-- dump date 20111121_015458 -- class Genbank::CDS -- table cds_note -- id note NP_788956.1 Similar to Streptomyces coelicolor chromosomal replication initiator protein DnaA or SCO3879 or SCH18.16c SWALL:DNAA_STRCO (SWALL:P27902) (656 aa) fasta scores: E(): 3.8e-67, 53.02% id in 347 aa, and to Micrococcus luteus chromosomal replication initiator protein DnaA SWALL:DNAA_MICLU (SWALL:P21173) (515 aa) fasta scores: E(): 1.1e-64, 42.17% id in 505 aa NP_788957.1 binds the polymerase to DNA and acts as a sliding clamp NP_788958.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_788959.1 Similar to Streptomyces coelicolor hypothetical protein SCO3875 or SCH18.12c SWALL:Y2H5_STRCO (SWALL:P35925) (190 aa) fasta scores: E(): 5.9, 24.32% id in 111 aa NP_788960.1 negatively supercoils closed circular double-stranded DNA NP_788961.1 negatively supercoils closed circular double-stranded DNA NP_788962.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO3872 or SCH18.09c SWALL:Q9KXX6 (EMBL:AL357152) (185 aa) fasta scores: E(): 0.0026, 30.5% id in 118 aa NP_788963.1 Similar to Thermoanaerobacter tengcongensis thiamine pyrophosphokinase Thi80 or Tte1497 SWALL:Q8R9T9 (EMBL:AE013107) (211 aa) fasta scores: E(): 2.5e-09, 29.68% id in 192 aa, and to Bacillus subtilis YloS protein SWALL:O34664 (EMBL:Z99112) (214 aa) fasta scores: E(): 5.7e-08, 30% id in 210 aa NP_788964.1 Similar to Streptomyces coelicolor putative membrane protein SCO3855 or SCH69.25c SWALL:Q9XA09 (EMBL:AL079308) (297 aa) fasta scores: E(): 9.4e-13, 40% id in 155 aa NP_788965.1 integral membrane protein involved in inhibition of the Z-ring formation NP_788966.1 Similar to Streptomyces coelicolor putative glutamine amidotransferase SCO3851 or SCH69.21c SWALL:Q9XA13 (EMBL:AL079308) (212 aa) fasta scores: E(): 1.8e-29, 43.68% id in 206 aa, and to Escherichia coli para-aminobenzoate synthase glutamine amidotransferase component II PabA or b3360 SWALL:PABA_ECOLI (SWALL:P00903) (187 aa) fasta scores: E(): 5e-24, 41.48% id in 188 aa NP_788967.1 Similar to Rhizobium meliloti hypothetical transmembrane protein SMC00853 or R00853 SWALL:Q92RL3 (EMBL:AL591785) (182 aa) fasta scores: E(): 6.7e-26, 49.18% id in 183 aa NP_788968.1 Similar to Streptococcus gordonii Challis probable protease HtpX homolog SWALL:HTPX_STRGC (SWALL:O30795) (297 aa) fasta scores: E(): 1.5e-41, 42.52% id in 301 aa, and to Escherichia coli probable protease HtpX or b1829 SWALL:HTPX_ECOLI (SWALL:P23894) (293 aa) fasta scores: E(): 4.9e-17, 32.05% id in 287 aa NP_788969.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO1562 or SCL11.18 SWALL:Q9L1C0 (EMBL:AL157953) (138 aa) fasta scores: E(): 1.2e-12, 41.02% id in 117 aa NP_788971.1 Similar to Yersinia pestis 2,5-diketo-D-gluconic acid reductase A DkgA or YPO0676 or y3501 SWALL:DKGA_YERPE (SWALL:Q8ZI40) (277 aa) fasta scores: E(): 5.3e-50, 46.71% id in 274 aa, and to Corynebacterium sp. 2,5-diketo-D-gluconic acid reductase A DkgA SWALL:DKGA_CORSP (SWALL:P06632) (277 aa) fasta scores: E(): 1.1e-55, 51.5% id in 266 aa NP_788972.1 Similar to Streptomyces coelicolor putative phosphomannomutase SCO4916 or SCK13.08c SWALL:Q9AD82 (EMBL:AL512667) (549 aa) fasta scores: E(): 9.1e-77, 44.21% id in 536 aa, and to Streptococcus thermophilus phosphoglucomutase PgmA SWALL:Q9K560 (EMBL:AJ243290) (572 aa) fasta scores: E(): 1.1e-28, 33.27% id in 544 aa NP_788973.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_788974.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity NP_788975.1 Similar to Streptomyces coelicolor putative acyl-CoA carboxylase complex A subunit AccA1 SWALL:Q9RGQ6 (EMBL:AF113603) (590 aa) fasta scores: E(): 2.3e-110, 51.67% id in 596 aa, and to Mus musculus pyruvate carboxylase, mitochondrial precursor SWALL:PYC_MOUSE (SWALL:Q05920) (1178 aa) fasta scores: E(): 1.6e-71, 42.26% id in 504 aa NP_788979.1 Doubtful CDS. No significant database matches NP_788980.1 Similar to Saccharopolyspora erythraea propionyl-CoA carboxylase beta chain PccB SWALL:PCCB_SACER (SWALL:P53003) (546 aa) fasta scores: E(): 8.9e-123, 62.5% id in 520 aa NP_788981.1 Similar to Mycobacterium tuberculosis BirA or Rv3279c or mtcy71.19c or mt3379 SWALL:P96884 (EMBL:Z92771) (266 aa) fasta scores: E(): 2.8e-16, 36.11% id in 252 aa, and to Bacillus subtilis BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-coa-carboxylase] synthetase BirA SWALL:BIRA_BACSU (SWALL:P42975) (325 aa) fasta scores: E(): 1.6e-11, 30.4% id in 250 aa NP_788982.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO4845 or SC5G8.13 SWALL:Q9KZA1 (EMBL:AL353872) (157 aa) fasta scores: E(): 2.9e-08, 41.3% id in 92 aa NP_788983.1 Similar to Mycobacterium tuberculosis phosphoribosylaminoimidazole carboxylase ATPase subunit PurK or Rv3276c or mt3376 or mtcy71.16C SWALL:PURK_MYCTU (SWALL:P96881) (429 aa) fasta scores: E(): 1.3e-21, 39.43% id in 421 aa, and to Schizosaccharomyces pombe phosphoribosylaminoimidazole carboxylase Ade6 or Min1 or Spcc1322.13 SWALL:PUR6_SCHPO (SWALL:P15567) (552 aa) fasta scores: E(): 1.5e-14, 32.15% id in 395 aa NP_788984.1 Similar to Corynebacterium ammoniagenes phosphoribosylaminoimidazole carboxylase catalytic subunit PurE SWALL:PUR6_CORAM (SWALL:Q44679) (177 aa) fasta scores: E(): 7.7e-28, 55.09% id in 167 aa, and to Streptomyces coelicolor phosphoribosylaminoimidazole carboxylase catalytic subunit PurE or SCO3059 or SCBAC19G2.14c SWALL:Q93J44 (EMBL:AL596138) (180 aa) fasta scores: E(): 3.7e-27, 54.21% id in 166 aa NP_788986.1 Similar to Streptomyces rishiriensis dTDP-4-keto-6-deoxyhexose reductase CouS SWALL:Q9F8T1 (EMBL:AF235050) (288 aa) fasta scores: E(): 4.4e-46, 48.52% id in 272 aa, and to Saccharopolyspora spinosa dTDP-4-dehydrorhamnose reductase Kre SWALL:Q93EJ9 (EMBL:AF355468) (305 aa) fasta scores: E(): 4.2e-36, 43.34% id in 293 aa NP_788987.1 Similar to Streptomyces tenebrarius AprE SWALL:Q9F5R6 (EMBL:AF306787) (332 aa) fasta scores: E(): 8.2e-88, 64.83% id in 327 aa NP_788988.1 Similar to Streptomyces antibioticus dTDP-4-keto-6-deoxyglucose 3,5-epimerase SWALL:Q9L6C5 (EMBL:AF237894) (202 aa) fasta scores: E(): 4e-34, 50% id in 192 aa NP_788989.1 Similar to Streptomyces sphaeroides NovV SWALL:Q9L9E6 (EMBL:AF170880) (297 aa) fasta scores: E(): 6.5e-76, 66.78% id in 286 aa, and to Escherichia coli glucose-1-phosphate thymidylyltransferase RffH or b3789 SWALL:RFFH_ECOLI (SWALL:P27831) (293 aa) fasta scores: E(): 6.6e-69, 59.17% id in 289 aa NP_788990.1 Similar to Mycobacterium smegmatis dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase WbbL SWALL:Q9RN50 (EMBL:AF187550) (296 aa) fasta scores: E(): 2.3e-30, 36.66% id in 270 aa NP_788991.1 Similar to Myxococcus xanthus O-antigen export system ATP-binding protein RfbB SWALL:RFBB_MYXXA (SWALL:Q50863) (437 aa) fasta scores: E(): 2.3e-30, 48.92% id in 233 aa NP_788992.1 Similar to Pseudomonas aeruginosa membrane-spanning domain Msd Wzm SWALL:P72162 (EMBL:U63722) (265 aa) fasta scores: E(): 8.6e-21, 30.68% id in 277 aa, and to Myxococcus xanthus O-antigen export system permease protein RfbA SWALL:RFBA_MYXXA (SWALL:Q50862) (260 aa) fasta scores: E(): 1.2e-15, 26.83% id in 272 aa NP_788993.1 Similar to Actinobacillus actinomycetemcomitans DNA for glycosyltransferase, lytic transglycosylase, dTDP-4-rhamnose reductase SWALL:O05379 (EMBL:AB002668) (289 aa) fasta scores: E(): 3.2e-17, 30.73% id in 257 aa NP_788995.1 Similar to Actinobacillus actinomycetemcomitans putative glycosyltransferase SWALL:Q9AQB2 (EMBL:AF213680) (234 aa) fasta scores: E(): 6.3e-16, 28.99% id in 238 aa NP_788997.1 Doubtful CDS. No significant database matches NP_788998.1 Doubtful CDS. No significant database matches NP_789005.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0758 or mt0783 or mtcy369.03 SWALL:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 8.9e-37, 31.11% id in 466 aa, and to Streptomyces coelicolor putative two component system histidine kinase SCO4021 or 2SC10A7.25 SWALL:Q9ADN6 (EMBL:AL583945) (524 aa) fasta scores: E(): 5.5e-27, 37.73% id in 265 aa NP_789006.1 Similar to Streptomyces coelicolor putative two component system response regulator SCO4020 or 2SC10A7.24 SWALL:Q9ADN7 (EMBL:AL583945) (271 aa) fasta scores: E(): 1.2e-40, 50.44% id in 226 aa NP_789007.1 Similar to Streptomyces coelicolor cold shock protein B CspB or SCO4325 or SCD12A.08 SWALL:Q9KXN2 (EMBL:AL357524) (127 aa) fasta scores: E(): 8.1e-16, 42.06% id in 126 aa, and to Pseudomonas fragi cold shock protein CapB SWALL:CAPB_PSEFR (SWALL:P80415) (69 aa) fasta scores: E(): 0.0014, 38.09% id in 63 aa NP_789009.1 Similar to Streptomyces coelicolor putative partitioning or sporulation protein SCO1772 or SCI51.12c SWALL:Q9S228 (EMBL:AL109848) (340 aa) fasta scores: E(): 9.9e-52, 57.14% id in 252 aa, and to Bacillus subtilis sporulation initiation inhibitor protein Soj SWALL:SOJ_BACSU (SWALL:P37522) (253 aa) fasta scores: E(): 2.6e-38, 46.21% id in 251 aa NP_789010.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_789011.1 CMK catalyzes the formation of (d)CDP from ATP and (d)CMP; the function of the GTP-binding domain EngA appears to be in synchronizing cellular events by interacting with multiple cellular targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide-binding affinities in the two binding domains NP_789012.1 Similar to Pseudomonas putida anthranilate synthase component I TrpE SWALL:TRPE_PSEPU (SWALL:P20579) (493 aa) fasta scores: E(): 5e-16, 29.18% id in 281 aa NP_789013.1 Similar to Streptomyces coelicolor putative ubiquinone/menaquinone methyltransferase SCO4556 or SCD16a.27c SWALL:Q9XAP8 (EMBL:AL078618) (231 aa) fasta scores: E(): 1.6e-29, 42.17% id in 230 aa, and to Escherichia coli, and Escherichia coli O157:H7 ubiquinone/menaquinone biosynthesis methyltransferase UbiE or b3833 or z5355 or ecs4763 SWALL:UBIE_ECOLI (SWALL:P27851) (251 aa) fasta scores: E(): 6.5e-23, 36.32% id in 245 aa NP_789014.1 Similar to Streptomyces coelicolor putative transferase SCO4583 or SCD20.01 SWALL:Q9F2X8 (EMBL:AL392148) (336 aa) fasta scores: E(): 3.3e-37, 38.19% id in 343 aa, and to Gluconobacter oxydans decaprenyl diphosphate synthase DdsA SWALL:O82832 (EMBL:AB006850) (315 aa) fasta scores: E(): 2.4e-23, 32.55% id in 301 aa NP_789015.1 Similar to Streptomyces coelicolor putative ferredoxin/ferredoxin-NADP reductase SCO0681 or SCF15.02 SWALL:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): 1.3e-71, 43.55% id in 450 aa, and to Rattus norvegicus NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FdxR SWALL:ADRO_RAT (SWALL:P56522) (494 aa) fasta scores: E(): 7.4e-33, 35.16% id in 455 aa NP_789016.1 Similar to Streptomyces coelicolor putative iron-siderophore binding lipoprotein SCO0494 or SCF34.13c SWALL:Q9RK12 (EMBL:AL109974) (350 aa) fasta scores: E(): 7.7e-19, 30.97% id in 339 aa, and to Corynebacterium diphtheriae DtxR/iron regulated lipoprotein precursor Irp1 SWALL:Q46023 (EMBL:U02617) (355 aa) fasta scores: E(): 1e-12, 31.02% id in 303 aa NP_789017.1 Similar to Streptomyces coelicolor putative iron-siderophore binding lipoprotein SCO0494 or SCF34.13c SWALL:Q9RK12 (EMBL:AL109974) (350 aa) fasta scores: E(): 4.2e-19, 29.82% id in 342 aa, and to Mycobacterium smegmatis FxtD SWALL:O87315 (EMBL:AF027770) (420 aa) fasta scores: E(): 2.7e-12, 31.09% id in 238 aa NP_789018.1 Similar to Escherichia coli ferric enterobactin transport ATP-binding protein FepC or b0588 SWALL:FEPC_ECOLI (SWALL:P23878) (271 aa) fasta scores: E(): 8.6e-42, 50% id in 250 aa NP_789019.1 Similar to Escherichia coli ferric enterobactin transport system permease protein FepG or b0589 SWALL:FEPG_ECOLI (SWALL:P23877) (330 aa) fasta scores: E(): 1.2e-43, 39.93% id in 323 aa NP_789020.1 Similar to Escherichia coli ferric enterobactin transport system permease protein FepD or b0590 SWALL:FEPD_ECOLI (SWALL:P23876) (334 aa) fasta scores: E(): 5.2e-33, 40% id in 305 aa NP_789021.1 Similar to Staphylococcus aureus cadmium efflux system accessory protein homolog cadC SWALL:CADF_STAAU (SWALL:P37374) (121 aa) fasta scores: E(): 3e-07, 37.89% id in 95 aa NP_789022.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine NP_789023.1 Similar to Corynebacterium glutamicum pantoate--beta-alanine ligase PanC or cgl0113 SWALL:PANC_CORGL (SWALL:Q9X713) (279 aa) fasta scores: E(): 1.5e-27, 39.59% id in 293 aa NP_789024.1 Similar to Escherichia coli cardiolipin synthetase Cls or Nov or b1249 SWALL:CLS_ECOLI (SWALL:P31071) (486 aa) fasta scores: E(): 4.9e-21, 30.64% id in 496 aa NP_789025.1 Similar to Bacillus subtilis negative regulator of genetic competence ClpC/MecB SWALL:CLPC_BACSU (SWALL:P37571) (810 aa) fasta scores: E(): 3e-152, 56.66% id in 810 aa, and to Streptomyces coelicolor putative Vlp-family ATP-binding protease SCO3373 or SCE94.24c SWALL:Q9S6T8 (EMBL:AL049628) (841 aa) fasta scores: E(): 7.6e-189, 65.87% id in 838 aa NP_789026.1 Similar to Bacillus subtilis menaquinone biosynthesis protein MenD [includes: 2-succinyl-6-hydroxy- 2,4-cyclohexadiene-1-carboxylate synthase MenD SWALL:MEND_BACSU (SWALL:P23970) (580 aa) fasta scores: E(): 3.6e-17, 28.57% id in 525 aa, and to Mycobacterium leprae putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / 2-oxoglutarate decarboxylase MenD or ML2270 SWALL:Q9CBB0 (EMBL:AL583925) (556 aa) fasta scores: E(): 1.4e-25, 32.95% id in 531 aa NP_789028.1 Similar to Escherichia coli 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA or b3930 SWALL:MENA_ECOLI (SWALL:P32166) (308 aa) fasta scores: E(): 8.9e-17, 33.45% id in 275 aa, and to Mycobacterium tuberculosis probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA or Rv0534c or mt0558 or mtcy25d10.13C SWALL:MENA_MYCTU (SWALL:O06400) (292 aa) fasta scores: E(): 2.8e-24, 40.63% id in 251 aa NP_789029.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_789030.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_789031.1 Similar to Synechocystis sp. serine esterase sll1284 SWALL:P73192 (EMBL:D90904) (204 aa) fasta scores: E(): 0.0001, 29.01% id in 193 aa NP_789032.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_789033.1 Similar to Bacillus subtilis inosine-5'-monophosphate dehydrogenase GuaB or GnaB SWALL:IMDH_BACSU (SWALL:P21879) (513 aa) fasta scores: E(): 2.1e-87, 50.92% id in 489 aa NP_789034.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_789035.1 Similar to Streptomyces coelicolor putative membrane protein SCO1829 or SCI8.14 SWALL:Q9RJ39 (EMBL:AL132644) (290 aa) fasta scores: E(): 0.37, 25.79% id in 252 aa NP_789036.1 Similar to Corynebacterium glutamicum hypothetical membrane protein Cgl2499 SWALL:BAB99892 (EMBL:AP005281) (118 aa) fasta scores: E(): 0.0015, 31.53% id in 130 aa NP_789037.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_789038.1 Similar to Bacillus subtilis ATP-dependent DNA helicase PcrA SWALL:PCRA_BACSU (SWALL:O34580) (739 aa) fasta scores: E(): 1.1e-72, 41.42% id in 758 aa NP_789040.1 Similar to Mycobacterium paratuberculosis PurN SWALL:Q9RAJ6 (EMBL:AF191543) (209 aa) fasta scores: E(): 1.5e-21, 42.39% id in 184 aa and to Escherichia coli phosphoribosylglycinamide formyltransferase PurN or b2500 SWALL:PUR3_ECOLI (SWALL:P08179) (212 aa) fasta scores: E(): 2.1e-17, 36.2% id in 174 aa NP_789041.1 Similar to Mycobacterium paratuberculosis PurH SWALL:Q9RAJ5 (EMBL:AF191543) (527 aa) fasta scores: E(): 8.2e-59, 50.46% id in 543 aa, and to Escherichia coli bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase purh or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) fasta scores: E(): 2.6e-27, 39.48% id in 547 aa NP_789043.1 Weakly similar to Streptomyces coelicolor putative integral membrane transport protein SCO0079 or SCJ11.08c SWALL:Q9RI96 (EMBL:AL109949) (407 aa) fasta scores: E(): 2.3e-19, 26.37% id in 364 aa NP_789044.1 Similar to Escherichia coli and Escherichia coli O157:H7 tRNA pseudouridine synthase B TruB or p35 or b3166 or z4527 or ecs4047 SWALL:TRUB_ECOLI (SWALL:P09171) (314 aa) fasta scores: E(): 2.2e-23, 35.24% id in 227 aa NP_789045.1 Similar to Mycobacterium tuberculosis hypothetical zinc metalloprotease Rv2869c or mt2937 or mtv003.15C SWALL:YS69_MYCTU (SWALL:O33351) (404 aa) fasta scores: E(): 8.7e-11, 34.51% id in 423 aa NP_789046.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_789047.1 Similar to Streptomyces coelicolor hypothetical protein SCO3845 or SCH69.15 SWALL:Q9XA19 (EMBL:AL079308) (515 aa) fasta scores: E(): 5.4e-22, 35.98% id in 239 aa, and to Rhizobium loti probable phosphoprotein phosphatase mlr2361 SWALL:Q98IK3 (EMBL:AP002999) (280 aa) fasta scores: E(): 1.4e-20, 36.08% id in 230 aa NP_789048.1 Weakly similar to Methanosarcina acetivorans hypothetical protein Ma1866 SWALL:Q8TPP0 (EMBL:AE010868) (613 aa) fasta scores: E(): 0.0012, 22.1% id in 579 aa NP_789049.1 Doubtful CDS. No significant database matches NP_789052.1 Similar to Myxococcus xanthus PilH SWALL:O30385 (EMBL:AF003632) (326 aa) fasta scores: E(): 1.1e-12, 33.49% id in 206 aa, and to Streptomyces coelicolor putative ABC transporter ATP-binding protein SCO3633 or SCH10.11 SWALL:Q9X8Q0 (EMBL:AL049754) (311 aa) fasta scores: E(): 2.3e-11, 29.61% id in 233 aa NP_789054.1 Similar to Corynebacterium glutamicum integrase Cgl1419 SWALL:BAB98812 (EMBL:AP005278) (304 aa) fasta scores: E(): 6.6e-16, 38.73% id in 333 aa, and to Pseudomonas aeruginosa integrase Inti1 SWALL:Q9AIL0 (EMBL:AF263519) (337 aa) fasta scores: E(): 4.4e-12, 28.75% id in 306 aa NP_789055.1 Similar to Streptomyces coelicolor hypothetical protein sco1775 sco1775 or sci51.15C SWALL:Q9S225 (EMBL:AL109848) (211 aa) fasta scores: E(): 6e-27, 46.74% id in 169 aa, and to Bacillus subtilis adp-ribose pyrophosphatase nudF SWALL:ADPP_BACSU (SWALL:P54570) (185 aa) fasta scores: E(): 1.1e-13, 33.15% id in 184 aa NP_789056.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_789057.1 Similar to Escherichia coli DNA repair protein RecN or RadB or b2616 SWALL:RECN_ECOLI (SWALL:P05824) (553 aa) fasta scores: E(): 2.9e-30, 30.23% id in 559 aa NP_789058.1 Similar to Streptomyces coelicolor probable inorganic polyphosphate/ATP-NAD kinase PpnK or SCO1781 or SCI51.21c SWALL:PPNK_STRCO (SWALL:Q9S219) (301 aa) fasta scores: E(): 1.2e-29, 39.09% id in 220 aa NP_789060.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_789061.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_789062.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_789063.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_789064.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_789065.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_789066.1 Similar to Escherichia coli O-succinylbenzoic acid--CoA ligase MenE or b2260 SWALL:MENE_ECOLI (SWALL:P37353) (451 aa) fasta scores: E(): 2.5e-10, 28.11% id in 345 aa, and to Mycobacterium tuberculosis MenE or Rv0542c or mtcy25d10.21c or mt0567 SWALL:O06408 (EMBL:Z95558) (362 aa) fasta scores: E(): 2.5e-29, 32.84% id in 338 aa NP_789067.1 Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or mt2784 or mtcy05a6.32 SWALL:IDER_MYCTU (SWALL:Q50495) (230 aa) fasta scores: E(): 6.4e-29, 42.98% id in 221 aa, and to Streptomyces lividans and Streptomyces coelicolor iron repressor DesR or DmdR1 or SCO4394 or SCD10.26 SWALL:Q54343 (EMBL:Z50049) (230 aa) fasta scores: E(): 3.8e-32, 47.23% id in 199 aa NP_789068.1 required for 70S ribosome assembly NP_789069.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_789070.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_789071.1 Similar to Escherichia coli DNA-binding protein HU-alpha HupA or b4000 or z5576 or ecs4923 SWALL:DBHA_ECOLI (SWALL:P02342) (90 aa) fasta scores: E(): 7.7e-08, 37.77% id in 90 aa, and to Streptomyces coelicolor, and Streptomyces lividans DNA-binding protein HU 1 Hup1 or Hup or SCO2950 or SCE59.09 SWALL:DBH1_STRCO (SWALL:O06447) (93 aa) fasta scores: E(): 5.1e-13, 50.54% id in 91 aa NP_789072.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0102 or mt0111 or mtcy251.21 SWALL:Y102_MYCTU (SWALL:Q10897) (661 aa) fasta scores: E(): 8.5e-38, 31.79% id in 478 aa, and to Streptomyces coelicolor putative integral membrane protein SCO1215 or 2SCG58.15 SWALL:Q9FC98 (EMBL:AL391017) (316 aa) fasta scores: E(): 3.3e-37, 40.13% id in 304 aa NP_789073.1 Similar to Anabaena sp. hypothetical protein Alr4398 SWALL:Q8YP09 (EMBL:AP003596) (1075 aa) fasta scores: E(): 9.6e-17, 26.54% id in 584 aa, and to Drosophila melanogaster IswI protein or cg8625 SWALL:ISWI_DROME (SWALL:Q24368) (1027 aa) fasta scores: E(): 2.3e-15, 26.16% id in 474 aa NP_789074.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_789076.1 Similar to Escherichia coli mannose-6-phosphate isomerase ManA or Pmi or b1613 SWALL:MANA_ECOLI (SWALL:P00946) (391 aa) fasta scores: E(): 2.9e-15, 30.23% id in 387 aa, and to Streptomyces coelicolor mannose-6-phosphate isomerase ManA or SCO3025 or SCE34.06c SWALL:Q9KZL9 (EMBL:AL353862) (383 aa) fasta scores: E(): 1.5e-22, 34.36% id in 323 aa NP_789077.1 Similar to Streptomyces griseocarneus WhiB-STV protein SWALL:Q06387 (EMBL:X68708) (87 aa) fasta scores: E(): 1.6e-20, 80% id in 70 aa, and to Streptomyces coelicolor regulatory protein WhiB or SCO3034 or SCE34.15C SWALL:Q53963 (EMBL:X62287) (87 aa) fasta scores: E(): 1.6e-20, 80% id in 70 aa NP_789078.1 Similar to Streptomyces aureofaciens transmembrane protein WhiB2 SWALL:Q53785 (EMBL:L22864) (1219 aa) fasta scores: E(): 1.5e-06, 21.76% id in 896 aa, and to Streptomyces coelicolor putative integral membrane protein SCO3033 or SCE34.14c SWALL:Q9KZL1 (EMBL:AL353862) (1268 aa) fasta scores: E(): 2e-06, 24.06% id in 939 aa NP_789079.1 Similar to Streptomyces coelicolor putative secreted protein SCO3032 or SCE34.13c SWALL:Q9KZL2 (EMBL:AL353862) (506 aa) fasta scores: E(): 0.01, 24.83% id in 294 aa NP_789080.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells NP_789081.1 Similar to Corynebacterium glutamicum predicted amidophosphoribosyltransferases Cgl0757 SWALL:BAB98150 (EMBL:AP005276) (196 aa) fasta scores: E(): 4.4e-06, 23.98% id in 196 aa, and to Deinococcus radiodurans competence protein ComF, putative dr1389 SWALL:Q9RUJ7 (EMBL:AE001984) (219 aa) fasta scores: E(): 2.2e-05, 27.17% id in 195 aa NP_789082.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_789083.1 Doubtful CDS. No significant database matches NP_789085.1 Similar to Bacillus subtilis sporulation initiation inhibitor protein SoJ SWALL:SOJ_BACSU (SWALL:P37522) (253 aa) fasta scores: E(): 0.00051, 30.88% id in 136 aa NP_789086.1 No significant database matches. Frameshift at potentially variable G(11) tract after aa 70 NP_789087.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine NP_789088.1 Similar to Streptomyces coelicolor putative peptide transport system secreted peptide-binding protein SCO5117 or SC9E12.02 SWALL:Q9F353 (EMBL:AL391751) (544 aa) fasta scores: E(): 1.2e-51, 33.57% id in 551 aa NP_789089.1 Similar to Streptomyces coelicolor putative peptide transport system secreted peptide-binding protein SCO5117 or SC9E12.02 SWALL:Q9F353 (EMBL:AL391751) (544 aa) fasta scores: E(): 3.3e-48, 33.39% id in 512 aa NP_789090.1 Similar to Rhizobium meliloti hypothetical transmembrane protein smc00963 r00889 or smc00963 SWALL:Q92RI2 (EMBL:AL591785) (201 aa) fasta scores: E(): 2.3e-12, 34.23% id in 184 aa NP_789091.1 Similar to Deinococcus radiodurans ABC transporter, ATP-binding protein dr2469 SWALL:Q9RRL9 (EMBL:AE002076) (226 aa) fasta scores: E(): 3.2e-27, 42.98% id in 221 aa NP_789092.1 Similar to Streptomyces coelicolor putative peptide transport system integral membrane protein SCO5118 or SC9E12.03 SWALL:Q9F352 (EMBL:AL391751) (307 aa) fasta scores: E(): 6.3e-45, 42.15% id in 306 aa, and to Bacillus subtilis oligopeptide transport system permease protein OppB SWALL:OPPB_BACSU (SWALL:P24138) (311 aa) fasta scores: E(): 2.4e-28, 34.07% id in 314 aa NP_789093.1 Similar to Corynebacterium glutamicum ABC-type transporter, permease components cgl1992 SWALL:BAB99385 (EMBL:AP005280) (333 aa) fasta scores: E(): 2.3e-50, 45.77% id in 308 aa, and to Bacillus subtilis oligopeptide transport system permease protein OppC or Spo0KC SWALL:OPPC_BACSU (SWALL:P24139) (305 aa) fasta scores: E(): 6.1e-29, 31.77% id in 299 aa NP_789094.1 Similar to Mycobacterium tuberculosis putative peptide ABC transporter ATP-binding protein Rv3663c or mtv025.011c or mt3764 SWALL:O69631 (EMBL:AL022121) (548 aa) fasta scores: E(): 2e-88, 52.67% id in 543 aa NP_789095.1 Doubtful CDS. No significant database matches NP_789096.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_789097.1 forms a direct contact with the tRNA during translation NP_789098.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_789099.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_789100.1 No significant database matches. Has possible N-terminal secretion signal sequence and 3 possible membrane spanning regions in the C-terminal portion. Similar to CDS TW161 - TW157 residues 8-275 identical to TW161 residues 7-274, though not similar at sequence level TW161 C-terminal portion also contains 3 possible membrane spanning regions. Region following identity with TW161 is an array of small repeats. NP_789101.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_789102.1 Similar to Escherichia coli 4-diphosphocytidyl-2-c-methyl-D-erythritol kinase IspE or Ipk or b1208 or z1979 or ecs1713 SWALL:ISPE_ECOLI (SWALL:P24209) (283 aa) fasta scores: E(): 7.7e-07, 28.95% id in 221 aa, and to Streptomyces coelicolor 4-diphosphocytidyl-2-c-methyl-D-erythritol kinase IspE or SCO3148 or SCE66.27c SWALL:ISPE_STRCO (SWALL:Q9K3R6) (299 aa) fasta scores: E(): 5.9e-21, 39.07% id in 238 aa. Note possible alternative translational start sites. NP_789103.1 Similar to Corynebacterium glutamicum uncharacterized membrane proteins cgl2282 SWALL:BAB99675 (EMBL:AP005281) (264 aa) fasta scores: E(): 2.1e-24, 43.16% id in 278 aa NP_789104.1 No significant database matches. Has possible N-terminal secretion signal sequence and 3 possible membrane spanning regions in the C-terminal portion. Similar to CDS TW157 - TW161 residues 7-274 identical to TW157 residues 8-275, though not similar at sequence level TW157 C-terminal portion also contains 3 possible membrane spanning regions. NP_789105.1 Similar to Escherichia coli transport ATP-binding protein CydC or MdrA or MdrH or SurB or b0886 SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): 4.8e-32, 27.92% id in 573 aa NP_789106.1 Similar to Clostridium perfringens probable ABC transporter cpe0226 SWALL:Q8XNV6 (EMBL:AP003185) (576 aa) fasta scores: E(): 2.7e-35, 26.56% id in 576 aa NP_789107.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO2196 or SC5F7.05 or SC3H12.04 SWALL:Q9S2P0 (EMBL:AL096872) (234 aa) fasta scores: E(): 5.7e-15, 31.89% id in 232 aa NP_789108.1 Similar to Streptomyces coelicolor putative serine/threonine protein kinase SCO1724 or SCI11.13 SWALL:Q9S2A6 (EMBL:AL096849) (550 aa) fasta scores: E(): 0.0015, 30.3% id in 165 aa, and to Amycolatopsis mediterranei serine/threonine kinase PkmA SWALL:Q9KK90 (EMBL:AF135382) (589 aa) fasta scores: E(): 0.0043, 25.59% id in 168 aa NP_789109.1 Similar to Caulobacter crescentus elongation factor TU family protein cc0741 SWALL:Q9AA65 (EMBL:AE005749) (610 aa) fasta scores: E(): 4e-83, 43.18% id in 616 aa, and to Streptomyces coelicolor putative GTP-binding protein SCO5111 or SCBAC31E11.07 SWALL:Q93IU4 (EMBL:AL596043) (635 aa) fasta scores: E(): 8.9e-80, 56.85% id in 635 aa NP_789110.1 Has C-terminal similarity to proteins of undefined function. Similar to Streptococcus pyogenes hypothetical protein Spym18_1743 SWALL:AAL98271 (EMBL:AE010084) (153 aa) fasta scores: E(): 1.6e-10, 40% id in 140 aa NP_789111.1 Localised similarity to proteins of unknown function. C-terminal similar to Thermoanaerobacter tengcongensis acetyltransferases RimI3 or tte0537 SWALL:Q8RC99 (EMBL:AE013024) (149 aa) fasta scores: E(): 5e-10, 37.24% id in 145 aa. N-termional similar to Corynebacterium glutamicum inactive homologs of metal-dependent proteases, putative molecular chaperones cgl0592 SWALL:BAB97985 (EMBL:AP005275) (225 aa) fasta scores: E(): 0.00017, 39.62% id in 106 aa NP_789112.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_789113.1 Similar to Streptomyces coelicolor hypothetical protein SCO3406 or SCE9.13c SWALL:Q9X8I6 (EMBL:AL049841) (352 aa) fasta scores: E(): 2.6e-11, 32.66% id in 401 aa NP_789114.1 Similar to Salmonella typhimurium hypoxanthine phosphoribosyltransferase Hpt or Stm0170 SWALL:HPRT_SALTY (SWALL:O33799) (178 aa) fasta scores: E(): 7.7e-25, 46.01% id in 163 aa, and to Streptomyces coelicolor putative hypoxanthine phosphoribosyltransferase HprT or SCO3405 or SCE9.12c SWALL:Q9X8I5 (EMBL:AL049841) (187 aa) fasta scores: E(): 7.9e-35, 54.81% id in 166 aa NP_789115.1 Similar to Streptococcus pneumoniae cell division protein FtsH or sp0013 SWALL:FTSH_STRPN (SWALL:O69076) (652 aa) fasta scores: E(): 2.5e-86, 54.38% id in 502 aa, and to Streptomyces coelicolor cell division protein FtsH homolog FtsH2 or SCO3404 or SCE9.11c SWALL:Q9X8I4 (EMBL:AL049841) (668 aa) fasta scores: E(): 4.5e-119, 55.12% id in 664 aa NP_789116.1 Similar to Bacillus subtilis GTP cyclohydrolase I FolE or MtrA SWALL:GCH1_BACSU (SWALL:P19465) (190 aa) fasta scores: E(): 1.9e-12, 33.53% id in 167 aa, and to Bacillus halodurans GTP cyclohydrolase I FolE or MtrA or bh1646 SWALL:GCH1_BACHD (SWALL:Q9KCC7) (188 aa) fasta scores: E(): 2.6e-14, 32.25% id in 186 aa NP_789117.1 Similar to Bacillus subtilis dihydropteroate synthase Sul SWALL:DHPS_BACSU (SWALL:P28822) (285 aa) fasta scores: E(): 8.7e-28, 40.61% id in 261 aa, and to Streptomyces coelicolor putative dihydropteroate synthase FolP or SCO3398 or SCE9.05 SWALL:Q9X8H8 (EMBL:AL049841) (288 aa) fasta scores: E(): 1.7e-38, 46.26% id in 268 aa NP_789119.1 Similar to Lactococcus lactis NisF protein NisF SWALL:Q48635 (EMBL:Z29363) (225 aa) fasta scores: E(): 2.3e-15, 32.57% id in 221 aa NP_789121.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_789122.1 Similar to Escherichia coli riboflavin biosynthesis protein RibF [includes: riboflavin kinase] or b0025 or z0029 or ecs0028 SWALL:RIBF_ECOLI (SWALL:P08391) (313 aa) fasta scores: E(): 8.3e-30, 35.33% id in 317 aa NP_789125.1 Similar to Aeromonas hydrophila type 4 prepilin-like proteins leader peptide processing enzyme [includes: leader peptidase tapD] SWALL:LEP4_AERHY (SWALL:P45794) (290 aa) fasta scores: E(): 1.5e-05, 29.44% id in 197 aa, and to Escherichia coli leader peptidase HopD SWALL:HOPD_ECOLI (SWALL:O68932) (155 aa) fasta scores: E(): 0.0017, 32.7% id in 159 aa NP_789127.1 Similar to Streptomyces griseus ferredoxin SWALL:FER_STRGR (SWALL:P13279) (105 aa) fasta scores: E(): 1.8e-33, 79.2% id in 101 aa NP_789128.1 Weakly similar to Streptomyces coelicolor putative integral membrane protein SCO1752 or 2SCI34.05 SWALL:Q9EWX4 (EMBL:AL445403) (396 aa) fasta scores: E(): 4.1e-05, 24.72% id in 364 aa NP_789129.1 No significant database matches. Possible coiled-coil region at residues 42-80. NP_789130.1 Similar to Streptomyces mycarofaciens O-methyltransferase MdmC SWALL:MDMC_STRMY (SWALL:Q00719) (221 aa) fasta scores: E(): 8e-05, 28.57% id in 175 aa NP_789131.1 N-terminus similar to that of Caulobacter crescentus hypothetical protein Cc2002 SWALL:Q9A6T1 (EMBL:AE005873) (200 aa) fasta scores: E(): 5.2, 31.91% id in 47 aa NP_789134.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_789135.1 Similar to Staphylococcus aureus ATP-dependent DNA helicase RecG SWALL:RECG_STAAU (SWALL:O50581) (686 aa) fasta scores: E(): 3.9e-62, 32.43% id in 666 aa NP_789136.1 Similar to Escherichia coli phosphopantetheine adenylyltransferase CoaD or KdtB or b3634 or z5058 or ecs4509 SWALL:COAD_ECOLI (SWALL:P23875) (159 aa) fasta scores: E(): 3.8e-06, 33.13% id in 169 aa NP_789137.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO3849 or SCH69.19c SWALL:Q9XA15 (EMBL:AL079308) (253 aa) fasta scores: E(): 9.6e-09, 25.6% id in 250 aa NP_789138.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_789139.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_789140.1 Similar to Pseudomonas aeruginosa leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor BraC or pa1074 SWALL:BRAC_PSEAE (SWALL:P21175) (373 aa) fasta scores: E(): 3.2e-22, 28.78% id in 337 aa NP_789141.1 Similar to Escherichia coli high-affinity branched-chain amino acid transport system permease protein LivH or b3457 or z4827 or ecs4304 SWALL:LIVH_ECOLI (SWALL:P08340) (308 aa) fasta scores: E(): 1.1e-30, 42.05% id in 302 aa NP_789142.1 Similar to Escherichia coli high-affinity branched-chain amino acid transport system permease protein LivM or b3456 SWALL:LIVM_ECOLI (SWALL:P22729) (425 aa) fasta scores: E(): 2.9e-14, 36.19% id in 326 aa NP_789143.1 Similar to Escherichia coli high-affinity branched-chain amino acid transport ATP-binding protein LivG or b3455 or z4825 or ecs4302 SWALL:LIVG_ECOLI (SWALL:P22730) (255 aa) fasta scores: E(): 4.7e-36, 47.43% id in 253 aa NP_789144.1 Similar to Escherichia coli high-affinity branched-chain amino acid transport ATP-binding protein LivF or b3454 SWALL:LIVF_ECOLI (SWALL:P22731) (237 aa) fasta scores: E(): 1.4e-33, 52.42% id in 227 aa NP_789145.1 Similar to Escherichia coli cell division protein FtsY or b3464 SWALL:FTSY_ECOLI (SWALL:P10121) (497 aa) fasta scores: E(): 4.8e-30, 47.32% id in 224 aa NP_789146.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_789147.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_789148.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_789149.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_789150.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_789151.1 Similar to Escherichia coli 30s ribosomal protein S19 RpsS or b3316 or z4687 or ecs4181 SWALL:RS19_ECOLI (SWALL:P02375) (91 aa) fasta scores: E(): 6.9e-26, 67.39% id in 92 aa NP_789152.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_789153.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_789154.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_789155.1 one of the stabilizing components for the large ribosomal subunit NP_789156.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_789157.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_789158.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_789159.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_789160.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_789161.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_789162.1 binds 5S rRNA along with protein L5 and L25 NP_789163.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_789164.1 late assembly protein NP_789165.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_789166.1 Similar to Xanthomonas campestris adenylate kinase Adk or Xcc3291 SWALL:AAM42561 (EMBL:AE012446) (187 aa) fasta scores: E(): 3.3e-21, 37.96% id in 187 aa, and to Homo sapiens adenylate kinase isoenzyme 1 Ak1 SWALL:KAD1_HUMAN (SWALL:P00568) (194 aa) fasta scores: E(): 3.7e-14, 32.78% id in 183 aa NP_789167.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate NP_789168.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_789169.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_789170.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_789171.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_789172.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_789173.1 is a component of the macrolide binding site in the peptidyl transferase center NP_789174.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_789175.1 Similar to Mycobacterium tuberculosis Mrp protein homolog or rv1229c or mt1267 or mtci61.12c or mtv006.01C SWALL:MRP_MYCTU (SWALL:O33225) (381 aa) fasta scores: E(): 1.2e-45, 43.83% id in 365 aa NP_789176.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1231c or mtv006.03c or mt1269 SWALL:O86314 (EMBL:Z98260) (180 aa) fasta scores: E(): 1.4e-09, 39.25% id in 135 aa NP_789177.1 Similar to Streptomyces coelicolor hypothetical protein SCO5154 or SCP8.17c SWALL:Q9FBK4 (EMBL:AL390975) (433 aa) fasta scores: E(): 6.5e-37, 38.06% id in 423 aa NP_789178.1 Similar to Streptomyces coelicolor Xaa-Pro aminopeptidase I PepP1 or SCO3970 or SCBAC25e3.07c SWALL:AMP1_STRCO (SWALL:Q05813) (490 aa) fasta scores: E(): 6.8e-55, 43.76% id in 409 aa, and to Escherichia coli Xaa-Pro aminopeptidase PepP or b2908 SWALL:AMPP_ECOLI (SWALL:P15034) (440 aa) fasta scores: E(): 1.9e-26, 35.63% id in 275 aa NP_789180.1 Similar to Corynebacterium glutamicum hypothetical protein Cgl0772 SWALL:BAB98165 (EMBL:AP005276) (75 aa) fasta scores: E(): 0.0016, 34.72% id in 72 aa; No significant database matches NP_789181.1 Similar to Streptomyces coelicolor putative ATP-dependent DNA helicase SCO5183 or 2SC3B6.07 SWALL:Q9FCK5 (EMBL:AL390968) (1159 aa) fasta scores: E(): 2.7e-07, 24.49% id in 1139 aa NP_789182.1 Similar to Streptomyces coelicolor putative ATP-dependent DNA helicase SCO5184 or 2SC3B6.08 SWALL:Q9FCK4 (EMBL:AL390968) (1222 aa) fasta scores: E(): 9.9e-16, 26.61% id in 1161 aa, and to Escherichia coli DNA helicase II UvrB or MutU or PdeB or Rad or Recl or b3813 SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): 2.8e-09, 24.25% id in 800 aa NP_789183.1 Weakly similar to Escherichia coli macrolide 2'-phosphotransferase I MphA SWALL:Q47396 (EMBL:D16251) (301 aa) fasta scores: E(): 1.4e-07, 26.1% id in 226 aa NP_789184.1 Similar to Streptomyces coelicolor putative ATP-dependent DNA helicase SCO5188 or 2SC3B6.12 SWALL:Q9FCK0 (EMBL:AL390968) (785 aa) fasta scores: E(): 2.7e-40, 35.14% id in 606 aa, and to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or Recl or b3813 SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): 1.5e-19, 25.47% id in 636 aa NP_789185.1 Similar to Streptomyces coelicolor hypothetical protein SCO5199 or 2SC3B6.23c SWALL:Q9FCI9 (EMBL:AL390968) (487 aa) fasta scores: E(): 1.7e-38, 32.7% id in 425 aa NP_789186.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_789187.1 Similar to Streptomyces coelicolor hypothetical protein SCO1749 or 2SCI34.02 SWALL:Q9EWX7 (EMBL:AL445403) (146 aa) fasta scores: E(): 3.5e-07, 35.33% id in 133 aa NP_789188.1 Similar to Bacillus subtilis minicell-associated protein DivIVA SWALL:P71021 (EMBL:U60901) (164 aa) fasta scores: E(): 0.031, 27.32% id in 161 aa NP_789189.1 Similar to Staphylococcus aureus lipoprotein signal peptidase LspA or Lsp SWALL:LSPA_STAAU (SWALL:P31024) (163 aa) fasta scores: E(): 1.9e-07, 35.82% id in 134 aa, and to Bacillus halodurans lipoprotein signal peptidase LspA or Lsp or bh2543 SWALL:LSPA_BACHD (SWALL:Q9K9V2) (156 aa) fasta scores: E(): 3.5e-09, 36.48% id in 148 aa NP_789190.1 Similar to Streptomyces coelicolor putative ribosomal large subunit pseudouridine synthase SCO2073 or SC4A10.06c SWALL:Q9S2X8 (EMBL:AL109663) (314 aa) fasta scores: E(): 2.5e-42, 49.55% id in 224 aa NP_789191.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_789192.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO0892 or SCM1.25c SWALL:Q9RD18 (EMBL:AL133422) (316 aa) fasta scores: E(): 8.5e-37, 42.12% id in 292 aa NP_789193.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_789194.1 Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2182c or mtv021.15c or mt2237 SWALL:O53516 (EMBL:AL021957) (247 aa) fasta scores: E(): 6.9e-07, 26.92% id in 208 aa NP_789195.1 Similar to Bacillus subtilis glycerol-3-phosphate dehydrogenase GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 1.2e-31, 36.94% id in 314 aa, and to Streptomyces coelicolor glycerol-3-phosphate dehydrogenase GpsA or SCO5559 or SC7A1.03 SWALL:GPDA_STRCO (SWALL:Q9ZBS0) (336 aa) fasta scores: E(): 1.6e-39, 43.59% id in 312 aa NP_789196.1 Similar to Escherichia coli, and Escherichia coli O157:H7 D-alanine--D-alanine ligase A DdlA or b0381 or z0477 or ecs0431 SWALL:DDLA_ECOLI (SWALL:P23844) (364 aa) fasta scores: E(): 5.1e-32, 32.86% id in 353 aa NP_789197.1 Weakly similar to Streptomyces coelicolor hypothetical protein SCO3628 or SCH10.06c SWALL:Q9X8P5 (EMBL:AL049754) (163 aa) fasta scores: E(): 3.8e-07, 32.79% id in 125 aa NP_789198.1 Similar to Bacillus subtilis lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex BfmB SWALL:ODB2_BACSU (SWALL:P37942) (424 aa) fasta scores: E(): 1.6e-33, 34.64% id in 459 aa, and to Streptomyces seoulensis dihydrolipoamide acetyltransferase PdhB SWALL:Q9Z6I4 (EMBL:AF047034) (612 aa) fasta scores: E(): 1.3e-48, 41.3% id in 477 aa NP_789199.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_789200.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_789201.1 Similar to Chlamydia pneumoniae glycyl-tRNA synthetase GlyQS or GlyQ or cpn0946 or cp0913 SWALL:SYG_CHLPN (SWALL:Q9Z6W0) (1010 aa) fasta scores: E(): 8.9e-78, 30.52% id in 1055 aa, and to Arabidopsis thaliana aminoacyl-t-RNA synthetase precursor Edd1 SWALL:O23150 (EMBL:AJ003069) (1067 aa) fasta scores: E(): 1.1e-100, 39.47% id in 1021 aa NP_789202.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released NP_789203.1 Similar to Mycobacterium tuberculosis hypothetical 43.4 kDa protein Rv3712 or mtv025.060 or mt3815 SWALL:O69679 (EMBL:AL022121) (413 aa) fasta scores: E(): 1.4e-18, 31.18% id in 388 aa. Weak similarity to murein ligases. NP_789204.1 Weakly similar to many eg. Staphylococcus aureus hypothetical protein sav1891 sav1891 or sa1707 or mw1832 SWALL:Q99SZ5 (EMBL:AP003363) (243 aa) fasta scores: E(): 9e-10, 25.12% id in 203 aa NP_789205.1 Provides the d-alanine required for cell wall biosynthesis. Similar to Streptomyces coelicolor alanine racemase Alr or SCO4745 or SC6G4.23 SWALL:ALR_STRCO (SWALL:O86786) (391 aa) fasta scores: E(): 1.2e-19, 29.5% id in 400 aa, and to Lactobacillus plantarum alanine racemase Alr SWALL:ALR_LACPL (SWALL:O08445) (375 aa) fasta scores: E(): 0.0001, 24.13% id in 377 aa NP_789206.1 Provides the d-alanine required for cell wall biosynthesis. Similar to the C-terminal region of alanine racemases eg. Corynebacterium glutamicum alanine racemase Alr or cgl0588 SWALL:BAB97981 (EMBL:AY077456) (361 aa) fasta scores: E(): 1.8e-07, 34.82% id in 112 aa. NP_789207.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_789208.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_789209.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_789210.1 Similar to Streptomyces coelicolor hypothetical protein SCO5855 or SC9B10.22c SWALL:O50529 (EMBL:AL009204) (352 aa) fasta scores: E(): 0.00048, 28.57% id in 350 aa NP_789211.1 Similar to Streptomyces coelicolor hypothetical protein SCO5864 or SC2E9.05 SWALL:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 8.6e-13, 49.48% id in 97 aa NP_789212.1 Similar to Mycobacterium leprae u1764i ml1027 putative membrane protein SWALL:Q49991 (EMBL:U15181) (157 aa) fasta scores: E(): 2.4e-10, 33.76% id in 154 aa NP_789213.1 Similar to Streptomyces coelicolor deoxyuridine 5'-triphosphate nucleotidohydrolase Dut or SCO5868 or SC2E9.09 SWALL:DUT_STRCO (SWALL:O54134) (183 aa) fasta scores: E(): 5.6e-21, 50% id in 130 aa NP_789214.1 Weak and partial similarity to Streptomyces coelicolor hypothetical protein SCO5869 or SC2E9.10 SWALL:O54135 (EMBL:AL021530) (250 aa) fasta scores: E(): 2.5e-19, 40% id in 175 aa NP_789215.1 Similar to Streptomyces coelicolor hypothetical protein sSCO5874 or SC2E9.15 SWALL:O54140 (EMBL:AL021530) (272 aa) fasta scores: E(): 7.4e-13, 28.72% id in 188 aa NP_789216.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_789217.1 Similar to Escherichia coli trigger factor Tig or b0436 or z0541 or ecs0490 SWALL:TIG_ECOLI (SWALL:P22257) (432 aa) fasta scores: E(): 2.8e-12, 25.55% id in 407 aa, and to Streptomyces coelicolor trigger factor Tig or SCO2620 or SCC80.05c SWALL:Q9F314 (EMBL:AL442143) (468 aa) fasta scores: E(): 6.4e-24, 30.9% id in 453 aa NP_789219.1 Similar to Streptomyces coelicolor ATP-dependent Clp protease proteolytic subunit 1 ClpP1 or SCO2619 or SCC80.04c SWALL:CLP1_STRCO (SWALL:Q9F315) (219 aa) fasta scores: E(): 5.1e-39, 58.82% id in 170 aa NP_789220.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_789221.1 binds and unfolds substrates as part of the ClpXP protease NP_789222.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_789223.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_789224.1 Similar to Lactobacillus casei folylpolyglutamate synthase Fgs SWALL:FOLC_LACCA (SWALL:P15925) (428 aa) fasta scores: E(): 6.4e-22, 33.23% id in 343 aa, and to Corynebacterium glutamicum folylpolyglutamate synthase cgl2375 SWALL:BAB99768 (EMBL:AP005281) (458 aa) fasta scores: E(): 5.6e-47, 37.14% id in 455 aa NP_789225.1 Similar to Streptomyces coelicolor putative membrane protein SCO2613 or SCC88.24c SWALL:Q9L1G5 (EMBL:AL139298) (118 aa) fasta scores: E(): 0.83, 28.84% id in 104 aa NP_789226.1 Similar to Streptomyces coelicolor nucleoside diphosphate kinase Ndk or SCO2612 or SCC88.23c SWALL:NDK_STRCO (SWALL:P50589) (137 aa) fasta scores: E(): 5.6e-23, 48.52% id in 136 aa, and to Dictyostelium discoideum nucleoside diphosphate kinase, cytosolic NdkB or NdkC or Gip17 SWALL:NDKC_DICDI (SWALL:P22887) (155 aa) fasta scores: E(): 3e-24, 48.5% id in 134 aa NP_789227.1 Similar to Escherichia coli ribonuclease E Rne or Ams or Hmp1 or b1084 SWALL:RNE_ECOLI (SWALL:P21513) (1061 aa) fasta scores: E(): 9.7e-38, 36.25% id in 411 aa, and to Streptomyces coelicolor hypothetical protein SCO2599 or SCC88.10c SWALL:Q9L1H8 (EMBL:AL139298) (1340 aa) fasta scores: E(): 1.6e-58, 44.28% id in 560 aa NP_789228.1 Similar to Mycobacterium tuberculosis 50s ribosomal protein L21 RplU or Rv2442c or mt2518 or mtcy428.04 SWALL:RL21_MYCTU (SWALL:P71907) (104 aa) fasta scores: E(): 9.8e-15, 50.5% id in 99 aa, and to Escherichia coli 50s ribosomal protein L21 RplU or b3186 or z4549 or ecs4065 SWALL:RL21_ECOLI (SWALL:P02422) (103 aa) fasta scores: E(): 0.00059, 29.7% id in 101 aa NP_789229.1 involved in the peptidyltransferase reaction during translation NP_789230.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_789232.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_789234.1 C-terminal portion similar to that of Corynebacterium glutamicum hypothetical protein Cgl1342 cgl1342 SWALL:BAB98735 (EMBL:AP005278) (285 aa) fasta scores: E(): 2.1e-09, 40% id in 120 aa NP_789235.1 Similar to Streptococcus pneumoniae R6 hypothetical 37.7 kDa protein spr0510 SWALL:AAK99314 (EMBL:AE008430) (333 aa) fasta scores: E(): 4.6e-13, 26.08% id in 322 aa NP_789236.1 Similar to Bacillus subtilis methylated-DNA--protein-cysteine methyltransferase Ogt or Dat or Dat1 SWALL:OGT_BACSU (SWALL:P11742) (165 aa) fasta scores: E(): 4.4e-12, 44.62% id in 121 aa NP_789237.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_789238.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein NP_789239.1 Similar to Escherichia coli signal recognition particle protein Ffh or b2610 or z3904 or ecs3473 SWALL:SR54_ECOLI (SWALL:P07019) (453 aa) fasta scores: E(): 1.1e-33, 34.89% id in 447 aa NP_789240.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_789241.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2908c or mt2976 or mtcy274.40C SWALL:YT08_MYCTU (SWALL:Q10826) (80 aa) fasta scores: E(): 1.4e-07, 46.91% id in 81 aa NP_789242.1 Similar to Mycobacterium tuberculosis probable 16s rRNA processing protein RimM or Rv2907c or mt2975 or mtcy274.38C SWALL:RIMM_MYCTU (SWALL:Q10824) (176 aa) fasta scores: E(): 1.5e-10, 30.72% id in 179 aa NP_789243.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_789244.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_789245.1 Similar to Bacillus subtilis signal peptidase I SipS SWALL:LEPS_BACSU (SWALL:P28628) (184 aa) fasta scores: E(): 1.5e-06, 29.64% id in 199 aa, and to Streptomyces lividans signal peptidase I sipX SWALL:O86869 (EMBL:Z86111) (320 aa) fasta scores: E(): 8.4e-30, 46% id in 213 aa NP_789246.1 Doubtful CDS. No significant database matches NP_789247.1 Similar to Thermotoga maritima hypothetical protein Tm0253 SWALL:Y253_THEMA (SWALL:Q9WY95) (108 aa) fasta scores: E(): 9.1e-09, 41.5% id in 106 aa NP_789248.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2897c or mt2965 or mtcy274.28C SWALL:YS97_MYCTU (SWALL:Q10818) (503 aa) fasta scores: E(): 1.9e-61, 43.77% id in 514 aa NP_789249.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2896c or mt2964 or mtcy274.27C SWALL:YS96_MYCTU (SWALL:Q10817) (389 aa) fasta scores: E(): 9.6e-28, 40.07% id in 272 aa, and to Haemophilus influenzae Smf protein or DprA or hi0985 SWALL:SMF_HAEIN (SWALL:P43862) (373 aa) fasta scores: E(): 8e-16, 30.63% id in 284 aa NP_789250.1 Similar to Mycobacterium tuberculosis probable integrase/recombinase XerC or Rv2894c or mt2962 or mtcy274.25C SWALL:XERC_MYCTU (SWALL:Q10815) (298 aa) fasta scores: E(): 2.2e-35, 43.18% id in 301 aa, and to Pseudomonas fluorescens Sss/XerC protein SWALL:O05324 (EMBL:Y12268) (299 aa) fasta scores: E(): 4.6e-29, 36.11% id in 288 aa NP_789251.1 Doubtful CDS. No significant database matches NP_789253.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_789254.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_789255.1 Catalyzes the phosphorylation of UMP to UDP NP_789256.1 Similar to Pseudomonas aeruginosa ribosome recycling factor Frr or pa3653 SWALL:RRF_PSEAE (SWALL:O82853) (185 aa) fasta scores: E(): 9.4e-15, 35.59% id in 177 aa, and to Streptomyces coelicolor ribosome recycling factor Frr or SCO5627 or SC6A9.40C SWALL:RRF_STRCO (SWALL:O86770) (185 aa) fasta scores: E(): 2.1e-21, 42.45% id in 179 aa NP_789257.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO5628 or SC6A9.39C SWALL:O86769 (EMBL:AL031035) (391 aa) fasta scores: E(): 1.7e-18, 35.44% id in 268 aa, and to Escherichia coli phosphatidate cytidylyltransferase CdsA or Cds or b0175 or z0186 or ecs0177 SWALL:CDSA_ECOLI (SWALL:P06466) (249 aa) fasta scores: E(): 1.5e-15, 33.85% id in 192 aa NP_789258.1 Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 6.8e-14, 28.96% id in 290 aa, and to Streptomyces coelicolor putative exonuclease SCO6341 or SC3A7.09 SWALL:O86610 (EMBL:AL031155) (259 aa) fasta scores: E(): 6.4e-24, 40.07% id in 272 aa NP_789260.1 Similar to Streptomyces coelicolor putative secreted protein SCO5029 or SCK7.02 SWALL:Q9FBP7 (EMBL:AL391754) (238 aa) fasta scores: E(): 1.2e-14, 47.36% id in 114 aa NP_789261.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_789263.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_789264.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_789265.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_789266.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_789267.1 Similar to Escherichia coli peptide chain release factor 1 PrfA or SueB or Uar or b1211 or z1982 or ecs1716 SWALL:RF1_ECOLI (SWALL:P07011) (360 aa) fasta scores: E(): 1.3e-47, 44.41% id in 322 aa, and to Streptomyces coelicolor peptide chain release factor 1 PrfA or SCO5360 or 2SC6G5.04 SWALL:RF1_STRCO (SWALL:Q9K4E4) (358 aa) fasta scores: E(): 3.2e-74, 55.11% id in 352 aa NP_789268.1 Similar to Escherichia coli protein methyltransferase HemK or b1212 SWALL:HEMK_ECOLI (SWALL:P37186) (277 aa) fasta scores: E(): 1.1e-18, 30.03% id in 273 aa NP_789269.1 Similar to Streptomyces coelicolor hypothetical protein SCO5362 or 2SC6G5.06 SWALL:Q9K4E2 (EMBL:AL359152) (215 aa) fasta scores: E(): 9.1e-23, 44.44% id in 189 aa NP_789270.1 Similar to Mycobacterium tuberculosis putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe or rv1302 or mt1341 or mtcy373.22 SWALL:RFE_MYCTU (SWALL:Q10606) (404 aa) fasta scores: E(): 3.8e-34, 34.98% id in 363 aa, and to Yersinia enterocolitica WbcO protein SWALL:Q56918 (EMBL:Z47767) (341 aa) fasta scores: E(): 1.6e-10, 27.18% id in 320 aa NP_789271.1 Similar to Streptomyces coelicolor ATP synthase protein I AtpI or SCO5366 or 2SC6G5.10 SWALL:ATPZ_STRCO (SWALL:P50015) (144 aa) fasta scores: E(): 5.9, 20.63% id in 126 aa NP_789272.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_789273.1 Similar to Bacillus subtilis ATP synthase C chain AtpE SWALL:ATPL_BACSU (SWALL:P37815) (70 aa) fasta scores: E(): 6.5e-07, 49.18% id in 61 aa NP_789274.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_789275.1 Similar to Streptomyces lividans ATP synthase delta chain AtpH SWALL:ATPD_STRLI (SWALL:P50008) (272 aa) fasta scores: E(): 3.2e-08, 27.27% id in 264 aa NP_789276.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_789277.1 Similar to Streptomyces lividans ATP synthase gamma chain AtpG SWALL:ATPG_STRLI (SWALL:P50007) (302 aa) fasta scores: E(): 4.5e-22, 43.07% id in 332 aa NP_789278.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_789279.1 Similar to Streptomyces lividans ATP synthase epsilon chain AtpC SWALL:ATPE_STRCO (SWALL:P50011) (123 aa) fasta scores: E(): 7.2e-05, 35.48% id in 93 aa NP_789280.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_789281.1 Similar to Streptomyces antibioticus guanosine pentaphosphate synthetase GpsI SWALL:Q53597 (EMBL:U19858) (740 aa) fasta scores: E(): 1.3e-101, 60.97% id in 738 aa, and to Yersinia enterocolitica polyribonucleotide nucleotidyltransferase Pnp SWALL:PNP_YEREN (SWALL:O34275) (706 aa) fasta scores: E(): 1.7e-59, 42.11% id in 729 aa NP_789282.1 Similar to Alcaligenes eutrophus cobalt-zinc-cadmium resistance protein CzcD SWALL:CZCD_ALCEU (SWALL:P13512) (316 aa) fasta scores: E(): 8e-25, 34.72% id in 288 aa, and to Escherichia coli zinc transporter ZitB or b0752 SWALL:ZITB_ECOLI (SWALL:P75757) (313 aa) fasta scores: E(): 1.6e-24, 31.92% id in 307 aa NP_789283.1 Similar to Clostridium acetobutylicum predicted permease cac1677 SWALL:Q97IG4 (EMBL:AE007677) (341 aa) fasta scores: E(): 4.9e-14, 25.91% id in 328 aa NP_789284.1 N-terminal region similar to that of Streptomyces reticuli AbpS protein SWALL:O07481 (EMBL:Z97071) (311 aa) fasta scores: E(): 3.2e-06, 26.68% id in 296 aa NP_789286.1 Similar to Rhodobacter sphaeroides cysteine desulfurase NifS SWALL:NIFS_RHOSH (SWALL:Q01179) (387 aa) fasta scores: E(): 6.7e-25, 31.34% id in 386 aa, and to Methanosarcina thermophila probable cysteine desulfurase IscS or NifS SWALL:ISCS_METTE (SWALL:P57795) (404 aa) fasta scores: E(): 1.2e-19, 32.29% id in 387 aa NP_789287.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_789288.1 Similar to Rhodothermus marinus DNA ligase LigA or Lig SWALL:DNLJ_RHOMR (SWALL:P49421) (712 aa) fasta scores: E(): 2.1e-36, 35.52% id in 625 aa NP_789289.1 Similar to Bacillus subtilis glutamyl-tRNA(gln) amidotransferase subunit C GatC SWALL:GATC_BACSU (SWALL:O06492) (96 aa) fasta scores: E(): 0.43, 28.86% id in 97 aa NP_789290.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_789291.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_789292.1 Weakly similar to Streptomyces coelicolor putative membrane protein SCO7017 or SC1H10.06c SWALL:Q9L038 (EMBL:AL352956) (301 aa) fasta scores: E(): 0.034, 23.64% id in 313 aa NP_789293.1 Similar to Corynebacterium glutamicum ABC-type transporter, permease components cgl1078 SWALL:BAB98471 (EMBL:AP005277) (196 aa) fasta scores: E(): 4.9e-17, 37.12% id in 167 aa NP_789294.1 Similar to Staphylococcus aureus Mw0959 protein SWALL:BAB94824 (EMBL:AP004825) (466 aa) fasta scores: E(): 1.1e-17, 29.5% id in 505 aa, and to Escherichia coli taurine transport ATP-binding protein TauB or SsiB or b0366 SWALL:TAUB_ECOLI (SWALL:Q47538) (255 aa) fasta scores: E(): 2e-10, 30.73% id in 218 aa NP_789295.1 Similar to Corynebacterium glutamicum ABC-type transporter, permease components cgl1080 SWALL:BAB98473 (EMBL:AP005277) (251 aa) fasta scores: E(): 1.9e-14, 28.8% id in 243 aa NP_789296.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO4848 or SC5G8.16 SWALL:Q9KZ98 (EMBL:AL353872) (79 aa) fasta scores: E(): 1.2, 31.74% id in 63 aa NP_789297.1 3'-5' exoribonuclease specific for small oligoribonuclotides NP_789298.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_789300.1 Similar to Streptomyces coelicolor putative single-strand DNA binding protein SCO2683 or SCC61A.04c SWALL:Q9KYI9 (EMBL:AL356595) (156 aa) fasta scores: E(): 2.4e-10, 41.07% id in 112 aa, and to Mycobacterium tuberculosis single-strand binding protein Ssb or rv0054 or mt0060 or mtcy21d4.17 SWALL:SSB_MYCTU (SWALL:P71711) (164 aa) fasta scores: E(): 1.6e-07, 30.08% id in 113 aa NP_789301.1 No significant database matches. Note possible alternative downstream start codons NP_789302.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence NP_789303.1 Similar to Streptomyces coelicolor hypothetical protein SCO2676 or SC6D10.19c SWALL:Q9L245 (EMBL:AL138538) (136 aa) fasta scores: E(): 3.1e-05, 34.64% id in 153 aa NP_789304.1 Similar to Streptomyces lividans aminopeptidase N PepN SWALL:AMPN_STRLI (SWALL:Q11010) (857 aa) fasta scores: E(): 8.4e-69, 39.86% id in 858 aa NP_789305.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2466c or mtv008.22C SWALL:O53193 (EMBL:AL021246) (207 aa) fasta scores: E(): 1e-25, 41.91% id in 198 aa NP_789306.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_789307.1 Similar to Escherichia coli endonuclease VIII Nei or b0714 SWALL:END8_ECOLI (SWALL:P50465) (262 aa) fasta scores: E(): 6.4e-06, 24.34% id in 304 aa, and to Streptomyces coelicolor putative DNA repair hydrolase SCC80.11c or SCO2626 SWALL:Q9F308 (EMBL:AL442143) (306 aa) fasta scores: E(): 7.3e-12, 31.26% id in 323 aa NP_789308.1 Similar to Streptomyces coelicolor hypothetical protein SCO5756 or SC7C7.11 SWALL:O86816 (EMBL:AL031031) (156 aa) fasta scores: E(): 3.8e-12, 37.68% id in 138 aa NP_789309.1 Similar to Corynebacterium glutamicum ribonuclease D cgl1901 SWALL:BAB99294 (EMBL:AP005280) (421 aa) fasta scores: E(): 2.8e-23, 33.97% id in 365 aa, and to Escherichia coli ribonuclease D Rnd or b1804 SWALL:RND_ECOLI (SWALL:P09155) (375 aa) fasta scores: E(): 0.003, 25.5% id in 247 aa NP_789310.1 Similar to Streptomyces coelicolor hypothetical protein SCO6030 or SC1C3.18c SWALL:O69860 (EMBL:AL023702) (238 aa) fasta scores: E(): 7.3e-15, 34.1% id in 173 aa NP_789311.1 Weakly similar to Sulfolobus tokodaii hypothetical protein St0285 SWALL:Q975Z3 (EMBL:AP000982) (213 aa) fasta scores: E(): 0.001, 29.19% id in 161 aa NP_789312.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3284 or mt3383 or mtcy71.24 SWALL:YW84_MYCTU (SWALL:P96889) (143 aa) fasta scores: E(): 7.6e-19, 45.86% id in 133 aa NP_789313.1 Similar to Mycobacterium tuberculosis putative thiosulfate sulfurtransferase SseA or Rv3283 or mt3382 or mtcy71.23 SWALL:THT2_MYCTU (SWALL:P96888) (297 aa) fasta scores: E(): 2.1e-65, 56.33% id in 284 aa, and to Saccharopolyspora erythraea putative thiosulfate sulfurtransferase CysA SWALL:THTR_SACER (SWALL:P16385) (281 aa) fasta scores: E(): 3.2e-54, 51.67% id in 269 aa NP_789314.1 Short C-terminal region similar to that of Streptomyces coelicolor hypothetical protein SCO2326 or SCC53.17 SWALL:Q9KXJ4 (EMBL:AL357591) (154 aa) fasta scores: E(): 1.6e-13, 51.54% id in 97 aa NP_789315.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO0796 or SCF43.07 SWALL:Q9RD81 (EMBL:AL136502) (419 aa) fasta scores: E(): 6.6e-08, 22% id in 359 aa NP_789316.1 C-terminal region similar to Corynebacterium glutamicum hypothetical protein Cgl2257 SWALL:BAB99650 (EMBL:AP005281) (344 aa) fasta scores: E(): 5.7e-32, 38.72% id in 315 aa. N-terminal region similar to Escherichia coli DedA protein or b2317 or z3579 or ecs3201 SWALL:DEDA_ECOLI (SWALL:P09548) (219 aa) fasta scores: E(): 1.4e-09, 28.65% id in 178 aa NP_789317.1 Similar to Sulfolobus solfataricus anthranilate synthase component I TrpE or Sso0893 SWALL:TRPE_SULSO (SWALL:Q06128) (421 aa) fasta scores: E(): 5.8e-35, 42.96% id in 263 aa, and to Streptomyces coelicolor anthranilate synthase component I TrpE or SCO3214 or SCE8.07c SWALL:TRPE_STRCO (SWALL:Q9Z4W7) (511 aa) fasta scores: E(): 5.1e-33, 32.27% id in 474 aa NP_789318.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_789319.1 Similar to Thermoanaerobacter tengcongensis DNA uptake protein and related DNA-binding proteins ComEA or tte0926 SWALL:Q8RB96 (EMBL:AE013058) (196 aa) fasta scores: E(): 8.4e-06, 42.64% id in 136 aa, and to Bacillus subtilis ComE operon protein 1 ComEA or ComE1 SWALL:CME1_BACSU (SWALL:P39694) (205 aa) fasta scores: E(): 0.00054, 33.5% id in 197 aa NP_789320.1 Similar to N-terminal portion of Bacillus subtilis ComE operon protein 3 ComEC or ComE3 SWALL:CME3_BACSU (SWALL:P39695) (776 aa) fasta scores: E(): 4.4e-06, 24.23% id in 487 aa NP_789321.1 Similar to C-terminal portion of Bacillus subtilis comE operon protein 3 ComEC or ComE3 SWALL:CME3_BACSU (SWALL:P39695) (776 aa) fasta scores: E(): 2e-10, 24.83% id in 298 aa NP_789322.1 Weakly similar to Corynebacterium glutamicum predicted DNA polymerase III delta subunit cgl2346 SWALL:BAB99739 (EMBL:AP005281) (325 aa) fasta scores: E(): 4.6e-15, 25.23% id in 325 aa NP_789325.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_789326.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_789327.1 Similar to Streptomyces coelicolor hypothetical protein SCO1500 or SC9C5.24c SWALL:Q9KXQ0 (EMBL:AL357523) (167 aa) fasta scores: E(): 1.3e-08, 38.06% id in 134 aa NP_789328.1 Similar to Neisseria meningitidis hypothetical protein Nmb0669 SWALL:Q9K0E0 (EMBL:AE002421) (331 aa) fasta scores: E(): 7e-21, 30.97% id in 339 aa NP_789329.1 Similar to Neisseria polysaccharea shikimate 5-dehydrogenase AroE SWALL:AROE_NEIPO (SWALL:P95399) (269 aa) fasta scores: E(): 0.0029, 36.73% id in 98 aa, and to Xylella fastidiosa shikimate 5-dehydrogenase xf0624 SWALL:Q9PFN3 (EMBL:AE003908) (282 aa) fasta scores: E(): 2e-05, 34.14% id in 123 aa NP_789330.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_789331.1 Similar to Lactococcus lactis shikimate kinase AroK SWALL:AROK_LACLC (SWALL:P43906) (162 aa) fasta scores: E(): 2.1e-08, 30.81% id in 159 aa NP_789332.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_789333.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_789334.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_789335.1 Similar to Bacillus caldolyticus dihydroorotase PyrC SWALL:PYRC_BACCL (SWALL:P46538) (427 aa) fasta scores: E(): 1.7e-44, 37.46% id in 387 aa NP_789336.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_789337.1 Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 9.4e-176, 49.22% id in 1099 aa NP_789338.1 Similar to Mycobacterium smegmatis orotidine 5'-phosphate decarboxylase PyrF SWALL:PYRF_MYCSM (SWALL:O08323) (276 aa) fasta scores: E(): 4.1e-22, 38.79% id in 281 aa, and to Myxococcus xanthus orotidine 5'-phosphate decarboxylase PyrF or UraA SWALL:PYRF_MYXXA (SWALL:P24220) (288 aa) fasta scores: E(): 3.4e-16, 30.43% id in 276 aa NP_789339.1 Similar to Escherichia coli guanylate kinase Gmk or SpoR or b3648 SWALL:KGUA_ECOLI (SWALL:P24234) (207 aa) fasta scores: E(): 4.2e-19, 39.42% id in 175 aa, and to Streptomyces coelicolor guanylate kinase Gmk or SCO1479 or SC9C5.03c SWALL:KGUA_STRCO (SWALL:Q9KXS0) (197 aa) fasta scores: E(): 2e-31, 50.55% id in 180 aa. Note possible alternative upstream translational start sites. NP_789340.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_789341.1 Similar to many predicted flavoproteins eg. Mycobacterium tuberculosis DNA/pantothenate metabolism flavoprotein homolog Dfp or rv1391 or mt1436 or mtcy21b4.08 SWALL:DFP_MYCTU (SWALL:P71661) (418 aa) fasta scores: E(): 7.4e-51, 42.05% id in 409 aa NP_789342.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_789343.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_789344.1 Similar to Escherichia coli methionyl-tRNA formyltransferase Fmt or b3288 SWALL:FMT_ECOLI (SWALL:P23882) (314 aa) fasta scores: E(): 1.9e-19, 32.57% id in 307 aa, and to Streptomyces coelicolor methionyl-trna formyltransferase fmt or sco1473 or scl6.30C SWALL:Q9L0Y6 (EMBL:AL159139) (310 aa) fasta scores: E(): 4e-26, 34.81% id in 316 aa NP_789345.1 Similar to Streptomyces coelicolor ribulose-phosphate 3-epimerase Rpe or SCO1464 or SCl6.21c SWALL:RPE_STRCO (SWALL:Q9L0Z5) (228 aa) fasta scores: E(): 3.3e-32, 44.97% id in 209 aa, and to Oryza sativa D-ribulose-5-phosphate 3-epimerase SWALL:Q9SE42 (EMBL:AF189365) (228 aa) fasta scores: E(): 8.5e-23, 36.57% id in 216 aa NP_789346.1 Similar to Escherichia coli mannose-1-phosphate guanylyltransferase ManC or RfbM SWALL:RFM7_ECOLI (SWALL:P37741) (464 aa) fasta scores: E(): 2.1e-32, 33.51% id in 367 aa, and to Deinococcus radiodurans mannose-1-phosphate guanylyltransferase dra0032 SWALL:Q9RZC2 (EMBL:AE001862) (372 aa) fasta scores: E(): 2.4e-38, 35.09% id in 359 aa NP_789347.1 Similar to Mycobacterium tuberculosis phosphate-binding protein 2 precursor PstS2 or rv0932c or mt0959 or mtcy08d9.07 SWALL:PST2_MYCTU (SWALL:O05870) (370 aa) fasta scores: E(): 2.1e-28, 32.94% id in 340 aa NP_789348.1 Similar to Mycobacterium tuberculosis phosphate transport system permease protein PstC-2 or Rv0929 or mt0956 or mtcy21c12.23 SWALL:PSC2_MYCTU (SWALL:O86344) (324 aa) fasta scores: E(): 2.8e-30, 40.83% id in 289 aa, and to Escherichia coli phosphate transport system permease protein PstC or PhoW or b3727 or z5218 or ecs4663 SWALL:PSTC_ECOLI (SWALL:P07653) (319 aa) fasta scores: E(): 6.4e-25, 34.01% id in 294 aa NP_789349.1 Similar to Mycobacterium tuberculosis phosphate transport system permease protein PstA-1 or Rv0930 or mt0957 or mtcy21c12.24 SWALL:PSA1_MYCTU (SWALL:O86345) (305 aa) fasta scores: E(): 6.3e-39, 43.35% id in 286 aa, and to Escherichia coli phosphate transport system permease protein PstA or PhoT or b3726 SWALL:PSTA_ECOLI (SWALL:P07654) (296 aa) fasta scores: E(): 1.7e-29, 37.5% id in 280 aa NP_789350.1 Similar to Mycobacterium smegmatis putative ABC transporter nucleotide binding subunit Mtp1 SWALL:O68469 (EMBL:AF045938) (258 aa) fasta scores: E(): 4.9e-48, 57.52% id in 259 aa, and to Bacillus subtilis hypothetical ABC transporter ATP-binding protein YqgJ yqgJ SWALL:YQGJ_BACSU (SWALL:P46341) (269 aa) fasta scores: E(): 7.5e-40, 50.78% id in 256 aa NP_789351.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_789352.1 Doubtful CDS. No significant database matches NP_789353.1 Similar to Streptomyces coelicolor putative transcriptional factor regulator SCO4232 or SCD8A.05 SWALL:Q9L0Q9 (EMBL:AL160331) (160 aa) fasta scores: E(): 4.3e-32, 66.03% id in 159 aa, and to Myxococcus xanthus CarD protein SWALL:Q50887 (EMBL:Z56280) (316 aa) fasta scores: E(): 1.1e-09, 28.48% id in 158 aa NP_789354.1 Fusion protein. N-terminal region similar to Streptomyces coelicolor 2-c-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD or SCO4233 or SCD8A.06 SWALL:ISPD_STRCO (SWALL:Q9L0Q8) (270 aa) fasta scores: E(): 1.5e-12, 36.05% id in 233 aa Full length similarity to Rhizobium meliloti IspD/IspF bifunctional enzyme [includes: 2-c-methyl-D-erythritol 4- phosphate cytidylyltransferase ispdf or r01456 or smc01040 SWALL:ISDF_RHIME (SWALL:Q92Q90) (434 aa) fasta scores: E(): 5.7e-11, 28.7% id in 425 aa. C-terminal region similar to Escherichia coli 2-c-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF or MecS or b2746 or z4054 or ecs3600 SWALL:ISPF_ECOLI (SWALL:P36663) (159 aa) fasta scores: E(): 3.9e-10, 35.52% id in 152 aa NP_789355.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_789356.1 Similar to Mycobacterium leprae putative methyltransferase Ml0324 SWALL:Q9CCW4 (EMBL:AL583918) (278 aa) fasta scores: E(): 2.3e-30, 41.29% id in 247 aa, and to Bacillus subtilis hypothetical tRNA/rRNA methyltransferase YacO SWALL:YACO_BACSU (SWALL:Q06753) (249 aa) fasta scores: E(): 2.1e-23, 33.19% id in 244 aa NP_789357.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2969c or mt3047 or mtcy349.18 SWALL:O33272 (EMBL:Z83018) (261 aa) fasta scores: E(): 8.8e-05, 29.31% id in 249 aa NP_789359.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_789360.1 Similar to Synechocystis sp. glucose-6-phosphate isomerase pgi or slr1349 SWALL:G6PI_SYNY3 (SWALL:P52983) (531 aa) fasta scores: E(): 4.8e-07, 26.91% id in 353 aa NP_789361.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate NP_789362.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_789363.1 converts protoheme IX and farnesyl diphosphate to heme O NP_789364.1 Similar to Bacillus stearothermophilus heme O oxygenase CtaA SWALL:P94346 (EMBL:D70843) (320 aa) fasta scores: E(): 0.00037, 26.71% id in 146 aa, and to Bacillus subtilis cytochrome aa3 controlling protein CtaA SWALL:CTAA_BACSU (SWALL:P12946) (306 aa) fasta scores: E(): 0.031, 20.94% id in 296 aa NP_789365.1 Similar to Streptomyces coelicolor hypothetical protein SCO1925 or scc22.07C SWALL:Q9XAD1 (EMBL:AL096839) (473 aa) fasta scores: E(): 3.4e-141, 74.13% id in 464 aa, and to Escherichia coli SufB protein or b1683 SWALL:SUFB_ECOLI (SWALL:P77522) (495 aa) fasta scores: E(): 3.1e-61, 38.7% id in 478 aa NP_789366.1 Similar to Streptomyces coelicolor hypothetical protein SCO1924 or SCC22.06c SWALL:Q9XAD2 (EMBL:AL096839) (394 aa) fasta scores: E(): 1.5e-45, 37.46% id in 379 aa NP_789367.1 Similar to Escherichia coli 3-phenylpropionate dioxygenase ferredoxin subunit HcaC or PhdB or HcaA3 or b2540 or z3811 or ecs3406 SWALL:HCAC_ECOLI (SWALL:P77266) (106 aa) fasta scores: E(): 3.4e-14, 45.91% id in 98 aa, and to Pseudomonas putida benzene 1,2-dioxygenase system ferredoxin component BedB SWALL:BEDB_PSEPU (SWALL:Q07947) (107 aa) fasta scores: E(): 7.7e-11, 39.78% id in 93 aa NP_789368.1 Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCO1922 or SCC22.04c SWALL:Q9XAD4 (EMBL:AL096839) (254 aa) fasta scores: E(): 2.5e-55, 70.04% id in 247 aa, and to Cyanidium caldarium probable ATP-dependent transporter Ycf16 or Ycf33 SWALL:ABCX_CYACA (SWALL:Q9TLX1) (254 aa) fasta scores: E(): 8e-32, 48.19% id in 249 aa NP_789369.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1466 or mtv007.13 or mt1513 SWALL:O53157 (EMBL:AL021184) (115 aa) fasta scores: E(): 3.6e-18, 52.52% id in 99 aa NP_789370.1 Weakly similar to Streptomyces coelicolor putative membrane protein SCO1829 or SCI8.14 SWALL:Q9RJ39 (EMBL:AL132644) (290 aa) fasta scores: E(): 5.4e-10, 27.75% id in 263 aa NP_789371.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_789372.1 Similar to Bacillus stearothermophilus L-arabinose transport ATP-binding protein AraG SWALL:ARAG_BACST (SWALL:Q9S472) (513 aa) fasta scores: E(): 5e-88, 55.07% id in 512 aa, and to Escherichia coli D-allose transport ATP-binding protein AlsA or b4087 SWALL:ALSA_ECOLI (SWALL:P32721) (510 aa) fasta scores: E(): 3.8e-48, 36.54% id in 509 aa NP_789373.1 Similar to Bacillus stearothermophilus L-arabinose membrane permease AraH SWALL:Q9S471 (EMBL:AF160811) (407 aa) fasta scores: E(): 3.6e-55, 42.32% id in 378 aa, and to Bacillus subtilis ribose transport system permease protein RbsC SWALL:RBSC_BACSU (SWALL:P36948) (322 aa) fasta scores: E(): 2.6e-15, 29.34% id in 368 aa NP_789374.1 Similar to Agrobacterium tumefaciens multiple sugar-binding periplasmic receptor ChvE precursor or atu2348 or agr_c_4267 SWALL:CHVE_AGRT5 (SWALL:P25548) (354 aa) fasta scores: E(): 4.6e-43, 42.68% id in 328 aa, and to Escherichia coli D-xylose-binding periplasmic protein precursor XylF or XylT or b3566 SWALL:XYLF_ECOLI (SWALL:P37387) (330 aa) fasta scores: E(): 1.8e-10, 34.19% id in 310 aa NP_789375.1 Similar to Streptomyces clavuligerus Pbp2 protein or PbpA SWALL:O54201 (EMBL:AJ001743) (696 aa) fasta scores: E(): 7.8e-10, 32.36% id in 207 aa, and to Bacillus subtilis penicillin-binding protein DacF precursor SWALL:DACF_BACSU (SWALL:P38422) (389 aa) fasta scores: E(): 0.0009, 23.07% id in 299 aa NP_789376.1 Similar to Alcaligenes eutrophus alcohol dehydrogenase Adh SWALL:ADH_ALCEU (SWALL:P14940) (366 aa) fasta scores: E(): 3.4e-24, 35.13% id in 370 aa NP_789377.1 Similar to Escherichia coli putative deoxyribonuclease YcfH or b1100 or z1739 or ecs1478 SWALL:YCFH_ECOLI (SWALL:P37346) (265 aa) fasta scores: E(): 5.3e-15, 30.38% id in 283 aa NP_789378.1 No significant database matches. Frameshifted at potentially variable G(11) tract after aa 14. Contain 6x PTT(S/V) repeat at residue 153-176. NP_789379.1 Similar to Streptomyces coelicolor hypothetical protein SCO2947 or SCE59.06c SWALL:Q9L1U7 (EMBL:AL138851) (97 aa) fasta scores: E(): 2.5e-08, 48.27% id in 58 aa NP_789380.1 Similar to Ralstonia solanacearum probable dehydrogenase oxidoreductase protein Rsp0305 or rs05466 SWALL:Q8XT12 (EMBL:AL646077) (255 aa) fasta scores: E(): 1.2e-07, 32.06% id in 237 aa, and to Escherichia coli 7-alpha-hydroxysteroid dehydrogenase HdhA or HsdA or b1619 or z2624 or ecs2327 SWALL:HDHA_ECOLI (SWALL:P25529) (255 aa) fasta scores: E(): 2.4e-05, 28.63% id in 234 aa NP_789381.1 Similar to Pseudomonas stutzeri TatC protein SWALL:Q9AKS0 (EMBL:AJ299712) (267 aa) fasta scores: E(): 8.5e-12, 31.12% id in 241 aa, and to Streptomyces lividans twin arginine translocation pathway TatC SWALL:Q9F2H3 (EMBL:AJ251149) (301 aa) fasta scores: E(): 5.9e-19, 35.1% id in 245 aa NP_789382.1 Similar to Escherichia coli sec-independent protein translocase protein TatA or MttA1 or b3836 or z5358 or ecs4766 SWALL:TATA_ECOLI (SWALL:O65938) (89 aa) fasta scores: E(): 0.11, 28.57% id in 91 aa, and to Helicobacter pylori sec-independent protein translocase protein TatA/E homolog TatA or hp0320 SWALL:TATA_HELPY (SWALL:O25088) (79 aa) fasta scores: E(): 0.00039, 31.25% id in 80 aa NP_789383.1 Similar to Streptomyces chrysomallus FKBP-33 precursor FkbB SWALL:Q53919 (EMBL:Z34523) (312 aa) fasta scores: E(): 1.8e-12, 36.29% id in 281 aa NP_789384.1 Similar to Streptomyces coelicolor hypothetical protein SCO1651 or SCI41.34c SWALL:Q9RJ57 (EMBL:AL132648) (300 aa) fasta scores: E(): 7.6e-17, 35.97% id in 303 aa NP_789385.1 Similar to Mycobacterium leprae hypothetical protein Ml1306 SWALL:Q9CC38 (EMBL:AL583921) (274 aa) fasta scores: E(): 1.7e-30, 36.36% id in 275 aa NP_789386.1 Similar to Escherichia coli cysteinyl-tRNA synthetase CysS or b0526 SWALL:SYC_ECOLI (SWALL:P21888) (461 aa) fasta scores: E(): 2e-23, 32.06% id in 315 aa, and to Streptomyces coelicolor putative cysteinyl-trna synthetase sco1663 or sci52.05C SWALL:Q9ADA4 (EMBL:AL590507) (409 aa) fasta scores: E(): 6e-44, 40.22% id in 348 aa NP_789387.1 Similar to Staphylococcus aureus putative undecaprenol kinase Upk or BacA or mw0645 SWALL:BAB94510 (EMBL:AP004824) (291 aa) fasta scores: E(): 6.4e-18, 27.93% id in 290 aa, and to Streptomyces coelicolor putative undecaprenol kinase 2 Upk2 or BacA2 or SCO1326 or 2SCG61.08 SWALL:UPK2_STRCO (SWALL:Q9K407) (291 aa) fasta scores: E(): 1.4e-25, 32.98% id in 285 aa NP_789388.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_789389.1 Similar to Escherichia coli 3-oxoacyl-[acyl-carrier protein] reductase FabG or b1093 SWALL:FABG_ECOLI (SWALL:P25716) (244 aa) fasta scores: E(): 1.5e-33, 43.51% id in 239 aa, and to Streptomyces coelicolor probable 3-oxacyl- FabG or SCO1815 or SCI28.09c SWALL:Q9S274 (EMBL:AL096844) (234 aa) fasta scores: E(): 1.3e-42, 51.93% id in 233 aa NP_789390.1 Similar to Methanosarcina mazei glycosyltransferase mm1142 SWALL:AAM30838 (EMBL:AE013343) (379 aa) fasta scores: E(): 3.6e-24, 29.59% id in 392 aa, and to Arabidopsis thaliana sulfolipid synthase Sqd2 SWALL:Q8S4F6 (EMBL:AF454354) (510 aa) fasta scores: E(): 2.8e-11, 27.91% id in 283 aa NP_789391.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO0973 or SCM11.28 SWALL:Q9RIT4 (EMBL:AL133278) (419 aa) fasta scores: E(): 2.9e-09, 28.63% id in 234 aa NP_789392.1 Similar to Thermus thermophilus peptide Deformylase Def SWALL:DEF_THETH (SWALL:P43522) (192 aa) fasta scores: E(): 6.4e-15, 38.69% id in 168 aa, and to Mycobacterium leprae peptide deformylase Def or ml1929 SWALL:DEF_MYCLE (SWALL:Q9CBI2) (197 aa) fasta scores: E(): 8.2e-20, 39.6% id in 202 aa NP_789393.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_789394.1 Similar to Mycobacterium tuberculosis 6-phosphogluconolactonase Pgl or DevB or Rv1445c or mt1492 or mtcy493.09 SWALL:6PGL_MYCTU (SWALL:O06814) (247 aa) fasta scores: E(): 8.5e-26, 34.41% id in 247 aa, and to Actinobacillus actinomycetemcomitans 6-phosphogluconolactonase Pgl or DevB SWALL:6PGL_ACTAC (SWALL:P70715) (232 aa) fasta scores: E(): 6.4e-17, 31.93% id in 238 aa NP_789395.1 Similar to Bacillus stearothermophilus inorganic pyrophosphatase Ppa or pmk2ppA SWALL:IPYR_BACST (SWALL:O05724) (164 aa) fasta scores: E(): 5.1e-27, 44.3% id in 158 aa NP_789397.1 Similar to Streptomyces coelicolor putative electron transport protein SCO1943 or SCC54.03c SWALL:Q9Z522 (EMBL:AL035591) (111 aa) fasta scores: E(): 3.2e-11, 44.34% id in 106 aa NP_789398.1 Similar to Streptomyces coelicolor protein-export membrane protein SecG or SCO1944 or SCC54.04c SWALL:SECG_STRCO (SWALL:Q9Z521) (102 aa) fasta scores: E(): 7.6e-10, 50.66% id in 75 aa, and to Escherichia coli protein-export membrane protein SecG or b3175 or z4537 or ecs4054 SWALL:SECG_ECOLI (SWALL:P33582) (110 aa) fasta scores: E(): 0.22, 32.83% id in 67 aa NP_789399.1 Similar to Corynebacterium glutamicum triosephosphate isomerase TpiA or Tpi or cgl1586 SWALL:TPIS_CORGL (SWALL:P19583) (259 aa) fasta scores: E(): 1e-15, 35% id in 280 aa NP_789400.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_789401.1 Similar to Corynebacterium glutamicum glyceraldehyde 3-phosphate dehydrogenase Gap or cgl1588 SWALL:G3P_CORGL (SWALL:Q01651) (336 aa) fasta scores: E(): 2.2e-80, 59.58% id in 339 aa NP_789402.1 Similar to Propionibacterium freudenreichii shermanii superoxide dismutase [mn/fe] sodA SWALL:SODM_PROFR (SWALL:P80293) (201 aa) fasta scores: E(): 9.6e-47, 61.53% id in 195 aa NP_789403.1 Similar to Streptomyces coelicolor WhiA SWALL:Q9S4Y1 (EMBL:AF106003) (330 aa) fasta scores: E(): 5e-40, 42.71% id in 309 aa NP_789404.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_789405.1 Similar to Escherichia coli excinuclease ABC subunit A UvrA or DinE or b4058 SWALL:UVRA_ECOLI (SWALL:P07671) (940 aa) fasta scores: E(): 2e-109, 48.39% id in 965 aa NP_789406.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_789407.1 Similar to Bacillus subtilis dephospho-CoA kinase CoaE SWALL:COAE_BACSU (SWALL:O34932) (197 aa) fasta scores: E(): 1.3e-06, 30.15% id in 199 aa NP_789408.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_789409.1 Similar to Mycobacterium tuberculosis DNA polymerase I PolA or Rv1629 or mt1665 or mtcy01b2.21 SWALL:DPO1_MYCTU (SWALL:Q07700) (904 aa) fasta scores: E(): 1.4e-36, 42.91% id in 268 aa NP_789410.1 Similar to Streptomyces coelicolor putative response regulator SCO2013 or SC7H2.27c SWALL:Q9S2J0 (EMBL:AL109732) (218 aa) fasta scores: E(): 3.7e-35, 53.51% id in 185 aa, and to Streptomyces coelicolor AbsA2 or SCO3226 or SCE8.19 SWALL:Q53894 (EMBL:U51332) (222 aa) fasta scores: E(): 7.4e-11, 43.47% id in 115 aa, and to Bacillus subtilis chemotaxis protein CheY homolog or CheB SWALL:CHEY_BACSU (SWALL:P24072) (119 aa) fasta scores: E(): 1.2e-10, 38.59% id in 114 aa NP_789411.1 Similar to Corynebacterium glutamicum pyruvate kinase Pyk or cgl2089 SWALL:KPYK_CORGL (SWALL:Q46078) (475 aa) fasta scores: E(): 1.1e-83, 50.63% id in 470 aa NP_789412.1 C-terminal region similar to those from proteins of undefined function eg. Clostridium acetobutylicum starch degrading enzyme precursor SWALL:Q45834 (EMBL:X70334) (503 aa) fasta scores: E(): 2.7e-11, 38.51% id in 148 aa NP_789413.1 synthesizes RNA primers at the replication forks NP_789414.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate NP_789415.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_789416.2 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_789417.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_789418.1 Similar to Mycobacterium leprae hypothetical protein Ml0628 or b1937_f1_21 SWALL:YN67_MYCLE (SWALL:Q49752) (178 aa) fasta scores: E(): 3.3e-15, 35.61% id in 146 aa NP_789419.1 Similar to Synechocystis sp. hypothetical hit-like protein Slr1234 SWALL:YHIT_SYNY3 (SWALL:P73481) (114 aa) fasta scores: E(): 6.7e-15, 43.13% id in 102 aa NP_789420.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_789421.1 Similar to Escherichia coli chaperone protein DnaJ or GroP or b0015 SWALL:DNAJ_ECOLI (SWALL:P08622) (375 aa) fasta scores: E(): 1.7e-31, 34.85% id in 373 aa NP_789423.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_789424.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_789425.1 Similar to Corynebacterium glutamicum GTP pyrophosphokinase RelA or cgl1653 SWALL:RELA_CORGL (SWALL:O87331) (760 aa) fasta scores: E(): 2e-124, 43.98% id in 732 aa, and to Escherichia coli GTP pyrophosphokinase RelA or b2784 or z4099 or ecs3644 SWALL:RELA_ECOLI (SWALL:P11585) (744 aa) fasta scores: E(): 3.3e-79, 34.23% id in 739 aa NP_789427.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_789428.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_789429.1 Similar to Streptomyces coelicolor putative secreted protein SCO1517 or SCL2.07c SWALL:Q9L292 (EMBL:AL137778) (169 aa) fasta scores: E(): 0.038, 25.74% id in 167 aa NP_789430.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_789431.1 Similar to Thermus thermophilus holliday junction DNA helicase RuvA SWALL:RUVA_THETH (SWALL:Q9F1Q3) (191 aa) fasta scores: E(): 1e-15, 38.23% id in 170 aa NP_789432.1 Similar to Escherichia coli crossover junction endodeoxyribonuclease RuvC or b1863 or z2915 or ecs2573 SWALL:RUVC_ECOLI (SWALL:P24239) (172 aa) fasta scores: E(): 2e-07, 27.38% id in 168 aa, and to Mycobacterium leprae crossover junction endodeoxyribonuclease RuvC or ml0481 or b1177_c3_226 SWALL:RUVC_MYCLE (SWALL:P40834) (188 aa) fasta scores: E(): 1.6e-20, 40% id in 185 aa NP_789433.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2603c or mt2678 or mtci270a.02 SWALL:YQ03_MYCTU (SWALL:O33214) (251 aa) fasta scores: E(): 5.5e-43, 52.01% id in 248 aa NP_789434.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate NP_789435.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_789436.1 Similar to Streptomyces coelicolor hypothetical HIT family protein SCL2.20c or SCO1530 SWALL:Q9L279 (EMBL:AL137778) (186 aa) fasta scores: E(): 7.6e-35, 50% id in 168 aa NP_789437.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_789438.1 Similar to Escherichia coli glutamine synthetase GlnA or b3870 or z5406 or ecs4792 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 2.2e-89, 48.62% id in 471 aa NP_789439.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_789440.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_789441.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2229c or mt2288 or mtcy427.10C SWALL:YM29_MYCTU (SWALL:Q10513) (245 aa) fasta scores: E(): 5.6e-06, 24.78% id in 234 aa NP_789442.1 Similar to Streptomyces coelicolor hypothetical protein SCO2301 or SCC30.09c SWALL:YN01_STRCO (SWALL:Q9L012) (285 aa) fasta scores: E(): 4.7e-28, 36.74% id in 283 aa NP_789443.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2238c or mt2298 or mtcy427.19C SWALL:YM38_MYCTU (SWALL:Q10520) (153 aa) fasta scores: E(): 4.5e-19, 43.33% id in 150 aa NP_789444.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC NP_789445.1 Similar to Streptomyces coelicolor malonyl CoA:acyl carrier protein malonyltransferase FabD or SCO2387 or SC4A7.15 SWALL:P72391 (EMBL:X86475) (316 aa) fasta scores: E(): 3.4e-29, 43.08% id in 318 aa NP_789446.2 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_789447.1 carries the fatty acid chain in fatty acid biosynthesis NP_789448.1 Similar to Synechocystis sp. 3-oxoacyl-[acyl-carrier-protein] synthase II FabF or sll1069 SWALL:FABF_SYNY3 (SWALL:P73283) (416 aa) fasta scores: E(): 9.8e-58, 42.05% id in 409 aa NP_789449.1 Similar to Streptomyces coelicolor hypothetical protein SCO2391 or SC4A7.19c SWALL:Q9RDP6 (EMBL:AL133423) (164 aa) fasta scores: E(): 4e-22, 41.33% id in 150 aa NP_789450.1 Similar to Streptomyces coelicolor ubiquinol-cytochrome C reductase cytochrome B subunit QcrB or SCO2148 or SC6G10.21c SWALL:QCRB_STRCO (SWALL:Q9X806) (545 aa) fasta scores: E(): 1.2e-113, 54.15% id in 517 aa, and to Corynebacterium glutamicum cytochrome B subunit CytB or QcrB SWALL:Q9F481 (EMBL:AB047851) (539 aa) fasta scores: E(): 2.1e-92, 50.33% id in 455 aa NP_789451.1 Similar to Streptomyces coelicolor ubiquinol-cytochrome C reductase iron-sulfur subunit QcrA or SCO2149 or SC6G10.22c SWALL:QCRA_STRCO (SWALL:Q9X807) (353 aa) fasta scores: E(): 2.2e-55, 45.84% id in 325 aa, and to Corynebacterium glutamicum rieske iron-sulfur protein QcrA or cgl2190 SWALL:BAB99583 (EMBL:AJ306418) (408 aa) fasta scores: E(): 1.6e-21, 31.75% id in 381 aa NP_789452.1 Similar to Streptomyces coelicolor cytochrome C heme-binding subunit QcrC or SCO2150 or SC6G10.23c SWALL:Q9X808 (EMBL:AL049497) (269 aa) fasta scores: E(): 6.1e-43, 49.03% id in 259 aa, and to Corynebacterium glutamicum cytochrome cc1 subunit qcrC SWALL:Q9F483 (EMBL:AB047851) (283 aa) fasta scores: E(): 2e-20, 43.79% id in 274 aa NP_789453.1 Similar to Corynebacterium glutamicum cytochrome c oxidase subunit III CtaE or cgl2192 SWALL:Q9AEL8 (EMBL:AJ306418) (205 aa) fasta scores: E(): 7.2e-24, 47.93% id in 194 aa NP_789454.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO2154 or SC6G10.27c SWALL:Q9X812 (EMBL:AL049497) (132 aa) fasta scores: E(): 2.7e-10, 33.07% id in 130 aa NP_789455.1 Similar to Corynebacterium glutamicum cytochrome c oxidase subunit I CtaD SWALL:Q93HZ5 (EMBL:AB052748) (584 aa) fasta scores: E(): 2.6e-138, 63.18% id in 527 aa NP_789456.1 Similar to Paracoccus denitrificans cytochrome c oxidase polypeptide II precursor CtaC or CtaB or CoiI SWALL:COX2_PARDE (SWALL:P08306) (298 aa) fasta scores: E(): 1.3e-17, 26.49% id in 268 aa NP_789457.1 Similar to Streptomyces coelicolor hypothetical protein SCO2161 or SC6G10.34c SWALL:Q9X819 (EMBL:AL049497) (118 aa) fasta scores: E(): 6.3e-29, 70.27% id in 111 aa NP_789458.1 Similar to Streptomyces coelicolor putative peptidase SCO1074 or SCG22.20 SWALL:Q9K425 (EMBL:AL359779) (451 aa) fasta scores: E(): 4.9e-47, 37.09% id in 434 aa NP_789459.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO2169 or SC5F7.32 SWALL:Q9S2R7 (EMBL:AL096872) (251 aa) fasta scores: E(): 5e-15, 36.14% id in 166 aa NP_789460.1 catalyzes the endonucleolytic cleavage to 5'-phosphomonomer NP_789461.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors NP_789462.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv2718c or mt2791 or mtcy05a6.39C SWALL:YR18_MYCTU (SWALL:O07217) (154 aa) fasta scores: E(): 7.5e-31, 56.55% id in 145 aa NP_789463.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1830 or mt1879 or mtcy1a11.13C SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 3.4e-28, 60.28% id in 141 aa NP_789464.1 Similar to Streptomyces coelicolor hypothetical protein SCO1383 or SC1A8a.03c SWALL:Q9KZP9 (EMBL:AL353861) (246 aa) fasta scores: E(): 2.9e-11, 35.02% id in 197 aa NP_789465.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1827 or mt1875 or mtcy1a11.16C SWALL:YI27_MYCTU (SWALL:Q50606) (162 aa) fasta scores: E(): 1.2e-22, 64.35% id in 101 aa NP_789467.1 Doubtful CDS. No significant database matches NP_789468.1 Similar to Streptomyces coelicolor cell division protein FtsQ or SCO2083 or SC4A10.16c SWALL:FTSQ_STRCO (SWALL:P45518) (264 aa) fasta scores: E(): 0.011, 26.33% id in 243 aa, and to Corynebacterium glutamicum cell division protein ftsq homolog ftsq or divb or cgl2156 SWALL:FTSQ_CORGL (SWALL:P94336) (222 aa) fasta scores: E(): 9.8e-11, 26.26% id in 217 aa NP_789469.1 Similar to Streptomyces coelicolor UDP-N-acetylmuramate--alanine ligase MurC or SCO6060 or SC9B1.07 SWALL:MURC_STRCO (SWALL:Q9X827) (462 aa) fasta scores: E(): 1.1e-48, 35.83% id in 466 aa, and to Escherichia coli UDP-N-acetylmuramate--alanine ligase MurC or b0091 SWALL:MURC_ECOLI (SWALL:P17952) (491 aa) fasta scores: E(): 4.7e-41, 31.78% id in 475 aa NP_789470.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_789471.1 Similar to Streptomyces coelicolor cell division protein FtsW or SCO2085 or SC4A10.18c SWALL:Q9ZBA6 (EMBL:U10879) (456 aa) fasta scores: E(): 2.7e-36, 35.22% id in 369 aa, and to Escherichia coli cell division protein FtsW or b0089 or z0099 or ecs0093 SWALL:FTSW_ECOLI (SWALL:P16457) (414 aa) fasta scores: E(): 5e-27, 30.79% id in 354 aa NP_789472.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_789473.1 Similar to Streptomyces coelicolor UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase MurE or SCO2089 or SC4A10.22c SWALL:MURE_STRCO (SWALL:Q9S2W7) (506 aa) fasta scores: E(): 2.7e-44, 33.52% id in 528 aa, and to Escherichia coli UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase MurE or b0085 SWALL:MURE_ECOLI (SWALL:P22188) (494 aa) fasta scores: E(): 2.9e-29, 29.76% id in 467 aa NP_789474.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_789475.1 Similar to Streptomyces toyocaensis probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D-alanyl-D-alanyl ligase MurF or MurX SWALL:MURF_STRTO (SWALL:O33804) (443 aa) fasta scores: E(): 2.5e-30, 31.44% id in 442 aa, and to Escherichia coli UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D-alanyl-D-alanyl ligase MurF or Mra or b0086 SWALL:MURF_ECOLI (SWALL:P11880) (452 aa) fasta scores: E(): 3.3e-28, 31.41% id in 382 aa NP_789476.1 Similar to Bacillus subtilis penicillin-binding protein 2b PbpB SWALL:PBPB_BACSU (SWALL:Q07868) (716 aa) fasta scores: E(): 2.4e-32, 27.68% id in 596 aa, and to Streptomyces coelicolor FtsI SWALL:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 8.1e-44, 30.62% id in 604 aa NP_789477.1 Similar to Streptomyces coelicolor putative membrane protein SCO2091 or SC4A10.24c SWALL:Q9S2W5 (EMBL:AL109663) (206 aa) fasta scores: E(): 0.0016, 34.44% id in 90 aa NP_789478.1 Similar to Streptococcus pneumoniae S-adenosyl-methyltransferase MraW or sp0334 SWALL:MRAW_STRPN (SWALL:Q97SK1) (316 aa) fasta scores: E(): 2.9e-39, 40.06% id in 312 aa, and to Escherichia coli S-adenosyl-methyltransferase MraW or b0082 or z0092 or ecs0086 SWALL:MRAW_ECOLI (SWALL:P18595) (313 aa) fasta scores: E(): 4e-34, 39.68% id in 315 aa NP_789479.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_789482.1 Similar to Brevibacterium linens ggpp synthase CrtE SWALL:Q9KK76 (EMBL:AF139916) (385 aa) fasta scores: E(): 2.2e-08, 28.82% id in 333 aa, and to Aeropyrum pernix farnesylgeranyl diphosphate synthase Fgs SWALL:Q9UWR6 (EMBL:AB025791) (318 aa) fasta scores: E(): 2.3e-07, 28.42% id in 299 aa NP_789483.1 Similar to Streptomyces coelicolor eukaryotic-type protain kinase PkaF SWALL:Q9ZNB3 (EMBL:AB019394) (629 aa) fasta scores: E(): 2.5e-38, 33.07% id in 638 aa NP_789484.1 Similar to Streptomyces coelicolor phospho-2-dehydro-3-deoxyheptonate aldolase AroH or SCO2115 or SC6E10.09c SWALL:AROF_STRCO (SWALL:P80574) (449 aa) fasta scores: E(): 3.3e-106, 59.17% id in 436 aa NP_789485.1 Similar to Streptomyces coelicolor putative acyltransferase SCO1228 or 2SCG1.03 SWALL:Q9FCD9 (EMBL:AL391014) (240 aa) fasta scores: E(): 7.8e-41, 47.03% id in 219 aa, and to Limnanthes alba 1-acyl-sn-glycerol-3-phosphate acyltransferase SWALL:PLSC_LIMAL (SWALL:Q42868) (281 aa) fasta scores: E(): 2.4e-07, 30% id in 160 aa NP_789486.1 Similar to Streptomyces coelicolor glucokinase GlkA or Glk or SCO2126 or SC6E10.20c SWALL:GLK_STRCO (SWALL:P40184) (317 aa) fasta scores: E(): 9.5e-28, 39.22% id in 311 aa NP_789487.1 No significant database matches. Probably membrane spanning. Contains 4 x 100bp (approx) repeat sequence in the C-terminal region from residue 324-736 approx. NP_789488.1 Similar to Rhizobium meliloti hypothetical transmembrane protein Smc00964 SWALL:Q92RI3 (EMBL:AL591785) (187 aa) fasta scores: E(): 1.6e-25, 49.42% id in 174 aa, and to Bacillus sphaericus biotin synthesis associated protein BioY SWALL:BIOY_BACSH (SWALL:P22819) (196 aa) fasta scores: E(): 4.6e-08, 30.05% id in 183 aa NP_789490.1 Weak but full length similarity to many oxidoreductases eg. Deinococcus radiodurans pyridine nucleotide-disulphide oxidoreductase, class II dr0412 SWALL:Q9RXA3 (EMBL:AE001901) (324 aa) fasta scores: E(): 7.1e-07, 23.26% id in 361 aa, and Borrelia burgdorferi thioredoxin reductase TrxB or bb0515 SWALL:TRXB_BORBU (SWALL:P94284) (326 aa) fasta scores: E(): 0.4, 22.43% id in 361 aa NP_789491.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_789492.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_789493.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_789494.1 Similar to Corynebacterium glutamicum acetohydroxy acid synthase, small subunit IlvN or LivS or cgl1272 SWALL:Q57091 (EMBL:L09232) (172 aa) fasta scores: E(): 1.9e-06, 45.12% id in 82 aa NP_789495.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate NP_789496.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_789497.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_789498.1 No significant database matches. 4x degenerate repeat at residue 650-1066. Exact 4x repeat at residue 1198-1555. Threonine-rich region residue 111-1171. NP_789499.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_789500.1 Similar to Mycobacterium tuberculosis cell division protein FtsX homolog or Rv3101c or mt3185 or mtcy164.12C SWALL:FTSX_MYCTU (SWALL:P96293) (297 aa) fasta scores: E(): 6.8e-15, 27.96% id in 304 aa, and to Streptomyces coelicolor putative cell division protein SCO2968 or SCE59.27c SWALL:Q9L1S7 (EMBL:AL138851) (305 aa) fasta scores: E(): 6.1e-37, 37.7% id in 305 aa NP_789501.1 Similar to Escherichia coli cell division ATP-binding protein FtsE or b3463 or z4837 or ecs4312 SWALL:FTSE_ECOLI (SWALL:P10115) (222 aa) fasta scores: E(): 4.8e-30, 50% id in 214 aa, and to Mycobacterium tuberculosis FtsE SWALL:P96292 (EMBL:X70031) (195 aa) fasta scores: E(): 5e-31, 58.42% id in 190 aa NP_789502.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_789503.1 Weakly similar to Listeria monocytogenes hypothetical protein Lmo1250 SWALL:Q8Y7M4 (EMBL:AL591978) (401 aa) fasta scores: E(): 4.4e-09, 21.61% id in 384 aa, and to Escherichia coli tetracycline resistance protein, class B TetA SWALL:TCR2_ECOLI (SWALL:P02980) (401 aa) fasta scores: E(): 1.3e-06, 21.82% id in 339 aa NP_789504.1 catalyzes the conversion of carbamoyl phosphate and aspartate to form N-carbamoyl aspartate NP_789507.1 Weakly similar to Rhizobium loti hypothetical protein Mll7596 mll7596 SWALL:Q985N7 (EMBL:AP003012) (148 aa) fasta scores: E(): 0.017, 29.41% id in 119 aa NP_789511.1 Similar to Pseudomonas aeruginosa probable type II secretion system protein Pa4302 SWALL:Q9HW98 (EMBL:AE004846) (421 aa) fasta scores: E(): 1.5e-39, 38.72% id in 346 aa, and to Actinobacillus actinomycetemcomitans tight adherance protein TadA SWALL:Q9XC06 (EMBL:AF152598) (426 aa) fasta scores: E(): 7.5e-36, 35.04% id in 371 aa NP_789512.1 Similar to Mycobacterium tuberculosis GlmU or Rv1018c or mt1046 or mtcy10g2.31 SWALL:P96382 (EMBL:Z92539) (513 aa) fasta scores: E(): 1.9e-42, 33% id in 606 aa, and to Bacillus subtilis UDP-N-acetylglucosamine pyrophosphorylase GcaD or Tms or Tms-26 SWALL:GCAD_BACSU (SWALL:P14192) (456 aa) fasta scores: E(): 4e-35, 28.04% id in 592 aa, and to Escherichia coli bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase GlmU or b3730 or z5228 or ecs4672 SWALL:GLMU_ECOLI (SWALL:P17114) (456 aa) fasta scores: E(): 1.3e-25, 27.48% id in 593 aa NP_789513.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_789514.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_789516.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_789517.1 Similar to Escherichia coli transcription-repair coupling factor Mfd or b1114 SWALL:MFD_ECOLI (SWALL:P30958) (1148 aa) fasta scores: E(): 1.1e-100, 32.02% id in 1168 aa, and to Streptomyces coelicolor putative transcriptional-repair coupling factor SCO3109 or SCE41.18c SWALL:Q9F2P1 (EMBL:AL442120) (1184 aa) fasta scores: E(): 3.8e-136, 39.79% id in 1161 aa NP_789518.1 Weakly similar to other putative membrane proteins eg. Vibrio cholerae hypothetical protein Vc2671 SWALL:Q9KNR0 (EMBL:AE004332) (460 aa) fasta scores: E(): 8.7e-09, 23.44% id in 482 aa NP_789519.1 Weakly similar to other putative membrane proteins eg. Archaeoglobus fulgidus daunorubicin resistance membrane protein af1883 SWALL:O28396 (EMBL:AE000972) (251 aa) fasta scores: E(): 0.0039, 24.51% id in 257 aa NP_789520.1 Similar to many putative ABC transporter ATP-binding proteins eg. Caulobacter crescentus ABC transporter, ATP-binding protein cc1147 SWALL:Q9A947 (EMBL:AE005793) (328 aa) fasta scores: E(): 4.3e-20, 32.18% id in 289 aa NP_789522.1 Similar to Fusobacterium nucleatum ABC transporter ATP-binding protein Fn1352 SWALL:Q8RDY9 (EMBL:AE010640) (224 aa) fasta scores: E(): 7.7e-18, 35.61% id in 219 aa, and to Escherichia coli cell division ATP-binding protein FtsE or b3463 or z4837 or ecs4312 SWALL:FTSE_ECOLI (SWALL:P10115) (222 aa) fasta scores: E(): 8.4e-15, 32.86% id in 216 aa NP_789524.1 Similar to Pseudomonas aeruginosa hypothetical protein Pa2988 SWALL:Q9HZL6 (EMBL:AE004724) (416 aa) fasta scores: E(): 0.00022, 24.59% id in 374 aa NP_789526.1 Doubtful CDS. No significant database matches NP_789527.1 Doubtful CDS. No significant database matches NP_789528.1 Doubtful CDS. No significant database matches. Contains variable length tandem repeat. NP_789529.1 Doubtful CDS. No significant database matches NP_789530.1 Similar to Escherichia coli tyrosyl-tRNA synthetase TyrS or b1637 or z2650 or ecs2346 SWALL:SYY_ECOLI (SWALL:P00951) (423 aa) fasta scores: E(): 6.5e-61, 48.43% id in 351 aa, and to Streptomyces coelicolor tyrosyl-tRNA synthetase TyrS or SCO1818 or SCI8.03 SWALL:Q9RJ50 (EMBL:AL132644) (422 aa) fasta scores: E(): 1.2e-78, 49.35% id in 464 aa NP_789531.1 Similar to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT or b1713 SWALL:SYFB_ECOLI (SWALL:P07395) (795 aa) fasta scores: E(): 2.6e-45, 28.75% id in 845 aa, and to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or mt1688 or mtcy06h11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 1.1e-50, 32.78% id in 976 aa NP_789532.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_789533.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_789534.2 Similar to Escherichia coli 50s ribosomal protein L35 RpmI or b1717 or z2746 or ecs2424 or stm1335 or sty1776 SWALL:RL35_ECOLI (SWALL:P07085) (64 aa) fasta scores: E(): 0.0013, 39.62% id in 53 aa, and to Streptomyces coelicolor 50s ribosomal protein L35 RpmI or SCO1599 or SCI35.21c SWALL:RL35_STRCO (SWALL:O88059) (64 aa) fasta scores: E(): 9.6e-14, 62.5% id in 64 aa NP_789535.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_789536.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_789538.1 Similar to Clostridium acetobutylicum glycosyltransferase domain containing protein Cac2327 SWALL:Q97GN9 (EMBL:AE007733) (1044 aa) fasta scores: E(): 2.9e-67, 33.03% id in 666 aa C-terminal region similar to Clostridium acetobutylicum diverged glycosyltransferase domain containing protein Cac2326 SWALL:Q97GP0 (EMBL:AE007733) (436 aa) fasta scores: E(): 1.6e-59, 37.91% id in 451 aa. N-terminal region contains match to Pfam entry PF00534 Glycosyl transferases group 1 and is similar to Porphyromonas gingivalis orf1, orf2 and orf3 genes SWALL:P72199 (EMBL:U60208) (322 aa) fasta scores: E(): 0.36, 24.01% id in 279 aa NP_789539.1 Similar to Escherichia coli ribosome-binding factor A RbfA or p15b or b3167 or z4528 or ecs4048 SWALL:RBFA_ECOLI (SWALL:P09170) (132 aa) fasta scores: E(): 0.0053, 27.82% id in 115 aa, and to Corynebacterium glutamicum ribosome-binding factor A cgl1984 SWALL:BAB99377 (EMBL:AP005280) (149 aa) fasta scores: E(): 1.2e-10, 38.25% id in 149 aa, and to Streptococcus agalactiae ribosome binding factor A RbfA SWALL:Q9ZF19 (EMBL:AJ003164) (122 aa) fasta scores: E(): 0.0027, 31.57% id in 114 aa NP_789540.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_789541.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_789542.1 Doubtful CDS. No significant database matches NP_789543.1 Similar to Corynebacterium glutamicum uncharacterized Acr cgl0233 SWALL:BAB97626 (EMBL:AP005274) (246 aa) fasta scores: E(): 1.8e-21, 35.64% id in 202 aa, and to Chlamydia pneumoniae conserved hypothetical bacterial membrane protein cpn1045 or cpj1045 SWALL:Q9Z6L4 (EMBL:AE001685) (230 aa) fasta scores: E(): 3.2e-11, 28.98% id in 207 aa NP_789544.1 Similar to Escherichia coli inorganic pyrophosphatase Ppa or b4226 or z5837 or ecs5204 SWALL:IPYR_ECO57 (SWALL:P17288) (175 aa) fasta scores: E(): 4.4e-26, 48.12% id in 160 aa NP_789546.1 Similar to Escherichia coli queuine tRNA-ribosyltransferase Tgt or b0406 or z0505 or ecs0457 SWALL:TGT_ECO57 (SWALL:P19675) (375 aa) fasta scores: E(): 1.2e-33, 37.77% id in 368 aa, and to Zymomonas mobilis queuine tRNA-ribosyltransferase Tgt SWALL:TGT_ZYMMO (SWALL:P28720) (385 aa) fasta scores: E(): 6.2e-35, 37.05% id in 394 aa NP_789548.1 C-terminal region similar to others eg. Streptomyces coelicolor putative NLP/P60 family secreted protein SCO4561 or SCD16A.22 SWALL:Q9XAQ3 (EMBL:AL078618) (277 aa) fasta scores: E(): 3.5e-11, 33.33% id in 207 aa NP_789549.1 Doubtful CDS. No significant database matches NP_789550.1 No significant database matches. Pro/Ala/Ser/Thr-rich. NP_789551.1 No significant database matches. Pro/Ala/Ser/Thr-rich. NP_789552.1 Similar to Escherichia coli tRNA delta (2)-isopentenylpyrophosphate transferase MiaA or TrpX or b4171 SWALL:MIAA_SHIFL (SWALL:P16384) (316 aa) fasta scores: E(): 2.9e-18, 29.49% id in 278 aa, and to Streptomyces coelicolor trna delta (2)-isopentenylpyrophosphate transferase MiaA or SCO5791 or SC4H2.12 SWALL:MIAA_STRCO (SWALL:O69967) (312 aa) fasta scores: E(): 7.8e-35, 42.59% id in 270 aa NP_789553.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_789554.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_789555.1 Similar to Bacillus subtilis CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA SWALL:PGSA_BACSU (SWALL:P46322) (193 aa) fasta scores: E(): 3.8e-11, 40.54% id in 148 aa NP_789557.1 Similar to Streptomyces coelicolor Ftsk homolog SCO5750 or SC7C7.05 SWALL:O86810 (EMBL:AL031031) (929 aa) fasta scores: E(): 1.9e-111, 46.58% id in 848 aa, and to Bacillus subtilis stage III sporulation protein E SpoIIIE SWALL:SP3E_BACSU (SWALL:P21458) (787 aa) fasta scores: E(): 1e-79, 46.84% id in 491 aa NP_789558.1 Similar to Streptomyces coelicolor hypothetical protein SCO5745 or SC9A10.09 SWALL:O86842 (EMBL:AL031260) (561 aa) fasta scores: E(): 1.8e-112, 53.95% id in 543 aa NP_789559.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_789561.1 Similar to Streptomyces coelicolor hypothetical protein WblE or SCO5240 or 2SC7G11.02c SWALL:Q9X952 (EMBL:AJ239087) (85 aa) fasta scores: E(): 2.3e-20, 64.28% id in 84 aa, and to Streptomyces griseocarneus WhiB-STV protein SWALL:Q06387 (EMBL:X68708) (87 aa) fasta scores: E(): 1.4e-08, 43.83% id in 73 aa, and to Mycobacterium smegmatis WhmD SWALL:Q9S426 (EMBL:AF164439) (129 aa) fasta scores: E(): 1.4e-08, 45.07% id in 71 aa NP_789562.1 Doubtful CDS. No significant database matches. Pro/Ala-rich. NP_789563.1 Similar to Streptomyces coelicolor possible membrane protein SCO3411 or SCE9.18c SWALL:Q9X8J1 (EMBL:AL049841) (303 aa) fasta scores: E(): 7.9e-28, 41.03% id in 212 aa, and to Escherichia coli DedA protein or b2317 or z3579 or ecs3201 SWALL:DEDA_ECO57 (SWALL:P09548) (219 aa) fasta scores: E(): 2.2e-21, 34.27% id in 213 aa NP_789564.1 Similar to Streptomyces coelicolor Ham1 protein homolog SCO2902 or SCE19A.02c SWALL:HAM1_STRCO (SWALL:Q9S2H9) (200 aa) fasta scores: E(): 2e-25, 42.78% id in 194 aa NP_789565.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_789566.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_789567.1 No significant database matches. Rep6. Frameshifted at potentially variable C(11) tract after aa 24 NP_789568.1 No significant database matches. Note possible downstream alternative start codons. NP_789569.1 Similar to Streptomyces coelicolor hypothetical protein SCO5204 or 2SC3B6.28 or SC7E4.01 SWALL:YGA4_STRCO (SWALL:Q9FCI4) (1000 aa) fasta scores: E(): 6.2e-99, 40.08% id in 978 aa, and to Bifidobacterium longum NCC2705 narrowly conserved hypothetical protein bl1029 SWALL:AAN24835 (EMBL:AE014726) (1066 aa) fasta scores: E(): 2.9e-86, 42.56% id in 1015 aa NP_789570.1 Similar to Corynebacterium glutamicum predicted secreted protein containing a PDZ domain cgl0783 SWALL:Q8NS96 (EMBL:AP005276) (350 aa) fasta scores: E(): 5.2e-19, 29.67% id in 310 aa NP_789571.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide NP_789572.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate NP_789573.1 Similar to Caulobacter crescentus chromosome partitioning protein ParA or cc3753 SWALL:PARA_CAUCR (SWALL:O05189) (267 aa) fasta scores: E(): 2.8e-13, 30.34% id in 234 aa, and to Streptomyces coelicolor ParA SWALL:Q9RFM1 (EMBL:AF187159) (357 aa) fasta scores: E(): 2.8e-11, 29.2% id in 226 aa NP_789575.1 Similar to many predicted histidine kinases eg. Bifidobacterium longum NCC2705 histidine kinase-like protein bl1012 SWALL:AAN24820 (EMBL:AE014724) (510 aa) fasta scores: E(): 6.6e-53, 35.72% id in 459 aa NP_789576.1 Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 2.6e-54, 38.88% id in 414 aa, and to Streptomyces coelicolor putative 4-aminobutyrate aminotransferase GabT or SCO5676 or SC8B7.02 SWALL:O86823 (EMBL:AL031225) (444 aa) fasta scores: E(): 5.6e-65, 46.92% id in 439 aa NP_789577.1 Similar to Bacillus subtilis FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] FolD SWALL:FOLD_BACSU (SWALL:P54382) (283 aa) fasta scores: E(): 1.9e-37, 42.4% id in 283 aa, and to Streptomyces coelicolor bifunctional protein FolD or SCO4824 or SC2A6.09 SWALL:Q9K3J6 (EMBL:AL389898) (284 aa) fasta scores: E(): 1.9e-46, 46.45% id in 282 aa NP_789578.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_789579.1 Similar to Clostridium perfringens hypothetical protein Cpe1730 SWALL:Q8XJM6 (EMBL:AP003191) (185 aa) fasta scores: E(): 1.7e-16, 38.17% id in 186 aa, and to Escherichia coli putative methylase YhhF or b3465 SWALL:YHHF_ECOLI (SWALL:P10120) (198 aa) fasta scores: E(): 1.1e-11, 36.26% id in 182 aa NP_789580.1 Similar to Streptomyces coelicolor probable glycine cleavage system H protein GcvH or SCO5471 or SC2A11.05c SWALL:GCSH_STRCO (SWALL:O86566) (125 aa) fasta scores: E(): 3.4e-16, 44.26% id in 122 aa NP_789581.1 Similar to Escherichia coli aminomethyltransferase GcvT or b2905 SWALL:GCST_ECOLI (SWALL:P27248) (363 aa) fasta scores: E(): 2.1e-27, 34.9% id in 361 aa, and to Streptomyces coelicolor probable aminomethyltransferase GcvT or SCO5472 or SC2A11.06c SWALL:GCST_STRCO (SWALL:O86567) (372 aa) fasta scores: E(): 1.9e-39, 43.81% id in 372 aa NP_789582.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_789583.1 Similar to Zymomonas mobilis DNA recombination protein RmuC homolog SWALL:RMUC_ZYMMO (SWALL:Q9REQ3) (448 aa) fasta scores: E(): 2.3e-22, 27.41% id in 383 aa NP_789585.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_789586.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_789587.1 Similar to Streptomyces coelicolor probable exodeoxyribonuclease VII small subunit XseB or SCO5055 or SCK7.28c SWALL:EX7S_STRCO (SWALL:Q9FBM4) (88 aa) fasta scores: E(): 0.0014, 40.62% id in 64 aa, and to Paracoccus zeaxanthinifaciens exonuclease VII small subunit XseB SWALL:CAD24424 (EMBL:AJ431697) (78 aa) fasta scores: E(): 2.7, 37.25% id in 51 aa NP_789588.1 Similar to Escherichia coli probable glucarate transporter GudP or b2789 SWALL:GUDP_ECOLI (SWALL:Q46916) (450 aa) fasta scores: E(): 2.4e-37, 32.04% id in 415 aa NP_789589.1 Similar to Haloferax sp. 2-keto-3-deoxygluconate kinase SWALL:P94803 (EMBL:U70664) (318 aa) fasta scores: E(): 3.1e-23, 32.43% id in 296 aa, and to Bacillus stearothermophilus 2-keto-3-deoxy-gluconate kinase KdgK SWALL:Q9ZFM1 (EMBL:AF098273) (314 aa) fasta scores: E(): 3.5e-12, 28.3% id in 265 aa NP_789590.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate NP_789591.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway NP_789592.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization NP_789593.1 Similar to Mycoplasma pulmonis hypothetical protein Mypu_5930 SWALL:Q98PX6 (EMBL:AL445565) (351 aa) fasta scores: E(): 4.9e-39, 36.02% id in 322 aa NP_789594.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_789596.1 Doubtful CDS. No significant database matches NP_789598.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_789599.1 Similar to Zymomonas mobilis phosphoglycerate mutase Gpm or Pgm SWALL:PMGY_ZYMMO (SWALL:P30798) (228 aa) fasta scores: E(): 3.5e-37, 52.33% id in 214 aa NP_789600.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv0811c or mtv043.03c or mt0832 SWALL:O53825 (EMBL:AL022004) (368 aa) fasta scores: E(): 2.9e-17, 32.1% id in 352 aa NP_789601.1 Doubtful CDS. No significant database matches NP_789602.1 Similar to Corynebacterium glutamicum hypothetical membrane protein Cgl0809 SWALL:Q8NS70 (EMBL:AP005276) (196 aa) fasta scores: E(): 3.4e-15, 41.73% id in 127 aa NP_789603.1 Similar to Streptomyces coelicolor putative acetyltransferase SCO4151 or SCD84.18c SWALL:Q9KZV0 (EMBL:AL353816) (309 aa) fasta scores: E(): 5.2e-15, 31.9% id in 257 aa, and to Streptomyces lavendulae streptothricin acetyltransferase Sta SWALL:STA_STRLA (SWALL:P08457) (189 aa) fasta scores: E(): 0.58, 27.38% id in 84 aa NP_789604.1 Similar to Mycobacterium tuberculosis hypothetical 34.7 kDa protein mutt1 or rv2985 or mtcy349.02c or mt3063 SWALL:P95110 (EMBL:Z83018) (317 aa) fasta scores: E(): 0.013, 29.66% id in 300 aa NP_789605.1 Similar to Mycobacterium tuberculosis large-conductance mechanosensitive channel MscL or Rv0985c or mt1013 or mtv044.13C SWALL:MSCL_MYCTU (SWALL:O53898) (151 aa) fasta scores: E(): 1.2e-06, 37.62% id in 101 aa NP_789606.1 Similar to Synechocystis sp. periplasmic-binding protein MntC or sll1598 SWALL:Q55280 (EMBL:L34630) (330 aa) fasta scores: E(): 6.3e-36, 38.06% id in 289 aa NP_789607.1 Similar to Synechocystis sp. manganese transport system ATP-binding protein MntA or sll1599 SWALL:MNTA_SYNY3 (SWALL:Q55281) (260 aa) fasta scores: E(): 6.6e-34, 46.18% id in 236 aa NP_789608.1 Similar to Synechocystis sp. manganese transport system membrane protein MntB or sll1600 SWALL:MNTB_SYNY3 (SWALL:Q55282) (306 aa) fasta scores: E(): 6.7e-40, 43.41% id in 258 aa NP_789609.1 No significant database matches. NP_789611.1 Similar to Aquifex aeolicus hypothetical protein Aq_1731 SWALL:O67621 (EMBL:AE000753) (186 aa) fasta scores: E(): 2.9e-10, 33.71% id in 175 aa NP_789612.1 Weak but full length similarity to Bifidobacterium longum NCC2705 large hypothetical protein bl1552 SWALL:AAN25344 (EMBL:AE014790) (1207 aa) fasta scores: E(): 1.3e-24, 23.73% id in 1201 aa NP_789613.1 Similar to Deinococcus radiodurans hypothetical protein Dr2265 SWALL:Q9RS62 (EMBL:AE002059) (725 aa) fasta scores: E(): 2.1e-42, 42.99% id in 728 aa NP_789615.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_789616.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_789617.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_789618.1 Doubtful CDS. No significant database matches NP_789620.1 Similar to Escherichia coli transcription elongation factor GreA or b3181 SWALL:GREA_ECOLI (SWALL:P21346) (158 aa) fasta scores: E(): 1.6e-05, 30.76% id in 143 aa, and to Mycobacterium tuberculosis transcription elongation factor GreA or Rv1080c or mt1111 or mtv017.33C SWALL:GREA_MYCTU (SWALL:O53428) (164 aa) fasta scores: E(): 7.4e-18, 42.33% id in 163 aa NP_789621.1 Similar to Salmonella typhimurium threonine dehydratase catabolic TdcB or stm3244 SWALL:THD2_SALTY (SWALL:P11954) (329 aa) fasta scores: E(): 3.5e-20, 36.93% id in 333 aa, and to Streptomyces coelicolor putative amino acid deaminase SCO4962 or 2SCK31.22 SWALL:Q9EWG3 (EMBL:AL512667) (409 aa) fasta scores: E(): 2.8e-30, 41.66% id in 420 aa NP_789622.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_789623.1 Catalyzes the rate-limiting step in dNTP synthesis NP_789625.1 Similar to Corynebacterium glutamicum exonuclease III cgl0671 SWALL:Q8NSK0 (EMBL:AP005276) (304 aa) fasta scores: E(): 1.6e-10, 39.87% id in 316 aa, and to Bos taurus DNA-(apurinic or apyrimidinic site) lyase ApeX1 or ApeX or Ape or Bap1 SWALL:APE1_BOVIN (SWALL:P23196) (317 aa) fasta scores: E(): 0.002, 28.67% id in 286 aa NP_789626.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_789627.1 Similar to Escherichia coli riboflavin biosynthesis protein RibD [includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (riboflavin-specific deaminase); 5-amino-6-(5- phosphoribosylamino)uracil reductase (EC 1.1.1.193) (htp reductase)] RibD or RibG or b0414 SWALL:RIBD_ECOLI (SWALL:P25539) (367 aa) fasta scores: E(): 4.6e-20, 33.52% id in 358 aa NP_789628.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_789629.1 Similar to Escherichia coli 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB SWALL:RIBB_ECO57 (SWALL:P24199) (217 aa) fasta scores: E(): 2.6e-29, 43.78% id in 201 aa, and to Streptomyces coelicolor 3,4-dihydroxy-2-butanone 4-phosphate synthase RibA or SCO1441 or SC6D7A.04c SWALL:Q9EWJ8 (EMBL:AL450443) (429 aa) fasta scores: E(): 1.6e-32, 47% id in 200 aa NP_789630.1 Similar to Streptomyces coelicolor GTP cyclohydrolase II RibA or SCO6655 or SC5A7.05 SWALL:GCH2_STRCO (SWALL:O88011) (221 aa) fasta scores: E(): 5.3e-34, 52.12% id in 188 aa, and to Arabidopsis thaliana GTP cyclohydrolase II SWALL:GCH2_ARATH (SWALL:P47924) (245 aa) fasta scores: E(): 1.3e-31, 47.54% id in 183 aa NP_789631.1 Similar to Aquifex aeolicus 6,7-dimethyl-8-ribityllumazine synthase RibH or aq_132 SWALL:RISB_AQUAE (SWALL:O66529) (154 aa) fasta scores: E(): 1.7e-11, 36.69% id in 139 aa NP_789632.1 Similar to Mycobacterium tuberculosis pyrazinamidase/nicotinamidase PncA or Rv2043c or mtv018.30c or mt2103 SWALL:Q50575 (EMBL:U59967) (186 aa) fasta scores: E(): 1.6e-28, 43.85% id in 187 aa NP_789633.1 Similar to Streptomyces lividans proteinase slpE SWALL:Q54399 (EMBL:L42759) (513 aa) fasta scores: E(): 1.6e-39, 34.32% id in 536 aa NP_789634.1 Similar to Streptomyces coelicolor putative DNA polymerase SCO3541 or SCH5.03C SWALL:Q9X906 (EMBL:AL035636) (401 aa) fasta scores: E(): 1.2e-25, 30.36% id in 359 aa NP_789635.1 Similar to Bacillus halodurans thymidylate kinase tmk or bh0042 SWALL:KTHY_BACHD (SWALL:Q9KGL9) (210 aa) fasta scores: E(): 1.9e-21, 40.39% id in 203 aa NP_789636.1 Similar to Escherichia coli DNA topoisomerase I TopA or SupX or b1274 SWALL:TOP1_ECOLI (SWALL:P06612) (865 aa) fasta scores: E(): 3e-47, 36.55% id in 766 aa, and to Bifidobacterium longum NCC2705 DNA topoisomerase i topA SWALL:AAN24314 (EMBL:AE014668) (1030 aa) fasta scores: E(): 2.9e-49, 45.38% id in 932 aa NP_789641.1 Similar to Corynebacterium glutamicum predicted ATPases involved in pili and flagella biosynthesis, VirB11 family cgl0301 SWALL:Q8NTK6 (EMBL:AP005274) (341 aa) fasta scores: E(): 2.9e-40, 43.18% id in 301 aa, and to Actinobacillus actinomycetemcomitans TadA SWALL:Q9XC06 (EMBL:AF152598) (426 aa) fasta scores: E(): 7e-36, 37.33% id in 308 aa NP_789642.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3678c or Mtv025.026c or mt3779 SWALL:O69646 (EMBL:AL022121) (151 aa) fasta scores: E(): 3e-25, 55.47% id in 146 aa NP_789643.1 Similar to Bifidobacterium longum NCC2705 possible penicillin-binding protein bl1215 SWALL:AAN25022 (EMBL:AE014747) (771 aa) fasta scores: E(): 1e-29, 32.76% id in 766 aa, and to Mycobacterium leprae Pbp1 Pon1 SWALL:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 1.1e-08, 27.82% id in 823 aa NP_789644.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv3683 or mtv025.031 or mt3785 SWALL:O69651 (EMBL:AL022121) (319 aa) fasta scores: E(): 1.1e-45, 44.29% id in 289 aa NP_789645.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_789646.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_789647.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_789648.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_789649.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_789650.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_789651.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_789652.1 binds directly to 23S ribosomal RNA NP_789653.1 Similar to Streptomyces griseus transcription antitermination protein NusG SWALL:NUSG_STRGR (SWALL:P36260) (294 aa) fasta scores: E(): 3e-35, 48.27% id in 203 aa NP_789654.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_789655.1 Similar to Escherichia coli UDP-N-acetylenolpyruvoylglucosamine reductase MurB or b3972 SWALL:MURB_ECOLI (SWALL:P08373) (342 aa) fasta scores: E(): 1.4e-08, 31.05% id in 351 aa, and to Mycobacterium tuberculosis UDP-N-acetylenolpyruvoylglucosamine reductase MurB or Rv0482 or mt0500 or mtcy20g9.08 SWALL:MURB_MYCTU (SWALL:Q11148) (369 aa) fasta scores: E(): 6.7e-32, 38.04% id in 368 aa NP_789656.1 Similar to Streptomyces coelicolor hypothetical protein SCO4637 or SCD82.08 SWALL:Q9L0M3 (EMBL:AL160431) (142 aa) fasta scores: E(): 6e-11, 38.4% id in 138 aa NP_789657.1 Similar to Streptomyces coelicolor hypothetical protein sco4636 sco4636 or scd82.07 SWALL:Q9L0M4 (EMBL:AL160431) (150 aa) fasta scores: E(): 8.7e-08, 42.22% id in 90 aa NP_789658.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_789659.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_789660.1 Similar to Bacillus subtilis phosphoribosylamine--glycine ligase purD SWALL:PUR2_BACSU (SWALL:P12039) (422 aa) fasta scores: E(): 4.5e-44, 41.19% id in 420 aa NP_789661.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_789662.1 Similar to Streptomyces coelicolor hypothetical protein SCO4581 or SCD16A.02c SWALL:Q9XAS3 (EMBL:AL078618) (269 aa) fasta scores: E(): 6.9e-07, 27.2% id in 272 aa NP_789663.1 Similar to Streptomyces coelicolor putative transcriptional regulator SCO6020 or SC1C3.08c SWALL:O69850 (EMBL:AL023702) (366 aa) fasta scores: E(): 1.1e-30, 34.68% id in 346 aa NP_789664.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_789665.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_789666.1 Similar to Clostridium josui porphyrin biosynthesis protein HemD [includes: uroporphyrin-iii c- methyltransferase (EC 2.1.1.107) (urogen iii methylase)(sumt)(uroporphyrinogen iii methylase) (urom); uroporphyrinogen-iii synthase (EC 4.2.1.75) (uros) (uroporphyrinogen-iii cosynthetase) (hydroxymethylbilane hydrolyase [cyclizing])] SWALL:HEM4_CLOJO (SWALL:Q59294) (504 aa) fasta scores: E(): 0.57, 23.22% id in 254 aa, and to Deinococcus radiodurans uroporphyrinogen-III synthase, putative dr0786 SWALL:Q9RW83 (EMBL:AE001933) (257 aa) fasta scores: E(): 1.8e-06, 29.08% id in 251 aa NP_789667.1 Similar to Escherichia coli porphobilinogen deaminase HemC or PopE or b3805 SWALL:HEM3_ECOLI (SWALL:P06983) (313 aa) fasta scores: E(): 1.1e-20, 34.84% id in 330 aa NP_789668.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_789669.1 Similar to Streptomyces coelicolor hypothetical protein SCO6042 or SC1B5.02 SWALL:O69830 (EMBL:AL023517) (243 aa) fasta scores: E(): 5.8e-36, 49.45% id in 184 aa NP_789670.1 Similar to Mycobacterium tuberculosis uroporphyrinogen decarboxylase HemE or Rv2678c or mt2752 or mtv010.02C SWALL:DCUP_MYCTU (SWALL:O53231) (357 aa) fasta scores: E(): 5.9e-45, 42.81% id in 362 aa, and to Mus musculus uroporphyrinogen decarboxylase UroD SWALL:Q91VW4 (EMBL:BC008109) (367 aa) fasta scores: E(): 2.9e-36, 35.59% id in 354 aa NP_789671.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_789672.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate NP_789673.1 Similar to Escherichia coli replicative DNA helicase DnaB or GroP or GrpA or b4052 SWALL:DNAB_ECOLI (SWALL:P03005) (471 aa) fasta scores: E(): 4.2e-57, 38.39% id in 448 aa, and to Streptomyces coelicolor putative replicative DNA helicase DnaB or SCO3911 or SCH24.33 SWALL:Q9X8U7 (EMBL:AL049826) (491 aa) fasta scores: E(): 9.8e-88, 53.34% id in 433 aa NP_789674.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob2412 SWALL:BAC14368 (EMBL:AP004601) (194 aa) fasta scores: E(): 0.00011, 23.56% id in 191 aa NP_789675.1 Similar to Escherichia coli NagD protein NagD or b0675 or z0822 or ecs0705 SWALL:NAGD_ECOLI (SWALL:P15302) (250 aa) fasta scores: E(): 1.8e-34, 41.46% id in 246 aa, and to Streptomyces coelicolor hypothetical protein SCO2843 or SCE20.17c SWALL:Q9RDA8 (EMBL:AL136058) (259 aa) fasta scores: E(): 9.8e-58, 57.81% id in 256 aa NP_789676.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_789677.1 Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 6.5e-17, 29.93% id in 284 aa, and to Caulobacter crescentus exodeoxyribonuclease III cc2011 SWALL:Q9A6S2 (EMBL:AE005874) (262 aa) fasta scores: E(): 4.8e-33, 39.41% id in 274 aa NP_789678.1 No significant database matches. Note overlap with downstteam CDS. NP_789679.1 Similar to Streptomyces albus G heat shock protein ClpB SWALL:Q9Z6E4 (EMBL:AF076980) (857 aa) fasta scores: E(): 2.9e-134, 59.62% id in 686 aa. Note approx 150 residue N-termunal truncation relative to all homologues. NP_789680.1 Similar to Streptomyces coelicolor putative heat shock protein HspR or SCO3668 or SCH44.08c SWALL:HSPR_STRCO (SWALL:P40183) (151 aa) fasta scores: E(): 2.6e-11, 40.15% id in 132 aa, and to Streptomyces albus G HspR SWALL:P96458 (EMBL:U43299) (154 aa) fasta scores: E(): 5.6e-10, 39.41% id in 137 aa NP_789681.1 Similar to Streptomyces coelicolor chaperone protein DnaJ or SCO3669 or SCH44.09c SWALL:DNAJ_STRCO (SWALL:P40170) (399 aa) fasta scores: E(): 3.5e-17, 30.82% id in 399 aa, and to Escherichia coli curved DNA-binding protein CbpA or b1000 SWALL:CBPA_ECOLI (SWALL:P36659) (306 aa) fasta scores: E(): 1.5e-20, 40.19% id in 301 aa, and to Escherichia coli chaperone protein DnaJ or GroP or b0015 SWALL:DNAJ_ECOLI (SWALL:P08622) (375 aa) fasta scores: E(): 5.1e-13, 31.32% id in 348 aa NP_789682.1 Similar to Streptomyces coelicolor GrpE protein or SCO3670 or SCH44.10c SWALL:GRPE_STRCO (SWALL:Q05562) (225 aa) fasta scores: E(): 1.3e-12, 33.16% id in 196 aa, and to Bacillus thermoglucosidasius GrpE protein SWALL:Q9KWS8 (EMBL:AB017035) (224 aa) fasta scores: E(): 2.8e-08, 30.81% id in 185 aa, and to Leptospira interrogans GrpE protein SWALL:GRPE_LEPIN (SWALL:O51868) (212 aa) fasta scores: E(): 1.6e-07, 28.85% id in 201 aa NP_789683.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_789684.1 Similar to many of undefined function eg. Streptomyces coelicolor putative deaminase SCO4038 or 2SCD60.04c SWALL:Q9AK79 (EMBL:AL583944) (143 aa) fasta scores: E(): 4.2e-25, 52.11% id in 142 aa, and to Mycobacterium tuberculosis hypothetical 15.9 kDa protein Rv3752c or mtv025.100c or mt3859 SWALL:O69719 (EMBL:AL022121) (152 aa) fasta scores: E(): 1.3e-24, 52% id in 150 aa NP_789685.1 Similar to Escherichia coli pyrroline-5-carboxylate reductase ProC or b0386 SWALL:PROC_ECOLI (SWALL:P00373) (269 aa) fasta scores: E(): 5.8e-11, 25.45% id in 275 aa NP_789687.1 Similar to Pyrococcus kodakaraensis aspartyl-tRNA synthetase AspS SWALL:SYD_PYRKO (SWALL:Q52428) (438 aa) fasta scores: E(): 1.8e-60, 39.63% id in 434 aa NP_789688.1 Similar to Streptomyces coelicolor putative phosphoglycerate mutase SCO4470 or SCD65.13 SWALL:Q9F2R9 (EMBL:AL392176) (233 aa) fasta scores: E(): 9.5e-34, 45.12% id in 195 aa NP_789690.1 Similar to Bacillus subtilis cytochrome c-type biogenesis protein CcdA SWALL:CCDA_BACSU (SWALL:P45706) (235 aa) fasta scores: E(): 1.7e-09, 26.4% id in 231 aa, and to Rhodobacter capsulatus c-type cytochrome biogenesis protein CcdA SWALL:Q9LA04 (EMBL:AF156103) (252 aa) fasta scores: E(): 2.7e-12, 32.8% id in 253 aa NP_789691.1 Similar to Streptomyces coelicolor putative integral membrane protein SCO4474 or SCD65.17 SWALL:Q9F2R5 (EMBL:AL392176) (574 aa) fasta scores: E(): 1.8e-16, 37.09% id in 523 aa NP_789692.1 Similar to Aquifex aeolicus cytochrome c biogenesis protein HemX2 or aq_2043 SWALL:O67831 (EMBL:AE000769) (312 aa) fasta scores: E(): 3.7e-27, 33.58% id in 262 aa, and to Chlamydomonas reinhardtii cytochrome c biogenesis protein CcsA SWALL:CCSA_CHLRE (SWALL:P48269) (353 aa) fasta scores: E(): 4.9e-22, 29.43% id in 299 aa NP_789693.1 No significant database matches. Rep6. NP_789696.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_789698.1 Similar to Streptomyces coelicolor putative glycosyl transferase SCO1423 or SC6D7.16 SWALL:Q9RKY2 (EMBL:AL133213) (302 aa) fasta scores: E(): 6.1e-44, 49.15% id in 236 aa, and to Mus musculus dolichol-phosphate mannosyltransferase Dpm1 SWALL:DPM1_MOUSE (SWALL:O70152) (260 aa) fasta scores: E(): 3.7e-24, 37.6% id in 234 aa NP_789699.1 Doubtful CDS. No significant database matches. Note possible doubtful CDS on opposite strand. NP_789700.1 Weakly similar to Mycobacterium leprae putative membrane protein Ml2296 SWALL:Q9CB97 (EMBL:AL583925) (181 aa) fasta scores: E(): 0.039, 32.06% id in 131 aa NP_789701.1 N-terminus similar to that of Streptomyces coelicolor putative secreted protein SCO2461 or SCC24.32 SWALL:Q9L085 (EMBL:AL163003) (108 aa) fasta scores: E(): 0.73, 39.13% id in 46 aa NP_789702.1 Similar to many predicted peptidases eg. Mycobacterium tuberculosis zinc metalloprotease Rv0198c or mtv033.06c or mt0208 SWALL:O53649 (EMBL:AL021928) (663 aa) fasta scores: E(): 8e-92, 44.16% id in 668 aa NP_789703.1 Similar to Alcaligenes eutrophus phosphoglycolate phosphatase, chromosomal CbbZC SWALL:GPHC_ALCEU (SWALL:P40852) (231 aa) fasta scores: E(): 1.1e-12, 33.33% id in 228 aa NP_789704.1 Similar to Rhodobacter sphaeroides modification methylase RsrI RsrIM SWALL:MTR1_RHOSH (SWALL:P14751) (319 aa) fasta scores: E(): 3.3e-14, 32.82% id in 262 aa NP_789705.1 Similar to Bifidobacterium longum NCC2705 hypothetical protein with Fha domain bl0583 SWALL:AAN24407 (EMBL:AE014680) (233 aa) fasta scores: E(): 8.6e-05, 29.51% id in 227 aa NP_789706.1 Similar to Corynebacterium glutamicum FHA-domain-containing proteins cgl0046 SWALL:Q8NU93 (EMBL:AP005274) (154 aa) fasta scores: E(): 3.9e-10, 29.67% id in 155 aa NP_789707.1 Similar to Streptomyces coelicolor putative FtsW/RodA/SpoVE family cell cycle protein SCO3846 or SCH69.16 SWALL:Q9XA18 (EMBL:AL079308) (479 aa) fasta scores: E(): 6.7e-49, 38.46% id in 442 aa, and to Bacillus subtilis stage V sporulation protein E SpoVE SWALL:SP5E_BACSU (SWALL:P07373) (366 aa) fasta scores: E(): 6.2e-21, 30.13% id in 365 aa NP_789708.1 Similar to Streptomyces griseus PbpA SWALL:Q9L656 (EMBL:AF241575) (485 aa) fasta scores: E(): 1.3e-40, 33.47% id in 487 aa NP_789709.1 Similar to many predicted serine/threonine-protein kinases eg. Mycobacterium tuberculosis probable serine/threonine-protein kinase PknA or Rv0015c or mt0018 or mtcy10h4.15C SWALL:PKNA_MYCTU (SWALL:P71585) (431 aa) fasta scores: E(): 1.1e-39, 44.9% id in 363 aa NP_789710.1 Similar to many predicted serine/threonine-protein kinases eg. Mycobacterium leprae probable serine/threonine-protein kinase pknb pknb or ml0016 SWALL:PKNB_MYCLE (SWALL:P54744) (622 aa) fasta scores: E(): 7.7e-08, 25.27% id in 459 aa NP_789711.1 Similar to Streptomyces coelicolor putative dehydrogenase SCO7101 or SC4B10.02 SWALL:Q9FC85 (EMBL:AL391515) (451 aa) fasta scores: E(): 2.8e-78, 48.95% id in 429 aa, and to Escherichia coli NADH dehydrogenase Ndh or b1109 SWALL:DHNA_ECOLI (SWALL:P00393) (433 aa) fasta scores: E(): 5.9e-20, 31.05% id in 409 aa NP_789712.1 Similar to Mycobacterium tuberculosis hypothetical protein Rv1025 or mt1053 or mtcy10g2.24C SWALL:P96375 (EMBL:Z92539) (163 aa) fasta scores: E(): 1.3e-26, 54.11% id in 146 aa NP_789714.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_789715.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_789716.1 Similar to Escherichia coli sodium/proton antiporter 1 NhaA or Ant or b0019 SWALL:NHAA_ECOLI (SWALL:P13738) (388 aa) fasta scores: E(): 7.6e-35, 35.26% id in 380 aa, and to Streptomyces coelicolor putative sodium/proton antiporter SCO3564 or SCH5.27 SWALL:Q9X929 (EMBL:AL035636) (474 aa) fasta scores: E(): 3.7e-36, 38.24% id in 387 aa NP_789717.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_789718.1 Similar to Bacillus subtilis dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex PdhC or AceC SWALL:ODP2_BACSU (SWALL:P21883) (441 aa) fasta scores: E(): 1.5e-29, 29.53% id in 447 aa, and to Streptomyces coelicolor putative dihydrolipoamide acyltransferase component bkdc1 or sco3815 or scgd3.16C SWALL:Q9XA62 (EMBL:AL096822) (469 aa) fasta scores: E(): 1e-39, 42.07% id in 473 aa NP_789719.1 Similar to Bacillus subtilis pyruvate dehydrogenase E1 component, beta subunit PdhB or AceB SWALL:ODPB_BACSU (SWALL:P21882) (324 aa) fasta scores: E(): 1.1e-43, 41.3% id in 322 aa, and to Streptomyces coelicolor putative branched-chain alpha keto acid dehydrogenase E1 beta subunit BkdB1 or SCO3816 or SCGD3.17C SWALL:Q9XA61 (EMBL:AL096822) (326 aa) fasta scores: E(): 3.1e-68, 57.72% id in 317 aa NP_789720.1 Similar to Bacillus subtilis 2-oxoisovalerate dehydrogenase alpha subunit BfmBaa or BfmB1A SWALL:ODBA_BACSU (SWALL:P37940) (330 aa) fasta scores: E(): 4e-30, 34.13% id in 334 aa, and to Streptomyces coelicolor putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit BkdA1 or SCO3817 or SCGD3.18C SWALL:Q9XA60 (EMBL:AL096822) (417 aa) fasta scores: E(): 4.3e-35, 44.62% id in 363 aa NP_789721.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_789722.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_789723.1 Similar to Rhizobium meliloti putative chorismate mutase protein PheAa or r03241 or smc03858 SWALL:Q92L44 (EMBL:AL591793) (111 aa) fasta scores: E(): 3.2e-05, 33.7% id in 89 aa, and to N-terminal portion of Escherichia coli P-protein [includes: chorismate mutase (cm); prephenate dehydratase (pdt)] PheA or b2599 or z3891 or ecs3462 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 0.18, 31.76% id in 85 aa NP_789724.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_789725.1 Doubtful CDS. No significant database matches NP_789726.1 Similar to Lactococcus lactis phosphoribosylformylglycinamidine synthase I PurQ SWALL:PURQ_LACLC (SWALL:Q9ZB07) (226 aa) fasta scores: E(): 3.5e-32, 44.49% id in 218 aa NP_789727.1 Similar to many CDSs found directly upstream of purQ eg. Streptomyces coelicolor hypothetical protein SCO4077 or SCD25.13 SWALL:Q9RKK7 (EMBL:AL118514) (90 aa) fasta scores: E(): 1.5e-08, 46.34% id in 82 aa NP_789728.1 Similar to many predicted glycosyltransferases eg. Corynebacterium glutamicum predicted glycosyltransferases cgl0401 SWALL:Q8NTA6 (EMBL:AP005275) (418 aa) fasta scores: E(): 2.3e-39, 33.97% id in 415 aa NP_789729.1 N-terminal region similar to many eg. Mycobacterium leprae hypothetical protein Ml1495 SWALL:Q9CBX4 (EMBL:AL583922) (308 aa) fasta scores: E(): 1.9e-13, 33.19% id in 241 aa NP_789730.1 Similar to Bifidobacterium longum NCC2705 conserved hypothetical membrane protein MviN family bl0651 SWALL:AAN24473 (EMBL:AE014686) (575 aa) fasta scores: E(): 5.4e-29, 32.78% id in 482 aa, and to Vibrio cholerae virulence factor MviN homolog or vc0680 SWALL:MVIN_VIBCH (SWALL:O34238) (525 aa) fasta scores: E(): 7.9e-16, 22.96% id in 527 aa NP_789731.1 Similar to Streptomyces coelicolor putative RNA nucleotidyltransferase SCO3896 or SCH24.18 SWALL:Q9X8T2 (EMBL:AL049826) (483 aa) fasta scores: E(): 2.3e-97, 55.35% id in 448 aa, and to Bacillus subtilis poly(a) polymerase PapS SWALL:PAPS_BACSU (SWALL:P42977) (397 aa) fasta scores: E(): 5.5e-20, 39.9% id in 208 aa NP_789732.1 Similar to Streptomyces coelicolor ParB SWALL:Q9RFM2 (EMBL:AF187159) (368 aa) fasta scores: E(): 9.2e-40, 46.38% id in 263 aa NP_789733.1 Similar to Streptomyces coelicolor ParA SWALL:Q9RFM1 (EMBL:AF187159) (357 aa) fasta scores: E(): 2.1e-44, 49.49% id in 295 aa NP_789734.1 Similar to Streptomyces coelicolor probable cation-transporting P-type ATPase SCO2731 or SCC57A.02 SWALL:Q9RDJ4 (EMBL:AL136519) (760 aa) fasta scores: E(): 2.1e-76, 42.31% id in 761 aa, and to Enterococcus hirae probable copper importing ATPase A CopA SWALL:COPA_ENTHR (SWALL:P32113) (727 aa) fasta scores: E(): 1e-65, 36.03% id in 741 aa NP_789735.1 Similar to Streptomyces coelicolor JAG-like protein Jag or SCO3884 or SCH24.06 SWALL:O54595 (EMBL:Y16311) (170 aa) fasta scores: E(): 6.7e-10, 31.13% id in 167 aa NP_789736.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_789737.1 Similar to Streptomyces coelicolor hypothetical protein SCO3882 or SCH24.04 SWALL:Y2I2_STRCO (SWALL:O54625) (124 aa) fasta scores: E(): 1.8e-10, 52.23% id in 67 aa, and to Chlamydia pneumoniae hypothetical protein Cpn0592/Cp0156/Cpj0592 SWALL:Y592_CHLPN (SWALL:Q9Z7W2) (103 aa) fasta scores: E(): 1.3e-09, 34.61% id in 78 aa NP_789738.1 Similar to Bacillus subtilis ribonuclease P protein component RnpA SWALL:RNPA_BACSU (SWALL:P25814) (116 aa) fasta scores: E(): 0.00084, 29.8% id in 104 aa