-- dump date 20111121_015345 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 391009000001 SEQ_END SEQ_END NC_009616.1 1915238 1915238 DR NC_009616.1; contig end 1915238..1915238 Thermosipho melanesiensis BI429 YP_001305268.1 CDS Tmel_0001 NC_009616.1 162 1475 D TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator, DnaA C-terminal domain; Chromosomal replication initiator, DnaA; SMART: AAA ATPase; chromosomal replication initiator protein DnaA 162..1475 Thermosipho melanesiensis BI429 5298195 YP_001305269.1 CDS Tmel_0002 NC_009616.1 1517 1699 D PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 1517..1699 Thermosipho melanesiensis BI429 5296486 YP_001305270.1 CDS Tmel_0005 NC_009616.1 5349 5702 R hypothetical protein complement(5349..5702) Thermosipho melanesiensis BI429 5298453 YP_001305271.1 CDS Tmel_0006 NC_009616.1 6140 6805 R hypothetical protein complement(6140..6805) Thermosipho melanesiensis BI429 5296579 YP_001305272.1 CDS Tmel_0007 NC_009616.1 6807 8114 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(6807..8114) Thermosipho melanesiensis BI429 5297534 YP_001305273.1 CDS Tmel_0008 NC_009616.1 8798 10666 R PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase/NADH oxidase complement(8798..10666) Thermosipho melanesiensis BI429 5297426 YP_001305274.1 CDS Tmel_0009 NC_009616.1 10663 10956 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(10663..10956) Thermosipho melanesiensis BI429 5297427 YP_001305275.1 CDS Tmel_0010 NC_009616.1 10975 11298 R PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein complement(10975..11298) Thermosipho melanesiensis BI429 5296742 YP_001305276.1 CDS Tmel_0011 NC_009616.1 11311 11655 R PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein complement(11311..11655) Thermosipho melanesiensis BI429 5296743 YP_001305277.1 CDS Tmel_0012 NC_009616.1 11672 12544 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase complement(11672..12544) Thermosipho melanesiensis BI429 5297834 YP_001305278.1 CDS Tmel_0013 NC_009616.1 12541 13389 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase complement(12541..13389) Thermosipho melanesiensis BI429 5296530 YP_001305279.1 CDS Tmel_0014 NC_009616.1 13589 15157 R TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; putative delta-1-pyrroline-5-carboxylate dehydrogenase complement(13589..15157) Thermosipho melanesiensis BI429 5296531 YP_001305280.1 CDS Tmel_0015 NC_009616.1 15352 17166 D hypothetical protein 15352..17166 Thermosipho melanesiensis BI429 5296850 YP_001305281.1 CDS Tmel_0016 NC_009616.1 17183 18280 D PFAM: basic membrane lipoprotein; basic membrane lipoprotein 17183..18280 Thermosipho melanesiensis BI429 5296851 YP_001305282.1 CDS Tmel_0017 NC_009616.1 18377 19900 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 18377..19900 Thermosipho melanesiensis BI429 5296525 YP_001305283.1 CDS Tmel_0018 NC_009616.1 19902 20936 D PFAM: inner-membrane translocator; inner-membrane translocator 19902..20936 Thermosipho melanesiensis BI429 5296735 YP_001305284.1 CDS Tmel_0019 NC_009616.1 20933 21892 D PFAM: inner-membrane translocator; inner-membrane translocator 20933..21892 Thermosipho melanesiensis BI429 5296736 YP_001305285.1 CDS Tmel_0020 NC_009616.1 21970 22107 D hypothetical protein 21970..22107 Thermosipho melanesiensis BI429 5297268 YP_001305286.1 CDS Tmel_0021 NC_009616.1 22599 23306 R TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein complement(22599..23306) Thermosipho melanesiensis BI429 5297830 YP_001305287.1 CDS Tmel_0022 NC_009616.1 23321 24187 R TIGRFAM: degV family protein; PFAM: DegV family protein; degV family protein complement(23321..24187) Thermosipho melanesiensis BI429 5297334 YP_001305288.1 CDS Tmel_0023 NC_009616.1 24177 25511 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(24177..25511) Thermosipho melanesiensis BI429 5297648 YP_001305289.1 CDS Tmel_0024 NC_009616.1 25504 27960 R PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase complement(25504..27960) Thermosipho melanesiensis BI429 5297649 YP_001305290.1 CDS Tmel_0025 NC_009616.1 28033 30261 R PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; phosphotransferase domain-containing protein complement(28033..30261) Thermosipho melanesiensis BI429 5297397 YP_001305291.1 CDS Tmel_0026 NC_009616.1 30360 30836 D TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 30360..30836 Thermosipho melanesiensis BI429 5297398 YP_001305292.1 CDS Tmel_0027 NC_009616.1 30930 31856 D PFAM: Mg2+ transporter protein, CorA family protein; Mg2+ transporter protein, CorA family protein 30930..31856 Thermosipho melanesiensis BI429 5296901 YP_001305293.1 CDS Tmel_0029 NC_009616.1 32947 33636 R hypothetical protein complement(32947..33636) Thermosipho melanesiensis BI429 5298292 YP_001305294.1 CDS Tmel_0030 NC_009616.1 33675 34613 R PFAM: Radical SAM domain protein; radical SAM domain-containing protein complement(33675..34613) Thermosipho melanesiensis BI429 5297160 YP_001305295.1 CDS Tmel_0031 NC_009616.1 34601 35395 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(34601..35395) Thermosipho melanesiensis BI429 5297023 YP_001305296.1 CDS Tmel_0032 NC_009616.1 35380 35934 R PFAM: isochorismatase hydrolase; isochorismatase hydrolase complement(35380..35934) Thermosipho melanesiensis BI429 5297024 YP_001305297.1 CDS Tmel_0033 NC_009616.1 35931 36821 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(35931..36821) Thermosipho melanesiensis BI429 5297421 YP_001305298.1 CDS Tmel_0034 NC_009616.1 36832 39153 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(36832..39153) Thermosipho melanesiensis BI429 5297103 YP_001305299.1 CDS Tmel_0035 NC_009616.1 39157 39834 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(39157..39834) Thermosipho melanesiensis BI429 5297104 YP_001305300.1 CDS Tmel_0036 NC_009616.1 39891 40502 D TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic region; thiamine pyrophosphokinase 39891..40502 Thermosipho melanesiensis BI429 5297164 YP_001305301.1 CDS Tmel_0037 NC_009616.1 40481 41539 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 40481..41539 Thermosipho melanesiensis BI429 5297165 YP_001305302.1 CDS Tmel_0038 NC_009616.1 41784 42665 D PFAM: periplasmic binding protein; periplasmic binding protein 41784..42665 Thermosipho melanesiensis BI429 5297052 YP_001305303.1 CDS Tmel_0039 NC_009616.1 42662 43633 D PFAM: transport system permease protein; ABC-3 protein; transport system permease 42662..43633 Thermosipho melanesiensis BI429 5297242 YP_001305304.1 CDS Tmel_0040 NC_009616.1 43659 44462 D TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase 43659..44462 Thermosipho melanesiensis BI429 5297243 YP_001305305.1 CDS Tmel_0041 NC_009616.1 44469 45089 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase factor sigma-70 44469..45089 Thermosipho melanesiensis BI429 5296873 YP_001305306.1 CDS Tmel_0042 NC_009616.1 45676 46128 R PFAM: 6,7-dimethyl-8-ribityllumazine synthase; riboflavin synthase complement(45676..46128) Thermosipho melanesiensis BI429 5298110 YP_001305307.1 CDS Tmel_0043 NC_009616.1 46125 47246 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein complement(46125..47246) Thermosipho melanesiensis BI429 5297102 YP_001305308.1 CDS Tmel_0044 NC_009616.1 47224 47790 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(47224..47790) Thermosipho melanesiensis BI429 5296785 YP_001305309.1 CDS Tmel_0045 NC_009616.1 47783 48796 R TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein; riboflavin biosynthesis protein RibD complement(47783..48796) Thermosipho melanesiensis BI429 5296786 YP_001305310.1 CDS Tmel_0046 NC_009616.1 48975 50666 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(48975..50666) Thermosipho melanesiensis BI429 5297532 YP_001305311.1 CDS Tmel_0047 NC_009616.1 50684 51091 R TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; NifU family SUF system FeS assembly protein complement(50684..51091) Thermosipho melanesiensis BI429 5297533 YP_001305312.1 CDS Tmel_0048 NC_009616.1 51081 52322 R TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase, class V; SufS subfamily cysteine desulfurase complement(51081..52322) Thermosipho melanesiensis BI429 5296507 YP_001305313.1 CDS Tmel_0049 NC_009616.1 52297 53415 R PFAM: SufBD protein; SufBD protein complement(52297..53415) Thermosipho melanesiensis BI429 5296758 YP_001305314.1 CDS Tmel_0050 NC_009616.1 53426 54817 R TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; FeS assembly protein SufB complement(53426..54817) Thermosipho melanesiensis BI429 5296759 YP_001305315.1 CDS Tmel_0051 NC_009616.1 54822 55565 R TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; FeS assembly ATPase SufC complement(54822..55565) Thermosipho melanesiensis BI429 5296547 YP_001305316.1 CDS groEL NC_009616.1 55681 57300 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(55681..57300) Thermosipho melanesiensis BI429 5296548 YP_001305317.1 CDS groES NC_009616.1 57317 57589 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(57317..57589) Thermosipho melanesiensis BI429 5297555 YP_001305318.1 CDS Tmel_0054 NC_009616.1 57948 58328 D PFAM: ribonuclease III; ribonuclease III 57948..58328 Thermosipho melanesiensis BI429 5298449 YP_001305319.1 CDS Tmel_0055 NC_009616.1 58325 60043 D hypothetical protein 58325..60043 Thermosipho melanesiensis BI429 5297758 YP_001305320.1 CDS Tmel_0056 NC_009616.1 60048 61436 D PFAM: peptidase U62, modulator of DNA gyrase; peptidase U62, modulator of DNA gyrase 60048..61436 Thermosipho melanesiensis BI429 5297044 YP_001305321.1 CDS Tmel_0057 NC_009616.1 61433 62740 D PFAM: peptidase U62, modulator of DNA gyrase; peptidase U62, modulator of DNA gyrase 61433..62740 Thermosipho melanesiensis BI429 5297045 YP_001305322.1 CDS Tmel_0058 NC_009616.1 62849 63910 D PFAM: alanine racemase domain protein; alanine racemase domain-containing protein 62849..63910 Thermosipho melanesiensis BI429 5297823 YP_001305323.1 CDS Tmel_0059 NC_009616.1 63937 65028 R hypothetical protein complement(63937..65028) Thermosipho melanesiensis BI429 5297824 YP_001305324.1 CDS queA NC_009616.1 65163 66167 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(65163..66167) Thermosipho melanesiensis BI429 5297825 YP_001305325.1 CDS Tmel_0061 NC_009616.1 66217 66471 R PFAM: ribosomal protein S15; ribosomal protein S15 complement(66217..66471) Thermosipho melanesiensis BI429 5297869 YP_001305326.1 CDS Tmel_0063 NC_009616.1 67257 68951 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(67257..68951) Thermosipho melanesiensis BI429 5298314 YP_001305327.1 CDS cysS NC_009616.1 68948 70357 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(68948..70357) Thermosipho melanesiensis BI429 5297951 YP_001305328.1 CDS gltX NC_009616.1 70362 71783 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(70362..71783) Thermosipho melanesiensis BI429 5296716 YP_001305329.1 CDS Tmel_0066 NC_009616.1 72024 73235 D TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; uracil-xanthine permease 72024..73235 Thermosipho melanesiensis BI429 5296717 YP_001305330.1 CDS Tmel_0068 NC_009616.1 73811 73936 R hypothetical protein complement(73811..73936) Thermosipho melanesiensis BI429 5298378 YP_001305331.1 CDS Tmel_0069 NC_009616.1 73936 74214 R hypothetical protein complement(73936..74214) Thermosipho melanesiensis BI429 5297375 YP_001305332.1 CDS Tmel_0070 NC_009616.1 74657 75685 R hypothetical protein complement(74657..75685) Thermosipho melanesiensis BI429 5296789 YP_001305333.1 CDS Tmel_0071 NC_009616.1 75769 77061 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 75769..77061 Thermosipho melanesiensis BI429 5296790 YP_001305334.1 CDS Tmel_0072 NC_009616.1 77080 77943 D PFAM: protein of unknown function DUF161; hypothetical protein 77080..77943 Thermosipho melanesiensis BI429 5296791 YP_001305335.1 CDS Tmel_0073 NC_009616.1 77953 78483 D PFAM: isochorismatase hydrolase; isochorismatase hydrolase 77953..78483 Thermosipho melanesiensis BI429 5296710 YP_001305336.1 CDS Tmel_0074 NC_009616.1 78485 79426 D TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; cation diffusion facilitator family transporter 78485..79426 Thermosipho melanesiensis BI429 5296711 YP_001305337.1 CDS Tmel_0075 NC_009616.1 79389 80480 D hypothetical protein 79389..80480 Thermosipho melanesiensis BI429 5297965 YP_001305338.1 CDS Tmel_0076 NC_009616.1 80501 81499 R TIGRFAM: galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase complement(80501..81499) Thermosipho melanesiensis BI429 5297296 YP_001305339.1 CDS Tmel_0077 NC_009616.1 81513 82958 R TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; glycogen/starch synthase complement(81513..82958) Thermosipho melanesiensis BI429 5297297 YP_001305340.1 CDS Tmel_0078 NC_009616.1 82964 83593 R PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein complement(82964..83593) Thermosipho melanesiensis BI429 5296926 YP_001305341.1 CDS Tmel_0079 NC_009616.1 83583 85277 R TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase; sigma-54 dependent trancsriptional regulator complement(83583..85277) Thermosipho melanesiensis BI429 5296927 YP_001305342.1 CDS Tmel_0080 NC_009616.1 85279 85689 R PFAM: protein of unknown function UPF0047; hypothetical protein complement(85279..85689) Thermosipho melanesiensis BI429 5297971 YP_001305343.1 CDS Tmel_0081 NC_009616.1 85686 86618 R PFAM: protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; D-alanine--D-alanine ligase complement(85686..86618) Thermosipho melanesiensis BI429 5297718 YP_001305344.1 CDS Tmel_0082 NC_009616.1 86615 88240 R PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein complement(86615..88240) Thermosipho melanesiensis BI429 5297719 YP_001305345.1 CDS Tmel_0083 NC_009616.1 88237 89316 R PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; NAD/NADP octopine/nopaline dehydrogenase complement(88237..89316) Thermosipho melanesiensis BI429 5297335 YP_001305346.1 CDS Tmel_0084 NC_009616.1 89330 90280 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(89330..90280) Thermosipho melanesiensis BI429 5297336 YP_001305347.1 CDS Tmel_0085 NC_009616.1 90286 91497 R PFAM: MOFRL domain protein; hydroxypyruvate reductase complement(90286..91497) Thermosipho melanesiensis BI429 5297383 YP_001305348.1 CDS Tmel_0086 NC_009616.1 91502 92341 R TIGRFAM: NAD+ synthetase; PFAM: NAD+ synthase; NAD+ synthetase complement(91502..92341) Thermosipho melanesiensis BI429 5297085 YP_001305349.1 CDS Tmel_0087 NC_009616.1 92325 93446 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(92325..93446) Thermosipho melanesiensis BI429 5297086 YP_001305350.1 CDS Tmel_0088 NC_009616.1 93451 94002 R PFAM: GrpE protein; GrpE protein complement(93451..94002) Thermosipho melanesiensis BI429 5297027 YP_001305351.1 CDS Tmel_0089 NC_009616.1 94018 95031 R TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein; heat-inducible transcription repressor HrcA complement(94018..95031) Thermosipho melanesiensis BI429 5297028 YP_001305352.1 CDS Tmel_0090 NC_009616.1 95135 96403 R PFAM: General substrate transporter; major facilitator superfamily MFS_1; major facilitator transporter complement(95135..96403) Thermosipho melanesiensis BI429 5297767 YP_001305353.1 CDS Tmel_0091 NC_009616.1 96403 96906 R PFAM: 3H domain protein; Helix-turn-helix, type 11 domain protein; 3H domain-containing protein complement(96403..96906) Thermosipho melanesiensis BI429 5296880 YP_001305354.1 CDS Tmel_0092 NC_009616.1 97024 97653 R TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; hemolysin III family channel protein complement(97024..97653) Thermosipho melanesiensis BI429 5296881 YP_001305355.1 CDS Tmel_0093 NC_009616.1 97650 98069 R PFAM: peptidylprolyl isomerase, FKBP-type; FKBP-type peptidylprolyl isomerase complement(97650..98069) Thermosipho melanesiensis BI429 5297932 YP_001305356.1 CDS Tmel_0094 NC_009616.1 98443 99663 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(98443..99663) Thermosipho melanesiensis BI429 5297933 YP_001305357.1 CDS Tmel_0095 NC_009616.1 99647 100597 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(99647..100597) Thermosipho melanesiensis BI429 5297973 YP_001305358.1 CDS Tmel_0096 NC_009616.1 100684 101703 D PFAM: peptidase M18, aminopeptidase I; peptidase M20; peptidase M42 family protein; peptidase M42 family protein 100684..101703 Thermosipho melanesiensis BI429 5297357 YP_001305359.1 CDS Tmel_0097 NC_009616.1 101703 102707 D PFAM: peptidase M42 family protein; cellulase 101703..102707 Thermosipho melanesiensis BI429 5297358 YP_001305360.1 CDS Tmel_0098 NC_009616.1 102732 102959 R TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; DNA-directed RNA polymerase subunit omega complement(102732..102959) Thermosipho melanesiensis BI429 5296487 YP_001305361.1 CDS gmk NC_009616.1 102961 103575 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(102961..103575) Thermosipho melanesiensis BI429 5296488 YP_001305362.1 CDS Tmel_0100 NC_009616.1 103577 103861 R PFAM: protein of unknown function DUF370; hypothetical protein complement(103577..103861) Thermosipho melanesiensis BI429 5297144 YP_001305363.1 CDS Tmel_0101 NC_009616.1 103880 104752 R PFAM: YicC N-terminal domain protein; hypothetical protein complement(103880..104752) Thermosipho melanesiensis BI429 5296694 YP_001305364.1 CDS Tmel_0102 NC_009616.1 104889 105425 R PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate ferredoxin/flavodoxin oxidoreductase complement(104889..105425) Thermosipho melanesiensis BI429 5296695 YP_001305365.1 CDS Tmel_0103 NC_009616.1 105422 106174 R PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein complement(105422..106174) Thermosipho melanesiensis BI429 5296847 YP_001305366.1 CDS Tmel_0104 NC_009616.1 106180 107238 R catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase complement(106180..107238) Thermosipho melanesiensis BI429 5296848 YP_001305367.1 CDS Tmel_0105 NC_009616.1 107251 107472 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(107251..107472) Thermosipho melanesiensis BI429 5296518 YP_001305368.1 CDS Tmel_0106 NC_009616.1 107486 108130 R hypothetical protein complement(107486..108130) Thermosipho melanesiensis BI429 5297294 YP_001305369.1 CDS Tmel_0107 NC_009616.1 108123 109214 R catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase complement(108123..109214) Thermosipho melanesiensis BI429 5297295 YP_001305370.1 CDS Tmel_0108 NC_009616.1 109207 110118 R PFAM: phosphate acetyl/butaryl transferase; phosphate butyryltransferase complement(109207..110118) Thermosipho melanesiensis BI429 5296990 YP_001305371.1 CDS Tmel_0109 NC_009616.1 110102 111172 R catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase complement(110102..111172) Thermosipho melanesiensis BI429 5296991 YP_001305372.1 CDS Tmel_0110 NC_009616.1 111172 112407 R PFAM: aminotransferase, class I and II; GntR family transcriptional regulator complement(111172..112407) Thermosipho melanesiensis BI429 5297626 YP_001305373.1 CDS Tmel_0111 NC_009616.1 112674 113816 D PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; class V aminotransferase 112674..113816 Thermosipho melanesiensis BI429 5296514 YP_001305374.1 CDS Tmel_0112 NC_009616.1 113816 114727 D PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; phosphoglycerate dehydrogenase 113816..114727 Thermosipho melanesiensis BI429 5296515 YP_001305375.1 CDS Tmel_0113 NC_009616.1 114774 116468 R PFAM: carbon starvation protein CstA; carbon starvation protein CstA complement(114774..116468) Thermosipho melanesiensis BI429 5297329 YP_001305376.1 CDS Tmel_0114 NC_009616.1 116610 117290 R PFAM: response regulator receiver; LytTr DNA-binding region; LytTR family two component transcriptional regulator complement(116610..117290) Thermosipho melanesiensis BI429 5297330 YP_001305377.1 CDS Tmel_0115 NC_009616.1 117287 118945 R PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; signal transduction histidine kinase LytS complement(117287..118945) Thermosipho melanesiensis BI429 5296944 YP_001305378.1 CDS Tmel_0116 NC_009616.1 118939 119217 R hypothetical protein complement(118939..119217) Thermosipho melanesiensis BI429 5297203 YP_001305379.1 CDS Tmel_0117 NC_009616.1 119761 120966 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 119761..120966 Thermosipho melanesiensis BI429 5298379 YP_001305380.1 CDS Tmel_0118 NC_009616.1 120969 121958 D PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase carbamoyl phosphate-binding subunit 120969..121958 Thermosipho melanesiensis BI429 5296519 YP_001305381.1 CDS Tmel_0119 NC_009616.1 121959 123251 D PFAM: amidohydrolase; dihydropyrimidinase 121959..123251 Thermosipho melanesiensis BI429 5296520 YP_001305382.1 CDS Tmel_0120 NC_009616.1 123251 124531 D PFAM: amidohydrolase; amidohydrolase 123251..124531 Thermosipho melanesiensis BI429 5296554 YP_001305383.1 CDS Tmel_0121 NC_009616.1 124544 125626 D TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; dihydroorotate dehydrogenase family protein 124544..125626 Thermosipho melanesiensis BI429 5297847 YP_001305384.1 CDS Tmel_0122 NC_009616.1 126232 126495 D PFAM: Stage V sporulation protein S; stage V sporulation protein S 126232..126495 Thermosipho melanesiensis BI429 5297995 YP_001305385.1 CDS ushA NC_009616.1 126544 128091 R catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic complement(126544..128091) Thermosipho melanesiensis BI429 5296552 YP_001305386.1 CDS Tmel_0124 NC_009616.1 128131 129852 R PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(128131..129852) Thermosipho melanesiensis BI429 5296553 YP_001305387.1 CDS Tmel_0125 NC_009616.1 129858 132002 R hypothetical protein complement(129858..132002) Thermosipho melanesiensis BI429 5297460 YP_001305388.1 CDS Tmel_0126 NC_009616.1 132013 132627 R hypothetical protein complement(132013..132627) Thermosipho melanesiensis BI429 5297230 YP_001305389.1 CDS Tmel_0127 NC_009616.1 132635 135001 R hypothetical protein complement(132635..135001) Thermosipho melanesiensis BI429 5297231 YP_001305390.1 CDS Tmel_0128 NC_009616.1 135001 135528 R PFAM: protein of unknown function DUF151; hypothetical protein complement(135001..135528) Thermosipho melanesiensis BI429 5297942 YP_001305391.1 CDS Tmel_0129 NC_009616.1 135515 136270 R TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(135515..136270) Thermosipho melanesiensis BI429 5297943 YP_001305392.1 CDS Tmel_0130 NC_009616.1 136267 137436 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(136267..137436) Thermosipho melanesiensis BI429 5297647 YP_001305393.1 CDS Tmel_0131 NC_009616.1 137473 137745 R PFAM: protein of unknown function DUF156; hypothetical protein complement(137473..137745) Thermosipho melanesiensis BI429 5296667 YP_001305394.1 CDS Tmel_0132 NC_009616.1 138743 139270 D PFAM: NLP/P60 protein; NLP/P60 protein 138743..139270 Thermosipho melanesiensis BI429 5296668 YP_001305395.1 CDS Tmel_0133 NC_009616.1 139504 141345 R PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter transmembrane region complement(139504..141345) Thermosipho melanesiensis BI429 5297337 YP_001305396.1 CDS Tmel_0134 NC_009616.1 141342 143066 R PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(141342..143066) Thermosipho melanesiensis BI429 5297338 YP_001305397.1 CDS Tmel_0135 NC_009616.1 143050 143499 R PFAM: regulatory protein, MarR; MarR family transcriptional regulator complement(143050..143499) Thermosipho melanesiensis BI429 5297968 YP_001305398.1 CDS Tmel_0136 NC_009616.1 143605 147528 D PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain-containing protein 143605..147528 Thermosipho melanesiensis BI429 5296482 YP_001305399.1 CDS Tmel_0137 NC_009616.1 147590 147949 D hypothetical protein 147590..147949 Thermosipho melanesiensis BI429 5296483 YP_001305400.1 CDS Tmel_0138 NC_009616.1 147906 148529 D PFAM: protein of unknown function DUF1175; hypothetical protein 147906..148529 Thermosipho melanesiensis BI429 5297118 YP_001305401.1 CDS Tmel_0139 NC_009616.1 148571 149785 R PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(148571..149785) Thermosipho melanesiensis BI429 5297119 YP_001305402.1 CDS Tmel_0140 NC_009616.1 149930 150448 D hypothetical protein 149930..150448 Thermosipho melanesiensis BI429 5297959 YP_001305403.1 CDS Tmel_0141 NC_009616.1 150467 151801 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(150467..151801) Thermosipho melanesiensis BI429 5296730 YP_001305404.1 CDS Tmel_0142 NC_009616.1 151944 153473 R PFAM: Abortive infection protein; abortive infection protein complement(151944..153473) Thermosipho melanesiensis BI429 5296731 YP_001305405.1 CDS Tmel_0143 NC_009616.1 153522 153917 R hypothetical protein complement(153522..153917) Thermosipho melanesiensis BI429 5297889 YP_001305406.1 CDS Tmel_0144 NC_009616.1 154175 155788 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(154175..155788) Thermosipho melanesiensis BI429 5297890 YP_001305407.1 CDS Tmel_0145 NC_009616.1 155939 156235 R hypothetical protein complement(155939..156235) Thermosipho melanesiensis BI429 5297388 YP_001305408.1 CDS Tmel_0146 NC_009616.1 156237 157946 R TIGRFAM: oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; M3 family oligoendopeptidase complement(156237..157946) Thermosipho melanesiensis BI429 5297087 YP_001305409.1 CDS Tmel_0147 NC_009616.1 157930 159318 R TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; MATE efflux family protein complement(157930..159318) Thermosipho melanesiensis BI429 5297088 YP_001305410.1 CDS Tmel_0148 NC_009616.1 159437 160396 D PFAM: aldo/keto reductase; aldo/keto reductase 159437..160396 Thermosipho melanesiensis BI429 5296503 YP_001305411.1 CDS Tmel_0149 NC_009616.1 160398 161594 D PFAM: peptidase M29, aminopeptidase II; peptidase M29, aminopeptidase II 160398..161594 Thermosipho melanesiensis BI429 5296504 YP_001305412.1 CDS Tmel_0150 NC_009616.1 161580 162596 R PFAM: ABC-2 type transporter; ABC-2 type transporter complement(161580..162596) Thermosipho melanesiensis BI429 5297802 YP_001305413.1 CDS Tmel_0151 NC_009616.1 162598 163449 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(162598..163449) Thermosipho melanesiensis BI429 5297794 YP_001305414.1 CDS Tmel_0152 NC_009616.1 163446 164423 R PFAM: ABC-2 type transporter; ABC-2 type transporter complement(163446..164423) Thermosipho melanesiensis BI429 5297795 YP_001305415.1 CDS Tmel_0153 NC_009616.1 164416 164955 R PFAM: Appr-1-p processing domain protein; appr-1-p processing domain-containing protein complement(164416..164955) Thermosipho melanesiensis BI429 5297432 YP_001305416.1 CDS Tmel_0154 NC_009616.1 164939 166171 R PFAM: AAA ATPase, central domain protein; recombination factor protein RarA complement(164939..166171) Thermosipho melanesiensis BI429 5297433 YP_001305417.1 CDS Tmel_0155 NC_009616.1 166140 167072 R PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; NAD-dependent epimerase/dehydratase complement(166140..167072) Thermosipho melanesiensis BI429 5297954 YP_001305418.1 CDS Tmel_0156 NC_009616.1 167072 167575 R PFAM: iron dependent repressor; iron dependent repressor complement(167072..167575) Thermosipho melanesiensis BI429 5297008 YP_001305419.1 CDS Tmel_0157 NC_009616.1 167565 168167 R TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; phage SPO1 DNA polymerase-like protein complement(167565..168167) Thermosipho melanesiensis BI429 5297009 YP_001305420.1 CDS Tmel_0158 NC_009616.1 168369 171014 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 168369..171014 Thermosipho melanesiensis BI429 5297813 YP_001305421.1 CDS Tmel_0159 NC_009616.1 171072 171482 D hypothetical protein 171072..171482 Thermosipho melanesiensis BI429 5297814 YP_001305422.1 CDS glmU NC_009616.1 171479 172831 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 171479..172831 Thermosipho melanesiensis BI429 5296987 YP_001305423.1 CDS Tmel_0161 NC_009616.1 172812 173762 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 172812..173762 Thermosipho melanesiensis BI429 5296687 YP_001305424.1 CDS Tmel_0162 NC_009616.1 173797 174447 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 173797..174447 Thermosipho melanesiensis BI429 5296688 YP_001305425.1 CDS Tmel_0163 NC_009616.1 174509 174985 D PFAM: peptidyl-tRNA hydrolase; aminoacyl-tRNA hydrolase 174509..174985 Thermosipho melanesiensis BI429 5297686 YP_001305426.1 CDS Tmel_0164 NC_009616.1 174982 175407 D hypothetical protein 174982..175407 Thermosipho melanesiensis BI429 5297687 YP_001305427.1 CDS Tmel_0165 NC_009616.1 175448 177007 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 175448..177007 Thermosipho melanesiensis BI429 5297384 YP_001305428.1 CDS Tmel_0166 NC_009616.1 177021 178181 D hypothetical protein 177021..178181 Thermosipho melanesiensis BI429 5297255 YP_001305429.1 CDS Tmel_0167 NC_009616.1 178174 178620 D adenylylsulfate kinase-like kinase 178174..178620 Thermosipho melanesiensis BI429 5297256 YP_001305430.1 CDS uvrA NC_009616.1 178621 181386 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 178621..181386 Thermosipho melanesiensis BI429 5297962 YP_001305431.1 CDS Tmel_0169 NC_009616.1 181388 182236 D PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; phage integrase family protein 181388..182236 Thermosipho melanesiensis BI429 5297963 YP_001305432.1 CDS Tmel_0170 NC_009616.1 182498 182659 R hypothetical protein complement(182498..182659) Thermosipho melanesiensis BI429 5297574 YP_001305433.1 CDS Tmel_0171 NC_009616.1 183092 183676 D hypothetical protein 183092..183676 Thermosipho melanesiensis BI429 5297090 YP_001305434.1 CDS Tmel_0172 NC_009616.1 183772 184362 D hypothetical protein 183772..184362 Thermosipho melanesiensis BI429 5297091 YP_001305435.1 CDS Tmel_0173 NC_009616.1 184424 185053 D hypothetical protein 184424..185053 Thermosipho melanesiensis BI429 5297634 YP_001305436.1 CDS eno NC_009616.1 185185 186474 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(185185..186474) Thermosipho melanesiensis BI429 5297635 YP_001305437.1 CDS Tmel_0175 NC_009616.1 186600 187805 R hypothetical protein complement(186600..187805) Thermosipho melanesiensis BI429 5298296 YP_001305438.1 CDS Tmel_0176 NC_009616.1 187844 188875 R PFAM: S-layer domain protein domain protein; S-layer domain-containing protein complement(187844..188875) Thermosipho melanesiensis BI429 5298309 YP_001305439.1 CDS Tmel_0177 NC_009616.1 188976 190172 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(188976..190172) Thermosipho melanesiensis BI429 5298310 YP_001305440.1 CDS Tmel_0178 NC_009616.1 190184 190414 R TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; preprotein translocase subunit SecG complement(190184..190414) Thermosipho melanesiensis BI429 5298160 YP_001305441.1 CDS Tmel_0179 NC_009616.1 190473 192248 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(190473..192248) Thermosipho melanesiensis BI429 5298161 YP_001305442.1 CDS Tmel_0180 NC_009616.1 192261 193283 R PFAM: putative RNA methylase; putative RNA methylase complement(192261..193283) Thermosipho melanesiensis BI429 5298123 YP_001305443.1 CDS Tmel_0181 NC_009616.1 193280 193597 R PFAM: protein of unknown function DUF190; hypothetical protein complement(193280..193597) Thermosipho melanesiensis BI429 5298005 YP_001305444.1 CDS Tmel_0182 NC_009616.1 193594 193971 R TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; CrcB protein complement(193594..193971) Thermosipho melanesiensis BI429 5298006 YP_001305445.1 CDS Tmel_0183 NC_009616.1 193968 194444 R hypothetical protein complement(193968..194444) Thermosipho melanesiensis BI429 5298156 YP_001305446.1 CDS Tmel_0184 NC_009616.1 194441 195016 R TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase complement(194441..195016) Thermosipho melanesiensis BI429 5298157 YP_001305447.1 CDS Tmel_0185 NC_009616.1 195027 195485 R PFAM: protein of unknown function DUF163; hypothetical protein complement(195027..195485) Thermosipho melanesiensis BI429 5298068 YP_001305448.1 CDS Tmel_0186 NC_009616.1 195482 196009 R PFAM: protein of unknown function DUF501; hypothetical protein complement(195482..196009) Thermosipho melanesiensis BI429 5298447 YP_001305449.1 CDS Tmel_0187 NC_009616.1 195982 196758 R PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; conserved hypothetical protein 95; methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; ribosomal L11 methyltransferase complement(195982..196758) Thermosipho melanesiensis BI429 5298448 YP_001305450.1 CDS Tmel_0188 NC_009616.1 196759 197574 R PFAM: Peptidoglycan-binding LysM; peptidase M23B; peptidase M23B complement(196759..197574) Thermosipho melanesiensis BI429 5298407 YP_001305451.1 CDS Tmel_0189 NC_009616.1 197806 198186 D hypothetical protein 197806..198186 Thermosipho melanesiensis BI429 5298408 YP_001305452.1 CDS Tmel_0190 NC_009616.1 198192 199010 D PFAM: protein of unknown function DUF849; hypothetical protein 198192..199010 Thermosipho melanesiensis BI429 5298388 YP_001305453.1 CDS Tmel_0191 NC_009616.1 199015 200046 D hypothetical protein 199015..200046 Thermosipho melanesiensis BI429 5298354 YP_001305454.1 CDS Tmel_0192 NC_009616.1 200059 201330 D TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 200059..201330 Thermosipho melanesiensis BI429 5298355 YP_001305455.1 CDS Tmel_0193 NC_009616.1 201327 201737 D PFAM: MaoC domain protein dehydratase; dehydratase 201327..201737 Thermosipho melanesiensis BI429 5298275 YP_001305456.1 CDS Tmel_0194 NC_009616.1 201695 202705 D hypothetical protein 201695..202705 Thermosipho melanesiensis BI429 5298276 YP_001305457.1 CDS Tmel_0195 NC_009616.1 202689 204029 D PFAM: DNA mismatch repair protein MutS domain protein; DNA mismatch repair protein MutS domain-containing protein 202689..204029 Thermosipho melanesiensis BI429 5298389 YP_001305458.1 CDS Tmel_0196 NC_009616.1 204019 205581 D PFAM: D-Lysine 5,6-aminomutase alpha subunit; D-lysine 5,6-aminomutase alpha subunit 204019..205581 Thermosipho melanesiensis BI429 5298189 YP_001305459.1 CDS Tmel_0197 NC_009616.1 205578 206363 D PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 205578..206363 Thermosipho melanesiensis BI429 5298190 YP_001305460.1 CDS Tmel_0198 NC_009616.1 206369 207511 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(206369..207511) Thermosipho melanesiensis BI429 5297998 YP_001305461.1 CDS Tmel_0199 NC_009616.1 207520 208146 R TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein complement(207520..208146) Thermosipho melanesiensis BI429 5297999 YP_001305462.1 CDS Tmel_0200 NC_009616.1 208149 208541 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(208149..208541) Thermosipho melanesiensis BI429 5298158 YP_001305463.1 CDS Tmel_0204 NC_009616.1 211151 212509 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(211151..212509) Thermosipho melanesiensis BI429 5298412 YP_001305464.1 CDS Tmel_0205 NC_009616.1 212493 212873 R thioesterase-like protein complement(212493..212873) Thermosipho melanesiensis BI429 5298267 YP_001305465.1 CDS Tmel_0206 NC_009616.1 212851 214704 R TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATP-dependent metalloprotease FtsH complement(212851..214704) Thermosipho melanesiensis BI429 5298144 YP_001305466.1 CDS Tmel_0207 NC_009616.1 214701 215972 R TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; tRNA(Ile)-lysidine synthetase complement(214701..215972) Thermosipho melanesiensis BI429 5298145 YP_001305467.1 CDS Tmel_0208 NC_009616.1 216055 217059 D PFAM: peptidase M20; peptidase M42 family protein; peptidase M42 family protein 216055..217059 Thermosipho melanesiensis BI429 5298304 YP_001305468.1 CDS Tmel_0209 NC_009616.1 217043 217741 D hypothetical protein 217043..217741 Thermosipho melanesiensis BI429 5298417 YP_001305469.1 CDS Tmel_0210 NC_009616.1 217753 218505 D PFAM: Bacitracin resistance protein BacA; bacitracin resistance protein BacA 217753..218505 Thermosipho melanesiensis BI429 5298418 YP_001305470.1 CDS Tmel_0211 NC_009616.1 218502 219698 D TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; imidazolonepropionase 218502..219698 Thermosipho melanesiensis BI429 5298335 YP_001305471.1 CDS Tmel_0212 NC_009616.1 219685 220023 D PFAM: protein of unknown function DUF1312; hypothetical protein 219685..220023 Thermosipho melanesiensis BI429 5298336 YP_001305472.1 CDS Tmel_0213 NC_009616.1 220017 220502 D PFAM: Heptaprenyl diphosphate synthase component I; heptaprenyl diphosphate synthase component I 220017..220502 Thermosipho melanesiensis BI429 5298237 YP_001305473.1 CDS Tmel_0214 NC_009616.1 220480 221028 D TIGRFAM: maf protein; PFAM: Maf family protein; maf protein 220480..221028 Thermosipho melanesiensis BI429 5298442 YP_001305474.1 CDS Tmel_0215 NC_009616.1 221029 221670 D PFAM: helix-hairpin-helix motif; DNA repair protein RadC; DNA repair protein RadC 221029..221670 Thermosipho melanesiensis BI429 5298443 YP_001305475.1 CDS Tmel_0216 NC_009616.1 221682 222827 D hypothetical protein 221682..222827 Thermosipho melanesiensis BI429 5298430 YP_001305476.1 CDS Tmel_0217 NC_009616.1 222829 224235 D hypothetical protein 222829..224235 Thermosipho melanesiensis BI429 5298431 YP_001305477.1 CDS Tmel_0218 NC_009616.1 224232 225371 D PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 224232..225371 Thermosipho melanesiensis BI429 5298384 YP_001305478.1 CDS Tmel_0219 NC_009616.1 225382 226125 D PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 225382..226125 Thermosipho melanesiensis BI429 5298382 YP_001305479.1 CDS Tmel_0220 NC_009616.1 226109 227110 D hypothetical protein 226109..227110 Thermosipho melanesiensis BI429 5298383 YP_001305480.1 CDS Tmel_0221 NC_009616.1 227107 229422 R RND efflux transporter complement(227107..229422) Thermosipho melanesiensis BI429 5298347 YP_001305481.1 CDS Tmel_0222 NC_009616.1 229424 229816 R hypothetical protein complement(229424..229816) Thermosipho melanesiensis BI429 5298348 YP_001305482.1 CDS Tmel_0223 NC_009616.1 229809 230327 R hypothetical protein complement(229809..230327) Thermosipho melanesiensis BI429 5298345 YP_001305483.1 CDS Tmel_0224 NC_009616.1 230324 231529 R TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; carboxyl-terminal protease complement(230324..231529) Thermosipho melanesiensis BI429 5298301 YP_001305484.1 CDS Tmel_0225 NC_009616.1 231522 232313 R PFAM: Methyltransferase type 11; tRNA methyltransferase complex GCD14 subunit; tRNA methyltransferase complex GCD14 subunit complement(231522..232313) Thermosipho melanesiensis BI429 5298302 YP_001305485.1 CDS Tmel_0226 NC_009616.1 232327 232743 R hypothetical protein complement(232327..232743) Thermosipho melanesiensis BI429 5298285 YP_001305486.1 CDS Tmel_0227 NC_009616.1 232747 233433 R hypothetical protein complement(232747..233433) Thermosipho melanesiensis BI429 5298286 YP_001305487.1 CDS Tmel_0228 NC_009616.1 233430 234020 R PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase complement(233430..234020) Thermosipho melanesiensis BI429 5297986 YP_001305488.1 CDS Tmel_0229 NC_009616.1 234017 234295 R PFAM: protein of unknown function DUF503; hypothetical protein complement(234017..234295) Thermosipho melanesiensis BI429 5298422 YP_001305489.1 CDS Tmel_0230 NC_009616.1 234297 234827 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(234297..234827) Thermosipho melanesiensis BI429 5298423 YP_001305490.1 CDS Tmel_0231 NC_009616.1 234824 235831 R TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC, N-terminal domain; Sua5/YciO/YrdC/YwlC family protein complement(234824..235831) Thermosipho melanesiensis BI429 5298081 YP_001305491.1 CDS Tmel_0232 NC_009616.1 235821 236669 R PFAM: phospholipase D/Transphosphatidylase; phospholipase D/transphosphatidylase complement(235821..236669) Thermosipho melanesiensis BI429 5298082 YP_001305492.1 CDS Tmel_0233 NC_009616.1 236656 238467 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(236656..238467) Thermosipho melanesiensis BI429 5298035 YP_001305493.1 CDS Tmel_0234 NC_009616.1 238454 239734 R TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramoylalanine--D-glutamate ligase complement(238454..239734) Thermosipho melanesiensis BI429 5298187 YP_001305494.1 CDS Tmel_0235 NC_009616.1 239752 241041 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(239752..241041) Thermosipho melanesiensis BI429 5298188 YP_001305495.1 CDS Tmel_0236 NC_009616.1 241031 241942 R TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; methionyl-tRNA formyltransferase complement(241031..241942) Thermosipho melanesiensis BI429 5298152 YP_001305496.1 CDS Tmel_0237 NC_009616.1 241973 242749 R TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; dimethyladenosine transferase complement(241973..242749) Thermosipho melanesiensis BI429 5298153 YP_001305497.1 CDS Tmel_0238 NC_009616.1 242746 243345 R hypothetical protein complement(242746..243345) Thermosipho melanesiensis BI429 5298359 YP_001305498.1 CDS Tmel_0239 NC_009616.1 243357 244352 R PFAM: MECDP-synthase; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(243357..244352) Thermosipho melanesiensis BI429 5298132 YP_001305499.1 CDS Tmel_0240 NC_009616.1 244362 245354 R hypothetical protein complement(244362..245354) Thermosipho melanesiensis BI429 5298133 YP_001305500.1 CDS glgC NC_009616.1 245366 246604 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(245366..246604) Thermosipho melanesiensis BI429 5298167 YP_001305501.1 CDS Tmel_0242 NC_009616.1 246616 247731 R TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; glucose-1-phosphate adenylyltransferase, GlgD subunit complement(246616..247731) Thermosipho melanesiensis BI429 5298168 YP_001305502.1 CDS Tmel_0243 NC_009616.1 247740 248465 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(247740..248465) Thermosipho melanesiensis BI429 5298470 YP_001305503.1 CDS smpB NC_009616.1 248462 248905 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(248462..248905) Thermosipho melanesiensis BI429 5296871 YP_001305504.1 CDS Tmel_0245 NC_009616.1 248916 249197 R TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; glutamyl-tRNA(Gln) amidotransferase subunit C complement(248916..249197) Thermosipho melanesiensis BI429 5296872 YP_001305505.1 CDS Tmel_0246 NC_009616.1 249184 249411 R PFAM: carbon storage regulator; carbon storage regulator CsrA complement(249184..249411) Thermosipho melanesiensis BI429 5296997 YP_001305506.1 CDS Tmel_0247 NC_009616.1 249421 249849 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW complement(249421..249849) Thermosipho melanesiensis BI429 5296998 YP_001305507.1 CDS Tmel_0248 NC_009616.1 249858 250622 R PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(249858..250622) Thermosipho melanesiensis BI429 5296860 YP_001305508.1 CDS Tmel_0249 NC_009616.1 250624 251022 R PFAM: Positive regulator of sigma(E), RseC/MucC; positive regulator of sigma E, RseC/MucC complement(250624..251022) Thermosipho melanesiensis BI429 5297395 YP_001305509.1 CDS Tmel_0250 NC_009616.1 251031 252644 R PFAM: Dak phosphatase; Dak phosphatase complement(251031..252644) Thermosipho melanesiensis BI429 5297396 YP_001305510.1 CDS Tmel_0251 NC_009616.1 252658 252987 R PFAM: protein of unknown function DUF322; hypothetical protein complement(252658..252987) Thermosipho melanesiensis BI429 5297505 YP_001305511.1 CDS Tmel_0252 NC_009616.1 252962 254803 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(252962..254803) Thermosipho melanesiensis BI429 5297506 YP_001305512.1 CDS Tmel_0253 NC_009616.1 254814 256091 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(254814..256091) Thermosipho melanesiensis BI429 5297190 YP_001305513.1 CDS Tmel_0254 NC_009616.1 256097 257137 R TIGRFAM: putative translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; aIF-2BI family translation initiation factor complement(256097..257137) Thermosipho melanesiensis BI429 5296904 YP_001305514.1 CDS Tmel_0255 NC_009616.1 257214 258200 R hypothetical protein complement(257214..258200) Thermosipho melanesiensis BI429 5296905 YP_001305515.1 CDS leuS NC_009616.1 258214 260685 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(258214..260685) Thermosipho melanesiensis BI429 5297116 YP_001305516.1 CDS Tmel_0257 NC_009616.1 260764 261444 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 260764..261444 Thermosipho melanesiensis BI429 5297117 YP_001305517.1 CDS Tmel_0258 NC_009616.1 261459 261818 D hypothetical protein 261459..261818 Thermosipho melanesiensis BI429 5297225 YP_001305518.1 CDS Tmel_0259 NC_009616.1 261823 262254 R PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase complement(261823..262254) Thermosipho melanesiensis BI429 5296505 YP_001305519.1 CDS Tmel_0260 NC_009616.1 262265 263755 R PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; peptidase M50 complement(262265..263755) Thermosipho melanesiensis BI429 5296506 YP_001305520.1 CDS Tmel_0261 NC_009616.1 263742 265133 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; response regulator receiver modulated diguanylate cyclase complement(263742..265133) Thermosipho melanesiensis BI429 5297228 YP_001305521.1 CDS Tmel_0262 NC_009616.1 265126 266697 R TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(265126..266697) Thermosipho melanesiensis BI429 5297229 YP_001305522.1 CDS ispG NC_009616.1 266808 267839 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 266808..267839 Thermosipho melanesiensis BI429 5296826 YP_001305523.1 CDS Tmel_0264 NC_009616.1 267820 268851 R hypothetical protein complement(267820..268851) Thermosipho melanesiensis BI429 5297281 YP_001305524.1 CDS pyrC NC_009616.1 269251 270180 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 269251..270180 Thermosipho melanesiensis BI429 5297282 YP_001305525.1 CDS Tmel_0266 NC_009616.1 270158 270802 D 2-polyprenylphenol hydroxylase-like protein 270158..270802 Thermosipho melanesiensis BI429 5297469 YP_001305526.1 CDS Tmel_0267 NC_009616.1 270799 271614 D TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; dihydroorotate dehydrogenase family protein 270799..271614 Thermosipho melanesiensis BI429 5297470 YP_001305527.1 CDS Tmel_0268 NC_009616.1 271611 272222 D TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 271611..272222 Thermosipho melanesiensis BI429 5297860 YP_001305528.1 CDS Tmel_0269 NC_009616.1 272213 272779 D TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; orotate phosphoribosyltransferase 272213..272779 Thermosipho melanesiensis BI429 5296555 YP_001305529.1 CDS Tmel_0270 NC_009616.1 277715 278974 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(277715..278974) Thermosipho melanesiensis BI429 5297990 YP_001305530.1 CDS Tmel_0271 NC_009616.1 279027 280148 R PFAM: FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(279027..280148) Thermosipho melanesiensis BI429 5297145 YP_001305531.1 CDS Tmel_0274 NC_009616.1 282388 284376 D PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; RNA-binding S1 domain-containing protein 282388..284376 Thermosipho melanesiensis BI429 5297350 YP_001305532.1 CDS Tmel_0275 NC_009616.1 284381 284833 D PFAM: CheW domain protein; putative CheW protein 284381..284833 Thermosipho melanesiensis BI429 5297036 YP_001305533.1 CDS Tmel_0276 NC_009616.1 284826 287054 R TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; primosomal protein N' complement(284826..287054) Thermosipho melanesiensis BI429 5297037 YP_001305534.1 CDS Tmel_0277 NC_009616.1 287157 287366 D TIGRFAM: putative regulatory protein, FmdB family; FmdB family regulatory protein 287157..287366 Thermosipho melanesiensis BI429 5297006 YP_001305535.1 CDS Tmel_0278 NC_009616.1 287418 287615 R PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; cold-shock DNA-binding domain-containing protein complement(287418..287615) Thermosipho melanesiensis BI429 5297007 YP_001305536.1 CDS Tmel_0279 NC_009616.1 288273 288932 R PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase complement(288273..288932) Thermosipho melanesiensis BI429 5296677 YP_001305537.1 CDS Tmel_0280 NC_009616.1 288920 289633 R PFAM: biotin/lipoate A/B protein ligase; biotin/lipoate A/B protein ligase complement(288920..289633) Thermosipho melanesiensis BI429 5297670 YP_001305538.1 CDS Tmel_0281 NC_009616.1 289634 290233 R hypothetical protein complement(289634..290233) Thermosipho melanesiensis BI429 5297671 YP_001305539.1 CDS Tmel_0282 NC_009616.1 290235 291020 R hypothetical protein complement(290235..291020) Thermosipho melanesiensis BI429 5297155 YP_001305540.1 CDS Tmel_0283 NC_009616.1 291021 291215 R hypothetical protein complement(291021..291215) Thermosipho melanesiensis BI429 5297156 YP_001305541.1 CDS Tmel_0284 NC_009616.1 291215 291574 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(291215..291574) Thermosipho melanesiensis BI429 5297556 YP_001305542.1 CDS Tmel_0285 NC_009616.1 291576 294179 R TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; GAF domain protein; multi-sensor signal transduction histidine kinase complement(291576..294179) Thermosipho melanesiensis BI429 5296526 YP_001305543.1 CDS Tmel_0286 NC_009616.1 294257 294787 R TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; sigma 54 modulation protein/ribosomal protein S30EA complement(294257..294787) Thermosipho melanesiensis BI429 5296527 YP_001305544.1 CDS Tmel_0287 NC_009616.1 294799 295269 R hypothetical protein complement(294799..295269) Thermosipho melanesiensis BI429 5296977 YP_001305545.1 CDS Tmel_0288 NC_009616.1 295306 296127 R PFAM: DegV family protein; DegV family protein complement(295306..296127) Thermosipho melanesiensis BI429 5296978 YP_001305546.1 CDS atpC NC_009616.1 296132 296446 R produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon complement(296132..296446) Thermosipho melanesiensis BI429 5297481 YP_001305547.1 CDS Tmel_0290 NC_009616.1 296443 297852 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(296443..297852) Thermosipho melanesiensis BI429 5296886 YP_001305548.1 CDS Tmel_0291 NC_009616.1 297873 298694 R TIGRFAM: ATP synthase F1, gamma subunit; PFAM: H+-transporting two-sector ATPase, gamma subunit; ATP synthase F1 subunit gamma complement(297873..298694) Thermosipho melanesiensis BI429 5296887 YP_001305549.1 CDS Tmel_0292 NC_009616.1 298700 300223 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(298700..300223) Thermosipho melanesiensis BI429 5296928 YP_001305550.1 CDS Tmel_0293 NC_009616.1 300228 300767 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(300228..300767) Thermosipho melanesiensis BI429 5296929 YP_001305551.1 CDS Tmel_0294 NC_009616.1 300764 301249 R TIGRFAM: ATP synthase F0, B subunit; PFAM: H+-transporting two-sector ATPase, B/B' subunit; ATP synthase F0 subunit B complement(300764..301249) Thermosipho melanesiensis BI429 5297662 YP_001305552.1 CDS Tmel_0295 NC_009616.1 301264 301515 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(301264..301515) Thermosipho melanesiensis BI429 5296766 YP_001305553.1 CDS Tmel_0296 NC_009616.1 301530 302372 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(301530..302372) Thermosipho melanesiensis BI429 5296767 YP_001305554.1 CDS Tmel_0297 NC_009616.1 302356 302730 R hypothetical protein complement(302356..302730) Thermosipho melanesiensis BI429 5296947 YP_001305555.1 CDS Tmel_0298 NC_009616.1 302714 302962 R hypothetical protein complement(302714..302962) Thermosipho melanesiensis BI429 5296948 YP_001305556.1 CDS Tmel_0299 NC_009616.1 302959 304026 R PFAM: creatinase; peptidase M24; peptidase M24 complement(302959..304026) Thermosipho melanesiensis BI429 5297418 YP_001305557.1 CDS Tmel_0300 NC_009616.1 304125 304733 R PFAM: Holliday junction resolvase YqgF; SMART: Resolvase, RNase H domain protein fold; Holliday junction resolvase YqgF complement(304125..304733) Thermosipho melanesiensis BI429 5298017 YP_001305558.1 CDS Tmel_0301 NC_009616.1 304742 307675 R TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; single-stranded-DNA-specific exonuclease RecJ complement(304742..307675) Thermosipho melanesiensis BI429 5296891 YP_001305559.1 CDS Tmel_0302 NC_009616.1 308062 308925 D PFAM: Hsp33 protein; Hsp33 protein 308062..308925 Thermosipho melanesiensis BI429 5297763 YP_001305560.1 CDS Tmel_0303 NC_009616.1 308922 310091 D PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; integral membrane sensor signal transduction histidine kinase 308922..310091 Thermosipho melanesiensis BI429 5297764 YP_001305561.1 CDS Tmel_0304 NC_009616.1 310081 311736 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 310081..311736 Thermosipho melanesiensis BI429 5296808 YP_001305562.1 CDS Tmel_0305 NC_009616.1 311910 313193 D PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Glu/Leu/Phe/Val dehydrogenase, C terminal 311910..313193 Thermosipho melanesiensis BI429 5297223 YP_001305563.1 CDS Tmel_0306 NC_009616.1 313375 314154 R PFAM: putative RNA methylase; putative RNA methylase complement(313375..314154) Thermosipho melanesiensis BI429 5297224 YP_001305564.1 CDS Tmel_0307 NC_009616.1 314157 314975 R PFAM: DpmII restriction endonuclease; Type II site-specific deoxyribonuclease complement(314157..314975) Thermosipho melanesiensis BI429 5297178 YP_001305565.1 CDS Tmel_0308 NC_009616.1 314995 315927 R TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase complement(314995..315927) Thermosipho melanesiensis BI429 5297179 YP_001305566.1 CDS Tmel_0309 NC_009616.1 316122 316241 R hypothetical protein complement(316122..316241) Thermosipho melanesiensis BI429 5297576 YP_001305567.1 CDS acpP NC_009616.1 316429 316659 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(316429..316659) Thermosipho melanesiensis BI429 5297457 YP_001305568.1 CDS Tmel_0311 NC_009616.1 316780 318321 R PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein complement(316780..318321) Thermosipho melanesiensis BI429 5297458 YP_001305569.1 CDS Tmel_0312 NC_009616.1 318352 318684 R PFAM: histidine triad (HIT) protein; histidine triad (HIT) protein complement(318352..318684) Thermosipho melanesiensis BI429 5296609 YP_001305570.1 CDS Tmel_0313 NC_009616.1 318698 319897 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(318698..319897) Thermosipho melanesiensis BI429 5296610 YP_001305571.1 CDS Tmel_0314 NC_009616.1 319913 321172 R hypothetical protein complement(319913..321172) Thermosipho melanesiensis BI429 5297872 YP_001305572.1 CDS Tmel_0315 NC_009616.1 321174 321845 R catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase complement(321174..321845) Thermosipho melanesiensis BI429 5296814 YP_001305573.1 CDS Tmel_0316 NC_009616.1 321960 323327 D hypothetical protein 321960..323327 Thermosipho melanesiensis BI429 5296815 YP_001305574.1 CDS Tmel_0317 NC_009616.1 323331 323918 D MutT family phosphoesterase 323331..323918 Thermosipho melanesiensis BI429 5297040 YP_001305575.1 CDS Tmel_0318 NC_009616.1 323873 324697 D TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 323873..324697 Thermosipho melanesiensis BI429 5297041 YP_001305576.1 CDS Tmel_0319 NC_009616.1 324678 327029 D PFAM: peptidase S16, lon domain protein; peptidase S16, lon domain-containing protein 324678..327029 Thermosipho melanesiensis BI429 5296536 YP_001305577.1 CDS Tmel_0320 NC_009616.1 327034 328029 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 327034..328029 Thermosipho melanesiensis BI429 5296968 YP_001305578.1 CDS Tmel_0321 NC_009616.1 328035 328820 D PFAM: MscS Mechanosensitive ion channel; mechanosensitive ion channel MscS 328035..328820 Thermosipho melanesiensis BI429 5296969 YP_001305579.1 CDS Tmel_0322 NC_009616.1 328909 330897 D PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 328909..330897 Thermosipho melanesiensis BI429 5297579 YP_001305580.1 CDS Tmel_0324 NC_009616.1 331607 331774 R hypothetical protein complement(331607..331774) Thermosipho melanesiensis BI429 5298012 YP_001305581.1 CDS Tmel_0326 NC_009616.1 332217 332468 D putative anti-sigma-28 factor FlgM 332217..332468 Thermosipho melanesiensis BI429 5298013 YP_001305582.1 CDS Tmel_0327 NC_009616.1 332472 332903 D hypothetical protein 332472..332903 Thermosipho melanesiensis BI429 5297811 YP_001305583.1 CDS Tmel_0328 NC_009616.1 332915 335455 D TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar hook-associated protein FlgK 332915..335455 Thermosipho melanesiensis BI429 5297812 YP_001305584.1 CDS Tmel_0329 NC_009616.1 335467 336354 D TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; flagellar hook-associated protein 3 335467..336354 Thermosipho melanesiensis BI429 5297114 YP_001305585.1 CDS Tmel_0330 NC_009616.1 336351 337004 D O-methyltransferase-like protein 336351..337004 Thermosipho melanesiensis BI429 5297115 YP_001305586.1 CDS Tmel_0331 NC_009616.1 337037 338962 D PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; putative adenylate/guanylate cyclase 337037..338962 Thermosipho melanesiensis BI429 5297904 YP_001305587.1 CDS Tmel_0332 NC_009616.1 338955 339848 D putative metal dependent phosphohydrolase 338955..339848 Thermosipho melanesiensis BI429 5297739 YP_001305588.1 CDS Tmel_0333 NC_009616.1 339841 340470 D hypothetical protein 339841..340470 Thermosipho melanesiensis BI429 5297740 YP_001305589.1 CDS Tmel_0334 NC_009616.1 340467 342461 D hypothetical protein 340467..342461 Thermosipho melanesiensis BI429 5297741 YP_001305590.1 CDS Tmel_0335 NC_009616.1 342466 343677 D PFAM: GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 342466..343677 Thermosipho melanesiensis BI429 5297742 YP_001305591.1 CDS Tmel_0336 NC_009616.1 343823 344473 D TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; L-serine dehydratase, iron-sulfur-dependent subunit beta 343823..344473 Thermosipho melanesiensis BI429 5298222 YP_001305592.1 CDS Tmel_0337 NC_009616.1 344470 345330 D TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; L-serine dehydratase, iron-sulfur-dependent subunit alpha 344470..345330 Thermosipho melanesiensis BI429 5297828 YP_001305593.1 CDS Tmel_0338 NC_009616.1 345452 346237 D hypothetical protein 345452..346237 Thermosipho melanesiensis BI429 5297829 YP_001305594.1 CDS Tmel_0339 NC_009616.1 346240 347844 D PFAM: glycoside hydrolase, family 57; Domain of unknown function DUF1957; hypothetical protein 346240..347844 Thermosipho melanesiensis BI429 5297981 YP_001305595.1 CDS Tmel_0340 NC_009616.1 347870 348445 D TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase subunit gamma 347870..348445 Thermosipho melanesiensis BI429 5297982 YP_001305596.1 CDS Tmel_0341 NC_009616.1 348438 348770 D TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase subunit delta 348438..348770 Thermosipho melanesiensis BI429 5296953 YP_001305597.1 CDS Tmel_0342 NC_009616.1 348784 349962 D PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 348784..349962 Thermosipho melanesiensis BI429 5296619 YP_001305598.1 CDS Tmel_0343 NC_009616.1 349976 350953 D PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein 349976..350953 Thermosipho melanesiensis BI429 5296620 YP_001305599.1 CDS Tmel_0344 NC_009616.1 351060 351977 D PFAM: glycosyl transferase, family 4; glycosyl transferase family protein 351060..351977 Thermosipho melanesiensis BI429 5296599 YP_001305600.1 CDS Tmel_0345 NC_009616.1 351967 352476 D hypothetical protein 351967..352476 Thermosipho melanesiensis BI429 5296600 YP_001305601.1 CDS Tmel_0346 NC_009616.1 357995 359677 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(357995..359677) Thermosipho melanesiensis BI429 5298207 YP_001305602.1 CDS Tmel_0347 NC_009616.1 360707 360967 R TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein complement(360707..360967) Thermosipho melanesiensis BI429 5296863 YP_001305603.1 CDS Tmel_0348 NC_009616.1 360970 361965 R TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; CRISPR-associated Cas1 family protein complement(360970..361965) Thermosipho melanesiensis BI429 5296864 YP_001305604.1 CDS Tmel_0349 NC_009616.1 361971 362447 R TIGRFAM: CRISPR-associated protein Cas4; PFAM: protein of unknown function DUF83; CRISPR-associated Cas4 family protein complement(361971..362447) Thermosipho melanesiensis BI429 5296642 YP_001305605.1 CDS Tmel_0350 NC_009616.1 362444 362836 R hypothetical protein complement(362444..362836) Thermosipho melanesiensis BI429 5296643 YP_001305606.1 CDS Tmel_0351 NC_009616.1 362898 364853 R TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; CRISPR-associated helicase Cas3 complement(362898..364853) Thermosipho melanesiensis BI429 5297272 YP_001305607.1 CDS Tmel_0352 NC_009616.1 364831 365592 R TIGRFAM: CRISPR-associated protein Cas5; CRISPR-associated Cas5 family protein complement(364831..365592) Thermosipho melanesiensis BI429 5297277 YP_001305608.1 CDS Tmel_0353 NC_009616.1 365604 366527 R hypothetical protein complement(365604..366527) Thermosipho melanesiensis BI429 5297278 YP_001305609.1 CDS Tmel_0354 NC_009616.1 366542 368242 R hypothetical protein complement(366542..368242) Thermosipho melanesiensis BI429 5297348 YP_001305610.1 CDS Tmel_0355 NC_009616.1 368254 368982 R TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated Cas family protein complement(368254..368982) Thermosipho melanesiensis BI429 5297349 YP_001305611.1 CDS Tmel_0356 NC_009616.1 369745 369930 R hypothetical protein complement(369745..369930) Thermosipho melanesiensis BI429 5297380 YP_001305612.1 CDS Tmel_0357 NC_009616.1 370396 370557 R hypothetical protein complement(370396..370557) Thermosipho melanesiensis BI429 5296658 YP_001305613.1 CDS Tmel_0358 NC_009616.1 371265 371684 R hypothetical protein complement(371265..371684) Thermosipho melanesiensis BI429 5298186 YP_001305614.1 CDS Tmel_0359 NC_009616.1 371773 372993 D PFAM: peptidase M48, Ste24p; Ste24 endopeptidase 371773..372993 Thermosipho melanesiensis BI429 5296821 YP_001305615.1 CDS Tmel_0361 NC_009616.1 373383 374831 D PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; polysaccharide biosynthesis protein 373383..374831 Thermosipho melanesiensis BI429 5298007 YP_001305616.1 CDS Tmel_0362 NC_009616.1 374837 375943 D hypothetical protein 374837..375943 Thermosipho melanesiensis BI429 5297575 YP_001305617.1 CDS Tmel_0363 NC_009616.1 375959 377110 D PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 375959..377110 Thermosipho melanesiensis BI429 5297720 YP_001305618.1 CDS Tmel_0364 NC_009616.1 377102 378277 R PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase complement(377102..378277) Thermosipho melanesiensis BI429 5297721 YP_001305619.1 CDS Tmel_0365 NC_009616.1 378279 379493 R PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase complement(378279..379493) Thermosipho melanesiensis BI429 5297691 YP_001305620.1 CDS Tmel_0366 NC_009616.1 379490 380551 R PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(379490..380551) Thermosipho melanesiensis BI429 5297692 YP_001305621.1 CDS Tmel_0367 NC_009616.1 380603 384073 R TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: phosphoribosyltransferase; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; ATP-dependent DNA helicase RecQ complement(380603..384073) Thermosipho melanesiensis BI429 5297234 YP_001305622.1 CDS Tmel_0368 NC_009616.1 384089 385060 D PFAM: SMF family protein; SMF family protein 384089..385060 Thermosipho melanesiensis BI429 5297955 YP_001305623.1 CDS Tmel_0369 NC_009616.1 385047 386303 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(385047..386303) Thermosipho melanesiensis BI429 5297956 YP_001305624.1 CDS Tmel_0370 NC_009616.1 386281 387309 R hypothetical protein complement(386281..387309) Thermosipho melanesiensis BI429 5296973 YP_001305625.1 CDS Tmel_0371 NC_009616.1 387302 387673 R hypothetical protein complement(387302..387673) Thermosipho melanesiensis BI429 5296974 YP_001305626.1 CDS obgE NC_009616.1 388000 389304 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 388000..389304 Thermosipho melanesiensis BI429 5298030 YP_001305627.1 CDS Tmel_0373 NC_009616.1 389288 389881 D TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; nicotinate (nicotinamide) nucleotide adenylyltransferase 389288..389881 Thermosipho melanesiensis BI429 5296831 YP_001305628.1 CDS Tmel_0374 NC_009616.1 389868 390755 D PFAM: dihydrouridine synthase, DuS; dihydrouridine synthase, DuS 389868..390755 Thermosipho melanesiensis BI429 5296832 YP_001305629.1 CDS Tmel_0375 NC_009616.1 390844 391815 D PFAM: polysaccharide deacetylase; polysaccharide deacetylase 390844..391815 Thermosipho melanesiensis BI429 5296675 YP_001305630.1 CDS Tmel_0376 NC_009616.1 391802 392923 D PFAM: aminotransferase, class I and II; Allinase-like; class I and II aminotransferase 391802..392923 Thermosipho melanesiensis BI429 5296676 YP_001305631.1 CDS Tmel_0377 NC_009616.1 392954 393613 D PFAM: 2-phosphosulfolactate phosphatase; 2-phosphosulfolactate phosphatase 392954..393613 Thermosipho melanesiensis BI429 5297641 YP_001305632.1 CDS Tmel_0378 NC_009616.1 393615 394493 D hypothetical protein 393615..394493 Thermosipho melanesiensis BI429 5296700 YP_001305633.1 CDS Tmel_0379 NC_009616.1 394490 396397 D PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; glycosyl transferase family protein 394490..396397 Thermosipho melanesiensis BI429 5296701 YP_001305634.1 CDS Tmel_0380 NC_009616.1 396397 396930 D hypothetical protein 396397..396930 Thermosipho melanesiensis BI429 5297129 YP_001305635.1 CDS Tmel_0381 NC_009616.1 396906 397349 D PFAM: nucleoside diphosphate kinase; nucleoside-diphosphate kinase 396906..397349 Thermosipho melanesiensis BI429 5297130 YP_001305636.1 CDS Tmel_0382 NC_009616.1 397350 398447 R PFAM: ABC-2 type transporter; ABC-2 type transporter complement(397350..398447) Thermosipho melanesiensis BI429 5296937 YP_001305637.1 CDS Tmel_0383 NC_009616.1 398452 399621 R hypothetical protein complement(398452..399621) Thermosipho melanesiensis BI429 5296623 YP_001305638.1 CDS Tmel_0384 NC_009616.1 399608 400243 R hypothetical protein complement(399608..400243) Thermosipho melanesiensis BI429 5296624 YP_001305639.1 CDS Tmel_0385 NC_009616.1 400309 401217 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(400309..401217) Thermosipho melanesiensis BI429 5296752 YP_001305640.1 CDS Tmel_0386 NC_009616.1 401214 402401 R TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; phosphoribosylamine--glycine ligase complement(401214..402401) Thermosipho melanesiensis BI429 5296753 YP_001305641.1 CDS Tmel_0387 NC_009616.1 402411 403304 R PFAM: AICARFT/IMPCHase bienzyme, formylation region; phosphoribosylaminoimidazolecarboxamide formyltransferase complement(402411..403304) Thermosipho melanesiensis BI429 5296682 YP_001305642.1 CDS Tmel_0388 NC_009616.1 403320 403877 R TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; phosphoribosylglycinamide formyltransferase complement(403320..403877) Thermosipho melanesiensis BI429 5296702 YP_001305643.1 CDS Tmel_0389 NC_009616.1 403841 405136 R TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; phosphoribosyltransferase; amidophosphoribosyltransferase complement(403841..405136) Thermosipho melanesiensis BI429 5296703 YP_001305644.1 CDS Tmel_0390 NC_009616.1 405601 406080 R hypothetical protein complement(405601..406080) Thermosipho melanesiensis BI429 5298050 YP_001305645.1 CDS Tmel_0391 NC_009616.1 406192 407652 R PFAM: Pyrrolo-quinoline quinone; Pyrrolo-quinoline quinone complement(406192..407652) Thermosipho melanesiensis BI429 5297623 YP_001305646.1 CDS Tmel_0392 NC_009616.1 407895 408104 R hypothetical protein complement(407895..408104) Thermosipho melanesiensis BI429 5296485 YP_001305647.1 CDS Tmel_0393 NC_009616.1 408914 411472 R hypothetical protein complement(408914..411472) Thermosipho melanesiensis BI429 5297861 YP_001305648.1 CDS Tmel_0394 NC_009616.1 411636 412364 D PFAM: Recombinase; recombinase 411636..412364 Thermosipho melanesiensis BI429 5297862 YP_001305649.1 CDS Tmel_0395 NC_009616.1 412755 412943 R hypothetical protein complement(412755..412943) Thermosipho melanesiensis BI429 5297385 YP_001305650.1 CDS Tmel_0396 NC_009616.1 413032 414216 R PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase complement(413032..414216) Thermosipho melanesiensis BI429 5297386 YP_001305651.1 CDS Tmel_0397 NC_009616.1 414879 416363 R PFAM: Resolvase, N-terminal domain; Recombinase; resolvase domain-containing protein complement(414879..416363) Thermosipho melanesiensis BI429 5297017 YP_001305652.1 CDS Tmel_0398 NC_009616.1 416711 417445 D PFAM: helix-turn-helix domain protein; XRE family transcriptional regulator 416711..417445 Thermosipho melanesiensis BI429 5296975 YP_001305653.1 CDS Tmel_0399 NC_009616.1 417898 418233 D hypothetical protein 417898..418233 Thermosipho melanesiensis BI429 5296976 YP_001305654.1 CDS Tmel_0400 NC_009616.1 418316 418513 D hypothetical protein 418316..418513 Thermosipho melanesiensis BI429 5297151 YP_001305655.1 CDS Tmel_0401 NC_009616.1 418794 419495 R PFAM: protein of unknown function DUF45; hypothetical protein complement(418794..419495) Thermosipho melanesiensis BI429 5297152 YP_001305656.1 CDS Tmel_0402 NC_009616.1 419495 422662 R TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like; HsdR family type I site-specific deoxyribonuclease complement(419495..422662) Thermosipho melanesiensis BI429 5297837 YP_001305657.1 CDS Tmel_0403 NC_009616.1 422659 423867 R PFAM: restriction modification system DNA specificity domain; restriction modification system DNA specificity subunit complement(422659..423867) Thermosipho melanesiensis BI429 5297660 YP_001305658.1 CDS Tmel_0404 NC_009616.1 423869 424324 R hypothetical protein complement(423869..424324) Thermosipho melanesiensis BI429 5297661 YP_001305659.1 CDS Tmel_0405 NC_009616.1 424321 426720 R TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; type I restriction-modification system, M subunit complement(424321..426720) Thermosipho melanesiensis BI429 5297522 YP_001305660.1 CDS Tmel_0406 NC_009616.1 427515 428210 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(427515..428210) Thermosipho melanesiensis BI429 5297523 YP_001305661.1 CDS Tmel_0407 NC_009616.1 428221 429147 R PFAM: ABC-2 type transporter; ABC-2 type transporter complement(428221..429147) Thermosipho melanesiensis BI429 5297440 YP_001305662.1 CDS Tmel_0408 NC_009616.1 429646 431130 R PFAM: peptidase S41; peptidase S41 complement(429646..431130) Thermosipho melanesiensis BI429 5297509 YP_001305663.1 CDS Tmel_0409 NC_009616.1 431261 432580 R PFAM: Radical SAM domain protein; radical SAM domain-containing protein complement(431261..432580) Thermosipho melanesiensis BI429 5297510 YP_001305664.1 CDS Tmel_0410 NC_009616.1 433152 433535 D PFAM: Transcriptional regulator IclR-like; transcriptional regulator IclR-like protein 433152..433535 Thermosipho melanesiensis BI429 5297732 YP_001305665.1 CDS Tmel_0412 NC_009616.1 434504 435082 R PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein complement(434504..435082) Thermosipho melanesiensis BI429 5298002 YP_001305666.1 CDS Tmel_0413 NC_009616.1 435264 437633 D PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase 435264..437633 Thermosipho melanesiensis BI429 5297926 YP_001305667.1 CDS Tmel_0414 NC_009616.1 437768 437926 D PFAM: Rubredoxin-type Fe(Cys)4 protein; rubredoxin-type Fe(Cys)4 protein 437768..437926 Thermosipho melanesiensis BI429 5297581 YP_001305668.1 CDS Tmel_0415 NC_009616.1 437938 438207 D hypothetical protein 437938..438207 Thermosipho melanesiensis BI429 5297582 YP_001305669.1 CDS Tmel_0416 NC_009616.1 438235 440028 R PFAM: chemotaxis sensory transducer; Heme NO binding domain protein; methyl-accepting chemotaxis sensory transducer complement(438235..440028) Thermosipho melanesiensis BI429 5297712 YP_001305670.1 CDS Tmel_0417 NC_009616.1 440076 440807 D PFAM: RNA-binding S4 domain protein; pseudouridine synthase; pseudouridine synthase 440076..440807 Thermosipho melanesiensis BI429 5297713 YP_001305671.1 CDS Tmel_0418 NC_009616.1 440804 441784 D TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; UDP-glucose 4-epimerase 440804..441784 Thermosipho melanesiensis BI429 5297061 YP_001305672.1 CDS Tmel_0419 NC_009616.1 441771 444782 D PFAM: UvrD/REP helicase; UvrD/REP helicase 441771..444782 Thermosipho melanesiensis BI429 5296811 YP_001305673.1 CDS Tmel_0420 NC_009616.1 444779 447679 D hypothetical protein 444779..447679 Thermosipho melanesiensis BI429 5296812 YP_001305674.1 CDS Tmel_0421 NC_009616.1 447821 448372 D hypothetical protein 447821..448372 Thermosipho melanesiensis BI429 5297855 YP_001305675.1 CDS Tmel_0422 NC_009616.1 448555 448800 R hypothetical protein complement(448555..448800) Thermosipho melanesiensis BI429 5297856 YP_001305676.1 CDS Tmel_0423 NC_009616.1 449046 450713 D Alpha-galactosidase-like protein 449046..450713 Thermosipho melanesiensis BI429 5297747 YP_001305677.1 CDS Tmel_0424 NC_009616.1 450706 451668 D TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; galactose-1-phosphate uridylyltransferase 450706..451668 Thermosipho melanesiensis BI429 5297304 YP_001305678.1 CDS Tmel_0425 NC_009616.1 451661 452716 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 451661..452716 Thermosipho melanesiensis BI429 5297305 YP_001305679.1 CDS Tmel_0427 NC_009616.1 454010 454378 D hypothetical protein 454010..454378 Thermosipho melanesiensis BI429 5298213 YP_001305680.1 CDS Tmel_0428 NC_009616.1 454616 454759 D hypothetical protein 454616..454759 Thermosipho melanesiensis BI429 5297431 YP_001305681.1 CDS Tmel_0429 NC_009616.1 454834 455112 R PFAM: histone family protein DNA-binding protein; histone family protein DNA-binding protein complement(454834..455112) Thermosipho melanesiensis BI429 5296484 YP_001305682.1 CDS Tmel_0430 NC_009616.1 455205 455678 R PFAM: shikimate kinase; shikimate kinase complement(455205..455678) Thermosipho melanesiensis BI429 5297076 YP_001305683.1 CDS Tmel_0431 NC_009616.1 455689 456087 R PFAM: protein of unknown function UPF0047; hypothetical protein complement(455689..456087) Thermosipho melanesiensis BI429 5297077 YP_001305684.1 CDS Tmel_0432 NC_009616.1 456218 456589 D PFAM: ferric-uptake regulator; ferric uptake regulator family protein 456218..456589 Thermosipho melanesiensis BI429 5297408 YP_001305685.1 CDS Tmel_0433 NC_009616.1 456586 457365 D PFAM: periplasmic solute binding protein; periplasmic solute binding protein 456586..457365 Thermosipho melanesiensis BI429 5297409 YP_001305686.1 CDS Tmel_0434 NC_009616.1 457358 458080 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 457358..458080 Thermosipho melanesiensis BI429 5297903 YP_001305687.1 CDS Tmel_0435 NC_009616.1 458067 458855 D PFAM: transport system permease protein; ABC-3 protein; ABC-3 protein 458067..458855 Thermosipho melanesiensis BI429 5297976 YP_001305688.1 CDS Tmel_0436 NC_009616.1 459010 459504 D hypothetical protein 459010..459504 Thermosipho melanesiensis BI429 5297977 YP_001305689.1 CDS Tmel_0437 NC_009616.1 459552 460430 D TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; riboflavin biosynthesis protein RibF 459552..460430 Thermosipho melanesiensis BI429 5297484 YP_001305690.1 CDS Tmel_0438 NC_009616.1 460420 461031 D TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; endonuclease III 460420..461031 Thermosipho melanesiensis BI429 5297485 YP_001305691.1 CDS Tmel_0439 NC_009616.1 461028 462155 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; DegT/DnrJ/EryC1/StrS aminotransferase 461028..462155 Thermosipho melanesiensis BI429 5297749 YP_001305692.1 CDS Tmel_0440 NC_009616.1 462159 462353 D hypothetical protein 462159..462353 Thermosipho melanesiensis BI429 5296924 YP_001305693.1 CDS Tmel_0441 NC_009616.1 462385 463725 D PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; xanthine/uracil/vitamin C permease 462385..463725 Thermosipho melanesiensis BI429 5296925 YP_001305694.1 CDS Tmel_0442 NC_009616.1 463947 465629 D hypothetical protein 463947..465629 Thermosipho melanesiensis BI429 5297520 YP_001305695.1 CDS Tmel_0443 NC_009616.1 465641 466027 D hypothetical protein 465641..466027 Thermosipho melanesiensis BI429 5297521 YP_001305696.1 CDS Tmel_0444 NC_009616.1 466029 466481 D hypothetical protein 466029..466481 Thermosipho melanesiensis BI429 5297705 YP_001305697.1 CDS Tmel_0445 NC_009616.1 466515 467303 R hypothetical protein complement(466515..467303) Thermosipho melanesiensis BI429 5297938 YP_001305698.1 CDS Tmel_0446 NC_009616.1 467309 470521 R PFAM: O-antigen polymerase; O-antigen polymerase complement(467309..470521) Thermosipho melanesiensis BI429 5297939 YP_001305699.1 CDS Tmel_0447 NC_009616.1 470602 471798 D hypothetical protein 470602..471798 Thermosipho melanesiensis BI429 5297500 YP_001305700.1 CDS Tmel_0448 NC_009616.1 471792 473558 D hypothetical protein 471792..473558 Thermosipho melanesiensis BI429 5297501 YP_001305701.1 CDS Tmel_0449 NC_009616.1 473594 474778 D hypothetical protein 473594..474778 Thermosipho melanesiensis BI429 5297669 YP_001305702.1 CDS Tmel_0450 NC_009616.1 474790 476820 D hypothetical protein 474790..476820 Thermosipho melanesiensis BI429 5296532 YP_001305703.1 CDS Tmel_0451 NC_009616.1 476842 477540 R PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(476842..477540) Thermosipho melanesiensis BI429 5296533 YP_001305704.1 CDS Tmel_0452 NC_009616.1 477733 478230 R hypothetical protein complement(477733..478230) Thermosipho melanesiensis BI429 5297315 YP_001305705.1 CDS Tmel_0453 NC_009616.1 478227 478649 R hypothetical protein complement(478227..478649) Thermosipho melanesiensis BI429 5297316 YP_001305706.1 CDS Tmel_0454 NC_009616.1 478747 479607 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 478747..479607 Thermosipho melanesiensis BI429 5298239 YP_001305707.1 CDS Tmel_0455 NC_009616.1 479613 480410 D hypothetical protein 479613..480410 Thermosipho melanesiensis BI429 5297745 YP_001305708.1 CDS Tmel_0456 NC_009616.1 480425 481219 D hypothetical protein 480425..481219 Thermosipho melanesiensis BI429 5297746 YP_001305709.1 CDS Tmel_0457 NC_009616.1 481231 481800 D PFAM: regulatory protein, TetR; TetR family transcriptional regulator 481231..481800 Thermosipho melanesiensis BI429 5297498 YP_001305710.1 CDS Tmel_0458 NC_009616.1 481856 483847 D PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 481856..483847 Thermosipho melanesiensis BI429 5297499 YP_001305711.1 CDS Tmel_0459 NC_009616.1 483861 486389 D TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase, family 13 domain protein; pullanase-associated protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; pullulanase, type I 483861..486389 Thermosipho melanesiensis BI429 5297863 YP_001305712.1 CDS Tmel_0460 NC_009616.1 486433 486792 D PFAM: response regulator receiver; response regulator receiver protein 486433..486792 Thermosipho melanesiensis BI429 5297672 YP_001305713.1 CDS ileS NC_009616.1 486876 489602 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 486876..489602 Thermosipho melanesiensis BI429 5297673 YP_001305714.1 CDS Tmel_0462 NC_009616.1 489640 490140 D PFAM: conserved hypothetical protein 730; hypothetical protein 489640..490140 Thermosipho melanesiensis BI429 5297610 YP_001305715.1 CDS Tmel_0463 NC_009616.1 490137 491006 D PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 490137..491006 Thermosipho melanesiensis BI429 5297611 YP_001305716.1 CDS Tmel_0464 NC_009616.1 490993 492000 D TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; rod shape-determining protein MreB 490993..492000 Thermosipho melanesiensis BI429 5297927 YP_001305717.1 CDS Tmel_0465 NC_009616.1 492010 492711 D PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; hypothetical protein 492010..492711 Thermosipho melanesiensis BI429 5298462 YP_001305718.1 CDS Tmel_0466 NC_009616.1 492725 493510 D TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal-body rod protein FlgG 492725..493510 Thermosipho melanesiensis BI429 5298463 YP_001305719.1 CDS Tmel_0467 NC_009616.1 493600 495144 D PFAM: protein of unknown function DUF1703; hypothetical protein 493600..495144 Thermosipho melanesiensis BI429 5297907 YP_001305720.1 CDS Tmel_0468 NC_009616.1 495175 495897 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(495175..495897) Thermosipho melanesiensis BI429 5297908 YP_001305721.1 CDS Tmel_0469 NC_009616.1 495894 496544 R TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; Ectoine/hydroxyectoine ABC transporter, permease protein EhuC; PFAM: binding-protein-dependent transport systems inner membrane component; ectoine/hydroxyectoine ABC transporter permease EhuC complement(495894..496544) Thermosipho melanesiensis BI429 5297439 YP_001305722.1 CDS Tmel_0470 NC_009616.1 496557 497300 R PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; extracellular solute-binding protein complement(496557..497300) Thermosipho melanesiensis BI429 5297034 YP_001305723.1 CDS Tmel_0471 NC_009616.1 497397 499202 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(497397..499202) Thermosipho melanesiensis BI429 5297035 YP_001305724.1 CDS Tmel_0472 NC_009616.1 499171 500172 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(499171..500172) Thermosipho melanesiensis BI429 5297667 YP_001305725.1 CDS rpmF NC_009616.1 500175 500357 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(500175..500357) Thermosipho melanesiensis BI429 5297668 YP_001305726.1 CDS Tmel_0474 NC_009616.1 500376 500924 R PFAM: protein of unknown function DUF177; hypothetical protein complement(500376..500924) Thermosipho melanesiensis BI429 5297128 YP_001305727.1 CDS Tmel_0475 NC_009616.1 500973 501926 D PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase 500973..501926 Thermosipho melanesiensis BI429 5298211 YP_001305728.1 CDS Tmel_0476 NC_009616.1 502073 503542 D TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring C-terminal domain protein; flagellar M-ring protein FliF 502073..503542 Thermosipho melanesiensis BI429 5298212 YP_001305729.1 CDS fliG NC_009616.1 503549 504559 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 503549..504559 Thermosipho melanesiensis BI429 5297789 YP_001305730.1 CDS Tmel_0478 NC_009616.1 504570 505124 D TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; DNA polymerase III subunit epsilon 504570..505124 Thermosipho melanesiensis BI429 5297790 YP_001305731.1 CDS Tmel_0479 NC_009616.1 505124 506356 D PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; PhoH family protein 505124..506356 Thermosipho melanesiensis BI429 5297871 YP_001305732.1 CDS Tmel_0480 NC_009616.1 506372 506923 D hypothetical protein 506372..506923 Thermosipho melanesiensis BI429 5298277 YP_001305733.1 CDS Tmel_0481 NC_009616.1 506917 509373 D hypothetical protein 506917..509373 Thermosipho melanesiensis BI429 5298278 YP_001305734.1 CDS pyrH NC_009616.1 509375 510076 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 509375..510076 Thermosipho melanesiensis BI429 5298299 YP_001305735.1 CDS Tmel_0483 NC_009616.1 510077 510853 D PFAM: GTP-binding protein, HSR1-related; HSR1-like GTP-binding protein 510077..510853 Thermosipho melanesiensis BI429 5298300 YP_001305736.1 CDS Tmel_0484 NC_009616.1 510838 511305 D PFAM: CheC domain protein; CheC domain-containing protein 510838..511305 Thermosipho melanesiensis BI429 5298014 YP_001305737.1 CDS Tmel_0485 NC_009616.1 511306 511959 D PFAM: purine or other phosphorylase, family 1; adenosylhomocysteine nucleosidase 511306..511959 Thermosipho melanesiensis BI429 5298235 YP_001305738.1 CDS Tmel_0486 NC_009616.1 511969 513054 D TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; D-alanine--D-alanine ligase 511969..513054 Thermosipho melanesiensis BI429 5298236 YP_001305739.1 CDS Tmel_0487 NC_009616.1 513051 513773 D PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 513051..513773 Thermosipho melanesiensis BI429 5298165 YP_001305740.1 CDS Tmel_0488 NC_009616.1 513775 515310 D PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; Mur ligase middle domain-containing protein 513775..515310 Thermosipho melanesiensis BI429 5298166 YP_001305741.1 CDS Tmel_0489 NC_009616.1 515360 515989 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(515360..515989) Thermosipho melanesiensis BI429 5298108 YP_001305742.1 CDS Tmel_0490 NC_009616.1 515973 517934 R PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; hydrogenase large subunit complement(515973..517934) Thermosipho melanesiensis BI429 5298061 YP_001305743.1 CDS Tmel_0491 NC_009616.1 517947 519818 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) complement(517947..519818) Thermosipho melanesiensis BI429 5298062 YP_001305744.1 CDS Tmel_0492 NC_009616.1 519820 520293 R PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit complement(519820..520293) Thermosipho melanesiensis BI429 5298385 YP_001305745.1 CDS Tmel_0493 NC_009616.1 520306 521445 R PFAM: Stage II sporulation E family protein; stage II sporulation E family protein complement(520306..521445) Thermosipho melanesiensis BI429 5298386 YP_001305746.1 CDS Tmel_0494 NC_009616.1 521447 523006 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(521447..523006) Thermosipho melanesiensis BI429 5298308 YP_001305747.1 CDS Tmel_0495 NC_009616.1 523012 523236 R NADH:ubiquinone oxidoreductase 24 kD subunit-like protein complement(523012..523236) Thermosipho melanesiensis BI429 5298294 YP_001305748.1 CDS Tmel_0496 NC_009616.1 523356 523622 D hypothetical protein 523356..523622 Thermosipho melanesiensis BI429 5298295 YP_001305749.1 CDS Tmel_0497 NC_009616.1 523833 525131 R PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; response regulator receiver modulated metal dependent phosphohydrolase complement(523833..525131) Thermosipho melanesiensis BI429 5298242 YP_001305750.1 CDS Tmel_0498 NC_009616.1 525124 526323 R PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; integral membrane sensor signal transduction histidine kinase complement(525124..526323) Thermosipho melanesiensis BI429 5298243 YP_001305751.1 CDS Tmel_0499 NC_009616.1 526316 527689 R SMART: extracellular solute-binding protein, family 3; extracellular solute-binding protein complement(526316..527689) Thermosipho melanesiensis BI429 5298353 YP_001305752.1 CDS Tmel_0500 NC_009616.1 527778 528917 R PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase complement(527778..528917) Thermosipho melanesiensis BI429 5298197 YP_001305753.1 CDS Tmel_0501 NC_009616.1 528996 533945 R TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 4; SMART: RNA polymerase I subunit A domain protein; DNA-directed RNA polymerase subunit beta' complement(528996..533945) Thermosipho melanesiensis BI429 5298198 YP_001305754.1 CDS rpoB NC_009616.1 533965 537483 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(533965..537483) Thermosipho melanesiensis BI429 5298409 YP_001305755.1 CDS rplL NC_009616.1 537619 538008 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(537619..538008) Thermosipho melanesiensis BI429 5298410 YP_001305756.1 CDS Tmel_0504 NC_009616.1 538026 538568 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(538026..538568) Thermosipho melanesiensis BI429 5298358 YP_001305757.1 CDS Tmel_0505 NC_009616.1 539155 539784 D PFAM: WbqC-like protein family; WbqC-like family protein 539155..539784 Thermosipho melanesiensis BI429 5298380 YP_001305758.1 CDS Tmel_0506 NC_009616.1 539813 540772 D PFAM: Radical SAM domain protein; radical SAM domain-containing protein 539813..540772 Thermosipho melanesiensis BI429 5298381 YP_001305759.1 CDS Tmel_0507 NC_009616.1 540769 541767 D PFAM: Radical SAM domain protein; radical SAM domain-containing protein 540769..541767 Thermosipho melanesiensis BI429 5298271 YP_001305760.1 CDS Tmel_0508 NC_009616.1 541769 543649 D TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; asparagine synthase 541769..543649 Thermosipho melanesiensis BI429 5298272 YP_001305761.1 CDS Tmel_0509 NC_009616.1 543662 544801 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 543662..544801 Thermosipho melanesiensis BI429 5298159 YP_001305762.1 CDS Tmel_0510 NC_009616.1 544805 545461 D PFAM: formyl transferase domain protein; formyl transferase domain-containing protein 544805..545461 Thermosipho melanesiensis BI429 5298305 YP_001305763.1 CDS Tmel_0511 NC_009616.1 545479 546351 D TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidylyltransferase 545479..546351 Thermosipho melanesiensis BI429 5298306 YP_001305764.1 CDS Tmel_0512 NC_009616.1 546365 547384 D TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; dTDP-glucose 4,6-dehydratase 546365..547384 Thermosipho melanesiensis BI429 5298015 YP_001305765.1 CDS Tmel_0513 NC_009616.1 547428 550202 D PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 547428..550202 Thermosipho melanesiensis BI429 5298016 YP_001305766.1 CDS Tmel_0514 NC_009616.1 550245 551405 R PFAM: flagellin domain protein; flagellin domain-containing protein complement(550245..551405) Thermosipho melanesiensis BI429 5298180 YP_001305767.1 CDS Tmel_0515 NC_009616.1 551484 554057 R PFAM: glycosyl transferase, family 2; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; glycosyl transferase family protein complement(551484..554057) Thermosipho melanesiensis BI429 5298395 YP_001305768.1 CDS coaD NC_009616.1 554062 554541 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(554062..554541) Thermosipho melanesiensis BI429 5298396 YP_001305769.1 CDS Tmel_0517 NC_009616.1 554545 555882 R TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase; replicative DNA helicase complement(554545..555882) Thermosipho melanesiensis BI429 5298257 YP_001305770.1 CDS Tmel_0518 NC_009616.1 556173 557345 R RecB family-like nuclease complement(556173..557345) Thermosipho melanesiensis BI429 5298258 YP_001305771.1 CDS Tmel_0519 NC_009616.1 557451 558995 D PFAM: protein of unknown function DUF1703; hypothetical protein 557451..558995 Thermosipho melanesiensis BI429 5298238 YP_001305772.1 CDS Tmel_0520 NC_009616.1 559013 560566 D PFAM: protein of unknown function DUF1703; hypothetical protein 559013..560566 Thermosipho melanesiensis BI429 5298400 YP_001305773.1 CDS Tmel_0521 NC_009616.1 560569 560940 D TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; putative endoribonuclease L-PSP 560569..560940 Thermosipho melanesiensis BI429 5298401 YP_001305774.1 CDS Tmel_0522 NC_009616.1 560943 561593 D PFAM: helix-hairpin-helix motif; HhH-GPD family protein; HhH-GPD family protein 560943..561593 Thermosipho melanesiensis BI429 5298424 YP_001305775.1 CDS Tmel_0523 NC_009616.1 561563 562813 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(561563..562813) Thermosipho melanesiensis BI429 5298425 YP_001305776.1 CDS Tmel_0524 NC_009616.1 562908 563288 D TIGRFAM: methylglyoxal synthase; PFAM: MGS domain protein; methylglyoxal synthase 562908..563288 Thermosipho melanesiensis BI429 5298204 YP_001305777.1 CDS Tmel_0525 NC_009616.1 563293 564090 D TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3; Cof-like hydrolase 563293..564090 Thermosipho melanesiensis BI429 5298111 YP_001305778.1 CDS Tmel_0526 NC_009616.1 564038 564745 D hypothetical protein 564038..564745 Thermosipho melanesiensis BI429 5298112 YP_001305779.1 CDS Tmel_0527 NC_009616.1 564764 566059 D TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; asparaginyl-tRNA synthetase 564764..566059 Thermosipho melanesiensis BI429 5298093 YP_001305780.1 CDS Tmel_0528 NC_009616.1 566130 567605 R PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase; carboxypeptidase Taq complement(566130..567605) Thermosipho melanesiensis BI429 5298094 YP_001305781.1 CDS Tmel_0529 NC_009616.1 567621 568454 R PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase complement(567621..568454) Thermosipho melanesiensis BI429 5298058 YP_001305782.1 CDS Tmel_0530 NC_009616.1 568435 568773 R PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; ribosomal protein L7Ae/L30e/S12e/Gadd45 complement(568435..568773) Thermosipho melanesiensis BI429 5298113 YP_001305783.1 CDS Tmel_0531 NC_009616.1 568776 569555 R PFAM: protein of unknown function DUF198; hypothetical protein complement(568776..569555) Thermosipho melanesiensis BI429 5298114 YP_001305784.1 CDS Tmel_0532 NC_009616.1 569558 569767 R hypothetical protein complement(569558..569767) Thermosipho melanesiensis BI429 5298117 YP_001305785.1 CDS Tmel_0533 NC_009616.1 569772 571043 R PFAM: glycosyl transferase, group 1; sucrose synthase complement(569772..571043) Thermosipho melanesiensis BI429 5298118 YP_001305786.1 CDS Tmel_0534 NC_009616.1 571024 571905 R PFAM: PfkB domain protein; ribokinase-like domain-containing protein complement(571024..571905) Thermosipho melanesiensis BI429 5298151 YP_001305787.1 CDS Tmel_0535 NC_009616.1 571980 573080 D TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; DNA polymerase III subunit beta 571980..573080 Thermosipho melanesiensis BI429 5297853 YP_001305788.1 CDS Tmel_0536 NC_009616.1 573094 573513 D hypothetical protein 573094..573513 Thermosipho melanesiensis BI429 5297854 YP_001305789.1 CDS Tmel_0537 NC_009616.1 573510 574280 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 573510..574280 Thermosipho melanesiensis BI429 5297784 YP_001305790.1 CDS Tmel_0538 NC_009616.1 574273 574674 D hypothetical protein 574273..574674 Thermosipho melanesiensis BI429 5297785 YP_001305791.1 CDS Tmel_0539 NC_009616.1 574699 575862 R PFAM: flagellin domain protein; flagellin domain-containing protein complement(574699..575862) Thermosipho melanesiensis BI429 5297314 YP_001305792.1 CDS Tmel_0540 NC_009616.1 575979 576959 D PFAM: Radical SAM domain protein; radical SAM domain-containing protein 575979..576959 Thermosipho melanesiensis BI429 5298038 YP_001305793.1 CDS Tmel_0541 NC_009616.1 576956 577987 D PFAM: ApbE family lipoprotein; ApbE family lipoprotein 576956..577987 Thermosipho melanesiensis BI429 5298039 YP_001305794.1 CDS Tmel_0542 NC_009616.1 578000 578335 D PFAM: conserved hypothetical protein 103; hypothetical protein 578000..578335 Thermosipho melanesiensis BI429 5296771 YP_001305795.1 CDS Tmel_0543 NC_009616.1 578344 579015 D PFAM: Rhomboid family protein; rhomboid family protein 578344..579015 Thermosipho melanesiensis BI429 5296772 YP_001305796.1 CDS Tmel_0544 NC_009616.1 579012 580052 D hypothetical protein 579012..580052 Thermosipho melanesiensis BI429 5297655 YP_001305797.1 CDS Tmel_0545 NC_009616.1 580070 580597 R hypothetical protein complement(580070..580597) Thermosipho melanesiensis BI429 5296559 YP_001305798.1 CDS Tmel_0546 NC_009616.1 580751 581998 D PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; ErfK/YbiS/YcfS/YnhG family protein 580751..581998 Thermosipho melanesiensis BI429 5296560 YP_001305799.1 CDS Tmel_0547 NC_009616.1 582000 582620 D PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; short-chain dehydrogenase/reductase SDR 582000..582620 Thermosipho melanesiensis BI429 5296726 YP_001305800.1 CDS Tmel_0548 NC_009616.1 582593 584782 R TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; glycogen debranching protein GlgX complement(582593..584782) Thermosipho melanesiensis BI429 5296727 YP_001305801.1 CDS Tmel_0549 NC_009616.1 584784 585227 R PFAM: OsmC family protein; OsmC family protein complement(584784..585227) Thermosipho melanesiensis BI429 5296586 YP_001305802.1 CDS Tmel_0550 NC_009616.1 585224 585862 R PFAM: cytochrome c biogenesis protein, transmembrane region; cytochrome c biogenesis protein, transmembrane region complement(585224..585862) Thermosipho melanesiensis BI429 5296584 YP_001305803.1 CDS Tmel_0551 NC_009616.1 585867 586538 R thioredoxin-like protein complement(585867..586538) Thermosipho melanesiensis BI429 5296585 YP_001305804.1 CDS Tmel_0552 NC_009616.1 586675 586917 R TIGRFAM: glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin; glutaredoxin 2; YruB family glutaredoxin-like protein complement(586675..586917) Thermosipho melanesiensis BI429 5296521 YP_001305805.1 CDS Tmel_0553 NC_009616.1 586930 587880 R TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; thioredoxin reductase complement(586930..587880) Thermosipho melanesiensis BI429 5296522 YP_001305806.1 CDS Tmel_0554 NC_009616.1 587892 588554 R TIGRFAM: glutaredoxin-like domain protein; glutaredoxin-like domain-containing protein complement(587892..588554) Thermosipho melanesiensis BI429 5297497 YP_001305807.1 CDS Tmel_0555 NC_009616.1 588883 589416 D PFAM: NUDIX hydrolase; NUDIX hydrolase 588883..589416 Thermosipho melanesiensis BI429 5298214 YP_001305808.1 CDS Tmel_0556 NC_009616.1 589418 590017 D hypothetical protein 589418..590017 Thermosipho melanesiensis BI429 5297496 YP_001305809.1 CDS Tmel_0557 NC_009616.1 590031 590441 D PFAM: flagellar protein FliS; flagellar protein FliS 590031..590441 Thermosipho melanesiensis BI429 5297416 YP_001305810.1 CDS Tmel_0558 NC_009616.1 590454 590654 D hypothetical protein 590454..590654 Thermosipho melanesiensis BI429 5297417 YP_001305811.1 CDS Tmel_0559 NC_009616.1 590678 591910 R PFAM: uncharacterised conserved protein UCP033563; hypothetical protein complement(590678..591910) Thermosipho melanesiensis BI429 5297629 YP_001305812.1 CDS Tmel_0560 NC_009616.1 592068 593072 R TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase complement(592068..593072) Thermosipho melanesiensis BI429 5296652 YP_001305813.1 CDS Tmel_0561 NC_009616.1 593053 594057 R TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase complement(593053..594057) Thermosipho melanesiensis BI429 5296653 YP_001305814.1 CDS Tmel_0562 NC_009616.1 594064 596586 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(594064..596586) Thermosipho melanesiensis BI429 5297770 YP_001305815.1 CDS Tmel_0563 NC_009616.1 596600 598033 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(596600..598033) Thermosipho melanesiensis BI429 5297771 YP_001305816.1 CDS Tmel_0564 NC_009616.1 598091 599914 R PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein complement(598091..599914) Thermosipho melanesiensis BI429 5296571 YP_001305817.1 CDS Tmel_0565 NC_009616.1 600064 600618 D TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; putative methyltransferase 600064..600618 Thermosipho melanesiensis BI429 5297273 YP_001305818.1 CDS Tmel_0566 NC_009616.1 600586 601356 R PFAM: binding-protein-dependent transport systems inner membrane component; ornithine carbamoyltransferase complement(600586..601356) Thermosipho melanesiensis BI429 5297274 YP_001305819.1 CDS Tmel_0567 NC_009616.1 601353 602162 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(601353..602162) Thermosipho melanesiensis BI429 5297300 YP_001305820.1 CDS Tmel_0568 NC_009616.1 602162 603253 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein complement(602162..603253) Thermosipho melanesiensis BI429 5297301 YP_001305821.1 CDS Tmel_0569 NC_009616.1 603265 604287 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(603265..604287) Thermosipho melanesiensis BI429 5297646 YP_001305822.1 CDS Tmel_0570 NC_009616.1 604361 605269 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(604361..605269) Thermosipho melanesiensis BI429 5296567 YP_001305823.1 CDS Tmel_0571 NC_009616.1 605272 605664 R PFAM: S-adenosylmethionine decarboxylase related; adenosylmethionine decarboxylase complement(605272..605664) Thermosipho melanesiensis BI429 5296568 YP_001305824.1 CDS Tmel_0572 NC_009616.1 605685 606221 R PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; cupin 2 domain-containing protein complement(605685..606221) Thermosipho melanesiensis BI429 5296908 YP_001305825.1 CDS Tmel_0573 NC_009616.1 606415 607839 D PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphomannomutase 606415..607839 Thermosipho melanesiensis BI429 5296909 YP_001305826.1 CDS Tmel_0574 NC_009616.1 607856 608638 R hypothetical protein complement(607856..608638) Thermosipho melanesiensis BI429 5296669 YP_001305827.1 CDS Tmel_0575 NC_009616.1 608656 609321 R PFAM: protein of unknown function DUF554; hypothetical protein complement(608656..609321) Thermosipho melanesiensis BI429 5296918 YP_001305828.1 CDS Tmel_0576 NC_009616.1 609337 610170 R PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein complement(609337..610170) Thermosipho melanesiensis BI429 5296919 YP_001305829.1 CDS Tmel_0577 NC_009616.1 610151 610567 R PFAM: protein of unknown function UPF0054; hypothetical protein complement(610151..610567) Thermosipho melanesiensis BI429 5297042 YP_001305830.1 CDS Tmel_0578 NC_009616.1 610551 611912 R TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(610551..611912) Thermosipho melanesiensis BI429 5297043 YP_001305831.1 CDS Tmel_0579 NC_009616.1 611899 612855 R PFAM: PhoH family protein; PhoH family protein complement(611899..612855) Thermosipho melanesiensis BI429 5296657 YP_001305832.1 CDS Tmel_0580 NC_009616.1 612865 613560 R SMART: Tetratricopeptide domain protein; tetratricopeptide domain-containing protein complement(612865..613560) Thermosipho melanesiensis BI429 5297453 YP_001305833.1 CDS Tmel_0581 NC_009616.1 613588 614466 R TIGRFAM: LAO/AO transport system ATPase; PFAM: cobalamin synthesis protein, P47K; ArgK protein; LAO/AO transport system ATPase complement(613588..614466) Thermosipho melanesiensis BI429 5297454 YP_001305834.1 CDS Tmel_0582 NC_009616.1 614463 614864 R PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein complement(614463..614864) Thermosipho melanesiensis BI429 5296557 YP_001305835.1 CDS Tmel_0583 NC_009616.1 614875 615270 R PFAM: biotin/lipoyl attachment domain-containing protein; biotin/lipoyl attachment domain-containing protein complement(614875..615270) Thermosipho melanesiensis BI429 5296558 YP_001305836.1 CDS Tmel_0584 NC_009616.1 615243 615554 R hypothetical protein complement(615243..615554) Thermosipho melanesiensis BI429 5296823 YP_001305837.1 CDS Tmel_0585 NC_009616.1 615565 617103 R PFAM: carboxyl transferase; carboxyl transferase complement(615565..617103) Thermosipho melanesiensis BI429 5297237 YP_001305838.1 CDS Tmel_0586 NC_009616.1 617118 617525 R PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase complement(617118..617525) Thermosipho melanesiensis BI429 5297238 YP_001305839.1 CDS Tmel_0587 NC_009616.1 617590 617907 R PFAM: cyclic nucleotide-binding; cyclic nucleotide-binding protein complement(617590..617907) Thermosipho melanesiensis BI429 5297195 YP_001305840.1 CDS Tmel_0588 NC_009616.1 617894 618613 R hypothetical protein complement(617894..618613) Thermosipho melanesiensis BI429 5297196 YP_001305841.1 CDS secA NC_009616.1 618619 621180 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(618619..621180) Thermosipho melanesiensis BI429 5296895 YP_001305842.1 CDS Tmel_0590 NC_009616.1 621196 622245 R PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase complement(621196..622245) Thermosipho melanesiensis BI429 5296965 YP_001305843.1 CDS Tmel_0591 NC_009616.1 622347 622820 D PFAM: Rubrerythrin; rubrerythrin 622347..622820 Thermosipho melanesiensis BI429 5296966 YP_001305844.1 CDS Tmel_0592 NC_009616.1 622817 623581 R hypothetical protein complement(622817..623581) Thermosipho melanesiensis BI429 5297445 YP_001305845.1 CDS Tmel_0593 NC_009616.1 623568 623954 R hypothetical protein complement(623568..623954) Thermosipho melanesiensis BI429 5297446 YP_001305846.1 CDS Tmel_0594 NC_009616.1 624015 626396 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(624015..626396) Thermosipho melanesiensis BI429 5297003 YP_001305847.1 CDS Tmel_0595 NC_009616.1 626396 628102 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(626396..628102) Thermosipho melanesiensis BI429 5296779 YP_001305848.1 CDS Tmel_0596 NC_009616.1 628161 629333 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(628161..629333) Thermosipho melanesiensis BI429 5296780 YP_001305849.1 CDS Tmel_0597 NC_009616.1 629425 631626 R PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; ATPase complement(629425..631626) Thermosipho melanesiensis BI429 5296938 YP_001305850.1 CDS Tmel_0598 NC_009616.1 631628 632719 R TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; Amidohydrolase 3; isoaspartyl dipeptidase complement(631628..632719) Thermosipho melanesiensis BI429 5296939 YP_001305851.1 CDS Tmel_0599 NC_009616.1 632924 633415 D PFAM: Abortive infection protein; abortive infection protein 632924..633415 Thermosipho melanesiensis BI429 5296481 YP_001305852.1 CDS Tmel_0600 NC_009616.1 633457 633813 D PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein 633457..633813 Thermosipho melanesiensis BI429 5297451 YP_001305853.1 CDS Tmel_0601 NC_009616.1 633834 634784 R PFAM: SufBD protein; SufBD protein complement(633834..634784) Thermosipho melanesiensis BI429 5297452 YP_001305854.1 CDS Tmel_0602 NC_009616.1 634774 635517 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(634774..635517) Thermosipho melanesiensis BI429 5297053 YP_001305855.1 CDS Tmel_0603 NC_009616.1 635648 636886 R PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Glu/Leu/Phe/Val dehydrogenase, C terminal complement(635648..636886) Thermosipho melanesiensis BI429 5297054 YP_001305856.1 CDS Tmel_0604 NC_009616.1 647362 649314 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 647362..649314 Thermosipho melanesiensis BI429 5298334 YP_001305857.1 CDS Tmel_0605 NC_009616.1 649325 649855 D hypothetical protein 649325..649855 Thermosipho melanesiensis BI429 5297258 YP_001305858.1 CDS Tmel_0606 NC_009616.1 649837 652338 D TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 649837..652338 Thermosipho melanesiensis BI429 5297259 YP_001305859.1 CDS Tmel_0610 NC_009616.1 653346 653819 D hypothetical protein 653346..653819 Thermosipho melanesiensis BI429 5298351 YP_001305860.1 CDS Tmel_0611 NC_009616.1 653854 654606 R hypothetical protein complement(653854..654606) Thermosipho melanesiensis BI429 5296907 YP_001305861.1 CDS Tmel_0612 NC_009616.1 655077 655607 R hypothetical protein complement(655077..655607) Thermosipho melanesiensis BI429 5298022 YP_001305862.1 CDS Tmel_0613 NC_009616.1 655592 655810 R hypothetical protein complement(655592..655810) Thermosipho melanesiensis BI429 5296720 YP_001305863.1 CDS Tmel_0614 NC_009616.1 655855 657438 R PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; OB-fold, tRNA/helicase-type nucleic acid binding protein complement(655855..657438) Thermosipho melanesiensis BI429 5296721 YP_001305864.1 CDS Tmel_0615 NC_009616.1 657498 657929 R hypothetical protein complement(657498..657929) Thermosipho melanesiensis BI429 5296708 YP_001305865.1 CDS Tmel_0616 NC_009616.1 658247 658807 R PFAM: glycerol-3-phosphate responsive antiterminator; glycerol-3-phosphate responsive antiterminator complement(658247..658807) Thermosipho melanesiensis BI429 5296709 YP_001305866.1 CDS Tmel_0617 NC_009616.1 658800 660269 R TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; glycerol kinase complement(658800..660269) Thermosipho melanesiensis BI429 5297791 YP_001305867.1 CDS Tmel_0618 NC_009616.1 660288 660650 R PFAM: protein of unknown function DUF1667; hypothetical protein complement(660288..660650) Thermosipho melanesiensis BI429 5296954 YP_001305868.1 CDS Tmel_0619 NC_009616.1 660643 661863 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(660643..661863) Thermosipho melanesiensis BI429 5296955 YP_001305869.1 CDS Tmel_0620 NC_009616.1 661860 663296 R PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; FAD dependent oxidoreductase complement(661860..663296) Thermosipho melanesiensis BI429 5296995 YP_001305870.1 CDS Tmel_0621 NC_009616.1 663417 664736 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(663417..664736) Thermosipho melanesiensis BI429 5296996 YP_001305871.1 CDS Tmel_0622 NC_009616.1 664975 665775 D PFAM: flagellin domain protein; flagellin domain-containing protein 664975..665775 Thermosipho melanesiensis BI429 5296739 YP_001305872.1 CDS Tmel_0623 NC_009616.1 665942 666445 R PFAM: NUDIX hydrolase; NUDIX hydrolase complement(665942..666445) Thermosipho melanesiensis BI429 5298143 YP_001305873.1 CDS Tmel_0624 NC_009616.1 666447 667073 R PFAM: Haloacid dehalogenase domain protein hydrolase; hydrolase complement(666447..667073) Thermosipho melanesiensis BI429 5297313 YP_001305874.1 CDS Tmel_0625 NC_009616.1 667118 667477 D PFAM: protein of unknown function DUF123; hypothetical protein 667118..667477 Thermosipho melanesiensis BI429 5296984 YP_001305875.1 CDS clpX NC_009616.1 667575 668801 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 667575..668801 Thermosipho melanesiensis BI429 5296985 YP_001305876.1 CDS Tmel_0627 NC_009616.1 668802 669779 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 668802..669779 Thermosipho melanesiensis BI429 5296750 YP_001305877.1 CDS Tmel_0628 NC_009616.1 669769 670692 R PFAM: CBS domain containing protein; ATP-binding region, ATPase domain protein domain protein; signal transduction protein complement(669769..670692) Thermosipho melanesiensis BI429 5297587 YP_001305878.1 CDS Tmel_0629 NC_009616.1 670738 671589 R TIGRFAM: HflC protein; PFAM: band 7 protein; HflC protein complement(670738..671589) Thermosipho melanesiensis BI429 5297588 YP_001305879.1 CDS Tmel_0630 NC_009616.1 671586 672515 R TIGRFAM: HflK protein; PFAM: band 7 protein; HflK protein complement(671586..672515) Thermosipho melanesiensis BI429 5297013 YP_001305880.1 CDS Tmel_0631 NC_009616.1 672555 673064 R PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; rubrerythrin complement(672555..673064) Thermosipho melanesiensis BI429 5297014 YP_001305881.1 CDS Tmel_0632 NC_009616.1 673090 675075 R glycine--tRNA ligase complement(673090..675075) Thermosipho melanesiensis BI429 5297369 YP_001305882.1 CDS glyQ NC_009616.1 675075 675926 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(675075..675926) Thermosipho melanesiensis BI429 5297275 YP_001305883.1 CDS Tmel_0634 NC_009616.1 675940 676575 R hypothetical protein complement(675940..676575) Thermosipho melanesiensis BI429 5297276 YP_001305884.1 CDS Tmel_0635 NC_009616.1 676575 677639 R PFAM: cell cycle protein; cell cycle protein complement(676575..677639) Thermosipho melanesiensis BI429 5297153 YP_001305885.1 CDS rpsF NC_009616.1 677988 678347 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 677988..678347 Thermosipho melanesiensis BI429 5298183 YP_001305886.1 CDS Tmel_0637 NC_009616.1 678344 678745 D TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; single-strand binding protein 678344..678745 Thermosipho melanesiensis BI429 5297490 YP_001305887.1 CDS rpsR NC_009616.1 678768 678995 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 678768..678995 Thermosipho melanesiensis BI429 5297761 YP_001305888.1 CDS rpmG NC_009616.1 679233 679382 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 679233..679382 Thermosipho melanesiensis BI429 5298414 YP_001305889.1 CDS Tmel_0640 NC_009616.1 679490 679678 D TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; preprotein translocase subunit SecE 679490..679678 Thermosipho melanesiensis BI429 5298083 YP_001305890.1 CDS Tmel_0641 NC_009616.1 679697 680767 D TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein; NusG antitermination factor 679697..680767 Thermosipho melanesiensis BI429 5297352 YP_001305891.1 CDS rplK NC_009616.1 680814 681239 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 680814..681239 Thermosipho melanesiensis BI429 5297283 YP_001305892.1 CDS rplA NC_009616.1 681266 681964 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 681266..681964 Thermosipho melanesiensis BI429 5296661 YP_001305893.1 CDS Tmel_0644 NC_009616.1 682001 682750 R PFAM: protein of unknown function DUF368; hypothetical protein complement(682001..682750) Thermosipho melanesiensis BI429 5296662 YP_001305894.1 CDS Tmel_0645 NC_009616.1 683202 684194 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(683202..684194) Thermosipho melanesiensis BI429 5298373 YP_001305895.1 CDS Tmel_0646 NC_009616.1 684379 684867 D PFAM: dihydrofolate reductase region; dihydrofolate reductase region 684379..684867 Thermosipho melanesiensis BI429 5297354 YP_001305896.1 CDS Tmel_0647 NC_009616.1 684859 685308 R hypothetical protein complement(684859..685308) Thermosipho melanesiensis BI429 5297690 YP_001305897.1 CDS Tmel_0648 NC_009616.1 685321 686418 R PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD-binding subunit complement(685321..686418) Thermosipho melanesiensis BI429 5297952 YP_001305898.1 CDS Tmel_0649 NC_009616.1 686428 687018 R PFAM: RnfA-Nqr electron transport subunit; RnfA-Nqr electron transport subunit complement(686428..687018) Thermosipho melanesiensis BI429 5297953 YP_001305899.1 CDS Tmel_0650 NC_009616.1 687011 687607 R PFAM: RnfA-Nqr electron transport subunit; RnfA-Nqr electron transport subunit complement(687011..687607) Thermosipho melanesiensis BI429 5297491 YP_001305900.1 CDS Tmel_0651 NC_009616.1 687600 688211 R PFAM: FMN-binding domain protein; FMN-binding domain-containing protein complement(687600..688211) Thermosipho melanesiensis BI429 5297492 YP_001305901.1 CDS Tmel_0652 NC_009616.1 688208 689095 R PFAM: NQR2 and RnfD family protein; NQR2 and RnfD family protein complement(688208..689095) Thermosipho melanesiensis BI429 5296551 YP_001305902.1 CDS Tmel_0653 NC_009616.1 689202 690239 R PFAM: Nucleotidyl transferase; mannose-1-phosphate guanylyltransferase (GDP) complement(689202..690239) Thermosipho melanesiensis BI429 5297800 YP_001305903.1 CDS Tmel_0654 NC_009616.1 690258 691211 R PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; Electron transfer flavoprotein, alpha subunit-like; electron transfer flavoprotein subunit alpha-like protein complement(690258..691211) Thermosipho melanesiensis BI429 5297801 YP_001305904.1 CDS Tmel_0655 NC_009616.1 691219 691998 R PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; electron transfer flavoprotein, alpha/beta-subunit-like protein complement(691219..691998) Thermosipho melanesiensis BI429 5296627 YP_001305905.1 CDS Tmel_0656 NC_009616.1 692003 693145 R PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; acyl-CoA dehydrogenase domain-containing protein complement(692003..693145) Thermosipho melanesiensis BI429 5296628 YP_001305906.1 CDS Tmel_0657 NC_009616.1 693408 694937 D PFAM: protein of unknown function DUF342; hypothetical protein 693408..694937 Thermosipho melanesiensis BI429 5297096 YP_001305907.1 CDS Tmel_0658 NC_009616.1 694934 696595 D hypothetical protein 694934..696595 Thermosipho melanesiensis BI429 5297381 YP_001305908.1 CDS Tmel_0659 NC_009616.1 696625 698640 R PFAM: lipopolysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein complement(696625..698640) Thermosipho melanesiensis BI429 5297382 YP_001305909.1 CDS Tmel_0660 NC_009616.1 698656 701127 R PFAM: polysaccharide export protein; polysaccharide export protein complement(698656..701127) Thermosipho melanesiensis BI429 5297235 YP_001305910.1 CDS Tmel_0661 NC_009616.1 701201 702076 D PFAM: phosphoesterase, RecJ domain protein; phosphoesterase domain-containing protein 701201..702076 Thermosipho melanesiensis BI429 5297236 YP_001305911.1 CDS Tmel_0662 NC_009616.1 702081 702884 D PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; phosphotransferase domain-containing protein 702081..702884 Thermosipho melanesiensis BI429 5297359 YP_001305912.1 CDS Tmel_0663 NC_009616.1 702958 704433 D TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramyl-tripeptide synthetase 702958..704433 Thermosipho melanesiensis BI429 5296956 YP_001305913.1 CDS Tmel_0664 NC_009616.1 704430 704777 D hypothetical protein 704430..704777 Thermosipho melanesiensis BI429 5296957 YP_001305914.1 CDS mraY NC_009616.1 704840 705646 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 704840..705646 Thermosipho melanesiensis BI429 5297211 YP_001305915.1 CDS Tmel_0666 NC_009616.1 705651 706487 D PFAM: glycosyl transferase, family 4; glycosyl transferase family protein 705651..706487 Thermosipho melanesiensis BI429 5297212 YP_001305916.1 CDS Tmel_0667 NC_009616.1 706489 706755 R hypothetical protein complement(706489..706755) Thermosipho melanesiensis BI429 5297291 YP_001305917.1 CDS flgI NC_009616.1 706766 707755 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(706766..707755) Thermosipho melanesiensis BI429 5297071 YP_001305918.1 CDS Tmel_0669 NC_009616.1 707766 708350 R flagellar basal body L-ring protein-like protein complement(707766..708350) Thermosipho melanesiensis BI429 5297072 YP_001305919.1 CDS Tmel_0670 NC_009616.1 708347 709279 R flagellar basal body P-ring biosynthesis protein-like protein complement(708347..709279) Thermosipho melanesiensis BI429 5296798 YP_001305920.1 CDS Tmel_0671 NC_009616.1 709281 711164 R TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II; DNA gyrase subunit B complement(709281..711164) Thermosipho melanesiensis BI429 5296799 YP_001305921.1 CDS Tmel_0672 NC_009616.1 711154 711456 R hypothetical protein complement(711154..711456) Thermosipho melanesiensis BI429 5296660 YP_001305922.1 CDS Tmel_0673 NC_009616.1 711431 712174 R PFAM: aminotransferase, class IV; class IV aminotransferase complement(711431..712174) Thermosipho melanesiensis BI429 5296794 YP_001305923.1 CDS Tmel_0674 NC_009616.1 712149 713438 R TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein complement(712149..713438) Thermosipho melanesiensis BI429 5296795 YP_001305924.1 CDS Tmel_0675 NC_009616.1 713440 713883 R PFAM: CBS domain containing protein; signal transduction protein complement(713440..713883) Thermosipho melanesiensis BI429 5297284 YP_001305925.1 CDS Tmel_0676 NC_009616.1 713885 714838 R PFAM: PfkB domain protein; ribokinase-like domain-containing protein complement(713885..714838) Thermosipho melanesiensis BI429 5297285 YP_001305926.1 CDS Tmel_0677 NC_009616.1 714844 715563 R cobalamin/Fe3+-siderophores ABC transporter ATPase-like protein complement(714844..715563) Thermosipho melanesiensis BI429 5297084 YP_001305927.1 CDS Tmel_0678 NC_009616.1 715919 716494 R hypothetical protein complement(715919..716494) Thermosipho melanesiensis BI429 5297530 YP_001305928.1 CDS Tmel_0679 NC_009616.1 716506 719274 R hypothetical protein complement(716506..719274) Thermosipho melanesiensis BI429 5297531 YP_001305929.1 CDS Tmel_0680 NC_009616.1 719290 720822 R hypothetical protein complement(719290..720822) Thermosipho melanesiensis BI429 5296607 YP_001305930.1 CDS Tmel_0681 NC_009616.1 720892 722004 R PFAM: Radical SAM domain protein; radical SAM domain-containing protein complement(720892..722004) Thermosipho melanesiensis BI429 5296608 YP_001305931.1 CDS Tmel_0682 NC_009616.1 722087 724312 D TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; heavy metal translocating P-type ATPase 722087..724312 Thermosipho melanesiensis BI429 5296734 YP_001305932.1 CDS Tmel_0683 NC_009616.1 724324 724545 D hypothetical protein 724324..724545 Thermosipho melanesiensis BI429 5297728 YP_001305933.1 CDS Tmel_0684 NC_009616.1 724550 724744 D hypothetical protein 724550..724744 Thermosipho melanesiensis BI429 5297729 YP_001305934.1 CDS Tmel_0685 NC_009616.1 724757 724963 D PFAM: Heavy metal transport/detoxification protein; heavy metal transport/detoxification protein 724757..724963 Thermosipho melanesiensis BI429 5296633 YP_001305935.1 CDS glyA NC_009616.1 724989 726263 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(724989..726263) Thermosipho melanesiensis BI429 5296634 YP_001305936.1 CDS Tmel_0687 NC_009616.1 726630 727046 D hypothetical protein 726630..727046 Thermosipho melanesiensis BI429 5297207 YP_001305937.1 CDS Tmel_0688 NC_009616.1 727197 728225 D PFAM: ROK family protein; ROK family protein 727197..728225 Thermosipho melanesiensis BI429 5296569 YP_001305938.1 CDS Tmel_0689 NC_009616.1 728218 729549 D PFAM: glycoside hydrolase, family 3 domain protein; glycoside hydrolase family 3 protein 728218..729549 Thermosipho melanesiensis BI429 5296570 YP_001305939.1 CDS Tmel_0690 NC_009616.1 729546 730754 D PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 729546..730754 Thermosipho melanesiensis BI429 5297232 YP_001305940.1 CDS Tmel_0691 NC_009616.1 730791 731678 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 730791..731678 Thermosipho melanesiensis BI429 5297233 YP_001305941.1 CDS Tmel_0692 NC_009616.1 731675 732847 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 731675..732847 Thermosipho melanesiensis BI429 5297161 YP_001305942.1 CDS Tmel_0693 NC_009616.1 732844 733752 D PFAM: sugar isomerase (SIS); sugar isomerase (SIS) 732844..733752 Thermosipho melanesiensis BI429 5297308 YP_001305943.1 CDS Tmel_0694 NC_009616.1 733763 734812 D PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 733763..734812 Thermosipho melanesiensis BI429 5297309 YP_001305944.1 CDS Tmel_0695 NC_009616.1 735101 736129 D PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 735101..736129 Thermosipho melanesiensis BI429 5297331 YP_001305945.1 CDS Tmel_0696 NC_009616.1 736126 736464 D PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; cobalamin (vitamin B12) biosynthesis CbiX protein 736126..736464 Thermosipho melanesiensis BI429 5297332 YP_001305946.1 CDS Tmel_0697 NC_009616.1 736461 737078 D PFAM: Precorrin-8X methylmutase CbiC/CobH; precorrin-8X methylmutase CbiC/CobH 736461..737078 Thermosipho melanesiensis BI429 5297147 YP_001305947.1 CDS cbiD NC_009616.1 737071 738129 D Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 737071..738129 Thermosipho melanesiensis BI429 5296541 YP_001305948.1 CDS Tmel_0699 NC_009616.1 738098 738685 D TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-6Y C5,15-methyltransferase subunit CbiE 738098..738685 Thermosipho melanesiensis BI429 5296542 YP_001305949.1 CDS Tmel_0700 NC_009616.1 738690 739229 D TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6Y C5,15-methyltransferase subunit CbiT 738690..739229 Thermosipho melanesiensis BI429 5296516 YP_001305950.1 CDS Tmel_0701 NC_009616.1 739226 739861 D PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 739226..739861 Thermosipho melanesiensis BI429 5296517 YP_001305951.1 CDS Tmel_0702 NC_009616.1 739862 740596 D TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; precorrin-4 C11-methyltransferase 739862..740596 Thermosipho melanesiensis BI429 5296813 YP_001305952.1 CDS Tmel_0703 NC_009616.1 740593 741555 D catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; cobalamin biosynthesis protein CbiG 740593..741555 Thermosipho melanesiensis BI429 5297632 YP_001305953.1 CDS Tmel_0704 NC_009616.1 741557 742264 D PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; uroporphyrin-III C/tetrapyrrole methyltransferase 741557..742264 Thermosipho melanesiensis BI429 5297633 YP_001305954.1 CDS Tmel_0705 NC_009616.1 742261 743001 D TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; precorrin-6x reductase 742261..743001 Thermosipho melanesiensis BI429 5297065 YP_001305955.1 CDS Tmel_0706 NC_009616.1 742973 744079 D PFAM: glutamyl-tRNA reductase; Shikimate/quinate 5-dehydrogenase; glutamyl-tRNA reductase 742973..744079 Thermosipho melanesiensis BI429 5297066 YP_001305956.1 CDS Tmel_0707 NC_009616.1 744076 744915 D TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; porphobilinogen deaminase 744076..744915 Thermosipho melanesiensis BI429 5297105 YP_001305957.1 CDS Tmel_0708 NC_009616.1 744906 746300 D TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; uroporphyrin-III C-methyltransferase 744906..746300 Thermosipho melanesiensis BI429 5296896 YP_001305958.1 CDS Tmel_0709 NC_009616.1 746272 747219 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 746272..747219 Thermosipho melanesiensis BI429 5296897 YP_001305959.1 CDS Tmel_0710 NC_009616.1 747201 747647 D siroheme synthase 747201..747647 Thermosipho melanesiensis BI429 5297750 YP_001305960.1 CDS Tmel_0711 NC_009616.1 747640 748911 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 747640..748911 Thermosipho melanesiensis BI429 5297751 YP_001305961.1 CDS Tmel_0712 NC_009616.1 748908 749615 D TIGRFAM: cobalamin biosynthesis protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; cobalamin biosynthesis protein CbiM 748908..749615 Thermosipho melanesiensis BI429 5296964 YP_001305962.1 CDS Tmel_0713 NC_009616.1 749615 749896 D TIGRFAM: cobalt transport protein; PFAM: Cobalt transport protein CbiN; cobalt transport protein 749615..749896 Thermosipho melanesiensis BI429 5297473 YP_001305963.1 CDS Tmel_0714 NC_009616.1 749886 750566 D PFAM: cobalt transport protein; cobalt transport protein 749886..750566 Thermosipho melanesiensis BI429 5297474 YP_001305964.1 CDS Tmel_0715 NC_009616.1 750563 751276 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 750563..751276 Thermosipho melanesiensis BI429 5297936 YP_001305965.1 CDS Tmel_0716 NC_009616.1 751273 751905 D TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71, ATP-binding region; putative ATP binding protein 751273..751905 Thermosipho melanesiensis BI429 5297937 YP_001305966.1 CDS Tmel_0717 NC_009616.1 751923 752585 R PFAM: ribonuclease H; ribonuclease H complement(751923..752585) Thermosipho melanesiensis BI429 5297150 YP_001305967.1 CDS guaA NC_009616.1 752614 754155 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(752614..754155) Thermosipho melanesiensis BI429 5296922 YP_001305968.1 CDS Tmel_0719 NC_009616.1 754288 754437 R hypothetical protein complement(754288..754437) Thermosipho melanesiensis BI429 5296923 YP_001305969.1 CDS Tmel_0720 NC_009616.1 758672 759223 R PFAM: LemA family protein; LemA family protein complement(758672..759223) Thermosipho melanesiensis BI429 5297880 YP_001305970.1 CDS Tmel_0721 NC_009616.1 759247 760968 R hypothetical protein complement(759247..760968) Thermosipho melanesiensis BI429 5297881 YP_001305971.1 CDS Tmel_0722 NC_009616.1 760981 761133 R hypothetical protein complement(760981..761133) Thermosipho melanesiensis BI429 5297859 YP_001305972.1 CDS Tmel_0723 NC_009616.1 761181 761783 R PFAM: putative esterase; putative esterase complement(761181..761783) Thermosipho melanesiensis BI429 5297106 YP_001305973.1 CDS Tmel_0724 NC_009616.1 761765 762040 R hypothetical protein complement(761765..762040) Thermosipho melanesiensis BI429 5297107 YP_001305974.1 CDS Tmel_0725 NC_009616.1 762071 763327 R catalyzes the formation of L-tryptophan from indole and L-serine; tryptophan synthase subunit beta complement(762071..763327) Thermosipho melanesiensis BI429 5297807 YP_001305975.1 CDS Tmel_0726 NC_009616.1 763556 764476 R PFAM: phosphate transporter; phosphate transporter complement(763556..764476) Thermosipho melanesiensis BI429 5297808 YP_001305976.1 CDS Tmel_0727 NC_009616.1 764600 766135 R hypothetical protein complement(764600..766135) Thermosipho melanesiensis BI429 5297864 YP_001305977.1 CDS Tmel_0728 NC_009616.1 766260 766808 R PFAM: nitroreductase; nitroreductase complement(766260..766808) Thermosipho melanesiensis BI429 5296493 YP_001305978.1 CDS Tmel_0729 NC_009616.1 766813 769158 R PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; homocysteine S-methyltransferase complement(766813..769158) Thermosipho melanesiensis BI429 5296494 YP_001305979.1 CDS Tmel_0730 NC_009616.1 769137 769673 R PFAM: Vitamin B12 dependent methionine synthase, activation region; vitamin B12 dependent methionine synthase, activation region complement(769137..769673) Thermosipho melanesiensis BI429 5297122 YP_001305980.1 CDS Tmel_0731 NC_009616.1 769682 770599 R PFAM: methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H) complement(769682..770599) Thermosipho melanesiensis BI429 5297123 YP_001305981.1 CDS Tmel_0732 NC_009616.1 770601 771314 R hypothetical protein complement(770601..771314) Thermosipho melanesiensis BI429 5297631 YP_001305982.1 CDS Tmel_0733 NC_009616.1 771296 772600 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF39; hypothetical protein complement(771296..772600) Thermosipho melanesiensis BI429 5298457 YP_001305983.1 CDS Tmel_0734 NC_009616.1 772597 773739 R PFAM: aspartate/glutamate/uridylate kinase; aspartate kinase complement(772597..773739) Thermosipho melanesiensis BI429 5298458 YP_001305984.1 CDS Tmel_0736 NC_009616.1 775390 777837 D PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 775390..777837 Thermosipho melanesiensis BI429 5298079 YP_001305985.1 CDS Tmel_0737 NC_009616.1 778015 779085 R hypothetical protein complement(778015..779085) Thermosipho melanesiensis BI429 5297573 YP_001305986.1 CDS Tmel_0738 NC_009616.1 779334 779804 R PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen complement(779334..779804) Thermosipho melanesiensis BI429 5297249 YP_001305987.1 CDS Tmel_0739 NC_009616.1 779814 781301 R hypothetical protein complement(779814..781301) Thermosipho melanesiensis BI429 5297526 YP_001305988.1 CDS Tmel_0740 NC_009616.1 781314 782057 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(781314..782057) Thermosipho melanesiensis BI429 5297527 YP_001305989.1 CDS Tmel_0741 NC_009616.1 782032 782679 R hypothetical protein complement(782032..782679) Thermosipho melanesiensis BI429 5297566 YP_001305990.1 CDS Tmel_0742 NC_009616.1 782676 783209 R putative transcriptional regulator complement(782676..783209) Thermosipho melanesiensis BI429 5297567 YP_001305991.1 CDS Tmel_0743 NC_009616.1 783257 783541 R hypothetical protein complement(783257..783541) Thermosipho melanesiensis BI429 5297831 YP_001305992.1 CDS hisS NC_009616.1 783538 784797 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(783538..784797) Thermosipho melanesiensis BI429 5297441 YP_001305993.1 CDS Tmel_0745 NC_009616.1 784782 785480 R SMART: Tetratricopeptide domain protein; tetratricopeptide domain-containing protein complement(784782..785480) Thermosipho melanesiensis BI429 5297442 YP_001305994.1 CDS Tmel_0746 NC_009616.1 785455 786276 R TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3; Cof-like hydrolase complement(785455..786276) Thermosipho melanesiensis BI429 5297612 YP_001305995.1 CDS Tmel_0747 NC_009616.1 786282 787361 R TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidyltransferase complement(786282..787361) Thermosipho melanesiensis BI429 5297613 YP_001305996.1 CDS Tmel_0748 NC_009616.1 787383 787916 R hypothetical protein complement(787383..787916) Thermosipho melanesiensis BI429 5297882 YP_001305997.1 CDS Tmel_0749 NC_009616.1 788205 790178 D PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer 788205..790178 Thermosipho melanesiensis BI429 5298218 YP_001305998.1 CDS Tmel_0750 NC_009616.1 790286 792745 D TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 790286..792745 Thermosipho melanesiensis BI429 5298219 YP_001305999.1 CDS Tmel_0751 NC_009616.1 792856 793689 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(792856..793689) Thermosipho melanesiensis BI429 5298149 YP_001306000.1 CDS Tmel_0752 NC_009616.1 793699 794565 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(793699..794565) Thermosipho melanesiensis BI429 5298150 YP_001306001.1 CDS Tmel_0753 NC_009616.1 794607 795920 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(794607..795920) Thermosipho melanesiensis BI429 5298148 YP_001306002.1 CDS Tmel_0754 NC_009616.1 796144 797802 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(796144..797802) Thermosipho melanesiensis BI429 5298104 YP_001306003.1 CDS Tmel_0755 NC_009616.1 797815 799011 R PFAM: Hemerythrin HHE cation binding domain protein; hemerythrin HHE cation binding domain-containing protein complement(797815..799011) Thermosipho melanesiensis BI429 5298105 YP_001306004.1 CDS Tmel_0756 NC_009616.1 799102 799764 R PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; CRP/FNR family transcriptional regulator complement(799102..799764) Thermosipho melanesiensis BI429 5298073 YP_001306005.1 CDS Tmel_0757 NC_009616.1 799803 801527 R PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/subunit complement(799803..801527) Thermosipho melanesiensis BI429 5298074 YP_001306006.1 CDS Tmel_0758 NC_009616.1 801532 801903 R PFAM: CoA-binding domain protein; CoA-binding domain-containing protein complement(801532..801903) Thermosipho melanesiensis BI429 5298450 YP_001306007.1 CDS Tmel_0759 NC_009616.1 801999 802463 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen 801999..802463 Thermosipho melanesiensis BI429 5298341 YP_001306008.1 CDS Tmel_0760 NC_009616.1 802472 803308 D TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; PhzF family phenazine biosynthesis protein 802472..803308 Thermosipho melanesiensis BI429 5298342 YP_001306009.1 CDS Tmel_0761 NC_009616.1 803339 804370 R PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; mandelate racemase/muconate lactonizing protein complement(803339..804370) Thermosipho melanesiensis BI429 5298051 YP_001306010.1 CDS Tmel_0762 NC_009616.1 804383 804991 R TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15, pyroglutamyl peptidase I; pyrrolidone-carboxylate peptidase complement(804383..804991) Thermosipho melanesiensis BI429 5298052 YP_001306011.1 CDS Tmel_0763 NC_009616.1 805155 806117 D PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI 805155..806117 Thermosipho melanesiensis BI429 5298307 YP_001306012.1 CDS Tmel_0764 NC_009616.1 806131 807015 D PFAM: glycosidase, PH1107-related; glycosidase 806131..807015 Thermosipho melanesiensis BI429 5298343 YP_001306013.1 CDS Tmel_0765 NC_009616.1 807020 808444 D PFAM: glycoside hydrolase, family 4; glycoside hydrolase family protein 807020..808444 Thermosipho melanesiensis BI429 5298344 YP_001306014.1 CDS Tmel_0766 NC_009616.1 808601 808807 D PFAM: regulatory protein, ArsR; regulatory protein ArsR 808601..808807 Thermosipho melanesiensis BI429 5298043 YP_001306015.1 CDS Tmel_0768 NC_009616.1 809902 810681 D TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 809902..810681 Thermosipho melanesiensis BI429 5298080 YP_001306016.1 CDS Tmel_0769 NC_009616.1 810678 812333 R TIGRFAM: DNA mismatch repair protein MutL; PFAM: DNA mismatch repair protein, C-terminal domain protein; MutL, C-terminal, dimerisation; DNA mismatch repair protein MutL complement(810678..812333) Thermosipho melanesiensis BI429 5298311 YP_001306017.1 CDS Tmel_0770 NC_009616.1 812334 813701 R PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit complement(812334..813701) Thermosipho melanesiensis BI429 5298056 YP_001306018.1 CDS Tmel_0771 NC_009616.1 813703 814170 R TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase complement(813703..814170) Thermosipho melanesiensis BI429 5298057 YP_001306019.1 CDS Tmel_0772 NC_009616.1 814183 815409 R TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(814183..815409) Thermosipho melanesiensis BI429 5298420 YP_001306020.1 CDS Tmel_0773 NC_009616.1 815413 816384 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(815413..816384) Thermosipho melanesiensis BI429 5298421 YP_001306021.1 CDS Tmel_0774 NC_009616.1 816377 817924 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(816377..817924) Thermosipho melanesiensis BI429 5298137 YP_001306022.1 CDS Tmel_0775 NC_009616.1 817902 818621 R hypothetical protein complement(817902..818621) Thermosipho melanesiensis BI429 5297988 YP_001306023.1 CDS Tmel_0776 NC_009616.1 818634 818930 R hypothetical protein complement(818634..818930) Thermosipho melanesiensis BI429 5297989 YP_001306024.1 CDS Tmel_0777 NC_009616.1 818927 819538 R TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; ECF subfamily RNA polymerase sigma-24 factor complement(818927..819538) Thermosipho melanesiensis BI429 5298071 YP_001306025.1 CDS Tmel_0778 NC_009616.1 819519 820271 R PFAM: protein of unknown function DUF72; hypothetical protein complement(819519..820271) Thermosipho melanesiensis BI429 5298072 YP_001306026.1 CDS Tmel_0779 NC_009616.1 820268 822160 R PFAM: UvrD/REP helicase; UvrD/REP helicase complement(820268..822160) Thermosipho melanesiensis BI429 5297987 YP_001306027.1 CDS Tmel_0780 NC_009616.1 822534 822974 R hypothetical protein complement(822534..822974) Thermosipho melanesiensis BI429 5298273 YP_001306028.1 CDS Tmel_0781 NC_009616.1 822979 823620 R hypothetical protein complement(822979..823620) Thermosipho melanesiensis BI429 5298274 YP_001306029.1 CDS Tmel_0782 NC_009616.1 823633 824616 R PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI complement(823633..824616) Thermosipho melanesiensis BI429 5298402 YP_001306030.1 CDS Tmel_0783 NC_009616.1 824613 825818 R TIGRFAM: molybdenum cofactor synthesis domain; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; competence/damage-inducible protein CinA complement(824613..825818) Thermosipho melanesiensis BI429 5298403 YP_001306031.1 CDS pyrG NC_009616.1 825951 827528 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 825951..827528 Thermosipho melanesiensis BI429 5298394 YP_001306032.1 CDS Tmel_0785 NC_009616.1 827525 828247 D TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP C-terminal domain protein; HisJ family histidinol phosphate phosphatase 827525..828247 Thermosipho melanesiensis BI429 5298364 YP_001306033.1 CDS tsf NC_009616.1 828244 828834 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 828244..828834 Thermosipho melanesiensis BI429 5298365 YP_001306034.1 CDS Tmel_0787 NC_009616.1 829042 830112 R TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; putative PAS/PAC sensor protein complement(829042..830112) Thermosipho melanesiensis BI429 5298053 YP_001306035.1 CDS Tmel_0788 NC_009616.1 830117 830755 R PFAM: protein of unknown function DUF47; hypothetical protein complement(830117..830755) Thermosipho melanesiensis BI429 5298054 YP_001306036.1 CDS Tmel_0789 NC_009616.1 830775 831701 R PFAM: phosphate transporter; phosphate transporter complement(830775..831701) Thermosipho melanesiensis BI429 5298109 YP_001306037.1 CDS Tmel_0790 NC_009616.1 831820 832536 D hypothetical protein 831820..832536 Thermosipho melanesiensis BI429 5298087 YP_001306038.1 CDS Tmel_0791 NC_009616.1 832549 832695 D hypothetical protein 832549..832695 Thermosipho melanesiensis BI429 5298088 YP_001306039.1 CDS Tmel_0792 NC_009616.1 832698 833237 D hypothetical protein 832698..833237 Thermosipho melanesiensis BI429 5298097 YP_001306040.1 CDS Tmel_0793 NC_009616.1 833248 834165 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 833248..834165 Thermosipho melanesiensis BI429 5298098 YP_001306041.1 CDS Tmel_0794 NC_009616.1 834197 834802 R Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.; indolepyruvate oxidoreductase subunit beta complement(834197..834802) Thermosipho melanesiensis BI429 5298084 YP_001306042.1 CDS Tmel_0795 NC_009616.1 834802 836730 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate binding domain-containing protein complement(834802..836730) Thermosipho melanesiensis BI429 5298040 YP_001306043.1 CDS Tmel_0796 NC_009616.1 836968 838242 D PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter 836968..838242 Thermosipho melanesiensis BI429 5298041 YP_001306044.1 CDS Tmel_0797 NC_009616.1 838245 839318 D PFAM: GTP-binding protein, HSR1-related; HSR1-like GTP-binding protein 838245..839318 Thermosipho melanesiensis BI429 5298230 YP_001306045.1 CDS Tmel_0798 NC_009616.1 839322 839909 D PFAM: Propanediol utilization protein; propanediol utilization protein 839322..839909 Thermosipho melanesiensis BI429 5298231 YP_001306046.1 CDS Tmel_0799 NC_009616.1 840017 840214 D hypothetical protein 840017..840214 Thermosipho melanesiensis BI429 5298215 YP_001306047.1 CDS Tmel_0800 NC_009616.1 840235 840504 D hypothetical protein 840235..840504 Thermosipho melanesiensis BI429 5298008 YP_001306048.1 CDS Tmel_0801 NC_009616.1 840516 840647 D hypothetical protein 840516..840647 Thermosipho melanesiensis BI429 5298009 YP_001306049.1 CDS Tmel_0803 NC_009616.1 840893 844381 R PFAM: glycoside hydrolase, family 13 domain protein; glycoside hydrolase, family 57; glycoside hydrolase family protein complement(840893..844381) Thermosipho melanesiensis BI429 5298102 YP_001306050.1 CDS Tmel_0804 NC_009616.1 844465 844788 R PFAM: NADH-ubiquinone oxidoreductase, chain 4L; NADH-ubiquinone oxidoreductase subunit 4L complement(844465..844788) Thermosipho melanesiensis BI429 5298284 YP_001306051.1 CDS Tmel_0805 NC_009616.1 844782 845987 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH/ubiquinone/plastoquinone (complex I) complement(844782..845987) Thermosipho melanesiensis BI429 5298099 YP_001306052.1 CDS Tmel_0806 NC_009616.1 846071 847255 R PFAM: phosphofructokinase; phosphofructokinase complement(846071..847255) Thermosipho melanesiensis BI429 5298220 YP_001306053.1 CDS Tmel_0807 NC_009616.1 847321 848460 R PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(847321..848460) Thermosipho melanesiensis BI429 5298221 YP_001306054.1 CDS era NC_009616.1 848465 849364 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(848465..849364) Thermosipho melanesiensis BI429 5298223 YP_001306055.1 CDS pheT NC_009616.1 849366 851702 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(849366..851702) Thermosipho melanesiensis BI429 5298224 YP_001306056.1 CDS Tmel_0810 NC_009616.1 851721 852338 R hypothetical protein complement(851721..852338) Thermosipho melanesiensis BI429 5298226 YP_001306057.1 CDS Tmel_0811 NC_009616.1 852340 852759 R PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Sel1 domain protein repeat-containing protein; Tetratricopeptide domain protein; TPR repeat-containing protein complement(852340..852759) Thermosipho melanesiensis BI429 5298227 YP_001306058.1 CDS Tmel_0812 NC_009616.1 852734 854221 R hypothetical protein complement(852734..854221) Thermosipho melanesiensis BI429 5298138 YP_001306059.1 CDS Tmel_0813 NC_009616.1 854218 854820 R PFAM: protein of unknown function DUF205; membrane protein complement(854218..854820) Thermosipho melanesiensis BI429 5298139 YP_001306060.1 CDS Tmel_0814 NC_009616.1 854820 855620 R hypothetical protein complement(854820..855620) Thermosipho melanesiensis BI429 5298028 YP_001306061.1 CDS Tmel_0815 NC_009616.1 855648 856712 R PFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(855648..856712) Thermosipho melanesiensis BI429 5298029 YP_001306062.1 CDS Tmel_0816 NC_009616.1 856715 857788 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(856715..857788) Thermosipho melanesiensis BI429 5298066 YP_001306063.1 CDS Tmel_0817 NC_009616.1 857791 858096 R hypothetical protein complement(857791..858096) Thermosipho melanesiensis BI429 5298067 YP_001306064.1 CDS Tmel_0818 NC_009616.1 858286 859533 D PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 858286..859533 Thermosipho melanesiensis BI429 5298119 YP_001306065.1 CDS Tmel_0819 NC_009616.1 859570 860490 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 859570..860490 Thermosipho melanesiensis BI429 5298120 YP_001306066.1 CDS Tmel_0820 NC_009616.1 860487 861296 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 860487..861296 Thermosipho melanesiensis BI429 5298173 YP_001306067.1 CDS Tmel_0821 NC_009616.1 861330 862532 D putative diguanylate cyclase 861330..862532 Thermosipho melanesiensis BI429 5298174 YP_001306068.1 CDS Tmel_0822 NC_009616.1 862593 862892 D PFAM: GGDEF domain containing protein; diguanylate cyclase 862593..862892 Thermosipho melanesiensis BI429 5298216 YP_001306069.1 CDS Tmel_0823 NC_009616.1 862893 863987 R hypothetical protein complement(862893..863987) Thermosipho melanesiensis BI429 5298217 YP_001306070.1 CDS Tmel_0824 NC_009616.1 864007 865881 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(864007..865881) Thermosipho melanesiensis BI429 5298288 YP_001306071.1 CDS Tmel_0825 NC_009616.1 866080 867420 R TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; dihydrolipoamide dehydrogenase complement(866080..867420) Thermosipho melanesiensis BI429 5298289 YP_001306072.1 CDS Tmel_0826 NC_009616.1 867478 868149 R PFAM: sugar fermentation stimulation protein; sugar fermentation stimulation protein complement(867478..868149) Thermosipho melanesiensis BI429 5298193 YP_001306073.1 CDS Tmel_0827 NC_009616.1 868194 868430 R TIGRFAM: redox-active disulfide protein 2; redox-active disulfide protein 2 complement(868194..868430) Thermosipho melanesiensis BI429 5298194 YP_001306074.1 CDS Tmel_0828 NC_009616.1 868442 869527 R PFAM: permease; permease complement(868442..869527) Thermosipho melanesiensis BI429 5298202 YP_001306075.1 CDS Tmel_0829 NC_009616.1 869604 869867 R PFAM: regulatory protein, ArsR; regulatory protein ArsR complement(869604..869867) Thermosipho melanesiensis BI429 5298203 YP_001306076.1 CDS Tmel_0830 NC_009616.1 869976 871313 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; MATE efflux family protein 869976..871313 Thermosipho melanesiensis BI429 5297996 YP_001306077.1 CDS Tmel_0831 NC_009616.1 871310 873043 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(871310..873043) Thermosipho melanesiensis BI429 5297997 YP_001306078.1 CDS Tmel_0832 NC_009616.1 873049 873453 R hypothetical protein complement(873049..873453) Thermosipho melanesiensis BI429 5298130 YP_001306079.1 CDS Tmel_0833 NC_009616.1 873957 874250 R hypothetical protein complement(873957..874250) Thermosipho melanesiensis BI429 5298131 YP_001306080.1 CDS Tmel_0834 NC_009616.1 874535 875347 D PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 874535..875347 Thermosipho melanesiensis BI429 5298263 YP_001306081.1 CDS Tmel_0835 NC_009616.1 875503 875967 D PFAM: protein of unknown function DUF327; hypothetical protein 875503..875967 Thermosipho melanesiensis BI429 5298264 YP_001306082.1 CDS Tmel_0836 NC_009616.1 875979 876746 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 875979..876746 Thermosipho melanesiensis BI429 5297993 YP_001306083.1 CDS Tmel_0837 NC_009616.1 876724 877221 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 876724..877221 Thermosipho melanesiensis BI429 5297994 YP_001306084.1 CDS Tmel_0838 NC_009616.1 877218 878762 D PFAM: helicase domain protein; DbpA, RNA-binding domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; DEAD/DEAH box helicase domain-containing protein 877218..878762 Thermosipho melanesiensis BI429 5298337 YP_001306085.1 CDS Tmel_0839 NC_009616.1 878773 879258 D PFAM: outer membrane chaperone Skp (OmpH); outer membrane chaperone Skp 878773..879258 Thermosipho melanesiensis BI429 5298338 YP_001306086.1 CDS Tmel_0840 NC_009616.1 879255 879950 D PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 879255..879950 Thermosipho melanesiensis BI429 5298349 YP_001306087.1 CDS Tmel_0841 NC_009616.1 879952 880686 D hypothetical protein 879952..880686 Thermosipho melanesiensis BI429 5298350 YP_001306088.1 CDS Tmel_0842 NC_009616.1 880679 881269 D hypothetical protein 880679..881269 Thermosipho melanesiensis BI429 5298362 YP_001306089.1 CDS Tmel_0843 NC_009616.1 881273 881641 D PFAM: response regulator receiver; response regulator receiver protein 881273..881641 Thermosipho melanesiensis BI429 5298363 YP_001306090.1 CDS Tmel_0844 NC_009616.1 881634 882998 D PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; stage II sporulation E family protein 881634..882998 Thermosipho melanesiensis BI429 5298368 YP_001306091.1 CDS Tmel_0845 NC_009616.1 883010 883567 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 883010..883567 Thermosipho melanesiensis BI429 5298369 YP_001306092.1 CDS Tmel_0846 NC_009616.1 883583 883918 D PFAM: protein of unknown function DUF322; hypothetical protein 883583..883918 Thermosipho melanesiensis BI429 5298404 YP_001306093.1 CDS nusB NC_009616.1 883919 884344 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 883919..884344 Thermosipho melanesiensis BI429 5298405 YP_001306094.1 CDS Tmel_0848 NC_009616.1 884423 884815 D hypothetical protein 884423..884815 Thermosipho melanesiensis BI429 5298121 YP_001306095.1 CDS Tmel_0849 NC_009616.1 884801 885934 R TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; flagellar biosynthetic protein FlhB complement(884801..885934) Thermosipho melanesiensis BI429 5298122 YP_001306096.1 CDS Tmel_0850 NC_009616.1 885865 886629 R TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; flagellar biosynthetic protein FliR complement(885865..886629) Thermosipho melanesiensis BI429 5298000 YP_001306097.1 CDS Tmel_0851 NC_009616.1 886629 888926 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(886629..888926) Thermosipho melanesiensis BI429 5298001 YP_001306098.1 CDS Tmel_0852 NC_009616.1 888940 889761 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(888940..889761) Thermosipho melanesiensis BI429 5298281 YP_001306099.1 CDS Tmel_0853 NC_009616.1 889800 891275 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(889800..891275) Thermosipho melanesiensis BI429 5298282 YP_001306100.1 CDS Tmel_0854 NC_009616.1 891674 892633 D PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 891674..892633 Thermosipho melanesiensis BI429 5298103 YP_001306101.1 CDS Tmel_0855 NC_009616.1 892605 893102 D PFAM: cobalbumin biosynthesis enzyme; cobalbumin biosynthesis protein 892605..893102 Thermosipho melanesiensis BI429 5298049 YP_001306102.1 CDS Tmel_0856 NC_009616.1 893099 893716 D hypothetical protein 893099..893716 Thermosipho melanesiensis BI429 5298100 YP_001306103.1 CDS Tmel_0857 NC_009616.1 893706 894404 D PFAM: cobalamin-5-phosphate synthase CobS; cobalamin-5-phosphate synthase CobS 893706..894404 Thermosipho melanesiensis BI429 5298101 YP_001306104.1 CDS Tmel_0858 NC_009616.1 894404 895801 D TIGRFAM: cobyric acid synthase CobQ; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; cobyric acid synthase CobQ 894404..895801 Thermosipho melanesiensis BI429 5298390 YP_001306105.1 CDS Tmel_0859 NC_009616.1 895785 896621 D TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; cobalamin biosynthesis protein CobD 895785..896621 Thermosipho melanesiensis BI429 5298391 YP_001306106.1 CDS Tmel_0860 NC_009616.1 896570 897541 D PFAM: aminotransferase, class I and II; putative aminotransferase 896570..897541 Thermosipho melanesiensis BI429 5298290 YP_001306107.1 CDS Tmel_0861 NC_009616.1 897538 898035 D catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 897538..898035 Thermosipho melanesiensis BI429 5298291 YP_001306108.1 CDS Tmel_0862 NC_009616.1 898193 899866 D PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 898193..899866 Thermosipho melanesiensis BI429 5298297 YP_001306109.1 CDS Tmel_0863 NC_009616.1 899941 900231 R hypothetical protein complement(899941..900231) Thermosipho melanesiensis BI429 5298298 YP_001306110.1 CDS Tmel_0864 NC_009616.1 900231 900896 R SARP family transcriptional regulator complement(900231..900896) Thermosipho melanesiensis BI429 5298436 YP_001306111.1 CDS Tmel_0865 NC_009616.1 900936 901448 R response regulator receiver/SARP domain-containing protein complement(900936..901448) Thermosipho melanesiensis BI429 5298437 YP_001306112.1 CDS glpX NC_009616.1 901732 902748 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(901732..902748) Thermosipho melanesiensis BI429 5298438 YP_001306113.1 CDS Tmel_0867 NC_009616.1 902864 903556 R PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RNA-binding S4 domain-containing protein complement(902864..903556) Thermosipho melanesiensis BI429 5298439 YP_001306114.1 CDS Tmel_0868 NC_009616.1 903543 904343 R TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS; dihydropteroate synthase complement(903543..904343) Thermosipho melanesiensis BI429 5298445 YP_001306115.1 CDS Tmel_0869 NC_009616.1 904437 905210 D esterase/lipase-like protein 904437..905210 Thermosipho melanesiensis BI429 5298446 YP_001306116.1 CDS Tmel_0870 NC_009616.1 905251 906267 D PFAM: aminotransferase, class V; class V aminotransferase 905251..906267 Thermosipho melanesiensis BI429 5298124 YP_001306117.1 CDS Tmel_0871 NC_009616.1 906264 906962 D sugar nucleotidyltransferase-like protein 906264..906962 Thermosipho melanesiensis BI429 5298125 YP_001306118.1 CDS Tmel_0872 NC_009616.1 906983 907618 D PFAM: CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase 906983..907618 Thermosipho melanesiensis BI429 5298169 YP_001306119.1 CDS Tmel_0873 NC_009616.1 907615 908580 D PFAM: conserved hypothetical protein 374; hypothetical protein 907615..908580 Thermosipho melanesiensis BI429 5298170 YP_001306120.1 CDS Tmel_0874 NC_009616.1 908581 909933 R PFAM: major facilitator superfamily MFS_1; major facilitator transporter complement(908581..909933) Thermosipho melanesiensis BI429 5298036 YP_001306121.1 CDS Tmel_0875 NC_009616.1 909930 911261 R PFAM: protein of unknown function UPF0027; hypothetical protein complement(909930..911261) Thermosipho melanesiensis BI429 5298037 YP_001306122.1 CDS Tmel_0876 NC_009616.1 911265 911921 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(911265..911921) Thermosipho melanesiensis BI429 5298095 YP_001306123.1 CDS Tmel_0877 NC_009616.1 911912 912637 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(911912..912637) Thermosipho melanesiensis BI429 5298096 YP_001306124.1 CDS Tmel_0878 NC_009616.1 912634 913533 R nitrate/sulfonate/bicarbonate ABC transporter periplasmic components-like protein complement(912634..913533) Thermosipho melanesiensis BI429 5298175 YP_001306125.1 CDS Tmel_0879 NC_009616.1 913696 914019 R hypothetical protein complement(913696..914019) Thermosipho melanesiensis BI429 5298415 YP_001306126.1 CDS Tmel_0880 NC_009616.1 914089 915252 R hypothetical protein complement(914089..915252) Thermosipho melanesiensis BI429 5298316 YP_001306127.1 CDS Tmel_0881 NC_009616.1 915255 917726 R hypothetical protein complement(915255..917726) Thermosipho melanesiensis BI429 5298317 YP_001306128.1 CDS Tmel_0882 NC_009616.1 917745 918749 R PFAM: protein of unknown function UPF0118; hypothetical protein complement(917745..918749) Thermosipho melanesiensis BI429 5298140 YP_001306129.1 CDS Tmel_0883 NC_009616.1 918739 919743 R PFAM: Asparaginase/glutaminase; asparaginase/glutaminase complement(918739..919743) Thermosipho melanesiensis BI429 5298141 YP_001306130.1 CDS Tmel_0884 NC_009616.1 919740 920441 R PFAM: Rhomboid family protein; rhomboid family protein complement(919740..920441) Thermosipho melanesiensis BI429 5298321 YP_001306131.1 CDS Tmel_0885 NC_009616.1 920457 920567 R hypothetical protein complement(920457..920567) Thermosipho melanesiensis BI429 5298322 YP_001306132.1 CDS Tmel_0886 NC_009616.1 920569 921279 R PFAM: protein of unknown function DUF218; hypothetical protein complement(920569..921279) Thermosipho melanesiensis BI429 5298162 YP_001306133.1 CDS Tmel_0887 NC_009616.1 921276 921707 R TIGRFAM: flagellar export protein FliJ; flagellar export protein FliJ complement(921276..921707) Thermosipho melanesiensis BI429 5298163 YP_001306134.1 CDS Tmel_0888 NC_009616.1 921697 922932 R hypothetical protein complement(921697..922932) Thermosipho melanesiensis BI429 5298318 YP_001306135.1 CDS Tmel_0889 NC_009616.1 922929 926390 R TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; RepA / Rep+ KID repeat-containing protein; SMCs flexible hinge domain protein; chromosome segregation protein SMC complement(922929..926390) Thermosipho melanesiensis BI429 5298319 YP_001306136.1 CDS Tmel_0890 NC_009616.1 926387 927682 R TIGRFAM: UDP-N-acetylmuramate--alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; UDP-N-acetylmuramate--alanine ligase complement(926387..927682) Thermosipho melanesiensis BI429 5297887 YP_001306137.1 CDS Tmel_0891 NC_009616.1 927679 928683 R PFAM: glycosyl transferase, family 28; Glycosyltransferase 28, C-terminal domain; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase complement(927679..928683) Thermosipho melanesiensis BI429 5297888 YP_001306138.1 CDS Tmel_0892 NC_009616.1 928676 929632 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(928676..929632) Thermosipho melanesiensis BI429 5298128 YP_001306139.1 CDS Tmel_0893 NC_009616.1 929767 930477 D PFAM: nitroreductase; nitroreductase 929767..930477 Thermosipho melanesiensis BI429 5298129 YP_001306140.1 CDS Tmel_0894 NC_009616.1 930491 932956 D hypothetical protein 930491..932956 Thermosipho melanesiensis BI429 5297682 YP_001306141.1 CDS Tmel_0895 NC_009616.1 932969 934675 D PFAM: FG-GAP repeat protein; FG-GAP repeat-containing protein 932969..934675 Thermosipho melanesiensis BI429 5297683 YP_001306142.1 CDS Tmel_0896 NC_009616.1 934677 935066 D hypothetical protein 934677..935066 Thermosipho melanesiensis BI429 5297885 YP_001306143.1 CDS Tmel_0897 NC_009616.1 935060 935548 D hypothetical protein 935060..935548 Thermosipho melanesiensis BI429 5297886 YP_001306144.1 CDS Tmel_0898 NC_009616.1 935553 936554 D hypothetical protein 935553..936554 Thermosipho melanesiensis BI429 5298020 YP_001306145.1 CDS Tmel_0899 NC_009616.1 936566 937003 D hypothetical protein 936566..937003 Thermosipho melanesiensis BI429 5298021 YP_001306146.1 CDS Tmel_0900 NC_009616.1 937000 937590 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase complement(937000..937590) Thermosipho melanesiensis BI429 5297974 YP_001306147.1 CDS Tmel_0901 NC_009616.1 937563 939494 R TIGRFAM: putative DNA helicase; SMART: DEAD-like helicases-like; putative DNA helicase complement(937563..939494) Thermosipho melanesiensis BI429 5297975 YP_001306148.1 CDS Tmel_0902 NC_009616.1 939600 939872 D hypothetical protein 939600..939872 Thermosipho melanesiensis BI429 5298134 YP_001306149.1 CDS Tmel_0903 NC_009616.1 939901 940503 D hypothetical protein 939901..940503 Thermosipho melanesiensis BI429 5298135 YP_001306150.1 CDS Tmel_0904 NC_009616.1 940541 942535 R PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; Acetyl xylan esterase; peptidase S9 prolyl oligopeptidase complement(940541..942535) Thermosipho melanesiensis BI429 5297419 YP_001306151.1 CDS Tmel_0905 NC_009616.1 942880 943929 D PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 942880..943929 Thermosipho melanesiensis BI429 5297420 YP_001306152.1 CDS Tmel_0906 NC_009616.1 943939 944247 D hypothetical protein 943939..944247 Thermosipho melanesiensis BI429 5296764 YP_001306153.1 CDS Tmel_0907 NC_009616.1 944240 945658 D PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta 944240..945658 Thermosipho melanesiensis BI429 5296765 YP_001306154.1 CDS Tmel_0908 NC_009616.1 945660 946034 D hypothetical protein 945660..946034 Thermosipho melanesiensis BI429 5297205 YP_001306155.1 CDS Tmel_0909 NC_009616.1 946027 948213 D PFAM: cobalamin B12-binding domain protein; cobalamin B12-binding domain-containing protein 946027..948213 Thermosipho melanesiensis BI429 5297206 YP_001306156.1 CDS Tmel_0910 NC_009616.1 948285 949040 D TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; TatD family hydrolase 948285..949040 Thermosipho melanesiensis BI429 5297658 YP_001306157.1 CDS Tmel_0911 NC_009616.1 949037 949606 D TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: helix-hairpin-helix motif; RuvA domain protein; DNA recombination protein RuvA, domain I; SMART: Helix-hairpin-helix DNA-binding, class 1; Holliday junction DNA helicase RuvA 949037..949606 Thermosipho melanesiensis BI429 5297659 YP_001306158.1 CDS Tmel_0912 NC_009616.1 949611 950090 D hypothetical protein 949611..950090 Thermosipho melanesiensis BI429 5297865 YP_001306159.1 CDS Tmel_0913 NC_009616.1 950104 950433 D hypothetical protein 950104..950433 Thermosipho melanesiensis BI429 5297866 YP_001306160.1 CDS Tmel_0914 NC_009616.1 950430 951128 D PFAM: PHP C-terminal domain protein; phosphotransferase domain-containing protein 950430..951128 Thermosipho melanesiensis BI429 5296802 YP_001306161.1 CDS Tmel_0915 NC_009616.1 951116 951646 D PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase 951116..951646 Thermosipho melanesiensis BI429 5296803 YP_001306162.1 CDS Tmel_0916 NC_009616.1 951649 953832 D PFAM: surface antigen (D15); surface antigen variable number repeat protein; surface antigen 951649..953832 Thermosipho melanesiensis BI429 5296489 YP_001306163.1 CDS Tmel_0917 NC_009616.1 953847 954938 D PFAM: Threonyl/alanyl tRNA synthetase, SAD; threonyl/alanyl tRNA synthetase 953847..954938 Thermosipho melanesiensis BI429 5296490 YP_001306164.1 CDS Tmel_0918 NC_009616.1 954935 956134 D hypothetical protein 954935..956134 Thermosipho melanesiensis BI429 5297960 YP_001306165.1 CDS Tmel_0919 NC_009616.1 956219 957100 D TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RluA family pseudouridine synthase 956219..957100 Thermosipho melanesiensis BI429 5297961 YP_001306166.1 CDS Tmel_0920 NC_009616.1 957102 958319 D hypothetical protein 957102..958319 Thermosipho melanesiensis BI429 5297792 YP_001306167.1 CDS Tmel_0921 NC_009616.1 958282 959559 D hypothetical protein 958282..959559 Thermosipho melanesiensis BI429 5297793 YP_001306168.1 CDS Tmel_0922 NC_009616.1 959516 960928 D TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; pyruvate kinase 959516..960928 Thermosipho melanesiensis BI429 5297701 YP_001306169.1 CDS infC NC_009616.1 961484 961909 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 961484..961909 Thermosipho melanesiensis BI429 5297980 YP_001306170.1 CDS rpmI NC_009616.1 961906 962124 D PFAM: ribosomal protein L35; 50S ribosomal protein L35 961906..962124 Thermosipho melanesiensis BI429 5296775 YP_001306171.1 CDS rplT NC_009616.1 962152 962508 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 962152..962508 Thermosipho melanesiensis BI429 5296776 YP_001306172.1 CDS rpsB NC_009616.1 962602 963375 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 962602..963375 Thermosipho melanesiensis BI429 5297001 YP_001306173.1 CDS Tmel_0927 NC_009616.1 963416 964015 D PFAM: thymidylate kinase; dTMP kinase 963416..964015 Thermosipho melanesiensis BI429 5297002 YP_001306174.1 CDS Tmel_0928 NC_009616.1 964004 964270 R TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; flagellar biosynthetic protein FliQ complement(964004..964270) Thermosipho melanesiensis BI429 5297219 YP_001306175.1 CDS fliP NC_009616.1 964273 965028 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(964273..965028) Thermosipho melanesiensis BI429 5297220 YP_001306176.1 CDS Tmel_0930 NC_009616.1 965025 965291 R hypothetical protein complement(965025..965291) Thermosipho melanesiensis BI429 5297949 YP_001306177.1 CDS Tmel_0931 NC_009616.1 965354 965716 R PFAM: response regulator receiver; response regulator receiver protein complement(965354..965716) Thermosipho melanesiensis BI429 5297950 YP_001306178.1 CDS Tmel_0932 NC_009616.1 965721 966176 R PFAM: CheW domain protein; putative CheW protein complement(965721..966176) Thermosipho melanesiensis BI429 5297217 YP_001306179.1 CDS Tmel_0933 NC_009616.1 966187 968211 R PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein; CheA signal transduction histidine kinase complement(966187..968211) Thermosipho melanesiensis BI429 5297218 YP_001306180.1 CDS Tmel_0934 NC_009616.1 968224 969615 R hypothetical protein complement(968224..969615) Thermosipho melanesiensis BI429 5297840 YP_001306181.1 CDS Tmel_0935 NC_009616.1 969612 970406 R TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; hemolysin A complement(969612..970406) Thermosipho melanesiensis BI429 5297841 YP_001306182.1 CDS Tmel_0936 NC_009616.1 970403 971626 R hypothetical protein complement(970403..971626) Thermosipho melanesiensis BI429 5297768 YP_001306183.1 CDS Tmel_0937 NC_009616.1 971626 972360 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase ACD complement(971626..972360) Thermosipho melanesiensis BI429 5297769 YP_001306184.1 CDS Tmel_0938 NC_009616.1 972357 973982 R SMART: GGDEF domain containing protein; diguanylate cyclase complement(972357..973982) Thermosipho melanesiensis BI429 5297595 YP_001306185.1 CDS Tmel_0939 NC_009616.1 974108 975301 R hypothetical protein complement(974108..975301) Thermosipho melanesiensis BI429 5297596 YP_001306186.1 CDS Tmel_0940 NC_009616.1 975298 976479 R PFAM: protein of unknown function DUF58; hypothetical protein complement(975298..976479) Thermosipho melanesiensis BI429 5296523 YP_001306187.1 CDS Tmel_0941 NC_009616.1 976479 977405 R PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; ATPase complement(976479..977405) Thermosipho melanesiensis BI429 5296524 YP_001306188.1 CDS Tmel_0942 NC_009616.1 977449 977655 R hypothetical protein complement(977449..977655) Thermosipho melanesiensis BI429 5297918 YP_001306189.1 CDS Tmel_0943 NC_009616.1 977687 978775 R PFAM: cell cycle protein; cell cycle protein complement(977687..978775) Thermosipho melanesiensis BI429 5297919 YP_001306190.1 CDS Tmel_0944 NC_009616.1 978765 979892 R TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; putative oxygen-independent coproporphyrinogen III oxidase complement(978765..979892) Thermosipho melanesiensis BI429 5297391 YP_001306191.1 CDS Tmel_0945 NC_009616.1 979861 980574 R hypothetical protein complement(979861..980574) Thermosipho melanesiensis BI429 5297392 YP_001306192.1 CDS gatB NC_009616.1 980785 982215 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(980785..982215) Thermosipho melanesiensis BI429 5297094 YP_001306193.1 CDS gatA NC_009616.1 982212 983585 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(982212..983585) Thermosipho melanesiensis BI429 5297095 YP_001306194.1 CDS rpsL NC_009616.1 984053 984427 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 984053..984427 Thermosipho melanesiensis BI429 5297674 YP_001306195.1 CDS Tmel_0949 NC_009616.1 984446 984913 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 984446..984913 Thermosipho melanesiensis BI429 5297222 YP_001306196.1 CDS Tmel_0950 NC_009616.1 984927 987002 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 984927..987002 Thermosipho melanesiensis BI429 5297568 YP_001306197.1 CDS Tmel_0951 NC_009616.1 987037 988239 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 987037..988239 Thermosipho melanesiensis BI429 5297569 YP_001306198.1 CDS rpsJ NC_009616.1 988302 988610 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 988302..988610 Thermosipho melanesiensis BI429 5296942 YP_001306199.1 CDS rplC NC_009616.1 988633 989250 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 988633..989250 Thermosipho melanesiensis BI429 5296943 YP_001306200.1 CDS rplD NC_009616.1 989288 989953 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 989288..989953 Thermosipho melanesiensis BI429 5296854 YP_001306201.1 CDS Tmel_0955 NC_009616.1 989953 990258 D PFAM: Ribosomal protein L25/L23; ribosomal protein L25/L23 989953..990258 Thermosipho melanesiensis BI429 5296855 YP_001306202.1 CDS rplB NC_009616.1 990274 991098 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 990274..991098 Thermosipho melanesiensis BI429 5296800 YP_001306203.1 CDS rpsS NC_009616.1 991114 991401 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 991114..991401 Thermosipho melanesiensis BI429 5296801 YP_001306204.1 CDS rplV NC_009616.1 991416 991865 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 991416..991865 Thermosipho melanesiensis BI429 5297372 YP_001306205.1 CDS Tmel_0959 NC_009616.1 991883 992512 D TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3-C-terminal domain protein; KH, type 2 domain protein; Ribosomal protein S3, N-terminal domain; SMART: KH domain protein; ribosomal protein S3 991883..992512 Thermosipho melanesiensis BI429 5297373 YP_001306206.1 CDS rplP NC_009616.1 992535 992963 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 992535..992963 Thermosipho melanesiensis BI429 5297910 YP_001306207.1 CDS Tmel_0961 NC_009616.1 992960 993160 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 992960..993160 Thermosipho melanesiensis BI429 5297911 YP_001306208.1 CDS rpsQ NC_009616.1 993166 993465 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 993166..993465 Thermosipho melanesiensis BI429 5297826 YP_001306209.1 CDS rplN NC_009616.1 993455 993823 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 993455..993823 Thermosipho melanesiensis BI429 5297827 YP_001306210.1 CDS rplX NC_009616.1 993837 994157 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 993837..994157 Thermosipho melanesiensis BI429 5297317 YP_001306211.1 CDS rplE NC_009616.1 994171 994719 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 994171..994719 Thermosipho melanesiensis BI429 5297318 YP_001306212.1 CDS rpsN NC_009616.1 994732 994917 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 994732..994917 Thermosipho melanesiensis BI429 5297821 YP_001306213.1 CDS rpsH NC_009616.1 994933 995337 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 994933..995337 Thermosipho melanesiensis BI429 5297822 YP_001306214.1 CDS rplF NC_009616.1 995351 995905 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 995351..995905 Thermosipho melanesiensis BI429 5297148 YP_001306215.1 CDS rplR NC_009616.1 995921 996289 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 995921..996289 Thermosipho melanesiensis BI429 5297149 YP_001306216.1 CDS rpsE NC_009616.1 996304 996834 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 996304..996834 Thermosipho melanesiensis BI429 5297321 YP_001306217.1 CDS rpmD NC_009616.1 996836 997021 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 996836..997021 Thermosipho melanesiensis BI429 5297322 YP_001306218.1 CDS rplO NC_009616.1 997036 997479 D late assembly protein; 50S ribosomal protein L15 997036..997479 Thermosipho melanesiensis BI429 5297062 YP_001306219.1 CDS secY NC_009616.1 997482 998768 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 997482..998768 Thermosipho melanesiensis BI429 5297063 YP_001306220.1 CDS adk NC_009616.1 998773 999417 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 998773..999417 Thermosipho melanesiensis BI429 5297726 YP_001306221.1 CDS Tmel_0975 NC_009616.1 999423 1000175 D TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; methionine aminopeptidase, type I 999423..1000175 Thermosipho melanesiensis BI429 5297727 YP_001306222.1 CDS infA NC_009616.1 1000181 1000405 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1000181..1000405 Thermosipho melanesiensis BI429 5296877 YP_001306223.1 CDS rpmJ NC_009616.1 1000424 1000540 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1000424..1000540 Thermosipho melanesiensis BI429 5296878 YP_001306224.1 CDS rpsM NC_009616.1 1000553 1000921 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1000553..1000921 Thermosipho melanesiensis BI429 5297055 YP_001306225.1 CDS Tmel_0979 NC_009616.1 1000934 1001323 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1000934..1001323 Thermosipho melanesiensis BI429 5297056 YP_001306226.1 CDS rpsD NC_009616.1 1001337 1001966 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1001337..1001966 Thermosipho melanesiensis BI429 5296545 YP_001306227.1 CDS Tmel_0981 NC_009616.1 1001973 1002959 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1001973..1002959 Thermosipho melanesiensis BI429 5296546 YP_001306228.1 CDS rplQ NC_009616.1 1002961 1003344 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1002961..1003344 Thermosipho melanesiensis BI429 5296613 YP_001306229.1 CDS Tmel_0983 NC_009616.1 1003385 1004692 D PFAM: trigger factor, C-terminal domain protein; trigger factor, N-terminal domain; trigger factor domain-containing protein 1003385..1004692 Thermosipho melanesiensis BI429 5296614 YP_001306230.1 CDS clpP NC_009616.1 1004676 1005284 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1004676..1005284 Thermosipho melanesiensis BI429 5297543 YP_001306231.1 CDS Tmel_0985 NC_009616.1 1005333 1006091 D PFAM: protein of unknown function DUF28; hypothetical protein 1005333..1006091 Thermosipho melanesiensis BI429 5297544 YP_001306232.1 CDS Tmel_0986 NC_009616.1 1006093 1006815 D hypothetical protein 1006093..1006815 Thermosipho melanesiensis BI429 5297286 YP_001306233.1 CDS Tmel_0987 NC_009616.1 1006796 1007608 D PFAM: MCP methyltransferase, CheR-type; protein-glutamate O-methyltransferase 1006796..1007608 Thermosipho melanesiensis BI429 5297287 YP_001306234.1 CDS Tmel_0988 NC_009616.1 1007618 1008163 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1007618..1008163 Thermosipho melanesiensis BI429 5296882 YP_001306235.1 CDS Tmel_0989 NC_009616.1 1008030 1008950 D TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; RluA family pseudouridine synthase 1008030..1008950 Thermosipho melanesiensis BI429 5296883 YP_001306236.1 CDS Tmel_0990 NC_009616.1 1009036 1010355 D TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; glutamine synthetase, type I 1009036..1010355 Thermosipho melanesiensis BI429 5296740 YP_001306237.1 CDS Tmel_0991 NC_009616.1 1010370 1011230 R TIGRFAM: cysteinyl-tRNA synthetase; PFAM: TM1410 hypothetical-related protein; cysteinyl-tRNA synthetase complement(1010370..1011230) Thermosipho melanesiensis BI429 5296741 YP_001306238.1 CDS Tmel_0992 NC_009616.1 1011227 1013497 R hypothetical protein complement(1011227..1013497) Thermosipho melanesiensis BI429 5296867 YP_001306239.1 CDS Tmel_0993 NC_009616.1 1013494 1014885 R hypothetical protein complement(1013494..1014885) Thermosipho melanesiensis BI429 5296868 YP_001306240.1 CDS Tmel_0994 NC_009616.1 1014887 1016302 R PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase complement(1014887..1016302) Thermosipho melanesiensis BI429 5297805 YP_001306241.1 CDS Tmel_0995 NC_009616.1 1016295 1016681 R hypothetical protein complement(1016295..1016681) Thermosipho melanesiensis BI429 5297806 YP_001306242.1 CDS Tmel_0996 NC_009616.1 1016686 1017543 R hypothetical protein complement(1016686..1017543) Thermosipho melanesiensis BI429 5296615 YP_001306243.1 CDS Tmel_0997 NC_009616.1 1017540 1018736 R hypothetical protein complement(1017540..1018736) Thermosipho melanesiensis BI429 5296616 YP_001306244.1 CDS Tmel_0998 NC_009616.1 1019023 1020426 D TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1019023..1020426 Thermosipho melanesiensis BI429 5296574 YP_001306245.1 CDS Tmel_0999 NC_009616.1 1020429 1020908 D hypothetical protein 1020429..1020908 Thermosipho melanesiensis BI429 5296575 YP_001306246.1 CDS Tmel_1000 NC_009616.1 1020905 1021618 D PFAM: peptidase M22, glycoprotease; peptidase M22, glycoprotease 1020905..1021618 Thermosipho melanesiensis BI429 5297018 YP_001306247.1 CDS Tmel_1001 NC_009616.1 1021611 1024070 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1021611..1024070 Thermosipho melanesiensis BI429 5297019 YP_001306248.1 CDS Tmel_1002 NC_009616.1 1024067 1025749 D PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1024067..1025749 Thermosipho melanesiensis BI429 5296495 YP_001306249.1 CDS Tmel_1003 NC_009616.1 1025743 1026261 R PFAM: AMMECR1 domain protein; AMMECR1 domain-containing protein complement(1025743..1026261) Thermosipho melanesiensis BI429 5296496 YP_001306250.1 CDS Tmel_1004 NC_009616.1 1026258 1026770 R hypothetical protein complement(1026258..1026770) Thermosipho melanesiensis BI429 5296888 YP_001306251.1 CDS Tmel_1005 NC_009616.1 1026767 1027342 R hypothetical protein complement(1026767..1027342) Thermosipho melanesiensis BI429 5296889 YP_001306252.1 CDS Tmel_1006 NC_009616.1 1027348 1028211 R PFAM: phosphoadenosine phosphosulfate reductase; PP-loop domain protein; PP-loop domain-containing protein complement(1027348..1028211) Thermosipho melanesiensis BI429 5297516 YP_001306253.1 CDS Tmel_1007 NC_009616.1 1028224 1029417 R PFAM: protein of unknown function DUF1063; hypothetical protein complement(1028224..1029417) Thermosipho melanesiensis BI429 5297517 YP_001306254.1 CDS Tmel_1008 NC_009616.1 1029488 1031047 D PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; OB-fold, tRNA/helicase-type nucleic acid binding protein 1029488..1031047 Thermosipho melanesiensis BI429 5297428 YP_001306255.1 CDS Tmel_1009 NC_009616.1 1031072 1032613 R PFAM: carbohydrate kinase, FGGY; carbohydrate kinase, FGGY complement(1031072..1032613) Thermosipho melanesiensis BI429 5297429 YP_001306256.1 CDS Tmel_1010 NC_009616.1 1032680 1033792 R TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein complement(1032680..1033792) Thermosipho melanesiensis BI429 5296491 YP_001306257.1 CDS Tmel_1011 NC_009616.1 1034056 1037022 R PFAM: glycoside hydrolase, family 38; glycosyl hydrolase 38 domain protein; Glycoside hydrolase, family 38, central region; glycoside hydrolase family protein complement(1034056..1037022) Thermosipho melanesiensis BI429 5296492 YP_001306258.1 CDS Tmel_1012 NC_009616.1 1037015 1038043 R PFAM: regulatory protein GntR, HTH; periplasmic binding protein/LacI transcriptional regulator; regulatory protein GntR complement(1037015..1038043) Thermosipho melanesiensis BI429 5297796 YP_001306259.1 CDS Tmel_1013 NC_009616.1 1038054 1038992 R PFAM: glycosidase, PH1107-related; glycosidase complement(1038054..1038992) Thermosipho melanesiensis BI429 5297797 YP_001306260.1 CDS Tmel_1014 NC_009616.1 1039006 1039827 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1039006..1039827) Thermosipho melanesiensis BI429 5297004 YP_001306261.1 CDS Tmel_1015 NC_009616.1 1039839 1040717 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1039839..1040717) Thermosipho melanesiensis BI429 5297005 YP_001306262.1 CDS Tmel_1016 NC_009616.1 1040769 1043411 R PFAM: coagulation factor 5/8 type domain protein; PKD domain containing protein; glycoside hydrolase, family 85; glycoside hydrolase family protein complement(1040769..1043411) Thermosipho melanesiensis BI429 5296580 YP_001306263.1 CDS Tmel_1017 NC_009616.1 1043423 1044676 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(1043423..1044676) Thermosipho melanesiensis BI429 5296581 YP_001306264.1 CDS Tmel_1018 NC_009616.1 1044942 1047527 D PFAM: MMPL domain protein; MMPL domain-containing protein 1044942..1047527 Thermosipho melanesiensis BI429 5296712 YP_001306265.1 CDS Tmel_1019 NC_009616.1 1047524 1048288 D hypothetical protein 1047524..1048288 Thermosipho melanesiensis BI429 5296713 YP_001306266.1 CDS Tmel_1020 NC_009616.1 1048305 1049507 D hypothetical protein 1048305..1049507 Thermosipho melanesiensis BI429 5296840 YP_001306267.1 CDS Tmel_1021 NC_009616.1 1049524 1050006 D PFAM: PHA accumulation regulator DNA-binding protein; PHA accumulation regulator DNA-binding protein 1049524..1050006 Thermosipho melanesiensis BI429 5296841 YP_001306268.1 CDS Tmel_1022 NC_009616.1 1050008 1050763 D PFAM: transferase hexapeptide repeat containing protein; hexapaptide repeat-containing transferase 1050008..1050763 Thermosipho melanesiensis BI429 5297875 YP_001306269.1 CDS Tmel_1023 NC_009616.1 1050748 1051248 R PFAM: Chromate transporter; chromate transporter complement(1050748..1051248) Thermosipho melanesiensis BI429 5297876 YP_001306270.1 CDS Tmel_1024 NC_009616.1 1051259 1053349 R TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DNA topoisomerase I complement(1051259..1053349) Thermosipho melanesiensis BI429 5296777 YP_001306271.1 CDS Tmel_1025 NC_009616.1 1053351 1054361 R TIGRFAM: metal dependent phophohydrolase; PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(1053351..1054361) Thermosipho melanesiensis BI429 5296778 YP_001306272.1 CDS Tmel_1026 NC_009616.1 1054358 1055452 R TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein; alanine racemase complement(1054358..1055452) Thermosipho melanesiensis BI429 5296899 YP_001306273.1 CDS rpmB NC_009616.1 1055778 1055990 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1055778..1055990) Thermosipho melanesiensis BI429 5296900 YP_001306274.1 CDS Tmel_1028 NC_009616.1 1056104 1058668 R PFAM: protein of unknown function DUF214; hypothetical protein complement(1056104..1058668) Thermosipho melanesiensis BI429 5296796 YP_001306275.1 CDS Tmel_1029 NC_009616.1 1058678 1059790 R TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma-70; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; RpoD family RNA polymerase sigma factor complement(1058678..1059790) Thermosipho melanesiensis BI429 5296797 YP_001306276.1 CDS Tmel_1030 NC_009616.1 1059798 1061390 R TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein; DNA primase complement(1059798..1061390) Thermosipho melanesiensis BI429 5297038 YP_001306277.1 CDS rpsI NC_009616.1 1061448 1061846 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(1061448..1061846) Thermosipho melanesiensis BI429 5297039 YP_001306278.1 CDS rplM NC_009616.1 1061862 1062353 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(1061862..1062353) Thermosipho melanesiensis BI429 5297699 YP_001306279.1 CDS Tmel_1033 NC_009616.1 1062328 1062861 R hypothetical protein complement(1062328..1062861) Thermosipho melanesiensis BI429 5297700 YP_001306280.1 CDS rpmA NC_009616.1 1062873 1063130 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1062873..1063130) Thermosipho melanesiensis BI429 5297021 YP_001306281.1 CDS Tmel_1035 NC_009616.1 1063120 1063431 R PFAM: protein of unknown function DUF464; hypothetical protein complement(1063120..1063431) Thermosipho melanesiensis BI429 5297022 YP_001306282.1 CDS rplU NC_009616.1 1063428 1063748 R PFAM: ribosomal protein L21; 50S ribosomal protein L21 complement(1063428..1063748) Thermosipho melanesiensis BI429 5297110 YP_001306283.1 CDS Tmel_1037 NC_009616.1 1063982 1065082 D PFAM: major facilitator superfamily MFS_1; major facilitator transporter 1063982..1065082 Thermosipho melanesiensis BI429 5297111 YP_001306284.1 CDS ruvC NC_009616.1 1065085 1065558 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1065085..1065558 Thermosipho melanesiensis BI429 5297112 YP_001306285.1 CDS polC NC_009616.1 1065570 1069658 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1065570..1069658 Thermosipho melanesiensis BI429 5297113 YP_001306286.1 CDS Tmel_1040 NC_009616.1 1069834 1070109 D PFAM: Stage V sporulation protein S; stage V sporulation protein S 1069834..1070109 Thermosipho melanesiensis BI429 5297253 YP_001306287.1 CDS Tmel_1041 NC_009616.1 1070117 1070350 D hypothetical protein 1070117..1070350 Thermosipho melanesiensis BI429 5297254 YP_001306288.1 CDS Tmel_1042 NC_009616.1 1070381 1071238 D PFAM: protein of unknown function DUF1385; hypothetical protein 1070381..1071238 Thermosipho melanesiensis BI429 5296497 YP_001306289.1 CDS Tmel_1043 NC_009616.1 1071247 1072395 R TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; diaminopimelate decarboxylase complement(1071247..1072395) Thermosipho melanesiensis BI429 5296498 YP_001306290.1 CDS Tmel_1044 NC_009616.1 1072392 1073486 R TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; amidohydrolase complement(1072392..1073486) Thermosipho melanesiensis BI429 5296690 YP_001306291.1 CDS pheS NC_009616.1 1073582 1074556 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1073582..1074556 Thermosipho melanesiensis BI429 5296691 YP_001306292.1 CDS Tmel_1046 NC_009616.1 1074558 1075472 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1074558..1075472 Thermosipho melanesiensis BI429 5297737 YP_001306293.1 CDS Tmel_1047 NC_009616.1 1075513 1076580 D PFAM: TGS domain protein; Protein of unknown function DUF933; hypothetical protein 1075513..1076580 Thermosipho melanesiensis BI429 5297738 YP_001306294.1 CDS Tmel_1048 NC_009616.1 1076592 1076828 D hypothetical protein 1076592..1076828 Thermosipho melanesiensis BI429 5297614 YP_001306295.1 CDS Tmel_1049 NC_009616.1 1076819 1078015 D PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1076819..1078015 Thermosipho melanesiensis BI429 5297615 YP_001306296.1 CDS Tmel_1050 NC_009616.1 1077990 1078784 D PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 1077990..1078784 Thermosipho melanesiensis BI429 5297479 YP_001306297.1 CDS Tmel_1051 NC_009616.1 1078781 1079521 D PFAM: zinc/iron permease; zinc/iron permease 1078781..1079521 Thermosipho melanesiensis BI429 5297480 YP_001306298.1 CDS Tmel_1052 NC_009616.1 1079533 1080612 D PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; oxidoreductase domain-containing protein 1079533..1080612 Thermosipho melanesiensis BI429 5297809 YP_001306299.1 CDS Tmel_1053 NC_009616.1 1080621 1081286 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; HAD family hydrolase 1080621..1081286 Thermosipho melanesiensis BI429 5297810 YP_001306300.1 CDS Tmel_1055 NC_009616.1 1082086 1083171 R PFAM: 2-nitropropane dioxygenase, NPD; 2-nitropropane dioxygenase complement(1082086..1083171) Thermosipho melanesiensis BI429 5297141 YP_001306301.1 CDS Tmel_1056 NC_009616.1 1083916 1085466 D PFAM: protein of unknown function DUF1703; hypothetical protein 1083916..1085466 Thermosipho melanesiensis BI429 5297565 YP_001306302.1 CDS Tmel_1057 NC_009616.1 1085683 1086243 R hypothetical protein complement(1085683..1086243) Thermosipho melanesiensis BI429 5296563 YP_001306303.1 CDS Tmel_1058 NC_009616.1 1086255 1086977 R hypothetical protein complement(1086255..1086977) Thermosipho melanesiensis BI429 5296564 YP_001306304.1 CDS Tmel_1059 NC_009616.1 1087090 1087425 R ECF subfamily RNA polymerase sigma-24 factor complement(1087090..1087425) Thermosipho melanesiensis BI429 5296665 YP_001306305.1 CDS Tmel_1060 NC_009616.1 1087469 1087657 R hypothetical protein complement(1087469..1087657) Thermosipho melanesiensis BI429 5296666 YP_001306306.1 CDS Tmel_1061 NC_009616.1 1087669 1087881 R hypothetical protein complement(1087669..1087881) Thermosipho melanesiensis BI429 5297743 YP_001306307.1 CDS Tmel_1062 NC_009616.1 1087907 1088092 R hypothetical protein complement(1087907..1088092) Thermosipho melanesiensis BI429 5297744 YP_001306308.1 CDS Tmel_1063 NC_009616.1 1088824 1090122 D PFAM: sugar transferase; sugar transferase 1088824..1090122 Thermosipho melanesiensis BI429 5297639 YP_001306309.1 CDS Tmel_1064 NC_009616.1 1090124 1091233 D PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1090124..1091233 Thermosipho melanesiensis BI429 5297640 YP_001306310.1 CDS Tmel_1065 NC_009616.1 1091247 1092410 D hypothetical protein 1091247..1092410 Thermosipho melanesiensis BI429 5297759 YP_001306311.1 CDS Tmel_1066 NC_009616.1 1092422 1093537 D hypothetical protein 1092422..1093537 Thermosipho melanesiensis BI429 5297760 YP_001306312.1 CDS Tmel_1067 NC_009616.1 1093621 1094796 D PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like; UDP-glucose 6-dehydrogenase 1093621..1094796 Thermosipho melanesiensis BI429 5297197 YP_001306313.1 CDS Tmel_1068 NC_009616.1 1094812 1095726 D PFAM: glycosyl transferase, family 2; glycosyl transferase family protein 1094812..1095726 Thermosipho melanesiensis BI429 5297198 YP_001306314.1 CDS Tmel_1069 NC_009616.1 1095750 1096640 D TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; glucose-1-phosphate thymidylyltransferase 1095750..1096640 Thermosipho melanesiensis BI429 5296762 YP_001306315.1 CDS Tmel_1070 NC_009616.1 1096657 1097229 D TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1096657..1097229 Thermosipho melanesiensis BI429 5296763 YP_001306316.1 CDS Tmel_1071 NC_009616.1 1097226 1098083 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 1097226..1098083 Thermosipho melanesiensis BI429 5297162 YP_001306317.1 CDS Tmel_1072 NC_009616.1 1098096 1099154 D TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; dTDP-glucose 4,6-dehydratase 1098096..1099154 Thermosipho melanesiensis BI429 5297163 YP_001306318.1 CDS Tmel_1073 NC_009616.1 1099164 1100414 D PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase 1099164..1100414 Thermosipho melanesiensis BI429 5297298 YP_001306319.1 CDS Tmel_1074 NC_009616.1 1100419 1101849 D PFAM: polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 1100419..1101849 Thermosipho melanesiensis BI429 5297299 YP_001306320.1 CDS Tmel_1075 NC_009616.1 1101849 1102352 D TIGRFAM: cytidyltransferase-related domain; glycerol-3-phosphate cytidylyltransferase; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; glycerol-3-phosphate cytidylyltransferase 1101849..1102352 Thermosipho melanesiensis BI429 5296804 YP_001306321.1 CDS Tmel_1076 NC_009616.1 1102757 1103341 D hypothetical protein 1102757..1103341 Thermosipho melanesiensis BI429 5296805 YP_001306322.1 CDS Tmel_1077 NC_009616.1 1103771 1103962 D hypothetical protein 1103771..1103962 Thermosipho melanesiensis BI429 5297325 YP_001306323.1 CDS Tmel_1078 NC_009616.1 1104048 1104260 D hypothetical protein 1104048..1104260 Thermosipho melanesiensis BI429 5297326 YP_001306324.1 CDS Tmel_1079 NC_009616.1 1104274 1104462 D hypothetical protein 1104274..1104462 Thermosipho melanesiensis BI429 5296920 YP_001306325.1 CDS Tmel_1080 NC_009616.1 1104588 1104920 D hypothetical protein 1104588..1104920 Thermosipho melanesiensis BI429 5296921 YP_001306326.1 CDS Tmel_1081 NC_009616.1 1105139 1106104 D TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; UDP-glucose 4-epimerase 1105139..1106104 Thermosipho melanesiensis BI429 5296981 YP_001306327.1 CDS Tmel_1082 NC_009616.1 1106198 1106374 D hypothetical protein 1106198..1106374 Thermosipho melanesiensis BI429 5296982 YP_001306328.1 CDS Tmel_1083 NC_009616.1 1106437 1107381 D PFAM: metallophosphoesterase; metallophosphoesterase 1106437..1107381 Thermosipho melanesiensis BI429 5296654 YP_001306329.1 CDS Tmel_1084 NC_009616.1 1107417 1107617 D hypothetical protein 1107417..1107617 Thermosipho melanesiensis BI429 5296655 YP_001306330.1 CDS Tmel_1085 NC_009616.1 1107598 1109823 D DNA repair ATPase-like protein 1107598..1109823 Thermosipho melanesiensis BI429 5296617 YP_001306331.1 CDS Tmel_1086 NC_009616.1 1109921 1110223 D hypothetical protein 1109921..1110223 Thermosipho melanesiensis BI429 5296618 YP_001306332.1 CDS Tmel_1087 NC_009616.1 1110306 1112156 D ATP-dependent OLD family endonuclease 1110306..1112156 Thermosipho melanesiensis BI429 5296971 YP_001306333.1 CDS Tmel_1088 NC_009616.1 1112303 1113343 D PFAM: AAA-4 family protein; putative transcriptional regulator 1112303..1113343 Thermosipho melanesiensis BI429 5296972 YP_001306334.1 CDS Tmel_1089 NC_009616.1 1113613 1114953 D hypothetical protein 1113613..1114953 Thermosipho melanesiensis BI429 5297157 YP_001306335.1 CDS Tmel_1090 NC_009616.1 1115021 1118725 D PFAM: KAP P-loop domain protein; KAP P-loop domain-containing protein 1115021..1118725 Thermosipho melanesiensis BI429 5297158 YP_001306336.1 CDS Tmel_1091 NC_009616.1 1119207 1119521 D hypothetical protein 1119207..1119521 Thermosipho melanesiensis BI429 5297851 YP_001306337.1 CDS Tmel_1092 NC_009616.1 1119791 1120021 D hypothetical protein 1119791..1120021 Thermosipho melanesiensis BI429 5297852 YP_001306338.1 CDS Tmel_1093 NC_009616.1 1121044 1122417 D PFAM: DUF234 DEXX-box ATPase; ATPase; ATPase 1121044..1122417 Thermosipho melanesiensis BI429 5296787 YP_001306339.1 CDS Tmel_1094 NC_009616.1 1122856 1123107 D hypothetical protein 1122856..1123107 Thermosipho melanesiensis BI429 5296788 YP_001306340.1 CDS Tmel_1095 NC_009616.1 1123216 1123860 R hypothetical protein complement(1123216..1123860) Thermosipho melanesiensis BI429 5297710 YP_001306341.1 CDS Tmel_1097 NC_009616.1 1124974 1125141 R hypothetical protein complement(1124974..1125141) Thermosipho melanesiensis BI429 5298268 YP_001306342.1 CDS Tmel_1098 NC_009616.1 1125191 1126018 D arylsulfatase regulator (Fe-S oxidoreductase)-like protein 1125191..1126018 Thermosipho melanesiensis BI429 5296728 YP_001306343.1 CDS Tmel_1099 NC_009616.1 1126113 1127399 D PFAM: peptidase S41; peptidase S41 1126113..1127399 Thermosipho melanesiensis BI429 5296729 YP_001306344.1 CDS Tmel_1100 NC_009616.1 1127420 1127632 D hypothetical protein 1127420..1127632 Thermosipho melanesiensis BI429 5297883 YP_001306345.1 CDS Tmel_1103 NC_009616.1 1129513 1130130 D PFAM: Domain of unknown function DUF1814; hypothetical protein 1129513..1130130 Thermosipho melanesiensis BI429 5298205 YP_001306346.1 CDS Tmel_1105 NC_009616.1 1131072 1132448 R SMART: AAA ATPase; AAA ATPase complement(1131072..1132448) Thermosipho melanesiensis BI429 5298206 YP_001306347.1 CDS Tmel_1106 NC_009616.1 1132884 1133210 D hypothetical protein 1132884..1133210 Thermosipho melanesiensis BI429 5296952 YP_001306348.1 CDS Tmel_1108 NC_009616.1 1133488 1136049 D hypothetical protein 1133488..1136049 Thermosipho melanesiensis BI429 5298115 YP_001306349.1 CDS Tmel_1109 NC_009616.1 1136283 1137179 D PFAM: protein of unknown function DUF1130; hypothetical protein 1136283..1137179 Thermosipho melanesiensis BI429 5296647 YP_001306350.1 CDS Tmel_1110 NC_009616.1 1137176 1138012 D hypothetical protein 1137176..1138012 Thermosipho melanesiensis BI429 5296949 YP_001306351.1 CDS Tmel_1111 NC_009616.1 1138473 1139387 D hypothetical protein 1138473..1139387 Thermosipho melanesiensis BI429 5296950 YP_001306352.1 CDS Tmel_1112 NC_009616.1 1139381 1140121 D PFAM: Methyltransferase type 11; Methyltransferase type 12; type 11 methyltransferase 1139381..1140121 Thermosipho melanesiensis BI429 5297341 YP_001306353.1 CDS Tmel_1113 NC_009616.1 1140137 1140994 D PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1140137..1140994 Thermosipho melanesiensis BI429 5297342 YP_001306354.1 CDS Tmel_1114 NC_009616.1 1141987 1142904 D hypothetical protein 1141987..1142904 Thermosipho melanesiensis BI429 5297133 YP_001306355.1 CDS Tmel_1115 NC_009616.1 1143023 1143175 D hypothetical protein 1143023..1143175 Thermosipho melanesiensis BI429 5297134 YP_001306356.1 CDS Tmel_1116 NC_009616.1 1143193 1143510 D hypothetical protein 1143193..1143510 Thermosipho melanesiensis BI429 5297447 YP_001306357.1 CDS Tmel_1117 NC_009616.1 1143973 1144137 D hypothetical protein 1143973..1144137 Thermosipho melanesiensis BI429 5297448 YP_001306358.1 CDS Tmel_1118 NC_009616.1 1144401 1144946 R hypothetical protein complement(1144401..1144946) Thermosipho melanesiensis BI429 5296842 YP_001306359.1 CDS Tmel_1119 NC_009616.1 1145082 1145348 D hypothetical protein 1145082..1145348 Thermosipho melanesiensis BI429 5296843 YP_001306360.1 CDS Tmel_1120 NC_009616.1 1146026 1148020 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(1146026..1148020) Thermosipho melanesiensis BI429 5297200 YP_001306361.1 CDS Tmel_1121 NC_009616.1 1148311 1149042 D PFAM: metallophosphoesterase; metallophosphoesterase 1148311..1149042 Thermosipho melanesiensis BI429 5297201 YP_001306362.1 CDS minC NC_009616.1 1149039 1149635 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1149039..1149635) Thermosipho melanesiensis BI429 5297551 YP_001306363.1 CDS Tmel_1123 NC_009616.1 1149744 1150577 D PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1149744..1150577 Thermosipho melanesiensis BI429 5297552 YP_001306364.1 CDS Tmel_1124 NC_009616.1 1150604 1150987 D TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; flagellar basal-body rod protein FlgB 1150604..1150987 Thermosipho melanesiensis BI429 5297605 YP_001306365.1 CDS Tmel_1125 NC_009616.1 1150999 1151412 D TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal-body rod protein FlgC 1150999..1151412 Thermosipho melanesiensis BI429 5297606 YP_001306366.1 CDS Tmel_1126 NC_009616.1 1151418 1151705 D TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex subunit FliE 1151418..1151705 Thermosipho melanesiensis BI429 5297170 YP_001306367.1 CDS Tmel_1127 NC_009616.1 1151803 1152231 R PFAM: heat shock protein Hsp20; heat shock protein Hsp20 complement(1151803..1152231) Thermosipho melanesiensis BI429 5297171 YP_001306368.1 CDS dnaK NC_009616.1 1152254 1154044 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1152254..1154044) Thermosipho melanesiensis BI429 5297048 YP_001306369.1 CDS Tmel_1129 NC_009616.1 1154198 1154524 R PFAM: protein of unknown function DUF74; hypothetical protein complement(1154198..1154524) Thermosipho melanesiensis BI429 5297049 YP_001306370.1 CDS Tmel_1130 NC_009616.1 1154538 1155740 R hypothetical protein complement(1154538..1155740) Thermosipho melanesiensis BI429 5297535 YP_001306371.1 CDS Tmel_1131 NC_009616.1 1155743 1156486 R hypothetical protein complement(1155743..1156486) Thermosipho melanesiensis BI429 5297536 YP_001306372.1 CDS Tmel_1132 NC_009616.1 1156483 1157259 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1156483..1157259) Thermosipho melanesiensis BI429 5297410 YP_001306373.1 CDS Tmel_1133 NC_009616.1 1157246 1157614 R PFAM: regulatory protein GntR, HTH; regulatory protein GntR complement(1157246..1157614) Thermosipho melanesiensis BI429 5297411 YP_001306374.1 CDS Tmel_1134 NC_009616.1 1157731 1158927 R TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase complement(1157731..1158927) Thermosipho melanesiensis BI429 5297677 YP_001306375.1 CDS Tmel_1135 NC_009616.1 1158947 1159591 R TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit B complement(1158947..1159591) Thermosipho melanesiensis BI429 5298464 YP_001306376.1 CDS Tmel_1136 NC_009616.1 1159588 1160241 R TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit A complement(1159588..1160241) Thermosipho melanesiensis BI429 5298465 YP_001306377.1 CDS Tmel_1137 NC_009616.1 1160409 1161719 R PFAM: Alkaline phosphatase; alkaline phosphatase complement(1160409..1161719) Thermosipho melanesiensis BI429 5298468 YP_001306378.1 CDS Tmel_1138 NC_009616.1 1161915 1163291 R TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutamate synthase (NADPH), homotetrameric complement(1161915..1163291) Thermosipho melanesiensis BI429 5298469 YP_001306379.1 CDS Tmel_1139 NC_009616.1 1163282 1164118 R PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; ferredoxin-NADP(+) reductase subunit alpha complement(1163282..1164118) Thermosipho melanesiensis BI429 5296829 YP_001306380.1 CDS Tmel_1140 NC_009616.1 1164132 1164956 R PFAM: PfkB domain protein; ribokinase-like domain-containing protein complement(1164132..1164956) Thermosipho melanesiensis BI429 5296830 YP_001306381.1 CDS Tmel_1141 NC_009616.1 1164934 1165860 R PFAM: ROK family protein; ROK family protein complement(1164934..1165860) Thermosipho melanesiensis BI429 5297424 YP_001306382.1 CDS Tmel_1142 NC_009616.1 1165857 1166618 R biotin synthetase-like protein complement(1165857..1166618) Thermosipho melanesiensis BI429 5297425 YP_001306383.1 CDS Tmel_1143 NC_009616.1 1166612 1167475 R PFAM: Radical SAM domain protein; radical SAM domain-containing protein complement(1166612..1167475) Thermosipho melanesiensis BI429 5297512 YP_001306384.1 CDS Tmel_1144 NC_009616.1 1167472 1168734 R PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(1167472..1168734) Thermosipho melanesiensis BI429 5297513 YP_001306385.1 CDS Tmel_1145 NC_009616.1 1168747 1170000 R PFAM: response regulator receiver; response regulator receiver protein complement(1168747..1170000) Thermosipho melanesiensis BI429 5297108 YP_001306386.1 CDS Tmel_1146 NC_009616.1 1170006 1170551 R hypothetical protein complement(1170006..1170551) Thermosipho melanesiensis BI429 5297109 YP_001306387.1 CDS Tmel_1147 NC_009616.1 1170544 1171110 R PFAM: response regulator receiver; response regulator receiver protein complement(1170544..1171110) Thermosipho melanesiensis BI429 5297101 YP_001306388.1 CDS Tmel_1148 NC_009616.1 1171169 1172302 R PFAM: ATP-binding region, ATPase domain protein domain protein; Hpt domain protein; CheA signal transduction histidine kinase complement(1171169..1172302) Thermosipho melanesiensis BI429 5296683 YP_001306389.1 CDS Tmel_1149 NC_009616.1 1172307 1172990 R hypothetical protein complement(1172307..1172990) Thermosipho melanesiensis BI429 5296684 YP_001306390.1 CDS Tmel_1150 NC_009616.1 1172995 1173993 R PFAM: MCP methyltransferase, CheR-type; MCP methyltransferase, CheR-type complement(1172995..1173993) Thermosipho melanesiensis BI429 5296858 YP_001306391.1 CDS Tmel_1151 NC_009616.1 1174059 1175009 D PFAM: DNA polymerase III, delta; DNA polymerase III subunit delta 1174059..1175009 Thermosipho melanesiensis BI429 5296859 YP_001306392.1 CDS Tmel_1152 NC_009616.1 1174993 1177071 D RND efflux transporter 1174993..1177071 Thermosipho melanesiensis BI429 5297310 YP_001306393.1 CDS Tmel_1153 NC_009616.1 1177079 1177606 D hypothetical protein 1177079..1177606 Thermosipho melanesiensis BI429 5297311 YP_001306394.1 CDS Tmel_1154 NC_009616.1 1177618 1178133 D hypothetical protein 1177618..1178133 Thermosipho melanesiensis BI429 5297601 YP_001306395.1 CDS Tmel_1155 NC_009616.1 1178138 1179421 D TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB; MiaB-like tRNA modifying protein YliG 1178138..1179421 Thermosipho melanesiensis BI429 5297602 YP_001306396.1 CDS Tmel_1156 NC_009616.1 1179428 1179949 D TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1179428..1179949 Thermosipho melanesiensis BI429 5297184 YP_001306397.1 CDS Tmel_1157 NC_009616.1 1179956 1180525 D TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase, HXTX; 2'-5' RNA ligase 1179956..1180525 Thermosipho melanesiensis BI429 5297185 YP_001306398.1 CDS recA NC_009616.1 1180518 1181567 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1180518..1181567 Thermosipho melanesiensis BI429 5297637 YP_001306399.1 CDS Tmel_1159 NC_009616.1 1181545 1181934 D PFAM: regulatory protein RecX; regulatory protein RecX 1181545..1181934 Thermosipho melanesiensis BI429 5297638 YP_001306400.1 CDS Tmel_1160 NC_009616.1 1181936 1183468 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1181936..1183468 Thermosipho melanesiensis BI429 5297020 YP_001306401.1 CDS Tmel_1161 NC_009616.1 1183499 1184602 R PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein complement(1183499..1184602) Thermosipho melanesiensis BI429 5296588 YP_001306402.1 CDS Tmel_1162 NC_009616.1 1184614 1184868 R TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(1184614..1184868) Thermosipho melanesiensis BI429 5296589 YP_001306403.1 CDS Tmel_1163 NC_009616.1 1185013 1186461 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1185013..1186461 Thermosipho melanesiensis BI429 5297125 YP_001306404.1 CDS Tmel_1164 NC_009616.1 1186502 1187056 D PFAM: regulatory protein, TetR; TetR family transcriptional regulator 1186502..1187056 Thermosipho melanesiensis BI429 5297126 YP_001306405.1 CDS rpmE NC_009616.1 1187130 1187339 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1187130..1187339 Thermosipho melanesiensis BI429 5297073 YP_001306406.1 CDS Tmel_1166 NC_009616.1 1187403 1187774 D PFAM: RNA binding S1 domain protein; RNA-binding S1 domain-containing protein 1187403..1187774 Thermosipho melanesiensis BI429 5297074 YP_001306407.1 CDS Tmel_1168 NC_009616.1 1188081 1189697 R PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) complement(1188081..1189697) Thermosipho melanesiensis BI429 5298116 YP_001306408.1 CDS Tmel_1169 NC_009616.1 1189694 1190176 R PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit complement(1189694..1190176) Thermosipho melanesiensis BI429 5297698 YP_001306409.1 CDS Tmel_1170 NC_009616.1 1190199 1192007 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; NADH dehydrogenase (quinone) complement(1190199..1192007) Thermosipho melanesiensis BI429 5297302 YP_001306410.1 CDS Tmel_1171 NC_009616.1 1192023 1192400 R ferredoxin-like protein complement(1192023..1192400) Thermosipho melanesiensis BI429 5297303 YP_001306411.1 CDS Tmel_1172 NC_009616.1 1192400 1192891 R PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; NADH dehydrogenase (ubiquinone), 24 kDa subunit complement(1192400..1192891) Thermosipho melanesiensis BI429 5296992 YP_001306412.1 CDS Tmel_1173 NC_009616.1 1193046 1193951 R TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase-like; glutamate formiminotransferase complement(1193046..1193951) Thermosipho melanesiensis BI429 5296993 YP_001306413.1 CDS Tmel_1174 NC_009616.1 1193948 1194712 R PFAM: inositol monophosphatase; inositol-phosphate phosphatase complement(1193948..1194712) Thermosipho melanesiensis BI429 5297257 YP_001306414.1 CDS Tmel_1175 NC_009616.1 1194705 1196306 R PFAM: penicillin-binding protein, transpeptidase; peptidoglycan glycosyltransferase complement(1194705..1196306) Thermosipho melanesiensis BI429 5297549 YP_001306415.1 CDS gltX NC_009616.1 1196296 1197684 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1196296..1197684) Thermosipho melanesiensis BI429 5297550 YP_001306416.1 CDS Tmel_1177 NC_009616.1 1197690 1198193 R hypothetical protein complement(1197690..1198193) Thermosipho melanesiensis BI429 5296940 YP_001306417.1 CDS Tmel_1178 NC_009616.1 1198190 1198840 R PFAM: initiation factor 2B related; initiation factor 2B-like protein complement(1198190..1198840) Thermosipho melanesiensis BI429 5296941 YP_001306418.1 CDS Tmel_1179 NC_009616.1 1198833 1199777 R PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein complement(1198833..1199777) Thermosipho melanesiensis BI429 5297616 YP_001306419.1 CDS Tmel_1180 NC_009616.1 1199774 1200205 R PFAM: GatB/Yqey domain protein; GatB/Yqey domain-containing protein complement(1199774..1200205) Thermosipho melanesiensis BI429 5297617 YP_001306420.1 CDS Tmel_1181 NC_009616.1 1200210 1201157 R PFAM: histone deacetylase superfamily; histone deacetylase superfamily protein complement(1200210..1201157) Thermosipho melanesiensis BI429 5297724 YP_001306421.1 CDS Tmel_1182 NC_009616.1 1201159 1201596 R TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; RpiB/LacA/LacB family sugar-phosphate isomerase complement(1201159..1201596) Thermosipho melanesiensis BI429 5297725 YP_001306422.1 CDS Tmel_1183 NC_009616.1 1201610 1201948 R TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist complement(1201610..1201948) Thermosipho melanesiensis BI429 5297772 YP_001306423.1 CDS Tmel_1184 NC_009616.1 1201960 1202559 R TIGRFAM: LexA repressor; PFAM: peptidase S24, S26A and S26B; LexA DNA-binding domain protein; SOS-response transcriptional repressor, LexA complement(1201960..1202559) Thermosipho melanesiensis BI429 5297773 YP_001306424.1 CDS Tmel_1185 NC_009616.1 1202556 1202924 R hypothetical protein complement(1202556..1202924) Thermosipho melanesiensis BI429 5297585 YP_001306425.1 CDS Tmel_1186 NC_009616.1 1202917 1205337 R TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; DNA gyrase subunit A complement(1202917..1205337) Thermosipho melanesiensis BI429 5297586 YP_001306426.1 CDS Tmel_1187 NC_009616.1 1205352 1207256 R TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: t-RNA-binding domain protein; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase, class Ia-like; methionyl-tRNA synthetase complement(1205352..1207256) Thermosipho melanesiensis BI429 5296561 YP_001306427.1 CDS Tmel_1188 NC_009616.1 1207476 1208975 D PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 1207476..1208975 Thermosipho melanesiensis BI429 5297776 YP_001306428.1 CDS Tmel_1189 NC_009616.1 1209022 1210029 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1209022..1210029 Thermosipho melanesiensis BI429 5297777 YP_001306429.1 CDS Tmel_1190 NC_009616.1 1210041 1210913 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1210041..1210913 Thermosipho melanesiensis BI429 5297835 YP_001306430.1 CDS Tmel_1191 NC_009616.1 1210918 1211880 D TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1210918..1211880 Thermosipho melanesiensis BI429 5297836 YP_001306431.1 CDS Tmel_1192 NC_009616.1 1211877 1212851 D TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1211877..1212851 Thermosipho melanesiensis BI429 5296534 YP_001306432.1 CDS pyrB NC_009616.1 1212868 1214436 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit complement(1212868..1214436) Thermosipho melanesiensis BI429 5296535 YP_001306433.1 CDS Tmel_1194 NC_009616.1 1214487 1215506 R TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(1214487..1215506) Thermosipho melanesiensis BI429 5297477 YP_001306434.1 CDS Tmel_1195 NC_009616.1 1215759 1216169 D PFAM: ferric-uptake regulator; ferric uptake regulator family protein 1215759..1216169 Thermosipho melanesiensis BI429 5297478 YP_001306435.1 CDS Tmel_1196 NC_009616.1 1216171 1216809 D PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; peroxiredoxin 1216171..1216809 Thermosipho melanesiensis BI429 5297695 YP_001306436.1 CDS Tmel_1197 NC_009616.1 1216843 1217001 D PFAM: Rubredoxin-type Fe(Cys)4 protein; rubredoxin-type Fe(Cys)4 protein 1216843..1217001 Thermosipho melanesiensis BI429 5297696 YP_001306437.1 CDS Tmel_1198 NC_009616.1 1217003 1218157 D PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; beta-lactamase domain-containing protein 1217003..1218157 Thermosipho melanesiensis BI429 5296603 YP_001306438.1 CDS Tmel_1199 NC_009616.1 1218173 1218682 D PFAM: Ferritin, Dps family protein; ferroxidase 1218173..1218682 Thermosipho melanesiensis BI429 5296604 YP_001306439.1 CDS Tmel_1200 NC_009616.1 1218682 1218867 D PFAM: Helix-turn-helix, type 11 domain protein; helix-turn-helix, type 11 domain-containing protein 1218682..1218867 Thermosipho melanesiensis BI429 5296839 YP_001306440.1 CDS Tmel_1201 NC_009616.1 1218870 1219250 D TIGRFAM: desulfoferrodoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; desulfoferrodoxin 1218870..1219250 Thermosipho melanesiensis BI429 5297644 YP_001306441.1 CDS Tmel_1202 NC_009616.1 1219504 1219749 D hypothetical protein 1219504..1219749 Thermosipho melanesiensis BI429 5297645 YP_001306442.1 CDS Tmel_1203 NC_009616.1 1219751 1220020 D hypothetical protein 1219751..1220020 Thermosipho melanesiensis BI429 5297599 YP_001306443.1 CDS Tmel_1204 NC_009616.1 1220038 1221699 R TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(1220038..1221699) Thermosipho melanesiensis BI429 5297600 YP_001306444.1 CDS Tmel_1205 NC_009616.1 1221809 1222171 D PFAM: transcriptional regulator PadR family protein; PadR-like family transcriptional regulator 1221809..1222171 Thermosipho melanesiensis BI429 5296910 YP_001306445.1 CDS Tmel_1206 NC_009616.1 1222171 1222734 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1222171..1222734 Thermosipho melanesiensis BI429 5296911 YP_001306446.1 CDS Tmel_1207 NC_009616.1 1222731 1224521 D PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; 5'-nucleotidase domain-containing protein 1222731..1224521 Thermosipho melanesiensis BI429 5296582 YP_001306447.1 CDS Tmel_1208 NC_009616.1 1225036 1225677 R PFAM: protein of unknown function DUF1121; hypothetical protein complement(1225036..1225677) Thermosipho melanesiensis BI429 5296583 YP_001306448.1 CDS Tmel_1209 NC_009616.1 1225689 1226318 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(1225689..1226318) Thermosipho melanesiensis BI429 5297524 YP_001306449.1 CDS Tmel_1210 NC_009616.1 1226611 1227093 D subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 1226611..1227093 Thermosipho melanesiensis BI429 5297525 YP_001306450.1 CDS Tmel_1211 NC_009616.1 1227090 1227347 D subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 1227090..1227347 Thermosipho melanesiensis BI429 5296960 YP_001306451.1 CDS Tmel_1212 NC_009616.1 1227344 1227664 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 1227344..1227664 Thermosipho melanesiensis BI429 5296961 YP_001306452.1 CDS Tmel_1213 NC_009616.1 1227661 1227900 D hypothetical protein 1227661..1227900 Thermosipho melanesiensis BI429 5297459 YP_001306453.1 CDS Tmel_1214 NC_009616.1 1227897 1228616 D subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 1227897..1228616 Thermosipho melanesiensis BI429 5297250 YP_001306454.1 CDS Tmel_1215 NC_009616.1 1228616 1228960 D PFAM: NADH-ubiquinone oxidoreductase, chain 4L; NADH-ubiquinone oxidoreductase subunit 4L 1228616..1228960 Thermosipho melanesiensis BI429 5297251 YP_001306455.1 CDS Tmel_1216 NC_009616.1 1228957 1230309 D PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH/ubiquinone/plastoquinone (complex I) 1228957..1230309 Thermosipho melanesiensis BI429 5297518 YP_001306456.1 CDS Tmel_1217 NC_009616.1 1230310 1232154 D PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH dehydrogenase subunit M 1230310..1232154 Thermosipho melanesiensis BI429 5297519 YP_001306457.1 CDS Tmel_1218 NC_009616.1 1232157 1233038 D PFAM: respiratory-chain NADH dehydrogenase, subunit 1; respiratory-chain NADH dehydrogenase subunit 1 1232157..1233038 Thermosipho melanesiensis BI429 5297422 YP_001306458.1 CDS Tmel_1219 NC_009616.1 1233050 1233592 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1233050..1233592 Thermosipho melanesiensis BI429 5297423 YP_001306459.1 CDS Tmel_1220 NC_009616.1 1233573 1234103 D PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit; NADH dehydrogenase (ubiquinone), 30 kDa subunit 1233573..1234103 Thermosipho melanesiensis BI429 5296673 YP_001306460.1 CDS Tmel_1221 NC_009616.1 1234096 1235199 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1234096..1235199 Thermosipho melanesiensis BI429 5296674 YP_001306461.1 CDS Tmel_1222 NC_009616.1 1235215 1237065 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 1235215..1237065 Thermosipho melanesiensis BI429 5297376 YP_001306462.1 CDS Tmel_1223 NC_009616.1 1237067 1237570 D hypothetical protein 1237067..1237570 Thermosipho melanesiensis BI429 5297377 YP_001306463.1 CDS Tmel_1224 NC_009616.1 1237579 1238184 R MobA-like protein complement(1237579..1238184) Thermosipho melanesiensis BI429 5297607 YP_001306464.1 CDS Tmel_1226 NC_009616.1 1238626 1240551 D PFAM: glycoside hydrolase, family 20; glycoside hydrolase family protein 1238626..1240551 Thermosipho melanesiensis BI429 5298069 YP_001306465.1 CDS Tmel_1227 NC_009616.1 1240548 1241291 D PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1240548..1241291 Thermosipho melanesiensis BI429 5297609 YP_001306466.1 CDS Tmel_1228 NC_009616.1 1241288 1241650 D PFAM: transcriptional regulator PadR family protein; PadR-like family transcriptional regulator 1241288..1241650 Thermosipho melanesiensis BI429 5296601 YP_001306467.1 CDS Tmel_1229 NC_009616.1 1241767 1243107 D PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1241767..1243107 Thermosipho melanesiensis BI429 5296602 YP_001306468.1 CDS Tmel_1230 NC_009616.1 1243344 1243910 D PFAM: transferase hexapeptide repeat containing protein; Serine O-acetyltransferase 1243344..1243910 Thermosipho melanesiensis BI429 5297182 YP_001306469.1 CDS Tmel_1231 NC_009616.1 1243923 1244780 D PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta 1243923..1244780 Thermosipho melanesiensis BI429 5297183 YP_001306470.1 CDS Tmel_1232 NC_009616.1 1244987 1245439 D TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase, catalytic subunit 1244987..1245439 Thermosipho melanesiensis BI429 5297849 YP_001306471.1 CDS Tmel_1233 NC_009616.1 1245453 1246139 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1245453..1246139 Thermosipho melanesiensis BI429 5297850 YP_001306472.1 CDS Tmel_1234 NC_009616.1 1246115 1246363 D TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; phosphoribosylformylglycinamidine synthase PurS 1246115..1246363 Thermosipho melanesiensis BI429 5296724 YP_001306473.1 CDS Tmel_1235 NC_009616.1 1246360 1246992 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1246360..1246992 Thermosipho melanesiensis BI429 5296725 YP_001306474.1 CDS Tmel_1236 NC_009616.1 1246989 1248761 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1246989..1248761 Thermosipho melanesiensis BI429 5296827 YP_001306475.1 CDS Tmel_1237 NC_009616.1 1248920 1250542 D hypothetical protein 1248920..1250542 Thermosipho melanesiensis BI429 5296828 YP_001306476.1 CDS Tmel_1238 NC_009616.1 1250585 1251337 D hypothetical protein 1250585..1251337 Thermosipho melanesiensis BI429 5296704 YP_001306477.1 CDS Tmel_1239 NC_009616.1 1251409 1252227 D PFAM: Indigoidine synthase A family protein; indigoidine synthase A family protein 1251409..1252227 Thermosipho melanesiensis BI429 5296705 YP_001306478.1 CDS Tmel_1240 NC_009616.1 1252326 1252880 D TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; phosphodiesterase 1252326..1252880 Thermosipho melanesiensis BI429 5296592 YP_001306479.1 CDS Tmel_1241 NC_009616.1 1252877 1253470 D PFAM: protein of unknown function UPF0029; hypothetical protein 1252877..1253470 Thermosipho melanesiensis BI429 5296916 YP_001306480.1 CDS Tmel_1242 NC_009616.1 1253474 1254664 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1253474..1254664 Thermosipho melanesiensis BI429 5296917 YP_001306481.1 CDS Tmel_1243 NC_009616.1 1254675 1255958 R TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; adenylosuccinate lyase complement(1254675..1255958) Thermosipho melanesiensis BI429 5296539 YP_001306482.1 CDS Tmel_1244 NC_009616.1 1256066 1256395 D PFAM: regulatory protein, MarR; regulatory protein, ArsR; regulatory protein ArsR 1256066..1256395 Thermosipho melanesiensis BI429 5296540 YP_001306483.1 CDS Tmel_1245 NC_009616.1 1256382 1257266 D TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; cation diffusion facilitator family transporter 1256382..1257266 Thermosipho melanesiensis BI429 5297131 YP_001306484.1 CDS Tmel_1246 NC_009616.1 1257708 1258166 R hypothetical protein complement(1257708..1258166) Thermosipho melanesiensis BI429 5298070 YP_001306485.1 CDS Tmel_1247 NC_009616.1 1258189 1258767 R hypothetical protein complement(1258189..1258767) Thermosipho melanesiensis BI429 5297437 YP_001306486.1 CDS Tmel_1248 NC_009616.1 1258924 1259766 D response regulator receiver/SARP domain-containing protein 1258924..1259766 Thermosipho melanesiensis BI429 5297438 YP_001306487.1 CDS Tmel_1251 NC_009616.1 1260537 1260869 R hypothetical protein complement(1260537..1260869) Thermosipho melanesiensis BI429 5297138 YP_001306488.1 CDS Tmel_1252 NC_009616.1 1260870 1261001 R hypothetical protein complement(1260870..1261001) Thermosipho melanesiensis BI429 5297367 YP_001306489.1 CDS Tmel_1255 NC_009616.1 1262626 1263912 R hypothetical protein complement(1262626..1263912) Thermosipho melanesiensis BI429 5297839 YP_001306490.1 CDS Tmel_1256 NC_009616.1 1263909 1265018 R PFAM: Secretin/TonB, short N-terminal domain; secretin/TonB, short N-terminal domain complement(1263909..1265018) Thermosipho melanesiensis BI429 5297723 YP_001306491.1 CDS Tmel_1257 NC_009616.1 1265015 1266418 R hypothetical protein complement(1265015..1266418) Thermosipho melanesiensis BI429 5297333 YP_001306492.1 CDS Tmel_1258 NC_009616.1 1266592 1266954 D PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; putative 6-pyruvoyl tetrahydropterin synthase 1266592..1266954 Thermosipho melanesiensis BI429 5297803 YP_001306493.1 CDS Tmel_1259 NC_009616.1 1266954 1268072 D PFAM: aminotransferase, class I and II; class I and II aminotransferase 1266954..1268072 Thermosipho melanesiensis BI429 5297804 YP_001306494.1 CDS Tmel_1260 NC_009616.1 1268508 1269989 R PFAM: cation transporter; cation transporter complement(1268508..1269989) Thermosipho melanesiensis BI429 5297260 YP_001306495.1 CDS Tmel_1261 NC_009616.1 1269991 1270650 R PFAM: TrkA-N domain protein; TrkA-C domain protein; TrkA domain-containing protein complement(1269991..1270650) Thermosipho melanesiensis BI429 5297261 YP_001306496.1 CDS Tmel_1262 NC_009616.1 1270647 1271072 R PFAM: TrkA-N domain protein; TrkA domain-containing protein complement(1270647..1271072) Thermosipho melanesiensis BI429 5297215 YP_001306497.1 CDS Tmel_1263 NC_009616.1 1271056 1271649 R PFAM: response regulator receiver; response regulator receiver protein complement(1271056..1271649) Thermosipho melanesiensis BI429 5297216 YP_001306498.1 CDS Tmel_1264 NC_009616.1 1271700 1272422 R PFAM: triosephosphate isomerase; Triose-phosphate isomerase complement(1271700..1272422) Thermosipho melanesiensis BI429 5297642 YP_001306499.1 CDS pgk NC_009616.1 1272443 1273651 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1272443..1273651) Thermosipho melanesiensis BI429 5297643 YP_001306500.1 CDS Tmel_1266 NC_009616.1 1273719 1274717 R TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase, type I complement(1273719..1274717) Thermosipho melanesiensis BI429 5297403 YP_001306501.1 CDS Tmel_1267 NC_009616.1 1274811 1275524 R hypothetical protein complement(1274811..1275524) Thermosipho melanesiensis BI429 5297404 YP_001306502.1 CDS Tmel_1268 NC_009616.1 1275537 1276856 R hypothetical protein complement(1275537..1276856) Thermosipho melanesiensis BI429 5297435 YP_001306503.1 CDS Tmel_1269 NC_009616.1 1276868 1278172 R TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase; flagellar protein export ATPase FliI complement(1276868..1278172) Thermosipho melanesiensis BI429 5297436 YP_001306504.1 CDS Tmel_1270 NC_009616.1 1278165 1278854 R hypothetical protein complement(1278165..1278854) Thermosipho melanesiensis BI429 5296543 YP_001306505.1 CDS Tmel_1271 NC_009616.1 1278894 1280114 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1278894..1280114) Thermosipho melanesiensis BI429 5296833 YP_001306506.1 CDS Tmel_1272 NC_009616.1 1280137 1281072 R TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase, class-II; fructose-1,6-bisphosphate aldolase, class II complement(1280137..1281072) Thermosipho melanesiensis BI429 5296834 YP_001306507.1 CDS Tmel_1273 NC_009616.1 1281476 1281955 D hypothetical protein 1281476..1281955 Thermosipho melanesiensis BI429 5297944 YP_001306508.1 CDS Tmel_1274 NC_009616.1 1281961 1283223 D PFAM: cell division protein FtsA; cell division protein FtsA 1281961..1283223 Thermosipho melanesiensis BI429 5296719 YP_001306509.1 CDS Tmel_1275 NC_009616.1 1283226 1284320 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1283226..1284320 Thermosipho melanesiensis BI429 5296593 YP_001306510.1 CDS Tmel_1276 NC_009616.1 1284313 1286004 D PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase; type II secretion system protein E 1284313..1286004 Thermosipho melanesiensis BI429 5296594 YP_001306511.1 CDS Tmel_1277 NC_009616.1 1285994 1287145 D hypothetical protein 1285994..1287145 Thermosipho melanesiensis BI429 5297618 YP_001306512.1 CDS frr NC_009616.1 1287197 1287754 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1287197..1287754 Thermosipho melanesiensis BI429 5297619 YP_001306513.1 CDS Tmel_1279 NC_009616.1 1287756 1288433 D TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase 1287756..1288433 Thermosipho melanesiensis BI429 5297306 YP_001306514.1 CDS Tmel_1280 NC_009616.1 1288430 1289242 D PFAM: phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase 1288430..1289242 Thermosipho melanesiensis BI429 5297307 YP_001306515.1 CDS alaS NC_009616.1 1289256 1291835 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1289256..1291835 Thermosipho melanesiensis BI429 5297172 YP_001306516.1 CDS Tmel_1282 NC_009616.1 1291838 1292851 D TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; rod shape-determining protein MreB 1291838..1292851 Thermosipho melanesiensis BI429 5297173 YP_001306517.1 CDS Tmel_1283 NC_009616.1 1292848 1293462 D hypothetical protein 1292848..1293462 Thermosipho melanesiensis BI429 5296879 YP_001306518.1 CDS Tmel_1284 NC_009616.1 1293464 1294057 D PFAM: GGDEF domain containing protein; diguanylate cyclase 1293464..1294057 Thermosipho melanesiensis BI429 5297778 YP_001306519.1 CDS Tmel_1285 NC_009616.1 1294044 1295318 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1294044..1295318 Thermosipho melanesiensis BI429 5297779 YP_001306520.1 CDS Tmel_1286 NC_009616.1 1295324 1297108 D PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; polysaccharide biosynthesis protein CapD 1295324..1297108 Thermosipho melanesiensis BI429 5297780 YP_001306521.1 CDS Tmel_1287 NC_009616.1 1297105 1297611 D hypothetical protein 1297105..1297611 Thermosipho melanesiensis BI429 5297781 YP_001306522.1 CDS Tmel_1288 NC_009616.1 1297621 1297908 D hypothetical protein 1297621..1297908 Thermosipho melanesiensis BI429 5297166 YP_001306523.1 CDS Tmel_1289 NC_009616.1 1297959 1300016 D TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; translation elongation factor G 1297959..1300016 Thermosipho melanesiensis BI429 5297167 YP_001306524.1 CDS Tmel_1290 NC_009616.1 1300105 1301052 D hypothetical protein 1300105..1301052 Thermosipho melanesiensis BI429 5297025 YP_001306525.1 CDS Tmel_1291 NC_009616.1 1301049 1303259 D hypothetical protein 1301049..1303259 Thermosipho melanesiensis BI429 5297026 YP_001306526.1 CDS Tmel_1292 NC_009616.1 1303234 1303899 D PFAM: flagellar hook capping protein; flagellar hook capping protein 1303234..1303899 Thermosipho melanesiensis BI429 5297832 YP_001306527.1 CDS Tmel_1293 NC_009616.1 1303905 1306022 D PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; hypothetical protein 1303905..1306022 Thermosipho melanesiensis BI429 5297833 YP_001306528.1 CDS Tmel_1294 NC_009616.1 1306031 1306252 D PFAM: flagellar FlbD family protein; flagellar FlbD family protein 1306031..1306252 Thermosipho melanesiensis BI429 5297593 YP_001306529.1 CDS Tmel_1295 NC_009616.1 1306252 1307040 D PFAM: MotA/TolQ/ExbB proton channel; MotA/TolQ/ExbB proton channel 1306252..1307040 Thermosipho melanesiensis BI429 5297594 YP_001306530.1 CDS Tmel_1296 NC_009616.1 1307040 1307906 D flagellar motor protein-like protein 1307040..1307906 Thermosipho melanesiensis BI429 5297252 YP_001306531.1 CDS Tmel_1297 NC_009616.1 1307919 1308440 D PFAM: flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 1307919..1308440 Thermosipho melanesiensis BI429 5296597 YP_001306532.1 CDS Tmel_1298 NC_009616.1 1308454 1309443 D PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; flagellar motor switch protein FliM 1308454..1309443 Thermosipho melanesiensis BI429 5296598 YP_001306533.1 CDS Tmel_1299 NC_009616.1 1309440 1310552 D TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; CheC, inhibitor of MCP methylation 1309440..1310552 Thermosipho melanesiensis BI429 5297069 YP_001306534.1 CDS Tmel_1300 NC_009616.1 1310688 1312184 R PFAM: sodium:neurotransmitter symporter; sodium:neurotransmitter symporter complement(1310688..1312184) Thermosipho melanesiensis BI429 5297070 YP_001306535.1 CDS Tmel_1301 NC_009616.1 1312319 1313305 R PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATPase complement(1312319..1313305) Thermosipho melanesiensis BI429 5296865 YP_001306536.1 CDS Tmel_1302 NC_009616.1 1313292 1313837 R PFAM: chromosome segregation and condensation protein ScpB; putative transcriptional regulator complement(1313292..1313837) Thermosipho melanesiensis BI429 5296866 YP_001306537.1 CDS Tmel_1303 NC_009616.1 1313830 1314489 R PFAM: chromosome segregation and condensation protein ScpA; chromosome segregation and condensation protein ScpA complement(1313830..1314489) Thermosipho melanesiensis BI429 5296671 YP_001306538.1 CDS Tmel_1304 NC_009616.1 1314489 1315091 R PFAM: CBS domain containing protein; amino acid-binding ACT domain protein; signal-transduction protein complement(1314489..1315091) Thermosipho melanesiensis BI429 5296672 YP_001306539.1 CDS Tmel_1305 NC_009616.1 1315107 1316051 R hypothetical protein complement(1315107..1316051) Thermosipho melanesiensis BI429 5297703 YP_001306540.1 CDS Tmel_1306 NC_009616.1 1316008 1317186 R TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase complement(1316008..1317186) Thermosipho melanesiensis BI429 5297704 YP_001306541.1 CDS panB NC_009616.1 1317188 1317982 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(1317188..1317982) Thermosipho melanesiensis BI429 5296856 YP_001306542.1 CDS Tmel_1308 NC_009616.1 1318030 1318770 R PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein complement(1318030..1318770) Thermosipho melanesiensis BI429 5296857 YP_001306543.1 CDS Tmel_1309 NC_009616.1 1318833 1319795 D PFAM: polysaccharide pyruvyl transferase; polysaccharide pyruvyl transferase 1318833..1319795 Thermosipho melanesiensis BI429 5297368 YP_001306544.1 CDS Tmel_1310 NC_009616.1 1319785 1320549 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1319785..1320549) Thermosipho melanesiensis BI429 5297678 YP_001306545.1 CDS Tmel_1311 NC_009616.1 1320533 1321066 R PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase complement(1320533..1321066) Thermosipho melanesiensis BI429 5297679 YP_001306546.1 CDS Tmel_1312 NC_009616.1 1321077 1321418 R PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; acid phosphatase/vanadium-dependent haloperoxidase related complement(1321077..1321418) Thermosipho melanesiensis BI429 5297327 YP_001306547.1 CDS Tmel_1313 NC_009616.1 1321427 1321834 R putative anti-sigma regulatory factor, serine/threonine protein kinase complement(1321427..1321834) Thermosipho melanesiensis BI429 5297328 YP_001306548.1 CDS Tmel_1314 NC_009616.1 1321834 1322625 R PFAM: protein of unknown function DUF208; hypothetical protein complement(1321834..1322625) Thermosipho melanesiensis BI429 5297449 YP_001306549.1 CDS Tmel_1315 NC_009616.1 1322625 1323077 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1322625..1323077) Thermosipho melanesiensis BI429 5297450 YP_001306550.1 CDS Tmel_1316 NC_009616.1 1323074 1325200 R TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region; (p)ppGpp synthetase I SpoT/RelA complement(1323074..1325200) Thermosipho melanesiensis BI429 5296933 YP_001306551.1 CDS Tmel_1317 NC_009616.1 1325318 1326637 D hypothetical protein 1325318..1326637 Thermosipho melanesiensis BI429 5296934 YP_001306552.1 CDS Tmel_1318 NC_009616.1 1326637 1328115 D PFAM: peptidase C1A, papain; peptidase C1A, papain 1326637..1328115 Thermosipho melanesiensis BI429 5297680 YP_001306553.1 CDS Tmel_1319 NC_009616.1 1328152 1330458 R PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase complement(1328152..1330458) Thermosipho melanesiensis BI429 5297681 YP_001306554.1 CDS Tmel_1320 NC_009616.1 1330458 1330901 R PFAM: ferredoxin; [2Fe-2S]-binding domain protein; 2Fe-2S iron-sulfur cluster binding domain-containing protein complement(1330458..1330901) Thermosipho melanesiensis BI429 5297245 YP_001306555.1 CDS Tmel_1321 NC_009616.1 1330901 1331659 R PFAM: molybdopterin dehydrogenase, FAD-binding; FAD-binding molybdopterin dehydrogenase complement(1330901..1331659) Thermosipho melanesiensis BI429 5297246 YP_001306556.1 CDS Tmel_1322 NC_009616.1 1331664 1332494 R PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein; FAD-binding molybdopterin dehydrogenase complement(1331664..1332494) Thermosipho melanesiensis BI429 5297736 YP_001306557.1 CDS Tmel_1323 NC_009616.1 1332487 1332942 R PFAM: ferredoxin; [2Fe-2S]-binding domain protein; 2Fe-2S iron-sulfur cluster binding domain-containing protein complement(1332487..1332942) Thermosipho melanesiensis BI429 5297362 YP_001306558.1 CDS Tmel_1324 NC_009616.1 1332939 1334147 R TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; threonine synthase complement(1332939..1334147) Thermosipho melanesiensis BI429 5297363 YP_001306559.1 CDS Tmel_1325 NC_009616.1 1334295 1334837 D TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1334295..1334837 Thermosipho melanesiensis BI429 5297067 YP_001306560.1 CDS Tmel_1326 NC_009616.1 1334834 1335238 D hypothetical protein 1334834..1335238 Thermosipho melanesiensis BI429 5297068 YP_001306561.1 CDS thrS NC_009616.1 1335251 1337161 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1335251..1337161 Thermosipho melanesiensis BI429 5296902 YP_001306562.1 CDS Tmel_1328 NC_009616.1 1337166 1337972 D PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1337166..1337972 Thermosipho melanesiensis BI429 5296903 YP_001306563.1 CDS Tmel_1329 NC_009616.1 1337999 1338409 D PFAM: protein of unknown function DUF107; hypothetical protein 1337999..1338409 Thermosipho melanesiensis BI429 5297693 YP_001306564.1 CDS Tmel_1330 NC_009616.1 1338409 1339323 D PFAM: band 7 protein; hypothetical protein 1338409..1339323 Thermosipho melanesiensis BI429 5297694 YP_001306565.1 CDS Tmel_1331 NC_009616.1 1339316 1339795 D hypothetical protein 1339316..1339795 Thermosipho melanesiensis BI429 5297186 YP_001306566.1 CDS Tmel_1332 NC_009616.1 1339810 1340934 D hypothetical protein 1339810..1340934 Thermosipho melanesiensis BI429 5297187 YP_001306567.1 CDS Tmel_1333 NC_009616.1 1341049 1342209 D PFAM: Orn/DAP/Arg decarboxylase 2; Orn/DAP/Arg decarboxylase 2 1341049..1342209 Thermosipho melanesiensis BI429 5297891 YP_001306568.1 CDS Tmel_1334 NC_009616.1 1342361 1343086 D TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; WecB/TagA/CpsF family glycosyl transferase 1342361..1343086 Thermosipho melanesiensis BI429 5297748 YP_001306569.1 CDS Tmel_1335 NC_009616.1 1343083 1343712 D TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; methyltransferase GidB 1343083..1343712 Thermosipho melanesiensis BI429 5297972 YP_001306570.1 CDS trmE NC_009616.1 1343725 1345050 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1343725..1345050 Thermosipho melanesiensis BI429 5297815 YP_001306571.1 CDS Tmel_1337 NC_009616.1 1345304 1345978 R PFAM: protein of unknown function DUF124; hypothetical protein complement(1345304..1345978) Thermosipho melanesiensis BI429 5297816 YP_001306572.1 CDS Tmel_1338 NC_009616.1 1346040 1346813 D hypothetical protein 1346040..1346813 Thermosipho melanesiensis BI429 5297620 YP_001306573.1 CDS Tmel_1339 NC_009616.1 1346808 1348112 R PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like; UDP-glucose 6-dehydrogenase complement(1346808..1348112) Thermosipho melanesiensis BI429 5297621 YP_001306574.1 CDS Tmel_1340 NC_009616.1 1348257 1348871 D PFAM: phosphoesterase, PA-phosphatase related; PA-phosphatase-like phosphoesterase 1348257..1348871 Thermosipho melanesiensis BI429 5298248 YP_001306575.1 CDS Tmel_1341 NC_009616.1 1348949 1350103 D PFAM: major facilitator superfamily MFS_1; major facilitator transporter 1348949..1350103 Thermosipho melanesiensis BI429 5298249 YP_001306576.1 CDS Tmel_1342 NC_009616.1 1350131 1351030 D PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9 prolyl oligopeptidase 1350131..1351030 Thermosipho melanesiensis BI429 5298332 YP_001306577.1 CDS Tmel_1343 NC_009616.1 1351023 1352012 D hypothetical protein 1351023..1352012 Thermosipho melanesiensis BI429 5298333 YP_001306578.1 CDS Tmel_1344 NC_009616.1 1352013 1353410 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(1352013..1353410) Thermosipho melanesiensis BI429 5297455 YP_001306579.1 CDS Tmel_1345 NC_009616.1 1353591 1354286 D PFAM: glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 1353591..1354286 Thermosipho melanesiensis BI429 5297456 YP_001306580.1 CDS Tmel_1346 NC_009616.1 1354295 1355470 R TIGRFAM: 8-amino-7-oxononanoate synthase; pyridoxal phosphate-dependent acyltransferase, putative; PFAM: glycine hydroxymethyltransferase; aminotransferase, class I and II; aminotransferase class-III; pyridoxal phosphate-dependent acyltransferase complement(1354295..1355470) Thermosipho melanesiensis BI429 5297577 YP_001306581.1 CDS Tmel_1347 NC_009616.1 1355482 1356513 R PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase complement(1355482..1356513) Thermosipho melanesiensis BI429 5297578 YP_001306582.1 CDS Tmel_1348 NC_009616.1 1356635 1357342 R hypothetical protein complement(1356635..1357342) Thermosipho melanesiensis BI429 5297958 YP_001306583.1 CDS Tmel_1349 NC_009616.1 1357699 1357866 R hypothetical protein complement(1357699..1357866) Thermosipho melanesiensis BI429 5298428 YP_001306584.1 CDS Tmel_1350 NC_009616.1 1357940 1358119 R hypothetical protein complement(1357940..1358119) Thermosipho melanesiensis BI429 5298429 YP_001306585.1 CDS Tmel_1351 NC_009616.1 1358161 1358613 R hypothetical protein complement(1358161..1358613) Thermosipho melanesiensis BI429 5297947 YP_001306586.1 CDS Tmel_1353 NC_009616.1 1359094 1360455 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; MATE efflux family protein 1359094..1360455 Thermosipho melanesiensis BI429 5297486 YP_001306587.1 CDS Tmel_1354 NC_009616.1 1360495 1361337 D hypothetical protein 1360495..1361337 Thermosipho melanesiensis BI429 5298432 YP_001306588.1 CDS Tmel_1355 NC_009616.1 1361445 1362251 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1361445..1362251) Thermosipho melanesiensis BI429 5298433 YP_001306589.1 CDS Tmel_1356 NC_009616.1 1362238 1362783 R hypothetical protein complement(1362238..1362783) Thermosipho melanesiensis BI429 5298455 YP_001306590.1 CDS Tmel_1357 NC_009616.1 1362770 1363132 R PFAM: regulatory protein GntR, HTH; regulatory protein GntR complement(1362770..1363132) Thermosipho melanesiensis BI429 5298456 YP_001306591.1 CDS Tmel_1358 NC_009616.1 1363137 1364156 R hypothetical protein complement(1363137..1364156) Thermosipho melanesiensis BI429 5296678 YP_001306592.1 CDS aspA NC_009616.1 1365054 1366418 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(1365054..1366418) Thermosipho melanesiensis BI429 5297487 YP_001306593.1 CDS Tmel_1361 NC_009616.1 1366423 1367613 R TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; small GTP-binding protein complement(1366423..1367613) Thermosipho melanesiensis BI429 5297817 YP_001306594.1 CDS Tmel_1362 NC_009616.1 1367754 1368380 D hypothetical protein 1367754..1368380 Thermosipho melanesiensis BI429 5297818 YP_001306595.1 CDS Tmel_1363 NC_009616.1 1368370 1369368 D PFAM: Polyprenyl synthetase; polyprenyl synthetase 1368370..1369368 Thermosipho melanesiensis BI429 5297978 YP_001306596.1 CDS Tmel_1364 NC_009616.1 1369370 1369915 D hypothetical protein 1369370..1369915 Thermosipho melanesiensis BI429 5297867 YP_001306597.1 CDS Tmel_1365 NC_009616.1 1369920 1370534 D TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; uridine kinase 1369920..1370534 Thermosipho melanesiensis BI429 5297868 YP_001306598.1 CDS Tmel_1366 NC_009616.1 1370550 1372055 D PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1370550..1372055 Thermosipho melanesiensis BI429 5298259 YP_001306599.1 CDS Tmel_1367 NC_009616.1 1372057 1372800 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1372057..1372800 Thermosipho melanesiensis BI429 5298260 YP_001306600.1 CDS Tmel_1368 NC_009616.1 1372781 1374130 D PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1372781..1374130 Thermosipho melanesiensis BI429 5298233 YP_001306601.1 CDS Tmel_1369 NC_009616.1 1374114 1374734 D PFAM: peptidase M50; peptidase M50 1374114..1374734 Thermosipho melanesiensis BI429 5298234 YP_001306602.1 CDS Tmel_1370 NC_009616.1 1374737 1374988 D hypothetical protein 1374737..1374988 Thermosipho melanesiensis BI429 5298426 YP_001306603.1 CDS Tmel_1371 NC_009616.1 1374963 1375220 D hypothetical protein 1374963..1375220 Thermosipho melanesiensis BI429 5298427 YP_001306604.1 CDS Tmel_1372 NC_009616.1 1375201 1375992 D TIGRFAM: glutamate racemase; PFAM: Asp/Glu racemase; glutamate racemase 1375201..1375992 Thermosipho melanesiensis BI429 5298374 YP_001306605.1 CDS Tmel_1373 NC_009616.1 1375946 1376782 D PFAM: uncharacterised P-loop ATPase protein UPF0042; hypothetical protein 1375946..1376782 Thermosipho melanesiensis BI429 5298375 YP_001306606.1 CDS Tmel_1374 NC_009616.1 1376782 1377714 D PFAM: protein of unknown function UPF0052 and CofD; hypothetical protein 1376782..1377714 Thermosipho melanesiensis BI429 5298312 YP_001306607.1 CDS Tmel_1375 NC_009616.1 1377719 1378630 D PFAM: protein of unknown function DUF199; hypothetical protein 1377719..1378630 Thermosipho melanesiensis BI429 5298313 YP_001306608.1 CDS nrdR NC_009616.1 1378635 1379090 D PFAM: ATP-cone domain protein; transcriptional regulator NrdR 1378635..1379090 Thermosipho melanesiensis BI429 5298315 YP_001306609.1 CDS greA NC_009616.1 1379107 1379577 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1379107..1379577 Thermosipho melanesiensis BI429 5298250 YP_001306610.1 CDS lysS NC_009616.1 1379590 1381098 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1379590..1381098 Thermosipho melanesiensis BI429 5298251 YP_001306611.1 CDS Tmel_1379 NC_009616.1 1381095 1382705 D hypothetical protein 1381095..1382705 Thermosipho melanesiensis BI429 5298091 YP_001306612.1 CDS Tmel_1380 NC_009616.1 1382790 1383023 D PFAM: RNA-binding S4 domain protein; RNA-binding S4 domain-containing protein 1382790..1383023 Thermosipho melanesiensis BI429 5298092 YP_001306613.1 CDS Tmel_1381 NC_009616.1 1383020 1383934 D GAF domain-containing protein 1383020..1383934 Thermosipho melanesiensis BI429 5298018 YP_001306614.1 CDS Tmel_1382 NC_009616.1 1383946 1385682 D PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein 1383946..1385682 Thermosipho melanesiensis BI429 5298019 YP_001306615.1 CDS Tmel_1383 NC_009616.1 1386244 1386684 D hypothetical protein 1386244..1386684 Thermosipho melanesiensis BI429 5297244 YP_001306616.1 CDS Tmel_1384 NC_009616.1 1386704 1387714 D TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1386704..1387714 Thermosipho melanesiensis BI429 5298147 YP_001306617.1 CDS Tmel_1385 NC_009616.1 1387707 1388714 D TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 1387707..1388714 Thermosipho melanesiensis BI429 5298261 YP_001306618.1 CDS Tmel_1386 NC_009616.1 1388719 1390455 D PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein 1388719..1390455 Thermosipho melanesiensis BI429 5298262 YP_001306619.1 CDS Tmel_1387 NC_009616.1 1390518 1391483 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1390518..1391483 Thermosipho melanesiensis BI429 5298046 YP_001306620.1 CDS Tmel_1388 NC_009616.1 1391497 1393125 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1391497..1393125 Thermosipho melanesiensis BI429 5298047 YP_001306621.1 CDS Tmel_1389 NC_009616.1 1393428 1393895 R HAD superfamily hydrolase-like protein complement(1393428..1393895) Thermosipho melanesiensis BI429 5297557 YP_001306622.1 CDS Tmel_1390 NC_009616.1 1393908 1394411 R hypothetical protein complement(1393908..1394411) Thermosipho melanesiensis BI429 5297991 YP_001306623.1 CDS Tmel_1391 NC_009616.1 1394411 1394965 R hypothetical protein complement(1394411..1394965) Thermosipho melanesiensis BI429 5297992 YP_001306624.1 CDS Tmel_1392 NC_009616.1 1394995 1396047 R PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein complement(1394995..1396047) Thermosipho melanesiensis BI429 5298451 YP_001306625.1 CDS rho NC_009616.1 1396049 1397320 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(1396049..1397320) Thermosipho melanesiensis BI429 5298452 YP_001306626.1 CDS upp NC_009616.1 1397332 1397958 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1397332..1397958) Thermosipho melanesiensis BI429 5298370 YP_001306627.1 CDS Tmel_1395 NC_009616.1 1397948 1399024 R TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; peptide chain release factor 1 complement(1397948..1399024) Thermosipho melanesiensis BI429 5298371 YP_001306628.1 CDS Tmel_1396 NC_009616.1 1399006 1400073 R TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; twitching motility protein complement(1399006..1400073) Thermosipho melanesiensis BI429 5298339 YP_001306629.1 CDS Tmel_1397 NC_009616.1 1400075 1401457 R TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; DNA polymerase III subunits gamma and tau complement(1400075..1401457) Thermosipho melanesiensis BI429 5298340 YP_001306630.1 CDS miaA NC_009616.1 1401460 1402365 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1401460..1402365) Thermosipho melanesiensis BI429 5298325 YP_001306631.1 CDS Tmel_1399 NC_009616.1 1402369 1402992 R hypothetical protein complement(1402369..1402992) Thermosipho melanesiensis BI429 5298326 YP_001306632.1 CDS Tmel_1400 NC_009616.1 1402989 1403720 R hypothetical protein complement(1402989..1403720) Thermosipho melanesiensis BI429 5298077 YP_001306633.1 CDS Tmel_1401 NC_009616.1 1403698 1404492 R PFAM: Patatin; patatin complement(1403698..1404492) Thermosipho melanesiensis BI429 5298078 YP_001306634.1 CDS Tmel_1402 NC_009616.1 1404489 1405340 R TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2; apurinic endonuclease Apn1 complement(1404489..1405340) Thermosipho melanesiensis BI429 5298024 YP_001306635.1 CDS Tmel_1403 NC_009616.1 1405333 1405668 R PFAM: protein of unknown function DUF1622; hypothetical protein complement(1405333..1405668) Thermosipho melanesiensis BI429 5298085 YP_001306636.1 CDS Tmel_1404 NC_009616.1 1405673 1407397 R NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1405673..1407397) Thermosipho melanesiensis BI429 5298086 YP_001306637.1 CDS Tmel_1405 NC_009616.1 1407487 1408113 D hypothetical protein 1407487..1408113 Thermosipho melanesiensis BI429 5298376 YP_001306638.1 CDS Tmel_1406 NC_009616.1 1408101 1408703 D subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 1408101..1408703 Thermosipho melanesiensis BI429 5298377 YP_001306639.1 CDS Tmel_1407 NC_009616.1 1408713 1410017 D hypothetical protein 1408713..1410017 Thermosipho melanesiensis BI429 5298398 YP_001306640.1 CDS Tmel_1408 NC_009616.1 1410014 1410883 D PFAM: prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 1410014..1410883 Thermosipho melanesiensis BI429 5298399 YP_001306641.1 CDS Tmel_1409 NC_009616.1 1410880 1412088 D catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; cofactor-independent phosphoglycerate mutase 1410880..1412088 Thermosipho melanesiensis BI429 5298026 YP_001306642.1 CDS Tmel_1410 NC_009616.1 1412090 1413304 D PFAM: ComEC/Rec2-related protein; ComEC/Rec2-like protein 1412090..1413304 Thermosipho melanesiensis BI429 5298027 YP_001306643.1 CDS Tmel_1411 NC_009616.1 1413217 1413669 R PFAM: ferric-uptake regulator; ferric uptake regulator family protein complement(1413217..1413669) Thermosipho melanesiensis BI429 5298191 YP_001306644.1 CDS nusA NC_009616.1 1413685 1414719 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(1413685..1414719) Thermosipho melanesiensis BI429 5298192 YP_001306645.1 CDS Tmel_1413 NC_009616.1 1414732 1415175 R PFAM: protein of unknown function DUF150; hypothetical protein complement(1414732..1415175) Thermosipho melanesiensis BI429 5298184 YP_001306646.1 CDS Tmel_1414 NC_009616.1 1415419 1415688 D PFAM: protein of unknown function DUF861, cupin_3; hypothetical protein 1415419..1415688 Thermosipho melanesiensis BI429 5297979 YP_001306647.1 CDS Tmel_1415 NC_009616.1 1415711 1416334 D PFAM: Formiminotransferase-cyclodeaminase; formiminotransferase-cyclodeaminase 1415711..1416334 Thermosipho melanesiensis BI429 5298164 YP_001306648.1 CDS tgt NC_009616.1 1416318 1417421 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1416318..1417421 Thermosipho melanesiensis BI429 5297502 YP_001306649.1 CDS Tmel_1417 NC_009616.1 1417414 1418193 D hypothetical protein 1417414..1418193 Thermosipho melanesiensis BI429 5297503 YP_001306650.1 CDS Tmel_1418 NC_009616.1 1418194 1418724 D PFAM: phosphoribosyltransferase; Uracil phosphoribosyltransferase 1418194..1418724 Thermosipho melanesiensis BI429 5298059 YP_001306651.1 CDS glmM NC_009616.1 1418721 1420007 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1418721..1420007 Thermosipho melanesiensis BI429 5298060 YP_001306652.1 CDS Tmel_1420 NC_009616.1 1420012 1420317 D PFAM: protein of unknown function DUF59; hypothetical protein 1420012..1420317 Thermosipho melanesiensis BI429 5298033 YP_001306653.1 CDS Tmel_1421 NC_009616.1 1420314 1421099 D TIGRFAM: modification methylase, HemK family; HemK family modification methylase 1420314..1421099 Thermosipho melanesiensis BI429 5298034 YP_001306654.1 CDS rplI NC_009616.1 1421105 1421560 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1421105..1421560 Thermosipho melanesiensis BI429 5297370 YP_001306655.1 CDS Tmel_1423 NC_009616.1 1421557 1422396 D PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein 1421557..1422396 Thermosipho melanesiensis BI429 5297371 YP_001306656.1 CDS Tmel_1424 NC_009616.1 1422408 1423583 D PFAM: metallophosphoesterase; metallophosphoesterase 1422408..1423583 Thermosipho melanesiensis BI429 5296549 YP_001306657.1 CDS Tmel_1425 NC_009616.1 1423580 1426159 D PFAM: CBS domain containing protein; phosphoesterase, RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase, DHHA1; CBS domain-containing protein 1423580..1426159 Thermosipho melanesiensis BI429 5296550 YP_001306658.1 CDS Tmel_1426 NC_009616.1 1426156 1427304 D hypothetical protein 1426156..1427304 Thermosipho melanesiensis BI429 5296768 YP_001306659.1 CDS Tmel_1427 NC_009616.1 1427293 1428210 R hypothetical protein complement(1427293..1428210) Thermosipho melanesiensis BI429 5297057 YP_001306660.1 CDS Tmel_1428 NC_009616.1 1428207 1428884 R hypothetical protein complement(1428207..1428884) Thermosipho melanesiensis BI429 5297058 YP_001306661.1 CDS Tmel_1429 NC_009616.1 1428872 1429315 R hypothetical protein complement(1428872..1429315) Thermosipho melanesiensis BI429 5297208 YP_001306662.1 CDS Tmel_1430 NC_009616.1 1429312 1429614 R hypothetical protein complement(1429312..1429614) Thermosipho melanesiensis BI429 5297209 YP_001306663.1 CDS Tmel_1431 NC_009616.1 1429618 1430298 R TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; RNA polymerase sigma-28 subunit FliA/WhiG complement(1429618..1430298) Thermosipho melanesiensis BI429 5297292 YP_001306664.1 CDS Tmel_1432 NC_009616.1 1430295 1430777 R catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD complement(1430295..1430777) Thermosipho melanesiensis BI429 5297293 YP_001306665.1 CDS Tmel_1433 NC_009616.1 1430777 1431394 R PFAM: CheC domain protein; CheC, inhibitor of MCP methylation complement(1430777..1431394) Thermosipho melanesiensis BI429 5297213 YP_001306666.1 CDS Tmel_1434 NC_009616.1 1431405 1432067 R PFAM: type IV pilus assembly PilZ; type IV pilus assembly PilZ complement(1431405..1432067) Thermosipho melanesiensis BI429 5297214 YP_001306667.1 CDS Tmel_1435 NC_009616.1 1432082 1432615 R hypothetical protein complement(1432082..1432615) Thermosipho melanesiensis BI429 5296576 YP_001306668.1 CDS Tmel_1436 NC_009616.1 1432616 1433446 R PFAM: Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase complement(1432616..1433446) Thermosipho melanesiensis BI429 5296577 YP_001306669.1 CDS flhF NC_009616.1 1433430 1434551 R positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF complement(1433430..1434551) Thermosipho melanesiensis BI429 5296744 YP_001306670.1 CDS Tmel_1438 NC_009616.1 1434548 1436590 R TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; flagellar biosynthesis protein FlhA complement(1434548..1436590) Thermosipho melanesiensis BI429 5296745 YP_001306671.1 CDS Tmel_1439 NC_009616.1 1437133 1437531 R hypothetical protein complement(1437133..1437531) Thermosipho melanesiensis BI429 5296936 YP_001306672.1 CDS Tmel_1440 NC_009616.1 1437536 1437817 R hypothetical protein complement(1437536..1437817) Thermosipho melanesiensis BI429 5296792 YP_001306673.1 CDS Tmel_1441 NC_009616.1 1437807 1438001 R hypothetical protein complement(1437807..1438001) Thermosipho melanesiensis BI429 5296793 YP_001306674.1 CDS Tmel_1442 NC_009616.1 1438003 1438332 R hypothetical protein complement(1438003..1438332) Thermosipho melanesiensis BI429 5297247 YP_001306675.1 CDS Tmel_1443 NC_009616.1 1438307 1438549 R hypothetical protein complement(1438307..1438549) Thermosipho melanesiensis BI429 5297248 YP_001306676.1 CDS Tmel_1444 NC_009616.1 1438554 1439042 R hypothetical protein complement(1438554..1439042) Thermosipho melanesiensis BI429 5296605 YP_001306677.1 CDS Tmel_1445 NC_009616.1 1439303 1439656 R hypothetical protein complement(1439303..1439656) Thermosipho melanesiensis BI429 5296606 YP_001306678.1 CDS Tmel_1446 NC_009616.1 1439689 1442958 R PFAM: Fibronectin, type III domain protein; fibronectin, type III domain-containing protein complement(1439689..1442958) Thermosipho melanesiensis BI429 5297782 YP_001306679.1 CDS Tmel_1447 NC_009616.1 1443179 1444492 R hypothetical protein complement(1443179..1444492) Thermosipho melanesiensis BI429 5297783 YP_001306680.1 CDS Tmel_1448 NC_009616.1 1444595 1444939 R hypothetical protein complement(1444595..1444939) Thermosipho melanesiensis BI429 5296510 YP_001306681.1 CDS Tmel_1449 NC_009616.1 1444959 1448321 R TIGRFAM: phage tail tape measure protein, TP901 family; TP901 family phage tail tape measure protein complement(1444959..1448321) Thermosipho melanesiensis BI429 5296511 YP_001306682.1 CDS Tmel_1450 NC_009616.1 1448327 1448821 R hypothetical protein complement(1448327..1448821) Thermosipho melanesiensis BI429 5297560 YP_001306683.1 CDS Tmel_1451 NC_009616.1 1448805 1449170 R hypothetical protein complement(1448805..1449170) Thermosipho melanesiensis BI429 5297561 YP_001306684.1 CDS Tmel_1452 NC_009616.1 1449182 1450144 R hypothetical protein complement(1449182..1450144) Thermosipho melanesiensis BI429 5296935 YP_001306685.1 CDS Tmel_1453 NC_009616.1 1450159 1450518 R hypothetical protein complement(1450159..1450518) Thermosipho melanesiensis BI429 5297653 YP_001306686.1 CDS Tmel_1454 NC_009616.1 1450511 1450981 R hypothetical protein complement(1450511..1450981) Thermosipho melanesiensis BI429 5297654 YP_001306687.1 CDS Tmel_1455 NC_009616.1 1450978 1451463 R hypothetical protein complement(1450978..1451463) Thermosipho melanesiensis BI429 5297688 YP_001306688.1 CDS Tmel_1456 NC_009616.1 1451477 1451671 R hypothetical protein complement(1451477..1451671) Thermosipho melanesiensis BI429 5297689 YP_001306689.1 CDS Tmel_1457 NC_009616.1 1451726 1452814 R hypothetical protein complement(1451726..1452814) Thermosipho melanesiensis BI429 5296781 YP_001306690.1 CDS Tmel_1458 NC_009616.1 1452831 1453544 R hypothetical protein complement(1452831..1453544) Thermosipho melanesiensis BI429 5296782 YP_001306691.1 CDS Tmel_1459 NC_009616.1 1453561 1453827 R hypothetical protein complement(1453561..1453827) Thermosipho melanesiensis BI429 5296648 YP_001306692.1 CDS Tmel_1460 NC_009616.1 1453832 1454557 R hypothetical protein complement(1453832..1454557) Thermosipho melanesiensis BI429 5296649 YP_001306693.1 CDS Tmel_1461 NC_009616.1 1454619 1455860 R hypothetical protein complement(1454619..1455860) Thermosipho melanesiensis BI429 5296625 YP_001306694.1 CDS Tmel_1462 NC_009616.1 1455871 1457136 R PFAM: protein of unknown function DUF264; hypothetical protein complement(1455871..1457136) Thermosipho melanesiensis BI429 5296626 YP_001306695.1 CDS Tmel_1463 NC_009616.1 1457117 1457659 R hypothetical protein complement(1457117..1457659) Thermosipho melanesiensis BI429 5296621 YP_001306696.1 CDS Tmel_1464 NC_009616.1 1458338 1458511 R hypothetical protein complement(1458338..1458511) Thermosipho melanesiensis BI429 5296622 YP_001306697.1 CDS Tmel_1465 NC_009616.1 1458815 1459381 D PFAM: protein of unknown function DUF88; hypothetical protein 1458815..1459381 Thermosipho melanesiensis BI429 5297434 YP_001306698.1 CDS Tmel_1466 NC_009616.1 1459560 1459754 R hypothetical protein complement(1459560..1459754) Thermosipho melanesiensis BI429 5297787 YP_001306699.1 CDS Tmel_1467 NC_009616.1 1460292 1460759 R ECF subfamily RNA polymerase sigma-24 factor complement(1460292..1460759) Thermosipho melanesiensis BI429 5297788 YP_001306700.1 CDS Tmel_1468 NC_009616.1 1461153 1461329 R hypothetical protein complement(1461153..1461329) Thermosipho melanesiensis BI429 5297279 YP_001306701.1 CDS Tmel_1469 NC_009616.1 1461329 1462081 R hypothetical protein complement(1461329..1462081) Thermosipho melanesiensis BI429 5297280 YP_001306702.1 CDS Tmel_1470 NC_009616.1 1462430 1462996 R hypothetical protein complement(1462430..1462996) Thermosipho melanesiensis BI429 5296595 YP_001306703.1 CDS Tmel_1471 NC_009616.1 1462989 1463819 R PFAM: regulatory protein, Crp; CRP/FNR family transcriptional regulator complement(1462989..1463819) Thermosipho melanesiensis BI429 5296596 YP_001306704.1 CDS recT NC_009616.1 1463883 1464785 R PFAM: RecT protein; recombination and repair protein RecT complement(1463883..1464785) Thermosipho melanesiensis BI429 5296508 YP_001306705.1 CDS Tmel_1473 NC_009616.1 1464797 1465717 R Phage-like protein endonuclease-like protein complement(1464797..1465717) Thermosipho melanesiensis BI429 5296509 YP_001306706.1 CDS Tmel_1474 NC_009616.1 1465714 1465995 R hypothetical protein complement(1465714..1465995) Thermosipho melanesiensis BI429 5297753 YP_001306707.1 CDS Tmel_1475 NC_009616.1 1466266 1466478 R hypothetical protein complement(1466266..1466478) Thermosipho melanesiensis BI429 5297754 YP_001306708.1 CDS Tmel_1476 NC_009616.1 1466559 1467053 D hypothetical protein 1466559..1467053 Thermosipho melanesiensis BI429 5297798 YP_001306709.1 CDS Tmel_1477 NC_009616.1 1467101 1467355 R hypothetical protein complement(1467101..1467355) Thermosipho melanesiensis BI429 5297799 YP_001306710.1 CDS Tmel_1478 NC_009616.1 1467379 1467597 R PFAM: helix-turn-helix domain protein; XRE family transcriptional regulator complement(1467379..1467597) Thermosipho melanesiensis BI429 5297786 YP_001306711.1 CDS Tmel_1479 NC_009616.1 1467855 1468475 D PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; putative prophage repressor 1467855..1468475 Thermosipho melanesiensis BI429 5296572 YP_001306712.1 CDS Tmel_1480 NC_009616.1 1468486 1469253 D PFAM: DNA methylase N-4/N-6 domain protein; DNA methylase N-4/N-6 domain-containing protein 1468486..1469253 Thermosipho melanesiensis BI429 5296573 YP_001306713.1 CDS Tmel_1481 NC_009616.1 1469306 1469983 D Type II site-specific deoxyribonuclease 1469306..1469983 Thermosipho melanesiensis BI429 5296637 YP_001306714.1 CDS Tmel_1482 NC_009616.1 1470057 1470902 D hypothetical protein 1470057..1470902 Thermosipho melanesiensis BI429 5296638 YP_001306715.1 CDS Tmel_1483 NC_009616.1 1470964 1471674 D hypothetical protein 1470964..1471674 Thermosipho melanesiensis BI429 5297583 YP_001306716.1 CDS Tmel_1484 NC_009616.1 1471677 1472192 D hypothetical protein 1471677..1472192 Thermosipho melanesiensis BI429 5297584 YP_001306717.1 CDS Tmel_1485 NC_009616.1 1472204 1472605 D hypothetical protein 1472204..1472605 Thermosipho melanesiensis BI429 5296999 YP_001306718.1 CDS Tmel_1486 NC_009616.1 1472710 1474167 D PFAM: Resolvase, N-terminal domain; Recombinase; resolvase domain-containing protein 1472710..1474167 Thermosipho melanesiensis BI429 5297000 YP_001306719.1 CDS Tmel_1487 NC_009616.1 1474581 1475312 R PFAM: protein of unknown function DUF81; hypothetical protein complement(1474581..1475312) Thermosipho melanesiensis BI429 5297558 YP_001306720.1 CDS Tmel_1490 NC_009616.1 1476399 1477283 D PFAM: PSP1 domain protein; PSP1 domain-containing protein 1476399..1477283 Thermosipho melanesiensis BI429 5297930 YP_001306721.1 CDS Tmel_1491 NC_009616.1 1477270 1477410 D hypothetical protein 1477270..1477410 Thermosipho melanesiensis BI429 5297931 YP_001306722.1 CDS Tmel_1492 NC_009616.1 1477415 1477891 D PFAM: protein of unknown function UPF0079; hypothetical protein 1477415..1477891 Thermosipho melanesiensis BI429 5296751 YP_001306723.1 CDS Tmel_1493 NC_009616.1 1477872 1480265 D TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; ATP-dependent protease La 1477872..1480265 Thermosipho melanesiensis BI429 5296644 YP_001306724.1 CDS engB NC_009616.1 1480240 1480815 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1480240..1480815 Thermosipho melanesiensis BI429 5296645 YP_001306725.1 CDS argS NC_009616.1 1480812 1482443 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1480812..1482443 Thermosipho melanesiensis BI429 5297603 YP_001306726.1 CDS Tmel_1496 NC_009616.1 1482455 1483852 D PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; histidine kinase 1482455..1483852 Thermosipho melanesiensis BI429 5297604 YP_001306727.1 CDS Tmel_1497 NC_009616.1 1483853 1484710 D PFAM: metal-dependent phosphohydrolase, HD sub domain; Metal-dependent hydrolase HDOD; metal dependent phosphohydrolase 1483853..1484710 Thermosipho melanesiensis BI429 5297142 YP_001306728.1 CDS Tmel_1498 NC_009616.1 1484700 1485077 D PFAM: ribosome-binding factor A; ribosome-binding factor A 1484700..1485077 Thermosipho melanesiensis BI429 5297143 YP_001306729.1 CDS Tmel_1499 NC_009616.1 1485108 1485449 D PFAM: flagellar protein FlaG protein; flagellar protein FlaG protein 1485108..1485449 Thermosipho melanesiensis BI429 5297401 YP_001306730.1 CDS Tmel_1500 NC_009616.1 1485461 1487236 D PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook-associated 2 domain-containing protein 1485461..1487236 Thermosipho melanesiensis BI429 5297402 YP_001306731.1 CDS Tmel_1501 NC_009616.1 1487262 1488311 R PFAM: von Willebrand factor, type A; von Willebrand factor, type A complement(1487262..1488311) Thermosipho melanesiensis BI429 5296931 YP_001306732.1 CDS Tmel_1502 NC_009616.1 1488327 1488815 R hypothetical protein complement(1488327..1488815) Thermosipho melanesiensis BI429 5296932 YP_001306733.1 CDS Tmel_1503 NC_009616.1 1489007 1490029 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1489007..1490029 Thermosipho melanesiensis BI429 5296501 YP_001306734.1 CDS Tmel_1504 NC_009616.1 1490038 1490499 D PFAM: PASTA domain containing protein; PASTA domain-containing protein 1490038..1490499 Thermosipho melanesiensis BI429 5296502 YP_001306735.1 CDS Tmel_1505 NC_009616.1 1490496 1491362 D TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; ribosome small subunit-dependent GTPase A 1490496..1491362 Thermosipho melanesiensis BI429 5297089 YP_001306736.1 CDS Tmel_1506 NC_009616.1 1491362 1493026 D PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; radical SAM domain-containing protein 1491362..1493026 Thermosipho melanesiensis BI429 5297323 YP_001306737.1 CDS Tmel_1507 NC_009616.1 1493050 1494342 D PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; hypothetical protein 1493050..1494342 Thermosipho melanesiensis BI429 5297324 YP_001306738.1 CDS Tmel_1508 NC_009616.1 1494335 1494724 D TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; cytidine deaminase 1494335..1494724 Thermosipho melanesiensis BI429 5296663 YP_001306739.1 CDS Tmel_1509 NC_009616.1 1494721 1496244 D PFAM: SMC domain protein; SMC domain-containing protein 1494721..1496244 Thermosipho melanesiensis BI429 5296664 YP_001306740.1 CDS Tmel_1510 NC_009616.1 1496249 1496761 D hypothetical protein 1496249..1496761 Thermosipho melanesiensis BI429 5296746 YP_001306741.1 CDS Tmel_1511 NC_009616.1 1496741 1498729 R TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like; NAD-dependent DNA ligase complement(1496741..1498729) Thermosipho melanesiensis BI429 5296747 YP_001306742.1 CDS Tmel_1512 NC_009616.1 1498827 1499045 D hypothetical protein 1498827..1499045 Thermosipho melanesiensis BI429 5296680 YP_001306743.1 CDS Tmel_1513 NC_009616.1 1499049 1501163 R TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; ribonuclease R complement(1499049..1501163) Thermosipho melanesiensis BI429 5296681 YP_001306744.1 CDS Tmel_1514 NC_009616.1 1501168 1502418 R PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; NusB/RsmB/TIM44 complement(1501168..1502418) Thermosipho melanesiensis BI429 5296869 YP_001306745.1 CDS Tmel_1515 NC_009616.1 1502415 1503107 R PFAM: peptidase, membrane zinc metallopeptidase, putative; peptidase, membrane zinc metallopeptidase complement(1502415..1503107) Thermosipho melanesiensis BI429 5296870 YP_001306746.1 CDS Tmel_1516 NC_009616.1 1503114 1503770 R PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator complement(1503114..1503770) Thermosipho melanesiensis BI429 5296988 YP_001306747.1 CDS Tmel_1517 NC_009616.1 1503751 1504467 R TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; RNA methyltransferase complement(1503751..1504467) Thermosipho melanesiensis BI429 5296989 YP_001306748.1 CDS Tmel_1518 NC_009616.1 1504464 1505219 R TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; MazG family protein complement(1504464..1505219) Thermosipho melanesiensis BI429 5296696 YP_001306749.1 CDS Tmel_1519 NC_009616.1 1505183 1506178 R PFAM: protein of unknown function UPF0118; hypothetical protein complement(1505183..1506178) Thermosipho melanesiensis BI429 5297399 YP_001306750.1 CDS Tmel_1520 NC_009616.1 1506168 1507382 R hypothetical protein complement(1506168..1507382) Thermosipho melanesiensis BI429 5297400 YP_001306751.1 CDS Tmel_1521 NC_009616.1 1507462 1508643 D hypothetical protein 1507462..1508643 Thermosipho melanesiensis BI429 5296979 YP_001306752.1 CDS Tmel_1522 NC_009616.1 1508694 1510703 R RND efflux transporter complement(1508694..1510703) Thermosipho melanesiensis BI429 5296980 YP_001306753.1 CDS Tmel_1523 NC_009616.1 1510700 1511134 R hypothetical protein complement(1510700..1511134) Thermosipho melanesiensis BI429 5296816 YP_001306754.1 CDS Tmel_1524 NC_009616.1 1511124 1513595 R PFAM: DNA polymerase III, alpha subunit; DNA-directed DNA polymerase complement(1511124..1513595) Thermosipho melanesiensis BI429 5296817 YP_001306755.1 CDS Tmel_1525 NC_009616.1 1513592 1514236 R PFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase complement(1513592..1514236) Thermosipho melanesiensis BI429 5296754 YP_001306756.1 CDS Tmel_1526 NC_009616.1 1514294 1515091 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1514294..1515091 Thermosipho melanesiensis BI429 5296755 YP_001306757.1 CDS Tmel_1527 NC_009616.1 1515095 1516075 D PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; phosphoesterase domain-containing protein 1515095..1516075 Thermosipho melanesiensis BI429 5296818 YP_001306758.1 CDS Tmel_1528 NC_009616.1 1516099 1520118 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase 1516099..1520118 Thermosipho melanesiensis BI429 5296819 YP_001306759.1 CDS Tmel_1529 NC_009616.1 1520105 1520983 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1520105..1520983 Thermosipho melanesiensis BI429 5296994 YP_001306760.1 CDS Tmel_1530 NC_009616.1 1520996 1522336 D catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 1 1520996..1522336 Thermosipho melanesiensis BI429 5297819 YP_001306761.1 CDS Tmel_1531 NC_009616.1 1522341 1522766 D PFAM: regulatory protein, MarR; transcriptional regulator TrmB; transcriptional regulator TrmB 1522341..1522766 Thermosipho melanesiensis BI429 5297820 YP_001306762.1 CDS Tmel_1532 NC_009616.1 1522769 1524142 D PFAM: PEGA domain protein; PEGA domain-containing protein 1522769..1524142 Thermosipho melanesiensis BI429 5296528 YP_001306763.1 CDS Tmel_1533 NC_009616.1 1524143 1525441 D hypothetical protein 1524143..1525441 Thermosipho melanesiensis BI429 5296529 YP_001306764.1 CDS Tmel_1534 NC_009616.1 1525453 1526823 D PFAM: protein of unknown function DUF342; hypothetical protein 1525453..1526823 Thermosipho melanesiensis BI429 5297901 YP_001306765.1 CDS Tmel_1535 NC_009616.1 1526820 1527608 D PFAM: mannose-6-phosphate isomerase, type I; mannose-6-phosphate isomerase, type I 1526820..1527608 Thermosipho melanesiensis BI429 5297902 YP_001306766.1 CDS Tmel_1536 NC_009616.1 1527574 1528458 R PFAM: protein of unknown function DUF89; hypothetical protein complement(1527574..1528458) Thermosipho melanesiensis BI429 5296810 YP_001306767.1 CDS Tmel_1537 NC_009616.1 1528460 1528714 R PFAM: phosphopantetheine-binding; phosphopantetheine-binding complement(1528460..1528714) Thermosipho melanesiensis BI429 5297857 YP_001306768.1 CDS ruvB NC_009616.1 1528913 1529854 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1528913..1529854 Thermosipho melanesiensis BI429 5297858 YP_001306769.1 CDS Tmel_1539 NC_009616.1 1529844 1530530 D PFAM: alanine racemase domain protein; alanine racemase domain-containing protein 1529844..1530530 Thermosipho melanesiensis BI429 5296852 YP_001306770.1 CDS Tmel_1540 NC_009616.1 1530535 1530825 D PFAM: protein of unknown function YGGT; hypothetical protein 1530535..1530825 Thermosipho melanesiensis BI429 5296853 YP_001306771.1 CDS pnk NC_009616.1 1530822 1531577 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1530822..1531577 Thermosipho melanesiensis BI429 5297193 YP_001306772.1 CDS Tmel_1542 NC_009616.1 1531593 1532294 D PFAM: PhoU family protein; phosphate uptake regulator PhoU 1531593..1532294 Thermosipho melanesiensis BI429 5297194 YP_001306773.1 CDS Tmel_1543 NC_009616.1 1532291 1535581 D PFAM: permease YjgP/YjgQ family protein; permease YjgP/YjgQ family protein 1532291..1535581 Thermosipho melanesiensis BI429 5297489 YP_001306774.1 CDS Tmel_1544 NC_009616.1 1535597 1536904 D TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; protein of unknown function Met10; (Uracil-5)-methyltransferase; RNA methyltransferase 1535597..1536904 Thermosipho melanesiensis BI429 5297393 YP_001306775.1 CDS Tmel_1545 NC_009616.1 1536940 1537539 D PFAM: MGS domain protein; IMP cyclohydrolase 1536940..1537539 Thermosipho melanesiensis BI429 5297394 YP_001306776.1 CDS Tmel_1546 NC_009616.1 1537549 1538148 D hypothetical protein 1537549..1538148 Thermosipho melanesiensis BI429 5296875 YP_001306777.1 CDS Tmel_1547 NC_009616.1 1538132 1538401 D flagellar protein FhlB-like protein 1538132..1538401 Thermosipho melanesiensis BI429 5296876 YP_001306778.1 CDS Tmel_1548 NC_009616.1 1538403 1539305 D hypothetical protein 1538403..1539305 Thermosipho melanesiensis BI429 5296737 YP_001306779.1 CDS prfB NC_009616.1 1539324 1540433 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 1539324..1540433 Thermosipho melanesiensis BI429 5296738 YP_001306780.1 CDS Tmel_1550 NC_009616.1 1540444 1541247 D TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; septum site-determining protein MinD 1540444..1541247 Thermosipho melanesiensis BI429 5296849 YP_001306781.1 CDS Tmel_1551 NC_009616.1 1541253 1541519 D hypothetical protein 1541253..1541519 Thermosipho melanesiensis BI429 5297624 YP_001306782.1 CDS Tmel_1552 NC_009616.1 1541540 1542133 D hypothetical protein 1541540..1542133 Thermosipho melanesiensis BI429 5297625 YP_001306783.1 CDS Tmel_1553 NC_009616.1 1542145 1542369 D hypothetical protein 1542145..1542369 Thermosipho melanesiensis BI429 5296611 YP_001306784.1 CDS Tmel_1554 NC_009616.1 1542366 1543148 D hypothetical protein 1542366..1543148 Thermosipho melanesiensis BI429 5296612 YP_001306785.1 CDS Tmel_1555 NC_009616.1 1543150 1544037 D TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase; signal recognition particle-docking protein FtsY 1543150..1544037 Thermosipho melanesiensis BI429 5296639 YP_001306786.1 CDS Tmel_1556 NC_009616.1 1544039 1544707 D hypothetical protein 1544039..1544707 Thermosipho melanesiensis BI429 5296640 YP_001306787.1 CDS Tmel_1557 NC_009616.1 1544713 1546266 D PFAM: Peptidoglycan-binding LysM; peptidase M23B; 3D domain protein; peptidoglycan-binding LysM 1544713..1546266 Thermosipho melanesiensis BI429 5296894 YP_001306788.1 CDS Tmel_1558 NC_009616.1 1546269 1546715 D TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; BadM/Rrf2 family transcriptional regulator 1546269..1546715 Thermosipho melanesiensis BI429 5297080 YP_001306789.1 CDS Tmel_1559 NC_009616.1 1546769 1547788 D PFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1546769..1547788 Thermosipho melanesiensis BI429 5297081 YP_001306790.1 CDS Tmel_1560 NC_009616.1 1547766 1548278 D TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 1547766..1548278 Thermosipho melanesiensis BI429 5296692 YP_001306791.1 CDS Tmel_1561 NC_009616.1 1548275 1549438 D TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; cell envelope-related transcriptional attenuator 1548275..1549438 Thermosipho melanesiensis BI429 5296693 YP_001306792.1 CDS Tmel_1562 NC_009616.1 1549419 1550099 R PFAM: Endonuclease V; deoxyribonuclease V complement(1549419..1550099) Thermosipho melanesiensis BI429 5297015 YP_001306793.1 CDS Tmel_1563 NC_009616.1 1550101 1550808 R hypothetical protein complement(1550101..1550808) Thermosipho melanesiensis BI429 5297016 YP_001306794.1 CDS Tmel_1565 NC_009616.1 1551518 1552420 R TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; putative radical SAM protein complement(1551518..1552420) Thermosipho melanesiensis BI429 5297553 YP_001306795.1 CDS Tmel_1566 NC_009616.1 1552417 1553652 R PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase complement(1552417..1553652) Thermosipho melanesiensis BI429 5297934 YP_001306796.1 CDS Tmel_1567 NC_009616.1 1553649 1553987 R TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; iojap-like protein complement(1553649..1553987) Thermosipho melanesiensis BI429 5297935 YP_001306797.1 CDS Tmel_1568 NC_009616.1 1553993 1555291 R TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; FolC bifunctional protein complement(1553993..1555291) Thermosipho melanesiensis BI429 5297651 YP_001306798.1 CDS Tmel_1569 NC_009616.1 1555301 1557901 R TIGRFAM: valyl-tRNA synthetase; valyl-tRNA synthetase complement(1555301..1557901) Thermosipho melanesiensis BI429 5297652 YP_001306799.1 CDS Tmel_1570 NC_009616.1 1557894 1558310 R putative diguanylate cyclase complement(1557894..1558310) Thermosipho melanesiensis BI429 5296590 YP_001306800.1 CDS Tmel_1571 NC_009616.1 1558428 1559744 D TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; RnfABCDGE type electron transport complex subunit C 1558428..1559744 Thermosipho melanesiensis BI429 5296591 YP_001306801.1 CDS Tmel_1572 NC_009616.1 1559744 1560700 D TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; RnfABCDGE type electron transport complex subunit D 1559744..1560700 Thermosipho melanesiensis BI429 5296641 YP_001306802.1 CDS Tmel_1573 NC_009616.1 1560697 1561374 D TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; RnfABCDGE type electron transport complex subunit G 1560697..1561374 Thermosipho melanesiensis BI429 5296769 YP_001306803.1 CDS Tmel_1574 NC_009616.1 1561364 1561978 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1561364..1561978 Thermosipho melanesiensis BI429 5296770 YP_001306804.1 CDS Tmel_1575 NC_009616.1 1561975 1562550 D TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; RnfABCDGE type electron transport complex subunit A 1561975..1562550 Thermosipho melanesiensis BI429 5297482 YP_001306805.1 CDS Tmel_1576 NC_009616.1 1562719 1563987 D PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter 1562719..1563987 Thermosipho melanesiensis BI429 5296670 YP_001306806.1 CDS Tmel_1577 NC_009616.1 1563999 1564934 D TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; CaCA family Na(+)/Ca(+) antiporter 1563999..1564934 Thermosipho melanesiensis BI429 5297191 YP_001306807.1 CDS Tmel_1578 NC_009616.1 1564947 1566398 D TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase; inosine-5'-monophosphate dehydrogenase 1564947..1566398 Thermosipho melanesiensis BI429 5297192 YP_001306808.1 CDS Tmel_1579 NC_009616.1 1566654 1568351 D PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; methyl-accepting chemotaxis sensory transducer 1566654..1568351 Thermosipho melanesiensis BI429 5297413 YP_001306809.1 CDS Tmel_1580 NC_009616.1 1568430 1569857 D PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; alpha amylase catalytic subunit 1568430..1569857 Thermosipho melanesiensis BI429 5297507 YP_001306810.1 CDS Tmel_1581 NC_009616.1 1569872 1570570 D PFAM: Methyltransferase type 11; Methyltransferase type 12; type 11 methyltransferase 1569872..1570570 Thermosipho melanesiensis BI429 5297508 YP_001306811.1 CDS Tmel_1582 NC_009616.1 1570640 1571374 D catalyzes the formation of L-aspartate to iminoaspartate in NAD(+) biosynthesis; L-aspartate dehydrogenase 1570640..1571374 Thermosipho melanesiensis BI429 5297226 YP_001306812.1 CDS Tmel_1583 NC_009616.1 1571379 1572290 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1571379..1572290 Thermosipho melanesiensis BI429 5297227 YP_001306813.1 CDS Tmel_1584 NC_009616.1 1572292 1573104 D TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; nicotinate-nucleotide pyrophosphorylase 1572292..1573104 Thermosipho melanesiensis BI429 5296861 YP_001306814.1 CDS Tmel_1585 NC_009616.1 1573288 1574511 D PFAM: Beta-ketoacyl synthase-like; beta-ketoacyl synthase-like protein 1573288..1574511 Thermosipho melanesiensis BI429 5296862 YP_001306815.1 CDS Tmel_1586 NC_009616.1 1574514 1574921 D PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ 1574514..1574921 Thermosipho melanesiensis BI429 5297548 YP_001306816.1 CDS Tmel_1587 NC_009616.1 1574926 1575855 D PFAM: 2-nitropropane dioxygenase, NPD; 2-nitropropane dioxygenase 1574926..1575855 Thermosipho melanesiensis BI429 5296958 YP_001306817.1 CDS Tmel_1588 NC_009616.1 1575855 1576358 D PFAM: BioY protein; BioY protein 1575855..1576358 Thermosipho melanesiensis BI429 5296959 YP_001306818.1 CDS Tmel_1589 NC_009616.1 1576355 1577245 D PFAM: Acyl transferase; Acyl transferase 1576355..1577245 Thermosipho melanesiensis BI429 5296845 YP_001306819.1 CDS Tmel_1590 NC_009616.1 1577513 1578289 D in Methanocaldococcus jannaschii this enzyme is involved in conversion of 5-phospho-D-ribose-1-pyrophosphate to ribulose-1,5-bisphosphate using NAD as a cofactor; part of RubisCO pathway; ribulose-1,5-biphosphate synthetase 1577513..1578289 Thermosipho melanesiensis BI429 5296846 YP_001306820.1 CDS Tmel_1591 NC_009616.1 1578409 1578834 D hypothetical protein 1578409..1578834 Thermosipho melanesiensis BI429 5297289 YP_001306821.1 CDS Tmel_1592 NC_009616.1 1579059 1580336 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 1579059..1580336 Thermosipho melanesiensis BI429 5297290 YP_001306822.1 CDS Tmel_1593 NC_009616.1 1580333 1581049 D PFAM: Xylose isomerase domain protein TIM barrel; xylose isomerase domain-containing protein 1580333..1581049 Thermosipho melanesiensis BI429 5297922 YP_001306823.1 CDS Tmel_1594 NC_009616.1 1581049 1582248 D PFAM: Phosphomethylpyrimidine kinase type-1; phosphomethylpyrimidine kinase type-1 1581049..1582248 Thermosipho melanesiensis BI429 5296760 YP_001306824.1 CDS Tmel_1595 NC_009616.1 1582349 1583308 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1582349..1583308 Thermosipho melanesiensis BI429 5296761 YP_001306825.1 CDS Tmel_1596 NC_009616.1 1583305 1584615 D PFAM: amidohydrolase; Amidohydrolase 3; amidohydrolase 3 1583305..1584615 Thermosipho melanesiensis BI429 5297541 YP_001306826.1 CDS Tmel_1597 NC_009616.1 1584588 1585613 R catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase complement(1584588..1585613) Thermosipho melanesiensis BI429 5297542 YP_001306827.1 CDS Tmel_1598 NC_009616.1 1585579 1585848 R hypothetical protein complement(1585579..1585848) Thermosipho melanesiensis BI429 5297878 YP_001306828.1 CDS thiH NC_009616.1 1585835 1587250 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain; thiamine biosynthesis protein ThiH complement(1585835..1587250) Thermosipho melanesiensis BI429 5297879 YP_001306829.1 CDS Tmel_1600 NC_009616.1 1587252 1587503 R hypothetical protein complement(1587252..1587503) Thermosipho melanesiensis BI429 5296970 YP_001306830.1 CDS Tmel_1601 NC_009616.1 1587637 1589385 R TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; hydrogenase, Fe-only complement(1587637..1589385) Thermosipho melanesiensis BI429 5297734 YP_001306831.1 CDS Tmel_1602 NC_009616.1 1589567 1590448 R PFAM: Auxin Efflux Carrier; auxin efflux carrier complement(1589567..1590448) Thermosipho melanesiensis BI429 5297735 YP_001306832.1 CDS Tmel_1603 NC_009616.1 1590445 1590693 R hypothetical protein complement(1590445..1590693) Thermosipho melanesiensis BI429 5297266 YP_001306833.1 CDS Tmel_1604 NC_009616.1 1590683 1591378 R PFAM: ribonuclease III; double-stranded RNA binding domain protein; ribonuclease III complement(1590683..1591378) Thermosipho melanesiensis BI429 5297267 YP_001306834.1 CDS Tmel_1605 NC_009616.1 1591297 1592325 R PFAM: ExsB family protein; ExsB family protein complement(1591297..1592325) Thermosipho melanesiensis BI429 5297099 YP_001306835.1 CDS Tmel_1606 NC_009616.1 1592327 1593010 R TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin--acetyl-CoA-carboxylase ligase complement(1592327..1593010) Thermosipho melanesiensis BI429 5297100 YP_001306836.1 CDS Tmel_1607 NC_009616.1 1592994 1594403 R TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; integral membrane protein MviN complement(1592994..1594403) Thermosipho melanesiensis BI429 5296820 YP_001306837.1 CDS Tmel_1608 NC_009616.1 1594512 1594790 D PFAM: Fe-S cluster domain protein; Fe-S cluster domain-containing protein 1594512..1594790 Thermosipho melanesiensis BI429 5297589 YP_001306838.1 CDS Tmel_1609 NC_009616.1 1594796 1595590 D TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; DNA protecting protein DprA 1594796..1595590 Thermosipho melanesiensis BI429 5297590 YP_001306839.1 CDS panC NC_009616.1 1595568 1596410 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 1595568..1596410 Thermosipho melanesiensis BI429 5297188 YP_001306840.1 CDS Tmel_1611 NC_009616.1 1596417 1598525 D PFAM: glycoside hydrolase, family 31; Alpha-glucosidase 1596417..1598525 Thermosipho melanesiensis BI429 5297189 YP_001306841.1 CDS Tmel_1612 NC_009616.1 1598537 1600636 D PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein; polynucleotide phosphorylase/polyadenylase 1598537..1600636 Thermosipho melanesiensis BI429 5296783 YP_001306842.1 CDS Tmel_1613 NC_009616.1 1600633 1601883 D PFAM: peptidase M16 domain protein; peptidase M16 domain-containing protein 1600633..1601883 Thermosipho melanesiensis BI429 5296784 YP_001306843.1 CDS Tmel_1614 NC_009616.1 1601880 1602875 D PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1601880..1602875 Thermosipho melanesiensis BI429 5297909 YP_001306844.1 CDS hslU NC_009616.1 1602868 1604265 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1602868..1604265 Thermosipho melanesiensis BI429 5297467 YP_001306845.1 CDS Tmel_1616 NC_009616.1 1604276 1605565 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1604276..1605565 Thermosipho melanesiensis BI429 5297468 YP_001306846.1 CDS Tmel_1617 NC_009616.1 1605577 1607088 D hypothetical protein 1605577..1607088 Thermosipho melanesiensis BI429 5297895 YP_001306847.1 CDS Tmel_1618 NC_009616.1 1607131 1607727 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1607131..1607727 Thermosipho melanesiensis BI429 5297896 YP_001306848.1 CDS Tmel_1619 NC_009616.1 1607746 1608396 D similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1607746..1608396 Thermosipho melanesiensis BI429 5297082 YP_001306849.1 CDS aspS NC_009616.1 1608402 1610147 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1608402..1610147 Thermosipho melanesiensis BI429 5297083 YP_001306850.1 CDS Tmel_1621 NC_009616.1 1610128 1610460 D TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; anti-sigma-factor antagonist 1610128..1610460 Thermosipho melanesiensis BI429 5297630 YP_001306851.1 CDS cmk NC_009616.1 1610469 1611122 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1610469..1611122 Thermosipho melanesiensis BI429 5296824 YP_001306852.1 CDS Tmel_1623 NC_009616.1 1611110 1613542 D these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain-containing protein 1611110..1613542 Thermosipho melanesiensis BI429 5296825 YP_001306853.1 CDS engA NC_009616.1 1613511 1614824 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1613511..1614824 Thermosipho melanesiensis BI429 5297716 YP_001306854.1 CDS Tmel_1625 NC_009616.1 1614839 1615900 D PFAM: basic membrane lipoprotein; basic membrane lipoprotein 1614839..1615900 Thermosipho melanesiensis BI429 5297717 YP_001306855.1 CDS Tmel_1626 NC_009616.1 1615913 1616839 D hypothetical protein 1615913..1616839 Thermosipho melanesiensis BI429 5297755 YP_001306856.1 CDS Tmel_1627 NC_009616.1 1616841 1618253 D TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase 1616841..1618253 Thermosipho melanesiensis BI429 5297756 YP_001306857.1 CDS rpmH NC_009616.1 1618314 1618448 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1618314..1618448 Thermosipho melanesiensis BI429 5297241 YP_001306858.1 CDS Tmel_1629 NC_009616.1 1618430 1618825 D TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein; ribonuclease P protein component 1618430..1618825 Thermosipho melanesiensis BI429 5297966 YP_001306859.1 CDS Tmel_1630 NC_009616.1 1618797 1619042 D PFAM: protein of unknown function DUF37; hypothetical protein 1618797..1619042 Thermosipho melanesiensis BI429 5297967 YP_001306860.1 CDS Tmel_1631 NC_009616.1 1619039 1620340 D PFAM: 60 kDa inner membrane insertion protein; 60 kDa inner membrane insertion protein 1619039..1620340 Thermosipho melanesiensis BI429 5298228 YP_001306861.1 CDS Tmel_1632 NC_009616.1 1620346 1621017 D PFAM: single-stranded nucleic acid binding R3H domain protein; single-stranded nucleic acid binding R3H domain-containing protein 1620346..1621017 Thermosipho melanesiensis BI429 5298229 YP_001306862.1 CDS Tmel_1633 NC_009616.1 1620971 1621312 D PFAM: Cupin 2, conserved barrel domain protein; cupin 2 domain-containing protein 1620971..1621312 Thermosipho melanesiensis BI429 5298209 YP_001306863.1 CDS Tmel_1634 NC_009616.1 1621305 1622324 D PFAM: TrkA-N domain protein; TrkA-C domain protein; Ion transport 2 domain protein; TrkA domain-containing protein 1621305..1622324 Thermosipho melanesiensis BI429 5298210 YP_001306864.1 CDS Tmel_1635 NC_009616.1 1622497 1623867 D TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp; glutamine synthetase, type I 1622497..1623867 Thermosipho melanesiensis BI429 5297964 YP_001306865.1 CDS Tmel_1636 NC_009616.1 1623967 1625364 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; response regulator receiver modulated diguanylate cyclase 1623967..1625364 Thermosipho melanesiensis BI429 5297923 YP_001306866.1 CDS Tmel_1637 NC_009616.1 1625361 1626413 D PFAM: Endonuclease/exonuclease/phosphatase; endonuclease/exonuclease/phosphatase 1625361..1626413 Thermosipho melanesiensis BI429 5297924 YP_001306867.1 CDS Tmel_1638 NC_009616.1 1626423 1627742 D PFAM: glycoside hydrolase, family 1; beta-glucosidase 1626423..1627742 Thermosipho melanesiensis BI429 5297912 YP_001306868.1 CDS Tmel_1639 NC_009616.1 1627739 1628194 R hypothetical protein complement(1627739..1628194) Thermosipho melanesiensis BI429 5297913 YP_001306869.1 CDS Tmel_1640 NC_009616.1 1628275 1629096 D hypothetical protein 1628275..1629096 Thermosipho melanesiensis BI429 5297893 YP_001306870.1 CDS Tmel_1641 NC_009616.1 1629082 1630002 R hypothetical protein complement(1629082..1630002) Thermosipho melanesiensis BI429 5297894 YP_001306871.1 CDS Tmel_1642 NC_009616.1 1630093 1631208 D PFAM: YhhN family protein; YhhN family protein 1630093..1631208 Thermosipho melanesiensis BI429 5297554 YP_001306872.1 CDS Tmel_1643 NC_009616.1 1631221 1632000 D PFAM: protein of unknown function DUF152; hypothetical protein 1631221..1632000 Thermosipho melanesiensis BI429 5296945 YP_001306873.1 CDS Tmel_1644 NC_009616.1 1632234 1633379 R hypothetical protein complement(1632234..1633379) Thermosipho melanesiensis BI429 5296946 YP_001306874.1 CDS Tmel_1645 NC_009616.1 1633576 1633845 D PFAM: glutaredoxin 2; glutaredoxin 2 1633576..1633845 Thermosipho melanesiensis BI429 5297684 YP_001306875.1 CDS Tmel_1646 NC_009616.1 1633903 1634769 D PFAM: protein of unknown function DUF6, transmembrane; hypothetical protein 1633903..1634769 Thermosipho melanesiensis BI429 5297685 YP_001306876.1 CDS Tmel_1647 NC_009616.1 1635085 1636017 R hypothetical protein complement(1635085..1636017) Thermosipho melanesiensis BI429 5297135 YP_001306877.1 CDS Tmel_1648 NC_009616.1 1636022 1636756 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1636022..1636756) Thermosipho melanesiensis BI429 5297136 YP_001306878.1 CDS Tmel_1649 NC_009616.1 1636756 1637712 R multidrug ABC transporter ATPase and permease components-like protein complement(1636756..1637712) Thermosipho melanesiensis BI429 5297957 YP_001306879.1 CDS Tmel_1650 NC_009616.1 1640173 1640433 D TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein 1640173..1640433 Thermosipho melanesiensis BI429 5297591 YP_001306880.1 CDS Tmel_1651 NC_009616.1 1640446 1641432 D TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; CRISPR-associated Cas1 family protein 1640446..1641432 Thermosipho melanesiensis BI429 5297592 YP_001306881.1 CDS Tmel_1652 NC_009616.1 1641429 1641707 D TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; CRISPR-associated Cas2 family protein 1641429..1641707 Thermosipho melanesiensis BI429 5298323 YP_001306882.1 CDS Tmel_1653 NC_009616.1 1641942 1642049 D hypothetical protein 1641942..1642049 Thermosipho melanesiensis BI429 5298324 YP_001306883.1 CDS Tmel_1654 NC_009616.1 1642056 1642244 D hypothetical protein 1642056..1642244 Thermosipho melanesiensis BI429 5298356 YP_001306884.1 CDS Tmel_1655 NC_009616.1 1642292 1642474 D hypothetical protein 1642292..1642474 Thermosipho melanesiensis BI429 5298357 YP_001306885.1 CDS Tmel_1656 NC_009616.1 1642545 1643672 D TIGRFAM: putative CRISPR-associated protein, APE2256 family; CRISPR-associated protein APE2256 family 1642545..1643672 Thermosipho melanesiensis BI429 5298199 YP_001306886.1 CDS Tmel_1657 NC_009616.1 1643708 1644832 D TIGRFAM: CRISPR-associated RAMP protein, Cmr1 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr1 family protein 1643708..1644832 Thermosipho melanesiensis BI429 5298178 YP_001306887.1 CDS Tmel_1658 NC_009616.1 1644849 1647044 D TIGRFAM: CRISPR-associated protein, Crm2 family; CRISPR-associated RAMP Crm2 family protein 1644849..1647044 Thermosipho melanesiensis BI429 5298179 YP_001306888.1 CDS Tmel_1659 NC_009616.1 1647034 1648005 D TIGRFAM: CRISPR-associated protein, Cmr3 family; CRISPR-associated Cmr3 family protein 1647034..1648005 Thermosipho melanesiensis BI429 5298126 YP_001306889.1 CDS Tmel_1660 NC_009616.1 1648018 1648848 D TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr4 family protein 1648018..1648848 Thermosipho melanesiensis BI429 5298127 YP_001306890.1 CDS Tmel_1661 NC_009616.1 1648858 1649229 D TIGRFAM: CRISPR-associated protein, Cmr5 family; CRISPR-associated Cmr5 family protein 1648858..1649229 Thermosipho melanesiensis BI429 5298003 YP_001306891.1 CDS Tmel_1662 NC_009616.1 1649247 1650062 D TIGRFAM: CRISPR-associated RAMP protein, Cmr6 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Cmr6 family protein 1649247..1650062 Thermosipho melanesiensis BI429 5298004 YP_001306892.1 CDS Tmel_1664 NC_009616.1 1652445 1652582 D hypothetical protein 1652445..1652582 Thermosipho melanesiensis BI429 5297877 YP_001306893.1 CDS Tmel_1665 NC_009616.1 1653099 1653404 D hypothetical protein 1653099..1653404 Thermosipho melanesiensis BI429 5298171 YP_001306894.1 CDS Tmel_1666 NC_009616.1 1653413 1654078 D ECF subfamily RNA polymerase sigma-24 factor 1653413..1654078 Thermosipho melanesiensis BI429 5298172 YP_001306895.1 CDS Tmel_1667 NC_009616.1 1654097 1654867 D hypothetical protein 1654097..1654867 Thermosipho melanesiensis BI429 5298106 YP_001306896.1 CDS Tmel_1668 NC_009616.1 1654867 1656300 D hypothetical protein 1654867..1656300 Thermosipho melanesiensis BI429 5298107 YP_001306897.1 CDS Tmel_1669 NC_009616.1 1656302 1657708 D TIGRFAM: CRISPR-associated protein, MJ1666 family; CRISPR-associated DxTHG family protein 1656302..1657708 Thermosipho melanesiensis BI429 5298063 YP_001306898.1 CDS Tmel_1670 NC_009616.1 1657721 1659994 D TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: metal-dependent phosphohydrolase, HD sub domain; metal dependent phosphohydrolase 1657721..1659994 Thermosipho melanesiensis BI429 5298064 YP_001306899.1 CDS Tmel_1671 NC_009616.1 1659996 1660436 D TIGRFAM: CRISPR-associated protein, Csm2 family; CRISPR-associated Csm2 family protein 1659996..1660436 Thermosipho melanesiensis BI429 5298387 YP_001306900.1 CDS Tmel_1672 NC_009616.1 1660453 1661262 D TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm3 family protein 1660453..1661262 Thermosipho melanesiensis BI429 5298279 YP_001306901.1 CDS Tmel_1673 NC_009616.1 1661267 1662208 D TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm4 family protein 1661267..1662208 Thermosipho melanesiensis BI429 5298280 YP_001306902.1 CDS Tmel_1674 NC_009616.1 1662198 1663259 D TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; CRISPR-associated RAMP Csm5 family protein 1662198..1663259 Thermosipho melanesiensis BI429 5298255 YP_001306903.1 CDS Tmel_1675 NC_009616.1 1663256 1663846 D hypothetical protein 1663256..1663846 Thermosipho melanesiensis BI429 5298256 YP_001306904.1 CDS Tmel_1676 NC_009616.1 1663824 1664555 D TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; CRISPR-associated Cas family protein 1663824..1664555 Thermosipho melanesiensis BI429 5298392 YP_001306905.1 CDS Tmel_1677 NC_009616.1 1664566 1665003 D PFAM: ribonuclease H; ribonuclease H 1664566..1665003 Thermosipho melanesiensis BI429 5298393 YP_001306906.1 CDS Tmel_1678 NC_009616.1 1665520 1665831 D hypothetical protein 1665520..1665831 Thermosipho melanesiensis BI429 5298196 YP_001306907.1 CDS Tmel_1679 NC_009616.1 1666141 1666356 D hypothetical protein 1666141..1666356 Thermosipho melanesiensis BI429 5298181 YP_001306908.1 CDS Tmel_1681 NC_009616.1 1666829 1667047 D hypothetical protein 1666829..1667047 Thermosipho melanesiensis BI429 5296479 YP_001306909.1 CDS Tmel_1682 NC_009616.1 1667116 1667712 R TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; protein-L-isoaspartate O-methyltransferase complement(1667116..1667712) Thermosipho melanesiensis BI429 5298154 YP_001306910.1 CDS Tmel_1683 NC_009616.1 1667978 1669348 D PFAM: DUF234 DEXX-box ATPase; ATPase; ATPase 1667978..1669348 Thermosipho melanesiensis BI429 5298155 YP_001306911.1 CDS Tmel_1684 NC_009616.1 1669485 1669898 D PFAM: protein of unknown function DUF262; hypothetical protein 1669485..1669898 Thermosipho melanesiensis BI429 5298440 YP_001306912.1 CDS Tmel_1685 NC_009616.1 1669947 1671743 D hypothetical protein 1669947..1671743 Thermosipho melanesiensis BI429 5298441 YP_001306913.1 CDS Tmel_1686 NC_009616.1 1671833 1673929 D PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; type III restriction enzyme, res subunit 1671833..1673929 Thermosipho melanesiensis BI429 5298142 YP_001306914.1 CDS Tmel_1687 NC_009616.1 1673945 1674148 D hypothetical protein 1673945..1674148 Thermosipho melanesiensis BI429 5298366 YP_001306915.1 CDS Tmel_1688 NC_009616.1 1674154 1675437 D hypothetical protein 1674154..1675437 Thermosipho melanesiensis BI429 5298367 YP_001306916.1 CDS Tmel_1689 NC_009616.1 1675415 1675705 D hypothetical protein 1675415..1675705 Thermosipho melanesiensis BI429 5298360 YP_001306917.1 CDS Tmel_1690 NC_009616.1 1675699 1676106 D hypothetical protein 1675699..1676106 Thermosipho melanesiensis BI429 5298361 YP_001306918.1 CDS Tmel_1691 NC_009616.1 1676099 1678639 D PFAM: DNA methylase N-4/N-6 domain protein; DNA methylase N-4/N-6 domain-containing protein 1676099..1678639 Thermosipho melanesiensis BI429 5298200 YP_001306919.1 CDS Tmel_1692 NC_009616.1 1678644 1681568 D PFAM: type III restriction enzyme, res subunit; type III restriction enzyme, res subunit 1678644..1681568 Thermosipho melanesiensis BI429 5298201 YP_001306920.1 CDS Tmel_1694 NC_009616.1 1682033 1682326 D PFAM: DNA polymerase, beta domain protein region; DNA polymerase subunit beta 1682033..1682326 Thermosipho melanesiensis BI429 5296480 YP_001306921.1 CDS Tmel_1695 NC_009616.1 1682323 1682670 D PFAM: protein of unknown function DUF86; hypothetical protein 1682323..1682670 Thermosipho melanesiensis BI429 5298031 YP_001306922.1 CDS Tmel_1697 NC_009616.1 1683001 1683360 D hypothetical protein 1683001..1683360 Thermosipho melanesiensis BI429 5297969 YP_001306923.1 CDS Tmel_1699 NC_009616.1 1684449 1685714 R PFAM: Arsenical pump membrane protein; Citrate transporter; citrate transporter complement(1684449..1685714) Thermosipho melanesiensis BI429 5297970 YP_001306924.1 CDS Tmel_1700 NC_009616.1 1685964 1686233 D PFAM: glutaredoxin 2; glutaredoxin 2 1685964..1686233 Thermosipho melanesiensis BI429 5298241 YP_001306925.1 CDS Tmel_1701 NC_009616.1 1686311 1687606 R PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase complement(1686311..1687606) Thermosipho melanesiensis BI429 5298252 YP_001306926.1 CDS Tmel_1702 NC_009616.1 1687603 1688703 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein complement(1687603..1688703) Thermosipho melanesiensis BI429 5298253 YP_001306927.1 CDS Tmel_1703 NC_009616.1 1688748 1690028 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1688748..1690028) Thermosipho melanesiensis BI429 5298254 YP_001306928.1 CDS Tmel_1704 NC_009616.1 1690028 1690897 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1690028..1690897) Thermosipho melanesiensis BI429 5298244 YP_001306929.1 CDS Tmel_1705 NC_009616.1 1690972 1691823 R sugar ABC transporter periplasmic component-like protein complement(1690972..1691823) Thermosipho melanesiensis BI429 5298245 YP_001306930.1 CDS Tmel_1706 NC_009616.1 1691857 1692180 R hypothetical protein complement(1691857..1692180) Thermosipho melanesiensis BI429 5298246 YP_001306931.1 CDS Tmel_1707 NC_009616.1 1692348 1693040 D hypothetical protein 1692348..1693040 Thermosipho melanesiensis BI429 5298247 YP_001306932.1 CDS Tmel_1708 NC_009616.1 1693391 1694155 R PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(1693391..1694155) Thermosipho melanesiensis BI429 5298434 YP_001306933.1 CDS Tmel_1709 NC_009616.1 1694348 1694680 R PFAM: protein of unknown function DUF1291; hypothetical protein complement(1694348..1694680) Thermosipho melanesiensis BI429 5298435 YP_001306934.1 CDS Tmel_1710 NC_009616.1 1694677 1695393 R PFAM: DNA alkylation repair enzyme; DNA alkylation repair enzyme complement(1694677..1695393) Thermosipho melanesiensis BI429 5298010 YP_001306935.1 CDS Tmel_1711 NC_009616.1 1695680 1696744 R TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; protein phosphatase 2C domain protein; putative PAS/PAC sensor protein complement(1695680..1696744) Thermosipho melanesiensis BI429 5298466 YP_001306936.1 CDS Tmel_1712 NC_009616.1 1697471 1698163 R hypothetical protein complement(1697471..1698163) Thermosipho melanesiensis BI429 5298467 YP_001306937.1 CDS Tmel_1713 NC_009616.1 1698350 1699558 D PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein 1698350..1699558 Thermosipho melanesiensis BI429 5297050 YP_001306938.1 CDS Tmel_1714 NC_009616.1 1699609 1700478 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1699609..1700478 Thermosipho melanesiensis BI429 5297051 YP_001306939.1 CDS Tmel_1715 NC_009616.1 1700478 1701758 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1700478..1701758 Thermosipho melanesiensis BI429 5297443 YP_001306940.1 CDS Tmel_1716 NC_009616.1 1701789 1702886 D PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; ABC transporter-like protein 1701789..1702886 Thermosipho melanesiensis BI429 5297444 YP_001306941.1 CDS Tmel_1717 NC_009616.1 1702886 1704187 D PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1702886..1704187 Thermosipho melanesiensis BI429 5297636 YP_001306942.1 CDS Tmel_1718 NC_009616.1 1704236 1704511 R hypothetical protein complement(1704236..1704511) Thermosipho melanesiensis BI429 5298075 YP_001306943.1 CDS Tmel_1719 NC_009616.1 1704541 1704870 R hypothetical protein complement(1704541..1704870) Thermosipho melanesiensis BI429 5298076 YP_001306944.1 CDS Tmel_1720 NC_009616.1 1705312 1705983 D P-loop ATPase-like protein 1705312..1705983 Thermosipho melanesiensis BI429 5298460 YP_001306945.1 CDS Tmel_1721 NC_009616.1 1706028 1706354 D hypothetical protein 1706028..1706354 Thermosipho melanesiensis BI429 5298461 YP_001306946.1 CDS Tmel_1722 NC_009616.1 1706735 1707493 D PFAM: protein of unknown function DUF81; hypothetical protein 1706735..1707493 Thermosipho melanesiensis BI429 5297319 YP_001306947.1 CDS Tmel_1723 NC_009616.1 1707511 1708908 D TIGRFAM: dipeptidase, putative; PFAM: peptidase M20; dipeptidase 1707511..1708908 Thermosipho melanesiensis BI429 5297320 YP_001306948.1 CDS Tmel_1724 NC_009616.1 1709480 1710688 R hypothetical protein complement(1709480..1710688) Thermosipho melanesiensis BI429 5297511 YP_001306949.1 CDS Tmel_1725 NC_009616.1 1710856 1711422 D hypothetical protein 1710856..1711422 Thermosipho melanesiensis BI429 5296706 YP_001306950.1 CDS Tmel_1726 NC_009616.1 1711484 1713208 R PFAM: penicillin-binding protein, transpeptidase; peptidoglycan glycosyltransferase complement(1711484..1713208) Thermosipho melanesiensis BI429 5296707 YP_001306951.1 CDS mraW NC_009616.1 1713481 1714356 R TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; S-adenosyl-methyltransferase MraW complement(1713481..1714356) Thermosipho melanesiensis BI429 5296650 YP_001306952.1 CDS Tmel_1728 NC_009616.1 1714531 1715889 R PFAM: amidohydrolase; hydroxydechloroatrazine ethylaminohydrolase complement(1714531..1715889) Thermosipho melanesiensis BI429 5296651 YP_001306953.1 CDS Tmel_1729 NC_009616.1 1715900 1717312 R PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; pyridoxal-5'-phosphate-dependent enzyme subunit beta complement(1715900..1717312) Thermosipho melanesiensis BI429 5296631 YP_001306954.1 CDS Tmel_1730 NC_009616.1 1717317 1719581 R PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase complement(1717317..1719581) Thermosipho melanesiensis BI429 5296632 YP_001306955.1 CDS Tmel_1731 NC_009616.1 1719585 1721309 R TIGRFAM: adenine deaminase; PFAM: amidohydrolase; adenine deaminase complement(1719585..1721309) Thermosipho melanesiensis BI429 5297092 YP_001306956.1 CDS Tmel_1732 NC_009616.1 1721545 1722684 R TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase complement(1721545..1722684) Thermosipho melanesiensis BI429 5297093 YP_001306957.1 CDS Tmel_1733 NC_009616.1 1722681 1723697 R TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase complement(1722681..1723697) Thermosipho melanesiensis BI429 5297199 YP_001306958.1 CDS Tmel_1734 NC_009616.1 1723711 1724625 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1723711..1724625) Thermosipho melanesiensis BI429 5297355 YP_001306959.1 CDS Tmel_1735 NC_009616.1 1724640 1725677 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1724640..1725677) Thermosipho melanesiensis BI429 5297356 YP_001306960.1 CDS uvrC NC_009616.1 1725799 1727451 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1725799..1727451) Thermosipho melanesiensis BI429 5297078 YP_001306961.1 CDS Tmel_1737 NC_009616.1 1727514 1727954 R hypothetical protein complement(1727514..1727954) Thermosipho melanesiensis BI429 5297079 YP_001306962.1 CDS Tmel_1738 NC_009616.1 1727954 1728322 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(1727954..1728322) Thermosipho melanesiensis BI429 5296697 YP_001306963.1 CDS Tmel_1739 NC_009616.1 1728426 1730366 R TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; ferrous iron transport protein B complement(1728426..1730366) Thermosipho melanesiensis BI429 5296698 YP_001306964.1 CDS Tmel_1740 NC_009616.1 1730368 1730796 R PFAM: FeoA family protein; FeoA family protein complement(1730368..1730796) Thermosipho melanesiensis BI429 5296722 YP_001306965.1 CDS Tmel_1741 NC_009616.1 1731267 1731821 R TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1; helix-hairpin-helix repeat-containing competence protein ComEA complement(1731267..1731821) Thermosipho melanesiensis BI429 5296723 YP_001306966.1 CDS Tmel_1742 NC_009616.1 1731815 1732603 R PFAM: protein of unknown function DUF52; hypothetical protein complement(1731815..1732603) Thermosipho melanesiensis BI429 5297288 YP_001306967.1 CDS Tmel_1743 NC_009616.1 1732603 1736511 R PFAM: type II and III secretion system protein; type II and III secretion system protein complement(1732603..1736511) Thermosipho melanesiensis BI429 5297597 YP_001306968.1 CDS Tmel_1744 NC_009616.1 1736511 1736957 R hypothetical protein complement(1736511..1736957) Thermosipho melanesiensis BI429 5297598 YP_001306969.1 CDS Tmel_1745 NC_009616.1 1736950 1737375 R hypothetical protein complement(1736950..1737375) Thermosipho melanesiensis BI429 5297180 YP_001306970.1 CDS Tmel_1746 NC_009616.1 1737372 1737929 R hypothetical protein complement(1737372..1737929) Thermosipho melanesiensis BI429 5297181 YP_001306971.1 CDS Tmel_1747 NC_009616.1 1737907 1738851 R hypothetical protein complement(1737907..1738851) Thermosipho melanesiensis BI429 5297706 YP_001306972.1 CDS Tmel_1748 NC_009616.1 1738862 1739218 R hypothetical protein complement(1738862..1739218) Thermosipho melanesiensis BI429 5297707 YP_001306973.1 CDS Tmel_1749 NC_009616.1 1739220 1740413 R PFAM: type II secretion system protein; type II secretion system protein complement(1739220..1740413) Thermosipho melanesiensis BI429 5297562 YP_001306974.1 CDS Tmel_1750 NC_009616.1 1740403 1741083 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1740403..1741083) Thermosipho melanesiensis BI429 5297563 YP_001306975.1 CDS Tmel_1751 NC_009616.1 1741080 1741676 R PFAM: methyltransferase small; Methyltransferase type 12; methyltransferase small complement(1741080..1741676) Thermosipho melanesiensis BI429 5296587 YP_001306976.1 CDS Tmel_1752 NC_009616.1 1741676 1742134 R PFAM: flavin reductase domain protein, FMN-binding; flavin reductase domain-containing protein complement(1741676..1742134) Thermosipho melanesiensis BI429 5297097 YP_001306977.1 CDS Tmel_1753 NC_009616.1 1742269 1744125 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1742269..1744125 Thermosipho melanesiensis BI429 5297098 YP_001306978.1 CDS Tmel_1754 NC_009616.1 1744164 1744565 R hypothetical protein complement(1744164..1744565) Thermosipho melanesiensis BI429 5297264 YP_001306979.1 CDS rpsT NC_009616.1 1744580 1744855 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1744580..1744855) Thermosipho melanesiensis BI429 5297265 YP_001306980.1 CDS Tmel_1756 NC_009616.1 1744873 1746060 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1744873..1746060) Thermosipho melanesiensis BI429 5297168 YP_001306981.1 CDS Tmel_1757 NC_009616.1 1746057 1746371 R hypothetical protein complement(1746057..1746371) Thermosipho melanesiensis BI429 5297169 YP_001306982.1 CDS Tmel_1758 NC_009616.1 1746374 1747339 R PFAM: peptidase M23B; peptidase M23B complement(1746374..1747339) Thermosipho melanesiensis BI429 5296835 YP_001306983.1 CDS Tmel_1759 NC_009616.1 1747336 1748421 R TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; small GTP-binding protein complement(1747336..1748421) Thermosipho melanesiensis BI429 5296836 YP_001306984.1 CDS Tmel_1760 NC_009616.1 1748408 1748668 R TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; RNA chaperone Hfq complement(1748408..1748668) Thermosipho melanesiensis BI429 5297075 YP_001306985.1 CDS Tmel_1761 NC_009616.1 1748671 1749105 R hypothetical protein complement(1748671..1749105) Thermosipho melanesiensis BI429 5296837 YP_001306986.1 CDS Tmel_1762 NC_009616.1 1749102 1750001 R hypothetical protein complement(1749102..1750001) Thermosipho melanesiensis BI429 5296838 YP_001306987.1 CDS Tmel_1763 NC_009616.1 1749998 1751677 R PFAM: phosphoribulokinase/uridine kinase; phosphoribulokinase/uridine kinase complement(1749998..1751677) Thermosipho melanesiensis BI429 5297493 YP_001306988.1 CDS Tmel_1764 NC_009616.1 1751690 1753087 R TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; ribonuclease complement(1751690..1753087) Thermosipho melanesiensis BI429 5297494 YP_001306989.1 CDS Tmel_1765 NC_009616.1 1753092 1754291 R catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase complement(1753092..1754291) Thermosipho melanesiensis BI429 5296565 YP_001306990.1 CDS Tmel_1766 NC_009616.1 1754468 1754980 D PFAM: CMP/dCMP deaminase, zinc-binding; zinc-binding CMP/dCMP deaminase 1754468..1754980 Thermosipho melanesiensis BI429 5296566 YP_001306991.1 CDS Tmel_1767 NC_009616.1 1754967 1755791 D catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1754967..1755791 Thermosipho melanesiensis BI429 5297059 YP_001306992.1 CDS Tmel_1768 NC_009616.1 1755795 1756397 D TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase subunit gamma 1755795..1756397 Thermosipho melanesiensis BI429 5297060 YP_001306993.1 CDS Tmel_1769 NC_009616.1 1756384 1756833 D PFAM: diacylglycerol kinase; diacylglycerol kinase 1756384..1756833 Thermosipho melanesiensis BI429 5296967 YP_001306994.1 CDS Tmel_1770 NC_009616.1 1756818 1757852 D regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1756818..1757852 Thermosipho melanesiensis BI429 5297339 YP_001306995.1 CDS Tmel_1771 NC_009616.1 1757867 1758952 D PFAM: S-layer domain protein domain protein; S-layer domain-containing protein 1757867..1758952 Thermosipho melanesiensis BI429 5297340 YP_001306996.1 CDS Tmel_1776 NC_009616.1 1764394 1766388 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(1764394..1766388) Thermosipho melanesiensis BI429 5297941 YP_001306997.1 CDS Tmel_1777 NC_009616.1 1766385 1767902 R catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase complement(1766385..1767902) Thermosipho melanesiensis BI429 5297345 YP_001306998.1 CDS Tmel_1778 NC_009616.1 1767899 1768420 R TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; ATP--cobalamin adenosyltransferase complement(1767899..1768420) Thermosipho melanesiensis BI429 5296714 YP_001306999.1 CDS Tmel_1779 NC_009616.1 1768420 1769163 R hypothetical protein complement(1768420..1769163) Thermosipho melanesiensis BI429 5296715 YP_001307000.1 CDS Tmel_1780 NC_009616.1 1769166 1769897 R hypothetical protein complement(1769166..1769897) Thermosipho melanesiensis BI429 5296512 YP_001307001.1 CDS Tmel_1781 NC_009616.1 1769902 1770411 R PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase complement(1769902..1770411) Thermosipho melanesiensis BI429 5296513 YP_001307002.1 CDS Tmel_1782 NC_009616.1 1770401 1771216 R PFAM: metallophosphoesterase; metallophosphoesterase complement(1770401..1771216) Thermosipho melanesiensis BI429 5297010 YP_001307003.1 CDS Tmel_1783 NC_009616.1 1771213 1771443 R hypothetical protein complement(1771213..1771443) Thermosipho melanesiensis BI429 5296914 YP_001307004.1 CDS Tmel_1784 NC_009616.1 1771433 1771930 R PFAM: iron dependent repressor; iron dependent repressor complement(1771433..1771930) Thermosipho melanesiensis BI429 5296915 YP_001307005.1 CDS Tmel_1785 NC_009616.1 1771969 1773000 R PFAM: peptidase M42 family protein; peptidase M42 family protein complement(1771969..1773000) Thermosipho melanesiensis BI429 5296912 YP_001307006.1 CDS Tmel_1786 NC_009616.1 1773001 1773648 R hypothetical protein complement(1773001..1773648) Thermosipho melanesiensis BI429 5296913 YP_001307007.1 CDS Tmel_1787 NC_009616.1 1773645 1773899 R hypothetical protein complement(1773645..1773899) Thermosipho melanesiensis BI429 5297461 YP_001307008.1 CDS Tmel_1788 NC_009616.1 1773896 1774141 R hypothetical protein complement(1773896..1774141) Thermosipho melanesiensis BI429 5297462 YP_001307009.1 CDS Tmel_1789 NC_009616.1 1774143 1774487 R hypothetical protein complement(1774143..1774487) Thermosipho melanesiensis BI429 5297239 YP_001307010.1 CDS Tmel_1790 NC_009616.1 1774475 1775446 R PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; glycerol-3-phosphate dehydrogenase complement(1774475..1775446) Thermosipho melanesiensis BI429 5297240 YP_001307011.1 CDS Tmel_1791 NC_009616.1 1775443 1776378 R TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: putative methyltransferase; tRNA (guanine-N(7)-)-methyltransferase complement(1775443..1776378) Thermosipho melanesiensis BI429 5297031 YP_001307012.1 CDS Tmel_1792 NC_009616.1 1776375 1777478 R PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein complement(1776375..1777478) Thermosipho melanesiensis BI429 5296892 YP_001307013.1 CDS Tmel_1793 NC_009616.1 1777481 1778986 R TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; carbohydrate kinase, YjeF-like protein complement(1777481..1778986) Thermosipho melanesiensis BI429 5296893 YP_001307014.1 CDS Tmel_1794 NC_009616.1 1778989 1779447 R PFAM: Lytic transglycosylase, catalytic; lytic transglycosylase complement(1778989..1779447) Thermosipho melanesiensis BI429 5297514 YP_001307015.1 CDS Tmel_1795 NC_009616.1 1779458 1780156 R PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; peptidase A24A domain-containing protein complement(1779458..1780156) Thermosipho melanesiensis BI429 5297515 YP_001307016.1 CDS Tmel_1796 NC_009616.1 1780141 1781199 R PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; TPR repeat-containing protein complement(1780141..1781199) Thermosipho melanesiensis BI429 5297714 YP_001307017.1 CDS Tmel_1797 NC_009616.1 1781355 1782713 D TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; protease Do 1781355..1782713 Thermosipho melanesiensis BI429 5297715 YP_001307018.1 CDS Tmel_1798 NC_009616.1 1782906 1785392 D TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35; glycogen/starch/alpha-glucan phosphorylase 1782906..1785392 Thermosipho melanesiensis BI429 5297176 YP_001307019.1 CDS Tmel_1799 NC_009616.1 1785420 1786286 R TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; signal peptidase I complement(1785420..1786286) Thermosipho melanesiensis BI429 5297177 YP_001307020.1 CDS rplS NC_009616.1 1786292 1786639 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1786292..1786639) Thermosipho melanesiensis BI429 5296884 YP_001307021.1 CDS Tmel_1801 NC_009616.1 1786654 1787220 R hypothetical protein complement(1786654..1787220) Thermosipho melanesiensis BI429 5297029 YP_001307022.1 CDS trmD NC_009616.1 1787210 1787950 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1787210..1787950) Thermosipho melanesiensis BI429 5297030 YP_001307023.1 CDS Tmel_1803 NC_009616.1 1787947 1788483 R TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; 16S rRNA processing protein RimM complement(1787947..1788483) Thermosipho melanesiensis BI429 5297346 YP_001307024.1 CDS Tmel_1804 NC_009616.1 1788480 1788704 R RNA-binding protein complement(1788480..1788704) Thermosipho melanesiensis BI429 5297347 YP_001307025.1 CDS rpsP NC_009616.1 1788701 1788988 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1788701..1788988) Thermosipho melanesiensis BI429 5296537 YP_001307026.1 CDS Tmel_1806 NC_009616.1 1789010 1790317 R TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase; signal recognition particle protein complement(1789010..1790317) Thermosipho melanesiensis BI429 5296538 YP_001307027.1 CDS Tmel_1807 NC_009616.1 1790669 1791646 D TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein, family 1; ABC transporter periplasmic-binding protein 1790669..1791646 Thermosipho melanesiensis BI429 5296748 YP_001307028.1 CDS Tmel_1808 NC_009616.1 1791619 1793151 D PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component 1791619..1793151 Thermosipho melanesiensis BI429 5296749 YP_001307029.1 CDS Tmel_1809 NC_009616.1 1793148 1794014 R PFAM: Rubrerythrin; protein of unknown function DUF125, transmembrane; hypothetical protein complement(1793148..1794014) Thermosipho melanesiensis BI429 5296562 YP_001307030.1 CDS Tmel_1810 NC_009616.1 1794016 1794792 R PFAM: protein of unknown function DUF364; hypothetical protein complement(1794016..1794792) Thermosipho melanesiensis BI429 5296499 YP_001307031.1 CDS Tmel_1811 NC_009616.1 1794805 1795419 R Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites; N-glycosylase/DNA lyase complement(1794805..1795419) Thermosipho melanesiensis BI429 5296500 YP_001307032.1 CDS Tmel_1812 NC_009616.1 1795540 1796298 D response regulator receiver/SARP domain-containing protein 1795540..1796298 Thermosipho melanesiensis BI429 5297378 YP_001307033.1 CDS Tmel_1813 NC_009616.1 1796314 1797159 R hypothetical protein complement(1796314..1797159) Thermosipho melanesiensis BI429 5297379 YP_001307034.1 CDS Tmel_1814 NC_009616.1 1797206 1798144 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(1797206..1798144) Thermosipho melanesiensis BI429 5297270 YP_001307035.1 CDS Tmel_1815 NC_009616.1 1798187 1799521 R GTPase-like protein complement(1798187..1799521) Thermosipho melanesiensis BI429 5297271 YP_001307036.1 CDS Tmel_1816 NC_009616.1 1799741 1801285 R PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(1799741..1801285) Thermosipho melanesiensis BI429 5297463 YP_001307037.1 CDS Tmel_1817 NC_009616.1 1801310 1802650 R PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; metal dependent phosphohydrolase complement(1801310..1802650) Thermosipho melanesiensis BI429 5297464 YP_001307038.1 CDS Tmel_1818 NC_009616.1 1802793 1803632 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1802793..1803632) Thermosipho melanesiensis BI429 5296983 YP_001307039.1 CDS Tmel_1819 NC_009616.1 1803644 1804525 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1803644..1804525) Thermosipho melanesiensis BI429 5297465 YP_001307040.1 CDS Tmel_1820 NC_009616.1 1804569 1805804 R PFAM: extracellular solute-binding protein, family 1; extracellular solute-binding protein complement(1804569..1805804) Thermosipho melanesiensis BI429 5297466 YP_001307041.1 CDS Tmel_1821 NC_009616.1 1806136 1807347 D PFAM: glycosyl transferase, group 1; group 1 glycosyl transferase 1806136..1807347 Thermosipho melanesiensis BI429 5297844 YP_001307042.1 CDS Tmel_1822 NC_009616.1 1807505 1808461 D PFAM: ROK family protein; ROK family protein 1807505..1808461 Thermosipho melanesiensis BI429 5297845 YP_001307043.1 CDS Tmel_1823 NC_009616.1 1808445 1809404 R PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; histidine kinase complement(1808445..1809404) Thermosipho melanesiensis BI429 5297011 YP_001307044.1 CDS Tmel_1824 NC_009616.1 1809382 1810050 R PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator complement(1809382..1810050) Thermosipho melanesiensis BI429 5297012 YP_001307045.1 CDS Tmel_1825 NC_009616.1 1810047 1810697 R TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; phosphate uptake regulator PhoU complement(1810047..1810697) Thermosipho melanesiensis BI429 5296732 YP_001307046.1 CDS Tmel_1826 NC_009616.1 1810709 1811461 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein complement(1810709..1811461) Thermosipho melanesiensis BI429 5296733 YP_001307047.1 CDS Tmel_1827 NC_009616.1 1811458 1812270 R TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; phosphate ABC transporter inner membrane subunit PstA complement(1811458..1812270) Thermosipho melanesiensis BI429 5296898 YP_001307048.1 CDS Tmel_1828 NC_009616.1 1812263 1813120 R PFAM: binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport systems inner membrane component complement(1812263..1813120) Thermosipho melanesiensis BI429 5297928 YP_001307049.1 CDS Tmel_1829 NC_009616.1 1813132 1813953 R TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1; phosphate binding protein complement(1813132..1813953) Thermosipho melanesiensis BI429 5297929 YP_001307050.1 CDS Tmel_1830 NC_009616.1 1814069 1815394 R PFAM: aldehyde dehydrogenase; aldehyde dehydrogenase complement(1814069..1815394) Thermosipho melanesiensis BI429 5297364 YP_001307051.1 CDS Tmel_1831 NC_009616.1 1815366 1815920 R PFAM: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase complement(1815366..1815920) Thermosipho melanesiensis BI429 5297365 YP_001307052.1 CDS Tmel_1832 NC_009616.1 1816091 1816516 D PFAM: regulatory protein, MarR; MarR family transcriptional regulator 1816091..1816516 Thermosipho melanesiensis BI429 5297120 YP_001307053.1 CDS Tmel_1833 NC_009616.1 1816518 1817525 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; NAD-dependent epimerase/dehydratase 1816518..1817525 Thermosipho melanesiensis BI429 5297121 YP_001307054.1 CDS Tmel_1834 NC_009616.1 1817496 1818416 R PFAM: PfkB domain protein; ribokinase-like domain-containing protein complement(1817496..1818416) Thermosipho melanesiensis BI429 5297675 YP_001307055.1 CDS Tmel_1835 NC_009616.1 1818456 1819190 R TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; 3-oxoacyl-(acyl-carrier-protein) reductase complement(1818456..1819190) Thermosipho melanesiensis BI429 5297676 YP_001307056.1 CDS Tmel_1836 NC_009616.1 1819254 1819988 R PFAM: cobalt transport protein; cobalt transport protein complement(1819254..1819988) Thermosipho melanesiensis BI429 5297064 YP_001307057.1 CDS hppA NC_009616.1 1820001 1822139 R pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase complement(1820001..1822139) Thermosipho melanesiensis BI429 5297539 YP_001307058.1 CDS Tmel_1838 NC_009616.1 1822288 1823007 D PFAM: response regulator receiver; transcriptional regulator domain protein; two component transcriptional regulator 1822288..1823007 Thermosipho melanesiensis BI429 5297540 YP_001307059.1 CDS Tmel_1839 NC_009616.1 1823011 1824282 D TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; PAS/PAC sensor signal transduction histidine kinase 1823011..1824282 Thermosipho melanesiensis BI429 5296773 YP_001307060.1 CDS Tmel_1840 NC_009616.1 1824269 1825573 D TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal domain; pyrimidine-nucleoside phosphorylase 1824269..1825573 Thermosipho melanesiensis BI429 5296774 YP_001307061.1 CDS Tmel_1841 NC_009616.1 1825583 1827187 D hypothetical protein 1825583..1827187 Thermosipho melanesiensis BI429 5296635 YP_001307062.1 CDS Tmel_1842 NC_009616.1 1827190 1827717 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1827190..1827717 Thermosipho melanesiensis BI429 5296636 YP_001307063.1 CDS Tmel_1843 NC_009616.1 1827731 1829083 D catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate isomerase 1827731..1829083 Thermosipho melanesiensis BI429 5297905 YP_001307064.1 CDS Tmel_1844 NC_009616.1 1829083 1829298 D hypothetical protein 1829083..1829298 Thermosipho melanesiensis BI429 5297906 YP_001307065.1 CDS Tmel_1845 NC_009616.1 1829295 1829831 D TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; dephospho-CoA kinase 1829295..1829831 Thermosipho melanesiensis BI429 5297127 YP_001307066.1 CDS Tmel_1846 NC_009616.1 1829847 1830659 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; diguanylate cyclase complement(1829847..1830659) Thermosipho melanesiensis BI429 5297730 YP_001307067.1 CDS Tmel_1847 NC_009616.1 1830699 1832687 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1830699..1832687) Thermosipho melanesiensis BI429 5297731 YP_001307068.1 CDS Tmel_1848 NC_009616.1 1832677 1834281 R PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; fibronectin-binding A domain-containing protein complement(1832677..1834281) Thermosipho melanesiensis BI429 5297873 YP_001307069.1 CDS Tmel_1849 NC_009616.1 1834363 1836207 R PFAM: extracellular solute-binding protein, family 5; extracellular solute-binding protein complement(1834363..1836207) Thermosipho melanesiensis BI429 5297874 YP_001307070.1 CDS Tmel_1850 NC_009616.1 1836312 1836806 R hypothetical protein complement(1836312..1836806) Thermosipho melanesiensis BI429 5297627 YP_001307071.1 CDS Tmel_1851 NC_009616.1 1836824 1837105 R hypothetical protein complement(1836824..1837105) Thermosipho melanesiensis BI429 5297628 YP_001307072.1 CDS Tmel_1852 NC_009616.1 1837122 1837364 R hypothetical protein complement(1837122..1837364) Thermosipho melanesiensis BI429 5296962 YP_001307073.1 CDS Tmel_1853 NC_009616.1 1837562 1838008 D hypothetical protein 1837562..1838008 Thermosipho melanesiensis BI429 5296930 YP_001307074.1 CDS Tmel_1854 NC_009616.1 1838005 1839282 D PFAM: protein of unknown function DUF795; hypothetical protein 1838005..1839282 Thermosipho melanesiensis BI429 5296656 YP_001307075.1 CDS Tmel_1855 NC_009616.1 1839275 1841980 D PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; DEAD/DEAH box helicase domain-containing protein 1839275..1841980 Thermosipho melanesiensis BI429 5297528 YP_001307076.1 CDS Tmel_1857 NC_009616.1 1842742 1843830 R non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA complement(1842742..1843830) Thermosipho melanesiensis BI429 5297124 YP_001307077.1 CDS Tmel_1858 NC_009616.1 1843901 1844464 R with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT complement(1843901..1844464) Thermosipho melanesiensis BI429 5297916 YP_001307078.1 CDS Tmel_1859 NC_009616.1 1844466 1845344 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(1844466..1845344) Thermosipho melanesiensis BI429 5297917 YP_001307079.1 CDS Tmel_1860 NC_009616.1 1845359 1847038 R TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; methylmalonyl-CoA mutase, large subunit complement(1845359..1847038) Thermosipho melanesiensis BI429 5297983 YP_001307080.1 CDS Tmel_1861 NC_009616.1 1847073 1847711 R PFAM: class II aldolase/adducin family protein; class II aldolase/adducin family protein complement(1847073..1847711) Thermosipho melanesiensis BI429 5297984 YP_001307081.1 CDS Tmel_1862 NC_009616.1 1847708 1848010 R hypothetical protein complement(1847708..1848010) Thermosipho melanesiensis BI429 5297174 YP_001307082.1 CDS Tmel_1863 NC_009616.1 1847992 1848804 R TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; holo-acyl-carrier-protein synthase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; 4'-phosphopantetheinyl transferase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(1847992..1848804) Thermosipho melanesiensis BI429 5297175 YP_001307083.1 CDS Tmel_1864 NC_009616.1 1848801 1850177 R catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase complement(1848801..1850177) Thermosipho melanesiensis BI429 5297343 YP_001307084.1 CDS infB NC_009616.1 1850182 1852260 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1850182..1852260) Thermosipho melanesiensis BI429 5297139 YP_001307085.1 CDS Tmel_1866 NC_009616.1 1852282 1852482 R hypothetical protein complement(1852282..1852482) Thermosipho melanesiensis BI429 5297140 YP_001307086.1 CDS Tmel_1867 NC_009616.1 1852504 1853343 R PFAM: chemotaxis sensory transducer; methyl-accepting chemotaxis sensory transducer complement(1852504..1853343) Thermosipho melanesiensis BI429 5296685 YP_001307087.1 CDS Tmel_1868 NC_009616.1 1853349 1854113 R PFAM: beta-lactamase domain protein; beta-lactamase domain-containing protein complement(1853349..1854113) Thermosipho melanesiensis BI429 5296686 YP_001307088.1 CDS Tmel_1869 NC_009616.1 1854282 1854911 D TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; hypothetical protein 1854282..1854911 Thermosipho melanesiensis BI429 5297414 YP_001307089.1 CDS Tmel_1870 NC_009616.1 1855236 1856252 D PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; succinate--CoA ligase 1855236..1856252 Thermosipho melanesiensis BI429 5297415 YP_001307090.1 CDS Tmel_1871 NC_009616.1 1856249 1857091 D PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; CoA-binding domain-containing protein 1856249..1857091 Thermosipho melanesiensis BI429 5296629 YP_001307091.1 CDS Tmel_1872 NC_009616.1 1857095 1858225 D TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; YidE/YbjL duplication 1857095..1858225 Thermosipho melanesiensis BI429 5296630 YP_001307092.1 CDS Tmel_1873 NC_009616.1 1858515 1859477 D TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; aspartate-semialdehyde dehydrogenase 1858515..1859477 Thermosipho melanesiensis BI429 5296809 YP_001307093.1 CDS Tmel_1874 NC_009616.1 1859470 1860168 D PFAM: diaminopimelate epimerase; diaminopimelate epimerase 1859470..1860168 Thermosipho melanesiensis BI429 5297262 YP_001307094.1 CDS Tmel_1875 NC_009616.1 1860161 1861027 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1860161..1861027 Thermosipho melanesiensis BI429 5297263 YP_001307095.1 CDS Tmel_1876 NC_009616.1 1861024 1861677 D PFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 1861024..1861677 Thermosipho melanesiensis BI429 5297475 YP_001307096.1 CDS Tmel_1877 NC_009616.1 1861674 1862369 D PFAM: transferase hexapeptide repeat containing protein; Tetrahydrodipicolinate succinyltransferase N-terminal domain protein; tetrahydrodipicolinate succinyltransferase domain-containing protein 1861674..1862369 Thermosipho melanesiensis BI429 5297476 YP_001307097.1 CDS Tmel_1878 NC_009616.1 1862384 1863583 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1862384..1863583 Thermosipho melanesiensis BI429 5297914 YP_001307098.1 CDS Tmel_1879 NC_009616.1 1863588 1864724 D PFAM: aminotransferase class-III; class III aminotransferase 1863588..1864724 Thermosipho melanesiensis BI429 5297915 YP_001307099.1 CDS Tmel_1881 NC_009616.1 1865880 1866995 D PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; DegT/DnrJ/EryC1/StrS aminotransferase 1865880..1866995 Thermosipho melanesiensis BI429 5296885 YP_001307100.1 CDS Tmel_1882 NC_009616.1 1867008 1868474 D TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 1867008..1868474 Thermosipho melanesiensis BI429 5297407 YP_001307101.1 CDS Tmel_1883 NC_009616.1 1868471 1869769 D nicotinic acid phosphoribosyltransferase-like protein 1868471..1869769 Thermosipho melanesiensis BI429 5297405 YP_001307102.1 CDS Tmel_1884 NC_009616.1 1869872 1870081 D hypothetical protein 1869872..1870081 Thermosipho melanesiensis BI429 5297570 YP_001307103.1 CDS gcvT NC_009616.1 1870096 1871187 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1870096..1871187 Thermosipho melanesiensis BI429 5297571 YP_001307104.1 CDS Tmel_1886 NC_009616.1 1871193 1872512 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1871193..1872512 Thermosipho melanesiensis BI429 5297774 YP_001307105.1 CDS Tmel_1887 NC_009616.1 1872528 1873973 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1872528..1873973 Thermosipho melanesiensis BI429 5297775 YP_001307106.1 CDS Tmel_1888 NC_009616.1 1873975 1875060 D PFAM: iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 1873975..1875060 Thermosipho melanesiensis BI429 5296756 YP_001307107.1 CDS Tmel_1889 NC_009616.1 1875057 1876223 D PFAM: conserved hypothetical protein 95; SMART: PUA domain containing protein; hypothetical protein 1875057..1876223 Thermosipho melanesiensis BI429 5296757 YP_001307108.1 CDS Tmel_1890 NC_009616.1 1876228 1877886 D SMART: Pyrrolo-quinoline quinone; Pyrrolo-quinoline quinone 1876228..1877886 Thermosipho melanesiensis BI429 5297663 YP_001307109.1 CDS Tmel_1891 NC_009616.1 1877888 1878427 D PFAM: NUDIX hydrolase; NUDIX hydrolase 1877888..1878427 Thermosipho melanesiensis BI429 5297664 YP_001307110.1 CDS Tmel_1892 NC_009616.1 1878424 1879647 D catalyzes the transamination of diaminopimelate with 2-oxoglutarate to produce tetrahydrodipicolinate and glutamate; diaminopimelate aminotransferase 1878424..1879647 Thermosipho melanesiensis BI429 5297210 YP_001307111.1 CDS Tmel_1893 NC_009616.1 1879666 1881318 D catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1879666..1881318 Thermosipho melanesiensis BI429 5297708 YP_001307112.1 CDS Tmel_1895 NC_009616.1 1882190 1882492 R PFAM: transposase IS3/IS911 family protein; transposase IS3/IS911 family protein complement(1882190..1882492) Thermosipho melanesiensis BI429 5297387 YP_001307113.1 CDS Tmel_1896 NC_009616.1 1882588 1883748 R PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha complement(1882588..1883748) Thermosipho melanesiensis BI429 5297471 YP_001307114.1 CDS Tmel_1897 NC_009616.1 1883741 1883968 R PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(1883741..1883968) Thermosipho melanesiensis BI429 5297472 YP_001307115.1 CDS Tmel_1898 NC_009616.1 1883983 1885119 R TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; sodium ion-translocating decarboxylase subunit beta complement(1883983..1885119) Thermosipho melanesiensis BI429 5297765 YP_001307116.1 CDS Tmel_1899 NC_009616.1 1885214 1885996 R DNA polymerase III gamma/tau subunits-like protein complement(1885214..1885996) Thermosipho melanesiensis BI429 5297766 YP_001307117.1 CDS Tmel_1900 NC_009616.1 1885989 1886621 R PFAM: ABC transporter related; SMART: AAA ATPase; ABC transporter-like protein complement(1885989..1886621) Thermosipho melanesiensis BI429 5297389 YP_001307118.1 CDS Tmel_1901 NC_009616.1 1886663 1887421 R PFAM: protein of unknown function DUF62; hypothetical protein complement(1886663..1887421) Thermosipho melanesiensis BI429 5297390 YP_001307119.1 CDS Tmel_1902 NC_009616.1 1887431 1888438 R PFAM: phosphofructokinase; 6-phosphofructokinase complement(1887431..1888438) Thermosipho melanesiensis BI429 5297412 YP_001307120.1 CDS hppA NC_009616.1 1888440 1890389 R pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase complement(1888440..1890389) Thermosipho melanesiensis BI429 5297899 YP_001307121.1 CDS Tmel_1904 NC_009616.1 1890435 1891343 R TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein; protein-export membrane protein SecF complement(1890435..1891343) Thermosipho melanesiensis BI429 5297900 YP_001307122.1 CDS Tmel_1905 NC_009616.1 1891340 1892773 R TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; protein-export membrane protein SecD complement(1891340..1892773) Thermosipho melanesiensis BI429 5297537 YP_001307123.1 CDS Tmel_1906 NC_009616.1 1892792 1893142 R TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; preprotein translocase subunit YajC complement(1892792..1893142) Thermosipho melanesiensis BI429 5297538 YP_001307124.1 CDS Tmel_1907 NC_009616.1 1893161 1893976 R PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase; tetrahydrofolate dehydrogenase/cyclohydrolase complement(1893161..1893976) Thermosipho melanesiensis BI429 5297046 YP_001307125.1 CDS Tmel_1908 NC_009616.1 1893989 1894339 R hypothetical protein complement(1893989..1894339) Thermosipho melanesiensis BI429 5297047 YP_001307126.1 CDS thyX NC_009616.1 1894336 1895025 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(1894336..1895025) Thermosipho melanesiensis BI429 5297546 YP_001307127.1 CDS rnhB NC_009616.1 1895015 1895665 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1895015..1895665) Thermosipho melanesiensis BI429 5297547 YP_001307128.1 CDS Tmel_1911 NC_009616.1 1895662 1896138 R hypothetical protein complement(1895662..1896138) Thermosipho melanesiensis BI429 5297545 YP_001307129.1 CDS Tmel_1912 NC_009616.1 1896149 1897096 R hypothetical protein complement(1896149..1897096) Thermosipho melanesiensis BI429 5297897 YP_001307130.1 CDS Tmel_1913 NC_009616.1 1897117 1897821 R PFAM: Silent information regulator protein Sir2; silent information regulator protein Sir2 complement(1897117..1897821) Thermosipho melanesiensis BI429 5297898 YP_001307131.1 CDS Tmel_1914 NC_009616.1 1897784 1898326 R PFAM: Chromate transporter; chromate transporter complement(1897784..1898326) Thermosipho melanesiensis BI429 5297665 YP_001307132.1 CDS Tmel_1915 NC_009616.1 1898307 1898543 R hypothetical protein complement(1898307..1898543) Thermosipho melanesiensis BI429 5297666 YP_001307133.1 CDS Tmel_1916 NC_009616.1 1898548 1899984 R PFAM: Exonuclease VII, large subunit; exodeoxyribonuclease VII complement(1898548..1899984) Thermosipho melanesiensis BI429 5297360 YP_001307134.1 CDS Tmel_1917 NC_009616.1 1899984 1902656 R TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; DNA polymerase I complement(1899984..1902656) Thermosipho melanesiensis BI429 5297361 YP_001307135.1 CDS Tmel_1918 NC_009616.1 1902634 1902999 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; alkylhydroperoxidase complement(1902634..1902999) Thermosipho melanesiensis BI429 5297032 YP_001307136.1 CDS Tmel_1919 NC_009616.1 1903001 1905088 R PFAM: cell division protein FtsA; cell division protein FtsA complement(1903001..1905088) Thermosipho melanesiensis BI429 5297033 YP_001307137.1 CDS Tmel_1920 NC_009616.1 1905092 1907374 R TIGRFAM: MutS2 family protein; PFAM: DNA mismatch repair protein MutS domain protein; Smr protein/MutS2; SMART: AAA ATPase; MutS III domain protein; MutS2 family protein complement(1905092..1907374) Thermosipho melanesiensis BI429 5297504 YP_001307138.1 CDS Tmel_1921 NC_009616.1 1907386 1908024 R hypothetical protein complement(1907386..1908024) Thermosipho melanesiensis BI429 5297920 YP_001307139.1 CDS Tmel_1922 NC_009616.1 1908074 1909267 R PFAM: phosphate transporter; phosphate transporter complement(1908074..1909267) Thermosipho melanesiensis BI429 5297921 YP_001307140.1 CDS Tmel_1923 NC_009616.1 1909285 1909956 R PFAM: protein of unknown function DUF47; hypothetical protein complement(1909285..1909956) Thermosipho melanesiensis BI429 5297945 YP_001307141.1 CDS Tmel_1924 NC_009616.1 1909958 1910929 R PFAM: conserved hypothetical protein 374; hypothetical protein complement(1909958..1910929) Thermosipho melanesiensis BI429 5297946 YP_001307142.1 CDS Tmel_1925 NC_009616.1 1910913 1911596 R PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase complement(1910913..1911596) Thermosipho melanesiensis BI429 5297656 YP_001307143.1 CDS Tmel_1926 NC_009616.1 1911606 1912463 R PFAM: helix-turn-helix, Fis-type; Fis family transcriptional regulator complement(1911606..1912463) Thermosipho melanesiensis BI429 5297657 YP_001307144.1 CDS Tmel_1927 NC_009616.1 1912468 1913406 R this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable reaction at the extreme temperatures these organisms live under; carbamate kinase-like carbamoyl phosphate synthetase complement(1912468..1913406) Thermosipho melanesiensis BI429 5297842 YP_001307145.1 CDS Tmel_1928 NC_009616.1 1913403 1914305 R PFAM: phosphate acetyl/butaryl transferase; phosphate butyryltransferase complement(1913403..1914305) Thermosipho melanesiensis BI429 5297843 YP_001307146.1 CDS Tmel_1929 NC_009616.1 1914310 1915128 R PFAM: peptidase M55, D-aminopeptidase; peptidase M55, D-aminopeptidase complement(1914310..1915128) Thermosipho melanesiensis BI429 5298459 Tmel_R0001 tRNA Tmel_R0001 NC_009616.1 22289 22366 R tRNA-Asp complement(22289..22366) Thermosipho melanesiensis BI429 5297269 Tmel_R0002 tRNA Tmel_R0002 NC_009616.1 22438 22515 R tRNA-Asp complement(22438..22515) Thermosipho melanesiensis BI429 5298454 Tmel_R0004 tRNA Tmel_R0004 NC_009616.1 45538 45625 R tRNA-Leu complement(45538..45625) Thermosipho melanesiensis BI429 5298331 Tmel_R0005 tRNA Tmel_R0005 NC_009616.1 57799 57874 R tRNA-Ala complement(57799..57874) Thermosipho melanesiensis BI429 5297757 Tmel_R0006 tRNA Tmel_R0006 NC_009616.1 119307 119382 R tRNA-Ala complement(119307..119382) Thermosipho melanesiensis BI429 5297204 Tmel_R0007 tRNA Tmel_R0007 NC_009616.1 125711 125787 D tRNA-Pro 125711..125787 Thermosipho melanesiensis BI429 5297848 Tmel_R0008 tRNA Tmel_R0008 NC_009616.1 125791 125866 D tRNA-Gly 125791..125866 Thermosipho melanesiensis BI429 5298136 Tmel_R0009 tRNA Tmel_R0009 NC_009616.1 125884 125960 D tRNA-Arg 125884..125960 Thermosipho melanesiensis BI429 5298372 Tmel_R0010 tRNA Tmel_R0010 NC_009616.1 125984 126059 D tRNA-His 125984..126059 Thermosipho melanesiensis BI429 5298406 Tmel_R0011 tRNA Tmel_R0011 NC_009616.1 126093 126169 D tRNA-Arg 126093..126169 Thermosipho melanesiensis BI429 5298045 Tmel_R0012 tRNA Tmel_R0012 NC_009616.1 208635 208711 R tRNA-Met complement(208635..208711) Thermosipho melanesiensis BI429 5298266 Tmel_R0013 tRNA Tmel_R0013 NC_009616.1 208742 208831 R tRNA-Leu complement(208742..208831) Thermosipho melanesiensis BI429 5298416 Tmel_R0017 tRNA Tmel_R0017 NC_009616.1 304049 304125 R tRNA-Arg complement(304049..304125) Thermosipho melanesiensis BI429 5296890 Tmel_R0018 tRNA Tmel_R0018 NC_009616.1 343693 343766 R tRNA-Gln complement(343693..343766) Thermosipho melanesiensis BI429 5296689 Tmel_R0022 tRNA Tmel_R0022 NC_009616.1 357666 357741 R tRNA-Met complement(357666..357741) Thermosipho melanesiensis BI429 5298011 Tmel_R0023 tRNA Tmel_R0023 NC_009616.1 371105 371180 D tRNA-Asn 371105..371180 Thermosipho melanesiensis BI429 5296659 Tmel_R0024 tRNA Tmel_R0024 NC_009616.1 387866 387941 D tRNA-Thr 387866..387941 Thermosipho melanesiensis BI429 5297846 Tmel_R0025 tRNA Tmel_R0025 NC_009616.1 405423 405498 D tRNA-Asn 405423..405498 Thermosipho melanesiensis BI429 5297622 Tmel_R0026 tRNA Tmel_R0026 NC_009616.1 588725 588810 D tRNA-Ser 588725..588810 Thermosipho melanesiensis BI429 5297495 Tmel_R0029 tRNA Tmel_R0029 NC_009616.1 640199 640274 R tRNA-Ala complement(640199..640274) Thermosipho melanesiensis BI429 5298287 Tmel_R0030 tRNA Tmel_R0030 NC_009616.1 640279 640355 R tRNA-Ile complement(640279..640355) Thermosipho melanesiensis BI429 5298303 Tmel_R0034 tRNA Tmel_R0034 NC_009616.1 645243 645318 R tRNA-Ala complement(645243..645318) Thermosipho melanesiensis BI429 5298025 Tmel_R0035 tRNA Tmel_R0035 NC_009616.1 645323 645399 R tRNA-Ile complement(645323..645399) Thermosipho melanesiensis BI429 5297985 Tmel_R0037 tRNA Tmel_R0037 NC_009616.1 654791 654867 R tRNA-Arg complement(654791..654867) Thermosipho melanesiensis BI429 5297202 Tmel_R0038 tRNA Tmel_R0038 NC_009616.1 654904 654993 R tRNA-Ser complement(654904..654993) Thermosipho melanesiensis BI429 5298352 Tmel_R0039 tRNA Tmel_R0039 NC_009616.1 665819 665907 R tRNA-Leu complement(665819..665907) Thermosipho melanesiensis BI429 5297312 Tmel_R0040 tRNA Tmel_R0040 NC_009616.1 677738 677814 D tRNA-Cys 677738..677814 Thermosipho melanesiensis BI429 5297154 Tmel_R0041 tRNA Tmel_R0041 NC_009616.1 677823 677898 D tRNA-Met 677823..677898 Thermosipho melanesiensis BI429 5298232 Tmel_R0042 tRNA Tmel_R0042 NC_009616.1 679035 679110 D tRNA-Thr 679035..679110 Thermosipho melanesiensis BI429 5297762 Tmel_R0043 tRNA Tmel_R0043 NC_009616.1 679120 679206 D tRNA-Tyr 679120..679206 Thermosipho melanesiensis BI429 5298042 Tmel_R0044 tRNA Tmel_R0044 NC_009616.1 679392 679467 D tRNA-Trp 679392..679467 Thermosipho melanesiensis BI429 5297351 Tmel_R0045 tRNA Tmel_R0045 NC_009616.1 682872 682946 R tRNA-Gly complement(682872..682946) Thermosipho melanesiensis BI429 5297353 Tmel_R0046 tRNA Tmel_R0046 NC_009616.1 682957 683043 R tRNA-Leu complement(682957..683043) Thermosipho melanesiensis BI429 5298419 Tmel_R0047 tRNA Tmel_R0047 NC_009616.1 683049 683124 R tRNA-Lys complement(683049..683124) Thermosipho melanesiensis BI429 5298265 Tmel_R0048 tRNA Tmel_R0048 NC_009616.1 891345 891421 D tRNA-Pro 891345..891421 Thermosipho melanesiensis BI429 5298048 Tmel_R0049 tRNA Tmel_R0049 NC_009616.1 913591 913667 R tRNA-Thr complement(913591..913667) Thermosipho melanesiensis BI429 5298176 Tmel_R0050 tRNA Tmel_R0050 NC_009616.1 961018 961092 D tRNA-Glu 961018..961092 Thermosipho melanesiensis BI429 5297702 Tmel_R0051 tRNA Tmel_R0051 NC_009616.1 961096 961170 D tRNA-Arg 961096..961170 Thermosipho melanesiensis BI429 5298330 Tmel_R0052 tRNA Tmel_R0052 NC_009616.1 961178 961253 D tRNA-Lys 961178..961253 Thermosipho melanesiensis BI429 5298320 Tmel_R0053 tRNA Tmel_R0053 NC_009616.1 983707 983781 D tRNA-Val 983707..983781 Thermosipho melanesiensis BI429 5297221 Tmel_R0054 tRNA Tmel_R0054 NC_009616.1 983796 983870 D tRNA-Gln 983796..983870 Thermosipho melanesiensis BI429 5297752 Tmel_R0055 tRNA Tmel_R0055 NC_009616.1 1257290 1257366 D tRNA-Pro 1257290..1257366 Thermosipho melanesiensis BI429 5297132 Tmel_R0057 tRNA Tmel_R0057 NC_009616.1 1342233 1342319 D tRNA-Leu 1342233..1342319 Thermosipho melanesiensis BI429 5297892 Tmel_R0059 tRNA Tmel_R0059 NC_009616.1 1393329 1393416 R tRNA-Ser complement(1393329..1393416) Thermosipho melanesiensis BI429 5298208 Tmel_R0060 tRNA Tmel_R0060 NC_009616.1 1415230 1415320 R tRNA-Ser complement(1415230..1415320) Thermosipho melanesiensis BI429 5298185 Tmel_R0061 tRNA Tmel_R0061 NC_009616.1 1436794 1436869 D tRNA-Glu 1436794..1436869 Thermosipho melanesiensis BI429 5296844 Tmel_R0062 tRNA Tmel_R0062 NC_009616.1 1436875 1436949 D tRNA-Val 1436875..1436949 Thermosipho melanesiensis BI429 5297925 Tmel_R0063 tRNA Tmel_R0063 NC_009616.1 1436964 1437039 D tRNA-Phe 1436964..1437039 Thermosipho melanesiensis BI429 5297650 Tmel_R0064 tRNA Tmel_R0064 NC_009616.1 1562595 1562670 D tRNA-Gly 1562595..1562670 Thermosipho melanesiensis BI429 5297483 Tmel_R0065 tRNA Tmel_R0065 NC_009616.1 1837436 1837510 D tRNA-Val 1837436..1837510 Thermosipho melanesiensis BI429 5296963 Tmel_R0014 rRNA Tmel_R0014 NC_009616.1 272808 272923 R 5S ribosomal RNA complement(272808..272923) Thermosipho melanesiensis BI429 5296556 Tmel_R0015 rRNA Tmel_R0015 NC_009616.1 272962 275901 R 23S ribosomal RNA complement(272962..275901) Thermosipho melanesiensis BI429 5298413 Tmel_R0016 rRNA Tmel_R0016 NC_009616.1 275980 277338 R 16S ribosomal RNA complement(275980..277338) Thermosipho melanesiensis BI429 5298397 Tmel_R0019 rRNA Tmel_R0019 NC_009616.1 352505 352620 R 5S ribosomal RNA complement(352505..352620) Thermosipho melanesiensis BI429 5296699 Tmel_R0020 rRNA Tmel_R0020 NC_009616.1 352659 355598 R 23S ribosomal RNA complement(352659..355598) Thermosipho melanesiensis BI429 5298065 Tmel_R0021 rRNA Tmel_R0021 NC_009616.1 355677 357035 R 16S ribosomal RNA complement(355677..357035) Thermosipho melanesiensis BI429 5298225 Tmel_R0027 rRNA Tmel_R0027 NC_009616.1 637065 637180 R 5S ribosomal RNA complement(637065..637180) Thermosipho melanesiensis BI429 5297488 Tmel_R0028 rRNA Tmel_R0028 NC_009616.1 637219 640158 R 23S ribosomal RNA complement(637219..640158) Thermosipho melanesiensis BI429 5298270 Tmel_R0031 rRNA Tmel_R0031 NC_009616.1 640404 641762 R 16S ribosomal RNA complement(640404..641762) Thermosipho melanesiensis BI429 5298346 Tmel_R0032 rRNA Tmel_R0032 NC_009616.1 642109 642224 R 5S ribosomal RNA complement(642109..642224) Thermosipho melanesiensis BI429 5298411 Tmel_R0033 rRNA Tmel_R0033 NC_009616.1 642263 645202 R 23S ribosomal RNA complement(642263..645202) Thermosipho melanesiensis BI429 5298444 Tmel_R0036 rRNA Tmel_R0036 NC_009616.1 645448 646806 R 16S ribosomal RNA complement(645448..646806) Thermosipho melanesiensis BI429 5298023