-- dump date 20111121_015506 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002808789.1 227080238 7774083 complement(235..402) 1 NC_012578.1 hypothetical protein 402 7774083 VCM66_0001 Vibrio cholerae M66-2 hypothetical protein YP_002808789.1 235 R 579112 CDS YP_002808790.1 227080239 7771300 complement(372..806) 1 NC_012578.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 806 mioC 7771300 mioC Vibrio cholerae M66-2 flavodoxin YP_002808790.1 372 R 579112 CDS YP_002808791.1 227080240 7771301 complement(816..2210) 1 NC_012578.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2210 trmE 7771301 trmE Vibrio cholerae M66-2 tRNA modification GTPase TrmE YP_002808791.1 816 R 579112 CDS YP_002808792.1 227080241 7771302 complement(2271..3896) 1 NC_012578.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3896 yidC 7771302 yidC Vibrio cholerae M66-2 putative inner membrane protein translocase component YidC YP_002808792.1 2271 R 579112 CDS YP_002808793.1 227080242 7771303 complement(3899..4156) 1 NC_012578.1 hypothetical protein 4156 7771303 VCM66_0005 Vibrio cholerae M66-2 hypothetical protein YP_002808793.1 3899 R 579112 CDS YP_002808794.1 227080243 7771304 complement(4123..4479) 1 NC_012578.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4479 rnpA 7771304 rnpA Vibrio cholerae M66-2 ribonuclease P YP_002808794.1 4123 R 579112 CDS YP_002808795.1 227080244 7771305 complement(4492..4629) 1 NC_012578.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4629 rpmH 7771305 rpmH Vibrio cholerae M66-2 50S ribosomal protein L34 YP_002808795.1 4492 R 579112 CDS YP_002808796.1 227080245 7771306 complement(4871..5608) 1 NC_012578.1 amino acid ABC transporter ATP-binding protein 5608 7771306 VCM66_0008 Vibrio cholerae M66-2 amino acid ABC transporter ATP-binding protein YP_002808796.1 4871 R 579112 CDS YP_002808797.1 227080246 7771307 complement(5605..6276) 1 NC_012578.1 amino acid ABC transporter permease 6276 7771307 VCM66_0009 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002808797.1 5605 R 579112 CDS YP_002808798.1 227080247 7771308 complement(6354..7100) 1 NC_012578.1 amino acid ABC transporter substrate-binding protein 7100 7771308 VCM66_0010 Vibrio cholerae M66-2 amino acid ABC transporter substrate-binding protein YP_002808798.1 6354 R 579112 CDS YP_002808799.1 227080248 7771309 7224..7352 1 NC_012578.1 hypothetical protein 7352 7771309 VCM66_0011 Vibrio cholerae M66-2 hypothetical protein YP_002808799.1 7224 D 579112 CDS YP_002808800.1 227080249 7771310 7397..8815 1 NC_012578.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 8815 dnaA 7771310 dnaA Vibrio cholerae M66-2 chromosomal replication initiation protein YP_002808800.1 7397 D 579112 CDS YP_002808801.1 227080250 7771311 8873..9973 1 NC_012578.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 9973 dnaN 7771311 dnaN Vibrio cholerae M66-2 DNA polymerase III subunit beta YP_002808801.1 8873 D 579112 CDS YP_002808802.1 227080251 7771312 9991..11082 1 NC_012578.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 11082 recF 7771312 recF Vibrio cholerae M66-2 recombination protein F YP_002808802.1 9991 D 579112 CDS YP_002808803.1 227080252 7771313 11103..13520 1 NC_012578.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 13520 gyrB 7771313 gyrB Vibrio cholerae M66-2 DNA gyrase subunit B YP_002808803.1 11103 D 579112 CDS YP_002808804.1 227080253 7771314 13876..14367 1 NC_012578.1 hypothetical protein 14367 7771314 VCM66_0016 Vibrio cholerae M66-2 hypothetical protein YP_002808804.1 13876 D 579112 CDS YP_002808805.1 227080254 7771315 14377..14493 1 NC_012578.1 hypothetical protein 14493 7771315 VCM66_0017 Vibrio cholerae M66-2 hypothetical protein YP_002808805.1 14377 D 579112 CDS YP_002808806.1 227080255 7771316 14769..15206 1 NC_012578.1 putative heat shock protein 15206 ibpA 7771316 ibpA Vibrio cholerae M66-2 putative heat shock protein YP_002808806.1 14769 D 579112 CDS YP_002808807.1 227080256 7771317 complement(15294..16550) 1 NC_012578.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 16550 avtA 7771317 avtA Vibrio cholerae M66-2 valine--pyruvate transaminase YP_002808807.1 15294 R 579112 CDS YP_002808808.1 227080257 7771318 complement(16869..18935) 1 NC_012578.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 18935 glyS 7771318 glyS Vibrio cholerae M66-2 glycyl-tRNA synthetase subunit beta YP_002808808.1 16869 R 579112 CDS YP_002808809.1 227080258 7771319 complement(18950..19942) 1 NC_012578.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 19942 glyQ 7771319 glyQ Vibrio cholerae M66-2 glycyl-tRNA synthetase subunit alpha YP_002808809.1 18950 R 579112 CDS YP_002808810.1 227080259 7771320 20235..20837 1 NC_012578.1 hypothetical protein 20837 7771320 VCM66_0022 Vibrio cholerae M66-2 hypothetical protein YP_002808810.1 20235 D 579112 CDS YP_002808811.1 227080260 7771321 20943..21200 1 NC_012578.1 NADH dehydrogenase subunit II-like protein 21200 7771321 VCM66_0023 Vibrio cholerae M66-2 NADH dehydrogenase subunit II-like protein YP_002808811.1 20943 D 579112 CDS YP_002808812.1 227080261 7771322 complement(21287..21535) 1 NC_012578.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 21535 7771322 VCM66_0024 Vibrio cholerae M66-2 sulfur transfer protein SirA YP_002808812.1 21287 R 579112 CDS YP_002808813.1 227080262 7771323 21656..21856 1 NC_012578.1 hypothetical protein 21856 7771323 VCM66_0025 Vibrio cholerae M66-2 hypothetical protein YP_002808813.1 21656 D 579112 CDS YP_002808814.1 227080263 7771324 complement(22028..23008) 1 NC_012578.1 zinc-binding alcohol dehydrogenase 23008 7771324 VCM66_0026 Vibrio cholerae M66-2 zinc-binding alcohol dehydrogenase YP_002808814.1 22028 R 579112 CDS YP_002808815.1 227080264 7771325 complement(23256..24788) 1 NC_012578.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 24788 ilvA 7771325 ilvA Vibrio cholerae M66-2 threonine dehydratase YP_002808815.1 23256 R 579112 CDS YP_002808816.1 227080265 7771326 complement(24792..26633) 1 NC_012578.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 26633 ilvD 7771326 ilvD Vibrio cholerae M66-2 dihydroxy-acid dehydratase YP_002808816.1 24792 R 579112 CDS YP_002808817.1 227080266 7771327 complement(26643..27602) 1 NC_012578.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 27602 ilvE 7771327 ilvE Vibrio cholerae M66-2 branched-chain amino acid aminotransferase YP_002808817.1 26643 R 579112 CDS YP_002808818.1 227080267 7771328 complement(27593..27877) 1 NC_012578.1 acetolactate synthase 2 regulatory subunit 27877 ilvM 7771328 ilvM Vibrio cholerae M66-2 acetolactate synthase 2 regulatory subunit YP_002808818.1 27593 R 579112 CDS YP_002808819.1 227080268 7771329 complement(27889..29535) 1 NC_012578.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 29535 ilvG 7771329 ilvG Vibrio cholerae M66-2 acetolactate synthase 2 catalytic subunit YP_002808819.1 27889 R 579112 CDS YP_002808820.1 227080269 7771330 30069..31592 1 NC_012578.1 ComM-like protein 31592 7771330 VCM66_0032 Vibrio cholerae M66-2 ComM-like protein YP_002808820.1 30069 D 579112 CDS YP_002808821.1 227080270 7771331 31682..32566 1 NC_012578.1 putative acyltransferase 32566 7771331 VCM66_0033 Vibrio cholerae M66-2 putative acyltransferase YP_002808821.1 31682 D 579112 CDS YP_002808822.1 227080271 7771332 complement(32643..33245) 1 NC_012578.1 thiol:disulfide interchange protein 33245 tpcG 7771332 tpcG Vibrio cholerae M66-2 thiol:disulfide interchange protein YP_002808822.1 32643 R 579112 CDS YP_002808823.1 227080272 7771333 complement(33276..34298) 1 NC_012578.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 34298 7771333 VCM66_0035 Vibrio cholerae M66-2 serine/threonine protein kinase YP_002808823.1 33276 R 579112 CDS YP_002808824.1 227080273 7771334 complement(34310..35797) 1 NC_012578.1 FixG-like protein 35797 7771334 VCM66_0036 Vibrio cholerae M66-2 FixG-like protein YP_002808824.1 34310 R 579112 CDS YP_002808825.1 227080274 7771335 complement(36151..36429) 1 NC_012578.1 hypothetical protein 36429 7771335 VCM66_0037 Vibrio cholerae M66-2 hypothetical protein YP_002808825.1 36151 R 579112 CDS YP_002808826.1 227080275 7771336 complement(36526..36693) 1 NC_012578.1 hypothetical protein 36693 7771336 VCM66_0038 Vibrio cholerae M66-2 hypothetical protein YP_002808826.1 36526 R 579112 CDS YP_002808827.1 227080276 7771337 36927..37769 1 NC_012578.1 SpoOM-like protein 37769 7771337 VCM66_0039 Vibrio cholerae M66-2 SpoOM-like protein YP_002808827.1 36927 D 579112 CDS YP_002808828.1 227080277 7771338 37847..38494 1 NC_012578.1 putative hemolysin 38494 7771338 VCM66_0040 Vibrio cholerae M66-2 putative hemolysin YP_002808828.1 37847 D 579112 CDS YP_002808829.1 227080278 7771339 complement(38533..39189) 1 NC_012578.1 hypothetical protein 39189 7771339 VCM66_0041 Vibrio cholerae M66-2 hypothetical protein YP_002808829.1 38533 R 579112 CDS YP_002808830.1 227080279 7771340 complement(39102..40547) 1 NC_012578.1 potassium uptake protein TrkH 40547 trkH-1 7771340 trkH-1 Vibrio cholerae M66-2 potassium uptake protein TrkH YP_002808830.1 39102 R 579112 CDS YP_002808831.1 227080280 7771341 complement(40559..41935) 1 NC_012578.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 41935 trkA 7771341 trkA Vibrio cholerae M66-2 potassium transporter peripheral membrane component YP_002808831.1 40559 R 579112 CDS YP_002808832.1 227080281 7771342 complement(41997..43301) 1 NC_012578.1 sun protein 43301 sun 7771342 sun Vibrio cholerae M66-2 sun protein YP_002808832.1 41997 R 579112 CDS YP_002808833.1 227080282 7771343 complement(43333..44280) 1 NC_012578.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 44280 fmt 7771343 fmt Vibrio cholerae M66-2 methionyl-tRNA formyltransferase YP_002808833.1 43333 R 579112 CDS YP_002808834.1 227080283 7771344 complement(44298..44807) 1 NC_012578.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 44807 def 7771344 def Vibrio cholerae M66-2 peptide deformylase YP_002808834.1 44298 R 579112 CDS YP_002808835.1 227080284 7771345 44899..46074 1 NC_012578.1 hypothetical protein 46074 7771345 VCM66_0047 Vibrio cholerae M66-2 hypothetical protein YP_002808835.1 44899 D 579112 CDS YP_002808836.1 227080285 7771346 46074..47189 1 NC_012578.1 smf protein 47189 smf 7771346 smf Vibrio cholerae M66-2 smf protein YP_002808836.1 46074 D 579112 CDS YP_002808837.1 227080286 7771347 47192..47668 1 NC_012578.1 hypothetical protein 47668 smg 7771347 smg Vibrio cholerae M66-2 hypothetical protein YP_002808837.1 47192 D 579112 CDS YP_002808838.1 227080287 7771348 47678..48250 1 NC_012578.1 DNA topoisomerase I-like protein 48250 7771348 VCM66_0050 Vibrio cholerae M66-2 DNA topoisomerase I-like protein YP_002808838.1 47678 D 579112 CDS YP_002808839.1 227080288 7771349 complement(48323..49456) 1 NC_012578.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 49456 purK 7771349 purK Vibrio cholerae M66-2 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002808839.1 48323 R 579112 CDS YP_002808840.1 227080289 7771350 complement(49460..49945) 1 NC_012578.1 phosphoribosylaminoimidazole carboxylase, catalytic subunit 49945 purE 7771350 purE Vibrio cholerae M66-2 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_002808840.1 49460 R 579112 CDS YP_002808841.1 227080290 7771351 49960..50085 1 NC_012578.1 hypothetical protein 50085 7771351 VCM66_0053 Vibrio cholerae M66-2 hypothetical protein YP_002808841.1 49960 D 579112 CDS YP_002808842.1 227080291 7771352 50103..50669 1 NC_012578.1 Sua5/YciO/YrdC family protein 50669 7771352 VCM66_0054 Vibrio cholerae M66-2 Sua5/YciO/YrdC family protein YP_002808842.1 50103 D 579112 CDS YP_002808843.1 227080292 7771353 50688..51605 1 NC_012578.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 51605 hemF 7771353 hemF Vibrio cholerae M66-2 coproporphyrinogen III oxidase YP_002808843.1 50688 D 579112 CDS YP_002808844.1 227080293 7771354 51667..52503 1 NC_012578.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 52503 aroE 7771354 aroE Vibrio cholerae M66-2 shikimate 5-dehydrogenase YP_002808844.1 51667 D 579112 CDS YP_002808845.1 227080294 7771355 52500..52775 1 NC_012578.1 hypothetical protein 52775 7771355 VCM66_0057 Vibrio cholerae M66-2 hypothetical protein YP_002808845.1 52500 D 579112 CDS YP_002808846.1 227080295 7771356 complement(52756..53310) 1 NC_012578.1 carbonic anhydrase, family 3 53310 7771356 VCM66_0058 Vibrio cholerae M66-2 carbonic anhydrase, family 3 YP_002808846.1 52756 R 579112 CDS YP_002808847.1 227080296 7774073 59321..59701 1 NC_012578.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 59701 crcB 7774073 crcB Vibrio cholerae M66-2 camphor resistance protein CrcB YP_002808847.1 59321 D 579112 CDS YP_002808848.1 227080297 7771358 59953..61890 1 NC_012578.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 61890 thiC 7771358 thiC Vibrio cholerae M66-2 thiamine biosynthesis protein ThiC YP_002808848.1 59953 D 579112 CDS YP_002808849.1 227080298 7771359 61894..63216 1 NC_012578.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 63216 thiE 7771359 thiE Vibrio cholerae M66-2 thiamine-phosphate pyrophosphorylase YP_002808849.1 61894 D 579112 CDS YP_002808850.1 227080299 7771360 63203..63979 1 NC_012578.1 thiF protein 63979 thiF 7771360 thiF Vibrio cholerae M66-2 thiF protein YP_002808850.1 63203 D 579112 CDS YP_002808851.1 227080300 7771361 63922..64179 1 NC_012578.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 64179 thiS 7771361 thiS Vibrio cholerae M66-2 sulfur carrier protein ThiS YP_002808851.1 63922 D 579112 CDS YP_002808852.1 227080301 7771362 64185..64955 1 NC_012578.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 64955 thiG 7771362 thiG Vibrio cholerae M66-2 thiazole synthase YP_002808852.1 64185 D 579112 CDS YP_002808853.1 227080302 7771363 64952..66064 1 NC_012578.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 66064 thiH 7771363 thiH Vibrio cholerae M66-2 thiamine biosynthesis protein ThiH YP_002808853.1 64952 D 579112 CDS YP_002808854.1 227080303 7771364 complement(66289..68082) 1 NC_012578.1 aminopeptidase P 68082 7771364 VCM66_0067 Vibrio cholerae M66-2 aminopeptidase P YP_002808854.1 66289 R 579112 CDS YP_002808855.1 227080304 7771365 complement(68215..69198) 1 NC_012578.1 LysR family transcriptional regulator 69198 7771365 VCM66_0068 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002808855.1 68215 R 579112 CDS YP_002808856.1 227080305 7771366 69261..70463 1 NC_012578.1 putative multidrug resistance protein 70463 7771366 VCM66_0069 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002808856.1 69261 D 579112 CDS YP_002808857.1 227080306 7771367 70567..70851 1 NC_012578.1 hypothetical protein 70851 7771367 VCM66_0070 Vibrio cholerae M66-2 hypothetical protein YP_002808857.1 70567 D 579112 CDS YP_002808858.1 227080307 7771368 complement(70940..71401) 1 NC_012578.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 71401 asnC 7771368 asnC Vibrio cholerae M66-2 DNA-binding transcriptional regulator AsnC YP_002808858.1 70940 R 579112 CDS YP_002808859.1 227080308 7771369 71477..73783 1 NC_012578.1 GGDEF/EAL family protein 73783 7771369 VCM66_0072 Vibrio cholerae M66-2 GGDEF/EAL family protein YP_002808859.1 71477 D 579112 CDS YP_002808860.1 227080309 7771370 73750..74628 1 NC_012578.1 hypothetical protein 74628 7771370 VCM66_0073 Vibrio cholerae M66-2 hypothetical protein YP_002808860.1 73750 D 579112 CDS YP_002808861.1 227080310 7771371 74746..75135 1 NC_012578.1 hypothetical protein 75135 7771371 VCM66_0074 Vibrio cholerae M66-2 hypothetical protein YP_002808861.1 74746 D 579112 CDS YP_002808862.1 227080311 7771372 complement(75231..76118) 1 NC_012578.1 MadN protein 76118 madN 7771372 madN Vibrio cholerae M66-2 MadN protein YP_002808862.1 75231 R 579112 CDS YP_002808863.1 227080312 7771373 complement(76175..76600) 1 NC_012578.1 universal stress protein A 76600 uspA 7771373 uspA Vibrio cholerae M66-2 universal stress protein A YP_002808863.1 76175 R 579112 CDS YP_002808864.1 227080313 7771374 76646..76741 1 NC_012578.1 hypothetical protein 76741 7771374 VCM66_0077 Vibrio cholerae M66-2 hypothetical protein YP_002808864.1 76646 D 579112 CDS YP_002808865.1 227080314 7771375 76747..77292 1 NC_012578.1 ferritin 77292 ftn 7771375 ftn Vibrio cholerae M66-2 ferritin YP_002808865.1 76747 D 579112 CDS YP_002808866.1 227080315 7771376 77368..77691 1 NC_012578.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 77691 7771376 VCM66_0079 Vibrio cholerae M66-2 universal stress protein UspB YP_002808866.1 77368 D 579112 CDS YP_002808867.1 227080316 7771377 77824..79020 1 NC_012578.1 hypothetical protein 79020 7771377 VCM66_0080 Vibrio cholerae M66-2 hypothetical protein YP_002808867.1 77824 D 579112 CDS YP_002808868.1 227080317 7771378 complement(79017..79928) 1 NC_012578.1 hypothetical protein 79928 7771378 VCM66_0081 Vibrio cholerae M66-2 hypothetical protein YP_002808868.1 79017 R 579112 CDS YP_002808869.1 227080318 7771379 80042..81583 1 NC_012578.1 putative DNA recombination protein rmuC 81583 7771379 VCM66_0082 Vibrio cholerae M66-2 putative DNA recombination protein rmuC YP_002808869.1 80042 D 579112 CDS YP_002808870.1 227080319 7771380 81628..82410 1 NC_012578.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 82410 ubiE 7771380 ubiE Vibrio cholerae M66-2 ubiquinone/menaquinone biosynthesis methyltransferase YP_002808870.1 81628 D 579112 CDS YP_002808871.1 227080320 7771381 82419..83042 1 NC_012578.1 hypothetical protein 83042 7771381 VCM66_0084 Vibrio cholerae M66-2 hypothetical protein YP_002808871.1 82419 D 579112 CDS YP_002808872.1 227080321 7771382 83039..84673 1 NC_012578.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 84673 ubiB 7771382 ubiB Vibrio cholerae M66-2 putative ubiquinone biosynthesis protein UbiB YP_002808872.1 83039 D 579112 CDS YP_002808873.1 227080322 7771383 84733..84981 1 NC_012578.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 84981 tatA 7771383 tatA Vibrio cholerae M66-2 twin arginine translocase protein A YP_002808873.1 84733 D 579112 CDS YP_002808874.1 227080323 7771384 84985..85386 1 NC_012578.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 85386 7771384 VCM66_0087 Vibrio cholerae M66-2 sec-independent translocase YP_002808874.1 84985 D 579112 CDS YP_002808875.1 227080324 7771385 85475..86227 1 NC_012578.1 Sec-independent protein translocase protein tatC 86227 7771385 VCM66_0088 Vibrio cholerae M66-2 Sec-independent protein translocase protein tatC YP_002808875.1 85475 D 579112 CDS YP_002808876.1 227080325 7771386 86539..87540 1 NC_012578.1 cytochrome c551 peroxidase 87540 yhjA 7771386 yhjA Vibrio cholerae M66-2 cytochrome c551 peroxidase YP_002808876.1 86539 D 579112 CDS YP_002808877.1 227080326 7771387 complement(87646..89010) 1 NC_012578.1 DNA-damage-inducible protein F 89010 dinF 7771387 dinF Vibrio cholerae M66-2 DNA-damage-inducible protein F YP_002808877.1 87646 R 579112 CDS YP_002808878.1 227080327 7771388 complement(89081..89950) 1 NC_012578.1 O-methyltransferase-like protein 89950 7771388 VCM66_0091 Vibrio cholerae M66-2 O-methyltransferase-like protein YP_002808878.1 89081 R 579112 CDS YP_002808879.1 227080328 7771389 complement(89978..90607) 1 NC_012578.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 90607 lexA 7771389 lexA Vibrio cholerae M66-2 LexA repressor YP_002808879.1 89978 R 579112 CDS YP_002808880.1 227080329 7771390 90918..93353 1 NC_012578.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 93353 plsB 7771390 plsB Vibrio cholerae M66-2 glycerol-3-phosphate acyltransferase YP_002808880.1 90918 D 579112 CDS YP_002808881.1 227080330 7771391 complement(93429..94283) 1 NC_012578.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 94283 ubiA 7771391 ubiA Vibrio cholerae M66-2 4-hydroxybenzoate octaprenyltransferase YP_002808881.1 93429 R 579112 CDS YP_002808882.1 227080331 7771392 complement(94284..94835) 1 NC_012578.1 chorismate-pyruvate lyase 94835 ubiC 7771392 ubiC Vibrio cholerae M66-2 chorismate-pyruvate lyase YP_002808882.1 94284 R 579112 CDS YP_002808883.1 227080332 7771393 complement(94858..94956) 1 NC_012578.1 hypothetical protein 94956 7771393 VCM66_0096 Vibrio cholerae M66-2 hypothetical protein YP_002808883.1 94858 R 579112 CDS YP_002808884.1 227080333 7771394 95027..95437 1 NC_012578.1 flagellar basal body-associated protein FliL-like protein 95437 7771394 VCM66_0097 Vibrio cholerae M66-2 flagellar basal body-associated protein FliL-like protein YP_002808884.1 95027 D 579112 CDS YP_002808885.1 227080334 7771395 complement(95557..97536) 1 NC_012578.1 methyl-accepting chemotaxis protein 97536 7771395 VCM66_0098 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002808885.1 95557 R 579112 CDS YP_002808886.1 227080335 7771396 complement(97911..98744) 1 NC_012578.1 glpG protein 98744 glpG 7771396 glpG Vibrio cholerae M66-2 glpG protein YP_002808886.1 97911 R 579112 CDS YP_002808887.1 227080336 7771397 complement(98751..99071) 1 NC_012578.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 99071 glpE 7771397 glpE Vibrio cholerae M66-2 thiosulfate sulfurtransferase YP_002808887.1 98751 R 579112 CDS YP_002808888.1 227080337 7771398 complement(99152..99367) 1 NC_012578.1 hypothetical protein 99367 7771398 VCM66_0101 Vibrio cholerae M66-2 hypothetical protein YP_002808888.1 99152 R 579112 CDS YP_002808889.1 227080338 7771399 complement(99600..99740) 1 NC_012578.1 hypothetical protein 99740 7771399 VCM66_0102 Vibrio cholerae M66-2 hypothetical protein YP_002808889.1 99600 R 579112 CDS YP_002808890.1 227080339 7771400 complement(99832..100599) 1 NC_012578.1 Putative deoxyribonuclease yabD 100599 7771400 VCM66_0103 Vibrio cholerae M66-2 Putative deoxyribonuclease yabD YP_002808890.1 99832 R 579112 CDS YP_002808891.1 227080340 7771401 complement(100655..100789) 1 NC_012578.1 hypothetical protein 100789 7771401 VCM66_0104 Vibrio cholerae M66-2 hypothetical protein YP_002808891.1 100655 R 579112 CDS YP_002808892.1 227080341 7771402 100776..101819 1 NC_012578.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 101819 hemB 7771402 hemB Vibrio cholerae M66-2 delta-aminolevulinic acid dehydratase YP_002808892.1 100776 D 579112 CDS YP_002808893.1 227080342 7771403 101923..102354 1 NC_012578.1 hypothetical protein 102354 7771403 VCM66_0106 Vibrio cholerae M66-2 hypothetical protein YP_002808893.1 101923 D 579112 CDS YP_002808894.1 227080343 7771404 complement(102873..103010) 1 NC_012578.1 hypothetical protein 103010 7771404 VCM66_0107 Vibrio cholerae M66-2 hypothetical protein YP_002808894.1 102873 R 579112 CDS YP_002808895.1 227080344 7771405 103063..105867 1 NC_012578.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 105867 polI 7771405 polI Vibrio cholerae M66-2 DNA polymerase I YP_002808895.1 103063 D 579112 CDS YP_002808896.1 227080345 7771406 complement(105820..105933) 1 NC_012578.1 hypothetical protein 105933 7771406 VCM66_0109 Vibrio cholerae M66-2 hypothetical protein YP_002808896.1 105820 R 579112 CDS YP_002808897.1 227080346 7771407 106130..106264 1 NC_012578.1 hypothetical protein 106264 7771407 VCM66_0110 Vibrio cholerae M66-2 hypothetical protein YP_002808897.1 106130 D 579112 CDS YP_002808898.1 227080347 7771408 complement(106614..107276) 1 NC_012578.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 107276 engB 7771408 engB Vibrio cholerae M66-2 ribosome biogenesis GTP-binding protein YsxC YP_002808898.1 106614 R 579112 CDS YP_002808899.1 227080348 7771409 107374..108045 1 NC_012578.1 cytochrome c4 108045 cycA 7771409 cycA Vibrio cholerae M66-2 cytochrome c4 YP_002808899.1 107374 D 579112 CDS YP_002808900.1 227080349 7771410 108217..108885 1 NC_012578.1 methyltransferase-like protein 108885 7771410 VCM66_0113 Vibrio cholerae M66-2 methyltransferase-like protein YP_002808900.1 108217 D 579112 CDS YP_002808901.1 227080350 7771411 108885..109433 1 NC_012578.1 hypothetical protein 109433 7771411 VCM66_0114 Vibrio cholerae M66-2 hypothetical protein YP_002808901.1 108885 D 579112 CDS YP_002808902.1 227080351 7771412 109440..109931 1 NC_012578.1 hypothetical protein 109931 7771412 VCM66_0115 Vibrio cholerae M66-2 hypothetical protein YP_002808902.1 109440 D 579112 CDS YP_002808903.1 227080352 7771413 110016..111458 1 NC_012578.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 111458 hemN 7771413 hemN Vibrio cholerae M66-2 coproporphyrinogen III oxidase YP_002808903.1 110016 D 579112 CDS YP_002808904.1 227080353 7771414 complement(111522..112718) 1 NC_012578.1 hemY protein 112718 hemY 7771414 hemY Vibrio cholerae M66-2 hemY protein YP_002808904.1 111522 R 579112 CDS YP_002808905.1 227080354 7771415 complement(112715..113914) 1 NC_012578.1 putative uroporphyrin-III C-methyltransferase 113914 7771415 VCM66_0118 Vibrio cholerae M66-2 putative uroporphyrin-III C-methyltransferase YP_002808905.1 112715 R 579112 CDS YP_002808906.1 227080355 7771416 complement(113898..114680) 1 NC_012578.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 114680 hemD 7771416 hemD Vibrio cholerae M66-2 uroporphyrinogen-III synthase YP_002808906.1 113898 R 579112 CDS YP_002808907.1 227080356 7771417 complement(114726..115679) 1 NC_012578.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 115679 hemC 7771417 hemC Vibrio cholerae M66-2 porphobilinogen deaminase YP_002808907.1 114726 R 579112 CDS YP_002808908.1 227080357 7771418 complement(115856..116002) 1 NC_012578.1 hypothetical protein 116002 7771418 VCM66_0121 Vibrio cholerae M66-2 hypothetical protein YP_002808908.1 115856 R 579112 CDS YP_002808909.1 227080358 7771419 116018..118549 1 NC_012578.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 118549 cyaA 7771419 cyaA Vibrio cholerae M66-2 adenylate cyclase YP_002808909.1 116018 D 579112 CDS YP_002808910.1 227080359 7771420 complement(118655..118969) 1 NC_012578.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 118969 cyaY 7771420 cyaY Vibrio cholerae M66-2 frataxin-like protein YP_002808910.1 118655 R 579112 CDS YP_002808911.1 227080360 7771421 118946..119161 1 NC_012578.1 hypothetical protein 119161 lppL 7771421 lppL Vibrio cholerae M66-2 hypothetical protein YP_002808911.1 118946 D 579112 CDS YP_002808912.1 227080361 7771422 119194..120447 1 NC_012578.1 diaminopimelate decarboxylase 120447 lysA 7771422 lysA Vibrio cholerae M66-2 diaminopimelate decarboxylase YP_002808912.1 119194 D 579112 CDS YP_002808913.1 227080362 7771423 120417..121289 1 NC_012578.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 121289 dapF 7771423 dapF Vibrio cholerae M66-2 diaminopimelate epimerase YP_002808913.1 120417 D 579112 CDS YP_002808914.1 227080363 7771424 121303..122001 1 NC_012578.1 hypothetical protein 122001 7771424 VCM66_0127 Vibrio cholerae M66-2 hypothetical protein YP_002808914.1 121303 D 579112 CDS YP_002808915.1 227080364 7771425 121970..122905 1 NC_012578.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 122905 xerC 7771425 xerC Vibrio cholerae M66-2 site-specific tyrosine recombinase XerC YP_002808915.1 121970 D 579112 CDS YP_002808916.1 227080365 7771426 122908..123627 1 NC_012578.1 hypothetical protein 123627 7771426 VCM66_0129 Vibrio cholerae M66-2 hypothetical protein YP_002808916.1 122908 D 579112 CDS YP_002808917.1 227080366 7771427 123737..126226 1 NC_012578.1 GGDEF/EAL family protein 126226 7771427 VCM66_0130 Vibrio cholerae M66-2 GGDEF/EAL family protein YP_002808917.1 123737 D 579112 CDS YP_002808918.1 227080367 7771428 complement(126259..126855) 1 NC_012578.1 hypothetical protein 126855 7771428 VCM66_0131 Vibrio cholerae M66-2 hypothetical protein YP_002808918.1 126259 R 579112 CDS YP_002808919.1 227080368 7771429 complement(126852..128396) 1 NC_012578.1 hypothetical protein 128396 7771429 VCM66_0132 Vibrio cholerae M66-2 hypothetical protein YP_002808919.1 126852 R 579112 CDS YP_002808920.1 227080369 7771430 128409..128597 1 NC_012578.1 hypothetical protein 128597 7771430 VCM66_0133 Vibrio cholerae M66-2 hypothetical protein YP_002808920.1 128409 D 579112 CDS YP_002808921.1 227080370 7771431 complement(128680..129507) 1 NC_012578.1 hypothetical protein 129507 7771431 VCM66_0134 Vibrio cholerae M66-2 hypothetical protein YP_002808921.1 128680 R 579112 CDS YP_002808922.1 227080371 7771432 complement(129622..130638) 1 NC_012578.1 lysophospholipase L2 130638 lypA 7771432 lypA Vibrio cholerae M66-2 lysophospholipase L2 YP_002808922.1 129622 R 579112 CDS YP_002808923.1 227080372 7771433 130713..131330 1 NC_012578.1 homoserine/homoserine lactone efflux protein 131330 rhtB 7771433 rhtB Vibrio cholerae M66-2 homoserine/homoserine lactone efflux protein YP_002808923.1 130713 D 579112 CDS YP_002808924.1 227080373 7771434 131278..132576 1 NC_012578.1 HD-GYP/EAL family protein 132576 7771434 VCM66_0137 Vibrio cholerae M66-2 HD-GYP/EAL family protein YP_002808924.1 131278 D 579112 CDS YP_002808925.1 227080374 7771435 complement(132584..132703) 1 NC_012578.1 hypothetical protein 132703 7771435 VCM66_0138 Vibrio cholerae M66-2 hypothetical protein YP_002808925.1 132584 R 579112 CDS YP_002808926.1 227080375 7771436 complement(132756..133226) 1 NC_012578.1 DPS family protein 133226 7771436 VCM66_0139 Vibrio cholerae M66-2 DPS family protein YP_002808926.1 132756 R 579112 CDS YP_002808927.1 227080376 7771437 complement(133396..133725) 1 NC_012578.1 hypothetical protein 133725 7771437 VCM66_0140 Vibrio cholerae M66-2 hypothetical protein YP_002808927.1 133396 R 579112 CDS YP_002808928.1 227080377 7771438 133764..133868 1 NC_012578.1 hypothetical protein 133868 7771438 VCM66_0141 Vibrio cholerae M66-2 hypothetical protein YP_002808928.1 133764 D 579112 CDS YP_002808929.1 227080378 7771439 133930..134298 1 NC_012578.1 hypothetical protein 134298 7771439 VCM66_0142 Vibrio cholerae M66-2 hypothetical protein YP_002808929.1 133930 D 579112 CDS YP_002808930.1 227080379 7771440 135175..135804 1 NC_012578.1 hypothetical protein 135804 7771440 VCM66_0144 Vibrio cholerae M66-2 hypothetical protein YP_002808930.1 135175 D 579112 CDS YP_002808931.1 227080380 7771441 complement(135853..136119) 1 NC_012578.1 hypothetical protein 136119 7771441 VCM66_0145 Vibrio cholerae M66-2 hypothetical protein YP_002808931.1 135853 R 579112 CDS YP_002808932.1 227080381 7771442 complement(136116..136715) 1 NC_012578.1 Putative methylase 136715 7771442 VCM66_0146 Vibrio cholerae M66-2 Putative methylase YP_002808932.1 136116 R 579112 CDS YP_002808933.1 227080382 7771443 136919..138100 1 NC_012578.1 cell division protein FtsY 138100 ftsY 7771443 ftsY Vibrio cholerae M66-2 cell division protein FtsY YP_002808933.1 136919 D 579112 CDS YP_002808934.1 227080383 7771444 138122..138823 1 NC_012578.1 cell division ATP-binding protein FtsE 138823 ftsE 7771444 ftsE Vibrio cholerae M66-2 cell division ATP-binding protein FtsE YP_002808934.1 138122 D 579112 CDS YP_002808935.1 227080384 7771445 138813..139805 1 NC_012578.1 cell division protein FtsX 139805 ftsX 7771445 ftsX Vibrio cholerae M66-2 cell division protein FtsX YP_002808935.1 138813 D 579112 CDS YP_002808936.1 227080385 7771446 139975..140835 1 NC_012578.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 140835 rpoH 7771446 rpoH Vibrio cholerae M66-2 RNA polymerase factor sigma-32 YP_002808936.1 139975 D 579112 CDS YP_002808937.1 227080386 7771447 complement(141037..142437) 1 NC_012578.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 142437 dude 7771447 dude Vibrio cholerae M66-2 soluble pyridine nucleotide transhydrogenase YP_002808937.1 141037 R 579112 CDS YP_002808938.1 227080387 7771448 142745..143386 1 NC_012578.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 143386 7771448 VCM66_0152 Vibrio cholerae M66-2 DNA-binding transcriptional repressor FabR YP_002808938.1 142745 D 579112 CDS YP_002808939.1 227080388 7771449 143426..143797 1 NC_012578.1 hypothetical protein 143797 7771449 VCM66_0153 Vibrio cholerae M66-2 hypothetical protein YP_002808939.1 143426 D 579112 CDS YP_002808940.1 227080389 7771450 complement(143834..144943) 1 NC_012578.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 144943 trmA 7771450 trmA Vibrio cholerae M66-2 tRNA (uracil-5-)-methyltransferase YP_002808940.1 143834 R 579112 CDS YP_002808941.1 227080390 7771451 145341..147176 1 NC_012578.1 vitamin B12 receptor 147176 btuB 7771451 btuB Vibrio cholerae M66-2 vitamin B12 receptor YP_002808941.1 145341 D 579112 CDS YP_002808942.1 227080391 7771452 complement(147249..148856) 1 NC_012578.1 alkaline serine protease 148856 7771452 VCM66_0156 Vibrio cholerae M66-2 alkaline serine protease YP_002808942.1 147249 R 579112 CDS YP_002808943.1 227080392 7771453 149249..150046 1 NC_012578.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 150046 murI 7771453 murI Vibrio cholerae M66-2 glutamate racemase YP_002808943.1 149249 D 579112 CDS YP_002808944.1 227080393 7771454 complement(150012..150470) 1 NC_012578.1 RNA-binding protein 150470 7771454 VCM66_0158 Vibrio cholerae M66-2 RNA-binding protein YP_002808944.1 150012 R 579112 CDS YP_002808945.1 227080394 7774062 complement(156659..157555) 1 NC_012578.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 157555 ilvY 7774062 ilvY Vibrio cholerae M66-2 DNA-binding transcriptional regulator IlvY YP_002808945.1 156659 R 579112 CDS YP_002808946.1 227080395 7771456 157693..159177 1 NC_012578.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 159177 ilvC 7771456 ilvC Vibrio cholerae M66-2 ketol-acid reductoisomerase YP_002808946.1 157693 D 579112 CDS YP_002808947.1 227080396 7771457 complement(159304..159555) 1 NC_012578.1 hypothetical protein 159555 7771457 VCM66_0162 Vibrio cholerae M66-2 hypothetical protein YP_002808947.1 159304 R 579112 CDS YP_002808948.1 227080397 7771458 complement(159671..162781) 1 NC_012578.1 putative multidrug resistance protein 162781 7771458 VCM66_0163 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002808948.1 159671 R 579112 CDS YP_002808949.1 227080398 7771459 complement(162793..163899) 1 NC_012578.1 hypothetical protein 163899 7771459 VCM66_0164 Vibrio cholerae M66-2 hypothetical protein YP_002808949.1 162793 R 579112 CDS YP_002808950.1 227080399 7771460 complement(163918..164514) 1 NC_012578.1 TetR family transcriptional regulator 164514 7771460 VCM66_0165 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002808950.1 163918 R 579112 CDS YP_002808951.1 227080400 7771461 164660..166675 1 NC_012578.1 ATP-dependent DNA helicase Rep 166675 rep 7771461 rep Vibrio cholerae M66-2 ATP-dependent DNA helicase Rep YP_002808951.1 164660 D 579112 CDS YP_002808952.1 227080401 7771462 complement(166742..167149) 1 NC_012578.1 cytochrome c5 167149 cycB 7771462 cycB Vibrio cholerae M66-2 cytochrome c5 YP_002808952.1 166742 R 579112 CDS YP_002808953.1 227080402 7774059 complement(168484..168651) 1 NC_012578.1 hypothetical protein 168651 7774059 VCM66_0168 Vibrio cholerae M66-2 hypothetical protein YP_002808953.1 168484 R 579112 CDS YP_002808954.1 227080403 7771464 168784..170499 1 NC_012578.1 peptide ABC transporter ATP-binding protein 170499 7771464 VCM66_0169 Vibrio cholerae M66-2 peptide ABC transporter ATP-binding protein YP_002808954.1 168784 D 579112 CDS YP_002808955.1 227080404 7771465 170519..172147 1 NC_012578.1 peptide ABC transporter substrate-binding protein 172147 7771465 VCM66_0170 Vibrio cholerae M66-2 peptide ABC transporter substrate-binding protein YP_002808955.1 170519 D 579112 CDS YP_002808956.1 227080405 7771466 172251..173279 1 NC_012578.1 peptide ABC transporter permease 173279 7771466 VCM66_0171 Vibrio cholerae M66-2 peptide ABC transporter permease YP_002808956.1 172251 D 579112 CDS YP_002808957.1 227080406 7771467 173282..174220 1 NC_012578.1 peptide ABC transporter permease 174220 7771467 VCM66_0172 Vibrio cholerae M66-2 peptide ABC transporter permease YP_002808957.1 173282 D 579112 CDS YP_002808958.1 227080407 7771468 174395..175342 1 NC_012578.1 hypothetical protein 175342 7771468 VCM66_0173 Vibrio cholerae M66-2 hypothetical protein YP_002808958.1 174395 D 579112 CDS YP_002808959.1 227080408 7771469 complement(175437..176804) 1 NC_012578.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 176804 gor 7771469 gor Vibrio cholerae M66-2 glutathione reductase YP_002808959.1 175437 R 579112 CDS YP_002808960.1 227080409 7771470 complement(176898..177737) 1 NC_012578.1 hypothetical protein 177737 7771470 VCM66_0175 Vibrio cholerae M66-2 hypothetical protein YP_002808960.1 176898 R 579112 CDS YP_002808961.1 227080410 7771471 178017..180059 1 NC_012578.1 oligopeptidase A 180059 prlC 7771471 prlC Vibrio cholerae M66-2 oligopeptidase A YP_002808961.1 178017 D 579112 CDS YP_002808962.1 227080411 7771472 180084..180182 1 NC_012578.1 hypothetical protein 180182 7771472 VCM66_0177 Vibrio cholerae M66-2 hypothetical protein YP_002808962.1 180084 D 579112 CDS YP_002808963.1 227080412 7771473 180197..182368 1 NC_012578.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 182368 uvrD 7771473 uvrD Vibrio cholerae M66-2 DNA-dependent helicase II YP_002808963.1 180197 D 579112 CDS YP_002808964.1 227080413 7771474 complement(183114..183782) 1 NC_012578.1 Threonine efflux protein 183782 7771474 VCM66_0179 Vibrio cholerae M66-2 Threonine efflux protein YP_002808964.1 183114 R 579112 CDS YP_002808965.1 227080414 7771475 complement(183857..184669) 1 NC_012578.1 AraC family transcriptional regulator 184669 7771475 VCM66_0180 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002808965.1 183857 R 579112 CDS YP_002808966.1 227080415 7771476 complement(184706..184801) 1 NC_012578.1 hypothetical protein 184801 7771476 VCM66_0181 Vibrio cholerae M66-2 hypothetical protein YP_002808966.1 184706 R 579112 CDS YP_002808967.1 227080416 7773949 complement(186753..187661) 1 NC_012578.1 rarD protein 187661 rarD 7773949 rarD Vibrio cholerae M66-2 rarD protein YP_002808967.1 186753 R 579112 CDS YP_002808968.1 227080417 7771478 187795..189657 1 NC_012578.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 189657 recQ 7771478 recQ Vibrio cholerae M66-2 ATP-dependent DNA helicase RecQ YP_002808968.1 187795 D 579112 CDS YP_002808969.1 227080418 7771479 189650..189949 1 NC_012578.1 gene 3 protein-like protein 189949 7771479 VCM66_0185 Vibrio cholerae M66-2 gene 3 protein-like protein YP_002808969.1 189650 D 579112 CDS YP_002808970.1 227080419 7771480 190105..190482 1 NC_012578.1 hypothetical protein 190482 7771480 VCM66_0186 Vibrio cholerae M66-2 hypothetical protein YP_002808970.1 190105 D 579112 CDS YP_002808971.1 227080420 7771481 complement(190518..192353) 1 NC_012578.1 putative hemolysin secretion ATP-binding protein 192353 7771481 VCM66_0187 Vibrio cholerae M66-2 putative hemolysin secretion ATP-binding protein YP_002808971.1 190518 R 579112 CDS YP_002808972.1 227080421 7771482 192425..194581 1 NC_012578.1 iron(III) compound receptor 194581 fhuA 7771482 fhuA Vibrio cholerae M66-2 iron(III) compound receptor YP_002808972.1 192425 D 579112 CDS YP_002808973.1 227080422 7771483 194640..195497 1 NC_012578.1 iron(III) ABC transporter ATP-binding protein 195497 fhuB 7771483 fhuB Vibrio cholerae M66-2 iron(III) ABC transporter ATP-binding protein YP_002808973.1 194640 D 579112 CDS YP_002808974.1 227080423 7771484 195488..196447 1 NC_012578.1 iron(III) ABC transporter periplasmic iron-compound-binding protein 196447 fhuC 7771484 fhuC Vibrio cholerae M66-2 iron(III) ABC transporter periplasmic iron-compound-binding protein YP_002808974.1 195488 D 579112 CDS YP_002808975.1 227080424 7771485 196444..198405 1 NC_012578.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 198405 fhuD 7771485 fhuD Vibrio cholerae M66-2 iron-hydroxamate transporter permease subunit YP_002808975.1 196444 D 579112 CDS YP_002808976.1 227080425 7771486 complement(198432..199280) 1 NC_012578.1 Putative HTH-type transcriptional regulator yfeT 199280 7771486 VCM66_0192 Vibrio cholerae M66-2 Putative HTH-type transcriptional regulator yfeT YP_002808976.1 198432 R 579112 CDS YP_002808977.1 227080426 7771487 199323..199514 1 NC_012578.1 hypothetical protein 199514 7771487 VCM66_0193 Vibrio cholerae M66-2 hypothetical protein YP_002808977.1 199323 D 579112 CDS YP_002808978.1 227080427 7771488 199496..200413 1 NC_012578.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 200413 murQ 7771488 murQ Vibrio cholerae M66-2 N-acetylmuramic acid-6-phosphate etherase YP_002808978.1 199496 D 579112 CDS YP_002808979.1 227080428 7771489 200434..201882 1 NC_012578.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 201882 murP 7771489 murP Vibrio cholerae M66-2 PTS system N-acetylmuramic acid transporter subunits EIIBC YP_002808979.1 200434 D 579112 CDS YP_002808980.1 227080429 7771490 complement(201989..202477) 1 NC_012578.1 hypothetical protein 202477 7771490 VCM66_0196 Vibrio cholerae M66-2 hypothetical protein YP_002808980.1 201989 R 579112 CDS YP_002808981.1 227080430 7771491 complement(202543..203409) 1 NC_012578.1 hypothetical protein 203409 7771491 VCM66_0197 Vibrio cholerae M66-2 hypothetical protein YP_002808981.1 202543 R 579112 CDS YP_002808982.1 227080431 7771492 203516..204289 1 NC_012578.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 204289 rph 7771492 rph Vibrio cholerae M66-2 ribonuclease PH YP_002808982.1 203516 D 579112 CDS YP_002808983.1 227080432 7771493 204652..205296 1 NC_012578.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 205296 pyrE 7771493 pyrE Vibrio cholerae M66-2 orotate phosphoribosyltransferase YP_002808983.1 204652 D 579112 CDS YP_002808984.1 227080433 7773950 complement(206375..207331) 1 NC_012578.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 207331 htrB 7773950 htrB Vibrio cholerae M66-2 lipid A biosynthesis lauroyl acyltransferase YP_002808984.1 206375 R 579112 CDS YP_002808985.1 227080434 7771495 complement(207328..207960) 1 NC_012578.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 207960 slmA 7771495 slmA Vibrio cholerae M66-2 nucleoid occlusion protein YP_002808985.1 207328 R 579112 CDS YP_002808986.1 227080435 7771496 complement(208077..209276) 1 NC_012578.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 209276 dfp 7771496 dfp Vibrio cholerae M66-2 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002808986.1 208077 R 579112 CDS YP_002808987.1 227080436 7771497 209444..211138 1 NC_012578.1 methyl-accepting chemotaxis protein 211138 7771497 VCM66_0204 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002808987.1 209444 D 579112 CDS YP_002808988.1 227080437 7771498 211250..211924 1 NC_012578.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 211924 radC 7771498 radC Vibrio cholerae M66-2 DNA repair protein RadC YP_002808988.1 211250 D 579112 CDS YP_002808989.1 227080438 7771499 212219..212455 1 NC_012578.1 required for 70S ribosome assembly; 50S ribosomal protein L28 212455 rpmB 7771499 rpmB Vibrio cholerae M66-2 50S ribosomal protein L28 YP_002808989.1 212219 D 579112 CDS YP_002808990.1 227080439 7771500 212469..212636 1 NC_012578.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 212636 rpmG 7771500 rpmG Vibrio cholerae M66-2 50S ribosomal protein L33 YP_002808990.1 212469 D 579112 CDS YP_002808991.1 227080440 7771501 212857..213345 1 NC_012578.1 hypothetical protein 213345 7771501 VCM66_0208 Vibrio cholerae M66-2 hypothetical protein YP_002808991.1 212857 D 579112 CDS YP_002808992.1 227080441 7771502 213355..214164 1 NC_012578.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 214164 mutM 7771502 mutM Vibrio cholerae M66-2 formamidopyrimidine-DNA glycosylase YP_002808992.1 213355 D 579112 CDS YP_002808993.1 227080442 7771503 complement(214261..214755) 1 NC_012578.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 214755 coaD 7771503 coaD Vibrio cholerae M66-2 phosphopantetheine adenylyltransferase YP_002808993.1 214261 R 579112 CDS YP_002808994.1 227080443 7771504 214866..215903 1 NC_012578.1 putative ADP-heptose--LPS heptosyltransferase II 215903 7771504 VCM66_0211 Vibrio cholerae M66-2 putative ADP-heptose--LPS heptosyltransferase II YP_002808994.1 214866 D 579112 CDS YP_002808995.1 227080444 7771505 complement(215965..216744) 1 NC_012578.1 putative lipopolysaccharide biosynthesis glycosyltransferase 216744 7771505 VCM66_0212 Vibrio cholerae M66-2 putative lipopolysaccharide biosynthesis glycosyltransferase YP_002808995.1 215965 R 579112 CDS YP_002808996.1 227080445 7771506 complement(216787..217860) 1 NC_012578.1 putative lipopolysaccharide biosynthesis protein 217860 7771506 VCM66_0213 Vibrio cholerae M66-2 putative lipopolysaccharide biosynthesis protein YP_002808996.1 216787 R 579112 CDS YP_002808997.1 227080446 7771507 complement(217863..217958) 1 NC_012578.1 hypothetical protein 217958 7771507 VCM66_0214 Vibrio cholerae M66-2 hypothetical protein YP_002808997.1 217863 R 579112 CDS YP_002808998.1 227080447 7771508 217940..218695 1 NC_012578.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 218695 7771508 VCM66_0215 Vibrio cholerae M66-2 3-deoxy-D-manno-octulosonic-acid kinase YP_002808998.1 217940 D 579112 CDS YP_002808999.1 227080448 7771509 218699..219658 1 NC_012578.1 hypothetical protein 219658 7771509 VCM66_0216 Vibrio cholerae M66-2 hypothetical protein YP_002808999.1 218699 D 579112 CDS YP_002809000.1 227080449 7771510 complement(219662..220591) 1 NC_012578.1 hypothetical protein 220591 7771510 VCM66_0217 Vibrio cholerae M66-2 hypothetical protein YP_002809000.1 219662 R 579112 CDS YP_002809001.1 227080450 7771511 complement(220588..221331) 1 NC_012578.1 hypothetical protein 221331 7771511 VCM66_0218 Vibrio cholerae M66-2 hypothetical protein YP_002809001.1 220588 R 579112 CDS YP_002809002.1 227080451 7771512 complement(221328..222911) 1 NC_012578.1 hypothetical protein 222911 7771512 VCM66_0219 Vibrio cholerae M66-2 hypothetical protein YP_002809002.1 221328 R 579112 CDS YP_002809003.1 227080452 7771513 complement(222902..223282) 1 NC_012578.1 hypothetical protein 223282 7771513 VCM66_0220 Vibrio cholerae M66-2 hypothetical protein YP_002809003.1 222902 R 579112 CDS YP_002809004.1 227080453 7771514 complement(223279..224598) 1 NC_012578.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 224598 kdtA 7771514 kdtA Vibrio cholerae M66-2 3-deoxy-D-manno-octulosonic-acid transferase YP_002809004.1 223279 R 579112 CDS YP_002809005.1 227080454 7771515 complement(224559..225347) 1 NC_012578.1 hypothetical protein 225347 7771515 VCM66_0222 Vibrio cholerae M66-2 hypothetical protein YP_002809005.1 224559 R 579112 CDS YP_002809006.1 227080455 7771516 complement(225344..226393) 1 NC_012578.1 putative lipopolysaccharide biosynthesis protein 226393 7771516 VCM66_0223 Vibrio cholerae M66-2 putative lipopolysaccharide biosynthesis protein YP_002809006.1 225344 R 579112 CDS YP_002809007.1 227080456 7771517 complement(226390..227430) 1 NC_012578.1 ADP-heptose--LPS heptosyltransferase II 227430 rfaF 7771517 rfaF Vibrio cholerae M66-2 ADP-heptose--LPS heptosyltransferase II YP_002809007.1 226390 R 579112 CDS YP_002809008.1 227080457 7771518 complement(227427..228626) 1 NC_012578.1 hypothetical protein 228626 7771518 VCM66_0225 Vibrio cholerae M66-2 hypothetical protein YP_002809008.1 227427 R 579112 CDS YP_002809009.1 227080458 7771519 complement(228628..229194) 1 NC_012578.1 transferase, hexapeptide repeat family 229194 7771519 VCM66_0226 Vibrio cholerae M66-2 transferase, hexapeptide repeat family YP_002809009.1 228628 R 579112 CDS YP_002809010.1 227080459 7773951 complement(231131..232075) 1 NC_012578.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase 232075 rfaD 7773951 rfaD Vibrio cholerae M66-2 ADP-L-glycero-D-mannoheptose-6-epimerase YP_002809010.1 231131 R 579112 CDS YP_002809011.1 227080460 7771521 232517..233914 1 NC_012578.1 mannose-1-phosphate guanylyltransferase 233914 rfbA 7771521 rfbA Vibrio cholerae M66-2 mannose-1-phosphate guanylyltransferase YP_002809011.1 232517 D 579112 CDS YP_002809012.1 227080461 7771522 233917..235308 1 NC_012578.1 phosphomannomutase 235308 rfbB 7771522 rfbB Vibrio cholerae M66-2 phosphomannomutase YP_002809012.1 233917 D 579112 CDS YP_002809013.1 227080462 7771523 235311..236432 1 NC_012578.1 GDP-mannose 4,6-dehydratase 236432 rfbD 7771523 rfbD Vibrio cholerae M66-2 GDP-mannose 4,6-dehydratase YP_002809013.1 235311 D 579112 CDS YP_002809014.1 227080463 7771524 236443..237546 1 NC_012578.1 perosamine synthase 237546 rfbE 7771524 rfbE Vibrio cholerae M66-2 perosamine synthase YP_002809014.1 236443 D 579112 CDS YP_002809015.1 227080464 7771525 237543..238934 1 NC_012578.1 rfbG protein 238934 rfbG 7771525 rfbG Vibrio cholerae M66-2 rfbG protein YP_002809015.1 237543 D 579112 CDS YP_002809016.1 227080465 7771526 238906..239700 1 NC_012578.1 lipopolysaccharide/O-antigen transport protein 239700 rfbH 7771526 rfbH Vibrio cholerae M66-2 lipopolysaccharide/O-antigen transport protein YP_002809016.1 238906 D 579112 CDS YP_002809017.1 227080466 7771527 239639..240454 1 NC_012578.1 lipopolysaccharide/O-antigen transport protein 240454 rfbI 7771527 rfbI Vibrio cholerae M66-2 lipopolysaccharide/O-antigen transport protein YP_002809017.1 239639 D 579112 CDS YP_002809018.1 227080467 7771528 240493..240735 1 NC_012578.1 putative acyl carrier protein 240735 7771528 VCM66_0236 Vibrio cholerae M66-2 putative acyl carrier protein YP_002809018.1 240493 D 579112 CDS YP_002809019.1 227080468 7771529 240741..242156 1 NC_012578.1 rfbL protein 242156 rfbL 7771529 rfbL Vibrio cholerae M66-2 rfbL protein YP_002809019.1 240741 D 579112 CDS YP_002809020.1 227080469 7771530 242165..243289 1 NC_012578.1 putative iron-containing alcohol dehydrogenase 243289 7771530 VCM66_0238 Vibrio cholerae M66-2 putative iron-containing alcohol dehydrogenase YP_002809020.1 242165 D 579112 CDS YP_002809021.1 227080470 7771531 243280..245757 1 NC_012578.1 acyl protein synthase/acyl-CoA reductase 245757 7771531 VCM66_0239 Vibrio cholerae M66-2 acyl protein synthase/acyl-CoA reductase YP_002809021.1 243280 D 579112 CDS YP_002809022.1 227080471 7771532 245827..246393 1 NC_012578.1 acetyltransferase RfbO 246393 7771532 VCM66_0240 Vibrio cholerae M66-2 acetyltransferase RfbO YP_002809022.1 245827 D 579112 CDS YP_002809023.1 227080472 7771533 246543..246623 1 NC_012578.1 IS1004 transposase 246623 7771533 VCM66_0241 Vibrio cholerae M66-2 IS1004 transposase YP_002809023.1 246543 D 579112 CDS YP_002809024.1 227080473 7773952 248086..248946 1 NC_012578.1 rfbT-like protein 248946 7773952 VCM66_0243 Vibrio cholerae M66-2 rfbT-like protein YP_002809024.1 248086 D 579112 CDS YP_002809025.1 227080474 7771535 complement(248981..250213) 1 NC_012578.1 lipopolysaccharide biosynthesis protein RfbV 250213 rfbV 7771535 rfbV Vibrio cholerae M66-2 lipopolysaccharide biosynthesis protein RfbV YP_002809025.1 248981 R 579112 CDS YP_002809026.1 227080475 7771536 complement(250101..251966) 1 NC_012578.1 mannosyl-transferase 251966 rfbU 7771536 rfbU Vibrio cholerae M66-2 mannosyl-transferase YP_002809026.1 250101 R 579112 CDS YP_002809027.1 227080476 7771537 complement(252027..252167) 1 NC_012578.1 hypothetical protein 252167 7771537 VCM66_0246 Vibrio cholerae M66-2 hypothetical protein YP_002809027.1 252027 R 579112 CDS YP_002809028.1 227080477 7771538 252119..253090 1 NC_012578.1 UDP-glucose 4-epimerase 253090 galE-1 7771538 galE-1 Vibrio cholerae M66-2 UDP-glucose 4-epimerase YP_002809028.1 252119 D 579112 CDS YP_002809029.1 227080478 7771539 253098..253652 1 NC_012578.1 putative galactosyl-transferase 253652 7771539 VCM66_0248 Vibrio cholerae M66-2 putative galactosyl-transferase YP_002809029.1 253098 D 579112 CDS YP_002809030.1 227080479 7771540 253795..255162 1 NC_012578.1 hypothetical protein 255162 7771540 VCM66_0249 Vibrio cholerae M66-2 hypothetical protein YP_002809030.1 253795 D 579112 CDS YP_002809031.1 227080480 7771541 complement(255424..256662) 1 NC_012578.1 hypothetical protein 256662 7771541 VCM66_0250 Vibrio cholerae M66-2 hypothetical protein YP_002809031.1 255424 R 579112 CDS YP_002809032.1 227080481 7771542 complement(256717..257289) 1 NC_012578.1 hypothetical protein 257289 7771542 VCM66_0251 Vibrio cholerae M66-2 hypothetical protein YP_002809032.1 256717 R 579112 CDS YP_002809033.1 227080482 7771543 complement(257289..258212) 1 NC_012578.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein 258212 7771543 VCM66_0252 Vibrio cholerae M66-2 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_002809033.1 257289 R 579112 CDS YP_002809034.1 227080483 7771544 258205..258873 1 NC_012578.1 hypothetical protein 258873 7771544 VCM66_0253 Vibrio cholerae M66-2 hypothetical protein YP_002809034.1 258205 D 579112 CDS YP_002809035.1 227080484 7771545 259236..260435 1 NC_012578.1 mannose-6-phosphate isomerase 260435 manA-1 7771545 manA-1 Vibrio cholerae M66-2 mannose-6-phosphate isomerase YP_002809035.1 259236 D 579112 CDS YP_002809036.1 227080485 7771546 260401..261381 1 NC_012578.1 ROK family protein 261381 7771546 VCM66_0255 Vibrio cholerae M66-2 ROK family protein YP_002809036.1 260401 D 579112 CDS YP_002809037.1 227080486 7771547 complement(261729..262787) 1 NC_012578.1 hypothetical protein 262787 7771547 VCM66_0256 Vibrio cholerae M66-2 hypothetical protein YP_002809037.1 261729 R 579112 CDS YP_002809038.1 227080487 7771548 263159..263431 1 NC_012578.1 DNA-binding protein HU 263431 hupA 7771548 hupA Vibrio cholerae M66-2 DNA-binding protein HU YP_002809038.1 263159 D 579112 CDS YP_002809039.1 227080488 7771549 263432..264166 1 NC_012578.1 hypothetical protein 264166 7771549 VCM66_0259 Vibrio cholerae M66-2 hypothetical protein YP_002809039.1 263432 D 579112 CDS YP_002809040.1 227080489 7771550 complement(264266..265555) 1 NC_012578.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 265555 purD 7771550 purD Vibrio cholerae M66-2 phosphoribosylamine--glycine ligase YP_002809040.1 264266 R 579112 CDS YP_002809041.1 227080490 7771551 complement(265614..267206) 1 NC_012578.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 267206 purH 7771551 purH Vibrio cholerae M66-2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002809041.1 265614 R 579112 CDS YP_002809042.1 227080491 7771552 267492..267893 1 NC_012578.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 267893 zntR 7771552 zntR Vibrio cholerae M66-2 zinc-responsive transcriptional regulator YP_002809042.1 267492 D 579112 CDS YP_002809043.1 227080492 7771553 268054..269679 1 NC_012578.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 269679 7771553 VCM66_0263 Vibrio cholerae M66-2 DNA-binding transcriptional activator CadC YP_002809043.1 268054 D 579112 CDS YP_002809044.1 227080493 7771554 270102..270230 1 NC_012578.1 hypothetical protein 270230 7771554 VCM66_0264 Vibrio cholerae M66-2 hypothetical protein YP_002809044.1 270102 D 579112 CDS YP_002809045.1 227080494 7771555 270379..271716 1 NC_012578.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 271716 cadB 7771555 cadB Vibrio cholerae M66-2 lysine/cadaverine antiporter YP_002809045.1 270379 D 579112 CDS YP_002809046.1 227080495 7771556 271760..273961 1 NC_012578.1 lysine decarboxylase 273961 cadA 7771556 cadA Vibrio cholerae M66-2 lysine decarboxylase YP_002809046.1 271760 D 579112 CDS YP_002809047.1 227080496 7771557 complement(274079..275749) 1 NC_012578.1 methyl-accepting chemotaxis protein 275749 7771557 VCM66_0267 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002809047.1 274079 R 579112 CDS YP_002809048.1 227080497 7771558 complement(275984..276661) 1 NC_012578.1 hypothetical protein 276661 7771558 VCM66_0268 Vibrio cholerae M66-2 hypothetical protein YP_002809048.1 275984 R 579112 CDS YP_002809049.1 227080498 7771559 complement(276682..278724) 1 NC_012578.1 TonB system receptor 278724 7771559 VCM66_0269 Vibrio cholerae M66-2 TonB system receptor YP_002809049.1 276682 R 579112 CDS YP_002809050.1 227080499 7771560 complement(278947..279552) 1 NC_012578.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 279552 eda 7771560 eda Vibrio cholerae M66-2 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002809050.1 278947 R 579112 CDS YP_002809051.1 227080500 7771561 complement(279565..280941) 1 NC_012578.1 putative gluconate permease 280941 7771561 VCM66_0271 Vibrio cholerae M66-2 putative gluconate permease YP_002809051.1 279565 R 579112 CDS YP_002809052.1 227080501 7771562 281095..281610 1 NC_012578.1 thermoresistant gluconokinase 281610 gntV 7771562 gntV Vibrio cholerae M66-2 thermoresistant gluconokinase YP_002809052.1 281095 D 579112 CDS YP_002809053.1 227080502 7771563 281547..283403 1 NC_012578.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 283403 edd 7771563 edd Vibrio cholerae M66-2 phosphogluconate dehydratase YP_002809053.1 281547 D 579112 CDS YP_002809054.1 227080503 7771564 complement(283479..284477) 1 NC_012578.1 gluconate utilization system gnt-I transcriptional repressor 284477 gntR 7771564 gntR Vibrio cholerae M66-2 gluconate utilization system gnt-I transcriptional repressor YP_002809054.1 283479 R 579112 CDS YP_002809055.1 227080504 7771565 complement(284615..284911) 1 NC_012578.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 284911 fis 7771565 fis Vibrio cholerae M66-2 DNA-binding protein Fis YP_002809055.1 284615 R 579112 CDS YP_002809056.1 227080505 7771566 complement(284935..285930) 1 NC_012578.1 NifR3/Smm1 family protein 285930 7771566 VCM66_0276 Vibrio cholerae M66-2 NifR3/Smm1 family protein YP_002809056.1 284935 R 579112 CDS YP_002809057.1 227080506 7771567 complement(285911..286003) 1 NC_012578.1 hypothetical protein 286003 7771567 VCM66_0277 Vibrio cholerae M66-2 hypothetical protein YP_002809057.1 285911 R 579112 CDS YP_002809058.1 227080507 7771568 complement(286043..286930) 1 NC_012578.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 286930 prmA 7771568 prmA Vibrio cholerae M66-2 ribosomal protein L11 methyltransferase YP_002809058.1 286043 R 579112 CDS YP_002809059.1 227080508 7771569 complement(286911..287027) 1 NC_012578.1 hypothetical protein 287027 7771569 VCM66_0279 Vibrio cholerae M66-2 hypothetical protein YP_002809059.1 286911 R 579112 CDS YP_002809060.1 227080509 7771570 complement(287139..288482) 1 NC_012578.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 288482 accC 7771570 accC Vibrio cholerae M66-2 acetyl-CoA carboxylase biotin carboxylase subunit YP_002809060.1 287139 R 579112 CDS YP_002809061.1 227080510 7771571 complement(288497..289087) 1 NC_012578.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 289087 accB 7771571 accB Vibrio cholerae M66-2 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002809061.1 288497 R 579112 CDS YP_002809062.1 227080511 7771572 complement(289015..289467) 1 NC_012578.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 289467 aroQ 7771572 aroQ Vibrio cholerae M66-2 3-dehydroquinate dehydratase YP_002809062.1 289015 R 579112 CDS YP_002809063.1 227080512 7771573 complement(289847..291847) 1 NC_012578.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 291847 acs-1 7771573 acs-1 Vibrio cholerae M66-2 acetyl-CoA synthetase YP_002809063.1 289847 R 579112 CDS YP_002809064.1 227080513 7771574 complement(291999..292670) 1 NC_012578.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 292670 7771574 VCM66_0284 Vibrio cholerae M66-2 DNA polymerase III subunit epsilon YP_002809064.1 291999 R 579112 CDS YP_002809065.1 227080514 7771575 complement(292637..294460) 1 NC_012578.1 hypothetical protein 294460 7771575 VCM66_0285 Vibrio cholerae M66-2 hypothetical protein YP_002809065.1 292637 R 579112 CDS YP_002809066.1 227080515 7771576 complement(294415..294621) 1 NC_012578.1 hypothetical protein 294621 7771576 VCM66_0286 Vibrio cholerae M66-2 hypothetical protein YP_002809066.1 294415 R 579112 CDS YP_002809067.1 227080516 7771577 294720..295910 1 NC_012578.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 295910 7771577 VCM66_0287 Vibrio cholerae M66-2 putative 3-phenylpropionic acid transporter YP_002809067.1 294720 D 579112 CDS YP_002809068.1 227080517 7771578 296003..299446 1 NC_012578.1 sensor histidine kinase 299446 7771578 VCM66_0288 Vibrio cholerae M66-2 sensor histidine kinase YP_002809068.1 296003 D 579112 CDS YP_002809069.1 227080518 7771579 complement(299569..301062) 1 NC_012578.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 301062 gppA 7771579 gppA Vibrio cholerae M66-2 guanosine pentaphosphate phosphohydrolase YP_002809069.1 299569 R 579112 CDS YP_002809070.1 227080519 7771580 complement(301070..302386) 1 NC_012578.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 302386 rhlB 7771580 rhlB Vibrio cholerae M66-2 ATP-dependent RNA helicase RhlB YP_002809070.1 301070 R 579112 CDS YP_002809071.1 227080520 7771581 302498..302824 1 NC_012578.1 thioredoxin 302824 trxA 7771581 trxA Vibrio cholerae M66-2 thioredoxin YP_002809071.1 302498 D 579112 CDS YP_002809072.1 227080521 7771582 303022..304281 1 NC_012578.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 304281 rho 7771582 rho Vibrio cholerae M66-2 transcription termination factor Rho YP_002809072.1 303022 D 579112 CDS YP_002809073.1 227080522 7771583 304380..305372 1 NC_012578.1 hypothetical protein 305372 7771583 VCM66_0293 Vibrio cholerae M66-2 hypothetical protein YP_002809073.1 304380 D 579112 CDS YP_002809074.1 227080523 7771584 305454..307295 1 NC_012578.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 307295 7771584 VCM66_0294 Vibrio cholerae M66-2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002809074.1 305454 D 579112 CDS YP_002809075.1 227080524 7771585 307292..307561 1 NC_012578.1 ferredoxin 307561 7771585 VCM66_0295 Vibrio cholerae M66-2 ferredoxin YP_002809075.1 307292 D 579112 CDS YP_002809076.1 227080525 7771586 307577..308287 1 NC_012578.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 308287 fre 7771586 fre Vibrio cholerae M66-2 FMN reductase YP_002809076.1 307577 D 579112 CDS YP_002809077.1 227080526 7771587 308447..308542 1 NC_012578.1 hypothetical protein 308542 7771587 VCM66_0297 Vibrio cholerae M66-2 hypothetical protein YP_002809077.1 308447 D 579112 CDS YP_002809078.1 227080527 7774008 complement(314437..315777) 1 NC_012578.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 315777 pssA 7774008 pssA Vibrio cholerae M66-2 phosphatidylserine synthase YP_002809078.1 314437 R 579112 CDS YP_002809079.1 227080528 7771589 315748..315900 1 NC_012578.1 hypothetical protein 315900 7771589 VCM66_0300 Vibrio cholerae M66-2 hypothetical protein YP_002809079.1 315748 D 579112 CDS YP_002809080.1 227080529 7771590 complement(315872..316318) 1 NC_012578.1 hypothetical protein 316318 7771590 VCM66_0301 Vibrio cholerae M66-2 hypothetical protein YP_002809080.1 315872 R 579112 CDS YP_002809081.1 227080530 7771591 316331..317404 1 NC_012578.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 317404 murB 7771591 murB Vibrio cholerae M66-2 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002809081.1 316331 D 579112 CDS YP_002809082.1 227080531 7771592 317401..318363 1 NC_012578.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 318363 birA 7771592 birA Vibrio cholerae M66-2 biotin--protein ligase YP_002809082.1 317401 D 579112 CDS YP_002809083.1 227080532 7771593 complement(318413..319540) 1 NC_012578.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 319540 coaA 7771593 coaA Vibrio cholerae M66-2 pantothenate kinase YP_002809083.1 318413 R 579112 CDS YP_002809084.1 227080533 7774068 320052..321236 1 NC_012578.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 321236 tufB 7774068 tufB Vibrio cholerae M66-2 elongation factor Tu YP_002809084.1 320052 D 579112 CDS YP_002809085.1 227080534 7771595 321445..321840 1 NC_012578.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 321840 secE 7771595 secE Vibrio cholerae M66-2 preprotein translocase subunit SecE YP_002809085.1 321445 D 579112 CDS YP_002809086.1 227080535 7771596 321856..322404 1 NC_012578.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 322404 nusG 7771596 nusG Vibrio cholerae M66-2 transcription antitermination protein NusG YP_002809086.1 321856 D 579112 CDS YP_002809087.1 227080536 7771597 322535..322963 1 NC_012578.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 322963 rplK 7771597 rplK Vibrio cholerae M66-2 50S ribosomal protein L11 YP_002809087.1 322535 D 579112 CDS YP_002809088.1 227080537 7771598 322968..323669 1 NC_012578.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 323669 rplA 7771598 rplA Vibrio cholerae M66-2 50S ribosomal protein L1 YP_002809088.1 322968 D 579112 CDS YP_002809089.1 227080538 7771599 323939..324427 1 NC_012578.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 324427 rplJ 7771599 rplJ Vibrio cholerae M66-2 50S ribosomal protein L10 YP_002809089.1 323939 D 579112 CDS YP_002809090.1 227080539 7771600 324494..324859 1 NC_012578.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 324859 rplL 7771600 rplL Vibrio cholerae M66-2 50S ribosomal protein L7/L12 YP_002809090.1 324494 D 579112 CDS YP_002809091.1 227080540 7771601 324998..329125 1 NC_012578.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 329125 rpoB 7771601 rpoB Vibrio cholerae M66-2 DNA-directed RNA polymerase subunit beta YP_002809091.1 324998 D 579112 CDS YP_002809092.1 227080541 7771602 329230..333435 1 NC_012578.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 333435 rpoC 7771602 rpoC Vibrio cholerae M66-2 DNA-directed RNA polymerase subunit beta' YP_002809092.1 329230 D 579112 CDS YP_002809093.1 227080542 7771603 complement(333546..334040) 1 NC_012578.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 334040 rsd 7771603 rsd Vibrio cholerae M66-2 anti-RNA polymerase sigma 70 factor YP_002809093.1 333546 R 579112 CDS YP_002809094.1 227080543 7771604 334185..334994 1 NC_012578.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 334994 nudC 7771604 nudC Vibrio cholerae M66-2 NADH pyrophosphatase YP_002809094.1 334185 D 579112 CDS YP_002809095.1 227080544 7771605 335237..336316 1 NC_012578.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 336316 hemE 7771605 hemE Vibrio cholerae M66-2 uroporphyrinogen decarboxylase YP_002809095.1 335237 D 579112 CDS YP_002809096.1 227080545 7771606 336322..337050 1 NC_012578.1 TetR family transcriptional regulator 337050 7771606 VCM66_0317 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002809096.1 336322 D 579112 CDS YP_002809097.1 227080546 7771607 337137..338096 1 NC_012578.1 hypothetical protein 338096 7771607 VCM66_0318 Vibrio cholerae M66-2 hypothetical protein YP_002809097.1 337137 D 579112 CDS YP_002809098.1 227080547 7771608 complement(338093..339241) 1 NC_012578.1 NlpD-like protein 339241 7771608 VCM66_0319 Vibrio cholerae M66-2 NlpD-like protein YP_002809098.1 338093 R 579112 CDS YP_002809099.1 227080548 7771609 complement(339410..340942) 1 NC_012578.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 340942 yibO 7771609 yibO Vibrio cholerae M66-2 phosphoglyceromutase YP_002809099.1 339410 R 579112 CDS YP_002809100.1 227080549 7771610 complement(341085..342026) 1 NC_012578.1 hypothetical protein 342026 7771610 VCM66_0321 Vibrio cholerae M66-2 hypothetical protein YP_002809100.1 341085 R 579112 CDS YP_002809101.1 227080550 7771611 complement(342124..343560) 1 NC_012578.1 putative transporter 343560 7771611 VCM66_0322 Vibrio cholerae M66-2 putative transporter YP_002809101.1 342124 R 579112 CDS YP_002809102.1 227080551 7771612 complement(343747..344604) 1 NC_012578.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 344604 psd 7771612 psd Vibrio cholerae M66-2 phosphatidylserine decarboxylase YP_002809102.1 343747 R 579112 CDS YP_002809103.1 227080552 7771613 complement(344700..345761) 1 NC_012578.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 345761 rsgA 7771613 rsgA Vibrio cholerae M66-2 ribosome-associated GTPase YP_002809103.1 344700 R 579112 CDS YP_002809104.1 227080553 7771614 345884..346429 1 NC_012578.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 346429 orn 7771614 orn Vibrio cholerae M66-2 oligoribonuclease YP_002809104.1 345884 D 579112 CDS YP_002809105.1 227080554 7774049 complement(348302..349411) 1 NC_012578.1 iron-sulfur cluster-binding protein 349411 7774049 VCM66_0326 Vibrio cholerae M66-2 iron-sulfur cluster-binding protein YP_002809105.1 348302 R 579112 CDS YP_002809106.1 227080555 7771616 349514..350080 1 NC_012578.1 hypothetical protein 350080 7771616 VCM66_0327 Vibrio cholerae M66-2 hypothetical protein YP_002809106.1 349514 D 579112 CDS YP_002809107.1 227080556 7771617 350047..351792 1 NC_012578.1 N-acetylmuramoyl-L-alanine amidase 351792 amiB 7771617 amiB Vibrio cholerae M66-2 N-acetylmuramoyl-L-alanine amidase YP_002809107.1 350047 D 579112 CDS YP_002809108.1 227080557 7771618 351799..353760 1 NC_012578.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 353760 mutL 7771618 mutL Vibrio cholerae M66-2 DNA mismatch repair protein YP_002809108.1 351799 D 579112 CDS YP_002809109.1 227080558 7771619 353757..354704 1 NC_012578.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 354704 miaA 7771619 miaA Vibrio cholerae M66-2 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002809109.1 353757 D 579112 CDS YP_002809110.1 227080559 7771620 354876..355139 1 NC_012578.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 355139 hfq 7771620 hfq Vibrio cholerae M66-2 RNA-binding protein Hfq YP_002809110.1 354876 D 579112 CDS YP_002809111.1 227080560 7771621 355172..356461 1 NC_012578.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 356461 hflX 7771621 hflX Vibrio cholerae M66-2 putative GTPase HflX YP_002809111.1 355172 D 579112 CDS YP_002809112.1 227080561 7771622 356507..357694 1 NC_012578.1 hflK protein 357694 hflK 7771622 hflK Vibrio cholerae M66-2 hflK protein YP_002809112.1 356507 D 579112 CDS YP_002809113.1 227080562 7771623 357697..358677 1 NC_012578.1 hflC protein 358677 hflC 7771623 hflC Vibrio cholerae M66-2 hflC protein YP_002809113.1 357697 D 579112 CDS YP_002809114.1 227080563 7771624 358720..358926 1 NC_012578.1 hypothetical protein 358926 7771624 VCM66_0335 Vibrio cholerae M66-2 hypothetical protein YP_002809114.1 358720 D 579112 CDS YP_002809115.1 227080564 7771625 complement(358967..359185) 1 NC_012578.1 hypothetical protein 359185 slyX 7771625 slyX Vibrio cholerae M66-2 hypothetical protein YP_002809115.1 358967 R 579112 CDS YP_002809116.1 227080565 7771626 complement(359197..360180) 1 NC_012578.1 hypothetical protein 360180 7771626 VCM66_0337 Vibrio cholerae M66-2 hypothetical protein YP_002809116.1 359197 R 579112 CDS YP_002809117.1 227080566 7771627 360317..361096 1 NC_012578.1 FKBP-type peptidyl-prolyl cis-trans isomerase 361096 fkpA 7771627 fkpA Vibrio cholerae M66-2 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002809117.1 360317 D 579112 CDS YP_002809118.1 227080567 7771628 361295..362017 1 NC_012578.1 hypothetical protein 362017 7771628 VCM66_0339 Vibrio cholerae M66-2 hypothetical protein YP_002809118.1 361295 D 579112 CDS YP_002809119.1 227080568 7771629 362014..362409 1 NC_012578.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 362409 7771629 VCM66_0340 Vibrio cholerae M66-2 sulfur transfer complex subunit TusD YP_002809119.1 362014 D 579112 CDS YP_002809120.1 227080569 7771630 362406..362762 1 NC_012578.1 hypothetical protein 362762 7771630 VCM66_0341 Vibrio cholerae M66-2 hypothetical protein YP_002809120.1 362406 D 579112 CDS YP_002809121.1 227080570 7771631 362772..363047 1 NC_012578.1 hypothetical protein 363047 7771631 VCM66_0342 Vibrio cholerae M66-2 hypothetical protein YP_002809121.1 362772 D 579112 CDS YP_002809122.1 227080571 7771632 363232..363606 1 NC_012578.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 363606 rpsL 7771632 rpsL Vibrio cholerae M66-2 30S ribosomal protein S12 YP_002809122.1 363232 D 579112 CDS YP_002809123.1 227080572 7771633 363722..364192 1 NC_012578.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 364192 rpsG 7771633 rpsG Vibrio cholerae M66-2 30S ribosomal protein S7 YP_002809123.1 363722 D 579112 CDS YP_002809124.1 227080573 7771634 364268..366364 1 NC_012578.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 366364 fusA-1 7771634 fusA-1 Vibrio cholerae M66-2 elongation factor G YP_002809124.1 364268 D 579112 CDS YP_002809125.1 227080574 7771635 366487..367671 1 NC_012578.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 367671 tufA 7771635 tufA Vibrio cholerae M66-2 elongation factor Tu YP_002809125.1 366487 D 579112 CDS YP_002809126.1 227080575 7771636 complement(367792..367902) 1 NC_012578.1 hypothetical protein 367902 7771636 VCM66_0347 Vibrio cholerae M66-2 hypothetical protein YP_002809126.1 367792 R 579112 CDS YP_002809127.1 227080576 7771637 367974..368162 1 NC_012578.1 bacterioferritin-associated ferredoxin 368162 bfd 7771637 bfd Vibrio cholerae M66-2 bacterioferritin-associated ferredoxin YP_002809127.1 367974 D 579112 CDS YP_002809128.1 227080577 7771638 368232..368708 1 NC_012578.1 bacterioferritin 368708 bfr 7771638 bfr Vibrio cholerae M66-2 bacterioferritin YP_002809128.1 368232 D 579112 CDS YP_002809129.1 227080578 7771639 368920..369288 1 NC_012578.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 369288 rpsF 7771639 rpsF Vibrio cholerae M66-2 30S ribosomal protein S6 YP_002809129.1 368920 D 579112 CDS YP_002809130.1 227080579 7771640 369296..369598 1 NC_012578.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 369598 priB 7771640 priB Vibrio cholerae M66-2 primosomal replication protein N YP_002809130.1 369296 D 579112 CDS YP_002809131.1 227080580 7771641 369614..369841 1 NC_012578.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 369841 rpsR 7771641 rpsR Vibrio cholerae M66-2 30S ribosomal protein S18 YP_002809131.1 369614 D 579112 CDS YP_002809132.1 227080581 7771642 369875..370324 1 NC_012578.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 370324 rplI 7771642 rplI Vibrio cholerae M66-2 50S ribosomal protein L9 YP_002809132.1 369875 D 579112 CDS YP_002809133.1 227080582 7771643 complement(370386..371195) 1 NC_012578.1 hypothetical protein 371195 7771643 VCM66_0354 Vibrio cholerae M66-2 hypothetical protein YP_002809133.1 370386 R 579112 CDS YP_002809134.1 227080583 7771644 371321..372727 1 NC_012578.1 unwinds double stranded DNA; replicative DNA helicase 372727 dnaB 7771644 dnaB Vibrio cholerae M66-2 replicative DNA helicase YP_002809134.1 371321 D 579112 CDS YP_002809135.1 227080584 7771645 372699..373826 1 NC_012578.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 373826 alr 7771645 alr Vibrio cholerae M66-2 alanine racemase YP_002809135.1 372699 D 579112 CDS YP_002809136.1 227080585 7771646 complement(373909..374328) 1 NC_012578.1 hypothetical protein 374328 7771646 VCM66_0357 Vibrio cholerae M66-2 hypothetical protein YP_002809136.1 373909 R 579112 CDS YP_002809137.1 227080586 7771647 374613..376265 1 NC_012578.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 376265 pgi 7771647 pgi Vibrio cholerae M66-2 glucose-6-phosphate isomerase YP_002809137.1 374613 D 579112 CDS YP_002809138.1 227080587 7771648 complement(376298..376405) 1 NC_012578.1 hypothetical protein 376405 7771648 VCM66_0359 Vibrio cholerae M66-2 hypothetical protein YP_002809138.1 376298 R 579112 CDS YP_002809139.1 227080588 7771649 376468..377646 1 NC_012578.1 hypothetical protein 377646 7771649 VCM66_0360 Vibrio cholerae M66-2 hypothetical protein YP_002809139.1 376468 D 579112 CDS YP_002809140.1 227080589 7771650 complement(377763..378224) 1 NC_012578.1 hypothetical protein 378224 7771650 VCM66_0361 Vibrio cholerae M66-2 hypothetical protein YP_002809140.1 377763 R 579112 CDS YP_002809141.1 227080590 7771651 complement(378234..378701) 1 NC_012578.1 putative zinc uptake regulation protein 378701 7771651 VCM66_0362 Vibrio cholerae M66-2 putative zinc uptake regulation protein YP_002809141.1 378234 R 579112 CDS YP_002809142.1 227080591 7771652 379056..380039 1 NC_012578.1 tRNA-dihydrouridine synthase A 380039 7771652 VCM66_0363 Vibrio cholerae M66-2 tRNA-dihydrouridine synthase A YP_002809142.1 379056 D 579112 CDS YP_002809143.1 227080592 7771653 380200..380412 1 NC_012578.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 380412 pspG 7771653 pspG Vibrio cholerae M66-2 phage shock protein G YP_002809143.1 380200 D 579112 CDS YP_002809144.1 227080593 7771654 380501..381166 1 NC_012578.1 hypothetical protein 381166 7771654 VCM66_0366 Vibrio cholerae M66-2 hypothetical protein YP_002809144.1 380501 D 579112 CDS YP_002809145.1 227080594 7771655 381120..381290 1 NC_012578.1 hypothetical protein 381290 7771655 VCM66_0367 Vibrio cholerae M66-2 hypothetical protein YP_002809145.1 381120 D 579112 CDS YP_002809146.1 227080595 7771656 381248..381517 1 NC_012578.1 hypothetical protein 381517 7771656 VCM66_0368 Vibrio cholerae M66-2 hypothetical protein YP_002809146.1 381248 D 579112 CDS YP_002809147.1 227080596 7771657 381603..383447 1 NC_012578.1 sulfite reductase (NADPH) flavoprotein alpha-component 383447 cysJ 7771657 cysJ Vibrio cholerae M66-2 sulfite reductase (NADPH) flavoprotein alpha-component YP_002809147.1 381603 D 579112 CDS YP_002809148.1 227080597 7771658 383447..385180 1 NC_012578.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 385180 cysI 7771658 cysI Vibrio cholerae M66-2 sulfite reductase subunit beta YP_002809148.1 383447 D 579112 CDS YP_002809149.1 227080598 7771659 385173..385934 1 NC_012578.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 385934 cysH 7771659 cysH Vibrio cholerae M66-2 phosphoadenosine phosphosulfate reductase YP_002809149.1 385173 D 579112 CDS YP_002809150.1 227080599 7771660 386071..386166 1 NC_012578.1 hypothetical protein 386166 7771660 VCM66_0372 Vibrio cholerae M66-2 hypothetical protein YP_002809150.1 386071 D 579112 CDS YP_002809151.1 227080600 7774009 complement(392233..393567) 1 NC_012578.1 putative Na+/H+ antiporter 393567 7774009 VCM66_0374 Vibrio cholerae M66-2 putative Na+/H+ antiporter YP_002809151.1 392233 R 579112 CDS YP_002809152.1 227080601 7771662 393764..397444 1 NC_012578.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 397444 metH 7771662 metH Vibrio cholerae M66-2 B12-dependent methionine synthase YP_002809152.1 393764 D 579112 CDS YP_002809153.1 227080602 7771663 complement(397517..398956) 1 NC_012578.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 398956 lysC 7771663 lysC Vibrio cholerae M66-2 aspartate kinase III YP_002809153.1 397517 R 579112 CDS YP_002809154.1 227080603 7771664 399336..400454 1 NC_012578.1 class V aminotransferase 400454 7771664 VCM66_0377 Vibrio cholerae M66-2 class V aminotransferase YP_002809154.1 399336 D 579112 CDS YP_002809155.1 227080604 7771665 complement(400533..402326) 1 NC_012578.1 hypothetical protein 402326 7771665 VCM66_0378 Vibrio cholerae M66-2 hypothetical protein YP_002809155.1 400533 R 579112 CDS YP_002809156.1 227080605 7771666 complement(402382..405204) 1 NC_012578.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 405204 uvrA 7771666 uvrA Vibrio cholerae M66-2 excinuclease ABC subunit A YP_002809156.1 402382 R 579112 CDS YP_002809157.1 227080606 7771667 complement(405360..406235) 1 NC_012578.1 UTP--glucose-1-phosphate uridylyltransferase 406235 galU 7771667 galU Vibrio cholerae M66-2 UTP--glucose-1-phosphate uridylyltransferase YP_002809157.1 405360 R 579112 CDS YP_002809158.1 227080607 7771668 complement(406405..407049) 1 NC_012578.1 LuxR family transcriptional regulator 407049 7771668 VCM66_0381 Vibrio cholerae M66-2 LuxR family transcriptional regulator YP_002809158.1 406405 R 579112 CDS YP_002809159.1 227080608 7771669 407341..407874 1 NC_012578.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 407874 ssb 7771669 ssb Vibrio cholerae M66-2 single-stranded DNA-binding protein YP_002809159.1 407341 D 579112 CDS YP_002809160.1 227080609 7771670 407989..410010 1 NC_012578.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 410010 mshH 7771670 mshH Vibrio cholerae M66-2 regulatory protein CsrD YP_002809160.1 407989 D 579112 CDS YP_002809161.1 227080610 7771671 410023..411462 1 NC_012578.1 MSHA biogenesis protein MshI 411462 mshI 7771671 mshI Vibrio cholerae M66-2 MSHA biogenesis protein MshI YP_002809161.1 410023 D 579112 CDS YP_002809162.1 227080611 7771672 411459..412109 1 NC_012578.1 MSHA biogenesis protein MshJ 412109 mshJ 7771672 mshJ Vibrio cholerae M66-2 MSHA biogenesis protein MshJ YP_002809162.1 411459 D 579112 CDS YP_002809163.1 227080612 7771673 412102..412419 1 NC_012578.1 MSHA biogenesis protein MshK 412419 mshK 7771673 mshK Vibrio cholerae M66-2 MSHA biogenesis protein MshK YP_002809163.1 412102 D 579112 CDS YP_002809164.1 227080613 7771674 412434..414113 1 NC_012578.1 MSHA biogenesis protein MshL 414113 mshL 7771674 mshL Vibrio cholerae M66-2 MSHA biogenesis protein MshL YP_002809164.1 412434 D 579112 CDS YP_002809165.1 227080614 7771675 414118..414963 1 NC_012578.1 MSHA biogenesis protein MshM 414963 mshM 7771675 mshM Vibrio cholerae M66-2 MSHA biogenesis protein MshM YP_002809165.1 414118 D 579112 CDS YP_002809166.1 227080615 7771676 414942..416111 1 NC_012578.1 MSHA biogenesis protein MshN 416111 mshN 7771676 mshN Vibrio cholerae M66-2 MSHA biogenesis protein MshN YP_002809166.1 414942 D 579112 CDS YP_002809167.1 227080616 7771677 416101..417828 1 NC_012578.1 MSHA biogenesis protein MshE 417828 mshE 7771677 mshE Vibrio cholerae M66-2 MSHA biogenesis protein MshE YP_002809167.1 416101 D 579112 CDS YP_002809168.1 227080617 7771678 417837..419060 1 NC_012578.1 MSHA biogenesis protein MshG 419060 mshG 7771678 mshG Vibrio cholerae M66-2 MSHA biogenesis protein MshG YP_002809168.1 417837 D 579112 CDS YP_002809169.1 227080618 7771679 419063..419515 1 NC_012578.1 MSHA biogenesis protein MshF 419515 mshF 7771679 mshF Vibrio cholerae M66-2 MSHA biogenesis protein MshF YP_002809169.1 419063 D 579112 CDS YP_002809170.1 227080619 7771680 419560..420150 1 NC_012578.1 MSHA pilin protein MshB 420150 mshB 7771680 mshB Vibrio cholerae M66-2 MSHA pilin protein MshB YP_002809170.1 419560 D 579112 CDS YP_002809171.1 227080620 7771681 420176..420712 1 NC_012578.1 MSHA pilin protein MshA 420712 mshA 7771681 mshA Vibrio cholerae M66-2 MSHA pilin protein MshA YP_002809171.1 420176 D 579112 CDS YP_002809172.1 227080621 7771682 420749..421237 1 NC_012578.1 MSHA pilin protein MshC 421237 mshC 7771682 mshC Vibrio cholerae M66-2 MSHA pilin protein MshC YP_002809172.1 420749 D 579112 CDS YP_002809173.1 227080622 7771683 421185..421796 1 NC_012578.1 MSHA pilin protein MshD 421796 mshD 7771683 mshD Vibrio cholerae M66-2 MSHA pilin protein MshD YP_002809173.1 421185 D 579112 CDS YP_002809174.1 227080623 7771684 421796..422566 1 NC_012578.1 hypothetical protein 422566 7771684 VCM66_0397 Vibrio cholerae M66-2 hypothetical protein YP_002809174.1 421796 D 579112 CDS YP_002809175.1 227080624 7771685 422532..422963 1 NC_012578.1 hypothetical protein 422963 7771685 VCM66_0398 Vibrio cholerae M66-2 hypothetical protein YP_002809175.1 422532 D 579112 CDS YP_002809176.1 227080625 7771686 422956..426714 1 NC_012578.1 hypothetical protein 426714 7771686 VCM66_0399 Vibrio cholerae M66-2 hypothetical protein YP_002809176.1 422956 D 579112 CDS YP_002809177.1 227080626 7771687 426882..427925 1 NC_012578.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 427925 mreB 7771687 mreB Vibrio cholerae M66-2 rod shape-determining protein MreB YP_002809177.1 426882 D 579112 CDS YP_002809178.1 227080627 7771688 427982..428872 1 NC_012578.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 428872 mreC 7771688 mreC Vibrio cholerae M66-2 rod shape-determining protein MreC YP_002809178.1 427982 D 579112 CDS YP_002809179.1 227080628 7771689 428859..429347 1 NC_012578.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 429347 mreD 7771689 mreD Vibrio cholerae M66-2 rod shape-determining protein MreD YP_002809179.1 428859 D 579112 CDS YP_002809180.1 227080629 7771690 429290..429907 1 NC_012578.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 429907 maf 7771690 maf Vibrio cholerae M66-2 Maf-like protein YP_002809180.1 429290 D 579112 CDS YP_002809181.1 227080630 7771691 429933..431402 1 NC_012578.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 431402 cafA 7771691 cafA Vibrio cholerae M66-2 ribonuclease G YP_002809181.1 429933 D 579112 CDS YP_002809182.1 227080631 7771692 431415..435290 1 NC_012578.1 hypothetical protein 435290 7771692 VCM66_0405 Vibrio cholerae M66-2 hypothetical protein YP_002809182.1 431415 D 579112 CDS YP_002809183.1 227080632 7771693 435299..436126 1 NC_012578.1 hypothetical protein 436126 7771693 VCM66_0406 Vibrio cholerae M66-2 hypothetical protein YP_002809183.1 435299 D 579112 CDS YP_002809184.1 227080633 7771694 436126..437571 1 NC_012578.1 tldD protein 437571 tldD 7771694 tldD Vibrio cholerae M66-2 tldD protein YP_002809184.1 436126 D 579112 CDS YP_002809185.1 227080634 7771695 complement(437667..438890) 1 NC_012578.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 438890 arcA 7771695 arcA Vibrio cholerae M66-2 arginine deiminase YP_002809185.1 437667 R 579112 CDS YP_002809186.1 227080635 7771696 439617..440039 1 NC_012578.1 hypothetical protein 440039 7771696 VCM66_0409 Vibrio cholerae M66-2 hypothetical protein YP_002809186.1 439617 D 579112 CDS YP_002809187.1 227080636 7771697 440186..440983 1 NC_012578.1 hypothetical protein 440983 7771697 VCM66_0410 Vibrio cholerae M66-2 hypothetical protein YP_002809187.1 440186 D 579112 CDS YP_002809188.1 227080637 7771698 complement(441052..441435) 1 NC_012578.1 hypothetical protein 441435 7771698 VCM66_0411 Vibrio cholerae M66-2 hypothetical protein YP_002809188.1 441052 R 579112 CDS YP_002809189.1 227080638 7771699 441454..441564 1 NC_012578.1 hypothetical protein 441564 7771699 VCM66_0412 Vibrio cholerae M66-2 hypothetical protein YP_002809189.1 441454 D 579112 CDS YP_002809190.1 227080639 7771700 complement(441586..442023) 1 NC_012578.1 Universal stress protein F 442023 7771700 VCM66_0413 Vibrio cholerae M66-2 Universal stress protein F YP_002809190.1 441586 R 579112 CDS YP_002809191.1 227080640 7771701 complement(442145..444709) 1 NC_012578.1 hypothetical protein 444709 7771701 VCM66_0414 Vibrio cholerae M66-2 hypothetical protein YP_002809191.1 442145 R 579112 CDS YP_002809192.1 227080641 7771702 complement(444880..445866) 1 NC_012578.1 immunogenic protein 445866 7771702 VCM66_0415 Vibrio cholerae M66-2 immunogenic protein YP_002809192.1 444880 R 579112 CDS YP_002809193.1 227080642 7771703 complement(446172..446705) 1 NC_012578.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 446705 argR 7771703 argR Vibrio cholerae M66-2 arginine repressor YP_002809193.1 446172 R 579112 CDS YP_002809194.1 227080643 7771704 446844..447905 1 NC_012578.1 oxidizes malate to oxaloacetate; malate dehydrogenase 447905 mdh 7771704 mdh Vibrio cholerae M66-2 malate dehydrogenase YP_002809194.1 446844 D 579112 CDS YP_002809195.1 227080644 7771705 448379..449785 1 NC_012578.1 arginine/ornithine antiporter 449785 7771705 VCM66_0418 Vibrio cholerae M66-2 arginine/ornithine antiporter YP_002809195.1 448379 D 579112 CDS YP_002809196.1 227080645 7771706 complement(449934..450980) 1 NC_012578.1 octaprenyl-diphosphate synthase 450980 ispB 7771706 ispB Vibrio cholerae M66-2 octaprenyl-diphosphate synthase YP_002809196.1 449934 R 579112 CDS YP_002809197.1 227080646 7771707 451176..451487 1 NC_012578.1 50S ribosomal protein L21 451487 rplU 7771707 rplU Vibrio cholerae M66-2 50S ribosomal protein L21 YP_002809197.1 451176 D 579112 CDS YP_002809198.1 227080647 7771708 451508..451768 1 NC_012578.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 451768 rpmA 7771708 rpmA Vibrio cholerae M66-2 50S ribosomal protein L27 YP_002809198.1 451508 D 579112 CDS YP_002809199.1 227080648 7771709 451969..453156 1 NC_012578.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 453156 obgE 7771709 obgE Vibrio cholerae M66-2 GTPase ObgE YP_002809199.1 451969 D 579112 CDS YP_002809200.1 227080649 7771710 453170..454039 1 NC_012578.1 putative Inner membrane protein 454039 7771710 VCM66_0423 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809200.1 453170 D 579112 CDS YP_002809201.1 227080650 7771711 454027..454512 1 NC_012578.1 hypothetical protein 454512 7771711 VCM66_0424 Vibrio cholerae M66-2 hypothetical protein YP_002809201.1 454027 D 579112 CDS YP_002809202.1 227080651 7771712 454525..455022 1 NC_012578.1 dihydrofolate reductase 455022 folA 7771712 folA Vibrio cholerae M66-2 dihydrofolate reductase YP_002809202.1 454525 D 579112 CDS YP_002809203.1 227080652 7771713 complement(455171..455980) 1 NC_012578.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 455980 apaH 7771713 apaH Vibrio cholerae M66-2 diadenosine tetraphosphatase YP_002809203.1 455171 R 579112 CDS YP_002809204.1 227080653 7771714 complement(455991..456371) 1 NC_012578.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 456371 apaG 7771714 apaG Vibrio cholerae M66-2 ApaG protein YP_002809204.1 455991 R 579112 CDS YP_002809205.1 227080654 7771715 complement(456443..457291) 1 NC_012578.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 457291 ksgA 7771715 ksgA Vibrio cholerae M66-2 dimethyladenosine transferase YP_002809205.1 456443 R 579112 CDS YP_002809206.1 227080655 7771716 complement(457272..458264) 1 NC_012578.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 458264 pdxA 7771716 pdxA Vibrio cholerae M66-2 4-hydroxythreonine-4-phosphate dehydrogenase YP_002809206.1 457272 R 579112 CDS YP_002809207.1 227080656 7771717 complement(458254..459549) 1 NC_012578.1 survival protein SurA 459549 surA 7771717 surA Vibrio cholerae M66-2 survival protein SurA YP_002809207.1 458254 R 579112 CDS YP_002809208.1 227080657 7771718 complement(459602..462001) 1 NC_012578.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 462001 imp 7771718 imp Vibrio cholerae M66-2 organic solvent tolerance protein YP_002809208.1 459602 R 579112 CDS YP_002809209.1 227080658 7771719 462148..463002 1 NC_012578.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 463002 djlA 7771719 djlA Vibrio cholerae M66-2 Dna-J like membrane chaperone protein YP_002809209.1 462148 D 579112 CDS YP_002809210.1 227080659 7774057 complement(464049..465674) 1 NC_012578.1 methyl-accepting chemotaxis protein 465674 7774057 VCM66_0434 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002809210.1 464049 R 579112 CDS YP_002809211.1 227080660 7774055 complement(466438..467628) 1 NC_012578.1 membrane-bound lytic murein transglycosylase C 467628 mltC 7774055 mltC Vibrio cholerae M66-2 membrane-bound lytic murein transglycosylase C YP_002809211.1 466438 R 579112 CDS YP_002809212.1 227080661 7771722 complement(467667..467939) 1 NC_012578.1 hypothetical protein 467939 7771722 VCM66_0436 Vibrio cholerae M66-2 hypothetical protein YP_002809212.1 467667 R 579112 CDS YP_002809213.1 227080662 7771723 complement(467953..469014) 1 NC_012578.1 A/G-specific adenine glycosylase 469014 mutY 7771723 mutY Vibrio cholerae M66-2 A/G-specific adenine glycosylase YP_002809213.1 467953 R 579112 CDS YP_002809214.1 227080663 7771724 469254..469973 1 NC_012578.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 469973 trmB 7771724 trmB Vibrio cholerae M66-2 tRNA (guanine-N(7)-)-methyltransferase YP_002809214.1 469254 D 579112 CDS YP_002809215.1 227080664 7771725 470054..471004 1 NC_012578.1 catalyzes the formation of glutamate from glutamine; glutaminase 471004 7771725 VCM66_0439 Vibrio cholerae M66-2 glutaminase YP_002809215.1 470054 D 579112 CDS YP_002809216.1 227080665 7771726 complement(471239..472414) 1 NC_012578.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 472414 7771726 VCM66_0440 Vibrio cholerae M66-2 coproporphyrinogen III oxidase YP_002809216.1 471239 R 579112 CDS YP_002809217.1 227080666 7771727 complement(472408..473010) 1 NC_012578.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 473010 7771727 VCM66_0441 Vibrio cholerae M66-2 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002809217.1 472408 R 579112 CDS YP_002809218.1 227080667 7771728 complement(473080..473511) 1 NC_012578.1 hypothetical protein 473511 7771728 VCM66_0442 Vibrio cholerae M66-2 hypothetical protein YP_002809218.1 473080 R 579112 CDS YP_002809219.1 227080668 7771729 complement(473557..473847) 1 NC_012578.1 hypothetical protein 473847 7771729 VCM66_0443 Vibrio cholerae M66-2 hypothetical protein YP_002809219.1 473557 R 579112 CDS YP_002809220.1 227080669 7771730 complement(473847..474404) 1 NC_012578.1 hypothetical protein 474404 7771730 VCM66_0444 Vibrio cholerae M66-2 hypothetical protein YP_002809220.1 473847 R 579112 CDS YP_002809221.1 227080670 7771731 complement(474458..475276) 1 NC_012578.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 475276 proC 7771731 proC Vibrio cholerae M66-2 pyrroline-5-carboxylate reductase YP_002809221.1 474458 R 579112 CDS YP_002809222.1 227080671 7771732 complement(475329..476039) 1 NC_012578.1 hypothetical protein 476039 7771732 VCM66_0446 Vibrio cholerae M66-2 hypothetical protein YP_002809222.1 475329 R 579112 CDS YP_002809223.1 227080672 7771733 476065..477102 1 NC_012578.1 twitching motility protein PilT 477102 pilT-1 7771733 pilT-1 Vibrio cholerae M66-2 twitching motility protein PilT YP_002809223.1 476065 D 579112 CDS YP_002809224.1 227080673 7771734 477117..478223 1 NC_012578.1 twitching motility protein PilT 478223 pilT-2 7771734 pilT-2 Vibrio cholerae M66-2 twitching motility protein PilT YP_002809224.1 477117 D 579112 CDS YP_002809225.1 227080674 7771735 478335..479138 1 NC_012578.1 LuxR family transcriptional regulator 479138 7771735 VCM66_0449 Vibrio cholerae M66-2 LuxR family transcriptional regulator YP_002809225.1 478335 D 579112 CDS YP_002809226.1 227080675 7771736 479223..480527 1 NC_012578.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 480527 tyrS-1 7771736 tyrS-1 Vibrio cholerae M66-2 tyrosyl-tRNA synthetase YP_002809226.1 479223 D 579112 CDS YP_002809227.1 227080676 7771737 complement(480565..480987) 1 NC_012578.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 480987 7771737 VCM66_0451 Vibrio cholerae M66-2 Holliday junction resolvase-like protein YP_002809227.1 480565 R 579112 CDS YP_002809228.1 227080677 7771738 complement(481068..481670) 1 NC_012578.1 hypothetical protein 481670 7771738 VCM66_0452 Vibrio cholerae M66-2 hypothetical protein YP_002809228.1 481068 R 579112 CDS YP_002809229.1 227080678 7771739 complement(481667..482623) 1 NC_012578.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 482623 gshB 7771739 gshB Vibrio cholerae M66-2 glutathione synthetase YP_002809229.1 481667 R 579112 CDS YP_002809230.1 227080679 7771740 complement(482637..483368) 1 NC_012578.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 483368 7771740 VCM66_0454 Vibrio cholerae M66-2 16S ribosomal RNA methyltransferase RsmE YP_002809230.1 482637 R 579112 CDS YP_002809231.1 227080680 7771741 complement(483506..484201) 1 NC_012578.1 extracellular deoxyribonuclease 484201 dns 7771741 dns Vibrio cholerae M66-2 extracellular deoxyribonuclease YP_002809231.1 483506 R 579112 CDS YP_002809232.1 227080681 7771742 complement(484329..484817) 1 NC_012578.1 hypothetical protein 484817 7771742 VCM66_0456 Vibrio cholerae M66-2 hypothetical protein YP_002809232.1 484329 R 579112 CDS YP_002809233.1 227080682 7771743 complement(484939..486096) 1 NC_012578.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 486096 metK 7771743 metK Vibrio cholerae M66-2 S-adenosylmethionine synthetase YP_002809233.1 484939 R 579112 CDS YP_002809234.1 227080683 7771744 486374..488458 1 NC_012578.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 488458 tktA-1 7771744 tktA-1 Vibrio cholerae M66-2 transketolase YP_002809234.1 486374 D 579112 CDS YP_002809235.1 227080684 7771745 complement(488530..489426) 1 NC_012578.1 iron-regulated virulence regulatory protein IrgB 489426 irgB 7771745 irgB Vibrio cholerae M66-2 iron-regulated virulence regulatory protein IrgB YP_002809235.1 488530 R 579112 CDS YP_002809236.1 227080685 7771746 489571..491529 1 NC_012578.1 IrgA; binds ferric enterobactin; irgA gene expression is repressed by Fur and induced by the divergently transcribed upstream gene irgB; outer membrane protein; involved in iron metabolism; enterobactin receptor protein 491529 irgA 7771746 irgA Vibrio cholerae M66-2 enterobactin receptor protein YP_002809236.1 489571 D 579112 CDS YP_002809237.1 227080686 7771747 491549..492706 1 NC_012578.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 492706 epd 7771747 epd Vibrio cholerae M66-2 erythrose 4-phosphate dehydrogenase YP_002809237.1 491549 D 579112 CDS YP_002809238.1 227080687 7771748 492840..494018 1 NC_012578.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 494018 pgk 7771748 pgk Vibrio cholerae M66-2 phosphoglycerate kinase YP_002809238.1 492840 D 579112 CDS YP_002809239.1 227080688 7771749 494174..495250 1 NC_012578.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 495250 fbaA 7771749 fbaA Vibrio cholerae M66-2 fructose-bisphosphate aldolase YP_002809239.1 494174 D 579112 CDS YP_002809240.1 227080689 7771750 495438..495533 1 NC_012578.1 hypothetical protein 495533 7771750 VCM66_0464 Vibrio cholerae M66-2 hypothetical protein YP_002809240.1 495438 D 579112 CDS YP_002809241.1 227080690 7771751 495546..496409 1 NC_012578.1 Small-conductance mechanosensitive channel 496409 7771751 VCM66_0465 Vibrio cholerae M66-2 Small-conductance mechanosensitive channel YP_002809241.1 495546 D 579112 CDS YP_002809242.1 227080691 7771752 complement(496473..497108) 1 NC_012578.1 LysE/YggA family protein 497108 7771752 VCM66_0466 Vibrio cholerae M66-2 LysE/YggA family protein YP_002809242.1 496473 R 579112 CDS YP_002809243.1 227080692 7771753 497273..498169 1 NC_012578.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 498169 iciA 7771753 iciA Vibrio cholerae M66-2 chromosome replication initiation inhibitor protein YP_002809243.1 497273 D 579112 CDS YP_002809244.1 227080693 7771754 498249..498965 1 NC_012578.1 hypothetical protein 498965 7771754 VCM66_0468 Vibrio cholerae M66-2 hypothetical protein YP_002809244.1 498249 D 579112 CDS YP_002809245.1 227080694 7771755 499298..499429 1 NC_012578.1 hypothetical protein 499429 7771755 VCM66_0469 Vibrio cholerae M66-2 hypothetical protein YP_002809245.1 499298 D 579112 CDS YP_002809246.1 227080695 7771756 complement(499501..500913) 1 NC_012578.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 500913 pykF 7771756 pykF Vibrio cholerae M66-2 pyruvate kinase YP_002809246.1 499501 R 579112 CDS YP_002809247.1 227080696 7771757 501329..502111 1 NC_012578.1 DeoR family transcriptional regulator 502111 7771757 VCM66_0471 Vibrio cholerae M66-2 DeoR family transcriptional regulator YP_002809247.1 501329 D 579112 CDS YP_002809248.1 227080697 7771758 502174..504006 1 NC_012578.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 504006 glmS 7771758 glmS Vibrio cholerae M66-2 glucosamine--fructose-6-phosphate aminotransferase YP_002809248.1 502174 D 579112 CDS YP_002809249.1 227080698 7771759 complement(504067..505146) 1 NC_012578.1 putative extracellular solute-binding protein 505146 7771759 VCM66_0473 Vibrio cholerae M66-2 putative extracellular solute-binding protein YP_002809249.1 504067 R 579112 CDS YP_002809250.1 227080699 7771760 complement(505403..507163) 1 NC_012578.1 putative hemolysin 507163 7771760 VCM66_0474 Vibrio cholerae M66-2 putative hemolysin YP_002809250.1 505403 R 579112 CDS YP_002809251.1 227080700 7774054 complement(507852..509729) 1 NC_012578.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 509729 rpoD 7774054 rpoD Vibrio cholerae M66-2 RNA polymerase sigma factor RpoD YP_002809251.1 507852 R 579112 CDS YP_002809252.1 227080701 7771762 complement(509828..511591) 1 NC_012578.1 synthesizes RNA primers at the replication forks; DNA primase 511591 dnaG 7771762 dnaG Vibrio cholerae M66-2 DNA primase YP_002809252.1 509828 R 579112 CDS YP_002809253.1 227080702 7771763 complement(511681..512124) 1 NC_012578.1 hypothetical protein 512124 7771763 VCM66_0477 Vibrio cholerae M66-2 hypothetical protein YP_002809253.1 511681 R 579112 CDS YP_002809254.1 227080703 7771764 complement(512154..512369) 1 NC_012578.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 512369 rpsU 7771764 rpsU Vibrio cholerae M66-2 30S ribosomal protein S21 YP_002809254.1 512154 R 579112 CDS YP_002809255.1 227080704 7771765 512610..513629 1 NC_012578.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 513629 gcp 7771765 gcp Vibrio cholerae M66-2 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002809255.1 512610 D 579112 CDS YP_002809256.1 227080705 7771766 513783..514595 1 NC_012578.1 putative beta-ketoadipate enol-lactone hydrolase 514595 7771766 VCM66_0480 Vibrio cholerae M66-2 putative beta-ketoadipate enol-lactone hydrolase YP_002809256.1 513783 D 579112 CDS YP_002809257.1 227080706 7771767 complement(514644..515270) 1 NC_012578.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 515270 7771767 VCM66_0481 Vibrio cholerae M66-2 putative glycerol-3-phosphate acyltransferase PlsY YP_002809257.1 514644 R 579112 CDS YP_002809258.1 227080707 7771768 515423..515812 1 NC_012578.1 putative dihydroneopterin aldolase FolB 515812 7771768 VCM66_0482 Vibrio cholerae M66-2 putative dihydroneopterin aldolase FolB YP_002809258.1 515423 D 579112 CDS YP_002809259.1 227080708 7771769 515728..516315 1 NC_012578.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 516315 folK-1 7771769 folK-1 Vibrio cholerae M66-2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002809259.1 515728 D 579112 CDS YP_002809260.1 227080709 7771770 516312..517115 1 NC_012578.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 517115 7771770 VCM66_0484 Vibrio cholerae M66-2 UDP pyrophosphate phosphatase YP_002809260.1 516312 D 579112 CDS YP_002809261.1 227080710 7771771 517224..517514 1 NC_012578.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 517514 ftsB 7771771 ftsB Vibrio cholerae M66-2 cell division protein FtsB YP_002809261.1 517224 D 579112 CDS YP_002809262.1 227080711 7771772 517511..518209 1 NC_012578.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 518209 ispD 7771772 ispD Vibrio cholerae M66-2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002809262.1 517511 D 579112 CDS YP_002809263.1 227080712 7771773 518206..518682 1 NC_012578.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 518682 ispF 7771773 ispF Vibrio cholerae M66-2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002809263.1 518206 D 579112 CDS YP_002809264.1 227080713 7771774 518712..519797 1 NC_012578.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 519797 truD 7771774 truD Vibrio cholerae M66-2 tRNA pseudouridine synthase D YP_002809264.1 518712 D 579112 CDS YP_002809265.1 227080714 7771775 519760..520551 1 NC_012578.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 520551 surE 7771775 surE Vibrio cholerae M66-2 stationary phase survival protein SurE YP_002809265.1 519760 D 579112 CDS YP_002809266.1 227080715 7771776 520544..521170 1 NC_012578.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 521170 pcm 7771776 pcm Vibrio cholerae M66-2 protein-L-isoaspartate O-methyltransferase YP_002809266.1 520544 D 579112 CDS YP_002809267.1 227080716 7771777 521170..522105 1 NC_012578.1 lipoprotein NlpD 522105 nlpD 7771777 nlpD Vibrio cholerae M66-2 lipoprotein NlpD YP_002809267.1 521170 D 579112 CDS YP_002809268.1 227080717 7771778 522179..523186 1 NC_012578.1 RNA polymerase sigma factor RpoS 523186 rpoS 7771778 rpoS Vibrio cholerae M66-2 RNA polymerase sigma factor RpoS YP_002809268.1 522179 D 579112 CDS YP_002809269.1 227080718 7771779 complement(523279..525867) 1 NC_012578.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 525867 mutS 7771779 mutS Vibrio cholerae M66-2 DNA mismatch repair protein MutS YP_002809269.1 523279 R 579112 CDS YP_002809270.1 227080719 7771780 525874..525975 1 NC_012578.1 hypothetical protein 525975 7771780 VCM66_0494 Vibrio cholerae M66-2 hypothetical protein YP_002809270.1 525874 D 579112 CDS YP_002809271.1 227080720 7771781 complement(526135..527022) 1 NC_012578.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 527022 cysM 7771781 cysM Vibrio cholerae M66-2 cysteine synthase B YP_002809271.1 526135 R 579112 CDS YP_002809272.1 227080721 7771782 527406..528407 1 NC_012578.1 thiosulfate ABC transporter periplasmic thiosulfate-binding protein 528407 cysP 7771782 cysP Vibrio cholerae M66-2 thiosulfate ABC transporter periplasmic thiosulfate-binding protein YP_002809272.1 527406 D 579112 CDS YP_002809273.1 227080722 7771783 528484..529335 1 NC_012578.1 sulfate ABC transporter permease 529335 cysT 7771783 cysT Vibrio cholerae M66-2 sulfate ABC transporter permease YP_002809273.1 528484 D 579112 CDS YP_002809274.1 227080723 7771784 529346..530209 1 NC_012578.1 sulfate ABC transporter permease 530209 cysW 7771784 cysW Vibrio cholerae M66-2 sulfate ABC transporter permease YP_002809274.1 529346 D 579112 CDS YP_002809275.1 227080724 7771785 530206..531336 1 NC_012578.1 sulfate ABC transporter ATP-binding protein 531336 cysA 7771785 cysA Vibrio cholerae M66-2 sulfate ABC transporter ATP-binding protein YP_002809275.1 530206 D 579112 CDS YP_002809276.1 227080725 7771786 531503..532009 1 NC_012578.1 CinA-like protein 532009 7771786 VCM66_0500 Vibrio cholerae M66-2 CinA-like protein YP_002809276.1 531503 D 579112 CDS YP_002809277.1 227080726 7771787 531969..533207 1 NC_012578.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 533207 recA 7771787 recA Vibrio cholerae M66-2 recombinase A YP_002809277.1 531969 D 579112 CDS YP_002809278.1 227080727 7771788 533340..533798 1 NC_012578.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 533798 recX 7771788 recX Vibrio cholerae M66-2 recombination regulator RecX YP_002809278.1 533340 D 579112 CDS YP_002809279.1 227080728 7771789 533971..536553 1 NC_012578.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 536553 alaS 7771789 alaS Vibrio cholerae M66-2 alanyl-tRNA synthetase YP_002809279.1 533971 D 579112 CDS YP_002809280.1 227080729 7771790 536585..536704 1 NC_012578.1 hypothetical protein 536704 7771790 VCM66_0504 Vibrio cholerae M66-2 hypothetical protein YP_002809280.1 536585 D 579112 CDS YP_002809281.1 227080730 7771791 536757..537944 1 NC_012578.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; aspartate kinase 537944 7771791 VCM66_0505 Vibrio cholerae M66-2 aspartate kinase YP_002809281.1 536757 D 579112 CDS YP_002809282.1 227080731 7771792 538036..538233 1 NC_012578.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 538233 csrA 7771792 csrA Vibrio cholerae M66-2 carbon storage regulator YP_002809282.1 538036 D 579112 CDS YP_002809283.1 227080732 7774001 539711..540064 1 NC_012578.1 oxaloacetate decarboxylase subunit gamma 540064 7774001 VCM66_0507 Vibrio cholerae M66-2 oxaloacetate decarboxylase subunit gamma YP_002809283.1 539711 D 579112 CDS YP_002809284.1 227080733 7771794 540093..541886 1 NC_012578.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 541886 oadA-1 7771794 oadA-1 Vibrio cholerae M66-2 oxaloacetate decarboxylase YP_002809284.1 540093 D 579112 CDS YP_002809285.1 227080734 7771795 541896..543026 1 NC_012578.1 oxaloacetate decarboxylase subunit beta 543026 oadB-1 7771795 oadB-1 Vibrio cholerae M66-2 oxaloacetate decarboxylase subunit beta YP_002809285.1 541896 D 579112 CDS YP_002809286.1 227080735 7771796 543086..544099 1 NC_012578.1 quinone oxidoreductase 544099 7771796 VCM66_0510 Vibrio cholerae M66-2 quinone oxidoreductase YP_002809286.1 543086 D 579112 CDS YP_002809287.1 227080736 7771797 544093..544554 1 NC_012578.1 putative Inner membrane protein 544554 7771797 VCM66_0511 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809287.1 544093 D 579112 CDS YP_002809288.1 227080737 7771798 544561..547419 1 NC_012578.1 protease, insulinase family/protease, insulinase family 547419 7771798 VCM66_0512 Vibrio cholerae M66-2 protease, insulinase family/protease, insulinase family YP_002809288.1 544561 D 579112 CDS YP_002809289.1 227080738 7771799 complement(547409..547510) 1 NC_012578.1 hypothetical protein 547510 7771799 VCM66_0513 Vibrio cholerae M66-2 hypothetical protein YP_002809289.1 547409 R 579112 CDS YP_002809290.1 227080739 7771800 547531..549105 1 NC_012578.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 549105 gshA 7771800 gshA Vibrio cholerae M66-2 glutamate--cysteine ligase YP_002809290.1 547531 D 579112 CDS YP_002809291.1 227080740 7771801 549154..549672 1 NC_012578.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 549672 luxS 7771801 luxS Vibrio cholerae M66-2 S-ribosylhomocysteinase YP_002809291.1 549154 D 579112 CDS YP_002809292.1 227080741 7771802 complement(549742..551022) 1 NC_012578.1 putative hemolysin 551022 7771802 VCM66_0516 Vibrio cholerae M66-2 putative hemolysin YP_002809292.1 549742 R 579112 CDS YP_002809293.1 227080742 7771803 complement(551105..551908) 1 NC_012578.1 putative Inner membrane protein 551908 7771803 VCM66_0517 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809293.1 551105 R 579112 CDS YP_002809294.1 227080743 7771804 552112..553497 1 NC_012578.1 signal recognition particle protein 553497 ffh 7771804 ffh Vibrio cholerae M66-2 signal recognition particle protein YP_002809294.1 552112 D 579112 CDS YP_002809295.1 227080744 7771805 553733..553981 1 NC_012578.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 553981 rpsP 7771805 rpsP Vibrio cholerae M66-2 30S ribosomal protein S16 YP_002809295.1 553733 D 579112 CDS YP_002809296.1 227080745 7771806 554009..554563 1 NC_012578.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 554563 rimM 7771806 rimM Vibrio cholerae M66-2 16S rRNA-processing protein RimM YP_002809296.1 554009 D 579112 CDS YP_002809297.1 227080746 7771807 554591..555334 1 NC_012578.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 555334 trmD 7771807 trmD Vibrio cholerae M66-2 tRNA (guanine-N(1)-)-methyltransferase YP_002809297.1 554591 D 579112 CDS YP_002809298.1 227080747 7771808 555376..555729 1 NC_012578.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 555729 rplS 7771808 rplS Vibrio cholerae M66-2 50S ribosomal protein L19 YP_002809298.1 555376 D 579112 CDS YP_002809299.1 227080748 7771809 complement(555850..556908) 1 NC_012578.1 protease DegS 556908 degS 7771809 degS Vibrio cholerae M66-2 protease DegS YP_002809299.1 555850 R 579112 CDS YP_002809300.1 227080749 7771810 complement(557085..558455) 1 NC_012578.1 protease DO 558455 htrA 7771810 htrA Vibrio cholerae M66-2 protease DO YP_002809300.1 557085 R 579112 CDS YP_002809301.1 227080750 7771811 complement(558584..559021) 1 NC_012578.1 cytochrome d ubiquinol oxidase subunit III 559021 7771811 VCM66_0525 Vibrio cholerae M66-2 cytochrome d ubiquinol oxidase subunit III YP_002809301.1 558584 R 579112 CDS YP_002809302.1 227080751 7771812 559175..560278 1 NC_012578.1 hypothetical protein 560278 7771812 VCM66_0526 Vibrio cholerae M66-2 hypothetical protein YP_002809302.1 559175 D 579112 CDS YP_002809303.1 227080752 7771813 complement(560208..560417) 1 NC_012578.1 hypothetical protein 560417 7771813 VCM66_0527 Vibrio cholerae M66-2 hypothetical protein YP_002809303.1 560208 R 579112 CDS YP_002809304.1 227080753 7771814 560502..560930 1 NC_012578.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 560930 rplM 7771814 rplM Vibrio cholerae M66-2 50S ribosomal protein L13 YP_002809304.1 560502 D 579112 CDS YP_002809305.1 227080754 7771815 560946..561338 1 NC_012578.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 561338 rpsI 7771815 rpsI Vibrio cholerae M66-2 30S ribosomal protein S9 YP_002809305.1 560946 D 579112 CDS YP_002809306.1 227080755 7771816 561348..561473 1 NC_012578.1 hypothetical protein 561473 7771816 VCM66_0530 Vibrio cholerae M66-2 hypothetical protein YP_002809306.1 561348 D 579112 CDS YP_002809307.1 227080756 7771817 561666..562259 1 NC_012578.1 ubiquinol--cytochrome c reductase, iron-sulfur subunit 562259 petA 7771817 petA Vibrio cholerae M66-2 ubiquinol--cytochrome c reductase, iron-sulfur subunit YP_002809307.1 561666 D 579112 CDS YP_002809308.1 227080757 7771818 562259..563524 1 NC_012578.1 ubiquinol--cytochrome c reductase, cytochrome B 563524 petB 7771818 petB Vibrio cholerae M66-2 ubiquinol--cytochrome c reductase, cytochrome B YP_002809308.1 562259 D 579112 CDS YP_002809309.1 227080758 7771819 563521..564258 1 NC_012578.1 ubiquinol--cytochrome c reductase, cytochrome c1 564258 petC 7771819 petC Vibrio cholerae M66-2 ubiquinol--cytochrome c reductase, cytochrome c1 YP_002809309.1 563521 D 579112 CDS YP_002809310.1 227080759 7771820 564358..564993 1 NC_012578.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 564993 sspA 7771820 sspA Vibrio cholerae M66-2 stringent starvation protein A YP_002809310.1 564358 D 579112 CDS YP_002809311.1 227080760 7771821 564993..565469 1 NC_012578.1 ClpXP protease specificity-enhancing factor 565469 sspB 7771821 sspB Vibrio cholerae M66-2 ClpXP protease specificity-enhancing factor YP_002809311.1 564993 D 579112 CDS YP_002809312.1 227080761 7771822 complement(565537..566106) 1 NC_012578.1 putative hemolysin 566106 7771822 VCM66_0536 Vibrio cholerae M66-2 putative hemolysin YP_002809312.1 565537 R 579112 CDS YP_002809313.1 227080762 7771823 complement(566109..566699) 1 NC_012578.1 putative phosphoheptose isomerase 566699 7771823 VCM66_0537 Vibrio cholerae M66-2 putative phosphoheptose isomerase YP_002809313.1 566109 R 579112 CDS YP_002809314.1 227080763 7771824 complement(566703..567071) 1 NC_012578.1 hypothetical protein 567071 7771824 VCM66_0538 Vibrio cholerae M66-2 hypothetical protein YP_002809314.1 566703 R 579112 CDS YP_002809315.1 227080764 7771825 complement(567058..569019) 1 NC_012578.1 putative lipoprotein 569019 7771825 VCM66_0539 Vibrio cholerae M66-2 putative lipoprotein YP_002809315.1 567058 R 579112 CDS YP_002809316.1 227080765 7771826 568933..569799 1 NC_012578.1 hypothetical protein 569799 7771826 VCM66_0540 Vibrio cholerae M66-2 hypothetical protein YP_002809316.1 568933 D 579112 CDS YP_002809317.1 227080766 7771827 complement(569877..570623) 1 NC_012578.1 hemagglutinin/protease regulatory protein 570623 hapR 7771827 hapR Vibrio cholerae M66-2 hemagglutinin/protease regulatory protein YP_002809317.1 569877 R 579112 CDS YP_002809318.1 227080767 7771828 complement(570838..570954) 1 NC_012578.1 hypothetical protein 570954 7771828 VCM66_0542 Vibrio cholerae M66-2 hypothetical protein YP_002809318.1 570838 R 579112 CDS YP_002809319.1 227080768 7771829 570919..571452 1 NC_012578.1 hypoxanthine phosphoribosyltransferase 571452 hpt 7771829 hpt Vibrio cholerae M66-2 hypoxanthine phosphoribosyltransferase YP_002809319.1 570919 D 579112 CDS YP_002809320.1 227080769 7771830 complement(571527..572195) 1 NC_012578.1 putative carbonic anhydrase 572195 7771830 VCM66_0544 Vibrio cholerae M66-2 putative carbonic anhydrase YP_002809320.1 571527 R 579112 CDS YP_002809321.1 227080770 7771831 572343..573989 1 NC_012578.1 sulfate permease family protein 573989 7771831 VCM66_0545 Vibrio cholerae M66-2 sulfate permease family protein YP_002809321.1 572343 D 579112 CDS YP_002809322.1 227080771 7771832 574097..574198 1 NC_012578.1 hypothetical protein 574198 7771832 VCM66_0546 Vibrio cholerae M66-2 hypothetical protein YP_002809322.1 574097 D 579112 CDS YP_002809323.1 227080772 7771833 574373..575290 1 NC_012578.1 ABC transporter ATP-binding protein 575290 7771833 VCM66_0547 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002809323.1 574373 D 579112 CDS YP_002809324.1 227080773 7771834 575296..576066 1 NC_012578.1 putative permease 576066 7771834 VCM66_0548 Vibrio cholerae M66-2 putative permease YP_002809324.1 575296 D 579112 CDS YP_002809325.1 227080774 7771835 complement(576130..577011) 1 NC_012578.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 577011 panC 7771835 panC Vibrio cholerae M66-2 pantoate--beta-alanine ligase YP_002809325.1 576130 R 579112 CDS YP_002809326.1 227080775 7771836 complement(577022..577816) 1 NC_012578.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 577816 panB 7771836 panB Vibrio cholerae M66-2 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002809326.1 577022 R 579112 CDS YP_002809327.1 227080776 7771837 complement(577819..578322) 1 NC_012578.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 578322 folK-2 7771837 folK-2 Vibrio cholerae M66-2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002809327.1 577819 R 579112 CDS YP_002809328.1 227080777 7771838 complement(578319..579692) 1 NC_012578.1 polyA polymerase 579692 pcnB 7771838 pcnB Vibrio cholerae M66-2 polyA polymerase YP_002809328.1 578319 R 579112 CDS YP_002809329.1 227080778 7771839 complement(579783..580673) 1 NC_012578.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 580673 7771839 VCM66_0553 Vibrio cholerae M66-2 glutamyl-Q tRNA(Asp) synthetase YP_002809329.1 579783 R 579112 CDS YP_002809330.1 227080779 7771840 complement(580747..581193) 1 NC_012578.1 dnaK suppressor protein 581193 dksA 7771840 dksA Vibrio cholerae M66-2 dnaK suppressor protein YP_002809330.1 580747 R 579112 CDS YP_002809331.1 227080780 7771841 complement(581318..582088) 1 NC_012578.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 582088 sfsA 7771841 sfsA Vibrio cholerae M66-2 sugar fermentation stimulation protein A YP_002809331.1 581318 R 579112 CDS YP_002809332.1 227080781 7771842 582076..582177 1 NC_012578.1 hypothetical protein 582177 7771842 VCM66_0556 Vibrio cholerae M66-2 hypothetical protein YP_002809332.1 582076 D 579112 CDS YP_002809333.1 227080782 7771843 582299..583651 1 NC_012578.1 hypothetical protein 583651 7771843 VCM66_0558 Vibrio cholerae M66-2 hypothetical protein YP_002809333.1 582299 D 579112 CDS YP_002809334.1 227080783 7773953 586209..588542 1 NC_012578.1 penicillin-binding protein 1B 588542 mrcB 7773953 mrcB Vibrio cholerae M66-2 penicillin-binding protein 1B YP_002809334.1 586209 D 579112 CDS YP_002809335.1 227080784 7771845 588779..591073 1 NC_012578.1 hypothetical protein 591073 7771845 VCM66_0561 Vibrio cholerae M66-2 hypothetical protein YP_002809335.1 588779 D 579112 CDS YP_002809336.1 227080785 7771846 591338..593935 1 NC_012578.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 593935 acnB 7771846 acnB Vibrio cholerae M66-2 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002809336.1 591338 D 579112 CDS YP_002809337.1 227080786 7771847 594090..594470 1 NC_012578.1 hypothetical protein 594470 7771847 VCM66_0563 Vibrio cholerae M66-2 hypothetical protein YP_002809337.1 594090 D 579112 CDS YP_002809338.1 227080787 7771848 594621..594986 1 NC_012578.1 nitrogen regulatory protein P-II 594986 glnB-1 7771848 glnB-1 Vibrio cholerae M66-2 nitrogen regulatory protein P-II YP_002809338.1 594621 D 579112 CDS YP_002809339.1 227080788 7771849 595008..596237 1 NC_012578.1 putative ammonium transporter 596237 7771849 VCM66_0565 Vibrio cholerae M66-2 putative ammonium transporter YP_002809339.1 595008 D 579112 CDS YP_002809340.1 227080789 7771850 596334..597392 1 NC_012578.1 iron(III) ABC transporter periplasmic iron-compound-binding protein 597392 fbpA 7771850 fbpA Vibrio cholerae M66-2 iron(III) ABC transporter periplasmic iron-compound-binding protein YP_002809340.1 596334 D 579112 CDS YP_002809341.1 227080790 7771851 597476..599101 1 NC_012578.1 iron(III) ABC transporter permease 599101 fbpB 7771851 fbpB Vibrio cholerae M66-2 iron(III) ABC transporter permease YP_002809341.1 597476 D 579112 CDS YP_002809342.1 227080791 7771852 599101..600132 1 NC_012578.1 iron(III) ABC transporter ATP-binding protein 600132 fbpC 7771852 fbpC Vibrio cholerae M66-2 iron(III) ABC transporter ATP-binding protein YP_002809342.1 599101 D 579112 CDS YP_002809343.1 227080792 7771853 complement(600263..601675) 1 NC_012578.1 putative phosphoglucomutase/phosphomannomutase 601675 7771853 VCM66_0569 Vibrio cholerae M66-2 putative phosphoglucomutase/phosphomannomutase YP_002809343.1 600263 R 579112 CDS YP_002809344.1 227080793 7771854 complement(601798..604203) 1 NC_012578.1 putative cellobiose/cellodextrin-phosphorylase 604203 7771854 VCM66_0570 Vibrio cholerae M66-2 putative cellobiose/cellodextrin-phosphorylase YP_002809344.1 601798 R 579112 CDS YP_002809345.1 227080794 7771855 complement(604322..606235) 1 NC_012578.1 beta-N-acetylhexosaminidase 606235 chb-1 7771855 chb-1 Vibrio cholerae M66-2 beta-N-acetylhexosaminidase YP_002809345.1 604322 R 579112 CDS YP_002809346.1 227080795 7771856 complement(606232..607209) 1 NC_012578.1 N-acetylglucosamine kinase 607209 7771856 VCM66_0572 Vibrio cholerae M66-2 N-acetylglucosamine kinase YP_002809346.1 606232 R 579112 CDS YP_002809347.1 227080796 7771857 complement(607113..608837) 1 NC_012578.1 endoglucanase-like protein 608837 7771857 VCM66_0573 Vibrio cholerae M66-2 endoglucanase-like protein YP_002809347.1 607113 R 579112 CDS YP_002809348.1 227080797 7771858 complement(608894..609889) 1 NC_012578.1 peptide ABC transporter ATP-binding protein 609889 7771858 VCM66_0574 Vibrio cholerae M66-2 peptide ABC transporter ATP-binding protein YP_002809348.1 608894 R 579112 CDS YP_002809349.1 227080798 7771859 complement(609932..610915) 1 NC_012578.1 peptide ABC transporter ATP-binding protein 610915 7771859 VCM66_0575 Vibrio cholerae M66-2 peptide ABC transporter ATP-binding protein YP_002809349.1 609932 R 579112 CDS YP_002809350.1 227080799 7771860 complement(610918..611943) 1 NC_012578.1 peptide ABC transporter permease 611943 7771860 VCM66_0576 Vibrio cholerae M66-2 peptide ABC transporter permease YP_002809350.1 610918 R 579112 CDS YP_002809351.1 227080800 7771861 complement(611946..612932) 1 NC_012578.1 peptide ABC transporter permease 612932 7771861 VCM66_0577 Vibrio cholerae M66-2 peptide ABC transporter permease YP_002809351.1 611946 R 579112 CDS YP_002809352.1 227080801 7771862 complement(613102..614772) 1 NC_012578.1 peptide ABC transporter substrate-binding protein 614772 7771862 VCM66_0578 Vibrio cholerae M66-2 peptide ABC transporter substrate-binding protein YP_002809352.1 613102 R 579112 CDS YP_002809353.1 227080802 7771863 615345..615734 1 NC_012578.1 hypothetical protein 615734 7771863 VCM66_0579 Vibrio cholerae M66-2 hypothetical protein YP_002809353.1 615345 D 579112 CDS YP_002809354.1 227080803 7771864 complement(615683..619216) 1 NC_012578.1 sensory box sensor histidine kinase/response regulator 619216 7771864 VCM66_0580 Vibrio cholerae M66-2 sensory box sensor histidine kinase/response regulator YP_002809354.1 615683 R 579112 CDS YP_002809355.1 227080804 7771865 complement(619280..620302) 1 NC_012578.1 Ribosomal RNA small subunit methyltransferase C 620302 7771865 VCM66_0581 Vibrio cholerae M66-2 Ribosomal RNA small subunit methyltransferase C YP_002809355.1 619280 R 579112 CDS YP_002809356.1 227080805 7771866 complement(620375..621460) 1 NC_012578.1 hypothetical protein 621460 7771866 VCM66_0582 Vibrio cholerae M66-2 hypothetical protein YP_002809356.1 620375 R 579112 CDS YP_002809357.1 227080806 7771867 621497..621652 1 NC_012578.1 hypothetical protein 621652 7771867 VCM66_0583 Vibrio cholerae M66-2 hypothetical protein YP_002809357.1 621497 D 579112 CDS YP_002809358.1 227080807 7771868 complement(621714..623012) 1 NC_012578.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 623012 hemL 7771868 hemL Vibrio cholerae M66-2 glutamate-1-semialdehyde aminotransferase YP_002809358.1 621714 R 579112 CDS YP_002809359.1 227080808 7771869 623296..623637 1 NC_012578.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 623637 7771869 VCM66_0585 Vibrio cholerae M66-2 iron-sulfur cluster insertion protein ErpA YP_002809359.1 623296 D 579112 CDS YP_002809360.1 227080809 7771870 623735..624835 1 NC_012578.1 Nodulation protein nolF 624835 7771870 VCM66_0586 Vibrio cholerae M66-2 Nodulation protein nolF YP_002809360.1 623735 D 579112 CDS YP_002809361.1 227080810 7771871 624744..627965 1 NC_012578.1 putative multidrug resistance protein 627965 7771871 VCM66_0587 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002809361.1 624744 D 579112 CDS YP_002809362.1 227080811 7771872 complement(628047..629348) 1 NC_012578.1 hypothetical protein 629348 7771872 VCM66_0588 Vibrio cholerae M66-2 hypothetical protein YP_002809362.1 628047 R 579112 CDS YP_002809363.1 227080812 7771873 629479..630666 1 NC_012578.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 630666 tyrS-2 7771873 tyrS-2 Vibrio cholerae M66-2 tyrosyl-tRNA synthetase YP_002809363.1 629479 D 579112 CDS YP_002809364.1 227080813 7771874 complement(630734..632197) 1 NC_012578.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 632197 dacB 7771874 dacB Vibrio cholerae M66-2 D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_002809364.1 630734 R 579112 CDS YP_002809365.1 227080814 7771875 complement(632277..633329) 1 NC_012578.1 outer membrane protein OmpU 633329 ompU 7771875 ompU Vibrio cholerae M66-2 outer membrane protein OmpU YP_002809365.1 632277 R 579112 CDS YP_002809366.1 227080815 7771876 633853..634329 1 NC_012578.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 634329 greA 7771876 greA Vibrio cholerae M66-2 transcription elongation factor GreA YP_002809366.1 633853 D 579112 CDS YP_002809367.1 227080816 7771877 complement(634406..634702) 1 NC_012578.1 hypothetical protein 634702 7771877 VCM66_0593 Vibrio cholerae M66-2 hypothetical protein YP_002809367.1 634406 R 579112 CDS YP_002809368.1 227080817 7771878 634822..635451 1 NC_012578.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 635451 rrmJ 7771878 rrmJ Vibrio cholerae M66-2 23S rRNA methyltransferase J YP_002809368.1 634822 D 579112 CDS YP_002809369.1 227080818 7771879 635552..637507 1 NC_012578.1 cell division protein FtsH 637507 ftsH 7771879 ftsH Vibrio cholerae M66-2 cell division protein FtsH YP_002809369.1 635552 D 579112 CDS YP_002809370.1 227080819 7771880 637574..638410 1 NC_012578.1 dihydropteroate synthase 638410 folP 7771880 folP Vibrio cholerae M66-2 dihydropteroate synthase YP_002809370.1 637574 D 579112 CDS YP_002809371.1 227080820 7771881 638436..639776 1 NC_012578.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 639776 glmM 7771881 glmM Vibrio cholerae M66-2 phosphoglucosamine mutase YP_002809371.1 638436 D 579112 CDS YP_002809372.1 227080821 7771882 640033..640368 1 NC_012578.1 preprotein translocase subunit SecG 640368 secG 7771882 secG Vibrio cholerae M66-2 preprotein translocase subunit SecG YP_002809372.1 640033 D 579112 CDS YP_002809373.1 227080822 7774050 640799..641254 1 NC_012578.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 641254 7774050 VCM66_0599 Vibrio cholerae M66-2 hypothetical protein YP_002809373.1 640799 D 579112 CDS YP_002809374.1 227080823 7771884 641273..642760 1 NC_012578.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 642760 nusA 7771884 nusA Vibrio cholerae M66-2 transcription elongation factor NusA YP_002809374.1 641273 D 579112 CDS YP_002809375.1 227080824 7771885 642785..645481 1 NC_012578.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 645481 infB 7771885 infB Vibrio cholerae M66-2 translation initiation factor IF-2 YP_002809375.1 642785 D 579112 CDS YP_002809376.1 227080825 7771886 645571..645981 1 NC_012578.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 645981 rbfA 7771886 rbfA Vibrio cholerae M66-2 ribosome-binding factor A YP_002809376.1 645571 D 579112 CDS YP_002809377.1 227080826 7771887 645981..646919 1 NC_012578.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 646919 truB 7771887 truB Vibrio cholerae M66-2 tRNA pseudouridine synthase B YP_002809377.1 645981 D 579112 CDS YP_002809378.1 227080827 7771888 647061..647330 1 NC_012578.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 647330 rpsO 7771888 rpsO Vibrio cholerae M66-2 30S ribosomal protein S15 YP_002809378.1 647061 D 579112 CDS YP_002809379.1 227080828 7771889 647693..649822 1 NC_012578.1 polynucleotide phosphorylase/polyadenylase 649822 pnp 7771889 pnp Vibrio cholerae M66-2 polynucleotide phosphorylase/polyadenylase YP_002809379.1 647693 D 579112 CDS YP_002809380.1 227080829 7771890 649938..650849 1 NC_012578.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 650849 7771890 VCM66_0606 Vibrio cholerae M66-2 lipoprotein NlpI YP_002809380.1 649938 D 579112 CDS YP_002809381.1 227080830 7771891 650936..651355 1 NC_012578.1 MarR family transcriptional regulator 651355 7771891 VCM66_0607 Vibrio cholerae M66-2 MarR family transcriptional regulator YP_002809381.1 650936 D 579112 CDS YP_002809382.1 227080831 7771892 651402..652739 1 NC_012578.1 sodium/drug antiporter; functions as a Na(+)-driven Na(+)/drug antiporter; member of multidrug and toxic compound extrusion (MATE) family; extrudes acriflavines and other compounds by utilizing the sodium gradient; multidrug efflux pump VmrA 652739 vmrA 7771892 vmrA Vibrio cholerae M66-2 multidrug efflux pump VmrA YP_002809382.1 651402 D 579112 CDS YP_002809383.1 227080832 7771893 complement(652792..653757) 1 NC_012578.1 hypothetical protein 653757 7771893 VCM66_0609 Vibrio cholerae M66-2 hypothetical protein YP_002809383.1 652792 R 579112 CDS YP_002809384.1 227080833 7771894 complement(653682..654695) 1 NC_012578.1 putative protease 654695 7771894 VCM66_0610 Vibrio cholerae M66-2 putative protease YP_002809384.1 653682 R 579112 CDS YP_002809385.1 227080834 7771895 complement(654803..656857) 1 NC_012578.1 c-di-GMP phosphodiesterase A-like protein 656857 7771895 VCM66_0611 Vibrio cholerae M66-2 c-di-GMP phosphodiesterase A-like protein YP_002809385.1 654803 R 579112 CDS YP_002809386.1 227080835 7771896 657090..657617 1 NC_012578.1 hypothetical protein 657617 7771896 VCM66_0612 Vibrio cholerae M66-2 hypothetical protein YP_002809386.1 657090 D 579112 CDS YP_002809387.1 227080836 7771897 657553..658104 1 NC_012578.1 putative acetyltransferase 658104 7771897 VCM66_0613 Vibrio cholerae M66-2 putative acetyltransferase YP_002809387.1 657553 D 579112 CDS YP_002809388.1 227080837 7771898 658215..658622 1 NC_012578.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 658622 holD 7771898 holD Vibrio cholerae M66-2 DNA polymerase III subunit psi YP_002809388.1 658215 D 579112 CDS YP_002809389.1 227080838 7771899 658583..659068 1 NC_012578.1 ribosomal-protein-alanine acetyltransferase 659068 rimI 7771899 rimI Vibrio cholerae M66-2 ribosomal-protein-alanine acetyltransferase YP_002809389.1 658583 D 579112 CDS YP_002809390.1 227080839 7771900 complement(659057..661114) 1 NC_012578.1 c-di-GMP phosphodiesterase A-like protein 661114 7771900 VCM66_0616 Vibrio cholerae M66-2 c-di-GMP phosphodiesterase A-like protein YP_002809390.1 659057 R 579112 CDS YP_002809391.1 227080840 7771901 661318..662913 1 NC_012578.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 662913 prfC 7771901 prfC Vibrio cholerae M66-2 peptide chain release factor 3 YP_002809391.1 661318 D 579112 CDS YP_002809392.1 227080841 7771902 complement(663035..664306) 1 NC_012578.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 664306 srmB 7771902 srmB Vibrio cholerae M66-2 ATP-dependent RNA helicase SrmB YP_002809392.1 663035 R 579112 CDS YP_002809393.1 227080842 7771903 complement(664394..665116) 1 NC_012578.1 hypothetical protein 665116 7771903 VCM66_0619 Vibrio cholerae M66-2 hypothetical protein YP_002809393.1 664394 R 579112 CDS YP_002809394.1 227080843 7771904 665425..666738 1 NC_012578.1 branched chain amino acid transport system II carrier protein 666738 brnQ 7771904 brnQ Vibrio cholerae M66-2 branched chain amino acid transport system II carrier protein YP_002809394.1 665425 D 579112 CDS YP_002809395.1 227080844 7771905 667107..668006 1 NC_012578.1 peptide chain release factor 2 668006 prfB 7771905 prfB Vibrio cholerae M66-2 peptide chain release factor 2 YP_002809395.1 667107 D 579112 CDS YP_002809396.1 227080845 7771906 668031..669569 1 NC_012578.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 669569 lysS 7771906 lysS Vibrio cholerae M66-2 lysyl-tRNA synthetase YP_002809396.1 668031 D 579112 CDS YP_002809397.1 227080846 7771907 669843..671177 1 NC_012578.1 sigma-54 dependent transcriptional regulator 671177 7771907 VCM66_0623 Vibrio cholerae M66-2 sigma-54 dependent transcriptional regulator YP_002809397.1 669843 D 579112 CDS YP_002809398.1 227080847 7771908 671692..672006 1 NC_012578.1 hypothetical protein 672006 7771908 VCM66_0624 Vibrio cholerae M66-2 hypothetical protein YP_002809398.1 671692 D 579112 CDS YP_002809399.1 227080848 7771909 complement(672044..673102) 1 NC_012578.1 oxidoreductase Tas, aldo/keto reductase family 673102 7771909 VCM66_0625 Vibrio cholerae M66-2 oxidoreductase Tas, aldo/keto reductase family YP_002809399.1 672044 R 579112 CDS YP_002809400.1 227080849 7771910 complement(673295..673960) 1 NC_012578.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 673960 mutH 7771910 mutH Vibrio cholerae M66-2 DNA mismatch repair protein YP_002809400.1 673295 R 579112 CDS YP_002809401.1 227080850 7771911 complement(674347..674439) 1 NC_012578.1 hypothetical protein 674439 7771911 VCM66_0627 Vibrio cholerae M66-2 hypothetical protein YP_002809401.1 674347 R 579112 CDS YP_002809402.1 227080851 7771912 674422..674568 1 NC_012578.1 hypothetical protein 674568 7771912 VCM66_0628 Vibrio cholerae M66-2 hypothetical protein YP_002809402.1 674422 D 579112 CDS YP_002809403.1 227080852 7771913 674528..675109 1 NC_012578.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 675109 7771913 VCM66_0629 Vibrio cholerae M66-2 dinucleoside polyphosphate hydrolase YP_002809403.1 674528 D 579112 CDS YP_002809404.1 227080853 7771914 675112..677358 1 NC_012578.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 677358 ptsP 7771914 ptsP Vibrio cholerae M66-2 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_002809404.1 675112 D 579112 CDS YP_002809405.1 227080854 7771915 677368..678162 1 NC_012578.1 hypothetical protein 678162 7771915 VCM66_0631 Vibrio cholerae M66-2 hypothetical protein YP_002809405.1 677368 D 579112 CDS YP_002809406.1 227080855 7771916 678191..679006 1 NC_012578.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 679006 lgt 7771916 lgt Vibrio cholerae M66-2 prolipoprotein diacylglyceryl transferase YP_002809406.1 678191 D 579112 CDS YP_002809407.1 227080856 7771917 679016..679867 1 NC_012578.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 679867 thyA 7771917 thyA Vibrio cholerae M66-2 thymidylate synthase YP_002809407.1 679016 D 579112 CDS YP_002809408.1 227080857 7771918 complement(679960..681108) 1 NC_012578.1 nptA protein 681108 ntpA 7771918 ntpA Vibrio cholerae M66-2 nptA protein YP_002809408.1 679960 R 579112 CDS YP_002809409.1 227080858 7771919 681503..682393 1 NC_012578.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 682393 nhaR 7771919 nhaR Vibrio cholerae M66-2 transcriptional activator NhaR YP_002809409.1 681503 D 579112 CDS YP_002809410.1 227080859 7771920 682592..682918 1 NC_012578.1 transcriptional activator HlyU 682918 hlyU 7771920 hlyU Vibrio cholerae M66-2 transcriptional activator HlyU YP_002809410.1 682592 D 579112 CDS YP_002809411.1 227080860 7771921 complement(682987..683247) 1 NC_012578.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 683247 rpsT 7771921 rpsT Vibrio cholerae M66-2 30S ribosomal protein S20 YP_002809411.1 682987 R 579112 CDS YP_002809412.1 227080861 7771922 683490..685067 1 NC_012578.1 MviN protein 685067 mviN 7771922 mviN Vibrio cholerae M66-2 MviN protein YP_002809412.1 683490 D 579112 CDS YP_002809413.1 227080862 7771923 685136..686104 1 NC_012578.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 686104 ribF 7771923 ribF Vibrio cholerae M66-2 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002809413.1 685136 D 579112 CDS YP_002809414.1 227080863 7771924 686135..688984 1 NC_012578.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 688984 ileS 7771924 ileS Vibrio cholerae M66-2 isoleucyl-tRNA synthetase YP_002809414.1 686135 D 579112 CDS YP_002809415.1 227080864 7771925 689000..689515 1 NC_012578.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 689515 lspA 7771925 lspA Vibrio cholerae M66-2 lipoprotein signal peptidase YP_002809415.1 689000 D 579112 CDS YP_002809416.1 227080865 7771926 689678..690112 1 NC_012578.1 FKBP-type peptidyl-prolyl cis-trans isomerase 690112 fkpB 7771926 fkpB Vibrio cholerae M66-2 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002809416.1 689678 D 579112 CDS YP_002809417.1 227080866 7771927 690147..691109 1 NC_012578.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 691109 ispH 7771927 ispH Vibrio cholerae M66-2 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002809417.1 690147 D 579112 CDS YP_002809418.1 227080867 7771928 691140..691235 1 NC_012578.1 hypothetical protein 691235 7771928 VCM66_0644 Vibrio cholerae M66-2 hypothetical protein YP_002809418.1 691140 D 579112 CDS YP_002809419.1 227080868 7771929 complement(691246..692730) 1 NC_012578.1 putative carbon starvation protein A 692730 7771929 VCM66_0645 Vibrio cholerae M66-2 putative carbon starvation protein A YP_002809419.1 691246 R 579112 CDS YP_002809420.1 227080869 7771930 692983..693324 1 NC_012578.1 putative lipoprotein 693324 7771930 VCM66_0646 Vibrio cholerae M66-2 putative lipoprotein YP_002809420.1 692983 D 579112 CDS YP_002809421.1 227080870 7771931 693340..695139 1 NC_012578.1 putative Cell volume regulation protein 695139 7771931 VCM66_0647 Vibrio cholerae M66-2 putative Cell volume regulation protein YP_002809421.1 693340 D 579112 CDS YP_002809422.1 227080871 7771932 complement(695163..696086) 1 NC_012578.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 696086 7771932 VCM66_0648 Vibrio cholerae M66-2 N-acetylmuramic acid-6-phosphate etherase YP_002809422.1 695163 R 579112 CDS YP_002809423.1 227080872 7771933 complement(696104..697216) 1 NC_012578.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 697216 anmK 7771933 anmK Vibrio cholerae M66-2 anhydro-N-acetylmuramic acid kinase YP_002809423.1 696104 R 579112 CDS YP_002809424.1 227080873 7771934 697322..698314 1 NC_012578.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 698314 exoII 7771934 exoII Vibrio cholerae M66-2 beta-hexosaminidase YP_002809424.1 697322 D 579112 CDS YP_002809425.1 227080874 7771935 complement(698341..699054) 1 NC_012578.1 unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 699054 7771935 VCM66_0651 Vibrio cholerae M66-2 putative two-component response-regulatory protein YehT YP_002809425.1 698341 R 579112 CDS YP_002809426.1 227080875 7771936 complement(699064..700740) 1 NC_012578.1 GAF/HisKin family protein 700740 7771936 VCM66_0652 Vibrio cholerae M66-2 GAF/HisKin family protein YP_002809426.1 699064 R 579112 CDS YP_002809427.1 227080876 7771937 700982..702055 1 NC_012578.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 702055 aroF 7771937 aroF Vibrio cholerae M66-2 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002809427.1 700982 D 579112 CDS YP_002809428.1 227080877 7771938 702068..703195 1 NC_012578.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 703195 tyrA 7771938 tyrA Vibrio cholerae M66-2 bifunctional chorismate mutase/prephenate dehydrogenase YP_002809428.1 702068 D 579112 CDS YP_002809429.1 227080878 7771939 complement(703262..703693) 1 NC_012578.1 hypothetical protein 703693 7771939 VCM66_0655 Vibrio cholerae M66-2 hypothetical protein YP_002809429.1 703262 R 579112 CDS YP_002809430.1 227080879 7771940 complement(703804..705471) 1 NC_012578.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 705471 7771940 VCM66_0656 Vibrio cholerae M66-2 putative ABC transporter ATP-binding protein YP_002809430.1 703804 R 579112 CDS YP_002809431.1 227080880 7771941 705656..705751 1 NC_012578.1 hypothetical protein 705751 7771941 VCM66_0657 Vibrio cholerae M66-2 hypothetical protein YP_002809431.1 705656 D 579112 CDS YP_002809432.1 227080881 7773954 707790..708146 1 NC_012578.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 708146 7773954 VCM66_0659 Vibrio cholerae M66-2 Trp operon repressor YP_002809432.1 707790 D 579112 CDS YP_002809433.1 227080882 7771943 complement(708224..708775) 1 NC_012578.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 708775 7771943 VCM66_0660 Vibrio cholerae M66-2 NTPase YP_002809433.1 708224 R 579112 CDS YP_002809434.1 227080883 7771944 complement(708696..711071) 1 NC_012578.1 c-di-GMP phosphodiesterase A-like protein 711071 mbaA 7771944 mbaA Vibrio cholerae M66-2 c-di-GMP phosphodiesterase A-like protein YP_002809434.1 708696 R 579112 CDS YP_002809435.1 227080884 7771945 complement(711055..712134) 1 NC_012578.1 putative spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein 712134 7771945 VCM66_0662 Vibrio cholerae M66-2 putative spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein YP_002809435.1 711055 R 579112 CDS YP_002809436.1 227080885 7771946 complement(712277..713452) 1 NC_012578.1 chorismate mutase/prephenate dehydratase 713452 pheA 7771946 pheA Vibrio cholerae M66-2 chorismate mutase/prephenate dehydratase YP_002809436.1 712277 R 579112 CDS YP_002809437.1 227080886 7771947 complement(713692..714018) 1 NC_012578.1 putative sigma-54 modulation protein 714018 7771947 VCM66_0664 Vibrio cholerae M66-2 putative sigma-54 modulation protein YP_002809437.1 713692 R 579112 CDS YP_002809438.1 227080887 7771948 714297..714425 1 NC_012578.1 hypothetical protein 714425 7771948 VCM66_0665 Vibrio cholerae M66-2 hypothetical protein YP_002809438.1 714297 D 579112 CDS YP_002809439.1 227080888 7771949 complement(714420..715181) 1 NC_012578.1 hypothetical protein 715181 7771949 VCM66_0666 Vibrio cholerae M66-2 hypothetical protein YP_002809439.1 714420 R 579112 CDS YP_002809440.1 227080889 7771950 715300..716274 1 NC_012578.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 716274 rluD 7771950 rluD Vibrio cholerae M66-2 23S rRNA pseudouridine synthase D YP_002809440.1 715300 D 579112 CDS YP_002809441.1 227080890 7771951 716277..716999 1 NC_012578.1 hypothetical protein 716999 7771951 VCM66_0668 Vibrio cholerae M66-2 hypothetical protein YP_002809441.1 716277 D 579112 CDS YP_002809442.1 227080891 7771952 717124..719697 1 NC_012578.1 clpB protein 719697 clpB-1 7771952 clpB-1 Vibrio cholerae M66-2 clpB protein YP_002809442.1 717124 D 579112 CDS YP_002809443.1 227080892 7771953 719946..720038 1 NC_012578.1 hypothetical protein 720038 7771953 VCM66_0670 Vibrio cholerae M66-2 hypothetical protein YP_002809443.1 719946 D 579112 CDS YP_002809444.1 227080893 7774010 725668..725991 1 NC_012578.1 hypothetical protein 725991 7774010 VCM66_0672 Vibrio cholerae M66-2 hypothetical protein YP_002809444.1 725668 D 579112 CDS YP_002809445.1 227080894 7771955 726001..726723 1 NC_012578.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 726723 frp 7771955 frp Vibrio cholerae M66-2 nitroreductase A YP_002809445.1 726001 D 579112 CDS YP_002809446.1 227080895 7771956 complement(726758..727012) 1 NC_012578.1 ferredoxin 727012 7771956 VCM66_0674 Vibrio cholerae M66-2 ferredoxin YP_002809446.1 726758 R 579112 CDS YP_002809447.1 227080896 7771957 complement(727015..728415) 1 NC_012578.1 putative protease 728415 7771957 VCM66_0675 Vibrio cholerae M66-2 putative protease YP_002809447.1 727015 R 579112 CDS YP_002809448.1 227080897 7771958 complement(728566..729480) 1 NC_012578.1 Required for efficient pilin antigenic variation; recombination associated protein 729480 rdgC 7771958 rdgC Vibrio cholerae M66-2 recombination associated protein YP_002809448.1 728566 R 579112 CDS YP_002809449.1 227080898 7771959 729717..730406 1 NC_012578.1 DNA-binding response regulator PhoB 730406 phoB 7771959 phoB Vibrio cholerae M66-2 DNA-binding response regulator PhoB YP_002809449.1 729717 D 579112 CDS YP_002809450.1 227080899 7771960 730428..731729 1 NC_012578.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 731729 phoR 7771960 phoR Vibrio cholerae M66-2 phosphate regulon sensor protein YP_002809450.1 730428 D 579112 CDS YP_002809451.1 227080900 7771961 731726..732703 1 NC_012578.1 putative phosphate ABC transporter periplasmic phosphate-binding protein 732703 7771961 VCM66_0679 Vibrio cholerae M66-2 putative phosphate ABC transporter periplasmic phosphate-binding protein YP_002809451.1 731726 D 579112 CDS YP_002809452.1 227080901 7771962 complement(732771..734342) 1 NC_012578.1 exopolyphosphatase 734342 ppx 7771962 ppx Vibrio cholerae M66-2 exopolyphosphatase YP_002809452.1 732771 R 579112 CDS YP_002809453.1 227080902 7771963 complement(734254..736359) 1 NC_012578.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 736359 ppk 7771963 ppk Vibrio cholerae M66-2 polyphosphate kinase YP_002809453.1 734254 R 579112 CDS YP_002809454.1 227080903 7771964 736558..738753 1 NC_012578.1 phosphate ABC transporter permease 738753 pstC-1 7771964 pstC-1 Vibrio cholerae M66-2 phosphate ABC transporter permease YP_002809454.1 736558 D 579112 CDS YP_002809455.1 227080904 7771965 738763..740409 1 NC_012578.1 phosphate ABC transporter permease 740409 pstA-1 7771965 pstA-1 Vibrio cholerae M66-2 phosphate ABC transporter permease YP_002809455.1 738763 D 579112 CDS YP_002809456.1 227080905 7771966 740412..741233 1 NC_012578.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 741233 pstB-1 7771966 pstB-1 Vibrio cholerae M66-2 phosphate transporter ATP-binding protein YP_002809456.1 740412 D 579112 CDS YP_002809457.1 227080906 7771967 741267..741977 1 NC_012578.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 741977 phoU 7771967 phoU Vibrio cholerae M66-2 transcriptional regulator PhoU YP_002809457.1 741267 D 579112 CDS YP_002809458.1 227080907 7771968 complement(742038..742814) 1 NC_012578.1 hypothetical protein 742814 7771968 VCM66_0686 Vibrio cholerae M66-2 hypothetical protein YP_002809458.1 742038 R 579112 CDS YP_002809459.1 227080908 7771969 742867..742968 1 NC_012578.1 hypothetical protein 742968 7771969 VCM66_0687 Vibrio cholerae M66-2 hypothetical protein YP_002809459.1 742867 D 579112 CDS YP_002809460.1 227080909 7771970 complement(743017..743781) 1 NC_012578.1 copper homeostasis protein 743781 cutC 7771970 cutC Vibrio cholerae M66-2 copper homeostasis protein YP_002809460.1 743017 R 579112 CDS YP_002809461.1 227080910 7771971 complement(744116..744739) 1 NC_012578.1 antioxidant, AhpC/Tsa family 744739 7771971 VCM66_0689 Vibrio cholerae M66-2 antioxidant, AhpC/Tsa family YP_002809461.1 744116 R 579112 CDS YP_002809462.1 227080911 7771972 744943..745848 1 NC_012578.1 LysR family transcriptional regulator 745848 7771972 VCM66_0690 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002809462.1 744943 D 579112 CDS YP_002809463.1 227080912 7771973 complement(746083..746202) 1 NC_012578.1 hypothetical protein 746202 7771973 VCM66_0691 Vibrio cholerae M66-2 hypothetical protein YP_002809463.1 746083 R 579112 CDS YP_002809464.1 227080913 7771974 746399..748069 1 NC_012578.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 748069 aceB 7771974 aceB Vibrio cholerae M66-2 malate synthase YP_002809464.1 746399 D 579112 CDS YP_002809465.1 227080914 7771975 complement(748074..748175) 1 NC_012578.1 hypothetical protein 748175 7771975 VCM66_0693 Vibrio cholerae M66-2 hypothetical protein YP_002809465.1 748074 R 579112 CDS YP_002809466.1 227080915 7771976 748199..749512 1 NC_012578.1 isocitrate lyase 749512 aceA 7771976 aceA Vibrio cholerae M66-2 isocitrate lyase YP_002809466.1 748199 D 579112 CDS YP_002809467.1 227080916 7771977 complement(749665..750174) 1 NC_012578.1 acetoin utilization protein 750174 7771977 VCM66_0695 Vibrio cholerae M66-2 acetoin utilization protein YP_002809467.1 749665 R 579112 CDS YP_002809468.1 227080917 7771978 750238..750342 1 NC_012578.1 hypothetical protein 750342 7771978 VCM66_0696 Vibrio cholerae M66-2 hypothetical protein YP_002809468.1 750238 D 579112 CDS YP_002809469.1 227080918 7771979 750404..751462 1 NC_012578.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 751462 queA 7771979 queA Vibrio cholerae M66-2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002809469.1 750404 D 579112 CDS YP_002809470.1 227080919 7771980 complement(751417..751680) 1 NC_012578.1 hypothetical protein 751680 7771980 VCM66_0698 Vibrio cholerae M66-2 hypothetical protein YP_002809470.1 751417 R 579112 CDS YP_002809471.1 227080920 7771981 751691..752830 1 NC_012578.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 752830 tgt 7771981 tgt Vibrio cholerae M66-2 queuine tRNA-ribosyltransferase YP_002809471.1 751691 D 579112 CDS YP_002809472.1 227080921 7771982 752935..753267 1 NC_012578.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 753267 yajC 7771982 yajC Vibrio cholerae M66-2 preprotein translocase subunit YajC YP_002809472.1 752935 D 579112 CDS YP_002809473.1 227080922 7771983 753289..755142 1 NC_012578.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 755142 secD 7771983 secD Vibrio cholerae M66-2 preprotein translocase subunit SecD YP_002809473.1 753289 D 579112 CDS YP_002809474.1 227080923 7771984 755157..756104 1 NC_012578.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 756104 secF 7771984 secF Vibrio cholerae M66-2 preprotein translocase subunit SecF YP_002809474.1 755157 D 579112 CDS YP_002809475.1 227080924 7771985 complement(756272..757138) 1 NC_012578.1 inositol monophosphate family protein 757138 7771985 VCM66_0703 Vibrio cholerae M66-2 inositol monophosphate family protein YP_002809475.1 756272 R 579112 CDS YP_002809476.1 227080925 7771986 757254..757988 1 NC_012578.1 RNA methyltransferase, TrmH family 757988 7771986 VCM66_0704 Vibrio cholerae M66-2 RNA methyltransferase, TrmH family YP_002809476.1 757254 D 579112 CDS YP_002809477.1 227080926 7771987 758058..758624 1 NC_012578.1 hypothetical protein 758624 7771987 VCM66_0705 Vibrio cholerae M66-2 hypothetical protein YP_002809477.1 758058 D 579112 CDS YP_002809478.1 227080927 7771988 758651..759865 1 NC_012578.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 759865 7771988 VCM66_0706 Vibrio cholerae M66-2 cysteine desulfurase YP_002809478.1 758651 D 579112 CDS YP_002809479.1 227080928 7771989 759902..760285 1 NC_012578.1 scaffold protein 760285 7771989 VCM66_0707 Vibrio cholerae M66-2 scaffold protein YP_002809479.1 759902 D 579112 CDS YP_002809480.1 227080929 7771990 760346..760669 1 NC_012578.1 hesB family protein 760669 7771990 VCM66_0708 Vibrio cholerae M66-2 hesB family protein YP_002809480.1 760346 D 579112 CDS YP_002809481.1 227080930 7771991 760718..761233 1 NC_012578.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 761233 hscB 7771991 hscB Vibrio cholerae M66-2 co-chaperone HscB YP_002809481.1 760718 D 579112 CDS YP_002809482.1 227080931 7771992 761257..763107 1 NC_012578.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 763107 hscA 7771992 hscA Vibrio cholerae M66-2 chaperone protein HscA YP_002809482.1 761257 D 579112 CDS YP_002809483.1 227080932 7771993 763040..763459 1 NC_012578.1 ferredoxin 763459 7771993 VCM66_0711 Vibrio cholerae M66-2 ferredoxin YP_002809483.1 763040 D 579112 CDS YP_002809484.1 227080933 7771994 763508..763702 1 NC_012578.1 hypothetical protein 763702 7771994 VCM66_0712 Vibrio cholerae M66-2 hypothetical protein YP_002809484.1 763508 D 579112 CDS YP_002809485.1 227080934 7771995 763877..765211 1 NC_012578.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 765211 pepB 7771995 pepB Vibrio cholerae M66-2 aminopeptidase B YP_002809485.1 763877 D 579112 CDS YP_002809486.1 227080935 7771996 765415..765843 1 NC_012578.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 765843 ndk 7771996 ndk Vibrio cholerae M66-2 nucleoside diphosphate kinase YP_002809486.1 765415 D 579112 CDS YP_002809487.1 227080936 7771997 766017..767138 1 NC_012578.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 767138 7771997 VCM66_0715 Vibrio cholerae M66-2 ribosomal RNA large subunit methyltransferase N YP_002809487.1 766017 D 579112 CDS YP_002809488.1 227080937 7771998 767353..768534 1 NC_012578.1 Putative HTH-type transcriptional regulator yfgA 768534 7771998 VCM66_0716 Vibrio cholerae M66-2 Putative HTH-type transcriptional regulator yfgA YP_002809488.1 767353 D 579112 CDS YP_002809489.1 227080938 7771999 768539..769669 1 NC_012578.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 769669 ispG 7771999 ispG Vibrio cholerae M66-2 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002809489.1 768539 D 579112 CDS YP_002809490.1 227080939 7772000 769695..770963 1 NC_012578.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 770963 hisS 7772000 hisS Vibrio cholerae M66-2 histidyl-tRNA synthetase YP_002809490.1 769695 D 579112 CDS YP_002809491.1 227080940 7772001 771000..771614 1 NC_012578.1 hypothetical protein 771614 7772001 VCM66_0719 Vibrio cholerae M66-2 hypothetical protein YP_002809491.1 771000 D 579112 CDS YP_002809492.1 227080941 7772002 771627..772787 1 NC_012578.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 772787 7772002 VCM66_0720 Vibrio cholerae M66-2 outer membrane protein assembly complex subunit YfgL YP_002809492.1 771627 D 579112 CDS YP_002809493.1 227080942 7772003 772980..774464 1 NC_012578.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 774464 engA 7772003 engA Vibrio cholerae M66-2 GTP-binding protein EngA YP_002809493.1 772980 D 579112 CDS YP_002809494.1 227080943 7772004 774485..775402 1 NC_012578.1 hypothetical protein 775402 7772004 VCM66_0722 Vibrio cholerae M66-2 hypothetical protein YP_002809494.1 774485 D 579112 CDS YP_002809495.1 227080944 7772005 775707..775940 1 NC_012578.1 hypothetical protein 775940 7772005 VCM66_0723 Vibrio cholerae M66-2 hypothetical protein YP_002809495.1 775707 D 579112 CDS YP_002809496.1 227080945 7772006 complement(775921..777261) 1 NC_012578.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 777261 xseA 7772006 xseA Vibrio cholerae M66-2 exodeoxyribonuclease VII large subunit YP_002809496.1 775921 R 579112 CDS YP_002809497.1 227080946 7772007 777463..778932 1 NC_012578.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 778932 guaB 7772007 guaB Vibrio cholerae M66-2 inosine 5'-monophosphate dehydrogenase YP_002809497.1 777463 D 579112 CDS YP_002809498.1 227080947 7772008 779039..780592 1 NC_012578.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 780592 guaA 7772008 guaA Vibrio cholerae M66-2 GMP synthase YP_002809498.1 779039 D 579112 CDS YP_002809499.1 227080948 7772009 780828..782552 1 NC_012578.1 putative chitinase 782552 7772009 VCM66_0727 Vibrio cholerae M66-2 putative chitinase YP_002809499.1 780828 D 579112 CDS YP_002809500.1 227080949 7772010 782743..783336 1 NC_012578.1 putative Inner membrane protein 783336 7772010 VCM66_0728 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809500.1 782743 D 579112 CDS YP_002809501.1 227080950 7772011 783648..784529 1 NC_012578.1 vibriobactin-specific isochorismatase 784529 vibB 7772011 vibB Vibrio cholerae M66-2 vibriobactin-specific isochorismatase YP_002809501.1 783648 D 579112 CDS YP_002809502.1 227080951 7772012 complement(784630..786261) 1 NC_012578.1 vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase 786261 vibE 7772012 vibE Vibrio cholerae M66-2 vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase YP_002809502.1 784630 R 579112 CDS YP_002809503.1 227080952 7772013 complement(786272..787459) 1 NC_012578.1 vibriobactin-specific isochorismate synthase 787459 vibC 7772013 vibC Vibrio cholerae M66-2 vibriobactin-specific isochorismate synthase YP_002809503.1 786272 R 579112 CDS YP_002809504.1 227080953 7772014 787627..788415 1 NC_012578.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 788415 vibA 7772014 vibA Vibrio cholerae M66-2 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002809504.1 787627 D 579112 CDS YP_002809505.1 227080954 7772015 complement(788427..789743) 1 NC_012578.1 vibriobactin synthetase, amide synthase subunit VibH 789743 vibH 7772015 vibH Vibrio cholerae M66-2 vibriobactin synthetase, amide synthase subunit VibH YP_002809505.1 788427 R 579112 CDS YP_002809506.1 227080955 7772016 789921..790898 1 NC_012578.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 790898 viuP 7772016 viuP Vibrio cholerae M66-2 iron-enterobactin transporter periplasmic binding protein YP_002809506.1 789921 D 579112 CDS YP_002809507.1 227080956 7772017 790895..791947 1 NC_012578.1 vibriobactin and enterobactin ABC transporter permease 791947 viuD 7772017 viuD Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter permease YP_002809507.1 790895 D 579112 CDS YP_002809508.1 227080957 7772018 791926..793002 1 NC_012578.1 vibriobactin and enterobactin ABC transporter permease 793002 viuG 7772018 viuG Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter permease YP_002809508.1 791926 D 579112 CDS YP_002809509.1 227080958 7772019 793119..793958 1 NC_012578.1 vibriobactin and enterobactin ABC transporter ATP-binding protein 793958 viuC 7772019 viuC Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter ATP-binding protein YP_002809509.1 793119 D 579112 CDS YP_002809510.1 227080959 7772020 793889..794674 1 NC_012578.1 vibriobactin synthase component D 794674 vibD 7772020 vibD Vibrio cholerae M66-2 vibriobactin synthase component D YP_002809510.1 793889 D 579112 CDS YP_002809511.1 227080960 7772021 794684..795610 1 NC_012578.1 LysR family transcriptional regulator 795610 7772021 VCM66_0739 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002809511.1 794684 D 579112 CDS YP_002809512.1 227080961 7772022 complement(795603..795713) 1 NC_012578.1 hypothetical protein 795713 7772022 VCM66_0740 Vibrio cholerae M66-2 hypothetical protein YP_002809512.1 795603 R 579112 CDS YP_002809513.1 227080962 7772023 795828..797810 1 NC_012578.1 hypothetical protein 797810 7772023 VCM66_0741 Vibrio cholerae M66-2 hypothetical protein YP_002809513.1 795828 D 579112 CDS YP_002809514.1 227080963 7772024 complement(797890..799440) 1 NC_012578.1 sodium/alanine symporter 799440 7772024 VCM66_0742 Vibrio cholerae M66-2 sodium/alanine symporter YP_002809514.1 797890 R 579112 CDS YP_002809515.1 227080964 7772025 complement(799719..799817) 1 NC_012578.1 hypothetical protein 799817 7772025 VCM66_0743 Vibrio cholerae M66-2 hypothetical protein YP_002809515.1 799719 R 579112 CDS YP_002809516.1 227080965 7772026 complement(799818..801083) 1 NC_012578.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 801083 dadA 7772026 dadA Vibrio cholerae M66-2 D-amino acid dehydrogenase small subunit YP_002809516.1 799818 R 579112 CDS YP_002809517.1 227080966 7772027 801184..802116 1 NC_012578.1 LysR family transcriptional regulator 802116 7772027 VCM66_0745 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002809517.1 801184 D 579112 CDS YP_002809518.1 227080967 7772028 802241..802570 1 NC_012578.1 DOPA-dioxygenase-like protein 802570 7772028 VCM66_0746 Vibrio cholerae M66-2 DOPA-dioxygenase-like protein YP_002809518.1 802241 D 579112 CDS YP_002809519.1 227080968 7772029 802736..803008 1 NC_012578.1 hypothetical protein 803008 7772029 VCM66_0747 Vibrio cholerae M66-2 hypothetical protein YP_002809519.1 802736 D 579112 CDS YP_002809520.1 227080969 7772030 complement(803042..803725) 1 NC_012578.1 transcriptional regulator CitB 803725 citB 7772030 citB Vibrio cholerae M66-2 transcriptional regulator CitB YP_002809520.1 803042 R 579112 CDS YP_002809521.1 227080970 7772031 complement(803739..805436) 1 NC_012578.1 sensor kinase citA 805436 citA 7772031 citA Vibrio cholerae M66-2 sensor kinase citA YP_002809521.1 803739 R 579112 CDS YP_002809522.1 227080971 7772032 complement(805507..806808) 1 NC_012578.1 oxaloacetate decarboxylase subunit beta 806808 oadB-2 7772032 oadB-2 Vibrio cholerae M66-2 oxaloacetate decarboxylase subunit beta YP_002809522.1 805507 R 579112 CDS YP_002809523.1 227080972 7772033 complement(806824..808623) 1 NC_012578.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 808623 oadA-2 7772033 oadA-2 Vibrio cholerae M66-2 oxaloacetate decarboxylase YP_002809523.1 806824 R 579112 CDS YP_002809524.1 227080973 7772034 complement(808642..809061) 1 NC_012578.1 putative oxaloacetate decarboxylase gamma chain 2 809061 7772034 VCM66_0752 Vibrio cholerae M66-2 putative oxaloacetate decarboxylase gamma chain 2 YP_002809524.1 808642 R 579112 CDS YP_002809525.1 227080974 7772035 complement(809009..810355) 1 NC_012578.1 citrate/sodium symporter 810355 citS 7772035 citS Vibrio cholerae M66-2 citrate/sodium symporter YP_002809525.1 809009 R 579112 CDS YP_002809526.1 227080975 7772036 810617..811687 1 NC_012578.1 citrate (pro-3S)-lyase ligase 811687 citC 7772036 citC Vibrio cholerae M66-2 citrate (pro-3S)-lyase ligase YP_002809526.1 810617 D 579112 CDS YP_002809527.1 227080976 7772037 811739..812035 1 NC_012578.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 812035 citD 7772037 citD Vibrio cholerae M66-2 citrate lyase subunit gamma YP_002809527.1 811739 D 579112 CDS YP_002809528.1 227080977 7772038 812017..812907 1 NC_012578.1 citrate lyase subunit beta 812907 citE 7772038 citE Vibrio cholerae M66-2 citrate lyase subunit beta YP_002809528.1 812017 D 579112 CDS YP_002809529.1 227080978 7772039 812843..814447 1 NC_012578.1 citrate lyase subunit alpha 814447 citF 7772039 citF Vibrio cholerae M66-2 citrate lyase subunit alpha YP_002809529.1 812843 D 579112 CDS YP_002809530.1 227080979 7772040 814444..814980 1 NC_012578.1 citX protein 814980 citX 7772040 citX Vibrio cholerae M66-2 citX protein YP_002809530.1 814444 D 579112 CDS YP_002809531.1 227080980 7772041 814958..815899 1 NC_012578.1 citG protein 815899 citG 7772041 citG Vibrio cholerae M66-2 citG protein YP_002809531.1 814958 D 579112 CDS YP_002809532.1 227080981 7772042 816246..816644 1 NC_012578.1 hypothetical protein 816644 7772042 VCM66_0760 Vibrio cholerae M66-2 hypothetical protein YP_002809532.1 816246 D 579112 CDS YP_002809533.1 227080982 7772043 816719..817492 1 NC_012578.1 RNA methyltransferase, TrmH family 817492 7772043 VCM66_0761 Vibrio cholerae M66-2 RNA methyltransferase, TrmH family YP_002809533.1 816719 D 579112 CDS YP_002809534.1 227080983 7772044 complement(817671..817994) 1 NC_012578.1 ferredoxin 817994 7772044 VCM66_0762 Vibrio cholerae M66-2 ferredoxin YP_002809534.1 817671 R 579112 CDS YP_002809535.1 227080984 7772045 818036..818131 1 NC_012578.1 hypothetical protein 818131 7772045 VCM66_0763 Vibrio cholerae M66-2 hypothetical protein YP_002809535.1 818036 D 579112 CDS YP_002809536.1 227080985 7772046 818241..819857 1 NC_012578.1 hypothetical protein 819857 7772046 VCM66_0764 Vibrio cholerae M66-2 hypothetical protein YP_002809536.1 818241 D 579112 CDS YP_002809537.1 227080986 7772047 complement(819925..820608) 1 NC_012578.1 hypothetical protein 820608 7772047 VCM66_0765 Vibrio cholerae M66-2 hypothetical protein YP_002809537.1 819925 R 579112 CDS YP_002809538.1 227080987 7772048 complement(820580..820732) 1 NC_012578.1 hypothetical protein 820732 7772048 VCM66_0766 Vibrio cholerae M66-2 hypothetical protein YP_002809538.1 820580 R 579112 CDS YP_002809539.1 227080988 7772049 820741..822510 1 NC_012578.1 hypothetical protein 822510 7772049 VCM66_0767 Vibrio cholerae M66-2 hypothetical protein YP_002809539.1 820741 D 579112 CDS YP_002809540.1 227080989 7772050 822702..823217 1 NC_012578.1 hypothetical protein 823217 7772050 VCM66_0768 Vibrio cholerae M66-2 hypothetical protein YP_002809540.1 822702 D 579112 CDS YP_002809541.1 227080990 7772051 complement(823551..824255) 1 NC_012578.1 hypothetical protein 824255 7772051 VCM66_0769 Vibrio cholerae M66-2 hypothetical protein YP_002809541.1 823551 R 579112 CDS YP_002809542.1 227080991 7772052 complement(824325..827264) 1 NC_012578.1 helicase-like protein 827264 7772052 VCM66_0770 Vibrio cholerae M66-2 helicase-like protein YP_002809542.1 824325 R 579112 CDS YP_002809543.1 227080992 7772053 complement(827265..827843) 1 NC_012578.1 tellurite resistance protein-like protein 827843 7772053 VCM66_0771 Vibrio cholerae M66-2 tellurite resistance protein-like protein YP_002809543.1 827265 R 579112 CDS YP_002809544.1 227080993 7772054 complement(828271..828750) 1 NC_012578.1 putative transcriptional regulator 828750 7772054 VCM66_0772 Vibrio cholerae M66-2 putative transcriptional regulator YP_002809544.1 828271 R 579112 CDS YP_002809545.1 227080994 7772055 complement(828735..830105) 1 NC_012578.1 hypothetical protein 830105 7772055 VCM66_0773 Vibrio cholerae M66-2 hypothetical protein YP_002809545.1 828735 R 579112 CDS YP_002809546.1 227080995 7772056 complement(830216..830398) 1 NC_012578.1 hypothetical protein 830398 7772056 VCM66_0774 Vibrio cholerae M66-2 hypothetical protein YP_002809546.1 830216 R 579112 CDS YP_002809547.1 227080996 7772057 830694..831677 1 NC_012578.1 ISVch1 transposase, IS481 group 831677 7772057 VCM66_0775 Vibrio cholerae M66-2 ISVch1 transposase, IS481 group YP_002809547.1 830694 D 579112 CDS YP_002809548.1 227080997 7773955 complement(832725..834350) 1 NC_012578.1 aldehyde dehydrogenase 834350 aldA-1 7773955 aldA-1 Vibrio cholerae M66-2 aldehyde dehydrogenase YP_002809548.1 832725 R 579112 CDS YP_002809549.1 227080998 7772059 834426..837467 1 NC_012578.1 ToxR-activated gene A protein 837467 tagA 7772059 tagA Vibrio cholerae M66-2 ToxR-activated gene A protein YP_002809549.1 834426 D 579112 CDS YP_002809550.1 227080999 7772060 837580..842181 1 NC_012578.1 hypothetical protein 842181 7772060 VCM66_0779 Vibrio cholerae M66-2 hypothetical protein YP_002809550.1 837580 D 579112 CDS YP_002809551.1 227081000 7772061 842178..843116 1 NC_012578.1 hypothetical protein 843116 7772061 VCM66_0780 Vibrio cholerae M66-2 hypothetical protein YP_002809551.1 842178 D 579112 CDS YP_002809552.1 227081001 7772062 843226..843720 1 NC_012578.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 843720 tpx 7772062 tpx Vibrio cholerae M66-2 thiol peroxidase YP_002809552.1 843226 D 579112 CDS YP_002809553.1 227081002 7772063 complement(843996..845858) 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein I 845858 tcpI 7772063 tcpI Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein I YP_002809553.1 843996 R 579112 CDS YP_002809554.1 227081003 7772064 846298..846963 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein P 846963 tcpP 7772064 tcpP Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein P YP_002809554.1 846298 D 579112 CDS YP_002809555.1 227081004 7772065 846948..847358 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein H 847358 tcpH 7772065 tcpH Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein H YP_002809555.1 846948 D 579112 CDS YP_002809556.1 227081005 7772066 847901..848575 1 NC_012578.1 toxin co-regulated pilin 848575 tcpA 7772066 tcpA Vibrio cholerae M66-2 toxin co-regulated pilin YP_002809556.1 847901 D 579112 CDS YP_002809557.1 227081006 7772067 848655..849947 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein B 849947 tcpB 7772067 tcpB Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein B YP_002809557.1 848655 D 579112 CDS YP_002809558.1 227081007 7772068 849947..850399 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein Q 850399 tcpQ 7772068 tcpQ Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein Q YP_002809558.1 849947 D 579112 CDS YP_002809559.1 227081008 7772069 850402..851871 1 NC_012578.1 toxin co-regulated pilus biosynthesis outer membrane protein C 851871 tcpC 7772069 tcpC Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis outer membrane protein C YP_002809559.1 850402 D 579112 CDS YP_002809560.1 227081009 7772070 851864..852319 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein R 852319 tcpR 7772070 tcpR Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein R YP_002809560.1 851864 D 579112 CDS YP_002809561.1 227081010 7772071 852307..853143 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein D 853143 tcpD 7772071 tcpD Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein D YP_002809561.1 852307 D 579112 CDS YP_002809562.1 227081011 7772072 853159..853617 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein S 853617 tcpS 7772072 tcpS Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein S YP_002809562.1 853159 D 579112 CDS YP_002809563.1 227081012 7772073 853607..855118 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein T 855118 tcpT 7772073 tcpT Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein T YP_002809563.1 853607 D 579112 CDS YP_002809564.1 227081013 7772074 855093..856115 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein E 856115 tcpE 7772074 tcpE Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein E YP_002809564.1 855093 D 579112 CDS YP_002809565.1 227081014 7772075 856125..857141 1 NC_012578.1 toxin co-regulated pilus biosynthesis protein F 857141 tcpF 7772075 tcpF Vibrio cholerae M66-2 toxin co-regulated pilus biosynthesis protein F YP_002809565.1 856125 D 579112 CDS YP_002809566.1 227081015 7772076 857348..858178 1 NC_012578.1 TCP pilus virulence regulatory protein 858178 7772076 VCM66_0795 Vibrio cholerae M66-2 TCP pilus virulence regulatory protein YP_002809566.1 857348 D 579112 CDS YP_002809567.1 227081016 7772077 858178..858939 1 NC_012578.1 leader peptidase TcpJ 858939 tcpJ 7772077 tcpJ Vibrio cholerae M66-2 leader peptidase TcpJ YP_002809567.1 858178 D 579112 CDS YP_002809568.1 227081017 7772078 858946..860826 1 NC_012578.1 accessory colonization factor AcfB 860826 acfB 7772078 acfB Vibrio cholerae M66-2 accessory colonization factor AcfB YP_002809568.1 858946 D 579112 CDS YP_002809569.1 227081018 7772079 860832..861602 1 NC_012578.1 accessory colonization factor AcfC 861602 acfC 7772079 acfC Vibrio cholerae M66-2 accessory colonization factor AcfC YP_002809569.1 860832 D 579112 CDS YP_002809570.1 227081019 7772080 861618..862091 1 NC_012578.1 hypothetical protein 862091 7772080 VCM66_0799 Vibrio cholerae M66-2 hypothetical protein YP_002809570.1 861618 D 579112 CDS YP_002809571.1 227081020 7772081 862100..863008 1 NC_012578.1 tagE protein 863008 tagE-1 7772081 tagE-1 Vibrio cholerae M66-2 tagE protein YP_002809571.1 862100 D 579112 CDS YP_002809572.1 227081021 7772082 complement(863011..863658) 1 NC_012578.1 accessory colonization factor AcfA 863658 acfA 7772082 acfA Vibrio cholerae M66-2 accessory colonization factor AcfA YP_002809572.1 863011 R 579112 CDS YP_002809573.1 227081022 7772083 863831..868393 1 NC_012578.1 putative lipoprotein 868393 7772083 VCM66_0802 Vibrio cholerae M66-2 putative lipoprotein YP_002809573.1 863831 D 579112 CDS YP_002809574.1 227081023 7773956 complement(870308..871576) 1 NC_012578.1 integrase, phage family 871576 7773956 VCM66_0804 Vibrio cholerae M66-2 integrase, phage family YP_002809574.1 870308 R 579112 CDS YP_002809575.1 227081024 7772085 complement(872178..872663) 1 NC_012578.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 872663 smpB 7772085 smpB Vibrio cholerae M66-2 SsrA-binding protein YP_002809575.1 872178 R 579112 CDS YP_002809576.1 227081025 7772086 872841..873281 1 NC_012578.1 hypothetical protein 873281 7772086 VCM66_0806 Vibrio cholerae M66-2 hypothetical protein YP_002809576.1 872841 D 579112 CDS YP_002809577.1 227081026 7772087 873278..873589 1 NC_012578.1 hypothetical protein 873589 7772087 VCM66_0807 Vibrio cholerae M66-2 hypothetical protein YP_002809577.1 873278 D 579112 CDS YP_002809578.1 227081027 7772088 complement(873667..874077) 1 NC_012578.1 small protein A 874077 smpA 7772088 smpA Vibrio cholerae M66-2 small protein A YP_002809578.1 873667 R 579112 CDS YP_002809579.1 227081028 7772089 complement(874185..875849) 1 NC_012578.1 recombination and repair protein 875849 recN 7772089 recN Vibrio cholerae M66-2 recombination and repair protein YP_002809579.1 874185 R 579112 CDS YP_002809580.1 227081029 7772090 complement(875979..876863) 1 NC_012578.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 876863 ppnK 7772090 ppnK Vibrio cholerae M66-2 inorganic polyphosphate/ATP-NAD kinase YP_002809580.1 875979 R 579112 CDS YP_002809581.1 227081030 7772091 877009..877611 1 NC_012578.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 877611 grpE 7772091 grpE Vibrio cholerae M66-2 heat shock protein GrpE YP_002809581.1 877009 D 579112 CDS YP_002809582.1 227081031 7772092 877875..879782 1 NC_012578.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 879782 dnaK 7772092 dnaK Vibrio cholerae M66-2 molecular chaperone DnaK YP_002809582.1 877875 D 579112 CDS YP_002809583.1 227081032 7772093 879983..881128 1 NC_012578.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 881128 dnaJ 7772093 dnaJ Vibrio cholerae M66-2 chaperone protein DnaJ YP_002809583.1 879983 D 579112 CDS YP_002809584.1 227081033 7772094 complement(881178..881621) 1 NC_012578.1 putative fimbrial assembly protein PilE 881621 7772094 VCM66_0814 Vibrio cholerae M66-2 putative fimbrial assembly protein PilE YP_002809584.1 881178 R 579112 CDS YP_002809585.1 227081034 7772095 881676..882230 1 NC_012578.1 putative type IV pilin 882230 7772095 VCM66_0815 Vibrio cholerae M66-2 putative type IV pilin YP_002809585.1 881676 D 579112 CDS YP_002809586.1 227081035 7772096 882199..882801 1 NC_012578.1 hypothetical protein 882801 7772096 VCM66_0816 Vibrio cholerae M66-2 hypothetical protein YP_002809586.1 882199 D 579112 CDS YP_002809587.1 227081036 7772097 882792..884033 1 NC_012578.1 hypothetical protein 884033 7772097 VCM66_0817 Vibrio cholerae M66-2 hypothetical protein YP_002809587.1 882792 D 579112 CDS YP_002809588.1 227081037 7772098 884023..884436 1 NC_012578.1 putative type IV pilin 884436 7772098 VCM66_0818 Vibrio cholerae M66-2 putative type IV pilin YP_002809588.1 884023 D 579112 CDS YP_002809589.1 227081038 7772099 884473..884841 1 NC_012578.1 hypothetical protein 884841 7772099 VCM66_0819 Vibrio cholerae M66-2 hypothetical protein YP_002809589.1 884473 D 579112 CDS YP_002809590.1 227081039 7772100 884834..886393 1 NC_012578.1 Aminobenzoyl-glutamate transport protein 886393 7772100 VCM66_0820 Vibrio cholerae M66-2 Aminobenzoyl-glutamate transport protein YP_002809590.1 884834 D 579112 CDS YP_002809591.1 227081040 7772101 886462..887043 1 NC_012578.1 yfhC protein 887043 yfhC 7772101 yfhC Vibrio cholerae M66-2 yfhC protein YP_002809591.1 886462 D 579112 CDS YP_002809592.1 227081041 7772102 complement(887089..887220) 1 NC_012578.1 hypothetical protein 887220 7772102 VCM66_0822 Vibrio cholerae M66-2 hypothetical protein YP_002809592.1 887089 R 579112 CDS YP_002809593.1 227081042 7772103 complement(887399..888991) 1 NC_012578.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 888991 7772103 VCM66_0823 Vibrio cholerae M66-2 putative transglycosylase YP_002809593.1 887399 R 579112 CDS YP_002809594.1 227081043 7772104 complement(888991..889113) 1 NC_012578.1 hypothetical protein 889113 7772104 VCM66_0824 Vibrio cholerae M66-2 hypothetical protein YP_002809594.1 888991 R 579112 CDS YP_002809595.1 227081044 7772105 889092..889304 1 NC_012578.1 hypothetical protein 889304 7772105 VCM66_0825 Vibrio cholerae M66-2 hypothetical protein YP_002809595.1 889092 D 579112 CDS YP_002809596.1 227081045 7772106 889301..893194 1 NC_012578.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 893194 purL 7772106 purL Vibrio cholerae M66-2 phosphoribosylformylglycinamidine synthase YP_002809596.1 889301 D 579112 CDS YP_002809597.1 227081046 7772107 893369..893806 1 NC_012578.1 IS1004 transposase 893806 tnpA 7772107 tnpA Vibrio cholerae M66-2 IS1004 transposase YP_002809597.1 893369 D 579112 CDS YP_002809598.1 227081047 7772108 complement(893917..894108) 1 NC_012578.1 hypothetical protein 894108 7772108 VCM66_0828 Vibrio cholerae M66-2 hypothetical protein YP_002809598.1 893917 R 579112 CDS YP_002809599.1 227081048 7772109 complement(894114..894317) 1 NC_012578.1 hypothetical protein 894317 7772109 VCM66_0829 Vibrio cholerae M66-2 hypothetical protein YP_002809599.1 894114 R 579112 CDS YP_002809600.1 227081049 7772110 complement(894420..895064) 1 NC_012578.1 putative Inner membrane protein 895064 7772110 VCM66_0830 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809600.1 894420 R 579112 CDS YP_002809601.1 227081050 7772111 895097..895288 1 NC_012578.1 hypothetical protein 895288 7772111 VCM66_0831 Vibrio cholerae M66-2 hypothetical protein YP_002809601.1 895097 D 579112 CDS YP_002809602.1 227081051 7772112 complement(895306..897021) 1 NC_012578.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 897021 proS 7772112 proS Vibrio cholerae M66-2 prolyl-tRNA synthetase YP_002809602.1 895306 R 579112 CDS YP_002809603.1 227081052 7772113 complement(897247..897942) 1 NC_012578.1 hypothetical protein 897942 7772113 VCM66_0833 Vibrio cholerae M66-2 hypothetical protein YP_002809603.1 897247 R 579112 CDS YP_002809604.1 227081053 7772114 complement(897958..898056) 1 NC_012578.1 hypothetical protein 898056 7772114 VCM66_0834 Vibrio cholerae M66-2 hypothetical protein YP_002809604.1 897958 R 579112 CDS YP_002809605.1 227081054 7772115 898077..898334 1 NC_012578.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 898334 rpmE2 7772115 rpmE2 Vibrio cholerae M66-2 50S ribosomal protein L31 type B YP_002809605.1 898077 D 579112 CDS YP_002809606.1 227081055 7772116 898331..898456 1 NC_012578.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 898456 rpmJ 7772116 rpmJ Vibrio cholerae M66-2 50S ribosomal protein L36 YP_002809606.1 898331 D 579112 CDS YP_002809607.1 227081056 7772117 898639..900243 1 NC_012578.1 Aminobenzoyl-glutamate transport protein 900243 7772117 VCM66_0837 Vibrio cholerae M66-2 Aminobenzoyl-glutamate transport protein YP_002809607.1 898639 D 579112 CDS YP_002809608.1 227081057 7772118 complement(900309..900758) 1 NC_012578.1 hypothetical protein 900758 7772118 VCM66_0838 Vibrio cholerae M66-2 hypothetical protein YP_002809608.1 900309 R 579112 CDS YP_002809609.1 227081058 7772119 complement(900755..901054) 1 NC_012578.1 hypothetical protein 901054 7772119 VCM66_0839 Vibrio cholerae M66-2 hypothetical protein YP_002809609.1 900755 R 579112 CDS YP_002809610.1 227081059 7772120 complement(901667..901780) 1 NC_012578.1 hypothetical protein 901780 7772120 VCM66_0840 Vibrio cholerae M66-2 hypothetical protein YP_002809610.1 901667 R 579112 CDS YP_002809611.1 227081060 7772121 901819..902442 1 NC_012578.1 acetyltransferase-like protein 902442 7772121 VCM66_0841 Vibrio cholerae M66-2 acetyltransferase-like protein YP_002809611.1 901819 D 579112 CDS YP_002809612.1 227081061 7772122 complement(902399..902701) 1 NC_012578.1 hypothetical protein 902701 7772122 VCM66_0842 Vibrio cholerae M66-2 hypothetical protein YP_002809612.1 902399 R 579112 CDS YP_002809613.1 227081062 7772123 complement(902705..903742) 1 NC_012578.1 hypothetical protein 903742 7772123 VCM66_0843 Vibrio cholerae M66-2 hypothetical protein YP_002809613.1 902705 R 579112 CDS YP_002809614.1 227081063 7772124 903831..904142 1 NC_012578.1 hypothetical protein 904142 7772124 VCM66_0844 Vibrio cholerae M66-2 hypothetical protein YP_002809614.1 903831 D 579112 CDS YP_002809615.1 227081064 7772125 904143..904877 1 NC_012578.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 904877 7772125 VCM66_0845 Vibrio cholerae M66-2 tRNA pseudouridine synthase C YP_002809615.1 904143 D 579112 CDS YP_002809616.1 227081065 7772126 complement(904975..906855) 1 NC_012578.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 906855 dxs 7772126 dxs Vibrio cholerae M66-2 1-deoxy-D-xylulose-5-phosphate synthase YP_002809616.1 904975 R 579112 CDS YP_002809617.1 227081066 7772127 complement(906875..907759) 1 NC_012578.1 geranyltranstransferase 907759 ispA 7772127 ispA Vibrio cholerae M66-2 geranyltranstransferase YP_002809617.1 906875 R 579112 CDS YP_002809618.1 227081067 7772128 complement(907801..908043) 1 NC_012578.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 908043 xseB 7772128 xseB Vibrio cholerae M66-2 exodeoxyribonuclease VII small subunit YP_002809618.1 907801 R 579112 CDS YP_002809619.1 227081068 7772129 908358..909122 1 NC_012578.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; flagellar motor protein PomA 909122 pomA 7772129 pomA Vibrio cholerae M66-2 flagellar motor protein PomA YP_002809619.1 908358 D 579112 CDS YP_002809620.1 227081069 7772130 909134..910090 1 NC_012578.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar motor protein MotB 910090 motB 7772130 motB Vibrio cholerae M66-2 flagellar motor protein MotB YP_002809620.1 909134 D 579112 CDS YP_002809621.1 227081070 7772131 910298..911845 1 NC_012578.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 911845 thiI 7772131 thiI Vibrio cholerae M66-2 thiamine biosynthesis protein ThiI YP_002809621.1 910298 D 579112 CDS YP_002809622.1 227081071 7772132 912428..913348 1 NC_012578.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 913348 7772132 VCM66_0853 Vibrio cholerae M66-2 DNA-binding transcriptional activator GcvA YP_002809622.1 912428 D 579112 CDS YP_002809623.1 227081072 7772133 913370..913756 1 NC_012578.1 hypothetical protein 913756 7772133 VCM66_0854 Vibrio cholerae M66-2 hypothetical protein YP_002809623.1 913370 D 579112 CDS YP_002809624.1 227081073 7772134 complement(913787..914638) 1 NC_012578.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 914638 xni 7772134 xni Vibrio cholerae M66-2 exonuclease IX YP_002809624.1 913787 R 579112 CDS YP_002809625.1 227081074 7772135 complement(914677..916050) 1 NC_012578.1 hypothetical protein 916050 7772135 VCM66_0856 Vibrio cholerae M66-2 hypothetical protein YP_002809625.1 914677 R 579112 CDS YP_002809626.1 227081075 7772136 complement(916255..917829) 1 NC_012578.1 GGDEF family protein 917829 7772136 VCM66_0857 Vibrio cholerae M66-2 GGDEF family protein YP_002809626.1 916255 R 579112 CDS YP_002809627.1 227081076 7772137 complement(917931..920192) 1 NC_012578.1 hypothetical protein 920192 7772137 VCM66_0858 Vibrio cholerae M66-2 hypothetical protein YP_002809627.1 917931 R 579112 CDS YP_002809628.1 227081077 7772138 complement(920207..921070) 1 NC_012578.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 921070 queF 7772138 queF Vibrio cholerae M66-2 7-cyano-7-deazaguanine reductase YP_002809628.1 920207 R 579112 CDS YP_002809629.1 227081078 7772139 921101..921697 1 NC_012578.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 921697 syd 7772139 syd Vibrio cholerae M66-2 SecY interacting protein Syd YP_002809629.1 921101 D 579112 CDS YP_002809630.1 227081079 7772140 921699..922475 1 NC_012578.1 hypothetical protein 922475 7772140 VCM66_0861 Vibrio cholerae M66-2 hypothetical protein YP_002809630.1 921699 D 579112 CDS YP_002809631.1 227081080 7772141 complement(922608..923435) 1 NC_012578.1 DL-methionine transporter substrate-binding subunit 923435 metQ 7772141 metQ Vibrio cholerae M66-2 DL-methionine transporter substrate-binding subunit YP_002809631.1 922608 R 579112 CDS YP_002809632.1 227081081 7772142 complement(923454..924131) 1 NC_012578.1 ABC transporter permease 924131 7772142 VCM66_0863 Vibrio cholerae M66-2 ABC transporter permease YP_002809632.1 923454 R 579112 CDS YP_002809633.1 227081082 7772143 complement(924121..925155) 1 NC_012578.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 925155 metN 7772143 metN Vibrio cholerae M66-2 DL-methionine transporter ATP-binding subunit YP_002809633.1 924121 R 579112 CDS YP_002809634.1 227081083 7772144 925391..925951 1 NC_012578.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 925951 7772144 VCM66_0865 Vibrio cholerae M66-2 D,D-heptose 1,7-bisphosphate phosphatase YP_002809634.1 925391 D 579112 CDS YP_002809635.1 227081084 7772145 926016..926966 1 NC_012578.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 926966 treR 7772145 treR Vibrio cholerae M66-2 trehalose repressor YP_002809635.1 926016 D 579112 CDS YP_002809636.1 227081085 7772146 927203..928639 1 NC_012578.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 928639 treB 7772146 treB Vibrio cholerae M66-2 PTS system trehalose(maltose)-specific transporter subunits IIBC YP_002809636.1 927203 D 579112 CDS YP_002809637.1 227081086 7772147 928719..930407 1 NC_012578.1 trehalose-6-phosphate hydrolase 930407 treC 7772147 treC Vibrio cholerae M66-2 trehalose-6-phosphate hydrolase YP_002809637.1 928719 D 579112 CDS YP_002809638.1 227081087 7774075 931182..931277 1 NC_012578.1 hypothetical protein 931277 7774075 VCM66_0869 Vibrio cholerae M66-2 hypothetical protein YP_002809638.1 931182 D 579112 CDS YP_002809639.1 227081088 7772149 931464..932522 1 NC_012578.1 Multidrug resistance protein mdtA 932522 7772149 VCM66_0870 Vibrio cholerae M66-2 Multidrug resistance protein mdtA YP_002809639.1 931464 D 579112 CDS YP_002809640.1 227081089 7772150 932522..935632 1 NC_012578.1 putative multidrug resistance protein 935632 7772150 VCM66_0871 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002809640.1 932522 D 579112 CDS YP_002809641.1 227081090 7772151 935687..935797 1 NC_012578.1 hypothetical protein 935797 7772151 VCM66_0872 Vibrio cholerae M66-2 hypothetical protein YP_002809641.1 935687 D 579112 CDS YP_002809642.1 227081091 7772152 936059..936559 1 NC_012578.1 phosphotyrosine protein phosphatase 936559 7772152 VCM66_0873 Vibrio cholerae M66-2 phosphotyrosine protein phosphatase YP_002809642.1 936059 D 579112 CDS YP_002809643.1 227081092 7772153 936872..937990 1 NC_012578.1 UDP-N-acetylglucosamine 2-epimerase 937990 wecB 7772153 wecB Vibrio cholerae M66-2 UDP-N-acetylglucosamine 2-epimerase YP_002809643.1 936872 D 579112 CDS YP_002809644.1 227081093 7772154 938010..939251 1 NC_012578.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 939251 wecC 7772154 wecC Vibrio cholerae M66-2 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002809644.1 938010 D 579112 CDS YP_002809645.1 227081094 7772155 939248..939802 1 NC_012578.1 serine acetyltransferase-like protein 939802 7772155 VCM66_0876 Vibrio cholerae M66-2 serine acetyltransferase-like protein YP_002809645.1 939248 D 579112 CDS YP_002809646.1 227081095 7772156 939799..940947 1 NC_012578.1 putative exopolysaccharide biosynthesis protein 940947 7772156 VCM66_0877 Vibrio cholerae M66-2 putative exopolysaccharide biosynthesis protein YP_002809646.1 939799 D 579112 CDS YP_002809647.1 227081096 7772157 940944..942353 1 NC_012578.1 putative polysaccharide export protein 942353 7772157 VCM66_0878 Vibrio cholerae M66-2 putative polysaccharide export protein YP_002809647.1 940944 D 579112 CDS YP_002809648.1 227081097 7772158 942350..943570 1 NC_012578.1 hypothetical protein 943570 7772158 VCM66_0879 Vibrio cholerae M66-2 hypothetical protein YP_002809648.1 942350 D 579112 CDS YP_002809649.1 227081098 7772159 943581..944012 1 NC_012578.1 serine acetyltransferase-like protein 944012 7772159 VCM66_0880 Vibrio cholerae M66-2 serine acetyltransferase-like protein YP_002809649.1 943581 D 579112 CDS YP_002809650.1 227081099 7772160 944012..945352 1 NC_012578.1 putative capK protein 945352 7772160 VCM66_0881 Vibrio cholerae M66-2 putative capK protein YP_002809650.1 944012 D 579112 CDS YP_002809651.1 227081100 7772161 945328..946425 1 NC_012578.1 putative polysaccharide biosynthesis protein 946425 7772161 VCM66_0882 Vibrio cholerae M66-2 putative polysaccharide biosynthesis protein YP_002809651.1 945328 D 579112 CDS YP_002809652.1 227081101 7772162 946422..947594 1 NC_012578.1 hypothetical protein 947594 7772162 VCM66_0883 Vibrio cholerae M66-2 hypothetical protein YP_002809652.1 946422 D 579112 CDS YP_002809653.1 227081102 7772163 947584..948336 1 NC_012578.1 UDP-N-acetyl-D-mannosamine transferase 948336 cpsF 7772163 cpsF Vibrio cholerae M66-2 UDP-N-acetyl-D-mannosamine transferase YP_002809653.1 947584 D 579112 CDS YP_002809654.1 227081103 7772164 948532..949347 1 NC_012578.1 hypothetical protein 949347 7772164 VCM66_0885 Vibrio cholerae M66-2 hypothetical protein YP_002809654.1 948532 D 579112 CDS YP_002809655.1 227081104 7772165 complement(949553..950779) 1 NC_012578.1 hypothetical protein 950779 7772165 VCM66_0886 Vibrio cholerae M66-2 hypothetical protein YP_002809655.1 949553 R 579112 CDS YP_002809656.1 227081105 7772166 951043..953916 1 NC_012578.1 hemolysin-like protein 953916 7772166 VCM66_0887 Vibrio cholerae M66-2 hemolysin-like protein YP_002809656.1 951043 D 579112 CDS YP_002809657.1 227081106 7772167 complement(954071..955387) 1 NC_012578.1 hypothetical protein 955387 7772167 VCM66_0888 Vibrio cholerae M66-2 hypothetical protein YP_002809657.1 954071 R 579112 CDS YP_002809658.1 227081107 7772168 complement(955563..956168) 1 NC_012578.1 hypothetical protein 956168 7772168 VCM66_0889 Vibrio cholerae M66-2 hypothetical protein YP_002809658.1 955563 R 579112 CDS YP_002809659.1 227081108 7772169 956658..958055 1 NC_012578.1 putative capsular polysaccharide biosynthesis glycosyltransferase 958055 7772169 VCM66_0890 Vibrio cholerae M66-2 putative capsular polysaccharide biosynthesis glycosyltransferase YP_002809659.1 956658 D 579112 CDS YP_002809660.1 227081109 7772170 958126..959322 1 NC_012578.1 hypothetical protein 959322 7772170 VCM66_0891 Vibrio cholerae M66-2 hypothetical protein YP_002809660.1 958126 D 579112 CDS YP_002809661.1 227081110 7772171 959326..959853 1 NC_012578.1 polysaccharide export-like protein 959853 7772171 VCM66_0892 Vibrio cholerae M66-2 polysaccharide export-like protein YP_002809661.1 959326 D 579112 CDS YP_002809662.1 227081111 7772172 959878..962091 1 NC_012578.1 putative exopolysaccharide biosynthesis protein 962091 7772172 VCM66_0893 Vibrio cholerae M66-2 putative exopolysaccharide biosynthesis protein YP_002809662.1 959878 D 579112 CDS YP_002809663.1 227081112 7772173 962088..962795 1 NC_012578.1 hypothetical protein 962795 7772173 VCM66_0894 Vibrio cholerae M66-2 hypothetical protein YP_002809663.1 962088 D 579112 CDS YP_002809664.1 227081113 7772174 962774..963208 1 NC_012578.1 hypothetical protein 963208 7772174 VCM66_0895 Vibrio cholerae M66-2 hypothetical protein YP_002809664.1 962774 D 579112 CDS YP_002809665.1 227081114 7772175 complement(963364..963960) 1 NC_012578.1 hypothetical protein 963960 7772175 VCM66_0896 Vibrio cholerae M66-2 hypothetical protein YP_002809665.1 963364 R 579112 CDS YP_002809666.1 227081115 7772176 964244..965551 1 NC_012578.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 965551 glyA 7772176 glyA Vibrio cholerae M66-2 serine hydroxymethyltransferase YP_002809666.1 964244 D 579112 CDS YP_002809667.1 227081116 7772177 complement(965716..966069) 1 NC_012578.1 hypothetical protein 966069 7772177 VCM66_0898 Vibrio cholerae M66-2 hypothetical protein YP_002809667.1 965716 R 579112 CDS YP_002809668.1 227081117 7772178 complement(966238..967203) 1 NC_012578.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 967203 lipA 7772178 lipA Vibrio cholerae M66-2 lipoyl synthase YP_002809668.1 966238 R 579112 CDS YP_002809669.1 227081118 7772179 complement(967196..967855) 1 NC_012578.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 967855 lipB 7772179 lipB Vibrio cholerae M66-2 lipoate-protein ligase B YP_002809669.1 967196 R 579112 CDS YP_002809670.1 227081119 7772180 complement(968034..968312) 1 NC_012578.1 hypothetical protein 968312 7772180 VCM66_0901 Vibrio cholerae M66-2 hypothetical protein YP_002809670.1 968034 R 579112 CDS YP_002809671.1 227081120 7772181 968334..968501 1 NC_012578.1 hypothetical protein 968501 7772181 VCM66_0902 Vibrio cholerae M66-2 hypothetical protein YP_002809671.1 968334 D 579112 CDS YP_002809672.1 227081121 7772182 complement(968460..969635) 1 NC_012578.1 D-alanyl-D-alanine carboxypeptidase 969635 dacA-1 7772182 dacA-1 Vibrio cholerae M66-2 D-alanyl-D-alanine carboxypeptidase YP_002809672.1 968460 R 579112 CDS YP_002809673.1 227081122 7772183 complement(969727..970518) 1 NC_012578.1 putative rare lipoprotein A 970518 7772183 VCM66_0904 Vibrio cholerae M66-2 putative rare lipoprotein A YP_002809673.1 969727 R 579112 CDS YP_002809674.1 227081123 7772184 complement(970518..971639) 1 NC_012578.1 rod shape-determining protein RodA 971639 rodA 7772184 rodA Vibrio cholerae M66-2 rod shape-determining protein RodA YP_002809674.1 970518 R 579112 CDS YP_002809675.1 227081124 7772185 complement(971636..973552) 1 NC_012578.1 penicillin-binding protein 2 973552 mrdA 7772185 mrdA Vibrio cholerae M66-2 penicillin-binding protein 2 YP_002809675.1 971636 R 579112 CDS YP_002809676.1 227081125 7772186 complement(973559..974029) 1 NC_012578.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 974029 7772186 VCM66_0907 Vibrio cholerae M66-2 rRNA large subunit methyltransferase YP_002809676.1 973559 R 579112 CDS YP_002809677.1 227081126 7772187 complement(974032..974349) 1 NC_012578.1 hypothetical protein 974349 7772187 VCM66_0908 Vibrio cholerae M66-2 hypothetical protein YP_002809677.1 974032 R 579112 CDS YP_002809678.1 227081127 7772188 complement(974418..975446) 1 NC_012578.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 975446 holA 7772188 holA Vibrio cholerae M66-2 DNA polymerase III subunit delta YP_002809678.1 974418 R 579112 CDS YP_002809679.1 227081128 7772189 complement(975452..976093) 1 NC_012578.1 rare lipoprotein B 976093 rlpB 7772189 rlpB Vibrio cholerae M66-2 rare lipoprotein B YP_002809679.1 975452 R 579112 CDS YP_002809680.1 227081129 7772190 complement(976109..976213) 1 NC_012578.1 hypothetical protein 976213 7772190 VCM66_0911 Vibrio cholerae M66-2 hypothetical protein YP_002809680.1 976109 R 579112 CDS YP_002809681.1 227081130 7772191 complement(976243..978927) 1 NC_012578.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 978927 leuS 7772191 leuS Vibrio cholerae M66-2 leucyl-tRNA synthetase YP_002809681.1 976243 R 579112 CDS YP_002809682.1 227081131 7772192 978949..979419 1 NC_012578.1 hypothetical protein 979419 7772192 VCM66_0913 Vibrio cholerae M66-2 hypothetical protein YP_002809682.1 978949 D 579112 CDS YP_002809683.1 227081132 7772193 complement(979475..980992) 1 NC_012578.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 980992 lnt 7772193 lnt Vibrio cholerae M66-2 apolipoprotein N-acyltransferase YP_002809683.1 979475 R 579112 CDS YP_002809684.1 227081133 7772194 complement(981033..981908) 1 NC_012578.1 putative hemolysin 981908 7772194 VCM66_0915 Vibrio cholerae M66-2 putative hemolysin YP_002809684.1 981033 R 579112 CDS YP_002809685.1 227081134 7772195 complement(981978..982442) 1 NC_012578.1 putative metalloprotease 982442 7772195 VCM66_0916 Vibrio cholerae M66-2 putative metalloprotease YP_002809685.1 981978 R 579112 CDS YP_002809686.1 227081135 7772196 complement(982439..983542) 1 NC_012578.1 phoH family protein 983542 7772196 VCM66_0917 Vibrio cholerae M66-2 phoH family protein YP_002809686.1 982439 R 579112 CDS YP_002809687.1 227081136 7772197 complement(983610..985034) 1 NC_012578.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 985034 7772197 VCM66_0918 Vibrio cholerae M66-2 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002809687.1 983610 R 579112 CDS YP_002809688.1 227081137 7772198 985258..986451 1 NC_012578.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 986451 7772198 VCM66_0919 Vibrio cholerae M66-2 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002809688.1 985258 D 579112 CDS YP_002809689.1 227081138 7772199 complement(986576..987085) 1 NC_012578.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 987085 crr 7772199 crr Vibrio cholerae M66-2 PTS system glucose-specific transporter subunit YP_002809689.1 986576 R 579112 CDS YP_002809690.1 227081139 7772200 complement(987194..988915) 1 NC_012578.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 988915 ptsI 7772200 ptsI Vibrio cholerae M66-2 phosphoenolpyruvate-protein phosphotransferase YP_002809690.1 987194 R 579112 CDS YP_002809691.1 227081140 7772201 complement(989049..989306) 1 NC_012578.1 phosphocarrier protein HPr 989306 ptsH 7772201 ptsH Vibrio cholerae M66-2 phosphocarrier protein HPr YP_002809691.1 989049 R 579112 CDS YP_002809692.1 227081141 7772202 complement(989391..989600) 1 NC_012578.1 hypothetical protein 989600 7772202 VCM66_0923 Vibrio cholerae M66-2 hypothetical protein YP_002809692.1 989391 R 579112 CDS YP_002809693.1 227081142 7772203 complement(989604..990572) 1 NC_012578.1 cysteine synthase A 990572 cysK 7772203 cysK Vibrio cholerae M66-2 cysteine synthase A YP_002809693.1 989604 R 579112 CDS YP_002809694.1 227081143 7772204 complement(990695..991447) 1 NC_012578.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 991447 cysZ 7772204 cysZ Vibrio cholerae M66-2 putative sulfate transport protein CysZ YP_002809694.1 990695 R 579112 CDS YP_002809695.1 227081144 7772205 991677..992552 1 NC_012578.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 992552 zipA 7772205 zipA Vibrio cholerae M66-2 cell division protein ZipA YP_002809695.1 991677 D 579112 CDS YP_002809696.1 227081145 7772206 992685..994694 1 NC_012578.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 994694 ligA 7772206 ligA Vibrio cholerae M66-2 NAD-dependent DNA ligase LigA YP_002809696.1 992685 D 579112 CDS YP_002809697.1 227081146 7772207 995326..996375 1 NC_012578.1 putative porin 996375 7772207 VCM66_0928 Vibrio cholerae M66-2 putative porin YP_002809697.1 995326 D 579112 CDS YP_002809698.1 227081147 7772208 996452..997267 1 NC_012578.1 hypothetical protein 997267 7772208 VCM66_0929 Vibrio cholerae M66-2 hypothetical protein YP_002809698.1 996452 D 579112 CDS YP_002809699.1 227081148 7772209 997328..997747 1 NC_012578.1 MerR family transcriptional regulator 997747 7772209 VCM66_0930 Vibrio cholerae M66-2 MerR family transcriptional regulator YP_002809699.1 997328 D 579112 CDS YP_002809700.1 227081149 7772210 complement(997791..998360) 1 NC_012578.1 putative Inner membrane protein 998360 7772210 VCM66_0931 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809700.1 997791 R 579112 CDS YP_002809701.1 227081150 7772211 complement(998248..999168) 1 NC_012578.1 hypothetical protein 999168 7772211 VCM66_0932 Vibrio cholerae M66-2 hypothetical protein YP_002809701.1 998248 R 579112 CDS YP_002809702.1 227081151 7772212 complement(999599..1000519) 1 NC_012578.1 hypothetical protein 1000519 7772212 VCM66_0933 Vibrio cholerae M66-2 hypothetical protein YP_002809702.1 999599 R 579112 CDS YP_002809703.1 227081152 7772213 complement(1000691..1000807) 1 NC_012578.1 hypothetical protein 1000807 7772213 VCM66_0934 Vibrio cholerae M66-2 hypothetical protein YP_002809703.1 1000691 R 579112 CDS YP_002809704.1 227081153 7772214 complement(1000882..1001709) 1 NC_012578.1 short chain dehydrogenase 1001709 7772214 VCM66_0935 Vibrio cholerae M66-2 short chain dehydrogenase YP_002809704.1 1000882 R 579112 CDS YP_002809705.1 227081154 7772215 complement(1001752..1002666) 1 NC_012578.1 rcp protein 1002666 rcp 7772215 rcp Vibrio cholerae M66-2 rcp protein YP_002809705.1 1001752 R 579112 CDS YP_002809706.1 227081155 7772216 1003060..1003629 1 NC_012578.1 phosphodiesterase 1003629 7772216 VCM66_0937 Vibrio cholerae M66-2 phosphodiesterase YP_002809706.1 1003060 D 579112 CDS YP_002809707.1 227081156 7772217 complement(1003710..1004003) 1 NC_012578.1 selenoprotein W-like protein 1004003 7772217 VCM66_0938 Vibrio cholerae M66-2 selenoprotein W-like protein YP_002809707.1 1003710 R 579112 CDS YP_002809708.1 227081157 7772218 complement(1004044..1004565) 1 NC_012578.1 regulatory protein ToxS 1004565 toxS 7772218 toxS Vibrio cholerae M66-2 regulatory protein ToxS YP_002809708.1 1004044 R 579112 CDS YP_002809709.1 227081158 7772219 complement(1004575..1005459) 1 NC_012578.1 cholera toxin transcriptional activator 1005459 toxR 7772219 toxR Vibrio cholerae M66-2 cholera toxin transcriptional activator YP_002809709.1 1004575 R 579112 CDS YP_002809710.1 227081159 7772220 1005687..1007594 1 NC_012578.1 molecular chaperone; heat shock protein 90 1007594 htpG 7772220 htpG Vibrio cholerae M66-2 heat shock protein 90 YP_002809710.1 1005687 D 579112 CDS YP_002809711.1 227081160 7772221 1007929..1008573 1 NC_012578.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1008573 adk 7772221 adk Vibrio cholerae M66-2 adenylate kinase YP_002809711.1 1007929 D 579112 CDS YP_002809712.1 227081161 7772222 1008688..1009662 1 NC_012578.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1009662 hemH 7772222 hemH Vibrio cholerae M66-2 ferrochelatase YP_002809712.1 1008688 D 579112 CDS YP_002809713.1 227081162 7772223 complement(1009762..1011306) 1 NC_012578.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1011306 tppB 7772223 tppB Vibrio cholerae M66-2 putative tripeptide transporter permease YP_002809713.1 1009762 R 579112 CDS YP_002809714.1 227081163 7772224 1011568..1011717 1 NC_012578.1 hypothetical protein 1011717 7772224 VCM66_0945 Vibrio cholerae M66-2 hypothetical protein YP_002809714.1 1011568 D 579112 CDS YP_002809715.1 227081164 7772225 1011751..1012248 1 NC_012578.1 transcriptional activator RfaH 1012248 rfaH 7772225 rfaH Vibrio cholerae M66-2 transcriptional activator RfaH YP_002809715.1 1011751 D 579112 CDS YP_002809716.1 227081165 7772226 complement(1012396..1014060) 1 NC_012578.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 1014060 asnB 7772226 asnB Vibrio cholerae M66-2 asparagine synthetase B YP_002809716.1 1012396 R 579112 CDS YP_002809717.1 227081166 7772227 complement(1014256..1015842) 1 NC_012578.1 putative glutathione-regulated potassium-efflux system protein KefB 1015842 7772227 VCM66_0948 Vibrio cholerae M66-2 putative glutathione-regulated potassium-efflux system protein KefB YP_002809717.1 1014256 R 579112 CDS YP_002809718.1 227081167 7772228 complement(1015937..1017151) 1 NC_012578.1 N-acetylglucosamine repressor 1017151 nagC 7772228 nagC Vibrio cholerae M66-2 N-acetylglucosamine repressor YP_002809718.1 1015937 R 579112 CDS YP_002809719.1 227081168 7772229 complement(1017154..1018290) 1 NC_012578.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 1018290 nagA 7772229 nagA Vibrio cholerae M66-2 N-acetylglucosamine-6-phosphate deacetylase YP_002809719.1 1017154 R 579112 CDS YP_002809720.1 227081169 7772230 1018759..1020330 1 NC_012578.1 PTS system N-acetylglucosamine-specific transporter subunit IIABC 1020330 nagE 7772230 nagE Vibrio cholerae M66-2 PTS system N-acetylglucosamine-specific transporter subunit IIABC YP_002809720.1 1018759 D 579112 CDS YP_002809721.1 227081170 7772231 1020459..1020560 1 NC_012578.1 hypothetical protein 1020560 7772231 VCM66_0952 Vibrio cholerae M66-2 hypothetical protein YP_002809721.1 1020459 D 579112 CDS YP_002809722.1 227081171 7772232 1020578..1022248 1 NC_012578.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1022248 glnS 7772232 glnS Vibrio cholerae M66-2 glutaminyl-tRNA synthetase YP_002809722.1 1020578 D 579112 CDS YP_002809723.1 227081172 7772233 1022413..1027278 1 NC_012578.1 hypothetical protein 1027278 7772233 VCM66_0954 Vibrio cholerae M66-2 hypothetical protein YP_002809723.1 1022413 D 579112 CDS YP_002809724.1 227081173 7772234 1027400..1028194 1 NC_012578.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1028194 truA 7772234 truA Vibrio cholerae M66-2 tRNA pseudouridine synthase A YP_002809724.1 1027400 D 579112 CDS YP_002809725.1 227081174 7772235 1028368..1029294 1 NC_012578.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1029294 accD 7772235 accD Vibrio cholerae M66-2 acetyl-CoA carboxylase subunit beta YP_002809725.1 1028368 D 579112 CDS YP_002809726.1 227081175 7772236 1029339..1030604 1 NC_012578.1 folylpolyglutamate synthase/dihydrofolate synthase 1030604 folC 7772236 folC Vibrio cholerae M66-2 folylpolyglutamate synthase/dihydrofolate synthase YP_002809726.1 1029339 D 579112 CDS YP_002809727.1 227081176 7772237 1030605..1031201 1 NC_012578.1 dedD protein 1031201 dedD 7772237 dedD Vibrio cholerae M66-2 dedD protein YP_002809727.1 1030605 D 579112 CDS YP_002809728.1 227081177 7772238 1031264..1031755 1 NC_012578.1 bacteriocin production protein 1031755 7772238 VCM66_0959 Vibrio cholerae M66-2 bacteriocin production protein YP_002809728.1 1031264 D 579112 CDS YP_002809729.1 227081178 7772239 1031788..1033302 1 NC_012578.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1033302 purF 7772239 purF Vibrio cholerae M66-2 amidophosphoribosyltransferase YP_002809729.1 1031788 D 579112 CDS YP_002809730.1 227081179 7772240 complement(1033430..1034755) 1 NC_012578.1 hypothetical protein 1034755 7772240 VCM66_0961 Vibrio cholerae M66-2 hypothetical protein YP_002809730.1 1033430 R 579112 CDS YP_002809731.1 227081180 7772241 complement(1034856..1035587) 1 NC_012578.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1035587 rnt 7772241 rnt Vibrio cholerae M66-2 ribonuclease T YP_002809731.1 1034856 R 579112 CDS YP_002809732.1 227081181 7772242 complement(1035600..1035743) 1 NC_012578.1 hypothetical protein 1035743 7772242 VCM66_0963 Vibrio cholerae M66-2 hypothetical protein YP_002809732.1 1035600 R 579112 CDS YP_002809733.1 227081182 7772243 1035804..1036688 1 NC_012578.1 sodium-type flagellar protein MotY 1036688 motY 7772243 motY Vibrio cholerae M66-2 sodium-type flagellar protein MotY YP_002809733.1 1035804 D 579112 CDS YP_002809734.1 227081183 7772244 complement(1036737..1037177) 1 NC_012578.1 hypothetical protein 1037177 7772244 VCM66_0965 Vibrio cholerae M66-2 hypothetical protein YP_002809734.1 1036737 R 579112 CDS YP_002809735.1 227081184 7772245 complement(1037336..1037890) 1 NC_012578.1 lactoylglutathione lyase 1037890 gloA 7772245 gloA Vibrio cholerae M66-2 lactoylglutathione lyase YP_002809735.1 1037336 R 579112 CDS YP_002809736.1 227081185 7772246 complement(1037793..1038434) 1 NC_012578.1 endonuclease III 1038434 nth 7772246 nth Vibrio cholerae M66-2 endonuclease III YP_002809736.1 1037793 R 579112 CDS YP_002809737.1 227081186 7772247 complement(1038461..1039153) 1 NC_012578.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1039153 7772247 VCM66_0968 Vibrio cholerae M66-2 electron transport complex RsxE subunit YP_002809737.1 1038461 R 579112 CDS YP_002809738.1 227081187 7772248 complement(1039155..1039784) 1 NC_012578.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1039784 7772248 VCM66_0969 Vibrio cholerae M66-2 electron transport complex protein RnfG YP_002809738.1 1039155 R 579112 CDS YP_002809739.1 227081188 7772249 complement(1039796..1040842) 1 NC_012578.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1040842 rnfD 7772249 rnfD Vibrio cholerae M66-2 electron transport complex protein RnfD YP_002809739.1 1039796 R 579112 CDS YP_002809740.1 227081189 7772250 complement(1040842..1043247) 1 NC_012578.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1043247 7772250 VCM66_0971 Vibrio cholerae M66-2 electron transport complex protein RnfC YP_002809740.1 1040842 R 579112 CDS YP_002809741.1 227081190 7772251 complement(1043175..1043762) 1 NC_012578.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1043762 7772251 VCM66_0972 Vibrio cholerae M66-2 electron transport complex protein RnfB YP_002809741.1 1043175 R 579112 CDS YP_002809742.1 227081191 7772252 complement(1043762..1044403) 1 NC_012578.1 Na(+)-translocating NADH-quinone reductase subunit E 1044403 7772252 VCM66_0973 Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit E YP_002809742.1 1043762 R 579112 CDS YP_002809743.1 227081192 7774003 1045225..1047255 1 NC_012578.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1047255 uvrB 7774003 uvrB Vibrio cholerae M66-2 excinuclease ABC subunit B YP_002809743.1 1045225 D 579112 CDS YP_002809744.1 227081193 7772254 complement(1047193..1047393) 1 NC_012578.1 hypothetical protein 1047393 7772254 VCM66_0975 Vibrio cholerae M66-2 hypothetical protein YP_002809744.1 1047193 R 579112 CDS YP_002809745.1 227081194 7772255 1047686..1049053 1 NC_012578.1 LuxO repressor protein 1049053 luxO 7772255 luxO Vibrio cholerae M66-2 LuxO repressor protein YP_002809745.1 1047686 D 579112 CDS YP_002809746.1 227081195 7772256 1049057..1049398 1 NC_012578.1 phosphorelay protein 1049398 luxU 7772256 luxU Vibrio cholerae M66-2 phosphorelay protein YP_002809746.1 1049057 D 579112 CDS YP_002809747.1 227081196 7772257 complement(1049387..1050277) 1 NC_012578.1 hypothetical protein 1050277 7772257 VCM66_0978 Vibrio cholerae M66-2 hypothetical protein YP_002809747.1 1049387 R 579112 CDS YP_002809748.1 227081197 7772258 1050568..1051572 1 NC_012578.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1051572 moaA 7772258 moaA Vibrio cholerae M66-2 molybdenum cofactor biosynthesis protein A YP_002809748.1 1050568 D 579112 CDS YP_002809749.1 227081198 7772259 1051632..1052144 1 NC_012578.1 molybdenum cofactor biosynthesis protein B 1052144 moaB 7772259 moaB Vibrio cholerae M66-2 molybdenum cofactor biosynthesis protein B YP_002809749.1 1051632 D 579112 CDS YP_002809750.1 227081199 7772260 1052152..1052634 1 NC_012578.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1052634 moaC 7772260 moaC Vibrio cholerae M66-2 molybdenum cofactor biosynthesis protein MoaC YP_002809750.1 1052152 D 579112 CDS YP_002809751.1 227081200 7772261 1052631..1052876 1 NC_012578.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1052876 moaD 7772261 moaD Vibrio cholerae M66-2 molybdopterin synthase small subunit YP_002809751.1 1052631 D 579112 CDS YP_002809752.1 227081201 7772262 1052878..1053330 1 NC_012578.1 molybdenum cofactor biosynthesis protein E 1053330 moaE 7772262 moaE Vibrio cholerae M66-2 molybdenum cofactor biosynthesis protein E YP_002809752.1 1052878 D 579112 CDS YP_002809753.1 227081202 7772263 complement(1053345..1054319) 1 NC_012578.1 GGDEF family protein 1054319 7772263 VCM66_0984 Vibrio cholerae M66-2 GGDEF family protein YP_002809753.1 1053345 R 579112 CDS YP_002809754.1 227081203 7772264 complement(1054374..1054466) 1 NC_012578.1 hypothetical protein 1054466 7772264 VCM66_0985 Vibrio cholerae M66-2 hypothetical protein YP_002809754.1 1054374 R 579112 CDS YP_002809755.1 227081204 7772265 1054524..1054964 1 NC_012578.1 inosine monophosphate dehydrogenase-like protein 1054964 7772265 VCM66_0986 Vibrio cholerae M66-2 inosine monophosphate dehydrogenase-like protein YP_002809755.1 1054524 D 579112 CDS YP_002809756.1 227081205 7772266 complement(1054897..1055094) 1 NC_012578.1 hypothetical protein 1055094 7772266 VCM66_0987 Vibrio cholerae M66-2 hypothetical protein YP_002809756.1 1054897 R 579112 CDS YP_002809757.1 227081206 7772267 1055077..1057383 1 NC_012578.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 1057383 zntA 7772267 zntA Vibrio cholerae M66-2 zinc/cadmium/mercury/lead-transporting ATPase YP_002809757.1 1055077 D 579112 CDS YP_002809758.1 227081207 7772268 1057829..1058605 1 NC_012578.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 1058605 udp-1 7772268 udp-1 Vibrio cholerae M66-2 uridine phosphorylase YP_002809758.1 1057829 D 579112 CDS YP_002809759.1 227081208 7772269 complement(1058678..1059571) 1 NC_012578.1 hypothetical protein 1059571 7772269 VCM66_0990 Vibrio cholerae M66-2 hypothetical protein YP_002809759.1 1058678 R 579112 CDS YP_002809760.1 227081209 7772270 complement(1059797..1061992) 1 NC_012578.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1061992 metG 7772270 metG Vibrio cholerae M66-2 methionyl-tRNA synthetase YP_002809760.1 1059797 R 579112 CDS YP_002809761.1 227081210 7772271 1061934..1063082 1 NC_012578.1 mrp protein 1063082 mrp 7772271 mrp Vibrio cholerae M66-2 mrp protein YP_002809761.1 1061934 D 579112 CDS YP_002809762.1 227081211 7772272 1063241..1063900 1 NC_012578.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1063900 udk 7772272 udk Vibrio cholerae M66-2 uridine kinase YP_002809762.1 1063241 D 579112 CDS YP_002809763.1 227081212 7772273 1063998..1066109 1 NC_012578.1 asmA protein 1066109 asmA 7772273 asmA Vibrio cholerae M66-2 asmA protein YP_002809763.1 1063998 D 579112 CDS YP_002809764.1 227081213 7772274 complement(1066181..1066786) 1 NC_012578.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1066786 cobA 7772274 cobA Vibrio cholerae M66-2 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002809764.1 1066181 R 579112 CDS YP_002809765.1 227081214 7772275 1066872..1067339 1 NC_012578.1 phosphotyrosine protein phosphatase 1067339 7772275 VCM66_0996 Vibrio cholerae M66-2 phosphotyrosine protein phosphatase YP_002809765.1 1066872 D 579112 CDS YP_002809766.1 227081215 7772276 complement(1067366..1068664) 1 NC_012578.1 long-chain fatty acid transport protein 1068664 fadL-1 7772276 fadL-1 Vibrio cholerae M66-2 long-chain fatty acid transport protein YP_002809766.1 1067366 R 579112 CDS YP_002809767.1 227081216 7772277 complement(1068967..1070253) 1 NC_012578.1 long-chain fatty acid transport protein 1070253 fadL-2 7772277 fadL-2 Vibrio cholerae M66-2 long-chain fatty acid transport protein YP_002809767.1 1068967 R 579112 CDS YP_002809768.1 227081217 7772278 complement(1070513..1071274) 1 NC_012578.1 hypothetical protein 1071274 7772278 VCM66_0999 Vibrio cholerae M66-2 hypothetical protein YP_002809768.1 1070513 R 579112 CDS YP_002809769.1 227081218 7772279 complement(1071237..1071803) 1 NC_012578.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1071803 7772279 VCM66_1000 Vibrio cholerae M66-2 RNA polymerase sigma factor YP_002809769.1 1071237 R 579112 CDS YP_002809770.1 227081219 7772280 1072184..1073638 1 NC_012578.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 1073638 fadI 7772280 fadI Vibrio cholerae M66-2 3-ketoacyl-CoA thiolase YP_002809770.1 1072184 D 579112 CDS YP_002809771.1 227081220 7772281 1073590..1075764 1 NC_012578.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 1075764 fadJ 7772281 fadJ Vibrio cholerae M66-2 multifunctional fatty acid oxidation complex subunit alpha YP_002809771.1 1073590 D 579112 CDS YP_002809772.1 227081221 7772282 1075890..1076438 1 NC_012578.1 hypothetical protein 1076438 7772282 VCM66_1003 Vibrio cholerae M66-2 hypothetical protein YP_002809772.1 1075890 D 579112 CDS YP_002809773.1 227081222 7772283 complement(1076517..1077416) 1 NC_012578.1 LysR family transcriptional regulator 1077416 7772283 VCM66_1004 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002809773.1 1076517 R 579112 CDS YP_002809774.1 227081223 7772284 1077625..1078731 1 NC_012578.1 response regulator 1078731 7772284 VCM66_1005 Vibrio cholerae M66-2 response regulator YP_002809774.1 1077625 D 579112 CDS YP_002809775.1 227081224 7772285 1078901..1079032 1 NC_012578.1 hypothetical protein 1079032 7772285 VCM66_1006 Vibrio cholerae M66-2 hypothetical protein YP_002809775.1 1078901 D 579112 CDS YP_002809776.1 227081225 7772286 1079032..1079430 1 NC_012578.1 putative Inner membrane protein 1079430 7772286 VCM66_1007 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809776.1 1079032 D 579112 CDS YP_002809777.1 227081226 7772287 1079562..1080107 1 NC_012578.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1080107 apt 7772287 apt Vibrio cholerae M66-2 adenine phosphoribosyltransferase YP_002809777.1 1079562 D 579112 CDS YP_002809778.1 227081227 7772288 1080126..1082204 1 NC_012578.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1082204 dnaZX 7772288 dnaZX Vibrio cholerae M66-2 DNA polymerase III subunits gamma and tau YP_002809778.1 1080126 D 579112 CDS YP_002809779.1 227081228 7772289 1082242..1082604 1 NC_012578.1 hypothetical protein 1082604 7772289 VCM66_1010 Vibrio cholerae M66-2 hypothetical protein YP_002809779.1 1082242 D 579112 CDS YP_002809780.1 227081229 7772290 1082619..1083221 1 NC_012578.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1083221 recR 7772290 recR Vibrio cholerae M66-2 recombination protein RecR YP_002809780.1 1082619 D 579112 CDS YP_002809781.1 227081230 7772291 complement(1083331..1083582) 1 NC_012578.1 putative proteinase inhibitor 1083582 7772291 VCM66_1012 Vibrio cholerae M66-2 putative proteinase inhibitor YP_002809781.1 1083331 R 579112 CDS YP_002809782.1 227081231 7772292 1083717..1084154 1 NC_012578.1 hypothetical protein 1084154 7772292 VCM66_1013 Vibrio cholerae M66-2 hypothetical protein YP_002809782.1 1083717 D 579112 CDS YP_002809783.1 227081232 7772293 complement(1084248..1084991) 1 NC_012578.1 short chain dehydrogenase 1084991 7772293 VCM66_1014 Vibrio cholerae M66-2 short chain dehydrogenase YP_002809783.1 1084248 R 579112 CDS YP_002809784.1 227081233 7772294 1085141..1086211 1 NC_012578.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1086211 7772294 VCM66_1015 Vibrio cholerae M66-2 putative periplasmic protease YP_002809784.1 1085141 D 579112 CDS YP_002809785.1 227081234 7772295 complement(1086336..1087403) 1 NC_012578.1 cysteine synthase/cystathionine beta-synthase family protein 1087403 7772295 VCM66_1016 Vibrio cholerae M66-2 cysteine synthase/cystathionine beta-synthase family protein YP_002809785.1 1086336 R 579112 CDS YP_002809786.1 227081235 7772296 1087447..1087983 1 NC_012578.1 AsnC family transcriptional regulator 1087983 7772296 VCM66_1017 Vibrio cholerae M66-2 AsnC family transcriptional regulator YP_002809786.1 1087447 D 579112 CDS YP_002809787.1 227081236 7772297 complement(1087992..1088852) 1 NC_012578.1 acyl-CoA thioesterase II 1088852 tesB 7772297 tesB Vibrio cholerae M66-2 acyl-CoA thioesterase II YP_002809787.1 1087992 R 579112 CDS YP_002809788.1 227081237 7772298 1089003..1089434 1 NC_012578.1 lipoprotein-like protein 1089434 7772298 VCM66_1019 Vibrio cholerae M66-2 lipoprotein-like protein YP_002809788.1 1089003 D 579112 CDS YP_002809789.1 227081238 7772299 complement(1089488..1089790) 1 NC_012578.1 methylated-DNA--protein-cysteine methyltransferase-like protein 1089790 7772299 VCM66_1020 Vibrio cholerae M66-2 methylated-DNA--protein-cysteine methyltransferase-like protein YP_002809789.1 1089488 R 579112 CDS YP_002809790.1 227081239 7772300 1089841..1090584 1 NC_012578.1 hypothetical protein 1090584 7772300 VCM66_1021 Vibrio cholerae M66-2 hypothetical protein YP_002809790.1 1089841 D 579112 CDS YP_002809791.1 227081240 7772301 1090671..1092752 1 NC_012578.1 GGDEF family protein 1092752 7772301 VCM66_1022 Vibrio cholerae M66-2 GGDEF family protein YP_002809791.1 1090671 D 579112 CDS YP_002809792.1 227081241 7772302 1092830..1092991 1 NC_012578.1 hypothetical protein 1092991 7772302 VCM66_1023 Vibrio cholerae M66-2 hypothetical protein YP_002809792.1 1092830 D 579112 CDS YP_002809793.1 227081242 7772303 1093294..1093635 1 NC_012578.1 ArsR family transcriptional regulator 1093635 7772303 VCM66_1024 Vibrio cholerae M66-2 ArsR family transcriptional regulator YP_002809793.1 1093294 D 579112 CDS YP_002809794.1 227081243 7772304 1093732..1094733 1 NC_012578.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1094733 gap 7772304 gap Vibrio cholerae M66-2 glyceraldehyde-3-phosphate dehydrogenase YP_002809794.1 1093732 D 579112 CDS YP_002809795.1 227081244 7772305 1094747..1095244 1 NC_012578.1 putative phosphatase 1095244 7772305 VCM66_1026 Vibrio cholerae M66-2 putative phosphatase YP_002809795.1 1094747 D 579112 CDS YP_002809796.1 227081245 7772306 1095283..1096518 1 NC_012578.1 putative transporter 1096518 7772306 VCM66_1027 Vibrio cholerae M66-2 putative transporter YP_002809796.1 1095283 D 579112 CDS YP_002809797.1 227081246 7772307 1096637..1096780 1 NC_012578.1 hypothetical protein 1096780 7772307 VCM66_1028 Vibrio cholerae M66-2 hypothetical protein YP_002809797.1 1096637 D 579112 CDS YP_002809798.1 227081247 7772308 1097082..1100348 1 NC_012578.1 putative chitinase 1100348 7772308 VCM66_1029 Vibrio cholerae M66-2 putative chitinase YP_002809798.1 1097082 D 579112 CDS YP_002809799.1 227081248 7772309 complement(1100438..1101268) 1 NC_012578.1 hypothetical protein 1101268 7772309 VCM66_1030 Vibrio cholerae M66-2 hypothetical protein YP_002809799.1 1100438 R 579112 CDS YP_002809800.1 227081249 7772310 1101552..1102094 1 NC_012578.1 hypothetical protein 1102094 7772310 VCM66_1031 Vibrio cholerae M66-2 hypothetical protein YP_002809800.1 1101552 D 579112 CDS YP_002809801.1 227081250 7772311 1102107..1102895 1 NC_012578.1 AraC family transcriptional regulator 1102895 7772311 VCM66_1032 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002809801.1 1102107 D 579112 CDS YP_002809802.1 227081251 7772312 complement(1102944..1103432) 1 NC_012578.1 hypothetical protein 1103432 7772312 VCM66_1033 Vibrio cholerae M66-2 hypothetical protein YP_002809802.1 1102944 R 579112 CDS YP_002809803.1 227081252 7772313 complement(1103511..1103651) 1 NC_012578.1 hypothetical protein 1103651 7772313 VCM66_1034 Vibrio cholerae M66-2 hypothetical protein YP_002809803.1 1103511 R 579112 CDS YP_002809804.1 227081253 7772314 complement(1103696..1104685) 1 NC_012578.1 hypothetical protein 1104685 7772314 VCM66_1035 Vibrio cholerae M66-2 hypothetical protein YP_002809804.1 1103696 R 579112 CDS YP_002809805.1 227081254 7772315 1104931..1105296 1 NC_012578.1 Hpt family protein 1105296 7772315 VCM66_1036 Vibrio cholerae M66-2 Hpt family protein YP_002809805.1 1104931 D 579112 CDS YP_002809806.1 227081255 7772316 1105293..1106435 1 NC_012578.1 response regulator 1106435 7772316 VCM66_1037 Vibrio cholerae M66-2 response regulator YP_002809806.1 1105293 D 579112 CDS YP_002809807.1 227081256 7772317 1106470..1106835 1 NC_012578.1 response regulator 1106835 7772317 VCM66_1038 Vibrio cholerae M66-2 response regulator YP_002809807.1 1106470 D 579112 CDS YP_002809808.1 227081257 7772318 1106832..1107416 1 NC_012578.1 hypothetical protein 1107416 7772318 VCM66_1039 Vibrio cholerae M66-2 hypothetical protein YP_002809808.1 1106832 D 579112 CDS YP_002809809.1 227081258 7772319 1107427..1108746 1 NC_012578.1 sensory box sensor histidine kinase 1108746 7772319 VCM66_1040 Vibrio cholerae M66-2 sensory box sensor histidine kinase YP_002809809.1 1107427 D 579112 CDS YP_002809810.1 227081259 7773957 1110063..1111673 1 NC_012578.1 response regulator 1111673 7773957 VCM66_1042 Vibrio cholerae M66-2 response regulator YP_002809810.1 1110063 D 579112 CDS YP_002809811.1 227081260 7772321 1111690..1113033 1 NC_012578.1 response regulator 1113033 7772321 VCM66_1043 Vibrio cholerae M66-2 response regulator YP_002809811.1 1111690 D 579112 CDS YP_002809812.1 227081261 7772322 complement(1113062..1114666) 1 NC_012578.1 sensor histidine kinase 1114666 7772322 VCM66_1044 Vibrio cholerae M66-2 sensor histidine kinase YP_002809812.1 1113062 R 579112 CDS YP_002809813.1 227081262 7772323 complement(1114670..1115482) 1 NC_012578.1 periplasmic binding protein-like protein 1115482 7772323 VCM66_1045 Vibrio cholerae M66-2 periplasmic binding protein-like protein YP_002809813.1 1114670 R 579112 CDS YP_002809814.1 227081263 7772324 complement(1115507..1115650) 1 NC_012578.1 hypothetical protein 1115650 7772324 VCM66_1046 Vibrio cholerae M66-2 hypothetical protein YP_002809814.1 1115507 R 579112 CDS YP_002809815.1 227081264 7772325 1116106..1117737 1 NC_012578.1 oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1117737 oppA 7772325 oppA Vibrio cholerae M66-2 oligopeptide ABC transporter periplasmic oligopeptide-binding protein YP_002809815.1 1116106 D 579112 CDS YP_002809816.1 227081265 7772326 1117886..1118806 1 NC_012578.1 oligopeptide transporter permease 1118806 oppB 7772326 oppB Vibrio cholerae M66-2 oligopeptide transporter permease YP_002809816.1 1117886 D 579112 CDS YP_002809817.1 227081266 7772327 1118820..1119722 1 NC_012578.1 peptide ABC transporter permease 1119722 oppC 7772327 oppC Vibrio cholerae M66-2 peptide ABC transporter permease YP_002809817.1 1118820 D 579112 CDS YP_002809818.1 227081267 7772328 1119747..1120721 1 NC_012578.1 oligopeptide transporter ATP-binding protein 1120721 oppD 7772328 oppD Vibrio cholerae M66-2 oligopeptide transporter ATP-binding protein YP_002809818.1 1119747 D 579112 CDS YP_002809819.1 227081268 7772329 1120700..1121710 1 NC_012578.1 oligopeptide ABC transporter ATP-binding protein 1121710 oppF 7772329 oppF Vibrio cholerae M66-2 oligopeptide ABC transporter ATP-binding protein YP_002809819.1 1120700 D 579112 CDS YP_002809820.1 227081269 7772330 1121860..1122807 1 NC_012578.1 hypothetical protein 1122807 7772330 VCM66_1052 Vibrio cholerae M66-2 hypothetical protein YP_002809820.1 1121860 D 579112 CDS YP_002809821.1 227081270 7772331 complement(1122905..1125049) 1 NC_012578.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1125049 pta 7772331 pta Vibrio cholerae M66-2 phosphate acetyltransferase YP_002809821.1 1122905 R 579112 CDS YP_002809822.1 227081271 7772332 complement(1125185..1126381) 1 NC_012578.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1126381 ackA-1 7772332 ackA-1 Vibrio cholerae M66-2 acetate kinase YP_002809822.1 1125185 R 579112 CDS YP_002809823.1 227081272 7772333 1126728..1127186 1 NC_012578.1 hypothetical protein 1127186 7772333 VCM66_1055 Vibrio cholerae M66-2 hypothetical protein YP_002809823.1 1126728 D 579112 CDS YP_002809824.1 227081273 7772334 complement(1127309..1127719) 1 NC_012578.1 hypothetical protein 1127719 7772334 VCM66_1056 Vibrio cholerae M66-2 hypothetical protein YP_002809824.1 1127309 R 579112 CDS YP_002809825.1 227081274 7772335 1128157..1129122 1 NC_012578.1 hypothetical protein 1129122 7772335 VCM66_1057 Vibrio cholerae M66-2 hypothetical protein YP_002809825.1 1128157 D 579112 CDS YP_002809826.1 227081275 7772336 1129198..1130181 1 NC_012578.1 ABC transporter permease 1130181 7772336 VCM66_1058 Vibrio cholerae M66-2 ABC transporter permease YP_002809826.1 1129198 D 579112 CDS YP_002809827.1 227081276 7772337 1130178..1130972 1 NC_012578.1 ABC transporter ATP-binding protein 1130972 7772337 VCM66_1059 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002809827.1 1130178 D 579112 CDS YP_002809828.1 227081277 7772338 1131139..1132608 1 NC_012578.1 GGDEF family protein 1132608 7772338 VCM66_1060 Vibrio cholerae M66-2 GGDEF family protein YP_002809828.1 1131139 D 579112 CDS YP_002809829.1 227081278 7772339 complement(1132641..1133612) 1 NC_012578.1 hypothetical protein 1133612 7772339 VCM66_1061 Vibrio cholerae M66-2 hypothetical protein YP_002809829.1 1132641 R 579112 CDS YP_002809830.1 227081279 7772340 1133769..1134398 1 NC_012578.1 preprotein translocase SecA subunit-like protein 1134398 7772340 VCM66_1062 Vibrio cholerae M66-2 preprotein translocase SecA subunit-like protein YP_002809830.1 1133769 D 579112 CDS YP_002809831.1 227081280 7772341 1134494..1135090 1 NC_012578.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1135090 lolA 7772341 lolA Vibrio cholerae M66-2 outer-membrane lipoprotein carrier protein YP_002809831.1 1134494 D 579112 CDS YP_002809832.1 227081281 7772342 1135115..1136464 1 NC_012578.1 recombination factor protein RarA 1136464 7772342 VCM66_1064 Vibrio cholerae M66-2 recombination factor protein RarA YP_002809832.1 1135115 D 579112 CDS YP_002809833.1 227081282 7772343 1136464..1136559 1 NC_012578.1 hypothetical protein 1136559 7772343 VCM66_1065 Vibrio cholerae M66-2 hypothetical protein YP_002809833.1 1136464 D 579112 CDS YP_002809834.1 227081283 7772344 1136568..1137875 1 NC_012578.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1137875 serS 7772344 serS Vibrio cholerae M66-2 seryl-tRNA synthetase YP_002809834.1 1136568 D 579112 CDS YP_002809835.1 227081284 7772345 complement(1137982..1139268) 1 NC_012578.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 1139268 bioA 7772345 bioA Vibrio cholerae M66-2 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_002809835.1 1137982 R 579112 CDS YP_002809836.1 227081285 7772346 1139395..1140447 1 NC_012578.1 biotin synthase 1140447 bioB 7772346 bioB Vibrio cholerae M66-2 biotin synthase YP_002809836.1 1139395 D 579112 CDS YP_002809837.1 227081286 7772347 1140431..1141585 1 NC_012578.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1141585 bioF 7772347 bioF Vibrio cholerae M66-2 8-amino-7-oxononanoate synthase YP_002809837.1 1140431 D 579112 CDS YP_002809838.1 227081287 7772348 1141447..1142385 1 NC_012578.1 biotin synthesis protein BioC 1142385 bioC 7772348 bioC Vibrio cholerae M66-2 biotin synthesis protein BioC YP_002809838.1 1141447 D 579112 CDS YP_002809839.1 227081288 7772349 1142361..1143077 1 NC_012578.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1143077 bioD 7772349 bioD Vibrio cholerae M66-2 dithiobiotin synthetase YP_002809839.1 1142361 D 579112 CDS YP_002809840.1 227081289 7772350 complement(1143159..1143368) 1 NC_012578.1 hypothetical protein 1143368 7772350 VCM66_1072 Vibrio cholerae M66-2 hypothetical protein YP_002809840.1 1143159 R 579112 CDS YP_002809841.1 227081290 7772351 1143595..1144458 1 NC_012578.1 putative metalloprotease; heat shock protein HtpX 1144458 htpX 7772351 htpX Vibrio cholerae M66-2 heat shock protein HtpX YP_002809841.1 1143595 D 579112 CDS YP_002809842.1 227081291 7772352 1144668..1145096 1 NC_012578.1 putative transcriptional regulator 1145096 7772352 VCM66_1074 Vibrio cholerae M66-2 putative transcriptional regulator YP_002809842.1 1144668 D 579112 CDS YP_002809843.1 227081292 7772353 1145093..1145818 1 NC_012578.1 short chain dehydrogenase 1145818 7772353 VCM66_1075 Vibrio cholerae M66-2 short chain dehydrogenase YP_002809843.1 1145093 D 579112 CDS YP_002809844.1 227081293 7772354 1145829..1147109 1 NC_012578.1 hypothetical protein 1147109 7772354 VCM66_1076 Vibrio cholerae M66-2 hypothetical protein YP_002809844.1 1145829 D 579112 CDS YP_002809845.1 227081294 7772355 1147109..1147918 1 NC_012578.1 hypothetical protein 1147918 7772355 VCM66_1077 Vibrio cholerae M66-2 hypothetical protein YP_002809845.1 1147109 D 579112 CDS YP_002809846.1 227081295 7772356 1147851..1149149 1 NC_012578.1 cyclopropane-fatty-acyl-phospholipid synthase 1149149 cfa 7772356 cfa Vibrio cholerae M66-2 cyclopropane-fatty-acyl-phospholipid synthase YP_002809846.1 1147851 D 579112 CDS YP_002809847.1 227081296 7772357 1149152..1149691 1 NC_012578.1 hypothetical protein 1149691 7772357 VCM66_1079 Vibrio cholerae M66-2 hypothetical protein YP_002809847.1 1149152 D 579112 CDS YP_002809848.1 227081297 7772358 1149624..1150190 1 NC_012578.1 hypothetical protein 1150190 7772358 VCM66_1080 Vibrio cholerae M66-2 hypothetical protein YP_002809848.1 1149624 D 579112 CDS YP_002809849.1 227081298 7772359 1150187..1150714 1 NC_012578.1 hypothetical protein 1150714 7772359 VCM66_1081 Vibrio cholerae M66-2 hypothetical protein YP_002809849.1 1150187 D 579112 CDS YP_002809850.1 227081299 7772360 complement(1150805..1152175) 1 NC_012578.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1152175 purB 7772360 purB Vibrio cholerae M66-2 adenylosuccinate lyase YP_002809850.1 1150805 R 579112 CDS YP_002809851.1 227081300 7772361 complement(1152233..1152850) 1 NC_012578.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1152850 7772361 VCM66_1083 Vibrio cholerae M66-2 hypothetical protein YP_002809851.1 1152233 R 579112 CDS YP_002809852.1 227081301 7772362 complement(1152873..1153991) 1 NC_012578.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1153991 mnmA 7772362 mnmA Vibrio cholerae M66-2 tRNA-specific 2-thiouridylase MnmA YP_002809852.1 1152873 R 579112 CDS YP_002809853.1 227081302 7772363 1154253..1155557 1 NC_012578.1 inosine-guanosine kinase 1155557 gsk-1 7772363 gsk-1 Vibrio cholerae M66-2 inosine-guanosine kinase YP_002809853.1 1154253 D 579112 CDS YP_002809854.1 227081303 7772364 complement(1155605..1156018) 1 NC_012578.1 DNA-binding protein VicH 1156018 vicH 7772364 vicH Vibrio cholerae M66-2 DNA-binding protein VicH YP_002809854.1 1155605 R 579112 CDS YP_002809855.1 227081304 7772365 1156706..1158307 1 NC_012578.1 hypothetical protein 1158307 7772365 VCM66_1087 Vibrio cholerae M66-2 hypothetical protein YP_002809855.1 1156706 D 579112 CDS YP_002809856.1 227081305 7772366 1158698..1159612 1 NC_012578.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1159612 hisG 7772366 hisG Vibrio cholerae M66-2 ATP phosphoribosyltransferase YP_002809856.1 1158698 D 579112 CDS YP_002809857.1 227081306 7772367 1159617..1160912 1 NC_012578.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1160912 hisD 7772367 hisD Vibrio cholerae M66-2 histidinol dehydrogenase YP_002809857.1 1159617 D 579112 CDS YP_002809858.1 227081307 7772368 1160916..1161956 1 NC_012578.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1161956 hisC 7772368 hisC Vibrio cholerae M66-2 histidinol-phosphate aminotransferase YP_002809858.1 1160916 D 579112 CDS YP_002809859.1 227081308 7772369 1162008..1163081 1 NC_012578.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1163081 hisB 7772369 hisB Vibrio cholerae M66-2 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002809859.1 1162008 D 579112 CDS YP_002809860.1 227081309 7772370 1163081..1163692 1 NC_012578.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1163692 hisH 7772370 hisH Vibrio cholerae M66-2 imidazole glycerol phosphate synthase subunit HisH YP_002809860.1 1163081 D 579112 CDS YP_002809861.1 227081310 7772371 1163735..1164472 1 NC_012578.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1164472 hisA 7772371 hisA Vibrio cholerae M66-2 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002809861.1 1163735 D 579112 CDS YP_002809862.1 227081311 7772372 1164454..1165227 1 NC_012578.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1165227 hisF 7772372 hisF Vibrio cholerae M66-2 imidazole glycerol phosphate synthase subunit HisF YP_002809862.1 1164454 D 579112 CDS YP_002809863.1 227081312 7772373 1165224..1165856 1 NC_012578.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 1165856 hisI 7772373 hisI Vibrio cholerae M66-2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_002809863.1 1165224 D 579112 CDS YP_002809864.1 227081313 7772374 complement(1166057..1166929) 1 NC_012578.1 pseudouridine synthase family 1 protein 1166929 7772374 VCM66_1096 Vibrio cholerae M66-2 pseudouridine synthase family 1 protein YP_002809864.1 1166057 R 579112 CDS YP_002809865.1 227081314 7772375 1167090..1169315 1 NC_012578.1 NADP-dependent isocitrate dehydrogenase 1169315 icd 7772375 icd Vibrio cholerae M66-2 NADP-dependent isocitrate dehydrogenase YP_002809865.1 1167090 D 579112 CDS YP_002809866.1 227081315 7772376 complement(1169414..1169644) 1 NC_012578.1 cold shock-like protein CspD 1169644 cspD 7772376 cspD Vibrio cholerae M66-2 cold shock-like protein CspD YP_002809866.1 1169414 R 579112 CDS YP_002809867.1 227081316 7772377 1170108..1170428 1 NC_012578.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1170428 clpS 7772377 clpS Vibrio cholerae M66-2 ATP-dependent Clp protease adaptor protein ClpS YP_002809867.1 1170108 D 579112 CDS YP_002809868.1 227081317 7772378 1170467..1172737 1 NC_012578.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1172737 clpA 7772378 clpA Vibrio cholerae M66-2 ATP-dependent Clp protease ATP-binding subunit YP_002809868.1 1170467 D 579112 CDS YP_002809869.1 227081318 7772379 complement(1172806..1174482) 1 NC_012578.1 hypothetical protein 1174482 7772379 VCM66_1101 Vibrio cholerae M66-2 hypothetical protein YP_002809869.1 1172806 R 579112 CDS YP_002809870.1 227081319 7772380 complement(1174684..1174962) 1 NC_012578.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 1174962 grxA 7772380 grxA Vibrio cholerae M66-2 glutaredoxin 1 YP_002809870.1 1174684 R 579112 CDS YP_002809871.1 227081320 7772381 1175235..1176503 1 NC_012578.1 iron-containing alcohol dehydrogenase 1176503 7772381 VCM66_1103 Vibrio cholerae M66-2 iron-containing alcohol dehydrogenase YP_002809871.1 1175235 D 579112 CDS YP_002809872.1 227081321 7772382 complement(1176594..1177448) 1 NC_012578.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1177448 7772382 VCM66_1104 Vibrio cholerae M66-2 DNA-binding transcriptional regulator HexR YP_002809872.1 1176594 R 579112 CDS YP_002809873.1 227081322 7772383 complement(1177756..1179402) 1 NC_012578.1 putative glutamate decarboxylase 1179402 7772383 VCM66_1105 Vibrio cholerae M66-2 putative glutamate decarboxylase YP_002809873.1 1177756 R 579112 CDS YP_002809874.1 227081323 7772384 complement(1179512..1180117) 1 NC_012578.1 hypothetical protein 1180117 7772384 VCM66_1106 Vibrio cholerae M66-2 hypothetical protein YP_002809874.1 1179512 R 579112 CDS YP_002809875.1 227081324 7772385 complement(1180210..1181115) 1 NC_012578.1 hypothetical protein 1181115 7772385 VCM66_1107 Vibrio cholerae M66-2 hypothetical protein YP_002809875.1 1180210 R 579112 CDS YP_002809876.1 227081325 7772386 complement(1181136..1182071) 1 NC_012578.1 hypothetical protein 1182071 7772386 VCM66_1108 Vibrio cholerae M66-2 hypothetical protein YP_002809876.1 1181136 R 579112 CDS YP_002809877.1 227081326 7772387 1182413..1183021 1 NC_012578.1 hypothetical protein 1183021 7772387 VCM66_1109 Vibrio cholerae M66-2 hypothetical protein YP_002809877.1 1182413 D 579112 CDS YP_002809878.1 227081327 7772388 complement(1183117..1183665) 1 NC_012578.1 hypothetical protein 1183665 7772388 VCM66_1110 Vibrio cholerae M66-2 hypothetical protein YP_002809878.1 1183117 R 579112 CDS YP_002809879.1 227081328 7772389 complement(1183856..1184401) 1 NC_012578.1 response regulator 1184401 7772389 VCM66_1111 Vibrio cholerae M66-2 response regulator YP_002809879.1 1183856 R 579112 CDS YP_002809880.1 227081329 7772390 complement(1184350..1186305) 1 NC_012578.1 sensor histidine kinase 1186305 7772390 VCM66_1112 Vibrio cholerae M66-2 sensor histidine kinase YP_002809880.1 1184350 R 579112 CDS YP_002809881.1 227081330 7772391 1186528..1187793 1 NC_012578.1 hypothetical protein 1187793 7772391 VCM66_1113 Vibrio cholerae M66-2 hypothetical protein YP_002809881.1 1186528 D 579112 CDS YP_002809882.1 227081331 7772392 1187870..1189009 1 NC_012578.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1189009 serC 7772392 serC Vibrio cholerae M66-2 phosphoserine aminotransferase YP_002809882.1 1187870 D 579112 CDS YP_002809883.1 227081332 7772393 complement(1189090..1190079) 1 NC_012578.1 hypothetical protein 1190079 7772393 VCM66_1115 Vibrio cholerae M66-2 hypothetical protein YP_002809883.1 1189090 R 579112 CDS YP_002809884.1 227081333 7772394 complement(1190079..1191587) 1 NC_012578.1 gonadoliberin III-like protein 1191587 7772394 VCM66_1116 Vibrio cholerae M66-2 gonadoliberin III-like protein YP_002809884.1 1190079 R 579112 CDS YP_002809885.1 227081334 7772395 complement(1191596..1192333) 1 NC_012578.1 Ribosomal protein S6 modification protein 1192333 7772395 VCM66_1117 Vibrio cholerae M66-2 Ribosomal protein S6 modification protein YP_002809885.1 1191596 R 579112 CDS YP_002809886.1 227081335 7772396 complement(1192453..1193424) 1 NC_012578.1 hypothetical protein 1193424 7772396 VCM66_1118 Vibrio cholerae M66-2 hypothetical protein YP_002809886.1 1192453 R 579112 CDS YP_002809887.1 227081336 7772397 complement(1193536..1194276) 1 NC_012578.1 hypothetical protein 1194276 7772397 VCM66_1119 Vibrio cholerae M66-2 hypothetical protein YP_002809887.1 1193536 R 579112 CDS YP_002809888.1 227081337 7772398 complement(1194402..1195271) 1 NC_012578.1 hypothetical protein 1195271 7772398 VCM66_1120 Vibrio cholerae M66-2 hypothetical protein YP_002809888.1 1194402 R 579112 CDS YP_002809889.1 227081338 7772399 1195563..1197338 1 NC_012578.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1197338 aspS 7772399 aspS Vibrio cholerae M66-2 aspartyl-tRNA synthetase YP_002809889.1 1195563 D 579112 CDS YP_002809890.1 227081339 7772400 1197435..1198013 1 NC_012578.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1198013 tdk 7772400 tdk Vibrio cholerae M66-2 thymidine kinase YP_002809890.1 1197435 D 579112 CDS YP_002809891.1 227081340 7772401 complement(1198115..1199491) 1 NC_012578.1 proton/glutamate symporter 1199491 gltP-1 7772401 gltP-1 Vibrio cholerae M66-2 proton/glutamate symporter YP_002809891.1 1198115 R 579112 CDS YP_002809892.1 227081341 7772402 complement(1199687..1200493) 1 NC_012578.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1200493 trpA 7772402 trpA Vibrio cholerae M66-2 tryptophan synthase subunit alpha YP_002809892.1 1199687 R 579112 CDS YP_002809893.1 227081342 7772403 complement(1200493..1201683) 1 NC_012578.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1201683 trpB 7772403 trpB Vibrio cholerae M66-2 tryptophan synthase subunit beta YP_002809893.1 1200493 R 579112 CDS YP_002809894.1 227081343 7772404 complement(1201724..1203133) 1 NC_012578.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1203133 trpC/F 7772404 trpC/F Vibrio cholerae M66-2 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002809894.1 1201724 R 579112 CDS YP_002809895.1 227081344 7772405 complement(1203139..1204200) 1 NC_012578.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1204200 trpD 7772405 trpD Vibrio cholerae M66-2 anthranilate phosphoribosyltransferase YP_002809895.1 1203139 R 579112 CDS YP_002809896.1 227081345 7772406 complement(1204158..1204769) 1 NC_012578.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1204769 trpG 7772406 trpG Vibrio cholerae M66-2 anthranilate synthase component II YP_002809896.1 1204158 R 579112 CDS YP_002809897.1 227081346 7772407 complement(1204766..1206337) 1 NC_012578.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1206337 trpE 7772407 trpE Vibrio cholerae M66-2 anthranilate synthase component I YP_002809897.1 1204766 R 579112 CDS YP_002809898.1 227081347 7772408 complement(1206347..1206439) 1 NC_012578.1 hypothetical protein 1206439 7772408 VCM66_1130 Vibrio cholerae M66-2 hypothetical protein YP_002809898.1 1206347 R 579112 CDS YP_002809899.1 227081348 7772409 complement(1206471..1206608) 1 NC_012578.1 hypothetical protein 1206608 7772409 VCM66_1131 Vibrio cholerae M66-2 hypothetical protein YP_002809899.1 1206471 R 579112 CDS YP_002809900.1 227081349 7772410 1206673..1207545 1 NC_012578.1 hypothetical protein 1207545 7772410 VCM66_1132 Vibrio cholerae M66-2 hypothetical protein YP_002809900.1 1206673 D 579112 CDS YP_002809901.1 227081350 7772411 1207548..1208168 1 NC_012578.1 hypothetical protein 1208168 7772411 VCM66_1133 Vibrio cholerae M66-2 hypothetical protein YP_002809901.1 1207548 D 579112 CDS YP_002809902.1 227081351 7772412 1208301..1209266 1 NC_012578.1 pseudouridine synthase family 1 protein 1209266 7772412 VCM66_1134 Vibrio cholerae M66-2 pseudouridine synthase family 1 protein YP_002809902.1 1208301 D 579112 CDS YP_002809903.1 227081352 7772413 complement(1209434..1211155) 1 NC_012578.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1211155 cydC 7772413 cydC Vibrio cholerae M66-2 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002809903.1 1209434 R 579112 CDS YP_002809904.1 227081353 7772414 complement(1211148..1212935) 1 NC_012578.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1212935 cydD 7772414 cydD Vibrio cholerae M66-2 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002809904.1 1211148 R 579112 CDS YP_002809905.1 227081354 7772415 complement(1213055..1214011) 1 NC_012578.1 thioredoxin reductase 1214011 trxB 7772415 trxB Vibrio cholerae M66-2 thioredoxin reductase YP_002809905.1 1213055 R 579112 CDS YP_002809906.1 227081355 7772416 1214486..1215145 1 NC_012578.1 hypothetical protein 1215145 7772416 VCM66_1138 Vibrio cholerae M66-2 hypothetical protein YP_002809906.1 1214486 D 579112 CDS YP_002809907.1 227081356 7772417 1215120..1216370 1 NC_012578.1 NifS-like protein 1216370 7772417 VCM66_1139 Vibrio cholerae M66-2 NifS-like protein YP_002809907.1 1215120 D 579112 CDS YP_002809908.1 227081357 7772418 1216628..1217959 1 NC_012578.1 GGDEF family protein 1217959 7772418 VCM66_1140 Vibrio cholerae M66-2 GGDEF family protein YP_002809908.1 1216628 D 579112 CDS YP_002809909.1 227081358 7772419 complement(1218060..1218824) 1 NC_012578.1 sanA protein 1218824 sanA 7772419 sanA Vibrio cholerae M66-2 sanA protein YP_002809909.1 1218060 R 579112 CDS YP_002809910.1 227081359 7772420 complement(1218797..1219165) 1 NC_012578.1 hypothetical protein 1219165 7772420 VCM66_1142 Vibrio cholerae M66-2 hypothetical protein YP_002809910.1 1218797 R 579112 CDS YP_002809911.1 227081360 7772421 complement(1219169..1220935) 1 NC_012578.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1220935 sfcA 7772421 sfcA Vibrio cholerae M66-2 malate dehydrogenase YP_002809911.1 1219169 R 579112 CDS YP_002809912.1 227081361 7772422 1221251..1221673 1 NC_012578.1 hypothetical protein 1221673 7772422 VCM66_1144 Vibrio cholerae M66-2 hypothetical protein YP_002809912.1 1221251 D 579112 CDS YP_002809913.1 227081362 7772423 complement(1221875..1223092) 1 NC_012578.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1223092 7772423 VCM66_1145 Vibrio cholerae M66-2 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002809913.1 1221875 R 579112 CDS YP_002809914.1 227081363 7772424 complement(1223147..1223545) 1 NC_012578.1 hypothetical protein 1223545 7772424 VCM66_1146 Vibrio cholerae M66-2 hypothetical protein YP_002809914.1 1223147 R 579112 CDS YP_002809915.1 227081364 7772425 1223592..1223699 1 NC_012578.1 hypothetical protein 1223699 7772425 VCM66_1147 Vibrio cholerae M66-2 hypothetical protein YP_002809915.1 1223592 D 579112 CDS YP_002809916.1 227081365 7772426 complement(1223837..1224034) 1 NC_012578.1 hypothetical protein 1224034 7772426 VCM66_1148 Vibrio cholerae M66-2 hypothetical protein YP_002809916.1 1223837 R 579112 CDS YP_002809917.1 227081366 7772427 complement(1224170..1225222) 1 NC_012578.1 hypothetical protein 1225222 7772427 VCM66_1149 Vibrio cholerae M66-2 hypothetical protein YP_002809917.1 1224170 R 579112 CDS YP_002809918.1 227081367 7772428 complement(1225287..1225958) 1 NC_012578.1 putative lipoprotein 1225958 7772428 VCM66_1150 Vibrio cholerae M66-2 putative lipoprotein YP_002809918.1 1225287 R 579112 CDS YP_002809919.1 227081368 7772429 complement(1226058..1226747) 1 NC_012578.1 hypothetical protein 1226747 7772429 VCM66_1151 Vibrio cholerae M66-2 hypothetical protein YP_002809919.1 1226058 R 579112 CDS YP_002809920.1 227081369 7772430 complement(1226872..1227567) 1 NC_012578.1 hypothetical protein 1227567 7772430 VCM66_1152 Vibrio cholerae M66-2 hypothetical protein YP_002809920.1 1226872 R 579112 CDS YP_002809921.1 227081370 7772431 1227738..1230803 1 NC_012578.1 hypothetical protein 1230803 7772431 VCM66_1153 Vibrio cholerae M66-2 hypothetical protein YP_002809921.1 1227738 D 579112 CDS YP_002809922.1 227081371 7772432 1230853..1231320 1 NC_012578.1 hypothetical protein 1231320 7772432 VCM66_1154 Vibrio cholerae M66-2 hypothetical protein YP_002809922.1 1230853 D 579112 CDS YP_002809923.1 227081372 7772433 1231570..1232781 1 NC_012578.1 putative trypsin 1232781 7772433 VCM66_1155 Vibrio cholerae M66-2 putative trypsin YP_002809923.1 1231570 D 579112 CDS YP_002809924.1 227081373 7772434 complement(1232856..1233581) 1 NC_012578.1 hypothetical protein 1233581 7772434 VCM66_1156 Vibrio cholerae M66-2 hypothetical protein YP_002809924.1 1232856 R 579112 CDS YP_002809925.1 227081374 7772435 complement(1233730..1235265) 1 NC_012578.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 1235265 hutH 7772435 hutH Vibrio cholerae M66-2 histidine ammonia-lyase YP_002809925.1 1233730 R 579112 CDS YP_002809926.1 227081375 7772436 complement(1235277..1236974) 1 NC_012578.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1236974 hutU 7772436 hutU Vibrio cholerae M66-2 urocanate hydratase YP_002809926.1 1235277 R 579112 CDS YP_002809927.1 227081376 7772437 complement(1236993..1238003) 1 NC_012578.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 1238003 hutG 7772437 hutG Vibrio cholerae M66-2 formimidoylglutamase YP_002809927.1 1236993 R 579112 CDS YP_002809928.1 227081377 7772438 complement(1237993..1239201) 1 NC_012578.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 1239201 hutI 7772438 hutI Vibrio cholerae M66-2 imidazolonepropionase YP_002809928.1 1237993 R 579112 CDS YP_002809929.1 227081378 7772439 complement(1239305..1240015) 1 NC_012578.1 histidine utilization repressor 1240015 7772439 VCM66_1161 Vibrio cholerae M66-2 histidine utilization repressor YP_002809929.1 1239305 R 579112 CDS YP_002809930.1 227081379 7772440 complement(1240132..1241079) 1 NC_012578.1 hypothetical protein 1241079 7772440 VCM66_1162 Vibrio cholerae M66-2 hypothetical protein YP_002809930.1 1240132 R 579112 CDS YP_002809931.1 227081380 7772441 complement(1241218..1241538) 1 NC_012578.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1241538 7772441 VCM66_1163 Vibrio cholerae M66-2 dsDNA-mimic protein YP_002809931.1 1241218 R 579112 CDS YP_002809932.1 227081381 7772442 complement(1241543..1242142) 1 NC_012578.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 1242142 7772442 VCM66_1164 Vibrio cholerae M66-2 elongation factor P YP_002809932.1 1241543 R 579112 CDS YP_002809933.1 227081382 7772443 1242301..1243095 1 NC_012578.1 hypothetical protein 1243095 7772443 VCM66_1165 Vibrio cholerae M66-2 hypothetical protein YP_002809933.1 1242301 D 579112 CDS YP_002809934.1 227081383 7772444 1243189..1245303 1 NC_012578.1 EAL family protein 1245303 7772444 VCM66_1166 Vibrio cholerae M66-2 EAL family protein YP_002809934.1 1243189 D 579112 CDS YP_002809935.1 227081384 7772445 complement(1245275..1247638) 1 NC_012578.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 1247638 polB 7772445 polB Vibrio cholerae M66-2 DNA polymerase II YP_002809935.1 1245275 R 579112 CDS YP_002809936.1 227081385 7772446 1248014..1248658 1 NC_012578.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1248658 7772446 VCM66_1168 Vibrio cholerae M66-2 response regulator YP_002809936.1 1248014 D 579112 CDS YP_002809937.1 227081386 7772447 1248658..1250490 1 NC_012578.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1250490 uvrC 7772447 uvrC Vibrio cholerae M66-2 excinuclease ABC subunit C YP_002809937.1 1248658 D 579112 CDS YP_002809938.1 227081387 7772448 1250538..1251095 1 NC_012578.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1251095 pgsA 7772448 pgsA Vibrio cholerae M66-2 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002809938.1 1250538 D 579112 CDS YP_002809939.1 227081388 7774027 1251988..1253106 1 NC_012578.1 GGDEF family protein 1253106 7774027 VCM66_1171 Vibrio cholerae M66-2 GGDEF family protein YP_002809939.1 1251988 D 579112 CDS YP_002809940.1 227081389 7772450 complement(1253103..1253588) 1 NC_012578.1 hypothetical protein 1253588 7772450 VCM66_1172 Vibrio cholerae M66-2 hypothetical protein YP_002809940.1 1253103 R 579112 CDS YP_002809941.1 227081390 7772451 1253731..1253847 1 NC_012578.1 hypothetical protein 1253847 7772451 VCM66_1173 Vibrio cholerae M66-2 hypothetical protein YP_002809941.1 1253731 D 579112 CDS YP_002809942.1 227081391 7772452 1253879..1254862 1 NC_012578.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1254862 pheS 7772452 pheS Vibrio cholerae M66-2 phenylalanyl-tRNA synthetase subunit alpha YP_002809942.1 1253879 D 579112 CDS YP_002809943.1 227081392 7772453 1254889..1257276 1 NC_012578.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1257276 pheT 7772453 pheT Vibrio cholerae M66-2 phenylalanyl-tRNA synthetase subunit beta YP_002809943.1 1254889 D 579112 CDS YP_002809944.1 227081393 7772454 1257559..1257693 1 NC_012578.1 hypothetical protein 1257693 7772454 VCM66_1176 Vibrio cholerae M66-2 hypothetical protein YP_002809944.1 1257559 D 579112 CDS YP_002809945.1 227081394 7772455 1257715..1258011 1 NC_012578.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1258011 ihfA 7772455 ihfA Vibrio cholerae M66-2 integration host factor subunit alpha YP_002809945.1 1257715 D 579112 CDS YP_002809946.1 227081395 7772456 complement(1257995..1258231) 1 NC_012578.1 hypothetical protein 1258231 7772456 VCM66_1178 Vibrio cholerae M66-2 hypothetical protein YP_002809946.1 1257995 R 579112 CDS YP_002809947.1 227081396 7772457 complement(1258140..1258919) 1 NC_012578.1 hypothetical protein 1258919 7772457 VCM66_1179 Vibrio cholerae M66-2 hypothetical protein YP_002809947.1 1258140 R 579112 CDS YP_002809948.1 227081397 7772458 1258991..1259236 1 NC_012578.1 hypothetical protein 1259236 7772458 VCM66_1180 Vibrio cholerae M66-2 hypothetical protein YP_002809948.1 1258991 D 579112 CDS YP_002809949.1 227081398 7772459 1259388..1260044 1 NC_012578.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase 1260044 7772459 VCM66_1181 Vibrio cholerae M66-2 thiopurine S-methyltransferase YP_002809949.1 1259388 D 579112 CDS YP_002809950.1 227081399 7772460 complement(1259997..1260167) 1 NC_012578.1 hypothetical protein 1260167 7772460 VCM66_1182 Vibrio cholerae M66-2 hypothetical protein YP_002809950.1 1259997 R 579112 CDS YP_002809951.1 227081400 7772461 complement(1260137..1261318) 1 NC_012578.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1261318 purT 7772461 purT Vibrio cholerae M66-2 phosphoribosylglycinamide formyltransferase 2 YP_002809951.1 1260137 R 579112 CDS YP_002809952.1 227081401 7772462 complement(1261466..1262341) 1 NC_012578.1 hypothetical protein 1262341 7772462 VCM66_1184 Vibrio cholerae M66-2 hypothetical protein YP_002809952.1 1261466 R 579112 CDS YP_002809953.1 227081402 7772463 1262418..1262537 1 NC_012578.1 hypothetical protein 1262537 7772463 VCM66_1185 Vibrio cholerae M66-2 hypothetical protein YP_002809953.1 1262418 D 579112 CDS YP_002809954.1 227081403 7772464 complement(1262500..1263387) 1 NC_012578.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1263387 cdd 7772464 cdd Vibrio cholerae M66-2 cytidine deaminase YP_002809954.1 1262500 R 579112 CDS YP_002809955.1 227081404 7772465 complement(1263557..1264231) 1 NC_012578.1 putative Inner membrane protein 1264231 7772465 VCM66_1187 Vibrio cholerae M66-2 putative Inner membrane protein YP_002809955.1 1263557 R 579112 CDS YP_002809956.1 227081405 7772466 complement(1264222..1264611) 1 NC_012578.1 hypothetical protein 1264611 7772466 VCM66_1188 Vibrio cholerae M66-2 hypothetical protein YP_002809956.1 1264222 R 579112 CDS YP_002809957.1 227081406 7772467 complement(1264628..1266052) 1 NC_012578.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1266052 sbcB 7772467 sbcB Vibrio cholerae M66-2 exonuclease I YP_002809957.1 1264628 R 579112 CDS YP_002809958.1 227081407 7772468 complement(1266198..1267613) 1 NC_012578.1 sodium/dicarboxylate symporter 1267613 7772468 VCM66_1190 Vibrio cholerae M66-2 sodium/dicarboxylate symporter YP_002809958.1 1266198 R 579112 CDS YP_002809959.1 227081408 7772469 1267917..1268363 1 NC_012578.1 PilB-like protein 1268363 7772469 VCM66_1191 Vibrio cholerae M66-2 PilB-like protein YP_002809959.1 1267917 D 579112 CDS YP_002809960.1 227081409 7772470 1268890..1269999 1 NC_012578.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1269999 cobT 7772470 cobT Vibrio cholerae M66-2 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_002809960.1 1268890 D 579112 CDS YP_002809961.1 227081410 7772471 1269999..1270784 1 NC_012578.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1270784 cobS 7772471 cobS Vibrio cholerae M66-2 cobalamin synthase YP_002809961.1 1269999 D 579112 CDS YP_002809962.1 227081411 7772472 1270793..1271332 1 NC_012578.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1271332 cobU 7772472 cobU Vibrio cholerae M66-2 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_002809962.1 1270793 D 579112 CDS YP_002809963.1 227081412 7772473 1271339..1271941 1 NC_012578.1 putative alpha-ribazole-5`-phosphate phosphatase CobC 1271941 7772473 VCM66_1195 Vibrio cholerae M66-2 putative alpha-ribazole-5`-phosphate phosphatase CobC YP_002809963.1 1271339 D 579112 CDS YP_002809964.1 227081413 7772474 1272099..1272206 1 NC_012578.1 hypothetical protein 1272206 7772474 VCM66_1196 Vibrio cholerae M66-2 hypothetical protein YP_002809964.1 1272099 D 579112 CDS YP_002809965.1 227081414 7772475 1272257..1273285 1 NC_012578.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1273285 astE 7772475 astE Vibrio cholerae M66-2 succinylglutamate desuccinylase YP_002809965.1 1272257 D 579112 CDS YP_002809966.1 227081415 7772476 complement(1273255..1273401) 1 NC_012578.1 hypothetical protein 1273401 7772476 VCM66_1198 Vibrio cholerae M66-2 hypothetical protein YP_002809966.1 1273255 R 579112 CDS YP_002809967.1 227081416 7772477 1273354..1274361 1 NC_012578.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1274361 7772477 VCM66_1199 Vibrio cholerae M66-2 vtamin B12-transporter permease YP_002809967.1 1273354 D 579112 CDS YP_002809968.1 227081417 7772478 1274348..1275103 1 NC_012578.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1275103 7772478 VCM66_1200 Vibrio cholerae M66-2 vitamin B12-transporter ATPase YP_002809968.1 1274348 D 579112 CDS YP_002809969.1 227081418 7772479 complement(1275488..1276063) 1 NC_012578.1 hypothetical protein 1276063 7772479 VCM66_1201 Vibrio cholerae M66-2 hypothetical protein YP_002809969.1 1275488 R 579112 CDS YP_002809970.1 227081419 7772480 complement(1276242..1276637) 1 NC_012578.1 hypothetical protein 1276637 7772480 VCM66_1202 Vibrio cholerae M66-2 hypothetical protein YP_002809970.1 1276242 R 579112 CDS YP_002809971.1 227081420 7772481 complement(1276685..1278295) 1 NC_012578.1 methyl-accepting chemotaxis protein 1278295 7772481 VCM66_1203 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002809971.1 1276685 R 579112 CDS YP_002809972.1 227081421 7772482 complement(1278526..1279038) 1 NC_012578.1 hypothetical protein 1279038 7772482 VCM66_1204 Vibrio cholerae M66-2 hypothetical protein YP_002809972.1 1278526 R 579112 CDS YP_002809973.1 227081422 7772483 complement(1279304..1280203) 1 NC_012578.1 hypothetical protein 1280203 7772483 VCM66_1205 Vibrio cholerae M66-2 hypothetical protein YP_002809973.1 1279304 R 579112 CDS YP_002809974.1 227081423 7772484 complement(1280216..1280314) 1 NC_012578.1 hypothetical protein 1280314 7772484 VCM66_1206 Vibrio cholerae M66-2 hypothetical protein YP_002809974.1 1280216 R 579112 CDS YP_002809975.1 227081424 7772485 1280367..1281614 1 NC_012578.1 putative competence damage protein CinA 1281614 7772485 VCM66_1207 Vibrio cholerae M66-2 putative competence damage protein CinA YP_002809975.1 1280367 D 579112 CDS YP_002809976.1 227081425 7772486 complement(1281787..1282215) 1 NC_012578.1 hypothetical protein 1282215 7772486 VCM66_1208 Vibrio cholerae M66-2 hypothetical protein YP_002809976.1 1281787 R 579112 CDS YP_002809977.1 227081426 7772487 complement(1282316..1282594) 1 NC_012578.1 putative iron-sulfur cluster-binding protein 1282594 7772487 VCM66_1209 Vibrio cholerae M66-2 putative iron-sulfur cluster-binding protein YP_002809977.1 1282316 R 579112 CDS YP_002809978.1 227081427 7772488 complement(1282594..1283763) 1 NC_012578.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1283763 nrdB 7772488 nrdB Vibrio cholerae M66-2 ribonucleotide-diphosphate reductase subunit beta YP_002809978.1 1282594 R 579112 CDS YP_002809979.1 227081428 7772489 complement(1283823..1286108) 1 NC_012578.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1286108 nrdA 7772489 nrdA Vibrio cholerae M66-2 ribonucleotide-diphosphate reductase subunit alpha YP_002809979.1 1283823 R 579112 CDS YP_002809980.1 227081429 7772490 complement(1286557..1287294) 1 NC_012578.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1287294 ubiG 7772490 ubiG Vibrio cholerae M66-2 3-demethylubiquinone-9 3-methyltransferase YP_002809980.1 1286557 R 579112 CDS YP_002809981.1 227081430 7772491 1287646..1290330 1 NC_012578.1 DNA gyrase subunit A 1290330 gyrA 7772491 gyrA Vibrio cholerae M66-2 DNA gyrase subunit A YP_002809981.1 1287646 D 579112 CDS YP_002809982.1 227081431 7772492 1290543..1291541 1 NC_012578.1 hypothetical protein 1291541 7772492 VCM66_1214 Vibrio cholerae M66-2 hypothetical protein YP_002809982.1 1290543 D 579112 CDS YP_002809983.1 227081432 7772493 complement(1291568..1292467) 1 NC_012578.1 AraC family transcriptional regulator 1292467 7772493 VCM66_1215 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002809983.1 1291568 R 579112 CDS YP_002809984.1 227081433 7772494 1292718..1293932 1 NC_012578.1 Sugar efflux transporter A 1293932 7772494 VCM66_1216 Vibrio cholerae M66-2 Sugar efflux transporter A YP_002809984.1 1292718 D 579112 CDS YP_002809985.1 227081434 7772495 1294115..1294291 1 NC_012578.1 hypothetical protein 1294291 7772495 VCM66_1217 Vibrio cholerae M66-2 hypothetical protein YP_002809985.1 1294115 D 579112 CDS YP_002809986.1 227081435 7772496 1294462..1295112 1 NC_012578.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1295112 ribA 7772496 ribA Vibrio cholerae M66-2 GTP cyclohydrolase II YP_002809986.1 1294462 D 579112 CDS YP_002809987.1 227081436 7772497 1295247..1296554 1 NC_012578.1 putative iron-regulated protein A 1296554 7772497 VCM66_1219 Vibrio cholerae M66-2 putative iron-regulated protein A YP_002809987.1 1295247 D 579112 CDS YP_002809988.1 227081437 7772498 1296761..1298146 1 NC_012578.1 hypothetical protein 1298146 7772498 VCM66_1220 Vibrio cholerae M66-2 hypothetical protein YP_002809988.1 1296761 D 579112 CDS YP_002809989.1 227081438 7772499 1298156..1299163 1 NC_012578.1 hypothetical protein 1299163 7772499 VCM66_1221 Vibrio cholerae M66-2 hypothetical protein YP_002809989.1 1298156 D 579112 CDS YP_002809990.1 227081439 7772500 1299144..1300226 1 NC_012578.1 hypothetical protein 1300226 7772500 VCM66_1222 Vibrio cholerae M66-2 hypothetical protein YP_002809990.1 1299144 D 579112 CDS YP_002809991.1 227081440 7772501 1300473..1302047 1 NC_012578.1 hypothetical protein 1302047 7772501 VCM66_1223 Vibrio cholerae M66-2 hypothetical protein YP_002809991.1 1300473 D 579112 CDS YP_002809992.1 227081441 7772502 1302193..1302741 1 NC_012578.1 putative lipoprotein 1302741 7772502 VCM66_1224 Vibrio cholerae M66-2 putative lipoprotein YP_002809992.1 1302193 D 579112 CDS YP_002809993.1 227081442 7772503 1302805..1303461 1 NC_012578.1 glyoxylase II family protein 1303461 7772503 VCM66_1225 Vibrio cholerae M66-2 glyoxylase II family protein YP_002809993.1 1302805 D 579112 CDS YP_002809994.1 227081443 7772504 complement(1303455..1304171) 1 NC_012578.1 hypothetical protein 1304171 7772504 VCM66_1226 Vibrio cholerae M66-2 hypothetical protein YP_002809994.1 1303455 R 579112 CDS YP_002809995.1 227081444 7772505 1304275..1304700 1 NC_012578.1 hypothetical protein 1304700 7772505 VCM66_1227 Vibrio cholerae M66-2 hypothetical protein YP_002809995.1 1304275 D 579112 CDS YP_002809996.1 227081445 7772506 1304975..1306180 1 NC_012578.1 putative extracellular solute-binding protein 1306180 7772506 VCM66_1228 Vibrio cholerae M66-2 putative extracellular solute-binding protein YP_002809996.1 1304975 D 579112 CDS YP_002809997.1 227081446 7772507 1306282..1306815 1 NC_012578.1 hypothetical protein 1306815 7772507 VCM66_1229 Vibrio cholerae M66-2 hypothetical protein YP_002809997.1 1306282 D 579112 CDS YP_002809998.1 227081447 7772508 1306825..1308108 1 NC_012578.1 Putative TRAP transporter large permease 1308108 7772508 VCM66_1230 Vibrio cholerae M66-2 Putative TRAP transporter large permease YP_002809998.1 1306825 D 579112 CDS YP_002809999.1 227081448 7772509 1308215..1309570 1 NC_012578.1 sensor histidine kinase 1309570 7772509 VCM66_1231 Vibrio cholerae M66-2 sensor histidine kinase YP_002809999.1 1308215 D 579112 CDS YP_002810000.1 227081449 7772510 1309551..1310201 1 NC_012578.1 LuxR family transcriptional regulator 1310201 7772510 VCM66_1232 Vibrio cholerae M66-2 LuxR family transcriptional regulator YP_002810000.1 1309551 D 579112 CDS YP_002810001.1 227081450 7772511 complement(1310203..1310682) 1 NC_012578.1 MarR family transcriptional regulator 1310682 7772511 VCM66_1233 Vibrio cholerae M66-2 MarR family transcriptional regulator YP_002810001.1 1310203 R 579112 CDS YP_002810002.1 227081451 7772512 1311039..1312661 1 NC_012578.1 transporter, BCCT family 1312661 7772512 VCM66_1234 Vibrio cholerae M66-2 transporter, BCCT family YP_002810002.1 1311039 D 579112 CDS YP_002810003.1 227081452 7772513 complement(1312826..1314121) 1 NC_012578.1 hypothetical protein 1314121 7772513 VCM66_1235 Vibrio cholerae M66-2 hypothetical protein YP_002810003.1 1312826 R 579112 CDS YP_002810004.1 227081453 7772514 1314364..1314669 1 NC_012578.1 PTS system cellobiose-specific transporter subunit IIB 1314669 celA 7772514 celA Vibrio cholerae M66-2 PTS system cellobiose-specific transporter subunit IIB YP_002810004.1 1314364 D 579112 CDS YP_002810005.1 227081454 7772515 1314748..1316088 1 NC_012578.1 PTS system cellobiose-specific transporter subunit IIC 1316088 celB 7772515 celB Vibrio cholerae M66-2 PTS system cellobiose-specific transporter subunit IIC YP_002810005.1 1314748 D 579112 CDS YP_002810006.1 227081455 7772516 1316135..1316470 1 NC_012578.1 PTS system cellobiose-specific transporter subunit IIA 1316470 celC 7772516 celC Vibrio cholerae M66-2 PTS system cellobiose-specific transporter subunit IIA YP_002810006.1 1316135 D 579112 CDS YP_002810007.1 227081456 7772517 1316452..1317774 1 NC_012578.1 6-phospho-beta-glucosidase 1317774 celF 7772517 celF Vibrio cholerae M66-2 6-phospho-beta-glucosidase YP_002810007.1 1316452 D 579112 CDS YP_002810008.1 227081457 7772518 1317797..1318555 1 NC_012578.1 hypothetical protein 1318555 7772518 VCM66_1240 Vibrio cholerae M66-2 hypothetical protein YP_002810008.1 1317797 D 579112 CDS YP_002810009.1 227081458 7772519 1318656..1319678 1 NC_012578.1 LacI family transcriptional regulator 1319678 7772519 VCM66_1241 Vibrio cholerae M66-2 LacI family transcriptional regulator YP_002810009.1 1318656 D 579112 CDS YP_002810010.1 227081459 7773958 complement(1322009..1323646) 1 NC_012578.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1323646 mdoG 7773958 mdoG Vibrio cholerae M66-2 glucan biosynthesis protein G YP_002810010.1 1322009 R 579112 CDS YP_002810011.1 227081460 7772521 1324039..1325934 1 NC_012578.1 methyl-accepting chemotaxis protein 1325934 7772521 VCM66_1244 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810011.1 1324039 D 579112 CDS YP_002810012.1 227081461 7772522 complement(1326073..1326783) 1 NC_012578.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1326783 7772522 VCM66_1245 Vibrio cholerae M66-2 DNA polymerase III subunit epsilon YP_002810012.1 1326073 R 579112 CDS YP_002810013.1 227081462 7772523 complement(1326780..1328504) 1 NC_012578.1 hypothetical protein 1328504 7772523 VCM66_1246 Vibrio cholerae M66-2 hypothetical protein YP_002810013.1 1326780 R 579112 CDS YP_002810014.1 227081463 7772524 1328907..1329008 1 NC_012578.1 hypothetical protein 1329008 7772524 VCM66_1247 Vibrio cholerae M66-2 hypothetical protein YP_002810014.1 1328907 D 579112 CDS YP_002810015.1 227081464 7772525 complement(1328973..1330214) 1 NC_012578.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1330214 aspC 7772525 aspC Vibrio cholerae M66-2 aromatic amino acid aminotransferase YP_002810015.1 1328973 R 579112 CDS YP_002810016.1 227081465 7772526 complement(1330375..1330560) 1 NC_012578.1 hypothetical protein 1330560 7772526 VCM66_1249 Vibrio cholerae M66-2 hypothetical protein YP_002810016.1 1330375 R 579112 CDS YP_002810017.1 227081466 7772527 complement(1330532..1332010) 1 NC_012578.1 hypothetical protein 1332010 7772527 VCM66_1250 Vibrio cholerae M66-2 hypothetical protein YP_002810017.1 1330532 R 579112 CDS YP_002810018.1 227081467 7772528 1332519..1333367 1 NC_012578.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1333367 thiD 7772528 thiD Vibrio cholerae M66-2 phosphomethylpyrimidine kinase YP_002810018.1 1332519 D 579112 CDS YP_002810019.1 227081468 7772529 complement(1333433..1334878) 1 NC_012578.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1334878 asnC 7772529 asnC Vibrio cholerae M66-2 asparaginyl-tRNA synthetase YP_002810019.1 1333433 R 579112 CDS YP_002810020.1 227081469 7772530 complement(1334980..1336611) 1 NC_012578.1 methyl-accepting chemotaxis protein 1336611 7772530 VCM66_1253 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810020.1 1334980 R 579112 CDS YP_002810021.1 227081470 7772531 1337009..1337377 1 NC_012578.1 6-pyruvoyl tetrahydrobiopterin synthase 1337377 7772531 VCM66_1254 Vibrio cholerae M66-2 6-pyruvoyl tetrahydrobiopterin synthase YP_002810021.1 1337009 D 579112 CDS YP_002810022.1 227081471 7772532 complement(1337466..1338827) 1 NC_012578.1 L-serine dehydratase 1338827 sdaA-1 7772532 sdaA-1 Vibrio cholerae M66-2 L-serine dehydratase YP_002810022.1 1337466 R 579112 CDS YP_002810023.1 227081472 7772533 complement(1338920..1340173) 1 NC_012578.1 serine transporter 1340173 sdaC-1 7772533 sdaC-1 Vibrio cholerae M66-2 serine transporter YP_002810023.1 1338920 R 579112 CDS YP_002810024.1 227081473 7772534 complement(1340472..1341086) 1 NC_012578.1 MutT/nudix family protein 1341086 7772534 VCM66_1257 Vibrio cholerae M66-2 MutT/nudix family protein YP_002810024.1 1340472 R 579112 CDS YP_002810025.1 227081474 7772535 complement(1341283..1342659) 1 NC_012578.1 para-aminobenzoate synthase, component I 1342659 pabB 7772535 pabB Vibrio cholerae M66-2 para-aminobenzoate synthase, component I YP_002810025.1 1341283 R 579112 CDS YP_002810026.1 227081475 7772536 1342835..1344352 1 NC_012578.1 putative fumarate hydratase, class I 1344352 7772536 VCM66_1259 Vibrio cholerae M66-2 putative fumarate hydratase, class I YP_002810026.1 1342835 D 579112 CDS YP_002810027.1 227081476 7772537 1344501..1344686 1 NC_012578.1 hypothetical protein 1344686 7772537 VCM66_1260 Vibrio cholerae M66-2 hypothetical protein YP_002810027.1 1344501 D 579112 CDS YP_002810028.1 227081477 7772538 1344911..1346284 1 NC_012578.1 hypothetical protein 1346284 7772538 VCM66_1261 Vibrio cholerae M66-2 hypothetical protein YP_002810028.1 1344911 D 579112 CDS YP_002810029.1 227081478 7772539 1346281..1347300 1 NC_012578.1 hypothetical protein 1347300 7772539 VCM66_1262 Vibrio cholerae M66-2 hypothetical protein YP_002810029.1 1346281 D 579112 CDS YP_002810030.1 227081479 7772540 1347414..1348955 1 NC_012578.1 transcriptional regulator TyrR 1348955 tyrR 7772540 tyrR Vibrio cholerae M66-2 transcriptional regulator TyrR YP_002810030.1 1347414 D 579112 CDS YP_002810031.1 227081480 7772541 1348955..1349530 1 NC_012578.1 ribosomal-protein-alanine acetyltransferase 1349530 rimJ 7772541 rimJ Vibrio cholerae M66-2 ribosomal-protein-alanine acetyltransferase YP_002810031.1 1348955 D 579112 CDS YP_002810032.1 227081481 7772542 1349625..1350098 1 NC_012578.1 hypothetical protein 1350098 7772542 VCM66_1265 Vibrio cholerae M66-2 hypothetical protein YP_002810032.1 1349625 D 579112 CDS YP_002810033.1 227081482 7772543 complement(1350166..1351044) 1 NC_012578.1 putative Inner membrane protein 1351044 7772543 VCM66_1266 Vibrio cholerae M66-2 putative Inner membrane protein YP_002810033.1 1350166 R 579112 CDS YP_002810034.1 227081483 7772544 complement(1351165..1352451) 1 NC_012578.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1352451 7772544 VCM66_1267 Vibrio cholerae M66-2 alanine racemase YP_002810034.1 1351165 R 579112 CDS YP_002810035.1 227081484 7772545 complement(1352500..1354131) 1 NC_012578.1 methyl-accepting chemotaxis protein 1354131 7772545 VCM66_1268 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810035.1 1352500 R 579112 CDS YP_002810036.1 227081485 7772546 1354465..1355928 1 NC_012578.1 putative transporter 1355928 7772546 VCM66_1269 Vibrio cholerae M66-2 putative transporter YP_002810036.1 1354465 D 579112 CDS YP_002810037.1 227081486 7772547 1355938..1357287 1 NC_012578.1 sensor histidine kinase 1357287 7772547 VCM66_1270 Vibrio cholerae M66-2 sensor histidine kinase YP_002810037.1 1355938 D 579112 CDS YP_002810038.1 227081487 7772548 1357256..1357732 1 NC_012578.1 putative chemotaxis protein CheY 1357732 7772548 VCM66_1271 Vibrio cholerae M66-2 putative chemotaxis protein CheY YP_002810038.1 1357256 D 579112 CDS YP_002810039.1 227081488 7772549 complement(1357760..1358680) 1 NC_012578.1 hypothetical protein 1358680 7772549 VCM66_1272 Vibrio cholerae M66-2 hypothetical protein YP_002810039.1 1357760 R 579112 CDS YP_002810040.1 227081489 7772550 complement(1358778..1359551) 1 NC_012578.1 outer membrane protein OmpV 1359551 ompV 7772550 ompV Vibrio cholerae M66-2 outer membrane protein OmpV YP_002810040.1 1358778 R 579112 CDS YP_002810041.1 227081490 7772551 complement(1359764..1361086) 1 NC_012578.1 sensor histidine kinase 1361086 7772551 VCM66_1274 Vibrio cholerae M66-2 sensor histidine kinase YP_002810041.1 1359764 R 579112 CDS YP_002810042.1 227081491 7772552 complement(1361112..1361816) 1 NC_012578.1 DNA-binding response regulator 1361816 7772552 VCM66_1275 Vibrio cholerae M66-2 DNA-binding response regulator YP_002810042.1 1361112 R 579112 CDS YP_002810043.1 227081492 7772553 1362192..1365263 1 NC_012578.1 hypothetical protein 1365263 7772553 VCM66_1276 Vibrio cholerae M66-2 hypothetical protein YP_002810043.1 1362192 D 579112 CDS YP_002810044.1 227081493 7772554 complement(1365344..1365559) 1 NC_012578.1 hypothetical protein 1365559 7772554 VCM66_1277 Vibrio cholerae M66-2 hypothetical protein YP_002810044.1 1365344 R 579112 CDS YP_002810045.1 227081494 7772555 complement(1365538..1366020) 1 NC_012578.1 hypothetical protein 1366020 7772555 VCM66_1278 Vibrio cholerae M66-2 hypothetical protein YP_002810045.1 1365538 R 579112 CDS YP_002810046.1 227081495 7772556 complement(1366385..1366573) 1 NC_012578.1 hypothetical protein 1366573 7772556 VCM66_1279 Vibrio cholerae M66-2 hypothetical protein YP_002810046.1 1366385 R 579112 CDS YP_002810047.1 227081496 7772557 1366519..1367493 1 NC_012578.1 galactoside ABC transporter periplasmic D-galactose/D-glucose-binding protein 1367493 mglB 7772557 mglB Vibrio cholerae M66-2 galactoside ABC transporter periplasmic D-galactose/D-glucose-binding protein YP_002810047.1 1366519 D 579112 CDS YP_002810048.1 227081497 7772558 complement(1367561..1367716) 1 NC_012578.1 hypothetical protein 1367716 7772558 VCM66_1281 Vibrio cholerae M66-2 hypothetical protein YP_002810048.1 1367561 R 579112 CDS YP_002810049.1 227081498 7772559 1367663..1369207 1 NC_012578.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1369207 mglA 7772559 mglA Vibrio cholerae M66-2 galactose/methyl galaxtoside transporter ATP-binding protein YP_002810049.1 1367663 D 579112 CDS YP_002810050.1 227081499 7772560 1369212..1370225 1 NC_012578.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 1370225 mglC 7772560 mglC Vibrio cholerae M66-2 beta-methylgalactoside transporter inner membrane component YP_002810050.1 1369212 D 579112 CDS YP_002810051.1 227081500 7772561 1370635..1371273 1 NC_012578.1 opacity protein-like protein 1371273 7772561 VCM66_1284 Vibrio cholerae M66-2 opacity protein-like protein YP_002810051.1 1370635 D 579112 CDS YP_002810052.1 227081501 7772562 1371594..1372421 1 NC_012578.1 hypothetical protein 1372421 7772562 VCM66_1285 Vibrio cholerae M66-2 hypothetical protein YP_002810052.1 1371594 D 579112 CDS YP_002810053.1 227081502 7772563 complement(1372429..1372557) 1 NC_012578.1 hypothetical protein 1372557 7772563 VCM66_1286 Vibrio cholerae M66-2 hypothetical protein YP_002810053.1 1372429 R 579112 CDS YP_002810054.1 227081503 7772564 complement(1372572..1374101) 1 NC_012578.1 hypothetical protein 1374101 7772564 VCM66_1287 Vibrio cholerae M66-2 hypothetical protein YP_002810054.1 1372572 R 579112 CDS YP_002810055.1 227081504 7772565 complement(1374111..1374662) 1 NC_012578.1 hypothetical protein 1374662 7772565 VCM66_1288 Vibrio cholerae M66-2 hypothetical protein YP_002810055.1 1374111 R 579112 CDS YP_002810056.1 227081505 7772566 complement(1374860..1375831) 1 NC_012578.1 hypothetical protein 1375831 7772566 VCM66_1289 Vibrio cholerae M66-2 hypothetical protein YP_002810056.1 1374860 R 579112 CDS YP_002810057.1 227081506 7772567 1376461..1377168 1 NC_012578.1 GntR family transcriptional regulator 1377168 7772567 VCM66_1290 Vibrio cholerae M66-2 GntR family transcriptional regulator YP_002810057.1 1376461 D 579112 CDS YP_002810058.1 227081507 7772568 1377149..1378075 1 NC_012578.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 1378075 prpB 7772568 prpB Vibrio cholerae M66-2 2-methylisocitrate lyase YP_002810058.1 1377149 D 579112 CDS YP_002810059.1 227081508 7772569 1378251..1379384 1 NC_012578.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 1379384 prpC 7772569 prpC Vibrio cholerae M66-2 methylcitrate synthase YP_002810059.1 1378251 D 579112 CDS YP_002810060.1 227081509 7772570 1379480..1382086 1 NC_012578.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1382086 acnA 7772570 acnA Vibrio cholerae M66-2 aconitate hydratase YP_002810060.1 1379480 D 579112 CDS YP_002810061.1 227081510 7772571 1382095..1383297 1 NC_012578.1 hypothetical protein 1383297 7772571 VCM66_1294 Vibrio cholerae M66-2 hypothetical protein YP_002810061.1 1382095 D 579112 CDS YP_002810062.1 227081511 7772572 1383281..1385179 1 NC_012578.1 prpE protein 1385179 prpE 7772572 prpE Vibrio cholerae M66-2 prpE protein YP_002810062.1 1383281 D 579112 CDS YP_002810063.1 227081512 7772573 1385353..1385829 1 NC_012578.1 putative acetyltransferase 1385829 7772573 VCM66_1296 Vibrio cholerae M66-2 putative acetyltransferase YP_002810063.1 1385353 D 579112 CDS YP_002810064.1 227081513 7772574 1385910..1387307 1 NC_012578.1 MutT/nudix family protein 1387307 7772574 VCM66_1297 Vibrio cholerae M66-2 MutT/nudix family protein YP_002810064.1 1385910 D 579112 CDS YP_002810065.1 227081514 7772575 complement(1387373..1388479) 1 NC_012578.1 peptidase, M20A family 1388479 7772575 VCM66_1298 Vibrio cholerae M66-2 peptidase, M20A family YP_002810065.1 1387373 R 579112 CDS YP_002810066.1 227081515 7772576 1388903..1390012 1 NC_012578.1 4-hydroxyphenylpyruvate dioxygenase 1390012 hppD 7772576 hppD Vibrio cholerae M66-2 4-hydroxyphenylpyruvate dioxygenase YP_002810066.1 1388903 D 579112 CDS YP_002810067.1 227081516 7772577 1390005..1391141 1 NC_012578.1 putative oxidoreductase 1391141 7772577 VCM66_1300 Vibrio cholerae M66-2 putative oxidoreductase YP_002810067.1 1390005 D 579112 CDS YP_002810068.1 227081517 7772578 1391148..1392167 1 NC_012578.1 hypothetical protein 1392167 7772578 VCM66_1301 Vibrio cholerae M66-2 hypothetical protein YP_002810068.1 1391148 D 579112 CDS YP_002810069.1 227081518 7772579 1392164..1392811 1 NC_012578.1 maleylacetoacetate isomerase 1392811 maiA 7772579 maiA Vibrio cholerae M66-2 maleylacetoacetate isomerase YP_002810069.1 1392164 D 579112 CDS YP_002810070.1 227081519 7772580 complement(1392793..1394118) 1 NC_012578.1 response regulator 1394118 7772580 VCM66_1303 Vibrio cholerae M66-2 response regulator YP_002810070.1 1392793 R 579112 CDS YP_002810071.1 227081520 7772581 1394054..1398049 1 NC_012578.1 sensory box sensor histidine kinase/response regulator 1398049 7772581 VCM66_1304 Vibrio cholerae M66-2 sensory box sensor histidine kinase/response regulator YP_002810071.1 1394054 D 579112 CDS YP_002810072.1 227081521 7772582 complement(1398155..1398628) 1 NC_012578.1 putative antioxidant 1398628 7772582 VCM66_1305 Vibrio cholerae M66-2 putative antioxidant YP_002810072.1 1398155 R 579112 CDS YP_002810073.1 227081522 7772583 complement(1398842..1399036) 1 NC_012578.1 hypothetical protein 1399036 7772583 VCM66_1306 Vibrio cholerae M66-2 hypothetical protein YP_002810073.1 1398842 R 579112 CDS YP_002810074.1 227081523 7772584 1399049..1399141 1 NC_012578.1 hypothetical protein 1399141 7772584 VCM66_1307 Vibrio cholerae M66-2 hypothetical protein YP_002810074.1 1399049 D 579112 CDS YP_002810075.1 227081524 7772585 1399279..1402209 1 NC_012578.1 GGDEF family protein 1402209 7772585 VCM66_1308 Vibrio cholerae M66-2 GGDEF family protein YP_002810075.1 1399279 D 579112 CDS YP_002810076.1 227081525 7772586 complement(1402251..1403507) 1 NC_012578.1 hypothetical protein 1403507 7772586 VCM66_1309 Vibrio cholerae M66-2 hypothetical protein YP_002810076.1 1402251 R 579112 CDS YP_002810077.1 227081526 7772587 1403681..1403965 1 NC_012578.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1403965 7772587 VCM66_1310 Vibrio cholerae M66-2 acylphosphatase YP_002810077.1 1403681 D 579112 CDS YP_002810078.1 227081527 7772588 complement(1404031..1404360) 1 NC_012578.1 sulfite reductase subunit gamma-like protein 1404360 7772588 VCM66_1311 Vibrio cholerae M66-2 sulfite reductase subunit gamma-like protein YP_002810078.1 1404031 R 579112 CDS YP_002810079.1 227081528 7772589 complement(1404326..1404445) 1 NC_012578.1 hypothetical protein 1404445 7772589 VCM66_1312 Vibrio cholerae M66-2 hypothetical protein YP_002810079.1 1404326 R 579112 CDS YP_002810080.1 227081529 7772590 complement(1404474..1405145) 1 NC_012578.1 hypothetical protein 1405145 7772590 VCM66_1313 Vibrio cholerae M66-2 hypothetical protein YP_002810080.1 1404474 R 579112 CDS YP_002810081.1 227081530 7772591 complement(1405390..1406145) 1 NC_012578.1 amino acid ABC transporter ATP-binding protein 1406145 7772591 VCM66_1314 Vibrio cholerae M66-2 amino acid ABC transporter ATP-binding protein YP_002810081.1 1405390 R 579112 CDS YP_002810082.1 227081531 7772592 complement(1406168..1407265) 1 NC_012578.1 amino acid ABC transporter permease 1407265 7772592 VCM66_1315 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002810082.1 1406168 R 579112 CDS YP_002810083.1 227081532 7772593 complement(1407268..1408473) 1 NC_012578.1 amino acid ABC transporter permease 1408473 7772593 VCM66_1316 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002810083.1 1407268 R 579112 CDS YP_002810084.1 227081533 7772594 complement(1408599..1409627) 1 NC_012578.1 amino acid ABC transporter substrate-binding protein 1409627 7772594 VCM66_1317 Vibrio cholerae M66-2 amino acid ABC transporter substrate-binding protein YP_002810084.1 1408599 R 579112 CDS YP_002810085.1 227081534 7772595 1410082..1411020 1 NC_012578.1 siroheme synthase component protein 1411020 7772595 VCM66_1318 Vibrio cholerae M66-2 siroheme synthase component protein YP_002810085.1 1410082 D 579112 CDS YP_002810086.1 227081535 7772596 complement(1411086..1411907) 1 NC_012578.1 putative phosphatase 1411907 7772596 VCM66_1319 Vibrio cholerae M66-2 putative phosphatase YP_002810086.1 1411086 R 579112 CDS YP_002810087.1 227081536 7772597 1412183..1412920 1 NC_012578.1 hypothetical protein 1412920 7772597 VCM66_1320 Vibrio cholerae M66-2 hypothetical protein YP_002810087.1 1412183 D 579112 CDS YP_002810088.1 227081537 7772598 1412933..1413628 1 NC_012578.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 1413628 exsB 7772598 exsB Vibrio cholerae M66-2 queuosine biosynthesis protein QueC YP_002810088.1 1412933 D 579112 CDS YP_002810089.1 227081538 7772599 complement(1413600..1415603) 1 NC_012578.1 GGDEF family protein 1415603 7772599 VCM66_1322 Vibrio cholerae M66-2 GGDEF family protein YP_002810089.1 1413600 R 579112 CDS YP_002810090.1 227081539 7772600 1415774..1416022 1 NC_012578.1 hypothetical protein 1416022 7772600 VCM66_1323 Vibrio cholerae M66-2 hypothetical protein YP_002810090.1 1415774 D 579112 CDS YP_002810091.1 227081540 7772601 1416179..1417195 1 NC_012578.1 hypothetical protein 1417195 7772601 VCM66_1324 Vibrio cholerae M66-2 hypothetical protein YP_002810091.1 1416179 D 579112 CDS YP_002810092.1 227081541 7772602 1417192..1418523 1 NC_012578.1 GGDEF family protein 1418523 7772602 VCM66_1325 Vibrio cholerae M66-2 GGDEF family protein YP_002810092.1 1417192 D 579112 CDS YP_002810093.1 227081542 7772603 complement(1418574..1419254) 1 NC_012578.1 hypothetical protein 1419254 7772603 VCM66_1326 Vibrio cholerae M66-2 hypothetical protein YP_002810093.1 1418574 R 579112 CDS YP_002810094.1 227081543 7772604 1419628..1420806 1 NC_012578.1 GGDEF family protein 1420806 7772604 VCM66_1327 Vibrio cholerae M66-2 GGDEF family protein YP_002810094.1 1419628 D 579112 CDS YP_002810095.1 227081544 7772605 complement(1420918..1423764) 1 NC_012578.1 DnaK-like protein 1423764 7772605 VCM66_1328 Vibrio cholerae M66-2 DnaK-like protein YP_002810095.1 1420918 R 579112 CDS YP_002810096.1 227081545 7772606 complement(1423806..1425701) 1 NC_012578.1 DnaK-like protein 1425701 7772606 VCM66_1329 Vibrio cholerae M66-2 DnaK-like protein YP_002810096.1 1423806 R 579112 CDS YP_002810097.1 227081546 7772607 complement(1425701..1426429) 1 NC_012578.1 hypothetical protein 1426429 7772607 VCM66_1330 Vibrio cholerae M66-2 hypothetical protein YP_002810097.1 1425701 R 579112 CDS YP_002810098.1 227081547 7772608 1426841..1428454 1 NC_012578.1 GGDEF family protein 1428454 7772608 VCM66_1331 Vibrio cholerae M66-2 GGDEF family protein YP_002810098.1 1426841 D 579112 CDS YP_002810099.1 227081548 7772609 1428472..1429002 1 NC_012578.1 hypothetical protein 1429002 7772609 VCM66_1332 Vibrio cholerae M66-2 hypothetical protein YP_002810099.1 1428472 D 579112 CDS YP_002810100.1 227081549 7772610 1429004..1429186 1 NC_012578.1 hypothetical protein 1429186 7772610 VCM66_1333 Vibrio cholerae M66-2 hypothetical protein YP_002810100.1 1429004 D 579112 CDS YP_002810101.1 227081550 7772611 complement(1429288..1429752) 1 NC_012578.1 hypothetical protein 1429752 7772611 VCM66_1334 Vibrio cholerae M66-2 hypothetical protein YP_002810101.1 1429288 R 579112 CDS YP_002810102.1 227081551 7772612 complement(1429799..1430149) 1 NC_012578.1 hypothetical protein 1430149 7772612 VCM66_1335 Vibrio cholerae M66-2 hypothetical protein YP_002810102.1 1429799 R 579112 CDS YP_002810103.1 227081552 7772613 complement(1430184..1430393) 1 NC_012578.1 hypothetical protein 1430393 7772613 VCM66_1336 Vibrio cholerae M66-2 hypothetical protein YP_002810103.1 1430184 R 579112 CDS YP_002810104.1 227081553 7772614 1430351..1434280 1 NC_012578.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1434280 hrpA 7772614 hrpA Vibrio cholerae M66-2 ATP-dependent RNA helicase HrpA YP_002810104.1 1430351 D 579112 CDS YP_002810105.1 227081554 7772615 complement(1434258..1434389) 1 NC_012578.1 hypothetical protein 1434389 7772615 VCM66_1338 Vibrio cholerae M66-2 hypothetical protein YP_002810105.1 1434258 R 579112 CDS YP_002810106.1 227081555 7772616 1434420..1434902 1 NC_012578.1 hypothetical protein 1434902 7772616 VCM66_1339 Vibrio cholerae M66-2 hypothetical protein YP_002810106.1 1434420 D 579112 CDS YP_002810107.1 227081556 7772617 complement(1434935..1435045) 1 NC_012578.1 hypothetical protein 1435045 7772617 VCM66_1340 Vibrio cholerae M66-2 hypothetical protein YP_002810107.1 1434935 R 579112 CDS YP_002810108.1 227081557 7772618 1435119..1436471 1 NC_012578.1 putative chaperone 1436471 7772618 VCM66_1341 Vibrio cholerae M66-2 putative chaperone YP_002810108.1 1435119 D 579112 CDS YP_002810109.1 227081558 7772619 1436505..1436603 1 NC_012578.1 hypothetical protein 1436603 7772619 VCM66_1342 Vibrio cholerae M66-2 hypothetical protein YP_002810109.1 1436505 D 579112 CDS YP_002810110.1 227081559 7772620 1436596..1437612 1 NC_012578.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 1437612 lplA 7772620 lplA Vibrio cholerae M66-2 lipoate-protein ligase A YP_002810110.1 1436596 D 579112 CDS YP_002810111.1 227081560 7772621 1437848..1438027 1 NC_012578.1 hypothetical protein 1438027 7772621 VCM66_1344 Vibrio cholerae M66-2 hypothetical protein YP_002810111.1 1437848 D 579112 CDS YP_002810112.1 227081561 7772622 complement(1438005..1438955) 1 NC_012578.1 LysR family transcriptional regulator 1438955 7772622 VCM66_1345 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810112.1 1438005 R 579112 CDS YP_002810113.1 227081562 7772623 1439042..1440448 1 NC_012578.1 putative multidrug transporter 1440448 7772623 VCM66_1346 Vibrio cholerae M66-2 putative multidrug transporter YP_002810113.1 1439042 D 579112 CDS YP_002810114.1 227081563 7772624 1440604..1442118 1 NC_012578.1 putative deoxyribodipyrimidine photolyase 1442118 7772624 VCM66_1347 Vibrio cholerae M66-2 putative deoxyribodipyrimidine photolyase YP_002810114.1 1440604 D 579112 CDS YP_002810115.1 227081564 7772625 1442264..1442578 1 NC_012578.1 sugE protein 1442578 sugE 7772625 sugE Vibrio cholerae M66-2 sugE protein YP_002810115.1 1442264 D 579112 CDS YP_002810116.1 227081565 7772626 complement(1442633..1443868) 1 NC_012578.1 methyl-accepting chemotaxis protein 1443868 7772626 VCM66_1349 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810116.1 1442633 R 579112 CDS YP_002810117.1 227081566 7772627 complement(1443876..1444256) 1 NC_012578.1 chemotaxis protein CheY 1444256 cheY-1 7772627 cheY-1 Vibrio cholerae M66-2 chemotaxis protein CheY YP_002810117.1 1443876 R 579112 CDS YP_002810118.1 227081567 7772628 complement(1444249..1444509) 1 NC_012578.1 hypothetical protein 1444509 7772628 VCM66_1351 Vibrio cholerae M66-2 hypothetical protein YP_002810118.1 1444249 R 579112 CDS YP_002810119.1 227081568 7772629 complement(1444499..1446784) 1 NC_012578.1 chemotaxis protein CheA 1446784 cheA-1 7772629 cheA-1 Vibrio cholerae M66-2 chemotaxis protein CheA YP_002810119.1 1444499 R 579112 CDS YP_002810120.1 227081569 7772630 complement(1446781..1447155) 1 NC_012578.1 chemotaxis protein CheY 1447155 cheY-2 7772630 cheY-2 Vibrio cholerae M66-2 chemotaxis protein CheY YP_002810120.1 1446781 R 579112 CDS YP_002810121.1 227081570 7772631 complement(1447152..1447997) 1 NC_012578.1 chemotaxis protein methyltransferase CheR 1447997 cheR-1 7772631 cheR-1 Vibrio cholerae M66-2 chemotaxis protein methyltransferase CheR YP_002810121.1 1447152 R 579112 CDS YP_002810122.1 227081571 7772632 complement(1448008..1448664) 1 NC_012578.1 hypothetical protein 1448664 7772632 VCM66_1355 Vibrio cholerae M66-2 hypothetical protein YP_002810122.1 1448008 R 579112 CDS YP_002810123.1 227081572 7772633 complement(1448651..1449727) 1 NC_012578.1 protein-glutamate methylesterase CheB 1449727 cheB-1 7772633 cheB-1 Vibrio cholerae M66-2 protein-glutamate methylesterase CheB YP_002810123.1 1448651 R 579112 CDS YP_002810124.1 227081573 7772634 complement(1449748..1451310) 1 NC_012578.1 putative purine-binding chemotaxis protein Chew 1451310 7772634 VCM66_1357 Vibrio cholerae M66-2 putative purine-binding chemotaxis protein Chew YP_002810124.1 1449748 R 579112 CDS YP_002810125.1 227081574 7772635 complement(1451323..1453248) 1 NC_012578.1 methyl-accepting chemotaxis protein 1453248 7772635 VCM66_1358 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810125.1 1451323 R 579112 CDS YP_002810126.1 227081575 7772636 complement(1453382..1453504) 1 NC_012578.1 hypothetical protein 1453504 7772636 VCM66_1359 Vibrio cholerae M66-2 hypothetical protein YP_002810126.1 1453382 R 579112 CDS YP_002810127.1 227081576 7772637 1453744..1455531 1 NC_012578.1 methyl-accepting chemotaxis protein 1455531 7772637 VCM66_1360 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810127.1 1453744 D 579112 CDS YP_002810128.1 227081577 7772638 1455610..1456926 1 NC_012578.1 methyl-accepting chemotaxis protein 1456926 7772638 VCM66_1361 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810128.1 1455610 D 579112 CDS YP_002810129.1 227081578 7772639 1457108..1458301 1 NC_012578.1 ATP-dependent RNA helicase RhlE 1458301 rhlE-1 7772639 rhlE-1 Vibrio cholerae M66-2 ATP-dependent RNA helicase RhlE YP_002810129.1 1457108 D 579112 CDS YP_002810130.1 227081579 7772640 complement(1458360..1458962) 1 NC_012578.1 TetR family transcriptional regulator 1458962 7772640 VCM66_1363 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002810130.1 1458360 R 579112 CDS YP_002810131.1 227081580 7772641 1459069..1460523 1 NC_012578.1 putative multidrug resistance protein 1460523 7772641 VCM66_1364 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002810131.1 1459069 D 579112 CDS YP_002810132.1 227081581 7772642 1460504..1461724 1 NC_012578.1 multidrug resistance protein VceA 1461724 vceA 7772642 vceA Vibrio cholerae M66-2 multidrug resistance protein VceA YP_002810132.1 1460504 D 579112 CDS YP_002810133.1 227081582 7772643 1461734..1463269 1 NC_012578.1 multidrug resistance protein VceB 1463269 vceB 7772643 vceB Vibrio cholerae M66-2 multidrug resistance protein VceB YP_002810133.1 1461734 D 579112 CDS YP_002810134.1 227081583 7772644 1463223..1463339 1 NC_012578.1 hypothetical protein 1463339 7772644 VCM66_1367 Vibrio cholerae M66-2 hypothetical protein YP_002810134.1 1463223 D 579112 CDS YP_002810135.1 227081584 7772645 complement(1463344..1465080) 1 NC_012578.1 methyl-accepting chemotaxis protein 1465080 7772645 VCM66_1368 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810135.1 1463344 R 579112 CDS YP_002810136.1 227081585 7772646 complement(1465302..1466876) 1 NC_012578.1 thermostable carboxypeptidase 1 1466876 7772646 VCM66_1369 Vibrio cholerae M66-2 thermostable carboxypeptidase 1 YP_002810136.1 1465302 R 579112 CDS YP_002810137.1 227081586 7772647 1467074..1467592 1 NC_012578.1 hcp protein 1467592 hcp-1 7772647 hcp-1 Vibrio cholerae M66-2 hcp protein YP_002810137.1 1467074 D 579112 CDS YP_002810138.1 227081587 7772648 1467720..1471211 1 NC_012578.1 vgrG protein 1471211 vgrG-1 7772648 vgrG-1 Vibrio cholerae M66-2 vgrG protein YP_002810138.1 1467720 D 579112 CDS YP_002810139.1 227081588 7772649 1471190..1472050 1 NC_012578.1 hypothetical protein 1472050 7772649 VCM66_1372 Vibrio cholerae M66-2 hypothetical protein YP_002810139.1 1471190 D 579112 CDS YP_002810140.1 227081589 7772650 1472053..1473978 1 NC_012578.1 hypothetical protein 1473978 7772650 VCM66_1373 Vibrio cholerae M66-2 hypothetical protein YP_002810140.1 1472053 D 579112 CDS YP_002810141.1 227081590 7772651 1473975..1474718 1 NC_012578.1 hypothetical protein 1474718 7772651 VCM66_1374 Vibrio cholerae M66-2 hypothetical protein YP_002810141.1 1473975 D 579112 CDS YP_002810142.1 227081591 7772652 1474863..1475600 1 NC_012578.1 hypothetical protein 1475600 7772652 VCM66_1375 Vibrio cholerae M66-2 hypothetical protein YP_002810142.1 1474863 D 579112 CDS YP_002810143.1 227081592 7772653 1475688..1476326 1 NC_012578.1 hypothetical protein 1476326 7772653 VCM66_1376 Vibrio cholerae M66-2 hypothetical protein YP_002810143.1 1475688 D 579112 CDS YP_002810144.1 227081593 7772654 complement(1476399..1477775) 1 NC_012578.1 sodium/alanine symporter 1477775 7772654 VCM66_1377 Vibrio cholerae M66-2 sodium/alanine symporter YP_002810144.1 1476399 R 579112 CDS YP_002810145.1 227081594 7772655 1478278..1478436 1 NC_012578.1 hypothetical protein 1478436 7772655 VCM66_1378 Vibrio cholerae M66-2 hypothetical protein YP_002810145.1 1478278 D 579112 CDS YP_002810146.1 227081595 7772656 1478453..1479187 1 NC_012578.1 hypothetical protein 1479187 7772656 VCM66_1379 Vibrio cholerae M66-2 hypothetical protein YP_002810146.1 1478453 D 579112 CDS YP_002810147.1 227081596 7772657 complement(1479334..1480371) 1 NC_012578.1 spermidine/putrescine ABC transporter substrate-binding protein 1480371 potD-1 7772657 potD-1 Vibrio cholerae M66-2 spermidine/putrescine ABC transporter substrate-binding protein YP_002810147.1 1479334 R 579112 CDS YP_002810148.1 227081597 7772658 complement(1480483..1481583) 1 NC_012578.1 spermidine/putrescine ABC transporter substrate-binding protein 1481583 potD-2 7772658 potD-2 Vibrio cholerae M66-2 spermidine/putrescine ABC transporter substrate-binding protein YP_002810148.1 1480483 R 579112 CDS YP_002810149.1 227081598 7772659 complement(1481617..1482387) 1 NC_012578.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1482387 potC 7772659 potC Vibrio cholerae M66-2 spermidine/putrescine ABC transporter membrane protein YP_002810149.1 1481617 R 579112 CDS YP_002810150.1 227081599 7772660 complement(1482387..1483247) 1 NC_012578.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1483247 potB 7772660 potB Vibrio cholerae M66-2 spermidine/putrescine ABC transporter membrane protein YP_002810150.1 1482387 R 579112 CDS YP_002810151.1 227081600 7772661 complement(1483228..1484361) 1 NC_012578.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1484361 potA 7772661 potA Vibrio cholerae M66-2 putrescine/spermidine ABC transporter ATPase protein YP_002810151.1 1483228 R 579112 CDS YP_002810152.1 227081601 7772662 1484647..1485492 1 NC_012578.1 hypothetical protein 1485492 7772662 VCM66_1385 Vibrio cholerae M66-2 hypothetical protein YP_002810152.1 1484647 D 579112 CDS YP_002810153.1 227081602 7772663 1485482..1486285 1 NC_012578.1 putative bax protein 1486285 7772663 VCM66_1386 Vibrio cholerae M66-2 putative bax protein YP_002810153.1 1485482 D 579112 CDS YP_002810154.1 227081603 7772664 1486287..1486946 1 NC_012578.1 hypothetical protein 1486946 7772664 VCM66_1387 Vibrio cholerae M66-2 hypothetical protein YP_002810154.1 1486287 D 579112 CDS YP_002810155.1 227081604 7772665 complement(1487023..1487955) 1 NC_012578.1 hypothetical protein 1487955 7772665 VCM66_1388 Vibrio cholerae M66-2 hypothetical protein YP_002810155.1 1487023 R 579112 CDS YP_002810156.1 227081605 7772666 complement(1488082..1489029) 1 NC_012578.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1489029 7772666 VCM66_1389 Vibrio cholerae M66-2 universal stress protein UspE YP_002810156.1 1488082 R 579112 CDS YP_002810157.1 227081606 7772667 complement(1489159..1489911) 1 NC_012578.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1489911 fnr 7772667 fnr Vibrio cholerae M66-2 fumarate/nitrate reduction transcriptional regulator YP_002810157.1 1489159 R 579112 CDS YP_002810158.1 227081607 7772668 complement(1490001..1490675) 1 NC_012578.1 hypothetical protein 1490675 7772668 VCM66_1391 Vibrio cholerae M66-2 hypothetical protein YP_002810158.1 1490001 R 579112 CDS YP_002810159.1 227081608 7772669 complement(1490672..1490836) 1 NC_012578.1 FixS-like protein 1490836 7772669 VCM66_1392 Vibrio cholerae M66-2 FixS-like protein YP_002810159.1 1490672 R 579112 CDS YP_002810160.1 227081609 7772670 complement(1490840..1493212) 1 NC_012578.1 cation transport ATPase, E1-E2 family 1493212 7772670 VCM66_1393 Vibrio cholerae M66-2 cation transport ATPase, E1-E2 family YP_002810160.1 1490840 R 579112 CDS YP_002810161.1 227081610 7772671 complement(1493217..1493693) 1 NC_012578.1 hypothetical protein 1493693 7772671 VCM66_1394 Vibrio cholerae M66-2 hypothetical protein YP_002810161.1 1493217 R 579112 CDS YP_002810162.1 227081611 7772672 complement(1493772..1494752) 1 NC_012578.1 cytochrome c oxidase subunit CcoP 1494752 ccoP 7772672 ccoP Vibrio cholerae M66-2 cytochrome c oxidase subunit CcoP YP_002810162.1 1493772 R 579112 CDS YP_002810163.1 227081612 7772673 complement(1494760..1494924) 1 NC_012578.1 cytochrome c oxidase subunit CcoQ 1494924 ccoQ 7772673 ccoQ Vibrio cholerae M66-2 cytochrome c oxidase subunit CcoQ YP_002810163.1 1494760 R 579112 CDS YP_002810164.1 227081613 7772674 complement(1494936..1495556) 1 NC_012578.1 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 1495556 ccoO 7772674 ccoO Vibrio cholerae M66-2 cbb3-type cytochrome c oxidase subunit II YP_002810164.1 1494936 R 579112 CDS YP_002810165.1 227081614 7772675 complement(1495570..1497003) 1 NC_012578.1 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 1497003 ccoN 7772675 ccoN Vibrio cholerae M66-2 cbb3-type cytochrome c oxidase subunit I YP_002810165.1 1495570 R 579112 CDS YP_002810166.1 227081615 7772676 1497232..1497612 1 NC_012578.1 hypothetical protein 1497612 7772676 VCM66_1399 Vibrio cholerae M66-2 hypothetical protein YP_002810166.1 1497232 D 579112 CDS YP_002810167.1 227081616 7772677 1497681..1498898 1 NC_012578.1 hypothetical protein 1498898 7772677 VCM66_1400 Vibrio cholerae M66-2 hypothetical protein YP_002810167.1 1497681 D 579112 CDS YP_002810168.1 227081617 7772678 1498895..1500613 1 NC_012578.1 sensor histidine kinase/response regulator 1500613 7772678 VCM66_1401 Vibrio cholerae M66-2 sensor histidine kinase/response regulator YP_002810168.1 1498895 D 579112 CDS YP_002810169.1 227081618 7772679 complement(1500674..1502839) 1 NC_012578.1 putative toxin secretion transporter 1502839 7772679 VCM66_1402 Vibrio cholerae M66-2 putative toxin secretion transporter YP_002810169.1 1500674 R 579112 CDS YP_002810170.1 227081619 7772680 complement(1502842..1504245) 1 NC_012578.1 RTX toxin transporter 1504245 rtxD 7772680 rtxD Vibrio cholerae M66-2 RTX toxin transporter YP_002810170.1 1502842 R 579112 CDS YP_002810171.1 227081620 7772681 complement(1504200..1506362) 1 NC_012578.1 RTX toxin transporter 1506362 rtxB 7772681 rtxB Vibrio cholerae M66-2 RTX toxin transporter YP_002810171.1 1504200 R 579112 CDS YP_002810172.1 227081621 7772682 1506720..1507079 1 NC_012578.1 hypothetical protein 1507079 7772682 VCM66_1405 Vibrio cholerae M66-2 hypothetical protein YP_002810172.1 1506720 D 579112 CDS YP_002810173.1 227081622 7772683 1507105..1507566 1 NC_012578.1 RTX toxin activating protein 1507566 7772683 VCM66_1406 Vibrio cholerae M66-2 RTX toxin activating protein YP_002810173.1 1507105 D 579112 CDS YP_002810174.1 227081623 7772684 1507551..1521227 1 NC_012578.1 RTX toxin RtxA 1521227 rtxA 7772684 rtxA Vibrio cholerae M66-2 RTX toxin RtxA YP_002810174.1 1507551 D 579112 CDS YP_002810175.1 227081624 7772685 complement(1521573..1522157) 1 NC_012578.1 hypothetical protein 1522157 7772685 VCM66_1408 Vibrio cholerae M66-2 hypothetical protein YP_002810175.1 1521573 R 579112 CDS YP_002810176.1 227081625 7772686 complement(1522150..1522317) 1 NC_012578.1 hypothetical protein 1522317 7772686 VCM66_1409 Vibrio cholerae M66-2 hypothetical protein YP_002810176.1 1522150 R 579112 CDS YP_002810177.1 227081626 7772687 complement(1522395..1523087) 1 NC_012578.1 hypothetical protein 1523087 7772687 VCM66_1410 Vibrio cholerae M66-2 hypothetical protein YP_002810177.1 1522395 R 579112 CDS YP_002810178.1 227081627 7772688 complement(1523217..1523501) 1 NC_012578.1 hypothetical protein 1523501 7772688 VCM66_1411 Vibrio cholerae M66-2 hypothetical protein YP_002810178.1 1523217 R 579112 CDS YP_002810179.1 227081628 7772689 complement(1523506..1525074) 1 NC_012578.1 phage replication protein Cri 1525074 cri-1 7772689 cri-1 Vibrio cholerae M66-2 phage replication protein Cri YP_002810179.1 1523506 R 579112 CDS YP_002810180.1 227081629 7772690 1525236..1525802 1 NC_012578.1 tlcR protein 1525802 tlcR 7772690 tlcR Vibrio cholerae M66-2 tlcR protein YP_002810180.1 1525236 D 579112 CDS YP_002810181.1 227081630 7772691 complement(1526841..1527008) 1 NC_012578.1 hypothetical protein 1527008 7772691 VCM66_1414 Vibrio cholerae M66-2 hypothetical protein YP_002810181.1 1526841 R 579112 CDS YP_002810182.1 227081631 7772692 complement(1527001..1527168) 1 NC_012578.1 hypothetical protein 1527168 7772692 VCM66_1415 Vibrio cholerae M66-2 hypothetical protein YP_002810182.1 1527001 R 579112 CDS YP_002810183.1 227081632 7772693 complement(1527246..1527938) 1 NC_012578.1 hypothetical protein 1527938 7772693 VCM66_1416 Vibrio cholerae M66-2 hypothetical protein YP_002810183.1 1527246 R 579112 CDS YP_002810184.1 227081633 7772694 complement(1528068..1528352) 1 NC_012578.1 hypothetical protein 1528352 7772694 VCM66_1417 Vibrio cholerae M66-2 hypothetical protein YP_002810184.1 1528068 R 579112 CDS YP_002810185.1 227081634 7772695 complement(1528357..1529925) 1 NC_012578.1 phage replication protein Cri 1529925 cri-2 7772695 cri-2 Vibrio cholerae M66-2 phage replication protein Cri YP_002810185.1 1528357 R 579112 CDS YP_002810186.1 227081635 7772696 1530087..1530653 1 NC_012578.1 tlcR protein 1530653 tlcR 7772696 tlcR Vibrio cholerae M66-2 tlcR protein YP_002810186.1 1530087 D 579112 CDS YP_002810187.1 227081636 7772697 1530962..1531315 1 NC_012578.1 ISVch4 transposase, OrfA 1531315 7772697 VCM66_1420 Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002810187.1 1530962 D 579112 CDS YP_002810188.1 227081637 7772698 1531312..1532184 1 NC_012578.1 ISVch4 transposase, OrfB 1532184 7772698 VCM66_1421 Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002810188.1 1531312 D 579112 CDS YP_002810189.1 227081638 7772699 complement(1533093..1533452) 1 NC_012578.1 hypothetical protein 1533452 7772699 VCM66_1422 Vibrio cholerae M66-2 hypothetical protein YP_002810189.1 1533093 R 579112 CDS YP_002810190.1 227081639 7772700 complement(1533563..1533895) 1 NC_012578.1 hypothetical protein 1533895 7772700 VCM66_1423 Vibrio cholerae M66-2 hypothetical protein YP_002810190.1 1533563 R 579112 CDS YP_002810191.1 227081640 7772701 complement(1533900..1534409) 1 NC_012578.1 hypothetical protein 1534409 7772701 VCM66_1424 Vibrio cholerae M66-2 hypothetical protein YP_002810191.1 1533900 R 579112 CDS YP_002810192.1 227081641 7772702 1534366..1536162 1 NC_012578.1 ATP-dependent protease LA-like protein 1536162 7772702 VCM66_1425 Vibrio cholerae M66-2 ATP-dependent protease LA-like protein YP_002810192.1 1534366 D 579112 CDS YP_002810193.1 227081642 7772703 1536227..1536745 1 NC_012578.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 1536745 fabA 7772703 fabA Vibrio cholerae M66-2 3-hydroxydecanoyl-(acyl carrier protein) dehydratase YP_002810193.1 1536227 D 579112 CDS YP_002810194.1 227081643 7772704 complement(1536828..1537001) 1 NC_012578.1 ribosome modulation factor 1537001 rmf 7772704 rmf Vibrio cholerae M66-2 ribosome modulation factor YP_002810194.1 1536828 R 579112 CDS YP_002810195.1 227081644 7772705 complement(1537168..1538862) 1 NC_012578.1 hypothetical protein 1538862 7772705 VCM66_1428 Vibrio cholerae M66-2 hypothetical protein YP_002810195.1 1537168 R 579112 CDS YP_002810196.1 227081645 7772706 complement(1538868..1540787) 1 NC_012578.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1540787 7772706 VCM66_1429 Vibrio cholerae M66-2 ABC transporter ATPase YP_002810196.1 1538868 R 579112 CDS YP_002810197.1 227081646 7772707 complement(1540765..1541007) 1 NC_012578.1 hypothetical protein 1541007 7772707 VCM66_1430 Vibrio cholerae M66-2 hypothetical protein YP_002810197.1 1540765 R 579112 CDS YP_002810198.1 227081647 7772708 complement(1541016..1543142) 1 NC_012578.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1543142 rlmL 7772708 rlmL Vibrio cholerae M66-2 23S rRNA m(2)G2445 methyltransferase YP_002810198.1 1541016 R 579112 CDS YP_002810199.1 227081648 7772709 complement(1543401..1543532) 1 NC_012578.1 hypothetical protein 1543532 7772709 VCM66_1432 Vibrio cholerae M66-2 hypothetical protein YP_002810199.1 1543401 R 579112 CDS YP_002810200.1 227081649 7772710 complement(1543602..1544144) 1 NC_012578.1 hypothetical protein 1544144 7772710 VCM66_1433 Vibrio cholerae M66-2 hypothetical protein YP_002810200.1 1543602 R 579112 CDS YP_002810201.1 227081650 7772711 complement(1544299..1545309) 1 NC_012578.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1545309 pyrD 7772711 pyrD Vibrio cholerae M66-2 dihydroorotate dehydrogenase 2 YP_002810201.1 1544299 R 579112 CDS YP_002810202.1 227081651 7772712 complement(1545383..1550224) 1 NC_012578.1 hypothetical protein 1550224 7772712 VCM66_1435 Vibrio cholerae M66-2 hypothetical protein YP_002810202.1 1545383 R 579112 CDS YP_002810203.1 227081652 7772713 complement(1550413..1550649) 1 NC_012578.1 hypothetical protein 1550649 7772713 VCM66_1436 Vibrio cholerae M66-2 hypothetical protein YP_002810203.1 1550413 R 579112 CDS YP_002810204.1 227081653 7772714 complement(1550683..1553289) 1 NC_012578.1 aminopeptidase N 1553289 pepN 7772714 pepN Vibrio cholerae M66-2 aminopeptidase N YP_002810204.1 1550683 R 579112 CDS YP_002810205.1 227081654 7772715 complement(1553488..1554204) 1 NC_012578.1 hypothetical protein 1554204 7772715 VCM66_1438 Vibrio cholerae M66-2 hypothetical protein YP_002810205.1 1553488 R 579112 CDS YP_002810206.1 227081655 7772716 complement(1554313..1556310) 1 NC_012578.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1556310 prc 7772716 prc Vibrio cholerae M66-2 carboxy-terminal protease YP_002810206.1 1554313 R 579112 CDS YP_002810207.1 227081656 7772717 complement(1556328..1556954) 1 NC_012578.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 1556954 7772717 VCM66_1440 Vibrio cholerae M66-2 putative solute/DNA competence effector YP_002810207.1 1556328 R 579112 CDS YP_002810208.1 227081657 7772718 complement(1557055..1557633) 1 NC_012578.1 GAF family protein 1557633 7772718 VCM66_1441 Vibrio cholerae M66-2 GAF family protein YP_002810208.1 1557055 R 579112 CDS YP_002810209.1 227081658 7772719 1557578..1559410 1 NC_012578.1 ABC transporter ATP-binding protein 1559410 7772719 VCM66_1442 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810209.1 1557578 D 579112 CDS YP_002810210.1 227081659 7772720 1559444..1560703 1 NC_012578.1 PqiA family protein 1560703 7772720 VCM66_1443 Vibrio cholerae M66-2 PqiA family protein YP_002810210.1 1559444 D 579112 CDS YP_002810211.1 227081660 7772721 1560713..1563352 1 NC_012578.1 hypothetical protein 1563352 7772721 VCM66_1444 Vibrio cholerae M66-2 hypothetical protein YP_002810211.1 1560713 D 579112 CDS YP_002810212.1 227081661 7772722 1563383..1564894 1 NC_012578.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1564894 yebU 7772722 yebU Vibrio cholerae M66-2 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_002810212.1 1563383 D 579112 CDS YP_002810213.1 227081662 7772723 complement(1565076..1565972) 1 NC_012578.1 hypothetical protein 1565972 7772723 VCM66_1446 Vibrio cholerae M66-2 hypothetical protein YP_002810213.1 1565076 R 579112 CDS YP_002810214.1 227081663 7772724 1566011..1567360 1 NC_012578.1 hypothetical protein 1567360 7772724 VCM66_1447 Vibrio cholerae M66-2 hypothetical protein YP_002810214.1 1566011 D 579112 CDS YP_002810215.1 227081664 7772725 complement(1567353..1567829) 1 NC_012578.1 hypothetical protein 1567829 7772725 VCM66_1448 Vibrio cholerae M66-2 hypothetical protein YP_002810215.1 1567353 R 579112 CDS YP_002810216.1 227081665 7772726 1567979..1569166 1 NC_012578.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1569166 aroH 7772726 aroH Vibrio cholerae M66-2 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002810216.1 1567979 D 579112 CDS YP_002810217.1 227081666 7772727 1569178..1569660 1 NC_012578.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 1569660 7772727 VCM66_1450 Vibrio cholerae M66-2 putative nucleotide-binding protein YP_002810217.1 1569178 D 579112 CDS YP_002810218.1 227081667 7772728 complement(1569795..1570574) 1 NC_012578.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1570574 cobB 7772728 cobB Vibrio cholerae M66-2 NAD-dependent deacetylase YP_002810218.1 1569795 R 579112 CDS YP_002810219.1 227081668 7772729 complement(1570672..1571094) 1 NC_012578.1 hypothetical protein 1571094 7772729 VCM66_1452 Vibrio cholerae M66-2 hypothetical protein YP_002810219.1 1570672 R 579112 CDS YP_002810220.1 227081669 7772730 complement(1571081..1572154) 1 NC_012578.1 formate dehydrogenase, cytochrome B556 subunit 1572154 fdnI 7772730 fdnI Vibrio cholerae M66-2 formate dehydrogenase, cytochrome B556 subunit YP_002810220.1 1571081 R 579112 CDS YP_002810221.1 227081670 7772731 complement(1572155..1572763) 1 NC_012578.1 formate dehydrogenase, iron-sulfur subunit 1572763 fdhB 7772731 fdhB Vibrio cholerae M66-2 formate dehydrogenase, iron-sulfur subunit YP_002810221.1 1572155 R 579112 CDS YP_002810222.1 227081671 7772732 complement(1572775..1575630) 1 NC_012578.1 putative formate dehydrogenase subunit alpha 1575630 7772732 VCM66_1455 Vibrio cholerae M66-2 putative formate dehydrogenase subunit alpha YP_002810222.1 1572775 R 579112 CDS YP_002810223.1 227081672 7772733 complement(1575642..1575839) 1 NC_012578.1 hypothetical protein 1575839 7772733 VCM66_1456 Vibrio cholerae M66-2 hypothetical protein YP_002810223.1 1575642 R 579112 CDS YP_002810224.1 227081673 7772734 complement(1575917..1576573) 1 NC_012578.1 putative chaperone, formate dehydrogenase-specific 1576573 7772734 VCM66_1457 Vibrio cholerae M66-2 putative chaperone, formate dehydrogenase-specific YP_002810224.1 1575917 R 579112 CDS YP_002810225.1 227081674 7772735 complement(1576599..1578260) 1 NC_012578.1 iron-sulfur cluster-binding protein 1578260 7772735 VCM66_1458 Vibrio cholerae M66-2 iron-sulfur cluster-binding protein YP_002810225.1 1576599 R 579112 CDS YP_002810226.1 227081675 7772736 complement(1578459..1579124) 1 NC_012578.1 hypothetical protein 1579124 7772736 VCM66_1459 Vibrio cholerae M66-2 hypothetical protein YP_002810226.1 1578459 R 579112 CDS YP_002810227.1 227081676 7772737 complement(1579051..1579527) 1 NC_012578.1 hypothetical protein 1579527 7772737 VCM66_1460 Vibrio cholerae M66-2 hypothetical protein YP_002810227.1 1579051 R 579112 CDS YP_002810228.1 227081677 7772738 1579572..1580585 1 NC_012578.1 formate dehydrogenase accessory protein 1580585 fdhD 7772738 fdhD Vibrio cholerae M66-2 formate dehydrogenase accessory protein YP_002810228.1 1579572 D 579112 CDS YP_002810229.1 227081678 7772739 complement(1580692..1582284) 1 NC_012578.1 ABC transporter ATP-binding protein 1582284 7772739 VCM66_1462 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810229.1 1580692 R 579112 CDS YP_002810230.1 227081679 7772740 complement(1582496..1584529) 1 NC_012578.1 sensor histidine kinase 1584529 7772740 VCM66_1463 Vibrio cholerae M66-2 sensor histidine kinase YP_002810230.1 1582496 R 579112 CDS YP_002810231.1 227081680 7772741 complement(1584519..1585973) 1 NC_012578.1 sigma-54 dependent response regulator 1585973 7772741 VCM66_1464 Vibrio cholerae M66-2 sigma-54 dependent response regulator YP_002810231.1 1584519 R 579112 CDS YP_002810232.1 227081681 7772742 1586265..1587092 1 NC_012578.1 hypothetical protein 1587092 7772742 VCM66_1465 Vibrio cholerae M66-2 hypothetical protein YP_002810232.1 1586265 D 579112 CDS YP_002810233.1 227081682 7772743 1587099..1587797 1 NC_012578.1 ABC transporter permease 1587797 7772743 VCM66_1466 Vibrio cholerae M66-2 ABC transporter permease YP_002810233.1 1587099 D 579112 CDS YP_002810234.1 227081683 7772744 1587806..1588528 1 NC_012578.1 ABC transporter ATP-binding protein 1588528 7772744 VCM66_1467 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810234.1 1587806 D 579112 CDS YP_002810235.1 227081684 7772745 1588482..1589093 1 NC_012578.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 1589093 mobA 7772745 mobA Vibrio cholerae M66-2 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002810235.1 1588482 D 579112 CDS YP_002810236.1 227081685 7772746 1589090..1590910 1 NC_012578.1 putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA 1590910 moeA-1 7772746 moeA-1 Vibrio cholerae M66-2 putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA YP_002810236.1 1589090 D 579112 CDS YP_002810237.1 227081686 7773959 complement(1591789..1591950) 1 NC_012578.1 hypothetical protein 1591950 7773959 VCM66_1472 Vibrio cholerae M66-2 hypothetical protein YP_002810237.1 1591789 R 579112 CDS YP_002810238.1 227081687 7772748 1591994..1592269 1 NC_012578.1 hypothetical protein 1592269 7772748 VCM66_1473 Vibrio cholerae M66-2 hypothetical protein YP_002810238.1 1591994 D 579112 CDS YP_002810239.1 227081688 7772749 complement(1592476..1593384) 1 NC_012578.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1593384 7772749 VCM66_1474 Vibrio cholerae M66-2 N-acetyl-D-glucosamine kinase YP_002810239.1 1592476 R 579112 CDS YP_002810240.1 227081689 7772750 complement(1593547..1594284) 1 NC_012578.1 hypothetical protein 1594284 7772750 VCM66_1475 Vibrio cholerae M66-2 hypothetical protein YP_002810240.1 1593547 R 579112 CDS YP_002810241.1 227081690 7772751 1594261..1595175 1 NC_012578.1 hypothetical protein 1595175 7772751 VCM66_1476 Vibrio cholerae M66-2 hypothetical protein YP_002810241.1 1594261 D 579112 CDS YP_002810242.1 227081691 7772752 complement(1595177..1597198) 1 NC_012578.1 methyl-accepting chemotaxis protein 1597198 7772752 VCM66_1477 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810242.1 1595177 R 579112 CDS YP_002810243.1 227081692 7772753 1597287..1597787 1 NC_012578.1 lipoprotein NlpC 1597787 nlpC 7772753 nlpC Vibrio cholerae M66-2 lipoprotein NlpC YP_002810243.1 1597287 D 579112 CDS YP_002810244.1 227081693 7772754 complement(1597797..1598228) 1 NC_012578.1 hypothetical protein 1598228 7772754 VCM66_1479 Vibrio cholerae M66-2 hypothetical protein YP_002810244.1 1597797 R 579112 CDS YP_002810245.1 227081694 7772755 1598661..1599527 1 NC_012578.1 hypothetical protein 1599527 7772755 VCM66_1480 Vibrio cholerae M66-2 hypothetical protein YP_002810245.1 1598661 D 579112 CDS YP_002810246.1 227081695 7772756 1600131..1601516 1 NC_012578.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1601516 7772756 VCM66_1481 Vibrio cholerae M66-2 multidrug efflux protein YP_002810246.1 1600131 D 579112 CDS YP_002810247.1 227081696 7772757 1601720..1602703 1 NC_012578.1 hypothetical protein 1602703 7772757 VCM66_1482 Vibrio cholerae M66-2 hypothetical protein YP_002810247.1 1601720 D 579112 CDS YP_002810248.1 227081697 7772758 complement(1602710..1603558) 1 NC_012578.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 1603558 ligA-2 7772758 ligA-2 Vibrio cholerae M66-2 DNA ligase YP_002810248.1 1602710 R 579112 CDS YP_002810249.1 227081698 7772759 complement(1603865..1605043) 1 NC_012578.1 hypothetical protein 1605043 7772759 VCM66_1484 Vibrio cholerae M66-2 hypothetical protein YP_002810249.1 1603865 R 579112 CDS YP_002810250.1 227081699 7772760 complement(1605040..1605660) 1 NC_012578.1 tonB2 protein 1605660 tonB2 7772760 tonB2 Vibrio cholerae M66-2 tonB2 protein YP_002810250.1 1605040 R 579112 CDS YP_002810251.1 227081700 7772761 complement(1605660..1606064) 1 NC_012578.1 TonB system transport protein ExbD2 1606064 exbD2 7772761 exbD2 Vibrio cholerae M66-2 TonB system transport protein ExbD2 YP_002810251.1 1605660 R 579112 CDS YP_002810252.1 227081701 7772762 complement(1606061..1606603) 1 NC_012578.1 TonB system transport protein ExbB2 1606603 exbB2 7772762 exbB2 Vibrio cholerae M66-2 TonB system transport protein ExbB2 YP_002810252.1 1606061 R 579112 CDS YP_002810253.1 227081702 7772763 complement(1606610..1607983) 1 NC_012578.1 biopolymer transport protein 1607983 7772763 VCM66_1488 Vibrio cholerae M66-2 biopolymer transport protein YP_002810253.1 1606610 R 579112 CDS YP_002810254.1 227081703 7772764 complement(1607983..1608741) 1 NC_012578.1 hypothetical protein 1608741 7772764 VCM66_1489 Vibrio cholerae M66-2 hypothetical protein YP_002810254.1 1607983 R 579112 CDS YP_002810255.1 227081704 7772765 1609060..1610364 1 NC_012578.1 glycerol-3-phosphate ABC transporter substrate-binding protein 1610364 ugpB 7772765 ugpB Vibrio cholerae M66-2 glycerol-3-phosphate ABC transporter substrate-binding protein YP_002810255.1 1609060 D 579112 CDS YP_002810256.1 227081705 7772766 1610440..1611321 1 NC_012578.1 glycerol-3-phosphate ABC transporter permease 1611321 ugpA 7772766 ugpA Vibrio cholerae M66-2 glycerol-3-phosphate ABC transporter permease YP_002810256.1 1610440 D 579112 CDS YP_002810257.1 227081706 7772767 1611331..1612173 1 NC_012578.1 glycerol-3-phosphate ABC transporter permease 1612173 ugpE 7772767 ugpE Vibrio cholerae M66-2 glycerol-3-phosphate ABC transporter permease YP_002810257.1 1611331 D 579112 CDS YP_002810258.1 227081707 7772768 1612163..1613344 1 NC_012578.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 1613344 ugpC 7772768 ugpC Vibrio cholerae M66-2 glycerol-3-phosphate transporter ATP-binding subunit YP_002810258.1 1612163 D 579112 CDS YP_002810259.1 227081708 7772769 1613369..1614130 1 NC_012578.1 glycerol-3-phosphate regulon repressor 1614130 glpR 7772769 glpR Vibrio cholerae M66-2 glycerol-3-phosphate regulon repressor YP_002810259.1 1613369 D 579112 CDS YP_002810260.1 227081709 7772770 1614158..1614871 1 NC_012578.1 putative glycerophosphoryl diester phosphodiesterase 1614871 7772770 VCM66_1495 Vibrio cholerae M66-2 putative glycerophosphoryl diester phosphodiesterase YP_002810260.1 1614158 D 579112 CDS YP_002810261.1 227081710 7772771 complement(1614947..1615459) 1 NC_012578.1 hypothetical protein 1615459 7772771 VCM66_1496 Vibrio cholerae M66-2 hypothetical protein YP_002810261.1 1614947 R 579112 CDS YP_002810262.1 227081711 7772772 complement(1615428..1615790) 1 NC_012578.1 hypothetical protein 1615790 7772772 VCM66_1497 Vibrio cholerae M66-2 hypothetical protein YP_002810262.1 1615428 R 579112 CDS YP_002810263.1 227081712 7772773 complement(1615925..1616959) 1 NC_012578.1 LacI family transcriptional regulator 1616959 7772773 VCM66_1498 Vibrio cholerae M66-2 LacI family transcriptional regulator YP_002810263.1 1615925 R 579112 CDS YP_002810264.1 227081713 7772774 complement(1616995..1618431) 1 NC_012578.1 6-phospho-beta-glucosidase 1618431 bglA 7772774 bglA Vibrio cholerae M66-2 6-phospho-beta-glucosidase YP_002810264.1 1616995 R 579112 CDS YP_002810265.1 227081714 7772775 1618722..1618823 1 NC_012578.1 hypothetical protein 1618823 7772775 VCM66_1500 Vibrio cholerae M66-2 hypothetical protein YP_002810265.1 1618722 D 579112 CDS YP_002810266.1 227081715 7772776 1618844..1621018 1 NC_012578.1 catalase/peroxidase 1621018 perA 7772776 perA Vibrio cholerae M66-2 catalase/peroxidase YP_002810266.1 1618844 D 579112 CDS YP_002810267.1 227081716 7772777 complement(1621083..1622012) 1 NC_012578.1 LysR family transcriptional regulator 1622012 7772777 VCM66_1502 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810267.1 1621083 R 579112 CDS YP_002810268.1 227081717 7772778 1622076..1623248 1 NC_012578.1 beta-lactamase-like protein 1623248 7772778 VCM66_1503 Vibrio cholerae M66-2 beta-lactamase-like protein YP_002810268.1 1622076 D 579112 CDS YP_002810269.1 227081718 7772779 1623398..1624558 1 NC_012578.1 hypothetical protein 1624558 7772779 VCM66_1504 Vibrio cholerae M66-2 hypothetical protein YP_002810269.1 1623398 D 579112 CDS YP_002810270.1 227081719 7772780 1624551..1625810 1 NC_012578.1 putative outer membrane protein TolC 1625810 7772780 VCM66_1505 Vibrio cholerae M66-2 putative outer membrane protein TolC YP_002810270.1 1624551 D 579112 CDS YP_002810271.1 227081720 7772781 1625810..1627024 1 NC_012578.1 hypothetical protein 1627024 7772781 VCM66_1506 Vibrio cholerae M66-2 hypothetical protein YP_002810271.1 1625810 D 579112 CDS YP_002810272.1 227081721 7772782 1627028..1628305 1 NC_012578.1 hypothetical protein 1628305 7772782 VCM66_1507 Vibrio cholerae M66-2 hypothetical protein YP_002810272.1 1627028 D 579112 CDS YP_002810273.1 227081722 7772783 1628305..1629006 1 NC_012578.1 ABC transporter ATP-binding protein 1629006 7772783 VCM66_1508 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810273.1 1628305 D 579112 CDS YP_002810274.1 227081723 7772784 1628972..1629073 1 NC_012578.1 hypothetical protein 1629073 7772784 VCM66_1509 Vibrio cholerae M66-2 hypothetical protein YP_002810274.1 1628972 D 579112 CDS YP_002810275.1 227081724 7772785 complement(1629080..1630072) 1 NC_012578.1 quinol oxidase subunit II 1630072 qxtB 7772785 qxtB Vibrio cholerae M66-2 quinol oxidase subunit II YP_002810275.1 1629080 R 579112 CDS YP_002810276.1 227081725 7772786 complement(1630069..1631406) 1 NC_012578.1 quinol oxidase subunit I 1631406 qxtA 7772786 qxtA Vibrio cholerae M66-2 quinol oxidase subunit I YP_002810276.1 1630069 R 579112 CDS YP_002810277.1 227081726 7772787 1631929..1632309 1 NC_012578.1 hypothetical protein 1632309 7772787 VCM66_1512 Vibrio cholerae M66-2 hypothetical protein YP_002810277.1 1631929 D 579112 CDS YP_002810278.1 227081727 7772788 1632325..1633710 1 NC_012578.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1633710 fumC 7772788 fumC Vibrio cholerae M66-2 fumarate hydratase YP_002810278.1 1632325 D 579112 CDS YP_002810279.1 227081728 7772789 complement(1633855..1634238) 1 NC_012578.1 hypothetical protein 1634238 7772789 VCM66_1514 Vibrio cholerae M66-2 hypothetical protein YP_002810279.1 1633855 R 579112 CDS YP_002810280.1 227081729 7772790 complement(1634283..1634741) 1 NC_012578.1 hypothetical protein 1634741 7772790 VCM66_1515 Vibrio cholerae M66-2 hypothetical protein YP_002810280.1 1634283 R 579112 CDS YP_002810281.1 227081730 7772791 complement(1634771..1635088) 1 NC_012578.1 hypothetical protein 1635088 7772791 VCM66_1516 Vibrio cholerae M66-2 hypothetical protein YP_002810281.1 1634771 R 579112 CDS YP_002810282.1 227081731 7772792 complement(1635244..1636065) 1 NC_012578.1 hypothetical protein 1636065 7772792 VCM66_1517 Vibrio cholerae M66-2 hypothetical protein YP_002810282.1 1635244 R 579112 CDS YP_002810283.1 227081732 7772793 complement(1636287..1637957) 1 NC_012578.1 enterobactin synthetase component F-like protein 1637957 7772793 VCM66_1519 Vibrio cholerae M66-2 enterobactin synthetase component F-like protein YP_002810283.1 1636287 R 579112 CDS YP_002810284.1 227081733 7772794 complement(1638021..1638932) 1 NC_012578.1 LysR family transcriptional regulator 1638932 7772794 VCM66_1520 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810284.1 1638021 R 579112 CDS YP_002810285.1 227081734 7772795 1639012..1640562 1 NC_012578.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1640562 7772795 VCM66_1521 Vibrio cholerae M66-2 NADH dehydrogenase subunit L YP_002810285.1 1639012 D 579112 CDS YP_002810286.1 227081735 7772796 1640487..1643075 1 NC_012578.1 hypothetical protein 1643075 7772796 VCM66_1522 Vibrio cholerae M66-2 hypothetical protein YP_002810286.1 1640487 D 579112 CDS YP_002810287.1 227081736 7772797 complement(1643120..1643635) 1 NC_012578.1 superoxide dismutase, Cu-Zn 1643635 sodC 7772797 sodC Vibrio cholerae M66-2 superoxide dismutase, Cu-Zn YP_002810287.1 1643120 R 579112 CDS YP_002810288.1 227081737 7772798 complement(1643675..1644241) 1 NC_012578.1 ankB protein 1644241 ankB 7772798 ankB Vibrio cholerae M66-2 ankB protein YP_002810288.1 1643675 R 579112 CDS YP_002810289.1 227081738 7772799 complement(1644305..1646008) 1 NC_012578.1 catalase 1646008 katB 7772799 katB Vibrio cholerae M66-2 catalase YP_002810289.1 1644305 R 579112 CDS YP_002810290.1 227081739 7772800 complement(1646181..1646282) 1 NC_012578.1 hypothetical protein 1646282 7772800 VCM66_1526 Vibrio cholerae M66-2 hypothetical protein YP_002810290.1 1646181 R 579112 CDS YP_002810291.1 227081740 7772801 1646262..1646702 1 NC_012578.1 hypothetical protein 1646702 7772801 VCM66_1527 Vibrio cholerae M66-2 hypothetical protein YP_002810291.1 1646262 D 579112 CDS YP_002810292.1 227081741 7772802 complement(1646891..1647769) 1 NC_012578.1 LysR family transcriptional regulator 1647769 alsR 7772802 alsR Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810292.1 1646891 R 579112 CDS YP_002810293.1 227081742 7772803 1647878..1648663 1 NC_012578.1 alpha-acetolactate decarboxylase 1648663 aldC 7772803 aldC Vibrio cholerae M66-2 alpha-acetolactate decarboxylase YP_002810293.1 1647878 D 579112 CDS YP_002810294.1 227081743 7772804 1648802..1650505 1 NC_012578.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1650505 alsS 7772804 alsS Vibrio cholerae M66-2 acetolactate synthase YP_002810294.1 1648802 D 579112 CDS YP_002810295.1 227081744 7772805 1650502..1651260 1 NC_012578.1 oxidoreductase, short-chain dehydrogenase/reductase family 1651260 alsO 7772805 alsO Vibrio cholerae M66-2 oxidoreductase, short-chain dehydrogenase/reductase family YP_002810295.1 1650502 D 579112 CDS YP_002810296.1 227081745 7772806 1651498..1652352 1 NC_012578.1 EAL family protein 1652352 7772806 VCM66_1532 Vibrio cholerae M66-2 EAL family protein YP_002810296.1 1651498 D 579112 CDS YP_002810297.1 227081746 7772807 1652435..1653724 1 NC_012578.1 GGDEF family protein 1653724 7772807 VCM66_1533 Vibrio cholerae M66-2 GGDEF family protein YP_002810297.1 1652435 D 579112 CDS YP_002810298.1 227081747 7772808 complement(1653742..1654794) 1 NC_012578.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 1654794 galM 7772808 galM Vibrio cholerae M66-2 aldose 1-epimerase YP_002810298.1 1653742 R 579112 CDS YP_002810299.1 227081748 7772809 complement(1654803..1656020) 1 NC_012578.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1656020 galK 7772809 galK Vibrio cholerae M66-2 galactokinase YP_002810299.1 1654803 R 579112 CDS YP_002810300.1 227081749 7772810 complement(1656029..1657147) 1 NC_012578.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 1657147 galT 7772810 galT Vibrio cholerae M66-2 galactose-1-phosphate uridylyltransferase YP_002810300.1 1656029 R 579112 CDS YP_002810301.1 227081750 7772811 complement(1657537..1658970) 1 NC_012578.1 putative multidrug transporter 1658970 7772811 VCM66_1537 Vibrio cholerae M66-2 putative multidrug transporter YP_002810301.1 1657537 R 579112 CDS YP_002810302.1 227081751 7772812 1659119..1659943 1 NC_012578.1 ABC transporter substrate-binding protein 1659943 7772812 VCM66_1538 Vibrio cholerae M66-2 ABC transporter substrate-binding protein YP_002810302.1 1659119 D 579112 CDS YP_002810303.1 227081752 7774081 1660559..1661620 1 NC_012578.1 GGDEF family protein 1661620 7774081 VCM66_1539 Vibrio cholerae M66-2 GGDEF family protein YP_002810303.1 1660559 D 579112 CDS YP_002810304.1 227081753 7772814 complement(1661623..1662312) 1 NC_012578.1 hypothetical protein 1662312 7772814 VCM66_1540 Vibrio cholerae M66-2 hypothetical protein YP_002810304.1 1661623 R 579112 CDS YP_002810305.1 227081754 7772815 complement(1662427..1663230) 1 NC_012578.1 hypothetical protein 1663230 7772815 VCM66_1541 Vibrio cholerae M66-2 hypothetical protein YP_002810305.1 1662427 R 579112 CDS YP_002810306.1 227081755 7772816 complement(1663362..1664348) 1 NC_012578.1 chemotaxis protein CheV 1664348 cheV-1 7772816 cheV-1 Vibrio cholerae M66-2 chemotaxis protein CheV YP_002810306.1 1663362 R 579112 CDS YP_002810307.1 227081756 7772817 complement(1664367..1665143) 1 NC_012578.1 hypothetical protein 1665143 7772817 VCM66_1543 Vibrio cholerae M66-2 hypothetical protein YP_002810307.1 1664367 R 579112 CDS YP_002810308.1 227081757 7772818 complement(1665209..1665895) 1 NC_012578.1 response regulator 1665895 7772818 VCM66_1544 Vibrio cholerae M66-2 response regulator YP_002810308.1 1665209 R 579112 CDS YP_002810309.1 227081758 7772819 complement(1665895..1667511) 1 NC_012578.1 putative sensor kinase citA 1667511 7772819 VCM66_1545 Vibrio cholerae M66-2 putative sensor kinase citA YP_002810309.1 1665895 R 579112 CDS YP_002810310.1 227081759 7772820 1668241..1669671 1 NC_012578.1 hypothetical protein 1669671 7772820 VCM66_1546 Vibrio cholerae M66-2 hypothetical protein YP_002810310.1 1668241 D 579112 CDS YP_002810311.1 227081760 7772821 1669683..1670657 1 NC_012578.1 hypothetical protein 1670657 7772821 VCM66_1547 Vibrio cholerae M66-2 hypothetical protein YP_002810311.1 1669683 D 579112 CDS YP_002810312.1 227081761 7772822 1670661..1671824 1 NC_012578.1 hypothetical protein 1671824 7772822 VCM66_1548 Vibrio cholerae M66-2 hypothetical protein YP_002810312.1 1670661 D 579112 CDS YP_002810313.1 227081762 7772823 1671743..1672969 1 NC_012578.1 hypothetical protein 1672969 7772823 VCM66_1549 Vibrio cholerae M66-2 hypothetical protein YP_002810313.1 1671743 D 579112 CDS YP_002810314.1 227081763 7772824 complement(1672973..1673422) 1 NC_012578.1 NEDD4-binding protein 1673422 7772824 VCM66_1550 Vibrio cholerae M66-2 NEDD4-binding protein YP_002810314.1 1672973 R 579112 CDS YP_002810315.1 227081764 7772825 1673470..1674429 1 NC_012578.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1674429 metA 7772825 metA Vibrio cholerae M66-2 homoserine O-succinyltransferase YP_002810315.1 1673470 D 579112 CDS YP_002810316.1 227081765 7772826 1674638..1675351 1 NC_012578.1 putative fimbrial biogenesis and twitching motility protein 1675351 7772826 VCM66_1552 Vibrio cholerae M66-2 putative fimbrial biogenesis and twitching motility protein YP_002810316.1 1674638 D 579112 CDS YP_002810317.1 227081766 7772827 complement(1675355..1675579) 1 NC_012578.1 hypothetical protein 1675579 7772827 VCM66_1553 Vibrio cholerae M66-2 hypothetical protein YP_002810317.1 1675355 R 579112 CDS YP_002810318.1 227081767 7772828 complement(1675778..1676866) 1 NC_012578.1 putative SAM-dependent methyltransferase 1676866 7772828 VCM66_1554 Vibrio cholerae M66-2 putative SAM-dependent methyltransferase YP_002810318.1 1675778 R 579112 CDS YP_002810319.1 227081768 7772829 complement(1676863..1677375) 1 NC_012578.1 hypothetical protein 1677375 7772829 VCM66_1555 Vibrio cholerae M66-2 hypothetical protein YP_002810319.1 1676863 R 579112 CDS YP_002810320.1 227081769 7772830 1677543..1677776 1 NC_012578.1 putative glutaredoxin 1677776 7772830 VCM66_1556 Vibrio cholerae M66-2 putative glutaredoxin YP_002810320.1 1677543 D 579112 CDS YP_002810321.1 227081770 7772831 complement(1677807..1678697) 1 NC_012578.1 LysR family transcriptional regulator 1678697 7772831 VCM66_1557 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810321.1 1677807 R 579112 CDS YP_002810322.1 227081771 7772832 1678782..1679999 1 NC_012578.1 putative multidrug resistance protein 1679999 7772832 VCM66_1558 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002810322.1 1678782 D 579112 CDS YP_002810323.1 227081772 7772833 1680056..1680604 1 NC_012578.1 hypothetical protein 1680604 7772833 VCM66_1559 Vibrio cholerae M66-2 hypothetical protein YP_002810323.1 1680056 D 579112 CDS YP_002810324.1 227081773 7772834 complement(1680714..1688495) 1 NC_012578.1 RTX toxin 1688495 7772834 VCM66_1560 Vibrio cholerae M66-2 RTX toxin YP_002810324.1 1680714 R 579112 CDS YP_002810325.1 227081774 7772835 1688892..1690229 1 NC_012578.1 agglutination protein 1690229 7772835 VCM66_1561 Vibrio cholerae M66-2 agglutination protein YP_002810325.1 1688892 D 579112 CDS YP_002810326.1 227081775 7772836 1690231..1690869 1 NC_012578.1 putative outer membrane protein 1690869 7772836 VCM66_1562 Vibrio cholerae M66-2 putative outer membrane protein YP_002810326.1 1690231 D 579112 CDS YP_002810327.1 227081776 7772837 complement(1691005..1692168) 1 NC_012578.1 carboxynorspermidine decarboxylase 1692168 nspC 7772837 nspC Vibrio cholerae M66-2 carboxynorspermidine decarboxylase YP_002810327.1 1691005 R 579112 CDS YP_002810328.1 227081777 7772838 complement(1692404..1693648) 1 NC_012578.1 hypothetical protein 1693648 7772838 VCM66_1564 Vibrio cholerae M66-2 hypothetical protein YP_002810328.1 1692404 R 579112 CDS YP_002810329.1 227081778 7772839 complement(1693662..1696547) 1 NC_012578.1 aminotransferase, class III/decarboxylase, group II 1696547 7772839 VCM66_1565 Vibrio cholerae M66-2 aminotransferase, class III/decarboxylase, group II YP_002810329.1 1693662 R 579112 CDS YP_002810330.1 227081779 7772840 complement(1697145..1698293) 1 NC_012578.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1698293 nhaA 7772840 nhaA Vibrio cholerae M66-2 pH-dependent sodium/proton antiporter YP_002810330.1 1697145 R 579112 CDS YP_002810331.1 227081780 7772841 complement(1698572..1699690) 1 NC_012578.1 hypothetical protein 1699690 7772841 VCM66_1567 Vibrio cholerae M66-2 hypothetical protein YP_002810331.1 1698572 R 579112 CDS YP_002810332.1 227081781 7772842 complement(1699691..1702201) 1 NC_012578.1 hypothetical protein 1702201 7772842 VCM66_1568 Vibrio cholerae M66-2 hypothetical protein YP_002810332.1 1699691 R 579112 CDS YP_002810333.1 227081782 7772843 complement(1702125..1702808) 1 NC_012578.1 ABC transporter ATP-binding protein 1702808 7772843 VCM66_1569 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810333.1 1702125 R 579112 CDS YP_002810334.1 227081783 7772844 complement(1702922..1704298) 1 NC_012578.1 hypothetical protein 1704298 7772844 VCM66_1570 Vibrio cholerae M66-2 hypothetical protein YP_002810334.1 1702922 R 579112 CDS YP_002810335.1 227081784 7772845 1704426..1705862 1 NC_012578.1 hypothetical protein 1705862 7772845 VCM66_1571 Vibrio cholerae M66-2 hypothetical protein YP_002810335.1 1704426 D 579112 CDS YP_002810336.1 227081785 7772846 complement(1705929..1706666) 1 NC_012578.1 hypothetical protein 1706666 7772846 VCM66_1572 Vibrio cholerae M66-2 hypothetical protein YP_002810336.1 1705929 R 579112 CDS YP_002810337.1 227081786 7772847 complement(1706588..1707793) 1 NC_012578.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 1707793 7772847 VCM66_1573 Vibrio cholerae M66-2 bicyclomycin/multidrug efflux system YP_002810337.1 1706588 R 579112 CDS YP_002810338.1 227081787 7772848 complement(1708112..1708807) 1 NC_012578.1 ribosomal small subunit pseudouridine synthase A 1708807 7772848 VCM66_1574 Vibrio cholerae M66-2 ribosomal small subunit pseudouridine synthase A YP_002810338.1 1708112 R 579112 CDS YP_002810339.1 227081788 7772849 1708752..1710725 1 NC_012578.1 helicase-like protein 1710725 7772849 VCM66_1575 Vibrio cholerae M66-2 helicase-like protein YP_002810339.1 1708752 D 579112 CDS YP_002810340.1 227081789 7772850 1710990..1711397 1 NC_012578.1 hypothetical protein 1711397 7772850 VCM66_1576 Vibrio cholerae M66-2 hypothetical protein YP_002810340.1 1710990 D 579112 CDS YP_002810341.1 227081790 7772851 1711409..1712068 1 NC_012578.1 DNA-binding response regulator 1712068 7772851 VCM66_1577 Vibrio cholerae M66-2 DNA-binding response regulator YP_002810341.1 1711409 D 579112 CDS YP_002810342.1 227081791 7772852 1712043..1713431 1 NC_012578.1 sensor histidine kinase 1713431 7772852 VCM66_1578 Vibrio cholerae M66-2 sensor histidine kinase YP_002810342.1 1712043 D 579112 CDS YP_002810343.1 227081792 7772853 1713589..1713867 1 NC_012578.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1713867 rplY 7772853 rplY Vibrio cholerae M66-2 50S ribosomal protein L25 YP_002810343.1 1713589 D 579112 CDS YP_002810344.1 227081793 7772854 complement(1714017..1714790) 1 NC_012578.1 EAL family protein 1714790 7772854 VCM66_1580 Vibrio cholerae M66-2 EAL family protein YP_002810344.1 1714017 R 579112 CDS YP_002810345.1 227081794 7772855 complement(1714882..1715283) 1 NC_012578.1 hypothetical protein 1715283 7772855 VCM66_1581 Vibrio cholerae M66-2 hypothetical protein YP_002810345.1 1714882 R 579112 CDS YP_002810346.1 227081795 7772856 1715474..1717264 1 NC_012578.1 methyl-accepting chemotaxis protein 1717264 7772856 VCM66_1582 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810346.1 1715474 D 579112 CDS YP_002810347.1 227081796 7772857 1717596..1718840 1 NC_012578.1 hypothetical protein 1718840 7772857 VCM66_1583 Vibrio cholerae M66-2 hypothetical protein YP_002810347.1 1717596 D 579112 CDS YP_002810348.1 227081797 7772858 complement(1718957..1719568) 1 NC_012578.1 hypothetical protein 1719568 7772858 VCM66_1584 Vibrio cholerae M66-2 hypothetical protein YP_002810348.1 1718957 R 579112 CDS YP_002810349.1 227081798 7772859 complement(1719736..1719939) 1 NC_012578.1 hypothetical protein 1719939 7772859 VCM66_1585 Vibrio cholerae M66-2 hypothetical protein YP_002810349.1 1719736 R 579112 CDS YP_002810350.1 227081799 7772860 1719980..1721893 1 NC_012578.1 hypothetical protein 1721893 7772860 VCM66_1586 Vibrio cholerae M66-2 hypothetical protein YP_002810350.1 1719980 D 579112 CDS YP_002810351.1 227081800 7772861 1721857..1721952 1 NC_012578.1 hypothetical protein 1721952 7772861 VCM66_1587 Vibrio cholerae M66-2 hypothetical protein YP_002810351.1 1721857 D 579112 CDS YP_002810352.1 227081801 7772862 complement(1721974..1723620) 1 NC_012578.1 putative trypsin 1723620 7772862 VCM66_1588 Vibrio cholerae M66-2 putative trypsin YP_002810352.1 1721974 R 579112 CDS YP_002810353.1 227081802 7772863 1723948..1726404 1 NC_012578.1 collagenase 1726404 vcc 7772863 vcc Vibrio cholerae M66-2 collagenase YP_002810353.1 1723948 D 579112 CDS YP_002810354.1 227081803 7772864 complement(1726438..1728099) 1 NC_012578.1 response regulator VieB 1728099 vieB 7772864 vieB Vibrio cholerae M66-2 response regulator VieB YP_002810354.1 1726438 R 579112 CDS YP_002810355.1 227081804 7772865 complement(1728111..1729865) 1 NC_012578.1 response regulator VieA 1729865 vieA 7772865 vieA Vibrio cholerae M66-2 response regulator VieA YP_002810355.1 1728111 R 579112 CDS YP_002810356.1 227081805 7772866 complement(1729870..1733310) 1 NC_012578.1 sensory box sensor histidine kinase/response regulator VieS 1733310 vieS 7772866 vieS Vibrio cholerae M66-2 sensory box sensor histidine kinase/response regulator VieS YP_002810356.1 1729870 R 579112 CDS YP_002810357.1 227081806 7772867 1734101..1735456 1 NC_012578.1 magnesium transporter 1735456 mgtE-1 7772867 mgtE-1 Vibrio cholerae M66-2 magnesium transporter YP_002810357.1 1734101 D 579112 CDS YP_002810358.1 227081807 7772868 complement(1735539..1736402) 1 NC_012578.1 hypothetical protein 1736402 7772868 VCM66_1595 Vibrio cholerae M66-2 hypothetical protein YP_002810358.1 1735539 R 579112 CDS YP_002810359.1 227081808 7772869 1736738..1737991 1 NC_012578.1 serine transporter 1737991 sdaC-2 7772869 sdaC-2 Vibrio cholerae M66-2 serine transporter YP_002810359.1 1736738 D 579112 CDS YP_002810360.1 227081809 7772870 1738160..1739107 1 NC_012578.1 hypothetical protein 1739107 7772870 VCM66_1598 Vibrio cholerae M66-2 hypothetical protein YP_002810360.1 1738160 D 579112 CDS YP_002810361.1 227081810 7772871 1739117..1740043 1 NC_012578.1 ABC transporter ATP-binding protein 1740043 7772871 VCM66_1599 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810361.1 1739117 D 579112 CDS YP_002810362.1 227081811 7772872 1740040..1741137 1 NC_012578.1 multidrug ABC transporter permease 1741137 7772872 VCM66_1600 Vibrio cholerae M66-2 multidrug ABC transporter permease YP_002810362.1 1740040 D 579112 CDS YP_002810363.1 227081812 7772873 1741296..1741517 1 NC_012578.1 hypothetical protein 1741517 7772873 VCM66_1601 Vibrio cholerae M66-2 hypothetical protein YP_002810363.1 1741296 D 579112 CDS YP_002810364.1 227081813 7772874 complement(1741523..1741789) 1 NC_012578.1 hypothetical protein 1741789 7772874 VCM66_1602 Vibrio cholerae M66-2 hypothetical protein YP_002810364.1 1741523 R 579112 CDS YP_002810365.1 227081814 7772875 1741936..1742379 1 NC_012578.1 heat shock protein HslJ 1742379 hslJ 7772875 hslJ Vibrio cholerae M66-2 heat shock protein HslJ YP_002810365.1 1741936 D 579112 CDS YP_002810366.1 227081815 7772876 1742587..1743735 1 NC_012578.1 putative ABC transporter solute-binding protein 1743735 7772876 VCM66_1604 Vibrio cholerae M66-2 putative ABC transporter solute-binding protein YP_002810366.1 1742587 D 579112 CDS YP_002810367.1 227081816 7772877 1743749..1745449 1 NC_012578.1 ABC transporter permease 1745449 7772877 VCM66_1605 Vibrio cholerae M66-2 ABC transporter permease YP_002810367.1 1743749 D 579112 CDS YP_002810368.1 227081817 7772878 1745415..1746077 1 NC_012578.1 ABC transporter ATP-binding protein 1746077 7772878 VCM66_1606 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810368.1 1745415 D 579112 CDS YP_002810369.1 227081818 7772879 1746070..1746690 1 NC_012578.1 putative Inner membrane protein 1746690 7772879 VCM66_1607 Vibrio cholerae M66-2 putative Inner membrane protein YP_002810369.1 1746070 D 579112 CDS YP_002810370.1 227081819 7772880 complement(1746749..1747456) 1 NC_012578.1 pseudouridine synthase Rlu family protein 1747456 7772880 VCM66_1608 Vibrio cholerae M66-2 pseudouridine synthase Rlu family protein YP_002810370.1 1746749 R 579112 CDS YP_002810371.1 227081820 7772881 complement(1747555..1748901) 1 NC_012578.1 putative sodium-dependent transporter 1748901 7772881 VCM66_1609 Vibrio cholerae M66-2 putative sodium-dependent transporter YP_002810371.1 1747555 R 579112 CDS YP_002810372.1 227081821 7772882 1749457..1750911 1 NC_012578.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1750911 cls 7772882 cls Vibrio cholerae M66-2 cardiolipin synthetase YP_002810372.1 1749457 D 579112 CDS YP_002810373.1 227081822 7772883 1750992..1752182 1 NC_012578.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 1752182 metC 7772883 metC Vibrio cholerae M66-2 cystathionine beta-lyase YP_002810373.1 1750992 D 579112 CDS YP_002810374.1 227081823 7772884 complement(1752269..1752850) 1 NC_012578.1 DNA-3-methyladenine glycosidase I 1752850 tag 7772884 tag Vibrio cholerae M66-2 DNA-3-methyladenine glycosidase I YP_002810374.1 1752269 R 579112 CDS YP_002810375.1 227081824 7772885 complement(1752937..1756050) 1 NC_012578.1 transporter, AcrB/D/F family 1756050 7772885 VCM66_1613 Vibrio cholerae M66-2 transporter, AcrB/D/F family YP_002810375.1 1752937 R 579112 CDS YP_002810376.1 227081825 7772886 complement(1756028..1757137) 1 NC_012578.1 putative periplasmic linker protein 1757137 7772886 VCM66_1614 Vibrio cholerae M66-2 putative periplasmic linker protein YP_002810376.1 1756028 R 579112 CDS YP_002810377.1 227081826 7772887 complement(1757109..1758140) 1 NC_012578.1 putative multidrug resistance protein 1758140 7772887 VCM66_1615 Vibrio cholerae M66-2 putative multidrug resistance protein YP_002810377.1 1757109 R 579112 CDS YP_002810378.1 227081827 7772888 complement(1758312..1758728) 1 NC_012578.1 phage shock protein C 1758728 pspC 7772888 pspC Vibrio cholerae M66-2 phage shock protein C YP_002810378.1 1758312 R 579112 CDS YP_002810379.1 227081828 7772889 complement(1758694..1758927) 1 NC_012578.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1758927 pspB 7772889 pspB Vibrio cholerae M66-2 phage shock protein B YP_002810379.1 1758694 R 579112 CDS YP_002810380.1 227081829 7772890 complement(1758941..1759609) 1 NC_012578.1 phage shock protein A 1759609 pspA 7772890 pspA Vibrio cholerae M66-2 phage shock protein A YP_002810380.1 1758941 R 579112 CDS YP_002810381.1 227081830 7772891 1759819..1760835 1 NC_012578.1 psp operon transcriptional activator 1760835 pspF 7772891 pspF Vibrio cholerae M66-2 psp operon transcriptional activator YP_002810381.1 1759819 D 579112 CDS YP_002810382.1 227081831 7772892 1760949..1762571 1 NC_012578.1 peptide ABC transporter substrate-binding protein 1762571 sapA 7772892 sapA Vibrio cholerae M66-2 peptide ABC transporter substrate-binding protein YP_002810382.1 1760949 D 579112 CDS YP_002810383.1 227081832 7772893 1762571..1763533 1 NC_012578.1 peptide ABC transporter permease 1763533 sapB 7772893 sapB Vibrio cholerae M66-2 peptide ABC transporter permease YP_002810383.1 1762571 D 579112 CDS YP_002810384.1 227081833 7772894 1763520..1764407 1 NC_012578.1 peptide ABC transporter permease 1764407 sapC 7772894 sapC Vibrio cholerae M66-2 peptide ABC transporter permease YP_002810384.1 1763520 D 579112 CDS YP_002810385.1 227081834 7772895 1764407..1765402 1 NC_012578.1 peptide ABC transporter ATP-binding protein 1765402 sapD 7772895 sapD Vibrio cholerae M66-2 peptide ABC transporter ATP-binding protein YP_002810385.1 1764407 D 579112 CDS YP_002810386.1 227081835 7772896 1765399..1766187 1 NC_012578.1 peptide ABC transporter ATP-binding protein 1766187 sapF 7772896 sapF Vibrio cholerae M66-2 peptide ABC transporter ATP-binding protein YP_002810386.1 1765399 D 579112 CDS YP_002810387.1 227081836 7772897 1766188..1766958 1 NC_012578.1 hypothetical protein 1766958 7772897 VCM66_1625 Vibrio cholerae M66-2 hypothetical protein YP_002810387.1 1766188 D 579112 CDS YP_002810388.1 227081837 7772898 complement(1766995..1767549) 1 NC_012578.1 hypothetical protein 1767549 7772898 VCM66_1626 Vibrio cholerae M66-2 hypothetical protein YP_002810388.1 1766995 R 579112 CDS YP_002810389.1 227081838 7772899 complement(1767519..1768424) 1 NC_012578.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 1768424 7772899 VCM66_1627 Vibrio cholerae M66-2 putative manganese-dependent inorganic pyrophosphatase YP_002810389.1 1767519 R 579112 CDS YP_002810390.1 227081839 7772900 1768571..1769818 1 NC_012578.1 hypothetical protein 1769818 7772900 VCM66_1628 Vibrio cholerae M66-2 hypothetical protein YP_002810390.1 1768571 D 579112 CDS YP_002810391.1 227081840 7773960 1771674..1771772 1 NC_012578.1 hypothetical protein 1771772 7773960 VCM66_1631 Vibrio cholerae M66-2 hypothetical protein YP_002810391.1 1771674 D 579112 CDS YP_002810392.1 227081841 7772902 complement(1771825..1774287) 1 NC_012578.1 trimethylamine-N-oxide reductase 1774287 torA 7772902 torA Vibrio cholerae M66-2 trimethylamine-N-oxide reductase YP_002810392.1 1771825 R 579112 CDS YP_002810393.1 227081842 7772903 complement(1774311..1775495) 1 NC_012578.1 cytochrome c-type protein TorC 1775495 torC 7772903 torC Vibrio cholerae M66-2 cytochrome c-type protein TorC YP_002810393.1 1774311 R 579112 CDS YP_002810394.1 227081843 7772904 complement(1775542..1775760) 1 NC_012578.1 napE protein 1775760 napE 7772904 napE Vibrio cholerae M66-2 napE protein YP_002810394.1 1775542 R 579112 CDS YP_002810395.1 227081844 7772905 complement(1776404..1777246) 1 NC_012578.1 putative formate transporter 1777246 7772905 VCM66_1635 Vibrio cholerae M66-2 putative formate transporter YP_002810395.1 1776404 R 579112 CDS YP_002810396.1 227081845 7772906 1777451..1777831 1 NC_012578.1 DNA-binding protein inhibitor Id-2-like protein 1777831 7772906 VCM66_1636 Vibrio cholerae M66-2 DNA-binding protein inhibitor Id-2-like protein YP_002810396.1 1777451 D 579112 CDS YP_002810397.1 227081846 7772907 1777935..1778765 1 NC_012578.1 hypothetical protein 1778765 7772907 VCM66_1637 Vibrio cholerae M66-2 hypothetical protein YP_002810397.1 1777935 D 579112 CDS YP_002810398.1 227081847 7772908 1778758..1779405 1 NC_012578.1 hypothetical protein 1779405 7772908 VCM66_1638 Vibrio cholerae M66-2 hypothetical protein YP_002810398.1 1778758 D 579112 CDS YP_002810399.1 227081848 7772909 1779538..1779807 1 NC_012578.1 hypothetical protein 1779807 7772909 VCM66_1639 Vibrio cholerae M66-2 hypothetical protein YP_002810399.1 1779538 D 579112 CDS YP_002810400.1 227081849 7772910 1780040..1780585 1 NC_012578.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1780585 yciB 7772910 yciB Vibrio cholerae M66-2 intracellular septation protein A YP_002810400.1 1780040 D 579112 CDS YP_002810401.1 227081850 7772911 1780723..1781163 1 NC_012578.1 Acyl-CoA thioester hydrolase 1781163 7772911 VCM66_1641 Vibrio cholerae M66-2 Acyl-CoA thioester hydrolase YP_002810401.1 1780723 D 579112 CDS YP_002810402.1 227081851 7772912 1781238..1781534 1 NC_012578.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1781534 7772912 VCM66_1642 Vibrio cholerae M66-2 YciI-like protein YP_002810402.1 1781238 D 579112 CDS YP_002810403.1 227081852 7772913 1781443..1781934 1 NC_012578.1 hypothetical protein 1781934 7772913 VCM66_1643 Vibrio cholerae M66-2 hypothetical protein YP_002810403.1 1781443 D 579112 CDS YP_002810404.1 227081853 7772914 complement(1782209..1784494) 1 NC_012578.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1784494 metE 7772914 metE Vibrio cholerae M66-2 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_002810404.1 1782209 R 579112 CDS YP_002810405.1 227081854 7772915 1784748..1784843 1 NC_012578.1 hypothetical protein 1784843 7772915 VCM66_1645 Vibrio cholerae M66-2 hypothetical protein YP_002810405.1 1784748 D 579112 CDS YP_002810406.1 227081855 7772916 1784890..1785807 1 NC_012578.1 transcriptional activator MetR 1785807 metR 7772916 metR Vibrio cholerae M66-2 transcriptional activator MetR YP_002810406.1 1784890 D 579112 CDS YP_002810407.1 227081856 7772917 complement(1785814..1786017) 1 NC_012578.1 hypothetical protein 1786017 7772917 VCM66_1647 Vibrio cholerae M66-2 hypothetical protein YP_002810407.1 1785814 R 579112 CDS YP_002810408.1 227081857 7772918 complement(1786131..1786817) 1 NC_012578.1 hypothetical protein 1786817 7772918 VCM66_1648 Vibrio cholerae M66-2 hypothetical protein YP_002810408.1 1786131 R 579112 CDS YP_002810409.1 227081858 7772919 1787041..1789809 1 NC_012578.1 zinc protease, insulinase family 1789809 7772919 VCM66_1649 Vibrio cholerae M66-2 zinc protease, insulinase family YP_002810409.1 1787041 D 579112 CDS YP_002810410.1 227081859 7772920 complement(1789943..1792399) 1 NC_012578.1 PAS/EAL family protein 1792399 7772920 VCM66_1650 Vibrio cholerae M66-2 PAS/EAL family protein YP_002810410.1 1789943 R 579112 CDS YP_002810411.1 227081860 7772921 1792679..1795048 1 NC_012578.1 hypothetical protein 1795048 7772921 VCM66_1651 Vibrio cholerae M66-2 hypothetical protein YP_002810411.1 1792679 D 579112 CDS YP_002810412.1 227081861 7772922 complement(1795096..1795710) 1 NC_012578.1 hypothetical protein 1795710 7772922 VCM66_1652 Vibrio cholerae M66-2 hypothetical protein YP_002810412.1 1795096 R 579112 CDS YP_002810413.1 227081862 7772923 1795788..1796231 1 NC_012578.1 AsnC family transcriptional regulator 1796231 7772923 VCM66_1653 Vibrio cholerae M66-2 AsnC family transcriptional regulator YP_002810413.1 1795788 D 579112 CDS YP_002810414.1 227081863 7772924 complement(1796313..1800788) 1 NC_012578.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1800788 mukB 7772924 mukB Vibrio cholerae M66-2 cell division protein MukB YP_002810414.1 1796313 R 579112 CDS YP_002810415.1 227081864 7772925 complement(1800785..1801528) 1 NC_012578.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1801528 mukE 7772925 mukE Vibrio cholerae M66-2 condesin subunit E YP_002810415.1 1800785 R 579112 CDS YP_002810416.1 227081865 7772926 complement(1801488..1802825) 1 NC_012578.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1802825 mukF 7772926 mukF Vibrio cholerae M66-2 condesin subunit F YP_002810416.1 1801488 R 579112 CDS YP_002810417.1 227081866 7772927 complement(1802837..1803619) 1 NC_012578.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 1803619 smtA 7772927 smtA Vibrio cholerae M66-2 putative metallothionein SmtA YP_002810417.1 1802837 R 579112 CDS YP_002810418.1 227081867 7772928 1803709..1804557 1 NC_012578.1 hypothetical protein 1804557 7772928 VCM66_1658 Vibrio cholerae M66-2 hypothetical protein YP_002810418.1 1803709 D 579112 CDS YP_002810419.1 227081868 7772929 complement(1804657..1805361) 1 NC_012578.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1805361 torR 7772929 torR Vibrio cholerae M66-2 DNA-binding transcriptional regulator TorR YP_002810419.1 1804657 R 579112 CDS YP_002810420.1 227081869 7772930 1805586..1806248 1 NC_012578.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1806248 torD 7772930 torD Vibrio cholerae M66-2 chaperone protein TorD YP_002810420.1 1805586 D 579112 CDS YP_002810421.1 227081870 7772931 1806655..1807665 1 NC_012578.1 LacI family transcriptional regulator 1807665 7772931 VCM66_1661 Vibrio cholerae M66-2 LacI family transcriptional regulator YP_002810421.1 1806655 D 579112 CDS YP_002810422.1 227081871 7772932 1808024..1808611 1 NC_012578.1 hypothetical protein 1808611 7772932 VCM66_1662 Vibrio cholerae M66-2 hypothetical protein YP_002810422.1 1808024 D 579112 CDS YP_002810423.1 227081872 7772933 1808966..1809655 1 NC_012578.1 hypothetical protein 1809655 7772933 VCM66_1663 Vibrio cholerae M66-2 hypothetical protein YP_002810423.1 1808966 D 579112 CDS YP_002810424.1 227081873 7772934 1809689..1810000 1 NC_012578.1 hypothetical protein 1810000 7772934 VCM66_1664 Vibrio cholerae M66-2 hypothetical protein YP_002810424.1 1809689 D 579112 CDS YP_002810425.1 227081874 7772935 complement(1810005..1810823) 1 NC_012578.1 putative beta-ketoadipate enol-lactone hydrolase 1810823 7772935 VCM66_1665 Vibrio cholerae M66-2 putative beta-ketoadipate enol-lactone hydrolase YP_002810425.1 1810005 R 579112 CDS YP_002810426.1 227081875 7772936 complement(1811011..1812465) 1 NC_012578.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1812465 glgA 7772936 glgA Vibrio cholerae M66-2 glycogen synthase YP_002810426.1 1811011 R 579112 CDS YP_002810427.1 227081876 7772937 complement(1812467..1813684) 1 NC_012578.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1813684 glgC 7772937 glgC Vibrio cholerae M66-2 glucose-1-phosphate adenylyltransferase YP_002810427.1 1812467 R 579112 CDS YP_002810428.1 227081877 7772938 1813816..1813950 1 NC_012578.1 hypothetical protein 1813950 7772938 VCM66_1668 Vibrio cholerae M66-2 hypothetical protein YP_002810428.1 1813816 D 579112 CDS YP_002810429.1 227081878 7772939 complement(1814352..1816982) 1 NC_012578.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1816982 topA 7772939 topA Vibrio cholerae M66-2 DNA topoisomerase I YP_002810429.1 1814352 R 579112 CDS YP_002810430.1 227081879 7772940 1817319..1817567 1 NC_012578.1 hypothetical protein 1817567 7772940 VCM66_1671 Vibrio cholerae M66-2 hypothetical protein YP_002810430.1 1817319 D 579112 CDS YP_002810431.1 227081880 7772941 complement(1817658..1818938) 1 NC_012578.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1818938 aroA 7772941 aroA Vibrio cholerae M66-2 3-phosphoshikimate 1-carboxyvinyltransferase YP_002810431.1 1817658 R 579112 CDS YP_002810432.1 227081881 7772942 1818942..1819145 1 NC_012578.1 hypothetical protein 1819145 7772942 VCM66_1673 Vibrio cholerae M66-2 hypothetical protein YP_002810432.1 1818942 D 579112 CDS YP_002810433.1 227081882 7772943 1819120..1819224 1 NC_012578.1 hypothetical protein 1819224 7772943 VCM66_1674 Vibrio cholerae M66-2 hypothetical protein YP_002810433.1 1819120 D 579112 CDS YP_002810434.1 227081883 7772944 1819205..1819936 1 NC_012578.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1819936 aat 7772944 aat Vibrio cholerae M66-2 leucyl/phenylalanyl-tRNA--protein transferase YP_002810434.1 1819205 D 579112 CDS YP_002810435.1 227081884 7772945 1819940..1820641 1 NC_012578.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 1820641 7772945 VCM66_1676 Vibrio cholerae M66-2 arginyl-tRNA-protein transferase YP_002810435.1 1819940 D 579112 CDS YP_002810436.1 227081885 7772946 1820725..1820943 1 NC_012578.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1820943 infA 7772946 infA Vibrio cholerae M66-2 translation initiation factor IF-1 YP_002810436.1 1820725 D 579112 CDS YP_002810437.1 227081886 7772947 complement(1821247..1822458) 1 NC_012578.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase 1822458 7772947 VCM66_1678 Vibrio cholerae M66-2 trans-2-enoyl-CoA reductase YP_002810437.1 1821247 R 579112 CDS YP_002810438.1 227081887 7772948 complement(1822651..1824933) 1 NC_012578.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 1824933 7772948 VCM66_1679 Vibrio cholerae M66-2 acyl-CoA dehydrogenase YP_002810438.1 1822651 R 579112 CDS YP_002810439.1 227081888 7772949 complement(1824989..1825663) 1 NC_012578.1 TetR family transcriptional regulator 1825663 7772949 VCM66_1680 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002810439.1 1824989 R 579112 CDS YP_002810440.1 227081889 7772950 1825918..1826055 1 NC_012578.1 hypothetical protein 1826055 7772950 VCM66_1681 Vibrio cholerae M66-2 hypothetical protein YP_002810440.1 1825918 D 579112 CDS YP_002810441.1 227081890 7772951 1826034..1827059 1 NC_012578.1 hypothetical protein 1827059 7772951 VCM66_1682 Vibrio cholerae M66-2 hypothetical protein YP_002810441.1 1826034 D 579112 CDS YP_002810442.1 227081891 7772952 1827104..1827385 1 NC_012578.1 hypothetical protein 1827385 7772952 VCM66_1683 Vibrio cholerae M66-2 hypothetical protein YP_002810442.1 1827104 D 579112 CDS YP_002810443.1 227081892 7772953 complement(1827366..1828832) 1 NC_012578.1 succinate-semialdehyde dehydrogenase 1828832 gabD 7772953 gabD Vibrio cholerae M66-2 succinate-semialdehyde dehydrogenase YP_002810443.1 1827366 R 579112 CDS YP_002810444.1 227081893 7772954 complement(1828850..1829479) 1 NC_012578.1 TetR family transcriptional regulator 1829479 7772954 VCM66_1685 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002810444.1 1828850 R 579112 CDS YP_002810445.1 227081894 7772955 1829405..1829629 1 NC_012578.1 hypothetical protein 1829629 7772955 VCM66_1686 Vibrio cholerae M66-2 hypothetical protein YP_002810445.1 1829405 D 579112 CDS YP_002810446.1 227081895 7772956 1829706..1830530 1 NC_012578.1 hypothetical protein 1830530 7772956 VCM66_1687 Vibrio cholerae M66-2 hypothetical protein YP_002810446.1 1829706 D 579112 CDS YP_002810447.1 227081896 7772957 1830430..1831656 1 NC_012578.1 hypothetical protein 1831656 7772957 VCM66_1688 Vibrio cholerae M66-2 hypothetical protein YP_002810447.1 1830430 D 579112 CDS YP_002810448.1 227081897 7772958 1831667..1832788 1 NC_012578.1 hypothetical protein 1832788 7772958 VCM66_1689 Vibrio cholerae M66-2 hypothetical protein YP_002810448.1 1831667 D 579112 CDS YP_002810449.1 227081898 7772959 complement(1832804..1833682) 1 NC_012578.1 Small-conductance mechanosensitive channel 1833682 7772959 VCM66_1690 Vibrio cholerae M66-2 Small-conductance mechanosensitive channel YP_002810449.1 1832804 R 579112 CDS YP_002810450.1 227081899 7772960 1834446..1834571 1 NC_012578.1 hypothetical protein 1834571 7772960 VCM66_1691 Vibrio cholerae M66-2 hypothetical protein YP_002810450.1 1834446 D 579112 CDS YP_002810451.1 227081900 7772961 1834735..1836039 1 NC_012578.1 paraquat-inducible protein A 1836039 pqiA 7772961 pqiA Vibrio cholerae M66-2 paraquat-inducible protein A YP_002810451.1 1834735 D 579112 CDS YP_002810452.1 227081901 7772962 1836036..1837679 1 NC_012578.1 paraquat-inducible protein B 1837679 pqiB 7772962 pqiB Vibrio cholerae M66-2 paraquat-inducible protein B YP_002810452.1 1836036 D 579112 CDS YP_002810453.1 227081902 7772963 1837676..1838254 1 NC_012578.1 putative lipoprotein 1838254 7772963 VCM66_1694 Vibrio cholerae M66-2 putative lipoprotein YP_002810453.1 1837676 D 579112 CDS YP_002810454.1 227081903 7772964 1838470..1839564 1 NC_012578.1 putative periplasmic linker protein 1839564 7772964 VCM66_1695 Vibrio cholerae M66-2 putative periplasmic linker protein YP_002810454.1 1838470 D 579112 CDS YP_002810455.1 227081904 7772965 1839564..1842614 1 NC_012578.1 transporter, AcrB/D/F family 1842614 7772965 VCM66_1696 Vibrio cholerae M66-2 transporter, AcrB/D/F family YP_002810455.1 1839564 D 579112 CDS YP_002810456.1 227081905 7774065 1843226..1844461 1 NC_012578.1 integrase, phage family 1844461 7774065 VCM66_1697 Vibrio cholerae M66-2 integrase, phage family YP_002810456.1 1843226 D 579112 CDS YP_002810457.1 227081906 7773961 complement(1845143..1848592) 1 NC_012578.1 putative helicase 1848592 7773961 VCM66_1699 Vibrio cholerae M66-2 putative helicase YP_002810457.1 1845143 R 579112 CDS YP_002810458.1 227081907 7772968 complement(1848583..1850034) 1 NC_012578.1 hypothetical protein 1850034 7772968 VCM66_1700 Vibrio cholerae M66-2 hypothetical protein YP_002810458.1 1848583 R 579112 CDS YP_002810459.1 227081908 7772969 complement(1850031..1850765) 1 NC_012578.1 chemotaxis protein MotB-like protein 1850765 7772969 VCM66_1701 Vibrio cholerae M66-2 chemotaxis protein MotB-like protein YP_002810459.1 1850031 R 579112 CDS YP_002810460.1 227081909 7772970 complement(1850758..1852878) 1 NC_012578.1 Restin-like protein 1852878 7772970 VCM66_1702 Vibrio cholerae M66-2 Restin-like protein YP_002810460.1 1850758 R 579112 CDS YP_002810461.1 227081910 7772971 complement(1852923..1855991) 1 NC_012578.1 putative type I restriction enzyme HsdR 1855991 7772971 VCM66_1703 Vibrio cholerae M66-2 putative type I restriction enzyme HsdR YP_002810461.1 1852923 R 579112 CDS YP_002810462.1 227081911 7772972 complement(1856019..1858010) 1 NC_012578.1 hypothetical protein 1858010 7772972 VCM66_1704 Vibrio cholerae M66-2 hypothetical protein YP_002810462.1 1856019 R 579112 CDS YP_002810463.1 227081912 7772973 complement(1858003..1859415) 1 NC_012578.1 hypothetical protein 1859415 7772973 VCM66_1705 Vibrio cholerae M66-2 hypothetical protein YP_002810463.1 1858003 R 579112 CDS YP_002810464.1 227081913 7772974 complement(1859416..1860804) 1 NC_012578.1 hypothetical protein 1860804 7772974 VCM66_1706 Vibrio cholerae M66-2 hypothetical protein YP_002810464.1 1859416 R 579112 CDS YP_002810465.1 227081914 7772975 complement(1860761..1863142) 1 NC_012578.1 putative DNA methylase HsdM 1863142 7772975 VCM66_1707 Vibrio cholerae M66-2 putative DNA methylase HsdM YP_002810465.1 1860761 R 579112 CDS YP_002810466.1 227081915 7772976 complement(1863283..1865346) 1 NC_012578.1 hypothetical protein 1865346 7772976 VCM66_1708 Vibrio cholerae M66-2 hypothetical protein YP_002810466.1 1863283 R 579112 CDS YP_002810467.1 227081916 7772977 complement(1865328..1868990) 1 NC_012578.1 hypothetical protein 1868990 7772977 VCM66_1709 Vibrio cholerae M66-2 hypothetical protein YP_002810467.1 1865328 R 579112 CDS YP_002810468.1 227081917 7772978 1869018..1869878 1 NC_012578.1 hypothetical protein 1869878 7772978 VCM66_1710 Vibrio cholerae M66-2 hypothetical protein YP_002810468.1 1869018 D 579112 CDS YP_002810469.1 227081918 7772979 complement(1869943..1871013) 1 NC_012578.1 hypothetical protein 1871013 7772979 VCM66_1711 Vibrio cholerae M66-2 hypothetical protein YP_002810469.1 1869943 R 579112 CDS YP_002810470.1 227081919 7772980 complement(1871028..1872182) 1 NC_012578.1 N-acetylneuraminic acid mutarotase 1872182 7772980 VCM66_1712 Vibrio cholerae M66-2 N-acetylneuraminic acid mutarotase YP_002810470.1 1871028 R 579112 CDS YP_002810471.1 227081920 7772981 complement(1872364..1873200) 1 NC_012578.1 Putative HTH-type transcriptional regulator ybbH 1873200 7772981 VCM66_1713 Vibrio cholerae M66-2 Putative HTH-type transcriptional regulator ybbH YP_002810471.1 1872364 R 579112 CDS YP_002810472.1 227081921 7772982 complement(1873329..1874225) 1 NC_012578.1 putative N-acetylneuraminate lyase 1874225 7772982 VCM66_1714 Vibrio cholerae M66-2 putative N-acetylneuraminate lyase YP_002810472.1 1873329 R 579112 CDS YP_002810473.1 227081922 7772983 complement(1874263..1875546) 1 NC_012578.1 Sialic acid TRAP transporter,large permease 1875546 7772983 VCM66_1715 Vibrio cholerae M66-2 Sialic acid TRAP transporter,large permease YP_002810473.1 1874263 R 579112 CDS YP_002810474.1 227081923 7772984 complement(1875554..1876075) 1 NC_012578.1 Sialic acid TRAP transporter small permease 1876075 7772984 VCM66_1716 Vibrio cholerae M66-2 Sialic acid TRAP transporter small permease YP_002810474.1 1875554 R 579112 CDS YP_002810475.1 227081924 7772985 complement(1876126..1877091) 1 NC_012578.1 C4-dicarboxylate-binding periplasmic protein 1877091 dctP-1 7772985 dctP-1 Vibrio cholerae M66-2 C4-dicarboxylate-binding periplasmic protein YP_002810475.1 1876126 R 579112 CDS YP_002810476.1 227081925 7772986 1877122..1877415 1 NC_012578.1 hypothetical protein 1877415 7772986 VCM66_1718 Vibrio cholerae M66-2 hypothetical protein YP_002810476.1 1877122 D 579112 CDS YP_002810477.1 227081926 7772987 1877306..1878028 1 NC_012578.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1878028 7772987 VCM66_1719 Vibrio cholerae M66-2 N-acetylmannosamine-6-phosphate 2-epimerase YP_002810477.1 1877306 D 579112 CDS YP_002810478.1 227081927 7772988 1878016..1878879 1 NC_012578.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1878879 7772988 VCM66_1720 Vibrio cholerae M66-2 N-acetylmannosamine kinase YP_002810478.1 1878016 D 579112 CDS YP_002810479.1 227081928 7772989 1878883..1880019 1 NC_012578.1 N-acetylglucosamine-6-phosphate deacetylase 1880019 nagA-2 7772989 nagA-2 Vibrio cholerae M66-2 N-acetylglucosamine-6-phosphate deacetylase YP_002810479.1 1878883 D 579112 CDS YP_002810480.1 227081929 7772990 1880364..1882787 1 NC_012578.1 neuraminidase 1882787 nanH 7772990 nanH Vibrio cholerae M66-2 neuraminidase YP_002810480.1 1880364 D 579112 CDS YP_002810481.1 227081930 7772991 complement(1882934..1883140) 1 NC_012578.1 transcriptional regulator 1883140 7772991 VCM66_1723 Vibrio cholerae M66-2 transcriptional regulator YP_002810481.1 1882934 R 579112 CDS YP_002810482.1 227081931 7772992 1883254..1883730 1 NC_012578.1 putative DNA repair protein RadC 1883730 7772992 VCM66_1724 Vibrio cholerae M66-2 putative DNA repair protein RadC YP_002810482.1 1883254 D 579112 CDS YP_002810483.1 227081932 7772993 1883727..1883864 1 NC_012578.1 hypothetical protein 1883864 7772993 VCM66_1725 Vibrio cholerae M66-2 hypothetical protein YP_002810483.1 1883727 D 579112 CDS YP_002810484.1 227081933 7772994 complement(1883960..1884655) 1 NC_012578.1 hypothetical protein 1884655 7772994 VCM66_1726 Vibrio cholerae M66-2 hypothetical protein YP_002810484.1 1883960 R 579112 CDS YP_002810485.1 227081934 7772995 complement(1884652..1885524) 1 NC_012578.1 ISVch4 transposase, OrfB 1885524 orfB 7772995 orfB Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002810485.1 1884652 R 579112 CDS YP_002810486.1 227081935 7772996 complement(1885521..1885865) 1 NC_012578.1 ISVch4 transposase, OrfA 1885865 orfA 7772996 orfA Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002810486.1 1885521 R 579112 CDS YP_002810487.1 227081936 7772997 1886108..1887094 1 NC_012578.1 hypothetical protein 1887094 7772997 VCM66_1729 Vibrio cholerae M66-2 hypothetical protein YP_002810487.1 1886108 D 579112 CDS YP_002810488.1 227081937 7773962 1888061..1888906 1 NC_012578.1 hypothetical protein 1888906 7773962 VCM66_1731 Vibrio cholerae M66-2 hypothetical protein YP_002810488.1 1888061 D 579112 CDS YP_002810489.1 227081938 7772999 complement(1889021..1889251) 1 NC_012578.1 putative transcriptional regulator 1889251 7772999 VCM66_1732 Vibrio cholerae M66-2 putative transcriptional regulator YP_002810489.1 1889021 R 579112 CDS YP_002810490.1 227081939 7773000 1889851..1890054 1 NC_012578.1 hypothetical protein 1890054 7773000 VCM66_1733 Vibrio cholerae M66-2 hypothetical protein YP_002810490.1 1889851 D 579112 CDS YP_002810491.1 227081940 7773001 complement(1890046..1890519) 1 NC_012578.1 hypothetical protein 1890519 7773001 VCM66_1734 Vibrio cholerae M66-2 hypothetical protein YP_002810491.1 1890046 R 579112 CDS YP_002810492.1 227081941 7773002 complement(1890643..1891062) 1 NC_012578.1 hypothetical protein 1891062 7773002 VCM66_1735 Vibrio cholerae M66-2 hypothetical protein YP_002810492.1 1890643 R 579112 CDS YP_002810493.1 227081942 7773003 complement(1891031..1891123) 1 NC_012578.1 hypothetical protein 1891123 7773003 VCM66_1736 Vibrio cholerae M66-2 hypothetical protein YP_002810493.1 1891031 R 579112 CDS YP_002810494.1 227081943 7773004 1891179..1892564 1 NC_012578.1 deoxyribodipyrimidine photolyase 1892564 phrB-1 7773004 phrB-1 Vibrio cholerae M66-2 deoxyribodipyrimidine photolyase YP_002810494.1 1891179 D 579112 CDS YP_002810495.1 227081944 7773005 1892561..1893268 1 NC_012578.1 C factor cell-cell signaling protein 1893268 7773005 VCM66_1738 Vibrio cholerae M66-2 C factor cell-cell signaling protein YP_002810495.1 1892561 D 579112 CDS YP_002810496.1 227081945 7773006 complement(1893279..1893494) 1 NC_012578.1 hypothetical protein 1893494 7773006 VCM66_1739 Vibrio cholerae M66-2 hypothetical protein YP_002810496.1 1893279 R 579112 CDS YP_002810497.1 227081946 7773007 complement(1893591..1895354) 1 NC_012578.1 sigma-54 dependent transcriptional regulator 1895354 7773007 VCM66_1740 Vibrio cholerae M66-2 sigma-54 dependent transcriptional regulator YP_002810497.1 1893591 R 579112 CDS YP_002810498.1 227081947 7773008 complement(1895522..1895623) 1 NC_012578.1 hypothetical protein 1895623 7773008 VCM66_1741 Vibrio cholerae M66-2 hypothetical protein YP_002810498.1 1895522 R 579112 CDS YP_002810499.1 227081948 7773009 1895635..1897155 1 NC_012578.1 aldehyde dehydrogenase 1897155 aldA-2 7773009 aldA-2 Vibrio cholerae M66-2 aldehyde dehydrogenase YP_002810499.1 1895635 D 579112 CDS YP_002810500.1 227081949 7773010 1897488..1897928 1 NC_012578.1 PTS system fructose-specific transporter subunit IIA 1897928 frvA 7773010 frvA Vibrio cholerae M66-2 PTS system fructose-specific transporter subunit IIA YP_002810500.1 1897488 D 579112 CDS YP_002810501.1 227081950 7773011 1897940..1899343 1 NC_012578.1 PTS system fructose-specific transporter subunit IIBC 1899343 frwBC 7773011 frwBC Vibrio cholerae M66-2 PTS system fructose-specific transporter subunit IIBC YP_002810501.1 1897940 D 579112 CDS YP_002810502.1 227081951 7773012 complement(1899418..1901283) 1 NC_012578.1 PTS system fructose-specific transporter subunit IIABC 1901283 frwABC 7773012 frwABC Vibrio cholerae M66-2 PTS system fructose-specific transporter subunit IIABC YP_002810502.1 1899418 R 579112 CDS YP_002810503.1 227081952 7773013 1901500..1901799 1 NC_012578.1 PTS system fructose-specific transporter subunit IIB 1901799 frwB 7773013 frwB Vibrio cholerae M66-2 PTS system fructose-specific transporter subunit IIB YP_002810503.1 1901500 D 579112 CDS YP_002810504.1 227081953 7773014 1901808..1902587 1 NC_012578.1 putative PTS system, nitrogen regulatory IIA component 1902587 7773014 VCM66_1747 Vibrio cholerae M66-2 putative PTS system, nitrogen regulatory IIA component YP_002810504.1 1901808 D 579112 CDS YP_002810505.1 227081954 7773015 complement(1902579..1903418) 1 NC_012578.1 transcriptional regulator 1903418 7773015 VCM66_1748 Vibrio cholerae M66-2 transcriptional regulator YP_002810505.1 1902579 R 579112 CDS YP_002810506.1 227081955 7773016 1903790..1905691 1 NC_012578.1 PTS system fructose-specific transporter subunit IIABC 1905691 fruA-1 7773016 fruA-1 Vibrio cholerae M66-2 PTS system fructose-specific transporter subunit IIABC YP_002810506.1 1903790 D 579112 CDS YP_002810507.1 227081956 7773017 1905807..1906973 1 NC_012578.1 mannose-6-phosphate isomerase 1906973 manA-2 7773017 manA-2 Vibrio cholerae M66-2 mannose-6-phosphate isomerase YP_002810507.1 1905807 D 579112 CDS YP_002810508.1 227081957 7773018 complement(1907093..1907545) 1 NC_012578.1 hypothetical protein 1907545 7773018 VCM66_1751 Vibrio cholerae M66-2 hypothetical protein YP_002810508.1 1907093 R 579112 CDS YP_002810509.1 227081958 7773019 complement(1907734..1907841) 1 NC_012578.1 hypothetical protein 1907841 7773019 VCM66_1752 Vibrio cholerae M66-2 hypothetical protein YP_002810509.1 1907734 R 579112 CDS YP_002810510.1 227081959 7773020 1907819..1907914 1 NC_012578.1 hypothetical protein 1907914 7773020 VCM66_1753 Vibrio cholerae M66-2 hypothetical protein YP_002810510.1 1907819 D 579112 CDS YP_002810511.1 227081960 7773021 complement(1907881..1910091) 1 NC_012578.1 sensor histidine kinase 1910091 7773021 VCM66_1754 Vibrio cholerae M66-2 sensor histidine kinase YP_002810511.1 1907881 R 579112 CDS YP_002810512.1 227081961 7773022 1910299..1910871 1 NC_012578.1 hypothetical protein 1910871 7773022 VCM66_1755 Vibrio cholerae M66-2 hypothetical protein YP_002810512.1 1910299 D 579112 CDS YP_002810513.1 227081962 7773023 complement(1910945..1912006) 1 NC_012578.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1912006 nadA 7773023 nadA Vibrio cholerae M66-2 quinolinate synthetase YP_002810513.1 1910945 R 579112 CDS YP_002810514.1 227081963 7773024 complement(1912180..1912944) 1 NC_012578.1 hypothetical protein 1912944 7773024 VCM66_1757 Vibrio cholerae M66-2 hypothetical protein YP_002810514.1 1912180 R 579112 CDS YP_002810515.1 227081964 7773025 complement(1912960..1913478) 1 NC_012578.1 peptidoglycan-associated lipoprotein 1913478 pal 7773025 pal Vibrio cholerae M66-2 peptidoglycan-associated lipoprotein YP_002810515.1 1912960 R 579112 CDS YP_002810516.1 227081965 7773026 complement(1913510..1914862) 1 NC_012578.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1914862 tolB 7773026 tolB Vibrio cholerae M66-2 translocation protein TolB YP_002810516.1 1913510 R 579112 CDS YP_002810517.1 227081966 7773027 complement(1914877..1915947) 1 NC_012578.1 tolA protein 1915947 tolA 7773027 tolA Vibrio cholerae M66-2 tolA protein YP_002810517.1 1914877 R 579112 CDS YP_002810518.1 227081967 7773028 complement(1915965..1916405) 1 NC_012578.1 tolR membrane protein 1916405 tolR 7773028 tolR Vibrio cholerae M66-2 tolR membrane protein YP_002810518.1 1915965 R 579112 CDS YP_002810519.1 227081968 7773029 complement(1916408..1917091) 1 NC_012578.1 tolQ protein 1917091 tolQ 7773029 tolQ Vibrio cholerae M66-2 tolQ protein YP_002810519.1 1916408 R 579112 CDS YP_002810520.1 227081969 7773030 complement(1917081..1917548) 1 NC_012578.1 hypothetical protein 1917548 7773030 VCM66_1763 Vibrio cholerae M66-2 hypothetical protein YP_002810520.1 1917081 R 579112 CDS YP_002810521.1 227081970 7773031 complement(1917657..1917974) 1 NC_012578.1 hypothetical protein 1917974 7773031 VCM66_1764 Vibrio cholerae M66-2 hypothetical protein YP_002810521.1 1917657 R 579112 CDS YP_002810522.1 227081971 7773032 complement(1917967..1918074) 1 NC_012578.1 hypothetical protein 1918074 7773032 VCM66_1765 Vibrio cholerae M66-2 hypothetical protein YP_002810522.1 1917967 R 579112 CDS YP_002810523.1 227081972 7773033 complement(1918087..1919223) 1 NC_012578.1 cytochrome d ubiquinol oxidase subunit II 1919223 cydB-1 7773033 cydB-1 Vibrio cholerae M66-2 cytochrome d ubiquinol oxidase subunit II YP_002810523.1 1918087 R 579112 CDS YP_002810524.1 227081973 7773034 complement(1919241..1920866) 1 NC_012578.1 cytochrome d ubiquinol oxidase subunit I 1920866 cydA-1 7773034 cydA-1 Vibrio cholerae M66-2 cytochrome d ubiquinol oxidase subunit I YP_002810524.1 1919241 R 579112 CDS YP_002810525.1 227081974 7773035 complement(1921286..1922290) 1 NC_012578.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1922290 ruvB 7773035 ruvB Vibrio cholerae M66-2 Holliday junction DNA helicase RuvB YP_002810525.1 1921286 R 579112 CDS YP_002810526.1 227081975 7773036 complement(1922346..1922960) 1 NC_012578.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1922960 ruvA 7773036 ruvA Vibrio cholerae M66-2 Holliday junction DNA helicase RuvA YP_002810526.1 1922346 R 579112 CDS YP_002810527.1 227081976 7773037 complement(1923057..1923578) 1 NC_012578.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1923578 ruvC 7773037 ruvC Vibrio cholerae M66-2 Holliday junction resolvase YP_002810527.1 1923057 R 579112 CDS YP_002810528.1 227081977 7773038 complement(1923666..1925045) 1 NC_012578.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1925045 cysS 7773038 cysS Vibrio cholerae M66-2 cysteinyl-tRNA synthetase YP_002810528.1 1923666 R 579112 CDS YP_002810529.1 227081978 7773039 1925191..1925685 1 NC_012578.1 peptidyl-prolyl cis-trans isomerase B 1925685 ppiB 7773039 ppiB Vibrio cholerae M66-2 peptidyl-prolyl cis-trans isomerase B YP_002810529.1 1925191 D 579112 CDS YP_002810530.1 227081979 7773040 1925726..1926466 1 NC_012578.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1926466 7773040 VCM66_1773 Vibrio cholerae M66-2 UDP-2,3-diacylglucosamine hydrolase YP_002810530.1 1925726 D 579112 CDS YP_002810531.1 227081980 7773041 1926562..1927776 1 NC_012578.1 HD-GYP/EAL family protein 1927776 7773041 VCM66_1774 Vibrio cholerae M66-2 HD-GYP/EAL family protein YP_002810531.1 1926562 D 579112 CDS YP_002810532.1 227081981 7773042 1927838..1928293 1 NC_012578.1 hypothetical protein 1928293 7773042 VCM66_1775 Vibrio cholerae M66-2 hypothetical protein YP_002810532.1 1927838 D 579112 CDS YP_002810533.1 227081982 7773043 complement(1928325..1928999) 1 NC_012578.1 hypothetical protein 1928999 7773043 VCM66_1776 Vibrio cholerae M66-2 hypothetical protein YP_002810533.1 1928325 R 579112 CDS YP_002810534.1 227081983 7773044 complement(1929118..1930224) 1 NC_012578.1 ompT protein 1930224 ompT 7773044 ompT Vibrio cholerae M66-2 ompT protein YP_002810534.1 1929118 R 579112 CDS YP_002810535.1 227081984 7773045 1930627..1932738 1 NC_012578.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 1932738 dinG 7773045 dinG Vibrio cholerae M66-2 ATP-dependent DNA helicase DinG YP_002810535.1 1930627 D 579112 CDS YP_002810536.1 227081985 7773046 1932776..1933555 1 NC_012578.1 putative Inner membrane protein 1933555 7773046 VCM66_1779 Vibrio cholerae M66-2 putative Inner membrane protein YP_002810536.1 1932776 D 579112 CDS YP_002810537.1 227081986 7773047 1933540..1934103 1 NC_012578.1 primosomal replication protein N'' 1934103 priC 7773047 priC Vibrio cholerae M66-2 primosomal replication protein N'' YP_002810537.1 1933540 D 579112 CDS YP_002810538.1 227081987 7773048 1934104..1934316 1 NC_012578.1 hypothetical protein 1934316 7773048 VCM66_1781 Vibrio cholerae M66-2 hypothetical protein YP_002810538.1 1934104 D 579112 CDS YP_002810539.1 227081988 7773049 complement(1934340..1936460) 1 NC_012578.1 methyl-accepting chemotaxis protein 1936460 7773049 VCM66_1782 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810539.1 1934340 R 579112 CDS YP_002810540.1 227081989 7773050 1936658..1937464 1 NC_012578.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1937464 xth 7773050 xth Vibrio cholerae M66-2 exonuclease III YP_002810540.1 1936658 D 579112 CDS YP_002810541.1 227081990 7773051 complement(1937523..1938200) 1 NC_012578.1 amino acid ABC transporter permease 1938200 7773051 VCM66_1784 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002810541.1 1937523 R 579112 CDS YP_002810542.1 227081991 7773052 complement(1938203..1938985) 1 NC_012578.1 amino acid ABC transporter permease 1938985 7773052 VCM66_1785 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002810542.1 1938203 R 579112 CDS YP_002810543.1 227081992 7773053 complement(1939091..1939873) 1 NC_012578.1 amino acid ABC transporter substrate-binding protein 1939873 7773053 VCM66_1786 Vibrio cholerae M66-2 amino acid ABC transporter substrate-binding protein YP_002810543.1 1939091 R 579112 CDS YP_002810544.1 227081993 7773054 complement(1940052..1940822) 1 NC_012578.1 amino acid ABC transporter ATP-binding protein 1940822 7773054 VCM66_1787 Vibrio cholerae M66-2 amino acid ABC transporter ATP-binding protein YP_002810544.1 1940052 R 579112 CDS YP_002810545.1 227081994 7773055 1941527..1943083 1 NC_012578.1 hypothetical protein 1943083 7773055 VCM66_1788 Vibrio cholerae M66-2 hypothetical protein YP_002810545.1 1941527 D 579112 CDS YP_002810546.1 227081995 7773056 1943262..1945625 1 NC_012578.1 formate acetyltransferase 1945625 pflB 7773056 pflB Vibrio cholerae M66-2 formate acetyltransferase YP_002810546.1 1943262 D 579112 CDS YP_002810547.1 227081996 7773057 1945761..1946789 1 NC_012578.1 hypothetical protein 1946789 7773057 VCM66_1790 Vibrio cholerae M66-2 hypothetical protein YP_002810547.1 1945761 D 579112 CDS YP_002810548.1 227081997 7773058 complement(1946807..1948687) 1 NC_012578.1 methyl-accepting chemotaxis protein 1948687 7773058 VCM66_1791 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810548.1 1946807 R 579112 CDS YP_002810549.1 227081998 7773059 1949020..1949760 1 NC_012578.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1949760 pflA 7773059 pflA Vibrio cholerae M66-2 pyruvate formate lyase-activating enzyme 1 YP_002810549.1 1949020 D 579112 CDS YP_002810550.1 227081999 7773060 1949826..1950488 1 NC_012578.1 hypothetical protein 1950488 7773060 VCM66_1793 Vibrio cholerae M66-2 hypothetical protein YP_002810550.1 1949826 D 579112 CDS YP_002810551.1 227082000 7773061 1950597..1951109 1 NC_012578.1 hypothetical protein 1951109 7773061 VCM66_1794 Vibrio cholerae M66-2 hypothetical protein YP_002810551.1 1950597 D 579112 CDS YP_002810552.1 227082001 7773062 1951350..1953284 1 NC_012578.1 hypothetical protein 1953284 7773062 VCM66_1795 Vibrio cholerae M66-2 hypothetical protein YP_002810552.1 1951350 D 579112 CDS YP_002810553.1 227082002 7773063 1953429..1954700 1 NC_012578.1 hypothetical protein 1954700 7773063 VCM66_1796 Vibrio cholerae M66-2 hypothetical protein YP_002810553.1 1953429 D 579112 CDS YP_002810554.1 227082003 7773064 1954713..1956263 1 NC_012578.1 SpoVR family protein 1956263 7773064 VCM66_1797 Vibrio cholerae M66-2 SpoVR family protein YP_002810554.1 1954713 D 579112 CDS YP_002810555.1 227082004 7773065 complement(1956364..1956801) 1 NC_012578.1 IS1004 transposase 1956801 7773065 VCM66_1798 Vibrio cholerae M66-2 IS1004 transposase YP_002810555.1 1956364 R 579112 CDS YP_002810556.1 227082005 7773066 complement(1956970..1957728) 1 NC_012578.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1957728 kdsB 7773066 kdsB Vibrio cholerae M66-2 3-deoxy-manno-octulosonate cytidylyltransferase YP_002810556.1 1956970 R 579112 CDS YP_002810557.1 227082006 7773067 complement(1957728..1957907) 1 NC_012578.1 hypothetical protein 1957907 7773067 VCM66_1800 Vibrio cholerae M66-2 hypothetical protein YP_002810557.1 1957728 R 579112 CDS YP_002810558.1 227082007 7773068 complement(1957888..1958898) 1 NC_012578.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1958898 lpxK 7773068 lpxK Vibrio cholerae M66-2 tetraacyldisaccharide 4'-kinase YP_002810558.1 1957888 R 579112 CDS YP_002810559.1 227082008 7773069 complement(1958898..1960646) 1 NC_012578.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1960646 msbA 7773069 msbA Vibrio cholerae M66-2 lipid transporter ATP-binding/permease YP_002810559.1 1958898 R 579112 CDS YP_002810560.1 227082009 7773070 complement(1960677..1962935) 1 NC_012578.1 Rec2-like protein 1962935 7773070 VCM66_1803 Vibrio cholerae M66-2 Rec2-like protein YP_002810560.1 1960677 R 579112 CDS YP_002810561.1 227082010 7773071 1962929..1963459 1 NC_012578.1 hypothetical protein 1963459 7773071 VCM66_1804 Vibrio cholerae M66-2 hypothetical protein YP_002810561.1 1962929 D 579112 CDS YP_002810562.1 227082011 7773072 1963468..1963605 1 NC_012578.1 hypothetical protein 1963605 7773072 VCM66_1805 Vibrio cholerae M66-2 hypothetical protein YP_002810562.1 1963468 D 579112 CDS YP_002810563.1 227082012 7773073 complement(1963574..1964818) 1 NC_012578.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1964818 7773073 VCM66_1806 Vibrio cholerae M66-2 outer membrane-specific lipoprotein transporter subunit LolE YP_002810563.1 1963574 R 579112 CDS YP_002810564.1 227082013 7773074 complement(1964819..1965505) 1 NC_012578.1 ABC transporter ATP-binding protein 1965505 7773074 VCM66_1807 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002810564.1 1964819 R 579112 CDS YP_002810565.1 227082014 7773075 complement(1965498..1966718) 1 NC_012578.1 Lipoprotein-releasing system transmembrane protein lolC 1966718 7773075 VCM66_1808 Vibrio cholerae M66-2 Lipoprotein-releasing system transmembrane protein lolC YP_002810565.1 1965498 R 579112 CDS YP_002810566.1 227082015 7773076 1966882..1967457 1 NC_012578.1 hypothetical protein 1967457 7773076 VCM66_1809 Vibrio cholerae M66-2 hypothetical protein YP_002810566.1 1966882 D 579112 CDS YP_002810567.1 227082016 7773077 1967460..1970927 1 NC_012578.1 transcription-repair coupling factor 1970927 mfd 7773077 mfd Vibrio cholerae M66-2 transcription-repair coupling factor YP_002810567.1 1967460 D 579112 CDS YP_002810568.1 227082017 7773078 1971067..1971867 1 NC_012578.1 hypothetical protein 1971867 7773078 VCM66_1811 Vibrio cholerae M66-2 hypothetical protein YP_002810568.1 1971067 D 579112 CDS YP_002810569.1 227082018 7773079 1972202..1974277 1 NC_012578.1 hemolysin-like protein 1974277 7773079 VCM66_1812 Vibrio cholerae M66-2 hemolysin-like protein YP_002810569.1 1972202 D 579112 CDS YP_002810570.1 227082019 7773080 1974562..1975098 1 NC_012578.1 putative ribosomal-protein-serine acetyltransferase 1975098 7773080 VCM66_1813 Vibrio cholerae M66-2 putative ribosomal-protein-serine acetyltransferase YP_002810570.1 1974562 D 579112 CDS YP_002810571.1 227082020 7773081 complement(1975211..1976515) 1 NC_012578.1 NADH dehydrogenase 1976515 ndh 7773081 ndh Vibrio cholerae M66-2 NADH dehydrogenase YP_002810571.1 1975211 R 579112 CDS YP_002810572.1 227082021 7773082 1976601..1976741 1 NC_012578.1 hypothetical protein 1976741 7773082 VCM66_1815 Vibrio cholerae M66-2 hypothetical protein YP_002810572.1 1976601 D 579112 CDS YP_002810573.1 227082022 7773083 complement(1976858..1977397) 1 NC_012578.1 hypothetical protein 1977397 7773083 VCM66_1816 Vibrio cholerae M66-2 hypothetical protein YP_002810573.1 1976858 R 579112 CDS YP_002810574.1 227082023 7773084 complement(1977577..1978437) 1 NC_012578.1 hypothetical protein 1978437 7773084 VCM66_1817 Vibrio cholerae M66-2 hypothetical protein YP_002810574.1 1977577 R 579112 CDS YP_002810575.1 227082024 7773085 complement(1978465..1979055) 1 NC_012578.1 hypothetical protein 1979055 7773085 VCM66_1818 Vibrio cholerae M66-2 hypothetical protein YP_002810575.1 1978465 R 579112 CDS YP_002810576.1 227082025 7773086 complement(1979108..1979497) 1 NC_012578.1 hypothetical protein 1979497 7773086 VCM66_1819 Vibrio cholerae M66-2 hypothetical protein YP_002810576.1 1979108 R 579112 CDS YP_002810577.1 227082026 7773087 complement(1979497..1980915) 1 NC_012578.1 hypothetical protein 1980915 7773087 VCM66_1820 Vibrio cholerae M66-2 hypothetical protein YP_002810577.1 1979497 R 579112 CDS YP_002810578.1 227082027 7773088 complement(1980928..1981278) 1 NC_012578.1 Hit family protein 1981278 7773088 VCM66_1821 Vibrio cholerae M66-2 Hit family protein YP_002810578.1 1980928 R 579112 CDS YP_002810579.1 227082028 7773089 1981511..1983529 1 NC_012578.1 methyl-accepting chemotaxis protein 1983529 7773089 VCM66_1822 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810579.1 1981511 D 579112 CDS YP_002810580.1 227082029 7773090 1983699..1984850 1 NC_012578.1 hypothetical protein 1984850 7773090 VCM66_1823 Vibrio cholerae M66-2 hypothetical protein YP_002810580.1 1983699 D 579112 CDS YP_002810581.1 227082030 7773091 complement(1985085..1985924) 1 NC_012578.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1985924 fadR 7773091 fadR Vibrio cholerae M66-2 fatty acid metabolism regulator YP_002810581.1 1985085 R 579112 CDS YP_002810582.1 227082031 7773092 1986569..1988161 1 NC_012578.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1988161 nhaB 7773092 nhaB Vibrio cholerae M66-2 sodium/proton antiporter YP_002810582.1 1986569 D 579112 CDS YP_002810583.1 227082032 7773093 1988241..1988762 1 NC_012578.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1988762 dsbB 7773093 dsbB Vibrio cholerae M66-2 disulfide bond formation protein B YP_002810583.1 1988241 D 579112 CDS YP_002810584.1 227082033 7773094 complement(1988838..1991720) 1 NC_012578.1 putative cell division protein FtsK 1991720 7773094 VCM66_1827 Vibrio cholerae M66-2 putative cell division protein FtsK YP_002810584.1 1988838 R 579112 CDS YP_002810585.1 227082034 7773095 complement(1991898..1992392) 1 NC_012578.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1992392 lrp 7773095 lrp Vibrio cholerae M66-2 leucine-responsive transcriptional regulator YP_002810585.1 1991898 R 579112 CDS YP_002810586.1 227082035 7773096 1992549..1993673 1 NC_012578.1 alanine dehydrogenase 1993673 ald 7773096 ald Vibrio cholerae M66-2 alanine dehydrogenase YP_002810586.1 1992549 D 579112 CDS YP_002810587.1 227082036 7773097 complement(1993715..1994911) 1 NC_012578.1 hypothetical protein 1994911 7773097 VCM66_1830 Vibrio cholerae M66-2 hypothetical protein YP_002810587.1 1993715 R 579112 CDS YP_002810588.1 227082037 7773098 complement(1994973..1995947) 1 NC_012578.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1995947 cysB 7773098 cysB Vibrio cholerae M66-2 transcriptional regulator CysB YP_002810588.1 1994973 R 579112 CDS YP_002810589.1 227082038 7773099 complement(1996033..1996182) 1 NC_012578.1 hypothetical protein 1996182 7773099 VCM66_1832 Vibrio cholerae M66-2 hypothetical protein YP_002810589.1 1996033 R 579112 CDS YP_002810590.1 227082039 7773100 1996212..1997000 1 NC_012578.1 hypothetical protein 1997000 7773100 VCM66_1833 Vibrio cholerae M66-2 hypothetical protein YP_002810590.1 1996212 D 579112 CDS YP_002810591.1 227082040 7773101 1997062..1997838 1 NC_012578.1 tRNA-(MS[2]IO[6]A)-hydroxylase 1997838 miaE 7773101 miaE Vibrio cholerae M66-2 tRNA-(MS[2]IO[6]A)-hydroxylase YP_002810591.1 1997062 D 579112 CDS YP_002810592.1 227082041 7773102 complement(1997896..1998591) 1 NC_012578.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1998591 pyrF 7773102 pyrF Vibrio cholerae M66-2 orotidine 5'-phosphate decarboxylase YP_002810592.1 1997896 R 579112 CDS YP_002810593.1 227082042 7773103 complement(1998664..1999833) 1 NC_012578.1 hypothetical protein 1999833 7773103 VCM66_1836 Vibrio cholerae M66-2 hypothetical protein YP_002810593.1 1998664 R 579112 CDS YP_002810594.1 227082043 7773104 complement(1999845..2000126) 1 NC_012578.1 hypothetical protein 2000126 7773104 VCM66_1837 Vibrio cholerae M66-2 hypothetical protein YP_002810594.1 1999845 R 579112 CDS YP_002810595.1 227082044 7773105 complement(2000265..2000543) 1 NC_012578.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 2000543 ihfB 7773105 ihfB Vibrio cholerae M66-2 integration host factor subunit beta YP_002810595.1 2000265 R 579112 CDS YP_002810596.1 227082045 7773106 complement(2000831..2002501) 1 NC_012578.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 2002501 rpsA 7773106 rpsA Vibrio cholerae M66-2 30S ribosomal protein S1 YP_002810596.1 2000831 R 579112 CDS YP_002810597.1 227082046 7773107 complement(2002610..2003299) 1 NC_012578.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 2003299 cmk 7773107 cmk Vibrio cholerae M66-2 cytidylate kinase YP_002810597.1 2002610 R 579112 CDS YP_002810598.1 227082047 7773108 complement(2003470..2003781) 1 NC_012578.1 hypothetical protein 2003781 7773108 VCM66_1841 Vibrio cholerae M66-2 hypothetical protein YP_002810598.1 2003470 R 579112 CDS YP_002810599.1 227082048 7773109 complement(2003916..2005775) 1 NC_012578.1 peptidyl-prolyl cis-trans isomerse D 2005775 ppiD 7773109 ppiD Vibrio cholerae M66-2 peptidyl-prolyl cis-trans isomerse D YP_002810599.1 2003916 R 579112 CDS YP_002810600.1 227082049 7773110 complement(2005928..2006200) 1 NC_012578.1 DNA-binding protein HU-beta 2006200 hupB 7773110 hupB Vibrio cholerae M66-2 DNA-binding protein HU-beta YP_002810600.1 2005928 R 579112 CDS YP_002810601.1 227082050 7773111 complement(2006384..2008744) 1 NC_012578.1 ATP-dependent protease LA 2008744 lon 7773111 lon Vibrio cholerae M66-2 ATP-dependent protease LA YP_002810601.1 2006384 R 579112 CDS YP_002810602.1 227082051 7773112 complement(2008867..2010147) 1 NC_012578.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2010147 clpX 7773112 clpX Vibrio cholerae M66-2 ATP-dependent protease ATP-binding subunit ClpX YP_002810602.1 2008867 R 579112 CDS YP_002810603.1 227082052 7773113 complement(2010227..2010829) 1 NC_012578.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2010829 clpP 7773113 clpP Vibrio cholerae M66-2 ATP-dependent Clp protease proteolytic subunit YP_002810603.1 2010227 R 579112 CDS YP_002810604.1 227082053 7773114 complement(2010959..2012260) 1 NC_012578.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2012260 tig 7773114 tig Vibrio cholerae M66-2 trigger factor YP_002810604.1 2010959 R 579112 CDS YP_002810605.1 227082054 7773115 2012367..2012786 1 NC_012578.1 hypothetical protein 2012786 7773115 VCM66_1848 Vibrio cholerae M66-2 hypothetical protein YP_002810605.1 2012367 D 579112 CDS YP_002810606.1 227082055 7773116 2012759..2014552 1 NC_012578.1 putative C4-dicarboxylate transport sensor protein 2014552 dctB 7773116 dctB Vibrio cholerae M66-2 putative C4-dicarboxylate transport sensor protein YP_002810606.1 2012759 D 579112 CDS YP_002810607.1 227082056 7773117 2014555..2015895 1 NC_012578.1 putative C4-dicarboxylate transport transcriptional regulatory protein 2015895 dctD-1 7773117 dctD-1 Vibrio cholerae M66-2 putative C4-dicarboxylate transport transcriptional regulatory protein YP_002810607.1 2014555 D 579112 CDS YP_002810608.1 227082057 7773118 complement(2016011..2017372) 1 NC_012578.1 putative C4-dicarboxylate transport protein 2017372 dctM 7773118 dctM Vibrio cholerae M66-2 putative C4-dicarboxylate transport protein YP_002810608.1 2016011 R 579112 CDS YP_002810609.1 227082058 7773119 complement(2017376..2018074) 1 NC_012578.1 putative C4-dicarboxylate transport protein 2018074 7773119 VCM66_1852 Vibrio cholerae M66-2 putative C4-dicarboxylate transport protein YP_002810609.1 2017376 R 579112 CDS YP_002810610.1 227082059 7773120 complement(2018106..2019104) 1 NC_012578.1 C4-dicarboxylate-binding periplasmic protein 2019104 dctP-2 7773120 dctP-2 Vibrio cholerae M66-2 C4-dicarboxylate-binding periplasmic protein YP_002810610.1 2018106 R 579112 CDS YP_002810611.1 227082060 7773121 complement(2019192..2019287) 1 NC_012578.1 hypothetical protein 2019287 7773121 VCM66_1854 Vibrio cholerae M66-2 hypothetical protein YP_002810611.1 2019192 R 579112 CDS YP_002810612.1 227082061 7773122 complement(2019336..2020862) 1 NC_012578.1 hypothetical protein 2020862 7773122 VCM66_1855 Vibrio cholerae M66-2 hypothetical protein YP_002810612.1 2019336 R 579112 CDS YP_002810613.1 227082062 7773123 complement(2021033..2021203) 1 NC_012578.1 hypothetical protein 2021203 7773123 VCM66_1856 Vibrio cholerae M66-2 hypothetical protein YP_002810613.1 2021033 R 579112 CDS YP_002810614.1 227082063 7773124 2021365..2021835 1 NC_012578.1 hypothetical protein 2021835 7773124 VCM66_1857 Vibrio cholerae M66-2 hypothetical protein YP_002810614.1 2021365 D 579112 CDS YP_002810615.1 227082064 7773125 2021799..2023766 1 NC_012578.1 GGDEF/EAL family protein 2023766 7773125 VCM66_1858 Vibrio cholerae M66-2 GGDEF/EAL family protein YP_002810615.1 2021799 D 579112 CDS YP_002810616.1 227082065 7773126 2023845..2024603 1 NC_012578.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-like protein 2024603 7773126 VCM66_1859 Vibrio cholerae M66-2 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-like protein YP_002810616.1 2023845 D 579112 CDS YP_002810617.1 227082066 7773127 2024606..2025538 1 NC_012578.1 putative phosphatidate cytidylyltransferase 2025538 7773127 VCM66_1860 Vibrio cholerae M66-2 putative phosphatidate cytidylyltransferase YP_002810617.1 2024606 D 579112 CDS YP_002810618.1 227082067 7773128 2025546..2026217 1 NC_012578.1 hypothetical protein 2026217 7773128 VCM66_1861 Vibrio cholerae M66-2 hypothetical protein YP_002810618.1 2025546 D 579112 CDS YP_002810619.1 227082068 7773129 2026307..2026756 1 NC_012578.1 hypothetical protein 2026756 7773129 VCM66_1862 Vibrio cholerae M66-2 hypothetical protein YP_002810619.1 2026307 D 579112 CDS YP_002810620.1 227082069 7773130 2027050..2027670 1 NC_012578.1 hypothetical protein 2027670 7773130 VCM66_1863 Vibrio cholerae M66-2 hypothetical protein YP_002810620.1 2027050 D 579112 CDS YP_002810621.1 227082070 7773131 complement(2027717..2028379) 1 NC_012578.1 hypothetical protein 2028379 7773131 VCM66_1864 Vibrio cholerae M66-2 hypothetical protein YP_002810621.1 2027717 R 579112 CDS YP_002810622.1 227082071 7773132 complement(2028692..2029987) 1 NC_012578.1 hypothetical protein 2029987 7773132 VCM66_1865 Vibrio cholerae M66-2 hypothetical protein YP_002810622.1 2028692 R 579112 CDS YP_002810623.1 227082072 7774002 2030542..2031477 1 NC_012578.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2031477 folD 7774002 folD Vibrio cholerae M66-2 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002810623.1 2030542 D 579112 CDS YP_002810624.1 227082073 7773134 2031452..2031544 1 NC_012578.1 hypothetical protein 2031544 7773134 VCM66_1867 Vibrio cholerae M66-2 hypothetical protein YP_002810624.1 2031452 D 579112 CDS YP_002810625.1 227082074 7773135 2031760..2032623 1 NC_012578.1 PvcB protein 2032623 pvcB 7773135 pvcB Vibrio cholerae M66-2 PvcB protein YP_002810625.1 2031760 D 579112 CDS YP_002810626.1 227082075 7773136 2032608..2034071 1 NC_012578.1 hypothetical protein 2034071 7773136 VCM66_1869 Vibrio cholerae M66-2 hypothetical protein YP_002810626.1 2032608 D 579112 CDS YP_002810627.1 227082076 7773137 complement(2034060..2034167) 1 NC_012578.1 hypothetical protein 2034167 7773137 VCM66_1870 Vibrio cholerae M66-2 hypothetical protein YP_002810627.1 2034060 R 579112 CDS YP_002810628.1 227082077 7773138 complement(2034202..2035131) 1 NC_012578.1 LysR family transcriptional regulator 2035131 7773138 VCM66_1871 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810628.1 2034202 R 579112 CDS YP_002810629.1 227082078 7773139 2035290..2035481 1 NC_012578.1 hypothetical protein 2035481 7773139 VCM66_1872 Vibrio cholerae M66-2 hypothetical protein YP_002810629.1 2035290 D 579112 CDS YP_002810630.1 227082079 7773140 2035451..2037277 1 NC_012578.1 pvcA protein 2037277 pvcA 7773140 pvcA Vibrio cholerae M66-2 pvcA protein YP_002810630.1 2035451 D 579112 CDS YP_002810631.1 227082080 7773141 complement(2037367..2039814) 1 NC_012578.1 biotin sulfoxide reductase 2039814 bisZ 7773141 bisZ Vibrio cholerae M66-2 biotin sulfoxide reductase YP_002810631.1 2037367 R 579112 CDS YP_002810632.1 227082081 7773142 complement(2039837..2040943) 1 NC_012578.1 cytochrome c-type protein YecK 2040943 yecK 7773142 yecK Vibrio cholerae M66-2 cytochrome c-type protein YecK YP_002810632.1 2039837 R 579112 CDS YP_002810633.1 227082082 7773143 complement(2041198..2043738) 1 NC_012578.1 chitinase 2043738 chiA-1 7773143 chiA-1 Vibrio cholerae M66-2 chitinase YP_002810633.1 2041198 R 579112 CDS YP_002810634.1 227082083 7773144 complement(2044002..2045219) 1 NC_012578.1 NupC family protein 2045219 7773144 VCM66_1877 Vibrio cholerae M66-2 NupC family protein YP_002810634.1 2044002 R 579112 CDS YP_002810635.1 227082084 7773145 complement(2045550..2046497) 1 NC_012578.1 LysR family transcriptional regulator 2046497 7773145 VCM66_1879 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810635.1 2045550 R 579112 CDS YP_002810636.1 227082085 7773146 complement(2046661..2047632) 1 NC_012578.1 putative lytic murein transglycosylase 2047632 7773146 VCM66_1880 Vibrio cholerae M66-2 putative lytic murein transglycosylase YP_002810636.1 2046661 R 579112 CDS YP_002810637.1 227082086 7773147 complement(2047657..2047965) 1 NC_012578.1 hypothetical protein 2047965 7773147 VCM66_1881 Vibrio cholerae M66-2 hypothetical protein YP_002810637.1 2047657 R 579112 CDS YP_002810638.1 227082087 7773148 2047996..2048121 1 NC_012578.1 hypothetical protein 2048121 7773148 VCM66_1882 Vibrio cholerae M66-2 hypothetical protein YP_002810638.1 2047996 D 579112 CDS YP_002810639.1 227082088 7773149 2048135..2048797 1 NC_012578.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 2048797 minC 7773149 minC Vibrio cholerae M66-2 septum formation inhibitor YP_002810639.1 2048135 D 579112 CDS YP_002810640.1 227082089 7773150 2048800..2049630 1 NC_012578.1 septum site-determining protein MinD 2049630 minD 7773150 minD Vibrio cholerae M66-2 septum site-determining protein MinD YP_002810640.1 2048800 D 579112 CDS YP_002810641.1 227082090 7773151 2049635..2049898 1 NC_012578.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 2049898 minE 7773151 minE Vibrio cholerae M66-2 cell division topological specificity factor MinE YP_002810641.1 2049635 D 579112 CDS YP_002810642.1 227082091 7773152 2050187..2050678 1 NC_012578.1 lipoprotein 2050678 7773152 VCM66_1886 Vibrio cholerae M66-2 lipoprotein YP_002810642.1 2050187 D 579112 CDS YP_002810643.1 227082092 7773153 complement(2050745..2051242) 1 NC_012578.1 hypothetical protein 2051242 7773153 VCM66_1887 Vibrio cholerae M66-2 hypothetical protein YP_002810643.1 2050745 R 579112 CDS YP_002810644.1 227082093 7773964 2052886..2054766 1 NC_012578.1 hypothetical protein 2054766 7773964 VCM66_1890 Vibrio cholerae M66-2 hypothetical protein YP_002810644.1 2052886 D 579112 CDS YP_002810645.1 227082094 7773155 2054942..2056996 1 NC_012578.1 methyl-accepting chemotaxis protein 2056996 7773155 VCM66_1891 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810645.1 2054942 D 579112 CDS YP_002810646.1 227082095 7773156 complement(2057049..2057594) 1 NC_012578.1 HTH_3 family transcriptional regulator 2057594 7773156 VCM66_1892 Vibrio cholerae M66-2 HTH_3 family transcriptional regulator YP_002810646.1 2057049 R 579112 CDS YP_002810647.1 227082096 7773157 complement(2057606..2057701) 1 NC_012578.1 hypothetical protein 2057701 7773157 VCM66_1893 Vibrio cholerae M66-2 hypothetical protein YP_002810647.1 2057606 R 579112 CDS YP_002810648.1 227082097 7773158 2057682..2058845 1 NC_012578.1 benzoate transport protein 2058845 benE 7773158 benE Vibrio cholerae M66-2 benzoate transport protein YP_002810648.1 2057682 D 579112 CDS YP_002810649.1 227082098 7773159 complement(2058874..2060304) 1 NC_012578.1 O-succinylbenzoic acid--CoA ligase 2060304 menE 7773159 menE Vibrio cholerae M66-2 O-succinylbenzoic acid--CoA ligase YP_002810649.1 2058874 R 579112 CDS YP_002810650.1 227082099 7773160 complement(2060280..2061278) 1 NC_012578.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2061278 menC 7773160 menC Vibrio cholerae M66-2 O-succinylbenzoate synthase YP_002810650.1 2060280 R 579112 CDS YP_002810651.1 227082100 7773161 complement(2061366..2062256) 1 NC_012578.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2062256 menB 7773161 menB Vibrio cholerae M66-2 naphthoate synthase YP_002810651.1 2061366 R 579112 CDS YP_002810652.1 227082101 7773162 complement(2062257..2063048) 1 NC_012578.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 2063048 7773162 VCM66_1898 Vibrio cholerae M66-2 acyl-CoA thioester hydrolase YfbB YP_002810652.1 2062257 R 579112 CDS YP_002810653.1 227082102 7773163 complement(2063038..2064750) 1 NC_012578.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2064750 menD 7773163 menD Vibrio cholerae M66-2 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002810653.1 2063038 R 579112 CDS YP_002810654.1 227082103 7773164 complement(2064747..2066054) 1 NC_012578.1 menaquinone-specific isochorismate synthase 2066054 menF 7773164 menF Vibrio cholerae M66-2 menaquinone-specific isochorismate synthase YP_002810654.1 2064747 R 579112 CDS YP_002810655.1 227082104 7773165 2066269..2067483 1 NC_012578.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2067483 7773165 VCM66_1901 Vibrio cholerae M66-2 aminotransferase AlaT YP_002810655.1 2066269 D 579112 CDS YP_002810656.1 227082105 7773166 2067519..2068220 1 NC_012578.1 hypothetical protein 2068220 7773166 VCM66_1902 Vibrio cholerae M66-2 hypothetical protein YP_002810656.1 2067519 D 579112 CDS YP_002810657.1 227082106 7773167 2068277..2069602 1 NC_012578.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 2069602 dgt 7773167 dgt Vibrio cholerae M66-2 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_002810657.1 2068277 D 579112 CDS YP_002810658.1 227082107 7773168 complement(2069596..2070198) 1 NC_012578.1 hypothetical protein 2070198 7773168 VCM66_1904 Vibrio cholerae M66-2 hypothetical protein YP_002810658.1 2069596 R 579112 CDS YP_002810659.1 227082108 7773169 2070085..2070753 1 NC_012578.1 hypothetical protein 2070753 7773169 VCM66_1905 Vibrio cholerae M66-2 hypothetical protein YP_002810659.1 2070085 D 579112 CDS YP_002810660.1 227082109 7773170 2070710..2070820 1 NC_012578.1 hypothetical protein 2070820 7773170 VCM66_1906 Vibrio cholerae M66-2 hypothetical protein YP_002810660.1 2070710 D 579112 CDS YP_002810661.1 227082110 7773171 complement(2070829..2072676) 1 NC_012578.1 putative peptidase 2072676 7773171 VCM66_1907 Vibrio cholerae M66-2 putative peptidase YP_002810661.1 2070829 R 579112 CDS YP_002810662.1 227082111 7773172 complement(2072889..2074034) 1 NC_012578.1 ribonuclease D 2074034 rnd 7773172 rnd Vibrio cholerae M66-2 ribonuclease D YP_002810662.1 2072889 R 579112 CDS YP_002810663.1 227082112 7773173 complement(2074120..2075820) 1 NC_012578.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2075820 fadD 7773173 fadD Vibrio cholerae M66-2 long-chain-fatty-acid--CoA ligase YP_002810663.1 2074120 R 579112 CDS YP_002810664.1 227082113 7773174 complement(2075945..2076799) 1 NC_012578.1 putative serine hydrolase 2076799 7773174 VCM66_1910 Vibrio cholerae M66-2 putative serine hydrolase YP_002810664.1 2075945 R 579112 CDS YP_002810665.1 227082114 7773175 complement(2076796..2077404) 1 NC_012578.1 putative outer membrane lipoprotein Slp 2077404 7773175 VCM66_1911 Vibrio cholerae M66-2 putative outer membrane lipoprotein Slp YP_002810665.1 2076796 R 579112 CDS YP_002810666.1 227082115 7773176 complement(2077370..2077675) 1 NC_012578.1 hypothetical protein 2077675 7773176 VCM66_1912 Vibrio cholerae M66-2 hypothetical protein YP_002810666.1 2077370 R 579112 CDS YP_002810667.1 227082116 7773177 complement(2077735..2078448) 1 NC_012578.1 hypothetical protein 2078448 7773177 VCM66_1913 Vibrio cholerae M66-2 hypothetical protein YP_002810667.1 2077735 R 579112 CDS YP_002810668.1 227082117 7773178 complement(2078445..2080385) 1 NC_012578.1 ATP-dependent helicase, DinG family 2080385 7773178 VCM66_1914 Vibrio cholerae M66-2 ATP-dependent helicase, DinG family YP_002810668.1 2078445 R 579112 CDS YP_002810669.1 227082118 7773179 2080339..2080776 1 NC_012578.1 hypothetical protein 2080776 7773179 VCM66_1915 Vibrio cholerae M66-2 hypothetical protein YP_002810669.1 2080339 D 579112 CDS YP_002810670.1 227082119 7773180 2080950..2081783 1 NC_012578.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 2081783 purU 7773180 purU Vibrio cholerae M66-2 formyltetrahydrofolate deformylase YP_002810670.1 2080950 D 579112 CDS YP_002810671.1 227082120 7773181 complement(2081857..2083857) 1 NC_012578.1 2,4-dienoyl-CoA reductase 2083857 fadH 7773181 fadH Vibrio cholerae M66-2 2,4-dienoyl-CoA reductase YP_002810671.1 2081857 R 579112 CDS YP_002810672.1 227082121 7773182 2084087..2085937 1 NC_012578.1 protease IV 2085937 sppA 7773182 sppA Vibrio cholerae M66-2 protease IV YP_002810672.1 2084087 D 579112 CDS YP_002810673.1 227082122 7773183 2086054..2087067 1 NC_012578.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2087067 ansA 7773183 ansA Vibrio cholerae M66-2 cytoplasmic asparaginase I YP_002810673.1 2086054 D 579112 CDS YP_002810674.1 227082123 7773184 complement(2087165..2087452) 1 NC_012578.1 hypothetical protein 2087452 7773184 VCM66_1920 Vibrio cholerae M66-2 hypothetical protein YP_002810674.1 2087165 R 579112 CDS YP_002810675.1 227082124 7773185 2087556..2088380 1 NC_012578.1 hypothetical protein 2088380 7773185 VCM66_1921 Vibrio cholerae M66-2 hypothetical protein YP_002810675.1 2087556 D 579112 CDS YP_002810676.1 227082125 7773186 complement(2088541..2088984) 1 NC_012578.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2088984 7773186 VCM66_1922 Vibrio cholerae M66-2 methionine sulfoxide reductase B YP_002810676.1 2088541 R 579112 CDS YP_002810677.1 227082126 7773187 2088990..2089136 1 NC_012578.1 hypothetical protein 2089136 7773187 VCM66_1923 Vibrio cholerae M66-2 hypothetical protein YP_002810677.1 2088990 D 579112 CDS YP_002810678.1 227082127 7773188 2089284..2090279 1 NC_012578.1 glyceraldehyde 3-phosphate dehydrogenase 2090279 gapA-1 7773188 gapA-1 Vibrio cholerae M66-2 glyceraldehyde 3-phosphate dehydrogenase YP_002810678.1 2089284 D 579112 CDS YP_002810679.1 227082128 7773189 2090427..2091317 1 NC_012578.1 hypothetical protein 2091317 7773189 VCM66_1925 Vibrio cholerae M66-2 hypothetical protein YP_002810679.1 2090427 D 579112 CDS YP_002810680.1 227082129 7773190 2091752..2092756 1 NC_012578.1 hypothetical protein 2092756 7773190 VCM66_1926 Vibrio cholerae M66-2 hypothetical protein YP_002810680.1 2091752 D 579112 CDS YP_002810681.1 227082130 7773191 2092893..2093729 1 NC_012578.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2093729 rrmA 7773191 rrmA Vibrio cholerae M66-2 23S rRNA methyltransferase A YP_002810681.1 2092893 D 579112 CDS YP_002810682.1 227082131 7773192 2093750..2094727 1 NC_012578.1 hypothetical protein 2094727 7773192 VCM66_1928 Vibrio cholerae M66-2 hypothetical protein YP_002810682.1 2093750 D 579112 CDS YP_002810683.1 227082132 7773193 2094867..2095223 1 NC_012578.1 hypothetical protein 2095223 7773193 VCM66_1929 Vibrio cholerae M66-2 hypothetical protein YP_002810683.1 2094867 D 579112 CDS YP_002810684.1 227082133 7773194 complement(2095297..2096241) 1 NC_012578.1 chemotaxis protein CheV 2096241 cheV-2 7773194 cheV-2 Vibrio cholerae M66-2 chemotaxis protein CheV YP_002810684.1 2095297 R 579112 CDS YP_002810685.1 227082134 7773195 complement(2096346..2097563) 1 NC_012578.1 ROK family transcriptional regulator 2097563 7773195 VCM66_1931 Vibrio cholerae M66-2 ROK family transcriptional regulator YP_002810685.1 2096346 R 579112 CDS YP_002810686.1 227082135 7773196 2098008..2099453 1 NC_012578.1 pyruvate kinase II 2099453 pykA-1 7773196 pykA-1 Vibrio cholerae M66-2 pyruvate kinase II YP_002810686.1 2098008 D 579112 CDS YP_002810687.1 227082136 7773197 complement(2099495..2100664) 1 NC_012578.1 hypothetical protein 2100664 7773197 VCM66_1933 Vibrio cholerae M66-2 hypothetical protein YP_002810687.1 2099495 R 579112 CDS YP_002810688.1 227082137 7773198 complement(2100671..2100796) 1 NC_012578.1 hypothetical protein 2100796 7773198 VCM66_1934 Vibrio cholerae M66-2 hypothetical protein YP_002810688.1 2100671 R 579112 CDS YP_002810689.1 227082138 7773199 2100896..2101486 1 NC_012578.1 hypothetical protein 2101486 7773199 VCM66_1935 Vibrio cholerae M66-2 hypothetical protein YP_002810689.1 2100896 D 579112 CDS YP_002810690.1 227082139 7773200 2101870..2103453 1 NC_012578.1 sodium-dependent transporter 2103453 7773200 VCM66_1936 Vibrio cholerae M66-2 sodium-dependent transporter YP_002810690.1 2101870 D 579112 CDS YP_002810691.1 227082140 7773201 complement(2103666..2105168) 1 NC_012578.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 2105168 ptsG 7773201 ptsG Vibrio cholerae M66-2 PTS system glucose-specific transporter subunits IIBC YP_002810691.1 2103666 R 579112 CDS YP_002810692.1 227082141 7773202 complement(2105540..2106307) 1 NC_012578.1 Putative deoxyribonuclease 2106307 7773202 VCM66_1938 Vibrio cholerae M66-2 Putative deoxyribonuclease YP_002810692.1 2105540 R 579112 CDS YP_002810693.1 227082142 7773203 complement(2106298..2107272) 1 NC_012578.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 2107272 holB 7773203 holB Vibrio cholerae M66-2 DNA polymerase III subunit delta' YP_002810693.1 2106298 R 579112 CDS YP_002810694.1 227082143 7773204 complement(2107265..2107903) 1 NC_012578.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 2107903 tmk 7773204 tmk Vibrio cholerae M66-2 thymidylate kinase YP_002810694.1 2107265 R 579112 CDS YP_002810695.1 227082144 7773205 complement(2107900..2108916) 1 NC_012578.1 hypothetical protein 2108916 7773205 VCM66_1941 Vibrio cholerae M66-2 hypothetical protein YP_002810695.1 2107900 R 579112 CDS YP_002810696.1 227082145 7773206 complement(2108913..2109746) 1 NC_012578.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 2109746 pabC 7773206 pabC Vibrio cholerae M66-2 4-amino-4-deoxychorismate lyase YP_002810696.1 2108913 R 579112 CDS YP_002810697.1 227082146 7773207 complement(2109794..2111038) 1 NC_012578.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 2111038 fabF 7773207 fabF Vibrio cholerae M66-2 3-oxoacyl-(acyl carrier protein) synthase II YP_002810697.1 2109794 R 579112 CDS YP_002810698.1 227082147 7773208 complement(2111127..2111459) 1 NC_012578.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2111459 acpP 7773208 acpP Vibrio cholerae M66-2 acyl carrier protein YP_002810698.1 2111127 R 579112 CDS YP_002810699.1 227082148 7773209 complement(2111599..2112345) 1 NC_012578.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2112345 fabG 7773209 fabG Vibrio cholerae M66-2 3-ketoacyl-ACP reductase YP_002810699.1 2111599 R 579112 CDS YP_002810700.1 227082149 7773210 complement(2112361..2113299) 1 NC_012578.1 malonyl CoA-acyl carrier protein transacylase 2113299 fabD 7773210 fabD Vibrio cholerae M66-2 malonyl CoA-acyl carrier protein transacylase YP_002810700.1 2112361 R 579112 CDS YP_002810701.1 227082150 7773211 complement(2113354..2114304) 1 NC_012578.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 2114304 fabH-1 7773211 fabH-1 Vibrio cholerae M66-2 3-oxoacyl-(acyl carrier protein) synthase III YP_002810701.1 2113354 R 579112 CDS YP_002810702.1 227082151 7773212 complement(2114310..2115335) 1 NC_012578.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 2115335 plsX 7773212 plsX Vibrio cholerae M66-2 putative glycerol-3-phosphate acyltransferase PlsX YP_002810702.1 2114310 R 579112 CDS YP_002810703.1 227082152 7773213 complement(2115345..2115515) 1 NC_012578.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2115515 rpmF 7773213 rpmF Vibrio cholerae M66-2 50S ribosomal protein L32 YP_002810703.1 2115345 R 579112 CDS YP_002810704.1 227082153 7773214 complement(2115550..2116074) 1 NC_012578.1 hypothetical protein 2116074 7773214 VCM66_1950 Vibrio cholerae M66-2 hypothetical protein YP_002810704.1 2115550 R 579112 CDS YP_002810705.1 227082154 7773215 2116222..2116803 1 NC_012578.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2116803 7773215 VCM66_1951 Vibrio cholerae M66-2 Maf-like protein YP_002810705.1 2116222 D 579112 CDS YP_002810706.1 227082155 7773216 complement(2116904..2117851) 1 NC_012578.1 ribosomal large subunit pseudouridine synthase C 2117851 rluC 7773216 rluC Vibrio cholerae M66-2 ribosomal large subunit pseudouridine synthase C YP_002810706.1 2116904 R 579112 CDS YP_002810707.1 227082156 7773217 2117765..2118004 1 NC_012578.1 hypothetical protein 2118004 7773217 VCM66_1953 Vibrio cholerae M66-2 hypothetical protein YP_002810707.1 2117765 D 579112 CDS YP_002810708.1 227082157 7773218 2118463..2121621 1 NC_012578.1 ribonuclease E 2121621 rne 7773218 rne Vibrio cholerae M66-2 ribonuclease E YP_002810708.1 2118463 D 579112 CDS YP_002810709.1 227082158 7773219 2121969..2123534 1 NC_012578.1 sulfate permease family protein 2123534 7773219 VCM66_1955 Vibrio cholerae M66-2 sulfate permease family protein YP_002810709.1 2121969 D 579112 CDS YP_002810710.1 227082159 7773220 2123652..2124527 1 NC_012578.1 hypothetical protein 2124527 7773220 VCM66_1956 Vibrio cholerae M66-2 hypothetical protein YP_002810710.1 2123652 D 579112 CDS YP_002810711.1 227082160 7773221 complement(2124637..2127321) 1 NC_012578.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2127321 adhE 7773221 adhE Vibrio cholerae M66-2 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002810711.1 2124637 R 579112 CDS YP_002810712.1 227082161 7773222 2127542..2127649 1 NC_012578.1 hypothetical protein 2127649 7773222 VCM66_1958 Vibrio cholerae M66-2 hypothetical protein YP_002810712.1 2127542 D 579112 CDS YP_002810713.1 227082162 7773223 2127948..2128586 1 NC_012578.1 hypothetical protein 2128586 7773223 VCM66_1959 Vibrio cholerae M66-2 hypothetical protein YP_002810713.1 2127948 D 579112 CDS YP_002810714.1 227082163 7773224 complement(2128676..2129788) 1 NC_012578.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 2129788 asd 7773224 asd Vibrio cholerae M66-2 aspartate-semialdehyde dehydrogenase YP_002810714.1 2128676 R 579112 CDS YP_002810715.1 227082164 7773225 2130213..2131658 1 NC_012578.1 Na+/H+ antiporter 2131658 yqkI 7773225 yqkI Vibrio cholerae M66-2 Na+/H+ antiporter YP_002810715.1 2130213 D 579112 CDS YP_002810716.1 227082165 7773226 complement(2131693..2132898) 1 NC_012578.1 Hpt family protein 2132898 7773226 VCM66_1962 Vibrio cholerae M66-2 Hpt family protein YP_002810716.1 2131693 R 579112 CDS YP_002810717.1 227082166 7773227 complement(2133061..2134062) 1 NC_012578.1 nucleoid-associated protein NdpA 2134062 7773227 VCM66_1963 Vibrio cholerae M66-2 nucleoid-associated protein NdpA YP_002810717.1 2133061 R 579112 CDS YP_002810718.1 227082167 7773228 2134147..2134362 1 NC_012578.1 hypothetical protein 2134362 7773228 VCM66_1964 Vibrio cholerae M66-2 hypothetical protein YP_002810718.1 2134147 D 579112 CDS YP_002810719.1 227082168 7773229 2134397..2136199 1 NC_012578.1 putative Inner membrane protein 2136199 7773229 VCM66_1965 Vibrio cholerae M66-2 putative Inner membrane protein YP_002810719.1 2134397 D 579112 CDS YP_002810720.1 227082169 7774066 complement(2136657..2137577) 1 NC_012578.1 histone deacetylase/AcuC/AphA family protein 2137577 7774066 VCM66_1966 Vibrio cholerae M66-2 histone deacetylase/AcuC/AphA family protein YP_002810720.1 2136657 R 579112 CDS YP_002810721.1 227082170 7773231 complement(2137598..2139541) 1 NC_012578.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2139541 topB 7773231 topB Vibrio cholerae M66-2 DNA topoisomerase III YP_002810721.1 2137598 R 579112 CDS YP_002810722.1 227082171 7773232 complement(2139626..2139958) 1 NC_012578.1 putative monothiol glutaredoxin 2139958 7773232 VCM66_1968 Vibrio cholerae M66-2 putative monothiol glutaredoxin YP_002810722.1 2139626 R 579112 CDS YP_002810723.1 227082172 7773233 2140210..2140794 1 NC_012578.1 superoxide dismutase, Fe 2140794 sodB 7773233 sodB Vibrio cholerae M66-2 superoxide dismutase, Fe YP_002810723.1 2140210 D 579112 CDS YP_002810724.1 227082173 7773234 2140876..2141412 1 NC_012578.1 hypothetical protein 2141412 7773234 VCM66_1970 Vibrio cholerae M66-2 hypothetical protein YP_002810724.1 2140876 D 579112 CDS YP_002810725.1 227082174 7773235 2141781..2142461 1 NC_012578.1 short chain dehydrogenase 2142461 7773235 VCM66_1971 Vibrio cholerae M66-2 short chain dehydrogenase YP_002810725.1 2141781 D 579112 CDS YP_002810726.1 227082175 7773236 complement(2142474..2143238) 1 NC_012578.1 vacJ lipoprotein 2143238 vacJ 7773236 vacJ Vibrio cholerae M66-2 vacJ lipoprotein YP_002810726.1 2142474 R 579112 CDS YP_002810727.1 227082176 7773237 complement(2143291..2144505) 1 NC_012578.1 cytochrome c-type biogenesis protein CcmH 2144505 ccmH 7773237 ccmH Vibrio cholerae M66-2 cytochrome c-type biogenesis protein CcmH YP_002810727.1 2143291 R 579112 CDS YP_002810728.1 227082177 7773238 complement(2144508..2144984) 1 NC_012578.1 cytochrome c-type biogenesis protein 2144984 7773238 VCM66_1974 Vibrio cholerae M66-2 cytochrome c-type biogenesis protein YP_002810728.1 2144508 R 579112 CDS YP_002810729.1 227082178 7773239 complement(2144981..2145535) 1 NC_012578.1 thiol:disulfide interchange protein DsbE 2145535 dsbE 7773239 dsbE Vibrio cholerae M66-2 thiol:disulfide interchange protein DsbE YP_002810729.1 2144981 R 579112 CDS YP_002810730.1 227082179 7773240 complement(2145536..2147491) 1 NC_012578.1 cytochrome c-type biogenesis protein CcmF 2147491 ccmF 7773240 ccmF Vibrio cholerae M66-2 cytochrome c-type biogenesis protein CcmF YP_002810730.1 2145536 R 579112 CDS YP_002810731.1 227082180 7773241 complement(2147488..2147970) 1 NC_012578.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2147970 ccmE 7773241 ccmE Vibrio cholerae M66-2 cytochrome c-type biogenesis protein CcmE YP_002810731.1 2147488 R 579112 CDS YP_002810732.1 227082181 7773242 complement(2147967..2148173) 1 NC_012578.1 heme exporter protein D 2148173 ccmD 7773242 ccmD Vibrio cholerae M66-2 heme exporter protein D YP_002810732.1 2147967 R 579112 CDS YP_002810733.1 227082182 7773243 complement(2148173..2148925) 1 NC_012578.1 heme exporter protein C 2148925 ccmC 7773243 ccmC Vibrio cholerae M66-2 heme exporter protein C YP_002810733.1 2148173 R 579112 CDS YP_002810734.1 227082183 7773244 complement(2149016..2149684) 1 NC_012578.1 heme exporter protein B 2149684 ccmB 7773244 ccmB Vibrio cholerae M66-2 heme exporter protein B YP_002810734.1 2149016 R 579112 CDS YP_002810735.1 227082184 7773245 complement(2149681..2150304) 1 NC_012578.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2150304 ccmA 7773245 ccmA Vibrio cholerae M66-2 cytochrome c biogenesis protein CcmA YP_002810735.1 2149681 R 579112 CDS YP_002810736.1 227082185 7773246 complement(2150678..2151181) 1 NC_012578.1 hypothetical protein 2151181 7773246 VCM66_1982 Vibrio cholerae M66-2 hypothetical protein YP_002810736.1 2150678 R 579112 CDS YP_002810737.1 227082186 7773247 complement(2151157..2151681) 1 NC_012578.1 purine-binding chemotaxis protein CheW 2151681 cheW-1 7773247 cheW-1 Vibrio cholerae M66-2 purine-binding chemotaxis protein CheW YP_002810737.1 2151157 R 579112 CDS YP_002810738.1 227082187 7773248 complement(2151690..2152706) 1 NC_012578.1 hypothetical protein 2152706 7773248 VCM66_1984 Vibrio cholerae M66-2 hypothetical protein YP_002810738.1 2151690 R 579112 CDS YP_002810739.1 227082188 7773249 complement(2152699..2153475) 1 NC_012578.1 ParA family protein 2153475 7773249 VCM66_1985 Vibrio cholerae M66-2 ParA family protein YP_002810739.1 2152699 R 579112 CDS YP_002810740.1 227082189 7773250 complement(2153485..2154618) 1 NC_012578.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2154618 cheB-2 7773250 cheB-2 Vibrio cholerae M66-2 chemotaxis-specific methylesterase YP_002810740.1 2153485 R 579112 CDS YP_002810741.1 227082190 7773251 complement(2154645..2157002) 1 NC_012578.1 chemotaxis protein CheA 2157002 cheA-2 7773251 cheA-2 Vibrio cholerae M66-2 chemotaxis protein CheA YP_002810741.1 2154645 R 579112 CDS YP_002810742.1 227082191 7773252 complement(2157012..2157731) 1 NC_012578.1 chemotaxis protein CheZ 2157731 cheZ 7773252 cheZ Vibrio cholerae M66-2 chemotaxis protein CheZ YP_002810742.1 2157012 R 579112 CDS YP_002810743.1 227082192 7773253 complement(2157787..2158179) 1 NC_012578.1 chemotaxis protein CheY 2158179 cheY-3 7773253 cheY-3 Vibrio cholerae M66-2 chemotaxis protein CheY YP_002810743.1 2157787 R 579112 CDS YP_002810744.1 227082193 7773254 complement(2158201..2158935) 1 NC_012578.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2158935 fliA 7773254 fliA Vibrio cholerae M66-2 flagellar biosynthesis sigma factor YP_002810744.1 2158201 R 579112 CDS YP_002810745.1 227082194 7773255 complement(2158928..2159869) 1 NC_012578.1 MinD-like protein 2159869 7773255 VCM66_1991 Vibrio cholerae M66-2 MinD-like protein YP_002810745.1 2158928 R 579112 CDS YP_002810746.1 227082195 7773256 complement(2159829..2161316) 1 NC_012578.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 2161316 flhF 7773256 flhF Vibrio cholerae M66-2 flagellar biosynthesis regulator FlhF YP_002810746.1 2159829 R 579112 CDS YP_002810747.1 227082196 7773257 complement(2161351..2163444) 1 NC_012578.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2163444 flhA 7773257 flhA Vibrio cholerae M66-2 flagellar biosynthesis protein FlhA YP_002810747.1 2161351 R 579112 CDS YP_002810748.1 227082197 7773965 2164243..2164359 1 NC_012578.1 hypothetical protein 2164359 7773965 VCM66_1995 Vibrio cholerae M66-2 hypothetical protein YP_002810748.1 2164243 D 579112 CDS YP_002810749.1 227082198 7773259 2164394..2167213 1 NC_012578.1 peptidase, insulinase family 2167213 7773259 VCM66_1996 Vibrio cholerae M66-2 peptidase, insulinase family YP_002810749.1 2164394 D 579112 CDS YP_002810750.1 227082199 7773260 complement(2167210..2167806) 1 NC_012578.1 hypothetical protein 2167806 7773260 VCM66_1997 Vibrio cholerae M66-2 hypothetical protein YP_002810750.1 2167210 R 579112 CDS YP_002810751.1 227082200 7773261 2167940..2169739 1 NC_012578.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2169739 argS 7773261 argS Vibrio cholerae M66-2 arginyl-tRNA synthetase YP_002810751.1 2167940 D 579112 CDS YP_002810752.1 227082201 7773262 2169830..2170273 1 NC_012578.1 histidine triad family protein 2170273 7773262 VCM66_1999 Vibrio cholerae M66-2 histidine triad family protein YP_002810752.1 2169830 D 579112 CDS YP_002810753.1 227082202 7773263 complement(2170535..2170765) 1 NC_012578.1 hypothetical protein 2170765 feoC 7773263 feoC Vibrio cholerae M66-2 hypothetical protein YP_002810753.1 2170535 R 579112 CDS YP_002810754.1 227082203 7773264 complement(2170762..2173038) 1 NC_012578.1 ferrous iron transport protein B 2173038 feoB 7773264 feoB Vibrio cholerae M66-2 ferrous iron transport protein B YP_002810754.1 2170762 R 579112 CDS YP_002810755.1 227082204 7773265 complement(2173035..2173265) 1 NC_012578.1 ferrous iron transport protein A 2173265 feoA 7773265 feoA Vibrio cholerae M66-2 ferrous iron transport protein A YP_002810755.1 2173035 R 579112 CDS YP_002810756.1 227082205 7773266 2173889..2173996 1 NC_012578.1 hypothetical protein 2173996 7773266 VCM66_2003 Vibrio cholerae M66-2 hypothetical protein YP_002810756.1 2173889 D 579112 CDS YP_002810757.1 227082206 7773267 complement(2174037..2177402) 1 NC_012578.1 AraC family transcriptional regulator 2177402 7773267 VCM66_2004 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002810757.1 2174037 R 579112 CDS YP_002810758.1 227082207 7773268 complement(2177584..2178477) 1 NC_012578.1 zinc ABC transporter periplasmic zinc-binding protein 2178477 znuA 7773268 znuA Vibrio cholerae M66-2 zinc ABC transporter periplasmic zinc-binding protein YP_002810758.1 2177584 R 579112 CDS YP_002810759.1 227082208 7773269 2178552..2179340 1 NC_012578.1 zinc ABC transporter ATP-binding protein 2179340 znuC 7773269 znuC Vibrio cholerae M66-2 zinc ABC transporter ATP-binding protein YP_002810759.1 2178552 D 579112 CDS YP_002810760.1 227082209 7773270 2179333..2180115 1 NC_012578.1 zinc ABC transporter permease 2180115 znuB 7773270 znuB Vibrio cholerae M66-2 zinc ABC transporter permease YP_002810760.1 2179333 D 579112 CDS YP_002810761.1 227082210 7773271 complement(2180222..2181094) 1 NC_012578.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 2181094 sucD 7773271 sucD Vibrio cholerae M66-2 succinyl-CoA synthetase subunit alpha YP_002810761.1 2180222 R 579112 CDS YP_002810762.1 227082211 7773272 complement(2181094..2182260) 1 NC_012578.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 2182260 sucC 7773272 sucC Vibrio cholerae M66-2 succinyl-CoA synthetase subunit beta YP_002810762.1 2181094 R 579112 CDS YP_002810763.1 227082212 7773273 complement(2182428..2183642) 1 NC_012578.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 2183642 sucB 7773273 sucB Vibrio cholerae M66-2 dihydrolipoamide succinyltransferase YP_002810763.1 2182428 R 579112 CDS YP_002810764.1 227082213 7773274 complement(2183671..2186481) 1 NC_012578.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 2186481 sucA 7773274 sucA Vibrio cholerae M66-2 2-oxoglutarate dehydrogenase E1 component YP_002810764.1 2183671 R 579112 CDS YP_002810765.1 227082214 7773275 complement(2186570..2187280) 1 NC_012578.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 2187280 sdhB 7773275 sdhB Vibrio cholerae M66-2 succinate dehydrogenase iron-sulfur subunit YP_002810765.1 2186570 R 579112 CDS YP_002810766.1 227082215 7773276 complement(2187295..2189061) 1 NC_012578.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 2189061 sdhA 7773276 sdhA Vibrio cholerae M66-2 succinate dehydrogenase flavoprotein subunit YP_002810766.1 2187295 R 579112 CDS YP_002810767.1 227082216 7773277 complement(2189062..2189406) 1 NC_012578.1 succinate dehydrogenase, hydrophobic membrane anchor protein 2189406 sdhD 7773277 sdhD Vibrio cholerae M66-2 succinate dehydrogenase, hydrophobic membrane anchor protein YP_002810767.1 2189062 R 579112 CDS YP_002810768.1 227082217 7773278 complement(2189400..2189792) 1 NC_012578.1 succinate dehydrogenase cytochrome b556 large membrane subunit 2189792 sdhC 7773278 sdhC Vibrio cholerae M66-2 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002810768.1 2189400 R 579112 CDS YP_002810769.1 227082218 7773279 2190182..2191477 1 NC_012578.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2191477 gltA 7773279 gltA Vibrio cholerae M66-2 type II citrate synthase YP_002810769.1 2190182 D 579112 CDS YP_002810770.1 227082219 7773280 complement(2191529..2192299) 1 NC_012578.1 hypothetical protein 2192299 7773280 VCM66_2017 Vibrio cholerae M66-2 hypothetical protein YP_002810770.1 2191529 R 579112 CDS YP_002810771.1 227082220 7773281 2192352..2193125 1 NC_012578.1 hypothetical protein 2193125 7773281 VCM66_2018 Vibrio cholerae M66-2 hypothetical protein YP_002810771.1 2192352 D 579112 CDS YP_002810772.1 227082221 7773282 complement(2193175..2194821) 1 NC_012578.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 2194821 pgm 7773282 pgm Vibrio cholerae M66-2 phosphoglucomutase YP_002810772.1 2193175 R 579112 CDS YP_002810773.1 227082222 7773283 complement(2194930..2195463) 1 NC_012578.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 2195463 seqA 7773283 seqA Vibrio cholerae M66-2 replication initiation regulator SeqA YP_002810773.1 2194930 R 579112 CDS YP_002810774.1 227082223 7773284 2195556..2196329 1 NC_012578.1 putative esterase/lipase 2196329 7773284 VCM66_2021 Vibrio cholerae M66-2 putative esterase/lipase YP_002810774.1 2195556 D 579112 CDS YP_002810775.1 227082224 7773285 2196425..2196646 1 NC_012578.1 hypothetical protein 2196646 7773285 VCM66_2022 Vibrio cholerae M66-2 hypothetical protein YP_002810775.1 2196425 D 579112 CDS YP_002810776.1 227082225 7773286 2196695..2197222 1 NC_012578.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2197222 fldA 7773286 fldA Vibrio cholerae M66-2 flavodoxin FldA YP_002810776.1 2196695 D 579112 CDS YP_002810777.1 227082226 7773287 complement(2197296..2197985) 1 NC_012578.1 hypothetical protein 2197985 7773287 VCM66_2024 Vibrio cholerae M66-2 hypothetical protein YP_002810777.1 2197296 R 579112 CDS YP_002810778.1 227082227 7773288 complement(2197991..2198431) 1 NC_012578.1 hypothetical protein 2198431 7773288 VCM66_2025 Vibrio cholerae M66-2 hypothetical protein YP_002810778.1 2197991 R 579112 CDS YP_002810779.1 227082228 7773289 complement(2198394..2198531) 1 NC_012578.1 hypothetical protein 2198531 7773289 VCM66_2026 Vibrio cholerae M66-2 hypothetical protein YP_002810779.1 2198394 R 579112 CDS YP_002810780.1 227082229 7773290 2198547..2199425 1 NC_012578.1 LysR family transcriptional regulator 2199425 7773290 VCM66_2027 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810780.1 2198547 D 579112 CDS YP_002810781.1 227082230 7773291 complement(2199429..2199929) 1 NC_012578.1 hypothetical protein 2199929 7773291 VCM66_2028 Vibrio cholerae M66-2 hypothetical protein YP_002810781.1 2199429 R 579112 CDS YP_002810782.1 227082231 7773292 2200295..2200747 1 NC_012578.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2200747 fur 7773292 fur Vibrio cholerae M66-2 ferric uptake regulator YP_002810782.1 2200295 D 579112 CDS YP_002810783.1 227082232 7773293 complement(2200829..2201845) 1 NC_012578.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 2201845 7773293 VCM66_2030 Vibrio cholerae M66-2 aspartate-semialdehyde dehydrogenase YP_002810783.1 2200829 R 579112 CDS YP_002810784.1 227082233 7773294 complement(2201826..2202989) 1 NC_012578.1 erythronate-4-phosphate dehydrogenase 2202989 pdxB 7773294 pdxB Vibrio cholerae M66-2 erythronate-4-phosphate dehydrogenase YP_002810784.1 2201826 R 579112 CDS YP_002810785.1 227082234 7773295 complement(2203175..2204386) 1 NC_012578.1 3-oxoacyl-ACP synthase I 2204386 fabB 7773295 fabB Vibrio cholerae M66-2 3-oxoacyl-ACP synthase I YP_002810785.1 2203175 R 579112 CDS YP_002810786.1 227082235 7773296 2204504..2206528 1 NC_012578.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2206528 mnmC 7773296 mnmC Vibrio cholerae M66-2 5-methylaminomethyl-2-thiouridine methyltransferase YP_002810786.1 2204504 D 579112 CDS YP_002810787.1 227082236 7773297 complement(2206607..2207134) 1 NC_012578.1 hypothetical protein 2207134 7773297 VCM66_2034 Vibrio cholerae M66-2 hypothetical protein YP_002810787.1 2206607 R 579112 CDS YP_002810788.1 227082237 7773298 complement(2207342..2207605) 1 NC_012578.1 hypothetical protein 2207605 7773298 VCM66_2035 Vibrio cholerae M66-2 hypothetical protein YP_002810788.1 2207342 R 579112 CDS YP_002810789.1 227082238 7773299 complement(2207644..2208174) 1 NC_012578.1 hypothetical protein 2208174 7773299 VCM66_2036 Vibrio cholerae M66-2 hypothetical protein YP_002810789.1 2207644 R 579112 CDS YP_002810790.1 227082239 7773300 complement(2208365..2208481) 1 NC_012578.1 hypothetical protein 2208481 7773300 VCM66_2037 Vibrio cholerae M66-2 hypothetical protein YP_002810790.1 2208365 R 579112 CDS YP_002810791.1 227082240 7773301 2208538..2209161 1 NC_012578.1 hypothetical protein 2209161 7773301 VCM66_2038 Vibrio cholerae M66-2 hypothetical protein YP_002810791.1 2208538 D 579112 CDS YP_002810792.1 227082241 7773302 complement(2209243..2210328) 1 NC_012578.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2210328 aroC 7773302 aroC Vibrio cholerae M66-2 chorismate synthase YP_002810792.1 2209243 R 579112 CDS YP_002810793.1 227082242 7773303 2210426..2210650 1 NC_012578.1 hypothetical protein 2210650 7773303 VCM66_2040 Vibrio cholerae M66-2 hypothetical protein YP_002810793.1 2210426 D 579112 CDS YP_002810794.1 227082243 7773304 complement(2210558..2211502) 1 NC_012578.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2211502 7773304 VCM66_2041 Vibrio cholerae M66-2 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002810794.1 2210558 R 579112 CDS YP_002810795.1 227082244 7773305 2211557..2212117 1 NC_012578.1 hypothetical protein 2212117 7773305 VCM66_2042 Vibrio cholerae M66-2 hypothetical protein YP_002810795.1 2211557 D 579112 CDS YP_002810796.1 227082245 7773306 complement(2212125..2213255) 1 NC_012578.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2213255 flhB 7773306 flhB Vibrio cholerae M66-2 flagellar biosynthesis protein FlhB YP_002810796.1 2212125 R 579112 CDS YP_002810797.1 227082246 7773307 complement(2213265..2214047) 1 NC_012578.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2214047 fliR 7773307 fliR Vibrio cholerae M66-2 flagellar biosynthesis protein FliR YP_002810797.1 2213265 R 579112 CDS YP_002810798.1 227082247 7773308 complement(2214056..2214325) 1 NC_012578.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2214325 fliQ 7773308 fliQ Vibrio cholerae M66-2 flagellar biosynthesis protein FliQ YP_002810798.1 2214056 R 579112 CDS YP_002810799.1 227082248 7773309 complement(2214338..2215237) 1 NC_012578.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2215237 fliP 7773309 fliP Vibrio cholerae M66-2 flagellar biosynthesis protein FliP YP_002810799.1 2214338 R 579112 CDS YP_002810800.1 227082249 7773310 complement(2215215..2215604) 1 NC_012578.1 flagellar protein FliO 2215604 fliO 7773310 fliO Vibrio cholerae M66-2 flagellar protein FliO YP_002810800.1 2215215 R 579112 CDS YP_002810801.1 227082250 7773311 complement(2215608..2216024) 1 NC_012578.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 2216024 fliN 7773311 fliN Vibrio cholerae M66-2 flagellar motor switch protein YP_002810801.1 2215608 R 579112 CDS YP_002810802.1 227082251 7773312 complement(2216089..2217138) 1 NC_012578.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2217138 fliM 7773312 fliM Vibrio cholerae M66-2 flagellar motor switch protein FliM YP_002810802.1 2216089 R 579112 CDS YP_002810803.1 227082252 7773313 complement(2217146..2217649) 1 NC_012578.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2217649 fliL 7773313 fliL Vibrio cholerae M66-2 flagellar basal body-associated protein FliL YP_002810803.1 2217146 R 579112 CDS YP_002810804.1 227082253 7773314 complement(2217684..2219708) 1 NC_012578.1 putative flagellar hook-length control protein FliK 2219708 7773314 VCM66_2051 Vibrio cholerae M66-2 putative flagellar hook-length control protein FliK YP_002810804.1 2217684 R 579112 CDS YP_002810805.1 227082254 7773315 complement(2219872..2220315) 1 NC_012578.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2220315 fliJ 7773315 fliJ Vibrio cholerae M66-2 flagellar biosynthesis chaperone YP_002810805.1 2219872 R 579112 CDS YP_002810806.1 227082255 7773316 complement(2220330..2221649) 1 NC_012578.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2221649 fliI 7773316 fliI Vibrio cholerae M66-2 flagellum-specific ATP synthase YP_002810806.1 2220330 R 579112 CDS YP_002810807.1 227082256 7773317 complement(2221653..2222465) 1 NC_012578.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2222465 fliH 7773317 fliH Vibrio cholerae M66-2 flagellar assembly protein H YP_002810807.1 2221653 R 579112 CDS YP_002810808.1 227082257 7773318 complement(2222546..2223592) 1 NC_012578.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2223592 fliG 7773318 fliG Vibrio cholerae M66-2 flagellar motor switch protein G YP_002810808.1 2222546 R 579112 CDS YP_002810809.1 227082258 7773319 complement(2223585..2225327) 1 NC_012578.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2225327 fliF 7773319 fliF Vibrio cholerae M66-2 flagellar MS-ring protein YP_002810809.1 2223585 R 579112 CDS YP_002810810.1 227082259 7773320 complement(2225343..2225672) 1 NC_012578.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2225672 fliE 7773320 fliE Vibrio cholerae M66-2 flagellar hook-basal body protein FliE YP_002810810.1 2225343 R 579112 CDS YP_002810811.1 227082260 7773321 complement(2225730..2227169) 1 NC_012578.1 flagellar regulatory protein C 2227169 flrC 7773321 flrC Vibrio cholerae M66-2 flagellar regulatory protein C YP_002810811.1 2225730 R 579112 CDS YP_002810812.1 227082261 7773322 complement(2227166..2228221) 1 NC_012578.1 flagellar regulatory protein B 2228221 flrB 7773322 flrB Vibrio cholerae M66-2 flagellar regulatory protein B YP_002810812.1 2227166 R 579112 CDS YP_002810813.1 227082262 7773323 complement(2228333..2229790) 1 NC_012578.1 flagellar regulatory protein A 2229790 flrA 7773323 flrA Vibrio cholerae M66-2 flagellar regulatory protein A YP_002810813.1 2228333 R 579112 CDS YP_002810814.1 227082263 7773324 complement(2230022..2230432) 1 NC_012578.1 flagellin specific chaperone; flagellar protein FliS 2230432 fliS 7773324 fliS Vibrio cholerae M66-2 flagellar protein FliS YP_002810814.1 2230022 R 579112 CDS YP_002810815.1 227082264 7773325 complement(2230443..2230757) 1 NC_012578.1 putative flagellar rod protein FlaI 2230757 7773325 VCM66_2062 Vibrio cholerae M66-2 putative flagellar rod protein FlaI YP_002810815.1 2230443 R 579112 CDS YP_002810816.1 227082265 7773326 complement(2230750..2232750) 1 NC_012578.1 involved in flagellin assembly; flagellar capping protein 2232750 fliD 7773326 fliD Vibrio cholerae M66-2 flagellar capping protein YP_002810816.1 2230750 R 579112 CDS YP_002810817.1 227082266 7773327 complement(2232772..2233233) 1 NC_012578.1 possibly involved in flagella export; flagellar protein FlaG 2233233 flaG 7773327 flaG Vibrio cholerae M66-2 flagellar protein FlaG YP_002810817.1 2232772 R 579112 CDS YP_002810818.1 227082267 7773328 complement(2233307..2234437) 1 NC_012578.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin 2234437 flaB 7773328 flaB Vibrio cholerae M66-2 flagellin YP_002810818.1 2233307 R 579112 CDS YP_002810819.1 227082268 7773329 complement(2234673..2235806) 1 NC_012578.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin 2235806 flaD 7773329 flaD Vibrio cholerae M66-2 flagellin YP_002810819.1 2234673 R 579112 CDS YP_002810820.1 227082269 7773330 complement(2236096..2237232) 1 NC_012578.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin 2237232 flaE 7773330 flaE Vibrio cholerae M66-2 flagellin YP_002810820.1 2236096 R 579112 CDS YP_002810821.1 227082270 7773331 complement(2237356..2238264) 1 NC_012578.1 tyrA protein 2238264 7773331 VCM66_2068 Vibrio cholerae M66-2 tyrA protein YP_002810821.1 2237356 R 579112 CDS YP_002810822.1 227082271 7773332 complement(2238330..2238794) 1 NC_012578.1 hypothetical protein 2238794 7773332 VCM66_2069 Vibrio cholerae M66-2 hypothetical protein YP_002810822.1 2238330 R 579112 CDS YP_002810823.1 227082272 7773333 2238938..2239294 1 NC_012578.1 hypothetical protein 2239294 7773333 VCM66_2070 Vibrio cholerae M66-2 hypothetical protein YP_002810823.1 2238938 D 579112 CDS YP_002810824.1 227082273 7773334 complement(2239270..2239368) 1 NC_012578.1 hypothetical protein 2239368 7773334 VCM66_2071 Vibrio cholerae M66-2 hypothetical protein YP_002810824.1 2239270 R 579112 CDS YP_002810825.1 227082274 7773335 complement(2239361..2239648) 1 NC_012578.1 hypothetical protein 2239648 7773335 VCM66_2072 Vibrio cholerae M66-2 hypothetical protein YP_002810825.1 2239361 R 579112 CDS YP_002810826.1 227082275 7773336 2239851..2240246 1 NC_012578.1 hypothetical protein 2240246 7773336 VCM66_2073 Vibrio cholerae M66-2 hypothetical protein YP_002810826.1 2239851 D 579112 CDS YP_002810827.1 227082276 7773337 complement(2240212..2240307) 1 NC_012578.1 hypothetical protein 2240307 7773337 VCM66_2074 Vibrio cholerae M66-2 hypothetical protein YP_002810827.1 2240212 R 579112 CDS YP_002810828.1 227082277 7773338 2240277..2241410 1 NC_012578.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2241410 dapE 7773338 dapE Vibrio cholerae M66-2 succinyl-diaminopimelate desuccinylase YP_002810828.1 2240277 D 579112 CDS YP_002810829.1 227082278 7773339 2241338..2242087 1 NC_012578.1 D,D-carboxypeptidase-like protein 2242087 7773339 VCM66_2076 Vibrio cholerae M66-2 D,D-carboxypeptidase-like protein YP_002810829.1 2241338 D 579112 CDS YP_002810830.1 227082279 7773340 2242077..2242301 1 NC_012578.1 hypothetical protein 2242301 7773340 VCM66_2077 Vibrio cholerae M66-2 hypothetical protein YP_002810830.1 2242077 D 579112 CDS YP_002810831.1 227082280 7773341 complement(2242285..2242380) 1 NC_012578.1 hypothetical protein 2242380 7773341 VCM66_2078 Vibrio cholerae M66-2 hypothetical protein YP_002810831.1 2242285 R 579112 CDS YP_002810832.1 227082281 7773342 complement(2242394..2243413) 1 NC_012578.1 lipoprotein 2243413 nlpB 7773342 nlpB Vibrio cholerae M66-2 lipoprotein YP_002810832.1 2242394 R 579112 CDS YP_002810833.1 227082282 7773343 complement(2243471..2244349) 1 NC_012578.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2244349 dapA 7773343 dapA Vibrio cholerae M66-2 dihydrodipicolinate synthase YP_002810833.1 2243471 R 579112 CDS YP_002810834.1 227082283 7773344 2244513..2244617 1 NC_012578.1 hypothetical protein 2244617 7773344 VCM66_2081 Vibrio cholerae M66-2 hypothetical protein YP_002810834.1 2244513 D 579112 CDS YP_002810835.1 227082284 7773345 2244627..2245169 1 NC_012578.1 putative glycine cleavage system transcriptional repressor 2245169 7773345 VCM66_2082 Vibrio cholerae M66-2 putative glycine cleavage system transcriptional repressor YP_002810835.1 2244627 D 579112 CDS YP_002810836.1 227082285 7773346 2245184..2245651 1 NC_012578.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2245651 bcp 7773346 bcp Vibrio cholerae M66-2 thioredoxin-dependent thiol peroxidase YP_002810836.1 2245184 D 579112 CDS YP_002810837.1 227082286 7773347 complement(2245753..2247624) 1 NC_012578.1 methyl-accepting chemotaxis protein 2247624 7773347 VCM66_2084 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002810837.1 2245753 R 579112 CDS YP_002810838.1 227082287 7773348 complement(2247815..2248879) 1 NC_012578.1 putative permease PerM 2248879 7773348 VCM66_2085 Vibrio cholerae M66-2 putative permease PerM YP_002810838.1 2247815 R 579112 CDS YP_002810839.1 227082288 7773349 complement(2248872..2249108) 1 NC_012578.1 hypothetical protein 2249108 7773349 VCM66_2086 Vibrio cholerae M66-2 hypothetical protein YP_002810839.1 2248872 R 579112 CDS YP_002810840.1 227082289 7773350 2249292..2250746 1 NC_012578.1 hypothetical protein 2250746 7773350 VCM66_2087 Vibrio cholerae M66-2 hypothetical protein YP_002810840.1 2249292 D 579112 CDS YP_002810841.1 227082290 7773351 2250769..2251119 1 NC_012578.1 arsenate reductase 2251119 arsC 7773351 arsC Vibrio cholerae M66-2 arsenate reductase YP_002810841.1 2250769 D 579112 CDS YP_002810842.1 227082291 7773352 2251116..2251676 1 NC_012578.1 Trp repressor-binding protein 2251676 wrbA 7773352 wrbA Vibrio cholerae M66-2 Trp repressor-binding protein YP_002810842.1 2251116 D 579112 CDS YP_002810843.1 227082292 7773353 2251679..2252116 1 NC_012578.1 hypothetical protein 2252116 7773353 VCM66_2090 Vibrio cholerae M66-2 hypothetical protein YP_002810843.1 2251679 D 579112 CDS YP_002810844.1 227082293 7773354 complement(2252323..2253471) 1 NC_012578.1 hypothetical protein 2253471 7773354 VCM66_2091 Vibrio cholerae M66-2 hypothetical protein YP_002810844.1 2252323 R 579112 CDS YP_002810845.1 227082294 7773355 complement(2253525..2253635) 1 NC_012578.1 hypothetical protein 2253635 7773355 VCM66_2092 Vibrio cholerae M66-2 hypothetical protein YP_002810845.1 2253525 R 579112 CDS YP_002810846.1 227082295 7773356 complement(2253608..2253718) 1 NC_012578.1 hypothetical protein 2253718 7773356 VCM66_2093 Vibrio cholerae M66-2 hypothetical protein YP_002810846.1 2253608 R 579112 CDS YP_002810847.1 227082296 7773357 2253692..2254945 1 NC_012578.1 uracil permease 2254945 uraA 7773357 uraA Vibrio cholerae M66-2 uracil permease YP_002810847.1 2253692 D 579112 CDS YP_002810848.1 227082297 7773358 complement(2255016..2255498) 1 NC_012578.1 hypothetical protein 2255498 7773358 VCM66_2095 Vibrio cholerae M66-2 hypothetical protein YP_002810848.1 2255016 R 579112 CDS YP_002810849.1 227082298 7773359 complement(2255512..2255625) 1 NC_012578.1 hypothetical protein 2255625 7773359 VCM66_2096 Vibrio cholerae M66-2 hypothetical protein YP_002810849.1 2255512 R 579112 CDS YP_002810850.1 227082299 7773360 complement(2255632..2257293) 1 NC_012578.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase 2257293 ushA 7773360 ushA Vibrio cholerae M66-2 bifunctional UDP-sugar hydrolase/5'-nucleotidase YP_002810850.1 2255632 R 579112 CDS YP_002810851.1 227082300 7773361 complement(2257835..2258686) 1 NC_012578.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 2258686 kdsA 7773361 kdsA Vibrio cholerae M66-2 2-dehydro-3-deoxyphosphooctonate aldolase YP_002810851.1 2257835 R 579112 CDS YP_002810852.1 227082301 7773362 complement(2258706..2259518) 1 NC_012578.1 hypothetical protein 2259518 7773362 VCM66_2099 Vibrio cholerae M66-2 hypothetical protein YP_002810852.1 2258706 R 579112 CDS YP_002810853.1 227082302 7773363 complement(2259534..2259917) 1 NC_012578.1 hypothetical protein 2259917 7773363 VCM66_2100 Vibrio cholerae M66-2 hypothetical protein YP_002810853.1 2259534 R 579112 CDS YP_002810854.1 227082303 7773364 complement(2259917..2260777) 1 NC_012578.1 hemK protein 2260777 hemK 7773364 hemK Vibrio cholerae M66-2 hemK protein YP_002810854.1 2259917 R 579112 CDS YP_002810855.1 227082304 7773365 complement(2260781..2261869) 1 NC_012578.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2261869 prfA 7773365 prfA Vibrio cholerae M66-2 peptide chain release factor 1 YP_002810855.1 2260781 R 579112 CDS YP_002810856.1 227082305 7773366 complement(2261899..2263158) 1 NC_012578.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2263158 hemA 7773366 hemA Vibrio cholerae M66-2 glutamyl-tRNA reductase YP_002810856.1 2261899 R 579112 CDS YP_002810857.1 227082306 7773367 2263299..2263934 1 NC_012578.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 2263934 lolB 7773367 lolB Vibrio cholerae M66-2 outer membrane lipoprotein LolB YP_002810857.1 2263299 D 579112 CDS YP_002810858.1 227082307 7773368 2263916..2264803 1 NC_012578.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2264803 ipk 7773368 ipk Vibrio cholerae M66-2 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002810858.1 2263916 D 579112 CDS YP_002810859.1 227082308 7773369 2264834..2265778 1 NC_012578.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2265778 prsA 7773369 prsA Vibrio cholerae M66-2 ribose-phosphate pyrophosphokinase YP_002810859.1 2264834 D 579112 CDS YP_002810860.1 227082309 7773370 2265947..2266537 1 NC_012578.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2266537 pth 7773370 pth Vibrio cholerae M66-2 peptidyl-tRNA hydrolase YP_002810860.1 2265947 D 579112 CDS YP_002810861.1 227082310 7773371 2266488..2267639 1 NC_012578.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2267639 7773371 VCM66_2108 Vibrio cholerae M66-2 GTP-dependent nucleic acid-binding protein EngD YP_002810861.1 2266488 D 579112 CDS YP_002810862.1 227082311 7774042 complement(2269979..2271112) 1 NC_012578.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin 2271112 flaC 7774042 flaC Vibrio cholerae M66-2 flagellin YP_002810862.1 2269979 R 579112 CDS YP_002810863.1 227082312 7773373 complement(2271667..2272806) 1 NC_012578.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin 2272806 flaA 7773373 flaA Vibrio cholerae M66-2 flagellin YP_002810863.1 2271667 R 579112 CDS YP_002810864.1 227082313 7773374 complement(2272955..2273134) 1 NC_012578.1 hypothetical protein 2273134 7773374 VCM66_2112 Vibrio cholerae M66-2 hypothetical protein YP_002810864.1 2272955 R 579112 CDS YP_002810865.1 227082314 7773375 complement(2273214..2274407) 1 NC_012578.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes.; flagellar hook-associated protein FlgL 2274407 flgL 7773375 flgL Vibrio cholerae M66-2 flagellar hook-associated protein FlgL YP_002810865.1 2273214 R 579112 CDS YP_002810866.1 227082315 7773376 complement(2274420..2276294) 1 NC_012578.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 2276294 flgK 7773376 flgK Vibrio cholerae M66-2 flagellar hook-associated protein FlgK YP_002810866.1 2274420 R 579112 CDS YP_002810867.1 227082316 7773377 complement(2276474..2277412) 1 NC_012578.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 2277412 flgJ 7773377 flgJ Vibrio cholerae M66-2 flagellar rod assembly protein/muramidase FlgJ YP_002810867.1 2276474 R 579112 CDS YP_002810868.1 227082317 7773378 complement(2277423..2278508) 1 NC_012578.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 2278508 flgI 7773378 flgI Vibrio cholerae M66-2 flagellar basal body P-ring protein YP_002810868.1 2277423 R 579112 CDS YP_002810869.1 227082318 7773379 complement(2278599..2279384) 1 NC_012578.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 2279384 flgH 7773379 flgH Vibrio cholerae M66-2 flagellar basal body L-ring protein YP_002810869.1 2278599 R 579112 CDS YP_002810870.1 227082319 7773380 complement(2279399..2280187) 1 NC_012578.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 2280187 flgG 7773380 flgG Vibrio cholerae M66-2 flagellar basal body rod protein FlgG YP_002810870.1 2279399 R 579112 CDS YP_002810871.1 227082320 7773381 complement(2280207..2280956) 1 NC_012578.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 2280956 flgF 7773381 flgF Vibrio cholerae M66-2 flagellar basal body rod protein FlgF YP_002810871.1 2280207 R 579112 CDS YP_002810872.1 227082321 7773382 complement(2281139..2282443) 1 NC_012578.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 2282443 flgE 7773382 flgE Vibrio cholerae M66-2 flagellar hook protein FlgE YP_002810872.1 2281139 R 579112 CDS YP_002810873.1 227082322 7773383 complement(2282472..2283179) 1 NC_012578.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 2283179 flgD 7773383 flgD Vibrio cholerae M66-2 flagellar basal body rod modification protein YP_002810873.1 2282472 R 579112 CDS YP_002810874.1 227082323 7773384 complement(2283197..2283613) 1 NC_012578.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 2283613 flgC 7773384 flgC Vibrio cholerae M66-2 flagellar basal body rod protein FlgC YP_002810874.1 2283197 R 579112 CDS YP_002810875.1 227082324 7773385 complement(2283618..2284013) 1 NC_012578.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 2284013 flgB 7773385 flgB Vibrio cholerae M66-2 flagellar basal body rod protein FlgB YP_002810875.1 2283618 R 579112 CDS YP_002810876.1 227082325 7773386 complement(2284233..2285060) 1 NC_012578.1 chemotaxis protein methyltransferase CheR 2285060 cheR-2 7773386 cheR-2 Vibrio cholerae M66-2 chemotaxis protein methyltransferase CheR YP_002810876.1 2284233 R 579112 CDS YP_002810877.1 227082326 7773387 complement(2285071..2285997) 1 NC_012578.1 chemotaxis protein CheV 2285997 cheV-3 7773387 cheV-3 Vibrio cholerae M66-2 chemotaxis protein CheV YP_002810877.1 2285071 R 579112 CDS YP_002810878.1 227082327 7773388 2286054..2286821 1 NC_012578.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2286821 flgA 7773388 flgA Vibrio cholerae M66-2 flagellar basal body P-ring biosynthesis protein FlgA YP_002810878.1 2286054 D 579112 CDS YP_002810879.1 227082328 7773389 2286952..2287275 1 NC_012578.1 putative negative regulator of flagellin synthesis FlgM 2287275 7773389 VCM66_2127 Vibrio cholerae M66-2 putative negative regulator of flagellin synthesis FlgM YP_002810879.1 2286952 D 579112 CDS YP_002810880.1 227082329 7773390 2287373..2287804 1 NC_012578.1 hypothetical protein 2287804 7773390 VCM66_2128 Vibrio cholerae M66-2 hypothetical protein YP_002810880.1 2287373 D 579112 CDS YP_002810881.1 227082330 7773391 complement(2287914..2288351) 1 NC_012578.1 hypothetical protein 2288351 7773391 VCM66_2129 Vibrio cholerae M66-2 hypothetical protein YP_002810881.1 2287914 R 579112 CDS YP_002810882.1 227082331 7773392 complement(2288359..2289027) 1 NC_012578.1 hypothetical protein 2289027 7773392 VCM66_2130 Vibrio cholerae M66-2 hypothetical protein YP_002810882.1 2288359 R 579112 CDS YP_002810883.1 227082332 7773393 2289155..2290288 1 NC_012578.1 hypothetical protein 2290288 7773393 VCM66_2131 Vibrio cholerae M66-2 hypothetical protein YP_002810883.1 2289155 D 579112 CDS YP_002810884.1 227082333 7773394 complement(2290418..2297659) 1 NC_012578.1 nonribosomal peptide synthetase VibF 2297659 vibF 7773394 vibF Vibrio cholerae M66-2 nonribosomal peptide synthetase VibF YP_002810884.1 2290418 R 579112 CDS YP_002810885.1 227082334 7773395 complement(2297917..2298732) 1 NC_012578.1 vibriobactin utilization protein ViuB 2298732 viuB 7773395 viuB Vibrio cholerae M66-2 vibriobactin utilization protein ViuB YP_002810885.1 2297917 R 579112 CDS YP_002810886.1 227082335 7773396 complement(2299036..2301099) 1 NC_012578.1 ferric vibriobactin receptor 2301099 viuA 7773396 viuA Vibrio cholerae M66-2 ferric vibriobactin receptor YP_002810886.1 2299036 R 579112 CDS YP_002810887.1 227082336 7773397 2301519..2302217 1 NC_012578.1 hypothetical protein 2302217 7773397 VCM66_2135 Vibrio cholerae M66-2 hypothetical protein YP_002810887.1 2301519 D 579112 CDS YP_002810888.1 227082337 7773398 complement(2302306..2303271) 1 NC_012578.1 outer membrane protein OmpA 2303271 ompA 7773398 ompA Vibrio cholerae M66-2 outer membrane protein OmpA YP_002810888.1 2302306 R 579112 CDS YP_002810889.1 227082338 7773399 complement(2303567..2305096) 1 NC_012578.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2305096 gltX 7773399 gltX Vibrio cholerae M66-2 glutamyl-tRNA synthetase YP_002810889.1 2303567 R 579112 CDS YP_002810890.1 227082339 7773400 2305165..2307912 1 NC_012578.1 cation transport ATPase, E1-E2 family 2307912 7773400 VCM66_2138 Vibrio cholerae M66-2 cation transport ATPase, E1-E2 family YP_002810890.1 2305165 D 579112 CDS YP_002810891.1 227082340 7773401 2307909..2308361 1 NC_012578.1 hypothetical protein 2308361 7773401 VCM66_2139 Vibrio cholerae M66-2 hypothetical protein YP_002810891.1 2307909 D 579112 CDS YP_002810892.1 227082341 7773402 complement(2308498..2311149) 1 NC_012578.1 beta-N-acetylhexosaminidase 2311149 chb-2 7773402 chb-2 Vibrio cholerae M66-2 beta-N-acetylhexosaminidase YP_002810892.1 2308498 R 579112 CDS YP_002810893.1 227082342 7773403 2311182..2311295 1 NC_012578.1 hypothetical protein 2311295 7773403 VCM66_2141 Vibrio cholerae M66-2 hypothetical protein YP_002810893.1 2311182 D 579112 CDS YP_002810894.1 227082343 7773404 complement(2311377..2311493) 1 NC_012578.1 hypothetical protein 2311493 7773404 VCM66_2142 Vibrio cholerae M66-2 hypothetical protein YP_002810894.1 2311377 R 579112 CDS YP_002810895.1 227082344 7773405 2311566..2312462 1 NC_012578.1 hypothetical protein 2312462 7773405 VCM66_2143 Vibrio cholerae M66-2 hypothetical protein YP_002810895.1 2311566 D 579112 CDS YP_002810896.1 227082345 7774061 2312943..2313083 1 NC_012578.1 hypothetical protein 2313083 7774061 VCM66_2144 Vibrio cholerae M66-2 hypothetical protein YP_002810896.1 2312943 D 579112 CDS YP_002810897.1 227082346 7773407 2313265..2313843 1 NC_012578.1 hypothetical protein 2313843 7773407 VCM66_2145 Vibrio cholerae M66-2 hypothetical protein YP_002810897.1 2313265 D 579112 CDS YP_002810898.1 227082347 7773408 2313873..2314895 1 NC_012578.1 pseudouridine synthase family 1 protein 2314895 7773408 VCM66_2146 Vibrio cholerae M66-2 pseudouridine synthase family 1 protein YP_002810898.1 2313873 D 579112 CDS YP_002810899.1 227082348 7773409 complement(2314993..2316531) 1 NC_012578.1 GGDEF family protein 2316531 7773409 VCM66_2147 Vibrio cholerae M66-2 GGDEF family protein YP_002810899.1 2314993 R 579112 CDS YP_002810900.1 227082349 7773410 complement(2316762..2317388) 1 NC_012578.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2317388 upp 7773410 upp Vibrio cholerae M66-2 uracil phosphoribosyltransferase YP_002810900.1 2316762 R 579112 CDS YP_002810901.1 227082350 7773411 2317555..2318595 1 NC_012578.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2318595 purM 7773411 purM Vibrio cholerae M66-2 phosphoribosylaminoimidazole synthetase YP_002810901.1 2317555 D 579112 CDS YP_002810902.1 227082351 7773412 2318598..2319236 1 NC_012578.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2319236 purN 7773412 purN Vibrio cholerae M66-2 phosphoribosylglycinamide formyltransferase YP_002810902.1 2318598 D 579112 CDS YP_002810903.1 227082352 7773413 2319255..2319362 1 NC_012578.1 hypothetical protein 2319362 7773413 VCM66_2151 Vibrio cholerae M66-2 hypothetical protein YP_002810903.1 2319255 D 579112 CDS YP_002810904.1 227082353 7773414 complement(2319377..2320222) 1 NC_012578.1 hypothetical protein 2320222 7773414 VCM66_2152 Vibrio cholerae M66-2 hypothetical protein YP_002810904.1 2319377 R 579112 CDS YP_002810905.1 227082354 7773415 complement(2320285..2320860) 1 NC_012578.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2320860 gmhA 7773415 gmhA Vibrio cholerae M66-2 phosphoheptose isomerase YP_002810905.1 2320285 R 579112 CDS YP_002810906.1 227082355 7773416 2321178..2323622 1 NC_012578.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 2323622 fadE 7773416 fadE Vibrio cholerae M66-2 acyl-CoA dehydrogenase YP_002810906.1 2321178 D 579112 CDS YP_002810907.1 227082356 7773417 complement(2323769..2325028) 1 NC_012578.1 hypothetical protein 2325028 7773417 VCM66_2155 Vibrio cholerae M66-2 hypothetical protein YP_002810907.1 2323769 R 579112 CDS YP_002810908.1 227082357 7773418 complement(2325037..2325780) 1 NC_012578.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 2325780 dnaQ 7773418 dnaQ Vibrio cholerae M66-2 DNA polymerase III subunit epsilon YP_002810908.1 2325037 R 579112 CDS YP_002810909.1 227082358 7773419 2325837..2326307 1 NC_012578.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 2326307 rnhA 7773419 rnhA Vibrio cholerae M66-2 ribonuclease H YP_002810909.1 2325837 D 579112 CDS YP_002810910.1 227082359 7773420 complement(2326378..2327115) 1 NC_012578.1 hypothetical protein 2327115 7773420 VCM66_2158 Vibrio cholerae M66-2 hypothetical protein YP_002810910.1 2326378 R 579112 CDS YP_002810911.1 227082360 7773421 2327153..2327911 1 NC_012578.1 putative hydroxyacylglutathione hydrolase GloB 2327911 7773421 VCM66_2159 Vibrio cholerae M66-2 putative hydroxyacylglutathione hydrolase GloB YP_002810911.1 2327153 D 579112 CDS YP_002810912.1 227082361 7773422 2327983..2329581 1 NC_012578.1 membrane-bound lytic murein transglycosylase D 2329581 mltD 7773422 mltD Vibrio cholerae M66-2 membrane-bound lytic murein transglycosylase D YP_002810912.1 2327983 D 579112 CDS YP_002810913.1 227082362 7773423 complement(2329598..2330443) 1 NC_012578.1 hypothetical protein 2330443 7773423 VCM66_2161 Vibrio cholerae M66-2 hypothetical protein YP_002810913.1 2329598 R 579112 CDS YP_002810914.1 227082363 7773424 complement(2330511..2330855) 1 NC_012578.1 nitrogen regulatory protein P-II 2330855 glnB-2 7773424 glnB-2 Vibrio cholerae M66-2 nitrogen regulatory protein P-II YP_002810914.1 2330511 R 579112 CDS YP_002810915.1 227082364 7773425 complement(2331009..2331533) 1 NC_012578.1 decarboxylase 2331533 7773425 VCM66_2163 Vibrio cholerae M66-2 decarboxylase YP_002810915.1 2331009 R 579112 CDS YP_002810916.1 227082365 7773426 complement(2331910..2332233) 1 NC_012578.1 cytochrome c554 2332233 7773426 VCM66_2164 Vibrio cholerae M66-2 cytochrome c554 YP_002810916.1 2331910 R 579112 CDS YP_002810917.1 227082366 7773427 complement(2332269..2333591) 1 NC_012578.1 tRNA(Ile)-lysidine synthetase 2333591 tilS 7773427 tilS Vibrio cholerae M66-2 tRNA(Ile)-lysidine synthetase YP_002810917.1 2332269 R 579112 CDS YP_002810918.1 227082367 7773428 2333559..2333663 1 NC_012578.1 hypothetical protein 2333663 7773428 VCM66_2166 Vibrio cholerae M66-2 hypothetical protein YP_002810918.1 2333559 D 579112 CDS YP_002810919.1 227082368 7773429 complement(2333731..2334690) 1 NC_012578.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 2334690 accA 7773429 accA Vibrio cholerae M66-2 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002810919.1 2333731 R 579112 CDS YP_002810920.1 227082369 7773430 complement(2334745..2338239) 1 NC_012578.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 2338239 dnaE 7773430 dnaE Vibrio cholerae M66-2 DNA polymerase III subunit alpha YP_002810920.1 2334745 R 579112 CDS YP_002810921.1 227082370 7773431 complement(2338263..2338883) 1 NC_012578.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 2338883 rnhB 7773431 rnhB Vibrio cholerae M66-2 ribonuclease HII YP_002810921.1 2338263 R 579112 CDS YP_002810922.1 227082371 7773432 complement(2338908..2340047) 1 NC_012578.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 2340047 lpxB 7773432 lpxB Vibrio cholerae M66-2 lipid-A-disaccharide synthase YP_002810922.1 2338908 R 579112 CDS YP_002810923.1 227082372 7773433 complement(2340208..2340996) 1 NC_012578.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 2340996 lpxA 7773433 lpxA Vibrio cholerae M66-2 UDP-N-acetylglucosamine acyltransferase YP_002810923.1 2340208 R 579112 CDS YP_002810924.1 227082373 7773434 complement(2340998..2341459) 1 NC_012578.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 2341459 fabZ 7773434 fabZ Vibrio cholerae M66-2 (3R)-hydroxymyristoyl-ACP dehydratase YP_002810924.1 2340998 R 579112 CDS YP_002810925.1 227082374 7773435 complement(2341535..2342590) 1 NC_012578.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 2342590 lpxD 7773435 lpxD Vibrio cholerae M66-2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002810925.1 2341535 R 579112 CDS YP_002810926.1 227082375 7773436 complement(2342600..2343109) 1 NC_012578.1 outer membrane protein OmpH 2343109 ompH 7773436 ompH Vibrio cholerae M66-2 outer membrane protein OmpH YP_002810926.1 2342600 R 579112 CDS YP_002810927.1 227082376 7773437 complement(2343124..2345535) 1 NC_012578.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 2345535 7773437 VCM66_2175 Vibrio cholerae M66-2 outer membrane protein assembly factor YaeT YP_002810927.1 2343124 R 579112 CDS YP_002810928.1 227082377 7773438 complement(2345584..2346942) 1 NC_012578.1 hypothetical protein 2346942 7773438 VCM66_2176 Vibrio cholerae M66-2 hypothetical protein YP_002810928.1 2345584 R 579112 CDS YP_002810929.1 227082378 7773439 complement(2346939..2348147) 1 NC_012578.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2348147 dxr 7773439 dxr Vibrio cholerae M66-2 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002810929.1 2346939 R 579112 CDS YP_002810930.1 227082379 7773440 complement(2348196..2349038) 1 NC_012578.1 phosphatidate cytidylyltransferase 2349038 cdsA 7773440 cdsA Vibrio cholerae M66-2 phosphatidate cytidylyltransferase YP_002810930.1 2348196 R 579112 CDS YP_002810931.1 227082380 7773441 complement(2349056..2349826) 1 NC_012578.1 UDP diphosphate synthase 2349826 uppS 7773441 uppS Vibrio cholerae M66-2 UDP diphosphate synthase YP_002810931.1 2349056 R 579112 CDS YP_002810932.1 227082381 7773442 complement(2349900..2350457) 1 NC_012578.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 2350457 frr 7773442 frr Vibrio cholerae M66-2 ribosome recycling factor YP_002810932.1 2349900 R 579112 CDS YP_002810933.1 227082382 7773443 complement(2350511..2351242) 1 NC_012578.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 2351242 pyrH 7773443 pyrH Vibrio cholerae M66-2 uridylate kinase YP_002810933.1 2350511 R 579112 CDS YP_002810934.1 227082383 7773444 complement(2351430..2352272) 1 NC_012578.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2352272 tsf 7773444 tsf Vibrio cholerae M66-2 elongation factor Ts YP_002810934.1 2351430 R 579112 CDS YP_002810935.1 227082384 7773445 complement(2352404..2353132) 1 NC_012578.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2353132 rpsB 7773445 rpsB Vibrio cholerae M66-2 30S ribosomal protein S2 YP_002810935.1 2352404 R 579112 CDS YP_002810936.1 227082385 7773446 2353473..2354315 1 NC_012578.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 2354315 map 7773446 map Vibrio cholerae M66-2 methionine aminopeptidase YP_002810936.1 2353473 D 579112 CDS YP_002810937.1 227082386 7773447 2354405..2357050 1 NC_012578.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 2357050 glnD 7773447 glnD Vibrio cholerae M66-2 PII uridylyl-transferase YP_002810937.1 2354405 D 579112 CDS YP_002810938.1 227082387 7773448 complement(2357125..2357223) 1 NC_012578.1 hypothetical protein 2357223 7773448 VCM66_2186 Vibrio cholerae M66-2 hypothetical protein YP_002810938.1 2357125 R 579112 CDS YP_002810939.1 227082388 7773449 2357296..2357709 1 NC_012578.1 hypothetical protein 2357709 7773449 VCM66_2187 Vibrio cholerae M66-2 hypothetical protein YP_002810939.1 2357296 D 579112 CDS YP_002810940.1 227082389 7773450 complement(2357750..2358259) 1 NC_012578.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 2358259 pgpA 7773450 pgpA Vibrio cholerae M66-2 phosphatidylglycerophosphatase A YP_002810940.1 2357750 R 579112 CDS YP_002810941.1 227082390 7773451 complement(2358256..2359260) 1 NC_012578.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 2359260 thiL 7773451 thiL Vibrio cholerae M66-2 thiamine monophosphate kinase YP_002810941.1 2358256 R 579112 CDS YP_002810942.1 227082391 7773452 complement(2359321..2359791) 1 NC_012578.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 2359791 nusB 7773452 nusB Vibrio cholerae M66-2 transcription antitermination protein NusB YP_002810942.1 2359321 R 579112 CDS YP_002810943.1 227082392 7773453 complement(2359791..2360312) 1 NC_012578.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 2360312 ribH 7773453 ribH Vibrio cholerae M66-2 6,7-dimethyl-8-ribityllumazine synthase YP_002810943.1 2359791 R 579112 CDS YP_002810944.1 227082393 7773454 complement(2360526..2361635) 1 NC_012578.1 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II 2361635 ribB/A 7773454 ribB/A Vibrio cholerae M66-2 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II YP_002810944.1 2360526 R 579112 CDS YP_002810945.1 227082394 7773455 complement(2361676..2362329) 1 NC_012578.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2362329 ribC 7773455 ribC Vibrio cholerae M66-2 riboflavin synthase subunit alpha YP_002810945.1 2361676 R 579112 CDS YP_002810946.1 227082395 7773456 complement(2362334..2363437) 1 NC_012578.1 riboflavin biosynthesis protein RibD 2363437 ribD 7773456 ribD Vibrio cholerae M66-2 riboflavin biosynthesis protein RibD YP_002810946.1 2362334 R 579112 CDS YP_002810947.1 227082396 7773457 complement(2363463..2363933) 1 NC_012578.1 transcriptional regulator NrdR 2363933 nrdR 7773457 nrdR Vibrio cholerae M66-2 transcriptional regulator NrdR YP_002810947.1 2363463 R 579112 CDS YP_002810948.1 227082397 7773458 complement(2364012..2365265) 1 NC_012578.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 2365265 proA 7773458 proA Vibrio cholerae M66-2 gamma-glutamyl phosphate reductase YP_002810948.1 2364012 R 579112 CDS YP_002810949.1 227082398 7773459 complement(2365274..2366464) 1 NC_012578.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 2366464 proB 7773459 proB Vibrio cholerae M66-2 gamma-glutamyl kinase YP_002810949.1 2365274 R 579112 CDS YP_002810950.1 227082399 7773460 complement(2366528..2366917) 1 NC_012578.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 2366917 crl 7773460 crl Vibrio cholerae M66-2 DNA-binding transcriptional regulator Crl YP_002810950.1 2366528 R 579112 CDS YP_002810951.1 227082400 7773461 complement(2367051..2368298) 1 NC_012578.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 2368298 frsA 7773461 frsA Vibrio cholerae M66-2 fermentation/respiration switch protein YP_002810951.1 2367051 R 579112 CDS YP_002810952.1 227082401 7773462 complement(2368395..2368859) 1 NC_012578.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 2368859 gpt 7773462 gpt Vibrio cholerae M66-2 xanthine-guanine phosphoribosyltransferase YP_002810952.1 2368395 R 579112 CDS YP_002810953.1 227082402 7773463 complement(2368897..2370189) 1 NC_012578.1 hypothetical protein 2370189 7773463 VCM66_2201 Vibrio cholerae M66-2 hypothetical protein YP_002810953.1 2368897 R 579112 CDS YP_002810954.1 227082403 7773464 2370936..2372540 1 NC_012578.1 aminoacyl-histidine dipeptidase 2372540 pepD 7773464 pepD Vibrio cholerae M66-2 aminoacyl-histidine dipeptidase YP_002810954.1 2370936 D 579112 CDS YP_002810955.1 227082404 7773465 2372774..2373217 1 NC_012578.1 Ribosomal protein S6 modification protein 2373217 7773465 VCM66_2203 Vibrio cholerae M66-2 Ribosomal protein S6 modification protein YP_002810955.1 2372774 D 579112 CDS YP_002810956.1 227082405 7773466 2373214..2374119 1 NC_012578.1 ribosomal protein S6 modification protein 2374119 rimK 7773466 rimK Vibrio cholerae M66-2 ribosomal protein S6 modification protein YP_002810956.1 2373214 D 579112 CDS YP_002810957.1 227082406 7773467 2374079..2375167 1 NC_012578.1 hypothetical protein 2375167 7773467 VCM66_2205 Vibrio cholerae M66-2 hypothetical protein YP_002810957.1 2374079 D 579112 CDS YP_002810958.1 227082407 7773468 complement(2375236..2376591) 1 NC_012578.1 sodium-dependent transporter 2376591 7773468 VCM66_2206 Vibrio cholerae M66-2 sodium-dependent transporter YP_002810958.1 2375236 R 579112 CDS YP_002810959.1 227082408 7773469 2376650..2376751 1 NC_012578.1 hypothetical protein 2376751 7773469 VCM66_2207 Vibrio cholerae M66-2 hypothetical protein YP_002810959.1 2376650 D 579112 CDS YP_002810960.1 227082409 7773470 complement(2376748..2378265) 1 NC_012578.1 GGDEF family protein 2378265 7773470 VCM66_2208 Vibrio cholerae M66-2 GGDEF family protein YP_002810960.1 2376748 R 579112 CDS YP_002810961.1 227082410 7773471 complement(2378329..2379099) 1 NC_012578.1 hypothetical protein 2379099 7773471 VCM66_2209 Vibrio cholerae M66-2 hypothetical protein YP_002810961.1 2378329 R 579112 CDS YP_002810962.1 227082411 7773472 complement(2379345..2380427) 1 NC_012578.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2380427 dinP 7773472 dinP Vibrio cholerae M66-2 DNA polymerase IV YP_002810962.1 2379345 R 579112 CDS YP_002810963.1 227082412 7773473 complement(2380536..2380769) 1 NC_012578.1 hypothetical protein 2380769 7773473 VCM66_2211 Vibrio cholerae M66-2 hypothetical protein YP_002810963.1 2380536 R 579112 CDS YP_002810964.1 227082413 7773474 complement(2380786..2381889) 1 NC_012578.1 thiamin biosynthesis lipoprotein ApbE 2381889 apbE 7773474 apbE Vibrio cholerae M66-2 thiamin biosynthesis lipoprotein ApbE YP_002810964.1 2380786 R 579112 CDS YP_002810965.1 227082414 7773475 complement(2381936..2383162) 1 NC_012578.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 2383162 nqrF 7773475 nqrF Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit F YP_002810965.1 2381936 R 579112 CDS YP_002810966.1 227082415 7773476 complement(2383196..2383792) 1 NC_012578.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 2383792 nqrE 7773476 nqrE Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit E YP_002810966.1 2383196 R 579112 CDS YP_002810967.1 227082416 7773477 complement(2383800..2384432) 1 NC_012578.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 2384432 nqrD 7773477 nqrD Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit D YP_002810967.1 2383800 R 579112 CDS YP_002810968.1 227082417 7773478 complement(2384432..2385205) 1 NC_012578.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 2385205 nqrC 7773478 nqrC Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit C YP_002810968.1 2384432 R 579112 CDS YP_002810969.1 227082418 7773479 complement(2385192..2386475) 1 NC_012578.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 2386475 nqrB 7773479 nqrB Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit B YP_002810969.1 2385192 R 579112 CDS YP_002810970.1 227082419 7773480 complement(2386445..2387833) 1 NC_012578.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 2387833 nqrA 7773480 nqrA Vibrio cholerae M66-2 Na(+)-translocating NADH-quinone reductase subunit A YP_002810970.1 2386445 R 579112 CDS YP_002810971.1 227082420 7773481 complement(2388270..2388590) 1 NC_012578.1 bolA protein 2388590 bolA 7773481 bolA Vibrio cholerae M66-2 bolA protein YP_002810971.1 2388270 R 579112 CDS YP_002810972.1 227082421 7773482 2388635..2389885 1 NC_012578.1 Putative ribosomal RNA small subunit methyltransferase D 2389885 7773482 VCM66_2220 Vibrio cholerae M66-2 Putative ribosomal RNA small subunit methyltransferase D YP_002810972.1 2388635 D 579112 CDS YP_002810973.1 227082422 7773483 2389882..2390502 1 NC_012578.1 putative lipoprotein 2390502 7773483 VCM66_2221 Vibrio cholerae M66-2 putative lipoprotein YP_002810973.1 2389882 D 579112 CDS YP_002810974.1 227082423 7773484 2390459..2391043 1 NC_012578.1 peptidyl-prolyl cis-trans isomerase A 2391043 ppiA 7773484 ppiA Vibrio cholerae M66-2 peptidyl-prolyl cis-trans isomerase A YP_002810974.1 2390459 D 579112 CDS YP_002810975.1 227082424 7773485 2391112..2392500 1 NC_012578.1 putative ampG protein 2392500 7773485 VCM66_2223 Vibrio cholerae M66-2 putative ampG protein YP_002810975.1 2391112 D 579112 CDS YP_002810976.1 227082425 7773486 complement(2392588..2393268) 1 NC_012578.1 putative transcriptional activator 2393268 7773486 VCM66_2224 Vibrio cholerae M66-2 putative transcriptional activator YP_002810976.1 2392588 R 579112 CDS YP_002810977.1 227082426 7773487 complement(2393265..2393849) 1 NC_012578.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 2393849 7773487 VCM66_2225 Vibrio cholerae M66-2 RNA polymerase sigma factor YP_002810977.1 2393265 R 579112 CDS YP_002810978.1 227082427 7773488 complement(2393940..2394521) 1 NC_012578.1 hypothetical protein 2394521 7773488 VCM66_2226 Vibrio cholerae M66-2 hypothetical protein YP_002810978.1 2393940 R 579112 CDS YP_002810979.1 227082428 7773489 2394590..2394700 1 NC_012578.1 hypothetical protein 2394700 7773489 VCM66_2227 Vibrio cholerae M66-2 hypothetical protein YP_002810979.1 2394590 D 579112 CDS YP_002810980.1 227082429 7773490 2394759..2395649 1 NC_012578.1 outer membrane protein OmpK 2395649 ompK 7773490 ompK Vibrio cholerae M66-2 outer membrane protein OmpK YP_002810980.1 2394759 D 579112 CDS YP_002810981.1 227082430 7773491 complement(2395646..2395738) 1 NC_012578.1 hypothetical protein 2395738 7773491 VCM66_2229 Vibrio cholerae M66-2 hypothetical protein YP_002810981.1 2395646 R 579112 CDS YP_002810982.1 227082431 7773492 2395788..2396678 1 NC_012578.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2396678 panE 7773492 panE Vibrio cholerae M66-2 2-dehydropantoate 2-reductase YP_002810982.1 2395788 D 579112 CDS YP_002810983.1 227082432 7773493 2396663..2397280 1 NC_012578.1 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein 2397280 thiJ 7773493 thiJ Vibrio cholerae M66-2 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_002810983.1 2396663 D 579112 CDS YP_002810984.1 227082433 7773494 2397264..2398478 1 NC_012578.1 class V aminotransferase 2398478 7773494 VCM66_2232 Vibrio cholerae M66-2 class V aminotransferase YP_002810984.1 2397264 D 579112 CDS YP_002810985.1 227082434 7773495 complement(2398548..2398982) 1 NC_012578.1 SufE-like protein 2398982 7773495 VCM66_2233 Vibrio cholerae M66-2 SufE-like protein YP_002810985.1 2398548 R 579112 CDS YP_002810986.1 227082435 7773496 complement(2398987..2399808) 1 NC_012578.1 HesA/MoeB/ThiF family protein 2399808 7773496 VCM66_2234 Vibrio cholerae M66-2 HesA/MoeB/ThiF family protein YP_002810986.1 2398987 R 579112 CDS YP_002810987.1 227082436 7773497 complement(2399900..2401006) 1 NC_012578.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 2401006 mltA 7773497 mltA Vibrio cholerae M66-2 murein transglycosylase A YP_002810987.1 2399900 R 579112 CDS YP_002810988.1 227082437 7773498 2400970..2401080 1 NC_012578.1 hypothetical protein 2401080 7773498 VCM66_2236 Vibrio cholerae M66-2 hypothetical protein YP_002810988.1 2400970 D 579112 CDS YP_002810989.1 227082438 7773499 complement(2401077..2401481) 1 NC_012578.1 hypothetical protein 2401481 7773499 VCM66_2237 Vibrio cholerae M66-2 hypothetical protein YP_002810989.1 2401077 R 579112 CDS YP_002810990.1 227082439 7773500 complement(2401530..2401625) 1 NC_012578.1 hypothetical protein 2401625 7773500 VCM66_2238 Vibrio cholerae M66-2 hypothetical protein YP_002810990.1 2401530 R 579112 CDS YP_002810991.1 227082440 7773501 2401717..2403087 1 NC_012578.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2403087 argA 7773501 argA Vibrio cholerae M66-2 N-acetylglutamate synthase YP_002810991.1 2401717 D 579112 CDS YP_002810992.1 227082441 7773502 complement(2403061..2403225) 1 NC_012578.1 hypothetical protein 2403225 7773502 VCM66_2240 Vibrio cholerae M66-2 hypothetical protein YP_002810992.1 2403061 R 579112 CDS YP_002810993.1 227082442 7773503 2403314..2403499 1 NC_012578.1 hypothetical protein 2403499 7773503 VCM66_2241 Vibrio cholerae M66-2 hypothetical protein YP_002810993.1 2403314 D 579112 CDS YP_002810994.1 227082443 7773504 complement(2403529..2405649) 1 NC_012578.1 exodeoxyribonuclease V, 67 kDa subunit 2405649 recD 7773504 recD Vibrio cholerae M66-2 exodeoxyribonuclease V, 67 kDa subunit YP_002810994.1 2403529 R 579112 CDS YP_002810995.1 227082444 7773505 complement(2405646..2409272) 1 NC_012578.1 exodeoxyribonuclease V, 135 kDa subunit 2409272 recB 7773505 recB Vibrio cholerae M66-2 exodeoxyribonuclease V, 135 kDa subunit YP_002810995.1 2405646 R 579112 CDS YP_002810996.1 227082445 7773506 complement(2409429..2409530) 1 NC_012578.1 hypothetical protein 2409530 7773506 VCM66_2244 Vibrio cholerae M66-2 hypothetical protein YP_002810996.1 2409429 R 579112 CDS YP_002810997.1 227082446 7773507 complement(2409537..2412983) 1 NC_012578.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 2412983 recC 7773507 recC Vibrio cholerae M66-2 exonuclease V subunit gamma YP_002810997.1 2409537 R 579112 CDS YP_002810998.1 227082447 7773508 complement(2413222..2414190) 1 NC_012578.1 hypothetical protein 2414190 7773508 VCM66_2246 Vibrio cholerae M66-2 hypothetical protein YP_002810998.1 2413222 R 579112 CDS YP_002810999.1 227082448 7773509 2414301..2415215 1 NC_012578.1 LysR family transcriptional regulator 2415215 7773509 VCM66_2247 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002810999.1 2414301 D 579112 CDS YP_002811000.1 227082449 7773510 2415170..2415280 1 NC_012578.1 hypothetical protein 2415280 7773510 VCM66_2248 Vibrio cholerae M66-2 hypothetical protein YP_002811000.1 2415170 D 579112 CDS YP_002811001.1 227082450 7773511 2415331..2415639 1 NC_012578.1 hypothetical protein 2415639 7773511 VCM66_2249 Vibrio cholerae M66-2 hypothetical protein YP_002811001.1 2415331 D 579112 CDS YP_002811002.1 227082451 7773512 complement(2415640..2415738) 1 NC_012578.1 hypothetical protein 2415738 7773512 VCM66_2250 Vibrio cholerae M66-2 hypothetical protein YP_002811002.1 2415640 R 579112 CDS YP_002811003.1 227082452 7773513 2415933..2416064 1 NC_012578.1 hypothetical protein 2416064 7773513 VCM66_2251 Vibrio cholerae M66-2 hypothetical protein YP_002811003.1 2415933 D 579112 CDS YP_002811004.1 227082453 7773514 2416046..2417077 1 NC_012578.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 2417077 dapD 7773514 dapD Vibrio cholerae M66-2 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_002811004.1 2416046 D 579112 CDS YP_002811005.1 227082454 7773515 complement(2417159..2418403) 1 NC_012578.1 hypothetical protein 2418403 7773515 VCM66_2253 Vibrio cholerae M66-2 hypothetical protein YP_002811005.1 2417159 R 579112 CDS YP_002811006.1 227082455 7773516 complement(2418366..2418473) 1 NC_012578.1 hypothetical protein 2418473 7773516 VCM66_2254 Vibrio cholerae M66-2 hypothetical protein YP_002811006.1 2418366 R 579112 CDS YP_002811007.1 227082456 7773517 complement(2418506..2419597) 1 NC_012578.1 GNAT family acetyltransferase 2419597 7773517 VCM66_2255 Vibrio cholerae M66-2 GNAT family acetyltransferase YP_002811007.1 2418506 R 579112 CDS YP_002811008.1 227082457 7773518 2419802..2421253 1 NC_012578.1 ribosomal protein S6 modification protein-like protein 2421253 7773518 VCM66_2256 Vibrio cholerae M66-2 ribosomal protein S6 modification protein-like protein YP_002811008.1 2419802 D 579112 CDS YP_002811009.1 227082458 7773519 2421443..2422426 1 NC_012578.1 Zinc transport protein zntB 2422426 7773519 VCM66_2257 Vibrio cholerae M66-2 Zinc transport protein zntB YP_002811009.1 2421443 D 579112 CDS YP_002811010.1 227082459 7773520 2422410..2422997 1 NC_012578.1 hypothetical protein 2422997 7773520 VCM66_2258 Vibrio cholerae M66-2 hypothetical protein YP_002811010.1 2422410 D 579112 CDS YP_002811011.1 227082460 7773521 complement(2422994..2423338) 1 NC_012578.1 hypothetical protein 2423338 7773521 VCM66_2259 Vibrio cholerae M66-2 hypothetical protein YP_002811011.1 2422994 R 579112 CDS YP_002811012.1 227082461 7773522 2423497..2424504 1 NC_012578.1 LacI family transcriptional regulator 2424504 7773522 VCM66_2260 Vibrio cholerae M66-2 LacI family transcriptional regulator YP_002811012.1 2423497 D 579112 CDS YP_002811013.1 227082462 7773523 complement(2424516..2427650) 1 NC_012578.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 2427650 lacZ 7773523 lacZ Vibrio cholerae M66-2 beta-D-galactosidase YP_002811013.1 2424516 R 579112 CDS YP_002811014.1 227082463 7773524 2427973..2429115 1 NC_012578.1 chromate resistance protein-like protein 2429115 7773524 VCM66_2262 Vibrio cholerae M66-2 chromate resistance protein-like protein YP_002811014.1 2427973 D 579112 CDS YP_002811015.1 227082464 7773525 2429251..2430405 1 NC_012578.1 rpfG-type response regulator 2430405 7773525 VCM66_2263 Vibrio cholerae M66-2 rpfG-type response regulator YP_002811015.1 2429251 D 579112 CDS YP_002811016.1 227082465 7773526 2430605..2432296 1 NC_012578.1 putative long-chain-fatty-acid--CoA ligase 2432296 7773526 VCM66_2264 Vibrio cholerae M66-2 putative long-chain-fatty-acid--CoA ligase YP_002811016.1 2430605 D 579112 CDS YP_002811017.1 227082466 7773527 complement(2432410..2434497) 1 NC_012578.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2434497 fusA-2 7773527 fusA-2 Vibrio cholerae M66-2 elongation factor G YP_002811017.1 2432410 R 579112 CDS YP_002811018.1 227082467 7773528 complement(2434768..2436147) 1 NC_012578.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 2436147 radA 7773528 radA Vibrio cholerae M66-2 DNA repair protein RadA YP_002811018.1 2434768 R 579112 CDS YP_002811019.1 227082468 7773529 2436275..2438614 1 NC_012578.1 hypothetical protein 2438614 7773529 VCM66_2267 Vibrio cholerae M66-2 hypothetical protein YP_002811019.1 2436275 D 579112 CDS YP_002811020.1 227082469 7773530 complement(2438819..2439805) 1 NC_012578.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 2439805 serB 7773530 serB Vibrio cholerae M66-2 phosphoserine phosphatase YP_002811020.1 2438819 R 579112 CDS YP_002811021.1 227082470 7773531 2439902..2440525 1 NC_012578.1 putative smp protein 2440525 7773531 VCM66_2269 Vibrio cholerae M66-2 putative smp protein YP_002811021.1 2439902 D 579112 CDS YP_002811022.1 227082471 7773532 complement(2440607..2441332) 1 NC_012578.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 2441332 deoD 7773532 deoD Vibrio cholerae M66-2 purine nucleoside phosphorylase YP_002811022.1 2440607 R 579112 CDS YP_002811023.1 227082472 7773533 complement(2441415..2442635) 1 NC_012578.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 2442635 deoB 7773533 deoB Vibrio cholerae M66-2 phosphopentomutase YP_002811023.1 2441415 R 579112 CDS YP_002811024.1 227082473 7773534 complement(2442653..2444080) 1 NC_012578.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 2444080 deoA 7773534 deoA Vibrio cholerae M66-2 thymidine phosphorylase YP_002811024.1 2442653 R 579112 CDS YP_002811025.1 227082474 7773535 complement(2444087..2444866) 1 NC_012578.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 2444866 deoC 7773535 deoC Vibrio cholerae M66-2 deoxyribose-phosphate aldolase YP_002811025.1 2444087 R 579112 CDS YP_002811026.1 227082475 7773536 2444968..2445156 1 NC_012578.1 hypothetical protein 2445156 7773536 VCM66_2274 Vibrio cholerae M66-2 hypothetical protein YP_002811026.1 2444968 D 579112 CDS YP_002811027.1 227082476 7773537 complement(2445468..2446724) 1 NC_012578.1 NupC family protein 2446724 7773537 VCM66_2275 Vibrio cholerae M66-2 NupC family protein YP_002811027.1 2445468 R 579112 CDS YP_002811028.1 227082477 7773538 complement(2446911..2447762) 1 NC_012578.1 Putative deoxyribonuclease yjjV 2447762 7773538 VCM66_2276 Vibrio cholerae M66-2 Putative deoxyribonuclease yjjV YP_002811028.1 2446911 R 579112 CDS YP_002811029.1 227082478 7773539 complement(2447707..2447850) 1 NC_012578.1 hypothetical protein 2447850 7773539 VCM66_2277 Vibrio cholerae M66-2 hypothetical protein YP_002811029.1 2447707 R 579112 CDS YP_002811030.1 227082479 7773540 complement(2447877..2448650) 1 NC_012578.1 hypothetical protein 2448650 7773540 VCM66_2278 Vibrio cholerae M66-2 hypothetical protein YP_002811030.1 2447877 R 579112 CDS YP_002811031.1 227082480 7773541 complement(2448814..2450244) 1 NC_012578.1 sodium/alanine symporter 2450244 7773541 VCM66_2279 Vibrio cholerae M66-2 sodium/alanine symporter YP_002811031.1 2448814 R 579112 CDS YP_002811032.1 227082481 7773542 2450883..2451116 1 NC_012578.1 hypothetical protein 2451116 7773542 VCM66_2280 Vibrio cholerae M66-2 hypothetical protein YP_002811032.1 2450883 D 579112 CDS YP_002811033.1 227082482 7773543 complement(2451260..2451901) 1 NC_012578.1 hypothetical protein 2451901 7773543 VCM66_2281 Vibrio cholerae M66-2 hypothetical protein YP_002811033.1 2451260 R 579112 CDS YP_002811034.1 227082483 7773544 complement(2451901..2452581) 1 NC_012578.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2452581 ung 7773544 ung Vibrio cholerae M66-2 uracil-DNA glycosylase YP_002811034.1 2451901 R 579112 CDS YP_002811035.1 227082484 7773545 complement(2452950..2453810) 1 NC_012578.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2453810 nfo 7773545 nfo Vibrio cholerae M66-2 endonuclease IV YP_002811035.1 2452950 R 579112 CDS YP_002811036.1 227082485 7773546 2454156..2454533 1 NC_012578.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2454533 7773546 VCM66_2284 Vibrio cholerae M66-2 autonomous glycyl radical cofactor GrcA YP_002811036.1 2454156 D 579112 CDS YP_002811037.1 227082486 7773547 complement(2454613..2455893) 1 NC_012578.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2455893 thrC 7773547 thrC Vibrio cholerae M66-2 threonine synthase YP_002811037.1 2454613 R 579112 CDS YP_002811038.1 227082487 7773548 complement(2455890..2456846) 1 NC_012578.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2456846 thrB 7773548 thrB Vibrio cholerae M66-2 homoserine kinase YP_002811038.1 2455890 R 579112 CDS YP_002811039.1 227082488 7773549 complement(2456867..2459344) 1 NC_012578.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2459344 thrA 7773549 thrA Vibrio cholerae M66-2 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002811039.1 2456867 R 579112 CDS YP_002811040.1 227082489 7773550 2459874..2460356 1 NC_012578.1 hypothetical protein 2460356 7773550 VCM66_2288 Vibrio cholerae M66-2 hypothetical protein YP_002811040.1 2459874 D 579112 CDS YP_002811041.1 227082490 7773551 complement(2460353..2460841) 1 NC_012578.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 2460841 menG-1 7773551 menG-1 Vibrio cholerae M66-2 ribonuclease activity regulator protein RraA YP_002811041.1 2460353 R 579112 CDS YP_002811042.1 227082491 7773552 complement(2460868..2461251) 1 NC_012578.1 hypothetical protein 2461251 7773552 VCM66_2290 Vibrio cholerae M66-2 hypothetical protein YP_002811042.1 2460868 R 579112 CDS YP_002811043.1 227082492 7773553 2461566..2462282 1 NC_012578.1 two-component response regulator 2462282 fexA 7773553 fexA Vibrio cholerae M66-2 two-component response regulator YP_002811043.1 2461566 D 579112 CDS YP_002811044.1 227082493 7773554 complement(2462341..2464698) 1 NC_012578.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 2464698 fexB 7773554 fexB Vibrio cholerae M66-2 aerobic respiration control sensor protein ArcB YP_002811044.1 2462341 R 579112 CDS YP_002811045.1 227082494 7773555 complement(2464805..2466544) 1 NC_012578.1 PAS/GGDEF family protein 2466544 7773555 VCM66_2293 Vibrio cholerae M66-2 PAS/GGDEF family protein YP_002811045.1 2464805 R 579112 CDS YP_002811046.1 227082495 7773556 complement(2466612..2467562) 1 NC_012578.1 hypothetical protein 2467562 7773556 VCM66_2294 Vibrio cholerae M66-2 hypothetical protein YP_002811046.1 2466612 R 579112 CDS YP_002811047.1 227082496 7773557 complement(2467584..2467703) 1 NC_012578.1 hypothetical protein 2467703 7773557 VCM66_2295 Vibrio cholerae M66-2 hypothetical protein YP_002811047.1 2467584 R 579112 CDS YP_002811048.1 227082497 7773558 2468081..2472673 1 NC_012578.1 glutamate synthase, large subunit 2472673 gltB-1 7773558 gltB-1 Vibrio cholerae M66-2 glutamate synthase, large subunit YP_002811048.1 2468081 D 579112 CDS YP_002811049.1 227082498 7773559 2472674..2474143 1 NC_012578.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 2474143 gltD 7773559 gltD Vibrio cholerae M66-2 glutamate synthase subunit beta YP_002811049.1 2472674 D 579112 CDS YP_002811050.1 227082499 7773560 2474177..2474287 1 NC_012578.1 hypothetical protein 2474287 7773560 VCM66_2298 Vibrio cholerae M66-2 hypothetical protein YP_002811050.1 2474177 D 579112 CDS YP_002811051.1 227082500 7773561 2474671..2479134 1 NC_012578.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 2479134 gltB 7773561 gltB Vibrio cholerae M66-2 glutamate synthase subunit alpha YP_002811051.1 2474671 D 579112 CDS YP_002811052.1 227082501 7773562 2479150..2480565 1 NC_012578.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 2480565 gltD 7773562 gltD Vibrio cholerae M66-2 glutamate synthase subunit beta YP_002811052.1 2479150 D 579112 CDS YP_002811053.1 227082502 7773563 2480752..2481186 1 NC_012578.1 hypothetical protein 2481186 7773563 VCM66_2301 Vibrio cholerae M66-2 hypothetical protein YP_002811053.1 2480752 D 579112 CDS YP_002811054.1 227082503 7773564 2481274..2481969 1 NC_012578.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2481969 pfs 7773564 pfs Vibrio cholerae M66-2 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002811054.1 2481274 D 579112 CDS YP_002811055.1 227082504 7773565 2481982..2482935 1 NC_012578.1 catalyzes the formation of adenosylcobinamide-phosphate from adenosylcobyric acid; adenosylcobinamide-phosphate synthase 2482935 7773565 VCM66_2303 Vibrio cholerae M66-2 adenosylcobinamide-phosphate synthase YP_002811055.1 2481982 D 579112 CDS YP_002811056.1 227082505 7773566 2482936..2483766 1 NC_012578.1 Vitamin B12-binding protein 2483766 7773566 VCM66_2304 Vibrio cholerae M66-2 Vitamin B12-binding protein YP_002811056.1 2482936 D 579112 CDS YP_002811057.1 227082506 7773567 2483750..2484469 1 NC_012578.1 hypothetical protein 2484469 7773567 VCM66_2305 Vibrio cholerae M66-2 hypothetical protein YP_002811057.1 2483750 D 579112 CDS YP_002811058.1 227082507 7773568 2484621..2485481 1 NC_012578.1 LysR family transcriptional regulator 2485481 7773568 VCM66_2306 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002811058.1 2484621 D 579112 CDS YP_002811059.1 227082508 7773569 complement(2485411..2486196) 1 NC_012578.1 putative Inner membrane protein 2486196 7773569 VCM66_2307 Vibrio cholerae M66-2 putative Inner membrane protein YP_002811059.1 2485411 R 579112 CDS YP_002811060.1 227082509 7773570 2486658..2487629 1 NC_012578.1 RNA-directed DNA polymerase 2487629 7773570 VCM66_2308 Vibrio cholerae M66-2 RNA-directed DNA polymerase YP_002811060.1 2486658 D 579112 CDS YP_002811061.1 227082510 7773966 2489264..2489881 1 NC_012578.1 hypothetical protein 2489881 7773966 VCM66_2310 Vibrio cholerae M66-2 hypothetical protein YP_002811061.1 2489264 D 579112 CDS YP_002811062.1 227082511 7773572 2490492..2490974 1 NC_012578.1 hypothetical protein 2490974 7773572 VCM66_2311 Vibrio cholerae M66-2 hypothetical protein YP_002811062.1 2490492 D 579112 CDS YP_002811063.1 227082512 7773573 complement(2491064..2494294) 1 NC_012578.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 2494294 carB 7773573 carB Vibrio cholerae M66-2 carbamoyl phosphate synthase large subunit YP_002811063.1 2491064 R 579112 CDS YP_002811064.1 227082513 7773574 complement(2494311..2495450) 1 NC_012578.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2495450 carA 7773574 carA Vibrio cholerae M66-2 carbamoyl phosphate synthase small subunit YP_002811064.1 2494311 R 579112 CDS YP_002811065.1 227082514 7773575 complement(2495933..2496742) 1 NC_012578.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 2496742 dapB 7773575 dapB Vibrio cholerae M66-2 dihydrodipicolinate reductase YP_002811065.1 2495933 R 579112 CDS YP_002811066.1 227082515 7773576 complement(2496857..2497255) 1 NC_012578.1 mutator MutT protein 2497255 mutT 7773576 mutT Vibrio cholerae M66-2 mutator MutT protein YP_002811066.1 2496857 R 579112 CDS YP_002811067.1 227082516 7773577 2497241..2497408 1 NC_012578.1 hypothetical protein 2497408 7773577 VCM66_2316 Vibrio cholerae M66-2 hypothetical protein YP_002811067.1 2497241 D 579112 CDS YP_002811068.1 227082517 7773578 complement(2497405..2500116) 1 NC_012578.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 2500116 secA 7773578 secA Vibrio cholerae M66-2 preprotein translocase subunit SecA YP_002811068.1 2497405 R 579112 CDS YP_002811069.1 227082518 7773579 2500470..2500943 1 NC_012578.1 hypothetical protein 2500943 7773579 VCM66_2318 Vibrio cholerae M66-2 hypothetical protein YP_002811069.1 2500470 D 579112 CDS YP_002811070.1 227082519 7773580 complement(2501048..2501965) 1 NC_012578.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2501965 lpxC 7773580 lpxC Vibrio cholerae M66-2 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002811070.1 2501048 R 579112 CDS YP_002811071.1 227082520 7773581 complement(2502063..2503259) 1 NC_012578.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2503259 ftsz 7773581 ftsz Vibrio cholerae M66-2 cell division protein FtsZ YP_002811071.1 2502063 R 579112 CDS YP_002811072.1 227082521 7773582 complement(2503290..2504552) 1 NC_012578.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 2504552 ftsA 7773582 ftsA Vibrio cholerae M66-2 cell division protein FtsA YP_002811072.1 2503290 R 579112 CDS YP_002811073.1 227082522 7773583 complement(2504545..2505327) 1 NC_012578.1 cell division protein FtsQ 2505327 ftsQ 7773583 ftsQ Vibrio cholerae M66-2 cell division protein FtsQ YP_002811073.1 2504545 R 579112 CDS YP_002811074.1 227082523 7773584 complement(2505509..2507029) 1 NC_012578.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 2507029 murC 7773584 murC Vibrio cholerae M66-2 UDP-N-acetylmuramate--L-alanine ligase YP_002811074.1 2505509 R 579112 CDS YP_002811075.1 227082524 7773585 complement(2506983..2508047) 1 NC_012578.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 2508047 murG 7773585 murG Vibrio cholerae M66-2 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002811075.1 2506983 R 579112 CDS YP_002811076.1 227082525 7773586 complement(2508031..2509227) 1 NC_012578.1 cell division protein FtsW 2509227 ftsW 7773586 ftsW Vibrio cholerae M66-2 cell division protein FtsW YP_002811076.1 2508031 R 579112 CDS YP_002811077.1 227082526 7773587 complement(2509244..2510647) 1 NC_012578.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2510647 murD 7773587 murD Vibrio cholerae M66-2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002811077.1 2509244 R 579112 CDS YP_002811078.1 227082527 7773588 complement(2510590..2511672) 1 NC_012578.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2511672 mraY 7773588 mraY Vibrio cholerae M66-2 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002811078.1 2510590 R 579112 CDS YP_002811079.1 227082528 7773589 complement(2511669..2513030) 1 NC_012578.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 2513030 murF 7773589 murF Vibrio cholerae M66-2 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase YP_002811079.1 2511669 R 579112 CDS YP_002811080.1 227082529 7773590 complement(2513027..2514565) 1 NC_012578.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2514565 murE 7773590 murE Vibrio cholerae M66-2 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002811080.1 2513027 R 579112 CDS YP_002811081.1 227082530 7773591 complement(2514531..2516273) 1 NC_012578.1 penicillin-binding protein 3 2516273 ftsI 7773591 ftsI Vibrio cholerae M66-2 penicillin-binding protein 3 YP_002811081.1 2514531 R 579112 CDS YP_002811082.1 227082531 7773592 complement(2516270..2516590) 1 NC_012578.1 cell division protein FtsL 2516590 ftsL 7773592 ftsL Vibrio cholerae M66-2 cell division protein FtsL YP_002811082.1 2516270 R 579112 CDS YP_002811083.1 227082532 7773593 complement(2516600..2517550) 1 NC_012578.1 S-adenosyl-methyltransferase MraW 2517550 mraW 7773593 mraW Vibrio cholerae M66-2 S-adenosyl-methyltransferase MraW YP_002811083.1 2516600 R 579112 CDS YP_002811084.1 227082533 7773594 complement(2518322..2519749) 1 NC_012578.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2519749 lpdA 7773594 lpdA Vibrio cholerae M66-2 dihydrolipoamide dehydrogenase YP_002811084.1 2518322 R 579112 CDS YP_002811085.1 227082534 7773595 complement(2520017..2521930) 1 NC_012578.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 2521930 aceF 7773595 aceF Vibrio cholerae M66-2 dihydrolipoamide acetyltransferase YP_002811085.1 2520017 R 579112 CDS YP_002811086.1 227082535 7773596 complement(2521931..2524591) 1 NC_012578.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 2524591 aceE 7773596 aceE Vibrio cholerae M66-2 pyruvate dehydrogenase subunit E1 YP_002811086.1 2521931 R 579112 CDS YP_002811087.1 227082536 7773597 complement(2524641..2525411) 1 NC_012578.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 2525411 pdhR 7773597 pdhR Vibrio cholerae M66-2 transcriptional regulator PdhR YP_002811087.1 2524641 R 579112 CDS YP_002811088.1 227082537 7773598 2525895..2527799 1 NC_012578.1 putative 2,3-cyclic-nucleotide 2-phosphodiesterase 2527799 7773598 VCM66_2339 Vibrio cholerae M66-2 putative 2,3-cyclic-nucleotide 2-phosphodiesterase YP_002811088.1 2525895 D 579112 CDS YP_002811089.1 227082538 7773599 complement(2527844..2529598) 1 NC_012578.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 2529598 recJ 7773599 recJ Vibrio cholerae M66-2 ssDNA exonuclease RecJ YP_002811089.1 2527844 R 579112 CDS YP_002811090.1 227082539 7773600 complement(2529642..2530394) 1 NC_012578.1 thiol:disulfide interchange protein DsbC 2530394 dsbC 7773600 dsbC Vibrio cholerae M66-2 thiol:disulfide interchange protein DsbC YP_002811090.1 2529642 R 579112 CDS YP_002811091.1 227082540 7773601 complement(2530411..2531319) 1 NC_012578.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 2531319 xerD 7773601 xerD Vibrio cholerae M66-2 site-specific tyrosine recombinase XerD YP_002811091.1 2530411 R 579112 CDS YP_002811092.1 227082541 7773602 2531379..2531975 1 NC_012578.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2531975 fldB 7773602 fldB Vibrio cholerae M66-2 flavodoxin FldB YP_002811092.1 2531379 D 579112 CDS YP_002811093.1 227082542 7773603 complement(2532253..2532798) 1 NC_012578.1 N-acetyl-anhydromuranmyl-L-alanine amidase 2532798 ampD 7773603 ampD Vibrio cholerae M66-2 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002811093.1 2532253 R 579112 CDS YP_002811094.1 227082543 7773604 2533094..2533984 1 NC_012578.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 2533984 nadC 7773604 nadC Vibrio cholerae M66-2 quinolinate phosphoribosyltransferase YP_002811094.1 2533094 D 579112 CDS YP_002811095.1 227082544 7773605 2534187..2534690 1 NC_012578.1 fimbrial protein 2534690 pilA 7773605 pilA Vibrio cholerae M66-2 fimbrial protein YP_002811095.1 2534187 D 579112 CDS YP_002811096.1 227082545 7773606 2534690..2536378 1 NC_012578.1 type IV pilus assembly protein PilB 2536378 pilB 7773606 pilB Vibrio cholerae M66-2 type IV pilus assembly protein PilB YP_002811096.1 2534690 D 579112 CDS YP_002811097.1 227082546 7773607 2536421..2537647 1 NC_012578.1 type IV pilin biogenesis protein PilC 2537647 pilC 7773607 pilC Vibrio cholerae M66-2 type IV pilin biogenesis protein PilC YP_002811097.1 2536421 D 579112 CDS YP_002811098.1 227082547 7773608 2537705..2538580 1 NC_012578.1 leader peptidase PilD 2538580 pilD 7773608 pilD Vibrio cholerae M66-2 leader peptidase PilD YP_002811098.1 2537705 D 579112 CDS YP_002811099.1 227082548 7773609 2538544..2539185 1 NC_012578.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2539185 coaE 7773609 coaE Vibrio cholerae M66-2 dephospho-CoA kinase YP_002811099.1 2538544 D 579112 CDS YP_002811100.1 227082549 7773610 2539217..2539957 1 NC_012578.1 hypothetical protein 2539957 7773610 VCM66_2351 Vibrio cholerae M66-2 hypothetical protein YP_002811100.1 2539217 D 579112 CDS YP_002811101.1 227082550 7773611 2540099..2540296 1 NC_012578.1 zinc-binding protein 2540296 7773611 VCM66_2352 Vibrio cholerae M66-2 zinc-binding protein YP_002811101.1 2540099 D 579112 CDS YP_002811102.1 227082551 7773612 complement(2540345..2542630) 1 NC_012578.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 2542630 parC 7773612 parC Vibrio cholerae M66-2 DNA topoisomerase IV subunit A YP_002811102.1 2540345 R 579112 CDS YP_002811103.1 227082552 7773613 complement(2542634..2544514) 1 NC_012578.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 2544514 parE 7773613 parE Vibrio cholerae M66-2 DNA topoisomerase IV subunit B YP_002811103.1 2542634 R 579112 CDS YP_002811104.1 227082553 7773614 complement(2544843..2545430) 1 NC_012578.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 2545430 7773614 VCM66_2355 Vibrio cholerae M66-2 esterase YqiA YP_002811104.1 2544843 R 579112 CDS YP_002811105.1 227082554 7773615 complement(2545432..2546250) 1 NC_012578.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 2546250 cpdA 7773615 cpdA Vibrio cholerae M66-2 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002811105.1 2545432 R 579112 CDS YP_002811106.1 227082555 7773616 complement(2546275..2546721) 1 NC_012578.1 hypothetical protein 2546721 7773616 VCM66_2357 Vibrio cholerae M66-2 hypothetical protein YP_002811106.1 2546275 R 579112 CDS YP_002811107.1 227082556 7773617 complement(2546728..2547354) 1 NC_012578.1 MutT/nudix family protein 2547354 7773617 VCM66_2358 Vibrio cholerae M66-2 MutT/nudix family protein YP_002811107.1 2546728 R 579112 CDS YP_002811108.1 227082557 7773618 2547586..2548902 1 NC_012578.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 2548902 tolC 7773618 tolC Vibrio cholerae M66-2 outer membrane channel protein YP_002811108.1 2547586 D 579112 CDS YP_002811109.1 227082558 7773619 complement(2549008..2550438) 1 NC_012578.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 2550438 7773619 VCM66_2360 Vibrio cholerae M66-2 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002811109.1 2549008 R 579112 CDS YP_002811110.1 227082559 7773620 complement(2550502..2553348) 1 NC_012578.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 2553348 glnE 7773620 glnE Vibrio cholerae M66-2 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002811110.1 2550502 R 579112 CDS YP_002811111.1 227082560 7773621 complement(2553472..2554773) 1 NC_012578.1 methyl-accepting chemotaxis protein 2554773 7773621 VCM66_2362 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811111.1 2553472 R 579112 CDS YP_002811112.1 227082561 7773622 complement(2555213..2556730) 1 NC_012578.1 hypothetical protein 2556730 7773622 VCM66_2363 Vibrio cholerae M66-2 hypothetical protein YP_002811112.1 2555213 R 579112 CDS YP_002811113.1 227082562 7773623 2556930..2557616 1 NC_012578.1 hypothetical protein 2557616 7773623 VCM66_2364 Vibrio cholerae M66-2 hypothetical protein YP_002811113.1 2556930 D 579112 CDS YP_002811114.1 227082563 7773624 2557720..2559021 1 NC_012578.1 pho4 family protein 2559021 7773624 VCM66_2365 Vibrio cholerae M66-2 pho4 family protein YP_002811114.1 2557720 D 579112 CDS YP_002811115.1 227082564 7773625 2559188..2559796 1 NC_012578.1 hypothetical protein 2559796 7773625 VCM66_2366 Vibrio cholerae M66-2 hypothetical protein YP_002811115.1 2559188 D 579112 CDS YP_002811116.1 227082565 7773626 complement(2559888..2560658) 1 NC_012578.1 putative general secretion pathway protein B 2560658 7773626 VCM66_2367 Vibrio cholerae M66-2 putative general secretion pathway protein B YP_002811116.1 2559888 R 579112 CDS YP_002811117.1 227082566 7773627 complement(2560658..2562247) 1 NC_012578.1 general secretion pathway protein A 2562247 exeA 7773627 exeA Vibrio cholerae M66-2 general secretion pathway protein A YP_002811117.1 2560658 R 579112 CDS YP_002811118.1 227082567 7773628 2562340..2563551 1 NC_012578.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 2563551 cca 7773628 cca Vibrio cholerae M66-2 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002811118.1 2562340 D 579112 CDS YP_002811119.1 227082568 7773629 complement(2563653..2564954) 1 NC_012578.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2564954 eno 7773629 eno Vibrio cholerae M66-2 phosphopyruvate hydratase YP_002811119.1 2563653 R 579112 CDS YP_002811120.1 227082569 7773630 complement(2565033..2566670) 1 NC_012578.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2566670 pyrG 7773630 pyrG Vibrio cholerae M66-2 CTP synthetase YP_002811120.1 2565033 R 579112 CDS YP_002811121.1 227082570 7773631 2566756..2566896 1 NC_012578.1 hypothetical protein 2566896 7773631 VCM66_2372 Vibrio cholerae M66-2 hypothetical protein YP_002811121.1 2566756 D 579112 CDS YP_002811122.1 227082571 7773632 complement(2566945..2567781) 1 NC_012578.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 2567781 mazG 7773632 mazG Vibrio cholerae M66-2 nucleoside triphosphate pyrophosphohydrolase YP_002811122.1 2566945 R 579112 CDS YP_002811123.1 227082572 7773633 complement(2567860..2570076) 1 NC_012578.1 GTP pyrophosphokinase 2570076 relA 7773633 relA Vibrio cholerae M66-2 GTP pyrophosphokinase YP_002811123.1 2567860 R 579112 CDS YP_002811124.1 227082573 7773634 complement(2570140..2571462) 1 NC_012578.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 2571462 rumA 7773634 rumA Vibrio cholerae M66-2 23S rRNA 5-methyluridine methyltransferase YP_002811124.1 2570140 R 579112 CDS YP_002811125.1 227082574 7773635 2571634..2574417 1 NC_012578.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2574417 7773635 VCM66_2376 Vibrio cholerae M66-2 hybrid sensory histidine kinase BarA YP_002811125.1 2571634 D 579112 CDS YP_002811126.1 227082575 7773636 complement(2574405..2575697) 1 NC_012578.1 GGDEF family protein 2575697 vpvC 7773636 vpvC Vibrio cholerae M66-2 GGDEF family protein YP_002811126.1 2574405 R 579112 CDS YP_002811127.1 227082576 7773637 complement(2575690..2576100) 1 NC_012578.1 hypothetical protein 2576100 7773637 VCM66_2378 Vibrio cholerae M66-2 hypothetical protein YP_002811127.1 2575690 R 579112 CDS YP_002811128.1 227082577 7773638 complement(2576110..2577447) 1 NC_012578.1 hypothetical protein 2577447 7773638 VCM66_2379 Vibrio cholerae M66-2 hypothetical protein YP_002811128.1 2576110 R 579112 CDS YP_002811129.1 227082578 7773639 complement(2577650..2578030) 1 NC_012578.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2578030 acpS 7773639 acpS Vibrio cholerae M66-2 4'-phosphopantetheinyl transferase YP_002811129.1 2577650 R 579112 CDS YP_002811130.1 227082579 7773640 complement(2578034..2578765) 1 NC_012578.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2578765 pdxJ 7773640 pdxJ Vibrio cholerae M66-2 pyridoxine 5'-phosphate synthase YP_002811130.1 2578034 R 579112 CDS YP_002811131.1 227082580 7773641 complement(2578762..2579487) 1 NC_012578.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2579487 recO 7773641 recO Vibrio cholerae M66-2 DNA repair protein RecO YP_002811131.1 2578762 R 579112 CDS YP_002811132.1 227082581 7773642 complement(2579557..2580534) 1 NC_012578.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2580534 era 7773642 era Vibrio cholerae M66-2 GTP-binding protein Era YP_002811132.1 2579557 R 579112 CDS YP_002811133.1 227082582 7773643 complement(2580527..2581204) 1 NC_012578.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2581204 rnc 7773643 rnc Vibrio cholerae M66-2 ribonuclease III YP_002811133.1 2580527 R 579112 CDS YP_002811134.1 227082583 7773644 complement(2581236..2582132) 1 NC_012578.1 signal peptidase I 2582132 lepB 7773644 lepB Vibrio cholerae M66-2 signal peptidase I YP_002811134.1 2581236 R 579112 CDS YP_002811135.1 227082584 7773645 complement(2582224..2584017) 1 NC_012578.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2584017 lepA 7773645 lepA Vibrio cholerae M66-2 GTP-binding protein LepA YP_002811135.1 2582224 R 579112 CDS YP_002811136.1 227082585 7773646 complement(2584130..2584600) 1 NC_012578.1 sigma-E factor regulatory protein RseC 2584600 rseC 7773646 rseC Vibrio cholerae M66-2 sigma-E factor regulatory protein RseC YP_002811136.1 2584130 R 579112 CDS YP_002811137.1 227082586 7773647 complement(2584597..2585562) 1 NC_012578.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2585562 rseB 7773647 rseB Vibrio cholerae M66-2 periplasmic negative regulator of sigmaE YP_002811137.1 2584597 R 579112 CDS YP_002811138.1 227082587 7773648 complement(2585559..2586197) 1 NC_012578.1 sigma-E factor negative regulatory protein RseA 2586197 rseA 7773648 rseA Vibrio cholerae M66-2 sigma-E factor negative regulatory protein RseA YP_002811138.1 2585559 R 579112 CDS YP_002811139.1 227082588 7773649 complement(2586211..2586783) 1 NC_012578.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2586783 rpoE 7773649 rpoE Vibrio cholerae M66-2 RNA polymerase sigma factor RpoE YP_002811139.1 2586211 R 579112 CDS YP_002811140.1 227082589 7773650 complement(2587114..2587311) 1 NC_012578.1 hypothetical protein 2587311 7773650 VCM66_2391 Vibrio cholerae M66-2 hypothetical protein YP_002811140.1 2587114 R 579112 CDS YP_002811141.1 227082590 7773651 2587243..2588895 1 NC_012578.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2588895 nadB 7773651 nadB Vibrio cholerae M66-2 L-aspartate oxidase YP_002811141.1 2587243 D 579112 CDS YP_002811142.1 227082591 7773652 complement(2588920..2589366) 1 NC_012578.1 hypothetical protein 2589366 7773652 VCM66_2393 Vibrio cholerae M66-2 hypothetical protein YP_002811142.1 2588920 R 579112 CDS YP_002811143.1 227082592 7773653 complement(2589314..2589574) 1 NC_012578.1 hypothetical protein 2589574 7773653 VCM66_2394 Vibrio cholerae M66-2 hypothetical protein YP_002811143.1 2589314 R 579112 CDS YP_002811144.1 227082593 7773654 2589727..2590698 1 NC_012578.1 hypothetical protein 2590698 7773654 VCM66_2395 Vibrio cholerae M66-2 hypothetical protein YP_002811144.1 2589727 D 579112 CDS YP_002811145.1 227082594 7773655 2591305..2591538 1 NC_012578.1 hypothetical protein 2591538 7773655 VCM66_2396 Vibrio cholerae M66-2 hypothetical protein YP_002811145.1 2591305 D 579112 CDS YP_002811146.1 227082595 7773656 complement(2591639..2592868) 1 NC_012578.1 catalyzes the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone from 2-octaprenyl-6-methoxyphenol; 2-octaprenyl-6-methoxyphenol hydroxylase 2592868 visC 7773656 visC Vibrio cholerae M66-2 2-octaprenyl-6-methoxyphenol hydroxylase YP_002811146.1 2591639 R 579112 CDS YP_002811147.1 227082596 7773657 complement(2592880..2594088) 1 NC_012578.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 2594088 ubiH 7773657 ubiH Vibrio cholerae M66-2 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002811147.1 2592880 R 579112 CDS YP_002811148.1 227082597 7773658 complement(2594109..2594684) 1 NC_012578.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 2594684 7773658 VCM66_2399 Vibrio cholerae M66-2 hypothetical protein YP_002811148.1 2594109 R 579112 CDS YP_002811149.1 227082598 7773659 2594926..2595234 1 NC_012578.1 hypothetical protein 2595234 7773659 VCM66_2400 Vibrio cholerae M66-2 hypothetical protein YP_002811149.1 2594926 D 579112 CDS YP_002811150.1 227082599 7773660 2595434..2596018 1 NC_012578.1 hypothetical protein 2596018 7773660 VCM66_2401 Vibrio cholerae M66-2 hypothetical protein YP_002811150.1 2595434 D 579112 CDS YP_002811151.1 227082600 7773661 2596128..2596784 1 NC_012578.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2596784 rpiA 7773661 rpiA Vibrio cholerae M66-2 ribose-5-phosphate isomerase A YP_002811151.1 2596128 D 579112 CDS YP_002811152.1 227082601 7773662 2597038..2598267 1 NC_012578.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2598267 serA 7773662 serA Vibrio cholerae M66-2 D-3-phosphoglycerate dehydrogenase YP_002811152.1 2597038 D 579112 CDS YP_002811153.1 227082602 7773663 complement(2598499..2598993) 1 NC_012578.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 2598993 ilvH 7773663 ilvH Vibrio cholerae M66-2 acetolactate synthase 3 regulatory subunit YP_002811153.1 2598499 R 579112 CDS YP_002811154.1 227082603 7773664 complement(2598995..2600716) 1 NC_012578.1 acetolactate synthase 3 catalytic subunit 2600716 ilvI 7773664 ilvI Vibrio cholerae M66-2 acetolactate synthase 3 catalytic subunit YP_002811154.1 2598995 R 579112 CDS YP_002811155.1 227082604 7773665 complement(2601201..2603006) 1 NC_012578.1 putative long-chain-fatty-acid--CoA ligase 2603006 7773665 VCM66_2406 Vibrio cholerae M66-2 putative long-chain-fatty-acid--CoA ligase YP_002811155.1 2601201 R 579112 CDS YP_002811156.1 227082605 7773666 complement(2603183..2604148) 1 NC_012578.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 2604148 leuO 7773666 leuO Vibrio cholerae M66-2 leucine transcriptional activator YP_002811156.1 2603183 R 579112 CDS YP_002811157.1 227082606 7773667 complement(2604166..2604267) 1 NC_012578.1 hypothetical protein 2604267 7773667 VCM66_2408 Vibrio cholerae M66-2 hypothetical protein YP_002811157.1 2604166 R 579112 CDS YP_002811158.1 227082607 7773668 complement(2604448..2605536) 1 NC_012578.1 hypothetical protein 2605536 7773668 VCM66_2409 Vibrio cholerae M66-2 hypothetical protein YP_002811158.1 2604448 R 579112 CDS YP_002811159.1 227082608 7773669 complement(2605533..2606069) 1 NC_012578.1 hypothetical protein 2606069 7773669 VCM66_2410 Vibrio cholerae M66-2 hypothetical protein YP_002811159.1 2605533 R 579112 CDS YP_002811160.1 227082609 7773670 complement(2606196..2606831) 1 NC_012578.1 TetR family transcriptional regulator 2606831 7773670 VCM66_2411 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002811160.1 2606196 R 579112 CDS YP_002811161.1 227082610 7773671 2607214..2608764 1 NC_012578.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2608764 leuA 7773671 leuA Vibrio cholerae M66-2 2-isopropylmalate synthase YP_002811161.1 2607214 D 579112 CDS YP_002811162.1 227082611 7773672 2608876..2609967 1 NC_012578.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2609967 leuB 7773672 leuB Vibrio cholerae M66-2 3-isopropylmalate dehydrogenase YP_002811162.1 2608876 D 579112 CDS YP_002811163.1 227082612 7773673 2610025..2611428 1 NC_012578.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2611428 leuC 7773673 leuC Vibrio cholerae M66-2 isopropylmalate isomerase large subunit YP_002811163.1 2610025 D 579112 CDS YP_002811164.1 227082613 7773674 2611444..2612046 1 NC_012578.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2612046 leuD 7773674 leuD Vibrio cholerae M66-2 isopropylmalate isomerase small subunit YP_002811164.1 2611444 D 579112 CDS YP_002811165.1 227082614 7773675 2612147..2612938 1 NC_012578.1 hypothetical protein 2612938 7773675 VCM66_2416 Vibrio cholerae M66-2 hypothetical protein YP_002811165.1 2612147 D 579112 CDS YP_002811166.1 227082615 7773973 complement(2618623..2618715) 1 NC_012578.1 hypothetical protein 2618715 7773973 VCM66_2418 Vibrio cholerae M66-2 hypothetical protein YP_002811166.1 2618623 R 579112 CDS YP_002811167.1 227082616 7773677 complement(2618958..2620211) 1 NC_012578.1 rpfG-type response regulator 2620211 7773677 VCM66_2419 Vibrio cholerae M66-2 rpfG-type response regulator YP_002811167.1 2618958 R 579112 CDS YP_002811168.1 227082617 7774043 2620642..2621124 1 NC_012578.1 hypothetical protein 2621124 7774043 VCM66_2420 Vibrio cholerae M66-2 hypothetical protein YP_002811168.1 2620642 D 579112 CDS YP_002811169.1 227082618 7773679 complement(2621230..2622300) 1 NC_012578.1 putative Inner membrane protein 2622300 7773679 VCM66_2421 Vibrio cholerae M66-2 putative Inner membrane protein YP_002811169.1 2621230 R 579112 CDS YP_002811170.1 227082619 7773680 complement(2622304..2623404) 1 NC_012578.1 hypothetical protein 2623404 7773680 VCM66_2422 Vibrio cholerae M66-2 hypothetical protein YP_002811170.1 2622304 R 579112 CDS YP_002811171.1 227082620 7773681 2623598..2625109 1 NC_012578.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 2625109 pepA 7773681 pepA Vibrio cholerae M66-2 leucyl aminopeptidase YP_002811171.1 2623598 D 579112 CDS YP_002811172.1 227082621 7773682 2625193..2625642 1 NC_012578.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 2625642 holC 7773682 holC Vibrio cholerae M66-2 DNA polymerase III subunit chi YP_002811172.1 2625193 D 579112 CDS YP_002811173.1 227082622 7773683 2625736..2628597 1 NC_012578.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2628597 valS 7773683 valS Vibrio cholerae M66-2 valyl-tRNA synthetase YP_002811173.1 2625736 D 579112 CDS YP_002811174.1 227082623 7773684 complement(2628675..2629652) 1 NC_012578.1 2-hydroxyacid dehydrogenase family protein 2629652 7773684 VCM66_2426 Vibrio cholerae M66-2 2-hydroxyacid dehydrogenase family protein YP_002811174.1 2628675 R 579112 CDS YP_002811175.1 227082624 7773685 complement(2629692..2630429) 1 NC_012578.1 ribosomal large subunit pseudouridine synthase A 2630429 rluA-1 7773685 rluA-1 Vibrio cholerae M66-2 ribosomal large subunit pseudouridine synthase A YP_002811175.1 2629692 R 579112 CDS YP_002811176.1 227082625 7773686 complement(2630526..2633435) 1 NC_012578.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 2633435 hepA 7773686 hepA Vibrio cholerae M66-2 ATP-dependent helicase HepA YP_002811176.1 2630526 R 579112 CDS YP_002811177.1 227082626 7773687 2633857..2635233 1 NC_012578.1 PhoH-like protein 2635233 7773687 VCM66_2429 Vibrio cholerae M66-2 PhoH-like protein YP_002811177.1 2633857 D 579112 CDS YP_002811178.1 227082627 7773688 2635383..2636387 1 NC_012578.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2636387 argF 7773688 argF Vibrio cholerae M66-2 ornithine carbamoyltransferase YP_002811178.1 2635383 D 579112 CDS YP_002811179.1 227082628 7773689 2636485..2636580 1 NC_012578.1 hypothetical protein 2636580 7773689 VCM66_2431 Vibrio cholerae M66-2 hypothetical protein YP_002811179.1 2636485 D 579112 CDS YP_002811180.1 227082629 7773690 2636574..2637566 1 NC_012578.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 2637566 pyrB 7773690 pyrB Vibrio cholerae M66-2 aspartate carbamoyltransferase catalytic subunit YP_002811180.1 2636574 D 579112 CDS YP_002811181.1 227082630 7773691 2637578..2638045 1 NC_012578.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 2638045 pyrI 7773691 pyrI Vibrio cholerae M66-2 aspartate carbamoyltransferase regulatory subunit YP_002811181.1 2637578 D 579112 CDS YP_002811182.1 227082631 7773692 2638150..2638539 1 NC_012578.1 hypothetical protein 2638539 7773692 VCM66_2434 Vibrio cholerae M66-2 hypothetical protein YP_002811182.1 2638150 D 579112 CDS YP_002811183.1 227082632 7773693 complement(2638620..2639405) 1 NC_012578.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 2639405 plsC 7773693 plsC Vibrio cholerae M66-2 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002811183.1 2638620 R 579112 CDS YP_002811184.1 227082633 7773694 complement(2639427..2640686) 1 NC_012578.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2640686 murA 7773694 murA Vibrio cholerae M66-2 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002811184.1 2639427 R 579112 CDS YP_002811185.1 227082634 7773695 complement(2640694..2640948) 1 NC_012578.1 BolA/YrbA family protein 2640948 7773695 VCM66_2437 Vibrio cholerae M66-2 BolA/YrbA family protein YP_002811185.1 2640694 R 579112 CDS YP_002811186.1 227082635 7773696 complement(2640941..2641270) 1 NC_012578.1 putative anti-sigma B factor antagonist 2641270 7773696 VCM66_2438 Vibrio cholerae M66-2 putative anti-sigma B factor antagonist YP_002811186.1 2640941 R 579112 CDS YP_002811187.1 227082636 7773697 complement(2641267..2641908) 1 NC_012578.1 hypothetical protein 2641908 7773697 VCM66_2439 Vibrio cholerae M66-2 hypothetical protein YP_002811187.1 2641267 R 579112 CDS YP_002811188.1 227082637 7773698 complement(2641909..2642400) 1 NC_012578.1 hypothetical protein 2642400 7773698 VCM66_2440 Vibrio cholerae M66-2 hypothetical protein YP_002811188.1 2641909 R 579112 CDS YP_002811189.1 227082638 7773699 complement(2642403..2643179) 1 NC_012578.1 hypothetical protein 2643179 7773699 VCM66_2441 Vibrio cholerae M66-2 hypothetical protein YP_002811189.1 2642403 R 579112 CDS YP_002811190.1 227082639 7773700 complement(2643184..2643987) 1 NC_012578.1 ABC transporter ATP-binding protein 2643987 7773700 VCM66_2442 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002811190.1 2643184 R 579112 CDS YP_002811191.1 227082640 7773701 complement(2644115..2644306) 1 NC_012578.1 hypothetical protein 2644306 7773701 VCM66_2443 Vibrio cholerae M66-2 hypothetical protein YP_002811191.1 2644115 R 579112 CDS YP_002811192.1 227082641 7773702 2644544..2645542 1 NC_012578.1 putative Inner membrane protein 2645542 7773702 VCM66_2444 Vibrio cholerae M66-2 putative Inner membrane protein YP_002811192.1 2644544 D 579112 CDS YP_002811193.1 227082642 7773703 2645592..2646572 1 NC_012578.1 Arabinose 5-phosphate isomerase 2646572 7773703 VCM66_2445 Vibrio cholerae M66-2 Arabinose 5-phosphate isomerase YP_002811193.1 2645592 D 579112 CDS YP_002811194.1 227082643 7773704 2646572..2647129 1 NC_012578.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 2647129 7773704 VCM66_2446 Vibrio cholerae M66-2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002811194.1 2646572 D 579112 CDS YP_002811195.1 227082644 7773705 2647126..2647689 1 NC_012578.1 hypothetical protein 2647689 7773705 VCM66_2447 Vibrio cholerae M66-2 hypothetical protein YP_002811195.1 2647126 D 579112 CDS YP_002811196.1 227082645 7773706 2647625..2648164 1 NC_012578.1 hypothetical protein 2648164 7773706 VCM66_2448 Vibrio cholerae M66-2 hypothetical protein YP_002811196.1 2647625 D 579112 CDS YP_002811197.1 227082646 7773707 2648167..2648892 1 NC_012578.1 ABC transporter ATP-binding protein 2648892 7773707 VCM66_2449 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002811197.1 2648167 D 579112 CDS YP_002811198.1 227082647 7773708 2648948..2650411 1 NC_012578.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 2650411 rpoN 7773708 rpoN Vibrio cholerae M66-2 RNA polymerase factor sigma-54 YP_002811198.1 2648948 D 579112 CDS YP_002811199.1 227082648 7773709 2650436..2650723 1 NC_012578.1 putative sigma-54 modulation protein 2650723 7773709 VCM66_2451 Vibrio cholerae M66-2 putative sigma-54 modulation protein YP_002811199.1 2650436 D 579112 CDS YP_002811200.1 227082649 7773710 2650726..2651172 1 NC_012578.1 PTS system, nitrogen regulatory IIA component 2651172 ptsN 7773710 ptsN Vibrio cholerae M66-2 PTS system, nitrogen regulatory IIA component YP_002811200.1 2650726 D 579112 CDS YP_002811201.1 227082650 7773711 2651185..2652045 1 NC_012578.1 hypothetical protein 2652045 7773711 VCM66_2453 Vibrio cholerae M66-2 hypothetical protein YP_002811201.1 2651185 D 579112 CDS YP_002811202.1 227082651 7773712 2652054..2652332 1 NC_012578.1 phosphocarrier protein NPr 2652332 ptsO 7773712 ptsO Vibrio cholerae M66-2 phosphocarrier protein NPr YP_002811202.1 2652054 D 579112 CDS YP_002811203.1 227082652 7773713 2652493..2653854 1 NC_012578.1 magnesium transporter 2653854 mgtE-2 7773713 mgtE-2 Vibrio cholerae M66-2 magnesium transporter YP_002811203.1 2652493 D 579112 CDS YP_002811204.1 227082653 7773714 complement(2653926..2655269) 1 NC_012578.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 2655269 pmbA 7773714 pmbA Vibrio cholerae M66-2 peptidase PmbA YP_002811204.1 2653926 R 579112 CDS YP_002811205.1 227082654 7773715 2655368..2655949 1 NC_012578.1 hypothetical protein 2655949 7773715 VCM66_2457 Vibrio cholerae M66-2 hypothetical protein YP_002811205.1 2655368 D 579112 CDS YP_002811206.1 227082655 7773716 complement(2656052..2656786) 1 NC_012578.1 putative thiamine ABC transporter ATP-binding protein 2656786 7773716 VCM66_2458 Vibrio cholerae M66-2 putative thiamine ABC transporter ATP-binding protein YP_002811206.1 2656052 R 579112 CDS YP_002811207.1 227082656 7773717 complement(2656780..2658372) 1 NC_012578.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 2658372 thiP 7773717 thiP Vibrio cholerae M66-2 thiamine transporter membrane protein YP_002811207.1 2656780 R 579112 CDS YP_002811208.1 227082657 7773718 complement(2658382..2659374) 1 NC_012578.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 2659374 tbpA 7773718 tbpA Vibrio cholerae M66-2 thiamine transporter substrate binding subunit YP_002811208.1 2658382 R 579112 CDS YP_002811209.1 227082658 7773719 complement(2659244..2659636) 1 NC_012578.1 hypothetical protein 2659636 7773719 VCM66_2461 Vibrio cholerae M66-2 hypothetical protein YP_002811209.1 2659244 R 579112 CDS YP_002811210.1 227082659 7773720 complement(2659636..2660271) 1 NC_012578.1 aromatic acid decarboxylase 2660271 ubiX 7773720 ubiX Vibrio cholerae M66-2 aromatic acid decarboxylase YP_002811210.1 2659636 R 579112 CDS YP_002811211.1 227082660 7773721 complement(2660278..2661633) 1 NC_012578.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 2661633 mpl 7773721 mpl Vibrio cholerae M66-2 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002811211.1 2660278 R 579112 CDS YP_002811212.1 227082661 7773722 2661622..2661885 1 NC_012578.1 hypothetical protein 2661885 7773722 VCM66_2464 Vibrio cholerae M66-2 hypothetical protein YP_002811212.1 2661622 D 579112 CDS YP_002811213.1 227082662 7773723 2661939..2662949 1 NC_012578.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 2662949 fbp 7773723 fbp Vibrio cholerae M66-2 fructose-1,6-bisphosphatase YP_002811213.1 2661939 D 579112 CDS YP_002811214.1 227082663 7773724 2663119..2663649 1 NC_012578.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 2663649 ppa 7773724 ppa Vibrio cholerae M66-2 inorganic pyrophosphatase YP_002811214.1 2663119 D 579112 CDS YP_002811215.1 227082664 7773725 complement(2663709..2664056) 1 NC_012578.1 hypothetical protein 2664056 7773725 VCM66_2467 Vibrio cholerae M66-2 hypothetical protein YP_002811215.1 2663709 R 579112 CDS YP_002811216.1 227082665 7773726 complement(2664067..2667831) 1 NC_012578.1 hypothetical protein 2667831 7773726 VCM66_2468 Vibrio cholerae M66-2 hypothetical protein YP_002811216.1 2664067 R 579112 CDS YP_002811217.1 227082666 7773727 complement(2667828..2669576) 1 NC_012578.1 hypothetical protein 2669576 7773727 VCM66_2469 Vibrio cholerae M66-2 hypothetical protein YP_002811217.1 2667828 R 579112 CDS YP_002811218.1 227082667 7773728 2669722..2670360 1 NC_012578.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 2670360 msrA 7773728 msrA Vibrio cholerae M66-2 methionine sulfoxide reductase A YP_002811218.1 2669722 D 579112 CDS YP_002811219.1 227082668 7773729 2670442..2670993 1 NC_012578.1 hypothetical protein 2670993 7773729 VCM66_2471 Vibrio cholerae M66-2 hypothetical protein YP_002811219.1 2670442 D 579112 CDS YP_002811220.1 227082669 7773730 2671211..2671516 1 NC_012578.1 hypothetical protein 2671516 7773730 VCM66_2472 Vibrio cholerae M66-2 hypothetical protein YP_002811220.1 2671211 D 579112 CDS YP_002811221.1 227082670 7773731 2671565..2672293 1 NC_012578.1 hypothetical protein 2672293 7773731 VCM66_2473 Vibrio cholerae M66-2 hypothetical protein YP_002811221.1 2671565 D 579112 CDS YP_002811222.1 227082671 7773732 2672375..2673091 1 NC_012578.1 ABC transporter ATP-binding protein 2673091 7773732 VCM66_2474 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002811222.1 2672375 D 579112 CDS YP_002811223.1 227082672 7773733 2673082..2674347 1 NC_012578.1 hypothetical protein 2674347 7773733 VCM66_2475 Vibrio cholerae M66-2 hypothetical protein YP_002811223.1 2673082 D 579112 CDS YP_002811224.1 227082673 7773734 2674400..2674921 1 NC_012578.1 hypothetical protein 2674921 7773734 VCM66_2476 Vibrio cholerae M66-2 hypothetical protein YP_002811224.1 2674400 D 579112 CDS YP_002811225.1 227082674 7773735 2675232..2676131 1 NC_012578.1 hypothetical protein 2676131 7773735 VCM66_2477 Vibrio cholerae M66-2 hypothetical protein YP_002811225.1 2675232 D 579112 CDS YP_002811226.1 227082675 7773736 complement(2676204..2676851) 1 NC_012578.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 2676851 cysC 7773736 cysC Vibrio cholerae M66-2 adenylylsulfate kinase YP_002811226.1 2676204 R 579112 CDS YP_002811227.1 227082676 7773737 complement(2676862..2678292) 1 NC_012578.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 2678292 cysN 7773737 cysN Vibrio cholerae M66-2 sulfate adenylyltransferase subunit 1 YP_002811227.1 2676862 R 579112 CDS YP_002811228.1 227082677 7773738 complement(2678310..2679218) 1 NC_012578.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2679218 cysD 7773738 cysD Vibrio cholerae M66-2 sulfate adenylyltransferase subunit 2 YP_002811228.1 2678310 R 579112 CDS YP_002811229.1 227082678 7773739 complement(2679321..2680220) 1 NC_012578.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; uroporphyrin-III C-methyltransferase 2680220 cysG 7773739 cysG Vibrio cholerae M66-2 uroporphyrin-III C-methyltransferase YP_002811229.1 2679321 R 579112 CDS YP_002811230.1 227082679 7773740 2680421..2682466 1 NC_012578.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 2682466 cpdB 7773740 cpdB Vibrio cholerae M66-2 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_002811230.1 2680421 D 579112 CDS YP_002811231.1 227082680 7773741 2682586..2683155 1 NC_012578.1 hypothetical protein 2683155 7773741 VCM66_2483 Vibrio cholerae M66-2 hypothetical protein YP_002811231.1 2682586 D 579112 CDS YP_002811232.1 227082681 7773742 complement(2683158..2684540) 1 NC_012578.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 2684540 dbpA 7773742 dbpA Vibrio cholerae M66-2 ATP-dependent RNA helicase DbpA YP_002811232.1 2683158 R 579112 CDS YP_002811233.1 227082682 7773743 2684766..2685215 1 NC_012578.1 elaA protein 2685215 elaA 7773743 elaA Vibrio cholerae M66-2 elaA protein YP_002811233.1 2684766 D 579112 CDS YP_002811234.1 227082683 7773744 2685218..2686111 1 NC_012578.1 hypothetical protein 2686111 7773744 VCM66_2486 Vibrio cholerae M66-2 hypothetical protein YP_002811234.1 2685218 D 579112 CDS YP_002811235.1 227082684 7773745 complement(2686061..2686633) 1 NC_012578.1 hypothetical protein 2686633 7773745 VCM66_2487 Vibrio cholerae M66-2 hypothetical protein YP_002811235.1 2686061 R 579112 CDS YP_002811236.1 227082685 7773746 2686844..2687473 1 NC_012578.1 FKBP-type peptidyl-prolyl cis-trans isomerase 2687473 fklB 7773746 fklB Vibrio cholerae M66-2 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002811236.1 2686844 D 579112 CDS YP_002811237.1 227082686 7773747 2687609..2688091 1 NC_012578.1 hypothetical protein 2688091 7773747 VCM66_2489 Vibrio cholerae M66-2 hypothetical protein YP_002811237.1 2687609 D 579112 CDS YP_002811238.1 227082687 7773748 complement(2688235..2688621) 1 NC_012578.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2688621 rplQ 7773748 rplQ Vibrio cholerae M66-2 50S ribosomal protein L17 YP_002811238.1 2688235 R 579112 CDS YP_002811239.1 227082688 7773749 complement(2688648..2689640) 1 NC_012578.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2689640 rpoA 7773749 rpoA Vibrio cholerae M66-2 DNA-directed RNA polymerase subunit alpha YP_002811239.1 2688648 R 579112 CDS YP_002811240.1 227082689 7773750 complement(2689665..2690285) 1 NC_012578.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2690285 rpsD 7773750 rpsD Vibrio cholerae M66-2 30S ribosomal protein S4 YP_002811240.1 2689665 R 579112 CDS YP_002811241.1 227082690 7773751 complement(2690313..2690702) 1 NC_012578.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2690702 rpsK 7773751 rpsK Vibrio cholerae M66-2 30S ribosomal protein S11 YP_002811241.1 2690313 R 579112 CDS YP_002811242.1 227082691 7773752 complement(2690722..2691078) 1 NC_012578.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2691078 rpsM 7773752 rpsM Vibrio cholerae M66-2 30S ribosomal protein S13 YP_002811242.1 2690722 R 579112 CDS YP_002811243.1 227082692 7773753 complement(2691228..2691341) 1 NC_012578.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2691341 rpmJ 7773753 rpmJ Vibrio cholerae M66-2 50S ribosomal protein L36 YP_002811243.1 2691228 R 579112 CDS YP_002811244.1 227082693 7773754 complement(2691380..2692714) 1 NC_012578.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2692714 secY 7773754 secY Vibrio cholerae M66-2 preprotein translocase subunit SecY YP_002811244.1 2691380 R 579112 CDS YP_002811245.1 227082694 7773755 complement(2692735..2693169) 1 NC_012578.1 late assembly protein; 50S ribosomal protein L15 2693169 rplO 7773755 rplO Vibrio cholerae M66-2 50S ribosomal protein L15 YP_002811245.1 2692735 R 579112 CDS YP_002811246.1 227082695 7773756 complement(2693175..2693351) 1 NC_012578.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2693351 rpmD 7773756 rpmD Vibrio cholerae M66-2 50S ribosomal protein L30 YP_002811246.1 2693175 R 579112 CDS YP_002811247.1 227082696 7773757 complement(2693358..2693861) 1 NC_012578.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2693861 rpsE 7773757 rpsE Vibrio cholerae M66-2 30S ribosomal protein S5 YP_002811247.1 2693358 R 579112 CDS YP_002811248.1 227082697 7773758 complement(2693876..2694229) 1 NC_012578.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2694229 rplR 7773758 rplR Vibrio cholerae M66-2 50S ribosomal protein L18 YP_002811248.1 2693876 R 579112 CDS YP_002811249.1 227082698 7773759 complement(2694239..2694772) 1 NC_012578.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2694772 rplF 7773759 rplF Vibrio cholerae M66-2 50S ribosomal protein L6 YP_002811249.1 2694239 R 579112 CDS YP_002811250.1 227082699 7773760 complement(2694787..2695179) 1 NC_012578.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2695179 rpsH 7773760 rpsH Vibrio cholerae M66-2 30S ribosomal protein S8 YP_002811250.1 2694787 R 579112 CDS YP_002811251.1 227082700 7773761 complement(2695209..2695514) 1 NC_012578.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2695514 rpsN 7773761 rpsN Vibrio cholerae M66-2 30S ribosomal protein S14 YP_002811251.1 2695209 R 579112 CDS YP_002811252.1 227082701 7773762 complement(2695532..2696071) 1 NC_012578.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2696071 rplE 7773762 rplE Vibrio cholerae M66-2 50S ribosomal protein L5 YP_002811252.1 2695532 R 579112 CDS YP_002811253.1 227082702 7773763 complement(2696096..2696413) 1 NC_012578.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2696413 rplX 7773763 rplX Vibrio cholerae M66-2 50S ribosomal protein L24 YP_002811253.1 2696096 R 579112 CDS YP_002811254.1 227082703 7773764 complement(2696426..2696797) 1 NC_012578.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2696797 rplN 7773764 rplN Vibrio cholerae M66-2 50S ribosomal protein L14 YP_002811254.1 2696426 R 579112 CDS YP_002811255.1 227082704 7773765 complement(2696960..2697214) 1 NC_012578.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2697214 rpsQ 7773765 rpsQ Vibrio cholerae M66-2 30S ribosomal protein S17 YP_002811255.1 2696960 R 579112 CDS YP_002811256.1 227082705 7773766 complement(2697214..2697405) 1 NC_012578.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2697405 rpmC 7773766 rpmC Vibrio cholerae M66-2 50S ribosomal protein L29 YP_002811256.1 2697214 R 579112 CDS YP_002811257.1 227082706 7773767 complement(2697405..2697815) 1 NC_012578.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2697815 rplP 7773767 rplP Vibrio cholerae M66-2 50S ribosomal protein L16 YP_002811257.1 2697405 R 579112 CDS YP_002811258.1 227082707 7773768 complement(2697827..2698528) 1 NC_012578.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2698528 rpsC 7773768 rpsC Vibrio cholerae M66-2 30S ribosomal protein S3 YP_002811258.1 2697827 R 579112 CDS YP_002811259.1 227082708 7773769 complement(2698548..2698880) 1 NC_012578.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2698880 rplV 7773769 rplV Vibrio cholerae M66-2 50S ribosomal protein L22 YP_002811259.1 2698548 R 579112 CDS YP_002811260.1 227082709 7773770 complement(2698891..2699169) 1 NC_012578.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2699169 rpsS 7773770 rpsS Vibrio cholerae M66-2 30S ribosomal protein S19 YP_002811260.1 2698891 R 579112 CDS YP_002811261.1 227082710 7773771 complement(2699190..2700014) 1 NC_012578.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2700014 rplB 7773771 rplB Vibrio cholerae M66-2 50S ribosomal protein L2 YP_002811261.1 2699190 R 579112 CDS YP_002811262.1 227082711 7773772 complement(2700031..2700333) 1 NC_012578.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2700333 rplW 7773772 rplW Vibrio cholerae M66-2 50S ribosomal protein L23 YP_002811262.1 2700031 R 579112 CDS YP_002811263.1 227082712 7773773 complement(2700330..2700932) 1 NC_012578.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2700932 rplD 7773773 rplD Vibrio cholerae M66-2 50S ribosomal protein L4 YP_002811263.1 2700330 R 579112 CDS YP_002811264.1 227082713 7773774 complement(2700949..2701578) 1 NC_012578.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2701578 rplC 7773774 rplC Vibrio cholerae M66-2 50S ribosomal protein L3 YP_002811264.1 2700949 R 579112 CDS YP_002811265.1 227082714 7773775 complement(2701593..2701904) 1 NC_012578.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2701904 rpsJ 7773775 rpsJ Vibrio cholerae M66-2 30S ribosomal protein S10 YP_002811265.1 2701593 R 579112 CDS YP_002811266.1 227082715 7773776 complement(2702375..2703118) 1 NC_012578.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 2703118 7773776 VCM66_2518 Vibrio cholerae M66-2 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002811266.1 2702375 R 579112 CDS YP_002811267.1 227082716 7773777 complement(2703126..2705591) 1 NC_012578.1 ribonuclease R 2705591 vacB 7773777 vacB Vibrio cholerae M66-2 ribonuclease R YP_002811267.1 2703126 R 579112 CDS YP_002811268.1 227082717 7773778 2705735..2707603 1 NC_012578.1 putative Inner membrane protein 2707603 7773778 VCM66_2520 Vibrio cholerae M66-2 putative Inner membrane protein YP_002811268.1 2705735 D 579112 CDS YP_002811269.1 227082718 7773779 complement(2707630..2708265) 1 NC_012578.1 sodium-type flagellar protein MotX 2708265 motX 7773779 motX Vibrio cholerae M66-2 sodium-type flagellar protein MotX YP_002811269.1 2707630 R 579112 CDS YP_002811270.1 227082719 7773780 complement(2708473..2709771) 1 NC_012578.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 2709771 purA 7773780 purA Vibrio cholerae M66-2 adenylosuccinate synthetase YP_002811270.1 2708473 R 579112 CDS YP_002811271.1 227082720 7773781 complement(2709899..2710879) 1 NC_012578.1 putative asparaginase 2710879 7773781 VCM66_2523 Vibrio cholerae M66-2 putative asparaginase YP_002811271.1 2709899 R 579112 CDS YP_002811272.1 227082721 7773782 complement(2711042..2711647) 1 NC_012578.1 FKBP-type peptidyl-prolyl cis-trans isomerase 2711647 slyD 7773782 slyD Vibrio cholerae M66-2 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002811272.1 2711042 R 579112 CDS YP_002811273.1 227082722 7773783 complement(2711739..2711939) 1 NC_012578.1 hypothetical protein 2711939 7773783 VCM66_2525 Vibrio cholerae M66-2 hypothetical protein YP_002811273.1 2711739 R 579112 CDS YP_002811274.1 227082723 7773784 complement(2711949..2713919) 1 NC_012578.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 2713919 kefB 7773784 kefB Vibrio cholerae M66-2 glutathione-regulated potassium-efflux system protein KefB YP_002811274.1 2711949 R 579112 CDS YP_002811275.1 227082724 7773785 complement(2713732..2714322) 1 NC_012578.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 2714322 7773785 VCM66_2527 Vibrio cholerae M66-2 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002811275.1 2713732 R 579112 CDS YP_002811276.1 227082725 7773786 2714368..2716362 1 NC_012578.1 ABC transporter ATP-binding protein 2716362 7773786 VCM66_2528 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002811276.1 2714368 D 579112 CDS YP_002811277.1 227082726 7773787 2716363..2716848 1 NC_012578.1 hypothetical protein 2716848 7773787 VCM66_2529 Vibrio cholerae M66-2 hypothetical protein YP_002811277.1 2716363 D 579112 CDS YP_002811278.1 227082727 7773788 2716845..2717834 1 NC_012578.1 putative hydrolase 2717834 7773788 VCM66_2530 Vibrio cholerae M66-2 putative hydrolase YP_002811278.1 2716845 D 579112 CDS YP_002811279.1 227082728 7773789 2717962..2718171 1 NC_012578.1 hypothetical protein 2718171 7773789 VCM66_2532 Vibrio cholerae M66-2 hypothetical protein YP_002811279.1 2717962 D 579112 CDS YP_002811280.1 227082729 7773790 2718268..2719137 1 NC_012578.1 phosphoribulokinase 2719137 prkB 7773790 prkB Vibrio cholerae M66-2 phosphoribulokinase YP_002811280.1 2718268 D 579112 CDS YP_002811281.1 227082730 7773791 2719380..2720012 1 NC_012578.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 2720012 7773791 VCM66_2534 Vibrio cholerae M66-2 cAMP-regulatory protein YP_002811281.1 2719380 D 579112 CDS YP_002811282.1 227082731 7773792 complement(2720091..2720882) 1 NC_012578.1 hypothetical protein 2720882 7773792 VCM66_2535 Vibrio cholerae M66-2 hypothetical protein YP_002811282.1 2720091 R 579112 CDS YP_002811283.1 227082732 7773793 complement(2721025..2722482) 1 NC_012578.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2722482 astD 7773793 astD Vibrio cholerae M66-2 succinylglutamic semialdehyde dehydrogenase YP_002811283.1 2721025 R 579112 CDS YP_002811284.1 227082733 7773794 complement(2722492..2723550) 1 NC_012578.1 putative arginine/ornithine succinyltransferase 2723550 7773794 VCM66_2537 Vibrio cholerae M66-2 putative arginine/ornithine succinyltransferase YP_002811284.1 2722492 R 579112 CDS YP_002811285.1 227082734 7773795 complement(2723650..2724861) 1 NC_012578.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 2724861 argD 7773795 argD Vibrio cholerae M66-2 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_002811285.1 2723650 R 579112 CDS YP_002811286.1 227082735 7773796 complement(2725259..2725840) 1 NC_012578.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 2725840 pabA 7773796 pabA Vibrio cholerae M66-2 para-aminobenzoate synthase component II YP_002811286.1 2725259 R 579112 CDS YP_002811287.1 227082736 7773797 2726094..2727506 1 NC_012578.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 2727506 rimO 7773797 rimO Vibrio cholerae M66-2 ribosomal protein S12 methylthiotransferase YP_002811287.1 2726094 D 579112 CDS YP_002811288.1 227082737 7773798 complement(2727583..2730192) 1 NC_012578.1 extracellular nuclease-like protein 2730192 7773798 VCM66_2541 Vibrio cholerae M66-2 extracellular nuclease-like protein YP_002811288.1 2727583 R 579112 CDS YP_002811289.1 227082738 7773799 complement(2730462..2731235) 1 NC_012578.1 hypothetical protein 2731235 7773799 VCM66_2542 Vibrio cholerae M66-2 hypothetical protein YP_002811289.1 2730462 R 579112 CDS YP_002811290.1 227082739 7773800 complement(2731391..2732488) 1 NC_012578.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 2732488 trpS 7773800 trpS Vibrio cholerae M66-2 tryptophanyl-tRNA synthetase YP_002811290.1 2731391 R 579112 CDS YP_002811291.1 227082740 7773801 complement(2732535..2733215) 1 NC_012578.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 2733215 gph 7773801 gph Vibrio cholerae M66-2 phosphoglycolate phosphatase YP_002811291.1 2732535 R 579112 CDS YP_002811292.1 227082741 7773802 complement(2733235..2733945) 1 NC_012578.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2733945 rpe 7773802 rpe Vibrio cholerae M66-2 ribulose-phosphate 3-epimerase YP_002811292.1 2733235 R 579112 CDS YP_002811293.1 227082742 7773803 complement(2734036..2734869) 1 NC_012578.1 DNA adenine methylase 2734869 dam 7773803 dam Vibrio cholerae M66-2 DNA adenine methylase YP_002811293.1 2734036 R 579112 CDS YP_002811294.1 227082743 7773804 complement(2734939..2736414) 1 NC_012578.1 DamX-like protein 2736414 7773804 VCM66_2547 Vibrio cholerae M66-2 DamX-like protein YP_002811294.1 2734939 R 579112 CDS YP_002811295.1 227082744 7773805 complement(2736469..2737569) 1 NC_012578.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 2737569 aroB 7773805 aroB Vibrio cholerae M66-2 3-dehydroquinate synthase YP_002811295.1 2736469 R 579112 CDS YP_002811296.1 227082745 7773806 complement(2737582..2738106) 1 NC_012578.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 2738106 aroK 7773806 aroK Vibrio cholerae M66-2 shikimate kinase I YP_002811296.1 2737582 R 579112 CDS YP_002811297.1 227082746 7773807 complement(2738293..2740029) 1 NC_012578.1 fimbrial assembly protein 2740029 pilQ 7773807 pilQ Vibrio cholerae M66-2 fimbrial assembly protein YP_002811297.1 2738293 R 579112 CDS YP_002811298.1 227082747 7773808 complement(2740034..2740552) 1 NC_012578.1 putative fimbrial assembly protein PilP 2740552 7773808 VCM66_2551 Vibrio cholerae M66-2 putative fimbrial assembly protein PilP YP_002811298.1 2740034 R 579112 CDS YP_002811299.1 227082748 7773809 complement(2740542..2741141) 1 NC_012578.1 putative fimbrial assembly protein PilO 2741141 7773809 VCM66_2552 Vibrio cholerae M66-2 putative fimbrial assembly protein PilO YP_002811299.1 2740542 R 579112 CDS YP_002811300.1 227082749 7773810 complement(2741125..2741715) 1 NC_012578.1 putative fimbrial assembly protein PilN 2741715 7773810 VCM66_2553 Vibrio cholerae M66-2 putative fimbrial assembly protein PilN YP_002811300.1 2741125 R 579112 CDS YP_002811301.1 227082750 7773811 complement(2741699..2742715) 1 NC_012578.1 putative fimbrial assembly protein PilM 2742715 7773811 VCM66_2554 Vibrio cholerae M66-2 putative fimbrial assembly protein PilM YP_002811301.1 2741699 R 579112 CDS YP_002811302.1 227082751 7773812 2742828..2745335 1 NC_012578.1 penicillin-binding protein 1A 2745335 mrcA 7773812 mrcA Vibrio cholerae M66-2 penicillin-binding protein 1A YP_002811302.1 2742828 D 579112 CDS YP_002811303.1 227082752 7773813 complement(2745409..2746302) 1 NC_012578.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 2746302 7773813 VCM66_2556 Vibrio cholerae M66-2 DNA-binding transcriptional regulator OxyR YP_002811303.1 2745409 R 579112 CDS YP_002811304.1 227082753 7773814 2746430..2747173 1 NC_012578.1 peroxiredoxin family protein/glutaredoxin 2747173 7773814 VCM66_2557 Vibrio cholerae M66-2 peroxiredoxin family protein/glutaredoxin YP_002811304.1 2746430 D 579112 CDS YP_002811305.1 227082754 7773815 2747245..2748699 1 NC_012578.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2748699 7773815 VCM66_2558 Vibrio cholerae M66-2 dihydrolipoamide dehydrogenase YP_002811305.1 2747245 D 579112 CDS YP_002811306.1 227082755 7773816 complement(2748696..2748803) 1 NC_012578.1 hypothetical protein 2748803 7773816 VCM66_2559 Vibrio cholerae M66-2 hypothetical protein YP_002811306.1 2748696 R 579112 CDS YP_002811307.1 227082756 7773817 2748925..2749188 1 NC_012578.1 hypothetical protein 2749188 7773817 VCM66_2560 Vibrio cholerae M66-2 hypothetical protein YP_002811307.1 2748925 D 579112 CDS YP_002811308.1 227082757 7773818 complement(2749439..2750815) 1 NC_012578.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 2750815 argH 7773818 argH Vibrio cholerae M66-2 argininosuccinate lyase YP_002811308.1 2749439 R 579112 CDS YP_002811309.1 227082758 7773819 complement(2751048..2752262) 1 NC_012578.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 2752262 argG 7773819 argG Vibrio cholerae M66-2 argininosuccinate synthase YP_002811309.1 2751048 R 579112 CDS YP_002811310.1 227082759 7773820 complement(2752338..2753126) 1 NC_012578.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 2753126 argB 7773820 argB Vibrio cholerae M66-2 acetylglutamate kinase YP_002811310.1 2752338 R 579112 CDS YP_002811311.1 227082760 7773821 complement(2753136..2754176) 1 NC_012578.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 2754176 argC 7773821 argC Vibrio cholerae M66-2 N-acetyl-gamma-glutamyl-phosphate reductase YP_002811311.1 2753136 R 579112 CDS YP_002811312.1 227082761 7773822 2754293..2755429 1 NC_012578.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 2755429 argE 7773822 argE Vibrio cholerae M66-2 acetylornithine deacetylase YP_002811312.1 2754293 D 579112 CDS YP_002811313.1 227082762 7773823 2755603..2758266 1 NC_012578.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 2758266 ppc 7773823 ppc Vibrio cholerae M66-2 phosphoenolpyruvate carboxylase YP_002811313.1 2755603 D 579112 CDS YP_002811314.1 227082763 7773824 2758625..2759164 1 NC_012578.1 hypothetical protein 2759164 aphA 7773824 aphA Vibrio cholerae M66-2 hypothetical protein YP_002811314.1 2758625 D 579112 CDS YP_002811315.1 227082764 7773825 2759113..2759241 1 NC_012578.1 hypothetical protein 2759241 7773825 VCM66_2568 Vibrio cholerae M66-2 hypothetical protein YP_002811315.1 2759113 D 579112 CDS YP_002811316.1 227082765 7773826 complement(2759280..2760101) 1 NC_012578.1 catalyzes the O-acetylation of serine; serine acetyltransferase 2760101 cysE 7773826 cysE Vibrio cholerae M66-2 serine acetyltransferase YP_002811316.1 2759280 R 579112 CDS YP_002811317.1 227082766 7773827 2759988..2760299 1 NC_012578.1 hypothetical protein 2760299 7773827 VCM66_2570 Vibrio cholerae M66-2 hypothetical protein YP_002811317.1 2759988 D 579112 CDS YP_002811318.1 227082767 7773828 complement(2760174..2761208) 1 NC_012578.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2761208 gpsA 7773828 gpsA Vibrio cholerae M66-2 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002811318.1 2760174 R 579112 CDS YP_002811319.1 227082768 7773829 2761341..2761511 1 NC_012578.1 hypothetical protein 2761511 7773829 VCM66_2572 Vibrio cholerae M66-2 hypothetical protein YP_002811319.1 2761341 D 579112 CDS YP_002811320.1 227082769 7773830 complement(2761398..2761862) 1 NC_012578.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 2761862 secB 7773830 secB Vibrio cholerae M66-2 preprotein translocase subunit SecB YP_002811320.1 2761398 R 579112 CDS YP_002811321.1 227082770 7773831 complement(2762029..2762463) 1 NC_012578.1 hypothetical protein 2762463 7773831 VCM66_2574 Vibrio cholerae M66-2 hypothetical protein YP_002811321.1 2762029 R 579112 CDS YP_002811322.1 227082771 7773832 complement(2762593..2763642) 1 NC_012578.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 2763642 yjeA 7773832 yjeA Vibrio cholerae M66-2 lysyl-tRNA synthetase YP_002811322.1 2762593 R 579112 CDS YP_002811323.1 227082772 7773833 2763876..2765684 1 NC_012578.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 2765684 frdA 7773833 frdA Vibrio cholerae M66-2 fumarate reductase flavoprotein subunit YP_002811323.1 2763876 D 579112 CDS YP_002811324.1 227082773 7773834 2765684..2766442 1 NC_012578.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 2766442 frdB 7773834 frdB Vibrio cholerae M66-2 fumarate reductase iron-sulfur subunit YP_002811324.1 2765684 D 579112 CDS YP_002811325.1 227082774 7773835 2766445..2766828 1 NC_012578.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 2766828 frdC 7773835 frdC Vibrio cholerae M66-2 fumarate reductase subunit C YP_002811325.1 2766445 D 579112 CDS YP_002811326.1 227082775 7773836 2766809..2767201 1 NC_012578.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 2767201 frdD 7773836 frdD Vibrio cholerae M66-2 fumarate reductase subunit D YP_002811326.1 2766809 D 579112 CDS YP_002811327.1 227082776 7773837 complement(2767315..2767881) 1 NC_012578.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2767881 efp 7773837 efp Vibrio cholerae M66-2 elongation factor P YP_002811327.1 2767315 R 579112 CDS YP_002811328.1 227082777 7773838 2767914..2768936 1 NC_012578.1 hypothetical protein 2768936 7773838 VCM66_2581 Vibrio cholerae M66-2 hypothetical protein YP_002811328.1 2767914 D 579112 CDS YP_002811329.1 227082778 7773839 complement(2768973..2769548) 1 NC_012578.1 hypothetical protein 2769548 7773839 VCM66_2582 Vibrio cholerae M66-2 hypothetical protein YP_002811329.1 2768973 R 579112 CDS YP_002811330.1 227082779 7773840 complement(2769571..2769675) 1 NC_012578.1 hypothetical protein 2769675 7773840 VCM66_2583 Vibrio cholerae M66-2 hypothetical protein YP_002811330.1 2769571 R 579112 CDS YP_002811331.1 227082780 7773841 complement(2769744..2771378) 1 NC_012578.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 2771378 groEL 7773841 groEL Vibrio cholerae M66-2 chaperonin GroEL YP_002811331.1 2769744 R 579112 CDS YP_002811332.1 227082781 7773842 complement(2771432..2771722) 1 NC_012578.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 2771722 groES 7773842 groES Vibrio cholerae M66-2 co-chaperonin GroES YP_002811332.1 2771432 R 579112 CDS YP_002811333.1 227082782 7773843 2772082..2772699 1 NC_012578.1 hypothetical protein 2772699 7773843 VCM66_2586 Vibrio cholerae M66-2 hypothetical protein YP_002811333.1 2772082 D 579112 CDS YP_002811334.1 227082783 7773844 2772838..2773197 1 NC_012578.1 hypothetical protein 2773197 7773844 VCM66_2587 Vibrio cholerae M66-2 hypothetical protein YP_002811334.1 2772838 D 579112 CDS YP_002811335.1 227082784 7773845 complement(2773324..2773764) 1 NC_012578.1 hypothetical protein 2773764 7773845 VCM66_2588 Vibrio cholerae M66-2 hypothetical protein YP_002811335.1 2773324 R 579112 CDS YP_002811336.1 227082785 7773846 complement(2773784..2774134) 1 NC_012578.1 putative 5-carboxymethyl-2-hydroxymuconate delta isomerase 2774134 7773846 VCM66_2589 Vibrio cholerae M66-2 putative 5-carboxymethyl-2-hydroxymuconate delta isomerase YP_002811336.1 2773784 R 579112 CDS YP_002811337.1 227082786 7773847 2774354..2775151 1 NC_012578.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2775151 tpiA 7773847 tpiA Vibrio cholerae M66-2 triosephosphate isomerase YP_002811337.1 2774354 D 579112 CDS YP_002811338.1 227082787 7773848 2775269..2776651 1 NC_012578.1 hypothetical protein 2776651 7773848 VCM66_2591 Vibrio cholerae M66-2 hypothetical protein YP_002811338.1 2775269 D 579112 CDS YP_002811339.1 227082788 7773849 complement(2776738..2777253) 1 NC_012578.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 2777253 menG-2 7773849 menG-2 Vibrio cholerae M66-2 ribonuclease activity regulator protein RraA YP_002811339.1 2776738 R 579112 CDS YP_002811340.1 227082789 7773850 complement(2777328..2778245) 1 NC_012578.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 2778245 menA 7773850 menA Vibrio cholerae M66-2 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002811340.1 2777328 R 579112 CDS YP_002811341.1 227082790 7773851 complement(2778349..2779680) 1 NC_012578.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 2779680 hslU 7773851 hslU Vibrio cholerae M66-2 ATP-dependent protease ATP-binding subunit HslU YP_002811341.1 2778349 R 579112 CDS YP_002811342.1 227082791 7773852 complement(2779746..2780303) 1 NC_012578.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 2780303 hslV 7773852 hslV Vibrio cholerae M66-2 ATP-dependent protease peptidase subunit YP_002811342.1 2779746 R 579112 CDS YP_002811343.1 227082792 7773853 complement(2780440..2780991) 1 NC_012578.1 putative cell division protein FtsN 2780991 7773853 VCM66_2596 Vibrio cholerae M66-2 putative cell division protein FtsN YP_002811343.1 2780440 R 579112 CDS YP_002811344.1 227082793 7773854 complement(2781163..2782170) 1 NC_012578.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 2782170 7773854 VCM66_2597 Vibrio cholerae M66-2 DNA-binding transcriptional regulator CytR YP_002811344.1 2781163 R 579112 CDS YP_002811345.1 227082794 7773855 complement(2782476..2784680) 1 NC_012578.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2784680 priA 7773855 priA Vibrio cholerae M66-2 primosome assembly protein PriA YP_002811345.1 2782476 R 579112 CDS YP_002811346.1 227082795 7773856 2784935..2785153 1 NC_012578.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2785153 rpmE 7773856 rpmE Vibrio cholerae M66-2 50S ribosomal protein L31 YP_002811346.1 2784935 D 579112 CDS YP_002811347.1 227082796 7773857 2785251..2785394 1 NC_012578.1 hypothetical protein 2785394 7773857 VCM66_2600 Vibrio cholerae M66-2 hypothetical protein YP_002811347.1 2785251 D 579112 CDS YP_002811348.1 227082797 7773858 2785461..2786738 1 NC_012578.1 putative malate oxidoreductase 2786738 7773858 VCM66_2601 Vibrio cholerae M66-2 putative malate oxidoreductase YP_002811348.1 2785461 D 579112 CDS YP_002811349.1 227082798 7773859 complement(2786849..2787166) 1 NC_012578.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 2787166 metJ 7773859 metJ Vibrio cholerae M66-2 transcriptional repressor protein MetJ YP_002811349.1 2786849 R 579112 CDS YP_002811350.1 227082799 7773860 2787434..2788600 1 NC_012578.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 2788600 metB 7773860 metB Vibrio cholerae M66-2 cystathionine gamma-synthase YP_002811350.1 2787434 D 579112 CDS YP_002811351.1 227082800 7773861 2788613..2791024 1 NC_012578.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 2791024 metL 7773861 metL Vibrio cholerae M66-2 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002811351.1 2788613 D 579112 CDS YP_002811352.1 227082801 7773862 2791284..2792198 1 NC_012578.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 2792198 metF 7773862 metF Vibrio cholerae M66-2 5,10-methylenetetrahydrofolate reductase YP_002811352.1 2791284 D 579112 CDS YP_002811353.1 227082802 7773863 complement(2792261..2792503) 1 NC_012578.1 hypothetical protein 2792503 7773863 VCM66_2606 Vibrio cholerae M66-2 hypothetical protein YP_002811353.1 2792261 R 579112 CDS YP_002811354.1 227082803 7773864 2792552..2792656 1 NC_012578.1 hypothetical protein 2792656 7773864 VCM66_2607 Vibrio cholerae M66-2 hypothetical protein YP_002811354.1 2792552 D 579112 CDS YP_002811355.1 227082804 7773865 2792824..2793831 1 NC_012578.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 2793831 glpX 7773865 glpX Vibrio cholerae M66-2 fructose 1,6-bisphosphatase II YP_002811355.1 2792824 D 579112 CDS YP_002811356.1 227082805 7773866 complement(2793908..2794903) 1 NC_012578.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 2794903 pfkA 7773866 pfkA Vibrio cholerae M66-2 6-phosphofructokinase YP_002811356.1 2793908 R 579112 CDS YP_002811357.1 227082806 7773867 complement(2795133..2796041) 1 NC_012578.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 2796041 fieF 7773867 fieF Vibrio cholerae M66-2 ferrous iron efflux protein F YP_002811357.1 2795133 R 579112 CDS YP_002811358.1 227082807 7773868 complement(2796239..2796742) 1 NC_012578.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 2796742 cpxP 7773868 cpxP Vibrio cholerae M66-2 periplasmic repressor CpxP YP_002811358.1 2796239 R 579112 CDS YP_002811359.1 227082808 7773869 2796930..2797616 1 NC_012578.1 transcriptional regulator CpxR 2797616 cpxR 7773869 cpxR Vibrio cholerae M66-2 transcriptional regulator CpxR YP_002811359.1 2796930 D 579112 CDS YP_002811360.1 227082809 7773870 2797616..2799010 1 NC_012578.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 2799010 cpxA 7773870 cpxA Vibrio cholerae M66-2 two-component sensor protein YP_002811360.1 2797616 D 579112 CDS YP_002811361.1 227082810 7773871 2799092..2799760 1 NC_012578.1 superoxide dismutase, Mn 2799760 sodA 7773871 sodA Vibrio cholerae M66-2 superoxide dismutase, Mn YP_002811361.1 2799092 D 579112 CDS YP_002811362.1 227082811 7773872 2799813..2800289 1 NC_012578.1 rRNA methylase, SpoU family 2800289 7773872 VCM66_2615 Vibrio cholerae M66-2 rRNA methylase, SpoU family YP_002811362.1 2799813 D 579112 CDS YP_002811363.1 227082812 7773873 complement(2800323..2800808) 1 NC_012578.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 2800808 fxsA 7773873 fxsA Vibrio cholerae M66-2 FxsA YP_002811363.1 2800323 R 579112 CDS YP_002811364.1 227082813 7773874 complement(2800900..2801838) 1 NC_012578.1 GGDEF family protein 2801838 7773874 VCM66_2617 Vibrio cholerae M66-2 GGDEF family protein YP_002811364.1 2800900 R 579112 CDS YP_002811365.1 227082814 7773875 2802083..2803534 1 NC_012578.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 2803534 aspA 7773875 aspA Vibrio cholerae M66-2 aspartate ammonia-lyase YP_002811365.1 2802083 D 579112 CDS YP_002811366.1 227082815 7773876 2803614..2804969 1 NC_012578.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 2804969 dcuA 7773876 dcuA Vibrio cholerae M66-2 anaerobic C4-dicarboxylate transporter YP_002811366.1 2803614 D 579112 CDS YP_002811367.1 227082816 7773967 2809121..2810923 1 NC_012578.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 2810923 dipZ 7773967 dipZ Vibrio cholerae M66-2 thiol:disulfide interchange protein YP_002811367.1 2809121 D 579112 CDS YP_002811368.1 227082817 7773878 2811096..2811725 1 NC_012578.1 LuxR family transcriptional reguator 2811725 7773878 VCM66_2622 Vibrio cholerae M66-2 LuxR family transcriptional reguator YP_002811368.1 2811096 D 579112 CDS YP_002811369.1 227082818 7773879 complement(2811824..2813569) 1 NC_012578.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 2813569 7773879 VCM66_2623 Vibrio cholerae M66-2 potassium/proton antiporter YP_002811369.1 2811824 R 579112 CDS YP_002811370.1 227082819 7773880 2813948..2814214 1 NC_012578.1 hypothetical protein 2814214 7773880 VCM66_2624 Vibrio cholerae M66-2 hypothetical protein YP_002811370.1 2813948 D 579112 CDS YP_002811371.1 227082820 7773881 2814408..2815928 1 NC_012578.1 putative sodium/solute symporter 2815928 7773881 VCM66_2625 Vibrio cholerae M66-2 putative sodium/solute symporter YP_002811371.1 2814408 D 579112 CDS YP_002811372.1 227082821 7773882 complement(2816026..2816697) 1 NC_012578.1 hypothetical protein 2816697 7773882 VCM66_2626 Vibrio cholerae M66-2 hypothetical protein YP_002811372.1 2816026 R 579112 CDS YP_002811373.1 227082822 7773883 2816999..2817688 1 NC_012578.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2817688 gmk 7773883 gmk Vibrio cholerae M66-2 guanylate kinase YP_002811373.1 2816999 D 579112 CDS YP_002811374.1 227082823 7773884 2817796..2818068 1 NC_012578.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2818068 rpoZ 7773884 rpoZ Vibrio cholerae M66-2 DNA-directed RNA polymerase subunit omega YP_002811374.1 2817796 D 579112 CDS YP_002811375.1 227082824 7773885 2818100..2820217 1 NC_012578.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 2820217 spoT 7773885 spoT Vibrio cholerae M66-2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002811375.1 2818100 D 579112 CDS YP_002811376.1 227082825 7773886 2820336..2822414 1 NC_012578.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2822414 recG 7773886 recG Vibrio cholerae M66-2 ATP-dependent DNA helicase RecG YP_002811376.1 2820336 D 579112 CDS YP_002811377.1 227082826 7773887 2822723..2824165 1 NC_012578.1 xanthine/uracil permease family protein 2824165 7773887 VCM66_2632 Vibrio cholerae M66-2 xanthine/uracil permease family protein YP_002811377.1 2822723 D 579112 CDS YP_002811378.1 227082827 7773888 complement(2824190..2825506) 1 NC_012578.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 2825506 envZ 7773888 envZ Vibrio cholerae M66-2 osmolarity sensor protein YP_002811378.1 2824190 R 579112 CDS YP_002811379.1 227082828 7773889 complement(2825575..2826297) 1 NC_012578.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 2826297 ompR 7773889 ompR Vibrio cholerae M66-2 osmolarity response regulator YP_002811379.1 2825575 R 579112 CDS YP_002811380.1 227082829 7773890 complement(2826435..2826920) 1 NC_012578.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 2826920 greB 7773890 greB Vibrio cholerae M66-2 transcription elongation factor GreB YP_002811380.1 2826435 R 579112 CDS YP_002811381.1 227082830 7773891 2827165..2829486 1 NC_012578.1 hypothetical protein 2829486 7773891 VCM66_2636 Vibrio cholerae M66-2 hypothetical protein YP_002811381.1 2827165 D 579112 CDS YP_002811382.1 227082831 7773892 complement(2829578..2830075) 1 NC_012578.1 hypothetical protein 2830075 7773892 VCM66_2637 Vibrio cholerae M66-2 hypothetical protein YP_002811382.1 2829578 R 579112 CDS YP_002811383.1 227082832 7773893 complement(2830210..2831016) 1 NC_012578.1 bioH protein 2831016 bioH 7773893 bioH Vibrio cholerae M66-2 bioH protein YP_002811383.1 2830210 R 579112 CDS YP_002811384.1 227082833 7773894 2830907..2831767 1 NC_012578.1 ComF-like protein 2831767 7773894 VCM66_2639 Vibrio cholerae M66-2 ComF-like protein YP_002811384.1 2830907 D 579112 CDS YP_002811385.1 227082834 7773895 2831855..2832442 1 NC_012578.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 2832442 7773895 VCM66_2640 Vibrio cholerae M66-2 putative DNA uptake protein YP_002811385.1 2831855 D 579112 CDS YP_002811386.1 227082835 7773896 2832515..2833129 1 NC_012578.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 2833129 nudE 7773896 nudE Vibrio cholerae M66-2 ADP-ribose diphosphatase NudE YP_002811386.1 2832515 D 579112 CDS YP_002811387.1 227082836 7773897 2833074..2833979 1 NC_012578.1 cysQ protein 2833979 cysQ 7773897 cysQ Vibrio cholerae M66-2 cysQ protein YP_002811387.1 2833074 D 579112 CDS YP_002811388.1 227082837 7773898 complement(2834031..2834789) 1 NC_012578.1 general secretion pathway protein N 2834789 epsN 7773898 epsN Vibrio cholerae M66-2 general secretion pathway protein N YP_002811388.1 2834031 R 579112 CDS YP_002811389.1 227082838 7773899 complement(2834791..2835291) 1 NC_012578.1 cholera toxin secretion protein EpsM 2835291 epsM 7773899 epsM Vibrio cholerae M66-2 cholera toxin secretion protein EpsM YP_002811389.1 2834791 R 579112 CDS YP_002811390.1 227082839 7773900 complement(2835298..2836521) 1 NC_012578.1 general secretion pathway protein L 2836521 epsL 7773900 epsL Vibrio cholerae M66-2 general secretion pathway protein L YP_002811390.1 2835298 R 579112 CDS YP_002811391.1 227082840 7773901 complement(2836478..2837488) 1 NC_012578.1 general secretion pathway protein K 2837488 epsK 7773901 epsK Vibrio cholerae M66-2 general secretion pathway protein K YP_002811391.1 2836478 R 579112 CDS YP_002811392.1 227082841 7773902 complement(2837478..2838143) 1 NC_012578.1 general secretion pathway protein J 2838143 epsJ 7773902 epsJ Vibrio cholerae M66-2 general secretion pathway protein J YP_002811392.1 2837478 R 579112 CDS YP_002811393.1 227082842 7773903 complement(2838130..2838483) 1 NC_012578.1 general secretion pathway protein I 2838483 epsI 7773903 epsI Vibrio cholerae M66-2 general secretion pathway protein I YP_002811393.1 2838130 R 579112 CDS YP_002811394.1 227082843 7773904 complement(2838473..2839057) 1 NC_012578.1 general secretion pathway protein H 2839057 epsH 7773904 epsH Vibrio cholerae M66-2 general secretion pathway protein H YP_002811394.1 2838473 R 579112 CDS YP_002811395.1 227082844 7773905 complement(2839091..2839531) 1 NC_012578.1 general secretion pathway protein G 2839531 epsG 7773905 epsG Vibrio cholerae M66-2 general secretion pathway protein G YP_002811395.1 2839091 R 579112 CDS YP_002811396.1 227082845 7773906 complement(2839572..2840792) 1 NC_012578.1 general secretion pathway protein F 2840792 epsF 7773906 epsF Vibrio cholerae M66-2 general secretion pathway protein F YP_002811396.1 2839572 R 579112 CDS YP_002811397.1 227082846 7773907 complement(2840792..2842303) 1 NC_012578.1 general secretion pathway protein E 2842303 epsE 7773907 epsE Vibrio cholerae M66-2 general secretion pathway protein E YP_002811397.1 2840792 R 579112 CDS YP_002811398.1 227082847 7773908 complement(2842300..2844324) 1 NC_012578.1 general secretion pathway protein D 2844324 gspD 7773908 gspD Vibrio cholerae M66-2 general secretion pathway protein D YP_002811398.1 2842300 R 579112 CDS YP_002811399.1 227082848 7773909 complement(2844370..2845287) 1 NC_012578.1 general secretion pathway protein C 2845287 epsC 7773909 epsC Vibrio cholerae M66-2 general secretion pathway protein C YP_002811399.1 2844370 R 579112 CDS YP_002811400.1 227082849 7773910 2845511..2845894 1 NC_012578.1 Heat shock protein 15 2845894 7773910 VCM66_2655 Vibrio cholerae M66-2 Heat shock protein 15 YP_002811400.1 2845511 D 579112 CDS YP_002811401.1 227082850 7773911 2845913..2846803 1 NC_012578.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2846803 hslO 7773911 hslO Vibrio cholerae M66-2 Hsp33-like chaperonin YP_002811401.1 2845913 D 579112 CDS YP_002811402.1 227082851 7773912 complement(2846942..2847091) 1 NC_012578.1 hypothetical protein 2847091 7773912 VCM66_2657 Vibrio cholerae M66-2 hypothetical protein YP_002811402.1 2846942 R 579112 CDS YP_002811403.1 227082852 7773913 2847140..2848768 1 NC_012578.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 2848768 pckA 7773913 pckA Vibrio cholerae M66-2 phosphoenolpyruvate carboxykinase YP_002811403.1 2847140 D 579112 CDS YP_002811404.1 227082853 7773914 2848955..2850841 1 NC_012578.1 hypothetical protein 2850841 7773914 VCM66_2659 Vibrio cholerae M66-2 hypothetical protein YP_002811404.1 2848955 D 579112 CDS YP_002811405.1 227082854 7773915 complement(2850883..2851815) 1 NC_012578.1 hypothetical protein 2851815 7773915 VCM66_2660 Vibrio cholerae M66-2 hypothetical protein YP_002811405.1 2850883 R 579112 CDS YP_002811406.1 227082855 7773916 complement(2851882..2852316) 1 NC_012578.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2852316 7773916 VCM66_2661 Vibrio cholerae M66-2 D-tyrosyl-tRNA(Tyr) deacylase YP_002811406.1 2851882 R 579112 CDS YP_002811407.1 227082856 7773917 complement(2852334..2853227) 1 NC_012578.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 2853227 rbn 7773917 rbn Vibrio cholerae M66-2 ribonuclease BN YP_002811407.1 2852334 R 579112 CDS YP_002811408.1 227082857 7773918 complement(2853254..2853808) 1 NC_012578.1 hypothetical protein 2853808 7773918 VCM66_2663 Vibrio cholerae M66-2 hypothetical protein YP_002811408.1 2853254 R 579112 CDS YP_002811409.1 227082858 7773919 complement(2853891..2855720) 1 NC_012578.1 GTP-binding protein TypA 2855720 typA 7773919 typA Vibrio cholerae M66-2 GTP-binding protein TypA YP_002811409.1 2853891 R 579112 CDS YP_002811410.1 227082859 7773920 complement(2855740..2856063) 1 NC_012578.1 hypothetical protein 2856063 7773920 VCM66_2665 Vibrio cholerae M66-2 hypothetical protein YP_002811410.1 2855740 R 579112 CDS YP_002811411.1 227082860 7773921 2856208..2857617 1 NC_012578.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 2857617 glnA 7773921 glnA Vibrio cholerae M66-2 glutamine synthetase YP_002811411.1 2856208 D 579112 CDS YP_002811412.1 227082861 7773922 2857795..2858385 1 NC_012578.1 hypothetical protein 2858385 7773922 VCM66_2667 Vibrio cholerae M66-2 hypothetical protein YP_002811412.1 2857795 D 579112 CDS YP_002811413.1 227082862 7773923 2858518..2859582 1 NC_012578.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 2859582 glnL 7773923 glnL Vibrio cholerae M66-2 nitrogen regulation protein NR(II) YP_002811413.1 2858518 D 579112 CDS YP_002811414.1 227082863 7773924 2859586..2860992 1 NC_012578.1 nitrogen regulation protein NR(I) 2860992 ntrC 7773924 ntrC Vibrio cholerae M66-2 nitrogen regulation protein NR(I) YP_002811414.1 2859586 D 579112 CDS YP_002811415.1 227082864 7773925 2861033..2863582 1 NC_012578.1 GGDEF/EAL family protein 2863582 7773925 VCM66_2670 Vibrio cholerae M66-2 GGDEF/EAL family protein YP_002811415.1 2861033 D 579112 CDS YP_002811416.1 227082865 7773926 2863674..2864678 1 NC_012578.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 2864678 add 7773926 add Vibrio cholerae M66-2 adenosine deaminase YP_002811416.1 2863674 D 579112 CDS YP_002811417.1 227082866 7773974 complement(2870710..2870856) 1 NC_012578.1 hypothetical protein 2870856 7773974 VCM66_2674 Vibrio cholerae M66-2 hypothetical protein YP_002811417.1 2870710 R 579112 CDS YP_002811418.1 227082867 7773928 complement(2870831..2871355) 1 NC_012578.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 2871355 hemG 7773928 hemG Vibrio cholerae M66-2 protoporphyrinogen oxidase YP_002811418.1 2870831 R 579112 CDS YP_002811419.1 227082868 7773929 complement(2871378..2872835) 1 NC_012578.1 potassium uptake protein TrkH 2872835 trkH-2 7773929 trkH-2 Vibrio cholerae M66-2 potassium uptake protein TrkH YP_002811419.1 2871378 R 579112 CDS YP_002811420.1 227082869 7773930 complement(2872855..2873487) 1 NC_012578.1 hypothetical protein 2873487 7773930 VCM66_2677 Vibrio cholerae M66-2 hypothetical protein YP_002811420.1 2872855 R 579112 CDS YP_002811421.1 227082870 7773931 2873698..2875869 1 NC_012578.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 2875869 fadB 7773931 fadB Vibrio cholerae M66-2 multifunctional fatty acid oxidation complex subunit alpha YP_002811421.1 2873698 D 579112 CDS YP_002811422.1 227082871 7773932 2875895..2877058 1 NC_012578.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 2877058 fadA 7773932 fadA Vibrio cholerae M66-2 3-ketoacyl-CoA thiolase YP_002811422.1 2875895 D 579112 CDS YP_002811423.1 227082872 7773933 complement(2877125..2878033) 1 NC_012578.1 putative DNA-binding transcriptional regulator 2878033 7773933 VCM66_2680 Vibrio cholerae M66-2 putative DNA-binding transcriptional regulator YP_002811423.1 2877125 R 579112 CDS YP_002811424.1 227082873 7773934 2878162..2879391 1 NC_012578.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2879391 7773934 VCM66_2681 Vibrio cholerae M66-2 inner membrane transport protein YdhC YP_002811424.1 2878162 D 579112 CDS YP_002811425.1 227082874 7773935 complement(2879451..2880812) 1 NC_012578.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 2880812 glmU 7773935 glmU Vibrio cholerae M66-2 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002811425.1 2879451 R 579112 CDS YP_002811426.1 227082875 7773936 complement(2881059..2881481) 1 NC_012578.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 2881481 atpC 7773936 atpC Vibrio cholerae M66-2 F0F1 ATP synthase subunit epsilon YP_002811426.1 2881059 R 579112 CDS YP_002811427.1 227082876 7773937 complement(2881500..2882903) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 2882903 atpD 7773937 atpD Vibrio cholerae M66-2 F0F1 ATP synthase subunit beta YP_002811427.1 2881500 R 579112 CDS YP_002811428.1 227082877 7773938 complement(2882938..2883804) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 2883804 atpG 7773938 atpG Vibrio cholerae M66-2 F0F1 ATP synthase subunit gamma YP_002811428.1 2882938 R 579112 CDS YP_002811429.1 227082878 7773939 complement(2883849..2885420) 1 NC_012578.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 2885420 atpA 7773939 atpA Vibrio cholerae M66-2 F0F1 ATP synthase subunit alpha YP_002811429.1 2883849 R 579112 CDS YP_002811430.1 227082879 7773940 complement(2885404..2885937) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 2885937 atpH 7773940 atpH Vibrio cholerae M66-2 F0F1 ATP synthase subunit delta YP_002811430.1 2885404 R 579112 CDS YP_002811431.1 227082880 7773941 complement(2885952..2886422) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 2886422 atpF 7773941 atpF Vibrio cholerae M66-2 F0F1 ATP synthase subunit B YP_002811431.1 2885952 R 579112 CDS YP_002811432.1 227082881 7773942 complement(2886496..2886753) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 2886753 atpE 7773942 atpE Vibrio cholerae M66-2 F0F1 ATP synthase subunit C YP_002811432.1 2886496 R 579112 CDS YP_002811433.1 227082882 7773943 complement(2886797..2887609) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 2887609 atpB 7773943 atpB Vibrio cholerae M66-2 F0F1 ATP synthase subunit A YP_002811433.1 2886797 R 579112 CDS YP_002811434.1 227082883 7773944 complement(2887618..2888007) 1 NC_012578.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 2888007 atpI 7773944 atpI Vibrio cholerae M66-2 F0F1 ATP synthase subunit I YP_002811434.1 2887618 R 579112 CDS YP_002811435.1 227082884 7773945 complement(2888197..2889078) 1 NC_012578.1 ParB family protein 2889078 7773945 VCM66_2692 Vibrio cholerae M66-2 ParB family protein YP_002811435.1 2888197 R 579112 CDS YP_002811436.1 227082885 7773946 complement(2889105..2889878) 1 NC_012578.1 ParA family protein 2889878 7773946 VCM66_2693 Vibrio cholerae M66-2 ParA family protein YP_002811436.1 2889105 R 579112 CDS YP_002811437.1 227082886 7773947 complement(2889893..2890525) 1 NC_012578.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2890525 gidB 7773947 gidB Vibrio cholerae M66-2 16S rRNA methyltransferase GidB YP_002811437.1 2889893 R 579112 CDS YP_002811438.1 227082887 7773948 complement(2890525..2892420) 1 NC_012578.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2892420 gidA 7773948 gidA Vibrio cholerae M66-2 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002811438.1 2890525 R 579112 CDS YP_002811645.1 227811635 7781299 complement(112..246) 1 NC_012580.1 hypothetical protein 246 7781299 VCM66_A0001 Vibrio cholerae M66-2 hypothetical protein YP_002811645.1 112 R 579112 CDS YP_002811646.1 227811636 7781300 1134..3110 1 NC_012580.1 hypothetical protein 3110 7781300 VCM66_A0002 Vibrio cholerae M66-2 hypothetical protein YP_002811646.1 1134 D 579112 CDS YP_002811647.1 227811637 7781301 complement(3330..3944) 1 NC_012580.1 hypothetical protein 3944 7781301 VCM66_A0003 Vibrio cholerae M66-2 hypothetical protein YP_002811647.1 3330 R 579112 CDS YP_002811648.1 227811638 7781302 4154..4351 1 NC_012580.1 hypothetical protein 4351 7781302 VCM66_A0004 Vibrio cholerae M66-2 hypothetical protein YP_002811648.1 4154 D 579112 CDS YP_002811649.1 227811639 7781303 4445..4723 1 NC_012580.1 hypothetical protein 4723 7781303 VCM66_A0005 Vibrio cholerae M66-2 hypothetical protein YP_002811649.1 4445 D 579112 CDS YP_002811650.1 227811640 7781304 4811..5530 1 NC_012580.1 hypothetical protein 5530 7781304 VCM66_A0006 Vibrio cholerae M66-2 hypothetical protein YP_002811650.1 4811 D 579112 CDS YP_002811651.1 227811641 7781305 5573..6520 1 NC_012580.1 putative 3-hydroxyisobutyrate dehydrogenase 6520 7781305 VCM66_A0007 Vibrio cholerae M66-2 putative 3-hydroxyisobutyrate dehydrogenase YP_002811651.1 5573 D 579112 CDS YP_002811652.1 227811642 7781306 complement(6624..8285) 1 NC_012580.1 methyl-accepting chemotaxis protein 8285 7781306 VCM66_A0008 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811652.1 6624 R 579112 CDS YP_002811653.1 227811643 7781307 8484..8921 1 NC_012580.1 hypothetical protein 8921 7781307 VCM66_A0010 Vibrio cholerae M66-2 hypothetical protein YP_002811653.1 8484 D 579112 CDS YP_002811654.1 227811644 7781308 complement(8987..11737) 1 NC_012580.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 11737 malT 7781308 malT Vibrio cholerae M66-2 transcriptional regulator MalT YP_002811654.1 8987 R 579112 CDS YP_002811655.1 227811645 7781309 12257..14710 1 NC_012580.1 maltodextrin phosphorylase 14710 malP 7781309 malP Vibrio cholerae M66-2 maltodextrin phosphorylase YP_002811655.1 12257 D 579112 CDS YP_002811656.1 227811646 7781310 14796..16976 1 NC_012580.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 16976 malQ 7781310 malQ Vibrio cholerae M66-2 4-alpha-glucanotransferase YP_002811656.1 14796 D 579112 CDS YP_002811657.1 227811647 7781311 17230..19371 1 NC_012580.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 19371 glgB 7781311 glgB Vibrio cholerae M66-2 glycogen branching enzyme YP_002811657.1 17230 D 579112 CDS YP_002811658.1 227811648 7781312 19766..20284 1 NC_012580.1 hcp protein 20284 hcp-2 7781312 hcp-2 Vibrio cholerae M66-2 hcp protein YP_002811658.1 19766 D 579112 CDS YP_002811659.1 227811649 7781313 20412..22496 1 NC_012580.1 vgrG protein 22496 vgrG-2 7781313 vgrG-2 Vibrio cholerae M66-2 vgrG protein YP_002811659.1 20412 D 579112 CDS YP_002811660.1 227811650 7781314 22496..23383 1 NC_012580.1 hypothetical protein 23383 7781314 VCM66_A0018 Vibrio cholerae M66-2 hypothetical protein YP_002811660.1 22496 D 579112 CDS YP_002811661.1 227811651 7781315 23380..26646 1 NC_012580.1 hypothetical protein 26646 7781315 VCM66_A0019 Vibrio cholerae M66-2 hypothetical protein YP_002811661.1 23380 D 579112 CDS YP_002811662.1 227811652 7781316 26647..27375 1 NC_012580.1 hypothetical protein 27375 7781316 VCM66_A0020 Vibrio cholerae M66-2 hypothetical protein YP_002811662.1 26647 D 579112 CDS YP_002811663.1 227811653 7781317 27478..27879 1 NC_012580.1 glutathione S-transfersae-related protein 27879 7781317 VCM66_A0021 Vibrio cholerae M66-2 glutathione S-transfersae-related protein YP_002811663.1 27478 D 579112 CDS YP_002811664.1 227811654 7781318 complement(28052..29092) 1 NC_012580.1 hypothetical protein 29092 7781318 VCM66_A0022 Vibrio cholerae M66-2 hypothetical protein YP_002811664.1 28052 R 579112 CDS YP_002811665.1 227811655 7781319 complement(29208..30200) 1 NC_012580.1 hypothetical protein 30200 7781319 VCM66_A0023 Vibrio cholerae M66-2 hypothetical protein YP_002811665.1 29208 R 579112 CDS YP_002811666.1 227811656 7781320 30478..31866 1 NC_012580.1 transporter, NadC family 31866 7781320 VCM66_A0024 Vibrio cholerae M66-2 transporter, NadC family YP_002811666.1 30478 D 579112 CDS YP_002811667.1 227811657 7781321 complement(31962..32597) 1 NC_012580.1 hypothetical protein 32597 7781321 VCM66_A0025 Vibrio cholerae M66-2 hypothetical protein YP_002811667.1 31962 R 579112 CDS YP_002811668.1 227811658 7781322 33029..35575 1 NC_012580.1 chitinase 35575 chiA-2 7781322 chiA-2 Vibrio cholerae M66-2 chitinase YP_002811668.1 33029 D 579112 CDS YP_002811669.1 227811659 7781323 35941..36675 1 NC_012580.1 putative transcriptional regulator 36675 7781323 VCM66_A0028 Vibrio cholerae M66-2 putative transcriptional regulator YP_002811669.1 35941 D 579112 CDS YP_002811670.1 227811660 7781324 36676..37518 1 NC_012580.1 hypothetical protein 37518 7781324 VCM66_A0029 Vibrio cholerae M66-2 hypothetical protein YP_002811670.1 36676 D 579112 CDS YP_002811671.1 227811661 7781325 complement(37639..39204) 1 NC_012580.1 methyl-accepting chemotaxis protein 39204 7781325 VCM66_A0030 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811671.1 37639 R 579112 CDS YP_002811672.1 227811662 7781326 complement(39302..39862) 1 NC_012580.1 hypothetical protein 39862 7781326 VCM66_A0031 Vibrio cholerae M66-2 hypothetical protein YP_002811672.1 39302 R 579112 CDS YP_002811673.1 227811663 7781327 40271..42145 1 NC_012580.1 hypothetical protein 42145 7781327 VCM66_A0032 Vibrio cholerae M66-2 hypothetical protein YP_002811673.1 40271 D 579112 CDS YP_002811674.1 227811664 7781328 complement(42205..43077) 1 NC_012580.1 hypothetical protein 43077 7781328 VCM66_A0033 Vibrio cholerae M66-2 hypothetical protein YP_002811674.1 42205 R 579112 CDS YP_002811675.1 227811665 7781329 43193..44017 1 NC_012580.1 putative phosphatidylglycerophosphatase B 44017 7781329 VCM66_A0034 Vibrio cholerae M66-2 putative phosphatidylglycerophosphatase B YP_002811675.1 43193 D 579112 CDS YP_002811676.1 227811666 7781330 complement(44071..45288) 1 NC_012580.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 45288 7781330 VCM66_A0035 Vibrio cholerae M66-2 serine/threonine transporter SstT YP_002811676.1 44071 R 579112 CDS YP_002811677.1 227811667 7781331 complement(45630..46082) 1 NC_012580.1 hypothetical protein 46082 7781331 VCM66_A0036 Vibrio cholerae M66-2 hypothetical protein YP_002811677.1 45630 R 579112 CDS YP_002811678.1 227811668 7781332 complement(46096..46677) 1 NC_012580.1 Sco1-related protein 46677 7781332 VCM66_A0037 Vibrio cholerae M66-2 Sco1-related protein YP_002811678.1 46096 R 579112 CDS YP_002811679.1 227811669 7781333 complement(46674..47096) 1 NC_012580.1 hypothetical protein 47096 7781333 VCM66_A0038 Vibrio cholerae M66-2 hypothetical protein YP_002811679.1 46674 R 579112 CDS YP_002811680.1 227811670 7781334 complement(47295..48221) 1 NC_012580.1 hypothetical protein 48221 7781334 VCM66_A0039 Vibrio cholerae M66-2 hypothetical protein YP_002811680.1 47295 R 579112 CDS YP_002811681.1 227811671 7781335 48760..49986 1 NC_012580.1 sodium/glutamate symporter 49986 glts 7781335 glts Vibrio cholerae M66-2 sodium/glutamate symporter YP_002811681.1 48760 D 579112 CDS YP_002811682.1 227811672 7781336 complement(50065..50823) 1 NC_012580.1 hypothetical protein 50823 7781336 VCM66_A0041 Vibrio cholerae M66-2 hypothetical protein YP_002811682.1 50065 R 579112 CDS YP_002811683.1 227811673 7781337 50955..51239 1 NC_012580.1 hypothetical protein 51239 7781337 VCM66_A0042 Vibrio cholerae M66-2 hypothetical protein YP_002811683.1 50955 D 579112 CDS YP_002811684.1 227811674 7781338 51472..54726 1 NC_012580.1 putative tricorn protease 54726 7781338 VCM66_A0043 Vibrio cholerae M66-2 putative tricorn protease YP_002811684.1 51472 D 579112 CDS YP_002811685.1 227811675 7781339 complement(54718..54840) 1 NC_012580.1 hypothetical protein 54840 7781339 VCM66_A0044 Vibrio cholerae M66-2 hypothetical protein YP_002811685.1 54718 R 579112 CDS YP_002811686.1 227811676 7781340 complement(54921..56051) 1 NC_012580.1 hypothetical protein 56051 7781340 VCM66_A0045 Vibrio cholerae M66-2 hypothetical protein YP_002811686.1 54921 R 579112 CDS YP_002811687.1 227811677 7781341 complement(56051..56440) 1 NC_012580.1 hypothetical protein 56440 7781341 VCM66_A0046 Vibrio cholerae M66-2 hypothetical protein YP_002811687.1 56051 R 579112 CDS YP_002811688.1 227811678 7781342 complement(56575..58182) 1 NC_012580.1 GGDEF family protein 58182 7781342 VCM66_A0047 Vibrio cholerae M66-2 GGDEF family protein YP_002811688.1 56575 R 579112 CDS YP_002811689.1 227811679 7781343 complement(58136..59659) 1 NC_012580.1 hypothetical protein 59659 7781343 VCM66_A0048 Vibrio cholerae M66-2 hypothetical protein YP_002811689.1 58136 R 579112 CDS YP_002811690.1 227811680 7781344 complement(59778..61340) 1 NC_012580.1 hypothetical protein 61340 7781344 VCM66_A0049 Vibrio cholerae M66-2 hypothetical protein YP_002811690.1 59778 R 579112 CDS YP_002811691.1 227811681 7781345 complement(61312..62049) 1 NC_012580.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 62049 deoD-2 7781345 deoD-2 Vibrio cholerae M66-2 purine nucleoside phosphorylase YP_002811691.1 61312 R 579112 CDS YP_002811692.1 227811682 7781346 complement(62108..62287) 1 NC_012580.1 hypothetical protein 62287 7781346 VCM66_A0051 Vibrio cholerae M66-2 hypothetical protein YP_002811692.1 62108 R 579112 CDS YP_002811693.1 227811683 7781347 62329..63297 1 NC_012580.1 hypothetical protein 63297 7781347 VCM66_A0052 Vibrio cholerae M66-2 hypothetical protein YP_002811693.1 62329 D 579112 CDS YP_002811694.1 227811684 7781348 63287..64084 1 NC_012580.1 transcriptional regulator, MerR family 64084 7781348 VCM66_A0053 Vibrio cholerae M66-2 transcriptional regulator, MerR family YP_002811694.1 63287 D 579112 CDS YP_002811695.1 227811685 7781349 64094..65503 1 NC_012580.1 deoxyribodipyrimidine photolyase 65503 phrB-2 7781349 phrB-2 Vibrio cholerae M66-2 deoxyribodipyrimidine photolyase YP_002811695.1 64094 D 579112 CDS YP_002811696.1 227811686 7781350 65512..66432 1 NC_012580.1 hypothetical protein 66432 7781350 VCM66_A0055 Vibrio cholerae M66-2 hypothetical protein YP_002811696.1 65512 D 579112 CDS YP_002811697.1 227811687 7781351 complement(66518..66877) 1 NC_012580.1 major outer membrane lipoprotein 66877 lpp 7781351 lpp Vibrio cholerae M66-2 major outer membrane lipoprotein YP_002811697.1 66518 R 579112 CDS YP_002811698.1 227811688 7781352 67296..68654 1 NC_012580.1 ATP-dependent RNA helicase, DEAD box family 68654 7781352 VCM66_A0058 Vibrio cholerae M66-2 ATP-dependent RNA helicase, DEAD box family YP_002811698.1 67296 D 579112 CDS YP_002811699.1 227811689 7781353 complement(68651..68761) 1 NC_012580.1 hypothetical protein 68761 7781353 VCM66_A0059 Vibrio cholerae M66-2 hypothetical protein YP_002811699.1 68651 R 579112 CDS YP_002811700.1 227811690 7781354 68867..70864 1 NC_012580.1 protease II 70864 ptrB 7781354 ptrB Vibrio cholerae M66-2 protease II YP_002811700.1 68867 D 579112 CDS YP_002811701.1 227811691 7781355 70864..73005 1 NC_012580.1 heme receptor HutR 73005 hutR 7781355 hutR Vibrio cholerae M66-2 heme receptor HutR YP_002811701.1 70864 D 579112 CDS YP_002811702.1 227811692 7781356 73015..75321 1 NC_012580.1 hypothetical protein 75321 7781356 VCM66_A0062 Vibrio cholerae M66-2 hypothetical protein YP_002811702.1 73015 D 579112 CDS YP_002811703.1 227811693 7781357 75318..76760 1 NC_012580.1 hypothetical protein 76760 7781357 VCM66_A0063 Vibrio cholerae M66-2 hypothetical protein YP_002811703.1 75318 D 579112 CDS YP_002811704.1 227811694 7781358 76757..77317 1 NC_012580.1 hypothetical protein 77317 7781358 VCM66_A0064 Vibrio cholerae M66-2 hypothetical protein YP_002811704.1 76757 D 579112 CDS YP_002811705.1 227811695 7781359 complement(77451..79094) 1 NC_012580.1 methyl-accepting chemotaxis protein 79094 7781359 VCM66_A0065 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811705.1 77451 R 579112 CDS YP_002811706.1 227811696 7781360 79241..79339 1 NC_012580.1 hypothetical protein 79339 7781360 VCM66_A0066 Vibrio cholerae M66-2 hypothetical protein YP_002811706.1 79241 D 579112 CDS YP_002811707.1 227811697 7781361 79387..80286 1 NC_012580.1 phosphate ABC transporter substrate-binding protein 80286 pstS 7781361 pstS Vibrio cholerae M66-2 phosphate ABC transporter substrate-binding protein YP_002811707.1 79387 D 579112 CDS YP_002811708.1 227811698 7781362 80301..81284 1 NC_012580.1 phosphate ABC transporter permease 81284 pstC-2 7781362 pstC-2 Vibrio cholerae M66-2 phosphate ABC transporter permease YP_002811708.1 80301 D 579112 CDS YP_002811709.1 227811699 7781363 81284..82153 1 NC_012580.1 phosphate ABC transporter permease 82153 pstA-2 7781363 pstA-2 Vibrio cholerae M66-2 phosphate ABC transporter permease YP_002811709.1 81284 D 579112 CDS YP_002811710.1 227811700 7781364 82182..82937 1 NC_012580.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 82937 pstB-2 7781364 pstB-2 Vibrio cholerae M66-2 phosphate ABC transporter ATP-binding protein YP_002811710.1 82182 D 579112 CDS YP_002811711.1 227811701 7781366 complement(84081..84548) 1 NC_012580.1 hypothetical protein 84548 7781366 VCM66_A0072 Vibrio cholerae M66-2 hypothetical protein YP_002811711.1 84081 R 579112 CDS YP_002811712.1 227811702 7781367 84430..84675 1 NC_012580.1 putative Hemolysin secretion protein D 84675 7781367 VCM66_A0073 Vibrio cholerae M66-2 putative Hemolysin secretion protein D YP_002811712.1 84430 D 579112 CDS YP_002811713.1 227811703 7781368 complement(84839..86215) 1 NC_012580.1 hypothetical protein 86215 7781368 VCM66_A0074 Vibrio cholerae M66-2 hypothetical protein YP_002811713.1 84839 R 579112 CDS YP_002811714.1 227811704 7781369 complement(86650..88311) 1 NC_012580.1 sulfate permease family protein 88311 7781369 VCM66_A0075 Vibrio cholerae M66-2 sulfate permease family protein YP_002811714.1 86650 R 579112 CDS YP_002811715.1 227811705 7781370 88616..88948 1 NC_012580.1 hypothetical protein 88948 7781370 VCM66_A0076 Vibrio cholerae M66-2 hypothetical protein YP_002811715.1 88616 D 579112 CDS YP_002811716.1 227811706 7781371 89140..90432 1 NC_012580.1 hypothetical protein 90432 7781371 VCM66_A0077 Vibrio cholerae M66-2 hypothetical protein YP_002811716.1 89140 D 579112 CDS YP_002811717.1 227811707 7781372 complement(90550..92373) 1 NC_012580.1 GGDEF family protein 92373 7781372 VCM66_A0078 Vibrio cholerae M66-2 GGDEF family protein YP_002811717.1 90550 R 579112 CDS YP_002811718.1 227811708 7781373 complement(92596..93483) 1 NC_012580.1 LysR family transcriptional regulator 93483 7781373 VCM66_A0080 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002811718.1 92596 R 579112 CDS YP_002811719.1 227811709 7781374 93573..94784 1 NC_012580.1 multidrug resistance protein D 94784 emrD-1 7781374 emrD-1 Vibrio cholerae M66-2 multidrug resistance protein D YP_002811719.1 93573 D 579112 CDS YP_002811720.1 227811710 7781375 complement(94826..95272) 1 NC_012580.1 soxR protein 95272 soxR 7781375 soxR Vibrio cholerae M66-2 soxR protein YP_002811720.1 94826 R 579112 CDS YP_002811721.1 227811711 7781376 95451..96653 1 NC_012580.1 hypothetical protein 96653 7781376 VCM66_A0083 Vibrio cholerae M66-2 hypothetical protein YP_002811721.1 95451 D 579112 CDS YP_002811722.1 227811712 7781377 96754..97134 1 NC_012580.1 hypothetical protein 97134 7781377 VCM66_A0084 Vibrio cholerae M66-2 hypothetical protein YP_002811722.1 96754 D 579112 CDS YP_002811723.1 227811713 7781378 97208..97372 1 NC_012580.1 hypothetical protein 97372 7781378 VCM66_A0085 Vibrio cholerae M66-2 hypothetical protein YP_002811723.1 97208 D 579112 CDS YP_002811724.1 227811714 7781379 complement(97501..98811) 1 NC_012580.1 proton/glutamate symporter 98811 gltP-2 7781379 gltP-2 Vibrio cholerae M66-2 proton/glutamate symporter YP_002811724.1 97501 R 579112 CDS YP_002811725.1 227811715 7781380 98839..98967 1 NC_012580.1 hypothetical protein 98967 7781380 VCM66_A0087 Vibrio cholerae M66-2 hypothetical protein YP_002811725.1 98839 D 579112 CDS YP_002811726.1 227811716 7781381 complement(99067..99960) 1 NC_012580.1 hypothetical protein 99960 7781381 VCM66_A0088 Vibrio cholerae M66-2 hypothetical protein YP_002811726.1 99067 R 579112 CDS YP_002811727.1 227811717 7781382 100190..100486 1 NC_012580.1 hypothetical protein 100486 7781382 VCM66_A0089 Vibrio cholerae M66-2 hypothetical protein YP_002811727.1 100190 D 579112 CDS YP_002811728.1 227811718 7781383 complement(100657..101286) 1 NC_012580.1 hypothetical protein 101286 7781383 VCM66_A0090 Vibrio cholerae M66-2 hypothetical protein YP_002811728.1 100657 R 579112 CDS YP_002811729.1 227811719 7781384 101386..101559 1 NC_012580.1 hypothetical protein 101559 7781384 VCM66_A0091 Vibrio cholerae M66-2 hypothetical protein YP_002811729.1 101386 D 579112 CDS YP_002811730.1 227811720 7781385 101787..102143 1 NC_012580.1 hypothetical protein 102143 7781385 VCM66_A0092 Vibrio cholerae M66-2 hypothetical protein YP_002811730.1 101787 D 579112 CDS YP_002811731.1 227811721 7781386 102412..103110 1 NC_012580.1 hypothetical protein 103110 7781386 VCM66_A0093 Vibrio cholerae M66-2 hypothetical protein YP_002811731.1 102412 D 579112 CDS YP_002811732.1 227811722 7781387 103153..104376 1 NC_012580.1 hypothetical protein 104376 7781387 VCM66_A0094 Vibrio cholerae M66-2 hypothetical protein YP_002811732.1 103153 D 579112 CDS YP_002811733.1 227811723 7781388 complement(104389..105105) 1 NC_012580.1 hypothetical protein 105105 7781388 VCM66_A0095 Vibrio cholerae M66-2 hypothetical protein YP_002811733.1 104389 R 579112 CDS YP_002811734.1 227811724 7781389 105504..106811 1 NC_012580.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 106811 pncB 7781389 pncB Vibrio cholerae M66-2 nicotinate phosphoribosyltransferase YP_002811734.1 105504 D 579112 CDS YP_002811735.1 227811725 7781390 106842..107882 1 NC_012580.1 oxidoreductase, Gfo/Idh/MocA family 107882 7781390 VCM66_A0097 Vibrio cholerae M66-2 oxidoreductase, Gfo/Idh/MocA family YP_002811735.1 106842 D 579112 CDS YP_002811736.1 227811726 7781391 complement(107919..108290) 1 NC_012580.1 phage shock protein E 108290 pspE 7781391 pspE Vibrio cholerae M66-2 phage shock protein E YP_002811736.1 107919 R 579112 CDS YP_002811737.1 227811727 7781392 complement(108290..109846) 1 NC_012580.1 hypothetical protein 109846 7781392 VCM66_A0099 Vibrio cholerae M66-2 hypothetical protein YP_002811737.1 108290 R 579112 CDS YP_002811738.1 227811728 7781393 complement(110022..110681) 1 NC_012580.1 CbbY family protein 110681 7781393 VCM66_A0100 Vibrio cholerae M66-2 CbbY family protein YP_002811738.1 110022 R 579112 CDS YP_002811739.1 227811729 7781394 110862..112640 1 NC_012580.1 sulfate permease family protein 112640 7781394 VCM66_A0101 Vibrio cholerae M66-2 sulfate permease family protein YP_002811739.1 110862 D 579112 CDS YP_002811740.1 227811730 7781395 complement(112682..114361) 1 NC_012580.1 ribosomal large subunit pseudouridine synthase A 114361 rluA-2 7781395 rluA-2 Vibrio cholerae M66-2 ribosomal large subunit pseudouridine synthase A YP_002811740.1 112682 R 579112 CDS YP_002811741.1 227811731 7781396 115133..115417 1 NC_012580.1 hypothetical protein 115417 7781396 VCM66_A0103 Vibrio cholerae M66-2 hypothetical protein YP_002811741.1 115133 D 579112 CDS YP_002811742.1 227811732 7781397 115362..116405 1 NC_012580.1 hypothetical protein 116405 7781397 VCM66_A0104 Vibrio cholerae M66-2 hypothetical protein YP_002811742.1 115362 D 579112 CDS YP_002811743.1 227811733 7781398 116837..117343 1 NC_012580.1 hypothetical protein 117343 7781398 VCM66_A0105 Vibrio cholerae M66-2 hypothetical protein YP_002811743.1 116837 D 579112 CDS YP_002811744.1 227811734 7781399 117384..118862 1 NC_012580.1 hypothetical protein 118862 7781399 VCM66_A0106 Vibrio cholerae M66-2 hypothetical protein YP_002811744.1 117384 D 579112 CDS YP_002811745.1 227811735 7781400 118865..119302 1 NC_012580.1 hypothetical protein 119302 7781400 VCM66_A0107 Vibrio cholerae M66-2 hypothetical protein YP_002811745.1 118865 D 579112 CDS YP_002811746.1 227811736 7781401 119308..121077 1 NC_012580.1 hypothetical protein 121077 7781401 VCM66_A0108 Vibrio cholerae M66-2 hypothetical protein YP_002811746.1 119308 D 579112 CDS YP_002811747.1 227811737 7781402 121041..122057 1 NC_012580.1 hypothetical protein 122057 7781402 VCM66_A0109 Vibrio cholerae M66-2 hypothetical protein YP_002811747.1 121041 D 579112 CDS YP_002811748.1 227811738 7781403 122060..123547 1 NC_012580.1 hypothetical protein 123547 7781403 VCM66_A0110 Vibrio cholerae M66-2 hypothetical protein YP_002811748.1 122060 D 579112 CDS YP_002811749.1 227811739 7781404 123550..124026 1 NC_012580.1 hypothetical protein 124026 7781404 VCM66_A0111 Vibrio cholerae M66-2 hypothetical protein YP_002811749.1 123550 D 579112 CDS YP_002811750.1 227811740 7781405 124033..125367 1 NC_012580.1 hypothetical protein 125367 7781405 VCM66_A0112 Vibrio cholerae M66-2 hypothetical protein YP_002811750.1 124033 D 579112 CDS YP_002811751.1 227811741 7781406 125370..126143 1 NC_012580.1 hypothetical protein 126143 7781406 VCM66_A0113 Vibrio cholerae M66-2 hypothetical protein YP_002811751.1 125370 D 579112 CDS YP_002811752.1 227811742 7781407 126169..128778 1 NC_012580.1 clpB protein 128778 clpB-2 7781407 clpB-2 Vibrio cholerae M66-2 clpB protein YP_002811752.1 126169 D 579112 CDS YP_002811753.1 227811743 7781408 128781..130373 1 NC_012580.1 sigma-54 dependent transcriptional regulator 130373 7781408 VCM66_A0115 Vibrio cholerae M66-2 sigma-54 dependent transcriptional regulator YP_002811753.1 128781 D 579112 CDS YP_002811754.1 227811744 7781409 130343..131026 1 NC_012580.1 hypothetical protein 131026 7781409 VCM66_A0116 Vibrio cholerae M66-2 hypothetical protein YP_002811754.1 130343 D 579112 CDS YP_002811755.1 227811745 7781410 131036..132445 1 NC_012580.1 hypothetical protein 132445 7781410 VCM66_A0117 Vibrio cholerae M66-2 hypothetical protein YP_002811755.1 131036 D 579112 CDS YP_002811756.1 227811746 7781411 132461..136006 1 NC_012580.1 IcmF-related protein 136006 7781411 VCM66_A0118 Vibrio cholerae M66-2 IcmF-related protein YP_002811756.1 132461 D 579112 CDS YP_002811757.1 227811747 7781412 136054..137319 1 NC_012580.1 hypothetical protein 137319 7781412 VCM66_A0119 Vibrio cholerae M66-2 hypothetical protein YP_002811757.1 136054 D 579112 CDS YP_002811758.1 227811748 7781413 137370..137612 1 NC_012580.1 hypothetical protein 137612 7781413 VCM66_A0120 Vibrio cholerae M66-2 hypothetical protein YP_002811758.1 137370 D 579112 CDS YP_002811759.1 227811749 7781414 137572..140625 1 NC_012580.1 vgrG protein 140625 vgrG-3 7781414 vgrG-3 Vibrio cholerae M66-2 vgrG protein YP_002811759.1 137572 D 579112 CDS YP_002811760.1 227811750 7781415 140622..140990 1 NC_012580.1 hypothetical protein 140990 7781415 VCM66_A0122 Vibrio cholerae M66-2 hypothetical protein YP_002811760.1 140622 D 579112 CDS YP_002811761.1 227811751 7781416 complement(141138..141398) 1 NC_012580.1 hypothetical protein 141398 7781416 VCM66_A0123 Vibrio cholerae M66-2 hypothetical protein YP_002811761.1 141138 R 579112 CDS YP_002811762.1 227811752 7781417 141373..141582 1 NC_012580.1 hypothetical protein 141582 7781417 VCM66_A0124 Vibrio cholerae M66-2 hypothetical protein YP_002811762.1 141373 D 579112 CDS YP_002811763.1 227811753 7781418 141631..142101 1 NC_012580.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 142101 rbsD 7781418 rbsD Vibrio cholerae M66-2 D-ribose pyranase YP_002811763.1 141631 D 579112 CDS YP_002811764.1 227811754 7781419 142128..143630 1 NC_012580.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 143630 rbsA 7781419 rbsA Vibrio cholerae M66-2 D-ribose transporter ATP binding protein YP_002811764.1 142128 D 579112 CDS YP_002811765.1 227811755 7781420 143627..144628 1 NC_012580.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 144628 rbsC 7781420 rbsC Vibrio cholerae M66-2 ribose ABC transporter permease protein YP_002811765.1 143627 D 579112 CDS YP_002811766.1 227811756 7781421 144683..145567 1 NC_012580.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 145567 rbsB 7781421 rbsB Vibrio cholerae M66-2 D-ribose transporter subunit RbsB YP_002811766.1 144683 D 579112 CDS YP_002811767.1 227811757 7781422 145706..146626 1 NC_012580.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 146626 rbsK 7781422 rbsK Vibrio cholerae M66-2 ribokinase YP_002811767.1 145706 D 579112 CDS YP_002811768.1 227811758 7781423 146637..147641 1 NC_012580.1 ribose operon repressor 147641 rbsR 7781423 rbsR Vibrio cholerae M66-2 ribose operon repressor YP_002811768.1 146637 D 579112 CDS YP_002811769.1 227811759 7781424 147767..148501 1 NC_012580.1 pnuC protein 148501 pnuC 7781424 pnuC Vibrio cholerae M66-2 pnuC protein YP_002811769.1 147767 D 579112 CDS YP_002811770.1 227811760 7781425 148498..149229 1 NC_012580.1 uridine phosphorylase 149229 udp-2 7781425 udp-2 Vibrio cholerae M66-2 uridine phosphorylase YP_002811770.1 148498 D 579112 CDS YP_002811771.1 227811761 7781426 149369..150049 1 NC_012580.1 putative cyclic nucleotide binding protein 150049 7781426 VCM66_A0133 Vibrio cholerae M66-2 putative cyclic nucleotide binding protein YP_002811771.1 149369 D 579112 CDS YP_002811772.1 227811762 7781427 complement(150102..151217) 1 NC_012580.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 151217 glpQ 7781427 glpQ Vibrio cholerae M66-2 glycerophosphodiester phosphodiesterase YP_002811772.1 150102 R 579112 CDS YP_002811773.1 227811763 7781428 complement(151323..152732) 1 NC_012580.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 152732 glpT 7781428 glpT Vibrio cholerae M66-2 sn-glycerol-3-phosphate transporter YP_002811773.1 151323 R 579112 CDS YP_002811774.1 227811764 7781429 complement(152828..152935) 1 NC_012580.1 hypothetical protein 152935 7781429 VCM66_A0136 Vibrio cholerae M66-2 hypothetical protein YP_002811774.1 152828 R 579112 CDS YP_002811775.1 227811765 7781430 complement(153107..153454) 1 NC_012580.1 hypothetical protein 153454 7781430 VCM66_A0137 Vibrio cholerae M66-2 hypothetical protein YP_002811775.1 153107 R 579112 CDS YP_002811776.1 227811766 7781431 153862..155070 1 NC_012580.1 spindolin-related protein 155070 7781431 VCM66_A0138 Vibrio cholerae M66-2 spindolin-related protein YP_002811776.1 153862 D 579112 CDS YP_002811777.1 227811767 7781432 complement(155185..157239) 1 NC_012580.1 putative C4-dicarboxylate transport sensor protein 157239 7781432 VCM66_A0139 Vibrio cholerae M66-2 putative C4-dicarboxylate transport sensor protein YP_002811777.1 155185 R 579112 CDS YP_002811778.1 227811768 7781433 157529..158881 1 NC_012580.1 C4-dicarboxylate transport transcriptional regulatory protein 158881 dctD-2 7781433 dctD-2 Vibrio cholerae M66-2 C4-dicarboxylate transport transcriptional regulatory protein YP_002811778.1 157529 D 579112 CDS YP_002811779.1 227811769 7781434 158947..159057 1 NC_012580.1 hypothetical protein 159057 7781434 VCM66_A0141 Vibrio cholerae M66-2 hypothetical protein YP_002811779.1 158947 D 579112 CDS YP_002811780.1 227811770 7781435 159135..160190 1 NC_012580.1 immunogenic protein 160190 7781435 VCM66_A0142 Vibrio cholerae M66-2 immunogenic protein YP_002811780.1 159135 D 579112 CDS YP_002811781.1 227811771 7781436 complement(160159..160287) 1 NC_012580.1 hypothetical protein 160287 7781436 VCM66_A0143 Vibrio cholerae M66-2 hypothetical protein YP_002811781.1 160159 R 579112 CDS YP_002811782.1 227811772 7781437 160340..162505 1 NC_012580.1 putative TRAP transporter large permease protein 162505 7781437 VCM66_A0144 Vibrio cholerae M66-2 putative TRAP transporter large permease protein YP_002811782.1 160340 D 579112 CDS YP_002811783.1 227811773 7781438 162502..163713 1 NC_012580.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 163713 7781438 VCM66_A0145 Vibrio cholerae M66-2 hydroxyglutarate oxidase YP_002811783.1 162502 D 579112 CDS YP_002811784.1 227811774 7781439 163822..167829 1 NC_012580.1 TagA-related protein 167829 7781439 VCM66_A0146 Vibrio cholerae M66-2 TagA-related protein YP_002811784.1 163822 D 579112 CDS YP_002811785.1 227811775 7781440 167854..167961 1 NC_012580.1 hypothetical protein 167961 7781440 VCM66_A0147 Vibrio cholerae M66-2 hypothetical protein YP_002811785.1 167854 D 579112 CDS YP_002811786.1 227811776 7781441 167977..168483 1 NC_012580.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 168483 def-2 7781441 def-2 Vibrio cholerae M66-2 peptide deformylase YP_002811786.1 167977 D 579112 CDS YP_002811787.1 227811777 7781442 168612..169964 1 NC_012580.1 putative oxidoreductase 169964 7781442 VCM66_A0149 Vibrio cholerae M66-2 putative oxidoreductase YP_002811787.1 168612 D 579112 CDS YP_002811788.1 227811778 7781443 complement(170039..170362) 1 NC_012580.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 170362 7781443 VCM66_A0150 Vibrio cholerae M66-2 putative monovalent cation/H+ antiporter subunit G YP_002811788.1 170039 R 579112 CDS YP_002811789.1 227811779 7781444 complement(170362..170673) 1 NC_012580.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 170673 7781444 VCM66_A0151 Vibrio cholerae M66-2 putative monovalent cation/H+ antiporter subunit F YP_002811789.1 170362 R 579112 CDS YP_002811790.1 227811780 7781445 complement(170633..171109) 1 NC_012580.1 hypothetical protein 171109 7781445 VCM66_A0152 Vibrio cholerae M66-2 hypothetical protein YP_002811790.1 170633 R 579112 CDS YP_002811791.1 227811781 7781446 complement(171106..172602) 1 NC_012580.1 putative NADH dehydrogenase 172602 7781446 VCM66_A0153 Vibrio cholerae M66-2 putative NADH dehydrogenase YP_002811791.1 171106 R 579112 CDS YP_002811792.1 227811782 7781447 complement(172599..172952) 1 NC_012580.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 172952 7781447 VCM66_A0154 Vibrio cholerae M66-2 putative monovalent cation/H+ antiporter subunit C YP_002811792.1 172599 R 579112 CDS YP_002811793.1 227811783 7781448 complement(172952..175627) 1 NC_012580.1 putative NADH dehydrogenase 175627 7781448 VCM66_A0155 Vibrio cholerae M66-2 putative NADH dehydrogenase YP_002811793.1 172952 R 579112 CDS YP_002811794.1 227811784 7781449 complement(175774..175974) 1 NC_012580.1 hypothetical protein 175974 7781449 VCM66_A0156 Vibrio cholerae M66-2 hypothetical protein YP_002811794.1 175774 R 579112 CDS YP_002811795.1 227811785 7781450 complement(176046..176987) 1 NC_012580.1 hypothetical protein 176987 7781450 VCM66_A0157 Vibrio cholerae M66-2 hypothetical protein YP_002811795.1 176046 R 579112 CDS YP_002811796.1 227811786 7781451 complement(177183..178418) 1 NC_012580.1 tryptophan-specific transport protein 178418 mtr 7781451 mtr Vibrio cholerae M66-2 tryptophan-specific transport protein YP_002811796.1 177183 R 579112 CDS YP_002811797.1 227811787 7781452 complement(178497..179915) 1 NC_012580.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 179915 tnaA 7781452 tnaA Vibrio cholerae M66-2 tryptophanase YP_002811797.1 178497 R 579112 CDS YP_002811798.1 227811788 7781453 complement(180481..180687) 1 NC_012580.1 hypothetical protein 180687 7781453 VCM66_A0160 Vibrio cholerae M66-2 hypothetical protein YP_002811798.1 180481 R 579112 CDS YP_002811799.1 227811789 7781454 180696..180908 1 NC_012580.1 hypothetical protein 180908 7781454 VCM66_A0161 Vibrio cholerae M66-2 hypothetical protein YP_002811799.1 180696 D 579112 CDS YP_002811800.1 227811790 7781455 complement(180978..181562) 1 NC_012580.1 hypothetical protein 181562 7781455 VCM66_A0162 Vibrio cholerae M66-2 hypothetical protein YP_002811800.1 180978 R 579112 CDS YP_002811801.1 227811791 7781456 181869..184001 1 NC_012580.1 GGDEF family protein 184001 7781456 VCM66_A0163 Vibrio cholerae M66-2 GGDEF family protein YP_002811801.1 181869 D 579112 CDS YP_002811802.1 227811792 7781457 184247..184459 1 NC_012580.1 cold shock transcriptional regulator CspA 184459 cspA 7781457 cspA Vibrio cholerae M66-2 cold shock transcriptional regulator CspA YP_002811802.1 184247 D 579112 CDS YP_002811803.1 227811793 7781458 complement(184762..185550) 1 NC_012580.1 hypothetical protein 185550 7781458 VCM66_A0165 Vibrio cholerae M66-2 hypothetical protein YP_002811803.1 184762 R 579112 CDS YP_002811804.1 227811794 7781459 complement(185639..187291) 1 NC_012580.1 hypothetical protein 187291 7781459 VCM66_A0166 Vibrio cholerae M66-2 hypothetical protein YP_002811804.1 185639 R 579112 CDS YP_002811805.1 227811795 7781460 complement(187285..189171) 1 NC_012580.1 hypothetical protein 189171 7781460 VCM66_A0167 Vibrio cholerae M66-2 hypothetical protein YP_002811805.1 187285 R 579112 CDS YP_002811806.1 227811796 7781461 complement(189173..190129) 1 NC_012580.1 hypothetical protein 190129 7781461 VCM66_A0168 Vibrio cholerae M66-2 hypothetical protein YP_002811806.1 189173 R 579112 CDS YP_002811807.1 227811797 7781462 complement(190116..190604) 1 NC_012580.1 hypothetical protein 190604 7781462 VCM66_A0169 Vibrio cholerae M66-2 hypothetical protein YP_002811807.1 190116 R 579112 CDS YP_002811808.1 227811798 7781463 complement(190601..191533) 1 NC_012580.1 hypothetical protein 191533 7781463 VCM66_A0170 Vibrio cholerae M66-2 hypothetical protein YP_002811808.1 190601 R 579112 CDS YP_002811809.1 227811799 7781464 complement(191537..192493) 1 NC_012580.1 MoxR-related protein 192493 7781464 VCM66_A0171 Vibrio cholerae M66-2 MoxR-related protein YP_002811809.1 191537 R 579112 CDS YP_002811810.1 227811800 7781465 192795..194711 1 NC_012580.1 methyl-accepting chemotaxis protein 194711 7781465 VCM66_A0172 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811810.1 192795 D 579112 CDS YP_002811811.1 227811801 7781466 194768..194971 1 NC_012580.1 hypothetical protein 194971 7781466 VCM66_A0173 Vibrio cholerae M66-2 hypothetical protein YP_002811811.1 194768 D 579112 CDS YP_002811812.1 227811802 7781467 complement(195247..195900) 1 NC_012580.1 frnE protein 195900 frnE 7781467 frnE Vibrio cholerae M66-2 frnE protein YP_002811812.1 195247 R 579112 CDS YP_002811813.1 227811803 7781468 196547..197755 1 NC_012580.1 NupC family protein 197755 7781468 VCM66_A0175 Vibrio cholerae M66-2 NupC family protein YP_002811813.1 196547 D 579112 CDS YP_002811814.1 227811804 7781469 197990..199222 1 NC_012580.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 199222 pepT 7781469 pepT Vibrio cholerae M66-2 peptidase T YP_002811814.1 197990 D 579112 CDS YP_002811815.1 227811805 7781470 199394..200269 1 NC_012580.1 hypothetical protein 200269 7781470 VCM66_A0177 Vibrio cholerae M66-2 hypothetical protein YP_002811815.1 199394 D 579112 CDS YP_002811816.1 227811806 7781471 complement(200266..201858) 1 NC_012580.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator 201858 7781471 VCM66_A0178 Vibrio cholerae M66-2 anaerobic nitric oxide reductase transcription regulator YP_002811816.1 200266 R 579112 CDS YP_002811817.1 227811807 7781472 202049..203233 1 NC_012580.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 203233 hmpA 7781472 hmpA Vibrio cholerae M66-2 nitric oxide dioxygenase YP_002811817.1 202049 D 579112 CDS YP_002811818.1 227811808 7781473 complement(203377..203586) 1 NC_012580.1 cold shock DNA-binding domain protein 203586 7781473 VCM66_A0180 Vibrio cholerae M66-2 cold shock DNA-binding domain protein YP_002811818.1 203377 R 579112 CDS YP_002811819.1 227811809 7781474 203945..204172 1 NC_012580.1 hypothetical protein 204172 7781474 VCM66_A0181 Vibrio cholerae M66-2 hypothetical protein YP_002811819.1 203945 D 579112 CDS YP_002811820.1 227811810 7781475 204560..204937 1 NC_012580.1 hypothetical protein 204937 7781475 VCM66_A0182 Vibrio cholerae M66-2 hypothetical protein YP_002811820.1 204560 D 579112 CDS YP_002811821.1 227811811 7781476 complement(204963..205094) 1 NC_012580.1 hypothetical protein 205094 7781476 VCM66_A0183 Vibrio cholerae M66-2 hypothetical protein YP_002811821.1 204963 R 579112 CDS YP_002811822.1 227811812 7781477 205172..205450 1 NC_012580.1 hypothetical protein 205450 7781477 VCM66_A0184 Vibrio cholerae M66-2 hypothetical protein YP_002811822.1 205172 D 579112 CDS YP_002811823.1 227811813 7781478 205537..206541 1 NC_012580.1 response regulator 206541 7781478 VCM66_A0185 Vibrio cholerae M66-2 response regulator YP_002811823.1 205537 D 579112 CDS YP_002811824.1 227811814 7781479 206541..206987 1 NC_012580.1 hypothetical protein 206987 7781479 VCM66_A0186 Vibrio cholerae M66-2 hypothetical protein YP_002811824.1 206541 D 579112 CDS YP_002811825.1 227811815 7781480 207025..208509 1 NC_012580.1 hypothetical protein 208509 7781480 VCM66_A0187 Vibrio cholerae M66-2 hypothetical protein YP_002811825.1 207025 D 579112 CDS YP_002811826.1 227811816 7781481 complement(208498..209493) 1 NC_012580.1 D-lactate dehydrogenase 209493 ldhA 7781481 ldhA Vibrio cholerae M66-2 D-lactate dehydrogenase YP_002811826.1 208498 R 579112 CDS YP_002811827.1 227811817 7781482 209676..211019 1 NC_012580.1 putative Na+/H+ antiporter 211019 7781482 VCM66_A0189 Vibrio cholerae M66-2 putative Na+/H+ antiporter YP_002811827.1 209676 D 579112 CDS YP_002811828.1 227811818 7781483 complement(211021..211863) 1 NC_012580.1 putative potassium channel protein 211863 7781483 VCM66_A0190 Vibrio cholerae M66-2 putative potassium channel protein YP_002811828.1 211021 R 579112 CDS YP_002811829.1 227811819 7781484 complement(211929..212477) 1 NC_012580.1 hypothetical protein 212477 7781484 VCM66_A0191 Vibrio cholerae M66-2 hypothetical protein YP_002811829.1 211929 R 579112 CDS YP_002811830.1 227811820 7781485 complement(212593..212970) 1 NC_012580.1 hypothetical protein 212970 7781485 VCM66_A0192 Vibrio cholerae M66-2 hypothetical protein YP_002811830.1 212593 R 579112 CDS YP_002811831.1 227811821 7781486 213135..214178 1 NC_012580.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 214178 guaC 7781486 guaC Vibrio cholerae M66-2 guanosine 5'-monophosphate oxidoreductase YP_002811831.1 213135 D 579112 CDS YP_002811832.1 227811822 7781487 214502..215653 1 NC_012580.1 putative site-specific DNA-methyltransferase 215653 7781487 VCM66_A0194 Vibrio cholerae M66-2 putative site-specific DNA-methyltransferase YP_002811832.1 214502 D 579112 CDS YP_002811833.1 227811823 7781488 215777..217693 1 NC_012580.1 hypothetical protein 217693 7781488 VCM66_A0195 Vibrio cholerae M66-2 hypothetical protein YP_002811833.1 215777 D 579112 CDS YP_002811834.1 227811824 7781489 217686..218810 1 NC_012580.1 hypothetical protein 218810 7781489 VCM66_A0196 Vibrio cholerae M66-2 hypothetical protein YP_002811834.1 217686 D 579112 CDS YP_002811835.1 227811825 7781490 218807..219685 1 NC_012580.1 hypothetical protein 219685 7781490 VCM66_A0197 Vibrio cholerae M66-2 hypothetical protein YP_002811835.1 218807 D 579112 CDS YP_002811836.1 227811826 7781491 complement(219753..220190) 1 NC_012580.1 IS1004 transposase 220190 tnpA 7781491 tnpA Vibrio cholerae M66-2 IS1004 transposase YP_002811836.1 219753 R 579112 CDS YP_002811837.1 227811827 7781492 complement(220695..222050) 1 NC_012580.1 ATP-dependent RNA helicase RhlE 222050 rhlE-2 7781492 rhlE-2 Vibrio cholerae M66-2 ATP-dependent RNA helicase RhlE YP_002811837.1 220695 R 579112 CDS YP_002811838.1 227811828 7781493 complement(222240..223568) 1 NC_012580.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 223568 dcuB 7781493 dcuB Vibrio cholerae M66-2 anaerobic C4-dicarboxylate transporter YP_002811838.1 222240 R 579112 CDS YP_002811839.1 227811829 7781494 complement(223818..224648) 1 NC_012580.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 224648 nadE 7781494 nadE Vibrio cholerae M66-2 NAD synthetase YP_002811839.1 223818 R 579112 CDS YP_002811840.1 227811830 7781495 224751..225278 1 NC_012580.1 catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; nicotinic acid mononucleotide adenylyltransferase 225278 7781495 VCM66_A0204 Vibrio cholerae M66-2 nicotinic acid mononucleotide adenylyltransferase YP_002811840.1 224751 D 579112 CDS YP_002811841.1 227811831 7781496 225229..225411 1 NC_012580.1 hypothetical protein 225411 7781496 VCM66_A0205 Vibrio cholerae M66-2 hypothetical protein YP_002811841.1 225229 D 579112 CDS YP_002811842.1 227811832 7781497 225518..227086 1 NC_012580.1 putative response regulator 227086 7781497 VCM66_A0206 Vibrio cholerae M66-2 putative response regulator YP_002811842.1 225518 D 579112 CDS YP_002811843.1 227811833 7781498 complement(227144..229090) 1 NC_012580.1 sensory box sensor histidine kinase 229090 7781498 VCM66_A0207 Vibrio cholerae M66-2 sensory box sensor histidine kinase YP_002811843.1 227144 R 579112 CDS YP_002811844.1 227811834 7781499 229265..230314 1 NC_012580.1 hypothetical protein 230314 7781499 VCM66_A0208 Vibrio cholerae M66-2 hypothetical protein YP_002811844.1 229265 D 579112 CDS YP_002811845.1 227811835 7781500 complement(230392..231981) 1 NC_012580.1 hypothetical protein 231981 7781500 VCM66_A0209 Vibrio cholerae M66-2 hypothetical protein YP_002811845.1 230392 R 579112 CDS YP_002811846.1 227811836 7781501 complement(232376..233620) 1 NC_012580.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 233620 emrD 7781501 emrD Vibrio cholerae M66-2 multidrug resistance protein D YP_002811846.1 232376 R 579112 CDS YP_002811847.1 227811837 7781502 complement(233621..233779) 1 NC_012580.1 hypothetical protein 233779 7781502 VCM66_A0211 Vibrio cholerae M66-2 hypothetical protein YP_002811847.1 233621 R 579112 CDS YP_002811848.1 227811838 7781503 233834..234100 1 NC_012580.1 hypothetical protein 234100 7781503 VCM66_A0212 Vibrio cholerae M66-2 hypothetical protein YP_002811848.1 233834 D 579112 CDS YP_002811849.1 227811839 7781504 complement(234091..235170) 1 NC_012580.1 GGDEF family protein 235170 7781504 VCM66_A0213 Vibrio cholerae M66-2 GGDEF family protein YP_002811849.1 234091 R 579112 CDS YP_002811850.1 227811840 7781505 complement(235291..236547) 1 NC_012580.1 thermolabile hemolysin 236547 7781505 VCM66_A0214 Vibrio cholerae M66-2 thermolabile hemolysin YP_002811850.1 235291 R 579112 CDS YP_002811851.1 227811841 7781506 237517..239742 1 NC_012580.1 hemolysin 239742 hlyA 7781506 hlyA Vibrio cholerae M66-2 hemolysin YP_002811851.1 237517 D 579112 CDS YP_002811852.1 227811842 7781507 240041..241687 1 NC_012580.1 hemolysin secretion protein HylB 241687 hylB 7781507 hylB Vibrio cholerae M66-2 hemolysin secretion protein HylB YP_002811852.1 240041 D 579112 CDS YP_002811853.1 227811843 7781508 241954..242973 1 NC_012580.1 lactonizing lipase 242973 hlyC 7781508 hlyC Vibrio cholerae M66-2 lactonizing lipase YP_002811853.1 241954 D 579112 CDS YP_002811854.1 227811844 7781509 242983..243837 1 NC_012580.1 acts as a molecular chaperone to fold and export lipase A; lipase chaperone 243837 7781509 VCM66_A0218 Vibrio cholerae M66-2 lipase chaperone YP_002811854.1 242983 D 579112 CDS YP_002811855.1 227811845 7781510 complement(243913..246669) 1 NC_012580.1 protease 246669 prtV 7781510 prtV Vibrio cholerae M66-2 protease YP_002811855.1 243913 R 579112 CDS YP_002811856.1 227811846 7781511 complement(246754..247059) 1 NC_012580.1 hypothetical protein 247059 7781511 VCM66_A0220 Vibrio cholerae M66-2 hypothetical protein YP_002811856.1 246754 R 579112 CDS YP_002811857.1 227811847 7781512 247613..248377 1 NC_012580.1 hypothetical protein 248377 7781512 VCM66_A0221 Vibrio cholerae M66-2 hypothetical protein YP_002811857.1 247613 D 579112 CDS YP_002811858.1 227811848 7781513 complement(248537..248659) 1 NC_012580.1 hypothetical protein 248659 7781513 VCM66_A0222 Vibrio cholerae M66-2 hypothetical protein YP_002811858.1 248537 R 579112 CDS YP_002811859.1 227811849 7781514 248693..249694 1 NC_012580.1 vibriobactin and enterobactin ABC transporter, periplasmic vibriobactin/enterobactin-binding protein 249694 vctP 7781514 vctP Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter, periplasmic vibriobactin/enterobactin-binding protein YP_002811859.1 248693 D 579112 CDS YP_002811860.1 227811850 7781515 249747..250685 1 NC_012580.1 vibriobactin and enterobactin ABC transporter, permease protein 250685 vctD 7781515 vctD Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter, permease protein YP_002811860.1 249747 D 579112 CDS YP_002811861.1 227811851 7781516 250675..251625 1 NC_012580.1 vibriobactin and enterobactin ABC transporter, permease protein 251625 vctG 7781516 vctG Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter, permease protein YP_002811861.1 250675 D 579112 CDS YP_002811862.1 227811852 7781517 251628..252392 1 NC_012580.1 vibriobactin and enterobactin ABC transporter, ATP-binding protein 252392 vctC 7781517 vctC Vibrio cholerae M66-2 vibriobactin and enterobactin ABC transporter, ATP-binding protein YP_002811862.1 251628 D 579112 CDS YP_002811863.1 227811853 7781518 complement(252438..253514) 1 NC_012580.1 AraC family transcriptional regulator 253514 7781518 VCM66_A0227 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002811863.1 252438 R 579112 CDS YP_002811864.1 227811854 7781519 253541..255520 1 NC_012580.1 enterobactin receptor VctA 255520 vctA 7781519 vctA Vibrio cholerae M66-2 enterobactin receptor VctA YP_002811864.1 253541 D 579112 CDS YP_002811865.1 227811855 7781520 255578..255898 1 NC_012580.1 hypothetical protein 255898 7781520 VCM66_A0229 Vibrio cholerae M66-2 hypothetical protein YP_002811865.1 255578 D 579112 CDS YP_002811866.1 227811856 7781521 255914..256030 1 NC_012580.1 hypothetical protein 256030 7781521 VCM66_A0230 Vibrio cholerae M66-2 hypothetical protein YP_002811866.1 255914 D 579112 CDS YP_002811867.1 227811857 7781522 256168..257361 1 NC_012580.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 257361 ackA-2 7781522 ackA-2 Vibrio cholerae M66-2 acetate kinase YP_002811867.1 256168 D 579112 CDS YP_002811868.1 227811858 7781523 257442..257738 1 NC_012580.1 hypothetical protein 257738 7781523 VCM66_A0232 Vibrio cholerae M66-2 hypothetical protein YP_002811868.1 257442 D 579112 CDS YP_002811869.1 227811859 7781524 complement(257856..258425) 1 NC_012580.1 hypothetical protein 258425 7781524 VCM66_A0233 Vibrio cholerae M66-2 hypothetical protein YP_002811869.1 257856 R 579112 CDS YP_002811870.1 227811860 7781525 258670..260319 1 NC_012580.1 sensor histidine kinase 260319 7781525 VCM66_A0234 Vibrio cholerae M66-2 sensor histidine kinase YP_002811870.1 258670 D 579112 CDS YP_002811871.1 227811861 7781526 260300..260974 1 NC_012580.1 transcriptional regulator 260974 7781526 VCM66_A0235 Vibrio cholerae M66-2 transcriptional regulator YP_002811871.1 260300 D 579112 CDS YP_002811872.1 227811862 7781527 complement(260977..261606) 1 NC_012580.1 hypothetical protein 261606 7781527 VCM66_A0236 Vibrio cholerae M66-2 hypothetical protein YP_002811872.1 260977 R 579112 CDS YP_002811873.1 227811863 7781528 complement(261566..262450) 1 NC_012580.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 262450 7781528 VCM66_A0237 Vibrio cholerae M66-2 putative L-xylulose 5-phosphate 3-epimerase YP_002811873.1 261566 R 579112 CDS YP_002811874.1 227811864 7781529 complement(262462..263109) 1 NC_012580.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 263109 ulaD 7781529 ulaD Vibrio cholerae M66-2 3-keto-L-gulonate-6-phosphate decarboxylase YP_002811874.1 262462 R 579112 CDS YP_002811875.1 227811865 7781530 complement(263115..263936) 1 NC_012580.1 hypothetical protein 263936 7781530 VCM66_A0239 Vibrio cholerae M66-2 hypothetical protein YP_002811875.1 263115 R 579112 CDS YP_002811876.1 227811866 7781531 complement(263942..264634) 1 NC_012580.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 264634 araD 7781531 araD Vibrio cholerae M66-2 L-ribulose-5-phosphate 4-epimerase YP_002811876.1 263942 R 579112 CDS YP_002811877.1 227811867 7781532 complement(264643..265149) 1 NC_012580.1 PTS system, IIA component 265149 7781532 VCM66_A0241 Vibrio cholerae M66-2 PTS system, IIA component YP_002811877.1 264643 R 579112 CDS YP_002811878.1 227811868 7781533 complement(265247..267007) 1 NC_012580.1 PTS system ascorbate-specific transporter subunits IICB 267007 sgaT 7781533 sgaT Vibrio cholerae M66-2 PTS system ascorbate-specific transporter subunits IICB YP_002811878.1 265247 R 579112 CDS YP_002811879.1 227811869 7781534 267373..268128 1 NC_012580.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 268128 7781534 VCM66_A0243 Vibrio cholerae M66-2 transcriptional repressor UlaR YP_002811879.1 267373 D 579112 CDS YP_002811880.1 227811870 7781535 268255..269322 1 NC_012580.1 putative L-ascorbate 6-phosphate lactonase 269322 7781535 VCM66_A0244 Vibrio cholerae M66-2 putative L-ascorbate 6-phosphate lactonase YP_002811880.1 268255 D 579112 CDS YP_002811881.1 227811871 7781536 complement(269422..269955) 1 NC_012580.1 putative cytochrome b561 269955 7781536 VCM66_A0245 Vibrio cholerae M66-2 putative cytochrome b561 YP_002811881.1 269422 R 579112 CDS YP_002811882.1 227811872 7781537 complement(270128..271528) 1 NC_012580.1 alpha-amylase 271528 amy1 7781537 amy1 Vibrio cholerae M66-2 alpha-amylase YP_002811882.1 270128 R 579112 CDS YP_002811883.1 227811873 7781538 271668..271784 1 NC_012580.1 hypothetical protein 271784 7781538 VCM66_A0247 Vibrio cholerae M66-2 hypothetical protein YP_002811883.1 271668 D 579112 CDS YP_002811884.1 227811874 7781539 271744..271854 1 NC_012580.1 hypothetical protein 271854 7781539 VCM66_A0248 Vibrio cholerae M66-2 hypothetical protein YP_002811884.1 271744 D 579112 CDS YP_002811885.1 227811875 7781540 271861..272559 1 NC_012580.1 antibiotic acetyltransferase 272559 7781540 VCM66_A0249 Vibrio cholerae M66-2 antibiotic acetyltransferase YP_002811885.1 271861 D 579112 CDS YP_002811886.1 227811876 7781541 complement(272678..272944) 1 NC_012580.1 hypothetical protein 272944 7781541 VCM66_A0250 Vibrio cholerae M66-2 hypothetical protein YP_002811886.1 272678 R 579112 CDS YP_002811887.1 227811877 7781542 complement(273116..275347) 1 NC_012580.1 hypothetical protein 275347 7781542 VCM66_A0251 Vibrio cholerae M66-2 hypothetical protein YP_002811887.1 273116 R 579112 CDS YP_002811888.1 227811878 7781543 complement(275436..276266) 1 NC_012580.1 hypothetical protein 276266 7781543 VCM66_A0252 Vibrio cholerae M66-2 hypothetical protein YP_002811888.1 275436 R 579112 CDS YP_002811889.1 227811879 7781544 complement(276263..276934) 1 NC_012580.1 transcriptional regulator 276934 7781544 VCM66_A0253 Vibrio cholerae M66-2 transcriptional regulator YP_002811889.1 276263 R 579112 CDS YP_002811890.1 227811880 7781545 complement(276910..278364) 1 NC_012580.1 sensor histidine kinase 278364 7781545 VCM66_A0254 Vibrio cholerae M66-2 sensor histidine kinase YP_002811890.1 276910 R 579112 CDS YP_002811891.1 227811881 7781546 complement(278467..278979) 1 NC_012580.1 hypothetical protein 278979 7781546 VCM66_A0255 Vibrio cholerae M66-2 hypothetical protein YP_002811891.1 278467 R 579112 CDS YP_002811892.1 227811882 7781547 complement(279022..279150) 1 NC_012580.1 hypothetical protein 279150 7781547 VCM66_A0256 Vibrio cholerae M66-2 hypothetical protein YP_002811892.1 279022 R 579112 CDS YP_002811893.1 227811883 7781548 complement(279174..279683) 1 NC_012580.1 hypothetical protein 279683 7781548 VCM66_A0257 Vibrio cholerae M66-2 hypothetical protein YP_002811893.1 279174 R 579112 CDS YP_002811894.1 227811884 7781549 complement(279793..280203) 1 NC_012580.1 hypothetical protein 280203 7781549 VCM66_A0258 Vibrio cholerae M66-2 hypothetical protein YP_002811894.1 279793 R 579112 CDS YP_002811895.1 227811885 7781550 complement(280309..280851) 1 NC_012580.1 putative acetyltransferase 280851 7781550 VCM66_A0259 Vibrio cholerae M66-2 putative acetyltransferase YP_002811895.1 280309 R 579112 CDS YP_002811896.1 227811886 7781551 complement(280862..282040) 1 NC_012580.1 putative transcriptional regulator 282040 7781551 VCM66_A0260 Vibrio cholerae M66-2 putative transcriptional regulator YP_002811896.1 280862 R 579112 CDS YP_002811897.1 227811887 7781552 282224..282604 1 NC_012580.1 hypothetical protein 282604 7781552 VCM66_A0261 Vibrio cholerae M66-2 hypothetical protein YP_002811897.1 282224 D 579112 CDS YP_002811898.1 227811888 7781553 complement(282664..283437) 1 NC_012580.1 AraC family transcriptional regulator 283437 7781553 VCM66_A0262 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002811898.1 282664 R 579112 CDS YP_002811899.1 227811889 7781554 283539..284678 1 NC_012580.1 multidrug resistance protein D 284678 emrD-3 7781554 emrD-3 Vibrio cholerae M66-2 multidrug resistance protein D YP_002811899.1 283539 D 579112 CDS YP_002811900.1 227811890 7781555 284961..286892 1 NC_012580.1 methyl-accepting chemotaxis protein 286892 7781555 VCM66_A0264 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002811900.1 284961 D 579112 CDS YP_002811901.1 227811891 7781556 286908..288581 1 NC_012580.1 decarboxylase, group II 288581 7781556 VCM66_A0265 Vibrio cholerae M66-2 decarboxylase, group II YP_002811901.1 286908 D 579112 CDS YP_002811902.1 227811892 7781557 288746..289915 1 NC_012580.1 D-alanyl-D-alanine carboxypeptidase 289915 dacA-2 7781557 dacA-2 Vibrio cholerae M66-2 D-alanyl-D-alanine carboxypeptidase YP_002811902.1 288746 D 579112 CDS YP_002811903.1 227811893 7781558 290093..290440 1 NC_012580.1 hypothetical protein 290440 7781558 VCM66_A0267 Vibrio cholerae M66-2 hypothetical protein YP_002811903.1 290093 D 579112 CDS YP_002811904.1 227811894 7781559 complement(290535..290969) 1 NC_012580.1 hypothetical protein 290969 7781559 VCM66_A0268 Vibrio cholerae M66-2 hypothetical protein YP_002811904.1 290535 R 579112 CDS YP_002811905.1 227811895 7781560 291024..291158 1 NC_012580.1 hypothetical protein 291158 7781560 VCM66_A0269 Vibrio cholerae M66-2 hypothetical protein YP_002811905.1 291024 D 579112 CDS YP_002811906.1 227811896 7781561 291186..291905 1 NC_012580.1 carbonic anhydrase 291905 cah 7781561 cah Vibrio cholerae M66-2 carbonic anhydrase YP_002811906.1 291186 D 579112 CDS YP_002811907.1 227811897 7781562 complement(292407..293279) 1 NC_012580.1 ISVch4 transposase, OrfA 293279 7781562 VCM66_A0272 Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002811907.1 292407 R 579112 CDS YP_002811908.1 227811898 7781563 complement(293276..293620) 1 NC_012580.1 ISVch4 transposase, OrfB 293620 7781563 VCM66_A0273 Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002811908.1 293276 R 579112 CDS YP_002811909.1 227811899 7781564 complement(294070..296934) 1 NC_012580.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 296934 gcvP 7781564 gcvP Vibrio cholerae M66-2 glycine dehydrogenase YP_002811909.1 294070 R 579112 CDS YP_002811910.1 227811900 7781565 complement(297078..297458) 1 NC_012580.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 297458 gcvH 7781565 gcvH Vibrio cholerae M66-2 glycine cleavage system protein H YP_002811910.1 297078 R 579112 CDS YP_002811911.1 227811901 7781566 complement(297495..298802) 1 NC_012580.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 298802 glyA-2 7781566 glyA-2 Vibrio cholerae M66-2 serine hydroxymethyltransferase YP_002811911.1 297495 R 579112 CDS YP_002811912.1 227811902 7781567 299190..299813 1 NC_012580.1 transcriptional regulator, HTH_3 family 299813 7781567 VCM66_A0278 Vibrio cholerae M66-2 transcriptional regulator, HTH_3 family YP_002811912.1 299190 D 579112 CDS YP_002811913.1 227811903 7781568 300057..301187 1 NC_012580.1 glycine cleavage system T protein 301187 gcvT 7781568 gcvT Vibrio cholerae M66-2 glycine cleavage system T protein YP_002811913.1 300057 D 579112 CDS YP_002811914.1 227811904 7781569 301654..302811 1 NC_012580.1 putative integrase 302811 7781569 VCM66_A0280 Vibrio cholerae M66-2 putative integrase YP_002811914.1 301654 D 579112 CDS YP_002811915.1 227811905 7781570 302857..303837 1 NC_012580.1 ISVch5 transposase 303837 7781570 VCM66_A0281 Vibrio cholerae M66-2 ISVch5 transposase YP_002811915.1 302857 D 579112 CDS YP_002811916.1 227811906 7781571 304113..305348 1 NC_012580.1 hypothetical protein 305348 7781571 VCM66_A0282 Vibrio cholerae M66-2 hypothetical protein YP_002811916.1 304113 D 579112 CDS YP_002811917.1 227811907 7781572 305869..306399 1 NC_012580.1 hypothetical protein 306399 7781572 VCM66_A0283 Vibrio cholerae M66-2 hypothetical protein YP_002811917.1 305869 D 579112 CDS YP_002811918.1 227811908 7781573 306399..307070 1 NC_012580.1 hypothetical protein 307070 7781573 VCM66_A0284 Vibrio cholerae M66-2 hypothetical protein YP_002811918.1 306399 D 579112 CDS YP_002811919.1 227811909 7781574 307072..307422 1 NC_012580.1 hypothetical protein 307422 7781574 VCM66_A0285 Vibrio cholerae M66-2 hypothetical protein YP_002811919.1 307072 D 579112 CDS YP_002811920.1 227811910 7781575 307691..309619 1 NC_012580.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 309619 thrS 7781575 thrS Vibrio cholerae M66-2 threonyl-tRNA synthetase YP_002811920.1 307691 D 579112 CDS YP_002811921.1 227811911 7781576 309785..310174 1 NC_012580.1 initiation factor IF3 310174 infC 7781576 infC Vibrio cholerae M66-2 initiation factor IF3 YP_002811921.1 309785 D 579112 CDS YP_002811922.1 227811912 7781577 310278..310472 1 NC_012580.1 50S ribosomal protein L35 310472 rpmI 7781577 rpmI Vibrio cholerae M66-2 50S ribosomal protein L35 YP_002811922.1 310278 D 579112 CDS YP_002811923.1 227811913 7781578 310514..310867 1 NC_012580.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 310867 rplT 7781578 rplT Vibrio cholerae M66-2 50S ribosomal protein L20 YP_002811923.1 310514 D 579112 CDS YP_002811924.1 227811914 7781579 complement(310949..311911) 1 NC_012580.1 site-specific recombinase IntI4 311911 7781579 VCM66_A0290 Vibrio cholerae M66-2 site-specific recombinase IntI4 YP_002811924.1 310949 R 579112 CDS YP_002811925.1 227811915 7781580 312157..312549 1 NC_012580.1 hypothetical protein 312549 7781580 VCM66_A0291 Vibrio cholerae M66-2 hypothetical protein YP_002811925.1 312157 D 579112 CDS YP_002811926.1 227811916 7781581 312669..313064 1 NC_012580.1 hypothetical protein 313064 7781581 VCM66_A0292 Vibrio cholerae M66-2 hypothetical protein YP_002811926.1 312669 D 579112 CDS YP_002811927.1 227811917 7781582 complement(313256..313366) 1 NC_012580.1 hypothetical protein 313366 7781582 VCM66_A0293 Vibrio cholerae M66-2 hypothetical protein YP_002811927.1 313256 R 579112 CDS YP_002811928.1 227811918 7781583 313423..313518 1 NC_012580.1 hypothetical protein 313518 7781583 VCM66_A0294 Vibrio cholerae M66-2 hypothetical protein YP_002811928.1 313423 D 579112 CDS YP_002811929.1 227811919 7781584 313730..314089 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 314089 7781584 VCM66_A0295 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002811929.1 313730 D 579112 CDS YP_002811930.1 227811920 7781585 314221..314709 1 NC_012580.1 OsmC-like protein 314709 7781585 VCM66_A0296 Vibrio cholerae M66-2 OsmC-like protein YP_002811930.1 314221 D 579112 CDS YP_002811931.1 227811921 7781586 314828..314989 1 NC_012580.1 hypothetical protein 314989 7781586 VCM66_A0297 Vibrio cholerae M66-2 hypothetical protein YP_002811931.1 314828 D 579112 CDS YP_002811932.1 227811922 7781587 315406..315654 1 NC_012580.1 hypothetical protein 315654 7781587 VCM66_A0300 Vibrio cholerae M66-2 hypothetical protein YP_002811932.1 315406 D 579112 CDS YP_002811933.1 227811923 7781588 315851..316969 1 NC_012580.1 hypothetical protein 316969 7781588 VCM66_A0301 Vibrio cholerae M66-2 hypothetical protein YP_002811933.1 315851 D 579112 CDS YP_002811934.1 227811924 7781589 317111..317587 1 NC_012580.1 GCN5-related N-acetyltransferase 317587 7781589 VCM66_A0302 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811934.1 317111 D 579112 CDS YP_002811935.1 227811925 7781590 complement(317764..317898) 1 NC_012580.1 hypothetical protein 317898 7781590 VCM66_A0303 Vibrio cholerae M66-2 hypothetical protein YP_002811935.1 317764 R 579112 CDS YP_002811936.1 227811926 7781591 317883..318062 1 NC_012580.1 hypothetical protein 318062 7781591 VCM66_A0304 Vibrio cholerae M66-2 hypothetical protein YP_002811936.1 317883 D 579112 CDS YP_002811937.1 227811927 7781592 318250..318771 1 NC_012580.1 GCN5-related N-acetyltransferase 318771 7781592 VCM66_A0305 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811937.1 318250 D 579112 CDS YP_002811938.1 227811928 7781593 318907..319422 1 NC_012580.1 Lipocalin-like protein 319422 7781593 VCM66_A0306 Vibrio cholerae M66-2 Lipocalin-like protein YP_002811938.1 318907 D 579112 CDS YP_002811939.1 227811929 7781594 319559..320101 1 NC_012580.1 hypothetical protein 320101 7781594 VCM66_A0307 Vibrio cholerae M66-2 hypothetical protein YP_002811939.1 319559 D 579112 CDS YP_002811940.1 227811930 7781595 320220..320381 1 NC_012580.1 hypothetical protein 320381 7781595 VCM66_A0308 Vibrio cholerae M66-2 hypothetical protein YP_002811940.1 320220 D 579112 CDS YP_002811941.1 227811931 7781596 320893..321045 1 NC_012580.1 hypothetical protein 321045 7781596 VCM66_A0311 Vibrio cholerae M66-2 hypothetical protein YP_002811941.1 320893 D 579112 CDS YP_002811942.1 227811932 7781597 complement(321245..321523) 1 NC_012580.1 plasmid stabilization system protein 321523 7781597 VCM66_A0312 Vibrio cholerae M66-2 plasmid stabilization system protein YP_002811942.1 321245 R 579112 CDS YP_002811943.1 227811933 7781598 complement(321520..321840) 1 NC_012580.1 relB protein 321840 7781598 VCM66_A0313 Vibrio cholerae M66-2 relB protein YP_002811943.1 321520 R 579112 CDS YP_002811944.1 227811934 7781599 complement(321980..322279) 1 NC_012580.1 putative plasmid stabilization element ParE 322279 7781599 VCM66_A0314 Vibrio cholerae M66-2 putative plasmid stabilization element ParE YP_002811944.1 321980 R 579112 CDS YP_002811945.1 227811935 7781600 complement(322266..322589) 1 NC_012580.1 hypothetical protein 322589 7781600 VCM66_A0315 Vibrio cholerae M66-2 hypothetical protein YP_002811945.1 322266 R 579112 CDS YP_002811946.1 227811936 7781601 324264..324692 1 NC_012580.1 GCN5-related N-acetyltransferase 324692 7781601 VCM66_A0318 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811946.1 324264 D 579112 CDS YP_002811947.1 227811937 7781602 325280..325762 1 NC_012580.1 GCN5-related N-acetyltransferase 325762 7781602 VCM66_A0319 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811947.1 325280 D 579112 CDS YP_002811948.1 227811938 7781603 326564..326839 1 NC_012580.1 hypothetical protein 326839 7781603 VCM66_A0320 Vibrio cholerae M66-2 hypothetical protein YP_002811948.1 326564 D 579112 CDS YP_002811949.1 227811939 7781604 326833..327354 1 NC_012580.1 hypothetical protein 327354 7781604 VCM66_A0321 Vibrio cholerae M66-2 hypothetical protein YP_002811949.1 326833 D 579112 CDS YP_002811950.1 227811940 7781605 327493..328329 1 NC_012580.1 hypothetical protein 328329 7781605 VCM66_A0322 Vibrio cholerae M66-2 hypothetical protein YP_002811950.1 327493 D 579112 CDS YP_002811951.1 227811941 7781606 328494..329132 1 NC_012580.1 Metal-dependent phosphohydrolase with HD region, subdomain 329132 7781606 VCM66_A0323 Vibrio cholerae M66-2 Metal-dependent phosphohydrolase with HD region, subdomain YP_002811951.1 328494 D 579112 CDS YP_002811952.1 227811942 7781607 329403..329624 1 NC_012580.1 hypothetical protein 329624 7781607 VCM66_A0324 Vibrio cholerae M66-2 hypothetical protein YP_002811952.1 329403 D 579112 CDS YP_002811953.1 227811943 7781608 329944..330264 1 NC_012580.1 hypothetical protein 330264 7781608 VCM66_A0325 Vibrio cholerae M66-2 hypothetical protein YP_002811953.1 329944 D 579112 CDS YP_002811954.1 227811944 7781609 330261..330794 1 NC_012580.1 GCN5-related N-acetyltransferase 330794 7781609 VCM66_A0326 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811954.1 330261 D 579112 CDS YP_002811955.1 227811945 7781610 330987..331310 1 NC_012580.1 hypothetical protein 331310 7781610 VCM66_A0327 Vibrio cholerae M66-2 hypothetical protein YP_002811955.1 330987 D 579112 CDS YP_002811956.1 227811946 7781611 331562..331687 1 NC_012580.1 hypothetical protein 331687 7781611 VCM66_A0328 Vibrio cholerae M66-2 hypothetical protein YP_002811956.1 331562 D 579112 CDS YP_002811957.1 227811947 7781612 331711..331935 1 NC_012580.1 hypothetical protein 331935 7781612 VCM66_A0328a Vibrio cholerae M66-2 hypothetical protein YP_002811957.1 331711 D 579112 CDS YP_002811958.1 227811948 7781613 complement(332186..332458) 1 NC_012580.1 hypothetical protein 332458 7781613 VCM66_A0329 Vibrio cholerae M66-2 hypothetical protein YP_002811958.1 332186 R 579112 CDS YP_002811959.1 227811949 7781614 332628..333062 1 NC_012580.1 hypothetical protein 333062 7781614 VCM66_A0330 Vibrio cholerae M66-2 hypothetical protein YP_002811959.1 332628 D 579112 CDS YP_002811960.1 227811950 7781615 333195..333710 1 NC_012580.1 hypothetical protein 333710 7781615 VCM66_A0331 Vibrio cholerae M66-2 hypothetical protein YP_002811960.1 333195 D 579112 CDS YP_002811961.1 227811951 7781616 333851..334288 1 NC_012580.1 NUDIX hydrolase 334288 7781616 VCM66_A0332 Vibrio cholerae M66-2 NUDIX hydrolase YP_002811961.1 333851 D 579112 CDS YP_002811962.1 227811952 7781617 334449..334796 1 NC_012580.1 hypothetical protein 334796 7781617 VCM66_A0333 Vibrio cholerae M66-2 hypothetical protein YP_002811962.1 334449 D 579112 CDS YP_002811963.1 227811953 7781618 334937..336502 1 NC_012580.1 hypothetical protein 336502 7781618 VCM66_A0334 Vibrio cholerae M66-2 hypothetical protein YP_002811963.1 334937 D 579112 CDS YP_002811964.1 227811954 7781619 336638..337198 1 NC_012580.1 hypothetical protein 337198 7781619 VCM66_A0335 Vibrio cholerae M66-2 hypothetical protein YP_002811964.1 336638 D 579112 CDS YP_002811965.1 227811955 7781620 337348..338022 1 NC_012580.1 hypothetical protein 338022 7781620 VCM66_A0336 Vibrio cholerae M66-2 hypothetical protein YP_002811965.1 337348 D 579112 CDS YP_002811966.1 227811956 7781621 338253..338501 1 NC_012580.1 hypothetical protein 338501 7781621 VCM66_A0337 Vibrio cholerae M66-2 hypothetical protein YP_002811966.1 338253 D 579112 CDS YP_002811967.1 227811957 7781622 338716..339468 1 NC_012580.1 Short-chain dehydrogenase/reductase SDR 339468 7781622 VCM66_A0338 Vibrio cholerae M66-2 Short-chain dehydrogenase/reductase SDR YP_002811967.1 338716 D 579112 CDS YP_002811968.1 227811958 7781623 339770..339952 1 NC_012580.1 hypothetical protein 339952 7781623 VCM66_A0339 Vibrio cholerae M66-2 hypothetical protein YP_002811968.1 339770 D 579112 CDS YP_002811969.1 227811959 7781624 340130..340534 1 NC_012580.1 hypothetical protein 340534 7781624 VCM66_A0340 Vibrio cholerae M66-2 hypothetical protein YP_002811969.1 340130 D 579112 CDS YP_002811970.1 227811960 7781625 340830..341012 1 NC_012580.1 hypothetical protein 341012 7781625 VCM66_A0341 Vibrio cholerae M66-2 hypothetical protein YP_002811970.1 340830 D 579112 CDS YP_002811971.1 227811961 7781626 complement(341250..341366) 1 NC_012580.1 hypothetical protein 341366 7781626 VCM66_A0342 Vibrio cholerae M66-2 hypothetical protein YP_002811971.1 341250 R 579112 CDS YP_002811972.1 227811962 7781627 341366..341548 1 NC_012580.1 hypothetical protein 341548 7781627 VCM66_A0343 Vibrio cholerae M66-2 hypothetical protein YP_002811972.1 341366 D 579112 CDS YP_002811973.1 227811963 7781628 341743..342420 1 NC_012580.1 HNH endonuclease 342420 7781628 VCM66_A0344 Vibrio cholerae M66-2 HNH endonuclease YP_002811973.1 341743 D 579112 CDS YP_002811974.1 227811964 7781629 342582..343790 1 NC_012580.1 deoxyguanosinetriphosphate triphosphohydrolase-related protein 343790 7781629 VCM66_A0345 Vibrio cholerae M66-2 deoxyguanosinetriphosphate triphosphohydrolase-related protein YP_002811974.1 342582 D 579112 CDS YP_002811975.1 227811965 7781630 343952..344656 1 NC_012580.1 HNH endonuclease 344656 7781630 VCM66_A0346 Vibrio cholerae M66-2 HNH endonuclease YP_002811975.1 343952 D 579112 CDS YP_002811976.1 227811966 7781631 344787..345152 1 NC_012580.1 hypothetical protein 345152 7781631 VCM66_A0347 Vibrio cholerae M66-2 hypothetical protein YP_002811976.1 344787 D 579112 CDS YP_002811977.1 227811967 7781632 complement(345306..345641) 1 NC_012580.1 Plasmid stabilization system protein 345641 7781632 VCM66_A0348 Vibrio cholerae M66-2 Plasmid stabilization system protein YP_002811977.1 345306 R 579112 CDS YP_002811978.1 227811968 7781633 complement(345642..345884) 1 NC_012580.1 Prevent-host-death protein 345884 7781633 VCM66_A0349 Vibrio cholerae M66-2 Prevent-host-death protein YP_002811978.1 345642 R 579112 CDS YP_002811979.1 227811969 7781634 346128..346514 1 NC_012580.1 NUDIX hydrolase 346514 7781634 VCM66_A0350 Vibrio cholerae M66-2 NUDIX hydrolase YP_002811979.1 346128 D 579112 CDS YP_002811980.1 227811970 7781635 346633..346914 1 NC_012580.1 hypothetical protein 346914 7781635 VCM66_A0351 Vibrio cholerae M66-2 hypothetical protein YP_002811980.1 346633 D 579112 CDS YP_002811981.1 227811971 7781636 complement(346890..347021) 1 NC_012580.1 hypothetical protein 347021 7781636 VCM66_A0352 Vibrio cholerae M66-2 hypothetical protein YP_002811981.1 346890 R 579112 CDS YP_002811982.1 227811972 7781637 347172..347708 1 NC_012580.1 GCN5-related N-acetyltransferase 347708 7781637 VCM66_A0355 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811982.1 347172 D 579112 CDS YP_002811983.1 227811973 7781638 347845..348360 1 NC_012580.1 Lipocalin-like protein 348360 7781638 VCM66_A0356 Vibrio cholerae M66-2 Lipocalin-like protein YP_002811983.1 347845 D 579112 CDS YP_002811984.1 227811974 7781639 complement(348510..349007) 1 NC_012580.1 GCN5-related N-acetyltransferase 349007 7781639 VCM66_A0357 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002811984.1 348510 R 579112 CDS YP_002811985.1 227811975 7781640 complement(349004..349276) 1 NC_012580.1 hypothetical protein 349276 7781640 VCM66_A0358 Vibrio cholerae M66-2 hypothetical protein YP_002811985.1 349004 R 579112 CDS YP_002811986.1 227811976 7781641 complement(349502..349666) 1 NC_012580.1 hypothetical protein 349666 7781641 VCM66_A0359 Vibrio cholerae M66-2 hypothetical protein YP_002811986.1 349502 R 579112 CDS YP_002811987.1 227811977 7781642 complement(349781..349891) 1 NC_012580.1 hypothetical protein 349891 7781642 VCM66_A0360 Vibrio cholerae M66-2 hypothetical protein YP_002811987.1 349781 R 579112 CDS YP_002811988.1 227811978 7781643 350038..350490 1 NC_012580.1 hypothetical protein 350490 7781643 VCM66_A0361 Vibrio cholerae M66-2 hypothetical protein YP_002811988.1 350038 D 579112 CDS YP_002811989.1 227811979 7781644 complement(350638..350934) 1 NC_012580.1 plasmid stabilization system protein 350934 7781644 VCM66_A0362 Vibrio cholerae M66-2 plasmid stabilization system protein YP_002811989.1 350638 R 579112 CDS YP_002811990.1 227811980 7781645 complement(350900..351178) 1 NC_012580.1 DNA-damage-inducible protein J 351178 7781645 VCM66_A0363 Vibrio cholerae M66-2 DNA-damage-inducible protein J YP_002811990.1 350900 R 579112 CDS YP_002811991.1 227811981 7781646 351428..351685 1 NC_012580.1 antitoxin of toxin-antitoxin stability system 351685 7781646 VCM66_A0364 Vibrio cholerae M66-2 antitoxin of toxin-antitoxin stability system YP_002811991.1 351428 D 579112 CDS YP_002811992.1 227811982 7781647 351673..351975 1 NC_012580.1 plasmid stabilization system protein 351975 7781647 VCM66_A0365 Vibrio cholerae M66-2 plasmid stabilization system protein YP_002811992.1 351673 D 579112 CDS YP_002811993.1 227811983 7781648 352115..352240 1 NC_012580.1 hypothetical protein 352240 7781648 VCM66_A0365a Vibrio cholerae M66-2 hypothetical protein YP_002811993.1 352115 D 579112 CDS YP_002811994.1 227811984 7781649 352264..352488 1 NC_012580.1 hypothetical protein 352488 7781649 VCM66_A0366 Vibrio cholerae M66-2 hypothetical protein YP_002811994.1 352264 D 579112 CDS YP_002811995.1 227811985 7781650 complement(353273..353545) 1 NC_012580.1 hypothetical protein 353545 7781650 VCM66_A0368 Vibrio cholerae M66-2 hypothetical protein YP_002811995.1 353273 R 579112 CDS YP_002811996.1 227811986 7781651 353710..354714 1 NC_012580.1 microcin immunity protein MccF 354714 7781651 VCM66_A0369 Vibrio cholerae M66-2 microcin immunity protein MccF YP_002811996.1 353710 D 579112 CDS YP_002811997.1 227811987 7781652 354906..355163 1 NC_012580.1 hypothetical protein 355163 7781652 VCM66_A0370 Vibrio cholerae M66-2 hypothetical protein YP_002811997.1 354906 D 579112 CDS YP_002811998.1 227811988 7781653 355870..356223 1 NC_012580.1 putative killer protein 356223 7781653 VCM66_A0371 Vibrio cholerae M66-2 putative killer protein YP_002811998.1 355870 D 579112 CDS YP_002811999.1 227811989 7781654 356234..356551 1 NC_012580.1 putative antidote protein 356551 7781654 VCM66_A0372 Vibrio cholerae M66-2 putative antidote protein YP_002811999.1 356234 D 579112 CDS YP_002812000.1 227811990 7781655 356731..357054 1 NC_012580.1 hypothetical protein 357054 7781655 VCM66_A0373 Vibrio cholerae M66-2 hypothetical protein YP_002812000.1 356731 D 579112 CDS YP_002812001.1 227811991 7781656 complement(357097..357198) 1 NC_012580.1 hypothetical protein 357198 7781656 VCM66_A0374 Vibrio cholerae M66-2 hypothetical protein YP_002812001.1 357097 R 579112 CDS YP_002812002.1 227811992 7781657 357369..357512 1 NC_012580.1 hypothetical protein 357512 7781657 VCM66_A0375 Vibrio cholerae M66-2 hypothetical protein YP_002812002.1 357369 D 579112 CDS YP_002812003.1 227811993 7781658 357791..358189 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 358189 7781658 VCM66_A0376 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002812003.1 357791 D 579112 CDS YP_002812004.1 227811994 7781659 358384..358635 1 NC_012580.1 hypothetical protein 358635 7781659 VCM66_A0377 Vibrio cholerae M66-2 hypothetical protein YP_002812004.1 358384 D 579112 CDS YP_002812005.1 227811995 7781660 358809..359162 1 NC_012580.1 hypothetical protein 359162 7781660 VCM66_A0378 Vibrio cholerae M66-2 hypothetical protein YP_002812005.1 358809 D 579112 CDS YP_002812006.1 227811996 7781661 359374..359616 1 NC_012580.1 hypothetical protein 359616 7781661 VCM66_A0379 Vibrio cholerae M66-2 hypothetical protein YP_002812006.1 359374 D 579112 CDS YP_002812007.1 227811997 7781662 359823..360146 1 NC_012580.1 hypothetical protein 360146 7781662 VCM66_A0380 Vibrio cholerae M66-2 hypothetical protein YP_002812007.1 359823 D 579112 CDS YP_002812008.1 227811998 7781663 360947..361435 1 NC_012580.1 OsmC-like protein 361435 7781663 VCM66_A0381 Vibrio cholerae M66-2 OsmC-like protein YP_002812008.1 360947 D 579112 CDS YP_002812009.1 227811999 7781664 361620..362225 1 NC_012580.1 hypothetical protein 362225 7781664 VCM66_A0382 Vibrio cholerae M66-2 hypothetical protein YP_002812009.1 361620 D 579112 CDS YP_002812010.1 227812000 7781665 362410..362676 1 NC_012580.1 hypothetical protein 362676 7781665 VCM66_A0383 Vibrio cholerae M66-2 hypothetical protein YP_002812010.1 362410 D 579112 CDS YP_002812011.1 227812001 7781666 362663..362908 1 NC_012580.1 hypothetical protein 362908 7781666 VCM66_A0384 Vibrio cholerae M66-2 hypothetical protein YP_002812011.1 362663 D 579112 CDS YP_002812012.1 227812002 7781667 362992..363798 1 NC_012580.1 hypothetical protein 363798 7781667 VCM66_A0385 Vibrio cholerae M66-2 hypothetical protein YP_002812012.1 362992 D 579112 CDS YP_002812013.1 227812003 7781668 complement(364007..364108) 1 NC_012580.1 hypothetical protein 364108 7781668 VCM66_A0386 Vibrio cholerae M66-2 hypothetical protein YP_002812013.1 364007 R 579112 CDS YP_002812014.1 227812004 7781669 364090..364272 1 NC_012580.1 hypothetical protein 364272 7781669 VCM66_A0387 Vibrio cholerae M66-2 hypothetical protein YP_002812014.1 364090 D 579112 CDS YP_002812015.1 227812005 7781670 364469..364894 1 NC_012580.1 GCN5-related N-acetyltransferase 364894 7781670 VCM66_A0388 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812015.1 364469 D 579112 CDS YP_002812016.1 227812006 7781671 365034..365624 1 NC_012580.1 hypothetical protein 365624 7781671 VCM66_A0389 Vibrio cholerae M66-2 hypothetical protein YP_002812016.1 365034 D 579112 CDS YP_002812017.1 227812007 7781672 365778..366137 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 366137 7781672 VCM66_A0390 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002812017.1 365778 D 579112 CDS YP_002812018.1 227812008 7781673 366284..366937 1 NC_012580.1 hypothetical protein 366937 7781673 VCM66_A0391 Vibrio cholerae M66-2 hypothetical protein YP_002812018.1 366284 D 579112 CDS YP_002812019.1 227812009 7781675 367746..368042 1 NC_012580.1 Stress responsive alpha-beta barrel 368042 7781675 VCM66_A0393 Vibrio cholerae M66-2 Stress responsive alpha-beta barrel YP_002812019.1 367746 D 579112 CDS YP_002812020.1 227812010 7781676 368196..368588 1 NC_012580.1 hypothetical protein 368588 7781676 VCM66_A0394 Vibrio cholerae M66-2 hypothetical protein YP_002812020.1 368196 D 579112 CDS YP_002812021.1 227812011 7781678 complement(369634..370506) 1 NC_012580.1 ISVch4 transposase, OrfA 370506 7781678 VCM66_A0396 Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002812021.1 369634 R 579112 CDS YP_002812022.1 227812012 7781679 complement(370503..370847) 1 NC_012580.1 ISVch4 transposase, OrfB 370847 7781679 VCM66_A0397 Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002812022.1 370503 R 579112 CDS YP_002812023.1 227812013 7781681 371199..372236 1 NC_012580.1 hypothetical protein 372236 7781681 VCM66_A0399 Vibrio cholerae M66-2 hypothetical protein YP_002812023.1 371199 D 579112 CDS YP_002812024.1 227812014 7781682 372908..373261 1 NC_012580.1 putative killer protein 373261 7781682 VCM66_A0400 Vibrio cholerae M66-2 putative killer protein YP_002812024.1 372908 D 579112 CDS YP_002812025.1 227812015 7781683 373272..373589 1 NC_012580.1 putative antidote protein 373589 7781683 VCM66_A0401 Vibrio cholerae M66-2 putative antidote protein YP_002812025.1 373272 D 579112 CDS YP_002812026.1 227812016 7781684 373724..374200 1 NC_012580.1 GCN5-related N-acetyltransferase 374200 7781684 VCM66_A0402 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812026.1 373724 D 579112 CDS YP_002812027.1 227812017 7781685 374337..374852 1 NC_012580.1 Lipocalin-like protein 374852 7781685 VCM66_A0403 Vibrio cholerae M66-2 Lipocalin-like protein YP_002812027.1 374337 D 579112 CDS YP_002812028.1 227812018 7781686 complement(374988..375278) 1 NC_012580.1 relE protein 375278 7781686 VCM66_A0404 Vibrio cholerae M66-2 relE protein YP_002812028.1 374988 R 579112 CDS YP_002812029.1 227812019 7781687 complement(375268..375516) 1 NC_012580.1 antitoxin of toxin-antitoxin stability system, StbD family 375516 7781687 VCM66_A0405 Vibrio cholerae M66-2 antitoxin of toxin-antitoxin stability system, StbD family YP_002812029.1 375268 R 579112 CDS YP_002812030.1 227812020 7781688 375781..375972 1 NC_012580.1 hypothetical protein 375972 7781688 VCM66_A0406 Vibrio cholerae M66-2 hypothetical protein YP_002812030.1 375781 D 579112 CDS YP_002812031.1 227812021 7781689 376048..376740 1 NC_012580.1 DNA methylase N-4/N-6 376740 7781689 VCM66_A0407 Vibrio cholerae M66-2 DNA methylase N-4/N-6 YP_002812031.1 376048 D 579112 CDS YP_002812032.1 227812022 7781690 377012..377437 1 NC_012580.1 hypothetical protein 377437 7781690 VCM66_A0408 Vibrio cholerae M66-2 hypothetical protein YP_002812032.1 377012 D 579112 CDS YP_002812033.1 227812023 7781691 377615..378040 1 NC_012580.1 hypothetical protein 378040 7781691 VCM66_A0409 Vibrio cholerae M66-2 hypothetical protein YP_002812033.1 377615 D 579112 CDS YP_002812034.1 227812024 7781692 378191..378721 1 NC_012580.1 hypothetical protein 378721 7781692 VCM66_A0410 Vibrio cholerae M66-2 hypothetical protein YP_002812034.1 378191 D 579112 CDS YP_002812035.1 227812025 7781693 378859..379359 1 NC_012580.1 hypothetical protein 379359 7781693 VCM66_A0411 Vibrio cholerae M66-2 hypothetical protein YP_002812035.1 378859 D 579112 CDS YP_002812036.1 227812026 7781694 379485..379913 1 NC_012580.1 hypothetical protein 379913 7781694 VCM66_A0412 Vibrio cholerae M66-2 hypothetical protein YP_002812036.1 379485 D 579112 CDS YP_002812037.1 227812027 7781695 complement(380013..380477) 1 NC_012580.1 hypothetical protein 380477 7781695 VCM66_A0413 Vibrio cholerae M66-2 hypothetical protein YP_002812037.1 380013 R 579112 CDS YP_002812038.1 227812028 7781696 complement(380860..381846) 1 NC_012580.1 periplasmic sulfate binding protein SBP 381846 7781696 VCM66_A0414 Vibrio cholerae M66-2 periplasmic sulfate binding protein SBP YP_002812038.1 380860 R 579112 CDS YP_002812039.1 227812029 7781697 382079..382675 1 NC_012580.1 ThiJ/PfpI 382675 7781697 VCM66_A0415 Vibrio cholerae M66-2 ThiJ/PfpI YP_002812039.1 382079 D 579112 CDS YP_002812040.1 227812030 7781698 complement(382966..383100) 1 NC_012580.1 hypothetical protein 383100 7781698 VCM66_A0416 Vibrio cholerae M66-2 hypothetical protein YP_002812040.1 382966 R 579112 CDS YP_002812041.1 227812031 7781699 383472..384086 1 NC_012580.1 hypothetical protein 384086 7781699 VCM66_A0417 Vibrio cholerae M66-2 hypothetical protein YP_002812041.1 383472 D 579112 CDS YP_002812042.1 227812032 7781700 384233..385090 1 NC_012580.1 hypothetical protein 385090 7781700 VCM66_A0418 Vibrio cholerae M66-2 hypothetical protein YP_002812042.1 384233 D 579112 CDS YP_002812043.1 227812033 7781701 385237..385797 1 NC_012580.1 hypothetical protein 385797 7781701 VCM66_A0419 Vibrio cholerae M66-2 hypothetical protein YP_002812043.1 385237 D 579112 CDS YP_002812044.1 227812034 7781702 385940..386287 1 NC_012580.1 hypothetical protein 386287 7781702 VCM66_A0420 Vibrio cholerae M66-2 hypothetical protein YP_002812044.1 385940 D 579112 CDS YP_002812045.1 227812035 7781703 386418..386543 1 NC_012580.1 hypothetical protein 386543 7781703 VCM66_A0421 Vibrio cholerae M66-2 hypothetical protein YP_002812045.1 386418 D 579112 CDS YP_002812046.1 227812036 7781704 complement(386679..386783) 1 NC_012580.1 hypothetical protein 386783 7781704 VCM66_A0422 Vibrio cholerae M66-2 hypothetical protein YP_002812046.1 386679 R 579112 CDS YP_002812047.1 227812037 7781705 388056..388454 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 388454 7781705 VCM66_A0423 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002812047.1 388056 D 579112 CDS YP_002812048.1 227812038 7781706 388656..388898 1 NC_012580.1 hypothetical protein 388898 7781706 VCM66_A0424 Vibrio cholerae M66-2 hypothetical protein YP_002812048.1 388656 D 579112 CDS YP_002812049.1 227812039 7781707 389042..389446 1 NC_012580.1 hypothetical protein 389446 7781707 VCM66_A0425 Vibrio cholerae M66-2 hypothetical protein YP_002812049.1 389042 D 579112 CDS YP_002812050.1 227812040 7781708 389566..389847 1 NC_012580.1 hypothetical protein 389847 7781708 VCM66_A0426 Vibrio cholerae M66-2 hypothetical protein YP_002812050.1 389566 D 579112 CDS YP_002812051.1 227812041 7781709 complement(389823..389954) 1 NC_012580.1 hypothetical protein 389954 7781709 VCM66_A0427 Vibrio cholerae M66-2 hypothetical protein YP_002812051.1 389823 R 579112 CDS YP_002812052.1 227812042 7781711 complement(390332..390463) 1 NC_012580.1 hypothetical protein 390463 7781711 VCM66_A0429 Vibrio cholerae M66-2 hypothetical protein YP_002812052.1 390332 R 579112 CDS YP_002812053.1 227812043 7781712 390643..390975 1 NC_012580.1 hypothetical protein 390975 7781712 VCM66_A0430 Vibrio cholerae M66-2 hypothetical protein YP_002812053.1 390643 D 579112 CDS YP_002812054.1 227812044 7781713 390962..391276 1 NC_012580.1 virulence gene repressor RsaL 391276 7781713 VCM66_A0431 Vibrio cholerae M66-2 virulence gene repressor RsaL YP_002812054.1 390962 D 579112 CDS YP_002812055.1 227812045 7781714 391413..391847 1 NC_012580.1 GCN5-related N-acetyltransferase 391847 7781714 VCM66_A0432 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812055.1 391413 D 579112 CDS YP_002812056.1 227812046 7781715 392015..392170 1 NC_012580.1 hypothetical protein 392170 7781715 VCM66_A0433 Vibrio cholerae M66-2 hypothetical protein YP_002812056.1 392015 D 579112 CDS YP_002812057.1 227812047 7781716 complement(392295..393275) 1 NC_012580.1 ISVch5 transposase 393275 7781716 VCM66_A0434 Vibrio cholerae M66-2 ISVch5 transposase YP_002812057.1 392295 R 579112 CDS YP_002812058.1 227812048 7781717 393298..393615 1 NC_012580.1 hypothetical protein 393615 7781717 VCM66_A0435 Vibrio cholerae M66-2 hypothetical protein YP_002812058.1 393298 D 579112 CDS YP_002812059.1 227812049 7781718 393786..394478 1 NC_012580.1 GCN5-related N-acetyltransferase 394478 7781718 VCM66_A0436 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812059.1 393786 D 579112 CDS YP_002812060.1 227812050 7781719 394478..394879 1 NC_012580.1 doc protein 394879 7781719 VCM66_A0437 Vibrio cholerae M66-2 doc protein YP_002812060.1 394478 D 579112 CDS YP_002812061.1 227812051 7781720 395067..395480 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 395480 7781720 VCM66_A0438 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002812061.1 395067 D 579112 CDS YP_002812062.1 227812052 7781721 395673..395945 1 NC_012580.1 antitoxin of toxin-antitoxin stability system 395945 7781721 VCM66_A0439 Vibrio cholerae M66-2 antitoxin of toxin-antitoxin stability system YP_002812062.1 395673 D 579112 CDS YP_002812063.1 227812053 7781722 395932..396222 1 NC_012580.1 Cytotoxic translational repressor of toxin-antitoxin stability system 396222 7781722 VCM66_A0440 Vibrio cholerae M66-2 Cytotoxic translational repressor of toxin-antitoxin stability system YP_002812063.1 395932 D 579112 CDS YP_002812064.1 227812054 7781723 396350..396805 1 NC_012580.1 GCN5-related N-acetyltransferase 396805 7781723 VCM66_A0441 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812064.1 396350 D 579112 CDS YP_002812065.1 227812055 7781724 397127..397279 1 NC_012580.1 hypothetical protein 397279 7781724 VCM66_A0442 Vibrio cholerae M66-2 hypothetical protein YP_002812065.1 397127 D 579112 CDS YP_002812066.1 227812056 7781725 complement(397481..397978) 1 NC_012580.1 GCN5-related N-acetyltransferase 397978 7781725 VCM66_A0443 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812066.1 397481 R 579112 CDS YP_002812067.1 227812057 7781726 complement(397975..398247) 1 NC_012580.1 hypothetical protein 398247 7781726 VCM66_A0444 Vibrio cholerae M66-2 hypothetical protein YP_002812067.1 397975 R 579112 CDS YP_002812068.1 227812058 7781727 398478..399146 1 NC_012580.1 hypothetical protein 399146 7781727 VCM66_A0445 Vibrio cholerae M66-2 hypothetical protein YP_002812068.1 398478 D 579112 CDS YP_002812069.1 227812059 7781728 399298..399585 1 NC_012580.1 hypothetical protein 399585 7781728 VCM66_A0446 Vibrio cholerae M66-2 hypothetical protein YP_002812069.1 399298 D 579112 CDS YP_002812070.1 227812060 7781729 399726..400097 1 NC_012580.1 mazG-related protein 400097 7781729 VCM66_A0447 Vibrio cholerae M66-2 mazG-related protein YP_002812070.1 399726 D 579112 CDS YP_002812071.1 227812061 7781730 400269..400589 1 NC_012580.1 hypothetical protein 400589 7781730 VCM66_A0448 Vibrio cholerae M66-2 hypothetical protein YP_002812071.1 400269 D 579112 CDS YP_002812072.1 227812062 7781731 400586..401119 1 NC_012580.1 GCN5-related N-acetyltransferase 401119 7781731 VCM66_A0449 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812072.1 400586 D 579112 CDS YP_002812073.1 227812063 7781732 401321..401578 1 NC_012580.1 antitoxin of toxin-antitoxin stability system 401578 7781732 VCM66_A0450 Vibrio cholerae M66-2 antitoxin of toxin-antitoxin stability system YP_002812073.1 401321 D 579112 CDS YP_002812074.1 227812064 7781733 401566..401868 1 NC_012580.1 Plasmid stabilization system protein 401868 7781733 VCM66_A0451 Vibrio cholerae M66-2 Plasmid stabilization system protein YP_002812074.1 401566 D 579112 CDS YP_002812075.1 227812065 7781735 402350..402787 1 NC_012580.1 IS1004 transposase 402787 7781735 VCM66_A0453 Vibrio cholerae M66-2 IS1004 transposase YP_002812075.1 402350 D 579112 CDS YP_002812076.1 227812066 7781737 403244..404116 1 NC_012580.1 hypothetical protein 404116 7781737 VCM66_A0455 Vibrio cholerae M66-2 hypothetical protein YP_002812076.1 403244 D 579112 CDS YP_002812077.1 227812067 7781738 404248..404865 1 NC_012580.1 putative glutathione S-transferase 404865 7781738 VCM66_A0456 Vibrio cholerae M66-2 putative glutathione S-transferase YP_002812077.1 404248 D 579112 CDS YP_002812078.1 227812068 7781739 405051..405326 1 NC_012580.1 hypothetical protein 405326 7781739 VCM66_A0457 Vibrio cholerae M66-2 hypothetical protein YP_002812078.1 405051 D 579112 CDS YP_002812079.1 227812069 7781740 405320..405841 1 NC_012580.1 hypothetical protein 405841 7781740 VCM66_A0458 Vibrio cholerae M66-2 hypothetical protein YP_002812079.1 405320 D 579112 CDS YP_002812080.1 227812070 7781741 complement(405973..406137) 1 NC_012580.1 hypothetical protein 406137 7781741 VCM66_A0459 Vibrio cholerae M66-2 hypothetical protein YP_002812080.1 405973 R 579112 CDS YP_002812081.1 227812071 7781742 complement(406134..406235) 1 NC_012580.1 hypothetical protein 406235 7781742 VCM66_A0460 Vibrio cholerae M66-2 hypothetical protein YP_002812081.1 406134 R 579112 CDS YP_002812082.1 227812072 7781743 406516..406911 1 NC_012580.1 hypothetical protein 406911 7781743 VCM66_A0461 Vibrio cholerae M66-2 hypothetical protein YP_002812082.1 406516 D 579112 CDS YP_002812083.1 227812073 7781744 complement(407050..407328) 1 NC_012580.1 plasmid stabilization system protein 407328 7781744 VCM66_A0462 Vibrio cholerae M66-2 plasmid stabilization system protein YP_002812083.1 407050 R 579112 CDS YP_002812084.1 227812074 7781745 complement(407325..407645) 1 NC_012580.1 relB protein 407645 7781745 VCM66_A0463 Vibrio cholerae M66-2 relB protein YP_002812084.1 407325 R 579112 CDS YP_002812085.1 227812075 7781746 407797..408318 1 NC_012580.1 GCN5-related N-acetyltransferase 408318 7781746 VCM66_A0464 Vibrio cholerae M66-2 GCN5-related N-acetyltransferase YP_002812085.1 407797 D 579112 CDS YP_002812086.1 227812076 7781747 408502..408915 1 NC_012580.1 Glyoxalase/bleomycin resistance protein 408915 7781747 VCM66_A0465 Vibrio cholerae M66-2 Glyoxalase/bleomycin resistance protein YP_002812086.1 408502 D 579112 CDS YP_002812087.1 227812077 7781748 409434..409778 1 NC_012580.1 ISVch4 transposase, OrfA 409778 orfA 7781748 orfA Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002812087.1 409434 D 579112 CDS YP_002812088.1 227812078 7781749 409775..410647 1 NC_012580.1 ISVch4 transposase, OrfB 410647 orfB 7781749 orfB Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002812088.1 409775 D 579112 CDS YP_002812089.1 227812079 7781750 complement(410685..410804) 1 NC_012580.1 hypothetical protein 410804 7781750 VCM66_A0468 Vibrio cholerae M66-2 hypothetical protein YP_002812089.1 410685 R 579112 CDS YP_002812090.1 227812080 7781751 410937..413843 1 NC_012580.1 hypothetical protein 413843 7781751 VCM66_A0469 Vibrio cholerae M66-2 hypothetical protein YP_002812090.1 410937 D 579112 CDS YP_002812091.1 227812081 7781752 414306..416426 1 NC_012580.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 416426 nrdD 7781752 nrdD Vibrio cholerae M66-2 anaerobic ribonucleoside triphosphate reductase YP_002812091.1 414306 D 579112 CDS YP_002812092.1 227812082 7781753 416431..416898 1 NC_012580.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 416898 nrdG 7781753 nrdG Vibrio cholerae M66-2 anaerobic ribonucleotide reductase-activating protein YP_002812092.1 416431 D 579112 CDS YP_002812093.1 227812083 7781754 416987..418201 1 NC_012580.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 418201 7781754 VCM66_A0472 Vibrio cholerae M66-2 aromatic amino acid aminotransferase YP_002812093.1 416987 D 579112 CDS YP_002812094.1 227812084 7781755 418259..418942 1 NC_012580.1 Ribosomal protein S6 modification protein 418942 7781755 VCM66_A0473 Vibrio cholerae M66-2 Ribosomal protein S6 modification protein YP_002812094.1 418259 D 579112 CDS YP_002812095.1 227812085 7781756 complement(419176..420918) 1 NC_012580.1 PTS system, fructose-specific IIBC component 420918 fruA-2 7781756 fruA-2 Vibrio cholerae M66-2 PTS system, fructose-specific IIBC component YP_002812095.1 419176 R 579112 CDS YP_002812096.1 227812086 7781757 complement(420931..421884) 1 NC_012580.1 1-phosphofructokinase 421884 fruK 7781757 fruK Vibrio cholerae M66-2 1-phosphofructokinase YP_002812096.1 420931 R 579112 CDS YP_002812097.1 227812087 7781758 complement(421895..423097) 1 NC_012580.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 423097 fruB 7781758 fruB Vibrio cholerae M66-2 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_002812097.1 421895 R 579112 CDS YP_002812098.1 227812088 7781759 423436..424416 1 NC_012580.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 424416 fruR 7781759 fruR Vibrio cholerae M66-2 DNA-binding transcriptional regulator FruR YP_002812098.1 423436 D 579112 CDS YP_002812099.1 227812089 7781760 424470..425609 1 NC_012580.1 putative exonuclease SbcD 425609 7781760 VCM66_A0479 Vibrio cholerae M66-2 putative exonuclease SbcD YP_002812099.1 424470 D 579112 CDS YP_002812100.1 227812090 7781761 425611..428652 1 NC_012580.1 putative exonuclease SbcC 428652 7781761 VCM66_A0480 Vibrio cholerae M66-2 putative exonuclease SbcC YP_002812100.1 425611 D 579112 CDS YP_002812101.1 227812091 7781762 428749..430809 1 NC_012580.1 sensor histidine kinase/response regulator LuxN 430809 luxN 7781762 luxN Vibrio cholerae M66-2 sensor histidine kinase/response regulator LuxN YP_002812101.1 428749 D 579112 CDS YP_002812102.1 227812092 7781763 complement(431038..432207) 1 NC_012580.1 hypothetical protein 432207 7781763 VCM66_A0482 Vibrio cholerae M66-2 hypothetical protein YP_002812102.1 431038 R 579112 CDS YP_002812103.1 227812093 7781764 complement(432404..433366) 1 NC_012580.1 hypothetical protein 433366 7781764 VCM66_A0483 Vibrio cholerae M66-2 hypothetical protein YP_002812103.1 432404 R 579112 CDS YP_002812104.1 227812094 7781765 433343..433447 1 NC_012580.1 hypothetical protein 433447 7781765 VCM66_A0484 Vibrio cholerae M66-2 hypothetical protein YP_002812104.1 433343 D 579112 CDS YP_002812105.1 227812095 7781766 complement(433513..434919) 1 NC_012580.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 434919 7781766 VCM66_A0485 Vibrio cholerae M66-2 chloride channel protein YP_002812105.1 433513 R 579112 CDS YP_002812106.1 227812096 7781767 435386..436375 1 NC_012580.1 hypothetical protein 436375 7781767 VCM66_A0486 Vibrio cholerae M66-2 hypothetical protein YP_002812106.1 435386 D 579112 CDS YP_002812107.1 227812097 7781768 complement(436439..437383) 1 NC_012580.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 437383 rbgA 7781768 rbgA Vibrio cholerae M66-2 ribosomal biogenesis GTPase YP_002812107.1 436439 R 579112 CDS YP_002812108.1 227812098 7781769 437706..439568 1 NC_012580.1 potassium uptake protein, Kup system 439568 kup 7781769 kup Vibrio cholerae M66-2 potassium uptake protein, Kup system YP_002812108.1 437706 D 579112 CDS YP_002812109.1 227812099 7781770 complement(439666..442905) 1 NC_012580.1 pyruvate-flavoredoxin oxidoreductase 442905 ydbK 7781770 ydbK Vibrio cholerae M66-2 pyruvate-flavoredoxin oxidoreductase YP_002812109.1 439666 R 579112 CDS YP_002812110.1 227812100 7781771 443008..444501 1 NC_012580.1 sensor histidine kinase 444501 7781771 VCM66_A0490 Vibrio cholerae M66-2 sensor histidine kinase YP_002812110.1 443008 D 579112 CDS YP_002812111.1 227812101 7781772 444491..445183 1 NC_012580.1 DNA-binding response regulator 445183 7781772 VCM66_A0491 Vibrio cholerae M66-2 DNA-binding response regulator YP_002812111.1 444491 D 579112 CDS YP_002812112.1 227812102 7781773 445383..445619 1 NC_012580.1 tatA protein 445619 tatA-2 7781773 tatA-2 Vibrio cholerae M66-2 tatA protein YP_002812112.1 445383 D 579112 CDS YP_002812113.1 227812103 7781774 complement(445835..446551) 1 NC_012580.1 DedA family protein 446551 7781774 VCM66_A0493 Vibrio cholerae M66-2 DedA family protein YP_002812113.1 445835 R 579112 CDS YP_002812114.1 227812104 7781775 complement(446672..447052) 1 NC_012580.1 hypothetical protein 447052 7781775 VCM66_A0494 Vibrio cholerae M66-2 hypothetical protein YP_002812114.1 446672 R 579112 CDS YP_002812115.1 227812105 7781776 complement(447186..448052) 1 NC_012580.1 hypothetical protein 448052 7781776 VCM66_A0495 Vibrio cholerae M66-2 hypothetical protein YP_002812115.1 447186 R 579112 CDS YP_002812116.1 227812106 7781777 complement(448379..449014) 1 NC_012580.1 hypothetical protein 449014 7781777 VCM66_A0496 Vibrio cholerae M66-2 hypothetical protein YP_002812116.1 448379 R 579112 CDS YP_002812117.1 227812107 7781778 449401..449946 1 NC_012580.1 putative cytochrome b561 449946 7781778 VCM66_A0497 Vibrio cholerae M66-2 putative cytochrome b561 YP_002812117.1 449401 D 579112 CDS YP_002812118.1 227812108 7781779 449943..450512 1 NC_012580.1 hypothetical protein 450512 7781779 VCM66_A0498 Vibrio cholerae M66-2 hypothetical protein YP_002812118.1 449943 D 579112 CDS YP_002812119.1 227812109 7781780 complement(450620..452071) 1 NC_012580.1 putative formate transporter 1 452071 7781780 VCM66_A0499 Vibrio cholerae M66-2 putative formate transporter 1 YP_002812119.1 450620 R 579112 CDS YP_002812120.1 227812110 7781781 452175..452270 1 NC_012580.1 hypothetical protein 452270 7781781 VCM66_A0500 Vibrio cholerae M66-2 hypothetical protein YP_002812120.1 452175 D 579112 CDS YP_002812121.1 227812111 7781782 452288..453193 1 NC_012580.1 LysR family transcriptional regulator 453193 7781782 VCM66_A0501 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812121.1 452288 D 579112 CDS YP_002812122.1 227812112 7781783 453355..453867 1 NC_012580.1 hypothetical protein 453867 7781783 VCM66_A0502 Vibrio cholerae M66-2 hypothetical protein YP_002812122.1 453355 D 579112 CDS YP_002812123.1 227812113 7781784 complement(454099..455763) 1 NC_012580.1 hypothetical protein 455763 7781784 VCM66_A0503 Vibrio cholerae M66-2 hypothetical protein YP_002812123.1 454099 R 579112 CDS YP_002812124.1 227812114 7781785 455993..457735 1 NC_012580.1 putative 5'-nucleotidase 457735 7781785 VCM66_A0504 Vibrio cholerae M66-2 putative 5'-nucleotidase YP_002812124.1 455993 D 579112 CDS YP_002812125.1 227812115 7781786 458295..459251 1 NC_012580.1 hypothetical protein 459251 7781786 VCM66_A0505 Vibrio cholerae M66-2 hypothetical protein YP_002812125.1 458295 D 579112 CDS YP_002812126.1 227812116 7781787 459555..459743 1 NC_012580.1 hypothetical protein 459743 7781787 VCM66_A0506 Vibrio cholerae M66-2 hypothetical protein YP_002812126.1 459555 D 579112 CDS YP_002812127.1 227812117 7781788 459772..459921 1 NC_012580.1 hypothetical protein 459921 7781788 VCM66_A0507 Vibrio cholerae M66-2 hypothetical protein YP_002812127.1 459772 D 579112 CDS YP_002812128.1 227812118 7781789 complement(459893..460468) 1 NC_012580.1 phnA protein 460468 phnA 7781789 phnA Vibrio cholerae M66-2 phnA protein YP_002812128.1 459893 R 579112 CDS YP_002812129.1 227812119 7781790 460652..461734 1 NC_012580.1 hypothetical protein 461734 7781790 VCM66_A0509 Vibrio cholerae M66-2 hypothetical protein YP_002812129.1 460652 D 579112 CDS YP_002812130.1 227812120 7781791 complement(461788..462018) 1 NC_012580.1 hypothetical protein 462018 7781791 VCM66_A0510 Vibrio cholerae M66-2 hypothetical protein YP_002812130.1 461788 R 579112 CDS YP_002812131.1 227812121 7781792 complement(462186..464486) 1 NC_012580.1 fatty acid cis/trans isomerase 464486 7781792 VCM66_A0511 Vibrio cholerae M66-2 fatty acid cis/trans isomerase YP_002812131.1 462186 R 579112 CDS YP_002812132.1 227812122 7781793 complement(464899..466131) 1 NC_012580.1 oxalate/formate antiporter 466131 7781793 VCM66_A0513 Vibrio cholerae M66-2 oxalate/formate antiporter YP_002812132.1 464899 R 579112 CDS YP_002812133.1 227812123 7781794 complement(466189..466308) 1 NC_012580.1 hypothetical protein 466308 7781794 VCM66_A0514 Vibrio cholerae M66-2 hypothetical protein YP_002812133.1 466189 R 579112 CDS YP_002812134.1 227812124 7781795 466542..467096 1 NC_012580.1 hypothetical protein 467096 7781795 VCM66_A0515 Vibrio cholerae M66-2 hypothetical protein YP_002812134.1 466542 D 579112 CDS YP_002812135.1 227812125 7781796 467366..468775 1 NC_012580.1 GGDEF family protein 468775 7781796 VCM66_A0516 Vibrio cholerae M66-2 GGDEF family protein YP_002812135.1 467366 D 579112 CDS YP_002812136.1 227812126 7781295 469070..470638 1 NC_012580.1 putative gamma-glutamyltranspeptidase 470638 7781295 VCM66_A0517 Vibrio cholerae M66-2 putative gamma-glutamyltranspeptidase YP_002812136.1 469070 D 579112 CDS YP_002812137.1 227812127 7781798 470713..471696 1 NC_012580.1 hypothetical protein 471696 7781798 VCM66_A0518 Vibrio cholerae M66-2 hypothetical protein YP_002812137.1 470713 D 579112 CDS YP_002812138.1 227812128 7781799 complement(471693..472931) 1 NC_012580.1 GGDEF family protein 472931 7781799 VCM66_A0519 Vibrio cholerae M66-2 GGDEF family protein YP_002812138.1 471693 R 579112 CDS YP_002812139.1 227812129 7781800 473287..473661 1 NC_012580.1 hypothetical protein 473661 7781800 VCM66_A0520 Vibrio cholerae M66-2 hypothetical protein YP_002812139.1 473287 D 579112 CDS YP_002812140.1 227812130 7781801 473671..473949 1 NC_012580.1 hypothetical protein 473949 7781801 VCM66_A0521 Vibrio cholerae M66-2 hypothetical protein YP_002812140.1 473671 D 579112 CDS YP_002812141.1 227812131 7781802 474242..475780 1 NC_012580.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 475780 pntA 7781802 pntA Vibrio cholerae M66-2 NAD(P) transhydrogenase subunit alpha YP_002812141.1 474242 D 579112 CDS YP_002812142.1 227812132 7781803 475792..477168 1 NC_012580.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 477168 pntB 7781803 pntB Vibrio cholerae M66-2 pyridine nucleotide transhydrogenase YP_002812142.1 475792 D 579112 CDS YP_002812143.1 227812133 7781804 477269..478768 1 NC_012580.1 sensor histidine kinase 478768 7781804 VCM66_A0524 Vibrio cholerae M66-2 sensor histidine kinase YP_002812143.1 477269 D 579112 CDS YP_002812144.1 227812134 7781805 478662..479399 1 NC_012580.1 transcriptional regulator 479399 7781805 VCM66_A0525 Vibrio cholerae M66-2 transcriptional regulator YP_002812144.1 478662 D 579112 CDS YP_002812145.1 227812135 7781806 479396..480286 1 NC_012580.1 hypothetical protein 480286 7781806 VCM66_A0526 Vibrio cholerae M66-2 hypothetical protein YP_002812145.1 479396 D 579112 CDS YP_002812146.1 227812136 7781807 480347..481513 1 NC_012580.1 hypothetical protein 481513 7781807 VCM66_A0527 Vibrio cholerae M66-2 hypothetical protein YP_002812146.1 480347 D 579112 CDS YP_002812147.1 227812137 7781808 481554..481715 1 NC_012580.1 hypothetical protein 481715 7781808 VCM66_A0528 Vibrio cholerae M66-2 hypothetical protein YP_002812147.1 481554 D 579112 CDS YP_002812148.1 227812138 7781809 complement(482300..482611) 1 NC_012580.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 482611 7781809 VCM66_A0529 Vibrio cholerae M66-2 translation initiation factor Sui1 YP_002812148.1 482300 R 579112 CDS YP_002812149.1 227812139 7781810 complement(482619..483002) 1 NC_012580.1 hypothetical protein 483002 7781810 VCM66_A0530 Vibrio cholerae M66-2 hypothetical protein YP_002812149.1 482619 R 579112 CDS YP_002812150.1 227812140 7781811 complement(483174..484178) 1 NC_012580.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 484178 ddl 7781811 ddl Vibrio cholerae M66-2 D-alanyl-alanine synthetase A YP_002812150.1 483174 R 579112 CDS YP_002812151.1 227812141 7781812 complement(484329..484916) 1 NC_012580.1 DamX-related protein 484916 7781812 VCM66_A0532 Vibrio cholerae M66-2 DamX-related protein YP_002812151.1 484329 R 579112 CDS YP_002812152.1 227812142 7781813 485123..487804 1 NC_012580.1 hypothetical protein 487804 7781813 VCM66_A0533 Vibrio cholerae M66-2 hypothetical protein YP_002812152.1 485123 D 579112 CDS YP_002812153.1 227812143 7781814 complement(487854..488741) 1 NC_012580.1 LysR family transcriptional regulator 488741 7781814 VCM66_A0534 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812153.1 487854 R 579112 CDS YP_002812154.1 227812144 7781815 488959..491055 1 NC_012580.1 heme transport protein HutA 491055 hutA 7781815 hutA Vibrio cholerae M66-2 heme transport protein HutA YP_002812154.1 488959 D 579112 CDS YP_002812155.1 227812145 7781816 491171..491278 1 NC_012580.1 hypothetical protein 491278 7781816 VCM66_A0536 Vibrio cholerae M66-2 hypothetical protein YP_002812155.1 491171 D 579112 CDS YP_002812156.1 227812146 7781817 complement(491379..493076) 1 NC_012580.1 hypothetical protein 493076 7781817 VCM66_A0537 Vibrio cholerae M66-2 hypothetical protein YP_002812156.1 491379 R 579112 CDS YP_002812157.1 227812147 7781818 complement(493157..493390) 1 NC_012580.1 hypothetical protein 493390 7781818 VCM66_A0538 Vibrio cholerae M66-2 hypothetical protein YP_002812157.1 493157 R 579112 CDS YP_002812158.1 227812148 7781819 complement(493391..493978) 1 NC_012580.1 hypothetical protein 493978 7781819 VCM66_A0539 Vibrio cholerae M66-2 hypothetical protein YP_002812158.1 493391 R 579112 CDS YP_002812159.1 227812149 7781820 494011..494802 1 NC_012580.1 hypothetical protein 494802 7781820 VCM66_A0540 Vibrio cholerae M66-2 hypothetical protein YP_002812159.1 494011 D 579112 CDS YP_002812160.1 227812150 7781821 complement(494914..495396) 1 NC_012580.1 hypothetical protein 495396 7781821 VCM66_A0541 Vibrio cholerae M66-2 hypothetical protein YP_002812160.1 494914 R 579112 CDS YP_002812161.1 227812151 7781822 495512..496297 1 NC_012580.1 hypothetical protein 496297 7781822 VCM66_A0542 Vibrio cholerae M66-2 hypothetical protein YP_002812161.1 495512 D 579112 CDS YP_002812162.1 227812152 7781823 complement(496383..497051) 1 NC_012580.1 putative glutathione S-transferase 497051 7781823 VCM66_A0543 Vibrio cholerae M66-2 putative glutathione S-transferase YP_002812162.1 496383 R 579112 CDS YP_002812163.1 227812153 7781824 complement(497063..497674) 1 NC_012580.1 putative glutathione S-transferase 497674 7781824 VCM66_A0544 Vibrio cholerae M66-2 putative glutathione S-transferase YP_002812163.1 497063 R 579112 CDS YP_002812164.1 227812154 7781825 497776..498372 1 NC_012580.1 hypothetical protein 498372 7781825 VCM66_A0545 Vibrio cholerae M66-2 hypothetical protein YP_002812164.1 497776 D 579112 CDS YP_002812165.1 227812155 7781826 498369..498761 1 NC_012580.1 hypothetical protein 498761 7781826 VCM66_A0546 Vibrio cholerae M66-2 hypothetical protein YP_002812165.1 498369 D 579112 CDS YP_002812166.1 227812156 7781827 complement(498845..500437) 1 NC_012580.1 putative peptide ABC transporter, ATP-binding protein 500437 7781827 VCM66_A0547 Vibrio cholerae M66-2 putative peptide ABC transporter, ATP-binding protein YP_002812166.1 498845 R 579112 CDS YP_002812167.1 227812157 7781828 complement(500434..501492) 1 NC_012580.1 putative peptide ABC transporter, permease protein 501492 7781828 VCM66_A0548 Vibrio cholerae M66-2 putative peptide ABC transporter, permease protein YP_002812167.1 500434 R 579112 CDS YP_002812168.1 227812158 7781829 complement(501489..502571) 1 NC_012580.1 putative peptide ABC transporter, permease protein 502571 7781829 VCM66_A0549 Vibrio cholerae M66-2 putative peptide ABC transporter, permease protein YP_002812168.1 501489 R 579112 CDS YP_002812169.1 227812159 7781830 complement(502580..504415) 1 NC_012580.1 putative peptide ABC transporter, periplasmic peptide-binding protein 504415 7781830 VCM66_A0550 Vibrio cholerae M66-2 putative peptide ABC transporter, periplasmic peptide-binding protein YP_002812169.1 502580 R 579112 CDS YP_002812170.1 227812160 7781831 complement(504611..505171) 1 NC_012580.1 MutT/nudix family protein 505171 7781831 VCM66_A0551 Vibrio cholerae M66-2 MutT/nudix family protein YP_002812170.1 504611 R 579112 CDS YP_002812171.1 227812161 7781832 complement(505225..506157) 1 NC_012580.1 hypothetical protein 506157 7781832 VCM66_A0552 Vibrio cholerae M66-2 hypothetical protein YP_002812171.1 505225 R 579112 CDS YP_002812172.1 227812162 7781833 506367..506648 1 NC_012580.1 hemolysin 506648 hlx 7781833 hlx Vibrio cholerae M66-2 hemolysin YP_002812172.1 506367 D 579112 CDS YP_002812173.1 227812163 7781834 complement(506730..507683) 1 NC_012580.1 hypothetical protein 507683 7781834 VCM66_A0554 Vibrio cholerae M66-2 hypothetical protein YP_002812173.1 506730 R 579112 CDS YP_002812174.1 227812164 7781835 507926..509374 1 NC_012580.1 transporter 509374 7781835 VCM66_A0555 Vibrio cholerae M66-2 transporter YP_002812174.1 507926 D 579112 CDS YP_002812175.1 227812165 7781836 complement(509386..509508) 1 NC_012580.1 hypothetical protein 509508 7781836 VCM66_A0556 Vibrio cholerae M66-2 hypothetical protein YP_002812175.1 509386 R 579112 CDS YP_002812176.1 227812166 7781837 complement(509474..510379) 1 NC_012580.1 hypothetical protein 510379 7781837 VCM66_A0557 Vibrio cholerae M66-2 hypothetical protein YP_002812176.1 509474 R 579112 CDS YP_002812177.1 227812167 7781838 complement(510445..511149) 1 NC_012580.1 putative repressor protein PhnR 511149 7781838 VCM66_A0558 Vibrio cholerae M66-2 putative repressor protein PhnR YP_002812177.1 510445 R 579112 CDS YP_002812178.1 227812168 7781839 complement(511174..512952) 1 NC_012580.1 ABC transporter permease 512952 7781839 VCM66_A0559 Vibrio cholerae M66-2 ABC transporter permease YP_002812178.1 511174 R 579112 CDS YP_002812179.1 227812169 7781840 complement(512885..514096) 1 NC_012580.1 ABC transporter ATP-binding protein 514096 7781840 VCM66_A0560 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812179.1 512885 R 579112 CDS YP_002812180.1 227812170 7781841 complement(514252..515271) 1 NC_012580.1 ABC transporter substrate-binding protein 515271 7781841 VCM66_A0561 Vibrio cholerae M66-2 ABC transporter substrate-binding protein YP_002812180.1 514252 R 579112 CDS YP_002812181.1 227812171 7781842 515503..516606 1 NC_012580.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate; 2-aminoethylphosphonate--pyruvate transaminase 516606 phnW 7781842 phnW Vibrio cholerae M66-2 2-aminoethylphosphonate--pyruvate transaminase YP_002812181.1 515503 D 579112 CDS YP_002812182.1 227812172 7781843 516624..518021 1 NC_012580.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 518021 7781843 VCM66_A0563 Vibrio cholerae M66-2 4-aminobutyrate aminotransferase YP_002812182.1 516624 D 579112 CDS YP_002812183.1 227812173 7781844 518028..518843 1 NC_012580.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate; phosphonoacetaldehyde hydrolase 518843 phnX 7781844 phnX Vibrio cholerae M66-2 phosphonoacetaldehyde hydrolase YP_002812183.1 518028 D 579112 CDS YP_002812184.1 227812174 7781845 519008..519415 1 NC_012580.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 519415 7781845 VCM66_A0565 Vibrio cholerae M66-2 nucleoside diphosphate kinase regulator YP_002812184.1 519008 D 579112 CDS YP_002812185.1 227812175 7781846 complement(519476..520150) 1 NC_012580.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 520150 7781846 VCM66_A0566 Vibrio cholerae M66-2 nucleotidase YP_002812185.1 519476 R 579112 CDS YP_002812186.1 227812176 7781847 520345..520527 1 NC_012580.1 hypothetical protein 520527 7781847 VCM66_A0567 Vibrio cholerae M66-2 hypothetical protein YP_002812186.1 520345 D 579112 CDS YP_002812187.1 227812177 7781848 520532..521182 1 NC_012580.1 isoprenoid biosynthesis protein with amidotransferase-like domain 521182 7781848 VCM66_A0568 Vibrio cholerae M66-2 isoprenoid biosynthesis protein with amidotransferase-like domain YP_002812187.1 520532 D 579112 CDS YP_002812188.1 227812178 7781849 521319..521456 1 NC_012580.1 hypothetical protein 521456 7781849 VCM66_A0569 Vibrio cholerae M66-2 hypothetical protein YP_002812188.1 521319 D 579112 CDS YP_002812189.1 227812179 7781850 521453..521863 1 NC_012580.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 521863 mscL 7781850 mscL Vibrio cholerae M66-2 large-conductance mechanosensitive channel YP_002812189.1 521453 D 579112 CDS YP_002812190.1 227812180 7781851 521896..522009 1 NC_012580.1 hypothetical protein 522009 7781851 VCM66_A0571 Vibrio cholerae M66-2 hypothetical protein YP_002812190.1 521896 D 579112 CDS YP_002812191.1 227812181 7781852 522043..523842 1 NC_012580.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 523842 fhs 7781852 fhs Vibrio cholerae M66-2 formate--tetrahydrofolate ligase YP_002812191.1 522043 D 579112 CDS YP_002812192.1 227812182 7781853 523970..525154 1 NC_012580.1 peptide methionine sulfoxide reductase 525154 7781853 VCM66_A0573 Vibrio cholerae M66-2 peptide methionine sulfoxide reductase YP_002812192.1 523970 D 579112 CDS YP_002812193.1 227812183 7781854 complement(525247..525939) 1 NC_012580.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 525939 folE 7781854 folE Vibrio cholerae M66-2 GTP cyclohydrolase I YP_002812193.1 525247 R 579112 CDS YP_002812194.1 227812184 7781855 525980..527287 1 NC_012580.1 molybdopterin biosynthesis MoeA protein 527287 moeA-2 7781855 moeA-2 Vibrio cholerae M66-2 molybdopterin biosynthesis MoeA protein YP_002812194.1 525980 D 579112 CDS YP_002812195.1 227812185 7781856 527290..528054 1 NC_012580.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 528054 moeB 7781856 moeB Vibrio cholerae M66-2 molybdopterin biosynthesis protein MoeB YP_002812195.1 527290 D 579112 CDS YP_002812196.1 227812186 7781857 528238..528606 1 NC_012580.1 hypothetical protein 528606 7781857 VCM66_A0577 Vibrio cholerae M66-2 hypothetical protein YP_002812196.1 528238 D 579112 CDS YP_002812197.1 227812187 7781858 528628..529458 1 NC_012580.1 putative thiosulfate sulfurtransferase SseA 529458 7781858 VCM66_A0578 Vibrio cholerae M66-2 putative thiosulfate sulfurtransferase SseA YP_002812197.1 528628 D 579112 CDS YP_002812198.1 227812188 7781859 complement(529543..530538) 1 NC_012580.1 transcriptional regulator, SorC family 530538 7781859 VCM66_A0579 Vibrio cholerae M66-2 transcriptional regulator, SorC family YP_002812198.1 529543 R 579112 CDS YP_002812199.1 227812189 7780805 530537..530647 1 NC_012580.1 hypothetical protein 530647 7780805 VCM66_A0580 Vibrio cholerae M66-2 hypothetical protein YP_002812199.1 530537 D 579112 CDS YP_002812200.1 227812190 7780806 531131..532081 1 NC_012580.1 transaldolase B 532081 talB 7780806 talB Vibrio cholerae M66-2 transaldolase B YP_002812200.1 531131 D 579112 CDS YP_002812201.1 227812191 7780807 532130..534172 1 NC_012580.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 534172 tktA-2 7780807 tktA-2 Vibrio cholerae M66-2 transketolase YP_002812201.1 532130 D 579112 CDS YP_002812202.1 227812192 7780808 complement(534289..536643) 1 NC_012580.1 heme receptor HasR 536643 hasR 7780808 hasR Vibrio cholerae M66-2 heme receptor HasR YP_002812202.1 534289 R 579112 CDS YP_002812203.1 227812193 7780809 536613..536717 1 NC_012580.1 hypothetical protein 536717 7780809 VCM66_A0584 Vibrio cholerae M66-2 hypothetical protein YP_002812203.1 536613 D 579112 CDS YP_002812204.1 227812194 7780810 536857..537369 1 NC_012580.1 putative rRNA methylase 537369 7780810 VCM66_A0585 Vibrio cholerae M66-2 putative rRNA methylase YP_002812204.1 536857 D 579112 CDS YP_002812205.1 227812195 7780811 537807..539981 1 NC_012580.1 SecA-related protein 539981 7780811 VCM66_A0586 Vibrio cholerae M66-2 SecA-related protein YP_002812205.1 537807 D 579112 CDS YP_002812206.1 227812196 7780812 complement(540252..541292) 1 NC_012580.1 hypothetical protein 541292 7780812 VCM66_A0587 Vibrio cholerae M66-2 hypothetical protein YP_002812206.1 540252 R 579112 CDS YP_002812207.1 227812197 7780813 complement(541305..542276) 1 NC_012580.1 D-3-phosphoglycerate dehydrogenase-related protein 542276 7780813 VCM66_A0588 Vibrio cholerae M66-2 D-3-phosphoglycerate dehydrogenase-related protein YP_002812207.1 541305 R 579112 CDS YP_002812208.1 227812198 7780814 complement(542292..542807) 1 NC_012580.1 hypothetical protein 542807 7780814 VCM66_A0589 Vibrio cholerae M66-2 hypothetical protein YP_002812208.1 542292 R 579112 CDS YP_002812209.1 227812199 7780815 complement(542840..543289) 1 NC_012580.1 MutT/nudix family protein 543289 7780815 VCM66_A0590 Vibrio cholerae M66-2 MutT/nudix family protein YP_002812209.1 542840 R 579112 CDS YP_002812210.1 227812200 7780816 complement(543329..543679) 1 NC_012580.1 glpM protein 543679 glpM 7780816 glpM Vibrio cholerae M66-2 glpM protein YP_002812210.1 543329 R 579112 CDS YP_002812211.1 227812201 7780817 543871..544596 1 NC_012580.1 hypothetical protein 544596 7780817 VCM66_A0592 Vibrio cholerae M66-2 hypothetical protein YP_002812211.1 543871 D 579112 CDS YP_002812212.1 227812202 7780818 544606..545547 1 NC_012580.1 LysR family transcriptional regulator 545547 7780818 VCM66_A0593 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812212.1 544606 D 579112 CDS YP_002812213.1 227812203 7780819 complement(545544..545834) 1 NC_012580.1 hypothetical protein 545834 7780819 VCM66_A0594 Vibrio cholerae M66-2 hypothetical protein YP_002812213.1 545544 R 579112 CDS YP_002812214.1 227812204 7780820 complement(545838..546491) 1 NC_012580.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 546491 7780820 VCM66_A0595 Vibrio cholerae M66-2 dihydropteridine reductase YP_002812214.1 545838 R 579112 CDS YP_002812215.1 227812205 7780821 complement(546707..549910) 1 NC_012580.1 transporter, AcrB/D/F family 549910 7780821 VCM66_A0596 Vibrio cholerae M66-2 transporter, AcrB/D/F family YP_002812215.1 546707 R 579112 CDS YP_002812216.1 227812206 7780822 complement(549867..550871) 1 NC_012580.1 AcrA/AcrE family protein 550871 7780822 VCM66_A0597 Vibrio cholerae M66-2 AcrA/AcrE family protein YP_002812216.1 549867 R 579112 CDS YP_002812217.1 227812207 7780823 complement(550981..551445) 1 NC_012580.1 hypothetical protein 551445 7780823 VCM66_A0598 Vibrio cholerae M66-2 hypothetical protein YP_002812217.1 550981 R 579112 CDS YP_002812218.1 227812208 7780824 complement(551450..551869) 1 NC_012580.1 hypothetical protein 551869 7780824 VCM66_A0599 Vibrio cholerae M66-2 hypothetical protein YP_002812218.1 551450 R 579112 CDS YP_002812219.1 227812209 7780825 complement(551886..552203) 1 NC_012580.1 transcriptional regulator, ArsR family 552203 7780825 VCM66_A0600 Vibrio cholerae M66-2 transcriptional regulator, ArsR family YP_002812219.1 551886 R 579112 CDS YP_002812220.1 227812210 7780826 552277..552543 1 NC_012580.1 hypothetical protein 552543 7780826 VCM66_A0601 Vibrio cholerae M66-2 hypothetical protein YP_002812220.1 552277 D 579112 CDS YP_002812221.1 227812211 7780827 552609..554312 1 NC_012580.1 putative NADH oxidase 554312 7780827 VCM66_A0602 Vibrio cholerae M66-2 putative NADH oxidase YP_002812221.1 552609 D 579112 CDS YP_002812222.1 227812212 7780828 complement(554405..554785) 1 NC_012580.1 hypothetical protein 554785 7780828 VCM66_A0603 Vibrio cholerae M66-2 hypothetical protein YP_002812222.1 554405 R 579112 CDS YP_002812223.1 227812213 7780829 complement(554901..556718) 1 NC_012580.1 hemolysin 556718 7780829 VCM66_A0604 Vibrio cholerae M66-2 hemolysin YP_002812223.1 554901 R 579112 CDS YP_002812224.1 227812214 7780830 complement(556643..557089) 1 NC_012580.1 hypothetical protein 557089 7780830 VCM66_A0605 Vibrio cholerae M66-2 hypothetical protein YP_002812224.1 556643 R 579112 CDS YP_002812225.1 227812215 7780831 complement(557100..557846) 1 NC_012580.1 hypothetical protein 557846 7780831 VCM66_A0606 Vibrio cholerae M66-2 hypothetical protein YP_002812225.1 557100 R 579112 CDS YP_002812226.1 227812216 7780832 complement(557846..558388) 1 NC_012580.1 hypothetical protein 558388 7780832 VCM66_A0607 Vibrio cholerae M66-2 hypothetical protein YP_002812226.1 557846 R 579112 CDS YP_002812227.1 227812217 7780833 complement(558477..559613) 1 NC_012580.1 hypothetical protein 559613 7780833 VCM66_A0608 Vibrio cholerae M66-2 hypothetical protein YP_002812227.1 558477 R 579112 CDS YP_002812228.1 227812218 7780834 complement(559610..560191) 1 NC_012580.1 hypothetical protein 560191 7780834 VCM66_A0609 Vibrio cholerae M66-2 hypothetical protein YP_002812228.1 559610 R 579112 CDS YP_002812229.1 227812219 7780835 560463..560900 1 NC_012580.1 hypothetical protein 560900 7780835 VCM66_A0610 Vibrio cholerae M66-2 hypothetical protein YP_002812229.1 560463 D 579112 CDS YP_002812230.1 227812220 7780836 complement(561066..562505) 1 NC_012580.1 PTS system, sucrose-specific IIBC component 562505 scrA 7780836 scrA Vibrio cholerae M66-2 PTS system, sucrose-specific IIBC component YP_002812230.1 561066 R 579112 CDS YP_002812231.1 227812221 7780837 562806..563798 1 NC_012580.1 putative sucrose operon repressor ScrR 563798 7780837 VCM66_A0612 Vibrio cholerae M66-2 putative sucrose operon repressor ScrR YP_002812231.1 562806 D 579112 CDS YP_002812232.1 227812222 7780838 563874..565520 1 NC_012580.1 sucrose-6-phosphate dehydrogenase 565520 cscA 7780838 cscA Vibrio cholerae M66-2 sucrose-6-phosphate dehydrogenase YP_002812232.1 563874 D 579112 CDS YP_002812233.1 227812223 7780839 complement(565642..566613) 1 NC_012580.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 566613 cscK 7780839 cscK Vibrio cholerae M66-2 aminoimidazole riboside kinase YP_002812233.1 565642 R 579112 CDS YP_002812234.1 227812224 7780840 566960..568498 1 NC_012580.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 568498 glpD 7780840 glpD Vibrio cholerae M66-2 glycerol-3-phosphate dehydrogenase YP_002812234.1 566960 D 579112 CDS YP_002812235.1 227812225 7780841 complement(568600..570210) 1 NC_012580.1 methyl-accepting chemotaxis protein 570210 7780841 VCM66_A0616 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812235.1 568600 R 579112 CDS YP_002812236.1 227812226 7780842 complement(570396..571019) 1 NC_012580.1 protein F-related protein 571019 7780842 VCM66_A0617 Vibrio cholerae M66-2 protein F-related protein YP_002812236.1 570396 R 579112 CDS YP_002812237.1 227812227 7780843 complement(571020..571142) 1 NC_012580.1 hypothetical protein 571142 7780843 VCM66_A0618 Vibrio cholerae M66-2 hypothetical protein YP_002812237.1 571020 R 579112 CDS YP_002812238.1 227812228 7780844 571232..571705 1 NC_012580.1 peptidyl-prolyl cis-trans isomerase-related protein 571705 7780844 VCM66_A0619 Vibrio cholerae M66-2 peptidyl-prolyl cis-trans isomerase-related protein YP_002812238.1 571232 D 579112 CDS YP_002812239.1 227812229 7780845 complement(571786..572424) 1 NC_012580.1 CbbY family protein 572424 7780845 VCM66_A0620 Vibrio cholerae M66-2 CbbY family protein YP_002812239.1 571786 R 579112 CDS YP_002812240.1 227812230 7780846 572571..574334 1 NC_012580.1 methyl-accepting chemotaxis protein 574334 7780846 VCM66_A0621 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812240.1 572571 D 579112 CDS YP_002812241.1 227812231 7780847 complement(574275..574463) 1 NC_012580.1 hypothetical protein 574463 7780847 VCM66_A0622 Vibrio cholerae M66-2 hypothetical protein YP_002812241.1 574275 R 579112 CDS YP_002812242.1 227812232 7780848 574728..576107 1 NC_012580.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 576107 dcuC 7780848 dcuC Vibrio cholerae M66-2 C4-dicarboxylate transporter DcuC YP_002812242.1 574728 D 579112 CDS YP_002812243.1 227812233 7780849 complement(576205..577635) 1 NC_012580.1 L-serine dehydratase 1 577635 sdaA-2 7780849 sdaA-2 Vibrio cholerae M66-2 L-serine dehydratase 1 YP_002812243.1 576205 R 579112 CDS YP_002812244.1 227812234 7780850 complement(577586..579127) 1 NC_012580.1 sodium/solute symporter 579127 7780850 VCM66_A0625 Vibrio cholerae M66-2 sodium/solute symporter YP_002812244.1 577586 R 579112 CDS YP_002812245.1 227812235 7780851 complement(579166..579273) 1 NC_012580.1 hypothetical protein 579273 7780851 VCM66_A0626 Vibrio cholerae M66-2 hypothetical protein YP_002812245.1 579166 R 579112 CDS YP_002812246.1 227812236 7780852 579466..580761 1 NC_012580.1 sugar transporter family protein 580761 7780852 VCM66_A0627 Vibrio cholerae M66-2 sugar transporter family protein YP_002812246.1 579466 D 579112 CDS YP_002812247.1 227812237 7780853 complement(580720..580875) 1 NC_012580.1 hypothetical protein 580875 7780853 VCM66_A0628 Vibrio cholerae M66-2 hypothetical protein YP_002812247.1 580720 R 579112 CDS YP_002812248.1 227812238 7780854 580858..581874 1 NC_012580.1 hypothetical protein 581874 7780854 VCM66_A0629 Vibrio cholerae M66-2 hypothetical protein YP_002812248.1 580858 D 579112 CDS YP_002812249.1 227812239 7780855 581974..582084 1 NC_012580.1 hypothetical protein 582084 7780855 VCM66_A0630 Vibrio cholerae M66-2 hypothetical protein YP_002812249.1 581974 D 579112 CDS YP_002812250.1 227812240 7780856 582114..583145 1 NC_012580.1 transcriptional regulator, LacI family 583145 7780856 VCM66_A0631 Vibrio cholerae M66-2 transcriptional regulator, LacI family YP_002812250.1 582114 D 579112 CDS YP_002812251.1 227812241 7780857 complement(583196..583822) 1 NC_012580.1 nitrate/nitrite response regulator NarP 583822 narP 7780857 narP Vibrio cholerae M66-2 nitrate/nitrite response regulator NarP YP_002812251.1 583196 R 579112 CDS YP_002812252.1 227812242 7780858 complement(583812..585563) 1 NC_012580.1 nitrate/nitrite sensor protein NarQ 585563 narQ 7780858 narQ Vibrio cholerae M66-2 nitrate/nitrite sensor protein NarQ YP_002812252.1 583812 R 579112 CDS YP_002812253.1 227812243 7780859 585721..586227 1 NC_012580.1 iron-sulfur cluster-binding protein NapF 586227 napF 7780859 napF Vibrio cholerae M66-2 iron-sulfur cluster-binding protein NapF YP_002812253.1 585721 D 579112 CDS YP_002812254.1 227812244 7780860 586233..586574 1 NC_012580.1 napD protein 586574 napD 7780860 napD Vibrio cholerae M66-2 napD protein YP_002812254.1 586233 D 579112 CDS YP_002812255.1 227812245 7780861 586571..589060 1 NC_012580.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 589060 napA 7780861 napA Vibrio cholerae M66-2 nitrate reductase catalytic subunit YP_002812255.1 586571 D 579112 CDS YP_002812256.1 227812246 7780862 589067..589582 1 NC_012580.1 periplasmic nitrate reductase, cytochrome c-type protein 589582 napB 7780862 napB Vibrio cholerae M66-2 periplasmic nitrate reductase, cytochrome c-type protein YP_002812256.1 589067 D 579112 CDS YP_002812257.1 227812247 7780863 589600..590175 1 NC_012580.1 periplasmic nitrate reductase, cytochrome c-type protein 590175 napC 7780863 napC Vibrio cholerae M66-2 periplasmic nitrate reductase, cytochrome c-type protein YP_002812257.1 589600 D 579112 CDS YP_002812258.1 227812248 7780864 complement(590359..591654) 1 NC_012580.1 hypothetical protein 591654 7780864 VCM66_A0639 Vibrio cholerae M66-2 hypothetical protein YP_002812258.1 590359 R 579112 CDS YP_002812259.1 227812249 7780865 591813..592439 1 NC_012580.1 transcriptional regulator UhpA 592439 uhpA 7780865 uhpA Vibrio cholerae M66-2 transcriptional regulator UhpA YP_002812259.1 591813 D 579112 CDS YP_002812260.1 227812250 7780866 592442..594025 1 NC_012580.1 sensor protein UhpB 594025 uhpB 7780866 uhpB Vibrio cholerae M66-2 sensor protein UhpB YP_002812260.1 592442 D 579112 CDS YP_002812261.1 227812251 7780867 594093..595403 1 NC_012580.1 membrane protein regulates uhpT expression; regulatory protein UhpC 595403 uhpC 7780867 uhpC Vibrio cholerae M66-2 regulatory protein UhpC YP_002812261.1 594093 D 579112 CDS YP_002812262.1 227812252 7780868 595516..596550 1 NC_012580.1 iron(III) ABC transporter, periplasmic iron-compound-binding protein 596550 7780868 VCM66_A0643 Vibrio cholerae M66-2 iron(III) ABC transporter, periplasmic iron-compound-binding protein YP_002812262.1 595516 D 579112 CDS YP_002812263.1 227812253 7780869 596654..598756 1 NC_012580.1 iron(III) ABC transporter, permease protein 598756 7780869 VCM66_A0644 Vibrio cholerae M66-2 iron(III) ABC transporter, permease protein YP_002812263.1 596654 D 579112 CDS YP_002812264.1 227812254 7780870 598768..599823 1 NC_012580.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 599823 fbpC 7780870 fbpC Vibrio cholerae M66-2 ferric transporter ATP-binding subunit YP_002812264.1 598768 D 579112 CDS YP_002812265.1 227812255 7780871 complement(599909..601684) 1 NC_012580.1 polyhydroxyalkanoic acid synthase 601684 phaC 7780871 phaC Vibrio cholerae M66-2 polyhydroxyalkanoic acid synthase YP_002812265.1 599909 R 579112 CDS YP_002812266.1 227812256 7780872 complement(601742..602089) 1 NC_012580.1 hypothetical protein 602089 7780872 VCM66_A0647 Vibrio cholerae M66-2 hypothetical protein YP_002812266.1 601742 R 579112 CDS YP_002812267.1 227812257 7780873 complement(602119..603324) 1 NC_012580.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 603324 7780873 VCM66_A0648 Vibrio cholerae M66-2 acetyl-CoA acetyltransferase YP_002812267.1 602119 R 579112 CDS YP_002812268.1 227812258 7780874 complement(603337..604077) 1 NC_012580.1 catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; acetoacetyl-CoA reductase 604077 7780874 VCM66_A0649 Vibrio cholerae M66-2 acetoacetyl-CoA reductase YP_002812268.1 603337 R 579112 CDS YP_002812269.1 227812259 7780875 complement(604748..605650) 1 NC_012580.1 protein-export membrane protein SecF 605650 secF-2 7780875 secF-2 Vibrio cholerae M66-2 protein-export membrane protein SecF YP_002812269.1 604748 R 579112 CDS YP_002812270.1 227812260 7780876 complement(605654..607492) 1 NC_012580.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 607492 secD 7780876 secD Vibrio cholerae M66-2 preprotein translocase subunit SecD YP_002812270.1 605654 R 579112 CDS YP_002812271.1 227812261 7780877 complement(607564..608019) 1 NC_012580.1 hypothetical protein 608019 7780877 VCM66_A0652 Vibrio cholerae M66-2 hypothetical protein YP_002812271.1 607564 R 579112 CDS YP_002812272.1 227812262 7780878 complement(608096..608767) 1 NC_012580.1 hypothetical protein 608767 7780878 VCM66_A0653 Vibrio cholerae M66-2 hypothetical protein YP_002812272.1 608096 R 579112 CDS YP_002812273.1 227812263 7780879 complement(608802..608912) 1 NC_012580.1 hypothetical protein 608912 7780879 VCM66_A0654 Vibrio cholerae M66-2 hypothetical protein YP_002812273.1 608802 R 579112 CDS YP_002812274.1 227812264 7780880 609125..611053 1 NC_012580.1 sensory box/GGDEF family protein 611053 7780880 VCM66_A0655 Vibrio cholerae M66-2 sensory box/GGDEF family protein YP_002812274.1 609125 D 579112 CDS YP_002812275.1 227812265 7780881 611050..611142 1 NC_012580.1 hypothetical protein 611142 7780881 VCM66_A0656 Vibrio cholerae M66-2 hypothetical protein YP_002812275.1 611050 D 579112 CDS YP_002812276.1 227812266 7780882 611356..612579 1 NC_012580.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 612579 glgC 7780882 glgC Vibrio cholerae M66-2 glucose-1-phosphate adenylyltransferase YP_002812276.1 611356 D 579112 CDS YP_002812277.1 227812267 7780883 complement(612845..616000) 1 NC_012580.1 chitodextrinase 616000 7780883 VCM66_A0658 Vibrio cholerae M66-2 chitodextrinase YP_002812277.1 612845 R 579112 CDS YP_002812278.1 227812268 7780884 complement(616034..616165) 1 NC_012580.1 hypothetical protein 616165 7780884 VCM66_A0659 Vibrio cholerae M66-2 hypothetical protein YP_002812278.1 616034 R 579112 CDS YP_002812279.1 227812269 7780885 616672..617820 1 NC_012580.1 iron-containing alcohol dehydrogenase 617820 7780885 VCM66_A0660 Vibrio cholerae M66-2 iron-containing alcohol dehydrogenase YP_002812279.1 616672 D 579112 CDS YP_002812280.1 227812270 7780886 617899..618588 1 NC_012580.1 hypothetical protein 618588 7780886 VCM66_A0661 Vibrio cholerae M66-2 hypothetical protein YP_002812280.1 617899 D 579112 CDS YP_002812281.1 227812271 7780887 complement(618585..619904) 1 NC_012580.1 phosphoglycerate transport system transcriptional regulatory protein PgtA 619904 7780887 VCM66_A0662 Vibrio cholerae M66-2 phosphoglycerate transport system transcriptional regulatory protein PgtA YP_002812281.1 618585 R 579112 CDS YP_002812282.1 227812272 7780888 complement(619822..622191) 1 NC_012580.1 putative phosphoglycerate transport regulatory protein PgtB 622191 7780888 VCM66_A0663 Vibrio cholerae M66-2 putative phosphoglycerate transport regulatory protein PgtB YP_002812282.1 619822 R 579112 CDS YP_002812283.1 227812273 7780889 complement(622188..623510) 1 NC_012580.1 putative phosphoglycerate transport regulatory protein PgtC 623510 7780889 VCM66_A0664 Vibrio cholerae M66-2 putative phosphoglycerate transport regulatory protein PgtC YP_002812283.1 622188 R 579112 CDS YP_002812284.1 227812274 7780890 623757..625136 1 NC_012580.1 putative regulatory protein UhpC 625136 7780890 VCM66_A0665 Vibrio cholerae M66-2 putative regulatory protein UhpC YP_002812284.1 623757 D 579112 CDS YP_002812285.1 227812275 7780891 625258..626718 1 NC_012580.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 626718 pykA-2 7780891 pykA-2 Vibrio cholerae M66-2 pyruvate kinase YP_002812285.1 625258 D 579112 CDS YP_002812286.1 227812276 7780892 complement(626837..629899) 1 NC_012580.1 sensor protein TorS 629899 torS 7780892 torS Vibrio cholerae M66-2 sensor protein TorS YP_002812286.1 626837 R 579112 CDS YP_002812287.1 227812277 7780893 629822..630871 1 NC_012580.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 630871 torT 7780893 torT Vibrio cholerae M66-2 TMAO reductase system periplasmic protein TorT YP_002812287.1 629822 D 579112 CDS YP_002812288.1 227812278 7780894 630926..631381 1 NC_012580.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 631381 mgsA 7780894 mgsA Vibrio cholerae M66-2 methylglyoxal synthase YP_002812288.1 630926 D 579112 CDS YP_002812289.1 227812279 7780895 complement(631450..632070) 1 NC_012580.1 pyrazinamidase/nicotinamidase 632070 pncA 7780895 pncA Vibrio cholerae M66-2 pyrazinamidase/nicotinamidase YP_002812289.1 631450 R 579112 CDS YP_002812290.1 227812280 7780896 complement(632192..632308) 1 NC_012580.1 hypothetical protein 632308 7780896 VCM66_A0671 Vibrio cholerae M66-2 hypothetical protein YP_002812290.1 632192 R 579112 CDS YP_002812291.1 227812281 7780897 632375..632731 1 NC_012580.1 diacylglycerol kinase 632731 dgkA 7780897 dgkA Vibrio cholerae M66-2 diacylglycerol kinase YP_002812291.1 632375 D 579112 CDS YP_002812292.1 227812282 7780898 632871..633188 1 NC_012580.1 hypothetical protein 633188 7780898 VCM66_A0673 Vibrio cholerae M66-2 hypothetical protein YP_002812292.1 632871 D 579112 CDS YP_002812293.1 227812283 7780899 633181..633717 1 NC_012580.1 hypothetical protein 633717 7780899 VCM66_A0674 Vibrio cholerae M66-2 hypothetical protein YP_002812293.1 633181 D 579112 CDS YP_002812294.1 227812284 7780900 complement(633773..635872) 1 NC_012580.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 635872 helD 7780900 helD Vibrio cholerae M66-2 DNA helicase IV YP_002812294.1 633773 R 579112 CDS YP_002812295.1 227812285 7780901 636023..638200 1 NC_012580.1 hypothetical protein 638200 7780901 VCM66_A0676 Vibrio cholerae M66-2 hypothetical protein YP_002812295.1 636023 D 579112 CDS YP_002812296.1 227812286 7780902 complement(638210..639157) 1 NC_012580.1 sensor histide kinase 639157 7780902 VCM66_A0677 Vibrio cholerae M66-2 sensor histide kinase YP_002812296.1 638210 R 579112 CDS YP_002812297.1 227812287 7780903 complement(639154..639729) 1 NC_012580.1 guanylate cyclase-related protein 639729 7780903 VCM66_A0678 Vibrio cholerae M66-2 guanylate cyclase-related protein YP_002812297.1 639154 R 579112 CDS YP_002812298.1 227812288 7780904 639857..640168 1 NC_012580.1 hypothetical protein 640168 7780904 VCM66_A0679 Vibrio cholerae M66-2 hypothetical protein YP_002812298.1 639857 D 579112 CDS YP_002812299.1 227812289 7780905 640225..640515 1 NC_012580.1 hypothetical protein 640515 7780905 VCM66_A0680 Vibrio cholerae M66-2 hypothetical protein YP_002812299.1 640225 D 579112 CDS YP_002812300.1 227812290 7780906 640545..641855 1 NC_012580.1 3-hydroxy-3-methylglutaryl CoA reductase 641855 hmgA 7780906 hmgA Vibrio cholerae M66-2 3-hydroxy-3-methylglutaryl CoA reductase YP_002812300.1 640545 D 579112 CDS YP_002812301.1 227812291 7780907 complement(641954..643054) 1 NC_012580.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 643054 modC 7780907 modC Vibrio cholerae M66-2 molybdate transporter ATP-binding protein YP_002812301.1 641954 R 579112 CDS YP_002812302.1 227812292 7780908 complement(643068..643766) 1 NC_012580.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 643766 modB 7780908 modB Vibrio cholerae M66-2 molybdate ABC transporter permease YP_002812302.1 643068 R 579112 CDS YP_002812303.1 227812293 7780909 complement(643767..644531) 1 NC_012580.1 molybdenum ABC transporter, periplasmic molybdate-binding protein 644531 modA 7780909 modA Vibrio cholerae M66-2 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_002812303.1 643767 R 579112 CDS YP_002812304.1 227812294 7780910 complement(644537..646045) 1 NC_012580.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 646045 cobQ 7780910 cobQ Vibrio cholerae M66-2 cobyric acid synthase YP_002812304.1 644537 R 579112 CDS YP_002812305.1 227812295 7780911 complement(646594..648765) 1 NC_012580.1 hypothetical protein 648765 7780911 VCM66_A0686 Vibrio cholerae M66-2 hypothetical protein YP_002812305.1 646594 R 579112 CDS YP_002812306.1 227812296 7780912 complement(648758..649381) 1 NC_012580.1 hypothetical protein 649381 7780912 VCM66_A0687 Vibrio cholerae M66-2 hypothetical protein YP_002812306.1 648758 R 579112 CDS YP_002812307.1 227812297 7780913 complement(649384..651213) 1 NC_012580.1 hypothetical protein 651213 7780913 VCM66_A0688 Vibrio cholerae M66-2 hypothetical protein YP_002812307.1 649384 R 579112 CDS YP_002812308.1 227812298 7780914 complement(651912..652217) 1 NC_012580.1 hypothetical protein 652217 7780914 VCM66_A0689 Vibrio cholerae M66-2 hypothetical protein YP_002812308.1 651912 R 579112 CDS YP_002812309.1 227812299 7780915 652420..652818 1 NC_012580.1 hypothetical protein 652818 7780915 VCM66_A0690 Vibrio cholerae M66-2 hypothetical protein YP_002812309.1 652420 D 579112 CDS YP_002812310.1 227812300 7780916 652859..653011 1 NC_012580.1 hypothetical protein 653011 7780916 VCM66_A0691 Vibrio cholerae M66-2 hypothetical protein YP_002812310.1 652859 D 579112 CDS YP_002812311.1 227812301 7780917 653049..653588 1 NC_012580.1 hypothetical protein 653588 7780917 VCM66_A0692 Vibrio cholerae M66-2 hypothetical protein YP_002812311.1 653049 D 579112 CDS YP_002812312.1 227812302 7780918 653787..654497 1 NC_012580.1 hypothetical protein 654497 7780918 VCM66_A0693 Vibrio cholerae M66-2 hypothetical protein YP_002812312.1 653787 D 579112 CDS YP_002812313.1 227812303 7780919 complement(654489..657062) 1 NC_012580.1 sensor histidine kinase LuxQ 657062 luxQ 7780919 luxQ Vibrio cholerae M66-2 sensor histidine kinase LuxQ YP_002812313.1 654489 R 579112 CDS YP_002812314.1 227812304 7780920 complement(657080..658174) 1 NC_012580.1 luxP protein 658174 luxP 7780920 luxP Vibrio cholerae M66-2 luxP protein YP_002812314.1 657080 R 579112 CDS YP_002812315.1 227812305 7780921 complement(658386..659627) 1 NC_012580.1 hypothetical protein 659627 7780921 VCM66_A0696 Vibrio cholerae M66-2 hypothetical protein YP_002812315.1 658386 R 579112 CDS YP_002812316.1 227812306 7780922 complement(659648..659953) 1 NC_012580.1 hypothetical protein 659953 7780922 VCM66_A0697 Vibrio cholerae M66-2 hypothetical protein YP_002812316.1 659648 R 579112 CDS YP_002812317.1 227812307 7780923 complement(659970..660620) 1 NC_012580.1 hypothetical protein 660620 7780923 VCM66_A0698 Vibrio cholerae M66-2 hypothetical protein YP_002812317.1 659970 R 579112 CDS YP_002812318.1 227812308 7780924 complement(660662..660859) 1 NC_012580.1 hypothetical protein 660859 7780924 VCM66_A0699 Vibrio cholerae M66-2 hypothetical protein YP_002812318.1 660662 R 579112 CDS YP_002812319.1 227812309 7780925 661047..661367 1 NC_012580.1 hypothetical protein 661367 7780925 VCM66_A0700 Vibrio cholerae M66-2 hypothetical protein YP_002812319.1 661047 D 579112 CDS YP_002812320.1 227812310 7780926 661367..661516 1 NC_012580.1 hypothetical protein 661516 7780926 VCM66_A0701 Vibrio cholerae M66-2 hypothetical protein YP_002812320.1 661367 D 579112 CDS YP_002812321.1 227812311 7780927 661780..662031 1 NC_012580.1 hypothetical protein 662031 7780927 VCM66_A0702 Vibrio cholerae M66-2 hypothetical protein YP_002812321.1 661780 D 579112 CDS YP_002812322.1 227812312 7780928 complement(662112..663629) 1 NC_012580.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 663629 glpK 7780928 glpK Vibrio cholerae M66-2 glycerol kinase YP_002812322.1 662112 R 579112 CDS YP_002812323.1 227812313 7780929 complement(663741..664595) 1 NC_012580.1 glycerol uptake facilitator protein 664595 glpF 7780929 glpF Vibrio cholerae M66-2 glycerol uptake facilitator protein YP_002812323.1 663741 R 579112 CDS YP_002812324.1 227812314 7780930 complement(664933..665094) 1 NC_012580.1 hypothetical protein 665094 7780930 VCM66_A0705 Vibrio cholerae M66-2 hypothetical protein YP_002812324.1 664933 R 579112 CDS YP_002812325.1 227812315 7780931 665250..666893 1 NC_012580.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 666893 glpA 7780931 glpA Vibrio cholerae M66-2 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002812325.1 665250 D 579112 CDS YP_002812326.1 227812316 7780932 666890..668200 1 NC_012580.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 668200 glpB 7780932 glpB Vibrio cholerae M66-2 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002812326.1 666890 D 579112 CDS YP_002812327.1 227812317 7780933 668197..669438 1 NC_012580.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 669438 glpC 7780933 glpC Vibrio cholerae M66-2 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002812327.1 668197 D 579112 CDS YP_002812328.1 227812318 7780934 complement(669580..670791) 1 NC_012580.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; 3-oxoacyl-(acyl carrier protein) synthase III 670791 fabH-2 7780934 fabH-2 Vibrio cholerae M66-2 3-oxoacyl-(acyl carrier protein) synthase III YP_002812328.1 669580 R 579112 CDS YP_002812329.1 227812319 7780935 670837..671271 1 NC_012580.1 thioredoxin 2 671271 trxC 7780935 trxC Vibrio cholerae M66-2 thioredoxin 2 YP_002812329.1 670837 D 579112 CDS YP_002812330.1 227812320 7780936 671460..672614 1 NC_012580.1 hypothetical protein 672614 7780936 VCM66_A0712 Vibrio cholerae M66-2 hypothetical protein YP_002812330.1 671460 D 579112 CDS YP_002812331.1 227812321 7780937 672699..673529 1 NC_012580.1 lipase-related protein 673529 7780937 VCM66_A0713 Vibrio cholerae M66-2 lipase-related protein YP_002812331.1 672699 D 579112 CDS YP_002812332.1 227812322 7781297 complement(673963..674463) 1 NC_012580.1 hypothetical protein 674463 7781297 VCM66_A0714 Vibrio cholerae M66-2 hypothetical protein YP_002812332.1 673963 R 579112 CDS YP_002812333.1 227812323 7780939 674578..675543 1 NC_012580.1 LysR family transcriptional regulator 675543 7780939 VCM66_A0715 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812333.1 674578 D 579112 CDS YP_002812334.1 227812324 7780940 complement(675596..676264) 1 NC_012580.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 676264 artM 7780940 artM Vibrio cholerae M66-2 arginine transporter permease subunit ArtM YP_002812334.1 675596 R 579112 CDS YP_002812335.1 227812325 7780941 complement(676261..676950) 1 NC_012580.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 676950 artQ 7780941 artQ Vibrio cholerae M66-2 arginine transporter permease subunit ArtQ YP_002812335.1 676261 R 579112 CDS YP_002812336.1 227812326 7780942 complement(676952..677683) 1 NC_012580.1 arginine ABC transporter, periplasmic arginine-binding protein 677683 artI 7780942 artI Vibrio cholerae M66-2 arginine ABC transporter, periplasmic arginine-binding protein YP_002812336.1 676952 R 579112 CDS YP_002812337.1 227812327 7780943 complement(677757..678500) 1 NC_012580.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 678500 artP 7780943 artP Vibrio cholerae M66-2 arginine transporter ATP-binding subunit YP_002812337.1 677757 R 579112 CDS YP_002812338.1 227812328 7781298 678939..679037 1 NC_012580.1 hypothetical protein 679037 7781298 VCM66_A0720 Vibrio cholerae M66-2 hypothetical protein YP_002812338.1 678939 D 579112 CDS YP_002812339.1 227812329 7780945 complement(679078..680523) 1 NC_012580.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 680523 yieM 7780945 yieM Vibrio cholerae M66-2 hypothetical protein YP_002812339.1 679078 R 579112 CDS YP_002812340.1 227812330 7780946 complement(680532..682190) 1 NC_012580.1 hypothetical protein 682190 7780946 VCM66_A0722 Vibrio cholerae M66-2 hypothetical protein YP_002812340.1 680532 R 579112 CDS YP_002812341.1 227812331 7780947 682485..683042 1 NC_012580.1 MutT/nudix family protein 683042 7780947 VCM66_A0723 Vibrio cholerae M66-2 MutT/nudix family protein YP_002812341.1 682485 D 579112 CDS YP_002812342.1 227812332 7780948 683027..684058 1 NC_012580.1 L-allo-threonine aldolase 684058 ybjU 7780948 ybjU Vibrio cholerae M66-2 L-allo-threonine aldolase YP_002812342.1 683027 D 579112 CDS YP_002812343.1 227812333 7780949 684055..684495 1 NC_012580.1 cytochrome c554 684495 7780949 VCM66_A0725 Vibrio cholerae M66-2 cytochrome c554 YP_002812343.1 684055 D 579112 CDS YP_002812344.1 227812334 7780950 684599..685333 1 NC_012580.1 TetR family transcriptional regulator 685333 7780950 VCM66_A0726 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002812344.1 684599 D 579112 CDS YP_002812345.1 227812335 7780951 complement(685433..686701) 1 NC_012580.1 ATP-dependent RNA helicase, DEAD box family 686701 7780951 VCM66_A0727 Vibrio cholerae M66-2 ATP-dependent RNA helicase, DEAD box family YP_002812345.1 685433 R 579112 CDS YP_002812346.1 227812336 7780952 complement(686738..687319) 1 NC_012580.1 hypothetical protein 687319 7780952 VCM66_A0728 Vibrio cholerae M66-2 hypothetical protein YP_002812346.1 686738 R 579112 CDS YP_002812347.1 227812337 7780953 complement(687356..687475) 1 NC_012580.1 hypothetical protein 687475 7780953 VCM66_A0729 Vibrio cholerae M66-2 hypothetical protein YP_002812347.1 687356 R 579112 CDS YP_002812348.1 227812338 7780954 complement(687503..687604) 1 NC_012580.1 hypothetical protein 687604 7780954 VCM66_A0730 Vibrio cholerae M66-2 hypothetical protein YP_002812348.1 687503 R 579112 CDS YP_002812349.1 227812339 7780955 687839..689041 1 NC_012580.1 tyrosine-specific transport protein 689041 tyrP 7780955 tyrP Vibrio cholerae M66-2 tyrosine-specific transport protein YP_002812349.1 687839 D 579112 CDS YP_002812350.1 227812340 7780956 689269..690690 1 NC_012580.1 methyl-accepting chemotaxis protein 690690 7780956 VCM66_A0732 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812350.1 689269 D 579112 CDS YP_002812351.1 227812341 7780957 complement(690776..691792) 1 NC_012580.1 UDP-glucose 4-epimerase 691792 galE-2 7780957 galE-2 Vibrio cholerae M66-2 UDP-glucose 4-epimerase YP_002812351.1 690776 R 579112 CDS YP_002812352.1 227812342 7780958 692112..692852 1 NC_012580.1 LamB/YcsF family protein 692852 7780958 VCM66_A0735 Vibrio cholerae M66-2 LamB/YcsF family protein YP_002812352.1 692112 D 579112 CDS YP_002812353.1 227812343 7780959 692856..693566 1 NC_012580.1 hypothetical protein 693566 7780959 VCM66_A0736 Vibrio cholerae M66-2 hypothetical protein YP_002812353.1 692856 D 579112 CDS YP_002812354.1 227812344 7780960 693676..694605 1 NC_012580.1 hypothetical protein 694605 7780960 VCM66_A0737 Vibrio cholerae M66-2 hypothetical protein YP_002812354.1 693676 D 579112 CDS YP_002812355.1 227812345 7780961 complement(694657..696090) 1 NC_012580.1 hypothetical protein 696090 7780961 VCM66_A0738 Vibrio cholerae M66-2 hypothetical protein YP_002812355.1 694657 R 579112 CDS YP_002812356.1 227812346 7780962 complement(696199..697365) 1 NC_012580.1 UDP-glucose 6-dehydrogenase 697365 ugd 7780962 ugd Vibrio cholerae M66-2 UDP-glucose 6-dehydrogenase YP_002812356.1 696199 R 579112 CDS YP_002812357.1 227812347 7780963 complement(697754..700201) 1 NC_012580.1 hypothetical protein 700201 7780963 VCM66_A0740 Vibrio cholerae M66-2 hypothetical protein YP_002812357.1 697754 R 579112 CDS YP_002812358.1 227812348 7780964 complement(700198..700875) 1 NC_012580.1 ABC transporter ATP-binding protein 700875 7780964 VCM66_A0741 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812358.1 700198 R 579112 CDS YP_002812359.1 227812349 7780965 700826..701473 1 NC_012580.1 arylesterase 701473 7780965 VCM66_A0742 Vibrio cholerae M66-2 arylesterase YP_002812359.1 700826 D 579112 CDS YP_002812360.1 227812350 7780966 701563..702771 1 NC_012580.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase 702771 7780966 VCM66_A0743 Vibrio cholerae M66-2 trans-2-enoyl-CoA reductase YP_002812360.1 701563 D 579112 CDS YP_002812361.1 227812351 7780967 702940..704823 1 NC_012580.1 GGDEF family protein 704823 7780967 VCM66_A0744 Vibrio cholerae M66-2 GGDEF family protein YP_002812361.1 702940 D 579112 CDS YP_002812362.1 227812352 7780968 704949..706598 1 NC_012580.1 hypothetical protein 706598 7780968 VCM66_A0745 Vibrio cholerae M66-2 hypothetical protein YP_002812362.1 704949 D 579112 CDS YP_002812363.1 227812353 7780969 complement(706595..706699) 1 NC_012580.1 hypothetical protein 706699 7780969 VCM66_A0746 Vibrio cholerae M66-2 hypothetical protein YP_002812363.1 706595 R 579112 CDS YP_002812364.1 227812354 7780970 complement(706756..707385) 1 NC_012580.1 DnaJ-related protein 707385 7780970 VCM66_A0747 Vibrio cholerae M66-2 DnaJ-related protein YP_002812364.1 706756 R 579112 CDS YP_002812365.1 227812355 7780971 707621..708208 1 NC_012580.1 hypothetical protein 708208 7780971 VCM66_A0748 Vibrio cholerae M66-2 hypothetical protein YP_002812365.1 707621 D 579112 CDS YP_002812366.1 227812356 7780972 708382..709761 1 NC_012580.1 hypothetical protein 709761 7780972 VCM66_A0749 Vibrio cholerae M66-2 hypothetical protein YP_002812366.1 708382 D 579112 CDS YP_002812367.1 227812357 7780973 complement(709754..710626) 1 NC_012580.1 ISVch4 transposase, OrfB 710626 orfB 7780973 orfB Vibrio cholerae M66-2 ISVch4 transposase, OrfB YP_002812367.1 709754 R 579112 CDS YP_002812368.1 227812358 7780974 complement(710623..710967) 1 NC_012580.1 ISVch4 transposase, OrfA 710967 orfA 7780974 orfA Vibrio cholerae M66-2 ISVch4 transposase, OrfA YP_002812368.1 710623 R 579112 CDS YP_002812369.1 227812359 7780975 711044..711526 1 NC_012580.1 hypothetical protein 711526 7780975 VCM66_A0752 Vibrio cholerae M66-2 hypothetical protein YP_002812369.1 711044 D 579112 CDS YP_002812370.1 227812360 7780976 711527..711820 1 NC_012580.1 hypothetical protein 711820 7780976 VCM66_A0753 Vibrio cholerae M66-2 hypothetical protein YP_002812370.1 711527 D 579112 CDS YP_002812371.1 227812361 7780977 712035..712991 1 NC_012580.1 putative resolvase 712991 7780977 VCM66_A0754 Vibrio cholerae M66-2 putative resolvase YP_002812371.1 712035 D 579112 CDS YP_002812372.1 227812362 7780978 713078..713176 1 NC_012580.1 hypothetical protein 713176 7780978 VCM66_A0755 Vibrio cholerae M66-2 hypothetical protein YP_002812372.1 713078 D 579112 CDS YP_002812373.1 227812363 7780979 713229..713450 1 NC_012580.1 hypothetical protein 713450 7780979 VCM66_A0756 Vibrio cholerae M66-2 hypothetical protein YP_002812373.1 713229 D 579112 CDS YP_002812374.1 227812364 7780980 complement(713646..714326) 1 NC_012580.1 CbbY family protein 714326 7780980 VCM66_A0757 Vibrio cholerae M66-2 CbbY family protein YP_002812374.1 713646 R 579112 CDS YP_002812375.1 227812365 7780981 complement(714465..714971) 1 NC_012580.1 hypothetical protein 714971 7780981 VCM66_A0758 Vibrio cholerae M66-2 hypothetical protein YP_002812375.1 714465 R 579112 CDS YP_002812376.1 227812366 7780982 715293..715775 1 NC_012580.1 creA protein 715775 creA 7780982 creA Vibrio cholerae M66-2 creA protein YP_002812376.1 715293 D 579112 CDS YP_002812377.1 227812367 7780983 715894..717198 1 NC_012580.1 inosine-guanosine kinase 717198 gsk-2 7780983 gsk-2 Vibrio cholerae M66-2 inosine-guanosine kinase YP_002812377.1 715894 D 579112 CDS YP_002812378.1 227812368 7780984 complement(717284..719257) 1 NC_012580.1 hypothetical protein 719257 7780984 VCM66_A0761 Vibrio cholerae M66-2 hypothetical protein YP_002812378.1 717284 R 579112 CDS YP_002812379.1 227812369 7780985 complement(719339..720331) 1 NC_012580.1 putative serine protease 720331 7780985 VCM66_A0762 Vibrio cholerae M66-2 putative serine protease YP_002812379.1 719339 R 579112 CDS YP_002812380.1 227812370 7780986 complement(720475..722466) 1 NC_012580.1 ATP-dependent RNA helicase DeaD 722466 deaD 7780986 deaD Vibrio cholerae M66-2 ATP-dependent RNA helicase DeaD YP_002812380.1 720475 R 579112 CDS YP_002812381.1 227812371 7780987 722780..724816 1 NC_012580.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 724816 rnb 7780987 rnb Vibrio cholerae M66-2 exoribonuclease II YP_002812381.1 722780 D 579112 CDS YP_002812382.1 227812372 7780988 complement(724911..725384) 1 NC_012580.1 hypothetical protein 725384 7780988 VCM66_A0765 Vibrio cholerae M66-2 hypothetical protein YP_002812382.1 724911 R 579112 CDS YP_002812383.1 227812373 7780989 725472..726308 1 NC_012580.1 ABC transporter substrate-binding protein 726308 7780989 VCM66_A0766 Vibrio cholerae M66-2 ABC transporter substrate-binding protein YP_002812383.1 725472 D 579112 CDS YP_002812384.1 227812374 7780990 complement(726454..727146) 1 NC_012580.1 NodN-related protein 727146 7780990 VCM66_A0767 Vibrio cholerae M66-2 NodN-related protein YP_002812384.1 726454 R 579112 CDS YP_002812385.1 227812375 7780991 complement(727420..728970) 1 NC_012580.1 hypothetical protein 728970 7780991 VCM66_A0768 Vibrio cholerae M66-2 hypothetical protein YP_002812385.1 727420 R 579112 CDS YP_002812386.1 227812376 7780992 complement(729296..729433) 1 NC_012580.1 hypothetical protein 729433 7780992 VCM66_A0769 Vibrio cholerae M66-2 hypothetical protein YP_002812386.1 729296 R 579112 CDS YP_002812387.1 227812377 7780993 729464..730921 1 NC_012580.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells; N-acetylglucosamine-binding protein A 730921 7780993 VCM66_A0770 Vibrio cholerae M66-2 N-acetylglucosamine-binding protein A YP_002812387.1 729464 D 579112 CDS YP_002812388.1 227812378 7780994 731249..732679 1 NC_012580.1 leucine aminopeptidase-related protein 732679 7780994 VCM66_A0771 Vibrio cholerae M66-2 leucine aminopeptidase-related protein YP_002812388.1 731249 D 579112 CDS YP_002812389.1 227812379 7780995 732714..734219 1 NC_012580.1 aminopeptidase 734219 7780995 VCM66_A0772 Vibrio cholerae M66-2 aminopeptidase YP_002812389.1 732714 D 579112 CDS YP_002812390.1 227812380 7780996 complement(734407..735336) 1 NC_012580.1 catalyzes the formation of putrescine from agmatine; agmatinase 735336 speB 7780996 speB Vibrio cholerae M66-2 agmatinase YP_002812390.1 734407 R 579112 CDS YP_002812391.1 227812381 7780997 complement(735337..737322) 1 NC_012580.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 737322 speA 7780997 speA Vibrio cholerae M66-2 arginine decarboxylase YP_002812391.1 735337 R 579112 CDS YP_002812392.1 227812382 7780998 complement(737392..737538) 1 NC_012580.1 hypothetical protein 737538 7780998 VCM66_A0775 Vibrio cholerae M66-2 hypothetical protein YP_002812392.1 737392 R 579112 CDS YP_002812393.1 227812383 7780999 737670..738254 1 NC_012580.1 hypothetical protein 738254 7780999 VCM66_A0776 Vibrio cholerae M66-2 hypothetical protein YP_002812393.1 737670 D 579112 CDS YP_002812394.1 227812384 7781000 738257..739603 1 NC_012580.1 putative magnesium transporter MgtE 739603 7781000 VCM66_A0777 Vibrio cholerae M66-2 putative magnesium transporter MgtE YP_002812394.1 738257 D 579112 CDS YP_002812395.1 227812385 7781001 739805..740095 1 NC_012580.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 740095 groES 7781001 groES Vibrio cholerae M66-2 co-chaperonin GroES YP_002812395.1 739805 D 579112 CDS YP_002812396.1 227812386 7781002 740124..741716 1 NC_012580.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; chaperonin GroEL 741716 groEL 7781002 groEL Vibrio cholerae M66-2 chaperonin GroEL YP_002812396.1 740124 D 579112 CDS YP_002812397.1 227812387 7781003 741749..741955 1 NC_012580.1 hypothetical protein 741955 7781003 VCM66_A0780 Vibrio cholerae M66-2 hypothetical protein YP_002812397.1 741749 D 579112 CDS YP_002812398.1 227812388 7781004 complement(742036..743460) 1 NC_012580.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; aspartate kinase 743460 7781004 VCM66_A0781 Vibrio cholerae M66-2 aspartate kinase YP_002812398.1 742036 R 579112 CDS YP_002812399.1 227812389 7781005 complement(743457..743873) 1 NC_012580.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid; L-ectoine synthase 743873 ectC 7781005 ectC Vibrio cholerae M66-2 L-ectoine synthase YP_002812399.1 743457 R 579112 CDS YP_002812400.1 227812390 7781006 complement(743909..745174) 1 NC_012580.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 745174 ectB 7781006 ectB Vibrio cholerae M66-2 diaminobutyrate--2-oxoglutarate aminotransferase YP_002812400.1 743909 R 579112 CDS YP_002812401.1 227812391 7781007 complement(745198..745719) 1 NC_012580.1 L-2,4-diaminobutyric acid acetyltransferase 745719 ectA 7781007 ectA Vibrio cholerae M66-2 L-2,4-diaminobutyric acid acetyltransferase YP_002812401.1 745198 R 579112 CDS YP_002812402.1 227812392 7781008 complement(745833..745949) 1 NC_012580.1 hypothetical protein 745949 7781008 VCM66_A0785 Vibrio cholerae M66-2 hypothetical protein YP_002812402.1 745833 R 579112 CDS YP_002812403.1 227812393 7781009 complement(746420..746749) 1 NC_012580.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 746749 phhB 7781009 phhB Vibrio cholerae M66-2 pterin-4-alpha-carbinolamine dehydratase YP_002812403.1 746420 R 579112 CDS YP_002812404.1 227812394 7781010 complement(746739..747608) 1 NC_012580.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin; phenylalanine 4-monooxygenase 747608 phhA 7781010 phhA Vibrio cholerae M66-2 phenylalanine 4-monooxygenase YP_002812404.1 746739 R 579112 CDS YP_002812405.1 227812395 7781011 747767..749746 1 NC_012580.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 749746 acs-2 7781011 acs-2 Vibrio cholerae M66-2 acetoacetyl-CoA synthetase YP_002812405.1 747767 D 579112 CDS YP_002812406.1 227812396 7781012 749820..750794 1 NC_012580.1 LysR family transcriptional regulator 750794 7781012 VCM66_A0789 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812406.1 749820 D 579112 CDS YP_002812407.1 227812397 7781013 750796..750990 1 NC_012580.1 hypothetical protein 750990 7781013 VCM66_A0790 Vibrio cholerae M66-2 hypothetical protein YP_002812407.1 750796 D 579112 CDS YP_002812408.1 227812398 7781014 complement(751294..751926) 1 NC_012580.1 putative methyltransferase 751926 7781014 VCM66_A0791 Vibrio cholerae M66-2 putative methyltransferase YP_002812408.1 751294 R 579112 CDS YP_002812409.1 227812399 7781015 752068..752946 1 NC_012580.1 LysR family transcriptional regulator 752946 7781015 VCM66_A0792 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812409.1 752068 D 579112 CDS YP_002812410.1 227812400 7781016 753083..754036 1 NC_012580.1 hypothetical protein 754036 7781016 VCM66_A0793 Vibrio cholerae M66-2 hypothetical protein YP_002812410.1 753083 D 579112 CDS YP_002812411.1 227812401 7781017 complement(754068..755054) 1 NC_012580.1 hypothetical protein 755054 7781017 VCM66_A0794 Vibrio cholerae M66-2 hypothetical protein YP_002812411.1 754068 R 579112 CDS YP_002812412.1 227812402 7781018 complement(755092..755670) 1 NC_012580.1 hexapeptide-repeat containing-acetyltransferase 755670 7781018 VCM66_A0795 Vibrio cholerae M66-2 hexapeptide-repeat containing-acetyltransferase YP_002812412.1 755092 R 579112 CDS YP_002812413.1 227812403 7781019 complement(755808..757121) 1 NC_012580.1 putative hemolysin 757121 7781019 VCM66_A0796 Vibrio cholerae M66-2 putative hemolysin YP_002812413.1 755808 R 579112 CDS YP_002812414.1 227812404 7781020 complement(757276..757680) 1 NC_012580.1 hypothetical protein 757680 7781020 VCM66_A0797 Vibrio cholerae M66-2 hypothetical protein YP_002812414.1 757276 R 579112 CDS YP_002812415.1 227812405 7781021 757702..757833 1 NC_012580.1 hypothetical protein 757833 7781021 VCM66_A0798 Vibrio cholerae M66-2 hypothetical protein YP_002812415.1 757702 D 579112 CDS YP_002812416.1 227812406 7781022 758573..759058 1 NC_012580.1 putative deoxycytidylate deaminase 759058 7781022 VCM66_A0799 Vibrio cholerae M66-2 putative deoxycytidylate deaminase YP_002812416.1 758573 D 579112 CDS YP_002812417.1 227812407 7781023 complement(759112..759243) 1 NC_012580.1 hypothetical protein 759243 7781023 VCM66_A0800 Vibrio cholerae M66-2 hypothetical protein YP_002812417.1 759112 R 579112 CDS YP_002812418.1 227812408 7781024 complement(759488..759640) 1 NC_012580.1 hypothetical protein 759640 7781024 VCM66_A0801 Vibrio cholerae M66-2 hypothetical protein YP_002812418.1 759488 R 579112 CDS YP_002812419.1 227812409 7781025 759714..761243 1 NC_012580.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; glyceraldehyde-3-phosphate dehydrogenase 761243 gapA-2 7781025 gapA-2 Vibrio cholerae M66-2 glyceraldehyde-3-phosphate dehydrogenase YP_002812419.1 759714 D 579112 CDS YP_002812420.1 227812410 7781026 761359..761505 1 NC_012580.1 hypothetical protein 761505 7781026 VCM66_A0803 Vibrio cholerae M66-2 hypothetical protein YP_002812420.1 761359 D 579112 CDS YP_002812421.1 227812411 7781027 761457..761768 1 NC_012580.1 hypothetical protein 761768 7781027 VCM66_A0804 Vibrio cholerae M66-2 hypothetical protein YP_002812421.1 761457 D 579112 CDS YP_002812422.1 227812412 7781028 complement(761817..762431) 1 NC_012580.1 hypothetical protein 762431 7781028 VCM66_A0805 Vibrio cholerae M66-2 hypothetical protein YP_002812422.1 761817 R 579112 CDS YP_002812423.1 227812413 7781029 762539..763861 1 NC_012580.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 763861 7781029 VCM66_A0806 Vibrio cholerae M66-2 inner membrane protein YjeH YP_002812423.1 762539 D 579112 CDS YP_002812424.1 227812414 7781030 complement(763904..764884) 1 NC_012580.1 GGDEF family protein 764884 7781030 VCM66_A0807 Vibrio cholerae M66-2 GGDEF family protein YP_002812424.1 763904 R 579112 CDS YP_002812425.1 227812415 7781031 complement(765015..774806) 1 NC_012580.1 hypothetical protein 774806 7781031 VCM66_A0808 Vibrio cholerae M66-2 hypothetical protein YP_002812425.1 765015 R 579112 CDS YP_002812426.1 227812416 7781032 complement(775107..775892) 1 NC_012580.1 response regulator 775892 7781032 VCM66_A0809 Vibrio cholerae M66-2 response regulator YP_002812426.1 775107 R 579112 CDS YP_002812427.1 227812417 7781033 complement(776052..777131) 1 NC_012580.1 hypothetical protein 777131 7781033 VCM66_A0810 Vibrio cholerae M66-2 hypothetical protein YP_002812427.1 776052 R 579112 CDS YP_002812428.1 227812418 7781034 complement(777132..778376) 1 NC_012580.1 hypothetical protein 778376 7781034 VCM66_A0811 Vibrio cholerae M66-2 hypothetical protein YP_002812428.1 777132 R 579112 CDS YP_002812429.1 227812419 7781035 complement(778381..779124) 1 NC_012580.1 hypothetical protein 779124 7781035 VCM66_A0812 Vibrio cholerae M66-2 hypothetical protein YP_002812429.1 778381 R 579112 CDS YP_002812430.1 227812420 7781036 complement(779117..780376) 1 NC_012580.1 hypothetical protein 780376 7781036 VCM66_A0813 Vibrio cholerae M66-2 hypothetical protein YP_002812430.1 779117 R 579112 CDS YP_002812431.1 227812421 7781037 complement(780364..781047) 1 NC_012580.1 ABC transporter ATP-binding protein 781047 7781037 VCM66_A0814 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812431.1 780364 R 579112 CDS YP_002812432.1 227812422 7781038 complement(781056..781727) 1 NC_012580.1 hypothetical protein 781727 7781038 VCM66_A0815 Vibrio cholerae M66-2 hypothetical protein YP_002812432.1 781056 R 579112 CDS YP_002812433.1 227812423 7781039 781754..781888 1 NC_012580.1 hypothetical protein 781888 7781039 VCM66_A0816 Vibrio cholerae M66-2 hypothetical protein YP_002812433.1 781754 D 579112 CDS YP_002812434.1 227812424 7781040 781889..782032 1 NC_012580.1 hypothetical protein 782032 7781040 VCM66_A0817 Vibrio cholerae M66-2 hypothetical protein YP_002812434.1 781889 D 579112 CDS YP_002812435.1 227812425 7781041 complement(782040..782963) 1 NC_012580.1 oxidoreductase, aldo/keto reductase 2 family 782963 7781041 VCM66_A0818 Vibrio cholerae M66-2 oxidoreductase, aldo/keto reductase 2 family YP_002812435.1 782040 R 579112 CDS YP_002812436.1 227812426 7781042 783255..785327 1 NC_012580.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase precursor 785327 malS 7781042 malS Vibrio cholerae M66-2 periplasmic alpha-amylase precursor YP_002812436.1 783255 D 579112 CDS YP_002812437.1 227812427 7781043 785269..785502 1 NC_012580.1 hypothetical protein 785502 7781043 VCM66_A0820 Vibrio cholerae M66-2 hypothetical protein YP_002812437.1 785269 D 579112 CDS YP_002812438.1 227812428 7781044 785862..787100 1 NC_012580.1 long-chain fatty acid transport protein 787100 fadL-3 7781044 fadL-3 Vibrio cholerae M66-2 long-chain fatty acid transport protein YP_002812438.1 785862 D 579112 CDS YP_002812439.1 227812429 7781045 787116..789506 1 NC_012580.1 putative lipase 789506 7781045 VCM66_A0822 Vibrio cholerae M66-2 putative lipase YP_002812439.1 787116 D 579112 CDS YP_002812440.1 227812430 7781046 789867..791264 1 NC_012580.1 methyl-accepting chemotaxis protein 791264 7781046 VCM66_A0823 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812440.1 789867 D 579112 CDS YP_002812441.1 227812431 7781047 complement(791345..793174) 1 NC_012580.1 hemagglutinin/protease 793174 hap 7781047 hap Vibrio cholerae M66-2 hemagglutinin/protease YP_002812441.1 791345 R 579112 CDS YP_002812442.1 227812432 7781048 793160..793399 1 NC_012580.1 hypothetical protein 793399 7781048 VCM66_A0825 Vibrio cholerae M66-2 hypothetical protein YP_002812442.1 793160 D 579112 CDS YP_002812443.1 227812433 7781049 complement(793595..794248) 1 NC_012580.1 receptor for colicin S4; outer membrane protein W 794248 ompW 7781049 ompW Vibrio cholerae M66-2 outer membrane protein W YP_002812443.1 793595 R 579112 CDS YP_002812444.1 227812434 7781050 794438..794671 1 NC_012580.1 hypothetical protein 794671 7781050 VCM66_A0827 Vibrio cholerae M66-2 hypothetical protein YP_002812444.1 794438 D 579112 CDS YP_002812445.1 227812435 7781051 complement(795068..795166) 1 NC_012580.1 hypothetical protein 795166 7781051 VCM66_A0828 Vibrio cholerae M66-2 hypothetical protein YP_002812445.1 795068 R 579112 CDS YP_002812446.1 227812436 7781052 795202..796152 1 NC_012580.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 796152 pbpG 7781052 pbpG Vibrio cholerae M66-2 D-alanyl-D-alanine endopeptidase YP_002812446.1 795202 D 579112 CDS YP_002812447.1 227812437 7781053 796387..797808 1 NC_012580.1 GntR family transcriptional regulator 797808 7781053 VCM66_A0830 Vibrio cholerae M66-2 GntR family transcriptional regulator YP_002812447.1 796387 D 579112 CDS YP_002812448.1 227812438 7781054 797937..799529 1 NC_012580.1 cytochrome d ubiquinol oxidase, subunit I 799529 cydA-2 7781054 cydA-2 Vibrio cholerae M66-2 cytochrome d ubiquinol oxidase, subunit I YP_002812448.1 797937 D 579112 CDS YP_002812449.1 227812439 7781055 799542..800678 1 NC_012580.1 cytochrome d ubiquinol oxidase, subunit II 800678 cydB-2 7781055 cydB-2 Vibrio cholerae M66-2 cytochrome d ubiquinol oxidase, subunit II YP_002812449.1 799542 D 579112 CDS YP_002812450.1 227812440 7781056 801500..801703 1 NC_012580.1 hypothetical protein 801703 7781056 VCM66_A0833 Vibrio cholerae M66-2 hypothetical protein YP_002812450.1 801500 D 579112 CDS YP_002812451.1 227812441 7781057 complement(801920..803245) 1 NC_012580.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 803245 dsdA 7781057 dsdA Vibrio cholerae M66-2 D-serine dehydratase YP_002812451.1 801920 R 579112 CDS YP_002812452.1 227812442 7781058 803453..804397 1 NC_012580.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 804397 dsdC 7781058 dsdC Vibrio cholerae M66-2 DNA-binding transcriptional regulator DsdC YP_002812452.1 803453 D 579112 CDS YP_002812453.1 227812443 7781059 804697..805773 1 NC_012580.1 putative hydrolase 805773 7781059 VCM66_A0836 Vibrio cholerae M66-2 putative hydrolase YP_002812453.1 804697 D 579112 CDS YP_002812454.1 227812444 7781060 805881..806042 1 NC_012580.1 integrase-related protein 806042 7781060 VCM66_A0837 Vibrio cholerae M66-2 integrase-related protein YP_002812454.1 805881 D 579112 CDS YP_002812455.1 227812445 7781061 complement(806571..806726) 1 NC_012580.1 hypothetical protein 806726 7781061 VCM66_A0838 Vibrio cholerae M66-2 hypothetical protein YP_002812455.1 806571 R 579112 CDS YP_002812456.1 227812446 7781062 806671..807051 1 NC_012580.1 hypothetical protein 807051 7781062 VCM66_A0839 Vibrio cholerae M66-2 hypothetical protein YP_002812456.1 806671 D 579112 CDS YP_002812457.1 227812447 7781063 807076..807471 1 NC_012580.1 hypothetical protein 807471 7781063 VCM66_A0840 Vibrio cholerae M66-2 hypothetical protein YP_002812457.1 807076 D 579112 CDS YP_002812458.1 227812448 7781064 807483..808547 1 NC_012580.1 hypothetical protein 808547 7781064 VCM66_A0841 Vibrio cholerae M66-2 hypothetical protein YP_002812458.1 807483 D 579112 CDS YP_002812459.1 227812449 7781065 808560..809669 1 NC_012580.1 hypothetical protein 809669 7781065 VCM66_A0842 Vibrio cholerae M66-2 hypothetical protein YP_002812459.1 808560 D 579112 CDS YP_002812460.1 227812450 7781066 809720..810781 1 NC_012580.1 hypothetical protein 810781 7781066 VCM66_A0843 Vibrio cholerae M66-2 hypothetical protein YP_002812460.1 809720 D 579112 CDS YP_002812461.1 227812451 7781067 complement(810916..811089) 1 NC_012580.1 hypothetical protein 811089 7781067 VCM66_A0844 Vibrio cholerae M66-2 hypothetical protein YP_002812461.1 810916 R 579112 CDS YP_002812462.1 227812452 7781068 complement(811878..812909) 1 NC_012580.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 812909 tdh 7781068 tdh Vibrio cholerae M66-2 L-threonine 3-dehydrogenase YP_002812462.1 811878 R 579112 CDS YP_002812463.1 227812453 7781069 complement(812912..814105) 1 NC_012580.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 814105 kbl 7781069 kbl Vibrio cholerae M66-2 2-amino-3-ketobutyrate coenzyme A ligase YP_002812463.1 812912 R 579112 CDS YP_002812464.1 227812454 7781071 815262..816023 1 NC_012580.1 transcriptional regulator, LuxR family 816023 7781071 VCM66_A0848 Vibrio cholerae M66-2 transcriptional regulator, LuxR family YP_002812464.1 815262 D 579112 CDS YP_002812465.1 227812455 7781072 816123..817061 1 NC_012580.1 LysR family transcriptional regulator 817061 7781072 VCM66_A0849 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812465.1 816123 D 579112 CDS YP_002812466.1 227812456 7781073 817055..817438 1 NC_012580.1 glyoxylase I family protein 817438 7781073 VCM66_A0850 Vibrio cholerae M66-2 glyoxylase I family protein YP_002812466.1 817055 D 579112 CDS YP_002812467.1 227812457 7781074 complement(817516..818928) 1 NC_012580.1 hypothetical protein 818928 7781074 VCM66_A0851 Vibrio cholerae M66-2 hypothetical protein YP_002812467.1 817516 R 579112 CDS YP_002812468.1 227812458 7781075 complement(819040..819438) 1 NC_012580.1 hypothetical protein 819438 7781075 VCM66_A0852 Vibrio cholerae M66-2 hypothetical protein YP_002812468.1 819040 R 579112 CDS YP_002812469.1 227812459 7781076 complement(819544..820053) 1 NC_012580.1 hypothetical protein 820053 7781076 VCM66_A0853 Vibrio cholerae M66-2 hypothetical protein YP_002812469.1 819544 R 579112 CDS YP_002812470.1 227812460 7781077 complement(820004..820750) 1 NC_012580.1 putative hydrolase 820750 7781077 VCM66_A0854 Vibrio cholerae M66-2 putative hydrolase YP_002812470.1 820004 R 579112 CDS YP_002812471.1 227812461 7781078 820918..823863 1 NC_012580.1 chemotactic transducer-related protein 823863 7781078 VCM66_A0855 Vibrio cholerae M66-2 chemotactic transducer-related protein YP_002812471.1 820918 D 579112 CDS YP_002812472.1 227812462 7781079 824207..825712 1 NC_012580.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 825712 zwf 7781079 zwf Vibrio cholerae M66-2 glucose-6-phosphate 1-dehydrogenase YP_002812472.1 824207 D 579112 CDS YP_002812473.1 227812463 7781080 825709..826425 1 NC_012580.1 devB protein 826425 devB 7781080 devB Vibrio cholerae M66-2 devB protein YP_002812473.1 825709 D 579112 CDS YP_002812474.1 227812464 7781081 826439..827887 1 NC_012580.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 827887 gnd 7781081 gnd Vibrio cholerae M66-2 6-phosphogluconate dehydrogenase YP_002812474.1 826439 D 579112 CDS YP_002812475.1 227812465 7781082 828043..828180 1 NC_012580.1 hypothetical protein 828180 7781082 VCM66_A0859 Vibrio cholerae M66-2 hypothetical protein YP_002812475.1 828043 D 579112 CDS YP_002812476.1 227812466 7781083 828448..829362 1 NC_012580.1 hypothetical protein 829362 7781083 VCM66_A0860 Vibrio cholerae M66-2 hypothetical protein YP_002812476.1 828448 D 579112 CDS YP_002812477.1 227812467 7781084 829356..829985 1 NC_012580.1 hypothetical protein 829985 7781084 VCM66_A0861 Vibrio cholerae M66-2 hypothetical protein YP_002812477.1 829356 D 579112 CDS YP_002812478.1 227812468 7781085 complement(830018..830854) 1 NC_012580.1 hypothetical protein 830854 7781085 VCM66_A0862 Vibrio cholerae M66-2 hypothetical protein YP_002812478.1 830018 R 579112 CDS YP_002812479.1 227812469 7781086 complement(830990..832123) 1 NC_012580.1 hypothetical protein 832123 7781086 VCM66_A0863 Vibrio cholerae M66-2 hypothetical protein YP_002812479.1 830990 R 579112 CDS YP_002812480.1 227812470 7781087 complement(832142..833494) 1 NC_012580.1 permease 833494 7781087 VCM66_A0864 Vibrio cholerae M66-2 permease YP_002812480.1 832142 R 579112 CDS YP_002812481.1 227812471 7781088 complement(833653..834792) 1 NC_012580.1 hypothetical protein 834792 7781088 VCM66_A0865 Vibrio cholerae M66-2 hypothetical protein YP_002812481.1 833653 R 579112 CDS YP_002812482.1 227812472 7781089 complement(834933..836669) 1 NC_012580.1 methyl-accepting chemotaxis protein 836669 7781089 VCM66_A0866 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812482.1 834933 R 579112 CDS YP_002812483.1 227812473 7781090 complement(836976..837506) 1 NC_012580.1 heme-binding protein HutZ 837506 hutZ 7781090 hutZ Vibrio cholerae M66-2 heme-binding protein HutZ YP_002812483.1 836976 R 579112 CDS YP_002812484.1 227812474 7781091 complement(837531..838112) 1 NC_012580.1 hutX protein 838112 hutX 7781091 hutX Vibrio cholerae M66-2 hutX protein YP_002812484.1 837531 R 579112 CDS YP_002812485.1 227812475 7781092 complement(838058..839425) 1 NC_012580.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 839425 hutW 7781092 hutW Vibrio cholerae M66-2 coproporphyrinogen III oxidase YP_002812485.1 838058 R 579112 CDS YP_002812486.1 227812476 7781093 839682..840431 1 NC_012580.1 tonB1 protein 840431 tonB1 7781093 tonB1 Vibrio cholerae M66-2 tonB1 protein YP_002812486.1 839682 D 579112 CDS YP_002812487.1 227812477 7781094 840431..841117 1 NC_012580.1 TonB system transport protein ExbB1 841117 exbB1 7781094 exbB1 Vibrio cholerae M66-2 TonB system transport protein ExbB1 YP_002812487.1 840431 D 579112 CDS YP_002812488.1 227812478 7781095 841114..841530 1 NC_012580.1 TonB system transport protein ExbD1 841530 exbD1 7781095 exbD1 Vibrio cholerae M66-2 TonB system transport protein ExbD1 YP_002812488.1 841114 D 579112 CDS YP_002812489.1 227812479 7781096 841541..842374 1 NC_012580.1 hemin ABC transporter, periplasmic hemin-binding protein HutB 842374 hutB 7781096 hutB Vibrio cholerae M66-2 hemin ABC transporter, periplasmic hemin-binding protein HutB YP_002812489.1 841541 D 579112 CDS YP_002812490.1 227812480 7781097 842386..843417 1 NC_012580.1 hemin ABC transporter, permease protein 843417 hutC 7781097 hutC Vibrio cholerae M66-2 hemin ABC transporter, permease protein YP_002812490.1 842386 D 579112 CDS YP_002812491.1 227812481 7781098 843486..844196 1 NC_012580.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 844196 hmuV 7781098 hmuV Vibrio cholerae M66-2 hemin importer ATP-binding subunit YP_002812491.1 843486 D 579112 CDS YP_002812492.1 227812482 7781099 complement(844271..844369) 1 NC_012580.1 hypothetical protein 844369 7781099 VCM66_A0876 Vibrio cholerae M66-2 hypothetical protein YP_002812492.1 844271 R 579112 CDS YP_002812493.1 227812483 7781100 complement(844330..844815) 1 NC_012580.1 TetR family transcriptional regulator 844815 7781100 VCM66_A0877 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002812493.1 844330 R 579112 CDS YP_002812494.1 227812484 7781101 complement(844784..844879) 1 NC_012580.1 hypothetical protein 844879 7781101 VCM66_A0878 Vibrio cholerae M66-2 hypothetical protein YP_002812494.1 844784 R 579112 CDS YP_002812495.1 227812485 7781102 845314..845616 1 NC_012580.1 hypothetical protein 845616 7781102 VCM66_A0879 Vibrio cholerae M66-2 hypothetical protein YP_002812495.1 845314 D 579112 CDS YP_002812496.1 227812486 7781103 845819..846418 1 NC_012580.1 hypothetical protein 846418 7781103 VCM66_A0880 Vibrio cholerae M66-2 hypothetical protein YP_002812496.1 845819 D 579112 CDS YP_002812497.1 227812487 7781104 complement(846479..847597) 1 NC_012580.1 putative Alkylated repair protein alkB 847597 7781104 VCM66_A0881 Vibrio cholerae M66-2 putative Alkylated repair protein alkB YP_002812497.1 846479 R 579112 CDS YP_002812498.1 227812488 7781105 847763..848371 1 NC_012580.1 hypothetical protein 848371 7781105 VCM66_A0882 Vibrio cholerae M66-2 hypothetical protein YP_002812498.1 847763 D 579112 CDS YP_002812499.1 227812489 7781106 848434..850392 1 NC_012580.1 methyl-accepting chemotaxis protein 850392 7781106 VCM66_A0883 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812499.1 848434 D 579112 CDS YP_002812500.1 227812490 7781107 complement(850455..852443) 1 NC_012580.1 hypothetical protein 852443 7781107 VCM66_A0884 Vibrio cholerae M66-2 hypothetical protein YP_002812500.1 850455 R 579112 CDS YP_002812501.1 227812491 7781108 852811..853863 1 NC_012580.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 853863 pyrC 7781108 pyrC Vibrio cholerae M66-2 dihydroorotase YP_002812501.1 852811 D 579112 CDS YP_002812502.1 227812492 7781109 complement(853927..854970) 1 NC_012580.1 AraC family transcriptional regulator 854970 7781109 VCM66_A0886 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002812502.1 853927 R 579112 CDS YP_002812503.1 227812493 7781110 855135..855485 1 NC_012580.1 hypothetical protein 855485 7781110 VCM66_A0887 Vibrio cholerae M66-2 hypothetical protein YP_002812503.1 855135 D 579112 CDS YP_002812504.1 227812494 7781111 855482..855991 1 NC_012580.1 hypothetical protein 855991 7781111 VCM66_A0888 Vibrio cholerae M66-2 hypothetical protein YP_002812504.1 855482 D 579112 CDS YP_002812505.1 227812495 7781112 complement(856058..857185) 1 NC_012580.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 857185 rumB 7781112 rumB Vibrio cholerae M66-2 23S rRNA methyluridine methyltransferase YP_002812505.1 856058 R 579112 CDS YP_002812506.1 227812496 7781113 complement(857350..858375) 1 NC_012580.1 hypothetical protein 858375 7781113 VCM66_A0890 Vibrio cholerae M66-2 hypothetical protein YP_002812506.1 857350 R 579112 CDS YP_002812507.1 227812497 7781114 complement(858398..859780) 1 NC_012580.1 hypothetical protein 859780 7781114 VCM66_A0891 Vibrio cholerae M66-2 hypothetical protein YP_002812507.1 858398 R 579112 CDS YP_002812508.1 227812498 7781115 859766..859903 1 NC_012580.1 hypothetical protein 859903 7781115 VCM66_A0892 Vibrio cholerae M66-2 hypothetical protein YP_002812508.1 859766 D 579112 CDS YP_002812509.1 227812499 7781116 860129..860341 1 NC_012580.1 cold shock domain family protein 860341 7781116 VCM66_A0893 Vibrio cholerae M66-2 cold shock domain family protein YP_002812509.1 860129 D 579112 CDS YP_002812510.1 227812500 7781117 complement(860439..860540) 1 NC_012580.1 hypothetical protein 860540 7781117 VCM66_A0894 Vibrio cholerae M66-2 hypothetical protein YP_002812510.1 860439 R 579112 CDS YP_002812511.1 227812501 7781118 860906..861262 1 NC_012580.1 hypothetical protein 861262 7781118 VCM66_A0895 Vibrio cholerae M66-2 hypothetical protein YP_002812511.1 860906 D 579112 CDS YP_002812512.1 227812502 7781119 861474..862412 1 NC_012580.1 hypothetical protein 862412 7781119 VCM66_A0896 Vibrio cholerae M66-2 hypothetical protein YP_002812512.1 861474 D 579112 CDS YP_002812513.1 227812503 7781120 complement(862401..863192) 1 NC_012580.1 AraC family transcriptional regulator 863192 7781120 VCM66_A0897 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002812513.1 862401 R 579112 CDS YP_002812514.1 227812504 7781121 863166..864191 1 NC_012580.1 hypothetical protein 864191 7781121 VCM66_A0898 Vibrio cholerae M66-2 hypothetical protein YP_002812514.1 863166 D 579112 CDS YP_002812515.1 227812505 7781122 864310..865275 1 NC_012580.1 sensory box/GGDEF family protein 865275 7781122 VCM66_A0899 Vibrio cholerae M66-2 sensory box/GGDEF family protein YP_002812515.1 864310 D 579112 CDS YP_002812516.1 227812506 7781123 865427..866188 1 NC_012580.1 transcriptional regulator, DeoR family 866188 7781123 VCM66_A0900 Vibrio cholerae M66-2 transcriptional regulator, DeoR family YP_002812516.1 865427 D 579112 CDS YP_002812517.1 227812507 7781124 866352..866840 1 NC_012580.1 acyl-CoA thioester hydrolase-related protein 866840 7781124 VCM66_A0901 Vibrio cholerae M66-2 acyl-CoA thioester hydrolase-related protein YP_002812517.1 866352 D 579112 CDS YP_002812518.1 227812508 7781125 866924..867202 1 NC_012580.1 hypothetical protein 867202 7781125 VCM66_A0902 Vibrio cholerae M66-2 hypothetical protein YP_002812518.1 866924 D 579112 CDS YP_002812519.1 227812509 7781126 complement(867525..868415) 1 NC_012580.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 868415 malG 7781126 malG Vibrio cholerae M66-2 maltose transporter permease YP_002812519.1 867525 R 579112 CDS YP_002812520.1 227812510 7781127 complement(868427..870001) 1 NC_012580.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 870001 malF 7781127 malF Vibrio cholerae M66-2 maltose transporter membrane protein YP_002812520.1 868427 R 579112 CDS YP_002812521.1 227812511 7781128 complement(870076..871263) 1 NC_012580.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 871263 malE 7781128 malE Vibrio cholerae M66-2 maltose ABC transporter periplasmic protein YP_002812521.1 870076 R 579112 CDS YP_002812522.1 227812512 7781129 871930..873051 1 NC_012580.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 873051 malK 7781129 malK Vibrio cholerae M66-2 maltose/maltodextrin transporter ATP-binding protein YP_002812522.1 871930 D 579112 CDS YP_002812523.1 227812513 7781130 873274..873795 1 NC_012580.1 spermidine n1-acetyltransferase 873795 speG 7781130 speG Vibrio cholerae M66-2 spermidine n1-acetyltransferase YP_002812523.1 873274 D 579112 CDS YP_002812524.1 227812514 7781131 873800..874045 1 NC_012580.1 hypothetical protein 874045 7781131 VCM66_A0908 Vibrio cholerae M66-2 hypothetical protein YP_002812524.1 873800 D 579112 CDS YP_002812525.1 227812515 7781132 complement(874183..874800) 1 NC_012580.1 SM-20-related protein 874800 7781132 VCM66_A0909 Vibrio cholerae M66-2 SM-20-related protein YP_002812525.1 874183 R 579112 CDS YP_002812526.1 227812516 7781133 complement(874919..875047) 1 NC_012580.1 hypothetical protein 875047 7781133 VCM66_A0910 Vibrio cholerae M66-2 hypothetical protein YP_002812526.1 874919 R 579112 CDS YP_002812527.1 227812517 7781134 875007..875327 1 NC_012580.1 hypothetical protein 875327 7781134 VCM66_A0911 Vibrio cholerae M66-2 hypothetical protein YP_002812527.1 875007 D 579112 CDS YP_002812528.1 227812518 7781135 complement(875494..876168) 1 NC_012580.1 transcriptional regulator, LuxR family 876168 7781135 VCM66_A0912 Vibrio cholerae M66-2 transcriptional regulator, LuxR family YP_002812528.1 875494 R 579112 CDS YP_002812529.1 227812519 7781136 complement(876746..877024) 1 NC_012580.1 peptidyl-prolyl cis-trans isomerase C 877024 ppiC 7781136 ppiC Vibrio cholerae M66-2 peptidyl-prolyl cis-trans isomerase C YP_002812529.1 876746 R 579112 CDS YP_002812530.1 227812520 7781137 877199..878119 1 NC_012580.1 putative chemotaxis protein CheV 878119 7781137 VCM66_A0914 Vibrio cholerae M66-2 putative chemotaxis protein CheV YP_002812530.1 877199 D 579112 CDS YP_002812531.1 227812521 7781138 complement(878195..878719) 1 NC_012580.1 transcriptional regulator, MarR family 878719 7781138 VCM66_A0915 Vibrio cholerae M66-2 transcriptional regulator, MarR family YP_002812531.1 878195 R 579112 CDS YP_002812532.1 227812522 7781139 878888..879907 1 NC_012580.1 GGDEF family protein 879907 7781139 VCM66_A0916 Vibrio cholerae M66-2 GGDEF family protein YP_002812532.1 878888 D 579112 CDS YP_002812533.1 227812523 7781140 complement(880026..880634) 1 NC_012580.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 880634 7781140 VCM66_A0917 Vibrio cholerae M66-2 malate synthase YP_002812533.1 880026 R 579112 CDS YP_002812534.1 227812524 7781141 880753..882270 1 NC_012580.1 hypothetical protein 882270 7781141 VCM66_A0918 Vibrio cholerae M66-2 hypothetical protein YP_002812534.1 880753 D 579112 CDS YP_002812535.1 227812525 7781142 complement(882373..882531) 1 NC_012580.1 hypothetical protein 882531 7781142 VCM66_A0919 Vibrio cholerae M66-2 hypothetical protein YP_002812535.1 882373 R 579112 CDS YP_002812536.1 227812526 7781143 complement(882550..883923) 1 NC_012580.1 GGDEF family protein 883923 7781143 VCM66_A0920 Vibrio cholerae M66-2 GGDEF family protein YP_002812536.1 882550 R 579112 CDS YP_002812537.1 227812527 7781144 884265..884873 1 NC_012580.1 hypothetical protein 884873 7781144 VCM66_A0921 Vibrio cholerae M66-2 hypothetical protein YP_002812537.1 884265 D 579112 CDS YP_002812538.1 227812528 7781145 885160..886368 1 NC_012580.1 hypothetical protein 886368 7781145 VCM66_A0922 Vibrio cholerae M66-2 hypothetical protein YP_002812538.1 885160 D 579112 CDS YP_002812539.1 227812529 7781146 complement(886393..887316) 1 NC_012580.1 hypothetical protein 887316 7781146 VCM66_A0923 Vibrio cholerae M66-2 hypothetical protein YP_002812539.1 886393 R 579112 CDS YP_002812540.1 227812530 7781147 887417..888322 1 NC_012580.1 putative glycine cleavage operon activator 888322 7781147 VCM66_A0924 Vibrio cholerae M66-2 putative glycine cleavage operon activator YP_002812540.1 887417 D 579112 CDS YP_002812541.1 227812531 7781148 888474..889664 1 NC_012580.1 GGDEF family protein 889664 7781148 VCM66_A0925 Vibrio cholerae M66-2 GGDEF family protein YP_002812541.1 888474 D 579112 CDS YP_002812542.1 227812532 7781149 complement(889667..889963) 1 NC_012580.1 hypothetical protein 889963 7781149 VCM66_A0926 Vibrio cholerae M66-2 hypothetical protein YP_002812542.1 889667 R 579112 CDS YP_002812543.1 227812533 7781150 complement(889926..890030) 1 NC_012580.1 hypothetical protein 890030 7781150 VCM66_A0927 Vibrio cholerae M66-2 hypothetical protein YP_002812543.1 889926 R 579112 CDS YP_002812544.1 227812534 7781151 890050..890145 1 NC_012580.1 hypothetical protein 890145 7781151 VCM66_A0928 Vibrio cholerae M66-2 hypothetical protein YP_002812544.1 890050 D 579112 CDS YP_002812545.1 227812535 7781152 890138..890986 1 NC_012580.1 pirin-related protein 890986 7781152 VCM66_A0929 Vibrio cholerae M66-2 pirin-related protein YP_002812545.1 890138 D 579112 CDS YP_002812546.1 227812536 7781153 complement(891124..891438) 1 NC_012580.1 hypothetical protein 891438 7781153 VCM66_A0930 Vibrio cholerae M66-2 hypothetical protein YP_002812546.1 891124 R 579112 CDS YP_002812547.1 227812537 7781154 891950..892390 1 NC_012580.1 hypothetical protein 892390 7781154 VCM66_A0931 Vibrio cholerae M66-2 hypothetical protein YP_002812547.1 891950 D 579112 CDS YP_002812548.1 227812538 7781155 complement(892399..893703) 1 NC_012580.1 hypothetical protein 893703 7781155 VCM66_A0932 Vibrio cholerae M66-2 hypothetical protein YP_002812548.1 892399 R 579112 CDS YP_002812549.1 227812539 7781156 893760..893933 1 NC_012580.1 hypothetical protein 893933 7781156 VCM66_A0933 Vibrio cholerae M66-2 hypothetical protein YP_002812549.1 893760 D 579112 CDS YP_002812550.1 227812540 7781157 complement(893966..895651) 1 NC_012580.1 methyl-accepting chemotaxis protein 895651 7781157 VCM66_A0934 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812550.1 893966 R 579112 CDS YP_002812551.1 227812541 7781158 complement(895866..898226) 1 NC_012580.1 ATP-dependent protease LA-related protein 898226 7781158 VCM66_A0935 Vibrio cholerae M66-2 ATP-dependent protease LA-related protein YP_002812551.1 895866 R 579112 CDS YP_002812552.1 227812542 7781159 898430..898924 1 NC_012580.1 hypothetical protein 898924 7781159 VCM66_A0936 Vibrio cholerae M66-2 hypothetical protein YP_002812552.1 898430 D 579112 CDS YP_002812553.1 227812543 7781160 898953..900572 1 NC_012580.1 ABC transporter ATP-binding protein 900572 7781160 VCM66_A0937 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812553.1 898953 D 579112 CDS YP_002812554.1 227812544 7781161 complement(900739..901470) 1 NC_012580.1 putative amino acid ABC transporter, periplasmic amino acid-binding protein 901470 7781161 VCM66_A0938 Vibrio cholerae M66-2 putative amino acid ABC transporter, periplasmic amino acid-binding protein YP_002812554.1 900739 R 579112 CDS YP_002812555.1 227812545 7781162 complement(901490..903037) 1 NC_012580.1 methyl-accepting chemotaxis protein 903037 7781162 VCM66_A0939 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812555.1 901490 R 579112 CDS YP_002812556.1 227812546 7781163 complement(903168..903911) 1 NC_012580.1 hypothetical protein 903911 7781163 VCM66_A0940 Vibrio cholerae M66-2 hypothetical protein YP_002812556.1 903168 R 579112 CDS YP_002812557.1 227812547 7781164 complement(904065..904964) 1 NC_012580.1 LysR family transcriptional regulator 904964 7781164 VCM66_A0941 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812557.1 904065 R 579112 CDS YP_002812558.1 227812548 7781165 905116..906864 1 NC_012580.1 putative L-lactate permease 906864 7781165 VCM66_A0942 Vibrio cholerae M66-2 putative L-lactate permease YP_002812558.1 905116 D 579112 CDS YP_002812559.1 227812549 7781166 906987..908123 1 NC_012580.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 908123 lldD 7781166 lldD Vibrio cholerae M66-2 L-lactate dehydrogenase YP_002812559.1 906987 D 579112 CDS YP_002812560.1 227812550 7781167 908221..911100 1 NC_012580.1 oxidoreductase/iron-sulfur cluster-binding protein 911100 7781167 VCM66_A0944 Vibrio cholerae M66-2 oxidoreductase/iron-sulfur cluster-binding protein YP_002812560.1 908221 D 579112 CDS YP_002812561.1 227812551 7781168 complement(911184..912017) 1 NC_012580.1 hypothetical protein 912017 7781168 VCM66_A0945 Vibrio cholerae M66-2 hypothetical protein YP_002812561.1 911184 R 579112 CDS YP_002812562.1 227812552 7781169 912152..914563 1 NC_012580.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 914563 ppsA 7781169 ppsA Vibrio cholerae M66-2 phosphoenolpyruvate synthase YP_002812562.1 912152 D 579112 CDS YP_002812563.1 227812553 7781170 914746..916302 1 NC_012580.1 methyl-accepting chemotaxis protein 916302 7781170 VCM66_A0947 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812563.1 914746 D 579112 CDS YP_002812564.1 227812554 7781171 916660..917994 1 NC_012580.1 hypothetical protein 917994 7781171 VCM66_A0948 Vibrio cholerae M66-2 hypothetical protein YP_002812564.1 916660 D 579112 CDS YP_002812565.1 227812555 7781172 complement(918073..919359) 1 NC_012580.1 ATP-dependent RNA helicase, DEAD box family 919359 7781172 VCM66_A0949 Vibrio cholerae M66-2 ATP-dependent RNA helicase, DEAD box family YP_002812565.1 918073 R 579112 CDS YP_002812566.1 227812556 7781173 complement(919451..920377) 1 NC_012580.1 LysR family transcriptional regulator 920377 7781173 VCM66_A0950 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812566.1 919451 R 579112 CDS YP_002812567.1 227812557 7781174 920498..921154 1 NC_012580.1 cofactor involved in the reduction of disulfides; glutaredoxin 2 921154 grx2 7781174 grx2 Vibrio cholerae M66-2 glutaredoxin 2 YP_002812567.1 920498 D 579112 CDS YP_002812568.1 227812558 7781175 921164..922267 1 NC_012580.1 N-ethylmaleimide reductase 922267 nemA 7781175 nemA Vibrio cholerae M66-2 N-ethylmaleimide reductase YP_002812568.1 921164 D 579112 CDS YP_002812569.1 227812559 7781176 complement(922388..923368) 1 NC_012580.1 hypothetical protein 923368 7781176 VCM66_A0953 Vibrio cholerae M66-2 hypothetical protein YP_002812569.1 922388 R 579112 CDS YP_002812570.1 227812560 7781177 923501..923602 1 NC_012580.1 hypothetical protein 923602 7781177 VCM66_A0954 Vibrio cholerae M66-2 hypothetical protein YP_002812570.1 923501 D 579112 CDS YP_002812571.1 227812561 7781178 923725..925584 1 NC_012580.1 ABC transporter ATP-binding protein 925584 7781178 VCM66_A0955 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812571.1 923725 D 579112 CDS YP_002812572.1 227812562 7781179 925715..926440 1 NC_012580.1 hypothetical protein 926440 7781179 VCM66_A0956 Vibrio cholerae M66-2 hypothetical protein YP_002812572.1 925715 D 579112 CDS YP_002812573.1 227812563 7781180 complement(926530..927573) 1 NC_012580.1 NADH-dependent flavin oxidoreductase, Oye family 927573 7781180 VCM66_A0957 Vibrio cholerae M66-2 NADH-dependent flavin oxidoreductase, Oye family YP_002812573.1 926530 R 579112 CDS YP_002812574.1 227812564 7781181 927723..928298 1 NC_012580.1 TetR family transcriptional regulator 928298 7781181 VCM66_A0958 Vibrio cholerae M66-2 TetR family transcriptional regulator YP_002812574.1 927723 D 579112 CDS YP_002812575.1 227812565 7781182 complement(928370..928999) 1 NC_012580.1 hypothetical protein 928999 7781182 VCM66_A0959 Vibrio cholerae M66-2 hypothetical protein YP_002812575.1 928370 R 579112 CDS YP_002812576.1 227812566 7781183 929200..930033 1 NC_012580.1 AraC family transcriptional regulator 930033 7781183 VCM66_A0960 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002812576.1 929200 D 579112 CDS YP_002812577.1 227812567 7781184 930185..930904 1 NC_012580.1 AzlC family protein 930904 7781184 VCM66_A0961 Vibrio cholerae M66-2 AzlC family protein YP_002812577.1 930185 D 579112 CDS YP_002812578.1 227812568 7781185 930901..931218 1 NC_012580.1 hypothetical protein 931218 7781185 VCM66_A0962 Vibrio cholerae M66-2 hypothetical protein YP_002812578.1 930901 D 579112 CDS YP_002812579.1 227812569 7781186 complement(931270..931884) 1 NC_012580.1 hypothetical protein 931884 7781186 VCM66_A0963 Vibrio cholerae M66-2 hypothetical protein YP_002812579.1 931270 R 579112 CDS YP_002812580.1 227812570 7781187 complement(932000..932458) 1 NC_012580.1 transcriptional regulator, MarR family 932458 7781187 VCM66_A0964 Vibrio cholerae M66-2 transcriptional regulator, MarR family YP_002812580.1 932000 R 579112 CDS YP_002812581.1 227812571 7781188 932555..932992 1 NC_012580.1 putative organic hydroperoxide resistance protein 932992 7781188 VCM66_A0965 Vibrio cholerae M66-2 putative organic hydroperoxide resistance protein YP_002812581.1 932555 D 579112 CDS YP_002812582.1 227812572 7781189 complement(933006..933104) 1 NC_012580.1 hypothetical protein 933104 7781189 VCM66_A0966 Vibrio cholerae M66-2 hypothetical protein YP_002812582.1 933006 R 579112 CDS YP_002812583.1 227812573 7781190 933248..934243 1 NC_012580.1 putative outer membrane protein 934243 7781190 VCM66_A0967 Vibrio cholerae M66-2 putative outer membrane protein YP_002812583.1 933248 D 579112 CDS YP_002812584.1 227812574 7781191 934269..934388 1 NC_012580.1 hypothetical protein 934388 7781191 VCM66_A0968 Vibrio cholerae M66-2 hypothetical protein YP_002812584.1 934269 D 579112 CDS YP_002812585.1 227812575 7781192 934404..935300 1 NC_012580.1 hypothetical protein 935300 7781192 VCM66_A0969 Vibrio cholerae M66-2 hypothetical protein YP_002812585.1 934404 D 579112 CDS YP_002812586.1 227812576 7781193 935327..935965 1 NC_012580.1 glutaredoxin-related protein 935965 7781193 VCM66_A0970 Vibrio cholerae M66-2 glutaredoxin-related protein YP_002812586.1 935327 D 579112 CDS YP_002812587.1 227812577 7781194 complement(936179..936646) 1 NC_012580.1 hypothetical protein 936646 7781194 VCM66_A0971 Vibrio cholerae M66-2 hypothetical protein YP_002812587.1 936179 R 579112 CDS YP_002812588.1 227812578 7781195 complement(936643..937374) 1 NC_012580.1 hypothetical protein 937374 7781195 VCM66_A0972 Vibrio cholerae M66-2 hypothetical protein YP_002812588.1 936643 R 579112 CDS YP_002812589.1 227812579 7781196 complement(937537..937638) 1 NC_012580.1 hypothetical protein 937638 7781196 VCM66_A0973 Vibrio cholerae M66-2 hypothetical protein YP_002812589.1 937537 R 579112 CDS YP_002812590.1 227812580 7781197 937766..939199 1 NC_012580.1 Na+/H+ antiporter 939199 nhaD 7781197 nhaD Vibrio cholerae M66-2 Na+/H+ antiporter YP_002812590.1 937766 D 579112 CDS YP_002812591.1 227812581 7781198 complement(939265..939666) 1 NC_012580.1 hypothetical protein 939666 7781198 VCM66_A0975 Vibrio cholerae M66-2 hypothetical protein YP_002812591.1 939265 R 579112 CDS YP_002812592.1 227812582 7781199 complement(939677..940150) 1 NC_012580.1 methylated-DNA--protein-cysteine S-methyltransferase 940150 ogt 7781199 ogt Vibrio cholerae M66-2 methylated-DNA--protein-cysteine S-methyltransferase YP_002812592.1 939677 R 579112 CDS YP_002812593.1 227812583 7781200 complement(940151..941509) 1 NC_012580.1 ada regulatory protein 941509 ada 7781200 ada Vibrio cholerae M66-2 ada regulatory protein YP_002812593.1 940151 R 579112 CDS YP_002812594.1 227812584 7781201 941765..942211 1 NC_012580.1 hypothetical protein 942211 7781201 VCM66_A0978 Vibrio cholerae M66-2 hypothetical protein YP_002812594.1 941765 D 579112 CDS YP_002812595.1 227812585 7781202 complement(942288..943208) 1 NC_012580.1 LysR family transcriptional regulator 943208 7781202 VCM66_A0979 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812595.1 942288 R 579112 CDS YP_002812596.1 227812586 7781203 943323..943682 1 NC_012580.1 hypothetical protein 943682 7781203 VCM66_A0980 Vibrio cholerae M66-2 hypothetical protein YP_002812596.1 943323 D 579112 CDS YP_002812597.1 227812587 7781204 943728..945752 1 NC_012580.1 hypothetical protein 945752 7781204 VCM66_A0981 Vibrio cholerae M66-2 hypothetical protein YP_002812597.1 943728 D 579112 CDS YP_002812598.1 227812588 7781205 complement(945879..946220) 1 NC_012580.1 hypothetical protein 946220 7781205 VCM66_A0982 Vibrio cholerae M66-2 hypothetical protein YP_002812598.1 945879 R 579112 CDS YP_002812599.1 227812589 7781206 946495..947295 1 NC_012580.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 947295 nagB 7781206 nagB Vibrio cholerae M66-2 glucosamine-6-phosphate deaminase YP_002812599.1 946495 D 579112 CDS YP_002812600.1 227812590 7781207 complement(947426..948583) 1 NC_012580.1 hypothetical protein 948583 7781207 VCM66_A0984 Vibrio cholerae M66-2 hypothetical protein YP_002812600.1 947426 R 579112 CDS YP_002812601.1 227812591 7781208 complement(948736..949572) 1 NC_012580.1 putative maltose operon periplasmic protein 949572 7781208 VCM66_A0985 Vibrio cholerae M66-2 putative maltose operon periplasmic protein YP_002812601.1 948736 R 579112 CDS YP_002812602.1 227812592 7781209 complement(949777..951027) 1 NC_012580.1 porin involved in the transport of maltose and maltodextrins; maltoporin 951027 lamB 7781209 lamB Vibrio cholerae M66-2 maltoporin YP_002812602.1 949777 R 579112 CDS YP_002812603.1 227812593 7781210 951447..953417 1 NC_012580.1 glycogen operon protein GlgX 953417 glgX 7781210 glgX Vibrio cholerae M66-2 glycogen operon protein GlgX YP_002812603.1 951447 D 579112 CDS YP_002812604.1 227812594 7781211 953552..953803 1 NC_012580.1 hypothetical protein 953803 7781211 VCM66_A0988 Vibrio cholerae M66-2 hypothetical protein YP_002812604.1 953552 D 579112 CDS YP_002812605.1 227812595 7781212 954263..955894 1 NC_012580.1 methyl-accepting chemotaxis protein 955894 7781212 VCM66_A0989 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812605.1 954263 D 579112 CDS YP_002812606.1 227812596 7781213 complement(956009..956416) 1 NC_012580.1 hypothetical protein 956416 7781213 VCM66_A0990 Vibrio cholerae M66-2 hypothetical protein YP_002812606.1 956009 R 579112 CDS YP_002812607.1 227812597 7781214 complement(956684..958060) 1 NC_012580.1 putative extracellular solute-binding protein 958060 7781214 VCM66_A0991 Vibrio cholerae M66-2 putative extracellular solute-binding protein YP_002812607.1 956684 R 579112 CDS YP_002812608.1 227812598 7781215 complement(958069..960069) 1 NC_012580.1 methyl-accepting chemotaxis protein 960069 7781215 VCM66_A0992 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812608.1 958069 R 579112 CDS YP_002812609.1 227812599 7781216 960183..960500 1 NC_012580.1 hypothetical protein 960500 7781216 VCM66_A0993 Vibrio cholerae M66-2 hypothetical protein YP_002812609.1 960183 D 579112 CDS YP_002812610.1 227812600 7781217 complement(960594..961760) 1 NC_012580.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 961760 7781217 VCM66_A0994 Vibrio cholerae M66-2 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002812610.1 960594 R 579112 CDS YP_002812611.1 227812601 7781218 961948..962667 1 NC_012580.1 amino acid ABC transporter ATP-binding protein 962667 7781218 VCM66_A0995 Vibrio cholerae M66-2 amino acid ABC transporter ATP-binding protein YP_002812611.1 961948 D 579112 CDS YP_002812612.1 227812602 7781219 962664..963464 1 NC_012580.1 amino acid ABC transporter permease 963464 7781219 VCM66_A0996 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002812612.1 962664 D 579112 CDS YP_002812613.1 227812603 7781220 963500..964336 1 NC_012580.1 amino acid ABC transporter substrate-binding protein 964336 7781220 VCM66_A0997 Vibrio cholerae M66-2 amino acid ABC transporter substrate-binding protein YP_002812613.1 963500 D 579112 CDS YP_002812614.1 227812604 7781221 964337..965233 1 NC_012580.1 amino acid ABC transporter permease 965233 7781221 VCM66_A0998 Vibrio cholerae M66-2 amino acid ABC transporter permease YP_002812614.1 964337 D 579112 CDS YP_002812615.1 227812605 7781222 965346..967049 1 NC_012580.1 putative phosphomannomutase 967049 7781222 VCM66_A0999 Vibrio cholerae M66-2 putative phosphomannomutase YP_002812615.1 965346 D 579112 CDS YP_002812616.1 227812606 7781223 complement(967108..967509) 1 NC_012580.1 Ccm2-related protein 967509 7781223 VCM66_A1000 Vibrio cholerae M66-2 Ccm2-related protein YP_002812616.1 967108 R 579112 CDS YP_002812617.1 227812607 7781224 complement(967419..968360) 1 NC_012580.1 tagE protein 968360 tagE-2 7781224 tagE-2 Vibrio cholerae M66-2 tagE protein YP_002812617.1 967419 R 579112 CDS YP_002812618.1 227812608 7781225 968661..968804 1 NC_012580.1 hypothetical protein 968804 7781225 VCM66_A1002 Vibrio cholerae M66-2 hypothetical protein YP_002812618.1 968661 D 579112 CDS YP_002812619.1 227812609 7781226 968943..970892 1 NC_012580.1 PTS system, mannitol-specific IIABC component 970892 mtlA 7781226 mtlA Vibrio cholerae M66-2 PTS system, mannitol-specific IIABC component YP_002812619.1 968943 D 579112 CDS YP_002812620.1 227812610 7781227 970993..972147 1 NC_012580.1 mannitol-1-phosphate 5-dehydrogenase 972147 mtlD 7781227 mtlD Vibrio cholerae M66-2 mannitol-1-phosphate 5-dehydrogenase YP_002812620.1 970993 D 579112 CDS YP_002812621.1 227812611 7781228 972196..972777 1 NC_012580.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 972777 mtlR 7781228 mtlR Vibrio cholerae M66-2 mannitol repressor protein YP_002812621.1 972196 D 579112 CDS YP_002812622.1 227812612 7781229 972891..973826 1 NC_012580.1 oxidoreductase, Gfo/Idh/MocA family 973826 7781229 VCM66_A1006 Vibrio cholerae M66-2 oxidoreductase, Gfo/Idh/MocA family YP_002812622.1 972891 D 579112 CDS YP_002812623.1 227812613 7781230 complement(973927..974805) 1 NC_012580.1 hypothetical protein 974805 7781230 VCM66_A1007 Vibrio cholerae M66-2 hypothetical protein YP_002812623.1 973927 R 579112 CDS YP_002812624.1 227812614 7781231 974939..975862 1 NC_012580.1 hypothetical protein 975862 7781231 VCM66_A1008 Vibrio cholerae M66-2 hypothetical protein YP_002812624.1 974939 D 579112 CDS YP_002812625.1 227812615 7781232 complement(975859..976290) 1 NC_012580.1 hypothetical protein 976290 7781232 VCM66_A1009 Vibrio cholerae M66-2 hypothetical protein YP_002812625.1 975859 R 579112 CDS YP_002812626.1 227812616 7781233 complement(976366..977088) 1 NC_012580.1 hypothetical protein 977088 7781233 VCM66_A1010 Vibrio cholerae M66-2 hypothetical protein YP_002812626.1 976366 R 579112 CDS YP_002812627.1 227812617 7781234 complement(977270..977770) 1 NC_012580.1 hypothetical protein 977770 7781234 VCM66_A1011 Vibrio cholerae M66-2 hypothetical protein YP_002812627.1 977270 R 579112 CDS YP_002812628.1 227812618 7781235 complement(977792..978430) 1 NC_012580.1 hypothetical protein 978430 7781235 VCM66_A1012 Vibrio cholerae M66-2 hypothetical protein YP_002812628.1 977792 R 579112 CDS YP_002812629.1 227812619 7781236 978530..979453 1 NC_012580.1 LysR family transcriptional regulator 979453 7781236 VCM66_A1013 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812629.1 978530 D 579112 CDS YP_002812630.1 227812620 7781237 complement(979496..981808) 1 NC_012580.1 methyl-accepting chemotaxis protein 981808 7781237 VCM66_A1014 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812630.1 979496 R 579112 CDS YP_002812631.1 227812621 7781238 complement(982198..982917) 1 NC_012580.1 oxidoreductase, short-chain dehydrogenase/reductase family 982917 7781238 VCM66_A1015 Vibrio cholerae M66-2 oxidoreductase, short-chain dehydrogenase/reductase family YP_002812631.1 982198 R 579112 CDS YP_002812632.1 227812622 7781239 983065..983970 1 NC_012580.1 LysR family transcriptional regulator 983970 7781239 VCM66_A1016 Vibrio cholerae M66-2 LysR family transcriptional regulator YP_002812632.1 983065 D 579112 CDS YP_002812633.1 227812623 7781240 984064..984681 1 NC_012580.1 hypothetical protein 984681 7781240 VCM66_A1017 Vibrio cholerae M66-2 hypothetical protein YP_002812633.1 984064 D 579112 CDS YP_002812634.1 227812624 7781241 complement(984746..985402) 1 NC_012580.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 985402 ribB 7781241 ribB Vibrio cholerae M66-2 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002812634.1 984746 R 579112 CDS YP_002812635.1 227812625 7781242 985709..985843 1 NC_012580.1 sensor histidine kinase 985843 7781242 VCM66_A1019 Vibrio cholerae M66-2 sensor histidine kinase YP_002812635.1 985709 D 579112 CDS YP_002812636.1 227812626 7781243 complement(985861..987180) 1 NC_012580.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 987180 potE 7781243 potE Vibrio cholerae M66-2 putrescine transporter YP_002812636.1 985861 R 579112 CDS YP_002812637.1 227812627 7781244 complement(987248..989410) 1 NC_012580.1 ornithine decarboxylase 989410 speF 7781244 speF Vibrio cholerae M66-2 ornithine decarboxylase YP_002812637.1 987248 R 579112 CDS YP_002812638.1 227812628 7781245 989551..989673 1 NC_012580.1 hypothetical protein 989673 7781245 VCM66_A1022 Vibrio cholerae M66-2 hypothetical protein YP_002812638.1 989551 D 579112 CDS YP_002812639.1 227812629 7781246 complement(989750..989872) 1 NC_012580.1 hypothetical protein 989872 7781246 VCM66_A1023 Vibrio cholerae M66-2 hypothetical protein YP_002812639.1 989750 R 579112 CDS YP_002812640.1 227812630 7781247 complement(990164..990403) 1 NC_012580.1 hypothetical protein 990403 7781247 VCM66_A1024 Vibrio cholerae M66-2 hypothetical protein YP_002812640.1 990164 R 579112 CDS YP_002812641.1 227812631 7781248 complement(990393..991835) 1 NC_012580.1 aldehyde dehydrogenase 991835 7781248 VCM66_A1025 Vibrio cholerae M66-2 aldehyde dehydrogenase YP_002812641.1 990393 R 579112 CDS YP_002812642.1 227812632 7781249 complement(992008..992490) 1 NC_012580.1 transcriptional regulator, AsnC family 992490 7781249 VCM66_A1026 Vibrio cholerae M66-2 transcriptional regulator, AsnC family YP_002812642.1 992008 R 579112 CDS YP_002812643.1 227812633 7781250 complement(992688..994607) 1 NC_012580.1 methyl-accepting chemotaxis protein 994607 7781250 VCM66_A1027 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812643.1 992688 R 579112 CDS YP_002812644.1 227812634 7781251 complement(994937..995158) 1 NC_012580.1 hypothetical protein 995158 7781251 VCM66_A1028 Vibrio cholerae M66-2 hypothetical protein YP_002812644.1 994937 R 579112 CDS YP_002812645.1 227812635 7781252 complement(995342..996832) 1 NC_012580.1 sodium/proline symporter 996832 putP 7781252 putP Vibrio cholerae M66-2 sodium/proline symporter YP_002812645.1 995342 R 579112 CDS YP_002812646.1 227812636 7781253 complement(996905..997603) 1 NC_012580.1 hypothetical protein 997603 7781253 VCM66_A1030 Vibrio cholerae M66-2 hypothetical protein YP_002812646.1 996905 R 579112 CDS YP_002812647.1 227812637 7781254 complement(997625..1000744) 1 NC_012580.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1000744 putA 7781254 putA Vibrio cholerae M66-2 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002812647.1 997625 R 579112 CDS YP_002812648.1 227812638 7781255 complement(1001084..1001947) 1 NC_012580.1 AraC family transcriptional regulator 1001947 7781255 VCM66_A1032 Vibrio cholerae M66-2 AraC family transcriptional regulator YP_002812648.1 1001084 R 579112 CDS YP_002812649.1 227812639 7781256 1002306..1003445 1 NC_012580.1 hypothetical protein 1003445 7781256 VCM66_A1033 Vibrio cholerae M66-2 hypothetical protein YP_002812649.1 1002306 D 579112 CDS YP_002812650.1 227812640 7781257 1003412..1003537 1 NC_012580.1 hypothetical protein 1003537 7781257 VCM66_A1034 Vibrio cholerae M66-2 hypothetical protein YP_002812650.1 1003412 D 579112 CDS YP_002812651.1 227812641 7781258 1003605..1005422 1 NC_012580.1 hypothetical protein 1005422 7781258 VCM66_A1035 Vibrio cholerae M66-2 hypothetical protein YP_002812651.1 1003605 D 579112 CDS YP_002812652.1 227812642 7781259 1005522..1006481 1 NC_012580.1 transcriptional regulator, LuxR family 1006481 7781259 VCM66_A1036 Vibrio cholerae M66-2 transcriptional regulator, LuxR family YP_002812652.1 1005522 D 579112 CDS YP_002812653.1 227812643 7781260 complement(1006510..1007145) 1 NC_012580.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1007145 pdxH 7781260 pdxH Vibrio cholerae M66-2 pyridoxamine 5'-phosphate oxidase YP_002812653.1 1006510 R 579112 CDS YP_002812654.1 227812644 7781261 1007315..1008760 1 NC_012580.1 secretion protein, HlyD family 1008760 7781261 VCM66_A1038 Vibrio cholerae M66-2 secretion protein, HlyD family YP_002812654.1 1007315 D 579112 CDS YP_002812655.1 227812645 7781262 1008769..1009431 1 NC_012580.1 hypothetical protein 1009431 7781262 VCM66_A1039 Vibrio cholerae M66-2 hypothetical protein YP_002812655.1 1008769 D 579112 CDS YP_002812656.1 227812646 7781263 1009437..1011347 1 NC_012580.1 putative Signaling protein ykoW 1011347 7781263 VCM66_A1040 Vibrio cholerae M66-2 putative Signaling protein ykoW YP_002812656.1 1009437 D 579112 CDS YP_002812657.1 227812647 7781264 1011362..1013476 1 NC_012580.1 toxin secretion ATP-binding protein 1013476 7781264 VCM66_A1041 Vibrio cholerae M66-2 toxin secretion ATP-binding protein YP_002812657.1 1011362 D 579112 CDS YP_002812658.1 227812648 7781265 complement(1013611..1015281) 1 NC_012580.1 hypothetical protein 1015281 7781265 VCM66_A1042 Vibrio cholerae M66-2 hypothetical protein YP_002812658.1 1013611 R 579112 CDS YP_002812659.1 227812649 7781266 complement(1015540..1017246) 1 NC_012580.1 response regulator 1017246 7781266 VCM66_A1043 Vibrio cholerae M66-2 response regulator YP_002812659.1 1015540 R 579112 CDS YP_002812660.1 227812650 7781267 complement(1017270..1017569) 1 NC_012580.1 putative anti-sigma F factor antagonist 1017569 7781267 VCM66_A1044 Vibrio cholerae M66-2 putative anti-sigma F factor antagonist YP_002812660.1 1017270 R 579112 CDS YP_002812661.1 227812651 7781268 complement(1017579..1018733) 1 NC_012580.1 methyl-accepting chemotaxis protein 1018733 7781268 VCM66_A1045 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812661.1 1017579 R 579112 CDS YP_002812662.1 227812652 7781269 complement(1018776..1019816) 1 NC_012580.1 protein-glutamate methylesterase CheB 1019816 cheB-3 7781269 cheB-3 Vibrio cholerae M66-2 protein-glutamate methylesterase CheB YP_002812662.1 1018776 R 579112 CDS YP_002812663.1 227812653 7781270 complement(1019813..1020514) 1 NC_012580.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD 1020514 7781270 VCM66_A1047 Vibrio cholerae M66-2 chemoreceptor glutamine deamidase CheD YP_002812663.1 1019813 R 579112 CDS YP_002812664.1 227812654 7781271 complement(1020453..1021283) 1 NC_012580.1 chemotaxis protein methyltransferase CheR 1021283 cheR-3 7781271 cheR-3 Vibrio cholerae M66-2 chemotaxis protein methyltransferase CheR YP_002812664.1 1020453 R 579112 CDS YP_002812665.1 227812655 7781272 complement(1021298..1023334) 1 NC_012580.1 methyl-accepting chemotaxis protein 1023334 7781272 VCM66_A1049 Vibrio cholerae M66-2 methyl-accepting chemotaxis protein YP_002812665.1 1021298 R 579112 CDS YP_002812666.1 227812656 7781273 complement(1023348..1023809) 1 NC_012580.1 purine-binding chemotaxis protein CheW 1023809 cheW-2 7781273 cheW-2 Vibrio cholerae M66-2 purine-binding chemotaxis protein CheW YP_002812666.1 1023348 R 579112 CDS YP_002812667.1 227812657 7781274 complement(1023806..1024333) 1 NC_012580.1 purine-binding chemotaxis protein CheW 1024333 cheW-3 7781274 cheW-3 Vibrio cholerae M66-2 purine-binding chemotaxis protein CheW YP_002812667.1 1023806 R 579112 CDS YP_002812668.1 227812658 7781275 complement(1024342..1026504) 1 NC_012580.1 chemotaxis protein CheA 1026504 cheA-3 7781275 cheA-3 Vibrio cholerae M66-2 chemotaxis protein CheA YP_002812668.1 1024342 R 579112 CDS YP_002812669.1 227812659 7781276 complement(1026553..1026930) 1 NC_012580.1 chemotaxis protein CheY 1026930 cheY-4 7781276 cheY-4 Vibrio cholerae M66-2 chemotaxis protein CheY YP_002812669.1 1026553 R 579112 CDS YP_002812670.1 227812660 7781277 complement(1026923..1027228) 1 NC_012580.1 hypothetical protein 1027228 7781277 VCM66_A1054 Vibrio cholerae M66-2 hypothetical protein YP_002812670.1 1026923 R 579112 CDS YP_002812671.1 227812661 7781278 1027426..1028991 1 NC_012580.1 ABC transporter substrate-binding protein 1028991 7781278 VCM66_A1055 Vibrio cholerae M66-2 ABC transporter substrate-binding protein YP_002812671.1 1027426 D 579112 CDS YP_002812672.1 227812662 7781279 1028984..1029940 1 NC_012580.1 ABC transporter permease 1029940 7781279 VCM66_A1056 Vibrio cholerae M66-2 ABC transporter permease YP_002812672.1 1028984 D 579112 CDS YP_002812673.1 227812663 7781280 1029921..1030733 1 NC_012580.1 ABC transporter permease 1030733 7781280 VCM66_A1057 Vibrio cholerae M66-2 ABC transporter permease YP_002812673.1 1029921 D 579112 CDS YP_002812674.1 227812664 7781281 1030652..1032112 1 NC_012580.1 ABC transporter ATP-binding protein 1032112 7781281 VCM66_A1058 Vibrio cholerae M66-2 ABC transporter ATP-binding protein YP_002812674.1 1030652 D 579112 CDS YP_002812675.1 227812665 7781282 1032367..1034019 1 NC_012580.1 hypothetical protein 1034019 7781282 VCM66_A1059 Vibrio cholerae M66-2 hypothetical protein YP_002812675.1 1032367 D 579112 CDS YP_002812676.1 227812666 7781283 1034060..1034158 1 NC_012580.1 hypothetical protein 1034158 7781283 VCM66_A1060 Vibrio cholerae M66-2 hypothetical protein YP_002812676.1 1034060 D 579112 CDS YP_002812677.1 227812667 7781284 complement(1034171..1035586) 1 NC_012580.1 sensor histidine kinase 1035586 7781284 VCM66_A1061 Vibrio cholerae M66-2 sensor histidine kinase YP_002812677.1 1034171 R 579112 CDS YP_002812678.1 227812668 7781285 complement(1035576..1036232) 1 NC_012580.1 DNA-binding response regulator 1036232 7781285 VCM66_A1062 Vibrio cholerae M66-2 DNA-binding response regulator YP_002812678.1 1035576 R 579112 CDS YP_002812679.1 227812669 7781286 complement(1036237..1036869) 1 NC_012580.1 hypothetical protein 1036869 7781286 VCM66_A1063 Vibrio cholerae M66-2 hypothetical protein YP_002812679.1 1036237 R 579112 CDS YP_002812680.1 227812670 7781287 complement(1036897..1037694) 1 NC_012580.1 short chain dehydrogenase 1037694 7781287 VCM66_A1064 Vibrio cholerae M66-2 short chain dehydrogenase YP_002812680.1 1036897 R 579112 CDS YP_002812681.1 227812671 7781288 complement(1037704..1038414) 1 NC_012580.1 hypothetical protein 1038414 7781288 VCM66_A1065 Vibrio cholerae M66-2 hypothetical protein YP_002812681.1 1037704 R 579112 CDS YP_002812682.1 227812672 7781289 complement(1038430..1039953) 1 NC_012580.1 putative long-chain-fatty-acid--CoA ligase 1039953 7781289 VCM66_A1066 Vibrio cholerae M66-2 putative long-chain-fatty-acid--CoA ligase YP_002812682.1 1038430 R 579112 CDS YP_002812683.1 227812673 7781290 complement(1039964..1040566) 1 NC_012580.1 thermostable hemolysin 1040566 7781290 VCM66_A1067 Vibrio cholerae M66-2 thermostable hemolysin YP_002812683.1 1039964 R 579112 CDS YP_002812684.1 227812674 7781291 complement(1040740..1042866) 1 NC_012580.1 hypothetical protein 1042866 7781291 VCM66_A1068 Vibrio cholerae M66-2 hypothetical protein YP_002812684.1 1040740 R 579112 CDS YP_002812685.1 227812675 7781292 1042994..1044025 1 NC_012580.1 spermidine/putrescine ABC transporter substrate-binding protein 1044025 7781292 VCM66_A1069 Vibrio cholerae M66-2 spermidine/putrescine ABC transporter substrate-binding protein YP_002812685.1 1042994 D 579112 CDS YP_002812686.1 227812676 7781293 complement(1044085..1045056) 1 NC_012580.1 ParB family protein 1045056 7781293 VCM66_A1070 Vibrio cholerae M66-2 ParB family protein YP_002812686.1 1044085 R 579112 CDS YP_002812687.1 227812677 7781294 complement(1045064..1046287) 1 NC_012580.1 ParA family protein 1046287 7781294 VCM66_A1071 Vibrio cholerae M66-2 ParA family protein YP_002812687.1 1045064 R 579112 CDS