Thermosipho melanesiensis BI429 GatB/Yqey domain-containing protein YP_001306419.1 1199774 R 391009 CDS YP_001306420.1 150021066 5297724 complement(1200210..1201157) 1 NC_009616.1 PFAM: histone deacetylase superfamily; histone deacetylase superfamily protein 1201157 5297724 Tmel_1181 Thermosipho melanesiensis BI429 histone deacetylase superfamily protein YP_001306420.1 1200210 R 391009 CDS YP_001306421.1 150021067 5297725 complement(1201159..1201596) 1 NC_009616.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; RpiB/LacA/LacB family sugar-phosphate isomerase 1201596 5297725 Tmel_1182 Thermosipho melanesiensis BI429 RpiB/LacA/LacB family sugar-phosphate isomerase YP_001306421.1 1201159 R 391009 CDS YP_001306422.1 150021068 5297772 complement(1201610..1201948) 1 NC_009616.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist 1201948 5297772 Tmel_1183 Thermosipho melanesiensis BI429 anti-sigma-factor antagonist YP_001306422.1 1201610 R 391009 CDS YP_001306423.1 150021069 5297773 complement(1201960..1202559) 1 NC_009616.1 TIGRFAM: LexA repressor; PFAM: peptidase S24, S26A and S26B; LexA DNA-binding domain protein; SOS-response transcriptional repressor, LexA 1202559 5297773 Tmel_1184 Thermosipho melanesiensis BI429 SOS-response transcriptional repressor, LexA YP_001306423.1 1201960 R 391009 CDS YP_001306424.1 150021070 5297585 complement(1202556..1202924) 1 NC_009616.1 hypothetical protein 1202924 5297585 Tmel_1185 Thermosipho melanesiensis BI429 hypothetical protein YP_001306424.1 1202556 R 391009 CDS YP_001306425.1 150021071 5297586 complement(1202917..1205337) 1 NC_009616.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; DNA gyrase subunit A 1205337 5297586 Tmel_1186 Thermosipho melanesiensis BI429 DNA gyrase subunit A YP_001306425.1 1202917 R 391009 CDS YP_001306426.1 150021072 5296561 complement(1205352..1207256) 1 NC_009616.1 TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: t-RNA-binding domain protein; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase, class Ia-like; methionyl-tRNA synthetase 1207256 5296561 Tmel_1187 Thermosipho melanesiensis BI429 methionyl-tRNA synthetase YP_001306426.1 1205352 R 391009 CDS YP_001306427.1 150021073 5297776 1207476..1208975 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 1208975 5297776 Tmel_1188 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306427.1 1207476 D 391009 CDS YP_001306428.1 150021074 5297777 1209022..1210029 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1210029 5297777 Tmel_1189 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306428.1 1209022 D 391009 CDS YP_001306429.1 150021075 5297835 1210041..1210913 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1210913 5297835 Tmel_1190 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306429.1 1210041 D 391009 CDS YP_001306430.1 150021076 5297836 1210918..1211880 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1211880 5297836 Tmel_1191 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306430.1 1210918 D 391009 CDS YP_001306431.1 150021077 5296534 1211877..1212851 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1212851 5296534 Tmel_1192 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306431.1 1211877 D 391009 CDS YP_001306432.1 150021078 5296535 complement(1212868..1214436) 1 NC_009616.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit 1214436 pyrB 5296535 pyrB Thermosipho melanesiensis BI429 bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit YP_001306432.1 1212868 R 391009 CDS YP_001306433.1 150021079 5297477 complement(1214487..1215506) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1215506 5297477 Tmel_1194 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306433.1 1214487 R 391009 CDS YP_001306434.1 150021080 5297478 1215759..1216169 1 NC_009616.1 PFAM: ferric-uptake regulator; ferric uptake regulator family protein 1216169 5297478 Tmel_1195 Thermosipho melanesiensis BI429 ferric uptake regulator family protein YP_001306434.1 1215759 D 391009 CDS YP_001306435.1 150021081 5297695 1216171..1216809 1 NC_009616.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; peroxiredoxin 1216809 5297695 Tmel_1196 Thermosipho melanesiensis BI429 peroxiredoxin YP_001306435.1 1216171 D 391009 CDS YP_001306436.1 150021082 5297696 1216843..1217001 1 NC_009616.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; rubredoxin-type Fe(Cys)4 protein 1217001 5297696 Tmel_1197 Thermosipho melanesiensis BI429 rubredoxin-type Fe(Cys)4 protein YP_001306436.1 1216843 D 391009 CDS YP_001306437.1 150021083 5296603 1217003..1218157 1 NC_009616.1 PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; beta-lactamase domain-containing protein 1218157 5296603 Tmel_1198 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001306437.1 1217003 D 391009 CDS YP_001306438.1 150021084 5296604 1218173..1218682 1 NC_009616.1 PFAM: Ferritin, Dps family protein; ferroxidase 1218682 5296604 Tmel_1199 Thermosipho melanesiensis BI429 ferroxidase YP_001306438.1 1218173 D 391009 CDS YP_001306439.1 150021085 5296839 1218682..1218867 1 NC_009616.1 PFAM: Helix-turn-helix, type 11 domain protein; helix-turn-helix, type 11 domain-containing protein 1218867 5296839 Tmel_1200 Thermosipho melanesiensis BI429 helix-turn-helix, type 11 domain-containing protein YP_001306439.1 1218682 D 391009 CDS YP_001306440.1 150021086 5297644 1218870..1219250 1 NC_009616.1 TIGRFAM: desulfoferrodoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; desulfoferrodoxin 1219250 5297644 Tmel_1201 Thermosipho melanesiensis BI429 desulfoferrodoxin YP_001306440.1 1218870 D 391009 CDS YP_001306441.1 150021087 5297645 1219504..1219749 1 NC_009616.1 hypothetical protein 1219749 5297645 Tmel_1202 Thermosipho melanesiensis BI429 hypothetical protein YP_001306441.1 1219504 D 391009 CDS YP_001306442.1 150021088 5297599 1219751..1220020 1 NC_009616.1 hypothetical protein 1220020 5297599 Tmel_1203 Thermosipho melanesiensis BI429 hypothetical protein YP_001306442.1 1219751 D 391009 CDS YP_001306443.1 150021089 5297600 complement(1220038..1221699) 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1221699 5297600 Tmel_1204 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306443.1 1220038 R 391009 CDS YP_001306444.1 150021090 5296910 1221809..1222171 1 NC_009616.1 PFAM: transcriptional regulator PadR family protein; PadR-like family transcriptional regulator 1222171 5296910 Tmel_1205 Thermosipho melanesiensis BI429 PadR-like family transcriptional regulator YP_001306444.1 1221809 D 391009 CDS YP_001306445.1 150021091 5296911 1222171..1222734 1 NC_009616.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1222734 5296911 Tmel_1206 Thermosipho melanesiensis BI429 thymidine kinase YP_001306445.1 1222171 D 391009 CDS YP_001306446.1 150021092 5296582 1222731..1224521 1 NC_009616.1 PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; 5'-nucleotidase domain-containing protein 1224521 5296582 Tmel_1207 Thermosipho melanesiensis BI429 5'-nucleotidase domain-containing protein YP_001306446.1 1222731 D 391009 CDS YP_001306447.1 150021093 5296583 complement(1225036..1225677) 1 NC_009616.1 PFAM: protein of unknown function DUF1121; hypothetical protein 1225677 5296583 Tmel_1208 Thermosipho melanesiensis BI429 hypothetical protein YP_001306447.1 1225036 R 391009 CDS YP_001306448.1 150021094 5297524 complement(1225689..1226318) 1 NC_009616.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1226318 5297524 Tmel_1209 Thermosipho melanesiensis BI429 redox-sensing transcriptional repressor Rex YP_001306448.1 1225689 R 391009 CDS YP_001306449.1 150021095 5297525 1226611..1227093 1 NC_009616.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 1227093 5297525 Tmel_1210 Thermosipho melanesiensis BI429 putative monovalent cation/H+ antiporter subunit E YP_001306449.1 1226611 D 391009 CDS YP_001306450.1 150021096 5296960 1227090..1227347 1 NC_009616.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 1227347 5296960 Tmel_1211 Thermosipho melanesiensis BI429 putative monovalent cation/H+ antiporter subunit F YP_001306450.1 1227090 D 391009 CDS YP_001306451.1 150021097 5296961 1227344..1227664 1 NC_009616.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 1227664 5296961 Tmel_1212 Thermosipho melanesiensis BI429 putative monovalent cation/H+ antiporter subunit G YP_001306451.1 1227344 D 391009 CDS YP_001306452.1 150021098 5297459 1227661..1227900 1 NC_009616.1 hypothetical protein 1227900 5297459 Tmel_1213 Thermosipho melanesiensis BI429 hypothetical protein YP_001306452.1 1227661 D 391009 CDS YP_001306453.1 150021099 5297250 1227897..1228616 1 NC_009616.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 1228616 5297250 Tmel_1214 Thermosipho melanesiensis BI429 putative monovalent cation/H+ antiporter subunit B YP_001306453.1 1227897 D 391009 CDS YP_001306454.1 150021100 5297251 1228616..1228960 1 NC_009616.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L; NADH-ubiquinone oxidoreductase subunit 4L 1228960 5297251 Tmel_1215 Thermosipho melanesiensis BI429 NADH-ubiquinone oxidoreductase subunit 4L YP_001306454.1 1228616 D 391009 CDS YP_001306455.1 150021101 5297518 1228957..1230309 1 NC_009616.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH/ubiquinone/plastoquinone (complex I) 1230309 5297518 Tmel_1216 Thermosipho melanesiensis BI429 NADH/ubiquinone/plastoquinone (complex I) YP_001306455.1 1228957 D 391009 CDS YP_001306456.1 150021102 5297519 1230310..1232154 1 NC_009616.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH dehydrogenase subunit M 1232154 5297519 Tmel_1217 Thermosipho melanesiensis BI429 NADH dehydrogenase subunit M YP_001306456.1 1230310 D 391009 CDS YP_001306457.1 150021103 5297422 1232157..1233038 1 NC_009616.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1; respiratory-chain NADH dehydrogenase subunit 1 1233038 5297422 Tmel_1218 Thermosipho melanesiensis BI429 respiratory-chain NADH dehydrogenase subunit 1 YP_001306457.1 1232157 D 391009 CDS YP_001306458.1 150021104 5297423 1233050..1233592 1 NC_009616.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1233592 5297423 Tmel_1219 Thermosipho melanesiensis BI429 NADH dehydrogenase subunit B YP_001306458.1 1233050 D 391009 CDS YP_001306459.1 150021105 5296673 1233573..1234103 1 NC_009616.1 PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit; NADH dehydrogenase (ubiquinone), 30 kDa subunit 1234103 5296673 Tmel_1220 Thermosipho melanesiensis BI429 NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001306459.1 1233573 D 391009 CDS YP_001306460.1 150021106 5296674 1234096..1235199 1 NC_009616.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1235199 5296674 Tmel_1221 Thermosipho melanesiensis BI429 NADH dehydrogenase subunit D YP_001306460.1 1234096 D 391009 CDS YP_001306461.1 150021107 5297376 1235215..1237065 1 NC_009616.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 1237065 5297376 Tmel_1222 Thermosipho melanesiensis BI429 putative oxidoreductase YP_001306461.1 1235215 D 391009 CDS YP_001306462.1 150021108 5297377 1237067..1237570 1 NC_009616.1 hypothetical protein 1237570 5297377 Tmel_1223 Thermosipho melanesiensis BI429 hypothetical protein YP_001306462.1 1237067 D 391009 CDS YP_001306463.1 150021109 5297607 complement(1237579..1238184) 1 NC_009616.1 MobA-like protein 1238184 5297607 Tmel_1224 Thermosipho melanesiensis BI429 MobA-like protein YP_001306463.1 1237579 R 391009 CDS YP_001306464.1 150021110 5298069 1238626..1240551 1 NC_009616.1 PFAM: glycoside hydrolase, family 20; glycoside hydrolase family protein 1240551 5298069 Tmel_1226 Thermosipho melanesiensis BI429 glycoside hydrolase family protein YP_001306464.1 1238626 D 391009 CDS YP_001306465.1 150021111 5297609 1240548..1241291 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1241291 5297609 Tmel_1227 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001306465.1 1240548 D 391009 CDS YP_001306466.1 150021112 5296601 1241288..1241650 1 NC_009616.1 PFAM: transcriptional regulator PadR family protein; PadR-like family transcriptional regulator 1241650 5296601 Tmel_1228 Thermosipho melanesiensis BI429 PadR-like family transcriptional regulator YP_001306466.1 1241288 D 391009 CDS YP_001306467.1 150021113 5296602 1241767..1243107 1 NC_009616.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1243107 5296602 Tmel_1229 Thermosipho melanesiensis BI429 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001306467.1 1241767 D 391009 CDS YP_001306468.1 150021114 5297182 1243344..1243910 1 NC_009616.1 PFAM: transferase hexapeptide repeat containing protein; Serine O-acetyltransferase 1243910 5297182 Tmel_1230 Thermosipho melanesiensis BI429 Serine O-acetyltransferase YP_001306468.1 1243344 D 391009 CDS YP_001306469.1 150021115 5297183 1243923..1244780 1 NC_009616.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta 1244780 5297183 Tmel_1231 Thermosipho melanesiensis BI429 pyridoxal-5'-phosphate-dependent enzyme subunit beta YP_001306469.1 1243923 D 391009 CDS YP_001306470.1 150021116 5297849 1244987..1245439 1 NC_009616.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase, catalytic subunit 1245439 5297849 Tmel_1232 Thermosipho melanesiensis BI429 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_001306470.1 1244987 D 391009 CDS YP_001306471.1 150021117 5297850 1245453..1246139 1 NC_009616.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1246139 5297850 Tmel_1233 Thermosipho melanesiensis BI429 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001306471.1 1245453 D 391009 CDS YP_001306472.1 150021118 5296724 1246115..1246363 1 NC_009616.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; phosphoribosylformylglycinamidine synthase PurS 1246363 5296724 Tmel_1234 Thermosipho melanesiensis BI429 phosphoribosylformylglycinamidine synthase PurS YP_001306472.1 1246115 D 391009 CDS YP_001306473.1 150021119 5296725 1246360..1246992 1 NC_009616.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1246992 5296725 Tmel_1235 Thermosipho melanesiensis BI429 phosphoribosylformylglycinamidine synthase I YP_001306473.1 1246360 D 391009 CDS YP_001306474.1 150021120 5296827 1246989..1248761 1 NC_009616.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1248761 5296827 Tmel_1236 Thermosipho melanesiensis BI429 phosphoribosylformylglycinamidine synthase II YP_001306474.1 1246989 D 391009 CDS YP_001306475.1 150021121 5296828 1248920..1250542 1 NC_009616.1 hypothetical protein 1250542 5296828 Tmel_1237 Thermosipho melanesiensis BI429 hypothetical protein YP_001306475.1 1248920 D 391009 CDS YP_001306476.1 150021122 5296704 1250585..1251337 1 NC_009616.1 hypothetical protein 1251337 5296704 Tmel_1238 Thermosipho melanesiensis BI429 hypothetical protein YP_001306476.1 1250585 D 391009 CDS YP_001306477.1 150021123 5296705 1251409..1252227 1 NC_009616.1 PFAM: Indigoidine synthase A family protein; indigoidine synthase A family protein 1252227 5296705 Tmel_1239 Thermosipho melanesiensis BI429 indigoidine synthase A family protein YP_001306477.1 1251409 D 391009 CDS YP_001306478.1 150021124 5296592 1252326..1252880 1 NC_009616.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 1252880 5296592 Tmel_1240 Thermosipho melanesiensis BI429 phosphodiesterase YP_001306478.1 1252326 D 391009 CDS YP_001306479.1 150021125 5296916 1252877..1253470 1 NC_009616.1 PFAM: protein of unknown function UPF0029; hypothetical protein 1253470 5296916 Tmel_1241 Thermosipho melanesiensis BI429 hypothetical protein YP_001306479.1 1252877 D 391009 CDS YP_001306480.1 150021126 5296917 1253474..1254664 1 NC_009616.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1254664 5296917 Tmel_1242 Thermosipho melanesiensis BI429 aspartate aminotransferase YP_001306480.1 1253474 D 391009 CDS YP_001306481.1 150021127 5296539 complement(1254675..1255958) 1 NC_009616.1 TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; adenylosuccinate lyase 1255958 5296539 Tmel_1243 Thermosipho melanesiensis BI429 adenylosuccinate lyase YP_001306481.1 1254675 R 391009 CDS YP_001306482.1 150021128 5296540 1256066..1256395 1 NC_009616.1 PFAM: regulatory protein, MarR; regulatory protein, ArsR; regulatory protein ArsR 1256395 5296540 Tmel_1244 Thermosipho melanesiensis BI429 regulatory protein ArsR YP_001306482.1 1256066 D 391009 CDS YP_001306483.1 150021129 5297131 1256382..1257266 1 NC_009616.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; cation diffusion facilitator family transporter 1257266 5297131 Tmel_1245 Thermosipho melanesiensis BI429 cation diffusion facilitator family transporter YP_001306483.1 1256382 D 391009 CDS YP_001306484.1 150021130 5298070 complement(1257708..1258166) 1 NC_009616.1 hypothetical protein 1258166 5298070 Tmel_1246 Thermosipho melanesiensis BI429 hypothetical protein YP_001306484.1 1257708 R 391009 CDS YP_001306485.1 150021131 5297437 complement(1258189..1258767) 1 NC_009616.1 hypothetical protein 1258767 5297437 Tmel_1247 Thermosipho melanesiensis BI429 hypothetical protein YP_001306485.1 1258189 R 391009 CDS YP_001306486.1 150021132 5297438 1258924..1259766 1 NC_009616.1 response regulator receiver/SARP domain-containing protein 1259766 5297438 Tmel_1248 Thermosipho melanesiensis BI429 response regulator receiver/SARP domain-containing protein YP_001306486.1 1258924 D 391009 CDS YP_001306487.1 150021133 5297138 complement(1260537..1260869) 1 NC_009616.1 hypothetical protein 1260869 5297138 Tmel_1251 Thermosipho melanesiensis BI429 hypothetical protein YP_001306487.1 1260537 R 391009 CDS YP_001306488.1 150021134 5297367 complement(1260870..1261001) 1 NC_009616.1 hypothetical protein 1261001 5297367 Tmel_1252 Thermosipho melanesiensis BI429 hypothetical protein YP_001306488.1 1260870 R 391009 CDS YP_001306489.1 150021135 5297839 complement(1262626..1263912) 1 NC_009616.1 hypothetical protein 1263912 5297839 Tmel_1255 Thermosipho melanesiensis BI429 hypothetical protein YP_001306489.1 1262626 R 391009 CDS YP_001306490.1 150021136 5297723 complement(1263909..1265018) 1 NC_009616.1 PFAM: Secretin/TonB, short N-terminal domain; secretin/TonB, short N-terminal domain 1265018 5297723 Tmel_1256 Thermosipho melanesiensis BI429 secretin/TonB, short N-terminal domain YP_001306490.1 1263909 R 391009 CDS YP_001306491.1 150021137 5297333 complement(1265015..1266418) 1 NC_009616.1 hypothetical protein 1266418 5297333 Tmel_1257 Thermosipho melanesiensis BI429 hypothetical protein YP_001306491.1 1265015 R 391009 CDS YP_001306492.1 150021138 5297803 1266592..1266954 1 NC_009616.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; putative 6-pyruvoyl tetrahydropterin synthase 1266954 5297803 Tmel_1258 Thermosipho melanesiensis BI429 putative 6-pyruvoyl tetrahydropterin synthase YP_001306492.1 1266592 D 391009 CDS YP_001306493.1 150021139 5297804 1266954..1268072 1 NC_009616.1 PFAM: aminotransferase, class I and II; class I and II aminotransferase 1268072 5297804 Tmel_1259 Thermosipho melanesiensis BI429 class I and II aminotransferase YP_001306493.1 1266954 D 391009 CDS YP_001306494.1 150021140 5297260 complement(1268508..1269989) 1 NC_009616.1 PFAM: cation transporter; cation transporter 1269989 5297260 Tmel_1260 Thermosipho melanesiensis BI429 cation transporter YP_001306494.1 1268508 R 391009 CDS YP_001306495.1 150021141 5297261 complement(1269991..1270650) 1 NC_009616.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; TrkA domain-containing protein 1270650 5297261 Tmel_1261 Thermosipho melanesiensis BI429 TrkA domain-containing protein YP_001306495.1 1269991 R 391009 CDS YP_001306496.1 150021142 5297215 complement(1270647..1271072) 1 NC_009616.1 PFAM: TrkA-N domain protein; TrkA domain-containing protein 1271072 5297215 Tmel_1262 Thermosipho melanesiensis BI429 TrkA domain-containing protein YP_001306496.1 1270647 R 391009 CDS YP_001306497.1 150021143 5297216 complement(1271056..1271649) 1 NC_009616.1 PFAM: response regulator receiver; response regulator receiver protein 1271649 5297216 Tmel_1263 Thermosipho melanesiensis BI429 response regulator receiver protein YP_001306497.1 1271056 R 391009 CDS YP_001306498.1 150021144 5297642 complement(1271700..1272422) 1 NC_009616.1 PFAM: triosephosphate isomerase; Triose-phosphate isomerase 1272422 5297642 Tmel_1264 Thermosipho melanesiensis BI429 Triose-phosphate isomerase YP_001306498.1 1271700 R 391009 CDS YP_001306499.1 150021145 5297643 complement(1272443..1273651) 1 NC_009616.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1273651 pgk 5297643 pgk Thermosipho melanesiensis BI429 phosphoglycerate kinase YP_001306499.1 1272443 R 391009 CDS YP_001306500.1 150021146 5297403 complement(1273719..1274717) 1 NC_009616.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I 1274717 5297403 Tmel_1266 Thermosipho melanesiensis BI429 glyceraldehyde-3-phosphate dehydrogenase, type I YP_001306500.1 1273719 R 391009 CDS YP_001306501.1 150021147 5297404 complement(1274811..1275524) 1 NC_009616.1 hypothetical protein 1275524 5297404 Tmel_1267 Thermosipho melanesiensis BI429 hypothetical protein YP_001306501.1 1274811 R 391009 CDS YP_001306502.1 150021148 5297435 complement(1275537..1276856) 1 NC_009616.1 hypothetical protein 1276856 5297435 Tmel_1268 Thermosipho melanesiensis BI429 hypothetical protein YP_001306502.1 1275537 R 391009 CDS YP_001306503.1 150021149 5297436 complement(1276868..1278172) 1 NC_009616.1 TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase; flagellar protein export ATPase FliI 1278172 5297436 Tmel_1269 Thermosipho melanesiensis BI429 flagellar protein export ATPase FliI YP_001306503.1 1276868 R 391009 CDS YP_001306504.1 150021150 5296543 complement(1278165..1278854) 1 NC_009616.1 hypothetical protein 1278854 5296543 Tmel_1270 Thermosipho melanesiensis BI429 hypothetical protein YP_001306504.1 1278165 R 391009 CDS YP_001306505.1 150021151 5296833 complement(1278894..1280114) 1 NC_009616.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1280114 5296833 Tmel_1271 Thermosipho melanesiensis BI429 acetate kinase YP_001306505.1 1278894 R 391009 CDS YP_001306506.1 150021152 5296834 complement(1280137..1281072) 1 NC_009616.1 TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase, class-II; fructose-1,6-bisphosphate aldolase, class II 1281072 5296834 Tmel_1272 Thermosipho melanesiensis BI429 fructose-1,6-bisphosphate aldolase, class II YP_001306506.1 1280137 R 391009 CDS YP_001306507.1 150021153 5297944 1281476..1281955 1 NC_009616.1 hypothetical protein 1281955 5297944 Tmel_1273 Thermosipho melanesiensis BI429 hypothetical protein YP_001306507.1 1281476 D 391009 CDS YP_001306508.1 150021154 5296719 1281961..1283223 1 NC_009616.1 PFAM: cell division protein FtsA; cell division protein FtsA 1283223 5296719 Tmel_1274 Thermosipho melanesiensis BI429 cell division protein FtsA YP_001306508.1 1281961 D 391009 CDS YP_001306509.1 150021155 5296593 1283226..1284320 1 NC_009616.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1284320 5296593 Tmel_1275 Thermosipho melanesiensis BI429 cell division protein FtsZ YP_001306509.1 1283226 D 391009 CDS YP_001306510.1 150021156 5296594 1284313..1286004 1 NC_009616.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase; type II secretion system protein E 1286004 5296594 Tmel_1276 Thermosipho melanesiensis BI429 type II secretion system protein E YP_001306510.1 1284313 D 391009 CDS YP_001306511.1 150021157 5297618 1285994..1287145 1 NC_009616.1 hypothetical protein 1287145 5297618 Tmel_1277 Thermosipho melanesiensis BI429 hypothetical protein YP_001306511.1 1285994 D 391009 CDS YP_001306512.1 150021158 5297619 1287197..1287754 1 NC_009616.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1287754 frr 5297619 frr Thermosipho melanesiensis BI429 ribosome recycling factor YP_001306512.1 1287197 D 391009 CDS YP_001306513.1 150021159 5297306 1287756..1288433 1 NC_009616.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 1288433 5297306 Tmel_1279 Thermosipho melanesiensis BI429 undecaprenyl diphosphate synthase YP_001306513.1 1287756 D 391009 CDS YP_001306514.1 150021160 5297307 1288430..1289242 1 NC_009616.1 PFAM: phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase 1289242 5297307 Tmel_1280 Thermosipho melanesiensis BI429 phosphatidate cytidylyltransferase YP_001306514.1 1288430 D 391009 CDS YP_001306515.1 150021161 5297172 1289256..1291835 1 NC_009616.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1291835 alaS 5297172 alaS Thermosipho melanesiensis BI429 alanyl-tRNA synthetase YP_001306515.1 1289256 D 391009 CDS YP_001306516.1 150021162 5297173 1291838..1292851 1 NC_009616.1 TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; rod shape-determining protein MreB 1292851 5297173 Tmel_1282 Thermosipho melanesiensis BI429 rod shape-determining protein MreB YP_001306516.1 1291838 D 391009 CDS YP_001306517.1 150021163 5296879 1292848..1293462 1 NC_009616.1 hypothetical protein 1293462 5296879 Tmel_1283 Thermosipho melanesiensis BI429 hypothetical protein YP_001306517.1 1292848 D 391009 CDS YP_001306518.1 150021164 5297778 1293464..1294057 1 NC_009616.1 PFAM: GGDEF domain containing protein; diguanylate cyclase 1294057 5297778 Tmel_1284 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306518.1 1293464 D 391009 CDS YP_001306519.1 150021165 5297779 1294044..1295318 1 NC_009616.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1295318 5297779 Tmel_1285 Thermosipho melanesiensis BI429 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001306519.1 1294044 D 391009 CDS YP_001306520.1 150021166 5297780 1295324..1297108 1 NC_009616.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; polysaccharide biosynthesis protein CapD 1297108 5297780 Tmel_1286 Thermosipho melanesiensis BI429 polysaccharide biosynthesis protein CapD YP_001306520.1 1295324 D 391009 CDS YP_001306521.1 150021167 5297781 1297105..1297611 1 NC_009616.1 hypothetical protein 1297611 5297781 Tmel_1287 Thermosipho melanesiensis BI429 hypothetical protein YP_001306521.1 1297105 D 391009 CDS YP_001306522.1 150021168 5297166 1297621..1297908 1 NC_009616.1 hypothetical protein 1297908 5297166 Tmel_1288 Thermosipho melanesiensis BI429 hypothetical protein YP_001306522.1 1297621 D 391009 CDS YP_001306523.1 150021169 5297167 1297959..1300016 1 NC_009616.1 TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; translation elongation factor G 1300016 5297167 Tmel_1289 Thermosipho melanesiensis BI429 translation elongation factor G YP_001306523.1 1297959 D 391009 CDS YP_001306524.1 150021170 5297025 1300105..1301052 1 NC_009616.1 hypothetical protein 1301052 5297025 Tmel_1290 Thermosipho melanesiensis BI429 hypothetical protein YP_001306524.1 1300105 D 391009 CDS YP_001306525.1 150021171 5297026 1301049..1303259 1 NC_009616.1 hypothetical protein 1303259 5297026 Tmel_1291 Thermosipho melanesiensis BI429 hypothetical protein YP_001306525.1 1301049 D 391009 CDS YP_001306526.1 150021172 5297832 1303234..1303899 1 NC_009616.1 PFAM: flagellar hook capping protein; flagellar hook capping protein 1303899 5297832 Tmel_1292 Thermosipho melanesiensis BI429 flagellar hook capping protein YP_001306526.1 1303234 D 391009 CDS YP_001306527.1 150021173 5297833 1303905..1306022 1 NC_009616.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; hypothetical protein 1306022 5297833 Tmel_1293 Thermosipho melanesiensis BI429 hypothetical protein YP_001306527.1 1303905 D 391009 CDS YP_001306528.1 150021174 5297593 1306031..1306252 1 NC_009616.1 PFAM: flagellar FlbD family protein; flagellar FlbD family protein 1306252 5297593 Tmel_1294 Thermosipho melanesiensis BI429 flagellar FlbD family protein YP_001306528.1 1306031 D 391009 CDS YP_001306529.1 150021175 5297594 1306252..1307040 1 NC_009616.1 PFAM: MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel 1307040 5297594 Tmel_1295 Thermosipho melanesiensis BI429 MotA/TolQ/ExbB proton channel YP_001306529.1 1306252 D 391009 CDS YP_001306530.1 150021176 5297252 1307040..1307906 1 NC_009616.1 flagellar motor protein-like protein 1307906 5297252 Tmel_1296 Thermosipho melanesiensis BI429 flagellar motor protein-like protein YP_001306530.1 1307040 D 391009 CDS YP_001306531.1 150021177 5296597 1307919..1308440 1 NC_009616.1 PFAM: flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 1308440 5296597 Tmel_1297 Thermosipho melanesiensis BI429 flagellar basal body-associated protein FliL YP_001306531.1 1307919 D 391009 CDS YP_001306532.1 150021178 5296598 1308454..1309443 1 NC_009616.1 PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; flagellar motor switch protein FliM 1309443 5296598 Tmel_1298 Thermosipho melanesiensis BI429 flagellar motor switch protein FliM YP_001306532.1 1308454 D 391009 CDS YP_001306533.1 150021179 5297069 1309440..1310552 1 NC_009616.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; CheC, inhibitor of MCP methylation 1310552 5297069 Tmel_1299 Thermosipho melanesiensis BI429 CheC, inhibitor of MCP methylation YP_001306533.1 1309440 D 391009 CDS YP_001306534.1 150021180 5297070 complement(1310688..1312184) 1 NC_009616.1 PFAM: sodium:neurotransmitter symporter; sodium:neurotransmitter symporter 1312184 5297070 Tmel_1300 Thermosipho melanesiensis BI429 sodium:neurotransmitter symporter YP_001306534.1 1310688 R 391009 CDS YP_001306535.1 150021181 5296865 complement(1312319..1313305) 1 NC_009616.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATPase 1313305 5296865 Tmel_1301 Thermosipho melanesiensis BI429 ATPase YP_001306535.1 1312319 R 391009 CDS YP_001306536.1 150021182 5296866 complement(1313292..1313837) 1 NC_009616.1 PFAM: chromosome segregation and condensation protein ScpB; putative transcriptional regulator 1313837 5296866 Tmel_1302 Thermosipho melanesiensis BI429 putative transcriptional regulator YP_001306536.1 1313292 R 391009 CDS YP_001306537.1 150021183 5296671 complement(1313830..1314489) 1 NC_009616.1 PFAM: chromosome segregation and condensation protein ScpA; chromosome segregation and condensation protein ScpA 1314489 5296671 Tmel_1303 Thermosipho melanesiensis BI429 chromosome segregation and condensation protein ScpA YP_001306537.1 1313830 R 391009 CDS YP_001306538.1 150021184 5296672 complement(1314489..1315091) 1 NC_009616.1 PFAM: CBS domain containing protein; amino acid-binding ACT domain protein; signal-transduction protein 1315091 5296672 Tmel_1304 Thermosipho melanesiensis BI429 signal-transduction protein YP_001306538.1 1314489 R 391009 CDS YP_001306539.1 150021185 5297703 complement(1315107..1316051) 1 NC_009616.1 hypothetical protein 1316051 5297703 Tmel_1305 Thermosipho melanesiensis BI429 hypothetical protein YP_001306539.1 1315107 R 391009 CDS YP_001306540.1 150021186 5297704 complement(1316008..1317186) 1 NC_009616.1 TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase 1317186 5297704 Tmel_1306 Thermosipho melanesiensis BI429 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase YP_001306540.1 1316008 R 391009 CDS YP_001306541.1 150021187 5296856 complement(1317188..1317982) 1 NC_009616.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1317982 panB 5296856 panB Thermosipho melanesiensis BI429 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001306541.1 1317188 R 391009 CDS YP_001306542.1 150021188 5296857 complement(1318030..1318770) 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1318770 5296857 Tmel_1308 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001306542.1 1318030 R 391009 CDS YP_001306543.1 150021189 5297368 1318833..1319795 1 NC_009616.1 PFAM: polysaccharide pyruvyl transferase; polysaccharide pyruvyl transferase 1319795 5297368 Tmel_1309 Thermosipho melanesiensis BI429 polysaccharide pyruvyl transferase YP_001306543.1 1318833 D 391009 CDS YP_001306544.1 150021190 5297678 complement(1319785..1320549) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1320549 5297678 Tmel_1310 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306544.1 1319785 R 391009 CDS YP_001306545.1 150021191 5297679 complement(1320533..1321066) 1 NC_009616.1 PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase 1321066 5297679 Tmel_1311 Thermosipho melanesiensis BI429 lytic transglycosylase YP_001306545.1 1320533 R 391009 CDS YP_001306546.1 150021192 5297327 complement(1321077..1321418) 1 NC_009616.1 PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; acid phosphatase/vanadium-dependent haloperoxidase related 1321418 5297327 Tmel_1312 Thermosipho melanesiensis BI429 acid phosphatase/vanadium-dependent haloperoxidase related YP_001306546.1 1321077 R 391009 CDS YP_001306547.1 150021193 5297328 complement(1321427..1321834) 1 NC_009616.1 putative anti-sigma regulatory factor, serine/threonine protein kinase 1321834 5297328 Tmel_1313 Thermosipho melanesiensis BI429 putative anti-sigma regulatory factor, serine/threonine protein kinase YP_001306547.1 1321427 R 391009 CDS YP_001306548.1 150021194 5297449 complement(1321834..1322625) 1 NC_009616.1 PFAM: protein of unknown function DUF208; hypothetical protein 1322625 5297449 Tmel_1314 Thermosipho melanesiensis BI429 hypothetical protein YP_001306548.1 1321834 R 391009 CDS YP_001306549.1 150021195 5297450 complement(1322625..1323077) 1 NC_009616.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1323077 5297450 Tmel_1315 Thermosipho melanesiensis BI429 D-tyrosyl-tRNA(Tyr) deacylase YP_001306549.1 1322625 R 391009 CDS YP_001306550.1 150021196 5296933 complement(1323074..1325200) 1 NC_009616.1 TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region; (p)ppGpp synthetase I SpoT/RelA 1325200 5296933 Tmel_1316 Thermosipho melanesiensis BI429 (p)ppGpp synthetase I SpoT/RelA YP_001306550.1 1323074 R 391009 CDS YP_001306551.1 150021197 5296934 1325318..1326637 1 NC_009616.1 hypothetical protein 1326637 5296934 Tmel_1317 Thermosipho melanesiensis BI429 hypothetical protein YP_001306551.1 1325318 D 391009 CDS YP_001306552.1 150021198 5297680 1326637..1328115 1 NC_009616.1 PFAM: peptidase C1A, papain; peptidase C1A, papain 1328115 5297680 Tmel_1318 Thermosipho melanesiensis BI429 peptidase C1A, papain YP_001306552.1 1326637 D 391009 CDS YP_001306553.1 150021199 5297681 complement(1328152..1330458) 1 NC_009616.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 1330458 5297681 Tmel_1319 Thermosipho melanesiensis BI429 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_001306553.1 1328152 R 391009 CDS YP_001306554.1 150021200 5297245 complement(1330458..1330901) 1 NC_009616.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; 2Fe-2S iron-sulfur cluster binding domain-containing protein 1330901 5297245 Tmel_1320 Thermosipho melanesiensis BI429 2Fe-2S iron-sulfur cluster binding domain-containing protein YP_001306554.1 1330458 R 391009 CDS YP_001306555.1 150021201 5297246 complement(1330901..1331659) 1 NC_009616.1 PFAM: molybdopterin dehydrogenase, FAD-binding; FAD-binding molybdopterin dehydrogenase 1331659 5297246 Tmel_1321 Thermosipho melanesiensis BI429 FAD-binding molybdopterin dehydrogenase YP_001306555.1 1330901 R 391009 CDS YP_001306556.1 150021202 5297736 complement(1331664..1332494) 1 NC_009616.1 PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein; FAD-binding molybdopterin dehydrogenase 1332494 5297736 Tmel_1322 Thermosipho melanesiensis BI429 FAD-binding molybdopterin dehydrogenase YP_001306556.1 1331664 R 391009 CDS YP_001306557.1 150021203 5297362 complement(1332487..1332942) 1 NC_009616.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; 2Fe-2S iron-sulfur cluster binding domain-containing protein 1332942 5297362 Tmel_1323 Thermosipho melanesiensis BI429 2Fe-2S iron-sulfur cluster binding domain-containing protein YP_001306557.1 1332487 R 391009 CDS YP_001306558.1 150021204 5297363 complement(1332939..1334147) 1 NC_009616.1 TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; threonine synthase 1334147 5297363 Tmel_1324 Thermosipho melanesiensis BI429 threonine synthase YP_001306558.1 1332939 R 391009 CDS YP_001306559.1 150021205 5297067 1334295..1334837 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1334837 5297067 Tmel_1325 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306559.1 1334295 D 391009 CDS YP_001306560.1 150021206 5297068 1334834..1335238 1 NC_009616.1 hypothetical protein 1335238 5297068 Tmel_1326 Thermosipho melanesiensis BI429 hypothetical protein YP_001306560.1 1334834 D 391009 CDS YP_001306561.1 150021207 5296902 1335251..1337161 1 NC_009616.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1337161 thrS 5296902 thrS Thermosipho melanesiensis BI429 threonyl-tRNA synthetase YP_001306561.1 1335251 D 391009 CDS YP_001306562.1 150021208 5296903 1337166..1337972 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1337972 5296903 Tmel_1328 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306562.1 1337166 D 391009 CDS YP_001306563.1 150021209 5297693 1337999..1338409 1 NC_009616.1 PFAM: protein of unknown function DUF107; hypothetical protein 1338409 5297693 Tmel_1329 Thermosipho melanesiensis BI429 hypothetical protein YP_001306563.1 1337999 D 391009 CDS YP_001306564.1 150021210 5297694 1338409..1339323 1 NC_009616.1 PFAM: band 7 protein; hypothetical protein 1339323 5297694 Tmel_1330 Thermosipho melanesiensis BI429 hypothetical protein YP_001306564.1 1338409 D 391009 CDS YP_001306565.1 150021211 5297186 1339316..1339795 1 NC_009616.1 hypothetical protein 1339795 5297186 Tmel_1331 Thermosipho melanesiensis BI429 hypothetical protein YP_001306565.1 1339316 D 391009 CDS YP_001306566.1 150021212 5297187 1339810..1340934 1 NC_009616.1 hypothetical protein 1340934 5297187 Tmel_1332 Thermosipho melanesiensis BI429 hypothetical protein YP_001306566.1 1339810 D 391009 CDS YP_001306567.1 150021213 5297891 1341049..1342209 1 NC_009616.1 PFAM: Orn/DAP/Arg decarboxylase 2; Orn/DAP/Arg decarboxylase 2 1342209 5297891 Tmel_1333 Thermosipho melanesiensis BI429 Orn/DAP/Arg decarboxylase 2 YP_001306567.1 1341049 D 391009 CDS YP_001306568.1 150021214 5297748 1342361..1343086 1 NC_009616.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; WecB/TagA/CpsF family glycosyl transferase 1343086 5297748 Tmel_1334 Thermosipho melanesiensis BI429 WecB/TagA/CpsF family glycosyl transferase YP_001306568.1 1342361 D 391009 CDS YP_001306569.1 150021215 5297972 1343083..1343712 1 NC_009616.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; methyltransferase GidB 1343712 5297972 Tmel_1335 Thermosipho melanesiensis BI429 methyltransferase GidB YP_001306569.1 1343083 D 391009 CDS YP_001306570.1 150021216 5297815 1343725..1345050 1 NC_009616.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1345050 trmE 5297815 trmE Thermosipho melanesiensis BI429 tRNA modification GTPase TrmE YP_001306570.1 1343725 D 391009 CDS YP_001306571.1 150021217 5297816 complement(1345304..1345978) 1 NC_009616.1 PFAM: protein of unknown function DUF124; hypothetical protein 1345978 5297816 Tmel_1337 Thermosipho melanesiensis BI429 hypothetical protein YP_001306571.1 1345304 R 391009 CDS YP_001306572.1 150021218 5297620 1346040..1346813 1 NC_009616.1 hypothetical protein 1346813 5297620 Tmel_1338 Thermosipho melanesiensis BI429 hypothetical protein YP_001306572.1 1346040 D 391009 CDS YP_001306573.1 150021219 5297621 complement(1346808..1348112) 1 NC_009616.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like; UDP-glucose 6-dehydrogenase 1348112 5297621 Tmel_1339 Thermosipho melanesiensis BI429 UDP-glucose 6-dehydrogenase YP_001306573.1 1346808 R 391009 CDS YP_001306574.1 150021220 5298248 1348257..1348871 1 NC_009616.1 PFAM: phosphoesterase, PA-phosphatase related; PA-phosphatase-like phosphoesterase 1348871 5298248 Tmel_1340 Thermosipho melanesiensis BI429 PA-phosphatase-like phosphoesterase YP_001306574.1 1348257 D 391009 CDS YP_001306575.1 150021221 5298249 1348949..1350103 1 NC_009616.1 PFAM: major facilitator superfamily MFS_1; major facilitator transporter 1350103 5298249 Tmel_1341 Thermosipho melanesiensis BI429 major facilitator transporter YP_001306575.1 1348949 D 391009 CDS YP_001306576.1 150021222 5298332 1350131..1351030 1 NC_009616.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9 prolyl oligopeptidase 1351030 5298332 Tmel_1342 Thermosipho melanesiensis BI429 peptidase S9 prolyl oligopeptidase YP_001306576.1 1350131 D 391009 CDS YP_001306577.1 150021223 5298333 1351023..1352012 1 NC_009616.1 hypothetical protein 1352012 5298333 Tmel_1343 Thermosipho melanesiensis BI429 hypothetical protein YP_001306577.1 1351023 D 391009 CDS YP_001306578.1 150021224 5297455 complement(1352013..1353410) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 1353410 5297455 Tmel_1344 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306578.1 1352013 R 391009 CDS YP_001306579.1 150021225 5297456 1353591..1354286 1 NC_009616.1 PFAM: glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 1354286 5297456 Tmel_1345 Thermosipho melanesiensis BI429 glycerophosphoryl diester phosphodiesterase YP_001306579.1 1353591 D 391009 CDS YP_001306580.1 150021226 5297577 complement(1354295..1355470) 1 NC_009616.1 TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative; PFAM: glycine hydroxymethyltransferase; aminotransferase, class I and II; aminotransferase class-III; pyridoxal phosphate-dependent acyltransferase 1355470 5297577 Tmel_1346 Thermosipho melanesiensis BI429 pyridoxal phosphate-dependent acyltransferase YP_001306580.1 1354295 R 391009 CDS YP_001306581.1 150021227 5297578 complement(1355482..1356513) 1 NC_009616.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase 1356513 5297578 Tmel_1347 Thermosipho melanesiensis BI429 alcohol dehydrogenase YP_001306581.1 1355482 R 391009 CDS YP_001306582.1 150021228 5297958 complement(1356635..1357342) 1 NC_009616.1 hypothetical protein 1357342 5297958 Tmel_1348 Thermosipho melanesiensis BI429 hypothetical protein YP_001306582.1 1356635 R 391009 CDS YP_001306583.1 150021229 5298428 complement(1357699..1357866) 1 NC_009616.1 hypothetical protein 1357866 5298428 Tmel_1349 Thermosipho melanesiensis BI429 hypothetical protein YP_001306583.1 1357699 R 391009 CDS YP_001306584.1 150021230 5298429 complement(1357940..1358119) 1 NC_009616.1 hypothetical protein 1358119 5298429 Tmel_1350 Thermosipho melanesiensis BI429 hypothetical protein YP_001306584.1 1357940 R 391009 CDS YP_001306585.1 150021231 5297947 complement(1358161..1358613) 1 NC_009616.1 hypothetical protein 1358613 5297947 Tmel_1351 Thermosipho melanesiensis BI429 hypothetical protein YP_001306585.1 1358161 R 391009 CDS YP_001306586.1 150021232 5297486 1359094..1360455 1 NC_009616.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; MATE efflux family protein 1360455 5297486 Tmel_1353 Thermosipho melanesiensis BI429 MATE efflux family protein YP_001306586.1 1359094 D 391009 CDS YP_001306587.1 150021233 5298432 1360495..1361337 1 NC_009616.1 hypothetical protein 1361337 5298432 Tmel_1354 Thermosipho melanesiensis BI429 hypothetical protein YP_001306587.1 1360495 D 391009 CDS YP_001306588.1 150021234 5298433 complement(1361445..1362251) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1362251 5298433 Tmel_1355 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306588.1 1361445 R 391009 CDS YP_001306589.1 150021235 5298455 complement(1362238..1362783) 1 NC_009616.1 hypothetical protein 1362783 5298455 Tmel_1356 Thermosipho melanesiensis BI429 hypothetical protein YP_001306589.1 1362238 R 391009 CDS YP_001306590.1 150021236 5298456 complement(1362770..1363132) 1 NC_009616.1 PFAM: regulatory protein GntR, HTH; regulatory protein GntR 1363132 5298456 Tmel_1357 Thermosipho melanesiensis BI429 regulatory protein GntR YP_001306590.1 1362770 R 391009 CDS YP_001306591.1 150021237 5296678 complement(1363137..1364156) 1 NC_009616.1 hypothetical protein 1364156 5296678 Tmel_1358 Thermosipho melanesiensis BI429 hypothetical protein YP_001306591.1 1363137 R 391009 CDS YP_001306592.1 150021238 5297487 complement(1365054..1366418) 1 NC_009616.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1366418 aspA 5297487 aspA Thermosipho melanesiensis BI429 aspartate ammonia-lyase YP_001306592.1 1365054 R 391009 CDS YP_001306593.1 150021239 5297817 complement(1366423..1367613) 1 NC_009616.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; small GTP-binding protein 1367613 5297817 Tmel_1361 Thermosipho melanesiensis BI429 small GTP-binding protein YP_001306593.1 1366423 R 391009 CDS YP_001306594.1 150021240 5297818 1367754..1368380 1 NC_009616.1 hypothetical protein 1368380 5297818 Tmel_1362 Thermosipho melanesiensis BI429 hypothetical protein YP_001306594.1 1367754 D 391009 CDS YP_001306595.1 150021241 5297978 1368370..1369368 1 NC_009616.1 PFAM: Polyprenyl synthetase; polyprenyl synthetase 1369368 5297978 Tmel_1363 Thermosipho melanesiensis BI429 polyprenyl synthetase YP_001306595.1 1368370 D 391009 CDS YP_001306596.1 150021242 5297867 1369370..1369915 1 NC_009616.1 hypothetical protein 1369915 5297867 Tmel_1364 Thermosipho melanesiensis BI429 hypothetical protein YP_001306596.1 1369370 D 391009 CDS YP_001306597.1 150021243 5297868 1369920..1370534 1 NC_009616.1 TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; uridine kinase 1370534 5297868 Tmel_1365 Thermosipho melanesiensis BI429 uridine kinase YP_001306597.1 1369920 D 391009 CDS YP_001306598.1 150021244 5298259 1370550..1372055 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1372055 5298259 Tmel_1366 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306598.1 1370550 D 391009 CDS YP_001306599.1 150021245 5298260 1372057..1372800 1 NC_009616.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1372800 5298260 Tmel_1367 Thermosipho melanesiensis BI429 pantothenate kinase YP_001306599.1 1372057 D 391009 CDS YP_001306600.1 150021246 5298233 1372781..1374130 1 NC_009616.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1374130 5298233 Tmel_1368 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306600.1 1372781 D 391009 CDS YP_001306601.1 150021247 5298234 1374114..1374734 1 NC_009616.1 PFAM: peptidase M50; peptidase M50 1374734 5298234 Tmel_1369 Thermosipho melanesiensis BI429 peptidase M50 YP_001306601.1 1374114 D 391009 CDS YP_001306602.1 150021248 5298426 1374737..1374988 1 NC_009616.1 hypothetical protein 1374988 5298426 Tmel_1370 Thermosipho melanesiensis BI429 hypothetical protein YP_001306602.1 1374737 D 391009 CDS YP_001306603.1 150021249 5298427 1374963..1375220 1 NC_009616.1 hypothetical protein 1375220 5298427 Tmel_1371 Thermosipho melanesiensis BI429 hypothetical protein YP_001306603.1 1374963 D 391009 CDS YP_001306604.1 150021250 5298374 1375201..1375992 1 NC_009616.1 TIGRFAM: glutamate racemase; PFAM: Asp/Glu racemase; glutamate racemase 1375992 5298374 Tmel_1372 Thermosipho melanesiensis BI429 glutamate racemase YP_001306604.1 1375201 D 391009 CDS YP_001306605.1 150021251 5298375 1375946..1376782 1 NC_009616.1 PFAM: uncharacterised P-loop ATPase protein UPF0042; hypothetical protein 1376782 5298375 Tmel_1373 Thermosipho melanesiensis BI429 hypothetical protein YP_001306605.1 1375946 D 391009 CDS YP_001306606.1 150021252 5298312 1376782..1377714 1 NC_009616.1 PFAM: protein of unknown function UPF0052 and CofD; hypothetical protein 1377714 5298312 Tmel_1374 Thermosipho melanesiensis BI429 hypothetical protein YP_001306606.1 1376782 D 391009 CDS YP_001306607.1 150021253 5298313 1377719..1378630 1 NC_009616.1 PFAM: protein of unknown function DUF199; hypothetical protein 1378630 5298313 Tmel_1375 Thermosipho melanesiensis BI429 hypothetical protein YP_001306607.1 1377719 D 391009 CDS YP_001306608.1 150021254 5298315 1378635..1379090 1 NC_009616.1 PFAM: ATP-cone domain protein; transcriptional regulator NrdR 1379090 nrdR 5298315 nrdR Thermosipho melanesiensis BI429 transcriptional regulator NrdR YP_001306608.1 1378635 D 391009 CDS YP_001306609.1 150021255 5298250 1379107..1379577 1 NC_009616.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1379577 greA 5298250 greA Thermosipho melanesiensis BI429 transcription elongation factor GreA YP_001306609.1 1379107 D 391009 CDS YP_001306610.1 150021256 5298251 1379590..1381098 1 NC_009616.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1381098 lysS 5298251 lysS Thermosipho melanesiensis BI429 lysyl-tRNA synthetase YP_001306610.1 1379590 D 391009 CDS YP_001306611.1 150021257 5298091 1381095..1382705 1 NC_009616.1 hypothetical protein 1382705 5298091 Tmel_1379 Thermosipho melanesiensis BI429 hypothetical protein YP_001306611.1 1381095 D 391009 CDS YP_001306612.1 150021258 5298092 1382790..1383023 1 NC_009616.1 PFAM: RNA-binding S4 domain protein; RNA-binding S4 domain-containing protein 1383023 5298092 Tmel_1380 Thermosipho melanesiensis BI429 RNA-binding S4 domain-containing protein YP_001306612.1 1382790 D 391009 CDS YP_001306613.1 150021259 5298018 1383020..1383934 1 NC_009616.1 GAF domain-containing protein 1383934 5298018 Tmel_1381 Thermosipho melanesiensis BI429 GAF domain-containing protein YP_001306613.1 1383020 D 391009 CDS YP_001306614.1 150021260 5298019 1383946..1385682 1 NC_009616.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1385682 5298019 Tmel_1382 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306614.1 1383946 D 391009 CDS YP_001306615.1 150021261 5297244 1386244..1386684 1 NC_009616.1 hypothetical protein 1386684 5297244 Tmel_1383 Thermosipho melanesiensis BI429 hypothetical protein YP_001306615.1 1386244 D 391009 CDS YP_001306616.1 150021262 5298147 1386704..1387714 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1387714 5298147 Tmel_1384 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306616.1 1386704 D 391009 CDS YP_001306617.1 150021263 5298261 1387707..1388714 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1388714 5298261 Tmel_1385 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306617.1 1387707 D 391009 CDS YP_001306618.1 150021264 5298262 1388719..1390455 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 1390455 5298262 Tmel_1386 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306618.1 1388719 D 391009 CDS YP_001306619.1 150021265 5298046 1390518..1391483 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1391483 5298046 Tmel_1387 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306619.1 1390518 D 391009 CDS YP_001306620.1 150021266 5298047 1391497..1393125 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1393125 5298047 Tmel_1388 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306620.1 1391497 D 391009 CDS YP_001306621.1 150021267 5297557 complement(1393428..1393895) 1 NC_009616.1 HAD superfamily hydrolase-like protein 1393895 5297557 Tmel_1389 Thermosipho melanesiensis BI429 HAD superfamily hydrolase-like protein YP_001306621.1 1393428 R 391009 CDS YP_001306622.1 150021268 5297991 complement(1393908..1394411) 1 NC_009616.1 hypothetical protein 1394411 5297991 Tmel_1390 Thermosipho melanesiensis BI429 hypothetical protein YP_001306622.1 1393908 R 391009 CDS YP_001306623.1 150021269 5297992 complement(1394411..1394965) 1 NC_009616.1 hypothetical protein 1394965 5297992 Tmel_1391 Thermosipho melanesiensis BI429 hypothetical protein YP_001306623.1 1394411 R 391009 CDS YP_001306624.1 150021270 5298451 complement(1394995..1396047) 1 NC_009616.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein 1396047 5298451 Tmel_1392 Thermosipho melanesiensis BI429 TPR repeat-containing protein YP_001306624.1 1394995 R 391009 CDS YP_001306625.1 150021271 5298452 complement(1396049..1397320) 1 NC_009616.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1397320 rho 5298452 rho Thermosipho melanesiensis BI429 transcription termination factor Rho YP_001306625.1 1396049 R 391009 CDS YP_001306626.1 150021272 5298370 complement(1397332..1397958) 1 NC_009616.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1397958 upp 5298370 upp Thermosipho melanesiensis BI429 uracil phosphoribosyltransferase YP_001306626.1 1397332 R 391009 CDS YP_001306627.1 150021273 5298371 complement(1397948..1399024) 1 NC_009616.1 TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; peptide chain release factor 1 1399024 5298371 Tmel_1395 Thermosipho melanesiensis BI429 peptide chain release factor 1 YP_001306627.1 1397948 R 391009 CDS YP_001306628.1 150021274 5298339 complement(1399006..1400073) 1 NC_009616.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; twitching motility protein 1400073 5298339 Tmel_1396 Thermosipho melanesiensis BI429 twitching motility protein YP_001306628.1 1399006 R 391009 CDS YP_001306629.1 150021275 5298340 complement(1400075..1401457) 1 NC_009616.1 TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; DNA polymerase III subunits gamma and tau 1401457 5298340 Tmel_1397 Thermosipho melanesiensis BI429 DNA polymerase III subunits gamma and tau YP_001306629.1 1400075 R 391009 CDS YP_001306630.1 150021276 5298325 complement(1401460..1402365) 1 NC_009616.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1402365 miaA 5298325 miaA Thermosipho melanesiensis BI429 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001306630.1 1401460 R 391009 CDS YP_001306631.1 150021277 5298326 complement(1402369..1402992) 1 NC_009616.1 hypothetical protein 1402992 5298326 Tmel_1399 Thermosipho melanesiensis BI429 hypothetical protein YP_001306631.1 1402369 R 391009 CDS YP_001306632.1 150021278 5298077 complement(1402989..1403720) 1 NC_009616.1 hypothetical protein 1403720 5298077 Tmel_1400 Thermosipho melanesiensis BI429 hypothetical protein YP_001306632.1 1402989 R 391009 CDS YP_001306633.1 150021279 5298078 complement(1403698..1404492) 1 NC_009616.1 PFAM: Patatin; patatin 1404492 5298078 Tmel_1401 Thermosipho melanesiensis BI429 patatin YP_001306633.1 1403698 R 391009 CDS YP_001306634.1 150021280 5298024 complement(1404489..1405340) 1 NC_009616.1 TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2; apurinic endonuclease Apn1 1405340 5298024 Tmel_1402 Thermosipho melanesiensis BI429 apurinic endonuclease Apn1 YP_001306634.1 1404489 R 391009 CDS YP_001306635.1 150021281 5298085 complement(1405333..1405668) 1 NC_009616.1 PFAM: protein of unknown function DUF1622; hypothetical protein 1405668 5298085 Tmel_1403 Thermosipho melanesiensis BI429 hypothetical protein YP_001306635.1 1405333 R 391009 CDS YP_001306636.1 150021282 5298086 complement(1405673..1407397) 1 NC_009616.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1407397 5298086 Tmel_1404 Thermosipho melanesiensis BI429 NAD synthetase YP_001306636.1 1405673 R 391009 CDS YP_001306637.1 150021283 5298376 1407487..1408113 1 NC_009616.1 hypothetical protein 1408113 5298376 Tmel_1405 Thermosipho melanesiensis BI429 hypothetical protein YP_001306637.1 1407487 D 391009 CDS YP_001306638.1 150021284 5298377 1408101..1408703 1 NC_009616.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 1408703 5298377 Tmel_1406 Thermosipho melanesiensis BI429 putative monovalent cation/H+ antiporter subunit B YP_001306638.1 1408101 D 391009 CDS YP_001306639.1 150021285 5298398 1408713..1410017 1 NC_009616.1 hypothetical protein 1410017 5298398 Tmel_1407 Thermosipho melanesiensis BI429 hypothetical protein YP_001306639.1 1408713 D 391009 CDS YP_001306640.1 150021286 5298399 1410014..1410883 1 NC_009616.1 PFAM: prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 1410883 5298399 Tmel_1408 Thermosipho melanesiensis BI429 prolipoprotein diacylglyceryl transferase YP_001306640.1 1410014 D 391009 CDS YP_001306641.1 150021287 5298026 1410880..1412088 1 NC_009616.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; cofactor-independent phosphoglycerate mutase 1412088 5298026 Tmel_1409 Thermosipho melanesiensis BI429 cofactor-independent phosphoglycerate mutase YP_001306641.1 1410880 D 391009 CDS YP_001306642.1 150021288 5298027 1412090..1413304 1 NC_009616.1 PFAM: ComEC/Rec2-related protein; ComEC/Rec2-like protein 1413304 5298027 Tmel_1410 Thermosipho melanesiensis BI429 ComEC/Rec2-like protein YP_001306642.1 1412090 D 391009 CDS YP_001306643.1 150021289 5298191 complement(1413217..1413669) 1 NC_009616.1 PFAM: ferric-uptake regulator; ferric uptake regulator family protein 1413669 5298191 Tmel_1411 Thermosipho melanesiensis BI429 ferric uptake regulator family protein YP_001306643.1 1413217 R 391009 CDS YP_001306644.1 150021290 5298192 complement(1413685..1414719) 1 NC_009616.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1414719 nusA 5298192 nusA Thermosipho melanesiensis BI429 transcription elongation factor NusA YP_001306644.1 1413685 R 391009 CDS YP_001306645.1 150021291 5298184 complement(1414732..1415175) 1 NC_009616.1 PFAM: protein of unknown function DUF150; hypothetical protein 1415175 5298184 Tmel_1413 Thermosipho melanesiensis BI429 hypothetical protein YP_001306645.1 1414732 R 391009 CDS YP_001306646.1 150021292 5297979 1415419..1415688 1 NC_009616.1 PFAM: protein of unknown function DUF861, cupin_3; hypothetical protein 1415688 5297979 Tmel_1414 Thermosipho melanesiensis BI429 hypothetical protein YP_001306646.1 1415419 D 391009 CDS YP_001306647.1 150021293 5298164 1415711..1416334 1 NC_009616.1 PFAM: Formiminotransferase-cyclodeaminase; formiminotransferase-cyclodeaminase 1416334 5298164 Tmel_1415 Thermosipho melanesiensis BI429 formiminotransferase-cyclodeaminase YP_001306647.1 1415711 D 391009 CDS YP_001306648.1 150021294 5297502 1416318..1417421 1 NC_009616.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1417421 tgt 5297502 tgt Thermosipho melanesiensis BI429 queuine tRNA-ribosyltransferase YP_001306648.1 1416318 D 391009 CDS YP_001306649.1 150021295 5297503 1417414..1418193 1 NC_009616.1 hypothetical protein 1418193 5297503 Tmel_1417 Thermosipho melanesiensis BI429 hypothetical protein YP_001306649.1 1417414 D 391009 CDS YP_001306650.1 150021296 5298059 1418194..1418724 1 NC_009616.1 PFAM: phosphoribosyltransferase; Uracil phosphoribosyltransferase 1418724 5298059 Tmel_1418 Thermosipho melanesiensis BI429 Uracil phosphoribosyltransferase YP_001306650.1 1418194 D 391009 CDS YP_001306651.1 150021297 5298060 1418721..1420007 1 NC_009616.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1420007 glmM 5298060 glmM Thermosipho melanesiensis BI429 phosphoglucosamine mutase YP_001306651.1 1418721 D 391009 CDS YP_001306652.1 150021298 5298033 1420012..1420317 1 NC_009616.1 PFAM: protein of unknown function DUF59; hypothetical protein 1420317 5298033 Tmel_1420 Thermosipho melanesiensis BI429 hypothetical protein YP_001306652.1 1420012 D 391009 CDS YP_001306653.1 150021299 5298034 1420314..1421099 1 NC_009616.1 TIGRFAM: modification methylase, HemK family; HemK family modification methylase 1421099 5298034 Tmel_1421 Thermosipho melanesiensis BI429 HemK family modification methylase YP_001306653.1 1420314 D 391009 CDS YP_001306654.1 150021300 5297370 1421105..1421560 1 NC_009616.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1421560 rplI 5297370 rplI Thermosipho melanesiensis BI429 50S ribosomal protein L9 YP_001306654.1 1421105 D 391009 CDS YP_001306655.1 150021301 5297371 1421557..1422396 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1422396 5297371 Tmel_1423 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001306655.1 1421557 D 391009 CDS YP_001306656.1 150021302 5296549 1422408..1423583 1 NC_009616.1 PFAM: metallophosphoesterase; metallophosphoesterase 1423583 5296549 Tmel_1424 Thermosipho melanesiensis BI429 metallophosphoesterase YP_001306656.1 1422408 D 391009 CDS YP_001306657.1 150021303 5296550 1423580..1426159 1 NC_009616.1 PFAM: CBS domain containing protein; phosphoesterase, RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase, DHHA1; CBS domain-containing protein 1426159 5296550 Tmel_1425 Thermosipho melanesiensis BI429 CBS domain-containing protein YP_001306657.1 1423580 D 391009 CDS YP_001306658.1 150021304 5296768 1426156..1427304 1 NC_009616.1 hypothetical protein 1427304 5296768 Tmel_1426 Thermosipho melanesiensis BI429 hypothetical protein YP_001306658.1 1426156 D 391009 CDS YP_001306659.1 150021305 5297057 complement(1427293..1428210) 1 NC_009616.1 hypothetical protein 1428210 5297057 Tmel_1427 Thermosipho melanesiensis BI429 hypothetical protein YP_001306659.1 1427293 R 391009 CDS YP_001306660.1 150021306 5297058 complement(1428207..1428884) 1 NC_009616.1 hypothetical protein 1428884 5297058 Tmel_1428 Thermosipho melanesiensis BI429 hypothetical protein YP_001306660.1 1428207 R 391009 CDS YP_001306661.1 150021307 5297208 complement(1428872..1429315) 1 NC_009616.1 hypothetical protein 1429315 5297208 Tmel_1429 Thermosipho melanesiensis BI429 hypothetical protein YP_001306661.1 1428872 R 391009 CDS YP_001306662.1 150021308 5297209 complement(1429312..1429614) 1 NC_009616.1 hypothetical protein 1429614 5297209 Tmel_1430 Thermosipho melanesiensis BI429 hypothetical protein YP_001306662.1 1429312 R 391009 CDS YP_001306663.1 150021309 5297292 complement(1429618..1430298) 1 NC_009616.1 TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; RNA polymerase sigma-28 subunit FliA/WhiG 1430298 5297292 Tmel_1431 Thermosipho melanesiensis BI429 RNA polymerase sigma-28 subunit FliA/WhiG YP_001306663.1 1429618 R 391009 CDS YP_001306664.1 150021310 5297293 complement(1430295..1430777) 1 NC_009616.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD 1430777 5297293 Tmel_1432 Thermosipho melanesiensis BI429 chemoreceptor glutamine deamidase CheD YP_001306664.1 1430295 R 391009 CDS YP_001306665.1 150021311 5297213 complement(1430777..1431394) 1 NC_009616.1 PFAM: CheC domain protein; CheC, inhibitor of MCP methylation 1431394 5297213 Tmel_1433 Thermosipho melanesiensis BI429 CheC, inhibitor of MCP methylation YP_001306665.1 1430777 R 391009 CDS YP_001306666.1 150021312 5297214 complement(1431405..1432067) 1 NC_009616.1 PFAM: type IV pilus assembly PilZ; type IV pilus assembly PilZ 1432067 5297214 Tmel_1434 Thermosipho melanesiensis BI429 type IV pilus assembly PilZ YP_001306666.1 1431405 R 391009 CDS YP_001306667.1 150021313 5296576 complement(1432082..1432615) 1 NC_009616.1 hypothetical protein 1432615 5296576 Tmel_1435 Thermosipho melanesiensis BI429 hypothetical protein YP_001306667.1 1432082 R 391009 CDS YP_001306668.1 150021314 5296577 complement(1432616..1433446) 1 NC_009616.1 PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 1433446 5296577 Tmel_1436 Thermosipho melanesiensis BI429 cobyrinic acid a,c-diamide synthase YP_001306668.1 1432616 R 391009 CDS YP_001306669.1 150021315 5296744 complement(1433430..1434551) 1 NC_009616.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 1434551 flhF 5296744 flhF Thermosipho melanesiensis BI429 flagellar biosynthesis regulator FlhF YP_001306669.1 1433430 R 391009 CDS YP_001306670.1 150021316 5296745 complement(1434548..1436590) 1 NC_009616.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; flagellar biosynthesis protein FlhA 1436590 5296745 Tmel_1438 Thermosipho melanesiensis BI429 flagellar biosynthesis protein FlhA YP_001306670.1 1434548 R 391009 CDS YP_001306671.1 150021317 5296936 complement(1437133..1437531) 1 NC_009616.1 hypothetical protein 1437531 5296936 Tmel_1439 Thermosipho melanesiensis BI429 hypothetical protein YP_001306671.1 1437133 R 391009 CDS YP_001306672.1 150021318 5296792 complement(1437536..1437817) 1 NC_009616.1 hypothetical protein 1437817 5296792 Tmel_1440 Thermosipho melanesiensis BI429 hypothetical protein YP_001306672.1 1437536 R 391009 CDS YP_001306673.1 150021319 5296793 complement(1437807..1438001) 1 NC_009616.1 hypothetical protein 1438001 5296793 Tmel_1441 Thermosipho melanesiensis BI429 hypothetical protein YP_001306673.1 1437807 R 391009 CDS YP_001306674.1 150021320 5297247 complement(1438003..1438332) 1 NC_009616.1 hypothetical protein 1438332 5297247 Tmel_1442 Thermosipho melanesiensis BI429 hypothetical protein YP_001306674.1 1438003 R 391009 CDS YP_001306675.1 150021321 5297248 complement(1438307..1438549) 1 NC_009616.1 hypothetical protein 1438549 5297248 Tmel_1443 Thermosipho melanesiensis BI429 hypothetical protein YP_001306675.1 1438307 R 391009 CDS YP_001306676.1 150021322 5296605 complement(1438554..1439042) 1 NC_009616.1 hypothetical protein 1439042 5296605 Tmel_1444 Thermosipho melanesiensis BI429 hypothetical protein YP_001306676.1 1438554 R 391009 CDS YP_001306677.1 150021323 5296606 complement(1439303..1439656) 1 NC_009616.1 hypothetical protein 1439656 5296606 Tmel_1445 Thermosipho melanesiensis BI429 hypothetical protein YP_001306677.1 1439303 R 391009 CDS YP_001306678.1 150021324 5297782 complement(1439689..1442958) 1 NC_009616.1 PFAM: Fibronectin, type III domain protein; fibronectin, type III domain-containing protein 1442958 5297782 Tmel_1446 Thermosipho melanesiensis BI429 fibronectin, type III domain-containing protein YP_001306678.1 1439689 R 391009 CDS YP_001306679.1 150021325 5297783 complement(1443179..1444492) 1 NC_009616.1 hypothetical protein 1444492 5297783 Tmel_1447 Thermosipho melanesiensis BI429 hypothetical protein YP_001306679.1 1443179 R 391009 CDS YP_001306680.1 150021326 5296510 complement(1444595..1444939) 1 NC_009616.1 hypothetical protein 1444939 5296510 Tmel_1448 Thermosipho melanesiensis BI429 hypothetical protein YP_001306680.1 1444595 R 391009 CDS YP_001306681.1 150021327 5296511 complement(1444959..1448321) 1 NC_009616.1 TIGRFAM: phage tail tape measure protein, TP901 family; TP901 family phage tail tape measure protein 1448321 5296511 Tmel_1449 Thermosipho melanesiensis BI429 TP901 family phage tail tape measure protein YP_001306681.1 1444959 R 391009 CDS YP_001306682.1 150021328 5297560 complement(1448327..1448821) 1 NC_009616.1 hypothetical protein 1448821 5297560 Tmel_1450 Thermosipho melanesiensis BI429 hypothetical protein YP_001306682.1 1448327 R 391009 CDS YP_001306683.1 150021329 5297561 complement(1448805..1449170) 1 NC_009616.1 hypothetical protein 1449170 5297561 Tmel_1451 Thermosipho melanesiensis BI429 hypothetical protein YP_001306683.1 1448805 R 391009 CDS YP_001306684.1 150021330 5296935 complement(1449182..1450144) 1 NC_009616.1 hypothetical protein 1450144 5296935 Tmel_1452 Thermosipho melanesiensis BI429 hypothetical protein YP_001306684.1 1449182 R 391009 CDS YP_001306685.1 150021331 5297653 complement(1450159..1450518) 1 NC_009616.1 hypothetical protein 1450518 5297653 Tmel_1453 Thermosipho melanesiensis BI429 hypothetical protein YP_001306685.1 1450159 R 391009 CDS YP_001306686.1 150021332 5297654 complement(1450511..1450981) 1 NC_009616.1 hypothetical protein 1450981 5297654 Tmel_1454 Thermosipho melanesiensis BI429 hypothetical protein YP_001306686.1 1450511 R 391009 CDS YP_001306687.1 150021333 5297688 complement(1450978..1451463) 1 NC_009616.1 hypothetical protein 1451463 5297688 Tmel_1455 Thermosipho melanesiensis BI429 hypothetical protein YP_001306687.1 1450978 R 391009 CDS YP_001306688.1 150021334 5297689 complement(1451477..1451671) 1 NC_009616.1 hypothetical protein 1451671 5297689 Tmel_1456 Thermosipho melanesiensis BI429 hypothetical protein YP_001306688.1 1451477 R 391009 CDS YP_001306689.1 150021335 5296781 complement(1451726..1452814) 1 NC_009616.1 hypothetical protein 1452814 5296781 Tmel_1457 Thermosipho melanesiensis BI429 hypothetical protein YP_001306689.1 1451726 R 391009 CDS YP_001306690.1 150021336 5296782 complement(1452831..1453544) 1 NC_009616.1 hypothetical protein 1453544 5296782 Tmel_1458 Thermosipho melanesiensis BI429 hypothetical protein YP_001306690.1 1452831 R 391009 CDS YP_001306691.1 150021337 5296648 complement(1453561..1453827) 1 NC_009616.1 hypothetical protein 1453827 5296648 Tmel_1459 Thermosipho melanesiensis BI429 hypothetical protein YP_001306691.1 1453561 R 391009 CDS YP_001306692.1 150021338 5296649 complement(1453832..1454557) 1 NC_009616.1 hypothetical protein 1454557 5296649 Tmel_1460 Thermosipho melanesiensis BI429 hypothetical protein YP_001306692.1 1453832 R 391009 CDS YP_001306693.1 150021339 5296625 complement(1454619..1455860) 1 NC_009616.1 hypothetical protein 1455860 5296625 Tmel_1461 Thermosipho melanesiensis BI429 hypothetical protein YP_001306693.1 1454619 R 391009 CDS YP_001306694.1 150021340 5296626 complement(1455871..1457136) 1 NC_009616.1 PFAM: protein of unknown function DUF264; hypothetical protein 1457136 5296626 Tmel_1462 Thermosipho melanesiensis BI429 hypothetical protein YP_001306694.1 1455871 R 391009 CDS YP_001306695.1 150021341 5296621 complement(1457117..1457659) 1 NC_009616.1 hypothetical protein 1457659 5296621 Tmel_1463 Thermosipho melanesiensis BI429 hypothetical protein YP_001306695.1 1457117 R 391009 CDS YP_001306696.1 150021342 5296622 complement(1458338..1458511) 1 NC_009616.1 hypothetical protein 1458511 5296622 Tmel_1464 Thermosipho melanesiensis BI429 hypothetical protein YP_001306696.1 1458338 R 391009 CDS YP_001306697.1 150021343 5297434 1458815..1459381 1 NC_009616.1 PFAM: protein of unknown function DUF88; hypothetical protein 1459381 5297434 Tmel_1465 Thermosipho melanesiensis BI429 hypothetical protein YP_001306697.1 1458815 D 391009 CDS YP_001306698.1 150021344 5297787 complement(1459560..1459754) 1 NC_009616.1 hypothetical protein 1459754 5297787 Tmel_1466 Thermosipho melanesiensis BI429 hypothetical protein YP_001306698.1 1459560 R 391009 CDS YP_001306699.1 150021345 5297788 complement(1460292..1460759) 1 NC_009616.1 ECF subfamily RNA polymerase sigma-24 factor 1460759 5297788 Tmel_1467 Thermosipho melanesiensis BI429 ECF subfamily RNA polymerase sigma-24 factor YP_001306699.1 1460292 R 391009 CDS YP_001306700.1 150021346 5297279 complement(1461153..1461329) 1 NC_009616.1 hypothetical protein 1461329 5297279 Tmel_1468 Thermosipho melanesiensis BI429 hypothetical protein YP_001306700.1 1461153 R 391009 CDS YP_001306701.1 150021347 5297280 complement(1461329..1462081) 1 NC_009616.1 hypothetical protein 1462081 5297280 Tmel_1469 Thermosipho melanesiensis BI429 hypothetical protein YP_001306701.1 1461329 R 391009 CDS YP_001306702.1 150021348 5296595 complement(1462430..1462996) 1 NC_009616.1 hypothetical protein 1462996 5296595 Tmel_1470 Thermosipho melanesiensis BI429 hypothetical protein YP_001306702.1 1462430 R 391009 CDS YP_001306703.1 150021349 5296596 complement(1462989..1463819) 1 NC_009616.1 PFAM: regulatory protein, Crp; CRP/FNR family transcriptional regulator 1463819 5296596 Tmel_1471 Thermosipho melanesiensis BI429 CRP/FNR family transcriptional regulator YP_001306703.1 1462989 R 391009 CDS YP_001306704.1 150021350 5296508 complement(1463883..1464785) 1 NC_009616.1 PFAM: RecT protein; recombination and repair protein RecT 1464785 recT 5296508 recT Thermosipho melanesiensis BI429 recombination and repair protein RecT YP_001306704.1 1463883 R 391009 CDS YP_001306705.1 150021351 5296509 complement(1464797..1465717) 1 NC_009616.1 Phage-like protein endonuclease-like protein 1465717 5296509 Tmel_1473 Thermosipho melanesiensis BI429 Phage-like protein endonuclease-like protein YP_001306705.1 1464797 R 391009 CDS YP_001306706.1 150021352 5297753 complement(1465714..1465995) 1 NC_009616.1 hypothetical protein 1465995 5297753 Tmel_1474 Thermosipho melanesiensis BI429 hypothetical protein YP_001306706.1 1465714 R 391009 CDS YP_001306707.1 150021353 5297754 complement(1466266..1466478) 1 NC_009616.1 hypothetical protein 1466478 5297754 Tmel_1475 Thermosipho melanesiensis BI429 hypothetical protein YP_001306707.1 1466266 R 391009 CDS YP_001306708.1 150021354 5297798 1466559..1467053 1 NC_009616.1 hypothetical protein 1467053 5297798 Tmel_1476 Thermosipho melanesiensis BI429 hypothetical protein YP_001306708.1 1466559 D 391009 CDS YP_001306709.1 150021355 5297799 complement(1467101..1467355) 1 NC_009616.1 hypothetical protein 1467355 5297799 Tmel_1477 Thermosipho melanesiensis BI429 hypothetical protein YP_001306709.1 1467101 R 391009 CDS YP_001306710.1 150021356 5297786 complement(1467379..1467597) 1 NC_009616.1 PFAM: helix-turn-helix domain protein; XRE family transcriptional regulator 1467597 5297786 Tmel_1478 Thermosipho melanesiensis BI429 XRE family transcriptional regulator YP_001306710.1 1467379 R 391009 CDS YP_001306711.1 150021357 5296572 1467855..1468475 1 NC_009616.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; putative prophage repressor 1468475 5296572 Tmel_1479 Thermosipho melanesiensis BI429 putative prophage repressor YP_001306711.1 1467855 D 391009 CDS YP_001306712.1 150021358 5296573 1468486..1469253 1 NC_009616.1 PFAM: DNA methylase N-4/N-6 domain protein; DNA methylase N-4/N-6 domain-containing protein 1469253 5296573 Tmel_1480 Thermosipho melanesiensis BI429 DNA methylase N-4/N-6 domain-containing protein YP_001306712.1 1468486 D 391009 CDS YP_001306713.1 150021359 5296637 1469306..1469983 1 NC_009616.1 Type II site-specific deoxyribonuclease 1469983 5296637 Tmel_1481 Thermosipho melanesiensis BI429 Type II site-specific deoxyribonuclease YP_001306713.1 1469306 D 391009 CDS YP_001306714.1 150021360 5296638 1470057..1470902 1 NC_009616.1 hypothetical protein 1470902 5296638 Tmel_1482 Thermosipho melanesiensis BI429 hypothetical protein YP_001306714.1 1470057 D 391009 CDS YP_001306715.1 150021361 5297583 1470964..1471674 1 NC_009616.1 hypothetical protein 1471674 5297583 Tmel_1483 Thermosipho melanesiensis BI429 hypothetical protein YP_001306715.1 1470964 D 391009 CDS YP_001306716.1 150021362 5297584 1471677..1472192 1 NC_009616.1 hypothetical protein 1472192 5297584 Tmel_1484 Thermosipho melanesiensis BI429 hypothetical protein YP_001306716.1 1471677 D 391009 CDS YP_001306717.1 150021363 5296999 1472204..1472605 1 NC_009616.1 hypothetical protein 1472605 5296999 Tmel_1485 Thermosipho melanesiensis BI429 hypothetical protein YP_001306717.1 1472204 D 391009 CDS YP_001306718.1 150021364 5297000 1472710..1474167 1 NC_009616.1 PFAM: Resolvase, N-terminal domain; Recombinase; resolvase domain-containing protein 1474167 5297000 Tmel_1486 Thermosipho melanesiensis BI429 resolvase domain-containing protein YP_001306718.1 1472710 D 391009 CDS YP_001306719.1 150021365 5297558 complement(1474581..1475312) 1 NC_009616.1 PFAM: protein of unknown function DUF81; hypothetical protein 1475312 5297558 Tmel_1487 Thermosipho melanesiensis BI429 hypothetical protein YP_001306719.1 1474581 R 391009 CDS YP_001306720.1 150021366 5297930 1476399..1477283 1 NC_009616.1 PFAM: PSP1 domain protein; PSP1 domain-containing protein 1477283 5297930 Tmel_1490 Thermosipho melanesiensis BI429 PSP1 domain-containing protein YP_001306720.1 1476399 D 391009 CDS YP_001306721.1 150021367 5297931 1477270..1477410 1 NC_009616.1 hypothetical protein 1477410 5297931 Tmel_1491 Thermosipho melanesiensis BI429 hypothetical protein YP_001306721.1 1477270 D 391009 CDS YP_001306722.1 150021368 5296751 1477415..1477891 1 NC_009616.1 PFAM: protein of unknown function UPF0079; hypothetical protein 1477891 5296751 Tmel_1492 Thermosipho melanesiensis BI429 hypothetical protein YP_001306722.1 1477415 D 391009 CDS YP_001306723.1 150021369 5296644 1477872..1480265 1 NC_009616.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATP-dependent protease La 1480265 5296644 Tmel_1493 Thermosipho melanesiensis BI429 ATP-dependent protease La YP_001306723.1 1477872 D 391009 CDS YP_001306724.1 150021370 5296645 1480240..1480815 1 NC_009616.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1480815 engB 5296645 engB Thermosipho melanesiensis BI429 ribosome biogenesis GTP-binding protein YsxC YP_001306724.1 1480240 D 391009 CDS YP_001306725.1 150021371 5297603 1480812..1482443 1 NC_009616.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1482443 argS 5297603 argS Thermosipho melanesiensis BI429 arginyl-tRNA synthetase YP_001306725.1 1480812 D 391009 CDS YP_001306726.1 150021372 5297604 1482455..1483852 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; histidine kinase 1483852 5297604 Tmel_1496 Thermosipho melanesiensis BI429 histidine kinase YP_001306726.1 1482455 D 391009 CDS YP_001306727.1 150021373 5297142 1483853..1484710 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; Metal-dependent hydrolase HDOD; metal dependent phosphohydrolase 1484710 5297142 Tmel_1497 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306727.1 1483853 D 391009 CDS YP_001306728.1 150021374 5297143 1484700..1485077 1 NC_009616.1 PFAM: ribosome-binding factor A; ribosome-binding factor A 1485077 5297143 Tmel_1498 Thermosipho melanesiensis BI429 ribosome-binding factor A YP_001306728.1 1484700 D 391009 CDS YP_001306729.1 150021375 5297401 1485108..1485449 1 NC_009616.1 PFAM: flagellar protein FlaG protein; flagellar protein FlaG protein 1485449 5297401 Tmel_1499 Thermosipho melanesiensis BI429 flagellar protein FlaG protein YP_001306729.1 1485108 D 391009 CDS YP_001306730.1 150021376 5297402 1485461..1487236 1 NC_009616.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook-associated 2 domain-containing protein 1487236 5297402 Tmel_1500 Thermosipho melanesiensis BI429 flagellar hook-associated 2 domain-containing protein YP_001306730.1 1485461 D 391009 CDS YP_001306731.1 150021377 5296931 complement(1487262..1488311) 1 NC_009616.1 PFAM: von Willebrand factor, type A; von Willebrand factor, type A 1488311 5296931 Tmel_1501 Thermosipho melanesiensis BI429 von Willebrand factor, type A YP_001306731.1 1487262 R 391009 CDS YP_001306732.1 150021378 5296932 complement(1488327..1488815) 1 NC_009616.1 hypothetical protein 1488815 5296932 Tmel_1502 Thermosipho melanesiensis BI429 hypothetical protein YP_001306732.1 1488327 R 391009 CDS YP_001306733.1 150021379 5296501 1489007..1490029 1 NC_009616.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1490029 5296501 Tmel_1503 Thermosipho melanesiensis BI429 ribosomal RNA large subunit methyltransferase N YP_001306733.1 1489007 D 391009 CDS YP_001306734.1 150021380 5296502 1490038..1490499 1 NC_009616.1 PFAM: PASTA domain containing protein; PASTA domain-containing protein 1490499 5296502 Tmel_1504 Thermosipho melanesiensis BI429 PASTA domain-containing protein YP_001306734.1 1490038 D 391009 CDS YP_001306735.1 150021381 5297089 1490496..1491362 1 NC_009616.1 TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; ribosome small subunit-dependent GTPase A 1491362 5297089 Tmel_1505 Thermosipho melanesiensis BI429 ribosome small subunit-dependent GTPase A YP_001306735.1 1490496 D 391009 CDS YP_001306736.1 150021382 5297323 1491362..1493026 1 NC_009616.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1493026 5297323 Tmel_1506 Thermosipho melanesiensis BI429 radical SAM domain-containing protein YP_001306736.1 1491362 D 391009 CDS YP_001306737.1 150021383 5297324 1493050..1494342 1 NC_009616.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; hypothetical protein 1494342 5297324 Tmel_1507 Thermosipho melanesiensis BI429 hypothetical protein YP_001306737.1 1493050 D 391009 CDS YP_001306738.1 150021384 5296663 1494335..1494724 1 NC_009616.1 TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; cytidine deaminase 1494724 5296663 Tmel_1508 Thermosipho melanesiensis BI429 cytidine deaminase YP_001306738.1 1494335 D 391009 CDS YP_001306739.1 150021385 5296664 1494721..1496244 1 NC_009616.1 PFAM: SMC domain protein; SMC domain-containing protein 1496244 5296664 Tmel_1509 Thermosipho melanesiensis BI429 SMC domain-containing protein YP_001306739.1 1494721 D 391009 CDS YP_001306740.1 150021386 5296746 1496249..1496761 1 NC_009616.1 hypothetical protein 1496761 5296746 Tmel_1510 Thermosipho melanesiensis BI429 hypothetical protein YP_001306740.1 1496249 D 391009 CDS YP_001306741.1 150021387 5296747 complement(1496741..1498729) 1 NC_009616.1 TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like; NAD-dependent DNA ligase 1498729 5296747 Tmel_1511 Thermosipho melanesiensis BI429 NAD-dependent DNA ligase YP_001306741.1 1496741 R 391009 CDS YP_001306742.1 150021388 5296680 1498827..1499045 1 NC_009616.1 hypothetical protein 1499045 5296680 Tmel_1512 Thermosipho melanesiensis BI429 hypothetical protein YP_001306742.1 1498827 D 391009 CDS YP_001306743.1 150021389 5296681 complement(1499049..1501163) 1 NC_009616.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; ribonuclease R 1501163 5296681 Tmel_1513 Thermosipho melanesiensis BI429 ribonuclease R YP_001306743.1 1499049 R 391009 CDS YP_001306744.1 150021390 5296869 complement(1501168..1502418) 1 NC_009616.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; NusB/RsmB/TIM44 1502418 5296869 Tmel_1514 Thermosipho melanesiensis BI429 NusB/RsmB/TIM44 YP_001306744.1 1501168 R 391009 CDS YP_001306745.1 150021391 5296870 complement(1502415..1503107) 1 NC_009616.1 PFAM: peptidase, membrane zinc metallopeptidase, putative; peptidase, membrane zinc metallopeptidase 1503107 5296870 Tmel_1515 Thermosipho melanesiensis BI429 peptidase, membrane zinc metallopeptidase YP_001306745.1 1502415 R 391009 CDS YP_001306746.1 150021392 5296988 complement(1503114..1503770) 1 NC_009616.1 PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator 1503770 5296988 Tmel_1516 Thermosipho melanesiensis BI429 two component transcriptional regulator YP_001306746.1 1503114 R 391009 CDS YP_001306747.1 150021393 5296989 complement(1503751..1504467) 1 NC_009616.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; RNA methyltransferase 1504467 5296989 Tmel_1517 Thermosipho melanesiensis BI429 RNA methyltransferase YP_001306747.1 1503751 R 391009 CDS YP_001306748.1 150021394 5296696 complement(1504464..1505219) 1 NC_009616.1 TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; MazG family protein 1505219 5296696 Tmel_1518 Thermosipho melanesiensis BI429 MazG family protein YP_001306748.1 1504464 R 391009 CDS YP_001306749.1 150021395 5297399 complement(1505183..1506178) 1 NC_009616.1 PFAM: protein of unknown function UPF0118; hypothetical protein 1506178 5297399 Tmel_1519 Thermosipho melanesiensis BI429 hypothetical protein YP_001306749.1 1505183 R 391009 CDS YP_001306750.1 150021396 5297400 complement(1506168..1507382) 1 NC_009616.1 hypothetical protein 1507382 5297400 Tmel_1520 Thermosipho melanesiensis BI429 hypothetical protein YP_001306750.1 1506168 R 391009 CDS YP_001306751.1 150021397 5296979 1507462..1508643 1 NC_009616.1 hypothetical protein 1508643 5296979 Tmel_1521 Thermosipho melanesiensis BI429 hypothetical protein YP_001306751.1 1507462 D 391009 CDS YP_001306752.1 150021398 5296980 complement(1508694..1510703) 1 NC_009616.1 RND efflux transporter 1510703 5296980 Tmel_1522 Thermosipho melanesiensis BI429 RND efflux transporter YP_001306752.1 1508694 R 391009 CDS YP_001306753.1 150021399 5296816 complement(1510700..1511134) 1 NC_009616.1 hypothetical protein 1511134 5296816 Tmel_1523 Thermosipho melanesiensis BI429 hypothetical protein YP_001306753.1 1510700 R 391009 CDS YP_001306754.1 150021400 5296817 complement(1511124..1513595) 1 NC_009616.1 PFAM: DNA polymerase III, alpha subunit; DNA-directed DNA polymerase 1513595 5296817 Tmel_1524 Thermosipho melanesiensis BI429 DNA-directed DNA polymerase YP_001306754.1 1511124 R 391009 CDS YP_001306755.1 150021401 5296754 complement(1513592..1514236) 1 NC_009616.1 PFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 1514236 5296754 Tmel_1525 Thermosipho melanesiensis BI429 ribulose-phosphate 3-epimerase YP_001306755.1 1513592 R 391009 CDS YP_001306756.1 150021402 5296755 1514294..1515091 1 NC_009616.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1515091 5296755 Tmel_1526 Thermosipho melanesiensis BI429 purine nucleoside phosphorylase YP_001306756.1 1514294 D 391009 CDS YP_001306757.1 150021403 5296818 1515095..1516075 1 NC_009616.1 PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; phosphoesterase domain-containing protein 1516075 5296818 Tmel_1527 Thermosipho melanesiensis BI429 phosphoesterase domain-containing protein YP_001306757.1 1515095 D 391009 CDS YP_001306758.1 150021404 5296819 1516099..1520118 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 1520118 5296819 Tmel_1528 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001306758.1 1516099 D 391009 CDS YP_001306759.1 150021405 5296994 1520105..1520983 1 NC_009616.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1520983 5296994 Tmel_1529 Thermosipho melanesiensis BI429 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001306759.1 1520105 D 391009 CDS YP_001306760.1 150021406 5297819 1520996..1522336 1 NC_009616.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 1 1522336 5297819 Tmel_1530 Thermosipho melanesiensis BI429 putative aminopeptidase 1 YP_001306760.1 1520996 D 391009 CDS YP_001306761.1 150021407 5297820 1522341..1522766 1 NC_009616.1 PFAM: regulatory protein, MarR; transcriptional regulator TrmB; transcriptional regulator TrmB 1522766 5297820 Tmel_1531 Thermosipho melanesiensis BI429 transcriptional regulator TrmB YP_001306761.1 1522341 D 391009 CDS YP_001306762.1 150021408 5296528 1522769..1524142 1 NC_009616.1 PFAM: PEGA domain protein; PEGA domain-containing protein 1524142 5296528 Tmel_1532 Thermosipho melanesiensis BI429 PEGA domain-containing protein YP_001306762.1 1522769 D 391009 CDS YP_001306763.1 150021409 5296529 1524143..1525441 1 NC_009616.1 hypothetical protein 1525441 5296529 Tmel_1533 Thermosipho melanesiensis BI429 hypothetical protein YP_001306763.1 1524143 D 391009 CDS YP_001306764.1 150021410 5297901 1525453..1526823 1 NC_009616.1 PFAM: protein of unknown function DUF342; hypothetical protein 1526823 5297901 Tmel_1534 Thermosipho melanesiensis BI429 hypothetical protein YP_001306764.1 1525453 D 391009 CDS YP_001306765.1 150021411 5297902 1526820..1527608 1 NC_009616.1 PFAM: mannose-6-phosphate isomerase, type I; mannose-6-phosphate isomerase, type I 1527608 5297902 Tmel_1535 Thermosipho melanesiensis BI429 mannose-6-phosphate isomerase, type I YP_001306765.1 1526820 D 391009 CDS YP_001306766.1 150021412 5296810 complement(1527574..1528458) 1 NC_009616.1 PFAM: protein of unknown function DUF89; hypothetical protein 1528458 5296810 Tmel_1536 Thermosipho melanesiensis BI429 hypothetical protein YP_001306766.1 1527574 R 391009 CDS YP_001306767.1 150021413 5297857 complement(1528460..1528714) 1 NC_009616.1 PFAM: phosphopantetheine-binding; phosphopantetheine-binding 1528714 5297857 Tmel_1537 Thermosipho melanesiensis BI429 phosphopantetheine-binding YP_001306767.1 1528460 R 391009 CDS YP_001306768.1 150021414 5297858 1528913..1529854 1 NC_009616.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1529854 ruvB 5297858 ruvB Thermosipho melanesiensis BI429 Holliday junction DNA helicase RuvB YP_001306768.1 1528913 D 391009 CDS YP_001306769.1 150021415 5296852 1529844..1530530 1 NC_009616.1 PFAM: alanine racemase domain protein; alanine racemase domain-containing protein 1530530 5296852 Tmel_1539 Thermosipho melanesiensis BI429 alanine racemase domain-containing protein YP_001306769.1 1529844 D 391009 CDS YP_001306770.1 150021416 5296853 1530535..1530825 1 NC_009616.1 PFAM: protein of unknown function YGGT; hypothetical protein 1530825 5296853 Tmel_1540 Thermosipho melanesiensis BI429 hypothetical protein YP_001306770.1 1530535 D 391009 CDS YP_001306771.1 150021417 5297193 1530822..1531577 1 NC_009616.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1531577 pnk 5297193 pnk Thermosipho melanesiensis BI429 inorganic polyphosphate/ATP-NAD kinase YP_001306771.1 1530822 D 391009 CDS YP_001306772.1 150021418 5297194 1531593..1532294 1 NC_009616.1 PFAM: PhoU family protein; phosphate uptake regulator PhoU 1532294 5297194 Tmel_1542 Thermosipho melanesiensis BI429 phosphate uptake regulator PhoU YP_001306772.1 1531593 D 391009 CDS YP_001306773.1 150021419 5297489 1532291..1535581 1 NC_009616.1 PFAM: permease YjgP/YjgQ family protein; permease YjgP/YjgQ family protein 1535581 5297489 Tmel_1543 Thermosipho melanesiensis BI429 permease YjgP/YjgQ family protein YP_001306773.1 1532291 D 391009 CDS YP_001306774.1 150021420 5297393 1535597..1536904 1 NC_009616.1 TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; protein of unknown function Met10; (Uracil-5)-methyltransferase; RNA methyltransferase 1536904 5297393 Tmel_1544 Thermosipho melanesiensis BI429 RNA methyltransferase YP_001306774.1 1535597 D 391009 CDS YP_001306775.1 150021421 5297394 1536940..1537539 1 NC_009616.1 PFAM: MGS domain protein; IMP cyclohydrolase 1537539 5297394 Tmel_1545 Thermosipho melanesiensis BI429 IMP cyclohydrolase YP_001306775.1 1536940 D 391009 CDS YP_001306776.1 150021422 5296875 1537549..1538148 1 NC_009616.1 hypothetical protein 1538148 5296875 Tmel_1546 Thermosipho melanesiensis BI429 hypothetical protein YP_001306776.1 1537549 D 391009 CDS YP_001306777.1 150021423 5296876 1538132..1538401 1 NC_009616.1 flagellar protein FhlB-like protein 1538401 5296876 Tmel_1547 Thermosipho melanesiensis BI429 flagellar protein FhlB-like protein YP_001306777.1 1538132 D 391009 CDS YP_001306778.1 150021424 5296737 1538403..1539305 1 NC_009616.1 hypothetical protein 1539305 5296737 Tmel_1548 Thermosipho melanesiensis BI429 hypothetical protein YP_001306778.1 1538403 D 391009 CDS YP_001306779.1 150021425 5296738 1539324..1540433 1 NC_009616.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1540433 prfB 5296738 prfB Thermosipho melanesiensis BI429 peptide chain release factor 2 YP_001306779.1 1539324 D 391009 CDS YP_001306780.1 150021426 5296849 1540444..1541247 1 NC_009616.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; septum site-determining protein MinD 1541247 5296849 Tmel_1550 Thermosipho melanesiensis BI429 septum site-determining protein MinD YP_001306780.1 1540444 D 391009 CDS YP_001306781.1 150021427 5297624 1541253..1541519 1 NC_009616.1 hypothetical protein 1541519 5297624 Tmel_1551 Thermosipho melanesiensis BI429 hypothetical protein YP_001306781.1 1541253 D 391009 CDS YP_001306782.1 150021428 5297625 1541540..1542133 1 NC_009616.1 hypothetical protein 1542133 5297625 Tmel_1552 Thermosipho melanesiensis BI429 hypothetical protein YP_001306782.1 1541540 D 391009 CDS YP_001306783.1 150021429 5296611 1542145..1542369 1 NC_009616.1 hypothetical protein 1542369 5296611 Tmel_1553 Thermosipho melanesiensis BI429 hypothetical protein YP_001306783.1 1542145 D 391009 CDS YP_001306784.1 150021430 5296612 1542366..1543148 1 NC_009616.1 hypothetical protein 1543148 5296612 Tmel_1554 Thermosipho melanesiensis BI429 hypothetical protein YP_001306784.1 1542366 D 391009 CDS YP_001306785.1 150021431 5296639 1543150..1544037 1 NC_009616.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase; signal recognition particle-docking protein FtsY 1544037 5296639 Tmel_1555 Thermosipho melanesiensis BI429 signal recognition particle-docking protein FtsY YP_001306785.1 1543150 D 391009 CDS YP_001306786.1 150021432 5296640 1544039..1544707 1 NC_009616.1 hypothetical protein 1544707 5296640 Tmel_1556 Thermosipho melanesiensis BI429 hypothetical protein YP_001306786.1 1544039 D 391009 CDS YP_001306787.1 150021433 5296894 1544713..1546266 1 NC_009616.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; 3D domain protein; peptidoglycan-binding LysM 1546266 5296894 Tmel_1557 Thermosipho melanesiensis BI429 peptidoglycan-binding LysM YP_001306787.1 1544713 D 391009 CDS YP_001306788.1 150021434 5297080 1546269..1546715 1 NC_009616.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; BadM/Rrf2 family transcriptional regulator 1546715 5297080 Tmel_1558 Thermosipho melanesiensis BI429 BadM/Rrf2 family transcriptional regulator YP_001306788.1 1546269 D 391009 CDS YP_001306789.1 150021435 5297081 1546769..1547788 1 NC_009616.1 PFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1547788 5297081 Tmel_1559 Thermosipho melanesiensis BI429 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_001306789.1 1546769 D 391009 CDS YP_001306790.1 150021436 5296692 1547766..1548278 1 NC_009616.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 1548278 5296692 Tmel_1560 Thermosipho melanesiensis BI429 hypoxanthine phosphoribosyltransferase YP_001306790.1 1547766 D 391009 CDS YP_001306791.1 150021437 5296693 1548275..1549438 1 NC_009616.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; cell envelope-related transcriptional attenuator 1549438 5296693 Tmel_1561 Thermosipho melanesiensis BI429 cell envelope-related transcriptional attenuator YP_001306791.1 1548275 D 391009 CDS YP_001306792.1 150021438 5297015 complement(1549419..1550099) 1 NC_009616.1 PFAM: Endonuclease V; deoxyribonuclease V 1550099 5297015 Tmel_1562 Thermosipho melanesiensis BI429 deoxyribonuclease V YP_001306792.1 1549419 R 391009 CDS YP_001306793.1 150021439 5297016 complement(1550101..1550808) 1 NC_009616.1 hypothetical protein 1550808 5297016 Tmel_1563 Thermosipho melanesiensis BI429 hypothetical protein YP_001306793.1 1550101 R 391009 CDS YP_001306794.1 150021440 5297553 complement(1551518..1552420) 1 NC_009616.1 TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; putative radical SAM protein 1552420 5297553 Tmel_1565 Thermosipho melanesiensis BI429 putative radical SAM protein YP_001306794.1 1551518 R 391009 CDS YP_001306795.1 150021441 5297934 complement(1552417..1553652) 1 NC_009616.1 PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase 1553652 5297934 Tmel_1566 Thermosipho melanesiensis BI429 amidohydrolase YP_001306795.1 1552417 R 391009 CDS YP_001306796.1 150021442 5297935 complement(1553649..1553987) 1 NC_009616.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; iojap-like protein 1553987 5297935 Tmel_1567 Thermosipho melanesiensis BI429 iojap-like protein YP_001306796.1 1553649 R 391009 CDS YP_001306797.1 150021443 5297651 complement(1553993..1555291) 1 NC_009616.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; FolC bifunctional protein 1555291 5297651 Tmel_1568 Thermosipho melanesiensis BI429 FolC bifunctional protein YP_001306797.1 1553993 R 391009 CDS YP_001306798.1 150021444 5297652 complement(1555301..1557901) 1 NC_009616.1 TIGRFAM: valyl-tRNA synthetase; valyl-tRNA synthetase 1557901 5297652 Tmel_1569 Thermosipho melanesiensis BI429 valyl-tRNA synthetase YP_001306798.1 1555301 R 391009 CDS YP_001306799.1 150021445 5296590 complement(1557894..1558310) 1 NC_009616.1 putative diguanylate cyclase 1558310 5296590 Tmel_1570 Thermosipho melanesiensis BI429 putative diguanylate cyclase YP_001306799.1 1557894 R 391009 CDS YP_001306800.1 150021446 5296591 1558428..1559744 1 NC_009616.1 TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; RnfABCDGE type electron transport complex subunit C 1559744 5296591 Tmel_1571 Thermosipho melanesiensis BI429 RnfABCDGE type electron transport complex subunit C YP_001306800.1 1558428 D 391009 CDS YP_001306801.1 150021447 5296641 1559744..1560700 1 NC_009616.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; RnfABCDGE type electron transport complex subunit D 1560700 5296641 Tmel_1572 Thermosipho melanesiensis BI429 RnfABCDGE type electron transport complex subunit D YP_001306801.1 1559744 D 391009 CDS YP_001306802.1 150021448 5296769 1560697..1561374 1 NC_009616.1 TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; RnfABCDGE type electron transport complex subunit G 1561374 5296769 Tmel_1573 Thermosipho melanesiensis BI429 RnfABCDGE type electron transport complex subunit G YP_001306802.1 1560697 D 391009 CDS YP_001306803.1 150021449 5296770 1561364..1561978 1 NC_009616.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1561978 5296770 Tmel_1574 Thermosipho melanesiensis BI429 electron transport complex RsxE subunit YP_001306803.1 1561364 D 391009 CDS YP_001306804.1 150021450 5297482 1561975..1562550 1 NC_009616.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; RnfABCDGE type electron transport complex subunit A 1562550 5297482 Tmel_1575 Thermosipho melanesiensis BI429 RnfABCDGE type electron transport complex subunit A YP_001306804.1 1561975 D 391009 CDS YP_001306805.1 150021451 5296670 1562719..1563987 1 NC_009616.1 PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter 1563987 5296670 Tmel_1576 Thermosipho melanesiensis BI429 citrate transporter YP_001306805.1 1562719 D 391009 CDS YP_001306806.1 150021452 5297191 1563999..1564934 1 NC_009616.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; CaCA family Na(+)/Ca(+) antiporter 1564934 5297191 Tmel_1577 Thermosipho melanesiensis BI429 CaCA family Na(+)/Ca(+) antiporter YP_001306806.1 1563999 D 391009 CDS YP_001306807.1 150021453 5297192 1564947..1566398 1 NC_009616.1 TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase; inosine-5'-monophosphate dehydrogenase 1566398 5297192 Tmel_1578 Thermosipho melanesiensis BI429 inosine-5'-monophosphate dehydrogenase YP_001306807.1 1564947 D 391009 CDS YP_001306808.1 150021454 5297413 1566654..1568351 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; methyl-accepting chemotaxis sensory transducer 1568351 5297413 Tmel_1579 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001306808.1 1566654 D 391009 CDS YP_001306809.1 150021455 5297507 1568430..1569857 1 NC_009616.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 1569857 5297507 Tmel_1580 Thermosipho melanesiensis BI429 alpha amylase catalytic subunit YP_001306809.1 1568430 D 391009 CDS YP_001306810.1 150021456 5297508 1569872..1570570 1 NC_009616.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; type 11 methyltransferase 1570570 5297508 Tmel_1581 Thermosipho melanesiensis BI429 type 11 methyltransferase YP_001306810.1 1569872 D 391009 CDS YP_001306811.1 150021457 5297226 1570640..1571374 1 NC_009616.1 catalyzes the formation of L-aspartate to iminoaspartate in NAD(+) biosynthesis; L-aspartate dehydrogenase 1571374 5297226 Tmel_1582 Thermosipho melanesiensis BI429 L-aspartate dehydrogenase YP_001306811.1 1570640 D 391009 CDS YP_001306812.1 150021458 5297227 1571379..1572290 1 NC_009616.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1572290 5297227 Tmel_1583 Thermosipho melanesiensis BI429 quinolinate synthetase YP_001306812.1 1571379 D 391009 CDS YP_001306813.1 150021459 5296861 1572292..1573104 1 NC_009616.1 TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; nicotinate-nucleotide pyrophosphorylase 1573104 5296861 Tmel_1584 Thermosipho melanesiensis BI429 nicotinate-nucleotide pyrophosphorylase YP_001306813.1 1572292 D 391009 CDS YP_001306814.1 150021460 5296862 1573288..1574511 1 NC_009616.1 PFAM: Beta-ketoacyl synthase-like; beta-ketoacyl synthase-like protein 1574511 5296862 Tmel_1585 Thermosipho melanesiensis BI429 beta-ketoacyl synthase-like protein YP_001306814.1 1573288 D 391009 CDS YP_001306815.1 150021461 5297548 1574514..1574921 1 NC_009616.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ 1574921 5297548 Tmel_1586 Thermosipho melanesiensis BI429 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001306815.1 1574514 D 391009 CDS YP_001306816.1 150021462 5296958 1574926..1575855 1 NC_009616.1 PFAM: 2-nitropropane dioxygenase, NPD; 2-nitropropane dioxygenase 1575855 5296958 Tmel_1587 Thermosipho melanesiensis BI429 2-nitropropane dioxygenase YP_001306816.1 1574926 D 391009 CDS YP_001306817.1 150021463 5296959 1575855..1576358 1 NC_009616.1 PFAM: BioY protein; BioY protein 1576358 5296959 Tmel_1588 Thermosipho melanesiensis BI429 BioY protein YP_001306817.1 1575855 D 391009 CDS YP_001306818.1 150021464 5296845 1576355..1577245 1 NC_009616.1 PFAM: Acyl transferase; Acyl transferase 1577245 5296845 Tmel_1589 Thermosipho melanesiensis BI429 Acyl transferase YP_001306818.1 1576355 D 391009 CDS YP_001306819.1 150021465 5296846 1577513..1578289 1 NC_009616.1 in Methanocaldococcus jannaschii this enzyme is involved in conversion of 5-phospho-D-ribose-1-pyrophosphate to ribulose-1,5-bisphosphate using NAD as a cofactor; part of RubisCO pathway; ribulose-1,5-biphosphate synthetase 1578289 5296846 Tmel_1590 Thermosipho melanesiensis BI429 ribulose-1,5-biphosphate synthetase YP_001306819.1 1577513 D 391009 CDS YP_001306820.1 150021466 5297289 1578409..1578834 1 NC_009616.1 hypothetical protein 1578834 5297289 Tmel_1591 Thermosipho melanesiensis BI429 hypothetical protein YP_001306820.1 1578409 D 391009 CDS YP_001306821.1 150021467 5297290 1579059..1580336 1 NC_009616.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 1580336 5297290 Tmel_1592 Thermosipho melanesiensis BI429 thiamine biosynthesis protein ThiC YP_001306821.1 1579059 D 391009 CDS YP_001306822.1 150021468 5297922 1580333..1581049 1 NC_009616.1 PFAM: Xylose isomerase domain protein TIM barrel; xylose isomerase domain-containing protein 1581049 5297922 Tmel_1593 Thermosipho melanesiensis BI429 xylose isomerase domain-containing protein YP_001306822.1 1580333 D 391009 CDS YP_001306823.1 150021469 5296760 1581049..1582248 1 NC_009616.1 PFAM: Phosphomethylpyrimidine kinase type-1; phosphomethylpyrimidine kinase type-1 1582248 5296760 Tmel_1594 Thermosipho melanesiensis BI429 phosphomethylpyrimidine kinase type-1 YP_001306823.1 1581049 D 391009 CDS YP_001306824.1 150021470 5296761 1582349..1583308 1 NC_009616.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1583308 5296761 Tmel_1595 Thermosipho melanesiensis BI429 6-phosphofructokinase YP_001306824.1 1582349 D 391009 CDS YP_001306825.1 150021471 5297541 1583305..1584615 1 NC_009616.1 PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase 3 1584615 5297541 Tmel_1596 Thermosipho melanesiensis BI429 amidohydrolase 3 YP_001306825.1 1583305 D 391009 CDS YP_001306826.1 150021472 5297542 complement(1584588..1585613) 1 NC_009616.1 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1585613 5297542 Tmel_1597 Thermosipho melanesiensis BI429 biotin synthase YP_001306826.1 1584588 R 391009 CDS YP_001306827.1 150021473 5297878 complement(1585579..1585848) 1 NC_009616.1 hypothetical protein 1585848 5297878 Tmel_1598 Thermosipho melanesiensis BI429 hypothetical protein YP_001306827.1 1585579 R 391009 CDS YP_001306828.1 150021474 5297879 complement(1585835..1587250) 1 NC_009616.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain; thiamine biosynthesis protein ThiH 1587250 thiH 5297879 thiH Thermosipho melanesiensis BI429 thiamine biosynthesis protein ThiH YP_001306828.1 1585835 R 391009 CDS YP_001306829.1 150021475 5296970 complement(1587252..1587503) 1 NC_009616.1 hypothetical protein 1587503 5296970 Tmel_1600 Thermosipho melanesiensis BI429 hypothetical protein YP_001306829.1 1587252 R 391009 CDS YP_001306830.1 150021476 5297734 complement(1587637..1589385) 1 NC_009616.1 TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; hydrogenase, Fe-only 1589385 5297734 Tmel_1601 Thermosipho melanesiensis BI429 hydrogenase, Fe-only YP_001306830.1 1587637 R 391009 CDS YP_001306831.1 150021477 5297735 complement(1589567..1590448) 1 NC_009616.1 PFAM: Auxin Efflux Carrier; auxin efflux carrier 1590448 5297735 Tmel_1602 Thermosipho melanesiensis BI429 auxin efflux carrier YP_001306831.1 1589567 R 391009 CDS YP_001306832.1 150021478 5297266 complement(1590445..1590693) 1 NC_009616.1 hypothetical protein 1590693 5297266 Tmel_1603 Thermosipho melanesiensis BI429 hypothetical protein YP_001306832.1 1590445 R 391009 CDS YP_001306833.1 150021479 5297267 complement(1590683..1591378) 1 NC_009616.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein; ribonuclease III 1591378 5297267 Tmel_1604 Thermosipho melanesiensis BI429 ribonuclease III YP_001306833.1 1590683 R 391009 CDS YP_001306834.1 150021480 5297099 complement(1591297..1592325) 1 NC_009616.1 PFAM: ExsB family protein; ExsB family protein 1592325 5297099 Tmel_1605 Thermosipho melanesiensis BI429 ExsB family protein YP_001306834.1 1591297 R 391009 CDS YP_001306835.1 150021481 5297100 complement(1592327..1593010) 1 NC_009616.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin--acetyl-CoA-carboxylase ligase 1593010 5297100 Tmel_1606 Thermosipho melanesiensis BI429 biotin--acetyl-CoA-carboxylase ligase YP_001306835.1 1592327 R 391009 CDS YP_001306836.1 150021482 5296820 complement(1592994..1594403) 1 NC_009616.1 TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; integral membrane protein MviN 1594403 5296820 Tmel_1607 Thermosipho melanesiensis BI429 integral membrane protein MviN YP_001306836.1 1592994 R 391009 CDS YP_001306837.1 150021483 5297589 1594512..1594790 1 NC_009616.1 PFAM: Fe-S cluster domain protein; Fe-S cluster domain-containing protein 1594790 5297589 Tmel_1608 Thermosipho melanesiensis BI429 Fe-S cluster domain-containing protein YP_001306837.1 1594512 D 391009 CDS YP_001306838.1 150021484 5297590 1594796..1595590 1 NC_009616.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; DNA protecting protein DprA 1595590 5297590 Tmel_1609 Thermosipho melanesiensis BI429 DNA protecting protein DprA YP_001306838.1 1594796 D 391009 CDS YP_001306839.1 150021485 5297188 1595568..1596410 1 NC_009616.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 1596410 panC 5297188 panC Thermosipho melanesiensis BI429 pantoate--beta-alanine ligase YP_001306839.1 1595568 D 391009 CDS YP_001306840.1 150021486 5297189 1596417..1598525 1 NC_009616.1 PFAM: glycoside hydrolase, family 31; Alpha-glucosidase 1598525 5297189 Tmel_1611 Thermosipho melanesiensis BI429 Alpha-glucosidase YP_001306840.1 1596417 D 391009 CDS YP_001306841.1 150021487 5296783 1598537..1600636 1 NC_009616.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein; polynucleotide phosphorylase/polyadenylase 1600636 5296783 Tmel_1612 Thermosipho melanesiensis BI429 polynucleotide phosphorylase/polyadenylase YP_001306841.1 1598537 D 391009 CDS YP_001306842.1 150021488 5296784 1600633..1601883 1 NC_009616.1 PFAM: peptidase M16 domain protein; peptidase M16 domain-containing protein 1601883 5296784 Tmel_1613 Thermosipho melanesiensis BI429 peptidase M16 domain-containing protein YP_001306842.1 1600633 D 391009 CDS YP_001306843.1 150021489 5297909 1601880..1602875 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1602875 5297909 Tmel_1614 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306843.1 1601880 D 391009 CDS YP_001306844.1 150021490 5297467 1602868..1604265 1 NC_009616.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1604265 hslU 5297467 hslU Thermosipho melanesiensis BI429 ATP-dependent protease ATP-binding subunit HslU YP_001306844.1 1602868 D 391009 CDS YP_001306845.1 150021491 5297468 1604276..1605565 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1605565 5297468 Tmel_1616 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306845.1 1604276 D 391009 CDS YP_001306846.1 150021492 5297895 1605577..1607088 1 NC_009616.1 hypothetical protein 1607088 5297895 Tmel_1617 Thermosipho melanesiensis BI429 hypothetical protein YP_001306846.1 1605577 D 391009 CDS YP_001306847.1 150021493 5297896 1607131..1607727 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1607727 5297896 Tmel_1618 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306847.1 1607131 D 391009 CDS YP_001306848.1 150021494 5297082 1607746..1608396 1 NC_009616.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1608396 5297082 Tmel_1619 Thermosipho melanesiensis BI429 putative translaldolase YP_001306848.1 1607746 D 391009 CDS YP_001306849.1 150021495 5297083 1608402..1610147 1 NC_009616.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1610147 aspS 5297083 aspS Thermosipho melanesiensis BI429 aspartyl-tRNA synthetase YP_001306849.1 1608402 D 391009 CDS YP_001306850.1 150021496 5297630 1610128..1610460 1 NC_009616.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist 1610460 5297630 Tmel_1621 Thermosipho melanesiensis BI429 anti-sigma-factor antagonist YP_001306850.1 1610128 D 391009 CDS YP_001306851.1 150021497 5296824 1610469..1611122 1 NC_009616.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1611122 cmk 5296824 cmk Thermosipho melanesiensis BI429 cytidylate kinase YP_001306851.1 1610469 D 391009 CDS YP_001306852.1 150021498 5296825 1611110..1613542 1 NC_009616.1 these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain-containing protein 1613542 5296825 Tmel_1623 Thermosipho melanesiensis BI429 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain-containing protein YP_001306852.1 1611110 D 391009 CDS YP_001306853.1 150021499 5297716 1613511..1614824 1 NC_009616.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1614824 engA 5297716 engA Thermosipho melanesiensis BI429 GTP-binding protein EngA YP_001306853.1 1613511 D 391009 CDS YP_001306854.1 150021500 5297717 1614839..1615900 1 NC_009616.1 PFAM: basic membrane lipoprotein; basic membrane lipoprotein 1615900 5297717 Tmel_1625 Thermosipho melanesiensis BI429 basic membrane lipoprotein YP_001306854.1 1614839 D 391009 CDS YP_001306855.1 150021501 5297755 1615913..1616839 1 NC_009616.1 hypothetical protein 1616839 5297755 Tmel_1626 Thermosipho melanesiensis BI429 hypothetical protein YP_001306855.1 1615913 D 391009 CDS YP_001306856.1 150021502 5297756 1616841..1618253 1 NC_009616.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1618253 5297756 Tmel_1627 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306856.1 1616841 D 391009 CDS YP_001306857.1 150021503 5297241 1618314..1618448 1 NC_009616.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1618448 rpmH 5297241 rpmH Thermosipho melanesiensis BI429 50S ribosomal protein L34 YP_001306857.1 1618314 D 391009 CDS YP_001306858.1 150021504 5297966 1618430..1618825 1 NC_009616.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein; ribonuclease P protein component 1618825 5297966 Tmel_1629 Thermosipho melanesiensis BI429 ribonuclease P protein component YP_001306858.1 1618430 D 391009 CDS YP_001306859.1 150021505 5297967 1618797..1619042 1 NC_009616.1 PFAM: protein of unknown function DUF37; hypothetical protein 1619042 5297967 Tmel_1630 Thermosipho melanesiensis BI429 hypothetical protein YP_001306859.1 1618797 D 391009 CDS YP_001306860.1 150021506 5298228 1619039..1620340 1 NC_009616.1 PFAM: 60 kDa inner membrane insertion protein; 60 kDa inner membrane insertion protein 1620340 5298228 Tmel_1631 Thermosipho melanesiensis BI429 60 kDa inner membrane insertion protein YP_001306860.1 1619039 D 391009 CDS YP_001306861.1 150021507 5298229 1620346..1621017 1 NC_009616.1 PFAM: single-stranded nucleic acid binding R3H domain protein; single-stranded nucleic acid binding R3H domain-containing protein 1621017 5298229 Tmel_1632 Thermosipho melanesiensis BI429 single-stranded nucleic acid binding R3H domain-containing protein YP_001306861.1 1620346 D 391009 CDS YP_001306862.1 150021508 5298209 1620971..1621312 1 NC_009616.1 PFAM: Cupin 2, conserved barrel domain protein; cupin 2 domain-containing protein 1621312 5298209 Tmel_1633 Thermosipho melanesiensis BI429 cupin 2 domain-containing protein YP_001306862.1 1620971 D 391009 CDS YP_001306863.1 150021509 5298210 1621305..1622324 1 NC_009616.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; Ion transport 2 domain protein; TrkA domain-containing protein 1622324 5298210 Tmel_1634 Thermosipho melanesiensis BI429 TrkA domain-containing protein YP_001306863.1 1621305 D 391009 CDS YP_001306864.1 150021510 5297964 1622497..1623867 1 NC_009616.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; glutamine synthetase, type I 1623867 5297964 Tmel_1635 Thermosipho melanesiensis BI429 glutamine synthetase, type I YP_001306864.1 1622497 D 391009 CDS YP_001306865.1 150021511 5297923 1623967..1625364 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; response regulator receiver modulated diguanylate cyclase 1625364 5297923 Tmel_1636 Thermosipho melanesiensis BI429 response regulator receiver modulated diguanylate cyclase YP_001306865.1 1623967 D 391009 CDS YP_001306866.1 150021512 5297924 1625361..1626413 1 NC_009616.1 PFAM: Endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 1626413 5297924 Tmel_1637 Thermosipho melanesiensis BI429 endonuclease/exonuclease/phosphatase YP_001306866.1 1625361 D 391009 CDS YP_001306867.1 150021513 5297912 1626423..1627742 1 NC_009616.1 PFAM: glycoside hydrolase, family 1; beta-glucosidase 1627742 5297912 Tmel_1638 Thermosipho melanesiensis BI429 beta-glucosidase YP_001306867.1 1626423 D 391009 CDS YP_001306868.1 150021514 5297913 complement(1627739..1628194) 1 NC_009616.1 hypothetical protein 1628194 5297913 Tmel_1639 Thermosipho melanesiensis BI429 hypothetical protein YP_001306868.1 1627739 R 391009 CDS YP_001306869.1 150021515 5297893 1628275..1629096 1 NC_009616.1 hypothetical protein 1629096 5297893 Tmel_1640 Thermosipho melanesiensis BI429 hypothetical protein YP_001306869.1 1628275 D 391009 CDS YP_001306870.1 150021516 5297894 complement(1629082..1630002) 1 NC_009616.1 hypothetical protein 1630002 5297894 Tmel_1641 Thermosipho melanesiensis BI429 hypothetical protein YP_001306870.1 1629082 R 391009 CDS YP_001306871.1 150021517 5297554 1630093..1631208 1 NC_009616.1 PFAM: YhhN family protein; YhhN family protein 1631208 5297554 Tmel_1642 Thermosipho melanesiensis BI429 YhhN family protein YP_001306871.1 1630093 D 391009 CDS YP_001306872.1 150021518 5296945 1631221..1632000 1 NC_009616.1 PFAM: protein of unknown function DUF152; hypothetical protein 1632000 5296945 Tmel_1643 Thermosipho melanesiensis BI429 hypothetical protein YP_001306872.1 1631221 D 391009 CDS YP_001306873.1 150021519 5296946 complement(1632234..1633379) 1 NC_009616.1 hypothetical protein 1633379 5296946 Tmel_1644 Thermosipho melanesiensis BI429 hypothetical protein YP_001306873.1 1632234 R 391009 CDS YP_001306874.1 150021520 5297684 1633576..1633845 1 NC_009616.1 PFAM: glutaredoxin 2; glutaredoxin 2 1633845 5297684 Tmel_1645 Thermosipho melanesiensis BI429 glutaredoxin 2 YP_001306874.1 1633576 D 391009 CDS YP_001306875.1 150021521 5297685 1633903..1634769 1 NC_009616.1 PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1634769 5297685 Tmel_1646 Thermosipho melanesiensis BI429 hypothetical protein YP_001306875.1 1633903 D 391009 CDS YP_001306876.1 150021522 5297135 complement(1635085..1636017) 1 NC_009616.1 hypothetical protein 1636017 5297135 Tmel_1647 Thermosipho melanesiensis BI429 hypothetical protein YP_001306876.1 1635085 R 391009 CDS YP_001306877.1 150021523 5297136 complement(1636022..1636756) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1636756 5297136 Tmel_1648 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306877.1 1636022 R 391009 CDS YP_001306878.1 150021524 5297957 complement(1636756..1637712) 1 NC_009616.1 multidrug ABC transporter ATPase and permease components-like protein 1637712 5297957 Tmel_1649 Thermosipho melanesiensis BI429 multidrug ABC transporter ATPase and permease components-like protein YP_001306878.1 1636756 R 391009 CDS YP_001306879.1 150021525 5297591 1640173..1640433 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein 1640433 5297591 Tmel_1650 Thermosipho melanesiensis BI429 CRISPR-associated Cas2 family protein YP_001306879.1 1640173 D 391009 CDS YP_001306880.1 150021526 5297592 1640446..1641432 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; CRISPR-associated Cas1 family protein 1641432 5297592 Tmel_1651 Thermosipho melanesiensis BI429 CRISPR-associated Cas1 family protein YP_001306880.1 1640446 D 391009 CDS YP_001306881.1 150021527 5298323 1641429..1641707 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein 1641707 5298323 Tmel_1652 Thermosipho melanesiensis BI429 CRISPR-associated Cas2 family protein YP_001306881.1 1641429 D 391009 CDS YP_001306882.1 150021528 5298324 1641942..1642049 1 NC_009616.1 hypothetical protein 1642049 5298324 Tmel_1653 Thermosipho melanesiensis BI429 hypothetical protein YP_001306882.1 1641942 D 391009 CDS YP_001306883.1 150021529 5298356 1642056..1642244 1 NC_009616.1 hypothetical protein 1642244 5298356 Tmel_1654 Thermosipho melanesiensis BI429 hypothetical protein YP_001306883.1 1642056 D 391009 CDS YP_001306884.1 150021530 5298357 1642292..1642474 1 NC_009616.1 hypothetical protein 1642474 5298357 Tmel_1655 Thermosipho melanesiensis BI429 hypothetical protein YP_001306884.1 1642292 D 391009 CDS YP_001306885.1 150021531 5298199 1642545..1643672 1 NC_009616.1 TIGRFAM: putative CRISPR-associated protein, APE2256 family; CRISPR-associated protein APE2256 family 1643672 5298199 Tmel_1656 Thermosipho melanesiensis BI429 CRISPR-associated protein APE2256 family YP_001306885.1 1642545 D 391009 CDS YP_001306886.1 150021532 5298178 1643708..1644832 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Cmr1 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr1 family protein 1644832 5298178 Tmel_1657 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Cmr1 family protein YP_001306886.1 1643708 D 391009 CDS YP_001306887.1 150021533 5298179 1644849..1647044 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, Crm2 family; CRISPR-associated RAMP Crm2 family protein 1647044 5298179 Tmel_1658 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Crm2 family protein YP_001306887.1 1644849 D 391009 CDS YP_001306888.1 150021534 5298126 1647034..1648005 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, Cmr3 family; CRISPR-associated Cmr3 family protein 1648005 5298126 Tmel_1659 Thermosipho melanesiensis BI429 CRISPR-associated Cmr3 family protein YP_001306888.1 1647034 D 391009 CDS YP_001306889.1 150021535 5298127 1648018..1648848 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr4 family protein 1648848 5298127 Tmel_1660 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Cmr4 family protein YP_001306889.1 1648018 D 391009 CDS YP_001306890.1 150021536 5298003 1648858..1649229 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, Cmr5 family; CRISPR-associated Cmr5 family protein 1649229 5298003 Tmel_1661 Thermosipho melanesiensis BI429 CRISPR-associated Cmr5 family protein YP_001306890.1 1648858 D 391009 CDS YP_001306891.1 150021537 5298004 1649247..1650062 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Cmr6 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr6 family protein 1650062 5298004 Tmel_1662 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Cmr6 family protein YP_001306891.1 1649247 D 391009 CDS YP_001306892.1 150021538 5297877 1652445..1652582 1 NC_009616.1 hypothetical protein 1652582 5297877 Tmel_1664 Thermosipho melanesiensis BI429 hypothetical protein YP_001306892.1 1652445 D 391009 CDS YP_001306893.1 150021539 5298171 1653099..1653404 1 NC_009616.1 hypothetical protein 1653404 5298171 Tmel_1665 Thermosipho melanesiensis BI429 hypothetical protein YP_001306893.1 1653099 D 391009 CDS YP_001306894.1 150021540 5298172 1653413..1654078 1 NC_009616.1 ECF subfamily RNA polymerase sigma-24 factor 1654078 5298172 Tmel_1666 Thermosipho melanesiensis BI429 ECF subfamily RNA polymerase sigma-24 factor YP_001306894.1 1653413 D 391009 CDS YP_001306895.1 150021541 5298106 1654097..1654867 1 NC_009616.1 hypothetical protein 1654867 5298106 Tmel_1667 Thermosipho melanesiensis BI429 hypothetical protein YP_001306895.1 1654097 D 391009 CDS YP_001306896.1 150021542 5298107 1654867..1656300 1 NC_009616.1 hypothetical protein 1656300 5298107 Tmel_1668 Thermosipho melanesiensis BI429 hypothetical protein YP_001306896.1 1654867 D 391009 CDS YP_001306897.1 150021543 5298063 1656302..1657708 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, MJ1666 family; CRISPR-associated DxTHG family protein 1657708 5298063 Tmel_1669 Thermosipho melanesiensis BI429 CRISPR-associated DxTHG family protein YP_001306897.1 1656302 D 391009 CDS YP_001306898.1 150021544 5298064 1657721..1659994 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase 1659994 5298064 Tmel_1670 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001306898.1 1657721 D 391009 CDS YP_001306899.1 150021545 5298387 1659996..1660436 1 NC_009616.1 TIGRFAM: CRISPR-associated protein, Csm2 family; CRISPR-associated Csm2 family protein 1660436 5298387 Tmel_1671 Thermosipho melanesiensis BI429 CRISPR-associated Csm2 family protein YP_001306899.1 1659996 D 391009 CDS YP_001306900.1 150021546 5298279 1660453..1661262 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm3 family protein 1661262 5298279 Tmel_1672 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Csm3 family protein YP_001306900.1 1660453 D 391009 CDS YP_001306901.1 150021547 5298280 1661267..1662208 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm4 family protein 1662208 5298280 Tmel_1673 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Csm4 family protein YP_001306901.1 1661267 D 391009 CDS YP_001306902.1 150021548 5298255 1662198..1663259 1 NC_009616.1 TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm5 family protein 1663259 5298255 Tmel_1674 Thermosipho melanesiensis BI429 CRISPR-associated RAMP Csm5 family protein YP_001306902.1 1662198 D 391009 CDS YP_001306903.1 150021549 5298256 1663256..1663846 1 NC_009616.1 hypothetical protein 1663846 5298256 Tmel_1675 Thermosipho melanesiensis BI429 hypothetical protein YP_001306903.1 1663256 D 391009 CDS YP_001306904.1 150021550 5298392 1663824..1664555 1 NC_009616.1 TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated Cas family protein 1664555 5298392 Tmel_1676 Thermosipho melanesiensis BI429 CRISPR-associated Cas family protein YP_001306904.1 1663824 D 391009 CDS YP_001306905.1 150021551 5298393 1664566..1665003 1 NC_009616.1 PFAM: ribonuclease H; ribonuclease H 1665003 5298393 Tmel_1677 Thermosipho melanesiensis BI429 ribonuclease H YP_001306905.1 1664566 D 391009 CDS YP_001306906.1 150021552 5298196 1665520..1665831 1 NC_009616.1 hypothetical protein 1665831 5298196 Tmel_1678 Thermosipho melanesiensis BI429 hypothetical protein YP_001306906.1 1665520 D 391009 CDS YP_001306907.1 150021553 5298181 1666141..1666356 1 NC_009616.1 hypothetical protein 1666356 5298181 Tmel_1679 Thermosipho melanesiensis BI429 hypothetical protein YP_001306907.1 1666141 D 391009 CDS YP_001306908.1 150021554 5296479 1666829..1667047 1 NC_009616.1 hypothetical protein 1667047 5296479 Tmel_1681 Thermosipho melanesiensis BI429 hypothetical protein YP_001306908.1 1666829 D 391009 CDS YP_001306909.1 150021555 5298154 complement(1667116..1667712) 1 NC_009616.1 TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; protein-L-isoaspartate O-methyltransferase 1667712 5298154 Tmel_1682 Thermosipho melanesiensis BI429 protein-L-isoaspartate O-methyltransferase YP_001306909.1 1667116 R 391009 CDS YP_001306910.1 150021556 5298155 1667978..1669348 1 NC_009616.1 PFAM: DUF234 DEXX-box ATPase; ATPase; ATPase 1669348 5298155 Tmel_1683 Thermosipho melanesiensis BI429 ATPase YP_001306910.1 1667978 D 391009 CDS YP_001306911.1 150021557 5298440 1669485..1669898 1 NC_009616.1 PFAM: protein of unknown function DUF262; hypothetical protein 1669898 5298440 Tmel_1684 Thermosipho melanesiensis BI429 hypothetical protein YP_001306911.1 1669485 D 391009 CDS YP_001306912.1 150021558 5298441 1669947..1671743 1 NC_009616.1 hypothetical protein 1671743 5298441 Tmel_1685 Thermosipho melanesiensis BI429 hypothetical protein YP_001306912.1 1669947 D 391009 CDS YP_001306913.1 150021559 5298142 1671833..1673929 1 NC_009616.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; type III restriction enzyme, res subunit 1673929 5298142 Tmel_1686 Thermosipho melanesiensis BI429 type III restriction enzyme, res subunit YP_001306913.1 1671833 D 391009 CDS YP_001306914.1 150021560 5298366 1673945..1674148 1 NC_009616.1 hypothetical protein 1674148 5298366 Tmel_1687 Thermosipho melanesiensis BI429 hypothetical protein YP_001306914.1 1673945 D 391009 CDS YP_001306915.1 150021561 5298367 1674154..1675437 1 NC_009616.1 hypothetical protein 1675437 5298367 Tmel_1688 Thermosipho melanesiensis BI429 hypothetical protein YP_001306915.1 1674154 D 391009 CDS YP_001306916.1 150021562 5298360 1675415..1675705 1 NC_009616.1 hypothetical protein 1675705 5298360 Tmel_1689 Thermosipho melanesiensis BI429 hypothetical protein YP_001306916.1 1675415 D 391009 CDS YP_001306917.1 150021563 5298361 1675699..1676106 1 NC_009616.1 hypothetical protein 1676106 5298361 Tmel_1690 Thermosipho melanesiensis BI429 hypothetical protein YP_001306917.1 1675699 D 391009 CDS YP_001306918.1 150021564 5298200 1676099..1678639 1 NC_009616.1 PFAM: DNA methylase N-4/N-6 domain protein; DNA methylase N-4/N-6 domain-containing protein 1678639 5298200 Tmel_1691 Thermosipho melanesiensis BI429 DNA methylase N-4/N-6 domain-containing protein YP_001306918.1 1676099 D 391009 CDS YP_001306919.1 150021565 5298201 1678644..1681568 1 NC_009616.1 PFAM: type III restriction enzyme, res subunit; type III restriction enzyme, res subunit 1681568 5298201 Tmel_1692 Thermosipho melanesiensis BI429 type III restriction enzyme, res subunit YP_001306919.1 1678644 D 391009 CDS YP_001306920.1 150021566 5296480 1682033..1682326 1 NC_009616.1 PFAM: DNA polymerase, beta domain protein region; DNA polymerase subunit beta 1682326 5296480 Tmel_1694 Thermosipho melanesiensis BI429 DNA polymerase subunit beta YP_001306920.1 1682033 D 391009 CDS YP_001306921.1 150021567 5298031 1682323..1682670 1 NC_009616.1 PFAM: protein of unknown function DUF86; hypothetical protein 1682670 5298031 Tmel_1695 Thermosipho melanesiensis BI429 hypothetical protein YP_001306921.1 1682323 D 391009 CDS YP_001306922.1 150021568 5297969 1683001..1683360 1 NC_009616.1 hypothetical protein 1683360 5297969 Tmel_1697 Thermosipho melanesiensis BI429 hypothetical protein YP_001306922.1 1683001 D 391009 CDS YP_001306923.1 150021569 5297970 complement(1684449..1685714) 1 NC_009616.1 PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter 1685714 5297970 Tmel_1699 Thermosipho melanesiensis BI429 citrate transporter YP_001306923.1 1684449 R 391009 CDS YP_001306924.1 150021570 5298241 1685964..1686233 1 NC_009616.1 PFAM: glutaredoxin 2; glutaredoxin 2 1686233 5298241 Tmel_1700 Thermosipho melanesiensis BI429 glutaredoxin 2 YP_001306924.1 1685964 D 391009 CDS YP_001306925.1 150021571 5298252 complement(1686311..1687606) 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1687606 5298252 Tmel_1701 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001306925.1 1686311 R 391009 CDS YP_001306926.1 150021572 5298253 complement(1687603..1688703) 1 NC_009616.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein 1688703 5298253 Tmel_1702 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306926.1 1687603 R 391009 CDS YP_001306927.1 150021573 5298254 complement(1688748..1690028) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1690028 5298254 Tmel_1703 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306927.1 1688748 R 391009 CDS YP_001306928.1 150021574 5298244 complement(1690028..1690897) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1690897 5298244 Tmel_1704 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306928.1 1690028 R 391009 CDS YP_001306929.1 150021575 5298245 complement(1690972..1691823) 1 NC_009616.1 sugar ABC transporter periplasmic component-like protein 1691823 5298245 Tmel_1705 Thermosipho melanesiensis BI429 sugar ABC transporter periplasmic component-like protein YP_001306929.1 1690972 R 391009 CDS YP_001306930.1 150021576 5298246 complement(1691857..1692180) 1 NC_009616.1 hypothetical protein 1692180 5298246 Tmel_1706 Thermosipho melanesiensis BI429 hypothetical protein YP_001306930.1 1691857 R 391009 CDS YP_001306931.1 150021577 5298247 1692348..1693040 1 NC_009616.1 hypothetical protein 1693040 5298247 Tmel_1707 Thermosipho melanesiensis BI429 hypothetical protein YP_001306931.1 1692348 D 391009 CDS YP_001306932.1 150021578 5298434 complement(1693391..1694155) 1 NC_009616.1 PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 1694155 5298434 Tmel_1708 Thermosipho melanesiensis BI429 iron-containing alcohol dehydrogenase YP_001306932.1 1693391 R 391009 CDS YP_001306933.1 150021579 5298435 complement(1694348..1694680) 1 NC_009616.1 PFAM: protein of unknown function DUF1291; hypothetical protein 1694680 5298435 Tmel_1709 Thermosipho melanesiensis BI429 hypothetical protein YP_001306933.1 1694348 R 391009 CDS YP_001306934.1 150021580 5298010 complement(1694677..1695393) 1 NC_009616.1 PFAM: DNA alkylation repair enzyme; DNA alkylation repair enzyme 1695393 5298010 Tmel_1710 Thermosipho melanesiensis BI429 DNA alkylation repair enzyme YP_001306934.1 1694677 R 391009 CDS YP_001306935.1 150021581 5298466 complement(1695680..1696744) 1 NC_009616.1 TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; protein phosphatase 2C domain protein; putative PAS/PAC sensor protein 1696744 5298466 Tmel_1711 Thermosipho melanesiensis BI429 putative PAS/PAC sensor protein YP_001306935.1 1695680 R 391009 CDS YP_001306936.1 150021582 5298467 complement(1697471..1698163) 1 NC_009616.1 hypothetical protein 1698163 5298467 Tmel_1712 Thermosipho melanesiensis BI429 hypothetical protein YP_001306936.1 1697471 R 391009 CDS YP_001306937.1 150021583 5297050 1698350..1699558 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 1699558 5297050 Tmel_1713 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001306937.1 1698350 D 391009 CDS YP_001306938.1 150021584 5297051 1699609..1700478 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1700478 5297051 Tmel_1714 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306938.1 1699609 D 391009 CDS YP_001306939.1 150021585 5297443 1700478..1701758 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1701758 5297443 Tmel_1715 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306939.1 1700478 D 391009 CDS YP_001306940.1 150021586 5297444 1701789..1702886 1 NC_009616.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein 1702886 5297444 Tmel_1716 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306940.1 1701789 D 391009 CDS YP_001306941.1 150021587 5297636 1702886..1704187 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1704187 5297636 Tmel_1717 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001306941.1 1702886 D 391009 CDS YP_001306942.1 150021588 5298075 complement(1704236..1704511) 1 NC_009616.1 hypothetical protein 1704511 5298075 Tmel_1718 Thermosipho melanesiensis BI429 hypothetical protein YP_001306942.1 1704236 R 391009 CDS YP_001306943.1 150021589 5298076 complement(1704541..1704870) 1 NC_009616.1 hypothetical protein 1704870 5298076 Tmel_1719 Thermosipho melanesiensis BI429 hypothetical protein YP_001306943.1 1704541 R 391009 CDS YP_001306944.1 150021590 5298460 1705312..1705983 1 NC_009616.1 P-loop ATPase-like protein 1705983 5298460 Tmel_1720 Thermosipho melanesiensis BI429 P-loop ATPase-like protein YP_001306944.1 1705312 D 391009 CDS YP_001306945.1 150021591 5298461 1706028..1706354 1 NC_009616.1 hypothetical protein 1706354 5298461 Tmel_1721 Thermosipho melanesiensis BI429 hypothetical protein YP_001306945.1 1706028 D 391009 CDS YP_001306946.1 150021592 5297319 1706735..1707493 1 NC_009616.1 PFAM: protein of unknown function DUF81; hypothetical protein 1707493 5297319 Tmel_1722 Thermosipho melanesiensis BI429 hypothetical protein YP_001306946.1 1706735 D 391009 CDS YP_001306947.1 150021593 5297320 1707511..1708908 1 NC_009616.1 TIGRFAM: dipeptidase, putative; PFAM: peptidase M20; dipeptidase 1708908 5297320 Tmel_1723 Thermosipho melanesiensis BI429 dipeptidase YP_001306947.1 1707511 D 391009 CDS YP_001306948.1 150021594 5297511 complement(1709480..1710688) 1 NC_009616.1 hypothetical protein 1710688 5297511 Tmel_1724 Thermosipho melanesiensis BI429 hypothetical protein YP_001306948.1 1709480 R 391009 CDS YP_001306949.1 150021595 5296706 1710856..1711422 1 NC_009616.1 hypothetical protein 1711422 5296706 Tmel_1725 Thermosipho melanesiensis BI429 hypothetical protein YP_001306949.1 1710856 D 391009 CDS YP_001306950.1 150021596 5296707 complement(1711484..1713208) 1 NC_009616.1 PFAM: penicillin-binding protein, transpeptidase; peptidoglycan glycosyltransferase 1713208 5296707 Tmel_1726 Thermosipho melanesiensis BI429 peptidoglycan glycosyltransferase YP_001306950.1 1711484 R 391009 CDS YP_001306951.1 150021597 5296650 complement(1713481..1714356) 1 NC_009616.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; S-adenosyl-methyltransferase MraW 1714356 mraW 5296650 mraW Thermosipho melanesiensis BI429 S-adenosyl-methyltransferase MraW YP_001306951.1 1713481 R 391009 CDS YP_001306952.1 150021598 5296651 complement(1714531..1715889) 1 NC_009616.1 PFAM: amidohydrolase; hydroxydechloroatrazine ethylaminohydrolase 1715889 5296651 Tmel_1728 Thermosipho melanesiensis BI429 hydroxydechloroatrazine ethylaminohydrolase YP_001306952.1 1714531 R 391009 CDS YP_001306953.1 150021599 5296631 complement(1715900..1717312) 1 NC_009616.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta 1717312 5296631 Tmel_1729 Thermosipho melanesiensis BI429 pyridoxal-5'-phosphate-dependent enzyme subunit beta YP_001306953.1 1715900 R 391009 CDS YP_001306954.1 150021600 5296632 complement(1717317..1719581) 1 NC_009616.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 1719581 5296632 Tmel_1730 Thermosipho melanesiensis BI429 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_001306954.1 1717317 R 391009 CDS YP_001306955.1 150021601 5297092 complement(1719585..1721309) 1 NC_009616.1 TIGRFAM: adenine deaminase; PFAM: amidohydrolase; adenine deaminase 1721309 5297092 Tmel_1731 Thermosipho melanesiensis BI429 adenine deaminase YP_001306955.1 1719585 R 391009 CDS YP_001306956.1 150021602 5297093 complement(1721545..1722684) 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1722684 5297093 Tmel_1732 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306956.1 1721545 R 391009 CDS YP_001306957.1 150021603 5297199 complement(1722681..1723697) 1 NC_009616.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1723697 5297199 Tmel_1733 Thermosipho melanesiensis BI429 oligopeptide/dipeptide ABC transporter ATPase YP_001306957.1 1722681 R 391009 CDS YP_001306958.1 150021604 5297355 complement(1723711..1724625) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1724625 5297355 Tmel_1734 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306958.1 1723711 R 391009 CDS YP_001306959.1 150021605 5297356 complement(1724640..1725677) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1725677 5297356 Tmel_1735 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001306959.1 1724640 R 391009 CDS YP_001306960.1 150021606 5297078 complement(1725799..1727451) 1 NC_009616.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1727451 uvrC 5297078 uvrC Thermosipho melanesiensis BI429 excinuclease ABC subunit C YP_001306960.1 1725799 R 391009 CDS YP_001306961.1 150021607 5297079 complement(1727514..1727954) 1 NC_009616.1 hypothetical protein 1727954 5297079 Tmel_1737 Thermosipho melanesiensis BI429 hypothetical protein YP_001306961.1 1727514 R 391009 CDS YP_001306962.1 150021608 5296697 complement(1727954..1728322) 1 NC_009616.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 1728322 5296697 Tmel_1738 Thermosipho melanesiensis BI429 glycine cleavage system protein H YP_001306962.1 1727954 R 391009 CDS YP_001306963.1 150021609 5296698 complement(1728426..1730366) 1 NC_009616.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; ferrous iron transport protein B 1730366 5296698 Tmel_1739 Thermosipho melanesiensis BI429 ferrous iron transport protein B YP_001306963.1 1728426 R 391009 CDS YP_001306964.1 150021610 5296722 complement(1730368..1730796) 1 NC_009616.1 PFAM: FeoA family protein; FeoA family protein 1730796 5296722 Tmel_1740 Thermosipho melanesiensis BI429 FeoA family protein YP_001306964.1 1730368 R 391009 CDS YP_001306965.1 150021611 5296723 complement(1731267..1731821) 1 NC_009616.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1; helix-hairpin-helix repeat-containing competence protein ComEA 1731821 5296723 Tmel_1741 Thermosipho melanesiensis BI429 helix-hairpin-helix repeat-containing competence protein ComEA YP_001306965.1 1731267 R 391009 CDS YP_001306966.1 150021612 5297288 complement(1731815..1732603) 1 NC_009616.1 PFAM: protein of unknown function DUF52; hypothetical protein 1732603 5297288 Tmel_1742 Thermosipho melanesiensis BI429 hypothetical protein YP_001306966.1 1731815 R 391009 CDS YP_001306967.1 150021613 5297597 complement(1732603..1736511) 1 NC_009616.1 PFAM: type II and III secretion system protein; type II and III secretion system protein 1736511 5297597 Tmel_1743 Thermosipho melanesiensis BI429 type II and III secretion system protein YP_001306967.1 1732603 R 391009 CDS YP_001306968.1 150021614 5297598 complement(1736511..1736957) 1 NC_009616.1 hypothetical protein 1736957 5297598 Tmel_1744 Thermosipho melanesiensis BI429 hypothetical protein YP_001306968.1 1736511 R 391009 CDS YP_001306969.1 150021615 5297180 complement(1736950..1737375) 1 NC_009616.1 hypothetical protein 1737375 5297180 Tmel_1745 Thermosipho melanesiensis BI429 hypothetical protein YP_001306969.1 1736950 R 391009 CDS YP_001306970.1 150021616 5297181 complement(1737372..1737929) 1 NC_009616.1 hypothetical protein 1737929 5297181 Tmel_1746 Thermosipho melanesiensis BI429 hypothetical protein YP_001306970.1 1737372 R 391009 CDS YP_001306971.1 150021617 5297706 complement(1737907..1738851) 1 NC_009616.1 hypothetical protein 1738851 5297706 Tmel_1747 Thermosipho melanesiensis BI429 hypothetical protein YP_001306971.1 1737907 R 391009 CDS YP_001306972.1 150021618 5297707 complement(1738862..1739218) 1 NC_009616.1 hypothetical protein 1739218 5297707 Tmel_1748 Thermosipho melanesiensis BI429 hypothetical protein YP_001306972.1 1738862 R 391009 CDS YP_001306973.1 150021619 5297562 complement(1739220..1740413) 1 NC_009616.1 PFAM: type II secretion system protein; type II secretion system protein 1740413 5297562 Tmel_1749 Thermosipho melanesiensis BI429 type II secretion system protein YP_001306973.1 1739220 R 391009 CDS YP_001306974.1 150021620 5297563 complement(1740403..1741083) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1741083 5297563 Tmel_1750 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001306974.1 1740403 R 391009 CDS YP_001306975.1 150021621 5296587 complement(1741080..1741676) 1 NC_009616.1 PFAM: methyltransferase small; Methyltransferase type 12; methyltransferase small 1741676 5296587 Tmel_1751 Thermosipho melanesiensis BI429 methyltransferase small YP_001306975.1 1741080 R 391009 CDS YP_001306976.1 150021622 5297097 complement(1741676..1742134) 1 NC_009616.1 PFAM: flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein 1742134 5297097 Tmel_1752 Thermosipho melanesiensis BI429 flavin reductase domain-containing protein YP_001306976.1 1741676 R 391009 CDS YP_001306977.1 150021623 5297098 1742269..1744125 1 NC_009616.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1744125 5297098 Tmel_1753 Thermosipho melanesiensis BI429 transketolase YP_001306977.1 1742269 D 391009 CDS YP_001306978.1 150021624 5297264 complement(1744164..1744565) 1 NC_009616.1 hypothetical protein 1744565 5297264 Tmel_1754 Thermosipho melanesiensis BI429 hypothetical protein YP_001306978.1 1744164 R 391009 CDS YP_001306979.1 150021625 5297265 complement(1744580..1744855) 1 NC_009616.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1744855 rpsT 5297265 rpsT Thermosipho melanesiensis BI429 30S ribosomal protein S20 YP_001306979.1 1744580 R 391009 CDS YP_001306980.1 150021626 5297168 complement(1744873..1746060) 1 NC_009616.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1746060 5297168 Tmel_1756 Thermosipho melanesiensis BI429 S-adenosylmethionine synthetase YP_001306980.1 1744873 R 391009 CDS YP_001306981.1 150021627 5297169 complement(1746057..1746371) 1 NC_009616.1 hypothetical protein 1746371 5297169 Tmel_1757 Thermosipho melanesiensis BI429 hypothetical protein YP_001306981.1 1746057 R 391009 CDS YP_001306982.1 150021628 5296835 complement(1746374..1747339) 1 NC_009616.1 PFAM: peptidase M23B; peptidase M23B 1747339 5296835 Tmel_1758 Thermosipho melanesiensis BI429 peptidase M23B YP_001306982.1 1746374 R 391009 CDS YP_001306983.1 150021629 5296836 complement(1747336..1748421) 1 NC_009616.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; small GTP-binding protein 1748421 5296836 Tmel_1759 Thermosipho melanesiensis BI429 small GTP-binding protein YP_001306983.1 1747336 R 391009 CDS YP_001306984.1 150021630 5297075 complement(1748408..1748668) 1 NC_009616.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; RNA chaperone Hfq 1748668 5297075 Tmel_1760 Thermosipho melanesiensis BI429 RNA chaperone Hfq YP_001306984.1 1748408 R 391009 CDS YP_001306985.1 150021631 5296837 complement(1748671..1749105) 1 NC_009616.1 hypothetical protein 1749105 5296837 Tmel_1761 Thermosipho melanesiensis BI429 hypothetical protein YP_001306985.1 1748671 R 391009 CDS YP_001306986.1 150021632 5296838 complement(1749102..1750001) 1 NC_009616.1 hypothetical protein 1750001 5296838 Tmel_1762 Thermosipho melanesiensis BI429 hypothetical protein YP_001306986.1 1749102 R 391009 CDS YP_001306987.1 150021633 5297493 complement(1749998..1751677) 1 NC_009616.1 PFAM: phosphoribulokinase/uridine kinase; phosphoribulokinase/uridine kinase 1751677 5297493 Tmel_1763 Thermosipho melanesiensis BI429 phosphoribulokinase/uridine kinase YP_001306987.1 1749998 R 391009 CDS YP_001306988.1 150021634 5297494 complement(1751690..1753087) 1 NC_009616.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; ribonuclease 1753087 5297494 Tmel_1764 Thermosipho melanesiensis BI429 ribonuclease YP_001306988.1 1751690 R 391009 CDS YP_001306989.1 150021635 5296565 complement(1753092..1754291) 1 NC_009616.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 1754291 5296565 Tmel_1765 Thermosipho melanesiensis BI429 S-adenosyl-L-homocysteine hydrolase YP_001306989.1 1753092 R 391009 CDS YP_001306990.1 150021636 5296566 1754468..1754980 1 NC_009616.1 PFAM: CMP/dCMP deaminase, zinc-binding; zinc-binding CMP/dCMP deaminase 1754980 5296566 Tmel_1766 Thermosipho melanesiensis BI429 zinc-binding CMP/dCMP deaminase YP_001306990.1 1754468 D 391009 CDS YP_001306991.1 150021637 5297059 1754967..1755791 1 NC_009616.1 catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1755791 5297059 Tmel_1767 Thermosipho melanesiensis BI429 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_001306991.1 1754967 D 391009 CDS YP_001306992.1 150021638 5297060 1755795..1756397 1 NC_009616.1 TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase subunit gamma 1756397 5297060 Tmel_1768 Thermosipho melanesiensis BI429 pyruvate/ketoisovalerate oxidoreductase subunit gamma YP_001306992.1 1755795 D 391009 CDS YP_001306993.1 150021639 5296967 1756384..1756833 1 NC_009616.1 PFAM: diacylglycerol kinase; diacylglycerol kinase 1756833 5296967 Tmel_1769 Thermosipho melanesiensis BI429 diacylglycerol kinase YP_001306993.1 1756384 D 391009 CDS YP_001306994.1 150021640 5297339 1756818..1757852 1 NC_009616.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1757852 5297339 Tmel_1770 Thermosipho melanesiensis BI429 chemotaxis-specific methylesterase YP_001306994.1 1756818 D 391009 CDS YP_001306995.1 150021641 5297340 1757867..1758952 1 NC_009616.1 PFAM: S-layer domain protein domain protein; S-layer domain-containing protein 1758952 5297340 Tmel_1771 Thermosipho melanesiensis BI429 S-layer domain-containing protein YP_001306995.1 1757867 D 391009 CDS YP_001306996.1 150021642 5297941 complement(1764394..1766388) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1766388 5297941 Tmel_1776 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001306996.1 1764394 R 391009 CDS YP_001306997.1 150021643 5297345 complement(1766385..1767902) 1 NC_009616.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 1767902 5297345 Tmel_1777 Thermosipho melanesiensis BI429 histidine ammonia-lyase YP_001306997.1 1766385 R 391009 CDS YP_001306998.1 150021644 5296714 complement(1767899..1768420) 1 NC_009616.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; ATP--cobalamin adenosyltransferase 1768420 5296714 Tmel_1778 Thermosipho melanesiensis BI429 ATP--cobalamin adenosyltransferase YP_001306998.1 1767899 R 391009 CDS YP_001306999.1 150021645 5296715 complement(1768420..1769163) 1 NC_009616.1 hypothetical protein 1769163 5296715 Tmel_1779 Thermosipho melanesiensis BI429 hypothetical protein YP_001306999.1 1768420 R 391009 CDS YP_001307000.1 150021646 5296512 complement(1769166..1769897) 1 NC_009616.1 hypothetical protein 1769897 5296512 Tmel_1780 Thermosipho melanesiensis BI429 hypothetical protein YP_001307000.1 1769166 R 391009 CDS YP_001307001.1 150021647 5296513 complement(1769902..1770411) 1 NC_009616.1 PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 1770411 5296513 Tmel_1781 Thermosipho melanesiensis BI429 GCN5-like N-acetyltransferase YP_001307001.1 1769902 R 391009 CDS YP_001307002.1 150021648 5297010 complement(1770401..1771216) 1 NC_009616.1 PFAM: metallophosphoesterase; metallophosphoesterase 1771216 5297010 Tmel_1782 Thermosipho melanesiensis BI429 metallophosphoesterase YP_001307002.1 1770401 R 391009 CDS YP_001307003.1 150021649 5296914 complement(1771213..1771443) 1 NC_009616.1 hypothetical protein 1771443 5296914 Tmel_1783 Thermosipho melanesiensis BI429 hypothetical protein YP_001307003.1 1771213 R 391009 CDS YP_001307004.1 150021650 5296915 complement(1771433..1771930) 1 NC_009616.1 PFAM: iron dependent repressor; iron dependent repressor 1771930 5296915 Tmel_1784 Thermosipho melanesiensis BI429 iron dependent repressor YP_001307004.1 1771433 R 391009 CDS YP_001307005.1 150021651 5296912 complement(1771969..1773000) 1 NC_009616.1 PFAM: peptidase M42 family protein; peptidase M42 family protein 1773000 5296912 Tmel_1785 Thermosipho melanesiensis BI429 peptidase M42 family protein YP_001307005.1 1771969 R 391009 CDS YP_001307006.1 150021652 5296913 complement(1773001..1773648) 1 NC_009616.1 hypothetical protein 1773648 5296913 Tmel_1786 Thermosipho melanesiensis BI429 hypothetical protein YP_001307006.1 1773001 R 391009 CDS YP_001307007.1 150021653 5297461 complement(1773645..1773899) 1 NC_009616.1 hypothetical protein 1773899 5297461 Tmel_1787 Thermosipho melanesiensis BI429 hypothetical protein YP_001307007.1 1773645 R 391009 CDS YP_001307008.1 150021654 5297462 complement(1773896..1774141) 1 NC_009616.1 hypothetical protein 1774141 5297462 Tmel_1788 Thermosipho melanesiensis BI429 hypothetical protein YP_001307008.1 1773896 R 391009 CDS YP_001307009.1 150021655 5297239 complement(1774143..1774487) 1 NC_009616.1 hypothetical protein 1774487 5297239 Tmel_1789 Thermosipho melanesiensis BI429 hypothetical protein YP_001307009.1 1774143 R 391009 CDS YP_001307010.1 150021656 5297240 complement(1774475..1775446) 1 NC_009616.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; glycerol-3-phosphate dehydrogenase 1775446 5297240 Tmel_1790 Thermosipho melanesiensis BI429 glycerol-3-phosphate dehydrogenase YP_001307010.1 1774475 R 391009 CDS YP_001307011.1 150021657 5297031 complement(1775443..1776378) 1 NC_009616.1 TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: putative methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 1776378 5297031 Tmel_1791 Thermosipho melanesiensis BI429 tRNA (guanine-N(7)-)-methyltransferase YP_001307011.1 1775443 R 391009 CDS YP_001307012.1 150021658 5296892 complement(1776375..1777478) 1 NC_009616.1 PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein 1777478 5296892 Tmel_1792 Thermosipho melanesiensis BI429 TPR repeat-containing protein YP_001307012.1 1776375 R 391009 CDS YP_001307013.1 150021659 5296893 complement(1777481..1778986) 1 NC_009616.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; carbohydrate kinase, YjeF-like protein 1778986 5296893 Tmel_1793 Thermosipho melanesiensis BI429 carbohydrate kinase, YjeF-like protein YP_001307013.1 1777481 R 391009 CDS YP_001307014.1 150021660 5297514 complement(1778989..1779447) 1 NC_009616.1 PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase 1779447 5297514 Tmel_1794 Thermosipho melanesiensis BI429 lytic transglycosylase YP_001307014.1 1778989 R 391009 CDS YP_001307015.1 150021661 5297515 complement(1779458..1780156) 1 NC_009616.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; peptidase A24A domain-containing protein 1780156 5297515 Tmel_1795 Thermosipho melanesiensis BI429 peptidase A24A domain-containing protein YP_001307015.1 1779458 R 391009 CDS YP_001307016.1 150021662 5297714 complement(1780141..1781199) 1 NC_009616.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein 1781199 5297714 Tmel_1796 Thermosipho melanesiensis BI429 TPR repeat-containing protein YP_001307016.1 1780141 R 391009 CDS YP_001307017.1 150021663 5297715 1781355..1782713 1 NC_009616.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 1782713 5297715 Tmel_1797 Thermosipho melanesiensis BI429 protease Do YP_001307017.1 1781355 D 391009 CDS YP_001307018.1 150021664 5297176 1782906..1785392 1 NC_009616.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35; glycogen/starch/alpha-glucan phosphorylase 1785392 5297176 Tmel_1798 Thermosipho melanesiensis BI429 glycogen/starch/alpha-glucan phosphorylase YP_001307018.1 1782906 D 391009 CDS YP_001307019.1 150021665 5297177 complement(1785420..1786286) 1 NC_009616.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; signal peptidase I 1786286 5297177 Tmel_1799 Thermosipho melanesiensis BI429 signal peptidase I YP_001307019.1 1785420 R 391009 CDS YP_001307020.1 150021666 5296884 complement(1786292..1786639) 1 NC_009616.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1786639 rplS 5296884 rplS Thermosipho melanesiensis BI429 50S ribosomal protein L19 YP_001307020.1 1786292 R 391009 CDS YP_001307021.1 150021667 5297029 complement(1786654..1787220) 1 NC_009616.1 hypothetical protein 1787220 5297029 Tmel_1801 Thermosipho melanesiensis BI429 hypothetical protein YP_001307021.1 1786654 R 391009 CDS YP_001307022.1 150021668 5297030 complement(1787210..1787950) 1 NC_009616.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1787950 trmD 5297030 trmD Thermosipho melanesiensis BI429 tRNA (guanine-N(1)-)-methyltransferase YP_001307022.1 1787210 R 391009 CDS YP_001307023.1 150021669 5297346 complement(1787947..1788483) 1 NC_009616.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; 16S rRNA processing protein RimM 1788483 5297346 Tmel_1803 Thermosipho melanesiensis BI429 16S rRNA processing protein RimM YP_001307023.1 1787947 R 391009 CDS YP_001307024.1 150021670 5297347 complement(1788480..1788704) 1 NC_009616.1 RNA-binding protein 1788704 5297347 Tmel_1804 Thermosipho melanesiensis BI429 RNA-binding protein YP_001307024.1 1788480 R 391009 CDS YP_001307025.1 150021671 5296537 complement(1788701..1788988) 1 NC_009616.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1788988 rpsP 5296537 rpsP Thermosipho melanesiensis BI429 30S ribosomal protein S16 YP_001307025.1 1788701 R 391009 CDS YP_001307026.1 150021672 5296538 complement(1789010..1790317) 1 NC_009616.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase; signal recognition particle protein 1790317 5296538 Tmel_1806 Thermosipho melanesiensis BI429 signal recognition particle protein YP_001307026.1 1789010 R 391009 CDS YP_001307027.1 150021673 5296748 1790669..1791646 1 NC_009616.1 TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein, family 1; ABC transporter periplasmic-binding protein 1791646 5296748 Tmel_1807 Thermosipho melanesiensis BI429 ABC transporter periplasmic-binding protein YP_001307027.1 1790669 D 391009 CDS YP_001307028.1 150021674 5296749 1791619..1793151 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1793151 5296749 Tmel_1808 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001307028.1 1791619 D 391009 CDS YP_001307029.1 150021675 5296562 complement(1793148..1794014) 1 NC_009616.1 PFAM: Rubrerythrin; protein of unknown function DUF125, transmembrane; hypothetical protein 1794014 5296562 Tmel_1809 Thermosipho melanesiensis BI429 hypothetical protein YP_001307029.1 1793148 R 391009 CDS YP_001307030.1 150021676 5296499 complement(1794016..1794792) 1 NC_009616.1 PFAM: protein of unknown function DUF364; hypothetical protein 1794792 5296499 Tmel_1810 Thermosipho melanesiensis BI429 hypothetical protein YP_001307030.1 1794016 R 391009 CDS YP_001307031.1 150021677 5296500 complement(1794805..1795419) 1 NC_009616.1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites; N-glycosylase/DNA lyase 1795419 5296500 Tmel_1811 Thermosipho melanesiensis BI429 N-glycosylase/DNA lyase YP_001307031.1 1794805 R 391009 CDS YP_001307032.1 150021678 5297378 1795540..1796298 1 NC_009616.1 response regulator receiver/SARP domain-containing protein 1796298 5297378 Tmel_1812 Thermosipho melanesiensis BI429 response regulator receiver/SARP domain-containing protein YP_001307032.1 1795540 D 391009 CDS YP_001307033.1 150021679 5297379 complement(1796314..1797159) 1 NC_009616.1 hypothetical protein 1797159 5297379 Tmel_1813 Thermosipho melanesiensis BI429 hypothetical protein YP_001307033.1 1796314 R 391009 CDS YP_001307034.1 150021680 5297270 complement(1797206..1798144) 1 NC_009616.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1798144 5297270 Tmel_1814 Thermosipho melanesiensis BI429 ornithine carbamoyltransferase YP_001307034.1 1797206 R 391009 CDS YP_001307035.1 150021681 5297271 complement(1798187..1799521) 1 NC_009616.1 GTPase-like protein 1799521 5297271 Tmel_1815 Thermosipho melanesiensis BI429 GTPase-like protein YP_001307035.1 1798187 R 391009 CDS YP_001307036.1 150021682 5297463 complement(1799741..1801285) 1 NC_009616.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1801285 5297463 Tmel_1816 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001307036.1 1799741 R 391009 CDS YP_001307037.1 150021683 5297464 complement(1801310..1802650) 1 NC_009616.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1802650 5297464 Tmel_1817 Thermosipho melanesiensis BI429 metal dependent phosphohydrolase YP_001307037.1 1801310 R 391009 CDS YP_001307038.1 150021684 5296983 complement(1802793..1803632) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1803632 5296983 Tmel_1818 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001307038.1 1802793 R 391009 CDS YP_001307039.1 150021685 5297465 complement(1803644..1804525) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1804525 5297465 Tmel_1819 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001307039.1 1803644 R 391009 CDS YP_001307040.1 150021686 5297466 complement(1804569..1805804) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 1805804 5297466 Tmel_1820 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001307040.1 1804569 R 391009 CDS YP_001307041.1 150021687 5297844 1806136..1807347 1 NC_009616.1 PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1807347 5297844 Tmel_1821 Thermosipho melanesiensis BI429 group 1 glycosyl transferase YP_001307041.1 1806136 D 391009 CDS YP_001307042.1 150021688 5297845 1807505..1808461 1 NC_009616.1 PFAM: ROK family protein; ROK family protein 1808461 5297845 Tmel_1822 Thermosipho melanesiensis BI429 ROK family protein YP_001307042.1 1807505 D 391009 CDS YP_001307043.1 150021689 5297011 complement(1808445..1809404) 1 NC_009616.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; histidine kinase 1809404 5297011 Tmel_1823 Thermosipho melanesiensis BI429 histidine kinase YP_001307043.1 1808445 R 391009 CDS YP_001307044.1 150021690 5297012 complement(1809382..1810050) 1 NC_009616.1 PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator 1810050 5297012 Tmel_1824 Thermosipho melanesiensis BI429 two component transcriptional regulator YP_001307044.1 1809382 R 391009 CDS YP_001307045.1 150021691 5296732 complement(1810047..1810697) 1 NC_009616.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; phosphate uptake regulator PhoU 1810697 5296732 Tmel_1825 Thermosipho melanesiensis BI429 phosphate uptake regulator PhoU YP_001307045.1 1810047 R 391009 CDS YP_001307046.1 150021692 5296733 complement(1810709..1811461) 1 NC_009616.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 1811461 5296733 Tmel_1826 Thermosipho melanesiensis BI429 phosphate ABC transporter ATP-binding protein YP_001307046.1 1810709 R 391009 CDS YP_001307047.1 150021693 5296898 complement(1811458..1812270) 1 NC_009616.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; phosphate ABC transporter inner membrane subunit PstA 1812270 5296898 Tmel_1827 Thermosipho melanesiensis BI429 phosphate ABC transporter inner membrane subunit PstA YP_001307047.1 1811458 R 391009 CDS YP_001307048.1 150021694 5297928 complement(1812263..1813120) 1 NC_009616.1 PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1813120 5297928 Tmel_1828 Thermosipho melanesiensis BI429 binding-protein-dependent transport systems inner membrane component YP_001307048.1 1812263 R 391009 CDS YP_001307049.1 150021695 5297929 complement(1813132..1813953) 1 NC_009616.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1; phosphate binding protein 1813953 5297929 Tmel_1829 Thermosipho melanesiensis BI429 phosphate binding protein YP_001307049.1 1813132 R 391009 CDS YP_001307050.1 150021696 5297364 complement(1814069..1815394) 1 NC_009616.1 PFAM: aldehyde dehydrogenase; aldehyde dehydrogenase 1815394 5297364 Tmel_1830 Thermosipho melanesiensis BI429 aldehyde dehydrogenase YP_001307050.1 1814069 R 391009 CDS YP_001307051.1 150021697 5297365 complement(1815366..1815920) 1 NC_009616.1 PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase 1815920 5297365 Tmel_1831 Thermosipho melanesiensis BI429 GCN5-like N-acetyltransferase YP_001307051.1 1815366 R 391009 CDS YP_001307052.1 150021698 5297120 1816091..1816516 1 NC_009616.1 PFAM: regulatory protein, MarR; MarR family transcriptional regulator 1816516 5297120 Tmel_1832 Thermosipho melanesiensis BI429 MarR family transcriptional regulator YP_001307052.1 1816091 D 391009 CDS YP_001307053.1 150021699 5297121 1816518..1817525 1 NC_009616.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; NAD-dependent epimerase/dehydratase 1817525 5297121 Tmel_1833 Thermosipho melanesiensis BI429 NAD-dependent epimerase/dehydratase YP_001307053.1 1816518 D 391009 CDS YP_001307054.1 150021700 5297675 complement(1817496..1818416) 1 NC_009616.1 PFAM: PfkB domain protein; ribokinase-like domain-containing protein 1818416 5297675 Tmel_1834 Thermosipho melanesiensis BI429 ribokinase-like domain-containing protein YP_001307054.1 1817496 R 391009 CDS YP_001307055.1 150021701 5297676 complement(1818456..1819190) 1 NC_009616.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; 3-oxoacyl-(acyl-carrier-protein) reductase 1819190 5297676 Tmel_1835 Thermosipho melanesiensis BI429 3-oxoacyl-(acyl-carrier-protein) reductase YP_001307055.1 1818456 R 391009 CDS YP_001307056.1 150021702 5297064 complement(1819254..1819988) 1 NC_009616.1 PFAM: cobalt transport protein; cobalt transport protein 1819988 5297064 Tmel_1836 Thermosipho melanesiensis BI429 cobalt transport protein YP_001307056.1 1819254 R 391009 CDS YP_001307057.1 150021703 5297539 complement(1820001..1822139) 1 NC_009616.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 1822139 hppA 5297539 hppA Thermosipho melanesiensis BI429 membrane-bound proton-translocating pyrophosphatase YP_001307057.1 1820001 R 391009 CDS YP_001307058.1 150021704 5297540 1822288..1823007 1 NC_009616.1 PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator 1823007 5297540 Tmel_1838 Thermosipho melanesiensis BI429 two component transcriptional regulator YP_001307058.1 1822288 D 391009 CDS YP_001307059.1 150021705 5296773 1823011..1824282 1 NC_009616.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; PAS/PAC sensor signal transduction histidine kinase 1824282 5296773 Tmel_1839 Thermosipho melanesiensis BI429 PAS/PAC sensor signal transduction histidine kinase YP_001307059.1 1823011 D 391009 CDS YP_001307060.1 150021706 5296774 1824269..1825573 1 NC_009616.1 TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal domain; pyrimidine-nucleoside phosphorylase 1825573 5296774 Tmel_1840 Thermosipho melanesiensis BI429 pyrimidine-nucleoside phosphorylase YP_001307060.1 1824269 D 391009 CDS YP_001307061.1 150021707 5296635 1825583..1827187 1 NC_009616.1 hypothetical protein 1827187 5296635 Tmel_1841 Thermosipho melanesiensis BI429 hypothetical protein YP_001307061.1 1825583 D 391009 CDS YP_001307062.1 150021708 5296636 1827190..1827717 1 NC_009616.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1827717 5296636 Tmel_1842 Thermosipho melanesiensis BI429 adenine phosphoribosyltransferase YP_001307062.1 1827190 D 391009 CDS YP_001307063.1 150021709 5297905 1827731..1829083 1 NC_009616.1 catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate isomerase 1829083 5297905 Tmel_1843 Thermosipho melanesiensis BI429 glucose-6-phosphate isomerase YP_001307063.1 1827731 D 391009 CDS YP_001307064.1 150021710 5297906 1829083..1829298 1 NC_009616.1 hypothetical protein 1829298 5297906 Tmel_1844 Thermosipho melanesiensis BI429 hypothetical protein YP_001307064.1 1829083 D 391009 CDS YP_001307065.1 150021711 5297127 1829295..1829831 1 NC_009616.1 TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; dephospho-CoA kinase 1829831 5297127 Tmel_1845 Thermosipho melanesiensis BI429 dephospho-CoA kinase YP_001307065.1 1829295 D 391009 CDS YP_001307066.1 150021712 5297730 complement(1829847..1830659) 1 NC_009616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 1830659 5297730 Tmel_1846 Thermosipho melanesiensis BI429 diguanylate cyclase YP_001307066.1 1829847 R 391009 CDS YP_001307067.1 150021713 5297731 complement(1830699..1832687) 1 NC_009616.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1832687 5297731 Tmel_1847 Thermosipho melanesiensis BI429 excinuclease ABC subunit B YP_001307067.1 1830699 R 391009 CDS YP_001307068.1 150021714 5297873 complement(1832677..1834281) 1 NC_009616.1 PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; fibronectin-binding A domain-containing protein 1834281 5297873 Tmel_1848 Thermosipho melanesiensis BI429 fibronectin-binding A domain-containing protein YP_001307068.1 1832677 R 391009 CDS YP_001307069.1 150021715 5297874 complement(1834363..1836207) 1 NC_009616.1 PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 1836207 5297874 Tmel_1849 Thermosipho melanesiensis BI429 extracellular solute-binding protein YP_001307069.1 1834363 R 391009 CDS YP_001307070.1 150021716 5297627 complement(1836312..1836806) 1 NC_009616.1 hypothetical protein 1836806 5297627 Tmel_1850 Thermosipho melanesiensis BI429 hypothetical protein YP_001307070.1 1836312 R 391009 CDS YP_001307071.1 150021717 5297628 complement(1836824..1837105) 1 NC_009616.1 hypothetical protein 1837105 5297628 Tmel_1851 Thermosipho melanesiensis BI429 hypothetical protein YP_001307071.1 1836824 R 391009 CDS YP_001307072.1 150021718 5296962 complement(1837122..1837364) 1 NC_009616.1 hypothetical protein 1837364 5296962 Tmel_1852 Thermosipho melanesiensis BI429 hypothetical protein YP_001307072.1 1837122 R 391009 CDS YP_001307073.1 150021719 5296930 1837562..1838008 1 NC_009616.1 hypothetical protein 1838008 5296930 Tmel_1853 Thermosipho melanesiensis BI429 hypothetical protein YP_001307073.1 1837562 D 391009 CDS YP_001307074.1 150021720 5296656 1838005..1839282 1 NC_009616.1 PFAM: protein of unknown function DUF795; hypothetical protein 1839282 5296656 Tmel_1854 Thermosipho melanesiensis BI429 hypothetical protein YP_001307074.1 1838005 D 391009 CDS YP_001307075.1 150021721 5297528 1839275..1841980 1 NC_009616.1 PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; DEAD/DEAH box helicase domain-containing protein 1841980 5297528 Tmel_1855 Thermosipho melanesiensis BI429 DEAD/DEAH box helicase domain-containing protein YP_001307075.1 1839275 D 391009 CDS YP_001307076.1 150021722 5297124 complement(1842742..1843830) 1 NC_009616.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 1843830 5297124 Tmel_1857 Thermosipho melanesiensis BI429 DNA integrity scanning protein DisA YP_001307076.1 1842742 R 391009 CDS YP_001307077.1 150021723 5297916 complement(1843901..1844464) 1 NC_009616.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1844464 5297916 Tmel_1858 Thermosipho melanesiensis BI429 glutamine amidotransferase subunit PdxT YP_001307077.1 1843901 R 391009 CDS YP_001307078.1 150021724 5297917 complement(1844466..1845344) 1 NC_009616.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1845344 5297917 Tmel_1859 Thermosipho melanesiensis BI429 pyridoxal biosynthesis lyase PdxS YP_001307078.1 1844466 R 391009 CDS YP_001307079.1 150021725 5297983 complement(1845359..1847038) 1 NC_009616.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; methylmalonyl-CoA mutase, large subunit 1847038 5297983 Tmel_1860 Thermosipho melanesiensis BI429 methylmalonyl-CoA mutase, large subunit YP_001307079.1 1845359 R 391009 CDS YP_001307080.1 150021726 5297984 complement(1847073..1847711) 1 NC_009616.1 PFAM: class II aldolase/adducin family protein; class II aldolase/adducin family protein 1847711 5297984 Tmel_1861 Thermosipho melanesiensis BI429 class II aldolase/adducin family protein YP_001307080.1 1847073 R 391009 CDS YP_001307081.1 150021727 5297174 complement(1847708..1848010) 1 NC_009616.1 hypothetical protein 1848010 5297174 Tmel_1862 Thermosipho melanesiensis BI429 hypothetical protein YP_001307081.1 1847708 R 391009 CDS YP_001307082.1 150021728 5297175 complement(1847992..1848804) 1 NC_009616.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; holo-acyl-carrier-protein synthase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; 4'-phosphopantetheinyl transferase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1848804 5297175 Tmel_1863 Thermosipho melanesiensis BI429 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001307082.1 1847992 R 391009 CDS YP_001307083.1 150021729 5297343 complement(1848801..1850177) 1 NC_009616.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 1850177 5297343 Tmel_1864 Thermosipho melanesiensis BI429 oxaloacetate decarboxylase YP_001307083.1 1848801 R 391009 CDS YP_001307084.1 150021730 5297139 complement(1850182..1852260) 1 NC_009616.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1852260 infB 5297139 infB Thermosipho melanesiensis BI429 translation initiation factor IF-2 YP_001307084.1 1850182 R 391009 CDS YP_001307085.1 150021731 5297140 complement(1852282..1852482) 1 NC_009616.1 hypothetical protein 1852482 5297140 Tmel_1866 Thermosipho melanesiensis BI429 hypothetical protein YP_001307085.1 1852282 R 391009 CDS YP_001307086.1 150021732 5296685 complement(1852504..1853343) 1 NC_009616.1 PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 1853343 5296685 Tmel_1867 Thermosipho melanesiensis BI429 methyl-accepting chemotaxis sensory transducer YP_001307086.1 1852504 R 391009 CDS YP_001307087.1 150021733 5296686 complement(1853349..1854113) 1 NC_009616.1 PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1854113 5296686 Tmel_1868 Thermosipho melanesiensis BI429 beta-lactamase domain-containing protein YP_001307087.1 1853349 R 391009 CDS YP_001307088.1 150021734 5297414 1854282..1854911 1 NC_009616.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein 1854911 5297414 Tmel_1869 Thermosipho melanesiensis BI429 hypothetical protein YP_001307088.1 1854282 D 391009 CDS YP_001307089.1 150021735 5297415 1855236..1856252 1 NC_009616.1 PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; succinate--CoA ligase 1856252 5297415 Tmel_1870 Thermosipho melanesiensis BI429 succinate--CoA ligase YP_001307089.1 1855236 D 391009 CDS YP_001307090.1 150021736 5296629 1856249..1857091 1 NC_009616.1 PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; CoA-binding domain-containing protein 1857091 5296629 Tmel_1871 Thermosipho melanesiensis BI429 CoA-binding domain-containing protein YP_001307090.1 1856249 D 391009 CDS YP_001307091.1 150021737 5296630 1857095..1858225 1 NC_009616.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; YidE/YbjL duplication 1858225 5296630 Tmel_1872 Thermosipho melanesiensis BI429 YidE/YbjL duplication YP_001307091.1 1857095 D 391009 CDS YP_001307092.1 150021738 5296809 1858515..1859477 1 NC_009616.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; aspartate-semialdehyde dehydrogenase 1859477 5296809 Tmel_1873 Thermosipho melanesiensis BI429 aspartate-semialdehyde dehydrogenase YP_001307092.1 1858515 D 391009 CDS YP_001307093.1 150021739 5297262 1859470..1860168 1 NC_009616.1 PFAM: diaminopimelate epimerase; diaminopimelate epimerase 1860168 5297262 Tmel_1874 Thermosipho melanesiensis BI429 diaminopimelate epimerase YP_001307093.1 1859470 D 391009 CDS YP_001307094.1 150021740 5297263 1860161..1861027 1 NC_009616.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1861027 5297263 Tmel_1875 Thermosipho melanesiensis BI429 dihydrodipicolinate synthase YP_001307094.1 1860161 D 391009 CDS YP_001307095.1 150021741 5297475 1861024..1861677 1 NC_009616.1 PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 1861677 5297475 Tmel_1876 Thermosipho melanesiensis BI429 dihydrodipicolinate reductase YP_001307095.1 1861024 D 391009 CDS YP_001307096.1 150021742 5297476 1861674..1862369 1 NC_009616.1 PFAM: transferase hexapeptide repeat containing protein; Tetrahydrodipicolinate succinyltransferase N-terminal domain protein; tetrahydrodipicolinate succinyltransferase domain-containing protein 1862369 5297476 Tmel_1877 Thermosipho melanesiensis BI429 tetrahydrodipicolinate succinyltransferase domain-containing protein YP_001307096.1 1861674 D 391009 CDS YP_001307097.1 150021743 5297914 1862384..1863583 1 NC_009616.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1863583 5297914 Tmel_1878 Thermosipho melanesiensis BI429 aspartate kinase YP_001307097.1 1862384 D 391009 CDS YP_001307098.1 150021744 5297915 1863588..1864724 1 NC_009616.1 PFAM: aminotransferase class-III; class III aminotransferase 1864724 5297915 Tmel_1879 Thermosipho melanesiensis BI429 class III aminotransferase YP_001307098.1 1863588 D 391009 CDS YP_001307099.1 150021745 5296885 1865880..1866995 1 NC_009616.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1866995 5296885 Tmel_1881 Thermosipho melanesiensis BI429 DegT/DnrJ/EryC1/StrS aminotransferase YP_001307099.1 1865880 D 391009 CDS YP_001307100.1 150021746 5297407 1867008..1868474 1 NC_009616.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 1868474 5297407 Tmel_1882 Thermosipho melanesiensis BI429 apolipoprotein N-acyltransferase YP_001307100.1 1867008 D 391009 CDS YP_001307101.1 150021747 5297405 1868471..1869769 1 NC_009616.1 nicotinic acid phosphoribosyltransferase-like protein 1869769 5297405 Tmel_1883 Thermosipho melanesiensis BI429 nicotinic acid phosphoribosyltransferase-like protein YP_001307101.1 1868471 D 391009 CDS YP_001307102.1 150021748 5297570 1869872..1870081 1 NC_009616.1 hypothetical protein 1870081 5297570 Tmel_1884 Thermosipho melanesiensis BI429 hypothetical protein YP_001307102.1 1869872 D 391009 CDS YP_001307103.1 150021749 5297571 1870096..1871187 1 NC_009616.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1871187 gcvT 5297571 gcvT Thermosipho melanesiensis BI429 glycine cleavage system aminomethyltransferase T YP_001307103.1 1870096 D 391009 CDS YP_001307104.1 150021750 5297774 1871193..1872512 1 NC_009616.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1872512 5297774 Tmel_1886 Thermosipho melanesiensis BI429 glycine dehydrogenase subunit 1 YP_001307104.1 1871193 D 391009 CDS YP_001307105.1 150021751 5297775 1872528..1873973 1 NC_009616.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1873973 5297775 Tmel_1887 Thermosipho melanesiensis BI429 glycine dehydrogenase subunit 2 YP_001307105.1 1872528 D 391009 CDS YP_001307106.1 150021752 5296756 1873975..1875060 1 NC_009616.1 PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 1875060 5296756 Tmel_1888 Thermosipho melanesiensis BI429 iron-containing alcohol dehydrogenase YP_001307106.1 1873975 D 391009 CDS YP_001307107.1 150021753 5296757 1875057..1876223 1 NC_009616.1 PFAM: conserved hypothetical protein 95; SMART: PUA domain containing protein; hypothetical protein 1876223 5296757 Tmel_1889 Thermosipho melanesiensis BI429 hypothetical protein YP_001307107.1 1875057 D 391009 CDS YP_001307108.1 150021754 5297663 1876228..1877886 1 NC_009616.1 SMART: Pyrrolo-quinoline quinone; Pyrrolo-quinoline quinone 1877886 5297663 Tmel_1890 Thermosipho melanesiensis BI429 Pyrrolo-quinoline quinone YP_001307108.1 1876228 D 391009 CDS YP_001307109.1 150021755 5297664 1877888..1878427 1 NC_009616.1 PFAM: NUDIX hydrolase; NUDIX hydrolase 1878427 5297664 Tmel_1891 Thermosipho melanesiensis BI429 NUDIX hydrolase YP_001307109.1 1877888 D 391009 CDS YP_001307110.1 150021756 5297210 1878424..1879647 1 NC_009616.1 catalyzes the transamination of diaminopimelate with 2-oxoglutarate to produce tetrahydrodipicolinate and glutamate; diaminopimelate aminotransferase 1879647 5297210 Tmel_1892 Thermosipho melanesiensis BI429 diaminopimelate aminotransferase YP_001307110.1 1878424 D 391009 CDS YP_001307111.1 150021757 5297708 1879666..1881318 1 NC_009616.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1881318 5297708 Tmel_1893 Thermosipho melanesiensis BI429 urocanate hydratase YP_001307111.1 1879666 D 391009 CDS YP_001307112.1 150021758 5297387 complement(1882190..1882492) 1 NC_009616.1 PFAM: transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 1882492 5297387 Tmel_1895 Thermosipho melanesiensis BI429 transposase IS3/IS911 family protein YP_001307112.1 1882190 R 391009 CDS YP_001307113.1 150021759 5297471 complement(1882588..1883748) 1 NC_009616.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha 1883748 5297471 Tmel_1896 Thermosipho melanesiensis BI429 2-oxoglutarate ferredoxin oxidoreductase subunit alpha YP_001307113.1 1882588 R 391009 CDS YP_001307114.1 150021760 5297472 complement(1883741..1883968) 1 NC_009616.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 1883968 5297472 Tmel_1897 Thermosipho melanesiensis BI429 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_001307114.1 1883741 R 391009 CDS YP_001307115.1 150021761 5297765 complement(1883983..1885119) 1 NC_009616.1 TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; sodium ion-translocating decarboxylase subunit beta 1885119 5297765 Tmel_1898 Thermosipho melanesiensis BI429 sodium ion-translocating decarboxylase subunit beta YP_001307115.1 1883983 R 391009 CDS YP_001307116.1 150021762 5297766 complement(1885214..1885996) 1 NC_009616.1 DNA polymerase III gamma/tau subunits-like protein 1885996 5297766 Tmel_1899 Thermosipho melanesiensis BI429 DNA polymerase III gamma/tau subunits-like protein YP_001307116.1 1885214 R 391009 CDS YP_001307117.1 150021763 5297389 complement(1885989..1886621) 1 NC_009616.1 PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1886621 5297389 Tmel_1900 Thermosipho melanesiensis BI429 ABC transporter-like protein YP_001307117.1 1885989 R 391009 CDS YP_001307118.1 150021764 5297390 complement(1886663..1887421) 1 NC_009616.1 PFAM: protein of unknown function DUF62; hypothetical protein 1887421 5297390 Tmel_1901 Thermosipho melanesiensis BI429 hypothetical protein YP_001307118.1 1886663 R 391009 CDS YP_001307119.1 150021765 5297412 complement(1887431..1888438) 1 NC_009616.1 PFAM: phosphofructokinase; 6-phosphofructokinase 1888438 5297412 Tmel_1902 Thermosipho melanesiensis BI429 6-phosphofructokinase YP_001307119.1 1887431 R 391009 CDS YP_001307120.1 150021766 5297899 complement(1888440..1890389) 1 NC_009616.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 1890389 hppA 5297899 hppA Thermosipho melanesiensis BI429 membrane-bound proton-translocating pyrophosphatase YP_001307120.1 1888440 R 391009 CDS YP_001307121.1 150021767 5297900 complement(1890435..1891343) 1 NC_009616.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein; protein-export membrane protein SecF 1891343 5297900 Tmel_1904 Thermosipho melanesiensis BI429 protein-export membrane protein SecF YP_001307121.1 1890435 R 391009 CDS YP_001307122.1 150021768 5297537 complement(1891340..1892773) 1 NC_009616.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; protein-export membrane protein SecD 1892773 5297537 Tmel_1905 Thermosipho melanesiensis BI429 protein-export membrane protein SecD YP_001307122.1 1891340 R 391009 CDS YP_001307123.1 150021769 5297538 complement(1892792..1893142) 1 NC_009616.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; preprotein translocase subunit YajC 1893142 5297538 Tmel_1906 Thermosipho melanesiensis BI429 preprotein translocase subunit YajC YP_001307123.1 1892792 R 391009 CDS YP_001307124.1 150021770 5297046 complement(1893161..1893976) 1 NC_009616.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; tetrahydrofolate dehydrogenase/cyclohydrolase 1893976 5297046 Tmel_1907 Thermosipho melanesiensis BI429 tetrahydrofolate dehydrogenase/cyclohydrolase YP_001307124.1 1893161 R 391009 CDS YP_001307125.1 150021771 5297047 complement(1893989..1894339) 1 NC_009616.1 hypothetical protein 1894339 5297047 Tmel_1908 Thermosipho melanesiensis BI429 hypothetical protein YP_001307125.1 1893989 R 391009 CDS YP_001307126.1 150021772 5297546 complement(1894336..1895025) 1 NC_009616.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1895025 thyX 5297546 thyX Thermosipho melanesiensis BI429 FAD-dependent thymidylate synthase YP_001307126.1 1894336 R 391009 CDS YP_001307127.1 150021773 5297547 complement(1895015..1895665) 1 NC_009616.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1895665 rnhB 5297547 rnhB Thermosipho melanesiensis BI429 ribonuclease HII YP_001307127.1 1895015 R 391009 CDS YP_001307128.1 150021774 5297545 complement(1895662..1896138) 1 NC_009616.1 hypothetical protein 1896138 5297545 Tmel_1911 Thermosipho melanesiensis BI429 hypothetical protein YP_001307128.1 1895662 R 391009 CDS YP_001307129.1 150021775 5297897 complement(1896149..1897096) 1 NC_009616.1 hypothetical protein 1897096 5297897 Tmel_1912 Thermosipho melanesiensis BI429 hypothetical protein YP_001307129.1 1896149 R 391009 CDS YP_001307130.1 150021776 5297898 complement(1897117..1897821) 1 NC_009616.1 PFAM: Silent information regulator protein Sir2; silent information regulator protein Sir2 1897821 5297898 Tmel_1913 Thermosipho melanesiensis BI429 silent information regulator protein Sir2 YP_001307130.1 1897117 R 391009 CDS YP_001307131.1 150021777 5297665 complement(1897784..1898326) 1 NC_009616.1 PFAM: Chromate transporter; chromate transporter 1898326 5297665 Tmel_1914 Thermosipho melanesiensis BI429 chromate transporter YP_001307131.1 1897784 R 391009 CDS YP_001307132.1 150021778 5297666 complement(1898307..1898543) 1 NC_009616.1 hypothetical protein 1898543 5297666 Tmel_1915 Thermosipho melanesiensis BI429 hypothetical protein YP_001307132.1 1898307 R 391009 CDS YP_001307133.1 150021779 5297360 complement(1898548..1899984) 1 NC_009616.1 PFAM: Exonuclease VII, large subunit; exodeoxyribonuclease VII 1899984 5297360 Tmel_1916 Thermosipho melanesiensis BI429 exodeoxyribonuclease VII YP_001307133.1 1898548 R 391009 CDS YP_001307134.1 150021780 5297361 complement(1899984..1902656) 1 NC_009616.1 TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; DNA polymerase I 1902656 5297361 Tmel_1917 Thermosipho melanesiensis BI429 DNA polymerase I YP_001307134.1 1899984 R 391009 CDS YP_001307135.1 150021781 5297032 complement(1902634..1902999) 1 NC_009616.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; alkylhydroperoxidase 1902999 5297032 Tmel_1918 Thermosipho melanesiensis BI429 alkylhydroperoxidase YP_001307135.1 1902634 R 391009 CDS YP_001307136.1 150021782 5297033 complement(1903001..1905088) 1 NC_009616.1 PFAM: cell division protein FtsA; cell division protein FtsA 1905088 5297033 Tmel_1919 Thermosipho melanesiensis BI429 cell division protein FtsA YP_001307136.1 1903001 R 391009 CDS YP_001307137.1 150021783 5297504 complement(1905092..1907374) 1 NC_009616.1 TIGRFAM: MutS2 family protein; PFAM: DNA mismatch repair protein MutS domain protein; Smr protein/MutS2; SMART: AAA ATPase; MutS III domain protein; MutS2 family protein 1907374 5297504 Tmel_1920 Thermosipho melanesiensis BI429 MutS2 family protein YP_001307137.1 1905092 R 391009 CDS YP_001307138.1 150021784 5297920 complement(1907386..1908024) 1 NC_009616.1 hypothetical protein 1908024 5297920 Tmel_1921 Thermosipho melanesiensis BI429 hypothetical protein YP_001307138.1 1907386 R 391009 CDS YP_001307139.1 150021785 5297921 complement(1908074..1909267) 1 NC_009616.1 PFAM: phosphate transporter; phosphate transporter 1909267 5297921 Tmel_1922 Thermosipho melanesiensis BI429 phosphate transporter YP_001307139.1 1908074 R 391009 CDS YP_001307140.1 150021786 5297945 complement(1909285..1909956) 1 NC_009616.1 PFAM: protein of unknown function DUF47; hypothetical protein 1909956 5297945 Tmel_1923 Thermosipho melanesiensis BI429 hypothetical protein YP_001307140.1 1909285 R 391009 CDS YP_001307141.1 150021787 5297946 complement(1909958..1910929) 1 NC_009616.1 PFAM: conserved hypothetical protein 374; hypothetical protein 1910929 5297946 Tmel_1924 Thermosipho melanesiensis BI429 hypothetical protein YP_001307141.1 1909958 R 391009 CDS YP_001307142.1 150021788 5297656 complement(1910913..1911596) 1 NC_009616.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 1911596 5297656 Tmel_1925 Thermosipho melanesiensis BI429 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_001307142.1 1910913 R 391009 CDS YP_001307143.1 150021789 5297657 complement(1911606..1912463) 1 NC_009616.1 PFAM: helix-turn-helix, Fis-type; Fis family transcriptional regulator 1912463 5297657 Tmel_1926 Thermosipho melanesiensis BI429 Fis family transcriptional regulator YP_001307143.1 1911606 R 391009 CDS YP_001307144.1 150021790 5297842 complement(1912468..1913406) 1 NC_009616.1 this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable reaction at the extreme temperatures these organisms live under; carbamate kinase-like carbamoyl phosphate synthetase 1913406 5297842 Tmel_1927 Thermosipho melanesiensis BI429 carbamate kinase-like carbamoyl phosphate synthetase YP_001307144.1 1912468 R 391009 CDS YP_001307145.1 150021791 5297843 complement(1913403..1914305) 1 NC_009616.1 PFAM: phosphate acetyl/butaryl transferase; phosphate butyryltransferase 1914305 5297843 Tmel_1928 Thermosipho melanesiensis BI429 phosphate butyryltransferase YP_001307145.1 1913403 R 391009 CDS YP_001307146.1 150021792 5298459 complement(1914310..1915128) 1 NC_009616.1 PFAM: peptidase M55, D-aminopeptidase; peptidase M55, D-aminopeptidase 1915128 5298459 Tmel_1929 Thermosipho melanesiensis BI429 peptidase M55, D-aminopeptidase YP_001307146.1 1914310 R 391009 CDS