-- dump date 20111121_015500 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_004438592.1 332296670 10581126 52..1593 1 NC_015500.1 COGs: COG0593 ATPase involved in DNA replication initiation; HAMAP: Chromosomal replication control, initiator DnaA; InterPro IPR003593:IPR013159:IPR013317:IPR001957; KEGG: ssm:Spirs_0001 chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication control, initiator (DnaA)/regulator (Hda); Chromosomal replication initiator, DnaA C-terminal; SMART: Chromosomal replication initiator, DnaA C-terminal; ATPase, AAA+ type, core; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: Chromosomal replication control, initiator DnaA; IMG reference gene:2504918866; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA; chromosomal replication initiator protein dnaA 1593 10581126 Trebr_0001 Treponema brennaborense DSM 12168 chromosomal replication initiator protein dnaA YP_004438592.1 52 D 906968 CDS YP_004438593.1 332296671 10578479 1841..2944 1 NC_015500.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: tde:TDE0231 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain; IMG reference gene:2504918867; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit; DNA polymerase III subunit beta 2944 10578479 Trebr_0002 Treponema brennaborense DSM 12168 DNA polymerase III subunit beta YP_004438593.1 1841 D 906968 CDS YP_004438594.1 332296672 10578480 2954..4042 1 NC_015500.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); HAMAP: DNA replication and repair protein recF; InterPro IPR003395:IPR001238; KEGG: tpp:TPASS_0003 recombination protein RecF; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA-binding, RecF; IMG reference gene:2504918868; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein; DNA replication and repair protein RecF 4042 10578480 Trebr_0003 Treponema brennaborense DSM 12168 DNA replication and repair protein RecF YP_004438594.1 2954 D 906968 CDS YP_004438595.1 332296673 10578481 4035..4562 1 NC_015500.1 InterPro IPR007922; KEGG: ssm:Spirs_0005 protein of unknown function DUF721; PFAM: Protein of unknown function DUF721; SPTR: uncharacterized protein; IMG reference gene:2504918869; PFAM: Protein of unknown function (DUF721); hypothetical protein 4562 10578481 Trebr_0004 Treponema brennaborense DSM 12168 hypothetical protein YP_004438595.1 4035 D 906968 CDS YP_004438596.1 332296674 10578482 4651..4806 1 NC_015500.1 HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: sta:STHERM_c00060 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34; IMG reference gene:2504918870; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; 50S ribosomal protein L34 4806 10578482 Trebr_0005 Treponema brennaborense DSM 12168 50S ribosomal protein L34 YP_004438596.1 4651 D 906968 CDS YP_004438597.1 332296675 10578483 4826..5188 1 NC_015500.1 COGs: COG0594 RNase P protein component; HAMAP: Ribonuclease P; InterPro IPR000100; KEGG: ssm:Spirs_0007 ribonuclease P protein component; PFAM: Ribonuclease P; SPTR: Ribonuclease P protein component; TIGRFAM: Ribonuclease P; IMG reference gene:2504918871; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial; Ribonuclease P protein component 5188 10578483 Trebr_0006 Treponema brennaborense DSM 12168 Ribonuclease P protein component YP_004438597.1 4826 D 906968 CDS YP_004438598.1 332296676 10578484 5185..5406 1 NC_015500.1 COGs: COG0759 conserved hypothetical protein; HAMAP: Protein of unknown function DUF37; InterPro IPR002696; KEGG: hna:Hneap_2412 protein of unknown function DUF37; PFAM: Protein of unknown function DUF37; SPTR: UPF0161 protein Hneap_2412; TIGRFAM: Protein of unknown function DUF37; manually curated; IMG reference gene:2504918872; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD; hypothetical protein 5406 10578484 Trebr_0007 Treponema brennaborense DSM 12168 hypothetical protein YP_004438598.1 5185 D 906968 CDS YP_004438599.1 332296677 10578485 5446..7257 1 NC_015500.1 COGs: COG0706 Preprotein translocase subunit YidC; HAMAP: Membrane protein oxaA; InterPro IPR001708:IPR019998:IPR020001; KEGG: tde:TDE2396 inner membrane protein translocase component YidC; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Membrane protein oxaA; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; Membrane insertion protein, OxoA/YidC, N-terminal; IMG reference gene:2504918873; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain; membrane protein OxaA 7257 10578485 Trebr_0008 Treponema brennaborense DSM 12168 membrane protein OxaA YP_004438599.1 5446 D 906968 CDS YP_004438600.1 332296678 10578486 7297..7998 1 NC_015500.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ssm:Spirs_0009 single-stranded nucleic acid binding R3H domain protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Protein jag; IMG reference gene:2504918874; PFAM: R3H domain; single-stranded nucleic acid binding R3H domain-containing protein 7998 10578486 Trebr_0009 Treponema brennaborense DSM 12168 single-stranded nucleic acid binding R3H domain-containing protein YP_004438600.1 7297 D 906968 CDS YP_004438601.1 332296679 10578487 7998..8948 1 NC_015500.1 KEGG: tde:TDE2392 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918875; hypothetical protein 8948 10578487 Trebr_0010 Treponema brennaborense DSM 12168 hypothetical protein YP_004438601.1 7998 D 906968 CDS YP_004438602.1 332296680 10578488 8945..9973 1 NC_015500.1 COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130:IPR001179; KEGG: tde:TDE2391 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504918876; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; cyclophilin type peptidyl-prolyl cis-trans isomerase 9973 10578488 Trebr_0011 Treponema brennaborense DSM 12168 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_004438602.1 8945 D 906968 CDS YP_004438603.1 332296681 10578489 10081..10638 1 NC_015500.1 IMG reference gene:2504918877; hypothetical protein 10638 10578489 Trebr_0012 Treponema brennaborense DSM 12168 hypothetical protein YP_004438603.1 10081 D 906968 CDS YP_004438604.1 332296682 10578490 10647..12137 1 NC_015500.1 IMG reference gene:2504918878; hypothetical protein 12137 10578490 Trebr_0013 Treponema brennaborense DSM 12168 hypothetical protein YP_004438604.1 10647 D 906968 CDS YP_004438605.1 332296683 10578491 12321..13394 1 NC_015500.1 IMG reference gene:2504918879; PFAM: NlpC/P60 family; hypothetical protein 13394 10578491 Trebr_0014 Treponema brennaborense DSM 12168 hypothetical protein YP_004438605.1 12321 D 906968 CDS YP_004438606.1 332296684 10578492 13391..14596 1 NC_015500.1 KEGG: sta:STHERM_c19940 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918880; hypothetical protein 14596 10578492 Trebr_0015 Treponema brennaborense DSM 12168 hypothetical protein YP_004438606.1 13391 D 906968 CDS YP_004438607.1 332296685 10578493 14943..16370 1 NC_015500.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE1992 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA family protein; IMG reference gene:2504918881; PFAM: OmpA family; OmpA/MotB domain-containing protein 16370 10578493 Trebr_0016 Treponema brennaborense DSM 12168 OmpA/MotB domain-containing protein YP_004438607.1 14943 D 906968 CDS YP_004438608.1 332296686 10578494 complement(16633..18039) 1 NC_015500.1 COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: brm:Bmur_2037 glucuronate isomerase; PFAM: Uronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Uronate isomerase; IMG reference gene:2504918882; PFAM: Glucuronate isomerase; uronate isomerase 18039 10578494 Trebr_0017 Treponema brennaborense DSM 12168 uronate isomerase YP_004438608.1 16633 R 906968 CDS YP_004438609.1 332296687 10578495 complement(18036..19607) 1 NC_015500.1 COGs: COG2721 Altronate dehydratase; InterPro IPR013974:IPR007392; KEGG: csh:Closa_1093 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; SAF domain; PRIAM: Altronate dehydratase; SPTR: D-galactarate dehydratase; IMG reference gene:2504918883; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus; SAF domain; altronate dehydratase 19607 10578495 Trebr_0018 Treponema brennaborense DSM 12168 altronate dehydratase YP_004438609.1 18036 R 906968 CDS YP_004438610.1 332296688 10578496 complement(19638..21116) 1 NC_015500.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: cbe:Cbei_1838 altronate oxidoreductase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal; PRIAM: Tagaturonate reductase; SPTR: Mannitol dehydrogenase, C-terminal domain; IMG reference gene:2504918884; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain; Tagaturonate reductase 21116 10578496 Trebr_0019 Treponema brennaborense DSM 12168 Tagaturonate reductase YP_004438610.1 19638 R 906968 CDS YP_004438611.1 332296689 10578497 21295..24633 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR018060:IPR000005; KEGG: rca:Rcas_3135 PAS/PAC sensor hybrid histidine kinase; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: PAS/PAC sensor hybrid histidine kinase; IMG reference gene:2504918885; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; family; AraC family transcriptional regulator 24633 10578497 Trebr_0020 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004438611.1 21295 D 906968 CDS YP_004438612.1 332296690 10578498 24801..25730 1 NC_015500.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: mrb:Mrub_0281 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504918886; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 25730 10578498 Trebr_0021 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438612.1 24801 D 906968 CDS YP_004438613.1 332296691 10578499 25743..26645 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: mrb:Mrub_0280 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504918887; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 26645 10578499 Trebr_0022 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438613.1 25743 D 906968 CDS YP_004438614.1 332296692 10578500 26731..28299 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: mrb:Mrub_0279 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504918888; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 28299 10578500 Trebr_0023 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438614.1 26731 D 906968 CDS YP_004438615.1 332296693 10578502 30297..33071 1 NC_015500.1 KEGG: tde:TDE1985 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918890; PFAM: FecR protein; hypothetical protein 33071 10578502 Trebr_0025 Treponema brennaborense DSM 12168 hypothetical protein YP_004438615.1 30297 D 906968 CDS YP_004438616.1 332296694 10578503 33061..34293 1 NC_015500.1 KEGG: tde:TDE1984 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918891; hypothetical protein 34293 10578503 Trebr_0026 Treponema brennaborense DSM 12168 hypothetical protein YP_004438616.1 33061 D 906968 CDS YP_004438617.1 332296695 10578504 34295..36961 1 NC_015500.1 KEGG: tde:TDE1933 hypothetical protein; SPTR: Polymorphic outer membrane protein; IMG reference gene:2504918892; hypothetical protein 36961 10578504 Trebr_0027 Treponema brennaborense DSM 12168 hypothetical protein YP_004438617.1 34295 D 906968 CDS YP_004438618.1 332296696 10578505 36975..40076 1 NC_015500.1 InterPro IPR006626:IPR003368; KEGG: rba:RB4375 extracellular nuclease; PFAM: Polymorphic membrane protein, Chlamydia; SPTR: Polymorphic outer membrane protein; TIGRFAM: Polymorphic membrane protein, Chlamydia; IMG reference gene:2504918893; polymorphic outer membrane protein 40076 10578505 Trebr_0028 Treponema brennaborense DSM 12168 polymorphic outer membrane protein YP_004438618.1 36975 D 906968 CDS YP_004438619.1 332296697 10578506 40643..40861 1 NC_015500.1 IMG reference gene:2504918894; hypothetical protein 40861 10578506 Trebr_0029 Treponema brennaborense DSM 12168 hypothetical protein YP_004438619.1 40643 D 906968 CDS YP_004438620.1 332296698 10578507 40946..41638 1 NC_015500.1 KEGG: dps:DP2996 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918895; hypothetical protein 41638 10578507 Trebr_0030 Treponema brennaborense DSM 12168 hypothetical protein YP_004438620.1 40946 D 906968 CDS YP_004438621.1 332296699 10578508 41735..42487 1 NC_015500.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: tde:TDE2713 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family; IMG reference gene:2504918896; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; tRNA/rRNA methyltransferase SpoU 42487 10578508 Trebr_0031 Treponema brennaborense DSM 12168 tRNA/rRNA methyltransferase SpoU YP_004438621.1 41735 D 906968 CDS YP_004438622.1 332296700 10578509 42622..43137 1 NC_015500.1 COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: ele:Elen_2134 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918897; PFAM: Uracil DNA glycosylase superfamily; hypothetical protein 43137 10578509 Trebr_0032 Treponema brennaborense DSM 12168 hypothetical protein YP_004438622.1 42622 D 906968 CDS YP_004438623.1 332296701 10578510 43317..44192 1 NC_015500.1 InterPro IPR000326; KEGG: sli:Slin_1798 phosphoesterase PA-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Phosphoesterase PA-phosphatase related protein; IMG reference gene:2504918898; PFAM: PAP2 superfamily; phosphoesterase PA-phosphatase-like protein 44192 10578510 Trebr_0033 Treponema brennaborense DSM 12168 phosphoesterase PA-phosphatase-like protein YP_004438623.1 43317 D 906968 CDS YP_004438624.1 332296702 10578511 44197..44742 1 NC_015500.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: ele:Elen_1720 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504918899; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family; phosphodiesterase, MJ0936 family 44742 10578511 Trebr_0034 Treponema brennaborense DSM 12168 phosphodiesterase, MJ0936 family YP_004438624.1 44197 D 906968 CDS YP_004438625.1 332296703 10578512 complement(44722..45180) 1 NC_015500.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: csh:Closa_2673 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: Transcriptional regulator, Rrf2; IMG reference gene:2504918900; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; asnc family transcriptional regulator 45180 10578512 Trebr_0035 Treponema brennaborense DSM 12168 asnc family transcriptional regulator YP_004438625.1 44722 R 906968 CDS YP_004438626.1 332296704 10578513 complement(45240..46721) 1 NC_015500.1 COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR002129; KEGG: bpu:BPUM_1020 diaminobutyrate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase; PRIAM: Diaminobutyrate decarboxylase; SPTR: L-2,4-diaminobutyrate decarboxylase (Daba decarboxylase)(Daba-dc); IMG reference gene:2504918901; PFAM: Pyridoxal-dependent decarboxylase conserved domain; diaminobutyrate decarboxylase 46721 10578513 Trebr_0036 Treponema brennaborense DSM 12168 diaminobutyrate decarboxylase YP_004438626.1 45240 R 906968 CDS YP_004438627.1 332296705 10578514 complement(46708..48069) 1 NC_015500.1 COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814:IPR004637; KEGG: pva:Pvag_pPag30242 diaminobutyrate--2-oxoglutarateaminotransferase; PFAM: Aminotransferase class-III; PRIAM: Diaminobutyrate--2-oxoglutarate transaminase; SPTR: Diaminobutyrate--2-oxoglutarate aminotransferase; TIGRFAM: Diaminobutyrate-2-oxoglutarate transaminase; IMG reference gene:2504918902; PFAM: Aminotransferase class-III; TIGRFAM: 2,4-diaminobutyrate 4-transaminases; 2,4-diaminobutyrate 4-transaminase 48069 10578514 Trebr_0037 Treponema brennaborense DSM 12168 2,4-diaminobutyrate 4-transaminase YP_004438627.1 46708 R 906968 CDS YP_004438628.1 332296706 10578516 48765..49664 1 NC_015500.1 COGs: COG2035 membrane protein; InterPro IPR007163; KEGG: lme:LEUM_1472 hypothetical protein; PFAM: Protein of unknown function DUF368; SPTR: uncharacterized protein; IMG reference gene:2504918904; PFAM: Domain of unknown function (DUF368); hypothetical protein 49664 10578516 Trebr_0039 Treponema brennaborense DSM 12168 hypothetical protein YP_004438628.1 48765 D 906968 CDS YP_004438629.1 332296707 10578517 complement(49785..50345) 1 NC_015500.1 IMG reference gene:2504918905; hypothetical protein 50345 10578517 Trebr_0040 Treponema brennaborense DSM 12168 hypothetical protein YP_004438629.1 49785 R 906968 CDS YP_004438630.1 332296708 10578518 complement(50399..51073) 1 NC_015500.1 InterPro IPR012506; KEGG: tde:TDE2729 hypothetical protein; PFAM: YhhN-like; SPTR: Membrane protein, ; IMG reference gene:2504918906; PFAM: YhhN-like protein; hypothetical protein 51073 10578518 Trebr_0041 Treponema brennaborense DSM 12168 hypothetical protein YP_004438630.1 50399 R 906968 CDS YP_004438631.1 332296709 10578519 51380..52699 1 NC_015500.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: cpy:Cphy_0769 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 4; PRIAM: Alpha-galactosidase; SPTR: Glycoside hydrolase family 4; IMG reference gene:2504918907; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; Alpha-galactosidase 52699 10578519 Trebr_0042 Treponema brennaborense DSM 12168 Alpha-galactosidase YP_004438631.1 51380 D 906968 CDS YP_004438632.1 332296710 10578520 52784..54043 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cbe:Cbei_4445 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein; IMG reference gene:2504918908; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 54043 10578520 Trebr_0043 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438632.1 52784 D 906968 CDS YP_004438633.1 332296711 10578521 54134..55033 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sak:SAK_0533 sugar ABC transporter, permease protein, PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family (TC 3.A.1.1.-); IMG reference gene:2504918909; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 55033 10578521 Trebr_0044 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438633.1 54134 D 906968 CDS YP_004438634.1 332296712 10578522 55111..55941 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; IMG reference gene:2504918910; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 55941 10578522 Trebr_0045 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438634.1 55111 D 906968 CDS YP_004438635.1 332296713 10578523 complement(55893..56768) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR003313:IPR000005; KEGG: csh:Closa_0320 transcriptional regulator, AraC family; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504918911; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; AraC family transcriptional regulator 56768 10578523 Trebr_0046 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004438635.1 55893 R 906968 CDS YP_004438636.1 332296714 10578524 complement(56838..57323) 1 NC_015500.1 COGs: COG3467 flavin-nucleotide-binding protein; KEGG: fsu:Fisuc_2301 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; SPTR: Predicted flavin-nucleotide-binding protein; IMG reference gene:2504918912; PFAM: Pyridoxamine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-related FMN-binding protein 57323 10578524 Trebr_0047 Treponema brennaborense DSM 12168 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein YP_004438636.1 56838 R 906968 CDS YP_004438637.1 332296715 10578525 complement(57475..58848) 1 NC_015500.1 COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR001926:IPR006316; KEGG: ccb:Clocel_2504 pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Pyridoxal-phosphate dependent TrpB-like enzyme; TIGRFAM: Tryptophan synthase, beta chain-like; IMG reference gene:2504918913; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; pyridoxal-phosphate dependent TrpB-like protein 58848 10578525 Trebr_0048 Treponema brennaborense DSM 12168 pyridoxal-phosphate dependent TrpB-like protein YP_004438637.1 57475 R 906968 CDS YP_004438638.1 332296716 10578526 complement(59122..59451) 1 NC_015500.1 InterPro IPR001387; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; IMG reference gene:2504918914; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 59451 10578526 Trebr_0049 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004438638.1 59122 R 906968 CDS YP_004438639.1 332296717 10578527 59620..60735 1 NC_015500.1 KEGG: cbe:Cbei_1299 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918915; PFAM: Acyltransferase family; hypothetical protein 60735 10578527 Trebr_0050 Treponema brennaborense DSM 12168 hypothetical protein YP_004438639.1 59620 D 906968 CDS YP_004438640.1 332296718 10578528 complement(60800..61750) 1 NC_015500.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: brm:Bmur_2337 auxin efflux carrier; PFAM: Auxin efflux carrier; SPTR: Auxin Efflux Carrier; IMG reference gene:2504918916; PFAM: Membrane transport protein; auxin efflux carrier family protein 61750 10578528 Trebr_0051 Treponema brennaborense DSM 12168 auxin efflux carrier family protein YP_004438640.1 60800 R 906968 CDS YP_004438641.1 332296719 10578529 complement(61771..62409) 1 NC_015500.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: bcg:BCG9842_B4923 L-fuculose phosphate aldolase; PFAM: Class II aldolase/adducin, N-terminal; PRIAM: L-fuculose-phosphate aldolase; SPTR: Aldolase, class II; IMG reference gene:2504918917; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; L-fuculose-phosphate aldolase 62409 10578529 Trebr_0052 Treponema brennaborense DSM 12168 L-fuculose-phosphate aldolase YP_004438641.1 61771 R 906968 CDS YP_004438642.1 332296720 10578530 complement(62460..63503) 1 NC_015500.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: elm:ELI_0529 hypothetical protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: uncharacterized protein; IMG reference gene:2504918918; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Phosphoglycerate dehydrogenase 63503 10578530 Trebr_0053 Treponema brennaborense DSM 12168 Phosphoglycerate dehydrogenase YP_004438642.1 62460 R 906968 CDS YP_004438643.1 332296721 10578531 complement(63618..65141) 1 NC_015500.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: elm:ELI_0528 hypothetical protein; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: L-xylulokinase; SPTR: uncharacterized protein; IMG reference gene:2504918919; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; L-xylulokinase 65141 10578531 Trebr_0054 Treponema brennaborense DSM 12168 L-xylulokinase YP_004438643.1 63618 R 906968 CDS YP_004438644.1 332296722 10578532 complement(65258..66211) 1 NC_015500.1 COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: elm:ELI_0527 hypothetical protein; PFAM: sugar-binding region; SPTR: uncharacterized protein; IMG reference gene:2504918920; PFAM: sugar-binding domain; Cro/CI family transcriptional regulator -like protein 66211 10578532 Trebr_0055 Treponema brennaborense DSM 12168 Cro/CI family transcriptional regulator -like protein YP_004438644.1 65258 R 906968 CDS YP_004438645.1 332296723 10578533 complement(66291..66509) 1 NC_015500.1 COGs: COG4877 conserved hypothetical protein; KEGG: cst:CLOST_2156 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918921; hypothetical protein 66509 10578533 Trebr_0056 Treponema brennaborense DSM 12168 hypothetical protein YP_004438645.1 66291 R 906968 CDS YP_004438646.1 332296724 10578534 complement(66513..67541) 1 NC_015500.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: eel:EUBELI_02036 hypothetical protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: uncharacterized protein; IMG reference gene:2504918922; PFAM: SPFH domain / Band 7 family; hypothetical protein 67541 10578534 Trebr_0057 Treponema brennaborense DSM 12168 hypothetical protein YP_004438646.1 66513 R 906968 CDS YP_004438647.1 332296725 10578535 complement(67768..70098) 1 NC_015500.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003439; KEGG: bln:Blon_1685 ABC transporter related; PFAM: ABC transporter-like; SPTR: ABC transporter related protein; IMG reference gene:2504918923; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit; ABC transporter 70098 10578535 Trebr_0058 Treponema brennaborense DSM 12168 ABC transporter YP_004438647.1 67768 R 906968 CDS YP_004438648.1 332296726 10578536 complement(70173..71024) 1 NC_015500.1 COGs: COG0384 epimerase PhzC/PhzF homolog; InterPro IPR003719; KEGG: cba:CLB_2120 PhzF family phenazine biosynthesis protein; PFAM: Phenazine biosynthesis PhzC/PhzF protein; SPTR: Phenazine biosynthesis protein, PhzF family; TIGRFAM: Phenazine biosynthesis PhzC/PhzF protein; IMG reference gene:2504918924; PFAM: Phenazine biosynthesis-like protein; TIGRFAM: phenazine biosynthesis protein PhzF family; phenazine biosynthesis protein PhzF family 71024 10578536 Trebr_0059 Treponema brennaborense DSM 12168 phenazine biosynthesis protein PhzF family YP_004438648.1 70173 R 906968 CDS YP_004438649.1 332296727 10578537 complement(71057..71551) 1 NC_015500.1 InterPro IPR005358; KEGG: sss:SSUSC84_0904 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Predicted Fe-S-cluster oxidoreductase; manually curated; IMG reference gene:2504918925; PFAM: Uncharacterised protein family (UPF0153); hypothetical protein 71551 10578537 Trebr_0060 Treponema brennaborense DSM 12168 hypothetical protein YP_004438649.1 71057 R 906968 CDS YP_004438650.1 332296728 10578538 complement(71717..72400) 1 NC_015500.1 InterPro IPR011576; KEGG: str:Sterm_2242 hypothetical protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: uncharacterized protein; IMG reference gene:2504918926; PFAM: Pyridoxamine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-related FMN-binding protein 72400 10578538 Trebr_0061 Treponema brennaborense DSM 12168 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein YP_004438650.1 71717 R 906968 CDS YP_004438651.1 332296729 10578539 complement(72581..73801) 1 NC_015500.1 COGs: COG1015 Phosphopentomutase; HAMAP: Phosphopentomutase; InterPro IPR013553:IPR006124:IPR010045; KEGG: cpf:CPF_0376 phosphopentomutase; PRIAM: Phosphopentomutase; SPTR: Phosphopentomutase; TIGRFAM: Phosphopentomutase; IMG reference gene:2504918927; PFAM: Metalloenzyme superfamily; TIGRFAM: phosphopentomutase; Phosphopentomutase 73801 10578539 Trebr_0062 Treponema brennaborense DSM 12168 Phosphopentomutase YP_004438651.1 72581 R 906968 CDS YP_004438652.1 332296730 10578540 complement(73791..74597) 1 NC_015500.1 COGs: COG2820 Uridine phosphorylase; InterPro IPR000845:IPR010058; KEGG: sak:SAK_2011 uridine phosphorylase; PFAM: Nucleoside phosphorylase; PRIAM: Uridine phosphorylase; SPTR: uncharacterized protein; TIGRFAM: Uridine phosphorylase; IMG reference gene:2504918928; PFAM: Phosphorylase superfamily; TIGRFAM: uridine phosphorylase; uridine phosphorylase 74597 10578540 Trebr_0063 Treponema brennaborense DSM 12168 uridine phosphorylase YP_004438652.1 73791 R 906968 CDS YP_004438653.1 332296731 10578541 75230..75385 1 NC_015500.1 IMG reference gene:2504918929; hypothetical protein 75385 10578541 Trebr_0064 Treponema brennaborense DSM 12168 hypothetical protein YP_004438653.1 75230 D 906968 CDS YP_004438654.1 332296732 10578542 75462..77024 1 NC_015500.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ssm:Spirs_1043 5'-nucleotidase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: 5'-nucleotidase; IMG reference gene:2504918930; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; 5'-nucleotidase 77024 10578542 Trebr_0065 Treponema brennaborense DSM 12168 5'-nucleotidase YP_004438654.1 75462 D 906968 CDS YP_004438655.1 332296733 10578543 77171..78187 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ipo:Ilyop_0110 transcriptional regulator, LacI family; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504918931; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 78187 10578543 Trebr_0066 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004438655.1 77171 D 906968 CDS YP_004438656.1 332296734 10578544 78223..79749 1 NC_015500.1 COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: cbt:CLH_2725 galactose/methyl galactoside import ATP-binding protein MglA; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Sugar ABC transporter, ATP-binding protein; IMG reference gene:2504918932; PFAM: ABC transporter; monosaccharide-transporting ATPase 79749 10578544 Trebr_0067 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004438656.1 78223 D 906968 CDS YP_004438657.1 332296735 10578545 79736..80779 1 NC_015500.1 COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: cpr:CPR_1550 ABC transporter permease; PFAM: Bacterial inner-membrane translocator; SPTR: ABC transporter, permease protein; IMG reference gene:2504918933; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 80779 10578545 Trebr_0068 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438657.1 79736 D 906968 CDS YP_004438658.1 332296736 10578546 80789..81736 1 NC_015500.1 COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: cpe:CPE1577 ABC transporter; PFAM: Bacterial inner-membrane translocator; SPTR: ABC transporter; IMG reference gene:2504918934; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 81736 10578546 Trebr_0069 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438658.1 80789 D 906968 CDS YP_004438659.1 332296737 10578547 81864..82514 1 NC_015500.1 COGs: COG0274 Deoxyribose-phosphate aldolase; HAMAP: Deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: ipo:Ilyop_1462 deoxyribose-phosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: Deoxyribose-phosphate aldolase; TIGRFAM: Deoxyribose-phosphate aldolase; IMG reference gene:2504918935; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase; Deoxyribose-phosphate aldolase 82514 10578547 Trebr_0070 Treponema brennaborense DSM 12168 Deoxyribose-phosphate aldolase YP_004438659.1 81864 D 906968 CDS YP_004438660.1 332296738 10578548 82612..83673 1 NC_015500.1 COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: cbk:CLL_A2974 membrane lipoprotein TmpC; PFAM: Basic membrane lipoprotein; SPTR: Membrane lipoprotein tmpc; IMG reference gene:2504918936; PFAM: Basic membrane protein; basic membrane lipoprotein 83673 10578548 Trebr_0071 Treponema brennaborense DSM 12168 basic membrane lipoprotein YP_004438660.1 82612 D 906968 CDS YP_004438661.1 332296739 10578549 complement(83960..84622) 1 NC_015500.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR006402; KEGG: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; manually curated; IMG reference gene:2504918937; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; HAD-superfamily hydrolase 84622 10578549 Trebr_0072 Treponema brennaborense DSM 12168 HAD-superfamily hydrolase YP_004438661.1 83960 R 906968 CDS YP_004438662.1 332296740 10578551 complement(85591..85920) 1 NC_015500.1 IMG reference gene:2504918939; hypothetical protein 85920 10578551 Trebr_0074 Treponema brennaborense DSM 12168 hypothetical protein YP_004438662.1 85591 R 906968 CDS YP_004438663.1 332296741 10578552 complement(85932..86417) 1 NC_015500.1 IMG reference gene:2504918940; PFAM: Curli production assembly/transport component CsgG; hypothetical protein 86417 10578552 Trebr_0075 Treponema brennaborense DSM 12168 hypothetical protein YP_004438663.1 85932 R 906968 CDS YP_004438664.1 332296742 10578554 complement(86802..86951) 1 NC_015500.1 KEGG: tde:TDE0196 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918942; PFAM: Uncharacterized protein conserved in bacteria (DUF2191); hypothetical protein 86951 10578554 Trebr_0077 Treponema brennaborense DSM 12168 hypothetical protein YP_004438664.1 86802 R 906968 CDS YP_004438665.1 332296743 10578555 complement(87346..87813) 1 NC_015500.1 InterPro IPR000182; KEGG: bay:RBAM_024110 YrkN; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504918943; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 87813 10578555 Trebr_0078 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004438665.1 87346 R 906968 CDS YP_004438666.1 332296744 10578556 complement(88212..88688) 1 NC_015500.1 IMG reference gene:2504918944; hypothetical protein 88688 10578556 Trebr_0079 Treponema brennaborense DSM 12168 hypothetical protein YP_004438666.1 88212 R 906968 CDS YP_004438667.1 332296745 10578557 complement(89050..89898) 1 NC_015500.1 KEGG: ppy:PPE_01337 methyltransferase type 11; SPTR: Methyltransferase type 11; IMG reference gene:2504918945; hypothetical protein 89898 10578557 Trebr_0080 Treponema brennaborense DSM 12168 hypothetical protein YP_004438667.1 89050 R 906968 CDS YP_004438668.1 332296746 10578558 complement(89991..90818) 1 NC_015500.1 KEGG: dde:Dde_0890 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918946; hypothetical protein 90818 10578558 Trebr_0081 Treponema brennaborense DSM 12168 hypothetical protein YP_004438668.1 89991 R 906968 CDS YP_004438669.1 332296747 10578559 91066..92196 1 NC_015500.1 COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR003346; KEGG: bpb:bpr_IV010 IS110 family transposase; PFAM: Transposase, IS116/IS110/IS902; SPTR: ISCps8, transposase; IMG reference gene:2504918947; PFAM: Transposase IS116/IS110/IS902 family; Transposase; transposase IS116/IS110/IS902 family protein 92196 10578559 Trebr_0082 Treponema brennaborense DSM 12168 transposase IS116/IS110/IS902 family protein YP_004438669.1 91066 D 906968 CDS YP_004438670.1 332296748 10578561 complement(93533..94732) 1 NC_015500.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: mar:MAE_14190 site-specific DNA-methyltransferase; PFAM: DNA methylase N-4/N-6; SPTR: Site-specific DNA-methyltransferase (Cytosine-N4-specific); IMG reference gene:2504918949; PFAM: DNA methylase; DNA methylase N-4/N-6 domain-containing protein 94732 10578561 Trebr_0084 Treponema brennaborense DSM 12168 DNA methylase N-4/N-6 domain-containing protein YP_004438670.1 93533 R 906968 CDS YP_004438671.1 332296749 10578563 complement(95433..96149) 1 NC_015500.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: tde:TDE1608 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: uncharacterized protein; IMG reference gene:2504918951; PFAM: Methyltransferase domain; type 11 methyltransferase 96149 10578563 Trebr_0086 Treponema brennaborense DSM 12168 type 11 methyltransferase YP_004438671.1 95433 R 906968 CDS YP_004438672.1 332296750 10578564 96346..97332 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ssm:Spirs_0361 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504918952; PFAM: ABC transporter; sulfate-transporting ATPase 97332 10578564 Trebr_0087 Treponema brennaborense DSM 12168 sulfate-transporting ATPase YP_004438672.1 96346 D 906968 CDS YP_004438673.1 332296751 10578565 97325..98224 1 NC_015500.1 InterPro IPR013525; KEGG: ssm:Spirs_0360 ABC-type transport system, membrane protein; PFAM: ABC-2 type transporter; SPTR: ABC-type transport system, membrane protein; IMG reference gene:2504918953; ABC transporter 98224 10578565 Trebr_0088 Treponema brennaborense DSM 12168 ABC transporter YP_004438673.1 97325 D 906968 CDS YP_004438674.1 332296752 10578566 98228..100441 1 NC_015500.1 InterPro IPR019196; KEGG: ssm:Spirs_0359 ABC-type uncharacterized transport system; PFAM: ABC-type uncharacterised transport system; SPTR: ABC-type uncharacterized transport system; IMG reference gene:2504918954; PFAM: ABC-type uncharacterized transport system; ABC transporter 100441 10578566 Trebr_0089 Treponema brennaborense DSM 12168 ABC transporter YP_004438674.1 98228 D 906968 CDS YP_004438675.1 332296753 10578567 100438..101442 1 NC_015500.1 KEGG: ssm:Spirs_0358 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918955; hypothetical protein 101442 10578567 Trebr_0090 Treponema brennaborense DSM 12168 hypothetical protein YP_004438675.1 100438 D 906968 CDS YP_004438676.1 332296754 10578568 complement(101569..103179) 1 NC_015500.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: eel:EUBELI_20594 fructuronate reductase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal; PRIAM: Mannitol 2-dehydrogenase; SPTR: Mannitol dehydrogenase; IMG reference gene:2504918956; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain; mannitol 2-dehydrogenase 103179 10578568 Trebr_0091 Treponema brennaborense DSM 12168 mannitol 2-dehydrogenase YP_004438676.1 101569 R 906968 CDS YP_004438677.1 332296755 10578569 complement(103191..104270) 1 NC_015500.1 COGs: COG1312 D-mannonate dehydratase; HAMAP: Mannonate dehydratase; InterPro IPR004628; KEGG: bpb:bpr_I0685 D-mannonate dehydratase UxuA; PFAM: Mannonate dehydratase; PRIAM: Mannonate dehydratase; SPTR: Mannonate dehydratase; TIGRFAM: Mannonate dehydratase; IMG reference gene:2504918957; PFAM: D-mannonate dehydratase (UxuA); TIGRFAM: mannonate dehydratase; mannonate dehydratase 104270 10578569 Trebr_0092 Treponema brennaborense DSM 12168 mannonate dehydratase YP_004438677.1 103191 R 906968 CDS YP_004438678.1 332296756 10578570 complement(104302..105600) 1 NC_015500.1 COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR010656:IPR004681; KEGG: asu:Asuc_0368 TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; IMG reference gene:2504918958; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; TRAP dicarboxylate transporter subunit DctM 105600 10578570 Trebr_0093 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctM YP_004438678.1 104302 R 906968 CDS YP_004438679.1 332296757 10578571 complement(105645..106178) 1 NC_015500.1 COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: asu:Asuc_0367 tripartite ATP-independent periplasmic transporter DctQ; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component; IMG reference gene:2504918959; PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; tripartite AtP-independent periplasmic transporter subunit DctQ 106178 10578571 Trebr_0094 Treponema brennaborense DSM 12168 tripartite AtP-independent periplasmic transporter subunit DctQ YP_004438679.1 105645 R 906968 CDS YP_004438680.1 332296758 10578572 complement(106294..107316) 1 NC_015500.1 COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389:IPR004682; KEGG: asu:Asuc_0366 TRAP dicarboxylate transporter, DctP subunit; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; IMG reference gene:2504918960; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP 107316 10578572 Trebr_0095 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctP YP_004438680.1 106294 R 906968 CDS YP_004438681.1 332296759 10578573 107621..108643 1 NC_015500.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: bss:BSUW23_06280 oxidoreductase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; PRIAM: L-threonine 3-dehydrogenase; SPTR: YjmD; IMG reference gene:2504918961; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; L-threonine 3-dehydrogenase 108643 10578573 Trebr_0096 Treponema brennaborense DSM 12168 L-threonine 3-dehydrogenase YP_004438681.1 107621 D 906968 CDS YP_004438682.1 332296760 10578574 108676..109692 1 NC_015500.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: efe:EFER_2666 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; PRIAM: L-iditol 2-dehydrogenase; SPTR: uncharacterized protein; IMG reference gene:2504918962; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; L-iditol 2-dehydrogenase 109692 10578574 Trebr_0097 Treponema brennaborense DSM 12168 L-iditol 2-dehydrogenase YP_004438682.1 108676 D 906968 CDS YP_004438683.1 332296761 10578575 109784..110509 1 NC_015500.1 COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: has:Halsa_0900 transcriptional regulator, GntR family; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Regulatory protein, GntR family; IMG reference gene:2504918963; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 110509 10578575 Trebr_0098 Treponema brennaborense DSM 12168 GntR family transcriptional regulator YP_004438683.1 109784 D 906968 CDS YP_004438684.1 332296762 10578576 complement(110623..111423) 1 NC_015500.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: bfs:BF0083 gluconate 5-dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Gluconate 5-dehydrogenase; SPTR: Oxidoreductase, short chain dehydrogenase/reductase family protein; IMG reference gene:2504918964; PFAM: short chain dehydrogenase; Gluconate 5-dehydrogenase 111423 10578576 Trebr_0099 Treponema brennaborense DSM 12168 Gluconate 5-dehydrogenase YP_004438684.1 110623 R 906968 CDS YP_004438685.1 332296763 10578577 complement(111535..112005) 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: glo:Glov_1734 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein; IMG reference gene:2504918965; PFAM: CheW-like domain; CheW protein 112005 10578577 Trebr_0100 Treponema brennaborense DSM 12168 CheW protein YP_004438685.1 111535 R 906968 CDS YP_004438686.1 332296764 10578578 complement(112075..112572) 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dma:DMR_23770 chemotaxis protein CheW; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Chemotaxis protein CheW; IMG reference gene:2504918966; PFAM: CheW-like domain; CheW protein 112572 10578578 Trebr_0101 Treponema brennaborense DSM 12168 CheW protein YP_004438686.1 112075 R 906968 CDS YP_004438687.1 332296765 10578579 complement(112589..112957) 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: gsu:GSU1289 chemotaxis protein CheY; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Chemotaxis protein CheY; IMG reference gene:2504918967; PFAM: Response regulator receiver domain; response regulator receiver protein 112957 10578579 Trebr_0102 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004438687.1 112589 R 906968 CDS YP_004438688.1 332296766 10578580 complement(113101..114210) 1 NC_015500.1 COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; HAMAP: Chemotaxis response regulator protein-glutamate methylesterase; InterPro IPR001789:IPR000673; KEGG: ssm:Spirs_1823 response regulator receiver modulated CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; Signal transduction response regulator, receiver region; PRIAM: Protein-glutamate methylesterase; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver modulated CheB methylesterase; IMG reference gene:2504918968; PFAM: CheB methylesterase; Response regulator receiver domain; response regulator receiver modulated CheB methylesterase 114210 10578580 Trebr_0103 Treponema brennaborense DSM 12168 response regulator receiver modulated CheB methylesterase YP_004438688.1 113101 R 906968 CDS YP_004438689.1 332296767 10578581 complement(114210..115064) 1 NC_015500.1 COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: CheR-type MCP methyltransferase; PFAM: MCP methyltransferase, CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type; IMG reference gene:2504918969; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; CheR-type MCP methyltransferase 115064 10578581 Trebr_0104 Treponema brennaborense DSM 12168 CheR-type MCP methyltransferase YP_004438689.1 114210 R 906968 CDS YP_004438690.1 332296768 10578582 complement(115068..117230) 1 NC_015500.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR004105; KEGG: ppd:Ppro_1607 CheA signal transduction histidine kinases; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SPTR: CheA signal transduction histidine kinase; IMG reference gene:2504918970; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; CheA signal transduction histidine kinase 117230 10578582 Trebr_0105 Treponema brennaborense DSM 12168 CheA signal transduction histidine kinase YP_004438690.1 115068 R 906968 CDS YP_004438691.1 332296769 10578583 complement(117223..117573) 1 NC_015500.1 IMG reference gene:2504918971; PFAM: STAS domain; hypothetical protein 117573 10578583 Trebr_0106 Treponema brennaborense DSM 12168 hypothetical protein YP_004438691.1 117223 R 906968 CDS YP_004438692.1 332296770 10578584 117731..118207 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mgm:Mmc1_3653 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein; IMG reference gene:2504918972; PFAM: CheW-like domain; CheW protein 118207 10578584 Trebr_0107 Treponema brennaborense DSM 12168 CheW protein YP_004438692.1 117731 D 906968 CDS YP_004438693.1 332296771 10578585 complement(118232..118825) 1 NC_015500.1 COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; HAMAP: Chemoreceptor glutamine deamidase cheD; InterPro IPR005659; KEGG: sbl:Sbal_2116 chemoreceptor glutamine deamidase CheD; PFAM: Chemoreceptor glutamine deamidase cheD; PRIAM: Protein-glutamine glutaminase; SPTR: Probable chemoreceptor glutamine deamidase CheD; IMG reference gene:2504918973; PFAM: CheD; protein CheD 118825 10578585 Trebr_0108 Treponema brennaborense DSM 12168 protein CheD YP_004438693.1 118232 R 906968 CDS YP_004438694.1 332296772 10578586 complement(118834..120597) 1 NC_015500.1 KEGG: ssm:Spirs_0578 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918974; hypothetical protein 120597 10578586 Trebr_0109 Treponema brennaborense DSM 12168 hypothetical protein YP_004438694.1 118834 R 906968 CDS YP_004438695.1 332296773 10578587 complement(120599..121585) 1 NC_015500.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: ssm:Spirs_1797 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; IMG reference gene:2504918975; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase 121585 10578587 Trebr_0110 Treponema brennaborense DSM 12168 cobyrinic acid ac-diamide synthase YP_004438695.1 120599 R 906968 CDS YP_004438696.1 332296774 10578588 complement(121719..122840) 1 NC_015500.1 KEGG: pin:Ping_1180 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918976; PFAM: Acyltransferase family; hypothetical protein 122840 10578588 Trebr_0111 Treponema brennaborense DSM 12168 hypothetical protein YP_004438696.1 121719 R 906968 CDS YP_004438697.1 332296775 10578589 123042..123356 1 NC_015500.1 InterPro IPR001387; KEGG: oca:OCAR_6455 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Conserved domain protein; IMG reference gene:2504918977; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 123356 10578589 Trebr_0112 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004438697.1 123042 D 906968 CDS YP_004438698.1 332296776 10578590 123486..124874 1 NC_015500.1 COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cth:Cthe_3027 citrate synthase; PFAM: Citrate synthase-like; SPTR: Citrate (Si)-synthase; IMG reference gene:2504918978; PFAM: Citrate synthase; Citrate synthase 124874 10578590 Trebr_0113 Treponema brennaborense DSM 12168 Citrate synthase YP_004438698.1 123486 D 906968 CDS YP_004438699.1 332296777 10578591 complement(124919..127426) 1 NC_015500.1 KEGG: tde:TDE1984 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504918979; hypothetical protein 127426 10578591 Trebr_0114 Treponema brennaborense DSM 12168 hypothetical protein YP_004438699.1 124919 R 906968 CDS YP_004438700.1 332296778 10578592 complement(127416..130433) 1 NC_015500.1 InterPro IPR006860; KEGG: tde:TDE1985 hypothetical protein; PFAM: FecR protein; SPTR: uncharacterized protein; IMG reference gene:2504918980; PFAM: FecR protein; FecR protein 130433 10578592 Trebr_0115 Treponema brennaborense DSM 12168 FecR protein YP_004438700.1 127416 R 906968 CDS YP_004438701.1 332296779 10578593 complement(130393..132852) 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054; KEGG: tde:TDE1986 adenylate cyclase, PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Adenylate cyclase; IMG reference gene:2504918981; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; adenylate/guanylate cyclase with integral membrane sensor 132852 10578593 Trebr_0116 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase with integral membrane sensor YP_004438701.1 130393 R 906968 CDS YP_004438702.1 332296780 10578594 132955..134145 1 NC_015500.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); KEGG: sta:STHERM_c01250 leucyl aminopeptidase; SPTR: leucyl aminopeptidase; IMG reference gene:2504918982; PFAM: Thermophilic metalloprotease (M29); leucyl aminopeptidase 134145 10578594 Trebr_0117 Treponema brennaborense DSM 12168 leucyl aminopeptidase YP_004438702.1 132955 D 906968 CDS YP_004438703.1 332296781 10578595 complement(134295..135239) 1 NC_015500.1 InterPro IPR004199; PFAM: Glycoside hydrolase, family 42, domain 5; IMG reference gene:2504918983; PFAM: pfkB family carbohydrate kinase; Beta galactosidase small chain; glycoside hydrolase family protein 135239 10578595 Trebr_0118 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004438703.1 134295 R 906968 CDS YP_004438704.1 332296782 10578596 complement(135385..138552) 1 NC_015500.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006103:IPR004199; KEGG: rca:Rcas_2493 beta-galactosidase; PFAM: Glycoside hydrolase family 2, TIM barrel; Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase, family 42, domain 5; SPTR: Glycoside hydrolase family 2 TIM barrel; IMG reference gene:2504918984; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain; glycoside hydrolase family protein 138552 10578596 Trebr_0119 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004438704.1 135385 R 906968 CDS YP_004438705.1 332296783 10578597 138719..140014 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cpy:Cphy_3590 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504918985; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 140014 10578597 Trebr_0120 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438705.1 138719 D 906968 CDS YP_004438706.1 332296784 10578598 140127..141014 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: cpy:Cphy_3589 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504918986; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 141014 10578598 Trebr_0121 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438706.1 140127 D 906968 CDS YP_004438707.1 332296785 10578599 141001..141816 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_3588 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504918987; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 141816 10578599 Trebr_0122 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438707.1 141001 D 906968 CDS YP_004438708.1 332296786 10578600 complement(141818..142495) 1 NC_015500.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ssm:Spirs_4097 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504918988; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; two component transcriptional regulator, LuxR family 142495 10578600 Trebr_0123 Treponema brennaborense DSM 12168 two component transcriptional regulator, LuxR family YP_004438708.1 141818 R 906968 CDS YP_004438709.1 332296787 10578601 complement(142485..143789) 1 NC_015500.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: ssm:Spirs_1060 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; SMART: ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504918989; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 143789 10578601 Trebr_0124 Treponema brennaborense DSM 12168 signal transduction histidine kinase YP_004438709.1 142485 R 906968 CDS YP_004438710.1 332296788 10578602 complement(144013..145161) 1 NC_015500.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670:IPR013460; KEGG: eel:EUBELI_20348 L-1,2-propanediol oxidoreductase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Lactaldehyde reductase; SPTR: Lactaldehyde reductase; TIGRFAM: Lactaldehyde reductase; IMG reference gene:2504918990; PFAM: Iron-containing alcohol dehydrogenase; TIGRFAM: lactaldehyde reductase; lactaldehyde reductase 145161 10578602 Trebr_0125 Treponema brennaborense DSM 12168 lactaldehyde reductase YP_004438710.1 144013 R 906968 CDS YP_004438711.1 332296789 10578603 complement(145174..146958) 1 NC_015500.1 COGs: COG2407 L-fucose isomerase and related protein; HAMAP: L-fucose isomerase; InterPro IPR012888:IPR012889:IPR015888:IPR005763; KEGG: cpe:CPE0318 L-fucose isomerase; PFAM: L-fucose isomerase, N-terminal-1; L-fucose isomerase, N-terminal-2; L-fucose isomerase-like, C-terminal; PRIAM: L-fucose isomerase; SPTR: L-fucose isomerase 1; TIGRFAM: L-fucose isomerase; IMG reference gene:2504918991; PFAM: L-fucose isomerase, C-terminal domain; L-fucose isomerase, first N-terminal domain; L-fucose isomerase, second N-terminal domain; TIGRFAM: L-fucose isomerase; L-fucose isomerase 146958 10578603 Trebr_0126 Treponema brennaborense DSM 12168 L-fucose isomerase YP_004438711.1 145174 R 906968 CDS YP_004438712.1 332296790 10578604 complement(147166..148602) 1 NC_015500.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: cpf:CPF_1049 L-fuculokinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Rhamnulokinase; SPTR: Carbohydrate kinase, FGGY family protein; IMG reference gene:2504918992; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; Rhamnulokinase 148602 10578604 Trebr_0127 Treponema brennaborense DSM 12168 Rhamnulokinase YP_004438712.1 147166 R 906968 CDS YP_004438713.1 332296791 10578605 complement(148712..149416) 1 NC_015500.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cpf:CPF_1051 L-fuculose phosphate aldolase; PFAM: Class II aldolase/adducin, N-terminal; PRIAM: L-fuculose-phosphate aldolase; SPTR: L-fuculose phosphate aldolase; IMG reference gene:2504918993; PFAM: Class II Aldolase and Adducin N-terminal domain; L-fuculose-phosphate aldolase 149416 10578605 Trebr_0128 Treponema brennaborense DSM 12168 L-fuculose-phosphate aldolase YP_004438713.1 148712 R 906968 CDS YP_004438714.1 332296792 10578606 149567..150433 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: ccb:Clocel_1498 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504918994; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 150433 10578606 Trebr_0129 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004438714.1 149567 D 906968 CDS YP_004438715.1 332296793 10578607 150721..151176 1 NC_015500.1 COGs: COG4154 Fucose dissimilation pathway protein FucU; InterPro IPR007721; KEGG: tra:Trad_2112 RbsD or FucU transport; PFAM: RbsD/FucU transport; SPTR: RbsD or FucU transport; IMG reference gene:2504918995; PFAM: RbsD / FucU transport protein family; transport protein RbsD/FucU 151176 10578607 Trebr_0130 Treponema brennaborense DSM 12168 transport protein RbsD/FucU YP_004438715.1 150721 D 906968 CDS YP_004438716.1 332296794 10578608 151359..152438 1 NC_015500.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: str:Sterm_1702 galactose-binding protein; SPTR: mglB homolog; IMG reference gene:2504918996; galactose-binding protein 152438 10578608 Trebr_0131 Treponema brennaborense DSM 12168 galactose-binding protein YP_004438716.1 151359 D 906968 CDS YP_004438717.1 332296795 10578609 152591..154093 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: pjd:Pjdr2_4330 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504918997; PFAM: ABC transporter; monosaccharide-transporting ATPase 154093 10578609 Trebr_0132 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004438717.1 152591 D 906968 CDS YP_004438718.1 332296796 10578610 154118..155116 1 NC_015500.1 COGs: COG4211 ABC-type glucose/galactose transport system permease component; InterPro IPR001851; KEGG: str:Sterm_4009 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: sugar ABC transporter (Permease); IMG reference gene:2504918998; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 155116 10578610 Trebr_0133 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438718.1 154118 D 906968 CDS YP_004438719.1 332296797 10578611 155148..156131 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ttr:Tter_2385 transcriptional regulator, LacI family; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504918999; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 156131 10578611 Trebr_0134 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004438719.1 155148 D 906968 CDS YP_004438720.1 332296798 10578612 complement(156424..156798) 1 NC_015500.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR015358; KEGG: elm:ELI_1032 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; Transcription regulator MerR, DNA binding; SMART: HTH transcriptional regulator, MerR; SPTR: uncharacterized protein; IMG reference gene:2504919000; PFAM: MerR, DNA binding; MerR family regulatory protein; MerR family transcriptional regulator 156798 10578612 Trebr_0135 Treponema brennaborense DSM 12168 MerR family transcriptional regulator YP_004438720.1 156424 R 906968 CDS YP_004438721.1 332296799 10578613 complement(157120..158895) 1 NC_015500.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005475:IPR005476; KEGG: cac:CA_P0106 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SPTR: 1-deoxyxylulose-5-phosphate synthase, dehydrogenase; IMG reference gene:2504919001; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 158895 10578613 Trebr_0136 Treponema brennaborense DSM 12168 1-deoxy-D-xylulose-5-phosphate synthase YP_004438721.1 157120 R 906968 CDS YP_004438722.1 332296800 10578614 159199..160206 1 NC_015500.1 COGs: COG2768 Uncharacterized Fe-S center protein; KEGG: pdi:BDI_0351 uncharacterized Fe-S center protein, ferredoxin; SPTR: uncharacterized protein; IMG reference gene:2504919002; Fe-S protein 160206 10578614 Trebr_0137 Treponema brennaborense DSM 12168 Fe-S protein YP_004438722.1 159199 D 906968 CDS YP_004438723.1 332296801 10578615 160218..161213 1 NC_015500.1 COGs: COG0701 permease; InterPro IPR005524; KEGG: mac:MA0366 hypothetical protein; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: uncharacterized protein; IMG reference gene:2504919003; PFAM: Predicted permease; hypothetical protein 161213 10578615 Trebr_0138 Treponema brennaborense DSM 12168 hypothetical protein YP_004438723.1 160218 D 906968 CDS YP_004438724.1 332296802 10578616 complement(161314..162510) 1 NC_015500.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; KEGG: eel:EUBELI_01747 solute carrier family 1 (glial high affinity glutamate transporter), member 2; SPTR: uncharacterized protein; IMG reference gene:2504919004; PFAM: Sodium:dicarboxylate symporter family; solute carrier family 1 (glial high affinity glutamate transporter), member 2 162510 10578616 Trebr_0139 Treponema brennaborense DSM 12168 solute carrier family 1 (glial high affinity glutamate transporter), member 2 YP_004438724.1 161314 R 906968 CDS YP_004438725.1 332296803 10578617 complement(162637..163926) 1 NC_015500.1 COGs: COG3681 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0597; InterPro IPR010469; KEGG: csh:Closa_0439 protein of unknown function DUF1063; SPTR: UPF0597 protein CLOBOL_05336; IMG reference gene:2504919005; PFAM: Serine dehydratase alpha chain; hypothetical protein 163926 10578617 Trebr_0140 Treponema brennaborense DSM 12168 hypothetical protein YP_004438725.1 162637 R 906968 CDS YP_004438726.1 332296804 10578618 164198..165094 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: csh:Closa_0440 transcriptional regulator, LysR family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504919006; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator 165094 10578618 Trebr_0141 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004438726.1 164198 D 906968 CDS YP_004438727.1 332296805 10578619 165191..166279 1 NC_015500.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: gur:Gura_2939 30S ribosomal protein S1; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: SSU ribosomal protein S1P; IMG reference gene:2504919007; PFAM: S1 RNA binding domain; RNA binding S1 domain-containing protein 166279 10578619 Trebr_0142 Treponema brennaborense DSM 12168 RNA binding S1 domain-containing protein YP_004438727.1 165191 D 906968 CDS YP_004438728.1 332296806 10578620 166509..167342 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005:IPR010499; KEGG: csh:Closa_1152 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; Bacterial transcription activator, effector binding; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504919008; PFAM: Bacterial transcription activator, effector binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 167342 10578620 Trebr_0143 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004438728.1 166509 D 906968 CDS YP_004438729.1 332296807 10578622 complement(168041..168508) 1 NC_015500.1 KEGG: cdl:CDR20291_0527 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919010; hypothetical protein 168508 10578622 Trebr_0145 Treponema brennaborense DSM 12168 hypothetical protein YP_004438729.1 168041 R 906968 CDS YP_004438730.1 332296808 10578623 complement(168585..168914) 1 NC_015500.1 COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: tde:TDE2247 PemK family protein; PFAM: PemK-like protein; SPTR: PemK family protein; IMG reference gene:2504919011; PFAM: PemK-like protein; transcriptional modulator of MazE/toxin MazF 168914 10578623 Trebr_0146 Treponema brennaborense DSM 12168 transcriptional modulator of MazE/toxin MazF YP_004438730.1 168585 R 906968 CDS YP_004438731.1 332296809 10578624 complement(168902..169150) 1 NC_015500.1 InterPro IPR007159; KEGG: ssm:Spirs_0703 transcriptional regulator/antitoxin, MazE; PFAM: Transcription regulator AbrB/SpoV, predicted; SPTR: Transcriptional regulator/antitoxin, MazE; IMG reference gene:2504919012; PFAM: SpoVT / AbrB like domain; SpoVT/AbrB domain-containing protein 169150 10578624 Trebr_0147 Treponema brennaborense DSM 12168 SpoVT/AbrB domain-containing protein YP_004438731.1 168902 R 906968 CDS YP_004438732.1 332296810 10578625 169366..170496 1 NC_015500.1 COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR003346; KEGG: bpb:bpr_IV010 IS110 family transposase; PFAM: Transposase, IS116/IS110/IS902; SPTR: ISCps8, transposase; IMG reference gene:2504919013; PFAM: Transposase IS116/IS110/IS902 family; Transposase; transposase IS116/IS110/IS902 family protein 170496 10578625 Trebr_0148 Treponema brennaborense DSM 12168 transposase IS116/IS110/IS902 family protein YP_004438732.1 169366 D 906968 CDS YP_004438733.1 332296811 10578626 complement(170766..171509) 1 NC_015500.1 InterPro IPR011528:IPR013498; KEGG: zpr:ZPR_4418 hypothetical membrane protein; PFAM: NERD; DNA topoisomerase, type IA, zn finger; SPTR: Hypothetical membrane protein; IMG reference gene:2504919014; PFAM: Nuclease-related domain; Topoisomerase DNA binding C4 zinc finger; NERD domain-containing protein 171509 10578626 Trebr_0149 Treponema brennaborense DSM 12168 NERD domain-containing protein YP_004438733.1 170766 R 906968 CDS YP_004438734.1 332296812 10578627 complement(171510..171962) 1 NC_015500.1 IMG reference gene:2504919015; hypothetical protein 171962 10578627 Trebr_0150 Treponema brennaborense DSM 12168 hypothetical protein YP_004438734.1 171510 R 906968 CDS YP_004438735.1 332296813 10578628 complement(172260..172481) 1 NC_015500.1 InterPro IPR012545; KEGG: csh:Closa_3141 protein of unknown function DUF1697; PFAM: Protein of unknown function DUF1697; SPTR: uncharacterized protein; IMG reference gene:2504919016; PFAM: Protein of unknown function (DUF1697); hypothetical protein 172481 10578628 Trebr_0151 Treponema brennaborense DSM 12168 hypothetical protein YP_004438735.1 172260 R 906968 CDS YP_004438736.1 332296814 10578630 173407..174729 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: csh:Closa_1153 multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919018; PFAM: MatE; TIGRFAM: efflux protein, MATE family; multi antimicrobial extrusion protein MatE 174729 10578630 Trebr_0153 Treponema brennaborense DSM 12168 multi antimicrobial extrusion protein MatE YP_004438736.1 173407 D 906968 CDS YP_004438737.1 332296815 10578631 complement(174905..175804) 1 NC_015500.1 InterPro IPR013216; KEGG: bth:BT_2972 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: SAM-dependent methyltransferase; IMG reference gene:2504919019; PFAM: Methyltransferase domain; type 11 methyltransferase 175804 10578631 Trebr_0154 Treponema brennaborense DSM 12168 type 11 methyltransferase YP_004438737.1 174905 R 906968 CDS YP_004438738.1 332296816 10578632 complement(175929..176210) 1 NC_015500.1 KEGG: cpr:CPR_0719 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919020; hypothetical protein 176210 10578632 Trebr_0155 Treponema brennaborense DSM 12168 hypothetical protein YP_004438738.1 175929 R 906968 CDS YP_004438739.1 332296817 10578634 176739..177431 1 NC_015500.1 COGs: COG1794 Aspartate racemase; InterPro IPR015942:IPR004380; KEGG: cbe:Cbei_3176 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Aspartate racemase; TIGRFAM: Aspartate racemase; IMG reference gene:2504919022; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase; aspartate racemase 177431 10578634 Trebr_0157 Treponema brennaborense DSM 12168 aspartate racemase YP_004438739.1 176739 D 906968 CDS YP_004438740.1 332296818 10578635 complement(177528..177854) 1 NC_015500.1 InterPro IPR007076; KEGG: shi:Shel_09460 regulator of competence-specific genes; PFAM: TfoX, N-terminal; SPTR: TfoX N-terminal domain family protein; IMG reference gene:2504919023; PFAM: TfoX N-terminal domain; TfoX domain-containing protein 177854 10578635 Trebr_0158 Treponema brennaborense DSM 12168 TfoX domain-containing protein YP_004438740.1 177528 R 906968 CDS YP_004438741.1 332296819 10578636 complement(177872..178237) 1 NC_015500.1 KEGG: ccb:Clocel_2348 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919024; hypothetical protein 178237 10578636 Trebr_0159 Treponema brennaborense DSM 12168 hypothetical protein YP_004438741.1 177872 R 906968 CDS YP_004438742.1 332296820 10578637 178536..178820 1 NC_015500.1 KEGG: cce:Ccel_2739 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919025; hypothetical protein 178820 10578637 Trebr_0160 Treponema brennaborense DSM 12168 hypothetical protein YP_004438742.1 178536 D 906968 CDS YP_004438743.1 332296821 10578638 complement(178826..179698) 1 NC_015500.1 InterPro IPR000182; KEGG: bpb:bpr_I0998 GNAT family acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase GNAT family; IMG reference gene:2504919026; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 179698 10578638 Trebr_0161 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004438743.1 178826 R 906968 CDS YP_004438744.1 332296822 10578639 complement(179736..180848) 1 NC_015500.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR001450; KEGG: cbe:Cbei_4835 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2504919027; PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF362); 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 180848 10578639 Trebr_0162 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004438744.1 179736 R 906968 CDS YP_004438745.1 332296823 10578640 complement(180891..182651) 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: sus:Acid_1102 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504919028; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 182651 10578640 Trebr_0163 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004438745.1 180891 R 906968 CDS YP_004438746.1 332296824 10578641 182825..183253 1 NC_015500.1 IMG reference gene:2504919029; hypothetical protein 183253 10578641 Trebr_0164 Treponema brennaborense DSM 12168 hypothetical protein YP_004438746.1 182825 D 906968 CDS YP_004438747.1 332296825 10578642 complement(183386..184102) 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: aba:Acid345_3061 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504919030; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; two component transcriptional regulator, winged helix family 184102 10578642 Trebr_0165 Treponema brennaborense DSM 12168 two component transcriptional regulator, winged helix family YP_004438747.1 183386 R 906968 CDS YP_004438748.1 332296826 10578643 complement(184107..185417) 1 NC_015500.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: amt:Amet_3781 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2504919031; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 185417 10578643 Trebr_0166 Treponema brennaborense DSM 12168 major facilitator superfamily protein YP_004438748.1 184107 R 906968 CDS YP_004438749.1 332296827 10578644 complement(185458..187332) 1 NC_015500.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: ssm:Spirs_1696 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Multi-sensor signal transduction histidine kinase; IMG reference gene:2504919032; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 187332 10578644 Trebr_0167 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004438749.1 185458 R 906968 CDS YP_004438750.1 332296828 10578645 complement(187319..188065) 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: sta:STHERM_c05370 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Transcriptional regulatory protein; IMG reference gene:2504919033; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; two component transcriptional regulator, winged helix family 188065 10578645 Trebr_0168 Treponema brennaborense DSM 12168 two component transcriptional regulator, winged helix family YP_004438750.1 187319 R 906968 CDS YP_004438751.1 332296829 10578646 188409..189278 1 NC_015500.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR006059:IPR011862; KEGG: ssm:Spirs_1702 phosphate binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Phosphate binding protein; TIGRFAM: Phosphate binding protein; IMG reference gene:2504919034; TIGRFAM: phosphate binding protein; phosphate binding protein 189278 10578646 Trebr_0169 Treponema brennaborense DSM 12168 phosphate binding protein YP_004438751.1 188409 D 906968 CDS YP_004438752.1 332296830 10578647 189474..190628 1 NC_015500.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: bpb:bpr_I2638 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504919035; PFAM: Radical SAM superfamily; Radical SAM domain protein 190628 10578647 Trebr_0170 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004438752.1 189474 D 906968 CDS YP_004438753.1 332296831 10578648 190625..191359 1 NC_015500.1 InterPro IPR001647; KEGG: cpy:Cphy_1864 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: uncharacterized protein; IMG reference gene:2504919036; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 191359 10578648 Trebr_0171 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004438753.1 190625 D 906968 CDS YP_004438754.1 332296832 10578649 complement(191344..191814) 1 NC_015500.1 COGs: COG2193 Bacterioferritin (cytochrome b1); InterPro IPR008331:IPR002024; KEGG: gme:Gmet_1908 bacterioferritin; PFAM: Ferritin/Dps protein; SPTR: Bacterioferritin; TIGRFAM: Bacterioferritin; IMG reference gene:2504919037; PFAM: Ferritin-like domain; TIGRFAM: bacterioferritin; bacterioferritin 191814 10578649 Trebr_0172 Treponema brennaborense DSM 12168 bacterioferritin YP_004438754.1 191344 R 906968 CDS YP_004438755.1 332296833 10578650 192019..192921 1 NC_015500.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR011864; KEGG: ssm:Spirs_1701 phosphate ABC transporter, inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; IMG reference gene:2504919038; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; phosphate ABC transporter permease 192921 10578650 Trebr_0173 Treponema brennaborense DSM 12168 phosphate ABC transporter permease YP_004438755.1 192019 D 906968 CDS YP_004438756.1 332296834 10578651 192921..194600 1 NC_015500.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: ssm:Spirs_1700 phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: Phosphate transport system permease protein 2; IMG reference gene:2504919039; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA; phosphate ABC transporter permease 194600 10578651 Trebr_0174 Treponema brennaborense DSM 12168 phosphate ABC transporter permease YP_004438756.1 192921 D 906968 CDS YP_004438757.1 332296835 10578652 194657..195496 1 NC_015500.1 COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: cce:Ccel_0197 protein of unknown function DUF1113; PFAM: Protein of unknown function DUF1113; SPTR: uncharacterized protein; IMG reference gene:2504919040; PFAM: Protein of unknown function (DUF1113); hypothetical protein 195496 10578652 Trebr_0175 Treponema brennaborense DSM 12168 hypothetical protein YP_004438757.1 194657 D 906968 CDS YP_004438758.1 332296836 10578653 complement(195555..196427) 1 NC_015500.1 KEGG: bpo:BP951000_1114 hypothetical protein; IMG reference gene:2504919041; hypothetical protein 196427 10578653 Trebr_0176 Treponema brennaborense DSM 12168 hypothetical protein YP_004438758.1 195555 R 906968 CDS YP_004438759.1 332296837 10578654 196476..197051 1 NC_015500.1 KEGG: alv:Alvin_1609 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919042; hypothetical protein 197051 10578654 Trebr_0177 Treponema brennaborense DSM 12168 hypothetical protein YP_004438759.1 196476 D 906968 CDS YP_004438760.1 332296838 10578655 complement(197138..198172) 1 NC_015500.1 COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: ppy:PPE_04154 threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; SPTR: uncharacterized protein; IMG reference gene:2504919043; PFAM: Beta-eliminating lyase; aromatic amino acid beta-eliminating lyase/threonine aldolase 198172 10578655 Trebr_0178 Treponema brennaborense DSM 12168 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_004438760.1 197138 R 906968 CDS YP_004438761.1 332296839 10578656 complement(198169..198819) 1 NC_015500.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: lcz:LCAZH_1420 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; IMG reference gene:2504919044; PFAM: Imidazoleglycerol-phosphate dehydratase; imidazoleglycerol-phosphate dehydratase 198819 10578656 Trebr_0179 Treponema brennaborense DSM 12168 imidazoleglycerol-phosphate dehydratase YP_004438761.1 198169 R 906968 CDS YP_004438762.1 332296840 10578657 complement(198844..199698) 1 NC_015500.1 COGs: COG0040 ATP phosphoribosyltransferase; HAMAP: Histidine biosynthesis HisG, ATP phosphoribosyltransferase, subgroup; InterPro IPR013820:IPR013115:IPR020621; KEGG: kko:Kkor_0854 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase, catalytic region; Histidine biosynthesis HisG, C-terminal; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, catalytic region; Histidine biosynthesis HisG, C-terminal; IMG reference gene:2504919045; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase; ATP phosphoribosyltransferase 199698 10578657 Trebr_0180 Treponema brennaborense DSM 12168 ATP phosphoribosyltransferase YP_004438762.1 198844 R 906968 CDS YP_004438763.1 332296841 10578658 200203..201390 1 NC_015500.1 COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: cdf:CD0657 Na(+)/H(+) antiporter; PFAM: Cation/H+ exchanger; SPTR: uncharacterized protein; IMG reference gene:2504919046; PFAM: Sodium/hydrogen exchanger family; sodium/hydrogen exchanger 201390 10578658 Trebr_0181 Treponema brennaborense DSM 12168 sodium/hydrogen exchanger YP_004438763.1 200203 D 906968 CDS YP_004438764.1 332296842 10578659 complement(201540..202538) 1 NC_015500.1 InterPro IPR002790; KEGG: ssm:Spirs_3345 hypothetical protein; PFAM: Protein of unknown function DUF88; SPTR: uncharacterized protein; IMG reference gene:2504919047; PFAM: Protein of unknown function DUF88; hypothetical protein 202538 10578659 Trebr_0182 Treponema brennaborense DSM 12168 hypothetical protein YP_004438764.1 201540 R 906968 CDS YP_004438765.1 332296843 10578660 complement(202601..203233) 1 NC_015500.1 InterPro IPR019734:IPR001440; KEGG: psl:Psta_3609 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504919048; PFAM: Tetratricopeptide repeat; hypothetical protein 203233 10578660 Trebr_0183 Treponema brennaborense DSM 12168 hypothetical protein YP_004438765.1 202601 R 906968 CDS YP_004438766.1 332296844 10578661 203553..205403 1 NC_015500.1 InterPro IPR000421; KEGG: sta:STHERM_c15300 hypothetical protein; PFAM: Coagulation factor 5/8 type, C-terminal; SMART: Coagulation factor 5/8 type, C-terminal; SPTR: uncharacterized protein; IMG reference gene:2504919049; PFAM: F5/8 type C domain; Glycosyl hydrolase family 71; coagulation factor 5/8 type domain-containing protein 205403 10578661 Trebr_0184 Treponema brennaborense DSM 12168 coagulation factor 5/8 type domain-containing protein YP_004438766.1 203553 D 906968 CDS YP_004438767.1 332296845 10578662 205616..206347 1 NC_015500.1 KEGG: sta:STHERM_c15290 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919050; hypothetical protein 206347 10578662 Trebr_0185 Treponema brennaborense DSM 12168 hypothetical protein YP_004438767.1 205616 D 906968 CDS YP_004438768.1 332296846 10578663 206419..207894 1 NC_015500.1 KEGG: sta:STHERM_c15280 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919051; hypothetical protein 207894 10578663 Trebr_0186 Treponema brennaborense DSM 12168 hypothetical protein YP_004438768.1 206419 D 906968 CDS YP_004438769.1 332296847 10578664 207929..209320 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c15360 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein; IMG reference gene:2504919052; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 209320 10578664 Trebr_0187 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438769.1 207929 D 906968 CDS YP_004438770.1 332296848 10578665 209497..210369 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c15350 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Transporter; IMG reference gene:2504919053; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 210369 10578665 Trebr_0188 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438770.1 209497 D 906968 CDS YP_004438771.1 332296849 10578666 210382..211263 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c15340 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family; IMG reference gene:2504919054; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 211263 10578666 Trebr_0189 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438771.1 210382 D 906968 CDS YP_004438772.1 332296850 10578667 211281..213638 1 NC_015500.1 COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194; KEGG: sta:STHERM_c15330 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; Glycoside hydrolase, family 65, C-terminal; PRIAM: Kojibiose phosphorylase; SPTR: Kojibiose phosphorylase; IMG reference gene:2504919055; PFAM: Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; Kojibiose phosphorylase 213638 10578667 Trebr_0190 Treponema brennaborense DSM 12168 Kojibiose phosphorylase YP_004438772.1 211281 D 906968 CDS YP_004438773.1 332296851 10578668 213635..215995 1 NC_015500.1 COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195; KEGG: sta:STHERM_c15320 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; PRIAM: Kojibiose phosphorylase; SPTR: Glycoside hydrolase family 65 central catalytic; IMG reference gene:2504919056; PFAM: Glycosyl hydrolase family 65, N-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Kojibiose phosphorylase 215995 10578668 Trebr_0191 Treponema brennaborense DSM 12168 Kojibiose phosphorylase YP_004438773.1 213635 D 906968 CDS YP_004438774.1 332296852 10578669 215983..216618 1 NC_015500.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR010972:IPR010976:IPR006402; KEGG: sta:STHERM_c15310 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Beta-phosphoglucomutase; SPTR: uncharacterized protein; TIGRFAM: Beta-phosphoglucomutase; Beta-phosphoglucomutase hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504919057; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase 216618 10578669 Trebr_0192 Treponema brennaborense DSM 12168 beta-phosphoglucomutase YP_004438774.1 215983 D 906968 CDS YP_004438775.1 332296853 10578670 complement(216643..217659) 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cpy:Cphy_3312 LacI family transcription regulator; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504919058; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 217659 10578670 Trebr_0193 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004438775.1 216643 R 906968 CDS YP_004438776.1 332296854 10578671 217938..218306 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: dno:DNO_0868 two-component response regulator; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: uncharacterized protein; IMG reference gene:2504919059; PFAM: Response regulator receiver domain; response regulator receiver protein 218306 10578671 Trebr_0194 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004438776.1 217938 D 906968 CDS YP_004438777.1 332296855 10578672 218475..218921 1 NC_015500.1 KEGG: sta:STHERM_c03610 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919060; hypothetical protein 218921 10578672 Trebr_0195 Treponema brennaborense DSM 12168 hypothetical protein YP_004438777.1 218475 D 906968 CDS YP_004438778.1 332296856 10578673 218937..221714 1 NC_015500.1 COGs: COG0004 Ammonia permease; InterPro IPR003594:IPR001905:IPR008207; KEGG: sta:STHERM_c03600 ammonia permease with sensory box/GGDEF domains; PFAM: Ammonium transporter; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Probable ammonia permease with sensory box/GGDEF domains; TIGRFAM: Ammonium transporter; IMG reference gene:2504919061; PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter; multi-sensor signal transduction histidine kinase 221714 10578673 Trebr_0196 Treponema brennaborense DSM 12168 multi-sensor signal transduction histidine kinase YP_004438778.1 218937 D 906968 CDS YP_004438779.1 332296857 10578674 complement(222228..223112) 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: bmq:BMQ_3743 transcriptional regulator, LysR family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504919062; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator 223112 10578674 Trebr_0197 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004438779.1 222228 R 906968 CDS YP_004438780.1 332296858 10578675 complement(223265..224119) 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: afn:Acfer_0523 transcriptional regulator, LysR family; PFAM: HTH transcriptional regulator, LysR; LysR, substrate-binding; SPTR: Transcriptional regulator; IMG reference gene:2504919063; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; LysR family transcriptional regulator 224119 10578675 Trebr_0198 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004438780.1 223265 R 906968 CDS YP_004438781.1 332296859 10578676 complement(224208..224687) 1 NC_015500.1 InterPro IPR000182; KEGG: csh:Closa_3290 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919064; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 224687 10578676 Trebr_0199 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004438781.1 224208 R 906968 CDS YP_004438782.1 332296860 10578677 complement(225064..226098) 1 NC_015500.1 COGs: COG3274 conserved hypothetical protein; InterPro IPR002656; KEGG: ssm:Spirs_0710 hypothetical protein; PFAM: Acyltransferase 3; SPTR: uncharacterized protein; IMG reference gene:2504919065; PFAM: Acyltransferase family; acyltransferase 3 226098 10578677 Trebr_0200 Treponema brennaborense DSM 12168 acyltransferase 3 YP_004438782.1 225064 R 906968 CDS YP_004438783.1 332296861 10578678 226268..226612 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE2445 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504919066; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 226612 10578678 Trebr_0201 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004438783.1 226268 D 906968 CDS YP_004438784.1 332296862 10578679 complement(226650..227210) 1 NC_015500.1 KEGG: str:Sterm_3350 protein of unknown function DUF419; SPTR: uncharacterized protein; IMG reference gene:2504919067; hypothetical protein 227210 10578679 Trebr_0202 Treponema brennaborense DSM 12168 hypothetical protein YP_004438784.1 226650 R 906968 CDS YP_004438785.1 332296863 10578680 227677..228543 1 NC_015500.1 COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395; KEGG: ccb:Clocel_1467 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: uncharacterized protein; IMG reference gene:2504919068; PFAM: Aldo/keto reductase family; 2,5-didehydrogluconate reductase 228543 10578680 Trebr_0203 Treponema brennaborense DSM 12168 2,5-didehydrogluconate reductase YP_004438785.1 227677 D 906968 CDS YP_004438786.1 332296864 10578681 228688..229245 1 NC_015500.1 KEGG: ccv:CCV52592_1956 flavodoxin; SPTR: uncharacterized protein; IMG reference gene:2504919069; flavodoxin 229245 10578681 Trebr_0204 Treponema brennaborense DSM 12168 flavodoxin YP_004438786.1 228688 D 906968 CDS YP_004438787.1 332296865 10578683 229934..230449 1 NC_015500.1 KEGG: afn:Acfer_0531 flavodoxin; SPTR: uncharacterized protein; IMG reference gene:2504919071; PFAM: NADPH-dependent FMN reductase; flavodoxin 230449 10578683 Trebr_0206 Treponema brennaborense DSM 12168 flavodoxin YP_004438787.1 229934 D 906968 CDS YP_004438788.1 332296866 10578684 230484..230954 1 NC_015500.1 KEGG: tde:TDE0356 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504919072; hypothetical protein 230954 10578684 Trebr_0207 Treponema brennaborense DSM 12168 hypothetical protein YP_004438788.1 230484 D 906968 CDS YP_004438789.1 332296867 10578685 231117..231650 1 NC_015500.1 KEGG: hhe:HH1031 flavodoxin; SPTR: Flavodoxin; IMG reference gene:2504919073; PFAM: Flavodoxin-like fold; flavodoxin 231650 10578685 Trebr_0208 Treponema brennaborense DSM 12168 flavodoxin YP_004438789.1 231117 D 906968 CDS YP_004438790.1 332296868 10578686 231647..232612 1 NC_015500.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: ttm:Tthe_0870 aldo/keto reductase; PFAM: Aldo/keto reductase; PRIAM: Aryl-alcohol dehydrogenase (NADP(+)); SPTR: Aldo/keto reductase; IMG reference gene:2504919074; PFAM: Aldo/keto reductase family; aryl-alcohol dehydrogenase 232612 10578686 Trebr_0209 Treponema brennaborense DSM 12168 aryl-alcohol dehydrogenase YP_004438790.1 231647 D 906968 CDS YP_004438791.1 332296869 10578687 232710..233297 1 NC_015500.1 KEGG: fsu:Fisuc_1693 protein of unknown function DUF323; SPTR: Conserved domain protein; IMG reference gene:2504919075; PFAM: Flavodoxin-like fold; hypothetical protein 233297 10578687 Trebr_0210 Treponema brennaborense DSM 12168 hypothetical protein YP_004438791.1 232710 D 906968 CDS YP_004438792.1 332296870 10578688 233340..234233 1 NC_015500.1 COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: fsu:Fisuc_1693 protein of unknown function DUF323; PFAM: Sulphatase-modifying factor; SPTR: Serine/threonine-protein kinase Pkn1; IMG reference gene:2504919076; PFAM: Formylglycine-generating sulfatase enzyme; sulfatase-modifying factor protein 234233 10578688 Trebr_0211 Treponema brennaborense DSM 12168 sulfatase-modifying factor protein YP_004438792.1 233340 D 906968 CDS YP_004438793.1 332296871 10578689 234246..234386 1 NC_015500.1 IMG reference gene:2504919077; hypothetical protein 234386 10578689 Trebr_0212 Treponema brennaborense DSM 12168 hypothetical protein YP_004438793.1 234246 D 906968 CDS YP_004438794.1 332296872 10578690 234383..235045 1 NC_015500.1 KEGG: fsu:Fisuc_1692 Holliday junction ATP-dependent DNA helicase RuvA; SPTR: Holliday junction ATP-dependent DNA helicase RuvA; IMG reference gene:2504919078; Holliday junction ATP-dependent DNA helicase RuvA 235045 10578690 Trebr_0213 Treponema brennaborense DSM 12168 Holliday junction ATP-dependent DNA helicase RuvA YP_004438794.1 234383 D 906968 CDS YP_004438795.1 332296873 10578691 235309..235518 1 NC_015500.1 IMG reference gene:2504919079; hypothetical protein 235518 10578691 Trebr_0214 Treponema brennaborense DSM 12168 hypothetical protein YP_004438795.1 235309 D 906968 CDS YP_004438796.1 332296874 10578692 235786..237036 1 NC_015500.1 InterPro IPR001647; KEGG: ssm:Spirs_0035 transcriptional regulator, TetR family; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504919080; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 237036 10578692 Trebr_0215 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004438796.1 235786 D 906968 CDS YP_004438797.1 332296875 10578693 237178..238554 1 NC_015500.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ssm:Spirs_0036 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; IMG reference gene:2504919081; PFAM: Outer membrane efflux protein; outer membrane efflux protein 238554 10578693 Trebr_0216 Treponema brennaborense DSM 12168 outer membrane efflux protein YP_004438797.1 237178 D 906968 CDS YP_004438798.1 332296876 10578694 238567..239496 1 NC_015500.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: ssm:Spirs_0037 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504919082; TIGRFAM: RND family efflux transporter, MFP subunit; RND family efflux transporter MFP subunit 239496 10578694 Trebr_0217 Treponema brennaborense DSM 12168 RND family efflux transporter MFP subunit YP_004438798.1 238567 D 906968 CDS YP_004438799.1 332296877 10578695 239497..242814 1 NC_015500.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: ssm:Spirs_0038 acriflavin resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; IMG reference gene:2504919083; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; acriflavin resistance protein 242814 10578695 Trebr_0218 Treponema brennaborense DSM 12168 acriflavin resistance protein YP_004438799.1 239497 D 906968 CDS YP_004438800.1 332296878 10578696 242804..243187 1 NC_015500.1 KEGG: sta:STHERM_c21680 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919084; hypothetical protein 243187 10578696 Trebr_0219 Treponema brennaborense DSM 12168 hypothetical protein YP_004438800.1 242804 D 906968 CDS YP_004438801.1 332296879 10578697 243369..245282 1 NC_015500.1 KEGG: ccb:Clocel_3315 regulator of chromosome condensation RCC1; SPTR: Regulator of chromosome condensation RCC1; IMG reference gene:2504919085; hypothetical protein 245282 10578697 Trebr_0220 Treponema brennaborense DSM 12168 hypothetical protein YP_004438801.1 243369 D 906968 CDS YP_004438802.1 332296880 10578698 complement(245382..248243) 1 NC_015500.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dfe:Dfer_4913 peptidase M16 domain protein; PFAM: Peptidase M16, N-terminal; Peptidase M16, C-terminal; SPTR: Peptidase M16 domain protein; IMG reference gene:2504919086; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); peptidase M16 domain-containing protein 248243 10578698 Trebr_0221 Treponema brennaborense DSM 12168 peptidase M16 domain-containing protein YP_004438802.1 245382 R 906968 CDS YP_004438803.1 332296881 10578699 248409..248918 1 NC_015500.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; KEGG: ckr:CKR_2518 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919087; PFAM: Flavin reductase like domain; hypothetical protein 248918 10578699 Trebr_0222 Treponema brennaborense DSM 12168 hypothetical protein YP_004438803.1 248409 D 906968 CDS YP_004438804.1 332296882 10578700 248984..250726 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ipo:Ilyop_1313 ABC transporter related protein; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; manually curated; IMG reference gene:2504919088; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 250726 10578700 Trebr_0223 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004438804.1 248984 D 906968 CDS YP_004438805.1 332296883 10578701 complement(251029..252789) 1 NC_015500.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: glo:Glov_2441 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; TIGRFAM: ATP-binding cassette protein, ChvD family; IMG reference gene:2504919089; PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family; ChvD family ATP-binding protein 252789 10578701 Trebr_0224 Treponema brennaborense DSM 12168 ChvD family ATP-binding protein YP_004438805.1 251029 R 906968 CDS YP_004438806.1 332296884 10578702 complement(252949..253371) 1 NC_015500.1 IMG reference gene:2504919090; hypothetical protein 253371 10578702 Trebr_0225 Treponema brennaborense DSM 12168 hypothetical protein YP_004438806.1 252949 R 906968 CDS YP_004438807.1 332296885 10578703 complement(253469..253975) 1 NC_015500.1 InterPro IPR019223; KEGG: tde:TDE1857 hypothetical protein; PFAM: Protein of unknown function DUF2147; SPTR: uncharacterized protein; IMG reference gene:2504919091; PFAM: Uncharacterized protein conserved in bacteria (DUF2147); hypothetical protein 253975 10578703 Trebr_0226 Treponema brennaborense DSM 12168 hypothetical protein YP_004438807.1 253469 R 906968 CDS YP_004438808.1 332296886 10578704 complement(253995..256172) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: ssm:Spirs_3246 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504919092; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 256172 10578704 Trebr_0227 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004438808.1 253995 R 906968 CDS YP_004438809.1 332296887 10578705 complement(256337..257098) 1 NC_015500.1 KEGG: tde:TDE0098 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504919093; PFAM: Protein of unknown function (DUF3298); hypothetical protein 257098 10578705 Trebr_0228 Treponema brennaborense DSM 12168 hypothetical protein YP_004438809.1 256337 R 906968 CDS YP_004438810.1 332296888 10578706 257291..257521 1 NC_015500.1 COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: ssm:Spirs_4302 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: NifU-like protein; IMG reference gene:2504919094; PFAM: NifU-like domain; nitrogen-fixing NifU domain-containing protein 257521 10578706 Trebr_0229 Treponema brennaborense DSM 12168 nitrogen-fixing NifU domain-containing protein YP_004438810.1 257291 D 906968 CDS YP_004438811.1 332296889 10578707 257554..258105 1 NC_015500.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: tde:TDE1925 peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504919095; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Peptidylprolyl isomerase 258105 10578707 Trebr_0230 Treponema brennaborense DSM 12168 Peptidylprolyl isomerase YP_004438811.1 257554 D 906968 CDS YP_004438812.1 332296890 10578708 complement(258123..258737) 1 NC_015500.1 COGs: COG0703 Shikimate kinase; HAMAP: Shikimate kinase; InterPro IPR000623; KEGG: sta:STHERM_c05910 shikimate kinase; PFAM: Shikimate kinase; SPTR: Shikimate kinase; IMG reference gene:2504919096; PFAM: Shikimate kinase; shikimate kinase 258737 10578708 Trebr_0231 Treponema brennaborense DSM 12168 shikimate kinase YP_004438812.1 258123 R 906968 CDS YP_004438813.1 332296891 10578709 258791..259441 1 NC_015500.1 KEGG: oih:OB1807 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919097; hypothetical protein 259441 10578709 Trebr_0232 Treponema brennaborense DSM 12168 hypothetical protein YP_004438813.1 258791 D 906968 CDS YP_004438814.1 332296892 10578710 complement(259365..261788) 1 NC_015500.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: cdf:CD1841 signaling protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919098; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 261788 10578710 Trebr_0233 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004438814.1 259365 R 906968 CDS YP_004438815.1 332296893 10578711 complement(261865..262512) 1 NC_015500.1 KEGG: clj:CLJU_c26850 hypothetical protein; SPTR: membrane protein; IMG reference gene:2504919099; hypothetical protein 262512 10578711 Trebr_0234 Treponema brennaborense DSM 12168 hypothetical protein YP_004438815.1 261865 R 906968 CDS YP_004438816.1 332296894 10578712 complement(262594..263445) 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: clj:CLJU_c26860 ABC transporter ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504919100; PFAM: ABC transporter; ABC transporter 263445 10578712 Trebr_0235 Treponema brennaborense DSM 12168 ABC transporter YP_004438816.1 262594 R 906968 CDS YP_004438817.1 332296895 10578713 complement(263432..263683) 1 NC_015500.1 InterPro IPR007159:IPR006339; KEGG: dhd:Dhaf_1655 transcriptional regulator, AbrB family; PFAM: Transcription regulator AbrB/SpoV, predicted; SPTR: Transcriptional regulator, AbrB family; TIGRFAM: Transcription regulator AbrB; IMG reference gene:2504919101; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; transcriptional regulator, AbrB family 263683 10578713 Trebr_0236 Treponema brennaborense DSM 12168 transcriptional regulator, AbrB family YP_004438817.1 263432 R 906968 CDS YP_004438818.1 332296896 10578714 complement(263755..264048) 1 NC_015500.1 InterPro IPR018113; KEGG: lgs:LEGAS_0034 PTS system sucrose-specific transporter subunit EIIBC; PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: Phosphotransferase system maltose-specific enzyme IICB component; IMG reference gene:2504919102; PFAM: phosphotransferase system, EIIB; phosphotransferase system EIIB/cysteine, phosphorylation site 264048 10578714 Trebr_0237 Treponema brennaborense DSM 12168 phosphotransferase system EIIB/cysteine, phosphorylation site YP_004438818.1 263755 R 906968 CDS YP_004438819.1 332296897 10578715 complement(264045..265715) 1 NC_015500.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR008731:IPR008279:IPR000121:IPR006318; KEGG: PTS system enzyme I; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile region; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SPTR: Phosphoenolpyruvate--protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; IMG reference gene:2504919103; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; phosphoenolpyruvate-protein phosphotransferase 265715 10578715 Trebr_0238 Treponema brennaborense DSM 12168 phosphoenolpyruvate-protein phosphotransferase YP_004438819.1 264045 R 906968 CDS YP_004438820.1 332296898 10578716 complement(265716..265973) 1 NC_015500.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: cpy:Cphy_1769 phosphotransferase system, phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: uncharacterized protein; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; IMG reference gene:2504919104; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; phosphotransferase system, phosphocarrier protein HPr 265973 10578716 Trebr_0239 Treponema brennaborense DSM 12168 phosphotransferase system, phosphocarrier protein HPr YP_004438820.1 265716 R 906968 CDS YP_004438821.1 332296899 10578717 complement(265978..266820) 1 NC_015500.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR004341:IPR011608; KEGG: bld:BLi04201 LicT; PFAM: CAT RNA-binding region; PRD; SPTR: transcription antiterminator LicT; IMG reference gene:2504919105; PFAM: CAT RNA binding domain; PRD domain; transcriptional antiterminator BglG 266820 10578717 Trebr_0240 Treponema brennaborense DSM 12168 transcriptional antiterminator BglG YP_004438821.1 265978 R 906968 CDS YP_004438822.1 332296900 10578718 complement(266833..268266) 1 NC_015500.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360; KEGG: cbe:Cbei_3271 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 1; PRIAM: 6-phospho-beta-glucosidase; SPTR: 6-phospho-beta-glucosidase; IMG reference gene:2504919106; PFAM: Glycosyl hydrolase family 1; 6-phospho-beta-glucosidase 268266 10578718 Trebr_0241 Treponema brennaborense DSM 12168 6-phospho-beta-glucosidase YP_004438822.1 266833 R 906968 CDS YP_004438823.1 332296901 10578720 complement(270574..271896) 1 NC_015500.1 IMG reference gene:2504919108; hypothetical protein 271896 10578720 Trebr_0243 Treponema brennaborense DSM 12168 hypothetical protein YP_004438823.1 270574 R 906968 CDS YP_004438824.1 332296902 10578721 complement(271962..273443) 1 NC_015500.1 KEGG: bth:BT_3066 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919109; hypothetical protein 273443 10578721 Trebr_0244 Treponema brennaborense DSM 12168 hypothetical protein YP_004438824.1 271962 R 906968 CDS YP_004438825.1 332296903 10578722 complement(273440..274468) 1 NC_015500.1 IMG reference gene:2504919110; hypothetical protein 274468 10578722 Trebr_0245 Treponema brennaborense DSM 12168 hypothetical protein YP_004438825.1 273440 R 906968 CDS YP_004438826.1 332296904 10578723 complement(274585..275160) 1 NC_015500.1 IMG reference gene:2504919111; hypothetical protein 275160 10578723 Trebr_0246 Treponema brennaborense DSM 12168 hypothetical protein YP_004438826.1 274585 R 906968 CDS YP_004438827.1 332296905 10578724 275577..276854 1 NC_015500.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474:IPR000991:IPR006274; KEGG: carbamoyl-phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; IMG reference gene:2504919112; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; carbamoyl-phosphate synthase small subunit 276854 10578724 Trebr_0247 Treponema brennaborense DSM 12168 carbamoyl-phosphate synthase small subunit YP_004438827.1 275577 D 906968 CDS YP_004438828.1 332296906 10578725 276975..281267 1 NC_015500.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); HAMAP: Diaminopimelate epimerase; InterProIPR005481:IPR005479:IPR005480:IPR011607:IPR 001653:IPR006275; KEGG: carbamoyl-phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Diaminopimelate epimerase; PRIAM: Carbamoyl-phosphate synthase (ammonia)., Diaminopimelate epimerase; SPTR: uncharacterized protein; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; Diaminopimelate epimerase; IMG reference gene:2504919113; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; carbamoyl-phosphate synthase, large subunit; diaminopimelate epimerase 281267 10578725 Trebr_0248 Treponema brennaborense DSM 12168 diaminopimelate epimerase YP_004438828.1 276975 D 906968 CDS YP_004438829.1 332296907 10578726 281632..282225 1 NC_015500.1 IMG reference gene:2504919114; hypothetical protein 282225 10578726 Trebr_0249 Treponema brennaborense DSM 12168 hypothetical protein YP_004438829.1 281632 D 906968 CDS YP_004438830.1 332296908 10578727 complement(282418..283596) 1 NC_015500.1 KEGG: elm:ELI_1095 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919115; PFAM: Protein of unknown function (DUF2974); hypothetical protein 283596 10578727 Trebr_0250 Treponema brennaborense DSM 12168 hypothetical protein YP_004438830.1 282418 R 906968 CDS YP_004438831.1 332296909 10578728 complement(283666..284613) 1 NC_015500.1 COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: L-lactate dehydrogenase; InterPro IPR001236:IPR011304; KEGG: tde:TDE0351 L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; PRIAM: L-lactate dehydrogenase; SPTR: L-lactate dehydrogenase; TIGRFAM: L-lactate dehydrogenase; IMG reference gene:2504919116; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase; L-lactate dehydrogenase 284613 10578728 Trebr_0251 Treponema brennaborense DSM 12168 L-lactate dehydrogenase YP_004438831.1 283666 R 906968 CDS YP_004438832.1 332296910 10578729 complement(284780..285925) 1 NC_015500.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: lpp:lpp1170 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919117; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 285925 10578729 Trebr_0252 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004438832.1 284780 R 906968 CDS YP_004438833.1 332296911 10578730 complement(286146..287675) 1 NC_015500.1 COGs: COG0486 GTPase; HAMAP: tRNA modification GTPase TrmE; InterPro IPR018948:IPR002917:IPR004520:IPR005225; KEGG: tde:TDE2180 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE, N-terminal; GTP-binding protein, HSR1-related; SPTR: tRNA modification GTPase TrmE; TIGRFAM: tRNA modification GTPase TrmE; Small GTP-binding protein; IMG reference gene:2504919118; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE; tRNA modification GTPase mnmE 287675 10578730 Trebr_0253 Treponema brennaborense DSM 12168 tRNA modification GTPase mnmE YP_004438833.1 286146 R 906968 CDS YP_004438834.1 332296912 10578731 complement(287692..288771) 1 NC_015500.1 InterPro IPR000326; KEGG: tde:TDE2181 PAP2 family protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: PAP2 family protein; IMG reference gene:2504919119; PFAM: PAP2 superfamily; phosphoesterase PA-phosphatase-like protein 288771 10578731 Trebr_0254 Treponema brennaborense DSM 12168 phosphoesterase PA-phosphatase-like protein YP_004438834.1 287692 R 906968 CDS YP_004438835.1 332296913 10578732 complement(288761..291094) 1 NC_015500.1 COGs: COG1306 conserved hypothetical protein; KEGG: tde:TDE2182 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504919120; hypothetical protein 291094 10578732 Trebr_0255 Treponema brennaborense DSM 12168 hypothetical protein YP_004438835.1 288761 R 906968 CDS YP_004438836.1 332296914 10578733 complement(291118..292671) 1 NC_015500.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524; KEGG: elm:ELI_4583 transcriptional regulator; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: uncharacterized protein; IMG reference gene:2504919121; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator 292671 10578733 Trebr_0256 Treponema brennaborense DSM 12168 GntR family transcriptional regulator YP_004438836.1 291118 R 906968 CDS YP_004438837.1 332296915 10578734 complement(292801..293823) 1 NC_015500.1 COGs: COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: toc:Toce_0687 ApbE family lipoprotein; PFAM: ApbE-like lipoprotein; SPTR: Thiamin biosynthesis lipoprotein; IMG reference gene:2504919122; PFAM: ApbE family; ApbE family lipoprotein 293823 10578734 Trebr_0257 Treponema brennaborense DSM 12168 ApbE family lipoprotein YP_004438837.1 292801 R 906968 CDS YP_004438838.1 332296916 10578735 293971..296043 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR001450:IPR007202; KEGG: ssm:Spirs_3433 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504919123; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 296043 10578735 Trebr_0258 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004438838.1 293971 D 906968 CDS YP_004438839.1 332296917 10578736 complement(296130..297947) 1 NC_015500.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterPro IPR004365:IPR004364:IPR004115:IPR004524; KEGG: tde:TDE1587 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; GAD domain; PRIAM: Aspartate--tRNA ligase; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type; IMG reference gene:2504919124; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type; aspartyl-tRNA synthetase 297947 10578736 Trebr_0259 Treponema brennaborense DSM 12168 aspartyl-tRNA synthetase YP_004438839.1 296130 R 906968 CDS YP_004438840.1 332296918 10578737 complement(297994..298371) 1 NC_015500.1 COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: eel:EUBELI_20470 peptidylprolyl isomerase; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis; IMG reference gene:2504919125; PFAM: Dinitrogenase iron-molybdenum cofactor; dinitrogenase iron-molybdenum cofactor biosynthesis protein 298371 10578737 Trebr_0260 Treponema brennaborense DSM 12168 dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_004438840.1 297994 R 906968 CDS YP_004438841.1 332296919 10578738 complement(298459..299037) 1 NC_015500.1 COGs: COG1971 membrane protein; HAMAP: UPF0059 membrane protein yebN; InterPro IPR003810; KEGG: ele:Elen_1273 protein of unknown function DUF204; PFAM: Protein of unknown function DUF204; SPTR: UPF0059 membrane protein CLOSTMETH_02454; IMG reference gene:2504919126; PFAM: Domain of unknown function DUF; hypothetical protein 299037 10578738 Trebr_0261 Treponema brennaborense DSM 12168 hypothetical protein YP_004438841.1 298459 R 906968 CDS YP_004438842.1 332296920 10578739 299180..300196 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ttr:Tter_0828 transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504919127; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 300196 10578739 Trebr_0262 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004438842.1 299180 D 906968 CDS YP_004438843.1 332296921 10578740 300278..300673 1 NC_015500.1 COGs: COG1869 ABC-type ribose transport system auxiliary component; HAMAP: D-ribose pyranase; InterPro IPR007721; KEGG: lps:LPST_C2989 D-ribose pyranase; PFAM: RbsD/FucU transport; SPTR: D-ribose pyranase; IMG reference gene:2504919128; PFAM: RbsD / FucU transport protein family; D-ribose pyranase 300673 10578740 Trebr_0263 Treponema brennaborense DSM 12168 D-ribose pyranase YP_004438843.1 300278 D 906968 CDS YP_004438844.1 332296922 10578741 300687..302180 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: bld:BLi03843 RbsA; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; IMG reference gene:2504919129; PFAM: ABC transporter; monosaccharide-transporting ATPase 302180 10578741 Trebr_0264 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004438844.1 300687 D 906968 CDS YP_004438845.1 332296923 10578742 302177..303115 1 NC_015500.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sha:SH0178 ribose ABC transporter permease; PFAM: Bacterial inner-membrane translocator; SPTR: uncharacterized protein; IMG reference gene:2504919130; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 303115 10578742 Trebr_0265 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438845.1 302177 D 906968 CDS YP_004438846.1 332296924 10578743 303125..304009 1 NC_015500.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: esi:Exig_2383 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: uncharacterized protein; IMG reference gene:2504919131; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 304009 10578743 Trebr_0266 Treponema brennaborense DSM 12168 periplasmic binding protein/LacI transcriptional regulator YP_004438846.1 303125 D 906968 CDS YP_004438847.1 332296925 10578744 304079..305005 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: csh:Closa_3271 ribokinase; PFAM: Carbohydrate/purine kinase; PRIAM: Ribokinase; SPTR: uncharacterized protein; IMG reference gene:2504919132; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase; Ribokinase 305005 10578744 Trebr_0267 Treponema brennaborense DSM 12168 Ribokinase YP_004438847.1 304079 D 906968 CDS YP_004438848.1 332296926 10578745 305109..306932 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE2549 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919133; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 306932 10578745 Trebr_0268 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004438848.1 305109 D 906968 CDS YP_004438849.1 332296927 10578746 307092..307703 1 NC_015500.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tde:TDE0955 LemA family protein; PFAM: LemA; SPTR: LemA family protein; IMG reference gene:2504919134; PFAM: LemA family; LemA family protein 307703 10578746 Trebr_0269 Treponema brennaborense DSM 12168 LemA family protein YP_004438849.1 307092 D 906968 CDS YP_004438850.1 332296928 10578747 307729..308463 1 NC_015500.1 COGs: COG3762 membrane protein; InterPro IPR007621; KEGG: tde:TDE2528 hypothetical protein; PFAM: Protein of unknown function DUF477; SPTR: uncharacterized protein; IMG reference gene:2504919135; PFAM: Domain of unknown function (DUF477); hypothetical protein 308463 10578747 Trebr_0270 Treponema brennaborense DSM 12168 hypothetical protein YP_004438850.1 307729 D 906968 CDS YP_004438851.1 332296929 10578748 308453..309253 1 NC_015500.1 COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: tde:TDE0956 hypothetical protein; PFAM: Protein of unknown function DUF477; SPTR: Beta-propeller domain of methanol dehydrogenase type protein; IMG reference gene:2504919136; PFAM: Domain of unknown function (DUF477); hypothetical protein 309253 10578748 Trebr_0271 Treponema brennaborense DSM 12168 hypothetical protein YP_004438851.1 308453 D 906968 CDS YP_004438852.1 332296930 10578749 complement(309525..310055) 1 NC_015500.1 InterPro IPR000182; KEGG: gbm:Gbem_1244 GNAT family acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504919137; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 310055 10578749 Trebr_0272 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004438852.1 309525 R 906968 CDS YP_004438853.1 332296931 10578750 complement(310062..311363) 1 NC_015500.1 KEGG: tmz:Tmz1t_0258 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919138; hypothetical protein 311363 10578750 Trebr_0273 Treponema brennaborense DSM 12168 hypothetical protein YP_004438853.1 310062 R 906968 CDS YP_004438854.1 332296932 10578751 311845..313692 1 NC_015500.1 COGs: COG0442 Prolyl-tRNA synthetase; HAMAP: Prolyl-tRNA synthetase; InterPro IPR002314:IPR007214:IPR004154:IPR004500; KEGG: tde:TDE2220 prolyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; YbaK/aminoacyl-tRNA synthetase associated region; Anticodon-binding; SPTR: Prolyl-tRNA synthetase; TIGRFAM: Prolyl-tRNA synthetase, class IIa, bacterial; IMG reference gene:2504919139; PFAM: Anticodon binding domain; YbaK / prolyl-tRNA synthetases associated domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II; prolyl-tRNA synthetase 313692 10578751 Trebr_0274 Treponema brennaborense DSM 12168 prolyl-tRNA synthetase YP_004438854.1 311845 D 906968 CDS YP_004438855.1 332296933 10578752 313706..314872 1 NC_015500.1 KEGG: tde:TDE2221 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919140; hypothetical protein 314872 10578752 Trebr_0275 Treponema brennaborense DSM 12168 hypothetical protein YP_004438855.1 313706 D 906968 CDS YP_004438856.1 332296934 10578753 complement(315122..315976) 1 NC_015500.1 COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: tde:TDE2081 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: uncharacterized protein; IMG reference gene:2504919141; PFAM: Sporulation and spore germination; Lipoprotein LpqB, GerMN domain-containing protein 315976 10578753 Trebr_0276 Treponema brennaborense DSM 12168 Lipoprotein LpqB, GerMN domain-containing protein YP_004438856.1 315122 R 906968 CDS YP_004438857.1 332296935 10578754 complement(316149..317993) 1 NC_015500.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR017688; KEGG: tde:TDE1415 nucleotidyl transferase/aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: 2-aminoethylphosphonate--pyruvate transaminase; SPTR: Nucleotidyl transferase/aminotransferase, class V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; IMG reference gene:2504919142; PFAM: Nucleotidyl transferase; Aminotransferase class-V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate aminotransferase 317993 10578754 Trebr_0277 Treponema brennaborense DSM 12168 2-aminoethylphosphonate aminotransferase YP_004438857.1 316149 R 906968 CDS YP_004438858.1 332296936 10578755 complement(318011..319162) 1 NC_015500.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR011766:IPR017684; KEGG: tde:TDE1414 phosphonopyruvate decarboxylase, PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Phosphonopyruvate decarboxylase; SPTR: Phosphonopyruvate decarboxylase, ; TIGRFAM: Phosphonopyruvate decarboxylase; IMG reference gene:2504919143; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase; phosphonopyruvate decarboxylase 319162 10578755 Trebr_0278 Treponema brennaborense DSM 12168 phosphonopyruvate decarboxylase YP_004438858.1 318011 R 906968 CDS YP_004438859.1 332296937 10578756 complement(319193..320539) 1 NC_015500.1 COGs: COG2513 PEP phosphonomutase; InterPro IPR004820:IPR004821:IPR012698; KEGG: tde:TDE1413 cytidylyltransferase/phosphoenolpyruvate phosphomutase, PFAM: Cytidylyltransferase; PRIAM: Phosphoenolpyruvate mutase; SPTR: Cytidylyltransferase/phosphoenolpyruvate phosphomutase, ; TIGRFAM: Phosphoenolpyruvate phosphomutase, core; Cytidyltransferase-related; IMG reference gene:2504919144; PFAM: Cytidylyltransferase; TIGRFAM: phosphoenolpyruvate phosphomutase; phosphoenolpyruvate phosphomutase 320539 10578756 Trebr_0279 Treponema brennaborense DSM 12168 phosphoenolpyruvate phosphomutase YP_004438859.1 319193 R 906968 CDS YP_004438860.1 332296938 10578757 320675..322393 1 NC_015500.1 KEGG: ank:AnaeK_4433 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919145; hypothetical protein 322393 10578757 Trebr_0280 Treponema brennaborense DSM 12168 hypothetical protein YP_004438860.1 320675 D 906968 CDS YP_004438861.1 332296939 10578758 322459..324492 1 NC_015500.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184:IPR001150; KEGG: dsy:DSY3016 pyruvate-formate lyase; PFAM: Formate C-acetyltransferase glycine radical; Pyruvate formate-lyase, PFL; PRIAM: Formate C-acetyltransferase; SPTR: pyruvate-formate lyase; IMG reference gene:2504919146; PFAM: Glycine radical; Pyruvate formate lyase; Formate C-acetyltransferase 324492 10578758 Trebr_0281 Treponema brennaborense DSM 12168 Formate C-acetyltransferase YP_004438861.1 322459 D 906968 CDS YP_004438862.1 332296940 10578759 324489..325265 1 NC_015500.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197; KEGG: mth:MTH345 pyruvate formate-lyase 2 activating enzyme; PFAM: Radical SAM; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: Pyruvate-formate lyase-activating enzyme; IMG reference gene:2504919147; PFAM: Radical SAM superfamily; (formate-C-acetyltransferase)-activating protein 325265 10578759 Trebr_0282 Treponema brennaborense DSM 12168 (formate-C-acetyltransferase)-activating protein YP_004438862.1 324489 D 906968 CDS YP_004438863.1 332296941 10578760 325276..326739 1 NC_015500.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ere:EUBREC_2621 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2504919148; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 326739 10578760 Trebr_0283 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004438863.1 325276 D 906968 CDS YP_004438864.1 332296942 10578761 326821..327027 1 NC_015500.1 IMG reference gene:2504919149; hypothetical protein 327027 10578761 Trebr_0284 Treponema brennaborense DSM 12168 hypothetical protein YP_004438864.1 326821 D 906968 CDS YP_004438865.1 332296943 10578763 327314..328426 1 NC_015500.1 COGs: COG0562 UDP-galactopyranose mutase; InterPro IPR015899:IPR004379; KEGG: bfs:BF1370 LPS biosynthesis related UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase, C-terminal; PRIAM: UDP-galactopyranose mutase; SPTR: LPS biosynthesis related UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; IMG reference gene:2504919151; PFAM: UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; UDP-galactopyranose mutase 328426 10578763 Trebr_0286 Treponema brennaborense DSM 12168 UDP-galactopyranose mutase YP_004438865.1 327314 D 906968 CDS YP_004438866.1 332296944 10578764 328404..329315 1 NC_015500.1 KEGG: cbi:CLJ_B2914 exopolysaccharide biosynthesis protein; SPTR: Exopolysaccharide biosynthesis protein; IMG reference gene:2504919152; exopolysaccharide biosynthesis protein 329315 10578764 Trebr_0287 Treponema brennaborense DSM 12168 exopolysaccharide biosynthesis protein YP_004438866.1 328404 D 906968 CDS YP_004438867.1 332296945 10578765 329321..330235 1 NC_015500.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: fsu:Fisuc_0984 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504919153; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 330235 10578765 Trebr_0288 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004438867.1 329321 D 906968 CDS YP_004438868.1 332296946 10578766 330240..331400 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: nhl:Nhal_3660 glycosyl transferase family 2; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyltransferase, group 1 family protein; IMG reference gene:2504919154; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 331400 10578766 Trebr_0289 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004438868.1 330240 D 906968 CDS YP_004438869.1 332296947 10578767 331391..332227 1 NC_015500.1 KEGG: ljf:FI9785_687 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919155; PFAM: Glycosyl transferase family 2; hypothetical protein 332227 10578767 Trebr_0290 Treponema brennaborense DSM 12168 hypothetical protein YP_004438869.1 331391 D 906968 CDS YP_004438870.1 332296948 10578768 332322..333488 1 NC_015500.1 COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: efe:EFER_2111 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose dehydrogenase; TIGRFAM: Nucleotide sugar dehydrogenase; IMG reference gene:2504919156; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; nucleotide sugar dehydrogenase 333488 10578768 Trebr_0291 Treponema brennaborense DSM 12168 nucleotide sugar dehydrogenase YP_004438870.1 332322 D 906968 CDS YP_004438871.1 332296949 10578769 333495..334661 1 NC_015500.1 KEGG: cch:Cag_1863 glycosyl transferase, group 1 family protein; SPTR: Glycosyl transferase, group 1 family protein; IMG reference gene:2504919157; hypothetical protein 334661 10578769 Trebr_0292 Treponema brennaborense DSM 12168 hypothetical protein YP_004438871.1 333495 D 906968 CDS YP_004438872.1 332296950 10578770 334689..335816 1 NC_015500.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653:IPR012749; KEGG: cbk:CLL_A3243 TDP-4-oxo-6-deoxy-D-glucose transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; TIGRFAM: TDP-4-keto-6-deoxy-D-glucose transaminase; IMG reference gene:2504919158; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: TDP-4-keto-6-deoxy-D-glucose transaminase; TDP-4-keto-6-deoxy-D-glucose transaminase 335816 10578770 Trebr_0293 Treponema brennaborense DSM 12168 TDP-4-keto-6-deoxy-D-glucose transaminase YP_004438872.1 334689 D 906968 CDS YP_004438873.1 332296951 10578771 335813..336736 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dol:Dole_1293 ribonuclease III; PFAM: Glycosyl transferase, family 2; SPTR: Bactoprenol glucosyl transferase; IMG reference gene:2504919159; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 336736 10578771 Trebr_0294 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004438873.1 335813 D 906968 CDS YP_004438874.1 332296952 10578772 336726..337082 1 NC_015500.1 InterPro IPR000620; KEGG: shi:Shel_14330 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: EamA-like transporter family; IMG reference gene:2504919160; PFAM: EamA-like transporter family; hypothetical protein 337082 10578772 Trebr_0295 Treponema brennaborense DSM 12168 hypothetical protein YP_004438874.1 336726 D 906968 CDS YP_004438875.1 332296953 10578773 337075..337416 1 NC_015500.1 InterPro IPR000620; KEGG: elm:ELI_1406 EamA-like transporter family; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: EamA-like transporter family; IMG reference gene:2504919161; PFAM: EamA-like transporter family; hypothetical protein 337416 10578773 Trebr_0296 Treponema brennaborense DSM 12168 hypothetical protein YP_004438875.1 337075 D 906968 CDS YP_004438876.1 332296954 10578774 337453..339282 1 NC_015500.1 KEGG: bpb:bpr_I0355 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919162; hypothetical protein 339282 10578774 Trebr_0297 Treponema brennaborense DSM 12168 hypothetical protein YP_004438876.1 337453 D 906968 CDS YP_004438877.1 332296955 10578775 339369..340421 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bxe:Bxe_A3712 glycosyl transferases group 1 protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1 family; IMG reference gene:2504919163; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 340421 10578775 Trebr_0298 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004438877.1 339369 D 906968 CDS YP_004438878.1 332296956 10578776 complement(340513..342429) 1 NC_015500.1 KEGG: tde:TDE1231 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919164; hypothetical protein 342429 10578776 Trebr_0299 Treponema brennaborense DSM 12168 hypothetical protein YP_004438878.1 340513 R 906968 CDS YP_004438879.1 332296957 10578777 complement(342456..344297) 1 NC_015500.1 KEGG: tde:TDE1234 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919165; hypothetical protein 344297 10578777 Trebr_0300 Treponema brennaborense DSM 12168 hypothetical protein YP_004438879.1 342456 R 906968 CDS YP_004438880.1 332296958 10578778 344438..347143 1 NC_015500.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708; KEGG: tde:TDE1436 inner membrane protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Inner membrane protein; IMG reference gene:2504919166; PFAM: 60Kd inner membrane protein; Type I phosphodiesterase / nucleotide pyrophosphatase; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; 60 kDa inner membrane insertion protein 347143 10578778 Trebr_0301 Treponema brennaborense DSM 12168 60 kDa inner membrane insertion protein YP_004438880.1 344438 D 906968 CDS YP_004438881.1 332296959 10578779 347143..348387 1 NC_015500.1 InterPro IPR007554; KEGG: tde:TDE1435 hypothetical protein; PFAM: CDP-glycerol glycerophosphotransferase; SPTR: uncharacterized protein; IMG reference gene:2504919167; PFAM: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; CDP- glycerol:poly(glycerophosphate)glycerophosphotransferase 348387 10578779 Trebr_0302 Treponema brennaborense DSM 12168 CDP- glycerol:poly(glycerophosphate)glycerophosphotransferase YP_004438881.1 347143 D 906968 CDS YP_004438882.1 332296960 10578780 348384..349460 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ipo:Ilyop_2681 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504919168; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 349460 10578780 Trebr_0303 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004438882.1 348384 D 906968 CDS YP_004438883.1 332296961 10578781 349438..350556 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cow:Calow_0028 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase; IMG reference gene:2504919169; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 350556 10578781 Trebr_0304 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004438883.1 349438 D 906968 CDS YP_004438884.1 332296962 10578783 complement(352101..354230) 1 NC_015500.1 COGs: COG0855 Polyphosphate kinase; HAMAP: Polyphosphate kinase; InterPro IPR003414; KEGG: hmo:HM1_0232 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1; IMG reference gene:2504919171; PFAM: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1; polyphosphate kinase 354230 10578783 Trebr_0306 Treponema brennaborense DSM 12168 polyphosphate kinase YP_004438884.1 352101 R 906968 CDS YP_004438885.1 332296963 10578784 complement(354269..355828) 1 NC_015500.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: sta:STHERM_c22140 hypothetical protein; PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Ppx/GppA phosphatase; IMG reference gene:2504919172; PFAM: HD domain; Ppx/GppA phosphatase family; Ppx/GppA phosphatase 355828 10578784 Trebr_0307 Treponema brennaborense DSM 12168 Ppx/GppA phosphatase YP_004438885.1 354269 R 906968 CDS YP_004438886.1 332296964 10578785 complement(355866..357296) 1 NC_015500.1 COGs: COG1626 Neutral trehalase; KEGG: tpp:TPASS_0931 hypothetical protein; SPTR: Trehalase; IMG reference gene:2504919173; PFAM: Trehalase; hypothetical protein 357296 10578785 Trebr_0308 Treponema brennaborense DSM 12168 hypothetical protein YP_004438886.1 355866 R 906968 CDS YP_004438887.1 332296965 10578786 357394..359727 1 NC_015500.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterPro IPR006075:IPR018027:IPR006034; KEGG: sta:STHERM_c22190 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; PFAM: Asn/Gln amidotransferase; Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Asparaginase/glutaminase; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; IMG reference gene:2504919174; PFAM: GatB/GatE catalytic domain; Asparaginase; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Asn/Gln amidotransferase 359727 10578786 Trebr_0309 Treponema brennaborense DSM 12168 Asn/Gln amidotransferase YP_004438887.1 357394 D 906968 CDS YP_004438888.1 332296966 10578787 complement(359768..361561) 1 NC_015500.1 KEGG: tde:TDE0994 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919175; hypothetical protein 361561 10578787 Trebr_0310 Treponema brennaborense DSM 12168 hypothetical protein YP_004438888.1 359768 R 906968 CDS YP_004438889.1 332296967 10578788 361625..363133 1 NC_015500.1 InterPro IPR019734:IPR001440; KEGG: tpp:TPASS_0954 hypothetical protein; PFAM: Tetratricopeptide TPR-1; SPTR: uncharacterized protein; IMG reference gene:2504919176; PFAM: Tetratricopeptide repeat; hypothetical protein 363133 10578788 Trebr_0311 Treponema brennaborense DSM 12168 hypothetical protein YP_004438889.1 361625 D 906968 CDS YP_004438890.1 332296968 10578789 363166..364359 1 NC_015500.1 COGs: COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein); InterPro IPR002816:IPR005230; KEGG: tde:TDE0026 TraB family protein; PFAM: Pheromone shutdown-related, TraB; SPTR: TraB family protein; TIGRFAM: Pheromone shutdown, TraB; IMG reference gene:2504919177; PFAM: TraB family; TIGRFAM: pheromone shutdown-related protein TraB; TraB family protein 364359 10578789 Trebr_0312 Treponema brennaborense DSM 12168 TraB family protein YP_004438890.1 363166 D 906968 CDS YP_004438891.1 332296969 10578790 364385..365125 1 NC_015500.1 KEGG: tde:TDE2545 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919178; hypothetical protein 365125 10578790 Trebr_0313 Treponema brennaborense DSM 12168 hypothetical protein YP_004438891.1 364385 D 906968 CDS YP_004438892.1 332296970 10578791 365149..365847 1 NC_015500.1 COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: tde:TDE0863 MgtC family protein; PFAM: MgtC/SapB transporter; SPTR: MgtC family protein; IMG reference gene:2504919179; PFAM: MgtC family; MgtC/SapB transporter 365847 10578791 Trebr_0314 Treponema brennaborense DSM 12168 MgtC/SapB transporter YP_004438892.1 365149 D 906968 CDS YP_004438893.1 332296971 10578792 complement(365902..366321) 1 NC_015500.1 KEGG: chy:CHY_1722 PilT domain-containing protein; SPTR: PIN domain protein; IMG reference gene:2504919180; PilT domain-containing protein 366321 10578792 Trebr_0315 Treponema brennaborense DSM 12168 PilT domain-containing protein YP_004438893.1 365902 R 906968 CDS YP_004438894.1 332296972 10578793 complement(366318..366542) 1 NC_015500.1 IMG reference gene:2504919181; hypothetical protein 366542 10578793 Trebr_0316 Treponema brennaborense DSM 12168 hypothetical protein YP_004438894.1 366318 R 906968 CDS YP_004438895.1 332296973 10578794 366717..367559 1 NC_015500.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: ssm:Spirs_0338 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Hydrolase; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504919182; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; cof family hydrolase 367559 10578794 Trebr_0317 Treponema brennaborense DSM 12168 cof family hydrolase YP_004438895.1 366717 D 906968 CDS YP_004438896.1 332296974 10578795 367568..368536 1 NC_015500.1 COGs: COG2524 transcriptional regulator protein; InterPro IPR000644:IPR003594; KEGG: ssm:Spirs_1313 signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; ATP-binding region, ATPase-like; SMART: Cystathionine beta-synthase, core; SPTR: signal transduction protein with CBS domains; IMG reference gene:2504919183; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction protein with CBS domains 368536 10578795 Trebr_0318 Treponema brennaborense DSM 12168 signal transduction protein with CBS domains YP_004438896.1 367568 D 906968 CDS YP_004438897.1 332296975 10578796 368655..369029 1 NC_015500.1 KEGG: sta:STHERM_c13820 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919184; PFAM: DRTGG domain; hypothetical protein 369029 10578796 Trebr_0319 Treponema brennaborense DSM 12168 hypothetical protein YP_004438897.1 368655 D 906968 CDS YP_004438898.1 332296976 10578797 369145..369894 1 NC_015500.1 InterPro IPR003141:IPR004013; KEGG: ssm:Spirs_1311 PHP domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; IMG reference gene:2504919185; PFAM: PHP domain; PHP domain-containing protein 369894 10578797 Trebr_0320 Treponema brennaborense DSM 12168 PHP domain-containing protein YP_004438898.1 369145 D 906968 CDS YP_004438899.1 332296977 10578798 complement(369910..370743) 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: gym:GYMC10_1096 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region; SPTR: uncharacterized protein; IMG reference gene:2504919186; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 370743 10578798 Trebr_0321 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004438899.1 369910 R 906968 CDS YP_004438900.1 332296978 10578799 complement(370718..372562) 1 NC_015500.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: ckn:Calkro_0107 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504919187; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 372562 10578799 Trebr_0322 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004438900.1 370718 R 906968 CDS YP_004438901.1 332296979 10578800 372750..374051 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csc:Csac_2516 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family; IMG reference gene:2504919188; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 374051 10578800 Trebr_0323 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438901.1 372750 D 906968 CDS YP_004438902.1 332296980 10578801 374144..375025 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ckn:Calkro_0109 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504919189; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 375025 10578801 Trebr_0324 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438902.1 374144 D 906968 CDS YP_004438903.1 332296981 10578802 375048..375878 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: tte:TTE2347 sugar permeases; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Sugar permeases; IMG reference gene:2504919190; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 375878 10578802 Trebr_0325 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438903.1 375048 D 906968 CDS YP_004438904.1 332296982 10578803 375883..377244 1 NC_015500.1 COGs: COG5520 O-Glycosyl hydrolase; InterPro IPR001139; KEGG: cpy:Cphy_0858 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 30; PRIAM: Glucosylceramidase; SPTR: Glucosylceramidase; IMG reference gene:2504919191; PFAM: O-Glycosyl hydrolase family 30; Glucosylceramidase 377244 10578803 Trebr_0326 Treponema brennaborense DSM 12168 Glucosylceramidase YP_004438904.1 375883 D 906968 CDS YP_004438905.1 332296983 10578804 complement(377663..379390) 1 NC_015500.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tde:TDE0942 long-chain-fatty-acid--CoA ligase, PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: long-chain-fatty-acid--CoA ligase; IMG reference gene:2504919192; PFAM: AMP-binding enzyme; long-chain-fatty-acid--CoA ligase 379390 10578804 Trebr_0327 Treponema brennaborense DSM 12168 long-chain-fatty-acid--CoA ligase YP_004438905.1 377663 R 906968 CDS YP_004438906.1 332296984 10578805 379547..380653 1 NC_015500.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: tde:TDE0941 NLP/P60 family protein; PFAM: NLP/P60; SPTR: NLP/P60 family protein; IMG reference gene:2504919193; PFAM: NlpC/P60 family; NLP/P60 protein 380653 10578805 Trebr_0328 Treponema brennaborense DSM 12168 NLP/P60 protein YP_004438906.1 379547 D 906968 CDS YP_004438907.1 332296985 10578806 380820..381623 1 NC_015500.1 KEGG: tde:TDE2164 hypothetical protein; SPTR: lipoprotein; IMG reference gene:2504919194; hypothetical protein 381623 10578806 Trebr_0329 Treponema brennaborense DSM 12168 hypothetical protein YP_004438907.1 380820 D 906968 CDS YP_004438908.1 332296986 10578807 381760..382242 1 NC_015500.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c13780 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein; IMG reference gene:2504919195; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit 382242 10578807 Trebr_0330 Treponema brennaborense DSM 12168 NADH dehydrogenase (ubiquinone) 24 kDa subunit YP_004438908.1 381760 D 906968 CDS YP_004438909.1 332296987 10578808 382246..382845 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594; KEGG: ssm:Spirs_3690 histidine kinase; PFAM: ATP-binding region, ATPase-like; SPTR: Histidine kinase; IMG reference gene:2504919196; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; histidine kinase 382845 10578808 Trebr_0331 Treponema brennaborense DSM 12168 histidine kinase YP_004438909.1 382246 D 906968 CDS YP_004438910.1 332296988 10578809 382846..383241 1 NC_015500.1 KEGG: ssm:Spirs_3689 NAD(P)-dependent iron-only hydrogenase iron-sulfur protein; SPTR: NAD(P)-dependent iron-only hydrogenase iron-sulfur protein; IMG reference gene:2504919197; NAD(P)-dependent iron-only hydrogenase iron-sulfur protein 383241 10578809 Trebr_0332 Treponema brennaborense DSM 12168 NAD(P)-dependent iron-only hydrogenase iron-sulfur protein YP_004438910.1 382846 D 906968 CDS YP_004438911.1 332296989 10578810 383261..385042 1 NC_015500.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575:IPR001450; KEGG: ssm:Spirs_3688 NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; IMG reference gene:2504919198; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; NADH dehydrogenase (quinone) 385042 10578810 Trebr_0333 Treponema brennaborense DSM 12168 NADH dehydrogenase (quinone) YP_004438911.1 383261 D 906968 CDS YP_004438912.1 332296990 10578811 385052..386794 1 NC_015500.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: ssm:Spirs_3687 NAD(P)-dependent iron-only hydrogenase catalytic subunit; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Iron hydrogenase, small subunit-like; PRIAM: Ferredoxin hydrogenase; SPTR: NAD(P)-dependent iron-only hydrogenase catalytic subunit; TIGRFAM: Iron hydrogenase, subset; IMG reference gene:2504919199; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; hydrogenase, Fe-only 386794 10578811 Trebr_0334 Treponema brennaborense DSM 12168 hydrogenase, Fe-only YP_004438912.1 385052 D 906968 CDS YP_004438913.1 332296991 10578812 complement(386913..388844) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR013163; KEGG: tde:TDE0178 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919200; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 388844 10578812 Trebr_0335 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer with Cache sensor YP_004438913.1 386913 R 906968 CDS YP_004438914.1 332296992 10578813 389036..389275 1 NC_015500.1 InterPro IPR007236; PFAM: SlyX; IMG reference gene:2504919201; PFAM: SlyX; SlyX family protein 389275 10578813 Trebr_0336 Treponema brennaborense DSM 12168 SlyX family protein YP_004438914.1 389036 D 906968 CDS YP_004438915.1 332296993 10578814 389403..390635 1 NC_015500.1 KEGG: ssm:Spirs_0506 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919202; hypothetical protein 390635 10578814 Trebr_0337 Treponema brennaborense DSM 12168 hypothetical protein YP_004438915.1 389403 D 906968 CDS YP_004438916.1 332296994 10578815 390784..392382 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ssm:Spirs_0505 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ribose import ATP-binding protein RbsA; IMG reference gene:2504919203; PFAM: ABC transporter; monosaccharide-transporting ATPase 392382 10578815 Trebr_0338 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004438916.1 390784 D 906968 CDS YP_004438917.1 332296995 10578816 392379..393443 1 NC_015500.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: aco:Amico_0359 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: ABC transporter integral membrane protein; IMG reference gene:2504919204; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 393443 10578816 Trebr_0339 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438917.1 392379 D 906968 CDS YP_004438918.1 332296996 10578817 393440..394588 1 NC_015500.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: aco:Amico_0360 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: ABC transporter integral membrane protein; IMG reference gene:2504919205; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 394588 10578817 Trebr_0340 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438918.1 393440 D 906968 CDS YP_004438919.1 332296997 10578818 394588..394968 1 NC_015500.1 KEGG: tai:Taci_0124 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919206; hypothetical protein 394968 10578818 Trebr_0341 Treponema brennaborense DSM 12168 hypothetical protein YP_004438919.1 394588 D 906968 CDS YP_004438920.1 332296998 10578819 394995..395612 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: cdf:CD3376 transcriptional regulator; PFAM: Signal transduction response regulator, C-terminal; SPTR: Transcriptional regulatory protein; IMG reference gene:2504919207; PFAM: Transcriptional regulatory protein, C terminal; winged helix family transcriptional regulator 395612 10578819 Trebr_0342 Treponema brennaborense DSM 12168 winged helix family transcriptional regulator YP_004438920.1 394995 D 906968 CDS YP_004438921.1 332296999 10578820 395743..397062 1 NC_015500.1 COGs: COG3969 phosphoadenosine phosphosulfate sulfotransferase; InterPro IPR011063; KEGG: elm:ELI_1852 Co-activator of prophage gene expression IbrA; PFAM: PP-loop; SPTR: Co-activator of prophage gene expression IbrA; IMG reference gene:2504919208; PFAM: Domain of unknown function (DUF3440); Phosphoadenosine phosphosulfate reductase family; PP-loop domain-containing protein 397062 10578820 Trebr_0343 Treponema brennaborense DSM 12168 PP-loop domain-containing protein YP_004438921.1 395743 D 906968 CDS YP_004438922.1 332297000 10578821 397062..397598 1 NC_015500.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115; KEGG: cdl:CDR20291_0520 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: uncharacterized protein; IMG reference gene:2504919209; PFAM: ParB-like nuclease domain; ParB domain-containing protein nuclease 397598 10578821 Trebr_0344 Treponema brennaborense DSM 12168 ParB domain-containing protein nuclease YP_004438922.1 397062 D 906968 CDS YP_004438923.1 332297001 10578822 complement(397616..399226) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: bgf:BC1003_2114 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504919210; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 399226 10578822 Trebr_0345 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004438923.1 397616 R 906968 CDS YP_004438924.1 332297002 10578823 complement(399563..400357) 1 NC_015500.1 COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: tde:TDE2295 mechanosensitive ion channel family protein; PFAM: Mechanosensitive ion channel MscS; SPTR: Mechanosensitive ion channel family protein; IMG reference gene:2504919211; PFAM: Mechanosensitive ion channel; mechanosensitive ion channel MscS 400357 10578823 Trebr_0346 Treponema brennaborense DSM 12168 mechanosensitive ion channel MscS YP_004438924.1 399563 R 906968 CDS YP_004438925.1 332297003 10578824 complement(400359..401066) 1 NC_015500.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003583:IPR003651:IPR005759; KEGG: rpd:RPD_0381 endonuclease III; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD domain; Helix-hairpin-helix DNA-binding motif, class 1; Endonuclease III-like, iron-sulphur cluster loop motif; SPTR: Endonuclease III / DNA-(Apurinic or apyrimidinic site) lyase; TIGRFAM: Endonuclease III/Nth; IMG reference gene:2504919212; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III; endonuclease III 401066 10578824 Trebr_0347 Treponema brennaborense DSM 12168 endonuclease III YP_004438925.1 400359 R 906968 CDS YP_004438926.1 332297004 10578825 complement(401081..402253) 1 NC_015500.1 COGs: COG0192 S-adenosylmethionine synthetase; HAMAP: S-adenosylmethionine synthase; InterPro IPR002133; KEGG: tde:TDE2470 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; IMG reference gene:2504919213; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, N-terminal domain; S-adenosylmethionine synthetase, central domain; TIGRFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthase 402253 10578825 Trebr_0348 Treponema brennaborense DSM 12168 S-adenosylmethionine synthase YP_004438926.1 401081 R 906968 CDS YP_004438927.1 332297005 10578826 402466..402774 1 NC_015500.1 InterPro IPR004193; KEGG: dol:Dole_0850 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Glycoside hydrolase, family 13-like protein; IMG reference gene:2504919214; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); glycoside hydrolase family protein 402774 10578826 Trebr_0349 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004438927.1 402466 D 906968 CDS YP_004438928.1 332297006 10578827 complement(402851..404617) 1 NC_015500.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterProIPR008333:IPR001433:IPR019480:IPR012135:IPR 005720; KEGG: apr:Apre_0785 dihydroorotate dehydrogenase family protein; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region; PRIAM: Dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase; TIGRFAM: Dihydroorotate dehydrogenase, class 1, core; IMG reference gene:2504919215; PFAM: Dihydroorotate dehydrogenase; Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein; dihydroorotate dehydrogenase family protein 404617 10578827 Trebr_0350 Treponema brennaborense DSM 12168 dihydroorotate dehydrogenase family protein YP_004438928.1 402851 R 906968 CDS YP_004438929.1 332297007 10578828 complement(404628..405590) 1 NC_015500.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; HAMAP: Orotidine 5'-phosphate decarboxylase; InterPro IPR001754:IPR011995; KEGG: cbl:CLK_2636 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504919216; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Orotidine 5'-phosphate decarboxylase 405590 10578828 Trebr_0351 Treponema brennaborense DSM 12168 Orotidine 5'-phosphate decarboxylase YP_004438929.1 404628 R 906968 CDS YP_004438930.1 332297008 10578829 405835..407091 1 NC_015500.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: dal:Dalk_4338 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504919217; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain; Radical SAM domain protein 407091 10578829 Trebr_0352 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004438930.1 405835 D 906968 CDS YP_004438931.1 332297009 10578830 407093..408373 1 NC_015500.1 KEGG: ath:AT1G10740 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919218; hypothetical protein 408373 10578830 Trebr_0353 Treponema brennaborense DSM 12168 hypothetical protein YP_004438931.1 407093 D 906968 CDS YP_004438932.1 332297010 10578831 408393..412814 1 NC_015500.1 COGs: COG3899 ATPase; InterPro IPR019734:IPR001440; KEGG: lic:LIC13201 adenylate/guanylate cyclase; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase; IMG reference gene:2504919219; PFAM: Adenylate and Guanylate cyclase catalytic domain; hypothetical protein 412814 10578831 Trebr_0354 Treponema brennaborense DSM 12168 hypothetical protein YP_004438932.1 408393 D 906968 CDS YP_004438933.1 332297011 10578832 412827..414590 1 NC_015500.1 InterPro IPR004843; KEGG: mxa:MXAN_1444 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: uncharacterized protein; IMG reference gene:2504919220; metallophosphoesterase 414590 10578832 Trebr_0355 Treponema brennaborense DSM 12168 metallophosphoesterase YP_004438933.1 412827 D 906968 CDS YP_004438934.1 332297012 10578833 414675..415688 1 NC_015500.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: cyn:Cyan7425_0828 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6; SPTR: DNA (Cytosine-5-)-methyltransferase; IMG reference gene:2504919221; PFAM: DNA methylase; DNA methylase N-4/N-6 domain-containing protein 415688 10578833 Trebr_0356 Treponema brennaborense DSM 12168 DNA methylase N-4/N-6 domain-containing protein YP_004438934.1 414675 D 906968 CDS YP_004438935.1 332297013 10578834 complement(415719..416567) 1 NC_015500.1 COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: gbm:Gbem_0725 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504919222; PFAM: ABC transporter; Phosphonate-transporting ATPase 416567 10578834 Trebr_0357 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004438935.1 415719 R 906968 CDS YP_004438936.1 332297014 10578835 complement(416567..417544) 1 NC_015500.1 COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: ssm:Spirs_2323 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504919223; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 417544 10578835 Trebr_0358 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438936.1 416567 R 906968 CDS YP_004438937.1 332297015 10578836 complement(418018..419022) 1 NC_015500.1 COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: gsu:GSU0210 hypothetical protein; PFAM: ABC transporter substrate binding protein; SPTR: ABC transporter, periplasmic solute-binding protein; IMG reference gene:2504919224; PFAM: ABC transporter substrate binding protein; ABC transporter substrate-binding protein 419022 10578836 Trebr_0359 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004438937.1 418018 R 906968 CDS YP_004438938.1 332297016 10578837 complement(419124..419426) 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE0440 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; IMG reference gene:2504919225; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 419426 10578837 Trebr_0360 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004438938.1 419124 R 906968 CDS YP_004438939.1 332297017 10578838 419566..419913 1 NC_015500.1 IMG reference gene:2504919226; hypothetical protein 419913 10578838 Trebr_0361 Treponema brennaborense DSM 12168 hypothetical protein YP_004438939.1 419566 D 906968 CDS YP_004438940.1 332297018 10578839 419944..420585 1 NC_015500.1 IMG reference gene:2504919227; hypothetical protein 420585 10578839 Trebr_0362 Treponema brennaborense DSM 12168 hypothetical protein YP_004438940.1 419944 D 906968 CDS YP_004438941.1 332297019 10578840 complement(420677..422014) 1 NC_015500.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: tde:TDE0102 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; IMG reference gene:2504919228; PFAM: Cyclic nucleotide-binding domain; CarD family transcriptional regulator 422014 10578840 Trebr_0363 Treponema brennaborense DSM 12168 CarD family transcriptional regulator YP_004438941.1 420677 R 906968 CDS YP_004438942.1 332297020 10578841 422198..424114 1 NC_015500.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001:IPR001650:IPR006935; KEGG: tde:TDE2721 helicase domain-containing protein; PFAM: DNA/RNA helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Helicase domain protein; IMG reference gene:2504919229; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; TIGRFAM: DNA repair helicase rad25; helicase domain-containing protein 424114 10578841 Trebr_0364 Treponema brennaborense DSM 12168 helicase domain-containing protein YP_004438942.1 422198 D 906968 CDS YP_004438943.1 332297021 10578842 424111..426507 1 NC_015500.1 KEGG: tde:TDE0193 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919230; hypothetical protein 426507 10578842 Trebr_0365 Treponema brennaborense DSM 12168 hypothetical protein YP_004438943.1 424111 D 906968 CDS YP_004438944.1 332297022 10578843 426531..427325 1 NC_015500.1 COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: eck:EC55989_3790 phosphoglycolate phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Phosphoglycolate phosphatase; IMG reference gene:2504919231; PFAM: haloacid dehalogenase-like hydrolase; Phosphoglycolate phosphatase 427325 10578843 Trebr_0366 Treponema brennaborense DSM 12168 Phosphoglycolate phosphatase YP_004438944.1 426531 D 906968 CDS YP_004438945.1 332297023 10578844 427667..427861 1 NC_015500.1 IMG reference gene:2504919232; hypothetical protein 427861 10578844 Trebr_0367 Treponema brennaborense DSM 12168 hypothetical protein YP_004438945.1 427667 D 906968 CDS YP_004438946.1 332297024 10578849 433198..433620 1 NC_015500.1 KEGG: cpy:Cphy_1853 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919237; PFAM: Protein of unknown function (DUF2871); hypothetical protein 433620 10578849 Trebr_0368 Treponema brennaborense DSM 12168 hypothetical protein YP_004438946.1 433198 D 906968 CDS YP_004438947.1 332297025 10578850 complement(433763..434803) 1 NC_015500.1 COGs: COG0208 Ribonucleotide reductase beta subunit; InterPro IPR000358; KEGG: bvu:BVU_3097 ribonucleotide-diphosphate reductase subunit beta; PFAM: Ribonucleotide reductase; SPTR: Ribonucleoside-diphosphate reductase, beta subunit; IMG reference gene:2504919238; PFAM: Ribonucleotide reductase, small chain; ribonucleotide reductase 434803 10578850 Trebr_0369 Treponema brennaborense DSM 12168 ribonucleotide reductase YP_004438947.1 433763 R 906968 CDS YP_004438948.1 332297026 10578851 complement(434945..437479) 1 NC_015500.1 InterPro IPR005144:IPR013509:IPR000788:IPR013346; KEGG: bfs:BF2713 ribonucleotide-diphosphate reductase subunit alpha; PFAM: Ribonucleotide reductase large subunit, C-terminal; Ribonucleotide reductase large subunit, N-terminal; ATP-cone; PRIAM: Ribonucleoside-diphosphate reductase; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: Ribonucleoside-diphosphate reductase, alpha subunit; IMG reference gene:2504919239; PFAM: Ribonucleotide reductase, all-alpha domain; ATP cone domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; ribonucleoside-diphosphate reductase subunit alpha 437479 10578851 Trebr_0370 Treponema brennaborense DSM 12168 ribonucleoside-diphosphate reductase subunit alpha YP_004438948.1 434945 R 906968 CDS YP_004438949.1 332297027 10578852 complement(437606..438793) 1 NC_015500.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: cni:Calni_1180 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2504919240; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 438793 10578852 Trebr_0371 Treponema brennaborense DSM 12168 dTDP-glucose 4,6-dehydratase YP_004438949.1 437606 R 906968 CDS YP_004438950.1 332297028 10578853 complement(438806..439738) 1 NC_015500.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: cni:Calni_1181 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; IMG reference gene:2504919241; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 439738 10578853 Trebr_0372 Treponema brennaborense DSM 12168 dTDP-4-dehydrorhamnose reductase YP_004438950.1 438806 R 906968 CDS YP_004438951.1 332297029 10578854 complement(439841..440422) 1 NC_015500.1 COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: bhy:BHWA1_02694 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related; IMG reference gene:2504919242; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose 3,5-epimerase 440422 10578854 Trebr_0373 Treponema brennaborense DSM 12168 dTDP-4-dehydrorhamnose 3,5-epimerase YP_004438951.1 439841 R 906968 CDS YP_004438952.1 332297030 10578855 complement(440431..441306) 1 NC_015500.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005907; KEGG: tde:TDE1440 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form; IMG reference gene:2504919243; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form; glucose-1-phosphate thymidylyltransferase 441306 10578855 Trebr_0374 Treponema brennaborense DSM 12168 glucose-1-phosphate thymidylyltransferase YP_004438952.1 440431 R 906968 CDS YP_004438953.1 332297031 10578856 complement(441452..442384) 1 NC_015500.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: ssm:Spirs_4300 ParB-like partition protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504919244; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; parB-like partition protein 442384 10578856 Trebr_0375 Treponema brennaborense DSM 12168 parB-like partition protein YP_004438953.1 441452 R 906968 CDS YP_004438954.1 332297032 10578857 complement(442377..443132) 1 NC_015500.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tde:TDE0607 ParA family ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: ParA family ATPase; IMG reference gene:2504919245; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; Cobyrinic acid ac-diamide synthase 443132 10578857 Trebr_0376 Treponema brennaborense DSM 12168 Cobyrinic acid ac-diamide synthase YP_004438954.1 442377 R 906968 CDS YP_004438955.1 332297033 10578858 443219..443563 1 NC_015500.1 KEGG: sta:STHERM_c13800 hypothetical protein; SPTR: DRTGG domain protein; IMG reference gene:2504919246; PFAM: DRTGG domain; hypothetical protein 443563 10578858 Trebr_0377 Treponema brennaborense DSM 12168 hypothetical protein YP_004438955.1 443219 D 906968 CDS YP_004438956.1 332297034 10578859 443581..444960 1 NC_015500.1 KEGG: csh:Closa_1889 hypothetical protein; SPTR: Methyltransferase; IMG reference gene:2504919247; hypothetical protein 444960 10578859 Trebr_0378 Treponema brennaborense DSM 12168 hypothetical protein YP_004438956.1 443581 D 906968 CDS YP_004438957.1 332297035 10578860 444957..445604 1 NC_015500.1 COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: cac:CA_C2496 HAD family phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2504919248; PFAM: haloacid dehalogenase-like hydrolase; HAD-superfamily hydrolase 445604 10578860 Trebr_0379 Treponema brennaborense DSM 12168 HAD-superfamily hydrolase YP_004438957.1 444957 D 906968 CDS YP_004438958.1 332297036 10578861 445988..457156 1 NC_015500.1 KEGG: sta:STHERM_c01520 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919249; hypothetical protein 457156 10578861 Trebr_0380 Treponema brennaborense DSM 12168 hypothetical protein YP_004438958.1 445988 D 906968 CDS YP_004438959.1 332297037 10578862 457156..462426 1 NC_015500.1 KEGG: tde:TDE2709 BNR domain-containing protein; SPTR: BNR domain protein; IMG reference gene:2504919250; PFAM: Mo-co oxidoreductase dimerisation domain; BNR repeat-containing protein 462426 10578862 Trebr_0381 Treponema brennaborense DSM 12168 BNR repeat-containing protein YP_004438959.1 457156 D 906968 CDS YP_004438960.1 332297038 10578863 complement(462397..463557) 1 NC_015500.1 IMG reference gene:2504919251; hypothetical protein 463557 10578863 Trebr_0382 Treponema brennaborense DSM 12168 hypothetical protein YP_004438960.1 462397 R 906968 CDS YP_004438961.1 332297039 10578864 463640..464746 1 NC_015500.1 IMG reference gene:2504919252; hypothetical protein 464746 10578864 Trebr_0383 Treponema brennaborense DSM 12168 hypothetical protein YP_004438961.1 463640 D 906968 CDS YP_004438962.1 332297040 10578865 464739..466163 1 NC_015500.1 COGs: COG2206 HD-GYP domain; KEGG: gme:Gmet_1991 GAF sensor signal transduction histidine kinase; SPTR: GAF sensor signal transduction histidine kinase; IMG reference gene:2504919253; metal dependent phosphohydrolase 466163 10578865 Trebr_0384 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004438962.1 464739 D 906968 CDS YP_004438963.1 332297041 10578867 466497..467195 1 NC_015500.1 KEGG: cpy:Cphy_1854 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919255; hypothetical protein 467195 10578867 Trebr_0385 Treponema brennaborense DSM 12168 hypothetical protein YP_004438963.1 466497 D 906968 CDS YP_004438964.1 332297042 10578868 467280..468794 1 NC_015500.1 COGs: COG0753 Catalase; InterPro IPR018028:IPR010582; KEGG: mla:Mlab_1574 hypothetical protein; PFAM: Catalase related subgroup; Catalase-related immune responsive; PRIAM: Catalase; SPTR: Catalase; IMG reference gene:2504919256; PFAM: Catalase; Catalase-related immune-responsive; catalase 468794 10578868 Trebr_0386 Treponema brennaborense DSM 12168 catalase YP_004438964.1 467280 D 906968 CDS YP_004438965.1 332297043 10578869 complement(468899..470278) 1 NC_015500.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: elm:ELI_3758 pyridine nucleotide-disulfide oxidoreductase family protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Possible mercury(II) reductase; IMG reference gene:2504919257; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Dihydrolipoyl dehydrogenase 470278 10578869 Trebr_0387 Treponema brennaborense DSM 12168 Dihydrolipoyl dehydrogenase YP_004438965.1 468899 R 906968 CDS YP_004438966.1 332297044 10578870 complement(470297..470719) 1 NC_015500.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: ele:Elen_0624 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcriptional regulator, Rrf2; SPTR: uncharacterized protein; IMG reference gene:2504919258; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein; asnc family transcriptional regulator 470719 10578870 Trebr_0388 Treponema brennaborense DSM 12168 asnc family transcriptional regulator YP_004438966.1 470297 R 906968 CDS YP_004438967.1 332297045 10578871 complement(470723..471115) 1 NC_015500.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: bpb:bpr_I2677 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain-containing protein; IMG reference gene:2504919259; PFAM: Rhodanese-like domain; rhodanese-like protein 471115 10578871 Trebr_0389 Treponema brennaborense DSM 12168 rhodanese-like protein YP_004438967.1 470723 R 906968 CDS YP_004438968.1 332297046 10578872 complement(471230..472216) 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: tmt:Tmath_0363 transcriptional regulator, MarR family; PFAM: Carbohydrate/purine kinase; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504919260; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 472216 10578872 Trebr_0390 Treponema brennaborense DSM 12168 PfkB domain-containing protein YP_004438968.1 471230 R 906968 CDS YP_004438969.1 332297047 10578873 complement(472203..472796) 1 NC_015500.1 KEGG: mac:MA2063 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504919261; hypothetical protein 472796 10578873 Trebr_0391 Treponema brennaborense DSM 12168 hypothetical protein YP_004438969.1 472203 R 906968 CDS YP_004438970.1 332297048 10578874 472886..473728 1 NC_015500.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel; IMG reference gene:2504919262; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase domain-containing protein TIM barrel 473728 10578874 Trebr_0392 Treponema brennaborense DSM 12168 xylose isomerase domain-containing protein TIM barrel YP_004438970.1 472886 D 906968 CDS YP_004438971.1 332297049 10578875 473799..476375 1 NC_015500.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR013027:IPR004099:IPR001455; KEGG: cpy:Cphy_3470 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SirA-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: uncharacterized protein; IMG reference gene:2504919263; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; CoA-disulfide reductase 476375 10578875 Trebr_0393 Treponema brennaborense DSM 12168 CoA-disulfide reductase YP_004438971.1 473799 D 906968 CDS YP_004438972.1 332297050 10578876 complement(476454..477134) 1 NC_015500.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001808:IPR000595; KEGG: cdf:CD0629 transcriptional regulator; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; SPTR: Possible cAMP regulatory protein; IMG reference gene:2504919264; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; CarD family transcriptional regulator 477134 10578876 Trebr_0394 Treponema brennaborense DSM 12168 CarD family transcriptional regulator YP_004438972.1 476454 R 906968 CDS YP_004438973.1 332297051 10578877 complement(477124..478056) 1 NC_015500.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: csh:Closa_1863 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919265; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 478056 10578877 Trebr_0395 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004438973.1 477124 R 906968 CDS YP_004438974.1 332297052 10578878 complement(478121..480637) 1 NC_015500.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003660:IPR003607:IPR006674; KEGG: bse:Bsel_0662 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; HAMP linker domain; SMART: Metal-dependent phosphohydrolase, HD region; HAMP linker domain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504919266; PFAM: HD domain; metal dependent phosphohydrolase 480637 10578878 Trebr_0396 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004438974.1 478121 R 906968 CDS YP_004438975.1 332297053 10578879 480825..482321 1 NC_015500.1 COGs: COG0554 Glycerol kinase; HAMAP: Glycerol kinase; InterPro IPR018484:IPR018485:IPR005999; KEGG: cbe:Cbei_4509 glycerol kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Glycerol kinase; SPTR: Glycerol kinase; TIGRFAM: Glycerol kinase; IMG reference gene:2504919267; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; Glycerol kinase 482321 10578879 Trebr_0397 Treponema brennaborense DSM 12168 Glycerol kinase YP_004438975.1 480825 D 906968 CDS YP_004438976.1 332297054 10578880 482568..484655 1 NC_015500.1 COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: cth:Cthe_0196 glutamine synthetase, catalytic region; PFAM: Glutamine synthetase, catalytic region; SPTR: uncharacterized protein; IMG reference gene:2504919268; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal; glutamine synthetase catalytic subunit 484655 10578880 Trebr_0398 Treponema brennaborense DSM 12168 glutamine synthetase catalytic subunit YP_004438976.1 482568 D 906968 CDS YP_004438977.1 332297055 10578881 484984..486726 1 NC_015500.1 COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR002187; KEGG: eel:EUBELI_00740 guanylate cyclase; PFAM: Ammonium transporter; Nitrogen regulatory protein PII; SPTR: Ammonium transporter; TIGRFAM: Ammonium transporter; IMG reference gene:2504919269; PFAM: Ammonium Transporter Family; Nitrogen regulatory protein P-II; TIGRFAM: ammonium transporter; ammonium transporter 486726 10578881 Trebr_0399 Treponema brennaborense DSM 12168 ammonium transporter YP_004438977.1 484984 D 906968 CDS YP_004438978.1 332297056 10578882 486850..489135 1 NC_015500.1 COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: cdc:CD196_2722 signaling protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: signaling protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919270; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase/phosphodiesterase 489135 10578882 Trebr_0400 Treponema brennaborense DSM 12168 diguanylate cyclase/phosphodiesterase YP_004438978.1 486850 D 906968 CDS YP_004438979.1 332297057 10578883 complement(489244..490590) 1 NC_015500.1 COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: cno:NT01CX_2418 phosphoribosylformylglycinamidine synthase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504919271; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Phosphoribosylamine--glycine ligase 490590 10578883 Trebr_0401 Treponema brennaborense DSM 12168 Phosphoribosylamine--glycine ligase YP_004438979.1 489244 R 906968 CDS YP_004438980.1 332297058 10578886 complement(495508..496221) 1 NC_015500.1 KEGG: csh:Closa_4247 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919274; hypothetical protein 496221 10578886 Trebr_0404 Treponema brennaborense DSM 12168 hypothetical protein YP_004438980.1 495508 R 906968 CDS YP_004438981.1 332297059 10578887 complement(496208..497596) 1 NC_015500.1 KEGG: csh:Closa_4248 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919275; hypothetical protein 497596 10578887 Trebr_0405 Treponema brennaborense DSM 12168 hypothetical protein YP_004438981.1 496208 R 906968 CDS YP_004438982.1 332297060 10578888 complement(497882..498289) 1 NC_015500.1 IMG reference gene:2504919276; hypothetical protein 498289 10578888 Trebr_0406 Treponema brennaborense DSM 12168 hypothetical protein YP_004438982.1 497882 R 906968 CDS YP_004438983.1 332297061 10578889 complement(498286..499800) 1 NC_015500.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: ddd:Dda3937_03601 radical SAM domain heme biosynthesis protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain heme biosynthesis protein; IMG reference gene:2504919277; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain; Radical SAM domain protein 499800 10578889 Trebr_0407 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004438983.1 498286 R 906968 CDS YP_004438984.1 332297062 10578890 complement(500002..500220) 1 NC_015500.1 IMG reference gene:2504919278; hypothetical protein 500220 10578890 Trebr_0408 Treponema brennaborense DSM 12168 hypothetical protein YP_004438984.1 500002 R 906968 CDS YP_004438985.1 332297063 10578891 complement(500238..501461) 1 NC_015500.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: lci:LCK_00904 restriction-modification enzyme type I S subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: type-I specificity determinant subunit; IMG reference gene:2504919279; PFAM: Type I restriction modification DNA specificity domain; restriction modification system DNA specificity domain-containing protein 501461 10578891 Trebr_0409 Treponema brennaborense DSM 12168 restriction modification system DNA specificity domain-containing protein YP_004438985.1 500238 R 906968 CDS YP_004438986.1 332297064 10578892 complement(501448..502056) 1 NC_015500.1 KEGG: plt:Plut_0642 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919280; PFAM: BRO family, N-terminal domain; hypothetical protein 502056 10578892 Trebr_0410 Treponema brennaborense DSM 12168 hypothetical protein YP_004438986.1 501448 R 906968 CDS YP_004438987.1 332297065 10578893 complement(502056..503138) 1 NC_015500.1 COGs: COG3943 Virulence protein; KEGG: chu:CHU_3353 virulence protein; SPTR: uncharacterized protein; IMG reference gene:2504919281; virulence protein 503138 10578893 Trebr_0411 Treponema brennaborense DSM 12168 virulence protein YP_004438987.1 502056 R 906968 CDS YP_004438988.1 332297066 10578894 complement(503201..505801) 1 NC_015500.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR004546; KEGG: hse:Hsero_4561 type I restriction-modification system methyltransferase subunit; PFAM: DNA methylase, adenine-specific; SPTR: Type I restriction-modification system methyltransferase subunit protein; TIGRFAM: Restriction endonuclease, type I, EcoRI, M subunit; IMG reference gene:2504919282; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM); type I restriction-modification system, M subunit 505801 10578894 Trebr_0412 Treponema brennaborense DSM 12168 type I restriction-modification system, M subunit YP_004438988.1 503201 R 906968 CDS YP_004438989.1 332297067 10578896 507195..508748 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: toc:Toce_1077 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919284; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 508748 10578896 Trebr_0414 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004438989.1 507195 D 906968 CDS YP_004438990.1 332297068 10578897 complement(508792..510972) 1 NC_015500.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153:IPR002178; KEGG: ssm:Spirs_3913 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504919285; PFAM: Sodium/hydrogen exchanger family; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; sodium/hydrogen exchanger 510972 10578897 Trebr_0415 Treponema brennaborense DSM 12168 sodium/hydrogen exchanger YP_004438990.1 508792 R 906968 CDS YP_004438991.1 332297069 10578898 complement(511088..512434) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: tde:TDE0621 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919286; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 512434 10578898 Trebr_0416 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004438991.1 511088 R 906968 CDS YP_004438992.1 332297070 10578899 complement(512458..513819) 1 NC_015500.1 COGs: COG2848 conserved hypothetical protein; HAMAP: UPF0210 protein; InterPro IPR007841; KEGG: amt:Amet_3399 hypothetical protein; PFAM: Protein of unknown function DUF711; SPTR: UPF0210 protein Amet_3399; IMG reference gene:2504919287; PFAM: Uncharacterized ACR (DUF711); hypothetical protein 513819 10578899 Trebr_0417 Treponema brennaborense DSM 12168 hypothetical protein YP_004438992.1 512458 R 906968 CDS YP_004438993.1 332297071 10578900 complement(513956..515344) 1 NC_015500.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR003593:IPR004504; KEGG: tde:TDE2517 DNA repair protein RadA; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; IMG reference gene:2504919288; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA; DNA repair protein RadA 515344 10578900 Trebr_0418 Treponema brennaborense DSM 12168 DNA repair protein RadA YP_004438993.1 513956 R 906968 CDS YP_004438994.1 332297072 10578901 complement(515360..515740) 1 NC_015500.1 KEGG: sta:STHERM_c21820 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919289; PFAM: Protein of unknown function (DUF1312); hypothetical protein 515740 10578901 Trebr_0419 Treponema brennaborense DSM 12168 hypothetical protein YP_004438994.1 515360 R 906968 CDS YP_004438995.1 332297073 10578902 complement(515737..516975) 1 NC_015500.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ssm:Spirs_1197 ROK family protein; PFAM: ROK; SPTR: ROK family protein; IMG reference gene:2504919290; PFAM: ROK family; ROK family protein 516975 10578902 Trebr_0420 Treponema brennaborense DSM 12168 ROK family protein YP_004438995.1 515737 R 906968 CDS YP_004438996.1 332297074 10578903 517105..518118 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c15050 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulatory protein; IMG reference gene:2504919291; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 518118 10578903 Trebr_0421 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004438996.1 517105 D 906968 CDS YP_004438997.1 332297075 10578904 518216..519523 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c15040 alpha-glucosides-binding periplasmic protein AglE precursor; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504919292; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 519523 10578904 Trebr_0422 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004438997.1 518216 D 906968 CDS YP_004438998.1 332297076 10578905 519613..520692 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c15030 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Transporter; IMG reference gene:2504919293; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 520692 10578905 Trebr_0423 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438998.1 519613 D 906968 CDS YP_004438999.1 332297077 10578906 520692..521600 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c15020 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Transporter; IMG reference gene:2504919294; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 521600 10578906 Trebr_0424 Treponema brennaborense DSM 12168 ABC transporter permease YP_004438999.1 520692 D 906968 CDS YP_004439000.1 332297078 10578907 521608..522627 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: thx:Thet_1794 PfkB domain-containing protein; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: uncharacterized protein; IMG reference gene:2504919295; PFAM: pfkB family carbohydrate kinase; fructokinase 522627 10578907 Trebr_0425 Treponema brennaborense DSM 12168 fructokinase YP_004439000.1 521608 D 906968 CDS YP_004439001.1 332297079 10578908 522624..525806 1 NC_015500.1 COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterProIPR005196:IPR005195:IPR005194:IPR005834:IPR 010972:IPR010976:IPR006402; KEGG: ssm:Spirs_3639 beta-phosphoglucomutase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; Glycoside hydrolase, family 65, C-terminal; Haloacid dehalogenase-like hydrolase; PRIAM: Kojibiose phosphorylase., Beta-phosphoglucomutase; SPTR: Beta-phosphoglucomutase; TIGRFAM: Beta-phosphoglucomutase; Beta-phosphoglucomutase hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504919296; PFAM: Glycosyl hydrolase family 65, C-terminal domain; haloacid dehalogenase-like hydrolase; Glycosyl hydrolase family 65, N-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; TIGRFAM: beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphoglucomutase 525806 10578908 Trebr_0426 Treponema brennaborense DSM 12168 beta-phosphoglucomutase YP_004439001.1 522624 D 906968 CDS YP_004439002.1 332297080 10578909 complement(526016..526870) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_1398 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504919297; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 526870 10578909 Trebr_0427 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439002.1 526016 R 906968 CDS YP_004439003.1 332297081 10578910 complement(526872..527771) 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_2122 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504919298; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 527771 10578910 Trebr_0428 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439003.1 526872 R 906968 CDS YP_004439004.1 332297082 10578911 complement(527882..529225) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c02610 sugar ABC transporter sugar-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504919299; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 529225 10578911 Trebr_0429 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004439004.1 527882 R 906968 CDS YP_004439005.1 332297083 10578912 529644..530771 1 NC_015500.1 IMG reference gene:2504919300; hypothetical protein 530771 10578912 Trebr_0430 Treponema brennaborense DSM 12168 hypothetical protein YP_004439005.1 529644 D 906968 CDS YP_004439006.1 332297084 10578913 complement(530942..532246) 1 NC_015500.1 KEGG: chu:CHU_3514 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919301; hypothetical protein 532246 10578913 Trebr_0431 Treponema brennaborense DSM 12168 hypothetical protein YP_004439006.1 530942 R 906968 CDS YP_004439007.1 332297085 10578914 complement(532236..533366) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cth:Cthe_1523 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1; IMG reference gene:2504919302; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 533366 10578914 Trebr_0432 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004439007.1 532236 R 906968 CDS YP_004439008.1 332297086 10578915 533528..535507 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR011623; KEGG: lic:LIC10245 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Diverse 7TM receptor, transmembrane region; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase; IMG reference gene:2504919303; PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; adenylate/guanylate cyclase 535507 10578915 Trebr_0433 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase YP_004439008.1 533528 D 906968 CDS YP_004439009.1 332297087 10578916 535671..536693 1 NC_015500.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: btl:BALH_2820 transporter; PFAM: Divalent ion symporter; SPTR: Citrate transporter; IMG reference gene:2504919304; PFAM: Citrate transporter; citrate transporter 536693 10578916 Trebr_0434 Treponema brennaborense DSM 12168 citrate transporter YP_004439009.1 535671 D 906968 CDS YP_004439010.1 332297088 10578917 536697..537458 1 NC_015500.1 COGs: COG3148 conserved hypothetical protein; InterPro IPR005636; KEGG: ote:Oter_3739 DTW domain-containing protein; PFAM: DTW; SPTR: DTW domain containing protein; IMG reference gene:2504919305; PFAM: DTW domain; DTW domain containing protein 537458 10578917 Trebr_0435 Treponema brennaborense DSM 12168 DTW domain containing protein YP_004439010.1 536697 D 906968 CDS YP_004439011.1 332297089 10578918 complement(537433..538308) 1 NC_015500.1 IMG reference gene:2504919306; hypothetical protein 538308 10578918 Trebr_0436 Treponema brennaborense DSM 12168 hypothetical protein YP_004439011.1 537433 R 906968 CDS YP_004439012.1 332297090 10578919 538585..539460 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504919307; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 539460 10578919 Trebr_0437 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004439012.1 538585 D 906968 CDS YP_004439013.1 332297091 10578920 complement(539581..540612) 1 NC_015500.1 InterPro IPR001173; KEGG: pru:PRU_1336 group 2 family glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyltransferase; IMG reference gene:2504919308; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 540612 10578920 Trebr_0438 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004439013.1 539581 R 906968 CDS YP_004439014.1 332297092 10578921 complement(540623..541753) 1 NC_015500.1 KEGG: oih:OB1130 hypothetical protein; SPTR: WbsX; IMG reference gene:2504919309; hypothetical protein 541753 10578921 Trebr_0439 Treponema brennaborense DSM 12168 hypothetical protein YP_004439014.1 540623 R 906968 CDS YP_004439015.1 332297093 10578922 complement(541750..542931) 1 NC_015500.1 KEGG: pdi:BDI_0302 lipopolysaccharide biosynthesis related polysaccharide polymerase; SPTR: Predicted protein; IMG reference gene:2504919310; hypothetical protein 542931 10578922 Trebr_0440 Treponema brennaborense DSM 12168 hypothetical protein YP_004439015.1 541750 R 906968 CDS YP_004439016.1 332297094 10578923 complement(542970..544085) 1 NC_015500.1 KEGG: mma:MM_2213 glycosyltransferase; SPTR: ORF12 protein; IMG reference gene:2504919311; PFAM: Glycosyl transferases group 1; hypothetical protein 544085 10578923 Trebr_0441 Treponema brennaborense DSM 12168 hypothetical protein YP_004439016.1 542970 R 906968 CDS YP_004439017.1 332297095 10578924 complement(544072..545202) 1 NC_015500.1 KEGG: bth:BT_0042 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919312; PFAM: Polysaccharide pyruvyl transferase; hypothetical protein 545202 10578924 Trebr_0442 Treponema brennaborense DSM 12168 hypothetical protein YP_004439017.1 544072 R 906968 CDS YP_004439018.1 332297096 10578925 complement(545204..546940) 1 NC_015500.1 COGs: COG1165 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase; InterPro IPR012001; KEGG: slo:Shew_1408 thiamine pyrophosphate binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; SPTR: 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; IMG reference gene:2504919313; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate TPP-binding domain-containing protein 546940 10578925 Trebr_0443 Treponema brennaborense DSM 12168 thiamine pyrophosphate TPP-binding domain-containing protein YP_004439018.1 545204 R 906968 CDS YP_004439019.1 332297097 10578926 complement(546959..548017) 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD dependent epimerase/dehydratase family protein; IMG reference gene:2504919314; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 548017 10578926 Trebr_0444 Treponema brennaborense DSM 12168 NAD-dependent epimerase/dehydratase YP_004439019.1 546959 R 906968 CDS YP_004439020.1 332297098 10578927 complement(548014..549297) 1 NC_015500.1 KEGG: ppd:Ppro_2756 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919315; hypothetical protein 549297 10578927 Trebr_0445 Treponema brennaborense DSM 12168 hypothetical protein YP_004439020.1 548014 R 906968 CDS YP_004439021.1 332297099 10578928 complement(549349..550956) 1 NC_015500.1 InterPro IPR002797; KEGG: bvu:BVU_2391 transmembrane protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Conserved hypothetical transmembrane protein; transmembrane protein; IMG reference gene:2504919316; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 550956 10578928 Trebr_0446 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004439021.1 549349 R 906968 CDS YP_004439022.1 332297100 10578929 551268..551651 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504919317; PFAM: Bacteriophage CI repressor helix-turn-helix domain; helix-turn-helix domain-containing protein 551651 10578929 Trebr_0447 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439022.1 551268 D 906968 CDS YP_004439023.1 332297101 10578930 complement(551688..552365) 1 NC_015500.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: tpp:TPASS_0158 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Pyrimidine 5'-nucleotidase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504919318; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; pyrimidine 5'-nucleotidase; HAD-superfamily hydrolase 552365 10578930 Trebr_0448 Treponema brennaborense DSM 12168 HAD-superfamily hydrolase YP_004439023.1 551688 R 906968 CDS YP_004439024.1 332297102 10578931 complement(552368..553930) 1 NC_015500.1 COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: ssm:Spirs_4048 RNA polymerase, sigma 54 subunit, RpoN; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma factor 54; IMG reference gene:2504919319; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor; RNA polymerase sigma 54 subunit RpoN 553930 10578931 Trebr_0449 Treponema brennaborense DSM 12168 RNA polymerase sigma 54 subunit RpoN YP_004439024.1 552368 R 906968 CDS YP_004439025.1 332297103 10578932 553988..555367 1 NC_015500.1 InterPro IPR008323; KEGG: cth:Cthe_3196 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Uncharacterized conserved protein UCP033563; IMG reference gene:2504919320; PFAM: Protein of unknown function (DUF1015); hypothetical protein 555367 10578932 Trebr_0450 Treponema brennaborense DSM 12168 hypothetical protein YP_004439025.1 553988 D 906968 CDS YP_004439026.1 332297104 10578934 complement(555637..557172) 1 NC_015500.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR000523:IPR004482; KEGG: tde:TDE1995 magnesium chelatase family protein; PFAM: Magnesium chelatase, ChlI subunit; SPTR: Magnesium chelatase family protein; TIGRFAM: Mg chelatase-related protein; IMG reference gene:2504919322; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein; Mg chelatase subunit ChlI 557172 10578934 Trebr_0451 Treponema brennaborense DSM 12168 Mg chelatase subunit ChlI YP_004439026.1 555637 R 906968 CDS YP_004439027.1 332297105 10578935 557319..558359 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ssm:Spirs_0925 transcriptional regulator, LacI family; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504919323; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 558359 10578935 Trebr_0452 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004439027.1 557319 D 906968 CDS YP_004439028.1 332297106 10578936 complement(558431..559285) 1 NC_015500.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141:IPR004013; KEGG: tde:TDE2618 phosphotransferase domain-containing protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; IMG reference gene:2504919324; PFAM: PHP domain; PHP domain-containing protein 559285 10578936 Trebr_0453 Treponema brennaborense DSM 12168 PHP domain-containing protein YP_004439028.1 558431 R 906968 CDS YP_004439029.1 332297107 10578937 559364..560608 1 NC_015500.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; IMG reference gene:2504919325; PFAM: Cyclic nucleotide-binding domain; CarD family transcriptional regulator 560608 10578937 Trebr_0454 Treponema brennaborense DSM 12168 CarD family transcriptional regulator YP_004439029.1 559364 D 906968 CDS YP_004439030.1 332297108 10578939 560893..561789 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: cpi:Cpin_3596 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; IMG reference gene:2504919327; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; AraC family transcriptional regulator 561789 10578939 Trebr_0455 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439030.1 560893 D 906968 CDS YP_004439031.1 332297109 10578940 561894..564008 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE2549 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919328; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 564008 10578940 Trebr_0456 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439031.1 561894 D 906968 CDS YP_004439032.1 332297110 10578941 564065..565594 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: gsu:GSU0683 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer, ; IMG reference gene:2504919329; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 565594 10578941 Trebr_0457 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439032.1 564065 D 906968 CDS YP_004439033.1 332297111 10578942 565604..566614 1 NC_015500.1 IMG reference gene:2504919330; hypothetical protein 566614 10578942 Trebr_0458 Treponema brennaborense DSM 12168 hypothetical protein YP_004439033.1 565604 D 906968 CDS YP_004439034.1 332297112 10578943 566611..567342 1 NC_015500.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: response regulator; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Response regulator containing a CheY-like receiver domain and an HD-GYP domain; IMG reference gene:2504919331; PFAM: HD domain; metal dependent phosphohydrolase 567342 10578943 Trebr_0459 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004439034.1 566611 D 906968 CDS YP_004439035.1 332297113 10578944 567518..569020 1 NC_015500.1 COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006153:IPR006037; KEGG: swo:Swol_1590 potassium/proton antiporter; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; SPTR: Na+/H+ antiporter; IMG reference gene:2504919332; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain; sodium/hydrogen exchanger 569020 10578944 Trebr_0460 Treponema brennaborense DSM 12168 sodium/hydrogen exchanger YP_004439035.1 567518 D 906968 CDS YP_004439036.1 332297114 10578945 complement(569050..571011) 1 NC_015500.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: dap:Dacet_0977 ABC transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504919333; PFAM: ABC transporter; ABC transporter 571011 10578945 Trebr_0461 Treponema brennaborense DSM 12168 ABC transporter YP_004439036.1 569050 R 906968 CDS YP_004439037.1 332297115 10578946 complement(571111..571908) 1 NC_015500.1 COGs: COG0263 Glutamate 5-kinase; HAMAP: Glutamate 5-kinase; InterPro IPR001048:IPR005715; KEGG: bpb:bpr_I1299 glutamate 5-kinase ProB; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Glutamate 5-kinase 2; TIGRFAM: Glutamate 5-kinase, ProB-related; IMG reference gene:2504919334; PFAM: Amino acid kinase family; TIGRFAM: glutamate 5-kinase; Glutamate 5-kinase 571908 10578946 Trebr_0462 Treponema brennaborense DSM 12168 Glutamate 5-kinase YP_004439037.1 571111 R 906968 CDS YP_004439038.1 332297116 10578947 572000..572869 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: str:Sterm_3036 transcriptional regulator, LysR family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: uncharacterized protein; IMG reference gene:2504919335; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; LysR family transcriptional regulator 572869 10578947 Trebr_0463 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004439038.1 572000 D 906968 CDS YP_004439039.1 332297117 10578948 572917..573954 1 NC_015500.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: bpb:bpr_I1785 hypothetical protein; PFAM: Protein of unknown function DUF2179; Protein of unknown function DUF161; SPTR: uncharacterized protein; IMG reference gene:2504919336; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179); hypothetical protein 573954 10578948 Trebr_0464 Treponema brennaborense DSM 12168 hypothetical protein YP_004439039.1 572917 D 906968 CDS YP_004439040.1 332297118 10578949 574016..575749 1 NC_015500.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953:IPR010960; KEGG: ssm:Spirs_3607 flavocytochrome c; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; FMN-binding; PRIAM: Succinate dehydrogenase; SPTR: Flavocytochrome c; TIGRFAM: Flavocytochrome c; IMG reference gene:2504919337; PFAM: FAD binding domain; FMN-binding domain; TIGRFAM: flavocytochrome c; flavocytochrome c 575749 10578949 Trebr_0465 Treponema brennaborense DSM 12168 flavocytochrome c YP_004439040.1 574016 D 906968 CDS YP_004439041.1 332297119 10578950 576055..577083 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ccb:Clocel_3206 transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504919338; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 577083 10578950 Trebr_0466 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004439041.1 576055 D 906968 CDS YP_004439042.1 332297120 10578951 577313..578251 1 NC_015500.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4803 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; IMG reference gene:2504919339; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 578251 10578951 Trebr_0467 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439042.1 577313 D 906968 CDS YP_004439043.1 332297121 10578952 578264..579178 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4804 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family (TC 3.A.1.1.-); IMG reference gene:2504919340; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 579178 10578952 Trebr_0468 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439043.1 578264 D 906968 CDS YP_004439044.1 332297122 10578953 579218..580639 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_6241 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-); IMG reference gene:2504919341; PFAM: Domain of unknown function (DUF3502); Bacterial extracellular solute-binding protein; extracellular solute-binding protein 580639 10578953 Trebr_0469 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004439044.1 579218 D 906968 CDS YP_004439045.1 332297123 10578954 580740..583097 1 NC_015500.1 KEGG: gym:GYMC10_1991 glycoside hydrolase family 38; SPTR: Glycosyl hydrolase family 38 protein; IMG reference gene:2504919342; PFAM: Glycosyl hydrolases family 38 N-terminal domain; glycoside hydrolase family protein 583097 10578954 Trebr_0470 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004439045.1 580740 D 906968 CDS YP_004439046.1 332297124 10578955 583223..585001 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: eel:EUBELI_01593 ATP-binding cassette subfamily B protein; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504919343; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 585001 10578955 Trebr_0471 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004439046.1 583223 D 906968 CDS YP_004439047.1 332297125 10578956 584943..585224 1 NC_015500.1 IMG reference gene:2504919344; hypothetical protein 585224 10578956 Trebr_0472 Treponema brennaborense DSM 12168 hypothetical protein YP_004439047.1 584943 D 906968 CDS YP_004439048.1 332297126 10578957 585286..586956 1 NC_015500.1 COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR003593:IPR003439; KEGG: ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504919345; PFAM: ABC transporter; ABC transporter 586956 10578957 Trebr_0473 Treponema brennaborense DSM 12168 ABC transporter YP_004439048.1 585286 D 906968 CDS YP_004439049.1 332297127 10578958 586953..588068 1 NC_015500.1 COGs: COG3858 glycosyl hydrolase; InterPro IPR011583:IPR001223; KEGG: ttm:Tthe_1075 glycoside hydrolase family 18; PFAM: Glycoside hydrolase, family 18, catalytic domain; SMART: Chitinase II; SPTR: Glycoside hydrolase family 18; IMG reference gene:2504919346; PFAM: Glycosyl hydrolases family 18; glycoside hydrolase family protein 588068 10578958 Trebr_0474 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004439049.1 586953 D 906968 CDS YP_004439050.1 332297128 10578959 588160..589251 1 NC_015500.1 SPTR: Major outer membrane protein; IMG reference gene:2504919347; hypothetical protein 589251 10578959 Trebr_0475 Treponema brennaborense DSM 12168 hypothetical protein YP_004439050.1 588160 D 906968 CDS YP_004439051.1 332297129 10578960 complement(589418..590227) 1 NC_015500.1 InterPro IPR002610; KEGG: ssm:Spirs_3042 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein; IMG reference gene:2504919348; PFAM: Rhomboid family; rhomboid family protein 590227 10578960 Trebr_0476 Treponema brennaborense DSM 12168 rhomboid family protein YP_004439051.1 589418 R 906968 CDS YP_004439052.1 332297130 10578961 complement(590234..591013) 1 NC_015500.1 COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: tde:TDE1734 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Exodeoxyribonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; IMG reference gene:2504919349; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); exodeoxyribonuclease III Xth 591013 10578961 Trebr_0477 Treponema brennaborense DSM 12168 exodeoxyribonuclease III Xth YP_004439052.1 590234 R 906968 CDS YP_004439053.1 332297131 10578962 591270..592574 1 NC_015500.1 COGs: COG0148 Enolase; HAMAP: Enolase; InterPro IPR000941:IPR020811:IPR020810; KEGG: csh:Closa_2449 enolase; PFAM: Enolase, C-terminal; Enolase, N-terminal; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase 2; TIGRFAM: Enolase; IMG reference gene:2504919350; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase; enolase 592574 10578962 Trebr_0478 Treponema brennaborense DSM 12168 enolase YP_004439053.1 591270 D 906968 CDS YP_004439054.1 332297132 10578963 complement(592654..593448) 1 NC_015500.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: lam:LA2_00370 phospho-beta-glycosidase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospho-beta-glycosidase; IMG reference gene:2504919351; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase 593448 10578963 Trebr_0479 Treponema brennaborense DSM 12168 phospholipid/glycerol acyltransferase YP_004439054.1 592654 R 906968 CDS YP_004439055.1 332297133 10578964 complement(593450..594703) 1 NC_015500.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: apv:Apar_0835 glycosyl transferase family 2; SPTR: uncharacterized protein; IMG reference gene:2504919352; PFAM: Glycosyl transferase family 2; hypothetical protein 594703 10578964 Trebr_0480 Treponema brennaborense DSM 12168 hypothetical protein YP_004439055.1 593450 R 906968 CDS YP_004439056.1 332297134 10578965 complement(594707..595555) 1 NC_015500.1 COGs: COG1442 Lipopolysaccharide biosynthesis protein LPS:glycosyltransferase; InterPro IPR002495; KEGG: lcr:LCRIS_00070 lipopolysaccharide biosynthesis glycosyltransferase; PFAM: Glycosyl transferase, family 8; SPTR: Lipopolysaccharide biosynthesis glycosyltransferase; IMG reference gene:2504919353; PFAM: Glycosyl transferase family 8; glycosyl transferase family protein 595555 10578965 Trebr_0481 Treponema brennaborense DSM 12168 glycosyl transferase family protein YP_004439056.1 594707 R 906968 CDS YP_004439057.1 332297135 10578966 complement(595592..596371) 1 NC_015500.1 InterPro IPR002123; KEGG: ljo:LJ0063 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919354; phospholipid/glycerol acyltransferase 596371 10578966 Trebr_0482 Treponema brennaborense DSM 12168 phospholipid/glycerol acyltransferase YP_004439057.1 595592 R 906968 CDS YP_004439058.1 332297136 10578967 596796..597632 1 NC_015500.1 COGs: COG1351 alternative thymidylate synthase; HAMAP: Thymidylate synthase thyX; InterPro IPR003669; KEGG: tde:TDE0311 FAD-dependent thymidylate synthase; PFAM: Thymidylate synthase ThyX; SPTR: Thymidylate synthase thyX; TIGRFAM: Thymidylate synthase ThyX; IMG reference gene:2504919355; PFAM: Thymidylate synthase complementing protein; TIGRFAM: thymidylate synthase, flavin-dependent; thymidylate synthase ThyX 597632 10578967 Trebr_0483 Treponema brennaborense DSM 12168 thymidylate synthase ThyX YP_004439058.1 596796 D 906968 CDS YP_004439059.1 332297137 10578968 complement(597801..599867) 1 NC_015500.1 KEGG: ssm:Spirs_4105 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919356; hypothetical protein 599867 10578968 Trebr_0484 Treponema brennaborense DSM 12168 hypothetical protein YP_004439059.1 597801 R 906968 CDS YP_004439060.1 332297138 10578969 complement(599892..600959) 1 NC_015500.1 KEGG: tde:TDE2551 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919357; PFAM: Protein of unknown function (DUF2804); hypothetical protein 600959 10578969 Trebr_0485 Treponema brennaborense DSM 12168 hypothetical protein YP_004439060.1 599892 R 906968 CDS YP_004439061.1 332297139 10578970 601096..602637 1 NC_015500.1 COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: tde:TDE1444 metallo-beta-lactamase family protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504919358; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain; RNA-metabolising metallo-beta-lactamase 602637 10578970 Trebr_0486 Treponema brennaborense DSM 12168 RNA-metabolising metallo-beta-lactamase YP_004439061.1 601096 D 906968 CDS YP_004439062.1 332297140 10578971 complement(602687..604075) 1 NC_015500.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: tpp:TPASS_0108 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: Phosphofructokinase; PRIAM: 6-phosphofructokinase; SPTR: Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (Pfk); IMG reference gene:2504919359; PFAM: Phosphofructokinase; 6-phosphofructokinase 604075 10578971 Trebr_0487 Treponema brennaborense DSM 12168 6-phosphofructokinase YP_004439062.1 602687 R 906968 CDS YP_004439063.1 332297141 10578978 605356..605967 1 NC_015500.1 KEGG: pin:Ping_2866 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919366; hypothetical protein 605967 10578978 Trebr_0488 Treponema brennaborense DSM 12168 hypothetical protein YP_004439063.1 605356 D 906968 CDS YP_004439064.1 332297142 10578979 complement(606019..607533) 1 NC_015500.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680; KEGG: dbr:Deba_2655 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase; IMG reference gene:2504919367; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type; amidohydrolase 607533 10578979 Trebr_0489 Treponema brennaborense DSM 12168 amidohydrolase YP_004439064.1 606019 R 906968 CDS YP_004439065.1 332297143 10578980 complement(607533..607973) 1 NC_015500.1 COGs: COG1781 Aspartate carbamoyltransferase regulatory subunit; InterPro IPR020545; KEGG: cbf:CLI_3379 aspartate carbamoyltransferase regulatory subunit; PFAM: Aspartate carbamoyltransferase regulatory subunit, N-terminal; SPTR: Aspartate carbamoyltransferase regulatory chain; IMG reference gene:2504919368; PFAM: Aspartate carbamoyltransferase regulatory chain, metal binding domain; Aspartate carbamoyltransferase regulatory chain, allosteric domain; TIGRFAM: aspartate carbamoyltransferase, regulatory subunit; aspartate carbamoyltransferase regulatory subunit 607973 10578980 Trebr_0490 Treponema brennaborense DSM 12168 aspartate carbamoyltransferase regulatory subunit YP_004439065.1 607533 R 906968 CDS YP_004439066.1 332297144 10578981 complement(607973..608896) 1 NC_015500.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: cbt:CLH_2347 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504919369; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; aspartate carbamoyltransferase 608896 10578981 Trebr_0491 Treponema brennaborense DSM 12168 aspartate carbamoyltransferase YP_004439066.1 607973 R 906968 CDS YP_004439067.1 332297145 10578983 611499..611975 1 NC_015500.1 KEGG: bcl:ABC0535 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919371; hypothetical protein 611975 10578983 Trebr_0493 Treponema brennaborense DSM 12168 hypothetical protein YP_004439067.1 611499 D 906968 CDS YP_004439068.1 332297146 10578984 612273..613643 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: csh:Closa_1533 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919372; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 613643 10578984 Trebr_0494 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004439068.1 612273 D 906968 CDS YP_004439069.1 332297147 10578985 613624..614553 1 NC_015500.1 KEGG: bpo:BP951000_1114 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919373; hypothetical protein 614553 10578985 Trebr_0495 Treponema brennaborense DSM 12168 hypothetical protein YP_004439069.1 613624 D 906968 CDS YP_004439070.1 332297148 10578986 complement(614646..617042) 1 NC_015500.1 COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342:IPR010383:IPR010403; KEGG: cpy:Cphy_3854 glycosyltransferase 36; PFAM: Glycosyltransferase 36; carbohydrate binding; Glycosyltransferase 36 associated; SPTR: Glycosyltransferase 36; IMG reference gene:2504919374; PFAM: Glycosyltransferase family 36; carbohydrate binding domain; Protein of unknown function, DUF608; Glycosyltransferase 36 associated family; glycosyltransferase 617042 10578986 Trebr_0496 Treponema brennaborense DSM 12168 glycosyltransferase YP_004439070.1 614646 R 906968 CDS YP_004439071.1 332297149 10578987 complement(617272..617781) 1 NC_015500.1 KEGG: tde:TDE0118 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919375; PFAM: FlgN protein; hypothetical protein 617781 10578987 Trebr_0497 Treponema brennaborense DSM 12168 hypothetical protein YP_004439071.1 617272 R 906968 CDS YP_004439072.1 332297150 10578988 complement(617786..618226) 1 NC_015500.1 COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: tde:TDE0119 flagellar protein FliS; PFAM: Flagellar protein FliS; SPTR: Flagellar protein FliS; TIGRFAM: Flagellar protein FliS; IMG reference gene:2504919376; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS; flagellar protein FliS 618226 10578988 Trebr_0498 Treponema brennaborense DSM 12168 flagellar protein FliS YP_004439072.1 617786 R 906968 CDS YP_004439073.1 332297151 10578989 618362..620344 1 NC_015500.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593:IPR011546:IPR003959:IPR000642:IPR 005936; KEGG: tde:TDE0470 cell division protein FtsH; PFAM: ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; Peptidase M41; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protease FtsH homolog; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504919377; PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; ATP-dependent metalloprotease FtsH 620344 10578989 Trebr_0499 Treponema brennaborense DSM 12168 ATP-dependent metalloprotease FtsH YP_004439073.1 618362 D 906968 CDS YP_004439074.1 332297152 10578990 620522..621910 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cpy:Cphy_3019 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919378; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 621910 10578990 Trebr_0500 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004439074.1 620522 D 906968 CDS YP_004439075.1 332297153 10578991 complement(622013..622282) 1 NC_015500.1 COGs: COG3830 ACT domain-containing protein; HAMAP: UPF0237 protein; InterPro IPR002912; KEGG: hor:Hore_14440 hypothetical protein; PFAM: Amino acid-binding ACT; SPTR: UPF0237 protein POTG_03406; IMG reference gene:2504919379; PFAM: ACT domain; ACT domain-containing protein 622282 10578991 Trebr_0501 Treponema brennaborense DSM 12168 ACT domain-containing protein YP_004439075.1 622013 R 906968 CDS YP_004439076.1 332297154 10578992 complement(622476..623714) 1 NC_015500.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674; KEGG: clj:CLJU_c04120 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2504919380; PFAM: HD domain; metal-dependent phosphohydrolase HD sub domain-containing protein 623714 10578992 Trebr_0502 Treponema brennaborense DSM 12168 metal-dependent phosphohydrolase HD sub domain-containing protein YP_004439076.1 622476 R 906968 CDS YP_004439077.1 332297155 10578993 623769..626384 1 NC_015500.1 KEGG: ssm:Spirs_2256 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919381; hypothetical protein 626384 10578993 Trebr_0503 Treponema brennaborense DSM 12168 hypothetical protein YP_004439077.1 623769 D 906968 CDS YP_004439078.1 332297156 10578994 complement(626485..627423) 1 NC_015500.1 COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: csh:Closa_2921 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; IMG reference gene:2504919382; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; cysteine synthase A 627423 10578994 Trebr_0504 Treponema brennaborense DSM 12168 cysteine synthase A YP_004439078.1 626485 R 906968 CDS YP_004439079.1 332297157 10578995 627769..629808 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004010:IPR003660; KEGG: geo:Geob_2266 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504919383; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 629808 10578995 Trebr_0505 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer with Cache sensor YP_004439079.1 627769 D 906968 CDS YP_004439080.1 332297158 10578996 629783..630508 1 NC_015500.1 KEGG: coc:Coch_1988 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919384; PFAM: DNA alkylation repair enzyme; hypothetical protein 630508 10578996 Trebr_0506 Treponema brennaborense DSM 12168 hypothetical protein YP_004439080.1 629783 D 906968 CDS YP_004439081.1 332297159 10578997 630574..630906 1 NC_015500.1 COGs: COG2127 conserved hypothetical protein; HAMAP: ATP-dependent Clp protease adapter protein clpS; InterPro IPR003769; KEGG: sta:STHERM_c12620 ATP-dependent Clp protease adaptor protein ClpS; PFAM: Adaptor protein ClpS, core; SPTR: ATP-dependent Clp protease adaptor protein clpS; IMG reference gene:2504919385; PFAM: ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adapter protein clpS 630906 10578997 Trebr_0507 Treponema brennaborense DSM 12168 ATP-dependent Clp protease adapter protein clpS YP_004439081.1 630574 D 906968 CDS YP_004439082.1 332297160 10578998 630903..633494 1 NC_015500.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR013093:IPR 019489:IPR013461; KEGG: tde:TDE2124 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; IMG reference gene:2504919386; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; ATP-dependent Clp protease ATP-binding protein ClpA 633494 10578998 Trebr_0508 Treponema brennaborense DSM 12168 ATP-dependent Clp protease ATP-binding protein ClpA YP_004439082.1 630903 D 906968 CDS YP_004439083.1 332297161 10578999 633487..634203 1 NC_015500.1 COGs: COG2360 Leu/Phe-tRNA-protein transferase; HAMAP: Leucyl/phenylalanyl-tRNA-protein transferase; InterPro IPR004616; KEGG: ank:AnaeK_0840 leucyl/phenylalanyl-tRNA--protein transferase; PFAM: Leucyl/phenylalanyl-tRNA-protein transferase; PRIAM: Leucyltransferase; SPTR: Leucyl/phenylalanyl-tRNA--protein transferase; TIGRFAM: Leucyl/phenylalanyl-tRNA-protein transferase; IMG reference gene:2504919387; PFAM: Leucyl/phenylalanyl-tRNA protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA--protein transferase; leucyl/phenylalanyl-tRNA--protein transferase 634203 10578999 Trebr_0509 Treponema brennaborense DSM 12168 leucyl/phenylalanyl-tRNA--protein transferase YP_004439083.1 633487 D 906968 CDS YP_004439084.1 332297162 10579000 complement(634309..635454) 1 NC_015500.1 COGs: COG3392 Adenine-specific DNA methylase; InterPro IPR012327; KEGG: cco:CCC13826_1858 D12 class N6 adenine-specific DNA methyltransferase superfamily protein; PFAM: D12 class N6 adenine-specific DNA methyltransferase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: D12 class N6 adenine-specific DNA methyltransferase; IMG reference gene:2504919388; PFAM: D12 class N6 adenine-specific DNA methyltransferase; adenine-specific DNA-methyltransferase 635454 10579000 Trebr_0510 Treponema brennaborense DSM 12168 adenine-specific DNA-methyltransferase YP_004439084.1 634309 R 906968 CDS YP_004439085.1 332297163 10579001 complement(635451..636158) 1 NC_015500.1 COGs: COG1346 effector of murein hydrolase; InterPro IPR007300; KEGG: cno:NT01CX_0755 LrgB family protein; PFAM: LrgB-like protein; SPTR: uncharacterized protein; IMG reference gene:2504919389; PFAM: LrgB-like family; LrgB family protein 636158 10579001 Trebr_0511 Treponema brennaborense DSM 12168 LrgB family protein YP_004439085.1 635451 R 906968 CDS YP_004439086.1 332297164 10579002 complement(636155..636547) 1 NC_015500.1 COGs: COG1380 effector of murein hydrolase LrgA; InterPro IPR005538; KEGG: ctc:CTC01825 murein hydrolase exporter; PFAM: LrgA; SPTR: uncharacterized protein; IMG reference gene:2504919390; PFAM: LrgA family; LrgA family protein 636547 10579002 Trebr_0512 Treponema brennaborense DSM 12168 LrgA family protein YP_004439086.1 636155 R 906968 CDS YP_004439087.1 332297165 10579003 636729..638075 1 NC_015500.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: amu:Amuc_2051 glutamate dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP(+)); IMG reference gene:2504919391; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate dehydrogenase (NADP(+)) 638075 10579003 Trebr_0513 Treponema brennaborense DSM 12168 Glutamate dehydrogenase (NADP(+)) YP_004439087.1 636729 D 906968 CDS YP_004439088.1 332297166 10579004 638272..639285 1 NC_015500.1 InterPro IPR004089:IPR004010; KEGG: hmo:HM1_1061 methyl-accepting chemotaxis protein; PFAM: Cache; Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919392; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; Cache domain-containing protein 639285 10579004 Trebr_0514 Treponema brennaborense DSM 12168 Cache domain-containing protein YP_004439088.1 638272 D 906968 CDS YP_004439089.1 332297167 10579005 639343..640608 1 NC_015500.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277:IPR006235; KEGG: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; IMG reference gene:2504919393; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; O-acetylhomoserine/O-acetylserine sulfhydrylase 640608 10579005 Trebr_0515 Treponema brennaborense DSM 12168 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_004439089.1 639343 D 906968 CDS YP_004439090.1 332297168 10579006 640618..641403 1 NC_015500.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; KEGG: tde:TDE0796 histidinol phosphate phosphatase HisJ family protein; SPTR: Histidinol phosphate phosphatase HisJ family protein; IMG reference gene:2504919394; TIGRFAM: histidinol phosphate phosphatase HisJ family; histidinol phosphate phosphatase HisJ family protein 641403 10579006 Trebr_0516 Treponema brennaborense DSM 12168 histidinol phosphate phosphatase HisJ family protein YP_004439090.1 640618 D 906968 CDS YP_004439091.1 332297169 10579007 complement(641447..641809) 1 NC_015500.1 InterPro IPR012427; KEGG: bth:BT_0170 hypothetical protein; PFAM: Protein of unknown function DUF1622; SPTR: uncharacterized protein; IMG reference gene:2504919395; PFAM: Protein of unknown function (DUF1622); hypothetical protein 641809 10579007 Trebr_0517 Treponema brennaborense DSM 12168 hypothetical protein YP_004439091.1 641447 R 906968 CDS YP_004439092.1 332297170 10579008 complement(641829..642236) 1 NC_015500.1 COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: tde:TDE2225 thioesterase family protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family protein; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; IMG reference gene:2504919396; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family; 4-hydroxybenzoyl-CoA thioesterase 642236 10579008 Trebr_0518 Treponema brennaborense DSM 12168 4-hydroxybenzoyl-CoA thioesterase YP_004439092.1 641829 R 906968 CDS YP_004439093.1 332297171 10579009 complement(642375..645107) 1 NC_015500.1 KEGG: tde:TDE2611 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919397; hypothetical protein 645107 10579009 Trebr_0519 Treponema brennaborense DSM 12168 hypothetical protein YP_004439093.1 642375 R 906968 CDS YP_004439094.1 332297172 10579010 645226..646494 1 NC_015500.1 COGs: COG2262 GTPase; InterPro IPR002917:IPR016496:IPR005225; KEGG: ssm:Spirs_3087 GTP-binding protein HflX; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding proten HflX; TIGRFAM: GTP-binding protein, HflX; Small GTP-binding protein; IMG reference gene:2504919398; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain; GTP-binding proten HflX 646494 10579010 Trebr_0520 Treponema brennaborense DSM 12168 GTP-binding proten HflX YP_004439094.1 645226 D 906968 CDS YP_004439095.1 332297173 10579011 646522..646995 1 NC_015500.1 InterPro IPR005503; KEGG: tde:TDE2322 flagellar protein FliL-related protein; PFAM: Flagellar basal body-associated protein FliL; SPTR: Orf protein; IMG reference gene:2504919399; PFAM: Flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 646995 10579011 Trebr_0521 Treponema brennaborense DSM 12168 flagellar basal body-associated protein FliL YP_004439095.1 646522 D 906968 CDS YP_004439096.1 332297174 10579012 647142..647498 1 NC_015500.1 KEGG: tde:TDE2321 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919400; hypothetical protein 647498 10579012 Trebr_0522 Treponema brennaborense DSM 12168 hypothetical protein YP_004439096.1 647142 D 906968 CDS YP_004439097.1 332297175 10579013 647485..648060 1 NC_015500.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: tde:TDE2320 RNA polymerase sigma-24 factor, PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2; SPTR: RNA polymerase sigma-24 factor, ; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504919401; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 648060 10579013 Trebr_0523 Treponema brennaborense DSM 12168 ECF subfamily RNA polymerase sigma-24 subunit YP_004439097.1 647485 D 906968 CDS YP_004439098.1 332297176 10579014 648072..648539 1 NC_015500.1 KEGG: tde:TDE2319 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919402; hypothetical protein 648539 10579014 Trebr_0524 Treponema brennaborense DSM 12168 hypothetical protein YP_004439098.1 648072 D 906968 CDS YP_004439099.1 332297177 10579015 complement(648598..650895) 1 NC_015500.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: tde:TDE2335 ATP-dependent DNA helicase UvrD; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase PcrA; IMG reference gene:2504919403; PFAM: UvrD/REP helicase; UvrD/REP helicase 650895 10579015 Trebr_0525 Treponema brennaborense DSM 12168 UvrD/REP helicase YP_004439099.1 648598 R 906968 CDS YP_004439100.1 332297178 10579016 complement(650910..652436) 1 NC_015500.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: Ribosomal protein S12 methylthiotransferase RimO; InterProIPR005840:IPR006638:IPR013848:IPR007197:IPR 005839; KEGG: tde:TDE2609 tRNA modifying protein; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: Ribosomal protein S12 methylthiotransferase RimO; Methylthiotransferase; IMG reference gene:2504919404; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family; Ribosomal protein S12 methylthiotransferase rimO 652436 10579016 Trebr_0526 Treponema brennaborense DSM 12168 Ribosomal protein S12 methylthiotransferase rimO YP_004439100.1 650910 R 906968 CDS YP_004439101.1 332297179 10579017 complement(652429..653514) 1 NC_015500.1 COGs: COG1426 conserved hypothetical protein; KEGG: tde:TDE2608 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919405; hypothetical protein 653514 10579017 Trebr_0527 Treponema brennaborense DSM 12168 hypothetical protein YP_004439101.1 652429 R 906968 CDS YP_004439102.1 332297180 10579018 complement(653531..654205) 1 NC_015500.1 COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: tpp:TPASS_0333 hypothetical protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA; IMG reference gene:2504919406; PFAM: Outer membrane lipoprotein carrier protein LolA; outer membrane lipoprotein carrier protein LolA 654205 10579018 Trebr_0528 Treponema brennaborense DSM 12168 outer membrane lipoprotein carrier protein LolA YP_004439102.1 653531 R 906968 CDS YP_004439103.1 332297181 10579019 complement(654403..656136) 1 NC_015500.1 COGs: COG1001 Adenine deaminase; HAMAP: Adenine deaminase; InterPro IPR006680:IPR006679; KEGG: dps:DP1374 adenine deaminase; PFAM: Amidohydrolase 1; PRIAM: Adenine deaminase; SPTR: Adenine deaminase 1; TIGRFAM: Adenine deaminase; IMG reference gene:2504919407; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; adenine deaminase 656136 10579019 Trebr_0529 Treponema brennaborense DSM 12168 adenine deaminase YP_004439103.1 654403 R 906968 CDS YP_004439104.1 332297182 10579020 complement(656133..657344) 1 NC_015500.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: ssm:Spirs_2663 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504919408; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 657344 10579020 Trebr_0530 Treponema brennaborense DSM 12168 signal transduction histidine kinase YP_004439104.1 656133 R 906968 CDS YP_004439105.1 332297183 10579021 657412..657885 1 NC_015500.1 IMG reference gene:2504919409; hypothetical protein 657885 10579021 Trebr_0531 Treponema brennaborense DSM 12168 hypothetical protein YP_004439105.1 657412 D 906968 CDS YP_004439106.1 332297184 10579022 complement(657880..658575) 1 NC_015500.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: mpt:Mpe_A1026 response regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver region; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver region; SPTR: Response regulator protein; IMG reference gene:2504919410; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; two component transcriptional regulator, LuxR family 658575 10579022 Trebr_0532 Treponema brennaborense DSM 12168 two component transcriptional regulator, LuxR family YP_004439106.1 657880 R 906968 CDS YP_004439107.1 332297185 10579023 658727..659683 1 NC_015500.1 InterPro IPR005532; KEGG: cpy:Cphy_2106 hypothetical protein; PFAM: Sulphatase-modifying factor; SPTR: uncharacterized protein; IMG reference gene:2504919411; PFAM: Formylglycine-generating sulfatase enzyme; sulfatase-modifying factor protein 659683 10579023 Trebr_0533 Treponema brennaborense DSM 12168 sulfatase-modifying factor protein YP_004439107.1 658727 D 906968 CDS YP_004439108.1 332297186 10579024 659776..660780 1 NC_015500.1 InterPro IPR005532; KEGG: tde:TDE2145 hypothetical protein; PFAM: Sulphatase-modifying factor; SPTR: uncharacterized protein; IMG reference gene:2504919412; PFAM: Formylglycine-generating sulfatase enzyme; sulfatase-modifying factor protein 660780 10579024 Trebr_0534 Treponema brennaborense DSM 12168 sulfatase-modifying factor protein YP_004439108.1 659776 D 906968 CDS YP_004439109.1 332297187 10579025 660991..662289 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR010822; KEGG: dal:Dalk_1277 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-related; SPTR: Protein serine/threonine phosphatase; IMG reference gene:2504919413; PFAM: Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 662289 10579025 Trebr_0535 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase YP_004439109.1 660991 D 906968 CDS YP_004439110.1 332297188 10579026 662478..662720 1 NC_015500.1 IMG reference gene:2504919414; hypothetical protein 662720 10579026 Trebr_0536 Treponema brennaborense DSM 12168 hypothetical protein YP_004439110.1 662478 D 906968 CDS YP_004439111.1 332297189 10579027 complement(662695..663858) 1 NC_015500.1 COGs: COG4214 ABC-type xylose transport system permease component; InterPro IPR001851; KEGG: cst:CLOST_0544 D-xylose transporter subunit ; membrane component of ABC superfamily; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504919415; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 663858 10579027 Trebr_0537 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439111.1 662695 R 906968 CDS YP_004439112.1 332297190 10579028 complement(663897..665417) 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cag:Cagg_2577 ABC transporter-like protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504919416; PFAM: ABC transporter; monosaccharide-transporting ATPase 665417 10579028 Trebr_0538 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439112.1 663897 R 906968 CDS YP_004439113.1 332297191 10579029 complement(665497..666597) 1 NC_015500.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: cst:CLOST_0542 ribose ABC transporter (ribose-binding protein); SPTR: Periplasmic sugar-binding protein; IMG reference gene:2504919417; PFAM: family; ribose ABC transporter substrate-binding protein 666597 10579029 Trebr_0539 Treponema brennaborense DSM 12168 ribose ABC transporter substrate-binding protein YP_004439113.1 665497 R 906968 CDS YP_004439114.1 332297192 10579030 complement(666850..667923) 1 NC_015500.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: pjd:Pjdr2_0976 D-xylose ABC transporter, periplasmic substrate-binding protein; SPTR: Periplasmic binding protein/LacI transcriptional regulator; IMG reference gene:2504919418; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein; D-xylose ABC transporter periplasmic substrate-binding protein 667923 10579030 Trebr_0540 Treponema brennaborense DSM 12168 D-xylose ABC transporter periplasmic substrate-binding protein YP_004439114.1 666850 R 906968 CDS YP_004439115.1 332297193 10579031 complement(668127..669695) 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: cpy:Cphy_1583 two component AraC family transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region; SPTR: Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; IMG reference gene:2504919419; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 669695 10579031 Trebr_0541 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439115.1 668127 R 906968 CDS YP_004439116.1 332297194 10579032 complement(669688..671166) 1 NC_015500.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660:IPR010559:IPR003594; KEGG: bpb:bpr_I1170 two component system histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; SPTR: Two component system histidine kinase; IMG reference gene:2504919420; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 671166 10579032 Trebr_0542 Treponema brennaborense DSM 12168 signal transduction histidine kinase YP_004439116.1 669688 R 906968 CDS YP_004439117.1 332297195 10579033 complement(671163..672149) 1 NC_015500.1 KEGG: bpb:bpr_I1169 sugar ABC transporter substrate-binding protein; SPTR: Sugar ABC transporter substrate-binding protein; IMG reference gene:2504919421; hypothetical protein 672149 10579033 Trebr_0543 Treponema brennaborense DSM 12168 hypothetical protein YP_004439117.1 671163 R 906968 CDS YP_004439118.1 332297196 10579034 672351..673208 1 NC_015500.1 COGs: COG3708 conserved hypothetical protein; InterPro IPR018060:IPR000005:IPR010499; KEGG: cdf:CD1883 AraC family transcription regulator; PFAM: Bacterial transcription activator, effector binding; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504919422; PFAM: Bacterial transcription activator, effector binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 673208 10579034 Trebr_0544 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439118.1 672351 D 906968 CDS YP_004439119.1 332297197 10579035 complement(673360..674199) 1 NC_015500.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: cpf:CPF_1834 cobalt ABC transporter, permease protein; PFAM: Cobalt transport protein; SPTR: uncharacterized protein; IMG reference gene:2504919423; PFAM: Cobalt transport protein; ABC transporter permease 674199 10579035 Trebr_0545 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439119.1 673360 R 906968 CDS YP_004439120.1 332297198 10579036 complement(674189..675901) 1 NC_015500.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003593:IPR003439; KEGG: bpb:bpr_I2067 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ATPase components of various ABC-type transport systems, contain duplicated ATPase; IMG reference gene:2504919424; PFAM: ABC transporter; ATP-binding cassette cobalt transporter; monosaccharide-transporting ATPase 675901 10579036 Trebr_0546 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439120.1 674189 R 906968 CDS YP_004439121.1 332297199 10579037 complement(675934..676482) 1 NC_015500.1 COGs: COG4720 membrane protein; HAMAP: UPF0397 protein; InterPro IPR009825; KEGG: bpb:bpr_I2068 hypothetical protein; PFAM: Protein of unknown function DUF1393; SPTR: UPF0397 protein RUMOBE_00298; IMG reference gene:2504919425; PFAM: Protein of unknown function (DUF1393); hypothetical protein 676482 10579037 Trebr_0547 Treponema brennaborense DSM 12168 hypothetical protein YP_004439121.1 675934 R 906968 CDS YP_004439122.1 332297200 10579038 complement(676530..677384) 1 NC_015500.1 COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: bpu:BPUM_3680 hypothetical protein; PFAM: Protein of unknown function DUF62; SPTR: Molybdate/tungstate binding protein; IMG reference gene:2504919426; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase; hypothetical protein 677384 10579038 Trebr_0548 Treponema brennaborense DSM 12168 hypothetical protein YP_004439122.1 676530 R 906968 CDS YP_004439123.1 332297201 10579039 677585..679294 1 NC_015500.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: Bifunctional purine biosynthesis protein purH; InterPro IPR013982:IPR011607; KEGG: bhy:BHWA1_02509 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, formylation region; MGS-like; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, formylation region; SPTR: Bifunctional purine biosynthesis protein purH; IMG reference gene:2504919427; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 679294 10579039 Trebr_0549 Treponema brennaborense DSM 12168 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004439123.1 677585 D 906968 CDS YP_004439124.1 332297202 10579040 679306..680376 1 NC_015500.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: tde:TDE2249 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4, conserved region; PRIAM:Phospho-N-acetylmuramoyl-pentapeptide-transfe rase; SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; IMG reference gene:2504919428; PFAM: Glycosyl transferase family 4; Phospho-N-acetylmuramoyl-pentapeptide- transferase 680376 10579040 Trebr_0550 Treponema brennaborense DSM 12168 Phospho-N-acetylmuramoyl-pentapeptide- transferase YP_004439124.1 679306 D 906968 CDS YP_004439125.1 332297203 10579041 680463..681767 1 NC_015500.1 KEGG: tde:TDE1404 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504919429; lipoprotein 681767 10579041 Trebr_0551 Treponema brennaborense DSM 12168 lipoprotein YP_004439125.1 680463 D 906968 CDS YP_004439126.1 332297204 10579042 681776..683824 1 NC_015500.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: tde:TDE1403 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504919430; PFAM: ABC transporter; ABC transporter 683824 10579042 Trebr_0552 Treponema brennaborense DSM 12168 ABC transporter YP_004439126.1 681776 D 906968 CDS YP_004439127.1 332297205 10579043 complement(683931..685838) 1 NC_015500.1 InterPro IPR005077; KEGG: cth:Cthe_0249 peptidase C11, clostripain; PFAM: Peptidase C11, clostripain; SPTR: Peptidase C11 clostripain; IMG reference gene:2504919431; PFAM: Clostripain family; peptidase C11 clostripain 685838 10579043 Trebr_0553 Treponema brennaborense DSM 12168 peptidase C11 clostripain YP_004439127.1 683931 R 906968 CDS YP_004439128.1 332297206 10579044 686049..687029 1 NC_015500.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: cte:CT0024 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; IMG reference gene:2504919432; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; UDP-glucose 4-epimerase 687029 10579044 Trebr_0554 Treponema brennaborense DSM 12168 UDP-glucose 4-epimerase YP_004439128.1 686049 D 906968 CDS YP_004439129.1 332297207 10579045 687029..688258 1 NC_015500.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR010182; KEGG: tde:TDE0068 diaminopimelate aminotransferase; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Succinyl-diaminopimelate desuccinylase; TIGRFAM: Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase; IMG reference gene:2504919433; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase 688258 10579045 Trebr_0555 Treponema brennaborense DSM 12168 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase YP_004439129.1 687029 D 906968 CDS YP_004439130.1 332297208 10579046 688328..688945 1 NC_015500.1 KEGG: emi:Emin_0189 hypothetical protein; SPTR: Uncharacterized proteobacterial lipoprotein; IMG reference gene:2504919434; TIGRFAM: uncharacterized proteobacterial lipoprotein; hypothetical protein 688945 10579046 Trebr_0556 Treponema brennaborense DSM 12168 hypothetical protein YP_004439130.1 688328 D 906968 CDS YP_004439131.1 332297209 10579047 688945..690279 1 NC_015500.1 COGs: COG3014 conserved hypothetical protein; KEGG: cts:Ctha_1249 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919435; hypothetical protein 690279 10579047 Trebr_0557 Treponema brennaborense DSM 12168 hypothetical protein YP_004439131.1 688945 D 906968 CDS YP_004439132.1 332297210 10579048 690267..691301 1 NC_015500.1 KEGG: nde:NIDE1649 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919436; hypothetical protein 691301 10579048 Trebr_0558 Treponema brennaborense DSM 12168 hypothetical protein YP_004439132.1 690267 D 906968 CDS YP_004439133.1 332297211 10579049 691321..693561 1 NC_015500.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: tde:TDE0071 U32 family peptidase; PFAM: Peptidase U32; SPTR: Peptidase, U32 family; IMG reference gene:2504919437; PFAM: Peptidase family U32; peptidase U32 693561 10579049 Trebr_0559 Treponema brennaborense DSM 12168 peptidase U32 YP_004439133.1 691321 D 906968 CDS YP_004439134.1 332297212 10579050 complement(693741..694208) 1 NC_015500.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: ssm:Spirs_3718 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504919438; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein 694208 10579050 Trebr_0560 Treponema brennaborense DSM 12168 single-strand binding protein YP_004439134.1 693741 R 906968 CDS YP_004439135.1 332297213 10579051 complement(694306..696234) 1 NC_015500.1 KEGG: tde:TDE0585 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919439; hypothetical protein 696234 10579051 Trebr_0561 Treponema brennaborense DSM 12168 hypothetical protein YP_004439135.1 694306 R 906968 CDS YP_004439136.1 332297214 10579052 696387..697268 1 NC_015500.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: elm:ELI_2771 NAD-dependent protein deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent protein deacetylases, SIR2 family; IMG reference gene:2504919440; PFAM: Sir2 family; NAD-dependent deacetylase 697268 10579052 Trebr_0562 Treponema brennaborense DSM 12168 NAD-dependent deacetylase YP_004439136.1 696387 D 906968 CDS YP_004439137.1 332297215 10579053 complement(697287..698939) 1 NC_015500.1 COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR010766:IPR001667; KEGG: gur:Gura_4157 manganese-dependent inorganic pyrophosphatase; PFAM: Cystathionine beta-synthase, core; DRTGG; Phosphoesterase, RecJ-like; PRIAM: Inorganic diphosphatase; SPTR: Inorganic diphosphatase; IMG reference gene:2504919441; PFAM: DRTGG domain; DHH family; CBS domain; DHHA2 domain; inorganic diphosphatase 698939 10579053 Trebr_0563 Treponema brennaborense DSM 12168 inorganic diphosphatase YP_004439137.1 697287 R 906968 CDS YP_004439138.1 332297216 10579054 complement(699028..699432) 1 NC_015500.1 COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; InterPro IPR005175; KEGG: ipo:Ilyop_0746 protein of unknown function DUF296; PFAM: Protein of unknown function DUF296; SPTR: uncharacterized protein; manually curated; IMG reference gene:2504919442; PFAM: Domain of unknown function (DUF296); hypothetical protein 699432 10579054 Trebr_0564 Treponema brennaborense DSM 12168 hypothetical protein YP_004439138.1 699028 R 906968 CDS YP_004439139.1 332297217 10579055 699743..701305 1 NC_015500.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: ssm:Spirs_4115 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; TIGRFAM: Glycoside hydrolase, family 77; IMG reference gene:2504919443; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 701305 10579055 Trebr_0565 Treponema brennaborense DSM 12168 4-alpha-glucanotransferase YP_004439139.1 699743 D 906968 CDS YP_004439140.1 332297218 10579056 701317..702051 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: sli:Slin_2869 pseudouridine synthase, RluA family; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; IMG reference gene:2504919444; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; pseudouridine synthase 702051 10579056 Trebr_0566 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004439140.1 701317 D 906968 CDS YP_004439141.1 332297219 10579057 702260..703558 1 NC_015500.1 COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834:IPR000866; KEGG: ele:Elen_0625 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane region; Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; IMG reference gene:2504919445; PFAM: AhpC/TSA family; Cytochrome C biogenesis protein transmembrane region; cytochrome c biogenesis protein transmembrane region 703558 10579057 Trebr_0567 Treponema brennaborense DSM 12168 cytochrome c biogenesis protein transmembrane region YP_004439141.1 702260 D 906968 CDS YP_004439142.1 332297220 10579058 complement(703648..704406) 1 NC_015500.1 KEGG: ssm:Spirs_2341 hypothetical protein; SPTR: membrane protein; IMG reference gene:2504919446; hypothetical protein 704406 10579058 Trebr_0568 Treponema brennaborense DSM 12168 hypothetical protein YP_004439142.1 703648 R 906968 CDS YP_004439143.1 332297221 10579059 704497..704952 1 NC_015500.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: gem:GM21_0359 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504919447; PFAM: MarR family; MarR family transcriptional regulator 704952 10579059 Trebr_0569 Treponema brennaborense DSM 12168 MarR family transcriptional regulator YP_004439143.1 704497 D 906968 CDS YP_004439144.1 332297222 10579060 705074..706150 1 NC_015500.1 COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: tde:TDE0951 lipoprotein; PFAM: Basic membrane lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504919448; PFAM: Basic membrane protein; basic membrane lipoprotein 706150 10579060 Trebr_0570 Treponema brennaborense DSM 12168 basic membrane lipoprotein YP_004439144.1 705074 D 906968 CDS YP_004439145.1 332297223 10579061 706184..707737 1 NC_015500.1 COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: kra:Krad_2122 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504919449; PFAM: ABC transporter; monosaccharide-transporting ATPase 707737 10579061 Trebr_0571 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439145.1 706184 D 906968 CDS YP_004439146.1 332297224 10579062 707734..708795 1 NC_015500.1 COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: tde:TDE0953 branched-chain amino acid ABC transporter, permease protein; PFAM: Bacterial inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter, permease protein; IMG reference gene:2504919450; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 708795 10579062 Trebr_0572 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439146.1 707734 D 906968 CDS YP_004439147.1 332297225 10579063 708797..709624 1 NC_015500.1 COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: tde:TDE0954 branched-chain amino acid ABC transporter, permease protein; PFAM: Bacterial inner-membrane translocator; SPTR: Branched-chain amino acid ABC transporter, permease protein; IMG reference gene:2504919451; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 709624 10579063 Trebr_0573 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439147.1 708797 D 906968 CDS YP_004439148.1 332297226 10579064 complement(709628..710488) 1 NC_015500.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: cdf:CD0672 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: uncharacterized protein; IMG reference gene:2504919452; PFAM: NIF3 (NGG1p interacting factor 3); NGG1p interacting factor 3 protein, NIF3 710488 10579064 Trebr_0574 Treponema brennaborense DSM 12168 NGG1p interacting factor 3 protein, NIF3 YP_004439148.1 709628 R 906968 CDS YP_004439149.1 332297227 10579065 complement(710573..712603) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: sta:STHERM_c11590 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: uncharacterized protein; IMG reference gene:2504919453; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 712603 10579065 Trebr_0575 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439149.1 710573 R 906968 CDS YP_004439150.1 332297228 10579066 complement(713124..714728) 1 NC_015500.1 COGs: COG1384 Lysyl-tRNA synthetase (class I); HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; InterPro IPR020756:IPR020754:IPR002904; KEGG: tde:TDE2553 lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class Ic; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class I; IMG reference gene:2504919454; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Lysyl-tRNA synthetase 714728 10579066 Trebr_0576 Treponema brennaborense DSM 12168 Lysyl-tRNA synthetase YP_004439150.1 713124 R 906968 CDS YP_004439151.1 332297229 10579067 715089..716987 1 NC_015500.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: tde:TDE2109 DEAD-box ATP dependent DNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase; IMG reference gene:2504919455; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase domain protein 716987 10579067 Trebr_0577 Treponema brennaborense DSM 12168 DEAD/DEAH box helicase domain protein YP_004439151.1 715089 D 906968 CDS YP_004439152.1 332297230 10579068 complement(716988..717899) 1 NC_015500.1 KEGG: ssm:Spirs_0543 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919456; hypothetical protein 717899 10579068 Trebr_0578 Treponema brennaborense DSM 12168 hypothetical protein YP_004439152.1 716988 R 906968 CDS YP_004439153.1 332297231 10579069 complement(717947..719461) 1 NC_015500.1 COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tde:TDE1579 fibronectin/fibrinogen-binding protein, internal deletion; PFAM: Fibronectin-binding A, N-terminal; Protein of unknown function DUF814; SPTR: uncharacterized protein; IMG reference gene:2504919457; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); fibronectin-binding A domain-containing protein 719461 10579069 Trebr_0579 Treponema brennaborense DSM 12168 fibronectin-binding A domain-containing protein YP_004439153.1 717947 R 906968 CDS YP_004439154.1 332297232 10579070 complement(719699..720364) 1 NC_015500.1 KEGG: tpp:TPASS_0989 protein P26; SPTR: uncharacterized protein; IMG reference gene:2504919458; protein P26 720364 10579070 Trebr_0580 Treponema brennaborense DSM 12168 protein P26 YP_004439154.1 719699 R 906968 CDS YP_004439155.1 332297233 10579071 720425..723814 1 NC_015500.1 InterPro IPR019734:IPR001440; KEGG: tde:TDE1092 hypothetical protein; PFAM: Tetratricopeptide TPR-1; SPTR: uncharacterized protein; IMG reference gene:2504919459; hypothetical protein 723814 10579071 Trebr_0581 Treponema brennaborense DSM 12168 hypothetical protein YP_004439155.1 720425 D 906968 CDS YP_004439156.1 332297234 10579072 723879..724505 1 NC_015500.1 COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: tde:TDE2717 phosphatidate cytidylyltransferase, PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase, ; IMG reference gene:2504919460; PFAM: Cytidylyltransferase family; phosphatidate cytidylyltransferase 724505 10579072 Trebr_0582 Treponema brennaborense DSM 12168 phosphatidate cytidylyltransferase YP_004439156.1 723879 D 906968 CDS YP_004439157.1 332297235 10579073 complement(724490..725320) 1 NC_015500.1 KEGG: tde:TDE1445 hypothetical protein; SPTR: lipoprotein; IMG reference gene:2504919461; hypothetical protein 725320 10579073 Trebr_0583 Treponema brennaborense DSM 12168 hypothetical protein YP_004439157.1 724490 R 906968 CDS YP_004439158.1 332297236 10579074 725458..726150 1 NC_015500.1 COGs: COG5497 secreted protein; InterPro IPR018725; KEGG: tde:TDE1519 hypothetical protein; PFAM: Protein of unknown function DUF2259, secreted; SPTR: uncharacterized protein; IMG reference gene:2504919462; PFAM: Predicted secreted protein (DUF2259); hypothetical protein 726150 10579074 Trebr_0584 Treponema brennaborense DSM 12168 hypothetical protein YP_004439158.1 725458 D 906968 CDS YP_004439159.1 332297237 10579075 complement(726159..726596) 1 NC_015500.1 IMG reference gene:2504919463; hypothetical protein 726596 10579075 Trebr_0585 Treponema brennaborense DSM 12168 hypothetical protein YP_004439159.1 726159 R 906968 CDS YP_004439160.1 332297238 10579076 726697..727785 1 NC_015500.1 KEGG: sta:STHERM_c01870 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919464; hypothetical protein 727785 10579076 Trebr_0586 Treponema brennaborense DSM 12168 hypothetical protein YP_004439160.1 726697 D 906968 CDS YP_004439161.1 332297239 10579077 727801..728733 1 NC_015500.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: cpf:CPF_0279 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: aldose 1-epimerase; IMG reference gene:2504919465; PFAM: Aldose 1-epimerase; aldose-1-epimerase 728733 10579077 Trebr_0587 Treponema brennaborense DSM 12168 aldose-1-epimerase YP_004439161.1 727801 D 906968 CDS YP_004439162.1 332297240 10579078 728842..730725 1 NC_015500.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; HAMAP: Glucose-inhibited division protein A; InterPro IPR004416:IPR002218; KEGG: sta:STHERM_c02920 glucose-inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; IMG reference gene:2504919466; PFAM: Glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A; tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG 730725 10579078 Trebr_0588 Treponema brennaborense DSM 12168 tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG YP_004439162.1 728842 D 906968 CDS YP_004439163.1 332297241 10579079 complement(730854..731768) 1 NC_015500.1 COGs: COG1816 Adenosine deaminase; InterPro IPR001365; KEGG: tde:TDE0188 adenosine deaminase; PFAM: Adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: Adenosine deaminase; IMG reference gene:2504919467; PFAM: Adenosine/AMP deaminase; Adenosine deaminase 731768 10579079 Trebr_0589 Treponema brennaborense DSM 12168 Adenosine deaminase YP_004439163.1 730854 R 906968 CDS YP_004439164.1 332297242 10579080 complement(731857..733659) 1 NC_015500.1 COGs: COG1164 Oligoendopeptidase F; InterPro IPR013647:IPR001567:IPR004438; KEGG: tde:TDE2639 oligoendopeptidase F; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; Peptidase M3B, oligopeptidase F, N-terminal; SPTR: Oligoendopeptidase F; TIGRFAM: Peptidase M3B, oligoendopeptidase F; IMG reference gene:2504919468; PFAM: Oligopeptidase F; Peptidase family M3; TIGRFAM: oligoendopeptidase F; oligoendopeptidase F 733659 10579080 Trebr_0590 Treponema brennaborense DSM 12168 oligoendopeptidase F YP_004439164.1 731857 R 906968 CDS YP_004439165.1 332297243 10579081 complement(733828..735612) 1 NC_015500.1 COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014001:IPR001650:IPR011545:IPR018329; KEGG: tde:TDE0435 ATP-dependent DNA helicase RecQ; PFAM: DNA/RNA helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: DNA helicase, ATP-dependent, RecQ type, N-terminal; IMG reference gene:2504919469; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; RecQ familyATP-dependent DNA helicase 735612 10579081 Trebr_0591 Treponema brennaborense DSM 12168 RecQ familyATP-dependent DNA helicase YP_004439165.1 733828 R 906968 CDS YP_004439166.1 332297244 10579082 complement(735680..736990) 1 NC_015500.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE0664 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA family protein; IMG reference gene:2504919470; PFAM: OmpA family; OmpA/MotB domain-containing protein 736990 10579082 Trebr_0592 Treponema brennaborense DSM 12168 OmpA/MotB domain-containing protein YP_004439166.1 735680 R 906968 CDS YP_004439167.1 332297245 10579083 737139..737579 1 NC_015500.1 COGs: COG4741 secreted endonuclease distantly related to Holliday junction resolvase; InterPro IPR019287; KEGG: tde:TDE2613 hypothetical protein; PFAM: Holliday junction resolvase-like; SPTR: uncharacterized protein; IMG reference gene:2504919471; PFAM: Endonuclease related to archaeal Holliday junction resolvase; Holliday junction resolvase-like protein 737579 10579083 Trebr_0593 Treponema brennaborense DSM 12168 Holliday junction resolvase-like protein YP_004439167.1 737139 D 906968 CDS YP_004439168.1 332297246 10579084 complement(737555..739366) 1 NC_015500.1 COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633; KEGG: cth:Cthe_0408 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919472; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase/phosphodiesterase 739366 10579084 Trebr_0594 Treponema brennaborense DSM 12168 diguanylate cyclase/phosphodiesterase YP_004439168.1 737555 R 906968 CDS YP_004439169.1 332297247 10579085 complement(739406..740443) 1 NC_015500.1 COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR006059; KEGG: tpp:TPASS_0655 spermidine/putrescine ABC transporter, periplasmic binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Spermidine/putrescine ABC transporter, periplasmic binding protein; IMG reference gene:2504919473; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 740443 10579085 Trebr_0595 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004439169.1 739406 R 906968 CDS YP_004439170.1 332297248 10579086 complement(740515..741390) 1 NC_015500.1 COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: tpp:TPASS_0654 spermidine/putrescine ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Spermidine/putrescine ABC transporter, permease protein; IMG reference gene:2504919474; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 741390 10579086 Trebr_0596 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439170.1 740515 R 906968 CDS YP_004439171.1 332297249 10579087 complement(741390..742343) 1 NC_015500.1 COGs: COG1176 ABC-type spermidine/putrescine transport system permease component I; InterPro IPR000515; KEGG: tpp:TPASS_0653 spermidine/putrescine ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Spermidine/putrescine transport system permease protein PotB; IMG reference gene:2504919475; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 742343 10579087 Trebr_0597 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439171.1 741390 R 906968 CDS YP_004439172.1 332297250 10579088 complement(742340..743512) 1 NC_015500.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: tpp:TPASS_0652 spermidine/putrescine ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Spermidine/putrescine import ATP-binding protein PotA; IMG reference gene:2504919476; PFAM: ABC transporter; TOBE domain; TIGRFAM: spermidine/putrescine ABC transporter ATP-binding subunit; polyamine-transporting ATPase 743512 10579088 Trebr_0598 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004439172.1 742340 R 906968 CDS YP_004439173.1 332297251 10579090 complement(745946..746278) 1 NC_015500.1 COGs: COG1687 branched-chain amino acid permease (azaleucine resistance); InterPro IPR008407; KEGG: mac:MA3438 branched chain amino acid transport protein AzlD; PFAM: Branched-chain amino acid transport; SPTR: uncharacterized protein; IMG reference gene:2504919478; PFAM: Branched-chain amino acid transport protein (AzlD); branched-chain amino acid transport 746278 10579090 Trebr_0600 Treponema brennaborense DSM 12168 branched-chain amino acid transport YP_004439173.1 745946 R 906968 CDS YP_004439174.1 332297252 10579091 complement(746269..746973) 1 NC_015500.1 COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: mma:MM_3262 branched chain amino acid ABC transporter; PFAM: AzlC-like; SPTR: uncharacterized protein; IMG reference gene:2504919479; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC; AzlC family protein 746973 10579091 Trebr_0601 Treponema brennaborense DSM 12168 AzlC family protein YP_004439174.1 746269 R 906968 CDS YP_004439175.1 332297253 10579092 complement(747014..748807) 1 NC_015500.1 COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: ere:EUBREC_0891 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic region; PRIAM: Oligo-1,6-glucosidase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Glycosidases; IMG reference gene:2504919480; PFAM: Alpha amylase, catalytic domain; oligo-1,6-glucosidase 748807 10579092 Trebr_0602 Treponema brennaborense DSM 12168 oligo-1,6-glucosidase YP_004439175.1 747014 R 906968 CDS YP_004439176.1 332297254 10579093 complement(748892..749767) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR003313:IPR000005; KEGG: cbt:CLH_3331 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; AraC protein, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; IMG reference gene:2504919481; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; AraC family transcriptional regulator 749767 10579093 Trebr_0603 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439176.1 748892 R 906968 CDS YP_004439177.1 332297255 10579094 complement(749861..750811) 1 NC_015500.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: tde:TDE2286 MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; IMG reference gene:2504919482; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein; MazG family protein 750811 10579094 Trebr_0604 Treponema brennaborense DSM 12168 MazG family protein YP_004439177.1 749861 R 906968 CDS YP_004439178.1 332297256 10579095 complement(751001..751786) 1 NC_015500.1 COGs: COG0193 Peptidyl-tRNA hydrolase; HAMAP: Peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: tde:TDE0643 peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: Peptidyl-tRNA hydrolase; IMG reference gene:2504919483; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; Peptidyl-tRNA hydrolase 751786 10579095 Trebr_0605 Treponema brennaborense DSM 12168 Peptidyl-tRNA hydrolase YP_004439178.1 751001 R 906968 CDS YP_004439179.1 332297257 10579096 751824..752459 1 NC_015500.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; HAMAP: ATP-dependent Clp protease proteolytic subunit; InterPro IPR001907; KEGG: sta:STHERM_c05540 hypothetical protein; PFAM: Peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit 2; IMG reference gene:2504919484; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; ATP-dependent Clp protease proteolytic subunit 752459 10579096 Trebr_0606 Treponema brennaborense DSM 12168 ATP-dependent Clp protease proteolytic subunit YP_004439179.1 751824 D 906968 CDS YP_004439180.1 332297258 10579097 752597..753505 1 NC_015500.1 InterPro IPR000182; KEGG: ssm:Spirs_3745 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919485; PFAM: Acetyltransferase (GNAT) family; Uncharacterised protein family (UPF0158); GCN5-related N-acetyltransferase 753505 10579097 Trebr_0607 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004439180.1 752597 D 906968 CDS YP_004439181.1 332297259 10579098 753631..754461 1 NC_015500.1 InterPro IPR005580; KEGG: tde:TDE2592 DbpA RNA-binding domain-containing protein; PFAM: DbpA, RNA-binding; SPTR: DbpA RNA binding domain protein; IMG reference gene:2504919486; PFAM: DbpA RNA binding domain; DbpA RNA-binding domain-containing protein 754461 10579098 Trebr_0608 Treponema brennaborense DSM 12168 DbpA RNA-binding domain-containing protein YP_004439181.1 753631 D 906968 CDS YP_004439182.1 332297260 10579099 754476..755171 1 NC_015500.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: tde:TDE2403 metallo-beta-lactamase family protein; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504919487; PFAM: Metallo-beta-lactamase superfamily; metallo-beta-lactamase family protein 755171 10579099 Trebr_0609 Treponema brennaborense DSM 12168 metallo-beta-lactamase family protein YP_004439182.1 754476 D 906968 CDS YP_004439183.1 332297261 10579100 complement(755244..756911) 1 NC_015500.1 COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841:IPR008170:IPR004633; KEGG: tde:TDE1964 Na/Pi cotransporter family protein; PFAM: Na/Pi-cotransporter; PhoU; SPTR: Na/Pi cotransporter family protein; TIGRFAM: Na/Pi co-transporter II-related; IMG reference gene:2504919488; PFAM: Na+/Pi-cotransporter; PhoU domain; TIGRFAM: Na/Pi-cotransporter; Na/Pi-cotransporter II-like protein 756911 10579100 Trebr_0610 Treponema brennaborense DSM 12168 Na/Pi-cotransporter II-like protein YP_004439183.1 755244 R 906968 CDS YP_004439184.1 332297262 10579101 757045..757836 1 NC_015500.1 IMG reference gene:2504919489; hypothetical protein 757836 10579101 Trebr_0611 Treponema brennaborense DSM 12168 hypothetical protein YP_004439184.1 757045 D 906968 CDS YP_004439185.1 332297263 10579102 757861..758580 1 NC_015500.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: tde:TDE1578 phosphoesterase, PFAM: Metallophosphoesterase; SPTR: Phosphoesterase, ; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504919490; TIGRFAM: phosphoesterase, MJ0936 family; phosphodiesterase, MJ0936 family 758580 10579102 Trebr_0612 Treponema brennaborense DSM 12168 phosphodiesterase, MJ0936 family YP_004439185.1 757861 D 906968 CDS YP_004439186.1 332297264 10579103 758621..759043 1 NC_015500.1 KEGG: brm:Bmur_2690 periplasmic protein; SPTR: Periplasmic protein; IMG reference gene:2504919491; PFAM: Protein of unknown function (DUF2874); hypothetical protein 759043 10579103 Trebr_0613 Treponema brennaborense DSM 12168 hypothetical protein YP_004439186.1 758621 D 906968 CDS YP_004439187.1 332297265 10579104 complement(759055..759804) 1 NC_015500.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: mta:Moth_1128 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; IMG reference gene:2504919492; PFAM: ABC transporter; sulfate-transporting ATPase 759804 10579104 Trebr_0614 Treponema brennaborense DSM 12168 sulfate-transporting ATPase YP_004439187.1 759055 R 906968 CDS YP_004439188.1 332297266 10579105 complement(759797..760489) 1 NC_015500.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: aoe:Clos_0184 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; IMG reference gene:2504919493; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 760489 10579105 Trebr_0615 Treponema brennaborense DSM 12168 polar amino acid ABC transporter inner membrane subunit YP_004439188.1 759797 R 906968 CDS YP_004439189.1 332297267 10579106 760633..763449 1 NC_015500.1 COGs: COG0525 Valyl-tRNA synthetase; HAMAP: Valyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR019499:IPR002303; KEGG: tde:TDE1364 valyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; PRIAM: Valine--tRNA ligase; SPTR: Valyl-tRNA synthetase; TIGRFAM: Valyl-tRNA synthetase, class Ia; IMG reference gene:2504919494; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase; valyl-tRNA synthetase 763449 10579106 Trebr_0616 Treponema brennaborense DSM 12168 valyl-tRNA synthetase YP_004439189.1 760633 D 906968 CDS YP_004439190.1 332297268 10579107 763476..764054 1 NC_015500.1 KEGG: tde:TDE1690 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919495; hypothetical protein 764054 10579107 Trebr_0617 Treponema brennaborense DSM 12168 hypothetical protein YP_004439190.1 763476 D 906968 CDS YP_004439191.1 332297269 10579108 complement(764129..765259) 1 NC_015500.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: tte:TTE1215 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PRIAM: Glutaconyl-CoA decarboxylase; SPTR: Sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; IMG reference gene:2504919496; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; sodium ion-translocating decarboxylase subunit beta 765259 10579108 Trebr_0618 Treponema brennaborense DSM 12168 sodium ion-translocating decarboxylase subunit beta YP_004439191.1 764129 R 906968 CDS YP_004439192.1 332297270 10579109 765563..766561 1 NC_015500.1 COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR006424:IPR020828:IPR020829; KEGG: pdi:BDI_0287 glyceraldehyde 3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2504919497; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; glyceraldehyde-3-phosphate dehydrogenase 766561 10579109 Trebr_0619 Treponema brennaborense DSM 12168 glyceraldehyde-3-phosphate dehydrogenase YP_004439192.1 765563 D 906968 CDS YP_004439193.1 332297271 10579110 766745..768760 1 NC_015500.1 COGs: COG3292 periplasmic ligand-binding sensor domain; InterPro IPR011110; KEGG: tde:TDE1685 GGDEF domain-containing protein; PFAM: Two component regulator propeller; SPTR: GGDEF domain protein; IMG reference gene:2504919498; PFAM: Two component regulator propeller; two component regulator propeller domain-containing protein 768760 10579110 Trebr_0620 Treponema brennaborense DSM 12168 two component regulator propeller domain-containing protein YP_004439193.1 766745 D 906968 CDS YP_004439194.1 332297272 10579111 768757..769758 1 NC_015500.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR011123; KEGG: tde:TDE1685 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; Two component regulator three Y; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919499; PFAM: Y_Y_Y domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 769758 10579111 Trebr_0621 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004439194.1 768757 D 906968 CDS YP_004439195.1 332297273 10579112 complement(769873..770286) 1 NC_015500.1 IMG reference gene:2504919500; hypothetical protein 770286 10579112 Trebr_0622 Treponema brennaborense DSM 12168 hypothetical protein YP_004439195.1 769873 R 906968 CDS YP_004439196.1 332297274 10579113 complement(770288..772693) 1 NC_015500.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: ssm:Spirs_1297 AAA ATPase central domain protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Recombination factor protein RarA; IMG reference gene:2504919501; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); AAA ATPase central domain-containing protein 772693 10579113 Trebr_0623 Treponema brennaborense DSM 12168 AAA ATPase central domain-containing protein YP_004439196.1 770288 R 906968 CDS YP_004439197.1 332297275 10579114 complement(772715..773641) 1 NC_015500.1 KEGG: tde:TDE0015 lipoprotein; SPTR: lipoprotein; IMG reference gene:2504919502; hypothetical protein 773641 10579114 Trebr_0624 Treponema brennaborense DSM 12168 hypothetical protein YP_004439197.1 772715 R 906968 CDS YP_004439198.1 332297276 10579115 complement(773655..774242) 1 NC_015500.1 KEGG: tde:TDE0014 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919503; hypothetical protein 774242 10579115 Trebr_0625 Treponema brennaborense DSM 12168 hypothetical protein YP_004439198.1 773655 R 906968 CDS YP_004439199.1 332297277 10579116 774400..775278 1 NC_015500.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; HAMAP: Tetrahydrofolate dehydrogenase/cyclohydrolase; InterPro IPR000672:IPR020630:IPR020631; KEGG: tde:TDE0013 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methenyltetrahydrofolate cyclohydrolase; SPTR: Bifunctional protein FolD; IMG reference gene:2504919504; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; bifunctional protein folD 775278 10579116 Trebr_0626 Treponema brennaborense DSM 12168 bifunctional protein folD YP_004439199.1 774400 D 906968 CDS YP_004439200.1 332297278 10579117 775289..776125 1 NC_015500.1 COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: sta:STHERM_c09930 hypothetical protein; PFAM: Protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase I; IMG reference gene:2504919505; PFAM: Uncharacterized ACR, COG1469; GTP cyclohydrolase I 776125 10579117 Trebr_0627 Treponema brennaborense DSM 12168 GTP cyclohydrolase I YP_004439200.1 775289 D 906968 CDS YP_004439201.1 332297279 10579118 776133..777968 1 NC_015500.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: ipo:Ilyop_1336 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504919506; PFAM: Radical SAM superfamily; B12 binding domain; Radical SAM domain protein 777968 10579118 Trebr_0628 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004439201.1 776133 D 906968 CDS YP_004439202.1 332297280 10579119 778096..779508 1 NC_015500.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: tRNA-i(6)A37 modification enzyme MiaB; InterProIPR006463:IPR005839:IPR013848:IPR007197:IPR 002792:IPR006638; KEGG: tde:TDE1576 (dimethylallyl)adenosine tRNA methylthiotransferase; PFAM: Methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; TIGRFAM: tRNA-i(6)A37 modification enzyme MiaB; Methylthiotransferase; IMG reference gene:2504919507; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family; (dimethylallyl)adenosine tRNA methylthiotransferase MiaB 779508 10579119 Trebr_0629 Treponema brennaborense DSM 12168 (dimethylallyl)adenosine tRNA methylthiotransferase MiaB YP_004439202.1 778096 D 906968 CDS YP_004439203.1 332297281 10579120 779630..780058 1 NC_015500.1 KEGG: tde:TDE1615 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504919508; hypothetical protein 780058 10579120 Trebr_0630 Treponema brennaborense DSM 12168 hypothetical protein YP_004439203.1 779630 D 906968 CDS YP_004439204.1 332297282 10579121 780070..781140 1 NC_015500.1 InterPro IPR007730; KEGG: tpp:TPASS_0752 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; SPTR: uncharacterized protein; IMG reference gene:2504919509; PFAM: Sporulation related domain; sporulation domain-containing protein 781140 10579121 Trebr_0631 Treponema brennaborense DSM 12168 sporulation domain-containing protein YP_004439204.1 780070 D 906968 CDS YP_004439205.1 332297283 10579122 complement(781272..782771) 1 NC_015500.1 KEGG: tde:TDE0840 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919510; hypothetical protein 782771 10579122 Trebr_0632 Treponema brennaborense DSM 12168 hypothetical protein YP_004439205.1 781272 R 906968 CDS YP_004439206.1 332297284 10579123 complement(782784..783536) 1 NC_015500.1 InterPro IPR013216; KEGG: tde:TDE2499 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: uncharacterized protein; IMG reference gene:2504919511; PFAM: Methyltransferase domain; type 11 methyltransferase 783536 10579123 Trebr_0633 Treponema brennaborense DSM 12168 type 11 methyltransferase YP_004439206.1 782784 R 906968 CDS YP_004439207.1 332297285 10579124 783753..784181 1 NC_015500.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005823:IPR005822; KEGG: tde:TDE0852 50S ribosomal protein L13; PFAM: Ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: Ribosomal protein L13, bacterial-type; IMG reference gene:2504919512; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type; 50S ribosomal protein L13 784181 10579124 Trebr_0634 Treponema brennaborense DSM 12168 50S ribosomal protein L13 YP_004439207.1 783753 D 906968 CDS YP_004439208.1 332297286 10579125 784194..784586 1 NC_015500.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: tde:TDE0853 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2504919513; PFAM: Ribosomal protein S9/S16; 30S ribosomal protein S9 784586 10579125 Trebr_0635 Treponema brennaborense DSM 12168 30S ribosomal protein S9 YP_004439208.1 784194 D 906968 CDS YP_004439209.1 332297287 10579126 784586..785194 1 NC_015500.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: tde:TDE0854 recombination regulator RecX; PFAM: Regulatory protein RecX; SPTR: Regulatory protein recX; IMG reference gene:2504919514; PFAM: RecX family; regulatory protein RecX 785194 10579126 Trebr_0636 Treponema brennaborense DSM 12168 regulatory protein RecX YP_004439209.1 784586 D 906968 CDS YP_004439210.1 332297288 10579127 785370..785975 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR000551:IPR001789; KEGG: tde:TDE0855 DNA-binding response regulator; PFAM: Signal transduction response regulator, receiver region; HTH transcriptional regulator, MerR; SMART: Signal transduction response regulator, receiver region; SPTR: DNA-binding response regulator; IMG reference gene:2504919515; PFAM: Response regulator receiver domain; TIGRFAM: DNA binding domain, excisionase family; response regulator receiver protein 785975 10579127 Trebr_0637 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004439210.1 785370 D 906968 CDS YP_004439211.1 332297289 10579128 786112..787326 1 NC_015500.1 InterPro IPR010822:IPR001932; KEGG: cts:Ctha_0226 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-related; SPTR: Protein serine/threonine phosphatase; IMG reference gene:2504919516; PFAM: Stage II sporulation protein E (SpoIIE); Stage II sporulation protein E 787326 10579128 Trebr_0638 Treponema brennaborense DSM 12168 Stage II sporulation protein E YP_004439211.1 786112 D 906968 CDS YP_004439212.1 332297290 10579129 787373..787930 1 NC_015500.1 KEGG: ssm:Spirs_1317 anti-sigma regulatory factor, serine/threonine protein kinase; SPTR: uncharacterized protein; IMG reference gene:2504919517; anti-sigma regulatory factor, serine/threonine protein kinase 787930 10579129 Trebr_0639 Treponema brennaborense DSM 12168 anti-sigma regulatory factor, serine/threonine protein kinase YP_004439212.1 787373 D 906968 CDS YP_004439213.1 332297291 10579130 787927..789111 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR000644:IPR010822:IPR001932; KEGG: ssm:Spirs_1299 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; Cystathionine beta-synthase, core; SMART: Protein phosphatase 2C-related; SPTR: Protein serine/threonine phosphatase; IMG reference gene:2504919518; PFAM: CBS domain; Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 789111 10579130 Trebr_0640 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase YP_004439213.1 787927 D 906968 CDS YP_004439214.1 332297292 10579131 complement(789121..790233) 1 NC_015500.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: cth:Cthe_1421 signal peptide peptidase SppA, 36K type; PFAM: Peptidase S49; SPTR: Signal peptide peptidase SppA, 36K type; TIGRFAM: Peptidase S49, SppA; IMG reference gene:2504919519; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 36K type 790233 10579131 Trebr_0641 Treponema brennaborense DSM 12168 signal peptide peptidase SppA, 36K type YP_004439214.1 789121 R 906968 CDS YP_004439215.1 332297293 10579132 complement(790239..790889) 1 NC_015500.1 InterPro IPR010380; KEGG: bmd:BMD_3227 hypothetical protein; PFAM: Protein of unknown function DUF975; SPTR: uncharacterized protein; IMG reference gene:2504919520; PFAM: Protein of unknown function (DUF975); hypothetical protein 790889 10579132 Trebr_0642 Treponema brennaborense DSM 12168 hypothetical protein YP_004439215.1 790239 R 906968 CDS YP_004439216.1 332297294 10579133 complement(790948..791586) 1 NC_015500.1 COGs: COG1437 Adenylate cyclase class 2 (thermophilic); InterPro IPR008172; KEGG: bpo:BP951000_1449 adenylate cyclase; PFAM: Adenylate cyclase; SPTR: Adenylate cyclase, class 2 thermophilic; IMG reference gene:2504919521; PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB; adenylate cyclase 791586 10579133 Trebr_0643 Treponema brennaborense DSM 12168 adenylate cyclase YP_004439216.1 790948 R 906968 CDS YP_004439217.1 332297295 10579134 791710..793848 1 NC_015500.1 KEGG: cpi:Cpin_1999 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919522; hypothetical protein 793848 10579134 Trebr_0644 Treponema brennaborense DSM 12168 hypothetical protein YP_004439217.1 791710 D 906968 CDS YP_004439218.1 332297296 10579135 complement(793805..795229) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: amt:Amet_0545 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919523; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 795229 10579135 Trebr_0645 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004439218.1 793805 R 906968 CDS YP_004439219.1 332297297 10579136 795363..796235 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR003313:IPR000005:IPR018060; KEGG: amt:Amet_0544 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix, AraC type; AraC protein, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC domain; SPTR: Helix-turn-helix-domain containing protein, AraC type; IMG reference gene:2504919524; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; AraC family transcriptional regulator 796235 10579136 Trebr_0646 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439219.1 795363 D 906968 CDS YP_004439220.1 332297298 10579137 796389..797297 1 NC_015500.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; HAMAP: Dihydrodipicolinate synthase; InterPro IPR005263:IPR002220; KEGG: pcu:pc0686 dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; PRIAM: Dihydrodipicolinate synthase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: Dihydrodipicolinate synthase subfamily; IMG reference gene:2504919525; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase; Dihydrodipicolinate synthase 797297 10579137 Trebr_0647 Treponema brennaborense DSM 12168 Dihydrodipicolinate synthase YP_004439220.1 796389 D 906968 CDS YP_004439221.1 332297299 10579138 797308..798414 1 NC_015500.1 COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR005676:IPR000534:IPR012280; KEGG: cpy:Cphy_0426 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, dimerisation region; Semialdehyde dehydrogenase, NAD-binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking; IMG reference gene:2504919526; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (non-peptidoglycan organisms); aspartate-semialdehyde dehydrogenase 798414 10579138 Trebr_0648 Treponema brennaborense DSM 12168 aspartate-semialdehyde dehydrogenase YP_004439221.1 797308 D 906968 CDS YP_004439222.1 332297300 10579139 798454..799722 1 NC_015500.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183; KEGG: cni:Calni_0514 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; IMG reference gene:2504919527; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase; diaminopimelate decarboxylase 799722 10579139 Trebr_0649 Treponema brennaborense DSM 12168 diaminopimelate decarboxylase YP_004439222.1 798454 D 906968 CDS YP_004439223.1 332297301 10579140 complement(799674..801299) 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504919528; hypothetical protein 801299 10579140 Trebr_0650 Treponema brennaborense DSM 12168 hypothetical protein YP_004439223.1 799674 R 906968 CDS YP_004439224.1 332297302 10579141 complement(801315..802103) 1 NC_015500.1 COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: bav:BAV2947 NADH pyrophosphatase; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; PRIAM: NAD(+) diphosphatase; SPTR: NADH pyrophosphatase; IMG reference gene:2504919529; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NAD(+) diphosphatase 802103 10579141 Trebr_0651 Treponema brennaborense DSM 12168 NAD(+) diphosphatase YP_004439224.1 801315 R 906968 CDS YP_004439225.1 332297303 10579142 802380..802877 1 NC_015500.1 COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: cpr:CPR_0670 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: Phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; IMG reference gene:2504919530; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein; phosphoribosylaminoimidazole carboxylase catalytic subunit 802877 10579142 Trebr_0652 Treponema brennaborense DSM 12168 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_004439225.1 802380 D 906968 CDS YP_004439226.1 332297304 10579143 802874..803608 1 NC_015500.1 COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; InterPro IPR001636; KEGG: ckr:CKR_2384 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase; IMG reference gene:2504919531; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; Phosphoribosylaminoimidazole-succinocarboxamide synthase 803608 10579143 Trebr_0653 Treponema brennaborense DSM 12168 Phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004439226.1 802874 D 906968 CDS YP_004439227.1 332297305 10579144 803622..805073 1 NC_015500.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854:IPR000583:IPR000836; KEGG: cbb:CLD_1664 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; Phosphoribosyltransferase; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: Amidophosphoribosyl transferase; IMG reference gene:2504919532; PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase; amidophosphoribosyltransferase 805073 10579144 Trebr_0654 Treponema brennaborense DSM 12168 amidophosphoribosyltransferase YP_004439227.1 803622 D 906968 CDS YP_004439228.1 332297306 10579145 805160..806254 1 NC_015500.1 COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR000728:IPR010918; KEGG: cac:CA_C1393 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein; AIR synthase related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504919533; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase; phosphoribosylformylglycinamidine cyclo-ligase 806254 10579145 Trebr_0655 Treponema brennaborense DSM 12168 phosphoribosylformylglycinamidine cyclo-ligase YP_004439228.1 805160 D 906968 CDS YP_004439229.1 332297307 10579146 806247..807332 1 NC_015500.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR004607:IPR002376; KEGG: sta:STHERM_c12550 hypothetical protein; PFAM: Formyl transferase, N-terminal; PRIAM: Phosphoribosylglycinamide formyltransferase; SPTR: Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; TIGRFAM: Phosphoribosylglycinamide formyltransferase; IMG reference gene:2504919534; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; phosphoribosylglycinamide formyltransferase 807332 10579146 Trebr_0656 Treponema brennaborense DSM 12168 phosphoribosylglycinamide formyltransferase YP_004439229.1 806247 D 906968 CDS YP_004439230.1 332297308 10579147 complement(807415..808785) 1 NC_015500.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: cbf:CLI_2253 gluconate permease; PFAM: Gluconate transporter; SPTR: Gluconate transporter; TIGRFAM: Gluconate transporter; IMG reference gene:2504919535; PFAM: GntP family permease; TIGRFAM: gluconate transporter; gluconate transporter 808785 10579147 Trebr_0657 Treponema brennaborense DSM 12168 gluconate transporter YP_004439230.1 807415 R 906968 CDS YP_004439231.1 332297309 10579148 complement(808883..809884) 1 NC_015500.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: csh:Closa_3618 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504919536; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; 4-hydroxythreonine-4-phosphate dehydrogenase 809884 10579148 Trebr_0658 Treponema brennaborense DSM 12168 4-hydroxythreonine-4-phosphate dehydrogenase YP_004439231.1 808883 R 906968 CDS YP_004439232.1 332297310 10579149 complement(809921..811225) 1 NC_015500.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: csh:Closa_3619 type III effector Hrp-dependent outers domain protein; PFAM: Protein of unknown function, DUF1537; SPTR: Uncharacterized protein conserved in bacteria; IMG reference gene:2504919537; PFAM: Protein of unknown function, DUF1537; type III effector Hrp-dependent outer protein 811225 10579149 Trebr_0659 Treponema brennaborense DSM 12168 type III effector Hrp-dependent outer protein YP_004439232.1 809921 R 906968 CDS YP_004439233.1 332297311 10579150 complement(811231..811977) 1 NC_015500.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: csh:Closa_3616 transcriptional regulator, DeoR family; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504919538; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; Cro/CI family transcriptional regulator -like protein 811977 10579150 Trebr_0660 Treponema brennaborense DSM 12168 Cro/CI family transcriptional regulator -like protein YP_004439233.1 811231 R 906968 CDS YP_004439234.1 332297312 10579151 complement(812102..813499) 1 NC_015500.1 COGs: COG1160 GTPase; InterPro IPR005225:IPR002917; KEGG: elm:ELI_3378 hypothetical protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein; IMG reference gene:2504919539; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain; small GTP-binding protein 813499 10579151 Trebr_0661 Treponema brennaborense DSM 12168 small GTP-binding protein YP_004439234.1 812102 R 906968 CDS YP_004439235.1 332297313 10579152 complement(813501..814928) 1 NC_015500.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: elm:ELI_3377 thiamine biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SPTR: uncharacterized protein; IMG reference gene:2504919540; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH; biotin and thiamin synthesis associated protein 814928 10579152 Trebr_0662 Treponema brennaborense DSM 12168 biotin and thiamin synthesis associated protein YP_004439235.1 813501 R 906968 CDS YP_004439236.1 332297314 10579153 complement(814921..815997) 1 NC_015500.1 COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR006638; KEGG: bth:BT_1835 biotin synthase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Iron-only hydrogenase maturation protein HydE; IMG reference gene:2504919541; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE; Radical SAM domain protein 815997 10579153 Trebr_0663 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004439236.1 814921 R 906968 CDS YP_004439237.1 332297315 10579154 complement(815998..816249) 1 NC_015500.1 KEGG: ere:EUBREC_0233 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919542; TIGRFAM: iron-only hydrogenase system regulator; hypothetical protein 816249 10579154 Trebr_0664 Treponema brennaborense DSM 12168 hypothetical protein YP_004439237.1 815998 R 906968 CDS YP_004439238.1 332297316 10579155 816610..816999 1 NC_015500.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: dth:DICTH_0467 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504919543; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator 816999 10579155 Trebr_0665 Treponema brennaborense DSM 12168 GntR family transcriptional regulator YP_004439238.1 816610 D 906968 CDS YP_004439239.1 332297317 10579156 816996..817703 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: cbf:CLI_0638 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504919544; PFAM: ABC transporter; ABC transporter 817703 10579156 Trebr_0666 Treponema brennaborense DSM 12168 ABC transporter YP_004439239.1 816996 D 906968 CDS YP_004439240.1 332297318 10579157 817786..818565 1 NC_015500.1 KEGG: tde:TDE0166 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919545; hypothetical protein 818565 10579157 Trebr_0667 Treponema brennaborense DSM 12168 hypothetical protein YP_004439240.1 817786 D 906968 CDS YP_004439241.1 332297319 10579158 818687..819931 1 NC_015500.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR005861:IPR004839; KEGG: histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase; IMG reference gene:2504919546; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; histidinol-phosphate aminotransferase 819931 10579158 Trebr_0668 Treponema brennaborense DSM 12168 histidinol-phosphate aminotransferase YP_004439241.1 818687 D 906968 CDS YP_004439242.1 332297320 10579159 819928..820626 1 NC_015500.1 COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: tde:TDE2514 serine/threonine protein phosphatase family protein; PFAM: Metallophosphoesterase; SPTR: Serine/threonine protein phosphatase family protein; IMG reference gene:2504919547; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase 820626 10579159 Trebr_0669 Treponema brennaborense DSM 12168 metallophosphoesterase YP_004439242.1 819928 D 906968 CDS YP_004439243.1 332297321 10579160 820757..822061 1 NC_015500.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: ddf:DEFDS_0964 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase; IMG reference gene:2504919548; PFAM: AMP-binding enzyme; phenylacetate--CoA ligase 822061 10579160 Trebr_0670 Treponema brennaborense DSM 12168 phenylacetate--CoA ligase YP_004439243.1 820757 D 906968 CDS YP_004439244.1 332297322 10579161 822285..822701 1 NC_015500.1 COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: drt:Dret_1138 amino acid-binding ACT domain protein; PFAM: Amino acid-binding ACT; SPTR: Amino acid-binding ACT domain protein; IMG reference gene:2504919549; PFAM: ACT domain; amino acid-binding ACT domain-containing protein 822701 10579161 Trebr_0671 Treponema brennaborense DSM 12168 amino acid-binding ACT domain-containing protein YP_004439244.1 822285 D 906968 CDS YP_004439245.1 332297323 10579162 complement(822689..823699) 1 NC_015500.1 COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: tde:TDE2101 hypothetical protein; PFAM: Sulphatase-modifying factor; SPTR: uncharacterized protein; IMG reference gene:2504919550; PFAM: Formylglycine-generating sulfatase enzyme; sulfatase-modifying factor protein 823699 10579162 Trebr_0672 Treponema brennaborense DSM 12168 sulfatase-modifying factor protein YP_004439245.1 822689 R 906968 CDS YP_004439246.1 332297324 10579163 complement(823710..824753) 1 NC_015500.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: elm:ELI_0977 Mg2+ and Co2+ transporter; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Mg2+ and Co2+ transporter; IMG reference gene:2504919551; PFAM: CorA-like Mg2+ transporter protein; Mg2 transporter protein CorA family protein 824753 10579163 Trebr_0673 Treponema brennaborense DSM 12168 Mg2 transporter protein CorA family protein YP_004439246.1 823710 R 906968 CDS YP_004439247.1 332297325 10579164 825160..826260 1 NC_015500.1 COGs: COG0067 Glutamate synthase domain 1; InterPro IPR000583; KEGG: cth:Cthe_0197 glutamate synthase (NADPH) GltB1 subunit; PFAM: Glutamine amidotransferase, class-II; SPTR: uncharacterized protein; IMG reference gene:2504919552; PFAM: Glutamine amidotransferases class-II; glutamine amidotransferase 826260 10579164 Trebr_0674 Treponema brennaborense DSM 12168 glutamine amidotransferase YP_004439247.1 825160 D 906968 CDS YP_004439248.1 332297326 10579165 826251..827756 1 NC_015500.1 COGs: COG0069 Glutamate synthase domain 2; InterPro IPR001450:IPR002932; KEGG: cth:Cthe_0198 glutamate synthase (NADPH) GltB2 subunit; PFAM: Glutamate synthase, central-C; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Glutamate synthase (NADPH); SPTR: uncharacterized protein; IMG reference gene:2504919553; PFAM: Conserved region in glutamate synthase; Glutamate synthase (NADPH) 827756 10579165 Trebr_0675 Treponema brennaborense DSM 12168 Glutamate synthase (NADPH) YP_004439248.1 826251 D 906968 CDS YP_004439249.1 332297327 10579166 827771..828283 1 NC_015500.1 COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR001450; KEGG: cth:Cthe_0199 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: uncharacterized protein; IMG reference gene:2504919554; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 828283 10579166 Trebr_0676 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004439249.1 827771 D 906968 CDS YP_004439250.1 332297328 10579167 828280..829548 1 NC_015500.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: cth:Cthe_0200 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Ferredoxin--NAD(+) reductase; SPTR: uncharacterized protein; IMG reference gene:2504919555; PFAM: Pyridine nucleotide-disulphide oxidoreductase; ferredoxin--NAD(+) reductase 829548 10579167 Trebr_0677 Treponema brennaborense DSM 12168 ferredoxin--NAD(+) reductase YP_004439250.1 828280 D 906968 CDS YP_004439251.1 332297329 10579168 829551..830315 1 NC_015500.1 COGs: COG0070 Glutamate synthase domain 3; InterPro IPR002489; KEGG: cth:Cthe_0201 glutamate synthase (NADPH) GltB3 subunit; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: uncharacterized protein; IMG reference gene:2504919556; PFAM: GXGXG motif; glutamate synthase alpha subunit domain-containing protein 830315 10579168 Trebr_0678 Treponema brennaborense DSM 12168 glutamate synthase alpha subunit domain-containing protein YP_004439251.1 829551 D 906968 CDS YP_004439252.1 332297330 10579169 complement(830356..832194) 1 NC_015500.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; HAMAP: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; InterPro IPR005855:IPR000583:IPR001347; KEGG: amt:Amet_4299 glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: Sugar isomerase (SIS); Glutamine amidotransferase, class-II; PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; TIGRFAM: Glucosamine-fructose-6-phosphate aminotransferase, isomerising; IMG reference gene:2504919557; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing); glucosamine--fructose-6-phosphate aminotransferase 832194 10579169 Trebr_0679 Treponema brennaborense DSM 12168 glucosamine--fructose-6-phosphate aminotransferase YP_004439252.1 830356 R 906968 CDS YP_004439253.1 332297331 10579170 complement(832266..836165) 1 NC_015500.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212; KEGG: tde:TDE0085 ATP-dependent DNA helicase UvrD; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase, UvrD/Rep family; IMG reference gene:2504919558; PFAM: UvrD/REP helicase; UvrD/REP helicase 836165 10579170 Trebr_0680 Treponema brennaborense DSM 12168 UvrD/REP helicase YP_004439253.1 832266 R 906968 CDS YP_004439254.1 332297332 10579171 complement(836162..839212) 1 NC_015500.1 KEGG: tde:TDE0086 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919559; hypothetical protein 839212 10579171 Trebr_0681 Treponema brennaborense DSM 12168 hypothetical protein YP_004439254.1 836162 R 906968 CDS YP_004439255.1 332297333 10579172 839622..841685 1 NC_015500.1 KEGG: sta:STHERM_c15960 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919560; hypothetical protein 841685 10579172 Trebr_0682 Treponema brennaborense DSM 12168 hypothetical protein YP_004439255.1 839622 D 906968 CDS YP_004439256.1 332297334 10579173 841701..842144 1 NC_015500.1 IMG reference gene:2504919561; hypothetical protein 842144 10579173 Trebr_0683 Treponema brennaborense DSM 12168 hypothetical protein YP_004439256.1 841701 D 906968 CDS YP_004439257.1 332297335 10579174 842253..843989 1 NC_015500.1 COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: acp:A2cp1_4280 alpha amylase catalytic region; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region; IMG reference gene:2504919562; PFAM: Alpha amylase, catalytic domain; alpha amylase catalytic subunit 843989 10579174 Trebr_0684 Treponema brennaborense DSM 12168 alpha amylase catalytic subunit YP_004439257.1 842253 D 906968 CDS YP_004439258.1 332297336 10579175 844021..846846 1 NC_015500.1 COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR004193:IPR006047:IPR006589; KEGG: gym:GYMC10_0346 pullulanase, extracellular; PFAM: Glycosyl hydrolase, family 13, catalytic region; Glycoside hydrolase, family 13, N-terminal; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Pullulanase; IMG reference gene:2504919563; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; Bacterial pullanase-associated domain; TIGRFAM: pullulanase, extracellular, Gram-positive; pullulanase, type I; alpha amylase catalytic subunit 846846 10579175 Trebr_0685 Treponema brennaborense DSM 12168 alpha amylase catalytic subunit YP_004439258.1 844021 D 906968 CDS YP_004439259.1 332297337 10579176 846918..848108 1 NC_015500.1 COGs: COG2182 Maltose-binding periplasmic protein/domains; InterPro IPR006059; KEGG: family 1 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein, family 1; IMG reference gene:2504919564; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 848108 10579176 Trebr_0686 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004439259.1 846918 D 906968 CDS YP_004439260.1 332297338 10579177 848228..849610 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: xce:Xcel_2153 fructose-bisphosphate aldolase; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; IMG reference gene:2504919565; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 849610 10579177 Trebr_0687 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439260.1 848228 D 906968 CDS YP_004439261.1 332297339 10579178 849607..850524 1 NC_015500.1 COGs: COG3833 ABC-type maltose transport systems permease component; InterPro IPR000515; KEGG: tmt:Tmath_1953 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; IMG reference gene:2504919566; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 850524 10579178 Trebr_0688 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439261.1 849607 D 906968 CDS YP_004439262.1 332297340 10579179 850530..852191 1 NC_015500.1 COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: ppy:PPE_02348 alpha-amylase precursor (1,4-alpha-D-glucan glucanohydrolase); PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region; IMG reference gene:2504919567; PFAM: Alpha amylase, catalytic domain; alpha amylase catalytic subunit 852191 10579179 Trebr_0689 Treponema brennaborense DSM 12168 alpha amylase catalytic subunit YP_004439262.1 850530 D 906968 CDS YP_004439263.1 332297341 10579180 852338..853609 1 NC_015500.1 COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146; KEGG: cth:Cthe_0202 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: uncharacterized protein; IMG reference gene:2504919568; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; glutamine synthetase catalytic subunit 853609 10579180 Trebr_0690 Treponema brennaborense DSM 12168 glutamine synthetase catalytic subunit YP_004439263.1 852338 D 906968 CDS YP_004439264.1 332297342 10579181 853618..854187 1 NC_015500.1 InterPro IPR005561; KEGG: cth:Cthe_0203 response regulator receiver/ANTAR domain-containing protein; PFAM: ANTAR; SPTR: uncharacterized protein; IMG reference gene:2504919569; PFAM: Response regulator receiver domain; ANTAR domain; ANTAR domain-containing protein 854187 10579181 Trebr_0691 Treponema brennaborense DSM 12168 ANTAR domain-containing protein YP_004439264.1 853618 D 906968 CDS YP_004439265.1 332297343 10579182 854347..855087 1 NC_015500.1 COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: csh:Closa_3603 ATPase BadF/BadG/BcrA/BcrD type; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: ATPase BadF/BadG/BcrA/BcrD type; IMG reference gene:2504919570; PFAM: BadF/BadG/BcrA/BcrD ATPase family; BadF/BadG/BcrA/BcrD type ATPase 855087 10579182 Trebr_0692 Treponema brennaborense DSM 12168 BadF/BadG/BcrA/BcrD type ATPase YP_004439265.1 854347 D 906968 CDS YP_004439266.1 332297344 10579183 855317..857047 1 NC_015500.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR000583:IPR001962; KEGG: fjo:Fjoh_2251 asparagine synthetase B; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthetase B (Glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; IMG reference gene:2504919571; PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase 857047 10579183 Trebr_0693 Treponema brennaborense DSM 12168 asparagine synthase YP_004439266.1 855317 D 906968 CDS YP_004439267.1 332297345 10579184 857330..858280 1 NC_015500.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); HAMAP: Beta-ketoacyl-acyl carrier protein synthase III (FabH); InterPro IPR004655:IPR013751:IPR013747; KEGG: tde:TDE0602 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: Beta-ketoacyl-acyl carrier protein synthase III (FabH); IMG reference gene:2504919572; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; 3-oxoacyl-ACP synthase III 858280 10579184 Trebr_0694 Treponema brennaborense DSM 12168 3-oxoacyl-ACP synthase III YP_004439267.1 857330 D 906968 CDS YP_004439268.1 332297346 10579185 858274..859239 1 NC_015500.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043; KEGG: tde:TDE0601 malonyl CoA-acyl carrier protein transacylase, PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: Malonyl CoA-acyl carrier protein transacylase, ; IMG reference gene:2504919573; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; (acyl-carrier-protein) S-malonyltransferase 859239 10579185 Trebr_0695 Treponema brennaborense DSM 12168 (acyl-carrier-protein) S-malonyltransferase YP_004439268.1 858274 D 906968 CDS YP_004439269.1 332297347 10579186 859299..860042 1 NC_015500.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011284:IPR002198; KEGG: tde:TDE0598 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: 3-oxoacyl-(Acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; IMG reference gene:2504919574; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; 3-oxoacyl-ACP reductase 860042 10579186 Trebr_0696 Treponema brennaborense DSM 12168 3-oxoacyl-ACP reductase YP_004439269.1 859299 D 906968 CDS YP_004439270.1 332297348 10579187 860120..861364 1 NC_015500.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR017568:IPR014030:IPR014031; KEGG: tde:TDE0038 3-oxoacyl-(acyl-carrier-protein) synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 2; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; IMG reference gene:2504919575; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-ACP synthase II 861364 10579187 Trebr_0697 Treponema brennaborense DSM 12168 3-oxoacyl-ACP synthase II YP_004439270.1 860120 D 906968 CDS YP_004439271.1 332297349 10579188 861382..861813 1 NC_015500.1 COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: tde:TDE0823 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase, PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-(Acyl-carrier-protein) dehydratase, ; IMG reference gene:2504919576; PFAM: FabA-like domain; 3-hydroxyacyl-ACP dehydratase 861813 10579188 Trebr_0698 Treponema brennaborense DSM 12168 3-hydroxyacyl-ACP dehydratase YP_004439271.1 861382 D 906968 CDS YP_004439272.1 332297350 10579189 862414..863346 1 NC_015500.1 KEGG: cbt:CLH_2455 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919577; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 863346 10579189 Trebr_0699 Treponema brennaborense DSM 12168 hypothetical protein YP_004439272.1 862414 D 906968 CDS YP_004439273.1 332297351 10579190 863579..863890 1 NC_015500.1 IMG reference gene:2504919578; hypothetical protein 863890 10579190 Trebr_0700 Treponema brennaborense DSM 12168 hypothetical protein YP_004439273.1 863579 D 906968 CDS YP_004439274.1 332297352 10579191 863956..865290 1 NC_015500.1 KEGG: pct:PC1_4188 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919579; PFAM: Protein of unknown function (DUF1266); hypothetical protein 865290 10579191 Trebr_0701 Treponema brennaborense DSM 12168 hypothetical protein YP_004439274.1 863956 D 906968 CDS YP_004439275.1 332297353 10579192 865294..867303 1 NC_015500.1 KEGG: tde:TDE1728 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919580; hypothetical protein 867303 10579192 Trebr_0702 Treponema brennaborense DSM 12168 hypothetical protein YP_004439275.1 865294 D 906968 CDS YP_004439276.1 332297354 10579193 867385..868200 1 NC_015500.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR005670:IPR003439:IPR003593; KEGG: ckr:CKR_1247 hypothetical protein; PFAM: ABC transporter-like; PRIAM: Phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Phosphate ABC transporter; TIGRFAM: Phosphate transport system permease protein 1; IMG reference gene:2504919581; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein; phosphate ABC transporter ATPase 868200 10579193 Trebr_0703 Treponema brennaborense DSM 12168 phosphate ABC transporter ATPase YP_004439276.1 867385 D 906968 CDS YP_004439277.1 332297355 10579194 868289..868960 1 NC_015500.1 COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: sta:STHERM_c05380 transcriptional regulatory protein; PFAM: PhoU; SPTR: Phosphate transport system regulatory protein PhoU; TIGRFAM: PhoU; IMG reference gene:2504919582; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU; phosphate uptake regulator PhoU 868960 10579194 Trebr_0704 Treponema brennaborense DSM 12168 phosphate uptake regulator PhoU YP_004439277.1 868289 D 906968 CDS YP_004439278.1 332297356 10579195 869151..879872 1 NC_015500.1 InterPro IPR008619; KEGG: sta:STHERM_c00960 hypothetical protein; PFAM: Filamentous haemagglutinin, bacterial; SPTR: Hemagluttinin repeat-containing protein; IMG reference gene:2504919583; hemagluttinin repeat-containing protein 879872 10579195 Trebr_0705 Treponema brennaborense DSM 12168 hemagluttinin repeat-containing protein YP_004439278.1 869151 D 906968 CDS YP_004439279.1 332297357 10579196 complement(879937..880731) 1 NC_015500.1 COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: bhy:BHWA1_00398 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter; IMG reference gene:2504919584; PFAM: ABC transporter; Phosphonate-transporting ATPase 880731 10579196 Trebr_0706 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439279.1 879937 R 906968 CDS YP_004439280.1 332297358 10579197 complement(880725..881633) 1 NC_015500.1 COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: brm:Bmur_2585 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504919585; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 881633 10579197 Trebr_0707 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439280.1 880725 R 906968 CDS YP_004439281.1 332297359 10579198 881803..882696 1 NC_015500.1 COGs: COG0788 Formyltetrahydrofolate hydrolase; InterPro IPR004810:IPR002912:IPR002376; KEGG: fsu:Fisuc_0464 formyltetrahydrofolate deformylase; PFAM: Formyl transferase, N-terminal; Amino acid-binding ACT; PRIAM: Formyltetrahydrofolate deformylase; SPTR: Formyltetrahydrofolate deformylase; TIGRFAM: Formyltetrahydrofolate deformylase; IMG reference gene:2504919586; PFAM: ACT domain; Formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase; formyltetrahydrofolate deformylase 882696 10579198 Trebr_0708 Treponema brennaborense DSM 12168 formyltetrahydrofolate deformylase YP_004439281.1 881803 D 906968 CDS YP_004439282.1 332297360 10579199 complement(882794..883780) 1 NC_015500.1 COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: brm:Bmur_2584 protein of unknown function DUF534; PFAM: ABC transporter substrate binding protein; SPTR: uncharacterized protein; IMG reference gene:2504919587; PFAM: ABC transporter substrate binding protein; ABC transporter substrate-binding protein 883780 10579199 Trebr_0709 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004439282.1 882794 R 906968 CDS YP_004439283.1 332297361 10579200 884064..885347 1 NC_015500.1 COGs: COG0426 flavoprotein; KEGG: tde:TDE1078 metallo-beta-lactamase family protein; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504919588; PFAM: Metallo-beta-lactamase superfamily; metallo-beta-lactamase family protein 885347 10579200 Trebr_0710 Treponema brennaborense DSM 12168 metallo-beta-lactamase family protein YP_004439283.1 884064 D 906968 CDS YP_004439284.1 332297362 10579201 885426..885992 1 NC_015500.1 IMG reference gene:2504919589; hypothetical protein 885992 10579201 Trebr_0711 Treponema brennaborense DSM 12168 hypothetical protein YP_004439284.1 885426 D 906968 CDS YP_004439285.1 332297363 10579202 886007..887494 1 NC_015500.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: has:Halsa_0891 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504919590; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 887494 10579202 Trebr_0712 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004439285.1 886007 D 906968 CDS YP_004439286.1 332297364 10579203 887487..889019 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR018060; KEGG: csh:Closa_3814 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2504919591; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 889019 10579203 Trebr_0713 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439286.1 887487 D 906968 CDS YP_004439287.1 332297365 10579204 889227..890222 1 NC_015500.1 COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR004682:IPR018389; KEGG: has:Halsa_0893 TRAP dicarboxylate transporter, DctP subunit; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: uncharacterized protein; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; IMG reference gene:2504919592; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP 890222 10579204 Trebr_0714 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctP YP_004439287.1 889227 D 906968 CDS YP_004439288.1 332297366 10579205 890250..890852 1 NC_015500.1 COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: has:Halsa_0894 tripartite ATP-independent periplasmic transporter DctQ component; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: uncharacterized protein; IMG reference gene:2504919593; PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; tripartite AtP-independent periplasmic transporter subunit DctQ 890852 10579205 Trebr_0715 Treponema brennaborense DSM 12168 tripartite AtP-independent periplasmic transporter subunit DctQ YP_004439288.1 890250 D 906968 CDS YP_004439289.1 332297367 10579206 890845..892146 1 NC_015500.1 COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: sta:STHERM_c13530 transporter; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: uncharacterized protein; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; IMG reference gene:2504919594; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; TRAP dicarboxylate transporter subunit DctM 892146 10579206 Trebr_0716 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctM YP_004439289.1 890845 D 906968 CDS YP_004439290.1 332297368 10579207 892136..893143 1 NC_015500.1 COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR004682:IPR018389; KEGG: sta:STHERM_c13510 transporter; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; IMG reference gene:2504919595; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP 893143 10579207 Trebr_0717 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctP YP_004439290.1 892136 D 906968 CDS YP_004439291.1 332297369 10579208 complement(893215..894747) 1 NC_015500.1 COGs: COG1418 HD superfamily hydrolase; HAMAP: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; InterProIPR017705:IPR006675:IPR018111:IPR006674:IPR 004087:IPR003607; KEGG: tde:TDE0237 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; K Homology, type 1, subgroup; SMART: Metal-dependent phosphohydrolase, HD region; K Homology; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: 2,3-cyclic-nucleotide 2-phosphodiesterase; HDIG; IMG reference gene:2504919596; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG; 2,3 cyclic-nucleotide 2-phosphodiesterase 894747 10579208 Trebr_0718 Treponema brennaborense DSM 12168 2,3 cyclic-nucleotide 2-phosphodiesterase YP_004439291.1 893215 R 906968 CDS YP_004439292.1 332297370 10579209 894972..895790 1 NC_015500.1 COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: tde:TDE0647 chemotaxis protein methyltransferase; PFAM: MCP methyltransferase, CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: CheR methyltransferase, SAM binding domain; IMG reference gene:2504919597; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; CheR-type MCP methyltransferase 895790 10579209 Trebr_0719 Treponema brennaborense DSM 12168 CheR-type MCP methyltransferase YP_004439292.1 894972 D 906968 CDS YP_004439293.1 332297371 10579210 895803..896996 1 NC_015500.1 COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; HAMAP: Chemotaxis response regulator protein-glutamate methylesterase; InterPro IPR001789:IPR000673; KEGG: tde:TDE0648 protein-glutamate methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Chemotaxis response regulator protein-glutamate methylesterase; IMG reference gene:2504919598; PFAM: CheB methylesterase; Response regulator receiver domain; response regulator receiver modulated CheB methylesterase 896996 10579210 Trebr_0720 Treponema brennaborense DSM 12168 response regulator receiver modulated CheB methylesterase YP_004439293.1 895803 D 906968 CDS YP_004439294.1 332297372 10579211 complement(896968..897423) 1 NC_015500.1 IMG reference gene:2504919599; PFAM: Positive regulator of sigma(E), RseC/MucC; hypothetical protein 897423 10579211 Trebr_0721 Treponema brennaborense DSM 12168 hypothetical protein YP_004439294.1 896968 R 906968 CDS YP_004439295.1 332297373 10579212 complement(897416..897952) 1 NC_015500.1 InterPro IPR001440:IPR013105:IPR019734; KEGG: tde:TDE1536 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; IMG reference gene:2504919600; PFAM: Tetratricopeptide repeat; hypothetical protein 897952 10579212 Trebr_0722 Treponema brennaborense DSM 12168 hypothetical protein YP_004439295.1 897416 R 906968 CDS YP_004439296.1 332297374 10579213 complement(898046..899092) 1 NC_015500.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tde:TDE1537 polyprenyl synthetase family protein; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase family protein; IMG reference gene:2504919601; PFAM: Polyprenyl synthetase; polyprenyl synthetase 899092 10579213 Trebr_0723 Treponema brennaborense DSM 12168 polyprenyl synthetase YP_004439296.1 898046 R 906968 CDS YP_004439297.1 332297375 10579214 899164..899760 1 NC_015500.1 COGs: COG0293 23S rRNA methylase; HAMAP: Ribosomal RNA large subunit methyltransferase E; InterPro IPR002877; KEGG: tde:TDE1968 cell division protein FtsJ; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Ribosomal RNA large subunit methyltransferase E; IMG reference gene:2504919602; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ; ribosomal RNA large subunit methyltransferase E 899760 10579214 Trebr_0724 Treponema brennaborense DSM 12168 ribosomal RNA large subunit methyltransferase E YP_004439297.1 899164 D 906968 CDS YP_004439298.1 332297376 10579215 899770..900735 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: tde:TDE2318 LysM/M23/M37 peptidase; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: LysM domain/M23/M37 peptidase domain protein; IMG reference gene:2504919603; PFAM: Peptidase family M23; LysM domain; peptidase M23 900735 10579215 Trebr_0725 Treponema brennaborense DSM 12168 peptidase M23 YP_004439298.1 899770 D 906968 CDS YP_004439299.1 332297377 10579216 complement(900807..901394) 1 NC_015500.1 InterPro IPR001387:IPR013096; KEGG: ipo:Ilyop_0217 transcriptional regulator, MerR family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator; IMG reference gene:2504919604; PFAM: Cupin domain; Helix-turn-helix; helix-turn-helix domain-containing protein 901394 10579216 Trebr_0726 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439299.1 900807 R 906968 CDS YP_004439300.1 332297378 10579217 complement(901375..902463) 1 NC_015500.1 KEGG: tde:TDE1725 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919605; hypothetical protein 902463 10579217 Trebr_0727 Treponema brennaborense DSM 12168 hypothetical protein YP_004439300.1 901375 R 906968 CDS YP_004439301.1 332297379 10579218 902737..904548 1 NC_015500.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: acetolactate synthase large subunit; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504919606; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; acetolactate synthase large subunit, biosynthetic type 904548 10579218 Trebr_0728 Treponema brennaborense DSM 12168 acetolactate synthase large subunit, biosynthetic type YP_004439301.1 902737 D 906968 CDS YP_004439302.1 332297380 10579219 complement(904701..905333) 1 NC_015500.1 COGs: COG0563 Adenylate kinase and related kinase; HAMAP: Adenylate kinase; InterPro IPR006259:IPR000850:IPR007862; KEGG: tde:TDE1112 adenylate kinase; PFAM: Adenylate kinase; Adenylate kinase, zinc-finger lid region; SPTR: Adenylate kinase; TIGRFAM: Adenylate kinase, subfamily; IMG reference gene:2504919607; PFAM: Adenylate kinase, active site lid; Adenylate kinase; TIGRFAM: adenylate kinases; adenylate kinase 905333 10579219 Trebr_0729 Treponema brennaborense DSM 12168 adenylate kinase YP_004439302.1 904701 R 906968 CDS YP_004439303.1 332297381 10579220 complement(905448..905861) 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504919608; PFAM: Bacteriophage CI repressor helix-turn-helix domain; helix-turn-helix domain-containing protein 905861 10579220 Trebr_0730 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439303.1 905448 R 906968 CDS YP_004439304.1 332297382 10579223 906808..908250 1 NC_015500.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: cth:Cthe_2335 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2504919611; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 908250 10579223 Trebr_0733 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004439304.1 906808 D 906968 CDS YP_004439305.1 332297383 10579225 909351..910463 1 NC_015500.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: bfr:BF2581 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; IMG reference gene:2504919613; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase 910463 10579225 Trebr_0735 Treponema brennaborense DSM 12168 DegT/DnrJ/EryC1/StrS aminotransferase YP_004439305.1 909351 D 906968 CDS YP_004439306.1 332297384 10579226 910463..911668 1 NC_015500.1 COGs: COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); InterPro IPR003806; KEGG: carbamoyl-phosphate-synthetase; PFAM: ATP-grasp fold, DUF201-type; SPTR: carbamoyl-phosphate-synthetase; IMG reference gene:2504919614; PFAM: ATP-grasp domain; ATP-grasp fold domain-containing protein 911668 10579226 Trebr_0736 Treponema brennaborense DSM 12168 ATP-grasp fold domain-containing protein YP_004439306.1 910463 D 906968 CDS YP_004439307.1 332297385 10579227 911705..912208 1 NC_015500.1 InterPro IPR000182; KEGG: son:SO_3182 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; IMG reference gene:2504919615; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 912208 10579227 Trebr_0737 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004439307.1 911705 D 906968 CDS YP_004439308.1 332297386 10579228 912258..913205 1 NC_015500.1 KEGG: hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919616; hypothetical protein 913205 10579228 Trebr_0738 Treponema brennaborense DSM 12168 hypothetical protein YP_004439308.1 912258 D 906968 CDS YP_004439309.1 332297387 10579229 913193..913717 1 NC_015500.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dps:DP0040 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Pseudaminic acid biosynthesis N-acetyl transferase; IMG reference gene:2504919617; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: pseudaminic acid biosynthesis N-acetyl transferase; GCN5-related N-acetyltransferase 913717 10579229 Trebr_0739 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004439309.1 913193 D 906968 CDS YP_004439310.1 332297388 10579230 913788..914774 1 NC_015500.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR001173:IPR013747; KEGG: fsu:Fisuc_2659 glycosyl transferase family 2; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; Glycosyl transferase, family 2; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: Glycosyl transferase, group 2 family protein; IMG reference gene:2504919618; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; Glycosyl transferase family 2; 3-ketoacyl-ACP synthase III 914774 10579230 Trebr_0740 Treponema brennaborense DSM 12168 3-ketoacyl-ACP synthase III YP_004439310.1 913788 D 906968 CDS YP_004439311.1 332297389 10579231 914779..915777 1 NC_015500.1 KEGG: lbf:LBF_1962 glycosyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919619; hypothetical protein 915777 10579231 Trebr_0741 Treponema brennaborense DSM 12168 hypothetical protein YP_004439311.1 914779 D 906968 CDS YP_004439312.1 332297390 10579232 915764..916642 1 NC_015500.1 KEGG: lby:Lbys_1300 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919620; PFAM: Cryptococcal mannosyltransferase 1; hypothetical protein 916642 10579232 Trebr_0742 Treponema brennaborense DSM 12168 hypothetical protein YP_004439312.1 915764 D 906968 CDS YP_004439313.1 332297391 10579234 917514..918677 1 NC_015500.1 KEGG: pdi:BDI_0302 lipopolysaccharide biosynthesis related polysaccharide polymerase; SPTR: Predicted protein; IMG reference gene:2504919622; hypothetical protein 918677 10579234 Trebr_0744 Treponema brennaborense DSM 12168 hypothetical protein YP_004439313.1 917514 D 906968 CDS YP_004439314.1 332297392 10579235 918674..919435 1 NC_015500.1 COGs: COG3774 Mannosyltransferase OCH1; InterPro IPR007577; KEGG: pdi:BDI_1286 glycosyl transferase family protein; PFAM: Glycosyltransferase sugar-binding region containing DXD motif; SPTR: Glycosyltransferase family 32; IMG reference gene:2504919623; PFAM: Glycosyltransferase sugar-binding region containing DXD motif; glycosyltransferase family protein 919435 10579235 Trebr_0745 Treponema brennaborense DSM 12168 glycosyltransferase family protein YP_004439314.1 918674 D 906968 CDS YP_004439315.1 332297393 10579236 919432..920187 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504919624; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 920187 10579236 Trebr_0746 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004439315.1 919432 D 906968 CDS YP_004439316.1 332297394 10579238 complement(921522..922421) 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504919626; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 922421 10579238 Trebr_0748 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004439316.1 921522 R 906968 CDS YP_004439317.1 332297395 10579239 922826..923413 1 NC_015500.1 IMG reference gene:2504919627; hypothetical protein 923413 10579239 Trebr_0749 Treponema brennaborense DSM 12168 hypothetical protein YP_004439317.1 922826 D 906968 CDS YP_004439318.1 332297396 10579240 923483..923881 1 NC_015500.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sta:STHERM_c17560 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504919628; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein; queuosine biosynthesis protein QueD 923881 10579240 Trebr_0750 Treponema brennaborense DSM 12168 queuosine biosynthesis protein QueD YP_004439318.1 923483 D 906968 CDS YP_004439319.1 332297397 10579241 complement(923959..924720) 1 NC_015500.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; HAMAP: Imidazole glycerol phosphate synthase subunit hisF; InterPro IPR004651:IPR006062; KEGG: sta:STHERM_c15890 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: Histidine biosynthesis; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: Histidine biosynthesis, HisF; IMG reference gene:2504919629; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; imidazole glycerol phosphate synthase subunit hisF 924720 10579241 Trebr_0751 Treponema brennaborense DSM 12168 imidazole glycerol phosphate synthase subunit hisF YP_004439319.1 923959 R 906968 CDS YP_004439320.1 332297398 10579242 complement(924720..925367) 1 NC_015500.1 COGs: COG0118 Glutamine amidotransferase; HAMAP: Imidazole glycerol phosphate synthase, subunit H; InterPro IPR010139:IPR000991; KEGG: ssm:Spirs_1896 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase subunit hisH; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; IMG reference gene:2504919630; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; imidazole glycerol phosphate synthase subunit hisH 925367 10579242 Trebr_0752 Treponema brennaborense DSM 12168 imidazole glycerol phosphate synthase subunit hisH YP_004439320.1 924720 R 906968 CDS YP_004439321.1 332297399 10579243 complement(926098..927738) 1 NC_015500.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); HAMAP: 60 kDa chaperonin; InterPro IPR001844:IPR002423; KEGG: tpp:TPASS_0030 chaperonin GroEL; PFAM: Chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: Chaperonin Cpn60; IMG reference gene:2504919631; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL; 60 kDa chaperonin 927738 10579243 Trebr_0753 Treponema brennaborense DSM 12168 60 kDa chaperonin YP_004439321.1 926098 R 906968 CDS YP_004439322.1 332297400 10579244 927857..929458 1 NC_015500.1 COGs: COG0673 dehydrogenase and related protein; HAMAP: Ribonuclease H; InterPro IPR000683:IPR002156; KEGG: pjd:Pjdr2_2016 oxidoreductase domain protein; PFAM: Ribonuclease H; Oxidoreductase, N-terminal; PRIAM: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase., Ribonuclease H; SPTR: Oxidoreductase domain protein; IMG reference gene:2504919632; PFAM: RNase H; Oxidoreductase family, NAD-binding Rossmann fold; Ribonuclease H 929458 10579244 Trebr_0754 Treponema brennaborense DSM 12168 Ribonuclease H YP_004439322.1 927857 D 906968 CDS YP_004439323.1 332297401 10579245 complement(929530..930366) 1 NC_015500.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: aoe:Clos_0183 extracellular solute-binding protein; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; SPTR: Extracellular solute-binding protein family 3; IMG reference gene:2504919633; PFAM: Bacterial extracellular solute-binding proteins, family 3; ABC transporter substrate-binding protein 930366 10579245 Trebr_0755 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004439323.1 929530 R 906968 CDS YP_004439324.1 332297402 10579246 930543..931916 1 NC_015500.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967; KEGG: sth:STH2587 D-alanyl-D-alanine carboxypeptidase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: D-alanyl-D-alanine carboxypeptidase DacA; IMG reference gene:2504919634; PFAM: D-alanyl-D-alanine carboxypeptidase; serine-type D-Ala-D-Ala carboxypeptidase 931916 10579246 Trebr_0756 Treponema brennaborense DSM 12168 serine-type D-Ala-D-Ala carboxypeptidase YP_004439324.1 930543 D 906968 CDS YP_004439325.1 332297403 10579247 931983..933677 1 NC_015500.1 COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: cth:Cthe_2713 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504919635; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Dihydroxy-acid dehydratase 933677 10579247 Trebr_0757 Treponema brennaborense DSM 12168 Dihydroxy-acid dehydratase YP_004439325.1 931983 D 906968 CDS YP_004439326.1 332297404 10579248 933674..935383 1 NC_015500.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: cob:COB47_0622 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504919636; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; acetolactate synthase large subunit, biosynthetic type 935383 10579248 Trebr_0758 Treponema brennaborense DSM 12168 acetolactate synthase large subunit, biosynthetic type YP_004439326.1 933674 D 906968 CDS YP_004439327.1 332297405 10579249 935426..936658 1 NC_015500.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR019942:IPR004839; KEGG: cme:CMN323C unknown transaminase; PFAM: Aminotransferase, class I/II; PRIAM: LL-diaminopimelate aminotransferase; SPTR: uncharacterized protein; TIGRFAM: LL-diaminopimelate aminotransferase, plant-related; IMG reference gene:2504919637; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase; LL-diaminopimelate aminotransferase 936658 10579249 Trebr_0759 Treponema brennaborense DSM 12168 LL-diaminopimelate aminotransferase YP_004439327.1 935426 D 906968 CDS YP_004439328.1 332297406 10579250 complement(936758..937528) 1 NC_015500.1 IMG reference gene:2504919638; hypothetical protein 937528 10579250 Trebr_0760 Treponema brennaborense DSM 12168 hypothetical protein YP_004439328.1 936758 R 906968 CDS YP_004439329.1 332297407 10579251 complement(937525..938727) 1 NC_015500.1 IMG reference gene:2504919639; hypothetical protein 938727 10579251 Trebr_0761 Treponema brennaborense DSM 12168 hypothetical protein YP_004439329.1 937525 R 906968 CDS YP_004439330.1 332297408 10579252 938906..941404 1 NC_015500.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR010808:IPR004105:IPR003594:IPR 002545; KEGG: tde:TDE1491 chemotaxis protein CheA; PFAM: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, P2 response regulator-binding; Signal transduction histidine kinase, subgroup, homodimeric; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SPTR: P2 response regulator binding domain protein; IMG reference gene:2504919640; PFAM: P2 response regulator binding domain; CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; CheA signal transduction histidine kinase 941404 10579252 Trebr_0762 Treponema brennaborense DSM 12168 CheA signal transduction histidine kinase YP_004439330.1 938906 D 906968 CDS YP_004439331.1 332297409 10579253 941414..942844 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545:IPR000780; KEGG: tde:TDE1492 chemotaxis protein CheW; PFAM: MCP methyltransferase, CheR-type; CheW-like protein; SMART: CheW-like protein; MCP methyltransferase, CheR-type; SPTR: CheW; IMG reference gene:2504919641; PFAM: CheW-like domain; CheR methyltransferase, SAM binding domain; CheR-type MCP methyltransferase 942844 10579253 Trebr_0763 Treponema brennaborense DSM 12168 CheR-type MCP methyltransferase YP_004439331.1 941414 D 906968 CDS YP_004439332.1 332297410 10579254 942866..943330 1 NC_015500.1 COGs: COG1406 inhibitor of MCP methylation homolog of CheC; InterPro IPR007597; KEGG: sta:STHERM_c17210 chemotaxis protein CheC; PFAM: CheC-like protein; SPTR: chemotaxis protein CheC; IMG reference gene:2504919642; PFAM: CheC-like family; CheC domain-containing protein 943330 10579254 Trebr_0764 Treponema brennaborense DSM 12168 CheC domain-containing protein YP_004439332.1 942866 D 906968 CDS YP_004439333.1 332297411 10579255 943348..943782 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: tde:TDE1494 chemotaxis protein CheY; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver domain protein; IMG reference gene:2504919643; PFAM: Response regulator receiver domain; response regulator receiver protein 943782 10579255 Trebr_0765 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004439333.1 943348 D 906968 CDS YP_004439334.1 332297412 10579256 complement(943784..944485) 1 NC_015500.1 InterPro IPR001867; PFAM: Signal transduction response regulator, C-terminal; IMG reference gene:2504919644; PFAM: Transcriptional regulatory protein, C terminal; transcriptional regulator domain-containing protein 944485 10579256 Trebr_0766 Treponema brennaborense DSM 12168 transcriptional regulator domain-containing protein YP_004439334.1 943784 R 906968 CDS YP_004439335.1 332297413 10579258 complement(944855..945418) 1 NC_015500.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); HAMAP: Translation elongation factor P; InterPro IPR011768:IPR013185:IPR001059:IPR015365; KEGG: tde:TDE0968 translation elongation factor P; PFAM: Elongation factor P, C-terminal; Translation elongation factor, KOW-like; Translation elongation factor P/YeiP, central; SPTR: Elongation factor P; TIGRFAM: Translation elongation factor P; IMG reference gene:2504919646; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P; elongation factor P 945418 10579258 Trebr_0767 Treponema brennaborense DSM 12168 elongation factor P YP_004439335.1 944855 R 906968 CDS YP_004439336.1 332297414 10579259 complement(945491..946537) 1 NC_015500.1 COGs: COG2269 Truncated possibly inactive lysyl-tRNA synthetase (class II); InterPro IPR004364; KEGG: tde:TDE2282 tRNA synthetase, class II family protein; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); PRIAM: Lysine--tRNA ligase; SPTR: tRNA synthetase, class II family; IMG reference gene:2504919647; PFAM: tRNA synthetases class II (D, K and N); lysine--tRNA ligase 946537 10579259 Trebr_0768 Treponema brennaborense DSM 12168 lysine--tRNA ligase YP_004439336.1 945491 R 906968 CDS YP_004439337.1 332297415 10579260 946609..947316 1 NC_015500.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063; KEGG: tde:TDE0454 hypothetical protein; PFAM: PP-loop; SPTR: uncharacterized protein; IMG reference gene:2504919648; PFAM: PP-loop family; PP-loop domain-containing protein 947316 10579260 Trebr_0769 Treponema brennaborense DSM 12168 PP-loop domain-containing protein YP_004439337.1 946609 D 906968 CDS YP_004439338.1 332297416 10579261 947387..948070 1 NC_015500.1 KEGG: sta:STHERM_c02890 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919649; hypothetical protein 948070 10579261 Trebr_0770 Treponema brennaborense DSM 12168 hypothetical protein YP_004439338.1 947387 D 906968 CDS YP_004439339.1 332297417 10579262 948319..949167 1 NC_015500.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: lbf:LBF_2547 GGDEF domain receiver component of a two-component response regulator; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919650; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 949167 10579262 Trebr_0771 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004439339.1 948319 D 906968 CDS YP_004439340.1 332297418 10579263 949257..950366 1 NC_015500.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR004396:IPR002917:IPR013029; KEGG: tde:TDE0305 GTP-dependent nucleic acid-binding protein EngD; PFAM: Protein of unknown function DUF933; GTP-binding protein, HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: Conserved hypothetical protein CHP00092; IMG reference gene:2504919651; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF; GTP-binding protein YchF 950366 10579263 Trebr_0772 Treponema brennaborense DSM 12168 GTP-binding protein YchF YP_004439340.1 949257 D 906968 CDS YP_004439341.1 332297419 10579265 950830..951906 1 NC_015500.1 InterPro IPR005135; KEGG: tde:TDE2587 endonuclease/exonuclease/phosphatase family protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase family protein; IMG reference gene:2504919653; PFAM: Endonuclease/Exonuclease/phosphatase family; endonuclease/exonuclease/phosphatase 951906 10579265 Trebr_0774 Treponema brennaborense DSM 12168 endonuclease/exonuclease/phosphatase YP_004439341.1 950830 D 906968 CDS YP_004439342.1 332297420 10579266 951992..952222 1 NC_015500.1 KEGG: sta:STHERM_c21180 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919654; hypothetical protein 952222 10579266 Trebr_0775 Treponema brennaborense DSM 12168 hypothetical protein YP_004439342.1 951992 D 906968 CDS YP_004439343.1 332297421 10579268 complement(952519..953178) 1 NC_015500.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: gka:GK2449 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2504919656; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; 5-formyltetrahydrofolate cyclo-ligase 953178 10579268 Trebr_0776 Treponema brennaborense DSM 12168 5-formyltetrahydrofolate cyclo-ligase YP_004439343.1 952519 R 906968 CDS YP_004439344.1 332297422 10579269 complement(953175..954566) 1 NC_015500.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR007202; KEGG: dae:Dtox_0178 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2504919657; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; Fe-S cluster domain-containing protein 954566 10579269 Trebr_0777 Treponema brennaborense DSM 12168 Fe-S cluster domain-containing protein YP_004439344.1 953175 R 906968 CDS YP_004439345.1 332297423 10579270 complement(954563..955006) 1 NC_015500.1 COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: cpy:Cphy_3799 anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase-like; SPTR: uncharacterized protein; IMG reference gene:2504919658; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; anti-sigma regulatory factor, serine/threonine protein kinase 955006 10579270 Trebr_0778 Treponema brennaborense DSM 12168 anti-sigma regulatory factor, serine/threonine protein kinase YP_004439345.1 954563 R 906968 CDS YP_004439346.1 332297424 10579271 complement(955027..955374) 1 NC_015500.1 KEGG: csh:Closa_3389 DRTGG domain protein; SPTR: uncharacterized protein; IMG reference gene:2504919659; PFAM: DRTGG domain; DRTGG domain-containing protein 955374 10579271 Trebr_0779 Treponema brennaborense DSM 12168 DRTGG domain-containing protein YP_004439346.1 955027 R 906968 CDS YP_004439347.1 332297425 10579272 955748..957046 1 NC_015500.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: tde:TDE1256 HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: HD domain protein; IMG reference gene:2504919660; PFAM: HD domain; metal dependent phosphohydrolase 957046 10579272 Trebr_0780 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004439347.1 955748 D 906968 CDS YP_004439348.1 332297426 10579273 complement(957108..957869) 1 NC_015500.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: msi:Msm_1450 aldo/keto reductase family oxidoreductase; PFAM: Aldo/keto reductase; SPTR: Oxidoreductase, aldo/keto reductase family; IMG reference gene:2504919661; PFAM: Aldo/keto reductase family; aldo/keto reductase 957869 10579273 Trebr_0781 Treponema brennaborense DSM 12168 aldo/keto reductase YP_004439348.1 957108 R 906968 CDS YP_004439349.1 332297427 10579274 complement(957890..959236) 1 NC_015500.1 COGs: COG0423 Glycyl-tRNA synthetase (class II); InterPro IPR002315:IPR002314:IPR004154; KEGG: tde:TDE0020 glycyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; SPTR: Glycyl-tRNA synthetase; TIGRFAM: Glycyl-tRNA synthetase, alpha2 dimer; IMG reference gene:2504919662; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: glycyl-tRNA synthetase, dimeric type; glycyl-tRNA synthetase 959236 10579274 Trebr_0782 Treponema brennaborense DSM 12168 glycyl-tRNA synthetase YP_004439349.1 957890 R 906968 CDS YP_004439350.1 332297428 10579275 959380..960204 1 NC_015500.1 InterPro IPR005184; KEGG: mbn:Mboo_0798 protein of unknown function DUF306, MetA and HslJ; PFAM: Domain of unknown function DUF306, Meta/HslJ; SPTR: uncharacterized protein; IMG reference gene:2504919663; PFAM: META domain; hypothetical protein 960204 10579275 Trebr_0783 Treponema brennaborense DSM 12168 hypothetical protein YP_004439350.1 959380 D 906968 CDS YP_004439351.1 332297429 10579276 960262..960453 1 NC_015500.1 COGs: COG0227 Ribosomal protein L28; HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: tde:TDE0991 ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; IMG reference gene:2504919664; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; 50S ribosomal protein L28 960453 10579276 Trebr_0784 Treponema brennaborense DSM 12168 50S ribosomal protein L28 YP_004439351.1 960262 D 906968 CDS YP_004439352.1 332297430 10579277 complement(960591..962114) 1 NC_015500.1 COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: cno:NT01CX_1068 cardiolipin synthetase; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthase; IMG reference gene:2504919665; PFAM: Phospholipase D Active site motif; phospholipase D/Transphosphatidylase 962114 10579277 Trebr_0785 Treponema brennaborense DSM 12168 phospholipase D/Transphosphatidylase YP_004439352.1 960591 R 906968 CDS YP_004439353.1 332297431 10579278 complement(962119..963708) 1 NC_015500.1 InterPro IPR013229; KEGG: ssm:Spirs_1339 PEGA domain protein; PFAM: PEGA; SPTR: PEGA domain protein; IMG reference gene:2504919666; PFAM: PEGA domain; PEGA domain-containing protein 963708 10579278 Trebr_0786 Treponema brennaborense DSM 12168 PEGA domain-containing protein YP_004439353.1 962119 R 906968 CDS YP_004439354.1 332297432 10579279 complement(963721..965181) 1 NC_015500.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR006405:IPR015977; KEGG: tde:TDE0174 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: Nicotinate phosphoribosyltransferase IMG reference gene:2504919667; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase 965181 10579279 Trebr_0787 Treponema brennaborense DSM 12168 nicotinate phosphoribosyltransferase YP_004439354.1 963721 R 906968 CDS YP_004439355.1 332297433 10579280 complement(965323..966120) 1 NC_015500.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: rha:RHA1_ro01041 short-chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; IMG reference gene:2504919668; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 966120 10579280 Trebr_0788 Treponema brennaborense DSM 12168 short-chain dehydrogenase/reductase SDR YP_004439355.1 965323 R 906968 CDS YP_004439356.1 332297434 10579281 966261..968048 1 NC_015500.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR002318:IPR018164:IPR012947; KEGG: tde:TDE1659 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; SPTR: Alanyl-tRNA synthetase; TIGRFAM: Alanyl-tRNA synthetase, class IIc; IMG reference gene:2504919669; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase; alanyl-tRNA synthetase 968048 10579281 Trebr_0789 Treponema brennaborense DSM 12168 alanyl-tRNA synthetase YP_004439356.1 966261 D 906968 CDS YP_004439357.1 332297435 10579282 968161..969243 1 NC_015500.1 KEGG: tpp:TPASS_1016 basic membrane protein; SPTR: Basic membrane protein; IMG reference gene:2504919670; basic membrane protein 969243 10579282 Trebr_0790 Treponema brennaborense DSM 12168 basic membrane protein YP_004439357.1 968161 D 906968 CDS YP_004439358.1 332297436 10579283 969250..969666 1 NC_015500.1 COGs: COG0781 Transcription termination factor; HAMAP: N utilization substance protein B-like protein; InterPro IPR011605:IPR006027; KEGG: ssm:Spirs_2439 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: NusB antitermination factor; manually curated; IMG reference gene:2504919671; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB; NusB antitermination factor 969666 10579283 Trebr_0791 Treponema brennaborense DSM 12168 NusB antitermination factor YP_004439358.1 969250 D 906968 CDS YP_004439359.1 332297437 10579284 969686..971440 1 NC_015500.1 InterPro IPR019734; KEGG: tde:TDE1656 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504919672; hypothetical protein 971440 10579284 Trebr_0792 Treponema brennaborense DSM 12168 hypothetical protein YP_004439359.1 969686 D 906968 CDS YP_004439360.1 332297438 10579285 complement(971508..971774) 1 NC_015500.1 COGs: COG0234 Co-chaperonin GroES (HSP10); HAMAP: Chaperonin Cpn10, subgroup; InterPro IPR001476:IPR020818; KEGG: tpp:TPASS_1013 co-chaperonin GroES; PFAM: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; IMG reference gene:2504919673; PFAM: Chaperonin 10 Kd subunit; 10 kDa chaperonin 971774 10579285 Trebr_0793 Treponema brennaborense DSM 12168 10 kDa chaperonin YP_004439360.1 971508 R 906968 CDS YP_004439361.1 332297439 10579286 972148..973011 1 NC_015500.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR009042:IPR007627:IPR007624:IPR 007630; KEGG: ssm:Spirs_1715 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504919674; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 973011 10579286 Trebr_0794 Treponema brennaborense DSM 12168 RpoD subfamily RNA polymerase sigma-70 subunit YP_004439361.1 972148 D 906968 CDS YP_004439362.1 332297440 10579287 complement(973054..975288) 1 NC_015500.1 COGs: COG1200 RecG-like helicase; InterProIPR004609:IPR004365:IPR011545:IPR001650:IPR 014001; KEGG: tde:TDE2579 ATP-dependent DNA helicase RecG; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: DNA helicase, ATP-dependent, RecG; IMG reference gene:2504919675; PFAM: Helicase conserved C-terminal domain; OB-fold nucleic acid binding domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG; ATP-dependent DNA helicase RecG 975288 10579287 Trebr_0795 Treponema brennaborense DSM 12168 ATP-dependent DNA helicase RecG YP_004439362.1 973054 R 906968 CDS YP_004439363.1 332297441 10579288 complement(975317..975910) 1 NC_015500.1 InterPro IPR003425; KEGG: tpp:TPASS_0668 hypothetical integral membrane protein; PFAM: Protein of unknown function YGGT; SPTR: Yggt family protein; IMG reference gene:2504919676; PFAM: YGGT family; hypothetical protein 975910 10579288 Trebr_0796 Treponema brennaborense DSM 12168 hypothetical protein YP_004439363.1 975317 R 906968 CDS YP_004439364.1 332297442 10579289 complement(975932..979471) 1 NC_015500.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR004013:IPR011708:IPR004365:IPR 003141; KEGG: tde:TDE2786 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; IMG reference gene:2504919677; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: DNA-directed DNA polymerase III (polc); DNA polymerase III subunit alpha 979471 10579289 Trebr_0797 Treponema brennaborense DSM 12168 DNA polymerase III subunit alpha YP_004439364.1 975932 R 906968 CDS YP_004439365.1 332297443 10579290 979540..980598 1 NC_015500.1 COGs: COG1135 ABC-type metal ion transport system ATPase component; InterPro IPR003439:IPR018449:IPR003593; KEGG: fsu:Fisuc_1036 ABC transporter related protein; PFAM: ABC transporter-like; NIL domain; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Methionine import ATP-binding protein MetN; IMG reference gene:2504919678; PFAM: ABC transporter; NIL domain; polyamine-transporting ATPase 980598 10579290 Trebr_0798 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004439365.1 979540 D 906968 CDS YP_004439366.1 332297444 10579291 980705..981367 1 NC_015500.1 COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR000515; KEGG: fsu:Fisuc_1035 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: D-methionine transport system permease protein MetI; IMG reference gene:2504919679; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 981367 10579291 Trebr_0799 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439366.1 980705 D 906968 CDS YP_004439367.1 332297445 10579292 981460..982272 1 NC_015500.1 COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: fsu:Fisuc_1037 NlpA lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; IMG reference gene:2504919680; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; NLPA lipoprotein 982272 10579292 Trebr_0800 Treponema brennaborense DSM 12168 NLPA lipoprotein YP_004439367.1 981460 D 906968 CDS YP_004439368.1 332297446 10579293 complement(982358..983902) 1 NC_015500.1 KEGG: ssm:Spirs_0582 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919681; hypothetical protein 983902 10579293 Trebr_0801 Treponema brennaborense DSM 12168 hypothetical protein YP_004439368.1 982358 R 906968 CDS YP_004439369.1 332297447 10579294 complement(983936..985369) 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ssm:Spirs_2696 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Histidine kinase; IMG reference gene:2504919682; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 985369 10579294 Trebr_0802 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004439369.1 983936 R 906968 CDS YP_004439370.1 332297448 10579295 complement(985366..986067) 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ssm:Spirs_2695 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504919683; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; two component transcriptional regulator, winged helix family 986067 10579295 Trebr_0803 Treponema brennaborense DSM 12168 two component transcriptional regulator, winged helix family YP_004439370.1 985366 R 906968 CDS YP_004439371.1 332297449 10579296 complement(986069..986947) 1 NC_015500.1 KEGG: ssm:Spirs_2694 YD repeat-containing protein; SPTR: YD repeat-containing protein; IMG reference gene:2504919684; TIGRFAM: YD repeat (two copies); YD repeat-containing protein 986947 10579296 Trebr_0804 Treponema brennaborense DSM 12168 YD repeat-containing protein YP_004439371.1 986069 R 906968 CDS YP_004439372.1 332297450 10579297 complement(987202..987573) 1 NC_015500.1 IMG reference gene:2504919685; hypothetical protein 987573 10579297 Trebr_0805 Treponema brennaborense DSM 12168 hypothetical protein YP_004439372.1 987202 R 906968 CDS YP_004439373.1 332297451 10579298 complement(987641..988255) 1 NC_015500.1 InterPro IPR000782; PFAM: FAS1 domain; IMG reference gene:2504919686; beta-Ig-H3/fasciclin 988255 10579298 Trebr_0806 Treponema brennaborense DSM 12168 beta-Ig-H3/fasciclin YP_004439373.1 987641 R 906968 CDS YP_004439374.1 332297452 10579299 complement(988492..988845) 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504919687; PFAM: Bacteriophage CI repressor helix-turn-helix domain; helix-turn-helix domain-containing protein 988845 10579299 Trebr_0807 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439374.1 988492 R 906968 CDS YP_004439375.1 332297453 10579300 989209..990003 1 NC_015500.1 COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR013446:IPR005835; KEGG: cjn:ICDCCJ_1367 glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate cytidylyltransferase; SPTR: Glucose-1-phosphate cytidylyltransferase; TIGRFAM: Glucose-1-phosphate cytidylyltransferase; IMG reference gene:2504919688; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; glucose-1-phosphate cytidylyltransferase 990003 10579300 Trebr_0808 Treponema brennaborense DSM 12168 glucose-1-phosphate cytidylyltransferase YP_004439375.1 989209 D 906968 CDS YP_004439376.1 332297454 10579301 990004..991068 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: csh:Closa_0495 CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: CDP-glucose 4,6-dehydratase; SPTR: uncharacterized protein; TIGRFAM: CDP-glucose 4,6-dehydratase; IMG reference gene:2504919689; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase; CDP-glucose 4,6-dehydratase 991068 10579301 Trebr_0809 Treponema brennaborense DSM 12168 CDP-glucose 4,6-dehydratase YP_004439376.1 990004 D 906968 CDS YP_004439377.1 332297455 10579302 991085..992425 1 NC_015500.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: csh:Closa_0496 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; IMG reference gene:2504919690; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase 992425 10579302 Trebr_0810 Treponema brennaborense DSM 12168 DegT/DnrJ/EryC1/StrS aminotransferase YP_004439377.1 991085 D 906968 CDS YP_004439378.1 332297456 10579303 992425..994233 1 NC_015500.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766; KEGG: csh:Closa_0571 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; IMG reference gene:2504919691; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Acetolactate synthase 994233 10579303 Trebr_0811 Treponema brennaborense DSM 12168 Acetolactate synthase YP_004439378.1 992425 D 906968 CDS YP_004439379.1 332297457 10579304 994287..995891 1 NC_015500.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: glo:Glov_0787 pyruvate carboxyltransferase; PFAM: Pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; IMG reference gene:2504919692; PFAM: HMGL-like; pyruvate carboxyltransferase 995891 10579304 Trebr_0812 Treponema brennaborense DSM 12168 pyruvate carboxyltransferase YP_004439379.1 994287 D 906968 CDS YP_004439380.1 332297458 10579305 995895..996947 1 NC_015500.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: glo:Glov_0789 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; IMG reference gene:2504919693; PFAM: 3-dehydroquinate synthase; 3-dehydroquinate synthase 996947 10579305 Trebr_0813 Treponema brennaborense DSM 12168 3-dehydroquinate synthase YP_004439380.1 995895 D 906968 CDS YP_004439381.1 332297459 10579306 996982..997890 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mst:Msp_0537 nucleoside-diphosphate-sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; IMG reference gene:2504919694; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 997890 10579306 Trebr_0814 Treponema brennaborense DSM 12168 NAD-dependent epimerase/dehydratase YP_004439381.1 996982 D 906968 CDS YP_004439382.1 332297460 10579307 998403..999749 1 NC_015500.1 KEGG: pfl:PFL_5099 O-unit flippase, SPTR: O-unit flippase; IMG reference gene:2504919695; O-unit flippase 999749 10579307 Trebr_0815 Treponema brennaborense DSM 12168 O-unit flippase YP_004439382.1 998403 D 906968 CDS YP_004439383.1 332297461 10579308 999739..1000665 1 NC_015500.1 InterPro IPR001173; KEGG: coc:Coch_0702 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504919696; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 1000665 10579308 Trebr_0816 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004439383.1 999739 D 906968 CDS YP_004439384.1 332297462 10579309 1000805..1001587 1 NC_015500.1 KEGG: rba:RB343 hypothetical protein; SPTR: uncharacterized protein; manually curated; IMG reference gene:2504919697; hypothetical protein 1001587 10579309 Trebr_0817 Treponema brennaborense DSM 12168 hypothetical protein YP_004439384.1 1000805 D 906968 CDS YP_004439385.1 332297463 10579310 1001709..1002350 1 NC_015500.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: btb:BMB171_C3220 chloramphenicol acetyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919698; PFAM: Bacterial transferase hexapeptide (three repeats); hypothetical protein 1002350 10579310 Trebr_0818 Treponema brennaborense DSM 12168 hypothetical protein YP_004439385.1 1001709 D 906968 CDS YP_004439386.1 332297464 10579311 1002350..1003450 1 NC_015500.1 KEGG: coc:Coch_0700 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919699; hypothetical protein 1003450 10579311 Trebr_0819 Treponema brennaborense DSM 12168 hypothetical protein YP_004439386.1 1002350 D 906968 CDS YP_004439387.1 332297465 10579312 1003465..1004601 1 NC_015500.1 KEGG: bfr:BF1440 capsular polysaccharide polymerase; SPTR: capsular polysaccharide polymerase; IMG reference gene:2504919700; capsular polysaccharide polymerase 1004601 10579312 Trebr_0820 Treponema brennaborense DSM 12168 capsular polysaccharide polymerase YP_004439387.1 1003465 D 906968 CDS YP_004439388.1 332297466 10579313 1004681..1005787 1 NC_015500.1 InterPro IPR001296; KEGG: bth:BT_0478 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycoside transferase family 4; IMG reference gene:2504919701; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 1005787 10579313 Trebr_0821 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004439388.1 1004681 D 906968 CDS YP_004439389.1 332297467 10579314 1005781..1006632 1 NC_015500.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: ppn:Palpr_1287 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family protein; IMG reference gene:2504919702; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 1006632 10579314 Trebr_0822 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004439389.1 1005781 D 906968 CDS YP_004439390.1 332297468 10579315 1006647..1007141 1 NC_015500.1 IMG reference gene:2504919703; hypothetical protein 1007141 10579315 Trebr_0823 Treponema brennaborense DSM 12168 hypothetical protein YP_004439390.1 1006647 D 906968 CDS YP_004439391.1 332297469 10579316 1007267..1009018 1 NC_015500.1 COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR002320:IPR012947:IPR002314:IPR004154; KEGG: tde:TDE1090 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; IMG reference gene:2504919704; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; threonyl-tRNA synthetase 1009018 10579316 Trebr_0824 Treponema brennaborense DSM 12168 threonyl-tRNA synthetase YP_004439391.1 1007267 D 906968 CDS YP_004439392.1 332297470 10579317 complement(1009187..1009987) 1 NC_015500.1 KEGG: tde:TDE1091 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919705; hypothetical protein 1009987 10579317 Trebr_0825 Treponema brennaborense DSM 12168 hypothetical protein YP_004439392.1 1009187 R 906968 CDS YP_004439393.1 332297471 10579318 complement(1009984..1011141) 1 NC_015500.1 KEGG: tde:TDE2070 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919706; hypothetical protein 1011141 10579318 Trebr_0826 Treponema brennaborense DSM 12168 hypothetical protein YP_004439393.1 1009984 R 906968 CDS YP_004439394.1 332297472 10579319 complement(1011138..1012091) 1 NC_015500.1 IMG reference gene:2504919707; hypothetical protein 1012091 10579319 Trebr_0827 Treponema brennaborense DSM 12168 hypothetical protein YP_004439394.1 1011138 R 906968 CDS YP_004439395.1 332297473 10579320 1012145..1012789 1 NC_015500.1 COGs: COG2755 Lysophospholipase L1 and related esterase; InterPro IPR001087; KEGG: chd:Calhy_2099 lipolytic protein g-D-S-l family; PFAM: Lipase, GDSL; SPTR: Lipolytic enzyme; IMG reference gene:2504919708; PFAM: GDSL-like Lipase/Acylhydrolase; G-D-S-L family lipolytic protein 1012789 10579320 Trebr_0828 Treponema brennaborense DSM 12168 G-D-S-L family lipolytic protein YP_004439395.1 1012145 D 906968 CDS YP_004439396.1 332297474 10579321 1012889..1013293 1 NC_015500.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: ssm:Spirs_3238 preprotein translocase, YajC subunit; PFAM: YajC; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: YajC; IMG reference gene:2504919709; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; preprotein translocase subunit YajC 1013293 10579321 Trebr_0829 Treponema brennaborense DSM 12168 preprotein translocase subunit YajC YP_004439396.1 1012889 D 906968 CDS YP_004439397.1 332297475 10579322 1013317..1015053 1 NC_015500.1 COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR005791:IPR003335; KEGG: tde:TDE0681 preprotein translocase subunit SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Protein-export membrane protein SecD; TIGRFAM: SecD export membrane protein; SecD/SecF/SecDF export membrane protein; IMG reference gene:2504919710; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD 1015053 10579322 Trebr_0830 Treponema brennaborense DSM 12168 protein-export membrane protein SecD YP_004439397.1 1013317 D 906968 CDS YP_004439398.1 332297476 10579323 1015053..1016300 1 NC_015500.1 COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR005665:IPR003335; KEGG: tde:TDE0680 preprotein translocase subunit SecF; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Protein-export membrane protein SecF; TIGRFAM: SecF protein; SecD/SecF/SecDF export membrane protein; IMG reference gene:2504919711; PFAM: Protein export membrane protein; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; protein-export membrane protein SecF 1016300 10579323 Trebr_0831 Treponema brennaborense DSM 12168 protein-export membrane protein SecF YP_004439398.1 1015053 D 906968 CDS YP_004439399.1 332297477 10579324 1016461..1017393 1 NC_015500.1 COGs: COG0761 Penicillin tolerance protein; HAMAP: LytB protein; InterPro IPR003451; KEGG: tde:TDE1096 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: LytB protein; IMG reference gene:2504919712; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1017393 10579324 Trebr_0832 Treponema brennaborense DSM 12168 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_004439399.1 1016461 D 906968 CDS YP_004439400.1 332297478 10579325 complement(1017469..1017960) 1 NC_015500.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: amt:Amet_1540 YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK/aminoacyl-tRNA synthetase associated region; SPTR: Uncharacterized conserved protein; IMG reference gene:2504919713; PFAM: YbaK / prolyl-tRNA synthetases associated domain; YbaK/prolyl-tRNA synthetase associated domain-containing protein 1017960 10579325 Trebr_0833 Treponema brennaborense DSM 12168 YbaK/prolyl-tRNA synthetase associated domain-containing protein YP_004439400.1 1017469 R 906968 CDS YP_004439401.1 332297479 10579326 1018199..1019467 1 NC_015500.1 COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: tde:TDE1715 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504919714; PFAM: Phosphoglycerate kinase; Phosphoglycerate kinase 1019467 10579326 Trebr_0834 Treponema brennaborense DSM 12168 Phosphoglycerate kinase YP_004439401.1 1018199 D 906968 CDS YP_004439402.1 332297480 10579327 1019672..1020484 1 NC_015500.1 InterPro IPR014127; KEGG: pmz:HMPREF0659_A5225 conserved hypothetical protein TIGR02757; PFAM: Conserved hypothetical protein CHP02757; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02757; IMG reference gene:2504919715; PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein; hypothetical protein 1020484 10579327 Trebr_0835 Treponema brennaborense DSM 12168 hypothetical protein YP_004439402.1 1019672 D 906968 CDS YP_004439403.1 332297481 10579328 1020577..1022184 1 NC_015500.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR005675:IPR000891:IPR013709; KEGG: cth:Cthe_2519 alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; PRIAM: (R)-citramalate synthase; SPTR: 2-isopropylmalate synthase/homocitrate synthase family protein; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; IMG reference gene:2504919716; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; 2-isopropylmalate synthase/homocitrate synthase family protein 1022184 10579328 Trebr_0836 Treponema brennaborense DSM 12168 2-isopropylmalate synthase/homocitrate synthase family protein YP_004439403.1 1020577 D 906968 CDS YP_004439404.1 332297482 10579329 1022440..1022934 1 NC_015500.1 IMG reference gene:2504919717; hypothetical protein 1022934 10579329 Trebr_0837 Treponema brennaborense DSM 12168 hypothetical protein YP_004439404.1 1022440 D 906968 CDS YP_004439405.1 332297483 10579331 1023289..1024059 1 NC_015500.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: ele:Elen_1205 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504919719; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1024059 10579331 Trebr_0838 Treponema brennaborense DSM 12168 short-chain dehydrogenase/reductase SDR YP_004439405.1 1023289 D 906968 CDS YP_004439406.1 332297484 10579332 1024521..1026026 1 NC_015500.1 COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: tde:TDE2668 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; IMG reference gene:2504919720; PFAM: Serine hydroxymethyltransferase; glycine hydroxymethyltransferase 1026026 10579332 Trebr_0839 Treponema brennaborense DSM 12168 glycine hydroxymethyltransferase YP_004439406.1 1024521 D 906968 CDS YP_004439407.1 332297485 10579333 complement(1026125..1026643) 1 NC_015500.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; HAMAP: Adenine phosphoribosyl transferase; InterPro IPR005764:IPR000836; KEGG: tde:TDE1684 adenine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Adenine phosphoribosyltransferase; TIGRFAM: Adenine phosphoribosyl transferase; IMG reference gene:2504919721; PFAM: Phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase; Adenine phosphoribosyltransferase 1026643 10579333 Trebr_0840 Treponema brennaborense DSM 12168 Adenine phosphoribosyltransferase YP_004439407.1 1026125 R 906968 CDS YP_004439408.1 332297486 10579334 complement(1026671..1027588) 1 NC_015500.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: elm:ELI_0131 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504919722; PFAM: Prephenate dehydrogenase; prephenate dehydrogenase 1027588 10579334 Trebr_0841 Treponema brennaborense DSM 12168 prephenate dehydrogenase YP_004439408.1 1026671 R 906968 CDS YP_004439409.1 332297487 10579335 complement(1027585..1028616) 1 NC_015500.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: elm:ELI_0130 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504919723; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; phospho-2-dehydro-3-deoxyheptonate aldolase 1028616 10579335 Trebr_0842 Treponema brennaborense DSM 12168 phospho-2-dehydro-3-deoxyheptonate aldolase YP_004439409.1 1027585 R 906968 CDS YP_004439410.1 332297488 10579336 1029082..1030047 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: ccb:Clocel_0173 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504919724; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1030047 10579336 Trebr_0843 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439410.1 1029082 D 906968 CDS YP_004439411.1 332297489 10579337 1030136..1032613 1 NC_015500.1 InterPro IPR006638; KEGG: dfe:Dfer_2787 radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504919725; elongator protein 3/MiaB/NifB 1032613 10579337 Trebr_0844 Treponema brennaborense DSM 12168 elongator protein 3/MiaB/NifB YP_004439411.1 1030136 D 906968 CDS YP_004439412.1 332297490 10579338 1032675..1035545 1 NC_015500.1 COGs: COG0178 Excinuclease ATPase subunit; HAMAP: UvrABC system protein A; InterPro IPR004602:IPR003439:IPR003593; KEGG: tde:TDE1010 excinuclease ABC subunit A; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Excinuclease ABC subunit A; TIGRFAM: Excinuclease ABC, A subunit; IMG reference gene:2504919726; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit; UvrABC system protein A 1035545 10579338 Trebr_0845 Treponema brennaborense DSM 12168 UvrABC system protein A YP_004439412.1 1032675 D 906968 CDS YP_004439413.1 332297491 10579339 1035542..1038781 1 NC_015500.1 COGs: COG1452 Organic solvent tolerance protein OstA; KEGG: tde:TDE1011 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919727; hypothetical protein 1038781 10579339 Trebr_0846 Treponema brennaborense DSM 12168 hypothetical protein YP_004439413.1 1035542 D 906968 CDS YP_004439414.1 332297492 10579340 1038856..1040148 1 NC_015500.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027; KEGG: hmo:HM1_0999 glutamate synthase (nadph) beta chain, PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Glutamate synthase (NADPH); SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504919728; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutamate synthase (NADPH) 1040148 10579340 Trebr_0847 Treponema brennaborense DSM 12168 Glutamate synthase (NADPH) YP_004439414.1 1038856 D 906968 CDS YP_004439415.1 332297493 10579341 complement(1040270..1040527) 1 NC_015500.1 InterPro IPR007077; KEGG: clj:CLJU_c35100 hypothetical protein; PFAM: TfoX, C-terminal; SPTR: uncharacterized protein; IMG reference gene:2504919729; PFAM: TfoX C-terminal domain; TfoX domain-containing protein 1040527 10579341 Trebr_0848 Treponema brennaborense DSM 12168 TfoX domain-containing protein YP_004439415.1 1040270 R 906968 CDS YP_004439416.1 332297494 10579342 complement(1040643..1041023) 1 NC_015500.1 KEGG: ran:Riean_1760 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919730; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like; hypothetical protein 1041023 10579342 Trebr_0849 Treponema brennaborense DSM 12168 hypothetical protein YP_004439416.1 1040643 R 906968 CDS YP_004439417.1 332297495 10579343 complement(1041511..1043550) 1 NC_015500.1 COGs: COG0171 NAD synthase; InterPro IPR003694:IPR003010; KEGG: cpy:Cphy_3426 NAD+ synthetase; PFAM: NAD+ synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: uncharacterized protein; TIGRFAM: NAD+ synthase; IMG reference gene:2504919731; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase; NAD+ synthetase 1043550 10579343 Trebr_0850 Treponema brennaborense DSM 12168 NAD+ synthetase YP_004439417.1 1041511 R 906968 CDS YP_004439418.1 332297496 10579344 1043727..1044563 1 NC_015500.1 KEGG: cpy:Cphy_3620 sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504919732; PFAM: Sodium/hydrogen exchanger family; sodium/hydrogen exchanger 1044563 10579344 Trebr_0851 Treponema brennaborense DSM 12168 sodium/hydrogen exchanger YP_004439418.1 1043727 D 906968 CDS YP_004439419.1 332297497 10579345 complement(1044661..1045476) 1 NC_015500.1 COGs: COG2878 NADH:ubiquinone oxidoreductase subunit RnfB; InterPro IPR010207:IPR007202:IPR001450; KEGG: tde:TDE1894 ferredoxin; PFAM: Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur cluster-binding protein; TIGRFAM: Electron transport complex, RnfB; IMG reference gene:2504919733; PFAM: Fe-S cluster; 4Fe-4S binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; RnfABCDGE type electron transport complex subunit B 1045476 10579345 Trebr_0852 Treponema brennaborense DSM 12168 RnfABCDGE type electron transport complex subunit B YP_004439419.1 1044661 R 906968 CDS YP_004439420.1 332297498 10579346 complement(1045486..1046064) 1 NC_015500.1 COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; InterPro IPR011293:IPR003667; KEGG: tde:TDE0834 Na(+)-translocating NADH-quinone reductase, E subunit; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Na(+)-translocating NADH-quinone reductase subunit e (Na(+)-translocating nqr subunit e); TIGRFAM: Electron transport complex, RnfA; IMG reference gene:2504919734; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; RnfABCDGE type electron transport complex subunit A 1046064 10579346 Trebr_0853 Treponema brennaborense DSM 12168 RnfABCDGE type electron transport complex subunit A YP_004439420.1 1045486 R 906968 CDS YP_004439421.1 332297499 10579347 complement(1046061..1046684) 1 NC_015500.1 COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR010968:IPR003667; KEGG: tde:TDE0835 electron transport complex RsxE subunit; PFAM: Electron transport complex, Rnf/Nqr; SPTR: Na(+)-translocating NADH-quinone reductase subunit d (Na(+)-translocating nqr subunit d); TIGRFAM: Electron transport complex, RnfE; IMG reference gene:2504919735; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; RnfABCDGE type electron transport complex subunit E 1046684 10579347 Trebr_0854 Treponema brennaborense DSM 12168 RnfABCDGE type electron transport complex subunit E YP_004439421.1 1046061 R 906968 CDS YP_004439422.1 332297500 10579348 complement(1046695..1047816) 1 NC_015500.1 COGs: COG4659 NADH:ubiquinone oxidoreductase subunit RnfG; InterPro IPR007329; KEGG: tde:TDE0836 Na(+)-translocating NADH-quinone reductase, C subunit; PFAM: FMN-binding; SPTR: Na(+)-translocating NADH-quinone reductase, C subunit; IMG reference gene:2504919736; PFAM: FMN-binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; FMN-binding domain-containing protein 1047816 10579348 Trebr_0855 Treponema brennaborense DSM 12168 FMN-binding domain-containing protein YP_004439422.1 1046695 R 906968 CDS YP_004439423.1 332297501 10579349 complement(1047813..1048781) 1 NC_015500.1 COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR011303:IPR004338; KEGG: tde:TDE0837 Na(+)-translocating NADH-quinone reductase, B subunit; PFAM: NADH-quinone reductase NQR2/RnfD; SPTR: Na(+)-translocating NADH-quinone reductase, B subunit; TIGRFAM: Electron transport complex, RnfD; IMG reference gene:2504919737; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; RnfABCDGE type electron transport complex subunit D 1048781 10579349 Trebr_0856 Treponema brennaborense DSM 12168 RnfABCDGE type electron transport complex subunit D YP_004439423.1 1047813 R 906968 CDS YP_004439424.1 332297502 10579350 complement(1048782..1050185) 1 NC_015500.1 COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; HAMAP: Electron transport complex protein rnfC; InterPro IPR010208:IPR011538; KEGG: tde:TDE0838 Na(+)-translocating NADH-quinone reductase, A subunit; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; SPTR: Na(+)-translocating NADH-quinone reductase, A subunit; TIGRFAM: Electron transport complex, RnfC; IMG reference gene:2504919738; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; electron transport complex protein RnfC 1050185 10579350 Trebr_0857 Treponema brennaborense DSM 12168 electron transport complex protein RnfC YP_004439424.1 1048782 R 906968 CDS YP_004439425.1 332297503 10579351 1050254..1051270 1 NC_015500.1 KEGG: tde:TDE2028 OmpA family protein; SPTR: OmpA family protein; IMG reference gene:2504919739; OmpA family protein 1051270 10579351 Trebr_0858 Treponema brennaborense DSM 12168 OmpA family protein YP_004439425.1 1050254 D 906968 CDS YP_004439426.1 332297504 10579352 1051267..1054401 1 NC_015500.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE2028 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA family protein; IMG reference gene:2504919740; PFAM: OmpA family; OmpA/MotB domain-containing protein 1054401 10579352 Trebr_0859 Treponema brennaborense DSM 12168 OmpA/MotB domain-containing protein YP_004439426.1 1051267 D 906968 CDS YP_004439427.1 332297505 10579353 1054589..1055818 1 NC_015500.1 COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: dap:Dacet_1733 diguanylate phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; SMART: Diguanylate phosphodiesterase, predicted; SPTR: Diguanylate phosphodiesterase; IMG reference gene:2504919741; PFAM: EAL domain; diguanylate phosphodiesterase 1055818 10579353 Trebr_0860 Treponema brennaborense DSM 12168 diguanylate phosphodiesterase YP_004439427.1 1054589 D 906968 CDS YP_004439428.1 332297506 10579354 1055827..1057206 1 NC_015500.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; HAMAP: 3-phosphoshikimate 1-carboxyvinyltransferase, subgroup; InterPro IPR006264:IPR001986; KEGG: sta:STHERM_c03680 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, core; PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase 2; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, subgroup; IMG reference gene:2504919742; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; 3-phosphoshikimate 1-carboxyvinyltransferase 1057206 10579354 Trebr_0861 Treponema brennaborense DSM 12168 3-phosphoshikimate 1-carboxyvinyltransferase YP_004439428.1 1055827 D 906968 CDS YP_004439429.1 332297507 10579355 1057244..1058701 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: sta:STHERM_c20950 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: methyl-accepting chemotaxis protein; IMG reference gene:2504919743; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1058701 10579355 Trebr_0862 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439429.1 1057244 D 906968 CDS YP_004439430.1 332297508 10579356 complement(1058844..1059932) 1 NC_015500.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544; KEGG: sta:STHERM_c01780 branched-chain-amino-acid aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain amino acid aminotransferase; TIGRFAM: Branched-chain amino acid aminotransferase II; IMG reference gene:2504919744; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II; branched-chain amino acid aminotransferase 1059932 10579356 Trebr_0863 Treponema brennaborense DSM 12168 branched-chain amino acid aminotransferase YP_004439430.1 1058844 R 906968 CDS YP_004439431.1 332297509 10579357 complement(1060008..1060169) 1 NC_015500.1 IMG reference gene:2504919745; hypothetical protein 1060169 10579357 Trebr_0864 Treponema brennaborense DSM 12168 hypothetical protein YP_004439431.1 1060008 R 906968 CDS YP_004439432.1 332297510 10579358 complement(1060166..1061575) 1 NC_015500.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tpp:TPASS_0624 hypothetical protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA family protein; IMG reference gene:2504919746; PFAM: OmpA family; OmpA/MotB domain-containing protein 1061575 10579358 Trebr_0865 Treponema brennaborense DSM 12168 OmpA/MotB domain-containing protein YP_004439432.1 1060166 R 906968 CDS YP_004439433.1 332297511 10579359 complement(1061582..1062850) 1 NC_015500.1 InterPro IPR008258:IPR018392:IPR002482; KEGG: tde:TDE2149 Slt family transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Transglycosylase, SLT family; IMG reference gene:2504919747; PFAM: Transglycosylase SLT domain; LysM domain; Lytic transglycosylase catalytic 1062850 10579359 Trebr_0866 Treponema brennaborense DSM 12168 Lytic transglycosylase catalytic YP_004439433.1 1061582 R 906968 CDS YP_004439434.1 332297512 10579360 complement(1062847..1063890) 1 NC_015500.1 KEGG: tde:TDE2150 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919748; hypothetical protein 1063890 10579360 Trebr_0867 Treponema brennaborense DSM 12168 hypothetical protein YP_004439434.1 1062847 R 906968 CDS YP_004439435.1 332297513 10579361 1063974..1064591 1 NC_015500.1 IMG reference gene:2504919749; hypothetical protein 1064591 10579361 Trebr_0868 Treponema brennaborense DSM 12168 hypothetical protein YP_004439435.1 1063974 D 906968 CDS YP_004439436.1 332297514 10579362 1064594..1066339 1 NC_015500.1 InterPro IPR001440:IPR019734; KEGG: tde:TDE1053 lipoprotein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Lipoprotein, ; IMG reference gene:2504919750; hypothetical protein 1066339 10579362 Trebr_0869 Treponema brennaborense DSM 12168 hypothetical protein YP_004439436.1 1064594 D 906968 CDS YP_004439437.1 332297515 10579363 1066426..1066584 1 NC_015500.1 COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: tde:TDE1052 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; IMG reference gene:2504919751; PFAM: Rubredoxin; rubredoxin-type Fe(Cys)4 protein 1066584 10579363 Trebr_0870 Treponema brennaborense DSM 12168 rubredoxin-type Fe(Cys)4 protein YP_004439437.1 1066426 D 906968 CDS YP_004439438.1 332297516 10579364 complement(1066670..1067902) 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tde:TDE2283 permease, PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Permease, ; IMG reference gene:2504919752; PFAM: Predicted permease; hypothetical protein 1067902 10579364 Trebr_0871 Treponema brennaborense DSM 12168 hypothetical protein YP_004439438.1 1066670 R 906968 CDS YP_004439439.1 332297517 10579365 complement(1067895..1068599) 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tpp:TPASS_0964 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Macrolide export ATP-binding/permease protein MacB; IMG reference gene:2504919753; PFAM: ABC transporter; Phosphonate-transporting ATPase 1068599 10579365 Trebr_0872 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439439.1 1067895 R 906968 CDS YP_004439440.1 332297518 10579366 complement(1068604..1069578) 1 NC_015500.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: tpp:TPASS_0965 possible membrane fusion protein; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504919754; PFAM: HlyD family secretion protein; RND family efflux transporter MFP subunit 1069578 10579366 Trebr_0873 Treponema brennaborense DSM 12168 RND family efflux transporter MFP subunit YP_004439440.1 1068604 R 906968 CDS YP_004439441.1 332297519 10579367 complement(1069648..1071093) 1 NC_015500.1 KEGG: tde:TDE2285 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919755; hypothetical protein 1071093 10579367 Trebr_0874 Treponema brennaborense DSM 12168 hypothetical protein YP_004439441.1 1069648 R 906968 CDS YP_004439442.1 332297520 10579368 1071274..1072902 1 NC_015500.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR004468:IPR017456:IPR000991; KEGG: sta:STHERM_c21900 CTP synthase; PFAM: CTP synthase, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; IMG reference gene:2504919756; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase; CTP synthase 1072902 10579368 Trebr_0875 Treponema brennaborense DSM 12168 CTP synthase YP_004439442.1 1071274 D 906968 CDS YP_004439443.1 332297521 10579369 1072902..1073486 1 NC_015500.1 KEGG: tde:TDE0646 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919757; hypothetical protein 1073486 10579369 Trebr_0876 Treponema brennaborense DSM 12168 hypothetical protein YP_004439443.1 1072902 D 906968 CDS YP_004439444.1 332297522 10579370 1073483..1074133 1 NC_015500.1 InterPro IPR005653; KEGG: tde:TDE0645 hypothetical protein; PFAM: OstA-like protein; SPTR: uncharacterized protein; IMG reference gene:2504919758; PFAM: OstA-like protein; OstA family protein 1074133 10579370 Trebr_0877 Treponema brennaborense DSM 12168 OstA family protein YP_004439444.1 1073483 D 906968 CDS YP_004439445.1 332297523 10579371 1074126..1074884 1 NC_015500.1 COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tde:TDE0644 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504919759; PFAM: ABC transporter; sulfate-transporting ATPase 1074884 10579371 Trebr_0878 Treponema brennaborense DSM 12168 sulfate-transporting ATPase YP_004439445.1 1074126 D 906968 CDS YP_004439446.1 332297524 10579372 1074908..1075366 1 NC_015500.1 COGs: COG2703 Hemerythrin; InterPro IPR012827:IPR012312; KEGG: brm:Bmur_1400 hemerythrin-like metal-binding protein; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Hemerythrin-like metal-binding protein; TIGRFAM: Haemerythrin-like, metal-binding; IMG reference gene:2504919760; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein 1075366 10579372 Trebr_0879 Treponema brennaborense DSM 12168 hemerythrin-like metal-binding protein YP_004439446.1 1074908 D 906968 CDS YP_004439447.1 332297525 10579373 1075385..1075837 1 NC_015500.1 COGs: COG2703 Hemerythrin; InterPro IPR012827:IPR012312; KEGG: bpo:BP951000_1676 hemerythrin; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Hemerythrin family protein; TIGRFAM: Haemerythrin-like, metal-binding; IMG reference gene:2504919761; PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein 1075837 10579373 Trebr_0880 Treponema brennaborense DSM 12168 hemerythrin-like metal-binding protein YP_004439447.1 1075385 D 906968 CDS YP_004439448.1 332297526 10579374 1075900..1077720 1 NC_015500.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase, type IIA, subunit B, region 2; ATP-binding region, ATPase-like; SMART: DNA topoisomerase, type IIA, subunit B or N-terminal; SPTR: DNA topoisomerase 4 subunit B; IMG reference gene:2504919762; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; DNA topoisomerase type IIA subunit B domain-containing protein 1077720 10579374 Trebr_0881 Treponema brennaborense DSM 12168 DNA topoisomerase type IIA subunit B domain-containing protein YP_004439448.1 1075900 D 906968 CDS YP_004439449.1 332297527 10579375 1077741..1079687 1 NC_015500.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA topoisomerase, type IIA, subunit A or C-terminal; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A or C-terminal; SPTR: DNA gyrase subunit A; IMG reference gene:2504919763; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA topoisomerase 1079687 10579375 Trebr_0882 Treponema brennaborense DSM 12168 DNA topoisomerase YP_004439449.1 1077741 D 906968 CDS YP_004439450.1 332297528 10579376 1079725..1080654 1 NC_015500.1 KEGG: bwe:BcerKBAB4_5101 hypothetical protein; SPTR: Integral membrane protein; IMG reference gene:2504919764; PFAM: Protein of unknown function (DUF975); hypothetical protein 1080654 10579376 Trebr_0883 Treponema brennaborense DSM 12168 hypothetical protein YP_004439450.1 1079725 D 906968 CDS YP_004439451.1 332297529 10579377 1080658..1081287 1 NC_015500.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: tde:TDE1321 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: uncharacterized protein; IMG reference gene:2504919765; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family; hypothetical protein 1081287 10579377 Trebr_0884 Treponema brennaborense DSM 12168 hypothetical protein YP_004439451.1 1080658 D 906968 CDS YP_004439452.1 332297530 10579378 complement(1081244..1082182) 1 NC_015500.1 KEGG: ssm:Spirs_0536 type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; IMG reference gene:2504919766; hypothetical protein 1082182 10579378 Trebr_0885 Treponema brennaborense DSM 12168 hypothetical protein YP_004439452.1 1081244 R 906968 CDS YP_004439453.1 332297531 10579379 complement(1082316..1083770) 1 NC_015500.1 COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase; InterPro IPR004522:IPR004365:IPR004364; KEGG: tde:TDE0980 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb; IMG reference gene:2504919767; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; Asparaginyl-tRNA synthetase 1083770 10579379 Trebr_0886 Treponema brennaborense DSM 12168 Asparaginyl-tRNA synthetase YP_004439453.1 1082316 R 906968 CDS YP_004439454.1 332297532 10579380 1083920..1085113 1 NC_015500.1 KEGG: dma:DMR_05530 hypothetical membrane protein; SPTR: uncharacterized protein; IMG reference gene:2504919768; PFAM: Acyltransferase family; hypothetical protein 1085113 10579380 Trebr_0887 Treponema brennaborense DSM 12168 hypothetical protein YP_004439454.1 1083920 D 906968 CDS YP_004439455.1 332297533 10579381 1085377..1085844 1 NC_015500.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: ssm:Spirs_4222 protein of unknown function UPF0066; PFAM: Uncharacterised protein family UPF0066; SPTR: uncharacterized protein; IMG reference gene:2504919769; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: methyltransferase, YaeB/AF_0241 family; hypothetical protein 1085844 10579381 Trebr_0888 Treponema brennaborense DSM 12168 hypothetical protein YP_004439455.1 1085377 D 906968 CDS YP_004439456.1 332297534 10579382 complement(1085869..1086894) 1 NC_015500.1 InterPro IPR018060; KEGG: ssm:Spirs_4223 transcriptional regulator, AraC family; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504919770; PFAM: Bacterial transcription activator, effector binding domain; AraC family transcriptional regulator 1086894 10579382 Trebr_0889 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439456.1 1085869 R 906968 CDS YP_004439457.1 332297535 10579383 1086972..1088378 1 NC_015500.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR004780:IPR013822:IPR000897:IPR004125:IPR 003593; KEGG: tde:TDE2089 signal recognition particle protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; SMART: ATPase, AAA+ type, core; SPTR: Signal recognition particle protein; TIGRFAM: Signal recognition particle, SRP; IMG reference gene:2504919771; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein; signal recognition particle protein 1088378 10579383 Trebr_0890 Treponema brennaborense DSM 12168 signal recognition particle protein YP_004439457.1 1086972 D 906968 CDS YP_004439458.1 332297536 10579384 1088685..1091450 1 NC_015500.1 COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR004869; KEGG: ssm:Spirs_3722 hypothetical protein; PFAM: MMPL; SPTR: uncharacterized protein; IMG reference gene:2504919772; PFAM: MMPL family; MMPL domain protein 1091450 10579384 Trebr_0891 Treponema brennaborense DSM 12168 MMPL domain protein YP_004439458.1 1088685 D 906968 CDS YP_004439459.1 332297537 10579385 1091489..1092259 1 NC_015500.1 KEGG: ssm:Spirs_3728 sigma E regulatory protein, MucB/RseB; SPTR: sigma E regulatory protein, MucB/RseB; IMG reference gene:2504919773; PFAM: Protein of unknown function (DUF1329); sigma E regulatory protein MucB/RseB 1092259 10579385 Trebr_0892 Treponema brennaborense DSM 12168 sigma E regulatory protein MucB/RseB YP_004439459.1 1091489 D 906968 CDS YP_004439460.1 332297538 10579386 1092286..1093845 1 NC_015500.1 KEGG: ssm:Spirs_3729 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919774; hypothetical protein 1093845 10579386 Trebr_0893 Treponema brennaborense DSM 12168 hypothetical protein YP_004439460.1 1092286 D 906968 CDS YP_004439461.1 332297539 10579387 complement(1093904..1095058) 1 NC_015500.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: bpb:bpr_I1756 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504919775; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 1095058 10579387 Trebr_0894 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004439461.1 1093904 R 906968 CDS YP_004439462.1 332297540 10579388 1095261..1096982 1 NC_015500.1 KEGG: tde:TDE2784 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919776; hypothetical protein 1096982 10579388 Trebr_0895 Treponema brennaborense DSM 12168 hypothetical protein YP_004439462.1 1095261 D 906968 CDS YP_004439463.1 332297541 10579389 1096988..1098028 1 NC_015500.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: ssm:Spirs_1800 protein of unknown function DUF152; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: uncharacterized protein; IMG reference gene:2504919777; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; multi-copper polyphenol oxidoreductase, laccase 1098028 10579389 Trebr_0896 Treponema brennaborense DSM 12168 multi-copper polyphenol oxidoreductase, laccase YP_004439463.1 1096988 D 906968 CDS YP_004439464.1 332297542 10579390 complement(1098126..1099262) 1 NC_015500.1 COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: cpy:Cphy_0203 glycosy hydrolase family protein; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88; IMG reference gene:2504919778; PFAM: Glycosyl Hydrolase Family 88; glycosyl hydrolase family protein 1099262 10579390 Trebr_0897 Treponema brennaborense DSM 12168 glycosyl hydrolase family protein YP_004439464.1 1098126 R 906968 CDS YP_004439465.1 332297543 10579391 1099369..1101165 1 NC_015500.1 COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: tde:TDE0971 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; Arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; IMG reference gene:2504919779; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; arginyl-tRNA synthetase 1101165 10579391 Trebr_0898 Treponema brennaborense DSM 12168 arginyl-tRNA synthetase YP_004439465.1 1099369 D 906968 CDS YP_004439466.1 332297544 10579392 complement(1101169..1101786) 1 NC_015500.1 IMG reference gene:2504919780; hypothetical protein 1101786 10579392 Trebr_0899 Treponema brennaborense DSM 12168 hypothetical protein YP_004439466.1 1101169 R 906968 CDS YP_004439467.1 332297545 10579393 complement(1101927..1103723) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: azl:AZL_007150 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919781; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1103723 10579393 Trebr_0900 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439467.1 1101927 R 906968 CDS YP_004439468.1 332297546 10579394 complement(1103886..1104320) 1 NC_015500.1 KEGG: dhd:Dhaf_2679 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919782; hypothetical protein 1104320 10579394 Trebr_0901 Treponema brennaborense DSM 12168 hypothetical protein YP_004439468.1 1103886 R 906968 CDS YP_004439469.1 332297547 10579395 1104500..1104745 1 NC_015500.1 COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: tde:TDE0881 ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16; IMG reference gene:2504919783; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; 30S ribosomal protein S16 1104745 10579395 Trebr_0902 Treponema brennaborense DSM 12168 30S ribosomal protein S16 YP_004439469.1 1104500 D 906968 CDS YP_004439470.1 332297548 10579396 1104765..1104998 1 NC_015500.1 COGs: COG1837 RNA-binding protein (contains KH domain); HAMAP: Uncharacterised protein family UPF0109, bacterial; InterPro IPR020627; KEGG: tde:TDE0882 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919784; hypothetical protein 1104998 10579396 Trebr_0903 Treponema brennaborense DSM 12168 hypothetical protein YP_004439470.1 1104765 D 906968 CDS YP_004439471.1 332297549 10579397 1104998..1105585 1 NC_015500.1 COGs: COG0806 RimM protein required for 16S rRNA processing; HAMAP: 16S rRNA processing protein RimM; InterPro IPR011961:IPR002676:IPR007903; KEGG: sta:STHERM_c10550 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel; SPTR: 16S rRNA processing protein RimM; TIGRFAM: 16S rRNA processing protein RimM; IMG reference gene:2504919785; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM; Ribosome maturation factor rimM 1105585 10579397 Trebr_0904 Treponema brennaborense DSM 12168 Ribosome maturation factor rimM YP_004439471.1 1104998 D 906968 CDS YP_004439472.1 332297550 10579398 1105592..1106386 1 NC_015500.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; HAMAP: tRNA (guanine-N1-)-methyltransferase, bacteria; InterPro IPR002649:IPR016009; KEGG: tde:TDE0884 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1-)-methyltransferase, bacteria; IMG reference gene:2504919786; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; tRNA (guanine-N(1)-)-methyltransferase 1106386 10579398 Trebr_0905 Treponema brennaborense DSM 12168 tRNA (guanine-N(1)-)-methyltransferase YP_004439472.1 1105592 D 906968 CDS YP_004439473.1 332297551 10579399 1106399..1106770 1 NC_015500.1 COGs: COG0335 Ribosomal protein L19; HAMAP: Ribosomal protein L19; InterPro IPR001857; KEGG: tde:TDE0885 50S ribosomal protein L19; PFAM: Ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: Ribosomal protein L19; IMG reference gene:2504919787; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type; 50S ribosomal protein L19 1106770 10579399 Trebr_0906 Treponema brennaborense DSM 12168 50S ribosomal protein L19 YP_004439473.1 1106399 D 906968 CDS YP_004439474.1 332297552 10579400 1106797..1107942 1 NC_015500.1 KEGG: tde:TDE0886 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919788; hypothetical protein 1107942 10579400 Trebr_0907 Treponema brennaborense DSM 12168 hypothetical protein YP_004439474.1 1106797 D 906968 CDS YP_004439475.1 332297553 10579401 1107945..1108241 1 NC_015500.1 COGs: COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; KEGG: mta:Moth_1003 flagellar biosynthesis; SPTR: Flagellar biosynthesis; IMG reference gene:2504919789; PFAM: FlhB HrpN YscU SpaS Family; FlhB domain-containing protein 1108241 10579401 Trebr_0908 Treponema brennaborense DSM 12168 FlhB domain-containing protein YP_004439475.1 1107945 D 906968 CDS YP_004439476.1 332297554 10579402 1108222..1108485 1 NC_015500.1 KEGG: tde:TDE2302 HD domain-containing protein; SPTR: HD domain protein; IMG reference gene:2504919790; HD domain-containing protein 1108485 10579402 Trebr_0909 Treponema brennaborense DSM 12168 HD domain-containing protein YP_004439476.1 1108222 D 906968 CDS YP_004439477.1 332297555 10579403 1108463..1108873 1 NC_015500.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: tpp:TPASS_0913 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: HD domain protein; TIGRFAM: Uncharacterised protein family UPF0102; IMG reference gene:2504919791; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; hypothetical protein 1108873 10579403 Trebr_0910 Treponema brennaborense DSM 12168 hypothetical protein YP_004439477.1 1108463 D 906968 CDS YP_004439478.1 332297556 10579404 1108870..1109037 1 NC_015500.1 IMG reference gene:2504919792; hypothetical protein 1109037 10579404 Trebr_0911 Treponema brennaborense DSM 12168 hypothetical protein YP_004439478.1 1108870 D 906968 CDS YP_004439479.1 332297557 10579405 1109040..1109570 1 NC_015500.1 KEGG: tde:TDE2305 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919793; hypothetical protein 1109570 10579405 Trebr_0912 Treponema brennaborense DSM 12168 hypothetical protein YP_004439479.1 1109040 D 906968 CDS YP_004439480.1 332297558 10579407 complement(1109833..1110378) 1 NC_015500.1 IMG reference gene:2504919795; hypothetical protein 1110378 10579407 Trebr_0913 Treponema brennaborense DSM 12168 hypothetical protein YP_004439480.1 1109833 R 906968 CDS YP_004439481.1 332297559 10579408 1110415..1112214 1 NC_015500.1 KEGG: ssm:Spirs_2772 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919796; hypothetical protein 1112214 10579408 Trebr_0914 Treponema brennaborense DSM 12168 hypothetical protein YP_004439481.1 1110415 D 906968 CDS YP_004439482.1 332297560 10579409 complement(1112204..1112785) 1 NC_015500.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: tde:TDE1229 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919797; PFAM: Metallo-beta-lactamase superfamily; hypothetical protein 1112785 10579409 Trebr_0915 Treponema brennaborense DSM 12168 hypothetical protein YP_004439482.1 1112204 R 906968 CDS YP_004439483.1 332297561 10579410 complement(1112782..1113411) 1 NC_015500.1 KEGG: ssm:Spirs_2468 pentapeptide repeat protein; SPTR: Pentapeptide repeat protein; IMG reference gene:2504919798; pentapeptide repeat-containing protein 1113411 10579410 Trebr_0916 Treponema brennaborense DSM 12168 pentapeptide repeat-containing protein YP_004439483.1 1112782 R 906968 CDS YP_004439484.1 332297562 10579411 1113465..1113746 1 NC_015500.1 KEGG: sta:STHERM_c17060 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919799; hypothetical protein 1113746 10579411 Trebr_0917 Treponema brennaborense DSM 12168 hypothetical protein YP_004439484.1 1113465 D 906968 CDS YP_004439485.1 332297563 10579412 1113758..1114606 1 NC_015500.1 COGs: COG0796 Glutamate racemase; HAMAP: Glutamate racemase; InterPro IPR004391:IPR015942; KEGG: tde:TDE1448 glutamate racemase, PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: Glutamate racemase; IMG reference gene:2504919800; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase; Glutamate racemase 1114606 10579412 Trebr_0918 Treponema brennaborense DSM 12168 Glutamate racemase YP_004439485.1 1113758 D 906968 CDS YP_004439486.1 332297564 10579413 complement(1114665..1115681) 1 NC_015500.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR006674:IPR003607; KEGG: plm:Plim_0679 response regulator receiver; PFAM: Signal transduction response regulator, receiver region; Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Signal transduction response regulator, receiver region; Metal-dependent phosphohydrolase, HD region; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; IMG reference gene:2504919801; PFAM: HD domain; Response regulator receiver domain; response regulator receiver modulated metal dependent phosphohydrolase 1115681 10579413 Trebr_0919 Treponema brennaborense DSM 12168 response regulator receiver modulated metal dependent phosphohydrolase YP_004439486.1 1114665 R 906968 CDS YP_004439487.1 332297565 10579414 complement(1115715..1116914) 1 NC_015500.1 COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004790:IPR001804; KEGG: afn:Acfer_0606 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, eukaryotic; IMG reference gene:2504919802; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; isocitrate dehydrogenase 1116914 10579414 Trebr_0920 Treponema brennaborense DSM 12168 isocitrate dehydrogenase YP_004439487.1 1115715 R 906968 CDS YP_004439488.1 332297566 10579415 1117005..1117781 1 NC_015500.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: ccb:Clocel_1800 hypothetical protein; PFAM: Protein of unknown function DUF1212; SPTR: uncharacterized protein; IMG reference gene:2504919803; PFAM: Protein of unknown function (DUF1212); hypothetical protein 1117781 10579415 Trebr_0921 Treponema brennaborense DSM 12168 hypothetical protein YP_004439488.1 1117005 D 906968 CDS YP_004439489.1 332297567 10579416 1117768..1118223 1 NC_015500.1 COGs: COG3610 conserved hypothetical protein; KEGG: cst:CLOST_1298 membrane spanning protein; SPTR: Membrane spanning protein; IMG reference gene:2504919804; membrane spanning protein 1118223 10579416 Trebr_0922 Treponema brennaborense DSM 12168 membrane spanning protein YP_004439489.1 1117768 D 906968 CDS YP_004439490.1 332297568 10579417 1118496..1119359 1 NC_015500.1 InterPro IPR003856; KEGG: lipopolysaccharide biosynthesis protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: Lipopolysaccharide biosynthesis protein; IMG reference gene:2504919805; PFAM: Chain length determinant protein; lipopolysaccharide biosynthesis protein 1119359 10579417 Trebr_0923 Treponema brennaborense DSM 12168 lipopolysaccharide biosynthesis protein YP_004439490.1 1118496 D 906968 CDS YP_004439491.1 332297569 10579418 1119394..1120860 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: ssm:Spirs_0715 protein of unknown function DUF214; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: uncharacterized protein; IMG reference gene:2504919806; PFAM: Predicted permease; hypothetical protein 1120860 10579418 Trebr_0924 Treponema brennaborense DSM 12168 hypothetical protein YP_004439491.1 1119394 D 906968 CDS YP_004439492.1 332297570 10579419 1120862..1122121 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: ssm:Spirs_0716 protein of unknown function DUF214; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: uncharacterized protein; IMG reference gene:2504919807; PFAM: Predicted permease; hypothetical protein 1122121 10579419 Trebr_0925 Treponema brennaborense DSM 12168 hypothetical protein YP_004439492.1 1120862 D 906968 CDS YP_004439493.1 332297571 10579420 1122136..1122906 1 NC_015500.1 KEGG: ssm:Spirs_0717 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919808; hypothetical protein 1122906 10579420 Trebr_0926 Treponema brennaborense DSM 12168 hypothetical protein YP_004439493.1 1122136 D 906968 CDS YP_004439494.1 332297572 10579421 1122909..1124048 1 NC_015500.1 IMG reference gene:2504919809; hypothetical protein 1124048 10579421 Trebr_0927 Treponema brennaborense DSM 12168 hypothetical protein YP_004439494.1 1122909 D 906968 CDS YP_004439495.1 332297573 10579422 complement(1124050..1124748) 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE1852 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504919810; PFAM: ABC transporter; polyamine-transporting ATPase 1124748 10579422 Trebr_0928 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004439495.1 1124050 R 906968 CDS YP_004439496.1 332297574 10579423 1124927..1125955 1 NC_015500.1 InterPro IPR003856; KEGG: glo:Glov_1511 lipopolysaccharide biosynthesis protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: Chain length determinant protein; IMG reference gene:2504919811; PFAM: Chain length determinant protein; lipopolysaccharide biosynthesis protein 1125955 10579423 Trebr_0929 Treponema brennaborense DSM 12168 lipopolysaccharide biosynthesis protein YP_004439496.1 1124927 D 906968 CDS YP_004439497.1 332297575 10579424 1125960..1127549 1 NC_015500.1 InterPro IPR019554; KEGG: sta:STHERM_c15850 polysaccharide biosynthesis protein; PFAM: Soluble ligand binding domain; SPTR: polysaccharide export protein; IMG reference gene:2504919812; PFAM: SLBB domain; Soluble ligand binding domain-containing protein 1127549 10579424 Trebr_0930 Treponema brennaborense DSM 12168 Soluble ligand binding domain-containing protein YP_004439497.1 1125960 D 906968 CDS YP_004439498.1 332297576 10579425 1127699..1128937 1 NC_015500.1 COGs: COG0162 Tyrosyl-tRNA synthetase; HAMAP: Tyrosyl-tRNA synthetase; InterPro IPR002307:IPR002305; KEGG: tde:TDE0861 tyrosyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tyrosine--tRNA ligase; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial; IMG reference gene:2504919813; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 1128937 10579425 Trebr_0931 Treponema brennaborense DSM 12168 tyrosyl-tRNA synthetase YP_004439498.1 1127699 D 906968 CDS YP_004439499.1 332297577 10579426 1128954..1129790 1 NC_015500.1 KEGG: elm:ELI_3357 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919814; PFAM: Predicted membrane protein (DUF2238); hypothetical protein 1129790 10579426 Trebr_0932 Treponema brennaborense DSM 12168 hypothetical protein YP_004439499.1 1128954 D 906968 CDS YP_004439500.1 332297578 10579427 1130162..1130356 1 NC_015500.1 IMG reference gene:2504919815; hypothetical protein 1130356 10579427 Trebr_0933 Treponema brennaborense DSM 12168 hypothetical protein YP_004439500.1 1130162 D 906968 CDS YP_004439501.1 332297579 10579432 1135817..1137052 1 NC_015500.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR003607:IPR006674; KEGG: tde:TDE2659 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: Metal-dependent phosphohydrolase, HD region; GAF; SPTR: GAF domain/HD domain protein; IMG reference gene:2504919820; PFAM: HD domain; GAF domain; metal dependent phosphohydrolase with GAF sensor 1137052 10579432 Trebr_0934 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase with GAF sensor YP_004439501.1 1135817 D 906968 CDS YP_004439502.1 332297580 10579433 complement(1137049..1137516) 1 NC_015500.1 COGs: COG1671 conserved hypothetical protein; HAMAP: Protein of unknown function DUF188; InterPro IPR003791; KEGG: tde:TDE2151 hypothetical protein; PFAM: Protein of unknown function DUF188; SPTR: UPF0178 protein TDE_2151; IMG reference gene:2504919821; PFAM: Uncharacterized BCR, YaiI/YqxD family COG1671; hypothetical protein 1137516 10579433 Trebr_0935 Treponema brennaborense DSM 12168 hypothetical protein YP_004439502.1 1137049 R 906968 CDS YP_004439503.1 332297581 10579434 complement(1137520..1137822) 1 NC_015500.1 KEGG: tpp:TPASS_0846 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919822; PFAM: Cell division protein ZapA; hypothetical protein 1137822 10579434 Trebr_0936 Treponema brennaborense DSM 12168 hypothetical protein YP_004439503.1 1137520 R 906968 CDS YP_004439504.1 332297582 10579435 complement(1137866..1138360) 1 NC_015500.1 KEGG: sta:STHERM_c07780 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919823; hypothetical protein 1138360 10579435 Trebr_0937 Treponema brennaborense DSM 12168 hypothetical protein YP_004439504.1 1137866 R 906968 CDS YP_004439505.1 332297583 10579436 complement(1138364..1138723) 1 NC_015500.1 COGs: COG0292 Ribosomal protein L20; HAMAP: Ribosomal protein L20; InterPro IPR005813; KEGG: tde:TDE2154 50S ribosomal protein L20; PFAM: Ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: Ribosomal protein L20; IMG reference gene:2504919824; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20; 50S ribosomal protein L20 1138723 10579436 Trebr_0938 Treponema brennaborense DSM 12168 50S ribosomal protein L20 YP_004439505.1 1138364 R 906968 CDS YP_004439506.1 332297584 10579437 complement(1138744..1138944) 1 NC_015500.1 HAMAP: Ribosomal protein L35; InterPro IPR001706; KEGG: tde:TDE2155 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: Ribosomal protein L35; IMG reference gene:2504919825; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; 50S ribosomal protein L35 1138944 10579437 Trebr_0939 Treponema brennaborense DSM 12168 50S ribosomal protein L35 YP_004439506.1 1138744 R 906968 CDS YP_004439507.1 332297585 10579438 complement(1138958..1139479) 1 NC_015500.1 COGs: COG0290 Translation initiation factor 3 (IF-3); HAMAP: Translation initiation factor IF-3; InterPro IPR001288:IPR019814:IPR019815; KEGG: sta:STHERM_c07810 translation initiation factor IF-3; PFAM: Translation initiation factor 3, N-terminal; Translation initiation factor 3, C-terminal; SPTR: Translation initiation factor IF-3; TIGRFAM: Translation initiation factor 3; manually curated; IMG reference gene:2504919826; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3; Translation initiation factor IF-3 1139479 10579438 Trebr_0940 Treponema brennaborense DSM 12168 Translation initiation factor IF-3 YP_004439507.1 1138958 R 906968 CDS YP_004439508.1 332297586 10579439 1139694..1140386 1 NC_015500.1 IMG reference gene:2504919827; hypothetical protein 1140386 10579439 Trebr_0941 Treponema brennaborense DSM 12168 hypothetical protein YP_004439508.1 1139694 D 906968 CDS YP_004439509.1 332297587 10579440 complement(1140512..1141510) 1 NC_015500.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: tpp:TPASS_0662 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504919828; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; fructose-1,6-bisphosphate aldolase 1141510 10579440 Trebr_0942 Treponema brennaborense DSM 12168 fructose-1,6-bisphosphate aldolase YP_004439509.1 1140512 R 906968 CDS YP_004439510.1 332297588 10579441 1141683..1142408 1 NC_015500.1 InterPro IPR006714; KEGG: tde:TDE1408 flagellar filament outer layer protein FlaA, PFAM: Flagellar filament outer layer protein FlaA; SPTR: Outer membrane protein; IMG reference gene:2504919829; PFAM: Flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA 1142408 10579441 Trebr_0943 Treponema brennaborense DSM 12168 flagellar filament outer layer protein FlaA YP_004439510.1 1141683 D 906968 CDS YP_004439511.1 332297589 10579442 1142429..1143154 1 NC_015500.1 InterPro IPR006714; KEGG: tpp:TPASS_0664 flagellar filament outer layer protein; PFAM: Flagellar filament outer layer protein FlaA; SPTR: Flagellar filament outer layer protein; IMG reference gene:2504919830; PFAM: Flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA 1143154 10579442 Trebr_0944 Treponema brennaborense DSM 12168 flagellar filament outer layer protein FlaA YP_004439511.1 1142429 D 906968 CDS YP_004439512.1 332297590 10579443 complement(1143236..1143931) 1 NC_015500.1 KEGG: tpp:TPASS_0665 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919831; hypothetical protein 1143931 10579443 Trebr_0945 Treponema brennaborense DSM 12168 hypothetical protein YP_004439512.1 1143236 R 906968 CDS YP_004439513.1 332297591 10579444 1144078..1144521 1 NC_015500.1 COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR003444:IPR020603; KEGG: tde:TDE1197 cell division protein MraZ; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ; IMG reference gene:2504919832; PFAM: MraZ protein; TIGRFAM: mraZ protein; protein mraZ 1144521 10579444 Trebr_0946 Treponema brennaborense DSM 12168 protein mraZ YP_004439513.1 1144078 D 906968 CDS YP_004439514.1 332297592 10579445 1144534..1145526 1 NC_015500.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; HAMAP: S-adenosyl-L-methionine-dependent methyltransferase, MraW; InterPro IPR002903; KEGG: tde:TDE1198 S-adenosyl-methyltransferase MraW; PFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; IMG reference gene:2504919833; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW; Ribosomal RNA small subunit methyltransferase H 1145526 10579445 Trebr_0947 Treponema brennaborense DSM 12168 Ribosomal RNA small subunit methyltransferase H YP_004439514.1 1144534 D 906968 CDS YP_004439515.1 332297593 10579446 1145543..1145839 1 NC_015500.1 KEGG: tde:TDE1199 cell division protein FtsL, SPTR: Cell division protein FtsL, ; IMG reference gene:2504919834; PFAM: Septum formation initiator; TIGRFAM: cell division protein FtsL; cell division protein FtsL 1145839 10579446 Trebr_0948 Treponema brennaborense DSM 12168 cell division protein FtsL YP_004439515.1 1145543 D 906968 CDS YP_004439516.1 332297594 10579447 1145836..1147302 1 NC_015500.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863:IPR000713:IPR013221:IPR004101; KEGG: tde:TDE1200 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanyl ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-a lanineligase; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase; IMG reference gene:2504919835; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase 1147302 10579447 Trebr_0949 Treponema brennaborense DSM 12168 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase YP_004439516.1 1145836 D 906968 CDS YP_004439517.1 332297595 10579448 1147299..1148453 1 NC_015500.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; IMG reference gene:2504919836; PFAM: Cell cycle protein; cell cycle protein 1148453 10579448 Trebr_0950 Treponema brennaborense DSM 12168 cell cycle protein YP_004439517.1 1147299 D 906968 CDS YP_004439518.1 332297596 10579449 1148499..1149329 1 NC_015500.1 COGs: COG1589 Cell division septal protein; InterPro IPR013685; KEGG: tde:TDE1202 cell division protein FtsQ, PFAM: Polypeptide-transport-associated, FtsQ-type; SPTR: Cell division protein FtsQ, ; IMG reference gene:2504919837; PFAM: Cell division protein FtsQ; POTRA domain, FtsQ-type; polypeptide-transport-associated domain-containing protein FtsQ-type 1149329 10579449 Trebr_0951 Treponema brennaborense DSM 12168 polypeptide-transport-associated domain-containing protein FtsQ-type YP_004439518.1 1148499 D 906968 CDS YP_004439519.1 332297597 10579450 1149438..1150700 1 NC_015500.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR020823:IPR003494; KEGG: ssm:Spirs_1551 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; IMG reference gene:2504919838; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA; cell division protein FtsA 1150700 10579450 Trebr_0952 Treponema brennaborense DSM 12168 cell division protein FtsA YP_004439519.1 1149438 D 906968 CDS YP_004439520.1 332297598 10579451 1150814..1152133 1 NC_015500.1 COGs: COG0206 Cell division GTPase; InterPro IPR000158:IPR003008:IPR018316; KEGG: ssm:Spirs_1552 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal; IMG reference gene:2504919839; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ; cell division protein FtsZ 1152133 10579451 Trebr_0953 Treponema brennaborense DSM 12168 cell division protein FtsZ YP_004439520.1 1150814 D 906968 CDS YP_004439521.1 332297599 10579452 1152139..1153074 1 NC_015500.1 COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: ssm:Spirs_1553 tyrosine recombinase XerD; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase XerD; manually curated; IMG reference gene:2504919840; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; tyrosine recombinase xerC 1153074 10579452 Trebr_0954 Treponema brennaborense DSM 12168 tyrosine recombinase xerC YP_004439521.1 1152139 D 906968 CDS YP_004439522.1 332297600 10579453 1153148..1153879 1 NC_015500.1 InterPro IPR019734:IPR001440; KEGG: tde:TDE1206 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504919841; hypothetical protein 1153879 10579453 Trebr_0955 Treponema brennaborense DSM 12168 hypothetical protein YP_004439522.1 1153148 D 906968 CDS YP_004439523.1 332297601 10579454 1153869..1154858 1 NC_015500.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: tde:TDE1207 DNA processing protein DprA, PFAM: DNA recombination-mediator protein A; SPTR: Smf protein; TIGRFAM: DNA recombination-mediator protein A; IMG reference gene:2504919842; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA; DNA protecting protein DprA 1154858 10579454 Trebr_0956 Treponema brennaborense DSM 12168 DNA protecting protein DprA YP_004439523.1 1153869 D 906968 CDS YP_004439524.1 332297602 10579455 1154878..1157037 1 NC_015500.1 COGs: COG0550 Topoisomerase IA; InterProIPR005733:IPR006154:IPR003601:IPR003602:IPR 006171:IPR013497:IPR013498; KEGG: tde:TDE1208 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; DNA topoisomerase, type IA, zn finger; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; SPTR: DNA topoisomerase I; TIGRFAM: DNA topoisomerase I, bacterial-type; IMG reference gene:2504919843; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial; DNA topoisomerase I 1157037 10579455 Trebr_0957 Treponema brennaborense DSM 12168 DNA topoisomerase I YP_004439524.1 1154878 D 906968 CDS YP_004439525.1 332297603 10579456 1157041..1157967 1 NC_015500.1 COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: tde:TDE1209 phage integrase family site specific recombinase; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase xerC 2; IMG reference gene:2504919844; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; tyrosine recombinase xerC 1157967 10579456 Trebr_0958 Treponema brennaborense DSM 12168 tyrosine recombinase xerC YP_004439525.1 1157041 D 906968 CDS YP_004439526.1 332297604 10579457 1158051..1158590 1 NC_015500.1 COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; HAMAP: ATP-dependent protease hslV; InterPro IPR001353; KEGG: tde:TDE1210 ATP-dependent protease peptidase subunit; PFAM: Proteasome, subunit alpha/beta; SPTR: ATP-dependent protease subunit HslV; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit; IMG reference gene:2504919845; PFAM: Proteasome subunit; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit; ATP-dependent protease hslV 1158590 10579457 Trebr_0959 Treponema brennaborense DSM 12168 ATP-dependent protease hslV YP_004439526.1 1158051 D 906968 CDS YP_004439527.1 332297605 10579458 1158593..1160056 1 NC_015500.1 COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; HAMAP: ATP-dependent hsl protease ATP-binding subunit hslU; InterPro IPR004491:IPR003593:IPR013093; KEGG: tde:TDE1211 ATP-dependent protease ATP-binding subunit HslU; PFAM: ATPase associated with various cellular activities, AAA-2; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease ATPase subunit HslU; TIGRFAM: Heat shock protein HslU; IMG reference gene:2504919846; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; AAA domain (dynein-related subfamily); TIGRFAM: ATP-dependent protease HslVU, ATPase subunit; ATP-dependent hsl protease ATP-binding subunit hslU 1160056 10579458 Trebr_0960 Treponema brennaborense DSM 12168 ATP-dependent hsl protease ATP-binding subunit hslU YP_004439527.1 1158593 D 906968 CDS YP_004439528.1 332297606 10579459 1160299..1160715 1 NC_015500.1 COGs: COG1815 Flagellar basal body protein; InterPro IPR006300; KEGG: tde:TDE1212 flagellar basal-body rod protein FlgB; SPTR: Flagellar basal-body rod protein FlgB; TIGRFAM: Flagellar basal-body rod protein FlgB; IMG reference gene:2504919847; TIGRFAM: flagellar basal-body rod protein FlgB; flagellar basal-body rod protein FlgB 1160715 10579459 Trebr_0961 Treponema brennaborense DSM 12168 flagellar basal-body rod protein FlgB YP_004439528.1 1160299 D 906968 CDS YP_004439529.1 332297607 10579460 1160831..1161286 1 NC_015500.1 COGs: COG1558 Flagellar basal body rod protein; InterPro IPR006299:IPR001444:IPR010930; KEGG: sta:STHERM_c09080 hypothetical protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgC; TIGRFAM: Flagellar basal-body rod protein FlgC; IMG reference gene:2504919848; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; flagellar basal-body rod protein FlgC 1161286 10579460 Trebr_0962 Treponema brennaborense DSM 12168 flagellar basal-body rod protein FlgC YP_004439529.1 1160831 D 906968 CDS YP_004439530.1 332297608 10579461 1161361..1161696 1 NC_015500.1 COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: tpp:TPASS_0398 flagellar hook-basal body protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex protein fliE; TIGRFAM: Flagellar hook-basal body complex protein FliE; IMG reference gene:2504919849; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex subunit FliE 1161696 10579461 Trebr_0963 Treponema brennaborense DSM 12168 flagellar hook-basal body complex subunit FliE YP_004439530.1 1161361 D 906968 CDS YP_004439531.1 332297609 10579462 1161849..1163555 1 NC_015500.1 COGs: COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; InterPro IPR000067:IPR006182:IPR013556; KEGG: tpp:TPASS_0399 flagellar MS-ring protein; PFAM: Flagellar M-ring C-terminal; Secretory protein YscJ/FliF; SPTR: Flagellar M-ring protein FliF; TIGRFAM: Flagellar FliF M-ring protein; IMG reference gene:2504919850; PFAM: Flagellar M-ring protein C-terminal; Secretory protein of YscJ/FliF family; TIGRFAM: flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); flagellar M-ring protein FliF 1163555 10579462 Trebr_0964 Treponema brennaborense DSM 12168 flagellar M-ring protein FliF YP_004439531.1 1161849 D 906968 CDS YP_004439532.1 332297610 10579463 1163556..1164623 1 NC_015500.1 COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: tpp:TPASS_0400 flagellar motor switch protein G; PFAM: Flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG; TIGRFAM: Flagellar motor switch protein FliG; IMG reference gene:2504919851; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG; flagellar motor switch protein FliG 1164623 10579463 Trebr_0965 Treponema brennaborense DSM 12168 flagellar motor switch protein FliG YP_004439532.1 1163556 D 906968 CDS YP_004439533.1 332297611 10579464 1164627..1165562 1 NC_015500.1 COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: tde:TDE1217 flagellar assembly protein H; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein fliH, ; IMG reference gene:2504919852; PFAM: Flagellar assembly protein FliH; flagellar assembly protein FliH/type III secretion system HrpE 1165562 10579464 Trebr_0966 Treponema brennaborense DSM 12168 flagellar assembly protein FliH/type III secretion system HrpE YP_004439533.1 1164627 D 906968 CDS YP_004439534.1 332297612 10579465 1165581..1166939 1 NC_015500.1 COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR005714:IPR003593:IPR004100:IPR000194; KEGG: tde:TDE1218 flagellum-specific ATP synthase FliI; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; PRIAM: H(+)-transporting two-sector ATPase; SMART: ATPase, AAA+ type, core; SPTR: Flagellar protein export ATPase FliI; TIGRFAM: ATPase, type III secretion system, FliI/YscN; IMG reference gene:2504919853; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; FliI/YscN family ATPase 1166939 10579465 Trebr_0967 Treponema brennaborense DSM 12168 FliI/YscN family ATPase YP_004439534.1 1165581 D 906968 CDS YP_004439535.1 332297613 10579466 1166946..1167422 1 NC_015500.1 InterPro IPR012823; KEGG: tde:TDE1219 flagellar protein FliJ, SPTR: Flagellar protein FliJ, ; TIGRFAM: Flagellar export FliJ; IMG reference gene:2504919854; PFAM: Flagellar FliJ protein; TIGRFAM: flagellar export protein FliJ; flagellar export protein FliJ 1167422 10579466 Trebr_0968 Treponema brennaborense DSM 12168 flagellar export protein FliJ YP_004439535.1 1166946 D 906968 CDS YP_004439536.1 332297614 10579467 complement(1167419..1169071) 1 NC_015500.1 COGs: COG0572 Uridine kinase; InterPro IPR003593:IPR006083; KEGG: tde:TDE2289 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SMART: ATPase, AAA+ type, core; SPTR: Phosphoribulokinase/uridine kinase family protein; IMG reference gene:2504919855; PFAM: Phosphoribulokinase / Uridine kinase family; phosphoribulokinase/uridine kinase 1169071 10579467 Trebr_0969 Treponema brennaborense DSM 12168 phosphoribulokinase/uridine kinase YP_004439536.1 1167419 R 906968 CDS YP_004439537.1 332297615 10579468 1169189..1170412 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mfa:Mfla_0790 1,2-diacylglycerol 3-glucosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: 1,2-diacylglycerol 3-glucosyltransferase; IMG reference gene:2504919856; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 1170412 10579468 Trebr_0970 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004439537.1 1169189 D 906968 CDS YP_004439538.1 332297616 10579469 complement(1170536..1171732) 1 NC_015500.1 COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; HAMAP: Thiamine biosynthesis protein; InterPro IPR003720:IPR004114:IPR020536; KEGG: tde:TDE2568 thiamine biosynthesis protein ThiI; PFAM: Thiamine biosynthesis protein, C-terminal; THUMP; SPTR: Probable tRNA sulfurtransferase; TIGRFAM: Thiamine biosynthesis protein; IMG reference gene:2504919857; PFAM: Thiamine biosynthesis protein (ThiI); THUMP domain; TIGRFAM: thiazole biosynthesis/tRNA modification protein ThiI; tRNA sulfurtransferase 1171732 10579469 Trebr_0971 Treponema brennaborense DSM 12168 tRNA sulfurtransferase YP_004439538.1 1170536 R 906968 CDS YP_004439539.1 332297617 10579470 1171894..1173855 1 NC_015500.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: sta:STHERM_c08540 hypothetical protein; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase., 4-coumarate--CoA ligase; SPTR: AMP-binding enzyme family protein; IMG reference gene:2504919858; PFAM: AMP-binding enzyme; 4-coumarate--CoA ligase 1173855 10579470 Trebr_0972 Treponema brennaborense DSM 12168 4-coumarate--CoA ligase YP_004439539.1 1171894 D 906968 CDS YP_004439540.1 332297618 10579471 1173888..1175048 1 NC_015500.1 KEGG: tde:TDE1946 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919859; hypothetical protein 1175048 10579471 Trebr_0973 Treponema brennaborense DSM 12168 hypothetical protein YP_004439540.1 1173888 D 906968 CDS YP_004439541.1 332297619 10579472 complement(1175035..1175427) 1 NC_015500.1 InterPro IPR006976; KEGG: fsu:Fisuc_0295 VanZ family protein; PFAM: VanZ like protein; SPTR: VanZ like protein; IMG reference gene:2504919860; PFAM: VanZ like family; VanZ family protein 1175427 10579472 Trebr_0974 Treponema brennaborense DSM 12168 VanZ family protein YP_004439541.1 1175035 R 906968 CDS YP_004439542.1 332297620 10579473 complement(1175411..1176448) 1 NC_015500.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: tde:TDE2670 glycosyl transferase, group 4 family protein; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase, group 4 family protein; IMG reference gene:2504919861; PFAM: Glycosyl transferase family 4; Glycosyl transferase, family 4, conserved region-containing protein 1176448 10579473 Trebr_0975 Treponema brennaborense DSM 12168 Glycosyl transferase, family 4, conserved region-containing protein YP_004439542.1 1175411 R 906968 CDS YP_004439543.1 332297621 10579474 1176648..1177016 1 NC_015500.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: cac:CA_C1469 iron-dependent transcription repressor; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: uncharacterized protein; IMG reference gene:2504919862; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; DtxR family iron (metal) dependent repressor 1177016 10579474 Trebr_0976 Treponema brennaborense DSM 12168 DtxR family iron (metal) dependent repressor YP_004439543.1 1176648 D 906968 CDS YP_004439544.1 332297622 10579475 1177043..1177675 1 NC_015500.1 COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cvi:CV_1455 multiple antibiotic resistance protein MarC; PFAM: Multiple antibiotic resistance (MarC)-related; SPTR: membrane protein; TIGRFAM: Multiple antibiotic resistance (MarC)-related; IMG reference gene:2504919863; PFAM: MarC family integral membrane protein; TIGRFAM: membrane protein, MarC family; multiple antibiotic resistance (MarC)-like protein 1177675 10579475 Trebr_0977 Treponema brennaborense DSM 12168 multiple antibiotic resistance (MarC)-like protein YP_004439544.1 1177043 D 906968 CDS YP_004439545.1 332297623 10579476 1177675..1179114 1 NC_015500.1 COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR009049:IPR000362; KEGG: hmo:HM1_1460 argininosuccinate lyase; PFAM: Fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504919864; PFAM: Lyase; TIGRFAM: argininosuccinate lyase; argininosuccinate lyase 1179114 10579476 Trebr_0978 Treponema brennaborense DSM 12168 argininosuccinate lyase YP_004439545.1 1177675 D 906968 CDS YP_004439546.1 332297624 10579477 1179380..1180189 1 NC_015500.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: tjr:TherJR_0419 extracellular solute-binding protein family 3; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; SPTR: Extracellular solute-binding protein family 3; IMG reference gene:2504919865; PFAM: Bacterial extracellular solute-binding proteins, family 3; ABC transporter substrate-binding protein 1180189 10579477 Trebr_0979 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004439546.1 1179380 D 906968 CDS YP_004439547.1 332297625 10579478 1180208..1180843 1 NC_015500.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: cce:Ccel_0886 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; IMG reference gene:2504919866; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 1180843 10579478 Trebr_0980 Treponema brennaborense DSM 12168 polar amino acid ABC transporter inner membrane subunit YP_004439547.1 1180208 D 906968 CDS YP_004439548.1 332297626 10579479 1180858..1181604 1 NC_015500.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: eel:EUBELI_01396 polar amino acid transport system ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid ABC transporter ATP-binding protein, PAAT family (TC 3.A.1.3.-); IMG reference gene:2504919867; PFAM: ABC transporter; Phosphonate-transporting ATPase 1181604 10579479 Trebr_0981 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439548.1 1180858 D 906968 CDS YP_004439549.1 332297627 10579480 1181710..1182669 1 NC_015500.1 COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: sta:STHERM_c09740 PhoH-like protein; PFAM: PhoH-like protein; SPTR: PhoH family protein; manually curated; IMG reference gene:2504919868; PFAM: PhoH-like protein; PhoH family protein 1182669 10579480 Trebr_0982 Treponema brennaborense DSM 12168 PhoH family protein YP_004439549.1 1181710 D 906968 CDS YP_004439550.1 332297628 10579481 1182641..1184347 1 NC_015500.1 COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR006675:IPR003607:IPR011621:IPR006674; KEGG: tde:TDE1241 HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Metal-dependent phosphohydrolase, 7TM intracellular region; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: HD domain protein; TIGRFAM: HDIG; IMG reference gene:2504919869; PFAM: HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG; 7TM receptor with intracellular metal dependent phosphohydrolase 1184347 10579481 Trebr_0983 Treponema brennaborense DSM 12168 7TM receptor with intracellular metal dependent phosphohydrolase YP_004439550.1 1182641 D 906968 CDS YP_004439551.1 332297629 10579482 1184328..1184816 1 NC_015500.1 COGs: COG0319 metal-dependent hydrolase; HAMAP: Uncharacterised protein family UPF0054; InterPro IPR002036; KEGG: tde:TDE1242 metalloprotease; PFAM: Uncharacterised protein family UPF0054; SPTR: Probable rRNA maturation factor; TIGRFAM: Uncharacterised protein family UPF0054; IMG reference gene:2504919870; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; metalloprotease ybeY 1184816 10579482 Trebr_0984 Treponema brennaborense DSM 12168 metalloprotease ybeY YP_004439551.1 1184328 D 906968 CDS YP_004439552.1 332297630 10579483 1184830..1185621 1 NC_015500.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: tde:TDE1243 hemolysin C; PFAM: Transporter-associated region; Cystathionine beta-synthase, core; SPTR: Hemolysin C; IMG reference gene:2504919871; PFAM: CBS domain; Transporter associated domain; transporter-associated protein 1185621 10579483 Trebr_0985 Treponema brennaborense DSM 12168 transporter-associated protein YP_004439552.1 1184830 D 906968 CDS YP_004439553.1 332297631 10579484 1185618..1187738 1 NC_015500.1 InterPro IPR019734:IPR001440; KEGG: tde:TDE1244 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504919872; hypothetical protein 1187738 10579484 Trebr_0986 Treponema brennaborense DSM 12168 hypothetical protein YP_004439553.1 1185618 D 906968 CDS YP_004439554.1 332297632 10579485 complement(1187771..1188673) 1 NC_015500.1 KEGG: tde:TDE1245 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919873; hypothetical protein 1188673 10579485 Trebr_0987 Treponema brennaborense DSM 12168 hypothetical protein YP_004439554.1 1187771 R 906968 CDS YP_004439555.1 332297633 10579486 1188751..1189038 1 NC_015500.1 KEGG: tde:TDE2047 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919874; hypothetical protein 1189038 10579486 Trebr_0988 Treponema brennaborense DSM 12168 hypothetical protein YP_004439555.1 1188751 D 906968 CDS YP_004439556.1 332297634 10579487 join(1189075..1189143,1189145..1190212) 1 NC_015500.1 KEGG: bpm:BURPS1710b_3602 hypothetical protein; SPTR: Peptide chain release factor 2; IMG reference gene:2504919875; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2; Peptide chain release factor 2 1190212 10579487 Trebr_0989 Treponema brennaborense DSM 12168 Peptide chain release factor 2 YP_004439556.1 1189075 D 906968 CDS YP_004439557.1 332297635 10579488 1190209..1191825 1 NC_015500.1 KEGG: tde:TDE2044 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504919876; hypothetical protein 1191825 10579488 Trebr_0990 Treponema brennaborense DSM 12168 hypothetical protein YP_004439557.1 1190209 D 906968 CDS YP_004439558.1 332297636 10579489 1191827..1192705 1 NC_015500.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR004390:IPR003593:IPR013822:IPR000897; KEGG: tde:TDE2043 signal recognition particle-docking protein FtsY; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; SMART: ATPase, AAA+ type, core; SPTR: Signal recognition particle-docking protein FtsY; TIGRFAM: Cell division transporter substrate-binding protein FtsY; IMG reference gene:2504919877; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: signal recognition particle-docking protein FtsY; signal recognition particle-docking protein FtsY 1192705 10579489 Trebr_0991 Treponema brennaborense DSM 12168 signal recognition particle-docking protein FtsY YP_004439558.1 1191827 D 906968 CDS YP_004439559.1 332297637 10579490 1192705..1193499 1 NC_015500.1 IMG reference gene:2504919878; hypothetical protein 1193499 10579490 Trebr_0992 Treponema brennaborense DSM 12168 hypothetical protein YP_004439559.1 1192705 D 906968 CDS YP_004439560.1 332297638 10579491 1193496..1194776 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tde:TDE2041 lipoprotein releasing system, permease protein, PFAM: Protein of unknown function DUF214, permase predicted; SPTR: lipoprotein releasing system, permease protein; IMG reference gene:2504919879; PFAM: Predicted permease; hypothetical protein 1194776 10579491 Trebr_0993 Treponema brennaborense DSM 12168 hypothetical protein YP_004439560.1 1193496 D 906968 CDS YP_004439561.1 332297639 10579492 1194769..1195488 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE2040 lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Lipoprotein-releasing system ATP-binding protein LolD; IMG reference gene:2504919880; PFAM: ABC transporter; Phosphonate-transporting ATPase 1195488 10579492 Trebr_0994 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439561.1 1194769 D 906968 CDS YP_004439562.1 332297640 10579493 1195485..1196819 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tde:TDE2039 lipoprotein releasing system, permease protein, PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Lipoprotein releasing system, permease protein, ; IMG reference gene:2504919881; PFAM: Predicted permease; hypothetical protein 1196819 10579493 Trebr_0995 Treponema brennaborense DSM 12168 hypothetical protein YP_004439562.1 1195485 D 906968 CDS YP_004439563.1 332297641 10579494 1196822..1197367 1 NC_015500.1 COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: ssm:Spirs_1926 UvrB/UvrC protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; IMG reference gene:2504919882; PFAM: UvrB/uvrC motif; UvrB/UvrC protein 1197367 10579494 Trebr_0996 Treponema brennaborense DSM 12168 UvrB/UvrC protein YP_004439563.1 1196822 D 906968 CDS YP_004439564.1 332297642 10579495 1197364..1198512 1 NC_015500.1 COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: tde:TDE2037 ATP:guanido phosphotransferase domain-containing protein; PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase domain protein; IMG reference gene:2504919883; PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain; ATP:guanido phosphotransferase 1198512 10579495 Trebr_0997 Treponema brennaborense DSM 12168 ATP:guanido phosphotransferase YP_004439564.1 1197364 D 906968 CDS YP_004439565.1 332297643 10579496 1198549..1201131 1 NC_015500.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489; KEGG: ssm:Spirs_1928 ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATPase AAA-2 domain protein; IMG reference gene:2504919884; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; ATPase AAA-2 domain-containing protein 1201131 10579496 Trebr_0998 Treponema brennaborense DSM 12168 ATPase AAA-2 domain-containing protein YP_004439565.1 1198549 D 906968 CDS YP_004439566.1 332297644 10579498 complement(1204501..1205544) 1 NC_015500.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143:IPR000089; KEGG: ssm:Spirs_0899 efflux transporter, RND family, MFP subunit; PFAM: Biotin/lipoyl attachment; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504919886; PFAM: Biotin-requiring enzyme; TIGRFAM: RND family efflux transporter, MFP subunit; RND family efflux transporter MFP subunit 1205544 10579498 Trebr_1000 Treponema brennaborense DSM 12168 RND family efflux transporter MFP subunit YP_004439566.1 1204501 R 906968 CDS YP_004439567.1 332297645 10579499 complement(1205557..1206870) 1 NC_015500.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ssm:Spirs_0898 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; IMG reference gene:2504919887; PFAM: Outer membrane efflux protein; outer membrane efflux protein 1206870 10579499 Trebr_1001 Treponema brennaborense DSM 12168 outer membrane efflux protein YP_004439567.1 1205557 R 906968 CDS YP_004439568.1 332297646 10579500 1207036..1207752 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ssm:Spirs_3809 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2504919888; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; two component transcriptional regulator, winged helix family 1207752 10579500 Trebr_1002 Treponema brennaborense DSM 12168 two component transcriptional regulator, winged helix family YP_004439568.1 1207036 D 906968 CDS YP_004439569.1 332297647 10579501 1207749..1209170 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: ssm:Spirs_3808 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504919889; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 1209170 10579501 Trebr_1003 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004439569.1 1207749 D 906968 CDS YP_004439570.1 332297648 10579502 1209183..1209773 1 NC_015500.1 COGs: COG2249 NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: mmg:MTBMA_c07320 NADH dehydrogenase; PFAM: Flavodoxin-like fold; SPTR: Predicted NADH dehydrogenase; IMG reference gene:2504919890; PFAM: Flavodoxin-like fold; NAD(P)H dehydrogenase (quinone) 1209773 10579502 Trebr_1004 Treponema brennaborense DSM 12168 NAD(P)H dehydrogenase (quinone) YP_004439570.1 1209183 D 906968 CDS YP_004439571.1 332297649 10579503 1209909..1210448 1 NC_015500.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: cpy:Cphy_0524 rubrerythrin; PFAM: Rubrerythrin; SPTR: uncharacterized protein; tmRNA as predicted by Rfam (RF00023), score 121.50; IMG reference gene:2504919891; PFAM: Rubrerythrin; rubrerythrin 1210448 10579503 Trebr_R0022 Treponema brennaborense DSM 12168 rubrerythrin YP_004439571.1 1209909 D 906968 CDS YP_004439572.1 332297650 10579504 1211351..1212016 1 NC_015500.1 IMG reference gene:2504919892; hypothetical protein 1212016 10579504 Trebr_1006 Treponema brennaborense DSM 12168 hypothetical protein YP_004439572.1 1211351 D 906968 CDS YP_004439573.1 332297651 10579505 1212195..1213436 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504919893; PFAM: Transposase, Mutator family; transposase mutator type 1213436 10579505 Trebr_1007 Treponema brennaborense DSM 12168 transposase mutator type YP_004439573.1 1212195 D 906968 CDS YP_004439574.1 332297652 10579506 complement(1213964..1214560) 1 NC_015500.1 COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: ckr:CKR_0229 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: uncharacterized protein; IMG reference gene:2504919894; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1214560 10579506 Trebr_1008 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004439574.1 1213964 R 906968 CDS YP_004439575.1 332297653 10579507 1214697..1215221 1 NC_015500.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: ckr:CKR_0228 hypothetical protein; PFAM: Nitroreductase-like; SPTR: uncharacterized protein; IMG reference gene:2504919895; PFAM: Nitroreductase family; nitroreductase 1215221 10579507 Trebr_1009 Treponema brennaborense DSM 12168 nitroreductase YP_004439575.1 1214697 D 906968 CDS YP_004439576.1 332297654 10579508 1215252..1215674 1 NC_015500.1 COGs: COG1683 conserved hypothetical protein; InterPro IPR007553; KEGG: ckr:CKR_0227 hypothetical protein; PFAM: Protein of unknown function DUF523; SPTR: uncharacterized protein; IMG reference gene:2504919896; PFAM: Protein of unknown function (DUF523); hypothetical protein 1215674 10579508 Trebr_1010 Treponema brennaborense DSM 12168 hypothetical protein YP_004439576.1 1215252 D 906968 CDS YP_004439577.1 332297655 10579509 complement(1215757..1216653) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR003313:IPR000005; KEGG: ckr:CKR_0226 hypothetical protein; PFAM: Helix-turn-helix, AraC type; AraC protein, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; IMG reference gene:2504919897; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1216653 10579509 Trebr_1011 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439577.1 1215757 R 906968 CDS YP_004439578.1 332297656 10579510 1216765..1217925 1 NC_015500.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: ckr:CKR_0225 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: uncharacterized protein; IMG reference gene:2504919898; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 1217925 10579510 Trebr_1012 Treponema brennaborense DSM 12168 major facilitator superfamily protein YP_004439578.1 1216765 D 906968 CDS YP_004439579.1 332297657 10579511 1217939..1218772 1 NC_015500.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR004013; KEGG: ckr:CKR_0224 hypothetical protein; PFAM: PHP, C-terminal; SPTR: uncharacterized protein; TIGRFAM: Histidinol phosphate phosphatase, HisJ; IMG reference gene:2504919899; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; HisJ family histidinol phosphate phosphatase 1218772 10579511 Trebr_1013 Treponema brennaborense DSM 12168 HisJ family histidinol phosphate phosphatase YP_004439579.1 1217939 D 906968 CDS YP_004439580.1 332297658 10579512 1218826..1219689 1 NC_015500.1 InterPro IPR007530; KEGG: ckr:CKR_0223 hypothetical protein; PFAM: Streptomycin adenylyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504919900; PFAM: Streptomycin adenylyltransferase; adenylyltransferase 1219689 10579512 Trebr_1014 Treponema brennaborense DSM 12168 adenylyltransferase YP_004439580.1 1218826 D 906968 CDS YP_004439581.1 332297659 10579513 1219930..1220118 1 NC_015500.1 KEGG: ckl:CKL_0265 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919901; hypothetical protein 1220118 10579513 Trebr_1015 Treponema brennaborense DSM 12168 hypothetical protein YP_004439581.1 1219930 D 906968 CDS YP_004439582.1 332297660 10579514 1220606..1221025 1 NC_015500.1 InterPro IPR013249; KEGG: ckl:CKL_0264 hypothetical protein; PFAM: RNA polymerase sigma factor 70, region 4 type 2; SPTR: Conserved protein; IMG reference gene:2504919902; PFAM: Sigma-70, region 4; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; sigma-70 region 4 type 2 1221025 10579514 Trebr_1016 Treponema brennaborense DSM 12168 sigma-70 region 4 type 2 YP_004439582.1 1220606 D 906968 CDS YP_004439583.1 332297661 10579515 1221481..1221681 1 NC_015500.1 KEGG: ckl:CKL_0263 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919903; hypothetical protein 1221681 10579515 Trebr_1017 Treponema brennaborense DSM 12168 hypothetical protein YP_004439583.1 1221481 D 906968 CDS YP_004439584.1 332297662 10579516 1221823..1222086 1 NC_015500.1 KEGG: ckr:CKR_0221 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919904; hypothetical protein 1222086 10579516 Trebr_1018 Treponema brennaborense DSM 12168 hypothetical protein YP_004439584.1 1221823 D 906968 CDS YP_004439585.1 332297663 10579517 1222227..1223906 1 NC_015500.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119:IPR011109; KEGG: ckr:CKR_0220 hypothetical protein; PFAM: Recombinase; Resolvase, N-terminal; SPTR: uncharacterized protein; IMG reference gene:2504919905; PFAM: Recombinase; Resolvase, N terminal domain; recombinase 1223906 10579517 Trebr_1019 Treponema brennaborense DSM 12168 recombinase YP_004439585.1 1222227 D 906968 CDS YP_004439586.1 332297664 10579518 1224009..1224314 1 NC_015500.1 InterPro IPR003646:IPR013247; KEGG: afn:Acfer_1660 SH3 type 3 domain protein; PFAM: SH3, type 3; SMART: Bacterial SH3-like region; IMG reference gene:2504919906; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 1224314 10579518 Trebr_1020 Treponema brennaborense DSM 12168 SH3 type 3 domain-containing protein YP_004439586.1 1224009 D 906968 CDS YP_004439587.1 332297665 10579519 1224503..1225444 1 NC_015500.1 KEGG: ssm:Spirs_1767 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919907; hypothetical protein 1225444 10579519 Trebr_1021 Treponema brennaborense DSM 12168 hypothetical protein YP_004439587.1 1224503 D 906968 CDS YP_004439588.1 332297666 10579520 1225831..1226742 1 NC_015500.1 InterPro IPR010106; KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504919908; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 1226742 10579520 Trebr_1022 Treponema brennaborense DSM 12168 hypothetical protein YP_004439588.1 1225831 D 906968 CDS YP_004439589.1 332297667 10579522 1227567..1229054 1 NC_015500.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: tte:TTE1220 acetyl-CoA carboxylase alpha subunit; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Acetyl-CoA carboxylase alpha subunit; IMG reference gene:2504919910; PFAM: Carboxyl transferase domain; propionyl-CoA carboxylase 1229054 10579522 Trebr_1024 Treponema brennaborense DSM 12168 propionyl-CoA carboxylase YP_004439589.1 1227567 D 906968 CDS YP_004439590.1 332297668 10579523 1229172..1229636 1 NC_015500.1 KEGG: ssm:Spirs_1526 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919911; hypothetical protein 1229636 10579523 Trebr_1025 Treponema brennaborense DSM 12168 hypothetical protein YP_004439590.1 1229172 D 906968 CDS YP_004439591.1 332297669 10579524 complement(1229697..1230218) 1 NC_015500.1 InterPro IPR008254; KEGG: ere:EUBREC_3048 hypothetical protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: uncharacterized protein; IMG reference gene:2504919912; flavodoxin/nitric oxide synthase 1230218 10579524 Trebr_1026 Treponema brennaborense DSM 12168 flavodoxin/nitric oxide synthase YP_004439591.1 1229697 R 906968 CDS YP_004439592.1 332297670 10579525 complement(1230220..1232046) 1 NC_015500.1 IMG reference gene:2504919913; hypothetical protein 1232046 10579525 Trebr_1027 Treponema brennaborense DSM 12168 hypothetical protein YP_004439592.1 1230220 R 906968 CDS YP_004439593.1 332297671 10579526 complement(1232046..1233029) 1 NC_015500.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR010200:IPR001107; KEGG: ssm:Spirs_2891 HflC protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: HflC protein; TIGRFAM: HflC; IMG reference gene:2504919914; PFAM: SPFH domain / Band 7 family; TIGRFAM: HflC protein; HflC protein 1233029 10579526 Trebr_1028 Treponema brennaborense DSM 12168 HflC protein YP_004439593.1 1232046 R 906968 CDS YP_004439594.1 332297672 10579527 complement(1233029..1233994) 1 NC_015500.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR010201:IPR001107; KEGG: sta:STHERM_c16310 hypothetical protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: uncharacterized protein; TIGRFAM: HflK; IMG reference gene:2504919915; PFAM: SPFH domain / Band 7 family; TIGRFAM: HflK protein; HflK protein 1233994 10579527 Trebr_1029 Treponema brennaborense DSM 12168 HflK protein YP_004439594.1 1233029 R 906968 CDS YP_004439595.1 332297673 10579528 1234268..1234888 1 NC_015500.1 COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: ssm:Spirs_3496 transcriptional regulator, TetR family; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504919916; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1234888 10579528 Trebr_1030 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004439595.1 1234268 D 906968 CDS YP_004439596.1 332297674 10579529 1235039..1236874 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: elm:ELI_0926 ABC transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; IMG reference gene:2504919917; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 1236874 10579529 Trebr_1031 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004439596.1 1235039 D 906968 CDS YP_004439597.1 332297675 10579530 1236874..1238622 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR003439; KEGG: elm:ELI_0927 ABC transporter; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; IMG reference gene:2504919918; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 1238622 10579530 Trebr_1032 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004439597.1 1236874 D 906968 CDS YP_004439598.1 332297676 10579531 1238707..1240056 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: ele:Elen_0305 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: efflux protein, MATE family; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504919919; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 1240056 10579531 Trebr_1033 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004439598.1 1238707 D 906968 CDS YP_004439599.1 332297677 10579532 1240135..1240446 1 NC_015500.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: bpb:bpr_I2825 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator MerR family; IMG reference gene:2504919920; PFAM: MerR family regulatory protein; MerR family transcriptional regulator 1240446 10579532 Trebr_1034 Treponema brennaborense DSM 12168 MerR family transcriptional regulator YP_004439599.1 1240135 D 906968 CDS YP_004439600.1 332297678 10579533 complement(1240643..1242472) 1 NC_015500.1 InterPro IPR003961:IPR014867; KEGG: fbc:FB2170_12266 hypothetical protein; PFAM: Spore coat protein CotH; Fibronectin, type III; SPTR: CotH protein; IMG reference gene:2504919921; PFAM: CotH protein; spore coat protein CotH 1242472 10579533 Trebr_1035 Treponema brennaborense DSM 12168 spore coat protein CotH YP_004439600.1 1240643 R 906968 CDS YP_004439601.1 332297679 10579534 1242580..1242912 1 NC_015500.1 InterPro IPR001387; KEGG: ssm:Spirs_2166 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504919922; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 1242912 10579534 Trebr_1036 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439601.1 1242580 D 906968 CDS YP_004439602.1 332297680 10579536 1243642..1244403 1 NC_015500.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: mbn:Mboo_1036 amidohydrolase 2; PFAM: Amidohydrolase 2; PRIAM: o-pyrocatechuate decarboxylase; SPTR: Amidohydrolase family protein; IMG reference gene:2504919924; PFAM: Amidohydrolase; o-pyrocatechuate decarboxylase 1244403 10579536 Trebr_1038 Treponema brennaborense DSM 12168 o-pyrocatechuate decarboxylase YP_004439602.1 1243642 D 906968 CDS YP_004439603.1 332297681 10579537 1244664..1245752 1 NC_015500.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR010497:IPR000073; KEGG: bcl:ABC1387 epoxide hydrolase 1; PFAM: Epoxide hydrolase, N-terminal; Alpha/beta hydrolase fold-1; PRIAM: Microsomal epoxide hydrolase; SPTR: Epoxide hydrolase 1; IMG reference gene:2504919925; PFAM: alpha/beta hydrolase fold; Epoxide hydrolase N terminus; microsomal epoxide hydrolase 1245752 10579537 Trebr_1039 Treponema brennaborense DSM 12168 microsomal epoxide hydrolase YP_004439603.1 1244664 D 906968 CDS YP_004439604.1 332297682 10579538 1245820..1246383 1 NC_015500.1 COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cdf:CD0609 hypothetical protein; PFAM: Uncharacterised protein family UPF0157; SPTR: uncharacterized protein; IMG reference gene:2504919926; PFAM: Uncharacterised protein family (UPF0157); hypothetical protein 1246383 10579538 Trebr_1040 Treponema brennaborense DSM 12168 hypothetical protein YP_004439604.1 1245820 D 906968 CDS YP_004439605.1 332297683 10579539 1246410..1246949 1 NC_015500.1 COGs: COG3797 conserved hypothetical protein; InterPro IPR012545; KEGG: csh:Closa_3141 protein of unknown function DUF1697; PFAM: Protein of unknown function DUF1697; SPTR: uncharacterized protein; IMG reference gene:2504919927; PFAM: Protein of unknown function (DUF1697); hypothetical protein 1246949 10579539 Trebr_1041 Treponema brennaborense DSM 12168 hypothetical protein YP_004439605.1 1246410 D 906968 CDS YP_004439606.1 332297684 10579540 complement(1247114..1247713) 1 NC_015500.1 COGs: COG5523 integral membrane protein; InterPro IPR010380; KEGG: pjd:Pjdr2_0697 protein of unknown function DUF975; PFAM: Protein of unknown function DUF975; SPTR: uncharacterized protein; IMG reference gene:2504919928; PFAM: Protein of unknown function (DUF975); hypothetical protein 1247713 10579540 Trebr_1042 Treponema brennaborense DSM 12168 hypothetical protein YP_004439606.1 1247114 R 906968 CDS YP_004439607.1 332297685 10579541 1248454..1248777 1 NC_015500.1 InterPro IPR001387; KEGG: pjd:Pjdr2_4489 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504919929; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 1248777 10579541 Trebr_1043 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439607.1 1248454 D 906968 CDS YP_004439608.1 332297686 10579542 complement(1248908..1249534) 1 NC_015500.1 COGs: COG0693 intracellular protease/amidase; InterPro IPR002818; KEGG: mla:Mlab_0808 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: ThiJ/PfpI domain protein; IMG reference gene:2504919930; PFAM: DJ-1/PfpI family; ThiJ/PfpI domain-containing protein 1249534 10579542 Trebr_1044 Treponema brennaborense DSM 12168 ThiJ/PfpI domain-containing protein YP_004439608.1 1248908 R 906968 CDS YP_004439609.1 332297687 10579543 1249770..1250702 1 NC_015500.1 COGs: COG2378 transcriptional regulator protein; InterPro IPR013196; KEGG: elm:ELI_3261 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919931; PFAM: HTH domain; hypothetical protein 1250702 10579543 Trebr_1045 Treponema brennaborense DSM 12168 hypothetical protein YP_004439609.1 1249770 D 906968 CDS YP_004439610.1 332297688 10579545 1251451..1252764 1 NC_015500.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: swo:Swol_0027 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919933; PFAM: Archaeal ATPase; hypothetical protein 1252764 10579545 Trebr_1047 Treponema brennaborense DSM 12168 hypothetical protein YP_004439610.1 1251451 D 906968 CDS YP_004439611.1 332297689 10579546 1253400..1254050 1 NC_015500.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: eel:EUBELI_20156 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: Methyltransferase type 11; SPTR: uncharacterized protein; IMG reference gene:2504919934; PFAM: Methyltransferase domain; type 11 methyltransferase 1254050 10579546 Trebr_1048 Treponema brennaborense DSM 12168 type 11 methyltransferase YP_004439611.1 1253400 D 906968 CDS YP_004439612.1 332297690 10579547 1254308..1254916 1 NC_015500.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: csh:Closa_0967 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: uncharacterized protein; IMG reference gene:2504919935; PFAM: HD domain; metal dependent phosphohydrolase 1254916 10579547 Trebr_1049 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004439612.1 1254308 D 906968 CDS YP_004439613.1 332297691 10579548 1254989..1255402 1 NC_015500.1 COGs: COG2703 Hemerythrin; InterPro IPR012827:IPR012312; KEGG: ddf:DEFDS_1545 methyl-accepting chemotaxis protein; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Methyl-accepting chemotaxis protein; TIGRFAM: Haemerythrin-like, metal-binding; IMG reference gene:2504919936; PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein 1255402 10579548 Trebr_1050 Treponema brennaborense DSM 12168 hemerythrin-like metal-binding protein YP_004439613.1 1254989 D 906968 CDS YP_004439614.1 332297692 10579549 1255439..1256269 1 NC_015500.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: dhd:Dhaf_1985 nucleotide-binding protein; PFAM: ATPase-like, ParA/MinD; SPTR: Nucleotide-binding protein; IMG reference gene:2504919937; PFAM: ParA/MinD ATPase like; ParA/MinD-like ATPase 1256269 10579549 Trebr_1051 Treponema brennaborense DSM 12168 ParA/MinD-like ATPase YP_004439614.1 1255439 D 906968 CDS YP_004439615.1 332297693 10579550 1256266..1256796 1 NC_015500.1 InterPro IPR010181; KEGG: cce:Ccel_0233 C_GCAxxG_C_C family protein; PFAM: CGCAxxGCC motif; SPTR: C_GCAxxG_C_C family protein; TIGRFAM: CGCAxxGCC motif; IMG reference gene:2504919938; PFAM: redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein; C_GCAxxG_C_C family protein 1256796 10579550 Trebr_1052 Treponema brennaborense DSM 12168 C_GCAxxG_C_C family protein YP_004439615.1 1256266 D 906968 CDS YP_004439616.1 332297694 10579551 complement(1256863..1257900) 1 NC_015500.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269; KEGG: tde:TDE0122 dihydrouridine synthase, PFAM: tRNA-dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase; IMG reference gene:2504919939; PFAM: Dihydrouridine synthase (Dus); dihydrouridine synthase DuS 1257900 10579551 Trebr_1053 Treponema brennaborense DSM 12168 dihydrouridine synthase DuS YP_004439616.1 1256863 R 906968 CDS YP_004439617.1 332297695 10579552 1258003..1259460 1 NC_015500.1 COGs: COG0591 Na+/proline symporter; InterPro IPR019900:IPR001734; KEGG: pth:PTH_2848 Na+/panthothenate symporter; PFAM: Sodium/solute symporter; SPTR: Na+/panthothenate symporter; TIGRFAM: Sodium/solute symporter, subgroup; IMG reference gene:2504919940; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; SSS sodium solute transporter superfamily protein 1259460 10579552 Trebr_1054 Treponema brennaborense DSM 12168 SSS sodium solute transporter superfamily protein YP_004439617.1 1258003 D 906968 CDS YP_004439618.1 332297696 10579553 complement(1259535..1259873) 1 NC_015500.1 COGs: COG0073 EMAP domain; InterPro IPR002547; KEGG: aha:AHA_0208 hypothetical protein; PFAM: tRNA-binding region; SPTR: Methionyl-tRNA synthetase; IMG reference gene:2504919941; PFAM: tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; t-RNA-binding domain-containing protein 1259873 10579553 Trebr_1055 Treponema brennaborense DSM 12168 t-RNA-binding domain-containing protein YP_004439618.1 1259535 R 906968 CDS YP_004439619.1 332297697 10579554 1260220..1261509 1 NC_015500.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: amu:Amuc_2013 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; IMG reference gene:2504919942; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; O-acetylhomoserine/O-acetylserine sulfhydrylase 1261509 10579554 Trebr_1056 Treponema brennaborense DSM 12168 O-acetylhomoserine/O-acetylserine sulfhydrylase YP_004439619.1 1260220 D 906968 CDS YP_004439620.1 332297698 10579555 1261706..1262383 1 NC_015500.1 InterPro IPR005358; KEGG: tde:TDE0847 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: uncharacterized protein; IMG reference gene:2504919943; PFAM: Uncharacterised protein family (UPF0153); hypothetical protein 1262383 10579555 Trebr_1057 Treponema brennaborense DSM 12168 hypothetical protein YP_004439620.1 1261706 D 906968 CDS YP_004439621.1 332297699 10579556 1262397..1263269 1 NC_015500.1 COGs: COG0648 Endonuclease IV; HAMAP: Endodeoxyribonuclease IV; InterPro IPR001719:IPR012307; KEGG: dba:Dbac_2857 apurinic endonuclease Apn1; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: Endodeoxyribonuclease IV; SPTR: Probable endonuclease 4; TIGRFAM: Endodeoxyribonuclease IV; IMG reference gene:2504919944; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1); endonuclease 4 1263269 10579556 Trebr_1058 Treponema brennaborense DSM 12168 endonuclease 4 YP_004439621.1 1262397 D 906968 CDS YP_004439622.1 332297700 10579557 complement(1263340..1263789) 1 NC_015500.1 IMG reference gene:2504919945; hypothetical protein 1263789 10579557 Trebr_1059 Treponema brennaborense DSM 12168 hypothetical protein YP_004439622.1 1263340 R 906968 CDS YP_004439623.1 332297701 10579558 complement(1263779..1264336) 1 NC_015500.1 KEGG: mgl:MGL_0687 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919946; hypothetical protein 1264336 10579558 Trebr_1060 Treponema brennaborense DSM 12168 hypothetical protein YP_004439623.1 1263779 R 906968 CDS YP_004439624.1 332297702 10579559 complement(1264633..1265823) 1 NC_015500.1 KEGG: tde:TDE2429 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919947; hypothetical protein 1265823 10579559 Trebr_1061 Treponema brennaborense DSM 12168 hypothetical protein YP_004439624.1 1264633 R 906968 CDS YP_004439625.1 332297703 10579560 complement(1265820..1266971) 1 NC_015500.1 InterPro IPR006143; KEGG: tde:TDE0426 bacteriocin ABC transporter, bacteriocin-binding protein, PFAM: Secretion protein HlyD; SPTR: Bacteriocin ABC transporter, bacteriocin-binding protein, ; IMG reference gene:2504919948; PFAM: HlyD family secretion protein; secretion protein HlyD family protein 1266971 10579560 Trebr_1062 Treponema brennaborense DSM 12168 secretion protein HlyD family protein YP_004439625.1 1265820 R 906968 CDS YP_004439626.1 332297704 10579561 complement(1266973..1269120) 1 NC_015500.1 COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterProIPR005897:IPR003593:IPR005074:IPR001140:IPR 003439; KEGG: tde:TDE0425 bacteriocin ABC transporter, ATP-binding/permease, PFAM: ABC transporter-like; Peptidase C39, bacteriocin processing; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Bacteriocin ABC transporter, ATP-binding/permease, ; TIGRFAM: Peptidase C39, ABC-type bacteriocin transporter; IMG reference gene:2504919949; PFAM: Peptidase C39 family; ABC transporter; ABC transporter transmembrane region; TIGRFAM: ABC-type bacteriocin transporter; bacteriocin ABC transporter 1269120 10579561 Trebr_1063 Treponema brennaborense DSM 12168 bacteriocin ABC transporter YP_004439626.1 1266973 R 906968 CDS YP_004439627.1 332297705 10579562 complement(1269092..1269688) 1 NC_015500.1 IMG reference gene:2504919950; hypothetical protein 1269688 10579562 Trebr_1064 Treponema brennaborense DSM 12168 hypothetical protein YP_004439627.1 1269092 R 906968 CDS YP_004439628.1 332297706 10579563 complement(1269719..1270870) 1 NC_015500.1 IMG reference gene:2504919951; hypothetical protein 1270870 10579563 Trebr_1065 Treponema brennaborense DSM 12168 hypothetical protein YP_004439628.1 1269719 R 906968 CDS YP_004439629.1 332297707 10579564 complement(1270883..1271383) 1 NC_015500.1 IMG reference gene:2504919952; hypothetical protein 1271383 10579564 Trebr_1066 Treponema brennaborense DSM 12168 hypothetical protein YP_004439629.1 1270883 R 906968 CDS YP_004439630.1 332297708 10579565 complement(1271414..1272571) 1 NC_015500.1 IMG reference gene:2504919953; hypothetical protein 1272571 10579565 Trebr_1067 Treponema brennaborense DSM 12168 hypothetical protein YP_004439630.1 1271414 R 906968 CDS YP_004439631.1 332297709 10579566 complement(1272621..1274249) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mif:Metin_0252 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1; IMG reference gene:2504919954; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; group 1 glycosyl transferase 1274249 10579566 Trebr_1068 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004439631.1 1272621 R 906968 CDS YP_004439632.1 332297710 10579567 1274890..1276131 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504919955; PFAM: Transposase, Mutator family; transposase mutator type 1276131 10579567 Trebr_1069 Treponema brennaborense DSM 12168 transposase mutator type YP_004439632.1 1274890 D 906968 CDS YP_004439633.1 332297711 10579568 complement(1276114..1276779) 1 NC_015500.1 InterPro IPR001611; KEGG: tan:TA07655 protein phosphatase regulator subunit; PFAM: Leucine-rich repeat; SPTR: Protein phosphatase regulator subunit, ; IMG reference gene:2504919956; PFAM: Leucine Rich Repeat; leucine-rich repeat-containing protein 1276779 10579568 Trebr_1070 Treponema brennaborense DSM 12168 leucine-rich repeat-containing protein YP_004439633.1 1276114 R 906968 CDS YP_004439634.1 332297712 10579569 complement(1276800..1277444) 1 NC_015500.1 IMG reference gene:2504919957; hypothetical protein 1277444 10579569 Trebr_1071 Treponema brennaborense DSM 12168 hypothetical protein YP_004439634.1 1276800 R 906968 CDS YP_004439635.1 332297713 10579570 complement(1277939..1278082) 1 NC_015500.1 KEGG: ppn:Palpr_2768 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919958; PFAM: Protein of unknown function (DUF1451); hypothetical protein 1278082 10579570 Trebr_1072 Treponema brennaborense DSM 12168 hypothetical protein YP_004439635.1 1277939 R 906968 CDS YP_004439636.1 332297714 10579571 1278173..1278385 1 NC_015500.1 IMG reference gene:2504919959; hypothetical protein 1278385 10579571 Trebr_1073 Treponema brennaborense DSM 12168 hypothetical protein YP_004439636.1 1278173 D 906968 CDS YP_004439637.1 332297715 10579572 complement(1278426..1280387) 1 NC_015500.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterPro IPR004739:IPR000991:IPR001674; KEGG: fsu:Fisuc_2984 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; SPTR: GMP synthase, pp-ATPase domain/subunit; TIGRFAM: GMP synthase, N-terminal; IMG reference gene:2504919960; PFAM: Glutamine amidotransferase class-I; GMP synthase C terminal domain; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; GMP synthase, small subunit 1280387 10579572 Trebr_1074 Treponema brennaborense DSM 12168 GMP synthase, small subunit YP_004439637.1 1278426 R 906968 CDS YP_004439638.1 332297716 10579573 complement(1280384..1282060) 1 NC_015500.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); HAMAP: CTP synthase; InterPro IPR004468:IPR017456:IPR000991; KEGG: tde:TDE2692 CTP synthetase; PFAM: CTP synthase, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; IMG reference gene:2504919961; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase; CTP synthase 1282060 10579573 Trebr_1075 Treponema brennaborense DSM 12168 CTP synthase YP_004439638.1 1280384 R 906968 CDS YP_004439639.1 332297717 10579574 complement(1282155..1283423) 1 NC_015500.1 COGs: COG1295 membrane protein; InterPro IPR000595:IPR004664; KEGG: tde:TDE0150 ribonuclease BN-like family protein; PFAM: Cyclic nucleotide-binding; Ribonuclease BN-related; SMART: Cyclic nucleotide-binding; SPTR: Ribonuclease BN-like family protein; IMG reference gene:2504919962; PFAM: Ribonuclease BN-like family; Cyclic nucleotide-binding domain; cyclic nucleotide-binding protein 1283423 10579574 Trebr_1076 Treponema brennaborense DSM 12168 cyclic nucleotide-binding protein YP_004439639.1 1282155 R 906968 CDS YP_004439640.1 332297718 10579575 1283623..1284066 1 NC_015500.1 COGs: COG0105 Nucleoside diphosphate kinase; HAMAP: Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: apo:Arcpr_0498 nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504919963; PFAM: Nucleoside diphosphate kinase; nucleoside diphosphate kinase 1284066 10579575 Trebr_1077 Treponema brennaborense DSM 12168 nucleoside diphosphate kinase YP_004439640.1 1283623 D 906968 CDS YP_004439641.1 332297719 10579576 1284076..1285125 1 NC_015500.1 COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; InterPro IPR011128:IPR006109; KEGG: tde:TDE2090 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; IMG reference gene:2504919964; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Glycerol-3-phosphate dehydrogenase (NAD(P)+) 1285125 10579576 Trebr_1078 Treponema brennaborense DSM 12168 Glycerol-3-phosphate dehydrogenase (NAD(P)+) YP_004439641.1 1284076 D 906968 CDS YP_004439642.1 332297720 10579577 1285135..1286352 1 NC_015500.1 COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); HAMAP: Arginine biosynthesis protein ArgJ; InterPro IPR002813; KEGG: arginine biosynthesis bifunctional protein ArgJ; PFAM: Arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: Arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: Arginine biosynthesis protein ArgJ; IMG reference gene:2504919965; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase; arginine biosynthesis bifunctional protein ArgJ 1286352 10579577 Trebr_1079 Treponema brennaborense DSM 12168 arginine biosynthesis bifunctional protein ArgJ YP_004439642.1 1285135 D 906968 CDS YP_004439643.1 332297721 10579578 1286370..1287236 1 NC_015500.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR004662:IPR001048; KEGG: acetylglutamate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: Acetylglutamate kinase; IMG reference gene:2504919966; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase; acetylglutamate kinase 1287236 10579578 Trebr_1080 Treponema brennaborense DSM 12168 acetylglutamate kinase YP_004439643.1 1286370 D 906968 CDS YP_004439644.1 332297722 10579579 1287265..1288467 1 NC_015500.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: mta:Moth_2287 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: uncharacterized protein; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; IMG reference gene:2504919967; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Acetylornithine/succinyldiaminopimelate aminotransferase 1288467 10579579 Trebr_1081 Treponema brennaborense DSM 12168 Acetylornithine/succinyldiaminopimelate aminotransferase YP_004439644.1 1287265 D 906968 CDS YP_004439645.1 332297723 10579580 complement(1288479..1289513) 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843; KEGG: sta:STHERM_c20570 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family; IMG reference gene:2504919968; PFAM: Bacterial regulatory proteins, lacI family; LacI family transcriptional regulator 1289513 10579580 Trebr_1082 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004439645.1 1288479 R 906968 CDS YP_004439646.1 332297724 10579581 1289828..1291033 1 NC_015500.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tde:TDE2217 galactose/glucose-binding lipoprotein; SPTR: Galactose/glucose-binding lipoprotein; IMG reference gene:2504919969; galactose/glucose-binding lipoprotein 1291033 10579581 Trebr_1083 Treponema brennaborense DSM 12168 galactose/glucose-binding lipoprotein YP_004439646.1 1289828 D 906968 CDS YP_004439647.1 332297725 10579582 1291184..1292677 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE2216 galactoside ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Galactose/methyl galactoside import ATP-binding protein MglA; IMG reference gene:2504919970; PFAM: ABC transporter; monosaccharide-transporting ATPase 1292677 10579582 Trebr_1084 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439647.1 1291184 D 906968 CDS YP_004439648.1 332297726 10579583 1292704..1294404 1 NC_015500.1 COGs: COG4211 ABC-type glucose/galactose transport system permease component; InterPro IPR001851; KEGG: tde:TDE2215 galactoside ABC transporter, permease protein, PFAM: Bacterial inner-membrane translocator; SPTR: Galactoside ABC transporter, permease protein, ; IMG reference gene:2504919971; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 1294404 10579583 Trebr_1085 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439648.1 1292704 D 906968 CDS YP_004439649.1 332297727 10579584 complement(1294502..1295470) 1 NC_015500.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: aco:Amico_1665 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG/KHG aldolase; PRIAM: 2-dehydro-3-deoxy-phosphogluconate aldolase; SPTR: Entner-Doudoroff aldolase; TIGRFAM: KDPG/KHG aldolase; IMG reference gene:2504919972; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 1295470 10579584 Trebr_1086 Treponema brennaborense DSM 12168 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_004439649.1 1294502 R 906968 CDS YP_004439650.1 332297728 10579585 complement(1295606..1295974) 1 NC_015500.1 InterPro IPR001845; KEGG: dhd:Dhaf_2130 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR; IMG reference gene:2504919973; PFAM: Bacterial regulatory protein, arsR family; regulatory protein ArsR 1295974 10579585 Trebr_1087 Treponema brennaborense DSM 12168 regulatory protein ArsR YP_004439650.1 1295606 R 906968 CDS YP_004439651.1 332297729 10579586 complement(1296079..1298208) 1 NC_015500.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: tde:TDE2190 single-stranded-DNA-specific exonuclease RecJ; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; IMG reference gene:2504919974; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; single-stranded-DNA-specific exonuclease RecJ 1298208 10579586 Trebr_1088 Treponema brennaborense DSM 12168 single-stranded-DNA-specific exonuclease RecJ YP_004439651.1 1296079 R 906968 CDS YP_004439652.1 332297730 10579587 complement(1298302..1299111) 1 NC_015500.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); HAMAP: DNA repair protein recO; InterPro IPR003717; KEGG: tde:TDE0436 recombination protein O; PFAM: Recombination protein O, RecO; SPTR: Recombination protein O; TIGRFAM: Recombination protein O, RecO; IMG reference gene:2504919975; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO; DNA repair protein recO 1299111 10579587 Trebr_1089 Treponema brennaborense DSM 12168 DNA repair protein recO YP_004439652.1 1298302 R 906968 CDS YP_004439653.1 332297731 10579588 1299256..1300545 1 NC_015500.1 COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR003402; KEGG: sth:STH3137 SAM-dependent methyltransferase; PFAM: Protein of unknown function Met10; SPTR: SAM-dependent methyltransferase; IMG reference gene:2504919976; PFAM: S-adenosylmethionine-dependent methyltransferase; hypothetical protein 1300545 10579588 Trebr_1090 Treponema brennaborense DSM 12168 hypothetical protein YP_004439653.1 1299256 D 906968 CDS YP_004439654.1 332297732 10579589 1300545..1301495 1 NC_015500.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; HAMAP: tRNA dimethylallyltransferase; InterPro IPR018022:IPR002627; KEGG: tde:TDE1447 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase 2; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; IMG reference gene:2504919977; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase; tRNA dimethylallyltransferase 1301495 10579589 Trebr_1091 Treponema brennaborense DSM 12168 tRNA dimethylallyltransferase YP_004439654.1 1300545 D 906968 CDS YP_004439655.1 332297733 10579590 1301486..1302829 1 NC_015500.1 KEGG: ppd:Ppro_0504 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919978; hypothetical protein 1302829 10579590 Trebr_1092 Treponema brennaborense DSM 12168 hypothetical protein YP_004439655.1 1301486 D 906968 CDS YP_004439656.1 332297734 10579591 complement(1302819..1303034) 1 NC_015500.1 KEGG: tde:TDE0967 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504919979; hypothetical protein 1303034 10579591 Trebr_1093 Treponema brennaborense DSM 12168 hypothetical protein YP_004439656.1 1302819 R 906968 CDS YP_004439657.1 332297735 10579592 1303156..1303911 1 NC_015500.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130; KEGG: tde:TDE0966 TatD family hydrolase; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; IMG reference gene:2504919980; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; TatD-related deoxyribonuclease 1303911 10579592 Trebr_1094 Treponema brennaborense DSM 12168 TatD-related deoxyribonuclease YP_004439657.1 1303156 D 906968 CDS YP_004439658.1 332297736 10579593 complement(1303906..1304274) 1 NC_015500.1 InterPro IPR008207; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; SPTR: Probable sensor/response regulator hybrid protein; IMG reference gene:2504919981; PFAM: Hpt domain; Hpt domain-containing protein 1304274 10579593 Trebr_1095 Treponema brennaborense DSM 12168 Hpt domain-containing protein YP_004439658.1 1303906 R 906968 CDS YP_004439659.1 332297737 10579594 1304320..1306107 1 NC_015500.1 COGs: COG0681 Signal peptidase I; InterPro IPR019759; KEGG: tde:TDE2219 hypothetical protein; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I domain protein; IMG reference gene:2504919982; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Peptidase S24/S26A/S26B, conserved region 1306107 10579594 Trebr_1096 Treponema brennaborense DSM 12168 Peptidase S24/S26A/S26B, conserved region YP_004439659.1 1304320 D 906968 CDS YP_004439660.1 332297738 10579595 1306266..1307483 1 NC_015500.1 COGs: COG3325 Chitinase; InterPro IPR011583:IPR001223; KEGG: cpy:Cphy_2572 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 18, catalytic domain; SMART: Chitinase II; SPTR: Glycoside hydrolase family 18; IMG reference gene:2504919983; PFAM: Glycosyl hydrolases family 18; glycoside hydrolase family protein 1307483 10579595 Trebr_1097 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004439660.1 1306266 D 906968 CDS YP_004439661.1 332297739 10579596 complement(1307590..1308429) 1 NC_015500.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dae:Dtox_0335 ABC-3 protein; PFAM: ABC-3; SPTR: cation ABC transporter, permease protein; IMG reference gene:2504919984; PFAM: ABC 3 transport family; ABC transporter permease 1308429 10579596 Trebr_1098 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439661.1 1307590 R 906968 CDS YP_004439662.1 332297740 10579597 complement(1308426..1309301) 1 NC_015500.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: cce:Ccel_3414 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC superfamily ATP binding cassette transporter, ABC protein; IMG reference gene:2504919985; PFAM: ABC transporter; ABC transporter 1309301 10579597 Trebr_1099 Treponema brennaborense DSM 12168 ABC transporter YP_004439662.1 1308426 R 906968 CDS YP_004439663.1 332297741 10579598 complement(1309403..1310296) 1 NC_015500.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR020821:IPR001604; KEGG: cts:Ctha_1807 DNA/RNA non-specific endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: Extracellular Endonuclease, subunit A; SPTR: DNA/RNA non-specific endonuclease; IMG reference gene:2504919986; PFAM: DNA/RNA non-specific endonuclease; DNA/RNA non-specific endonuclease 1310296 10579598 Trebr_1100 Treponema brennaborense DSM 12168 DNA/RNA non-specific endonuclease YP_004439663.1 1309403 R 906968 CDS YP_004439664.1 332297742 10579599 1310423..1310734 1 NC_015500.1 InterPro IPR003837; KEGG: tde:TDE0577 glutamyl-tRNA(Gln) amidotransferase, C subunit; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit C; TIGRFAM: Glu-tRNAGln amidotransferase, C subunit; IMG reference gene:2504919987; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; glutamyl-tRNA(Gln) amidotransferase subunit C 1310734 10579599 Trebr_1101 Treponema brennaborense DSM 12168 glutamyl-tRNA(Gln) amidotransferase subunit C YP_004439664.1 1310423 D 906968 CDS YP_004439665.1 332297743 10579600 1310737..1312284 1 NC_015500.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; HAMAP: Glutamyl-tRNA(Gln) amidotransferase A subunit; InterPro IPR004412:IPR000120; KEGG: tde:TDE0576 aspartyl/glutamyl-tRNA amidotransferase subunit A; PFAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase A subunit; IMG reference gene:2504919988; PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Glutamyl-tRNA(Gln) amidotransferase subunit A 1312284 10579600 Trebr_1102 Treponema brennaborense DSM 12168 Glutamyl-tRNA(Gln) amidotransferase subunit A YP_004439665.1 1310737 D 906968 CDS YP_004439666.1 332297744 10579601 1312281..1313816 1 NC_015500.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); HAMAP: Glutamyl-tRNA(Gln) amidotransferase, B subunit; InterPro IPR004413:IPR006075:IPR006107:IPR018027; KEGG: tde:TDE0575 aspartyl/glutamyl-tRNA amidotransferase subunit B; PFAM: Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, central region; Asn/Gln amidotransferase; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase, B subunit; IMG reference gene:2504919989; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; aspartyl/glutamyl-tRNA amidotransferase subunit B 1313816 10579601 Trebr_1103 Treponema brennaborense DSM 12168 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_004439666.1 1312281 D 906968 CDS YP_004439667.1 332297745 10579602 1313831..1314772 1 NC_015500.1 KEGG: tpp:TPASS_0678 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919990; PFAM: Aminotransferase class-III; hypothetical protein 1314772 10579602 Trebr_1104 Treponema brennaborense DSM 12168 hypothetical protein YP_004439667.1 1313831 D 906968 CDS YP_004439668.1 332297746 10579603 1314759..1315055 1 NC_015500.1 KEGG: ssm:Spirs_3755 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919991; hypothetical protein 1315055 10579603 Trebr_1105 Treponema brennaborense DSM 12168 hypothetical protein YP_004439668.1 1314759 D 906968 CDS YP_004439669.1 332297747 10579604 1315128..1315538 1 NC_015500.1 KEGG: tde:TDE1018 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504919992; hypothetical protein 1315538 10579604 Trebr_1106 Treponema brennaborense DSM 12168 hypothetical protein YP_004439669.1 1315128 D 906968 CDS YP_004439670.1 332297748 10579606 1315924..1317990 1 NC_015500.1 COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: cdl:CDR20291_0742 signaling protein; PFAM: Diguanylate phosphodiesterase, predicted; SMART: Diguanylate phosphodiesterase, predicted; SPTR: Probable signaling protein; IMG reference gene:2504919994; PFAM: EAL domain; GGDEF domain; diguanylate phosphodiesterase 1317990 10579606 Trebr_1107 Treponema brennaborense DSM 12168 diguanylate phosphodiesterase YP_004439670.1 1315924 D 906968 CDS YP_004439671.1 332297749 10579607 complement(1318138..1319859) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: gsu:GSU1298 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504919995; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1319859 10579607 Trebr_1108 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439671.1 1318138 R 906968 CDS YP_004439672.1 332297750 10579608 complement(1320197..1320859) 1 NC_015500.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: cts:Ctha_1646 haloacid dehalogenase domain-containing protein hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; IMG reference gene:2504919996; PFAM: haloacid dehalogenase-like hydrolase; haloacid dehalogenase domain-containing protein hydrolase 1320859 10579608 Trebr_1109 Treponema brennaborense DSM 12168 haloacid dehalogenase domain-containing protein hydrolase YP_004439672.1 1320197 R 906968 CDS YP_004439673.1 332297751 10579609 complement(1320856..1322100) 1 NC_015500.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: tde:TDE2722 carbhohydrate kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; SPTR: Carhohydrate kinase, FGGY family; IMG reference gene:2504919997; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; Carbohydrate kinase, FGGY 1322100 10579609 Trebr_1110 Treponema brennaborense DSM 12168 Carbohydrate kinase, FGGY YP_004439673.1 1320856 R 906968 CDS YP_004439674.1 332297752 10579610 complement(1322100..1323338) 1 NC_015500.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: tde:TDE2723 phosphoribosylpyrophosphate synthetase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Phosphoribosylpyrophosphate synthetase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504919998; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; ribose-phosphate pyrophosphokinase 1323338 10579610 Trebr_1111 Treponema brennaborense DSM 12168 ribose-phosphate pyrophosphokinase YP_004439674.1 1322100 R 906968 CDS YP_004439675.1 332297753 10579611 1323605..1325266 1 NC_015500.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR011183:IPR000023; KEGG: sta:STHERM_c17480 pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; PFAM: Phosphofructokinase; SPTR: Pyrophosphate-dependent phosphofructokinase; TIGRFAM: Pyrophosphate-dependent phosphofructokinase PfpB; IMG reference gene:2504919999; PFAM: Phosphofructokinase; TIGRFAM: diphosphate--fructose-6-phosphate 1-phosphotransferase; diphosphate/fructose-6-phosphate 1-phosphotransferase 1325266 10579611 Trebr_1112 Treponema brennaborense DSM 12168 diphosphate/fructose-6-phosphate 1-phosphotransferase YP_004439675.1 1323605 D 906968 CDS YP_004439676.1 332297754 10579612 complement(1325336..1325593) 1 NC_015500.1 InterPro IPR005358; KEGG: etr:ETAE_2286 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Proteinase inhibitor; manually curated; IMG reference gene:2504920000; hypothetical protein 1325593 10579612 Trebr_1113 Treponema brennaborense DSM 12168 hypothetical protein YP_004439676.1 1325336 R 906968 CDS YP_004439677.1 332297755 10579613 1325716..1327038 1 NC_015500.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: tde:TDE1966 trypsin domain/PDZ domain-containing protein; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Protease do; IMG reference gene:2504920001; PFAM: Trypsin; peptidase S1 and S6 chymotrypsin/Hap 1327038 10579613 Trebr_1114 Treponema brennaborense DSM 12168 peptidase S1 and S6 chymotrypsin/Hap YP_004439677.1 1325716 D 906968 CDS YP_004439678.1 332297756 10579614 1327047..1329044 1 NC_015500.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; HAMAP: Excinuclease ABC, B subunit; InterProIPR004807:IPR014001:IPR001650:IPR006935:IPR 001943; KEGG: tde:TDE1369 excinuclease ABC subunit B; PFAM: DNA/RNA helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: UvrABC system protein B; TIGRFAM: Excinuclease ABC, B subunit; IMG reference gene:2504920002; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit; UvrABC system protein B 1329044 10579614 Trebr_1115 Treponema brennaborense DSM 12168 UvrABC system protein B YP_004439678.1 1327047 D 906968 CDS YP_004439679.1 332297757 10579615 complement(1329120..1330400) 1 NC_015500.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: gym:GYMC10_2506 nitrite reductase (NAD(P)H), large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Nitrite reductase (NAD(P)H); SPTR: Nitrite reductase (NAD(P)H), large subunit; IMG reference gene:2504920003; PFAM: Pyridine nucleotide-disulphide oxidoreductase; nitrite reductase (NAD(P)H) 1330400 10579615 Trebr_1116 Treponema brennaborense DSM 12168 nitrite reductase (NAD(P)H) YP_004439679.1 1329120 R 906968 CDS YP_004439680.1 332297758 10579616 1330528..1331436 1 NC_015500.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: ssm:Spirs_3682 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; IMG reference gene:2504920004; PFAM: Metallo-beta-lactamase superfamily; beta-lactamase domain-containing protein 1331436 10579616 Trebr_1117 Treponema brennaborense DSM 12168 beta-lactamase domain-containing protein YP_004439680.1 1330528 D 906968 CDS YP_004439681.1 332297759 10579617 complement(1331440..1333242) 1 NC_015500.1 COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; KEGG: ssm:Spirs_0059 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504920005; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; pyruvate kinase 1333242 10579617 Trebr_1118 Treponema brennaborense DSM 12168 pyruvate kinase YP_004439681.1 1331440 R 906968 CDS YP_004439682.1 332297760 10579618 complement(1333359..1335548) 1 NC_015500.1 KEGG: hoh:Hoch_1608 peptidase C14 caspase catalytic subunit P20; SPTR: Peptidase C14 caspase catalytic subunit p20; IMG reference gene:2504920006; PFAM: Caspase domain; hypothetical protein 1335548 10579618 Trebr_1119 Treponema brennaborense DSM 12168 hypothetical protein YP_004439682.1 1333359 R 906968 CDS YP_004439683.1 332297761 10579619 complement(1335561..1336313) 1 NC_015500.1 KEGG: afw:Anae109_0876 hypothetical protein; SPTR: ActD; IMG reference gene:2504920007; hypothetical protein 1336313 10579619 Trebr_1120 Treponema brennaborense DSM 12168 hypothetical protein YP_004439683.1 1335561 R 906968 CDS YP_004439684.1 332297762 10579620 complement(1336303..1336818) 1 NC_015500.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284:IPR007627; KEGG: RNA polymerase sigma-70 factor, group 3; PFAM: RNA polymerase sigma-70 region 2; SPTR: RNA polymerase sigma-70 factor, group 3; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504920008; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 1336818 10579620 Trebr_1121 Treponema brennaborense DSM 12168 ECF subfamily RNA polymerase sigma-24 subunit YP_004439684.1 1336303 R 906968 CDS YP_004439685.1 332297763 10579621 complement(1337180..1338370) 1 NC_015500.1 KEGG: ssm:Spirs_3139 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920009; hypothetical protein 1338370 10579621 Trebr_1122 Treponema brennaborense DSM 12168 hypothetical protein YP_004439685.1 1337180 R 906968 CDS YP_004439686.1 332297764 10579623 1340075..1340977 1 NC_015500.1 KEGG: clj:CLJU_c30590 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920011; hypothetical protein 1340977 10579623 Trebr_1124 Treponema brennaborense DSM 12168 hypothetical protein YP_004439686.1 1340075 D 906968 CDS YP_004439687.1 332297765 10579624 1340964..1341794 1 NC_015500.1 COGs: COG1533 DNA repair photolyase; InterPro IPR007197; KEGG: amu:Amuc_1314 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504920012; PFAM: Radical SAM superfamily; Radical SAM domain protein 1341794 10579624 Trebr_1125 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004439687.1 1340964 D 906968 CDS YP_004439688.1 332297766 10579625 1341842..1342378 1 NC_015500.1 KEGG: cbk:CLL_A2046 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920013; hypothetical protein 1342378 10579625 Trebr_1126 Treponema brennaborense DSM 12168 hypothetical protein YP_004439688.1 1341842 D 906968 CDS YP_004439689.1 332297767 10579626 1342819..1344015 1 NC_015500.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR011946:IPR004107:IPR002104; KEGG: cph:Cpha266_0257 integron integrase; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Similar to site-specific tyrosine recombinase; TIGRFAM: Integrase, integron-type; IMG reference gene:2504920014; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: integron integrase; integron integrase 1344015 10579626 Trebr_1127 Treponema brennaborense DSM 12168 integron integrase YP_004439689.1 1342819 D 906968 CDS YP_004439690.1 332297768 10579627 1344585..1345421 1 NC_015500.1 SPTR: lipoprotein; IMG reference gene:2504920015; hypothetical protein 1345421 10579627 Trebr_1128 Treponema brennaborense DSM 12168 hypothetical protein YP_004439690.1 1344585 D 906968 CDS YP_004439691.1 332297769 10579628 complement(1345716..1346846) 1 NC_015500.1 COGs: COG3547 Transposase and inactivated derivatives; InterPro IPR003346; KEGG: bpb:bpr_IV010 IS110 family transposase; PFAM: Transposase, IS116/IS110/IS902; SPTR: ISCps8, transposase; IMG reference gene:2504920016; PFAM: Transposase IS116/IS110/IS902 family; Transposase; transposase IS116/IS110/IS902 family protein 1346846 10579628 Trebr_1129 Treponema brennaborense DSM 12168 transposase IS116/IS110/IS902 family protein YP_004439691.1 1345716 R 906968 CDS YP_004439692.1 332297770 10579629 1347383..1348624 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504920017; PFAM: Transposase, Mutator family; transposase mutator type 1348624 10579629 Trebr_1130 Treponema brennaborense DSM 12168 transposase mutator type YP_004439692.1 1347383 D 906968 CDS YP_004439693.1 332297771 10579632 complement(1349444..1349767) 1 NC_015500.1 KEGG: lin:lin0358 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920020; PFAM: Inorganic pyrophosphatase; hypothetical protein 1349767 10579632 Trebr_1133 Treponema brennaborense DSM 12168 hypothetical protein YP_004439693.1 1349444 R 906968 CDS YP_004439694.1 332297772 10579634 1351088..1352422 1 NC_015500.1 COGs: COG5026 Hexokinase; InterPro IPR001312; KEGG: tpp:TPASS_0505 hexokinase; PFAM: Hexokinase; PRIAM: Hexokinase; SPTR: Hexokinase; IMG reference gene:2504920022; PFAM: Hexokinase; hexokinase 1352422 10579634 Trebr_1135 Treponema brennaborense DSM 12168 hexokinase YP_004439694.1 1351088 D 906968 CDS YP_004439695.1 332297773 10579635 1352436..1355630 1 NC_015500.1 KEGG: tde:TDE1988 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920023; hypothetical protein 1355630 10579635 Trebr_1136 Treponema brennaborense DSM 12168 hypothetical protein YP_004439695.1 1352436 D 906968 CDS YP_004439696.1 332297774 10579636 complement(1355634..1356275) 1 NC_015500.1 KEGG: tde:TDE1334 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920024; hypothetical protein 1356275 10579636 Trebr_1137 Treponema brennaborense DSM 12168 hypothetical protein YP_004439696.1 1355634 R 906968 CDS YP_004439697.1 332297775 10579637 1356495..1356764 1 NC_015500.1 COGs: COG1987 Flagellar biosynthesis pathway component FliQ; InterPro IPR006305:IPR002191; KEGG: tpp:TPASS_0717 flagellar biosynthetic protein; PFAM: Bacterial export protein FliQ, family 3; SPTR: Flagellar biosynthetic protein FliQ; TIGRFAM: Flagellar biosynthesis protein FliQ; IMG reference gene:2504920025; PFAM: Bacterial export proteins, family 3; TIGRFAM: flagellar biosynthetic protein FliQ; flagellar biosynthetic protein FliQ 1356764 10579637 Trebr_1138 Treponema brennaborense DSM 12168 flagellar biosynthetic protein FliQ YP_004439697.1 1356495 D 906968 CDS YP_004439698.1 332297776 10579638 1356767..1357606 1 NC_015500.1 COGs: COG1684 Flagellar biosynthesis pathway component FliR; InterPro IPR006303:IPR002010; KEGG: tpp:TPASS_0716 flagellar biosynthetic protein; PFAM: Type III secretion system inner membrane R protein; SPTR: Flagellar biosynthetic protein fliR; TIGRFAM: Flagellar biosynthesis protein FliR; IMG reference gene:2504920026; PFAM: Bacterial export proteins, family 1; TIGRFAM: flagellar biosynthetic protein FliR; flagellar biosynthetic protein FliR 1357606 10579638 Trebr_1139 Treponema brennaborense DSM 12168 flagellar biosynthetic protein FliR YP_004439698.1 1356767 D 906968 CDS YP_004439699.1 332297777 10579639 1357603..1358739 1 NC_015500.1 COGs: COG1377 Flagellar biosynthesis pathway component FlhB; InterPro IPR006136:IPR006135; KEGG: tde:TDE0054 flagellar biosynthesis protein FlhB; PFAM: Type III secretion exporter; SPTR: Flagellar biosynthetic protein FlhB; TIGRFAM: Flagellar biosynthetic protein FlhB; IMG reference gene:2504920027; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flagellar biosynthetic protein FlhB; flagellar biosynthetic protein FlhB 1358739 10579639 Trebr_1140 Treponema brennaborense DSM 12168 flagellar biosynthetic protein FlhB YP_004439699.1 1357603 D 906968 CDS YP_004439700.1 332297778 10579640 1358785..1360860 1 NC_015500.1 COGs: COG1298 Flagellar biosynthesis pathway component FlhA; InterPro IPR006301:IPR001712; KEGG: sta:STHERM_c09300 hypothetical protein; PFAM: Type III secretion system FHIPEP; SPTR: Flagellar biosynthesis protein FlhA; TIGRFAM: Flagellar biosynthesis protein FlhA; IMG reference gene:2504920028; PFAM: FHIPEP family; TIGRFAM: flagellar biosynthesis protein FlhA; flagellar biosynthesis protein FlhA 1360860 10579640 Trebr_1141 Treponema brennaborense DSM 12168 flagellar biosynthesis protein FlhA YP_004439700.1 1358785 D 906968 CDS YP_004439701.1 332297779 10579641 1360865..1362163 1 NC_015500.1 COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR003593:IPR000897; KEGG: tde:TDE2686 flagellar biosynthetic protein FlhF; PFAM: Signal recognition particle, SRP54 subunit, GTPase; SMART: ATPase, AAA+ type, core; SPTR: Flagellar biosynthetic protein FlhF; IMG reference gene:2504920029; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF; GTP-binding signal recognition particle SRP54 G- domain-containing protein 1362163 10579641 Trebr_1142 Treponema brennaborense DSM 12168 GTP-binding signal recognition particle SRP54 G- domain-containing protein YP_004439701.1 1360865 D 906968 CDS YP_004439702.1 332297780 10579642 1362166..1363035 1 NC_015500.1 COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tde:TDE2685 flagellar synthesis regulator FleN; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN; IMG reference gene:2504920030; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; Cobyrinic acid ac-diamide synthase 1363035 10579642 Trebr_1143 Treponema brennaborense DSM 12168 Cobyrinic acid ac-diamide synthase YP_004439702.1 1362166 D 906968 CDS YP_004439703.1 332297781 10579643 1363097..1363873 1 NC_015500.1 KEGG: sta:STHERM_c09330 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920031; hypothetical protein 1363873 10579643 Trebr_1144 Treponema brennaborense DSM 12168 hypothetical protein YP_004439703.1 1363097 D 906968 CDS YP_004439704.1 332297782 10579644 1363898..1364686 1 NC_015500.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR014284:IPR012845:IPR007627:IPR007624:IPR 007630; KEGG: ssm:Spirs_1586 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase sigma-70; IMG reference gene:2504920032; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma 28 subunit FliA/WhiG 1364686 10579644 Trebr_1145 Treponema brennaborense DSM 12168 RNA polymerase sigma 28 subunit FliA/WhiG YP_004439704.1 1363898 D 906968 CDS YP_004439705.1 332297783 10579645 1364742..1366715 1 NC_015500.1 COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: tde:TDE2682 hypothetical protein; PFAM: Protein of unknown function DUF342; SPTR: uncharacterized protein; IMG reference gene:2504920033; PFAM: Protein of unknown function (DUF342); hypothetical protein 1366715 10579645 Trebr_1146 Treponema brennaborense DSM 12168 hypothetical protein YP_004439705.1 1364742 D 906968 CDS YP_004439706.1 332297784 10579646 1366696..1367037 1 NC_015500.1 KEGG: tde:TDE2681 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920034; hypothetical protein 1367037 10579646 Trebr_1147 Treponema brennaborense DSM 12168 hypothetical protein YP_004439706.1 1366696 D 906968 CDS YP_004439707.1 332297785 10579647 1367040..1367675 1 NC_015500.1 KEGG: tde:TDE2680 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920035; hypothetical protein 1367675 10579647 Trebr_1148 Treponema brennaborense DSM 12168 hypothetical protein YP_004439707.1 1367040 D 906968 CDS YP_004439708.1 332297786 10579648 complement(1367751..1368656) 1 NC_015500.1 KEGG: ssm:Spirs_0019 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920036; hypothetical protein 1368656 10579648 Trebr_1149 Treponema brennaborense DSM 12168 hypothetical protein YP_004439708.1 1367751 R 906968 CDS YP_004439709.1 332297787 10579650 1369129..1370064 1 NC_015500.1 COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: tpp:TPASS_0502 hypothetical protein; SPTR: Ankyrin repeat protein; IMG reference gene:2504920038; PFAM: Ankyrin repeat; hypothetical protein 1370064 10579650 Trebr_1150 Treponema brennaborense DSM 12168 hypothetical protein YP_004439709.1 1369129 D 906968 CDS YP_004439710.1 332297788 10579651 1370070..1371233 1 NC_015500.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; HAMAP:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; InterPro IPR006009:IPR004276:IPR007235; KEGG: tde:TDE1974 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; PFAM: Glycosyl transferase, family 28; Glycosyl transferase, family 28, C-terminal; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM: N-acetylglucosaminyltransferase, MurG; IMG reference gene:2504920039; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase 1371233 10579651 Trebr_1151 Treponema brennaborense DSM 12168 UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase YP_004439710.1 1370070 D 906968 CDS YP_004439711.1 332297789 10579652 1371230..1371712 1 NC_015500.1 InterPro IPR003825; KEGG: tde:TDE1973 CvpA family protein; PFAM: Colicin V production protein; SPTR: CvpA family protein; IMG reference gene:2504920040; PFAM: Colicin V production protein; colicin V production protein 1371712 10579652 Trebr_1152 Treponema brennaborense DSM 12168 colicin V production protein YP_004439711.1 1371230 D 906968 CDS YP_004439712.1 332297790 10579653 1371712..1372965 1 NC_015500.1 KEGG: tde:TDE1971 DNA polymerase III domain-containing protein; SPTR: DNA polymerase III domain protein; IMG reference gene:2504920041; DNA polymerase III domain-containing protein 1372965 10579653 Trebr_1153 Treponema brennaborense DSM 12168 DNA polymerase III domain-containing protein YP_004439712.1 1371712 D 906968 CDS YP_004439713.1 332297791 10579654 1372962..1374155 1 NC_015500.1 COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: ssm:Spirs_1708 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; IMG reference gene:2504920042; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor signal transduction histidine kinase 1374155 10579654 Trebr_1154 Treponema brennaborense DSM 12168 PAS/PAC sensor signal transduction histidine kinase YP_004439713.1 1372962 D 906968 CDS YP_004439714.1 332297792 10579655 1374165..1375592 1 NC_015500.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: tde:TDE1969 sigma-54 dependent transcriptional regulator/response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core; SPTR: Acetoacetate metabolism regulatory protein AtoC; IMG reference gene:2504920043; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; two component, sigma54 specific, transcriptional regulator, Fis family 1375592 10579655 Trebr_1155 Treponema brennaborense DSM 12168 two component, sigma54 specific, transcriptional regulator, Fis family YP_004439714.1 1374165 D 906968 CDS YP_004439715.1 332297793 10579656 complement(1375593..1376045) 1 NC_015500.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cpy:Cphy_2561 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504920044; PFAM: MarR family; MarR family transcriptional regulator 1376045 10579656 Trebr_1156 Treponema brennaborense DSM 12168 MarR family transcriptional regulator YP_004439715.1 1375593 R 906968 CDS YP_004439716.1 332297794 10579657 complement(1376042..1376491) 1 NC_015500.1 COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: gur:Gura_1554 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; IMG reference gene:2504920045; PFAM: Pyridoxamine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-related FMN-binding protein 1376491 10579657 Trebr_1157 Treponema brennaborense DSM 12168 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein YP_004439716.1 1376042 R 906968 CDS YP_004439717.1 332297795 10579659 complement(1376915..1377616) 1 NC_015500.1 InterPro IPR019657; KEGG: tde:TDE1406 hypothetical protein; PFAM: Late competence development protein ComFB; SPTR: uncharacterized protein; IMG reference gene:2504920047; PFAM: Late competence development protein ComFB; Late competence development protein ComFB 1377616 10579659 Trebr_1158 Treponema brennaborense DSM 12168 Late competence development protein ComFB YP_004439717.1 1376915 R 906968 CDS YP_004439718.1 332297796 10579660 complement(1377617..1378861) 1 NC_015500.1 COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607:IPR006674; KEGG: tde:TDE1407 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: uncharacterized protein; IMG reference gene:2504920048; PFAM: HD domain; metal dependent phosphohydrolase 1378861 10579660 Trebr_1159 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004439718.1 1377617 R 906968 CDS YP_004439719.1 332297797 10579661 complement(1378878..1380914) 1 NC_015500.1 COGs: COG1048 Aconitase A; InterPro IPR006250:IPR001030:IPR000573; KEGG: ssm:Spirs_2351 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Aconitate hydratase; TIGRFAM: Aconitase, IMG reference gene:2504920049; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, , Aquifex type; aconitate hydratase 1380914 10579661 Trebr_1160 Treponema brennaborense DSM 12168 aconitate hydratase YP_004439719.1 1378878 R 906968 CDS YP_004439720.1 332297798 10579662 1381225..1381416 1 NC_015500.1 InterPro IPR006110; KEGG: tde:TDE0056 DNA-directed RNA polymerase, omega subunit, PFAM: RNA polymerase Rpb6; SPTR: DNA-directed RNA polymerase, omega subunit, ; IMG reference gene:2504920050; PFAM: RNA polymerase Rpb6; RNA polymerase Rpb6 1381416 10579662 Trebr_1161 Treponema brennaborense DSM 12168 RNA polymerase Rpb6 YP_004439720.1 1381225 D 906968 CDS YP_004439721.1 332297799 10579663 1381416..1382411 1 NC_015500.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; HAMAP: tRNA dimethylallyltransferase; InterPro IPR018022:IPR002627; KEGG: tde:TDE0057 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; IMG reference gene:2504920051; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase; tRNA dimethylallyltransferase 1382411 10579663 Trebr_1162 Treponema brennaborense DSM 12168 tRNA dimethylallyltransferase YP_004439721.1 1381416 D 906968 CDS YP_004439722.1 332297800 10579664 1382645..1384564 1 NC_015500.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; HAMAP: Deoxyxylulose-5-phosphate synthase; InterPro IPR005477:IPR005475:IPR005476; KEGG: tde:TDE1910 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: Deoxyxylulose-5-phosphate synthase; IMG reference gene:2504920052; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 1384564 10579664 Trebr_1163 Treponema brennaborense DSM 12168 1-deoxy-D-xylulose-5-phosphate synthase YP_004439722.1 1382645 D 906968 CDS YP_004439723.1 332297801 10579665 1384561..1385412 1 NC_015500.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: sta:STHERM_c18380 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504920053; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase; dihydropteroate synthase 1385412 10579665 Trebr_1164 Treponema brennaborense DSM 12168 dihydropteroate synthase YP_004439723.1 1384561 D 906968 CDS YP_004439724.1 332297802 10579666 1385409..1386224 1 NC_015500.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR014046:IPR003390; KEGG: tde:TDE1909 hypothetical protein; PFAM: DNA integrity scanning protein, DisA, N-terminal; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00159; IMG reference gene:2504920054; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: TIGR00159 family protein; hypothetical protein 1386224 10579666 Trebr_1165 Treponema brennaborense DSM 12168 hypothetical protein YP_004439724.1 1385409 D 906968 CDS YP_004439725.1 332297803 10579667 1386202..1387179 1 NC_015500.1 COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: ssm:Spirs_1648 YbbR family protein; PFAM: YbbR-like; SPTR: YbbR family protein; IMG reference gene:2504920055; PFAM: YbbR-like protein; hypothetical protein 1387179 10579667 Trebr_1166 Treponema brennaborense DSM 12168 hypothetical protein YP_004439725.1 1386202 D 906968 CDS YP_004439726.1 332297804 10579668 1387195..1387569 1 NC_015500.1 COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); HAMAP: Holo-[acyl-carrier-protein] synthase; InterPro IPR002582:IPR004568:IPR008278; KEGG: tde:TDE1907 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: Phosphopantethiene-protein transferase; Holo-[acyl carrier protein] synthase; IMG reference gene:2504920056; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase; holo-ACP synthase 1387569 10579668 Trebr_1167 Treponema brennaborense DSM 12168 holo-ACP synthase YP_004439726.1 1387195 D 906968 CDS YP_004439727.1 332297805 10579669 1387598..1388503 1 NC_015500.1 COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: tde:TDE2274 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: uncharacterized protein; IMG reference gene:2504920057; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); hypothetical protein 1388503 10579669 Trebr_1168 Treponema brennaborense DSM 12168 hypothetical protein YP_004439727.1 1387598 D 906968 CDS YP_004439728.1 332297806 10579670 1388512..1389285 1 NC_015500.1 COGs: COG0101 Pseudouridylate synthase; HAMAP: Pseudouridine synthase I, TruA; InterPro IPR001406:IPR020097; KEGG: tde:TDE2275 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; PRIAM: tRNA-pseudouridine synthase I; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA; IMG reference gene:2504920058; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I; tRNA pseudouridine synthase A 1389285 10579670 Trebr_1169 Treponema brennaborense DSM 12168 tRNA pseudouridine synthase A YP_004439728.1 1388512 D 906968 CDS YP_004439729.1 332297807 10579671 complement(1389310..1391364) 1 NC_015500.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR005259:IPR014001:IPR001650:IPR011545; KEGG: tde:TDE2490 primosomal protein N'; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Primosomal protein N'; TIGRFAM: Primosomal protein n; IMG reference gene:2504920059; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N'; primosomal protein N' 1391364 10579671 Trebr_1170 Treponema brennaborense DSM 12168 primosomal protein N' YP_004439729.1 1389310 R 906968 CDS YP_004439730.1 332297808 10579672 complement(1391361..1392137) 1 NC_015500.1 COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005273:IPR005122; KEGG: tde:TDE2491 DNA polymerase domain-containing protein; PFAM: Uracil-DNA glycosylase-like; SPTR: DNA polymerase domain protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; IMG reference gene:2504920060; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4; phage SPO1 DNA polymerase-related protein 1392137 10579672 Trebr_1171 Treponema brennaborense DSM 12168 phage SPO1 DNA polymerase-related protein YP_004439730.1 1391361 R 906968 CDS YP_004439731.1 332297809 10579673 1392342..1392974 1 NC_015500.1 IMG reference gene:2504920061; hypothetical protein 1392974 10579673 Trebr_1172 Treponema brennaborense DSM 12168 hypothetical protein YP_004439731.1 1392342 D 906968 CDS YP_004439732.1 332297810 10579674 1392967..1394100 1 NC_015500.1 IMG reference gene:2504920062; hypothetical protein 1394100 10579674 Trebr_1173 Treponema brennaborense DSM 12168 hypothetical protein YP_004439732.1 1392967 D 906968 CDS YP_004439733.1 332297811 10579675 1394174..1394551 1 NC_015500.1 COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: shi:Shel_15140 desulfoferrodoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding region; SPTR: Superoxide reductase; IMG reference gene:2504920063; PFAM: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain; desulfoferrodoxin ferrous iron-binding region 1394551 10579675 Trebr_1174 Treponema brennaborense DSM 12168 desulfoferrodoxin ferrous iron-binding region YP_004439733.1 1394174 D 906968 CDS YP_004439734.1 332297812 10579676 complement(1394604..1395677) 1 NC_015500.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: ssm:Spirs_2291 protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; SPTR: uncharacterized protein; IMG reference gene:2504920064; PFAM: Domain of unknown function DUF20; hypothetical protein 1395677 10579676 Trebr_1175 Treponema brennaborense DSM 12168 hypothetical protein YP_004439734.1 1394604 R 906968 CDS YP_004439735.1 332297813 10579677 complement(1395744..1397021) 1 NC_015500.1 COGs: COG0172 Seryl-tRNA synthetase; HAMAP: Seryl-tRNA synthetase; InterPro IPR002317:IPR015866:IPR002314; KEGG: tde:TDE2307 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: Seryl-tRNA synthetase, class IIa; IMG reference gene:2504920065; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase; seryl-tRNA synthetase 1397021 10579677 Trebr_1176 Treponema brennaborense DSM 12168 seryl-tRNA synthetase YP_004439735.1 1395744 R 906968 CDS YP_004439736.1 332297814 10579678 complement(1397052..1397759) 1 NC_015500.1 COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: pla:Plav_2321 hypothetical protein; PFAM: Protein of unknown function DUF541; SPTR: uncharacterized protein; IMG reference gene:2504920066; PFAM: Protein of unknown function (DUF541); hypothetical protein 1397759 10579678 Trebr_1177 Treponema brennaborense DSM 12168 hypothetical protein YP_004439736.1 1397052 R 906968 CDS YP_004439737.1 332297815 10579679 complement(1397918..1399939) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004010:IPR003660; KEGG: ssm:Spirs_3480 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor; IMG reference gene:2504920067; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 1399939 10579679 Trebr_1178 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer with Cache sensor YP_004439737.1 1397918 R 906968 CDS YP_004439738.1 332297816 10579680 1400031..1401548 1 NC_015500.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758:IPR000713:IPR013221:IPR004101; KEGG: tde:TDE1085 UDP-N-acetylmuramate--L-alanine ligase; PFAM: Mur ligase, C-terminal; Mur ligase, N-terminal; Mur ligase, central; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate-alanine ligase; IMG reference gene:2504920068; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase; UDP-N-acetylmuramate--L-alanine ligase 1401548 10579680 Trebr_1179 Treponema brennaborense DSM 12168 UDP-N-acetylmuramate--L-alanine ligase YP_004439738.1 1400031 D 906968 CDS YP_004439739.1 332297817 10579681 1401593..1402474 1 NC_015500.1 COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR005229:IPR013527:IPR013551; KEGG: tde:TDE1086 hypothetical protein; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00255; IMG reference gene:2504920069; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein; hypothetical protein 1402474 10579681 Trebr_1180 Treponema brennaborense DSM 12168 hypothetical protein YP_004439739.1 1401593 D 906968 CDS YP_004439740.1 332297818 10579682 complement(1402580..1402993) 1 NC_015500.1 IMG reference gene:2504920070; hypothetical protein 1402993 10579682 Trebr_1181 Treponema brennaborense DSM 12168 hypothetical protein YP_004439740.1 1402580 R 906968 CDS YP_004439741.1 332297819 10579683 1403106..1404149 1 NC_015500.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: lby:Lbys_2505 aldose 1-epimerase; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase; IMG reference gene:2504920071; PFAM: Aldose 1-epimerase; aldose-1-epimerase 1404149 10579683 Trebr_1182 Treponema brennaborense DSM 12168 aldose-1-epimerase YP_004439741.1 1403106 D 906968 CDS YP_004439742.1 332297820 10579684 1404280..1404912 1 NC_015500.1 KEGG: tde:TDE1381 V-type ATP synthase subunit E; SPTR: V-type ATP synthase subunit E; IMG reference gene:2504920072; V-type ATP synthase subunit E 1404912 10579684 Trebr_1183 Treponema brennaborense DSM 12168 V-type ATP synthase subunit E YP_004439742.1 1404280 D 906968 CDS YP_004439743.1 332297821 10579685 1404913..1405458 1 NC_015500.1 KEGG: tde:TDE1380 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920073; PFAM: Protein of unknown function (DUF2764); hypothetical protein 1405458 10579685 Trebr_1184 Treponema brennaborense DSM 12168 hypothetical protein YP_004439743.1 1404913 D 906968 CDS YP_004439744.1 332297822 10579686 1405455..1407224 1 NC_015500.1 COGs: COG1155 H+-ATPase subunit A; HAMAP: V-type ATP synthase alpha chain; InterPro IPR004100:IPR000194; KEGG: tde:TDE1683 V-type ATP synthase subunit A; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; PRIAM: H(+)-transporting two-sector ATPase; SPTR: V-type ATP synthase alpha chain; IMG reference gene:2504920074; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; V-type ATP synthase subunit alpha 1407224 10579686 Trebr_1185 Treponema brennaborense DSM 12168 V-type ATP synthase subunit alpha YP_004439744.1 1405455 D 906968 CDS YP_004439745.1 332297823 10579687 1407227..1408525 1 NC_015500.1 COGs: COG1156 H+-ATPase subunit B; HAMAP: V-type ATP synthase beta chain; InterPro IPR004100:IPR000194; KEGG: tde:TDE1682 V-type ATP synthase subunit B; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; SPTR: V-type ATP synthase beta chain; IMG reference gene:2504920075; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; V-type ATP synthase subunit beta 1408525 10579687 Trebr_1186 Treponema brennaborense DSM 12168 V-type ATP synthase subunit beta YP_004439745.1 1407227 D 906968 CDS YP_004439746.1 332297824 10579688 1408538..1409164 1 NC_015500.1 COGs: COG1394 H+-ATPase subunit D; HAMAP: V-type ATP synthase subunit D; InterPro IPR002699; KEGG: tde:TDE1681 V-type ATP synthase subunit D; PFAM: ATPase, V1/A1 complex, subunit D; SPTR: V-type ATPase, D subunit; TIGRFAM: ATPase, V1/A1 complex, subunit D; IMG reference gene:2504920076; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D; V-type ATP synthase subunit D 1409164 10579688 Trebr_1187 Treponema brennaborense DSM 12168 V-type ATP synthase subunit D YP_004439746.1 1408538 D 906968 CDS YP_004439747.1 332297825 10579689 1409161..1411122 1 NC_015500.1 COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: tpp:TPASS_0429 V-type ATP synthase subunit I; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: V-type ATP synthase subunit I 1; IMG reference gene:2504920077; PFAM: V-type ATPase 116kDa subunit family; V-type ATPase 116 kDa subunit 1411122 10579689 Trebr_1188 Treponema brennaborense DSM 12168 V-type ATPase 116 kDa subunit YP_004439747.1 1409161 D 906968 CDS YP_004439748.1 332297826 10579690 1411147..1411566 1 NC_015500.1 KEGG: tpp:TPASS_0430 V-type ATP synthase subunit K; SPTR: V-type ATP synthase subunit K; IMG reference gene:2504920078; PFAM: ATP synthase subunit C; V-type ATP synthase subunit K 1411566 10579690 Trebr_1189 Treponema brennaborense DSM 12168 V-type ATP synthase subunit K YP_004439748.1 1411147 D 906968 CDS YP_004439749.1 332297827 10579691 1411581..1412672 1 NC_015500.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; HAMAP: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; InterPro IPR004588; KEGG: tpp:TPASS_0446 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; IMG reference gene:2504920079; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1412672 10579691 Trebr_1190 Treponema brennaborense DSM 12168 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_004439749.1 1411581 D 906968 CDS YP_004439750.1 332297828 10579692 1412669..1413784 1 NC_015500.1 KEGG: tde:TDE1264 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920080; hypothetical protein 1413784 10579692 Trebr_1191 Treponema brennaborense DSM 12168 hypothetical protein YP_004439750.1 1412669 D 906968 CDS YP_004439751.1 332297829 10579693 complement(1413808..1415313) 1 NC_015500.1 KEGG: tde:TDE0688 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920081; hypothetical protein 1415313 10579693 Trebr_1192 Treponema brennaborense DSM 12168 hypothetical protein YP_004439751.1 1413808 R 906968 CDS YP_004439752.1 332297830 10579694 complement(1415313..1416761) 1 NC_015500.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017472:IPR017475:IPR003362; KEGG: cyn:Cyan7425_4214 undecaprenyl-phosphate galactose phosphotransferase, WbaP; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504920082; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP; UDP-phosphate galactose phosphotransferase 1416761 10579694 Trebr_1193 Treponema brennaborense DSM 12168 UDP-phosphate galactose phosphotransferase YP_004439752.1 1415313 R 906968 CDS YP_004439753.1 332297831 10579695 complement(1416832..1417590) 1 NC_015500.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840:IPR007197; KEGG: tde:TDE1856 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic-like; IMG reference gene:2504920083; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; anaerobic ribonucleoside-triphosphate reductase activating protein 1417590 10579695 Trebr_1194 Treponema brennaborense DSM 12168 anaerobic ribonucleoside-triphosphate reductase activating protein YP_004439753.1 1416832 R 906968 CDS YP_004439754.1 332297832 10579696 complement(1417598..1418137) 1 NC_015500.1 KEGG: ssm:Spirs_1454 anaerobic ribonucleoside-triphosphate reductase; SPTR: anaerobic ribonucleoside-triphosphate reductase; IMG reference gene:2504920084; anaerobic ribonucleoside-triphosphate reductase 1418137 10579696 Trebr_1195 Treponema brennaborense DSM 12168 anaerobic ribonucleoside-triphosphate reductase YP_004439754.1 1417598 R 906968 CDS YP_004439755.1 332297833 10579697 complement(1418225..1420345) 1 NC_015500.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833:IPR005144; KEGG: tde:TDE1331 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; IMG reference gene:2504920085; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; anaerobic ribonucleoside-triphosphate reductase 1420345 10579697 Trebr_1196 Treponema brennaborense DSM 12168 anaerobic ribonucleoside-triphosphate reductase YP_004439755.1 1418225 R 906968 CDS YP_004439756.1 332297834 10579698 complement(1420338..1420802) 1 NC_015500.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; HAMAP: Transcriptional repressor nrdR; InterPro IPR003796:IPR005144; KEGG: tde:TDE1330 transcriptional regulator NrdR; PFAM: ATP-cone; SPTR: Transcriptional repressor NrdR; TIGRFAM: Ribonucleotide reductase regulator NrdR-like; IMG reference gene:2504920086; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR; Transcriptional repressor nrdR 1420802 10579698 Trebr_1197 Treponema brennaborense DSM 12168 Transcriptional repressor nrdR YP_004439756.1 1420338 R 906968 CDS YP_004439757.1 332297835 10579699 complement(1421039..1421728) 1 NC_015500.1 KEGG: tde:TDE1649 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920087; hypothetical protein 1421728 10579699 Trebr_1198 Treponema brennaborense DSM 12168 hypothetical protein YP_004439757.1 1421039 R 906968 CDS YP_004439758.1 332297836 10579700 complement(1421719..1422495) 1 NC_015500.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE1650 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504920088; PFAM: ABC transporter; polyamine-transporting ATPase 1422495 10579700 Trebr_1199 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004439758.1 1421719 R 906968 CDS YP_004439759.1 332297837 10579701 complement(1422492..1423061) 1 NC_015500.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: tde:TDE1651 BioY family protein; PFAM: BioY protein; SPTR: BioY protein; IMG reference gene:2504920089; PFAM: BioY family; BioY protein 1423061 10579701 Trebr_1200 Treponema brennaborense DSM 12168 BioY protein YP_004439759.1 1422492 R 906968 CDS YP_004439760.1 332297838 10579702 complement(1423114..1424829) 1 NC_015500.1 COGs: COG0815 Apolipoprotein N-acyltransferase; HAMAP: Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: tde:TDE2299 apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase 2; TIGRFAM: Apolipoprotein N-acyltransferase; IMG reference gene:2504920090; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 1424829 10579702 Trebr_1201 Treponema brennaborense DSM 12168 apolipoprotein N-acyltransferase YP_004439760.1 1423114 R 906968 CDS YP_004439761.1 332297839 10579703 1424892..1426067 1 NC_015500.1 COGs: COG0153 Galactokinase; InterPro IPR019539:IPR013750; KEGG: tde:TDE2298 galactokinase, PFAM: Galactokinase galactose-binding domain; GHMP kinase, C-terminal; PRIAM: Galactokinase; SPTR: Galactokinase; IMG reference gene:2504920091; PFAM: Galactokinase galactose-binding signature; Galactokinase 1426067 10579703 Trebr_1202 Treponema brennaborense DSM 12168 Galactokinase YP_004439761.1 1424892 D 906968 CDS YP_004439762.1 332297840 10579704 1426105..1426842 1 NC_015500.1 COGs: COG0496 acid phosphatase; HAMAP: Multifunctional protein surE; InterPro IPR002828; KEGG: ssm:Spirs_3174 stationary-phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: 5'-nucleotidase surE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase; IMG reference gene:2504920092; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; multifunctional protein surE 1426842 10579704 Trebr_1203 Treponema brennaborense DSM 12168 multifunctional protein surE YP_004439762.1 1426105 D 906968 CDS YP_004439763.1 332297841 10579705 1426860..1427573 1 NC_015500.1 InterPro IPR019734:IPR001440:IPR013105; KEGG: tde:TDE2297 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; IMG reference gene:2504920093; PFAM: RNA polymerase I-associated factor PAF67; Tetratricopeptide repeat; hypothetical protein 1427573 10579705 Trebr_1204 Treponema brennaborense DSM 12168 hypothetical protein YP_004439763.1 1426860 D 906968 CDS YP_004439764.1 332297842 10579706 1427570..1429624 1 NC_015500.1 InterPro IPR001258; KEGG: tde:TDE2296 hypothetical protein; PFAM: NHL repeat; SPTR: lipoprotein; IMG reference gene:2504920094; PFAM: NHL repeat; NHL repeat containing protein 1429624 10579706 Trebr_1205 Treponema brennaborense DSM 12168 NHL repeat containing protein YP_004439764.1 1427570 D 906968 CDS YP_004439765.1 332297843 10579707 complement(1429657..1435674) 1 NC_015500.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; HAMAP: DNA polymerase IV; InterPro IPR001126; KEGG: tde:TDE0963 DNA polymerase IV; PFAM: DNA-repair protein, UmuC-like; PRIAM: DNA-directed DNA polymerase; SPTR: DNA polymerase IV; IMG reference gene:2504920095; PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family; DNA polymerase IV 1435674 10579707 Trebr_1206 Treponema brennaborense DSM 12168 DNA polymerase IV YP_004439765.1 1429657 R 906968 CDS YP_004439766.1 332297844 10579708 complement(1435671..1437698) 1 NC_015500.1 KEGG: tde:TDE0962 hypothetical protein; SPTR: membrane protein; IMG reference gene:2504920096; hypothetical protein 1437698 10579708 Trebr_1207 Treponema brennaborense DSM 12168 hypothetical protein YP_004439766.1 1435671 R 906968 CDS YP_004439767.1 332297845 10579709 1437778..1438944 1 NC_015500.1 KEGG: tde:TDE1128 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920097; hypothetical protein 1438944 10579709 Trebr_1208 Treponema brennaborense DSM 12168 hypothetical protein YP_004439767.1 1437778 D 906968 CDS YP_004439768.1 332297846 10579710 1438951..1439652 1 NC_015500.1 IMG reference gene:2504920098; hypothetical protein 1439652 10579710 Trebr_1209 Treponema brennaborense DSM 12168 hypothetical protein YP_004439768.1 1438951 D 906968 CDS YP_004439769.1 332297847 10579711 1439655..1440377 1 NC_015500.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; HAMAP: tRNA (guanine-N(7)-)-methyltransferase; InterPro IPR003358; KEGG: tde:TDE1130 methyltransferase, PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N-7) methyltransferase; IMG reference gene:2504920099; PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase 1440377 10579711 Trebr_1210 Treponema brennaborense DSM 12168 tRNA (guanine-N(7)-)-methyltransferase YP_004439769.1 1439655 D 906968 CDS YP_004439770.1 332297848 10579712 1440379..1442319 1 NC_015500.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); HAMAP: DNA ligase; InterProIPR001679:IPR013840:IPR001357:IPR013839:IPR 004150; KEGG: tde:TDE1538 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase, adenylation; NAD-dependent DNA ligase, OB-fold; BRCT; SMART: NAD-dependent DNA ligase, N-terminal; BRCT; SPTR: DNA ligase, NAD-dependent; TIGRFAM: NAD-dependent DNA ligase; IMG reference gene:2504920100; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent; DNA ligase 1442319 10579712 Trebr_1211 Treponema brennaborense DSM 12168 DNA ligase YP_004439770.1 1440379 D 906968 CDS YP_004439771.1 332297849 10579713 1442319..1442939 1 NC_015500.1 IMG reference gene:2504920101; hypothetical protein 1442939 10579713 Trebr_1212 Treponema brennaborense DSM 12168 hypothetical protein YP_004439771.1 1442319 D 906968 CDS YP_004439772.1 332297850 10579714 complement(1442916..1443926) 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tde:TDE2189 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2504920102; PFAM: Peptidase family M23; peptidase M23 1443926 10579714 Trebr_1213 Treponema brennaborense DSM 12168 peptidase M23 YP_004439772.1 1442916 R 906968 CDS YP_004439773.1 332297851 10579716 1444368..1444757 1 NC_015500.1 KEGG: mtt:Ftrac_0842 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920104; PFAM: Protein of unknown function (DUF2721); hypothetical protein 1444757 10579716 Trebr_1214 Treponema brennaborense DSM 12168 hypothetical protein YP_004439773.1 1444368 D 906968 CDS YP_004439774.1 332297852 10579717 1444853..1445062 1 NC_015500.1 InterPro IPR007167; KEGG: csh:Closa_0962 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SPTR: uncharacterized protein; IMG reference gene:2504920105; PFAM: FeoA domain; FeoA family protein 1445062 10579717 Trebr_1215 Treponema brennaborense DSM 12168 FeoA family protein YP_004439774.1 1444853 D 906968 CDS YP_004439775.1 332297853 10579718 1445076..1445294 1 NC_015500.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: eel:EUBELI_00573 ferrous iron transport protein A; PFAM: Ferrous iron transporter, FeoA subunit; SPTR: uncharacterized protein; IMG reference gene:2504920106; PFAM: FeoA domain; FeoA family protein 1445294 10579718 Trebr_1216 Treponema brennaborense DSM 12168 FeoA family protein YP_004439775.1 1445076 D 906968 CDS YP_004439776.1 332297854 10579719 1445345..1447489 1 NC_015500.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225:IPR003373:IPR002917:IPR011619:IPR 011642:IPR011640; KEGG: csh:Closa_0964 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B, N-terminal; GTP-binding protein, HSR1-related; Nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; IMG reference gene:2504920107; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain; ferrous iron transport protein B 1447489 10579719 Trebr_1217 Treponema brennaborense DSM 12168 ferrous iron transport protein B YP_004439776.1 1445345 D 906968 CDS YP_004439777.1 332297855 10579720 1447559..1447717 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504920108; hypothetical protein 1447717 10579720 Trebr_1218 Treponema brennaborense DSM 12168 hypothetical protein YP_004439777.1 1447559 D 906968 CDS YP_004439778.1 332297856 10579721 1447802..1448380 1 NC_015500.1 KEGG: csh:Closa_2904 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920109; hypothetical protein 1448380 10579721 Trebr_1219 Treponema brennaborense DSM 12168 hypothetical protein YP_004439778.1 1447802 D 906968 CDS YP_004439779.1 332297857 10579722 1448392..1448820 1 NC_015500.1 COGs: COG0716 Flavodoxins; InterPro IPR010087:IPR008254; KEGG: ckr:CKR_1900 flavodoxin; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin, short chain; TIGRFAM: Flavodoxin, short chain; IMG reference gene:2504920110; PFAM: Flavodoxin; TIGRFAM: flavodoxin, short chain; flavodoxin 1448820 10579722 Trebr_1220 Treponema brennaborense DSM 12168 flavodoxin YP_004439779.1 1448392 D 906968 CDS YP_004439780.1 332297858 10579723 1448996..1450105 1 NC_015500.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: mla:Mlab_1044 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504920111; PFAM: Periplasmic binding protein; ABC transporter substrate-binding protein 1450105 10579723 Trebr_1221 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004439780.1 1448996 D 906968 CDS YP_004439781.1 332297859 10579724 1450118..1451011 1 NC_015500.1 COGs: COG1348 Nitrogenase subunit NifH (ATPase); InterPro IPR000392; KEGG: aoe:Clos_0309 nitrogenase; PFAM: Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; PRIAM: Nitrogenase; SPTR: Nitrogenase iron protein (Nitrogenase component II)(Nitrogenase Fe protein) (Nitrogenase reductase); IMG reference gene:2504920112; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein; nitrogenase 1451011 10579724 Trebr_1222 Treponema brennaborense DSM 12168 nitrogenase YP_004439781.1 1450118 D 906968 CDS YP_004439782.1 332297860 10579725 1451008..1452282 1 NC_015500.1 KEGG: rpx:Rpdx1_2419 nitrogenase molybdenum-iron protein alpha and beta chains-like protein; SPTR: uncharacterized protein; IMG reference gene:2504920113; PFAM: Nitrogenase component 1 type Oxidoreductase; nitrogenase molybdenum-iron protein alpha and beta chains-like protein 1452282 10579725 Trebr_1223 Treponema brennaborense DSM 12168 nitrogenase molybdenum-iron protein alpha and beta chains-like protein YP_004439782.1 1451008 D 906968 CDS YP_004439783.1 332297861 10579726 1452279..1453496 1 NC_015500.1 COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510; KEGG: dhd:Dhaf_1540 hypothetical protein; PFAM: Nitrogenase/oxidoreductase, component 1; SPTR: Oxidoreductase, nitrogenase component 1 family protein; IMG reference gene:2504920114; PFAM: Nitrogenase component 1 type Oxidoreductase; oxidoreductase/nitrogenase component 1 1453496 10579726 Trebr_1224 Treponema brennaborense DSM 12168 oxidoreductase/nitrogenase component 1 YP_004439783.1 1452279 D 906968 CDS YP_004439784.1 332297862 10579727 1453507..1454613 1 NC_015500.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: mla:Mlab_1044 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504920115; PFAM: Periplasmic binding protein; ABC transporter substrate-binding protein 1454613 10579727 Trebr_1225 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004439784.1 1453507 D 906968 CDS YP_004439785.1 332297863 10579728 1454615..1455634 1 NC_015500.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: mla:Mlab_1043 hypothetical protein; PFAM: Bacterial transport system permease protein; SPTR: Iron(III) dicitrate transport ATP-binding protein fecE; IMG reference gene:2504920116; PFAM: FecCD transport family; ABC transporter permease 1455634 10579728 Trebr_1226 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439785.1 1454615 D 906968 CDS YP_004439786.1 332297864 10579729 1455631..1456416 1 NC_015500.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: mla:Mlab_1042 hypothetical protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Hemin import ATP-binding protein HmuV; IMG reference gene:2504920117; PFAM: ABC transporter; Phosphonate-transporting ATPase 1456416 10579729 Trebr_1227 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439786.1 1455631 D 906968 CDS YP_004439787.1 332297865 10579730 1456548..1458104 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: ssm:Spirs_2649 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2504920118; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1458104 10579730 Trebr_1228 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004439787.1 1456548 D 906968 CDS YP_004439788.1 332297866 10579731 1458079..1459128 1 NC_015500.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003594:IPR010559; KEGG: ssm:Spirs_2648 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504920119; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 1459128 10579731 Trebr_1229 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004439788.1 1458079 D 906968 CDS YP_004439789.1 332297867 10579732 1459125..1460579 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; KEGG: ssm:Spirs_2647 monosaccharide-transporting ATPase; SPTR: Monosaccharide-transporting ATPase; IMG reference gene:2504920120; monosaccharide-transporting ATPase 1460579 10579732 Trebr_1230 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439789.1 1459125 D 906968 CDS YP_004439790.1 332297868 10579733 1460679..1462184 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ssm:Spirs_2646 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-); IMG reference gene:2504920121; PFAM: ABC transporter; monosaccharide-transporting ATPase 1462184 10579733 Trebr_1231 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439790.1 1460679 D 906968 CDS YP_004439791.1 332297869 10579734 1462187..1463191 1 NC_015500.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: csh:Closa_1913 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504920122; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 1463191 10579734 Trebr_1232 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439791.1 1462187 D 906968 CDS YP_004439792.1 332297870 10579735 1463316..1464233 1 NC_015500.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: csh:Closa_1914 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; IMG reference gene:2504920123; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1464233 10579735 Trebr_1233 Treponema brennaborense DSM 12168 periplasmic binding protein/LacI transcriptional regulator YP_004439792.1 1463316 D 906968 CDS YP_004439793.1 332297871 10579736 1464740..1466572 1 NC_015500.1 InterPro IPR013378; PFAM: Listeria/Bacterioides repeat; SPTR: lipoprotein; TIGRFAM: Listeria/Bacterioides repeat; IMG reference gene:2504920124; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); TIGRFAM: Listeria/Bacterioides repeat; cell wall/surface repeat protein 1466572 10579736 Trebr_1234 Treponema brennaborense DSM 12168 cell wall/surface repeat protein YP_004439793.1 1464740 D 906968 CDS YP_004439794.1 332297872 10579737 1466589..1467905 1 NC_015500.1 IMG reference gene:2504920125; hypothetical protein 1467905 10579737 Trebr_1235 Treponema brennaborense DSM 12168 hypothetical protein YP_004439794.1 1466589 D 906968 CDS YP_004439795.1 332297873 10579738 1468030..1468890 1 NC_015500.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: cbt:CLH_2952 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; IMG reference gene:2504920126; PFAM: Pyridine nucleotide-disulphide oxidoreductase; thioredoxin-disulfide reductase 1468890 10579738 Trebr_1236 Treponema brennaborense DSM 12168 thioredoxin-disulfide reductase YP_004439795.1 1468030 D 906968 CDS YP_004439796.1 332297874 10579739 complement(1468926..1470314) 1 NC_015500.1 KEGG: fsu:Fisuc_0005 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920127; hypothetical protein 1470314 10579739 Trebr_1237 Treponema brennaborense DSM 12168 hypothetical protein YP_004439796.1 1468926 R 906968 CDS YP_004439797.1 332297875 10579740 complement(1470323..1471159) 1 NC_015500.1 KEGG: fsu:Fisuc_0003 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920128; PFAM: Protein of unknown function (DUF1329); hypothetical protein 1471159 10579740 Trebr_1238 Treponema brennaborense DSM 12168 hypothetical protein YP_004439797.1 1470323 R 906968 CDS YP_004439798.1 332297876 10579741 complement(1471189..1473582) 1 NC_015500.1 COGs: COG1033 exporter of the RND superfamily protein; KEGG: fsu:Fisuc_1684 exporter of the RND superfamily protein-like protein; SPTR: Exporter of the RND superfamily protein-like protein; IMG reference gene:2504920129; PFAM: MMPL family; AcrB/AcrD/AcrF family; exporter of the RND superfamily protein-like protein 1473582 10579741 Trebr_1239 Treponema brennaborense DSM 12168 exporter of the RND superfamily protein-like protein YP_004439798.1 1471189 R 906968 CDS YP_004439799.1 332297877 10579742 1473779..1474435 1 NC_015500.1 InterPro IPR001647; KEGG: tde:TDE1601 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: uncharacterized protein; IMG reference gene:2504920130; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1474435 10579742 Trebr_1240 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004439799.1 1473779 D 906968 CDS YP_004439800.1 332297878 10579743 1474453..1475232 1 NC_015500.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cpy:Cphy_0713 zinc/iron permease; PFAM: Zinc/iron permease; SPTR: Zinc/iron permease; IMG reference gene:2504920131; PFAM: ZIP Zinc transporter; zinc/iron permease 1475232 10579743 Trebr_1241 Treponema brennaborense DSM 12168 zinc/iron permease YP_004439800.1 1474453 D 906968 CDS YP_004439801.1 332297879 10579744 1475249..1476151 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847; KEGG: gym:GYMC10_4684 transcriptional regulator, LysR family; PFAM: HTH transcriptional regulator, LysR; SPTR: Regulatory protein; IMG reference gene:2504920132; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; LysR family transcriptional regulator 1476151 10579744 Trebr_1242 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004439801.1 1475249 D 906968 CDS YP_004439802.1 332297880 10579745 1476243..1478552 1 NC_015500.1 COGs: COG0620 Methionine synthase II (cobalamin-independent); HAMAP:5-methyltetrahydropteroyltriglutamate--homocy steineS-methyltransferase; InterPro IPR006276:IPR013215:IPR002629; KEGG: lba:Lebu_0514 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal; PRIAM:5-methyltetrahydropteroyltriglutamate--homocy steineS-methyltransferase; SPTR: uncharacterized protein; TIGRFAM:5-methyltetrahydropteroyltriglutamate--homo cysteineS-methyltransferase; IMG reference gene:2504920133; PFAM: Cobalamin-independent synthase, Catalytic domain; Cobalamin-independent synthase, N-terminal domain; TIGRFAM: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1478552 10579745 Trebr_1243 Treponema brennaborense DSM 12168 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_004439802.1 1476243 D 906968 CDS YP_004439803.1 332297881 10579746 1478549..1479436 1 NC_015500.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171:IPR004620; KEGG: ere:EUBREC_2200 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; IMG reference gene:2504920134; PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; 5,10-methylenetetrahydrofolate reductase 1479436 10579746 Trebr_1244 Treponema brennaborense DSM 12168 5,10-methylenetetrahydrofolate reductase YP_004439803.1 1478549 D 906968 CDS YP_004439804.1 332297882 10579747 1479593..1480021 1 NC_015500.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: shi:Shel_19320 Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric-uptake regulator; SPTR: uncharacterized protein; IMG reference gene:2504920135; PFAM: Ferric uptake regulator family; ferric uptake regulator, Fur family 1480021 10579747 Trebr_1245 Treponema brennaborense DSM 12168 ferric uptake regulator, Fur family YP_004439804.1 1479593 D 906968 CDS YP_004439805.1 332297883 10579748 1480018..1480299 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504920136; hypothetical protein 1480299 10579748 Trebr_1246 Treponema brennaborense DSM 12168 hypothetical protein YP_004439805.1 1480018 D 906968 CDS YP_004439806.1 332297884 10579749 1480362..1481378 1 NC_015500.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: elm:ELI_0565 periplasmic solute binding protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: uncharacterized protein; IMG reference gene:2504920137; PFAM: Periplasmic solute binding protein family; heavy metal ABC transporter substrate-binding protein 1481378 10579749 Trebr_1247 Treponema brennaborense DSM 12168 heavy metal ABC transporter substrate-binding protein YP_004439806.1 1480362 D 906968 CDS YP_004439807.1 332297885 10579750 1481399..1482124 1 NC_015500.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: elm:ELI_0566 hypothetical protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; IMG reference gene:2504920138; PFAM: ABC transporter; Phosphonate-transporting ATPase 1482124 10579750 Trebr_1248 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004439807.1 1481399 D 906968 CDS YP_004439808.1 332297886 10579751 1482121..1482966 1 NC_015500.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: elm:ELI_0567 ABC-3 protein; PFAM: ABC-3; SPTR: uncharacterized protein; IMG reference gene:2504920139; PFAM: ABC 3 transport family; ABC transporter permease 1482966 10579751 Trebr_1249 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439808.1 1482121 D 906968 CDS YP_004439809.1 332297887 10579752 1482963..1483682 1 NC_015500.1 KEGG: brm:Bmur_0595 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2504920140; hypothetical protein 1483682 10579752 Trebr_1250 Treponema brennaborense DSM 12168 hypothetical protein YP_004439809.1 1482963 D 906968 CDS YP_004439810.1 332297888 10579753 1483804..1483950 1 NC_015500.1 IMG reference gene:2504920141; hypothetical protein 1483950 10579753 Trebr_1251 Treponema brennaborense DSM 12168 hypothetical protein YP_004439810.1 1483804 D 906968 CDS YP_004439811.1 332297889 10579754 1483982..1484452 1 NC_015500.1 COGs: COG0756 dUTPase; HAMAP: Deoxyuridine 5'-triphosphate nucleotidohydrolase; InterPro IPR008180:IPR008181; KEGG: cak:Caul_5069 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: DeoxyUTP pyrophosphatase domain; PRIAM: dUTP diphosphatase; SPTR: Deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: DeoxyUTP pyrophosphatase domain, subfamily 1,; manually curated; IMG reference gene:2504920142; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); deoxyuridine 5'-triphosphate nucleotidohydrolase 1484452 10579754 Trebr_1252 Treponema brennaborense DSM 12168 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_004439811.1 1483982 D 906968 CDS YP_004439812.1 332297890 10579755 1484449..1485594 1 NC_015500.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1043 hypothetical protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Membrane protein, ; IMG reference gene:2504920143; PFAM: Predicted permease YjgP/YjgQ family; YjgP/YjgQ family permease 1485594 10579755 Trebr_1253 Treponema brennaborense DSM 12168 YjgP/YjgQ family permease YP_004439812.1 1484449 D 906968 CDS YP_004439813.1 332297891 10579756 1485561..1486661 1 NC_015500.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1044 hypothetical protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Membrane protein, ; IMG reference gene:2504920144; PFAM: Predicted permease YjgP/YjgQ family; YjgP/YjgQ family permease 1486661 10579756 Trebr_1254 Treponema brennaborense DSM 12168 YjgP/YjgQ family permease YP_004439813.1 1485561 D 906968 CDS YP_004439814.1 332297892 10579757 1486754..1487902 1 NC_015500.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; HAMAP: Queuine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: tde:TDE0438 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: Queuine tRNA-ribosyltransferase; Queuine/other tRNA-ribosyltransferase; IMG reference gene:2504920145; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming; queuine tRNA-ribosyltransferase 1487902 10579757 Trebr_1255 Treponema brennaborense DSM 12168 queuine tRNA-ribosyltransferase YP_004439814.1 1486754 D 906968 CDS YP_004439815.1 332297893 10579758 1487899..1489305 1 NC_015500.1 InterPro IPR004155; KEGG: tde:TDE0437 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT-like repeat; SPTR: PBS lyase HEAT-like repeat domain protein; IMG reference gene:2504920146; PFAM: PBS lyase HEAT-like repeat; PBS lyase HEAT domain-containing protein repeat-containing protein 1489305 10579758 Trebr_1256 Treponema brennaborense DSM 12168 PBS lyase HEAT domain-containing protein repeat-containing protein YP_004439815.1 1487899 D 906968 CDS YP_004439816.1 332297894 10579759 1489351..1489836 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tpp:TPASS_0439 purine-binding chemotaxis protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Purine-binding chemotaxis protein; IMG reference gene:2504920147; PFAM: CheW-like domain; CheW protein 1489836 10579759 Trebr_1257 Treponema brennaborense DSM 12168 CheW protein YP_004439816.1 1489351 D 906968 CDS YP_004439817.1 332297895 10579760 1489838..1490890 1 NC_015500.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tde:TDE1590 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Aminotransferase, DegT/DnrJ/EryC1/StrS family; IMG reference gene:2504920148; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase 1490890 10579760 Trebr_1258 Treponema brennaborense DSM 12168 DegT/DnrJ/EryC1/StrS aminotransferase YP_004439817.1 1489838 D 906968 CDS YP_004439818.1 332297896 10579761 1490916..1491758 1 NC_015500.1 COGs: COG0061 sugar kinase; HAMAP: inorganic polyphosphate/ATP-NAD kinase; InterPro IPR002504; KEGG: tde:TDE1591 inorganic polyphosphate/ATP-NAD kinase, PFAM: ATP-NAD/AcoX kinase; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase; IMG reference gene:2504920149; PFAM: ATP-NAD kinase; inorganic polyphosphate/ATP-NAD kinase 1491758 10579761 Trebr_1259 Treponema brennaborense DSM 12168 inorganic polyphosphate/ATP-NAD kinase YP_004439818.1 1490916 D 906968 CDS YP_004439819.1 332297897 10579762 1491751..1493499 1 NC_015500.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003593:IPR003395:IPR004604; KEGG: tde:TDE1301 DNA repair protein RecN; PFAM: RecF/RecN/SMC protein, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein RecN; TIGRFAM: DNA recombination/repair protein RecN; IMG reference gene:2504920150; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN; DNA repair protein RecN 1493499 10579762 Trebr_1260 Treponema brennaborense DSM 12168 DNA repair protein RecN YP_004439819.1 1491751 D 906968 CDS YP_004439820.1 332297898 10579763 1493481..1494284 1 NC_015500.1 KEGG: tde:TDE1300 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920151; hypothetical protein 1494284 10579763 Trebr_1261 Treponema brennaborense DSM 12168 hypothetical protein YP_004439820.1 1493481 D 906968 CDS YP_004439821.1 332297899 10579764 1494436..1495539 1 NC_015500.1 COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: sta:STHERM_c17750 membrane lipoprotein TmpC precursor; PFAM: Basic membrane lipoprotein; SPTR: uncharacterized protein; IMG reference gene:2504920152; PFAM: Basic membrane protein; basic membrane lipoprotein 1495539 10579764 Trebr_1262 Treponema brennaborense DSM 12168 basic membrane lipoprotein YP_004439821.1 1494436 D 906968 CDS YP_004439822.1 332297900 10579765 1495661..1497199 1 NC_015500.1 COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: aoe:Clos_0964 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504920153; PFAM: ABC transporter; monosaccharide-transporting ATPase 1497199 10579765 Trebr_1263 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004439822.1 1495661 D 906968 CDS YP_004439823.1 332297901 10579766 1497199..1498344 1 NC_015500.1 COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c17730 permease; PFAM: Bacterial inner-membrane translocator; SPTR: Carbohydrate uptake 2 (CUT2) family, permease protein; IMG reference gene:2504920154; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 1498344 10579766 Trebr_1264 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439823.1 1497199 D 906968 CDS YP_004439824.1 332297902 10579767 1498346..1499251 1 NC_015500.1 COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: amt:Amet_3583 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504920155; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 1499251 10579767 Trebr_1265 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439824.1 1498346 D 906968 CDS YP_004439825.1 332297903 10579768 1499356..1500468 1 NC_015500.1 COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: ssm:Spirs_0579 ABC transporter related protein; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Glycerol-3-phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Multiple sugar-binding transport ATP-binding protein MsmK; IMG reference gene:2504920156; PFAM: ABC transporter; TOBE domain; Glycerol-3-phosphate-transporting ATPase 1500468 10579768 Trebr_1266 Treponema brennaborense DSM 12168 Glycerol-3-phosphate-transporting ATPase YP_004439825.1 1499356 D 906968 CDS YP_004439826.1 332297904 10579769 complement(1500609..1502528) 1 NC_015500.1 COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: tde:TDE1371 RNB-like family protein; PFAM: Ribonuclease II/R; SPTR: Exoribonuclease II; IMG reference gene:2504920157; PFAM: RNB domain; ribonuclease II 1502528 10579769 Trebr_1267 Treponema brennaborense DSM 12168 ribonuclease II YP_004439826.1 1500609 R 906968 CDS YP_004439827.1 332297905 10579770 complement(1502638..1504206) 1 NC_015500.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466:IPR005180; KEGG: bfr:BF3534 peptidase; PFAM: Beta-lactamase-related; Protein of unknown function DUF302; SPTR: uncharacterized protein; IMG reference gene:2504920158; PFAM: Domain of unknown function DUF302; Beta-lactamase; beta-lactamase 1504206 10579770 Trebr_1268 Treponema brennaborense DSM 12168 beta-lactamase YP_004439827.1 1502638 R 906968 CDS YP_004439828.1 332297906 10579773 1505131..1505556 1 NC_015500.1 InterPro IPR000045; KEGG: syn:slr1120 type 4 prepilin peptidase; PFAM: Peptidase A24A, prepilin type IV; SPTR: uncharacterized protein; IMG reference gene:2504920161; PFAM: Type IV leader peptidase family; peptidase A24A prepilin type IV 1505556 10579773 Trebr_1269 Treponema brennaborense DSM 12168 peptidase A24A prepilin type IV YP_004439828.1 1505131 D 906968 CDS YP_004439829.1 332297907 10579775 1506204..1507103 1 NC_015500.1 IMG reference gene:2504920163; hypothetical protein 1507103 10579775 Trebr_1271 Treponema brennaborense DSM 12168 hypothetical protein YP_004439829.1 1506204 D 906968 CDS YP_004439830.1 332297908 10579776 1507382..1508359 1 NC_015500.1 IMG reference gene:2504920164; hypothetical protein 1508359 10579776 Trebr_1272 Treponema brennaborense DSM 12168 hypothetical protein YP_004439830.1 1507382 D 906968 CDS YP_004439831.1 332297909 10579777 1508359..1509558 1 NC_015500.1 KEGG: sta:STHERM_c19940 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920165; hypothetical protein 1509558 10579777 Trebr_1273 Treponema brennaborense DSM 12168 hypothetical protein YP_004439831.1 1508359 D 906968 CDS YP_004439832.1 332297910 10579778 1509678..1510208 1 NC_015500.1 InterPro IPR006674; KEGG: mla:Mlab_1526 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: phosphohydrolase; IMG reference gene:2504920166; metal-dependent phosphohydrolase HD sub domain-containing protein 1510208 10579778 Trebr_1274 Treponema brennaborense DSM 12168 metal-dependent phosphohydrolase HD sub domain-containing protein YP_004439832.1 1509678 D 906968 CDS YP_004439833.1 332297911 10579779 complement(1510157..1511524) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: has:Halsa_1701 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504920167; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 1511524 10579779 Trebr_1275 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004439833.1 1510157 R 906968 CDS YP_004439834.1 332297912 10579780 complement(1511541..1512491) 1 NC_015500.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cdl:CDR20291_1482 sugar metabolism repressor; PFAM: ROK; SPTR: ROK family protein; IMG reference gene:2504920168; PFAM: ROK family; ROK family protein 1512491 10579780 Trebr_1276 Treponema brennaborense DSM 12168 ROK family protein YP_004439834.1 1511541 R 906968 CDS YP_004439835.1 332297913 10579781 1512635..1513708 1 NC_015500.1 COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: tde:TDE0069 hypothetical protein; PFAM: Radical SAM; PRIAM: Lysine 2,3-aminomutase; SPTR: uncharacterized protein; TIGRFAM: Protein of unknown function DUF160; IMG reference gene:2504920169; PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; lysine 2,3-aminomutase YodO family protein 1513708 10579781 Trebr_1277 Treponema brennaborense DSM 12168 lysine 2,3-aminomutase YodO family protein YP_004439835.1 1512635 D 906968 CDS YP_004439836.1 332297914 10579782 1513928..1514737 1 NC_015500.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR009042:IPR007627:IPR007624:IPR007630:IPR 014284; KEGG: ssm:Spirs_1794 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504920170; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 1514737 10579782 Trebr_1278 Treponema brennaborense DSM 12168 RpoD subfamily RNA polymerase sigma-70 subunit YP_004439836.1 1513928 D 906968 CDS YP_004439837.1 332297915 10579783 1514818..1516083 1 NC_015500.1 COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: brm:Bmur_1049 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; IMG reference gene:2504920171; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; argininosuccinate synthase 1516083 10579783 Trebr_1279 Treponema brennaborense DSM 12168 argininosuccinate synthase YP_004439837.1 1514818 D 906968 CDS YP_004439838.1 332297916 10579784 1516181..1518688 1 NC_015500.1 COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: aspartate kinase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; SPTR: Aspartokinase i-homoserine dehydrogenase i; TIGRFAM: Aspartate kinase region; IMG reference gene:2504920172; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase; aspartate kinase 1518688 10579784 Trebr_1280 Treponema brennaborense DSM 12168 aspartate kinase YP_004439838.1 1516181 D 906968 CDS YP_004439839.1 332297917 10579785 1518726..1520711 1 NC_015500.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR001086:IPR006268; KEGG: sta:STHERM_c18910 hypothetical protein; PFAM: DAHP synthetase I/KDSA; Prephenate dehydratase; PRIAM: 3-deoxy-7-phosphoheptulonate synthase., Prephenate dehydratase; SPTR: uncharacterized protein; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504920173; PFAM: Prephenate dehydratase; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; phospho-2-dehydro-3-deoxyheptonate aldolase 1520711 10579785 Trebr_1281 Treponema brennaborense DSM 12168 phospho-2-dehydro-3-deoxyheptonate aldolase YP_004439839.1 1518726 D 906968 CDS YP_004439840.1 332297918 10579786 1520712..1521203 1 NC_015500.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: cob:COB47_0453 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504920174; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit; acetolactate synthase small subunit 1521203 10579786 Trebr_1282 Treponema brennaborense DSM 12168 acetolactate synthase small subunit YP_004439840.1 1520712 D 906968 CDS YP_004439841.1 332297919 10579787 1521207..1522364 1 NC_015500.1 InterPro IPR011701; KEGG: rca:Rcas_0526 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: MFS_1, major facilitator family; IMG reference gene:2504920175; PFAM: Nucleoside H+ symporter; major facilitator superfamily protein 1522364 10579787 Trebr_1283 Treponema brennaborense DSM 12168 major facilitator superfamily protein YP_004439841.1 1521207 D 906968 CDS YP_004439842.1 332297920 10579788 1522358..1523098 1 NC_015500.1 COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: ssm:Spirs_0939 protein of unknown function DUF554; PFAM: Protein of unknown function DUF554; SPTR: uncharacterized protein; IMG reference gene:2504920176; PFAM: Protein of unknown function (DUF554); hypothetical protein 1523098 10579788 Trebr_1284 Treponema brennaborense DSM 12168 hypothetical protein YP_004439842.1 1522358 D 906968 CDS YP_004439843.1 332297921 10579789 complement(1523150..1524502) 1 NC_015500.1 COGs: COG1415 conserved hypothetical protein; InterPro IPR008482; KEGG: sus:Acid_7730 hypothetical protein; PFAM: Protein of unknown function DUF763; SPTR: uncharacterized protein; IMG reference gene:2504920177; PFAM: Protein of unknown function (DUF763); hypothetical protein 1524502 10579789 Trebr_1285 Treponema brennaborense DSM 12168 hypothetical protein YP_004439843.1 1523150 R 906968 CDS YP_004439844.1 332297922 10579790 1524734..1526566 1 NC_015500.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: ssm:Spirs_3800 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent RNA helicase DbpA; IMG reference gene:2504920178; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase domain protein 1526566 10579790 Trebr_1286 Treponema brennaborense DSM 12168 DEAD/DEAH box helicase domain protein YP_004439844.1 1524734 D 906968 CDS YP_004439845.1 332297923 10579791 1526573..1528210 1 NC_015500.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: tde:TDE1592 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504920179; PFAM: ABC transporter; ABC transporter 1528210 10579791 Trebr_1287 Treponema brennaborense DSM 12168 ABC transporter YP_004439845.1 1526573 D 906968 CDS YP_004439846.1 332297924 10579792 1528388..1530442 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: ssm:Spirs_3480 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor; IMG reference gene:2504920180; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1530442 10579792 Trebr_1288 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004439846.1 1528388 D 906968 CDS YP_004439847.1 332297925 10579793 complement(1530467..1532140) 1 NC_015500.1 KEGG: hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920181; hypothetical protein 1532140 10579793 Trebr_1289 Treponema brennaborense DSM 12168 hypothetical protein YP_004439847.1 1530467 R 906968 CDS YP_004439848.1 332297926 10579794 1532281..1533207 1 NC_015500.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; HAMAP: Ribonuclease Z; InterPro IPR013471; KEGG: tde:TDE1951 ribonuclease Z; SPTR: Ribonuclease Z; TIGRFAM: Ribonuclease Z; manually curated; IMG reference gene:2504920182; PFAM: Metallo-beta-lactamase superfamily; TIGRFAM: ribonuclease Z; Ribonuclease Z 1533207 10579794 Trebr_1290 Treponema brennaborense DSM 12168 Ribonuclease Z YP_004439848.1 1532281 D 906968 CDS YP_004439849.1 332297927 10579795 1533261..1534016 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: npu:Npun_F0551 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein, ; IMG reference gene:2504920183; PFAM: ABC transporter; sulfate-transporting ATPase 1534016 10579795 Trebr_1291 Treponema brennaborense DSM 12168 sulfate-transporting ATPase YP_004439849.1 1533261 D 906968 CDS YP_004439850.1 332297928 10579796 1534009..1534767 1 NC_015500.1 KEGG: pau:PA14_11610 ABC transporter permease; SPTR: Possible ABC transporter permease component; IMG reference gene:2504920184; ABC transporter permease 1534767 10579796 Trebr_1292 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439850.1 1534009 D 906968 CDS YP_004439851.1 332297929 10579797 1534764..1536407 1 NC_015500.1 COGs: COG3225 ABC-type uncharacterized transport system involved in gliding motility auxiliary component; InterPro IPR019196; KEGG: tde:TDE2112 hypothetical protein; PFAM: ABC-type uncharacterised transport system; SPTR: uncharacterized protein; IMG reference gene:2504920185; PFAM: ABC-type uncharacterized transport system; ABC transporter 1536407 10579797 Trebr_1293 Treponema brennaborense DSM 12168 ABC transporter YP_004439851.1 1534764 D 906968 CDS YP_004439852.1 332297930 10579798 1536400..1537401 1 NC_015500.1 IMG reference gene:2504920186; hypothetical protein 1537401 10579798 Trebr_1294 Treponema brennaborense DSM 12168 hypothetical protein YP_004439852.1 1536400 D 906968 CDS YP_004439853.1 332297931 10579799 complement(1537388..1538038) 1 NC_015500.1 InterPro IPR003675; KEGG: tde:TDE1317 hypothetical protein; PFAM: Abortive infection protein; SPTR: Membrane protein, ; IMG reference gene:2504920187; PFAM: CAAX amino terminal protease family; Abortive infection protein 1538038 10579799 Trebr_1295 Treponema brennaborense DSM 12168 Abortive infection protein YP_004439853.1 1537388 R 906968 CDS YP_004439854.1 332297932 10579800 1538073..1539182 1 NC_015500.1 InterPro IPR009875; KEGG: ssm:Spirs_1505 type IV pilus assembly PilZ; PFAM: Type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; IMG reference gene:2504920188; PFAM: PilZ domain; type IV pilus assembly PilZ 1539182 10579800 Trebr_1296 Treponema brennaborense DSM 12168 type IV pilus assembly PilZ YP_004439854.1 1538073 D 906968 CDS YP_004439855.1 332297933 10579801 1539217..1540416 1 NC_015500.1 KEGG: ssm:Spirs_1506 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920189; hypothetical protein 1540416 10579801 Trebr_1297 Treponema brennaborense DSM 12168 hypothetical protein YP_004439855.1 1539217 D 906968 CDS YP_004439856.1 332297934 10579802 1540410..1541741 1 NC_015500.1 COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: tde:TDE1320 ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein; IMG reference gene:2504920190; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; ComEC/Rec2-like protein 1541741 10579802 Trebr_1298 Treponema brennaborense DSM 12168 ComEC/Rec2-like protein YP_004439856.1 1540410 D 906968 CDS YP_004439857.1 332297935 10579803 1541741..1542625 1 NC_015500.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); HAMAP: Ribosomal RNA adenine dimethylase; InterPro IPR020598:IPR011530:IPR001737; KEGG: tde:TDE1080 dimethyladenosine transferase; PFAM: Ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase, N-terminal; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: Ribosomal RNA adenine dimethylase; IMG reference gene:2504920191; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase; ribosomal RNA small subunit methyltransferase A 1542625 10579803 Trebr_1299 Treponema brennaborense DSM 12168 ribosomal RNA small subunit methyltransferase A YP_004439857.1 1541741 D 906968 CDS YP_004439858.1 332297936 10579804 1542630..1543331 1 NC_015500.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: sta:STHERM_c17100 pyridoxal 5'-phosphate-dependent enzyme; PFAM: Alanine racemase, N-terminal; SPTR: Predicted pyridoxal 5'-phosphate-dependent enzyme; TIGRFAM: pyridoxal phosphate-dependent enzyme, YBL036C type; IMG reference gene:2504920192; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family; hypothetical protein 1543331 10579804 Trebr_1300 Treponema brennaborense DSM 12168 hypothetical protein YP_004439858.1 1542630 D 906968 CDS YP_004439859.1 332297937 10579805 1543328..1543867 1 NC_015500.1 KEGG: tde:TDE1081 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920193; hypothetical protein 1543867 10579805 Trebr_1301 Treponema brennaborense DSM 12168 hypothetical protein YP_004439859.1 1543328 D 906968 CDS YP_004439860.1 332297938 10579806 1543867..1544823 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145:IPR006225; KEGG: sta:STHERM_c17080 ribosomal large subunit pseudouridine synthase D; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Ribosomal large subunit pseudouridine synthase D; TIGRFAM: Pseudouridine synthase, RluC/RluD; IMG reference gene:2504920194; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; RluA family pseudouridine synthase 1544823 10579806 Trebr_1302 Treponema brennaborense DSM 12168 RluA family pseudouridine synthase YP_004439860.1 1543867 D 906968 CDS YP_004439861.1 332297939 10579807 1544805..1545602 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: tde:TDE1083 RNA pseudouridylate synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; IMG reference gene:2504920195; PFAM: RNA pseudouridylate synthase; pseudouridine synthase 1545602 10579807 Trebr_1303 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004439861.1 1544805 D 906968 CDS YP_004439862.1 332297940 10579808 1545652..1546668 1 NC_015500.1 COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: sth:STH3219 iron ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Iron ABC transporter substrate-binding protein; IMG reference gene:2504920196; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 1546668 10579808 Trebr_1304 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004439862.1 1545652 D 906968 CDS YP_004439863.1 332297941 10579809 1546665..1548323 1 NC_015500.1 COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Iron(III)-transport system permease protein SfuB; IMG reference gene:2504920197; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1548323 10579809 Trebr_1305 Treponema brennaborense DSM 12168 ABC transporter permease YP_004439863.1 1546665 D 906968 CDS YP_004439864.1 332297942 10579810 1548320..1549456 1 NC_015500.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: bbe:BBR47_06250 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; Transport-associated OB, type 2; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP-binding protein; IMG reference gene:2504920198; PFAM: ABC transporter; polyamine-transporting ATPase 1549456 10579810 Trebr_1306 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004439864.1 1548320 D 906968 CDS YP_004439865.1 332297943 10579811 complement(1549431..1550762) 1 NC_015500.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR001645; KEGG: tde:TDE1084 folylpolyglutamate synthetase, PFAM: Mur ligase, C-terminal; Mur ligase, central; PRIAM: Tetrahydrofolate synthase; SPTR: Folylpolyglutamate synthetase, ; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504920199; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1550762 10579811 Trebr_1307 Treponema brennaborense DSM 12168 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_004439865.1 1549431 R 906968 CDS YP_004439866.1 332297944 10579812 complement(1550949..1553699) 1 NC_015500.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); HAMAP: Protein translocase subunit secA; InterProIPR011115:IPR011130:IPR011116:IPR004027:IPR 000185; KEGG: tde:TDE1898 preprotein translocase subunit SecA; PFAM: SecA DEAD-like; SecA preprotein cross-linking region; SecA Wing/Scaffold; SEC-C motif; SPTR: Protein translocase subunit secA; TIGRFAM: SecA protein; IMG reference gene:2504920200; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit; protein translocase subunit secA 1553699 10579812 Trebr_1308 Treponema brennaborense DSM 12168 protein translocase subunit secA YP_004439866.1 1550949 R 906968 CDS YP_004439867.1 332297945 10579813 1553787..1554995 1 NC_015500.1 KEGG: tde:TDE0857 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504920201; lipoprotein 1554995 10579813 Trebr_1309 Treponema brennaborense DSM 12168 lipoprotein YP_004439867.1 1553787 D 906968 CDS YP_004439868.1 332297946 10579814 1554998..1555561 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504920202; hypothetical protein 1555561 10579814 Trebr_1310 Treponema brennaborense DSM 12168 hypothetical protein YP_004439868.1 1554998 D 906968 CDS YP_004439869.1 332297947 10579815 1555600..1556034 1 NC_015500.1 KEGG: sta:STHERM_c07530 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920203; hypothetical protein 1556034 10579815 Trebr_1311 Treponema brennaborense DSM 12168 hypothetical protein YP_004439869.1 1555600 D 906968 CDS YP_004439870.1 332297948 10579816 1556034..1556441 1 NC_015500.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: dap:Dacet_2915 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: CTP pyrophosphohydrolase; IMG reference gene:2504920204; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein; NUDIX hydrolase 1556441 10579816 Trebr_1312 Treponema brennaborense DSM 12168 NUDIX hydrolase YP_004439870.1 1556034 D 906968 CDS YP_004439871.1 332297949 10579817 1556438..1556881 1 NC_015500.1 KEGG: tpp:TPASS_0069 hypothetical protein; SPTR: Lipoprotein, ; IMG reference gene:2504920205; hypothetical protein 1556881 10579817 Trebr_1313 Treponema brennaborense DSM 12168 hypothetical protein YP_004439871.1 1556438 D 906968 CDS YP_004439872.1 332297950 10579818 complement(1556888..1557604) 1 NC_015500.1 COGs: COG1738 conserved hypothetical protein; InterPro IPR003744; KEGG: tde:TDE0849 hypothetical protein; PFAM: Protein of unknown function DUF165; SPTR: uncharacterized protein; TIGRFAM: Protein of unknown function DUF165; IMG reference gene:2504920206; PFAM: Uncharacterized ACR, YhhQ family COG1738; TIGRFAM: conserved hypothetical integral membrane protein; hypothetical protein 1557604 10579818 Trebr_1314 Treponema brennaborense DSM 12168 hypothetical protein YP_004439872.1 1556888 R 906968 CDS YP_004439873.1 332297951 10579819 1557772..1559775 1 NC_015500.1 COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR004846; KEGG: tde:TDE1556 hypothetical protein; PFAM: Type II/III secretion system; SPTR: Type II and III secretion system protein; IMG reference gene:2504920207; PFAM: Bacterial type II and III secretion system protein; type II and III secretion system protein 1559775 10579819 Trebr_1315 Treponema brennaborense DSM 12168 type II and III secretion system protein YP_004439873.1 1557772 D 906968 CDS YP_004439874.1 332297952 10579820 1559765..1561117 1 NC_015500.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR003593:IPR001482; KEGG: hor:Hore_05970 Tfp pilus assembly protein PilB; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Tfp pilus assembly protein PilB; IMG reference gene:2504920208; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; type II secretion system protein E 1561117 10579820 Trebr_1316 Treponema brennaborense DSM 12168 type II secretion system protein E YP_004439874.1 1559765 D 906968 CDS YP_004439875.1 332297953 10579821 1561083..1562036 1 NC_015500.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: ctu:Ctu_07380 type IV pilin biogenesis protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein F domain protein; IMG reference gene:2504920209; PFAM: Bacterial type II secretion system protein F domain; type II secretion system F domain-containing protein 1562036 10579821 Trebr_1317 Treponema brennaborense DSM 12168 type II secretion system F domain-containing protein YP_004439875.1 1561083 D 906968 CDS YP_004439876.1 332297954 10579822 1562036..1562473 1 NC_015500.1 COGs: COG2165 Type II secretory pathway pseudopilin PulG; InterPro IPR012902:IPR013545:IPR010054; KEGG: gau:GAU_2075 general secretion pathway protein G; PFAM: Type II secretion system protein G; Prepilin-type cleavage/methylation, N-terminal; SPTR: General secretion pathway protein G; TIGRFAM: General secretion pathway protein G; Prepilin-type cleavage/methylation, N-terminal; IMG reference gene:2504920210; PFAM: Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain; general secretion pathway protein G 1562473 10579822 Trebr_1318 Treponema brennaborense DSM 12168 general secretion pathway protein G YP_004439876.1 1562036 D 906968 CDS YP_004439877.1 332297955 10579823 1562445..1562648 1 NC_015500.1 IMG reference gene:2504920211; hypothetical protein 1562648 10579823 Trebr_1319 Treponema brennaborense DSM 12168 hypothetical protein YP_004439877.1 1562445 D 906968 CDS YP_004439878.1 332297956 10579824 1562635..1562967 1 NC_015500.1 IMG reference gene:2504920212; hypothetical protein 1562967 10579824 Trebr_1320 Treponema brennaborense DSM 12168 hypothetical protein YP_004439878.1 1562635 D 906968 CDS YP_004439879.1 332297957 10579825 1562964..1564193 1 NC_015500.1 IMG reference gene:2504920213; hypothetical protein 1564193 10579825 Trebr_1321 Treponema brennaborense DSM 12168 hypothetical protein YP_004439879.1 1562964 D 906968 CDS YP_004439880.1 332297958 10579826 1564217..1564837 1 NC_015500.1 KEGG: tde:TDE1552 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920214; hypothetical protein 1564837 10579826 Trebr_1322 Treponema brennaborense DSM 12168 hypothetical protein YP_004439880.1 1564217 D 906968 CDS YP_004439881.1 332297959 10579827 1564831..1565277 1 NC_015500.1 IMG reference gene:2504920215; hypothetical protein 1565277 10579827 Trebr_1323 Treponema brennaborense DSM 12168 hypothetical protein YP_004439881.1 1564831 D 906968 CDS YP_004439882.1 332297960 10579828 1565282..1567387 1 NC_015500.1 InterPro IPR005077; KEGG: gme:Gmet_1209 hypothetical protein; PFAM: Peptidase C11, clostripain; SPTR: Peptidase C11 clostripain; IMG reference gene:2504920216; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); Clostripain family; peptidase C11 clostripain 1567387 10579828 Trebr_1324 Treponema brennaborense DSM 12168 peptidase C11 clostripain YP_004439882.1 1565282 D 906968 CDS YP_004439883.1 332297961 10579829 1567403..1573684 1 NC_015500.1 COGs: COG3209 Rhs family protein; InterPro IPR006530; KEGG: hor:Hore_18610 YD repeat protein; PFAM: YD repeat; SPTR: YD repeat protein; TIGRFAM: RHS repeat-associated core domain; YD repeat; IMG reference gene:2504920217; PFAM: RHS Repeat; TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies); RHS repeat-associated core domain-containing protein 1573684 10579829 Trebr_1325 Treponema brennaborense DSM 12168 RHS repeat-associated core domain-containing protein YP_004439883.1 1567403 D 906968 CDS YP_004439884.1 332297962 10579830 1573695..1575104 1 NC_015500.1 KEGG: tde:TDE1705 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920218; hypothetical protein 1575104 10579830 Trebr_1326 Treponema brennaborense DSM 12168 hypothetical protein YP_004439884.1 1573695 D 906968 CDS YP_004439885.1 332297963 10579831 1575104..1575631 1 NC_015500.1 KEGG: hor:Hore_18610 YD repeat protein; SPTR: YD repeat protein; IMG reference gene:2504920219; hypothetical protein 1575631 10579831 Trebr_1327 Treponema brennaborense DSM 12168 hypothetical protein YP_004439885.1 1575104 D 906968 CDS YP_004439886.1 332297964 10579832 1575676..1576167 1 NC_015500.1 IMG reference gene:2504920220; hypothetical protein 1576167 10579832 Trebr_1328 Treponema brennaborense DSM 12168 hypothetical protein YP_004439886.1 1575676 D 906968 CDS YP_004439887.1 332297965 10579834 1577845..1579086 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504920222; PFAM: Transposase, Mutator family; transposase mutator type 1579086 10579834 Trebr_1330 Treponema brennaborense DSM 12168 transposase mutator type YP_004439887.1 1577845 D 906968 CDS YP_004439888.1 332297966 10579836 1579511..1580047 1 NC_015500.1 IMG reference gene:2504920224; hypothetical protein 1580047 10579836 Trebr_1332 Treponema brennaborense DSM 12168 hypothetical protein YP_004439888.1 1579511 D 906968 CDS YP_004439889.1 332297967 10579837 1580063..1580722 1 NC_015500.1 IMG reference gene:2504920225; hypothetical protein 1580722 10579837 Trebr_1333 Treponema brennaborense DSM 12168 hypothetical protein YP_004439889.1 1580063 D 906968 CDS YP_004439890.1 332297968 10579839 1581573..1582814 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504920227; PFAM: Transposase, Mutator family; transposase mutator type 1582814 10579839 Trebr_1335 Treponema brennaborense DSM 12168 transposase mutator type YP_004439890.1 1581573 D 906968 CDS YP_004439891.1 332297969 10579840 1583563..1584189 1 NC_015500.1 IMG reference gene:2504920228; hypothetical protein 1584189 10579840 Trebr_1336 Treponema brennaborense DSM 12168 hypothetical protein YP_004439891.1 1583563 D 906968 CDS YP_004439892.1 332297970 10579841 1584370..1584813 1 NC_015500.1 IMG reference gene:2504920229; hypothetical protein 1584813 10579841 Trebr_1337 Treponema brennaborense DSM 12168 hypothetical protein YP_004439892.1 1584370 D 906968 CDS YP_004439893.1 332297971 10579842 1584810..1585331 1 NC_015500.1 IMG reference gene:2504920230; hypothetical protein 1585331 10579842 Trebr_1338 Treponema brennaborense DSM 12168 hypothetical protein YP_004439893.1 1584810 D 906968 CDS YP_004439894.1 332297972 10579843 1585488..1586414 1 NC_015500.1 IMG reference gene:2504920231; hypothetical protein 1586414 10579843 Trebr_1339 Treponema brennaborense DSM 12168 hypothetical protein YP_004439894.1 1585488 D 906968 CDS YP_004439895.1 332297973 10579844 1586450..1587445 1 NC_015500.1 COGs: COG2378 transcriptional regulator protein; KEGG: dau:Daud_1294 regulatory protein, DeoR; SPTR: HTH domain family; IMG reference gene:2504920232; regulatory protein, DeoR 1587445 10579844 Trebr_1340 Treponema brennaborense DSM 12168 regulatory protein, DeoR YP_004439895.1 1586450 D 906968 CDS YP_004439896.1 332297974 10579845 complement(1587618..1588925) 1 NC_015500.1 COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: tde:TDE1442 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; IMG reference gene:2504920233; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; histidyl-tRNA synthetase 1588925 10579845 Trebr_1341 Treponema brennaborense DSM 12168 histidyl-tRNA synthetase YP_004439896.1 1587618 R 906968 CDS YP_004439897.1 332297975 10579846 1588961..1589782 1 NC_015500.1 COGs: COG1521 transcriptional regulator protein; HAMAP: Type III pantothenate kinase; InterPro IPR004619; KEGG: sli:Slin_6393 transcriptional acitvator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor; PRIAM: Pantothenate kinase; SPTR: Type III pantothenate kinase 2; TIGRFAM: Bordetella pertussis Bvg accessory factor; IMG reference gene:2504920234; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III; Baf family transcriptional acitvator 1589782 10579846 Trebr_1342 Treponema brennaborense DSM 12168 Baf family transcriptional acitvator YP_004439897.1 1588961 D 906968 CDS YP_004439898.1 332297976 10579848 1590163..1591452 1 NC_015500.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: tde:TDE1360 xanthine/uracil permease family protein; PFAM: Xanthine/uracil/vitamin C permease; SPTR: integral membrane protein; IMG reference gene:2504920236; PFAM: Permease family; xanthine/uracil/vitamin C permease 1591452 10579848 Trebr_1343 Treponema brennaborense DSM 12168 xanthine/uracil/vitamin C permease YP_004439898.1 1590163 D 906968 CDS YP_004439899.1 332297977 10579849 1591617..1592117 1 NC_015500.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: tde:TDE2193 deoxycytidylate deaminase, PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: dCMP deaminase; IMG reference gene:2504920237; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; CMP/dCMP deaminase zinc-binding protein 1592117 10579849 Trebr_1344 Treponema brennaborense DSM 12168 CMP/dCMP deaminase zinc-binding protein YP_004439899.1 1591617 D 906968 CDS YP_004439900.1 332297978 10579850 complement(1592166..1593578) 1 NC_015500.1 COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: tde:TDE2192 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase, ; TIGRFAM: Threonine synthase; IMG reference gene:2504920238; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; threonine synthase 1593578 10579850 Trebr_1345 Treponema brennaborense DSM 12168 threonine synthase YP_004439900.1 1592166 R 906968 CDS YP_004439901.1 332297979 10579851 complement(1593705..1594775) 1 NC_015500.1 KEGG: ssm:Spirs_3904 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920239; hypothetical protein 1594775 10579851 Trebr_1346 Treponema brennaborense DSM 12168 hypothetical protein YP_004439901.1 1593705 R 906968 CDS YP_004439902.1 332297980 10579852 1594849..1596021 1 NC_015500.1 COGs: COG0787 Alanine racemase; HAMAP: Alanine racemase; InterPro IPR000821:IPR001608:IPR011079; KEGG: tde:TDE1095 alanine racemase; PFAM: Alanine racemase, N-terminal; Alanine racemase, C-terminal; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: Alanine racemase; IMG reference gene:2504920240; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase; alanine racemase 1596021 10579852 Trebr_1347 Treponema brennaborense DSM 12168 alanine racemase YP_004439902.1 1594849 D 906968 CDS YP_004439903.1 332297981 10579853 1596063..1596953 1 NC_015500.1 COGs: COG1814 Uncharacterized membrane protein; InterPro IPR003251:IPR008217; KEGG: brm:Bmur_1173 protein of unknown function DUF125 transmembrane; PFAM: Protein of unknown function DUF125, transmembrane; Rubrerythrin; SPTR: uncharacterized protein; IMG reference gene:2504920241; PFAM: Rubrerythrin; VIT family; hypothetical protein 1596953 10579853 Trebr_1348 Treponema brennaborense DSM 12168 hypothetical protein YP_004439903.1 1596063 D 906968 CDS YP_004439904.1 332297982 10579855 1597314..1597544 1 NC_015500.1 COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: tde:TDE2661 hypothetical protein; PFAM: Regulatory protein, FmdB, SPTR: uncharacterized protein; TIGRFAM: Regulatory protein, FmdB, IMG reference gene:2504920243; PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family; FmdB family regulatory protein 1597544 10579855 Trebr_1349 Treponema brennaborense DSM 12168 FmdB family regulatory protein YP_004439904.1 1597314 D 906968 CDS YP_004439905.1 332297983 10579856 1597548..1597943 1 NC_015500.1 KEGG: tde:TDE2660 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920244; hypothetical protein 1597943 10579856 Trebr_1350 Treponema brennaborense DSM 12168 hypothetical protein YP_004439905.1 1597548 D 906968 CDS YP_004439906.1 332297984 10579857 complement(1597935..1598747) 1 NC_015500.1 KEGG: tde:TDE1088 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920245; hypothetical protein 1598747 10579857 Trebr_1351 Treponema brennaborense DSM 12168 hypothetical protein YP_004439906.1 1597935 R 906968 CDS YP_004439907.1 332297985 10579858 complement(1598744..1599718) 1 NC_015500.1 KEGG: tpp:TPASS_0455 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920246; hypothetical protein 1599718 10579858 Trebr_1352 Treponema brennaborense DSM 12168 hypothetical protein YP_004439907.1 1598744 R 906968 CDS YP_004439908.1 332297986 10579859 1599781..1603338 1 NC_015500.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR014001:IPR001650:IPR003711:IPR011545:IPR 005118:IPR004576; KEGG: tde:TDE1287 transcription-repair coupling factor; PFAM: Transcription factor CarD; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Transcription-repair-coupling factor; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Transcription-repair coupling factor; TIGRFAM: Transcription-repair coupling factor; IMG reference gene:2504920247; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd); transcription-repair coupling factor 1603338 10579859 Trebr_1353 Treponema brennaborense DSM 12168 transcription-repair coupling factor YP_004439908.1 1599781 D 906968 CDS YP_004439909.1 332297987 10579860 1603368..1604009 1 NC_015500.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: aca:ACP_0419 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase family protein IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504920248; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Epoxide hydrolase N-terminal domain-like phosphatase; HAD-superfamily hydrolase 1604009 10579860 Trebr_1354 Treponema brennaborense DSM 12168 HAD-superfamily hydrolase YP_004439909.1 1603368 D 906968 CDS YP_004439910.1 332297988 10579861 complement(1604457..1605770) 1 NC_015500.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR011923; KEGG: tde:TDE1353 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: Rod shape-determining protein RodA; IMG reference gene:2504920249; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; rod shape-determining protein RodA 1605770 10579861 Trebr_1355 Treponema brennaborense DSM 12168 rod shape-determining protein RodA YP_004439910.1 1604457 R 906968 CDS YP_004439911.1 332297989 10579862 complement(1605791..1607671) 1 NC_015500.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: tde:TDE1352 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504920250; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; penicillin-binding protein 2 1607671 10579862 Trebr_1356 Treponema brennaborense DSM 12168 penicillin-binding protein 2 YP_004439911.1 1605791 R 906968 CDS YP_004439912.1 332297990 10579863 complement(1607671..1608171) 1 NC_015500.1 InterPro IPR007227; KEGG: tde:TDE1351 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; TIGRFAM: Cell shape-determining protein MreD; IMG reference gene:2504920251; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD; rod shape-determining protein MreD 1608171 10579863 Trebr_1357 Treponema brennaborense DSM 12168 rod shape-determining protein MreD YP_004439912.1 1607671 R 906968 CDS YP_004439913.1 332297991 10579864 complement(1608168..1609019) 1 NC_015500.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR007221:IPR005223; KEGG: tde:TDE1350 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; TIGRFAM: Rod shape-determining protein MreC, subtype; IMG reference gene:2504920252; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; rod shape-determining protein MreC 1609019 10579864 Trebr_1358 Treponema brennaborense DSM 12168 rod shape-determining protein MreC YP_004439913.1 1608168 R 906968 CDS YP_004439914.1 332297992 10579865 complement(1609033..1610070) 1 NC_015500.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: tde:TDE1349 rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504920253; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; MreB/Mrl family cell shape determining protein 1610070 10579865 Trebr_1359 Treponema brennaborense DSM 12168 MreB/Mrl family cell shape determining protein YP_004439914.1 1609033 R 906968 CDS YP_004439915.1 332297993 10579866 complement(1610086..1611045) 1 NC_015500.1 InterPro IPR019734:IPR001440:IPR013105; KEGG: tde:TDE1348 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920254; PFAM: Tetratricopeptide repeat; hypothetical protein 1611045 10579866 Trebr_1360 Treponema brennaborense DSM 12168 hypothetical protein YP_004439915.1 1610086 R 906968 CDS YP_004439916.1 332297994 10579868 complement(1611500..1612354) 1 NC_015500.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: ssm:Spirs_2077 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: uncharacterized protein; IMG reference gene:2504920256; PFAM: zinc ribbon domain; hypothetical protein 1612354 10579868 Trebr_1361 Treponema brennaborense DSM 12168 hypothetical protein YP_004439916.1 1611500 R 906968 CDS YP_004439917.1 332297995 10579869 complement(1612425..1614224) 1 NC_015500.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR007127:IPR009042:IPR007627:IPR007624:IPR 007630:IPR014284:IPR012760; KEGG: tde:TDE1346 RNA polymerase sigma factor RpoD; PFAM: RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma factor 70, region 1.1; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal; RNA polymerase sigma-70; IMG reference gene:2504920257; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain; RpoD subfamily RNA polymerase sigma-70 subunit 1614224 10579869 Trebr_1362 Treponema brennaborense DSM 12168 RpoD subfamily RNA polymerase sigma-70 subunit YP_004439917.1 1612425 R 906968 CDS YP_004439918.1 332297996 10579870 complement(1614237..1616021) 1 NC_015500.1 COGs: COG0358 DNA primase; InterProIPR002694:IPR006154:IPR013264:IPR006171:IPR 019475:IPR006295; KEGG: tde:TDE1345 DNA primase; SPTR: DNA primase; TIGRFAM: DNA primase, DnaG; IMG reference gene:2504920258; PFAM: Toprim domain; CHC2 zinc finger; DNA primase catalytic core, N-terminal domain; TIGRFAM: DNA primase, catalytic core; DNA primase 1616021 10579870 Trebr_1363 Treponema brennaborense DSM 12168 DNA primase YP_004439918.1 1614237 R 906968 CDS YP_004439919.1 332297997 10579871 complement(1616021..1617058) 1 NC_015500.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: tde:TDE1543 hypothetical protein; PFAM: Uncharacterised protein family YceG-like; SPTR: Aminodeoxychorismate lyase; TIGRFAM: Uncharacterised protein family YceG-like; IMG reference gene:2504920259; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family; aminodeoxychorismate lyase 1617058 10579871 Trebr_1364 Treponema brennaborense DSM 12168 aminodeoxychorismate lyase YP_004439919.1 1616021 R 906968 CDS YP_004439920.1 332297998 10579872 complement(1617119..1617316) 1 NC_015500.1 IMG reference gene:2504920260; hypothetical protein 1617316 10579872 Trebr_1365 Treponema brennaborense DSM 12168 hypothetical protein YP_004439920.1 1617119 R 906968 CDS YP_004439921.1 332297999 10579873 complement(1617313..1618254) 1 NC_015500.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: tde:TDE1541 metallo-beta-lactamase family protein; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504920261; PFAM: Metallo-beta-lactamase superfamily; metallo-beta-lactamase family protein 1618254 10579873 Trebr_1366 Treponema brennaborense DSM 12168 metallo-beta-lactamase family protein YP_004439921.1 1617313 R 906968 CDS YP_004439922.1 332298000 10579874 complement(1618268..1618714) 1 NC_015500.1 InterPro IPR005358; KEGG: tde:TDE1540 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: uncharacterized protein; IMG reference gene:2504920262; PFAM: Uncharacterised protein family (UPF0153); hypothetical protein 1618714 10579874 Trebr_1367 Treponema brennaborense DSM 12168 hypothetical protein YP_004439922.1 1618268 R 906968 CDS YP_004439923.1 332298001 10579877 complement(1619022..1620608) 1 NC_015500.1 COGs: COG0297 Glycogen synthase; InterPro IPR013534:IPR001296; KEGG: glycogen synthase (ADP-glucose); PFAM: Starch synthase catalytic region; Glycosyl transferase, group 1; PRIAM: Starch synthase; SPTR: Starch synthase catalytic domain protein; IMG reference gene:2504920265; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type; starch synthase 1620608 10579877 Trebr_1368 Treponema brennaborense DSM 12168 starch synthase YP_004439923.1 1619022 R 906968 CDS YP_004439924.1 332298002 10579878 complement(1620613..1621047) 1 NC_015500.1 COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: tde:TDE1502 chorismate mutase; PFAM: Chorismate mutase, AroH class; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroH class; IMG reference gene:2504920266; PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1; chorismate mutase 1621047 10579878 Trebr_1369 Treponema brennaborense DSM 12168 chorismate mutase YP_004439924.1 1620613 R 906968 CDS YP_004439925.1 332298003 10579879 complement(1621029..1621394) 1 NC_015500.1 manually curated; IMG reference gene:2504920267; hypothetical protein 1621394 10579879 Trebr_1370 Treponema brennaborense DSM 12168 hypothetical protein YP_004439925.1 1621029 R 906968 CDS YP_004439926.1 332298004 10579880 1621469..1622305 1 NC_015500.1 KEGG: tde:TDE2492 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920268; hypothetical protein 1622305 10579880 Trebr_1371 Treponema brennaborense DSM 12168 hypothetical protein YP_004439926.1 1621469 D 906968 CDS YP_004439927.1 332298005 10579881 complement(1622238..1623020) 1 NC_015500.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: tpp:TPASS_0518 hypothetical protein; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: uncharacterized protein; TIGRFAM: Thiamin pyrophosphokinase; IMG reference gene:2504920269; PFAM: Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase; thiamine pyrophosphokinase 1623020 10579881 Trebr_1372 Treponema brennaborense DSM 12168 thiamine pyrophosphokinase YP_004439927.1 1622238 R 906968 CDS YP_004439928.1 332298006 10579882 1623064..1624473 1 NC_015500.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674; KEGG: tde:TDE1033 polyA polymerase family protein; PFAM: Polynucleotide adenylyltransferase region; Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: tRNA adenylyltransferase; IMG reference gene:2504920270; PFAM: HD domain; Poly A polymerase head domain; polynucleotide adenylyltransferase/metal dependent phosphohydrolase 1624473 10579882 Trebr_1373 Treponema brennaborense DSM 12168 polynucleotide adenylyltransferase/metal dependent phosphohydrolase YP_004439928.1 1623064 D 906968 CDS YP_004439929.1 332298007 10579883 complement(1624507..1625577) 1 NC_015500.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002305:IPR002306; KEGG: ssm:Spirs_4220 tryptophanyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib; IMG reference gene:2504920271; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 1625577 10579883 Trebr_1374 Treponema brennaborense DSM 12168 tryptophanyl-tRNA synthetase YP_004439929.1 1624507 R 906968 CDS YP_004439930.1 332298008 10579884 complement(1625614..1626687) 1 NC_015500.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: ssm:Spirs_2888 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: FemAB family protein; IMG reference gene:2504920272; PFAM: FemAB family; Methicillin resistance protein 1626687 10579884 Trebr_1375 Treponema brennaborense DSM 12168 Methicillin resistance protein YP_004439930.1 1625614 R 906968 CDS YP_004439931.1 332298009 10579885 complement(1626694..1629039) 1 NC_015500.1 COGs: COG0143 Methionyl-tRNA synthetase; HAMAP: Methionyl-tRNA synthetase; InterPro IPR015413:IPR002547:IPR002304; KEGG: tde:TDE1063 methionyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); tRNA-binding region; PRIAM: Methionine--tRNA ligase; SPTR: Methionyl-tRNA synthetase; TIGRFAM: Methionyl-tRNA synthetase, class Ia; IMG reference gene:2504920273; PFAM: tRNA synthetases class I (M); Anticodon-binding domain; tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase; Methionyl-tRNA synthetase 1629039 10579885 Trebr_1376 Treponema brennaborense DSM 12168 Methionyl-tRNA synthetase YP_004439931.1 1626694 R 906968 CDS YP_004439932.1 332298010 10579886 complement(1629207..1631081) 1 NC_015500.1 InterPro IPR004300:IPR015179; KEGG: tde:TDE1395 glycosy hydrolase family protein; PFAM: Glycoside hydrolase, family 57, core; Alpha-amylase/4-alpha-glucanotransferase, prokaryotic; SPTR: Glycosyl hydrolase, family 57; IMG reference gene:2504920274; PFAM: Glycosyl hydrolase family 57; Domain of unknown function (DUF1926); glycoside hydrolase family protein 1631081 10579886 Trebr_1377 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004439932.1 1629207 R 906968 CDS YP_004439933.1 332298011 10579887 complement(1631121..1631705) 1 NC_015500.1 InterPro IPR001450; KEGG: cni:Calni_0585 electron transport complex, rnfabcdge type, B subunit; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: uncharacterized protein; IMG reference gene:2504920275; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 1631705 10579887 Trebr_1378 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004439933.1 1631121 R 906968 CDS YP_004439934.1 332298012 10579888 complement(1631702..1632250) 1 NC_015500.1 KEGG: tde:TDE1394 hypothetical protein; SPTR: Membrane protein, ; IMG reference gene:2504920276; hypothetical protein 1632250 10579888 Trebr_1379 Treponema brennaborense DSM 12168 hypothetical protein YP_004439934.1 1631702 R 906968 CDS YP_004439935.1 332298013 10579889 complement(1632240..1632878) 1 NC_015500.1 KEGG: tde:TDE1393 hypothetical protein; SPTR: membrane protein; IMG reference gene:2504920277; hypothetical protein 1632878 10579889 Trebr_1380 Treponema brennaborense DSM 12168 hypothetical protein YP_004439935.1 1632240 R 906968 CDS YP_004439936.1 332298014 10579890 complement(1632884..1633375) 1 NC_015500.1 IMG reference gene:2504920278; hypothetical protein 1633375 10579890 Trebr_1381 Treponema brennaborense DSM 12168 hypothetical protein YP_004439936.1 1632884 R 906968 CDS YP_004439937.1 332298015 10579891 complement(1633410..1634468) 1 NC_015500.1 COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; KEGG: tde:TDE1391 NQR2/RnfD/RnfE family protein; SPTR: NQR2/RnfD/RnfE family protein; IMG reference gene:2504920279; PFAM: NQR2, RnfD, RnfE family; NQR2/RnfD/RnfE family protein 1634468 10579891 Trebr_1382 Treponema brennaborense DSM 12168 NQR2/RnfD/RnfE family protein YP_004439937.1 1633410 R 906968 CDS YP_004439938.1 332298016 10579892 complement(1634455..1635741) 1 NC_015500.1 COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR011538:IPR019554; KEGG: ssm:Spirs_1909 electron transport complex, RnfABCDGE type, C subunit; PFAM: Soluble ligand binding domain; NADH:ubiquinone oxidoreductase, 51kDa subunit; SPTR: Nitrogen fixation protein; IMG reference gene:2504920280; PFAM: Na(+)-translocating NADH-quinone reductase subunit A (NQRA); SLBB domain; Soluble ligand binding domain-containing protein 1635741 10579892 Trebr_1383 Treponema brennaborense DSM 12168 Soluble ligand binding domain-containing protein YP_004439938.1 1634455 R 906968 CDS YP_004439939.1 332298017 10579893 complement(1635738..1637198) 1 NC_015500.1 KEGG: tde:TDE1389 hypothetical protein; SPTR: membrane protein; IMG reference gene:2504920281; hypothetical protein 1637198 10579893 Trebr_1384 Treponema brennaborense DSM 12168 hypothetical protein YP_004439939.1 1635738 R 906968 CDS YP_004439940.1 332298018 10579894 complement(1637210..1637689) 1 NC_015500.1 COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: tde:TDE1388 hypothetical protein; PFAM: Acid phosphatase/vanadium-dependent haloperoxidase related; SPTR: Integral membrane protein; IMG reference gene:2504920282; PFAM: Divergent PAP2 family; acid phosphatase/vanadium-dependent haloperoxidase related protein 1637689 10579894 Trebr_1385 Treponema brennaborense DSM 12168 acid phosphatase/vanadium-dependent haloperoxidase related protein YP_004439940.1 1637210 R 906968 CDS YP_004439941.1 332298019 10579895 1637765..1638775 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942:IPR006145; KEGG: sta:STHERM_c04380 ribosomal large subunit pseudouridine synthase C; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; IMG reference gene:2504920283; PFAM: RNA pseudouridylate synthase; S4 domain; pseudouridine synthase 1638775 10579895 Trebr_1386 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004439941.1 1637765 D 906968 CDS YP_004439942.1 332298020 10579896 1638772..1639656 1 NC_015500.1 KEGG: tde:TDE1967 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920284; hypothetical protein 1639656 10579896 Trebr_1387 Treponema brennaborense DSM 12168 hypothetical protein YP_004439942.1 1638772 D 906968 CDS YP_004439943.1 332298021 10579897 complement(1639663..1640943) 1 NC_015500.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR010206; KEGG: tde:TDE1726 polyA polymerase family protein; PFAM: Polynucleotide adenylyltransferase region; PRIAM: Polynucleotide adenylyltransferase; SPTR: PolyA polymerase family protein; TIGRFAM: Poly(A) polymerase, PcnB; IMG reference gene:2504920285; PFAM: Poly A polymerase head domain; TIGRFAM: poly(A) polymerase; poly(A) polymerase 1640943 10579897 Trebr_1388 Treponema brennaborense DSM 12168 poly(A) polymerase YP_004439943.1 1639663 R 906968 CDS YP_004439944.1 332298022 10579898 1641092..1642378 1 NC_015500.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076; KEGG: sta:STHERM_c17830 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: uncharacterized protein; IMG reference gene:2504920286; FAD dependent oxidoreductase 1642378 10579898 Trebr_1389 Treponema brennaborense DSM 12168 FAD dependent oxidoreductase YP_004439944.1 1641092 D 906968 CDS YP_004439945.1 332298023 10579899 1642407..1642961 1 NC_015500.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR016065:IPR004398; KEGG: tde:TDE1881 methyltransferase, PFAM: Protein of unknown function methylase SPTR: Methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; IMG reference gene:2504920287; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; methyltransferase 1642961 10579899 Trebr_1390 Treponema brennaborense DSM 12168 methyltransferase YP_004439945.1 1642407 D 906968 CDS YP_004439946.1 332298024 10579900 1643043..1643387 1 NC_015500.1 KEGG: tde:TDE2072 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920288; hypothetical protein 1643387 10579900 Trebr_1391 Treponema brennaborense DSM 12168 hypothetical protein YP_004439946.1 1643043 D 906968 CDS YP_004439947.1 332298025 10579901 1643393..1644568 1 NC_015500.1 InterPro IPR019734:IPR001440:IPR013105; KEGG: ssm:Spirs_3144 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920289; PFAM: Tetratricopeptide repeat; hypothetical protein 1644568 10579901 Trebr_1392 Treponema brennaborense DSM 12168 hypothetical protein YP_004439947.1 1643393 D 906968 CDS YP_004439948.1 332298026 10579902 1644575..1645603 1 NC_015500.1 COGs: COG0820 Fe-S-cluster redox enzyme; HAMAP: Ribosomal RNA large subunit methyltransferase RlmN; InterPro IPR004383:IPR007197; KEGG: tde:TDE2074 radical SAM protein; PFAM: Radical SAM; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: Ribosomal RNA large subunit methyltransferase RlmN; IMG reference gene:2504920290; PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase; ribosomal RNA large subunit methyltransferase N 1645603 10579902 Trebr_1393 Treponema brennaborense DSM 12168 ribosomal RNA large subunit methyltransferase N YP_004439948.1 1644575 D 906968 CDS YP_004439949.1 332298027 10579903 1645653..1645862 1 NC_015500.1 InterPro IPR006121; PFAM: Heavy metal transport/detoxification protein; IMG reference gene:2504920291; PFAM: Heavy-metal-associated domain; heavy metal transport/detoxification protein 1645862 10579903 Trebr_1394 Treponema brennaborense DSM 12168 heavy metal transport/detoxification protein YP_004439949.1 1645653 D 906968 CDS YP_004439950.1 332298028 10579904 1645862..1646809 1 NC_015500.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: ppd:Ppro_2951 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: uncharacterized protein; IMG reference gene:2504920292; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Phosphoglycerate dehydrogenase 1646809 10579904 Trebr_1395 Treponema brennaborense DSM 12168 Phosphoglycerate dehydrogenase YP_004439950.1 1645862 D 906968 CDS YP_004439951.1 332298029 10579905 complement(1646842..1647483) 1 NC_015500.1 COGs: COG1896 hydrolase of HD superfamily; KEGG: npu:Npun_R6315 HD superfamily hydrolase; SPTR: Hydrolase of HD superfamily; IMG reference gene:2504920293; HD superfamily hydrolase 1647483 10579905 Trebr_1396 Treponema brennaborense DSM 12168 HD superfamily hydrolase YP_004439951.1 1646842 R 906968 CDS YP_004439952.1 332298030 10579906 complement(1647628..1648161) 1 NC_015500.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573; KEGG: ccb:Clocel_2601 aconitate hydratase domain-containing protein; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Aconitate hydratase domain protein; IMG reference gene:2504920294; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; aconitate hydratase domain-containing protein 1648161 10579906 Trebr_1397 Treponema brennaborense DSM 12168 aconitate hydratase domain-containing protein YP_004439952.1 1647628 R 906968 CDS YP_004439953.1 332298031 10579907 complement(1648158..1649468) 1 NC_015500.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR001030:IPR006251; KEGG: ccb:Clocel_2602 homoaconitate hydratase family protein; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; IMG reference gene:2504920295; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; homoaconitate hydratase family protein 1649468 10579907 Trebr_1398 Treponema brennaborense DSM 12168 homoaconitate hydratase family protein YP_004439953.1 1648158 R 906968 CDS YP_004439954.1 332298032 10579908 1649709..1650812 1 NC_015500.1 COGs: COG0225 Peptide methionine sulfoxide reductase; HAMAP: Peptide methionine sulphoxide reductase MsrA; Peptide methionine sulfoxide reductase msrB; InterPro IPR002569:IPR002579; KEGG: bfs:BF3378 bifunctional methionine sulfoxide reductase A/B protein; PFAM: Methionine sulphoxide reductase B; Peptide methionine sulphoxide reductase MsrA; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: uncharacterized protein; TIGRFAM: Methionine sulphoxide reductase B; Peptide methionine sulphoxide reductase MsrA; IMG reference gene:2504920296; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase; Peptide methionine sulfoxide reductase msrA 1650812 10579908 Trebr_1399 Treponema brennaborense DSM 12168 Peptide methionine sulfoxide reductase msrA YP_004439954.1 1649709 D 906968 CDS YP_004439955.1 332298033 10579909 complement(1650855..1651850) 1 NC_015500.1 InterPro IPR001387; KEGG: dsy:DSY1729 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: helix-turn-helix protein; IMG reference gene:2504920297; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 1651850 10579909 Trebr_1400 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004439955.1 1650855 R 906968 CDS YP_004439956.1 332298034 10579910 complement(1652093..1654756) 1 NC_015500.1 COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121:IPR010121; KEGG: ssm:Spirs_1716 pyruvate, phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; IMG reference gene:2504920298; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; pyruvate, phosphate dikinase 1654756 10579910 Trebr_1401 Treponema brennaborense DSM 12168 pyruvate, phosphate dikinase YP_004439956.1 1652093 R 906968 CDS YP_004439957.1 332298035 10579911 1654837..1656177 1 NC_015500.1 COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: emi:Emin_0760 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: enzyme of poly-gamma-glutamate biosynthesis; IMG reference gene:2504920299; PFAM: Bacterial capsule synthesis protein PGA_cap; capsule synthesis protein CapA 1656177 10579911 Trebr_1402 Treponema brennaborense DSM 12168 capsule synthesis protein CapA YP_004439957.1 1654837 D 906968 CDS YP_004439958.1 332298036 10579912 1656174..1658735 1 NC_015500.1 COGs: COG1643 HrpA-like helicase; InterPro IPR014001:IPR001650:IPR007502:IPR011709; KEGG: tde:TDE1654 ATP-dependent helicase HrpA, PFAM: DNA/RNA helicase, C-terminal; Helicase-associated region; Domain of unknown function DUF1605; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent helicase HrpA, ; IMG reference gene:2504920300; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); DEAD/DEAH box helicase; Domain of unknown function (DUF1605); TIGRFAM: ATP-dependent helicase HrpA; helicase domain-containing protein 1658735 10579912 Trebr_1403 Treponema brennaborense DSM 12168 helicase domain-containing protein YP_004439958.1 1656174 D 906968 CDS YP_004439959.1 332298037 10579913 complement(1658920..1659648) 1 NC_015500.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: tde:TDE0294 TrkA domain-containing protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: TrkA domain protein; IMG reference gene:2504920301; PFAM: TrkA-N domain; TrkA-C domain; TrkA-N domain-containing protein 1659648 10579913 Trebr_1404 Treponema brennaborense DSM 12168 TrkA-N domain-containing protein YP_004439959.1 1658920 R 906968 CDS YP_004439960.1 332298038 10579914 complement(1659733..1661070) 1 NC_015500.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: bdu:BDU_727 K transport protein; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: K transport protein; IMG reference gene:2504920302; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family; H(+)-transporting two-sector ATPase 1661070 10579914 Trebr_1405 Treponema brennaborense DSM 12168 H(+)-transporting two-sector ATPase YP_004439960.1 1659733 R 906968 CDS YP_004439961.1 332298039 10579915 complement(1661109..1662362) 1 NC_015500.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR010723:IPR004559; KEGG: det:DET0858 oxygen-independent coproporphyrinogen III oxidase, PFAM: Radical SAM; HemN, C-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: Oxygen-independent coproporphyrinogen III oxidase, ; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; IMG reference gene:2504920303; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; oxygen-independent coproporphyrinogen III oxidase 1662362 10579915 Trebr_1406 Treponema brennaborense DSM 12168 oxygen-independent coproporphyrinogen III oxidase YP_004439961.1 1661109 R 906968 CDS YP_004439962.1 332298040 10579916 complement(1662367..1663062) 1 NC_015500.1 InterPro IPR019759:IPR000223; KEGG: tde:TDE1465 signal peptidase I, PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I, ; TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504920304; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; signal peptidase I 1663062 10579916 Trebr_1407 Treponema brennaborense DSM 12168 signal peptidase I YP_004439962.1 1662367 R 906968 CDS YP_004439963.1 332298041 10579917 complement(1663119..1663880) 1 NC_015500.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR011286; KEGG: eel:EUBELI_00528 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 2-deoxy-D-gluconate 3-dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; IMG reference gene:2504920305; PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; 2-deoxy-D-gluconate 3-dehydrogenase 1663880 10579917 Trebr_1408 Treponema brennaborense DSM 12168 2-deoxy-D-gluconate 3-dehydrogenase YP_004439963.1 1663119 R 906968 CDS YP_004439964.1 332298042 10579918 1664066..1668031 1 NC_015500.1 InterPro IPR003961; KEGG: ckn:Calkro_0121 glycoside hydrolase family 16; SPTR: Glycoside hydrolase family 16; IMG reference gene:2504920306; PFAM: Fibronectin type III domain; hypothetical protein 1668031 10579918 Trebr_1409 Treponema brennaborense DSM 12168 hypothetical protein YP_004439964.1 1664066 D 906968 CDS YP_004439965.1 332298043 10579919 1668036..1670204 1 NC_015500.1 InterPro IPR003961; KEGG: dal:Dalk_3355 fibronectin type III domain protein; PFAM: Fibronectin, type III; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504920307; fibronectin type III domain-containing protein 1670204 10579919 Trebr_1410 Treponema brennaborense DSM 12168 fibronectin type III domain-containing protein YP_004439965.1 1668036 D 906968 CDS YP_004439966.1 332298044 10579920 1670227..1670589 1 NC_015500.1 IMG reference gene:2504920308; hypothetical protein 1670589 10579920 Trebr_1411 Treponema brennaborense DSM 12168 hypothetical protein YP_004439966.1 1670227 D 906968 CDS YP_004439967.1 332298045 10579921 1670602..1671456 1 NC_015500.1 IMG reference gene:2504920309; hypothetical protein 1671456 10579921 Trebr_1412 Treponema brennaborense DSM 12168 hypothetical protein YP_004439967.1 1670602 D 906968 CDS YP_004439968.1 332298046 10579922 complement(1671535..1672305) 1 NC_015500.1 COGs: COG0571 dsRNA-specific ribonuclease; HAMAP: Ribonuclease III, bacterial; InterPro IPR000999:IPR001159:IPR011907; KEGG: tde:TDE1027 ribonuclease III; PFAM: Ribonuclease III; Double-stranded RNA binding; PRIAM: Ribonuclease III; SMART: Ribonuclease III; Double-stranded RNA binding; SPTR: Ribonuclease 3; TIGRFAM: Ribonuclease III, bacterial; IMG reference gene:2504920310; PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial; ribonuclease 3 1672305 10579922 Trebr_1413 Treponema brennaborense DSM 12168 ribonuclease 3 YP_004439968.1 1671535 R 906968 CDS YP_004439969.1 332298047 10579923 complement(1672356..1672592) 1 NC_015500.1 COGs: COG0236 Acyl carrier protein; HAMAP: Acyl carrier protein (ACP); InterPro IPR003231:IPR006163; KEGG: tde:TDE1026 acyl carrier protein; PFAM: Phosphopantetheine-binding; SPTR: Acyl carrier protein; TIGRFAM: Acyl carrier protein (ACP); IMG reference gene:2504920311; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein; acyl carrier protein 1672592 10579923 Trebr_1414 Treponema brennaborense DSM 12168 acyl carrier protein YP_004439969.1 1672356 R 906968 CDS YP_004439970.1 332298048 10579924 complement(1672606..1672791) 1 NC_015500.1 COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: tde:TDE1025 50S ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; IMG reference gene:2504920312; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; 50S ribosomal protein L32 1672791 10579924 Trebr_1415 Treponema brennaborense DSM 12168 50S ribosomal protein L32 YP_004439970.1 1672606 R 906968 CDS YP_004439971.1 332298049 10579925 complement(1672944..1673423) 1 NC_015500.1 COGs: COG0669 Phosphopantetheine adenylyltransferase; HAMAP: Coenzyme A biosynthesis protein; InterPro IPR001980:IPR004820:IPR004821; KEGG: tde:TDE1375 pantetheine-phosphate adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: Coenzyme A biosynthesis protein; Cytidyltransferase-related; IMG reference gene:2504920313; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain; Phosphopantetheine adenylyltransferase 1673423 10579925 Trebr_1416 Treponema brennaborense DSM 12168 Phosphopantetheine adenylyltransferase YP_004439971.1 1672944 R 906968 CDS YP_004439972.1 332298050 10579926 1673480..1674061 1 NC_015500.1 KEGG: tde:TDE2350 lipoprotein; SPTR: lipoprotein; IMG reference gene:2504920314; lipoprotein 1674061 10579926 Trebr_1417 Treponema brennaborense DSM 12168 lipoprotein YP_004439972.1 1673480 D 906968 CDS YP_004439973.1 332298051 10579927 1674124..1674828 1 NC_015500.1 KEGG: tde:TDE2349 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920315; hypothetical protein 1674828 10579927 Trebr_1418 Treponema brennaborense DSM 12168 hypothetical protein YP_004439973.1 1674124 D 906968 CDS YP_004439974.1 332298052 10579929 1675036..1675629 1 NC_015500.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; HAMAP: Maf-like protein; InterPro IPR003697; KEGG: dal:Dalk_0395 maf protein; PFAM: Maf-like protein; SPTR: Maf-like protein TREVI0001_0108; TIGRFAM: Maf-like protein; IMG reference gene:2504920317; PFAM: Maf-like protein; TIGRFAM: MAF protein; Septum formation protein Maf 1675629 10579929 Trebr_1419 Treponema brennaborense DSM 12168 Septum formation protein Maf YP_004439974.1 1675036 D 906968 CDS YP_004439975.1 332298053 10579930 1675789..1676655 1 NC_015500.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005706; KEGG: tde:TDE2347 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; IMG reference gene:2504920318; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; 30S ribosomal protein S2 1676655 10579930 Trebr_1420 Treponema brennaborense DSM 12168 30S ribosomal protein S2 YP_004439975.1 1675789 D 906968 CDS YP_004439976.1 332298054 10579931 1676813..1677649 1 NC_015500.1 COGs: COG0264 Translation elongation factor Ts; HAMAP: Elongation factor Ts; InterPro IPR000449:IPR014039:IPR001816; KEGG: tde:TDE2346 elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B, dimerisation; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; SPTR: Elongation factor Ts; TIGRFAM: Translation elongation factor EFTs/EF1B; IMG reference gene:2504920319; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts; elongation factor Ts 1677649 10579931 Trebr_1421 Treponema brennaborense DSM 12168 elongation factor Ts YP_004439976.1 1676813 D 906968 CDS YP_004439977.1 332298055 10579932 1677739..1678290 1 NC_015500.1 COGs: COG0233 Ribosome recycling factor; HAMAP: Ribosome recycling factor, bacterial-like; InterPro IPR015998:IPR002661; KEGG: tde:TDE2345 ribosome recycling factor; PFAM: Ribosome recycling factor; SPTR: Ribosome-recycling factor; TIGRFAM: Ribosome recycling factor; IMG reference gene:2504920320; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor; Ribosome-recycling factor 1678290 10579932 Trebr_1422 Treponema brennaborense DSM 12168 Ribosome-recycling factor YP_004439977.1 1677739 D 906968 CDS YP_004439978.1 332298056 10579933 1678290..1678994 1 NC_015500.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; HAMAP: Undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: sta:STHERM_c13090 undecaprenyl pyrophosphate synthetase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Undecaprenyl pyrophosphate synthetase; TIGRFAM:Di-trans-poly-cis-decaprenylcistransferase- like; IMG reference gene:2504920321; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; UDP pyrophosphate synthase 1678994 10579933 Trebr_1423 Treponema brennaborense DSM 12168 UDP pyrophosphate synthase YP_004439978.1 1678290 D 906968 CDS YP_004439979.1 332298057 10579934 1679007..1679867 1 NC_015500.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: tde:TDE2343 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; IMG reference gene:2504920322; PFAM: Cytidylyltransferase family; phosphatidate cytidylyltransferase 1679867 10579934 Trebr_1424 Treponema brennaborense DSM 12168 phosphatidate cytidylyltransferase YP_004439979.1 1679007 D 906968 CDS YP_004439980.1 332298058 10579935 1679871..1681007 1 NC_015500.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; HAMAP: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512:IPR013644:IPR003821; KEGG: tde:TDE2342 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal; 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; IMG reference gene:2504920323; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1681007 10579935 Trebr_1425 Treponema brennaborense DSM 12168 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004439980.1 1679871 D 906968 CDS YP_004439981.1 332298059 10579936 1681004..1682338 1 NC_015500.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR001478:IPR008915:IPR004387; KEGG: tde:TDE2341 membrane-associated zinc metalloprotease, PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: RIP metalloprotease RseP; TIGRFAM: Peptidase M50, membrane-associated zinc metallopeptidase; IMG reference gene:2504920324; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP; membrane-associated zinc metalloprotease 1682338 10579936 Trebr_1426 Treponema brennaborense DSM 12168 membrane-associated zinc metalloprotease YP_004439981.1 1681004 D 906968 CDS YP_004439982.1 332298060 10579937 1682347..1684272 1 NC_015500.1 KEGG: tde:TDE2184 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920325; hypothetical protein 1684272 10579937 Trebr_1427 Treponema brennaborense DSM 12168 hypothetical protein YP_004439982.1 1682347 D 906968 CDS YP_004439983.1 332298061 10579938 complement(1684427..1685755) 1 NC_015500.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR003593:IPR007693:IPR007694:IPR007692; KEGG: ssm:Spirs_2874 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Replicative DNA helicase; TIGRFAM: DNA helicase, DnaB type; IMG reference gene:2504920326; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; replicative DNA helicase 1685755 10579938 Trebr_1428 Treponema brennaborense DSM 12168 replicative DNA helicase YP_004439983.1 1684427 R 906968 CDS YP_004439984.1 332298062 10579939 complement(1685759..1686304) 1 NC_015500.1 COGs: COG0359 Ribosomal protein L9; HAMAP: Ribosomal protein L9, bacteria/chloroplast; InterPro IPR020594:IPR020070:IPR020069; KEGG: tde:TDE1675 50S ribosomal protein L9; PFAM: Ribosomal protein L9, N-terminal; Ribosomal protein L9, C-terminal; SPTR: 50S ribosomal protein L9; TIGRFAM: Ribosomal protein L9, bacteria/chloroplast; IMG reference gene:2504920327; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9; 50S ribosomal protein L9 1686304 10579939 Trebr_1429 Treponema brennaborense DSM 12168 50S ribosomal protein L9 YP_004439984.1 1685759 R 906968 CDS YP_004439985.1 332298063 10579940 complement(1686398..1686709) 1 NC_015500.1 COGs: COG0238 Ribosomal protein S18; HAMAP: 30S ribosomal protein S18; InterPro IPR001648; KEGG: tde:TDE1676 30S ribosomal protein S18; PFAM: Ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: Ribosomal protein S18; IMG reference gene:2504920328; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18; 30S ribosomal protein S18 1686709 10579940 Trebr_1430 Treponema brennaborense DSM 12168 30S ribosomal protein S18 YP_004439985.1 1686398 R 906968 CDS YP_004439986.1 332298064 10579941 complement(1686749..1687258) 1 NC_015500.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: tde:TDE1677 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504920329; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein 1687258 10579941 Trebr_1431 Treponema brennaborense DSM 12168 single-strand binding protein YP_004439986.1 1686749 R 906968 CDS YP_004439987.1 332298065 10579942 complement(1687280..1687561) 1 NC_015500.1 COGs: COG0360 Ribosomal protein S6; HAMAP: Ribosomal protein S6, bacterial-like; InterPro IPR020814:IPR000529; KEGG: tde:TDE1678 30S ribosomal protein S6; PFAM: Ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: Ribosomal protein S6; IMG reference gene:2504920330; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6; 30S ribosomal protein S6 1687561 10579942 Trebr_1432 Treponema brennaborense DSM 12168 30S ribosomal protein S6 YP_004439987.1 1687280 R 906968 CDS YP_004439988.1 332298066 10579943 1687762..1690425 1 NC_015500.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR015413:IPR013155:IPR002302; KEGG: tde:TDE2339 leucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Leucine--tRNA ligase; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; IMG reference gene:2504920331; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; leucyl-tRNA synthetase 1690425 10579943 Trebr_1433 Treponema brennaborense DSM 12168 leucyl-tRNA synthetase YP_004439988.1 1687762 D 906968 CDS YP_004439989.1 332298067 10579944 1690454..1691416 1 NC_015500.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: tde:TDE0634 cation efflux family protein; PFAM: Cation efflux protein; SPTR: Cation efflux family protein; TIGRFAM: Cation efflux protein; IMG reference gene:2504920332; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 1691416 10579944 Trebr_1434 Treponema brennaborense DSM 12168 cation diffusion facilitator family transporter YP_004439989.1 1690454 D 906968 CDS YP_004439990.1 332298068 10579945 complement(1691498..1692355) 1 NC_015500.1 COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: tde:TDE0633 D-alanyl-D-alanine carboxypeptidase, PFAM: Peptidase M15B/M15C, D,D-carboxypeptidase VanY/endolysins; SPTR: Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; IMG reference gene:2504920333; PFAM: D-alanyl-D-alanine carboxypeptidase; peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin 1692355 10579945 Trebr_1435 Treponema brennaborense DSM 12168 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin YP_004439990.1 1691498 R 906968 CDS YP_004439991.1 332298069 10579946 complement(1692360..1692686) 1 NC_015500.1 InterPro IPR002645; KEGG: tde:TDE0632 anti-anti-sigma factor; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; IMG reference gene:2504920334; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; sulfate transporter/antisigma-factor antagonist STAS 1692686 10579946 Trebr_1436 Treponema brennaborense DSM 12168 sulfate transporter/antisigma-factor antagonist STAS YP_004439991.1 1692360 R 906968 CDS YP_004439992.1 332298070 10579947 complement(1692905..1695046) 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR010822; KEGG: tde:TDE0631 sigma factor regulatory protein, PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-related; SPTR: Sigma factor regulatory protein, ; IMG reference gene:2504920335; PFAM: Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 1695046 10579947 Trebr_1437 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase YP_004439992.1 1692905 R 906968 CDS YP_004439993.1 332298071 10579948 complement(1695053..1696435) 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR010822; KEGG: tde:TDE0630 sigma factor regulatory protein, PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-related; SPTR: Sigma factor regulatory protein, ; IMG reference gene:2504920336; PFAM: Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 1696435 10579948 Trebr_1438 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase YP_004439993.1 1695053 R 906968 CDS YP_004439994.1 332298072 10579949 1696591..1698171 1 NC_015500.1 IMG reference gene:2504920337; PFAM: Erythromycin esterase; hypothetical protein 1698171 10579949 Trebr_1439 Treponema brennaborense DSM 12168 hypothetical protein YP_004439994.1 1696591 D 906968 CDS YP_004439995.1 332298073 10579950 complement(1698396..1699406) 1 NC_015500.1 KEGG: hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920338; hypothetical protein 1699406 10579950 Trebr_1440 Treponema brennaborense DSM 12168 hypothetical protein YP_004439995.1 1698396 R 906968 CDS YP_004439996.1 332298074 10579951 complement(1699421..1700122) 1 NC_015500.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; KEGG: ere:EUBREC_2146 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920339; hypothetical protein 1700122 10579951 Trebr_1441 Treponema brennaborense DSM 12168 hypothetical protein YP_004439996.1 1699421 R 906968 CDS YP_004439997.1 332298075 10579952 complement(1700337..1701491) 1 NC_015500.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; KEGG: mrb:Mrub_2159 glycosyltransferase 28 domain-containing protein; SPTR: Glycosyltransferase family 28 domain protein; IMG reference gene:2504920340; PFAM: Glycosyltransferase family 28 C-terminal domain; Monogalactosyldiacylglycerol (MGDG) synthase; glycosyl transferase family protein 1701491 10579952 Trebr_1442 Treponema brennaborense DSM 12168 glycosyl transferase family protein YP_004439997.1 1700337 R 906968 CDS YP_004439998.1 332298076 10579953 complement(1701618..1702835) 1 NC_015500.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: clo:HMPREF0868_0510 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; PRIAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; IMG reference gene:2504920341; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase 1702835 10579953 Trebr_1443 Treponema brennaborense DSM 12168 N-acylglucosamine 2-epimerase YP_004439998.1 1701618 R 906968 CDS YP_004439999.1 332298077 10579954 complement(1702857..1703780) 1 NC_015500.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: bhy:BHWA1_01223 N-acetylneuraminate lyase; PFAM: Dihydrodipicolinate synthetase; PRIAM: N-acetylneuraminate lyase; SPTR: uncharacterized protein; IMG reference gene:2504920342; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: N-acetylneuraminate lyase; N-acetylneuraminate lyase 1703780 10579954 Trebr_1444 Treponema brennaborense DSM 12168 N-acetylneuraminate lyase YP_004439999.1 1702857 R 906968 CDS YP_004440000.1 332298078 10579955 complement(1703786..1704634) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sak:SAK_0069 carbohydrate ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Inner membrane binding protein; IMG reference gene:2504920343; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1704634 10579955 Trebr_1445 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440000.1 1703786 R 906968 CDS YP_004440001.1 332298079 10579956 complement(1704690..1705619) 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_6205 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease protein; IMG reference gene:2504920344; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1705619 10579956 Trebr_1446 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440001.1 1704690 R 906968 CDS YP_004440002.1 332298080 10579957 complement(1705732..1707045) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tde:TDE1283 extracellular solute-binding lipoprotein, PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Bacterial extracellular solute-binding protein; IMG reference gene:2504920345; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 1707045 10579957 Trebr_1447 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440002.1 1705732 R 906968 CDS YP_004440003.1 332298081 10579958 1707286..1707942 1 NC_015500.1 COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: dae:Dtox_0202 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504920346; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 1707942 10579958 Trebr_1448 Treponema brennaborense DSM 12168 GntR family transcriptional regulator YP_004440003.1 1707286 D 906968 CDS YP_004440004.1 332298082 10579960 complement(1708199..1710244) 1 NC_015500.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 004540:IPR005225; KEGG: tde:TDE0285 elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 2; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; IMG reference gene:2504920348; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; translation elongation factor G 1710244 10579960 Trebr_1449 Treponema brennaborense DSM 12168 translation elongation factor G YP_004440004.1 1708199 R 906968 CDS YP_004440005.1 332298083 10579961 complement(1710349..1710807) 1 NC_015500.1 COGs: COG3708 conserved hypothetical protein; InterPro IPR010499; KEGG: cbt:CLH_3132 transcriptional regulator, AraC family; PFAM: Bacterial transcription activator, effector binding; SPTR: uncharacterized protein; IMG reference gene:2504920349; PFAM: Bacterial transcription activator, effector binding domain; transcription activator effector binding protein 1710807 10579961 Trebr_1450 Treponema brennaborense DSM 12168 transcription activator effector binding protein YP_004440005.1 1710349 R 906968 CDS YP_004440006.1 332298084 10579962 complement(1710994..1712715) 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR003439; KEGG: efa:EF0584 ABC transporter, ATP-binding/permease protein; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; IMG reference gene:2504920350; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 1712715 10579962 Trebr_1451 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004440006.1 1710994 R 906968 CDS YP_004440007.1 332298085 10579963 complement(1712712..1714457) 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: fma:FMG_1403 multidrug ABC transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; IMG reference gene:2504920351; PFAM: ABC transporter; ABC transporter transmembrane region; xenobiotic-transporting ATPase 1714457 10579963 Trebr_1452 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004440007.1 1712712 R 906968 CDS YP_004440008.1 332298086 10579964 1714669..1715658 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: fma:FMG_1404 transcriptional regulator; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; IMG reference gene:2504920352; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1715658 10579964 Trebr_1453 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004440008.1 1714669 D 906968 CDS YP_004440009.1 332298087 10579965 1715745..1715963 1 NC_015500.1 HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: tpp:TPASS_0758 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; IMG reference gene:2504920353; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; 30S ribosomal protein S21 1715963 10579965 Trebr_1454 Treponema brennaborense DSM 12168 30S ribosomal protein S21 YP_004440009.1 1715745 D 906968 CDS YP_004440010.1 332298088 10579966 1715964..1716881 1 NC_015500.1 KEGG: tde:TDE0635 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920354; hypothetical protein 1716881 10579966 Trebr_1455 Treponema brennaborense DSM 12168 hypothetical protein YP_004440010.1 1715964 D 906968 CDS YP_004440011.1 332298089 10579967 1716914..1717714 1 NC_015500.1 InterPro IPR009875; KEGG: sta:STHERM_c07760 hypothetical protein; PFAM: Type IV pilus assembly PilZ; SPTR: uncharacterized protein; IMG reference gene:2504920355; PFAM: PilZ domain; type IV pilus assembly PilZ 1717714 10579967 Trebr_1456 Treponema brennaborense DSM 12168 type IV pilus assembly PilZ YP_004440011.1 1716914 D 906968 CDS YP_004440012.1 332298090 10579968 1717991..1719130 1 NC_015500.1 InterPro IPR019734:IPR001440:IPR013105; KEGG: tde:TDE0213 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920356; PFAM: Coatomer epsilon subunit; hypothetical protein 1719130 10579968 Trebr_1457 Treponema brennaborense DSM 12168 hypothetical protein YP_004440012.1 1717991 D 906968 CDS YP_004440013.1 332298091 10579969 complement(1719172..1719615) 1 NC_015500.1 COGs: COG1430 conserved hypothetical protein; InterPro IPR003795; KEGG: coc:Coch_1289 protein of unknown function DUF192; PFAM: Protein of unknown function DUF192; SPTR: Lipoprotein; IMG reference gene:2504920357; PFAM: Uncharacterized ACR, COG1430; hypothetical protein 1719615 10579969 Trebr_1458 Treponema brennaborense DSM 12168 hypothetical protein YP_004440013.1 1719172 R 906968 CDS YP_004440014.1 332298092 10579970 complement(1719630..1720175) 1 NC_015500.1 KEGG: tde:TDE0066 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920358; hypothetical protein 1720175 10579970 Trebr_1459 Treponema brennaborense DSM 12168 hypothetical protein YP_004440014.1 1719630 R 906968 CDS YP_004440015.1 332298093 10579971 complement(1720184..1721365) 1 NC_015500.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: tde:TDE0067 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; IMG reference gene:2504920359; PFAM: Cyclic nucleotide-binding domain; CarD family transcriptional regulator 1721365 10579971 Trebr_1460 Treponema brennaborense DSM 12168 CarD family transcriptional regulator YP_004440015.1 1720184 R 906968 CDS YP_004440016.1 332298094 10579972 complement(1721461..1722558) 1 NC_015500.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; HAMAP: UDP-N-acetylenolpyruvoylglucosamine reductase; InterPro IPR003170:IPR006094:IPR011601; KEGG: tde:TDE0093 UDP-N-acetylenolpyruvoylglucosamine reductase, PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; IMG reference gene:2504920360; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; UDP-N-acetylenolpyruvoylglucosamine reductase 1722558 10579972 Trebr_1461 Treponema brennaborense DSM 12168 UDP-N-acetylenolpyruvoylglucosamine reductase YP_004440016.1 1721461 R 906968 CDS YP_004440017.1 332298095 10579973 1722615..1724108 1 NC_015500.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308; KEGG: tde:TDE0092 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; IMG reference gene:2504920361; PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1724108 10579973 Trebr_1462 Treponema brennaborense DSM 12168 cysteinyl-tRNA synthetase YP_004440017.1 1722615 D 906968 CDS YP_004440018.1 332298096 10579974 1724143..1724700 1 NC_015500.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: tde:TDE0091 RNA polymerase sigma-24 factor, PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504920362; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 1724700 10579974 Trebr_1463 Treponema brennaborense DSM 12168 ECF subfamily RNA polymerase sigma-24 subunit YP_004440018.1 1724143 D 906968 CDS YP_004440019.1 332298097 10579975 1724684..1725403 1 NC_015500.1 KEGG: tde:TDE0090 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920363; hypothetical protein 1725403 10579975 Trebr_1464 Treponema brennaborense DSM 12168 hypothetical protein YP_004440019.1 1724684 D 906968 CDS YP_004440020.1 332298098 10579976 1725403..1727094 1 NC_015500.1 COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931:IPR002909; KEGG: tde:TDE0089 transglutaminase-like domain-containing protein; PFAM: Transglutaminase-like; Cell surface receptor IPT/TIG; SMART: Transglutaminase-like; SPTR: uncharacterized protein; IMG reference gene:2504920364; PFAM: Transglutaminase-like superfamily; IPT/TIG domain; transglutaminase domain-containing protein 1727094 10579976 Trebr_1465 Treponema brennaborense DSM 12168 transglutaminase domain-containing protein YP_004440020.1 1725403 D 906968 CDS YP_004440021.1 332298099 10579977 1727124..1727819 1 NC_015500.1 COGs: COG0528 Uridylate kinase; InterPro IPR001048:IPR011818; KEGG: tde:TDE2085 uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Amino acid kinase family protein; TIGRFAM: Uridylate kinase, archaeal/spirochete, IMG reference gene:2504920365; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase; uridylate kinase 1727819 10579977 Trebr_1466 Treponema brennaborense DSM 12168 uridylate kinase YP_004440021.1 1727124 D 906968 CDS YP_004440022.1 332298100 10579978 complement(1727918..1728520) 1 NC_015500.1 KEGG: tde:TDE0488 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504920366; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; hypothetical protein 1728520 10579978 Trebr_1467 Treponema brennaborense DSM 12168 hypothetical protein YP_004440022.1 1727918 R 906968 CDS YP_004440023.1 332298101 10579979 1728620..1729285 1 NC_015500.1 COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: nde:NIDE2507 DNA repair protein RadC-like protein; PFAM: DNA repair, RadC-like; SPTR: DNA repair protein RadC homolog; TIGRFAM: DNA repair, RadC-like; IMG reference gene:2504920367; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; DNA repair protein RadC 1729285 10579979 Trebr_1468 Treponema brennaborense DSM 12168 DNA repair protein RadC YP_004440023.1 1728620 D 906968 CDS YP_004440024.1 332298102 10579980 complement(1729320..1730504) 1 NC_015500.1 KEGG: tde:TDE2244 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920368; hypothetical protein 1730504 10579980 Trebr_1469 Treponema brennaborense DSM 12168 hypothetical protein YP_004440024.1 1729320 R 906968 CDS YP_004440025.1 332298103 10579981 1730647..1731681 1 NC_015500.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: cbe:Cbei_3974 aldo/keto reductase; PFAM: Aldo/keto reductase; SPTR: Aldo/keto reductase; IMG reference gene:2504920369; PFAM: Aldo/keto reductase family; aldo/keto reductase 1731681 10579981 Trebr_1470 Treponema brennaborense DSM 12168 aldo/keto reductase YP_004440025.1 1730647 D 906968 CDS YP_004440026.1 332298104 10579982 1731681..1732589 1 NC_015500.1 COGs: COG2961 Protein involved in catabolism of external DNA; InterPro IPR007473; KEGG: ecl:EcolC_0217 hypothetical protein; PFAM: Protein of unknown function DUF519; SPTR: DNA (Exogenous) processing protein; IMG reference gene:2504920370; PFAM: Protein of unknown function (DUF519); hypothetical protein 1732589 10579982 Trebr_1471 Treponema brennaborense DSM 12168 hypothetical protein YP_004440026.1 1731681 D 906968 CDS YP_004440027.1 332298105 10579983 complement(1732598..1735195) 1 NC_015500.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR013093:IPR 019489:IPR017730; KEGG: bpo:BP951000_2092 ATP-dependent Clp protease ATP-binding subunit ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: Chaperonin ClpB; IMG reference gene:2504920371; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; ATP-dependent chaperone ClpB 1735195 10579983 Trebr_1472 Treponema brennaborense DSM 12168 ATP-dependent chaperone ClpB YP_004440027.1 1732598 R 906968 CDS YP_004440028.1 332298106 10579984 complement(1735295..1736344) 1 NC_015500.1 KEGG: ccb:Clocel_0502 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920372; hypothetical protein 1736344 10579984 Trebr_1473 Treponema brennaborense DSM 12168 hypothetical protein YP_004440028.1 1735295 R 906968 CDS YP_004440029.1 332298107 10579985 complement(1736417..1736629) 1 NC_015500.1 IMG reference gene:2504920373; hypothetical protein 1736629 10579985 Trebr_1474 Treponema brennaborense DSM 12168 hypothetical protein YP_004440029.1 1736417 R 906968 CDS YP_004440030.1 332298108 10579986 complement(1736667..1739804) 1 NC_015500.1 COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765:IPR007863:IPR013578; KEGG: tde:TDE1865 M16 family peptidase; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase, M16 family; IMG reference gene:2504920374; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Peptidase M16C associated domain-containing protein 1739804 10579986 Trebr_1475 Treponema brennaborense DSM 12168 Peptidase M16C associated domain-containing protein YP_004440030.1 1736667 R 906968 CDS YP_004440031.1 332298109 10579987 1740175..1741857 1 NC_015500.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005668; KEGG: caa:Caka_1596 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: 2-isopropylmalate synthase; SPTR: 2-isopropylmalate synthase; TIGRFAM: Yeast 2-isopropylmalate synthase; IMG reference gene:2504920375; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase, yeast type; 2-isopropylmalate synthase 1741857 10579987 Trebr_1476 Treponema brennaborense DSM 12168 2-isopropylmalate synthase YP_004440031.1 1740175 D 906968 CDS YP_004440032.1 332298110 10579991 1742541..1743095 1 NC_015500.1 IMG reference gene:2504920379; hypothetical protein 1743095 10579991 Trebr_1477 Treponema brennaborense DSM 12168 hypothetical protein YP_004440032.1 1742541 D 906968 CDS YP_004440033.1 332298111 10579992 1743103..1743825 1 NC_015500.1 InterPro IPR000792; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; SPTR: Sigma-70, region 4 family; manually curated; IMG reference gene:2504920380; PFAM: Bacterial regulatory proteins, luxR family; regulatory protein LuxR 1743825 10579992 Trebr_1478 Treponema brennaborense DSM 12168 regulatory protein LuxR YP_004440033.1 1743103 D 906968 CDS YP_004440034.1 332298112 10579993 1744296..1744913 1 NC_015500.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; HAMAP: Holliday junction ATP-dependent DNA helicase ruvA; InterPro IPR003583:IPR013849:IPR000085; KEGG: tde:TDE1863 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Bacterial DNA recombination protein RuvA; IMG reference gene:2504920381; PFAM: RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit; Holliday junction ATP-dependent DNA helicase ruvA 1744913 10579993 Trebr_1479 Treponema brennaborense DSM 12168 Holliday junction ATP-dependent DNA helicase ruvA YP_004440034.1 1744296 D 906968 CDS YP_004440035.1 332298113 10579994 1744915..1745934 1 NC_015500.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; HAMAP: DNA helicase, Holliday junction RuvB type; InterProIPR003593:IPR004605:IPR008824:IPR003959:IPR 008823; KEGG: tde:TDE1914 Holliday junction DNA helicase RuvB; PFAM: DNA helicase, Holliday junction RuvB type, C-terminal; ATPase, AAA-type, core; DNA helicase, Holliday junction RuvB type, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: DNA helicase, Holliday junction RuvB type; IMG reference gene:2504920382; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit; Holliday junction ATP-dependent DNA helicase ruvB 1745934 10579994 Trebr_1480 Treponema brennaborense DSM 12168 Holliday junction ATP-dependent DNA helicase ruvB YP_004440035.1 1744915 D 906968 CDS YP_004440036.1 332298114 10579995 1745909..1746946 1 NC_015500.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); HAMAP: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; InterPro IPR003699; KEGG: tde:TDE2451 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; TIGRFAM: Queuosine biosynthesis protein; IMG reference gene:2504920383; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; S-adenosylmethionine:tRNAribosyltransferase- isomerase 1746946 10579995 Trebr_1481 Treponema brennaborense DSM 12168 S-adenosylmethionine:tRNAribosyltransferase- isomerase YP_004440036.1 1745909 D 906968 CDS YP_004440037.1 332298115 10579996 1747047..1747589 1 NC_015500.1 COGs: COG1592 Rubrerythrin; InterPro IPR004039:IPR003251; KEGG: fsu:Fisuc_1486 rubrerythrin; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: uncharacterized protein; IMG reference gene:2504920384; PFAM: Rubrerythrin; rubrerythrin 1747589 10579996 Trebr_1482 Treponema brennaborense DSM 12168 rubrerythrin YP_004440037.1 1747047 D 906968 CDS YP_004440038.1 332298116 10579997 1747731..1748171 1 NC_015500.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: csc:Csac_2429 ferric uptake regulator family protein; PFAM: Ferric-uptake regulator; SPTR: Fe2+/Zn2+ uptake regulation protein; IMG reference gene:2504920385; PFAM: Ferric uptake regulator family; ferric uptake regulator, Fur family 1748171 10579997 Trebr_1483 Treponema brennaborense DSM 12168 ferric uptake regulator, Fur family YP_004440038.1 1747731 D 906968 CDS YP_004440039.1 332298117 10579998 1748305..1751127 1 NC_015500.1 COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: tde:TDE2693 ankyrin repeateat-containing protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin repeat protein; IMG reference gene:2504920386; PFAM: Ankyrin repeat; ankyrin 1751127 10579998 Trebr_1484 Treponema brennaborense DSM 12168 ankyrin YP_004440039.1 1748305 D 906968 CDS YP_004440040.1 332298118 10579999 complement(1751191..1751484) 1 NC_015500.1 InterPro IPR000831:IPR013335; KEGG: ssm:Spirs_1491 Trp repressor; PFAM: Trp repressor; SPTR: Trp repressor; TIGRFAM: Trp repressor, bacterial; IMG reference gene:2504920387; PFAM: Trp repressor protein; TIGRFAM: trp operon repressor, proteobacterial; trp operon repressor 1751484 10579999 Trebr_1485 Treponema brennaborense DSM 12168 trp operon repressor YP_004440040.1 1751191 R 906968 CDS YP_004440041.1 332298119 10580000 1751533..1751778 1 NC_015500.1 KEGG: ppd:Ppro_2932 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920388; hypothetical protein 1751778 10580000 Trebr_1486 Treponema brennaborense DSM 12168 hypothetical protein YP_004440041.1 1751533 D 906968 CDS YP_004440042.1 332298120 10580001 complement(1751904..1752947) 1 NC_015500.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130; KEGG: tde:TDE2029 TatD family hydrolase; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; IMG reference gene:2504920389; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; TatD-related deoxyribonuclease 1752947 10580001 Trebr_1487 Treponema brennaborense DSM 12168 TatD-related deoxyribonuclease YP_004440042.1 1751904 R 906968 CDS YP_004440043.1 332298121 10580004 complement(1753380..1755170) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: mgm:Mmc1_1479 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504920392; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1755170 10580004 Trebr_1488 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440043.1 1753380 R 906968 CDS YP_004440044.1 332298122 10580005 complement(1755175..1756947) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: alv:Alvin_0595 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer; IMG reference gene:2504920393; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1756947 10580005 Trebr_1489 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440044.1 1755175 R 906968 CDS YP_004440045.1 332298123 10580006 complement(1756974..1758815) 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: sta:STHERM_c01070 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Signal transduction response regulator, receiver region; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; Signal transduction response regulator, receiver region; SPTR: Adenylate cyclase; IMG reference gene:2504920394; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; adenylate/guanylate cyclase 1758815 10580006 Trebr_1490 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase YP_004440045.1 1756974 R 906968 CDS YP_004440046.1 332298124 10580007 complement(1758808..1760898) 1 NC_015500.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: mgm:Mmc1_1482 CheA signal transduction histidine kinases; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SPTR: CheA signal transduction histidine kinases; IMG reference gene:2504920395; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; CheA signal transduction histidine kinase 1760898 10580007 Trebr_1491 Treponema brennaborense DSM 12168 CheA signal transduction histidine kinase YP_004440046.1 1758808 R 906968 CDS YP_004440047.1 332298125 10580008 complement(1760914..1762206) 1 NC_015500.1 COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: dal:Dalk_1591 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase, CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type; IMG reference gene:2504920396; PFAM: CheR methyltransferase, SAM binding domain; CheR-type MCP methyltransferase 1762206 10580008 Trebr_1492 Treponema brennaborense DSM 12168 CheR-type MCP methyltransferase YP_004440047.1 1760914 R 906968 CDS YP_004440048.1 332298126 10580009 complement(1762199..1763311) 1 NC_015500.1 COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: pol:Bpro_2467 response regulator receiver (CheY-like) modulated CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: Response regulator receiver (CheY-like) modulated CheB methylesterase; IMG reference gene:2504920397; PFAM: CheB methylesterase; CheB methylesterase 1763311 10580009 Trebr_1493 Treponema brennaborense DSM 12168 CheB methylesterase YP_004440048.1 1762199 R 906968 CDS YP_004440049.1 332298127 10580010 complement(1763314..1763700) 1 NC_015500.1 IMG reference gene:2504920398; hypothetical protein 1763700 10580010 Trebr_1494 Treponema brennaborense DSM 12168 hypothetical protein YP_004440049.1 1763314 R 906968 CDS YP_004440050.1 332298128 10580011 complement(1763756..1764247) 1 NC_015500.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: cce:Ccel_2099 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein; IMG reference gene:2504920399; PFAM: CheW-like domain; CheW protein 1764247 10580011 Trebr_1495 Treponema brennaborense DSM 12168 CheW protein YP_004440050.1 1763756 R 906968 CDS YP_004440051.1 332298129 10580012 complement(1764546..1765673) 1 NC_015500.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone protein dnaJ; InterPro IPR001623:IPR001305:IPR002939:IPR012724; KEGG: ssm:Spirs_3197 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich region; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein DnaJ; TIGRFAM: Chaperone DnaJ; IMG reference gene:2504920400; PFAM: DnaJ central domain (4 repeats); DnaJ domain; DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ; chaperone protein dnaJ 1765673 10580012 Trebr_1496 Treponema brennaborense DSM 12168 chaperone protein dnaJ YP_004440051.1 1764546 R 906968 CDS YP_004440052.1 332298130 10580013 complement(1765819..1767756) 1 NC_015500.1 COGs: COG0443 Molecular chaperone; HAMAP: Chaperone DnaK; InterPro IPR012725:IPR013126; KEGG: tde:TDE0628 molecular chaperone DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: Chaperone DnaK; IMG reference gene:2504920401; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK; chaperone protein dnaK 1767756 10580013 Trebr_1497 Treponema brennaborense DSM 12168 chaperone protein dnaK YP_004440052.1 1765819 R 906968 CDS YP_004440053.1 332298131 10580014 complement(1767806..1768471) 1 NC_015500.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); HAMAP: GrpE nucleotide exchange factor; InterPro IPR000740; KEGG: tde:TDE0627 co-chaperone protein GrpE; PFAM: GrpE nucleotide exchange factor; SPTR: Protein grpE; IMG reference gene:2504920402; PFAM: GrpE; protein grpE 1768471 10580014 Trebr_1498 Treponema brennaborense DSM 12168 protein grpE YP_004440053.1 1767806 R 906968 CDS YP_004440054.1 332298132 10580016 complement(1769608..1770645) 1 NC_015500.1 COGs: COG2502 Asparagine synthetase A; HAMAP: Aspartate--ammonia ligase; InterPro IPR004618; KEGG: pru:PRU_1711 aspartate--ammonia ligase; PFAM: Aspartate--ammonia ligase; PRIAM: Aspartate--ammonia ligase; SPTR: Aspartate--ammonia ligase; TIGRFAM: Aspartate--ammonia ligase; IMG reference gene:2504920404; PFAM: Aspartate-ammonia ligase; TIGRFAM: aspartate--ammonia ligase, AsnA-type; Aspartate--ammonia ligase 1770645 10580016 Trebr_1500 Treponema brennaborense DSM 12168 Aspartate--ammonia ligase YP_004440054.1 1769608 R 906968 CDS YP_004440055.1 332298133 10580017 1770853..1772985 1 NC_015500.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: tde:TDE0903 ATP-dependent DNA helicase PcrA; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase PcrA; IMG reference gene:2504920405; PFAM: UvrD/REP helicase; UvrD/REP helicase 1772985 10580017 Trebr_1501 Treponema brennaborense DSM 12168 UvrD/REP helicase YP_004440055.1 1770853 D 906968 CDS YP_004440056.1 332298134 10580018 1773161..1773298 1 NC_015500.1 IMG reference gene:2504920406; hypothetical protein 1773298 10580018 Trebr_1502 Treponema brennaborense DSM 12168 hypothetical protein YP_004440056.1 1773161 D 906968 CDS YP_004440057.1 332298135 10580019 1773395..1774180 1 NC_015500.1 KEGG: dal:Dalk_4949 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920407; hypothetical protein 1774180 10580019 Trebr_1503 Treponema brennaborense DSM 12168 hypothetical protein YP_004440057.1 1773395 D 906968 CDS YP_004440058.1 332298136 10580020 1774196..1775488 1 NC_015500.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280; KEGG: tde:TDE2619 RNA methyltransferase; PFAM: Deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; SPTR: Uncharacterized RNA methyltransferase TDE_2619; IMG reference gene:2504920408; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; deoxyribonuclease/rho motif-related TRAM 1775488 10580020 Trebr_1504 Treponema brennaborense DSM 12168 deoxyribonuclease/rho motif-related TRAM YP_004440058.1 1774196 D 906968 CDS YP_004440059.1 332298137 10580021 1775485..1777263 1 NC_015500.1 KEGG: tde:TDE2698 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920409; hypothetical protein 1777263 10580021 Trebr_1505 Treponema brennaborense DSM 12168 hypothetical protein YP_004440059.1 1775485 D 906968 CDS YP_004440060.1 332298138 10580022 1777342..1778934 1 NC_015500.1 InterPro IPR007926; KEGG: tde:TDE2699 antigen, PFAM: Borrelia P83100; SPTR: Antigen, ; IMG reference gene:2504920410; PFAM: Borrelia P83/100 protein; P83100 family protein 1778934 10580022 Trebr_1506 Treponema brennaborense DSM 12168 P83100 family protein YP_004440060.1 1777342 D 906968 CDS YP_004440061.1 332298139 10580023 complement(1778992..1779462) 1 NC_015500.1 InterPro IPR004360; KEGG: dsy:DSY0048 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; IMG reference gene:2504920411; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; glyoxalase/bleomycin resistance protein/dioxygenase 1779462 10580023 Trebr_1507 Treponema brennaborense DSM 12168 glyoxalase/bleomycin resistance protein/dioxygenase YP_004440061.1 1778992 R 906968 CDS YP_004440062.1 332298140 10580024 complement(1779475..1780254) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060; KEGG: dsy:DSY0047 hypothetical protein; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; IMG reference gene:2504920412; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1780254 10580024 Trebr_1508 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004440062.1 1779475 R 906968 CDS YP_004440063.1 332298141 10580025 complement(1780306..1782600) 1 NC_015500.1 InterPro IPR019934; KEGG: tde:TDE1580 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP03545; IMG reference gene:2504920413; TIGRFAM: TIGR03545 family protein; hypothetical protein 1782600 10580025 Trebr_1509 Treponema brennaborense DSM 12168 hypothetical protein YP_004440063.1 1780306 R 906968 CDS YP_004440064.1 332298142 10580026 complement(1782622..1783149) 1 NC_015500.1 InterPro IPR019935; KEGG: tde:TDE1581 hypothetical protein; SPTR: Membrane protein, ; TIGRFAM: Conserved hypothetical protein CHP03546; IMG reference gene:2504920414; PFAM: Uncharacterized protein conserved in bacteria (DUF2062); TIGRFAM: TIGR03546 family protein; hypothetical protein 1783149 10580026 Trebr_1510 Treponema brennaborense DSM 12168 hypothetical protein YP_004440064.1 1782622 R 906968 CDS YP_004440065.1 332298143 10580027 complement(1783201..1784667) 1 NC_015500.1 COGs: COG0297 Glycogen synthase; HAMAP: Glycogen/starch synthases, ADP-glucose type; InterPro IPR011835:IPR013534; KEGG: tde:TDE1582 glycogen synthase; PFAM: Starch synthase catalytic region; PRIAM: Starch synthase; SPTR: Glycogen synthase; TIGRFAM: Glycogen/starch synthases, ADP-glucose type; IMG reference gene:2504920415; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type; Glycogen synthase 1784667 10580027 Trebr_1511 Treponema brennaborense DSM 12168 Glycogen synthase YP_004440065.1 1783201 R 906968 CDS YP_004440066.1 332298144 10580028 complement(1784752..1785984) 1 NC_015500.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dba:Dbac_3303 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504920416; PFAM: Aminotransferase class I and II; aspartate transaminase 1785984 10580028 Trebr_1512 Treponema brennaborense DSM 12168 aspartate transaminase YP_004440066.1 1784752 R 906968 CDS YP_004440067.1 332298145 10580029 1786272..1786997 1 NC_015500.1 IMG reference gene:2504920417; hypothetical protein 1786997 10580029 Trebr_1513 Treponema brennaborense DSM 12168 hypothetical protein YP_004440067.1 1786272 D 906968 CDS YP_004440068.1 332298146 10580030 1787008..1788111 1 NC_015500.1 COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: sta:STHERM_c01790 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase; IMG reference gene:2504920418; PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; mannose-1-phosphate guanylyltransferase 1788111 10580030 Trebr_1514 Treponema brennaborense DSM 12168 mannose-1-phosphate guanylyltransferase YP_004440068.1 1787008 D 906968 CDS YP_004440069.1 332298147 10580031 1788116..1789354 1 NC_015500.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132:IPR013974; KEGG: tde:TDE0960 NeuB family protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; SPTR: NeuB family protein; IMG reference gene:2504920419; PFAM: SAF domain; NeuB family; N-acetylneuraminic acid synthase domain-containing protein 1789354 10580031 Trebr_1515 Treponema brennaborense DSM 12168 N-acetylneuraminic acid synthase domain-containing protein YP_004440069.1 1788116 D 906968 CDS YP_004440070.1 332298148 10580032 1789461..1789925 1 NC_015500.1 COGs: COG0691 tmRNA-binding protein; HAMAP: SsrA-binding protein; InterPro IPR000037; KEGG: tde:TDE1464 SsrA-binding protein; PFAM: SsrA-binding protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; IMG reference gene:2504920420; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein; SsrA-binding protein 1789925 10580032 Trebr_1516 Treponema brennaborense DSM 12168 SsrA-binding protein YP_004440070.1 1789461 D 906968 CDS YP_004440071.1 332298149 10580033 1789928..1790791 1 NC_015500.1 KEGG: tpp:TPASS_0183 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920421; hypothetical protein 1790791 10580033 Trebr_1517 Treponema brennaborense DSM 12168 hypothetical protein YP_004440071.1 1789928 D 906968 CDS YP_004440072.1 332298150 10580034 complement(1790802..1791383) 1 NC_015500.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070; KEGG: tde:TDE1462 SUA5/YciO/YrdC/YwlC family protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Sua5/YciO/YrdC/YwlC family protein; IMG reference gene:2504920422; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; SUA5/yciO/yrdC domain-containing protein 1791383 10580034 Trebr_1518 Treponema brennaborense DSM 12168 SUA5/yciO/yrdC domain-containing protein YP_004440072.1 1790802 R 906968 CDS YP_004440073.1 332298151 10580035 complement(1791380..1791904) 1 NC_015500.1 InterPro IPR007060; KEGG: tde:TDE1461 septum formation initiator family protein; PFAM: Septum formation initiator; SPTR: Septum formation initiator family protein; IMG reference gene:2504920423; PFAM: Septum formation initiator; septum formation initiator 1791904 10580035 Trebr_1519 Treponema brennaborense DSM 12168 septum formation initiator YP_004440073.1 1791380 R 906968 CDS YP_004440074.1 332298152 10580036 1792231..1795899 1 NC_015500.1 KEGG: vpo:Kpol_1058p4 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920424; hypothetical protein 1795899 10580036 Trebr_1520 Treponema brennaborense DSM 12168 hypothetical protein YP_004440074.1 1792231 D 906968 CDS YP_004440075.1 332298153 10580037 1795901..1796770 1 NC_015500.1 IMG reference gene:2504920425; hypothetical protein 1796770 10580037 Trebr_1521 Treponema brennaborense DSM 12168 hypothetical protein YP_004440075.1 1795901 D 906968 CDS YP_004440076.1 332298154 10580038 1796776..1798329 1 NC_015500.1 COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tde:TDE1458 hypothetical protein; PFAM: Protein of unknown function DUF115; SPTR: uncharacterized protein; IMG reference gene:2504920426; PFAM: Protein of unknown function DUF115; hypothetical protein 1798329 10580038 Trebr_1522 Treponema brennaborense DSM 12168 hypothetical protein YP_004440076.1 1796776 D 906968 CDS YP_004440077.1 332298155 10580039 1798326..1799861 1 NC_015500.1 COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tde:TDE1457 hypothetical protein; PFAM: Protein of unknown function DUF115; SPTR: uncharacterized protein; IMG reference gene:2504920427; PFAM: Protein of unknown function DUF115; hypothetical protein 1799861 10580039 Trebr_1523 Treponema brennaborense DSM 12168 hypothetical protein YP_004440077.1 1798326 D 906968 CDS YP_004440078.1 332298156 10580040 1799851..1801185 1 NC_015500.1 InterPro IPR000160; KEGG: tde:TDE1456 GGDEF domain-containing protein; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF domain protein; IMG reference gene:2504920428; GGDEF domain containing protein 1801185 10580040 Trebr_1524 Treponema brennaborense DSM 12168 GGDEF domain containing protein YP_004440078.1 1799851 D 906968 CDS YP_004440079.1 332298157 10580041 complement(1801202..1801849) 1 NC_015500.1 InterPro IPR019734; KEGG: tde:TDE1613 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920429; hypothetical protein 1801849 10580041 Trebr_1525 Treponema brennaborense DSM 12168 hypothetical protein YP_004440079.1 1801202 R 906968 CDS YP_004440080.1 332298158 10580042 complement(1801858..1802931) 1 NC_015500.1 COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: tde:TDE1612 phosphoribosyl transferase domain-containing protein; SPTR: Phosphoribosyl transferase domain protein; IMG reference gene:2504920430; phosphoribosyl transferase domain-containing protein 1802931 10580042 Trebr_1526 Treponema brennaborense DSM 12168 phosphoribosyl transferase domain-containing protein YP_004440080.1 1801858 R 906968 CDS YP_004440081.1 332298159 10580043 complement(1802967..1803899) 1 NC_015500.1 IMG reference gene:2504920431; hypothetical protein 1803899 10580043 Trebr_1527 Treponema brennaborense DSM 12168 hypothetical protein YP_004440081.1 1802967 R 906968 CDS YP_004440082.1 332298160 10580044 complement(1803886..1807083) 1 NC_015500.1 COGs: COG0060 Isoleucyl-tRNA synthetase; HAMAP: Isoleucyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR002301; KEGG: tde:TDE2663 isoleucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Isoleucine--tRNA ligase; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: Isoleucyl-tRNA synthetase, class Ia; IMG reference gene:2504920432; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1807083 10580044 Trebr_1528 Treponema brennaborense DSM 12168 isoleucyl-tRNA synthetase YP_004440082.1 1803886 R 906968 CDS YP_004440083.1 332298161 10580045 complement(1807214..1808080) 1 NC_015500.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: tpp:TPASS_0343 possible A/G-specific adenine glycosylase; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein; IMG reference gene:2504920433; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; HhH-GPD family protein 1808080 10580045 Trebr_1529 Treponema brennaborense DSM 12168 HhH-GPD family protein YP_004440083.1 1807214 R 906968 CDS YP_004440084.1 332298162 10580046 complement(1808097..1808660) 1 NC_015500.1 COGs: COG1102 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR011892; KEGG: tde:TDE1087 cytidylate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase, IMG reference gene:2504920434; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; cytidylate kinase 1808660 10580046 Trebr_1530 Treponema brennaborense DSM 12168 cytidylate kinase YP_004440084.1 1808097 R 906968 CDS YP_004440085.1 332298163 10580047 complement(1808787..1811528) 1 NC_015500.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111:IPR003593:IPR003959:IPR008269:IPR 004815; KEGG: tde:TDE0670 ATP-dependent protease La; PFAM: Peptidase S16, lon C-terminal; Peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: Peptidase S16, ATP-dependent protease La; IMG reference gene:2504920435; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La; anti-sigma H sporulation factor LonB 1811528 10580047 Trebr_1531 Treponema brennaborense DSM 12168 anti-sigma H sporulation factor LonB YP_004440085.1 1808787 R 906968 CDS YP_004440086.1 332298164 10580048 complement(1811794..1813398) 1 NC_015500.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR020635:IPR002290:IPR017442; KEGG: sta:STHERM_c06970 serine/threonine-protein kinase Sps1; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: Serine/threonine-protein kinase Sps1; IMG reference gene:2504920436; PFAM: Protein kinase domain; serine/threonine protein kinase 1813398 10580048 Trebr_1532 Treponema brennaborense DSM 12168 serine/threonine protein kinase YP_004440086.1 1811794 R 906968 CDS YP_004440087.1 332298165 10580049 complement(1813424..1814461) 1 NC_015500.1 KEGG: sta:STHERM_c06960 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920437; hypothetical protein 1814461 10580049 Trebr_1533 Treponema brennaborense DSM 12168 hypothetical protein YP_004440087.1 1813424 R 906968 CDS YP_004440088.1 332298166 10580050 complement(1814487..1814831) 1 NC_015500.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: sta:STHERM_c06930 hypothetical protein; PFAM: Forkhead-associated; SMART: Forkhead-associated; SPTR: uncharacterized protein; IMG reference gene:2504920438; PFAM: FHA domain; FHA domain-containing protein 1814831 10580050 Trebr_1534 Treponema brennaborense DSM 12168 FHA domain-containing protein YP_004440088.1 1814487 R 906968 CDS YP_004440089.1 332298167 10580051 complement(1814864..1815433) 1 NC_015500.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; HAMAP: Crossover junction endodeoxyribonuclease RuvC; InterPro IPR002176; KEGG: tde:TDE1864 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC; IMG reference gene:2504920439; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; Crossover junction endodeoxyribonuclease ruvC 1815433 10580051 Trebr_1535 Treponema brennaborense DSM 12168 Crossover junction endodeoxyribonuclease ruvC YP_004440089.1 1814864 R 906968 CDS YP_004440090.1 332298168 10580052 complement(1815423..1816163) 1 NC_015500.1 COGs: COG0217 conserved hypothetical protein; HAMAP: Protein of unknown function DUF28; InterPro IPR002876; KEGG: tde:TDE1487 hypothetical protein; PFAM: Protein of unknown function DUF28; SPTR: UPF0082 protein TDE_1487; TIGRFAM: Protein of unknown function DUF28; IMG reference gene:2504920440; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family; hypothetical protein 1816163 10580052 Trebr_1536 Treponema brennaborense DSM 12168 hypothetical protein YP_004440090.1 1815423 R 906968 CDS YP_004440091.1 332298169 10580054 1816569..1817519 1 NC_015500.1 COGs: COG0078 Ornithine carbamoyltransferase; HAMAP: Ornithine carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002292; KEGG: tmt:Tmath_0595 ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase; TIGRFAM: Ornithine carbamoyltransferase; IMG reference gene:2504920442; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; ornithine carbamoyltransferase 1817519 10580054 Trebr_1537 Treponema brennaborense DSM 12168 ornithine carbamoyltransferase YP_004440091.1 1816569 D 906968 CDS YP_004440092.1 332298170 10580055 1817534..1817956 1 NC_015500.1 KEGG: tde:TDE1480 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920443; hypothetical protein 1817956 10580055 Trebr_1538 Treponema brennaborense DSM 12168 hypothetical protein YP_004440092.1 1817534 D 906968 CDS YP_004440093.1 332298171 10580056 1817959..1819233 1 NC_015500.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: nde:NIDE0254 peptidase M24; PFAM: Peptidase M24, structural domain; SPTR: Peptidase M24; IMG reference gene:2504920444; PFAM: Metallopeptidase family M24; peptidase M24 1819233 10580056 Trebr_1539 Treponema brennaborense DSM 12168 peptidase M24 YP_004440093.1 1817959 D 906968 CDS YP_004440094.1 332298172 10580057 1819217..1820221 1 NC_015500.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: tde:TDE1479 DHH superfamily protein, subfamily 1; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: DHH family protein, subfamily 1; IMG reference gene:2504920445; PFAM: DHH family; DHHA1 domain; phosphoesterase RecJ domain-containing protein 1820221 10580057 Trebr_1540 Treponema brennaborense DSM 12168 phosphoesterase RecJ domain-containing protein YP_004440094.1 1819217 D 906968 CDS YP_004440095.1 332298173 10580058 1820514..1821410 1 NC_015500.1 KEGG: tde:TDE2272 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920446; hypothetical protein 1821410 10580058 Trebr_1541 Treponema brennaborense DSM 12168 hypothetical protein YP_004440095.1 1820514 D 906968 CDS YP_004440096.1 332298174 10580059 1821423..1822100 1 NC_015500.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: Nucleoside-triphosphatase rdgB; InterPro IPR002637; KEGG: tde:TDE2271 HAM1 protein; PFAM: Ham1-like protein; PRIAM: Nucleoside-triphosphatase; SPTR: Nucleoside-triphosphatase; IMG reference gene:2504920447; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; nucleoside-triphosphatase rdgB 1822100 10580059 Trebr_1542 Treponema brennaborense DSM 12168 nucleoside-triphosphatase rdgB YP_004440096.1 1821423 D 906968 CDS YP_004440097.1 332298175 10580060 complement(1822200..1822982) 1 NC_015500.1 InterPro IPR013217; KEGG: has:Halsa_0354 methyltransferase type 12; PFAM: Methyltransferase type 12; SPTR: Methyltransferase type 12; IMG reference gene:2504920448; PFAM: Methyltransferase domain; type 12 methyltransferase 1822982 10580060 Trebr_1543 Treponema brennaborense DSM 12168 type 12 methyltransferase YP_004440097.1 1822200 R 906968 CDS YP_004440098.1 332298176 10580061 1823180..1824040 1 NC_015500.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: tde:TDE1477 flagellar filament core protein; PFAM: Flagellin, N-terminal; Flagellin, C-terminal; SPTR: Flagellar filament 31.3 kDa core protein; IMG reference gene:2504920449; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein 1824040 10580061 Trebr_1544 Treponema brennaborense DSM 12168 flagellin domain-containing protein YP_004440098.1 1823180 D 906968 CDS YP_004440099.1 332298177 10580062 1824387..1825244 1 NC_015500.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: ssm:Spirs_2598 flagellin domain protein; PFAM: Flagellin, N-terminal; Flagellin, C-terminal; SPTR: Flagellar filament 30.7 kDa core protein; IMG reference gene:2504920450; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein 1825244 10580062 Trebr_1545 Treponema brennaborense DSM 12168 flagellin domain-containing protein YP_004440099.1 1824387 D 906968 CDS YP_004440100.1 332298178 10580063 1825356..1825730 1 NC_015500.1 InterPro IPR005186; KEGG: tde:TDE1473 flagellin FlaG, PFAM: Flagellar protein FlaG protein; SPTR: Flagellin FlaG, ; IMG reference gene:2504920451; PFAM: FlaG protein; flagellar protein FlaG protein 1825730 10580063 Trebr_1546 Treponema brennaborense DSM 12168 flagellar protein FlaG protein YP_004440100.1 1825356 D 906968 CDS YP_004440101.1 332298179 10580064 1825757..1827826 1 NC_015500.1 COGs: COG1345 Flagellar capping protein; InterPro IPR003481:IPR010809; KEGG: sta:STHERM_c07710 flagellar hook-associated protein 2; PFAM: Flagellar hook-associated 2, C-terminal; Flagellar hook-associated protein 2, N-terminal; SPTR: Flagellar hook-associated protein 2; IMG reference gene:2504920452; PFAM: Flagellar hook-associated protein 2 C-terminus; flagellar hook-associated 2 domain-containing protein 1827826 10580064 Trebr_1547 Treponema brennaborense DSM 12168 flagellar hook-associated 2 domain-containing protein YP_004440101.1 1825757 D 906968 CDS YP_004440102.1 332298180 10580065 1827840..1828433 1 NC_015500.1 KEGG: tpp:TPASS_0873 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920453; hypothetical protein 1828433 10580065 Trebr_1548 Treponema brennaborense DSM 12168 hypothetical protein YP_004440102.1 1827840 D 906968 CDS YP_004440103.1 332298181 10580066 1828490..1828756 1 NC_015500.1 KEGG: bhr:BH0187 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920454; hypothetical protein 1828756 10580066 Trebr_1549 Treponema brennaborense DSM 12168 hypothetical protein YP_004440103.1 1828490 D 906968 CDS YP_004440104.1 332298182 10580067 1828753..1829187 1 NC_015500.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: tde:TDE1469 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; IMG reference gene:2504920455; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; hypothetical protein 1829187 10580067 Trebr_1550 Treponema brennaborense DSM 12168 hypothetical protein YP_004440104.1 1828753 D 906968 CDS YP_004440105.1 332298183 10580068 1829184..1829867 1 NC_015500.1 COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR000905; KEGG: sta:STHERM_c07660 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Glycoprotease family protein; TIGRFAM: universal protein YeaZ; IMG reference gene:2504920456; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; hypothetical protein 1829867 10580068 Trebr_1551 Treponema brennaborense DSM 12168 hypothetical protein YP_004440105.1 1829184 D 906968 CDS YP_004440106.1 332298184 10580069 complement(1830019..1832595) 1 NC_015500.1 InterPro IPR012970:IPR003159; KEGG: bse:Bsel_0843 hyaluronate lyase; PFAM: Polysaccharide lyase family 8, central domain; Polysaccharide lyase 8, N-terminal alpha-helical; PRIAM: Hyaluronate lyase; SPTR: Polysaccharide lyase, family 8; IMG reference gene:2504920457; PFAM: Polysaccharide lyase family 8, N terminal alpha-helical domain; Polysaccharide lyase family 8, super-sandwich domain; hyaluronate lyase 1832595 10580069 Trebr_1552 Treponema brennaborense DSM 12168 hyaluronate lyase YP_004440106.1 1830019 R 906968 CDS YP_004440107.1 332298185 10580070 complement(1832599..1834122) 1 NC_015500.1 IMG reference gene:2504920458; hypothetical protein 1834122 10580070 Trebr_1553 Treponema brennaborense DSM 12168 hypothetical protein YP_004440107.1 1832599 R 906968 CDS YP_004440108.1 332298186 10580071 complement(1834119..1837778) 1 NC_015500.1 InterProIPR003305:IPR003343:IPR012970:IPR003159:IPR 004103; KEGG: pjd:Pjdr2_3195 hyaluronate lyase; PFAM: Polysaccharide lyase 8, N-terminal alpha-helical; Bacterial Ig-like, group 2; Carbohydrate-binding, CenC-like; Polysaccharide lyase family 8, central domain; Polysaccharide lyase family 8, C-terminal; PRIAM: Hyaluronate lyase; SMART: Bacterial Ig-like, group 2; SPTR: Polysaccharide lyase family 8, super-sandwich domain protein; IMG reference gene:2504920459; PFAM: Bacterial Ig-like domain (group 2); Polysaccharide lyase family 8, N terminal alpha-helical domain; Polysaccharide lyase family 8, super-sandwich domain; Polysaccharide lyase family 8, C-terminal beta-sandwich domain; hyaluronate lyase 1837778 10580071 Trebr_1554 Treponema brennaborense DSM 12168 hyaluronate lyase YP_004440108.1 1834119 R 906968 CDS YP_004440109.1 332298187 10580072 complement(1837796..1838560) 1 NC_015500.1 IMG reference gene:2504920460; hypothetical protein 1838560 10580072 Trebr_1555 Treponema brennaborense DSM 12168 hypothetical protein YP_004440109.1 1837796 R 906968 CDS YP_004440110.1 332298188 10580073 complement(1838699..1840558) 1 NC_015500.1 InterPro IPR012970:IPR003159; KEGG: smf:Smon_0117 hyaluronate lyase; PFAM: Polysaccharide lyase 8, N-terminal alpha-helical; Polysaccharide lyase family 8, central domain; PRIAM: Hyaluronate lyase; SPTR: Hyaluronate lyase; IMG reference gene:2504920461; PFAM: Polysaccharide lyase family 8, N terminal alpha-helical domain; Polysaccharide lyase family 8, super-sandwich domain; hyaluronate lyase 1840558 10580073 Trebr_1556 Treponema brennaborense DSM 12168 hyaluronate lyase YP_004440110.1 1838699 R 906968 CDS YP_004440111.1 332298189 10580074 complement(1840614..1842167) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: smf:Smon_0123 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504920462; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 1842167 10580074 Trebr_1557 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440111.1 1840614 R 906968 CDS YP_004440112.1 332298190 10580075 complement(1842198..1843076) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: smf:Smon_0122 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Protein LplC; IMG reference gene:2504920463; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1843076 10580075 Trebr_1558 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440112.1 1842198 R 906968 CDS YP_004440113.1 332298191 10580076 complement(1843121..1844032) 1 NC_015500.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: smf:Smon_0121 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Protein LplB; IMG reference gene:2504920464; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1844032 10580076 Trebr_1559 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440113.1 1843121 R 906968 CDS YP_004440114.1 332298192 10580077 complement(1844159..1845004) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR013096:IPR000005:IPR018060; KEGG: gym:GYMC10_4654 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family protein; IMG reference gene:2504920465; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1845004 10580077 Trebr_1560 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004440114.1 1844159 R 906968 CDS YP_004440115.1 332298193 10580078 1845166..1846554 1 NC_015500.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: tma:TM0428 oxidoreductase, PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; SPTR: Oxidoreductase, ; IMG reference gene:2504920466; PFAM: NADH:flavin oxidoreductase / NADH oxidase family; NADH:flavin oxidoreductase 1846554 10580078 Trebr_1561 Treponema brennaborense DSM 12168 NADH:flavin oxidoreductase YP_004440115.1 1845166 D 906968 CDS YP_004440116.1 332298194 10580079 1846559..1847356 1 NC_015500.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: dfe:Dfer_4758 3-ketoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: uncharacterized protein; IMG reference gene:2504920467; PFAM: short chain dehydrogenase; 3-oxoacyl-ACP reductase 1847356 10580079 Trebr_1562 Treponema brennaborense DSM 12168 3-oxoacyl-ACP reductase YP_004440116.1 1846559 D 906968 CDS YP_004440117.1 332298195 10580080 1847382..1849340 1 NC_015500.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: trq:TRQ2_0517 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: uncharacterized protein; IMG reference gene:2504920468; PFAM: FAD binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 1849340 10580080 Trebr_1563 Treponema brennaborense DSM 12168 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein YP_004440117.1 1847382 D 906968 CDS YP_004440118.1 332298196 10580081 1849352..1850338 1 NC_015500.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140; KEGG: aau:AAur_3944 2-hydroxyacid family dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; IMG reference gene:2504920469; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein 1850338 10580081 Trebr_1564 Treponema brennaborense DSM 12168 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein YP_004440118.1 1849352 D 906968 CDS YP_004440119.1 332298197 10580082 1850398..1851180 1 NC_015500.1 InterPro IPR012307; KEGG: aau:AAur_3698 AP endonuclease family 2 protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: uncharacterized protein; IMG reference gene:2504920470; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase domain-containing protein TIM barrel 1851180 10580082 Trebr_1565 Treponema brennaborense DSM 12168 xylose isomerase domain-containing protein TIM barrel YP_004440119.1 1850398 D 906968 CDS YP_004440120.1 332298198 10580083 1851204..1853387 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005:IPR018060; KEGG: chd:Calhy_0723 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504920471; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1853387 10580083 Trebr_1566 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004440120.1 1851204 D 906968 CDS YP_004440121.1 332298199 10580084 complement(1853394..1855262) 1 NC_015500.1 KEGG: tpp:TPASS_0369 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920472; hypothetical protein 1855262 10580084 Trebr_1567 Treponema brennaborense DSM 12168 hypothetical protein YP_004440121.1 1853394 R 906968 CDS YP_004440122.1 332298200 10580085 complement(1855259..1855600) 1 NC_015500.1 IMG reference gene:2504920473; hypothetical protein 1855600 10580085 Trebr_1568 Treponema brennaborense DSM 12168 hypothetical protein YP_004440122.1 1855259 R 906968 CDS YP_004440123.1 332298201 10580086 complement(1855587..1858520) 1 NC_015500.1 COGs: COG1196 Chromosome segregation ATPase; InterPro IPR003395:IPR011890; KEGG: tde:TDE1496 chromosome partition protein SmC, PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: Chromosome segregation protein SMC; TIGRFAM: Chromosome segregation protein SMC; IMG reference gene:2504920474; PFAM: RecF/RecN/SMC N terminal domain; chromosome segregation protein SMC 1858520 10580086 Trebr_1569 Treponema brennaborense DSM 12168 chromosome segregation protein SMC YP_004440123.1 1855587 R 906968 CDS YP_004440124.1 332298202 10580087 complement(1858671..1859828) 1 NC_015500.1 KEGG: ssm:Spirs_1520 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920475; hypothetical protein 1859828 10580087 Trebr_1570 Treponema brennaborense DSM 12168 hypothetical protein YP_004440124.1 1858671 R 906968 CDS YP_004440125.1 332298203 10580088 complement(1859848..1860621) 1 NC_015500.1 IMG reference gene:2504920476; hypothetical protein 1860621 10580088 Trebr_1571 Treponema brennaborense DSM 12168 hypothetical protein YP_004440125.1 1859848 R 906968 CDS YP_004440126.1 332298204 10580089 complement(1860766..1861653) 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: fsu:Fisuc_1883 transcriptional regulator, LysR family; PFAM: HTH transcriptional regulator, LysR; LysR, substrate-binding; SPTR: Transcriptional regulator; IMG reference gene:2504920477; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; LysR family transcriptional regulator 1861653 10580089 Trebr_1572 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004440126.1 1860766 R 906968 CDS YP_004440127.1 332298205 10580090 1861854..1862183 1 NC_015500.1 KEGG: ele:Elen_0955 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920478; hypothetical protein 1862183 10580090 Trebr_1573 Treponema brennaborense DSM 12168 hypothetical protein YP_004440127.1 1861854 D 906968 CDS YP_004440128.1 332298206 10580091 1862159..1862713 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504920479; hypothetical protein 1862713 10580091 Trebr_1574 Treponema brennaborense DSM 12168 hypothetical protein YP_004440128.1 1862159 D 906968 CDS YP_004440129.1 332298207 10580092 1862740..1863099 1 NC_015500.1 COGs: COG3304 membrane protein; InterPro IPR005185; KEGG: efa:EF3176 hypothetical protein; PFAM: Protein of unknown function DUF307; SPTR: uncharacterized protein; IMG reference gene:2504920480; PFAM: Domain of unknown function (DUF307); hypothetical protein 1863099 10580092 Trebr_1575 Treponema brennaborense DSM 12168 hypothetical protein YP_004440129.1 1862740 D 906968 CDS YP_004440130.1 332298208 10580095 1863582..1864931 1 NC_015500.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); HAMAP: Trigger factor; InterPro IPR008881:IPR001179:IPR008880:IPR005215; KEGG: tde:TDE1671 trigger factor; PFAM: Trigger factor, C-terminal, bacterial; Trigger factor, ribosome-binding, bacterial; Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Trigger factor; TIGRFAM: Trigger factor; IMG reference gene:2504920483; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF) C-terminus; Bacterial trigger factor protein (TF); TIGRFAM: trigger factor; trigger factor Tig 1864931 10580095 Trebr_1576 Treponema brennaborense DSM 12168 trigger factor Tig YP_004440130.1 1863582 D 906968 CDS YP_004440131.1 332298209 10580096 1864968..1865582 1 NC_015500.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; HAMAP: ATP-dependent Clp protease proteolytic subunit; InterPro IPR001907; KEGG: tde:TDE1672 ATP-dependent Clp protease proteolytic subunit; PFAM: Peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit 1; IMG reference gene:2504920484; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; ATP-dependent Clp protease proteolytic subunit 1865582 10580096 Trebr_1577 Treponema brennaborense DSM 12168 ATP-dependent Clp protease proteolytic subunit YP_004440131.1 1864968 D 906968 CDS YP_004440132.1 332298210 10580097 1865566..1866813 1 NC_015500.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; HAMAP: Clp protease, ATP-binding subunit ClpX; InterProIPR010603:IPR013093:IPR019489:IPR004487:IPR 003593; KEGG: ssm:Spirs_1294 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase associated with various cellular activities, AAA-2; Zinc finger, C4-type; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX; IMG reference gene:2504920485; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); ATP-dependent Clp protease ATP-binding subunit clpX 1866813 10580097 Trebr_1578 Treponema brennaborense DSM 12168 ATP-dependent Clp protease ATP-binding subunit clpX YP_004440132.1 1865566 D 906968 CDS YP_004440133.1 332298211 10580098 complement(1866863..1867978) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: tde:TDE1544 mannosyltransferase, PFAM: Glycosyl transferase, group 1; SPTR: Mannosyltransferase, ; IMG reference gene:2504920486; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 1867978 10580098 Trebr_1579 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440133.1 1866863 R 906968 CDS YP_004440134.1 332298212 10580099 1868026..1869192 1 NC_015500.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: cbb:CLD_2860 DEAD-box ATP dependent DNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent rRNA helicase RRP3; IMG reference gene:2504920487; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase domain protein 1869192 10580099 Trebr_1580 Treponema brennaborense DSM 12168 DEAD/DEAH box helicase domain protein YP_004440134.1 1868026 D 906968 CDS YP_004440135.1 332298213 10580100 complement(1869195..1869980) 1 NC_015500.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: tde:TDE0972 ComF-related protein; PFAM: Phosphoribosyltransferase; SPTR: ComF-related protein; IMG reference gene:2504920488; phosphoribosyltransferase 1869980 10580100 Trebr_1581 Treponema brennaborense DSM 12168 phosphoribosyltransferase YP_004440135.1 1869195 R 906968 CDS YP_004440136.1 332298214 10580101 complement(1870041..1872674) 1 NC_015500.1 COGs: COG0249 Mismatch repair ATPase (MutS family); HAMAP: DNA mismatch repair protein MutS, type 1; InterProIPR007695:IPR007860:IPR007696:IPR007861:IPR 000432:IPR005748; KEGG: tde:TDE2603 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, clamp; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS, type 1; IMG reference gene:2504920489; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS; DNA mismatch repair protein mutS 1872674 10580101 Trebr_1582 Treponema brennaborense DSM 12168 DNA mismatch repair protein mutS YP_004440136.1 1870041 R 906968 CDS YP_004440137.1 332298215 10580102 complement(1872683..1873204) 1 NC_015500.1 COGs: COG2825 Outer membrane protein; InterPro IPR005632; KEGG: tpp:TPASS_0327 cationic outer membrane protein; PFAM: Outer membrane chaperone Skp (OmpH); SPTR: Cationic outer membrane protein; IMG reference gene:2504920490; PFAM: Outer membrane protein (OmpH-like); outer membrane chaperone Skp 1873204 10580102 Trebr_1583 Treponema brennaborense DSM 12168 outer membrane chaperone Skp YP_004440137.1 1872683 R 906968 CDS YP_004440138.1 332298216 10580103 complement(1873216..1875642) 1 NC_015500.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: tde:TDE2601 surface antigen, PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Outer membrane protein 88; TIGRFAM: Outer membrane assembly protein, YaeT; IMG reference gene:2504920491; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein; outer membrane protein assembly complex, YaeT protein 1875642 10580103 Trebr_1584 Treponema brennaborense DSM 12168 outer membrane protein assembly complex, YaeT protein YP_004440138.1 1873216 R 906968 CDS YP_004440139.1 332298217 10580104 complement(1875655..1880124) 1 NC_015500.1 InterPro IPR007452; KEGG: tde:TDE2600 hypothetical protein; PFAM: Protein of unknown function DUF490; SPTR: uncharacterized protein; IMG reference gene:2504920492; PFAM: Family of unknown function (DUF490); hypothetical protein 1880124 10580104 Trebr_1585 Treponema brennaborense DSM 12168 hypothetical protein YP_004440139.1 1875655 R 906968 CDS YP_004440140.1 332298218 10580105 1880176..1880802 1 NC_015500.1 COGs: COG0125 Thymidylate kinase; HAMAP: Thymidylate kinase; InterPro IPR000062:IPR018094; KEGG: tde:TDE2599 thymidylate kinase; PFAM: Thymidylate kinase-like; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: Thymidylate kinase; IMG reference gene:2504920493; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase; thymidylate kinase 1880802 10580105 Trebr_1586 Treponema brennaborense DSM 12168 thymidylate kinase YP_004440140.1 1880176 D 906968 CDS YP_004440141.1 332298219 10580106 1880799..1881479 1 NC_015500.1 KEGG: tde:TDE2598 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920494; hypothetical protein 1881479 10580106 Trebr_1587 Treponema brennaborense DSM 12168 hypothetical protein YP_004440141.1 1880799 D 906968 CDS YP_004440142.1 332298220 10580107 1881489..1882649 1 NC_015500.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: sta:STHERM_c15820 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; IMG reference gene:2504920495; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; 3-dehydroquinate synthase 1882649 10580107 Trebr_1588 Treponema brennaborense DSM 12168 3-dehydroquinate synthase YP_004440142.1 1881489 D 906968 CDS YP_004440143.1 332298221 10580108 1882665..1883891 1 NC_015500.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: tde:TDE0103 aminotransferase, class-V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; IMG reference gene:2504920496; PFAM: Aminotransferase class-V; Cysteine desulfurase 1883891 10580108 Trebr_1589 Treponema brennaborense DSM 12168 Cysteine desulfurase YP_004440143.1 1882665 D 906968 CDS YP_004440144.1 332298222 10580109 complement(1883983..1885572) 1 NC_015500.1 COGs: COG1543 conserved hypothetical protein; InterPro IPR004300:IPR015293; KEGG: ssm:Spirs_1542 domain of unknown function DUF1957; PFAM: Domain of unknown function DUF1957; Glycoside hydrolase, family 57, core; SPTR: Glycosyl hydrolase, family 57; IMG reference gene:2504920497; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; hypothetical protein 1885572 10580109 Trebr_1590 Treponema brennaborense DSM 12168 hypothetical protein YP_004440144.1 1883983 R 906968 CDS YP_004440145.1 332298223 10580110 complement(1885587..1886252) 1 NC_015500.1 KEGG: tde:TDE1093 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920498; hypothetical protein 1886252 10580110 Trebr_1591 Treponema brennaborense DSM 12168 hypothetical protein YP_004440145.1 1885587 R 906968 CDS YP_004440146.1 332298224 10580111 1886521..1888293 1 NC_015500.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: tde:TDE1998 phosphohexose mutase family protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Phosphoglucomutase; IMG reference gene:2504920499; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 1888293 10580111 Trebr_1592 Treponema brennaborense DSM 12168 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_004440146.1 1886521 D 906968 CDS YP_004440147.1 332298225 10580112 1888280..1888840 1 NC_015500.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR013520:IPR006055:IPR006054; KEGG: tde:TDE1999 DNA polymerase III domain-containing protein; PFAM: Exonuclease, RNase T/DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: DNA polymerase III domain protein; TIGRFAM: DNA polymerase III, epsilon subunit; IMG reference gene:2504920500; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DNA polymerase III subunit epsilon 1888840 10580112 Trebr_1593 Treponema brennaborense DSM 12168 DNA polymerase III subunit epsilon YP_004440147.1 1888280 D 906968 CDS YP_004440148.1 332298226 10580113 complement(1888858..1889856) 1 NC_015500.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR009042:IPR007627:IPR007624:IPR007630:IPR 014284; KEGG: sta:STHERM_c10120 RNA polymerase sigma factor RpoD; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504920501; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 1889856 10580113 Trebr_1594 Treponema brennaborense DSM 12168 RpoD subfamily RNA polymerase sigma-70 subunit YP_004440148.1 1888858 R 906968 CDS YP_004440149.1 332298227 10580114 complement(1889975..1890829) 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: tde:TDE1297 LysM/M23/M37 peptidase; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: LysM domain/M23/M37 peptidase domain protein; IMG reference gene:2504920502; PFAM: Peptidase family M23; LysM domain; peptidase M23 1890829 10580114 Trebr_1595 Treponema brennaborense DSM 12168 peptidase M23 YP_004440149.1 1889975 R 906968 CDS YP_004440150.1 332298228 10580115 complement(1890864..1892132) 1 NC_015500.1 COGs: COG1896 hydrolase of HD superfamily; KEGG: tde:TDE1299 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920503; hypothetical protein 1892132 10580115 Trebr_1596 Treponema brennaborense DSM 12168 hypothetical protein YP_004440150.1 1890864 R 906968 CDS YP_004440151.1 332298229 10580116 complement(1892152..1892985) 1 NC_015500.1 COGs: COG1338 Flagellar biosynthesis pathway component FliP; InterPro IPR005838:IPR005837; KEGG: tde:TDE2760 flagellar biosynthesis protein FliP; PFAM: Type III secretion system inner membrane P protein; SPTR: Flagellar biosynthetic protein FliP; TIGRFAM: Flagellar transport protein FliP; IMG reference gene:2504920504; PFAM: FliP family; TIGRFAM: flagellar biosynthetic protein FliP; flagellar biosynthetic protein FliP 1892985 10580116 Trebr_1597 Treponema brennaborense DSM 12168 flagellar biosynthetic protein FliP YP_004440151.1 1892152 R 906968 CDS YP_004440152.1 332298230 10580117 complement(1892982..1893704) 1 NC_015500.1 KEGG: tde:TDE2761 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920505; PFAM: Flagellar biosynthesis protein, FliO; hypothetical protein 1893704 10580117 Trebr_1598 Treponema brennaborense DSM 12168 hypothetical protein YP_004440152.1 1892982 R 906968 CDS YP_004440153.1 332298231 10580118 complement(1893765..1894955) 1 NC_015500.1 COGs: COG1886 Flagellar motor switch/type III secretory pathway protein; InterPro IPR001543:IPR012826; KEGG: tde:TDE2762 flagellar motor switch protein FliY; PFAM: Surface presentation of antigen (SpoA); SPTR: Flagellar motor switch protein FliY; TIGRFAM: Flagellar motor switch FliN; IMG reference gene:2504920506; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN; flagellar motor switch protein FliN 1894955 10580118 Trebr_1599 Treponema brennaborense DSM 12168 flagellar motor switch protein FliN YP_004440153.1 1893765 R 906968 CDS YP_004440154.1 332298232 10580119 complement(1894948..1895982) 1 NC_015500.1 COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: tpp:TPASS_0721 flagellar motor switch protein FliM; PFAM: Flagellar motor switch protein FliM; Surface presentation of antigen (SpoA); SPTR: Flagellar motor switch protein FliM; TIGRFAM: Flagellar motor switch protein FliM; IMG reference gene:2504920507; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; flagellar motor switch protein FliM 1895982 10580119 Trebr_1600 Treponema brennaborense DSM 12168 flagellar motor switch protein FliM YP_004440154.1 1894948 R 906968 CDS YP_004440155.1 332298233 10580120 complement(1896119..1896664) 1 NC_015500.1 COGs: COG1580 Flagellar basal body-associated protein; InterPro IPR005503; KEGG: tde:TDE2764 flagellar basal body-associated protein FliL; PFAM: Flagellar basal body-associated protein FliL; SPTR: Flagellar protein FliL; IMG reference gene:2504920508; PFAM: Flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 1896664 10580120 Trebr_1601 Treponema brennaborense DSM 12168 flagellar basal body-associated protein FliL YP_004440155.1 1896119 R 906968 CDS YP_004440156.1 332298234 10580121 complement(1896697..1897407) 1 NC_015500.1 COGs: COG1360 Flagellar motor protein; InterPro IPR006665; KEGG: tde:TDE2765 flagellar motor protein MotB; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: Chemotaxis protein MotB; IMG reference gene:2504920509; PFAM: OmpA family; OmpA/MotB domain-containing protein 1897407 10580121 Trebr_1602 Treponema brennaborense DSM 12168 OmpA/MotB domain-containing protein YP_004440156.1 1896697 R 906968 CDS YP_004440157.1 332298235 10580122 complement(1897420..1898202) 1 NC_015500.1 COGs: COG1291 Flagellar motor component; InterPro IPR002898; KEGG: tde:TDE2766 motility protein A; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Motility protein A; IMG reference gene:2504920510; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel 1898202 10580122 Trebr_1603 Treponema brennaborense DSM 12168 MotA/TolQ/ExbB proton channel YP_004440157.1 1897420 R 906968 CDS YP_004440158.1 332298236 10580123 complement(1898223..1898420) 1 NC_015500.1 COGs: COG1582 Uncharacterized protein possibly involved in motility; InterPro IPR009384; KEGG: tde:TDE2767 flagellar protein-related protein; PFAM: Flagellar; SPTR: Flagellar protein-related protein; IMG reference gene:2504920511; PFAM: Flagellar protein (FlbD); flagellar FlbD family protein 1898420 10580123 Trebr_1604 Treponema brennaborense DSM 12168 flagellar FlbD family protein YP_004440158.1 1898223 R 906968 CDS YP_004440159.1 332298237 10580124 complement(1898773..1900164) 1 NC_015500.1 COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR001444:IPR011491:IPR010930:IPR020013; KEGG: tde:TDE2768 flagellar hook protein FlgE; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook protein FlgE; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504920512; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; Flagellar basal body protein FlaE; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; flagellar hook-basal body protein 1900164 10580124 Trebr_1605 Treponema brennaborense DSM 12168 flagellar hook-basal body protein YP_004440159.1 1898773 R 906968 CDS YP_004440160.1 332298238 10580125 complement(1900177..1900617) 1 NC_015500.1 COGs: COG1843 Flagellar hook capping protein; InterPro IPR005648; KEGG: ssm:Spirs_1569 flagellar hook capping protein; PFAM: Flagellar hook capping protein; SPTR: Flagellar hook capping protein; IMG reference gene:2504920513; PFAM: Flagellar hook capping protein; flagellar hook capping protein 1900617 10580125 Trebr_1606 Treponema brennaborense DSM 12168 flagellar hook capping protein YP_004440160.1 1900177 R 906968 CDS YP_004440161.1 332298239 10580126 complement(1900686..1902029) 1 NC_015500.1 InterPro IPR001635; KEGG: tde:TDE2770 flagellar hook-length control protein FliK; PFAM: Flagellar hook-length control protein; SPTR: Flagellar hook-length control protein FliK; IMG reference gene:2504920514; PFAM: Flagellar hook-length control protein FliK; flagellar hook-length control protein 1902029 10580126 Trebr_1607 Treponema brennaborense DSM 12168 flagellar hook-length control protein YP_004440161.1 1900686 R 906968 CDS YP_004440162.1 332298240 10580127 1902184..1902834 1 NC_015500.1 COGs: COG2344 AT-rich DNA-binding protein; HAMAP: Redox-sensing transcriptional repressor rex; InterPro IPR003781; KEGG: tde:TDE1912 redox-sensing transcriptional repressor REX; PFAM: CoA-binding; SPTR: Redox-sensing transcriptional repressor rex; IMG reference gene:2504920515; PFAM: CoA binding domain; DNA-binding protein N-terminus; redox-sensing transcriptional repressor rex 1902834 10580127 Trebr_1608 Treponema brennaborense DSM 12168 redox-sensing transcriptional repressor rex YP_004440162.1 1902184 D 906968 CDS YP_004440163.1 332298241 10580128 1902837..1903916 1 NC_015500.1 COGs: COG1092 SAM-dependent methyltransferase; KEGG: tde:TDE1913 hypothetical protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504920516; PFAM: S-adenosylmethionine-dependent methyltransferase; rRNA (guanine-N(2)-)-methyltransferase 1903916 10580128 Trebr_1609 Treponema brennaborense DSM 12168 rRNA (guanine-N(2)-)-methyltransferase YP_004440163.1 1902837 D 906968 CDS YP_004440164.1 332298242 10580129 1903965..1904996 1 NC_015500.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: cst:CLOST_1414 beta-lactamase-like; SPTR: Beta-lactamase domain-containing protein; IMG reference gene:2504920517; PFAM: Metallo-beta-lactamase superfamily; beta-lactamase 1904996 10580129 Trebr_1610 Treponema brennaborense DSM 12168 beta-lactamase YP_004440164.1 1903965 D 906968 CDS YP_004440165.1 332298243 10580130 1905196..1905591 1 NC_015500.1 InterPro IPR006628; KEGG: tde:TDE0865 hypothetical protein; SMART: PUR-alpha/beta/gamma, DNA/RNA-binding; SPTR: uncharacterized protein; IMG reference gene:2504920518; PFAM: Protein of unknown function (DUF3276); PurA ssDNA and RNA-binding protein; PUR-alpha/beta/gamma DNA/RNA-binding protein 1905591 10580130 Trebr_1611 Treponema brennaborense DSM 12168 PUR-alpha/beta/gamma DNA/RNA-binding protein YP_004440165.1 1905196 D 906968 CDS YP_004440166.1 332298244 10580131 complement(1905817..1906410) 1 NC_015500.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: tde:TDE1547 ribonuclease HII; PFAM: Ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease HII; IMG reference gene:2504920519; PFAM: Ribonuclease HII; Ribonuclease H 1906410 10580131 Trebr_1612 Treponema brennaborense DSM 12168 Ribonuclease H YP_004440166.1 1905817 R 906968 CDS YP_004440167.1 332298245 10580132 complement(1906410..1907693) 1 NC_015500.1 KEGG: rsp:RSP_6158 light-harvesting complex alpha subunit; SPTR: Ice-structuring glycoprotein; IMG reference gene:2504920520; hypothetical protein 1907693 10580132 Trebr_1613 Treponema brennaborense DSM 12168 hypothetical protein YP_004440167.1 1906410 R 906968 CDS YP_004440168.1 332298246 10580133 complement(1907695..1908735) 1 NC_015500.1 KEGG: tcr:506269.40 mucin-associated surface protein (MASP); SPTR: Mucin-associated surface protein (MASP), ; IMG reference gene:2504920521; hypothetical protein 1908735 10580133 Trebr_1614 Treponema brennaborense DSM 12168 hypothetical protein YP_004440168.1 1907695 R 906968 CDS YP_004440169.1 332298247 10580134 complement(1908732..1910966) 1 NC_015500.1 KEGG: tde:TDE1546 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920522; hypothetical protein 1910966 10580134 Trebr_1615 Treponema brennaborense DSM 12168 hypothetical protein YP_004440169.1 1908732 R 906968 CDS YP_004440170.1 332298248 10580135 complement(1910982..1911584) 1 NC_015500.1 COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: ssm:Spirs_2435 phosphoribosyl transferase domain protein; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyl transferase domain protein; IMG reference gene:2504920523; PFAM: Phosphoribosyl transferase domain; phosphoribosyltransferase 1911584 10580135 Trebr_1616 Treponema brennaborense DSM 12168 phosphoribosyltransferase YP_004440170.1 1910982 R 906968 CDS YP_004440171.1 332298249 10580136 1911714..1912172 1 NC_015500.1 IMG reference gene:2504920524; hypothetical protein 1912172 10580136 Trebr_1617 Treponema brennaborense DSM 12168 hypothetical protein YP_004440171.1 1911714 D 906968 CDS YP_004440172.1 332298250 10580137 complement(1912255..1912935) 1 NC_015500.1 KEGG: dtu:Dtur_0045 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920525; hypothetical protein 1912935 10580137 Trebr_1618 Treponema brennaborense DSM 12168 hypothetical protein YP_004440172.1 1912255 R 906968 CDS YP_004440173.1 332298251 10580138 complement(1912951..1914393) 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: clj:CLJU_c30640 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: His Kinase A domain protein; IMG reference gene:2504920526; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 1914393 10580138 Trebr_1619 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004440173.1 1912951 R 906968 CDS YP_004440174.1 332298252 10580139 complement(1914390..1915124) 1 NC_015500.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: swo:Swol_2177 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver domain protein; IMG reference gene:2504920527; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; two component transcriptional regulator, winged helix family 1915124 10580139 Trebr_1620 Treponema brennaborense DSM 12168 two component transcriptional regulator, winged helix family YP_004440174.1 1914390 R 906968 CDS YP_004440175.1 332298253 10580140 complement(1915173..1916015) 1 NC_015500.1 COGs: COG3717 5-keto 4-deoxyuronate isomerase; HAMAP: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; InterPro IPR007045; KEGG: csh:Closa_3486 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; PFAM: 5-keto 4-deoxyuronate isomerase; PRIAM: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; SPTR: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; IMG reference gene:2504920528; PFAM: KduI/IolB family; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 1916015 10580140 Trebr_1621 Treponema brennaborense DSM 12168 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase YP_004440175.1 1915173 R 906968 CDS YP_004440176.1 332298254 10580141 1916265..1917779 1 NC_015500.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890; KEGG: fsu:Fisuc_0137 anthranilate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase; IMG reference gene:2504920529; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; anthranilate synthase 1917779 10580141 Trebr_1622 Treponema brennaborense DSM 12168 anthranilate synthase YP_004440176.1 1916265 D 906968 CDS YP_004440177.1 332298255 10580142 1917964..1919571 1 NC_015500.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; HAMAP: Anthranilate phosphoribosyl transferase; InterProIPR000991:IPR017459:IPR000312:IPR005940:IPR 006221; KEGG: fsu:Fisuc_0138 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase, family 3; Glutamine amidotransferase class-I, C-terminal; Glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate synthase., Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase; Glutamine amidotransferase of anthranilate synthase; IMG reference gene:2504920530; PFAM: Glutamine amidotransferase class-I; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; anthranilate phosphoribosyltransferase; anthranilate phosphoribosyltransferase 1919571 10580142 Trebr_1623 Treponema brennaborense DSM 12168 anthranilate phosphoribosyltransferase YP_004440177.1 1917964 D 906968 CDS YP_004440178.1 332298256 10580143 1919564..1921156 1 NC_015500.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240; KEGG: fsu:Fisuc_0176 indole-3-glycerol-phosphate synthase., phosphoribosylanthranilate isomerase; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; IMG reference gene:2504920531; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase 1921156 10580143 Trebr_1624 Treponema brennaborense DSM 12168 Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase YP_004440178.1 1919564 D 906968 CDS YP_004440179.1 332298257 10580144 1921175..1922581 1 NC_015500.1 COGs: COG0133 Tryptophan synthase beta chain; HAMAP: Tryptophan synthase beta chain; InterPro IPR001926:IPR006654; KEGG: fsu:Fisuc_0179 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain; TIGRFAM: Tryptophan synthase, beta chain; IMG reference gene:2504920532; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit; tryptophan synthase subunit beta 1922581 10580144 Trebr_1625 Treponema brennaborense DSM 12168 tryptophan synthase subunit beta YP_004440179.1 1921175 D 906968 CDS YP_004440180.1 332298258 10580145 1922606..1923427 1 NC_015500.1 COGs: COG0159 Tryptophan synthase alpha chain; HAMAP: Tryptophan synthase, alpha chain; InterPro IPR002028; KEGG: fsu:Fisuc_0180 tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase, alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: Tryptophan synthase, alpha chain; IMG reference gene:2504920533; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit; tryptophan synthase subunit alpha 1923427 10580145 Trebr_1626 Treponema brennaborense DSM 12168 tryptophan synthase subunit alpha YP_004440180.1 1922606 D 906968 CDS YP_004440181.1 332298259 10580146 complement(1923514..1925070) 1 NC_015500.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015882:IPR015883; KEGG: beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; Beta-N-acetylhexosaminidase-like; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; IMG reference gene:2504920534; PFAM: Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2; beta-N-acetylhexosaminidase 1925070 10580146 Trebr_1627 Treponema brennaborense DSM 12168 beta-N-acetylhexosaminidase YP_004440181.1 1923514 R 906968 CDS YP_004440182.1 332298260 10580147 1925219..1927537 1 NC_015500.1 KEGG: mat:MARTH_orf576 hypothetical lipoprotein; SPTR: Hypothetical lipoprotein; IMG reference gene:2504920535; hypothetical protein 1927537 10580147 Trebr_1628 Treponema brennaborense DSM 12168 hypothetical protein YP_004440182.1 1925219 D 906968 CDS YP_004440183.1 332298261 10580148 1927744..1929393 1 NC_015500.1 KEGG: mat:MARTH_orf722 hypothetical lipoprotein; SPTR: Hypothetical lipoprotein; IMG reference gene:2504920536; hypothetical protein 1929393 10580148 Trebr_1629 Treponema brennaborense DSM 12168 hypothetical protein YP_004440183.1 1927744 D 906968 CDS YP_004440184.1 332298262 10580149 complement(1929734..1930324) 1 NC_015500.1 COGs: COG2818 3-methyladenine DNA glycosylase; InterPro IPR005019; KEGG: ssm:Spirs_2955 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase; PRIAM: DNA-3-methyladenine glycosylase I; SPTR: uncharacterized protein; IMG reference gene:2504920537; PFAM: Methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I; DNA-3-methyladenine glycosylase I 1930324 10580149 Trebr_1630 Treponema brennaborense DSM 12168 DNA-3-methyladenine glycosylase I YP_004440184.1 1929734 R 906968 CDS YP_004440185.1 332298263 10580150 complement(1930413..1931618) 1 NC_015500.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: vvu:VV1_0811 nucleoside-diphosphate sugar epimerase; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: UDP-N-acetylglucosamine 4,6-dehydratase; IMG reference gene:2504920538; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein CapD 1931618 10580150 Trebr_1631 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein CapD YP_004440185.1 1930413 R 906968 CDS YP_004440186.1 332298264 10580151 complement(1931704..1932369) 1 NC_015500.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: pna:Pnap_3116 sugar transferase; PFAM: Bacterial sugar transferase; SPTR: Probable sugar transferase, WBGY; IMG reference gene:2504920539; PFAM: Bacterial sugar transferase; sugar transferase 1932369 10580151 Trebr_1632 Treponema brennaborense DSM 12168 sugar transferase YP_004440186.1 1931704 R 906968 CDS YP_004440187.1 332298265 10580152 complement(1932366..1932650) 1 NC_015500.1 IMG reference gene:2504920540; hypothetical protein 1932650 10580152 Trebr_1633 Treponema brennaborense DSM 12168 hypothetical protein YP_004440187.1 1932366 R 906968 CDS YP_004440188.1 332298266 10580153 complement(1932661..1933488) 1 NC_015500.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: mtp:Mthe_0965 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, family 2; IMG reference gene:2504920541; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 1933488 10580153 Trebr_1634 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440188.1 1932661 R 906968 CDS YP_004440189.1 332298267 10580154 complement(1933508..1934653) 1 NC_015500.1 KEGG: mma:MM_2099 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920542; PFAM: Acyltransferase family; hypothetical protein 1934653 10580154 Trebr_1635 Treponema brennaborense DSM 12168 hypothetical protein YP_004440189.1 1933508 R 906968 CDS YP_004440190.1 332298268 10580155 complement(1934656..1935084) 1 NC_015500.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: ipo:Ilyop_1005 ribose-5-phosphate isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Galactose-6-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: Ribose 5-phosphate isomerase B; Ribose/galactose isomerase; IMG reference gene:2504920543; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B 1935084 10580155 Trebr_1636 Treponema brennaborense DSM 12168 ribose 5-phosphate isomerase B YP_004440190.1 1934656 R 906968 CDS YP_004440191.1 332298269 10580156 complement(1935081..1935794) 1 NC_015500.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; HAMAP: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; InterPro IPR001228; KEGG: fsu:Fisuc_0980 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1; IMG reference gene:2504920544; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1935794 10580156 Trebr_1637 Treponema brennaborense DSM 12168 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004440191.1 1935081 R 906968 CDS YP_004440192.1 332298270 10580157 complement(1935796..1936857) 1 NC_015500.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: cno:NT01CX_1063 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; IMG reference gene:2504920545; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Histidinol-phosphate transaminase 1936857 10580157 Trebr_1638 Treponema brennaborense DSM 12168 Histidinol-phosphate transaminase YP_004440192.1 1935796 R 906968 CDS YP_004440193.1 332298271 10580158 complement(1936964..1938121) 1 NC_015500.1 COGs: COG1887 glycosyl/glycerophosphate transferase involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; InterPro IPR007554; KEGG: pdi:BDI_1348 glycero-phosphotransferase; PFAM: CDP-glycerol glycerophosphotransferase; SPTR: glycero-phosphotransferase; IMG reference gene:2504920546; PFAM: CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; CDP- glycerol:poly(glycerophosphate)glycerophosphotransferase 1938121 10580158 Trebr_1639 Treponema brennaborense DSM 12168 CDP- glycerol:poly(glycerophosphate)glycerophosphotransferase YP_004440193.1 1936964 R 906968 CDS YP_004440194.1 332298272 10580159 complement(1938135..1939250) 1 NC_015500.1 KEGG: ccb:Clocel_2378 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920547; hypothetical protein 1939250 10580159 Trebr_1640 Treponema brennaborense DSM 12168 hypothetical protein YP_004440194.1 1938135 R 906968 CDS YP_004440195.1 332298273 10580160 complement(1939240..1940664) 1 NC_015500.1 KEGG: str:Sterm_2396 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920548; hypothetical protein 1940664 10580160 Trebr_1641 Treponema brennaborense DSM 12168 hypothetical protein YP_004440195.1 1939240 R 906968 CDS YP_004440196.1 332298274 10580161 complement(1940661..1941815) 1 NC_015500.1 COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR003329:IPR005834:IPR010023:IPR006549; KEGG: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PFAM: Haloacid dehalogenase-like hydrolase; Acylneuraminate cytidylyltransferase; PRIAM: N-acylneuraminate cytidylyltransferase., 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: N-acylneuraminate cytidylyltransferase; TIGRFAM: Phosphatase KdsC; HAD-superfamily hydrolase, subfamily IIIA; IMG reference gene:2504920549; PFAM: Cytidylyltransferase; haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1941815 10580161 Trebr_1642 Treponema brennaborense DSM 12168 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_004440196.1 1940661 R 906968 CDS YP_004440197.1 332298275 10580162 complement(1941824..1942699) 1 NC_015500.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132; KEGG: N-acetylneuraminate synthase; PFAM: N-acetylneuraminic acid synthase, N-terminal; PRIAM: N-acetylneuraminate synthase; SPTR: N-acylneuraminate-9-phosphate synthase; IMG reference gene:2504920550; PFAM: NeuB family; N-acetylneuraminate synthase 1942699 10580162 Trebr_1643 Treponema brennaborense DSM 12168 N-acetylneuraminate synthase YP_004440197.1 1941824 R 906968 CDS YP_004440198.1 332298276 10580163 complement(1942703..1944160) 1 NC_015500.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ere:EUBREC_2630 O-antigen transporter; PFAM: Polysaccharide biosynthesis protein; SPTR: O-antigen transporter; IMG reference gene:2504920551; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 1944160 10580163 Trebr_1644 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004440198.1 1942703 R 906968 CDS YP_004440199.1 332298277 10580164 complement(1944757..1945284) 1 NC_015500.1 KEGG: ssm:Spirs_1333 NusG antitermination factor; SPTR: NusG antitermination factor; IMG reference gene:2504920552; PFAM: KOW motif; hypothetical protein 1945284 10580164 Trebr_1645 Treponema brennaborense DSM 12168 hypothetical protein YP_004440199.1 1944757 R 906968 CDS YP_004440200.1 332298278 10580165 complement(1945338..1946060) 1 NC_015500.1 IMG reference gene:2504920553; hypothetical protein 1946060 10580165 Trebr_1646 Treponema brennaborense DSM 12168 hypothetical protein YP_004440200.1 1945338 R 906968 CDS YP_004440201.1 332298279 10580166 1946175..1946501 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504920554; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 1946501 10580166 Trebr_1647 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440201.1 1946175 D 906968 CDS YP_004440202.1 332298280 10580167 1946821..1947756 1 NC_015500.1 InterPro IPR010106; KEGG: afn:Acfer_1259 tetracycline resistance leader peptide; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504920555; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 1947756 10580167 Trebr_1648 Treponema brennaborense DSM 12168 hypothetical protein YP_004440202.1 1946821 D 906968 CDS YP_004440203.1 332298281 10580169 complement(1948999..1950222) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bad:BAD_1387 spore coat protein; PFAM: Glycosyl transferase, group 1; SPTR: Spore coat protein; IMG reference gene:2504920557; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 1950222 10580169 Trebr_1650 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440203.1 1948999 R 906968 CDS YP_004440204.1 332298282 10580170 complement(1950219..1951175) 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sne:SPN23F_03260 glycosyltransferase WchA; PFAM: Glycosyl transferase, family 2; SPTR: glycosyltransferase WchA; IMG reference gene:2504920558; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 1951175 10580170 Trebr_1651 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440204.1 1950219 R 906968 CDS YP_004440205.1 332298283 10580171 complement(1951177..1952367) 1 NC_015500.1 KEGG: sec:SC2098 O-antigen polymerase; SPTR: O-antigen polymerase; IMG reference gene:2504920559; hypothetical protein 1952367 10580171 Trebr_1652 Treponema brennaborense DSM 12168 hypothetical protein YP_004440205.1 1951177 R 906968 CDS YP_004440206.1 332298284 10580172 complement(1952364..1953533) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: zpr:ZPR_0557 glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: glycosyltransferase HI1698; IMG reference gene:2504920560; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 1953533 10580172 Trebr_1653 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440206.1 1952364 R 906968 CDS YP_004440207.1 332298285 10580173 complement(1953578..1954624) 1 NC_015500.1 KEGG: bfs:BF2794 hypothetical protein; SPTR: WfaX; IMG reference gene:2504920561; PFAM: Polysaccharide pyruvyl transferase; hypothetical protein 1954624 10580173 Trebr_1654 Treponema brennaborense DSM 12168 hypothetical protein YP_004440207.1 1953578 R 906968 CDS YP_004440208.1 332298286 10580174 complement(1954803..1955006) 1 NC_015500.1 KEGG: cjd:JJD26997_0963 hypothetical protein; SPTR: RelE/StbE family addiction module toxin; manually curated; IMG reference gene:2504920562; hypothetical protein 1955006 10580174 Trebr_1655 Treponema brennaborense DSM 12168 hypothetical protein YP_004440208.1 1954803 R 906968 CDS YP_004440209.1 332298287 10580175 complement(1954978..1955190) 1 NC_015500.1 IMG reference gene:2504920563; hypothetical protein 1955190 10580175 Trebr_1656 Treponema brennaborense DSM 12168 hypothetical protein YP_004440209.1 1954978 R 906968 CDS YP_004440210.1 332298288 10580176 complement(1955236..1956471) 1 NC_015500.1 COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR001450:IPR007525; KEGG: amt:Amet_0212 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2504920564; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; coenzyme F420 hydrogenase/dehydrogenase subunit beta domain-containing protein 1956471 10580176 Trebr_1657 Treponema brennaborense DSM 12168 coenzyme F420 hydrogenase/dehydrogenase subunit beta domain-containing protein YP_004440210.1 1955236 R 906968 CDS YP_004440211.1 332298289 10580177 complement(1956461..1958011) 1 NC_015500.1 InterPro IPR002797; KEGG: dfe:Dfer_0062 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2504920565; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 1958011 10580177 Trebr_1658 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004440211.1 1956461 R 906968 CDS YP_004440212.1 332298290 10580178 complement(1958008..1958892) 1 NC_015500.1 IMG reference gene:2504920566; hypothetical protein 1958892 10580178 Trebr_1659 Treponema brennaborense DSM 12168 hypothetical protein YP_004440212.1 1958008 R 906968 CDS YP_004440213.1 332298291 10580179 1958972..1959292 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; manually curated; IMG reference gene:2504920567; PFAM: Bacteriophage CI repressor helix-turn-helix domain; helix-turn-helix domain-containing protein 1959292 10580179 Trebr_1660 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440213.1 1958972 D 906968 CDS YP_004440214.1 332298292 10580180 1959502..1960458 1 NC_015500.1 COGs: COG1162 GTPase; HAMAP: ribosome biogenesis GTPase RsgA; InterPro IPR004881; KEGG: tde:TDE1449 GTPase YjeQ; PFAM: GTPase EngC; SPTR: Ribosome small subunit-dependent GTPase A; TIGRFAM: GTPase EngC; IMG reference gene:2504920568; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A; ribosome biogenesis GTPase RsgA 1960458 10580180 Trebr_1661 Treponema brennaborense DSM 12168 ribosome biogenesis GTPase RsgA YP_004440214.1 1959502 D 906968 CDS YP_004440215.1 332298293 10580181 1960482..1963094 1 NC_015500.1 COGs: COG1193 Mismatch repair ATPase (MutS family); HAMAP: MutS2 protein; InterPro IPR000432:IPR002625:IPR007696; KEGG: tde:TDE1450 MutS2 family protein; PFAM: Smr protein/MutS2 C-terminal; DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; Smr protein/MutS2 C-terminal; SPTR: MutS2 protein; IMG reference gene:2504920569; PFAM: MutS domain V; Smr domain; MutS2 protein 1963094 10580181 Trebr_1662 Treponema brennaborense DSM 12168 MutS2 protein YP_004440215.1 1960482 D 906968 CDS YP_004440216.1 332298294 10580182 complement(1963195..1963845) 1 NC_015500.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR000551:IPR002178:IPR010093; KEGG: tde:TDE1079 DNA-binding protein/PTS system, IIA component; PFAM: HTH transcriptional regulator, MerR; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: DNA-binding protein/PTS system, IIA component; TIGRFAM: Excisionase/Xis, DNA-binding; IMG reference gene:2504920570; PFAM: Prophage CP4-57 regulatory protein (AlpA); Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: DNA binding domain, excisionase family; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 1963845 10580182 Trebr_1663 Treponema brennaborense DSM 12168 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_004440216.1 1963195 R 906968 CDS YP_004440217.1 332298295 10580183 complement(1963930..1964337) 1 NC_015500.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR006262; KEGG: tde:TDE1931 cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: Cytidine deaminase, homotetrameric; IMG reference gene:2504920571; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric; cytidine deaminase 1964337 10580183 Trebr_1664 Treponema brennaborense DSM 12168 cytidine deaminase YP_004440217.1 1963930 R 906968 CDS YP_004440218.1 332298296 10580184 1964458..1965540 1 NC_015500.1 KEGG: tpp:TPASS_0783 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920572; hypothetical protein 1965540 10580184 Trebr_1665 Treponema brennaborense DSM 12168 hypothetical protein YP_004440218.1 1964458 D 906968 CDS YP_004440219.1 332298297 10580185 1965566..1966441 1 NC_015500.1 InterPro IPR016047; KEGG: tde:TDE1929 hypothetical protein; PFAM: Peptidase M23; SPTR: M23 peptidase domain protein; IMG reference gene:2504920573; PFAM: Peptidase family M23; peptidase M23 1966441 10580185 Trebr_1666 Treponema brennaborense DSM 12168 peptidase M23 YP_004440219.1 1965566 D 906968 CDS YP_004440220.1 332298298 10580186 complement(1966558..1967154) 1 NC_015500.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR007419; KEGG: plt:Plut_0236 IscU protein; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; BFD-like [2Fe-2S]-binding region; SPTR: IscU protein; IMG reference gene:2504920574; PFAM: NifU-like N terminal domain; BFD-like [2Fe-2S] binding domain; nitrogen-fixing NifU domain-containing protein 1967154 10580186 Trebr_1667 Treponema brennaborense DSM 12168 nitrogen-fixing NifU domain-containing protein YP_004440220.1 1966558 R 906968 CDS YP_004440221.1 332298299 10580187 complement(1967178..1968344) 1 NC_015500.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: ssm:Spirs_3170 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; IMG reference gene:2504920575; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS; Cysteine desulfurase 1968344 10580187 Trebr_1668 Treponema brennaborense DSM 12168 Cysteine desulfurase YP_004440221.1 1967178 R 906968 CDS YP_004440222.1 332298300 10580188 complement(1968349..1969707) 1 NC_015500.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR018318:IPR004506; KEGG: fsu:Fisuc_1073 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase-like; SPTR: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; manually curated; IMG reference gene:2504920576; PFAM: tRNA methyl transferase; tRNA-specific 2-thiouridylase mnmA 1969707 10580188 Trebr_1669 Treponema brennaborense DSM 12168 tRNA-specific 2-thiouridylase mnmA YP_004440222.1 1968349 R 906968 CDS YP_004440223.1 332298301 10580189 complement(1969861..1970721) 1 NC_015500.1 COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: dhd:Dhaf_2653 phosphomethylpyrimidine kinase type-1; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: Phosphomethylpyrimidine kinase type-1; IMG reference gene:2504920577; PFAM: Phosphomethylpyrimidine kinase; Phosphomethylpyrimidine kinase type-1 1970721 10580189 Trebr_1670 Treponema brennaborense DSM 12168 Phosphomethylpyrimidine kinase type-1 YP_004440223.1 1969861 R 906968 CDS YP_004440224.1 332298302 10580190 1970826..1972355 1 NC_015500.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524; KEGG: dhd:Dhaf_1076 transcriptional regulator, GntR family with aminotransferase domain; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: uncharacterized protein; IMG reference gene:2504920578; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II; GntR family transcriptional regulator 1972355 10580190 Trebr_1671 Treponema brennaborense DSM 12168 GntR family transcriptional regulator YP_004440224.1 1970826 D 906968 CDS YP_004440225.1 332298303 10580191 complement(1972482..1974014) 1 NC_015500.1 COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: ssm:Spirs_2284 capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA; IMG reference gene:2504920579; PFAM: Bacterial capsule synthesis protein PGA_cap; capsule synthesis protein CapA 1974014 10580191 Trebr_1672 Treponema brennaborense DSM 12168 capsule synthesis protein CapA YP_004440225.1 1972482 R 906968 CDS YP_004440226.1 332298304 10580192 1974089..1975747 1 NC_015500.1 COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841:IPR008170:IPR004633; KEGG: tde:TDE1964 Na/Pi cotransporter family protein; PFAM: Na/Pi-cotransporter; PhoU; SPTR: Na/Pi cotransporter family protein; TIGRFAM: Na/Pi co-transporter II-related; manually curated; IMG reference gene:2504920580; PFAM: Na+/Pi-cotransporter; PhoU domain; TIGRFAM: Na/Pi-cotransporter; Na/Pi-cotransporter II-like protein 1975747 10580192 Trebr_1673 Treponema brennaborense DSM 12168 Na/Pi-cotransporter II-like protein YP_004440226.1 1974089 D 906968 CDS YP_004440227.1 332298305 10580193 complement(1975814..1977238) 1 NC_015500.1 COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362; KEGG: tde:TDE1499 adenylosuccinate lyase, PFAM: Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase, ; IMG reference gene:2504920581; PFAM: Lyase; Adenylosuccinate lyase 1977238 10580193 Trebr_1674 Treponema brennaborense DSM 12168 Adenylosuccinate lyase YP_004440227.1 1975814 R 906968 CDS YP_004440228.1 332298306 10580194 1977275..1978606 1 NC_015500.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: ssm:Spirs_1060 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504920582; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 1978606 10580194 Trebr_1675 Treponema brennaborense DSM 12168 signal transduction histidine kinase YP_004440228.1 1977275 D 906968 CDS YP_004440229.1 332298307 10580195 1978599..1979291 1 NC_015500.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ssm:Spirs_0377 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504920583; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; two component transcriptional regulator, LuxR family 1979291 10580195 Trebr_1676 Treponema brennaborense DSM 12168 two component transcriptional regulator, LuxR family YP_004440229.1 1978599 D 906968 CDS YP_004440230.1 332298308 10580196 1979541..1980779 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ssm:Spirs_0548 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504920584; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 1980779 10580196 Trebr_1677 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440230.1 1979541 D 906968 CDS YP_004440231.1 332298309 10580197 1980977..1981894 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_0549 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920585; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1981894 10580197 Trebr_1678 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440231.1 1980977 D 906968 CDS YP_004440232.1 332298310 10580198 1981899..1982732 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_0550 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920586; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1982732 10580198 Trebr_1679 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440232.1 1981899 D 906968 CDS YP_004440233.1 332298311 10580199 complement(1982782..1982946) 1 NC_015500.1 IMG reference gene:2504920587; hypothetical protein 1982946 10580199 Trebr_1680 Treponema brennaborense DSM 12168 hypothetical protein YP_004440233.1 1982782 R 906968 CDS YP_004440234.1 332298312 10580200 complement(1982997..1983758) 1 NC_015500.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: pva:Pvag_3503 ABC transport system, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504920588; PFAM: ABC transporter; polyamine-transporting ATPase 1983758 10580200 Trebr_1681 Treponema brennaborense DSM 12168 polyamine-transporting ATPase YP_004440234.1 1982997 R 906968 CDS YP_004440235.1 332298313 10580201 complement(1983748..1985403) 1 NC_015500.1 COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: tde:TDE0144 thiamine ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Thiamine ABC transporter, permease protein; IMG reference gene:2504920589; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 1985403 10580201 Trebr_1682 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440235.1 1983748 R 906968 CDS YP_004440236.1 332298314 10580202 complement(1985417..1986433) 1 NC_015500.1 COGs: COG4143 ABC-type thiamine transport system periplasmic component; InterPro IPR006059:IPR005948; KEGG: tde:TDE0143 thiamine ABC transporter, thiamine-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Thiamine-binding periplasmic protein; TIGRFAM: Thiamine ABC transporter periplasmic binding protein; IMG reference gene:2504920590; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily; ABC transporter substrate-binding protein 1986433 10580202 Trebr_1683 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004440236.1 1985417 R 906968 CDS YP_004440237.1 332298315 10580203 1986731..1987327 1 NC_015500.1 InterPro IPR001647; KEGG: ccb:Clocel_4085 transcriptional regulator, TetR family; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504920591; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1987327 10580203 Trebr_1684 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004440237.1 1986731 D 906968 CDS YP_004440238.1 332298316 10580204 1987337..1988737 1 NC_015500.1 COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: alpha amylase catalytic subunit; PFAM: Glycosyl hydrolase, family 13, catalytic region; PRIAM: Cyclomaltodextrinase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha-amylase 3; IMG reference gene:2504920592; PFAM: Alpha amylase, catalytic domain; Cyclomaltodextrinase 1988737 10580204 Trebr_1685 Treponema brennaborense DSM 12168 Cyclomaltodextrinase YP_004440238.1 1987337 D 906968 CDS YP_004440239.1 332298317 10580205 complement(1988891..1990276) 1 NC_015500.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: tpp:TPASS_0057 oxaloacetate decarboxylase, subunit beta; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: Oxaloacetate decarboxylase, subunit beta (OadB); TIGRFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; IMG reference gene:2504920593; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; sodium ion-translocating decarboxylase subunit beta 1990276 10580205 Trebr_1686 Treponema brennaborense DSM 12168 sodium ion-translocating decarboxylase subunit beta YP_004440239.1 1988891 R 906968 CDS YP_004440240.1 332298318 10580206 complement(1990291..1992357) 1 NC_015500.1 COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379:IPR000089:IPR005776; KEGG: tpp:TPASS_0056 pyruvate carboxylase subunit B; PFAM: Conserved carboxylase region; Pyruvate carboxyltransferase; Biotin/lipoyl attachment; PRIAM: Oxaloacetate decarboxylase; SPTR: Oxaloacetate decarboxylase alpha subunit; TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; IMG reference gene:2504920594; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain; TIGRFAM: oxaloacetate decarboxylase alpha subunit; oxaloacetate decarboxylase subunit alpha 1992357 10580206 Trebr_1687 Treponema brennaborense DSM 12168 oxaloacetate decarboxylase subunit alpha YP_004440240.1 1990291 R 906968 CDS YP_004440241.1 332298319 10580207 complement(1992375..1992617) 1 NC_015500.1 InterPro IPR005899; PFAM: Sodium ion-translocating decarboxylase; TIGRFAM: Sodium ion-translocating decarboxylase; IMG reference gene:2504920595; PFAM: Oxaloacetate decarboxylase, gamma chain; TIGRFAM: sodium pump decarboxylases, gamma subunit; sodium pump decarboxylase, gamma subunit 1992617 10580207 Trebr_1688 Treponema brennaborense DSM 12168 sodium pump decarboxylase, gamma subunit YP_004440241.1 1992375 R 906968 CDS YP_004440242.1 332298320 10580208 complement(1992778..1993557) 1 NC_015500.1 COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR000846:IPR011770; KEGG: sta:STHERM_c08680 dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: Dihydrodipicolinate reductase, bacterial/plant; IMG reference gene:2504920596; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase 1993557 10580208 Trebr_1689 Treponema brennaborense DSM 12168 dihydrodipicolinate reductase YP_004440242.1 1992778 R 906968 CDS YP_004440243.1 332298321 10580209 complement(1993554..1994900) 1 NC_015500.1 COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: ath:AT3G02020 AK3 (ASPARTATE KINASE 3); aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504920597; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; aspartate kinase 1994900 10580209 Trebr_1690 Treponema brennaborense DSM 12168 aspartate kinase YP_004440243.1 1993554 R 906968 CDS YP_004440244.1 332298322 10580210 complement(1994991..1996472) 1 NC_015500.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478:IPR011782; KEGG: tde:TDE2300 trypsin domain/PDZ domain-containing protein; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Trypsin domain/PDZ domain protein; TIGRFAM: Peptidase S1C, Do; IMG reference gene:2504920598; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; protease Do 1996472 10580210 Trebr_1691 Treponema brennaborense DSM 12168 protease Do YP_004440244.1 1994991 R 906968 CDS YP_004440245.1 332298323 10580211 complement(1996610..1997359) 1 NC_015500.1 COGs: COG0024 Methionine aminopeptidase; InterPro IPR000994:IPR002467; KEGG: tde:TDE1733 methionine aminopeptidase, type I; PFAM: Peptidase M24, structural domain; PRIAM: Methionyl aminopeptidase; SPTR: Methionine aminopeptidase; TIGRFAM: Peptidase M24A, methionine aminopeptidase, subfamily 1; IMG reference gene:2504920599; PFAM: Metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I; methionine aminopeptidase 1997359 10580211 Trebr_1692 Treponema brennaborense DSM 12168 methionine aminopeptidase YP_004440245.1 1996610 R 906968 CDS YP_004440246.1 332298324 10580212 complement(1997361..1998185) 1 NC_015500.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: tde:TDE1732 hypothetical protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: DnaJ domain protein; IMG reference gene:2504920600; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 1998185 10580212 Trebr_1693 Treponema brennaborense DSM 12168 heat shock protein DnaJ domain-containing protein YP_004440246.1 1997361 R 906968 CDS YP_004440247.1 332298325 10580213 complement(1998209..1998619) 1 NC_015500.1 KEGG: ssm:Spirs_2441 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920601; hypothetical protein 1998619 10580213 Trebr_1694 Treponema brennaborense DSM 12168 hypothetical protein YP_004440247.1 1998209 R 906968 CDS YP_004440248.1 332298326 10580214 complement(1998634..1999134) 1 NC_015500.1 InterPro IPR006016; KEGG: ssm:Spirs_3105 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein; IMG reference gene:2504920602; PFAM: Universal stress protein family; UspA domain-containing protein 1999134 10580214 Trebr_1695 Treponema brennaborense DSM 12168 UspA domain-containing protein YP_004440248.1 1998634 R 906968 CDS YP_004440249.1 332298327 10580215 complement(1999145..1999768) 1 NC_015500.1 COGs: COG1394 H+-ATPase subunit D; HAMAP: V-type ATP synthase subunit D; InterPro IPR002699; KEGG: tpp:TPASS_0527 V-type ATPase, subunit D; PFAM: ATPase, V1/A1 complex, subunit D; SPTR: V-type ATP synthase subunit D 2; TIGRFAM: ATPase, V1/A1 complex, subunit D; IMG reference gene:2504920603; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D; V-type ATP synthase subunit D 1999768 10580215 Trebr_1696 Treponema brennaborense DSM 12168 V-type ATP synthase subunit D YP_004440249.1 1999145 R 906968 CDS YP_004440250.1 332298328 10580216 complement(1999780..2001177) 1 NC_015500.1 COGs: COG1156 H+-ATPase subunit B; HAMAP: V-type ATP synthase beta chain; InterPro IPR004100:IPR000194:IPR000793; KEGG: tpp:TPASS_0528 V-type ATP synthase subunit B; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: V-type ATP synthase beta chain 2; IMG reference gene:2504920604; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; V-type ATP synthase subunit beta 2001177 10580216 Trebr_1697 Treponema brennaborense DSM 12168 V-type ATP synthase subunit beta YP_004440250.1 1999780 R 906968 CDS YP_004440251.1 332298329 10580217 complement(2001174..2002940) 1 NC_015500.1 COGs: COG1155 H+-ATPase subunit A; HAMAP: V-type ATP synthase alpha chain; InterPro IPR004100:IPR000194:IPR000793; KEGG: tpp:TPASS_0529 V-type ATP synthase subunit A; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: V-type ATP synthase alpha chain 2; IMG reference gene:2504920605; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; V-type ATP synthase subunit alpha 2002940 10580217 Trebr_1698 Treponema brennaborense DSM 12168 V-type ATP synthase subunit alpha YP_004440251.1 2001174 R 906968 CDS YP_004440252.1 332298330 10580218 complement(2002937..2003578) 1 NC_015500.1 InterPro IPR002842; KEGG: tpp:TPASS_0530 possible V-type ATPase, subunit E; PFAM: ATPase, V1/A1 complex, subunit E; SPTR: V-type ATPase, subunit E, ; IMG reference gene:2504920606; PFAM: ATP synthase (E/31 kDa) subunit; H+transporting two-sector ATPase E subunit 2003578 10580218 Trebr_1699 Treponema brennaborense DSM 12168 H+transporting two-sector ATPase E subunit YP_004440252.1 2002937 R 906968 CDS YP_004440253.1 332298331 10580219 complement(2003597..2003935) 1 NC_015500.1 InterPro IPR008218; KEGG: tpp:TPASS_0531 possible V-type ATPase, subunit F; PFAM: ATPase, V1/A1 complex, subunit F; SPTR: V-type ATPase, subunit F, ; IMG reference gene:2504920607; PFAM: ATP synthase (F/14-kDa) subunit; Vacuolar H+transporting two-sector ATPase F subunit 2003935 10580219 Trebr_1700 Treponema brennaborense DSM 12168 Vacuolar H+transporting two-sector ATPase F subunit YP_004440253.1 2003597 R 906968 CDS YP_004440254.1 332298332 10580220 complement(2003959..2004276) 1 NC_015500.1 InterPro IPR002379; KEGG: csh:Closa_4195 H+transporting two-sector ATPase C subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: H-ATPase homolog; IMG reference gene:2504920608; PFAM: ATP synthase subunit C; H+transporting two-sector ATPase subunit C 2004276 10580220 Trebr_1701 Treponema brennaborense DSM 12168 H+transporting two-sector ATPase subunit C YP_004440254.1 2003959 R 906968 CDS YP_004440255.1 332298333 10580221 complement(2004314..2006290) 1 NC_015500.1 COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: tpp:TPASS_0533 V-type ATPase, subunit I; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: V-type ATPase, subunit I; IMG reference gene:2504920609; PFAM: V-type ATPase 116kDa subunit family; V-type ATPase 116 kDa subunit 2006290 10580221 Trebr_1702 Treponema brennaborense DSM 12168 V-type ATPase 116 kDa subunit YP_004440255.1 2004314 R 906968 CDS YP_004440256.1 332298334 10580222 complement(2006306..2007307) 1 NC_015500.1 KEGG: tpp:TPASS_0534 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920610; hypothetical protein 2007307 10580222 Trebr_1703 Treponema brennaborense DSM 12168 hypothetical protein YP_004440256.1 2006306 R 906968 CDS YP_004440257.1 332298335 10580223 complement(2007375..2007680) 1 NC_015500.1 IMG reference gene:2504920611; PFAM: Vacuolar (H+)-ATPase G subunit; hypothetical protein 2007680 10580223 Trebr_1704 Treponema brennaborense DSM 12168 hypothetical protein YP_004440257.1 2007375 R 906968 CDS YP_004440258.1 332298336 10580224 complement(2007723..2008196) 1 NC_015500.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: PTS system transporter subunit IIa; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; IMG reference gene:2504920612; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 2008196 10580224 Trebr_1705 Treponema brennaborense DSM 12168 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_004440258.1 2007723 R 906968 CDS YP_004440259.1 332298337 10580225 complement(2008217..2008573) 1 NC_015500.1 COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: tde:TDE1238 preprotein translocase subunit SecG; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: Preprotein translocase SecG subunit; IMG reference gene:2504920613; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit; preprotein translocase subunit SecG 2008573 10580225 Trebr_1706 Treponema brennaborense DSM 12168 preprotein translocase subunit SecG YP_004440259.1 2008217 R 906968 CDS YP_004440260.1 332298338 10580226 complement(2008715..2009464) 1 NC_015500.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: tde:TDE1236 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase; IMG reference gene:2504920614; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; triosephosphate isomerase 2009464 10580226 Trebr_1707 Treponema brennaborense DSM 12168 triosephosphate isomerase YP_004440260.1 2008715 R 906968 CDS YP_004440261.1 332298339 10580227 2009639..2010751 1 NC_015500.1 COGs: COG3287 conserved hypothetical protein; InterPro IPR013702:IPR019494; KEGG: cbe:Cbei_2770 hypothetical protein; PFAM: FIST domain, N-terminal; FIST C domain; SPTR: uncharacterized protein; IMG reference gene:2504920615; PFAM: FIST C domain; FIST N domain; hypothetical protein 2010751 10580227 Trebr_1708 Treponema brennaborense DSM 12168 hypothetical protein YP_004440261.1 2009639 D 906968 CDS YP_004440262.1 332298340 10580228 2010767..2013358 1 NC_015500.1 COGs: COG2200 FOG: EAL domain; InterPro IPR001450:IPR007202:IPR000160:IPR001633; KEGG: ckr:CKR_1969 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Fe-S cluster; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504920616; PFAM: Iron only hydrogenase large subunit, C-terminal domain; EAL domain; Fe-S cluster; GGDEF domain; diguanylate cyclase/phosphodiesterase 2013358 10580228 Trebr_1709 Treponema brennaborense DSM 12168 diguanylate cyclase/phosphodiesterase YP_004440262.1 2010767 D 906968 CDS YP_004440263.1 332298341 10580229 complement(2013423..2014172) 1 NC_015500.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: lin:lin2436 hypothetical protein; PFAM: RNA-binding S4; Pseudouridine synthase, RsuA and RluB/C/D/E/F; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; IMG reference gene:2504920617; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; pseudouridine synthase Rsu 2014172 10580229 Trebr_1710 Treponema brennaborense DSM 12168 pseudouridine synthase Rsu YP_004440263.1 2013423 R 906968 CDS YP_004440264.1 332298342 10580230 2014246..2015049 1 NC_015500.1 COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: eca:ECA2425 pectin degradation repressor; PFAM: Transcriptional regulator IclR, C-terminal; Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal; SPTR: Pectin degradation repressor; IMG reference gene:2504920618; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator 2015049 10580230 Trebr_1711 Treponema brennaborense DSM 12168 IclR family transcriptional regulator YP_004440264.1 2014246 D 906968 CDS YP_004440265.1 332298343 10580231 complement(2015094..2016452) 1 NC_015500.1 COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: mta:Moth_1122 citrate synthase; PFAM: Citrate synthase-like; SPTR: Citrate (Si)-synthase; IMG reference gene:2504920619; PFAM: Citrate synthase; Citrate synthase 2016452 10580231 Trebr_1712 Treponema brennaborense DSM 12168 Citrate synthase YP_004440265.1 2015094 R 906968 CDS YP_004440266.1 332298344 10580232 complement(2016536..2017252) 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: tpp:TPASS_0231 hypothetical protein; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; IMG reference gene:2504920620; PFAM: RNA pseudouridylate synthase; pseudouridine synthase 2017252 10580232 Trebr_1713 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004440266.1 2016536 R 906968 CDS YP_004440267.1 332298345 10580233 2017289..2018461 1 NC_015500.1 KEGG: tde:TDE1451 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920621; hypothetical protein 2018461 10580233 Trebr_1714 Treponema brennaborense DSM 12168 hypothetical protein YP_004440267.1 2017289 D 906968 CDS YP_004440268.1 332298346 10580234 complement(2018562..2018915) 1 NC_015500.1 COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: cci:CC1G_07391 glycine-rich RNA binding protein; PFAM: RNA recognition motif, RNP-1; SMART: RNA recognition motif, RNP-1; SPTR: Glycine-rich RNA binding protein; IMG reference gene:2504920622; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); RNP-1 like RNA-binding protein 2018915 10580234 Trebr_1715 Treponema brennaborense DSM 12168 RNP-1 like RNA-binding protein YP_004440268.1 2018562 R 906968 CDS YP_004440269.1 332298347 10580235 2019159..2020118 1 NC_015500.1 COGs: COG1281 Disulfide bond chaperones of the HSP33 family; InterPro IPR000397; KEGG: tde:TDE2554 heat shock protein 34; PFAM: Heat shock protein Hsp33 protein; SPTR: Chaperonin, 33 kDa family; IMG reference gene:2504920623; PFAM: Hsp33 protein; Hsp33 protein 2020118 10580235 Trebr_1716 Treponema brennaborense DSM 12168 Hsp33 protein YP_004440269.1 2019159 D 906968 CDS YP_004440270.1 332298348 10580236 complement(2020189..2020890) 1 NC_015500.1 KEGG: tde:TDE2077 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920624; hypothetical protein 2020890 10580236 Trebr_1717 Treponema brennaborense DSM 12168 hypothetical protein YP_004440270.1 2020189 R 906968 CDS YP_004440271.1 332298349 10580237 complement(2020907..2021584) 1 NC_015500.1 InterPro IPR019734; KEGG: tde:TDE2078 TPR domain-containing protein; SPTR: TPR domain protein; IMG reference gene:2504920625; PFAM: Tetratricopeptide repeat; hypothetical protein 2021584 10580237 Trebr_1718 Treponema brennaborense DSM 12168 hypothetical protein YP_004440271.1 2020907 R 906968 CDS YP_004440272.1 332298350 10580238 complement(2021631..2023169) 1 NC_015500.1 COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterPro IPR003018:IPR002078:IPR003593; KEGG: tde:TDE2079 sigma-54 dependent transcriptional regulator, PFAM: RNA polymerase sigma factor 54, interaction; GAF; SMART: GAF; ATPase, AAA+ type, core; SPTR: Sigma-54 dependent transcriptional regulator, ; IMG reference gene:2504920626; PFAM: GAF domain; Sigma-54 interaction domain; sigma-54 interacting domain-containing protein 2023169 10580238 Trebr_1719 Treponema brennaborense DSM 12168 sigma-54 interacting domain-containing protein YP_004440272.1 2021631 R 906968 CDS YP_004440273.1 332298351 10580239 complement(2023191..2024909) 1 NC_015500.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029:IPR018032; KEGG: tde:TDE2080 cytidylate kinase/ribosomal protein S1; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: Cytidylate kinase/ribosomal protein S1; TIGRFAM: Ribosomal S1 synthesis/modification protein; IMG reference gene:2504920627; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1; 30S ribosomal protein S1 2024909 10580239 Trebr_1720 Treponema brennaborense DSM 12168 30S ribosomal protein S1 YP_004440273.1 2023191 R 906968 CDS YP_004440274.1 332298352 10580240 complement(2024919..2025551) 1 NC_015500.1 COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR011994:IPR003136; KEGG: tde:TDE2080 cytidylate kinase/ribosomal protein S1; PFAM: Cytidylate kinase region; SPTR: Cytidylate kinase/ribosomal protein S1; TIGRFAM: Cytidylate kinase; IMG reference gene:2504920628; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; cytidylate kinase 2025551 10580240 Trebr_1721 Treponema brennaborense DSM 12168 cytidylate kinase YP_004440274.1 2024919 R 906968 CDS YP_004440275.1 332298353 10580241 complement(2025561..2026334) 1 NC_015500.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: tde:TDE0875 ribosomal large subunit pseudouridine synthase B; PFAM: RNA-binding S4; Pseudouridine synthase, RsuA and RluB/C/D/E/F; SMART: RNA-binding S4; SPTR: Ribosomal large subunit pseudouridine synthase B; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; IMG reference gene:2504920629; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; pseudouridine synthase Rsu 2026334 10580241 Trebr_1722 Treponema brennaborense DSM 12168 pseudouridine synthase Rsu YP_004440275.1 2025561 R 906968 CDS YP_004440276.1 332298354 10580242 complement(2026297..2026947) 1 NC_015500.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: tde:TDE0874 transcriptional regulator, PFAM: Chromosome segregation/condensation protein ScpB, prokaryote; SPTR: Segregation and condensation protein B; TIGRFAM: Chromosome segregation/condensation protein ScpB, prokaryote; IMG reference gene:2504920630; PFAM: transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B; chromosome segregation and condensation protein ScpB 2026947 10580242 Trebr_1723 Treponema brennaborense DSM 12168 chromosome segregation and condensation protein ScpB YP_004440276.1 2026297 R 906968 CDS YP_004440277.1 332298355 10580243 complement(2026926..2027699) 1 NC_015500.1 COGs: COG1354 conserved hypothetical protein; HAMAP: Segregation and condensation protein A; InterPro IPR003768; KEGG: tde:TDE0873 hypothetical protein; PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; SPTR: uncharacterized protein; IMG reference gene:2504920631; PFAM: ScpA/B protein; segregation and condensation protein A 2027699 10580243 Trebr_1724 Treponema brennaborense DSM 12168 segregation and condensation protein A YP_004440277.1 2026926 R 906968 CDS YP_004440278.1 332298356 10580244 complement(2027772..2028449) 1 NC_015500.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: sta:STHERM_c11010 hypothetical protein; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504920632; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 2028449 10580244 Trebr_1725 Treponema brennaborense DSM 12168 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_004440278.1 2027772 R 906968 CDS YP_004440279.1 332298357 10580245 complement(2028436..2029629) 1 NC_015500.1 COGs: COG0468 RecA/RadA recombinase; HAMAP: DNA recombination and repair protein RecA; InterPro IPR013765:IPR003593; KEGG: tde:TDE0872 recombinase A; PFAM: DNA recombination and repair protein RecA; SMART: ATPase, AAA+ type, core; SPTR: Protein recA; TIGRFAM: DNA recombination and repair protein RecA; IMG reference gene:2504920633; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA; protein recA 2029629 10580245 Trebr_1726 Treponema brennaborense DSM 12168 protein recA YP_004440279.1 2028436 R 906968 CDS YP_004440280.1 332298358 10580246 complement(2029795..2030895) 1 NC_015500.1 KEGG: tde:TDE2594 hypothetical protein; SPTR: Tetratricopeptide repeat domain protein; IMG reference gene:2504920634; hypothetical protein 2030895 10580246 Trebr_1727 Treponema brennaborense DSM 12168 hypothetical protein YP_004440280.1 2029795 R 906968 CDS YP_004440281.1 332298359 10580247 complement(2030896..2031984) 1 NC_015500.1 KEGG: tde:TDE2595 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920635; hypothetical protein 2031984 10580247 Trebr_1728 Treponema brennaborense DSM 12168 hypothetical protein YP_004440281.1 2030896 R 906968 CDS YP_004440282.1 332298360 10580248 complement(2031987..2033105) 1 NC_015500.1 InterPro IPR013105; KEGG: ssm:Spirs_2047 hypothetical protein; PFAM: Tetratricopeptide TPR2; SPTR: uncharacterized protein; IMG reference gene:2504920636; hypothetical protein 2033105 10580248 Trebr_1729 Treponema brennaborense DSM 12168 hypothetical protein YP_004440282.1 2031987 R 906968 CDS YP_004440283.1 332298361 10580249 complement(2033107..2033739) 1 NC_015500.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: tpp:TPASS_0945 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504920637; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 2033739 10580249 Trebr_1730 Treponema brennaborense DSM 12168 ribulose-phosphate 3-epimerase YP_004440283.1 2033107 R 906968 CDS YP_004440284.1 332298362 10580250 2033979..2034911 1 NC_015500.1 KEGG: tde:TDE2696 TPR domain-containing protein; SPTR: TPR domain protein; IMG reference gene:2504920638; hypothetical protein 2034911 10580250 Trebr_1731 Treponema brennaborense DSM 12168 hypothetical protein YP_004440284.1 2033979 D 906968 CDS YP_004440285.1 332298363 10580251 2035038..2037737 1 NC_015500.1 COGs: COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA; InterPro IPR001437:IPR006359; KEGG: tde:TDE2695 transcript cleavage factor/unknown domain fusion protein; PFAM: Transcription elongation factor, GreA/GreB region, prokaryotic; SPTR: Transcription elongation factor; TIGRFAM: Prokaryotic transcription elongation factor GreA; IMG reference gene:2504920639; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA; transcription elongation factor GreA 2037737 10580251 Trebr_1732 Treponema brennaborense DSM 12168 transcription elongation factor GreA YP_004440285.1 2035038 D 906968 CDS YP_004440286.1 332298364 10580252 complement(2037898..2039265) 1 NC_015500.1 COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: tde:TDE1285 flagellar motor switch protein FliG, PFAM: Flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein; IMG reference gene:2504920640; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG; flagellar motor switch protein FliG 2039265 10580252 Trebr_1733 Treponema brennaborense DSM 12168 flagellar motor switch protein FliG YP_004440286.1 2037898 R 906968 CDS YP_004440287.1 332298365 10580253 2039378..2041966 1 NC_015500.1 COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: tpp:TPASS_0705 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein; TIGRFAM: Penicillin-binding protein 1A; IMG reference gene:2504920641; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; penicillin-binding protein 2041966 10580253 Trebr_1734 Treponema brennaborense DSM 12168 penicillin-binding protein YP_004440287.1 2039378 D 906968 CDS YP_004440288.1 332298366 10580254 2042004..2042411 1 NC_015500.1 InterPro IPR003115; KEGG: ssm:Spirs_1726 ParB domain protein nuclease; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB domain protein nuclease; IMG reference gene:2504920642; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; ParB domain-containing protein nuclease 2042411 10580254 Trebr_1735 Treponema brennaborense DSM 12168 ParB domain-containing protein nuclease YP_004440288.1 2042004 D 906968 CDS YP_004440289.1 332298367 10580259 complement(2048331..2048525) 1 NC_015500.1 IMG reference gene:2504920647; hypothetical protein 2048525 10580259 Trebr_1736 Treponema brennaborense DSM 12168 hypothetical protein YP_004440289.1 2048331 R 906968 CDS YP_004440290.1 332298368 10580260 complement(2048634..2049017) 1 NC_015500.1 KEGG: sta:STHERM_c08800 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920648; hypothetical protein 2049017 10580260 Trebr_1737 Treponema brennaborense DSM 12168 hypothetical protein YP_004440290.1 2048634 R 906968 CDS YP_004440291.1 332298369 10580261 complement(2049094..2053677) 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: tpp:TPASS_0854 hypothetical protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Hamp domain-containing protein; IMG reference gene:2504920649; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase with extracellular sensor 2053677 10580261 Trebr_1738 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase with extracellular sensor YP_004440291.1 2049094 R 906968 CDS YP_004440292.1 332298370 10580262 complement(2053677..2056670) 1 NC_015500.1 KEGG: tde:TDE2116 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920650; hypothetical protein 2056670 10580262 Trebr_1739 Treponema brennaborense DSM 12168 hypothetical protein YP_004440292.1 2053677 R 906968 CDS YP_004440293.1 332298371 10580263 2056819..2058099 1 NC_015500.1 InterPro IPR005362:IPR013105; KEGG: tde:TDE2117 hypothetical protein; PFAM: Uncharacterised protein family UPF0164; Tetratricopeptide TPR2; SPTR: uncharacterized protein; IMG reference gene:2504920651; PFAM: Uncharacterised protein family (UPF0164); Tetratricopeptide repeat; hypothetical protein 2058099 10580263 Trebr_1740 Treponema brennaborense DSM 12168 hypothetical protein YP_004440293.1 2056819 D 906968 CDS YP_004440294.1 332298372 10580264 complement(2058096..2059229) 1 NC_015500.1 IMG reference gene:2504920652; hypothetical protein 2059229 10580264 Trebr_1741 Treponema brennaborense DSM 12168 hypothetical protein YP_004440294.1 2058096 R 906968 CDS YP_004440295.1 332298373 10580265 complement(2059234..2060166) 1 NC_015500.1 IMG reference gene:2504920653; hypothetical protein 2060166 10580265 Trebr_1742 Treponema brennaborense DSM 12168 hypothetical protein YP_004440295.1 2059234 R 906968 CDS YP_004440296.1 332298374 10580266 complement(2060138..2061685) 1 NC_015500.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR007197:IPR006638:IPR005839:IPR 006467; KEGG: tpp:TPASS_0269 hypothetical protein; PFAM: Radical SAM; Methylthiotransferase, N-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme; Methylthiotransferase; IMG reference gene:2504920654; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family; MiaB-like tRNA modifying enzyme 2061685 10580266 Trebr_1743 Treponema brennaborense DSM 12168 MiaB-like tRNA modifying enzyme YP_004440296.1 2060138 R 906968 CDS YP_004440297.1 332298375 10580267 complement(2061645..2062283) 1 NC_015500.1 InterPro IPR001440:IPR019734; KEGG: tde:TDE1887 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920655; PFAM: Tetratricopeptide repeat; hypothetical protein 2062283 10580267 Trebr_1744 Treponema brennaborense DSM 12168 hypothetical protein YP_004440297.1 2061645 R 906968 CDS YP_004440298.1 332298376 10580268 complement(2062285..2062644) 1 NC_015500.1 COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tde:TDE1888 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: uncharacterized protein; IMG reference gene:2504920656; PFAM: Protein of unknown function, DUF583; hypothetical protein 2062644 10580268 Trebr_1745 Treponema brennaborense DSM 12168 hypothetical protein YP_004440298.1 2062285 R 906968 CDS YP_004440299.1 332298377 10580269 2062865..2063869 1 NC_015500.1 COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: tde:TDE0042 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphate acetyltransferase; TIGRFAM: Phosphate acetyltransferase; IMG reference gene:2504920657; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; phosphate acetyltransferase 2063869 10580269 Trebr_1746 Treponema brennaborense DSM 12168 phosphate acetyltransferase YP_004440299.1 2062865 D 906968 CDS YP_004440300.1 332298378 10580270 2064015..2064923 1 NC_015500.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: cce:Ccel_1156 periplasmic solute binding protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: ABC transporter, substrate-binding protein; IMG reference gene:2504920658; PFAM: Periplasmic solute binding protein family; heavy metal ABC transporter substrate-binding protein 2064923 10580270 Trebr_1747 Treponema brennaborense DSM 12168 heavy metal ABC transporter substrate-binding protein YP_004440300.1 2064015 D 906968 CDS YP_004440301.1 332298379 10580271 2065021..2065191 1 NC_015500.1 InterPro IPR001450; KEGG: tde:TDE1736 ferredoxin, 2(4Fe-4S); PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S binding domain protein; IMG reference gene:2504920659; PFAM: 4Fe-4S binding domain; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 2065191 10580271 Trebr_1748 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004440301.1 2065021 D 906968 CDS YP_004440302.1 332298380 10580272 2065283..2065714 1 NC_015500.1 KEGG: tde:TDE1737 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920660; hypothetical protein 2065714 10580272 Trebr_1749 Treponema brennaborense DSM 12168 hypothetical protein YP_004440302.1 2065283 D 906968 CDS YP_004440303.1 332298381 10580273 2065668..2066603 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047; KEGG: ssm:Spirs_1730 peptidase M23; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SPTR: Peptidase M23; IMG reference gene:2504920661; PFAM: Peptidase family M23; peptidase M23 2066603 10580273 Trebr_1750 Treponema brennaborense DSM 12168 peptidase M23 YP_004440303.1 2065668 D 906968 CDS YP_004440304.1 332298382 10580274 2066617..2067612 1 NC_015500.1 KEGG: sta:STHERM_c07170 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920662; hypothetical protein 2067612 10580274 Trebr_1751 Treponema brennaborense DSM 12168 hypothetical protein YP_004440304.1 2066617 D 906968 CDS YP_004440305.1 332298383 10580275 complement(2067750..2068565) 1 NC_015500.1 COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346; KEGG: tde:TDE0728 FAD-binding protein, PFAM: Molybdopterin dehydrogenase, FAD-binding; SPTR: FAD-binding protein; IMG reference gene:2504920663; PFAM: FAD binding domain in molybdopterin dehydrogenase; molybdopterin dehydrogenase FAD-binding protein 2068565 10580275 Trebr_1752 Treponema brennaborense DSM 12168 molybdopterin dehydrogenase FAD-binding protein YP_004440305.1 2067750 R 906968 CDS YP_004440306.1 332298384 10580276 complement(2068552..2069043) 1 NC_015500.1 COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041; KEGG: tde:TDE0727 iron-sulfur cluster-binding protein; PFAM: Ferredoxin; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504920664; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; ferredoxin 2069043 10580276 Trebr_1753 Treponema brennaborense DSM 12168 ferredoxin YP_004440306.1 2068552 R 906968 CDS YP_004440307.1 332298385 10580277 complement(2069040..2071301) 1 NC_015500.1 COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: tde:TDE0726 aldehyde oxidase and xanthine dehydrogenase family protein; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; PRIAM: Xanthine dehydrogenase; SPTR: Aldehyde oxidase and xanthine dehydrogenase family protein; IMG reference gene:2504920665; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; xanthine dehydrogenase 2071301 10580277 Trebr_1754 Treponema brennaborense DSM 12168 xanthine dehydrogenase YP_004440307.1 2069040 R 906968 CDS YP_004440308.1 332298386 10580278 complement(2071291..2072502) 1 NC_015500.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tde:TDE0725 exopolysaccharide biosynthesis protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Spore coat polysaccharide biosynthesis protein SpsC; IMG reference gene:2504920666; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase 2072502 10580278 Trebr_1755 Treponema brennaborense DSM 12168 DegT/DnrJ/EryC1/StrS aminotransferase YP_004440308.1 2071291 R 906968 CDS YP_004440309.1 332298387 10580279 complement(2072486..2073970) 1 NC_015500.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: tde:TDE0714 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Capsular polysaccharide biosynthesis protein; IMG reference gene:2504920667; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein CapD 2073970 10580279 Trebr_1756 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein CapD YP_004440309.1 2072486 R 906968 CDS YP_004440310.1 332298388 10580280 complement(2073954..2074610) 1 NC_015500.1 InterPro IPR006645:IPR005824; KEGG: tde:TDE0713 NusG family transcription antitermination protein; PFAM: Transcription antitermination protein, NusG, N-terminal; SMART: Transcription antitermination protein, NusG, N-terminal; KOW; SPTR: Transcription antitermination protein, NusG family; IMG reference gene:2504920668; PFAM: Transcription termination factor nusG; NGN domain-containing protein 2074610 10580280 Trebr_1757 Treponema brennaborense DSM 12168 NGN domain-containing protein YP_004440310.1 2073954 R 906968 CDS YP_004440311.1 332298389 10580281 2074663..2075181 1 NC_015500.1 IMG reference gene:2504920669; hypothetical protein 2075181 10580281 Trebr_1758 Treponema brennaborense DSM 12168 hypothetical protein YP_004440311.1 2074663 D 906968 CDS YP_004440312.1 332298390 10580282 2075210..2076406 1 NC_015500.1 InterPro IPR007730; KEGG: tde:TDE1185 lipoprotein; PFAM: Sporulation/cell division region, bacteria; SPTR: Lipoprotein, ; IMG reference gene:2504920670; sporulation domain-containing protein 2076406 10580282 Trebr_1759 Treponema brennaborense DSM 12168 sporulation domain-containing protein YP_004440312.1 2075210 D 906968 CDS YP_004440313.1 332298391 10580283 complement(2076492..2077772) 1 NC_015500.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835:IPR011831; KEGG: tde:TDE2035 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase; TIGRFAM: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2504920671; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; glucose-1-phosphate adenylyltransferase 2077772 10580283 Trebr_1760 Treponema brennaborense DSM 12168 glucose-1-phosphate adenylyltransferase YP_004440313.1 2076492 R 906968 CDS YP_004440314.1 332298392 10580284 2077972..2078856 1 NC_015500.1 COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: protein of unknown function DUF6 transmembrane; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Drug/metabolite transporter; IMG reference gene:2504920672; PFAM: EamA-like transporter family; hypothetical protein 2078856 10580284 Trebr_1761 Treponema brennaborense DSM 12168 hypothetical protein YP_004440314.1 2077972 D 906968 CDS YP_004440315.1 332298393 10580285 complement(2078955..2080325) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: elm:ELI_0476 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; manually curated; IMG reference gene:2504920673; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 2080325 10580285 Trebr_1762 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004440315.1 2078955 R 906968 CDS YP_004440316.1 332298394 10580286 2080488..2082023 1 NC_015500.1 KEGG: ssm:Spirs_1830 PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504920674; PFAM: PPIC-type PPIASE domain; PpiC-type peptidyl-prolyl cis-trans isomerase 2082023 10580286 Trebr_1763 Treponema brennaborense DSM 12168 PpiC-type peptidyl-prolyl cis-trans isomerase YP_004440316.1 2080488 D 906968 CDS YP_004440317.1 332298395 10580287 2082030..2083769 1 NC_015500.1 InterPro IPR002826; KEGG: tde:TDE2525 hypothetical protein; PFAM: Protein of unknown function DUF115; SPTR: uncharacterized protein; IMG reference gene:2504920675; PFAM: Protein of unknown function DUF115; hypothetical protein 2083769 10580287 Trebr_1764 Treponema brennaborense DSM 12168 hypothetical protein YP_004440317.1 2082030 D 906968 CDS YP_004440318.1 332298396 10580288 complement(2083862..2085667) 1 NC_015500.1 COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein lepA; InterProIPR000795:IPR004161:IPR000640:IPR013842:IPR 005225:IPR006297; KEGG: tde:TDE1893 GTP-binding protein LepA; PFAM: GTP-binding protein LepA, C-terminal; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor 4; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein; IMG reference gene:2504920676; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain; GTP-binding protein lepA 2085667 10580288 Trebr_1765 Treponema brennaborense DSM 12168 GTP-binding protein lepA YP_004440318.1 2083862 R 906968 CDS YP_004440319.1 332298397 10580289 complement(2085842..2087530) 1 NC_015500.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478; KEGG: tpp:TPASS_0546 possible periplasmic serine protease; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Trypsin domain/PDZ domain protein; IMG reference gene:2504920677; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); peptidase S1 and S6 chymotrypsin/Hap 2087530 10580289 Trebr_1766 Treponema brennaborense DSM 12168 peptidase S1 and S6 chymotrypsin/Hap YP_004440319.1 2085842 R 906968 CDS YP_004440320.1 332298398 10580290 complement(2087523..2089634) 1 NC_015500.1 KEGG: tpp:TPASS_0374 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920678; hypothetical protein 2089634 10580290 Trebr_1767 Treponema brennaborense DSM 12168 hypothetical protein YP_004440320.1 2087523 R 906968 CDS YP_004440321.1 332298399 10580291 complement(2089661..2091511) 1 NC_015500.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR011546:IPR003959:IPR000642:IPR003593:IPR 005936; KEGG: ssm:Spirs_1817 ATP-dependent metalloprotease FtsH; PFAM: Peptidase M41; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504920679; PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; ATP-dependent metalloprotease FtsH 2091511 10580291 Trebr_1768 Treponema brennaborense DSM 12168 ATP-dependent metalloprotease FtsH YP_004440321.1 2089661 R 906968 CDS YP_004440322.1 332298400 10580292 complement(2091579..2093048) 1 NC_015500.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: tRNA(Ile)-lysidine synthase; InterPro IPR011063:IPR012795:IPR012796; KEGG: tde:TDE1341 hypothetical protein; PFAM: PP-loop; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: Lysidine-tRNA(Ile) synthetase, N-terminal; Lysidine-tRNA(Ile) synthetase, C-terminal; IMG reference gene:2504920680; PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain; tRNA(Ile)-lysidine synthase 2093048 10580292 Trebr_1769 Treponema brennaborense DSM 12168 tRNA(Ile)-lysidine synthase YP_004440322.1 2091579 R 906968 CDS YP_004440323.1 332298401 10580293 complement(2093122..2093679) 1 NC_015500.1 COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); HAMAP: Ribosomal protein L25; InterPro IPR020055:IPR001021; KEGG: tde:TDE1340 50S ribosomal protein L25/general stress protein Ctc; PFAM: Ribosomal protein L25, N-terminal; SPTR: 50S ribosomal protein L25; TIGRFAM: Ribosomal protein L25; IMG reference gene:2504920681; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form; 50S ribosomal protein L25 2093679 10580293 Trebr_1770 Treponema brennaborense DSM 12168 50S ribosomal protein L25 YP_004440323.1 2093122 R 906968 CDS YP_004440324.1 332298402 10580295 complement(2093829..2094119) 1 NC_015500.1 COGs: COG2088 Uncharacterized protein involved in the regulation of septum location; HAMAP: septation protein spoVG; InterPro IPR007170; KEGG: ssm:Spirs_1813 SpoVG family protein; PFAM: Sporulation stage V, protein G; SPTR: SpoVG family protein; IMG reference gene:2504920683; PFAM: SpoVG; septation protein spoVG 2094119 10580295 Trebr_1771 Treponema brennaborense DSM 12168 septation protein spoVG YP_004440324.1 2093829 R 906968 CDS YP_004440325.1 332298403 10580296 complement(2094170..2095156) 1 NC_015500.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; InterPro IPR006204:IPR004424; KEGG: tde:TDE1338 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR: 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; IMG reference gene:2504920684; PFAM: GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2095156 10580296 Trebr_1772 Treponema brennaborense DSM 12168 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_004440325.1 2094170 R 906968 CDS YP_004440326.1 332298404 10580297 2095215..2095469 1 NC_015500.1 KEGG: tde:TDE2071 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920685; hypothetical protein 2095469 10580297 Trebr_1773 Treponema brennaborense DSM 12168 hypothetical protein YP_004440326.1 2095215 D 906968 CDS YP_004440327.1 332298405 10580298 complement(2095552..2095896) 1 NC_015500.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: tde:TDE1745 hypothetical protein; PFAM: Iojap-related protein; SPTR: uncharacterized protein; TIGRFAM: Iojap-related protein; IMG reference gene:2504920686; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein; iojap family protein 2095896 10580298 Trebr_1774 Treponema brennaborense DSM 12168 iojap family protein YP_004440327.1 2095552 R 906968 CDS YP_004440328.1 332298406 10580299 complement(2095928..2097127) 1 NC_015500.1 COGs: COG1316 Transcriptional regulator; KEGG: tpp:TPASS_0739 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920687; PFAM: Cell envelope-related transcriptional attenuator domain; hypothetical protein 2097127 10580299 Trebr_1775 Treponema brennaborense DSM 12168 hypothetical protein YP_004440328.1 2095928 R 906968 CDS YP_004440329.1 332298407 10580300 complement(2097127..2097693) 1 NC_015500.1 COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR006674:IPR003607:IPR005249; KEGG: tde:TDE1747 nicotinate-nucleotide adenylyltransferase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: Conserved hypothetical protein CHP00488; IMG reference gene:2504920688; PFAM: HD domain; TIGRFAM: HD superfamily hydrolase of NAD metabolism; metal dependent phosphohydrolase 2097693 10580300 Trebr_1776 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004440329.1 2097127 R 906968 CDS YP_004440330.1 332298408 10580301 complement(2097674..2098321) 1 NC_015500.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; HAMAP: nicotinate-nucleotide adenylyltransferase; InterPro IPR004820:IPR004821:IPR005248; KEGG: sta:STHERM_c10300 nicotinate-nucleotide adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: Probable nicotinate-nucleotide adenylyltransferase; Cytidyltransferase-related; IMG reference gene:2504920689; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain; nicotinate-nucleotide adenylyltransferase 2098321 10580301 Trebr_1777 Treponema brennaborense DSM 12168 nicotinate-nucleotide adenylyltransferase YP_004440330.1 2097674 R 906968 CDS YP_004440331.1 332298409 10580302 complement(2098326..2099471) 1 NC_015500.1 COGs: COG0536 GTPase; HAMAP: GTPase obg; InterPro IPR006169:IPR002917:IPR014100; KEGG: tde:TDE1748 GTPase ObgE; PFAM: GTP1/OBG subdomain; GTP-binding protein, HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; IMG reference gene:2504920690; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; GTPase obg 2099471 10580302 Trebr_1778 Treponema brennaborense DSM 12168 GTPase obg YP_004440331.1 2098326 R 906968 CDS YP_004440332.1 332298410 10580303 complement(2099553..2099810) 1 NC_015500.1 COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: tde:TDE1749 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; IMG reference gene:2504920691; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; 50S ribosomal protein L27 2099810 10580303 Trebr_1779 Treponema brennaborense DSM 12168 50S ribosomal protein L27 YP_004440332.1 2099553 R 906968 CDS YP_004440333.1 332298411 10580304 complement(2099826..2100161) 1 NC_015500.1 COGs: COG2868 ribosomal protein; InterPro IPR007422; KEGG: tpp:TPASS_0744 hypothetical protein; PFAM: Protein of unknown function DUF464; SPTR: uncharacterized protein; IMG reference gene:2504920692; PFAM: Protein of unknown function (DUF464); hypothetical protein 2100161 10580304 Trebr_1780 Treponema brennaborense DSM 12168 hypothetical protein YP_004440333.1 2099826 R 906968 CDS YP_004440334.1 332298412 10580305 complement(2100168..2100482) 1 NC_015500.1 COGs: COG0261 Ribosomal protein L21; HAMAP: Ribosomal protein L21; InterPro IPR001787; KEGG: tde:TDE1751 50S ribosomal protein L21; PFAM: Ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: Ribosomal protein L21; IMG reference gene:2504920693; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21; 50S ribosomal protein L21 2100482 10580305 Trebr_1781 Treponema brennaborense DSM 12168 50S ribosomal protein L21 YP_004440334.1 2100168 R 906968 CDS YP_004440335.1 332298413 10580306 2100912..2101613 1 NC_015500.1 KEGG: cac:CA_C2107 cell adhesion domain-containing protein; SPTR: Contains cell adhesion domain; IMG reference gene:2504920694; hypothetical protein 2101613 10580306 Trebr_1782 Treponema brennaborense DSM 12168 hypothetical protein YP_004440335.1 2100912 D 906968 CDS YP_004440336.1 332298414 10580307 complement(2101564..2102409) 1 NC_015500.1 IMG reference gene:2504920695; hypothetical protein 2102409 10580307 Trebr_1783 Treponema brennaborense DSM 12168 hypothetical protein YP_004440336.1 2101564 R 906968 CDS YP_004440337.1 332298415 10580308 complement(2102596..2102853) 1 NC_015500.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR007712:IPR012753; KEGG: tde:TDE0735 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: uncharacterized protein; TIGRFAM: Addiction module toxin, RelE/StbE; manually curated; IMG reference gene:2504920696; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family; RelE/StbE family addiction module toxin 2102853 10580308 Trebr_1784 Treponema brennaborense DSM 12168 RelE/StbE family addiction module toxin YP_004440337.1 2102596 R 906968 CDS YP_004440338.1 332298416 10580309 complement(2102850..2103086) 1 NC_015500.1 KEGG: tde:TDE1979 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920697; hypothetical protein 2103086 10580309 Trebr_1785 Treponema brennaborense DSM 12168 hypothetical protein YP_004440338.1 2102850 R 906968 CDS YP_004440339.1 332298417 10580310 complement(2103399..2104091) 1 NC_015500.1 IMG reference gene:2504920698; hypothetical protein 2104091 10580310 Trebr_1786 Treponema brennaborense DSM 12168 hypothetical protein YP_004440339.1 2103399 R 906968 CDS YP_004440340.1 332298418 10580311 complement(2104145..2105062) 1 NC_015500.1 KEGG: ssm:Spirs_2159 integrase family protein; SPTR: Integrase family protein; IMG reference gene:2504920699; hypothetical protein 2105062 10580311 Trebr_1787 Treponema brennaborense DSM 12168 hypothetical protein YP_004440340.1 2104145 R 906968 CDS YP_004440341.1 332298419 10580314 2105483..2107582 1 NC_015500.1 COGs: COG3509 Poly(3-hydroxybutyrate) depolymerase; InterPro IPR002818:IPR000421; KEGG: hoh:Hoch_1480 coagulation factor 5/8 type domain protein; PFAM: Coagulation factor 5/8 type, C-terminal; ThiJ/PfpI; SPTR: Coagulation factor 5/8 type domain protein; IMG reference gene:2504920702; PFAM: F5/8 type C domain; DJ-1/PfpI family; coagulation factor 5/8 type domain-containing protein 2107582 10580314 Trebr_1788 Treponema brennaborense DSM 12168 coagulation factor 5/8 type domain-containing protein YP_004440341.1 2105483 D 906968 CDS YP_004440342.1 332298420 10580315 2107676..2109466 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: elm:ELI_4404 ABC transporter related protein; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504920703; PFAM: ABC transporter transmembrane region; ABC transporter; xenobiotic-transporting ATPase 2109466 10580315 Trebr_1789 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004440342.1 2107676 D 906968 CDS YP_004440343.1 332298421 10580316 2109466..2111385 1 NC_015500.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: elm:ELI_4405 ABC-type multidrug transport system; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type multidrug transport system; IMG reference gene:2504920704; PFAM: ABC transporter transmembrane region; ABC transporter; xenobiotic-transporting ATPase 2111385 10580316 Trebr_1790 Treponema brennaborense DSM 12168 xenobiotic-transporting ATPase YP_004440343.1 2109466 D 906968 CDS YP_004440344.1 332298422 10580317 complement(2111394..2112305) 1 NC_015500.1 COGs: COG2378 transcriptional regulator protein; InterPro IPR013196; KEGG: cpy:Cphy_0991 helix-turn-helix type 11 domain-containing protein; SPTR: transcriptional regulator; IMG reference gene:2504920705; PFAM: HTH domain; helix-turn-helix type 11 domain-containing protein 2112305 10580317 Trebr_1791 Treponema brennaborense DSM 12168 helix-turn-helix type 11 domain-containing protein YP_004440344.1 2111394 R 906968 CDS YP_004440345.1 332298423 10580318 2112975..2113562 1 NC_015500.1 InterPro IPR001387; KEGG: dhd:Dhaf_1789 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: uncharacterized protein; IMG reference gene:2504920706; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2113562 10580318 Trebr_1792 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440345.1 2112975 D 906968 CDS YP_004440346.1 332298424 10580319 complement(2113568..2114440) 1 NC_015500.1 COGs: COG1533 DNA repair photolyase; InterPro IPR007197; KEGG: mla:Mlab_0619 hypothetical protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504920707; PFAM: Radical SAM superfamily; Radical SAM domain protein 2114440 10580319 Trebr_1793 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004440346.1 2113568 R 906968 CDS YP_004440347.1 332298425 10580320 complement(2114455..2116110) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE0178 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504920708; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2116110 10580320 Trebr_1794 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440347.1 2114455 R 906968 CDS YP_004440348.1 332298426 10580321 2116297..2117421 1 NC_015500.1 InterPro IPR000182:IPR013217; KEGG: csh:Closa_3290 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Methyltransferase type 12; SPTR: uncharacterized protein; IMG reference gene:2504920709; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 2117421 10580321 Trebr_1795 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004440348.1 2116297 D 906968 CDS YP_004440349.1 332298427 10580322 2117911..2118774 1 NC_015500.1 InterPro IPR010106; KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504920710; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 2118774 10580322 Trebr_1796 Treponema brennaborense DSM 12168 hypothetical protein YP_004440349.1 2117911 D 906968 CDS YP_004440350.1 332298428 10580323 complement(2118808..2119047) 1 NC_015500.1 IMG reference gene:2504920711; hypothetical protein 2119047 10580323 Trebr_1797 Treponema brennaborense DSM 12168 hypothetical protein YP_004440350.1 2118808 R 906968 CDS YP_004440351.1 332298429 10580325 complement(2119571..2120797) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: pru:PRU_0104 group 1 family glycosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyltransferase, group 1 family; IMG reference gene:2504920713; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2120797 10580325 Trebr_1799 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440351.1 2119571 R 906968 CDS YP_004440352.1 332298430 10580326 complement(2120925..2121314) 1 NC_015500.1 KEGG: bvu:BVU_1541 hypothetical protein; SPTR: Mannose-6-phosphate isomerase; IMG reference gene:2504920714; PFAM: Cupin domain; hypothetical protein 2121314 10580326 Trebr_1800 Treponema brennaborense DSM 12168 hypothetical protein YP_004440352.1 2120925 R 906968 CDS YP_004440353.1 332298431 10580327 complement(2121311..2122453) 1 NC_015500.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; IMG reference gene:2504920715; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 2122453 10580327 Trebr_1801 Treponema brennaborense DSM 12168 UDP-N-acetylglucosamine 2-epimerase YP_004440353.1 2121311 R 906968 CDS YP_004440354.1 332298432 10580328 complement(2122460..2123341) 1 NC_015500.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR001509; KEGG: bfr:BF2569 reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Carbohydrate oxidoreductase; manually curated; IMG reference gene:2504920716; PFAM: RmlD substrate binding domain; NAD-dependent epimerase/dehydratase 2123341 10580328 Trebr_1802 Treponema brennaborense DSM 12168 NAD-dependent epimerase/dehydratase YP_004440354.1 2122460 R 906968 CDS YP_004440355.1 332298433 10580330 complement(2123676..2124917) 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504920718; PFAM: Transposase, Mutator family; transposase mutator type 2124917 10580330 Trebr_1804 Treponema brennaborense DSM 12168 transposase mutator type YP_004440355.1 2123676 R 906968 CDS YP_004440356.1 332298434 10580331 complement(2125977..2126816) 1 NC_015500.1 InterPro IPR014942; KEGG: dak:DaAHT2_0326 domain of unknown function DUF1814; PFAM: Protein of unknown function DUF1814; SPTR: uncharacterized protein; IMG reference gene:2504920719; PFAM: Domain of unknown function (DUF1814); hypothetical protein 2126816 10580331 Trebr_1805 Treponema brennaborense DSM 12168 hypothetical protein YP_004440356.1 2125977 R 906968 CDS YP_004440357.1 332298435 10580332 complement(2126803..2127435) 1 NC_015500.1 KEGG: dak:DaAHT2_0325 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920720; hypothetical protein 2127435 10580332 Trebr_1806 Treponema brennaborense DSM 12168 hypothetical protein YP_004440357.1 2126803 R 906968 CDS YP_004440358.1 332298436 10580333 complement(2127417..2128586) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: llo:LLO_0232 glycosyltransferase, lipopolysaccharide biosynthesis protein; PFAM: Glycosyl transferase, group 1; SPTR: WfbF; IMG reference gene:2504920721; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2128586 10580333 Trebr_1807 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440358.1 2127417 R 906968 CDS YP_004440359.1 332298437 10580334 complement(2128674..2129726) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ypy:YPK_3184 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase; IMG reference gene:2504920722; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2129726 10580334 Trebr_1808 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440359.1 2128674 R 906968 CDS YP_004440360.1 332298438 10580335 complement(2130100..2131272) 1 NC_015500.1 KEGG: llk:LLKF_0137 polysaccharide biosynthesis protein; SPTR: Predicted protein; IMG reference gene:2504920723; hypothetical protein 2131272 10580335 Trebr_1809 Treponema brennaborense DSM 12168 hypothetical protein YP_004440360.1 2130100 R 906968 CDS YP_004440361.1 332298439 10580336 complement(2131277..2132365) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: pgn:PGN_1251 probable glycosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: WfaQ; IMG reference gene:2504920724; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2132365 10580336 Trebr_1810 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440361.1 2131277 R 906968 CDS YP_004440362.1 332298440 10580337 complement(2132372..2133472) 1 NC_015500.1 KEGG: stl:stu1102 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920725; PFAM: Polysaccharide pyruvyl transferase; hypothetical protein 2133472 10580337 Trebr_1811 Treponema brennaborense DSM 12168 hypothetical protein YP_004440362.1 2132372 R 906968 CDS YP_004440363.1 332298441 10580338 complement(2133681..2134865) 1 NC_015500.1 COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR001450:IPR007525; KEGG: bpb:bpr_I0816 coenzyme F420-reducing hydrogenase beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; SPTR: Coenzyme F420-reducing hydrogenase beta subunit; IMG reference gene:2504920726; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 2134865 10580338 Trebr_1812 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004440363.1 2133681 R 906968 CDS YP_004440364.1 332298442 10580339 complement(2134862..2136553) 1 NC_015500.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002528; KEGG: pdi:BDI_1846 transmembrane protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: Conserved hypothetical transmembrane protein; transmembrane protein; IMG reference gene:2504920727; PFAM: MatE; multi antimicrobial extrusion protein MatE 2136553 10580339 Trebr_1813 Treponema brennaborense DSM 12168 multi antimicrobial extrusion protein MatE YP_004440364.1 2134862 R 906968 CDS YP_004440365.1 332298443 10580340 2136887..2137360 1 NC_015500.1 COGs: COG1438 Arginine repressor; HAMAP: Arginine repressor; InterPro IPR001669; KEGG: ssm:Spirs_3243 arginine repressor, ArgR; PFAM: Arginine repressor; SPTR: Arginine repressor; IMG reference gene:2504920728; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor; arginine repressor ArgR 2137360 10580340 Trebr_1814 Treponema brennaborense DSM 12168 arginine repressor ArgR YP_004440365.1 2136887 D 906968 CDS YP_004440366.1 332298444 10580341 complement(2137426..2138139) 1 NC_015500.1 KEGG: elm:ELI_3508 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920729; hypothetical protein 2138139 10580341 Trebr_1815 Treponema brennaborense DSM 12168 hypothetical protein YP_004440366.1 2137426 R 906968 CDS YP_004440367.1 332298445 10580342 complement(2138136..2138849) 1 NC_015500.1 KEGG: bpb:bpr_III149 ABC transporter permease; SPTR: ABC transporter permease protein; IMG reference gene:2504920730; ABC transporter permease 2138849 10580342 Trebr_1816 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440367.1 2138136 R 906968 CDS YP_004440368.1 332298446 10580343 complement(2138846..2139769) 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: bpb:bpr_III150 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504920731; PFAM: ABC transporter; ABC transporter 2139769 10580343 Trebr_1817 Treponema brennaborense DSM 12168 ABC transporter YP_004440368.1 2138846 R 906968 CDS YP_004440369.1 332298447 10580344 complement(2139779..2140393) 1 NC_015500.1 InterPro IPR001647; KEGG: elm:ELI_3511 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: TetR family transcriptional regulator; IMG reference gene:2504920732; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 2140393 10580344 Trebr_1818 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004440369.1 2139779 R 906968 CDS YP_004440370.1 332298448 10580345 2140671..2142254 1 NC_015500.1 COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: eel:EUBELI_00049 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504920733; PFAM: Phosphoglucose isomerase; glucose-6-phosphate isomerase 2142254 10580345 Trebr_1819 Treponema brennaborense DSM 12168 glucose-6-phosphate isomerase YP_004440370.1 2140671 D 906968 CDS YP_004440371.1 332298449 10580346 2142474..2143373 1 NC_015500.1 COGs: COG2035 membrane protein; InterPro IPR007163; KEGG: tde:TDE2250 hypothetical protein; PFAM: Protein of unknown function DUF368; SPTR: Integral membrane protein; IMG reference gene:2504920734; PFAM: Domain of unknown function (DUF368); hypothetical protein 2143373 10580346 Trebr_1820 Treponema brennaborense DSM 12168 hypothetical protein YP_004440371.1 2142474 D 906968 CDS YP_004440372.1 332298450 10580347 complement(2143548..2144405) 1 NC_015500.1 KEGG: tde:TDE2640 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920735; PFAM: Peptidase family M28; hypothetical protein 2144405 10580347 Trebr_1821 Treponema brennaborense DSM 12168 hypothetical protein YP_004440372.1 2143548 R 906968 CDS YP_004440373.1 332298451 10580348 complement(2144455..2144895) 1 NC_015500.1 KEGG: cbl:CLK_0205 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920736; hypothetical protein 2144895 10580348 Trebr_1822 Treponema brennaborense DSM 12168 hypothetical protein YP_004440373.1 2144455 R 906968 CDS YP_004440374.1 332298452 10580349 2145056..2146327 1 NC_015500.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004843:IPR004593; KEGG: tde:TDE0170 nuclease SbcCD, D subunit, PFAM: Metallophosphoesterase; SPTR: Nuclease SbcCD, D subunit, ; TIGRFAM: Exonuclease SbcD; IMG reference gene:2504920737; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD; nuclease SbcCD subunit D 2146327 10580349 Trebr_1823 Treponema brennaborense DSM 12168 nuclease SbcCD subunit D YP_004440374.1 2145056 D 906968 CDS YP_004440375.1 332298453 10580350 2146324..2149416 1 NC_015500.1 COGs: COG0419 ATPase involved in DNA repair; KEGG: tpp:TPASS_0627 exonuclease; SPTR: SMC domain protein; IMG reference gene:2504920738; TIGRFAM: exonuclease SbcC; exonuclease 2149416 10580350 Trebr_1824 Treponema brennaborense DSM 12168 exonuclease YP_004440375.1 2146324 D 906968 CDS YP_004440376.1 332298454 10580351 complement(2149461..2150276) 1 NC_015500.1 KEGG: ccb:Clocel_0911 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920739; hypothetical protein 2150276 10580351 Trebr_1825 Treponema brennaborense DSM 12168 hypothetical protein YP_004440376.1 2149461 R 906968 CDS YP_004440377.1 332298455 10580352 2150508..2152013 1 NC_015500.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644; KEGG: cbe:Cbei_2114 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SMART: Cystathionine beta-synthase, core; SPTR: IMP dehydrogenase; IMG reference gene:2504920740; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase 2152013 10580352 Trebr_1826 Treponema brennaborense DSM 12168 IMP dehydrogenase YP_004440377.1 2150508 D 906968 CDS YP_004440378.1 332298456 10580353 complement(2152116..2153552) 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: gau:GAU_3690 ribosomal large subunit pseudouridine synthase A; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; IMG reference gene:2504920741; PFAM: RNA pseudouridylate synthase; pseudouridine synthase 2153552 10580353 Trebr_1827 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004440378.1 2152116 R 906968 CDS YP_004440379.1 332298457 10580354 complement(2153580..2154596) 1 NC_015500.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; HAMAP: O-sialoglycoprotein endopeptidase; InterPro IPR000905:IPR017861; KEGG: tde:TDE2504 DNA-binding/iron metalloprotein/AP endonuclease; PFAM: Peptidase M22, glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: Probable O-sialoglycoprotein endopeptidase; TIGRFAM: glycoprotease GCP; Peptidase M22, glycoprotease, subgroup; IMG reference gene:2504920742; PFAM: Glycoprotease family; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family; O-sialoglycoprotein endopeptidase 2154596 10580354 Trebr_1828 Treponema brennaborense DSM 12168 O-sialoglycoprotein endopeptidase YP_004440379.1 2153580 R 906968 CDS YP_004440380.1 332298458 10580355 complement(2154577..2155644) 1 NC_015500.1 COGs: COG2861 conserved hypothetical protein; InterPro IPR006837; KEGG: tde:TDE2503 hypothetical protein; PFAM: Protein of unknown function DUF610, YibQ; SPTR: Conserved domain protein; IMG reference gene:2504920743; PFAM: Divergent polysaccharide deacetylase; hypothetical protein 2155644 10580355 Trebr_1829 Treponema brennaborense DSM 12168 hypothetical protein YP_004440380.1 2154577 R 906968 CDS YP_004440381.1 332298459 10580356 2155884..2156054 1 NC_015500.1 KEGG: tde:TDE2408 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920744; hypothetical protein 2156054 10580356 Trebr_1830 Treponema brennaborense DSM 12168 hypothetical protein YP_004440381.1 2155884 D 906968 CDS YP_004440382.1 332298460 10580357 complement(2156132..2156890) 1 NC_015500.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tde:TDE1989 acyltransferase family protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Acyltransferase family protein; IMG reference gene:2504920745; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase 2156890 10580357 Trebr_1831 Treponema brennaborense DSM 12168 phospholipid/glycerol acyltransferase YP_004440382.1 2156132 R 906968 CDS YP_004440383.1 332298461 10580358 complement(2156978..2159434) 1 NC_015500.1 COGs: COG1199 Rad3-related DNA helicase; InterPro IPR006555; KEGG: ssm:Spirs_1712 helicase C2; SMART: Helicase, ATP-dependent, c2 type; SPTR: Helicase c2; IMG reference gene:2504920746; PFAM: Protein of unknown function (DUF2466); helicase c2 2159434 10580358 Trebr_1832 Treponema brennaborense DSM 12168 helicase c2 YP_004440383.1 2156978 R 906968 CDS YP_004440384.1 332298462 10580360 complement(2159654..2160895) 1 NC_015500.1 COGs: COG2357 conserved hypothetical protein; InterPro IPR007685:IPR001440:IPR019734; KEGG: tde:TDE1711 RelA/SpoT domain-containing protein; PFAM: RelA/SpoT; Tetratricopeptide TPR-1; SPTR: RelA/SpoT domain protein; IMG reference gene:2504920748; PFAM: Region found in RelA / SpoT proteins; Tetratricopeptide repeat; RelA/SpoT domain-containing protein 2160895 10580360 Trebr_1833 Treponema brennaborense DSM 12168 RelA/SpoT domain-containing protein YP_004440384.1 2159654 R 906968 CDS YP_004440385.1 332298463 10580361 complement(2161064..2162113) 1 NC_015500.1 InterPro IPR006714; KEGG: tde:TDE1712 flagellar filament outer layer protein; PFAM: Flagellar filament outer layer protein FlaA; SPTR: Flagellar filament outer layer protein; IMG reference gene:2504920749; PFAM: Flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA 2162113 10580361 Trebr_1834 Treponema brennaborense DSM 12168 flagellar filament outer layer protein FlaA YP_004440385.1 2161064 R 906968 CDS YP_004440386.1 332298464 10580362 complement(2162229..2162723) 1 NC_015500.1 InterPro IPR019606; KEGG: ssm:Spirs_2927 lipoprotein LpqB, GerMN domain protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: uncharacterized protein; IMG reference gene:2504920750; PFAM: Sporulation and spore germination; Lipoprotein LpqB, GerMN domain-containing protein 2162723 10580362 Trebr_1835 Treponema brennaborense DSM 12168 Lipoprotein LpqB, GerMN domain-containing protein YP_004440386.1 2162229 R 906968 CDS YP_004440387.1 332298465 10580363 complement(2162720..2163754) 1 NC_015500.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: tde:TDE1714 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase, family 3; IMG reference gene:2504920751; PFAM: N-acetylmuramoyl-L-alanine amidase; cell wall hydrolase/autolysin 2163754 10580363 Trebr_1836 Treponema brennaborense DSM 12168 cell wall hydrolase/autolysin YP_004440387.1 2162720 R 906968 CDS YP_004440388.1 332298466 10580364 complement(2163751..2165442) 1 NC_015500.1 COGs: COG0439 Biotin carboxylase; InterPro IPR003806; KEGG: tde:TDE2209 CarB family protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: CarB family protein; IMG reference gene:2504920752; PFAM: ATP-grasp domain; ATP-grasp fold domain-containing protein 2165442 10580364 Trebr_1837 Treponema brennaborense DSM 12168 ATP-grasp fold domain-containing protein YP_004440388.1 2163751 R 906968 CDS YP_004440389.1 332298467 10580365 complement(2165450..2167984) 1 NC_015500.1 COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329:IPR013217; KEGG: tde:TDE1917 cytidyltransferase-like protein; PFAM: Acylneuraminate cytidylyltransferase; Methyltransferase type 12; SPTR: Cytidylyltransferase domain protein; IMG reference gene:2504920753; PFAM: Methyltransferase domain; Cytidylyltransferase; acylneuraminate cytidylyltransferase 2167984 10580365 Trebr_1838 Treponema brennaborense DSM 12168 acylneuraminate cytidylyltransferase YP_004440389.1 2165450 R 906968 CDS YP_004440390.1 332298468 10580366 complement(2167981..2168973) 1 NC_015500.1 KEGG: tde:TDE1918 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920754; hypothetical protein 2168973 10580366 Trebr_1839 Treponema brennaborense DSM 12168 hypothetical protein YP_004440390.1 2167981 R 906968 CDS YP_004440391.1 332298469 10580367 complement(2168948..2170618) 1 NC_015500.1 InterPro IPR007197; KEGG: ssm:Spirs_2933 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504920755; PFAM: Radical SAM superfamily; Radical SAM domain protein 2170618 10580367 Trebr_1840 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004440391.1 2168948 R 906968 CDS YP_004440392.1 332298470 10580368 2170668..2172485 1 NC_015500.1 COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: ate:Athe_0165 alpha amylase catalytic domain-containing protein; PFAM: Glycosyl hydrolase, family 13, catalytic region; PRIAM: Oligo-1,6-glucosidase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region; IMG reference gene:2504920756; PFAM: Alpha amylase, catalytic domain; oligo-1,6-glucosidase 2172485 10580368 Trebr_1841 Treponema brennaborense DSM 12168 oligo-1,6-glucosidase YP_004440392.1 2170668 D 906968 CDS YP_004440393.1 332298471 10580369 2172482..2173708 1 NC_015500.1 COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exodeoxyribonuclease 7 large subunit; InterPro IPR003753:IPR004365:IPR020579; KEGG: tde:TDE1017 exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Exodeoxyribonuclease VII; SPTR: Exodeoxyribonuclease 7 large subunit; TIGRFAM: Exonuclease VII, large subunit; IMG reference gene:2504920757; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit; exodeoxyribonuclease 7 large subunit 2173708 10580369 Trebr_1842 Treponema brennaborense DSM 12168 exodeoxyribonuclease 7 large subunit YP_004440393.1 2172482 D 906968 CDS YP_004440394.1 332298472 10580370 2173735..2173974 1 NC_015500.1 HAMAP: Exonuclease VII, small subunit; InterPro IPR003761; KEGG: tde:TDE2066 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; IMG reference gene:2504920758; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; exodeoxyribonuclease 7 small subunit 2173974 10580370 Trebr_1843 Treponema brennaborense DSM 12168 exodeoxyribonuclease 7 small subunit YP_004440394.1 2173735 D 906968 CDS YP_004440395.1 332298473 10580371 2173971..2176016 1 NC_015500.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); HAMAP: DNA mismatch repair protein mutL; InterPro IPR014763:IPR003594:IPR013507:IPR014790; KEGG: tpp:TPASS_0303 DNA mismatch repair protein MutL; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATP-binding region, ATPase-like; SPTR: DNA mismatch repair protein; TIGRFAM: DNA mismatch repair protein, N-terminal; IMG reference gene:2504920759; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL; DNA mismatch repair protein mutL 2176016 10580371 Trebr_1844 Treponema brennaborense DSM 12168 DNA mismatch repair protein mutL YP_004440395.1 2173971 D 906968 CDS YP_004440396.1 332298474 10580372 complement(2176116..2178233) 1 NC_015500.1 InterPro IPR019734:IPR006597:IPR001440:IPR013105; KEGG: tde:TDE1127 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920760; PFAM: Tetratricopeptide repeat; hypothetical protein 2178233 10580372 Trebr_1845 Treponema brennaborense DSM 12168 hypothetical protein YP_004440396.1 2176116 R 906968 CDS YP_004440397.1 332298475 10580373 complement(2178208..2179044) 1 NC_015500.1 InterPro IPR019734:IPR013105:IPR001440; KEGG: tde:TDE1126 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920761; hypothetical protein 2179044 10580373 Trebr_1846 Treponema brennaborense DSM 12168 hypothetical protein YP_004440397.1 2178208 R 906968 CDS YP_004440398.1 332298476 10580374 2179177..2180544 1 NC_015500.1 InterPro IPR019734:IPR013105:IPR001440:IPR007560; KEGG: ssm:Spirs_2364 restriction endonuclease; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; Restriction endonuclease, type IV-like, Mrr; SPTR: Restriction endonuclease; IMG reference gene:2504920762; PFAM: Restriction endonuclease; hypothetical protein 2180544 10580374 Trebr_1847 Treponema brennaborense DSM 12168 hypothetical protein YP_004440398.1 2179177 D 906968 CDS YP_004440399.1 332298477 10580375 2180546..2181256 1 NC_015500.1 InterPro IPR004843; KEGG: sta:STHERM_c06590 Ser/Thr protein phosphatase family protein; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504920763; metallophosphoesterase 2181256 10580375 Trebr_1848 Treponema brennaborense DSM 12168 metallophosphoesterase YP_004440399.1 2180546 D 906968 CDS YP_004440400.1 332298478 10580376 2181253..2182158 1 NC_015500.1 KEGG: ssm:Spirs_2366 hypothetical protein; SPTR: Transcriptional regulator; IMG reference gene:2504920764; hypothetical protein 2182158 10580376 Trebr_1849 Treponema brennaborense DSM 12168 hypothetical protein YP_004440400.1 2181253 D 906968 CDS YP_004440401.1 332298479 10580377 2182224..2183879 1 NC_015500.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003018:IPR001932:IPR010822; KEGG: tde:TDE1123 sigma factor regulatory protein, PFAM: Sporulation stage II, protein E C-terminal; GAF; SMART: Protein phosphatase 2C-related; GAF; SPTR: sigma factor regulatory protein; IMG reference gene:2504920765; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase with GAF(s) sensor(s) 2183879 10580377 Trebr_1850 Treponema brennaborense DSM 12168 protein serine/threonine phosphatase with GAF(s) sensor(s) YP_004440401.1 2182224 D 906968 CDS YP_004440402.1 332298480 10580378 2183894..2184232 1 NC_015500.1 COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: tde:TDE1122 anti-anti-sigma factor; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist; IMG reference gene:2504920766; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 2184232 10580378 Trebr_1851 Treponema brennaborense DSM 12168 anti-sigma-factor antagonist YP_004440402.1 2183894 D 906968 CDS YP_004440403.1 332298481 10580379 2184266..2184817 1 NC_015500.1 KEGG: tde:TDE1121 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920767; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein 2184817 10580379 Trebr_1852 Treponema brennaborense DSM 12168 hypothetical protein YP_004440403.1 2184266 D 906968 CDS YP_004440404.1 332298482 10580380 complement(2184910..2185131) 1 NC_015500.1 COGs: COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); HAMAP: Carbon storage regulator; InterPro IPR003751; KEGG: ssm:Spirs_2607 carbon storage regulator, CsrA; PFAM: Carbon storage regulator; SPTR: Carbon storage regulator homolog; TIGRFAM: Carbon storage regulator; IMG reference gene:2504920768; PFAM: Global regulator protein family; TIGRFAM: carbon storage regulator (csrA); carbon storage regulator CsrA 2185131 10580380 Trebr_1853 Treponema brennaborense DSM 12168 carbon storage regulator CsrA YP_004440404.1 2184910 R 906968 CDS YP_004440405.1 332298483 10580381 complement(2185125..2185571) 1 NC_015500.1 COGs: COG1699 conserved hypothetical protein; HAMAP: Flagellar assembly factor FliW; InterPro IPR003775; KEGG: tde:TDE2354 flagellar assembly protein FliW; PFAM: Flagellar assembly factor FliW; SPTR: Flagellar assembly factor fliW; IMG reference gene:2504920769; PFAM: FliW protein; Flagellar assembly factor fliW 2185571 10580381 Trebr_1854 Treponema brennaborense DSM 12168 Flagellar assembly factor fliW YP_004440405.1 2185125 R 906968 CDS YP_004440406.1 332298484 10580382 complement(2185580..2186824) 1 NC_015500.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492:IPR010810; KEGG: tde:TDE2353 flagellar hook-associated protein FlgL; PFAM: Flagellin, N-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3; IMG reference gene:2504920770; PFAM: Bacterial flagellin N-terminal helical region; Flagellin hook IN motif; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3; flagellar hook-associated protein 3 2186824 10580382 Trebr_1855 Treponema brennaborense DSM 12168 flagellar hook-associated protein 3 YP_004440406.1 2185580 R 906968 CDS YP_004440407.1 332298485 10580383 complement(2186849..2188738) 1 NC_015500.1 COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR010810:IPR010930; KEGG: tde:TDE2352 flagellar hook-associated protein FlgK; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; IMG reference gene:2504920771; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; flagellar hook-associated protein FlgK 2188738 10580383 Trebr_1856 Treponema brennaborense DSM 12168 flagellar hook-associated protein FlgK YP_004440407.1 2186849 R 906968 CDS YP_004440408.1 332298486 10580384 complement(2188748..2189248) 1 NC_015500.1 KEGG: tde:TDE2351 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920772; PFAM: FlgN protein; hypothetical protein 2189248 10580384 Trebr_1857 Treponema brennaborense DSM 12168 hypothetical protein YP_004440408.1 2188748 R 906968 CDS YP_004440409.1 332298487 10580385 2189663..2191990 1 NC_015500.1 COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006416:IPR001757:IPR006121:IPR 008250:IPR005834; KEGG: cpy:Cphy_3877 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504920773; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase 2191990 10580385 Trebr_1858 Treponema brennaborense DSM 12168 heavy metal translocating P-type ATPase YP_004440409.1 2189663 D 906968 CDS YP_004440410.1 332298488 10580386 2192007..2192324 1 NC_015500.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: ere:EUBREC_0613 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Uncharacterized protein conserved in bacteria; IMG reference gene:2504920774; PFAM: Uncharacterised BCR, COG1937; hypothetical protein 2192324 10580386 Trebr_1859 Treponema brennaborense DSM 12168 hypothetical protein YP_004440410.1 2192007 D 906968 CDS YP_004440411.1 332298489 10580387 2192383..2192580 1 NC_015500.1 InterPro IPR006121; PFAM: Heavy metal transport/detoxification protein; SPTR: uncharacterized protein; IMG reference gene:2504920775; PFAM: Heavy-metal-associated domain; heavy metal transport/detoxification protein 2192580 10580387 Trebr_1860 Treponema brennaborense DSM 12168 heavy metal transport/detoxification protein YP_004440411.1 2192383 D 906968 CDS YP_004440412.1 332298490 10580388 complement(2192698..2193768) 1 NC_015500.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; HAMAP: N-acetyl-gamma-glutamyl-phosphate reductase; InterPro IPR000706:IPR000534:IPR012280; KEGG: clj:CLJU_c21540 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, NAD-binding; Semialdehyde dehydrogenase, dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; IMG reference gene:2504920776; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form; N-acetyl-gamma-glutamyl-phosphate reductase 2193768 10580388 Trebr_1861 Treponema brennaborense DSM 12168 N-acetyl-gamma-glutamyl-phosphate reductase YP_004440412.1 2192698 R 906968 CDS YP_004440413.1 332298491 10580389 complement(2193922..2196705) 1 NC_015500.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: sli:Slin_0550 histidine kinase; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Histidine kinase; IMG reference gene:2504920777; PFAM: 7TM diverse intracellular signalling; Response regulator receiver domain; Bacterial regulatory proteins, luxR family; two component transcriptional regulator, LuxR family 2196705 10580389 Trebr_1862 Treponema brennaborense DSM 12168 two component transcriptional regulator, LuxR family YP_004440413.1 2193922 R 906968 CDS YP_004440414.1 332298492 10580390 complement(2196717..2196860) 1 NC_015500.1 IMG reference gene:2504920778; hypothetical protein 2196860 10580390 Trebr_1863 Treponema brennaborense DSM 12168 hypothetical protein YP_004440414.1 2196717 R 906968 CDS YP_004440415.1 332298493 10580391 complement(2197081..2198265) 1 NC_015500.1 InterPro IPR002791; KEGG: cai:Caci_2189 protein of unknown function DUF89; PFAM: Domain of unknown function DUF89; SPTR: uncharacterized protein; IMG reference gene:2504920779; PFAM: Protein of unknown function DUF89; hypothetical protein 2198265 10580391 Trebr_1864 Treponema brennaborense DSM 12168 hypothetical protein YP_004440415.1 2197081 R 906968 CDS YP_004440416.1 332298494 10580392 2198479..2199702 1 NC_015500.1 KEGG: tde:TDE0194 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920780; hypothetical protein 2199702 10580392 Trebr_1865 Treponema brennaborense DSM 12168 hypothetical protein YP_004440416.1 2198479 D 906968 CDS YP_004440417.1 332298495 10580393 complement(2199798..2200274) 1 NC_015500.1 InterPro IPR019734; KEGG: tpp:TPASS_0625 hypothetical protein; SPTR: Tetratricopeptide repeat domain protein; manually curated; IMG reference gene:2504920781; hypothetical protein 2200274 10580393 Trebr_1866 Treponema brennaborense DSM 12168 hypothetical protein YP_004440417.1 2199798 R 906968 CDS YP_004440418.1 332298496 10580394 complement(2200384..2200704) 1 NC_015500.1 InterPro IPR001387; KEGG: bpu:BPUM_0550 transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Possible transcriptional regulator; IMG reference gene:2504920782; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2200704 10580394 Trebr_1867 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440418.1 2200384 R 906968 CDS YP_004440419.1 332298497 10580395 complement(2201089..2201436) 1 NC_015500.1 InterPro IPR001387; KEGG: cdf:CD2041 regulatory protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: uncharacterized protein; IMG reference gene:2504920783; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2201436 10580395 Trebr_1868 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440419.1 2201089 R 906968 CDS YP_004440420.1 332298498 10580396 2201535..2202260 1 NC_015500.1 IMG reference gene:2504920784; hypothetical protein 2202260 10580396 Trebr_1869 Treponema brennaborense DSM 12168 hypothetical protein YP_004440420.1 2201535 D 906968 CDS YP_004440421.1 332298499 10580398 2203376..2204212 1 NC_015500.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: coc:Coch_0693 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504920786; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2204212 10580398 Trebr_1871 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440421.1 2203376 D 906968 CDS YP_004440422.1 332298500 10580399 2204212..2205198 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: pgn:PGN_0225 probable glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Probable glycosyltransferase; IMG reference gene:2504920787; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2205198 10580399 Trebr_1872 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440422.1 2204212 D 906968 CDS YP_004440423.1 332298501 10580400 2205199..2206737 1 NC_015500.1 InterPro IPR002797; KEGG: dfe:Dfer_0062 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; manually curated; IMG reference gene:2504920788; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 2206737 10580400 Trebr_1873 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004440423.1 2205199 D 906968 CDS YP_004440424.1 332298502 10580401 2206741..2207694 1 NC_015500.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: tme:Tmel_1068 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Predicted glycosyltransferases; IMG reference gene:2504920789; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2207694 10580401 Trebr_1874 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440424.1 2206741 D 906968 CDS YP_004440425.1 332298503 10580402 2207691..2208548 1 NC_015500.1 InterPro IPR001173; KEGG: ppm:PPSC2_c4906 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504920790; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2208548 10580402 Trebr_1875 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440425.1 2207691 D 906968 CDS YP_004440426.1 332298504 10580403 2208548..2209738 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bad:BAD_1387 spore coat protein; PFAM: Glycosyl transferase, group 1; SPTR: uncharacterized protein; IMG reference gene:2504920791; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2209738 10580403 Trebr_1876 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440426.1 2208548 D 906968 CDS YP_004440427.1 332298505 10580404 2209735..2210469 1 NC_015500.1 COGs: COG3306 Glycosyltransferase involved in LPS biosynthesis; InterPro IPR002654; KEGG: bth:BT_1649 hypothetical protein; PFAM: Glycosyl transferase, family 25; SPTR: Glycoside transferase family 25; IMG reference gene:2504920792; PFAM: Glycosyltransferase family 25 (LPS biosynthesis protein); glycosyl transferase family protein 2210469 10580404 Trebr_1877 Treponema brennaborense DSM 12168 glycosyl transferase family protein YP_004440427.1 2209735 D 906968 CDS YP_004440428.1 332298506 10580405 2210469..2211605 1 NC_015500.1 KEGG: bfr:BF1440 capsular polysaccharide polymerase; SPTR: Capsular polysaccharide biosynthesis protein; IMG reference gene:2504920793; hypothetical protein 2211605 10580405 Trebr_1878 Treponema brennaborense DSM 12168 hypothetical protein YP_004440428.1 2210469 D 906968 CDS YP_004440429.1 332298507 10580406 2211627..2212733 1 NC_015500.1 KEGG: bth:BT_0478 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920794; hypothetical protein 2212733 10580406 Trebr_1879 Treponema brennaborense DSM 12168 hypothetical protein YP_004440429.1 2211627 D 906968 CDS YP_004440430.1 332298508 10580407 2213169..2214842 1 NC_015500.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di aminopimelateligase; InterPro IPR005761:IPR000713:IPR013221:IPR004101; KEGG: tde:TDE0825 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase, PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelateligase; IMG reference gene:2504920795; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase 2214842 10580407 Trebr_1880 Treponema brennaborense DSM 12168 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase YP_004440430.1 2213169 D 906968 CDS YP_004440431.1 332298509 10580408 2214839..2215960 1 NC_015500.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; HAMAP: D-alanine--D-alanine ligase; InterPro IPR005905:IPR011127:IPR011095; KEGG: tde:TDE2385 D-alanyl-alanine synthetase A; PFAM: D-alanine--D-alanine ligase, C-terminal; D-alanine--D-alanine ligase, N-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; IMG reference gene:2504920796; PFAM: D-ala D-ala ligase N-terminus; D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase; D-alanine--D-alanine ligase 2215960 10580408 Trebr_1881 Treponema brennaborense DSM 12168 D-alanine--D-alanine ligase YP_004440431.1 2214839 D 906968 CDS YP_004440432.1 332298510 10580409 2215964..2217499 1 NC_015500.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762:IPR013221:IPR004101; KEGG: tde:TDE0370 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; IMG reference gene:2504920797; PFAM: Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase 2217499 10580409 Trebr_1882 Treponema brennaborense DSM 12168 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004440432.1 2215964 D 906968 CDS YP_004440433.1 332298511 10580410 complement(2217538..2219460) 1 NC_015500.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tde:TDE2186 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: long-chain-fatty-acid--CoA ligase; IMG reference gene:2504920798; PFAM: AMP-binding enzyme; long-chain-fatty-acid--CoA ligase 2219460 10580410 Trebr_1883 Treponema brennaborense DSM 12168 long-chain-fatty-acid--CoA ligase YP_004440433.1 2217538 R 906968 CDS YP_004440434.1 332298512 10580411 complement(2219632..2220858) 1 NC_015500.1 COGs: COG0104 Adenylosuccinate synthase; HAMAP: Adenylosuccinate synthetase; InterPro IPR001114; KEGG: ssm:Spirs_2415 adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: Adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; TIGRFAM: Adenylosuccinate synthetase; IMG reference gene:2504920799; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase; adenylosuccinate synthetase 2220858 10580411 Trebr_1884 Treponema brennaborense DSM 12168 adenylosuccinate synthetase YP_004440434.1 2219632 R 906968 CDS YP_004440435.1 332298513 10580412 2221089..2221886 1 NC_015500.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR020013:IPR012836:IPR001444:IPR010930; KEGG: tde:TDE1006 flagellar basal-body rod protein FlgG; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504920800; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; flagellar basal-body rod protein FlgF 2221886 10580412 Trebr_1885 Treponema brennaborense DSM 12168 flagellar basal-body rod protein FlgF YP_004440435.1 2221089 D 906968 CDS YP_004440436.1 332298514 10580413 2221906..2222700 1 NC_015500.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR020013:IPR012834:IPR001444:IPR010930; KEGG: tde:TDE1007 flagellar basal body rod protein FlgG; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-body rod FlgG; Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504920801; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria; flagellar basal-body rod protein FlgG 2222700 10580413 Trebr_1886 Treponema brennaborense DSM 12168 flagellar basal-body rod protein FlgG YP_004440436.1 2221906 D 906968 CDS YP_004440437.1 332298515 10580414 2222725..2223303 1 NC_015500.1 InterPro IPR019301; KEGG: tde:TDE1008 flagellar protein, PFAM: Flagellar protein FlgJ, N-terminal; SPTR: flagellar protein; IMG reference gene:2504920802; PFAM: Rod binding protein; flagellar protein FlgJ 2223303 10580414 Trebr_1887 Treponema brennaborense DSM 12168 flagellar protein FlgJ YP_004440437.1 2222725 D 906968 CDS YP_004440438.1 332298516 10580415 2223493..2225574 1 NC_015500.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225:IPR000795:IPR004161:IPR005517:IPR 000640; KEGG: tde:TDE0947 translation elongation factor G, PFAM: Translation elongation factor EFG/EF2, domain IV; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: Translation elongation factor G, ; TIGRFAM: Small GTP-binding protein; IMG reference gene:2504920803; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; small GTP-binding protein 2225574 10580415 Trebr_1888 Treponema brennaborense DSM 12168 small GTP-binding protein YP_004440438.1 2223493 D 906968 CDS YP_004440439.1 332298517 10580416 complement(2225674..2226486) 1 NC_015500.1 COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Phosphomannose isomerase type I; IMG reference gene:2504920804; PFAM: Phosphomannose isomerase type I; Mannose-6-phosphate isomerase 2226486 10580416 Trebr_1889 Treponema brennaborense DSM 12168 Mannose-6-phosphate isomerase YP_004440439.1 2225674 R 906968 CDS YP_004440440.1 332298518 10580417 complement(2226490..2227398) 1 NC_015500.1 KEGG: tde:TDE0603 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920805; hypothetical protein 2227398 10580417 Trebr_1890 Treponema brennaborense DSM 12168 hypothetical protein YP_004440440.1 2226490 R 906968 CDS YP_004440441.1 332298519 10580418 complement(2227570..2228232) 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504920806; hypothetical protein 2228232 10580418 Trebr_1891 Treponema brennaborense DSM 12168 hypothetical protein YP_004440441.1 2227570 R 906968 CDS YP_004440442.1 332298520 10580419 complement(2228435..2229139) 1 NC_015500.1 COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; InterPro IPR004402:IPR000845; KEGG: cbk:CLL_A2969 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase deoD-type 2; TIGRFAM: Purine nucleoside phosphorylase; IMG reference gene:2504920807; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); purine nucleoside phosphorylase 2229139 10580419 Trebr_1892 Treponema brennaborense DSM 12168 purine nucleoside phosphorylase YP_004440442.1 2228435 R 906968 CDS YP_004440443.1 332298521 10580420 2229300..2229749 1 NC_015500.1 COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: cpy:Cphy_2940 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: membrane protein; IMG reference gene:2504920808; PFAM: NfeD-like; hypothetical protein 2229749 10580420 Trebr_1893 Treponema brennaborense DSM 12168 hypothetical protein YP_004440443.1 2229300 D 906968 CDS YP_004440444.1 332298522 10580421 2229938..2230822 1 NC_015500.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: ere:EUBREC_3261 membrane protease subunits, stomatin/prohibitin-like protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7/Mec-2 family protein; IMG reference gene:2504920809; PFAM: SPFH domain / Band 7 family; hypothetical protein 2230822 10580421 Trebr_1894 Treponema brennaborense DSM 12168 hypothetical protein YP_004440444.1 2229938 D 906968 CDS YP_004440445.1 332298523 10580422 complement(2230905..2231465) 1 NC_015500.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: tde:TDE1743 chromate transport protein; PFAM: Chromate transporter region; SPTR: Chromate transport protein; IMG reference gene:2504920810; PFAM: Chromate transporter; chromate transporter 2231465 10580422 Trebr_1895 Treponema brennaborense DSM 12168 chromate transporter YP_004440445.1 2230905 R 906968 CDS YP_004440446.1 332298524 10580423 complement(2231462..2232043) 1 NC_015500.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: tde:TDE1744 chromate transport protein; PFAM: Chromate transporter region; SPTR: Chromate transport protein; IMG reference gene:2504920811; PFAM: Chromate transporter; chromate transporter 2232043 10580423 Trebr_1896 Treponema brennaborense DSM 12168 chromate transporter YP_004440446.1 2231462 R 906968 CDS YP_004440447.1 332298525 10580424 2232134..2233471 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cpy:Cphy_3276 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504920812; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 2233471 10580424 Trebr_1897 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004440447.1 2232134 D 906968 CDS YP_004440448.1 332298526 10580425 2233558..2235042 1 NC_015500.1 COGs: COG0059 Ketol-acid reductoisomerase; HAMAP: Ketol-acid reductoisomerase; InterPro IPR013023:IPR013116:IPR000506; KEGG: chu:CHU_1149 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase C-terminal; Acetohydroxy acid isomeroreductase, catalytic; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: Acetohydroxy acid isomeroreductase; IMG reference gene:2504920813; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; ketol-acid reductoisomerase 2235042 10580425 Trebr_1898 Treponema brennaborense DSM 12168 ketol-acid reductoisomerase YP_004440448.1 2233558 D 906968 CDS YP_004440449.1 332298527 10580426 2235231..2235836 1 NC_015500.1 COGs: COG0560 Phosphoserine phosphatase; InterPro IPR011863:IPR005834; KEGG: bpb:bpr_I1141 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein ThrH; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: uncharacterized protein; TIGRFAM: Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; IMG reference gene:2504920814; TIGRFAM: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; bifunctional phosphoserine phosphatase/homoserine phosphotransferase 2235836 10580426 Trebr_1899 Treponema brennaborense DSM 12168 bifunctional phosphoserine phosphatase/homoserine phosphotransferase YP_004440449.1 2235231 D 906968 CDS YP_004440450.1 332298528 10580427 complement(2235833..2236603) 1 NC_015500.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ssm:Spirs_3150 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504920815; PFAM: ABC transporter; Fe(3+)-transporting ATPase 2236603 10580427 Trebr_1900 Treponema brennaborense DSM 12168 Fe(3+)-transporting ATPase YP_004440450.1 2235833 R 906968 CDS YP_004440451.1 332298529 10580428 complement(2236600..2237373) 1 NC_015500.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: slp:Slip_1021 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920816; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2237373 10580428 Trebr_1901 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440451.1 2236600 R 906968 CDS YP_004440452.1 332298530 10580429 complement(2237391..2238488) 1 NC_015500.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: ssm:Spirs_3152 NMT1/THI5 like domain protein; SPTR: NMT1/THI5 like domain protein; IMG reference gene:2504920817; PFAM: NMT1/THI5 like; NMT1/THI5 like domain-containing protein 2238488 10580429 Trebr_1902 Treponema brennaborense DSM 12168 NMT1/THI5 like domain-containing protein YP_004440452.1 2237391 R 906968 CDS YP_004440453.1 332298531 10580430 complement(2238669..2240054) 1 NC_015500.1 COGs: COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; InterPro IPR004839; KEGG: hch:HCH_01903 valine--pyruvate transaminase; PFAM: Aminotransferase, class I/II; PRIAM: Valine--pyruvate transaminase; SPTR: Alanine-alpha-ketoisovalerate/valine-pyruvate aminotransferase; IMG reference gene:2504920818; PFAM: Aminotransferase class I and II; Valine--pyruvate transaminase 2240054 10580430 Trebr_1903 Treponema brennaborense DSM 12168 Valine--pyruvate transaminase YP_004440453.1 2238669 R 906968 CDS YP_004440454.1 332298532 10580431 complement(2240051..2240464) 1 NC_015500.1 COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tde:TDE1707 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: uncharacterized protein; IMG reference gene:2504920819; PFAM: Protein of unknown function, DUF583; hypothetical protein 2240464 10580431 Trebr_1904 Treponema brennaborense DSM 12168 hypothetical protein YP_004440454.1 2240051 R 906968 CDS YP_004440455.1 332298533 10580432 complement(2240510..2241109) 1 NC_015500.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ssm:Spirs_3183 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein; IMG reference gene:2504920820; PFAM: Response regulator receiver domain; response regulator receiver protein 2241109 10580432 Trebr_1905 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004440455.1 2240510 R 906968 CDS YP_004440456.1 332298534 10580433 complement(2241078..2242775) 1 NC_015500.1 COGs: COG0815 Apolipoprotein N-acyltransferase; HAMAP: Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: sta:STHERM_c18560 hypothetical protein; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase; TIGRFAM: Apolipoprotein N-acyltransferase; IMG reference gene:2504920821; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 2242775 10580433 Trebr_1906 Treponema brennaborense DSM 12168 apolipoprotein N-acyltransferase YP_004440456.1 2241078 R 906968 CDS YP_004440457.1 332298535 10580434 complement(2242783..2243088) 1 NC_015500.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: sta:STHERM_c18570 DNA-binding protein HbbU; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein; IMG reference gene:2504920822; PFAM: Bacterial DNA-binding protein; histone family protein DNA-binding protein 2243088 10580434 Trebr_1907 Treponema brennaborense DSM 12168 histone family protein DNA-binding protein YP_004440457.1 2242783 R 906968 CDS YP_004440458.1 332298536 10580435 complement(2243180..2243467) 1 NC_015500.1 HAMAP: Ribosomal protein S20; InterPro IPR002583; KEGG: tde:TDE1710 30S ribosomal protein S20; PFAM: Ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: Ribosomal protein S20; manually curated; IMG reference gene:2504920823; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20; 30S ribosomal protein S20 2243467 10580435 Trebr_1908 Treponema brennaborense DSM 12168 30S ribosomal protein S20 YP_004440458.1 2243180 R 906968 CDS YP_004440459.1 332298537 10580436 complement(2243586..2244446) 1 NC_015500.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: tde:TDE2162 NOL1/NOP2/sun family protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: NOL1/NOP2/sun family protein; IMG reference gene:2504920824; PFAM: NOL1/NOP2/sun family; Fmu (Sun) domain-containing protein 2244446 10580436 Trebr_1909 Treponema brennaborense DSM 12168 Fmu (Sun) domain-containing protein YP_004440459.1 2243586 R 906968 CDS YP_004440460.1 332298538 10580437 complement(2244439..2245329) 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: tde:TDE2195 RNA pseudouridylate synthase family protein; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; IMG reference gene:2504920825; PFAM: RNA pseudouridylate synthase; pseudouridine synthase 2245329 10580437 Trebr_1910 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004440460.1 2244439 R 906968 CDS YP_004440461.1 332298539 10580438 complement(2245326..2246741) 1 NC_015500.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: tde:TDE1221 glycosy hydrolase family protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Glycosyl hydrolase, family 3; IMG reference gene:2504920826; PFAM: Glycosyl hydrolase family 3 N terminal domain; glycoside hydrolase family protein 2246741 10580438 Trebr_1911 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004440461.1 2245326 R 906968 CDS YP_004440462.1 332298540 10580439 complement(2246710..2248554) 1 NC_015500.1 COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: tde:TDE1019 dicarboxylate transporter, DctM subunit, PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: Dicarboxylate transporter; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; IMG reference gene:2504920827; PFAM: DctM-like transporters; Tripartite ATP-independent periplasmic transporters, DctQ component; TIGRFAM: TRAP transporter, DctM subunit; TRAP dicarboxylate transporter subunit DctM 2248554 10580439 Trebr_1912 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctM YP_004440462.1 2246710 R 906968 CDS YP_004440463.1 332298541 10580440 complement(2248554..2249618) 1 NC_015500.1 COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389; KEGG: tde:TDE1020 dicarboxylate transporter, periplasmic dicarboxylate-binding protein, PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Tp33 protein; IMG reference gene:2504920828; PFAM: Bacterial extracellular solute-binding protein, family 7; extracellular solute-binding protein 2249618 10580440 Trebr_1913 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440463.1 2248554 R 906968 CDS YP_004440464.1 332298542 10580441 complement(2249820..2250833) 1 NC_015500.1 COGs: COG5660 integral membrane protein; KEGG: tpp:TPASS_0956 hypothetical protein; SPTR: lipoprotein; IMG reference gene:2504920829; hypothetical protein 2250833 10580441 Trebr_1914 Treponema brennaborense DSM 12168 hypothetical protein YP_004440464.1 2249820 R 906968 CDS YP_004440465.1 332298543 10580442 2251049..2252221 1 NC_015500.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: sta:STHERM_c00940 glycosylase; PFAM: Glycosidase, PH1107-related; SPTR: glycosylase; IMG reference gene:2504920830; PFAM: Domain of unknown function (DUF377); glycosidase-like protein 2252221 10580442 Trebr_1915 Treponema brennaborense DSM 12168 glycosidase-like protein YP_004440465.1 2251049 D 906968 CDS YP_004440466.1 332298544 10580443 complement(2252275..2253531) 1 NC_015500.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; IMG reference gene:2504920831; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase 2253531 10580443 Trebr_1916 Treponema brennaborense DSM 12168 N-acylglucosamine 2-epimerase YP_004440466.1 2252275 R 906968 CDS YP_004440467.1 332298545 10580444 complement(2253552..2254544) 1 NC_015500.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: ppm:PPSC2_c5160 glycosidase like protein; PFAM: Glycosidase, PH1107-related; SPTR: uncharacterized protein; IMG reference gene:2504920832; PFAM: Domain of unknown function (DUF377); glycosidase-like protein 2254544 10580444 Trebr_1917 Treponema brennaborense DSM 12168 glycosidase-like protein YP_004440467.1 2253552 R 906968 CDS YP_004440468.1 332298546 10580445 complement(2254722..2256902) 1 NC_015500.1 COGs: COG3934 Endo-beta-mannanase; InterPro IPR001547:IPR015295; KEGG: tna:CTN_1345 beta-mannosidase; PFAM: Carbohydrate binding module 27; Glycoside hydrolase, family 5; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: Beta-1,4-mannanase; IMG reference gene:2504920833; PFAM: Carbohydrate binding module 27; Cellulase (glycosyl hydrolase family 5); mannan endo-1,4-beta-mannosidase 2256902 10580445 Trebr_1918 Treponema brennaborense DSM 12168 mannan endo-1,4-beta-mannosidase YP_004440468.1 2254722 R 906968 CDS YP_004440469.1 332298547 10580446 complement(2257043..2258080) 1 NC_015500.1 COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: sta:STHERM_c07100 endoglucanase; PFAM: Glycoside hydrolase, family 5; SPTR: Endoglucanase; IMG reference gene:2504920834; PFAM: Cellulase (glycosyl hydrolase family 5); glycoside hydrolase family protein 2258080 10580446 Trebr_1919 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004440469.1 2257043 R 906968 CDS YP_004440470.1 332298548 10580447 complement(2258126..2259022) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: jde:Jden_1757 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Sugar transport system permease protein; IMG reference gene:2504920835; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2259022 10580447 Trebr_1920 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440470.1 2258126 R 906968 CDS YP_004440471.1 332298549 10580448 complement(2259025..2259900) 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ppm:PPSC2_c5162 sugar ABC transporter, permease protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter, permease protein; IMG reference gene:2504920836; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2259900 10580448 Trebr_1921 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440471.1 2259025 R 906968 CDS YP_004440472.1 332298550 10580449 complement(2260040..2261365) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ppy:PPE_04651 ABC-type sugar transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: ABC-type sugar transport system, periplasmic component; IMG reference gene:2504920837; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2261365 10580449 Trebr_1922 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440472.1 2260040 R 906968 CDS YP_004440473.1 332298551 10580450 2261758..2262378 1 NC_015500.1 KEGG: sta:STHERM_c00910 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920838; hypothetical protein 2262378 10580450 Trebr_1923 Treponema brennaborense DSM 12168 hypothetical protein YP_004440473.1 2261758 D 906968 CDS YP_004440474.1 332298552 10580451 2262405..2263904 1 NC_015500.1 KEGG: swo:Swol_0141 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920839; hypothetical protein 2263904 10580451 Trebr_1924 Treponema brennaborense DSM 12168 hypothetical protein YP_004440474.1 2262405 D 906968 CDS YP_004440475.1 332298553 10580452 2263985..2265406 1 NC_015500.1 IMG reference gene:2504920840; hypothetical protein 2265406 10580452 Trebr_1925 Treponema brennaborense DSM 12168 hypothetical protein YP_004440475.1 2263985 D 906968 CDS YP_004440476.1 332298554 10580453 2265502..2266494 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: HTH-type transcriptional regulator CelR; IMG reference gene:2504920841; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 2266494 10580453 Trebr_1926 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004440476.1 2265502 D 906968 CDS YP_004440477.1 332298555 10580454 2266561..2266845 1 NC_015500.1 InterPro IPR013097; KEGG: pvi:Cvib_0748 stress responsive alpha-beta barrel domain-containing protein; PFAM: Stress responsive alpha-beta barrel; SPTR: Stress responsive alpha-beta barrel domain protein; IMG reference gene:2504920842; PFAM: Stress responsive A/B Barrel Domain; stress responsive alpha-beta barrel domain-containing protein 2266845 10580454 Trebr_1927 Treponema brennaborense DSM 12168 stress responsive alpha-beta barrel domain-containing protein YP_004440477.1 2266561 D 906968 CDS YP_004440478.1 332298556 10580455 complement(2267006..2268670) 1 NC_015500.1 COGs: COG0696 Phosphoglyceromutase; InterPro IPR005995:IPR011258:IPR006124; KEGG: ssm:Spirs_0213 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: BPG-independent PGAM, N-terminal; Metalloenzyme; PRIAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; TIGRFAM: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; IMG reference gene:2504920843; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; phosphoglycerate mutase 2268670 10580455 Trebr_1928 Treponema brennaborense DSM 12168 phosphoglycerate mutase YP_004440478.1 2267006 R 906968 CDS YP_004440479.1 332298557 10580456 complement(2268751..2269458) 1 NC_015500.1 IMG reference gene:2504920844; hypothetical protein 2269458 10580456 Trebr_1929 Treponema brennaborense DSM 12168 hypothetical protein YP_004440479.1 2268751 R 906968 CDS YP_004440480.1 332298558 10580457 complement(2269455..2270006) 1 NC_015500.1 IMG reference gene:2504920845; hypothetical protein 2270006 10580457 Trebr_1930 Treponema brennaborense DSM 12168 hypothetical protein YP_004440480.1 2269455 R 906968 CDS YP_004440481.1 332298559 10580458 complement(2270143..2270469) 1 NC_015500.1 KEGG: cts:Ctha_2655 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920846; hypothetical protein 2270469 10580458 Trebr_1931 Treponema brennaborense DSM 12168 hypothetical protein YP_004440481.1 2270143 R 906968 CDS YP_004440482.1 332298560 10580459 complement(2270480..2271850) 1 NC_015500.1 COGs: COG4452 Inner membrane protein involved in colicin E2 resistance; InterPro IPR010364; KEGG: bhy:BHWA1_01610 hypothetical protein; PFAM: Uncharacterised protein family, inner membrane CreD; SPTR: Inner membrane CreD family protein; IMG reference gene:2504920847; PFAM: Inner membrane protein CreD; Inner membrane CreD family protein 2271850 10580459 Trebr_1932 Treponema brennaborense DSM 12168 Inner membrane CreD family protein YP_004440482.1 2270480 R 906968 CDS YP_004440483.1 332298561 10580460 complement(2271935..2272627) 1 NC_015500.1 COGs: COG0670 Integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: dvl:Dvul_0772 hypothetical protein; PFAM: Uncharacterised protein family UPF0005; SPTR: Inner membrane protein YbhL; IMG reference gene:2504920848; PFAM: Uncharacterised protein family UPF0005; hypothetical protein 2272627 10580460 Trebr_1933 Treponema brennaborense DSM 12168 hypothetical protein YP_004440483.1 2271935 R 906968 CDS YP_004440484.1 332298562 10580461 2272728..2275652 1 NC_015500.1 COGs: COG0612 Zn-dependent peptidase; KEGG: gau:GAU_0129 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920849; hypothetical protein 2275652 10580461 Trebr_1934 Treponema brennaborense DSM 12168 hypothetical protein YP_004440484.1 2272728 D 906968 CDS YP_004440485.1 332298563 10580462 complement(2275631..2277514) 1 NC_015500.1 COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tde:TDE1315 hypothetical protein; PFAM: Protein of unknown function DUF115; SPTR: Conserved domain protein; IMG reference gene:2504920850; PFAM: Protein of unknown function DUF115; hypothetical protein 2277514 10580462 Trebr_1935 Treponema brennaborense DSM 12168 hypothetical protein YP_004440485.1 2275631 R 906968 CDS YP_004440486.1 332298564 10580463 complement(2277495..2279360) 1 NC_015500.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460; KEGG: tde:TDE1314 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA; SPTR: Penicillin-binding protein; IMG reference gene:2504920851; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; peptidoglycan glycosyltransferase 2279360 10580463 Trebr_1936 Treponema brennaborense DSM 12168 peptidoglycan glycosyltransferase YP_004440486.1 2277495 R 906968 CDS YP_004440487.1 332298565 10580464 complement(2279357..2279866) 1 NC_015500.1 InterPro IPR000223:IPR019759; KEGG: tde:TDE1313 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504920852; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; signal peptidase I 2279866 10580464 Trebr_1937 Treponema brennaborense DSM 12168 signal peptidase I YP_004440487.1 2279357 R 906968 CDS YP_004440488.1 332298566 10580465 2279914..2281116 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR002482:IPR018392:IPR016047; KEGG: tde:TDE2753 LysM/M23/M37 peptidase; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: LysM domain/M23/M37 peptidase domain protein; IMG reference gene:2504920853; PFAM: Peptidase family M23; LysM domain; peptidase M23 2281116 10580465 Trebr_1938 Treponema brennaborense DSM 12168 peptidase M23 YP_004440488.1 2279914 D 906968 CDS YP_004440489.1 332298567 10580467 2281371..2283620 1 NC_015500.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: tde:TDE2434 polysaccharide deacetylase family protein; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase family protein; IMG reference gene:2504920855; PFAM: Polysaccharide deacetylase; polysaccharide deacetylase 2283620 10580467 Trebr_1940 Treponema brennaborense DSM 12168 polysaccharide deacetylase YP_004440489.1 2281371 D 906968 CDS YP_004440490.1 332298568 10580468 complement(2283746..2284870) 1 NC_015500.1 COGs: COG0082 Chorismate synthase; InterPro IPR000453; KEGG: sta:STHERM_c05920 chorismate synthase; PFAM: Chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: Chorismate synthase; IMG reference gene:2504920856; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase; chorismate synthase 2284870 10580468 Trebr_1941 Treponema brennaborense DSM 12168 chorismate synthase YP_004440490.1 2283746 R 906968 CDS YP_004440491.1 332298569 10580469 complement(2284897..2286795) 1 NC_015500.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005844; KEGG: tde:TDE0864 phosphohexose mutase family protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; SPTR: Phosphohexose mutase family protein; IMG reference gene:2504920857; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 2286795 10580469 Trebr_1942 Treponema brennaborense DSM 12168 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_004440491.1 2284897 R 906968 CDS YP_004440492.1 332298570 10580471 2287089..2288507 1 NC_015500.1 KEGG: ssm:Spirs_0276 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920859; hypothetical protein 2288507 10580471 Trebr_1943 Treponema brennaborense DSM 12168 hypothetical protein YP_004440492.1 2287089 D 906968 CDS YP_004440493.1 332298571 10580472 2288497..2290089 1 NC_015500.1 COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR000914; KEGG: tde:TDE2049 solute-binding family 5 protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Bacterial extracellular solute-binding protein, family 5; IMG reference gene:2504920860; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; ABC transporter substrate-binding protein 2290089 10580472 Trebr_1944 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004440493.1 2288497 D 906968 CDS YP_004440494.1 332298572 10580473 2290131..2290784 1 NC_015500.1 COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: sta:STHERM_c18970 transcriptional regulatory protein; PFAM: Transcription factor CarD; SPTR: Transcriptional regulator, CarD family; IMG reference gene:2504920861; PFAM: CarD-like/TRCF domain; BadM/Rrf2 family transcriptional regulator 2290784 10580473 Trebr_1945 Treponema brennaborense DSM 12168 BadM/Rrf2 family transcriptional regulator YP_004440494.1 2290131 D 906968 CDS YP_004440495.1 332298573 10580474 2290768..2292006 1 NC_015500.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; HAMAP: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; InterPro IPR003526:IPR001228; KEGG: tpp:TPASS_0512 hypothetical protein; PFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: Bifunctional enzyme IspD/ispF; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; IMG reference gene:2504920862; PFAM: YgbB family; Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2292006 10580474 Trebr_1946 Treponema brennaborense DSM 12168 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004440495.1 2290768 D 906968 CDS YP_004440496.1 332298574 10580475 complement(2292085..2295936) 1 NC_015500.1 KEGG: ssm:Spirs_3200 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920863; hypothetical protein 2295936 10580475 Trebr_1947 Treponema brennaborense DSM 12168 hypothetical protein YP_004440496.1 2292085 R 906968 CDS YP_004440497.1 332298575 10580476 complement(2295988..2296659) 1 NC_015500.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: tde:TDE2294 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Phosphoglycolate phosphatase; IMG reference gene:2504920864; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; haloacid dehalogenase domain-containing protein hydrolase 2296659 10580476 Trebr_1948 Treponema brennaborense DSM 12168 haloacid dehalogenase domain-containing protein hydrolase YP_004440497.1 2295988 R 906968 CDS YP_004440498.1 332298576 10580477 complement(2296656..2297777) 1 NC_015500.1 KEGG: spn:SP_1772 cell wall surface anchor family protein; SPTR: Cell wall surface anchor family protein; IMG reference gene:2504920865; hypothetical protein 2297777 10580477 Trebr_1949 Treponema brennaborense DSM 12168 hypothetical protein YP_004440498.1 2296656 R 906968 CDS YP_004440499.1 332298577 10580478 complement(2297781..2298194) 1 NC_015500.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: ssm:Spirs_3203 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; IMG reference gene:2504920866; PFAM: Biopolymer transport protein ExbD/TolR; biopolymer transport protein ExbD/TolR 2298194 10580478 Trebr_1950 Treponema brennaborense DSM 12168 biopolymer transport protein ExbD/TolR YP_004440499.1 2297781 R 906968 CDS YP_004440500.1 332298578 10580479 complement(2298196..2298819) 1 NC_015500.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: ssm:Spirs_3204 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; IMG reference gene:2504920867; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel 2298819 10580479 Trebr_1951 Treponema brennaborense DSM 12168 MotA/TolQ/ExbB proton channel YP_004440500.1 2298196 R 906968 CDS YP_004440501.1 332298579 10580480 complement(2298837..2300522) 1 NC_015500.1 KEGG: ssm:Spirs_3205 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920868; hypothetical protein 2300522 10580480 Trebr_1952 Treponema brennaborense DSM 12168 hypothetical protein YP_004440501.1 2298837 R 906968 CDS YP_004440502.1 332298580 10580481 complement(2301012..2304152) 1 NC_015500.1 COGs: COG1729 conserved hypothetical protein; KEGG: ssm:Spirs_3206 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; IMG reference gene:2504920869; hypothetical protein 2304152 10580481 Trebr_1953 Treponema brennaborense DSM 12168 hypothetical protein YP_004440502.1 2301012 R 906968 CDS YP_004440503.1 332298581 10580482 complement(2304205..2305584) 1 NC_015500.1 KEGG: tpp:TPASS_0457 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920870; hypothetical protein 2305584 10580482 Trebr_1954 Treponema brennaborense DSM 12168 hypothetical protein YP_004440503.1 2304205 R 906968 CDS YP_004440504.1 332298582 10580483 complement(2305660..2310141) 1 NC_015500.1 COGs: COG3580 conserved hypothetical protein; InterPro IPR008275:IPR002731:IPR018709; KEGG: tde:TDE1695 CoA-substrate-specific enzyme activase domain-containing protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase domain protein; TIGRFAM: CoA enzyme activase; IMG reference gene:2504920871; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase; CoA-substrate-specific enzyme activase 2310141 10580483 Trebr_1955 Treponema brennaborense DSM 12168 CoA-substrate-specific enzyme activase YP_004440504.1 2305660 R 906968 CDS YP_004440505.1 332298583 10580484 complement(2310157..2310894) 1 NC_015500.1 IMG reference gene:2504920872; hypothetical protein 2310894 10580484 Trebr_1956 Treponema brennaborense DSM 12168 hypothetical protein YP_004440505.1 2310157 R 906968 CDS YP_004440506.1 332298584 10580485 complement(2310909..2312474) 1 NC_015500.1 KEGG: tet:TTHERM_00321740 Kinesin motor domain containing protein; SPTR: M protein repeat protein; manually curated; IMG reference gene:2504920873; hypothetical protein 2312474 10580485 Trebr_1957 Treponema brennaborense DSM 12168 hypothetical protein YP_004440506.1 2310909 R 906968 CDS YP_004440507.1 332298585 10580486 complement(2312453..2314144) 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR003660; KEGG: sta:STHERM_c01070 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylyl cyclase class-3/4/guanylyl cyclase; IMG reference gene:2504920874; PFAM: Adenylate and Guanylate cyclase catalytic domain; adenylate/guanylate cyclase with integral membrane sensor 2314144 10580486 Trebr_1958 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase with integral membrane sensor YP_004440507.1 2312453 R 906968 CDS YP_004440508.1 332298586 10580487 2314208..2315827 1 NC_015500.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: tde:TDE0342 integral membrane protein MviN; PFAM: Flagellin assembly, membrane protein MviN; SPTR: Integral membrane protein MviN; TIGRFAM: Flagellin assembly, membrane protein MviN; IMG reference gene:2504920875; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN; integral membrane protein MviN 2315827 10580487 Trebr_1959 Treponema brennaborense DSM 12168 integral membrane protein MviN YP_004440508.1 2314208 D 906968 CDS YP_004440509.1 332298587 10580488 2315970..2317118 1 NC_015500.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: bmq:BMQ_3917 Xaa-Pro dipeptidase; PFAM: Peptidase M24, structural domain; SPTR: Xaa-Pro dipeptidase; IMG reference gene:2504920876; PFAM: Metallopeptidase family M24; peptidase M24 2317118 10580488 Trebr_1960 Treponema brennaborense DSM 12168 peptidase M24 YP_004440509.1 2315970 D 906968 CDS YP_004440510.1 332298588 10580489 complement(2317293..2320256) 1 NC_015500.1 COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440; KEGG: tde:TDE0447 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504920877; PFAM: Tetratricopeptide repeat; hypothetical protein 2320256 10580489 Trebr_1961 Treponema brennaborense DSM 12168 hypothetical protein YP_004440510.1 2317293 R 906968 CDS YP_004440511.1 332298589 10580490 complement(2320327..2321844) 1 NC_015500.1 InterPro IPR003961; KEGG: tpp:TPASS_0263 hypothetical protein; PFAM: Fibronectin, type III; SPTR: Fibronectin type III domain protein; manually curated; IMG reference gene:2504920878; fibronectin type III domain-containing protein 2321844 10580490 Trebr_1962 Treponema brennaborense DSM 12168 fibronectin type III domain-containing protein YP_004440511.1 2320327 R 906968 CDS YP_004440512.1 332298590 10580491 2321843..2323870 1 NC_015500.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: UvrABC system protein C; InterPro IPR004791:IPR000305:IPR001943:IPR001162; KEGG: tde:TDE2478 excinuclease ABC, C subunit; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit; manually curated; IMG reference gene:2504920879; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit; UvrABC system protein C 2323870 10580491 Trebr_1963 Treponema brennaborense DSM 12168 UvrABC system protein C YP_004440512.1 2321843 D 906968 CDS YP_004440513.1 332298591 10580492 complement(2323849..2325147) 1 NC_015500.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dau:Daud_0936 peptidase M16 domain-containing protein; PFAM: Peptidase M16, N-terminal; Peptidase M16, C-terminal; PRIAM: processing peptidase; SPTR: Peptidase M16 domain protein; IMG reference gene:2504920880; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); processing peptidase 2325147 10580492 Trebr_1964 Treponema brennaborense DSM 12168 processing peptidase YP_004440513.1 2323849 R 906968 CDS YP_004440514.1 332298592 10580493 complement(2325151..2327250) 1 NC_015500.1 COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); HAMAP: Polyribonucleotide nucleotidyltransferase; InterProIPR012162:IPR004087:IPR001247:IPR015847:IPR 015848:IPR018111:IPR003029; KEGG: tde:TDE1041 polynucleotide phosphorylase/polyadenylase; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; K Homology, type 1, subgroup; Ribosomal protein S1, RNA binding domain; PRIAM: Polyribonucleotide nucleotidyltransferase; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: Polyribonucleotide nucleotidyltransferase; IMG reference gene:2504920881; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; Polyribonucleotide nucleotidyltransferase, RNA binding domain; 3' exoribonuclease family, domain 2; TIGRFAM: polyribonucleotide nucleotidyltransferase; Polyribonucleotide nucleotidyltransferase 2327250 10580493 Trebr_1965 Treponema brennaborense DSM 12168 Polyribonucleotide nucleotidyltransferase YP_004440514.1 2325151 R 906968 CDS YP_004440515.1 332298593 10580494 complement(2327385..2327654) 1 NC_015500.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR005290:IPR000589; KEGG: tde:TDE1040 30S ribosomal protein S15; PFAM: Ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: Ribosomal protein S15, bacterial-type; IMG reference gene:2504920882; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle; 30S ribosomal protein S15 2327654 10580494 Trebr_1966 Treponema brennaborense DSM 12168 30S ribosomal protein S15 YP_004440515.1 2327385 R 906968 CDS YP_004440516.1 332298594 10580495 complement(2327694..2328548) 1 NC_015500.1 COGs: COG0196 FAD synthase; InterPro IPR015864; KEGG: tde:TDE1039 riboflavin biosynthesis protein, PFAM: FAD synthetase; SPTR: Riboflavin biosynthesis protein, ; IMG reference gene:2504920883; PFAM: FAD synthetase; FAD synthetase 2328548 10580495 Trebr_1967 Treponema brennaborense DSM 12168 FAD synthetase YP_004440516.1 2327694 R 906968 CDS YP_004440517.1 332298595 10580496 complement(2328541..2329554) 1 NC_015500.1 COGs: COG0130 Pseudouridine synthase; HAMAP: tRNA pseudouridine synthase B; InterPro IPR014780:IPR002501; KEGG: tde:TDE1104 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II, TruB, N-terminal; SPTR: tRNA pseudouridine synthase B; TIGRFAM: Pseudouridine synthase II, TruB, N-terminal, bacterial-type; IMG reference gene:2504920884; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase; tRNA pseudouridine synthase B 2329554 10580496 Trebr_1968 Treponema brennaborense DSM 12168 tRNA pseudouridine synthase B YP_004440517.1 2328541 R 906968 CDS YP_004440518.1 332298596 10580497 complement(2329577..2329948) 1 NC_015500.1 COGs: COG0858 Ribosome-binding factor A; HAMAP: Ribosome-binding factor A; InterPro IPR000238; KEGG: tde:TDE1105 ribosome-binding factor A; PFAM: Ribosome-binding factor A; SPTR: Ribosome-binding factor A; TIGRFAM: Ribosome-binding factor A; IMG reference gene:2504920885; PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; Ribosome-binding factor A 2329948 10580497 Trebr_1969 Treponema brennaborense DSM 12168 Ribosome-binding factor A YP_004440518.1 2329577 R 906968 CDS YP_004440519.1 332298597 10580498 complement(2329957..2332770) 1 NC_015500.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR005225:IPR006847:IPR000795:IPR 004161; KEGG: tde:TDE1106 translation initiation factor IF-2; PFAM: Protein synthesis factor, GTP-binding; Translation initiation factor IF-2, N-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Translation initiation factor IF-2; TIGRFAM: Initiation factor 2; Small GTP-binding protein; IMG reference gene:2504920886; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2; translation initiation factor IF-2 2332770 10580498 Trebr_1970 Treponema brennaborense DSM 12168 translation initiation factor IF-2 YP_004440519.1 2329957 R 906968 CDS YP_004440520.1 332298598 10580499 complement(2332779..2334230) 1 NC_015500.1 COGs: COG0195 Transcription elongation factor; InterPro IPR010213:IPR013735:IPR003029; KEGG: ssm:Spirs_2027 transcription termination factor NusA; PFAM: Transcription factor NusA, N-terminal; Ribosomal protein S1, RNA binding domain; SPTR: Transcription termination factor NusA; TIGRFAM: Transcription termination factor NusA; IMG reference gene:2504920887; PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA; NusA antitermination factor 2334230 10580499 Trebr_1971 Treponema brennaborense DSM 12168 NusA antitermination factor YP_004440520.1 2332779 R 906968 CDS YP_004440521.1 332298599 10580500 complement(2334244..2334753) 1 NC_015500.1 HAMAP: Uncharacterised protein family UPF0090, bacteria; InterPro IPR020790:IPR003728; KEGG: tde:TDE1108 hypothetical protein; PFAM: Uncharacterised protein family UPF0090; SPTR: Ribosome maturation factor rimP; IMG reference gene:2504920888; PFAM: Uncharacterised BCR, YhbC family COG0779; Ribosome maturation factor rimP 2334753 10580500 Trebr_1972 Treponema brennaborense DSM 12168 Ribosome maturation factor rimP YP_004440521.1 2334244 R 906968 CDS YP_004440522.1 332298600 10580501 complement(2335043..2335717) 1 NC_015500.1 IMG reference gene:2504920889; hypothetical protein 2335717 10580501 Trebr_1973 Treponema brennaborense DSM 12168 hypothetical protein YP_004440522.1 2335043 R 906968 CDS YP_004440523.1 332298601 10580503 complement(2336351..2337628) 1 NC_015500.1 KEGG: elm:ELI_1913 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920891; hypothetical protein 2337628 10580503 Trebr_1975 Treponema brennaborense DSM 12168 hypothetical protein YP_004440523.1 2336351 R 906968 CDS YP_004440524.1 332298602 10580504 complement(2338374..2339273) 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504920892; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 2339273 10580504 Trebr_1976 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004440524.1 2338374 R 906968 CDS YP_004440525.1 332298603 10580506 complement(2340109..2341350) 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504920894; PFAM: Transposase, Mutator family; transposase mutator type 2341350 10580506 Trebr_1978 Treponema brennaborense DSM 12168 transposase mutator type YP_004440525.1 2340109 R 906968 CDS YP_004440526.1 332298604 10580507 complement(2341678..2342595) 1 NC_015500.1 InterPro IPR003646:IPR013247; KEGG: lbf:LBF_0444 lipoprotein; PFAM: SH3, type 3; SMART: Bacterial SH3-like region; IMG reference gene:2504920895; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 2342595 10580507 Trebr_1979 Treponema brennaborense DSM 12168 SH3 type 3 domain-containing protein YP_004440526.1 2341678 R 906968 CDS YP_004440527.1 332298605 10580508 complement(2342597..2345056) 1 NC_015500.1 InterPro IPR016047; KEGG: ssm:Spirs_1766 hypothetical protein; PFAM: Peptidase M23; SPTR: uncharacterized protein; IMG reference gene:2504920896; PFAM: Peptidase family M23; peptidase M23 2345056 10580508 Trebr_1980 Treponema brennaborense DSM 12168 peptidase M23 YP_004440527.1 2342597 R 906968 CDS YP_004440528.1 332298606 10580509 complement(2345414..2346106) 1 NC_015500.1 InterPro IPR013247; PFAM: SH3, type 3; IMG reference gene:2504920897; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 2346106 10580509 Trebr_1981 Treponema brennaborense DSM 12168 SH3 type 3 domain-containing protein YP_004440528.1 2345414 R 906968 CDS YP_004440529.1 332298607 10580510 complement(2346096..2349356) 1 NC_015500.1 KEGG: sta:STHERM_c20200 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920898; hypothetical protein 2349356 10580510 Trebr_1982 Treponema brennaborense DSM 12168 hypothetical protein YP_004440529.1 2346096 R 906968 CDS YP_004440530.1 332298608 10580511 complement(2349958..2351241) 1 NC_015500.1 InterPro IPR013247; PFAM: SH3, type 3; IMG reference gene:2504920899; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 2351241 10580511 Trebr_1983 Treponema brennaborense DSM 12168 SH3 type 3 domain-containing protein YP_004440530.1 2349958 R 906968 CDS YP_004440531.1 332298609 10580512 complement(2351247..2351570) 1 NC_015500.1 IMG reference gene:2504920900; hypothetical protein 2351570 10580512 Trebr_1984 Treponema brennaborense DSM 12168 hypothetical protein YP_004440531.1 2351247 R 906968 CDS YP_004440532.1 332298610 10580513 complement(2351752..2352675) 1 NC_015500.1 KEGG: ssm:Spirs_1767 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920901; hypothetical protein 2352675 10580513 Trebr_1985 Treponema brennaborense DSM 12168 hypothetical protein YP_004440532.1 2351752 R 906968 CDS YP_004440533.1 332298611 10580514 complement(2352706..2354028) 1 NC_015500.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: dvl:Dvul_0571 phenylacetate--CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate--CoA ligase; IMG reference gene:2504920902; PFAM: AMP-binding enzyme; phenylacetate--CoA ligase 2354028 10580514 Trebr_1986 Treponema brennaborense DSM 12168 phenylacetate--CoA ligase YP_004440533.1 2352706 R 906968 CDS YP_004440534.1 332298612 10580515 complement(2354087..2354653) 1 NC_015500.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: pdi:BDI_1799 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Indolepyruvate oxidoreductase subunit IorB; IMG reference gene:2504920903; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; Indolepyruvate ferredoxin oxidoreductase 2354653 10580515 Trebr_1987 Treponema brennaborense DSM 12168 Indolepyruvate ferredoxin oxidoreductase YP_004440534.1 2354087 R 906968 CDS YP_004440535.1 332298613 10580516 complement(2354670..2356409) 1 NC_015500.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR011766; KEGG: ssm:Spirs_3355 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding protein; IMG reference gene:2504920904; PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit; Indolepyruvate ferredoxin oxidoreductase 2356409 10580516 Trebr_1988 Treponema brennaborense DSM 12168 Indolepyruvate ferredoxin oxidoreductase YP_004440535.1 2354670 R 906968 CDS YP_004440536.1 332298614 10580517 2356632..2357804 1 NC_015500.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183; KEGG: tde:TDE1109 pyridoxal-dependent family decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; PRIAM: Ornithine decarboxylase; SPTR: Decarboxylase, pyridoxal-dependent family; IMG reference gene:2504920905; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; Ornithine decarboxylase 2357804 10580517 Trebr_1989 Treponema brennaborense DSM 12168 Ornithine decarboxylase YP_004440536.1 2356632 D 906968 CDS YP_004440537.1 332298615 10580518 complement(2357832..2358554) 1 NC_015500.1 COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR004402:IPR000845; KEGG: apv:Apar_0141 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase; PRIAM: Purine-nucleoside phosphorylase; SPTR: uncharacterized protein; TIGRFAM: Purine nucleoside phosphorylase; IMG reference gene:2504920906; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); purine nucleoside phosphorylase 2358554 10580518 Trebr_1990 Treponema brennaborense DSM 12168 purine nucleoside phosphorylase YP_004440537.1 2357832 R 906968 CDS YP_004440538.1 332298616 10580519 complement(2358564..2359109) 1 NC_015500.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: ols:Olsu_1303 YbaK/EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase associated region; SPTR: YbaK/ebsC protein; IMG reference gene:2504920907; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein; YbaK/prolyl-tRNA synthetase associated domain-containing protein 2359109 10580519 Trebr_1991 Treponema brennaborense DSM 12168 YbaK/prolyl-tRNA synthetase associated domain-containing protein YP_004440538.1 2358564 R 906968 CDS YP_004440539.1 332298617 10580520 complement(2359103..2360977) 1 NC_015500.1 IMG reference gene:2504920908; hypothetical protein 2360977 10580520 Trebr_1992 Treponema brennaborense DSM 12168 hypothetical protein YP_004440539.1 2359103 R 906968 CDS YP_004440540.1 332298618 10580521 complement(2360979..2362235) 1 NC_015500.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR002290:IPR017442; KEGG: hmg:100197403 similar to predicted protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; SPTR: Upstream serine/threonine kinase for the SNF1 complex; IMG reference gene:2504920909; PFAM: Protein kinase domain; serine/threonine protein kinase 2362235 10580521 Trebr_1993 Treponema brennaborense DSM 12168 serine/threonine protein kinase YP_004440540.1 2360979 R 906968 CDS YP_004440541.1 332298619 10580522 2362422..2362820 1 NC_015500.1 InterPro IPR001387; KEGG: fsu:Fisuc_2499 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504920910; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2362820 10580522 Trebr_1994 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440541.1 2362422 D 906968 CDS YP_004440542.1 332298620 10580523 2363027..2363743 1 NC_015500.1 KEGG: tde:TDE2734 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920911; hypothetical protein 2363743 10580523 Trebr_1995 Treponema brennaborense DSM 12168 hypothetical protein YP_004440542.1 2363027 D 906968 CDS YP_004440543.1 332298621 10580524 complement(2363928..2364929) 1 NC_015500.1 KEGG: tde:TDE0308 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920912; hypothetical protein 2364929 10580524 Trebr_1996 Treponema brennaborense DSM 12168 hypothetical protein YP_004440543.1 2363928 R 906968 CDS YP_004440544.1 332298622 10580525 complement(2364922..2365902) 1 NC_015500.1 KEGG: bbu:BBJ29 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920913; hypothetical protein 2365902 10580525 Trebr_1997 Treponema brennaborense DSM 12168 hypothetical protein YP_004440544.1 2364922 R 906968 CDS YP_004440545.1 332298623 10580527 complement(2366656..2367840) 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: bbu:BBJ27 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Efflux ABC transporter, permease protein; IMG reference gene:2504920915; PFAM: Predicted permease; hypothetical protein 2367840 10580527 Trebr_1999 Treponema brennaborense DSM 12168 hypothetical protein YP_004440545.1 2366656 R 906968 CDS YP_004440546.1 332298624 10580528 complement(2367837..2368505) 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: bpo:BP951000_0905 ABC transporter ATP-binding protein YbbA; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP binding protein, YbbA; IMG reference gene:2504920916; PFAM: ABC transporter; Phosphonate-transporting ATPase 2368505 10580528 Trebr_2000 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004440546.1 2367837 R 906968 CDS YP_004440547.1 332298625 10580529 complement(2368507..2369232) 1 NC_015500.1 KEGG: tde:TDE0307 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920917; hypothetical protein 2369232 10580529 Trebr_2001 Treponema brennaborense DSM 12168 hypothetical protein YP_004440547.1 2368507 R 906968 CDS YP_004440548.1 332298626 10580530 complement(2369204..2369965) 1 NC_015500.1 KEGG: bpo:BP951000_0908 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920918; hypothetical protein 2369965 10580530 Trebr_2002 Treponema brennaborense DSM 12168 hypothetical protein YP_004440548.1 2369204 R 906968 CDS YP_004440549.1 332298627 10580531 complement(2370500..2371102) 1 NC_015500.1 IMG reference gene:2504920919; hypothetical protein 2371102 10580531 Trebr_2003 Treponema brennaborense DSM 12168 hypothetical protein YP_004440549.1 2370500 R 906968 CDS YP_004440550.1 332298628 10580532 complement(2371180..2372817) 1 NC_015500.1 KEGG: gau:GAU_3908 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920920; PFAM: Peptidase M30; hypothetical protein 2372817 10580532 Trebr_2004 Treponema brennaborense DSM 12168 hypothetical protein YP_004440550.1 2371180 R 906968 CDS YP_004440551.1 332298629 10580533 complement(2372909..2373604) 1 NC_015500.1 IMG reference gene:2504920921; hypothetical protein 2373604 10580533 Trebr_2005 Treponema brennaborense DSM 12168 hypothetical protein YP_004440551.1 2372909 R 906968 CDS YP_004440552.1 332298630 10580534 complement(2373612..2374952) 1 NC_015500.1 IMG reference gene:2504920922; hypothetical protein 2374952 10580534 Trebr_2006 Treponema brennaborense DSM 12168 hypothetical protein YP_004440552.1 2373612 R 906968 CDS YP_004440553.1 332298631 10580535 complement(2374967..2375410) 1 NC_015500.1 IMG reference gene:2504920923; hypothetical protein 2375410 10580535 Trebr_2007 Treponema brennaborense DSM 12168 hypothetical protein YP_004440553.1 2374967 R 906968 CDS YP_004440554.1 332298632 10580536 complement(2375425..2375844) 1 NC_015500.1 IMG reference gene:2504920924; hypothetical protein 2375844 10580536 Trebr_2008 Treponema brennaborense DSM 12168 hypothetical protein YP_004440554.1 2375425 R 906968 CDS YP_004440555.1 332298633 10580537 complement(2375882..2376871) 1 NC_015500.1 IMG reference gene:2504920925; hypothetical protein 2376871 10580537 Trebr_2009 Treponema brennaborense DSM 12168 hypothetical protein YP_004440555.1 2375882 R 906968 CDS YP_004440556.1 332298634 10580538 2377096..2377878 1 NC_015500.1 KEGG: tde:TDE1939 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920926; hypothetical protein 2377878 10580538 Trebr_2010 Treponema brennaborense DSM 12168 hypothetical protein YP_004440556.1 2377096 D 906968 CDS YP_004440557.1 332298635 10580539 2378069..2379757 1 NC_015500.1 COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547:IPR002645; KEGG: fsu:Fisuc_0530 sulfate transporter; PFAM: Sulphate transporter; Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Sulfate permease; IMG reference gene:2504920927; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: high affinity sulphate transporter 1; sulfate transporter 2379757 10580539 Trebr_2011 Treponema brennaborense DSM 12168 sulfate transporter YP_004440557.1 2378069 D 906968 CDS YP_004440558.1 332298636 10580540 2379950..2381299 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ccb:Clocel_0513 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504920928; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2381299 10580540 Trebr_2012 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440558.1 2379950 D 906968 CDS YP_004440559.1 332298637 10580541 2381427..2382272 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ccb:Clocel_0514 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920929; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2382272 10580541 Trebr_2013 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440559.1 2381427 D 906968 CDS YP_004440560.1 332298638 10580542 2382269..2383123 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cst:CLOST_1213 maltose transport protein amyc; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Maltose transport protein AmyC; IMG reference gene:2504920930; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2383123 10580542 Trebr_2014 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440560.1 2382269 D 906968 CDS YP_004440561.1 332298639 10580543 2383268..2383699 1 NC_015500.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736:IPR006683; KEGG: bpb:bpr_III143 thioesterase family protein; PFAM: Thioesterase superfamily; SPTR: uncharacterized protein; TIGRFAM: Phenylacetic acid degradation-related protein; IMG reference gene:2504920931; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation-related protein 2383699 10580543 Trebr_2015 Treponema brennaborense DSM 12168 phenylacetic acid degradation-related protein YP_004440561.1 2383268 D 906968 CDS YP_004440562.1 332298640 10580544 2383821..2386400 1 NC_015500.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104; KEGG: sta:STHERM_c02500 beta-mannosidase precursor; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; PRIAM: Beta-mannosidase; SPTR: Beta-mannosidase; IMG reference gene:2504920932; PFAM: Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Beta-mannosidase 2386400 10580544 Trebr_2016 Treponema brennaborense DSM 12168 Beta-mannosidase YP_004440562.1 2383821 D 906968 CDS YP_004440563.1 332298641 10580545 complement(2386605..2387768) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_1200 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920933; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2387768 10580545 Trebr_2017 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440563.1 2386605 R 906968 CDS YP_004440564.1 332298642 10580546 complement(2387770..2388684) 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_1199 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504920934; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2388684 10580546 Trebr_2018 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440564.1 2387770 R 906968 CDS YP_004440565.1 332298643 10580547 complement(2388802..2390085) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ssm:Spirs_1198 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504920935; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2390085 10580547 Trebr_2019 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440565.1 2388802 R 906968 CDS YP_004440566.1 332298644 10580548 complement(2390261..2391610) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c02610 sugar ABC transporter sugar-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504920936; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2391610 10580548 Trebr_2020 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004440566.1 2390261 R 906968 CDS YP_004440567.1 332298645 10580549 complement(2391607..2392851) 1 NC_015500.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000835:IPR000600; KEGG: ssm:Spirs_1197 ROK family protein; PFAM: ROK; HTH transcriptional regulator, MarR; SPTR: Regulatory protein MarR; IMG reference gene:2504920937; PFAM: ROK family; MarR family; ROK family protein 2392851 10580549 Trebr_2021 Treponema brennaborense DSM 12168 ROK family protein YP_004440567.1 2391607 R 906968 CDS YP_004440568.1 332298646 10580550 complement(2393095..2393898) 1 NC_015500.1 COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; HAMAP: Glucosamine-6-phosphate deaminase; InterPro IPR018322:IPR006148; KEGG: bvu:BVU_4120 glucosamine-6-phosphate deaminase; PFAM: Glucosamine/galactosamine-6-phosphate isomerase; PRIAM: Glucosamine-6-phosphate deaminase; SPTR: Glucosamine-6-phosphate deaminase; TIGRFAM: Glucosamine-6-phosphate isomerase, subgroup; IMG reference gene:2504920938; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase; glucosamine-6-phosphate deaminase 2393898 10580550 Trebr_2022 Treponema brennaborense DSM 12168 glucosamine-6-phosphate deaminase YP_004440568.1 2393095 R 906968 CDS YP_004440569.1 332298647 10580551 complement(2394015..2395181) 1 NC_015500.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: ssm:Spirs_1362 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; IMG reference gene:2504920939; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 2395181 10580551 Trebr_2023 Treponema brennaborense DSM 12168 N-acetylglucosamine-6-phosphate deacetylase YP_004440569.1 2394015 R 906968 CDS YP_004440570.1 332298648 10580552 2395385..2397856 1 NC_015500.1 COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342:IPR010383:IPR010403; KEGG: cth:Cthe_0275 cellobiose phosphorylase; PFAM: Glycosyltransferase 36; carbohydrate binding; Glycosyltransferase 36 associated; SPTR: Glycosyltransferase 36; IMG reference gene:2504920940; PFAM: Glycosyltransferase family 36; carbohydrate binding domain; Glycosyltransferase 36 associated family; glycosyltransferase 2397856 10580552 Trebr_2024 Treponema brennaborense DSM 12168 glycosyltransferase YP_004440570.1 2395385 D 906968 CDS YP_004440571.1 332298649 10580553 2397952..2398836 1 NC_015500.1 IMG reference gene:2504920941; hypothetical protein 2398836 10580553 Trebr_2025 Treponema brennaborense DSM 12168 hypothetical protein YP_004440571.1 2397952 D 906968 CDS YP_004440572.1 332298650 10580554 complement(2398974..2399222) 1 NC_015500.1 KEGG: hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920942; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; hypothetical protein 2399222 10580554 Trebr_2026 Treponema brennaborense DSM 12168 hypothetical protein YP_004440572.1 2398974 R 906968 CDS YP_004440573.1 332298651 10580555 complement(2399236..2400432) 1 NC_015500.1 COGs: COG2985 permease; InterPro IPR006512; KEGG: toc:Toce_1835 YidE/YbjL duplication; PFAM: YidE/YbjL duplication; SPTR: Predicted permease; TIGRFAM: YidE/YbjL duplication; IMG reference gene:2504920943; PFAM: Predicted Permease Membrane Region; TIGRFAM: AspT/YidE/YbjL antiporter duplication domain; YidE/YbjL duplication 2400432 10580555 Trebr_2027 Treponema brennaborense DSM 12168 YidE/YbjL duplication YP_004440573.1 2399236 R 906968 CDS YP_004440574.1 332298652 10580556 complement(2400448..2402061) 1 NC_015500.1 COGs: COG0029 Aspartate oxidase; InterPro IPR003953; KEGG: ipo:Ilyop_2558 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; PRIAM: L-aspartate oxidase; SPTR: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; IMG reference gene:2504920944; PFAM: FAD binding domain; L-aspartate oxidase 2402061 10580556 Trebr_2028 Treponema brennaborense DSM 12168 L-aspartate oxidase YP_004440574.1 2400448 R 906968 CDS YP_004440575.1 332298653 10580557 complement(2402072..2402746) 1 NC_015500.1 InterPro IPR001041; KEGG: ipo:Ilyop_2559 ferredoxin; PFAM: Ferredoxin; SPTR: CO dehydrogenase/acetyl-CoA synthase alpha subunit; IMG reference gene:2504920945; PFAM: 2Fe-2S iron-sulfur cluster binding domain; ferredoxin 2402746 10580557 Trebr_2029 Treponema brennaborense DSM 12168 ferredoxin YP_004440575.1 2402072 R 906968 CDS YP_004440576.1 332298654 10580558 complement(2402759..2403586) 1 NC_015500.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333:IPR001433:IPR019480; KEGG: ipo:Ilyop_2560 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; IMG reference gene:2504920946; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; oxidoreductase FAD/NAD(P)-binding domain-containing protein 2403586 10580558 Trebr_2030 Treponema brennaborense DSM 12168 oxidoreductase FAD/NAD(P)-binding domain-containing protein YP_004440576.1 2402759 R 906968 CDS YP_004440577.1 332298655 10580559 complement(2403586..2404614) 1 NC_015500.1 KEGG: ipo:Ilyop_2561 4Fe-4S ferredoxin, iron-sulfur binding protein; SPTR: uncharacterized protein; IMG reference gene:2504920947; 4Fe-4S ferredoxin iron-sulfur binding protein 2404614 10580559 Trebr_2031 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding protein YP_004440577.1 2403586 R 906968 CDS YP_004440578.1 332298656 10580560 complement(2404614..2405540) 1 NC_015500.1 InterPro IPR001450; KEGG: mta:Moth_0814 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: uncharacterized protein; IMG reference gene:2504920948; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 2405540 10580560 Trebr_2032 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004440578.1 2404614 R 906968 CDS YP_004440579.1 332298657 10580561 complement(2405525..2405971) 1 NC_015500.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: ipo:Ilyop_2563 methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; SPTR: Hydrogenase, methyl-violgen-reducing type, delta subunit; IMG reference gene:2504920949; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; methyl-viologen-reducing hydrogenase delta subunit 2405971 10580561 Trebr_2033 Treponema brennaborense DSM 12168 methyl-viologen-reducing hydrogenase delta subunit YP_004440579.1 2405525 R 906968 CDS YP_004440580.1 332298658 10580562 complement(2405962..2407959) 1 NC_015500.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076:IPR001450; KEGG: ipo:Ilyop_2564 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Heterodisulfide reductase, subunit A and related polyferredoxins; IMG reference gene:2504920950; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase 2407959 10580562 Trebr_2034 Treponema brennaborense DSM 12168 FAD dependent oxidoreductase YP_004440580.1 2405962 R 906968 CDS YP_004440581.1 332298659 10580563 complement(2407981..2408373) 1 NC_015500.1 COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: ipo:Ilyop_2565 heterodisulfide reductase subunit C-like protein; SPTR: uncharacterized protein; IMG reference gene:2504920951; heterodisulfide reductase subunit C-like protein 2408373 10580563 Trebr_2035 Treponema brennaborense DSM 12168 heterodisulfide reductase subunit C-like protein YP_004440581.1 2407981 R 906968 CDS YP_004440582.1 332298660 10580564 complement(2408375..2409172) 1 NC_015500.1 COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: ipo:Ilyop_2566 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich region, CCG; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Heterodisulfide reductase, subunit B; IMG reference gene:2504920952; PFAM: Cysteine-rich domain; CoB--CoM heterodisulfide reductase 2409172 10580564 Trebr_2036 Treponema brennaborense DSM 12168 CoB--CoM heterodisulfide reductase YP_004440582.1 2408375 R 906968 CDS YP_004440583.1 332298661 10580565 complement(2409293..2410669) 1 NC_015500.1 COGs: COG0114 Fumarase; HAMAP: Fumarate hydratase class II; InterPro IPR005677:IPR000362:IPR018951; KEGG: afn:Acfer_2053 fumarate hydratase, class II; PFAM: Fumarate lyase; Fumarase C, C-terminal; PRIAM: Fumarate hydratase; SPTR: Fumarase; TIGRFAM: Fumarate hydratase, class II; IMG reference gene:2504920953; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: fumarate hydratase, class II; class II fumarate hydratase 2410669 10580565 Trebr_2037 Treponema brennaborense DSM 12168 class II fumarate hydratase YP_004440583.1 2409293 R 906968 CDS YP_004440584.1 332298662 10580566 complement(2410692..2411639) 1 NC_015500.1 COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: L-lactate dehydrogenase; InterPro IPR011304:IPR001236; KEGG: L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; PRIAM: L-lactate dehydrogenase; SPTR: L-lactate dehydrogenase; TIGRFAM: L-lactate dehydrogenase; IMG reference gene:2504920954; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase; L-lactate dehydrogenase 2411639 10580566 Trebr_2038 Treponema brennaborense DSM 12168 L-lactate dehydrogenase YP_004440584.1 2410692 R 906968 CDS YP_004440585.1 332298663 10580567 complement(2411845..2412669) 1 NC_015500.1 KEGG: bcl:ABC3712 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920955; hypothetical protein 2412669 10580567 Trebr_2039 Treponema brennaborense DSM 12168 hypothetical protein YP_004440585.1 2411845 R 906968 CDS YP_004440586.1 332298664 10580568 complement(2412666..2412950) 1 NC_015500.1 InterPro IPR001845; KEGG: bad:BAD_0895 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Toxin-antitoxin system, antitoxin component, ArsR family; IMG reference gene:2504920956; PFAM: Bacterial regulatory protein, arsR family; regulatory protein ArsR 2412950 10580568 Trebr_2040 Treponema brennaborense DSM 12168 regulatory protein ArsR YP_004440586.1 2412666 R 906968 CDS YP_004440587.1 332298665 10580569 2413075..2414499 1 NC_015500.1 KEGG: bpo:BP951000_2129 TPR domain-containing protein; SPTR: TPR domain-containing protein; IMG reference gene:2504920957; hypothetical protein 2414499 10580569 Trebr_2041 Treponema brennaborense DSM 12168 hypothetical protein YP_004440587.1 2413075 D 906968 CDS YP_004440588.1 332298666 10580570 complement(2414571..2415860) 1 NC_015500.1 COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043; KEGG: ssm:Spirs_3643 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil-xanthine permease; TIGRFAM: Xanthine/uracil permease; IMG reference gene:2504920958; PFAM: Permease family; TIGRFAM: uracil-xanthine permease; uracil-xanthine permease 2415860 10580570 Trebr_2042 Treponema brennaborense DSM 12168 uracil-xanthine permease YP_004440588.1 2414571 R 906968 CDS YP_004440589.1 332298667 10580571 2415980..2417038 1 NC_015500.1 COGs: COG3391 conserved hypothetical protein; KEGG: sta:STHERM_c03300 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920959; TIGRFAM: 40-residue YVTN family beta-propeller repeat; hypothetical protein 2417038 10580571 Trebr_2043 Treponema brennaborense DSM 12168 hypothetical protein YP_004440589.1 2415980 D 906968 CDS YP_004440590.1 332298668 10580572 complement(2417041..2419227) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: tde:TDE0640 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504920960; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2419227 10580572 Trebr_2044 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440590.1 2417041 R 906968 CDS YP_004440591.1 332298669 10580573 complement(2419464..2420561) 1 NC_015500.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; HAMAP: Isopropylmalate dehydrogenase; InterPro IPR004429:IPR001804; KEGG: cbt:CLH_0305 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: Isopropylmalate dehydrogenase; IMG reference gene:2504920961; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 2420561 10580573 Trebr_2045 Treponema brennaborense DSM 12168 3-isopropylmalate dehydrogenase YP_004440591.1 2419464 R 906968 CDS YP_004440592.1 332298670 10580574 2420877..2421203 1 NC_015500.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: csh:Closa_2423 transcriptional regulator, PadR-like family; PFAM: Transcriptional regulator PadR N-terminal-like; SPTR: Transcriptional regulator; IMG reference gene:2504920962; PFAM: Transcriptional regulator PadR-like family; PadR-like family transcriptional regulator 2421203 10580574 Trebr_2046 Treponema brennaborense DSM 12168 PadR-like family transcriptional regulator YP_004440592.1 2420877 D 906968 CDS YP_004440593.1 332298671 10580575 2421219..2421872 1 NC_015500.1 COGs: COG4709 membrane protein; InterPro IPR012963; KEGG: elm:ELI_0871 hypothetical protein; PFAM: Protein of unknown function DUF1700; SPTR: uncharacterized protein; IMG reference gene:2504920963; PFAM: Protein of unknown function (DUF1700); hypothetical protein 2421872 10580575 Trebr_2047 Treponema brennaborense DSM 12168 hypothetical protein YP_004440593.1 2421219 D 906968 CDS YP_004440594.1 332298672 10580576 2421869..2422732 1 NC_015500.1 KEGG: cpy:Cphy_1272 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920964; hypothetical protein 2422732 10580576 Trebr_2048 Treponema brennaborense DSM 12168 hypothetical protein YP_004440594.1 2421869 D 906968 CDS YP_004440595.1 332298673 10580577 2422760..2422984 1 NC_015500.1 COGs: COG1983 stress-responsive transcriptional regulator protein; InterPro IPR007168; KEGG: mba:Mbar_A0475 stress-responsive transcriptional regulator; PFAM: PspC; SPTR: stress-responsive transcriptional regulator; IMG reference gene:2504920965; PFAM: PspC domain; phage shock protein C, PspC 2422984 10580577 Trebr_2049 Treponema brennaborense DSM 12168 phage shock protein C, PspC YP_004440595.1 2422760 D 906968 CDS YP_004440596.1 332298674 10580578 complement(2423156..2423509) 1 NC_015500.1 InterPro IPR001387; KEGG: dae:Dtox_1519 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: uncharacterized protein; IMG reference gene:2504920966; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2423509 10580578 Trebr_2050 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440596.1 2423156 R 906968 CDS YP_004440597.1 332298675 10580579 2423655..2424380 1 NC_015500.1 IMG reference gene:2504920967; hypothetical protein 2424380 10580579 Trebr_2051 Treponema brennaborense DSM 12168 hypothetical protein YP_004440597.1 2423655 D 906968 CDS YP_004440598.1 332298676 10580580 2424478..2425902 1 NC_015500.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: cbt:CLH_3203 polysaccharide transporter; PFAM: Polysaccharide biosynthesis protein; SPTR: uncharacterized protein; IMG reference gene:2504920968; PFAM: Polysaccharide biosynthesis protein; polysaccharide biosynthesis protein 2425902 10580580 Trebr_2052 Treponema brennaborense DSM 12168 polysaccharide biosynthesis protein YP_004440598.1 2424478 D 906968 CDS YP_004440599.1 332298677 10580581 2425899..2426912 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cbt:CLH_3200 glycosyl transferase, group 2 family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family protein; IMG reference gene:2504920969; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2426912 10580581 Trebr_2053 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440599.1 2425899 D 906968 CDS YP_004440600.1 332298678 10580582 2426909..2428093 1 NC_015500.1 KEGG: amu:Amuc_2095 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920970; PFAM: Polysaccharide pyruvyl transferase; hypothetical protein 2428093 10580582 Trebr_2054 Treponema brennaborense DSM 12168 hypothetical protein YP_004440600.1 2426909 D 906968 CDS YP_004440601.1 332298679 10580583 2428083..2428868 1 NC_015500.1 COGs: COG3774 Mannosyltransferase OCH1; InterPro IPR007577; KEGG: lsl:LSL_0695 glycosyltransferase; PFAM: Glycosyltransferase sugar-binding region containing DXD motif; SPTR: Glycosyltransferase; IMG reference gene:2504920971; PFAM: Glycosyltransferase sugar-binding region containing DXD motif; glycosyltransferase family protein 2428868 10580583 Trebr_2055 Treponema brennaborense DSM 12168 glycosyltransferase family protein YP_004440601.1 2428083 D 906968 CDS YP_004440602.1 332298680 10580584 2428868..2429938 1 NC_015500.1 KEGG: sag:SAG1168 polysaccharide biosynthesis protein CpsH(V); SPTR: uncharacterized protein; IMG reference gene:2504920972; hypothetical protein 2429938 10580584 Trebr_2056 Treponema brennaborense DSM 12168 hypothetical protein YP_004440602.1 2428868 D 906968 CDS YP_004440603.1 332298681 10580585 2429925..2430734 1 NC_015500.1 InterPro IPR001173; KEGG: apr:Apre_0246 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: uncharacterized protein; IMG reference gene:2504920973; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2430734 10580585 Trebr_2057 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440603.1 2429925 D 906968 CDS YP_004440604.1 332298682 10580586 2430731..2431918 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bam:Bamb_0762 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; SPTR: WfaV; IMG reference gene:2504920974; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2431918 10580586 Trebr_2058 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440604.1 2430731 D 906968 CDS YP_004440605.1 332298683 10580587 complement(2432066..2432881) 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504920975; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 2432881 10580587 Trebr_2059 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004440605.1 2432066 R 906968 CDS YP_004440606.1 332298684 10580588 complement(2433320..2433544) 1 NC_015500.1 IMG reference gene:2504920976; hypothetical protein 2433544 10580588 Trebr_2060 Treponema brennaborense DSM 12168 hypothetical protein YP_004440606.1 2433320 R 906968 CDS YP_004440607.1 332298685 10580589 complement(2433754..2434122) 1 NC_015500.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: dhd:Dhaf_2962 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: uncharacterized protein; TIGRFAM: YjgF-like protein; IMG reference gene:2504920977; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; endoribonuclease L-PSP 2434122 10580589 Trebr_2061 Treponema brennaborense DSM 12168 endoribonuclease L-PSP YP_004440607.1 2433754 R 906968 CDS YP_004440608.1 332298686 10580590 2434186..2435100 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: mcl:MCCL_0332 hypothetical protein; PFAM: Carbohydrate/purine kinase; SPTR: Sugar kinases, ribokinase family; IMG reference gene:2504920978; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 2435100 10580590 Trebr_2062 Treponema brennaborense DSM 12168 PfkB domain-containing protein YP_004440608.1 2434186 D 906968 CDS YP_004440609.1 332298687 10580591 2435269..2436828 1 NC_015500.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR004527:IPR020058; KEGG: tde:TDE0204 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial; IMG reference gene:2504920979; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; glutamyl-tRNA synthetase 2436828 10580591 Trebr_2063 Treponema brennaborense DSM 12168 glutamyl-tRNA synthetase YP_004440609.1 2435269 D 906968 CDS YP_004440610.1 332298688 10580592 complement(2437009..2437923) 1 NC_015500.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: cpy:Cphy_3277 periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; IMG reference gene:2504920980; periplasmic binding protein/LacI transcriptional regulator 2437923 10580592 Trebr_2064 Treponema brennaborense DSM 12168 periplasmic binding protein/LacI transcriptional regulator YP_004440610.1 2437009 R 906968 CDS YP_004440611.1 332298689 10580593 complement(2437997..2438992) 1 NC_015500.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: csh:Closa_1913 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator; IMG reference gene:2504920981; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 2438992 10580593 Trebr_2065 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440611.1 2437997 R 906968 CDS YP_004440612.1 332298690 10580594 complement(2439028..2440536) 1 NC_015500.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: csh:Closa_1912 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504920982; PFAM: ABC transporter; monosaccharide-transporting ATPase 2440536 10580594 Trebr_2066 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004440612.1 2439028 R 906968 CDS YP_004440613.1 332298691 10580595 complement(2440547..2441806) 1 NC_015500.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: sli:Slin_6381 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; IMG reference gene:2504920983; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase 2441806 10580595 Trebr_2067 Treponema brennaborense DSM 12168 N-acylglucosamine 2-epimerase YP_004440613.1 2440547 R 906968 CDS YP_004440614.1 332298692 10580596 complement(2441877..2442890) 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: bae:BATR1942_03035 LacI family transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: uncharacterized protein; IMG reference gene:2504920984; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 2442890 10580596 Trebr_2068 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004440614.1 2441877 R 906968 CDS YP_004440615.1 332298693 10580598 complement(2443347..2445428) 1 NC_015500.1 COGs: COG2217 Cation transport ATPase; InterProIPR006404:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: str:Sterm_2557 cadmium-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: uncharacterized protein; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504920986; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; heavy metal translocating P-type ATPase 2445428 10580598 Trebr_2069 Treponema brennaborense DSM 12168 heavy metal translocating P-type ATPase YP_004440615.1 2443347 R 906968 CDS YP_004440616.1 332298694 10580599 complement(2445437..2445802) 1 NC_015500.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: elm:ELI_0446 hypothetical protein; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: uncharacterized protein; IMG reference gene:2504920987; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 2445802 10580599 Trebr_2070 Treponema brennaborense DSM 12168 ArsR family transcriptional regulator YP_004440616.1 2445437 R 906968 CDS YP_004440617.1 332298695 10580600 complement(2445969..2446649) 1 NC_015500.1 KEGG: tde:TDE1050 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920988; PFAM: KaiC; hypothetical protein 2446649 10580600 Trebr_2071 Treponema brennaborense DSM 12168 hypothetical protein YP_004440617.1 2445969 R 906968 CDS YP_004440618.1 332298696 10580601 complement(2446658..2448748) 1 NC_015500.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR004540:IPR005225:IPR000795:IPR004161:IPR 005517:IPR000640; KEGG: tde:TDE1049 elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 1; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; IMG reference gene:2504920989; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; translation elongation factor G 2448748 10580601 Trebr_2072 Treponema brennaborense DSM 12168 translation elongation factor G YP_004440618.1 2446658 R 906968 CDS YP_004440619.1 332298697 10580602 complement(2448849..2450306) 1 NC_015500.1 IMG reference gene:2504920990; hypothetical protein 2450306 10580602 Trebr_2073 Treponema brennaborense DSM 12168 hypothetical protein YP_004440619.1 2448849 R 906968 CDS YP_004440620.1 332298698 10580603 complement(2450358..2451188) 1 NC_015500.1 InterPro IPR007730; KEGG: tpa:TP0297 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; SPTR: Sporulation related repeat protein; IMG reference gene:2504920991; PFAM: Sporulation related domain; sporulation domain-containing protein 2451188 10580603 Trebr_2074 Treponema brennaborense DSM 12168 sporulation domain-containing protein YP_004440620.1 2450358 R 906968 CDS YP_004440621.1 332298699 10580604 complement(2451192..2451863) 1 NC_015500.1 COGs: COG0237 Dephospho-CoA kinase; HAMAP: Dephospho-CoA kinase; InterPro IPR001977; KEGG: tpp:TPASS_0296 hypothetical protein; SPTR: Dephospho-CoA kinase; TIGRFAM: Dephospho-CoA kinase; IMG reference gene:2504920992; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; dephospho-CoA kinase 2451863 10580604 Trebr_2075 Treponema brennaborense DSM 12168 dephospho-CoA kinase YP_004440621.1 2451192 R 906968 CDS YP_004440622.1 332298700 10580605 complement(2451863..2454643) 1 NC_015500.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR002421:IPR008918:IPR002562:IPR 001098:IPR020046:IPR020047; KEGG: tde:TDE1637 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2; 3'-5' exonuclease; DNA-directed DNA polymerase, family A, palm domain; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase 1; IMG reference gene:2504920993; PFAM: 3'-5' exonuclease; 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; DNA polymerase I 2454643 10580605 Trebr_2076 Treponema brennaborense DSM 12168 DNA polymerase I YP_004440622.1 2451863 R 906968 CDS YP_004440623.1 332298701 10580606 complement(2454731..2455654) 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504920994; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 2455654 10580606 Trebr_2077 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004440623.1 2454731 R 906968 CDS YP_004440624.1 332298702 10580607 complement(2456164..2457726) 1 NC_015500.1 SPTR: MspA protein; IMG reference gene:2504920995; hypothetical protein 2457726 10580607 Trebr_2078 Treponema brennaborense DSM 12168 hypothetical protein YP_004440624.1 2456164 R 906968 CDS YP_004440625.1 332298703 10580608 2457968..2458621 1 NC_015500.1 KEGG: tde:TDE1642 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504920996; hypothetical protein 2458621 10580608 Trebr_2079 Treponema brennaborense DSM 12168 hypothetical protein YP_004440625.1 2457968 D 906968 CDS YP_004440626.1 332298704 10580609 2458914..2460464 1 NC_015500.1 InterPro IPR005546; PFAM: Autotransporter beta-domain; SPTR: MspA protein; IMG reference gene:2504920997; PFAM: Autotransporter beta-domain; Autotransporter beta domain-containing protein 2460464 10580609 Trebr_2080 Treponema brennaborense DSM 12168 Autotransporter beta domain-containing protein YP_004440626.1 2458914 D 906968 CDS YP_004440627.1 332298705 10580610 2460896..2461735 1 NC_015500.1 InterPro IPR010106; KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504920998; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 2461735 10580610 Trebr_2081 Treponema brennaborense DSM 12168 hypothetical protein YP_004440627.1 2460896 D 906968 CDS YP_004440628.1 332298706 10580611 complement(2461743..2462846) 1 NC_015500.1 InterPro IPR002104; KEGG: ssm:Spirs_1738 hypothetical protein; PFAM: Integrase, catalytic core, phage; SPTR: uncharacterized protein; IMG reference gene:2504920999; PFAM: Phage integrase family; integrase family protein 2462846 10580611 Trebr_2082 Treponema brennaborense DSM 12168 integrase family protein YP_004440628.1 2461743 R 906968 CDS YP_004440629.1 332298707 10580612 2462988..2464322 1 NC_015500.1 COGs: COG0282 Acetate kinase; HAMAP: Acetate kinase; InterPro IPR004372:IPR000890; KEGG: tpp:TPASS_0476 acetate kinase; PFAM: Acetate/butyrate kinase; PRIAM: Acetate kinase; SPTR: Acetate kinase; TIGRFAM: Acetate kinase; IMG reference gene:2504921000; PFAM: Acetokinase family; TIGRFAM: acetate kinase; Acetate kinase 2464322 10580612 Trebr_2083 Treponema brennaborense DSM 12168 Acetate kinase YP_004440629.1 2462988 D 906968 CDS YP_004440630.1 332298708 10580613 2464343..2465491 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: nar:Saro_0151 PfkB; PFAM: Carbohydrate/purine kinase; SPTR: Sugar kinase, ribokinase family protein; IMG reference gene:2504921001; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 2465491 10580613 Trebr_2084 Treponema brennaborense DSM 12168 PfkB domain-containing protein YP_004440630.1 2464343 D 906968 CDS YP_004440631.1 332298709 10580614 complement(2465477..2466076) 1 NC_015500.1 COGs: COG0693 intracellular protease/amidase; InterPro IPR006287:IPR002818; KEGG: sta:STHERM_c18300 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: uncharacterized protein; TIGRFAM: DJ-1; IMG reference gene:2504921002; PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein; DJ-1 family protein 2466076 10580614 Trebr_2085 Treponema brennaborense DSM 12168 DJ-1 family protein YP_004440631.1 2465477 R 906968 CDS YP_004440632.1 332298710 10580615 2466159..2467400 1 NC_015500.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ssm:Spirs_4133 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein; IMG reference gene:2504921003; PFAM: Response regulator receiver domain; response regulator receiver protein 2467400 10580615 Trebr_2086 Treponema brennaborense DSM 12168 response regulator receiver protein YP_004440632.1 2466159 D 906968 CDS YP_004440633.1 332298711 10580616 2467419..2469503 1 NC_015500.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: ssm:Spirs_4132 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SPTR: Multi-sensor hybrid histidine kinase; IMG reference gene:2504921004; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; Hpt sensor hybrid histidine kinase 2469503 10580616 Trebr_2087 Treponema brennaborense DSM 12168 Hpt sensor hybrid histidine kinase YP_004440633.1 2467419 D 906968 CDS YP_004440634.1 332298712 10580617 2469500..2470369 1 NC_015500.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR004013; KEGG: sta:STHERM_c16830 histidinol-phosphatase; PFAM: PHP, C-terminal; SPTR: Probable histidinol-phosphatase; TIGRFAM: Histidinol phosphate phosphatase, HisJ; IMG reference gene:2504921005; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; HisJ family histidinol phosphate phosphatase 2470369 10580617 Trebr_2088 Treponema brennaborense DSM 12168 HisJ family histidinol phosphate phosphatase YP_004440634.1 2469500 D 906968 CDS YP_004440635.1 332298713 10580618 complement(2470415..2470771) 1 NC_015500.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR000962; KEGG: ssm:Spirs_0464 transcriptional regulator, TraR/DksA family; SPTR: Transcriptional regulator, TraR/DksA family; IMG reference gene:2504921006; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA; TraR/DksA family transcriptional regulator 2470771 10580618 Trebr_2089 Treponema brennaborense DSM 12168 TraR/DksA family transcriptional regulator YP_004440635.1 2470415 R 906968 CDS YP_004440636.1 332298714 10580619 2470880..2471098 1 NC_015500.1 COGs: COG0361 Translation initiation factor 1 (IF-1); HAMAP: Translation initiation factor IF-1; InterPro IPR004368:IPR006196; KEGG: tde:TDE2087 translation initiation factor IF-1; PFAM: S1, IF1 type; SPTR: Translation initiation factor IF-1; TIGRFAM: Translation initiation factor IF-1; IMG reference gene:2504921007; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1; Translation initiation factor IF-1 2471098 10580619 Trebr_2090 Treponema brennaborense DSM 12168 Translation initiation factor IF-1 YP_004440636.1 2470880 D 906968 CDS YP_004440637.1 332298715 10580620 complement(2471120..2471695) 1 NC_015500.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: pag:PLES_51451 chaperone protein DnaJ; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; IMG reference gene:2504921008; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 2471695 10580620 Trebr_2091 Treponema brennaborense DSM 12168 heat shock protein DnaJ domain-containing protein YP_004440637.1 2471120 R 906968 CDS YP_004440638.1 332298716 10580621 complement(2471757..2472428) 1 NC_015500.1 COGs: COG2840 conserved hypothetical protein; InterPro IPR002625; KEGG: tde:TDE1254 Smr domain-containing protein; PFAM: Smr protein/MutS2 C-terminal; SMART: Smr protein/MutS2 C-terminal; SPTR: Smr domain protein; IMG reference gene:2504921009; PFAM: Smr domain; Smr protein/MutS2 2472428 10580621 Trebr_2092 Treponema brennaborense DSM 12168 Smr protein/MutS2 YP_004440638.1 2471757 R 906968 CDS YP_004440639.1 332298717 10580622 complement(2472425..2473870) 1 NC_015500.1 SPTR: uncharacterized protein; IMG reference gene:2504921010; hypothetical protein 2473870 10580622 Trebr_2093 Treponema brennaborense DSM 12168 hypothetical protein YP_004440639.1 2472425 R 906968 CDS YP_004440640.1 332298718 10580623 complement(2473819..2475519) 1 NC_015500.1 InterPro IPR002035:IPR019734:IPR011717:IPR013105; KEGG: tde:TDE1251 BatB protein, PFAM: von Willebrand factor, type A; Tetratricopeptide TPR-4; Tetratricopeptide TPR2; SMART: von Willebrand factor, type A; Tetratricopeptide repeat; SPTR: BatB protein; IMG reference gene:2504921011; PFAM: von Willebrand factor type A domain; Tetratricopeptide repeat; von Willebrand factor type A 2475519 10580623 Trebr_2094 Treponema brennaborense DSM 12168 von Willebrand factor type A YP_004440640.1 2473819 R 906968 CDS YP_004440641.1 332298719 10580624 complement(2475516..2476517) 1 NC_015500.1 InterPro IPR002035; KEGG: tde:TDE1250 BatA protein, PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: BatA protein, ; IMG reference gene:2504921012; PFAM: von Willebrand factor type A domain; von Willebrand factor type A 2476517 10580624 Trebr_2095 Treponema brennaborense DSM 12168 von Willebrand factor type A YP_004440641.1 2475516 R 906968 CDS YP_004440642.1 332298720 10580625 complement(2476517..2477503) 1 NC_015500.1 KEGG: tde:TDE1249 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921013; hypothetical protein 2477503 10580625 Trebr_2096 Treponema brennaborense DSM 12168 hypothetical protein YP_004440642.1 2476517 R 906968 CDS YP_004440643.1 332298721 10580626 complement(2477505..2478407) 1 NC_015500.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: tde:TDE1248 hypothetical protein; PFAM: Protein of unknown function DUF58; SPTR: uncharacterized protein; IMG reference gene:2504921014; PFAM: Protein of unknown function DUF58; hypothetical protein 2478407 10580626 Trebr_2097 Treponema brennaborense DSM 12168 hypothetical protein YP_004440643.1 2477505 R 906968 CDS YP_004440644.1 332298722 10580627 complement(2478409..2479461) 1 NC_015500.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011703; KEGG: tde:TDE0319 hypothetical protein; PFAM: ATPase associated with various cellular activities, AAA-3; SPTR: uncharacterized protein; IMG reference gene:2504921015; PFAM: ATPase family associated with various cellular activities (AAA); ATPase 2479461 10580627 Trebr_2098 Treponema brennaborense DSM 12168 ATPase YP_004440644.1 2478409 R 906968 CDS YP_004440645.1 332298723 10580628 2479574..2480884 1 NC_015500.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ssm:Spirs_1023 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase class I and II; IMG reference gene:2504921016; PFAM: Aminotransferase class I and II; class I and II aminotransferase 2480884 10580628 Trebr_2099 Treponema brennaborense DSM 12168 class I and II aminotransferase YP_004440645.1 2479574 D 906968 CDS YP_004440646.1 332298724 10580629 2480865..2482169 1 NC_015500.1 KEGG: tde:TDE2185 lipoprotein; SPTR: Lipoprotein, ; IMG reference gene:2504921017; PFAM: Bacterial extracellular solute-binding protein; lipoprotein 2482169 10580629 Trebr_2100 Treponema brennaborense DSM 12168 lipoprotein YP_004440646.1 2480865 D 906968 CDS YP_004440647.1 332298725 10580630 2482223..2482615 1 NC_015500.1 KEGG: tde:TDE1987 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921018; hypothetical protein 2482615 10580630 Trebr_2101 Treponema brennaborense DSM 12168 hypothetical protein YP_004440647.1 2482223 D 906968 CDS YP_004440648.1 332298726 10580631 2482830..2484656 1 NC_015500.1 COGs: COG1274 Phosphoenolpyruvate carboxykinase (GTP); HAMAP: Phosphoenolpyruvate carboxykinase, GTP-utilising; InterPro IPR008209; KEGG: tpp:TPASS_0122 phosphoenolpyruvate carboxykinase; PFAM: Phosphoenolpyruvate carboxykinase, GTP-utilising; PRIAM: Phosphoenolpyruvate carboxykinase (GTP); SPTR: Phosphoenolpyruvate carboxykinase [GTP]; IMG reference gene:2504921019; PFAM: Phosphoenolpyruvate carboxykinase; Phosphoenolpyruvate carboxykinase (GTP) 2484656 10580631 Trebr_2102 Treponema brennaborense DSM 12168 Phosphoenolpyruvate carboxykinase (GTP) YP_004440648.1 2482830 D 906968 CDS YP_004440649.1 332298727 10580632 2484807..2485019 1 NC_015500.1 InterPro IPR007419; PFAM: BFD-like [2Fe-2S]-binding region; SPTR: BFD-like [2Fe-2S] binding domain; IMG reference gene:2504921020; PFAM: BFD-like [2Fe-2S] binding domain; BFD (2Fe-2S)-binding domain-containing protein 2485019 10580632 Trebr_2103 Treponema brennaborense DSM 12168 BFD (2Fe-2S)-binding domain-containing protein YP_004440649.1 2484807 D 906968 CDS YP_004440650.1 332298728 10580633 2485033..2485896 1 NC_015500.1 COGs: COG3868 conserved hypothetical protein; InterPro IPR004352; KEGG: ols:Olsu_0819 hypothetical protein; PFAM: TM1410 hypothetical-related protein; SPTR: uncharacterized protein; IMG reference gene:2504921021; PFAM: TM1410 hypothetical-related protein; hypothetical-like protein 2485896 10580633 Trebr_2104 Treponema brennaborense DSM 12168 hypothetical-like protein YP_004440650.1 2485033 D 906968 CDS YP_004440651.1 332298729 10580634 complement(2485972..2486178) 1 NC_015500.1 COGs: COG0254 Ribosomal protein L31; HAMAP: 50S ribosomal protein L31; InterPro IPR002150; KEGG: ssm:Spirs_3178 ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: Ribosomal protein L31; IMG reference gene:2504921022; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31; 50S ribosomal protein L31 2486178 10580634 Trebr_2105 Treponema brennaborense DSM 12168 50S ribosomal protein L31 YP_004440651.1 2485972 R 906968 CDS YP_004440652.1 332298730 10580635 complement(2486297..2488030) 1 NC_015500.1 COGs: COG1158 Transcription termination factor; InterProIPR004665:IPR011129:IPR003593:IPR011112:IPR 011113:IPR000194; KEGG: tpp:TPASS_0254 transcription termination factor Rho; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; Rho termination factor, RNA-binding; Rho termination factor, N-terminal; SMART: Cold shock protein; ATPase, AAA+ type, core; SPTR: Transcription termination factor Rho; TIGRFAM: Transcription termination factor Rho; IMG reference gene:2504921023; PFAM: Rho termination factor, N-terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; Rho termination factor, RNA-binding domain; TIGRFAM: transcription termination factor Rho; transcription termination factor Rho 2488030 10580635 Trebr_2106 Treponema brennaborense DSM 12168 transcription termination factor Rho YP_004440652.1 2486297 R 906968 CDS YP_004440653.1 332298731 10580636 2488313..2489587 1 NC_015500.1 KEGG: seu:SEQ_0938 Mac family protein; SPTR: Mac family protein; IMG reference gene:2504921024; PFAM: Mac 1; hypothetical protein 2489587 10580636 Trebr_2107 Treponema brennaborense DSM 12168 hypothetical protein YP_004440653.1 2488313 D 906968 CDS YP_004440654.1 332298732 10580637 2489836..2490243 1 NC_015500.1 IMG reference gene:2504921025; hypothetical protein 2490243 10580637 Trebr_2108 Treponema brennaborense DSM 12168 hypothetical protein YP_004440654.1 2489836 D 906968 CDS YP_004440655.1 332298733 10580638 2490233..2491273 1 NC_015500.1 COGs: COG2933 SAM-dependent methyltransferase; KEGG: tde:TDE2541 hypothetical protein; SPTR: Methyltransferase; IMG reference gene:2504921026; PFAM: FtsJ-like methyltransferase; hypothetical protein 2491273 10580638 Trebr_2109 Treponema brennaborense DSM 12168 hypothetical protein YP_004440655.1 2490233 D 906968 CDS YP_004440656.1 332298734 10580639 complement(2491266..2492183) 1 NC_015500.1 COGs: COG1897 Homoserine trans-succinylase; HAMAP: Homoserine O-succinyltransferase; InterPro IPR005697; KEGG: homoserine O-succinyltransferase; PFAM: Homoserine O-succinyltransferase; PRIAM: Homoserine O-succinyltransferase; SPTR: Homoserine O-succinyltransferase; TIGRFAM: Homoserine O-succinyltransferase; IMG reference gene:2504921027; PFAM: Homoserine O-succinyltransferase; TIGRFAM: homoserine O-succinyltransferase; Homoserine O-succinyltransferase 2492183 10580639 Trebr_2110 Treponema brennaborense DSM 12168 Homoserine O-succinyltransferase YP_004440656.1 2491266 R 906968 CDS YP_004440657.1 332298735 10580640 2492232..2493209 1 NC_015500.1 COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: tde:TDE2263 acetyl hydrolase, SPTR: Acetyl hydrolase, ; IMG reference gene:2504921028; PFAM: alpha/beta hydrolase fold; acetyl hydrolase 2493209 10580640 Trebr_2111 Treponema brennaborense DSM 12168 acetyl hydrolase YP_004440657.1 2492232 D 906968 CDS YP_004440658.1 332298736 10580641 2493197..2494648 1 NC_015500.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: tde:TDE2262 U32 family peptidase; PFAM: Peptidase U32; SPTR: Peptidase, U32 family; IMG reference gene:2504921029; PFAM: Peptidase family U32; peptidase U32 2494648 10580641 Trebr_2112 Treponema brennaborense DSM 12168 peptidase U32 YP_004440658.1 2493197 D 906968 CDS YP_004440659.1 332298737 10580642 complement(2494882..2496729) 1 NC_015500.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR004811:IPR003607:IPR006674:IPR007685:IPR 004095; KEGG: sta:STHERM_c19300 GTP pyrophosphokinase; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD region, subdomain; TGS; PRIAM: GTP diphosphokinase; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: GTP pyrophosphokinase; TIGRFAM: RelA/SpoT protein; IMG reference gene:2504921030; PFAM: TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family; (p)ppGpp synthetase I SpoT/RelA 2496729 10580642 Trebr_2113 Treponema brennaborense DSM 12168 (p)ppGpp synthetase I SpoT/RelA YP_004440659.1 2494882 R 906968 CDS YP_004440660.1 332298738 10580643 complement(2496726..2497766) 1 NC_015500.1 COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR004556:IPR019874:IPR007848; KEGG: tpp:TPASS_0052 protoporphyrinogen oxidase; PFAM: Methyltransferase small; SPTR: Protein-(Glutamine-N5) methyltransferase, release factor-specific; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK; IMG reference gene:2504921031; PFAM: Methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific; protein-(glutamine-N5) methyltransferase 2497766 10580643 Trebr_2114 Treponema brennaborense DSM 12168 protein-(glutamine-N5) methyltransferase YP_004440660.1 2496726 R 906968 CDS YP_004440661.1 332298739 10580644 complement(2497769..2498848) 1 NC_015500.1 COGs: COG0216 Protein chain release factor A; HAMAP: Peptide chain release factor 1; InterPro IPR004373:IPR005139:IPR000352; KEGG: tde:TDE2489 peptide chain release factor 1; PFAM: Class I peptide chain release factor; Peptide chain release factor; SPTR: Peptide chain release factor 1; TIGRFAM: Peptide chain release factor 1; IMG reference gene:2504921032; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1; Peptide chain release factor 1 2498848 10580644 Trebr_2115 Treponema brennaborense DSM 12168 Peptide chain release factor 1 YP_004440661.1 2497769 R 906968 CDS YP_004440662.1 332298740 10580645 2499027..2499614 1 NC_015500.1 InterPro IPR001647; KEGG: csh:Closa_2674 transcriptional regulator, TetR family; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: uncharacterized protein; IMG reference gene:2504921033; PFAM: Bacterial regulatory proteins, tetR family; TIGRFAM: probable dihydroxyacetone kinase regulator; TetR family transcriptional regulator 2499614 10580645 Trebr_2116 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004440662.1 2499027 D 906968 CDS YP_004440663.1 332298741 10580646 2499804..2501579 1 NC_015500.1 COGs: COG4716 Myosin-crossreactive antigen; InterPro IPR010354; KEGG: smu:SMU.515 myosin-cross-reactive antigen; PFAM: Streptococcal 67kDa myosin-cross-reactive antigen like; SPTR: uncharacterized protein; IMG reference gene:2504921034; PFAM: Streptococcal 67 kDa myosin-cross-reactive antigen like family; 67 kDa myosin-cross-reactive antigen family protein 2501579 10580646 Trebr_2117 Treponema brennaborense DSM 12168 67 kDa myosin-cross-reactive antigen family protein YP_004440663.1 2499804 D 906968 CDS YP_004440664.1 332298742 10580647 2501822..2502376 1 NC_015500.1 COGs: COG4843 conserved hypothetical protein; InterPro IPR019264; KEGG: cbf:CLI_0673 hypothetical protein; PFAM: Protein of unknown function DUF2179; SPTR: UPF0316 protein CBF_0642; IMG reference gene:2504921035; PFAM: Uncharacterized protein conserved in bacteria (DUF2179); hypothetical protein 2502376 10580647 Trebr_2118 Treponema brennaborense DSM 12168 hypothetical protein YP_004440664.1 2501822 D 906968 CDS YP_004440665.1 332298743 10580652 complement(2507881..2508075) 1 NC_015500.1 IMG reference gene:2504921040; hypothetical protein 2508075 10580652 Trebr_2119 Treponema brennaborense DSM 12168 hypothetical protein YP_004440665.1 2507881 R 906968 CDS YP_004440666.1 332298744 10580653 complement(2508288..2509517) 1 NC_015500.1 COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: drt:Dret_2291 YibE/F family protein; PFAM: YibE/F-like; SPTR: uncharacterized protein; IMG reference gene:2504921041; PFAM: YibE/F-like protein; hypothetical protein 2509517 10580653 Trebr_2120 Treponema brennaborense DSM 12168 hypothetical protein YP_004440666.1 2508288 R 906968 CDS YP_004440667.1 332298745 10580654 complement(2509611..2511302) 1 NC_015500.1 COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: ccb:Clocel_2509 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference gene:2504921042; PFAM: Alkaline phosphatase; alkaline phosphatase 2511302 10580654 Trebr_2121 Treponema brennaborense DSM 12168 alkaline phosphatase YP_004440667.1 2509611 R 906968 CDS YP_004440668.1 332298746 10580655 complement(2511513..2512103) 1 NC_015500.1 COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: tde:TDE2572 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; IMG reference gene:2504921043; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase 2512103 10580655 Trebr_2122 Treponema brennaborense DSM 12168 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase YP_004440668.1 2511513 R 906968 CDS YP_004440669.1 332298747 10580656 complement(2512152..2512880) 1 NC_015500.1 IMG reference gene:2504921044; hypothetical protein 2512880 10580656 Trebr_2123 Treponema brennaborense DSM 12168 hypothetical protein YP_004440669.1 2512152 R 906968 CDS YP_004440670.1 332298748 10580657 complement(2512877..2513698) 1 NC_015500.1 InterPro IPR007055; KEGG: tde:TDE0009 hypothetical protein; PFAM: Transport-associated; SPTR: Phospholipid-binding domain protein; IMG reference gene:2504921045; transport-associated protein 2513698 10580657 Trebr_2124 Treponema brennaborense DSM 12168 transport-associated protein YP_004440670.1 2512877 R 906968 CDS YP_004440671.1 332298749 10580658 2513796..2514362 1 NC_015500.1 InterPro IPR000086; KEGG: tde:TDE0010 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2504921046; PFAM: NUDIX domain; NUDIX hydrolase 2514362 10580658 Trebr_2125 Treponema brennaborense DSM 12168 NUDIX hydrolase YP_004440671.1 2513796 D 906968 CDS YP_004440672.1 332298750 10580659 complement(2514427..2515122) 1 NC_015500.1 KEGG: tpp:TPASS_0769 outer membrane protein; SPTR: Outer membrane protein; IMG reference gene:2504921047; hypothetical protein 2515122 10580659 Trebr_2126 Treponema brennaborense DSM 12168 hypothetical protein YP_004440672.1 2514427 R 906968 CDS YP_004440673.1 332298751 10580660 complement(2515119..2516057) 1 NC_015500.1 KEGG: bmv:BMASAVP1_0977 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921048; hypothetical protein 2516057 10580660 Trebr_2127 Treponema brennaborense DSM 12168 hypothetical protein YP_004440673.1 2515119 R 906968 CDS YP_004440674.1 332298752 10580661 2516284..2516508 1 NC_015500.1 COGs: COG4443 conserved hypothetical protein; InterPro IPR017154; KEGG: tde:TDE2571 hypothetical protein; PFAM: Uncharacterised conserved protein UCP037246; SPTR: uncharacterized protein; IMG reference gene:2504921049; PFAM: Uncharacterized protein conserved in bacteria (DUF2128); hypothetical protein 2516508 10580661 Trebr_2128 Treponema brennaborense DSM 12168 hypothetical protein YP_004440674.1 2516284 D 906968 CDS YP_004440675.1 332298753 10580662 complement(2516503..2517549) 1 NC_015500.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: tde:TDE0729 hypothetical protein; PFAM: DNA polymerase III, delta; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, delta subunit; IMG reference gene:2504921050; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; DNA polymerase III subunit delta 2517549 10580662 Trebr_2129 Treponema brennaborense DSM 12168 DNA polymerase III subunit delta YP_004440675.1 2516503 R 906968 CDS YP_004440676.1 332298754 10580663 complement(2517546..2518160) 1 NC_015500.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); HAMAP: LexA repressor; InterPro IPR006200:IPR006199:IPR019759; KEGG: ssm:Spirs_4055 transcriptional repressor, LexA family; PFAM: Peptidase S24/S26A/S26B, conserved region; LexA DNA-binding region; SPTR: LexA repressor; TIGRFAM: Peptidase S24, LexA repressor; IMG reference gene:2504921051; PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA; SOS-response transcriptional repressor, LexA 2518160 10580663 Trebr_2130 Treponema brennaborense DSM 12168 SOS-response transcriptional repressor, LexA YP_004440676.1 2517546 R 906968 CDS YP_004440677.1 332298755 10580664 complement(2518167..2518433) 1 NC_015500.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: ssm:Spirs_4051 phosphotransferase system, phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; IMG reference gene:2504921052; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; phosphotransferase system, phosphocarrier protein HPr 2518433 10580664 Trebr_2131 Treponema brennaborense DSM 12168 phosphotransferase system, phosphocarrier protein HPr YP_004440677.1 2518167 R 906968 CDS YP_004440678.1 332298756 10580665 complement(2518501..2519646) 1 NC_015500.1 COGs: COG1493 Serine kinase of the HPr protein regulates carbohydrate metabolism; HAMAP: HPr kinase/phosphorylase; InterPro IPR003755:IPR011126:IPR011104; KEGG: ssm:Spirs_4050 HPr kinase; PFAM: Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal; Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal; SPTR: HPr kinase/phosphorylase; TIGRFAM: Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase; IMG reference gene:2504921053; PFAM: HPr Serine kinase N terminus; HPr Serine kinase C-terminal domain; TIGRFAM: Hpr(Ser) kinase/phosphatase; HPr kinase 2519646 10580665 Trebr_2132 Treponema brennaborense DSM 12168 HPr kinase YP_004440678.1 2518501 R 906968 CDS YP_004440679.1 332298757 10580666 complement(2519679..2519969) 1 NC_015500.1 KEGG: tde:TDE1296 ribosomal subunit interface protein, SPTR: Ribosomal subunit interface protein, ; IMG reference gene:2504921054; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; ribosomal subunit interface protein 2519969 10580666 Trebr_2133 Treponema brennaborense DSM 12168 ribosomal subunit interface protein YP_004440679.1 2519679 R 906968 CDS YP_004440680.1 332298758 10580667 2520259..2521023 1 NC_015500.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: tde:TDE2576 RNA pseudouridylate synthase family protein; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Ribosomal large subunit pseudouridine synthase D; IMG reference gene:2504921055; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; pseudouridine synthase 2521023 10580667 Trebr_2134 Treponema brennaborense DSM 12168 pseudouridine synthase YP_004440680.1 2520259 D 906968 CDS YP_004440681.1 332298759 10580668 complement(2521151..2522434) 1 NC_015500.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: aar:Acear_0620 protein of unknown function DUF21; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SPTR: uncharacterized protein; IMG reference gene:2504921056; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; hypothetical protein 2522434 10580668 Trebr_2135 Treponema brennaborense DSM 12168 hypothetical protein YP_004440681.1 2521151 R 906968 CDS YP_004440682.1 332298760 10580669 complement(2522431..2523735) 1 NC_015500.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: tde:TDE0321 CBS domain-containing protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SPTR: CBS domain protein; IMG reference gene:2504921057; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; hypothetical protein 2523735 10580669 Trebr_2136 Treponema brennaborense DSM 12168 hypothetical protein YP_004440682.1 2522431 R 906968 CDS YP_004440683.1 332298761 10580670 complement(2523736..2524728) 1 NC_015500.1 KEGG: tde:TDE0117 lipoprotein; SPTR: lipoprotein; IMG reference gene:2504921058; hypothetical protein 2524728 10580670 Trebr_2137 Treponema brennaborense DSM 12168 hypothetical protein YP_004440683.1 2523736 R 906968 CDS YP_004440684.1 332298762 10580671 complement(2524790..2529022) 1 NC_015500.1 COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR010141:IPR010918; KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; IMG reference gene:2504921059; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II; phosphoribosylformylglycinamidine synthase 2529022 10580671 Trebr_2138 Treponema brennaborense DSM 12168 phosphoribosylformylglycinamidine synthase YP_004440684.1 2524790 R 906968 CDS YP_004440685.1 332298763 10580672 complement(2529263..2529679) 1 NC_015500.1 COGs: COG1186 Protein chain release factor B; InterPro IPR000352; KEGG: sfu:Sfum_2311 class I peptide chain release factor; PFAM: Class I peptide chain release factor; SPTR: Class I peptide chain release factor; IMG reference gene:2504921060; PFAM: RF-1 domain; class I peptide chain release factor 2529679 10580672 Trebr_2139 Treponema brennaborense DSM 12168 class I peptide chain release factor YP_004440685.1 2529263 R 906968 CDS YP_004440686.1 332298764 10580673 2529806..2530567 1 NC_015500.1 KEGG: tde:TDE1699 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921061; hypothetical protein 2530567 10580673 Trebr_2140 Treponema brennaborense DSM 12168 hypothetical protein YP_004440686.1 2529806 D 906968 CDS YP_004440687.1 332298765 10580674 2530564..2531421 1 NC_015500.1 COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: tde:TDE1698 serine/threonine protein phosphatase family protein; PFAM: Metallophosphoesterase; SPTR: Serine/threonine protein phosphatase family protein; IMG reference gene:2504921062; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase 2531421 10580674 Trebr_2141 Treponema brennaborense DSM 12168 metallophosphoesterase YP_004440687.1 2530564 D 906968 CDS YP_004440688.1 332298766 10580675 2531662..2532147 1 NC_015500.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019888:IPR019887; KEGG: cth:Cthe_0362 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type, C-terminal; SMART: Transcription regulator, AsnC-type; SPTR: Transcriptional regulator, AsnC family; IMG reference gene:2504921063; PFAM: AsnC family; transcriptional regulator, AsnC family 2532147 10580675 Trebr_2142 Treponema brennaborense DSM 12168 transcriptional regulator, AsnC family YP_004440688.1 2531662 D 906968 CDS YP_004440689.1 332298767 10580676 2532147..2533316 1 NC_015500.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: bcl:ABC2913 hypothetical protein; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504921064; PFAM: Aminotransferase class I and II; aspartate transaminase 2533316 10580676 Trebr_2143 Treponema brennaborense DSM 12168 aspartate transaminase YP_004440689.1 2532147 D 906968 CDS YP_004440690.1 332298768 10580677 complement(2533458..2535578) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: tde:TDE2549 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504921065; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2535578 10580677 Trebr_2144 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440690.1 2533458 R 906968 CDS YP_004440691.1 332298769 10580678 2535649..2537934 1 NC_015500.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003593:IPR003439:IPR003339; KEGG: bll:BLJ_1432 fused ATP-binding protein and permease of ABC transporter; PFAM: ABC transporter-like; Cobalt transport protein; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP-binding protein; IMG reference gene:2504921066; PFAM: ABC transporter; Cobalt transport protein; ABC transporter 2537934 10580678 Trebr_2145 Treponema brennaborense DSM 12168 ABC transporter YP_004440691.1 2535649 D 906968 CDS YP_004440692.1 332298770 10580679 2537952..2538569 1 NC_015500.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: geo:Geob_0568 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; IMG reference gene:2504921067; PFAM: NUDIX domain; NUDIX hydrolase 2538569 10580679 Trebr_2146 Treponema brennaborense DSM 12168 NUDIX hydrolase YP_004440692.1 2537952 D 906968 CDS YP_004440693.1 332298771 10580680 2538578..2539630 1 NC_015500.1 COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: lbf:LBF_0668 Ca2+/Na+ antiporter; PFAM: Sodium/calcium exchanger membrane region; SPTR: cation exchanger; membrane protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like; IMG reference gene:2504921068; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; CaCA family Na+/Ca+ antiporter 2539630 10580680 Trebr_2147 Treponema brennaborense DSM 12168 CaCA family Na+/Ca+ antiporter YP_004440693.1 2538578 D 906968 CDS YP_004440694.1 332298772 10580681 2539688..2541196 1 NC_015500.1 KEGG: tde:TDE2285 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921069; hypothetical protein 2541196 10580681 Trebr_2148 Treponema brennaborense DSM 12168 hypothetical protein YP_004440694.1 2539688 D 906968 CDS YP_004440695.1 332298773 10580682 2541196..2542341 1 NC_015500.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: tpp:TPASS_0965 possible membrane fusion protein; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504921070; PFAM: HlyD family secretion protein; RND family efflux transporter MFP subunit 2542341 10580682 Trebr_2149 Treponema brennaborense DSM 12168 RND family efflux transporter MFP subunit YP_004440695.1 2541196 D 906968 CDS YP_004440696.1 332298774 10580683 2542365..2543078 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE0535 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504921071; PFAM: ABC transporter; Phosphonate-transporting ATPase 2543078 10580683 Trebr_2150 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004440696.1 2542365 D 906968 CDS YP_004440697.1 332298775 10580684 2543071..2544261 1 NC_015500.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c10100 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: uncharacterized protein; IMG reference gene:2504921072; PFAM: Predicted permease; hypothetical protein 2544261 10580684 Trebr_2151 Treponema brennaborense DSM 12168 hypothetical protein YP_004440697.1 2543071 D 906968 CDS YP_004440698.1 332298776 10580685 complement(2544350..2545561) 1 NC_015500.1 COGs: COG3007 Uncharacterized paraquat-inducible protein B; HAMAP: Uncharacterised protein family, TER reductase; InterPro IPR010758; KEGG: fsu:Fisuc_0738 trans-2-enoyl-CoA reductase; PFAM: Uncharacterised protein family, TER reductase; PRIAM: Trans-2-enoyl-CoA reductase (NAD(+)); SPTR: reductase FSU_1176/Fisuc_0738; IMG reference gene:2504921073; PFAM: Trans-2-enoyl-CoA reductase catalytic region; NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Enoyl reductase FAD binding domain; reductase 2545561 10580685 Trebr_2152 Treponema brennaborense DSM 12168 reductase YP_004440698.1 2544350 R 906968 CDS YP_004440699.1 332298777 10580686 complement(2545601..2546860) 1 NC_015500.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR017568; KEGG: tde:TDE0038 3-oxoacyl-(acyl-carrier-protein) synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 2; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; IMG reference gene:2504921074; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-ACP synthase II 2546860 10580686 Trebr_2153 Treponema brennaborense DSM 12168 3-oxoacyl-ACP synthase II YP_004440699.1 2545601 R 906968 CDS YP_004440700.1 332298778 10580687 complement(2547066..2548757) 1 NC_015500.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: fsu:Fisuc_3031 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504921075; PFAM: AMP-binding enzyme; butyrate--CoA ligase 2548757 10580687 Trebr_2154 Treponema brennaborense DSM 12168 butyrate--CoA ligase YP_004440700.1 2547066 R 906968 CDS YP_004440701.1 332298779 10580688 2549049..2549360 1 NC_015500.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; IMG reference gene:2504921076; PFAM: Thioredoxin; TIGRFAM: thioredoxin; thioredoxin 2549360 10580688 Trebr_2155 Treponema brennaborense DSM 12168 thioredoxin YP_004440701.1 2549049 D 906968 CDS YP_004440702.1 332298780 10580689 2549570..2550094 1 NC_015500.1 InterPro IPR005648; KEGG: eel:EUBELI_01249 polysaccharide lyase family 1 modular protein with two candidate pectate lyase domains; PFAM: Flagellar hook capping protein; SPTR: Polysaccharide Lyase Family 1 modular protein with two candidate pectate lyase domains; IMG reference gene:2504921077; flagellar hook capping protein 2550094 10580689 Trebr_2156 Treponema brennaborense DSM 12168 flagellar hook capping protein YP_004440702.1 2549570 D 906968 CDS YP_004440703.1 332298781 10580690 2550262..2553228 1 NC_015500.1 InterPro IPR003961:IPR006626; KEGG: cpy:Cphy_3869 fibronectin type III domain-containing protein; PFAM: Fibronectin, type III; PRIAM: Pectate disaccharide-lyase; SMART: Fibronectin, type III; Parallel beta-helix repeat; SPTR: uncharacterized protein; IMG reference gene:2504921078; PFAM: Fibronectin type III domain; Pectate disaccharide-lyase 2553228 10580690 Trebr_2157 Treponema brennaborense DSM 12168 Pectate disaccharide-lyase YP_004440703.1 2550262 D 906968 CDS YP_004440704.1 332298782 10580691 2553458..2554015 1 NC_015500.1 KEGG: rba:RB5302 signal peptide; SPTR: uncharacterized protein; IMG reference gene:2504921079; hypothetical protein 2554015 10580691 Trebr_2158 Treponema brennaborense DSM 12168 hypothetical protein YP_004440704.1 2553458 D 906968 CDS YP_004440705.1 332298783 10580693 2555407..2557191 1 NC_015500.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR004792; KEGG: ppn:Palpr_0173 monooxygenase fad-binding protein; PFAM: HI0933-like protein; SPTR: Monooxygenase FAD-binding protein; IMG reference gene:2504921081; PFAM: FAD binding domain; hypothetical protein 2557191 10580693 Trebr_2160 Treponema brennaborense DSM 12168 hypothetical protein YP_004440705.1 2555407 D 906968 CDS YP_004440706.1 332298784 10580694 complement(2557278..2558654) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: aoe:Clos_0947 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504921082; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 2558654 10580694 Trebr_2161 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004440706.1 2557278 R 906968 CDS YP_004440707.1 332298785 10580695 complement(2558797..2559714) 1 NC_015500.1 InterPro IPR000620; KEGG: csh:Closa_1874 protein of unknown function DUF6 transmembrane; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Predicted permease, DMT superfamily; IMG reference gene:2504921083; PFAM: EamA-like transporter family; hypothetical protein 2559714 10580695 Trebr_2162 Treponema brennaborense DSM 12168 hypothetical protein YP_004440707.1 2558797 R 906968 CDS YP_004440708.1 332298786 10580696 complement(2559928..2560578) 1 NC_015500.1 InterPro IPR009501; KEGG: cbe:Cbei_2882 hypothetical protein; PFAM: Protein of unknown function DUF1121; SPTR: uncharacterized protein; IMG reference gene:2504921084; PFAM: Uncharacterised ACR, YkgG family COG1556; hypothetical protein 2560578 10580696 Trebr_2163 Treponema brennaborense DSM 12168 hypothetical protein YP_004440708.1 2559928 R 906968 CDS YP_004440709.1 332298787 10580697 2560771..2561757 1 NC_015500.1 COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389:IPR004682; KEGG: fnu:FN1472 N-acetylneuraminate-binding protein; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: N-acetylneuraminate-binding protein; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; IMG reference gene:2504921085; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP 2561757 10580697 Trebr_2164 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctP YP_004440709.1 2560771 D 906968 CDS YP_004440710.1 332298788 10580698 2561863..2562336 1 NC_015500.1 COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: vvy:VVA1201 TRAP-type C4-dicarboxylate transport system, small permease component; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Trap-type c4-dicarboxylate transport system, small permease component; IMG reference gene:2504921086; PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; tripartite AtP-independent periplasmic transporter subunit DctQ 2562336 10580698 Trebr_2165 Treponema brennaborense DSM 12168 tripartite AtP-independent periplasmic transporter subunit DctQ YP_004440710.1 2561863 D 906968 CDS YP_004440711.1 332298789 10580699 2562333..2563616 1 NC_015500.1 COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR010656:IPR004681; KEGG: vvy:VVA1200 TRAP-type C4-dicarboxylate transport system, large permease component; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP-type C4-dicarboxylate transport system, large permease component; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; IMG reference gene:2504921087; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; TRAP dicarboxylate transporter subunit DctM 2563616 10580699 Trebr_2166 Treponema brennaborense DSM 12168 TRAP dicarboxylate transporter subunit DctM YP_004440711.1 2562333 D 906968 CDS YP_004440712.1 332298790 10580700 2563695..2564144 1 NC_015500.1 COGs: COG2731 Beta-galactosidase beta subunit; InterPro IPR004375; KEGG: pmr:PMI2975 hypothetical protein; PFAM: Conserved hypothetical protein CHP00022; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00022; IMG reference gene:2504921088; PFAM: Domain of unknown function (DUF386); TIGRFAM: uncharacterized protein, YhcH/YjgK/YiaL family; hypothetical protein 2564144 10580700 Trebr_2167 Treponema brennaborense DSM 12168 hypothetical protein YP_004440712.1 2563695 D 906968 CDS YP_004440713.1 332298791 10580701 complement(2564146..2564961) 1 NC_015500.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130; KEGG: cac:CA_C1397 hydrolase of PHP superfamily; PFAM: Deoxyribonuclease, TatD-related; SPTR: Predicted hydrolase of PHP superfamily; IMG reference gene:2504921089; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; TatD-related deoxyribonuclease 2564961 10580701 Trebr_2168 Treponema brennaborense DSM 12168 TatD-related deoxyribonuclease YP_004440713.1 2564146 R 906968 CDS YP_004440714.1 332298792 10580702 2565190..2566227 1 NC_015500.1 COGs: COG4586 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cpr:CPR_0172 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP-binding protein; IMG reference gene:2504921090; PFAM: ABC transporter; ABC transporter 2566227 10580702 Trebr_2169 Treponema brennaborense DSM 12168 ABC transporter YP_004440714.1 2565190 D 906968 CDS YP_004440715.1 332298793 10580703 2566224..2567075 1 NC_015500.1 COGs: COG4587 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: cpr:CPR_0171 ABC transporter permease; PFAM: Protein of unknown function DUF990; SPTR: uncharacterized protein CPE0181; IMG reference gene:2504921091; PFAM: Protein of unknown function (DUF990); hypothetical protein 2567075 10580703 Trebr_2170 Treponema brennaborense DSM 12168 hypothetical protein YP_004440715.1 2566224 D 906968 CDS YP_004440716.1 332298794 10580704 2567263..2568060 1 NC_015500.1 COGs: COG3694 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: cpe:CPE0180 hypothetical protein; PFAM: Protein of unknown function DUF990; SPTR: uncharacterized protein; IMG reference gene:2504921092; PFAM: Protein of unknown function (DUF990); hypothetical protein 2568060 10580704 Trebr_2171 Treponema brennaborense DSM 12168 hypothetical protein YP_004440716.1 2567263 D 906968 CDS YP_004440717.1 332298795 10580705 complement(2568202..2568459) 1 NC_015500.1 IMG reference gene:2504921093; hypothetical protein 2568459 10580705 Trebr_2172 Treponema brennaborense DSM 12168 hypothetical protein YP_004440717.1 2568202 R 906968 CDS YP_004440718.1 332298796 10580706 complement(2577243..2577530) 1 NC_015500.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: sat:SYN_02472 cytoplasmic protein; SPTR: Hypothetical cytosolic protein; TIGRFAM: Protein of unknown function DUF196; IMG reference gene:2504921094; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2; CRISPR-associated protein Cas2 2577530 10580706 Trebr_2173 Treponema brennaborense DSM 12168 CRISPR-associated protein Cas2 YP_004440718.1 2577243 R 906968 CDS YP_004440719.1 332298797 10580707 complement(2577535..2578566) 1 NC_015500.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019856; KEGG: dma:DMR_14400 hypothetical protein; PFAM: CRISPR-associated protein Cas1; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1, DVULG subtype; CRISPR-associated protein Cas1; IMG reference gene:2504921095; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG; CRISPR-associated endonuclease Cas1; CRISPR-associated protein Cas1 2578566 10580707 Trebr_2174 Treponema brennaborense DSM 12168 CRISPR-associated protein Cas1 YP_004440719.1 2577535 R 906968 CDS YP_004440720.1 332298798 10580708 complement(2578563..2579207) 1 NC_015500.1 COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: sat:SYN_02474 exonuclease N; PFAM: CRISPR-associated protein Cas4; SPTR: RecB family exonuclease N; TIGRFAM: CRISPR-associated protein Cas4; IMG reference gene:2504921096; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4; CRISPR-associated protein Cas4 2579207 10580708 Trebr_2175 Treponema brennaborense DSM 12168 CRISPR-associated protein Cas4 YP_004440720.1 2578563 R 906968 CDS YP_004440721.1 332298799 10580709 complement(2579211..2580053) 1 NC_015500.1 COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482:IPR013418; KEGG: dae:Dtox_3648 CRISPR-associated protein, Csd2 family; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein TM1801; TIGRFAM: CRISPR-associated protein Csd2; CRISPR-associated protein TM1801; IMG reference gene:2504921097; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG; CRISPR-associated protein, Csd2 family 2580053 10580709 Trebr_2176 Treponema brennaborense DSM 12168 CRISPR-associated protein, Csd2 family YP_004440721.1 2579211 R 906968 CDS YP_004440722.1 332298800 10580710 complement(2580055..2581899) 1 NC_015500.1 InterPro IPR010144; KEGG: rrs:RoseRS_4333 CRISPR-associated RAMP Csd1 family protein; PFAM: CRISPR-associated protein, Csd1-type; SPTR: CRISPR-associated protein, Csd1 family; TIGRFAM: CRISPR-associated protein, Csd1-type; IMG reference gene:2504921098; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG; CRISPR-associated protein, Csd1 family 2581899 10580710 Trebr_2177 Treponema brennaborense DSM 12168 CRISPR-associated protein, Csd1 family YP_004440722.1 2580055 R 906968 CDS YP_004440723.1 332298801 10580711 complement(2581896..2582579) 1 NC_015500.1 InterPro IPR010155:IPR013422; KEGG: dae:Dtox_3650 CRISPR-associated protein Cas5 family; PFAM: CRISPR-associated protein, Cas5d-type; SPTR: CRISPR-associated protein Cas5 family; TIGRFAM: CRISPR-associated protein, Cas5d-type; CRISPR-associated protein Cas5; IMG reference gene:2504921099; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, subtype I-C/DVULG; CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5 family 2582579 10580711 Trebr_2178 Treponema brennaborense DSM 12168 CRISPR-associated protein Cas5 family YP_004440723.1 2581896 R 906968 CDS YP_004440724.1 332298802 10580712 complement(2582607..2585069) 1 NC_015500.1 COGs: COG1203 helicase; InterPro IPR014001:IPR006483; KEGG: eba:ebA3291 CRISPR-associated helicase; SMART: DEAD-like helicase, N-terminal; SPTR: Predicted CRISPR-associated helicase; TIGRFAM: CRISPR-associated HD domain; IMG reference gene:2504921100; PFAM: HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; CRISPR-associated HD domain-containing protein 2585069 10580712 Trebr_2179 Treponema brennaborense DSM 12168 CRISPR-associated HD domain-containing protein YP_004440724.1 2582607 R 906968 CDS YP_004440725.1 332298803 10580714 complement(2590635..2591174) 1 NC_015500.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: ere:EUBREC_0646 hypothetical protein; PFAM: NADPH-dependent FMN reductase; SPTR: uncharacterized protein; IMG reference gene:2504921102; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 2591174 10580714 Trebr_2181 Treponema brennaborense DSM 12168 NADPH-dependent FMN reductase YP_004440725.1 2590635 R 906968 CDS YP_004440726.1 332298804 10580716 complement(2592271..2593794) 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cac:CA_C3354 cation efflux pump (multidrug resistance protein); PFAM: Multi antimicrobial extrusion protein MatE; SPTR: Probable cation efflux pump (Multidrug resistance protein); TIGRFAM: Multi antimicrobial extrusion protein MatE; IMG reference gene:2504921104; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 2593794 10580716 Trebr_2183 Treponema brennaborense DSM 12168 MATE efflux family protein YP_004440726.1 2592271 R 906968 CDS YP_004440727.1 332298805 10580717 complement(2593810..2594211) 1 NC_015500.1 IMG reference gene:2504921105; hypothetical protein 2594211 10580717 Trebr_2184 Treponema brennaborense DSM 12168 hypothetical protein YP_004440727.1 2593810 R 906968 CDS YP_004440728.1 332298806 10580718 complement(2594211..2594567) 1 NC_015500.1 IMG reference gene:2504921106; PFAM: PEGA domain; hypothetical protein 2594567 10580718 Trebr_2185 Treponema brennaborense DSM 12168 hypothetical protein YP_004440728.1 2594211 R 906968 CDS YP_004440729.1 332298807 10580719 2594705..2595025 1 NC_015500.1 InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding protein; IMG reference gene:2504921107; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2595025 10580719 Trebr_2186 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440729.1 2594705 D 906968 CDS YP_004440730.1 332298808 10580720 complement(2595032..2595883) 1 NC_015500.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: csh:Closa_3615 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Delta 1-pyrroline-5-carboxylate reductase; IMG reference gene:2504921108; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 2595883 10580720 Trebr_2187 Treponema brennaborense DSM 12168 pyrroline-5-carboxylate reductase YP_004440730.1 2595032 R 906968 CDS YP_004440731.1 332298809 10580721 complement(2595880..2596680) 1 NC_015500.1 COGs: COG0263 Glutamate 5-kinase; HAMAP: Glutamate 5-kinase; InterPro IPR001048:IPR005715; KEGG: amt:Amet_3645 glutamate 5-kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Glutamate 5-kinase; TIGRFAM: Glutamate 5-kinase, ProB-related; IMG reference gene:2504921109; PFAM: Amino acid kinase family; TIGRFAM: glutamate 5-kinase; Glutamate 5-kinase 2596680 10580721 Trebr_2188 Treponema brennaborense DSM 12168 Glutamate 5-kinase YP_004440731.1 2595880 R 906968 CDS YP_004440732.1 332298810 10580722 complement(2596677..2597942) 1 NC_015500.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; HAMAP: Glutamate-5-semialdehyde dehydrogenase; InterPro IPR012134:IPR000965; KEGG: tpp:TPASS_0350 gamma-glutamyl phosphate reductase; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: Gamma-glutamyl phosphate reductase GPR; IMG reference gene:2504921110; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase 2597942 10580722 Trebr_2189 Treponema brennaborense DSM 12168 gamma-glutamyl phosphate reductase YP_004440732.1 2596677 R 906968 CDS YP_004440733.1 332298811 10580723 complement(2597966..2598535) 1 NC_015500.1 KEGG: tde:TDE0022 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921111; hypothetical protein 2598535 10580723 Trebr_2190 Treponema brennaborense DSM 12168 hypothetical protein YP_004440733.1 2597966 R 906968 CDS YP_004440734.1 332298812 10580724 2598743..2599306 1 NC_015500.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; HAMAP: Formylmethionine deformylase; InterPro IPR000181; KEGG: ssm:Spirs_1654 peptide deformylase; PFAM: Formylmethionine deformylase; SPTR: Peptide deformylase; TIGRFAM: Formylmethionine deformylase; IMG reference gene:2504921112; PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase; Peptide deformylase 2599306 10580724 Trebr_2191 Treponema brennaborense DSM 12168 Peptide deformylase YP_004440734.1 2598743 D 906968 CDS YP_004440735.1 332298813 10580725 2599303..2600316 1 NC_015500.1 COGs: COG0223 Methionyl-tRNA formyltransferase; HAMAP: Methionyl-tRNA formyltransferase; InterPro IPR005794:IPR002376:IPR005793; KEGG: sta:STHERM_c20370 methionyl-tRNA formyltransferase; PFAM: Formyl transferase, C-terminal; Formyl transferase, N-terminal; PRIAM: Methionyl-tRNA formyltransferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: Methionyl-tRNA formyltransferase; IMG reference gene:2504921113; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase; Methionyl-tRNA formyltransferase 2600316 10580725 Trebr_2192 Treponema brennaborense DSM 12168 Methionyl-tRNA formyltransferase YP_004440735.1 2599303 D 906968 CDS YP_004440736.1 332298814 10580726 2600320..2601342 1 NC_015500.1 COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: tde:TDE1643 PASTA domain-containing protein; PFAM: PASTA; SMART: PASTA; SPTR: PASTA domain protein; IMG reference gene:2504921114; PFAM: PASTA domain; PASTA domain-containing protein 2601342 10580726 Trebr_2193 Treponema brennaborense DSM 12168 PASTA domain-containing protein YP_004440736.1 2600320 D 906968 CDS YP_004440737.1 332298815 10580727 complement(2601480..2603096) 1 NC_015500.1 COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: bhy:BHWA1_01860 Na+/H+ antiporter; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter NhaC; IMG reference gene:2504921115; PFAM: Na+/H+ antiporter family; Na+/H+ antiporter NhaC 2603096 10580727 Trebr_2194 Treponema brennaborense DSM 12168 Na+/H+ antiporter NhaC YP_004440737.1 2601480 R 906968 CDS YP_004440738.1 332298816 10580728 complement(2603221..2605047) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: ssm:Spirs_3480 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor; IMG reference gene:2504921116; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2605047 10580728 Trebr_2195 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440738.1 2603221 R 906968 CDS YP_004440739.1 332298817 10580729 2605192..2606697 1 NC_015500.1 COGs: COG0169 Shikimate 5-dehydrogenase; HAMAP: Dehydroquinase class I; InterPro IPR001381:IPR013708:IPR006151; KEGG: tde:TDE1640 3-dehydroquinate dehydratase, type 1, /shikimate 5-dehydrogenase, PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Dehydroquinase class I; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: 3-dehydroquinate dehydratase, type 1/shikimate 5-dehydrogenase; IMG reference gene:2504921117; PFAM: Shikimate dehydrogenase substrate binding domain; Type I 3-dehydroquinase; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; 3-dehydroquinate dehydratase, type I; 3-dehydroquinate dehydratase 2606697 10580729 Trebr_2196 Treponema brennaborense DSM 12168 3-dehydroquinate dehydratase YP_004440739.1 2605192 D 906968 CDS YP_004440740.1 332298818 10580730 2606697..2607425 1 NC_015500.1 COGs: COG0120 Ribose 5-phosphate isomerase; HAMAP: Ribose-5-phosphate isomerase, subgroup; InterPro IPR020672:IPR004788; KEGG: tde:TDE1641 ribose-5-phosphate isomerase A; PFAM: Ribose 5-phosphate isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose-5-phosphate isomerase A; TIGRFAM: Ribose 5-phosphate isomerase; IMG reference gene:2504921118; PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); TIGRFAM: ribose 5-phosphate isomerase; ribose-5-phosphate isomerase A 2607425 10580730 Trebr_2197 Treponema brennaborense DSM 12168 ribose-5-phosphate isomerase A YP_004440740.1 2606697 D 906968 CDS YP_004440741.1 332298819 10580731 complement(2607494..2608381) 1 NC_015500.1 KEGG: apr:Apre_1054 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921119; hypothetical protein 2608381 10580731 Trebr_2198 Treponema brennaborense DSM 12168 hypothetical protein YP_004440741.1 2607494 R 906968 CDS YP_004440742.1 332298820 10580732 complement(2608412..2609410) 1 NC_015500.1 COGs: COG1159 GTPase; HAMAP: GTP-binding protein Era; InterPro IPR005662:IPR002917:IPR004044:IPR005225; KEGG: tde:TDE1895 GTP-binding protein Era; PFAM: GTP-binding protein, HSR1-related; K Homology, type 2; SPTR: GTPase Era; TIGRFAM: GTP-binding protein Era; Small GTP-binding protein; IMG reference gene:2504921120; PFAM: GTPase of unknown function; KH domain; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain; GTP-binding protein Era-like-protein 2609410 10580732 Trebr_2199 Treponema brennaborense DSM 12168 GTP-binding protein Era-like-protein YP_004440742.1 2608412 R 906968 CDS YP_004440743.1 332298821 10580733 2609524..2611668 1 NC_015500.1 COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589:IPR004193:IPR006047:IPR011837; KEGG: ssm:Spirs_3465 glycogen debranching enzyme GlgX; PFAM: Glycoside hydrolase, family 13, N-terminal; Glycosyl hydrolase, family 13, catalytic region; PRIAM: Isoamylase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: Glycogen debranching enzyme GlgX; manually curated; IMG reference gene:2504921121; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX; glycogen debranching protein GlgX 2611668 10580733 Trebr_2200 Treponema brennaborense DSM 12168 glycogen debranching protein GlgX YP_004440743.1 2609524 D 906968 CDS YP_004440744.1 332298822 10580734 2611794..2614241 1 NC_015500.1 COGs: COG0058 Glucan phosphorylase; InterPro IPR000811:IPR011833; KEGG: tde:TDE2411 glycogen phosphorylase; PFAM: Glycosyl transferase, family 35; SPTR: Phosphorylase; TIGRFAM: Glycogen/starch/alpha-glucan phosphorylase; IMG reference gene:2504921122; PFAM: Carbohydrate phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; glycogen/starch/alpha-glucan phosphorylase 2614241 10580734 Trebr_2201 Treponema brennaborense DSM 12168 glycogen/starch/alpha-glucan phosphorylase YP_004440744.1 2611794 D 906968 CDS YP_004440745.1 332298823 10580735 complement(2614571..2616046) 1 NC_015500.1 COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR011851:IPR019900; KEGG: mac:MA0003 sodium:proline symporter; PFAM: Sodium/solute symporter; SPTR: Sodium:proline symporter; TIGRFAM: Sodium/proline symporter; Sodium/solute symporter, subgroup; IMG reference gene:2504921123; PFAM: Sodium:solute symporter family; TIGRFAM: sodium/proline symporter; transporter, SSS family; sodium/proline symporter 2616046 10580735 Trebr_2202 Treponema brennaborense DSM 12168 sodium/proline symporter YP_004440745.1 2614571 R 906968 CDS YP_004440746.1 332298824 10580736 2616181..2618478 1 NC_015500.1 COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: cdc:CD196_2722 signaling protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: signaling protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504921124; PFAM: EAL domain; GGDEF domain; diguanylate cyclase/phosphodiesterase 2618478 10580736 Trebr_2203 Treponema brennaborense DSM 12168 diguanylate cyclase/phosphodiesterase YP_004440746.1 2616181 D 906968 CDS YP_004440747.1 332298825 10580737 complement(2618539..2619585) 1 NC_015500.1 COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: tde:TDE0023 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase, gnat family; IMG reference gene:2504921125; PFAM: FR47-like protein; GCN5-related N-acetyltransferase 2619585 10580737 Trebr_2204 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004440747.1 2618539 R 906968 CDS YP_004440748.1 332298826 10580738 complement(2619598..2621376) 1 NC_015500.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: tde:TDE0024 glycosy hydrolase family protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Glycosyl hydrolase, family 3; IMG reference gene:2504921126; PFAM: Glycosyl hydrolase family 3 N terminal domain; glycoside hydrolase family protein 2621376 10580738 Trebr_2205 Treponema brennaborense DSM 12168 glycoside hydrolase family protein YP_004440748.1 2619598 R 906968 CDS YP_004440749.1 332298827 10580739 complement(2621377..2622315) 1 NC_015500.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: tpp:TPASS_0814 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; IMG reference gene:2504921127; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; thioredoxin reductase 2622315 10580739 Trebr_2206 Treponema brennaborense DSM 12168 thioredoxin reductase YP_004440749.1 2621377 R 906968 CDS YP_004440750.1 332298828 10580742 complement(2624679..2625200) 1 NC_015500.1 IMG reference gene:2504921130; hypothetical protein 2625200 10580742 Trebr_2208 Treponema brennaborense DSM 12168 hypothetical protein YP_004440750.1 2624679 R 906968 CDS YP_004440751.1 332298829 10580743 complement(2625273..2625695) 1 NC_015500.1 COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: csh:Closa_3568 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein tyrosine phosphatase; IMG reference gene:2504921131; PFAM: Low molecular weight phosphotyrosine protein phosphatase; protein tyrosine phosphatase 2625695 10580743 Trebr_2209 Treponema brennaborense DSM 12168 protein tyrosine phosphatase YP_004440751.1 2625273 R 906968 CDS YP_004440752.1 332298830 10580744 complement(2625703..2626056) 1 NC_015500.1 InterPro IPR005243; KEGG: redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2; IMG reference gene:2504921132; TIGRFAM: small redox-active disulfide protein 2; redox-active disulfide protein 2 2626056 10580744 Trebr_2210 Treponema brennaborense DSM 12168 redox-active disulfide protein 2 YP_004440752.1 2625703 R 906968 CDS YP_004440753.1 332298831 10580745 complement(2626070..2626513) 1 NC_015500.1 InterPro IPR010181; KEGG: mla:Mlab_0460 hypothetical protein; PFAM: CGCAxxGCC motif; SPTR: C_GCAxxG_C_C family protein; TIGRFAM: CGCAxxGCC motif; IMG reference gene:2504921133; PFAM: redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein; C_GCAxxG_C_C family protein 2626513 10580745 Trebr_2211 Treponema brennaborense DSM 12168 C_GCAxxG_C_C family protein YP_004440753.1 2626070 R 906968 CDS YP_004440754.1 332298832 10580746 complement(2626531..2627544) 1 NC_015500.1 COGs: COG0701 permease; InterPro IPR005524; KEGG: blj:BLD_1092 hypothetical permease; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: uncharacterized protein; IMG reference gene:2504921134; PFAM: Predicted permease; hypothetical protein 2627544 10580746 Trebr_2212 Treponema brennaborense DSM 12168 hypothetical protein YP_004440754.1 2626531 R 906968 CDS YP_004440755.1 332298833 10580747 complement(2627627..2627941) 1 NC_015500.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: cce:Ccel_1065 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: uncharacterized protein; IMG reference gene:2504921135; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 2627941 10580747 Trebr_2213 Treponema brennaborense DSM 12168 ArsR family transcriptional regulator YP_004440755.1 2627627 R 906968 CDS YP_004440756.1 332298834 10580748 2628218..2629321 1 NC_015500.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: str:Sterm_0501 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1; SPTR: Alpha/beta hydrolase fold protein; IMG reference gene:2504921136; PFAM: Prolyl oligopeptidase family; alpha/beta hydrolase fold protein 2629321 10580748 Trebr_2214 Treponema brennaborense DSM 12168 alpha/beta hydrolase fold protein YP_004440756.1 2628218 D 906968 CDS YP_004440757.1 332298835 10580749 2629770..2630450 1 NC_015500.1 COGs: COG2344 AT-rich DNA-binding protein; HAMAP: Redox-sensing transcriptional repressor rex; InterPro IPR003781; KEGG: sta:STHERM_c01510 redox-sensing transcriptional repressor rex; PFAM: CoA-binding; SPTR: Redox-sensing transcriptional repressor rex; IMG reference gene:2504921137; PFAM: CoA binding domain; redox-sensing transcriptional repressor rex 2630450 10580749 Trebr_2215 Treponema brennaborense DSM 12168 redox-sensing transcriptional repressor rex YP_004440757.1 2629770 D 906968 CDS YP_004440758.1 332298836 10580750 2630515..2631627 1 NC_015500.1 COGs: COG1932 Phosphoserine aminotransferase; HAMAP: Phosphoserine aminotransferase; InterPro IPR000192:IPR003248; KEGG: cbe:Cbei_0075 phosphoserine aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Phosphoserine transaminase; SPTR: Phosphoserine aminotransferase; TIGRFAM: Phosphoserine aminotransferase; IMG reference gene:2504921138; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase; Phosphoserine aminotransferase 2631627 10580750 Trebr_2216 Treponema brennaborense DSM 12168 Phosphoserine aminotransferase YP_004440758.1 2630515 D 906968 CDS YP_004440759.1 332298837 10580751 2631808..2632986 1 NC_015500.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: cth:Cthe_3035 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504921139; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Phosphoglycerate dehydrogenase 2632986 10580751 Trebr_2217 Treponema brennaborense DSM 12168 Phosphoglycerate dehydrogenase YP_004440759.1 2631808 D 906968 CDS YP_004440760.1 332298838 10580752 2633176..2633997 1 NC_015500.1 InterPro IPR008258; KEGG: ssm:Spirs_0274 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic; IMG reference gene:2504921140; PFAM: Transglycosylase SLT domain; Lytic transglycosylase catalytic 2633997 10580752 Trebr_2218 Treponema brennaborense DSM 12168 Lytic transglycosylase catalytic YP_004440760.1 2633176 D 906968 CDS YP_004440761.1 332298839 10580753 complement(2634012..2635676) 1 NC_015500.1 KEGG: sta:STHERM_c19870 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921141; hypothetical protein 2635676 10580753 Trebr_2219 Treponema brennaborense DSM 12168 hypothetical protein YP_004440761.1 2634012 R 906968 CDS YP_004440762.1 332298840 10580754 complement(2635801..2636247) 1 NC_015500.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: tpp:TPASS_0085 PTS system, nitrogen regulatory IIA component; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: PTS system, IIA component; IMG reference gene:2504921142; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 2636247 10580754 Trebr_2220 Treponema brennaborense DSM 12168 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_004440762.1 2635801 R 906968 CDS YP_004440763.1 332298841 10580755 2636348..2636752 1 NC_015500.1 KEGG: tde:TDE2505 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921143; hypothetical protein 2636752 10580755 Trebr_2221 Treponema brennaborense DSM 12168 hypothetical protein YP_004440763.1 2636348 D 906968 CDS YP_004440764.1 332298842 10580756 2636753..2637781 1 NC_015500.1 COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR007197; KEGG: tde:TDE2506 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504921144; PFAM: Radical SAM superfamily; Radical SAM domain protein 2637781 10580756 Trebr_2222 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004440764.1 2636753 D 906968 CDS YP_004440765.1 332298843 10580757 2637860..2638840 1 NC_015500.1 KEGG: ssm:Spirs_0126 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921145; hypothetical protein 2638840 10580757 Trebr_2223 Treponema brennaborense DSM 12168 hypothetical protein YP_004440765.1 2637860 D 906968 CDS YP_004440766.1 332298844 10580758 2639376..2640215 1 NC_015500.1 InterPro IPR010106; KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504921146; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 2640215 10580758 Trebr_2224 Treponema brennaborense DSM 12168 hypothetical protein YP_004440766.1 2639376 D 906968 CDS YP_004440767.1 332298845 10580759 complement(2640300..2641277) 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: ssm:Spirs_4268 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-L-fucose synthase; SPTR: NAD-dependent epimerase/dehydratase; IMG reference gene:2504921147; PFAM: NAD dependent epimerase/dehydratase family; GDP-L-fucose synthase 2641277 10580759 Trebr_2225 Treponema brennaborense DSM 12168 GDP-L-fucose synthase YP_004440767.1 2640300 R 906968 CDS YP_004440768.1 332298846 10580760 complement(2641394..2642467) 1 NC_015500.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509:IPR006368; KEGG: amu:Amuc_1249 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase; IMG reference gene:2504921148; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase; GDP-mannose 4,6-dehydratase 2642467 10580760 Trebr_2226 Treponema brennaborense DSM 12168 GDP-mannose 4,6-dehydratase YP_004440768.1 2641394 R 906968 CDS YP_004440769.1 332298847 10580761 complement(2642624..2643706) 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tde:TDE1439 epimerase/dehydratase, PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-N-acetylglucosamine 4-epimerase; SPTR: Epimerase/dehydratase, ; IMG reference gene:2504921149; PFAM: NAD dependent epimerase/dehydratase family; UDP-N-acetylglucosamine 4-epimerase 2643706 10580761 Trebr_2227 Treponema brennaborense DSM 12168 UDP-N-acetylglucosamine 4-epimerase YP_004440769.1 2642624 R 906968 CDS YP_004440770.1 332298848 10580762 complement(2643703..2644482) 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dfe:Dfer_0250 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504921150; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2644482 10580762 Trebr_2228 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440770.1 2643703 R 906968 CDS YP_004440771.1 332298849 10580763 complement(2644519..2645319) 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dfe:Dfer_0250 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504921151; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2645319 10580763 Trebr_2229 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440771.1 2644519 R 906968 CDS YP_004440772.1 332298850 10580764 complement(2645348..2646535) 1 NC_015500.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bcr:BCAH187_A5441 glycosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: glycosyltransferase; IMG reference gene:2504921152; PFAM: Glycosyl transferases group 1; group 1 glycosyl transferase 2646535 10580764 Trebr_2230 Treponema brennaborense DSM 12168 group 1 glycosyl transferase YP_004440772.1 2645348 R 906968 CDS YP_004440773.1 332298851 10580765 complement(2646540..2647256) 1 NC_015500.1 InterPro IPR002509; KEGG: ppn:Palpr_2331 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: endo-1,4-beta-xylanase YjeA; manually curated; IMG reference gene:2504921153; PFAM: Polysaccharide deacetylase; polysaccharide deacetylase 2647256 10580765 Trebr_2231 Treponema brennaborense DSM 12168 polysaccharide deacetylase YP_004440773.1 2646540 R 906968 CDS YP_004440774.1 332298852 10580767 complement(2647534..2648775) 1 NC_015500.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: wch:wcw_0483 transposase; PFAM: Transposase, mutator type; SPTR: Transposase; IMG reference gene:2504921155; PFAM: Transposase, Mutator family; transposase mutator type 2648775 10580767 Trebr_2233 Treponema brennaborense DSM 12168 transposase mutator type YP_004440774.1 2647534 R 906968 CDS YP_004440775.1 332298853 10580769 complement(2649541..2650068) 1 NC_015500.1 KEGG: ssm:Spirs_1333 NusG antitermination factor; SPTR: NusG antitermination factor; IMG reference gene:2504921157; PFAM: KOW motif; hypothetical protein 2650068 10580769 Trebr_2235 Treponema brennaborense DSM 12168 hypothetical protein YP_004440775.1 2649541 R 906968 CDS YP_004440776.1 332298854 10580770 complement(2650122..2650844) 1 NC_015500.1 IMG reference gene:2504921158; hypothetical protein 2650844 10580770 Trebr_2236 Treponema brennaborense DSM 12168 hypothetical protein YP_004440776.1 2650122 R 906968 CDS YP_004440777.1 332298855 10580771 2650989..2651252 1 NC_015500.1 InterPro IPR001387; KEGG: ssm:Spirs_2524 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504921159; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2651252 10580771 Trebr_2237 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004440777.1 2650989 D 906968 CDS YP_004440778.1 332298856 10580772 2651410..2653458 1 NC_015500.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: fsu:Fisuc_0860 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; IMG reference gene:2504921160; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 2653458 10580772 Trebr_2238 Treponema brennaborense DSM 12168 4-alpha-glucanotransferase YP_004440778.1 2651410 D 906968 CDS YP_004440779.1 332298857 10580773 2653593..2657402 1 NC_015500.1 InterPro IPR006589:IPR006047; KEGG: tde:TDE2678 alpha-amylase family protein; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha-amylase family protein; IMG reference gene:2504921161; PFAM: Alpha amylase, catalytic domain; alpha amylase catalytic subunit 2657402 10580773 Trebr_2239 Treponema brennaborense DSM 12168 alpha amylase catalytic subunit YP_004440779.1 2653593 D 906968 CDS YP_004440780.1 332298858 10580774 complement(2657679..2658989) 1 NC_015500.1 COGs: COG0498 Threonine synthase; KEGG: tde:TDE2676 threonine synthase; SPTR: Threonine synthase; IMG reference gene:2504921162; PFAM: Pyridoxal-phosphate dependent enzyme; threonine synthase 2658989 10580774 Trebr_2240 Treponema brennaborense DSM 12168 threonine synthase YP_004440780.1 2657679 R 906968 CDS YP_004440781.1 332298859 10580775 complement(2659037..2659954) 1 NC_015500.1 COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: ssm:Spirs_3910 uncharacterized conserved protein UCP018688; PFAM: Uncharacterised conserved protein UCP018688; SPTR: Uncharacterized conserved protein UCP018688; IMG reference gene:2504921163; PFAM: Uncharacterized conserved protein (DUF2156); hypothetical protein 2659954 10580775 Trebr_2241 Treponema brennaborense DSM 12168 hypothetical protein YP_004440781.1 2659037 R 906968 CDS YP_004440782.1 332298860 10580776 2660147..2661442 1 NC_015500.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR011650:IPR002933:IPR010161; KEGG: ssm:Spirs_3909 peptidase T; PFAM: Peptidase M20, dimerisation; Peptidase M20; PRIAM: Tripeptide aminopeptidase; SPTR: Peptidase T; TIGRFAM: Peptidase M20B, tripeptide aminopeptidase; IMG reference gene:2504921164; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T; peptidase T 2661442 10580776 Trebr_2242 Treponema brennaborense DSM 12168 peptidase T YP_004440782.1 2660147 D 906968 CDS YP_004440783.1 332298861 10580777 2661510..2661752 1 NC_015500.1 KEGG: elm:ELI_2159 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921165; TIGRFAM: uncharacterized protein TIGR03905; hypothetical protein 2661752 10580777 Trebr_2243 Treponema brennaborense DSM 12168 hypothetical protein YP_004440783.1 2661510 D 906968 CDS YP_004440784.1 332298862 10580778 2661745..2663040 1 NC_015500.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; HAMAP: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; InterPro IPR001986:IPR005750; KEGG: tde:TDE0641 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: 3-phosphoshikimate 1-carboxyvinyltransferase, core; PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; IMG reference gene:2504921166; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; UDP-N-acetylglucosamine1- carboxyvinyltransferase 2663040 10580778 Trebr_2244 Treponema brennaborense DSM 12168 UDP-N-acetylglucosamine1- carboxyvinyltransferase YP_004440784.1 2661745 D 906968 CDS YP_004440785.1 332298863 10580779 complement(2663131..2663886) 1 NC_015500.1 InterPro IPR001623; KEGG: zpr:ZPR_0128 DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: DnaJ domain-containing protein; IMG reference gene:2504921167; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 2663886 10580779 Trebr_2245 Treponema brennaborense DSM 12168 heat shock protein DnaJ domain-containing protein YP_004440785.1 2663131 R 906968 CDS YP_004440786.1 332298864 10580780 complement(2663879..2665690) 1 NC_015500.1 KEGG: tde:TDE0867 hypothetical protein; SPTR: lipoprotein; IMG reference gene:2504921168; hypothetical protein 2665690 10580780 Trebr_2246 Treponema brennaborense DSM 12168 hypothetical protein YP_004440786.1 2663879 R 906968 CDS YP_004440787.1 332298865 10580781 complement(2665687..2666616) 1 NC_015500.1 IMG reference gene:2504921169; hypothetical protein 2666616 10580781 Trebr_2247 Treponema brennaborense DSM 12168 hypothetical protein YP_004440787.1 2665687 R 906968 CDS YP_004440788.1 332298866 10580782 complement(2666940..2667491) 1 NC_015500.1 COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: ssm:Spirs_0140 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist; IMG reference gene:2504921170; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 2667491 10580782 Trebr_2248 Treponema brennaborense DSM 12168 anti-sigma-factor antagonist YP_004440788.1 2666940 R 906968 CDS YP_004440789.1 332298867 10580783 complement(2667612..2668346) 1 NC_015500.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c00440 hypothetical protein; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 3-hydroxybutyrate dehydrogenase; IMG reference gene:2504921171; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 2668346 10580783 Trebr_2249 Treponema brennaborense DSM 12168 short-chain dehydrogenase/reductase SDR YP_004440789.1 2667612 R 906968 CDS YP_004440790.1 332298868 10580784 2668392..2669147 1 NC_015500.1 COGs: COG0565 rRNA methylase; InterPro IPR001537; KEGG: ssm:Spirs_2304 RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family, group 1; IMG reference gene:2504921172; PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1; tRNA/rRNA methyltransferase SpoU 2669147 10580784 Trebr_2250 Treponema brennaborense DSM 12168 tRNA/rRNA methyltransferase SpoU YP_004440790.1 2668392 D 906968 CDS YP_004440791.1 332298869 10580785 complement(2669117..2670256) 1 NC_015500.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078; KEGG: dae:Dtox_0789 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; SMART: ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; IMG reference gene:2504921173; PFAM: Sigma-54 interaction domain; sigma-54 interacting domain-containing protein 2670256 10580785 Trebr_2251 Treponema brennaborense DSM 12168 sigma-54 interacting domain-containing protein YP_004440791.1 2669117 R 906968 CDS YP_004440792.1 332298870 10580786 complement(2670281..2671024) 1 NC_015500.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: tde:TDE1876 WecB/TagA/CpsF family glycosyl transferase; PFAM: Glycosyl transferase WecB/TagA/CpsF; SPTR: Glycosyl transferase, WecB/TagA/CpsF family; IMG reference gene:2504921174; PFAM: Glycosyl transferase WecB/TagA/CpsF family; WecB/TagA/CpsF glycosyl transferase 2671024 10580786 Trebr_2252 Treponema brennaborense DSM 12168 WecB/TagA/CpsF glycosyl transferase YP_004440792.1 2670281 R 906968 CDS YP_004440793.1 332298871 10580787 complement(2670997..2671857) 1 NC_015500.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: tpp:TPASS_0276 16S ribosomal RNA methyltransferase RsmE; PFAM: Ribosomal RNA small subunit methyltransferase E; SPTR: RNA methyltransferase family protein; TIGRFAM: Ribosomal RNA small subunit methyltransferase E; IMG reference gene:2504921175; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family; Ribosomal RNA small subunit methyltransferase E 2671857 10580787 Trebr_2253 Treponema brennaborense DSM 12168 Ribosomal RNA small subunit methyltransferase E YP_004440793.1 2670997 R 906968 CDS YP_004440794.1 332298872 10580788 complement(2671859..2673385) 1 NC_015500.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: tpp:TPASS_0277 carboxyl-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxy--processing protease; TIGRFAM: Peptidase S41A, C-terminal protease; IMG reference gene:2504921176; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); carboxyl-terminal protease 2673385 10580788 Trebr_2254 Treponema brennaborense DSM 12168 carboxyl-terminal protease YP_004440794.1 2671859 R 906968 CDS YP_004440795.1 332298873 10580789 2673520..2674014 1 NC_015500.1 IMG reference gene:2504921177; hypothetical protein 2674014 10580789 Trebr_2255 Treponema brennaborense DSM 12168 hypothetical protein YP_004440795.1 2673520 D 906968 CDS YP_004440796.1 332298874 10580790 2674005..2675132 1 NC_015500.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: tde:TDE1397 flagellar synthesis regulator FleN, SPTR: ATP-binding protein; IMG reference gene:2504921178; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; flagellar synthesis regulator FleN 2675132 10580790 Trebr_2256 Treponema brennaborense DSM 12168 flagellar synthesis regulator FleN YP_004440796.1 2674005 D 906968 CDS YP_004440797.1 332298875 10580791 2675145..2676122 1 NC_015500.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; HAMAP: Prolipoprotein diacylglyceryl transferase; InterPro IPR001640; KEGG: sta:STHERM_c00350 prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: Prolipoprotein diacylglyceryl transferase; IMG reference gene:2504921179; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 2676122 10580791 Trebr_2257 Treponema brennaborense DSM 12168 prolipoprotein diacylglyceryl transferase YP_004440797.1 2675145 D 906968 CDS YP_004440798.1 332298876 10580792 complement(2676266..2678233) 1 NC_015500.1 COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476:IPR005478; KEGG: tde:TDE1308 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Transketolase; SPTR: Transketolase; TIGRFAM: Transketolase, bacterial-like; IMG reference gene:2504921180; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; transketolase 2678233 10580792 Trebr_2258 Treponema brennaborense DSM 12168 transketolase YP_004440798.1 2676266 R 906968 CDS YP_004440799.1 332298877 10580793 complement(2678354..2678830) 1 NC_015500.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); KEGG: gur:Gura_0893 PTS IIA-like nitrogen-regulatory protein PtsN; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; IMG reference gene:2504921181; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 2678830 10580793 Trebr_2259 Treponema brennaborense DSM 12168 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_004440799.1 2678354 R 906968 CDS YP_004440800.1 332298878 10580794 complement(2678851..2680326) 1 NC_015500.1 KEGG: tde:TDE1307 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921182; hypothetical protein 2680326 10580794 Trebr_2260 Treponema brennaborense DSM 12168 hypothetical protein YP_004440800.1 2678851 R 906968 CDS YP_004440801.1 332298879 10580795 2680790..2681227 1 NC_015500.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tde:TDE1029 HSP20/alpha crystallin family protein; PFAM: Heat shock protein Hsp20; SPTR: Hsp20/alpha crystallin family protein; IMG reference gene:2504921183; PFAM: Hsp20/alpha crystallin family; heat shock protein Hsp20 2681227 10580795 Trebr_2261 Treponema brennaborense DSM 12168 heat shock protein Hsp20 YP_004440801.1 2680790 D 906968 CDS YP_004440802.1 332298880 10580796 complement(2681383..2682021) 1 NC_015500.1 COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: ssm:Spirs_0348 signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: signal transduction protein with CBS domains; IMG reference gene:2504921184; PFAM: CBS domain; CBS domain-containing membrane protein 2682021 10580796 Trebr_2262 Treponema brennaborense DSM 12168 CBS domain-containing membrane protein YP_004440802.1 2681383 R 906968 CDS YP_004440803.1 332298881 10580797 complement(2682050..2682754) 1 NC_015500.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: hmo:HM1_0494 branched-chain amino acid abc transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Branched-chain amino acid abc transporter, ATP-binding protein; IMG reference gene:2504921185; PFAM: ABC transporter; ABC transporter 2682754 10580797 Trebr_2263 Treponema brennaborense DSM 12168 ABC transporter YP_004440803.1 2682050 R 906968 CDS YP_004440804.1 332298882 10580798 complement(2682754..2683566) 1 NC_015500.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: hmo:HM1_0493 branched chain amino acid abc transporter, PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Branched chain amino acid abc transporter, ; IMG reference gene:2504921186; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; monosaccharide-transporting ATPase 2683566 10580798 Trebr_2264 Treponema brennaborense DSM 12168 monosaccharide-transporting ATPase YP_004440804.1 2682754 R 906968 CDS YP_004440805.1 332298883 10580799 complement(2683559..2684620) 1 NC_015500.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c19050 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Transporter; IMG reference gene:2504921187; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 2684620 10580799 Trebr_2265 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440805.1 2683559 R 906968 CDS YP_004440806.1 332298884 10580800 complement(2684620..2685519) 1 NC_015500.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sta:STHERM_c19060 hypothetical protein; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 1, HAAT family; IMG reference gene:2504921188; PFAM: Branched-chain amino acid transport system / permease component; ABC transporter permease 2685519 10580800 Trebr_2266 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440806.1 2684620 R 906968 CDS YP_004440807.1 332298885 10580801 complement(2685700..2686848) 1 NC_015500.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sta:STHERM_c19070 hypothetical protein; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; IMG reference gene:2504921189; PFAM: Receptor family ligand binding region; extracellular ligand-binding receptor 2686848 10580801 Trebr_2267 Treponema brennaborense DSM 12168 extracellular ligand-binding receptor YP_004440807.1 2685700 R 906968 CDS YP_004440808.1 332298886 10580802 complement(2686979..2687155) 1 NC_015500.1 KEGG: tde:TDE0793 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921190; hypothetical protein 2687155 10580802 Trebr_2268 Treponema brennaborense DSM 12168 hypothetical protein YP_004440808.1 2686979 R 906968 CDS YP_004440809.1 332298887 10580803 complement(2687186..2687704) 1 NC_015500.1 COGs: COG0203 Ribosomal protein L17; HAMAP: 50S ribosomal protein L17; InterPro IPR000456; KEGG: tde:TDE0792 50S ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; IMG reference gene:2504921191; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; 50S ribosomal protein L17 2687704 10580803 Trebr_2269 Treponema brennaborense DSM 12168 50S ribosomal protein L17 YP_004440809.1 2687186 R 906968 CDS YP_004440810.1 332298888 10580804 complement(2687694..2688746) 1 NC_015500.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; HAMAP: DNA-directed RNA polymerase, alpha subunit; InterProIPR011773:IPR011263:IPR011261:IPR011262:IPR 011260; KEGG: ssm:Spirs_0980 DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase, alpha subunit, C-terminal; DNA-directed RNA polymerase, dimerisation; DNA-directed RNA polymerase, insert; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; IMG reference gene:2504921192; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; DNA-directed RNA polymerase subunit alpha 2688746 10580804 Trebr_2270 Treponema brennaborense DSM 12168 DNA-directed RNA polymerase subunit alpha YP_004440810.1 2687694 R 906968 CDS YP_004440811.1 332298889 10580805 complement(2688758..2689393) 1 NC_015500.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR002942:IPR001912:IPR005709; KEGG: ssm:Spirs_0979 ribosomal protein S4; PFAM: RNA-binding S4; Ribosomal protein S4; SMART: RNA-binding S4; SPTR: 30S ribosomal protein S4 1; TIGRFAM: Ribosomal protein S4, bacterial-type; IMG reference gene:2504921193; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type; 30S ribosomal protein S4 2689393 10580805 Trebr_2271 Treponema brennaborense DSM 12168 30S ribosomal protein S4 YP_004440811.1 2688758 R 906968 CDS YP_004440812.1 332298890 10580806 complement(2689412..2689792) 1 NC_015500.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR001971:IPR019981; KEGG: tde:TDE0790 30S ribosomal protein S11; PFAM: Ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: Ribosomal protein S11, bacterial-type; IMG reference gene:2504921194; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; 30S ribosomal protein S11 2689792 10580806 Trebr_2272 Treponema brennaborense DSM 12168 30S ribosomal protein S11 YP_004440812.1 2689412 R 906968 CDS YP_004440813.1 332298891 10580807 complement(2689810..2690175) 1 NC_015500.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR001892:IPR019980; KEGG: tpp:TPASS_0210 30S ribosomal protein S13; PFAM: Ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: Ribosomal protein S13, bacterial-type; IMG reference gene:2504921195; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13; 30S ribosomal protein S13 2690175 10580807 Trebr_2273 Treponema brennaborense DSM 12168 30S ribosomal protein S13 YP_004440813.1 2689810 R 906968 CDS YP_004440814.1 332298892 10580808 complement(2690186..2690299) 1 NC_015500.1 HAMAP: Ribosomal protein L36; InterPro IPR000473; KEGG: tde:TDE0788 50S ribosomal protein L36; PFAM: Ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: Ribosomal protein L36; manually curated; IMG reference gene:2504921196; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; 50S ribosomal protein L36 2690299 10580808 Trebr_2274 Treponema brennaborense DSM 12168 50S ribosomal protein L36 YP_004440814.1 2690186 R 906968 CDS YP_004440815.1 332298893 10580809 complement(2690424..2691743) 1 NC_015500.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: tde:TDE0787 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase, SecY subunit; TIGRFAM: SecY protein; IMG reference gene:2504921197; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit; preprotein translocase subunit SecY 2691743 10580809 Trebr_2275 Treponema brennaborense DSM 12168 preprotein translocase subunit SecY YP_004440815.1 2690424 R 906968 CDS YP_004440816.1 332298894 10580810 complement(2691761..2692213) 1 NC_015500.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR001196:IPR005749; KEGG: tde:TDE0786 50S ribosomal protein L15; PFAM: Ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: Ribosomal protein L15, bacterial-type; IMG reference gene:2504921198; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle; 50S ribosomal protein L15 2692213 10580810 Trebr_2276 Treponema brennaborense DSM 12168 50S ribosomal protein L15 YP_004440816.1 2691761 R 906968 CDS YP_004440817.1 332298895 10580811 complement(2692213..2692398) 1 NC_015500.1 COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR000517:IPR005996; KEGG: tde:TDE0785 50S ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e, conserved region; SPTR: 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; IMG reference gene:2504921199; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle; 50S ribosomal protein L30 2692398 10580811 Trebr_2277 Treponema brennaborense DSM 12168 50S ribosomal protein L30 YP_004440817.1 2692213 R 906968 CDS YP_004440818.1 332298896 10580812 complement(2692402..2692914) 1 NC_015500.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR013810:IPR005324:IPR005712; KEGG: tde:TDE0784 30S ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal; Ribosomal protein S5, C-terminal; SPTR: 30S ribosomal protein S5; TIGRFAM: Ribosomal protein S5, bacterial-type; IMG reference gene:2504921200; PFAM: Ribosomal protein S5, C-terminal domain; Ribosomal protein S5, N-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type; 30S ribosomal protein S5 2692914 10580812 Trebr_2278 Treponema brennaborense DSM 12168 30S ribosomal protein S5 YP_004440818.1 2692402 R 906968 CDS YP_004440819.1 332298897 10580813 complement(2692923..2693285) 1 NC_015500.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR005484:IPR004389; KEGG: tde:TDE0783 50S ribosomal protein L18; PFAM: Ribosomal protein L18/L5; SPTR: 50S ribosomal protein L18; TIGRFAM: Ribosomal protein L18, bacterial; IMG reference gene:2504921201; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type; 50S ribosomal protein L18 2693285 10580813 Trebr_2279 Treponema brennaborense DSM 12168 50S ribosomal protein L18 YP_004440819.1 2692923 R 906968 CDS YP_004440820.1 332298898 10580814 complement(2693298..2693837) 1 NC_015500.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR020040:IPR019906; KEGG: tde:TDE0782 50S ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: Ribosomal protein L6, bacterial-type; IMG reference gene:2504921202; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type; 50S ribosomal protein L6 2693837 10580814 Trebr_2280 Treponema brennaborense DSM 12168 50S ribosomal protein L6 YP_004440820.1 2693298 R 906968 CDS YP_004440821.1 332298899 10580815 complement(2693850..2694248) 1 NC_015500.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: tpp:TPASS_0203 30S ribosomal protein S8; PFAM: Ribosomal protein S8; SPTR: 30S ribosomal protein S8; IMG reference gene:2504921203; PFAM: Ribosomal protein S8; 30S ribosomal protein S8 2694248 10580815 Trebr_2281 Treponema brennaborense DSM 12168 30S ribosomal protein S8 YP_004440821.1 2693850 R 906968 CDS YP_004440822.1 332298900 10580816 complement(2694264..2694449) 1 NC_015500.1 COGs: COG0199 Ribosomal protein S14; InterPro IPR001209; KEGG: ssm:Spirs_0968 ribosomal protein S14; PFAM: Ribosomal protein S14; SPTR: 30S ribosomal protein S14 type Z; IMG reference gene:2504921204; PFAM: Ribosomal protein S14p/S29e; 30S ribosomal protein S14 2694449 10580816 Trebr_2282 Treponema brennaborense DSM 12168 30S ribosomal protein S14 YP_004440822.1 2694264 R 906968 CDS YP_004440823.1 332298901 10580817 complement(2694461..2695012) 1 NC_015500.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR002132; KEGG: tde:TDE0779 50S ribosomal protein L5; PFAM: Ribosomal protein L5; SPTR: 50S ribosomal protein L5; IMG reference gene:2504921205; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5; 50S ribosomal protein L5 2695012 10580817 Trebr_2283 Treponema brennaborense DSM 12168 50S ribosomal protein L5 YP_004440823.1 2694461 R 906968 CDS YP_004440824.1 332298902 10580818 complement(2695012..2695326) 1 NC_015500.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR005824:IPR003256; KEGG: tde:TDE0778 50S ribosomal protein L24; PFAM: KOW; SMART: KOW; SPTR: 50S ribosomal protein L24; TIGRFAM: Ribosomal protein L24; IMG reference gene:2504921206; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle; 50S ribosomal protein L24 2695326 10580818 Trebr_2284 Treponema brennaborense DSM 12168 50S ribosomal protein L24 YP_004440824.1 2695012 R 906968 CDS YP_004440825.1 332298903 10580819 complement(2695353..2695721) 1 NC_015500.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR000218:IPR005745; KEGG: tpp:TPASS_0199 50S ribosomal protein L14; PFAM: Ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: Ribosomal protein L14, bacterial-type; IMG reference gene:2504921207; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle; 50S ribosomal protein L14 2695721 10580819 Trebr_2285 Treponema brennaborense DSM 12168 50S ribosomal protein L14 YP_004440825.1 2695353 R 906968 CDS YP_004440826.1 332298904 10580820 complement(2695739..2696014) 1 NC_015500.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR000266:IPR019984; KEGG: tde:TDE0776 30S ribosomal protein S17; PFAM: Ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: Ribosomal protein S17, bacterial-type; IMG reference gene:2504921208; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; 30S ribosomal protein S17 2696014 10580820 Trebr_2286 Treponema brennaborense DSM 12168 30S ribosomal protein S17 YP_004440826.1 2695739 R 906968 CDS YP_004440827.1 332298905 10580821 complement(2696025..2696225) 1 NC_015500.1 InterPro IPR001854; KEGG: tde:TDE0775 50S ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: Ribosomal protein L29; IMG reference gene:2504921209; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; 50S ribosomal protein L29 2696225 10580821 Trebr_2287 Treponema brennaborense DSM 12168 50S ribosomal protein L29 YP_004440827.1 2696025 R 906968 CDS YP_004440828.1 332298906 10580822 complement(2696236..2696655) 1 NC_015500.1 COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: Ribosomal protein L16; InterPro IPR000114:IPR016180; KEGG: tpp:TPASS_0196 50S ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: Ribosomal protein L16; IMG reference gene:2504921210; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle; 50S ribosomal protein L16 2696655 10580822 Trebr_2288 Treponema brennaborense DSM 12168 50S ribosomal protein L16 YP_004440828.1 2696236 R 906968 CDS YP_004440829.1 332298907 10580823 complement(2696658..2697404) 1 NC_015500.1 COGs: COG0092 Ribosomal protein S3; InterPro IPR008282:IPR004044:IPR001351:IPR005704; KEGG: tde:TDE0773 30S ribosomal protein S3; PFAM: Ribosomal protein S3, C-terminal; Ribosomal protein S3, N-terminal; K Homology, type 2; SPTR: 30S ribosomal protein S3; TIGRFAM: Ribosomal protein S3, bacterial; IMG reference gene:2504921211; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type; 30S ribosomal protein S3 2697404 10580823 Trebr_2289 Treponema brennaborense DSM 12168 30S ribosomal protein S3 YP_004440829.1 2696658 R 906968 CDS YP_004440830.1 332298908 10580824 complement(2697406..2697762) 1 NC_015500.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR001063:IPR005727; KEGG: tde:TDE0772 50S ribosomal protein L22; PFAM: Ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: Ribosomal protein L22, bacterial-type; IMG reference gene:2504921212; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type; 50S ribosomal protein L22 2697762 10580824 Trebr_2290 Treponema brennaborense DSM 12168 50S ribosomal protein L22 YP_004440830.1 2697406 R 906968 CDS YP_004440831.1 332298909 10580825 complement(2697772..2698050) 1 NC_015500.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR002222:IPR005732; KEGG: ssm:Spirs_0959 ribosomal protein S19; PFAM: Ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: Ribosomal protein S19, bacterial-type; manually curated; IMG reference gene:2504921213; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle; 30S ribosomal protein S19 2698050 10580825 Trebr_2291 Treponema brennaborense DSM 12168 30S ribosomal protein S19 YP_004440831.1 2697772 R 906968 CDS YP_004440832.1 332298910 10580826 complement(2698068..2698892) 1 NC_015500.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR002171:IPR005880; KEGG: tde:TDE0770 50S ribosomal protein L2; PFAM: Ribosomal protein L2; SPTR: 50S ribosomal protein L2; TIGRFAM: Ribosomal protein L2, bacterial-type; IMG reference gene:2504921214; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar; 50S ribosomal protein L2 2698892 10580826 Trebr_2292 Treponema brennaborense DSM 12168 50S ribosomal protein L2 YP_004440832.1 2698068 R 906968 CDS YP_004440833.1 332298911 10580827 complement(2698931..2699215) 1 NC_015500.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: tde:TDE0769 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; IMG reference gene:2504921215; PFAM: Ribosomal protein L23; 50S ribosomal protein L25/L23 2699215 10580827 Trebr_2293 Treponema brennaborense DSM 12168 50S ribosomal protein L25/L23 YP_004440833.1 2698931 R 906968 CDS YP_004440834.1 332298912 10580828 complement(2699215..2699847) 1 NC_015500.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: tde:TDE0768 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; IMG reference gene:2504921216; PFAM: Ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle; 50S ribosomal protein L4/L1e 2699847 10580828 Trebr_2294 Treponema brennaborense DSM 12168 50S ribosomal protein L4/L1e YP_004440834.1 2699215 R 906968 CDS YP_004440835.1 332298913 10580829 complement(2699863..2700483) 1 NC_015500.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR000597:IPR019927; KEGG: tde:TDE0767 50S ribosomal protein L3; PFAM: Ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: Ribosomal protein L3, bacterial/organelle-type; IMG reference gene:2504921217; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial; 50S ribosomal protein L3 2700483 10580829 Trebr_2295 Treponema brennaborense DSM 12168 50S ribosomal protein L3 YP_004440835.1 2699863 R 906968 CDS YP_004440836.1 332298914 10580830 complement(2700585..2700893) 1 NC_015500.1 COGs: COG0051 Ribosomal protein S10; HAMAP: 30S ribosomal protein S10; InterPro IPR001848:IPR005731; KEGG: ssm:Spirs_0954 ribosomal protein S10; PFAM: Ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: Ribosomal protein S10, bacterial; IMG reference gene:2504921218; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle; 30S ribosomal protein S10 2700893 10580830 Trebr_2296 Treponema brennaborense DSM 12168 30S ribosomal protein S10 YP_004440836.1 2700585 R 906968 CDS YP_004440837.1 332298915 10580831 complement(2700972..2702159) 1 NC_015500.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004161:IPR004160:IPR004541:IPR 005225; KEGG: tde:TDE0765 elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; IMG reference gene:2504921219; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; translation elongation factor Tu 2702159 10580831 Trebr_2297 Treponema brennaborense DSM 12168 translation elongation factor Tu YP_004440837.1 2700972 R 906968 CDS YP_004440838.1 332298916 10580832 complement(2702743..2703213) 1 NC_015500.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR000235:IPR005717; KEGG: tde:TDE1048 30S ribosomal protein S7; PFAM: Ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: Ribosomal protein S7, bacterial-type; IMG reference gene:2504921220; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle; 30S ribosomal protein S7 2703213 10580832 Trebr_2298 Treponema brennaborense DSM 12168 30S ribosomal protein S7 YP_004440838.1 2702743 R 906968 CDS YP_004440839.1 332298917 10580833 complement(2703226..2703600) 1 NC_015500.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR006032:IPR005679; KEGG: sta:STHERM_c04920 30S ribosomal protein S12; PFAM: Ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: Ribosomal protein S12, bacterial-type; IMG reference gene:2504921221; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle; 30S ribosomal protein S12 2703600 10580833 Trebr_2299 Treponema brennaborense DSM 12168 30S ribosomal protein S12 YP_004440839.1 2703226 R 906968 CDS YP_004440840.1 332298918 10580834 complement(2703762..2708003) 1 NC_015500.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; HAMAP: DNA-directed RNA polymerase subunit beta'; InterProIPR006592:IPR007080:IPR000722:IPR007066:IPR 007083:IPR007081:IPR012754; KEGG: tpp:TPASS_0242 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; SMART: RNA polymerase, N-terminal; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime; IMG reference gene:2504921222; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form; DNA-directed RNA polymerase subunit beta' 2708003 10580834 Trebr_2300 Treponema brennaborense DSM 12168 DNA-directed RNA polymerase subunit beta' YP_004440840.1 2703762 R 906968 CDS YP_004440841.1 332298919 10580835 complement(2708084..2711605) 1 NC_015500.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; HAMAP: DNA-directed RNA polymerase subunit beta; InterProIPR007644:IPR007642:IPR007645:IPR019462:IPR 007120:IPR007641:IPR010243; KEGG: tde:TDE2421 DNA-directed RNA polymerase subunit beta; PFAM: DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 3; RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2, domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit, bacterial-type; IMG reference gene:2504921223; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit; DNA-directed RNA polymerase subunit beta 2711605 10580835 Trebr_2301 Treponema brennaborense DSM 12168 DNA-directed RNA polymerase subunit beta YP_004440841.1 2708084 R 906968 CDS YP_004440842.1 332298920 10580836 complement(2711765..2712145) 1 NC_015500.1 COGs: COG0222 Ribosomal protein L7/L12; HAMAP: Ribosomal protein L7/L12; InterPro IPR000206:IPR013823; KEGG: emi:Emin_1429 ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12, C-terminal; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: Ribosomal protein L7/L12; IMG reference gene:2504921224; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12; 50S ribosomal protein L7/L12 2712145 10580836 Trebr_2302 Treponema brennaborense DSM 12168 50S ribosomal protein L7/L12 YP_004440842.1 2711765 R 906968 CDS YP_004440843.1 332298921 10580837 complement(2712262..2712783) 1 NC_015500.1 COGs: COG0244 Ribosomal protein L10; HAMAP: 50S ribosomal protein L10; InterPro IPR001790; KEGG: tde:TDE2423 50S ribosomal protein L10; PFAM: Ribosomal protein L10; SPTR: 50S ribosomal protein L10; IMG reference gene:2504921225; PFAM: Ribosomal protein L10; 50S ribosomal protein L10 2712783 10580837 Trebr_2303 Treponema brennaborense DSM 12168 50S ribosomal protein L10 YP_004440843.1 2712262 R 906968 CDS YP_004440844.1 332298922 10580838 complement(2712786..2713466) 1 NC_015500.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR002143:IPR005878; KEGG: tde:TDE2424 50S ribosomal protein L1; PFAM: Ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: Ribosomal protein L1, bacterial-type; IMG reference gene:2504921226; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast; 50S ribosomal protein L1 2713466 10580838 Trebr_2304 Treponema brennaborense DSM 12168 50S ribosomal protein L1 YP_004440844.1 2712786 R 906968 CDS YP_004440845.1 332298923 10580839 complement(2713468..2713899) 1 NC_015500.1 COGs: COG0080 Ribosomal protein L11; InterPro IPR000911:IPR020784:IPR020783:IPR006519; KEGG: tde:TDE2425 50S ribosomal protein L11; PFAM: Ribosomal protein L11, C-terminal; Ribosomal protein L11, N-terminal; SMART: Ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: Ribosomal protein L11, bacterial-type; IMG reference gene:2504921227; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11; 50S ribosomal protein L11 2713899 10580839 Trebr_2305 Treponema brennaborense DSM 12168 50S ribosomal protein L11 YP_004440845.1 2713468 R 906968 CDS YP_004440846.1 332298924 10580840 complement(2714048..2714605) 1 NC_015500.1 COGs: COG0250 Transcription antiterminator; InterPro IPR006645:IPR005824:IPR001062; KEGG: ssm:Spirs_0944 NusG antitermination factor; PFAM: Transcription antitermination protein, NusG, N-terminal; KOW; SMART: Transcription antitermination protein, NusG, N-terminal; KOW; SPTR: Transcription antitermination protein nusG; TIGRFAM: Transcription antitermination protein, NusG; IMG reference gene:2504921228; PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG; NusG antitermination factor 2714605 10580840 Trebr_2306 Treponema brennaborense DSM 12168 NusG antitermination factor YP_004440846.1 2714048 R 906968 CDS YP_004440847.1 332298925 10580841 complement(2714619..2714798) 1 NC_015500.1 InterPro IPR001901:IPR005807; KEGG: ssm:Spirs_0943 preprotein translocase, SecE subunit; PFAM: Protein secE/sec61-gamma protein; SPTR: Preprotein translocase, SecE subunit; TIGRFAM: SecE subunit of protein translocation complex; IMG reference gene:2504921229; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial; Preprotein translocase subunit SecE 2714798 10580841 Trebr_2307 Treponema brennaborense DSM 12168 Preprotein translocase subunit SecE YP_004440847.1 2714619 R 906968 CDS YP_004440848.1 332298926 10580843 complement(2714930..2715103) 1 NC_015500.1 HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: tde:TDE2428 50S ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; IMG reference gene:2504921231; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; 50S ribosomal protein L33 2715103 10580843 Trebr_2308 Treponema brennaborense DSM 12168 50S ribosomal protein L33 YP_004440848.1 2714930 R 906968 CDS YP_004440849.1 332298927 10580845 2715433..2716281 1 NC_015500.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: sta:STHERM_c02440 serine acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; IMG reference gene:2504921233; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; Serine O-acetyltransferase 2716281 10580845 Trebr_2309 Treponema brennaborense DSM 12168 Serine O-acetyltransferase YP_004440849.1 2715433 D 906968 CDS YP_004440850.1 332298928 10580846 complement(2716310..2717548) 1 NC_015500.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: dvm:DvMF_2928 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Methicillin resistance protein; IMG reference gene:2504921234; PFAM: FemAB family; Methicillin resistance protein 2717548 10580846 Trebr_2310 Treponema brennaborense DSM 12168 Methicillin resistance protein YP_004440850.1 2716310 R 906968 CDS YP_004440851.1 332298929 10580847 2717997..2718242 1 NC_015500.1 KEGG: dma:DMR_03540 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921235; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; hypothetical protein 2718242 10580847 Trebr_2311 Treponema brennaborense DSM 12168 hypothetical protein YP_004440851.1 2717997 D 906968 CDS YP_004440852.1 332298930 10580848 2718239..2719993 1 NC_015500.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR007202; KEGG: sta:STHERM_c12360 hypothetical protein; PFAM: Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Fe-S PAS/PAC sensor protein; IMG reference gene:2504921236; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; Fe-S cluster domain-containing protein 2719993 10580848 Trebr_2312 Treponema brennaborense DSM 12168 Fe-S cluster domain-containing protein YP_004440852.1 2718239 D 906968 CDS YP_004440853.1 332298931 10580849 2719990..2721228 1 NC_015500.1 InterPro IPR010822; KEGG: sta:STHERM_c12350 hypothetical protein; PFAM: Sporulation stage II, protein E C-terminal; SPTR: stage II sporulation E family protein; IMG reference gene:2504921237; PFAM: Stage II sporulation protein E (SpoIIE); Stage II sporulation protein E 2721228 10580849 Trebr_2313 Treponema brennaborense DSM 12168 Stage II sporulation protein E YP_004440853.1 2719990 D 906968 CDS YP_004440854.1 332298932 10580850 2721420..2721674 1 NC_015500.1 KEGG: sta:STHERM_c12340 hypothetical protein; SPTR: Hydrogenase large subunit; IMG reference gene:2504921238; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; hypothetical protein 2721674 10580850 Trebr_2314 Treponema brennaborense DSM 12168 hypothetical protein YP_004440854.1 2721420 D 906968 CDS YP_004440855.1 332298933 10580851 2721812..2723287 1 NC_015500.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR004108; KEGG: tde:TDE1277 Fe-hydrogenase large subunit family protein; PFAM: Iron hydrogenase, large subunit, C-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; PRIAM: Ferredoxin hydrogenase; SPTR: Fe-hydrogenase large subunit family protein; IMG reference gene:2504921239; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; ferredoxin hydrogenase 2723287 10580851 Trebr_2315 Treponema brennaborense DSM 12168 ferredoxin hydrogenase YP_004440855.1 2721812 D 906968 CDS YP_004440856.1 332298934 10580852 2723594..2726269 1 NC_015500.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: tde:TDE0173 FtsK/SpoIIIE family protein; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase, AAA+ type, core; SPTR: DNA translocase ftsk; IMG reference gene:2504921240; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; cell division protein FtsK/SpoIIIE 2726269 10580852 Trebr_2316 Treponema brennaborense DSM 12168 cell division protein FtsK/SpoIIIE YP_004440856.1 2723594 D 906968 CDS YP_004440857.1 332298935 10580853 complement(2727405..2728634) 1 NC_015500.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; KEGG: tde:TDE1111 transporter, SPTR: Transporter, ; IMG reference gene:2504921241; PFAM: Sodium:dicarboxylate symporter family; transporter 2728634 10580853 Trebr_2317 Treponema brennaborense DSM 12168 transporter YP_004440857.1 2727405 R 906968 CDS YP_004440858.1 332298936 10580854 complement(2728825..2729817) 1 NC_015500.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: auxin efflux carrier; PFAM: Auxin efflux carrier; SPTR: Auxin Efflux Carrier; IMG reference gene:2504921242; PFAM: Membrane transport protein; auxin efflux carrier family protein 2729817 10580854 Trebr_2318 Treponema brennaborense DSM 12168 auxin efflux carrier family protein YP_004440858.1 2728825 R 906968 CDS YP_004440859.1 332298937 10580855 complement(2729858..2732641) 1 NC_015500.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR002772:IPR001764; KEGG: eat:EAT1b_1776 glycoside hydrolase family 3 domain protein; PFAM: Glycoside hydrolase, family 3, N-terminal; Glycoside hydrolase, family 3, C-terminal; PRIAM: Beta-glucosidase; SPTR: Beta-glucosidase-related glycosidases; IMG reference gene:2504921243; PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain; Beta-glucosidase 2732641 10580855 Trebr_2319 Treponema brennaborense DSM 12168 Beta-glucosidase YP_004440859.1 2729858 R 906968 CDS YP_004440860.1 332298938 10580856 2732931..2734073 1 NC_015500.1 KEGG: hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921244; hypothetical protein 2734073 10580856 Trebr_2320 Treponema brennaborense DSM 12168 hypothetical protein YP_004440860.1 2732931 D 906968 CDS YP_004440861.1 332298939 10580857 complement(2734142..2734783) 1 NC_015500.1 COGs: COG0450 Peroxiredoxin; HAMAP: peroxiredoxin; InterPro IPR000866:IPR019479; KEGG: drt:Dret_2393 peroxiredoxin; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin, C-terminal; PRIAM: Peroxiredoxin; SPTR: Probable peroxiredoxin; IMG reference gene:2504921245; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; peroxiredoxin 2734783 10580857 Trebr_2321 Treponema brennaborense DSM 12168 peroxiredoxin YP_004440861.1 2734142 R 906968 CDS YP_004440862.1 332298940 10580858 complement(2734994..2735572) 1 NC_015500.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR008332:IPR014048; KEGG: amu:Amuc_0725 methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; Methylguanine DNA methyltransferase, ribonuclease-like; SPTR: Methylated-DNA-[protein]-cysteine S-methyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504921246; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase 2735572 10580858 Trebr_2322 Treponema brennaborense DSM 12168 methylated-DNA--protein-cysteine methyltransferase YP_004440862.1 2734994 R 906968 CDS YP_004440863.1 332298941 10580859 complement(2735617..2736531) 1 NC_015500.1 COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: cbe:Cbei_1305 lysophospholipase; PFAM: Alpha/beta hydrolase fold-1; SPTR: hydrolase, alpha/beta hydrolase fold family; IMG reference gene:2504921247; PFAM: lysophospholipase; alpha/beta hydrolase fold protein 2736531 10580859 Trebr_2323 Treponema brennaborense DSM 12168 alpha/beta hydrolase fold protein YP_004440863.1 2735617 R 906968 CDS YP_004440864.1 332298942 10580860 2736731..2737591 1 NC_015500.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: tde:TDE0408 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD/NAD(P)-binding; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin--NADP; IMG reference gene:2504921248; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; oxidoreductase FAD/NAD(P)-binding domain-containing protein 2737591 10580860 Trebr_2324 Treponema brennaborense DSM 12168 oxidoreductase FAD/NAD(P)-binding domain-containing protein YP_004440864.1 2736731 D 906968 CDS YP_004440865.1 332298943 10580861 2737588..2739087 1 NC_015500.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: tde:TDE0407 oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric; IMG reference gene:2504921249; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; glutamate synthase (NADPH), homotetrameric 2739087 10580861 Trebr_2325 Treponema brennaborense DSM 12168 glutamate synthase (NADPH), homotetrameric YP_004440865.1 2737588 D 906968 CDS YP_004440866.1 332298944 10580862 complement(2739396..2741303) 1 NC_015500.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tde:TDE1742 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase., o-succinylbenzoate--CoA ligase; SPTR: AMP-binding enzyme family protein; IMG reference gene:2504921250; PFAM: AMP-binding enzyme; o-succinylbenzoate--CoA ligase 2741303 10580862 Trebr_2326 Treponema brennaborense DSM 12168 o-succinylbenzoate--CoA ligase YP_004440866.1 2739396 R 906968 CDS YP_004440867.1 332298945 10580863 complement(2741461..2743017) 1 NC_015500.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain; InterPro IPR002319:IPR004529; KEGG: tde:TDE0109 phenylalanyl-tRNA synthetase subunit alpha; PFAM: Phenylalanyl-tRNA synthetase alpha chain; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504921251; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 2743017 10580863 Trebr_2327 Treponema brennaborense DSM 12168 phenylalanyl-tRNA synthetase subunit alpha YP_004440867.1 2741461 R 906968 CDS YP_004440868.1 332298946 10580864 complement(2743030..2743398) 1 NC_015500.1 IMG reference gene:2504921252; hypothetical protein 2743398 10580864 Trebr_2328 Treponema brennaborense DSM 12168 hypothetical protein YP_004440868.1 2743030 R 906968 CDS YP_004440869.1 332298947 10580865 complement(2743482..2744180) 1 NC_015500.1 KEGG: tde:TDE0123 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921253; hypothetical protein 2744180 10580865 Trebr_2329 Treponema brennaborense DSM 12168 hypothetical protein YP_004440869.1 2743482 R 906968 CDS YP_004440870.1 332298948 10580866 complement(2744156..2744797) 1 NC_015500.1 COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: sta:STHERM_c21730 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein; IMG reference gene:2504921254; PFAM: Rhomboid family; rhomboid family protein 2744797 10580866 Trebr_2330 Treponema brennaborense DSM 12168 rhomboid family protein YP_004440870.1 2744156 R 906968 CDS YP_004440871.1 332298949 10580867 complement(2744834..2745961) 1 NC_015500.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: tde:TDE0125 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504921255; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 2745961 10580867 Trebr_2331 Treponema brennaborense DSM 12168 diguanylate cyclase YP_004440871.1 2744834 R 906968 CDS YP_004440872.1 332298950 10580868 complement(2745961..2747541) 1 NC_015500.1 KEGG: tde:TDE0126 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921256; hypothetical protein 2747541 10580868 Trebr_2332 Treponema brennaborense DSM 12168 hypothetical protein YP_004440872.1 2745961 R 906968 CDS YP_004440873.1 332298951 10580869 complement(2747601..2750465) 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: tde:TDE0932 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase catalytic domain protein; IMG reference gene:2504921257; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; adenylate/guanylate cyclase with Chase sensor 2750465 10580869 Trebr_2333 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase with Chase sensor YP_004440873.1 2747601 R 906968 CDS YP_004440874.1 332298952 10580870 2750702..2752255 1 NC_015500.1 IMG reference gene:2504921258; hypothetical protein 2752255 10580870 Trebr_2334 Treponema brennaborense DSM 12168 hypothetical protein YP_004440874.1 2750702 D 906968 CDS YP_004440875.1 332298953 10580871 2752299..2752769 1 NC_015500.1 KEGG: tde:TDE1328 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921259; hypothetical protein 2752769 10580871 Trebr_2335 Treponema brennaborense DSM 12168 hypothetical protein YP_004440875.1 2752299 D 906968 CDS YP_004440876.1 332298954 10580872 2752766..2753869 1 NC_015500.1 KEGG: tde:TDE1327 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921260; hypothetical protein 2753869 10580872 Trebr_2336 Treponema brennaborense DSM 12168 hypothetical protein YP_004440876.1 2752766 D 906968 CDS YP_004440877.1 332298955 10580873 2753879..2754589 1 NC_015500.1 KEGG: tde:TDE1324 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921261; PFAM: FecR protein; hypothetical protein 2754589 10580873 Trebr_2337 Treponema brennaborense DSM 12168 hypothetical protein YP_004440877.1 2753879 D 906968 CDS YP_004440878.1 332298956 10580874 complement(2754582..2755676) 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: tde:TDE2241 glycosyl transferase, group 2 family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504921262; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2755676 10580874 Trebr_2338 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004440878.1 2754582 R 906968 CDS YP_004440879.1 332298957 10580875 complement(2755710..2756936) 1 NC_015500.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR004652; KEGG: tde:TDE2731 NifR3 family TIM-barrel protein; PFAM: tRNA-dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, NifR3; IMG reference gene:2504921263; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, nifR3 family; nifR3 family TIM-barrel protein 2756936 10580875 Trebr_2339 Treponema brennaborense DSM 12168 nifR3 family TIM-barrel protein YP_004440879.1 2755710 R 906968 CDS YP_004440880.1 332298958 10580876 complement(2756945..2757718) 1 NC_015500.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130:IPR015991; KEGG: tde:TDE2730 TatD family hydrolase; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504921264; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; TatD family hydrolase 2757718 10580876 Trebr_2340 Treponema brennaborense DSM 12168 TatD family hydrolase YP_004440880.1 2756945 R 906968 CDS YP_004440881.1 332298959 10580877 2758007..2759029 1 NC_015500.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tde:TDE0110 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2504921265; PFAM: Peptidase family M23; peptidase M23 2759029 10580877 Trebr_2341 Treponema brennaborense DSM 12168 peptidase M23 YP_004440881.1 2758007 D 906968 CDS YP_004440882.1 332298960 10580878 2759040..2759480 1 NC_015500.1 COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tde:TDE0111 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: uncharacterized protein; IMG reference gene:2504921266; PFAM: Protein of unknown function, DUF583; hypothetical protein 2759480 10580878 Trebr_2342 Treponema brennaborense DSM 12168 hypothetical protein YP_004440882.1 2759040 D 906968 CDS YP_004440883.1 332298961 10580879 2759467..2760000 1 NC_015500.1 COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: tde:TDE0112 hypothetical protein; PFAM: Protein of unknown function DUF327; SPTR: uncharacterized protein; IMG reference gene:2504921267; PFAM: Protein of unknown function (DUF327); hypothetical protein 2760000 10580879 Trebr_2343 Treponema brennaborense DSM 12168 hypothetical protein YP_004440883.1 2759467 D 906968 CDS YP_004440884.1 332298962 10580880 2760024..2760956 1 NC_015500.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: tde:TDE0113 tpl protein; PFAM: PSP1, C-terminal; SPTR: Tpl protein; IMG reference gene:2504921268; PFAM: PSP1 C-terminal conserved region; PSP1 domain-containing protein 2760956 10580880 Trebr_2344 Treponema brennaborense DSM 12168 PSP1 domain-containing protein YP_004440884.1 2760024 D 906968 CDS YP_004440885.1 332298963 10580881 complement(2761054..2761788) 1 NC_015500.1 KEGG: cce:Ccel_1149 methyltransferase type 11; SPTR: Methyltransferase type 11; IMG reference gene:2504921269; PFAM: Methyltransferase domain; hypothetical protein 2761788 10580881 Trebr_2345 Treponema brennaborense DSM 12168 hypothetical protein YP_004440885.1 2761054 R 906968 CDS YP_004440886.1 332298964 10580882 complement(2761910..2762938) 1 NC_015500.1 IMG reference gene:2504921270; hypothetical protein 2762938 10580882 Trebr_2346 Treponema brennaborense DSM 12168 hypothetical protein YP_004440886.1 2761910 R 906968 CDS YP_004440887.1 332298965 10580883 2763168..2764565 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: tde:TDE2475 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; IMG reference gene:2504921271; PFAM: MatE; TIGRFAM: efflux protein, MATE family; multi antimicrobial extrusion protein MatE 2764565 10580883 Trebr_2347 Treponema brennaborense DSM 12168 multi antimicrobial extrusion protein MatE YP_004440887.1 2763168 D 906968 CDS YP_004440888.1 332298966 10580884 complement(2764685..2765812) 1 NC_015500.1 InterPro IPR002575; KEGG: amu:Amuc_0030 hypothetical protein; PFAM: Aminoglycoside phosphotransferase; SPTR: uncharacterized protein; IMG reference gene:2504921272; PFAM: Phosphotransferase enzyme family; aminoglycoside phosphotransferase 2765812 10580884 Trebr_2348 Treponema brennaborense DSM 12168 aminoglycoside phosphotransferase YP_004440888.1 2764685 R 906968 CDS YP_004440889.1 332298967 10580885 complement(2765871..2766818) 1 NC_015500.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: ere:EUBREC_0132 Ada regulatory protein/6-O-methylguanine-DNA methyltransferase; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; IMG reference gene:2504921273; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; AraC family transcriptional regulator 2766818 10580885 Trebr_2349 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004440889.1 2765871 R 906968 CDS YP_004440890.1 332298968 10580886 2766977..2768359 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: bcq:BCQ_1985 YvdG; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; TIGRFAM: carbohydrate ABC transporter substrate-binding protein, CPR_0540 family; IMG reference gene:2504921274; TIGRFAM: carbohydrate ABC transporter substrate-binding protein, CPR_0540 family; carbohydrate ABC transporter substrate-binding protein 2768359 10580886 Trebr_2350 Treponema brennaborense DSM 12168 carbohydrate ABC transporter substrate-binding protein YP_004440890.1 2766977 D 906968 CDS YP_004440891.1 332298969 10580887 2768497..2769399 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: apr:Apre_1667 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Transmembrane permease MsmF; IMG reference gene:2504921275; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2769399 10580887 Trebr_2351 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440891.1 2768497 D 906968 CDS YP_004440892.1 332298970 10580888 2769413..2770321 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_0575 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family (TC 3.A.1.1.-); IMG reference gene:2504921276; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2770321 10580888 Trebr_2352 Treponema brennaborense DSM 12168 ABC transporter permease YP_004440892.1 2769413 D 906968 CDS YP_004440893.1 332298971 10580889 2770467..2772626 1 NC_015500.1 InterPro IPR012711; KEGG: ere:EUBREC_0138 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921277; PFAM: Lacto-N-biose phosphorylase; TIGRFAM: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; hypothetical protein 2772626 10580889 Trebr_2353 Treponema brennaborense DSM 12168 hypothetical protein YP_004440893.1 2770467 D 906968 CDS YP_004440894.1 332298972 10580890 2772802..2774001 1 NC_015500.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: csh:Closa_1923 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504921278; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic sulfatase-maturating enzyme; radical SAM additional 4Fe4S-binding domain; Radical SAM domain protein 2774001 10580890 Trebr_2354 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004440894.1 2772802 D 906968 CDS YP_004440895.1 332298973 10580891 complement(2774010..2775470) 1 NC_015500.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: cpf:CPF_0221 arylsulfatase; PFAM: Sulfatase; SPTR: Arylsulfatase; IMG reference gene:2504921279; PFAM: Sulfatase; sulfatase 2775470 10580891 Trebr_2355 Treponema brennaborense DSM 12168 sulfatase YP_004440895.1 2774010 R 906968 CDS YP_004440896.1 332298974 10580892 2775613..2776728 1 NC_015500.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: gym:GYMC10_1924 peptidase M29 aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; IMG reference gene:2504921280; PFAM: Thermophilic metalloprotease (M29); peptidase M29 aminopeptidase II 2776728 10580892 Trebr_2356 Treponema brennaborense DSM 12168 peptidase M29 aminopeptidase II YP_004440896.1 2775613 D 906968 CDS YP_004440897.1 332298975 10580893 complement(2776745..2778289) 1 NC_015500.1 KEGG: tde:TDE0081 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921281; PFAM: Mitochondrial small ribosomal subunit Rsm22; hypothetical protein 2778289 10580893 Trebr_2357 Treponema brennaborense DSM 12168 hypothetical protein YP_004440897.1 2776745 R 906968 CDS YP_004440898.1 332298976 10580894 complement(2778286..2778669) 1 NC_015500.1 InterPro IPR000551; KEGG: tde:TDE0082 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator, MerR family; IMG reference gene:2504921282; PFAM: MerR family regulatory protein; regulatory protein MerR 2778669 10580894 Trebr_2358 Treponema brennaborense DSM 12168 regulatory protein MerR YP_004440898.1 2778286 R 906968 CDS YP_004440899.1 332298977 10580895 complement(2778645..2780138) 1 NC_015500.1 COGs: COG1160 GTPase; HAMAP: GTP-binding, EngA; InterPro IPR016484:IPR002917:IPR005225; KEGG: tde:TDE0083 GTP-binding protein EngA; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: GTP-binding, EngA; Small GTP-binding protein; IMG reference gene:2504921283; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain; GTP-binding protein engA 2780138 10580895 Trebr_2359 Treponema brennaborense DSM 12168 GTP-binding protein engA YP_004440899.1 2778645 R 906968 CDS YP_004440900.1 332298978 10580896 complement(2780241..2781944) 1 NC_015500.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR008731:IPR008279:IPR000121:IPR006318; KEGG: sta:STHERM_c12990 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile region; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SPTR: Phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; IMG reference gene:2504921284; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; phosphoenolpyruvate-protein phosphotransferase 2781944 10580896 Trebr_2360 Treponema brennaborense DSM 12168 phosphoenolpyruvate-protein phosphotransferase YP_004440900.1 2780241 R 906968 CDS YP_004440901.1 332298979 10580897 2782109..2783404 1 NC_015500.1 COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR002496:IPR008179; KEGG: kko:Kkor_0859 phosphoribosyl-ATP diphosphatase; PFAM: Histidine biosynthesis; Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504921285; PFAM: Histidine biosynthesis protein; Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-ATP diphosphatase 2783404 10580897 Trebr_2361 Treponema brennaborense DSM 12168 phosphoribosyl-ATP diphosphatase YP_004440901.1 2782109 D 906968 CDS YP_004440902.1 332298980 10580898 2783414..2784733 1 NC_015500.1 COGs: COG0141 Histidinol dehydrogenase; HAMAP: Histidinol dehydrogenase, prokaryotic-type; InterPro IPR012131; KEGG: eba:ebA1299 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase, prokaryotic-type; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type; IMG reference gene:2504921286; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; histidinol dehydrogenase 2784733 10580898 Trebr_2362 Treponema brennaborense DSM 12168 histidinol dehydrogenase YP_004440902.1 2783414 D 906968 CDS YP_004440903.1 332298981 10580899 complement(2784728..2785681) 1 NC_015500.1 InterPro IPR002123; KEGG: tde:TDE2222 hypothetical protein; SMART: Phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; IMG reference gene:2504921287; PFAM: Acyltransferase; phospholipid/glycerol acyltransferase 2785681 10580899 Trebr_2363 Treponema brennaborense DSM 12168 phospholipid/glycerol acyltransferase YP_004440903.1 2784728 R 906968 CDS YP_004440904.1 332298982 10580900 2785694..2786917 1 NC_015500.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: tde:TDE0336 hypothetical protein; PFAM: Uncharacterised protein family UPF0118; SPTR: Membrane protein, ; IMG reference gene:2504921288; PFAM: Domain of unknown function DUF20; hypothetical protein 2786917 10580900 Trebr_2364 Treponema brennaborense DSM 12168 hypothetical protein YP_004440904.1 2785694 D 906968 CDS YP_004440905.1 332298983 10580901 2786922..2788643 1 NC_015500.1 COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: hfe:Hfelis_13380 integral membrane protein; PFAM: YjeF-related protein, N-terminal; Uncharacterised protein family, carbohydrate kinase-related; SPTR: Integral membrane protein; TIGRFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal; IMG reference gene:2504921289; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related; yjeF N-terminal region; hypothetical protein 2788643 10580901 Trebr_2365 Treponema brennaborense DSM 12168 hypothetical protein YP_004440905.1 2786922 D 906968 CDS YP_004440906.1 332298984 10580902 complement(2788640..2789119) 1 NC_015500.1 COGs: COG1854 LuxS protein involved in autoinducer AI2 synthesis; HAMAP: S-ribosylhomocysteinase (LuxS); InterPro IPR003815; KEGG: bpb:bpr_I0033 S-ribosylhomocysteinase LuxS; PFAM: S-ribosylhomocysteinase (LuxS); PRIAM: S-ribosylhomocysteine lyase; SPTR: S-ribosylhomocysteine lyase; IMG reference gene:2504921290; PFAM: S-Ribosylhomocysteinase (LuxS); quorum-sensing autoinducer 2 (AI-2), LuxS 2789119 10580902 Trebr_2366 Treponema brennaborense DSM 12168 quorum-sensing autoinducer 2 (AI-2), LuxS YP_004440906.1 2788640 R 906968 CDS YP_004440907.1 332298985 10580903 2789457..2790692 1 NC_015500.1 COGs: COG0153 Galactokinase; HAMAP: Galactokinase; InterPro IPR019539:IPR006204:IPR013750:IPR000705; KEGG: tde:TDE2212 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase, C-terminal; PRIAM: Galactokinase; SPTR: Galactokinase; TIGRFAM: Galactokinase; IMG reference gene:2504921291; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Galactokinase 2790692 10580903 Trebr_2367 Treponema brennaborense DSM 12168 Galactokinase YP_004440907.1 2789457 D 906968 CDS YP_004440908.1 332298986 10580904 2790714..2792219 1 NC_015500.1 COGs: COG4468 Galactose-1-phosphate uridyltransferase; HAMAP: Galactose-1-phosphate uridylyltransferase; InterPro IPR005849:IPR005850:IPR000766; KEGG: bpb:bpr_I2842 galactose-1-phosphate uridylyltransferase GalT; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal; Galactose-1-phosphate uridyl transferase, N-terminal; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class II; IMG reference gene:2504921292; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 2; Galactose-1-phosphate uridylyltransferase 2792219 10580904 Trebr_2368 Treponema brennaborense DSM 12168 Galactose-1-phosphate uridylyltransferase YP_004440908.1 2790714 D 906968 CDS YP_004440909.1 332298987 10580905 complement(2792203..2792655) 1 NC_015500.1 InterPro IPR000086; KEGG: ere:EUBREC_0171 mutator MutT protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; IMG reference gene:2504921293; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein; NUDIX hydrolase 2792655 10580905 Trebr_2369 Treponema brennaborense DSM 12168 NUDIX hydrolase YP_004440909.1 2792203 R 906968 CDS YP_004440910.1 332298988 10580906 complement(2792829..2796389) 1 NC_015500.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002880:IPR019752:IPR019456:IPR001450:IPR 011766:IPR011895; KEGG: tde:TDE0665 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; IMG reference gene:2504921294; PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; pyruvate ferredoxin/flavodoxin oxidoreductase 2796389 10580906 Trebr_2370 Treponema brennaborense DSM 12168 pyruvate ferredoxin/flavodoxin oxidoreductase YP_004440910.1 2792829 R 906968 CDS YP_004440911.1 332298989 10580907 2796600..2799029 1 NC_015500.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ssm:Spirs_3807 patatin; PFAM: Patatin; SPTR: Patatin; IMG reference gene:2504921295; PFAM: Patatin-like phospholipase; Surface antigen; patatin 2799029 10580907 Trebr_2371 Treponema brennaborense DSM 12168 patatin YP_004440911.1 2796600 D 906968 CDS YP_004440912.1 332298990 10580908 2799067..2799972 1 NC_015500.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: mil:ML5_0340 abc transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504921296; PFAM: ABC transporter; ABC transporter 2799972 10580908 Trebr_2372 Treponema brennaborense DSM 12168 ABC transporter YP_004440912.1 2799067 D 906968 CDS YP_004440913.1 332298991 10580909 complement(2800001..2800366) 1 NC_015500.1 IMG reference gene:2504921297; hypothetical protein 2800366 10580909 Trebr_2373 Treponema brennaborense DSM 12168 hypothetical protein YP_004440913.1 2800001 R 906968 CDS YP_004440914.1 332298992 10580910 complement(2800376..2802130) 1 NC_015500.1 InterPro IPR019501; KEGG: sta:STHERM_c19210 hypothetical protein; PFAM: Peptidase M30, hyicolysin; SPTR: uncharacterized protein; IMG reference gene:2504921298; PFAM: Peptidase M30; Peptidase M30, hyicolysin 2802130 10580910 Trebr_2374 Treponema brennaborense DSM 12168 Peptidase M30, hyicolysin YP_004440914.1 2800376 R 906968 CDS YP_004440915.1 332298993 10580911 2802196..2802969 1 NC_015500.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: ssm:Spirs_4109 protein of unknown function DUF558; PFAM: Ribosomal RNA small subunit methyltransferase E; SPTR: uncharacterized protein; TIGRFAM: Ribosomal RNA small subunit methyltransferase E; IMG reference gene:2504921299; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family; Ribosomal RNA small subunit methyltransferase E 2802969 10580911 Trebr_2375 Treponema brennaborense DSM 12168 Ribosomal RNA small subunit methyltransferase E YP_004440915.1 2802196 D 906968 CDS YP_004440916.1 332298994 10580912 2802988..2803791 1 NC_015500.1 KEGG: tde:TDE0304 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921300; hypothetical protein 2803791 10580912 Trebr_2376 Treponema brennaborense DSM 12168 hypothetical protein YP_004440916.1 2802988 D 906968 CDS YP_004440917.1 332298995 10580913 2803778..2804698 1 NC_015500.1 KEGG: dre:798921 si:ch211-217k17.9; SPTR: uncharacterized protein; IMG reference gene:2504921301; hypothetical protein 2804698 10580913 Trebr_2377 Treponema brennaborense DSM 12168 hypothetical protein YP_004440917.1 2803778 D 906968 CDS YP_004440918.1 332298996 10580914 2804745..2805332 1 NC_015500.1 COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: sli:Slin_3298 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; IMG reference gene:2504921302; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 2805332 10580914 Trebr_2378 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004440918.1 2804745 D 906968 CDS YP_004440919.1 332298997 10580915 2805345..2806019 1 NC_015500.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; HAMAP: rRNA small subunit methyltransferase G; InterPro IPR003682; KEGG: tde:TDE2513 glucose-inhibited division protein B; PFAM: rRNA small subunit methyltransferase G; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: rRNA small subunit methyltransferase G; IMG reference gene:2504921303; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Ribosomal RNA small subunit methyltransferase G 2806019 10580915 Trebr_2379 Treponema brennaborense DSM 12168 Ribosomal RNA small subunit methyltransferase G YP_004440919.1 2805345 D 906968 CDS YP_004440920.1 332298998 10580916 complement(2806070..2807485) 1 NC_015500.1 InterPro IPR019734:IPR013105:IPR001440:IPR007560; KEGG: tpp:TPASS_0915 hypothetical protein; PFAM: Restriction endonuclease, type IV-like, Mrr; Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SPTR: TPR domain protein; IMG reference gene:2504921304; PFAM: Restriction endonuclease; Tetratricopeptide repeat; restriction endonuclease 2807485 10580916 Trebr_2380 Treponema brennaborense DSM 12168 restriction endonuclease YP_004440920.1 2806070 R 906968 CDS YP_004440921.1 332298999 10580917 2807604..2809370 1 NC_015500.1 InterPro IPR002482:IPR018392; KEGG: tde:TDE2281 LysM domain-containing protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: LysM domain protein; IMG reference gene:2504921305; PFAM: Hsp70 protein; LysM domain; peptidoglycan-binding lysin domain-containing protein 2809370 10580917 Trebr_2381 Treponema brennaborense DSM 12168 peptidoglycan-binding lysin domain-containing protein YP_004440921.1 2807604 D 906968 CDS YP_004440922.1 332299000 10580918 2809379..2811538 1 NC_015500.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: tpp:TPASS_0043 possible soluble lytic transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Soluble lytic transglycosylase, ; IMG reference gene:2504921306; PFAM: Transglycosylase SLT domain; Lytic transglycosylase catalytic 2811538 10580918 Trebr_2382 Treponema brennaborense DSM 12168 Lytic transglycosylase catalytic YP_004440922.1 2809379 D 906968 CDS YP_004440923.1 332299001 10580919 complement(2811530..2813638) 1 NC_015500.1 COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: tde:TDE0411 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: CHASE2; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase catalytic domain protein; IMG reference gene:2504921307; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; adenylate/guanylate cyclase with Chase sensor 2813638 10580919 Trebr_2383 Treponema brennaborense DSM 12168 adenylate/guanylate cyclase with Chase sensor YP_004440923.1 2811530 R 906968 CDS YP_004440924.1 332299002 10580920 complement(2813649..2814533) 1 NC_015500.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: tde:TDE0410 M48 family peptidase; PFAM: Peptidase M48, Ste24p; SPTR: Peptidase, M48 family; IMG reference gene:2504921308; PFAM: Peptidase family M48; peptidase M48 Ste24p 2814533 10580920 Trebr_2384 Treponema brennaborense DSM 12168 peptidase M48 Ste24p YP_004440924.1 2813649 R 906968 CDS YP_004440925.1 332299003 10580921 complement(2814530..2815009) 1 NC_015500.1 InterPro IPR003646; KEGG: tde:TDE0409 hypothetical protein; SMART: Bacterial SH3-like region; SPTR: uncharacterized protein; IMG reference gene:2504921309; SH3 domain-containing protein 2815009 10580921 Trebr_2385 Treponema brennaborense DSM 12168 SH3 domain-containing protein YP_004440925.1 2814530 R 906968 CDS YP_004440926.1 332299004 10580922 2815109..2816896 1 NC_015500.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR000644:IPR006153; KEGG: tde:TDE1412 sodium/hydrogen exchanger family protein; PFAM: Cation/H+ exchanger; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Sodium/hydrogen exchanger family protein; IMG reference gene:2504921310; PFAM: CBS domain; Sodium/hydrogen exchanger family; sodium/hydrogen exchanger 2816896 10580922 Trebr_2386 Treponema brennaborense DSM 12168 sodium/hydrogen exchanger YP_004440926.1 2815109 D 906968 CDS YP_004440927.1 332299005 10580923 complement(2816949..2817743) 1 NC_015500.1 InterPro IPR002781; KEGG: cpe:CPE1490 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: uncharacterized protein CPE1490; IMG reference gene:2504921311; PFAM: Sulfite exporter TauE/SafE; hypothetical protein 2817743 10580923 Trebr_2387 Treponema brennaborense DSM 12168 hypothetical protein YP_004440927.1 2816949 R 906968 CDS YP_004440928.1 332299006 10580924 complement(2818028..2819263) 1 NC_015500.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: clo:HMPREF0868_0847 phosphofructokinase; PFAM: Phosphofructokinase; SPTR: uncharacterized protein; IMG reference gene:2504921312; PFAM: Phosphofructokinase; phosphofructokinase 2819263 10580924 Trebr_2388 Treponema brennaborense DSM 12168 phosphofructokinase YP_004440928.1 2818028 R 906968 CDS YP_004440929.1 332299007 10580925 complement(2819327..2820499) 1 NC_015500.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: tmt:Tmath_0287 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; IMG reference gene:2504921313; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 2820499 10580925 Trebr_2389 Treponema brennaborense DSM 12168 N-acetylglucosamine-6-phosphate deacetylase YP_004440929.1 2819327 R 906968 CDS YP_004440930.1 332299008 10580927 complement(2820952..2821290) 1 NC_015500.1 COGs: COG3870 conserved hypothetical protein; InterPro IPR010375; KEGG: cbk:CLL_A0199 protein from nitrogen regulatory protein P-II; PFAM: Protein of unknown function DUF970; SPTR: uncharacterized protein; IMG reference gene:2504921315; PFAM: Protein of unknown function (DUF970); hypothetical protein 2821290 10580927 Trebr_2391 Treponema brennaborense DSM 12168 hypothetical protein YP_004440930.1 2820952 R 906968 CDS YP_004440931.1 332299009 10580928 complement(2821406..2822098) 1 NC_015500.1 KEGG: ssm:Spirs_1602 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921316; hypothetical protein 2822098 10580928 Trebr_2392 Treponema brennaborense DSM 12168 hypothetical protein YP_004440931.1 2821406 R 906968 CDS YP_004440932.1 332299010 10580929 complement(2822095..2822703) 1 NC_015500.1 COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: tde:TDE1926 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: heptaprenyl diphosphate synthase component I; IMG reference gene:2504921317; PFAM: Heptaprenyl diphosphate synthase component I; heptaprenyl diphosphate synthase component I 2822703 10580929 Trebr_2393 Treponema brennaborense DSM 12168 heptaprenyl diphosphate synthase component I YP_004440932.1 2822095 R 906968 CDS YP_004440933.1 332299011 10580930 2822867..2824132 1 NC_015500.1 IMG reference gene:2504921318; hypothetical protein 2824132 10580930 Trebr_2394 Treponema brennaborense DSM 12168 hypothetical protein YP_004440933.1 2822867 D 906968 CDS YP_004440934.1 332299012 10580932 complement(2824879..2825886) 1 NC_015500.1 IMG reference gene:2504921320; hypothetical protein 2825886 10580932 Trebr_2396 Treponema brennaborense DSM 12168 hypothetical protein YP_004440934.1 2824879 R 906968 CDS YP_004440935.1 332299013 10580933 complement(2825913..2826473) 1 NC_015500.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: bvu:BVU_3545 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: uncharacterized protein; IMG reference gene:2504921321; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 2826473 10580933 Trebr_2397 Treponema brennaborense DSM 12168 NADPH-dependent FMN reductase YP_004440935.1 2825913 R 906968 CDS YP_004440936.1 332299014 10580934 complement(2826470..2827111) 1 NC_015500.1 KEGG: ssm:Spirs_3341 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921322; PFAM: Predicted periplasmic protein (DUF2271); hypothetical protein 2827111 10580934 Trebr_2398 Treponema brennaborense DSM 12168 hypothetical protein YP_004440936.1 2826470 R 906968 CDS YP_004440937.1 332299015 10580935 complement(2827108..2827710) 1 NC_015500.1 COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: emi:Emin_0119 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator; IMG reference gene:2504921323; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 2827710 10580935 Trebr_2399 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004440937.1 2827108 R 906968 CDS YP_004440938.1 332299016 10580936 complement(2827896..2830337) 1 NC_015500.1 COGs: COG2183 Transcriptional accessory protein; InterPro IPR006641:IPR018974:IPR003029; KEGG: tde:TDE1012 tex protein, PFAM: Tex-like protein, N-terminal; Ribosomal protein S1, RNA binding domain; SMART: Resolvase, RNase H-like fold; SPTR: Tex protein, ; IMG reference gene:2504921324; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; Tex-like protein 2830337 10580936 Trebr_2400 Treponema brennaborense DSM 12168 Tex-like protein YP_004440938.1 2827896 R 906968 CDS YP_004440939.1 332299017 10580937 complement(2830407..2830571) 1 NC_015500.1 IMG reference gene:2504921325; hypothetical protein 2830571 10580937 Trebr_2401 Treponema brennaborense DSM 12168 hypothetical protein YP_004440939.1 2830407 R 906968 CDS YP_004440940.1 332299018 10580938 complement(2830568..2831329) 1 NC_015500.1 COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: hypothetical protein; PFAM: Protein of unknown function DUF1113; SPTR: Predicted membrane protein; IMG reference gene:2504921326; PFAM: Protein of unknown function (DUF1113); hypothetical protein 2831329 10580938 Trebr_2402 Treponema brennaborense DSM 12168 hypothetical protein YP_004440940.1 2830568 R 906968 CDS YP_004440941.1 332299019 10580939 complement(2831520..2832197) 1 NC_015500.1 IMG reference gene:2504921327; hypothetical protein 2832197 10580939 Trebr_2403 Treponema brennaborense DSM 12168 hypothetical protein YP_004440941.1 2831520 R 906968 CDS YP_004440942.1 332299020 10580940 2832343..2832741 1 NC_015500.1 KEGG: elm:ELI_0829 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921328; hypothetical protein 2832741 10580940 Trebr_2404 Treponema brennaborense DSM 12168 hypothetical protein YP_004440942.1 2832343 D 906968 CDS YP_004440943.1 332299021 10580941 2832893..2833480 1 NC_015500.1 KEGG: tde:TDE1655 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921329; hypothetical protein 2833480 10580941 Trebr_2405 Treponema brennaborense DSM 12168 hypothetical protein YP_004440943.1 2832893 D 906968 CDS YP_004440944.1 332299022 10580942 complement(2833575..2833994) 1 NC_015500.1 IMG reference gene:2504921330; hypothetical protein 2833994 10580942 Trebr_2406 Treponema brennaborense DSM 12168 hypothetical protein YP_004440944.1 2833575 R 906968 CDS YP_004440945.1 332299023 10580943 complement(2834100..2836982) 1 NC_015500.1 InterPro IPR003961:IPR013378:IPR005077; KEGG: dhd:Dhaf_0489 cell wall/surface repeat protein; PFAM: Peptidase C11, clostripain; Fibronectin, type III; Listeria/Bacterioides repeat; SMART: Fibronectin, type III; SPTR: Internalin; TIGRFAM: Listeria/Bacterioides repeat; IMG reference gene:2504921331; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); Clostripain family; Fibronectin type III domain; TIGRFAM: Listeria/Bacterioides repeat; cell wall/surface repeat protein 2836982 10580943 Trebr_2407 Treponema brennaborense DSM 12168 cell wall/surface repeat protein YP_004440945.1 2834100 R 906968 CDS YP_004440946.1 332299024 10580944 2837375..2838034 1 NC_015500.1 IMG reference gene:2504921332; hypothetical protein 2838034 10580944 Trebr_2408 Treponema brennaborense DSM 12168 hypothetical protein YP_004440946.1 2837375 D 906968 CDS YP_004440947.1 332299025 10580945 2838031..2838582 1 NC_015500.1 InterPro IPR000182; KEGG: mmp:MMP1184 N-acetyltransferase-like protein; PFAM: GCN5-related N-acetyltransferase; SPTR: N-acetyltransferase related protein; IMG reference gene:2504921333; PFAM: Acetyltransferase (GNAT) family; GCN5-related N-acetyltransferase 2838582 10580945 Trebr_2409 Treponema brennaborense DSM 12168 GCN5-related N-acetyltransferase YP_004440947.1 2838031 D 906968 CDS YP_004440948.1 332299026 10580946 2838579..2839391 1 NC_015500.1 KEGG: tde:TDE0620 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921334; hypothetical protein 2839391 10580946 Trebr_2410 Treponema brennaborense DSM 12168 hypothetical protein YP_004440948.1 2838579 D 906968 CDS YP_004440949.1 332299027 10580947 2839483..2840898 1 NC_015500.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ssm:Spirs_0789 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase; IMG reference gene:2504921335; PFAM: Aldehyde dehydrogenase family; Aldehyde Dehydrogenase 2840898 10580947 Trebr_2411 Treponema brennaborense DSM 12168 Aldehyde Dehydrogenase YP_004440949.1 2839483 D 906968 CDS YP_004440950.1 332299028 10580948 2840917..2841372 1 NC_015500.1 KEGG: tde:TDE0199 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921336; hypothetical protein 2841372 10580948 Trebr_2412 Treponema brennaborense DSM 12168 hypothetical protein YP_004440950.1 2840917 D 906968 CDS YP_004440951.1 332299029 10580949 2841469..2842329 1 NC_015500.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: tpp:TPASS_0792 flagellar filament 33 kDa core protein; PFAM: Flagellin, N-terminal; Flagellin, C-terminal; SPTR: Flagellar filament 33 kDa core protein; IMG reference gene:2504921337; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein 2842329 10580949 Trebr_2413 Treponema brennaborense DSM 12168 flagellin domain-containing protein YP_004440951.1 2841469 D 906968 CDS YP_004440952.1 332299030 10580950 complement(2842339..2842926) 1 NC_015500.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); HAMAP: Recombination protein recR; InterPro IPR006154:IPR015967:IPR006171:IPR000093; KEGG: ssm:Spirs_0086 recombination protein RecR; PFAM: Toprim domain; Zinc finger C4-type, RecR; SMART: Toprim domain, subgroup; SPTR: Recombination protein RecR; TIGRFAM: RecR protein; IMG reference gene:2504921338; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR; Recombination protein recR 2842926 10580950 Trebr_2414 Treponema brennaborense DSM 12168 Recombination protein recR YP_004440952.1 2842339 R 906968 CDS YP_004440953.1 332299031 10580951 complement(2842935..2843252) 1 NC_015500.1 COGs: COG0718 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0133; InterPro IPR004401; KEGG: aar:Acear_0031 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein TREVI0001_0080; TIGRFAM: Uncharacterised protein family UPF0133; IMG reference gene:2504921339; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family; hypothetical protein 2843252 10580951 Trebr_2415 Treponema brennaborense DSM 12168 hypothetical protein YP_004440953.1 2842935 R 906968 CDS YP_004440954.1 332299032 10580952 complement(2843249..2845267) 1 NC_015500.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR003959:IPR012763; KEGG: tde:TDE2586 DNA polymerase III subunits gamma and tau; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunit gamma/ tau; IMG reference gene:2504921340; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau; DNA polymerase III subunits gamma and tau 2845267 10580952 Trebr_2416 Treponema brennaborense DSM 12168 DNA polymerase III subunits gamma and tau YP_004440954.1 2843249 R 906968 CDS YP_004440955.1 332299033 10580953 2845413..2846054 1 NC_015500.1 IMG reference gene:2504921341; hypothetical protein 2846054 10580953 Trebr_2417 Treponema brennaborense DSM 12168 hypothetical protein YP_004440955.1 2845413 D 906968 CDS YP_004440956.1 332299034 10580954 complement(2846091..2848499) 1 NC_015500.1 COGs: COG1643 HrpA-like helicase; InterProIPR014001:IPR001650:IPR007502:IPR013689:IPR 010225; KEGG: hch:HCH_05855 ATP-dependent helicase HrpB; PFAM: RNA helicase, ATP-dependent, HrpB type, C-terminal; DNA/RNA helicase, C-terminal; Helicase-associated region; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent helicase HrpB; TIGRFAM: RNA helicase, ATP-dependent DEAH box, HrpB type; IMG reference gene:2504921342; PFAM: Helicase conserved C-terminal domain; ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB; ATP-dependent helicase HrpB 2848499 10580954 Trebr_2418 Treponema brennaborense DSM 12168 ATP-dependent helicase HrpB YP_004440956.1 2846091 R 906968 CDS YP_004440957.1 332299035 10580955 complement(2848514..2850364) 1 NC_015500.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE1386 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504921343; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2850364 10580955 Trebr_2419 Treponema brennaborense DSM 12168 methyl-accepting chemotaxis sensory transducer YP_004440957.1 2848514 R 906968 CDS YP_004440958.1 332299036 10580956 complement(2850462..2851307) 1 NC_015500.1 COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254:IPR005744; KEGG: tde:TDE2317 hemolysin III; PFAM: Hly-III related; SPTR: Hemolysin III; TIGRFAM: HylII; IMG reference gene:2504921344; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family; hemolysin III family channel protein 2851307 10580956 Trebr_2420 Treponema brennaborense DSM 12168 hemolysin III family channel protein YP_004440958.1 2850462 R 906968 CDS YP_004440959.1 332299037 10580957 complement(2851443..2852231) 1 NC_015500.1 COGs: COG0566 rRNA methylase; InterPro IPR001537:IPR004441; KEGG: tde:TDE1443 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; IMG reference gene:2504921345; PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, , group 3; TrmH family RNA methyltransferase 2852231 10580957 Trebr_2421 Treponema brennaborense DSM 12168 TrmH family RNA methyltransferase YP_004440959.1 2851443 R 906968 CDS YP_004440960.1 332299038 10580958 complement(2852221..2852721) 1 NC_015500.1 COGs: COG3012 conserved hypothetical protein; InterPro IPR004027; KEGG: geo:Geob_1085 sec-C motif domain protein; PFAM: SEC-C motif; SPTR: SEC-C motif domain protein; IMG reference gene:2504921346; PFAM: SEC-C motif; SEC-C motif domain protein 2852721 10580958 Trebr_2422 Treponema brennaborense DSM 12168 SEC-C motif domain protein YP_004440960.1 2852221 R 906968 CDS YP_004440961.1 332299039 10580959 complement(2852798..2853775) 1 NC_015500.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: ttu:TERTU_1059 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; IMG reference gene:2504921347; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 2853775 10580959 Trebr_2423 Treponema brennaborense DSM 12168 NAD-dependent epimerase/dehydratase YP_004440961.1 2852798 R 906968 CDS YP_004440962.1 332299040 10580960 complement(2853801..2855012) 1 NC_015500.1 KEGG: pmo:Pmob_0347 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921348; hypothetical protein 2855012 10580960 Trebr_2424 Treponema brennaborense DSM 12168 hypothetical protein YP_004440962.1 2853801 R 906968 CDS YP_004440963.1 332299041 10580961 complement(2855014..2857296) 1 NC_015500.1 SPTR: lipoprotein; IMG reference gene:2504921349; hypothetical protein 2857296 10580961 Trebr_2425 Treponema brennaborense DSM 12168 hypothetical protein YP_004440963.1 2855014 R 906968 CDS YP_004440964.1 332299042 10580962 2857490..2858122 1 NC_015500.1 COGs: COG4684 membrane protein; KEGG: hypothetical protein; SPTR: Membrane protein; IMG reference gene:2504921350; hypothetical protein 2858122 10580962 Trebr_2426 Treponema brennaborense DSM 12168 hypothetical protein YP_004440964.1 2857490 D 906968 CDS YP_004440965.1 332299043 10580963 2858119..2859561 1 NC_015500.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: tde:TDE0087 potassium transporter peripheral membrane component; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Trk system potassium uptake protein TrkA; IMG reference gene:2504921351; PFAM: TrkA-N domain; TrkA-C domain; TrkA-N domain-containing protein 2859561 10580963 Trebr_2427 Treponema brennaborense DSM 12168 TrkA-N domain-containing protein YP_004440965.1 2858119 D 906968 CDS YP_004440966.1 332299044 10580964 2859609..2861030 1 NC_015500.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: tde:TDE0088 trk system potassium uptake protein TrkH; PFAM: Cation transporter; SPTR: Trk system potassium uptake protein TrkH; IMG reference gene:2504921352; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family; cation transporter 2861030 10580964 Trebr_2428 Treponema brennaborense DSM 12168 cation transporter YP_004440966.1 2859609 D 906968 CDS YP_004440967.1 332299045 10580965 2861105..2862052 1 NC_015500.1 COGs: COG5523 integral membrane protein; InterPro IPR010380; KEGG: bwe:BcerKBAB4_5101 hypothetical protein; PFAM: Protein of unknown function DUF975; SPTR: Predicted integral membrane protein; IMG reference gene:2504921353; PFAM: Protein of unknown function (DUF975); hypothetical protein 2862052 10580965 Trebr_2429 Treponema brennaborense DSM 12168 hypothetical protein YP_004440967.1 2861105 D 906968 CDS YP_004440968.1 332299046 10580966 complement(2862210..2864198) 1 NC_015500.1 COGs: COG0326 Molecular chaperone HSP90 family; HAMAP: Chaperone protein htpG; InterPro IPR001404:IPR003594:IPR020576; KEGG: tde:TDE2480 heat shock protein 90; PFAM: Heat shock protein Hsp90, C-terminal; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Chaperone protein htpG; IMG reference gene:2504921354; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein; chaperone protein htpG 2864198 10580966 Trebr_2430 Treponema brennaborense DSM 12168 chaperone protein htpG YP_004440968.1 2862210 R 906968 CDS YP_004440969.1 332299047 10580967 complement(2864290..2865081) 1 NC_015500.1 IMG reference gene:2504921355; hypothetical protein 2865081 10580967 Trebr_2431 Treponema brennaborense DSM 12168 hypothetical protein YP_004440969.1 2864290 R 906968 CDS YP_004440970.1 332299048 10580968 complement(2865078..2865986) 1 NC_015500.1 COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR014033; KEGG: aac:Aaci_0321 arginase; PFAM: Ureohydrolase; PRIAM: Arginase; SPTR: Arginase; TIGRFAM: Arginase, subgroup; IMG reference gene:2504921356; PFAM: Arginase family; TIGRFAM: arginase; arginase 2865986 10580968 Trebr_2432 Treponema brennaborense DSM 12168 arginase YP_004440970.1 2865078 R 906968 CDS YP_004440971.1 332299049 10580969 complement(2866027..2867718) 1 NC_015500.1 KEGG: tde:TDE1234 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921357; hypothetical protein 2867718 10580969 Trebr_2433 Treponema brennaborense DSM 12168 hypothetical protein YP_004440971.1 2866027 R 906968 CDS YP_004440972.1 332299050 10580970 complement(2867855..2869414) 1 NC_015500.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ssm:Spirs_1043 5'-nucleotidase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: 5'-nucleotidase; IMG reference gene:2504921358; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; 5'-nucleotidase 2869414 10580970 Trebr_2434 Treponema brennaborense DSM 12168 5'-nucleotidase YP_004440972.1 2867855 R 906968 CDS YP_004440973.1 332299051 10580971 complement(2869517..2869903) 1 NC_015500.1 COGs: COG1393 Arsenate reductase and related protein glutaredoxin family; InterPro IPR006660; KEGG: ele:Elen_1470 arsenate reductase and related; PFAM: Arsenate reductase-like; SPTR: uncharacterized protein; IMG reference gene:2504921359; PFAM: ArsC family; arsenate reductase-like protein 2869903 10580971 Trebr_2435 Treponema brennaborense DSM 12168 arsenate reductase-like protein YP_004440973.1 2869517 R 906968 CDS YP_004440974.1 332299052 10580972 2870156..2871349 1 NC_015500.1 COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR000241; KEGG: tde:TDE0938 hypothetical protein; PFAM: RNA methylase; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: RNA methylase family protein; IMG reference gene:2504921360; PFAM: RNA methylase family UPF0020; rRNA (guanine-N(2)-)-methyltransferase 2871349 10580972 Trebr_2436 Treponema brennaborense DSM 12168 rRNA (guanine-N(2)-)-methyltransferase YP_004440974.1 2870156 D 906968 CDS YP_004440975.1 332299053 10580973 2871333..2871929 1 NC_015500.1 InterPro IPR001647; KEGG: lsp:Bsph_4063 YsiA; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: YsiA; IMG reference gene:2504921361; PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 2871929 10580973 Trebr_2437 Treponema brennaborense DSM 12168 TetR family transcriptional regulator YP_004440975.1 2871333 D 906968 CDS YP_004440976.1 332299054 10580974 complement(2872224..2873384) 1 NC_015500.1 KEGG: bvu:BVU_2383 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921362; hypothetical protein 2873384 10580974 Trebr_2438 Treponema brennaborense DSM 12168 hypothetical protein YP_004440976.1 2872224 R 906968 CDS YP_004440977.1 332299055 10580975 complement(2874262..2877348) 1 NC_015500.1 COGs: COG1204 Superfamily II helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: plm:Plim_1063 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase; IMG reference gene:2504921363; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase domain protein 2877348 10580975 Trebr_2439 Treponema brennaborense DSM 12168 DEAD/DEAH box helicase domain protein YP_004440977.1 2874262 R 906968 CDS YP_004440978.1 332299056 10580976 complement(2877338..2878144) 1 NC_015500.1 KEGG: plm:Plim_1064 hypothetical protein; SPTR: Virulence associated protein; IMG reference gene:2504921364; hypothetical protein 2878144 10580976 Trebr_2440 Treponema brennaborense DSM 12168 hypothetical protein YP_004440978.1 2877338 R 906968 CDS YP_004440979.1 332299057 10580977 complement(2878192..2880132) 1 NC_015500.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR000055:IPR002725; KEGG: apa:APP7_1526 restriction-modification enzyme; PFAM: Protein of unknown function DUF45; Restriction endonuclease, type I, S subunit, EcoBI; SPTR: phosphoribosylformylglycinamidine synthase; IMG reference gene:2504921365; PFAM: Protein of unknown function DUF45; Type I restriction modification DNA specificity domain; hypothetical protein 2880132 10580977 Trebr_2441 Treponema brennaborense DSM 12168 hypothetical protein YP_004440979.1 2878192 R 906968 CDS YP_004440980.1 332299058 10580978 complement(2880132..2881661) 1 NC_015500.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: hsdM; type I restriction-modification system, M subunit; PFAM: DNA methylase, adenine-specific; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: uncharacterized protein; IMG reference gene:2504921366; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; adenine-specific DNA-methyltransferase 2881661 10580978 Trebr_2442 Treponema brennaborense DSM 12168 adenine-specific DNA-methyltransferase YP_004440980.1 2880132 R 906968 CDS YP_004440981.1 332299059 10580979 complement(2881678..2884074) 1 NC_015500.1 COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR014001:IPR007409:IPR006935:IPR013670; KEGG: hor:Hore_20230 EcoEI R domain protein; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, EcoEI, R subunit/Type III, Res subunit, C-terminal; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase, N-terminal; SPTR: Type I site-specific restriction-modification system, R (Restriction) subunit and related helicases; IMG reference gene:2504921367; PFAM: Type III restriction enzyme, res subunit; EcoEI R protein C-terminal; Type I site-specific deoxyribonuclease 2884074 10580979 Trebr_2443 Treponema brennaborense DSM 12168 Type I site-specific deoxyribonuclease YP_004440981.1 2881678 R 906968 CDS YP_004440982.1 332299060 10580980 complement(2884479..2884724) 1 NC_015500.1 IMG reference gene:2504921368; hypothetical protein 2884724 10580980 Trebr_2444 Treponema brennaborense DSM 12168 hypothetical protein YP_004440982.1 2884479 R 906968 CDS YP_004440983.1 332299061 10580981 complement(2884734..2886452) 1 NC_015500.1 KEGG: ere:EUBREC_0392 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921369; hypothetical protein 2886452 10580981 Trebr_2445 Treponema brennaborense DSM 12168 hypothetical protein YP_004440983.1 2884734 R 906968 CDS YP_004440984.1 332299062 10580982 complement(2886465..2887208) 1 NC_015500.1 InterPro IPR003115; KEGG: dat:HRM2_38800 plasmid replication/partition related protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: plasmid replication/partition related protein ParB; IMG reference gene:2504921370; PFAM: ParB-like nuclease domain; ParB domain-containing protein nuclease 2887208 10580982 Trebr_2446 Treponema brennaborense DSM 12168 ParB domain-containing protein nuclease YP_004440984.1 2886465 R 906968 CDS YP_004440985.1 332299063 10580983 complement(2887283..2887978) 1 NC_015500.1 COGs: COG1484 DNA replication protein; KEGG: hha:Hhal_0638 IstB ATP binding domain-containing protein; SPTR: Phage DNA replication protein (Predicted replicative helicase loader); IMG reference gene:2504921371; PFAM: IstB-like ATP binding protein; IstB ATP binding domain-containing protein 2887978 10580983 Trebr_2447 Treponema brennaborense DSM 12168 IstB ATP binding domain-containing protein YP_004440985.1 2887283 R 906968 CDS YP_004440986.1 332299064 10580984 complement(2887990..2888694) 1 NC_015500.1 KEGG: cbt:CLH_1752 phage protein; SPTR: Phage protein; IMG reference gene:2504921372; hypothetical protein 2888694 10580984 Trebr_2448 Treponema brennaborense DSM 12168 hypothetical protein YP_004440986.1 2887990 R 906968 CDS YP_004440987.1 332299065 10580985 complement(2888675..2888881) 1 NC_015500.1 IMG reference gene:2504921373; hypothetical protein 2888881 10580985 Trebr_2449 Treponema brennaborense DSM 12168 hypothetical protein YP_004440987.1 2888675 R 906968 CDS YP_004440988.1 332299066 10580986 complement(2888878..2889102) 1 NC_015500.1 IMG reference gene:2504921374; TIGRFAM: DNA binding domain, excisionase family; hypothetical protein 2889102 10580986 Trebr_2450 Treponema brennaborense DSM 12168 hypothetical protein YP_004440988.1 2888878 R 906968 CDS YP_004440989.1 332299067 10580987 complement(2889257..2890417) 1 NC_015500.1 IMG reference gene:2504921375; hypothetical protein 2890417 10580987 Trebr_2451 Treponema brennaborense DSM 12168 hypothetical protein YP_004440989.1 2889257 R 906968 CDS YP_004440990.1 332299068 10580988 complement(2890651..2892315) 1 NC_015500.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: bbp:BBPR_0130 DNA-binding protein; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: transcriptional regulator; IMG reference gene:2504921376; PFAM: Divergent AAA domain; transcriptional regulator 2892315 10580988 Trebr_2452 Treponema brennaborense DSM 12168 transcriptional regulator YP_004440990.1 2890651 R 906968 CDS YP_004440991.1 332299069 10580989 complement(2892425..2893237) 1 NC_015500.1 InterPro IPR003115; KEGG: dat:HRM2_38800 plasmid replication/partition related protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: plasmid replication/partition related protein ParB; IMG reference gene:2504921377; PFAM: ParB-like nuclease domain; ParB domain-containing protein nuclease 2893237 10580989 Trebr_2453 Treponema brennaborense DSM 12168 ParB domain-containing protein nuclease YP_004440991.1 2892425 R 906968 CDS YP_004440992.1 332299070 10580990 complement(2893256..2894593) 1 NC_015500.1 InterPro IPR002104; KEGG: ssm:Spirs_1738 hypothetical protein; PFAM: Integrase, catalytic core, phage; SPTR: uncharacterized protein; IMG reference gene:2504921378; PFAM: Phage integrase family; integrase family protein 2894593 10580990 Trebr_2454 Treponema brennaborense DSM 12168 integrase family protein YP_004440992.1 2893256 R 906968 CDS YP_004440993.1 332299071 10580993 2895349..2895831 1 NC_015500.1 IMG reference gene:2504921381; hypothetical protein 2895831 10580993 Trebr_2455 Treponema brennaborense DSM 12168 hypothetical protein YP_004440993.1 2895349 D 906968 CDS YP_004440994.1 332299072 10580995 2896610..2896762 1 NC_015500.1 IMG reference gene:2504921383; hypothetical protein 2896762 10580995 Trebr_2457 Treponema brennaborense DSM 12168 hypothetical protein YP_004440994.1 2896610 D 906968 CDS YP_004440995.1 332299073 10580996 2896872..2900285 1 NC_015500.1 InterPro IPR006935:IPR001650:IPR014001; KEGG: kol:Kole_1972 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase domain protein; IMG reference gene:2504921384; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; helicase domain-containing protein 2900285 10580996 Trebr_2458 Treponema brennaborense DSM 12168 helicase domain-containing protein YP_004440995.1 2896872 D 906968 CDS YP_004440996.1 332299074 10580997 2900297..2901706 1 NC_015500.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: ssm:Spirs_4290 transcriptional regulator; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: transcriptional regulator; IMG reference gene:2504921385; PFAM: Divergent AAA domain; transcriptional regulator 2901706 10580997 Trebr_2459 Treponema brennaborense DSM 12168 transcriptional regulator YP_004440996.1 2900297 D 906968 CDS YP_004440997.1 332299075 10580998 2901708..2905082 1 NC_015500.1 InterPro IPR011639; KEGG: pgi:PG0862 type IIS restriction endonuclease, SPTR: type IIS restriction endonuclease; IMG reference gene:2504921386; PFAM: N-6 DNA Methylase; Eco57I restriction endonuclease; type IIS restriction endonuclease 2905082 10580998 Trebr_2460 Treponema brennaborense DSM 12168 type IIS restriction endonuclease YP_004440997.1 2901708 D 906968 CDS YP_004440998.1 332299076 10580999 complement(2905079..2905957) 1 NC_015500.1 KEGG: bfr:BF3008 type IIS restriction/modification enzyme; SPTR: Eco57I restriction endonuclease; IMG reference gene:2504921387; type IIS restriction/modification enzyme 2905957 10580999 Trebr_2461 Treponema brennaborense DSM 12168 type IIS restriction/modification enzyme YP_004440998.1 2905079 R 906968 CDS YP_004440999.1 332299077 10581000 complement(2905959..2906588) 1 NC_015500.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119; KEGG: pgi:PG0864 multiple promoter invertase; PFAM: Resolvase, N-terminal; SPTR: Site-specific recombinase, resolvase family; IMG reference gene:2504921388; PFAM: Resolvase, N terminal domain; Resolvase domain-containing protein 2906588 10581000 Trebr_2462 Treponema brennaborense DSM 12168 Resolvase domain-containing protein YP_004440999.1 2905959 R 906968 CDS YP_004441000.1 332299078 10581001 complement(2907736..2908488) 1 NC_015500.1 COGs: COG3884 Acyl-ACP thioesterase; InterPro IPR002864; KEGG: gym:GYMC10_0920 acyl-ACP thioesterase; PFAM: Acyl-ACP thioesterase; SPTR: uncharacterized protein; IMG reference gene:2504921389; PFAM: Acyl-ACP thioesterase; acyl-ACP thioesterase 2908488 10581001 Trebr_2463 Treponema brennaborense DSM 12168 acyl-ACP thioesterase YP_004441000.1 2907736 R 906968 CDS YP_004441001.1 332299079 10581002 complement(2908564..2909424) 1 NC_015500.1 InterPro IPR003538:IPR006260; KEGG: tkm:TK90_0441 TonB family protein; PFAM: Gram-negative bacterial tonB protein; SPTR: TonB family protein; TIGRFAM: TonB, C-terminal; IMG reference gene:2504921390; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TonB family protein 2909424 10581002 Trebr_2464 Treponema brennaborense DSM 12168 TonB family protein YP_004441001.1 2908564 R 906968 CDS YP_004441002.1 332299080 10581003 complement(2909442..2911457) 1 NC_015500.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: ssm:Spirs_1015 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor plug; IMG reference gene:2504921391; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TonB-dependent receptor plug 2911457 10581003 Trebr_2465 Treponema brennaborense DSM 12168 TonB-dependent receptor plug YP_004441002.1 2909442 R 906968 CDS YP_004441003.1 332299081 10581004 complement(2911707..2914295) 1 NC_015500.1 COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR003726:IPR000489:IPR003759:IPR006158; KEGG: csh:Closa_2452 homocysteine S-methyltransferase; PFAM: Cobalamin (vitamin B12)-binding; Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; PRIAM: Methionine synthase; SPTR: Homocysteine S-methyltransferase; IMG reference gene:2504921392; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; Methionine synthase 2914295 10581004 Trebr_2466 Treponema brennaborense DSM 12168 Methionine synthase YP_004441003.1 2911707 R 906968 CDS YP_004441004.1 332299082 10581005 complement(2914540..2914896) 1 NC_015500.1 InterPro IPR001387; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; IMG reference gene:2504921393; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 2914896 10581005 Trebr_2467 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004441004.1 2914540 R 906968 CDS YP_004441005.1 332299083 10581006 2915001..2915405 1 NC_015500.1 IMG reference gene:2504921394; hypothetical protein 2915405 10581006 Trebr_2468 Treponema brennaborense DSM 12168 hypothetical protein YP_004441005.1 2915001 D 906968 CDS YP_004441006.1 332299084 10581007 2915425..2916351 1 NC_015500.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: lrf:LAR_1295 glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504921395; PFAM: Glycosyl transferase family 2; family 2 glycosyl transferase 2916351 10581007 Trebr_2469 Treponema brennaborense DSM 12168 family 2 glycosyl transferase YP_004441006.1 2915425 D 906968 CDS YP_004441007.1 332299085 10581008 2916348..2917646 1 NC_015500.1 KEGG: cbk:CLL_A3245 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921396; hypothetical protein 2917646 10581008 Trebr_2470 Treponema brennaborense DSM 12168 hypothetical protein YP_004441007.1 2916348 D 906968 CDS YP_004441008.1 332299086 10581009 2918200..2918625 1 NC_015500.1 InterPro IPR019004; KEGG: nam:NAMH_0846 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921397; PFAM: Yqey-like protein; hypothetical protein 2918625 10581009 Trebr_2471 Treponema brennaborense DSM 12168 hypothetical protein YP_004441008.1 2918200 D 906968 CDS YP_004441009.1 332299087 10581010 complement(2918821..2919630) 1 NC_015500.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR010499; KEGG: mla:Mlab_0010 hypothetical protein; PFAM: HTH transcriptional regulator, MerR; Bacterial transcription activator, effector binding; SMART: HTH transcriptional regulator, MerR; SPTR: Transcription activator effector binding; IMG reference gene:2504921398; PFAM: MerR family regulatory protein; Bacterial transcription activator, effector binding domain; MerR family transcriptional regulator 2919630 10581010 Trebr_2472 Treponema brennaborense DSM 12168 MerR family transcriptional regulator YP_004441009.1 2918821 R 906968 CDS YP_004441010.1 332299088 10581011 complement(2919633..2919998) 1 NC_015500.1 KEGG: rci:RCIX1720 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921399; hypothetical protein 2919998 10581011 Trebr_2473 Treponema brennaborense DSM 12168 hypothetical protein YP_004441010.1 2919633 R 906968 CDS YP_004441011.1 332299089 10581012 complement(2920205..2920927) 1 NC_015500.1 InterPro IPR013525; KEGG: dhd:Dhaf_3151 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; IMG reference gene:2504921400; PFAM: ABC-2 type transporter; ABC transporter 2920927 10581012 Trebr_2474 Treponema brennaborense DSM 12168 ABC transporter YP_004441011.1 2920205 R 906968 CDS YP_004441012.1 332299090 10581013 complement(2920924..2921715) 1 NC_015500.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: elm:ELI_4477 hypothetical protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504921401; PFAM: ABC transporter; Phosphonate-transporting ATPase 2921715 10581013 Trebr_2475 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004441012.1 2920924 R 906968 CDS YP_004441013.1 332299091 10581014 complement(2921795..2922526) 1 NC_015500.1 InterPro IPR004223; KEGG: csh:Closa_2453 vitamin B12 dependent methionine synthase activation region; PFAM: Vitamin B12 dependent methionine synthase, activation region; SPTR: 5-methyltetrahydrofolate--homocysteine methyltransferase; IMG reference gene:2504921402; PFAM: Vitamin B12 dependent methionine synthase, activation domain; Vitamin B12 dependent methionine synthase activation subunit 2922526 10581014 Trebr_2476 Treponema brennaborense DSM 12168 Vitamin B12 dependent methionine synthase activation subunit YP_004441013.1 2921795 R 906968 CDS YP_004441014.1 332299092 10581015 2922585..2923457 1 NC_015500.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dau:Daud_1317 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504921403; PFAM: Periplasmic binding protein; ABC transporter substrate-binding protein 2923457 10581015 Trebr_2477 Treponema brennaborense DSM 12168 ABC transporter substrate-binding protein YP_004441014.1 2922585 D 906968 CDS YP_004441015.1 332299093 10581016 2923454..2924545 1 NC_015500.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: dau:Daud_1316 transport system permease protein; PFAM: Bacterial transport system permease protein; SPTR: ABC-type cobalamin/Fe3+-siderophores transport system, permease component; IMG reference gene:2504921404; PFAM: FecCD transport family; ABC transporter permease 2924545 10581016 Trebr_2478 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441015.1 2923454 D 906968 CDS YP_004441016.1 332299094 10581017 2924538..2925368 1 NC_015500.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: dau:Daud_1315 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; IMG reference gene:2504921405; PFAM: ABC transporter; iron-chelate-transporting ATPase 2925368 10581017 Trebr_2479 Treponema brennaborense DSM 12168 iron-chelate-transporting ATPase YP_004441016.1 2924538 D 906968 CDS YP_004441017.1 332299095 10581018 2925623..2926675 1 NC_015500.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ppm:PPSC2_c2828 transcriptional regulator; PFAM: ROK; SPTR: Transcriptional regulator; IMG reference gene:2504921406; PFAM: ROK family; ROK family protein 2926675 10581018 Trebr_2480 Treponema brennaborense DSM 12168 ROK family protein YP_004441017.1 2925623 D 906968 CDS YP_004441018.1 332299096 10581019 2926678..2927886 1 NC_015500.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: uncharacterized protein; IMG reference gene:2504921407; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 2927886 10581019 Trebr_2481 Treponema brennaborense DSM 12168 major facilitator superfamily protein YP_004441018.1 2926678 D 906968 CDS YP_004441019.1 332299097 10581020 complement(2928033..2929496) 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR018060; KEGG: ckn:Calkro_0071 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2504921408; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2929496 10581020 Trebr_2482 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004441019.1 2928033 R 906968 CDS YP_004441020.1 332299098 10581021 complement(2929493..2931439) 1 NC_015500.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: ckn:Calkro_0070 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504921409; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 2931439 10581021 Trebr_2483 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004441020.1 2929493 R 906968 CDS YP_004441021.1 332299099 10581022 complement(2931499..2933139) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_0541 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504921410; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2933139 10581022 Trebr_2484 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004441021.1 2931499 R 906968 CDS YP_004441022.1 332299100 10581023 complement(2933160..2934071) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: chd:Calhy_0056 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504921411; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2934071 10581023 Trebr_2485 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441022.1 2933160 R 906968 CDS YP_004441023.1 332299101 10581024 complement(2934144..2935121) 1 NC_015500.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_0539 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504921412; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2935121 10581024 Trebr_2486 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441023.1 2934144 R 906968 CDS YP_004441024.1 332299102 10581025 2935304..2938840 1 NC_015500.1 KEGG: fbc:FB2170_09196 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921413; hypothetical protein 2938840 10581025 Trebr_2487 Treponema brennaborense DSM 12168 hypothetical protein YP_004441024.1 2935304 D 906968 CDS YP_004441025.1 332299103 10581026 2938818..2940254 1 NC_015500.1 COGs: COG5520 O-Glycosyl hydrolase; InterPro IPR001139; KEGG: glucosylceramidase; PFAM: Glycoside hydrolase, family 30; PRIAM: Glucosylceramidase; SPTR: Glucosylceramidase; IMG reference gene:2504921414; PFAM: O-Glycosyl hydrolase family 30; Glucosylceramidase 2940254 10581026 Trebr_2488 Treponema brennaborense DSM 12168 Glucosylceramidase YP_004441025.1 2938818 D 906968 CDS YP_004441026.1 332299104 10581027 2940453..2942513 1 NC_015500.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR013704:IPR007197:IPR006638; KEGG: nth:Nther_2132 hypothetical protein; PFAM: Radical SAM N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: UPF0313 protein CLCAR_1156/CcarbDRAFT_4186; IMG reference gene:2504921415; PFAM: Domain of unknown function (DUF3362); Radical SAM superfamily; Radical SAM N-terminal; TIGRFAM: uncharacterized radical SAM protein YgiQ; Radical SAM domain protein 2942513 10581027 Trebr_2489 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004441026.1 2940453 D 906968 CDS YP_004441027.1 332299105 10581028 2942510..2944390 1 NC_015500.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: geo:Geob_3685 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504921416; PFAM: Radical SAM superfamily; B12 binding domain; Radical SAM domain protein 2944390 10581028 Trebr_2490 Treponema brennaborense DSM 12168 Radical SAM domain protein YP_004441027.1 2942510 D 906968 CDS YP_004441028.1 332299106 10581029 complement(2944380..2945381) 1 NC_015500.1 COGs: COG4571 Outer membrane protease; KEGG: sta:STHERM_c03080 hypothetical protein; SPTR: Hypothetical membrane protein; IMG reference gene:2504921417; PFAM: Omptin family; hypothetical protein 2945381 10581029 Trebr_2491 Treponema brennaborense DSM 12168 hypothetical protein YP_004441028.1 2944380 R 906968 CDS YP_004441029.1 332299107 10581030 complement(2945391..2947010) 1 NC_015500.1 COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: cpr:CPR_0345 cardiolipin synthetase; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthetase family protein; IMG reference gene:2504921418; PFAM: Phospholipase D Active site motif; phospholipase D/Transphosphatidylase 2947010 10581030 Trebr_2492 Treponema brennaborense DSM 12168 phospholipase D/Transphosphatidylase YP_004441029.1 2945391 R 906968 CDS YP_004441030.1 332299108 10581031 2947245..2948909 1 NC_015500.1 KEGG: tde:TDE2751 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921419; hypothetical protein 2948909 10581031 Trebr_2493 Treponema brennaborense DSM 12168 hypothetical protein YP_004441030.1 2947245 D 906968 CDS YP_004441031.1 332299109 10581032 complement(2948975..2949247) 1 NC_015500.1 KEGG: ssm:Spirs_0324 leader peptide processing enzyme; SPTR: Leader peptide processing enzyme; IMG reference gene:2504921420; leader peptide processing enzyme 2949247 10581032 Trebr_2494 Treponema brennaborense DSM 12168 leader peptide processing enzyme YP_004441031.1 2948975 R 906968 CDS YP_004441032.1 332299110 10581033 complement(2949251..2949823) 1 NC_015500.1 COGs: COG0597 Lipoprotein signal peptidase; HAMAP: Peptidase A8, signal peptidase II; InterPro IPR001872; KEGG: sta:STHERM_c21430 signal peptidase II; PFAM: Peptidase A8, signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: Peptidase A8, signal peptidase II; IMG reference gene:2504921421; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase; lipoprotein signal peptidase 2949823 10581033 Trebr_2495 Treponema brennaborense DSM 12168 lipoprotein signal peptidase YP_004441032.1 2949251 R 906968 CDS YP_004441033.1 332299111 10581034 complement(2949896..2950663) 1 NC_015500.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: tde:TDE2208 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: uncharacterized protein; TIGRFAM: NGG1p interacting factor 3, NIF3; IMG reference gene:2504921422; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; NGG1p interacting factor 3 protein, NIF3 2950663 10581034 Trebr_2496 Treponema brennaborense DSM 12168 NGG1p interacting factor 3 protein, NIF3 YP_004441033.1 2949896 R 906968 CDS YP_004441034.1 332299112 10581035 complement(2950660..2951913) 1 NC_015500.1 IMG reference gene:2504921423; hypothetical protein 2951913 10581035 Trebr_2497 Treponema brennaborense DSM 12168 hypothetical protein YP_004441034.1 2950660 R 906968 CDS YP_004441035.1 332299113 10581036 2952038..2953555 1 NC_015500.1 COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR006675; KEGG: ssm:Spirs_0320 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG; IMG reference gene:2504921424; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; signal transduction protein 2953555 10581036 Trebr_2498 Treponema brennaborense DSM 12168 signal transduction protein YP_004441035.1 2952038 D 906968 CDS YP_004441036.1 332299114 10581037 complement(2953613..2954434) 1 NC_015500.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: tde:TDE0050 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family; IMG reference gene:2504921425; PFAM: SpoU rRNA Methylase family; tRNA/rRNA methyltransferase SpoU 2954434 10581037 Trebr_2499 Treponema brennaborense DSM 12168 tRNA/rRNA methyltransferase SpoU YP_004441036.1 2953613 R 906968 CDS YP_004441037.1 332299115 10581038 complement(2954436..2955584) 1 NC_015500.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: tde:TDE0051 alcohol dehydrogenase, iron-containing; PFAM: Alcohol dehydrogenase, iron-type; SPTR: Alcohol dehydrogenase, iron-containing; IMG reference gene:2504921426; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 2955584 10581038 Trebr_2500 Treponema brennaborense DSM 12168 iron-containing alcohol dehydrogenase YP_004441037.1 2954436 R 906968 CDS YP_004441038.1 332299116 10581039 complement(2955674..2955961) 1 NC_015500.1 InterPro IPR007412; KEGG: tde:TDE0201 hypothetical protein; PFAM: Anti-sigma-28 factor, FlgM; SPTR: Anti-sigma-28 factor, FlgM; TIGRFAM: flagellar biosynthesis anti-sigma factor protein FlgM; IMG reference gene:2504921427; PFAM: Anti-sigma-28 factor, FlgM; flagellar biosynthesis anti-sigma factor protein FlgM 2955961 10581039 Trebr_2501 Treponema brennaborense DSM 12168 flagellar biosynthesis anti-sigma factor protein FlgM YP_004441038.1 2955674 R 906968 CDS YP_004441039.1 332299117 10581040 complement(2955951..2956685) 1 NC_015500.1 COGs: COG0313 methyltransferase; HAMAP: Ribosomal RNA small subunit methyltransferase I; InterPro IPR000878:IPR008189; KEGG: tde:TDE0200 tetrapyrrole methylase family protein; PFAM: Tetrapyrrole methylase; SPTR: Ribosomal RNA small subunit methyltransferase I; TIGRFAM: Uncharacterised protein family UPF0011; IMG reference gene:2504921428; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family; Ribosomal RNA small subunit methyltransferase I 2956685 10581040 Trebr_2502 Treponema brennaborense DSM 12168 Ribosomal RNA small subunit methyltransferase I YP_004441039.1 2955951 R 906968 CDS YP_004441040.1 332299118 10581041 complement(2956837..2957838) 1 NC_015500.1 COGs: COG1073 Hydrolase of the alpha/beta superfamily; KEGG: cpf:CPF_1158 hypothetical protein; SPTR: X-Pro dipeptidyl-peptidase (S15 family); IMG reference gene:2504921429; hypothetical protein 2957838 10581041 Trebr_2503 Treponema brennaborense DSM 12168 hypothetical protein YP_004441040.1 2956837 R 906968 CDS YP_004441041.1 332299119 10581042 complement(2957872..2958597) 1 NC_015500.1 KEGG: tde:TDE1322 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921430; hypothetical protein 2958597 10581042 Trebr_2504 Treponema brennaborense DSM 12168 hypothetical protein YP_004441041.1 2957872 R 906968 CDS YP_004441042.1 332299120 10581043 complement(2958670..2959422) 1 NC_015500.1 KEGG: tde:TDE1322 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921431; hypothetical protein 2959422 10581043 Trebr_2505 Treponema brennaborense DSM 12168 hypothetical protein YP_004441042.1 2958670 R 906968 CDS YP_004441043.1 332299121 10581044 2959942..2960496 1 NC_015500.1 IMG reference gene:2504921432; hypothetical protein 2960496 10581044 Trebr_2506 Treponema brennaborense DSM 12168 hypothetical protein YP_004441043.1 2959942 D 906968 CDS YP_004441044.1 332299122 10581045 2960483..2961238 1 NC_015500.1 InterPro IPR000792; PFAM: Transcription regulator LuxR, C-terminal; IMG reference gene:2504921433; PFAM: Bacterial regulatory proteins, luxR family; regulatory protein LuxR 2961238 10581045 Trebr_2507 Treponema brennaborense DSM 12168 regulatory protein LuxR YP_004441044.1 2960483 D 906968 CDS YP_004441045.1 332299123 10581046 complement(2961245..2962228) 1 NC_015500.1 IMG reference gene:2504921434; hypothetical protein 2962228 10581046 Trebr_2508 Treponema brennaborense DSM 12168 hypothetical protein YP_004441045.1 2961245 R 906968 CDS YP_004441046.1 332299124 10581047 complement(2962567..2964897) 1 NC_015500.1 COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterPro IPR001264:IPR001460:IPR009647; KEGG: ssm:Spirs_1458 peptidoglycan glycosyltransferase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; Penicillin-binding, C-terminal; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1C; IMG reference gene:2504921435; PFAM: Penicillin-Binding Protein C-terminus Family; Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1C; peptidoglycan glycosyltransferase 2964897 10581047 Trebr_2509 Treponema brennaborense DSM 12168 peptidoglycan glycosyltransferase YP_004441046.1 2962567 R 906968 CDS YP_004441047.1 332299125 10581048 complement(2964878..2970904) 1 NC_015500.1 COGs: COG2373 Large extracellular alpha-helical protein; InterPro IPR002890:IPR011625:IPR001599; KEGG: ssm:Spirs_1457 alpha-2-macroglobulin domain protein 2; PFAM: Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin; SPTR: Alpha-2-macroglobulin family N-region; IMG reference gene:2504921436; PFAM: Alpha-2-macroglobulin family; MG2 domain; Alpha-2-macroglobulin MG1 domain; Alpha-2-macroglobulin family N-terminal region; alpha-2-macroglobulin domain-containing protein 2 2970904 10581048 Trebr_2510 Treponema brennaborense DSM 12168 alpha-2-macroglobulin domain-containing protein 2 YP_004441047.1 2964878 R 906968 CDS YP_004441048.1 332299126 10581049 complement(2970986..2971918) 1 NC_015500.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Undecaprenyl-diphosphatase; InterPro IPR003824; KEGG: tde:TDE0172 undecaprenyl pyrophosphate phosphatase; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase; IMG reference gene:2504921437; PFAM: Bacitracin resistance protein BacA; UDP-diphosphatase 2971918 10581049 Trebr_2511 Treponema brennaborense DSM 12168 UDP-diphosphatase YP_004441048.1 2970986 R 906968 CDS YP_004441049.1 332299127 10581050 2972121..2972297 1 NC_015500.1 KEGG: chy:CHY_1707 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921438; hypothetical protein 2972297 10581050 Trebr_2512 Treponema brennaborense DSM 12168 hypothetical protein YP_004441049.1 2972121 D 906968 CDS YP_004441050.1 332299128 10581051 2972368..2973279 1 NC_015500.1 KEGG: sta:STHERM_c11560 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921439; hypothetical protein 2973279 10581051 Trebr_2513 Treponema brennaborense DSM 12168 hypothetical protein YP_004441050.1 2972368 D 906968 CDS YP_004441051.1 332299129 10581052 complement(2973337..2974929) 1 NC_015500.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; HAMAP: Hybrid cluster protein; InterPro IPR004137:IPR010048; KEGG: csh:Closa_2549 hybrid cluster protein; PFAM: Prismane; SPTR: Hydroxylamine reductase; TIGRFAM: Hybrid cluster protein; IMG reference gene:2504921440; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: hydroxylamine reductase; hydroxylamine reductase 2974929 10581052 Trebr_2514 Treponema brennaborense DSM 12168 hydroxylamine reductase YP_004441051.1 2973337 R 906968 CDS YP_004441052.1 332299130 10581053 complement(2974994..2975737) 1 NC_015500.1 InterPro IPR001450; KEGG: 4Fe-4S ferredoxin, iron-sulfur binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding protein; IMG reference gene:2504921441; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 2975737 10581053 Trebr_2515 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004441052.1 2974994 R 906968 CDS YP_004441053.1 332299131 10581054 2975830..2976510 1 NC_015500.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: afn:Acfer_1732 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; SPTR: uncharacterized protein; IMG reference gene:2504921442; PFAM: Cyclic nucleotide-binding domain; CarD family transcriptional regulator 2976510 10581054 Trebr_2516 Treponema brennaborense DSM 12168 CarD family transcriptional regulator YP_004441053.1 2975830 D 906968 CDS YP_004441054.1 332299132 10581055 2976649..2977308 1 NC_015500.1 COGs: COG0461 Orotate phosphoribosyltransferase; HAMAP: Orotate phosphoribosyltransferase; InterPro IPR000836:IPR004467; KEGG: orotate phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyl transferase; IMG reference gene:2504921443; PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 2977308 10581055 Trebr_2517 Treponema brennaborense DSM 12168 orotate phosphoribosyltransferase YP_004441054.1 2976649 D 906968 CDS YP_004441055.1 332299133 10581056 complement(2977370..2978356) 1 NC_015500.1 COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: tpp:TPASS_0291 hypothetical protein; PFAM: FMN-dependent dehydrogenase; SPTR: FMN-dependent dehydrogenase family protein; IMG reference gene:2504921444; PFAM: FMN-dependent dehydrogenase; FMN-dependent alpha-hydroxy acid dehydrogenase 2978356 10581056 Trebr_2518 Treponema brennaborense DSM 12168 FMN-dependent alpha-hydroxy acid dehydrogenase YP_004441055.1 2977370 R 906968 CDS YP_004441056.1 332299134 10581057 complement(2978341..2979426) 1 NC_015500.1 COGs: COG0205 6-phosphofructokinase; HAMAP: 6-phosphofructokinase; InterPro IPR000023; KEGG: sta:STHERM_c00290 6-phosphofructokinase 3; PFAM: Phosphofructokinase; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase; IMG reference gene:2504921445; PFAM: Phosphofructokinase; TIGRFAM: phosphofructokinase; 6-phosphofructokinase 2979426 10581057 Trebr_2519 Treponema brennaborense DSM 12168 6-phosphofructokinase YP_004441056.1 2978341 R 906968 CDS YP_004441057.1 332299135 10581058 complement(2979573..2980745) 1 NC_015500.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR013196:IPR004143:IPR003142:IPR004408; KEGG: tde:TDE0041 BirA bifunctional protein; PFAM: Biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11; Biotin protein ligase, C-terminal; SPTR: BirA bifunctional protein; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; IMG reference gene:2504921446; PFAM: HTH domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: BirA biotin operon repressor domain; birA, biotin-[acetyl-CoA-carboxylase] ligase region; biotin-(acetyl-CoA carboxylase) ligase 2980745 10581058 Trebr_2520 Treponema brennaborense DSM 12168 biotin-(acetyl-CoA carboxylase) ligase YP_004441057.1 2979573 R 906968 CDS YP_004441058.1 332299136 10581059 complement(2980742..2981404) 1 NC_015500.1 KEGG: cpy:Cphy_2614 nitrogen regulatory protein P-II; SPTR: Regulatory protein, P-II family; IMG reference gene:2504921447; hypothetical protein 2981404 10581059 Trebr_2521 Treponema brennaborense DSM 12168 hypothetical protein YP_004441058.1 2980742 R 906968 CDS YP_004441059.1 332299137 10581060 complement(2981401..2982885) 1 NC_015500.1 InterPro IPR011435; KEGG: aoe:Clos_0656 hypothetical protein; PFAM: Protein of unknown function DUF1538; SPTR: membrane protein; IMG reference gene:2504921448; PFAM: Protein of unknown function (DUF1538); hypothetical protein 2982885 10581060 Trebr_2522 Treponema brennaborense DSM 12168 hypothetical protein YP_004441059.1 2981401 R 906968 CDS YP_004441060.1 332299138 10581061 complement(2982896..2983591) 1 NC_015500.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR010049; KEGG: csh:Closa_0055 MTA/SAH nucleosidase; PFAM: Nucleoside phosphorylase; PRIAM: Adenosylhomocysteine nucleosidase; SPTR: MTA/SAH nucleosidase; TIGRFAM: MTA/SAH nucleosidase; IMG reference gene:2504921449; PFAM: Phosphorylase superfamily; TIGRFAM: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; MTA/SAH nucleosidase 2983591 10581061 Trebr_2523 Treponema brennaborense DSM 12168 MTA/SAH nucleosidase YP_004441060.1 2982896 R 906968 CDS YP_004441061.1 332299139 10581062 complement(2983816..2985012) 1 NC_015500.1 COGs: COG2267 Lysophospholipase; KEGG: ccb:Clocel_2090 alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold; IMG reference gene:2504921450; PFAM: lysophospholipase; hypothetical protein 2985012 10581062 Trebr_2524 Treponema brennaborense DSM 12168 hypothetical protein YP_004441061.1 2983816 R 906968 CDS YP_004441062.1 332299140 10581063 2985424..2986107 1 NC_015500.1 COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: tde:TDE2163 hypothetical protein; PFAM: Peptidase, membrane zinc metallopeptidase, SPTR: uncharacterized protein; IMG reference gene:2504921451; PFAM: neutral zinc metallopeptidase; peptidase membrane zinc metallopeptidase 2986107 10581063 Trebr_2525 Treponema brennaborense DSM 12168 peptidase membrane zinc metallopeptidase YP_004441062.1 2985424 D 906968 CDS YP_004441063.1 332299141 10581064 2986301..2987608 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ssm:Spirs_1368 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1; IMG reference gene:2504921452; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2987608 10581064 Trebr_2526 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004441063.1 2986301 D 906968 CDS YP_004441064.1 332299142 10581065 2987721..2988632 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_1367 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504921453; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2988632 10581065 Trebr_2527 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441064.1 2987721 D 906968 CDS YP_004441065.1 332299143 10581066 2988701..2989567 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_3220 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504921454; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 2989567 10581066 Trebr_2528 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441065.1 2988701 D 906968 CDS YP_004441066.1 332299144 10581067 2989680..2990306 1 NC_015500.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: tle:Tlet_2032 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504921455; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; HAD-superfamily hydrolase 2990306 10581067 Trebr_2529 Treponema brennaborense DSM 12168 HAD-superfamily hydrolase YP_004441066.1 2989680 D 906968 CDS YP_004441067.1 332299145 10581068 2990327..2991373 1 NC_015500.1 COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: sth:STH1157 iron ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Iron ABC transporter substrate-binding protein; IMG reference gene:2504921456; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 2991373 10581068 Trebr_2530 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004441067.1 2990327 D 906968 CDS YP_004441068.1 332299146 10581069 complement(2991427..2992239) 1 NC_015500.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR018060; KEGG: csh:Closa_2526 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2504921457; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2992239 10581069 Trebr_2531 Treponema brennaborense DSM 12168 AraC family transcriptional regulator YP_004441068.1 2991427 R 906968 CDS YP_004441069.1 332299147 10581070 complement(2992236..2994146) 1 NC_015500.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: ssm:Spirs_1363 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Two-component sensor histidine kinase; IMG reference gene:2504921458; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 2994146 10581070 Trebr_2532 Treponema brennaborense DSM 12168 integral membrane sensor signal transduction histidine kinase YP_004441069.1 2992236 R 906968 CDS YP_004441070.1 332299148 10581071 2994286..2994711 1 NC_015500.1 InterPro IPR000835; KEGG: ols:Olsu_1650 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: uncharacterized protein; IMG reference gene:2504921459; PFAM: MarR family; regulatory protein MarR 2994711 10581071 Trebr_2533 Treponema brennaborense DSM 12168 regulatory protein MarR YP_004441070.1 2994286 D 906968 CDS YP_004441071.1 332299149 10581072 2994809..2996140 1 NC_015500.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: eel:EUBELI_01492 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; IMG reference gene:2504921460; PFAM: MatE; TIGRFAM: efflux protein, MATE family; multi antimicrobial extrusion protein MatE 2996140 10581072 Trebr_2534 Treponema brennaborense DSM 12168 multi antimicrobial extrusion protein MatE YP_004441071.1 2994809 D 906968 CDS YP_004441072.1 332299150 10581073 2996396..2996758 1 NC_015500.1 KEGG: elm:ELI_2299 hypothetical cytosolic protein; SPTR: uncharacterized protein; IMG reference gene:2504921461; hypothetical protein 2996758 10581073 Trebr_2535 Treponema brennaborense DSM 12168 hypothetical protein YP_004441072.1 2996396 D 906968 CDS YP_004441073.1 332299151 10581074 complement(2996891..2997724) 1 NC_015500.1 COGs: COG0657 Esterase/lipase; KEGG: cpy:Cphy_3014 acetyl esterase; SPTR: uncharacterized protein; IMG reference gene:2504921462; PFAM: alpha/beta hydrolase fold; acetyl esterase 2997724 10581074 Trebr_2536 Treponema brennaborense DSM 12168 acetyl esterase YP_004441073.1 2996891 R 906968 CDS YP_004441074.1 332299152 10581075 2997913..2999130 1 NC_015500.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: eel:EUBELI_20098 two-component system response regulator; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: two-component system response regulator; IMG reference gene:2504921463; PFAM: HD domain; metal dependent phosphohydrolase 2999130 10581075 Trebr_2537 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004441074.1 2997913 D 906968 CDS YP_004441075.1 332299153 10581076 2999313..3001229 1 NC_015500.1 COGs: COG1164 Oligoendopeptidase F; InterPro IPR013647:IPR001567; KEGG: tde:TDE2001 oligoendopeptidase F, PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; Peptidase M3B, oligopeptidase F, N-terminal; SPTR: Oligoendopeptidase F, ; IMG reference gene:2504921464; PFAM: Oligopeptidase F; Peptidase family M3; TIGRFAM: oligoendopeptidase, pepF/M3 family; peptidase M3A and M3B thimet/oligopeptidase F 3001229 10581076 Trebr_2538 Treponema brennaborense DSM 12168 peptidase M3A and M3B thimet/oligopeptidase F YP_004441075.1 2999313 D 906968 CDS YP_004441076.1 332299154 10581077 3001242..3002156 1 NC_015500.1 COGs: COG0348 Polyferredoxin; InterPro IPR001450; KEGG: mae:Maeo_0832 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2504921465; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 3002156 10581077 Trebr_2539 Treponema brennaborense DSM 12168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_004441076.1 3001242 D 906968 CDS YP_004441077.1 332299155 10581078 3002153..3003040 1 NC_015500.1 COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: UBA/ThiF-type NAD/FAD-binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: ThiF family protein; IMG reference gene:2504921466; PFAM: ThiF family; UBA/THIF-type NAD/FAD binding protein 3003040 10581078 Trebr_2540 Treponema brennaborense DSM 12168 UBA/THIF-type NAD/FAD binding protein YP_004441077.1 3002153 D 906968 CDS YP_004441078.1 332299156 10581079 3003383..3004258 1 NC_015500.1 KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: uncharacterized protein; IMG reference gene:2504921467; TIGRFAM: conserved hypothetical protein ( transposase or invertase); tetracycline resistance leader peptide 3004258 10581079 Trebr_2541 Treponema brennaborense DSM 12168 tetracycline resistance leader peptide YP_004441078.1 3003383 D 906968 CDS YP_004441079.1 332299157 10581080 complement(3004334..3004528) 1 NC_015500.1 IMG reference gene:2504921468; hypothetical protein 3004528 10581080 Trebr_2542 Treponema brennaborense DSM 12168 hypothetical protein YP_004441079.1 3004334 R 906968 CDS YP_004441080.1 332299158 10581081 3004656..3004985 1 NC_015500.1 InterPro IPR001387; KEGG: ssm:Spirs_2779 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504921469; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 3004985 10581081 Trebr_2543 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004441080.1 3004656 D 906968 CDS YP_004441081.1 332299159 10581083 complement(3005294..3006250) 1 NC_015500.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ROK family protein; PFAM: ROK; PRIAM: Glucokinase; SPTR: ROK family protein; manually curated; IMG reference gene:2504921471; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase); glucokinase 3006250 10581083 Trebr_2545 Treponema brennaborense DSM 12168 glucokinase YP_004441081.1 3005294 R 906968 CDS YP_004441082.1 332299160 10581084 3006353..3007135 1 NC_015500.1 COGs: COG3142 Uncharacterized protein involved in copper resistance; HAMAP: Copper homeostasis protein cutC; InterPro IPR005627; KEGG: csh:Closa_2248 CutC family protein; PFAM: CutC; SPTR: Uncharacterized protein involved in copper resistance; IMG reference gene:2504921472; PFAM: CutC family; Copper homeostasis protein cutC 3007135 10581084 Trebr_2546 Treponema brennaborense DSM 12168 Copper homeostasis protein cutC YP_004441082.1 3006353 D 906968 CDS YP_004441083.1 332299161 10581085 complement(3007184..3008050) 1 NC_015500.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: cst:CLOST_1867 hypothetical protein; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: uncharacterized protein; IMG reference gene:2504921473; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; LysR family transcriptional regulator 3008050 10581085 Trebr_2547 Treponema brennaborense DSM 12168 LysR family transcriptional regulator YP_004441083.1 3007184 R 906968 CDS YP_004441084.1 332299162 10581087 complement(3009395..3010417) 1 NC_015500.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bpb:bpr_I0932 2-dehydro-3-deoxygluconokinase KdgK; PFAM: Carbohydrate/purine kinase; SPTR: KHG/KDPG family aldolase/carbohydrate kinase, PfkB family; IMG reference gene:2504921475; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 3010417 10581087 Trebr_2549 Treponema brennaborense DSM 12168 PfkB domain-containing protein YP_004441084.1 3009395 R 906968 CDS YP_004441085.1 332299163 10581088 complement(3010707..3012056) 1 NC_015500.1 COGs: COG5434 Endopygalactorunase; InterPro IPR000743:IPR006626; KEGG: sta:STHERM_c04310 hypothetical protein; PFAM: Glycoside hydrolase, family 28; PRIAM: Polygalacturonase; SPTR: uncharacterized protein; IMG reference gene:2504921476; PFAM: Glycosyl hydrolases family 28; Polygalacturonase 3012056 10581088 Trebr_2550 Treponema brennaborense DSM 12168 Polygalacturonase YP_004441085.1 3010707 R 906968 CDS YP_004441086.1 332299164 10581089 complement(3012150..3013235) 1 NC_015500.1 COGs: COG4677 Pectin methylesterase; KEGG: cja:CJA_0041 pectin methylesterase, , pme8A; SPTR: Pectin methylesterase, , pme8A; IMG reference gene:2504921477; PFAM: Pectinesterase; hypothetical protein 3013235 10581089 Trebr_2551 Treponema brennaborense DSM 12168 hypothetical protein YP_004441086.1 3012150 R 906968 CDS YP_004441087.1 332299165 10581090 3013367..3014260 1 NC_015500.1 KEGG: sua:Saut_1390 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921478; PFAM: GIY-YIG catalytic domain; hypothetical protein 3014260 10581090 Trebr_2552 Treponema brennaborense DSM 12168 hypothetical protein YP_004441087.1 3013367 D 906968 CDS YP_004441088.1 332299166 10581091 3014289..3014795 1 NC_015500.1 KEGG: cpy:Cphy_0999 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921479; hypothetical protein 3014795 10581091 Trebr_2553 Treponema brennaborense DSM 12168 hypothetical protein YP_004441088.1 3014289 D 906968 CDS YP_004441089.1 332299167 10581092 3014951..3015679 1 NC_015500.1 KEGG: outer membrane protein; SPTR: Outer membrane protein; IMG reference gene:2504921480; PFAM: Surface lipoprotein of Spirochaetales order; outer membrane protein 3015679 10581092 Trebr_2554 Treponema brennaborense DSM 12168 outer membrane protein YP_004441089.1 3014951 D 906968 CDS YP_004441090.1 332299168 10581093 complement(3015804..3017150) 1 NC_015500.1 COGs: COG3866 Pectate lyase; InterPro IPR002022; KEGG: cco:CCC13826_0280 AAA ATPase family protein; PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; SPTR: Pectate lyase; IMG reference gene:2504921481; PFAM: Pectate lyase; Pectate lyase/Amb allergen 3017150 10581093 Trebr_2555 Treponema brennaborense DSM 12168 Pectate lyase/Amb allergen YP_004441090.1 3015804 R 906968 CDS YP_004441091.1 332299169 10581094 complement(3017369..3019888) 1 NC_015500.1 InterPro IPR000070; KEGG: cja:CJA_0041 pectin methylesterase, , pme8A; PFAM: Pectinesterase, catalytic; SPTR: Pectin methylesterase, , pme8A; IMG reference gene:2504921482; PFAM: Pectinesterase; pectinesterase 3019888 10581094 Trebr_2556 Treponema brennaborense DSM 12168 pectinesterase YP_004441091.1 3017369 R 906968 CDS YP_004441092.1 332299170 10581095 complement(3019985..3020539) 1 NC_015500.1 KEGG: eel:EUBELI_01249 polysaccharide lyase family 1 modular protein with two candidate pectate lyase domains; SPTR: Polysaccharide Lyase Family 1 modular protein with two candidate pectate lyase domains; IMG reference gene:2504921483; hypothetical protein 3020539 10581095 Trebr_2557 Treponema brennaborense DSM 12168 hypothetical protein YP_004441092.1 3019985 R 906968 CDS YP_004441093.1 332299171 10581096 complement(3020591..3021085) 1 NC_015500.1 IMG reference gene:2504921484; hypothetical protein 3021085 10581096 Trebr_2558 Treponema brennaborense DSM 12168 hypothetical protein YP_004441093.1 3020591 R 906968 CDS YP_004441094.1 332299172 10581097 complement(3021387..3022322) 1 NC_015500.1 COGs: COG3965 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: cyt:cce_2685 cation efflux protein; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; IMG reference gene:2504921485; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 3022322 10581097 Trebr_2559 Treponema brennaborense DSM 12168 cation diffusion facilitator family transporter YP_004441094.1 3021387 R 906968 CDS YP_004441095.1 332299173 10581098 complement(3022445..3024166) 1 NC_015500.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR005147:IPR004531; KEGG: tde:TDE1927 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase, B5; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; IMG reference gene:2504921486; PFAM: tRNA synthetase B5 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; phenylalanyl-tRNA synthetase subunit beta 3024166 10581098 Trebr_2560 Treponema brennaborense DSM 12168 phenylalanyl-tRNA synthetase subunit beta YP_004441095.1 3022445 R 906968 CDS YP_004441096.1 332299174 10581099 complement(3024418..3024558) 1 NC_015500.1 IMG reference gene:2504921487; hypothetical protein 3024558 10581099 Trebr_2561 Treponema brennaborense DSM 12168 hypothetical protein YP_004441096.1 3024418 R 906968 CDS YP_004441097.1 332299175 10581100 complement(3024713..3025381) 1 NC_015500.1 IMG reference gene:2504921488; hypothetical protein 3025381 10581100 Trebr_2562 Treponema brennaborense DSM 12168 hypothetical protein YP_004441097.1 3024713 R 906968 CDS YP_004441098.1 332299176 10581101 complement(3025612..3026253) 1 NC_015500.1 KEGG: ter:Tery_2223 hypothetical protein; SPTR: Leucine-rich repeat, typical subtype; IMG reference gene:2504921489; hypothetical protein 3026253 10581101 Trebr_2563 Treponema brennaborense DSM 12168 hypothetical protein YP_004441098.1 3025612 R 906968 CDS YP_004441099.1 332299177 10581102 complement(3026274..3026459) 1 NC_015500.1 IMG reference gene:2504921490; hypothetical protein 3026459 10581102 Trebr_2564 Treponema brennaborense DSM 12168 hypothetical protein YP_004441099.1 3026274 R 906968 CDS YP_004441100.1 332299178 10581103 3026980..3027240 1 NC_015500.1 KEGG: cdf:CD1724 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921491; hypothetical protein 3027240 10581103 Trebr_2565 Treponema brennaborense DSM 12168 hypothetical protein YP_004441100.1 3026980 D 906968 CDS YP_004441101.1 332299179 10581104 3027264..3027899 1 NC_015500.1 COGs: COG4832 conserved hypothetical protein; InterPro IPR019233; KEGG: lin:lin2189 hypothetical protein; PFAM: Protein of unknown function DUF2174, N-terminal; SPTR: uncharacterized protein; IMG reference gene:2504921492; PFAM: Uncharacterized conserved protein (DUF2174); hypothetical protein 3027899 10581104 Trebr_2566 Treponema brennaborense DSM 12168 hypothetical protein YP_004441101.1 3027264 D 906968 CDS YP_004441102.1 332299180 10581105 3027929..3028561 1 NC_015500.1 COGs: COG4832 conserved hypothetical protein; InterPro IPR019233; KEGG: fsu:Fisuc_0606 hypothetical protein; PFAM: Protein of unknown function DUF2174, N-terminal; SPTR: uncharacterized protein; IMG reference gene:2504921493; PFAM: Uncharacterized conserved protein (DUF2174); hypothetical protein 3028561 10581105 Trebr_2567 Treponema brennaborense DSM 12168 hypothetical protein YP_004441102.1 3027929 D 906968 CDS YP_004441103.1 332299181 10581106 3028789..3031425 1 NC_015500.1 KEGG: tde:TDE1941 hypothetical protein; SPTR: FG-GAP repeat domain protein; IMG reference gene:2504921494; hypothetical protein 3031425 10581106 Trebr_2568 Treponema brennaborense DSM 12168 hypothetical protein YP_004441103.1 3028789 D 906968 CDS YP_004441104.1 332299182 10581107 3031422..3032522 1 NC_015500.1 KEGG: tde:TDE1940 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921495; hypothetical protein 3032522 10581107 Trebr_2569 Treponema brennaborense DSM 12168 hypothetical protein YP_004441104.1 3031422 D 906968 CDS YP_004441105.1 332299183 10581108 3032772..3033491 1 NC_015500.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c02090 ATP-binding/permease MacB; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein; IMG reference gene:2504921496; PFAM: ABC transporter; Phosphonate-transporting ATPase 3033491 10581108 Trebr_2570 Treponema brennaborense DSM 12168 Phosphonate-transporting ATPase YP_004441105.1 3032772 D 906968 CDS YP_004441106.1 332299184 10581109 3033506..3034783 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02080 permease, involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: permease, involved in lipoprotein release; IMG reference gene:2504921497; PFAM: Predicted permease; hypothetical protein 3034783 10581109 Trebr_2571 Treponema brennaborense DSM 12168 hypothetical protein YP_004441106.1 3033506 D 906968 CDS YP_004441107.1 332299185 10581110 3034802..3036148 1 NC_015500.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02070 permease involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: permease involved in lipoprotein release; IMG reference gene:2504921498; PFAM: Predicted permease; hypothetical protein 3036148 10581110 Trebr_2572 Treponema brennaborense DSM 12168 hypothetical protein YP_004441107.1 3034802 D 906968 CDS YP_004441108.1 332299186 10581111 3036183..3036923 1 NC_015500.1 KEGG: sta:STHERM_c02060 outer membrane protein involved in lipoprotein sorting; SPTR: uncharacterized protein; IMG reference gene:2504921499; outer membrane protein involved in lipoprotein sorting 3036923 10581111 Trebr_2573 Treponema brennaborense DSM 12168 outer membrane protein involved in lipoprotein sorting YP_004441108.1 3036183 D 906968 CDS YP_004441109.1 332299187 10581112 3036917..3038143 1 NC_015500.1 KEGG: sta:STHERM_c02050 hypothetical protein; SPTR: uncharacterized protein; IMG reference gene:2504921500; hypothetical protein 3038143 10581112 Trebr_2574 Treponema brennaborense DSM 12168 hypothetical protein YP_004441109.1 3036917 D 906968 CDS YP_004441110.1 332299188 10581113 3038557..3039054 1 NC_015500.1 InterPro IPR001387; KEGG: apv:Apar_1239 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: DNA-binding helix-turn-helix protein; IMG reference gene:2504921501; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein 3039054 10581113 Trebr_2575 Treponema brennaborense DSM 12168 helix-turn-helix domain-containing protein YP_004441110.1 3038557 D 906968 CDS YP_004441111.1 332299189 10581114 3039241..3039537 1 NC_015500.1 IMG reference gene:2504921502; hypothetical protein 3039537 10581114 Trebr_2576 Treponema brennaborense DSM 12168 hypothetical protein YP_004441111.1 3039241 D 906968 CDS YP_004441112.1 332299190 10581115 3039627..3040907 1 NC_015500.1 InterPro IPR011701; KEGG: dsy:DSY1410 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: uncharacterized protein; IMG reference gene:2504921503; PFAM: Bacterial protein of unknown function (DUF894); major facilitator superfamily protein 3040907 10581115 Trebr_2577 Treponema brennaborense DSM 12168 major facilitator superfamily protein YP_004441112.1 3039627 D 906968 CDS YP_004441113.1 332299191 10581116 3040920..3041915 1 NC_015500.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: dtu:Dtur_0547 transcriptional regulator, LacI family; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: uncharacterized protein; IMG reference gene:2504921504; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 3041915 10581116 Trebr_2578 Treponema brennaborense DSM 12168 LacI family transcriptional regulator YP_004441113.1 3040920 D 906968 CDS YP_004441114.1 332299192 10581117 complement(3041934..3043886) 1 NC_015500.1 KEGG: cth:Cthe_0009 YD repeat-containing protein; SPTR: YD repeat containing protein; IMG reference gene:2504921505; hypothetical protein 3043886 10581117 Trebr_2579 Treponema brennaborense DSM 12168 hypothetical protein YP_004441114.1 3041934 R 906968 CDS YP_004441115.1 332299193 10581118 3043995..3044855 1 NC_015500.1 COGs: COG3294 conserved hypothetical protein; KEGG: ssm:Spirs_0575 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504921506; metal dependent phosphohydrolase 3044855 10581118 Trebr_2580 Treponema brennaborense DSM 12168 metal dependent phosphohydrolase YP_004441115.1 3043995 D 906968 CDS YP_004441116.1 332299194 10581119 3044864..3045682 1 NC_015500.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: hypothetical protein; PFAM: Protein of unknown function DUF208; SPTR: uncharacterized protein; IMG reference gene:2504921507; PFAM: Uncharacterized BCR, COG1636; hypothetical protein 3045682 10581119 Trebr_2581 Treponema brennaborense DSM 12168 hypothetical protein YP_004441116.1 3044864 D 906968 CDS YP_004441117.1 332299195 10581120 complement(3045788..3046660) 1 NC_015500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csh:Closa_3982 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Sugar permease; IMG reference gene:2504921508; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 3046660 10581120 Trebr_2582 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441117.1 3045788 R 906968 CDS YP_004441118.1 332299196 10581121 complement(3046677..3047588) 1 NC_015500.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: csh:Closa_3983 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type sugar transport system, permease component; IMG reference gene:2504921509; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter permease 3047588 10581121 Trebr_2583 Treponema brennaborense DSM 12168 ABC transporter permease YP_004441118.1 3046677 R 906968 CDS YP_004441119.1 332299197 10581122 complement(3047657..3048961) 1 NC_015500.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csh:Closa_3984 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: sugar-binding periplasmic protein; IMG reference gene:2504921510; PFAM: Bacterial extracellular solute-binding protein; extracellular solute-binding protein 3048961 10581122 Trebr_2584 Treponema brennaborense DSM 12168 extracellular solute-binding protein YP_004441119.1 3047657 R 906968 CDS YP_004441120.1 332299198 10581123 3049050..3050402 1 NC_015500.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR001048:IPR000182:IPR010167; KEGG: sta:STHERM_c17320 amino acid acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Aspartate/glutamate/uridylate kinase; SPTR: amino acid acetyltransferase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA); IMG reference gene:2504921511; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; amino-acid N-acetyltransferase 3050402 10581123 Trebr_2585 Treponema brennaborense DSM 12168 amino-acid N-acetyltransferase YP_004441120.1 3049050 D 906968 CDS YP_004441121.1 332299199 10581124 complement(3051066..3053519) 1 NC_015500.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR006691:IPR005743; KEGG: tde:TDE0295 DNA gyrase, A subunit; PFAM: DNA topoisomerase, type IIA, subunit A or C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A or C-terminal; SPTR: DNA gyrase, A subunit; TIGRFAM: DNA gyrase, subunit A; IMG reference gene:2504921512; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit; DNA gyrase subunit A 3053519 10581124 Trebr_2586 Treponema brennaborense DSM 12168 DNA gyrase subunit A YP_004441121.1 3051066 R 906968 CDS YP_004441122.1 332299200 10581125 complement(3053601..3055517) 1 NC_015500.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR003594:IPR013506:IPR006171:IPR002288:IPR 001241:IPR011557; KEGG: tde:TDE0002 DNA gyrase, B subunit; PFAM: DNA topoisomerase, type IIA, subunit B, region 2; ATP-binding region, ATPase-like; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit B or N-terminal; ATP-binding region, ATPase-like; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, subunit B; IMG reference gene:2504921513; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit; DNA gyrase subunit B 3055517 10581125 Trebr_2587 Treponema brennaborense DSM 12168 DNA gyrase subunit B YP_004441122.1 3053601 R 906968 CDS